BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q0WP12 (227 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3LCC-A nrPDB 468 e-132 6MRO-A nrPDB 50 6e-07 4NEC-A nrPDB 47 6e-06 3MGG-A nrPDB 44 5e-05 2H11-A nrPDB 43 1e-04 3OFK-A nrPDB 41 5e-04 1PJZ-A nrPDB 37 0.005 4FGZ-A nrPDB 35 0.019 5WP5-A nrPDB 35 0.021 3BGI-A nrPDB 35 0.039 5GM1-A nrPDB 33 0.12 3SM3-A nrPDB 32 0.19 3L8D-A nrPDB 32 0.20 3M70-A nrPDB 32 0.27 2P35-A nrPDB 31 0.38 4QDJ-A nrPDB 30 0.57 5JE5-A nrPDB 30 0.71 4KRI-A nrPDB 30 0.95 4INE-A nrPDB 30 1.00 4RVS-A nrPDB 29 1.5 2EEC-A nrPDB 28 2.9 3CCF-A nrPDB 28 4.7 6ED3-A nrPDB 27 5.1 3OU6-A nrPDB 27 6.5 3SNO-A nrPDB 27 7.6 >3LCC-A nrPDB Length = 235 Score = 468 bits (1203), Expect = e-132, Method: Compositional matrix adjust. Identities = 227/227 (100%), Positives = 227/227 (100%) Query: 1 MAEEQQNSDQSNGGNVIPTPEEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLV 60 MAEEQQNSDQSNGGNVIPTPEEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLV Sbjct: 1 MAEEQQNSDQSNGGNVIPTPEEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLV 60 Query: 61 DTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFV 120 DTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFV Sbjct: 61 DTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFV 120 Query: 121 KEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGG 180 KEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGG Sbjct: 121 KEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGG 180 Query: 181 PPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKGKEKLGRWKKIN 227 PPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKGKEKLGRWKKIN Sbjct: 181 PPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKGKEKLGRWKKIN 227 >6MRO-A nrPDB Length = 194 Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 5/130 (3%) Query: 46 PWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKAN 105 PWD P L+++ + GRAL GCG G + + +A V G+D+++ A++ A Sbjct: 12 PWDIDHPQPAFQALIESGEIRPGRALDIGCGRGENAIMLAKNGCDVTGIDLAKRAISDAK 71 Query: 106 ETYGSSPKAEYFSFVKEDVFTWRPT---ELFDLIFDYVFFCAIEPEMRPAWAKSMYELLK 162 + + +F+ +V + FD++ D F I E R + + ++++LK Sbjct: 72 AK--AIERHVKVNFIVGNVLEMDQLFTEDEFDIVIDSGLFHVITDEERLLFTRHVHKVLK 129 Query: 163 PDGELITLMY 172 G+ L + Sbjct: 130 EGGKYFMLCF 139 >4NEC-A nrPDB Length = 264 Score = 47.0 bits (110), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 4/119 (3%) Query: 46 PWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKAN 105 PWD G P V L + + L G L GCG G D + +A V GLD+S +A++ A Sbjct: 40 PWDIGAPQPAYVAL-EKAGLIQGAVLDAGCGTGEDALHLAGLGYAVTGLDLSPTAISVAR 98 Query: 106 ETYGSSPKAEYFSFVKE-DVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKP 163 + + F D+ W E FD + D E + A+A +++ +P Sbjct: 99 DKADARGLGAVFEVADALDLTGWE--ERFDTVIDSGLAHTFEGDRLRAYATALHRACRP 155 >3MGG-A nrPDB Length = 276 Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 8/114 (7%) Query: 61 DTSSLPLGRALVPGCGGGHDVVAMA--SPERFVVGLDISESALAKANETYGSSPKAEYFS 118 DT P + L GCG G V +A +P+ + +DIS +L KA E + + Sbjct: 32 DTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNG-IKNVK 90 Query: 119 FVKEDVFTWRPTELFDLIFDYVFFC-AIEPEMRPAWA-KSMYELLKPDGELITL 170 F++ ++F+ P E D FD++F C +E P A KS+ ++LKP G + + Sbjct: 91 FLQANIFSL-PFE--DSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVI 141 >2H11-A nrPDB Length = 232 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 53/193 (27%), Positives = 77/193 (39%), Gaps = 31/193 (16%) Query: 30 TVEEGGWEKCWEEEITPWDQGRATPLIVHLVDT-----SSLPLGRALVPGCGGGHDVVAM 84 T+EE W+ W T + Q + L+ +DT S L R P CG ++ Sbjct: 12 TLEE--WQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGKSGL---RVFFPLCGKAVEMKWF 66 Query: 85 ASPERFVVGLDISESAL----AKANETYGSSPKAEY------------FSFVKEDVFTWR 128 A VVG++ISE + + N +Y P E S +F Sbjct: 67 ADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKVFKSSSGNISLYCCSIFDLP 126 Query: 129 PTEL--FDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGE--LITLMYPITDHVGGPPYK 184 T + FD+I+D AI P R +A +M+ LL + L L Y T H GPP+ Sbjct: 127 RTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQYLLCVLSYDPTKH-PGPPFY 185 Query: 185 VDVSTFEEVLVPI 197 V + E + I Sbjct: 186 VPHAEIERLFGKI 198 >3OFK-A nrPDB Length = 216 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 8/131 (6%) Query: 40 WEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISES 99 W + P+++ R T L+ + SS + L GC G +A + + +D+ Sbjct: 27 WRLDDNPFERERHTQLL--RLSLSSGAVSNGLEIGCAAGAFTEKLAPHCKRLTVIDVMPR 84 Query: 100 ALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIF--DYVFFCAIEPEMRPAWAKSM 157 A+ +A + + + + S+ D+ + ELFDLI + +++ +MR A +M Sbjct: 85 AIGRACQ---RTKRWSHISWAATDILQFSTAELFDLIVVAEVLYYLEDMTQMRTA-IDNM 140 Query: 158 YELLKPDGELI 168 ++L P G L+ Sbjct: 141 VKMLAPGGHLV 151 >1PJZ-A nrPDB Length = 203 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 16/145 (11%) Query: 65 LPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSP----KAEYFSFV 120 +P R LVP CG D+ ++ VVG ++SE+A+ + G P + ++ + Sbjct: 21 VPGARVLVPLCGKSQDMSWLSGQGYHVVGAELSEAAVERYFTERGEQPHITSQGDFKVYA 80 Query: 121 KEDVFTW---------RPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELL--KPDGELIT 169 + W R +D A+ +MR + + + L+ G LIT Sbjct: 81 APGIEIWCGDFFALTARDIGHCAAFYDRAAMIALPADMRERYVQHLEALMPQACSGLLIT 140 Query: 170 LMYPITDHVGGPPYKVDVSTFEEVL 194 L Y + GPP+ V + V+ Sbjct: 141 LEYD-QALLEGPPFSVPQTWLHRVM 164 >4FGZ-A nrPDB Length = 266 Score = 35.4 bits (80), Expect = 0.019, Method: Compositional matrix adjust. Identities = 37/145 (25%), Positives = 56/145 (38%), Gaps = 22/145 (15%) Query: 73 PGCGGGHDVVAMASPERF---VVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR- 128 G GGG M E++ G+DI + + ANE + K F D+ T Sbjct: 64 SGLGGG----CMYINEKYGAHTHGIDICSNIVNMANERVSGNNK---IIFEANDILTKEF 116 Query: 129 PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPIT----------DHV 178 P FDLI+ + E + + Y+ LKP G L+ Y T ++V Sbjct: 117 PENNFDLIYSRDAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYV 176 Query: 179 GGPPYK-VDVSTFEEVLVPIGFKAV 202 Y + V + ++L FK V Sbjct: 177 KQRKYTLITVEEYADILTACNFKNV 201 >5WP5-A nrPDB Length = 491 Score = 35.4 bits (80), Expect = 0.021, Method: Compositional matrix adjust. Identities = 37/152 (24%), Positives = 66/152 (43%), Gaps = 14/152 (9%) Query: 66 PLGRALVPGCG-GGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 P + L GCG GG D + + VVG+D+S + ++ A E + F Sbjct: 282 PGQKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALERAIGLKCSVEFEVADCTT 341 Query: 125 FTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMY---------PIT 175 T+ P FD+I+ I+ +PA ++ ++ LKP G+++ Y Sbjct: 342 KTY-PDNSFDVIYSRDTILHIQD--KPALFRTFFKWLKPGGKVLITDYCRSAETPSPEFA 398 Query: 176 DHVGGPPYKV-DVSTFEEVLVPIGFKAVSVEE 206 +++ Y + DV + ++L GF V E+ Sbjct: 399 EYIKQRGYDLHDVQAYGQMLKDAGFDDVIAED 430 >3BGI-A nrPDB Length = 260 Score = 34.7 bits (78), Expect = 0.039, Method: Compositional matrix adjust. Identities = 45/175 (25%), Positives = 68/175 (38%), Gaps = 29/175 (16%) Query: 36 WEKCWEEEITPWDQGRATPLIVHLVDT-----SSLPLGRALVPGCGGGHDVVAMASPERF 90 W++ W + Q + L+ +DT S L R P CG ++ A Sbjct: 44 WKEKWVTRHISFHQEQGHQLLKKHLDTFLKGQSGL---RVFFPLCGKAIEMKWFADRGHT 100 Query: 91 VVGLDISESAL----AKANETYGSSPKAEY------------FSFVKEDVFTWRPTEL-- 132 VVG++ISE + A+ N +Y P AE S +F + Sbjct: 101 VVGVEISEIGIREFFAEQNLSYTEEPLAEIAGAKVFKSSSGSISLYCCSIFDLPRANIGK 160 Query: 133 FDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELI--TLMYPITDHVGGPPYKV 185 FD I+D AI P +A + LL+ + + + L Y T H GPP+ V Sbjct: 161 FDRIWDRGALVAINPGDHDRYADIILSLLRKEFQYLVAVLSYDPTKH-AGPPFYV 214 >5GM1-A nrPDB Length = 297 Score = 32.7 bits (73), Expect = 0.12, Method: Compositional matrix adjust. Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 25/167 (14%) Query: 58 HLVDTSSLPLGRALVP-GCGGGHDVVAMASPERF-VVGLDISESALAKANETYGSSPKAE 115 +L++T G+ L+ GCG G + A V G+ +S+ +A AN E Sbjct: 68 YLIETLDPKAGQHLLDIGCGTGRTALKAARQRGIAVTGVAVSKEQIAAANRLAAGHGLTE 127 Query: 116 YFSFVKEDVFTWRPTELFDLIFDYVFFCA--IEPEMRPAWAKSMYE---LLKPDGELITL 170 +F D P E D F CA IE AK++ E +LKP G+L+ L Sbjct: 128 RLTFEVADAMRL-PYE------DESFDCAWAIESLCHMDRAKALGEAWRVLKPGGDLLVL 180 Query: 171 MYPITDHVGGPP-------YKVDV----STFEEVLVPIGFKAVSVEE 206 +T+ + P Y +V F +++ GF +S+++ Sbjct: 181 ESVVTEELTEPETALFETLYAANVPPRLGEFFDIVSGAGFHTLSLKD 227 >3SM3-A nrPDB Length = 235 Score = 32.3 bits (72), Expect = 0.19, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 12/103 (11%) Query: 74 GCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSP--------KAEYFSFVKEDVF 125 GCG G + +AS V G+DI+ A+ A ET SP KAE F Sbjct: 38 GCGSGKISLELASKGYSVTGIDINSEAIRLA-ETAARSPGLNQKTGGKAE-FKVENASSL 95 Query: 126 TWRPTELFDLIFDYVFFCAI-EPEMRPAWAKSMYELLKPDGEL 167 ++ + FD F ++ +P+ R K ++ +LKP L Sbjct: 96 SFHDSS-FDFAVMQAFLTSVPDPKERSRIIKEVFRVLKPGAYL 137 >3L8D-A nrPDB Length = 242 Score = 32.0 bits (71), Expect = 0.20, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 5/78 (6%) Query: 47 WDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANE 106 WD G + I+ + L GCG G+ ++ VG+DISE + K E Sbjct: 35 WDSG-SRSTIIPFFEQYVKKEAEVLDVGCGDGYGTYKLSRTGYKAVGVDISEVMIQKGKE 93 Query: 107 TYGSSPKAEYFSFVKEDV 124 G P SF+K D+ Sbjct: 94 R-GEGPD---LSFIKGDL 107 >3M70-A nrPDB Length = 286 Score = 31.6 bits (70), Expect = 0.27, Method: Compositional matrix adjust. Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 2/113 (1%) Query: 69 RALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 + L GCG G + + ++ V D +E+++A NET + S D+ Sbjct: 123 KVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNET--KEKENLNISTALYDINAAN 180 Query: 129 PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGP 181 E +D I V F + E P+ K+M E G + + TD V P Sbjct: 181 IQENYDFIVSTVVFMFLNRERVPSIIKNMKEHTNVGGYNLIVAAMSTDDVPCP 233 >2P35-A nrPDB Length = 259 Score = 31.2 bits (69), Expect = 0.38, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 15/87 (17%) Query: 63 SSLPLGRALVP---GCGGGHDVVAMASPERF----VVGLDISESALAKANETYGSSPKAE 115 + +PL R L GCG G+ + +R+ + G+D + L KA + ++ Sbjct: 27 AQVPLERVLNGYDLGCGPGNSTELLT--DRYGVNVITGIDSDDDMLEKAADRLPNT---- 80 Query: 116 YFSFVKEDVFTWRPTELFDLIFDYVFF 142 +F K D+ TW+P + DL++ F Sbjct: 81 --NFGKADLATWKPAQKADLLYANAVF 105 >4QDJ-A nrPDB Length = 238 Score = 30.4 bits (67), Expect = 0.57, Method: Compositional matrix adjust. Identities = 27/107 (25%), Positives = 42/107 (39%), Gaps = 16/107 (14%) Query: 41 EEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESA 100 +++I Q ++ LV +LP GCG G + +A V G DISE Sbjct: 37 QKDIRVGHQQTVDSVVAWLVADGNLPGLLVCDAGCGVGSLSIPLAQAGALVYGSDISEKM 96 Query: 101 LAKANE------TYGSSPK----------AEYFSFVKEDVFTWRPTE 131 + +A + YG+ P +Y + + DV PTE Sbjct: 97 VGEAQQKAQEVLAYGNQPTFMTQDLAQLGGKYDTVICLDVLIHYPTE 143 >5JE5-A nrPDB Length = 247 Score = 30.4 bits (67), Expect = 0.71, Method: Compositional matrix adjust. Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Query: 91 VVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLI-FDYVFFCAIEPEM 149 VVG+DISE + A E S + F DV P FDL+ ++F A E Sbjct: 67 VVGVDISEKMIELAREE--SRKYGDPLEFHVRDVANMEPLGQFDLVNAAWLFNYADSVEN 124 Query: 150 RPAWAKSMYELLKPDGELIT 169 K + LKPDG+L+ Sbjct: 125 LRKMFKVVRASLKPDGKLVA 144 >4KRI-A nrPDB Length = 433 Score = 30.0 bits (66), Expect = 0.95, Method: Compositional matrix adjust. Identities = 37/148 (25%), Positives = 58/148 (39%), Gaps = 25/148 (16%) Query: 74 GCGGGHDVVAMASPERF---VVGLDISESALAKANETYGSSPKAEY-FSFVKEDVFTWRP 129 G GGG A + F V G+D+S + LA A E A ++ + + P Sbjct: 232 GIGGG----ARQAASEFGLQVHGVDLSTNMLAVALERVHKEKDARVTYAVCDACEYEFEP 287 Query: 130 TELFDLIFDYVFF--CAIEPEMRPAWAKSMYELLKPDGELITLMYPI---------TDHV 178 FDYVF C + +Y LKP G+++ MY + ++V Sbjct: 288 NS-----FDYVFSRDCIQHIKDTDKLFSRIYRALKPGGKVLITMYGVGHGTLSESFKEYV 342 Query: 179 GGPPYKV-DVSTFEEVLVPIGFKAVSVE 205 Y + ++ EE+ GF + VE Sbjct: 343 SQRQYYLKNLEQIEEIAKKTGFIDIEVE 370 >4INE-A nrPDB Length = 454 Score = 29.6 bits (65), Expect = 1.00, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 15/105 (14%) Query: 74 GCGGGHDVVAMASPERF---VVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPT 130 G GGG VA + F V G+D+S + LA A E + VK + Sbjct: 251 GIGGGARQVA----DEFGVHVHGIDLSSNMLAIALERLHEEKDSR----VKYSITDALVY 302 Query: 131 ELFDLIFDYVFF--CAIE-PEMRPAWAKSMYELLKPDGELITLMY 172 + D FDYVF C P+ +++ +Y+ LKP G+++ MY Sbjct: 303 QFEDNSFDYVFSRDCIQHIPDTEKLFSR-IYKALKPGGKVLITMY 346 >4RVS-A nrPDB Length = 329 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Query: 101 LAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAI 145 L A Y + P +F+ E+ F+WR ELFD I + A+ Sbjct: 257 LNAAGSVYLTRPSLFHFTRTGEE-FSWRAAELFDAIGNEAITVAV 300 >2EEC-A nrPDB Length = 125 Score = 28.1 bits (61), Expect = 2.9, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 20/38 (52%) Query: 151 PAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDVS 188 P K MY + P LI++ Y +H+ G P+K V+ Sbjct: 72 PEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVT 109 >3CCF-A nrPDB Length = 279 Score = 27.7 bits (60), Expect = 4.7, Method: Compositional matrix adjust. Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 10/97 (10%) Query: 74 GCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELF 133 GCG G +A V+G D + + + KA + Y + F D +R + Sbjct: 65 GCGTGQLTEKIAQSGAEVLGTDNAATMIEKARQNY------PHLHFDVADARNFRVDKPL 118 Query: 134 DLIFDYVFFCAI-EPEMRPAWAKSMYELLKPDGELIT 169 D +F + EPE A S+++ LK G + Sbjct: 119 DAVFSNAMLHWVKEPEAAIA---SIHQALKSGGRFVA 152 >6ED3-A nrPDB Length = 848 Score = 27.3 bits (59), Expect = 5.1, Method: Composition-based stats. Identities = 15/36 (41%), Positives = 22/36 (61%) Query: 86 SPERFVVGLDISESALAKANETYGSSPKAEYFSFVK 121 S E +VGL +S +AK +G+SP+A +FVK Sbjct: 107 STEHVMVGLATGDSDVAKLLTGHGASPQALREAFVK 142 >3OU6-A nrPDB Length = 218 Score = 26.9 bits (58), Expect = 6.5, Method: Compositional matrix adjust. Identities = 24/104 (23%), Positives = 46/104 (44%), Gaps = 8/104 (7%) Query: 80 DVVAMASPE----RFVVGLDISESALAKANETYGSSPK--AEYFSFVKEDVFTWRPTELF 133 DV+ +AS R + GL +AL + E + + + F ++D+F W P + Sbjct: 49 DVLELASGTGYWTRHLSGLADRVTALDGSAEMIAEAGRHGLDNVEFRQQDLFDWTPDRQW 108 Query: 134 DLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDH 177 D +F + + + A+ +S+ + P G + +TDH Sbjct: 109 DAVFFAHWLAHVPDDRFEAFWESVRSAVAPGG--VVEFVDVTDH 150 >3SNO-A nrPDB Length = 315 Score = 26.9 bits (58), Expect = 7.6, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 22/35 (62%), Gaps = 3/35 (8%) Query: 11 SNGGNVIPTPEEVATFLHKTVEEGGWEKCWEEEIT 45 S GG+++P + A F H T E GW +C E++++ Sbjct: 236 SPGGDILPGTTQAALFAHAT--EKGW-RCKEKDLS 267 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3LCC-A nrPDB 368 e-103 2H11-A nrPDB 190 4e-49 6MRO-A nrPDB 162 1e-40 3OFK-A nrPDB 140 5e-34 4NEC-A nrPDB 134 4e-32 3MGG-A nrPDB 104 5e-23 Sequences not found previously or not previously below threshold: 3BGI-A nrPDB 147 4e-36 3BUS-A nrPDB 69 2e-12 1PJZ-A nrPDB 63 1e-10 5WP5-A nrPDB 61 4e-10 3D2L-A nrPDB 61 5e-10 3M70-A nrPDB 60 9e-10 3BKW-A nrPDB 59 1e-09 4PNE-A nrPDB 59 2e-09 5GM1-A nrPDB 59 2e-09 4HTF-A nrPDB 58 4e-09 2I6G-A nrPDB 57 6e-09 3GDH-A nrPDB 56 1e-08 3EGI-A nrPDB 56 1e-08 3SM3-A nrPDB 56 1e-08 5WP4-A nrPDB 56 1e-08 3OU6-A nrPDB 54 5e-08 3CCF-A nrPDB 52 1e-07 3L8D-A nrPDB 52 2e-07 5BP9-A nrPDB 52 2e-07 5JE5-A nrPDB 52 2e-07 5U19-A nrPDB 52 3e-07 3E23-A nrPDB 50 7e-07 4X3Q-A nrPDB 50 8e-07 2XVM-A nrPDB 50 8e-07 4KRI-A nrPDB 49 2e-06 5MGZ-A nrPDB 48 3e-06 4HGY-A nrPDB 47 6e-06 5EVJ-A nrPDB 47 7e-06 4AZW-A nrPDB 47 7e-06 4AZV-A nrPDB 47 7e-06 4KDR-A nrPDB 47 7e-06 4KDC-A nrPDB 47 7e-06 1RI1-A nrPDB 46 9e-06 2GLU-A nrPDB 46 1e-05 5F8E-A nrPDB 46 1e-05 1L3B-A nrPDB 46 1e-05 1VL5-A nrPDB 46 1e-05 3SVZ-A nrPDB 46 1e-05 4GEK-A nrPDB 46 1e-05 5M58-A nrPDB 46 2e-05 2AS0-A nrPDB 46 2e-05 3HNR-A nrPDB 45 2e-05 6CU3-A nrPDB 45 3e-05 4QDJ-A nrPDB 45 3e-05 1WXW-A nrPDB 45 3e-05 1D2C-A nrPDB 45 3e-05 4ISC-A nrPDB 45 3e-05 4IWN-A nrPDB 45 3e-05 5BSZ-A nrPDB 45 3e-05 4INE-A nrPDB 45 3e-05 3TM5-A nrPDB 45 3e-05 4FS8-A nrPDB 44 4e-05 5BXY-A nrPDB 44 5e-05 2PJD-A nrPDB 44 5e-05 1Y8C-A nrPDB 44 7e-05 1P91-A nrPDB 44 7e-05 4IV8-A nrPDB 43 9e-05 6BQC-A nrPDB 43 1e-04 3DMF-A nrPDB 42 1e-04 4MWZ-A nrPDB 42 2e-04 4DZR-A nrPDB 42 2e-04 1TPY-A nrPDB 42 3e-04 4KIC-A nrPDB 42 3e-04 3GU3-A nrPDB 41 3e-04 3I9F-A nrPDB 41 6e-04 1NKV-A nrPDB 41 6e-04 3CJR-A nrPDB 40 7e-04 4FGZ-A nrPDB 39 0.001 2B3T-A nrPDB 39 0.002 1R74-A nrPDB 39 0.002 5BP7-A nrPDB 39 0.002 2AVN-A nrPDB 38 0.003 1UWV-A nrPDB 38 0.003 1KP9-A nrPDB 38 0.003 1G6Q-1 nrPDB 38 0.003 5H02-A nrPDB 38 0.003 4F86-A nrPDB 38 0.003 3LBF-A nrPDB 38 0.003 6G4W-q nrPDB 37 0.004 4RYL-A nrPDB 37 0.005 3VC2-A nrPDB 37 0.006 1DUS-A nrPDB 37 0.007 3BXO-A nrPDB 37 0.007 2IH5-A nrPDB 37 0.008 3LDU-A nrPDB 37 0.009 2H1R-A nrPDB 36 0.010 5E2B-A nrPDB 36 0.011 1F3L-A nrPDB 36 0.014 2YXD-A nrPDB 36 0.016 4QNV-A nrPDB 36 0.016 3JWJ-A nrPDB 36 0.019 3EGE-A nrPDB 36 0.019 4A6D-A nrPDB 35 0.029 3V4C-A nrPDB 35 0.036 2VS1-A nrPDB 34 0.037 1WS6-A nrPDB 34 0.045 6M83-A nrPDB 34 0.051 4P7C-A nrPDB 34 0.051 4KRG-A nrPDB 34 0.053 1XDU-A nrPDB 34 0.054 5WMM-A nrPDB 34 0.068 5IS8-A nrPDB 34 0.070 4IKP-A nrPDB 34 0.070 3B3J-A nrPDB 34 0.070 4QTT-B nrPDB 34 0.070 1VLM-A nrPDB 34 0.073 3MCZ-A nrPDB 33 0.088 4HG2-A nrPDB 33 0.090 3GRV-A nrPDB 33 0.091 3FYD-A nrPDB 33 0.091 3R0Q-C nrPDB 33 0.092 4DCM-A nrPDB 33 0.096 1QAM-A nrPDB 33 0.11 1L1E-A nrPDB 33 0.12 3HTX-A nrPDB 33 0.13 6GKZ-A nrPDB 32 0.20 5Y4R-A nrPDB 32 0.25 3BKX-A nrPDB 32 0.25 1YUB-A nrPDB 32 0.26 5XJ2-A nrPDB 31 0.34 2ZIG-A nrPDB 31 0.35 1XTP-A nrPDB 31 0.46 2PBF-A nrPDB 31 0.48 2X1E-A nrPDB 30 0.61 5X62-A nrPDB 30 0.66 3HEM-A nrPDB 30 0.66 3MTI-A nrPDB 30 0.72 1WG8-A nrPDB 30 0.90 3CO8-A nrPDB 30 1.1 6IFV-A nrPDB 29 1.3 3B5I-A nrPDB 29 1.5 3JWI-A nrPDB 29 1.5 3CKK-A nrPDB 29 1.5 2B5D-X nrPDB 29 1.6 6IFX-A nrPDB 29 1.8 4PB5-A nrPDB 29 1.9 1NVM-B nrPDB 29 2.0 2YVL-A nrPDB 29 2.1 2EEC-A nrPDB 29 2.1 4RVG-A nrPDB 29 2.2 3FUV-A nrPDB 29 2.2 1VKN-A nrPDB 29 2.4 5LV5-A nrPDB 29 2.6 6DCC-A nrPDB 28 3.0 5EHG-A nrPDB 28 3.2 4V0R-A nrPDB 28 3.8 1ZEJ-A nrPDB 28 3.8 1RJ5-A nrPDB 27 4.9 1VKM-A nrPDB 27 5.0 3HLK-A nrPDB 27 5.9 5E9J-A nrPDB 27 7.2 3BGV-A nrPDB 27 7.2 3HXK-A nrPDB 27 9.1 3DC8-A nrPDB 27 9.5 >3LCC-A nrPDB Length = 235 Score = 368 bits (945), Expect = e-103, Method: Composition-based stats. Identities = 227/227 (100%), Positives = 227/227 (100%) Query: 1 MAEEQQNSDQSNGGNVIPTPEEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLV 60 MAEEQQNSDQSNGGNVIPTPEEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLV Sbjct: 1 MAEEQQNSDQSNGGNVIPTPEEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLV 60 Query: 61 DTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFV 120 DTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFV Sbjct: 61 DTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFV 120 Query: 121 KEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGG 180 KEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGG Sbjct: 121 KEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGG 180 Query: 181 PPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKGKEKLGRWKKIN 227 PPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKGKEKLGRWKKIN Sbjct: 181 PPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKGKEKLGRWKKIN 227 >2H11-A nrPDB Length = 232 Score = 190 bits (483), Expect = 4e-49, Method: Composition-based stats. Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 25/190 (13%) Query: 30 TVEEGGWEKCWEEEITPWDQGRATPLIVHLVDT--SSLPLGRALVPGCGGGHDVVAMASP 87 T+EE W+ W T + Q + L+ +DT R P CG ++ A Sbjct: 12 TLEE--WQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGKSGLRVFFPLCGKAVEMKWFADR 69 Query: 88 ERFVVGLDISESAL----AKANETYGSSPKAE------------YFSFVKEDVFTWRPTE 131 VVG++ISE + + N +Y P E S +F T Sbjct: 70 GHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKVFKSSSGNISLYCCSIFDLPRTN 129 Query: 132 L--FDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGE--LITLMYPITDHVGGPPYKVDV 187 + FD+I+D AI P R +A +M+ LL + L L Y T H GPP+ V Sbjct: 130 IGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQYLLCVLSYDPTKH-PGPPFYVPH 188 Query: 188 STFEEVLVPI 197 + E + I Sbjct: 189 AEIERLFGKI 198 >6MRO-A nrPDB Length = 194 Score = 162 bits (409), Expect = 1e-40, Method: Composition-based stats. Identities = 38/168 (22%), Positives = 75/168 (44%), Gaps = 11/168 (6%) Query: 36 WEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLD 95 W++ ++ PWD P L+++ + GRAL GCG G + + +A V G+D Sbjct: 3 WDEVYK-GTPPWDIDHPQPAFQALIESGEIRPGRALDIGCGRGENAIMLAKNGCDVTGID 61 Query: 96 ISESALAKANETYGSSPKAEYFSFVKEDVFTWRPT---ELFDLIFDYVFFCAIEPEMRPA 152 +++ A++ A + + +F+ +V + FD++ D F I E R Sbjct: 62 LAKRAISDAKAK--AIERHVKVNFIVGNVLEMDQLFTEDEFDIVIDSGLFHVITDEERLL 119 Query: 153 WAKSMYELLKPDGELITLMYPITDHVGGP---PYKVDVSTFEEVLVPI 197 + + ++++LK G+ L + +D G P + + E P+ Sbjct: 120 FTRHVHKVLKEGGKYFMLCF--SDKEPGEYELPRRASKAEIESTFSPL 165 >3BGI-A nrPDB Length = 260 Score = 147 bits (371), Expect = 4e-36, Method: Composition-based stats. Identities = 45/188 (23%), Positives = 73/188 (38%), Gaps = 25/188 (13%) Query: 30 TVEEGGWEKCWEEEITPWDQGRATPLIVHLVDT--SSLPLGRALVPGCGGGHDVVAMASP 87 T+E+ W++ W + Q + L+ +DT R P CG ++ A Sbjct: 40 TLED--WKEKWVTRHISFHQEQGHQLLKKHLDTFLKGQSGLRVFFPLCGKAIEMKWFADR 97 Query: 88 ERFVVGLDISESAL----AKANETYGSSPKAEY------------FSFVKEDVFTWRPTE 131 VVG++ISE + A+ N +Y P AE S +F Sbjct: 98 GHTVVGVEISEIGIREFFAEQNLSYTEEPLAEIAGAKVFKSSSGSISLYCCSIFDLPRAN 157 Query: 132 L--FDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELI--TLMYPITDHVGGPPYKVDV 187 + FD I+D AI P +A + LL+ + + + L Y T H GPP+ V Sbjct: 158 IGKFDRIWDRGALVAINPGDHDRYADIILSLLRKEFQYLVAVLSYDPTKHA-GPPFYVPS 216 Query: 188 STFEEVLV 195 + + + Sbjct: 217 AELKRLFG 224 >3OFK-A nrPDB Length = 216 Score = 140 bits (352), Expect = 5e-34, Method: Composition-based stats. Identities = 33/144 (22%), Positives = 68/144 (47%), Gaps = 9/144 (6%) Query: 28 HKTVE-EGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMAS 86 ++++E E + W + P+++ R T L+ + SS + L GC G +A Sbjct: 14 YQSLERELANDDPWRLDDNPFERERHTQLL--RLSLSSGAVSNGLEIGCAAGAFTEKLAP 71 Query: 87 PERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIF--DYVFFCA 144 + + +D+ A+ +A + + + + S+ D+ + ELFDLI + +++ Sbjct: 72 HCKRLTVIDVMPRAIGRACQ---RTKRWSHISWAATDILQFSTAELFDLIVVAEVLYYLE 128 Query: 145 IEPEMRPAWAKSMYELLKPDGELI 168 +MR A +M ++L P G L+ Sbjct: 129 DMTQMRTA-IDNMVKMLAPGGHLV 151 >4NEC-A nrPDB Length = 264 Score = 134 bits (336), Expect = 4e-32, Method: Composition-based stats. Identities = 35/127 (27%), Positives = 53/127 (41%), Gaps = 4/127 (3%) Query: 46 PWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKAN 105 PWD G P V L + + L G L GCG G D + +A V GLD+S +A++ A Sbjct: 40 PWDIGAPQPAYVAL-EKAGLIQGAVLDAGCGTGEDALHLAGLGYAVTGLDLSPTAISVAR 98 Query: 106 ETYGSSPKAEYFSFVKE-DVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPD 164 + + F D+ W E FD + D E + A+A +++ +P Sbjct: 99 DKADARGLGAVFEVADALDLTGWE--ERFDTVIDSGLAHTFEGDRLRAYATALHRACRPG 156 Query: 165 GELITLM 171 L Sbjct: 157 AVAHILS 163 >3MGG-A nrPDB Length = 276 Score = 104 bits (258), Expect = 5e-23, Method: Composition-based stats. Identities = 36/116 (31%), Positives = 58/116 (50%), Gaps = 8/116 (6%) Query: 59 LVDTSSLPLGRALVPGCGGGHDVVAMA--SPERFVVGLDISESALAKANETYGSSPKAEY 116 DT P + L GCG G V +A +P+ + +DIS +L KA E + + Sbjct: 30 HHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGI-KN 88 Query: 117 FSFVKEDVFTWRPTELFDLIFDYVFFC-AIEPEMRPAWA-KSMYELLKPDGELITL 170 F++ ++F+ P E D FD++F C +E P A KS+ ++LKP G + + Sbjct: 89 VKFLQANIFSL-PFE--DSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVI 141 >3BUS-A nrPDB Length = 273 Score = 68.6 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 17/168 (10%) Query: 18 PTPEEV-----------ATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLP 66 PTPEEV A + + G WE + R T ++ L+D S Sbjct: 4 PTPEEVRQMYDDFTDPFARIWGENLHFGYWEDAGADVSVDDATDRLTDEMIALLDVRS-- 61 Query: 67 LGRALVPGCGGGHDVVAMAS-PERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVF 125 R L GCG G V +A+ + V G+ IS + +AN ++ A +F D Sbjct: 62 GDRVLDVGCGIGKPAVRLATARDVRVTGISISRPQVNQANARATAAGLANRVTFSYADAM 121 Query: 126 TWRPTEL-FDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMY 172 + FD ++ P+ A + M +L+P G + + Sbjct: 122 DLPFEDASFDAVWALESLHH-MPDRGRA-LREMARVLRPGGTVAIADF 167 >1PJZ-A nrPDB Length = 203 Score = 62.9 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 34/145 (23%), Positives = 56/145 (38%), Gaps = 16/145 (11%) Query: 65 LPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEY-------- 116 +P R LVP CG D+ ++ VVG ++SE+A+ + G P Sbjct: 21 VPGARVLVPLCGKSQDMSWLSGQGYHVVGAELSEAAVERYFTERGEQPHITSQGDFKVYA 80 Query: 117 ---FSFVKEDVFTWRPTELFD--LIFDYVFFCAIEPEMRPAWAKSMYELLKP--DGELIT 169 D F ++ +D A+ +MR + + + L+ G LIT Sbjct: 81 APGIEIWCGDFFALTARDIGHCAAFYDRAAMIALPADMRERYVQHLEALMPQACSGLLIT 140 Query: 170 LMYPITDHVGGPPYKVDVSTFEEVL 194 L Y + GPP+ V + V+ Sbjct: 141 LEYD-QALLEGPPFSVPQTWLHRVM 164 >5WP5-A nrPDB Length = 491 Score = 60.9 bits (146), Expect = 4e-10, Method: Composition-based stats. Identities = 40/165 (24%), Positives = 68/165 (41%), Gaps = 16/165 (9%) Query: 53 TPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASP-ERFVVGLDISESALAKANETYGSS 111 T V +D P + L GCG G MA + VVG+D+S + ++ A E Sbjct: 271 TKEFVAKMDLK--PGQKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALERAIGL 328 Query: 112 PKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLM 171 + F T+ P FD+I+ I + +PA ++ ++ LKP G+++ Sbjct: 329 KCSVEFEVADCTTKTY-PDNSFDVIYSRDTILHI--QDKPALFRTFFKWLKPGGKVLITD 385 Query: 172 YPITDHVGGPPY--KV--------DVSTFEEVLVPIGFKAVSVEE 206 Y + P + + DV + ++L GF V E+ Sbjct: 386 YCRSAETPSPEFAEYIKQRGYDLHDVQAYGQMLKDAGFDDVIAED 430 Score = 47.1 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 36/105 (34%), Gaps = 6/105 (5%) Query: 67 LGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFT 126 L G G G +A V+ LD ESA+ K + + F+ DV + Sbjct: 54 GKSVLELGAGIGRFTGELAQKAGEVIALDFIESAIQK---NESVNGHYKNIKFMCADVTS 110 Query: 127 WR---PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 DLIF + + A+ M +KP G + Sbjct: 111 PDLKIKDGSIDLIFSNWLLMYLSDKEVELMAERMIGWVKPGGYIF 155 >3D2L-A nrPDB Length = 243 Score = 60.5 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 47/129 (36%), Gaps = 3/129 (2%) Query: 49 QGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETY 108 Q P V V P R GCG G + +A V G+D+SE L A E Sbjct: 16 QDVPYPEWVAWVLEQVEPGKRIADIGCGTGTATLLLADH-YEVTGVDLSEEMLEIAQEKA 74 Query: 109 GSSPKAEYFSFVKEDVFTWR-PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGEL 167 + + F P + ++ D + + E +++ + S LL G+L Sbjct: 75 METNRHVDFWVQDMRELELPEPVDAITILCDSLNYLQTEADVKQTF-DSAARLLTDGGKL 133 Query: 168 ITLMYPITD 176 + ++ Sbjct: 134 LFDVHSPYK 142 >3M70-A nrPDB Length = 286 Score = 59.8 bits (143), Expect = 9e-10, Method: Composition-based stats. Identities = 31/128 (24%), Positives = 50/128 (39%), Gaps = 3/128 (2%) Query: 65 LPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 + + L GCG G + + ++ V D +E+++A NET S D+ Sbjct: 119 ISPCKVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNETKEKENL--NISTALYDI 176 Query: 125 FTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGP-PY 183 E +D I V F + E P+ K+M E G + + TD V P P+ Sbjct: 177 NAANIQENYDFIVSTVVFMFLNRERVPSIIKNMKEHTNVGGYNLIVAAMSTDDVPCPLPF 236 Query: 184 KVDVSTFE 191 + E Sbjct: 237 SFTFAENE 244 >3BKW-A nrPDB Length = 243 Score = 59.4 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 44/130 (33%), Gaps = 8/130 (6%) Query: 54 PLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERF-VVGLDISESALAKANETYGSSP 112 P + ++ R + GCG G V+GLD+SE LA+A + Sbjct: 33 PALRAMLPEVGGL--RIVDLGCGFGWFCRWAHEHGASYVLGLDLSEKMLARARAAGPDTG 90 Query: 113 KAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMY 172 + D + FDL + + +E R +++++ L P G + Sbjct: 91 IT--YERADLDKLHLPQ-DSFDLAYSSLALHYVEDVARLF--RTVHQALSPGGHFVFSTE 145 Query: 173 PITDHVGGPP 182 P Sbjct: 146 HPIYMAPARP 155 >4PNE-A nrPDB Length = 302 Score = 59.0 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 32/146 (21%), Positives = 52/146 (35%), Gaps = 5/146 (3%) Query: 40 WEEEITPWDQGRATPLIVHLVDTSSLPLG-RALVPGCGGGHDVVAMA-SPERFVVGLDIS 97 WE + Q A L + + + L G R L GCG G + +A + G+ +S Sbjct: 65 WENDGRASWQQAADRLTDLVAERTVLDGGVRLLDVGCGTGQPALRVARDNAIQITGITVS 124 Query: 98 ESALAKANETYGSSPKAEYFSFVKEDVFTWR-PTELFDLIFDYVFFCAIEPEMRPAWAKS 156 + +A A + + F D + P FD + + R + Sbjct: 125 QVQVAIAADCARERGLSHRVDFSCVDAMSLPYPDNAFDAAWAMQSLLEMSEPDRA--IRE 182 Query: 157 MYELLKPDGELITLMYPITDHVGGPP 182 + +LKP G L + GG P Sbjct: 183 ILRVLKPGGILGVTEVVKREAGGGMP 208 >5GM1-A nrPDB Length = 297 Score = 59.0 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 6/126 (4%) Query: 59 LVDTSSLPLGR-ALVPGCGGGHDVVAMA-SPERFVVGLDISESALAKANETYGSSPKAEY 116 L++T G+ L GCG G + A V G+ +S+ +A AN E Sbjct: 69 LIETLDPKAGQHLLDIGCGTGRTALKAARQRGIAVTGVAVSKEQIAAANRLAAGHGLTER 128 Query: 117 FSFVKEDVFTWR-PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPIT 175 +F D E FD + C R + +LKP G+L+ L +T Sbjct: 129 LTFEVADAMRLPYEDESFDCAWAIESLC---HMDRAKALGEAWRVLKPGGDLLVLESVVT 185 Query: 176 DHVGGP 181 + + P Sbjct: 186 EELTEP 191 >4HTF-A nrPDB Length = 285 Score = 57.8 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 44/122 (36%), Gaps = 4/122 (3%) Query: 54 PLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPK 113 + ++ R L G G G + MA V+ D+S + +A + + Sbjct: 56 QDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGV 115 Query: 114 AEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEP--EMRPAWAKSMYELLKPDGELITLM 171 ++ F+ + D + F A+ + ++++ +L+P G L + Sbjct: 116 SDNMQFIHCAAQDV--ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMF 173 Query: 172 YP 173 Y Sbjct: 174 YN 175 >2I6G-A nrPDB Length = 199 Score = 57.1 bits (136), Expect = 6e-09, Method: Composition-based stats. Identities = 26/136 (19%), Positives = 45/136 (33%), Gaps = 10/136 (7%) Query: 65 LPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 + GR L GCG G + + +A+ V D + +++A AE ++ D+ Sbjct: 30 VAPGRTLDLGCGNGRNSLYLAANGYDVTAWDKNPASMA----NLERIKAAEGLDNLQTDL 85 Query: 125 FTWRPTE---LFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVG-- 179 +D I V +E + P +M KP G + + T Sbjct: 86 VDLNTLTFDGEYDFILSTVVMMFLEAQTIPGLIANMQRCTKPGGYNLIVAAMDTPDFPCT 145 Query: 180 -GPPYKVDVSTFEEVL 194 G P+ Sbjct: 146 VGFPFAFKEGELRRYY 161 >3GDH-A nrPDB Length = 241 Score = 56.3 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 31/140 (22%), Positives = 53/140 (37%), Gaps = 6/140 (4%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRP 129 + CG G + + A V+ +DI +A A A+ F+ D Sbjct: 82 VVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEVYGIADKIEFICGDFLLLAS 141 Query: 130 TELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDG-ELITLMYPITDH-VGGPPYKVDV 187 D++F + P+ A + ++ PDG E+ L IT++ V P D+ Sbjct: 142 FLKADVVFLSPPWGG--PDYATAETFDIRTMMSPDGFEIFRLSKKITNNIVYFLPRNADI 199 Query: 188 STFEEVLVPIGFKAVSVEEN 207 + P G V +E+N Sbjct: 200 DQVASLAGPGG--QVEIEQN 217 >3EGI-A nrPDB Length = 206 Score = 56.3 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 31/140 (22%), Positives = 53/140 (37%), Gaps = 6/140 (4%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRP 129 + CG G + + A V+ +DI +A A A+ F+ D Sbjct: 47 VVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEVYGIADKIEFICGDFLLLAS 106 Query: 130 TELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDG-ELITLMYPITDH-VGGPPYKVDV 187 D++F + P+ A + ++ PDG E+ L IT++ V P D+ Sbjct: 107 FLKADVVFLSPPWGG--PDYATAETFDIRTMMSPDGFEIFRLSKKITNNIVYFLPRNADI 164 Query: 188 STFEEVLVPIGFKAVSVEEN 207 + P G V +E+N Sbjct: 165 DQVASLAGPGG--QVEIEQN 182 >3SM3-A nrPDB Length = 235 Score = 56.3 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 45/115 (39%), Gaps = 6/115 (5%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESAL----AKANETYGSSPKAEYFSFVKEDVF 125 L GCG G + +AS V G+DI+ A+ A + F E+ Sbjct: 34 ILDIGCGSGKISLELASKGYSVTGIDINSEAIRLAETAARSPGLNQKTGGKAEFKVENAS 93 Query: 126 TWRPTE-LFDLIFDYVFFCAI-EPEMRPAWAKSMYELLKPDGELITLMYPITDHV 178 + + FD F ++ +P+ R K ++ +LKP L + + H+ Sbjct: 94 SLSFHDSSFDFAVMQAFLTSVPDPKERSRIIKEVFRVLKPGAYLYLVEFGQNWHL 148 >5WP4-A nrPDB Length = 491 Score = 56.3 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 11/141 (7%) Query: 66 PLGRALVPGCGGGHDVVAMASP-ERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 P + L GCG G MA + VVG+D+S + ++ A E + F Sbjct: 282 PGQKVLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALERAIGLSCSVEFEVADCTT 341 Query: 125 FTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYK 184 + P FD+I+ I + +PA ++ ++ LKP G+++ I+D+ P K Sbjct: 342 KHY-PDNSFDVIYSRDTILHI--QDKPALFRTFFKWLKPGGKVL-----ISDYCRSP--K 391 Query: 185 VDVSTFEEVLVPIGFKAVSVE 205 + F E + G+ V+ Sbjct: 392 TPSAEFSEYIKQRGYDLHDVQ 412 >3OU6-A nrPDB Length = 218 Score = 54.0 bits (128), Expect = 5e-08, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 51/128 (39%), Gaps = 8/128 (6%) Query: 50 GRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYG 109 A P + + ++ G L G G+ ++ V LD S +A+A G Sbjct: 31 DSAAPAALERLRAGNIR-GDVLELASGTGYWTRHLSGLADRVTALDGSAEMIAEA----G 85 Query: 110 SSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 + F ++D+F W P +D +F + + + A+ +S+ + P G + Sbjct: 86 RHGL-DNVEFRQQDLFDWTPDRQWDAVFFAHWLAHVPDDRFEAFWESVRSAVAPGG--VV 142 Query: 170 LMYPITDH 177 +TDH Sbjct: 143 EFVDVTDH 150 >3CCF-A nrPDB Length = 279 Score = 52.5 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 48/134 (35%), Gaps = 13/134 (9%) Query: 36 WEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLD 95 W+ ++ + L+ L P L GCG G +A V+G D Sbjct: 30 WDATLYQDKHSFVWQYGEDLLQLLNPQ---PGEFILDLGCGTGQLTEKIAQSGAEVLGTD 86 Query: 96 ISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFC-AIEPEMRPAWA 154 + + + KA + Y + F D +R + D +F EPE A Sbjct: 87 NAATMIEKARQNYP------HLHFDVADARNFRVDKPLDAVFSNAMLHWVKEPE---AAI 137 Query: 155 KSMYELLKPDGELI 168 S+++ LK G + Sbjct: 138 ASIHQALKSGGRFV 151 >3L8D-A nrPDB Length = 242 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 41/186 (22%), Positives = 63/186 (33%), Gaps = 27/186 (14%) Query: 37 EKCWEEEITPWDQGRAT-------PLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPER 89 EK W+ W+Q I+ + L GCG G+ ++ Sbjct: 17 EKKWDSSAEFWNQNSQEMWDSGSRSTIIPFFEQYVKKEAEVLDVGCGDGYGTYKLSRTGY 76 Query: 90 FVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR-PTELFDLIFDYVFFCAIEPE 148 VG+DISE + K E + SF+K D+ + E F+ I ++E Sbjct: 77 KAVGVDISEVMIQKGKE----RGEGPDLSFIKGDLSSLPFENEQFEAIM---AINSLEWT 129 Query: 149 MRPAWA-KSMYELLKPDGELITLMYPIT---DHVGGPPYKVDVS--------TFEEVLVP 196 P A + +LK DG + T P FE+++ Sbjct: 130 EEPLRALNEIKRVLKSDGYACIAILGPTAKPRENSYPRLYGKDVVCNTMMPWEFEQLVKE 189 Query: 197 IGFKAV 202 GFK V Sbjct: 190 QGFKVV 195 >5BP9-A nrPDB Length = 281 Score = 52.1 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 44/243 (18%), Positives = 85/243 (34%), Gaps = 49/243 (20%) Query: 9 DQSNGGNVIPTPEE-----VATFLHKTVEEG--GWEKCWEEEITPWDQGRATPLIVHLVD 61 +QS +++P ++ +A F H+ + + ++E+ P Q + L++ Sbjct: 35 NQSMNTSLLPAEKDPMGAAIADFYHRQKADRLRVFSSQFDEDEIPVKQLFRKAGQMPLLE 94 Query: 62 TSSLPL--GRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSF 119 ++L + G L G G G +A+ + V +DIS ++ + Sbjct: 95 RTALAMATGTILDVGAGSGCHALALQESGKEVSAIDISPLSVEVMKLRGVKDAR------ 148 Query: 120 VKEDVFTWRPTELFDLI--FDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPIT-- 175 + ++F R FD I E P + + M +LL+PDG ++ + Sbjct: 149 -QVNLFDERFAATFDTILMLMNGSGIIGRLENMPLFFRKMKQLLRPDGCILMDSSDLRYL 207 Query: 176 --------------------------DHVGGPPY---KVDVSTFEEVLVPIGFKAVSVEE 206 + G P+ +D T GFKA ++E Sbjct: 208 FEDEDGSFLIDLAGDYYGEIDFRMQYKDIQGDPFDWLYIDFQTLSAYAADNGFKAEMIKE 267 Query: 207 NPH 209 H Sbjct: 268 GKH 270 >5JE5-A nrPDB Length = 247 Score = 51.7 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 31/114 (27%), Positives = 40/114 (35%), Gaps = 4/114 (3%) Query: 63 SSLPLGRALVPGCGGGHDVVAMASPERF-VVGLDISESALAKANETYGSSPKAEYFSFVK 121 + L CG G + VVG+DISE + A E S + F Sbjct: 38 GDVSGKSVLDLACGFGFFGREIYRRGAAKVVGVDISEKMIELARE--ESRKYGDPLEFHV 95 Query: 122 EDVFTWRPTELFDLIFDYVFF-CAIEPEMRPAWAKSMYELLKPDGELITLMYPI 174 DV P FDL+ F A E K + LKPDG+L+ Sbjct: 96 RDVANMEPLGQFDLVNAAWLFNYADSVENLRKMFKVVRASLKPDGKLVAYTVDP 149 >5U19-A nrPDB Length = 341 Score = 51.7 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 31/168 (18%), Positives = 64/168 (38%), Gaps = 19/168 (11%) Query: 67 LGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFT 126 RAL GCG G + +A V+G+D++ A+A + + +F + D+F Sbjct: 144 GARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALSRLNAALNGLT-NVTFREGDMFE 202 Query: 127 WRPTELFDLIFDYV-------FFCAIEPEM--RPAWAKSMYELLKPDGELITLMYPITDH 177 ++F+ F +E + +++ L+ G ++ + + D+ Sbjct: 203 PAEGRFSRIVFNSPTNEEGNEFVDLLEAGEPILETFFRNVPRKLESGG-IVEVNLAMNDY 261 Query: 178 VGGPPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKGKEKLGRWKK 225 G P++ E + +G + R+ E G WK+ Sbjct: 262 -PGDPFR------ERLADWLGLTENGLRVQIFT-SQRRATESGGEWKR 301 >3E23-A nrPDB Length = 211 Score = 50.1 bits (118), Expect = 7e-07, Method: Composition-based stats. Identities = 21/126 (16%), Positives = 41/126 (32%), Gaps = 7/126 (5%) Query: 40 WEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISES 99 + T + + + + + L GCG G+ AM + V D S Sbjct: 17 YRGNATAYAERQPRSATLTKFLGELPAGAKILELGCGAGYQAEAMLAAGFDVDATDGSPE 76 Query: 100 ALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYE 159 A+A+ G + F + +D ++ + + + K ++ Sbjct: 77 LAAEASRRLGRPVRTMLFH-------QLDAIDAYDAVWAHACLLHVPRDELADVLKLIWR 129 Query: 160 LLKPDG 165 LKP G Sbjct: 130 ALKPGG 135 >4X3Q-A nrPDB Length = 355 Score = 50.1 bits (118), Expect = 8e-07, Method: Composition-based stats. Identities = 35/151 (23%), Positives = 56/151 (37%), Gaps = 6/151 (3%) Query: 35 GWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMAS--PERFVV 92 G E+ + + W Q + P+++ D + + R L G G + VA+A P V Sbjct: 142 GLEELFYRGMHAWSQ-LSNPVLLAQPDFT--RVHRVLDVGGGDAVNAVALARAHPSLRVT 198 Query: 93 GLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPA 152 LD AL A +T + E D+FT D + PE Sbjct: 199 VLD-RPGALEVARKTIAEAGLEERVRTHAADIFTDSYPAGHDCVLFAHQLVIWSPEQNLT 257 Query: 153 WAKSMYELLKPDGELITLMYPITDHVGGPPY 183 + Y+ ++P G ++ D GP Y Sbjct: 258 LLRKAYDAVEPGGRVLVFNAFTDDDRTGPLY 288 >2XVM-A nrPDB Length = 199 Score = 50.1 bits (118), Expect = 8e-07, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 51/147 (34%), Gaps = 8/147 (5%) Query: 65 LPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALA-KANETYGSSPKAEYFSFVKED 123 + G+ L GCG G + + +A+ V D + ++A + + V + Sbjct: 31 VKPGKTLDLGCGNGRNSLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNLHTRVVDLN 90 Query: 124 VFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDG-ELITLMYPITDH--VGG 180 T+ +D I V +E + P +M KP G LI D+ G Sbjct: 91 NLTFDR--QYDFILSTVVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDTADYPCTVG 148 Query: 181 PPYKVDVSTFEEVLVPIGFKAVSVEEN 207 P+ G++ V E+ Sbjct: 149 FPFAFKEGELRRYYE--GWERVKYNED 173 >4KRI-A nrPDB Length = 433 Score = 48.6 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 43/195 (22%), Positives = 69/195 (35%), Gaps = 18/195 (9%) Query: 26 FLHKT--VEEGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLG-RALVPGCGGGHDVV 82 FL +T + G + W G + L + G R L G G G Sbjct: 179 FLDRTQYTDTGIFAYEWIFGNNFISPGGWNQNLAILKRFGPMKTGQRMLDIGVGIGGGAR 238 Query: 83 AMASP-ERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR-PTELFDLIFDYV 140 AS V G+D+S + LA A E ++ D + FD +F Sbjct: 239 QAASEFGLQVHGVDLSTNMLAVALERVHKEKD-ARVTYAVCDACEYEFEPNSFDYVFSRD 297 Query: 141 FFCAIEPEMRPAWAKSMYELLKPDGELITLMYPI---------TDHVGGPPYKV-DVSTF 190 I+ + +Y LKP G+++ MY + ++V Y + ++ Sbjct: 298 CIQHIKDTDKLF--SRIYRALKPGGKVLITMYGVGHGTLSESFKEYVSQRQYYLKNLEQI 355 Query: 191 EEVLVPIGFKAVSVE 205 EE+ GF + VE Sbjct: 356 EEIAKKTGFIDIEVE 370 >5MGZ-A nrPDB Length = 236 Score = 48.2 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 29/122 (23%), Positives = 47/122 (38%), Gaps = 7/122 (5%) Query: 56 IVHLVDTSSLPLGR-ALVPGCGGGHDVVAMAS--PERFVVGLDISESALAKANETYGSSP 112 V L+ + + G+ + CG G V ++S P +VG+D+SE + A E Sbjct: 28 FVDLLVGAGIADGQTVVDLCCGSGELEVILSSRFPSLNLVGVDLSEDMVRIAREYAAEQG 87 Query: 113 KAEYFSFVKEDVFT--WRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITL 170 KA F + DL+ F + PA +M L KP G ++ Sbjct: 88 KALEFRHGDAQLLAGMEDLAGKADLVVSRNAFHRLT--RLPAAFDTMLRLAKPGGAVLNC 145 Query: 171 MY 172 + Sbjct: 146 SF 147 >4HGY-A nrPDB Length = 276 Score = 47.1 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 37/108 (34%), Gaps = 3/108 (2%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRP 129 L G G G +A V G++ SE L K E + P V + Sbjct: 66 VLELGVGTGRVAFPLADLGVEVHGVESSEPMLDKLREKAAAHPNGNLVVPVLGNFAKLDL 125 Query: 130 TE-LFDLIFDY--VFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPI 174 E + ++F FC + + + + ELL+P G + Sbjct: 126 GEQRYSVVFAAFNTLFCLLGQDEQIDCMRQARELLEPGGTFVVQCLNP 173 >5EVJ-A nrPDB Length = 387 Score = 47.1 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 46/117 (39%), Gaps = 13/117 (11%) Query: 63 SSLPLGRALVPGCGGGHD---VVAMASPERFVVGLDISESALAKANETYGSSPK------ 113 + + R L G G G D + + V G+D++ + L A + + Sbjct: 80 AGIEGLRVLDLGAGSGRDAYVAAKLVGEKGSVTGVDMTPAQLEVAISHADAYARDKLGYG 139 Query: 114 AEYFSFVKEDVFTWRPTELFDLIFDYVFF-CAIE--PEMRPAWAKSMYELLKPDGEL 167 +F++ ++ L D FD V C I P+ +++ Y +L P GE+ Sbjct: 140 KSNMTFIQGEIEYLDRAGLEDSSFDLVISNCVINLSPDKARVLSEA-YRVLAPGGEM 195 >4AZW-A nrPDB Length = 471 Score = 47.1 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 52/159 (32%), Gaps = 11/159 (6%) Query: 60 VDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAE---Y 116 + + L GC G +++AS +VG+D + + +P Sbjct: 60 LSRALGRPLNVLDLGCAQGFFSLSLASKGATIVGIDFQQENINVCRALAEENPDFAAEFR 119 Query: 117 FSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITD 176 ++E + E FDL F I K + L + + L + + Sbjct: 120 VGRIEEVIAALEEGE-FDLAIGLSVFHHIVHLHGIDEVKRLLSRLADVTQAVILELAVKE 178 Query: 177 HVGGPPYKVDVSTFE---EVLVPIGFKAVSVEENPHAIP 212 P+ VS + E++ F + E + H P Sbjct: 179 E----PFYWGVSQPDDPRELIEQCAFYRLIGEFDTHLSP 213 >4AZV-A nrPDB Length = 569 Score = 47.1 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 52/159 (32%), Gaps = 11/159 (6%) Query: 60 VDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAE---Y 116 + + L GC G +++AS +VG+D + + +P Sbjct: 60 LSRALGRPLNVLDLGCAQGFFSLSLASKGATIVGIDFQQENINVCRALAEENPDFAAEFR 119 Query: 117 FSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITD 176 ++E + E FDL F I K + L + + L + + Sbjct: 120 VGRIEEVIAALEEGE-FDLAIGLSVFHHIVHLHGIDEVKRLLSRLADVTQAVILELAVKE 178 Query: 177 HVGGPPYKVDVSTFE---EVLVPIGFKAVSVEENPHAIP 212 P+ VS + E++ F + E + H P Sbjct: 179 E----PFYWGVSQPDDPRELIEQCAFYRLIGEFDTHLSP 213 >4KDR-A nrPDB Length = 223 Score = 47.1 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 35/151 (23%), Positives = 58/151 (38%), Gaps = 12/151 (7%) Query: 21 EEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHD 80 EE+A F + V W+ E E P + L L + L GCGGG Sbjct: 21 EEIAKF--EAVASRWWD--LEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGIL 76 Query: 81 VVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFT--WRPTELFDLIF- 137 +MA V GLD+ L A S +V+E V + +D++ Sbjct: 77 AESMAREGATVTGLDMGFEPLQVAKLHALESGI--QVDYVQETVEEHAAKHAGQYDVVTC 134 Query: 138 DYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 + +P+ + ++ +L+KP G++ Sbjct: 135 MEMLEHVPDPQ---SVVRACAQLVKPGGDVF 162 >4KDC-A nrPDB Length = 246 Score = 47.1 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 35/151 (23%), Positives = 58/151 (38%), Gaps = 12/151 (7%) Query: 21 EEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHD 80 EE+A F + V W+ E E P + L L + L GCGGG Sbjct: 21 EEIAKF--EAVASRWWD--LEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGIL 76 Query: 81 VVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFT--WRPTELFDLIF- 137 +MA V GLD+ L A S +V+E V + +D++ Sbjct: 77 AESMAREGATVTGLDMGFEPLQVAKLHALESGI--QVDYVQETVEEHAAKHAGQYDVVTC 134 Query: 138 DYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 + +P+ + ++ +L+KP G++ Sbjct: 135 MEMLEHVPDPQ---SVVRACAQLVKPGGDVF 162 >1RI1-A nrPDB Length = 298 Score = 46.3 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 39/109 (35%), Gaps = 5/109 (4%) Query: 66 PLGRALVPGCGGGHDVVAMASPE-RFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 L GCG G D++ G+DI+E ++ A + + F +D Sbjct: 64 RGDSVLDLGCGKGGDLLKYERAGIGEYYGVDIAEVSINDARVRARNMKRRFKVFFRAQDS 123 Query: 125 FT--WRPTELFDLIFDYVFFC-AIEPEMRPAWA-KSMYELLKPDGELIT 169 + + FD+I F A A +++ L+P G I Sbjct: 124 YGRHMDLGKEFDVISSQFSFHYAFSTSESLDIAQRNIARHLRPGGYFIM 172 >2GLU-A nrPDB Length = 239 Score = 46.3 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 42/112 (37%), Gaps = 5/112 (4%) Query: 69 RALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 R L G G GH +A + + +G+D ++ + A+ E F + + Sbjct: 24 RVLDIGAGAGHTALAFSPYVQECIGVDATKEMVEVASSFAQEKGV-ENVRFQQGTAESLP 82 Query: 129 -PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITL-MYPITDHV 178 P + FD+I + + + +LK DG + + Y D V Sbjct: 83 FPDDSFDIITCRYAAHHFSDVRKA--VREVARVLKQDGRFLLVDHYAPEDPV 132 >5F8E-A nrPDB Length = 377 Score = 46.3 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 7/107 (6%) Query: 67 LGRALVPGCGGGHDVVAMASP--ERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 GCG G V MA G+D S+ A+A E +F + D+ Sbjct: 188 GADVADFGCGSGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGL-ANATFERHDL 246 Query: 125 FTWRPTELFDLIFDYVFFCAIEPEMRPAWA-KSMYELLKPDGELITL 170 +D+I F AI + +PA +++Y L+P G L+ + Sbjct: 247 AELDKVGAYDVI---TVFDAIHDQAQPARVLQNIYRALRPGGVLLMV 290 >1L3B-A nrPDB Length = 192 Score = 46.3 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 33/101 (32%), Gaps = 6/101 (5%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFT-WR 128 A+ GCG G + +A R V +D + A++ + + ++ D Sbjct: 37 AVDVGCGTGGVTLELAGRVRRVYAIDRNPEAISTTEMNLQRHGLGDNVTLMEGDAPEALC 96 Query: 129 PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 D+ + + + LKP G +I Sbjct: 97 KIPDIDIAVVGG-----SGGELQEILRIIKDKLKPGGRIIV 132 >1VL5-A nrPDB Length = 260 Score = 46.3 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 44/117 (37%), Gaps = 5/117 (4%) Query: 56 IVHLVDTSSLPLGR-ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKA 114 + L+ ++L L GGGH A A + VV D++E L A + Sbjct: 26 LAKLMQIAALKGNEEVLDVATGGGHVANAFAPFVKKVVAFDLTEDILKVARAFIEGNG-H 84 Query: 115 EYFSFVKEDVFTWRPT-ELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITL 170 + +V+ D T E F ++ + + Y +LK G+L+ + Sbjct: 85 QQVEYVQGDAEQMPFTDERFHIVTCRIAAHHFPNPAS--FVSEAYRVLKKGGQLLLV 139 >3SVZ-A nrPDB Length = 263 Score = 45.9 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 34/95 (35%), Gaps = 3/95 (3%) Query: 68 GRALVPGCGGGHDVVAMASPER-FVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFT 126 + GCG G + +A + + G+D+ + NE + A+ + + Sbjct: 54 AKIADIGCGTGGQTLFLADYVKGQITGIDLFPDFIEIFNENAVKANCADRVKGITGSMDN 113 Query: 127 WR-PTELFDLIFDYVFFCAIEPEM-RPAWAKSMYE 159 E DLI+ I E W+K + + Sbjct: 114 LPFQNEELDLIWSEGAIYNIGFERGMNEWSKYLKK 148 >4GEK-A nrPDB Length = 261 Score = 45.9 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 23/148 (15%), Positives = 49/148 (33%), Gaps = 13/148 (8%) Query: 34 GGWE-KCWEEEITPWDQGRATPLIVHLVDTSSL-------PLGRALVPGCGGGHDVVAMA 85 G W E+ P R+ P +++ + P + GC G +++ Sbjct: 30 GDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVR 89 Query: 86 SP----ERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVF 141 ++ +D S + + + + ++ D+ E ++ Sbjct: 90 RNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIA-IENASMVVLNFT 148 Query: 142 FCAIEPEMRPAWAKSMYELLKPDGELIT 169 +EP R A +Y+ L P G L+ Sbjct: 149 LQFLEPSERQALLDKIYQGLNPGGALVL 176 >5M58-A nrPDB Length = 230 Score = 45.9 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 28/124 (22%), Positives = 49/124 (39%), Gaps = 11/124 (8%) Query: 56 IVHLVDTSSLPLGR-ALVPGCGGGHDVVAMAS--PERFVVGLDISESALAKANETYGSSP 112 V L+ + + G+ + CG G + + S P +VG+D+SE + A + Sbjct: 28 FVDLLVGAGIADGQTVVDLCCGSGELEIILTSRFPSLNLVGVDLSEDMVRIARDYAAEQG 87 Query: 113 KAEYFSFVKEDVFTWRPTELF----DLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 K F D + E DL+ F + PA +M L+KP G ++ Sbjct: 88 K--ELEFRHGDAQSPAGMEDLLGKADLVVSRHAFHRLT--RLPAGFDTMLRLVKPGGAIL 143 Query: 169 TLMY 172 + + Sbjct: 144 NVSF 147 >2AS0-A nrPDB Length = 396 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 52/148 (35%), Gaps = 20/148 (13%) Query: 66 PLGRALVPGCGGGHDVVAMASPERF-VVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 P R L G + A V+G+D S A+ A E + + F+ Sbjct: 217 PGDRVLDVFTYTGGFAIHAAIAGADEVIGIDKSPRAIETAKENAKLNGVEDRMKFIVGSA 276 Query: 125 FT-----WRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYEL------LKPDGELITLMYP 173 F + E FD++ + A ++ + + L DG ++ Sbjct: 277 FEEMEKLQKKGEKFDIVVLDPPAFVQHEKDLKAGLRAYFNVNFAGLNLVKDGGILVTC-S 335 Query: 174 ITDHVGGPPYKVDVSTFEEVLVPIGFKA 201 + H VD+ F+++++ G KA Sbjct: 336 CSQH-------VDLQMFKDMIIAAGAKA 356 >3HNR-A nrPDB Length = 220 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 37/110 (33%), Gaps = 5/110 (4%) Query: 59 LVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFS 118 L D + G L G G G+ + R V G++ S A E FS Sbjct: 38 LEDVVNKSFGNVLEFGVGTGNLTNKLLLAGRTVYGIEPSREMRMIAKEKLPKE-----FS 92 Query: 119 FVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 + D ++ D I F + + + +LL G+++ Sbjct: 93 ITEGDFLSFEVPTSIDTIVSTYAFHHLTDDEKNVAIAKYSQLLNKGGKIV 142 >6CU3-A nrPDB Length = 336 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 39/106 (36%), Gaps = 9/106 (8%) Query: 70 ALVPGCGGGHDVVAMASPE-RFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 L GCG G + A + V+G+D+S+ + KA + + + +K V Sbjct: 55 VLDIGCGTGILCLFAAKAGAKRVIGIDMSDI-IDKARQIVSDNGYSHVIELIKGKVEDIA 113 Query: 129 PT----ELFDLIFDY--VFFCAIEPEMRPAWAKSMYELLKPDGELI 168 E D+I +F E M + L+P G L Sbjct: 114 QLPFGIEKVDIIISEWMGYFLLYES-MLQTVLSARDRWLRPGGYLF 158 >4QDJ-A nrPDB Length = 238 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 38/174 (21%), Positives = 61/174 (35%), Gaps = 32/174 (18%) Query: 48 DQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANET 107 Q ++ LV +LP GCG G + +A V G DISE + +A + Sbjct: 44 HQQTVDSVVAWLVADGNLPGLLVCDAGCGVGSLSIPLAQAGALVYGSDISEKMVGEAQQK 103 Query: 108 ------YGSSPK----------AEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRP 151 YG+ P +Y + + DV PTE + ++ A + Sbjct: 104 AQEVLAYGNQPTFMTQDLAQLGGKYDTVICLDVLIHYPTEEASAMISHLASLADRRLILS 163 Query: 152 AWAKSM-YELLKPDGELITLMYPITDHVGGP-----PYKVDVSTFEEVLVPIGF 199 K++ +LK G L GP Y+ + ++L GF Sbjct: 164 FAPKTLGLTVLKKIGGLF----------PGPSKTTRAYQHKEADIRKILGDNGF 207 >1WXW-A nrPDB Length = 382 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 31/136 (22%), Positives = 50/136 (36%), Gaps = 15/136 (11%) Query: 66 PLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVF 125 RAL G + +A R VV +D S AL +A E + ++ + F Sbjct: 209 RGERALDVFSYAGGFALHLALGFREVVAVDSSAEALRRAEENARLNGLG-NVRVLEANAF 267 Query: 126 TW-----RPTELFDLIF-DYVFFCAIEPEMRPAWAK------SMYELLKPDGELITLMYP 173 + E FDL+ D F + ++ A+ +LLK G L T Sbjct: 268 DLLRRLEKEGERFDLVVLDPPAFAKGKKDVERAYRAYKEVNLRAIKLLKEGGILATAS-- 325 Query: 174 ITDHVGGPPYKVDVST 189 + H+ P + V+ Sbjct: 326 CSHHMTEPLFYAMVAE 341 >1D2C-A nrPDB Length = 292 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 41/114 (35%), Gaps = 13/114 (11%) Query: 69 RALVPGCGGGHDVVAMASPERFVVGLDISESALAKA-NETYGSSPKAEYFSFV--KEDVF 125 R L CG G D + + V +D S+ L A E + + + +V + + Sbjct: 59 RVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWL 118 Query: 126 TW----RPTELFDLIFDYVFFCAIEPE------MRPAWAKSMYELLKPDGELIT 169 T + FD + A P+ K++ +++P G L+ Sbjct: 119 TLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVI 172 >4ISC-A nrPDB Length = 164 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 42/123 (34%), Gaps = 10/123 (8%) Query: 57 VHLVDTSSLPLGR---ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPK 113 + ++LP R PGC G +A +V D S A+ A + P Sbjct: 7 KRALTLAALPRERYRAIFEPGCANGELSADLAERCDMLVCCDTSTQAVELARQRLADVP- 65 Query: 114 AEYFSFVKEDVFTWRPTELFDLIF--DYVFFCAIEPEMRPAWAKSMYELLKPDGELITLM 171 + V+ + P FDLI + ++ R L PDG+L+ Sbjct: 66 --HARVVQARLPHQWPAGQFDLIVFSELGYYLDAADLHRL--IDCALAALSPDGQLLACH 121 Query: 172 YPI 174 + Sbjct: 122 WRP 124 >4IWN-A nrPDB Length = 229 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 21/143 (14%), Positives = 47/143 (32%), Gaps = 12/143 (8%) Query: 38 KCWEEEITPWDQGRATPLIVHLVDTSSL-------PLGRALVPGCGGGHDVVAMASP--- 87 E+ P R+ P +++ + P + GC G +++ Sbjct: 3 DERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHH 62 Query: 88 -ERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIE 146 ++ +D S + + + + ++ D+ E ++ +E Sbjct: 63 DNCKIIAIDNSPAMIERCRHHIDAYKAPTPVDVIEGDIRDIA-IENASMVVLNFTLQFLE 121 Query: 147 PEMRPAWAKSMYELLKPDGELIT 169 P R A +Y+ L P G L+ Sbjct: 122 PSERQALLDKIYQGLNPGGALVL 144 >5BSZ-A nrPDB Length = 250 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 41/108 (37%), Gaps = 11/108 (10%) Query: 66 PLGR-ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 P R L CG G + + G+++S + A A ++P + D+ Sbjct: 46 PGARSLLDVACGTGEHLAHLVEHFPDAAGVELSPAMRAAAERKLTATPVH------QADM 99 Query: 125 FTWRPTELFDLI---FDYVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 F + +FD + + + A E+ A ++M L G L+ Sbjct: 100 FDFDLGRVFDAVCCLTGSIAYAADTAELARA-VRAMARHLPVGGVLVI 146 >4INE-A nrPDB Length = 454 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 5/109 (4%) Query: 66 PLGRALVPGCGGGHDVVAMASP-ERFVVGLDISESALAKANETYGSSPKA-EYFSFVKED 123 P L G G G +A V G+D+S + LA A E + +S Sbjct: 241 PGQTMLDIGVGIGGGARQVADEFGVHVHGIDLSSNMLAIALERLHEEKDSRVKYSITDAL 300 Query: 124 VFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMY 172 V+ + FD +F I P+ +++ +Y+ LKP G+++ MY Sbjct: 301 VYQFED-NSFDYVFSRDCIQHI-PDTEKLFSR-IYKALKPGGKVLITMY 346 >3TM5-A nrPDB Length = 373 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 21/142 (14%), Positives = 53/142 (37%), Gaps = 11/142 (7%) Query: 37 EKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPER--FVVGL 94 ++ W P + + +++ + L G L P CG G ++ +A ++G+ Sbjct: 190 KRPWRVYDHPAHLKAS--IANAMIELAELDGGSVLDPMCGSGTILIELALRRYSGEIIGI 247 Query: 95 DISESALAKANETYGSSPKAEYFSFVKEDVFTWRPT-ELFDLIFDYVFF------CAIEP 147 + L A ++ + F++ D + D + + ++ P Sbjct: 248 EKYRKHLIGAEMNALAAGVLDKIKFIQGDATQLSQYVDSVDFAISNLPYGLKIGKKSMIP 307 Query: 148 EMRPAWAKSMYELLKPDGELIT 169 ++ + + ++L+ G IT Sbjct: 308 DLYMKFFNELAKVLEKRGVFIT 329 >4FS8-A nrPDB Length = 383 Score = 44.4 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 37/187 (19%), Positives = 63/187 (33%), Gaps = 32/187 (17%) Query: 12 NGGNVIPTPEEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLVDT--------- 62 NGG+ + VA + KT++ K ++ ++ + D Sbjct: 14 NGGSTPSIRDHVADYYGKTLQSSADLKTSACKLAAAVPESHRKILADIADEVLEKFYGCG 73 Query: 63 ------SSLPLGRALVPGCGGGHD---VVAMASPERFVVGLDISESALAKAN-------E 106 SL L GCG G D + V+G+D+ ++ L A E Sbjct: 74 STLPADGSLEGATVLDLGCGTGRDVYLASKLVGEHGKVIGVDMLDNQLEVARKYVEYHAE 133 Query: 107 TYGSSPKAEYFSFVKEDVFTWRPTE---LFDLIFDYVF---FCAIEPEMRPAWAKSMYEL 160 + SP F+K + E + D D V C + + K ++ + Sbjct: 134 KFFGSPSRSNVRFLKGFIENLATAEPEGVPDSSVDIVISNCVCNLSTNKLALF-KEIHRV 192 Query: 161 LKPDGEL 167 L+ GEL Sbjct: 193 LRDGGEL 199 >5BXY-A nrPDB Length = 158 Score = 44.0 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 52/130 (40%), Gaps = 8/130 (6%) Query: 52 ATPLIVHLVDTSSLPLGRAL-VPGCGGGHDVVAMA-SPERFVVGLDISESALAKANETYG 109 P++ +++ + + L G G G V+ A + VG++I + KA + Sbjct: 9 PKPVVDRMLELADVDETDVLYDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAK 68 Query: 110 SSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 + A+ F + D+F +E + ++ ++RP ++E L P +++ Sbjct: 69 EAGVADLVEFRQGDLFEADISEA--TVVTLYLLPSVNQKLRPI----LFEQLSPGTPVVS 122 Query: 170 LMYPITDHVG 179 + + Sbjct: 123 HDFDMGRWAP 132 >2PJD-A nrPDB Length = 343 Score = 44.0 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 38/157 (24%), Positives = 56/157 (35%), Gaps = 18/157 (11%) Query: 68 GRALVPGCGGGHDVVAMA--SPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVF 125 G+ L GCG G VA A SP+ + D+S A+ + T ++ +VF Sbjct: 198 GKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANGVEG--EVFASNVF 255 Query: 126 TWRPTELFDLIFDYVFFCAIEPEMRPA---WAKSMYELLKPDGELITLMYPITDHVGGPP 182 + FD+I F A + L GEL + + P Sbjct: 256 S-EVKGRFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVA---NAFLPYPD 311 Query: 183 YKVDVSTFEEVLVPIG-FKAVSVEENPHAIPTRKGKE 218 + F EV+ G FK AI TR+ K+ Sbjct: 312 VLDETFGFHEVIAQTGRFKVY------RAIMTRQAKK 342 >1Y8C-A nrPDB Length = 246 Score = 43.6 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 41/110 (37%), Gaps = 9/110 (8%) Query: 71 LVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPT 130 L CG G+ + + +D+S+ L++A + S +D+ Sbjct: 42 LDLACGTGNLTENLCPKFKNTWAVDLSQEMLSEAENKFRSQGL--KPRLACQDISNLNIN 99 Query: 131 ELFDLI---FDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDH 177 FDLI D + I+ + + K++ LK G ++ I + Sbjct: 100 RKFDLITCCLDSTNY-IIDSDDLKKYFKAVSNHLKEGG---VFIFDINSY 145 >1P91-A nrPDB Length = 269 Score = 43.6 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 33/140 (23%), Positives = 48/140 (34%), Gaps = 27/140 (19%) Query: 48 DQGRATPL----IVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVV--GLDISESAL 101 D G PL + L + L GCG G+ A A + GLD+S+ A+ Sbjct: 63 DAGHYQPLRDAIVAQLRERLDDKATAVLDIGCGEGYYTHAFADALPEITTFGLDVSKVAI 122 Query: 102 AKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELL 161 A + Y +F + D D AI P A+ + ++ Sbjct: 123 KAAAKRYPQ------VTFCVASSHRLPFS---DTSMD-----AIIRIYAPCKAEELARVV 168 Query: 162 KPDGELITLMYPITDHVGGP 181 KP G +IT GP Sbjct: 169 KPGGWVITAT-------PGP 181 >4IV8-A nrPDB Length = 284 Score = 43.2 bits (100), Expect = 9e-05, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 40/109 (36%), Gaps = 5/109 (4%) Query: 66 PLGRALVPGCGGGHDVVAM-ASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 P + L G G G + + V G+DI E +A A + F D+ Sbjct: 72 PNSKVLDIGSGLGGGCKYINEKYDAHVYGVDICEKMIAIAKL---RNKDKSKVEFEAMDI 128 Query: 125 FTWRPTE-LFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMY 172 E FD+I+ + + + Y+ LKP+G L+ Y Sbjct: 129 LKKDFPECTFDMIYSRDAILHLPYADKKKLFEKCYKWLKPNGILLITDY 177 >6BQC-A nrPDB Length = 383 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 29/129 (22%), Positives = 48/129 (37%), Gaps = 12/129 (9%) Query: 40 WEEEITPWDQGRATPL-IVHLVDTSSLPLG-RALVPGCGGGHDVVAMASP-ERFVVGLDI 96 W++ A + + + L G R L GCG G MAS + VVG+ I Sbjct: 143 WKDADN---LESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTI 199 Query: 97 SESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKS 156 S A+ + + + + +D + FD I F + P+ + Sbjct: 200 S----AEQQKMAQERCEGLDVTILLQDYRDLN--DQFDRIVSVGMFEHVGPKNYDTYFAV 253 Query: 157 MYELLKPDG 165 + LKP+G Sbjct: 254 VDRNLKPEG 262 >3DMF-A nrPDB Length = 381 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 25/167 (14%), Positives = 52/167 (31%), Gaps = 15/167 (8%) Query: 54 PLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPK 113 + + + + L G G G + +A VVG++ +++ + ++ Sbjct: 221 EALQERLGPEGVRGRQVLDLGAGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANAL 280 Query: 114 AEYFSFVKEDVFTWRPTELFDLIFDYVFFC---AIEPEMRPAWAKSMYELLKPDGELITL 170 D FD+I F A+ ++ A+ L+P G + Sbjct: 281 KAQALHSDVD-EALTEEARFDIIVTNPPFHVGGAVILDVAQAFVNVAAARLRPGGVFFLV 339 Query: 171 MYPITDHVGGPPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKGK 217 P + EE F+ + V E ++G+ Sbjct: 340 SNPFLKYEP---------LLEEKFG--AFQTLKVAEYKVLFAEKRGR 375 >4MWZ-A nrPDB Length = 267 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 38/107 (35%), Gaps = 5/107 (4%) Query: 68 GRALVPGCGGGHDVVAM-ASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFT 126 + L G G G + V G+DI E + A + F +D+ Sbjct: 57 SKVLDIGSGLGGGCKYINEKYGAHVHGVDICEKMVTIAKL---RNQDKAKIEFEAKDILK 113 Query: 127 WR-PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMY 172 P FD+I+ + + + Y+ LKP+G L+ Y Sbjct: 114 KDFPESTFDMIYSRDSILHLSYADKKMLFEKCYKWLKPNGILLITDY 160 >4DZR-A nrPDB Length = 215 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 22/65 (33%), Gaps = 4/65 (6%) Query: 65 LPLGRALVPGCGGG--HDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKE 122 R + G G G +A+A P V +D+S ALA A + Sbjct: 29 PSGTRVIDVGTGSGCIAVSIALACPGVSVTAVDLSMDALAVARRNAERFG--AVVDWAAA 86 Query: 123 DVFTW 127 D W Sbjct: 87 DGIEW 91 >1TPY-A nrPDB Length = 287 Score = 41.7 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 50/134 (37%), Gaps = 9/134 (6%) Query: 40 WEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDV-VAMASPERFVVGLDISE 98 +E E ++ + + + L P L GCG G + A+A + VVGL +S+ Sbjct: 38 FEREDMTLEEAQIAKIDLALGKLGLQPGMTLLDIGCGWGATMRRAIAQYDVNVVGLTLSK 97 Query: 99 SALAKANETYGS--SPKAEYFSFVKEDVFTWRPTEL-FDLIFDYVFFCAIEPEMRPAWAK 155 + A +++ +P+ W D I F + + Sbjct: 98 NQAAHVQKSFDEMDTPRDRRVLLA-----GWEQFNEPVDRIVSIGAFEHFGHDRHADFFA 152 Query: 156 SMYELLKPDGELIT 169 +++L PDG L+ Sbjct: 153 RAHKILPPDGVLLL 166 >4KIC-A nrPDB Length = 357 Score = 41.7 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 48/150 (32%), Gaps = 9/150 (6%) Query: 54 PLIVHLVDTSSLPLGRALVPGCGGGHDVVAMAS--PERFVVGLDISESALAKANETYGSS 111 P VD G G G ++ +A P +G+DI++ A+A A + + Sbjct: 166 PAFWAAVDGLGYTPTTVADLGSGSGERLIQIARRFPGVRGLGVDIADGAIAMAEKEVAAK 225 Query: 112 PKAEYFSFVKEDVFTWRP------TELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDG 165 + SFV+ D T DL+ ++ P P+ Sbjct: 226 GFGDQISFVRGDARTIDQVSARGEFAEVDLLTCFMMGHDFWPRENCVQTLRKLRAAFPNV 285 Query: 166 ELITLMYPITDHVGGPPYKVDVSTFEEVLV 195 L T VG P ++ V T Sbjct: 286 RRFLLG-DATRTVGIPDRELPVFTLGFEFG 314 >3GU3-A nrPDB Length = 284 Score = 41.3 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 40/111 (36%), Gaps = 9/111 (8%) Query: 67 LGRALVPGCGGGHDVVAMASP---ERFVVGLDISESALAKANETYGSSPKAEYFSFVKED 123 + GCG G+ + + G+D E+ LA+A E + P F++ D Sbjct: 23 PVHIVDYGCGYGYLGLVLMPLLPEGSKYTGIDSGETLLAEARELFRLLPYDS--EFLEGD 80 Query: 124 VFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPI 174 + +D+ + F + + M +K G++ + + Sbjct: 81 ATEIELNDKYDIAICHAFLLHMTTPETML--QKMIHSVKKGGKI--ICFEP 127 >3I9F-A nrPDB Length = 170 Score = 40.5 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 51/142 (35%), Gaps = 17/142 (11%) Query: 50 GRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYG 109 R + ++ + G + GCG G + + +DI+ AL + E + Sbjct: 4 ERPEEYLPNIFE---GKKGVIVDYGCGNGFYCKYLLEFATKLYCIDINVIALKEVKEKFD 60 Query: 110 SSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEM--RPAWAKSMYELLKPDGEL 167 S + P E+ D D++ F +M + + +LK DG + Sbjct: 61 SV------------ITLSDPKEIPDNSVDFILFANSFHDMDDKQHVISEVKRILKDDGRV 108 Query: 168 ITLMYPITDHVGGPPYKVDVST 189 I + + + GPP + + Sbjct: 109 IIIDWRKENTGIGPPLSIRMDE 130 >1NKV-A nrPDB Length = 256 Score = 40.5 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 53/163 (32%), Gaps = 22/163 (13%) Query: 45 TPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDV-VAMASPERFVVGLDISESALAK 103 P+ + + L L P R L G G G + G+D+S A+ Sbjct: 18 NPFTEEKYATLGRVLRMK---PGTRILDLGSGSGEMLCTWARDHGITGTGIDMSSLFTAQ 74 Query: 104 ANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKS---MYEL 160 A +E F+ D + E D V C + +A + + + Sbjct: 75 AKRRAEELGVSERVHFIHNDAAGYVANEKCD-----VAACVGATWIAGGFAGAEELLAQS 129 Query: 161 LKPDGELITLMYPITDHVGGPPYKVDVSTFEEVLVPIGFKAVS 203 LKP G ++ G PY + EE+ G + S Sbjct: 130 LKPGGIMLI----------GEPYWRQLPATEEIAQACGVSSTS 162 >3CJR-A nrPDB Length = 254 Score = 40.1 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 43/137 (31%), Gaps = 17/137 (12%) Query: 40 WEEEITPWDQGRATPLIVHLVDTSSL----------PLGRALVPGCGGGHDVVAMASPER 89 WE P +T+ L P + L G G G +A Sbjct: 84 WEGAEIPLVIEPGMAFGTGHHETTRLALKALARHLRPGDKVLDLGTGSGVLAIAAEKLGG 143 Query: 90 FVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEM 149 +G+DI L +A + F++ + P FDL+ ++ E+ Sbjct: 144 KALGVDIDPMVLPQAEANAKRNGVRP--RFLEGSLEAALPFGPFDLLVANLYA-----EL 196 Query: 150 RPAWAKSMYELLKPDGE 166 A A E L P G Sbjct: 197 HAALAPRYREALVPGGR 213 >4FGZ-A nrPDB Length = 266 Score = 39.4 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 5/111 (4%) Query: 68 GRALVPGCGGGHDVVAM-ASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFT 126 + L G G G + + G+DI + + ANE + K F D+ T Sbjct: 57 SKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNNK---IIFEANDILT 113 Query: 127 WR-PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITD 176 P FDLI+ + E + + Y+ LKP G L+ Y T+ Sbjct: 114 KEFPENNFDLIYSRDAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATE 164 >2B3T-A nrPDB Length = 276 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 30/73 (41%), Gaps = 3/73 (4%) Query: 67 LGRALVPGCGGGHDVVAMAS--PERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 R L G G G +A+AS P+ ++ +D A++ A + ++ D Sbjct: 110 PCRILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAI-KNIHILQSDW 168 Query: 125 FTWRPTELFDLIF 137 F+ + F +I Sbjct: 169 FSALAGQQFAMIV 181 >1R74-A nrPDB Length = 294 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 42/117 (35%), Gaps = 17/117 (14%) Query: 69 RALVPGCGGGHDVVAMASPERFVVGLDISESALAKA-NETYGSSPKAEYFSFVKEDVFTW 127 R L CG G D + + V +D S+ L A E + + + +V E+ W Sbjct: 59 RVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEA-NW 117 Query: 128 RPTEL---------FDLI------FDYVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 + FD + F ++ C + K++ +++ G L+ Sbjct: 118 MTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVI 174 >5BP7-A nrPDB Length = 271 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 40/129 (31%), Gaps = 13/129 (10%) Query: 66 PLGRALVPGCGGGHDV-VAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 P R L G G G + G+D+S+ A+A A+ +F+ D Sbjct: 59 PGTRVLDLGSGSGEMLCTWARDHGIIGTGIDMSQLFTAQAKLRAEELGVADRVTFIHGDA 118 Query: 125 FTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYK 184 + + + + + L+P G ++ G PY Sbjct: 119 SGYVSDDKAGVAACVGA--TWIGGGVAGTIELLARSLRPGGIILI----------GEPYW 166 Query: 185 VDVSTFEEV 193 V E+V Sbjct: 167 RQVPPTEDV 175 >2AVN-A nrPDB Length = 260 Score = 38.2 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 41/117 (35%), Gaps = 9/117 (7%) Query: 53 TPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSP 112 LI ++ R L G G G + + VV +D S+ L A E Sbjct: 41 HRLIGSFLEEYLKNPCRVLDLGGGTGKWSLFLQERGFEVVLVDPSKEMLEVAREKGVK-- 98 Query: 113 KAEYFSFVKEDVFTWR-PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 + V+ P+ F+ + + A+++ + +L PDG LI Sbjct: 99 -----NVVEAKAEDLPFPSGAFEAVLALGDVLSYVENKDKAFSE-IRRVLVPDGLLI 149 >1UWV-A nrPDB Length = 433 Score = 38.2 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 27/59 (45%), Gaps = 1/59 (1%) Query: 66 PLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 P R L CG G+ + +A+ VVG++ + + K + + + +F E++ Sbjct: 286 PEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGL-QNVTFYHENL 343 >1KP9-A nrPDB Length = 287 Score = 38.2 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 35/162 (21%), Positives = 59/162 (36%), Gaps = 9/162 (5%) Query: 40 WEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVV-AMASPERFVVGLDISE 98 +E + + + + + L P L GCG G ++ A+ + VVGL +S+ Sbjct: 38 FERDDMTLQEAQIAKIDLALGKLGLQPGMTLLDVGCGWGATMMRAVEKYDVNVVGLTLSK 97 Query: 99 SALAKANETYGSSPKAEYFSFVKEDVFTWRPTEL-FDLIFDYVFFCAIEPEMRPAWAKSM 