BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q09711 (190 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2L2E-A nrPDB 389 e-109 2LCP-A nrPDB 278 1e-75 2JU0-A nrPDB 256 5e-69 1BJF-A nrPDB 247 2e-66 5M6C-E nrPDB 243 4e-65 5T7C-A nrPDB 241 1e-64 6EPA-A nrPDB 229 8e-61 2I94-A nrPDB 184 2e-47 2D8N-A nrPDB 173 5e-44 1S1E-A nrPDB 170 3e-43 1S6C-A nrPDB 170 4e-43 3DD4-A nrPDB 168 1e-42 2JUL-A nrPDB 166 6e-42 1JBA-A nrPDB 130 3e-31 2R2I-A nrPDB 124 3e-29 2NA0-A nrPDB 121 2e-28 2GGZ-A nrPDB 97 5e-21 2E6W-A nrPDB 86 8e-18 2ZFD-A nrPDB 75 2e-14 1UHN-A nrPDB 75 2e-14 4ORC-B nrPDB 73 9e-14 5B8I-B nrPDB 72 1e-13 4IL1-A nrPDB 72 2e-13 1V1G-A nrPDB 72 2e-13 5YPX-A nrPDB 65 2e-11 4JWQ-A nrPDB 52 1e-07 1CLM-A nrPDB 51 3e-07 3KHE-A nrPDB 51 4e-07 5JN2-A nrPDB 50 5e-07 3K21-A nrPDB 50 6e-07 3L19-A nrPDB 50 6e-07 3HZT-A nrPDB 50 7e-07 3LIJ-A nrPDB 50 8e-07 3O4Y-A nrPDB 47 4e-06 2LM5-A nrPDB 47 4e-06 2E30-A nrPDB 47 5e-06 3QRX-A nrPDB 47 7e-06 2N6A-A nrPDB 46 9e-06 3EK4-A nrPDB 46 1e-05 3WFN-B nrPDB 46 1e-05 6O20-F nrPDB 46 1e-05 4E53-A nrPDB 46 1e-05 2F2P-A nrPDB 45 1e-05 2BEC-A nrPDB 45 1e-05 5I0I-E nrPDB 45 2e-05 5A2H-A nrPDB 45 2e-05 3U0K-A nrPDB 44 4e-05 5ZOR-A nrPDB 44 4e-05 1GGZ-A nrPDB 44 4e-05 6HCS-A nrPDB 44 5e-05 4OY4-A nrPDB 44 5e-05 4RGJ-A nrPDB 44 5e-05 1DTL-A nrPDB 44 5e-05 3Q5I-A nrPDB 44 6e-05 4YZB-A nrPDB 43 9e-05 2AAO-A nrPDB 42 1e-04 2L1W-A nrPDB 42 1e-04 5UKG-A nrPDB 42 2e-04 4I2Y-A nrPDB 41 3e-04 3KF9-A nrPDB 41 3e-04 2BL0-C nrPDB 41 3e-04 3NCG-A nrPDB 41 3e-04 1S6I-A nrPDB 40 5e-04 4DS7-A nrPDB 40 5e-04 1DGU-A nrPDB 40 5e-04 2TN4-A nrPDB 40 7e-04 2HPS-A nrPDB 40 8e-04 2LHI-A nrPDB 40 9e-04 1LKJ-A nrPDB 39 0.001 2LHH-A nrPDB 39 0.001 2M97-A nrPDB 39 0.001 1TOP-A nrPDB 39 0.001 2HF5-A nrPDB 39 0.002 2JNX-A nrPDB 38 0.003 5MWC-D nrPDB 37 0.006 1JF0-A nrPDB 37 0.007 5D43-A nrPDB 37 0.007 1OZS-A nrPDB 36 0.010 3E3R-A nrPDB 36 0.011 2GGM-A nrPDB 36 0.012 2M5E-A nrPDB 35 0.018 5Z1Q-A nrPDB 35 0.019 2OBH-A nrPDB 35 0.020 4NQG-A nrPDB 35 0.023 5E37-A nrPDB 35 0.023 1JFJ-A nrPDB 35 0.023 3KPX-A nrPDB 35 0.027 1S36-A nrPDB 34 0.034 4MVF-A nrPDB 34 0.037 3PM8-A nrPDB 34 0.042 3JAX-C nrPDB 34 0.043 2JOJ-A nrPDB 34 0.044 2B1U-A nrPDB 33 0.055 2PMY-A nrPDB 33 0.060 2JNF-A nrPDB 33 0.064 1C7W-A nrPDB 33 0.066 1JC2-A nrPDB 33 0.070 2LAP-A nrPDB 33 0.079 2KN2-A nrPDB 33 0.083 2ROB-A nrPDB 33 0.086 2NCO-A nrPDB 33 0.087 5PAL-A nrPDB 33 0.093 1FW4-A nrPDB 33 0.098 1Y1X-A nrPDB 33 0.11 2RO9-A nrPDB 32 0.11 2LC5-A nrPDB 32 0.13 2M29-A nrPDB 32 0.16 4ZCV-A nrPDB 32 0.17 4P5X-A nrPDB 32 0.17 6MI5-X nrPDB 32 0.18 5ZGM-A nrPDB 32 0.18 2LMV-A nrPDB 32 0.21 5ZH6-A nrPDB 31 0.40 5VE9-A nrPDB 31 0.40 4N5X-A nrPDB 31 0.41 1M39-A nrPDB 30 0.44 4L9M-A nrPDB 30 0.44 3A8R-A nrPDB 30 0.47 4WPX-A nrPDB 30 0.49 4P5W-A nrPDB 30 0.50 2KGR-A nrPDB 30 0.57 2KSZ-A nrPDB 30 0.59 1UHK-A nrPDB 30 0.59 6IIE-A nrPDB 30 0.63 1SL8-A nrPDB 30 0.69 3I5H-B nrPDB 30 0.73 1F55-A nrPDB 30 0.79 1OQP-A nrPDB 30 0.88 2K2I-A nrPDB 30 0.90 2KZ2-A nrPDB 29 1.0 4NSC-A nrPDB 29 1.2 2N7L-C nrPDB 29 1.2 2Q4U-A nrPDB 29 1.2 1TIZ-A nrPDB 29 1.3 1FI6-A nrPDB 29 1.4 2LV7-A nrPDB 29 1.4 4GJF-A nrPDB 29 1.5 5VLN-A nrPDB 28 1.7 2K7C-A nrPDB 28 1.7 3I5I-C nrPDB 28 1.7 2K2A-A nrPDB 28 1.7 5JOJ-A nrPDB 28 1.8 1BU3-A nrPDB 28 1.8 1RTP-1 nrPDB 28 1.9 5JOL-A nrPDB 28 2.0 3IFK-A nrPDB 28 2.0 2I08-A nrPDB 28 2.1 3J04-B nrPDB 28 2.2 5H7D-E nrPDB 28 2.2 2VXO-A nrPDB 28 2.5 2G9B-A nrPDB 28 2.5 4Q57-A nrPDB 28 2.6 1G33-A nrPDB 28 2.6 2AMI-A nrPDB 28 2.6 1RK9-A nrPDB 28 2.8 4MSP-A nrPDB 28 3.0 3AAJ-A nrPDB 28 3.4 4PAL-A nrPDB 28 3.5 3PAT-A nrPDB 28 3.5 5COC-A nrPDB 27 3.6 1IJ5-A nrPDB 27 3.6 3LCP-C nrPDB 27 3.9 5FBH-B nrPDB 27 3.9 6EAZ-A nrPDB 27 4.1 2VRG-A nrPDB 27 4.3 1CB1-A nrPDB 27 4.5 3A4U-B nrPDB 27 5.4 2WCE-A nrPDB 27 5.5 4YGB-B nrPDB 27 5.5 1YX7-A nrPDB 27 5.6 1NYA-A nrPDB 27 5.8 2LVV-A nrPDB 27 5.9 6AGI-A nrPDB 27 6.0 2RO8-A nrPDB 27 6.3 3SIA-A nrPDB 27 6.3 2MA2-A nrPDB 27 6.4 3D3X-A nrPDB 27 7.8 4OKH-A nrPDB 26 8.1 5OTJ-D nrPDB 26 9.1 2YUF-A nrPDB 26 9.1 2KQY-A nrPDB 26 9.5 >2L2E-A nrPDB Length = 190 Score = 389 bits (998), Expect = e-109, Method: Compositional matrix adjust. Identities = 189/189 (100%), Positives = 189/189 (100%) Query: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP Sbjct: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM Sbjct: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS Sbjct: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 Query: 182 ALSLYDGLV 190 ALSLYDGLV Sbjct: 182 ALSLYDGLV 190 >2LCP-A nrPDB Length = 190 Score = 278 bits (710), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 132/190 (69%), Positives = 161/190 (84%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MGKS SKL + +++L R T F +KE+QQWYKGF KDCPSG L+ + FQKIYKQFFPFGD Sbjct: 1 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 60 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 P+ FA +VFNVFD +K+G I+F EFI ALSVTSRG L++KL WAF+LYDLDN+G I+ +E Sbjct: 61 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 ML IVDAIY+MVG+ V+LPE+E+TPEKRV++IF MMDKN DG+LTL+EF EGSK DP+IV Sbjct: 121 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIV 180 Query: 181 SALSLYDGLV 190 ALSLYDGLV Sbjct: 181 QALSLYDGLV 190 >2JU0-A nrPDB Length = 190 Score = 256 bits (653), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 119/190 (62%), Positives = 150/190 (78%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MG SKLS+D L L +ST FD++E+QQW+KGF +DCPSG L + +F KIYKQFFPFG Sbjct: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 P FA ++F VFD D NG+I F+EFI LS TSRG L +KL WAF+LYDL+++G I++DE Sbjct: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 ML IV ++YKM+GSMV L EDE TPE RV KIF +MDKN+DG +TL+EF EGSK DP+I+ Sbjct: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 Query: 181 SALSLYDGLV 190 AL+LYDGL+ Sbjct: 181 GALNLYDGLI 190 >1BJF-A nrPDB Length = 193 Score = 247 bits (630), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 116/183 (63%), Positives = 140/183 (76%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MGK SKL + +QDL+ ST F + E+Q+WYKGF +DCPSGHL+ EF+KIY FFP+GD Sbjct: 1 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD 60 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 S FAE+VF FDA+ +G IDF+EFI ALSVTSRG+L KL WAF +YDLD NG IS E Sbjct: 61 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 ML IV AIYKMV S++K+PEDE TPEKR KIF MD N+DG+L+LEEF G+K DP+IV Sbjct: 121 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIV 180 Query: 181 SAL 183 L Sbjct: 181 RLL 183 >5M6C-E nrPDB Length = 193 Score = 243 bits (619), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 116/183 (63%), Positives = 137/183 (74%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MGK SKL + LQDL +T F + ELQ+WYKGF KDCP+G LN EF+KIY FFP+GD Sbjct: 1 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGD 60 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 S FAE+VF FD + +G IDF+EFI ALSVTSRG L KL+WAF +YDLD NG IS +E Sbjct: 61 ASKFAEHVFRNFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 ML IV AIYKMV S++K+PEDE TPEKR KIF MD N DG+L+LEEF G+K DP+IV Sbjct: 121 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV 180 Query: 181 SAL 183 L Sbjct: 181 RLL 183 >5T7C-A nrPDB Length = 193 Score = 241 bits (616), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 115/182 (63%), Positives = 135/182 (74%) Query: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 GK SKL + LQDL +T F ELQ+WYKGF KDCP+GHL EF+KIY FFP+GD Sbjct: 2 GKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDA 61 Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 S FAE+VF FD + +G IDF+EFI ALSVTSRG+L KL WAF +YDLD NG IS EM Sbjct: 62 SKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEM 121 Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 L IV AIYKMV S++K+PEDE TPEKR +KIF MD N DG+L+LEEF G+K DP+IV Sbjct: 122 LEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVR 181 Query: 182 AL 183 L Sbjct: 182 LL 183 >6EPA-A nrPDB Length = 187 Score = 229 bits (583), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 114/185 (61%), Positives = 141/185 (76%), Gaps = 1/185 (0%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MGK SKL QD + L T F +KE++QW+KGF KDCP+G L + F KIYKQFFP GD Sbjct: 1 MGKKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGD 60 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 PS FA VF VFD + +G I+F+EFI ALS+TSRG L++KL WAF+LYD+DN+G I+ +E Sbjct: 61 PSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 M IVDAIY+MVG + EDE+TP+KRV+KIF+ MDKN D +LTLEEF EGSK DP +V Sbjct: 121 MYNIVDAIYQMVGQQPQT-EDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMV 179 Query: 181 SALSL 185 ALSL Sbjct: 180 QALSL 184 >2I94-A nrPDB Length = 202 Score = 184 bits (468), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 90/183 (49%), Positives = 126/183 (68%), Gaps = 3/183 (1%) Query: 1 MGKSQS-KLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFG 59 MG S+S LS++ L++L +T+F ++EL WY+ F K+CPSG + + EFQ IY +FFP Sbjct: 1 MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEA 60 Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 DP A+A++VF FDA+ +G +DFKE++ AL +TS G+ N KL WAF LYD+D NG IS + Sbjct: 61 DPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKN 120 Query: 120 EMLRIVDAIYKMVGS--MVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDP 177 E+L IV AI+KM+ LPEDE+TPEKR KI+ K D +LT +EF EG+ + Sbjct: 121 EVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIEGTLANK 180 Query: 178 TIV 180 I+ Sbjct: 181 EIL 183 >2D8N-A nrPDB Length = 207 Score = 173 bits (438), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 83/178 (46%), Positives = 124/178 (69%), Gaps = 2/178 (1%) Query: 8 LSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEY 67 LS++ L++L +T+F ++EL WY+ F KDCP+G + + +FQ IY +FFP DP A+A++ Sbjct: 16 LSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQH 75 Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 VF FD++ +G +DFKE++ AL +T+ G+ N KL WAF LYD+D NG IS +E+L IV A Sbjct: 76 VFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMA 135 Query: 128 IYKMVGS--MVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSAL 183 I+KM+ + LP+DE+TPEKR KI+ KN D +LT +EF EG+ + I+ + Sbjct: 136 IFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLI 193 >1S1E-A nrPDB Length = 224 Score = 170 bits (431), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 80/178 (44%), Positives = 116/178 (65%) Query: 13 LQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVF 72 L+ L T F K+ELQ Y+GF +CPSG +N+ F++IY QFFP GD S +A Y+FN F Sbjct: 39 LEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAF 98 Query: 73 DADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D + G + F++F+ ALS+ RG +++KL W F LYD++ +G I+ +EM+ IV AIY M+ Sbjct: 99 DTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMM 158 Query: 133 GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 G EDTP + V+ F MDKNKDG +TL+EF E + D I+ +L L+ ++ Sbjct: 159 GKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM 216 >1S6C-A nrPDB Length = 183 Score = 170 bits (430), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 80/178 (44%), Positives = 116/178 (65%) Query: 13 LQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVF 72 L+ L T F K+ELQ Y+GF +CPSG +N+ F++IY QFFP GD S +A Y+FN F Sbjct: 6 LEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAF 65 Query: 73 DADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D + G + F++F+ ALS+ RG +++KL W F LYD++ +G I+ +EM+ IV AIY M+ Sbjct: 66 DTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMM 125 Query: 133 GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 G EDTP + V+ F MDKNKDG +TL+EF E + D I+ +L L+ ++ Sbjct: 126 GKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM 183 >3DD4-A nrPDB Length = 229 Score = 168 bits (426), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 78/180 (43%), Positives = 118/180 (65%) Query: 11 DQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFN 70 + L+ L ++F KKELQ Y+GF +CPSG +N+ F++IY QFFP GD + +A ++FN Sbjct: 50 EALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFN 109 Query: 71 VFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 FD D NG + F++FI LS+ RG + +KL WAF LYD++ +G I+ +EML I+ AIY Sbjct: 110 AFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYD 169 Query: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 M+G ED P + V F MDKNKDG +T++EF E ++D I+ ++ L++ ++ Sbjct: 170 MMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI 229 >2JUL-A nrPDB Length = 256 Score = 166 bits (420), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 77/180 (42%), Positives = 121/180 (67%), Gaps = 3/180 (1%) Query: 11 DQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFN 70 DQLQ T+F KKELQ Y+GF +CP+G +++ F+ IY QFFP GD + +A ++FN Sbjct: 80 DQLQ---AQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFN 136 Query: 71 VFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 FDAD NG I F++F+ LS+ RG +++KL WAF LYD++ +G I+ +EML I+ +IY Sbjct: 137 AFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD 196 Query: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 M+G ED P + V + F MD+N+DG +T++EF E ++D I++++ L++ ++ Sbjct: 197 MMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFENVI 256 >1JBA-A nrPDB Length = 204 Score = 130 bits (327), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 71/171 (41%), Positives = 102/171 (59%), Gaps = 12/171 (7%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYV---FNVFDADKNGY 79 D +LQ+WYK F ++CPSG L EF K+FF D +YV F FD + + Sbjct: 20 DAAQLQEWYKKFLEECPSGTLFMHEF----KRFFKVPDNEEATQYVEAMFRAFDTNGDNT 75 Query: 80 IDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLP 139 IDF E++ AL++ RG L KL W F++YD D NG I E+L IV++IYK+ + Sbjct: 76 IDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEV 135 Query: 140 EDED-----TPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 E E TPE+ V++IF ++D+N DGQL+L EF EG++RD ++ L + Sbjct: 136 EAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKMLQM 186 >2R2I-A nrPDB Length = 198 Score = 124 bits (310), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 68/163 (41%), Positives = 98/163 (60%), Gaps = 13/163 (7%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD--PSA--FAEYVFNVFDADKNGYID 81 E QWYK F +CPSG L EF KQFF + PSA + E +F FD +K+GYID Sbjct: 15 ECHQWYKKFMTECPSGQLTLYEF----KQFFGLKNLSPSANKYVEQMFETFDFNKDGYID 70 Query: 82 FKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPED 141 F E++ ALS+ +G+++ KL W F+LYD+D NG I E+L I+ AI + + Sbjct: 71 FMEYVAALSLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAI-----RAINRCNE 125 Query: 142 EDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALS 184 T E+ N +F+ +D N DG+L+LEEF EG ++D ++ L+ Sbjct: 126 AMTAEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILT 168 >2NA0-A nrPDB Length = 205 Score = 121 bits (303), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 64/161 (39%), Positives = 97/161 (60%), Gaps = 8/161 (4%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIY--KQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 E QWYK F +CPSG L EF++ + K P+ S + E +F FD +K+GYIDF Sbjct: 17 ECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPW--ASQYVEQMFETFDFNKDGYIDFM 74 Query: 84 EFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDED 143 E+ ALS+ +G++ KL W F+LYD+D NG I DE+L I+ AI ++ + Sbjct: 75 EYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIR----AINPCSDSTM 130 Query: 144 TPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALS 184 T E+ + +F+ +D N DG+L+LEEF EG ++D ++ L+ Sbjct: 131 TAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLT 171 >2GGZ-A nrPDB Length = 211 Score = 96.7 bits (239), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 52/156 (33%), Positives = 86/156 (55%), Gaps = 6/156 (3%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 +E WY+ F + PSG EF+ + + + V+N FD +K+G++DF E Sbjct: 19 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 78 Query: 85 FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDT 144 FI A+++ + ++ KL W F+LYD D NG I +E+L + A+ + G + Sbjct: 79 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL------S 132 Query: 145 PEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 PE+ +N +F+ +D N DG+LTLEEF G +D ++ Sbjct: 133 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 168 >2E6W-A nrPDB Length = 100 Score = 86.3 bits (212), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 38/99 (38%), Positives = 65/99 (65%) Query: 92 TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNK 151 + G +++KL WAF LYD++ +G I+ +EML I+ +IY M+G ED P + V + Sbjct: 2 SHMGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVER 61 Query: 152 IFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 F MD+N+DG +T+EEF E ++D I+S++ L++ ++ Sbjct: 62 FFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI 100 >2ZFD-A nrPDB Length = 226 Score = 74.7 bits (182), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 58/175 (33%), Positives = 87/175 (49%), Gaps = 11/175 (6%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPS----GHLNKSEFQKIYKQFFPFGDPSAFAEYVFNV 71 L R T F E++ Y+ F K + G +NK EFQ F S FA+ VF++ Sbjct: 36 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDL 93 Query: 72 FDADKNGYIDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 FD NG + F+EF ALSV ++DK+ ++FQLYDL G I E+ ++V A Sbjct: 94 FDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 153 Query: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 G +K ED ++K F D DG++ EE+ R P+++ ++L Sbjct: 154 ESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 >1UHN-A nrPDB Length = 189 Score = 74.7 bits (182), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 58/175 (33%), Positives = 87/175 (49%), Gaps = 11/175 (6%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPS----GHLNKSEFQKIYKQFFPFGDPSAFAEYVFNV 71 L R T F E++ Y+ F K + G +NK EFQ F S FA+ VF++ Sbjct: 5 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDL 62 Query: 72 FDADKNGYIDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 FD NG + F+EF ALSV ++DK+ ++FQLYDL G I E+ ++V A Sbjct: 63 FDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 122 Query: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 G +K ED ++K F D DG++ EE+ R P+++ ++L Sbjct: 123 ESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 173 >4ORC-B nrPDB Length = 170 Score = 72.8 bits (177), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 58/175 (33%), Positives = 94/175 (53%), Gaps = 24/175 (13%) Query: 20 TRFDKKELQQWYKGFFK-DCP-SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + FD E+++ K F K D SG L+ EF + P + + V ++FD D N Sbjct: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGN 67 Query: 78 GYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G +DFKEFI +S S +G+ KL +AF++YD+D +G IS E+ +++ MVG+ + Sbjct: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MVGNNL 124 Query: 137 KLPEDEDTP-EKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 K DT ++ V+K DK+ DG+++ EEFC +V L ++ +V Sbjct: 125 K-----DTQLQQIVDKTIINADKDGDGRISFEEFC-------AVVGGLDIHKKMV 167 >5B8I-B nrPDB Length = 171 Score = 72.4 bits (176), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 51/166 (30%), Positives = 88/166 (53%), Gaps = 15/166 (9%) Query: 8 LSQDQLQDLVRSTRFDKKELQQWYKGFFK--DCPSGHLNKSEFQKIYKQFFPFGDPSAFA 65 +S L D+V + FD +E+ + +K F K SG + + EF + P + + Sbjct: 1 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSL-----PQVSSNPLS 55 Query: 66 EYVFNVFDADKNGYIDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 + +FD D G +DF+EF+ LS +S+G +KL +AF++YD+D +G IS E+ + Sbjct: 56 TRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIV 115 Query: 125 VDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 + MVGS +K + ++ V+K D + DG+++ EEF Sbjct: 116 ---LKMMVGSNLK----DMQLQQIVDKTIMEADLDGDGRISFEEFT 154 >4IL1-A nrPDB Length = 823 Score = 71.6 bits (174), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 58/175 (33%), Positives = 94/175 (53%), Gaps = 24/175 (13%) Query: 20 TRFDKKELQQWYKGFFK-DCP-SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + FD E+++ K F K D SG L+ EF + P + + V ++FD D N Sbjct: 170 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGN 224 Query: 78 GYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G +DFKEFI +S S +G+ KL +AF++YD+D +G IS E+ +++ MVG+ + Sbjct: 225 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MVGNNL 281 Query: 137 KLPEDEDTP-EKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 K DT ++ V+K DK+ DG+++ EEFC +V L ++ +V Sbjct: 282 K-----DTQLQQIVDKTIINADKDGDGRISFEEFC-------AVVGGLDIHKKMV 324 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 + N DAD NG IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 111 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ D + DGQ+ EEF + Sbjct: 112 NLGE------KLTDEE------VDEMIREADIDGDGQVNYEEFVQ 144 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/132 (24%), Positives = 60/132 (45%), Gaps = 12/132 (9%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D NGYI E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 89 AFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148 Query: 128 IYKMVGSMVKLPEDE---------DTPE-KRVNKIFNMMDKNKDGQLTLEEFCEGS--KR 175 G E D E KR+ K F +D + G L++EEF ++ Sbjct: 149 KGGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQ 208 Query: 176 DPTIVSALSLYD 187 +P + + ++D Sbjct: 209 NPLVQRVIDIFD 220 Score = 34.7 bits (78), Expect = 0.027, Method: Compositional matrix adjust. Identities = 33/138 (23%), Positives = 54/138 (39%), Gaps = 10/138 (7%) Query: 1 MGKSQSKLSQDQ-----LQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF 55 +GK KL D +++ + + L Q F +G ++ EF + QF Sbjct: 180 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQF 239 Query: 56 FPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW-----AFQLYDL 110 GD + F ++D DK+GYI E L + L D + D Sbjct: 240 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 299 Query: 111 DNNGLISYDEMLRIVDAI 128 D +G IS++E +V + Sbjct: 300 DGDGRISFEEFCAVVGGL 317 >1V1G-A nrPDB Length = 222 Score = 71.6 bits (174), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 53/175 (30%), Positives = 92/175 (52%), Gaps = 11/175 (6%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPS----GHLNKSEFQKIYKQFFPFGDPSAFAEYVFNV 71 L T F +E++ Y+ F K S G ++K EFQ F + FA+ +F+V Sbjct: 25 LASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQ--LALFRNRNRRNLFADRIFDV 82 Query: 72 FDADKNGYIDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 FD +NG I+F EF+ +L V +++K+ +AF+LYDL G I +E+ +V A+ Sbjct: 83 FDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELKEMVVALL- 141 Query: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 +L ED E V+K F D+ DG++ ++E+ + +P+++ ++L Sbjct: 142 ---HESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVSLNPSLIKNMTL 193 >5YPX-A nrPDB Length = 223 Score = 65.1 bits (157), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 48/188 (25%), Positives = 95/188 (50%), Gaps = 15/188 (7%) Query: 2 GKSQSKLSQDQLQDLVRST---RFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPF 58 G SK +Q ++L +++ F K E++ + ++++ F+ I Q F Sbjct: 18 GSHMSKKNQKLAEELYKTSCQKHFTKTEVESLIICYKNLLEGLKMDRNLFRDILHQKFNM 77 Query: 59 GDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISY 118 + + VF FD D + YI E++ LSV RG L++K+ + F ++DL+ +G IS Sbjct: 78 TE-DLLMDRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLDEKMEYTFTVFDLNGDGYISR 136 Query: 119 DEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM----MDKNKDGQLTLEEFCEGSK 174 +EM +++ +VK P +ED P++ + + + MD + D +L+ ++F + Sbjct: 137 EEMFQMLKT------CLVKQPTEED-PDEGIKDLVEIALKKMDHDHDSRLSKKDFKDAVL 189 Query: 175 RDPTIVSA 182 +P ++ A Sbjct: 190 IEPLLLEA 197 >4JWQ-A nrPDB Length = 199 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 38/112 (33%), Positives = 62/112 (55%), Gaps = 11/112 (9%) Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYD 119 P F + + + D+D +G ID+ EF+ A R L+ KLI+ AF+++D+DN+G I+ Sbjct: 92 PQNF-DVLLDQIDSDGSGRIDYTEFLAA--ALDRKHLSKKLIYCAFRVFDVDNDGEITTA 148 Query: 120 EMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 E+ I+ K GS+ + +V K+ +DKN DG++ EFCE Sbjct: 149 ELAHILYNGNKK-GSITQ------KDVNQVKKMIQEVDKNNDGKIDFYEFCE 193 >1CLM-A nrPDB Length = 148 Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 34/104 (32%), Positives = 56/104 (53%), Gaps = 13/104 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGE-LNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 + N DAD NG IDF EF+ ++ + + ++LI AF+++D D NGLIS E+ ++ Sbjct: 51 MINEVDADGNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMT 110 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 + + KL +DE V+++ D + DG + EEF Sbjct: 111 NLGE------KLTDDE------VDEMIREADIDGDGHINYEEFV 142 Score = 33.1 bits (74), Expect = 0.065, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 30/58 (51%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F VFD D NG I E ++ +D++ + D+D +G I+Y+E +R++ Sbjct: 88 AFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMM 145 >3KHE-A nrPDB Length = 191 Score = 50.8 bits (120), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 25/163 (15%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPF-GDP---------SAFAEYV 68 +T + KEL Q ++ + G L++ E + Y++ + GD A +++ Sbjct: 34 TTLEETKELTQIFRQL-DNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHI 92 Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 D D+NGYI++ EF+ ++L+ AFQ +D D +G I+ +E+ R+ Sbjct: 93 LQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFGVT 152 Query: 129 YKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + ++ +++ DKN DG++ EEF E Sbjct: 153 --------------EVDDETWHQVLQECDKNNDGEVDFEEFVE 181 Score = 29.6 bits (65), Expect = 0.79, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 4/53 (7%) Query: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 ++ A +GS KL E+T E + +IF +D N DGQL +E EG ++ Sbjct: 20 KLAQAAMLFMGS--KLTTLEETKE--LTQIFRQLDNNGDGQLDRKELIEGYRK 68 >5JN2-A nrPDB Length = 525 Score = 50.4 bits (119), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 41/143 (28%), Positives = 65/143 (45%), Gaps = 32/143 (22%) Query: 41 GHLNKSEFQKIYKQFFPFG-------DPSAFAEYVFNVFDA---DKNGYIDFKEFICAL- 89 G L+++E + YK+ D SA V V DA DKNGYI++ EF+ Sbjct: 391 GQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEFVTVAM 450 Query: 90 ---SVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPE 146 ++ SR ++L AF+++D DN+G IS E+ I D Sbjct: 451 DRKTLLSR----ERLERAFRMFDSDNSGKISSTELATIFGV--------------SDVDS 492 Query: 147 KRVNKIFNMMDKNKDGQLTLEEF 169 + + + +DKN DG++ +EF Sbjct: 493 ETWKSVLSEVDKNNDGEVDFDEF 515 Score = 32.3 bits (72), Expect = 0.14, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 13/99 (13%) Query: 85 FICALSVTSRGELNDKLIWAFQ-------LYDLDNN--GLISYDEMLRIVDAIYKMVGSM 135 ++ ++ +++R L+ + I + + LDN + + ++ A +GS Sbjct: 309 YVPSMRISARDALDHEWIQTYTKEQISVDVPSLDNAILNIRQFQGTQKLAQAALLYMGS- 367 Query: 136 VKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 KL ++T E + IF+ MDKN DGQL E EG K Sbjct: 368 -KLTSQDETKE--LTAIFHKMDKNGDGQLDRAELIEGYK 403 >3K21-A nrPDB Length = 191 Score = 50.1 bits (118), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 34/104 (32%), Positives = 57/104 (54%), Gaps = 16/104 (15%) Query: 72 FDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVDAIYK 130 D+D +G ID+ EFI A R +L+ KLI+ AF+++D+DN+G I+ E+ I Sbjct: 96 IDSDGSGKIDYTEFIAA--ALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHI------ 147 Query: 131 MVGSMVKLPEDEDTPEKRVNKIFNMM---DKNKDGQLTLEEFCE 171 + + + ++ VN++ M+ DKN DG++ EF E Sbjct: 148 ----LYNGNKKGNITQRDVNRVKRMIRDVDKNNDGKIDFHEFSE 187 >3L19-A nrPDB Length = 214 Score = 50.1 bits (118), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 22/159 (13%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF-------FPFGDPSAFAEYVFNV 71 +++ + KEL ++ K+ G L++ E Y + F + + + Sbjct: 57 TSQEETKELTDIFRHIDKN-GDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGA 115 Query: 72 FDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 D D+NGYID+ EF+ DKL AFQ +D D NG IS DE+ + + Sbjct: 116 ADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFGLDH-- 173 Query: 132 VGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 K ++ + +D N DG + EEFC Sbjct: 174 ------------LESKTWKEMISGIDSNNDGDVDFEEFC 200 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 2/36 (5%) Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEG 172 KL E+T K + IF +DKN DGQL +E +G Sbjct: 55 KLTSQEET--KELTDIFRHIDKNGDGQLDRQELIDG 88 >3HZT-A nrPDB Length = 467 Score = 49.7 bits (117), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 41/163 (25%), Positives = 76/163 (46%), Gaps = 25/163 (15%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPF-GDP---------SAFAEYV 68 +T + KEL Q ++ + G L++ E + Y++ + GD A +++ Sbjct: 308 TTLEETKELTQIFRQL-DNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHI 366 Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 D D+NGYI++ EF+ ++L+ AFQ +D D +G I+ +E+ Sbjct: 367 LQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEEL------- 419 Query: 129 YKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 G + + E +D + +++ DKN DG++ EEF E Sbjct: 420 ----GRLFGVTEVDD---ETWHQVLQECDKNNDGEVDFEEFVE 455 Score = 29.6 bits (65), Expect = 0.81, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 4/53 (7%) Query: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 ++ A +GS KL E+T E + +IF +D N DGQL +E EG ++ Sbjct: 294 KLAQAAMLFMGS--KLTTLEETKE--LTQIFRQLDNNGDGQLDRKELIEGYRK 342 >3LIJ-A nrPDB Length = 494 Score = 49.7 bits (117), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 35/104 (33%), Positives = 48/104 (46%), Gaps = 14/104 (13%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 + D D+NGYID+ EF+ DKL AFQ +D D NG IS DE+ Sbjct: 395 ILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDEL------ 448 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 S+ L E K ++ + +D N DG + EEFC+ Sbjct: 449 -----ASVFGLDHLES---KTWKEMISGIDSNNDGDVDFEEFCK 484 Score = 29.3 bits (64), Expect = 0.94, Method: Compositional matrix adjust. Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 2/36 (5%) Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEG 172 KL E+T E + IF +DKN DGQL +E +G Sbjct: 338 KLTSQEETKE--LTDIFRHIDKNGDGQLDRQELIDG 371 >3O4Y-A nrPDB Length = 196 Score = 47.4 bits (111), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 17/118 (14%) Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYD 119 P F + + + D+D +G ID+ EF+ A R +L+ KLI+ AF+++D+DN+G I+ Sbjct: 89 PPNF-DLLLDQIDSDGSGNIDYTEFLAA--AIDRRQLSKKLIYCAFRVFDVDNDGEITTA 145 Query: 120 EMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMM---DKNKDGQLTLEEFCEGSK 174 E+ + + + + E+ VN++ M+ DKN DG++ EF E K Sbjct: 146 ELAHV----------LFNGNKRGNITERDVNQVKKMIREVDKNGDGKIDFYEFSEMMK 193 >2LM5-A nrPDB Length = 214 Score = 47.4 bits (111), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 14/194 (7%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCP-------SGHLNKSEFQKIYK 53 MG S S+LS++ L + T K+E+ ++ F + P S + F++I Sbjct: 24 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 83 Query: 54 QFFPFGDPSAFAEYVFNVFDAD-KNGYIDFKEFICALSVTSRGELND-KLIWAFQLYDLD 111 P + F E + VF + F++F+ LSV S D K +AF+++D D Sbjct: 84 --LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFD 141 Query: 112 NNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 ++G ++ +++ R+V+ + G +L E ++ ++ I D ++DG + L EF Sbjct: 142 DDGTLNREDLSRLVNCLTGE-GEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQH 198 Query: 172 GSKRDPTIVSALSL 185 R P S+ + Sbjct: 199 VISRSPDFASSFKI 212 >2E30-A nrPDB Length = 195 Score = 47.0 bits (110), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 43/153 (28%), Positives = 73/153 (47%), Gaps = 29/153 (18%) Query: 1 MGKSQSKLSQDQ-LQDLVRSTRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYK-QFF 56 MG S L +D+ L+++ + T F ++ + Y F +G L++ +FQ+I + Sbjct: 1 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAIN 60 Query: 57 PFGDPSAFAEYVFNVFDADKNGYIDFKEFICALS-------------VTSRGELN---DK 100 P GD + N F + ++F+ F+ L+ V LN +K Sbjct: 61 PLGD------RIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNK 114 Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVG 133 L +AF+LYDLD + IS DE+L++ + MVG Sbjct: 115 LHFAFRLYDLDKDEKISRDELLQV---LRMMVG 144 >3QRX-A nrPDB Length = 169 Score = 46.6 bits (109), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 41/163 (25%), Positives = 82/163 (50%), Gaps = 17/163 (10%) Query: 10 QDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVF 69 +DQ + V T K+E+++ + F D SG ++ E K+ + F + + Sbjct: 13 RDQKKGRVGLTEEQKQEIREAFDLFDTDG-SGTIDAKEL-KVAMRALGFEPKKEEIKKMI 70 Query: 70 NVFDADKNGYIDFKEFICALSVTSRGELN--DKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 + D D +G IDF+EF+ ++ GE + ++++ AF+L+D DN+G I+ ++ R+ Sbjct: 71 SEIDKDGSGTIDFEEFLTMMTA-KMGERDSREEILKAFRLFDDDNSGTITIKDLRRVA-- 127 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 K +G E+ E+ + ++ D+N D ++ +EF Sbjct: 128 --KELG--------ENLTEEELQEMIAEADRNDDNEIDEDEFI 160 >2N6A-A nrPDB Length = 173 Score = 46.2 bits (108), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 + N DAD NG IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ Sbjct: 53 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 112 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ D + DGQ+ EEF + Sbjct: 113 NLGE------KLTDEE------VDEMIREADIDGDGQVNYEEFVQ 145 Score = 35.0 bits (79), Expect = 0.018, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 33/67 (49%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D NGYI E ++ ++++ + D+D +G ++Y+E ++++ Sbjct: 90 AFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTG 149 Query: 128 IYKMVGS 134 GS Sbjct: 150 ASTAAGS 156 >3EK4-A nrPDB Length = 451 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 + N DAD NG IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ Sbjct: 354 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 413 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ D + DGQ+ EEF + Sbjct: 414 NLGE------KLTDEE------VDEMIREADIDGDGQVNYEEFVQ 446 Score = 33.9 bits (76), Expect = 0.048, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 32/60 (53%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D NGYI E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 391 AFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 450 >3WFN-B nrPDB Length = 182 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVD 126 + N DAD NG IDF EF+ ++ + +++ I AF+++D D NG IS E+ ++ Sbjct: 58 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 117 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ D + DGQ+ EEF + Sbjct: 118 NLGE------KLTDEE------VDEMIREADIDGDGQVNYEEFVQ 150 Score = 33.5 bits (75), Expect = 0.060, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 32/60 (53%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D NGYI E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 95 AFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 154 >6O20-F nrPDB Length = 169 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVD 126 + N DAD NG IDF EF+ ++ + +++ I AF+++D D NG IS E+ ++ Sbjct: 72 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 131 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ D + DGQ+ EEF + Sbjct: 132 NLGE------KLTDEE------VDEMIREADIDGDGQVNYEEFVQ 164 Score = 33.5 bits (75), Expect = 0.050, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 32/60 (53%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D NGYI E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 109 AFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 168 >4E53-A nrPDB Length = 185 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 + N DAD NG IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ Sbjct: 59 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 118 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ D + DGQ+ EEF + Sbjct: 119 NLGE------KLTDEE------VDEMIREADIDGDGQVNYEEFVQ 151 Score = 32.7 bits (73), Expect = 0.10, Method: Compositional matrix adjust. Identities = 15/58 (25%), Positives = 31/58 (53%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F VFD D NGYI E ++ ++++ + D+D +G ++Y+E ++++ Sbjct: 96 AFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 >2F2P-A nrPDB Length = 179 Score = 45.4 bits (106), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 40/149 (26%), Positives = 71/149 (47%), Gaps = 19/149 (12%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEY--VFNVFDADKNGYIDFK 83 E ++ + F KD G + E + + G AE + N DAD NG IDF Sbjct: 12 EFKEAFSLFDKDG-DGTITTKELGTVMR---SLGQNPTEAELQDMINEVDADGNGTIDFP 67 Query: 84 EFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDE 142 EF+ ++ + + +++ AF+++D D NG IS E+ ++ + + KL ++E Sbjct: 68 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE------KLTDEE 121 Query: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 V+++ D + DGQ+ EEF + Sbjct: 122 ------VDEMIREADIDGDGQVNYEEFVQ 144 Score = 33.5 bits (75), Expect = 0.059, Method: Compositional matrix adjust. Identities = 20/88 (22%), Positives = 41/88 (46%) Query: 40 SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND 99 +G ++ EF + + D F VFD D NGYI E ++ ++ Sbjct: 61 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE 120 Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDA 127 ++ + D+D +G ++Y+E ++++ A Sbjct: 121 EVDEMIREADIDGDGQVNYEEFVQMMTA 148 >2BEC-A nrPDB Length = 202 Score = 45.4 bits (106), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 39/177 (22%) Query: 18 RSTRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYK-QFFPFGDPSAFAEYVFNVFDA 74 R T F + L + + F G+L++ + Q+I P GD + F Sbjct: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD------RIIESFFP 72 Query: 75 DKNGYIDFKEFICALS--------------------VTSRGELNDKLIWAFQLYDLDNNG 114 D + +DF F+ L+ + SR +KL +AFQLYDLD +G Sbjct: 73 DGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSR---RNKLHYAFQLYDLDRDG 129 Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 IS EML++ + MVG V E+ E ++ D++ DG ++ EF + Sbjct: 130 KISRHEMLQV---LRLMVGVQVT----EEQLENIADRTVQEADEDGDGAVSFVEFTK 179 >5I0I-E nrPDB Length = 145 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVD 126 + N DAD NG IDF EF+ ++ + +++ I AF+++D D NG IS E+ ++ Sbjct: 50 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 109 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ D + DGQ+ EEF + Sbjct: 110 NLGE------KLTDEE------VDEMIREADIDGDGQVNYEEFVQ 142 Score = 32.3 bits (72), Expect = 0.12, Method: Compositional matrix adjust. Identities = 19/86 (22%), Positives = 40/86 (46%) Query: 40 SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND 99 +G ++ EF + + D F VFD D NGYI E ++ ++ Sbjct: 59 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE 118 Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIV 125 ++ + D+D +G ++Y+E ++++ Sbjct: 119 EVDEMIREADIDGDGQVNYEEFVQMM 144 >5A2H-A nrPDB Length = 149 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 13/104 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 + N DAD NG IDF EF+ ++ + + ++L AF+++D D NG IS E+ ++ Sbjct: 52 MINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMT 111 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 + + KL ++E V+++ D + DGQ+ EEF Sbjct: 112 NLGE------KLTDEE------VDEMIREADVDGDGQINYEEFV 143 Score = 33.5 bits (75), Expect = 0.054, Method: Compositional matrix adjust. Identities = 19/86 (22%), Positives = 42/86 (48%) Query: 40 SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND 99 +G ++ EF + + D + F VFD D+NG+I E ++ ++ Sbjct: 61 NGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDE 120 Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIV 125 ++ + D+D +G I+Y+E ++++ Sbjct: 121 EVDEMIREADVDGDGQINYEEFVKVM 146 >3U0K-A nrPDB Length = 442 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 + N DAD +G IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ Sbjct: 345 MINEVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 404 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ D + DGQ+ EEF + Sbjct: 405 NLGE------KLTDEE------VDEMIREADIDGDGQVNYEEFVQ 437 Score = 33.9 bits (76), Expect = 0.045, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 32/60 (53%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D NGYI E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 382 AFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 441 >5ZOR-A nrPDB Length = 149 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 12/108 (11%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGEL-NDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 FN+FDAD +G ID +E A+ G+L D++ + + + NGLI Y E R+V Sbjct: 12 AFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYGEFERMVK 71 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 + +M +D+PE+ V K F + D +K G+++ E +K Sbjct: 72 S--RMA--------QKDSPEE-VLKAFQLFDLDKKGKISFANLKEVAK 108 Score = 39.7 bits (91), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 15/132 (11%) Query: 40 SGHLNKSEFQKIYKQFFPFGD-PSAFAEYVFNVFDADKNGYIDFKEFICAL-SVTSRGEL 97 SG ++ E K FGD P E + + NG I++ EF + S ++ + Sbjct: 21 SGAIDAEEMALAMKGL-GFGDLPRDEVERTVRSMNTNANGLIEYGEFERMVKSRMAQKDS 79 Query: 98 NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMD 157 ++++ AFQL+DLD G IS+ + + K++G E+ + + ++ D Sbjct: 80 PEEVLKAFQLFDLDKKGKISFANLKEVA----KLLG--------ENPGDDVLQEMIAEAD 127 Query: 158 KNKDGQLTLEEF 169 ++ DG+++ EEF Sbjct: 128 EDGDGEVSFEEF 139 Score = 29.6 bits (65), Expect = 0.93, Method: Compositional matrix adjust. Identities = 28/118 (23%), Positives = 42/118 (35%), Gaps = 16/118 (13%) Query: 19 STRFDKKELQQWYKGF-FKDCP---------------SGHLNKSEFQKIYKQFFPFGDPS 62 S D +E+ KG F D P +G + EF+++ K D Sbjct: 21 SGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYGEFERMVKSRMAQKDSP 80 Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 F +FD DK G I F + +D L D D +G +S++E Sbjct: 81 EEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPGDDVLQEMIAEADEDGDGEVSFEE 138 >1GGZ-A nrPDB Length = 148 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 13/100 (13%) Query: 72 FDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVDAIYK 130 D D NG +DF EF+ ++ + N++ I AF+++D D NG +S E+ + Sbjct: 55 IDRDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHV------ 108 Query: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 M +L E ++ V+++ D + DGQ+ EEF Sbjct: 109 ----MTRLG--EKLSDEEVDEMIRAADTDGDGQVNYEEFV 142 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 14/58 (24%), Positives = 30/58 (51%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F VFD D NG++ E ++ ++++ + D D +G ++Y+E +R++ Sbjct: 88 AFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVL 145 >6HCS-A nrPDB Length = 167 Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 55/105 (52%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVD 126 + N DAD NG IDF EF+ ++ + +++ I AF+++D D NG IS E+ + Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMT 111 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ D + DGQ+ EEF + Sbjct: 112 NLGE------KLTDEE------VDEMIREADIDGDGQVNYEEFVQ 144 Score = 34.3 bits (77), Expect = 0.035, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 6/69 (8%) Query: 68 VFNVFDADKNGYI---DFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 F VFD D NGYI + + F+ L E D++I D+D +G ++Y+E +++ Sbjct: 89 AFRVFDKDGNGYISAAELRHFMTNLGEKLTDEEVDEMIRE---ADIDGDGQVNYEEFVQM 145 Query: 125 VDAIYKMVG 133 + A + G Sbjct: 146 MTAKLEGTG 154 >4OY4-A nrPDB Length = 415 Score = 43.5 bits (101), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVD 126 + N DAD +G IDF EF+ ++ + +++ I AF+++D D NG IS E+ ++ Sbjct: 59 MINEVDADGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 118 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ D + DGQ+ EEF + Sbjct: 119 NLGE------KLTDEE------VDEMIREADIDGDGQVNYEEFVQ 151 Score = 33.5 bits (75), Expect = 0.055, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 32/60 (53%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D NGYI E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 96 AFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 155 >4RGJ-A nrPDB Length = 520 Score = 43.5 bits (101), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 29/180 (16%) Query: 3 KSQSKLSQDQLQDL-VRSTRFDK-KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPF-G 59 +S KL+Q L + + T D+ KEL + +K K+ G L+++E YK+ G Sbjct: 347 QSTQKLAQAALLYMGSKLTTIDETKELTKIFKKMDKN-GDGQLDRNELIIGYKELLKLKG 405 Query: 60 DPS-----AFAEY----VFNVFDADKNGYIDFKEFICALSVTSRGELN-DKLIWAFQLYD 109 + + A EY + N D D+NGYI++ EF+ +S+ + L+ ++L AF+L+D Sbjct: 406 EDTSDLDNAAIEYEVDQILNSIDLDQNGYIEYSEFL-TVSIDRKLLLSTERLEKAFKLFD 464 Query: 110 LDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 D +G IS +E+ ++ D + + +D+N DG++ +EF Sbjct: 465 KDGSGKISANELAQLFGL--------------SDVSSECWKTVLKEVDQNNDGEIDFKEF 510 Score = 28.9 bits (63), Expect = 1.3, Method: Compositional matrix adjust. Identities = 15/28 (53%), Positives = 16/28 (57%) Query: 147 KRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 K + KIF MDKN DGQL E G K Sbjct: 371 KELTKIFKKMDKNGDGQLDRNELIIGYK 398 >1DTL-A nrPDB Length = 161 Score = 43.5 bits (101), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 35/156 (22%), Positives = 68/156 (43%), Gaps = 17/156 (10%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 T K E + + F G ++ E K+ + P E + V D D +G Sbjct: 13 TEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEV-DEDGSGT 71 Query: 80 IDFKEFICALSVT----SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 +DF EF+ + + S+G+ ++L F+++D + +G I +E+ ++ A + + Sbjct: 72 VDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETI--- 128 Query: 136 VKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 E + ++ DKN DG++ +EF E Sbjct: 129 ---------TEDDIEELMKDGDKNNDGRIDYDEFLE 155 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 30/61 (49%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 +F +FD + +GYID +E L T D + + D +N+G I YDE L + Sbjct: 100 LFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKG 159 Query: 128 I 128 + Sbjct: 160 V 160 >3Q5I-A nrPDB Length = 504 Score = 43.5 bits (101), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 44/158 (27%), Positives = 67/158 (42%), Gaps = 22/158 (13%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPF----GDPSAFAEYVFNVF-- 72 +T ++KEL +K K+ G L+K E + Y F G+ E V N+ Sbjct: 349 TTLEERKELTDIFKKLDKN-GDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKE 407 Query: 73 -DADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 D DKNGYI++ EFI ++L AF L+D D +G I+ +E+ + Sbjct: 408 VDFDKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLFGLT--- 464 Query: 132 VGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 EK N + D+NKD + +EF Sbjct: 465 -----------SISEKTWNDVLGEADQNKDNMIDFDEF 491 Score = 28.1 bits (61), Expect = 2.1, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 4/50 (8%) Query: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEG 172 ++ A +GS + E+ K + IF +DKN DGQL +E EG Sbjct: 335 KLAQAAILFIGSKLTTLEER----KELTDIFKKLDKNGDGQLDKKELIEG 380 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 6/63 (9%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGE--LNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 FN+FD DK+G I +E +TS E ND L A D + + +I +DE + ++ Sbjct: 440 AFNLFDTDKSGKITKEELANLFGLTSISEKTWNDVLGEA----DQNKDNMIDFDEFVSMM 495 Query: 126 DAI 128 I Sbjct: 496 HKI 498 >4YZB-A nrPDB Length = 491 Score = 42.7 bits (99), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 35/139 (25%), Positives = 56/139 (40%), Gaps = 24/139 (17%) Query: 41 GHLNKSEFQKIYKQFFPFG-------DPSAF---AEYVFNVFDADKNGYIDFKEFICALS 90 G L+K E + Y + D SA E V + D DKNG+I++ EF+ Sbjct: 354 GQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLDAVDFDKNGFIEYSEFVTVAM 413 Query: 91 VTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVN 150 +L AF ++D D +G IS E+ I + + Sbjct: 414 DRKTLLSRQRLERAFGMFDADGSGKISSSELATIFGV--------------SEVDSETWR 459 Query: 151 KIFNMMDKNKDGQLTLEEF 169 ++ +D+N DG++ EEF Sbjct: 460 RVLAEVDRNNDGEVDFEEF 478 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 20/36 (55%), Positives = 24/36 (66%), Gaps = 2/36 (5%) Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEG 172 KL +E+T E +NKIF MDKN DGQL +E EG Sbjct: 331 KLTTNEETVE--LNKIFQRMDKNGDGQLDKQELMEG 364 >2AAO-A nrPDB Length = 166 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 14/98 (14%) Query: 73 DADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D D +G ID+KEFI A ++ E D L AF +D D +G I+ DE+ + Sbjct: 73 DVDNSGTIDYKEFIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQAC------- 125 Query: 133 GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 E+ + R+ ++ +D++ DG++ EF Sbjct: 126 -------EEFGVEDVRIEELMRDVDQDNDGRIDYNEFV 156 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 15/107 (14%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 +FN+ DADK+G I F+E L +++ Q D+DN+G I Y E + Sbjct: 32 MFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTIDYKEFIAATLH 91 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLT---LEEFCE 171 + K+ E + F DK+ G +T L++ CE Sbjct: 92 LNKI------------EREDHLFAAFTYFDKDGSGYITPDELQQACE 126 Score = 31.2 bits (69), Expect = 0.26, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 19/27 (70%) Query: 149 VNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + ++FNM+D +K GQ+T EE G KR Sbjct: 29 LKEMFNMIDADKSGQITFEELKAGLKR 55 Score = 26.2 bits (56), Expect = 9.4, Method: Compositional matrix adjust. Identities = 15/56 (26%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 34 FFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL 89 +F SG++ E Q+ ++F G E + D D +G ID+ EF+ + Sbjct: 107 YFDKDGSGYITPDELQQACEEF---GVEDVRIEELMRDVDQDNDGRIDYNEFVAMM 159 >2L1W-A nrPDB Length = 149 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 13/99 (13%) Query: 73 DADKNGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 DAD NG I+F EF+ ++ + + ++L AF+++D D NG IS E+ + M Sbjct: 56 DADGNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHV------M 109 Query: 132 VGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 + KL ++E V ++ D + DGQ+ EEF Sbjct: 110 INLGEKLTDEE------VEQMIKEADLDGDGQVNYEEFV 142 Score = 35.0 bits (79), Expect = 0.021, Method: Compositional matrix adjust. Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 11/102 (10%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F +FD D +G I +E + + ++L D D NG I +DE L + Sbjct: 15 AFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSL--- 71 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 M K +D D E+ + + F + DK+++G ++ E Sbjct: 72 -------MAKKVKDTD-AEEELKEAFKVFDKDQNGYISASEL 105 Score = 33.1 bits (74), Expect = 0.067, Method: Compositional matrix adjust. Identities = 27/120 (22%), Positives = 56/120 (46%), Gaps = 3/120 (2%) Query: 8 LSQDQLQDLVRSTRFD--KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFA 65 ++ ++L ++RS + ++ELQ D +G + EF + + D Sbjct: 27 ITVEELATVIRSLDQNPTEEELQDMISEVDAD-GNGTIEFDEFLSLMAKKVKDTDAEEEL 85 Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 + F VFD D+NGYI E + ++++ + DLD +G ++Y+E ++++ Sbjct: 86 KEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMM 145 >5UKG-A nrPDB Length = 419 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 54/105 (51%), Gaps = 13/105 (12%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVD 126 + N DAD +G DF EF+ ++ + ++ I AF+++D D NG I E+ ++ Sbjct: 322 MINEVDADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMT 381 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + + KL ++E V+++ + D + DGQ+ EEF + Sbjct: 382 DLGE------KLTDEE------VDEMIRVADIDGDGQVNYEEFVQ 414 Score = 34.7 bits (78), Expect = 0.023, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 33/60 (55%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D NGYI E ++ ++++ ++ D+D +G ++Y+E ++++ A Sbjct: 359 AFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTA 418 >4I2Y-A nrPDB Length = 421 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 21/109 (19%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELND-----KLIWAFQLYDLDNNGLISYDEML 122 + N DAD +G DF EF+ ++ ++ND ++ AF+++D D NG I E+ Sbjct: 324 MINEVDADGDGTFDFPEFLTMMAR----KMNDTDSEEEIREAFRVFDKDGNGYIGAAELR 379 Query: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 ++ + + KL ++E V+++ + D + DGQ+ EEF + Sbjct: 380 HVMTDLGE------KLTDEE------VDEMIRVADIDGDGQVNYEEFVQ 416 Score = 35.0 bits (79), Expect = 0.018, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 33/60 (55%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D NGYI E ++ ++++ ++ D+D +G ++Y+E ++++ A Sbjct: 361 AFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTA 420 >3KF9-A nrPDB Length = 149 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 37/148 (25%), Positives = 75/148 (50%), Gaps = 17/148 (11%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 K+E+++ + F D SG ++ E K+ + F + + D D +G IDF+ Sbjct: 7 KQEIREAFDLFDTDG-SGTIDAKEL-KVAMRALGFEPKKEEIKKMIADIDKDGSGTIDFE 64 Query: 84 EFICALSVTSRGELN--DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPED 141 EF+ ++ GE + ++++ AF+L+D D G IS+ + R+ K +G Sbjct: 65 EFLQMMTA-KMGERDSREEIMKAFRLFDDDETGKISFKNLKRVA----KELG-------- 111 Query: 142 EDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 E+ ++ + ++ + D++ DG++ EEF Sbjct: 112 ENMTDEELQEMIDEADRDGDGEVNEEEF 139 >2BL0-C nrPDB Length = 142 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 40 SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELN- 98 +G + K Q + KQF +P+AF E +FN DA NG I F EF+ + + + Sbjct: 20 TGFITKEGLQTVLKQFGVRVEPAAFNE-MFNEADATGNGKIQFPEFLSMMGRRMKQTTSE 78 Query: 99 DKLIWAFQLYDLDNNGLI 116 D L AF+ +D + G I Sbjct: 79 DILRQAFRTFDPEGTGYI 96 >3NCG-A nrPDB Length = 486 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 40/154 (25%), Positives = 68/154 (44%), Gaps = 28/154 (18%) Query: 22 FDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 D+ EL + Y F K S L ++E I Q + + + D D +G Sbjct: 348 LDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQI----------DSLMPLLDMDGSGS 397 Query: 80 IDFKEFICALSVTSRGEL--NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 I++ EFI S R L +++ AF+++D D +G IS E+ ++ + S ++ Sbjct: 398 IEYSEFIA--SAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKL----FSQADSSIQ 451 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + E + I +D NKDG++ EF E Sbjct: 452 MEE--------LESIIEQVDNNKDGEVDFNEFVE 477 Score = 28.9 bits (63), Expect = 1.3, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 8/82 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVF---DA 74 R+ ++ +++ +K F KD SG ++ E K++ Q D S E + ++ D Sbjct: 410 RTILLSRERMERAFKMFDKD-GSGKISTKELFKLFSQ----ADSSIQMEELESIIEQVDN 464 Query: 75 DKNGYIDFKEFICALSVTSRGE 96 +K+G +DF EF+ L R E Sbjct: 465 NKDGEVDFNEFVEMLQNFVRNE 486 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 20/83 (24%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVG--SMVKLPEDEDTPEKRVNKIFNMMD 157 +L F+ D +N+G++ DE++R ++ G S + + T E +++ + ++D Sbjct: 332 QLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLLD 391 Query: 158 KNKDGQLTLEEFCEGSKRDPTIV 180 + G + EF S D TI+ Sbjct: 392 MDGSGSIEYSEFI-ASAIDRTIL 413 >1S6I-A nrPDB Length = 188 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 14/103 (13%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 + + D DK+G ID+ EFI A ++ E + L+ AF +D D +G I+ DE+ + Sbjct: 51 LMDAADIDKSGTIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQAC-- 108 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 +D + ++ + +D++ DGQ+ EF Sbjct: 109 ------------KDFGLDDIHIDDMIKEIDQDNDGQIDYGEFA 139 Score = 30.8 bits (68), Expect = 0.41, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 18/89 (20%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F++ D DN+G I++DE+ D + K VGS + E + + + D +K G + Sbjct: 16 FKMIDTDNSGTITFDEL---KDGL-KRVGS--------ELMESEIKDLMDAADIDKSGTI 63 Query: 165 TLEEFCEGS------KRDPTIVSALSLYD 187 EF + +R+ +VSA S +D Sbjct: 64 DYGEFIAATVHLNKLEREENLVSAFSYFD 92 Score = 27.7 bits (60), Expect = 2.9, Method: Compositional matrix adjust. Identities = 26/107 (24%), Positives = 44/107 (41%), Gaps = 12/107 (11%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 +F + D D +G I F E L + ++ D+D +G I Y E Sbjct: 15 LFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEF------ 68 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 + + V L + E E+ + F+ DK+ G +TL+E + K Sbjct: 69 ----IAATVHLNKLE--REENLVSAFSYFDKDGSGYITLDEIQQACK 109 >4DS7-A nrPDB Length = 147 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 30/106 (28%), Positives = 55/106 (51%), Gaps = 7/106 (6%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEF 85 E ++ + F KD SG ++ SE + + + A+ + N D D N I+F EF Sbjct: 12 EFKEAFALFDKD-NSGSISASELATVMRSLGLSPSEAEVAD-LMNEIDVDGNHAIEFSEF 69 Query: 86 ICALSVTSRGELND---KLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 + +S + ND +L+ AF+++D + +GLIS E+ ++ +I Sbjct: 70 LALMSRQLK--CNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI 113 >1DGU-A nrPDB Length = 183 Score = 40.0 bits (92), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 5/124 (4%) Query: 64 FAEYVFNVFDAD-KNGYIDFKEFICALSVTSRGELND-KLIWAFQLYDLDNNGLISYDEM 121 F E + VF + F++F+ LSV S D K +AF+++D D++G ++ +++ Sbjct: 61 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 120 Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 R+V+ + G +L E ++ ++ I D ++DG + L EF R P S Sbjct: 121 SRLVNCLTGE-GEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFAS 177 Query: 182 ALSL 185 + + Sbjct: 178 SFKI 181 >2TN4-A nrPDB Length = 159 Score = 39.7 bits (91), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 10/105 (9%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F++FDAD G I KE + + + ++L + D D +G I ++E L ++ Sbjct: 22 AFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMM-- 79 Query: 128 IYKMVGSMVKLPED-EDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + ++ ED + E+ + ++F + D+N DG + EE E Sbjct: 80 -------VRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAE 117 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 25/107 (23%), Positives = 51/107 (47%), Gaps = 16/107 (14%) Query: 68 VFNVFDADKNGYIDFKEFIC----ALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 + D D +G IDF+EF+ + ++G+ ++L F+++D + +G I +E+ Sbjct: 58 IIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAE 117 Query: 124 IVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 I ++ G V ++ + + DKN DG++ +EF Sbjct: 118 I----FRASGEHV--------TDEEIESLMKDGDKNNDGRIDFDEFL 152 Score = 33.5 bits (75), Expect = 0.059, Method: Compositional matrix adjust. Identities = 15/61 (24%), Positives = 34/61 (55%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 +F +FD + +GYID +E + ++++ + D +N+G I +DE L++++ Sbjct: 98 LFRIFDRNADGYIDAEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMMEG 157 Query: 128 I 128 + Sbjct: 158 V 158 >2HPS-A nrPDB Length = 186 Score = 39.7 bits (91), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 29/59 (49%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 +++ D DK+GY+ EF L +DK I F D + NG IS DE L V+ Sbjct: 107 MYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFLVTVN 165 >2LHI-A nrPDB Length = 176 Score = 39.7 bits (91), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 7/106 (6%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEF 85 E ++ + F KD +G ++ SE + + A + N D D N I+F EF Sbjct: 12 EFKEAFALFDKD-NNGSISSSELATVMRSL-GLSPSEAEVNDLMNEIDVDGNHQIEFSEF 69 Query: 86 ICALSVTSRGELND---KLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 + +S + ND +L+ AF+++D + +GLIS E+ ++ +I Sbjct: 70 LALMSRQLKS--NDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI 113 Score = 29.6 bits (65), Expect = 0.81, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 12/67 (17%) Query: 104 AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 AF L+D DNNG IS E+ ++ ++ E VN + N +D + + Q Sbjct: 16 AFALFDKDNNGSISSSELATVMRSLGL------------SPSEAEVNDLMNEIDVDGNHQ 63 Query: 164 LTLEEFC 170 + EF Sbjct: 64 IEFSEFL 70 >1LKJ-A nrPDB Length = 146 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/115 (24%), Positives = 57/115 (49%), Gaps = 8/115 (6%) Query: 19 STRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 S+ ++++ ++ + F F +G ++ SE + + A + N D D Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSL-GLSPSEAEVNDLMNEIDVDG 59 Query: 77 NGYIDFKEFICALSVTSRGELND---KLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 N I+F EF+ +S + ND +L+ AF+++D + +GLIS E+ ++ +I Sbjct: 60 NHQIEFSEFLALMSRQLKS--NDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI 112 Score = 29.6 bits (65), Expect = 0.87, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 12/67 (17%) Query: 104 AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 AF L+D DNNG IS E+ ++ ++ E VN + N +D + + Q Sbjct: 15 AFALFDKDNNGSISSSELATVMRSLGL------------SPSEAEVNDLMNEIDVDGNHQ 62 Query: 164 LTLEEFC 170 + EF Sbjct: 63 IEFSEFL 69 >2LHH-A nrPDB Length = 128 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/115 (24%), Positives = 57/115 (49%), Gaps = 8/115 (6%) Query: 19 STRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 S+ ++++ ++ + F F +G ++ SE + + A + N D D Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSL-GLSPSEAEVNDLMNEIDVDG 59 Query: 77 NGYIDFKEFICALSVTSRGELND---KLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 N I+F EF+ +S + ND +L+ AF+++D + +GLIS E+ ++ +I Sbjct: 60 NHQIEFSEFLALMSRQLKS--NDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI 112 Score = 29.6 bits (65), Expect = 0.85, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 12/67 (17%) Query: 104 AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 AF L+D DNNG IS E+ ++ ++ E VN + N +D + + Q Sbjct: 15 AFALFDKDNNGSISSSELATVMRSLGL------------SPSEAEVNDLMNEIDVDGNHQ 62 Query: 164 LTLEEFC 170 + EF Sbjct: 63 IEFSEFL 69 >2M97-A nrPDB Length = 69 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 34/60 (56%) Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 F +FD D NG+ID +EF + +T ++ + F D D NG I +DE L++++ + Sbjct: 9 FRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFLKMMENV 68 Score = 30.0 bits (66), Expect = 0.57, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 12/70 (17%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 +L F+++D D NG I +E G +++L ++ T E V++IF D + Sbjct: 4 ELSECFRIFDKDGNGFIDREEF-----------GDIIRLTGEQLTDED-VDEIFGDSDTD 51 Query: 160 KDGQLTLEEF 169 K+G++ +EF Sbjct: 52 KNGRIDFDEF 61 Score = 28.9 bits (63), Expect = 1.3, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 6/65 (9%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD--PSAFAEYVFNVFDADKNGYID 81 ++EL + ++ F KD +G +++ EF I + G+ + +F D DKNG ID Sbjct: 2 EEELSECFRIFDKD-GNGFIDREEFGDIIR---LTGEQLTDEDVDEIFGDSDTDKNGRID 57 Query: 82 FKEFI 86 F EF+ Sbjct: 58 FDEFL 62 >1TOP-A nrPDB Length = 162 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 26/106 (24%), Positives = 51/106 (48%), Gaps = 16/106 (15%) Query: 68 VFNVFDADKNGYIDFKEFICAL----SVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 + D D +G IDF+EF+ + ++G+ ++L F+++D + +G I +E+ Sbjct: 61 IIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGE 120 Query: 124 IVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 I+ A + V E+ + + DKN DG++ +EF Sbjct: 121 ILRATGEHV------------TEEDIEDLMKDSDKNNDGRIDFDEF 154 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 10/105 (9%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F++FDAD G I KE + + + ++L + D D +G I ++E L ++ Sbjct: 25 AFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMM-- 82 Query: 128 IYKMVGSMVKLPED-EDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + ++ ED + E+ + F + DKN DG + +EE E Sbjct: 83 -------VRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGE 120 Score = 32.7 bits (73), Expect = 0.096, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 32/60 (53%) Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 F +FD + +G+ID +E L T + + + D +N+G I +DE L++++ + Sbjct: 102 FRIFDKNADGFIDIEELGEILRATGEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMMEGV 161 >2HF5-A nrPDB Length = 68 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIV 125 + N DAD NG IDF EF+ ++ + +++ I AF+++D D NG IS E+ ++ Sbjct: 6 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM 64 >2JNX-A nrPDB Length = 134 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 19/108 (17%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDK---LIWAFQLYDLDNNGLISYDEML 122 + +F D D NG ID EF + +L+D+ L ++L D D +G ++ +E Sbjct: 39 QLIFKAIDIDGNGEIDLAEFTKFAAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEE-- 96 Query: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 V +K G EK V++I D N DG +TLEEF Sbjct: 97 --VTTFFKKFGY-----------EKVVDQIMK-ADANGDGYITLEEFL 130 >5MWC-D nrPDB Length = 311 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 32/60 (53%) Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 F FD D +G+ID +EF + +T ++ F D D NG I +DE L++V+ + Sbjct: 157 FRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFLKMVENV 216 Score = 28.1 bits (61), Expect = 2.7, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 8/66 (12%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYK---QFFPFGDPSAFAEYVFNVFDADKNGYI 80 ++EL + ++ F KD G +++ EF I + + DP + +F D DKNG I Sbjct: 150 EEELSECFRTFDKDG-DGFIDREEFGGIIRLTGEQLTDEDP----DEIFGDSDTDKNGRI 204 Query: 81 DFKEFI 86 DF EF+ Sbjct: 205 DFDEFL 210 Score = 27.7 bits (60), Expect = 3.2, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 12/84 (14%) Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTP 145 + A S+T+ ++L F+ +D D +G I +E I+ ++ G + DED Sbjct: 138 VMANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGII----RLTGEQLT---DEDPD 190 Query: 146 EKRVNKIFNMMDKNKDGQLTLEEF 169 E IF D +K+G++ +EF Sbjct: 191 E-----IFGDSDTDKNGRIDFDEF 209 >1JF0-A nrPDB Length = 195 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 32/131 (24%), Positives = 58/131 (44%), Gaps = 14/131 (10%) Query: 6 SKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF---------- 55 SK S D ++L +T + Q + FF+ C + +++F + + + Sbjct: 44 SKASDDICKNL-GATPAQTQRHQDCVEAFFRGCGLEYGKETKFPEFLEGWKNLANADLAK 102 Query: 56 FPFGDPSAFAEY---VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDN 112 + +P+ E+ VF++FD D +G I E+ ++ + FQ DLDN Sbjct: 103 WARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGRISGISPSEEDCEKTFQHCDLDN 162 Query: 113 NGLISYDEMLR 123 +G + DEM R Sbjct: 163 SGELDVDEMTR 173 Score = 28.1 bits (61), Expect = 2.1, Method: Compositional matrix adjust. Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 2/43 (4%) Query: 136 VKLPEDEDTPE--KRVNKIFNMMDKNKDGQLTLEEFCEGSKRD 176 VKL D D P+ KR +F+ +D N +GQ+TL+E + D Sbjct: 7 VKLQTDFDNPKWIKRHKFMFDYLDINGNGQITLDEIVSKASDD 49 >5D43-A nrPDB Length = 178 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 30/148 (20%), Positives = 70/148 (47%), Gaps = 15/148 (10%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 K+E+++ + F D SG ++ E K+ + F + + + D + G I F Sbjct: 30 KQEVREAFDLFDSDG-SGTIDVKEL-KVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 Query: 84 EFICALSVT-SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDE 142 +F+ ++ + + ++++ AF+L+D D G IS+ + R+ + + E Sbjct: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL------------GE 135 Query: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 ++ + ++ + D++ DG++ EEF Sbjct: 136 SLTDEELQEMIDEADRDGDGEVNEEEFL 163 >1OZS-A nrPDB Length = 73 Score = 35.8 bits (81), Expect = 0.010, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 30/61 (49%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 +F +FD + +GYID +E L T D + + D +N+G I YDE L + Sbjct: 12 LFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKG 71 Query: 128 I 128 + Sbjct: 72 V 72 >3E3R-A nrPDB Length = 204 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 6/108 (5%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 A AE V +D + +G +D +EF+ AL + AF D +G+++ D++ Sbjct: 73 AEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLR 132 Query: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN-KDGQLTLEEF 169 + + K+ E T ++ + + + D + KDGQ+TL EF Sbjct: 133 GVYSGR-----AHPKVRSGEWTEDEVLRRFLDNFDSSEKDGQVTLAEF 175 >2GGM-A nrPDB Length = 172 Score = 35.8 bits (81), Expect = 0.012, Method: Compositional matrix adjust. Identities = 35/168 (20%), Positives = 80/168 (47%), Gaps = 22/168 (13%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 T K+E+++ + F D +G ++ E K+ + F + + + D + G Sbjct: 26 TEEQKQEIREAFDLFDADG-TGTIDVKEL-KVAMRALGFEPKKEEIKKMISEIDKEGTGK 83 Query: 80 IDFKEFICALSVT-SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKL 138 ++F +F+ ++ S + ++++ AF+L+D D G IS+ + R+ K +G Sbjct: 84 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVA----KELG----- 134 Query: 139 PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLY 186 E+ ++ + ++ + D++ DG+++ +EF I+ SLY Sbjct: 135 ---ENLTDEELQEMIDEADRDGDGEVSEQEFL-------RIMKKTSLY 172 >2M5E-A nrPDB Length = 73 Score = 35.0 bits (79), Expect = 0.018, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 12/72 (16%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 ++LI AF+++D D NGLIS E+ ++ + + KL +DE V+++ D Sbjct: 8 EELIEAFKVFDRDGNGLISAAELRHVMTNLGE------KLTDDE------VDEMIREADI 55 Query: 159 NKDGQLTLEEFC 170 + DG + EEF Sbjct: 56 DGDGHINYEEFV 67 Score = 32.7 bits (73), Expect = 0.10, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 30/58 (51%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F VFD D NG I E ++ +D++ + D+D +G I+Y+E +R++ Sbjct: 13 AFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMM 70 >5Z1Q-A nrPDB Length = 95 Score = 35.0 bits (79), Expect = 0.019, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 29/58 (50%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F++FD +K G ID+ E A+ +++ YD + NG I +D+ L I+ Sbjct: 32 AFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDFLDIM 89 >2OBH-A nrPDB Length = 143 Score = 35.0 bits (79), Expect = 0.020, Method: Compositional matrix adjust. Identities = 31/152 (20%), Positives = 75/152 (49%), Gaps = 15/152 (9%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 T K+E+++ + F D +G ++ E K+ + F + + + D + G Sbjct: 1 TEEQKQEIREAFDLFDADG-TGTIDVKEL-KVAMRALGFEPKKEEIKKMISEIDKEGTGK 58 Query: 80 IDFKEFICALSVT-SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKL 138 ++F +F+ ++ S + ++++ AF+L+D D G IS+ + R+ K +G Sbjct: 59 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVA----KELG----- 109 Query: 139 PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 E+ ++ + ++ + D++ DG+++ +EF Sbjct: 110 ---ENLTDEELQEMIDEADRDGDGEVSEQEFL 138 >4NQG-A nrPDB Length = 197 Score = 34.7 bits (78), Expect = 0.023, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 8/64 (12%) Query: 64 FAEYVFNVFDADKNGYIDFKEFI----CALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 + + +F++ D D NG + E+I CA SRG+ F DLD +G + D Sbjct: 115 WGDALFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEA----TFAHCDLDGDGKLDVD 170 Query: 120 EMLR 123 EM R Sbjct: 171 EMTR 174 Score = 28.5 bits (62), Expect = 1.9, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 2/36 (5%) Query: 136 VKLPEDEDTPE--KRVNKIFNMMDKNKDGQLTLEEF 169 VKL D D P+ R +FN +D N +GQ+ L E Sbjct: 8 VKLDTDFDNPKWIARHKHMFNFLDINSNGQINLNEM 43 Score = 26.9 bits (58), Expect = 5.3, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 4/72 (5%) Query: 105 FQLYDLDNNGLISYDEML-RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 F D+++NG I+ +EM+ + + I K +G+ E +K V F D Sbjct: 27 FNFLDINSNGQINLNEMVHKASNIICKKLGAT---EEQTRRHQKCVEDFFGGAGLEYDKD 83 Query: 164 LTLEEFCEGSKR 175 T E+ EG KR Sbjct: 84 TTWPEYIEGWKR 95 >5E37-A nrPDB Length = 356 Score = 34.7 bits (78), Expect = 0.023, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 9/69 (13%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGEL---------NDKLIWAFQLYDLDNNGLI 116 E F + D D NG+ID +E L GE+ D+L + YD++ +G+I Sbjct: 32 ERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVNKDGVI 91 Query: 117 SYDEMLRIV 125 S++E +I+ Sbjct: 92 SFEEFKQII 100 Score = 33.9 bits (76), Expect = 0.043, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 13/70 (18%) Query: 105 FQLYDLDNNGLISYDEMLRIVDA-----IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 F++ D+D NG I +E+ ++++ +Y M S LPEDE + + D N Sbjct: 35 FKMADVDGNGHIDREELRNLLESMESGEVYMM--SQHWLPEDE------LERCMEQYDVN 86 Query: 160 KDGQLTLEEF 169 KDG ++ EEF Sbjct: 87 KDGVISFEEF 96 Score = 30.0 bits (66), Expect = 0.68, Method: Compositional matrix adjust. Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 25/141 (17%) Query: 40 SGHLNKSEFQKIYKQFFPFGD---------PSAFAEYVFNVFDADKNGYIDFKEF--ICA 88 +GH+++ E + + + G+ P E +D +K+G I F+EF I Sbjct: 43 NGHIDREELRNLLESM-ESGEVYMMSQHWLPEDELERCMEQYDVNKDGVISFEEFKQIIY 101 Query: 89 LSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKR 148 + G L + AF+ D NG I E+ + ++ +G+ V L EK Sbjct: 102 DGLLLEGTLAE-YESAFKAVDKSGNGTIGATELSK----LFASLGNPVSL-------EKL 149 Query: 149 VNKIFNMMDKNKDGQLTLEEF 169 V+ + M DK+ GQ+ EF Sbjct: 150 VD-LMQMYDKDDSGQIEFPEF 169 Score = 28.1 bits (61), Expect = 2.5, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 33/82 (40%) Query: 41 GHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDK 100 G ++ EF++I A E F D NG I E + +K Sbjct: 89 GVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASLGNPVSLEK 148 Query: 101 LIWAFQLYDLDNNGLISYDEML 122 L+ Q+YD D++G I + E L Sbjct: 149 LVDLMQMYDKDDSGQIEFPEFL 170 >1JFJ-A nrPDB Length = 134 Score = 34.7 bits (78), Expect = 0.023, Method: Compositional matrix adjust. Identities = 33/109 (30%), Positives = 49/109 (44%), Gaps = 19/109 (17%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW---AFQLYDLDNNGLISYDEML 122 + +F DAD NG ID EF +L+D I ++L D+D +G ++ +E Sbjct: 39 QLIFKSIDADGNGEIDQNEFAKFYGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEE-- 96 Query: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 V + +K G EK ++ D N DG +TLEEF E Sbjct: 97 --VTSFFKKHG-----------IEKVAEQVMK-ADANGDGYITLEEFLE 131 >3KPX-A nrPDB Length = 198 Score = 34.7 bits (78), Expect = 0.027, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 31/60 (51%) Query: 64 FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 + E VF++FD D +G I E+ ++ ++ F+ DLDN+G + DEM R Sbjct: 117 WGEAVFDIFDKDGSGSISLDEWKTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEMTR 176 >1S36-A nrPDB Length = 195 Score = 34.3 bits (77), Expect = 0.034, Method: Compositional matrix adjust. Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 14/131 (10%) Query: 6 SKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF---------- 55 SK S D L +T K Q + FF+ C + + F + F Sbjct: 44 SKASDDICAKL-EATPEQTKRHQVCVEAFFRGCGMEYGKEIAFPQFLDGFKQLATSELKK 102 Query: 56 FPFGDPSAFAEY---VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDN 112 + +P+ E+ VF++FD D +G I E+ ++ + F+ DLDN Sbjct: 103 WARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDLDN 162 Query: 113 NGLISYDEMLR 123 +G + DEM R Sbjct: 163 SGDLDVDEMTR 173 >4MVF-A nrPDB Length = 506 Score = 34.3 bits (77), Expect = 0.037, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 16/105 (15%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKL-IWAFQLYDLDNNGLISYDEMLRIVD 126 V D++ +G I + +F+ A ++ + L ++ + F+ +D+D NG IS +E+ RI Sbjct: 401 VLRDIDSNASGQIHYTDFLAA-TIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFG 459 Query: 127 AIYKMVGSMVKLPEDEDTP--EKRVNKIFNMMDKNKDGQLTLEEF 169 +D + P +K ++ + +D N DG++ EF Sbjct: 460 R------------DDIENPLIDKAIDSLLQEVDLNGDGEIDFHEF 492 >3PM8-A nrPDB Length = 197 Score = 33.9 bits (76), Expect = 0.042, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 16/105 (15%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKL-IWAFQLYDLDNNGLISYDEMLRIVD 126 V D++ +G I + +F+ A ++ + L ++ + F+ +D+D NG IS +E+ RI Sbjct: 98 VLRDIDSNASGQIHYTDFLAA-TIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFG 156 Query: 127 AIYKMVGSMVKLPEDEDTP--EKRVNKIFNMMDKNKDGQLTLEEF 169 +D + P +K ++ + +D N DG++ EF Sbjct: 157 R------------DDIENPLIDKAIDSLLQEVDLNGDGEIDFHEF 189 >3JAX-C nrPDB Length = 151 Score = 33.9 bits (76), Expect = 0.043, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 16/86 (18%) Query: 52 YKQFFPF-------GDPSAFAEYV--FNVFDADKNGYI---DFKEFICALSVTSRGELND 99 ++QF P D F +YV VFD + NG + + + + L E + Sbjct: 67 FEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVE 126 Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIV 125 +L+ + D+NG I+Y+E++R+V Sbjct: 127 QLVAGHE----DSNGCINYEELVRMV 148 >2JOJ-A nrPDB Length = 77 Score = 33.9 bits (76), Expect = 0.044, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 29/58 (50%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F++FD +K G ID+ E A+ +++ YD + NG I +D+ L I+ Sbjct: 12 AFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDFLDIM 69 >2B1U-A nrPDB Length = 71 Score = 33.5 bits (75), Expect = 0.055, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 13/78 (16%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 +R L D L AF+ +D D +G I+ DE+ R M G LP++E ++ + Sbjct: 1 ARAGLED-LQVAFRAFDQDGDGHITVDELRR------AMAGLGQPLPQEE------LDAM 47 Query: 153 FNMMDKNKDGQLTLEEFC 170 D ++DG++ EEF Sbjct: 48 IREADVDQDGRVNYEEFA 65 Score = 31.2 bits (69), Expect = 0.28, Method: Compositional matrix adjust. Identities = 15/60 (25%), Positives = 31/60 (51%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 + F FD D +G+I E A++ + ++L + D+D +G ++Y+E R++ Sbjct: 9 QVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARML 68 >2PMY-A nrPDB Length = 91 Score = 33.5 bits (75), Expect = 0.060, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 7/66 (10%) Query: 23 DKKELQQWYKGFFKDC---PSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 D +EL + + F C SG L + EF+ + + A AE VF DAD++G Sbjct: 22 DGEELARL-RSVFAACDANRSGRLEREEFRALCTELRV---RPADAEAVFQRLDADRDGA 77 Query: 80 IDFKEF 85 I F+EF Sbjct: 78 ITFQEF 83 Score = 27.3 bits (59), Expect = 3.7, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%) Query: 59 GDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISY 118 G+ A VF DA+++G ++ +EF AL R D FQ D D +G I++ Sbjct: 23 GEELARLRSVFAACDANRSGRLEREEFR-ALCTELRVRPADAEA-VFQRLDADRDGAITF 80 Query: 119 DEMLR 123 E R Sbjct: 81 QEFAR 85 >2JNF-A nrPDB Length = 158 Score = 33.5 bits (75), Expect = 0.064, Method: Compositional matrix adjust. Identities = 34/132 (25%), Positives = 53/132 (40%), Gaps = 34/132 (25%) Query: 44 NKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELN----- 98 KS +++ +F PFG NG IDF F + E+N Sbjct: 48 TKSTIRQLIDEFDPFG-----------------NGDIDFDSFKIIGARFLGEEVNPEQMQ 90 Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 +L AF+LYD + NG IS D M I+ + DE + ++ + + +D Sbjct: 91 QELREAFRLYDKEGNGYISTDVMREILAEL------------DETLSSEDLDAMIDEIDA 138 Query: 159 NKDGQLTLEEFC 170 + G + EEF Sbjct: 139 DGSGTVDFEEFM 150 >1C7W-A nrPDB Length = 81 Score = 33.1 bits (74), Expect = 0.066, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLI-WAFQLYDLDNNGLISYDEMLRIV 125 F VFDA+ +G IDF EF + L D + A + D D NG+I E + ++ Sbjct: 13 AFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEFMDLI 71 >1JC2-A nrPDB Length = 76 Score = 33.1 bits (74), Expect = 0.070, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 33/60 (55%) Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 F +FD + +G+ID +E L T + + + + D +N+G I +DE L++++ + Sbjct: 16 FRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFDEFLKMMEGV 75 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 12/77 (15%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 ++G+ ++L F+++D + +G I +E+ I+ A + V E+ + + Sbjct: 4 AKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHV------------IEEDIEDL 51 Query: 153 FNMMDKNKDGQLTLEEF 169 DKN DG++ +EF Sbjct: 52 MKDSDKNNDGRIDFDEF 68 >2LAP-A nrPDB Length = 167 Score = 33.1 bits (74), Expect = 0.079, Method: Compositional matrix adjust. Identities = 37/158 (23%), Positives = 72/158 (45%), Gaps = 19/158 (12%) Query: 18 RSTRFDK-KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 RS R ++ +EL++ ++ F KD G++N + + E + + + Sbjct: 17 RSLRPEEIEELREAFREFDKD-KDGYINCRDLGNCMRTMGYMPTEMELIELSQQI-NMNL 74 Query: 77 NGYIDFKEFICALSVTSRGELND-----KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 G++DF +F+ + E D +L AF+ +D + +G IS E + +A+ K+ Sbjct: 75 GGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSE---LREAMRKL 131 Query: 132 VGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 +G V + + +I +D N DG++ EEF Sbjct: 132 LGHQVG--------HRDIEEIIRDVDLNGDGRVDFEEF 161 Score = 29.6 bits (65), Expect = 0.92, Method: Compositional matrix adjust. Identities = 23/109 (21%), Positives = 46/109 (42%), Gaps = 9/109 (8%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F FD DK+GYI+ ++ + +LI Q +++ G + +D+ + ++ Sbjct: 30 AFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGP 89 Query: 128 -IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + M+ + E D F D N DG+++ E E ++ Sbjct: 90 KLLAETADMIGVKELRDA--------FREFDTNGDGEISTSELREAMRK 130 >2KN2-A nrPDB Length = 92 Score = 33.1 bits (74), Expect = 0.083, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 31/58 (53%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F VFD D+NGYI E + ++++ + DLD +G ++Y+E ++++ Sbjct: 14 AFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMM 71 Score = 30.4 bits (67), Expect = 0.53, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 12/72 (16%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 ++L AF+++D D NG IS E+ + M+ KL ++E V ++ D Sbjct: 9 EELKEAFKVFDKDQNGYISASELRHV------MINLGEKLTDEE------VEQMIKEADL 56 Query: 159 NKDGQLTLEEFC 170 + DGQ+ EEF Sbjct: 57 DGDGQVNYEEFV 68 >2ROB-A nrPDB Length = 70 Score = 32.7 bits (73), Expect = 0.086, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 31/58 (53%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F VFD D+NGYI E + ++++ + DLD +G ++Y+E ++++ Sbjct: 9 AFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMM 66 Score = 30.0 bits (66), Expect = 0.65, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 12/72 (16%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 ++L AF+++D D NG IS E+ + M+ KL ++E V ++ D Sbjct: 4 EELKEAFKVFDKDQNGYISASELRHV------MINLGEKLTDEE------VEQMIKEADL 51 Query: 159 NKDGQLTLEEFC 170 + DGQ+ EEF Sbjct: 52 DGDGQVNYEEFV 63 >2NCO-A nrPDB Length = 102 Score = 32.7 bits (73), Expect = 0.087, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 5/65 (7%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F+ YD D +G + DE+ ++ Y +G P ED V M D N DG + Sbjct: 21 FKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKED-----VKIWLQMADTNSDGSV 75 Query: 165 TLEEF 169 +LEE+ Sbjct: 76 SLEEY 80 >5PAL-A nrPDB Length = 109 Score = 32.7 bits (73), Expect = 0.093, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 7/81 (8%) Query: 52 YKQFFPF----GDPSAFAEYVFNVFDADKNGYIDFKEFICAL-SVTSRG-ELNDKLIWA- 104 YK+FF G A + VF + D D++G+I+ +E L ++ G +LND A Sbjct: 26 YKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKAL 85 Query: 105 FQLYDLDNNGLISYDEMLRIV 125 D D++G I DE ++V Sbjct: 86 LAAGDSDHDGKIGADEFAKMV 106 >1FW4-A nrPDB Length = 71 Score = 32.7 bits (73), Expect = 0.098, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 32/60 (53%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D NGYI E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 11 AFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 70 Score = 29.3 bits (64), Expect = 0.94, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 12/68 (17%) Query: 104 AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 AF+++D D NG IS E+ + M KL ++E V+++ D + DGQ Sbjct: 11 AFRVFDKDGNGYISAAELRHV------MTNLGEKLTDEE------VDEMIREADIDGDGQ 58 Query: 164 LTLEEFCE 171 + EEF + Sbjct: 59 VNYEEFVQ 66 >1Y1X-A nrPDB Length = 191 Score = 32.7 bits (73), Expect = 0.11, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 12/72 (16%) Query: 98 NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMD 157 N +L+ F+ D D +G IS E+ +A G L E K+ +M D Sbjct: 26 NQELMEWFRAVDTDGSGAISVPEL----NAALSSAGVPFSLATTE--------KLLHMYD 73 Query: 158 KNKDGQLTLEEF 169 KN G++T +EF Sbjct: 74 KNHSGEITFDEF 85 >2RO9-A nrPDB Length = 69 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 33/60 (55%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F VFD D+NG+I E ++ ++++ + D+D +G I+Y+E ++++ A Sbjct: 9 AFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMMA 68 Score = 30.4 bits (67), Expect = 0.45, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 12/72 (16%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 ++L AF+++D D NG IS E+ + M KL ++E V+++ D Sbjct: 4 EELKEAFRVFDKDQNGFISAAELRHV------MTNLGEKLTDEE------VDEMIREADV 51 Query: 159 NKDGQLTLEEFC 170 + DGQ+ EEF Sbjct: 52 DGDGQINYEEFV 63 >2LC5-A nrPDB Length = 151 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 32/127 (25%), Positives = 63/127 (49%), Gaps = 14/127 (11%) Query: 6 SKLSQDQLQDLVRSTRFD--KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSA 63 +KL+ ++L ++R+ + K+++ + K + KD SG ++ F I ++ D + Sbjct: 29 NKLTAEELGTVMRALGANPTKQKISEIVKDYDKD-NSGKFDQETFLTIMLEYGQEVDSTE 87 Query: 64 FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDL-----DNNGLISY 118 + F +FD +KNGYI E L+ L +KL ++ DL GLI+ Sbjct: 88 DIKKAFEIFDKEKNGYISASELKHVLTT-----LGEKLTEQ-EVDDLLKEIGVEEGLINV 141 Query: 119 DEMLRIV 125 D+ ++++ Sbjct: 142 DDFVKLI 148 Score = 26.6 bits (57), Expect = 6.3, Method: Compositional matrix adjust. Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 11/102 (10%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F +FD D + + +E + K+ + YD DN+G + L I Sbjct: 19 AFQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKDNSGKFDQETFLTI--- 75 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 M++ ++ D+ E + K F + DK K+G ++ E Sbjct: 76 -------MLEYGQEVDSTE-DIKKAFEIFDKEKNGYISASEL 109 >2M29-A nrPDB Length = 171 Score = 32.0 bits (71), Expect = 0.16, Method: Compositional matrix adjust. Identities = 21/107 (19%), Positives = 47/107 (43%), Gaps = 9/107 (8%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F FD D++GYI ++E + +L+ Q + G + ++E + ++ Sbjct: 33 AFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELISP 92 Query: 128 -IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 + + M+ + E + F DK++DG++T+ E + + Sbjct: 93 KLREETAHMLGVRE--------LRIAFREFDKDRDGRITVAELRQAA 131 >4ZCV-A nrPDB Length = 165 Score = 32.0 bits (71), Expect = 0.17, Method: Compositional matrix adjust. Identities = 29/116 (25%), Positives = 56/116 (48%), Gaps = 14/116 (12%) Query: 9 SQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF-FPFGDPSAFAEY 67 S+D QD + TR+ + ++ ++ G ++ E Q+ + P G + E Sbjct: 2 SEDACQDAEQPTRY-----ETLFQALDRNG-DGVVDIGELQEGLRNLGIPLGQDAE--EK 53 Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 +F D +K+G +DF+EF+ L + K+ AF+ D +N+G I E+++ Sbjct: 54 IFTTGDVNKDGKLDFEEFMKYLKDHEK-----KMKLAFKSLDKNNDGKIEASEIVQ 104 Score = 26.6 bits (57), Expect = 7.5, Method: Compositional matrix adjust. Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 12/65 (18%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 FQ D + +G++ E+ + + +P +D EK IF D NKDG+L Sbjct: 19 FQALDRNGDGVVDIGELQEGL--------RNLGIPLGQDAEEK----IFTTGDVNKDGKL 66 Query: 165 TLEEF 169 EEF Sbjct: 67 DFEEF 71 >4P5X-A nrPDB Length = 315 Score = 32.0 bits (71), Expect = 0.17, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 58 FGDPSA---FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNG 114 + DP++ + + V D K+G I ++EF+ SV + I AFQL+D NG Sbjct: 51 YNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPD--SMFIVAFQLFDKSGNG 108 Query: 115 LISYDEMLRI 124 ++++ + I Sbjct: 109 EVTFENVKEI 118 >6MI5-X nrPDB Length = 117 Score = 32.0 bits (71), Expect = 0.18, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 13/85 (15%) Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVT-------SRGELNDKLIWA------FQL 107 P+ + FD DK+G ID KE + A S G L+ K + + Sbjct: 1 PTTTTKVDIAAFDPDKDGTIDLKEALAAGSAAFDKLDPDKDGTLDAKELKGRVSEADLKK 60 Query: 108 YDLDNNGLISYDEMLRIVDAIYKMV 132 D DN+G + E L V+A +K Sbjct: 61 LDPDNDGTLDKKEYLAAVEAQFKAA 85 >5ZGM-A nrPDB Length = 110 Score = 32.0 bits (71), Expect = 0.18, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 7/81 (8%) Query: 52 YKQFFPF----GDPSAFAEYVFNVFDADKNGYIDFKEFICAL-SVTSRG-ELNDKLIWA- 104 YK+FF G A + VF + D D++G+I+ +E L ++ G +L+D A Sbjct: 27 YKRFFQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTETKAL 86 Query: 105 FQLYDLDNNGLISYDEMLRIV 125 D D++G I DE ++V Sbjct: 87 LAAGDSDHDGKIGADEFAKMV 107 >2LMV-A nrPDB Length = 148 Score = 31.6 bits (70), Expect = 0.21, Method: Compositional matrix adjust. Identities = 20/86 (23%), Positives = 39/86 (45%) Query: 40 SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND 99 +G LN +EF I + D F +FD D +G+I E + ++ Sbjct: 60 NGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEKVTDE 119 Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIV 125 ++ + D D +G+I+Y+E + ++ Sbjct: 120 EIDEMIREADFDGDGMINYEEFVWMI 145 >5ZH6-A nrPDB Length = 107 Score = 30.8 bits (68), Expect = 0.40, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 5/64 (7%) Query: 68 VFNVFDADKNGYIDFKE---FICALSVTSRGELNDKLIWAF-QLYDLDNNGLISYDEMLR 123 VF++ D D++G+I+ E F+ S T+R EL++ AF D D++G I DE Sbjct: 45 VFDILDQDRSGFIEVDELKLFLQNFSATAR-ELDETETNAFLAAGDSDHDGKIGVDEFKA 103 Query: 124 IVDA 127 +V A Sbjct: 104 MVKA 107 >5VE9-A nrPDB Length = 91 Score = 30.8 bits (68), Expect = 0.40, Method: Compositional matrix adjust. Identities = 12/23 (52%), Positives = 17/23 (73%) Query: 68 VFNVFDADKNGYIDFKEFICALS 90 V ++FD D +GYID+ EF+ AL Sbjct: 68 VADIFDRDGDGYIDYYEFVAALH 90 Score = 28.5 bits (62), Expect = 1.9, Method: Compositional matrix adjust. Identities = 11/27 (40%), Positives = 19/27 (70%) Query: 146 EKRVNKIFNMMDKNKDGQLTLEEFCEG 172 + RV F +DK++DG++T +EF +G Sbjct: 26 KSRVMDFFRRIDKDQDGKITRQEFIDG 52 >4N5X-A nrPDB Length = 199 Score = 30.8 bits (68), Expect = 0.41, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 8/84 (9%) Query: 41 GHLNKSEFQKIYKQF-FPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND 99 G ++ E Q+ + P G + E +F D +K+G +DF+EF+ L + Sbjct: 37 GVVDIGELQEGLRNLGIPLGQDAE--EKIFTTGDVNKDGKLDFEEFMKYLKDHEK----- 89 Query: 100 KLIWAFQLYDLDNNGLISYDEMLR 123 K+ AF+ D +N+G I E+++ Sbjct: 90 KMKLAFKSLDKNNDGKIEASEIVQ 113 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 12/89 (13%) Query: 82 FKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPED 141 ++F+ + + E + FQ D + +G++ E+ + + +P Sbjct: 5 LRDFVLPTAASQDAEQPTRYETLFQALDRNGDGVVDIGELQEGL--------RNLGIPLG 56 Query: 142 EDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 +D EK IF D NKDG+L EEF Sbjct: 57 QDAEEK----IFTTGDVNKDGKLDFEEFM 81 >1M39-A nrPDB Length = 89 Score = 30.4 bits (67), Expect = 0.44, Method: Compositional matrix adjust. Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 20/108 (18%) Query: 80 IDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKL 138 ++F +F+ ++ S + ++++ AF+L+D D G IS+ + R+ K +G Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVA----KELG----- 51 Query: 139 PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLY 186 E+ ++ + ++ + D++ DG+++ +EF I+ SLY Sbjct: 52 ---ENLTDEELQEMIDEADRDGDGEVSEQEFLR-------IMKKTSLY 89 Score = 27.3 bits (59), Expect = 4.3, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 32/83 (38%) Query: 43 LNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLI 102 +N +F + Q D F +FD D+ G I FK +++L Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQ 60 Query: 103 WAFQLYDLDNNGLISYDEMLRIV 125 D D +G +S E LRI+ Sbjct: 61 EMIDEADRDGDGEVSEQEFLRIM 83 >4L9M-A nrPDB Length = 559 Score = 30.4 bits (67), Expect = 0.44, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 19/87 (21%) Query: 57 PFGDPSAFAEYV-------FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYD 109 P DP +++V F +D D++GYI +EF ++ ++F + D Sbjct: 412 PKPDPKTISKHVQRMVDSVFKNYDHDQDGYISQEEF---------EKIAASFPFSFCVMD 462 Query: 110 LDNNGLISYDEMLRI---VDAIYKMVG 133 D GLIS DE+ +IY +G Sbjct: 463 KDREGLISRDEITAYFMRASSIYSKLG 489 >3A8R-A nrPDB Length = 179 Score = 30.4 bits (67), Expect = 0.47, Method: Compositional matrix adjust. Identities = 13/24 (54%), Positives = 17/24 (70%) Query: 148 RVNKIFNMMDKNKDGQLTLEEFCE 171 R+ F+M+DKN DG+LT EE E Sbjct: 99 RLRTFFDMVDKNADGRLTAEEVKE 122 >4WPX-A nrPDB Length = 177 Score = 30.4 bits (67), Expect = 0.49, Method: Compositional matrix adjust. Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 18/94 (19%) Query: 82 FKEFICALSVTSRGEL------NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 +++F A + G L D+L AF+L+D+D G+I+ D++ ++ + VG+ Sbjct: 88 YRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVC----QQVGNN 143 Query: 136 VKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 + P+ + + D N G + +EF Sbjct: 144 I--------PDADIQAMIEEFDSNGKGGVDEDEF 169 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 18/27 (66%) Query: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEF 169 D + R+++ F + D NKDG L+ EEF Sbjct: 22 DEQKTRISEAFELFDSNKDGLLSYEEF 48 Score = 26.2 bits (56), Expect = 9.4, Method: Compositional matrix adjust. Identities = 11/33 (33%), Positives = 22/33 (66%) Query: 96 ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 E ++ AF+L+D + +GL+SY+E ++ A+ Sbjct: 23 EQKTRISEAFELFDSNKDGLLSYEEFRFVLRAL 55 >4P5W-A nrPDB Length = 411 Score = 30.4 bits (67), Expect = 0.50, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 4/60 (6%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKL-IWAFQLYDLDNNGLISYDEMLRI 124 E + V D K+G I F+EF+ SV D L + AFQL+D G ++++++ ++ Sbjct: 81 ELLSGVVDQTKDGLISFQEFVAFESVLC---APDALFMVAFQLFDKAGKGEVTFEDVKQV 137 >2KGR-A nrPDB Length = 111 Score = 30.0 bits (66), Expect = 0.57, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 3/52 (5%) Query: 40 SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV 91 SGHL + + I Q P A ++N+ D D++G + +EFI A+ + Sbjct: 28 SGHLTGPQARTILMQS---SLPQAQLASIWNLSDIDQDGKLTAEEFILAMHL 76 Score = 29.6 bits (65), Expect = 0.85, Method: Compositional matrix adjust. Identities = 11/26 (42%), Positives = 19/26 (73%) Query: 145 PEKRVNKIFNMMDKNKDGQLTLEEFC 170 P+ ++ I+N+ D ++DG+LT EEF Sbjct: 46 PQAQLASIWNLSDIDQDGKLTAEEFI 71 >2KSZ-A nrPDB Length = 76 Score = 30.0 bits (66), Expect = 0.59, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 26/58 (44%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F +FD D +G I +E + + ++L D D NG I +DE L ++ Sbjct: 15 AFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLM 72 >1UHK-A nrPDB Length = 191 Score = 30.0 bits (66), Expect = 0.59, Method: Compositional matrix adjust. Identities = 15/60 (25%), Positives = 30/60 (50%) Query: 64 FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 + + +F++ D D+NG I E+ + ++ F++ D+D +G + DEM R Sbjct: 110 WGDALFDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 >6IIE-A nrPDB Length = 93 Score = 30.0 bits (66), Expect = 0.63, Method: Compositional matrix adjust. Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 12/91 (13%) Query: 95 GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPE--DEDTPEKR--VN 150 G DKL + F+LYD D NG++ E + K++ M+++ E D D E R + Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSE-------VDKIILQMMRVAEYLDWDVSELRPILQ 57 Query: 151 KIFNMMDKNKDGQLTLEEFCE-GSKRDPTIV 180 ++ +D + G ++ E+ G+ P +V Sbjct: 58 EMMKEIDYDGSGSVSQAEWVRAGATTVPLLV 88 Score = 26.9 bits (58), Expect = 5.6, Method: Compositional matrix adjust. Identities = 10/27 (37%), Positives = 15/27 (55%) Query: 59 GDPSAFAEYVFNVFDADKNGYIDFKEF 85 G P E+ F ++D D+NG +D E Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEV 31 >1SL8-A nrPDB Length = 191 Score = 30.0 bits (66), Expect = 0.69, Method: Compositional matrix adjust. Identities = 15/60 (25%), Positives = 30/60 (50%) Query: 64 FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 + + +F++ D D+NG I E+ + ++ F++ D+D +G + DEM R Sbjct: 110 WGDALFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 Score = 28.1 bits (61), Expect = 2.7, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 2/71 (2%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F D+++NG IS DEM+ I ++ ++ PE + V F + Sbjct: 22 FNFLDVNHNGRISLDEMVYKASDI--VINNLGATPEQAKRHKDAVEAFFGGAGMKYGVET 79 Query: 165 TLEEFCEGSKR 175 E+ EG KR Sbjct: 80 EWPEYIEGWKR 90 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Query: 136 VKLPEDEDTPE--KRVNKIFNMMDKNKDGQLTLEEF 169 VKL D D P+ R +FN +D N +G+++L+E Sbjct: 3 VKLTPDFDNPKWIGRHKHMFNFLDVNHNGRISLDEM 38 >3I5H-B nrPDB Length = 153 Score = 29.6 bits (65), Expect = 0.73, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 23/48 (47%), Gaps = 1/48 (2%) Query: 33 GFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYI 80 K+CP G LN + F ++ + DP F++FD D G+I Sbjct: 56 AMLKECP-GQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFI 102 >1F55-A nrPDB Length = 77 Score = 29.6 bits (65), Expect = 0.79, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 12/67 (17%) Query: 104 AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 AF L+D DNNG IS E+ ++ ++ E VN + N +D + + Q Sbjct: 15 AFALFDKDNNGSISSSELATVMRSLGL------------SPSEAEVNDLMNEIDVDGNHQ 62 Query: 164 LTLEEFC 170 + EF Sbjct: 63 IEFSEFL 69 >1OQP-A nrPDB Length = 77 Score = 29.6 bits (65), Expect = 0.88, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 39/72 (54%), Gaps = 12/72 (16%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 ++++ AF+L+D DN+G I+ ++ R+ K +G E+ E+ + ++ D+ Sbjct: 9 EEILKAFRLFDDDNSGTITIKDLRRVA----KELG--------ENLTEEELQEMIAEADR 56 Query: 159 NKDGQLTLEEFC 170 N D ++ +EF Sbjct: 57 NDDNEIDEDEFI 68 >2K2I-A nrPDB Length = 79 Score = 29.6 bits (65), Expect = 0.90, Method: Compositional matrix adjust. Identities = 22/94 (23%), Positives = 47/94 (50%), Gaps = 19/94 (20%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 S + ++++ AF+L+D D G IS+ + R+ K +G E+ ++ + ++ Sbjct: 5 SEKDTKEEILKAFKLFDDDETGKISFKNLKRVA----KELG--------ENLTDEELQEM 52 Query: 153 FNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLY 186 + D++ DG+++ +EF I+ SLY Sbjct: 53 IDEADRDGDGEVSEQEFL-------RIMKKTSLY 79 Score = 28.1 bits (61), Expect = 2.6, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 25/58 (43%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F +FD D+ G I FK +++L D D +G +S E LRI+ Sbjct: 16 AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIM 73 >2KZ2-A nrPDB Length = 94 Score = 29.3 bits (64), Expect = 1.0, Method: Compositional matrix adjust. Identities = 15/60 (25%), Positives = 31/60 (51%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F V D D NGYI E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 34 AFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 93 Score = 27.3 bits (59), Expect = 4.4, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 12/68 (17%) Query: 104 AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 AF++ D D NG IS E+ + M KL ++E V+++ D + DGQ Sbjct: 34 AFRVEDKDGNGYISAAELRHV------MTNLGEKLTDEE------VDEMIREADIDGDGQ 81 Query: 164 LTLEEFCE 171 + EEF + Sbjct: 82 VNYEEFVQ 89 >4NSC-A nrPDB Length = 401 Score = 29.3 bits (64), Expect = 1.2, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 27/63 (42%), Gaps = 14/63 (22%) Query: 107 LYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTL 166 Y L GLIS+ + + + + TP++ F M D N DG++ + Sbjct: 120 FYTLGECGLISFSDYIFLTTVL--------------STPQRNFEIAFKMFDLNGDGEVDM 165 Query: 167 EEF 169 EEF Sbjct: 166 EEF 168 Score = 26.2 bits (56), Expect = 9.4, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 3/67 (4%) Query: 78 GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 G I F ++I +V S + N ++ AF+++DL+ +G + +E + V +I + SM Sbjct: 127 GLISFSDYIFLTTVLSTPQRNFEI--AFKMFDLNGDGEVDMEEFEQ-VQSIIRSQTSMGM 183 Query: 138 LPEDEDT 144 D T Sbjct: 184 RHRDRPT 190 >2N7L-C nrPDB Length = 141 Score = 29.3 bits (64), Expect = 1.2, Method: Compositional matrix adjust. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 T K E + + F G ++ E K+ + P E + V D D +G Sbjct: 28 TEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEV-DEDGSGT 86 Query: 80 IDFKEFICAL 89 +DF EF+ + Sbjct: 87 VDFDEFLVMM 96 >2Q4U-A nrPDB Length = 272 Score = 29.3 bits (64), Expect = 1.2, Method: Compositional matrix adjust. Identities = 34/159 (21%), Positives = 60/159 (37%), Gaps = 25/159 (15%) Query: 40 SGHLNKSEFQKIYKQFF-------PFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV- 91 SG+++ +E + K F P + + + +FD +K+G +D + L++ Sbjct: 118 SGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQ 177 Query: 92 -----------TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPE 140 +S+ E F YD+ G + E VD K + +V+ Sbjct: 178 ENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPE----VDGFVKDMMELVRPSI 233 Query: 141 DEDTPEKRVNKIFNMMDKNKDGQLTLEE--FCEGSKRDP 177 +K + D NKDG++ E C G K P Sbjct: 234 SGGDLDKFRECLLTHCDMNKDGKIQKSELALCLGLKHKP 272 Score = 26.6 bits (57), Expect = 6.5, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 37/69 (53%), Gaps = 6/69 (8%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 IW + YD D++G IS E+ + ++ + K+P ++ ++ + + + DKNKD Sbjct: 109 IW--RKYDADSSGYISAAELKNFLKDLF--LQHKKKIPPNK--LDEYTDAMMKIFDKNKD 162 Query: 162 GQLTLEEFC 170 G+L L + Sbjct: 163 GRLDLNDLA 171 >1TIZ-A nrPDB Length = 67 Score = 28.9 bits (63), Expect = 1.3, Method: Compositional matrix adjust. Identities = 12/21 (57%), Positives = 17/21 (80%) Query: 151 KIFNMMDKNKDGQLTLEEFCE 171 ++F DKNKDG+L+L+EF E Sbjct: 5 RVFEKFDKNKDGKLSLDEFRE 25 Score = 27.3 bits (59), Expect = 4.0, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 31/64 (48%) Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 A+ VF FD +K+G + EF S + ++ F+ D+D NG ++ DE Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTSC 62 Query: 125 VDAI 128 ++ + Sbjct: 63 IEKM 66 >1FI6-A nrPDB Length = 92 Score = 28.9 bits (63), Expect = 1.4, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 145 PEKRVNKIFNMMDKNKDGQLTLEEFCEG 172 P ++ I+ + D +KDG LTL+EFC Sbjct: 41 PILELSHIWELSDFDKDGALTLDEFCAA 68 >2LV7-A nrPDB Length = 100 Score = 28.9 bits (63), Expect = 1.4, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 12/67 (17%) Query: 104 AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 AF+++D D NG IS E+ + +G M E + I +D + DGQ Sbjct: 41 AFKVFDRDGNGFISKQEL----GTAMRSLGYMPN--------EVELEVIIQRLDMDGDGQ 88 Query: 164 LTLEEFC 170 + EEF Sbjct: 89 VDFEEFV 95 Score = 26.2 bits (56), Expect = 9.1, Method: Compositional matrix adjust. Identities = 16/66 (24%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 +E+++ +K F +D +G ++K E + + E + D D +G +DF+E Sbjct: 36 EEIREAFKVFDRDG-NGFISKQELGTAMRSLG-YMPNEVELEVIIQRLDMDGDGQVDFEE 93 Query: 85 FICALS 90 F+ L Sbjct: 94 FVTLLG 99 >4GJF-A nrPDB Length = 89 Score = 28.9 bits (63), Expect = 1.5, Method: Compositional matrix adjust. Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 T K E + + F + G ++ E K+ + P E + V D D +G Sbjct: 13 TEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEV-DEDGSGT 71 Query: 80 IDFKEFICAL 89 +DF EF+ + Sbjct: 72 VDFDEFLVMM 81 >5VLN-A nrPDB Length = 120 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 T K E + + F G ++ E K+ + P E + V D D +G Sbjct: 13 TEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEV-DEDGSGT 71 Query: 80 IDFKEFICAL 89 +DF EF+ + Sbjct: 72 VDFDEFLVMM 81 >2K7C-A nrPDB Length = 72 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 11/67 (16%) Query: 104 AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 AF+ +D + +G IS E+ +A+ K++G V + + +I +D N DG+ Sbjct: 12 AFREFDTNGDGEISTSELR---EAMRKLLGHQV--------GHRDIEEIIRDVDLNGDGR 60 Query: 164 LTLEEFC 170 + EEF Sbjct: 61 VDFEEFV 67 >3I5I-C nrPDB Length = 159 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 12/73 (16%) Query: 89 LSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKR 148 +S G D+ + AF+ +D + GLIS E+ ++ KM+G + E + Sbjct: 75 MSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVL----KMLGERI--------TEDQ 122 Query: 149 VNKIFNMMDKNKD 161 N IF D +D Sbjct: 123 CNDIFTFCDIRED 135 >2K2A-A nrPDB Length = 70 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 12/73 (16%) Query: 97 LNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMM 156 + +L AF+LYD + NG IS D M I+ + DE + ++ + + + Sbjct: 1 MQQELREAFRLYDKEGNGYISTDVMREILAEL------------DETLSSEDLDAMIDEI 48 Query: 157 DKNKDGQLTLEEF 169 D + G + EEF Sbjct: 49 DADGSGTVDFEEF 61 >5JOJ-A nrPDB Length = 97 Score = 28.5 bits (62), Expect = 1.8, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 10/64 (15%) Query: 68 VFNVFDADKNGYIDFKEF-------ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 F D D NGYI F E L E+ + L+ DLD +G IS+DE Sbjct: 17 AFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT---GDLDQDGRISFDE 73 Query: 121 MLRI 124 ++I Sbjct: 74 FIKI 77 Score = 28.1 bits (61), Expect = 2.7, Method: Compositional matrix adjust. Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 20/85 (23%) Query: 93 SRGELNDK----LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKR 148 +RG ++D+ L AF D D NG IS++E+ + A LP P R Sbjct: 2 ARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAAC--------LP----LPGYR 49 Query: 149 VNKIF-NMM---DKNKDGQLTLEEF 169 V +I N+M D ++DG+++ +EF Sbjct: 50 VREITENLMATGDLDQDGRISFDEF 74 >1BU3-A nrPDB Length = 109 Score = 28.5 bits (62), Expect = 1.8, Method: Compositional matrix adjust. Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 3/63 (4%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRG--ELNDKLIWAF-QLYDLDNNGLISYDEMLRI 124 F V D DK+G+I+ E L V S G L D AF + D D +G I DE + Sbjct: 47 AFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAFLKAGDSDGDGAIGVDEWAAL 106 Query: 125 VDA 127 V A Sbjct: 107 VKA 109 >1RTP-1 nrPDB Length = 109 Score = 28.5 bits (62), Expect = 1.9, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 13/68 (19%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK--LPEDEDTPEKRVNKIFNMMDKNKDG 162 F + D D +G I DE+ GS++K + D K + DK+ DG Sbjct: 47 FHILDKDKSGFIEEDEL-----------GSILKGFSSDARDLSAKETKTLMAAGDKDGDG 95 Query: 163 QLTLEEFC 170 ++ +EEF Sbjct: 96 KIGVEEFS 103 >5JOL-A nrPDB Length = 82 Score = 28.5 bits (62), Expect = 2.0, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 10/68 (14%) Query: 68 VFNVFDADKNGYIDFKEF-------ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 F D D NGYI F E L E+ + L+ DLD +G IS+DE Sbjct: 17 AFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT---GDLDQDGRISFDE 73 Query: 121 MLRIVDAI 128 ++I + Sbjct: 74 FIKIFHGL 81 Score = 27.7 bits (60), Expect = 3.0, Method: Compositional matrix adjust. Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 20/85 (23%) Query: 93 SRGELNDK----LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKR 148 +RG ++D+ L AF D D NG IS++E+ + A LP P R Sbjct: 2 ARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKA--------ACLP----LPGYR 49 Query: 149 VNKIF-NMM---DKNKDGQLTLEEF 169 V +I N+M D ++DG+++ +EF Sbjct: 50 VREITENLMATGDLDQDGRISFDEF 74 >3IFK-A nrPDB Length = 90 Score = 28.5 bits (62), Expect = 2.0, Method: Compositional matrix adjust. Identities = 11/23 (47%), Positives = 15/23 (65%) Query: 68 VFNVFDADKNGYIDFKEFICALS 90 + N DAD NG IDF EF+ ++ Sbjct: 51 MINEVDADGNGTIDFPEFLTMMA 73 >2I08-A nrPDB Length = 78 Score = 28.1 bits (61), Expect = 2.1, Method: Compositional matrix adjust. Identities = 11/23 (47%), Positives = 15/23 (65%) Query: 68 VFNVFDADKNGYIDFKEFICALS 90 + N DAD NG IDF EF+ ++ Sbjct: 51 MINEVDADGNGTIDFPEFLTMMA 73 Score = 26.9 bits (58), Expect = 5.3, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 26/63 (41%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 F+++D D +G I KE + +L D D NG I + E L ++ Sbjct: 15 AFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 74 Query: 128 IYK 130 I K Sbjct: 75 IMK 77 >3J04-B nrPDB Length = 143 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 23/118 (19%), Positives = 50/118 (42%), Gaps = 3/118 (2%) Query: 8 LSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEY 67 + ++ L D++ S K ++ +G + P G +N + F ++ + DP Sbjct: 24 IDKEDLHDMLAS--MGKNPTDEYLEGMMSEAP-GPINFTMFLTMFGEKLNGTDPEDVIRN 80 Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 F FD + +G+I L+ ++++ ++ +D G +Y E RI+ Sbjct: 81 AFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRIL 138 >5H7D-E nrPDB Length = 120 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 11/23 (47%), Positives = 15/23 (65%) Query: 68 VFNVFDADKNGYIDFKEFICALS 90 + N DAD NG IDF EF+ ++ Sbjct: 97 MINEVDADGNGTIDFPEFLTMMA 119 >2VXO-A nrPDB Length = 697 Score = 28.1 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 21/36 (58%), Gaps = 2/36 (5%) Query: 122 LRIVDAIYKMVGSMVKLP-EDED-TPEKRVNKIFNM 155 +++++A + LP DED TP KR++K NM Sbjct: 298 VKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNM 333 >2G9B-A nrPDB Length = 263 Score = 28.1 bits (61), Expect = 2.5, Method: Compositional matrix adjust. Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 15/82 (18%) Query: 60 DPSAFAEY---VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW--------AFQLY 108 D + AEY + +FD++ +G ++ E L V L + I AF+LY Sbjct: 141 DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELY 200 Query: 109 DLDNNGLISYDEMLRIVDAIYK 130 D D NG I +E+ DA+ K Sbjct: 201 DQDGNGYIDENEL----DALLK 218 >4Q57-A nrPDB Length = 65 Score = 28.1 bits (61), Expect = 2.6, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 6/67 (8%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEY--VFNVFDADKNGYIDFK 83 E ++ + F KD G + E + + G AE + N DAD NG IDF Sbjct: 3 EFKEAFSLFDKDG-DGTITTKELGTVMRSL---GQNPTEAELQDMINEVDADGNGTIDFP 58 Query: 84 EFICALS 90 EF+ ++ Sbjct: 59 EFLTMMA 65 >1G33-A nrPDB Length = 73 Score = 28.1 bits (61), Expect = 2.6, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 13/68 (19%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK--LPEDEDTPEKRVNKIFNMMDKNKDG 162 F + D D +G I DE+ GS++K + D K + DK+ DG Sbjct: 11 FHILDKDKSGFIEEDEL-----------GSILKGFSSDARDLSAKETKTLMAAGDKDGDG 59 Query: 163 QLTLEEFC 170 ++ +EEF Sbjct: 60 KIGVEEFS 67 >2AMI-A nrPDB Length = 96 Score = 28.1 bits (61), Expect = 2.6, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Query: 10 QDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVF 69 +DQ + V T K+E+++ + F D SG ++ E K+ + F + + Sbjct: 15 RDQKKGRVGLTEEQKQEIREAFDLFDTDG-SGTIDAKEL-KVAMRALGFEPKKEEIKKMI 72 Query: 70 NVFDADKNGYIDFKEFICALSV 91 + D D +G IDF+EF+ ++ Sbjct: 73 SEIDKDGSGTIDFEEFLTMMTA 94 >1RK9-A nrPDB Length = 110 Score = 27.7 bits (60), Expect = 2.8, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 28/66 (42%), Gaps = 9/66 (13%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F + D D +G I DE+ I+ P+ D K + DK+ DG++ Sbjct: 48 FHMLDKDKSGFIEEDELGFILKGFS---------PDARDLSAKETKMLMAAGDKDGDGKI 98 Query: 165 TLEEFC 170 ++EF Sbjct: 99 GVDEFS 104 >4MSP-A nrPDB Length = 200 Score = 27.7 bits (60), Expect = 3.0, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 4/67 (5%) Query: 104 AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 +FQ DL+++ +S DE+ + ++ G++V +E + V IF+ D++KDG Sbjct: 132 SFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVV----NESHHDALVEDIFDKEDEDKDGF 187 Query: 164 LTLEEFC 170 ++ EF Sbjct: 188 ISAREFT 194 >3AAJ-A nrPDB Length = 167 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 33/130 (25%), Positives = 58/130 (44%), Gaps = 31/130 (23%) Query: 43 LNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALS-VTSRGELNDKL 101 +N SEF ++K + + VF +D D +G ID E ALS + +D L Sbjct: 58 VNFSEFTGVWKYITDW-------QNVFRTYDRDNSGMIDKNELKQALSGYRLSDQFHDIL 110 Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 I + +D G I++D+ ++ G +V +R+ IF D ++D Sbjct: 111 I---RKFDRQGRGQIAFDDFIQ---------GCIVL---------QRLTDIFRRYDTDQD 149 Query: 162 G--QLTLEEF 169 G Q++ E++ Sbjct: 150 GWIQVSYEQY 159 >4PAL-A nrPDB Length = 108 Score = 27.7 bits (60), Expect = 3.5, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 5/64 (7%) Query: 68 VFNVFDADKNGYI---DFKEFICALSVTSRGELNDKLIWAFQL-YDLDNNGLISYDEMLR 123 F V D DK+G+I + K F+ S ++R L D AF D D +G+I DE Sbjct: 46 AFYVIDQDKSGFIEEDELKLFLQNFSPSARA-LTDAETKAFLADGDKDGDGMIGVDEFAA 104 Query: 124 IVDA 127 ++ A Sbjct: 105 MIKA 108 >3PAT-A nrPDB Length = 110 Score = 27.7 bits (60), Expect = 3.5, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 7/81 (8%) Query: 52 YKQFFPFGDPSAFA----EYVFNVFDADKNGYIDFKEFICAL-SVTSRG-ELNDKLIWAF 105 +K+FF A + + VF DAD +G+I+ +E L S + G +L D AF Sbjct: 27 HKKFFALVGLKAMSANDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAF 86 Query: 106 -QLYDLDNNGLISYDEMLRIV 125 + D D +G I DE +V Sbjct: 87 LKAADKDGDGKIGIDEFETLV 107 >5COC-A nrPDB Length = 130 Score = 27.3 bits (59), Expect = 3.6, Method: Compositional matrix adjust. Identities = 11/23 (47%), Positives = 15/23 (65%) Query: 68 VFNVFDADKNGYIDFKEFICALS 90 + N DAD NG IDF EF+ ++ Sbjct: 104 MINEVDADGNGTIDFPEFLTMMA 126 >1IJ5-A nrPDB Length = 323 Score = 27.3 bits (59), Expect = 3.6, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Query: 40 SGHLNKSEFQKIYK-QFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFI 86 SG L+K E QK+ + P F E+ F+V D D + + ++EF+ Sbjct: 267 SGQLSKEEVQKVLEDAHIPESARKKF-EHQFSVVDVDDSKSLSYQEFV 313 >3LCP-C nrPDB Length = 93 Score = 27.3 bits (59), Expect = 3.9, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 30/66 (45%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F+++D D N L+ E+ + ++K GS ED ++ + DKN DG + Sbjct: 24 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 83 Query: 165 TLEEFC 170 EF Sbjct: 84 DYAEFA 89 >5FBH-B nrPDB Length = 568 Score = 27.3 bits (59), Expect = 3.9, Method: Compositional matrix adjust. Identities = 11/41 (26%), Positives = 22/41 (53%) Query: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSAL 183 +T K + + + +NK L L+EFC S+ P+ ++ + Sbjct: 129 NTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHIPSTIAVV 169 >6EAZ-A nrPDB Length = 379 Score = 27.3 bits (59), Expect = 4.1, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 73 DADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D G I + E++ L++ ++ + AF++ D+D N +I E +++ I K Sbjct: 95 DLGDKGVISYTEYLFLLTILTKPHSGFHV--AFKMLDVDGNEMIERKEFVKLQKIISKQD 152 Query: 133 G-SMVKLPEDE 142 G VK E E Sbjct: 153 GFKTVKTNETE 163 >2VRG-A nrPDB Length = 124 Score = 27.3 bits (59), Expect = 4.3, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 30/66 (45%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F+++D D N L+ E+ + ++K GS ED ++ + DKN DG + Sbjct: 55 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 114 Query: 165 TLEEFC 170 EF Sbjct: 115 DYAEFA 120 >1CB1-A nrPDB Length = 78 Score = 27.3 bits (59), Expect = 4.5, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 32/54 (59%), Gaps = 10/54 (18%) Query: 116 ISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 +S +E+ +++ A + S++K P + ++ +F +DKN DG+++ EEF Sbjct: 26 LSKEELKQLIQAEFP---SLLKGP-------RTLDDLFQELDKNGDGEVSFEEF 69 >3A4U-B nrPDB Length = 143 Score = 26.9 bits (58), Expect = 5.4, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 30/66 (45%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F+++D D N L+ E+ + ++K GS ED ++ + DKN DG + Sbjct: 74 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 133 Query: 165 TLEEFC 170 EF Sbjct: 134 DYAEFA 139 >2WCE-A nrPDB Length = 95 Score = 26.9 bits (58), Expect = 5.5, Method: Compositional matrix adjust. Identities = 15/64 (23%), Positives = 30/64 (46%), Gaps = 1/64 (1%) Query: 32 KGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV 91 KG F G L + +++ D + E +F DA+++ +DF+EFI +++ Sbjct: 25 KGHFDTLSKGELKQLLTKELANTIKNIKDKAVIDE-IFQGLDANQDEQVDFQEFISMVAI 83 Query: 92 TSRG 95 + Sbjct: 84 ALKA 87 >4YGB-B nrPDB Length = 104 Score = 26.9 bits (58), Expect = 5.5, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 30/66 (45%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F+++D D N L+ E+ + ++K GS ED ++ + DKN DG + Sbjct: 35 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 94 Query: 165 TLEEFC 170 EF Sbjct: 95 DYAEFA 100 >1YX7-A nrPDB Length = 83 Score = 26.9 bits (58), Expect = 5.6, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 12/72 (16%) Query: 101 LIWAFQLYDLDNNGLISYDEM---LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMD 157 L AF+ D + +G ++ E+ + +DA YK + +D ++ K+ M D Sbjct: 9 LEAAFKKLDANGDGYVTALELQTFMVTLDA-YKALS--------KDKVKEASAKLIKMAD 59 Query: 158 KNKDGQLTLEEF 169 KN DG+++ EEF Sbjct: 60 KNSDGKISKEEF 71 >1NYA-A nrPDB Length = 176 Score = 26.9 bits (58), Expect = 5.8, Method: Compositional matrix adjust. Identities = 11/22 (50%), Positives = 13/22 (59%) Query: 149 VNKIFNMMDKNKDGQLTLEEFC 170 V I M DKN DGQ+ +EF Sbjct: 104 VKGIVGMCDKNADGQINADEFA 125 Score = 26.9 bits (58), Expect = 6.0, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 9/92 (9%) Query: 41 GHLNKSEFQKIYKQF-FPFGDPS------AFAEYVFNVFDADKNGYIDFKEFICALSVTS 93 G L + +F ++ + F G+ S + + + D + +G I+ EF L T+ Sbjct: 73 GSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEFAAWL--TA 130 Query: 94 RGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 G + AF D + NG +S DE+L V Sbjct: 131 LGMSKAEAAEAFNQVDTNGNGELSLDELLTAV 162 >2LVV-A nrPDB Length = 226 Score = 26.9 bits (58), Expect = 5.9, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 21/45 (46%) Query: 43 LNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFIC 87 L EF++ + +G A VFN D + +G + F EF C Sbjct: 150 LELQEFKEALPKLKEWGVDITDATTVFNEIDTNGSGVVTFDEFSC 194 >6AGI-A nrPDB Length = 382 Score = 26.9 bits (58), Expect = 6.0, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 15/27 (55%) Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFIC 87 P A FN+FD D N +D KEF+ Sbjct: 103 PHAGFRIAFNMFDTDGNEMVDKKEFLV 129 Score = 26.6 bits (57), Expect = 6.5, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 8/41 (19%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLY 108 VF +FD DK+ + +KEFI G + D+L F+ Y Sbjct: 348 VFKIFDVDKDDQLSYKEFI--------GIMKDRLHRGFRGY 380 >2RO8-A nrPDB Length = 79 Score = 26.6 bits (57), Expect = 6.3, Method: Compositional matrix adjust. Identities = 11/19 (57%), Positives = 13/19 (68%) Query: 68 VFNVFDADKNGYIDFKEFI 86 + N DAD NG IDF EF+ Sbjct: 51 MINEVDADGNGTIDFPEFL 69 >3SIA-A nrPDB Length = 220 Score = 26.6 bits (57), Expect = 6.3, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 8/65 (12%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFG---DPSAFAEYVFNVFDADKNGYID 81 + QW+ G +D SG L E ++ FP G P A + +FD D NG+I Sbjct: 51 TRIYQWFMGVDRD-RSGTL---EINELMMGQFPGGIRLSPQT-ALRMMRIFDTDFNGHIS 105 Query: 82 FKEFI 86 F EF+ Sbjct: 106 FYEFM 110 >2MA2-A nrPDB Length = 81 Score = 26.6 bits (57), Expect = 6.4, Method: Compositional matrix adjust. Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 7/58 (12%) Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 E VF FD D +G+I +EF RG N + AF D + +G IS +EM+ Sbjct: 15 VESVFRNFDVDGDGHISQEEFQII-----RG--NFPYLSAFGDLDQNQDGCISREEMV 65 >3D3X-A nrPDB Length = 427 Score = 26.6 bits (57), Expect = 7.8, Method: Compositional matrix adjust. Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 3/38 (7%) Query: 140 EDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDP 177 E++D K V KIFN ++ N G + LEE SK +P Sbjct: 77 EEKDRFLKIVTKIFNRINNNLSGGILLEEL---SKANP 111 >4OKH-A nrPDB Length = 189 Score = 26.2 bits (56), Expect = 8.1, Method: Compositional matrix adjust. Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 6/43 (13%) Query: 74 ADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLI 116 ADK+ IDF FIC V G + AF +D D +G+I Sbjct: 131 ADKHMNIDFDSFICCF-VRLEG-----MFRAFHAFDKDGDGII 167 >5OTJ-D nrPDB Length = 110 Score = 26.2 bits (56), Expect = 9.1, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 10/40 (25%) Query: 72 FDADKNGYIDFKEFICALSVTS----------RGELNDKL 101 D D +G+IDF EFI + +GELN KL Sbjct: 47 IDTDGDGFIDFNEFISFCNANPGLMKDVAKVFKGELNSKL 86 >2YUF-A nrPDB Length = 142 Score = 26.2 bits (56), Expect = 9.1, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 5/55 (9%) Query: 120 EMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNK---IFNMMD-KNKDG-QLTLEEF 169 E+L+ + KM+G + ++ +D+ E+ + K I+ D K KDG LTL E Sbjct: 39 ELLKTNKKLAKMIGHIFEMNDDDPHKEEEIRKYSAIYGRFDSKRKDGKHLTLHEL 93 >2KQY-A nrPDB Length = 108 Score = 26.2 bits (56), Expect = 9.5, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 3/63 (4%) Query: 68 VFNVFDADKNGYIDFKE---FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 VF + D DK+G+I+ +E F+ S ++R + + D D +G I +E + Sbjct: 46 VFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAFLAAGDTDGDGKIGVEEFQSL 105 Query: 125 VDA 127 V A Sbjct: 106 VKA 108 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2L2E-A nrPDB 244 2e-65 2LCP-A nrPDB 231 1e-61 5T7C-A nrPDB 228 1e-60 1BJF-A nrPDB 227 2e-60 2JU0-A nrPDB 224 2e-59 5M6C-E nrPDB 222 6e-59 2JUL-A nrPDB 214 2e-56 6EPA-A nrPDB 206 4e-54 3DD4-A nrPDB 201 2e-52 1S6C-A nrPDB 201 2e-52 1S1E-A nrPDB 200 3e-52 2I94-A nrPDB 187 2e-48 2D8N-A nrPDB 178 1e-45 1JBA-A nrPDB 158 1e-39 2R2I-A nrPDB 157 2e-39 2NA0-A nrPDB 154 3e-38 3U0K-A nrPDB 153 5e-38 4IL1-A nrPDB 152 9e-38 4OY4-A nrPDB 151 2e-37 3EK4-A nrPDB 149 7e-37 5UKG-A nrPDB 145 1e-35 2GGZ-A nrPDB 143 4e-35 4I2Y-A nrPDB 142 1e-34 1V1G-A nrPDB 141 2e-34 2ZFD-A nrPDB 138 9e-34 3HZT-A nrPDB 138 1e-33 1UHN-A nrPDB 134 2e-32 3WFN-B nrPDB 134 2e-32 2N6A-A nrPDB 133 3e-32 5JN2-A nrPDB 130 3e-31 6O20-F nrPDB 130 3e-31 2F2P-A nrPDB 130 5e-31 2LM5-A nrPDB 129 7e-31 3LIJ-A nrPDB 129 7e-31 4E53-A nrPDB 127 2e-30 5YPX-A nrPDB 126 5e-30 6HCS-A nrPDB 125 1e-29 3KHE-A nrPDB 125 2e-29 4YZB-A nrPDB 122 9e-29 4RGJ-A nrPDB 122 1e-28 5I0I-E nrPDB 122 1e-28 4ORC-B nrPDB 121 2e-28 1CLM-A nrPDB 120 4e-28 1DGU-A nrPDB 120 5e-28 3L19-A nrPDB 119 6e-28 3Q5I-A nrPDB 118 9e-28 5A2H-A nrPDB 117 2e-27 5B8I-B nrPDB 117 4e-27 1GGZ-A nrPDB 115 1e-26 2E6W-A nrPDB 112 9e-26 3NCG-A nrPDB 109 6e-25 2E30-A nrPDB 109 6e-25 3QRX-A nrPDB 108 2e-24 2LHI-A nrPDB 104 2e-23 1DTL-A nrPDB 104 3e-23 2BEC-A nrPDB 103 4e-23 2L1W-A nrPDB 102 8e-23 4DS7-A nrPDB 102 1e-22 4JWQ-A nrPDB 100 7e-22 1TOP-A nrPDB 99 1e-21 1LKJ-A nrPDB 99 1e-21 3O4Y-A nrPDB 98 3e-21 2AAO-A nrPDB 98 3e-21 1S6I-A nrPDB 97 3e-21 2TN4-A nrPDB 97 5e-21 3KF9-A nrPDB 97 6e-21 3K21-A nrPDB 94 3e-20 2LHH-A nrPDB 90 4e-19 5ZOR-A nrPDB 89 1e-18 2BL0-C nrPDB 84 5e-17 2HF5-A nrPDB 80 5e-16 2HPS-A nrPDB 63 7e-11 2M97-A nrPDB 54 3e-08 Sequences not found previously or not previously below threshold: 2LMV-A nrPDB 94 4e-20 5D43-A nrPDB 93 7e-20 2GGM-A nrPDB 91 3e-19 4MVF-A nrPDB 90 5e-19 3PM8-A nrPDB 85 2e-17 2OBH-A nrPDB 85 2e-17 2LAP-A nrPDB 84 3e-17 2JNF-A nrPDB 78 2e-15 3E3R-A nrPDB 77 6e-15 3FWC-A nrPDB 76 8e-15 2M29-A nrPDB 75 1e-14 4WPX-A nrPDB 73 8e-14 5MWC-D nrPDB 72 2e-13 5E37-A nrPDB 71 2e-13 1FW4-A nrPDB 71 4e-13 2KN2-A nrPDB 70 5e-13 2LC5-A nrPDB 70 5e-13 3IFK-A nrPDB 69 1e-12 2KZ2-A nrPDB 69 2e-12 2N7L-C nrPDB 67 4e-12 2AMI-A nrPDB 67 5e-12 2RO9-A nrPDB 67 5e-12 5COC-A nrPDB 67 6e-12 5VLN-A nrPDB 67 6e-12 2M5E-A nrPDB 65 1e-11 2ROB-A nrPDB 64 3e-11 2LV7-A nrPDB 64 3e-11 2I08-A nrPDB 64 4e-11 4N5X-A nrPDB 64 6e-11 4ZCV-A nrPDB 63 7e-11 5H7D-E nrPDB 63 9e-11 2JNX-A nrPDB 63 1e-10 2RO8-A nrPDB 62 2e-10 4GJF-A nrPDB 60 4e-10 3AAJ-A nrPDB 60 5e-10 2B1U-A nrPDB 60 7e-10 5OTJ-D nrPDB 59 9e-10 4Q57-A nrPDB 59 1e-09 2BL0-B nrPDB 59 1e-09 1F55-A nrPDB 58 2e-09 2Q4U-A nrPDB 58 3e-09 1JFJ-A nrPDB 57 4e-09 2K7C-A nrPDB 57 5e-09 1JC2-A nrPDB 57 6e-09 1OZS-A nrPDB 57 7e-09 2LVK-A nrPDB 56 8e-09 1M39-A nrPDB 56 1e-08 5TBY-E nrPDB 55 2e-08 1TNP-A nrPDB 55 2e-08 1C7W-A nrPDB 54 3e-08 1W7I-B nrPDB 54 4e-08 1Y1X-A nrPDB 54 4e-08 2G9B-A nrPDB 53 5e-08 4D1E-A nrPDB 53 5e-08 4P5W-A nrPDB 53 6e-08 1TRF-A nrPDB 53 7e-08 1OQP-A nrPDB 53 9e-08 2N8Y-A nrPDB 52 1e-07 1YX7-A nrPDB 52 2e-07 5JOJ-A nrPDB 51 3e-07 1QXP-A nrPDB 51 3e-07 3KPX-A nrPDB 51 3e-07 5JOL-A nrPDB 51 3e-07 2OPO-A nrPDB 51 3e-07 1SR6-C nrPDB 51 4e-07 3JAX-C nrPDB 50 4e-07 4P5X-A nrPDB 50 4e-07 2VRG-A nrPDB 50 5e-07 1JF0-A nrPDB 50 5e-07 1ZMZ-A nrPDB 50 5e-07 2K2A-A nrPDB 50 6e-07 3LCP-C nrPDB 50 6e-07 3A4U-B nrPDB 50 6e-07 2KSZ-A nrPDB 50 6e-07 6MI5-X nrPDB 50 7e-07 1O1A-B nrPDB 50 7e-07 1H4B-A nrPDB 50 7e-07 6IIE-A nrPDB 50 8e-07 5Z1Q-A nrPDB 50 8e-07 2K2I-A nrPDB 50 8e-07 1S36-A nrPDB 50 8e-07 3AKA-A nrPDB 49 1e-06 3MSE-B nrPDB 49 1e-06 2M8U-A nrPDB 49 1e-06 4YGB-B nrPDB 49 1e-06 1SL8-A nrPDB 48 2e-06 5XND-A nrPDB 48 2e-06 1GGW-A nrPDB 48 2e-06 4NQG-A nrPDB 48 2e-06 5XOP-A nrPDB 48 3e-06 1NYA-A nrPDB 48 3e-06 5ZGM-A nrPDB 48 3e-06 1UHK-A nrPDB 48 3e-06 2JOJ-A nrPDB 48 3e-06 5VE9-A nrPDB 47 4e-06 5PAL-A nrPDB 47 6e-06 5H53-B nrPDB 47 7e-06 5H53-C nrPDB 46 9e-06 5E1J-A nrPDB 46 9e-06 3SIA-A nrPDB 46 1e-05 2NCO-A nrPDB 46 1e-05 1N2D-A nrPDB 46 1e-05 4OKH-A nrPDB 45 1e-05 5B7X-A nrPDB 45 1e-05 2M7M-A nrPDB 45 1e-05 1IJ5-A nrPDB 45 2e-05 3DTP-E nrPDB 45 2e-05 2KYF-A nrPDB 45 2e-05 1GJY-A nrPDB 45 2e-05 3I5H-B nrPDB 45 3e-05 2KQY-A nrPDB 44 4e-05 4L9M-A nrPDB 44 4e-05 3I5I-C nrPDB 44 4e-05 2MA2-A nrPDB 44 5e-05 6EAZ-A nrPDB 44 5e-05 1JUO-A nrPDB 43 6e-05 1QX2-A nrPDB 43 7e-05 2K7B-A nrPDB 43 8e-05 5MRA-A nrPDB 43 1e-04 1RTP-1 nrPDB 42 1e-04 4MSP-A nrPDB 42 1e-04 2LVV-A nrPDB 42 1e-04 4I5L-B nrPDB 42 2e-04 1RK9-A nrPDB 42 2e-04 4NSC-A nrPDB 42 2e-04 3JBH-C nrPDB 41 2e-04 3PAT-A nrPDB 41 3e-04 1F4Q-A nrPDB 41 3e-04 1TIZ-A nrPDB 41 4e-04 1A75-A nrPDB 41 4e-04 6FSA-D nrPDB 41 4e-04 3TZ1-A nrPDB 40 4e-04 3J04-B nrPDB 40 4e-04 4MEW-A nrPDB 40 4e-04 2SAS-A nrPDB 40 5e-04 6AGH-A nrPDB 40 5e-04 5ZH6-A nrPDB 40 5e-04 5I2L-A nrPDB 40 5e-04 3CS1-A nrPDB 40 6e-04 5CPV-A nrPDB 40 6e-04 1G33-A nrPDB 40 6e-04 4PAL-A nrPDB 40 6e-04 1S6J-A nrPDB 40 7e-04 3DF0-A nrPDB 40 7e-04 2W4G-C nrPDB 40 7e-04 5TBY-C nrPDB 40 7e-04 1KFX-S nrPDB 40 8e-04 4OCI-A nrPDB 40 9e-04 2FCE-A nrPDB 40 9e-04 2PMY-A nrPDB 39 0.001 3A8R-A nrPDB 39 0.001 2NLN-A nrPDB 39 0.001 6AGI-A nrPDB 38 0.002 2M1U-A nrPDB 38 0.002 1BU3-A nrPDB 38 0.002 5VT9-A nrPDB 38 0.002 1CB1-A nrPDB 38 0.003 2LUC-A nrPDB 38 0.003 1BOD-A nrPDB 37 0.004 1TTX-A nrPDB 37 0.004 3BOW-B nrPDB 37 0.006 1NSH-A nrPDB 37 0.007 2I18-A nrPDB 36 0.009 1QLS-A nrPDB 36 0.010 2MBX-A nrPDB 36 0.011 1Q80-A nrPDB 36 0.012 5MKE-A nrPDB 36 0.013 6D1W-A nrPDB 35 0.014 6DS2-B nrPDB 35 0.016 1ZFS-A nrPDB 35 0.018 2EC6-B nrPDB 35 0.020 2OS8-B nrPDB 35 0.021 1KQV-A nrPDB 35 0.028 6DU8-A nrPDB 34 0.033 2MJW-B nrPDB 34 0.037 4I5K-A nrPDB 34 0.040 4C0K-A nrPDB 34 0.049 2L50-A nrPDB 33 0.052 1B7T-Y nrPDB 33 0.057 1NP8-A nrPDB 33 0.066 2KHN-A nrPDB 33 0.073 2WCE-A nrPDB 33 0.079 3TS5-B nrPDB 33 0.083 2L0P-A nrPDB 33 0.087 2KGR-A nrPDB 33 0.093 1WY9-A nrPDB 32 0.12 1KFU-L nrPDB 32 0.12 5HYD-A nrPDB 32 0.13 1DFK-Y nrPDB 32 0.14 5CSF-A nrPDB 32 0.18 5W1A-B nrPDB 32 0.20 3H4S-E nrPDB 32 0.22 2JQ6-A nrPDB 31 0.26 1I84-U nrPDB 31 0.27 4HRG-A nrPDB 31 0.27 4FTG-A nrPDB 31 0.27 5X2E-A nrPDB 31 0.31 2KFH-A nrPDB 31 0.32 2JXC-A nrPDB 31 0.34 1NUB-A nrPDB 31 0.34 2Y5I-A nrPDB 31 0.37 1QJT-A nrPDB 31 0.42 1SNL-A nrPDB 30 0.47 4PCW-A nrPDB 30 0.47 2VTG-A nrPDB 30 0.48 2AUC-A nrPDB 30 0.56 4YBH-B nrPDB 30 0.57 2MHH-A nrPDB 30 0.61 5MVF-A nrPDB 30 0.63 3MNP-A nrPDB 30 0.69 5HLO-A nrPDB 30 0.73 1C07-A nrPDB 30 0.82 5KU1-A nrPDB 30 0.83 6HIV-CJ nrPDB 30 0.86 5LXV-B nrPDB 30 0.93 5W2O-A nrPDB 30 0.96 4A7Z-A nrPDB 29 0.97 1DJX-A nrPDB 29 1.0 4F8X-A nrPDB 29 1.2 4V1O-Q nrPDB 29 1.2 5OLW-A nrPDB 29 1.3 3TQO-A nrPDB 29 1.6 2KAY-A nrPDB 28 1.7 1SJJ-A nrPDB 28 1.7 5CUU-A nrPDB 28 1.7 3FSR-A nrPDB 28 1.7 3FPC-A nrPDB 28 1.7 2QPT-A nrPDB 28 1.7 2JMM-A nrPDB 28 1.7 1YKF-A nrPDB 28 1.7 2JTT-A nrPDB 28 1.8 6EMI-A nrPDB 28 2.0 2K60-A nrPDB 28 2.0 2KLD-A nrPDB 28 2.0 1FI6-A nrPDB 28 2.1 3NSO-A nrPDB 28 2.1 1SRA-A nrPDB 28 2.7 4I0B-A nrPDB 28 2.8 6QAA-A nrPDB 28 3.1 4QHP-A nrPDB 28 3.2 4AOM-A nrPDB 27 3.8 3KCC-A nrPDB 27 4.0 3GBX-A nrPDB 27 4.0 2CXJ-A nrPDB 27 4.1 2GS4-A nrPDB 27 4.2 2G2B-A nrPDB 27 4.7 5LJ6-A nrPDB 27 4.7 2JBS-A nrPDB 27 4.7 4CZY-B nrPDB 27 4.9 2G0Q-A nrPDB 27 5.0 3NA5-A nrPDB 27 5.2 2Y3N-B nrPDB 27 5.3 4YRV-B nrPDB 27 5.4 2KQ6-A nrPDB 27 5.4 2L5Y-A nrPDB 27 6.5 4F52-A nrPDB 27 6.5 1WLM-A nrPDB 27 6.9 5NRM-B nrPDB 27 7.3 5AHV-F nrPDB 27 7.3 3RTR-A nrPDB 27 7.3 3B97-A nrPDB 27 7.3 5NRK-B nrPDB 27 7.7 1F6V-A nrPDB 27 8.0 6IML-A nrPDB 26 8.2 4DUQ-A nrPDB 26 9.0 1YP3-A nrPDB 26 9.4 4EME-A nrPDB 26 9.8 2OZ6-A nrPDB 26 9.9 >2L2E-A nrPDB Length = 190 Score = 244 bits (623), Expect = 2e-65, Method: Composition-based stats. Identities = 189/189 (100%), Positives = 189/189 (100%) Query: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP Sbjct: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM Sbjct: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS Sbjct: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 Query: 182 ALSLYDGLV 190 ALSLYDGLV Sbjct: 182 ALSLYDGLV 190 >2LCP-A nrPDB Length = 190 Score = 231 bits (590), Expect = 1e-61, Method: Composition-based stats. Identities = 132/190 (69%), Positives = 161/190 (84%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MGKS SKL + +++L R T F +KE+QQWYKGF KDCPSG L+ + FQKIYKQFFPFGD Sbjct: 1 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 60 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 P+ FA +VFNVFD +K+G I+F EFI ALSVTSRG L++KL WAF+LYDLDN+G I+ +E Sbjct: 61 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 ML IVDAIY+MVG+ V+LPE+E+TPEKRV++IF MMDKN DG+LTL+EF EGSK DP+IV Sbjct: 121 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIV 180 Query: 181 SALSLYDGLV 190 ALSLYDGLV Sbjct: 181 QALSLYDGLV 190 >5T7C-A nrPDB Length = 193 Score = 228 bits (581), Expect = 1e-60, Method: Composition-based stats. Identities = 115/183 (62%), Positives = 135/183 (73%) Query: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 GK SKL + LQDL +T F ELQ+WYKGF KDCP+GHL EF+KIY FFP+GD Sbjct: 2 GKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDA 61 Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 S FAE+VF FD + +G IDF+EFI ALSVTSRG+L KL WAF +YDLD NG IS EM Sbjct: 62 SKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEM 121 Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 L IV AIYKMV S++K+PEDE TPEKR +KIF MD N DG+L+LEEF G+K DP+IV Sbjct: 122 LEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVR 181 Query: 182 ALS 184 L Sbjct: 182 LLQ 184 >1BJF-A nrPDB Length = 193 Score = 227 bits (580), Expect = 2e-60, Method: Composition-based stats. Identities = 116/184 (63%), Positives = 140/184 (76%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MGK SKL + +QDL+ ST F + E+Q+WYKGF +DCPSGHL+ EF+KIY FFP+GD Sbjct: 1 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD 60 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 S FAE+VF FDA+ +G IDF+EFI ALSVTSRG+L KL WAF +YDLD NG IS E Sbjct: 61 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 ML IV AIYKMV S++K+PEDE TPEKR KIF MD N+DG+L+LEEF G+K DP+IV Sbjct: 121 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIV 180 Query: 181 SALS 184 L Sbjct: 181 RLLQ 184 >2JU0-A nrPDB Length = 190 Score = 224 bits (571), Expect = 2e-59, Method: Composition-based stats. Identities = 119/190 (62%), Positives = 150/190 (78%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MG SKLS+D L L +ST FD++E+QQW+KGF +DCPSG L + +F KIYKQFFPFG Sbjct: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 P FA ++F VFD D NG+I F+EFI LS TSRG L +KL WAF+LYDL+++G I++DE Sbjct: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 ML IV ++YKM+GSMV L EDE TPE RV KIF +MDKN+DG +TL+EF EGSK DP+I+ Sbjct: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 Query: 181 SALSLYDGLV 190 AL+LYDGL+ Sbjct: 181 GALNLYDGLI 190 >5M6C-E nrPDB Length = 193 Score = 222 bits (567), Expect = 6e-59, Method: Composition-based stats. Identities = 116/184 (63%), Positives = 137/184 (74%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MGK SKL + LQDL +T F + ELQ+WYKGF KDCP+G LN EF+KIY FFP+GD Sbjct: 1 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGD 60 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 S FAE+VF FD + +G IDF+EFI ALSVTSRG L KL+WAF +YDLD NG IS +E Sbjct: 61 ASKFAEHVFRNFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 ML IV AIYKMV S++K+PEDE TPEKR KIF MD N DG+L+LEEF G+K DP+IV Sbjct: 121 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV 180 Query: 181 SALS 184 L Sbjct: 181 RLLQ 184 >2JUL-A nrPDB Length = 256 Score = 214 bits (545), Expect = 2e-56, Method: Composition-based stats. Identities = 76/187 (40%), Positives = 122/187 (65%) Query: 4 SQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSA 63 S + + L L T+F KKELQ Y+GF +CP+G +++ F+ IY QFFP GD + Sbjct: 70 STVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATT 129 Query: 64 FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 +A ++FN FDAD NG I F++F+ LS+ RG +++KL WAF LYD++ +G I+ +EML Sbjct: 130 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 Query: 124 IVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSAL 183 I+ +IY M+G ED P + V + F MD+N+DG +T++EF E ++D I++++ Sbjct: 190 IMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSM 249 Query: 184 SLYDGLV 190 L++ ++ Sbjct: 250 QLFENVI 256 >6EPA-A nrPDB Length = 187 Score = 206 bits (525), Expect = 4e-54, Method: Composition-based stats. Identities = 114/185 (61%), Positives = 141/185 (76%), Gaps = 1/185 (0%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MGK SKL QD + L T F +KE++QW+KGF KDCP+G L + F KIYKQFFP GD Sbjct: 1 MGKKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGD 60 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 PS FA VF VFD + +G I+F+EFI ALS+TSRG L++KL WAF+LYD+DN+G I+ +E Sbjct: 61 PSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 M IVDAIY+MVG + EDE+TP+KRV+KIF+ MDKN D +LTLEEF EGSK DP +V Sbjct: 121 MYNIVDAIYQMVGQQPQ-TEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMV 179 Query: 181 SALSL 185 ALSL Sbjct: 180 QALSL 184 >3DD4-A nrPDB Length = 229 Score = 201 bits (511), Expect = 2e-52, Method: Composition-based stats. Identities = 78/182 (42%), Positives = 118/182 (64%) Query: 9 SQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYV 68 + L+ L ++F KKELQ Y+GF +CPSG +N+ F++IY QFFP GD + +A ++ Sbjct: 48 RPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFL 107 Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 FN FD D NG + F++FI LS+ RG + +KL WAF LYD++ +G I+ +EML I+ AI Sbjct: 108 FNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAI 167 Query: 129 YKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDG 188 Y M+G ED P + V F MDKNKDG +T++EF E ++D I+ ++ L++ Sbjct: 168 YDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFEN 227 Query: 189 LV 190 ++ Sbjct: 228 VI 229 >1S6C-A nrPDB Length = 183 Score = 201 bits (511), Expect = 2e-52, Method: Composition-based stats. Identities = 80/182 (43%), Positives = 117/182 (64%) Query: 9 SQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYV 68 + L+ L T F K+ELQ Y+GF +CPSG +N+ F++IY QFFP GD S +A Y+ Sbjct: 2 RPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYL 61 Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 FN FD + G + F++F+ ALS+ RG +++KL W F LYD++ +G I+ +EM+ IV AI Sbjct: 62 FNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAI 121 Query: 129 YKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDG 188 Y M+G EDTP + V+ F MDKNKDG +TL+EF E + D I+ +L L+ Sbjct: 122 YDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQN 181 Query: 189 LV 190 ++ Sbjct: 182 VM 183 >1S1E-A nrPDB Length = 224 Score = 200 bits (509), Expect = 3e-52, Method: Composition-based stats. Identities = 80/182 (43%), Positives = 117/182 (64%) Query: 9 SQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYV 68 + L+ L T F K+ELQ Y+GF +CPSG +N+ F++IY QFFP GD S +A Y+ Sbjct: 35 RPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYL 94 Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 FN FD + G + F++F+ ALS+ RG +++KL W F LYD++ +G I+ +EM+ IV AI Sbjct: 95 FNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAI 154 Query: 129 YKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDG 188 Y M+G EDTP + V+ F MDKNKDG +TL+EF E + D I+ +L L+ Sbjct: 155 YDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQN 214 Query: 189 LV 190 ++ Sbjct: 215 VM 216 >2I94-A nrPDB Length = 202 Score = 187 bits (475), Expect = 2e-48, Method: Composition-based stats. Identities = 90/187 (48%), Positives = 127/187 (67%), Gaps = 3/187 (1%) Query: 1 MGKSQS-KLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFG 59 MG S+S LS++ L++L +T+F ++EL WY+ F K+CPSG + + EFQ IY +FFP Sbjct: 1 MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEA 60 Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 DP A+A++VF FDA+ +G +DFKE++ AL +TS G+ N KL WAF LYD+D NG IS + Sbjct: 61 DPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKN 120 Query: 120 EMLRIVDAIYKMVGS--MVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDP 177 E+L IV AI+KM+ LPEDE+TPEKR KI+ K D +LT +EF EG+ + Sbjct: 121 EVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIEGTLANK 180 Query: 178 TIVSALS 184 I+ + Sbjct: 181 EILRLIQ 187 >2D8N-A nrPDB Length = 207 Score = 178 bits (452), Expect = 1e-45, Method: Composition-based stats. Identities = 83/180 (46%), Positives = 124/180 (68%), Gaps = 2/180 (1%) Query: 7 KLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAE 66 LS++ L++L +T+F ++EL WY+ F KDCP+G + + +FQ IY +FFP DP A+A+ Sbjct: 15 ALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQ 74 Query: 67 YVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 +VF FD++ +G +DFKE++ AL +T+ G+ N KL WAF LYD+D NG IS +E+L IV Sbjct: 75 HVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVM 134 Query: 127 AIYKMVGS--MVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALS 184 AI+KM+ + LP+DE+TPEKR KI+ KN D +LT +EF EG+ + I+ + Sbjct: 135 AIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQ 194 >1JBA-A nrPDB Length = 204 Score = 158 bits (399), Expect = 1e-39, Method: Composition-based stats. Identities = 68/186 (36%), Positives = 109/186 (58%), Gaps = 6/186 (3%) Query: 5 QSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAF 64 + S ++ ++ D +LQ+WYK F ++CPSG L EF++ +K + + + Sbjct: 2 GQQFSWEEAEENGAVGAADAAQLQEWYKKFLEECPSGTLFMHEFKRFFK-VPDNEEATQY 60 Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 E +F FD + + IDF E++ AL++ RG L KL W F++YD D NG I E+L I Sbjct: 61 VEAMFRAFDTNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDI 120 Query: 125 VDAIYKMVGSMVKLPEDED-----TPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTI 179 V++IYK+ + E E TPE+ V++IF ++D+N DGQL+L EF EG++RD + Sbjct: 121 VESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWV 180 Query: 180 VSALSL 185 + L + Sbjct: 181 MKMLQM 186 >2R2I-A nrPDB Length = 198 Score = 157 bits (398), Expect = 2e-39, Method: Composition-based stats. Identities = 61/164 (37%), Positives = 94/164 (57%), Gaps = 5/164 (3%) Query: 21 RFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYI 80 E QWYK F +CPSG L EF++ + + + E +F FD +K+GYI Sbjct: 10 ELSATECHQWYKKFMTECPSGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDFNKDGYI 69 Query: 81 DFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPE 140 DF E++ ALS+ +G+++ KL W F+LYD+D NG I E+L I+ AI + Sbjct: 70 DFMEYVAALSLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAIRA-----INRCN 124 Query: 141 DEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALS 184 + T E+ N +F+ +D N DG+L+LEEF EG ++D ++ L+ Sbjct: 125 EAMTAEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILT 168 >2NA0-A nrPDB Length = 205 Score = 154 bits (388), Expect = 3e-38, Method: Composition-based stats. Identities = 62/164 (37%), Positives = 94/164 (57%), Gaps = 4/164 (2%) Query: 21 RFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYI 80 E QWYK F +CPSG L EF++ + S + E +F FD +K+GYI Sbjct: 12 ELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPWASQYVEQMFETFDFNKDGYI 71 Query: 81 DFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPE 140 DF E+ ALS+ +G++ KL W F+LYD+D NG I DE+L I+ AI ++ + Sbjct: 72 DFMEYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIR----AINPCSD 127 Query: 141 DEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALS 184 T E+ + +F+ +D N DG+L+LEEF EG ++D ++ L+ Sbjct: 128 STMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLT 171 >3U0K-A nrPDB Length = 442 Score = 153 bits (386), Expect = 5e-38, Method: Composition-based stats. Identities = 38/173 (21%), Positives = 73/173 (42%), Gaps = 15/173 (8%) Query: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 G K ++ + T E ++ + F KD G + E + + Sbjct: 281 GAVMQKKTKGWEPTRDQLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-T 338 Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDE 120 A + + N DAD +G IDF EF+ ++ + + +++ AF+++D D NG IS E Sbjct: 339 EAELQDMINEVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAE 398 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 + ++ + E ++ V+++ D + DGQ+ EEF + Sbjct: 399 LRHVMTNLG------------EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 439 Score = 77.4 bits (189), Expect = 4e-15, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 1/105 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D G ++ EF + + D F VFD D NGYI Sbjct: 338 TEAELQDMINEVDAD-GDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 396 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 397 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 441 Score = 63.5 bits (153), Expect = 5e-11, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 47/126 (37%), Gaps = 29/126 (23%) Query: 80 IDFKEFICALSVTSRG--ELNDKL--------IWAFQLYDLDNNGLISYDEMLRIVDAIY 129 ++F + ++G D+L AF L+D D +G I+ E+ ++ ++ Sbjct: 275 VNFPSNGAVMQKKTKGWEPTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLG 334 Query: 130 KMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR-------DPTIVSA 182 + + E + + N +D + DG + EF R + I A Sbjct: 335 Q------------NPTEAELQDMINEVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREA 382 Query: 183 LSLYDG 188 ++D Sbjct: 383 FRVFDK 388 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+++ ++ F KD +G+++ +E + + + + D D +G +++ Sbjct: 375 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNL-GEKLTDEEVDEMIREADIDGDGQVNY 432 Query: 83 KEFICALSVT 92 +EF+ ++ Sbjct: 433 EEFVQMMTAK 442 >4IL1-A nrPDB Length = 823 Score = 152 bits (384), Expect = 9e-38, Method: Composition-based stats. Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 15/157 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD N Sbjct: 4 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 61 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ + Sbjct: 62 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG------- 114 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ D + DGQ+ EEF + Sbjct: 115 -----EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 136 bits (342), Expect = 7e-33, Method: Composition-based stats. Identities = 56/178 (31%), Positives = 91/178 (51%), Gaps = 22/178 (12%) Query: 16 LVRSTRFDKKELQQWYKGFFKDC--PSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFD 73 L + FD E+++ K F K SG L+ EF P + + V ++FD Sbjct: 166 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-----LPELQQNPLVQRVIDIFD 220 Query: 74 ADKNGYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D NG +DFKEFI +S S +G+ KL +AF++YD+D +G IS E+ +++ MV Sbjct: 221 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK---MMV 277 Query: 133 GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 G+ +K ++ V+K DK+ DG+++ EEFC +V L ++ +V Sbjct: 278 GNNLKDT----QLQQIVDKTIINADKDGDGRISFEEFC-------AVVGGLDIHKKMV 324 Score = 95.1 bits (235), Expect = 2e-20, Method: Composition-based stats. Identities = 39/177 (22%), Positives = 73/177 (41%), Gaps = 13/177 (7%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D +G ++ EF + + D F VFD D NGYI Sbjct: 45 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 103 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDE 142 E ++ ++++ + D+D +G ++Y+E ++++ A G E Sbjct: 104 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEAS 163 Query: 143 DTPE----------KRVNKIFNMMDKNKDGQLTLEEFCEG--SKRDPTIVSALSLYD 187 E KR+ K F +D + G L++EEF +++P + + ++D Sbjct: 164 YPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFD 220 Score = 60.4 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 37/158 (23%), Positives = 57/158 (36%), Gaps = 12/158 (7%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQ------WYKGFFKDCPSGHLNKSEFQKIYKQ 54 +GK KL D L ELQQ F D +G ++ EF + Q Sbjct: 180 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTD-GNGEVDFKEFIEGVSQ 238 Query: 55 FFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV-----TSRGELNDKLIWAFQLYD 109 F GD + F ++D DK+GYI E L + +L + D Sbjct: 239 FSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINAD 298 Query: 110 LDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEK 147 D +G IS++E +V + +V + + Sbjct: 299 KDGDGRISFEEFCAVVGGLDIHKKMVVDVGGGGGGMSE 336 Score = 60.0 bits (144), Expect = 7e-10, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 38/96 (39%), Gaps = 19/96 (19%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 59 Query: 160 KDGQLTLEEFCEGSKR-------DPTIVSALSLYDG 188 +G + EF R + I A ++D Sbjct: 60 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDK 95 >4OY4-A nrPDB Length = 415 Score = 151 bits (381), Expect = 2e-37, Method: Composition-based stats. Identities = 36/157 (22%), Positives = 69/157 (43%), Gaps = 15/157 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD + Sbjct: 11 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGD 68 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ + Sbjct: 69 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG------- 121 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ D + DGQ+ EEF + Sbjct: 122 -----EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 78.1 bits (191), Expect = 2e-15, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 46/108 (42%), Gaps = 1/108 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D G ++ EF + + D F VFD D NGYI Sbjct: 52 TEAELQDMINEVDAD-GDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 110 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 E ++ ++++ + D+D +G ++Y+E ++++ A + Sbjct: 111 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKLE 158 Score = 62.7 bits (151), Expect = 9e-11, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 38/96 (39%), Gaps = 19/96 (19%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 66 Query: 160 KDGQLTLEEFCEGSKR-------DPTIVSALSLYDG 188 DG + EF R + I A ++D Sbjct: 67 GDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDK 102 >3EK4-A nrPDB Length = 451 Score = 149 bits (376), Expect = 7e-37, Method: Composition-based stats. Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 15/157 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD N Sbjct: 306 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 363 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ + Sbjct: 364 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG------- 416 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ D + DGQ+ EEF + Sbjct: 417 -----EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 448 Score = 76.6 bits (187), Expect = 6e-15, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 1/105 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D +G ++ EF + + D F VFD D NGYI Sbjct: 347 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 405 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 406 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 450 Score = 66.2 bits (160), Expect = 8e-12, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 61/174 (35%), Gaps = 31/174 (17%) Query: 31 YKGFFKDCPSGHLNKSE-FQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL 89 + F P G++ + F K + + + + N + IDFKE L Sbjct: 239 HDFFKSAMPEGYIQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKG---IDFKEDGNIL 295 Query: 90 SVTSRGELNDKL--------IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPED 141 D+L AF L+D D +G I+ E+ ++ ++ + Sbjct: 296 GHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ----------- 344 Query: 142 EDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR-------DPTIVSALSLYDG 188 + E + + N +D + +G + EF R + I A ++D Sbjct: 345 -NPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDK 397 Score = 57.3 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+++ ++ F KD +G+++ +E + + + + D D +G +++ Sbjct: 384 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNL-GEKLTDEEVDEMIREADIDGDGQVNY 441 Query: 83 KEFICALSVT 92 +EF+ ++ Sbjct: 442 EEFVQMMTAK 451 >5UKG-A nrPDB Length = 419 Score = 145 bits (365), Expect = 1e-35, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 66/157 (42%), Gaps = 15/157 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD + Sbjct: 274 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGD 331 Query: 78 GYIDFKEFICALSVTSRGE-LNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G DF EF+ ++ +++ AF+++D D NG I E+ ++ + Sbjct: 332 GTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLG------- 384 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ + D + DGQ+ EEF + Sbjct: 385 -----EKLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 416 Score = 61.6 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 37/96 (38%), Gaps = 19/96 (19%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 282 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 329 Query: 160 KDGQLTLEEFCEGSKR-------DPTIVSALSLYDG 188 DG EF R + I A ++D Sbjct: 330 GDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDK 365 Score = 57.7 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+++ ++ F KD +G++ +E + + + + V D D +G +++ Sbjct: 352 TEEEIREAFRVFDKD-GNGYIGAAELRHVMTDL-GEKLTDEEVDEMIRVADIDGDGQVNY 409 Query: 83 KEFICALSVT 92 +EF+ ++ Sbjct: 410 EEFVQMMTAK 419 >2GGZ-A nrPDB Length = 211 Score = 143 bits (361), Expect = 4e-35, Method: Composition-based stats. Identities = 52/158 (32%), Positives = 86/158 (54%), Gaps = 6/158 (3%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 +E WY+ F + PSG EF+ + + + V+N FD +K+G++DF Sbjct: 18 TQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 77 Query: 84 EFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDED 143 EFI A+++ + ++ KL W F+LYD D NG I +E+L + A+ + G Sbjct: 78 EFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL------ 131 Query: 144 TPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 +PE+ +N +F+ +D N DG+LTLEEF G +D ++ Sbjct: 132 SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLE 169 >4I2Y-A nrPDB Length = 421 Score = 142 bits (357), Expect = 1e-34, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 15/157 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD + Sbjct: 276 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGD 333 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G DF EF+ ++ + +++ AF+++D D NG I E+ ++ + Sbjct: 334 GTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLG------- 386 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ + D + DGQ+ EEF + Sbjct: 387 -----EKLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 418 Score = 76.6 bits (187), Expect = 7e-15, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 1/105 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D G + EF + + D F VFD D NGYI Sbjct: 317 TEAELQDMINEVDAD-GDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGA 375 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 E ++ ++++ ++ D+D +G ++Y+E ++++ A Sbjct: 376 AELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTA 420 Score = 59.6 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 37/96 (38%), Gaps = 19/96 (19%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 284 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 331 Query: 160 KDGQLTLEEFCEGSKR-------DPTIVSALSLYDG 188 DG EF R + I A ++D Sbjct: 332 GDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDK 367 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+++ ++ F KD +G++ +E + + + + V D D +G +++ Sbjct: 354 SEEEIREAFRVFDKD-GNGYIGAAELRHVMTDL-GEKLTDEEVDEMIRVADIDGDGQVNY 411 Query: 83 KEFICALSVT 92 +EF+ ++ Sbjct: 412 EEFVQMMTAK 421 >1V1G-A nrPDB Length = 222 Score = 141 bits (356), Expect = 2e-34, Method: Composition-based stats. Identities = 58/199 (29%), Positives = 100/199 (50%), Gaps = 20/199 (10%) Query: 1 MGKSQSKLSQ---------DQLQDLVRSTRFDKKELQQWYKGFFKDCPS----GHLNKSE 47 MG S SK + + + L T F +E++ Y+ F K S G ++K E Sbjct: 1 MGCSVSKKKKKNAMRPPGYEDPELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEE 60 Query: 48 FQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV-TSRGELNDKLIWAFQ 106 FQ F + FA+ +F+VFD +NG I+F EF+ +L V +++K+ +AF+ Sbjct: 61 FQ--LALFRNRNRRNLFADRIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFK 118 Query: 107 LYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTL 166 LYDL G I +E+ +V A+ +L ED E V+K F D+ DG++ + Sbjct: 119 LYDLRQTGFIEREELKEMVVALLHE----SELVLSEDMIEVMVDKAFVQADRKNDGKIDI 174 Query: 167 EEFCEGSKRDPTIVSALSL 185 +E+ + +P+++ ++L Sbjct: 175 DEWKDFVSLNPSLIKNMTL 193 >2ZFD-A nrPDB Length = 226 Score = 138 bits (349), Expect = 9e-34, Method: Composition-based stats. Identities = 58/177 (32%), Positives = 87/177 (49%), Gaps = 11/177 (6%) Query: 14 QDLVRSTRFDKKELQQWYKGFFKDC----PSGHLNKSEFQKIYKQFFPFGDPSAFAEYVF 69 + L R T F E++ Y+ F K G +NK EFQ F S FA+ VF Sbjct: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 Query: 70 NVFDADKNGYIDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 ++FD NG + F+EF ALSV ++DK+ ++FQLYDL G I E+ ++V A Sbjct: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 Query: 129 YKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 G +K ED ++K F D DG++ EE+ R P+++ ++L Sbjct: 152 LAESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 >3HZT-A nrPDB Length = 467 Score = 138 bits (348), Expect = 1e-33, Method: Composition-based stats. Identities = 41/185 (22%), Positives = 82/185 (44%), Gaps = 27/185 (14%) Query: 3 KSQSKLSQDQLQDL--VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFG- 59 +S KL+Q + + +T + KEL Q ++ + G L++ E + Y++ + Sbjct: 290 QSSQKLAQAAMLFMGSKLTTLEETKELTQIFRQ-LDNNGDGQLDRKELIEGYRKLMQWKG 348 Query: 60 ---------DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDL 110 A +++ D D+NGYI++ EF+ ++L+ AFQ +D Sbjct: 349 DTVSDLDSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDS 408 Query: 111 DNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 D +G I+ +E+ R+ + ++ +++ DKN DG++ EEF Sbjct: 409 DGSGKITNEELGRLFGVT--------------EVDDETWHQVLQECDKNNDGEVDFEEFV 454 Query: 171 EGSKR 175 E ++ Sbjct: 455 EMMQK 459 Score = 49.6 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 36/97 (37%), Gaps = 1/97 (1%) Query: 85 FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDT 144 + S + E +L F+ D + +G + E++ + + G D Sbjct: 300 MLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKG-DTVSDLDSSQ 358 Query: 145 PEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 E V+ I +D +++G + EF ++S Sbjct: 359 IEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLLS 395 >1UHN-A nrPDB Length = 189 Score = 134 bits (338), Expect = 2e-32, Method: Composition-based stats. Identities = 58/177 (32%), Positives = 87/177 (49%), Gaps = 11/177 (6%) Query: 14 QDLVRSTRFDKKELQQWYKGFFKDC----PSGHLNKSEFQKIYKQFFPFGDPSAFAEYVF 69 + L R T F E++ Y+ F K G +NK EFQ F S FA+ VF Sbjct: 3 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 60 Query: 70 NVFDADKNGYIDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 ++FD NG + F+EF ALSV ++DK+ ++FQLYDL G I E+ ++V A Sbjct: 61 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 120 Query: 129 YKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 G +K ED ++K F D DG++ EE+ R P+++ ++L Sbjct: 121 LAESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 173 >3WFN-B nrPDB Length = 182 Score = 134 bits (338), Expect = 2e-32, Method: Composition-based stats. Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 15/157 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD N Sbjct: 10 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 67 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ + Sbjct: 68 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG------- 120 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ D + DGQ+ EEF + Sbjct: 121 -----EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 152 Score = 70.8 bits (172), Expect = 3e-13, Method: Composition-based stats. Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D +G ++ EF + + D F VFD D NGYI Sbjct: 51 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 109 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 E ++ ++++ + D+D +G ++Y+E ++++ A G V Sbjct: 110 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGEEV 163 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 38/96 (39%), Gaps = 19/96 (19%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 18 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 65 Query: 160 KDGQLTLEEFCEGSKR-------DPTIVSALSLYDG 188 +G + EF R + I A ++D Sbjct: 66 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDK 101 >2N6A-A nrPDB Length = 173 Score = 133 bits (336), Expect = 3e-32, Method: Composition-based stats. Identities = 37/155 (23%), Positives = 68/155 (43%), Gaps = 15/155 (9%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 T E ++ + F KD G + E + + A + + N DAD NG Sbjct: 7 TEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGNGT 64 Query: 80 IDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKL 138 IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ + Sbjct: 65 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG--------- 115 Query: 139 PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ D + DGQ+ EEF + Sbjct: 116 ---EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 147 Score = 69.7 bits (169), Expect = 7e-13, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 47/112 (41%), Gaps = 1/112 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D +G ++ EF + + D F VFD D NGYI Sbjct: 46 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 104 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGS 134 E ++ ++++ + D+D +G ++Y+E ++++ GS Sbjct: 105 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTGASTAAGS 156 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 38/96 (39%), Gaps = 19/96 (19%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 13 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 60 Query: 160 KDGQLTLEEFCEGSKR-------DPTIVSALSLYDG 188 +G + EF R + I A ++D Sbjct: 61 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDK 96 >5JN2-A nrPDB Length = 525 Score = 130 bits (328), Expect = 3e-31, Method: Composition-based stats. Identities = 43/185 (23%), Positives = 78/185 (42%), Gaps = 27/185 (14%) Query: 3 KSQSKLSQDQLQDL--VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 + KL+Q L + +++ + KEL + K+ G L+++E + YK+ Sbjct: 352 QGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKN-GDGQLDRAELIEGYKELMRMKG 410 Query: 61 PSA----------FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDL 110 A + V + D DKNGYI++ EF+ ++L AF+++D Sbjct: 411 QDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDS 470 Query: 111 DNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 DN+G IS E+ I D + + + +DKN DG++ +EF Sbjct: 471 DNSGKISSTELATIFGV--------------SDVDSETWKSVLSEVDKNNDGEVDFDEFQ 516 Query: 171 EGSKR 175 + + Sbjct: 517 QMLLK 521 Score = 57.0 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 24/159 (15%), Positives = 58/159 (36%), Gaps = 6/159 (3%) Query: 28 QQWYKGFFKDCPSGHLNK-----SEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + + PS ++ E+ + Y + D + + N+ + Sbjct: 300 KDLIRKMLTYVPSMRISARDALDHEWIQTYTKEQISVDVPSLDNAILNIRQFQGTQKLAQ 359 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDE 142 + S + + +L F D + +G + E++ + +M G + D Sbjct: 360 AALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASM-LDA 418 Query: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 E V+++ + +D +K+G + EF + T++S Sbjct: 419 SAVEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLS 457 >6O20-F nrPDB Length = 169 Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats. Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 15/157 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD N Sbjct: 24 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 81 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ + Sbjct: 82 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG------- 134 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ D + DGQ+ EEF + Sbjct: 135 -----EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 166 Score = 68.1 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 1/105 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D +G ++ EF + + D F VFD D NGYI Sbjct: 65 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 123 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 124 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 168 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 38/96 (39%), Gaps = 19/96 (19%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 32 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 79 Query: 160 KDGQLTLEEFCEGSKR-------DPTIVSALSLYDG 188 +G + EF R + I A ++D Sbjct: 80 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDK 115 Score = 50.4 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+++ ++ F KD +G+++ +E + + + + D D +G +++ Sbjct: 102 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNL-GEKLTDEEVDEMIREADIDGDGQVNY 159 Query: 83 KEFICALSVT 92 +EF+ ++ Sbjct: 160 EEFVQMMTAK 169 >2F2P-A nrPDB Length = 179 Score = 130 bits (326), Expect = 5e-31, Method: Composition-based stats. Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 15/157 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD N Sbjct: 4 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 61 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ + Sbjct: 62 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG------- 114 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ D + DGQ+ EEF + Sbjct: 115 -----EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 67.7 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 1/105 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D +G ++ EF + + D F VFD D NGYI Sbjct: 45 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 103 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 E ++ ++++ + D+D +G ++Y+E ++++ A Sbjct: 104 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148 Score = 50.4 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 59 Query: 160 KDGQLTLEEFCEGSKR 175 +G + EF R Sbjct: 60 GNGTIDFPEFLTMMAR 75 >2LM5-A nrPDB Length = 214 Score = 129 bits (325), Expect = 7e-31, Method: Composition-based stats. Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 14/194 (7%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCP-------SGHLNKSEFQKIYK 53 MG S S+LS++ L + T K+E+ ++ F + P S + F++I Sbjct: 24 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 83 Query: 54 QFFPFGDPSAFAEYVFNVFDAD-KNGYIDFKEFICALSVTSRGELND-KLIWAFQLYDLD 111 P + F E + VF + F++F+ LSV S D K +AF+++D D Sbjct: 84 --LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFD 141 Query: 112 NNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 ++G ++ +++ R+V+ + G +L E ++ ++ I D ++DG + L EF Sbjct: 142 DDGTLNREDLSRLVNCLTGE-GEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQH 198 Query: 172 GSKRDPTIVSALSL 185 R P S+ + Sbjct: 199 VISRSPDFASSFKI 212 >3LIJ-A nrPDB Length = 494 Score = 129 bits (324), Expect = 7e-31, Method: Composition-based stats. Identities = 45/182 (24%), Positives = 77/182 (42%), Gaps = 24/182 (13%) Query: 3 KSQSKLSQDQLQDLVR--STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF----- 55 ++ KL+Q L + +++ + KEL ++ K+ G L++ E Y + Sbjct: 322 QNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKN-GDGQLDRQELIDGYSKLSGEEV 380 Query: 56 --FPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNN 113 F + + + D D+NGYID+ EF+ DKL AFQ +D D N Sbjct: 381 AVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGN 440 Query: 114 GLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 G IS DE+ + + K ++ + +D N DG + EEFC+ Sbjct: 441 GKISVDELASVFGLDHLE--------------SKTWKEMISGIDSNNDGDVDFEEFCKMI 486 Query: 174 KR 175 ++ Sbjct: 487 QK 488 Score = 50.4 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 40/100 (40%), Gaps = 4/100 (4%) Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTP 145 + S + E +L F+ D + +G + E++ + ++ LP+ E Sbjct: 333 LYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIES-- 390 Query: 146 EKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 V+ I D +++G + EF + +++S L Sbjct: 391 --EVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKL 428 >4E53-A nrPDB Length = 185 Score = 127 bits (320), Expect = 2e-30, Method: Composition-based stats. Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 15/157 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD N Sbjct: 11 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 68 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ + Sbjct: 69 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG------- 121 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ D + DGQ+ EEF + Sbjct: 122 -----EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 49.6 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 66 Query: 160 KDGQLTLEEFCEGSKR 175 +G + EF R Sbjct: 67 GNGTIDFPEFLTMMAR 82 >5YPX-A nrPDB Length = 223 Score = 126 bits (317), Expect = 5e-30, Method: Composition-based stats. Identities = 49/188 (26%), Positives = 91/188 (48%), Gaps = 13/188 (6%) Query: 2 GKSQSKLSQDQLQDLVRST---RFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPF 58 G SK +Q ++L +++ F K E++ + ++++ F+ I Q F Sbjct: 18 GSHMSKKNQKLAEELYKTSCQKHFTKTEVESLIICYKNLLEGLKMDRNLFRDILHQKFNM 77 Query: 59 GDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISY 118 + + VF FD D + YI E++ LSV RG L++K+ + F ++DL+ +G IS Sbjct: 78 TE-DLLMDRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLDEKMEYTFTVFDLNGDGYISR 136 Query: 119 DEMLRIVDAIYKMVGSMVKLPEDEDTPE---KRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 +EM +++ +VK P +ED E V MD + D +L+ ++F + Sbjct: 137 EEMFQMLKT------CLVKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKKDFKDAVLI 190 Query: 176 DPTIVSAL 183 +P ++ A Sbjct: 191 EPLLLEAF 198 >6HCS-A nrPDB Length = 167 Score = 125 bits (314), Expect = 1e-29, Method: Composition-based stats. Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 15/172 (8%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD N Sbjct: 4 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 61 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF EF+ ++ + + +++ AF+++D D NG IS E+ + + Sbjct: 62 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLG------- 114 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDG 188 E ++ V+++ D + DGQ+ EEF + L+ G Sbjct: 115 -----EKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKLEGTGLEVLFQG 161 >3KHE-A nrPDB Length = 191 Score = 125 bits (313), Expect = 2e-29, Method: Composition-based stats. Identities = 41/185 (22%), Positives = 82/185 (44%), Gaps = 27/185 (14%) Query: 3 KSQSKLSQDQLQDL--VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFG- 59 +S KL+Q + + +T + KEL Q ++ + G L++ E + Y++ + Sbjct: 16 QSSQKLAQAAMLFMGSKLTTLEETKELTQIFRQ-LDNNGDGQLDRKELIEGYRKLMQWKG 74 Query: 60 ---------DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDL 110 A +++ D D+NGYI++ EF+ ++L+ AFQ +D Sbjct: 75 DTVSDLDSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDS 134 Query: 111 DNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 D +G I+ +E+ R+ + ++ +++ DKN DG++ EEF Sbjct: 135 DGSGKITNEELGRLFGVT--------------EVDDETWHQVLQECDKNNDGEVDFEEFV 180 Query: 171 EGSKR 175 E ++ Sbjct: 181 EMMQK 185 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 37/97 (38%), Gaps = 1/97 (1%) Query: 85 FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDT 144 + S + E +L F+ D + +G + E++ + + G V + Sbjct: 26 MLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQI 85 Query: 145 PEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 E V+ I +D +++G + EF ++S Sbjct: 86 -EAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLLS 121 >4YZB-A nrPDB Length = 491 Score = 122 bits (306), Expect = 9e-29, Method: Composition-based stats. Identities = 39/185 (21%), Positives = 71/185 (38%), Gaps = 27/185 (14%) Query: 3 KSQSKLSQDQLQDL--VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 + KL+ L + +T + EL + ++ K+ G L+K E + Y + Sbjct: 315 QGTQKLAAAALLYMGSKLTTNEETVELNKIFQRMDKN-GDGQLDKQELMEGYVELMKLKG 373 Query: 61 P----------SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDL 110 E V + D DKNG+I++ EF+ +L AF ++D Sbjct: 374 EDVSALDQSAIEFEVEQVLDAVDFDKNGFIEYSEFVTVAMDRKTLLSRQRLERAFGMFDA 433 Query: 111 DNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 D +G IS E+ I + + ++ +D+N DG++ EEF Sbjct: 434 DGSGKISSSELATIFGV--------------SEVDSETWRRVLAEVDRNNDGEVDFEEFR 479 Query: 171 EGSKR 175 + + Sbjct: 480 QMLLK 484 >4RGJ-A nrPDB Length = 520 Score = 122 bits (305), Expect = 1e-28, Method: Composition-based stats. Identities = 42/185 (22%), Positives = 78/185 (42%), Gaps = 27/185 (14%) Query: 3 KSQSKLSQDQLQDL--VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 +S KL+Q L + +T + KEL + +K K+ G L+++E YK+ Sbjct: 347 QSTQKLAQAALLYMGSKLTTIDETKELTKIFKKMDKN-GDGQLDRNELIIGYKELLKLKG 405 Query: 61 PSA----------FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDL 110 + + N D D+NGYI++ EF+ ++L AF+L+D Sbjct: 406 EDTSDLDNAAIEYEVDQILNSIDLDQNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDK 465 Query: 111 DNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 D +G IS +E+ ++ D + + +D+N DG++ +EF Sbjct: 466 DGSGKISANELAQLFGL--------------SDVSSECWKTVLKEVDQNNDGEIDFKEFR 511 Query: 171 EGSKR 175 + + Sbjct: 512 DMLVK 516 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 39/96 (40%), Gaps = 7/96 (7%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 +L F+ D + +G + +E++ + K+ G D E V++I N +D Sbjct: 371 KELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTS-DLDNAAIEYEVDQILNSIDL 429 Query: 159 NKDGQLTLEEF------CEGSKRDPTIVSALSLYDG 188 +++G + EF + + A L+D Sbjct: 430 DQNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDK 465 >5I0I-E nrPDB Length = 145 Score = 122 bits (305), Expect = 1e-28, Method: Composition-based stats. Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 15/157 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + KD G + E + + A + + N DAD N Sbjct: 2 QLTEEQIAEFKEAFSLADKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 59 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF EF+ ++ + + +++ AF+++D D NG IS E+ ++ + Sbjct: 60 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG------- 112 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V+++ D + DGQ+ EEF + Sbjct: 113 -----EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 144 Score = 65.0 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 45/104 (43%), Gaps = 1/104 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D +G ++ EF + + D F VFD D NGYI Sbjct: 43 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 101 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 E ++ ++++ + D+D +G ++Y+E ++++ Sbjct: 102 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 145 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 31/76 (40%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 57 Query: 160 KDGQLTLEEFCEGSKR 175 +G + EF R Sbjct: 58 GNGTIDFPEFLTMMAR 73 >4ORC-B nrPDB Length = 170 Score = 121 bits (303), Expect = 2e-28, Method: Composition-based stats. Identities = 56/178 (31%), Positives = 92/178 (51%), Gaps = 22/178 (12%) Query: 16 LVRSTRFDKKELQQWYKGFFKDC--PSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFD 73 L + FD E+++ K F K SG L+ EF + P + + V ++FD Sbjct: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 Query: 74 ADKNGYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D NG +DFKEFI +S S +G+ KL +AF++YD+D +G IS E+ +++ MV Sbjct: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK---MMV 120 Query: 133 GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 G+ +K ++ V+K DK+ DG+++ EEFC +V L ++ +V Sbjct: 121 GNNLKDT----QLQQIVDKTIINADKDGDGRISFEEFC-------AVVGGLDIHKKMV 167 >1CLM-A nrPDB Length = 148 Score = 120 bits (301), Expect = 4e-28, Method: Composition-based stats. Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 15/158 (9%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 T E ++ + F KD G + E + + A + + N DAD Sbjct: 2 QELTEEQIAEFKEAFALFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADG 59 Query: 77 NGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 NG IDF EF+ ++ + + ++LI AF+++D D NGLIS E+ ++ + Sbjct: 60 NGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLG------ 113 Query: 136 VKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E + V+++ D + DG + EEF Sbjct: 114 ------EKLTDDEVDEMIREADIDGDGHINYEEFVRMM 145 Score = 62.0 bits (149), Expect = 1e-10, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 45/105 (42%), Gaps = 1/105 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ D +G ++ EF + + D F VFD D NG I Sbjct: 44 TEAELQDMINEVDAD-GNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISA 102 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 E ++ +D++ + D+D +G I+Y+E +R++ + Sbjct: 103 AELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMMVS 147 Score = 49.6 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 39/95 (41%), Gaps = 19/95 (20%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 11 EFKEAFALFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 58 Query: 160 KDGQLTLEEFCEGSKR-------DPTIVSALSLYD 187 +G + EF R + ++ A ++D Sbjct: 59 GNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFD 93 >1DGU-A nrPDB Length = 183 Score = 120 bits (300), Expect = 5e-28, Method: Composition-based stats. Identities = 43/186 (23%), Positives = 84/186 (45%), Gaps = 14/186 (7%) Query: 9 SQDQLQDLVRSTRFDKKELQQWYKGFFKDCP-------SGHLNKSEFQKIYKQFFPFGDP 61 S++ L + T K+E+ ++ F + P S + F++I P Sbjct: 1 SKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS--LPELKA 58 Query: 62 SAFAEYVFNVFDAD-KNGYIDFKEFICALSVTSRGELND-KLIWAFQLYDLDNNGLISYD 119 + F E + VF + F++F+ LSV S D K +AF+++D D++G ++ + Sbjct: 59 NPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRE 118 Query: 120 EMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTI 179 ++ R+V+ + G +L E ++ ++ I D ++DG + L EF R P Sbjct: 119 DLSRLVNCLTGE-GEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQHVISRSPDF 175 Query: 180 VSALSL 185 S+ + Sbjct: 176 ASSFKI 181 >3L19-A nrPDB Length = 214 Score = 119 bits (299), Expect = 6e-28, Method: Composition-based stats. Identities = 45/182 (24%), Positives = 77/182 (42%), Gaps = 24/182 (13%) Query: 3 KSQSKLSQDQLQDLVR--STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF----- 55 ++ KL+Q L + +++ + KEL ++ K+ G L++ E Y + Sbjct: 39 QNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKN-GDGQLDRQELIDGYSKLSGEEV 97 Query: 56 --FPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNN 113 F + + + D D+NGYID+ EF+ DKL AFQ +D D N Sbjct: 98 AVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGN 157 Query: 114 GLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 G IS DE+ + + K ++ + +D N DG + EEFC+ Sbjct: 158 GKISVDELASVFGLDHLE--------------SKTWKEMISGIDSNNDGDVDFEEFCKMI 203 Query: 174 KR 175 ++ Sbjct: 204 QK 205 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 40/100 (40%), Gaps = 4/100 (4%) Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTP 145 + S + E +L F+ D + +G + E++ + ++ LP+ E Sbjct: 50 LYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIES-- 107 Query: 146 EKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 V+ I D +++G + EF + +++S L Sbjct: 108 --EVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKL 145 >3Q5I-A nrPDB Length = 504 Score = 118 bits (297), Expect = 9e-28, Method: Composition-based stats. Identities = 43/180 (23%), Positives = 71/180 (39%), Gaps = 24/180 (13%) Query: 5 QSKLSQDQLQDL--VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP- 61 KL+Q + + +T ++KEL +K K+ G L+K E + Y F + Sbjct: 333 SQKLAQAAILFIGSKLTTLEERKELTDIFKKLDKN-GDGQLDKKELIEGYNVLRNFKNEL 391 Query: 62 ------SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGL 115 + + D DKNGYI++ EFI ++L AF L+D D +G Sbjct: 392 GELKNVEEEVDNILKEVDFDKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTDKSGK 451 Query: 116 ISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 I+ +E+ + EK N + D+NKD + +EF + Sbjct: 452 ITKEELANLFGLT--------------SISEKTWNDVLGEADQNKDNMIDFDEFVSMMHK 497 >5A2H-A nrPDB Length = 149 Score = 117 bits (294), Expect = 2e-27, Method: Composition-based stats. Identities = 38/159 (23%), Positives = 69/159 (43%), Gaps = 15/159 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD N Sbjct: 4 QLTDDQISEFKEAFSLFDKD-GDGCITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 61 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF EF+ ++ + + ++L AF+++D D NG IS E+ ++ + Sbjct: 62 GTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLG------- 114 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E ++ V+++ D + DGQ+ EEF + Sbjct: 115 -----EKLTDEEVDEMIREADVDGDGQINYEEFVKVMMA 148 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 35/87 (40%), Gaps = 12/87 (13%) Query: 89 LSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKR 148 ++ + + AF L+D D +G I+ E+ ++ ++ + + E Sbjct: 1 MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQ------------NPTEAE 48 Query: 149 VNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + + N +D + +G + EF R Sbjct: 49 LQDMINEVDADGNGTIDFPEFLNLMAR 75 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++EL++ ++ F KD +G ++ +E + + + + D D +G I++ Sbjct: 82 SEEELKEAFRVFDKD-QNGFISAAELRHVMTNL-GEKLTDEEVDEMIREADVDGDGQINY 139 Query: 83 KEFICALSVT 92 +EF+ + Sbjct: 140 EEFVKVMMAK 149 >5B8I-B nrPDB Length = 171 Score = 117 bits (292), Expect = 4e-27, Method: Composition-based stats. Identities = 52/181 (28%), Positives = 93/181 (51%), Gaps = 16/181 (8%) Query: 8 LSQDQLQDLVRSTRFDKKELQQWYKGFFK--DCPSGHLNKSEFQKIYKQFFPFGDPSAFA 65 +S L D+V + FD +E+ + +K F K SG + + EF + P + + Sbjct: 1 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSL-----PQVSSNPLS 55 Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 + +FD D G +DF+EF+ LS S +G +KL +AF++YD+D +G IS E+ + Sbjct: 56 TRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIV 115 Query: 125 VDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALS 184 + MVGS +K + ++ V+K D + DG+++ EEF + + +++ Sbjct: 116 LK---MMVGSNLK----DMQLQQIVDKTIMEADLDGDGRISFEEFTRMV-ENTDVSMSMT 167 Query: 185 L 185 L Sbjct: 168 L 168 >1GGZ-A nrPDB Length = 148 Score = 115 bits (287), Expect = 1e-26, Method: Composition-based stats. Identities = 32/156 (20%), Positives = 66/156 (42%), Gaps = 15/156 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + + + + + D D N Sbjct: 3 QLTEEQVTEFKEAFSLFDKD-GDGCITTRELGTVMRSLGQNPTEAELRD-MMSEIDRDGN 60 Query: 78 GYIDFKEFICALSVTSRGEL-NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G +DF EF+ ++ + +++ AF+++D D NG +S E+ ++ + Sbjct: 61 GTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLG------- 113 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEG 172 E ++ V+++ D + DGQ+ EEF Sbjct: 114 -----EKLSDEEVDEMIRAADTDGDGQVNYEEFVRV 144 Score = 62.7 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 21/105 (20%), Positives = 46/105 (43%), Gaps = 1/105 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + EL+ +D +G ++ EF + + D F VFD D NG++ Sbjct: 44 TEAELRDMMSEIDRD-GNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSA 102 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 E ++ ++++ + D D +G ++Y+E +R++ + Sbjct: 103 AELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLVS 147 Score = 50.0 bits (118), Expect = 7e-07, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 33/76 (43%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + + +D++ Sbjct: 11 EFKEAFSLFDKDGDGCITTRELGTVMRSLGQ------------NPTEAELRDMMSEIDRD 58 Query: 160 KDGQLTLEEFCEGSKR 175 +G + EF R Sbjct: 59 GNGTVDFPEFLGMMAR 74 >2E6W-A nrPDB Length = 100 Score = 112 bits (280), Expect = 9e-26, Method: Composition-based stats. Identities = 38/97 (39%), Positives = 64/97 (65%) Query: 94 RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIF 153 G +++KL WAF LYD++ +G I+ +EML I+ +IY M+G ED P + V + F Sbjct: 4 MGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFF 63 Query: 154 NMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 MD+N+DG +T+EEF E ++D I+S++ L++ ++ Sbjct: 64 EKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI 100 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 34/80 (42%), Gaps = 12/80 (15%) Query: 68 VFNVFDADKNGYIDFKEFICALS------------VTSRGELNDKLIWAFQLYDLDNNGL 115 FN++D +K+GYI +E + + + + + F+ D + +G+ Sbjct: 14 AFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGV 73 Query: 116 ISYDEMLRIVDAIYKMVGSM 135 ++ +E L ++ SM Sbjct: 74 VTIEEFLEACQKDENIMSSM 93 Score = 33.1 bits (74), Expect = 0.076, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 27/79 (34%), Gaps = 11/79 (13%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPF-----------GDPSAFAEYVFNV 71 E +W + G++ K E I K + P+ E F Sbjct: 6 TVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEK 65 Query: 72 FDADKNGYIDFKEFICALS 90 D +++G + +EF+ A Sbjct: 66 MDRNQDGVVTIEEFLEACQ 84 >3NCG-A nrPDB Length = 486 Score = 109 bits (273), Expect = 6e-25, Method: Composition-based stats. Identities = 37/187 (19%), Positives = 77/187 (41%), Gaps = 28/187 (14%) Query: 3 KSQSKLSQDQLQDLVR--STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFG- 59 +++ KL+Q L + +T + K+L + ++ + G L++ E + Y +F Sbjct: 307 QAEKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNN-DGMLDRDELVRGYHEFMRLKG 365 Query: 60 ------------DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQL 107 + + + D D +G I++ EFI + + +++ AF++ Sbjct: 366 VDSNSLIQNEGSTIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKM 425 Query: 108 YDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLE 167 +D D +G IS E+ ++ D + + I +D NKDG++ Sbjct: 426 FDKDGSGKISTKELFKLFS------------QADSSIQMEELESIIEQVDNNKDGEVDFN 473 Query: 168 EFCEGSK 174 EF E + Sbjct: 474 EFVEMLQ 480 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 G + S+ + R+ ++ +++ +K F KD SG ++ E K++ Q Sbjct: 394 GSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKD-GSGKISTKELFKLFSQADSSIQM 452 Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSR 94 E + D +K+G +DF EF+ L R Sbjct: 453 EEL-ESIIEQVDNNKDGEVDFNEFVEMLQNFVR 484 >2E30-A nrPDB Length = 195 Score = 109 bits (273), Expect = 6e-25, Method: Composition-based stats. Identities = 43/194 (22%), Positives = 86/194 (44%), Gaps = 31/194 (15%) Query: 1 MGKSQSKLSQDQ-LQDLVRSTRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFP 57 MG S L +D+ L+++ + T F ++ + Y F +G L++ +FQ+I P Sbjct: 1 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRI-----P 55 Query: 58 FGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDK----------------L 101 + + + N F + ++F+ F+ L+ E N+K L Sbjct: 56 ELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKL 115 Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 +AF+LYDLD + IS DE+L+++ + + S +L ++ D++ D Sbjct: 116 HFAFRLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGS-------IADRTIQEADQDGD 168 Query: 162 GQLTLEEFCEGSKR 175 ++ EF + ++ Sbjct: 169 SAISFTEFVKVLEK 182 >3QRX-A nrPDB Length = 169 Score = 108 bits (269), Expect = 2e-24, Method: Composition-based stats. Identities = 37/168 (22%), Positives = 79/168 (47%), Gaps = 15/168 (8%) Query: 9 SQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYV 68 +DQ + V T K+E+++ + F D SG ++ E + + F + + Sbjct: 12 RRDQKKGRVGLTEEQKQEIREAFDLFDTD-GSGTIDAKELKVAMRAL-GFEPKKEEIKKM 69 Query: 69 FNVFDADKNGYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 + D D +G IDF+EF+ ++ + ++++ AF+L+D DN+G I+ ++ R+ Sbjct: 70 ISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKE 129 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + E+ E+ + ++ D+N D ++ +EF K+ Sbjct: 130 LG------------ENLTEEELQEMIAEADRNDDNEIDEDEFIRIMKK 165 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 31/71 (43%), Gaps = 2/71 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+ + ++ F D SG + + +++ K+ E + D + + ID Sbjct: 99 SREEILKAFRLFDDDN-SGTITIKDLRRVAKELGENLTEEELQE-MIAEADRNDDNEIDE 156 Query: 83 KEFICALSVTS 93 EFI + TS Sbjct: 157 DEFIRIMKKTS 167 >2LHI-A nrPDB Length = 176 Score = 104 bits (260), Expect = 2e-23, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 68/158 (43%), Gaps = 16/158 (10%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 T E ++ + F KD +G ++ SE + + A + N D D N Sbjct: 5 LTEEQIAEFKEAFALFDKDN-NGSISSSELATVMRSL-GLSPSEAEVNDLMNEIDVDGNH 62 Query: 79 YIDFKEFICALSVTSRG-ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 I+F EF+ +S + + +L+ AF+++D + +GLIS E+ ++ +I Sbjct: 63 QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIG-------- 114 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E + V+ + + + G++ +++F + Sbjct: 115 ----EKLTDAEVDDMLREV-SDGSGEINIQQFAALLSK 147 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 36/92 (39%), Gaps = 3/92 (3%) Query: 12 QLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNV 71 L + ++EL + +K F K+ G ++ +E + + A + + Sbjct: 71 ALMSRQLKSNDSEQELLEAFKVFDKN-GDGLISAAELKHVLTSI-GEKLTDAEVDDMLRE 128 Query: 72 FDADKNGYIDFKEFICALSVTSRGELNDKLIW 103 +D +G I+ ++F LS S K + Sbjct: 129 V-SDGSGEINIQQFAALLSKGSSTGTRRKALR 159 >1DTL-A nrPDB Length = 161 Score = 104 bits (259), Expect = 3e-23, Method: Composition-based stats. Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 17/163 (10%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDAD 75 + + T K E + + F G ++ E K+ + P E + + D D Sbjct: 9 VEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQE-MIDEVDED 67 Query: 76 KNGYIDFKEFICALSVTSR----GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 +G +DF EF+ + + + G+ ++L F+++D + +G I +E+ ++ A Sbjct: 68 GSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATG-- 125 Query: 132 VGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 E E + ++ DKN DG++ +EF E K Sbjct: 126 ----------ETITEDDIEELMKDGDKNNDGRIDYDEFLEFMK 158 Score = 53.9 bits (128), Expect = 5e-08, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 42/99 (42%), Gaps = 8/99 (8%) Query: 77 NGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 +G I KE + + + ++L D D +G + +DE L ++ K Sbjct: 33 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMK------ 86 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + + E+ ++ +F M DKN DG + LEE + Sbjct: 87 --DDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQA 123 Score = 32.7 bits (73), Expect = 0.11, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 34/80 (42%), Gaps = 13/80 (16%) Query: 98 NDKLIWAFQLYDLDN-NGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMM 156 ++ AF ++ L +G IS E+ +++ + + + + + ++ + + Sbjct: 17 KNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQ------------NPTPEELQEMIDEV 64 Query: 157 DKNKDGQLTLEEFCEGSKRD 176 D++ G + +EF R Sbjct: 65 DEDGSGTVDFDEFLVMMVRS 84 >2BEC-A nrPDB Length = 202 Score = 103 bits (257), Expect = 4e-23, Method: Composition-based stats. Identities = 47/195 (24%), Positives = 79/195 (40%), Gaps = 32/195 (16%) Query: 1 MGKSQSKLSQ-DQLQDLVRSTRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFP 57 MG S + + R T F + L + + F G+L++ + Q+I Sbjct: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAV- 59 Query: 58 FGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND-----------------K 100 + + + F D + +DF F+ L+ E D K Sbjct: 60 ----NPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNK 115 Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNK 160 L +AFQLYDLD +G IS EML++ + MVG V E+ E ++ D++ Sbjct: 116 LHYAFQLYDLDRDGKISRHEMLQV---LRLMVGVQVT----EEQLENIADRTVQEADEDG 168 Query: 161 DGQLTLEEFCEGSKR 175 DG ++ EF + ++ Sbjct: 169 DGAVSFVEFTKSLEK 183 >2L1W-A nrPDB Length = 149 Score = 102 bits (255), Expect = 8e-23, Method: Composition-based stats. Identities = 33/156 (21%), Positives = 66/156 (42%), Gaps = 15/156 (9%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 + + ++ + F KD G + E + + + + + DAD NG Sbjct: 4 LSEEQIVDFKEAFGLFDKD-GDGCITVEELATVIRSLDQNPTEEELQD-MISEVDADGNG 61 Query: 79 YIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 I+F EF+ ++ + + ++L AF+++D D NG IS E+ ++ + Sbjct: 62 TIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLG-------- 113 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E ++ V ++ D + DGQ+ EEF + Sbjct: 114 ----EKLTDEEVEQMIKEADLDGDGQVNYEEFVKMM 145 Score = 59.6 bits (143), Expect = 7e-10, Method: Composition-based stats. Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 1/107 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++ELQ D +G + EF + + D + F VFD D+NGYI Sbjct: 44 TEEELQDMISEVDAD-GNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISA 102 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIY 129 E + ++++ + DLD +G ++Y+E ++++ + Sbjct: 103 SELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTVR 149 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 35/74 (47%), Gaps = 12/74 (16%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 AF L+D D +G I+ +E+ ++ ++ D++ E+ + + + +D + + Sbjct: 13 KEAFGLFDKDGDGCITVEELATVIRSL------------DQNPTEEELQDMISEVDADGN 60 Query: 162 GQLTLEEFCEGSKR 175 G + +EF + Sbjct: 61 GTIEFDEFLSLMAK 74 >4DS7-A nrPDB Length = 147 Score = 102 bits (253), Expect = 1e-22, Method: Composition-based stats. Identities = 33/160 (20%), Positives = 69/160 (43%), Gaps = 16/160 (10%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 T E ++ + F KD SG ++ SE + + A + N D D Sbjct: 3 QNLTEEQIAEFKEAFALFDKDN-SGSISASELATVMRSL-GLSPSEAEVADLMNEIDVDG 60 Query: 77 NGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 N I+F EF+ +S + + +L+ AF+++D + +GLIS E+ ++ +I Sbjct: 61 NHAIEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIG------ 114 Query: 136 VKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E + V+++ + + G++ +++F + Sbjct: 115 ------EKLTDAEVDEMLREV-SDGSGEINIKQFAALLSK 147 >4JWQ-A nrPDB Length = 199 Score = 99.7 bits (247), Expect = 7e-22, Method: Composition-based stats. Identities = 42/159 (26%), Positives = 78/159 (49%), Gaps = 13/159 (8%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 +S +D ++L+ + + + G++ K++ +K + + + + + D+D Sbjct: 50 QQSNDYDLQQLKTVF-LYLDEDGKGNITKNQLKKGLENSGLKLPQN--FDVLLDQIDSDG 106 Query: 77 NGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 +G ID+ EF+ A R L+ KLI+ AF+++D+DN+G I+ E+ I+ K Sbjct: 107 SGRIDYTEFLAA--ALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGSIT 164 Query: 136 VKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 K V K+ +DKN DG++ EFCE K Sbjct: 165 QKDVNQ-------VKKMIQEVDKNNDGKIDFYEFCEMMK 196 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 27/76 (35%), Gaps = 5/76 (6%) Query: 21 RFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPS----AFAEYVFNVFDADK 76 KK + ++ F D G + +E I G + + + D + Sbjct: 124 HLSKKLIYCAFRVFDVDN-DGEITTAELAHILYNGNKKGSITQKDVNQVKKMIQEVDKNN 182 Query: 77 NGYIDFKEFICALSVT 92 +G IDF EF + + Sbjct: 183 DGKIDFYEFCEMMKLK 198 Score = 35.0 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 12/98 (12%), Positives = 33/98 (33%), Gaps = 13/98 (13%) Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTP 145 + ++ S +L F D D G I+ +++ + ++ + Sbjct: 45 MTIIAQQSNDYDLQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNF--------- 95 Query: 146 EKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSAL 183 + + + +D + G++ EF + + L Sbjct: 96 ----DVLLDQIDSDGSGRIDYTEFLAAALDRKHLSKKL 129 >1TOP-A nrPDB Length = 162 Score = 98.9 bits (245), Expect = 1e-21, Method: Composition-based stats. Identities = 32/172 (18%), Positives = 68/172 (39%), Gaps = 18/172 (10%) Query: 6 SKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFA 65 + ++ Q + + E + + F D G ++ E + + Sbjct: 1 ASMTDQQAEARAFLSEEMIAEFKAAFDMFDADGG-GDISTKELGTVMRMLGQNP-TKEEL 58 Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSR----GELNDKLIWAFQLYDLDNNGLISYDEM 121 + + D D +G IDF+EF+ + + G+ ++L F+++D + +G I +E+ Sbjct: 59 DAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEEL 118 Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 I+ A E E+ + + DKN DG++ +EF + Sbjct: 119 GEILRATG------------EHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMM 158 >1LKJ-A nrPDB Length = 146 Score = 98.9 bits (245), Expect = 1e-21, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 68/158 (43%), Gaps = 16/158 (10%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 T E ++ + F KD +G ++ SE + + A + N D D N Sbjct: 4 LTEEQIAEFKEAFALFDKDN-NGSISSSELATVMRSL-GLSPSEAEVNDLMNEIDVDGNH 61 Query: 79 YIDFKEFICALSVTSRG-ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 I+F EF+ +S + + +L+ AF+++D + +GLIS E+ ++ +I Sbjct: 62 QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIG-------- 113 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E + V+ + + + G++ +++F + Sbjct: 114 ----EKLTDAEVDDMLREV-SDGSGEINIQQFAALLSK 146 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 33/79 (41%), Gaps = 3/79 (3%) Query: 12 QLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNV 71 L + ++EL + +K F K+ G ++ +E + + A + + Sbjct: 70 ALMSRQLKSNDSEQELLEAFKVFDKN-GDGLISAAELKHVLTSI-GEKLTDAEVDDMLRE 127 Query: 72 FDADKNGYIDFKEFICALS 90 +D +G I+ ++F LS Sbjct: 128 V-SDGSGEINIQQFAALLS 145 >3O4Y-A nrPDB Length = 196 Score = 97.8 bits (242), Expect = 3e-21, Method: Composition-based stats. Identities = 40/159 (25%), Positives = 79/159 (49%), Gaps = 13/159 (8%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 +S +D ++L+ + ++ G++ K + +K ++ P+ + + + D+D Sbjct: 47 QQSNDYDVQKLKAAFLHLDEEGK-GNITKLQLRKGLERSGLMLPPN--FDLLLDQIDSDG 103 Query: 77 NGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 +G ID+ EF+ A R +L+ KLI+ AF+++D+DN+G I+ E+ ++ K Sbjct: 104 SGNIDYTEFLAA--AIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNGNKRGNIT 161 Query: 136 VKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 + V K+ +DKN DG++ EF E K Sbjct: 162 ERDVNQ-------VKKMIREVDKNGDGKIDFYEFSEMMK 193 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 30/77 (38%), Gaps = 5/77 (6%) Query: 21 RFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSA----FAEYVFNVFDADK 76 + KK + ++ F D G + +E + G+ + + + D + Sbjct: 121 QLSKKLIYCAFRVFDVDN-DGEITTAELAHVLFNGNKRGNITERDVNQVKKMIREVDKNG 179 Query: 77 NGYIDFKEFICALSVTS 93 +G IDF EF + +T Sbjct: 180 DGKIDFYEFSEMMKLTL 196 Score = 33.5 bits (75), Expect = 0.052, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 31/88 (35%), Gaps = 13/88 (14%) Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTP 145 + ++ S KL AF D + G I+ ++ + ++ M+ Sbjct: 42 MTIIAQQSNDYDVQKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNF--------- 92 Query: 146 EKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 + + + +D + G + EF + Sbjct: 93 ----DLLLDQIDSDGSGNIDYTEFLAAA 116 >2AAO-A nrPDB Length = 166 Score = 97.8 bits (242), Expect = 3e-21, Method: Composition-based stats. Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 19/175 (10%) Query: 3 KSQSKLSQDQLQDLVRSTRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGD 60 + +K + L+ + S ++E+ + F SG + E + K+ Sbjct: 4 SAMNKFKKMALRVIAES--LSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLK 61 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 S + + D D +G ID+KEFI A ++ E D L AF +D D +G I+ DE Sbjct: 62 ESEILD-LMQAADVDNSGTIDYKEFIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDE 120 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + + E+ + R+ ++ +D++ DG++ EF ++ Sbjct: 121 LQQAC--------------EEFGVEDVRIEELMRDVDQDNDGRIDYNEFVAMMQK 161 >1S6I-A nrPDB Length = 188 Score = 97.4 bits (241), Expect = 3e-21, Method: Composition-based stats. Identities = 36/159 (22%), Positives = 68/159 (42%), Gaps = 16/159 (10%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 R + + L++ +K D SG + E + K+ S + + + D DK Sbjct: 2 ERLSEEEIGGLKELFKMIDTDN-SGTITFDELKDGLKRVGSELMESEIKD-LMDAADIDK 59 Query: 77 NGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 +G ID+ EFI A ++ E + L+ AF +D D +G I+ DE+ + Sbjct: 60 SGTIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACK---------- 109 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 D + ++ + +D++ DGQ+ EF ++ Sbjct: 110 ----DFGLDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRK 144 >2TN4-A nrPDB Length = 159 Score = 96.6 bits (239), Expect = 5e-21, Method: Composition-based stats. Identities = 31/167 (18%), Positives = 64/167 (38%), Gaps = 18/167 (10%) Query: 11 DQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFN 70 Q + + E + + F D G ++ E + + + + Sbjct: 3 QQAEARSYLSEEMIAEFKAAFDMFDADGG-GDISVKELGTVMRML-GQTPTKEELDAIIE 60 Query: 71 VFDADKNGYIDFKEFICALSVTSR----GELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 D D +G IDF+EF+ + + G+ ++L F+++D + +G I +E+ I Sbjct: 61 EVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFR 120 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 A E ++ + + DKN DG++ +EF + Sbjct: 121 ASG------------EHVTDEEIESLMKDGDKNNDGRIDFDEFLKMM 155 >3KF9-A nrPDB Length = 149 Score = 96.6 bits (239), Expect = 6e-21, Method: Composition-based stats. Identities = 34/159 (21%), Positives = 73/159 (45%), Gaps = 15/159 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 T K+E+++ + F D SG ++ E + + F + + D D + Sbjct: 1 GLTEEQKQEIREAFDLFDTD-GSGTIDAKELKVAMRAL-GFEPKKEEIKKMIADIDKDGS 58 Query: 78 GYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G IDF+EF+ ++ + ++++ AF+L+D D G IS+ + R+ + Sbjct: 59 GTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELG------- 111 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E+ ++ + ++ + D++ DG++ EEF K+ Sbjct: 112 -----ENMTDEELQEMIDEADRDGDGEVNEEEFFRIMKK 145 Score = 35.0 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+ + ++ F D +G ++ +++ K+ E + + D D +G ++ Sbjct: 79 SREEIMKAFRLFDDD-ETGKISFKNLKRVAKELGENMTDEELQE-MIDEADRDGDGEVNE 136 Query: 83 KEFICALSVTS 93 +EF + TS Sbjct: 137 EEFFRIMKKTS 147 >3K21-A nrPDB Length = 191 Score = 94.3 bits (233), Expect = 3e-20, Method: Composition-based stats. Identities = 41/159 (25%), Positives = 78/159 (49%), Gaps = 13/159 (8%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 +S +D ++L+ + + G++ K + +K ++ + + + + D+D Sbjct: 44 QQSNDYDVEKLKSTF-LVLDEDGKGYITKEQLKKGLEKDGLKLPYN--FDLLLDQIDSDG 100 Query: 77 NGYIDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 +G ID+ EFI A R +L+ KLI+ AF+++D+DN+G I+ E+ I+ K Sbjct: 101 SGKIDYTEFIAA--ALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGNIT 158 Query: 136 VKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 + RV ++ +DKN DG++ EF E K Sbjct: 159 QRDV-------NRVKRMIRDVDKNNDGKIDFHEFSEMMK 190 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 13/98 (13%), Positives = 35/98 (35%), Gaps = 13/98 (13%) Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTP 145 + ++ S +KL F + D D G I+ +++ + ++ + Sbjct: 39 MTIIAQQSNDYDVEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNF--------- 89 Query: 146 EKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSAL 183 + + + +D + G++ EF + + L Sbjct: 90 ----DLLLDQIDSDGSGKIDYTEFIAAALDRKQLSKKL 123 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 29/75 (38%), Gaps = 5/75 (6%) Query: 21 RFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPS----AFAEYVFNVFDADK 76 + KK + ++ F D G + +E I G+ + + + D + Sbjct: 118 QLSKKLIYCAFRVFDVDN-DGEITTAELAHILYNGNKKGNITQRDVNRVKRMIRDVDKNN 176 Query: 77 NGYIDFKEFICALSV 91 +G IDF EF + + Sbjct: 177 DGKIDFHEFSEMMKL 191 >2LMV-A nrPDB Length = 148 Score = 93.9 bits (232), Expect = 4e-20, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 64/156 (41%), Gaps = 15/156 (9%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDAD 75 + T E + + F K+ +G + E + + A + + + + Sbjct: 1 MSELTEEQIAEFKDAFVQFDKE-GTGKIATRELGTLMRTLGQNP-TEAELQDLIAEAENN 58 Query: 76 KNGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGS 134 NG ++F EF ++ R + +++ AF+++D D +G IS E+ ++ + Sbjct: 59 NNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLG----- 113 Query: 135 MVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 E ++ ++++ D + DG + EEF Sbjct: 114 -------EKVTDEEIDEMIREADFDGDGMINYEEFV 142 Score = 58.1 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + ELQ ++ +G LN +EF I + D F +FD D +G+I Sbjct: 44 TEAELQDLIAE-AENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISP 102 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 E + ++++ + D D +G+I+Y+E + ++ Sbjct: 103 AELRFVMINLGEKVTDEEIDEMIREADFDGDGMINYEEFVWMI 145 Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+++ +K F +D G ++ +E + + + + D D +G I++ Sbjct: 81 TEEEMREAFKIFDRD-GDGFISPAELRFVMINL-GEKVTDEEIDEMIREADFDGDGMINY 138 Query: 83 KEFICALSVT 92 +EF+ +S Sbjct: 139 EEFVWMISQK 148 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 29/76 (38%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF +D + G I+ E+ ++ + + + E + + + N Sbjct: 11 EFKDAFVQFDKEGTGKIATRELGTLMRTLGQ------------NPTEAELQDLIAEAENN 58 Query: 160 KDGQLTLEEFCEGSKR 175 +GQL EFC + Sbjct: 59 NNGQLNFTEFCGIMAK 74 >5D43-A nrPDB Length = 178 Score = 93.2 bits (230), Expect = 7e-20, Method: Composition-based stats. Identities = 31/159 (19%), Positives = 72/159 (45%), Gaps = 15/159 (9%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 T K+E+++ + F D SG ++ E + + F + + + D + Sbjct: 24 ELTEDQKQEVREAFDLFDSD-GSGTIDVKELKVAMRAL-GFEPRKEEMKKMISEVDKEAT 81 Query: 78 GYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G I F +F+ ++ + ++++ AF+L+D D G IS+ + R+ + + Sbjct: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELG------- 134 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E ++ + ++ + D++ DG++ EEF + K+ Sbjct: 135 -----ESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 >2GGM-A nrPDB Length = 172 Score = 90.8 bits (224), Expect = 3e-19, Method: Composition-based stats. Identities = 31/176 (17%), Positives = 78/176 (44%), Gaps = 18/176 (10%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 M S + +L T K+E+++ + F D +G ++ E + + F Sbjct: 10 MASSSQRKRMSPKPEL---TEEQKQEIREAFDLFDAD-GTGTIDVKELKVAMRAL-GFEP 64 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRG-ELNDKLIWAFQLYDLDNNGLISYD 119 + + + D + G ++F +F+ ++ + ++++ AF+L+D D G IS+ Sbjct: 65 KKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFK 124 Query: 120 EMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + R+ + E+ ++ + ++ + D++ DG+++ +EF K+ Sbjct: 125 NLKRVAKELG------------ENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKK 168 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 K+E+ + +K F D +G ++ +++ K+ E + + D D +G + Sbjct: 102 TKEEILKAFKLFDDD-ETGKISFKNLKRVAKELGENLTDEELQE-MIDEADRDGDGEVSE 159 Query: 83 KEFICALSVTS 93 +EF+ + TS Sbjct: 160 QEFLRIMKKTS 170 >2LHH-A nrPDB Length = 128 Score = 90.5 bits (223), Expect = 4e-19, Method: Composition-based stats. Identities = 28/115 (24%), Positives = 55/115 (47%), Gaps = 3/115 (2%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 T E ++ + F KD +G ++ SE + + A + N D D N Sbjct: 4 LTEEQIAEFKEAFALFDKDN-NGSISSSELATVMRSL-GLSPSEAEVNDLMNEIDVDGNH 61 Query: 79 YIDFKEFICALSVTSRG-ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 I+F EF+ +S + + +L+ AF+++D + +GLIS E+ ++ +I + + Sbjct: 62 QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKL 116 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 39/110 (35%), Gaps = 11/110 (10%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 A + F +FD D NG I E + ++ D+D N I + E L Sbjct: 10 AEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFL 69 Query: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEG 172 ++ + E+ + + F + DKN DG ++ E Sbjct: 70 ALMS-----------RQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHV 108 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 39/96 (40%), Gaps = 19/96 (19%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D DNNG IS E+ ++ ++ E VN + N +D + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGL------------SPSEAEVNDLMNEIDVD 58 Query: 160 KDGQLTLEEFCEGSKR-------DPTIVSALSLYDG 188 + Q+ EF R + ++ A ++D Sbjct: 59 GNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDK 94 Score = 34.2 bits (77), Expect = 0.037, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 25/80 (31%), Gaps = 1/80 (1%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 + E+ D + SEF + + D F VFD + +G I Sbjct: 44 SEAEVNDLMNEIDVDGNH-QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISA 102 Query: 83 KEFICALSVTSRGELNDKLI 102 E L+ + +L Sbjct: 103 AELKHVLTSIGEKLTDAELE 122 Score = 26.5 bits (57), Expect = 6.5, Method: Composition-based stats. Identities = 8/45 (17%), Positives = 19/45 (42%), Gaps = 1/45 (2%) Query: 12 QLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFF 56 L + ++EL + +K F K+ G ++ +E + + Sbjct: 70 ALMSRQLKSNDSEQELLEAFKVFDKN-GDGLISAAELKHVLTSIG 113 >4MVF-A nrPDB Length = 506 Score = 90.1 bits (222), Expect = 5e-19, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 57/152 (37%), Gaps = 13/152 (8%) Query: 26 ELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 E+ F SG L+ E K+ + V D++ +G I + Sbjct: 358 EINNLRNIFIALDVDNSGTLSSQEILDGLKKI-GYQKIPPDIHQVLRDIDSNASGQIHYT 416 Query: 84 EFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDED 143 +F+ A + + F+ +D+D NG IS +E+ RI + + Sbjct: 417 DFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFG----------RDDIENP 466 Query: 144 TPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 +K ++ + +D N DG++ EF + Sbjct: 467 LIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSK 498 Score = 46.2 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 2/78 (2%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIY-KQFFPFGDPSAFAEYVFNVFDA 74 + + T KKE+ FF +G ++ E ++I+ + + + D Sbjct: 423 IDKQTYL-KKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLIDKAIDSLLQEVDL 481 Query: 75 DKNGYIDFKEFICALSVT 92 + +G IDF EF+ +S Sbjct: 482 NGDGEIDFHEFMLMMSKL 499 Score = 32.7 bits (73), Expect = 0.11, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 31/83 (37%), Gaps = 12/83 (14%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 + L F D+DN+G +S E+L + I ++++ +D Sbjct: 360 NNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPP------------DIHQVLRDIDS 407 Query: 159 NKDGQLTLEEFCEGSKRDPTIVS 181 N GQ+ +F + T + Sbjct: 408 NASGQIHYTDFLAATIDKQTYLK 430 >5ZOR-A nrPDB Length = 149 Score = 88.9 bits (219), Expect = 1e-18, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 66/153 (43%), Gaps = 14/153 (9%) Query: 22 FDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYID 81 +++++ + F D SG ++ E K P E + + NG I+ Sbjct: 4 LTDEQIREAFNLFDAD-GSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIE 62 Query: 82 FKEFICAL-SVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPE 140 + EF + S ++ + ++++ AFQL+DLD G IS+ + + + Sbjct: 63 YGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLG----------- 111 Query: 141 DEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E+ + + ++ D++ DG+++ EEF Sbjct: 112 -ENPGDDVLQEMIAEADEDGDGEVSFEEFKSVM 143 Score = 67.7 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 12/114 (10%) Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGEL-NDKLIWAFQLYDLDNNGLISYDE 120 FN+FDAD +G ID +E A+ G+L D++ + + + NGLI Y E Sbjct: 6 DEQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYGE 65 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 R+V + +D+PE+ V K F + D +K G+++ E +K Sbjct: 66 FERMVKS----------RMAQKDSPEE-VLKAFQLFDLDKKGKISFANLKEVAK 108 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 37/102 (36%), Gaps = 18/102 (17%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 ++++ AF L+D D +G I +EM + + D P V + Sbjct: 1 MAALTDEQIREAFNLFDADGSGAIDAEEMALAMKGLGF-----------GDLPRDEVERT 49 Query: 153 FNMMDKNKDGQLTLEEFCEGSKRD-------PTIVSALSLYD 187 M+ N +G + EF K ++ A L+D Sbjct: 50 VRSMNTNANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFD 91 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 10/66 (15%), Positives = 28/66 (42%), Gaps = 2/66 (3%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 +E+ + ++ F D G ++ + +++ + + + D D +G + F+E Sbjct: 81 EEVLKAFQLFDLD-KKGKISFANLKEV-AKLLGENPGDDVLQEMIAEADEDGDGEVSFEE 138 Query: 85 FICALS 90 F + Sbjct: 139 FKSVMM 144 >3PM8-A nrPDB Length = 197 Score = 85.1 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 54/143 (37%), Gaps = 11/143 (7%) Query: 35 FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSR 94 SG L+ E K+ + V D++ +G I + +F+ A Sbjct: 66 LDVDNSGTLSSQEILDGLKKI-GYQKIPPDIHQVLRDIDSNASGQIHYTDFLAATIDKQT 124 Query: 95 GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFN 154 + + F+ +D+D NG IS +E+ RI + + +K ++ + Sbjct: 125 YLKKEVCLIPFKFFDIDGNGKISVEELKRIFG----------RDDIENPLIDKAIDSLLQ 174 Query: 155 MMDKNKDGQLTLEEFCEGSKRDP 177 +D N DG++ EF + Sbjct: 175 EVDLNGDGEIDFHEFMLMMSKKK 197 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 30/71 (42%), Gaps = 1/71 (1%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIY-KQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 KKE+ FF +G ++ E ++I+ + + + D + +G IDF Sbjct: 127 KKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDF 186 Query: 83 KEFICALSVTS 93 EF+ +S Sbjct: 187 HEFMLMMSKKK 197 Score = 30.4 bits (67), Expect = 0.43, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 31/83 (37%), Gaps = 12/83 (14%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 + L F D+DN+G +S E+L + I ++++ +D Sbjct: 57 NNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPP------------DIHQVLRDIDS 104 Query: 159 NKDGQLTLEEFCEGSKRDPTIVS 181 N GQ+ +F + T + Sbjct: 105 NASGQIHYTDFLAATIDKQTYLK 127 >2OBH-A nrPDB Length = 143 Score = 84.7 bits (208), Expect = 2e-17, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 73/157 (46%), Gaps = 15/157 (9%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 T K+E+++ + F D +G ++ E + + F + + + D + G Sbjct: 1 TEEQKQEIREAFDLFDAD-GTGTIDVKELKVAMRAL-GFEPKKEEIKKMISEIDKEGTGK 58 Query: 80 IDFKEFICALSVTSRG-ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKL 138 ++F +F+ ++ + ++++ AF+L+D D G IS+ + R+ + Sbjct: 59 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELG--------- 109 Query: 139 PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E+ ++ + ++ + D++ DG+++ +EF K+ Sbjct: 110 ---ENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKK 143 >2LAP-A nrPDB Length = 167 Score = 84.3 bits (207), Expect = 3e-17, Method: Composition-based stats. Identities = 33/180 (18%), Positives = 68/180 (37%), Gaps = 18/180 (10%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 MG ++ + + +EL++ ++ F KD G++N + + Sbjct: 1 MGNCVKYPLRNLSRKDRSLRPEEIEELREAFREFDKD-KDGYINCRDLGNCMRTMGYMPT 59 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND-----KLIWAFQLYDLDNNGL 115 E + + + G++DF +F+ + E D +L AF+ +D + +G Sbjct: 60 EMELIE-LSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGE 118 Query: 116 ISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 IS E+ + + + + +I +D N DG++ EEF R Sbjct: 119 ISTSELREAMRKLLGH-----------QVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR 167 >2BL0-C nrPDB Length = 142 Score = 83.5 bits (205), Expect = 5e-17, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 58/152 (38%), Gaps = 16/152 (10%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 E ++ ++ F + +G + K Q + KQF +P+AF E +FN DA NG I F Sbjct: 4 QVSEFKEAFELFDSE-RTGFITKEGLQTVLKQFGVRVEPAAFNE-MFNEADATGNGKIQF 61 Query: 83 KEFICALSVTSRGELNDK-LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPED 141 EF+ + + ++ L AF+ +D + G I + + + + Sbjct: 62 PEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNLGDRLKPHEFAEFL 121 Query: 142 EDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 T + GQ+ + F Sbjct: 122 GITETE-------------KGQIRYDNFINTM 140 Score = 39.6 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 29/76 (38%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF+L+D + G I+ + + ++ V N++FN D Sbjct: 7 EFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAF------------NEMFNEADAT 54 Query: 160 KDGQLTLEEFCEGSKR 175 +G++ EF R Sbjct: 55 GNGKIQFPEFLSMMGR 70 >2HF5-A nrPDB Length = 68 Score = 80.4 bits (197), Expect = 5e-16, Method: Composition-based stats. Identities = 21/68 (30%), Positives = 38/68 (55%), Gaps = 1/68 (1%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSR-GELNDKLIWAFQLYDLDNNGLISYDEM 121 A + + N DAD NG IDF EF+ ++ + + +++ AF+++D D NG IS E+ Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 Query: 122 LRIVDAIY 129 ++ + Sbjct: 61 RHVMTNLG 68 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 21/58 (36%) Query: 36 KDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTS 93 +G ++ EF + + D F VFD D NGYI E ++ Sbjct: 11 DADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 68 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 28/74 (37%), Gaps = 11/74 (14%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 +L D D NG I + E L ++ K S E+ + + F + DK+ Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDS-----------EEEIREAFRVFDKD 50 Query: 160 KDGQLTLEEFCEGS 173 +G ++ E Sbjct: 51 GNGYISAAELRHVM 64 Score = 26.9 bits (58), Expect = 6.0, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 18/48 (37%), Gaps = 7/48 (14%) Query: 148 RVNKIFNMMDKNKDGQLTLEEFCEGSKR-------DPTIVSALSLYDG 188 + + N +D + +G + EF R + I A ++D Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDK 49 Score = 26.1 bits (56), Expect = 9.7, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFF 56 ++E+++ ++ F KD +G+++ +E + + Sbjct: 36 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLG 68 >2JNF-A nrPDB Length = 158 Score = 78.1 bits (191), Expect = 2e-15, Method: Composition-based stats. Identities = 35/164 (21%), Positives = 65/164 (39%), Gaps = 18/164 (10%) Query: 15 DLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDA 74 D+ + + K L+ ++ F SG ++ + I + + + + FD Sbjct: 3 DVSKLSSNQVKLLETAFRDFETPEGSGRVSTDQIGIIL-EVLGIQQTKSTIRQLIDEFDP 61 Query: 75 DKNGYIDFKEFICALSVT-----SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIY 129 NG IDF F + + ++ +L AF+LYD + NG IS D M I+ + Sbjct: 62 FGNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAEL- 120 Query: 130 KMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 DE + ++ + + +D + G + EEF Sbjct: 121 -----------DETLSSEDLDAMIDEIDADGSGTVDFEEFMGVM 153 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 40/108 (37%), Gaps = 5/108 (4%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEY----VFNVFDADKNG 78 K ++Q F +G ++ F+ I +F + F ++D + NG Sbjct: 48 TKSTIRQLIDEFDP-FGNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNG 106 Query: 79 YIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 YI L+ ++ L D D +G + ++E + ++ Sbjct: 107 YISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVMT 154 >3E3R-A nrPDB Length = 204 Score = 76.6 bits (187), Expect = 6e-15, Method: Composition-based stats. Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 15/166 (9%) Query: 27 LQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFI 86 L ++++ +D S L+ EF++ + D A AE V +D + +G +D +EF+ Sbjct: 39 LARFFRQLDRD-GSRSLDADEFRQGLAKLGLVLD-QAEAEGVCRKWDRNGSGTLDLEEFL 96 Query: 87 CALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPE 146 AL + AF D +G+++ D++ + + K+ E T + Sbjct: 97 RALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSG-----RAHPKVRSGEWTED 151 Query: 147 KRVNKIFNMMD-KNKDGQLTLEEFCE-------GSKRDPTIVSALS 184 + + + + D KDGQ+TL EF + D V+ ++ Sbjct: 152 EVLRRFLDNFDSSEKDGQVTLAEFQDYYSGVSASMNTDEEFVAMMT 197 Score = 27.3 bits (59), Expect = 4.6, Method: Composition-based stats. Identities = 9/64 (14%), Positives = 24/64 (37%), Gaps = 1/64 (1%) Query: 113 NGLISYDEM-LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 +GL+ + + M + + + + + F +D++ L +EF + Sbjct: 2 SGLVPRGPLGSHMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDRDGSRSLDADEFRQ 61 Query: 172 GSKR 175 G + Sbjct: 62 GLAK 65 >3FWC-A nrPDB Length = 161 Score = 76.2 bits (186), Expect = 8e-15, Method: Composition-based stats. Identities = 33/174 (18%), Positives = 67/174 (38%), Gaps = 17/174 (9%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 M K++S L L K+E+ + + F + G L+ E + K F Sbjct: 1 MSKNRSSLQSGPLN--SELLEEQKQEIYEAFSLFDMNN-DGFLDYHELKVAMKAL-GFEL 56 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVT-SRGELNDKLIWAFQLYDLDNNGLISYD 119 P + + +D++ + + +F + + + D++ AFQL+D D+ G IS Sbjct: 57 PKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIK 116 Query: 120 EMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 + R+ + E ++ + + D + DG++ EF Sbjct: 117 NLRRVAKELG------------ETLTDEELRAMIEEFDLDGDGEINENEFIAIC 158 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 39/107 (36%), Gaps = 1/107 (0%) Query: 21 RFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYI 80 K+E+ + + + +F + + DP + F +FD D G I Sbjct: 55 ELPKREILDLIDEYDSEGRH-LMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKI 113 Query: 81 DFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 K +++L + +DLD +G I+ +E + I Sbjct: 114 SIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAICTD 160 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 49/132 (37%), Gaps = 11/132 (8%) Query: 44 NKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW 103 N+S Q + F++FD + +G++D+ E A+ +++ Sbjct: 4 NRSSLQSGPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILD 63 Query: 104 AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ 163 YD + L+ YD+ ++ + P + + F + D + G+ Sbjct: 64 LIDEYDSEGRHLMKYDDFYIVMG-----------EKILKRDPLDEIKRAFQLFDDDHTGK 112 Query: 164 LTLEEFCEGSKR 175 ++++ +K Sbjct: 113 ISIKNLRRVAKE 124 >2M29-A nrPDB Length = 171 Score = 75.4 bits (184), Expect = 1e-14, Method: Composition-based stats. Identities = 32/148 (21%), Positives = 56/148 (37%), Gaps = 18/148 (12%) Query: 28 QQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFIC 87 Q ++ F D G++ E + E V G++DF+EF+ Sbjct: 31 QAAFEEFDTD-QDGYIGYRELGDCMRTLGYMPTEMELLE-VSQHVKMRMGGFVDFEEFVE 88 Query: 88 ALSVTSRGELND-----KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDE 142 +S R E +L AF+ +D D +G I+ E+ + A+ +L Sbjct: 89 LISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTEL---- 144 Query: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 +++ MD N DG + +EF Sbjct: 145 -------DEMLREMDLNGDGTIDFDEFV 165 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 +EL+ ++ F KD G + +E ++ + + D + +G IDF E Sbjct: 105 RELRIAFREFDKD-RDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTIDFDE 163 Query: 85 FICALS 90 F+ LS Sbjct: 164 FVMMLS 169 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 25/72 (34%), Gaps = 12/72 (16%) Query: 103 WAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDG 162 AF+ +D D +G I Y E+ + + M M L + V G Sbjct: 32 AAFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVS-----QHVKMRMG-------G 79 Query: 163 QLTLEEFCEGSK 174 + EEF E Sbjct: 80 FVDFEEFVELIS 91 >4WPX-A nrPDB Length = 177 Score = 72.7 bits (177), Expect = 8e-14, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 64/176 (36%), Gaps = 25/176 (14%) Query: 14 QDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFD 73 +D + + K + + ++ F + G L+ EF+ + + + + Sbjct: 15 EDYNKLSDEQKTRISEAFELFDSN-KDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQ 73 Query: 74 ADKNGYID------FKEFICALSVTSRGEL------NDKLIWAFQLYDLDNNGLISYDEM 121 N D +++F A + G L D+L AF+L+D+D G+I+ D++ Sbjct: 74 RPANWPHDQECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDL 133 Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDP 177 ++ + + P+ + + D N G + +EF Sbjct: 134 RKVCQQVGN------------NIPDADIQAMIEEFDSNGKGGVDEDEFLRLMMSKK 177 >5MWC-D nrPDB Length = 311 Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 39/88 (44%), Gaps = 12/88 (13%) Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTP 145 + A S+T+ ++L F+ +D D +G I +E I+ E Sbjct: 138 VMANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIRLTG------------EQLT 185 Query: 146 EKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 ++ ++IF D +K+G++ +EF + Sbjct: 186 DEDPDEIFGDSDTDKNGRIDFDEFLKMV 213 Score = 69.3 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 32/71 (45%) Query: 58 FGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLIS 117 F FD D +G+ID +EF + +T ++ F D D NG I Sbjct: 146 MVPSEEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRID 205 Query: 118 YDEMLRIVDAI 128 +DE L++V+ + Sbjct: 206 FDEFLKMVENV 216 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++EL + ++ F KD G +++ EF I + + +F D DKNG IDF Sbjct: 149 SEEELSECFRTFDKD-GDGFIDREEFGGIIR-LTGEQLTDEDPDEIFGDSDTDKNGRIDF 206 Query: 83 KEFICAL 89 EF+ + Sbjct: 207 DEFLKMV 213 >5E37-A nrPDB Length = 356 Score = 71.2 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 35/176 (19%), Positives = 69/176 (39%), Gaps = 25/176 (14%) Query: 23 DKKELQQWYKGFF--KDCPSGHLNKSEFQKIYK--------QFFPFGDPSAFAEYVFNVF 72 K ++++ + F +GH+++ E + + + P E + Sbjct: 24 SKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQY 83 Query: 73 DADKNGYIDFKEFICAL--SVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 D +K+G I F+EF + + G L + AF+ D NG I E+ ++ ++ Sbjct: 84 DVNKDGVISFEEFKQIIYDGLLLEGTLAE-YESAFKAVDKSGNGTIGATELSKLFASLGN 142 Query: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLY 186 V + EK V+ + M DK+ GQ+ EF + + ++ Y Sbjct: 143 PV-----------SLEKLVD-LMQMYDKDDSGQIEFPEFLLMFRNSLLDLKDMTTY 186 Score = 65.8 bits (159), Expect = 9e-12, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 48/103 (46%), Gaps = 4/103 (3%) Query: 85 FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDT 144 F + S+ ++ ++L F++ D+D NG I +E+ ++++ M V + Sbjct: 16 FEGLMDDASKAKM-EELERRFKMADVDGNGHIDREELRNLLES---MESGEVYMMSQHWL 71 Query: 145 PEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYD 187 PE + + D NKDG ++ EEF + + L+ Y+ Sbjct: 72 PEDELERCMEQYDVNKDGVISFEEFKQIIYDGLLLEGTLAEYE 114 Score = 61.6 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 49/120 (40%), Gaps = 2/120 (1%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 + EL++ + + + G ++ EF++I A E F D NG I Sbjct: 73 EDELERCMEQYDVN-KDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGAT 131 Query: 84 EFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV-DAIYKMVGSMVKLPEDE 142 E + +KL+ Q+YD D++G I + E L + +++ + + DE Sbjct: 132 ELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEFPEFLLMFRNSLLDLKDMTTYMTLDE 191 Score = 59.6 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 32/141 (22%), Positives = 59/141 (41%), Gaps = 26/141 (18%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGEL---------NDKLIWAFQLYDLDNN 113 E F + D D NG+ID +E L GE+ D+L + YD++ + Sbjct: 29 EELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVNKD 88 Query: 114 GLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE-- 171 G+IS++E +I+ + G++ + F +DK+ +G + E + Sbjct: 89 GVISFEEFKQIIYDGLLLEGTLAEY-----------ESAFKAVDKSGNGTIGATELSKLF 137 Query: 172 GSKRDP----TIVSALSLYDG 188 S +P +V + +YD Sbjct: 138 ASLGNPVSLEKLVDLMQMYDK 158 Score = 27.3 bits (59), Expect = 4.5, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 20/57 (35%) Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPT 178 R V + + + + + + + F M D + +G + EE + + Sbjct: 4 ARSVRVVPRAATFEGLMDDASKAKMEELERRFKMADVDGNGHIDREELRNLLESMES 60 >1FW4-A nrPDB Length = 71 Score = 70.8 bits (172), Expect = 4e-13, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 37/80 (46%), Gaps = 12/80 (15%) Query: 94 RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIF 153 + +++ AF+++D D NG IS E+ ++ + E ++ V+++ Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG------------EKLTDEEVDEMI 48 Query: 154 NMMDKNKDGQLTLEEFCEGS 173 D + DGQ+ EEF + Sbjct: 49 READIDGDGQVNYEEFVQMM 68 Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 33/69 (47%) Query: 59 GDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISY 118 D F VFD D NGYI E ++ ++++ + D+D +G ++Y Sbjct: 2 TDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNY 61 Query: 119 DEMLRIVDA 127 +E ++++ A Sbjct: 62 EEFVQMMTA 70 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+++ ++ F KD +G+++ +E + + + + D D +G +++ Sbjct: 4 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNL-GEKLTDEEVDEMIREADIDGDGQVNY 61 Query: 83 KEFICALSVT 92 +EF+ ++ Sbjct: 62 EEFVQMMTAK 71 >2KN2-A nrPDB Length = 92 Score = 70.4 bits (171), Expect = 5e-13, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 36/82 (43%), Gaps = 12/82 (14%) Query: 92 TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNK 151 + ++L AF+++D D NG IS E+ ++ + E ++ V + Sbjct: 2 HMDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLG------------EKLTDEEVEQ 49 Query: 152 IFNMMDKNKDGQLTLEEFCEGS 173 + D + DGQ+ EEF + Sbjct: 50 MIKEADLDGDGQVNYEEFVKMM 71 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 34/71 (47%) Query: 59 GDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISY 118 D + F VFD D+NGYI E + ++++ + DLD +G ++Y Sbjct: 5 TDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNY 64 Query: 119 DEMLRIVDAIY 129 +E ++++ + Sbjct: 65 EEFVKMMMTVR 75 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 ++EL++ +K F KD +G+++ SE + + E + D D +G ++++ Sbjct: 8 EEELKEAFKVFDKD-QNGYISASELRHVMINL-GEKLTDEEVEQMIKEADLDGDGQVNYE 65 Query: 84 EFICALS 90 EF+ + Sbjct: 66 EFVKMMM 72 >2LC5-A nrPDB Length = 151 Score = 70.4 bits (171), Expect = 5e-13, Method: Composition-based stats. Identities = 26/161 (16%), Positives = 67/161 (41%), Gaps = 16/161 (9%) Query: 14 QDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFD 73 + T +++E ++ ++ F KD + L E + + +E + +D Sbjct: 3 EQKKVLTAEEQQEYKEAFQLFDKDNDN-KLTAEELGTVMRALGANPTKQKISE-IVKDYD 60 Query: 74 ADKNGYIDFKEFICALSVTSRG-ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D +G D + F+ + + + + + AF+++D + NG IS E+ ++ + Sbjct: 61 KDNSGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTTLG--- 117 Query: 133 GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E E+ V+ + + ++G + +++F + Sbjct: 118 ---------EKLTEQEVDDLLKEIGV-EEGLINVDDFVKLI 148 Score = 46.2 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 49/105 (46%), Gaps = 2/105 (1%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 K+++ + K + KD SG ++ F I ++ D + + F +FD +KNGYI Sbjct: 48 TKQKISEIVKDYDKDN-SGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISA 106 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 E L+ ++ + ++ GLI+ D+ ++++ + Sbjct: 107 SELKHVLTTLGEKLTEQEVDDLLKEIGVEE-GLINVDDFVKLITS 150 >3IFK-A nrPDB Length = 90 Score = 68.9 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 39/90 (43%), Gaps = 3/90 (3%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD N Sbjct: 3 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 60 Query: 78 GYIDFKEFICALSVTSR-GELNDKLIWAFQ 106 G IDF EF+ ++ + + +++ AF+ Sbjct: 61 GTIDFPEFLTMMARKMKDTDSEEEIREAFR 90 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 58 Query: 160 KDGQLTLEEFCEGSKR 175 +G + EF R Sbjct: 59 GNGTIDFPEFLTMMAR 74 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 32/78 (41%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 A + F++FD D +G I KE + + +L D D NG I + E L Sbjct: 10 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 69 Query: 123 RIVDAIYKMVGSMVKLPE 140 ++ K S ++ E Sbjct: 70 TMMARKMKDTDSEEEIRE 87 >2KZ2-A nrPDB Length = 94 Score = 68.5 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 38/84 (45%), Gaps = 12/84 (14%) Query: 90 SVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRV 149 S+ + +++ AF++ D D NG IS E+ ++ + E ++ V Sbjct: 20 SLMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLG------------EKLTDEEV 67 Query: 150 NKIFNMMDKNKDGQLTLEEFCEGS 173 +++ D + DGQ+ EEF + Sbjct: 68 DEMIREADIDGDGQVNYEEFVQMM 91 Score = 50.4 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 34/76 (44%) Query: 52 YKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLD 111 ++ D F V D D NGYI E ++ ++++ + D+D Sbjct: 18 FQSLMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADID 77 Query: 112 NNGLISYDEMLRIVDA 127 +G ++Y+E ++++ A Sbjct: 78 GDGQVNYEEFVQMMTA 93 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 10/70 (14%), Positives = 34/70 (48%), Gaps = 2/70 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+++ ++ KD +G+++ +E + + + + D D +G +++ Sbjct: 27 SEEEIREAFRVEDKD-GNGYISAAELRHVMTNL-GEKLTDEEVDEMIREADIDGDGQVNY 84 Query: 83 KEFICALSVT 92 +EF+ ++ Sbjct: 85 EEFVQMMTAK 94 >2N7L-C nrPDB Length = 141 Score = 67.0 bits (162), Expect = 4e-12, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 33/84 (39%), Gaps = 1/84 (1%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDAD 75 + + T K E + + F G ++ E K+ + P E + + D D Sbjct: 24 VEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQE-MIDEVDED 82 Query: 76 KNGYIDFKEFICALSVTSRGELND 99 +G +DF EF+ + + + + Sbjct: 83 GSGTVDFDEFLVMMVRXMKDDSEN 106 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 24/61 (39%) Query: 77 NGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 +G I KE + + + ++L D D +G + +DE L ++ K + Sbjct: 48 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRXMKDDSENL 107 Query: 137 K 137 Sbjct: 108 Y 108 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 12/79 (15%), Positives = 34/79 (43%), Gaps = 13/79 (16%) Query: 98 NDKLIWAFQLYDLDN-NGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMM 156 ++ AF ++ L +G IS E+ +++ + + + + + ++ + + Sbjct: 32 KNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQ------------NPTPEELQEMIDEV 79 Query: 157 DKNKDGQLTLEEFCEGSKR 175 D++ G + +EF R Sbjct: 80 DEDGSGTVDFDEFLVMMVR 98 >2AMI-A nrPDB Length = 96 Score = 67.0 bits (162), Expect = 5e-12, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%) Query: 9 SQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYV 68 +DQ + V T K+E+++ + F D SG ++ E + + F + + Sbjct: 14 RRDQKKGRVGLTEEQKQEIREAFDLFDTD-GSGTIDAKELKVAMRAL-GFEPKKEEIKKM 71 Query: 69 FNVFDADKNGYIDFKEFICALSVTS 93 + D D +G IDF+EF+ ++ Sbjct: 72 ISEIDKDGSGTIDFEEFLTMMTAKM 96 Score = 58.1 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 30/68 (44%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 + F++FD D +G ID KE A+ +++ D D +G I ++ Sbjct: 27 EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFE 86 Query: 120 EMLRIVDA 127 E L ++ A Sbjct: 87 EFLTMMTA 94 Score = 54.6 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 31/76 (40%), Gaps = 12/76 (15%) Query: 98 NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMD 157 ++ AF L+D D +G I E+ + A+ ++ + K+ + +D Sbjct: 29 KQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPK------------KEEIKKMISEID 76 Query: 158 KNKDGQLTLEEFCEGS 173 K+ G + EEF Sbjct: 77 KDGSGTIDFEEFLTMM 92 >2RO9-A nrPDB Length = 69 Score = 67.0 bits (162), Expect = 5e-12, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 12/80 (15%) Query: 96 ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM 155 + ++L AF+++D D NG IS E+ ++ + E ++ V+++ Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLG------------EKLTDEEVDEMIRE 48 Query: 156 MDKNKDGQLTLEEFCEGSKR 175 D + DGQ+ EEF + Sbjct: 49 ADVDGDGQINYEEFVKVMMA 68 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 35/68 (51%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 D + F VFD D+NG+I E ++ ++++ + D+D +G I+Y+ Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 120 EMLRIVDA 127 E ++++ A Sbjct: 61 EFVKVMMA 68 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++EL++ ++ F KD +G ++ +E + + + + D D +G I++ Sbjct: 2 SEEELKEAFRVFDKD-QNGFISAAELRHVMTNL-GEKLTDEEVDEMIREADVDGDGQINY 59 Query: 83 KEFICALSVT 92 +EF+ + Sbjct: 60 EEFVKVMMAK 69 >5COC-A nrPDB Length = 130 Score = 66.6 bits (161), Expect = 6e-12, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 33/82 (40%), Gaps = 2/82 (2%) Query: 13 LQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVF 72 L D + E ++ + F KD G + E + + A + + N Sbjct: 51 LNDAQAAAEECIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEV 108 Query: 73 DADKNGYIDFKEFICALSVTSR 94 DAD NG IDF EF+ ++ + Sbjct: 109 DADGNGTIDFPEFLTMMARKMK 130 Score = 53.9 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 64 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 111 Query: 160 KDGQLTLEEFCEGSKR 175 +G + EF R Sbjct: 112 GNGTIDFPEFLTMMAR 127 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 24/102 (23%), Positives = 41/102 (40%), Gaps = 1/102 (0%) Query: 25 KELQQWYKGFFKDCPSGHLNK-SEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 +E + + KD PS N +E + + + A + F++FD D +G I K Sbjct: 24 EEQRNAFIQSLKDDPSQSANLLAEAKCLNDAQAAAEECIAEFKEAFSLFDKDGDGTITTK 83 Query: 84 EFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 E + + +L D D NG I + E L ++ Sbjct: 84 ELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 125 >5VLN-A nrPDB Length = 120 Score = 66.6 bits (161), Expect = 6e-12, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 34/88 (38%), Gaps = 1/88 (1%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDAD 75 + + T K E + + F G ++ E K+ + P E + + D D Sbjct: 9 VEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQE-MIDEVDED 67 Query: 76 KNGYIDFKEFICALSVTSRGELNDKLIW 103 +G +DF EF+ + + + + K Sbjct: 68 GSGTVDFDEFLVMMVRSMKDDSKGKFKR 95 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 22/49 (44%) Query: 77 NGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 +G I KE + + + ++L D D +G + +DE L ++ Sbjct: 33 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMM 81 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 34/80 (42%), Gaps = 13/80 (16%) Query: 98 NDKLIWAFQLYDLDN-NGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMM 156 ++ AF ++ L +G IS E+ +++ + + + + + ++ + + Sbjct: 17 KNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQ------------NPTPEELQEMIDEV 64 Query: 157 DKNKDGQLTLEEFCEGSKRD 176 D++ G + +EF R Sbjct: 65 DEDGSGTVDFDEFLVMMVRS 84 >2M5E-A nrPDB Length = 73 Score = 65.4 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 12/81 (14%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 + ++LI AF+++D D NGLIS E+ ++ + E + V+++ Sbjct: 2 KEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLG------------EKLTDDEVDEM 49 Query: 153 FNMMDKNKDGQLTLEEFCEGS 173 D + DG + EEF Sbjct: 50 IREADIDGDGHINYEEFVRMM 70 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 32/72 (44%) Query: 56 FPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGL 115 D F VFD D NG I E ++ +D++ + D+D +G Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGH 60 Query: 116 ISYDEMLRIVDA 127 I+Y+E +R++ + Sbjct: 61 INYEEFVRMMVS 72 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++EL + +K F +D +G ++ +E + + + + D D +G+I++ Sbjct: 6 SEEELIEAFKVFDRD-GNGLISAAELRHVMTNL-GEKLTDDEVDEMIREADIDGDGHINY 63 Query: 83 KEFICAL 89 +EF+ + Sbjct: 64 EEFVRMM 70 >2ROB-A nrPDB Length = 70 Score = 64.3 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 36/78 (46%), Gaps = 12/78 (15%) Query: 96 ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM 155 + ++L AF+++D D NG IS E+ ++ + E ++ V ++ Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLG------------EKLTDEEVEQMIKE 48 Query: 156 MDKNKDGQLTLEEFCEGS 173 D + DGQ+ EEF + Sbjct: 49 ADLDGDGQVNYEEFVKMM 66 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 34/70 (48%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 D + F VFD D+NGYI E + ++++ + DLD +G ++Y+ Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 60 Query: 120 EMLRIVDAIY 129 E ++++ + Sbjct: 61 EFVKMMMTVR 70 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 ++EL++ +K F KD +G+++ SE + + E + D D +G ++++ Sbjct: 3 EEELKEAFKVFDKD-QNGYISASELRHVMINL-GEKLTDEEVEQMIKEADLDGDGQVNYE 60 Query: 84 EFICALS 90 EF+ + Sbjct: 61 EFVKMMM 67 >2LV7-A nrPDB Length = 100 Score = 64.3 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 12/72 (16%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 +++ AF+++D D NG IS E+ + ++ M E + I +D Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPN------------EVELEVIIQRLDM 83 Query: 159 NKDGQLTLEEFC 170 + DGQ+ EEF Sbjct: 84 DGDGQVDFEEFV 95 Score = 53.9 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 2/65 (3%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 +E+++ +K F +D +G ++K E + + E + D D +G +DF+E Sbjct: 36 EEIREAFKVFDRD-GNGFISKQELGTAMRSL-GYMPNEVELEVIIQRLDMDGDGQVDFEE 93 Query: 85 FICAL 89 F+ L Sbjct: 94 FVTLL 98 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 29/67 (43%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 D F VFD D NG+I +E A+ +L Q D+D +G + ++ Sbjct: 33 DELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFE 92 Query: 120 EMLRIVD 126 E + ++ Sbjct: 93 EFVTLLG 99 >2I08-A nrPDB Length = 78 Score = 63.9 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 33/79 (41%), Gaps = 2/79 (2%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDAD 75 + + T E ++ + + KD G + E + + A + + N DAD Sbjct: 1 MDQLTEEQIAEFKEAFSLYDKD-GDGTITTKELGTVMRSL-GLNPTEAELQDMINEVDAD 58 Query: 76 KNGYIDFKEFICALSVTSR 94 NG IDF EF+ ++ + Sbjct: 59 GNGTIDFPEFLTMMARIMK 77 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 31/76 (40%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF LYD D +G I+ E+ ++ ++ + E + + N +D + Sbjct: 11 EFKEAFSLYDKDGDGTITTKELGTVMRSLGL------------NPTEAELQDMINEVDAD 58 Query: 160 KDGQLTLEEFCEGSKR 175 +G + EF R Sbjct: 59 GNGTIDFPEFLTMMAR 74 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 28/68 (41%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 A + F+++D D +G I KE + +L D D NG I + E L Sbjct: 10 AEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFPEFL 69 Query: 123 RIVDAIYK 130 ++ I K Sbjct: 70 TMMARIMK 77 >4N5X-A nrPDB Length = 199 Score = 63.5 bits (153), Expect = 6e-11, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 57/144 (39%), Gaps = 20/144 (13%) Query: 35 FKDCPSGHLNKSEFQKIYKQFF-PFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTS 93 G ++ E Q+ + P G + E +F D +K+G +DF+EF+ L Sbjct: 31 LDRNGDGVVDIGELQEGLRNLGIPLGQDAE--EKIFTTGDVNKDGKLDFEEFMKYLKDH- 87 Query: 94 RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIF 153 K+ AF+ D +N+G I E+++ + + + E++ I Sbjct: 88 ----EKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTI------------SEQQAELIL 131 Query: 154 NMMDKNKDGQLTLEEFCEGSKRDP 177 +D + + E+ + +P Sbjct: 132 QSIDVDGTMTVDWNEWRDYFLFNP 155 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 41/109 (37%), Gaps = 17/109 (15%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 E +F D + +G +D E L D F D++ +G + ++E ++ + Sbjct: 25 ETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYL 84 Query: 126 DAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 EK++ F +DKN DG++ E + + Sbjct: 85 KDH-----------------EKKMKLAFKSLDKNNDGKIEASEIVQSLQ 116 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 39/100 (39%), Gaps = 12/100 (12%) Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDE 142 ++F+ + + E + FQ D + +G++ E+ + + +G + Sbjct: 6 RDFVLPTAASQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE----- 60 Query: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSA 182 KIF D NKDG+L EEF + K + Sbjct: 61 -------EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKL 93 Score = 29.6 bits (65), Expect = 0.78, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 30/80 (37%), Gaps = 2/80 (2%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 +K+++ +K K+ G + SE + Q AE + D D +D+ Sbjct: 88 EKKMKLAFKSLDKNN-DGKIEASEIVQSL-QTLGLTISEQQAELILQSIDVDGTMTVDWN 145 Query: 84 EFICALSVTSRGELNDKLIW 103 E+ ++ + + + Sbjct: 146 EWRDYFLFNPVTDIEEIIRF 165 >2HPS-A nrPDB Length = 186 Score = 63.1 bits (152), Expect = 7e-11, Method: Composition-based stats. Identities = 21/60 (35%), Positives = 29/60 (48%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 +++ D DK+GY+ EF L +DK I F D + NG IS DE L V+ Sbjct: 107 MYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFLVTVND 166 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 28/75 (37%), Gaps = 2/75 (2%) Query: 31 YKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALS 90 Y D G+++ EF+ + P FN D +KNG I EF+ ++ Sbjct: 108 YDCIDTD-KDGYVSLPEFKAFLQAVGPDLTDDKAIT-CFNTLDFNKNGQISRDEFLVTVN 165 Query: 91 VTSRGELNDKLIWAF 105 G L AF Sbjct: 166 DFLFGLEETALANAF 180 Score = 32.3 bits (72), Expect = 0.15, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 52/147 (35%), Gaps = 27/147 (18%) Query: 39 PSGHLNKSEFQKIYKQFFPFGDPSAFA-----EYVFNVFDADK---NGYIDFKEF-ICAL 89 G +++ +++ I + SA + V D I +E + A Sbjct: 27 GDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQLGLAPGVRISVEEAAVNAT 86 Query: 90 SVTSRGELNDKLIWAFQLY------DLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDED 143 + + +K + Q D D +G +S E + A+ D Sbjct: 87 DSLLKMKGEEKAMAVIQSLIMYDCIDTDKDGYVSLPEFKAFLQAVGP------------D 134 Query: 144 TPEKRVNKIFNMMDKNKDGQLTLEEFC 170 + + FN +D NK+GQ++ +EF Sbjct: 135 LTDDKAITCFNTLDFNKNGQISRDEFL 161 Score = 30.4 bits (67), Expect = 0.46, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 42/117 (35%), Gaps = 16/117 (13%) Query: 69 FNVFDADKNGYIDFK--EFICALSVTSRGELNDKLIWAFQLY--DLDNNGL-----ISYD 119 D +G+I + E I +K Q + D GL IS + Sbjct: 20 MQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQLGLAPGVRISVE 79 Query: 120 EML-RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E D++ KM G + + +++ +D +KDG ++L EF + Sbjct: 80 EAAVNATDSLLKMKGEEKAMAVIQSLI------MYDCIDTDKDGYVSLPEFKAFLQA 130 >4ZCV-A nrPDB Length = 165 Score = 63.1 bits (152), Expect = 7e-11, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 57/144 (39%), Gaps = 20/144 (13%) Query: 35 FKDCPSGHLNKSEFQKIYKQFF-PFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTS 93 G ++ E Q+ + P G + E +F D +K+G +DF+EF+ L Sbjct: 22 LDRNGDGVVDIGELQEGLRNLGIPLGQDAE--EKIFTTGDVNKDGKLDFEEFMKYLKDH- 78 Query: 94 RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIF 153 K+ AF+ D +N+G I E+++ + + + E++ I Sbjct: 79 ----EKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTI------------SEQQAELIL 122 Query: 154 NMMDKNKDGQLTLEEFCEGSKRDP 177 +D + + E+ + +P Sbjct: 123 QSIDVDGTMTVDWNEWRDYFLFNP 146 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 41/109 (37%), Gaps = 17/109 (15%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 E +F D + +G +D E L D F D++ +G + ++E ++ + Sbjct: 16 ETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYL 75 Query: 126 DAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 EK++ F +DKN DG++ E + + Sbjct: 76 KDH-----------------EKKMKLAFKSLDKNNDGKIEASEIVQSLQ 107 Score = 42.7 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 31/78 (39%), Gaps = 12/78 (15%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 FQ D + +G++ E+ + + +G + KIF D NKDG+L Sbjct: 19 FQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE------------EKIFTTGDVNKDGKL 66 Query: 165 TLEEFCEGSKRDPTIVSA 182 EEF + K + Sbjct: 67 DFEEFMKYLKDHEKKMKL 84 Score = 29.6 bits (65), Expect = 0.78, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 30/80 (37%), Gaps = 2/80 (2%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 +K+++ +K K+ G + SE + Q AE + D D +D+ Sbjct: 79 EKKMKLAFKSLDKNN-DGKIEASEIVQSL-QTLGLTISEQQAELILQSIDVDGTMTVDWN 136 Query: 84 EFICALSVTSRGELNDKLIW 103 E+ ++ + + + Sbjct: 137 EWRDYFLFNPVTDIEEIIRF 156 >5H7D-E nrPDB Length = 120 Score = 62.7 bits (151), Expect = 9e-11, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 + ++ + F KD G + E + + A + + N DAD NG IDF E Sbjct: 56 QAFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGNGTIDFPE 113 Query: 85 FICALSV 91 F+ ++ Sbjct: 114 FLTMMAR 120 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 31/74 (41%), Gaps = 12/74 (16%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 AF L+D D +G I+ E+ ++ ++ + + E + + N +D + + Sbjct: 59 KEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDADGN 106 Query: 162 GQLTLEEFCEGSKR 175 G + EF R Sbjct: 107 GTIDFPEFLTMMAR 120 Score = 53.9 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 30/75 (40%), Gaps = 1/75 (1%) Query: 51 IYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDL 110 + + AF E F++FD D +G I KE + + +L D Sbjct: 45 LLAEAKKLNQIQAFKE-AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDA 103 Query: 111 DNNGLISYDEMLRIV 125 D NG I + E L ++ Sbjct: 104 DGNGTIDFPEFLTMM 118 >2JNX-A nrPDB Length = 134 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 33/139 (23%), Positives = 52/139 (37%), Gaps = 20/139 (14%) Query: 35 FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSR 94 G ++ E + P + +F D D NG ID EF + Sbjct: 9 LDANGDGSVSYEEVKAFVSSKRPI-KNEQLLQLIFKAIDIDGNGEIDLAEFTKFAAAVKE 67 Query: 95 GELNDK---LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNK 151 +L+D+ L ++L D D +G ++ +E+ EK V++ Sbjct: 68 QDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGY---------------EKVVDQ 112 Query: 152 IFNMMDKNKDGQLTLEEFC 170 I D N DG +TLEEF Sbjct: 113 IMK-ADANGDGYITLEEFL 130 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 32/74 (43%), Gaps = 12/74 (16%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 F+ D + +G +SY+E+ V + + E+ + IF +D + + Sbjct: 3 EALFKQLDANGDGSVSYEEVKAFVSSKRPIKN------------EQLLQLIFKAIDIDGN 50 Query: 162 GQLTLEEFCEGSKR 175 G++ L EF + + Sbjct: 51 GEIDLAEFTKFAAA 64 Score = 32.3 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 6/61 (9%) Query: 27 LQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFI 86 L+ YK D G L K E +K+F + + DA+ +GYI +EF+ Sbjct: 77 LKILYKLMDAD-GDGKLTKEEVTTFFKKFG----YEKVVDQIMKA-DANGDGYITLEEFL 130 Query: 87 C 87 Sbjct: 131 A 131 >2RO8-A nrPDB Length = 79 Score = 61.6 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 2/79 (2%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + T E ++ + F KD G + E + + A + + N DAD N Sbjct: 3 QLTDEQISEFKEAFSLFDKD-GDGCITTKELGTVMRSLGQNP-TEAELQDMINEVDADGN 60 Query: 78 GYIDFKEFICALSVTSRGE 96 G IDF EF+ ++ + Sbjct: 61 GTIDFPEFLNLMARKMKDT 79 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 58 Query: 160 KDGQLTLEEFCEGSKR 175 +G + EF R Sbjct: 59 GNGTIDFPEFLNLMAR 74 Score = 46.2 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 27/63 (42%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 + + F++FD D +G I KE + + +L D D NG I + E L Sbjct: 10 SEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 69 Query: 123 RIV 125 ++ Sbjct: 70 NLM 72 >4GJF-A nrPDB Length = 89 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 33/82 (40%), Gaps = 1/82 (1%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDAD 75 + + T K E + + F + G ++ E K+ + P E + + D D Sbjct: 9 VEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQE-MIDEVDED 67 Query: 76 KNGYIDFKEFICALSVTSRGEL 97 +G +DF EF+ + + + Sbjct: 68 GSGTVDFDEFLVMMVRCMKDDS 89 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 22/49 (44%) Query: 77 NGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 +G I KE + + + ++L D D +G + +DE L ++ Sbjct: 33 DGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMM 81 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 11/79 (13%), Positives = 33/79 (41%), Gaps = 13/79 (16%) Query: 98 NDKLIWAFQLYDLDN-NGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMM 156 ++ AF ++ +G IS E+ +++ + + + + + ++ + + Sbjct: 17 KNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQ------------NPTPEELQEMIDEV 64 Query: 157 DKNKDGQLTLEEFCEGSKR 175 D++ G + +EF R Sbjct: 65 DEDGSGTVDFDEFLVMMVR 83 >3AAJ-A nrPDB Length = 167 Score = 60.4 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 26/157 (16%), Positives = 57/157 (36%), Gaps = 21/157 (13%) Query: 31 YKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALS 90 ++ KD SG ++ +E Q+ + ++FD + ++F EF Sbjct: 10 FQRVDKD-RSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWK 68 Query: 91 VTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVN 150 + + F+ YD DN+G+I +E+ + + ++ + Sbjct: 69 YITDWQ------NVFRTYDRDNSGMIDKNELKQALSGYR--------------LSDQFHD 108 Query: 151 KIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYD 187 + D+ GQ+ ++F +G + YD Sbjct: 109 ILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYD 145 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 12/103 (11%) Query: 28 QQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFIC 87 Q ++ + +D SG ++K+E ++ + F + + FD G I F +FI Sbjct: 74 QNVFRTYDRDN-SGMIDKNELKQALSGYRL---SDQFHDILIRKFDRQGRGQIAFDDFIQ 129 Query: 88 ALSVTSRGELNDKLIWAFQLYDLDNNGLI--SYDEMLRIVDAI 128 V +L F+ YD D +G I SY++ L +V +I Sbjct: 130 GCIVL------QRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 166 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 35/157 (22%), Positives = 66/157 (42%), Gaps = 32/157 (20%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 T F+ ++ F ++ +G +N SEF ++K + + VF +D D +G Sbjct: 36 TPFNPVTVRSIISMFDRENKAG-VNFSEFTGVWKYITDW-------QNVFRTYDRDNSGM 87 Query: 80 IDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKL 138 ID E ALS + +D LI + +D G I++D+ ++ + Sbjct: 88 IDKNELKQALSGYRLSDQFHDILI---RKFDRQGRGQIAFDDFIQGCIVL---------- 134 Query: 139 PEDEDTPEKRVNKIFNMMDKNKDG--QLTLEEFCEGS 173 +R+ IF D ++DG Q++ E++ Sbjct: 135 --------QRLTDIFRRYDTDQDGWIQVSYEQYLSMV 163 >2B1U-A nrPDB Length = 71 Score = 59.6 bits (143), Expect = 7e-10, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 38/78 (48%), Gaps = 12/78 (15%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 + L AF+ +D D +G I+ DE+ R + + + + P++ ++ + D Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPL------------PQEELDAMIREADV 53 Query: 159 NKDGQLTLEEFCEGSKRD 176 ++DG++ EEF ++ Sbjct: 54 DQDGRVNYEEFARMLAQE 71 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 31/60 (51%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 + F FD D +G+I E A++ + ++L + D+D +G ++Y+E R++ Sbjct: 9 QVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARML 68 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 31/66 (46%), Gaps = 2/66 (3%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 ++LQ ++ F +D GH+ E ++ P + + D D++G ++++E Sbjct: 6 EDLQVAFRAFDQD-GDGHITVDELRRAMAGL-GQPLPQEELDAMIREADVDQDGRVNYEE 63 Query: 85 FICALS 90 F L+ Sbjct: 64 FARMLA 69 >5OTJ-D nrPDB Length = 110 Score = 59.3 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 31/83 (37%), Gaps = 13/83 (15%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 D + F+ +D + +G IS E+ + + T V ++ +D Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLG-------------STSADEVQRMMAEIDT 49 Query: 159 NKDGQLTLEEFCEGSKRDPTIVS 181 + DG + EF +P ++ Sbjct: 50 DGDGFIDFNEFISFCNANPGLMK 72 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 ++++ +K F + G ++ SE + + + + D D +G+IDF E Sbjct: 3 DDMERIFKRFDTN-GDGKISLSELTDALRTLG--STSADEVQRMMAEIDTDGDGFIDFNE 59 Query: 85 FICALSVTS 93 FI + Sbjct: 60 FISFCNANP 68 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 33/78 (42%), Gaps = 1/78 (1%) Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 E +F FD + +G I E AL D++ D D +G I ++E + Sbjct: 5 MERIFKRFDTNGDGKISLSELTDALRTLGS-TSADEVQRMMAEIDTDGDGFIDFNEFISF 63 Query: 125 VDAIYKMVGSMVKLPEDE 142 +A ++ + K+ + E Sbjct: 64 CNANPGLMKDVAKVFKGE 81 >4Q57-A nrPDB Length = 65 Score = 59.3 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEF 85 E ++ + F KD G + E + + A + + N DAD NG IDF EF Sbjct: 3 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGNGTIDFPEF 60 Query: 86 ICALS 90 + ++ Sbjct: 61 LTMMA 65 Score = 50.4 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 31/74 (41%), Gaps = 12/74 (16%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D D +G I+ E+ ++ ++ + + E + + N +D + Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 50 Query: 160 KDGQLTLEEFCEGS 173 +G + EF Sbjct: 51 GNGTIDFPEFLTMM 64 Score = 50.4 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 27/63 (42%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 A + F++FD D +G I KE + + +L D D NG I + E L Sbjct: 2 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 61 Query: 123 RIV 125 ++ Sbjct: 62 TMM 64 >2BL0-B nrPDB Length = 145 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 23/152 (15%), Positives = 52/152 (34%), Gaps = 19/152 (12%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++Q+ ++ F KD G ++ E + +A + +A D Sbjct: 3 SADQIQECFQIFDKDN-DGKVSIEELGSALRSLGKNP-TNAELNTIKGQLNAK---EFDL 57 Query: 83 KEFICALSVTSRGELND--KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPE 140 F + +++ AF+ D + NG I E+ +++ + + S Sbjct: 58 ATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSS----- 112 Query: 141 DEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEG 172 V ++ + + DG + E F + Sbjct: 113 -------EVEELMKEVSVSGDGAINYESFVDM 137 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 41/100 (41%), Gaps = 10/100 (10%) Query: 41 GHLNKSEF-----QKIYKQFFPFGDPSAFAEYVFNVF---DADKNGYIDFKEFICALSVT 92 G LN EF + +Y++ P P+ ++ + + F D + NG I E L Sbjct: 48 GQLNAKEFDLATFKTVYRK--PIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNL 105 Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 + ++ + + +G I+Y+ + ++ Y + Sbjct: 106 GDALTSSEVEELMKEVSVSGDGAINYESFVDMLVTGYPLA 145 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 33/103 (32%), Gaps = 23/103 (22%) Query: 95 GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVN---- 150 D++ FQ++D DN+G +S +E+ + ++ K + K + Sbjct: 1 TASADQIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTIKGQLNAKEFDLATF 60 Query: 151 -------------------KIFNMMDKNKDGQLTLEEFCEGSK 174 F +DK +G + E + Sbjct: 61 KTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLL 103 >1F55-A nrPDB Length = 77 Score = 58.1 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 31/76 (40%), Gaps = 2/76 (2%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 T E ++ + F KD +G ++ SE + + A + N D D N Sbjct: 4 LTEEQIAEFKEAFALFDKDN-NGSISSSELATVMRSL-GLSPSEAEVNDLMNEIDVDGNH 61 Query: 79 YIDFKEFICALSVTSR 94 I+F EF+ +S + Sbjct: 62 QIEFSEFLALMSRQLK 77 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF L+D DNNG IS E+ ++ ++ E VN + N +D + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGL------------SPSEAEVNDLMNEIDVD 58 Query: 160 KDGQLTLEEFCEGSKR 175 + Q+ EF R Sbjct: 59 GNHQIEFSEFLALMSR 74 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 24/63 (38%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 A + F +FD D NG I E + ++ D+D N I + E L Sbjct: 10 AEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFL 69 Query: 123 RIV 125 ++ Sbjct: 70 ALM 72 >2Q4U-A nrPDB Length = 272 Score = 57.7 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 27/185 (14%), Positives = 65/185 (35%), Gaps = 25/185 (13%) Query: 21 RFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSA---------FAEYVFNV 71 D Q ++ F D +G++ E ++ P + + Sbjct: 7 NLDAAGFLQIWQHFDAD-DNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSA 65 Query: 72 FDADKNGYIDFKE-----------FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 +DA +G + +E F+ + + + + + ++ YD D++G IS E Sbjct: 66 YDATFDGRLQIEELANMILPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAE 125 Query: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 + + ++ + + ++ + + + DKNKDG+L L + + Sbjct: 126 LKNFLKDLFLQHKKKIPP----NKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFL 181 Query: 181 SALSL 185 + Sbjct: 182 LQFKM 186 Score = 46.2 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 32/163 (19%), Positives = 61/163 (37%), Gaps = 24/163 (14%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFF-------PFGDPSAFAEYVFNVFDADKNG 78 E + ++ + D SG+++ +E + K F P + + + +FD +K+G Sbjct: 105 EFMKIWRKYDAD-SSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDG 163 Query: 79 YIDFKEFICALSVT------------SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVD 126 +D + L++ S+ E F YD+ G + E VD Sbjct: 164 RLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPE----VD 219 Query: 127 AIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 K + +V+ +K + D NKDG++ E Sbjct: 220 GFVKDMMELVRPSISGGDLDKFRECLLTHCDMNKDGKIQKSEL 262 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 34/185 (18%), Positives = 67/185 (36%), Gaps = 23/185 (12%) Query: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCP---SGHLNKSE----------- 47 GK + L+ L + + +QQ K F G L E Sbjct: 30 GKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFDGRLQIEELANMILPQEEN 89 Query: 48 FQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE--------FICALSVTSRGELND 99 F I+++ P + F ++ +DAD +GYI E F+ +L++ Sbjct: 90 FLLIFRREAPLDNSVEFM-KIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDE 148 Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 +++D + +G + +++ RI+ + + ++ KIF D + Sbjct: 149 YTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVS 208 Query: 160 KDGQL 164 + G L Sbjct: 209 RTGAL 213 Score = 30.4 bits (67), Expect = 0.51, Method: Composition-based stats. Identities = 21/117 (17%), Positives = 40/117 (34%), Gaps = 19/117 (16%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFG-----DPSAFAEY------VFNVFD 73 E F G L+ ++ +I F D S+ E +F +D Sbjct: 147 DEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYD 206 Query: 74 ADKNGYIDFKE---FICALSVTSRGELN----DKLIWAFQLY-DLDNNGLISYDEML 122 + G ++ E F+ + R ++ DK + D++ +G I E+ Sbjct: 207 VSRTGALEGPEVDGFVKDMMELVRPSISGGDLDKFRECLLTHCDMNKDGKIQKSELA 263 >1JFJ-A nrPDB Length = 134 Score = 57.3 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 33/140 (23%), Positives = 54/140 (38%), Gaps = 20/140 (14%) Query: 38 CPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL-SVTSRGE 96 G ++ E + + + +F DAD NG ID EF S+ + Sbjct: 12 NGDGAVSYEEVKAFVSKKRAI-KNEQLLQLIFKSIDADGNGEIDQNEFAKFYGSIQGQDL 70 Query: 97 LNDK--LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFN 154 +DK L ++L D+D +G ++ +E+ ++V + Sbjct: 71 SDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHGI----------------EKVAEQVM 114 Query: 155 MMDKNKDGQLTLEEFCEGSK 174 D N DG +TLEEF E S Sbjct: 115 KADANGDGYITLEEFLEFSL 134 Score = 27.7 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 13/30 (43%) Query: 150 NKIFNMMDKNKDGQLTLEEFCEGSKRDPTI 179 +F +D N DG ++ EE + I Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAI 32 >2K7C-A nrPDB Length = 72 Score = 57.0 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 11/77 (14%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 +L AF+ +D + +G IS E+ + + + + +I +D Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGH-----------QVGHRDIEEIIRDVDL 55 Query: 159 NKDGQLTLEEFCEGSKR 175 N DG++ EEF R Sbjct: 56 NGDGRVDFEEFVRMMSR 72 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 KEL+ ++ F + G ++ SE ++ ++ E + D + +G +DF+E Sbjct: 7 KELRDAFREFDTN-GDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEE 65 Query: 85 FICALSV 91 F+ +S Sbjct: 66 FVRMMSR 72 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 27/64 (42%), Gaps = 1/64 (1%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALS-VTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 F FD + +G I E A+ + + + + DL+ +G + ++E Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEF 66 Query: 122 LRIV 125 +R++ Sbjct: 67 VRMM 70 >1JC2-A nrPDB Length = 76 Score = 56.6 bits (135), Expect = 6e-09, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 37/80 (46%), Gaps = 12/80 (15%) Query: 94 RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIF 153 +G+ ++L F+++D + +G I +E+ I+ A E E+ + + Sbjct: 5 KGKSEEELANCFRIFDKNADGFIDIEELGEILRATG------------EHVIEEDIEDLM 52 Query: 154 NMMDKNKDGQLTLEEFCEGS 173 DKN DG++ +EF + Sbjct: 53 KDSDKNNDGRIDFDEFLKMM 72 Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 34/70 (48%) Query: 59 GDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISY 118 G F +FD + +G+ID +E L T + + + + D +N+G I + Sbjct: 6 GKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDF 65 Query: 119 DEMLRIVDAI 128 DE L++++ + Sbjct: 66 DEFLKMMEGV 75 Score = 26.9 bits (58), Expect = 5.3, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 19/38 (50%) Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + + + E+ + F + DKN DG + +EE E + Sbjct: 1 MEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRA 38 >1OZS-A nrPDB Length = 73 Score = 56.6 bits (135), Expect = 7e-09, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 38/82 (46%), Gaps = 12/82 (14%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 +G+ ++L F+++D + +G I +E+ ++ A E E + ++ Sbjct: 1 MKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATG------------ETITEDDIEEL 48 Query: 153 FNMMDKNKDGQLTLEEFCEGSK 174 DKN DG++ +EF E K Sbjct: 49 MKDGDKNNDGRIDYDEFLEFMK 70 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 31/70 (44%) Query: 59 GDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISY 118 G +F +FD + +GYID +E L T D + + D +N+G I Y Sbjct: 3 GKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDY 62 Query: 119 DEMLRIVDAI 128 DE L + + Sbjct: 63 DEFLEFMKGV 72 Score = 35.4 bits (80), Expect = 0.017, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 2/68 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++EL ++ F K+ G+++ E KI Q E + D + +G ID+ Sbjct: 5 SEEELSDLFRMFDKNA-DGYIDLEEL-KIMLQATGETITEDDIEELMKDGDKNNDGRIDY 62 Query: 83 KEFICALS 90 EF+ + Sbjct: 63 DEFLEFMK 70 Score = 27.3 bits (59), Expect = 3.9, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 18/34 (52%) Query: 142 EDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + E+ ++ +F M DKN DG + LEE + Sbjct: 2 KGKSEEELSDLFRMFDKNADGYIDLEELKIMLQA 35 >2LVK-A nrPDB Length = 77 Score = 56.2 bits (134), Expect = 8e-09, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 31/83 (37%), Gaps = 13/83 (15%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 D + F+ +D + +G IS E+ + + T V ++ +D Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLG-------------STSADEVQRMMAEIDT 48 Query: 159 NKDGQLTLEEFCEGSKRDPTIVS 181 + DG + EF +P ++ Sbjct: 49 DGDGFIDFNEFISFCNANPGLMK 71 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 ++++ +K F + G ++ SE + + + + D D +G+IDF E Sbjct: 2 DDMERIFKRFDTN-GDGKISLSELTDALRTLG--STSADEVQRMMAEIDTDGDGFIDFNE 58 Query: 85 FICALSVTS 93 FI + Sbjct: 59 FISFCNANP 67 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 30/73 (41%), Gaps = 1/73 (1%) Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 E +F FD + +G I E AL D++ D D +G I ++E + Sbjct: 4 MERIFKRFDTNGDGKISLSELTDALRTLGS-TSADEVQRMMAEIDTDGDGFIDFNEFISF 62 Query: 125 VDAIYKMVGSMVK 137 +A ++ + K Sbjct: 63 CNANPGLMKDVAK 75 >1M39-A nrPDB Length = 89 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 48/96 (50%), Gaps = 13/96 (13%) Query: 81 DFKEFICALSVTSRG-ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLP 139 +F +F+ ++ + ++++ AF+L+D D G IS+ + R+ + Sbjct: 2 NFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELG---------- 51 Query: 140 EDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E+ ++ + ++ + D++ DG+++ +EF K+ Sbjct: 52 --ENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKK 85 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 30/82 (36%) Query: 47 EFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQ 106 +F + Q D F +FD D+ G I FK +++L Sbjct: 5 DFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMID 64 Query: 107 LYDLDNNGLISYDEMLRIVDAI 128 D D +G +S E LRI+ Sbjct: 65 EADRDGDGEVSEQEFLRIMKKT 86 Score = 36.9 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 K+E+ + +K F D +G ++ +++ K+ E + + D D +G + Sbjct: 19 TKEEILKAFKLFDDD-ETGKISFKNLKRVAKELGENLTDEELQE-MIDEADRDGDGEVSE 76 Query: 83 KEFICALSVTS 93 +EF+ + TS Sbjct: 77 QEFLRIMKKTS 87 >5TBY-E nrPDB Length = 166 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 20/157 (12%), Positives = 62/157 (39%), Gaps = 19/157 (12%) Query: 20 TRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 + F++ ++Q++ + F G ++K++ + + + + + + Sbjct: 19 SMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMI----KEAP 74 Query: 78 GYIDFKEFICALSVTSRGELNDK-LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 G I+F F+ +G ++ ++ AF+++D + G++ D + ++ Sbjct: 75 GPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLT---------- 124 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 + E ++ V+++F + G L + Sbjct: 125 --TQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHII 159 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 13/96 (13%), Positives = 37/96 (38%), Gaps = 22/96 (22%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 + AF + D + +G I +++ A+ ++ + + ++++ Sbjct: 27 QEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRV-----------NVKNEEIDEMIKEA-- 73 Query: 159 NKDGQLTLEEF-------CEGSKRDPTIVSALSLYD 187 G + F +G+ + TI++A ++D Sbjct: 74 --PGPINFTVFLTMFGEKLKGADPEETILNAFKVFD 107 Score = 33.8 bits (76), Expect = 0.043, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 33/86 (38%) Query: 41 GHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDK 100 G +N + F ++ + DP F VFD + G + L+ + ++ Sbjct: 75 GPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEE 134 Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVD 126 + F + D G + Y ++ I+ Sbjct: 135 VDQMFAAFPPDVTGNLDYKNLVHIIT 160 >1TNP-A nrPDB Length = 90 Score = 54.6 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 37/83 (44%) Query: 49 QKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLY 108 Q+ + F + A + F++FDAD G I KE + + + ++L + Sbjct: 6 QQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEV 65 Query: 109 DLDNNGLISYDEMLRIVDAIYKM 131 D D +G I ++E L ++ K Sbjct: 66 DEDGSGTIDFEEFLVMMVRQMKE 88 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 33/91 (36%), Gaps = 2/91 (2%) Query: 6 SKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFA 65 + ++ Q + + E + + F D G ++ E + + Sbjct: 1 ASMTDQQAEARAFLSEEMIAEFKAAFDMFDADGG-GDISTKELGTVMRMLGQNP-TKEEL 58 Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGE 96 + + D D +G IDF+EF+ + + + Sbjct: 59 DAIIEEVDEDGSGTIDFEEFLVMMVRQMKED 89 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF ++D D G IS E+ ++ + + + ++ ++ I +D++ Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMRMLGQ------------NPTKEELDAIIEEVDED 68 Query: 160 KDGQLTLEEFCEGSKR 175 G + EEF R Sbjct: 69 GSGTIDFEEFLVMMVR 84 >1C7W-A nrPDB Length = 81 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 41/88 (46%), Gaps = 11/88 (12%) Query: 94 RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIF 153 R + ++++ AF+++D + +G+I +DE I+ + +E + V + Sbjct: 3 RQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVG-----------EEPLTDAEVEEAM 51 Query: 154 NMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 D++ +G + + EF + K+ + Sbjct: 52 KEADEDGNGVIDIPEFMDLIKKSKNALK 79 Score = 46.9 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Query: 58 FGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND-KLIWAFQLYDLDNNGLI 116 D F VFDA+ +G IDF EF + L D ++ A + D D NG+I Sbjct: 3 RQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVI 62 Query: 117 SYDEMLRIVD 126 E + ++ Sbjct: 63 DIPEFMDLIK 72 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 32/76 (42%), Gaps = 1/76 (1%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 D++E+ + +K F + G ++ EF+ I ++ A E D D NG ID Sbjct: 6 DEEEILRAFKVFDAN-GDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDI 64 Query: 83 KEFICALSVTSRGELN 98 EF+ + + Sbjct: 65 PEFMDLIKKSKNALKE 80 >2M97-A nrPDB Length = 69 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 34/68 (50%) Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 F +FD D NG+ID +EF + +T ++ + F D D NG I +DE Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDE 60 Query: 121 MLRIVDAI 128 L++++ + Sbjct: 61 FLKMMENV 68 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 35/77 (45%), Gaps = 12/77 (15%) Query: 97 LNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMM 156 ++L F+++D D NG I +E I+ E ++ V++IF Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTG------------EQLTDEDVDEIFGDS 48 Query: 157 DKNKDGQLTLEEFCEGS 173 D +K+G++ +EF + Sbjct: 49 DTDKNGRIDFDEFLKMM 65 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++EL + ++ F KD +G +++ EF I + + +F D DKNG IDF Sbjct: 1 SEEELSECFRIFDKD-GNGFIDREEFGDIIR-LTGEQLTDEDVDEIFGDSDTDKNGRIDF 58 Query: 83 KEFICAL 89 EF+ + Sbjct: 59 DEFLKMM 65 >1W7I-B nrPDB Length = 151 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 22/155 (14%), Positives = 59/155 (38%), Gaps = 18/155 (11%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFN-VFDADKNGYIDFK 83 +E ++ ++ F + G + S+ + + + + + N D K+ +DF+ Sbjct: 10 EEFKEAFELFDR-VGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFE 68 Query: 84 EFICALSVTSRGE---LNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPE 140 F+ L ++ + + F+++D + NG + E+ ++ + Sbjct: 69 TFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLG----------- 117 Query: 141 DEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E E+ V + ++ +G + E F + Sbjct: 118 -EKMTEEEVETVLAGH-EDSNGCINYEAFLKHILS 150 >1Y1X-A nrPDB Length = 191 Score = 53.9 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 27/151 (17%), Positives = 54/151 (35%), Gaps = 20/151 (13%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 D +EL +W++ D SG ++ E A E + +++D + +G I F Sbjct: 25 DNQELMEWFRAVDTD-GSGAISVPELNAALSSA-GVPFSLATTEKLLHMYDKNHSGEITF 82 Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDE 142 EF + F+ D +G + +E+ + + V Sbjct: 83 DEFKDLHHFILS------MREGFRKRDSSGDGRLDSNEVRAALLSSGYQV---------- 126 Query: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 E+ + D+ + G L +++ E S Sbjct: 127 --SEQTFQALMRKFDRQRRGSLGFDDYVELS 155 >2G9B-A nrPDB Length = 263 Score = 53.5 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 49/127 (38%), Gaps = 16/127 (12%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFF-------PFGDPSAFAEYVFNVFDADKN 77 +E + ++ + D SG + E + K + + + + +FD++ + Sbjct: 103 EEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 161 Query: 78 GYIDFKEFICALSVTSRGELN--------DKLIWAFQLYDLDNNGLISYDEMLRIVDAIY 129 G ++ E L V L + AF+LYD D NG I +E+ ++ + Sbjct: 162 GKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 221 Query: 130 KMVGSMV 136 + + Sbjct: 222 EKNKQEL 228 Score = 53.1 bits (126), Expect = 7e-08, Method: Composition-based stats. Identities = 27/187 (14%), Positives = 63/187 (33%), Gaps = 19/187 (10%) Query: 12 QLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP-----SAFAE 66 + ++S+ + + + F D SG+L E Q + ++ S + Sbjct: 3 MAESHLQSSLITASQFFEIWLHFDAD-GSGYLEGKELQNLIQELLQARKKAGLELSPEMK 61 Query: 67 YVFNVFDADKNGYIDFKEFICALS---------VTSRGELNDKLIWAFQLYDLDNNGLIS 117 + + +G I E L + + ++ + ++ YD D++G I Sbjct: 62 TFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIE 121 Query: 118 YDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDP 177 +E+ + + + D+ + + + + D N DG+L L E Sbjct: 122 TEELKNFLKDLLEKANK----TVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQE 177 Query: 178 TIVSALS 184 + Sbjct: 178 NFLLKFQ 184 Score = 44.6 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 35/184 (19%), Positives = 72/184 (39%), Gaps = 21/184 (11%) Query: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYK------QF 55 GK L Q+ LQ ++ E++ + + + G + E + Sbjct: 35 GKELQNLIQELLQARKKAGLELSPEMKTFVDQYGQR-DDGKIGIVELAHVLPTEENFLLL 93 Query: 56 FPFGDPSAFAEYV--FNVFDADKNGYIDFKE---FICALSVTSRGELND-KLIWA----F 105 F + E++ + +D D +G+I+ +E F+ L + ++D KL Sbjct: 94 FRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLML 153 Query: 106 QLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLT 165 +L+D +N+G + EM R++ + + K NK F + D++ +G + Sbjct: 154 KLFDSNNDGKLELTEMARLLPVQENFLLKFQGIK----MCGKEFNKAFELYDQDGNGYID 209 Query: 166 LEEF 169 E Sbjct: 210 ENEL 213 >4D1E-A nrPDB Length = 876 Score = 53.5 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 47/110 (42%), Gaps = 4/110 (3%) Query: 15 DLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDA 74 D T+ E + + F + +G ++ +F+ + FA + + D Sbjct: 728 DAKGITQEQMNEFRASFNHFDRR-KNGLMDHEDFRACLISMGYDLGEAEFA-RIMTLVDP 785 Query: 75 DKNGYIDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 + G + F+ FI ++ T+ + +++I +F++ D I +E+ R Sbjct: 786 NGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKP-YILAEELRR 834 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 43/121 (35%), Gaps = 2/121 (1%) Query: 7 KLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAE 66 +L Q+ L + T + + ++ ++ +N+ E Q + + Sbjct: 682 QLIQEALVFDNKHTNYTMEHIRVGWELLLTTIAR-TINEVETQILTRDAKGITQEQMNEF 740 Query: 67 YV-FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 FN FD KNG +D ++F L + L D + G +++ + + Sbjct: 741 RASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTVTFQSFIDFM 800 Query: 126 D 126 Sbjct: 801 T 801 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 38/92 (41%), Gaps = 15/92 (16%) Query: 88 ALSVTSRGELND---KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDT 144 L+ ++G + + +F +D NGL+ +++ + ++ +G Sbjct: 724 ILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLG----------- 772 Query: 145 PEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRD 176 E +I ++D N G +T + F + R+ Sbjct: 773 -EAEFARIMTLVDPNGQGTVTFQSFIDFMTRE 803 >4P5W-A nrPDB Length = 411 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 35/171 (20%), Positives = 66/171 (38%), Gaps = 16/171 (9%) Query: 9 SQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSG--HLNKSEFQKIYKQFFPFGDPSAF-A 65 + + + + R D EL+ + + +G ++ ++F Y F P+ Sbjct: 21 TSEAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTV 80 Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKL-IWAFQLYDLDNNGLISYDEMLRI 124 E + V D K+G I F+EF+ SV D L + AFQL+D G ++++++ ++ Sbjct: 81 ELLSGVVDQTKDGLISFQEFVAFESVL---CAPDALFMVAFQLFDKAGKGEVTFEDVKQV 137 Query: 125 VDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + + + V F K LT EF + Sbjct: 138 FGQTT------IHQHIPFNWDSEFVQLHFGKERKRH---LTYAEFTQFLLE 179 >1TRF-A nrPDB Length = 76 Score = 53.1 bits (126), Expect = 7e-08, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 31/63 (49%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 A + F++FDAD G I KE + + + ++L + D D +G I ++E L Sbjct: 9 AEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFL 68 Query: 123 RIV 125 ++ Sbjct: 69 VMM 71 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 27/76 (35%), Gaps = 2/76 (2%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 + E + + F D G ++ E + + + + D D +G Sbjct: 3 LSEEMIAEFKAAFDMFDADGG-GDISTKELGTVMRMLGQNP-TKEELDAIIEEVDEDGSG 60 Query: 79 YIDFKEFICALSVTSR 94 IDF+EF+ + + Sbjct: 61 TIDFEEFLVMMVRQMK 76 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 12/76 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + AF ++D D G IS E+ ++ + + + ++ ++ I +D++ Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMRMLGQ------------NPTKEELDAIIEEVDED 57 Query: 160 KDGQLTLEEFCEGSKR 175 G + EEF R Sbjct: 58 GSGTIDFEEFLVMMVR 73 >1OQP-A nrPDB Length = 77 Score = 52.7 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 40/83 (48%), Gaps = 12/83 (14%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 + ++++ AF+L+D DN+G I+ ++ R+ + E+ E+ + ++ Sbjct: 3 GERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELG------------ENLTEEELQEM 50 Query: 153 FNMMDKNKDGQLTLEEFCEGSKR 175 D+N D ++ +EF K+ Sbjct: 51 IAEADRNDDNEIDEDEFIRIMKK 73 Score = 36.5 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 25/72 (34%) Query: 57 PFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLI 116 D F +FD D +G I K+ ++L D +++ I Sbjct: 3 GERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEI 62 Query: 117 SYDEMLRIVDAI 128 DE +RI+ Sbjct: 63 DEDEFIRIMKKT 74 Score = 33.8 bits (76), Expect = 0.039, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 31/71 (43%), Gaps = 2/71 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++E+ + ++ F D SG + + +++ K+ E + D + + ID Sbjct: 7 SREEILKAFRLFDDDN-SGTITIKDLRRVAKELGENLTEEELQE-MIAEADRNDDNEIDE 64 Query: 83 KEFICALSVTS 93 EFI + TS Sbjct: 65 DEFIRIMKKTS 75 >2N8Y-A nrPDB Length = 153 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 48/112 (42%), Gaps = 7/112 (6%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFF----PFGDPSAFAEYVFNVF 72 ++ E + + F +D SG L EF+ A + ++ Sbjct: 2 SSISQEQMNEFRASFNHFDRD-HSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIV 60 Query: 73 DADKNGYIDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 D ++ G + F+ FI +S T+ + D+++ +F++ D N I+ DE+ R Sbjct: 61 DPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITMDELRR 111 Score = 39.6 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 37/78 (47%), Gaps = 7/78 (8%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 ++ +F +D D++G + +E + ++ +G+ + + +I +++D Sbjct: 10 NEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFA-------RIMSIVDP 62 Query: 159 NKDGQLTLEEFCEGSKRD 176 N+ G +T + F + R+ Sbjct: 63 NRLGVVTFQAFIDFMSRE 80 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 41/116 (35%), Gaps = 19/116 (16%) Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELND-----KLIWAFQLYDLDNNGLISYDEMLR 123 FN FD D +G + +EF L ND + + D + G++++ + Sbjct: 16 FNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFID 75 Query: 124 IVDAIYKMVGSMVKLPEDEDTPEKRVNKI-FNMMDKNKDGQLTLEEFCEGSKRDPT 178 + + D DT ++ + DKN +T++E D Sbjct: 76 FM----------SRETADTDTADQVMASFKILAGDKN---YITMDELRRELPPDQA 118 >1YX7-A nrPDB Length = 83 Score = 51.9 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 35/77 (45%), Gaps = 6/77 (7%) Query: 96 ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM 155 ++ +L AF+ D + +G ++ E+ + + +D ++ K+ M Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTL------DAYKALSKDKVKEASAKLIKM 57 Query: 156 MDKNKDGQLTLEEFCEG 172 DKN DG+++ EEF Sbjct: 58 ADKNSDGKISKEEFLNA 74 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 29/68 (42%), Gaps = 6/68 (8%) Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTS--RGELNDKLIWA----FQLYDLDNNGL 115 A E F DA+ +GY+ E + + DK+ A ++ D +++G Sbjct: 6 KAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGK 65 Query: 116 ISYDEMLR 123 IS +E L Sbjct: 66 ISKEEFLN 73 Score = 32.3 bits (72), Expect = 0.15, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 26/70 (37%), Gaps = 6/70 (8%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFG-----DPSAFAEYVFNVFDADKNG 78 K EL+ +K + G++ E Q + + + + D + +G Sbjct: 6 KAELEAAFKKLDAN-GDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDG 64 Query: 79 YIDFKEFICA 88 I +EF+ A Sbjct: 65 KISKEEFLNA 74 >5JOJ-A nrPDB Length = 97 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 8/72 (11%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 +L AF D D NG IS++E+ + A LP + + D + Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAAC--------LPLPGYRVREITENLMATGDLD 64 Query: 160 KDGQLTLEEFCE 171 +DG+++ +EF + Sbjct: 65 QDGRISFDEFIK 76 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 