BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q09024 (267 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6FEY-A nrPDB 505 e-144 5O5G-A nrPDB 48 4e-06 6IAA-A nrPDB 47 6e-06 3JXA-A nrPDB 47 6e-06 5Z5K-A nrPDB 46 1e-05 1TLK-A nrPDB 44 5e-05 3S97-C nrPDB 44 8e-05 6DLF-A nrPDB 42 4e-04 2WIM-A nrPDB 42 4e-04 5FTT-A nrPDB 38 0.005 3V2A-R nrPDB 36 0.015 5OYJ-C nrPDB 36 0.016 4V2A-A nrPDB 36 0.018 2EO9-A nrPDB 35 0.028 3V6B-R nrPDB 35 0.028 6A77-A nrPDB 35 0.045 1E07-A nrPDB 34 0.068 5OJ2-A nrPDB 33 0.099 3UTO-A nrPDB 33 0.12 1KOA-A nrPDB 33 0.12 4KC3-B nrPDB 33 0.17 3O3U-N nrPDB 32 0.20 2XY2-A nrPDB 32 0.26 6DLD-B nrPDB 32 0.26 3O4O-C nrPDB 30 0.96 2XOT-A nrPDB 30 1.1 5T89-X nrPDB 30 1.2 3K0W-A nrPDB 29 1.7 3BFO-A nrPDB 29 2.0 2VAJ-A nrPDB 29 2.2 6HEH-A nrPDB 29 2.3 1WWC-A nrPDB 28 3.1 4H1O-A nrPDB 28 3.3 3O2D-A nrPDB 28 3.5 4Q6I-C nrPDB 28 3.6 5IMK-A nrPDB 28 4.0 1WIO-A nrPDB 28 4.6 3JBW-A nrPDB 27 7.2 >6FEY-A nrPDB Length = 242 Score = 505 bits (1300), Expect = e-144, Method: Compositional matrix adjust. Identities = 242/242 (100%), Positives = 242/242 (100%) Query: 26 RAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGS 85 RAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGS Sbjct: 1 RAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGS 60 Query: 86 QVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGS 145 QVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGS Sbjct: 61 QVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGS 120 Query: 146 KTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI 205 KTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI Sbjct: 121 KTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI 180 Query: 206 TWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNE 265 TWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNE Sbjct: 181 TWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNE 240 Query: 266 ED 267 ED Sbjct: 241 ED 242 >5O5G-A nrPDB Length = 385 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 46/196 (23%), Positives = 72/196 (36%), Gaps = 37/196 (18%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVV--GHLPRSELDDLDSNQVAEEAPSAIVRVR 122 P+ L + E CE G VP+++W G LP+S + D Sbjct: 206 PSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRD---------------- 249 Query: 123 SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKT 182 DH L + R T G GS T A +V +S T + P + + Sbjct: 250 -----DHTL-KIRKVT-AGDMGSYTCVAENMVGKAEAS-----ATLTVQEPPHFVVKPRD 297 Query: 183 HLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGH-------RHRVLANGDLLISEIK 235 + +G + C P+ I W ++ ++ + R V GDL I+ ++ Sbjct: 298 QVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQ 357 Query: 236 WEDMGNYKCIARNVVG 251 D+G Y C NV G Sbjct: 358 RSDVGYYICQTLNVAG 373 Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Query: 192 QLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVG 251 + C P + W ++ + + R+ + + L I ++ DMG+Y C+A N+VG Sbjct: 218 EFKCEARGDPVPTVRWRKDDGE--LPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVG 275 Query: 252 KDTA 255 K A Sbjct: 276 KAEA 279 Score = 34.3 bits (77), Expect = 0.062, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 11/89 (12%) Query: 174 PRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNN-----ENKEIVQGHRHRVLANGD 228 PRI+ + G L C+ RP I W +K+ + HR +L +G Sbjct: 6 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM-LLPSGS 64 Query: 229 LLISEI-----KWEDMGNYKCIARNVVGK 252 L I D G Y C+ARN +G+ Sbjct: 65 LFFLRIVHGRKSRPDEGVYVCVARNYLGE 93 Score = 31.2 bits (69), Expect = 0.53, Method: Compositional matrix adjust. Identities = 48/198 (24%), Positives = 70/198 (35%), Gaps = 33/198 (16%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSA------I 118 P+ L + G + C+ G P+I+W G R E D D PS I Sbjct: 12 PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGG-ERVETDKDDPRSHRMLLPSGSLFFLRI 70 Query: 119 VRVRSSHIIDHVLSEARTYTCVGRT--GSKTIY-ASTVVHPPRSS-RLTPEKTYPGAQKP 174 V R S + V Y CV R G + AS V R R P +P Sbjct: 71 VHGRKSRPDEGV------YVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEP 124 Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEI 234 ++ + P R H P I+W + + + G L+I+ Sbjct: 125 AVMECQ-------------PPRGHPEP--TISW-KKDGSPLDDKDERITIRGGKLMITYT 168 Query: 235 KWEDMGNYKCIARNVVGK 252 + D G Y C+ N+VG+ Sbjct: 169 RKSDAGKYVCVGTNMVGE 186 >6IAA-A nrPDB Length = 859 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 40/187 (21%), Positives = 65/187 (34%), Gaps = 41/187 (21%) Query: 76 IEIVCEMMGSQVPSIQWVV--GHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSE 133 +E C++ G P+++W LPR D D +R++ + D Sbjct: 232 VEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDD---------YTLRIKKTMSTDE---- 278 Query: 134 ARTYTCVG--RTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNI 191 TY C+ R G A+ V P P+ + + + G + Sbjct: 279 -GTYMCIAENRVGKMEASATLTVRAP----------------PQFVVRPRDQIVAQGRTV 321 Query: 192 QLPCRVHARPRAEITWLNNENKEIV-------QGHRHRVLANGDLLISEIKWEDMGNYKC 244 PC P+ + W ++ ++ R V GDL I+ I+ D G Y C Sbjct: 322 TFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYIC 381 Query: 245 IARNVVG 251 A V G Sbjct: 382 QALTVAG 388 Score = 34.7 bits (78), Expect = 0.043, Method: Compositional matrix adjust. Identities = 39/183 (21%), Positives = 63/183 (34%), Gaps = 13/183 (7%) Query: 71 ADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHV 130 A G T+ CE G+ P++ W + L NQ + V I ++ Sbjct: 316 AQGRTVTFPCETKGNPQPAVFW----QKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNI 371 Query: 131 L-SEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGS 189 S+A Y C T + +I A ++L P I+ + Sbjct: 372 QRSDAGYYICQALTVAGSILAK--------AQLEVTDVLTDRPPPIILQGPANQTLAVDG 423 Query: 190 NIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNV 249 L C+ P I+WL + R + G L I ++ D G Y C+A + Sbjct: 424 TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSS 483 Query: 250 VGK 252 G+ Sbjct: 484 SGE 486 Score = 34.7 bits (78), Expect = 0.049, Method: Compositional matrix adjust. Identities = 50/219 (22%), Positives = 90/219 (41%), Gaps = 25/219 (11%) Query: 44 EEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVV-GHLPRSEL 102 ++++P +R + D+ P+ + + G + C+ G P+I+W G ++ Sbjct: 6 DDKRPHSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDK 65 Query: 103 DDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRT---GSKTIYASTVVHPPRS 159 DD S+++ + ++ +R H E +Y CV R + + AS V R Sbjct: 66 DDPRSHRMLLPS-GSLFFLRIVHGRRSKPDEG-SYVCVARNYLGEAVSRNASLEVALLRD 123 Query: 160 S-RLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQG 218 R P A +P I+ + P R H P I W ++K + Sbjct: 124 DFRQNPTDVVVAAGEPAILECQ-------------PPRGHPEP--TIYW--KKDKVRIDD 166 Query: 219 HRHRV-LANGDLLISEIKWEDMGNYKCIARNVVGKDTAD 256 R+ + G L+IS + D G Y C+ N+VG+ +D Sbjct: 167 KEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSD 205 Score = 34.3 bits (77), Expect = 0.057, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 2/62 (3%) Query: 191 IQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVV 250 ++ C+V P+ + W ++ ++ +G R+ + + L I + D G Y CIA N V Sbjct: 232 VEFRCQVQGDPQPTVRW-KKDDADLPRG-RYDIKDDYTLRIKKTMSTDEGTYMCIAENRV 289 Query: 251 GK 252 GK Sbjct: 290 GK 291 >3JXA-A nrPDB Length = 383 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 8/126 (6%) Query: 132 SEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRI-IYTEKTHLDLMGSN 190 S+ YTCV + T+ V+ PP L + G +P+I + +T G+ Sbjct: 166 SDVGNYTCVV---TNTVTNHKVLGPPTPLILRNDGVM-GEYEPKIEVQFPETVPAEKGTT 221 Query: 191 IQLPCRVHARPRAEITWLNNENKEIV-QGHRHRVLANGDLLISEIKWEDMGNYKCIARNV 249 ++L C P I W + K I + RH+ +NG L I + ED G+Y+C+A N Sbjct: 222 VKLECFALGNPVPTILWRRADGKPIARKARRHK--SNGILEIPNFQQEDAGSYECVAENS 279 Query: 250 VGKDTA 255 GK+ A Sbjct: 280 RGKNVA 285 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 3/70 (4%) Query: 184 LDLMGSNIQLPCRVHARPRAEITW-LNNENKEIVQGHRHRVLANGDLLISEI-KWEDMGN 241 LD ++L C V P+ I W LN + +I R+ V+ +G LLI+ K +D G Sbjct: 18 LDSEEKKVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVV-DGSLLINNPNKTQDAGT 76 Query: 242 YKCIARNVVG 251 Y+CIA N G Sbjct: 77 YQCIATNSFG 86 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 44/198 (22%), Positives = 79/198 (39%), Gaps = 39/198 (19%) Query: 