BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q0PGJ6 (315 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3H7U-A nrPDB 651 0.0 5JH1-A nrPDB 464 e-131 3H7R-A nrPDB 430 e-121 2BGQ-A nrPDB 273 9e-74 2ALR-A nrPDB 254 3e-68 4GAC-A nrPDB 253 8e-68 1HQT-A nrPDB 252 1e-67 4HBK-A nrPDB 240 5e-64 1ZUA-X nrPDB 239 1e-63 1DLA-A nrPDB 231 3e-61 3RX4-A nrPDB 231 4e-61 5Z6T-A nrPDB 225 2e-59 1Q5M-A nrPDB 224 4e-59 4JQA-A nrPDB 221 3e-58 4GIE-A nrPDB 221 4e-58 1QWK-A nrPDB 220 5e-58 1C9W-A nrPDB 219 2e-57 2FVL-A nrPDB 215 2e-56 1K8C-A nrPDB 215 2e-56 5ZCM-A nrPDB 214 4e-56 5JM5-A nrPDB 211 2e-55 3O3R-A nrPDB 210 5e-55 1FRB-A nrPDB 209 1e-54 3G1R-A nrPDB 206 1e-53 1VP5-A nrPDB 204 5e-53 1VBJ-A nrPDB 203 9e-53 3KRB-A nrPDB 202 2e-52 4F40-A nrPDB 199 1e-51 1AFS-A nrPDB 198 2e-51 5UXF-A nrPDB 195 2e-50 2HE8-A nrPDB 195 2e-50 3D3F-A nrPDB 187 4e-48 4MHB-A nrPDB 186 8e-48 1MZR-A nrPDB 185 2e-47 3WCZ-A nrPDB 181 5e-46 4IJC-A nrPDB 178 3e-45 1A80-A nrPDB 169 2e-42 3UP8-A nrPDB 167 4e-42 4OTK-A nrPDB 164 4e-41 3WG6-A nrPDB 137 5e-33 4H8N-A nrPDB 129 2e-30 1PZ1-A nrPDB 74 6e-14 3EB3-A nrPDB 72 4e-13 1LQA-A nrPDB 62 4e-10 1PYF-A nrPDB 60 1e-09 3N6Q-A nrPDB 60 2e-09 1OG6-A nrPDB 48 6e-06 4R9O-A nrPDB 47 9e-06 1GVE-A nrPDB 45 4e-05 2BP1-A nrPDB 44 7e-05 2C91-A nrPDB 41 7e-04 2CLP-A nrPDB 40 0.001 2WHY-A nrPDB 33 0.21 2DLD-A nrPDB 31 0.62 2D4E-A nrPDB 31 0.62 4NZZ-A nrPDB 30 1.4 1FP7-A nrPDB 29 2.4 3GE9-A nrPDB 29 2.9 5FX0-A nrPDB 28 3.9 5FWZ-A nrPDB 28 5.1 4Q0M-A nrPDB 28 5.8 4GYK-A nrPDB 28 5.9 1J49-A nrPDB 28 6.8 5JP9-A nrPDB 28 7.3 5I4E-A nrPDB 27 8.4 >3H7U-A nrPDB Length = 335 Score = 651 bits (1680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/315 (100%), Positives = 315/315 (100%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA Sbjct: 21 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 80 Query: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK Sbjct: 81 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 140 Query: 121 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 180 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ Sbjct: 141 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 200 Query: 181 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ 240 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ Sbjct: 201 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ 260 Query: 241 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHET 300 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHET Sbjct: 261 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHET 320 Query: 301 LSPYKSIEELWDGEI 315 LSPYKSIEELWDGEI Sbjct: 321 LSPYKSIEELWDGEI 335 >5JH1-A nrPDB Length = 309 Score = 464 bits (1193), Expect = e-131, Method: Compositional matrix adjust. Identities = 220/308 (71%), Positives = 260/308 (84%), Gaps = 2/308 (0%) Query: 8 FKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFE 67 F LNTGAK PSVGLG+WQ+ PG+VG+AV AAVK GYRHIDCA++YGNEKEIG LKKLFE Sbjct: 4 FVLNTGAKIPSVGLGSWQSDPGVVGNAVYAAVKAGYRHIDCARVYGNEKEIGLALKKLFE 63 Query: 68 DRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIK 127 + VVKRED+FITSKLW H P+DVPEALN +L DLQLEY+DLYLIHWP R+KKG+ Sbjct: 64 EGVVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQLEYLDLYLIHWPFRVKKGT-NTS 122 Query: 128 PENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSW 187 PEN + D P+TW AME LYD+GKARAIGVSNFS+KKL DLL +ARVPPAV+QVECHP W Sbjct: 123 PENFVTPDFPATWGAMEKLYDAGKARAIGVSNFSSKKLGDLLAVARVPPAVDQVECHPGW 182 Query: 188 RQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGL 247 +QTKL FC+S GVHL+AYSPLGSPGTTW+ +VLK PI+ +AEKLGK+ AQVALRW + Sbjct: 183 QQTKLHSFCQSTGVHLTAYSPLGSPGTTWMNGNVLKEPIIISIAEKLGKTSAQVALRWNI 242 Query: 248 QMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHETLSPYKSI 307 QMGHSVLPKSTNE RIK+N +V+DWSIPD + AKF+EI+QARL+ G+F+V+ S YK+ Sbjct: 243 QMGHSVLPKSTNEERIKQNLDVYDWSIPDDLLAKFSEIKQARLLRGNFIVNPE-SVYKTH 301 Query: 308 EELWDGEI 315 EELWDGE+ Sbjct: 302 EELWDGEL 309 >3H7R-A nrPDB Length = 331 Score = 430 bits (1105), Expect = e-121, Method: Compositional matrix adjust. Identities = 211/315 (66%), Positives = 243/315 (77%), Gaps = 4/315 (1%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 MA I FF+LNTGAK P VGLGT+ +V A+ A+KIGYRHIDCA IYGNEKEIG Sbjct: 21 MAAPIRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGG 76 Query: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 VLKKL D VKRE+LFITSKLW DH P+DVP+AL +TL+DLQ++YVDLYLIHWPA +K Sbjct: 77 VLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK 136 Query: 121 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 180 K S+ PE L DI STWKAMEALYDSGKARAIGVSNFS+KKL DLL +ARV PAVNQ Sbjct: 137 KESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQ 196 Query: 181 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ 240 VECHP W+Q L E CKSKGVHLS YSPLGS ++ VL+NPI+ VAEKLGK+ AQ Sbjct: 197 VECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQ 256 Query: 241 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHET 300 VALRWGLQ GHSVLPKS++ R+KEN +VFDWSIP+ +F KF+ I Q + + HET Sbjct: 257 VALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHET 316 Query: 301 LSPYKSIEELWDGEI 315 YK+IEELWDGEI Sbjct: 317 HGFYKTIEELWDGEI 331 >2BGQ-A nrPDB Length = 344 Score = 273 bits (697), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 141/311 (45%), Positives = 193/311 (62%), Gaps = 11/311 (3%) Query: 8 FKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFE 67 F L +G P+VGLGTW+A A + GYRH+D A YG EKE+G LK E Sbjct: 40 FVLKSGHAMPAVGLGTWRAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAME 99 Query: 68 DRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIK 127 + R+DLF+TSK+WCT+ P+ V AL TLKDLQL+Y+DLY IHWP R+K G+ + Sbjct: 100 -AGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGA-HMP 157 Query: 128 PE--NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHP 185 PE +L D+ WK ME L G + IGV N++ KL LL A++PPAV Q+E HP Sbjct: 158 PEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHP 217 Query: 186 SWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRW 245 W+ K+ E CK G+H++AYSPLGS + ++ +P++ VA KL K+P QV ++W Sbjct: 218 GWKNDKIFEACKKHGIHITAYSPLGSS-----EKNLAHDPVVEKVANKLNKTPGQVLIKW 272 Query: 246 GLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEI-EQARLVTG-SFLVHETLSP 303 LQ G SV+PKS+ + RIKEN VF W IP+ F I ++ R++TG V++T P Sbjct: 273 ALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRVLTGEELFVNKTHGP 332 Query: 304 YKSIEELWDGE 314 Y+S ++WD E Sbjct: 333 YRSARDVWDHE 343 >2ALR-A nrPDB Length = 324 Score = 254 bits (649), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 132/281 (46%), Positives = 181/281 (64%), Gaps = 11/281 (3%) Query: 4 AITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLK 63 A + L+TG K P +GLGTW++ PG V AV A+ +GYRHIDCA IYGNE EIG LK Sbjct: 1 AASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 60 Query: 64 K-LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKG 122 + + + V RE+LF+TSKLW T H P+DV AL +TL DLQLEY+DLYL+HWP ++G Sbjct: 61 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 120 Query: 123 SVGIKPEN------LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPP 176 P+N TWKA+EAL G +A+G+SNF+++++ D+L +A V P Sbjct: 121 DNPF-PKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 179 Query: 177 AVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEK 233 AV QVECHP Q +L C+++G+ ++AYSPLGS W D +L+ P++ +AEK Sbjct: 180 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 239 Query: 234 LGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 G+SPAQ+ LRW +Q +PKS RI +N VFD++ Sbjct: 240 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTF 280 >4GAC-A nrPDB Length = 324 Score = 253 bits (646), Expect = 8e-68, Method: Compositional matrix adjust. Identities = 131/280 (46%), Positives = 180/280 (64%), Gaps = 12/280 (4%) Query: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK-LFED 68 L+TG K P +GLGTW++ PG V A+ A+ GYRHIDCA +YGNE EIG LK+ + Sbjct: 7 LHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSG 66 Query: 69 RVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKP 128 + V RE+LF+TSKLW T H P+DV AL +TL DLQLEY+DLYL+HWP ++G P Sbjct: 67 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF-P 125 Query: 129 EN------LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVE 182 +N TWKA+E L G +A+G+SNF+++++ D+L +A V PAV QVE Sbjct: 126 KNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVE 185 Query: 183 CHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLGKSPA 239 CHP Q +L C ++G+ ++AYSPLGS W D +L+ P++ +AEK G+SPA Sbjct: 186 CHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPA 245 Query: 240 QVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI-PDYM 278 Q+ LRW +Q +PKS N RI +N VFD++ P+ M Sbjct: 246 QILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEM 285 >1HQT-A nrPDB Length = 326 Score = 252 bits (644), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 128/275 (46%), Positives = 177/275 (64%), Gaps = 11/275 (4%) Query: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLF-ED 68 L+TG K P +GLGTW++ PG V A+ A+ +GYRHIDCA I+GNE EIG L++ Sbjct: 9 LHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQETVGPG 68 Query: 69 RVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKP 128 + V RE+LF+TSKLW T H P+DV AL +TL DLQLEY+DLYL+HWP ++G P Sbjct: 69 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF-P 127 Query: 129 EN------LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVE 182 +N TWKA+EAL G RA+G+SNFS++++ D+L +A V PAV QVE Sbjct: 128 KNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRPAVLQVE 187 Query: 183 CHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLGKSPA 239 CHP Q +L C+++G+ ++AYSPLGS W + +L+ P++ +AEK +SPA Sbjct: 188 CHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEKYNRSPA 247 Query: 240 QVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 Q+ LRW +Q +PKS RI +N VFD++ Sbjct: 248 QILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTF 282 >4HBK-A nrPDB Length = 344 Score = 240 bits (613), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 124/280 (44%), Positives = 174/280 (62%), Gaps = 17/280 (6%) Query: 8 FKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFE 67 K+N G P +GLGTW + PG VG AV A++IGYRH+DCA +Y NE EIG L+ Sbjct: 38 LKMNNGRSIPVIGLGTWNSPPGEVGAAVKKALEIGYRHLDCAYVYRNEAEIGEALENALN 97 Query: 68 DRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIK 127 +KRED+FITSKLW T P+ V +A TLK+L+L Y+DLYLIHWP +K G Sbjct: 98 SLRLKREDIFITSKLWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPLKHGG---- 153 Query: 128 PENLLPVD---------IP--STWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPP 176 +L P D +P TWK ME L D G ++IG+SNF+ +++ ++LE R+ P Sbjct: 154 --DLFPTDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEHCRIKP 211 Query: 177 AVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGK 236 A Q+E H ++ KL E+ +S G+ ++AY+PLGSP + K ++L P + +A + K Sbjct: 212 ANLQIEIHANFPNIKLVEYAQSVGLTVTAYAPLGSPAHSPGKVNLLTKPCVLEIAHRHKK 271 Query: 237 SPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPD 276 +PAQV LR+ LQ V+PKS RI+ENF VFD+ + + Sbjct: 272 TPAQVLLRYLLQRKLIVVPKSVTFKRIEENFQVFDFQLSN 311 >1ZUA-X nrPDB Length = 317 Score = 239 bits (610), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 129/291 (44%), Positives = 175/291 (60%), Gaps = 22/291 (7%) Query: 6 TFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 TF +L+T AK P VGLGTW++ G V +AV A+ GYRHIDCA +Y NE E+G +++ Sbjct: 4 TFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 63 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 +++ VKREDLFI SKLW T + V +A +TLKDL+L Y+D+YLIHWP K G Sbjct: 64 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSG--- 120 Query: 126 IKPENLLPVD-----------IPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA-- 172 ++L P D W+AME L D G +A+GVSNFS ++ LL Sbjct: 121 ---DDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGL 177 Query: 173 RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNM 229 + P NQVECHP Q KL ++C SKG+ ++AYSPLGSP W K + +L++P + Sbjct: 178 KYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKE 237 Query: 230 VAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFA 280 +A K K+ AQV +R+ +Q V+PKS RI EN VFD+ + D A Sbjct: 238 IAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 288 >1DLA-A nrPDB Length = 314 Score = 231 bits (589), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 134/275 (48%), Positives = 179/275 (65%), Gaps = 10/275 (3%) Query: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69 L TGAK P +GLGTW++ PG V +AV A+ +GYRHIDCA +Y NE E+G L++ + + Sbjct: 5 LYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKLQGQ 64 Query: 70 VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129 VVKREDLFI SKLWCTDH+ V A TL+DL+L+Y+DLYLIHWP K G + Sbjct: 65 VVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDPFPLD 124 Query: 130 ---NLLP--VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAVNQVE 182 N++P D TW+AME L D G +AIGVSNF+ ++ +L + PAVNQ+E Sbjct: 125 GDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIE 184 Query: 183 CHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLGKSPA 239 HP Q KL E+CKSKG+ ++AYSPLGSP W K + +L++P + +A K K+ A Sbjct: 185 VHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTA 244 Query: 240 QVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 QV +R+ +Q V+PKS RI ENF VFD+ + Sbjct: 245 QVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFEL 279 >3RX4-A nrPDB Length = 336 Score = 231 bits (588), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 130/275 (47%), Positives = 179/275 (65%), Gaps = 10/275 (3%) Query: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69 LN GAK P +GLGTW++ PG V +AV A+ +GYRHIDCA +Y NE E+G +++ ++ Sbjct: 27 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 86 Query: 70 VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGI--- 126 VVKRE+LFI SKLWCT H+ V A +TL DL+L+Y+DLYLIHWP K G Sbjct: 87 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 146 Query: 127 KPENLLPVD--IPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAVNQVE 182 + N++P D I TW AME L D G +AIG+SNF+ ++ +L + PAVNQ+E Sbjct: 147 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 206 Query: 183 CHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLGKSPA 239 CHP Q KL ++C+SKG+ ++AYSPLGSP W K + +L++P + +A K K+ A Sbjct: 207 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTA 266 Query: 240 QVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 QV +R+ +Q V+PKS RI ENF VFD+ + Sbjct: 267 QVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFEL 301 >5Z6T-A nrPDB Length = 343 Score = 225 bits (574), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 126/296 (42%), Positives = 175/296 (59%), Gaps = 18/296 (6%) Query: 9 KLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFED 68 KLN+G P+VG G W+ + + A+K GYR D A+ Y NEK +GA +KK ++ Sbjct: 30 KLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAIDE 89 Query: 69 RVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK-------- 120 +VKREDLF+TSKLW H P +V +ALNRTL DLQ++YVDL+LIH+P K Sbjct: 90 GIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLEEKY 149 Query: 121 -KGSVGIKPENLLPVDIP--STWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPA 177 G K +N D+P TWKA+E L +GK R+IGVSNF L DLL A + P+ Sbjct: 150 PPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLRGATIKPS 209 Query: 178 VNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLG-------SPGTTWLKSDVLKNPILNMV 230 V QVE HP +Q +L EF +S+G+ ++AYS G + G S + +N + + Sbjct: 210 VLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENETIKAI 269 Query: 231 AEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIE 286 A K GKSPAQV LRW Q G +++PKS R+ EN +V + + + FA A+++ Sbjct: 270 AAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKLD 325 >1Q5M-A nrPDB Length = 322 Score = 224 bits (571), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 131/311 (42%), Positives = 181/311 (58%), Gaps = 17/311 (5%) Query: 10 LNTGAKFPSVGLGTW---QASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLF 66 L+ G P +G GT+ + +A A+ G+RHID A Y NEKE+G ++ Sbjct: 9 LSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRSKI 68 Query: 67 EDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGI 126 D VKRED+F TSKLWCT H P+ V +L +LK+LQL+YVDLY+IH+P +K G V I Sbjct: 69 ADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPG-VEI 127 Query: 127 KPEN------LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAV 178 P + VDI +TW+AME D+G A++IGVSNF+ ++L +L + P Sbjct: 128 IPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVC 187 Query: 179 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGT-TWLKSD---VLKNPILNMVAEKL 234 NQVECHP Q KL EFCKSKG+ L AYS LGS W+ +L++P++ +A+K Sbjct: 188 NQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAKKH 247 Query: 235 GKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQA-RLVTG 293 ++PA +ALR+ LQ G VL KS E RIKEN VF++ +P + + R VT Sbjct: 248 QQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSEDMKVIDSLNRNFRYVTA 307 Query: 294 SFLVHETLSPY 304 F + P+ Sbjct: 308 DFAIGHPNYPF 318 >4JQA-A nrPDB Length = 331 Score = 221 bits (563), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 125/288 (43%), Positives = 176/288 (61%), Gaps = 14/288 (4%) Query: 1 MANAITFFKLNTGAKFPSVGLGTW---QASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKE 57 M + KLN G P +G GT+ + +AV A++ G+ HID A +Y NE++ Sbjct: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 58 IGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPA 117 +G ++ D VKRED+F TSKLW H P+ V AL R+LK+LQL+YVDLYLIH+P Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 118 RIKKGSVGI-KPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA 172 +K G I K EN VD+ +TW+AME D+G A++IGVSNF+ + L +L Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 173 --RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTT-WLKSD---VLKNPI 226 + P NQVECHP + Q KL +FCKSK + L AYS LGS W+ + +L++P+ Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240 Query: 227 LNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 L +A+K ++PA +ALR+ LQ G VL KS NE RI++N VF++ + Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQL 288 >4GIE-A nrPDB Length = 290 Score = 221 bits (562), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 114/283 (40%), Positives = 171/283 (60%), Gaps = 24/283 (8%) Query: 10 LNTGAKFPSVGLGTWQASPGL-VGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFED 68 L+ + P +GLG W+A G +AV A++ GYRHID A IY NE+ +G ++ + Sbjct: 18 LHNSVRMPQLGLGVWRAQDGAETANAVRWAIEAGYRHIDTAYIYSNERGVGQGIR----E 73 Query: 69 RVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKP 128 V RE++++T+K+W +D + A R+ + L LEY+DLYLIHWP + K Sbjct: 74 SGVPREEVWVTTKVWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWPGKKK-------- 125 Query: 129 ENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWR 188 TWKA+E LY+ K RAIGVSNF L +L + ++ P VNQVE HP ++ Sbjct: 126 -------FVDTWKALEKLYEEKKVRAIGVSNFEPHHLTELFKSCKIRPMVNQVELHPLFQ 178 Query: 189 QTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQ 248 Q L+EFCK + ++A+SPLGS ++ +LKN +L +A+K KSPAQV +RW +Q Sbjct: 179 QRTLREFCKQHNIAITAWSPLGSGE----EAGILKNHVLGEIAKKHNKSPAQVVIRWDIQ 234 Query: 249 MGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLV 291 G +PKSTN+GRI+ENFNV+D+ + + + E+ + + + Sbjct: 235 HGIVTIPKSTNKGRIQENFNVWDFKLTEEEMRQIDELNEDKRI 277 >1QWK-A nrPDB Length = 317 Score = 220 bits (561), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 127/311 (40%), Positives = 177/311 (56%), Gaps = 20/311 (6%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 M++A KL+ G + P +GLGTWQ+SP V AV AVK GYR ID A +Y NE+ IG Sbjct: 1 MSSATASIKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGT 60 Query: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 +K+L E+ VVKRE+LFIT+K W + P + L +LK LQLEYVDLYL H PA Sbjct: 61 AIKELLEEGVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFN 120 Query: 121 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 180 + PV+ W+ +A+Y +G A+A+GVSN++ +++ L L P +Q Sbjct: 121 D---DMSEHIASPVE--DVWRQFDAVYKAGLAKAVGVSNWNNDQISRALALGLTPVHNSQ 175 Query: 181 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLK-------------SDVLKNPIL 227 VE H + Q +FCK + +++Y+ LGSPG SD+ +L Sbjct: 176 VELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAPSDLQDQNVL 235 Query: 228 NMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQ 287 + AEK K+PAQV LR+ L G ++LPKS E RIKENF VFD+S+ + AK E + Sbjct: 236 AL-AEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTEEDIAKLEESKN 294 Query: 288 A-RLVTGSFLV 297 + RL F+ Sbjct: 295 SQRLFLQDFMT 305 >1C9W-A nrPDB Length = 315 Score = 219 bits (557), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 128/285 (44%), Positives = 177/285 (62%), Gaps = 10/285 (3%) Query: 6 TFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 TF +L+T AK P VGLGTWQ+ PG V +AV A+ GYRHIDCA Y NE E+G +++ Sbjct: 2 TFVELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEK 61 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 +++ V+REDLFI SKLW T + + + EA +TL DL+L+Y+DLYLIHWP ++ G Sbjct: 62 IKEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKEL 121 Query: 126 IKPE---NLLPVDIP--STWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAV 178 + N+L I W+ ME L D G +A+GVSNF+ ++ +L + P Sbjct: 122 FPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPVT 181 Query: 179 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLG 235 NQVECHP Q KL E+C SKG+ ++AYSPLGSP W K + +L++P + +A K Sbjct: 182 NQVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKHK 241 Query: 236 KSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFA 280 K+ AQV +R+ +Q V+PKS RI ENF VFD+ + D A Sbjct: 242 KTSAQVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMA 286 >2FVL-A nrPDB Length = 324 Score = 215 bits (548), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 121/280 (43%), Positives = 172/280 (61%), Gaps = 14/280 (5%) Query: 9 KLNTGAKFPSVGLGTWQASPGLVGDAVAA---AVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 +LN G P +G GT+ AV A++ G+RHID A +Y NE+++G ++ Sbjct: 10 ELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSK 69 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 D VKRED+F TSKLWCT PQ V AL +LK LQL+YVDLYL+H+P +K G Sbjct: 70 IADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETP 129 Query: 126 I-KPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAV 178 + K EN VD+ +TW+ ME D+G A++IGVSNF+ ++L +L + P Sbjct: 130 LPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVC 189 Query: 179 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSP-GTTWLKSD---VLKNPILNMVAEKL 234 NQVECHP Q+KL +FCKSK + L A+S LG+ W+ + +L++P+L +A+K Sbjct: 190 NQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKH 249 Query: 235 GKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 ++PA +ALR+ LQ G VL KS NE RI+EN VF++ + Sbjct: 250 KRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQL 289 >1K8C-A nrPDB Length = 322 Score = 215 bits (548), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 124/297 (41%), Positives = 173/297 (58%), Gaps = 20/297 (6%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 M+ +I KL++G PS+G G W+ + G+ V A+K GYR D A+ YGNEKE+G Sbjct: 1 MSASIPDIKLSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGD 60 Query: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 +K+ ++ +VKRE++F+TSKLW HDP++V ALN+TL DL+++YVDL+LIH+P K Sbjct: 61 GVKRAIDEGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFK 120 Query: 121 ---------KGSVGIKPENLLPVDIP--STWKAMEALYDSGKARAIGVSNFSTKKLADLL 169 G N + D+P TWKA+E L +GK ++IGVSNF L DLL Sbjct: 121 FVPIEEKYPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLL 180 Query: 170 ELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWL-KSDVLKNPIL- 227 A + PAV QVE HP +Q KL EF + GV ++AYS G + + L P L Sbjct: 181 RGATIKPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLF 240 Query: 228 -----NMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKEN--FNVFDWSIPDY 277 +A K K+PA+V LRW Q G +V+PKS R+ +N FN FD + D+ Sbjct: 241 AHDTIKAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKEDF 297 >5ZCM-A nrPDB Length = 341 Score = 214 bits (545), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 119/297 (40%), Positives = 173/297 (58%), Gaps = 18/297 (6%) Query: 9 KLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFED 68 KLN+G + P VG G W+ D V A+K+GYR D A YGN KEIG + + ++ Sbjct: 25 KLNSGYEMPLVGFGCWKVDNATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGINRALDE 84 Query: 69 RVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIK- 127 +V R++LFITSKLW + HDP++V AL + L D++L+Y+DL+LIH+P K K Sbjct: 85 GLVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAFKFVPFEEKY 144 Query: 128 --------PENLLPVDIP--STWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPA 177 +N D+P TWKAME L GKA++IG+SNFS + DLL A + PA Sbjct: 145 PPAFYCGDGDNFHYEDVPLLETWKAMEKLTKGGKAKSIGISNFSAALIYDLLRGAEIKPA 204 Query: 178 VNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLK-SDVLKNPIL------NMV 230 V Q+E HP +Q +L E+ +S+G+ ++AYS G LK S L P L + Sbjct: 205 VLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFLELKHSKALDTPTLFEHKTITSI 264 Query: 231 AEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQ 287 A+K K+PAQV LRW Q +++PKS N R+ +N V D+++ F + ++++Q Sbjct: 265 ADKYKKTPAQVLLRWASQRDIAIIPKSNNPDRLLQNLEVNDFNLSKEDFDEISKLDQ 321 >5JM5-A nrPDB Length = 332 Score = 211 bits (538), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 122/287 (42%), Positives = 173/287 (60%), Gaps = 28/287 (9%) Query: 9 KLNTGAKFPSVGLGTWQASPGL----VGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 KLN G P +G GT+ A P + + A++ G+RHID A +Y NE+++G ++ Sbjct: 9 KLNDGHFMPVLGFGTY-APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67 Query: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSV 124 D VKRED+F TSKLW T H P+ V AL +LK QL+YVDLYLIH P +K G Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG-- 125 Query: 125 GIKPENLLP-----------VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA- 172 E L P VD+ +TW+AME D+G A++IGVSNF+ ++L +L Sbjct: 126 ----EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181 Query: 173 -RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSP-GTTWLKSD---VLKNPIL 227 + P NQVECHP + ++KL +FCKSK + L AYS LGS W+ + +L++P+L Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVL 241 Query: 228 NMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 +A+K ++PA +ALR+ LQ G VL KS NE RI++N VF++ + Sbjct: 242 CALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQL 288 >3O3R-A nrPDB Length = 316 Score = 210 bits (535), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 128/307 (41%), Positives = 178/307 (57%), Gaps = 22/307 (7%) Query: 6 TFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 TF KL T AK P VGLGTW++ PG V +AV AA+ GYRH DCA +Y NE E+G +++ Sbjct: 3 TFVKLRTKAKMPLVGLGTWKSPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEK 62 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 +++ V+REDLFI SKLW T + + EA +TL DL+L+Y+DLYLIHWP ++ G Sbjct: 63 IKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAG--- 119 Query: 126 IKPENLLPVD-----------IPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA-- 172 + LP D W+ ME L D G +A+GVSNF+ ++ LL Sbjct: 120 ---KEFLPKDSQGKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGL 176 Query: 173 RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNM 229 + P NQVECHP Q KL ++C SKG+ + AYSPLGSP + K + VL+ P + Sbjct: 177 KHKPVTNQVECHPYLTQEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVVLEIPKIKE 236 Query: 230 VAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQAR 289 +A K K+ AQV +R+ +Q +V+PKS IKEN VFD+ + + A + + Sbjct: 237 IAAKHKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEEDMAAILSLNRNW 296 Query: 290 LVTGSFL 296 G F+ Sbjct: 297 RACGLFV 303 >1FRB-A nrPDB Length = 315 Score = 209 bits (531), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 125/291 (42%), Positives = 175/291 (60%), Gaps = 22/291 (7%) Query: 6 TFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 TF +L+T AK P VGLGTW++ P V +AV AA+ GYRHIDCA Y NE E+G +++ Sbjct: 2 TFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEK 61 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 +++ V+REDLFI SKLW T + + + EA +TL DL+L+Y+DLYLIHWP ++ G Sbjct: 62 IKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPG--- 118 Query: 126 IKPENLLPVD-----------IPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA-- 172 + L P D W+ ME L D G +A+GVSNF+ ++ LL Sbjct: 119 ---KELFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGL 175 Query: 173 RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNM 229 + P NQVECHP Q KL ++C SKG+ ++AYSPLGSP K + +L++P + Sbjct: 176 KHKPVTNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKE 235 Query: 230 VAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFA 280 +A K K+ AQV +R+ +Q V+PKS RI+EN VFD+ + D A Sbjct: 236 IAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMA 286 >3G1R-A nrPDB Length = 346 Score = 206 bits (524), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 115/280 (41%), Positives = 171/280 (61%), Gaps = 15/280 (5%) Query: 10 LNTGAKFPSVGLGTW---QASP-GLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 L+ G P +GLGT+ +++P G +V A+ GYRHID A IY NE E+G +++ Sbjct: 32 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 91 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKG-SV 124 + V+RED+F KLW T+H P+ V L RTL+ LQL+YVDLY+I P K G + Sbjct: 92 IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI 151 Query: 125 GIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAV 178 + EN ++ +TW+AMEA D+G +++GVSNF+ ++L +L + P Sbjct: 152 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVS 211 Query: 179 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLG-SPGTTWLKSD---VLKNPILNMVAEKL 234 NQVECHP + Q KL +FC+ + ++AYSPLG S W+ +LK+ +LN + ++ Sbjct: 212 NQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRY 271 Query: 235 GKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 K+ AQ+ LR+ +Q G V+PKS N RIKENF +FD+S+ Sbjct: 272 NKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSL 311 >1VP5-A nrPDB Length = 298 Score = 204 bits (519), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 105/289 (36%), Positives = 161/289 (55%), Gaps = 24/289 (8%) Query: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69 LN G + P +G G +Q P + V A+K+GYR ID A Y NE+ +G +K+ ++ Sbjct: 20 LNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKRAIDEG 79 Query: 70 VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129 +V+RE+LF+T+KLW +D + +A ++LK LQLEY+DLYLIH P Sbjct: 80 IVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG----------- 128 Query: 130 NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQ 189 D+ WKAME +Y G RAIGVSNF +L DL+ + PAVNQ+E HP +++ Sbjct: 129 -----DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIEIHPFYQR 183 Query: 190 TKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQM 249 + EF ++ + A+ P + ++ +N +L +AEK GK+ AQV LRW Q Sbjct: 184 QEEIEFMRNYNIQPEAWGPFAEG-----RKNIFQNGVLRSIAEKYGKTVAQVILRWLTQK 238 Query: 250 GHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVH 298 G +PK+ R+KEN ++FD+ + K A +++ + +F H Sbjct: 239 GIVAIPKTVRRERMKENISIFDFELTQEDMEKIATLDEGQ---SAFFSH 284 >1VBJ-A nrPDB Length = 281 Score = 203 bits (516), Expect = 9e-53, Method: Compositional matrix adjust. Identities = 112/268 (41%), Positives = 150/268 (55%), Gaps = 27/268 (10%) Query: 8 FKLNTGAKFPSVGLGTWQASPGLVGD-AVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLF 66 KL+ G P +G G W+ G + A A+K GYRHID A IY NE+ G + Sbjct: 12 LKLSNGVMMPVLGFGMWKLQDGNEAETATMWAIKSGYRHIDTAAIYKNEESAGRAIASC- 70 Query: 67 EDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGI 126 V RE+LF+T+KLW +D + A +++K L LEYVDLYLIHWP + K Sbjct: 71 ---GVPREELFVTTKLWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWPGKDK------ 121 Query: 127 KPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPS 186 TWKA E LY K RAIGVSNF + +LL+ +V P VNQ+E HP Sbjct: 122 ---------FIDTWKAFEKLYADKKVRAIGVSNFHEHHIEELLKHCKVAPMVNQIELHPL 172 Query: 187 WRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWG 246 Q L E+CKSK + ++A+SPLG + ++++ L + K GK+ AQV LRW Sbjct: 173 LNQKALCEYCKSKNIAVTAWSPLG-------QGHLVEDARLKAIGGKYGKTAAQVMLRWE 225 Query: 247 LQMGHSVLPKSTNEGRIKENFNVFDWSI 274 +Q G +PKS NE RIKEN N+FD+ + Sbjct: 226 IQAGVITIPKSGNEARIKENGNIFDFEL 253 >3KRB-A nrPDB Length = 334 Score = 202 bits (513), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 114/280 (40%), Positives = 162/280 (57%), Gaps = 21/280 (7%) Query: 17 PSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDRV--VKRE 74 P +G GTWQA P V AV A+ GYRHIDCA +Y NE+ IG K+F+D +KRE Sbjct: 26 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 85 Query: 75 DLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG-IKPEN--- 130 D++ITSKLW +H P+ V E +T+ DLQ++Y+DL+L+HWP + VG + P++ Sbjct: 86 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 145 Query: 131 ---LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSW 187 L V + TW+AME L + G + IGVSN++ LADLL A++ P VNQ+E HP Sbjct: 146 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWH 205 Query: 188 RQTKLQEFCKSKGVHLSAYSPLG-------SPGTTWLKSDVLKNPILNMVAEKLGKSPAQ 240 +FC G+ ++AYSP+G P T K+ +L+ L +A+ G SP Sbjct: 206 PNDATVKFCLDNGIGVTAYSPMGGSYADPRDPSGT-QKNVILECKTLKAIADAKGTSPHC 264 Query: 241 VALRWGLQ----MGHSVLPKSTNEGRIKENFNVFDWSIPD 276 VAL W ++ +SV+PKS RI+ NF + + D Sbjct: 265 VALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSD 304 >4F40-A nrPDB Length = 288 Score = 199 bits (507), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 112/266 (42%), Positives = 153/266 (57%), Gaps = 19/266 (7%) Query: 10 LNTGAKFPSVGLGTWQASPGLVGD-AVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFED 68 L+ G K P GLG WQ+ G V + AV A+ GYRHID A IY NE+ +GA L+ Sbjct: 15 LSNGVKMPQFGLGVWQSPAGEVTENAVKWALCAGYRHIDTAAIYKNEESVGAGLRA---- 70 Query: 