27/69 (39%), Gaps = 4/69 (5%) Query: 64 FAEYVFNVFDADKNGYIDFKE----FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 F D D NGYI F E F A + + DLD +G IS+D Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFD 72 Query: 120 EMLRIVDAI 128 E ++I + Sbjct: 73 EFIKIFHGL 81 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 34/92 (36%), Gaps = 4/92 (4%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF---FPFGDPSAFAEYVFNVFDA 74 + + EL++ + D +G+++ +E ++K P E + D Sbjct: 5 SVSDEEMMELREAFAKVDTD-GNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDL 63 Query: 75 DKNGYIDFKEFICALSVTSRGELNDKLIWAFQ 106 D++G I F EFI ++ A Sbjct: 64 DQDGRISFDEFIKIFHGLKSTDVAKTFRKAIN 95 >1QXP-A nrPDB Length = 900 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 30/192 (15%), Positives = 57/192 (29%), Gaps = 28/192 (14%) Query: 5 QSKLSQDQLQDLVRSTRFDKKELQQWYK-GFFKDCPSGH-LNKSEFQKIY-------KQF 55 +L +L ++E+ +K F K ++ E Q I K Sbjct: 510 TQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDMEISVKELQTILNRIISKHKDL 569 Query: 56 FPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGL 115 G + N+ D D NG + EF + F+ +DLD +G Sbjct: 570 RTNGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLT------IFRKFDLDKSGS 623 Query: 116 ISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 +S EM ++A + + + +++ + + F R Sbjct: 624 MSAYEMRMAIEAAGFKLPCQLHQVIVARFAD---DELI----------IDFDNFVRCLVR 670 Query: 176 DPTIVSALSLYD 187 + D Sbjct: 671 LEILFKIFKQLD 682 Score = 39.6 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 33/89 (37%), Gaps = 9/89 (10%) Query: 28 QQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFIC 87 Q YK F D SG + +E ++ + ++ + D N +DF FI Sbjct: 807 QGIYKRFETD-RSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDETGN--MDFDNFIS 863 Query: 88 ALSVTSRGELNDKLIWAFQLYDLDNNGLI 116 L D + AF+ D + G I Sbjct: 864 CLVRL------DAMFRAFRSLDKNGTGQI 886 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 23/113 (20%), Positives = 48/113 (42%), Gaps = 7/113 (6%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQ-LYDL--DNNGLI 116 +P+ +++ F K G + + I A + +++ F+ L+ ++ I Sbjct: 491 EPNKEGDFLLRFFSEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDMEI 550 Query: 117 SYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 S E+ I++ I S K + + N+MD++ +G+L L EF Sbjct: 551 SVKELQTILNRII----SKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEF 599 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 28/165 (16%), Positives = 55/165 (33%), Gaps = 25/165 (15%) Query: 30 WYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL 89 ++ F D SG ++ E + + V AD IDF F+ L Sbjct: 612 IFRKFDLD-KSGSMSAYEMRMAIEAAGFKLPCQL--HQVIVARFADDELIIDFDNFVRCL 668 Query: 90 SVTSRGELNDKLIWAFQLYDLDNNGLISYD-----------EMLRIVDAIYKMVGSMVKL 138 + L F+ D +N G I D ++ ++ + + Sbjct: 669 VRL------EILFKIFKQLDPENTGTIQLDLISWLSFSVLGKLAAAIEHHHHHHMHYSNI 722 Query: 139 PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC----EGSKRDPTI 179 +E E++ K+F + + D +++ E + R P + Sbjct: 723 EANESEEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDL 766 Score = 36.5 bits (83), Expect = 0.008, Method: Composition-based stats. Identities = 24/184 (13%), Positives = 65/184 (35%), Gaps = 34/184 (18%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFF---PFGDPSAF----AEYV 68 + + ++++ ++ + ++ +E I + P F + Sbjct: 722 IEANESEEERQFRKLFVQLA--GDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSM 779 Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 V D+D G + F+EF + + + ++ ++ D +G I +E+ +A Sbjct: 780 VAVMDSDTTGKLGFEEFKYLWNNIKKWQG------IYKRFETDRSGTIGSNELPGAFEAA 833 Query: 129 YKMVGSMVKLPEDEDTPEK--------------RVNKIFNMM---DKNKDGQL--TLEEF 169 + + ++ R++ +F DKN GQ+ ++E+ Sbjct: 834 GFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEW 893 Query: 170 CEGS 173 + + Sbjct: 894 LQLT 897 Score = 26.5 bits (57), Expect = 7.7, Method: Composition-based stats. Identities = 13/99 (13%), Positives = 28/99 (28%), Gaps = 17/99 (17%) Query: 107 LYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTP-----------------EKRV 149 + D D G + ++E + + I K G + D + + Sbjct: 782 VMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFETDRSGTIGSNELPGAFEAAGFHLNQHI 841 Query: 150 NKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDG 188 + ++ G + + F R + A D Sbjct: 842 YSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDK 880 >3KPX-A nrPDB Length = 198 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 30/58 (51%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 E VF++FD D +G I E+ ++ ++ F+ DLDN+G + DEM R Sbjct: 119 EAVFDIFDKDGSGSISLDEWKTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEMTR 176 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 25/155 (16%), Positives = 48/155 (30%), Gaps = 32/155 (20%) Query: 34 FFKDCPSGHLNKSEFQ-----KIYKQFFPFGDPSAFAEYVFNVFDA----DKNGYIDFKE 84 F +G + E I + + + F D ++F Sbjct: 31 FLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYGKEVEFPA 90 Query: 85 FI-----------CALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVG 133 F+ S + + + F ++D D +G IS DE +K G Sbjct: 91 FVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDE--------WKTYG 142 Query: 134 SMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEE 168 + + ++ K F D + G+L ++E Sbjct: 143 GISGICPS----DEDAEKTFKHCDLDNSGKLDVDE 173 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 45/116 (38%), Gaps = 13/116 (11%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVT---------SRGELNDKLIWAFQLYDLDNNGLI 116 +++FN D + NG I E + S ++ + + + + AF + Sbjct: 26 KFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAF--FKKIGLDYG 83 Query: 117 SYDEMLRIVDAIYKMVGSMVKL--PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 E V+ ++ +KL + +F++ DK+ G ++L+E+ Sbjct: 84 KEVEFPAFVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEWK 139 Score = 35.8 bits (81), Expect = 0.012, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 28/74 (37%), Gaps = 2/74 (2%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 + F D++ NG I+ DE+ + A + + P ++ V F + + Sbjct: 26 KFMFNFLDINGNGKITLDEI--VSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYG 83 Query: 162 GQLTLEEFCEGSKR 175 ++ F G K Sbjct: 84 KEVEFPAFVNGWKE 97 Score = 26.5 bits (57), Expect = 7.1, Method: Composition-based stats. Identities = 9/25 (36%), Positives = 16/25 (64%) Query: 152 IFNMMDKNKDGQLTLEEFCEGSKRD 176 +FN +D N +G++TL+E + D Sbjct: 28 MFNFLDINGNGKITLDEIVSKASDD 52 >5JOL-A nrPDB Length = 82 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 8/72 (11%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 +L AF D D NG IS++E+ + A LP + + D + Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAAC--------LPLPGYRVREITENLMATGDLD 64 Query: 160 KDGQLTLEEFCE 171 +DG+++ +EF + Sbjct: 65 QDGRISFDEFIK 76 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 27/69 (39%), Gaps = 4/69 (5%) Query: 64 FAEYVFNVFDADKNGYIDFKE----FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 F D D NGYI F E F A + + DLD +G IS+D Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFD 72 Query: 120 EMLRIVDAI 128 E ++I + Sbjct: 73 EFIKIFHGL 81 Score = 33.8 bits (76), Expect = 0.045, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 31/72 (43%), Gaps = 4/72 (5%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF---FPFGDPSAFAEYVFNVFDA 74 + + EL++ + D +G+++ +E ++K P E + D Sbjct: 5 SVSDEEMMELREAFAKVDTD-GNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDL 63 Query: 75 DKNGYIDFKEFI 86 D++G I F EFI Sbjct: 64 DQDGRISFDEFI 75 >2OPO-A nrPDB Length = 86 Score = 50.8 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 34/83 (40%), Gaps = 13/83 (15%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 F+ +D + +G IS E+ + + V ++ +D + D Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLG-------------SVTPDEVRRMMAEIDTDGD 60 Query: 162 GQLTLEEFCEGSKRDPTIVSALS 184 G ++ +EF + ++ + +V +S Sbjct: 61 GFISFDEFTDFARANRGLVKDVS 83 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 29/72 (40%), Gaps = 1/72 (1%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 E +F FD + +G I E AL D++ D D +G IS+DE Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLGS-VTPDEVRRMMAEIDTDGDGFISFDEFTDFA 72 Query: 126 DAIYKMVGSMVK 137 A +V + K Sbjct: 73 RANRGLVKDVSK 84 Score = 43.1 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 31/83 (37%), Gaps = 4/83 (4%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 T D + ++ +K F + G ++ SE K + D D Sbjct: 3 AEDTPQDIADRERIFKRFDTN-GDGKISSSELGDALKTLGSVTP--DEVRRMMAEIDTDG 59 Query: 77 NGYIDFKEFICALSVTSRGELND 99 +G+I F EF + +RG + D Sbjct: 60 DGFISFDEFTDF-ARANRGLVKD 81 >1SR6-C nrPDB Length = 156 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 34/168 (20%), Positives = 69/168 (41%), Gaps = 25/168 (14%) Query: 18 RSTRFDKKELQQWYKGFFK-DCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 + ++ + +L+ ++ F D G ++ + + + + E VF V K Sbjct: 2 KLSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLG----INPRNEDVFAVGGTHK 57 Query: 77 NG--YIDFKEFICA---LSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 G + F+EF+ A L +G D + AF+ +D + G IS E+ ++ A+ Sbjct: 58 MGEKSLPFEEFLPAYEGLMDCEQGTFADYME-AFKTFDREGQGFISGAELRHVLTALG-- 114 Query: 132 VGSMVKLPEDEDTPEKRVNKIFNMMDKNKD--GQLTLEEFCEGSKRDP 177 E ++ V++I + D +D G + E+F + P Sbjct: 115 ----------ERLSDEDVDEIIKLTDLQEDLEGNVKYEDFVKKVMAGP 152 >3JAX-C nrPDB Length = 151 Score = 50.4 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 18/160 (11%), Positives = 57/160 (35%), Gaps = 18/160 (11%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFN-VFDADKNG 78 + E ++ ++ F + G + S+ + + + + + N D Sbjct: 5 SEEQTAEFKEAFQLFDR-TGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLK 63 Query: 79 YIDFKEFICALSVTSRGELN---DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 + F++F+ + ++ + + + +++D + NG + E+ ++ + Sbjct: 64 TLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLG------ 117 Query: 136 VKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E E+ V ++ ++ +G + EE Sbjct: 118 ------EKMTEEEVEQLVAGH-EDSNGCINYEELVRMVLS 150 >4P5X-A nrPDB Length = 315 Score = 50.4 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 28/158 (17%), Positives = 57/158 (36%), Gaps = 18/158 (11%) Query: 23 DKKELQQWYKGFFKDCPSG--HLNKSEFQKIYKQFFPFGDPSA-FAEYVFNVFDADKNGY 79 D EL+ + + G ++ +F + Y + + + + + V D K+G Sbjct: 16 DPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGL 75 Query: 80 IDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLP 139 I ++EF+ SV + I AFQL+D NG ++++ + I Sbjct: 76 ISYQEFLAFESVLCAPDSM--FIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFN-- 131 Query: 140 EDEDTPEKRVN-KIFNM-MDKNKDGQLTLEEFCEGSKR 175 + + + N+ L EF + + Sbjct: 132 ---------WDCEFIRLHFGHNRKKHLNYTEFTQFLQE 160 Score = 33.5 bits (75), Expect = 0.054, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 39/141 (27%), Gaps = 38/141 (26%) Query: 27 LQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK--- 83 + Q G G ++ EF P + F +FD NG + F+ Sbjct: 60 IVQLLAGVADQTKDGLISYQEFLAFESVLCA---PDSMFIVAFQLFDKSGNGEVTFENVK 116 Query: 84 ------------------EFICA--------------LSVTSRGELNDKLIWAFQLYDLD 111 EFI + + + AF L D Sbjct: 117 EIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKS 176 Query: 112 NNGLISYDEMLRIVDAIYKMV 132 +G+IS + I+ I + Sbjct: 177 KSGMISGLDFSDIMVTIRSHM 197 >2VRG-A nrPDB Length = 124 Score = 50.4 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 32/70 (45%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F+++D D N L+ E+ + ++K GS ED ++ + DKN DG + Sbjct: 55 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 114 Query: 165 TLEEFCEGSK 174 EF + + Sbjct: 115 DYAEFAKSLQ 124 Score = 28.4 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 30/83 (36%), Gaps = 11/83 (13%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQK----IYKQFFPFGDPSAFAEYVFNVFD- 73 +ELQ Y + L+ E ++K+ P + + N+ D Sbjct: 42 EAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDG 101 Query: 74 ------ADKNGYIDFKEFICALS 90 + +GYID+ EF +L Sbjct: 102 VLRDDDKNNDGYIDYAEFAKSLQ 124 >1JF0-A nrPDB Length = 195 Score = 50.4 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 29/58 (50%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 + VF++FD D +G I E+ ++ + FQ DLDN+G + DEM R Sbjct: 116 DAVFDIFDKDGSGTITLDEWKAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDEMTR 173 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 22/155 (14%), Positives = 42/155 (27%), Gaps = 32/155 (20%) Query: 34 FFKDCPSGHLNKSEFQKIYK----QFFPFGDPSAFAEYVFNVFDADKNG-----YIDFKE 84 + +G + E + G F E Sbjct: 28 YLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCVEAFFRGCGLEYGKETKFPE 87 Query: 85 FICAL-----------SVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVG 133 F+ + + + F ++D D +G I+ DE +K G Sbjct: 88 FLEGWKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDE--------WKAYG 139 Query: 134 SMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEE 168 + + E + K F D + G+L ++E Sbjct: 140 RISGISPSE----EDCEKTFQHCDLDNSGELDVDE 170 Score = 32.7 bits (73), Expect = 0.11, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 47/120 (39%), Gaps = 21/120 (17%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVT---------SRGELNDKLIWAFQLYDLDNNGL- 115 +++F+ D + NG I E + S ++ + + + AF GL Sbjct: 23 KFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCVEAF----FRGCGLE 78 Query: 116 ----ISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRV-NKIFNMMDKNKDGQLTLEEFC 170 + E L + + K +E T + + +F++ DK+ G +TL+E+ Sbjct: 79 YGKETKFPEFLEGWKNLA--NADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWK 136 Score = 31.9 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 27/73 (36%), Gaps = 2/73 (2%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 + F D++ NG I+ DE+ + A + ++ P + V F Sbjct: 23 KFMFDYLDINGNGQITLDEI--VSKASDDICKNLGATPAQTQRHQDCVEAFFRGCGLEYG 80 Query: 162 GQLTLEEFCEGSK 174 + EF EG K Sbjct: 81 KETKFPEFLEGWK 93 Score = 27.3 bits (59), Expect = 3.8, Method: Composition-based stats. Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 4/50 (8%) Query: 136 VKLPEDEDTPE--KRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSAL 183 VKL D D P+ KR +F+ +D N +GQ+TL+E SK I L Sbjct: 7 VKLQTDFDNPKWIKRHKFMFDYLDINGNGQITLDEIV--SKASDDICKNL 54 >1ZMZ-A nrPDB Length = 98 Score = 50.0 bits (118), Expect = 5e-07, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 37/94 (39%), Gaps = 5/94 (5%) Query: 1 MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD 60 M S + +L T K+E+++ + F D +G ++ E + + F Sbjct: 10 MASSSQRKRMSPKPEL---TEEQKQEIREAFDLFDAD-GTGTIDVKELKVAMRAL-GFEP 64 Query: 61 PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSR 94 + + + D + G ++F +F+ ++ Sbjct: 65 KKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMS 98 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 28/67 (41%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 + F++FDAD G ID KE A+ +++ D + G +++ Sbjct: 28 EQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFG 87 Query: 120 EMLRIVD 126 + L ++ Sbjct: 88 DFLTVMT 94 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 29/76 (38%), Gaps = 12/76 (15%) Query: 98 NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMD 157 ++ AF L+D D G I E+ + A+ ++ + K+ + +D Sbjct: 30 KQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPK------------KEEIKKMISEID 77 Query: 158 KNKDGQLTLEEFCEGS 173 K G++ +F Sbjct: 78 KEGTGKMNFGDFLTVM 93 >2K2A-A nrPDB Length = 70 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 12/77 (15%) Query: 97 LNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMM 156 + +L AF+LYD + NG IS D M I+ + DE + ++ + + + Sbjct: 1 MQQELREAFRLYDKEGNGYISTDVMREILAEL------------DETLSSEDLDAMIDEI 48 Query: 157 DKNKDGQLTLEEFCEGS 173 D + G + EEF Sbjct: 49 DADGSGTVDFEEFMGVM 65 Score = 43.5 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 37/67 (55%), Gaps = 2/67 (2%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 ++EL++ ++ + K+ +G+++ ++I + + + + DAD +G +DF+ Sbjct: 2 QQELREAFRLYDKE-GNGYISTDVMREILAELDETLSSEDL-DAMIDEIDADGSGTVDFE 59 Query: 84 EFICALS 90 EF+ ++ Sbjct: 60 EFMGVMT 66 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 25/65 (38%) Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 F ++D + NGYI L+ ++ L D D +G + ++E Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEF 61 Query: 122 LRIVD 126 + ++ Sbjct: 62 MGVMT 66 >3LCP-C nrPDB Length = 93 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 32/70 (45%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F+++D D N L+ E+ + ++K GS ED ++ + DKN DG + Sbjct: 24 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 83 Query: 165 TLEEFCEGSK 174 EF + + Sbjct: 84 DYAEFAKSLQ 93 Score = 28.4 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 30/83 (36%), Gaps = 11/83 (13%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQK----IYKQFFPFGDPSAFAEYVFNVFD- 73 +ELQ Y + L+ E ++K+ P + + N+ D Sbjct: 11 EAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDG 70 Query: 74 ------ADKNGYIDFKEFICALS 90 + +GYID+ EF +L Sbjct: 71 VLRDDDKNNDGYIDYAEFAKSLQ 93 >3A4U-B nrPDB Length = 143 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 32/70 (45%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F+++D D N L+ E+ + ++K GS ED ++ + DKN DG + Sbjct: 74 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 133 Query: 165 TLEEFCEGSK 174 EF + + Sbjct: 134 DYAEFAKSLQ 143 Score = 28.4 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 30/83 (36%), Gaps = 11/83 (13%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQK----IYKQFFPFGDPSAFAEYVFNVFD- 73 +ELQ Y + L+ E ++K+ P + + N+ D Sbjct: 61 EAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDG 120 Query: 74 ------ADKNGYIDFKEFICALS 90 + +GYID+ EF +L Sbjct: 121 VLRDDDKNNDGYIDYAEFAKSLQ 143 >2KSZ-A nrPDB Length = 76 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 35/74 (47%), Gaps = 12/74 (16%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 AF L+D D +G I+ +E+ ++ ++ D++ E+ + + + +D + + Sbjct: 13 KEAFGLFDKDGDGCITVEELATVIRSL------------DQNPTEEELQDMISEVDADGN 60 Query: 162 GQLTLEEFCEGSKR 175 G + +EF + Sbjct: 61 GTIEFDEFLSLMAK 74 Score = 46.9 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 29/74 (39%), Gaps = 2/74 (2%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 + + ++ + F KD G + E + + + + + DAD NG Sbjct: 4 LSEEQIVDFKEAFGLFDKD-GDGCITVEELATVIRSLDQNPTEEELQD-MISEVDADGNG 61 Query: 79 YIDFKEFICALSVT 92 I+F EF+ ++ Sbjct: 62 TIEFDEFLSLMAKK 75 Score = 46.9 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 27/60 (45%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125 + F +FD D +G I +E + + ++L D D NG I +DE L ++ Sbjct: 13 KEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLM 72 >6MI5-X nrPDB Length = 117 Score = 50.0 bits (118), Expect = 7e-07, Method: Composition-based stats. Identities = 26/102 (25%), Positives = 38/102 (37%), Gaps = 13/102 (12%) Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML-RIVDA 127 FD DK+G ID KE + A S AF D D +G + E+ R+ +A Sbjct: 9 IAAFDPDKDGTIDLKEALAAGSA------------AFDKLDPDKDGTLDAKELKGRVSEA 56 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 K + D+ V F + + DG + E Sbjct: 57 DLKKLDPDNDGTLDKKEYLAAVEAQFKAANPDNDGTIDAREL 98 Score = 33.1 bits (74), Expect = 0.067, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 36/108 (33%), Gaps = 26/108 (24%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPS--GHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDA 74 T K+ L F K P G L+ E + +E D Sbjct: 16 KDGTIDLKEALAAGSAAFDKLDPDKDGTLDAKELK------------GRVSEADLKKLDP 63 Query: 75 DKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 D +G +D KE++ A + F+ + DN+G I E+ Sbjct: 64 DNDGTLDKKEYLAA------------VEAQFKAANPDNDGTIDARELA 99 >1O1A-B nrPDB Length = 145 Score = 50.0 bits (118), Expect = 7e-07, Method: Composition-based stats. Identities = 20/160 (12%), Positives = 53/160 (33%), Gaps = 19/160 (11%) Query: 22 FDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 FD+ E++ + + F G ++K + ++ + + + + + +G Sbjct: 1 FDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMI----KEASGP 56 Query: 80 IDFKEFICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKL 138 I+F F+ +G + +I AF++ D D G I + ++ Sbjct: 57 INFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTP---- 112 Query: 139 PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPT 178 + + ++ + G + + C Sbjct: 113 --------EEIKNMWAAFPPDVAGNVDYKNICYVITHGED 144 Score = 31.1 bits (69), Expect = 0.32, Method: Composition-based stats. Identities = 13/96 (13%), Positives = 34/96 (35%), Gaps = 22/96 (22%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 + AF + D + +G+I D++ A+ ++ + + ++ + Sbjct: 7 EDFKEAFTVIDQNADGIIDKDDLRETFAAMGRL-----------NVKNEELDAMIKEA-- 53 Query: 159 NKDGQLTLEEF-------CEGSKRDPTIVSALSLYD 187 G + F +G+ + I+ A + D Sbjct: 54 --SGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLD 87 >1H4B-A nrPDB Length = 84 Score = 49.6 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 12/82 (14%), Positives = 31/82 (37%), Gaps = 13/82 (15%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + F+ +D + +G IS E+ + + V + +D + Sbjct: 10 ERERIFKRFDANGDGKISAAELGEALKTLG-------------SITPDEVKHMMAEIDTD 56 Query: 160 KDGQLTLEEFCEGSKRDPTIVS 181 DG ++ +EF + + + ++ Sbjct: 57 GDGFISFQEFTDFGRANRGLLK 78 Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 25/64 (39%), Gaps = 1/64 (1%) Query: 58 FGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLIS 117 A E +F FDA+ +G I E AL D++ D D +G IS Sbjct: 4 HPQDKAERERIFKRFDANGDGKISAAELGEALKTLGS-ITPDEVKHMMAEIDTDGDGFIS 62 Query: 118 YDEM 121 + E Sbjct: 63 FQEF 66 >6IIE-A nrPDB Length = 93 Score = 49.6 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 3/91 (3%) Query: 95 GELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFN 154 G DKL + F+LYD D NG++ E+ +I I +M+ L D + ++ Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKI---ILQMMRVAEYLDWDVSELRPILQEMMK 61 Query: 155 MMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 +D + G ++ E+ ++ L L Sbjct: 62 EIDYDGSGSVSQAEWVRAGATTVPLLVLLGL 92 Score = 29.6 bits (65), Expect = 0.92, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 29/81 (35%), Gaps = 11/81 (13%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFF--------PFGDPSAFAEY 67 + DK E +K + D +G L+ SE KI Q + + Sbjct: 2 MEGGRPEDKLEFT--FKLYDTD-RNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQE 58 Query: 68 VFNVFDADKNGYIDFKEFICA 88 + D D +G + E++ A Sbjct: 59 MMKEIDYDGSGSVSQAEWVRA 79 >5Z1Q-A nrPDB Length = 95 Score = 49.6 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 31/67 (46%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 + + F++FD +K G ID+ E A+ +++ YD + NG I +D Sbjct: 24 EQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFD 83 Query: 120 EMLRIVD 126 + L I+ Sbjct: 84 DFLDIMT 90 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 37/87 (42%), Gaps = 2/87 (2%) Query: 8 LSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEY 67 + + + + K+E+++ + F + +G ++ E + + F Sbjct: 10 MQPPKKRVRQELSEEQKQEIKEAFDLFDTN-KTGSIDYHELKVAMRAL-GFDVKKPEILE 67 Query: 68 VFNVFDADKNGYIDFKEFICALSVTSR 94 + N +D + NGYI F +F+ ++ + Sbjct: 68 LMNEYDREGNGYIGFDDFLDIMTEKIK 94 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 36/100 (36%), Gaps = 18/100 (18%) Query: 80 IDFKEFICA------LSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVG 133 I EF + E ++ AF L+D + G I Y E+ + A+ Sbjct: 2 IKKPEFGLMQPPKKRVRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALG---- 57 Query: 134 SMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 D + + ++ N D+ +G + ++F + Sbjct: 58 --------FDVKKPEILELMNEYDREGNGYIGFDDFLDIM 89 Score = 26.9 bits (58), Expect = 5.1, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 24/54 (44%), Gaps = 6/54 (11%) Query: 140 EDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK------RDPTIVSALSLYD 187 E + ++ + + F++ D NK G + E + + P I+ ++ YD Sbjct: 20 ELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYD 73 >2K2I-A nrPDB Length = 79 Score = 49.6 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 42/83 (50%), Gaps = 12/83 (14%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 S + ++++ AF+L+D D G IS+ + R+ + E+ ++ + ++ Sbjct: 5 SEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELG------------ENLTDEELQEM 52 Query: 153 FNMMDKNKDGQLTLEEFCEGSKR 175 + D++ DG+++ +EF K+ Sbjct: 53 IDEADRDGDGEVSEQEFLRIMKK 75 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 27/75 (36%) Query: 54 QFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNN 113 Q D F +FD D+ G I FK +++L D D + Sbjct: 2 QKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGD 61 Query: 114 GLISYDEMLRIVDAI 128 G +S E LRI+ Sbjct: 62 GEVSEQEFLRIMKKT 76 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 K+E+ + +K F D +G ++ +++ K+ E + + D D +G + Sbjct: 9 TKEEILKAFKLFDDD-ETGKISFKNLKRVAKELGENLTDEELQE-MIDEADRDGDGEVSE 66 Query: 83 KEFICALSVTS 93 +EF+ + TS Sbjct: 67 QEFLRIMKKTS 77 >1S36-A nrPDB Length = 195 Score = 49.6 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 39/96 (40%), Gaps = 4/96 (4%) Query: 28 QQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFIC 87 + + F L SE +K + + + VF++FD D +G I E+ Sbjct: 82 EIAFPQFLDGFK--QLATSELKKWARNEPTL--IREWGDAVFDIFDKDGSGTITLDEWKA 137 Query: 88 ALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 ++ + F+ DLDN+G + DEM R Sbjct: 138 YGKISGISPSQEDCEATFRHCDLDNSGDLDVDEMTR 173 Score = 33.8 bits (76), Expect = 0.049, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 47/120 (39%), Gaps = 21/120 (17%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVT---------SRGELNDKLIWAFQLYDLDNNG-- 114 +++F+ D + NG I E + S + + + + AF G Sbjct: 23 KHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAF----FRGCGME 78 Query: 115 ---LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRV-NKIFNMMDKNKDGQLTLEEFC 170 I++ + L + + K +E T + + +F++ DK+ G +TL+E+ Sbjct: 79 YGKEIAFPQFLDGFKQLA--TSELKKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWK 136 Score = 28.1 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 2/43 (4%) Query: 136 VKLPEDEDTPE--KRVNKIFNMMDKNKDGQLTLEEFCEGSKRD 176 VKL D D P KR +F+ +D N +G++TL+E + D Sbjct: 7 VKLKTDFDNPRWIKRHKHMFDFLDINGNGKITLDEIVSKASDD 49 >3AKA-A nrPDB Length = 166 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 31/81 (38%), Gaps = 3/81 (3%) Query: 98 NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDT---PEKRVNKIFN 154 ++ F +D D NG I + A+ G + + E + Sbjct: 3 ERRIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAG 62 Query: 155 MMDKNKDGQLTLEEFCEGSKR 175 + D++ D ++T EEF G+ + Sbjct: 63 IADRDGDQRITREEFVTGAVK 83 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 59/169 (34%), Gaps = 38/169 (22%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFP--------------FGDPSAFAEYVF 69 ++ + + F +D +GH+++S+F K +G A + + Sbjct: 3 ERRIAARFTTFDQD-GNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLA 61 Query: 70 NVFDADKNGYIDFKEFICALSVTSRGELNDK--------LIWAFQLYDLDNNGLISYDEM 121 + D D + I +EF+ R + D+ L A + D D +G ++ + Sbjct: 62 GIADRDGDQRITREEFVTGAVKRLRDK-PDRFAEIARPFLHAALGVADTDGDGAVTVADT 120 Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 R + A PE + +D + DG++ E Sbjct: 121 ARALTAFG--------------VPEDLARQAAAALDTDGDGKVGETEIV 155 >3MSE-B nrPDB Length = 180 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 50/157 (31%), Gaps = 27/157 (17%) Query: 27 LQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFI 86 + + + + +G L+ E IY G + D + G I + EF+ Sbjct: 41 INELFYKLDTN-HNGSLSHRE---IYTVLASVGIKKWDINRILQALDINDRGNITYTEFM 96 Query: 87 CALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPE 146 E L AF D D +G IS ++ V L D+ Sbjct: 97 AGCYRWKNIEST-FLKAAFNKIDKDEDGYISKSDI--------------VSLVHDKVLDN 141 Query: 147 KRVNKIFNMMDKNKDG--------QLTLEEFCEGSKR 175 ++ F + K G +++ +EF + Sbjct: 142 NDIDNFFLSVHSIKKGIPREHIINKISFQEFKDYMLS 178 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 42/111 (37%), Gaps = 15/111 (13%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 + +F D + NG + +E L+ + + + Q D+++ G I+Y E Sbjct: 39 KYINELFYKLDTNHNGSLSHREIYTVLASVGIKKWD--INRILQALDINDRGNITYTEF- 95 Query: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 M G ++ + FN +DK++DG ++ + Sbjct: 96 --------MAGCYRW----KNIESTFLKAAFNKIDKDEDGYISKSDIVSLV 134 Score = 36.2 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 33/83 (39%), Gaps = 14/83 (16%) Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNK 160 + F D ++NG +S+ E+ ++ ++ + +N+I +D N Sbjct: 41 INELFYKLDTNHNGSLSHREIYTVLASVG--------------IKKWDINRILQALDIND 86 Query: 161 DGQLTLEEFCEGSKRDPTIVSAL 183 G +T EF G R I S Sbjct: 87 RGNITYTEFMAGCYRWKNIESTF 109 >2M8U-A nrPDB Length = 77 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 34/81 (41%), Gaps = 12/81 (14%) Query: 90 SVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRV 149 S + ++I AF+++D D NG ++ D + ++++ + M+ P + Sbjct: 2 SHMNHINTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMM------------PADEI 49 Query: 150 NKIFNMMDKNKDGQLTLEEFC 170 ++ D G + E F Sbjct: 50 EEMIYEADPQNSGYVQYETFV 70 Score = 31.1 bits (69), Expect = 0.31, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 26/70 (37%) Query: 56 FPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGL 115 + A F VFD D NGY+ L+ D++ D N+G Sbjct: 4 MNHINTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSGY 63 Query: 116 ISYDEMLRIV 125 + Y+ + ++ Sbjct: 64 VQYETFVGML 73 >4YGB-B nrPDB Length = 104 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 35/85 (41%), Gaps = 1/85 (1%) Query: 91 VTSRGELNDKL-IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRV 149 +L + F+++D D N L+ E+ + ++K GS ED + Sbjct: 20 RHMLEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINII 79 Query: 150 NKIFNMMDKNKDGQLTLEEFCEGSK 174 + + DKN DG + EF + + Sbjct: 80 DGVLRDDDKNNDGYIDYAEFAKSLQ 104 Score = 27.3 bits (59), Expect = 4.4, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 30/81 (37%), Gaps = 11/81 (13%) Query: 21 RFDKKELQQWYKGFFKDCPSGHLNKSEFQK----IYKQFFPFGDPSAFAEYVFNVFD--- 73 +ELQ Y + L+ E ++K+ P + + N+ D Sbjct: 24 EMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVL 83 Query: 74 ----ADKNGYIDFKEFICALS 90 + +GYID+ EF +L Sbjct: 84 RDDDKNNDGYIDYAEFAKSLQ 104 >1SL8-A nrPDB Length = 191 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 35/82 (42%), Gaps = 2/82 (2%) Query: 42 HLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKL 101 L E ++ K + + +F++ D D+NG I E+ + ++ Sbjct: 90 RLASEELKRYSKNQITL--IRLWGDALFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDC 147 Query: 102 IWAFQLYDLDNNGLISYDEMLR 123 F++ D+D +G + DEM R Sbjct: 148 EETFRVCDIDESGQLDVDEMTR 169 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 25/64 (39%), Gaps = 12/64 (18%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F + D D NG IS DE + + + + F + D ++ GQL Sbjct: 115 FDIIDKDQNGAISLDEWKAYTKSAGII------------QSSEDCEETFRVCDIDESGQL 162 Query: 165 TLEE 168 ++E Sbjct: 163 DVDE 166 Score = 33.1 bits (74), Expect = 0.071, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 49/121 (40%), Gaps = 13/121 (10%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVT---------SRGELNDKLIWAFQLYDLDNNGLI 116 +++FN D + NG I E + S + + + + AF + Sbjct: 19 KHMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAF--FGGAGMKYG 76 Query: 117 SYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRV--NKIFNMMDKNKDGQLTLEEFCEGSK 174 E ++ ++ +K R+ + +F+++DK+++G ++L+E+ +K Sbjct: 77 VETEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEWKAYTK 136 Query: 175 R 175 Sbjct: 137 S 137 >5XND-A nrPDB Length = 114 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 37/97 (38%), Gaps = 11/97 (11%) Query: 78 GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 G D K+F A ++ + D++ AF + D D +G I +E+ + + Sbjct: 28 GSFDHKKFFKACGLSGKST--DEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARA--- 82 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 + D + DG++ ++EF K Sbjct: 83 ------LSDAETKAFLKAGDSDGDGKIGIDEFAAMIK 113 Score = 42.7 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 3/81 (3%) Query: 49 QKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE---FICALSVTSRGELNDKLIWAF 105 +K +K G + + F + D DK+G+I+ +E F+ +R + + Sbjct: 33 KKFFKACGLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFL 92 Query: 106 QLYDLDNNGLISYDEMLRIVD 126 + D D +G I DE ++ Sbjct: 93 KAGDSDGDGKIGIDEFAAMIK 113 >1GGW-A nrPDB Length = 140 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 19/152 (12%), Positives = 56/152 (36%), Gaps = 22/152 (14%) Query: 28 QQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFIC 87 +Q + F + +G + K+ + + + ++ +D ++F+ Sbjct: 8 KQAFSLFDRH-GTGRIPKTSIGDLLRACGQNPTLAE-----ITEIESTLPAEVDMEQFLQ 61 Query: 88 ALSV---TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDT 144 L+ ++ + FQ++D D G+I E+ ++ ++ E Sbjct: 62 VLNRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVLTSLG------------EKL 109 Query: 145 PEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRD 176 + ++++ + KDG + +F + + Sbjct: 110 SNEEMDELLKGVPV-KDGMVNYHDFVQMILAN 140 >4NQG-A nrPDB Length = 197 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 26/58 (44%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 + +F++ D D NG + E+I + + F DLD +G + DEM R Sbjct: 117 DALFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDEMTR 174 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 47/157 (29%), Gaps = 36/157 (22%) Query: 34 FFKDCPSGHLNKSEFQ-----KIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF------ 82 F +G +N +E I K+ + + + F +++ Sbjct: 29 FLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVEDFF--GGAGLEYDKDTTW 86 Query: 83 KEFICALSVTSRGELNDKLI-----------WAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 E+I ++ EL F + D D NG +S DE ++ Sbjct: 87 PEYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKDGNGSVSLDEWIQYTHCAGIQ 146 Query: 132 VGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEE 168 + F D + DG+L ++E Sbjct: 147 QSRG------------QCEATFAHCDLDGDGKLDVDE 171 Score = 35.0 bits (79), Expect = 0.019, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 48/117 (41%), Gaps = 13/117 (11%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSV---TSRGELNDKLIWAFQ-LYDLDNNGLISYDEM 121 +++FN D + NG I+ E + S G ++ + + D + YD Sbjct: 24 KHMFNFLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVEDFFGGAGLEYD-- 81 Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRV-------NKIFNMMDKNKDGQLTLEEFCE 171 Y + E E + RV + +F+++DK+ +G ++L+E+ + Sbjct: 82 KDTTWPEYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKDGNGSVSLDEWIQ 138 Score = 27.3 bits (59), Expect = 4.0, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 20/59 (33%), Gaps = 2/59 (3%) Query: 29 QWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFIC 87 + KD +G ++ E+ + Y E F D D +G +D E Sbjct: 118 ALFDIIDKD-GNGSVSLDEWIQ-YTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDEMTR 174 >5XOP-A nrPDB Length = 66 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 29/64 (45%) Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 AE +F D + +G + ++E +S + L F+ D D +G I ++E + Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKF 61 Query: 125 VDAI 128 +I Sbjct: 62 YGSI 65 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 31/71 (43%), Gaps = 12/71 (16%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 F+ D++ +G +SY+E+ V + E+ + IF +DK+ D Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN------------EQLLQLIFKSIDKDGD 50 Query: 162 GQLTLEEFCEG 172 G + EEF + Sbjct: 51 GFIDFEEFAKF 61 Score = 32.7 bits (73), Expect = 0.092, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 20/51 (39%), Gaps = 1/51 (1%) Query: 36 KDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFI 86 G ++ E + + + +F D D +G+IDF+EF Sbjct: 10 DVNGDGAVSYEEVKAFVSKKRAI-KNEQLLQLIFKSIDKDGDGFIDFEEFA 59 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 13/30 (43%) Query: 150 NKIFNMMDKNKDGQLTLEEFCEGSKRDPTI 179 +F +D N DG ++ EE + I Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAI 32 >1NYA-A nrPDB Length = 176 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 40/97 (41%), Gaps = 9/97 (9%) Query: 38 CPSGHLNKSEFQKIYKQF-FPFGDPS------AFAEYVFNVFDADKNGYIDFKEFICALS 90 G L + +F ++ + F G+ S + + + D + +G I+ EF L+ Sbjct: 70 GSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEFAAWLT 129 Query: 91 VTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 + + AF D + NG +S DE+L V Sbjct: 130 ALGMSKA--EAAEAFNQVDTNGNGELSLDELLTAVRD 164 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 25/69 (36%), Gaps = 3/69 (4%) Query: 33 GFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVT 92 G G +N EF G A A FN D + NG + E + A+ Sbjct: 109 GMCDKNADGQINADEFAAWLTAL---GMSKAEAAEAFNQVDTNGNGELSLDELLTAVRDF 165 Query: 93 SRGELNDKL 101 G L+ +L Sbjct: 166 HFGRLDVEL 174 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 26/116 (22%), Positives = 46/116 (39%), Gaps = 19/116 (16%) Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELND-------KLIWAFQ-LYD-------LDNN 113 F+ +D D NG ++ +F + D L AF L+D + ++ Sbjct: 13 FDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAKEAGVGSD 72 Query: 114 GLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 G ++ ++ +R+ + + G V I M DKN DGQ+ +EF Sbjct: 73 GSLTEEQFIRVTENLIFEQGEASFNRVLGPV----VKGIVGMCDKNADGQINADEF 124 Score = 34.6 bits (78), Expect = 0.024, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 27/66 (40%), Gaps = 14/66 (21%) Query: 109 DLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEE 168 D + +G I+ DE + A+ + + FN +D N +G+L+L+E Sbjct: 112 DKNADGQINADEFAAWLTALG--------------MSKAEAAEAFNQVDTNGNGELSLDE 157 Query: 169 FCEGSK 174 + Sbjct: 158 LLTAVR 163 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 30/80 (37%), Gaps = 5/80 (6%) Query: 98 NDKLIWAFQLYDLDNNGLISYDEM----LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIF 153 +D+L F +D D NG + + I +A K G+ ++ + + Sbjct: 6 SDRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTL-KNAFGGLFDYLA 64 Query: 154 NMMDKNKDGQLTLEEFCEGS 173 DG LT E+F + Sbjct: 65 KEAGVGSDGSLTEEQFIRVT 84 >5ZGM-A nrPDB Length = 110 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 38/96 (39%), Gaps = 11/96 (11%) Query: 78 GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 G D+K F + + +G+ ++ F++ D D +G I +E+ ++ Sbjct: 23 GTFDYKRFFQLVGL--KGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGR---- 76 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 D + + D + DG++ +EF + Sbjct: 77 -----DLSDTETKALLAAGDSDHDGKIGADEFAKMV 107 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 38/82 (46%), Gaps = 3/82 (3%) Query: 47 EFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL---SVTSRGELNDKLIW 103 ++++ ++ G A + VF + D D++G+I+ +E L S R + + Sbjct: 26 DYKRFFQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTETKA 85 Query: 104 AFQLYDLDNNGLISYDEMLRIV 125 D D++G I DE ++V Sbjct: 86 LLAAGDSDHDGKIGADEFAKMV 107 Score = 36.5 bits (83), Expect = 0.008, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 3/78 (3%) Query: 15 DLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD--PSAFAEYVFNVF 72 LV + ++++ ++ KD SG + + E + + K F G + + Sbjct: 32 QLVGLKGKSEAQVKEVFEILDKD-QSGFIEEEELKSVLKGFSAHGRDLSDTETKALLAAG 90 Query: 73 DADKNGYIDFKEFICALS 90 D+D +G I EF ++ Sbjct: 91 DSDHDGKIGADEFAKMVA 108 >1UHK-A nrPDB Length = 191 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 29/58 (50%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 + +F++ D D+NG I E+ + ++ F++ D+D +G + DEM R Sbjct: 112 DALFDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 25/64 (39%), Gaps = 12/64 (18%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F + D D NG I+ DE A + + + F + D ++ GQL Sbjct: 115 FDIVDKDQNGAITLDEWKAYTKAAGII------------QSSEDCEETFRVCDIDESGQL 162 Query: 165 TLEE 168 ++E Sbjct: 163 DVDE 166 Score = 33.8 bits (76), Expect = 0.049, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 53/120 (44%), Gaps = 11/120 (9%) Query: 66 EYVFNVFDADKNGYIDFKEFICALS---VTSRGELNDKLIW---AFQLYDLDNNGL---I 116 +++FN D + NG I E + S + + G ++ A + + G+ + Sbjct: 19 KHMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAF-FGGAGMKYGV 77 Query: 117 SYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRV-NKIFNMMDKNKDGQLTLEEFCEGSKR 175 D I + K ++E T + + +F+++DK+++G +TL+E+ +K Sbjct: 78 ETDWPAYIEGWKKLATDELEKYAKNEPTLIRIWGDALFDIVDKDQNGAITLDEWKAYTKA 137 >2JOJ-A nrPDB Length = 77 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 31/67 (46%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 + + F++FD +K G ID+ E A+ +++ YD + NG I +D Sbjct: 4 EQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFD 63 Query: 120 EMLRIVD 126 + L I+ Sbjct: 64 DFLDIMT 70 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 34/76 (44%), Gaps = 2/76 (2%) Query: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 + K+E+++ + F + +G ++ E + + F + N +D + NG Sbjct: 1 LSEEQKQEIKEAFDLFDTN-KTGSIDYHELKVAMRAL-GFDVKKPEILELMNEYDREGNG 58 Query: 79 YIDFKEFICALSVTSR 94 YI F +F+ ++ + Sbjct: 59 YIGFDDFLDIMTEKIK 74 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 31/76 (40%), Gaps = 12/76 (15%) Query: 98 NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMD 157 ++ AF L+D + G I Y E+ + A+ D + + ++ N D Sbjct: 6 KQEIKEAFDLFDTNKTGSIDYHELKVAMRALG------------FDVKKPEILELMNEYD 53 Query: 158 KNKDGQLTLEEFCEGS 173 + +G + ++F + Sbjct: 54 REGNGYIGFDDFLDIM 69 >5VE9-A nrPDB Length = 91 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 K + +++ KD G + + EF F V ++FD D +GYID+ Sbjct: 26 KSRVMDFFRRIDKD-QDGKITRQEFIDGI-LASKFPTTKLEMTAVADIFDRDGDGYIDYY 83 Query: 84 EFICALS 90 EF+ AL Sbjct: 84 EFVAALH 90 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 36/85 (42%), Gaps = 1/85 (1%) Query: 38 CPSGHLNKSEFQKIYKQFFPFGD-PSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGE 96 P GH+ +F K++ + + + F D D++G I +EFI + + Sbjct: 1 GPGGHMANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPT 60 Query: 97 LNDKLIWAFQLYDLDNNGLISYDEM 121 ++ ++D D +G I Y E Sbjct: 61 TKLEMTAVADIFDRDGDGYIDYYEF 85 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 25/66 (37%), Gaps = 12/66 (18%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F+ D D +G I+ E I ++ S + E T + D++ DG + Sbjct: 33 FRRIDKDQDGKITRQEF------IDGILASKFPTTKLEMTAVADI------FDRDGDGYI 80 Query: 165 TLEEFC 170 EF Sbjct: 81 DYYEFV 86 Score = 33.5 bits (75), Expect = 0.052, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 18/30 (60%) Query: 148 RVNKIFNMMDKNKDGQLTLEEFCEGSKRDP 177 RV F +DK++DG++T +EF +G Sbjct: 28 RVMDFFRRIDKDQDGKITRQEFIDGILASK 57 >5PAL-A nrPDB Length = 109 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 39/96 (40%), Gaps = 11/96 (11%) Query: 78 GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 G D+K F + + +G+ + ++ F++ D D +G I +E+ ++ Sbjct: 22 GTFDYKRFFHLVGL--KGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGR---- 75 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 D + + D + DG++ +EF + Sbjct: 76 -----DLNDTETKALLAAGDSDHDGKIGADEFAKMV 106 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 47 EFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL---SVTSRGELNDKLIW 103 ++++ + G A + VF + D D++G+I+ +E L S R + + Sbjct: 25 DYKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKA 84 Query: 104 AFQLYDLDNNGLISYDEMLRIV 125 D D++G I DE ++V Sbjct: 85 LLAAGDSDHDGKIGADEFAKMV 106 Score = 35.0 bits (79), Expect = 0.021, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 32/77 (41%), Gaps = 3/77 (3%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD--PSAFAEYVFNVFD 73 LV ++++ ++ KD SG + + E + + K F G + + D Sbjct: 32 LVGLKGKTDAQVKEVFEILDKD-QSGFIEEEELKGVLKGFSAHGRDLNDTETKALLAAGD 90 Query: 74 ADKNGYIDFKEFICALS 90 +D +G I EF ++ Sbjct: 91 SDHDGKIGADEFAKMVA 107 >5H53-B nrPDB Length = 146 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 16/147 (10%), Positives = 54/147 (36%), Gaps = 18/147 (12%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 +E ++ + ++ G ++K + + + + + + + +G I+F Sbjct: 5 QEFKEAFTVIDQN-RDGIIDKEDLRDTFAAMGRLNVKNEELDAMM----KEASGPINFTV 59 Query: 85 FICALSVTSRGELNDKLIW-AFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDED 143 F+ +G + +I AF++ D + G I + ++ + + + Sbjct: 60 FLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELL------------ITQCDR 107 Query: 144 TPEKRVNKIFNMMDKNKDGQLTLEEFC 170 ++ + ++ + G + + C Sbjct: 108 FSQEEIKNMWAAFSPDVGGNVDYKNIC 134 Score = 27.7 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 41/108 (37%), Gaps = 15/108 (13%) Query: 64 FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 + F V D +++G ID ++ + R + ++ + A + +G I++ L Sbjct: 6 EFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDA---MMKEASGPINFTVFLT 62 Query: 124 IVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + K PE + F ++D G + ++F E Sbjct: 63 MFGEKLKGAD-----------PEDVITGAFKVLDPEGKGTI-KKQFLE 98 >5H53-C nrPDB Length = 153 Score = 46.2 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 20/156 (12%), Positives = 60/156 (38%), Gaps = 18/156 (11%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 ++ + E ++ + + + S + S+ + + + + + N + + N Sbjct: 6 SKEQQDEFKEAFLLYDRTGDS-KITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAK 64 Query: 80 -IDFKEFICALSVTSRGE---LNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 I+F++F+ L S + + + +++D + NG + E+ ++ + Sbjct: 65 KIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG------ 118 Query: 136 VKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 E E+ V + ++ +G + E F + Sbjct: 119 ------EKMKEEEVEALMAGQ-EDSNGCINYEAFVK 147 Score = 31.5 bits (70), Expect = 0.21, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 11/87 (12%) Query: 98 NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIY-----KMVGSMVKLPEDEDTPEKRVN-- 150 D+ AF LYD + I+ ++ ++ A+ V ++ P +E+ K++ Sbjct: 10 QDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFE 69 Query: 151 ---KIFNMMDKNKDGQLTLEEFCEGSK 174 + + NKD Q T E+F EG + Sbjct: 70 QFLPMLQAISNNKD-QGTYEDFVEGLR 95 >5E1J-A nrPDB Length = 741 Score = 46.2 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 39/95 (41%), Gaps = 7/95 (7%) Query: 81 DFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPE 140 FKE + L AF L D D NG I ++ +++ + + LP+ Sbjct: 307 SFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQ----CIKLFEQLTNYRTLPK 362 Query: 141 DEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 ++ IF+ +D +D ++ +EF + + Sbjct: 363 ---ISKEEFGLIFDELDDTRDFKINKDEFADLCQA 394 Score = 33.1 bits (74), Expect = 0.078, Method: Composition-based stats. Identities = 12/104 (11%), Positives = 41/104 (39%), Gaps = 5/104 (4%) Query: 9 SQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD----PSAF 64 + + + + ++ L++ + D +G ++K++ K+++Q + Sbjct: 309 KEQLAKQVSGMDQMKRRMLEKAFGLIDSD-KNGEIDKNQCIKLFEQLTNYRTLPKISKEE 367 Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLY 108 +F+ D ++ I+ EF + +++ F+ + Sbjct: 368 FGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHF 411 >3SIA-A nrPDB Length = 220 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 43/120 (35%), Gaps = 17/120 (14%) Query: 25 KELQQWYKGFF--KDCPSGHLNKSEFQKIYKQF-FPFGDPSAFAEYVFNVFDADKNGYID 81 + + Y+ F SG L +E QF A + +FD D NG+I Sbjct: 48 DQYTRIYQWFMGVDRDRSGTLEINELM--MGQFPGGIRLSPQTALRMMRIFDTDFNGHIS 105 Query: 82 FKEFICALSVTSRGELNDKLIWAFQLYDLDN---NGLISYDEMLRIVDAIYKMVGSMVKL 138 F EF+ + A+ L+ ++ +G + E+L + + + L Sbjct: 106 FYEFMAMYKF---------MELAYNLFVMNARARSGTLEPHEILPALQQLGFYINQRTSL 156 Score = 34.6 bits (78), Expect = 0.026, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 25/70 (35%), Gaps = 12/70 (17%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F D D +G + +E+ M+G + ++ + D + +G + Sbjct: 57 FMGVDRDRSGTLEINEL---------MMGQFPGGIR---LSPQTALRMMRIFDTDFNGHI 104 Query: 165 TLEEFCEGSK 174 + EF K Sbjct: 105 SFYEFMAMYK 114 >2NCO-A nrPDB Length = 102 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 5/75 (6%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 F+ YD D +G + DE+ ++ Y +G P ED V M D N D Sbjct: 18 RRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKED-----VKIWLQMADTNSD 72 Query: 162 GQLTLEEFCEGSKRD 176 G ++LEE+ + + Sbjct: 73 GSVSLEEYEDLIIKS 87 Score = 31.1 bits (69), Expect = 0.29, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Query: 63 AFAEYVFNVFDADKNGYIDFKEFICA-------LSVTSRGELNDKLIWAFQLYDLDNNGL 115 A +F +D D +G + E + +++ + + Q+ D +++G Sbjct: 15 DVARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGS 74 Query: 116 ISYDEMLRIVDAIYKMVG 133 +S +E ++ + G Sbjct: 75 VSLEEYEDLIIKSLQKAG 92 Score = 28.4 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 25/68 (36%), Gaps = 7/68 (10%) Query: 28 QQWYKGFFKDCPSGHLNKSEFQKIYK------QFFPFGDPSAFAEYVFNVFDADKNGYID 81 ++ +K + KD SG L E + K F + + D + +G + Sbjct: 18 RRLFKRYDKD-GSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVS 76 Query: 82 FKEFICAL 89 +E+ + Sbjct: 77 LEEYEDLI 84 >1N2D-A nrPDB Length = 148 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 23/158 (14%), Positives = 61/158 (38%), Gaps = 27/158 (17%) Query: 28 QQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN---------- 77 + + F K G + K + + + + + N + ++ Sbjct: 7 KDIFTLFDKKGQ-GAIAKDSLGDYLRAI-GYNPTNQLVQDIINADSSLRDASSLTLDQIT 64 Query: 78 GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 G I+ E L T++ + D + AFQ++D ++ G +S ++ ++ + Sbjct: 65 GLIEVNE--KELDATTKAKTEDFVK-AFQVFDKESTGKVSVGDLRYMLTGLG-------- 113 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E + V+++ ++ + +G++ ++F E R Sbjct: 114 ----EKLTDAEVDELLKGVEVDSNGEIDYKKFIEDVLR 147 >4OKH-A nrPDB Length = 189 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 29/178 (16%), Positives = 65/178 (36%), Gaps = 34/178 (19%) Query: 22 FDKKELQQWYKGFFKDCPSGHLNKSEFQKIY-------KQFFPFGDPSAFAEYVFNVFDA 74 ++++ + +K + E +K+ K G + + D Sbjct: 9 EEQQQFRNIFKQIA--GDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDT 66 Query: 75 DKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGS 134 D +G ++ +EF + ++ + K+ F+ YD D +G I+ EM V+ + + Sbjct: 67 DGSGKLNLQEF---HHLWNKIKAWQKI---FKHYDTDQSGTINSYEMRNAVNDAGFHLNN 120 Query: 135 MVKLPEDEDTPEKRVN-----------------KIFNMMDKNKDGQLTLE--EFCEGS 173 + +K +N + F+ DK+ DG + L E+ + + Sbjct: 121 QLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLT 178 Score = 30.4 bits (67), Expect = 0.52, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 28/72 (38%), Gaps = 4/72 (5%) Query: 116 ISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 I DE+ ++++ + + K + + + +MD + G+L L+EF + Sbjct: 28 ICADELKKVLNTVV----NKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNK 83 Query: 176 DPTIVSALSLYD 187 YD Sbjct: 84 IKAWQKIFKHYD 95 >5B7X-A nrPDB Length = 156 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 17/142 (11%), Positives = 46/142 (32%), Gaps = 16/142 (11%) Query: 34 FFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV-- 91 F+ G ++ + + + F + ++F + Sbjct: 21 FYDRDYDGKIDVKQLGTLIRSL-GCAPTEDEVNSYIKEFAIEGE-TFQIEQFELIMEREQ 78 Query: 92 TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNK 151 + KL AF+++D D +G I ++ + + + ++ V K Sbjct: 79 SKPDTREIKLRKAFEVFDQDKDGKIKASDLAHNLTTVGDKM------------TKEEVEK 126 Query: 152 IFNMMDKNKDGQLTLEEFCEGS 173 +F+++ + + L F + Sbjct: 127 VFSILGITMESDIDLATFLKLV 148 Score = 32.7 bits (73), Expect = 0.096, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 39/101 (38%), Gaps = 25/101 (24%) Query: 89 LSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIY-----KMVGSMVKLPEDE- 142 + + + K+ F YD D +G I ++ ++ ++ V S +K E Sbjct: 3 MEIEAPNANTQKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAIEG 62 Query: 143 -------------------DTPEKRVNKIFNMMDKNKDGQL 164 DT E ++ K F + D++KDG++ Sbjct: 63 ETFQIEQFELIMEREQSKPDTREIKLRKAFEVFDQDKDGKI 103 >2M7M-A nrPDB Length = 66 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 28/64 (43%) Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 AE +F D + +G + ++E +S + L F+ D D NG I +E + Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKF 61 Query: 125 VDAI 128 +I Sbjct: 62 YGSI 65 Score = 33.8 bits (76), Expect = 0.044, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 12/71 (16%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 F+ D++ +G +SY+E+ V + E+ + IF +D + + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN------------EQLLQLIFKSIDADGN 50 Query: 162 GQLTLEEFCEG 172 G++ EF + Sbjct: 51 GEIDQNEFAKF 61 Score = 28.8 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 18/51 (35%), Gaps = 1/51 (1%) Query: 36 KDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFI 86 G ++ E + + + +F DAD NG ID EF Sbjct: 10 DVNGDGAVSYEEVKAFVSKKRAI-KNEQLLQLIFKSIDADGNGEIDQNEFA 59 Score = 28.4 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 13/30 (43%) Query: 150 NKIFNMMDKNKDGQLTLEEFCEGSKRDPTI 179 +F +D N DG ++ EE + I Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAI 32 >1IJ5-A nrPDB Length = 323 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 24/140 (17%), Positives = 62/140 (44%), Gaps = 20/140 (14%) Query: 31 YKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALS 90 ++ + +G L++ EF++ + + D + + +F D D++ + F E++ Sbjct: 194 FRKIDTN-SNGTLSRKEFREHFVRLG--FDKKSVQDALFRYADEDESDDVGFSEYV---- 246 Query: 91 VTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVN 150 L ++++AF D D +G +S +E+ ++++ + + K Sbjct: 247 HLGLCLLVLRILYAFA--DFDKSGQLSKEEVQKVLEDAHIPESARKKFEHQ--------- 295 Query: 151 KIFNMMDKNKDGQLTLEEFC 170 F+++D + L+ +EF Sbjct: 296 --FSVVDVDDSKSLSYQEFV 313 Score = 33.8 bits (76), Expect = 0.047, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 27/60 (45%) Query: 27 LQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFI 86 + + F SG L+K E QK+ + E+ F+V D D + + ++EF+ Sbjct: 254 VLRILYAFADFDKSGQLSKEEVQKVLEDAHIPESARKKFEHQFSVVDVDDSKSLSYQEFV 313 Score = 33.1 bits (74), Expect = 0.076, Method: Composition-based stats. Identities = 15/134 (11%), Positives = 45/134 (33%), Gaps = 20/134 (14%) Query: 38 CPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGEL 97 SG + + +++ ++ + +F + + D G + + + + + Sbjct: 134 SGSGKFSFQDLKQVLAKYADTIPEGPL-KKLFVMVENDTKGRMSYITLVAVANDLAALVA 192 Query: 98 NDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMD 157 + F+ D ++NG +S E + S+ + +F D Sbjct: 193 D------FRKIDTNSNGTLSRKEFREHFVRLGFDKKSVQ-------------DALFRYAD 233 Query: 158 KNKDGQLTLEEFCE 171 +++ + E+ Sbjct: 234 EDESDDVGFSEYVH 247 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 28/124 (22%), Positives = 48/124 (38%), Gaps = 8/124 (6%) Query: 3 KSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPS 62 S LS+ + ++ FDKK +Q + + S + SE+ + Sbjct: 200 NSNGTLSRKEFREHFVRLGFDKKSVQDALFRYADEDESDDVGFSEYVHLGLCLLVLRILY 259 Query: 63 AFAEYVFNVFDADKNGYIDFKEFICALS-VTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 AFA D DK+G + +E L K F + D+D++ +SY E Sbjct: 260 AFA-------DFDKSGQLSKEEVQKVLEDAHIPESARKKFEHQFSVVDVDDSKSLSYQEF 312 Query: 122 LRIV 125 + +V Sbjct: 313 VMLV 316 >3DTP-E nrPDB Length = 196 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 23/157 (14%), Positives = 59/157 (37%), Gaps = 20/157 (12%) Query: 20 TRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY 79 T+ +E ++ ++ +D G ++K++ + + V A+ G Sbjct: 52 TQHQVQEFKEAFQLIDQD-KDGFISKNDIRATFDSLGRLCTEQELDSMV-----AEAPGP 105 Query: 80 IDFKEFICALSVTSRGELNDKLI-WAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKL 138 I+F F+ G + +I AF L+D + +G + + R + Sbjct: 106 INFTMFLTIFGDRIAGTDEEDVIVNAFNLFD-EGDGKCKEETLKRSLTTWG--------- 155 Query: 139 PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 E + V++ + + +G + +++F + + Sbjct: 156 ---EKFSQDEVDQALSEAPIDGNGLIDIKKFAQILTK 189 Score = 33.8 bits (76), Expect = 0.041, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 37/94 (39%), Gaps = 1/94 (1%) Query: 41 GHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDK 100 