58 LKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSA 117 ++F +T P + G T+++ C +G+ VP+I W D +A +A Sbjct: 208 VQFPETVPAE----KGTTVKLECFALGNPVPTILW----------RRADGKPIARKA--- 250 Query: 118 IVRVRSSHII---DHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKP 174 R +S+ I+ + +A +Y CV R + + AQ Sbjct: 251 -RRHKSNGILEIPNFQQEDAGSYECVAENS-------------RGKNVAKGQLTFYAQPN 296 Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRV-LANGDLLISE 233 + H+ M ++ C+ + RP+ WL N + + R R+ + G L I+ Sbjct: 297 WVQIINDIHV-AMEESVFWECKANGRPKPTYRWLKNGDPLLT---RDRIQIEQGTLNITI 352 Query: 234 IKWEDMGNYKCIARNVVG 251 + D G Y+C+A N G Sbjct: 353 VNLSDAGMYQCVAENKHG 370 Score = 32.7 bits (73), Expect = 0.15, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 22/44 (50%) Query: 207 WLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVV 250 W+ NE R G+L I++++ D+GNY C+ N V Sbjct: 136 WIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTV 179 >5Z5K-A nrPDB Length = 380 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 27/179 (15%) Query: 73 GATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLS 132 G T+ + CE++G +P+I W + + D N + ++ ++ + I Sbjct: 116 GDTVLLKCEVIGDPMPTIHW--------QKNQQDLNPIPGDSRVVVLPSGALQISRLQPG 167 Query: 133 EARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEK-----TYPGAQKPRIIYTEKTH-LDL 186 ++ Y C R P S+R E + PG + ++ + + Sbjct: 168 DSGVYRCSARN-------------PASTRTGNEAEVRILSDPGLHRQLYFLQRPSNVIAI 214 Query: 187 MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCI 245 G + L C V P TWL E ++ ++ +L +LLIS + +D G Y C+ Sbjct: 215 EGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGTYTCV 273 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 43/190 (22%), Positives = 79/190 (41%), Gaps = 31/190 (16%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P+ + +G + C + G PS W+ G E+ L S + + S ++ S Sbjct: 208 PSNVIAIEGKDAVLECCVSGYPPPSFTWLRGE----EVIQLRSKKYSLLGGSNLL---IS 260 Query: 125 HIIDHVLSEARTYTCVGRTGSKTIYAS---TVVHPPRSSRLTPEKTYPGAQKPRIIYTEK 181 ++ D ++ TYTCV ++ I AS TV+ PP P +Y + Sbjct: 261 NVTD---DDSGTYTCVVTYKNENISASAELTVLVPPWF-----------LNHPSNLYAYE 306 Query: 182 THLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGN 241 + +I+ C V +P + W+ N + ++ +++ +L I + D G Sbjct: 307 SM------DIEFECAVSGKPVPTVNWMKNGDV-VIPSDYFQIVGGSNLRILGVVKSDEGF 359 Query: 242 YKCIARNVVG 251 Y+C+A N G Sbjct: 360 YQCVAENEAG 369 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 2/84 (2%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNEN--KEIVQGHRHRVLANGDLLIS 232 R + ++ MG + L C V P I W N+ I R VL +G L IS Sbjct: 103 RFLSQTESITAFMGDTVLLKCEVIGDPMPTIHWQKNQQDLNPIPGDSRVVVLPSGALQIS 162 Query: 233 EIKWEDMGNYKCIARNVVGKDTAD 256 ++ D G Y+C ARN T + Sbjct: 163 RLQPGDSGVYRCSARNPASTRTGN 186 >1TLK-A nrPDB Length = 154 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 11/93 (11%) Query: 172 QKPRII-YTEKTHLDL---MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVL--- 224 +KP + Y KT LD+ GS + C+V P E+ W ++N V+ RH + Sbjct: 36 EKPHVKPYFTKTILDMDVVEGSAARFDCKVEGYPDPEVMWFKDDNP--VKESRHFQIDYD 93 Query: 225 --ANGDLLISEIKWEDMGNYKCIARNVVGKDTA 255 N L ISE+ +D Y C A N +G+ T Sbjct: 94 EEGNCSLTISEVCGDDDAKYTCKAVNSLGEATC 126 >3S97-C nrPDB Length = 201 Score = 43.5 bits (101), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 48/176 (27%), Positives = 69/176 (39%), Gaps = 23/176 (13%) Query: 96 HLPRSELDDLDSNQVAEEAPSAIV----RVRSS-----HIIDHVLSEARTYTCVGRTGS- 145 H P DDL + E P I R S +I + S+ Y+C + S Sbjct: 35 HFP----DDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSI 90 Query: 146 -KTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAE 204 K++++ + P R T K YP I+ K LMG N+ L C P + Sbjct: 91 TKSVFSKFIPLIPIPERTT--KPYPA----DIVVQFKDVYALMGQNVTLECFALGNPVPD 144 Query: 205 ITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVY 260 I W + E + + L I I+ ED G Y+C A N+ GKD +Y Sbjct: 145 IRW--RKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIY 198 >6DLF-A nrPDB Length = 306 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 10/123 (8%) Query: 142 RTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARP 201 ++G AS V P R+ YP P I + T + + G L C A P Sbjct: 173 QSGDYECSASNDVAAPVVRRVKVTVNYP----PYISEAKGTGVPV-GQKGTLQCEASAVP 227 Query: 202 RAEITWLNNENKEIVQGHRHRVLAN----GDLLISEIKWEDMGNYKCIARNVVGKDTADT 257 AE W ++ K +++G + + N L+ + D GNY C+A N +G A Sbjct: 228 SAEFQWYKDD-KRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASI 286 Query: 258 FVY 260 ++ Sbjct: 287 MLF 289 Score = 30.4 bits (67), Expect = 0.73, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 5/64 (7%) Query: 188 GSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIAR 247 G+NI L C RP +TW + K + V + L I I E G+Y+C A Sbjct: 128 GNNISLTCIATGRPEPTVTWRHISPKAV-----GFVSEDEYLEIQGITREQSGDYECSAS 182 Query: 248 NVVG 251 N V Sbjct: 183 NDVA 186 >2WIM-A nrPDB Length = 291 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 35/202 (17%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P + +Q + A E+VC + S P++ W+ + E+ + N+ A ++ + Sbjct: 107 PQEFKQGEDA--EVVCRVSSSPAPAVSWLYHN---EEVTTISDNRFA------MLANNNL 155 Query: 125 HIIDHVLSEARTYTCVGRTGSK--TIYASTVV---HPPRSSRLTPEKTYPGAQKPRIIYT 179 I++ S+ Y C GR ++ + +V PP S P+K++ + Sbjct: 156 QILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAIS--MPQKSFNATAE------ 207 Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVL--ANGDLLISEIKWE 237 G + CR P I+W N ++++ + +L +N +L + I Sbjct: 208 -------RGEEMTFSCRASGSPEPAISWFRN--GKLIEENEKYILKGSNTELTVRNIINS 258 Query: 238 DMGNYKCIARNVVGKDTADTFV 259 D G Y C A N G+D F+ Sbjct: 259 DGGPYVCRATNKAGEDEKQAFL 280 Score = 29.3 bits (64), Expect = 2.0, Method: Compositional matrix adjust. Identities = 21/79 (26%), Positives = 32/79 (40%), Gaps = 4/79 (5%) Query: 187 MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG---DLLISEIKWEDMGNYK 243 +G + C P + I W N + ++I+ R V G L I ED G Y+ Sbjct: 18 VGESKFFTCTAIGEPES-IDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYR 76 Query: 244 CIARNVVGKDTADTFVYPV 262 C A + G+ T V + Sbjct: 77 CQATDAKGQTQEATVVLEI 95 >5FTT-A nrPDB Length = 285 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 2/64 (3%) Query: 191 IQLPCRV-HARPRAEITWLNNENK-EIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARN 248 I L CR P AE+ WL NE + Q A+ +L+I + + D GNY C+A N Sbjct: 143 IVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAAN 202 Query: 249 VVGK 252 +V K Sbjct: 203 IVAK 206 >3V2A-R nrPDB Length = 772 Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust. Identities = 38/142 (26%), Positives = 55/142 (38%), Gaps = 15/142 (10%) Query: 113 EAPSAIVRVRSSHIIDHVL-SEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGA 171 ++ S + + S+ ID V S+ YTC +G T ST V EK + Sbjct: 280 QSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVR-------VHEKPFVAF 332 Query: 172 QKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLI 231 E T +G +++P + P EI W N I H + A L I Sbjct: 333 GSGMESLVEAT----VGERVRIPAKYLGYPPPEIKWYKNG---IPLESNHTIKAGHVLTI 385 Query: 232 SEIKWEDMGNYKCIARNVVGKD 253 E+ D GNY I N + K+ Sbjct: 386 MEVSERDTGNYTVILTNPISKE 407 Score = 34.7 bits (78), Expect = 0.049, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 4/74 (5%) Query: 187 MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGD--LLISEIKWEDMGNYKC 244 +G +I++ C P +I W +N+ +V+ VL +G+ L I ++ ED G Y C Sbjct: 680 IGESIEVSCTASGNPPPQIMWFK-DNETLVE-DSGIVLKDGNRNLTIRRVRKEDEGLYTC 737 Query: 245 IARNVVGKDTADTF 258 A +V+G + F Sbjct: 738 QACSVLGCAKVEAF 751 >5OYJ-C nrPDB Length = 234 Score = 36.2 bits (82), Expect = 0.016, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 6/88 (6%) Query: 169 PGAQKPRIIY---TEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLA 225 P A+KP + + E +G +++P + P EI W N I H + A Sbjct: 2 PLAEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYKNG---IPLESNHTIKA 58 Query: 226 NGDLLISEIKWEDMGNYKCIARNVVGKD 253 L I E+ D GNY I N + K+ Sbjct: 59 GHVLTIMEVSERDTGNYTVILTNPISKE 86 >4V2A-A nrPDB Length = 303 Score = 35.8 bits (81), Expect = 0.018, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 21/84 (25%) Query: 190 NIQLPCRV-HARPRAEITWLNNE---------NKEIVQGHRHRVLANGDLLISEIKWEDM 239 I LPCR P AE+ WL NE N I + H L++ + + D Sbjct: 165 GIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREH--------SLVVRQARLADT 