69 RVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKP 128 V RED+FIT+KLW T+ + A + + L ++Y+DLYLIHWP +G + Sbjct: 71 SGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP----RGKDILSK 126 Query: 129 ENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWR 188 E +D +W+A E LY K RAIGVSNF L D+L + V P VNQVE HP Sbjct: 127 EGKKYLD---SWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLNN 183 Query: 189 QTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQ 248 Q L+ FC +K + + A+SPLG + +L NPIL+ + K K+ AQV LRW +Q Sbjct: 184 QADLRAFCDAKQIKVEAWSPLG-------QGKLLSNPILSAIGAKYNKTAAQVILRWNIQ 236 Query: 249 MGHSVLPKSTNEGRIKENFNVFDWSI 274 +PKS + RI+EN ++FD+ + Sbjct: 237 KNLITIPKSVHRERIEENADIFDFEL 262 >1AFS-A nrPDB Length = 323 Score = 198 bits (504), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 118/280 (42%), Positives = 163/280 (58%), Gaps = 16/280 (5%) Query: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKI----GYRHIDCAQIYGNEKEIGAVLKKL 65 LN G P +G GT + D V A KI G+RH D A +Y E+E+G ++ Sbjct: 10 LNDGNFIPVLGFGT-TVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSK 68 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 ED VKRED+F TSKLW T H P+ V L +TLK QL+YVDLY+IH+P ++ G + Sbjct: 69 IEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQPGDIF 128 Query: 126 IKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLEL--ARVPPAV 178 + VDI TW+AME D+G A++IGVSNF+ ++L +L + P Sbjct: 129 FPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPVC 188 Query: 179 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSP-GTTWL--KSDV-LKNPILNMVAEKL 234 NQVECH Q+K+ ++CKSK + L +Y LGS TW+ KS V L +P+L +A+K Sbjct: 189 NQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPVLCAIAKKY 248 Query: 235 GKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 ++PA VALR+ LQ G L +S N RIKE VF++ + Sbjct: 249 KQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQL 288 >5UXF-A nrPDB Length = 342 Score = 195 bits (496), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 121/321 (37%), Positives = 181/321 (56%), Gaps = 19/321 (5%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQ-----ASPGLVGDAVAAAVKIGYRHIDCAQIYGNE 55 M++ KLN G P++G GT++ S L +A A+ +GYRH+D A Y E Sbjct: 20 MSSKQHCVKLNDGHLIPALGFGTYKPKEVPKSKSL--EAACLALDVGYRHVDTAYAYQVE 77 Query: 56 KEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHW 115 +EIG ++ VVKREDLF+T+KLWCT P+ V AL ++LK LQL+YVDLY++H+ Sbjct: 78 EEIGQAIQSAIAAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHY 137 Query: 116 PARIKKGS----VGIKPENLL-PVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLE 170 P +K G V + ++LL VD TW+ +E D+G ++IGVSNF+ ++L +L Sbjct: 138 PVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILN 197 Query: 171 LA--RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPG-TTWLKSD---VLKN 224 + P NQVECH Q KL ++C+SK + L AY LG+ W+ + +L + Sbjct: 198 KPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLND 257 Query: 225 PILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI-PDYMFAKFA 283 P+L VA+K +SPA +ALR+ +Q G L +S E ++EN VF + + P+ M Sbjct: 258 PVLCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDG 317 Query: 284 EIEQARLVTGSFLVHETLSPY 304 + R + FLV P+ Sbjct: 318 LNKNFRYLPAEFLVDHPEYPF 338 >2HE8-A nrPDB Length = 323 Score = 195 bits (496), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 108/279 (38%), Positives = 155/279 (55%), Gaps = 14/279 (5%) Query: 10 LNTGAKFPSVGLGT---WQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLF 66 LN G P +G GT + + A+ G+ H D A +Y E +G ++ Sbjct: 10 LNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRSKI 69 Query: 67 EDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGI 126 D V+RED+F TSK+WCT P+ V +L R+L+ LQ +YVDLYLIH+P +K G Sbjct: 70 ADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGEENF 129 Query: 127 KPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAVN 179 + VD+ +TW+AME D+G ++IGVSNF+ ++L +L + P N Sbjct: 130 PVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCN 189 Query: 180 QVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGT-TWLKSD---VLKNPILNMVAEKLG 235 QVECHP Q KL +FCKSK + L AY LG+ W+ + +L P+L +A+K Sbjct: 190 QVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMAKKYN 249 Query: 236 KSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 ++PA +ALR+ LQ G VL S E RIKEN VF++ + Sbjct: 250 RTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQL 288 >3D3F-A nrPDB Length = 275 Score = 187 bits (476), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 115/267 (43%), Positives = 157/267 (58%), Gaps = 27/267 (10%) Query: 9 KLNTGAKFPSVGLGTWQASPG-LVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFE 67 KL+ G + P GLG ++ G ++V AA+K GYR ID A IY NE+ +G +K Sbjct: 9 KLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIK---- 64 Query: 68 DRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIK 127 + V RE+LFITSK+W D + A ++L+ LQL+Y+DLYLIHWP + K Sbjct: 65 ESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK------- 117 Query: 128 PENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSW 187 TW+A+E LY GK RAIGVSNF L +LL+ A + P VNQVE HP Sbjct: 118 --------YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRL 169 Query: 188 RQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGL 247 Q +L+++CK +G+ L A+SPL ++ +L N +L +AEK KS AQV LRW L Sbjct: 170 TQKELRDYCKGQGIQLEAWSPL-------MQGQLLDNEVLTQIAEKHNKSVAQVILRWDL 222 Query: 248 QMGHSVLPKSTNEGRIKENFNVFDWSI 274 Q G +PKS E RI EN ++FD+ + Sbjct: 223 QHGVVTIPKSIKEHRIIENADIFDFEL 249 >4MHB-A nrPDB Length = 297 Score = 186 bits (473), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 108/297 (36%), Positives = 156/297 (52%), Gaps = 29/297 (9%) Query: 3 NAITFFKLNTGAKFPSVGLGTWQ-ASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAV 61 N + KLN G P +G G +Q + AV A++ GYR ID A Y NE ++G Sbjct: 13 NVMQTVKLNNGIAMPLLGFGVFQMTNTAECERAVIDAIETGYRLIDTAASYQNETQVGNA 72 Query: 62 LKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK 121 LK + R++LFIT+KLW D + R+L LQL+YVDLYLIH P Sbjct: 73 LKL----SGIARDELFITTKLWLQDTYYEGAKAQFERSLNRLQLDYVDLYLIHQPYG--- 125 Query: 122 GSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQV 181 D+ W+AME L+ +GK RAIGVSNF +LADL+ ++ PAVNQ+ Sbjct: 126 -------------DVHGAWRAMEELHQAGKIRAIGVSNFHPDRLADLMAFNKIIPAVNQI 172 Query: 182 ECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQV 241 E +P +Q + +S+G+ A++P ++ + +NP+L + EK GKS QV Sbjct: 173 EVNPFNQQLHAVPWMQSRGIQPEAWAPFAEG-----RNGLFQNPVLTAIGEKYGKSVGQV 227 Query: 242 ALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVH 298 LRW Q G L KS +GR++EN N+ D+ + + A ++ A T +F H Sbjct: 228 VLRWIFQRGIVSLAKSVRKGRMEENINILDFELSAEDMLQIAALDTA---TSAFFSH 281 >1MZR-A nrPDB Length = 296 Score = 185 bits (470), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 106/284 (37%), Positives = 152/284 (53%), Gaps = 24/284 (8%) Query: 6 TFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 T KL G P +GLG WQAS V A+ A+++GYR ID A Y NE+ +G LK Sbjct: 26 TVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALK-- 83 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 + V RE+LFIT+KLW DH + EAL +LK LQL+Y+DLYL+HWP V Sbjct: 84 --NASVNREELFITTKLWNDDH--KRPREALLDSLKKLQLDYIDLYLMHWPVPAIDHYV- 138 Query: 126 IKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHP 185 WK M L G ++IGV NF L L++ V P +NQ+E HP Sbjct: 139 ------------EAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQIELHP 186 Query: 186 SWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRW 245 +Q +L + + + ++SPL G V+++ +A+K GK+PAQ+ +RW Sbjct: 187 LMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRD-----LADKYGKTPAQIVIRW 241 Query: 246 GLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQAR 289 L G V+PKS RI ENF+V+D+ + + A+++Q + Sbjct: 242 HLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGK 285 >3WCZ-A nrPDB Length = 308 Score = 181 bits (458), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 109/296 (36%), Positives = 160/296 (54%), Gaps = 18/296 (6%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQA------SPGLVGDAVAAAVKIGYRHIDCAQIYGN 54 MA +LN G P V LGT + S V AV A++ GYRHID A +Y + Sbjct: 1 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 60 Query: 55 EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIH 114 E+++G + + + +V RE+LF+T+KLW H V AL +LK L L+Y+DLYLIH Sbjct: 61 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 120 Query: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174 +P K P+N +D TW+ M+ G AR+IGVSNF+ ++ L+ + + Sbjct: 121 FPIATKPDD---SPDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 174 Query: 175 PPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLG---SPGTTWLKSDVLKNPILNMVA 231 P +NQ+E +P+ Q L C+S G+ + AYSP G S G T +P L +A Sbjct: 175 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 234 Query: 232 EKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQ 287 K KS Q+ LR+ + G +PKSTN+ RI +N ++FD+ + F + A I Q Sbjct: 235 NKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQL---TFEEVAAINQ 287 >4IJC-A nrPDB Length = 344 Score = 178 bits (451), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 113/276 (40%), Positives = 152/276 (55%), Gaps = 26/276 (9%) Query: 7 FFKLNTGAKFPSVGLGTWQASPGL--VGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 +F LN G + P++GLGT L AV AA+K GYRHID A Y E +G +K+ Sbjct: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 Query: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK--G 122 L ED +KREDLFIT+K+W D +V +LN +LK L LEYVDL L HWP +K Sbjct: 84 LLEDGSIKREDLFITTKVWPVLWD--EVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 Query: 123 SVGIKPENLLPVDIP------------STWKAMEALY---DSGKARAIGVSNFSTKKLAD 167 GI PVD T+K +E +Y + + RAIGVSNFS + L Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 Query: 168 LLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPIL 227 L++ RV P VNQVE HP Q +L++FC + L+AYSPLGS G LK P++ Sbjct: 202 LIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKI-----PLV 256 Query: 228 NMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRI 263 +AEK + + + + ++ G V+P+S N RI Sbjct: 257 KKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRI 292 >1A80-A nrPDB Length = 277 Score = 169 bits (427), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 99/271 (36%), Positives = 141/271 (52%), Gaps = 22/271 (8%) Query: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69 LN G P +G G ++ P AV A+++GYRHID A IYGNE+ +GA + Sbjct: 7 LNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAAS---- 62 Query: 70 VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129 + R+DLFIT+KLW HD + A+ +L L L+ VDLYL+HWP V Sbjct: 63 GIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAADNYV----- 117 Query: 130 NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQ 189 W+ M L +G R+IGVSN L ++ V PAVNQ+E HP+++Q Sbjct: 118 --------HAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQ 169 Query: 190 TKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQM 249 ++ ++ + V + ++ PLG K D+ + A GK+PAQ LRW LQ Sbjct: 170 REITDWAAAHDVKIESWGPLGQG-----KYDLFGAEPVTAAAAAHGKTPAQAVLRWHLQK 224 Query: 250 GHSVLPKSTNEGRIKENFNVFDWSIPDYMFA 280 G V PKS R++EN +VFD+ + D A Sbjct: 225 GFVVFPKSVRRERLEENLDVFDFDLTDTEIA 255 >3UP8-A nrPDB Length = 298 Score = 167 bits (424), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 94/278 (33%), Positives = 156/278 (56%), Gaps = 30/278 (10%) Query: 11 NTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDRV 70 + GA P++G GT++ S V + A+K+G+RH+D AQIYGNE E+G ++K Sbjct: 29 SNGANIPALGFGTFRMSGAEVLRILPQALKLGFRHVDTAQIYGNEAEVGEAIQK----SG 84 Query: 71 VKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPEN 130 + R D+F+T+K+W ++ +++ +L+ L+ ++VDL L+HWP GS Sbjct: 85 IPRADVFLTTKVWVDNYRHDAFIASVDESLRKLRTDHVDLLLLHWP-----GS------- 132 Query: 131 LLPVDIPSTWK--AMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWR 188 D+P + A+ + ++GK R IG+SNF+T ++ + L+ P A NQVE HP Sbjct: 133 ----DVPMAERIGALNEVRNAGKVRHIGISNFNTTQMEEAARLSDAPIATNQVEYHPYLD 188 Query: 189 QTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQ 248 QTK+ + + G+ L++Y + + V +P+L + + GK+ AQVALRW +Q Sbjct: 189 QTKVLQTARRLGMSLTSYYAMAN-------GKVPADPLLTEIGGRHGKTAAQVALRWLVQ 241 Query: 249 MGHS-VLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEI 285 VL K+ E R+KENF +FD+++ A E+ Sbjct: 242 QQDVIVLSKTATEARLKENFAIFDFALTREEMAAVREL 279 >4OTK-A nrPDB Length = 318 Score = 164 bits (416), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 104/273 (38%), Positives = 141/273 (51%), Gaps = 24/273 (8%) Query: 2 ANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAV 61 A A LN P +GLG + S AV+AA++IG R ID A YGNE +G Sbjct: 43 AAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVGRA 102 Query: 62 LKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK 121 + V RE+LF+T+KL D EA +L L L+YVDLYLIHWPA Sbjct: 103 IAA----SGVAREELFVTTKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWPA---- 154 Query: 122 GSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQV 181 P VD W M G AR+IGVSNF+ + + +L++L V PAVNQ+ Sbjct: 155 ------PPVGKYVD---AWGGMIQSRGEGHARSIGVSNFTAENIENLIDLTFVTPAVNQI 205 Query: 182 ECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQV 241 E HP Q +L++ V +Y PL +L NP + +A + K+PAQV Sbjct: 206 ELHPLLNQDELRKANAQHTVVTQSYCPLA-------LGRLLDNPTVTSIASEYVKTPAQV 258 Query: 242 ALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 LRW LQ+G++V+ +S RI NF+VFD+ + Sbjct: 259 LLRWNLQLGNAVVVRSARPERIASNFDVFDFEL 291 >3WG6-A nrPDB Length = 307 Score = 137 bits (346), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 100/293 (34%), Positives = 149/293 (50%), Gaps = 36/293 (12%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQA---------SPGLVGDAVAAAVKIGYRHIDCAQI 51 M+ A FKL+ G K P+V GT L+G + A++ G+RHID A+I Sbjct: 4 MSLAGKEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIG-TLELALRSGFRHIDGAEI 62 Query: 52 YGNEKEIGAVLKKLFEDRVVKREDLFITSKLWCTDH-------DPQDVPEALNRTLKDLQ 104 YG KEIG LK + + R+D+FIT K +H Q+ AL L+DL Sbjct: 63 YGTNKEIGIALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLG 118 Query: 105 LEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKK 164 LEYVDLYLIH+P I + S G D+ W+ +E + G AR IGVSNF+ + Sbjct: 119 LEYVDLYLIHFPY-ISEKSHGF--------DLVEAWRYLERAKNEGLARNIGVSNFTIEN 169 Query: 165 LADLLEL-ARVPPAVNQVECHPSWRQTK--LQEFCKSKGVHLSAYSPLGSPGTTWLKSDV 221 L +L+ P VNQ+E + + E+ + +G+ + AY PLG P T + Sbjct: 170 LKSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLG-PITQGRPGPL 228 Query: 222 LKNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274 K +L+ ++EK ++ Q+ LRW LQ G + ++ E RI + +FD+ + Sbjct: 229 DK--VLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFEL 279 >4H8N-A nrPDB Length = 310 Score = 129 bits (324), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 92/287 (32%), Positives = 151/287 (52%), Gaps = 34/287 (11%) Query: 8 FKLNTGAKFPSVGLGT---WQASPGL------VGDAVAAAVKIGYRHIDCAQIYGNEKEI 58 F+ +G + S+ LGT W+ + + + D + +K+G+RHID A+ Y +KE+ Sbjct: 14 FRTKSGKEI-SIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQKEV 72 Query: 59 GAVLKKLFEDRVVKREDLFITSKL---WCTDHDPQDVP-EALNRTLKDLQLEYVDLYLIH 114 G LK+ V RED+++T+K W + P +++++ L L ++YVDL+LIH Sbjct: 73 GEALKRT----DVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLFLIH 128 Query: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174 P + + G E W+A+ +GK R IG+SN + L L + Sbjct: 129 SPFFTTEQTHGYTLEQ--------AWEALVEAKKAGKVREIGISNAAIPHLEKLFAASPS 180 Query: 175 P---PAVNQVECHPSWR-QTK-LQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNM 229 P P VNQ+E HP + Q+K + FC+ G+ + A+SPL ++++ L L Sbjct: 181 PEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLAPLAR--VETNALAE-TLKR 237 Query: 230 VAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPD 276 +AEK K+ AQV LR+ LQ G + S+ E R+KE+ N+FD+ + D Sbjct: 238 LAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFDFELTD 284 >1PZ1-A nrPDB Length = 333 Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 53/174 (30%), Positives = 88/174 (50%), Gaps = 38/174 (21%) Query: 11 NTGAKFPSVGLGTWQASPGLVG--------DAVAAAVKIGYRHIDCAQIYG---NEKEIG 59 +TG + +GLGTW + G + + AA+ G ID A YG +E+ +G Sbjct: 8 DTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVG 67 Query: 60 AVLKKLFEDRVVKREDLFITSKL---WCTDH-----DPQDVPEALNRTLKDLQLEYVDLY 111 +K+ +KR+ + + +K W + + + E + +LK LQ +Y+DLY Sbjct: 68 KAIKEY-----MKRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLY 122 Query: 112 LIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKL 165 +HWP + L+P++ T + M+ LYD+GK RAIGVSNFS +++ Sbjct: 123 QVHWP------------DPLVPIE--ETAEVMKELYDAGKIRAIGVSNFSIEQM 162 >3EB3-A nrPDB Length = 327 Score = 71.6 bits (174), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 80/309 (25%), Positives = 128/309 (41%), Gaps = 64/309 (20%) Query: 12 TGAKFPSVGLGTWQASPGLVGDAVAA-----AVKIGYRHIDCAQIYGNEKEIGAVLKKLF 66 +G + +GLGTW G + D +A A G D A++Y K VL + Sbjct: 11 SGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGKA-EVVLGNII 69 Query: 67 EDRVVKREDLFITSKLWCTDH-------DPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119 + + +R L IT+K++ + + E L +L+ LQLEYVD+ + Sbjct: 70 KKKGWRRSSLVITTKIFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFAN----- 124 Query: 120 KKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELAR----VP 175 +P+ P++ T +AM + + G A G S +S+ ++ + +AR +P Sbjct: 125 -------RPDPNTPME--ETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIP 175 Query: 176 PAVNQVECHPSWR---QTKLQEFCKSKGVHLSAYSPL-----------GSP--------G 213 P Q E H R + +L E GV +SPL G P G Sbjct: 176 PICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKG 235 Query: 214 TTWLKSDVL---------KNPILNMVAEKLGKSPAQVALRWGLQMG--HSVLPKSTNEGR 262 WLK +L K L +AE+LG + Q+A+ W L+ SVL ++N + Sbjct: 236 YQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQ 295 Query: 263 IKENFNVFD 271 + EN Sbjct: 296 LMENIGAIQ 304 >1LQA-A nrPDB Length = 346 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 70/228 (30%), Positives = 96/228 (42%), Gaps = 40/228 (17%) Query: 18 SVGLGTW----QASPGLVGDAVAAAVKIGYRHIDCAQIYG----------NEKEIGAVLK 63 ++GLGT Q S + AV G ID A++Y E +G L Sbjct: 15 TLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLA 74 Query: 64 KLFEDRVVKREDLFITSKLWCTDH------------DPQDVPEALNRTLKDLQLEYVDLY 111 K RE L I SK+ D +++ EAL+ +LK LQ +Y+DLY Sbjct: 75 KHG-----SREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLY 129 Query: 112 LIHWPARIKK--GSVGIKPENLLP-VDIPSTWKAMEALYDSGKARAIGVSN---FSTKK- 164 +HWP R G +G + P V + T A+ +GK R IGVSN F + Sbjct: 130 QVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRY 189 Query: 165 --LADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLG 210 LAD +L R+ N + L E + +GV L AYS LG Sbjct: 190 LHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLG 237 >1PYF-A nrPDB Length = 312 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 51/172 (29%), Positives = 82/172 (47%), Gaps = 41/172 (23%) Query: 16 FPSVGLGTWQAS-----PGLVGDA----VAAAVKIGYRHIDCAQIYG---NEKEIGAVLK 63 FP +GLGT P L + V A++ G +D A IYG +E+ IG VL+ Sbjct: 14 FP-IGLGTNAVGGHNLYPNLNEETGKELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLR 72 Query: 64 KLFEDRVVKREDLFITSKL--------WCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHW 115 + RED+ I +K + D+ P + ++++ +LK L +Y+DL+ IH+ Sbjct: 73 EF------NREDVVIATKAAHRKQGNDFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHF 126 Query: 116 PARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLAD 167 P+ P D A+ + +GK R+IGVSNFS ++L + Sbjct: 127 ------------PDEHTPKD--EAVNALNEMKKAGKIRSIGVSNFSLEQLKE 164 >3N6Q-A nrPDB Length = 346 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 76/318 (23%), Positives = 145/318 (45%), Gaps = 80/318 (25%) Query: 12 TGAKFPSVGLGTWQASPGLVGD------AVAAAVKIGYRHIDCAQIYG-----NEKEIGA 60 +G + P++ LG W + G V + A +G H D A YG E+ G Sbjct: 21 SGLRLPALSLGLWH-NFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGR 79 Query: 61 VLKKLFEDRVVKREDLFITSK----LW----CTDHDPQDVPEALNRTLKDLQLEYVDLYL 112 +L+ ED R++L I++K +W + + + +L+++LK + LEYVD++ Sbjct: 80 LLR---EDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFY 136 Query: 113 IHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFS---TKKLADLL 169 H R+ + + P++ T A+ SGKA +G+S++S T+K+ +LL Sbjct: 137 SH---RVDENT---------PME--ETASALAHAVQSGKALYVGISSYSPERTQKMVELL 182 Query: 170 ELARVPPAVNQVECHPSWR-------QTKLQEFCKSKGVHLSAYSPL-----------GS 211 ++P ++Q PS+ ++ L + ++ GV A++PL G Sbjct: 183 REWKIPLLIHQ----PSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGI 238 Query: 212 PGTTWL----------------KSDVLKNPILNMVAEKLGKSPAQVALRWGLQMGH--SV 253 P + + ++++ +LN +A++ G+S AQ+AL W L+ SV Sbjct: 239 PQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSV 298 Query: 254 LPKSTNEGRIKENFNVFD 271 L ++ +++EN + Sbjct: 299 LIGASRAEQLEENVQALN 316 >1OG6-A nrPDB Length = 298 Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 69/255 (27%), Positives = 106/255 (41%), Gaps = 39/255 (15%) Query: 21 LGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGN---EKEIGAVLKKLFEDR----VVKR 73 L W S + + + +G +D A IYG E G LK R +V + Sbjct: 24 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSK 83 Query: 74 EDLFITSK------LWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIK 127 + T++ + TD D + ++ ++L +L +++DL LIH + Sbjct: 84 CGIATTAREENVIGHYITDRD--HIIKSAEQSLINLATDHLDLLLIH------------R 129 Query: 128 PENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSW 187 P+ L+ D A + L+ SGK R GVSNF+ + A L A NQVE P Sbjct: 130 PDPLMDAD--EVADAFKHLHQSGKVRHFGVSNFTPAQFALLQSRLPFTLATNQVEISPVH 187 Query: 188 RQTKLQ---EFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPI---LNMVAEKLGK-SPAQ 240 + L + + V A+S LG G D + P+ L +VAE+L S Q Sbjct: 188 QPLLLDGTLDQLQQLRVRPMAWSCLG--GGRLFNDDYFQ-PLRDELAVVAEELNAGSIEQ 244 Query: 241 VALRWGLQMGHSVLP 255 V W L++ LP Sbjct: 245 VVNAWVLRLPSQPLP 259 >4R9O-A nrPDB Length = 301 Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 66/253 (26%), Positives = 107/253 (42%), Gaps = 35/253 (13%) Query: 21 LGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGN---EKEIGAVLK---KLFED-RVVKR 73 L W S + + + +G +D A IYG E G L L E ++V + Sbjct: 27 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALTLAPHLREKLQIVTK 86 Query: 74 EDLFITS----KLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129 + T+ KL D + + + ++LK+L +Y+D+ LIH +P+ Sbjct: 87 CGIATTARAENKLGHYITDRRHIILSAEQSLKNLATDYLDMLLIH------------RPD 134 Query: 130 NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQ 189 L+ D +A + L+ SGK R GVSNF+ + L A NQVE P + Sbjct: 135 PLMDAD--DVAEAFQHLHQSGKVRHFGVSNFTPAQFTLLQSRLPFTLATNQVEISPVHQP 192 Query: 190 TKLQ---EFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPI---LNMVAEKLGKSP-AQVA 242 L + + + A+S LG L +D P+ L+++A++L S QV Sbjct: 193 LLLDGTLDQLQQLRIRPMAWSCLGG---GRLFNDEAYQPLRQELSVIAQELNASSIEQVV 249 Query: 243 LRWGLQMGHSVLP 255 W L++ LP Sbjct: 250 YAWILRLPSQPLP 262 >1GVE-A nrPDB Length = 327 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 46/185 (24%), Positives = 83/185 (44%), Gaps = 22/185 (11%) Query: 34 AVAAAVKIGYRHIDCAQIYGN--EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQD 91 +V A ++ G+ ID A +Y N + I L K + + ++ P D Sbjct: 27 SVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCKVKIATKAAPMFGKTLKPAD 86 Query: 92 VPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGK 151 V L +LK LQ VDL+ +H+ P++ P++ T +A L+ GK Sbjct: 87 VRFQLETSLKRLQCPRVDLFYLHF------------PDHGTPIE--ETLQACHQLHQEGK 132 Query: 152 ARAIGVSNFSTKKLADLLELAR----VPPAVNQVECHPSWRQTKLQEF-C-KSKGVHLSA 205 +G+SN+ + ++A++ L + + P V Q + RQ + + F C + G+ A Sbjct: 133 FVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETELFPCLRHFGLRFYA 192 Query: 206 YSPLG 210 ++PL Sbjct: 193 FNPLA 197 >2BP1-A nrPDB Length = 360 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 20/128 (15%) Query: 89 PQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYD 148 P V L +LK LQ VDL+ +H P++ PV+ T A + L+ Sbjct: 117 PDSVRSQLETSLKRLQCPQVDLFYLH------------APDHGTPVE--ETLHACQRLHQ 162 Query: 149 SGKARAIGVSNFSTKKLADLLELAR----VPPAVNQVECHPSWRQTKLQEF-C-KSKGVH 202 GK +G+SN+++ ++A++ L + + P V Q + + RQ + + F C + G+ Sbjct: 163 EGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLR 222 Query: 203 LSAYSPLG 210 AY+PL Sbjct: 223 FYAYNPLA 230 >2C91-A nrPDB Length = 338 Score = 41.2 bits (95), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 20/128 (15%) Query: 89 PQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYD 148 P + L +LK LQ VDL+ +H P++ PV+ T A L+ Sbjct: 95 PDSIRSQLETSLKRLQCPRVDLFYLH------------APDHSTPVE--ETLCACHQLHQ 140 Query: 149 SGKARAIGVSNFSTKKLADLLELAR----VPPAVNQVECHPSWRQ--TKLQEFCKSKGVH 202 GK +G+SN+++ ++A++ L + + P V Q + + RQ +L + G+ Sbjct: 141 EGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVEAELLPCLRHFGLR 200 Query: 203 LSAYSPLG 210 AY+PL Sbjct: 201 FYAYNPLA 208 >2CLP-A nrPDB Length = 347 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 20/128 (15%) Query: 89 PQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYD 148 P + L +LK LQ VDL+ +H P++ PV+ T +A L+ Sbjct: 104 PDSLRFQLETSLKRLQCPRVDLFYLH------------MPDHSTPVE--ETLRACHQLHQ 149 Query: 149 SGKARAIGVSNFSTKKLADLLELAR----VPPAVNQVECHPSWRQTKLQEF-C-KSKGVH 202 GK +G+SN++ ++A++ L + + P V Q + RQ + + F C + G+ Sbjct: 150 EGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLR 209 Query: 203 LSAYSPLG 210 A++PL Sbjct: 210 FYAFNPLA 217 >2WHY-A nrPDB Length = 311 Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust. Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%) Query: 170 ELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNM 229 E A P A+ +E +P W+ K K V++++ PL GT W K LK Sbjct: 239 ENADKPDALKDLEKNPIWKSLKA---VKEDHVYVNSVDPLAQGGTAWSKVRFLK-----A 290 Query: 230 VAEKLGKSPAQVALR 244 AEKL ++ AL Sbjct: 291 AAEKLTQNKLAAALE 305 >2DLD-A nrPDB Length = 337 Score = 31.2 bits (69), Expect = 0.62, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 9/80 (11%) Query: 101 KDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSG----KARAIG 156 KD+ ++Y D L A++ KG+ G+ ++ + T ++AL D+G R +G Sbjct: 25 KDIDVDYTDKLLTPETAKLAKGADGV----VVYQQLDYTADTLQALADAGVTKMSLRNVG 80 Query: 157 VSNFSTKKLADL-LELARVP 175 V N K +L ++ VP Sbjct: 81 VDNIDMDKAKELGFQITNVP 100 >2D4E-A nrPDB Length = 515 Score = 31.2 bits (69), Expect = 0.62, Method: Compositional matrix adjust. Identities = 42/145 (28%), Positives = 66/145 (45%), Gaps = 25/145 (17%) Query: 108 VDLYLIHWPARIKKGSVGIKPENLLPVDIP---STWKAMEALY--DSGKARAIGVSNFST 162 VD +++ R+ G VGI + P + P STW+ AL ++ + S F+ Sbjct: 150 VDRDWLYYTVRVPAGPVGI----ITPWNAPLMLSTWRIAPALAFGNTVVLKPAEWSPFTA 205 Query: 163 KKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYS--PLGS-PGTTWLKS 219 KLA++L+ A +PP V + +Q F + G L A+ PL + G T Sbjct: 206 TKLAEILKEADLPPGVFNL----------VQGFGEEAGAALVAHPLVPLLTLTGETETGK 255 Query: 220 DVLKNP---ILNMVAEKLGKSPAQV 241 V++N + + E GKSPA V Sbjct: 256 IVMRNAADHLKRLSPELGGKSPALV 280 >4NZZ-A nrPDB Length = 320 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 16/85 (18%) Query: 29 GLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLK--------KLFEDRVVKREDLF--- 77 GL + VK GY D Q Y N E G+VL K+F + ++R+ LF Sbjct: 197 GLRKLVIDPGVKKGYLTADDVQAYMNSWENGSVLSMLSYYRNLKIFTEEDLRRKSLFPLE 256 Query: 78 -----ITSKLWCTDHDPQDVPEALN 97 I ++ + DP +PE L+ Sbjct: 257 EEVLNIPVQIIWGNQDPTFMPENLD 281 >1FP7-A nrPDB Length = 557 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 12/90 (13%) Query: 227 LNMVAEKLGKSPAQVALRW------GLQMGHSVLPKSTNEGRIKENFNV---FDWSIPDY 277 LN++ E K+ A+VAL W GL++ VL T E R NF+V D SI D Sbjct: 392 LNLLYELCAKAGAEVALSWAKGGEGGLELARKVL--QTLESR-PSNFHVLYNLDLSIKDK 448 Query: 278 MFAKFAEIEQARLVTGSFLVHETLSPYKSI 307 + EI A V + + + Y+S+ Sbjct: 449 IAKIATEIYGADGVNYTAEADKAIQRYESL 478 >3GE9-A nrPDB Length = 255 Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust. Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 2/50 (4%) Query: 224 NPILNMVAEKLGKSP-AQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDW 272 N +LN + EKLG P A + + Q +VLP +T E RI + N W Sbjct: 149 NELLNALEEKLGDEPNALLRKKQARQAARAVLPNAT-ESRIVVSGNFRTW 197 >5FX0-A nrPDB Length = 105 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 11/35 (31%), Positives = 22/35 (62%) Query: 274 IPDYMFAKFAEIEQARLVTGSFLVHETLSPYKSIE 308 + +YM K+ + Q ++TGS+ +H + P+ SI+ Sbjct: 55 MKNYMDEKYGRVWQCVILTGSYWMHFSHEPFLSIQ 89 >5FWZ-A nrPDB Length = 98 Score = 28.1 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 22/35 (62%) Query: 274 IPDYMFAKFAEIEQARLVTGSFLVHETLSPYKSIE 308 + +YM K+ + Q ++TGS+ +H + P+ SI+ Sbjct: 48 MKNYMDEKYGRVWQCVILTGSYWMHFSHEPFLSIQ 82 >4Q0M-A nrPDB Length = 327 Score = 28.1 bits (61), Expect = 5.8, Method: Compositional matrix adjust. Identities = 12/19 (63%), Positives = 14/19 (73%) Query: 28 PGLVGDAVAAAVKIGYRHI 46 PGL GD AAV++GYR I Sbjct: 210 PGLSGDIFRAAVELGYRGI 228 >4GYK-A nrPDB Length = 648 Score = 28.1 bits (61), Expect = 5.9, Method: Compositional matrix adjust. Identities = 13/24 (54%), Positives = 14/24 (58%) Query: 127 KPENLLPVDIPSTWKAMEALYDSG 150 KP+ LPVDIPS K LY G Sbjct: 612 KPKGTLPVDIPSVTKPGNTLYPLG 635 >1J49-A nrPDB Length = 333 Score = 27.7 bits (60), Expect = 6.8, Method: Compositional matrix adjust. Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 9/80 (11%) Query: 101 KDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSG----KARAIG 156 KD+++EY D L + KG+ G+ ++ + + ++AL D+G R +G Sbjct: 25 KDVEVEYTDKLLTPETVALAKGADGV----VVYQQLDYIAETLQALADNGITKMSLRNVG 80 Query: 157 VSNFSTKKLADL-LELARVP 175 V N K +L ++ VP Sbjct: 81 VDNIDMAKAKELGFQITNVP 100 >5JP9-A nrPDB Length = 325 Score = 27.7 bits (60), Expect = 7.3, Method: Compositional matrix adjust. Identities = 9/40 (22%), Positives = 24/40 (60%) Query: 112 LIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGK 151 ++ W R++ + + + L +D+P+ WK + AL+++ + Sbjct: 253 VLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHR 292 >5I4E-A nrPDB Length = 980 Score = 27.3 bits (59), Expect = 8.4, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Query: 118 RIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLE 170 R+ K + P L P +I STW A+E + A A+ + KK+A LL+ Sbjct: 829 RLIKREPFVAPAGLTPNEIDSTWSALEKA-EQEHAEALRIELKRQKKIAVLLQ 880 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3H7U-A nrPDB 504 e-143 5JH1-A nrPDB 464 e-131 3H7R-A nrPDB 457 e-129 4JQA-A nrPDB 440 e-124 1ZUA-X nrPDB 432 e-121 1Q5M-A nrPDB 430 e-121 5JM5-A nrPDB 428 e-120 2FVL-A nrPDB 425 e-119 2ALR-A nrPDB 415 e-116 1HQT-A nrPDB 412 e-116 5UXF-A nrPDB 411 e-115 4GAC-A nrPDB 411 e-115 2HE8-A nrPDB 409 e-115 3RX4-A nrPDB 405 e-113 3G1R-A nrPDB 405 e-113 4HBK-A nrPDB 400 e-112 1AFS-A nrPDB 400 e-112 2BGQ-A nrPDB 399 e-112 1DLA-A nrPDB 398 e-111 1C9W-A nrPDB 397 e-111 1FRB-A nrPDB 391 e-109 3O3R-A nrPDB 390 e-109 5Z6T-A nrPDB 378 e-105 4GIE-A nrPDB 376 e-105 5ZCM-A nrPDB 375 e-104 1K8C-A nrPDB 374 e-104 3WCZ-A nrPDB 370 e-103 1VP5-A nrPDB 368 e-102 1QWK-A nrPDB 366 e-102 4F40-A nrPDB 364 e-101 1VBJ-A nrPDB 361 e-100 1MZR-A nrPDB 350 5e-97 4MHB-A nrPDB 346 1e-95 3KRB-A nrPDB 340 5e-94 3D3F-A nrPDB 332 1e-91 4OTK-A nrPDB 322 2e-88 1A80-A nrPDB 319 1e-87 4IJC-A nrPDB 311 2e-85 3UP8-A nrPDB 299 1e-81 3WG6-A nrPDB 282 1e-76 4H8N-A nrPDB 274 4e-74 3EB3-A nrPDB 204 3e-53 4R9O-A nrPDB 190 9e-49 3N6Q-A nrPDB 182 3e-46 1OG6-A nrPDB 180 5e-46 1LQA-A nrPDB 179 1e-45 1PYF-A nrPDB 175 2e-44 1PZ1-A nrPDB 165 2e-41 1GVE-A nrPDB 151 4e-37 2CLP-A nrPDB 143 1e-34 2C91-A nrPDB 140 7e-34 2BP1-A nrPDB 139 1e-33 Sequences not found previously or not previously below threshold: 4EXA-A nrPDB 73 2e-13 1JPH-A nrPDB 32 0.37 4EHI-A nrPDB 31 0.52 5ZF1-A nrPDB 30 1.5 2WUA-A nrPDB 30 1.7 3Q3N-A nrPDB 30 1.8 5BU6-A nrPDB 29 2.7 3EAG-A nrPDB 29 3.3 1TLU-A nrPDB 29 3.6 1CP2-A nrPDB 28 3.8 4YWJ-A nrPDB 28 3.8 3ZL8-A nrPDB 28 4.4 5OWV-A nrPDB 28 5.2 4A35-A nrPDB 28 5.4 3IWD-A nrPDB 28 5.5 5LNB-B nrPDB 28 7.5 >3H7U-A nrPDB Length = 335 Score = 504 bits (1299), Expect = e-143, Method: Composition-based stats. Identities = 315/315 (100%), Positives = 315/315 (100%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA Sbjct: 21 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 80 Query: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK Sbjct: 81 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 140 Query: 121 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 180 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ Sbjct: 141 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 200 Query: 181 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ 240 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ Sbjct: 201 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ 260 Query: 241 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHET 300 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHET Sbjct: 261 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHET 320 Query: 301 LSPYKSIEELWDGEI 315 LSPYKSIEELWDGEI Sbjct: 321 LSPYKSIEELWDGEI 335 >5JH1-A nrPDB Length = 309 Score = 464 bits (1195), Expect = e-131, Method: Composition-based stats. Identities = 220/311 (70%), Positives = 260/311 (83%), Gaps = 2/311 (0%) Query: 5 ITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 F LNTGAK PSVGLG+WQ+ PG+VG+AV AAVK GYRHIDCA++YGNEKEIG LKK Sbjct: 1 ARHFVLNTGAKIPSVGLGSWQSDPGVVGNAVYAAVKAGYRHIDCARVYGNEKEIGLALKK 60 Query: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSV 124 LFE+ VVKRED+FITSKLW H P+DVPEALN +L DLQLEY+DLYLIHWP R+KKG+ Sbjct: 61 LFEEGVVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQLEYLDLYLIHWPFRVKKGT- 119 Query: 125 GIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECH 184 PEN + D P+TW AME LYD+GKARAIGVSNFS+KKL DLL +ARVPPAV+QVECH Sbjct: 120 NTSPENFVTPDFPATWGAMEKLYDAGKARAIGVSNFSSKKLGDLLAVARVPPAVDQVECH 179 Query: 185 PSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALR 244 P W+QTKL FC+S GVHL+AYSPLGSPGTTW+ +VLK PI+ +AEKLGK+ AQVALR Sbjct: 180 PGWQQTKLHSFCQSTGVHLTAYSPLGSPGTTWMNGNVLKEPIIISIAEKLGKTSAQVALR 239 Query: 245 WGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHETLSPY 304 W +QMGHSVLPKSTNE