G +N + F I+ D FN+FD + +G + +L+ D+ Sbjct: 104 GPINFTMFLTIFGDRIAGTDEEDVIVNAFNLFD-EGDGKCKEETLKRSLTTWGEKFSQDE 162 Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGS 134 + A +D NGLI + +I+ K G+ Sbjct: 163 VDQALSEAPIDGNGLIDIKKFAQILTKGAKEEGA 196 Score = 32.7 bits (73), Expect = 0.093, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 38/96 (39%), Gaps = 23/96 (23%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 + AFQL D D +G IS +++ D++ ++ E+ ++ + Sbjct: 57 QEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLC------------TEQELDSMVAEA-- 102 Query: 159 NKDGQLTLEEF-------CEGSKRDPTIVSALSLYD 187 G + F G+ + IV+A +L+D Sbjct: 103 --PGPINFTMFLTIFGDRIAGTDEEDVIVNAFNLFD 136 >2KYF-A nrPDB Length = 108 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 28/83 (33%), Gaps = 9/83 (10%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 + + +L F++ D D +G I DE+ + + Sbjct: 35 MSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTAS---------ETKTF 85 Query: 153 FNMMDKNKDGQLTLEEFCEGSKR 175 D + DG++ EEF E + Sbjct: 86 LAAADHDGDGKIGAEEFQEMVQS 108 Score = 35.4 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 28/72 (38%), Gaps = 3/72 (4%) Query: 59 GDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRG---ELNDKLIWAFQLYDLDNNGL 115 S+ + +F + D D++G+I+ E L G + D D +G Sbjct: 37 KKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFLAAADHDGDGK 96 Query: 116 ISYDEMLRIVDA 127 I +E +V + Sbjct: 97 IGAEEFQEMVQS 108 >1GJY-A nrPDB Length = 167 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 20/150 (13%), Positives = 48/150 (32%), Gaps = 24/150 (16%) Query: 38 CPSGHLNKSEFQKIYKQFFPFGDPSAFA----EYVFNVFDADKNGYIDFKEFICALSVTS 93 G ++ E Q+ Q G F + ++ D D +G + F EF +V + Sbjct: 13 GQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLN 72 Query: 94 RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIF 153 + F +D D +G + E+ + + + + + Sbjct: 73 GWRQH------FISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYSTS------ 120 Query: 154 NMMDKNKDGQLTLEEFCEGSKRDPTIVSAL 183 G++T +++ + + + Sbjct: 121 --------GKITFDDYIACCVKLRALTDSF 142 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 38/95 (40%), Gaps = 9/95 (9%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEF 85 E + SG + +EF++++ + F FD+D++G +D +E Sbjct: 42 ETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQH-------FISFDSDRSGTVDPQEL 94 Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 AL+ + + Y +G I++D+ Sbjct: 95 QKALTTMGFRLNPQTVNSIAKRYST--SGKITFDD 127 >3I5H-B nrPDB Length = 153 Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 21/138 (15%), Positives = 49/138 (35%), Gaps = 7/138 (5%) Query: 11 DQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFN 70 ++ V+ ++ +EL++ + +D G + + + ++ N Sbjct: 2 EEAPRRVKLSQRQMQELKEAFTMIDQD-RDGFIGMEDLKDMFSSLGRVPPDDE-----LN 55 Query: 71 VFDADKNGYIDFKEFICALSVTSRGELNDK-LIWAFQLYDLDNNGLISYDEMLRIVDAIY 129 + G ++F F+ G + L AF ++D D G I D + +++ + Sbjct: 56 AMLKECPGQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMG 115 Query: 130 KMVGSMVKLPEDEDTPEK 147 +D P K Sbjct: 116 DNFSKEEIKNVWKDAPLK 133 >2KQY-A nrPDB Length = 108 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 35/98 (35%), Gaps = 11/98 (11%) Query: 78 GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 ++K F + ++S+ D++ F + D D +G I +E+ + + Sbjct: 22 DSFNYKSFFSTVGLSSKTP--DQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLT- 78 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 D + DG++ +EEF K Sbjct: 79 --------SAETKAFLAAGDTDGDGKIGVEEFQSLVKA 108 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 35/83 (42%), Gaps = 3/83 (3%) Query: 48 FQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE---FICALSVTSRGELNDKLIWA 104 ++ + + VF + D DK+G+I+ +E F+ S ++R + + Sbjct: 26 YKSFFSTVGLSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAF 85 Query: 105 FQLYDLDNNGLISYDEMLRIVDA 127 D D +G I +E +V A Sbjct: 86 LAAGDTDGDGKIGVEEFQSLVKA 108 Score = 34.2 bits (77), Expect = 0.035, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 28/77 (36%), Gaps = 3/77 (3%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD--PSAFAEYVFNVFDA 74 V + ++++ + G SG + + E Q K F SA + D Sbjct: 33 VGLSSKTPDQIKKVF-GILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAFLAAGDT 91 Query: 75 DKNGYIDFKEFICALSV 91 D +G I +EF + Sbjct: 92 DGDGKIGVEEFQSLVKA 108 >4L9M-A nrPDB Length = 559 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 9/57 (15%) Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 + VF +D D++GYI +EF + ++F + D D GLIS DE+ Sbjct: 427 VDSVFKNYDHDQDGYISQEEFEKIAASFP---------FSFCVMDKDREGLISRDEI 474 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 34/85 (40%), Gaps = 21/85 (24%) Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNK 160 + F+ YD D +G IS +E +I + F +MDK++ Sbjct: 427 VDSVFKNYDHDQDGYISQEEFEKIAASFPFS---------------------FCVMDKDR 465 Query: 161 DGQLTLEEFCEGSKRDPTIVSALSL 185 +G ++ +E R +I S L L Sbjct: 466 EGLISRDEITAYFMRASSIYSKLGL 490 Score = 34.6 bits (78), Expect = 0.023, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 22/54 (40%) Query: 124 IVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDP 177 +V V ++ V+ +F D ++DG ++ EEF + + P Sbjct: 402 VVVDWASGVSPKPDPKTISKHVQRMVDSVFKNYDHDQDGYISQEEFEKIAASFP 455 >3I5I-C nrPDB Length = 159 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 27/167 (16%), Positives = 61/167 (36%), Gaps = 20/167 (11%) Query: 17 VRSTRFDKKELQQWYKGFFK-DCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDAD 75 + T+ + +E+++ + F D G ++ ++ + + + ++ Sbjct: 1 SQLTKDEIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQH--GGTKKM 58 Query: 76 KNGYIDFKEFICA---LSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 +E + +S G D+ + AF+ +D + GLIS E+ ++ + Sbjct: 59 GEKAYKLEEILPIYEEMSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKMLG--- 115 Query: 133 GSMVKLPEDEDTPEKRVNKIFNMMDK--NKDGQLTLEEFCEGSKRDP 177 E E + N IF D + DG + E+ + P Sbjct: 116 ---------ERITEDQCNDIFTFCDIREDIDGNIKYEDLMKKVMAGP 153 >2MA2-A nrPDB Length = 81 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 24/60 (40%), Gaps = 7/60 (11%) Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 E VF FD D +G+I +EF AF D + +G IS +EM Sbjct: 12 EKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYL-------SAFGDLDQNQDGCISREEM 64 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 32/86 (37%), Gaps = 19/86 (22%) Query: 97 LNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMM 156 + + F+ +D+D +G IS +E I + F + Sbjct: 11 IEKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLSA-------------------FGDL 51 Query: 157 DKNKDGQLTLEEFCEGSKRDPTIVSA 182 D+N+DG ++ EE R +++ Sbjct: 52 DQNQDGCISREEMVSYFLRSSSVLGG 77 Score = 29.6 bits (65), Expect = 0.92, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 31/64 (48%), Gaps = 9/64 (14%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 +K ++ ++ F D GH+++ EFQ I + FP+ F D +++G I + Sbjct: 12 EKMVESVFRNFDVD-GDGHISQEEFQ-IIRGNFPYLSA-------FGDLDQNQDGCISRE 62 Query: 84 EFIC 87 E + Sbjct: 63 EMVS 66 >6EAZ-A nrPDB Length = 379 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 45/122 (36%), Gaps = 9/122 (7%) Query: 73 DADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D G I + E++ L++ ++ AF++ D+D N +I E +++ I K Sbjct: 95 DLGDKGVISYTEYLFLLTILTKPHSG--FHVAFKMLDVDGNEMIERKEFVKLQKIISKQD 152 Query: 133 GSMVKLPEDEDTPEKRVNK-------IFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 G + + + V + K + +L +EF + T V + Sbjct: 153 GFKTVKTNETEYQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFMENLQTEVQEMEF 212 Query: 186 YD 187 Sbjct: 213 LQ 214 Score = 33.8 bits (76), Expect = 0.048, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Query: 84 EFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 EF A+ V T + ++ L F+++DLD + +S+ E L ++ Sbjct: 293 EFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKN 337 Score = 29.6 bits (65), Expect = 0.75, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 35/90 (38%), Gaps = 7/90 (7%) Query: 7 KLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAE 66 KL++ ++D+ + + F G ++ +E+ + P + Sbjct: 70 KLAKKDIEDV--LSGIQTARCGSTF--FRDLGDKGVISYTEYLFLLTIL---TKPHSGFH 122 Query: 67 YVFNVFDADKNGYIDFKEFICALSVTSRGE 96 F + D D N I+ KEF+ + S+ + Sbjct: 123 VAFKMLDVDGNEMIERKEFVKLQKIISKQD 152 Score = 29.6 bits (65), Expect = 0.93, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 18/47 (38%) Query: 47 EFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTS 93 EF++ K + VF +FD D + + EF+ L Sbjct: 293 EFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKNRM 339 >1JUO-A nrPDB Length = 198 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 37/95 (38%), Gaps = 9/95 (9%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEF 85 E + SG + +EF++++ + F FD D++G +D +E Sbjct: 73 ETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQH-------FISFDTDRSGTVDPQEL 125 Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 AL+ + + Y NG I++D+ Sbjct: 126 QKALTTMGFRLSPQAVNSIAKRYST--NGKITFDD 158 Score = 31.1 bits (69), Expect = 0.32, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 22/60 (36%), Gaps = 7/60 (11%) Query: 112 NNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 +G I DE+ R + G + + +M+D++ G + EF E Sbjct: 45 QDGQIDADELQRCLTQSGIAGGYKPFNL-------ETCRLMVSMLDRDMSGTMGFNEFKE 97 Score = 26.1 bits (56), Expect = 8.7, Method: Composition-based stats. Identities = 13/101 (12%), Positives = 31/101 (30%), Gaps = 23/101 (22%) Query: 77 NGYIDFKEFICALSVTS-----RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 +G ID E L+ + + + + D D +G + ++E + + Sbjct: 46 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNG- 104 Query: 132 VGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEG 172 + F D ++ G + +E + Sbjct: 105 -----------------WRQHFISFDTDRSGTVDPQELQKA 128 >1QX2-A nrPDB Length = 76 Score = 43.1 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 33/72 (45%), Gaps = 2/72 (2%) Query: 25 KELQQWYKGFF-KDCPSGHLNKSEFQKIYKQFFP-FGDPSAFAEYVFNVFDADKNGYIDF 82 +E++ ++ F K+ ++K E + + + P + + + D + +G + F Sbjct: 5 EEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGEVSF 64 Query: 83 KEFICALSVTSR 94 +EF+ + S+ Sbjct: 65 EEFLVMMKKISQ 76 Score = 42.7 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 39/85 (45%), Gaps = 18/85 (21%) Query: 96 ELNDKLIWAFQLY-----DLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVN 150 + +++ AF+++ D + IS +E+ ++ + + + ++ Sbjct: 2 KSPEEIKGAFEVFAAKEGDPNQ---ISKEELKLVMQTLGPSLLKGMS----------TLD 48 Query: 151 KIFNMMDKNKDGQLTLEEFCEGSKR 175 ++ +DKN DG+++ EEF K+ Sbjct: 49 EMIEEVDKNGDGEVSFEEFLVMMKK 73 Score = 28.4 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Query: 60 DPSAFAEYVFNVFDADKNG--YIDFKEFICALSVTSRGELN--DKLIWAFQLYDLDNNGL 115 + F VF A + I +E + L L + D + +G Sbjct: 2 KSPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGE 61 Query: 116 ISYDEMLRIVDAIYK 130 +S++E L ++ I + Sbjct: 62 VSFEEFLVMMKKISQ 76 >2K7B-A nrPDB Length = 76 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 31/75 (41%), Gaps = 12/75 (16%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 ++L AF+ +D D +G I+ ++ + + M E + ++ ++ Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMP------------TEMELIELSQQINM 57 Query: 159 NKDGQLTLEEFCEGS 173 N G + ++F E Sbjct: 58 NLGGHVDFDDFVELM 72 Score = 34.2 bits (77), Expect = 0.034, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 29/69 (42%) Query: 58 FGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLIS 117 + F FD DK+GYI+ ++ + +LI Q +++ G + Sbjct: 5 RPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVD 64 Query: 118 YDEMLRIVD 126 +D+ + ++ Sbjct: 65 FDDFVELMG 73 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 30/68 (44%), Gaps = 2/68 (2%) Query: 22 FDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYID 81 + +EL++ ++ F KD G++N + + E + + + G++D Sbjct: 7 EEIEELREAFREFDKD-KDGYINCRDLGNCMRTMGYMPTEMELIE-LSQQINMNLGGHVD 64 Query: 82 FKEFICAL 89 F +F+ + Sbjct: 65 FDDFVELM 72 >5MRA-A nrPDB Length = 167 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 37/95 (38%), Gaps = 9/95 (9%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEF 85 E + SG + +EF++++ + F FD D++G +D +E Sbjct: 42 ETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQH-------FISFDTDRSGTVDPQEL 94 Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 AL+ + + Y NG I++D+ Sbjct: 95 QKALTTMGFRLSPQAVNSIAKRYST--NGKITFDD 127 Score = 30.4 bits (67), Expect = 0.46, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 22/60 (36%), Gaps = 7/60 (11%) Query: 112 NNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 +G I DE+ R + G + + +M+D++ G + EF E Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNL-------ETCRLMVSMLDRDMSGTMGFNEFKE 66 >1RTP-1 nrPDB Length = 109 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 36/99 (36%), Gaps = 11/99 (11%) Query: 78 GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 D K+F + + + D + F + D D +G I DE+ I+ Sbjct: 22 DSFDHKKFFQMVGLKKK--SADDVKKVFHILDKDKSGFIEEDELGSILKGFS-------- 71 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRD 176 + D K + DK+ DG++ +EEF Sbjct: 72 -SDARDLSAKETKTLMAAGDKDGDGKIGVEEFSTLVAES 109 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 32/80 (40%), Gaps = 3/80 (3%) Query: 49 QKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLY 108 +K ++ + + VF++ D DK+G+I+ E L S + L Sbjct: 27 KKFFQMVGLKKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLM 86 Query: 109 ---DLDNNGLISYDEMLRIV 125 D D +G I +E +V Sbjct: 87 AAGDKDGDGKIGVEEFSTLV 106 Score = 32.7 bits (73), Expect = 0.093, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 31/78 (39%), Gaps = 3/78 (3%) Query: 15 DLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD--PSAFAEYVFNVF 72 +V + ++++ + KD SG + + E I K F + + + Sbjct: 31 QMVGLKKKSADDVKKVFHILDKD-KSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAG 89 Query: 73 DADKNGYIDFKEFICALS 90 D D +G I +EF ++ Sbjct: 90 DKDGDGKIGVEEFSTLVA 107 >4MSP-A nrPDB Length = 200 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 4/70 (5%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + +FQ DL+++ +S DE+ + ++ G++V E + V IF+ D++ Sbjct: 128 RSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVN----ESHHDALVEDIFDKEDED 183 Query: 160 KDGQLTLEEF 169 KDG ++ EF Sbjct: 184 KDGFISAREF 193 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 23/58 (39%), Gaps = 7/58 (12%) Query: 35 FKDCPSGHLNKSEFQKIYKQFF-------PFGDPSAFAEYVFNVFDADKNGYIDFKEF 85 L+K E + K+ F A E +F+ D DK+G+I +EF Sbjct: 136 MDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFISAREF 193 >2LVV-A nrPDB Length = 226 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 1/60 (1%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEF 85 EL + KD S L EF++ + +G A VFN D + +G + F EF Sbjct: 134 ELTVMFDTMDKD-GSLLLELQEFKEALPKLKEWGVDITDATTVFNEIDTNGSGVVTFDEF 192 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 46/159 (28%), Gaps = 25/159 (15%) Query: 22 FDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN---- 77 K + +K F + + Y + + V FD K+ Sbjct: 48 ESKSRRIELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNK 107 Query: 78 -------GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 ++F EF L +L F D D + L+ E + + + Sbjct: 108 VKGVGEEDLVEFLEFRLMLCYIYDIF---ELTVMFDTMDKDGSLLLELQEFKEALPKLKE 164 Query: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 + +FN +D N G +T +EF Sbjct: 165 WGVDITDATT-----------VFNEIDTNGSGVVTFDEF 192 Score = 31.5 bits (70), Expect = 0.24, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 32/85 (37%), Gaps = 2/85 (2%) Query: 88 ALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEK 147 A+ E + I F+ +D + G + + E+L I K+ LP+ Sbjct: 40 AIPRDKDAESKSRRIELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFD 99 Query: 148 RVNKIFNMMDKNKDGQLTLEEFCEG 172 + + N + G+ L EF E Sbjct: 100 KAKDLGNKV--KGVGEEDLVEFLEF 122 Score = 29.6 bits (65), Expect = 0.79, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 44/114 (38%), Gaps = 12/114 (10%) Query: 67 YVFNVFDADKNGYIDFKEFICALSVTSRGE-----LNDKLIWAFQLYDLDNNGLISYDEM 121 +F FD + G + F+E + + + L D + AF N + E Sbjct: 55 ELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGE- 113 Query: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + + + + + L D E V +F+ MDK+ L L+EF E + Sbjct: 114 ----EDLVEFLEFRLMLCYIYDIFELTV--MFDTMDKDGSLLLELQEFKEALPK 161 >4I5L-B nrPDB Length = 413 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 22/181 (12%), Positives = 61/181 (33%), Gaps = 16/181 (8%) Query: 4 SQSKLSQDQLQDLVRSTRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDP 61 L +++ + F + Y F ++ + + Sbjct: 174 QNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDL----ARHNDHALS 229 Query: 62 SAFAEYVFNVFDADK-----NGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLI 116 + + +F+ G I + +F+ L + + + F+ DLD +G + Sbjct: 230 TKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGAL 289 Query: 117 SYDEMLRIVDAIYKMVGSMVKLPEDEDTP-EKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 S E+ + Y+ + E P + + ++ +++ +G++TL++ Sbjct: 290 SMFEL----EYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLA 345 Query: 176 D 176 + Sbjct: 346 N 346 >1RK9-A nrPDB Length = 110 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 37/103 (35%), Gaps = 11/103 (10%) Query: 74 ADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVG 133 D K+F + + + D + F + D D +G I DE+ I+ Sbjct: 19 FSATDSFDHKKFFQMVGLKKK--SADDVKKVFHMLDKDKSGFIEEDELGFILKGFS---- 72 Query: 134 SMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRD 176 P+ D K + DK+ DG++ ++EF Sbjct: 73 -----PDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAES 110 Score = 34.2 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 32/80 (40%), Gaps = 3/80 (3%) Query: 49 QKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLY 108 +K ++ + + VF++ D DK+G+I+ E L S + L Sbjct: 28 KKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLM 87 Query: 109 ---DLDNNGLISYDEMLRIV 125 D D +G I DE +V Sbjct: 88 AAGDKDGDGKIGVDEFSTLV 107 Score = 33.1 bits (74), Expect = 0.082, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 31/78 (39%), Gaps = 3/78 (3%) Query: 15 DLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD--PSAFAEYVFNVF 72 +V + ++++ + KD SG + + E I K F P + + + Sbjct: 32 QMVGLKKKSADDVKKVFHMLDKD-KSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAG 90 Query: 73 DADKNGYIDFKEFICALS 90 D D +G I EF ++ Sbjct: 91 DKDGDGKIGVDEFSTLVA 108 >4NSC-A nrPDB Length = 401 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 47/103 (45%), Gaps = 7/103 (6%) Query: 78 GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR---IVDAIYKMVGS 134 G I F ++I +V S + N ++ AF+++DL+ +G + +E + I+ + M Sbjct: 127 GLISFSDYIFLTTVLSTPQRNFEI--AFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMR 184 Query: 135 MVKLPEDEDTPEKRVNKIFN--MMDKNKDGQLTLEEFCEGSKR 175 P +T + + + G+LT++ F E ++ Sbjct: 185 HRDRPTTGNTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRK 227 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 37/109 (33%), Gaps = 13/109 (11%) Query: 3 KSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPS------------GHLNKSEFQK 50 K + + + + +E++ ++ F K+ L+K Q+ Sbjct: 265 KKLTAMQRQLKKHFKEGKGLTFQEVENFF-TFLKNINDVDTALSFYHMAGASLDKVTMQQ 323 Query: 51 IYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND 99 + + + VF +FD D NG + KEF+ + L Sbjct: 324 VARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLMRGLEK 372 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 26/75 (34%), Gaps = 3/75 (4%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 ++++ F+ G ++ F P E F +FD + +G +D Sbjct: 109 EREKFADEGSIFYTLGECGLIS---FSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDM 165 Query: 83 KEFICALSVTSRGEL 97 +EF S+ Sbjct: 166 EEFEQVQSIIRSQTS 180 Score = 28.4 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 9/22 (40%), Positives = 13/22 (59%) Query: 105 FQLYDLDNNGLISYDEMLRIVD 126 F L+D D NG +S E + I+ Sbjct: 342 FALFDCDGNGELSNKEFVSIMK 363 Score = 27.7 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 13/94 (13%), Positives = 35/94 (37%), Gaps = 5/94 (5%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVG--SMVKLPEDEDTPEKRVN 150 +G ++ F + + N + + + A V + + + + + Sbjct: 281 GKGLTFQEVENFF-TFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCD 339 Query: 151 KIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALS 184 +F + D + +G+L+ +EF K ++ L Sbjct: 340 VVFALFDCDGNGELSNKEFVSIMK--QRLMRGLE 371 >3JBH-C nrPDB Length = 156 Score = 41.2 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 20/142 (14%), Positives = 47/142 (33%), Gaps = 17/142 (11%) Query: 39 PSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGE-- 96 G ++ + + + P+ D + +EF+ S + + Sbjct: 23 GEGKIDARDLGDLLRSL--DCKPTLAMVKKNGGSDKRGEKKLTLEEFLPIFSQIKKEKEV 80 Query: 97 -LNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM 155 + + ++YD NG + E+ ++ ++ E + +I + Sbjct: 81 GTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLG------------ERLTDIECEEIMRV 128 Query: 156 MDKNKDGQLTLEEFCEGSKRDP 177 D++ DG L E F + P Sbjct: 129 CDEDDDGFLKYEPFVKTIIAGP 150 >3PAT-A nrPDB Length = 110 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 42/106 (39%), Gaps = 12/106 (11%) Query: 65 AEYVFNVFDA-DKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 A+ + DA G + K+F + + + + + F+ D D +G I +E+ Sbjct: 9 ADDIKKALDAVKAEGSFNHKKFFALVGL--KAMSANDVKKVFKAIDADASGFIEEEELKF 66 Query: 124 IVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 ++ + + D + DK+ DG++ ++EF Sbjct: 67 VLKSFAA---------DGRDLTDAETKAFLKAADKDGDGKIGIDEF 103 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 32/80 (40%), Gaps = 3/80 (3%) Query: 49 QKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL---SVTSRGELNDKLIWAF 105 +K + + + VF DAD +G+I+ +E L + R + + Sbjct: 28 KKFFALVGLKAMSANDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFL 87 Query: 106 QLYDLDNNGLISYDEMLRIV 125 + D D +G I DE +V Sbjct: 88 KAADKDGDGKIGIDEFETLV 107 Score = 30.0 bits (66), Expect = 0.61, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 29/77 (37%), Gaps = 3/77 (3%) Query: 16 LVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD--PSAFAEYVFNVFD 73 LV ++++ +K D SG + + E + + K F G A + D Sbjct: 33 LVGLKAMSANDVKKVFKAIDADA-SGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAAD 91 Query: 74 ADKNGYIDFKEFICALS 90 D +G I EF + Sbjct: 92 KDGDGKIGIDEFETLVH 108 >1F4Q-A nrPDB Length = 165 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 36/106 (33%), Gaps = 10/106 (9%) Query: 38 CPSGHLNKSEFQKIYKQFFPFGDPSAFAEY----VFNVFDADKNGYIDFKEFICALSVTS 93 G ++ E Q+ Q G S F+ + + D D G + F F + + Sbjct: 11 GQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALN 70 Query: 94 RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLP 139 + N F D D +G + + E+ + + + + Sbjct: 71 AWKEN------FMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTT 110 Score = 34.2 bits (77), Expect = 0.035, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 33/95 (34%), Gaps = 9/95 (9%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEF 85 E + +G + + F++++ + + F D D +G ++ E Sbjct: 40 ETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKEN-------FMTVDQDGSGTVEHHEL 92 Query: 86 ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 A+ + L + Y NG I +D+ Sbjct: 93 RQAIGLMGYRLSPQTLTTIVKRY--SKNGRIFFDD 125 >1TIZ-A nrPDB Length = 67 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 28/57 (49%) Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 A+ VF FD +K+G + EF S + ++ F+ D+D NG ++ DE Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEF 59 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 30/74 (40%), Gaps = 12/74 (16%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 F+ +D + +G +S DE + A ++ + K F +D + + Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYF------------TQEDIVKFFEEIDVDGN 51 Query: 162 GQLTLEEFCEGSKR 175 G+L +EF ++ Sbjct: 52 GELNADEFTSCIEK 65 >1A75-A nrPDB Length = 108 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 32/98 (32%), Gaps = 11/98 (11%) Query: 78 GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 +K F ++ + D + AF D D +G I DE+ + ++ Sbjct: 22 DSFSYKAFFAKCGLSGK--SADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALT- 78 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + D + DG + +EE+ K Sbjct: 79 --------DAETKAFLKAGDSDGDGAIGVEEWVALVKA 108 Score = 35.0 bits (79), Expect = 0.023, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 35/83 (42%), Gaps = 3/83 (3%) Query: 48 FQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE---FICALSVTSRGELNDKLIWA 104 ++ + + G + + F D DK+G+I+ E F+ +R + + Sbjct: 26 YKAFFAKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAF 85 Query: 105 FQLYDLDNNGLISYDEMLRIVDA 127 + D D +G I +E + +V A Sbjct: 86 LKAGDSDGDGAIGVEEWVALVKA 108 Score = 31.5 bits (70), Expect = 0.23, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 28/76 (36%), Gaps = 3/76 (3%) Query: 18 RSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP--SAFAEYVFNVFDAD 75 + ++++ + F SG + + E + + F A + D+D Sbjct: 34 GLSGKSADDIKKAF-VFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAFLKAGDSD 92 Query: 76 KNGYIDFKEFICALSV 91 +G I +E++ + Sbjct: 93 GDGAIGVEEWVALVKA 108 >6FSA-D nrPDB Length = 199 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 20/157 (12%), Positives = 53/157 (33%), Gaps = 18/157 (11%) Query: 20 TRFDKKELQQWYKGFFKDCP-SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 T +E ++ + F + + + + + + + + N Sbjct: 51 TPEQIEEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNS 110 Query: 79 YI-DFKEFICALSVTSRGE---LNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGS 134 + DF F+ L S+ + + + +++D + NG + E+ ++ + Sbjct: 111 KMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG----- 165 Query: 135 MVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 E E V K+ ++ +G + E F + Sbjct: 166 -------EKLTEDEVEKLMAG-QEDSNGCINYEAFVK 194 >3TZ1-A nrPDB Length = 74 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 28/78 (35%), Gaps = 12/78 (15%) Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 +L AF++ D + G+I D + I+ ++ + E + + Sbjct: 1 MEDLDERELKEAFRVLDKEKKGVIKVDVLRWILKSLGDEL------------TEDEIENM 48 Query: 153 FNMMDKNKDGQLTLEEFC 170 D + G + EEF Sbjct: 49 IAETDTDGSGTVDYEEFK 66 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 23/66 (34%) Query: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 + F V D +K G I L D++ D D +G + Y+E Sbjct: 6 ERELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEF 65 Query: 122 LRIVDA 127 ++ + Sbjct: 66 KCLMMS 71 >3J04-B nrPDB Length = 143 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 20/144 (13%), Positives = 46/144 (31%), Gaps = 45/144 (31%) Query: 64 FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLI--------------------- 102 + FN+ D +++G+ID ++ L+ + ++ L Sbjct: 8 EFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEGMMSEAPGPINFTMFLTMFGE 67 Query: 103 ------------WAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVN 150 AF +D + +G I D + ++ + ++ V+ Sbjct: 68 KLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRF------------TDEEVD 115 Query: 151 KIFNMMDKNKDGQLTLEEFCEGSK 174 +++ +K G EF K Sbjct: 116 EMYREAPIDKKGNFNYVEFTRILK 139 Score = 34.2 bits (77), Expect = 0.035, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 35/86 (40%) Query: 41 GHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDK 100 G +N + F ++ + DP F FD + +G+I L+ +++ Sbjct: 54 GPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEE 113 Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVD 126 + ++ +D G +Y E RI+ Sbjct: 114 VDEMYREAPIDKKGNFNYVEFTRILK 139 Score = 30.8 bits (68), Expect = 0.39, Method: Composition-based stats. Identities = 6/32 (18%), Positives = 17/32 (53%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 + AF + D + +G I +++ ++ ++ K Sbjct: 7 QEFKEAFNMIDQNRDGFIDKEDLHDMLASMGK 38 >4MEW-A nrPDB Length = 356 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 22/181 (12%), Positives = 61/181 (33%), Gaps = 16/181 (8%) Query: 4 SQSKLSQDQLQDLVRSTRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDP 61 L +++ + F + Y F ++ + + Sbjct: 166 QNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDL----ARHNDHALS 221 Query: 62 SAFAEYVFNVFDADK-----NGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLI 116 + + +F+ G I + +F+ L + + + F+ DLD +G + Sbjct: 222 TKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGAL 281 Query: 117 SYDEMLRIVDAIYKMVGSMVKLPEDEDTP-EKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 S E+ + Y+ + E P + + ++ +++ +G++TL++ Sbjct: 282 SMFEL----EYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLA 337 Query: 176 D 176 + Sbjct: 338 N 338 >2SAS-A nrPDB Length = 185 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 59/153 (38%), Gaps = 25/153 (16%) Query: 22 FDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYID 81 F K++++ + F G + ++F+ + ++ S DAD Sbjct: 5 FQKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLS--------DADYK---- 52 Query: 82 FKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPED 141 + + L D+ D++ + ++S++E L + + S+ LP Sbjct: 53 ----------SMQASLEDEWRDLKGRADINKDDVVSWEEYLAMWEKTIATCKSVADLPA- 101 Query: 142 EDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 + R+ +F MD + DG + LEEF K Sbjct: 102 --WCQNRIPFLFKGMDVSGDGIVDLEEFQNYCK 132 >6AGH-A nrPDB Length = 339 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 41/122 (33%), Gaps = 9/122 (7%) Query: 73 DADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D G I + E++ L++ ++ AF++ D D N +I E ++ I K Sbjct: 92 DLGDKGLISYTEYLFLLTILTKPHSG--FHVAFKMLDTDGNEMIEKREFFKLQKIISKQD 149 Query: 133 GSMVKLPEDEDTPEKRVNK-------IFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 M + E V + K +L +EF + T + + Sbjct: 150 DLMTVKTNETGYQEAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEF 209 Query: 186 YD 187 Sbjct: 210 LQ 211 Score = 34.2 bits (77), Expect = 0.033, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 26/45 (57%), Gaps = 1/45 (2%) Query: 84 EFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 EF A+ V T + N+ L F+++DLD + +S++E L ++ Sbjct: 290 EFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKN 334 Score = 30.4 bits (67), Expect = 0.44, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 20/47 (42%) Query: 47 EFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTS 93 EF++ K + + VF +FD D + + +EF+ L Sbjct: 290 EFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNRM 336 Score = 26.5 bits (57), Expect = 8.0, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 19/45 (42%) Query: 130 KMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 VK+ ++ ++ +F + D + D L+ EEF K Sbjct: 289 AEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLK 333 >5ZH6-A nrPDB Length = 107 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 28/80 (35%), Gaps = 9/80 (11%) Query: 96 ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM 155 + + L F + D D +G I DE+ + + E N Sbjct: 37 KSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATAR---------ELDETETNAFLAA 87 Query: 156 MDKNKDGQLTLEEFCEGSKR 175 D + DG++ ++EF K Sbjct: 88 GDSDHDGKIGVDEFKAMVKA 107 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Query: 67 YVFNVFDADKNGYIDFKE---FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 VF++ D D++G+I+ E F+ S T+R + D D++G I DE Sbjct: 44 KVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDSDHDGKIGVDEFKA 103 Query: 124 IVDA 127 +V A Sbjct: 104 MVKA 107 Score = 28.8 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 22/77 (28%), Gaps = 3/77 (3%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP--SAFAEYVFNVFDA 74 T L + + +D SG + E + + F D+ Sbjct: 32 SGLTNKSDANLAKVFDILDQD-RSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDS 90 Query: 75 DKNGYIDFKEFICALSV 91 D +G I EF + Sbjct: 91 DHDGKIGVDEFKAMVKA 107 >5I2L-A nrPDB Length = 120 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 46/115 (40%), Gaps = 27/115 (23%) Query: 56 FPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGL 115 G+P + + VFN Y +FKEF SR ++ D + F+ YD +G Sbjct: 3 MGSGEPQSPSRRVFNP-------YTEFKEF-------SRKQIKD-MEKMFKQYDAGRDGF 47 Query: 116 ISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 I E+ +++ + + + + +D++ D +L+ EF Sbjct: 48 IDLMELKLMMEKLGAPQTHL------------GLKNMIKEVDEDFDSKLSFREFL 90 Score = 36.5 bits (83), Expect = 0.008, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 34/94 (36%), Gaps = 3/94 (3%) Query: 9 SQDQLQDLVRSTRFDKKELQQWYKGFF--KDCPSGHLNKSEFQKIYKQFFPFGDPSAFAE 66 S+ F +K+++ K F G ++ E + + ++ + Sbjct: 12 SRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKL-GAPQTHLGLK 70 Query: 67 YVFNVFDADKNGYIDFKEFICALSVTSRGELNDK 100 + D D + + F+EF+ + GEL + Sbjct: 71 NMIKEVDEDFDSKLSFREFLLIFRKAAAGELQED 104 Score = 35.0 bits (79), Expect = 0.019, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 27/62 (43%) Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 E +F +DA ++G+ID E + + + L + D D + +S+ E L I Sbjct: 33 MEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLI 92 Query: 125 VD 126 Sbjct: 93 FR 94 >3CS1-A nrPDB Length = 219 Score = 40.0 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 31/162 (19%), Positives = 53/162 (32%), Gaps = 21/162 (12%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVF-NVFDA- 74 T K+ + +K F K+ +G L E + + ++ + FD Sbjct: 40 REKTAEAKQRRIELFKKFDKN-ETGKLCYDEVYSGCLEVLKLDEFTSRVRDITKRAFDKS 98 Query: 75 -------DKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 + G DF EF+ + +L F D N L+ +E R V Sbjct: 99 RTLGSKLENKGSEDFVEFLEFRLMLCYIYDFFELTVMFDEIDASGNMLVDEEEFKRAVPK 158 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 + + +F +DKN G +T +EF Sbjct: 159 LEAWGAKVEDPAA-----------LFKELDKNGTGSVTFDEF 189 Score = 32.7 bits (73), Expect = 0.090, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 24/62 (38%), Gaps = 2/62 (3%) Query: 34 FFKDCPSG--HLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV 91 F + SG +++ EF++ + +G +F D + G + F EF S Sbjct: 136 FDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAALFKELDKNGTGSVTFDEFAAWASA 195 Query: 92 TS 93 Sbjct: 196 VK 197 >5CPV-A nrPDB Length = 109 Score = 40.0 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 28/80 (35%), Gaps = 9/80 (11%) Query: 96 ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM 155 + D + AF + D D +G I DE+ + + + Sbjct: 39 KSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKA---------DARALTDGETKTFLKA 89 Query: 156 MDKNKDGQLTLEEFCEGSKR 175 D + DG++ ++EF K Sbjct: 90 GDSDGDGKIGVDEFTALVKA 109 Score = 35.8 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 33/82 (40%), Gaps = 3/82 (3%) Query: 49 QKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE---FICALSVTSRGELNDKLIWAF 105 + + + + + F + D DK+G+I+ E F+ +R + + Sbjct: 28 KAFFAKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFL 87 Query: 106 QLYDLDNNGLISYDEMLRIVDA 127 + D D +G I DE +V A Sbjct: 88 KAGDSDGDGKIGVDEFTALVKA 109 >1G33-A nrPDB Length = 73 Score = 40.0 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 30/81 (37%), Gaps = 9/81 (11%) Query: 96 ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM 155 + D + F + D D +G I DE+ I+ + D K + Sbjct: 2 KSADDVKKVFHILDKDKSGFIEEDELGSILKGFS---------SDARDLSAKETKTLMAA 52 Query: 156 MDKNKDGQLTLEEFCEGSKRD 176 DK+ DG++ +EEF Sbjct: 53 GDKDGDGKIGVEEFSTLVAES 73 Score = 34.6 bits (78), Expect = 0.028, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 28/69 (40%), Gaps = 3/69 (4%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLY---DLDNNGLI 116 + + VF++ D DK+G+I+ E L S + L D D +G I Sbjct: 2 KSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKI 61 Query: 117 SYDEMLRIV 125 +E +V Sbjct: 62 GVEEFSTLV 70 Score = 31.5 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 28/70 (40%), Gaps = 3/70 (4%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD--PSAFAEYVFNVFDADKNGYI 80 ++++ + KD SG + + E I K F + + + D D +G I Sbjct: 3 SADDVKKVFHILDKD-KSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKI 61 Query: 81 DFKEFICALS 90 +EF ++ Sbjct: 62 GVEEFSTLVA 71 >4PAL-A nrPDB Length = 108 Score = 40.0 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 34/93 (36%), Gaps = 11/93 (11%) Query: 83 KEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDE 142 KEF + + S+ D + AF + D D +G I DE+ + P Sbjct: 27 KEFFAKVGLASKSL--DDVKKAFYVIDQDKSGFIEEDELKLFLQNFS---------PSAR 75 Query: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + DK+ DG + ++EF K Sbjct: 76 ALTDAETKAFLADGDKDGDGMIGVDEFAAMIKA 108 Score = 34.2 bits (77), Expect = 0.032, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 35/82 (42%), Gaps = 3/82 (3%) Query: 49 QKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE---FICALSVTSRGELNDKLIWAF 105 ++ + + + F V D DK+G+I+ E F+ S ++R + + Sbjct: 27 KEFFAKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFL 86 Query: 106 QLYDLDNNGLISYDEMLRIVDA 127 D D +G+I DE ++ A Sbjct: 87 ADGDKDGDGMIGVDEFAAMIKA 108 Score = 28.8 bits (63), Expect = 1.5, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 19/58 (32%), Gaps = 2/58 (3%) Query: 36 KDCPSGHLNKSEFQKIYKQFFPFGDP--SAFAEYVFNVFDADKNGYIDFKEFICALSV 91 SG + + E + + F P A + D D +G I EF + Sbjct: 51 DQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLADGDKDGDGMIGVDEFAAMIKA 108 >1S6J-A nrPDB Length = 87 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 29/70 (41%), Gaps = 12/70 (17%) Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNK 160 L F++ D DN+G I++DE+ + + + E + + + D +K Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLKRVGSEL------------MESEIKDLMDAADIDK 72 Query: 161 DGQLTLEEFC 170 G + EF Sbjct: 73 SGTIDYGEFI 82 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 R + + L++ +K D SG + E + K+ S + + + D DK Sbjct: 15 ERLSEEEIGGLKELFKMIDTDN-SGTITFDELKDGLKRVGSELMESEIKD-LMDAADIDK 72 Query: 77 NGYIDFKEFICA 88 +G ID+ EFI A Sbjct: 73 SGTIDYGEFIAA 84 Score = 39.6 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 23/56 (41%) Query: 66 EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 + +F + D D +G I F E L + ++ D+D +G I Y E Sbjct: 26 KELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEF 81 Score = 28.1 bits (61), Expect = 2.6, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 17/27 (62%) Query: 149 VNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + ++F M+D + G +T +E +G KR Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLKR 51 >3DF0-A nrPDB Length = 714 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 19/157 (12%), Positives = 48/157 (30%), Gaps = 26/157 (16%) Query: 38 CPSGHLNKSEFQKIYKQFF-------PFGDPSAFAEYVFNVFDADKNGYIDFKEFICALS 90 ++ E Q I ++ G + + ++ D D +G + KEF + Sbjct: 543 GEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWT 602 Query: 91 VTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVN 150 K ++ D+D +G ++ EM + ++ + + + + Sbjct: 603 KI------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFAD---D 653 Query: 151 KIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYD 187 ++ + + F R + D Sbjct: 654 ELI----------IDFDNFVRCLVRLEILFKIFKQLD 680 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 35/95 (36%), Gaps = 9/95 (9%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 ++ Q+ Y+ D SG +N E +K ++ V AD IDF Sbjct: 605 QKYQKIYREIDVD-RSGTMNSYEMRKALEEAGFKLPCQL--HQVIVARFADDELIIDFDN 661 Query: 85 FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 F+ L + L F+ D +N G I D Sbjct: 662 FVRCLVRL------EILFKIFKQLDPENTGTIQLD 690 >2W4G-C nrPDB Length = 145 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 17/151 (11%), Positives = 52/151 (34%), Gaps = 18/151 (11%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY-IDFK 83 + ++ + F + + S+ I + + + + N + N I F+ Sbjct: 4 NDFKEAFLLFDR-TGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKITFE 62 Query: 84 EFICALSVTSRGELN---DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPE 140 EF+ L + + + + +++D + NG + E+ ++ + + + Sbjct: 63 EFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEEVEEL 122 Query: 141 DEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 + ++ +G + E F + Sbjct: 123 MKGQ-------------EDSNGCINYEAFVK 140 Score = 30.4 bits (67), Expect = 0.49, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 34/82 (41%), Gaps = 9/82 (10%) Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYK-----MVGSMVKLPEDEDTPEKRV--NKI-- 152 AF L+D + I+ ++ IV A+ + + ++ P E+ K++ + Sbjct: 7 KEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKITFEEFLP 66 Query: 153 FNMMDKNKDGQLTLEEFCEGSK 174 N Q T E+F EG + Sbjct: 67 MLQAAANNKDQGTFEDFVEGLR 88 >5TBY-C nrPDB Length = 195 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 20/157 (12%), Positives = 54/157 (34%), Gaps = 18/157 (11%) Query: 20 TRFDKKELQQWYKGFFKDCP-SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 T +E ++ + F + + + + + + + + N Sbjct: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNT 106 Query: 79 YI-DFKEFICALSVTSRGE---LNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGS 134 + DF+ F+ L S+ + + + +++D + NG + E+ ++ + Sbjct: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG----- 161 Query: 135 MVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 E E V K+ ++ +G + E F + Sbjct: 162 -------ERLTEDEVEKLMAG-QEDSNGCINYEAFVK 190 >1KFX-S nrPDB Length = 184 Score = 39.6 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 9/89 (10%) Query: 28 QQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFIC 87 Q YK F D SG + SE ++ + + + + +D++G +DF FI Sbjct: 91 QAIYKQFDTD-RSGTICSSELPGAFEAAGFHLNEHLY-NMIIRRY-SDESGNMDFDNFIS 147 Query: 88 ALSVTSRGELNDKLIWAFQLYDLDNNGLI 116 L D + AF+ D D G I Sbjct: 148 CLVRL------DAMFRAFKSLDKDGTGQI 170 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 28/178 (15%), Positives = 65/178 (36%), Gaps = 33/178 (18%) Query: 23 DKKELQQWYKGFFKDCPSGH-LNKSEFQKIYKQFF---PFGDPSAF----AEYVFNVFDA 74 + +E++Q+ + F + ++ +E I + P F + V D+ Sbjct: 10 ESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDS 69 Query: 75 DKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGS 134 D G + F+EF + R + ++ +D D +G I E+ +A + Sbjct: 70 DTTGKLGFEEFKYLWNNIKRWQ------AIYKQFDTDRSGTICSSELPGAFEAAGFHLNE 123 Query: 135 MVKLPEDEDTPEK--------------RVNKIFNMM---DKNKDGQL--TLEEFCEGS 173 + ++ R++ +F DK+ GQ+ ++E+ + + Sbjct: 124 HLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLT 181 >4OCI-A nrPDB Length = 146 Score = 39.6 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 62/151 (41%), Gaps = 23/151 (15%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYI---D 81 ++L++ + F D G+L +EF+ + + + SA A + N + Sbjct: 6 EDLKESFLLFDGD-GDGYLTLNEFESLVRVLGVVMETSAIAST------YNSNSKVRGMS 58 Query: 82 FKEFICALS-VTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPE 140 ++ F S + ++ D++ A + D D G I E+ RI+ I Sbjct: 59 YELFTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIG----------- 107 Query: 141 DEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 ++ +K + +F M ++ G + +++F Sbjct: 108 -DNMEQKEITDLFTFMGIDEQGVVKVDDFIN 137 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 19/36 (52%) Query: 94 RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIY 129 + N+ L +F L+D D +G ++ +E +V + Sbjct: 1 MQKHNEDLKESFLLFDGDGDGYLTLNEFESLVRVLG 36 Score = 26.9 bits (58), Expect = 6.1, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 15/28 (53%) Query: 147 KRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 + + + F + D + DG LTL EF + Sbjct: 6 EDLKESFLLFDGDGDGYLTLNEFESLVR 33 >2FCE-A nrPDB Length = 70 Score = 39.6 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 36/77 (46%), Gaps = 12/77 (15%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 + + AFQ++D ++ G +S ++ ++ + E + V+++ ++ Sbjct: 5 EDFVKAFQVFDKESTGKVSVGDLRYMLTGLG------------EKLTDAEVDELLKGVEV 52 Query: 159 NKDGQLTLEEFCEGSKR 175 + +G++ ++F E R Sbjct: 53 DSNGEIDYKKFIEDVLR 69 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 24/57 (42%) Query: 67 YVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 F VFD + G + + L+ + ++ + ++D+NG I Y + + Sbjct: 9 KAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFIE 65 Score = 26.5 bits (57), Expect = 6.3, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 29/63 (46%), Gaps = 2/63 (3%) Query: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 ++ + ++ F K+ +G ++ + + + A + + + D NG ID+K Sbjct: 4 TEDFVKAFQVFDKE-STGKVSVGDLRYMLTGL-GEKLTDAEVDELLKGVEVDSNGEIDYK 61 Query: 84 EFI 86 +FI Sbjct: 62 KFI 64 >2PMY-A nrPDB Length = 91 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 5/68 (7%) Query: 23 DKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYI 80 D +EL + F SG L + EF+ + + A AE VF DAD++G I Sbjct: 22 DGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRP---ADAEAVFQRLDADRDGAI 78 Query: 81 DFKEFICA 88 F+EF Sbjct: 79 TFQEFARG 86 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Query: 57 PFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLI 116 G+ A VF DA+++G ++ +EF + + + FQ D D +G I Sbjct: 21 GDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAE--AVFQRLDADRDGAI 78 Query: 117 SYDEMLR 123 ++ E R Sbjct: 79 TFQEFAR 85 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 26/73 (35%), Gaps = 14/73 (19%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 +L F D + +G + +E + + +F +D + Sbjct: 28 RLRSVFAACDANRSGRLEREEFRALCTELRVRPA--------------DAEAVFQRLDAD 73 Query: 160 KDGQLTLEEFCEG 172 +DG +T +EF G Sbjct: 74 RDGAITFQEFARG 86 >3A8R-A nrPDB Length = 179 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 61/154 (39%), Gaps = 19/154 (12%) Query: 32 KGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYI-------DFKE 84 K F + G L +S F K FA +F+ A K G + + K+ Sbjct: 32 KRFNQLQVDGVLLRSRFGKC----IGMDGSDEFAVQMFDSL-ARKRGIVKQVLTKDELKD 86 Query: 85 FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDT 144 F L+ +++L F + D + +G ++ +E+ I+ + S KL + ++ Sbjct: 87 FYEQLTDQGF---DNRLRTFFDMVDKNADGRLTAEEVKEII----ALSASANKLSKIKER 139 Query: 145 PEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPT 178 ++ I +D G + +E+ + P+ Sbjct: 140 ADEYTALIMEELDPTNLGYIEMEDLEALLLQSPS 173 Score = 28.8 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 25/64 (39%) Query: 124 IVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSAL 183 + + K + + R+ F+M+DKN DG+LT EE E + Sbjct: 75 VKQVLTKDELKDFYEQLTDQGFDNRLRTFFDMVDKNADGRLTAEEVKEIIALSASANKLS 134 Query: 184 SLYD 187 + + Sbjct: 135 KIKE 138 >2NLN-A nrPDB Length = 108 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 27/73 (36%), Gaps = 9/73 (12%) Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNK 160 + F+ D D +G + DE+ + + + E + + D + Sbjct: 43 VKDIFRFIDNDQSGYLDGDELKYFLQ---------KFQSDARELTESETKSLMDAADNDG 93 Query: 161 DGQLTLEEFCEGS 173 DG++ +EF E Sbjct: 94 DGKIGADEFQEMV 106 Score = 35.4 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Query: 44 NKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE---FICALSVTSRGELNDK 100 + E QK ++ ++ + +F D D++GY+D E F+ +R + Sbjct: 22 DTFEPQKFFQTSGLSKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESE 81 Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDA 127 D D +G I DE +V + Sbjct: 82 TKSLMDAADNDGDGKIGADEFQEMVHS 108 >6AGI-A nrPDB Length = 382 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 28/69 (40%), Gaps = 8/69 (11%) Query: 40 SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND 99 S + + EF++ VF +FD DK+ + +KEFI + D Sbjct: 320 SRSIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIM--------KD 371 Query: 100 KLIWAFQLY 108 +L F+ Y Sbjct: 372 RLHRGFRGY 380 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 30/134 (22%), Positives = 49/134 (36%), Gaps = 17/134 (12%) Query: 41 GHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDK 100 +++ +F I ++ + S F E V +K I F EF + + Sbjct: 254 NTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKG--ITFDEFRSFFQFLNNL---ED 308 Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNK 160 A +Y+ + I DE R V + S VN +F + D +K Sbjct: 309 FAIALNMYNF-ASRSIGQDEFKRAVYVATGLKFSP-----------HLVNTVFKIFDVDK 356 Query: 161 DGQLTLEEFCEGSK 174 D QL+ +EF K Sbjct: 357 DDQLSYKEFIGIMK 370 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 38/95 (40%), Gaps = 6/95 (6%) Query: 8 LSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEY 67 LS+ +L ++ T K + ++ + G ++ +E+ P A Sbjct: 56 LSKQELNQMLAETPPVWKGSSKLFRNLKEK---GVISYTEY---LFLLCILTKPHAGFRI 109 Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLI 102 FN+FD D N +D KEF+ + + ++ Sbjct: 110 AFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIK 144 >2M1U-A nrPDB Length = 93 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 3/67 (4%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 +K +L + + F D G ++ EF+ I + P A F D + G+ID+ Sbjct: 24 EKTQLIEAFYNFDGDY-DGFVSVEEFRGIIRDGLPMT--EAEITEFFEAADPNNTGFIDY 80 Query: 83 KEFICAL 89 K F L Sbjct: 81 KAFAAML 87 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 30/84 (35%), Gaps = 15/84 (17%) Query: 88 ALSVTSRGELNDK--LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTP 145 L ++K LI AF +D D +G +S +E I+ M Sbjct: 13 GLVPRGSHMSDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRDGLPM-------------T 59 Query: 146 EKRVNKIFNMMDKNKDGQLTLEEF 169 E + + F D N G + + F Sbjct: 60 EAEITEFFEAADPNNTGFIDYKAF 83 Score = 35.8 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Query: 58 FGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLIS 117 D F FD D +G++ +EF + ++ F+ D +N G I Sbjct: 21 MSDEKTQLIEAFYNFDGDYDGFVSVEEF-RGIIRDGLPMTEAEITEFFEAADPNNTGFID 79 Query: 118 YDEMLRIVDAIYK 130 Y ++ ++ + Sbjct: 80 YKAFAAMLYSVDE 92 >1BU3-A nrPDB Length = 109 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 36/98 (36%), Gaps = 11/98 (11%) Query: 78 GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 ++K F + +T++ D + AF + D D +G I DE+ + ++ Sbjct: 23 DSFNYKAFFAKVGLTAK--SADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALT- 79 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + D + DG + ++E+ K Sbjct: 80 --------DAETKAFLKAGDSDGDGAIGVDEWAALVKA 109 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 35/83 (42%), Gaps = 3/83 (3%) Query: 48 FQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE---FICALSVTSRGELNDKLIWA 104 ++ + + + + F V D DK+G+I+ E F+ S +R + + Sbjct: 27 YKAFFAKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAF 86 Query: 105 FQLYDLDNNGLISYDEMLRIVDA 127 + D D +G I DE +V A Sbjct: 87 LKAGDSDGDGAIGVDEWAALVKA 109 >5VT9-A nrPDB Length = 152 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 48/121 (39%), Gaps = 12/121 (9%) Query: 10 QDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVF 69 Q+ L+++V E + Y F G ++ + + +Q PS + F Sbjct: 10 QEALEEMV--------EADEMYARFNARASGGKVSTGDAMILARQLG--LAPSYADKQAF 59 Query: 70 NVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIY 129 D Y F++F+ S + D L+ AF +D+ +G ++ +M I+ Sbjct: 60 EEKSGDNLDYASFQKFV-GTSTHPEDNIED-LVEAFAYFDVSKHGYLTRKQMGNILMTYG 117 Query: 130 K 130 + Sbjct: 118 E 118 >1CB1-A nrPDB Length = 78 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 26 ELQQWYKGFF-KDCPSGHLNKSEFQKIYKQFFP-FGDPSAFAEYVFNVFDADKNGYIDFK 83 EL+ ++ + K+ L+K E +++ + FP + +F D + +G + F+ Sbjct: 8 ELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDGEVSFE 67 Query: 84 EFICALSVTSR 94 EF + S+ Sbjct: 68 EFQVLVKKISQ 78 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 39/88 (44%), Gaps = 18/88 (20%) Query: 93 SRGELNDKLIWAFQLY-----DLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEK 147 S + +L F+ Y D + +S +E+ +++ A + + + Sbjct: 1 SAQKSPAELKSIFEKYAAKEGDPNQ---LSKEELKQLIQAEFPSLLKGPR---------- 47 Query: 148 RVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 ++ +F +DKN DG+++ EEF K+ Sbjct: 48 TLDDLFQELDKNGDGEVSFEEFQVLVKK 75 Score = 27.3 bits (59), Expect = 3.7, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 16/30 (53%) Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 L FQ D + +G +S++E +V I + Sbjct: 49 LDDLFQELDKNGDGEVSFEEFQVLVKKISQ 78 >2LUC-A nrPDB Length = 105 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 29/78 (37%), Gaps = 11/78 (14%) Query: 99 DKLIWAFQLYDLDNNGL---ISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM 155 + LI FQ Y +G +S E L ++ K P ++++ Sbjct: 15 ESLIAVFQKY-AGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPG-------VLDRMMKK 66 Query: 156 MDKNKDGQLTLEEFCEGS 173 +D N DGQL EF Sbjct: 67 LDTNSDGQLDFSEFLNLI 84 Score = 36.5 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 29/82 (35%), Gaps = 8/82 (9%) Query: 22 FDKKELQQWYKGFFK----DCPSGHLNKSEFQKIY----KQFFPFGDPSAFAEYVFNVFD 73 ++ ++ F K D + L+K+EF F + + D Sbjct: 9 ETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLD 68 Query: 74 ADKNGYIDFKEFICALSVTSRG 95 + +G +DF EF+ + + Sbjct: 69 TNSDGQLDFSEFLNLIGGLAMA 90 Score = 26.5 bits (57), Expect = 7.4, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 30/87 (34%), Gaps = 10/87 (11%) Query: 52 YKQFFPFGDPSAFAEYVFNVFDA----DK-NGYIDFKEFICALSVTSRGELNDK-----L 101 + + E + VF D N + EF+ ++ ++ L Sbjct: 1 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL 60 Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAI 128 + D +++G + + E L ++ + Sbjct: 61 DRMMKKLDTNSDGQLDFSEFLNLIGGL 87 >1BOD-A nrPDB Length = 74 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 36/80 (45%), Gaps = 10/80 (12%) Query: 96 ELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM 155 + ++L F+ YD + +G ++ K++ + ++++F Sbjct: 2 KSPEELKGIFEKYDKEGDG--------QLSKEELKLLLQTEFPSLLKGMS--TLDELFEE 51 Query: 156 MDKNKDGQLTLEEFCEGSKR 175 +DKN DG+++ EEF K+ Sbjct: 52 LDKNGDGEVSFEEFQVLVKK 71 Score = 31.9 bits (71), Expect = 0.18, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 29/70 (41%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 +EL+ ++ + K+ + + +F + + +F D + +G + F+E Sbjct: 5 EELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEVSFEE 64 Query: 85 FICALSVTSR 94 F + S+ Sbjct: 65 FQVLVKKISQ 74 >1TTX-A nrPDB Length = 109 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 26/75 (34%), Gaps = 9/75 (12%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 +++ F+ D D +G + +E+ + E + D Sbjct: 42 NQVKDVFRFIDNDQSGYLDEEELK---------FFLQKFESGARELTESETKSLMAAADN 92 Query: 159 NKDGQLTLEEFCEGS 173 + DG++ EEF E Sbjct: 93 DGDGKIGAEEFQEMV 107 Score = 35.8 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Query: 44 NKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE---FICALSVTSRGELNDK 100 + E QK ++ + + VF D D++GY+D +E F+ +R + Sbjct: 23 DTFEPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESE 82 Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDA 127 D D +G I +E +V + Sbjct: 83 TKSLMAAADNDGDGKIGAEEFQEMVHS 109 Score = 34.6 bits (78), Expect = 0.025, Method: Composition-based stats. Identities = 12/76 (15%), Positives = 32/76 (42%), Gaps = 3/76 (3%) Query: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF--FPFGDPSAFAEYVFNVFDA 74 ++ +++ ++ F + SG+L++ E + ++F + + + D Sbjct: 34 SGLSKMSANQVKDVFR-FIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADN 92 Query: 75 DKNGYIDFKEFICALS 90 D +G I +EF + Sbjct: 93 DGDGKIGAEEFQEMVH 108 >3BOW-B nrPDB Length = 184 Score = 36.9 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 47/125 (37%), Gaps = 25/125 (20%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 + V D+D G + F+EF + K ++ +D D +G I +E+ +A Sbjct: 63 MVAVMDSDTTGKLGFEEFKYLWNNIK------KWQGIYKRFDTDRSGTIGSNELPGAFEA 116 Query: 128 IYKMVGSMVKLPEDEDTPEK--------------RVNKIFNMM---DKNKDGQL--TLEE 168 + + ++ R++ +F DKN GQ+ ++E Sbjct: 117 AGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQE 176 Query: 169 FCEGS 173 + + + Sbjct: 177 WLQLT 181 >1NSH-A nrPDB Length = 101 Score = 36.5 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 30/78 (38%), Gaps = 11/78 (14%) Query: 99 DKLIWAFQLYDLDNNG---LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNM 155 + LI FQ Y +G +S E L ++ K P ++++ Sbjct: 11 ESLIAVFQKY-AGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPG-------VLDRMMKK 62 Query: 156 MDKNKDGQLTLEEFCEGS 173 +D N DGQL +EF Sbjct: 63 LDLNSDGQLDFQEFLNLI 80 Score = 36.5 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 29/79 (36%), Gaps = 8/79 (10%) Query: 22 FDKKELQQWYKGFFK----DCPSGHLNKSEFQKIY----KQFFPFGDPSAFAEYVFNVFD 73 ++ ++ F K D S L+K+EF F + + D Sbjct: 5 ETERCIESLIAVFQKYAGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLD 64 Query: 74 ADKNGYIDFKEFICALSVT 92 + +G +DF+EF+ + Sbjct: 65 LNSDGQLDFQEFLNLIGGL 83 Score = 26.5 bits (57), Expect = 7.0, Method: Composition-based stats. Identities = 8/55 (14%), Positives = 23/55 (41%), Gaps = 5/55 (9%) Query: 79 YIDFKEFICALSVTSRGELNDK-----LIWAFQLYDLDNNGLISYDEMLRIVDAI 128 + EF+ ++ ++ L + DL+++G + + E L ++ + Sbjct: 29 TLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGGL 83 >2I18-A nrPDB Length = 64 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 16/74 (21%) Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNK 160 L ++L D+D +G ++ +E+ ++V + D N Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKKHGI----------------EKVAEQVMKADANG 50 Query: 161 DGQLTLEEFCEGSK 174 DG +TLEEF E S Sbjct: 51 DGYITLEEFLEFSL 64 Score = 31.9 bits (71), Expect = 0.18, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 26/56 (46%), Gaps = 4/56 (7%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLR 123 ++ + D D +G + +E ++ ++++ A D + +G I+ +E L Sbjct: 10 LYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKA----DANGDGYITLEEFLE 61 Score = 28.1 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 6/60 (10%) Query: 27 LQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFI 86 L+ YK D G L K E FF AE V DA+ +GYI +EF+ Sbjct: 7 LKVLYKLMDVD-GDGKLTKEE----VTSFFKKHGIEKVAEQVMKA-DANGDGYITLEEFL 60 >1QLS-A nrPDB Length = 99 Score = 36.2 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 31/85 (36%), Gaps = 8/85 (9%) Query: 16 LVRSTRFDKKELQQWYKGFFK----DCPSGHLNKSEFQKIY----KQFFPFGDPSAFAEY 67 + + ++ ++ F K D + ++K+EF F + Sbjct: 1 MAKRPTETERCIESLIAIFQKHAGRDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDR 60 Query: 68 VFNVFDADKNGYIDFKEFICALSVT 92 + D D +G +DF+EF+ + Sbjct: 61 MMKKLDLDSDGQLDFQEFLNLIGGL 85 Score = 35.8 bits (81), Expect = 0.012, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 24/62 (38%), Gaps = 7/62 (11%) Query: 112 NNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 NN IS E L ++ K P ++++ +D + DGQL +EF Sbjct: 28 NNTKISKTEFLIFMNTELAAFTQNQKDPG-------VLDRMMKKLDLDSDGQLDFQEFLN 80 Query: 172 GS 173 Sbjct: 81 LI 82 Score = 27.7 bits (60), Expect = 2.9, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 25/60 (41%), Gaps = 6/60 (10%) Query: 75 DKNGY-IDFKEFICALSVTSRGELNDK-----LIWAFQLYDLDNNGLISYDEMLRIVDAI 128 D N I EF+ ++ ++ L + DLD++G + + E L ++ + Sbjct: 26 DGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFLNLIGGL 85 >2MBX-A nrPDB Length = 109 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKE---FICALSVTSRGELNDKLIWAFQLYDLDNNGLI 116 A + VF + D DK+ +++ E F+ S +R + + + D D +G I Sbjct: 39 KSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAETKVFLKAGDSDGDGKI 98 Query: 117 SYDEMLRIVDA 127 DE ++ A Sbjct: 99 GVDEFGAMIKA 109 Score = 33.8 bits (76), Expect = 0.044, Method: Composition-based stats. Identities = 15/101 (14%), Positives = 34/101 (33%), Gaps = 11/101 (10%) Query: 75 DKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGS 134 G D K F + + ++ + + F++ D D + + DE+ + + Sbjct: 20 KAEGSFDHKAFFTKVGLAAKSPAD--IKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARA 77 Query: 135 MVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + D + DG++ ++EF K Sbjct: 78 ---------LSDAETKVFLKAGDSDGDGKIGVDEFGAMIKA 109 >1Q80-A nrPDB Length = 174 Score = 35.8 bits (81), Expect = 0.012, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 53/148 (35%), Gaps = 29/148 (19%) Query: 38 CPSGHLNKSEFQKIYKQFFPFGDPSAF-----AEYVFNVFD-----ADKNGYIDFKEFIC 87 G + + +F+ + ++F + A + + V+D ID FI Sbjct: 18 DKDGAITRMDFESMAERFAKESEMKAEHAKVLMDSLTGVWDNFLTAVAGGKGIDETTFIN 77 Query: 88 ALSVTSRGELNDKLIWA-----FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDE 142 ++ + ++ F+ D + + IS DE + M+G + Sbjct: 78 SMKEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDE----YGIFFGMLGLDKTMAPAS 133 Query: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 F+ +D N DG L+LEEF Sbjct: 134 ----------FDAIDTNNDGLLSLEEFV 151 Score = 29.6 bits (65), Expect = 0.85, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 30/76 (39%), Gaps = 5/76 (6%) Query: 30 WYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL 89 + ++++ E+ + + + F+ D + +G + +EF+ A Sbjct: 98 LFFRAVDTNEDNNISRDEYGIFFGMLGLDKTMAPAS---FDAIDTNNDGLLSLEEFVIAG 154 Query: 90 SVT--SRGELNDKLIW 103 S + G+ +K+ W Sbjct: 155 SDFFMNDGDSTNKVFW 170 Score = 26.5 bits (57), Expect = 7.5, Method: Composition-based stats. Identities = 7/34 (20%), Positives = 13/34 (38%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 K+ F D D +G I+ + + + K Sbjct: 6 QKMKTYFNRIDFDKDGAITRMDFESMAERFAKES 39 >5MKE-A nrPDB Length = 968 Score = 35.8 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 24/56 (42%), Gaps = 2/56 (3%) Query: 76 KNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 G ++F E L +G + ++ F YD D + ++ E ++ D + K Sbjct: 732 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKE 785 >6D1W-A nrPDB Length = 740 Score = 35.4 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 24/56 (42%), Gaps = 2/56 (3%) Query: 76 KNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 G ++F E L +G + ++ F YD D + ++ E ++ D + K Sbjct: 680 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKE 733 >6DS2-B nrPDB Length = 114 Score = 35.4 bits (80), Expect = 0.016, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 36/99 (36%), Gaps = 4/99 (4%) Query: 5 QSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAF 64 SK+SQ + F + ++ + L + + Q K+ Sbjct: 2 TSKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKK---ENKNEKV 58 Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW 103 E++ D + + + F+EFI ++ + ++K+ Sbjct: 59 IEHIMEDLDTNADKQLSFEEFIMLMARLTWA-SHEKMHE 96 Score = 33.1 bits (74), Expect = 0.080, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 140 EDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + E+ EK + I +D N D QL+ EEF R Sbjct: 50 KKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMAR 85 >1ZFS-A nrPDB Length = 93 Score = 35.0 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 25/61 (40%), Gaps = 4/61 (6%) Query: 36 KDCPSGHLNKSEFQKIY----KQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV 91 K+ L+K E + + F + + + D + +G +DF+EF+ ++ Sbjct: 21 KEGDKYKLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAA 80 Query: 92 T 92 Sbjct: 81 L 81 Score = 35.0 bits (79), Expect = 0.022, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 24/56 (42%), Gaps = 7/56 (12%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 +S E+ ++ + K + V+KI +D+N DG++ +EF Sbjct: 27 KLSKKELKDLLQTELSSFLDVQKDADA-------VDKIMKELDENGDGEVDFQEFV 75 >2EC6-B nrPDB Length = 133 Score = 35.0 bits (79), Expect = 0.020, Method: Composition-based stats. Identities = 13/124 (10%), Positives = 47/124 (37%), Gaps = 7/124 (5%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 +E+++ + G ++ ++ ++ + D + + G ++F Sbjct: 2 QEMKEAF-TMIDQNRDGFIDINDLKEEFSSLGRTPDDKELTAML-----KEAPGPLNFTM 55 Query: 85 FICALSVTSRGELNDK-LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDED 143 F+ S G +++ + AF ++D D ++ + + +++ + ++ Sbjct: 56 FLSIFSDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDLLENMGDNFNKDEMRMTFKE 115 Query: 144 TPEK 147 P + Sbjct: 116 APVE 119 Score = 28.8 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 13/90 (14%), Positives = 31/90 (34%), Gaps = 21/90 (23%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK---------------------MVGSMVK 137 ++ AF + D + +G I +++ ++ + M S+ Sbjct: 2 QEMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPDDKELTAMLKEAPGPLNFTMFLSIFS 61 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLE 167 E+ + F M D++ +L +E Sbjct: 62 DKLSGTDSEETIRNAFGMFDEDATKKLNIE 91 >2OS8-B nrPDB Length = 157 Score = 35.0 bits (79), Expect = 0.021, Method: Composition-based stats. Identities = 15/132 (11%), Positives = 52/132 (39%), Gaps = 8/132 (6%) Query: 19 STRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 T+ +K++Q+ + F G ++ ++ ++++ D + + Sbjct: 10 LTKLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAML-----KEA 64 Query: 77 NGYIDFKEFICALSVTSRGELNDK-LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 G ++F F+ S G +++ + AF ++D + ++ + + +++ + Sbjct: 65 PGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGDNFNKD 124 Query: 136 VKLPEDEDTPEK 147 ++ P + Sbjct: 125 EMRMTFKEAPVE 136 >1KQV-A nrPDB Length = 79 Score = 34.6 bits (78), Expect = 0.028, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 19/28 (67%) Query: 148 RVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 ++++F +DKN DG+++ EEF K+ Sbjct: 49 TLDELFEELDKNGDGEVSFEEFQVLVKK 76 Score = 28.1 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Query: 25 KELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDF 82 +EL+ ++ + + P+ + + +F + + +F D + +G + F Sbjct: 8 EELKGIFEKYAAKEGDPNQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEVSF 67 Query: 83 KEFICALSVTSR 94 +EF + S+ Sbjct: 68 EEFQVLVKKISQ 79 >6DU8-A nrPDB Length = 805 Score = 34.2 bits (77), Expect = 0.033, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 24/67 (35%), Gaps = 1/67 (1%) Query: 76 KNGYIDFKEFICALSVTSRGELN-DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGS 134 I F++F L E +L F +D D N ++ E ++ + + + Sbjct: 612 GEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVA 671 Query: 135 MVKLPED 141 + E Sbjct: 672 LNTEIEK 678 >2MJW-B nrPDB Length = 94 Score = 34.2 bits (77), Expect = 0.037, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 25/60 (41%), Gaps = 4/60 (6%) Query: 37 DCPSGHLNKSEFQKIYKQ----FFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVT 92 + + L K E + + ++ F G + + DA+ + +DF EFI ++ Sbjct: 22 EGSTQTLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAI 81 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 9/56 (16%), Positives = 21/56 (37%), Gaps = 7/56 (12%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 ++ E+ +++ + + V+K+ +D N D Q+ EF Sbjct: 27 TLTKGELKVLME-------KELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFI 75 >4I5K-A nrPDB Length = 285 Score = 33.8 bits (76), Expect = 0.040, Method: Composition-based stats. Identities = 24/170 (14%), Positives = 65/170 (38%), Gaps = 17/170 (10%) Query: 11 DQLQDLVRST-RFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEY 67 ++ +D+ + T F + Y F ++++++ ++ S E Sbjct: 98 EEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADL----SRYNDQASSSRIIER 153 Query: 68 VFNVFDADKN-----GYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 +F+ G + + +F+ L + + F+ D+D +G++S E+ Sbjct: 154 IFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYEL- 212 Query: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVN-KIFNMMDKNKDGQLTLEEFCE 171 + Y+ ++ E P + ++ +++ DG++TL + Sbjct: 213 ---EYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKR 259 >4C0K-A nrPDB Length = 423 Score = 33.8 bits (76), Expect = 0.049, Method: Composition-based stats. Identities = 30/164 (18%), Positives = 54/164 (32%), Gaps = 18/164 (10%) Query: 13 LQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFP---FGDPSAFAEYVF 69 + + T KK L + +K LN E ++ F + V Sbjct: 1 MMEEQELTSACKKSLVRIFK-ICDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVI 59 Query: 70 NVFDADK--NGYIDFKEFICALSVTSRGELNDKLIWAF-QLYDLDNNGLISYDEMLR--I 124 D N + K F+ L ++ WA + + G EM + + Sbjct: 60 QKNVPDGIYNDAVTLKGFL-FLHCLFIQRGRNETTWAVLRRF-----GYNDQLEMCQEYL 113 Query: 125 VDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEE 168 + GS +L ++ + +F D++ DG L+ EE Sbjct: 114 RPPLKIPPGSSTELSHRG---QQFLIAVFERYDRDGDGALSPEE 154 >2L50-A nrPDB Length = 102 Score = 33.5 bits (75), Expect = 0.052, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 21/55 (38%), Gaps = 7/55 (12%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 IS ++ + S K +K+ +D N DG+++ +E+ Sbjct: 31 KISKSSFREMLQKELNHMLSDTGN-------RKAADKLIQNLDANHDGRISFDEY 78 Score = 30.0 bits (66), Expect = 0.58, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 16/45 (35%) Query: 45 KSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL 89 + QK A+ + DA+ +G I F E+ + Sbjct: 38 REMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEYWTLI 82 Score = 30.0 bits (66), Expect = 0.61, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 8/70 (11%) Query: 81 DFKEFIC-----ALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 F+E + LS T + DKLI Q D +++G IS+DE ++ I + + Sbjct: 36 SFREMLQKELNHMLSDTGNRKAADKLI---QNLDANHDGRISFDEYWTLIGGITGPIAKL 92 Query: 136 VKLPEDEDTP 145 + E + + Sbjct: 93 IHEQEQQSSS 102 >1B7T-Y nrPDB Length = 156 Score = 33.5 bits (75), Expect = 0.057, Method: Composition-based stats. Identities = 18/132 (13%), Positives = 51/132 (38%), Gaps = 8/132 (6%) Query: 19 STRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADK 76 T+ +K++Q+ + F G ++K + + I +Q D + + Sbjct: 9 LTKLPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAML-----KEA 63 Query: 77 NGYIDFKEFICALSVTSRGELNDK-LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 G ++F F+ S G +++ + AF ++D ++ + + +++ + Sbjct: 64 PGPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGDNFNKD 123 Query: 136 VKLPEDEDTPEK 147 ++ P + Sbjct: 124 EMRMTFKEAPVE 135 >1NP8-A nrPDB Length = 159 Score = 33.5 bits (75), Expect = 0.066, Method: Composition-based stats. Identities = 18/120 (15%), Positives = 39/120 (32%), Gaps = 19/120 (15%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 + V D+D G + F+EF + + + ++ +D D +G I +E+ +A Sbjct: 59 MVAVMDSDTTGKLGFEEFKYLWNNIKKWQG------IYKRFDTDRSGTIGSNELPGAFEA 112 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYD 187 + + ++ G + + F R + A D Sbjct: 113 AGFHLNQHIYSMIIRRYSDET-------------GNMDFDNFISCLVRLDAMFRAFRSLD 159 >2KHN-A nrPDB Length = 121 Score = 33.1 bits (74), Expect = 0.073, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 18/45 (40%) Query: 141 DEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 P+ + +I+ + D N DG++ EF K + L Sbjct: 60 QSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQL 104 >2WCE-A nrPDB Length = 95 Score = 33.1 bits (74), Expect = 0.079, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 30/59 (50%), Gaps = 7/59 (11%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 +S E+ +++ K + + +K +D+ +++IF +D N+D Q+ +EF Sbjct: 30 TLSKGELKQLLT---KELANTIKNIKDKAV----IDEIFQGLDANQDEQVDFQEFISMV 81 Score = 31.9 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 27/58 (46%), Gaps = 4/58 (6%) Query: 42 HLNKSEFQKIY----KQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRG 95 L+K E +++ A + +F DA+++ +DF+EFI +++ + Sbjct: 30 TLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMVAIALKA 87 >3TS5-B nrPDB Length = 161 Score = 33.1 bits (74), Expect = 0.083, Method: Composition-based stats. Identities = 12/124 (9%), Positives = 48/124 (38%), Gaps = 7/124 (5%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 +E+++ + G ++ ++ ++++ D + + G ++F Sbjct: 23 QEMKEAF-TMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAML-----KEAPGPLNFTM 76 Query: 85 FICALSVTSRGELNDK-LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDED 143 F+ S G +++ + AF ++D + ++ + + +++ + ++ Sbjct: 77 FLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGDNFNKDEMRMTFKE 136 Query: 144 TPEK 147 P + Sbjct: 137 APVE 140 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 7/55 (12%), Positives = 22/55 (40%) Query: 91 VTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTP 145 +L ++ AF + D + +G I +++ + ++ + ++ P Sbjct: 15 ARLPQKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEAP 69 >2L0P-A nrPDB Length = 94 Score = 32.7 bits (73), Expect = 0.087, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 25/61 (40%), Gaps = 4/61 (6%) Query: 36 KDCPSGHLNKSEFQKIY----KQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV 91 K+ L+K E +++ F + V D + +G +DF+E++ ++ Sbjct: 22 KEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAA 81 Query: 92 T 92 Sbjct: 82 L 82 Score = 32.7 bits (73), Expect = 0.089, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 23/56 (41%), Gaps = 7/56 (12%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 +S E+ ++ + D V+K+ +D+N DG++ +E+ Sbjct: 28 KLSKKELKELLQT-------ELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYV 76 >2KGR-A nrPDB Length = 111 Score = 32.7 bits (73), Expect = 0.093, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 30/71 (42%), Gaps = 14/71 (19%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 K F +D +G ++ + I+ P+ ++ I+N+ D + Sbjct: 15 KYRQLFNSHDKTMSGHLTGPQARTILM--------------QSSLPQAQLASIWNLSDID 60 Query: 160 KDGQLTLEEFC 170 +DG+LT EEF Sbjct: 61 QDGKLTAEEFI 71 Score = 29.6 bits (65), Expect = 0.84, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Query: 28 QQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFIC 87 +Q + K SGHL + + I Q P A ++N+ D D++G + +EFI Sbjct: 17 RQLFNSHDKTM-SGHLTGPQARTILMQSSL---PQAQLASIWNLSDIDQDGKLTAEEFIL 72 Query: 88 ALSVTS 93 A+ + Sbjct: 73 AMHLID 78 Score = 28.8 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 31/74 (41%), Gaps = 4/74 (5%) Query: 67 YVFNVFDADKNGYIDFKEFICALSVTSRGELND-KLIWAFQLYDLDNNGLISYDEMLRIV 125 +FN D +G++ A ++ + L +L + L D+D +G ++ +E + + Sbjct: 18 QLFNSHDKTMSGHLTGP---QARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAM 74 Query: 126 DAIYKMVGSMVKLP 139 I + P Sbjct: 75 HLIDVAMSGQPLPP 88 >1WY9-A nrPDB Length = 147 Score = 32.3 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 31/78 (39%) Query: 71 VFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 FD + NG ID L + + +L + + SY + LR++ Sbjct: 56 EFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSGSEETFSYSDFLRMMLGKRS 115 Query: 131 MVGSMVKLPEDEDTPEKR 148 + M+ + E+++ KR Sbjct: 116 AILRMILMYEEKNKEHKR 133 Score = 27.3 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 5/69 (7%), Positives = 22/69 (31%), Gaps = 1/69 (1%) Query: 35 FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSR 94 F +G ++ +++ ++ + + + + +F+ + Sbjct: 57 FDLNGNGDIDIMSLKRMLEKL-GVPKTHLELKRLIREVSSGSEETFSYSDFLRMMLGKRS 115 Query: 95 GELNDKLIW 103 L L++ Sbjct: 116 AILRMILMY 124 >1KFU-L nrPDB Length = 699 Score = 32.3 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 26/128 (20%), Positives = 50/128 (39%), Gaps = 16/128 (12%) Query: 47 EFQKIYKQFFPFGDPSAFAEYVFNVFDADK---NGYID--FKEFICALSVTSRGELNDKL 101 E+ + F P D F VF+ AD + I+ +EF S +++D + Sbjct: 480 EYILVPSTFEPNKD-GDFCIRVFSEKKADYQAVDDEIEANLEEF-----DISEDDIDDGV 533 Query: 102 IWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 F + IS E+ I+ + + + + + + +M+D + Sbjct: 534 RRLFAQL-AGEDAEISAFELQTILRRVLAK----RQDIKSDGFSIETCKIMVDMLDSDGS 588 Query: 162 GQLTLEEF 169 G+L L+EF Sbjct: 589 GKLGLKEF 596 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 35/129 (27%), Gaps = 48/129 (37%) Query: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGY------ 79 E + SG L EF ++ + + + ++ D D++G Sbjct: 574 ETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNSYEM 626 Query: 80 -----------------------------IDFKEFICALSVTSRGELNDKLIWAFQLYDL 110 IDF F+ L + L F+ D Sbjct: 627 RKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRL------ETLFKIFKQLDP 680 Query: 111 DNNGLISYD 119 +N G I D Sbjct: 681 ENTGTIELD 689 >5HYD-A nrPDB Length = 99 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 22/61 (36%), Gaps = 7/61 (11%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 +S E+ ++ S K + V+KI +D NKD ++ EF Sbjct: 28 KLSKGELKLLLQRELTEFLSCQKET-------QLVDKIVQDLDANKDNEVDFNEFVVMVA 80 Query: 175 R 175 Sbjct: 81 A 81 Score = 30.4 bits (67), Expect = 0.53, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 20/45 (44%) Query: 48 FQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVT 92 Q+ +F + + + DA+K+ +DF EF+ ++ Sbjct: 38 LQRELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVAAL 82 >1DFK-Y nrPDB Length = 139 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 16/124 (12%), Positives = 48/124 (38%), Gaps = 7/124 (5%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 +E+++ + D G ++K + + I +Q D + + G ++F Sbjct: 7 QEMKEAFSMIDVD-RDGFVSKEDIKAISEQLGRAPDDKELTAML-----KEAPGPLNFTM 60 Query: 85 FICALSVTSRGELNDK-LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDED 143 F+ S G +++ + AF ++D ++ + + +++ + ++ Sbjct: 61 FLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGDNFNKDEMRMTFKE 120 Query: 144 TPEK 147 P + Sbjct: 121 APVE 124 >5CSF-A nrPDB Length = 95 Score = 31.9 bits (71), Expect = 0.18, Method: Composition-based stats. Identities = 8/46 (17%), Positives = 23/46 (50%) Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGS 173 + +++ + + +E ++ V+K+ +D + DG+ +EF Sbjct: 36 LKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFV 81 Score = 30.4 bits (67), Expect = 0.45, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 25/61 (40%), Gaps = 4/61 (6%) Query: 36 KDCPSGHLNKSEFQKI----YKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV 91 ++ L KSE +++ F + V D D +G DF+EF+ +++ Sbjct: 24 REGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAM 83 Query: 92 T 92 Sbjct: 84 V 84 >5W1A-B nrPDB Length = 155 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 39/107 (36%), Gaps = 17/107 (15%) Query: 80 IDFKEFICALSVTSRGELN---DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 I EF+ S + + + I +LYD + NG + E+ + A+ Sbjct: 61 IKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALG------- 113 Query: 137 KLPEDEDTPEKRVNKIFNM-MD-KNKDGQLTLEEFCEGSKRDPTIVS 181 E +++V +F MD ++ +G + F P + Sbjct: 114 -----ESLDDEQVETLFADCMDPEDDEGFIPYSPFLARMCDRPDQLK 155 >3H4S-E nrPDB Length = 135 Score = 31.5 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 25/79 (31%), Gaps = 1/79 (1%) Query: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 EL + + D + ++ G A+ + D D +G ++ E Sbjct: 40 SELCKGFSL-LADPERHLITAESLRRNSGILGIEGMSKEDAQGMVREGDLDGDGALNQTE 98 Query: 85 FICALSVTSRGELNDKLIW 103 F + S + D W Sbjct: 99 FCVLMVRLSPEMMEDAETW 117 Score = 29.6 bits (65), Expect = 0.81, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 16/41 (39%), Gaps = 1/41 (2%) Query: 142 EDTPEKRVNKIFNMMDKNKDGQLTLEEFCE-GSKRDPTIVS 181 E ++ + D + DG L EFC + P ++ Sbjct: 72 EGMSKEDAQGMVREGDLDGDGALNQTEFCVLMVRLSPEMME 112 >2JQ6-A nrPDB Length = 139 Score = 31.1 bits (69), Expect = 0.26, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 25/55 (45%), Gaps = 2/55 (3%) Query: 117 SYDEMLRIVDAIYKMV--GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 +YDE+ + + + + K P + KI+ + D +KDG L EEF Sbjct: 52 TYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 106 >1I84-U nrPDB Length = 166 Score = 31.1 bits (69), Expect = 0.27, Method: Composition-based stats. Identities = 13/96 (13%), Positives = 34/96 (35%), Gaps = 22/96 (22%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 + AF + D + +G+I D++ A+ ++ + + ++ + Sbjct: 25 EDFKEAFTVIDQNADGIIDKDDLRETFAAMGRL-----------NVKNEELDAMIKEA-- 71 Query: 159 NKDGQLTLEEF-------CEGSKRDPTIVSALSLYD 187 G + F +G+ + I+ A + D Sbjct: 72 --SGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLD 105 Score = 28.4 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 39/111 (35%), Gaps = 15/111 (13%) Query: 54 QFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNN 113 F + F E F V D + +G ID + + R + ++ + A + + Sbjct: 17 SMFDETEIEDFKE-AFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDA---MIKEAS 72 Query: 114 GLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 G I++ L + K PE + F ++D + G + Sbjct: 73 GPINFTVFLTMFGEKLKGAD-----------PEDVIMGAFKVLDPDGKGSI 112 Score = 28.1 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 32/95 (33%) Query: 40 SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELND 99 SG +N + F ++ + DP F V D D G I L+ + Sbjct: 72 SGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPE 131 Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGS 134 ++ + + D G + Y + ++ G Sbjct: 132 EIKNMWAAFPPDVAGNVDYKNICYVITHGEDAEGE 166 >4HRG-A nrPDB Length = 115 Score = 31.1 bits (69), Expect = 0.27, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 33/71 (46%), Gaps = 8/71 (11%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 + +++ F + D G ++ +++ +++ + K P V+KI +D+ Sbjct: 11 ETMMFTFHKFAGDK-GYLTKEDLRVLMEKEFPGFLENQKDPLA-------VDKIMKDLDQ 62 Query: 159 NKDGQLTLEEF 169 +DG++ + F Sbjct: 63 CRDGKVGFQSF 73 >4FTG-A nrPDB Length = 96 Score = 31.1 bits (69), Expect = 0.27, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 33/71 (46%), Gaps = 8/71 (11%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 + +++ F + D G ++ +++ +++ + K P V+KI +D+ Sbjct: 9 ETMMFTFHKFAGDK-GYLTKEDLRVLMEKEFPGFLENQKDPLA-------VDKIMKDLDQ 60 Query: 159 NKDGQLTLEEF 169 +DG++ + F Sbjct: 61 CRDGKVGFQSF 71 >5X2E-A nrPDB Length = 80 Score = 31.1 bits (69), Expect = 0.31, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 28/80 (35%), Gaps = 14/80 (17%) Query: 99 DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 D I F D D +ISY E+ + V + + V K + D Sbjct: 1 DSFINIFVSIDKDGTNVISYPELEQYV--------------AENNLDPSMVEKWKQLFDP 46 Query: 159 NKDGQLTLEEFCEGSKRDPT 178 + G +TLE FC P Sbjct: 47 DNTGSITLETFCSKLGLKPA 66 Score = 30.4 bits (67), Expect = 0.46, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 21/54 (38%), Gaps = 2/54 (3%) Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 +F D D I + E ++ + + QL+D DN G I+ + Sbjct: 6 IFVSIDKDGTNVISYPELEQYVAENNLDPSM--VEKWKQLFDPDNTGSITLETF 57 >2KFH-A nrPDB Length = 105 Score = 31.1 bits (69), Expect = 0.32, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 25/55 (45%), Gaps = 2/55 (3%) Query: 117 SYDEMLRIVDAIYKMV--GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 +YDE+ + + + + K P + KI+ + D +KDG L EEF Sbjct: 18 TYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 72 >2JXC-A nrPDB Length = 100 Score = 30.8 bits (68), Expect = 0.34, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 14/26 (53%) Query: 144 TPEKRVNKIFNMMDKNKDGQLTLEEF 169 P + +++ + D + DG L +EF Sbjct: 45 LPVDILGRVWELSDIDHDGMLDRDEF 70 Score = 28.4 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 23/57 (40%), Gaps = 4/57 (7%) Query: 34 FFKDCP-SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL 89 F P +G L+ + + + P V+ + D D +G +D EF A+ Sbjct: 21 FDSLSPVNGFLSGDKVKPV---LLNSKLPVDILGRVWELSDIDHDGMLDRDEFAVAM 74 >1NUB-A nrPDB Length = 229 Score = 30.8 bits (68), Expect = 0.34, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 25/70 (35%), Gaps = 15/70 (21%) Query: 101 LIWAFQLYDLDN-NGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + W F D +G +S+ E+ + + M E + F D + Sbjct: 157 VHWQFGQLDQHPIDGYLSHTELAPLRAPLIPM--------------EHCTTRFFETCDLD 202 Query: 160 KDGQLTLEEF 169 D + L+E+ Sbjct: 203 NDKYIALDEW 212 >2Y5I-A nrPDB Length = 99 Score = 30.8 bits (68), Expect = 0.37, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 7/56 (12%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 +S E+ +++A K P V KI N +D NKD ++ EF Sbjct: 28 KLSKGELKELLNAELTDFLMSQKDP-------MLVEKIMNDLDSNKDNEVDFNEFV 76 Score = 28.8 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 4/55 (7%) Query: 42 HLNKSEFQKIYKQ----FFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVT 92 L+K E +++ F E + N D++K+ +DF EF+ ++ Sbjct: 28 KLSKGELKELLNAELTDFLMSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVAAL 82 >1QJT-A nrPDB Length = 99 Score = 30.8 bits (68), Expect = 0.42, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 25/62 (40%) Query: 31 YKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALS 90 Y+ +++ +G+ + G P ++++ D D G + +EF AL Sbjct: 13 YEKYYRQVEAGNTGRVLALDAAAFLKKSGLPDLILGKIWDLADTDGKGVLSKQEFFVALR 72 Query: 91 VT 92 + Sbjct: 73 LV 74 Score = 28.8 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 17/30 (56%) Query: 140 EDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 + P+ + KI+++ D + G L+ +EF Sbjct: 38 KKSGLPDLILGKIWDLADTDGKGVLSKQEF 67 >1SNL-A nrPDB Length = 103 Score = 30.4 bits (67), Expect = 0.47, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 36/77 (46%), Gaps = 4/77 (5%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI----FNMMDKNK 160 F L+D++++G++ E+ + + V +D E+ ++ +D N+ Sbjct: 26 FILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVDTNQ 85 Query: 161 DGQLTLEEFCEGSKRDP 177 D +TLEEF ++R Sbjct: 86 DRLVTLEEFLASTQRKE 102 >4PCW-A nrPDB Length = 94 Score = 30.4 bits (67), Expect = 0.47, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 16/38 (42%) Query: 52 YKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICAL 89 ++Q D + + D D N IDF EF+ + Sbjct: 43 FRQILKNPDDPDMVDVFMDHLDIDHNKKIDFTEFLLMV 80 >2VTG-A nrPDB Length = 150 Score = 30.4 bits (67), Expect = 0.48, Method: Composition-based stats. Identities = 17/111 (15%), Positives = 44/111 (39%), Gaps = 18/111 (16%) Query: 83 KEFICALSVTSRGELNDKLIWAFQL----YDLDNNGLISYDEMLRIVDAIYKMVGSMVKL 138 +EF+C + L +KL AF+ +DL+N G I + R+++ + + Sbjct: 31 REFLCDQKYSDEENLPEKL-TAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHL--- 86 Query: 139 PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK-RDPTIVSALSLYDG 188 + K+ + + ++ +F + ++ + +++G Sbjct: 87 ---------EMKKMISEVTGGVSDTISYRDFVNMMLGKRSAVLKLVMMFEG 128 Score = 27.7 bits (60), Expect = 2.8, Method: Composition-based stats. Identities = 5/63 (7%), Positives = 24/63 (38%), Gaps = 2/63 (3%) Query: 27 LQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFI 86 ++ Y F + G ++ +++ ++ + + + + I +++F+ Sbjct: 52 FKEKYMEFDLNNE-GEIDLMSLKRMMEKL-GVPKTHLEMKKMISEVTGGVSDTISYRDFV 109 Query: 87 CAL 89 + Sbjct: 110 NMM 112 >2AUC-A nrPDB Length = 126 Score = 30.4 bits (67), Expect = 0.56, Method: Composition-based stats. Identities = 15/104 (14%), Positives = 37/104 (35%), Gaps = 4/104 (3%) Query: 32 KGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSV 91 F +G L + ++ + + D Y + E++ V Sbjct: 2 DMFNTKSSNGKLRIEDASHNARKLGLAPSSTDEKK--IRDLYGDSLTYEQYLEYLTMC-V 58 Query: 92 TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 R + ++LI F +D +++G ++ ++M I+ + Sbjct: 59 HDRDNM-EELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQ 101 >4YBH-B nrPDB Length = 92 Score = 30.0 bits (66), Expect = 0.57, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 27 LQQWYKGFF-KDCPSGHLNKSEFQKIYKQFFPFGD--PSAFAEYVFNVFDADKNGYIDFK 83 L + + ++ L+K E +++ ++ G A + D +K+ ++F+ Sbjct: 14 LVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQ 73 Query: 84 EFICALSVT 92 E++ L Sbjct: 74 EYVTFLGAL 82 Score = 27.7 bits (60), Expect = 3.0, Method: Composition-based stats. Identities = 8/56 (14%), Positives = 23/56 (41%), Gaps = 9/56 (16%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 +S E+ ++ +L + + ++ +D+NKD ++ +E+ Sbjct: 30 TLSKKELKELIQ---------KELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYV 76 >2MHH-A nrPDB Length = 96 Score = 30.0 bits (66), Expect = 0.61, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 34/82 (41%), Gaps = 2/82 (2%) Query: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYD 119 D A + DA+ + ++DF E+ L RG + + F YD+D + ++ + Sbjct: 15 DKIADIQEALAHADANADQHLDFDEWRQEL--KCRGHADADIEAVFAKYDVDGDRVLDAE 72 Query: 120 EMLRIVDAIYKMVGSMVKLPED 141 E +++ + + + Sbjct: 73 EQMKMAHDLEGQKSDLNNQLAE 94 >5MVF-A nrPDB Length = 523 Score = 30.0 bits (66), Expect = 0.63, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 23/54 (42%), Gaps = 2/54 (3%) Query: 118 YDEMLRIVDAIYKMVG--SMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 YDE+ + I + + K P + KI+ + D + DG L EEF Sbjct: 433 YDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEF 486 >3MNP-A nrPDB Length = 261 Score = 30.0 bits (66), Expect = 0.69, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 30/84 (35%), Gaps = 5/84 (5%) Query: 8 LSQDQLQDLVRSTRFDK---KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP-SA 63 LS + L FD+ +++ K K + N F ++ K D Sbjct: 156 LSSVPKEGLKSQELFDEIRMTYIKELGKAIAKRGGNSSQNWQRFYQLTKLLDSMHDVVEN 215 Query: 64 FAEYVFNVFDADKNGYIDFKEFIC 87 Y F F DK+ I+F E + Sbjct: 216 LLSYCFQTF-LDKSMSIEFPEMLA 238 >5HLO-A nrPDB Length = 94 Score = 30.0 bits (66), Expect = 0.73, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 28/62 (45%), Gaps = 3/62 (4%) Query: 45 KSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICA---LSVTSRGELNDKL 101 + + +K+ + P A+ F D + +G ++F+EF+ + V + + +++ Sbjct: 32 RDDLKKLLETECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEES 91 Query: 102 IW 103 Sbjct: 92 HK 93 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 13/25 (52%) Query: 146 EKRVNKIFNMMDKNKDGQLTLEEFC 170 +K + F +D N DG + +EF Sbjct: 49 KKGADVWFKELDINTDGAVNFQEFL 73 >1C07-A nrPDB Length = 95 Score = 29.6 bits (65), Expect = 0.82, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 25/70 (35%), Gaps = 14/70 (20%) Query: 100 KLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 K F D D +G +S E+ I P + I+++ D Sbjct: 11 KYDEIFLKTDKDMDGFVSGLEVREIF--------------LKTGLPSTLLAHIWSLCDTK 56 Query: 160 KDGQLTLEEF 169 G+L+ ++F Sbjct: 57 DCGKLSKDQF 66 >5KU1-A nrPDB Length = 424 Score = 29.6 bits (65), Expect = 0.83, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 22/56 (39%), Gaps = 5/56 (8%) Query: 140 EDEDTPE--KRVNKIFNMMDKNKDGQLTLEE---FCEGSKRDPTIVSALSLYDGLV 190 E E P K + +IF + D++ DG L E F P AL +V Sbjct: 2 EKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVV 57 Score = 27.3 bits (59), Expect = 3.7, Method: Composition-based stats. Identities = 7/21 (33%), Positives = 13/21 (61%) Query: 101 LIWAFQLYDLDNNGLISYDEM 121 L F++ D DN+G ++ E+ Sbjct: 13 LTRIFKISDQDNDGTLNDAEL 33 >6HIV-CJ nrPDB Length = 817 Score = 29.6 bits (65), Expect = 0.86, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 21/45 (46%), Gaps = 1/45 (2%) Query: 52 YKQFFPFGDPSAFAEYVFNVFDADKNGYIDF-KEFICALSVTSRG 95 Y+ + P+AF FN FDA Y+ + +EF SRG Sbjct: 87 YRPWSASAPPNAFRFRPFNEFDAKGREYVQYMREFARFDPRKSRG 131 >5LXV-B nrPDB Length = 88 Score = 29.6 bits (65), Expect = 0.93, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 22/49 (44%), Gaps = 5/49 (10%) Query: 73 DADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 D D +G +D + I G+ F+ DL+ +G+I D++ Sbjct: 27 DLDGDGEVDVFDLILMRKAVENGDTER-----FEAADLNCDGVIDSDDL 70 >5W2O-A nrPDB Length = 439 Score = 29.6 bits (65), Expect = 0.96, Method: Composition-based stats. Identities = 8/40 (20%), Positives = 16/40 (40%) Query: 77 NGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLI 116 G I+ + + ND+ A + +D D +G + Sbjct: 222 EGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFV 261 >4A7Z-A nrPDB Length = 900 Score = 29.2 bits (64), Expect = 0.97, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 26/73 (35%), Gaps = 3/73 (4%) Query: 37 DCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGE 96 P+G + + + F P + + D D +G EF+ A+ + Sbjct: 307 GSPTGIVRAEWTRHVLDVFGPLNGKHTGSIHQVVCADIDGDGE---DEFLVAMMGADPPD 363 Query: 97 LNDKLIWAFQLYD 109 +W ++L D Sbjct: 364 FQRTGVWCYKLVD 376 >1DJX-A nrPDB Length = 624 Score = 29.2 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 15/36 (41%) Query: 140 EDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKR 175 + + ++ DKNKD ++ +E + K Sbjct: 4 DQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKE 39 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 28/79 (35%), Gaps = 12/79 (15%) Query: 90 SVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRV 149 S+ R +L + + D + + +++ E+ + + V + Sbjct: 2 SMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQV------------DDGYA 49 Query: 150 NKIFNMMDKNKDGQLTLEE 168 KIF D ++ L EE Sbjct: 50 RKIFRECDHSQTDSLEDEE 68 Score = 26.5 bits (57), Expect = 6.9, Method: Composition-based stats. Identities = 11/82 (13%), Positives = 24/82 (29%) Query: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 D +K+ ++FKE L + + F+ D + +E+ Sbjct: 13 IHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQTDSLEDEEIETF 72 Query: 125 VDAIYKMVGSMVKLPEDEDTPE 146 + + E + E Sbjct: 73 YKMLTQRAEIDRAFEEAAGSAE 94 >4F8X-A nrPDB Length = 335 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 44/117 (37%), Gaps = 10/117 (8%) Query: 50 KIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYD 109 K+ KQ F P+ ++++ + + + + ++F+ L+WA Q+ D Sbjct: 35 KVLKQNFGEITPANAMKFMYTETEQNVFNFTEGEQFLEVAERFGSKVRCHNLVWASQVSD 94 Query: 110 LDNNGLISYDEMLRIVDA-IYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLT 165 + + E+ ++ I+K V + D + + N DG + Sbjct: 95 FVTSKTWTAKELTAVMKNHIFKTVQHFGRRCYSWDVVNEAL---------NGDGTFS 142 >4V1O-Q nrPDB Length = 734 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 20/35 (57%) Query: 70 NVFDADKNGYIDFKEFICALSVTSRGELNDKLIWA 104 ++ DA +G ++ KEF ++ G N KL++A Sbjct: 677 DIIDAIGDGKVNVKEFGKSIRRRYPGAENKKLMFA 711 >5OLW-A nrPDB Length = 227 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 35/84 (41%), Gaps = 10/84 (11%) Query: 107 LYDLDNNGLISYDEMLRIVDAIYKMVG-----SMVKLPEDEDTPEKRVNKIFNMMDKNKD 161 L+DLD + + R A+ + +G + E + KI ++ DK Sbjct: 6 LFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILDLADK--- 62 Query: 162 GQLTLEEFCEGSKR-DPTIVSALS 184 +++ EEF E +KR + V + Sbjct: 63 -KVSAEEFKELAKRKNDNYVKMIQ 85 >3TQO-A nrPDB Length = 462 Score = 28.8 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 18/131 (13%), Positives = 44/131 (33%), Gaps = 13/131 (9%) Query: 35 FKDCPSGHLNKSEFQKIYKQF--FPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVT 92 ++ +G L F + S++ + + D D N I F + Sbjct: 309 KENLENGRLALERFYLALRGLPVVNHEKTSSYTDRFYEAMDDDFNTPIAFALLFEMVREI 368 Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152 +R N+++ A + E+ + I+ ++ + E V +I Sbjct: 369 NRFRDNNQIEKA----------AVLAAELK-CLGNIFGLLQYSPEQFLQGAKKEADVQEI 417 Query: 153 FNMMDKNKDGQ 163 ++D+ + + Sbjct: 418 KKLIDQRNEAR 428 >2KAY-A nrPDB Length = 92 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Query: 27 LQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGD-PSAFAEYVFNVFDADKNGYIDFKEF 85 + ++K ++ L++ E +++ K+ G+ + + + D + + IDFKE+ Sbjct: 13 VTTFHKYSGREGSKLTLSRKELKELIKKELCLGEMKESSIDDLMKSLDKNSDQEIDFKEY 72 Query: 86 ICALSVT 92 L++ Sbjct: 73 SVFLTML 79 >1SJJ-A nrPDB Length = 863 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 26/171 (15%), Positives = 57/171 (33%), Gaps = 16/171 (9%) Query: 10 QDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYV- 68 Q+ L + T + + ++ ++ +N+ E Q + + Sbjct: 672 QEALIFDNKHTNYTMEHIRVGWEQLLTTIAR-TINEVENQILTRDAKGISQEQMNEFRAS 730 Query: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 FN FD K G +D ++F L + + D + G++++ + + Sbjct: 731 FNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPNRMGVVTFQAFIDFM--- 787 Query: 129 YKMVGSMVKLPEDEDTPEKRVNKI-FNMMDKNKDGQLTLEEFCEGSKRDPT 178 + D DT ++ + DKN +T++E D Sbjct: 788 -------SRETADTDTADQVMASFKILAGDKN---YITVDELRRELPPDQA 828 >5CUU-A nrPDB Length = 414 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 35/92 (38%), Gaps = 16/92 (17%) Query: 81 DFKEF-ICALSVTSRGELNDK--LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVK 137 + EF + A +K + F +D+ G + ++ + + +++ Sbjct: 57 NVTEFDLVAYGKDEFTLSMEKRVMARMFSAFDVTQLGYLEERKIEHMCKYLGRVMN---- 112 Query: 138 LPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 E V ++ + ++ DG +T E+F Sbjct: 113 --------EDDVKQMKSEINA-IDGHITFEKF 135 >3FSR-A nrPDB Length = 352 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 15/36 (41%), Gaps = 2/36 (5%) Query: 38 CPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFD 73 CP G L + F+ DPS +VF FD Sbjct: 295 CPGGRLRMERLIDLV--FYKRVDPSKLVTHVFRGFD 328 >3FPC-A nrPDB Length = 352 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 15/36 (41%), Gaps = 2/36 (5%) Query: 38 CPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFD 73 CP G L + F+ DPS +VF FD Sbjct: 295 CPGGRLRMERLIDLV--FYKRVDPSKLVTHVFRGFD 328 >2QPT-A nrPDB Length = 550 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 15/26 (57%) Query: 144 TPEKRVNKIFNMMDKNKDGQLTLEEF 169 P + +I+ + D ++DG L EEF Sbjct: 488 LPNSVLGRIWKLSDVDRDGMLDDEEF 513 Score = 27.7 bits (60), Expect = 3.0, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 45/122 (36%), Gaps = 8/122 (6%) Query: 34 FFKDCPSGHL-NKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVT 92 F + P + + E + ++ D S + E +N+ AD + Sbjct: 429 FVERGPDEAIEDGEEGSEDDAEWVVTKDKSKYDEIFYNLAPADGK----LSGSKAKTWMV 484 Query: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEML---RIVDAIYKMVGSMVKLPEDEDTPEKRV 149 N L ++L D+D +G++ +E +++A + G LP P KR Sbjct: 485 GTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPTNLPRRLVPPSKRR 544 Query: 150 NK 151 K Sbjct: 545 QK 546 >2JMM-A nrPDB Length = 156 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 7/12 (58%), Positives = 7/12 (58%) Query: 109 DLDNNGLISYDE 120 D D NG IS E Sbjct: 90 DKDGNGYISAAE 101 >1YKF-A nrPDB Length = 352 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 15/36 (41%), Gaps = 2/36 (5%) Query: 38 CPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFD 73 CP G L + F+ DPS +VF FD Sbjct: 295 CPGGRLRMERLIDLV--FYKRVDPSKLVTHVFRGFD 328 >2JTT-A nrPDB Length = 90 Score = 28.4 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 27/59 (45%), Gaps = 2/59 (3%) Query: 36 KDCPSGHLNKSEFQKIYKQFFPFGD--PSAFAEYVFNVFDADKNGYIDFKEFICALSVT 92 K+ L+K E +++ ++ G A + + D +K+ ++F+E+I L Sbjct: 22 KEGDKHTLSKKELKELIQKELTIGSKLQDAEIVKLMDDLDRNKDQEVNFQEYITFLGAL 80 >6EMI-A nrPDB Length = 532 Score = 28.4 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 12/26 (46%), Positives = 15/26 (57%), Gaps = 1/26 (3%) Query: 33 GFFKDCPSGHLNKSEFQKIYKQFFPF 58 GF KD S + + EFQ+ K FFP Sbjct: 339 GFSKDNDS-IITRKEFQEGLKVFFPN 363 >2K60-A nrPDB Length = 150 Score = 28.4 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 22/44 (50%) Query: 133 GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRD 176 GS + EDE + V I +MD + +G + +EE E + D Sbjct: 1 GSHMASSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLRED 44 >2KLD-A nrPDB Length = 123 Score = 28.4 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 24/56 (42%), Gaps = 2/56 (3%) Query: 76 KNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 G ++F E L +G + ++ F YD D + ++ E ++ D + K Sbjct: 59 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKE 112 >1FI6-A nrPDB Length = 92 Score = 28.4 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 14/66 (21%) Query: 105 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQL 164 F+ D NG I + K + KLP E ++ I+ + D +KDG L Sbjct: 15 FKTIQPDLNGFIP--------GSAAKEFFTKSKLPILE------LSHIWELSDFDKDGAL 60 Query: 165 TLEEFC 170 TL+EFC Sbjct: 61 TLDEFC 66 >3NSO-A nrPDB Length = 101 Score = 28.4 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 33/65 (50%), Gaps = 5/65 (7%) Query: 31 YKGFFKDCPSG-HLNKSEFQKIYKQFFPFGDPSAFAEYVFNVF----DADKNGYIDFKEF 85 ++ + C L ++E +++ ++ P+ F E +N F D +K+ +DF E+ Sbjct: 16 FQEYAGRCGDKYKLCQAELKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEY 75 Query: 86 ICALS 90 + +L+ Sbjct: 76 VRSLA 80 >1SRA-A nrPDB Length = 151 Score = 28.1 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 25/70 (35%), Gaps = 15/70 (21%) Query: 101 LIWAFQLYDLDN-NGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 + W F D +G +S+ E+ + + M E + F D + Sbjct: 79 VHWQFGQLDQHPIDGYLSHTELAPLRAPLIPM--------------EHCTTRFFETCDLD 124 Query: 160 KDGQLTLEEF 169 D + L+E+ Sbjct: 125 NDKYIALDEW 134 >4I0B-A nrPDB Length = 222 Score = 28.1 bits (61), Expect = 2.8, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 19/39 (48%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIF 153 I+ E+ +IV + VG ++K+ ED++ I Sbjct: 179 KITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIV 217 >6QAA-A nrPDB Length = 557 Score = 27.7 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 12/25 (48%), Positives = 15/25 (60%), Gaps = 1/25 (4%) Query: 33 GFFKDCPSGHLNKSEFQKIYKQFFP 57 GF KD S + + EFQ+ K FFP Sbjct: 364 GFSKDNNS-IITRKEFQEGLKIFFP 387 Score = 27.3 bits (59), Expect = 4.2, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 23/66 (34%), Gaps = 1/66 (1%) Query: 34 FFKDCPSGHLNKSEFQKIYKQFFPFGDP-SAFAEYVFNVFDADKNGYIDFKEFICALSVT 92 F D P L +F+K D +AF Y F D N I KEF L + Sbjct: 326 FLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF 385 Query: 93 SRGELN 98 G Sbjct: 386 FPGVSE 391 >4QHP-A nrPDB Length = 870 Score = 27.7 bits (60), Expect = 3.2, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 10/79 (12%) Query: 9 SQDQLQDLVRSTRFDK-KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEY 67 S +++ + T ++K E+ + Y L + FQK K +F D A Sbjct: 367 SYEEMNNFYTMTVYEKGAEVVRMYHT--------LLGEEGFQKGMKLYFQRHDGQAVTCD 418 Query: 68 VFNVFDADKNGYIDFKEFI 86 F AD NG I+ +F Sbjct: 419 DFRAAMADANG-INLDQFA 436 >4AOM-A nrPDB Length = 146 Score = 27.3 bits (59), Expect = 3.8, Method: Composition-based stats. Identities = 14/95 (14%), Positives = 40/95 (42%), Gaps = 15/95 (15%) Query: 78 GYIDFKEFICALSVTSRGELN-DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 + +++++ LS+ + N ++LI F +D + G ++ +M I+ + Sbjct: 62 DNLTYEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDAL---- 117 Query: 137 KLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 T ++ ++ + ++ + + FCE Sbjct: 118 -------TDQEAIDALNAFSSEDN---IDYKLFCE 142 >3KCC-A nrPDB Length = 260 Score = 27.3 bits (59), Expect = 4.0, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 19/39 (48%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIF 153 I+ E+ +IV + VG ++K+ ED++ I Sbjct: 217 KITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIV 255 >3GBX-A nrPDB Length = 420 Score = 27.3 bits (59), Expect = 4.0, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 17/35 (48%), Gaps = 2/35 (5%) Query: 158 KNKDGQLTLEEFCEGSKRD--PTIVSALSLYDGLV 190 ++ G++ +E + +K I+ S Y G+V Sbjct: 150 IDESGKIDYDEMAKLAKEHKPKMIIGGFSAYSGVV 184 >2CXJ-A nrPDB Length = 98 Score = 27.3 bits (59), Expect = 4.1, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 27/66 (40%), Gaps = 1/66 (1%) Query: 36 KDCPSGHLNKSEFQKIYKQFFP-FGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSR 94 ++ G LN +EF+++ Q P + D +++ + F E+ + ++ Sbjct: 26 REGRKGSLNINEFKELATQQLPHLLKDVGSLDEKMKTLDVNQDSELRFSEYWRLIGELAK 85 Query: 95 GELNDK 100 +K Sbjct: 86 EVRKEK 91 >2GS4-A nrPDB Length = 166 Score = 27.3 bits (59), Expect = 4.2, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 3/73 (4%) Query: 87 CALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPE 146 AL+ +R N+KL AF + + +G I + ++V++ + +K E E Sbjct: 26 RALAKLARATSNEKLSQAFHAHLEETHGQIER--IDQVVESESNLKIKRMKCVAMEGLIE 83 Query: 147 KRVNKIFNMMDKN 159 + N++ +KN Sbjct: 84 E-ANEVIESTEKN 95 >2G2B-A nrPDB Length = 150 Score = 27.3 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 29/77 (37%) Query: 71 VFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 FD + NG ID L + + +L + SY + LR++ Sbjct: 59 EFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKRS 118 Query: 131 MVGSMVKLPEDEDTPEK 147 + M+ + E++ ++ Sbjct: 119 AILKMILMYEEKAREKE 135 >5LJ6-A nrPDB Length = 664 Score = 27.3 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 36/103 (34%), Gaps = 13/103 (12%) Query: 18 RSTRFDKKELQQWYKGFFKDCP--------SGHLNKSEFQKIYKQFFPFGDPSAFAEYVF 69 R + + E++Q + F + S + + +F I Q G + + Sbjct: 17 RGSHMNIIEIKQLNRYFGEGENRVHVLKDISLSIERGDFVAIMGQ---SGSGKSTLMNII 73 Query: 70 NVFDA--DKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDL 110 D + ID KE I + + K + FQ Y+L Sbjct: 74 GCLDTATGGSSKIDGKETIELTNDQLSDLRSQKFGFIFQRYNL 116 >2JBS-A nrPDB Length = 422 Score = 27.3 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 19/47 (40%), Gaps = 3/47 (6%) Query: 39 PSGHLNKSEFQKIYKQFFPFGDPSAFAEYV---FNVFDADKNGYIDF 82 P G + + E I + + AEY FN FDAD N F Sbjct: 150 PFGKVEEVEGGIILNGDYGWSSGCDHAEYAIVGFNRFDADGNKIYSF 196 >4CZY-B nrPDB Length = 429 Score = 26.9 bits (58), Expect = 4.9, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 30/94 (31%), Gaps = 22/94 (23%) Query: 23 DKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP---------------SAFAEY 67 D+KE ++ +G + + F+ GD F +Y Sbjct: 302 DEKEFH-----LMRELENGRIARLMFK--LSVVNERGDSCGVHNWSETGERLLLKLFRDY 354 Query: 68 VFNVFDADKNGYIDFKEFICALSVTSRGELNDKL 101 VF+ DAD +D ++ LS L Sbjct: 355 VFHQVDADGKARLDTNHYLNCLSKLDASSEEQIL 388 >2G0Q-A nrPDB Length = 173 Score = 26.9 bits (58), Expect = 5.0, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 22/63 (34%), Gaps = 3/63 (4%) Query: 116 ISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI---FNMMDKNKDGQLTLEEFCEG 172 ++ DE+ + + ED EK K N D + G+ EE+ Sbjct: 79 VTSDELENLDAVEGNEYERVTVGIVREDNSEKMAVKTYMWINKADPDMFGEWNFEEWKRL 138 Query: 173 SKR 175 K+ Sbjct: 139 HKK 141 >3NA5-A nrPDB Length = 570 Score = 26.9 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 19/45 (42%) Query: 72 FDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLI 116 D I++ + I + +ND++ F+ LD +G I Sbjct: 257 VDPLGGSGIEYWKRIAEHYKLNLTLVNDQVDQTFRFMHLDKDGAI 301 >2Y3N-B nrPDB Length = 71 Score = 26.9 bits (58), Expect = 5.3, Method: Composition-based stats. Identities = 10/60 (16%), Positives = 25/60 (41%), Gaps = 15/60 (25%) Query: 109 DLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEE 168 DL+ +G+I+ +++ + + K +G+ + D N DG + ++ Sbjct: 8 DLNGDGVINMADVMILAQSFGKAIGNPG---------------VNEKADLNNDGVINSDD 52 >4YRV-B nrPDB Length = 307 Score = 26.9 bits (58), Expect = 5.4, Method: Composition-based stats. Identities = 6/42 (14%), Positives = 18/42 (42%) Query: 117 SYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDK 158 R++ + + ++ E+ D P +R ++ +D+ Sbjct: 238 DTARYFRMMKDWAEKRPNAMRALEELDVPPERWDEAMQELDE 279 >2KQ6-A nrPDB Length = 78 Score = 26.9 bits (58), Expect = 5.4, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 24/56 (42%), Gaps = 2/56 (3%) Query: 76 KNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKM 131 G ++F E L +G + ++ F YD D + ++ E ++ D + K Sbjct: 13 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKE 66 >2L5Y-A nrPDB Length = 150 Score = 26.5 bits (57), Expect = 6.5, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 22/44 (50%) Query: 133 GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRD 176 GS + E++ + + I MD +KDG + +EE E + D Sbjct: 1 GSHMASTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIRED 44 >4F52-A nrPDB Length = 282 Score = 26.5 bits (57), Expect = 6.5, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 21/43 (48%) Query: 117 SYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 S +E+ R D++ K + E EDT + + K + DK+ Sbjct: 10 SPEELARYCDSLLKKSSKNPEEAELEDTLNQVMEKFKKIEDKD 52 >1WLM-A nrPDB Length = 151 Score = 26.5 bits (57), Expect = 6.9, Method: Composition-based stats. Identities = 10/72 (13%), Positives = 27/72 (37%), Gaps = 3/72 (4%) Query: 101 LIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNK 160 L +F+ + + + S E + + + K+ + + V+ +F+ + Sbjct: 17 LEESFRKFAIHGDPKASGQE---MNGKNWAKLCKDCKVADGKAVTGTDVDIVFSKVKAKS 73 Query: 161 DGQLTLEEFCEG 172 + EEF + Sbjct: 74 ARVINYEEFKKA 85 >5NRM-B nrPDB Length = 66 Score = 26.5 bits (57), Expect = 7.3, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 23/62 (37%) Query: 73 DADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D D NG I+ +F + + + DL+ + I+ ++ + + M+ Sbjct: 4 DVDGNGSINSIDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSININDFAIMRMYLLGMI 63 Query: 133 GS 134 Sbjct: 64 TK 65 >5AHV-F nrPDB Length = 268 Score = 26.5 bits (57), Expect = 7.3, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 28/70 (40%), Gaps = 7/70 (10%) Query: 76 KNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSM 135 NG +++E++ +SV+ E + ++ L D S DE +I+ A + Sbjct: 123 NNGTFEYEEYVSLVSVSDPDEGYETILDLMSLQD-------SLDEFSQIIFASIQSERRN 175 Query: 136 VKLPEDEDTP 145 + P Sbjct: 176 TECKISALIP 185 >3RTR-A nrPDB Length = 368 Score = 26.5 bits (57), Expect = 7.3, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 21/43 (48%) Query: 117 SYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKN 159 S +E+ R D++ K + E EDT + + K + DK+ Sbjct: 10 SPEELARYCDSLLKKSSKNPEEAELEDTLNQVMEKFKKIEDKD 52 >3B97-A nrPDB Length = 433 Score = 26.5 bits (57), Expect = 7.3, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 35/90 (38%), Gaps = 3/90 (3%) Query: 70 NVFDADKNGYIDFKEFIC--ALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDA 127 +FD+ N ++ F + + A +L D D + + + V+ Sbjct: 9 EIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKG-VSKAVEH 67 Query: 128 IYKMVGSMVKLPEDEDTPEKRVNKIFNMMD 157 I K + + + T +++++K+ MD Sbjct: 68 INKTIAPALVSKKLNVTEQEKIDKLMIEMD 97 >5NRK-B nrPDB Length = 68 Score = 26.5 bits (57), Expect = 7.7, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 22/62 (35%) Query: 73 DADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 D D NG I+ +F + + + DL+ + I+ + + + M+ Sbjct: 4 DVDGNGSININDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSINSLDFAIMRMYLLGMI 63 Query: 133 GS 134 Sbjct: 64 TK 65 >1F6V-A nrPDB Length = 91 Score = 26.5 bits (57), Expect = 8.0, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 16/30 (53%), Gaps = 2/30 (6%) Query: 86 ICALSVTSRGEL--NDKLIWAFQLYDLDNN 113 + A++ +GE D L AF+ DLD + Sbjct: 55 LAAMTAHGKGERVNEDYLRQAFRELDLDVD 84 >6IML-A nrPDB Length = 419 Score = 26.1 bits (56), Expect = 8.2, Method: Composition-based stats. Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 5/56 (8%) Query: 24 KKELQQWYKGFFK----DCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDAD 75 KKEL+Q Y F +L++ Q I Q D S YVF+ F +D Sbjct: 184 KKELKQLY-LFIDVRVYLDGELYLHRKPLQWIAGQANAKTDSSELHFYVFDCFWSD 238 >4DUQ-A nrPDB Length = 98 Score = 26.1 bits (56), Expect = 9.0, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 23/55 (41%), Gaps = 7/55 (12%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 +S EM ++ + E E+ + K+ +D+N D Q+ +E+ Sbjct: 29 KLSKGEMKELLH-------KELPSFVGEKVDEEGLKKLMGSLDENSDQQVDFQEY 76 >1YP3-A nrPDB Length = 451 Score = 26.1 bits (56), Expect = 9.4, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 30/79 (37%), Gaps = 12/79 (15%) Query: 81 DFKEFICALSVTSRG------ELNDKLIWAFQLYDLDNNGL-ISYDEMLRIVDAIYKMVG 133 D+++FI A T +++K AF L +D G I + E + + Sbjct: 151 DYEKFIQAHRETDADITVAALPMDEKRATAFGLMKIDEEGRIIEFAE-----KPQGEQLQ 205 Query: 134 SMVKLPEDEDTPEKRVNKI 152 +M +KR ++ Sbjct: 206 AMKVDTTILGLDDKRAKEM 224 >4EME-A nrPDB Length = 571 Score = 26.1 bits (56), Expect = 9.8, Method: Composition-based stats. Identities = 7/25 (28%), Positives = 16/25 (64%), Gaps = 1/25 (4%) Query: 166 LEEFCEGSKRDPTIVSALSLYDGLV 190 EEF EG++ D ++ + +++G + Sbjct: 315 YEEFIEGARFD-NLLGSFCVFEGFI 338 >2OZ6-A nrPDB Length = 207 Score = 26.1 bits (56), Expect = 9.9, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 17/30 (56%) Query: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDT 144 I+ E+ RIV +MVG ++K E++ Sbjct: 164 KITRQEIGRIVGCSREMVGRVLKSLEEQGL 193 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.138 0.364 Lambda K H 0.267 0.0425 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,764,124 Number of Sequences: 36641 Number of extensions: 316334 Number of successful extensions: 4050 Number of sequences better than 10.0: 371 Number of HSP's better than 10.0 without gapping: 433 Number of HSP's successfully gapped in prelim test: 140 Number of HSP's that attempted gapping in prelim test: 1418 Number of HSP's gapped (non-prelim): 1409 length of query: 190 length of database: 10,336,785 effective HSP length: 92 effective length of query: 98 effective length of database: 6,965,813 effective search space: 682649674 effective search space used: 682649674 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 56 (26.1 bits)