216 Query: 240 GNYKCIARNVVGK---DTADTFVY 260 NY C+A+N+V + +A VY Sbjct: 217 ANYTCVAKNIVARRRSASAAVIVY 240 >2EO9-A nrPDB Length = 118 Score = 35.4 bits (80), Expect = 0.028, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 26/67 (38%) Query: 193 LPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGK 252 L C P I W + Q R + L NG L I K D G Y CIA G+ Sbjct: 28 LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGE 87 Query: 253 DTADTFV 259 T ++ Sbjct: 88 ATWSAYI 94 >3V6B-R nrPDB Length = 424 Score = 35.4 bits (80), Expect = 0.028, Method: Compositional matrix adjust. Identities = 38/142 (26%), Positives = 55/142 (38%), Gaps = 15/142 (10%) Query: 113 EAPSAIVRVRSSHIIDHVL-SEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGA 171 ++ S + + S+ ID V S+ YTC +G T ST V EK + Sbjct: 150 QSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVR-------VHEKPFVAF 202 Query: 172 QKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLI 231 E T +G +++P + P EI W N I H + A L I Sbjct: 203 GSGMESLVEAT----VGERVRIPAKYLGYPPPEIKWYKNG---IPLESNHTIKAGHVLTI 255 Query: 232 SEIKWEDMGNYKCIARNVVGKD 253 E+ D GNY I N + K+ Sbjct: 256 MEVSERDTGNYTVILTNPISKE 277 >6A77-A nrPDB Length = 91 Score = 34.7 bits (78), Expect = 0.045, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 26/67 (38%) Query: 193 LPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGK 252 L C P I W + Q R + L NG L I K D G Y CIA G+ Sbjct: 22 LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGE 81 Query: 253 DTADTFV 259 T ++ Sbjct: 82 ATWSAYI 88 >1E07-A nrPDB Length = 642 Score = 33.9 bits (76), Expect = 0.068, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 9/61 (14%) Query: 188 GSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIAR 247 G N+ L C + P A+ +WL + N +Q H +L IS I ++ G Y C A Sbjct: 396 GVNLSLSCHAASNPPAQYSWLIDGN---IQQHTQ------ELFISNITEKNSGLYTCQAN 446 Query: 248 N 248 N Sbjct: 447 N 447 Score = 32.3 bits (72), Expect = 0.20, Method: Compositional matrix adjust. Identities = 43/179 (24%), Positives = 65/179 (36%), Gaps = 34/179 (18%) Query: 72 DGATIEIVCEMMGSQVPSIQWVVGH-LPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHV 130 D + CE + WV G LP S L + R+ + + Sbjct: 481 DKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGN------------RTLTLFNVT 528 Query: 131 LSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSN 190 ++AR Y C G S V RS +T + Y G P I + ++L G+N Sbjct: 529 RNDARAYVC-GIQNS--------VSANRSDPVTLDVLY-GPDTPIISPPDSSYLS--GAN 576 Query: 191 IQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNV 249 + L C + P + +W N I Q H L I++I + G Y C N+ Sbjct: 577 LNLSCHSASNPSPQYSWRIN---GIPQQHTQV------LFIAKITPNNNGTYACFVSNL 626 Score = 30.8 bits (68), Expect = 0.68, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 9/61 (14%) Query: 188 GSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIAR 247 G N+ L C + P A+ +W V G + + +L I I + G+Y C A Sbjct: 218 GENLNLSCHAASNPPAQYSWF-------VNGTFQQ--STQELFIPNITVNNSGSYTCQAH 268 Query: 248 N 248 N Sbjct: 269 N 269 >5OJ2-A nrPDB Length = 910 Score = 33.5 bits (75), Expect = 0.099, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 13/75 (17%) Query: 188 GSNIQLPCRV-HARPRAEITWLNNEN----KEIVQGHRHRVLANGDLLISEIKWEDMGNY 242 G N+ + C + P+ E+ W ++ +VQG G+L I I+ ED G Y Sbjct: 237 GDNVTMQCSLTGGDPQPEVLWSHSPGPLPPNSLVQG--------GNLTIWRIRVEDSGYY 288 Query: 243 KCIARNVVGKDTADT 257 C A N VG T Sbjct: 289 NCTAINNVGNPAKKT 303 Score = 32.0 bits (71), Expect = 0.31, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 1/73 (1%) Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWED 238 +E+ + G + L C V PR ++ W + VL N L I +I+ Sbjct: 26 SERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVL-NETLRIEKIQRLQ 84 Query: 239 MGNYKCIARNVVG 251 G Y C A N VG Sbjct: 85 GGRYYCKAENGVG 97 Score = 31.6 bits (70), Expect = 0.38, Method: Compositional matrix adjust. Identities = 32/123 (26%), Positives = 46/123 (37%), Gaps = 9/123 (7%) Query: 123 SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKT 182 S IID S+ TY CV I +V S + P + P Q I E Sbjct: 381 SLEIIDLRFSDYGTYLCVATFQGAPIPDLSVEVNISSETVPPTISVPKGQS-TITVRE-- 437 Query: 183 HLDLMGSNIQLPCRVHARPRAEITWLN-NENKEIVQGHRHRVLANGDLLISEIKWEDMGN 241 GS +L C V +P+ I W ++ + G +G L + + + G Sbjct: 438 -----GSRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGT 492 Query: 242 YKC 244 YKC Sbjct: 493 YKC 495 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 15/69 (21%), Positives = 33/69 (47%), Gaps = 9/69 (13%) Query: 187 MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGD---------LLISEIKWE 237 +G +++L C V A P+ ++ + +N + + ++ D L I ++++ Sbjct: 331 LGQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTCSLEIIDLRFS 390 Query: 238 DMGNYKCIA 246 D G Y C+A Sbjct: 391 DYGTYLCVA 399 >3UTO-A nrPDB Length = 573 Score = 33.1 bits (74), Expect = 0.12, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 4/75 (5%) Query: 188 GSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGD---LLISEIKWEDMGNYKC 244 G + CRV A +TW + +++E+ Q ++ NG+ L I+ +K +D G Y Sbjct: 497 GQSANFYCRVIASSPPVVTW-HKDDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTV 555 Query: 245 IARNVVGKDTADTFV 259 A+N G F+ Sbjct: 556 RAKNSYGTKEEIVFL 570 >1KOA-A nrPDB Length = 491 Score = 33.1 bits (74), Expect = 0.12, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 4/75 (5%) Query: 188 GSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGD---LLISEIKWEDMGNYKC 244 G + CRV A +TW + +++E+ Q ++ NG+ L I+ +K +D G Y Sbjct: 391 GQSANFYCRVIASSPPVVTW-HKDDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTV 449 Query: 245 IARNVVGKDTADTFV 259 A+N G F+ Sbjct: 450 RAKNSYGTKEEIVFL 464 >4KC3-B nrPDB Length = 309 Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust. Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 23/120 (19%) Query: 131 LSEARTYTCVGR--TGSKTIYASTVVHPPRSSRLTPE----KTYPGAQKPRIIYTEKTHL 184 ++++ YTC+ R T ++T YA+ ++ +S P+ T G++K IY + Sbjct: 61 VADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPT--I 118 Query: 185 DLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKC 244 DL A + W +N + +QG R+R L+I + ED G+Y C Sbjct: 119 DLYNWT------------APLEWF--KNCQALQGSRYRA-HKSFLVIDNVMTEDAGDYTC 163 Score = 31.2 bits (69), Expect = 0.55, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 2/56 (3%) Query: 195 CRVHARPRAEITWLNNE-NKEIVQGHRHRVLANGDLL-ISEIKWEDMGNYKCIARN 248 C +P + W ++ NK I R+RV A+G LL D G Y CI R+ Sbjct: 18 CPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRS 73 >3O3U-N nrPDB Length = 581 Score = 32.3 bits (72), Expect = 0.20, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 21/37 (56%) Query: 222 RVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTF 258 RVL NG L + + +D G ++C A N GK+T + Sbjct: 427 RVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNY 463 >2XY2-A nrPDB Length = 189 Score = 32.0 bits (71), Expect = 0.26, Method: Compositional matrix adjust. Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 1/61 (1%) Query: 188 GSNIQLPCRVHARPRAEITWL-NNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIA 246 G + ++ CRV + P ++WL +NE + +R +LAN +L I I D G Y+C Sbjct: 111 GEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEG 170 Query: 247 R 247 R Sbjct: 171 R 171 Score = 29.3 bits (64), Expect = 2.0, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 33/82 (40%), Gaps = 4/82 (4%) Query: 187 MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG---DLLISEIKWEDMGNYK 243 +G + C P + I W N + ++I+ R V G L I ED G Y+ Sbjct: 16 VGESKFFTCTAIGEPES-IDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYR 74 Query: 244 CIARNVVGKDTADTFVYPVLNE 265 C A + G+ T V + + Sbjct: 75 CQATDAKGQTQEATVVLEIYQK 96 >6DLD-B nrPDB Length = 304 Score = 32.0 bits (71), Expect = 0.26, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 195 CRVHARPRAEITWLNNENKEIVQGHRHRVLANGD----LLISEIKWEDMGNYKCIARNVV 250 C P W E K++ G + ++ N L ++ + E GNY C+A N + Sbjct: 219 CEGAGVPPPAFEWYKGE-KKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKL 277 Query: 251 GKDTA 255 G A Sbjct: 278 GTTNA 282 Score = 28.1 bits (61), Expect = 3.9, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 27/69 (39%), Gaps = 18/69 (26%) Query: 188 GSNIQLPCRVHARPRAEITWLNNENKEIVQGHRH-----RVLANGDLL-ISEIKWEDMGN 241 G+N+ L C +P I+W RH + NG L I I + G Sbjct: 127 GTNVTLTCLATGKPEPSISW------------RHISPSAKPFENGQYLDIYGITRDQAGE 174 Query: 242 YKCIARNVV 250 Y+C A N V Sbjct: 175 YECSAENDV 183 >3O4O-C nrPDB Length = 339 Score = 30.0 bits (66), Expect = 0.96, Method: Compositional matrix adjust. Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 201 PRAEITWLNNENKEIVQGHRH-RVLA-NGDLLISEIKWEDMGNYKCIARN 248 PR +TW N++ V G R+ A +G L + ED G Y C RN Sbjct: 53 PRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRN 102 Score = 26.9 bits (58), Expect = 9.6, Method: Compositional matrix adjust. Identities = 25/105 (23%), Positives = 40/105 (38%), Gaps = 19/105 (18%) Query: 174 PRIIYTEKTHLDLMGSNIQLPCRVH---ARPRAEITWLNNENKEI---------VQGHRH 221 P II KT +GS + +PC+V P + W + I +G R Sbjct: 227 PVIISPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQ 286 Query: 222 RVLANGD------LLISEIKWEDMG-NYKCIARNVVGKDTADTFV 259 N + L+ + ED+ ++KC+ N + T T V Sbjct: 287 EYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTV 331 >2XOT-A nrPDB Length = 361 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 17/62 (27%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 187 MGSNIQLPCRVHARPRAEITWLNNENKEIV-QGHRHRV-LANGDLLISEIKWEDMGNYKC 244 +G + + C + ++ W++ N++++ QG V + NGDL +++ ED G Y C Sbjct: 260 LGDTLTIRCDTKQQGMTKV-WVSPSNEQVLSQGSNGSVSVRNGDLFFKKVQVEDGGVYTC 318 Query: 245 IA 246 A Sbjct: 319 YA 320 >5T89-X nrPDB Length = 646 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 14/74 (18%) Query: 188 GSNIQLPCRVHARPRAEITWL-----NN-------ENKEIVQGHRHRVLANGDLLISEIK 235 G +++L C V+ ++TW+ NN +++ H + N L I + Sbjct: 544 GEDLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSISKQKMAITKEHSITLN--LTIMNVS 601 Query: 236 WEDMGNYKCIARNV 249 +D G Y C ARNV Sbjct: 602 LQDSGTYACRARNV 615 >3K0W-A nrPDB Length = 218 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 18/34 (52%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLP 98 PT + G+T+ + C +GS +P QW LP Sbjct: 125 PTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELP 158 >3BFO-A nrPDB Length = 91 Score = 29.3 bits (64), Expect = 2.0, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 18/34 (52%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLP 98 PT + G+T+ + C +GS +P QW LP Sbjct: 10 PTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELP 43 >2VAJ-A nrPDB Length = 93 Score = 28.9 bits (63), Expect = 2.2, Method: Compositional matrix adjust. Identities = 21/79 (26%), Positives = 32/79 (40%), Gaps = 4/79 (5%) Query: 187 MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG---DLLISEIKWEDMGNYK 243 +G + C P + I W N + ++I+ R V G L I ED G Y+ Sbjct: 14 VGESKFFTCTAIGEPES-IDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYR 72 Query: 244 CIARNVVGKDTADTFVYPV 262 C A + G+ T V + Sbjct: 73 CQATDAKGQTQEATVVLEI 91 >6HEH-A nrPDB Length = 382 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 11/82 (13%) Query: 164 PEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHA------RPRAEITWLNNENKEIVQ 217 PEK + + P+IIY ++ + Q+P R+HA + A W I Sbjct: 232 PEKIHNKLEFPQIIYMDRYMYGSGSGSRQVPYRLHAVLVHEGQANAGHYW-----AYIYN 286 Query: 218 GHRHRVLANGDLLISEIKWEDM 239 R L D+ ++E WE++ Sbjct: 287 QPRQSWLKYNDISVTESSWEEV 308 >1WWC-A nrPDB Length = 118 Score = 28.5 bits (62), Expect = 3.1, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 9/84 (10%) Query: 174 PRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNN-----ENKEI-VQGHRHRVLANG 227 PR++ E+ L L I+ R P + WL+N E+K I V+ ++ ++ G Sbjct: 9 PRVVSLEEPELRLEHC-IEFVVR--GNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEG 65 Query: 228 DLLISEIKWEDMGNYKCIARNVVG 251 LL ++ + GNY IA+N +G Sbjct: 66 CLLFNKPTHYNNGNYTLIAKNPLG 89 >4H1O-A nrPDB Length = 560 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Query: 55 ADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEA 114 A+ +++ +L++ +G IE+ + + S +W GHL E + L + + + Sbjct: 96 AELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEK--GKH 153 Query: 115 PSAIVRVRSSHIIDHVLS 132 S +VR SH D VLS Sbjct: 154 GSFLVRESQSHPGDFVLS 171 >3O2D-A nrPDB Length = 188 Score = 28.5 bits (62), Expect = 3.5, Method: Compositional matrix adjust. Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 7/93 (7%) Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG-----DLLISEI 234 +K L G ++L C + + W N+ +I+ G++ L G D S Sbjct: 1 KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKIL-GNQGSFLTKGPSKLNDRADSRR 59 Query: 235 KWEDMGNYKCIARNVVGKDTADTFVYPVLNEED 267 D GN+ I +N+ +D +DT++ V ++++ Sbjct: 60 SLWDQGNFPLIIKNLKIED-SDTYICEVEDQKE 91 >4Q6I-C nrPDB Length = 208 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 7/93 (7%) Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG-----DLLISEI 234 +K L G ++L C + + W N+ +I+ G++ L G D S Sbjct: 26 KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKIL-GNQGSFLTKGPSKLNDRADSRR 84 Query: 235 KWEDMGNYKCIARNVVGKDTADTFVYPVLNEED 267 D GN+ I +N+ +D +DT++ V ++++ Sbjct: 85 SLWDQGNFPLIIKNLKIED-SDTYICEVEDQKE 116 >5IMK-A nrPDB Length = 220 Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 26/68 (38%), Gaps = 7/68 (10%) Query: 188 GSNIQLPCRVHARPRAEITWLNNE--NKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCI 245 G I L C+ P W + N+E + +V LL D G+Y C Sbjct: 146 GMRISLQCQARGSPPISYIWYKQQTNNQEPI-----KVATLSTLLFKPAVIADSGSYFCT 200 Query: 246 ARNVVGKD 253 A+ VG + Sbjct: 201 AKGQVGSE 208 >1WIO-A nrPDB Length = 363 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 7/93 (7%) Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG-----DLLISEI 234 +K L G ++L C + + W N+ +I+ G++ L G D S Sbjct: 1 KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKIL-GNQGSFLTKGPSKLNDRADSRR 59 Query: 235 KWEDMGNYKCIARNVVGKDTADTFVYPVLNEED 267 D GN+ I +N+ +D +DT++ V ++++ Sbjct: 60 SLWDQGNFPLIIKNLKIED-SDTYICEVEDQKE 91 >3JBW-A nrPDB Length = 764 Score = 27.3 bits (59), Expect = 7.2, Method: Compositional matrix adjust. Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 99 RSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTC 139 R + D L + + E P+ ++R + + DH+LS+ C Sbjct: 4 RCQRDHLSTKLIPTEVPADLIRAVTCQVCDHLLSDPVQSPC 44 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6FEY-A nrPDB 358 1e-99 5O5G-A nrPDB 170 4e-43 5Z5K-A nrPDB 170 7e-43 6IAA-A nrPDB 161 2e-40 3S97-C nrPDB 155 2e-38 2WIM-A nrPDB 153 7e-38 3JXA-A nrPDB 141 3e-34 6DLF-A nrPDB 126 6e-30 1TLK-A nrPDB 93 1e-19 Sequences not found previously or not previously below threshold: 1QZ1-A nrPDB 101 4e-22 6DLD-B nrPDB 91 4e-19 3V2A-R nrPDB 77 6e-15 5OJ2-A nrPDB 71 4e-13 3V6B-R nrPDB 70 1e-12 1EPF-A nrPDB 68 3e-12 6A77-A nrPDB 68 3e-12 2XY2-A nrPDB 68 5e-12 2EO9-A nrPDB 67 6e-12 3UTO-A nrPDB 65 4e-11 1KOA-A nrPDB 65 4e-11 1U2H-A nrPDB 60 1e-09 1E07-A nrPDB 59 2e-09 5T89-X nrPDB 58 3e-09 3K0W-A nrPDB 58 3e-09 5OYJ-C nrPDB 55 3e-08 4KC3-B nrPDB 55 5e-08 5VI4-B nrPDB 50 1e-06 4PBW-B nrPDB 50 1e-06 4PBV-A nrPDB 50 1e-06 5FTT-A nrPDB 49 2e-06 5IMK-A nrPDB 49 3e-06 2VAJ-A nrPDB 49 3e-06 3BFO-A nrPDB 46 1e-05 1OLZ-A nrPDB 46 2e-05 4FOM-A nrPDB 45 3e-05 3O4O-C nrPDB 45 5e-05 2IFG-A nrPDB 43 2e-04 3KHO-B nrPDB 43 2e-04 4V2A-A nrPDB 42 2e-04 1WWC-A nrPDB 41 4e-04 1FSK-B nrPDB 41 5e-04 4MYW-B nrPDB 41 6e-04 2L7J-A nrPDB 41 7e-04 4LLY-B nrPDB 40 9e-04 4DEP-B nrPDB 40 0.001 5MO9-X nrPDB 40 0.002 1HCF-X nrPDB 40 0.002 1CT8-A nrPDB 39 0.002 2NCM-A nrPDB 39 0.002 4BSJ-A nrPDB 39 0.002 4AIZ-B nrPDB 39 0.003 1HNG-A nrPDB 38 0.003 1WEJ-L nrPDB 38 0.004 5VF3-Z nrPDB 38 0.004 3O3U-N nrPDB 38 0.004 1A7O-L nrPDB 38 0.005 1DVF-C nrPDB 38 0.006 1VCA-A nrPDB 37 0.008 1MLC-A nrPDB 37 0.008 1A0Q-L nrPDB 36 0.014 1SVZ-A nrPDB 36 0.015 1KCU-L nrPDB 36 0.016 5VI4-C nrPDB 36 0.018 1F6L-L nrPDB 36 0.018 1D5B-A nrPDB 36 0.018 3F7V-B nrPDB 36 0.019 4D3C-L nrPDB 36 0.020 1E4W-L nrPDB 36 0.021 5XCV-B nrPDB 36 0.022 3MJ9-A nrPDB 35 0.026 1QFW-M nrPDB 35 0.028 3S35-X nrPDB 35 0.029 2AEP-L nrPDB 35 0.030 4Q6I-C nrPDB 35 0.031 3O2D-A nrPDB 35 0.031 1WIO-A nrPDB 35 0.031 2XOT-A nrPDB 35 0.040 4CKD-L nrPDB 35 0.041 6FAB-L nrPDB 35 0.042 1KCR-L nrPDB 35 0.042 3KG5-A nrPDB 35 0.043 3UEZ-A nrPDB 35 0.043 1CFS-A nrPDB 35 0.049 1KCS-L nrPDB 35 0.049 5XCS-B nrPDB 35 0.055 1FBI-L nrPDB 34 0.061 1C12-A nrPDB 34 0.066 2IG2-H nrPDB 34 0.067 