RIK+N +V+DWSIPD + AKF+EI+QARL+ G+F+V+ S Y Sbjct: 240 WNIQMGHSVLPKSTNEERIKQNLDVYDWSIPDDLLAKFSEIKQARLLRGNFIVN-PESVY 298 Query: 305 KSIEELWDGEI 315 K+ EELWDGE+ Sbjct: 299 KTHEELWDGEL 309 >3H7R-A nrPDB Length = 331 Score = 457 bits (1177), Expect = e-129, Method: Composition-based stats. Identities = 211/315 (66%), Positives = 243/315 (77%), Gaps = 4/315 (1%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 MA I FF+LNTGAK P VGLGT+ +V A+ A+KIGYRHIDCA IYGNEKEIG Sbjct: 21 MAAPIRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGG 76 Query: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 VLKKL D VKRE+LFITSKLW DH P+DVP+AL +TL+DLQ++YVDLYLIHWPA +K Sbjct: 77 VLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK 136 Query: 121 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 180 K S+ PE L DI STWKAMEALYDSGKARAIGVSNFS+KKL DLL +ARV PAVNQ Sbjct: 137 KESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQ 196 Query: 181 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ 240 VECHP W+Q L E CKSKGVHLS YSPLGS ++ VL+NPI+ VAEKLGK+ AQ Sbjct: 197 VECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQ 256 Query: 241 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHET 300 VALRWGLQ GHSVLPKS++ R+KEN +VFDWSIP+ +F KF+ I Q + + HET Sbjct: 257 VALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHET 316 Query: 301 LSPYKSIEELWDGEI 315 YK+IEELWDGEI Sbjct: 317 HGFYKTIEELWDGEI 331 >4JQA-A nrPDB Length = 331 Score = 440 bits (1131), Expect = e-124, Method: Composition-based stats. Identities = 125/319 (39%), Positives = 181/319 (56%), Gaps = 15/319 (4%) Query: 1 MANAITFFKLNTGAKFPSVGLGTW---QASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKE 57 M + KLN G P +G GT+ + +AV A++ G+ HID A +Y NE++ Sbjct: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 58 IGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPA 117 +G ++ D VKRED+F TSKLW H P+ V AL R+LK+LQL+YVDLYLIH+P Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 118 RIKKGSVGIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA 172 +K G I + VD+ +TW+AME D+G A++IGVSNF+ + L +L Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 173 --RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPG-TTWLKSD---VLKNPI 226 + P NQVECHP + Q KL +FCKSK + L AYS LGS W+ + +L++P+ Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240 Query: 227 LNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIE 286 L +A+K ++PA +ALR+ LQ G VL KS NE RI++N VF++ + + Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300 Query: 287 QA-RLVTGSFLVHETLSPY 304 + R +T P+ Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319 >1ZUA-X nrPDB Length = 317 Score = 432 bits (1110), Expect = e-121, Method: Composition-based stats. Identities = 127/313 (40%), Positives = 176/313 (56%), Gaps = 11/313 (3%) Query: 5 ITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 TF +L+T AK P VGLGTW++ G V +AV A+ GYRHIDCA +Y NE E+G +++ Sbjct: 3 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 62 Query: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSV 124 +++ VKREDLFI SKLW T + V +A +TLKDL+L Y+D+YLIHWP K G Sbjct: 63 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 122 Query: 125 GIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPA 177 ++ W+AME L D G +A+GVSNFS ++ LL + P Sbjct: 123 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 182 Query: 178 VNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKL 234 NQVECHP Q KL ++C SKG+ ++AYSPLGSP W K + +L++P + +A K Sbjct: 183 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 242 Query: 235 GKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGS 294 K+ AQV +R+ +Q V+PKS RI EN VFD+ + D A + Sbjct: 243 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 302 Query: 295 FLVHE-TLSPYKS 306 P+ + Sbjct: 303 LQSSHLEDYPFNA 315 >1Q5M-A nrPDB Length = 322 Score = 430 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 129/312 (41%), Positives = 179/312 (57%), Gaps = 15/312 (4%) Query: 8 FKLNTGAKFPSVGLGTW---QASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 L+ G P +G GT+ + +A A+ G+RHID A Y NEKE+G ++ Sbjct: 7 VALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRS 66 Query: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSV 124 D VKRED+F TSKLWCT H P+ V +L +LK+LQL+YVDLY+IH+P +K G Sbjct: 67 KIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGVE 126 Query: 125 GIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPA 177 I + VDI +TW+AME D+G A++IGVSNF+ ++L +L + P Sbjct: 127 IIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 186 Query: 178 VNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTT-WLK---SDVLKNPILNMVAEK 233 NQVECHP Q KL EFCKSKG+ L AYS LGS W+ +L++P++ +A+K Sbjct: 187 CNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAKK 246 Query: 234 LGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQA-RLVT 292 ++PA +ALR+ LQ G VL KS E RIKEN VF++ +P + + R VT Sbjct: 247 HQQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSEDMKVIDSLNRNFRYVT 306 Query: 293 GSFLVHETLSPY 304 F + P+ Sbjct: 307 ADFAIGHPNYPF 318 >5JM5-A nrPDB Length = 332 Score = 428 bits (1102), Expect = e-120, Method: Composition-based stats. Identities = 120/319 (37%), Positives = 175/319 (54%), Gaps = 15/319 (4%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASP---GLVGDAVAAAVKIGYRHIDCAQIYGNEKE 57 M + KLN G P +G GT+ + A++ G+RHID A +Y NE++ Sbjct: 1 MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60 Query: 58 IGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPA 117 +G ++ D VKRED+F TSKLW T H P+ V AL +LK QL+YVDLYLIH P Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 118 RIKKGSVGIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA 172 +K G + VD+ +TW+AME D+G A++IGVSNF+ ++L +L Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 173 --RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSP-GTTWLKSD---VLKNPI 226 + P NQVECHP + ++KL +FCKSK + L AYS LGS W+ + +L++P+ Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240 Query: 227 LNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIE 286 L +A+K ++PA +ALR+ LQ G VL KS NE RI++N VF++ + ++ Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300 Query: 287 QA-RLVTGSFLVHETLSPY 304 + PY Sbjct: 301 RNLHYFNSDSFASHPNYPY 319 >2FVL-A nrPDB Length = 324 Score = 425 bits (1092), Expect = e-119, Method: Composition-based stats. Identities = 124/319 (38%), Positives = 180/319 (56%), Gaps = 15/319 (4%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAV---AAAVKIGYRHIDCAQIYGNEKE 57 M +LN G P +G GT+ AV A++ G+RHID A +Y NE++ Sbjct: 2 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 61 Query: 58 IGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPA 117 +G ++ D VKRED+F TSKLWCT PQ V AL +LK LQL+YVDLYL+H+P Sbjct: 62 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 121 Query: 118 RIKKGSVGIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA 172 +K G + + VD+ +TW+ ME D+G A++IGVSNF+ ++L +L Sbjct: 122 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKP 181 Query: 173 --RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPG-TTWLKSD---VLKNPI 226 + P NQVECHP Q+KL +FCKSK + L A+S LG+ W+ + +L++P+ Sbjct: 182 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 241 Query: 227 LNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIE 286 L +A+K ++PA +ALR+ LQ G VL KS NE RI+EN VF++ + + Sbjct: 242 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 301 Query: 287 QA-RLVTGSFLVHETLSPY 304 + R V FL+ P+ Sbjct: 302 RNYRYVVMDFLMDHPDYPF 320 >2ALR-A nrPDB Length = 324 Score = 415 bits (1066), Expect = e-116, Method: Composition-based stats. Identities = 133/320 (41%), Positives = 185/320 (57%), Gaps = 19/320 (5%) Query: 4 AITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLK 63 A + L+TG K P +GLGTW++ PG V AV A+ +GYRHIDCA IYGNE EIG LK Sbjct: 1 AASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 60 Query: 64 K-LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKG 122 + + + V RE+LF+TSKLW T H P+DV AL +TL DLQLEY+DLYL+HWP ++G Sbjct: 61 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 120 Query: 123 SVGIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPA 177 TWKA+EAL G +A+G+SNF+++++ D+L +A V PA Sbjct: 121 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPA 180 Query: 178 VNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKL 234 V QVECHP Q +L C+++G+ ++AYSPLGS W D +L+ P++ +AEK Sbjct: 181 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKY 240 Query: 235 GKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGS 294 G+SPAQ+ LRW +Q +PKS RI +N VFD++ + + + Sbjct: 241 GRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVP 300 Query: 295 FLV----------HETLSPY 304 L L P+ Sbjct: 301 MLTVDGKRVPRDAGHPLYPF 320 >1HQT-A nrPDB Length = 326 Score = 412 bits (1060), Expect = e-116, Method: Composition-based stats. Identities = 130/320 (40%), Positives = 182/320 (56%), Gaps = 19/320 (5%) Query: 4 AITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLK 63 A + L+TG K P +GLGTW++ PG V A+ A+ +GYRHIDCA I+GNE EIG L+ Sbjct: 3 AASCVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQ 62 Query: 64 KLFEDR-VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKG 122 + V RE+LF+TSKLW T H P+DV AL +TL DLQLEY+DLYL+HWP ++G Sbjct: 63 ETVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 122 Query: 123 SVGIKPE-----NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPA 177 TWKA+EAL G RA+G+SNFS++++ D+L +A V PA Sbjct: 123 DNPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRPA 182 Query: 178 VNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKL 234 V QVECHP Q +L C+++G+ ++AYSPLGS W + +L+ P++ +AEK Sbjct: 183 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEKY 242 Query: 235 GKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGS 294 +SPAQ+ LRW +Q +PKS RI +N VFD++ + + + Sbjct: 243 NRSPAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALNKNLRFIVP 302 Query: 295 FLV----------HETLSPY 304 L L P+ Sbjct: 303 MLTVDGKRVPRDAGHPLYPF 322 >5UXF-A nrPDB Length = 342 Score = 411 bits (1056), Expect = e-115, Method: Composition-based stats. Identities = 115/319 (36%), Positives = 172/319 (53%), Gaps = 15/319 (4%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQ---ASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKE 57 M++ KLN G P++G GT++ +A A+ +GYRH+D A Y E+E Sbjct: 20 MSSKQHCVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEE 79 Query: 58 IGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPA 117 IG ++ VVKREDLF+T+KLWCT P+ V AL ++LK LQL+YVDLY++H+P Sbjct: 80 IGQAIQSAIAAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPV 139 Query: 118 RIKKGSVGIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA 172 +K G L VD TW+ +E D+G ++IGVSNF+ ++L +L Sbjct: 140 PMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKP 199 Query: 173 --RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPG-TTWLKSD---VLKNPI 226 + P NQVECH Q KL ++C+SK + L AY LG+ W+ + +L +P+ Sbjct: 200 GLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPV 259 Query: 227 LNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIE 286 L VA+K +SPA +ALR+ +Q G L +S E ++EN VF + + + Sbjct: 260 LCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLN 319 Query: 287 QA-RLVTGSFLVHETLSPY 304 + R + FLV P+ Sbjct: 320 KNFRYLPAEFLVDHPEYPF 338 >4GAC-A nrPDB Length = 324 Score = 411 bits (1056), Expect = e-115, Method: Composition-based stats. Identities = 129/319 (40%), Positives = 180/319 (56%), Gaps = 19/319 (5%) Query: 5 ITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 + L+TG K P +GLGTW++ PG V A+ A+ GYRHIDCA +YGNE EIG LK+ Sbjct: 2 ASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKE 61 Query: 65 LFEDR-VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGS 123 V RE+LF+TSKLW T H P+DV AL +TL DLQLEY+DLYL+HWP ++G Sbjct: 62 SVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 121 Query: 124 VGIKPE-----NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAV 178 TWKA+E L G +A+G+SNF+++++ D+L +A V PAV Sbjct: 122 NPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAV 181 Query: 179 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLG 235 QVECHP Q +L C ++G+ ++AYSPLGS W D +L+ P++ +AEK G Sbjct: 182 LQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHG 241 Query: 236 KSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSF 295 +SPAQ+ LRW +Q +PKS N RI +N VFD++ + + + Sbjct: 242 RSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIVPM 301 Query: 296 LV----------HETLSPY 304 + L P+ Sbjct: 302 ITVDGKRVPRDAGHPLYPF 320 >2HE8-A nrPDB Length = 323 Score = 409 bits (1051), Expect = e-115, Method: Composition-based stats. Identities = 111/319 (34%), Positives = 164/319 (51%), Gaps = 15/319 (4%) Query: 1 MANAITFFKLNTGAKFPSVGLGTW---QASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKE 57 M + LN G P +G GT + + A+ G+ H D A +Y E Sbjct: 1 MNSKCHCVILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDH 60 Query: 58 IGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPA 117 +G ++ D V+RED+F TSK+WCT P+ V +L R+L+ LQ +YVDLYLIH+P Sbjct: 61 VGEAIRSKIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPM 120 Query: 118 RIKKGSVGIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA 172 +K G + VD+ +TW+AME D+G ++IGVSNF+ ++L +L Sbjct: 121 ALKPGEENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKP 180 Query: 173 --RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGT-TWLKSD---VLKNPI 226 + P NQVECHP Q KL +FCKSK + L AY LG+ W+ + +L P+ Sbjct: 181 GLKYKPVCNQVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPV 240 Query: 227 LNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIE 286 L +A+K ++PA +ALR+ LQ G VL S E RIKEN VF++ + + Sbjct: 241 LGSMAKKYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLN 300 Query: 287 QA-RLVTGSFLVHETLSPY 304 + R + + P+ Sbjct: 301 RNMRYIPAAIFKGHPNWPF 319 >3RX4-A nrPDB Length = 336 Score = 405 bits (1041), Expect = e-113, Method: Composition-based stats. Identities = 134/320 (41%), Positives = 188/320 (58%), Gaps = 13/320 (4%) Query: 2 ANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAV 61 ++ + LN GAK P +GLGTW++ PG V +AV A+ +GYRHIDCA +Y NE E+G Sbjct: 19 SHMASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVA 78 Query: 62 LKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK 121 +++ ++VVKRE+LFI SKLWCT H+ V A +TL DL+L+Y+DLYLIHWP K Sbjct: 79 IQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 138 Query: 122 GSVGIKPE---NLLPVD--IPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RV 174 G + N++P D I TW AME L D G +AIG+SNF+ ++ +L + Sbjct: 139 GKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY 198 Query: 175 PPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVA 231 PAVNQ+ECHP Q KL ++C+SKG+ ++AYSPLGSP W K + +L++P + +A Sbjct: 199 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIA 258 Query: 232 EKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLV 291 K K+ AQV +R+ +Q V+PKS RI ENF VFD+ + + V Sbjct: 259 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 318 Query: 292 TGSF-LVHETLSPYKSIEEL 310 P+ EE Sbjct: 319 CALLSCTSHKDYPF--HEEF 336 >3G1R-A nrPDB Length = 346 Score = 405 bits (1041), Expect = e-113, Method: Composition-based stats. Identities = 115/320 (35%), Positives = 174/320 (54%), Gaps = 16/320 (5%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQ----ASPGLVGDAVAAAVKIGYRHIDCAQIYGNEK 56 ++ A L+ G P +GLGT+ G +V A+ GYRHID A IY NE Sbjct: 23 LSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEH 82 Query: 57 EIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWP 116 E+G +++ + V+RED+F KLW T+H P+ V L RTL+ LQL+YVDLY+I P Sbjct: 83 EVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVP 142 Query: 117 ARIKKGSVGIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLEL 171 K G + ++ +TW+AMEA D+G +++GVSNF+ ++L +L Sbjct: 143 MAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK 202 Query: 172 A--RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTT-WLK---SDVLKNP 225 + P NQVECHP + Q KL +FC+ + ++AYSPLG+ W+ +LK+ Sbjct: 203 PGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDA 262 Query: 226 ILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEI 285 +LN + ++ K+ AQ+ LR+ +Q G V+PKS N RIKENF +FD+S+ + + Sbjct: 263 LLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEAL 322 Query: 286 EQA-RLVTGSFLVHETLSPY 304 + R V P+ Sbjct: 323 NKNVRFVELLMWRDHPEYPF 342 >4HBK-A nrPDB Length = 344 Score = 400 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 127/304 (41%), Positives = 180/304 (59%), Gaps = 6/304 (1%) Query: 8 FKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFE 67 K+N G P +GLGTW + PG VG AV A++IGYRH+DCA +Y NE EIG L+ Sbjct: 38 LKMNNGRSIPVIGLGTWNSPPGEVGAAVKKALEIGYRHLDCAYVYRNEAEIGEALENALN 97 Query: 68 DRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIK 127 +KRED+FITSKLW T P+ V +A TLK+L+L Y+DLYLIHWP +K G Sbjct: 98 SLRLKREDIFITSKLWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPLKHGGDLFP 157 Query: 128 PEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVE 182 ++ L V TWK ME L D G ++IG+SNF+ +++ ++LE R+ PA Q+E Sbjct: 158 TDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEHCRIKPANLQIE 217 Query: 183 CHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVA 242 H ++ KL E+ +S G+ ++AY+PLGSP + K ++L P + +A + K+PAQV Sbjct: 218 IHANFPNIKLVEYAQSVGLTVTAYAPLGSPAHSPGKVNLLTKPCVLEIAHRHKKTPAQVL 277 Query: 243 LRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKF-AEIEQARLVTGSFLVHETL 301 LR+ LQ V+PKS RI+ENF VFD+ + + + E R T + Sbjct: 278 LRYLLQRKLIVVPKSVTFKRIEENFQVFDFQLSNEEMHELNTESLNERQFTLLQMSGHQE 337 Query: 302 SPYK 305 P+K Sbjct: 338 YPFK 341 >1AFS-A nrPDB Length = 323 Score = 400 bits (1028), Expect = e-112, Method: Composition-based stats. Identities = 116/319 (36%), Positives = 169/319 (52%), Gaps = 15/319 (4%) Query: 1 MANAITFFKLNTGAKFPSVGLGTW---QASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKE 57 M + LN G P +G GT + + V A A+ G+RH D A +Y E+E Sbjct: 1 MDSISLRVALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEE 60 Query: 58 IGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPA 117 +G ++ ED VKRED+F TSKLW T H P+ V L +TLK QL+YVDLY+IH+P Sbjct: 61 VGQAIRSKIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPM 120 Query: 118 RIKKGSVGIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA 172 ++ G + + VDI TW+AME D+G A++IGVSNF+ ++L +L Sbjct: 121 ALQPGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKP 180 Query: 173 --RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSP-GTTWLKSD---VLKNPI 226 + P NQVECH Q+K+ ++CKSK + L +Y LGS TW+ +L +P+ Sbjct: 181 GLKYKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPV 240 Query: 227 LNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIE 286 L +A+K ++PA VALR+ LQ G L +S N RIKE VF++ + + Sbjct: 241 LCAIAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKALDGLN 300 Query: 287 QA-RLVTGSFLVHETLSPY 304 + R + P+ Sbjct: 301 RNFRYNNAKYFDDHPNHPF 319 >2BGQ-A nrPDB Length = 344 Score = 399 bits (1026), Expect = e-112, Method: Composition-based stats. Identities = 138/310 (44%), Positives = 190/310 (61%), Gaps = 9/310 (2%) Query: 8 FKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFE 67 F L +G P+VGLGTW+A A + GYRH+D A YG EKE+G LK Sbjct: 40 FVLKSGHAMPAVGLGTWRAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAM- 98 Query: 68 DRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIK 127 + + R+DLF+TSK+WCT+ P+ V AL TLKDLQL+Y+DLY IHWP R+K G+ Sbjct: 99 EAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAHMPP 158 Query: 128 P-ENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPS 186 +L D+ WK ME L G + IGV N++ KL LL A++PPAV Q+E HP Sbjct: 159 EAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHPG 218 Query: 187 WRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWG 246 W+ K+ E CK G+H++AYSPLGS + ++ +P++ VA KL K+P QV ++W Sbjct: 219 WKNDKIFEACKKHGIHITAYSPLGSS-----EKNLAHDPVVEKVANKLNKTPGQVLIKWA 273 Query: 247 LQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEI-EQARLVTG-SFLVHETLSPY 304 LQ G SV+PKS+ + RIKEN VF W IP+ F I ++ R++TG V++T PY Sbjct: 274 LQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRVLTGEELFVNKTHGPY 333 Query: 305 KSIEELWDGE 314 +S ++WD E Sbjct: 334 RSARDVWDHE 343 >1DLA-A nrPDB Length = 314 Score = 398 bits (1024), Expect = e-111, Method: Composition-based stats. Identities = 136/313 (43%), Positives = 181/313 (57%), Gaps = 13/313 (4%) Query: 8 FKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFE 67 L TGAK P +GLGTW++ PG V +AV A+ +GYRHIDCA +Y NE E+G L++ + Sbjct: 3 LVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKLQ 62 Query: 68 DRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIK 127 +VVKREDLFI SKLWCTDH+ V A TL+DL+L+Y+DLYLIHWP K G Sbjct: 63 GQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDPFP 122 Query: 128 PE-----NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAVNQ 180 + D TW+AME L D G +AIGVSNF+ ++ +L + PAVNQ Sbjct: 123 LDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQ 182 Query: 181 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLGKS 237 +E HP Q KL E+CKSKG+ ++AYSPLGSP W K + +L++P + +A K K+ Sbjct: 183 IEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKT 242 Query: 238 PAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSF-L 296 AQV +R+ +Q V+PKS RI ENF VFD+ + + V Sbjct: 243 TAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWRVCALMSC 302 Query: 297 VHETLSPYKSIEE 309 P+ EE Sbjct: 303 ASHKDYPF--HEE 313 >1C9W-A nrPDB Length = 315 Score = 397 bits (1019), Expect = e-111, Method: Composition-based stats. Identities = 128/310 (41%), Positives = 180/310 (58%), Gaps = 11/310 (3%) Query: 6 TFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 TF +L+T AK P VGLGTWQ+ PG V +AV A+ GYRHIDCA Y NE E+G +++ Sbjct: 2 TFVELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEK 61 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 +++ V+REDLFI SKLW T + + + EA +TL DL+L+Y+DLYLIHWP ++ G Sbjct: 62 IKEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKEL 121 Query: 126 IKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAV 178 ++ + W+ ME L D G +A+GVSNF+ ++ +L + P Sbjct: 122 FPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPVT 181 Query: 179 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLG 235 NQVECHP Q KL E+C SKG+ ++AYSPLGSP W K + +L++P + +A K Sbjct: 182 NQVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKHK 241 Query: 236 KSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGS- 294 K+ AQV +R+ +Q V+PKS RI ENF VFD+ + D A + Sbjct: 242 KTSAQVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMATILGFNRNWRACLLP 301 Query: 295 FLVHETLSPY 304 V+ PY Sbjct: 302 ETVNMEEYPY 311 >1FRB-A nrPDB Length = 315 Score = 391 bits (1006), Expect = e-109, Method: Composition-based stats. Identities = 125/311 (40%), Positives = 178/311 (57%), Gaps = 11/311 (3%) Query: 5 ITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 TF +L+T AK P VGLGTW++ P V +AV AA+ GYRHIDCA Y NE E+G +++ Sbjct: 1 ATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQE 60 Query: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSV 124 +++ V+REDLFI SKLW T + + + EA +TL DL+L+Y+DLYLIHWP ++ G Sbjct: 61 KIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE 120 Query: 125 GIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPA 177 ++ W+ ME L D G +A+GVSNF+ ++ LL + P Sbjct: 121 LFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPV 180 Query: 178 VNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKL 234 NQVECHP Q KL ++C SKG+ ++AYSPLGSP K + +L++P + +A K Sbjct: 181 TNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKH 240 Query: 235 GKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGS 294 K+ AQV +R+ +Q V+PKS RI+EN VFD+ + D A + Sbjct: 241 EKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACLL 300 Query: 295 -FLVHETLSPY 304 V+ PY Sbjct: 301 PETVNMEEYPY 311 >3O3R-A nrPDB Length = 316 Score = 390 bits (1001), Expect = e-109, Method: Composition-based stats. Identities = 129/316 (40%), Positives = 183/316 (57%), Gaps = 13/316 (4%) Query: 5 ITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 TF KL T AK P VGLGTW++ PG V +AV AA+ GYRH DCA +Y NE E+G +++ Sbjct: 2 TTFVKLRTKAKMPLVGLGTWKSPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQE 61 Query: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSV 124 +++ V+REDLFI SKLW T + + EA +TL DL+L+Y+DLYLIHWP ++ G Sbjct: 62 KIKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGKE 121 Query: 125 GIKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPA 177 + ++ + W+ ME L D G +A+GVSNF+ ++ LL + P Sbjct: 122 FLPKDSQGKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPV 181 Query: 178 VNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKL 234 NQVECHP Q KL ++C SKG+ + AYSPLGSP + K + VL+ P + +A K Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVVLEIPKIKEIAAKH 241 Query: 235 GKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGS 294 K+ AQV +R+ +Q +V+PKS IKEN VFD+ + + A + + G Sbjct: 242 KKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEEDMAAILSLNRNWRACGL 301 Query: 295 FL-VHETLSPYKSIEE 309 F+ E P+ EE Sbjct: 302 FVTSDEEDFPF--HEE 315 >5Z6T-A nrPDB Length = 343 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 126/300 (42%), Positives = 175/300 (58%), Gaps = 18/300 (6%) Query: 5 ITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 + KLN+G P+VG G W+ + + A+K GYR D A+ Y NEK +GA +KK Sbjct: 26 MPSIKLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKK 85 Query: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK---- 120 ++ +VKREDLF+TSKLW H P +V +ALNRTL DLQ++YVDL+LIH+P K Sbjct: 86 AIDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPL 145 Query: 121 -----KGSVGIKPENLLPVDIP--STWKAMEALYDSGKARAIGVSNFSTKKLADLLELAR 173 G K +N D+P TWKA+E L +GK R+IGVSNF L DLL A Sbjct: 146 EEKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLRGAT 205 Query: 174 VPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGS-------PGTTWLKSDVLKNPI 226 + P+V QVE HP +Q +L EF +S+G+ ++AYS G G S + +N Sbjct: 206 IKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENET 265 Query: 227 LNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIE 286 + +A K GKSPAQV LRW Q G +++PKS R+ EN +V + + + FA A+++ Sbjct: 266 IKAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKLD 325 >4GIE-A nrPDB Length = 290 Score = 376 bits (966), Expect = e-105, Method: Composition-based stats. Identities = 117/310 (37%), Positives = 176/310 (56%), Gaps = 29/310 (9%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASPG-LVGDAVAAAVKIGYRHIDCAQIYGNEKEIG 59 M L+ + P +GLG W+A G +AV A++ GYRHID A IY NE+ +G Sbjct: 9 MNCNYNCVTLHNSVRMPQLGLGVWRAQDGAETANAVRWAIEAGYRHIDTAYIYSNERGVG 68 Query: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119 +++ V RE++++T+K+W +D + A R+ + L LEY+DLYLIHWP + Sbjct: 69 QGIRE----SGVPREEVWVTTKVWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWPGKK 124 Query: 120 KKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVN 179 K TWKA+E LY+ K RAIGVSNF L +L + ++ P VN Sbjct: 125 K---------------FVDTWKALEKLYEEKKVRAIGVSNFEPHHLTELFKSCKIRPMVN 169 Query: 180 QVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPA 239 QVE HP ++Q L+EFCK + ++A+SPLGS ++ +LKN +L +A+K KSPA Sbjct: 170 QVELHPLFQQRTLREFCKQHNIAITAWSPLGSGE----EAGILKNHVLGEIAKKHNKSPA 225 Query: 240 QVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHE 299 QV +RW +Q G +PKSTN+GRI+ENFNV+D+ + + + E+ + + + Sbjct: 226 QVVIRWDIQHGIVTIPKSTNKGRIQENFNVWDFKLTEEEMRQIDELNEDKRIGAD----- 280 Query: 300 TLSPYKSIEE 309 + + EE Sbjct: 281 PDNFFPGGEE 290 >5ZCM-A nrPDB Length = 341 Score = 375 bits (964), Expect = e-104, Method: Composition-based stats. Identities = 114/307 (37%), Positives = 174/307 (56%), Gaps = 18/307 (5%) Query: 3 NAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVL 62 + + KLN+G + P VG G W+ D V A+K+GYR D A YGN KEIG + Sbjct: 19 SHMMSIKLNSGYEMPLVGFGCWKVDNATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGI 78 Query: 63 KKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK-- 120 + ++ +V R++LFITSKLW + HDP++V AL + L D++L+Y+DL+LIH+P K Sbjct: 79 NRALDEGLVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAFKFV 138 Query: 121 -------KGSVGIKPENLLPVDIP--STWKAMEALYDSGKARAIGVSNFSTKKLADLLEL 171 +N D+P TWKAME L GKA++IG+SNFS + DLL Sbjct: 139 PFEEKYPPAFYCGDGDNFHYEDVPLLETWKAMEKLTKGGKAKSIGISNFSAALIYDLLRG 198 Query: 172 ARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLK-------SDVLKN 224 A + PAV Q+E HP +Q +L E+ +S+G+ ++AYS G LK + ++ Sbjct: 199 AEIKPAVLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFLELKHSKALDTPTLFEH 258 Query: 225 PILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAE 284 + +A+K K+PAQV LRW Q +++PKS N R+ +N V D+++ F + ++ Sbjct: 259 KTITSIADKYKKTPAQVLLRWASQRDIAIIPKSNNPDRLLQNLEVNDFNLSKEDFDEISK 318 Query: 285 IEQARLV 291 ++Q Sbjct: 319 LDQDLRF 325 >1K8C-A nrPDB Length = 322 Score = 374 bits (960), Expect = e-104, Method: Composition-based stats. Identities = 118/304 (38%), Positives = 174/304 (57%), Gaps = 18/304 (5%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 M+ +I KL++G PS+G G W+ + G+ V A+K GYR D A+ YGNEKE+G Sbjct: 1 MSASIPDIKLSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGD 60 Query: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 +K+ ++ +VKRE++F+TSKLW HDP++V ALN+TL DL+++YVDL+LIH+P K Sbjct: 61 GVKRAIDEGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFK 120 Query: 121 ---------KGSVGIKPENLLPVDIP--STWKAMEALYDSGKARAIGVSNFSTKKLADLL 169 G N + D+P TWKA+E L +GK ++IGVSNF L DLL Sbjct: 121 FVPIEEKYPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLL 180 Query: 170 ELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLK-------SDVL 222 A + PAV QVE HP +Q KL EF + GV ++AYS G + + Sbjct: 181 RGATIKPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLF 240 Query: 223 KNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKF 282 + + +A K K+PA+V LRW Q G +V+PKS R+ +N + + + F + Sbjct: 241 AHDTIKAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKEDFEEI 300 Query: 283 AEIE 286 A+++ Sbjct: 301 AKLD 304 >3WCZ-A nrPDB Length = 308 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 109/313 (34%), Positives = 163/313 (52%), Gaps = 16/313 (5%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQA------SPGLVGDAVAAAVKIGYRHIDCAQIYGN 54 MA +LN G P V LGT + S V AV A++ GYRHID A +Y + Sbjct: 1 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 60 Query: 55 EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIH 114 E+++G + + + +V RE+LF+T+KLW H V AL +LK L L+Y+DLYLIH Sbjct: 61 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 120 Query: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174 +P K P+N +D TW+ M+ G AR+IGVSNF+ ++ L+ + + Sbjct: 121 FPIATKPDD---SPDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 174 Query: 175 PPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLG---SPGTTWLKSDVLKNPILNMVA 231 P +NQ+E +P+ Q L C+S G+ + AYSP G S G T +P L +A Sbjct: 175 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 234 Query: 232 EKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQA-RL 290 K KS Q+ LR+ + G +PKSTN+ RI +N ++FD+ + A + + R+ Sbjct: 235 NKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNHRV 294 Query: 291 VTGSFLVHETLSP 303 + S P Sbjct: 295 IDISDWKDYPNYP 307 >1VP5-A nrPDB Length = 298 Score = 368 bits (946), Expect = e-102, Method: Composition-based stats. Identities = 105/296 (35%), Positives = 161/296 (54%), Gaps = 24/296 (8%) Query: 4 AITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLK 63 + LN G + P +G G +Q P + V A+K+GYR ID A Y NE+ +G +K Sbjct: 14 QVPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIK 73 Query: 64 KLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGS 123 + ++ +V+RE+LF+T+KLW +D + +A ++LK LQLEY+DLYLIH P Sbjct: 74 RAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG----- 128 Query: 124 VGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVEC 183 D+ WKAME +Y G RAIGVSNF +L DL+ + PAVNQ+E Sbjct: 129 -----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIEI 177 Query: 184 HPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVAL 243 HP +++ + EF ++ + A+ P ++ +N +L +AEK GK+ AQV L Sbjct: 178 HPFYQRQEEIEFMRNYNIQPEAWGPFAEGRK-----NIFQNGVLRSIAEKYGKTVAQVIL 232 Query: 244 RWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHE 299 RW Q G +PK+ R+KEN ++FD+ + K A +++ + +F H Sbjct: 233 RWLTQKGIVAIPKTVRRERMKENISIFDFELTQEDMEKIATLDEGQ---SAFFSHR 285 >1QWK-A nrPDB Length = 317 Score = 366 bits (940), Expect = e-102, Method: Composition-based stats. Identities = 125/322 (38%), Positives = 179/322 (55%), Gaps = 18/322 (5%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 M++A KL+ G + P +GLGTWQ+SP V AV AVK GYR ID A +Y NE+ IG Sbjct: 1 MSSATASIKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGT 60 Query: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 +K+L E+ VVKRE+LFIT+K W + P + L +LK LQLEYVDLYL H PA Sbjct: 61 AIKELLEEGVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFN 120 Query: 121 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 180 + PV+ W+ +A+Y +G A+A+GVSN++ +++ L L P +Q Sbjct: 121 DD---MSEHIASPVE--DVWRQFDAVYKAGLAKAVGVSNWNNDQISRALALGLTPVHNSQ 175 Query: 181 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLK------------SDVLKNPILN 228 VE H + Q +FCK + +++Y+ LGSPG L++ + Sbjct: 176 VELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAPSDLQDQNVL 235 Query: 229 MVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQA 288 +AEK K+PAQV LR+ L G ++LPKS E RIKENF VFD+S+ + AK E + + Sbjct: 236 ALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTEEDIAKLEESKNS 295 Query: 289 -RLVTGSFLVHETLSPYKSIEE 309 RL F+ + + + Sbjct: 296 QRLFLQDFMTGHPEDAFAAERK 317 >4F40-A nrPDB Length = 288 Score = 364 bits (935), Expect = e-101, Method: Composition-based stats. Identities = 112/284 (39%), Positives = 154/284 (54%), Gaps = 19/284 (6%) Query: 8 FKLNTGAKFPSVGLGTWQASPGLVGD-AVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLF 66 L+ G K P GLG WQ+ G V + AV A+ GYRHID A IY NE+ +GA L+ Sbjct: 13 VTLSNGVKMPQFGLGVWQSPAGEVTENAVKWALCAGYRHIDTAAIYKNEESVGAGLRA-- 70 Query: 67 EDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGI 126 V RED+FIT+KLW T+ + A + + L ++Y+DLYLIHWP +G + Sbjct: 71 --SGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP----RGKDIL 124 Query: 127 KPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPS 186 E +D +W+A E LY K RAIGVSNF L D+L + V P VNQVE HP Sbjct: 125 SKEGKKYLD---SWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPL 181 Query: 187 WRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWG 246 Q L+ FC +K + + A+SPLG + +L NPIL+ + K K+ AQV LRW Sbjct: 182 NNQADLRAFCDAKQIKVEAWSPLG-------QGKLLSNPILSAIGAKYNKTAAQVILRWN 234 Query: 247 LQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARL 290 +Q +PKS + RI+EN ++FD+ + + Sbjct: 235 IQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSR 278 >1VBJ-A nrPDB Length = 281 Score = 361 bits (928), Expect = e-100, Method: Composition-based stats. Identities = 112/289 (38%), Positives = 150/289 (51%), Gaps = 27/289 (9%) Query: 3 NAITFFKLNTGAKFPSVGLGTWQASPG-LVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAV 61 KL+ G P +G G W+ G A A+K GYRHID A IY NE+ G Sbjct: 7 ALTQSLKLSNGVMMPVLGFGMWKLQDGNEAETATMWAIKSGYRHIDTAAIYKNEESAGRA 66 Query: 62 LKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK 121 + V RE+LF+T+KLW +D + A +++K L LEYVDLYLIHWP + K Sbjct: 67 IASC----GVPREELFVTTKLWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWPGKDK- 121 Query: 122 GSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQV 181 TWKA E LY K RAIGVSNF + +LL+ +V P VNQ+ Sbjct: 122 --------------FIDTWKAFEKLYADKKVRAIGVSNFHEHHIEELLKHCKVAPMVNQI 167 Query: 182 ECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQV 241 E HP Q L E+CKSK + ++A+SPLG + ++++ L + K GK+ AQV Sbjct: 168 ELHPLLNQKALCEYCKSKNIAVTAWSPLG-------QGHLVEDARLKAIGGKYGKTAAQV 220 Query: 242 ALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARL 290 LRW +Q G +PKS NE RIKEN N+FD+ + + Sbjct: 221 MLRWEIQAGVITIPKSGNEARIKENGNIFDFELTAEDIQVIDGMNAGHR 269 >1MZR-A nrPDB Length = 296 Score = 350 bits (898), Expect = 5e-97, Method: Composition-based stats. Identities = 105/286 (36%), Positives = 149/286 (52%), Gaps = 24/286 (8%) Query: 6 TFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 T KL G P +GLG WQAS V A+ A+++GYR ID A Y NE+ +G LK Sbjct: 26 TVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALKNA 85 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 V RE+LFIT+KLW DH EAL +LK LQL+Y+DLYL+HWP Sbjct: 86 ----SVNREELFITTKLWNDDHKR--PREALLDSLKKLQLDYIDLYLMHWPVPAID---- 135 Query: 126 IKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHP 185 WK M L G ++IGV NF L L++ V P +NQ+E HP Sbjct: 136 ---------HYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQIELHP 186 Query: 186 SWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRW 245 +Q +L + + + ++SPL G V ++ +A+K GK+PAQ+ +RW Sbjct: 187 LMQQRQLHAWNATHKIQTESWSPLAQGGKG-----VFDQKVIRDLADKYGKTPAQIVIRW 241 Query: 246 GLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLV 291 L G V+PKS RI ENF+V+D+ + + A+++Q + + Sbjct: 242 HLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKRL 287 >4MHB-A nrPDB Length = 297 Score = 346 bits (887), Expect = 1e-95, Method: Composition-based stats. Identities = 108/299 (36%), Positives = 156/299 (52%), Gaps = 29/299 (9%) Query: 2 ANAITFFKLNTGAKFPSVGLGTWQASP-GLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 N + KLN G P +G G +Q + AV A++ GYR ID A Y NE ++G Sbjct: 12 DNVMQTVKLNNGIAMPLLGFGVFQMTNTAECERAVIDAIETGYRLIDTAASYQNETQVGN 71 Query: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 LK + R++LFIT+KLW D + R+L LQL+YVDLYLIH P Sbjct: 72 ALKL----SGIARDELFITTKLWLQDTYYEGAKAQFERSLNRLQLDYVDLYLIHQPYG-- 125 Query: 121 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 180 D+ W+AME L+ +GK RAIGVSNF +LADL+ ++ PAVNQ Sbjct: 126 --------------DVHGAWRAMEELHQAGKIRAIGVSNFHPDRLADLMAFNKIIPAVNQ 171 Query: 181 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ 240 +E +P +Q + +S+G+ A++P ++ + +NP+L + EK GKS Q Sbjct: 172 IEVNPFNQQLHAVPWMQSRGIQPEAWAPFAEG-----RNGLFQNPVLTAIGEKYGKSVGQ 226 Query: 241 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHE 299 V LRW Q G L KS +GR++EN N+ D+ + + A ++ A T +F H Sbjct: 227 VVLRWIFQRGIVSLAKSVRKGRMEENINILDFELSAEDMLQIAALDTA---TSAFFSHR 282 >3KRB-A nrPDB Length = 334 Score = 340 bits (872), Expect = 5e-94, Method: Composition-based stats. Identities = 112/295 (37%), Positives = 161/295 (54%), Gaps = 19/295 (6%) Query: 17 PSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFED--RVVKRE 74 P +G GTWQA P V AV A+ GYRHIDCA +Y NE+ IG K+F+D +KRE Sbjct: 26 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 85 Query: 75 DLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG-IKPEN--- 130 D++ITSKLW +H P+ V E +T+ DLQ++Y+DL+L+HWP + VG + P++ Sbjct: 86 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 145 Query: 131 ---LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSW 187 L V + TW+AME L + G + IGVSN++ LADLL A++ P VNQ+E HP Sbjct: 146 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWH 205 Query: 188 RQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD------VLKNPILNMVAEKLGKSPAQV 241 +FC G+ ++AYSP+G +L+ L +A+ G SP V Sbjct: 206 PNDATVKFCLDNGIGVTAYSPMGGSYADPRDPSGTQKNVILECKTLKAIADAKGTSPHCV 265 Query: 242 ALRWGLQM----GHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVT 292 AL W ++ +SV+PKS RI+ NF + + D I + + Sbjct: 266 ALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKRIR 320 >3D3F-A nrPDB Length = 275 Score = 332 bits (852), Expect = 1e-91, Method: Composition-based stats. Identities = 117/286 (40%), Positives = 161/286 (56%), Gaps = 27/286 (9%) Query: 7 FFKLNTGAKFPSVGLGTWQASPG-LVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 KL+ G + P GLG ++ G ++V AA+K GYR ID A IY NE+ +G +K+ Sbjct: 7 TVKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIKE- 65 Query: 66 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 125 V RE+LFITSK+W D + A ++L+ LQL+Y+DLYLIHWP + K Sbjct: 66 ---SGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK----- 117 Query: 126 IKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHP 185 TW+A+E LY GK RAIGVSNF L +LL+ A + P VNQVE HP Sbjct: 118 ----------YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHP 167 Query: 186 SWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRW 245 Q +L+++CK +G+ L A+SPL ++ +L N +L +AEK KS AQV LRW Sbjct: 168 RLTQKELRDYCKGQGIQLEAWSPL-------MQGQLLDNEVLTQIAEKHNKSVAQVILRW 220 Query: 246 GLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLV 291 LQ G +PKS E RI EN ++FD+ + K + + V Sbjct: 221 DLQHGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDERV 266 >4OTK-A nrPDB Length = 318 Score = 322 bits (825), Expect = 2e-88, Method: Composition-based stats. Identities = 105/293 (35%), Positives = 143/293 (48%), Gaps = 24/293 (8%) Query: 2 ANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAV 61 A A LN P +GLG + S AV+AA++IG R ID A YGNE +G Sbjct: 43 AAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVGRA 102 Query: 62 LKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK 121 + V RE+LF+T+KL D EA +L L L+YVDLYLIHWPA Sbjct: 103 IAA----SGVAREELFVTTKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWPA---- 154 Query: 122 GSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQV 181 P VD W M G AR+IGVSNF+ + + +L++L V PAVNQ+ Sbjct: 155 ------PPVGKYVD---AWGGMIQSRGEGHARSIGVSNFTAENIENLIDLTFVTPAVNQI 205 Query: 182 ECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQV 241 E HP Q +L++ V +Y PL +L NP + +A + K+PAQV Sbjct: 206 ELHPLLNQDELRKANAQHTVVTQSYCPLAL-------GRLLDNPTVTSIASEYVKTPAQV 258 Query: 242 ALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGS 294 LRW LQ+G++V+ +S RI NF+VFD+ + + V Sbjct: 259 LLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLNDGTRVRED 311 >1A80-A nrPDB Length = 277 Score = 319 bits (817), Expect = 1e-87, Method: Composition-based stats. Identities = 96/282 (34%), Positives = 140/282 (49%), Gaps = 22/282 (7%) Query: 5 ITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 + LN G P +G G ++ P AV A+++GYRHID A IYGNE+ + Sbjct: 2 VPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGV----GA 57 Query: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSV 124 + R+DLFIT+KLW HD + A+ +L L L+ VDLYL+HWP Sbjct: 58 AIAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAADN-- 115 Query: 125 GIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECH 184 W+ M L +G R+IGVSN L ++ V PAVNQ+E H Sbjct: 116 -----------YVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELH 164 Query: 185 PSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALR 244 P+++Q ++ ++ + V + ++ PLG K D+ + A GK+PAQ LR Sbjct: 165 PAYQQREITDWAAAHDVKIESWGPLGQG-----KYDLFGAEPVTAAAAAHGKTPAQAVLR 219 Query: 245 WGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIE 286 W LQ G V PKS R++EN +VFD+ + D A ++ Sbjct: 220 WHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDAMD 261 >4IJC-A nrPDB Length = 344 Score = 311 bits (798), Expect = 2e-85, Method: Composition-based stats. Identities = 115/314 (36%), Positives = 162/314 (51%), Gaps = 33/314 (10%) Query: 7 FFKLNTGAKFPSVGLGTWQASP--GLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64 +F LN G + P++GLGT AV AA+K GYRHID A Y E +G +K+ Sbjct: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 Query: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK--G 122 L ED +KREDLFIT+K+W D +V +LN +LK L LEYVDL L HWP +K Sbjct: 84 LLEDGSIKREDLFITTKVWPVLWD--EVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 Query: 123 SVGIKPENLLPVD------------IPSTWKAMEALY---DSGKARAIGVSNFSTKKLAD 167 GI PVD T+K +E +Y + + RAIGVSNFS + L Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 Query: 168 LLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPIL 227 L++ RV P VNQVE HP Q +L++FC + L+AYSPLGS G LK P++ Sbjct: 202 LIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN-----LKIPLV 256 Query: 228 NMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDW-SIPDYMFAKFAEIE 286 +AEK + + + + ++ G V+P+S N RI + ++ S+ + + Sbjct: 257 KKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSI---EFASLTKDELQELNDFG 313 Query: 287 QARLVTGSFLVHET 300 + V + E Sbjct: 314 EKYPVR---FIDEP 324 >3UP8-A nrPDB Length = 298 Score = 299 bits (766), Expect = 1e-81, Method: Composition-based stats. Identities = 91/278 (32%), Positives = 152/278 (54%), Gaps = 26/278 (9%) Query: 11 NTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDRV 70 + GA P++G GT++ S V + A+K+G+RH+D AQIYGNE E+G ++K Sbjct: 29 SNGANIPALGFGTFRMSGAEVLRILPQALKLGFRHVDTAQIYGNEAEVGEAIQK----SG 84 Query: 71 VKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPEN 130 + R D+F+T+K+W ++ +++ +L+ L+ ++VDL L+HWP Sbjct: 85 IPRADVFLTTKVWVDNYRHDAFIASVDESLRKLRTDHVDLLLLHWP-------------- 130 Query: 131 LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQT 190 V + A+ + ++GK R IG+SNF+T ++ + L+ P A NQVE HP QT Sbjct: 131 GSDVPMAERIGALNEVRNAGKVRHIGISNFNTTQMEEAARLSDAPIATNQVEYHPYLDQT 190 Query: 191 KLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGL-QM 249 K+ + + G+ L++Y + V +P+L + + GK+ AQVALRW + Q Sbjct: 191 KVLQTARRLGMSLTSYYAMA-------NGKVPADPLLTEIGGRHGKTAAQVALRWLVQQQ 243 Query: 250 GHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQ 287 VL K+ E R+KENF +FD+++ A E+ + Sbjct: 244 DVIVLSKTATEARLKENFAIFDFALTREEMAAVRELAR 281 >3WG6-A nrPDB Length = 307 Score = 282 bits (722), Expect = 1e-76, Method: Composition-based stats. Identities = 94/311 (30%), Positives = 149/311 (47%), Gaps = 34/311 (10%) Query: 1 MANAITFFKLNTGAKFPSVGLGTWQAS--------PGLVGDAVAAAVKIGYRHIDCAQIY 52 M+ A FKL+ G K P+V GT + + A++ G+RHID A+IY Sbjct: 4 MSLAGKEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIY 63 Query: 53 GNEKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQ-------DVPEALNRTLKDLQL 105 G KEIG LK + + R+D+FIT K +H + AL L+DL L Sbjct: 64 GTNKEIGIALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGL 119 Query: 106 EYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKL 165 EYVDLYLIH+P E D+ W+ +E + G AR IGVSNF+ + L Sbjct: 120 EYVDLYLIHFPY---------ISEKSHGFDLVEAWRYLERAKNEGLARNIGVSNFTIENL 170 Query: 166 ADLLEL-ARVPPAVNQVECHPSWRQ--TKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVL 222 +L+ P VNQ+E + + E+ + +G+ + AY PLG P T + Sbjct: 171 KSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLG-PITQGRPGPL- 228 Query: 223 KNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKF 282 + +L+ ++EK ++ Q+ LRW LQ G + ++ E RI + +FD+ + + Sbjct: 229 -DKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELDKEDEDQI 287 Query: 283 AEIEQARLVTG 293 ++ + + + Sbjct: 288 TKVGKEKTLRQ 298 >4H8N-A nrPDB Length = 310 Score = 274 bits (700), Expect = 4e-74, Method: Composition-based stats. Identities = 91/307 (29%), Positives = 151/307 (49%), Gaps = 32/307 (10%) Query: 6 TFFKLNTGAKFPS-VGLGT-WQASPG------LVGDAVAAAVKIGYRHIDCAQIYGNEKE 57 F+ +G + +G GT W+ + + D + +K+G+RHID A+ Y +KE Sbjct: 12 KTFRTKSGKEISIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQKE 71 Query: 58 IGAVLKKLFEDRVVKREDLFITSKL---WCTDHDP-QDVPEALNRTLKDLQLEYVDLYLI 113 +G LK+ V RED+++T+K W + + +++++ L L ++YVDL+LI Sbjct: 72 VGEALKRT----DVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLFLI 127 Query: 114 HWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELAR 173 H P + + G E W+A+ +GK R IG+SN + L L + Sbjct: 128 HSPFFTTEQTHGYTLEQ--------AWEALVEAKKAGKVREIGISNAAIPHLEKLFAASP 179 Query: 174 VP---PAVNQVECHPSWRQTK--LQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILN 228 P P VNQ+E HP + + FC+ G+ + A+SPL ++++ L L Sbjct: 180 SPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLAPLAR--VETNALAE-TLK 236 Query: 229 MVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQA 288 +AEK K+ AQV LR+ LQ G + S+ E R+KE+ N+FD+ + D + +I A Sbjct: 237 RLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFDFELTDEEVNEINKIGDA 296 Query: 289 RLVTGSF 295 F Sbjct: 297 NPYRAFF 303 >3EB3-A nrPDB Length = 327 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 78/326 (23%), Positives = 129/326 (39%), Gaps = 66/326 (20%) Query: 11 NTGAKFPSVGLGTWQASPGLVGDAVAA-----AVKIGYRHIDCAQIYGNEKEIGAVLKKL 65 +G + +GLGTW G + D +A A G D A++Y K VL + Sbjct: 10 KSGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGKA-EVVLGNI 68 Query: 66 FEDRVVKREDLFITSKLWCTDH-------DPQDVPEALNRTLKDLQLEYVDLYLIHWPAR 118 + + +R L IT+K++ + + E L +L+ LQLEYVD+ + Sbjct: 69 IKKKGWRRSSLVITTKIFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFAN---- 124 Query: 119 IKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELAR----V 174 +P+ P++ T +AM + + G A G S +S+ ++ + +AR + Sbjct: 125 --------RPDPNTPME--ETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLI 174 Query: 175 PPAVNQVECHPSWR---QTKLQEFCKSKGVHLSAYSPLGSP------------------- 212 PP Q E H R + +L E GV +SPL Sbjct: 175 PPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLK 234 Query: 213 GTTWLKSDVLKN---------PILNMVAEKLGKSPAQVALRWGLQMG--HSVLPKSTNEG 261 G WLK +L L +AE+LG + Q+A+ W L+ SVL ++N Sbjct: 235 GYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAE 294 Query: 262 RIKENFNVFDW--SIPDYMFAKFAEI 285 ++ EN + + + I Sbjct: 295 QLMENIGAIQVLPKLSSSIVHEIDSI 320 >4R9O-A nrPDB Length = 301 Score = 190 bits (482), Expect = 9e-49, Method: Composition-based stats. Identities = 66/284 (23%), Positives = 113/284 (39%), Gaps = 37/284 (13%) Query: 21 LGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGN---EKEIGAVLKKLF----EDRVVKR 73 L W S + + + +G +D A IYG E G L + ++V + Sbjct: 27 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALTLAPHLREKLQIVTK 86 Query: 74 EDLFITS----KLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129 + T+ KL D + + + ++LK+L +Y+D+ LIH P + Sbjct: 87 CGIATTARAENKLGHYITDRRHIILSAEQSLKNLATDYLDMLLIHRPDPL---------- 136 Query: 130 NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQ 189 +D +A + L+ SGK R GVSNF+ + L A NQVE P + Sbjct: 137 ----MDADDVAEAFQHLHQSGKVRHFGVSNFTPAQFTLLQSRLPFTLATNQVEISPVHQP 192 Query: 190 TKL---QEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPI---LNMVAEKLGKSP-AQVA 242 L + + + A+S LG L +D P+ L+++A++L S QV Sbjct: 193 LLLDGTLDQLQQLRIRPMAWSCLG---GGRLFNDEAYQPLRQELSVIAQELNASSIEQVV 249 Query: 243 LRWGLQMGHSVLP--KSTNEGRIKENFNVFDWSIPDYMFAKFAE 284 W L++ LP S R++ S+ + + + Sbjct: 250 YAWILRLPSQPLPIIGSGKIERVRAALEAETLSLTRQQWFRIRK 293 >3N6Q-A nrPDB Length = 346 Score = 182 bits (461), Expect = 3e-46, Method: Composition-based stats. Identities = 70/328 (21%), Positives = 141/328 (42%), Gaps = 71/328 (21%) Query: 11 NTGAKFPSVGLGTWQASP-----GLVGDAVAAAVKIGYRHIDCAQIYG-----NEKEIGA 60 +G + P++ LG W + A +G H D A YG E+ G Sbjct: 20 KSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGR 79 Query: 61 VLKKLFEDRVVKREDLFITSK----LW----CTDHDPQDVPEALNRTLKDLQLEYVDLYL 112 +L++ D R++L I++K +W + + + +L+++LK + LEYVD++ Sbjct: 80 LLRE---DFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFY 136 Query: 113 IHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTK---KLADLL 169 H + + P++ T A+ SGKA +G+S++S + K+ +LL Sbjct: 137 SH------------RVDENTPME--ETASALAHAVQSGKALYVGISSYSPERTQKMVELL 182 Query: 170 ELARVPPAVNQVECHPSWR---QTKLQEFCKSKGVHLSAYSPL-----------GSPGTT 215 ++P ++Q + R ++ L + ++ GV A++PL G P + Sbjct: 183 REWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQDS 242 Query: 216 WL----------------KSDVLKNPILNMVAEKLGKSPAQVALRWGLQMGHS--VLPKS 257 + ++++ +LN +A++ G+S AQ+AL W L+ VL + Sbjct: 243 RMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSVLIGA 302 Query: 258 TNEGRIKENFNVF-DWSIPDYMFAKFAE 284 + +++EN + + A+ + Sbjct: 303 SRAEQLEENVQALNNLTFSTKELAQIDQ 330 >1OG6-A nrPDB Length = 298 Score = 180 bits (458), Expect = 5e-46, Method: Composition-based stats. Identities = 68/284 (23%), Positives = 110/284 (38%), Gaps = 37/284 (13%) Query: 21 LGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGN---EKEIGAVLKKLFEDR----VVKR 73 L W S + + + +G +D A IYG E G LK R +V + Sbjct: 24 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSK 83 Query: 74 EDLFITSK----LWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129 + T++ + D + ++ ++L +L +++DL LIH P + Sbjct: 84 CGIATTAREENVIGHYITDRDHIIKSAEQSLINLATDHLDLLLIHRPDPL---------- 133 Query: 130 NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQ 189 +D A + L+ SGK R GVSNF+ + A L A NQVE P + Sbjct: 134 ----MDADEVADAFKHLHQSGKVRHFGVSNFTPAQFALLQSRLPFTLATNQVEISPVHQP 189 Query: 190 TKL---QEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPI---LNMVAEKLGK-SPAQVA 242 L + + V A+S LG G D + P+ L +VAE+L S QV Sbjct: 190 LLLDGTLDQLQQLRVRPMAWSCLG--GGRLFNDDYFQ-PLRDELAVVAEELNAGSIEQVV 246 Query: 243 LRWGLQMGHSVLP--KSTNEGRIKENFNVFDWSIPDYMFAKFAE 284 W L++ LP S R++ + + + + Sbjct: 247 NAWVLRLPSQPLPIIGSGKIERVRAAVEAETLKMTRQQWFRIRK 290 >1LQA-A nrPDB Length = 346 Score = 179 bits (455), Expect = 1e-45, Method: Composition-based stats. Identities = 83/337 (24%), Positives = 128/337 (37%), Gaps = 65/337 (19%) Query: 11 NTGAKFPSVGLGTW----QASPGLVGDAVAAAVKIGYRHIDCAQIYG----------NEK 56 ++ + ++GLGT Q S + AV G ID A++Y E Sbjct: 8 HSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTET 67 Query: 57 EIGAVLKKLFEDRVVKREDLFITSKLWCTDH------------DPQDVPEALNRTLKDLQ 104 +G L K RE L I SK+ D +++ EAL+ +LK LQ Sbjct: 68 YVGNWLAKHG-----SREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQ 122 Query: 105 LEYVDLYLIHWPARIKK--GSVGIKPENLLP-VDIPSTWKAMEALYDSGKARAIGVSN-- 159 +Y+DLY +HWP R G +G + P V + T A+ +GK R IGVSN Sbjct: 123 TDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNET 182 Query: 160 -FSTK---KLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLG----- 210 F LAD +L R+ N + L E + +GV L AYS LG Sbjct: 183 AFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLT 242 Query: 211 -----SPGTTWLKSDVLK----------NPILNM---VAEKLGKSPAQVALRWGLQMGHS 252 ++ + + +A + G PAQ+AL + + Sbjct: 243 GKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFV 302 Query: 253 --VLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQ 287 L +T ++K N + + + A+ + Q Sbjct: 303 ASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQ 339 >1PYF-A nrPDB Length = 312 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 69/315 (21%), Positives = 122/315 (38%), Gaps = 70/315 (22%) Query: 19 VGLGTW---------QASPGLVGDAVAAAVKIGYRHIDCAQIYG---NEKEIGAVLKKLF 66 +GLGT + + V A++ G +D A IYG +E+ IG VL++ Sbjct: 16 IGLGTNAVGGHNLYPNLNEETGKELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLREF- 74 Query: 67 EDRVVKREDLFITSKL--------WCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPAR 118 RED+ I +K + D+ P + ++++ +LK L +Y+DL+ IH+P Sbjct: 75 -----NREDVVIATKAAHRKQGNDFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFP-- 127 Query: 119 IKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAV 178 + P D A+ + +GK R+IGVSNFS ++L + + V V Sbjct: 128 ----------DEHTPKD--EAVNALNEMKKAGKIRSIGVSNFSLEQLKEANKDGLVD--V 173 Query: 179 NQVECHPSWRQTK--LQEFCKSKGVHLSAYSPLGSP------------------------ 212 Q E + R+ + + K + Y PL S Sbjct: 174 LQGEYNLLNREAEKTFFPYTKEHNISFIPYFPLVSGLLAGKYTEDTTFPEGDLRNEQEHF 233 Query: 213 GTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQMG--HSVLPKSTNEGRIKENFNVF 270 K ++ K L +AEK + L W L ++P + ++ +N Sbjct: 234 KGERFKENIRKVNKLAPIAEKHNVDIPHIVLAWYLARPEIDILIPGAKRADQLIDNIKTA 293 Query: 271 DWSIPDYMFAKFAEI 285 D ++ + ++ Sbjct: 294 DVTLSQEDISFIDKL 308 >1PZ1-A nrPDB Length = 333 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 73/326 (22%), Positives = 131/326 (40%), Gaps = 69/326 (21%) Query: 11 NTGAKFPSVGLGTWQASPGLVG--------DAVAAAVKIGYRHIDCAQIYG---NEKEIG 59 +TG + +GLGTW + G + + AA+ G ID A YG +E+ +G Sbjct: 8 DTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVG 67 Query: 60 AVLKKLFEDRVVKREDLFITSKL---WCTDH-----DPQDVPEALNRTLKDLQLEYVDLY 111 +K+ KR+ + + +K W + + + E + +LK LQ +Y+DLY Sbjct: 68 KAIKEYM-----KRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLY 122 Query: 112 LIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLEL 171 +HWP + L+P++ T + M+ LYD+GK RAIGVSNFS +++ + Sbjct: 123 QVHWP------------DPLVPIE--ETAEVMKELYDAGKIRAIGVSNFSIEQMDTFRAV 168 Query: 172 ARVPPAVNQVECHPSWRQTK--LQEFCKSKGVHLSAYSPLGSP----------------- 212 A P Q + R+ + + + K + Y L Sbjct: 169 A--PLHTIQPPYNLFEREMEESVLPYAKDNKITTLLYGSLCRGLLTGKMTEEYTFEGDDL 226 Query: 213 -------GTTWLKSDVLKNPILNMVAE-KLGKSPAQVALRWGLQMGHSVLP--KSTNEGR 262 K + L+ +A+ + GKS +A+RW L + + + G+ Sbjct: 227 RNHDPKFQKPRFKEYLSAVNQLDKLAKTRYGKSVIHLAVRWILDQPGADIALWGARKPGQ 286 Query: 263 IKENFNVFDWSIPDYMFAKFAEIEQA 288 ++ + W++ I + Sbjct: 287 LEALSEITGWTLNSEDQKDINTILEN 312 >1GVE-A nrPDB Length = 327 Score = 151 bits (382), Expect = 4e-37, Method: Composition-based stats. Identities = 64/345 (18%), Positives = 126/345 (36%), Gaps = 79/345 (22%) Query: 17 PSVGLGTWQASPGL----VGDAVAAAVKIGYRHIDCAQIYGN--EKEIGAVLKKLFEDRV 70 P+ LG + + +V A ++ G+ ID A +Y N + I L Sbjct: 6 PATVLGAMEMGRRMDVTSSSASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSG 65 Query: 71 VKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPEN 130 K + + ++ P DV L +LK LQ VDL+ +H+P ++ Sbjct: 66 CKVKIATKAAPMFGKTLKPADVRFQLETSLKRLQCPRVDLFYLHFP------------DH 113 Query: 131 LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELAR----VPPAVNQVECHPS 186 P++ T +A L+ GK +G+SN+ + ++A++ L + + P V Q + Sbjct: 114 GTPIE--ETLQACHQLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAI 171 Query: 187 WRQT--KLQEFCKSKGVHLSAYSPLGSP-----------GTTWLKSDVLKNP-------- 225 RQ +L + G+ A++PL +S NP Sbjct: 172 TRQVETELFPCLRHFGLRFYAFNPLAGGLLTGRYKYQDKDGKNPESRFFGNPFSQLYMDR 231 Query: 226 ------------ILNMVAEKLGKSPAQV---ALRW---GLQ----MGHSVLPKSTNEGRI 263 + + G + + A+RW Q G +V+ ++ ++ Sbjct: 232 YWKEEHFNGIALVEKALKTTYGPTAPSMISAAVRWMYHHSQLKGTQGDAVILGMSSLEQL 291 Query: 264 KENFNVFDWSIPDY---MFAKFAEIEQARLVTGSFLVHETLSPYK 305 ++N ++ + A +QA + + HE + ++ Sbjct: 292 EQNL-----ALVEEGPLEPAVVDAFDQAW----NLVAHECPNYFR 327 >2CLP-A nrPDB Length = 347 Score = 143 bits (361), Expect = 1e-34, Method: Composition-based stats. Identities = 59/321 (18%), Positives = 107/321 (33%), Gaps = 71/321 (22%) Query: 25 QASPGLVGDAVAAAVKIGYRHIDCAQIY--GNEKEIGAVLKKLFEDRVVKREDLFITSKL 82 + A ++ G+ ID A +Y G + I L + + L Sbjct: 38 RMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPL 97 Query: 83 WCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKA 142 + P + L +LK LQ VDL+ +H P ++ PV+ T +A Sbjct: 98 FGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------------DHSTPVE--ETLRA 143 Query: 143 MEALYDSGKARAIGVSNFSTKKLADLLELAR----VPPAVNQVECHPSWRQT--KLQEFC 196 L+ GK +G+SN++ ++A++ L + + P V Q + RQ +L Sbjct: 144 CHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCL 203 Query: 197 KSKGVHLSAYSPLGSP---GTTWLKSDVLKNP---------------------------- 225 + G+ A++PL G + K P Sbjct: 204 RHFGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIAL 263 Query: 226 ILNMVAEKLGKSPAQV---ALRW-----GLQ--MGHSVLPKSTNEGRIKENFNVFDWSIP 275 + + G S + LRW LQ G +V+ ++ ++++N Sbjct: 264 VEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAA-----A 318 Query: 276 DY---MFAKFAEIEQARLVTG 293 + A QA + Sbjct: 319 EEGPLEPAVVDAFNQAWHLVA 339 >2C91-A nrPDB Length = 338 Score = 140 bits (354), Expect = 7e-34, Method: Composition-based stats. Identities = 71/348 (20%), Positives = 128/348 (36%), Gaps = 85/348 (24%) Query: 17 PSVGLGTW----QASPGLVGDAVAAAVKIGYRHIDCAQIY--GNEKEIGAVLKKLFEDRV 70 P+ LGT + +V A ++ G+ +D A +Y G + I L Sbjct: 17 PATVLGTMEMGRRMDASASAASVRAFLERGHSELDTAFMYCDGQSENILGGLGLGLGSGD 76 Query: 71 VKREDLFITSKL--W-CTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIK 127 + I +K W P + L +LK LQ VDL+ +H Sbjct: 77 CTVK---IATKANPWEGKSLKPDSIRSQLETSLKRLQCPRVDLFYLH------------A 121 Query: 128 PENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELAR----VPPAVNQVEC 183 P++ PV+ T A L+ GK +G+SN+++ ++A++ L + + P V Q Sbjct: 122 PDHSTPVE--ETLCACHQLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMY 179 Query: 184 HPSWRQT--KLQEFCKSKGVHLSAYSPLGSP---GTTWLKSDVLKNPI------------ 226 + + RQ +L + G+ AY+PL G + K P+ Sbjct: 180 NATTRQVEAELLPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNNWAETY 239 Query: 227 ---------LNMVA--EK-----LGKSPAQV---ALRW-----GLQ--MGHSVLPKSTNE 260 +A EK G + ++ ALRW LQ G +V+ ++ Sbjct: 240 RNRFWKEHHFEAIALVEKALQTTYGTNAPRMTSAALRWMYHHSQLQGTRGDAVILGMSSL 299 Query: 261 GRIKENFNVFDWSIPDY---MFAKFAEIEQARLVTGSFLVHETLSPYK 305 ++++N + A +QA + + HE + ++ Sbjct: 300 EQLEQNLAA-----TEEGPLEPAVVEAFDQAW----NMVAHECPNYFR 338 >2BP1-A nrPDB Length = 360 Score = 139 bits (351), Expect = 1e-33, Method: Composition-based stats. Identities = 70/332 (21%), Positives = 119/332 (35%), Gaps = 81/332 (24%) Query: 21 LGTW----QASPGLVGDAVAAAVKIGYRHIDCAQIY--GNEKEIGAVLKKLFEDRVVKRE 74 LGT + AV A ++ G+ +D A +Y G + I L + + Sbjct: 43 LGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK 102 Query: 75 DLFITSKL--W-CTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENL 131 I +K W P V L +LK LQ VDL+ +H P++ Sbjct: 103 ---IATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLH------------APDHG 147 Query: 132 LPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELAR----VPPAVNQVECHPSW 187 PV+ T A + L+ GK +G+SN+++ ++A++ L + + P V Q + + Sbjct: 148 TPVE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATT 205 Query: 188 RQT--KLQEFCKSKGVHLSAYSPLGSP---------------------GTTWLK---SDV 221 RQ +L + G+ AY+PL G +W + + Sbjct: 206 RQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRF 265 Query: 222 LKNPILNMVA-------EKLGKSPAQV---ALRW-----GLQ--MGHSVLPKSTNEGRIK 264 K +A G S V ALRW LQ G +V+ ++ +++ Sbjct: 266 WKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLE 325 Query: 265 ENFNVFDWSIPDY---MFAKFAEIEQARLVTG 293 +N + A QA + Sbjct: 326 QNLAA-----TEEGPLEPAVVDAFNQAWHLVA 352 >4EXA-A nrPDB Length = 292 Score = 73.1 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 47/237 (19%), Positives = 86/237 (36%), Gaps = 54/237 (22%) Query: 11 NTGAKFPSVGLGTWQ---------------ASPGLVGDAVAAAVKIGYRHIDCAQIYG-N 54 +TG +GLGT + D +A A +G ID A YG + Sbjct: 37 DTGLAVSPLGLGTVKFGRDQGVKYPSGFTIPDDREAADLLALARDLGINLIDTAPAYGRS 96 Query: 55 EKEIGAVLKKLFEDRVVKREDLFITSKLW--------CTDHDPQDVPEALNRTLKDLQLE 106 E+ +G +L+ +RE I SK+ D ++ R+LK L+ + Sbjct: 97 EERLGPLLRG-------QREHWVIVSKVGEEFVDGQSVFDFSAAHTRRSVERSLKRLETD 149 Query: 107 YVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLA 166 ++L L+H +L ++ + + AL G A G+S + + Sbjct: 150 RIELVLVH-----------SDGNDLDILENSEVYPTLAALKREGLIGAYGLSGKTVEGGL 198 Query: 167 DLLELARVPPAVNQVECHPSWR-QTKLQEF--CKSKGVHL-----SAYSPLGSPGTT 215 L V + + R + + E+ +KG+ + S ++ LG+ Sbjct: 199 RALREGD----CAMVTYNLNERAERPVIEYAAAHAKGILVKKALASGHACLGAGQDP 251 >1JPH-A nrPDB Length = 388 Score = 31.8 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 2/56 (3%) Query: 18 SVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDRVVKR 73 VGL W +P + V V + D +Y +E+EIG ++K++ +D R Sbjct: 300 VVGL-DWTVAPKKARECVGKTVTLQGNL-DPCALYASEEEIGQLVKQMLDDFGPHR 353 >4EHI-A nrPDB Length = 534 Score = 31.5 bits (70), Expect = 0.52, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 18/37 (48%), Gaps = 3/37 (8%) Query: 43 YRHIDCAQIYGNEKEIGAV-LKKL--FEDRVVKREDL 76 ++HID +Y N E+G LK R +E+L Sbjct: 383 FKHIDGGFVYQNSDEVGEDELKNAKLMSQREASKEEL 419 >5ZF1-A nrPDB Length = 301 Score = 29.9 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 14/23 (60%) Query: 183 CHPSWRQTKLQEFCKSKGVHLSA 205 CH + KL+ +C++ + ++A Sbjct: 197 CHRYTPKDKLEAYCRNADIIITA 219 >2WUA-A nrPDB Length = 440 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 4/45 (8%) Query: 201 VHLSAY-SPLGSPGTTWLKSDVLKN---PILNMVAEKLGKSPAQV 241 V ++AY SPL LK + P+L + EK +PA+V Sbjct: 36 VIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEV 80 >3Q3N-A nrPDB Length = 500 Score = 29.5 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 14/27 (51%), Gaps = 3/27 (11%) Query: 89 PQDVPEALNRTLKDLQLE---YVDLYL 112 + + R+L DL L+ Y DL+L Sbjct: 295 YEWIIGQFERSLIDLGLDKPWYWDLFL 321 >5BU6-A nrPDB Length = 277 Score = 29.1 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 14/38 (36%) Query: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKA 152 W + + P+ +P D TW + + SG Sbjct: 112 WTDAPAGTKIRLSPKIEVPHDFFMTWAQLREMAQSGLV 149 >3EAG-A nrPDB Length = 326 Score = 28.8 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 37/98 (37%), Gaps = 18/98 (18%) Query: 169 LELARVPPAVNQVE-----CHPSWRQTKLQEF---------CKSKGV-HLSAYSPLGSP- 212 + PP Q+E + + +L EF +G+ + A LG P Sbjct: 34 CDAKMYPPMSTQLEALGIDVYEGFDAAQLDEFKADVYVIGNVAKRGMDVVEAILNLGLPY 93 Query: 213 --GTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQ 248 G WL +VL + + VA GK+ L W L+ Sbjct: 94 ISGPQWLSENVLHHHWVLGVAGTHGKTTTASMLAWVLE 131 >1TLU-A nrPDB Length = 130 Score = 28.8 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 14/44 (31%) Query: 114 HWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGV 157 H + + WKA E L + KA+ + V Sbjct: 64 HLTIHTWPEYGYAAIDLFTCGEDVDPWKAFEHLKKALKAKRVHV 107 >1CP2-A nrPDB Length = 269 Score = 28.4 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 29/77 (37%), Gaps = 9/77 (11%) Query: 192 LQEFCKSKG---VHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQ 248 L F K G +H SP+ + ++ + +P AE+ + R Sbjct: 193 LDAFAKELGSQLIHFVPRSPMVTKAEINKQTVIEYDPT-CEQAEEYRE-----LARKVDA 246 Query: 249 MGHSVLPKSTNEGRIKE 265 V+PK + R++E Sbjct: 247 NELFVIPKPMTQERLEE 263 >4YWJ-A nrPDB Length = 276 Score = 28.4 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 1/64 (1%) Query: 116 PARIKKGSVGIKPENLLPVDIPS-TWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174 P G V + + L+ PS T K +E + +A IG + FS + L E A+ Sbjct: 66 PLSGDLGKVCEEFDVLIDFTHPSVTLKNIEQCRKARRAMVIGTTGFSADEKLLLAEAAKD 125 Query: 175 PPAV 178 P V Sbjct: 126 IPIV 129 >3ZL8-A nrPDB Length = 437 Score = 28.4 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 29/70 (41%), Gaps = 11/70 (15%) Query: 209 LGSPGTTWLKSD--VLKNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKEN 266 L P W+KS +LK+ +A+ L ++ G VL K++ RI+ Sbjct: 365 LSEPEAEWIKSKKIILKSDDPEKIAKD---------LATRVKKGDVVLFKASRAVRIERV 415 Query: 267 FNVFDWSIPD 276 +F+ + Sbjct: 416 LEMFEKELEK 425 >5OWV-A nrPDB Length = 732 Score = 28.0 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 25/61 (40%), Gaps = 8/61 (13%) Query: 239 AQVALRWGLQMGHSV---LPKSTN-EGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGS 294 AQ+ + + G L K+ +I +N +FD+ + + K I+Q L Sbjct: 72 AQICILNLFKSGFISKQDLLKALKILEKISKNTEIFDFILQE----KVQSIDQKALFQND 127 Query: 295 F 295 F Sbjct: 128 F 128 >4A35-A nrPDB Length = 441 Score = 28.0 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 95 ALNRTLKDLQLEYVDLYLIHW--PARIKKGSVGIKPENLLPVDIPS 138 +++ +L++ EYVD H+ P I++ S + ++ Sbjct: 376 SVSASLENRVCEYVDHLHEHFKYPVMIQRASYMPPKDPGYSTEMKE 421 >3IWD-A nrPDB Length = 68 Score = 28.0 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 14/44 (31%) Query: 114 HWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGV 157 H + + WKA E L + KA+ + V Sbjct: 2 HLTIHTWPEYGYAAIDLFTCGEDVDPWKAFEHLKKALKAKRVHV 45 >5LNB-B nrPDB Length = 310 Score = 27.6 bits (60), Expect = 7.5, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 15/33 (45%), Gaps = 3/33 (9%) Query: 79 TSKLWCTDHD---PQDVPEALNRTLKDLQLEYV 108 T+K+ D + L TLK LQL Y+ Sbjct: 248 TAKMINKYFDKNERNSARKNLRHTLKLLQLNYI 280 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.146 0.433 Lambda K H 0.267 0.0447 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,037,362 Number of Sequences: 36641 Number of extensions: 616626 Number of successful extensions: 2066 Number of sequences better than 10.0: 68 Number of HSP's better than 10.0 without gapping: 113 Number of HSP's successfully gapped in prelim test: 23 Number of HSP's that attempted gapping in prelim test: 1612 Number of HSP's gapped (non-prelim): 140 length of query: 315 length of database: 10,336,785 effective HSP length: 97 effective length of query: 218 effective length of database: 6,782,608 effective search space: 1478608544 effective search space used: 1478608544 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 59 (27.2 bits)