157 +AN +E + + W + D I F E A+ Sbjct: 98 ---NQANHVQQLVANSENLRSKRVLLAGWEQFDEPVDRIVSIGAFEHFGHERYDAFFSLA 154 Query: 158 YELLKPDG----ELITLMYPITDHVGGPPYKVDVSTFEEVLV 195 + LL DG IT ++P H G P + F + +V Sbjct: 155 HRLLPADGVMLLHTITGLHPKEIHERGLPMSFTFARFLKFIV 196 >1G6Q-1 nrPDB Length = 328 Score = 38.2 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 40/104 (38%), Gaps = 8/104 (7%) Query: 70 ALVPGCGGGHDVVAMASPERF-VVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 L GCG G + A V+G+D+S S + A E + ++ + ++ + Sbjct: 42 VLDVGCGTGILSMFAAKHGAKHVIGVDMS-SIIEMAKELVELNGFSDKITLLRGKLEDVH 100 Query: 129 -PTELFDLIFDY--VFFCAIEPEMRP-AWAKSMYELLKPDGELI 168 P D+I +F E M +A+ Y L G + Sbjct: 101 LPFPKVDIIISEWMGYFLLYESMMDTVLYARDHY--LVEGGLIF 142 >5H02-A nrPDB Length = 283 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 35/153 (22%), Positives = 47/153 (30%), Gaps = 13/153 (8%) Query: 19 TPEEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGG 78 T E V+ F+ K E WE E E +I L + + + L G G Sbjct: 43 TNEYVSGFVDKWDELIDWESRAESE--------GDTIINILKERG---VKKVLDVATGTG 91 Query: 79 HDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFD 138 + V + VV D S L KA + + FD I Sbjct: 92 FNSVRLLQAGFDVVSADGSAEMLVKAFDNARDHGYLMRTVQADWRWMNKDIHDKFDAIVC 151 Query: 139 YV--FFCAIEPEMRPAWAKSMYELLKPDGELIT 169 F + R Y LLK DG L+ Sbjct: 152 LGNSFTHLFDEGDRRKALAEFYALLKHDGVLLL 184 >4F86-A nrPDB Length = 320 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 47/152 (30%), Gaps = 21/152 (13%) Query: 33 EGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASP-ERFV 91 +GG+E E+ + +A L+ HL P + GCG G +V V Sbjct: 94 DGGYEARLIAELHRLESAQAEFLLDHLGPVG--PGDTLVDAGCGRGGSMVMAHQRFGCKV 151 Query: 92 VGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRP 151 G+ +S + N ++ ++ D F+ A Sbjct: 152 EGVTLSAAQAEFGNRRARELGIDDHVRSRVCNML--------DTPFEKGTVAASWNNESS 203 Query: 152 AWAKSMY-------ELLKPDGELITL--MYPI 174 + ++ L+ G +T+ + Sbjct: 204 MYVD-LHDVFAEHSRFLRVGGRYVTVTGCWNP 234 >3LBF-A nrPDB Length = 210 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 29/171 (16%), Positives = 53/171 (30%), Gaps = 23/171 (13%) Query: 29 KTVEEGGWEKCWEEEITPWDQGR--ATPLIVHLV-DTSSL-PLGRALVPGCGGGHDVVAM 84 K V+E +K W+ P QG+ + P +V + + L P R L G G G+ + Sbjct: 36 KFVDEAFEQKAWDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAIL 95 Query: 85 ASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIF------- 137 A + V ++ + +A + + + W+ FD I Sbjct: 96 AHLVQHVCSVERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPE 155 Query: 138 ---------DYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVG 179 D + + + + + GE I V Sbjct: 156 IPTALMTQLDEGGILVLPVGEEHQY---LKRVRRRGGEFIIDTVEAVRFVP 203 >6G4W-q nrPDB Length = 281 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 24/51 (47%), Gaps = 3/51 (5%) Query: 60 VDTSSLPLGR---ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANET 107 ++ LP + L GCG G ++ + VGLDIS + L +A + Sbjct: 44 LELLYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDR 94 >4RYL-A nrPDB Length = 340 Score = 37.4 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 50/135 (37%), Gaps = 16/135 (11%) Query: 70 ALVPGCGGGHDVVAMASPE-RFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 L GCG G + A + V+G+D SE L +A + + + + +K + Sbjct: 68 VLDVGCGTGILSMFAAKAGAKKVLGVDQSEI-LYQAMDIIRLNKLEDTITLIKGKIEEVH 126 Query: 129 -PTELFDLIFDY--VFFCAIEP-EMRPAWAKSMYELLKPDGE----LITLMY----PITD 176 P E D+I +F E +AK+ + L G + T+ + Sbjct: 127 LPVEKVDVIISEWMGYFLLFESMLDSVLYAKN--KYLAKGGSVYPDICTISLVAVSDVNK 184 Query: 177 HVGGPPYKVDVSTFE 191 H + DV F+ Sbjct: 185 HADRIAFWDDVYGFK 199 >3VC2-A nrPDB Length = 312 Score = 37.0 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 46/153 (30%), Gaps = 21/153 (13%) Query: 32 EEGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASP-ERF 90 E +EK E+ + +A L+ HL P + GCG G +V Sbjct: 85 EHSEYEKKVIAELHRLESAQAEFLMDHLGQAG--PDDTLVDAGCGRGGSMVMAHRRFGSR 142 Query: 91 VVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMR 150 V G+ +S + N ++ ++ D FD A Sbjct: 143 VEGVTLSAAQADFGNRRARELRIDDHVRSRVCNML--------DTPFDKGAVTASWNNES 194 Query: 151 PAWAKSMY-------ELLKPDGELITL--MYPI 174 + ++ LK G +T+ + Sbjct: 195 TMYVD-LHDLFSEHSRFLKVGGRYVTITGCWNP 226 >1DUS-A nrPDB Length = 194 Score = 37.0 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 39/101 (38%), Gaps = 11/101 (10%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR- 128 L GCG G +A+A + DI+ A+ A E D + R Sbjct: 56 ILDLGCGYGVIGIALADEVKSTTMADINRRAIKLAKEN---------IKLNNLDNYDIRV 106 Query: 129 -PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 ++L++ + D + I A + ++ +++ EL+ Sbjct: 107 VHSDLYENVKDRKYNKIITNPPIRAGKEVLHRIIEEGKELL 147 >3BXO-A nrPDB Length = 239 Score = 37.0 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 37/116 (31%), Gaps = 8/116 (6%) Query: 56 IVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAE 115 I LV + + L CG G + GL++SE L A + + Sbjct: 30 IADLVRSRTPEASSLLDVACGTGTHLEHFTKEFGDTAGLELSEDMLTHARKRLPDATLH- 88 Query: 116 YFSFVKEDVFTWRPTELFDLIFD--YVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 + D+ +R F + E A S E L+P G ++ Sbjct: 89 -----QGDMRDFRLGRKFSAVVSMFSSVGYLKTTEELGAAVASFAEHLEPGGVVVV 139 >2IH5-A nrPDB Length = 421 Score = 36.7 bits (83), Expect = 0.008, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 30/93 (32%), Gaps = 14/93 (15%) Query: 49 QGRATPLIVHLVDTSS-LPLGRALVPGCGGGHDVVAMA---SPERFVVGLDISESALAKA 104 ++ +V + GR L P C G + A VG++I AL Sbjct: 21 VETPPEVVDFMVSLAEAPRGGRVLEPACAHGPFLRAFREAHGTAYRFVGVEIDPKALD-- 78 Query: 105 NETYGSSPKAEYFSFVKEDVFTWRPTELFDLIF 137 P + D W P E FDLI Sbjct: 79 ------LPPWA--EGILADFLLWEPGEAFDLIL 103 >3LDU-A nrPDB Length = 385 Score = 36.7 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 27/79 (34%), Gaps = 5/79 (6%) Query: 90 FVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEM 149 + G DI E ++ A E + EY F D ++ + F I + Sbjct: 259 KIYGYDIDEESIDIARENAEIAGVDEYIEFNVGDATQFKSEDEFGFIITNPPY-----GE 313 Query: 150 RPAWAKSMYELLKPDGELI 168 R S+ +L K G Sbjct: 314 RLEDKDSVKQLYKELGYAF 332 >2H1R-A nrPDB Length = 299 Score = 36.3 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 20/54 (37%), Gaps = 1/54 (1%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKED 123 L GCG G+ V + + V+ +DI +++ + + D Sbjct: 46 VLEIGCGTGNLTVKLLPLAKKVITIDIDSRMISEVKKRCLYEG-YNNLEVYEGD 98 >5E2B-A nrPDB Length = 241 Score = 36.3 bits (82), Expect = 0.011, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 40/102 (39%), Gaps = 3/102 (2%) Query: 70 ALVPGCGGGHDVV-AMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 AL G G G + R V +DI+E L +A G K ++ + + Sbjct: 83 ALDCGAGIGRITKRLLLPLFREVDMVDITEDFLVQAKTYLGEEGKRVR-NYFCCGLQDFT 141 Query: 129 PT-ELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 P + +D+I+ + + + + L+P+G ++ Sbjct: 142 PEPDSYDVIWIQWVIGHLTDQHLAEFLRRCKGSLRPNGIIVI 183 >1F3L-A nrPDB Length = 321 Score = 35.9 bits (81), Expect = 0.014, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 48/134 (35%), Gaps = 16/134 (11%) Query: 70 ALVPGCGGGHDVVAMASPE-RFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 L GCG G + A + V+ +D SE L +A + + + +K + Sbjct: 49 VLDVGCGTGILSMFAAKAGAKKVIAVDQSEI-LYQAMDIIRLNKLEDTIVLIKGKIEEVS 107 Query: 129 -PTELFDLIFDY--VFFCAIEP-EMRPAWAKSMYELLKPDGE----LITLMY----PITD 176 P E D+I +F E +AKS + L G + T+ ++ Sbjct: 108 LPVEKVDVIISEWMGYFLLFESMLDSVLYAKS--KYLAKGGSVYPDICTISLVAVSDVSK 165 Query: 177 HVGGPPYKVDVSTF 190 H + DV F Sbjct: 166 HADRIAFWDDVYGF 179 >2YXD-A nrPDB Length = 183 Score = 35.9 bits (81), Expect = 0.016, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 24/65 (36%), Gaps = 6/65 (9%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRP 129 + GCG G V +A +FV +D + A+ + F+ + R Sbjct: 39 VVDVGCGSGGMTVEIAKRCKFVYAIDYLDGAIEVTKQNL------AKFNIKNCQIIKGRA 92 Query: 130 TELFD 134 ++ D Sbjct: 93 EDVLD 97 >4QNV-A nrPDB Length = 323 Score = 35.9 bits (81), Expect = 0.016, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 36/119 (30%), Gaps = 15/119 (12%) Query: 33 EGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFV- 91 + W W+ WD+ S L L GCG G+ + M + Sbjct: 102 DTEWRSDWK-----WDRVLPH--------LSDLTGRTILDVGCGSGYHMWRMIGAGAHLA 148 Query: 92 VGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYV-FFCAIEPEM 149 VG+D ++ L + + + + + FD +F + P Sbjct: 149 VGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLE 207 >3JWJ-A nrPDB Length = 202 Score = 35.5 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 44/110 (40%), Gaps = 11/110 (10%) Query: 69 RALVPGCGGGHDVVAMASPERF--VVGLDISESALAKANETYGS----SPKAEYFSFVKE 122 R + GCG G+ + + F + G+D+S +L A E + E ++ Sbjct: 22 RVIDLGCGQGNLLKILLKDSFFEQITGVDVSYRSLEIAQERLDRLRLPRNQWERLQLIQG 81 Query: 123 DV-FTWRPTELFD--LIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 + + + +D + + + + A+ + ++E +P ++T Sbjct: 82 ALTYQDKRFHGYDAATVIEVIEHLDLS--RLGAFERVLFEFAQPKIVIVT 129 >3EGE-A nrPDB Length = 261 Score = 35.5 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 51/121 (42%), Gaps = 10/121 (8%) Query: 55 LIVHLVDTSSLPLGRAL-VPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPK 113 ++ +++ +LP G + G G G VA+A+ FV ++ S + P+ Sbjct: 22 IVNAIINLLNLPKGSVIADIGAGTGGYSVALANQGLFVYAVEPS----IVMRQQAVVHPQ 77 Query: 114 AEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYP 173 E+F+ E++ P + D + + + + M +++ DG ++ L + Sbjct: 78 VEWFTGYAENLA--LPDKSVDGVISILAIHHFSHLEKSF--QEMQRIIR-DGTIVLLTFD 132 Query: 174 I 174 I Sbjct: 133 I 133 >4A6D-A nrPDB Length = 353 Score = 34.7 bits (78), Expect = 0.029, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 34/112 (30%), Gaps = 5/112 (4%) Query: 72 VPGCGGGHDVVAMAS--PERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRP 129 G G G S P + DI + A + + + E F + D F P Sbjct: 185 DLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTAKQHFSFQEE-EQIDFQEGDFFK-DP 241 Query: 130 TELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGP 181 DL + +Y KP G ++ + + + GP Sbjct: 242 LPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGP 293 >3V4C-A nrPDB Length = 528 Score = 34.7 bits (78), Expect = 0.036, Method: Composition-based stats. Identities = 34/176 (19%), Positives = 46/176 (26%), Gaps = 24/176 (13%) Query: 48 DQGRA---TPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKA 104 D G A P I + T SL GRAL C + + V + + AL Sbjct: 244 DVGHALVQHPHIKAVGFTGSLAGGRALFDLCAARPEPIPFFGELGSVNPMFLLPEALKAR 303 Query: 105 NETYGS----------------SPKAEYFSFVKEDVFTWRPTELF-----DLIFDYVFFC 143 ET G A D FT E + Sbjct: 304 AETLGQGWAGSLTMGAGQFCTNPGIAVVIEGADADRFTTAAVEALAKVAPQTMLTDGIAK 363 Query: 144 AIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDVSTFEEVLVPIGF 199 A ++ + L P G + D + EEV P+G Sbjct: 364 AYRDGQARFATRNAVKPLLATESSGRDASPNLFETTGAQFLADHALGEEVFGPLGL 419 >2VS1-A nrPDB Length = 425 Score = 34.3 bits (77), Expect = 0.037, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 25/77 (32%), Gaps = 1/77 (1%) Query: 45 TPWDQGRATPLIVHLVDTSSLPLG-RALVPGCGGGHDVVAMASPERFVVGLDISESALAK 103 + Q + + + S L G + L G G + +A V G D +E A+ Sbjct: 268 NSFFQTNSYQAVNLVRKVSELVEGEKILDMYSGVGTFGIYLAKRGFNVKGFDSNEFAIEM 327 Query: 104 ANETYGSSPKAEYFSFV 120 A + F Sbjct: 328 ARRNVEINNVDAEFEVA 344 >1WS6-A nrPDB Length = 171 Score = 34.3 bits (77), Expect = 0.045, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 40/132 (30%), Gaps = 6/132 (4%) Query: 51 RATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGS 110 R + + GR L P G G + AS V ++ A+ E Sbjct: 26 RLRKALFDYLRLRYPRRGRFLDPFAGSGAVGLEAASEGWEAVLVEKDPEAVRLLKENVRR 85 Query: 111 SPKAEYFSFVKEDVF---TWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGEL 167 + + +VF E F + F ++ + + + L G L Sbjct: 86 TGLGARVVALPVEVFLPEAKAQGERFTVAF---MAPPYAMDLAALFGELLASGLVEAGGL 142 Query: 168 ITLMYPITDHVG 179 L +P ++ Sbjct: 143 YVLQHPKDLYLP 154 >6M83-A nrPDB Length = 263 Score = 34.0 bits (76), Expect = 0.051, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 23/59 (38%), Gaps = 2/59 (3%) Query: 47 WDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKAN 105 + + A + LV S L CG G + +A V GL++S LA A Sbjct: 33 YHREAAD--LAALVRRHSPKAASLLDVACGTGMHLRHLADSFGTVEGLELSADMLAIAR 89 >4P7C-A nrPDB Length = 322 Score = 34.0 bits (76), Expect = 0.051, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 50/146 (34%), Gaps = 24/146 (16%) Query: 42 EEITPWDQGRATPLIVHLVDTS--------------SLPLGRALVPGCGGGHDVVAMASP 87 ++PW +G + +DT L R L GCG G+ M Sbjct: 84 LGLSPWRKG-PFNVFGVHIDTEWRSDWKWSRVSPHLDLKGKRVLDVGCGNGYYQWRMLGA 142 Query: 88 ERF-VVGLDISESALA--KANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYV-FFC 143 V+G+D + +A + Y A + F ED+ E FD +F + Sbjct: 143 GADSVIGVDPNWLFFCQFQAMQRYLPDLPAWHLPFALEDLPA--NLEGFDTVFSMGVLYH 200 Query: 144 AIEPEMRPAWAKSMYELLKPDGELIT 169 P ++ + L GEL+ Sbjct: 201 RKSPIDHLL---ALKDCLVKGGELVM 223 >4KRG-A nrPDB Length = 466 Score = 34.0 bits (76), Expect = 0.053, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 33/99 (33%), Gaps = 4/99 (4%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRP 129 + G G G +A R+V+ D ES + K + S+ D + Sbjct: 61 VVDIGAGIGRFTTVLAETARWVLSTDFIESFIEK---NQERNAHMGNISYQIGDAVHLQM 117 Query: 130 TEL-FDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGEL 167 E DL+F + + + L+ DG + Sbjct: 118 DEKSVDLVFTNWLMMYLSDREVIEFLLNAMRWLRADGYI 156 >1XDU-A nrPDB Length = 374 Score = 34.0 bits (76), Expect = 0.054, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 37/103 (35%), Gaps = 4/103 (3%) Query: 70 ALVPGCGGGH--DVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTW 127 L G G G +A+ +P ++++ A +A + + A+ + + D F Sbjct: 186 VLDVGGGNGGMLAAIALRAPHLRGTLVELAGPA-ERARRRFADAGLADRVTVAEGDFFKP 244 Query: 128 RPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITL 170 P D++ E + L+P G L+ L Sbjct: 245 LPVTA-DVVLLSFVLLNWSDEDALTILRGCVRALEPGGRLLVL 286 >5WMM-A nrPDB Length = 926 Score = 33.6 bits (75), Expect = 0.068, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 44/140 (31%), Gaps = 7/140 (5%) Query: 35 GWEKCWEEEITPW-DQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVG 93 GW+ + + P + R +V + L R L G G G + +A G Sbjct: 525 GWKSSYTRDNIPLSEMRRWRDSVVE--EVRGLRARRILEIGVGSGLLLGPLAPEAEAYWG 582 Query: 94 LDISESALAKANETYGSSP-KAEYFSFVK--EDVFTWRPTELFDLIFDYVFFCAIEPEMR 150 D S + + G+ P E S DV P + FD + Sbjct: 583 TDFSLPVIERLEVQVGTDPCLKEKVSLRCQHADVADGLPVKYFDTVILNSVVQYFPDAAY 642 Query: 151 PAWA-KSMYELLKPDGELIT 169 + + L P G ++ Sbjct: 643 LSRVLDVALDRLAPGGRILV 662 >5IS8-A nrPDB Length = 381 Score = 33.6 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 26/131 (19%), Positives = 38/131 (29%), Gaps = 7/131 (5%) Query: 70 ALVPGCGGGHDVVAMASPERF-VVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 L GCG G A + ++ S A A S+ + + V Sbjct: 63 VLDVGCGSGILSFFAAQAGARKIYAVEASTMA-QHAEVLVKSNNLTDRIVVIPGKVEEVS 121 Query: 129 PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDVS 188 E D+I + E + LKP G M+P V P+ D Sbjct: 122 LPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGN----MFPTIGDVHLAPF-TDEQ 176 Query: 189 TFEEVLVPIGF 199 + E F Sbjct: 177 LYMEQFTKANF 187 >4IKP-A nrPDB Length = 341 Score = 33.6 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 26/131 (19%), Positives = 38/131 (29%), Gaps = 7/131 (5%) Query: 70 ALVPGCGGGHDVVAMASPERF-VVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 L GCG G A + ++ S A A S+ + + V Sbjct: 49 VLDVGCGSGILSFFAAQAGARKIYAVEASTMA-QHAEVLVKSNNLTDRIVVIPGKVEEVS 107 Query: 129 PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDVS 188 E D+I + E + LKP G M+P V P+ D Sbjct: 108 LPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGN----MFPTIGDVHLAPF-TDEQ 162 Query: 189 TFEEVLVPIGF 199 + E F Sbjct: 163 LYMEQFTKANF 173 >3B3J-A nrPDB Length = 480 Score = 33.6 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 26/131 (19%), Positives = 38/131 (29%), Gaps = 7/131 (5%) Query: 70 ALVPGCGGGHDVVAMASPERF-VVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 L GCG G A + ++ S A A S+ + + V Sbjct: 162 VLDVGCGSGILSFFAAQAGARKIYAVEASTMA-QHAEVLVKSNNLTDRIVVIPGKVEEVS 220 Query: 129 PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDVS 188 E D+I + E + LKP G M+P V P+ D Sbjct: 221 LPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGN----MFPTIGDVHLAPF-TDEQ 275 Query: 189 TFEEVLVPIGF 199 + E F Sbjct: 276 LYMEQFTKANF 286 >4QTT-B nrPDB Length = 208 Score = 33.6 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 32/117 (27%), Gaps = 6/117 (5%) Query: 66 PLGRALVPGCGGGHDVVAMASPERFV-VGLDISESALAKANETYGS-----SPKAEYFSF 119 P L GCG G + V GLDIS S LA F Sbjct: 47 PCSFILDIGCGSGLSGEILTQEGDHVWCGLDISPSMLATGLSRELEGDLMLQDMGTGIPF 106 Query: 120 VKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITD 176 + + + + ++Y LK G+ + YP D Sbjct: 107 RAGSFDAAISISAIQWLCNADTSYNDPKQRLMRFFNTLYAALKKGGKFVAQFYPKND 163 >1VLM-A nrPDB Length = 219 Score = 33.6 bits (75), Expect = 0.073, Method: Composition-based stats. Identities = 26/105 (24%), Positives = 38/105 (36%), Gaps = 13/105 (12%) Query: 65 LPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV 124 LP GR + G G G V + + +G++ SE A + K + +D Sbjct: 46 LPEGRGVEIGVGTGRFAVPL----KIKIGVEPSERMAEIARKRGVFVLKGTAENLPLKD- 100 Query: 125 FTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 E FD C ++ R K Y +LK G LI Sbjct: 101 ------ESFDFALMVTTICFVDDPERAL--KEAYRILKKGGYLIV 137 >3MCZ-A nrPDB Length = 352 Score = 33.2 bits (74), Expect = 0.088, Method: Composition-based stats. Identities = 21/140 (15%), Positives = 43/140 (30%), Gaps = 4/140 (2%) Query: 53 TPLIVHLVDTSSLPLGR-ALVPGCGGGHDVVAMASPERFVVG-LDISESALAKANETYGS 110 P++ + + R + G G + + + G + + A +T + Sbjct: 165 QPMVDVVSELGVFARARTVIDLAGGHGTYLAQVLRRHPQLTGQIWDLPTTRDAARKTIHA 224 Query: 111 SPKAEYFSFVKEDVFTWRPTE--LFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 F ++++ R E D++ + L+KP G L+ Sbjct: 225 HDLGGRVEFFEKNLLDARNFEGGAADVVMLNDCLHYFDAREAREVIGHAAGLVKPGGALL 284 Query: 169 TLMYPITDHVGGPPYKVDVS 188 L + D P D S Sbjct: 285 ILTMTMNDDRVTPALSADFS 304 >4HG2-A nrPDB Length = 257 Score = 33.2 bits (74), Expect = 0.090, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 43/131 (32%), Gaps = 9/131 (6%) Query: 49 QGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETY 108 + R + + + G AL GCG G + +A V +D E+ + +A Sbjct: 22 RPRYPRALFRWLGEVAPARGDALDCGCGSGQASLGLAEFFERVHAVDPGEAQIRQA---- 77 Query: 109 GSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 P+ Y + + P + D+ + + A + + +P Sbjct: 78 LRHPRVTY-AVAPAEDTGLPPASV-DVAIAAQAMHWFDLDRFWAE---LRRVARPGAVFA 132 Query: 169 TLMYPITDHVG 179 + Y +T Sbjct: 133 AVTYGLTRVDP 143 >3GRV-A nrPDB Length = 295 Score = 33.2 bits (74), Expect = 0.091, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 36/104 (34%), Gaps = 12/104 (11%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRP 129 L G G G +A + V ++I +S AN+ + D Sbjct: 54 VLEIGLGKGILTEELAKNAKKVYVIEIDKSLEPYANKL---KELYNNIEIIWGDALKVDL 110 Query: 130 TEL-FDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMY 172 +L F+ + + + P ++L+K +L LMY Sbjct: 111 NKLDFNKVVANLPYQISSPI--------TFKLIKRGFDLAVLMY 146 >3FYD-A nrPDB Length = 263 Score = 33.2 bits (74), Expect = 0.091, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 36/104 (34%), Gaps = 12/104 (11%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRP 129 L G G G +A + V ++I +S AN+ + D Sbjct: 25 VLEIGLGKGILTEELAKNAKKVYVIEIDKSLEPYANKL---KELYNNIEIIWGDALKVDL 81 Query: 130 TEL-FDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMY 172 +L F+ + + + P ++L+K +L LMY Sbjct: 82 NKLDFNKVVANLPYQISSPI--------TFKLIKRGFDLAVLMY 117 >3R0Q-C nrPDB Length = 376 Score = 33.2 bits (74), Expect = 0.092, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 45/125 (36%), Gaps = 7/125 (5%) Query: 70 ALVPGCGGGHDVVAMASPERF-VVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 L G G G + A V ++ ++ A A ++ ++ V Sbjct: 67 VLDVGTGSGILAIWSAQAGARKVYAVEATKMA-DHARALVKANNLDHIVEVIEGSVEDIS 125 Query: 129 PTELFDLIF-DYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDV 187 E D+I +++ + + M + + LKP G +MYP + P K ++ Sbjct: 126 LPEKVDVIISEWMGYFLLRESMFDSVISARDRWLKPTG----VMYPSHARMWLAPIKSNI 181 Query: 188 STFEE 192 + + Sbjct: 182 ADRKR 186 >4DCM-A nrPDB Length = 375 Score = 33.2 bits (74), Expect = 0.096, Method: Composition-based stats. Identities = 29/164 (17%), Positives = 53/164 (32%), Gaps = 17/164 (10%) Query: 25 TFLHKTVEEGGWEKCWEEEITPWDQGRATPLIV-------HLVDTSSLPL---GRALVPG 74 TF + + W+ E T W + LP G + G Sbjct: 171 TFNEPQLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLG 230 Query: 75 CGGGHDVVAM--ASPERFVVGLDISESALAKANETYGSS--PKAEYFSFVKEDVFTWRPT 130 CG G + + +P+ VV +D S A+A + ++ + F+ + + Sbjct: 231 CGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEP 290 Query: 131 ELFDLIFDYVFF---CAIEPEMRPAWAKSMYELLKPDGELITLM 171 F+ + F A+ + LK +GEL + Sbjct: 291 FRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIVA 334 >1QAM-A nrPDB Length = 244 Score = 32.8 bits (73), Expect = 0.11, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 29/90 (32%), Gaps = 4/90 (4%) Query: 69 RALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 G G GH + + FV ++I T + F + +D+ ++ Sbjct: 33 NIFEIGSGKGHFTLELVQRCNFVTAIEIDHK---LCKTTENKLVDHDNFQVLNKDILQFK 89 Query: 129 -PTELFDLIFDYVFFCAIEPEMRPAWAKSM 157 P IF + + +R S+ Sbjct: 90 FPKNQSYKIFGNIPYNISTDIIRKIVFDSI 119 >1L1E-A nrPDB Length = 287 Score = 32.8 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 39/108 (36%), Gaps = 9/108 (8%) Query: 66 PLGRALVPGCGGGHDV-VAMASPERFVVGLDISESALAKANETYGS--SPKAEYFSFVKE 122 P L GCG G + A+ + VVGL +SE+ + + +P++ Sbjct: 64 PGMTLLDIGCGWGATMRRAIEKYDVNVVGLTLSENQAGHVQKMFDQMDTPRSRRVLLE-- 121 Query: 123 DVFTWRPTEL-FDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 W + D I F + + + + L DG+++ Sbjct: 122 ---GWEKFDEPVDRIVSIGAFEHFGHQRYHHFFEVTHRTLPADGKMLL 166 >3HTX-A nrPDB Length = 950 Score = 32.8 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 54/145 (37%), Gaps = 14/145 (9%) Query: 44 ITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERF---VVGLDISESA 100 P + R + H+ ++S+ + GCG G + ++ ++G+DIS Sbjct: 702 KPPLSKQRVEYALKHIRESSA---STLVDFGCGSGSLLDSLLDYPTSLQTIIGVDISPKG 758 Query: 101 LAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYE- 159 LA+A + + +V + + L FD ++ + M E Sbjct: 759 LARA-----AKMLHVKLNKEACNVKSATLYDGSILEFDSRL-HDVDIGTCLEVIEHMEED 812 Query: 160 -LLKPDGELITLMYPITDHVGGPPY 183 + ++++L +P V P Y Sbjct: 813 QACEFGEKVLSLFHPKLLIVSTPNY 837 >6GKZ-A nrPDB Length = 351 Score = 32.0 bits (71), Expect = 0.20, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 33/102 (32%), Gaps = 4/102 (3%) Query: 39 CWEEEITPWDQGRATPLIVHLVDTSSLPLGR-ALVPGCGGGHDVVAMAS--PERFVVGLD 95 C+ +E + ++ + + + G+ L GCG G + +A V + Sbjct: 95 CYFKEDSTTLDEAEIAMLDLYCERAQIQDGQSVLDLGCGQGALTLHVAQKYKNCRVTAVT 154 Query: 96 ISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIF 137 S + + E D+ T E +D I Sbjct: 155 NS-VSQKEYIEEESRRRNLLNVEVKLADITTHEMAETYDRIL 195 >5Y4R-A nrPDB Length = 294 Score = 31.6 bits (70), Expect = 0.25, Method: Composition-based stats. Identities = 23/176 (13%), Positives = 48/176 (27%), Gaps = 44/176 (25%) Query: 37 EKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMA----------- 85 E W + P++ + ++ L+ + R C G + +++ Sbjct: 93 ETLWFRDTYPFEVLK-QRVLPELIKANGGQRLRIWSAACSSGQEPYSLSMAIDEFEKTNL 151 Query: 86 ---SPERFVVGLDISESALAKANETYGSS---------------------PKAEY----- 116 +V D+S S L A + + Sbjct: 152 GQLKAGVQIVATDLSGSMLTAAKAGEYDTLAMGRGLSPERLQRYFDAKGPGRWAVKPAIR 211 Query: 117 --FSFVKEDVFT-WRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELIT 169 F ++ + FD++F E++ ++ LKP G L Sbjct: 212 SRVEFRALNLLDSYASLGKFDMVFCRNVLIYFSAEVKRDILLRIHGTLKPGGYLFL 267 >3BKX-A nrPDB Length = 275 Score = 31.6 bits (70), Expect = 0.25, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 28/86 (32%), Gaps = 9/86 (10%) Query: 66 PLGRALVPGCGGGHDVVAMASPERF---VVGLDI------SESALAKANETYGSSPKAEY 116 P + L GCG G +A V G+DI + L +A + P + Sbjct: 43 PGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDIASPDYGAPLTLGQAWNHLLAGPLGDR 102 Query: 117 FSFVKEDVFTWRPTELFDLIFDYVFF 142 + + + D FD V Sbjct: 103 LTVHFNTNLSDDLGPIADQHFDRVVL 128 >1YUB-A nrPDB Length = 245 Score = 31.6 bits (70), Expect = 0.26, Method: Composition-based stats. Identities = 9/69 (13%), Positives = 24/69 (34%), Gaps = 5/69 (7%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDV--FTW 127 G G GH +A + V +++ N + + + +D+ F + Sbjct: 33 VYEIGTGKGHLTTKLAKISKQVTSIELDSHLF---NLSSEKLKLNTRVTLIHQDILQFQF 89 Query: 128 RPTELFDLI 136 + + ++ Sbjct: 90 PNKQRYKIV 98 >5XJ2-A nrPDB Length = 454 Score = 31.3 bits (69), Expect = 0.34, Method: Composition-based stats. Identities = 10/66 (15%), Positives = 24/66 (36%), Gaps = 1/66 (1%) Query: 50 GRATPLIVHLVDTSSLPLGRAL-VPGCGGGHDVVAMASPERFVVGLDISESALAKANETY 108 A L +D + L + G G +++A + V G+++ A+ + + Sbjct: 287 EMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNA 346 Query: 109 GSSPKA 114 + Sbjct: 347 SLNKIT 352 >2ZIG-A nrPDB Length = 297 Score = 31.3 bits (69), Expect = 0.35, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 39/117 (33%), Gaps = 9/117 (7%) Query: 13 GGNVIPTPEE-VATFLHKTVEEGGWEKCWEEEITPWDQGRATP------LIVHLVDTSSL 65 GG PT E+ + L K + + W + P + + P L LV S Sbjct: 177 GGYRKPTQEQREKSRLPKEDFHRFFRQIW--DDIPGESTKDHPAPFPLELAERLVRMFSF 234 Query: 66 PLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKE 122 L P G G ++A A R +G+++ A E + + Sbjct: 235 VGDVVLDPFAGTGTTLIAAARWGRRALGVELVPRYAQLAKERFAREVPGFSLEVLDG 291 >1XTP-A nrPDB Length = 254 Score = 30.9 bits (68), Expect = 0.46, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 33/102 (32%), Gaps = 3/102 (2%) Query: 68 GRALVPGCGGGHDVVAMASPERFVVGL-DISESALAKANETYGSSPKAEYFSFVKEDVFT 126 RAL G G G + + L + + L +A P ++ + T Sbjct: 95 SRALDCGAGIGRITKNLLTKLYATTDLLEPVKHMLEEAKRELAGMPVGKFI-LASMETAT 153 Query: 127 WRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 P +DLI + + K + L P+G + Sbjct: 154 LPP-NTYDLIVIQWTAIYLTDADFVKFFKHCQQALTPNGYIF 194 >2PBF-A nrPDB Length = 227 Score = 30.9 bits (68), Expect = 0.48, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 55/149 (36%), Gaps = 24/149 (16%) Query: 51 RATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMA-------SPERFVVGL----DISES 99 L + + P RA+ G G G+ V MA + +V+GL D+ Sbjct: 65 HMHALSLKRLINVLKPGSRAIDVGSGSGYLTVCMAIKMNVLENKNSYVIGLERVKDLVNF 124 Query: 100 ALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWA-KSMY 158 +L K + F + ++++ E +L F AI + + + Sbjct: 125 SLENIKRDKPELLKIDNFKIIHKNIYQVNEEEKKEL----GLFDAIHVGASASELPEILV 180 Query: 159 ELLKPDGELIT--------LMYPITDHVG 179 +LL +G+LI ++Y IT G Sbjct: 181 DLLAENGKLIIPIEEDYTQVLYEITKKNG 209 >2X1E-A nrPDB Length = 357 Score = 30.5 bits (67), Expect = 0.61, Method: Composition-based stats. Identities = 9/68 (13%), Positives = 24/68 (35%), Gaps = 5/68 (7%) Query: 53 TPLIVHLVDTSSLPLG--RALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGS 110 + ++++S R + G G M GL+ S +++ K + Sbjct: 182 HIALRIALESTSPSQAYDRIVEQG-GMAASAFIMVGNGHEAFGLEFSPTSIRKQVL--DA 238 Query: 111 SPKAEYFS 118 + + + + Sbjct: 239 NGRMVHTN 246 >5X62-A nrPDB Length = 406 Score = 30.5 bits (67), Expect = 0.66, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 20/42 (47%) Query: 56 IVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDIS 97 +V + T S P L+PGCG G +V ++ G + S Sbjct: 134 LVPFLKTLSPPKADILIPGCGTGRLLVDLSRMGYNCEGNEFS 175 >3HEM-A nrPDB Length = 302 Score = 30.5 bits (67), Expect = 0.66, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 51/153 (33%), Gaps = 18/153 (11%) Query: 9 DQSNGGNVIPTPEEVATFLHKTVEEGG-WEK------CWEEEITPWDQGRATPLIVHL-V 60 D ++G + P E V + K+ E W C E A L + Sbjct: 6 DTTSGTQLKPPVEAVRSHYDKSNEFFKLWLDPSMTYSCAYFERPDMTLEEAQYAKRKLAL 65 Query: 61 DTSSLPLG-RALVPGCGGGHDVVA-MASPERFVVGLDISESALAKANETYGS--SPKAEY 116 D +L G L GCG G + +A + V+GL +SE+ A + SP+ + Sbjct: 66 DKLNLEPGMTLLDIGCGWGSTMRHAVAEYDVNVIGLTLSENQYAHDKAMFDEVDSPRRKE 125 Query: 117 FSFVKEDVFTWRPTEL-FDLIFDYVFFCAIEPE 148 + W + D I F Sbjct: 126 VR-----IQGWEEFDEPVDRIVSLGAFEHFADG 153 >3MTI-A nrPDB Length = 185 Score = 30.1 bits (66), Expect = 0.72, Method: Composition-based stats. Identities = 22/119 (18%), Positives = 42/119 (35%), Gaps = 10/119 (8%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPK--AEYFSFVKEDVFTW 127 + G G+D +A + V D+ E AL K ++ E E++ + Sbjct: 26 VVDATMGNGNDTAFLAGLSKKVYAFDVQEQALGKTSQRLSDLGIENTELILDGHENLDHY 85 Query: 128 RPTELFDLIFDYVFF------CAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGG 180 + IF+ + +P + + + L+ G L ++Y H GG Sbjct: 86 VREPIRAAIFNLGYLPSADKSVITKPHTTLEAIEKILDRLEVGGRLAIMIY--YGHDGG 142 >1WG8-A nrPDB Length = 285 Score = 30.1 bits (66), Expect = 0.90, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 20/52 (38%), Gaps = 1/52 (1%) Query: 55 LIVHLVDTSSLPLGRA-LVPGCGGGHDVVAMASPERFVVGLDISESALAKAN 105 L +D ++ G + GG + V+GLD A+A+A Sbjct: 10 LYQEALDLLAVRPGGVYVDATLGGAGHARGILERGGRVIGLDQDPEAVARAK 61 >3CO8-A nrPDB Length = 380 Score = 29.7 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 18/36 (50%) Query: 158 YELLKPDGELITLMYPITDHVGGPPYKVDVSTFEEV 193 L+ G+ +Y + H G PP+K+ V+ + + Sbjct: 331 VTLIGKSGKYENTLYDLHKHSGVPPWKITVAFSDRL 366 >6IFV-A nrPDB Length = 215 Score = 29.3 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 41/118 (34%), Gaps = 8/118 (6%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRP 129 + G G G +A + VV +I + L +T E + + +DV Sbjct: 52 VIEIGPGIGALTEQLAKRAKKVVAFEIDQRLLPILKDTLSP---YENVTVIHQDVLKADV 108 Query: 130 TELFDLIF---DYVFFCAIEP--EMRPAWAKSMYELLKPDGELITLMYPITDHVGGPP 182 + + F D + A P P K + E L G ++ L + + + P Sbjct: 109 KSVIEEQFQDCDEIMVVANLPYYVTTPIIMKLLEEHLPLKGIVVMLQKEVAERMAADP 166 >3B5I-A nrPDB Length = 374 Score = 29.3 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 15/30 (50%) Query: 57 VHLVDTSSLPLGRALVPGCGGGHDVVAMAS 86 VHL ++S P A+ GC G + V + Sbjct: 43 VHLNSSASPPPFTAVDLGCSSGANTVHIID 72 >3JWI-A nrPDB Length = 207 Score = 29.3 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 42/102 (41%), Gaps = 7/102 (6%) Query: 69 RALVPGCGGGHDVVAMASPERF--VVGLDISESALAKANE--TYGSSPKA--EYFSFVKE 122 + + GCG G+ + + + F + G+D+S S L +A + P+ + S + Sbjct: 30 KVIDLGCGEGNLLSLLLKDKSFEQITGVDVSYSVLERAKDRLKIDRLPEMQRKRISLFQS 89 Query: 123 D-VFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKP 163 V+ + +D ++ A+ K ++E +P Sbjct: 90 SLVYRDKRFSGYDAATVIEVIEHLDENRLQAFEKVLFEFTRP 131 >3CKK-A nrPDB Length = 235 Score = 29.3 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 28/67 (41%), Gaps = 2/67 (2%) Query: 32 EEGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMAS--PER 89 EE W + + E P Q ++ + + GCG G +V ++ P+ Sbjct: 12 EEMDWSELYPEFFAPLTQNQSHDDPKDKKEKRAQAQVEFADIGCGYGGLLVELSPLFPDT 71 Query: 90 FVVGLDI 96 ++GL+I Sbjct: 72 LILGLEI 78 >2B5D-X nrPDB Length = 528 Score = 29.0 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 25/65 (38%), Gaps = 2/65 (3%) Query: 1 MAEEQQNSDQSNGGNVIPTPEEV--ATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVH 58 + E ++ VI T EEV AT + GG+ + W W +I Sbjct: 370 LVNESKDLKLVTASEVIDTLEEVQIATPADSSWGAGGYYETWLNGTNDWIYRHLHEMIER 429 Query: 59 LVDTS 63 ++D S Sbjct: 430 MIDLS 434 >6IFX-A nrPDB Length = 287 Score = 29.0 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 21/56 (37%), Gaps = 3/56 (5%) Query: 70 ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVF 125 + G G G +A + VV +I + L +T E + + +DV Sbjct: 52 VIEIGPGIGALTEQLAKRAKKVVAFEIDQRLLPILKDTLSP---YENVTVIHQDVL 104 >4PB5-A nrPDB Length = 390 Score = 29.0 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 27/75 (36%), Gaps = 13/75 (17%) Query: 73 PGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTEL 132 GC + + A VV + + +ALA + + +A + F Sbjct: 204 AGCVQAAEALRAAGLPCPVVSVGSTPTALAASRLDGVTEVRAGVYVF------------- 250 Query: 133 FDLIFDYVFFCAIEP 147 FDL+ + CA E Sbjct: 251 FDLVMRNIGVCAAED 265 >1NVM-B nrPDB Length = 312 Score = 29.0 bits (63), Expect = 2.0, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 39/114 (34%), Gaps = 16/114 (14%) Query: 90 FVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEM 149 +VG+D + LA+A ++ V+ + D +FD A Sbjct: 34 AMVGIDAASDGLARA----QRMGVTTTYAGVEG-LIKLPEFADIDFVFDATSASAHVQNE 88 Query: 150 RPAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDVSTFEEVLVPIGFKAVS 203 ++ KP LI +T GP Y V V EE L + V+ Sbjct: 89 ------ALLRQAKPGIRLI----DLTPAAIGP-YCVPVVNLEEHLGKLNVNMVT 131 >2YVL-A nrPDB Length = 248 Score = 28.6 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 32/96 (33%), Gaps = 6/96 (6%) Query: 69 RALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR 128 R L G G G + ++ V + E A + + F D ++ Sbjct: 94 RVLEFGTGSGALLAVLSEVAGEVWTFEAVEEFYKTAQKNLKKFNLGKNVKFFNVD---FK 150 Query: 129 PTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPD 164 E+ + IF F EP + + +++ L Sbjct: 151 DAEVPEGIFHAAFVDVREPWH---YLEKVHKSLMEG 183 >2EEC-A nrPDB Length = 125 Score = 28.6 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 1/49 (2%) Query: 148 EMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDVSTFEEVLVP 196 + P K MY + P LI++ Y +H+ G P+K V T + ++ P Sbjct: 69 QETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV-TGQRLVSP 116 >4RVG-A nrPDB Length = 426 Score = 28.6 bits (62), Expect = 2.2, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 42/106 (39%), Gaps = 5/106 (4%) Query: 60 VDTSSLPLGR-ALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFS 118 V+ +P G L G G + A + +G+D + + A ANE + E+FS Sbjct: 99 VERFGIPEGSFVLEIGSNTGSQLKAFQNAGMRTLGIDPARNIAAVANERGIET-LPEFFS 157 Query: 119 FVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPD 164 + ++ +VF + A A+ + +LL PD Sbjct: 158 VDTAALVKKTHGTPQLVLGRHVFAHI---DDVSAVAEGVRDLLGPD 200 >3FUV-A nrPDB Length = 271 Score = 28.6 bits (62), Expect = 2.2, Method: Composition-based stats. Identities = 14/97 (14%), Positives = 27/97 (27%), Gaps = 2/97 (2%) Query: 56 IVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAE 115 + +V+ + G G G G A+ V ++ ET P Sbjct: 36 LRRIVEAARPFTGPVFEVGPGLGALTRALLEAGAEVTAIEKDLRLRPVLEETLSGLP--V 93 Query: 116 YFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPA 152 F ++ W L+ + + P + Sbjct: 94 RLVFQDALLYPWEEVPQGSLLVANLPYHIATPLVTRL 130 >1VKN-A nrPDB Length = 351 Score = 28.6 bits (62), Expect = 2.4, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 18/45 (40%), Gaps = 7/45 (15%) Query: 172 YPITDHVGGPPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKG 216 Y + H P E+ L I K V+V PH +P +G Sbjct: 211 YNVAKHRHVP-------EMEQELGKISGKKVNVVFTPHLVPMTRG 248 >5LV5-A nrPDB Length = 403 Score = 28.6 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 33/110 (30%), Gaps = 7/110 (6%) Query: 63 SSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKE 122 ++L L G G G + A V + + +A E + + + Sbjct: 107 AALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLPG 166 Query: 123 DVFTWRPTELFDLIFD----YVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 V T E D I Y M + + + LK G L+ Sbjct: 167 PVETVELPERVDAIVSEWMGYGLLHE---SMLSSVLHARTKWLKEGGLLL 213 >6DCC-A nrPDB Length = 309 Score = 28.2 bits (61), Expect = 3.0, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 18/44 (40%), Gaps = 2/44 (4%) Query: 66 PLGRALVPGCGGGHDVVAMASP--ERFVVGLDISESALAKANET 107 L GC GH +++A +VGLDI + A + Sbjct: 63 RGRDVLDLGCNVGHLTLSIACKWGPSRMVGLDIDSRLIHSARQN 106 >5EHG-A nrPDB Length = 276 Score = 28.2 bits (61), Expect = 3.2, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 25/77 (32%), Gaps = 1/77 (1%) Query: 65 LPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKE-D 123 +P GR + GCG G A ++ ++ S+ + D Sbjct: 72 IPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKD 131 Query: 124 VFTWRPTELFDLIFDYV 140 VF P + L+ D Sbjct: 132 VFYLPPEKCDTLLCDIG 148 >4V0R-A nrPDB Length = 892 Score = 27.8 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 25/77 (32%), Gaps = 1/77 (1%) Query: 65 LPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKE-D 123 +P GR + GCG G A ++ ++ S+ + D Sbjct: 69 IPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKD 128 Query: 124 VFTWRPTELFDLIFDYV 140 VF P + L+ D Sbjct: 129 VFYLPPEKCDTLLCDIG 145 >1ZEJ-A nrPDB Length = 293 Score = 27.8 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 39/130 (30%), Gaps = 9/130 (6%) Query: 69 RALVPGCGGGHDVVAMA-SPERFVVGLDISESALAKANETYGSSPKAEYFSFV------- 120 + V G G +A+A + + VV D+SE AL A E F Sbjct: 14 KVFVIGAGLMGRGIAIAIASKHEVVLQDVSEKALEAAREQIPEE-LLSKIEFTTTLEKVK 72 Query: 121 KEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGG 180 D+ E + + + S+ + L + + H Sbjct: 73 DCDIVMEAVFEDLNTKVEVLREVERLTNAPLCSNTSVISVDDIAERLDSPSRFLGVHWMN 132 Query: 181 PPYKVDVSTF 190 PP+ + + Sbjct: 133 PPHVMPLVEI 142 >1RJ5-A nrPDB Length = 261 Score = 27.4 bits (59), Expect = 4.9, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 21/51 (41%), Gaps = 4/51 (7%) Query: 161 LKPDGELITLMYPITDHVGGPPYKVDVSTFEEVLVPIGFKAVSVEENPHAI 211 L +G + L P T H+GG P K + G S+E + H I Sbjct: 62 LHNNGHTVQLSLPPTLHLGGLPRKYTAAQLHLHWGQRG----SLEGSEHHI 108 >1VKM-A nrPDB Length = 297 Score = 27.4 bits (59), Expect = 5.0, Method: Composition-based stats. Identities = 25/131 (19%), Positives = 42/131 (32%), Gaps = 15/131 (11%) Query: 87 PERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWR------PTELFDLIFDYV 140 P R V D++E + ++A E + T T F L F Sbjct: 134 PGRVDVSQDLTEMSSSRAVLVSSGIKSILDVEATFEMLETLEIPLVGFRTNEFPLFFSR- 192 Query: 141 FFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGP---PYKVDVSTFEEVLVPI 197 + R +++ E+LK + + T V P Y++ E +L I Sbjct: 193 -----KSGRRVPRIENVEEVLKIYESMKEMELEKTLMVLNPVPEEYEIPHDEIERLLEKI 247 Query: 198 GFKAVSVEENP 208 + E P Sbjct: 248 ELEVEGKEVTP 258 >3HLK-A nrPDB Length = 446 Score = 27.0 bits (58), Expect = 5.9, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 31/99 (31%), Gaps = 7/99 (7%) Query: 93 GLDISESALAKANETYGSSPKAEYFSFVKE-----DVFTWRPTELFDLIFDYVFFCAIEP 147 G + + + A+ + D ++ P E + F ++ Sbjct: 286 GETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHN 345 Query: 148 EMRPAWAKSMYELLKPDG--ELITLMYPITDHVGGPPYK 184 +A + L+ G + + YP T H PPY Sbjct: 346 WKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYF 384 >5E9J-A nrPDB Length = 274 Score = 27.0 bits (58), Expect = 7.2, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 18/41 (43%), Gaps = 1/41 (2%) Query: 70 ALVPGCGGGHD-VVAMASPERFVVGLDISESALAKANETYG 109 L GCG G D + +V DI++ ++ + + Y Sbjct: 35 VLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQRYE 75 >3BGV-A nrPDB Length = 313 Score = 27.0 bits (58), Expect = 7.2, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 18/41 (43%), Gaps = 1/41 (2%) Query: 70 ALVPGCGGGHD-VVAMASPERFVVGLDISESALAKANETYG 109 L GCG G D + +V DI++ ++ + + Y Sbjct: 38 VLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQRYE 78 >3HXK-A nrPDB Length = 276 Score = 26.6 bits (57), Expect = 9.1, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 19/45 (42%), Gaps = 2/45 (4%) Query: 147 PEMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDVSTFE 191 AW + ++ +P G + L YP+T G P + FE Sbjct: 129 GGHLAAWYGNSEQIHRPKG--VILCYPVTSFTFGWPSDLSHFNFE 171 >3DC8-A nrPDB Length = 490 Score = 26.6 bits (57), Expect = 9.5, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 28/90 (31%), Gaps = 16/90 (17%) Query: 92 VGLDISESALAKANETYGS---SPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPE 148 + + A+ +A P ++ T TE FD +D+ + P Sbjct: 237 TSCEQAHEAIRRARAKGMRVFGEPLIQH--------LTLDETEYFDKDWDHAARRVMSPP 288 Query: 149 MR-PAWAKSMYELLKPDGELITLMYPITDH 177 R S++ L + TDH Sbjct: 289 FRNKLHQDSLWAGLASGSLQVV----ATDH 314 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.127 0.342 Lambda K H 0.267 0.0394 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,822,127 Number of Sequences: 36641 Number of extensions: 341512 Number of successful extensions: 1131 Number of sequences better than 10.0: 167 Number of HSP's better than 10.0 without gapping: 94 Number of HSP's successfully gapped in prelim test: 99 Number of HSP's that attempted gapping in prelim test: 988 Number of HSP's gapped (non-prelim): 196 length of query: 227 length of database: 10,336,785 effective HSP length: 94 effective length of query: 133 effective length of database: 6,892,531 effective search space: 916706623 effective search space used: 916706623 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 57 (26.6 bits)