5A2I-H nrPDB 34 0.069 1A14-L nrPDB 34 0.071 1IGY-A nrPDB 34 0.073 3UPA-A nrPDB 34 0.073 5EU6-D nrPDB 34 0.074 1FNS-L nrPDB 34 0.077 2ZNW-A nrPDB 34 0.079 4FRW-A nrPDB 34 0.082 1Z7Z-I nrPDB 33 0.10 3O4O-B nrPDB 33 0.11 5BRZ-D nrPDB 33 0.11 3WO4-B nrPDB 33 0.12 1CIC-A nrPDB 33 0.12 4PD4-K nrPDB 33 0.12 3NVQ-A nrPDB 33 0.12 1HEZ-A nrPDB 33 0.12 4XMP-L nrPDB 33 0.13 2RCJ-C nrPDB 33 0.13 2X1X-R nrPDB 33 0.14 4XNY-L nrPDB 33 0.16 2ADF-H nrPDB 33 0.16 5CEF-A nrPDB 33 0.17 3MOQ-A nrPDB 33 0.20 1AHW-A nrPDB 33 0.21 2PTT-A nrPDB 33 0.21 1EMT-L nrPDB 32 0.23 1JFQ-H nrPDB 32 0.24 4XNZ-L nrPDB 32 0.25 1DR9-A nrPDB 32 0.25 1PEW-A nrPDB 32 0.26 4WW2-A nrPDB 32 0.27 5B22-A nrPDB 32 0.29 4L1H-A nrPDB 31 0.38 3U0W-L nrPDB 31 0.39 1QGC-4 nrPDB 31 0.40 1ZVO-C nrPDB 31 0.47 3QS9-E nrPDB 31 0.51 5XCQ-A nrPDB 31 0.55 5XP1-A nrPDB 31 0.59 1KNO-A nrPDB 31 0.67 5K8D-B nrPDB 31 0.71 7FAB-L nrPDB 31 0.74 2BNR-D nrPDB 31 0.76 5F1N-B nrPDB 30 0.86 4JJH-A nrPDB 30 0.91 4GJT-B nrPDB 30 0.91 1HZH-H nrPDB 30 0.97 2Q20-A nrPDB 30 1.1 4BFI-B nrPDB 30 1.1 1B0W-A nrPDB 30 1.1 1QFW-L nrPDB 30 1.1 4WWK-A nrPDB 30 1.2 1SEQ-L nrPDB 30 1.2 1N26-A nrPDB 30 1.3 2QHR-L nrPDB 30 1.3 4E0R-B nrPDB 30 1.4 3O81-A nrPDB 30 1.4 5V4N-C nrPDB 30 1.5 4AH2-B nrPDB 30 1.5 1KG0-B nrPDB 30 1.5 5GJY-B nrPDB 30 1.6 4QNP-F nrPDB 29 1.8 2FD6-L nrPDB 29 1.8 5C09-D nrPDB 29 2.0 5IUE-B nrPDB 29 2.1 5NQK-B nrPDB 29 2.1 5DMK-B nrPDB 29 2.6 3O11-L nrPDB 29 2.9 4ONO-A nrPDB 29 3.0 1LIL-A nrPDB 28 3.7 5OWG-A nrPDB 28 3.8 1IAI-M nrPDB 27 7.2 >6FEY-A nrPDB Length = 242 Score = 358 bits (919), Expect = 1e-99, Method: Composition-based stats. Identities = 242/242 (100%), Positives = 242/242 (100%) Query: 26 RAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGS 85 RAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGS Sbjct: 1 RAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGS 60 Query: 86 QVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGS 145 QVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGS Sbjct: 61 QVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGS 120 Query: 146 KTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI 205 KTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI Sbjct: 121 KTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI 180 Query: 206 TWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNE 265 TWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNE Sbjct: 181 TWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNE 240 Query: 266 ED 267 ED Sbjct: 241 ED 242 >5O5G-A nrPDB Length = 385 Score = 170 bits (431), Expect = 4e-43, Method: Composition-based stats. Identities = 42/204 (20%), Positives = 72/204 (35%), Gaps = 37/204 (18%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVV--GHLPRSELDDLDSNQVAEEAPSAIVRVR 122 P+ L + E CE G VP+++W G LP+S + D + Sbjct: 206 PSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDH-------------- 251 Query: 123 SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKT 182 + I + +YTCV A +V +S T + P + + Sbjct: 252 TLKIRKVTAGDMGSYTCV---------AENMVGKAEAS-----ATLTVQEPPHFVVKPRD 297 Query: 183 HLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------GHRHRVLANGDLLISEIK 235 + +G + C P+ I W ++ ++ R V GDL I+ ++ Sbjct: 298 QVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQ 357 Query: 236 WEDMGNYKCIARNVVGKDTADTFV 259 D+G Y C NV G ++ Sbjct: 358 RSDVGYYICQTLNVAGSIITKAYL 381 Score = 109 bits (271), Expect = 1e-24, Method: Composition-based stats. Identities = 41/196 (20%), Positives = 71/196 (36%), Gaps = 27/196 (13%) Query: 65 PTKLQQADGATIEIVCEM-MGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRS 123 P+ + A G + C+ G P+I W P LDD D +R Sbjct: 114 PSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSP---LDDKDER--------ITIRGGK 162 Query: 124 SHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTH 183 I S+A Y CVG + +V R + ++P + Sbjct: 163 LMITYTRKSDAGKYVCVG---------TNMVG----ERESEVAELTVLERPSFVKRPSNL 209 Query: 184 LDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYK 243 + + + C P + W ++ + + R+ + + L I ++ DMG+Y Sbjct: 210 AVTVDDSAEFKCEARGDPVPTVRWRKDDGE--LPKSRYEIRDDHTLKIRKVTAGDMGSYT 267 Query: 244 CIARNVVGKDTADTFV 259 C+A N+VGK A + Sbjct: 268 CVAENMVGKAEASATL 283 Score = 96.5 bits (238), Expect = 1e-20, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 64/200 (32%), Gaps = 15/200 (7%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P+ L + G + C+ G P+I+W G R E D D PS + Sbjct: 12 PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGG-ERVETDKDDPRSHRMLLPSGSLFFLRI 70 Query: 125 HIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHL 184 + Y CV R + R + Sbjct: 71 VHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILR------------DDFRQNPSDVM 118 Query: 185 DLMGSNIQLPCRV-HARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYK 243 +G + C+ P I+W + + + R + G L+I+ + D G Y Sbjct: 119 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER-ITIRGGKLMITYTRKSDAGKYV 177 Query: 244 CIARNVVGKDTADTFVYPVL 263 C+ N+VG+ ++ VL Sbjct: 178 CVGTNMVGERESEVAELTVL 197 Score = 64.6 bits (155), Expect = 4e-11, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 32/92 (34%), Gaps = 9/92 (9%) Query: 173 KPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIV----QGHRHRVLANGD 228 PRI+ + G L C+ RP I W + +L +G Sbjct: 5 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 64 Query: 229 LLISEI-----KWEDMGNYKCIARNVVGKDTA 255 L I D G Y C+ARN +G+ + Sbjct: 65 LFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 96 >5Z5K-A nrPDB Length = 380 Score = 170 bits (429), Expect = 7e-43, Method: Composition-based stats. Identities = 41/199 (20%), Positives = 75/199 (37%), Gaps = 31/199 (15%) Query: 73 GATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLS 132 G T+ + CE++G +P+I W + + D N + ++ ++ + I Sbjct: 116 GDTVLLKCEVIGDPMPTIHW--------QKNQQDLNPIPGDSRVVVLPSGALQISRLQPG 167 Query: 133 EARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEK-----TYPGAQKPRIIYTEKTH-LDL 186 ++ Y C R P S+R E + PG + ++ + + Sbjct: 168 DSGVYRCSARN-------------PASTRTGNEAEVRILSDPGLHRQLYFLQRPSNVIAI 214 Query: 187 MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIA 246 G + L C V P TWL E ++ ++ +L +LLIS + +D G Y C+ Sbjct: 215 EGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGTYTCVV 274 Query: 247 ----RNVVGKDTADTFVYP 261 N+ V P Sbjct: 275 TYKNENISASAELTVLVPP 293 Score = 106 bits (263), Expect = 1e-23, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 72/197 (36%), Gaps = 29/197 (14%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P+ + +G + C + G PS W+ G E+ L S + + ++ + Sbjct: 208 PSNVIAIEGKDAVLECCVSGYPPPSFTWLRGE----EVIQLRSKKYS------LLGGSNL 257 Query: 125 HIIDHVLSEARTYTCVG--RTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKT 182 I + ++ TYTCV + + + A V P P + Sbjct: 258 LISNVTDDDSGTYTCVVTYKNENISASAELTVLVP----------------PWFLNHPSN 301 Query: 183 HLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNY 242 +I+ C V +P + W+ N + ++ +++ +L I + D G Y Sbjct: 302 LYAYESMDIEFECAVSGKPVPTVNWMKNGDV-VIPSDYFQIVGGSNLRILGVVKSDEGFY 360 Query: 243 KCIARNVVGKDTADTFV 259 +C+A N G + + Sbjct: 361 QCVAENEAGNAQSSAQL 377 Score = 90.7 bits (223), Expect = 6e-19, Method: Composition-based stats. Identities = 42/197 (21%), Positives = 70/197 (35%), Gaps = 19/197 (9%) Query: 63 TPPTKLQQADGATIEIVCEMMGSQ-VPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRV 121 + P+ G + + C + VP I+W L + D Q+ + + + Sbjct: 6 SEPSDAVTMRGGNVLLNCSAESDRGVPVIKWKKDGLILALGMDDRKQQLPNGS----LLI 61 Query: 122 RSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEK 181 ++ H + Y C G S ++ A R + + Sbjct: 62 QNILHSRHHKPDEGLYQCEASLGD------------SGSIISRTAKVMVAGPLRFLSQTE 109 Query: 182 THLDLMGSNIQLPCRVHARPRAEITWLNN-ENKEIVQG-HRHRVLANGDLLISEIKWEDM 239 + MG + L C V P I W N ++ + G R VL +G L IS ++ D Sbjct: 110 SITAFMGDTVLLKCEVIGDPMPTIHWQKNQQDLNPIPGDSRVVVLPSGALQISRLQPGDS 169 Query: 240 GNYKCIARNVVGKDTAD 256 G Y+C ARN T + Sbjct: 170 GVYRCSARNPASTRTGN 186 Score = 51.1 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 34/93 (36%), Gaps = 11/93 (11%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P+ L + IE C + G VP++ W+ + + V IV + Sbjct: 299 PSNLYAYESMDIEFECAVSGKPVPTVNWMK-----------NGDVVIPSDYFQIVGGSNL 347 Query: 125 HIIDHVLSEARTYTCVGRTGSKTIYASTVVHPP 157 I+ V S+ Y CV + +S + P Sbjct: 348 RILGVVKSDEGFYQCVAENEAGNAQSSAQLIVP 380 >6IAA-A nrPDB Length = 859 Score = 161 bits (407), Expect = 2e-40, Method: Composition-based stats. Identities = 41/206 (19%), Positives = 69/206 (33%), Gaps = 41/206 (19%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVV--GHLPRSELDDLDSNQVAEEAPSAIVRVR 122 P + +E C++ G P+++W LPR D D +R++ Sbjct: 221 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDD---------YTLRIK 271 Query: 123 SSHIIDHVLSEARTYTCVG--RTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTE 180 + + TY C+ R G A+ V P P+ + Sbjct: 272 KTMST-----DEGTYMCIAENRVGKMEASATLTVRAP----------------PQFVVRP 310 Query: 181 KTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIV-------QGHRHRVLANGDLLISE 233 + + G + PC P+ + W ++ ++ R V GDL I+ Sbjct: 311 RDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITN 370 Query: 234 IKWEDMGNYKCIARNVVGKDTADTFV 259 I+ D G Y C A V G A + Sbjct: 371 IQRSDAGYYICQALTVAGSILAKAQL 396 Score = 101 bits (251), Expect = 3e-22, Method: Composition-based stats. Identities = 47/217 (21%), Positives = 80/217 (36%), Gaps = 28/217 (12%) Query: 45 EEKPRNRAFEADWLKFT-KTPPTKLQQADGATIEIVCEM-MGSQVPSIQWVVGHLPRSEL 102 E RN + E L+ + PT + A G + C+ G P+I W + + Sbjct: 108 EAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKK---DKVRI 164 Query: 103 DDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRL 162 DD + +R I + S+A YTCVG + +V R Sbjct: 165 DDKEER--------ISIRGGKLMISNTRKSDAGMYTCVG---------TNMVG----ERD 203 Query: 163 TPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHR 222 + ++P + + L ++ C+V P+ + W ++ + R+ Sbjct: 204 SDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDAD--LPRGRYD 261 Query: 223 VLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFV 259 + + L I + D G Y CIA N VGK A + Sbjct: 262 IKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATL 298 Score = 100 bits (248), Expect = 7e-22, Method: Composition-based stats. Identities = 37/195 (18%), Positives = 65/195 (33%), Gaps = 11/195 (5%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P A G T+ CE G+ P++ W S+ + + ++ Sbjct: 310 PRDQIVAQGRTVTFPCETKGNPQPAVFWQK---EGSQNLLFPNQPQQPNSRCSVSPTGDL 366 Query: 125 HIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHL 184 I + S+A Y C T + +I A ++L P I+ Sbjct: 367 TITNIQRSDAGYYICQALTVAGSILAK--------AQLEVTDVLTDRPPPIILQGPANQT 418 Query: 185 DLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKC 244 + L C+ P I+WL + R + G L I ++ D G Y C Sbjct: 419 LAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTC 478 Query: 245 IARNVVGKDTADTFV 259 +A + G+ + + Sbjct: 479 VATSSSGETSWSAVL 493 Score = 99.6 bits (246), Expect = 1e-21, Method: Composition-based stats. Identities = 39/214 (18%), Positives = 71/214 (33%), Gaps = 15/214 (7%) Query: 44 EEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELD 103 ++++P +R + D+ P+ + + G + C+ G P+I+W R E D Sbjct: 6 DDKRPHSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEW-YKDGERVETD 64 Query: 104 DLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLT 163 D PS + + +Y CV R + Sbjct: 65 KDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVS------------R 112 Query: 164 PEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRV-HARPRAEITWLNNENKEIVQGHRHR 222 + + G L C+ P I W ++ + + R Sbjct: 113 NASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER-I 171 Query: 223 VLANGDLLISEIKWEDMGNYKCIARNVVGKDTAD 256 + G L+IS + D G Y C+ N+VG+ +D Sbjct: 172 SIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSD 205 >3S97-C nrPDB Length = 201 Score = 155 bits (392), Expect = 2e-38, Method: Composition-based stats. Identities = 50/211 (23%), Positives = 78/211 (36%), Gaps = 37/211 (17%) Query: 64 PPTK---LQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIV- 119 PP + ++ +G + ++C H P DDL + E P I Sbjct: 11 PPEERPEVRVKEGKGMVLLC----DP-------PYHFP----DDLSYRWLLNEFPVFITM 55 Query: 120 --------RVRSSHIIDHVLSEARTYTCVGRTGS--KTIYASTVVHPPRSSRLTPEKTYP 169 + +I + S+ Y+C + S K++++ + P R T K YP Sbjct: 56 DKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTT--KPYP 113 Query: 170 GAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDL 229 I+ K LMG N+ L C P +I W E + + L Sbjct: 114 A----DIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAVL 167 Query: 230 LISEIKWEDMGNYKCIARNVVGKDTADTFVY 260 I I+ ED G Y+C A N+ GKD +Y Sbjct: 168 KIFNIQLEDEGIYECEAENIRGKDKHQARIY 198 >2WIM-A nrPDB Length = 291 Score = 153 bits (386), Expect = 7e-38, Method: Composition-based stats. Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 35/202 (17%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P + +Q + A E+VC + S P++ W+ + E+ + N+ A ++ + Sbjct: 107 PQEFKQGEDA--EVVCRVSSSPAPAVSWLYHN---EEVTTISDNRFA------MLANNNL 155 Query: 125 HIIDHVLSEARTYTCVGRTGSK--TIYASTVV---HPPRSSRLTPEKTYPGAQKPRIIYT 179 I++ S+ Y C GR ++ + +V PP S P+K++ + Sbjct: 156 QILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAIS--MPQKSFNATAE------ 207 Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVL--ANGDLLISEIKWE 237 G + CR P I+W N ++++ + +L +N +L + I Sbjct: 208 -------RGEEMTFSCRASGSPEPAISWFRNG--KLIEENEKYILKGSNTELTVRNIINS 258 Query: 238 DMGNYKCIARNVVGKDTADTFV 259 D G Y C A N G+D F+ Sbjct: 259 DGGPYVCRATNKAGEDEKQAFL 280 Score = 62.2 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 41/186 (22%), Positives = 69/186 (37%), Gaps = 22/186 (11%) Query: 66 TKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSH 125 +K++ + G + C +G SI W + P+ E + + +V + R Sbjct: 12 SKVELSVGESKFFTCTAIGEPE-SIDW---YNPQGEK-IISTQRVVVQKEGVRSR---LT 63 Query: 126 IIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLD 185 I + + +A Y C +TVV E P K Sbjct: 64 IYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFK------------ 111 Query: 186 LMGSNIQLPCRVHARPRAEITW-LNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKC 244 G + ++ CRV + P ++W +NE + +R +LAN +L I I D G Y+C Sbjct: 112 -QGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRC 170 Query: 245 IARNVV 250 R Sbjct: 171 EGRVEA 176 Score = 48.4 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 4/78 (5%) Query: 188 GSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGD---LLISEIKWEDMGNYKC 244 G + C P I W N + ++I+ R V G L I ED G Y+C Sbjct: 19 GESKFFTCTAIGEPE-SIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYRC 77 Query: 245 IARNVVGKDTADTFVYPV 262 A + G+ T V + Sbjct: 78 QATDAKGQTQEATVVLEI 95 >3JXA-A nrPDB Length = 383 Score = 141 bits (354), Expect = 3e-34, Method: Composition-based stats. Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 13/170 (7%) Query: 98 PRSELDDLDSNQVAEEAPSA-------IVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYA 150 P +L + E PS + +I S+ YTCV + T+ Sbjct: 125 PPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVV---TNTVTN 181 Query: 151 STVVHPPRSSRLTPEKTYPGAQKPRI-IYTEKTHLDLMGSNIQLPCRVHARPRAEITWLN 209 V+ PP L + G +P+I + +T G+ ++L C P I W Sbjct: 182 HKVLGPPTPLILRNDGVM-GEYEPKIEVQFPETVPAEKGTTVKLECFALGNPVPTILWRR 240 Query: 210 NENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFV 259 + K I + R +NG L I + ED G+Y+C+A N GK+ A + Sbjct: 241 ADGKPIARKARRHK-SNGILEIPNFQQEDAGSYECVAENSRGKNVAKGQL 289 Score = 91.5 bits (225), Expect = 3e-19, Method: Composition-based stats. Identities = 36/187 (19%), Positives = 63/187 (33%), Gaps = 27/187 (14%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P + G T+++ C +G+ VP+I W D +A +A Sbjct: 211 PETVPAEKGTTVKLECFALGNPVPTILWRRA----------DGKPIARKARRHK-SNGIL 259 Query: 125 HIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHL 184 I + +A +Y CV A +P + Sbjct: 260 EIPNFQQEDAGSYECVAENSRGKNVAK--------------GQLTFYAQPNWVQIINDIH 305 Query: 185 DLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKC 244 M ++ C+ + RP+ WL N + + + + G L I+ + D G Y+C Sbjct: 306 VAMEESVFWECKANGRPKPTYRWLKNGDPLLTRDR--IQIEQGTLNITIVNLSDAGMYQC 363 Query: 245 IARNVVG 251 +A N G Sbjct: 364 VAENKHG 370 Score = 68.0 bits (164), Expect = 4e-12, Method: Composition-based stats. Identities = 36/187 (19%), Positives = 66/187 (35%), Gaps = 34/187 (18%) Query: 71 ADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDD-LDSNQVAEEAPSAIVRVRSSHIIDH 129 ++ +++ CE+ G+ P I+W L +++D +D + I + Sbjct: 20 SEEKKVKLSCEVKGNPKPHIRWK---LNGTDVDIGMDFRYSVVDGSLLINNPNKTQ---- 72 Query: 130 VLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDL-MG 188 +A TY C+ TI + E A ++ + + G Sbjct: 73 ---DAGTYQCIATNSFGTIVSR-------------EAKLQFAYLENFKTRTRSTVSVRRG 116 Query: 189 SNIQLPCRVHARPRA-----EITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYK 243 + L C P W+ NE R G+L I++++ D+GNY Sbjct: 117 QGMVLLC----GPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYT 172 Query: 244 CIARNVV 250 C+ N V Sbjct: 173 CVVTNTV 179 Score = 58.0 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 4/82 (4%) Query: 172 QKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLI 231 Q+P + LD ++L C V P+ I W N + + +G LLI Sbjct: 9 QEPSHVMFP---LDSEEKKVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVVDGSLLI 65 Query: 232 SEI-KWEDMGNYKCIARNVVGK 252 + K +D G Y+CIA N G Sbjct: 66 NNPNKTQDAGTYQCIATNSFGT 87 Score = 43.0 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 38/117 (32%), Gaps = 17/117 (14%) Query: 40 SIEAEEEKPRNRAFEADWLKFTKTPP-----TKLQQADGATIEIVCEMMGSQVPSIQWVV 94 S E E R + L F P + A ++ C+ G P+ +W+ Sbjct: 271 SYECVAENSRGKNVAKGQLTFYAQPNWVQIINDIHVAMEESVFWECKANGRPKPTYRWLK 330 Query: 95 GHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYAS 151 P D + Q + +I LS+A Y CV I++S Sbjct: 331 NGDPLLTRDRIQIEQ------------GTLNITIVNLSDAGMYQCVAENKHGVIFSS 375 >6DLF-A nrPDB Length = 306 Score = 126 bits (317), Expect = 6e-30, Method: Composition-based stats. Identities = 41/199 (20%), Positives = 70/199 (35%), Gaps = 34/199 (17%) Query: 66 TKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSH 125 + + +G I + C G P++ W ++ +A + Sbjct: 121 SDISINEGNNISLTCIATGRPEPTVTWRH---------------ISPKAVGFVSEDEYLE 165 Query: 126 IIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLD 185 I ++ Y C AS V P R+ YP P I + T + Sbjct: 166 IQGITREQSGDYEC---------SASNDVAAPVVRRVKVTVNYP----PYISEAKGTGVP 212 Query: 186 LMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLAN----GDLLISEIKWEDMGN 241 + G L C A P AE W ++ K +++G + + N L+ + D GN Sbjct: 213 V-GQKGTLQCEASAVPSAEFQWYKDD-KRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGN 270 Query: 242 YKCIARNVVGKDTADTFVY 260 Y C+A N +G A ++ Sbjct: 271 YTCVASNKLGHTNASIMLF 289 Score = 69.9 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 37/186 (19%), Positives = 68/186 (36%), Gaps = 28/186 (15%) Query: 67 KLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSH- 125 + G + + C + ++V + W L RS + +++ + ++ + Sbjct: 22 NVTVRQGESATLRC-TIDNRVTRVAW----LNRSTILYAGNDKWCLDPRVVLLSNTQTQY 76 Query: 126 ---IIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKT 182 I + + + YTC +T + P++SR+ P+I+ Sbjct: 77 SIEIQNVDVYDEGPYTCSVQTDNH----------PKTSRVH----LIVQVSPKIVEISSD 122 Query: 183 HLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNY 242 G+NI L C RP +TW + I V + L I I E G+Y Sbjct: 123 ISINEGNNISLTCIATGRPEPTVTWRH-----ISPKAVGFVSEDEYLEIQGITREQSGDY 177 Query: 243 KCIARN 248 +C A N Sbjct: 178 ECSASN 183 Score = 31.4 bits (69), Expect = 0.44, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 23/90 (25%), Gaps = 15/90 (16%) Query: 72 DGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVR----SSHII 127 G + CE QW D ++ E V R Sbjct: 213 VGQKGTLQCEASAVPSAEFQWYK-----------DDKRLIEGKKGVKVENRPFLSKLIFF 261 Query: 128 DHVLSEARTYTCVGRTGSKTIYASTVVHPP 157 + + YTCV AS ++ P Sbjct: 262 NVSEHDYGNYTCVASNKLGHTNASIMLFGP 291 >1QZ1-A nrPDB Length = 291 Score = 101 bits (250), Expect = 4e-22, Method: Composition-based stats. Identities = 34/207 (16%), Positives = 69/207 (33%), Gaps = 26/207 (12%) Query: 58 LKFTKTP-PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPS 116 L F P P + ++ + A I VC+++ S P+I W + + ++ Sbjct: 101 LMFKNAPTPQEFKEGEDAVI--VCDVVSSLPPTIIWKH----KGR-----DVILKKDVRF 149 Query: 117 AIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRI 176 ++ I ++ TY C GR ++ + ++ + I Sbjct: 150 IVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDI------QVIVNVPPTVQARQSI 203 Query: 177 IYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQG----HRHRVLANGDLLIS 232 + +G ++ L C P ++W + + + +L I Sbjct: 204 VNAT----ANLGQSVTLVCDADGFPEPTMSWTKDGEPIENEEEDDEKHIFSDDSSELTIR 259 Query: 233 EIKWEDMGNYKCIARNVVGKDTADTFV 259 + D Y CIA N G+ A + Sbjct: 260 NVDKNDEAEYVCIAENKAGEQDASIHL 286 Score = 67.3 bits (162), Expect = 8e-12, Method: Composition-based stats. Identities = 36/185 (19%), Positives = 64/185 (34%), Gaps = 20/185 (10%) Query: 65 PTKLQQADGATIEIVCEMMGSQV-PSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRS 123 P++ + + G + +C++ G I W + + + + V + S+ + Sbjct: 9 PSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLT--- 65 Query: 124 SHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTH 183 I + + +A Y CV T +TV + P K Sbjct: 66 --IYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFK---------- 113 Query: 184 LDLMGSNIQLPCRVHARPRAEITWL-NNENKEIVQGHRHRVLANGDLLISEIKWEDMGNY 242 G + + C V + I W + + + R VL+N L I IK D G Y Sbjct: 114 ---EGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTY 170 Query: 243 KCIAR 247 +C R Sbjct: 171 RCEGR 175 Score = 39.1 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 15/98 (15%), Positives = 35/98 (35%), Gaps = 9/98 (9%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARP-RAEITWLNNENKEIVQGHRHRVL-----ANGD 228 ++ +G + C+V +I+W + +++ + + + Sbjct: 4 QVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSST 63 Query: 229 LLISEIKWEDMGNYKCIARNVVG---KDTADTFVYPVL 263 L I +D G YKC+ G + T + ++ L Sbjct: 64 LTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKL 101 >1TLK-A nrPDB Length = 154 Score = 93.1 bits (229), Expect = 1e-19, Method: Composition-based stats. Identities = 30/99 (30%), Positives = 45/99 (45%), Gaps = 11/99 (11%) Query: 170 GAQKPRII-YTEKTHLDL---MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVL- 224 +KP + Y KT LD+ GS + C+V P E+ W ++N V+ RH + Sbjct: 34 AEEKPHVKPYFTKTILDMDVVEGSAARFDCKVEGYPDPEVMWFKDDNP--VKESRHFQID 91 Query: 225 ----ANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFV 259 N L ISE+ +D Y C A N +G+ T + Sbjct: 92 YDEEGNCSLTISEVCGDDDAKYTCKAVNSLGEATCTAEL 130 Score = 44.5 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 46/130 (35%), Gaps = 24/130 (18%) Query: 33 DSNDVDNSI----EAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVP 88 ++N V+N E EEKP + + FTKT + +G+ C++ G P Sbjct: 19 NANKVENEDAFLEEVAEEKPHVKPY------FTKTI-LDMDVVEGSAARFDCKVEGYPDP 71 Query: 89 SIQWVVGHLP--RSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVG--RTG 144 + W P S +D ++ S I + + YTC G Sbjct: 72 EVMWFKDDNPVKESRHFQIDYDEEGNC---------SLTISEVCGDDDAKYTCKAVNSLG 122 Query: 145 SKTIYASTVV 154 T A +V Sbjct: 123 EATCTAELLV 132 >6DLD-B nrPDB Length = 304 Score = 91.1 bits (224), Expect = 4e-19, Method: Composition-based stats. Identities = 36/210 (17%), Positives = 63/210 (30%), Gaps = 41/210 (19%) Query: 62 KTPP------TKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAP 115 + PP + +G + + C G PSI W P ++ Sbjct: 110 QVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWR-HISPSAK-------------- 154 Query: 116 SAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPR 175 + +D + G A V P ++ + Sbjct: 155 ----PFENGQYLDIY----GITR--DQAGEYECSAENDVSFPDVRKVKVVVNFAPT---- 200 Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLAN----GDLLI 231 I K+ G + + C P W E K++ G + ++ N L + Sbjct: 201 -IQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGE-KKLFNGQQGIIIQNFSTRSILTV 258 Query: 232 SEIKWEDMGNYKCIARNVVGKDTADTFVYP 261 + + E GNY C+A N +G A + P Sbjct: 259 TNVTQEHFGNYTCVAANKLGTTNASLPLNP 288 Score = 69.2 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 34/182 (18%), Positives = 54/182 (29%), Gaps = 21/182 (11%) Query: 67 KLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHI 126 + G T + C + W+ D S + R S I Sbjct: 21 NMMVRKGDTAVLRCYLE-DGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQI 79 Query: 127 IDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDL 186 + +++ YTC +T H PR T + P+I Sbjct: 80 QNVDVTDDGPYTCSVQTQ----------HTPR----TMQVHLTVQVPPKIYDISNDMTVN 125 Query: 187 MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIA 246 G+N+ L C +P I+W + + L I I + G Y+C A Sbjct: 126 EGTNVTLTCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSA 179 Query: 247 RN 248 N Sbjct: 180 EN 181 Score = 40.3 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 34/97 (35%), Gaps = 7/97 (7%) Query: 70 QADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDH 129 G + I CE G P+ +W G + + + + +I+ + + Sbjct: 209 VTPGRSGLIRCEGAGVPPPAFEWYKGE--KKLFNGQQGIIIQNFSTRSILT-----VTNV 261 Query: 130 VLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEK 166 YTCV T AS ++PP +++ Sbjct: 262 TQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITG 298 >3V2A-R nrPDB Length = 772 Score = 77.3 bits (188), Expect = 6e-15, Method: Composition-based stats. Identities = 37/204 (18%), Positives = 69/204 (33%), Gaps = 22/204 (10%) Query: 67 KLQQADGATIEIVCEMMGSQVPSIQWVV----------GHLPRSELDDLDSNQVAEE--A 114 +Q + ++ + C S ++ W G LP +LD+ Sbjct: 558 DMQPTEQESVSLWCTADRSTFENLTWYKLGPQPLPIHVGELPTPVCKNLDTLWKLNATMF 617 Query: 115 PSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKP 174 ++ + + + L + Y C+ + KT VV + T P Sbjct: 618 SNSTNDILIMELKNASLQDQGDYVCLAQ-DRKTKKRHCVVR---------QLTVLERVAP 667 Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEI 234 I + +G +I++ C P +I W + + N +L I + Sbjct: 668 TITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGNRNLTIRRV 727 Query: 235 KWEDMGNYKCIARNVVGKDTADTF 258 + ED G Y C A +V+G + F Sbjct: 728 RKEDEGLYTCQACSVLGCAKVEAF 751 Score = 69.6 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 42/197 (21%), Positives = 68/197 (34%), Gaps = 18/197 (9%) Query: 63 TPPTKLQQADGATIEIVCEMMGSQVPSI--QWVVGHLPRSELDDLDSNQVAEEAPSAIVR 120 +P ++ + G + + C I W + + L + + ++ S + + Sbjct: 229 SPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPS-SKHQHKKLVNRDLKTQSGSEMKK 287 Query: 121 VRSSHIID-HVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYT 179 S+ ID S+ YTC +G T ST V EK + Sbjct: 288 FLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVRV-------HEKPFVAFGSGMESLV 340 Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDM 239 E T G +++P + P EI W N H + A L I E+ D Sbjct: 341 EATV----GERVRIPAKYLGYPPPEIKWYKNGIPL---ESNHTIKAGHVLTIMEVSERDT 393 Query: 240 GNYKCIARNVVGKDTAD 256 GNY I N + K+ Sbjct: 394 GNYTVILTNPISKEKQS 410 Score = 45.7 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 41/240 (17%), Positives = 69/240 (28%), Gaps = 58/240 (24%) Query: 51 RAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQV 110 R E ++ F + ++ G + I + +G P I+W N + Sbjct: 323 RVHEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYK-------------NGI 369 Query: 111 AEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPG 170 E+ I I++ + YT + S VV + P+ Sbjct: 370 PLESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVS--LVVYVPPQIGEKS 427 Query: 171 AQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRA-EITW---------------------- 207 P Y G+ L C V+A P I W Sbjct: 428 LISPVDSYQY-------GTTQTLTCTVYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPY 480 Query: 208 ----------LNNENKEIVQGHRHRVLANGDLLISE--IKWED-MGNYKCIARNVVGKDT 254 NK V ++ ++ + +S I+ + YKC A N VG+ Sbjct: 481 PCEEWRSVEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKVGRGE 540 Score = 33.0 bits (73), Expect = 0.14, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 34/98 (34%), Gaps = 13/98 (13%) Query: 175 RIIYTEKTHLDLM-GSNIQLPC--RVHARPRAEITWL----NNENKEIVQGHRHRVLAN- 226 ++ + ++L G + L C R + W +++K++V + Sbjct: 225 DVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSE 284 Query: 227 -----GDLLISEIKWEDMGNYKCIARNVVGKDTADTFV 259 L I + D G Y C A + + TFV Sbjct: 285 MKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFV 322 >5OJ2-A nrPDB Length = 910 Score = 71.5 bits (173), Expect = 4e-13, Method: Composition-based stats. Identities = 35/185 (18%), Positives = 61/185 (32%), Gaps = 17/185 (9%) Query: 75 TIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIV-RVRSSHIIDHVLSE 133 T+ + C + + W G L N V P + + + + Sbjct: 134 TVFLRCTVNSNPPARFIWKRG---AETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQD 190 Query: 134 ARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQL 193 +YTC V P S ++ +T + G N+ + Sbjct: 191 YASYTCQVSV-------RNVCSIPDKSITFQLTNTTAPPALKLSVN-ETLVVNPGDNVTM 242 Query: 194 PCRVHA-RPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGK 252 C + P+ E+ W + + + + ++ G+L I I+ ED G Y C A N VG Sbjct: 243 QCSLTGGDPQPEVLW--SHSPGPLPPN--SLVQGGNLTIWRIRVEDSGYYNCTAINNVGN 298 Query: 253 DTADT 257 T Sbjct: 299 PAKKT 303 Score = 71.1 bits (172), Expect = 4e-13, Method: Composition-based stats. Identities = 38/184 (20%), Positives = 56/184 (30%), Gaps = 18/184 (9%) Query: 73 GATIEIVCEMMGSQVPSI--QWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHV 130 G +++ C + + W P D L + E P S IID Sbjct: 332 GQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTC---SLEIIDLR 388 Query: 131 LSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEK--THLDLMG 188 S+ TY CV T P P I + T G Sbjct: 389 FSDYGTYLCVA----------TFQGAPIPDLSVEVNISSETVPPTISVPKGQSTITVREG 438 Query: 189 SNIQLPCRVHARPRAEITWLNNENKEIVQ-GHRHRVLANGDLLISEIKWEDMGNYKCIAR 247 S +L C V +P+ I W + + + G +G L + + + G YKC Sbjct: 439 SRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGTYKCQTA 498 Query: 248 NVVG 251 G Sbjct: 499 RYNG 502 Score = 66.1 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 56/187 (29%), Gaps = 36/187 (19%) Query: 72 DGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVL 131 +G T+ + C + G P ++W S+ V + I Sbjct: 34 EGDTLVLQCLVTGHPRPQVRWTKTAGSASDK-----------FQETSVLNETLRIEKIQR 82 Query: 132 SEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMG--- 188 + Y C G V P + + Y +P + +T D+ G Sbjct: 83 LQGGRYYCKAENG---------VGVPAIKSIRVDVQY--LDEPVLTVH-QTISDVRGSFY 130 Query: 189 --SNIQLPCRVHARPRAEITWLNN--------ENKEIVQGHRHRVLANGDLLISEIKWED 238 + L C V++ P A W +N + + L + ++ +D Sbjct: 131 QEKTVFLRCTVNSNPPARFIWKRGAETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQD 190 Query: 239 MGNYKCI 245 +Y C Sbjct: 191 YASYTCQ 197 Score = 64.2 bits (154), Expect = 5e-11, Method: Composition-based stats. Identities = 41/212 (19%), Positives = 70/212 (33%), Gaps = 48/212 (22%) Query: 58 LKFTKTPPT-------KLQQADGATIEIVCEMMG-SQVPSIQWVVGHLPRSELDDLDSNQ 109 L T PP L G + + C + G P + W P Sbjct: 215 LTNTTAPPALKLSVNETLVVNPGDNVTMQCSLTGGDPQPEVLWSHSPGPL---------- 264 Query: 110 VAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRL----TPE 165 P+++V+ + I + ++ Y C A V P + Sbjct: 265 ----PPNSLVQGGNLTIWRIRVEDSGYYNC---------TAINNVGNPAKKTVNLLVRSM 311 Query: 166 KTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEIVQGHRHRV 223 K P +I +T +G +++L C V A P+ ++ +W N K R + Sbjct: 312 KNATFQITPDVIKESETI--QLGQDLKLSCHVDAVPQEKVVYSWYKNG-KPARFSDRLLI 368 Query: 224 LAN--------GDLLISEIKWEDMGNYKCIAR 247 N L I ++++ D G Y C+A Sbjct: 369 TRNDPELPPVTCSLEIIDLRFSDYGTYLCVAT 400 Score = 64.2 bits (154), Expect = 6e-11, Method: Composition-based stats. Identities = 34/196 (17%), Positives = 63/196 (32%), Gaps = 30/196 (15%) Query: 66 TKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSH 125 + + +G+ E+ CE+ G P I W S +D + + Sbjct: 431 STITVREGSRAELQCEVRGKPKPPIIW-------SRVD--KETPMPSGTMTVETYDGKLR 481 Query: 126 IIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLD 185 + + TY C +T + PR + + +P +P + Sbjct: 482 LESVSRDMSGTYKC--QTARYNGFN----IRPREALVQLNVQFPPVVEPAF----QDVRQ 531 Query: 186 LMGSNIQLPCRVH-ARP--RAEITWLNNEN---KEIVQGHRHRVLANGDLLISEIKWEDM 239 MG ++ L C + P A W N + + + +L + + E Sbjct: 532 GMGRSVTLRCTMLKGSPMKVATSVWRFNGTLLAQPPAEQQDY-----SELKVDSVSRETS 586 Query: 240 GNYKCIARNVVGKDTA 255 G+Y+C N VG Sbjct: 587 GSYECSISNDVGVSAC 602 Score = 51.8 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 36/98 (36%), Gaps = 3/98 (3%) Query: 154 VHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENK 213 V+ P +++ ++ I T G + L C V PR ++ W Sbjct: 3 VYAPAQAQIIHAGQACVVKEDNISERVYTI--REGDTLVLQCLVTGHPRPQVRWTKTAGS 60 Query: 214 EIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVG 251 + VL N L I +I+ G Y C A N VG Sbjct: 61 ASDKFQETSVL-NETLRIEKIQRLQGGRYYCKAENGVG 97 >3V6B-R nrPDB Length = 424 Score = 69.6 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 42/197 (21%), Positives = 68/197 (34%), Gaps = 18/197 (9%) Query: 63 TPPTKLQQADGATIEIVCEMMGSQVPSI--QWVVGHLPRSELDDLDSNQVAEEAPSAIVR 120 +P ++ + G + + C I W + + L + + ++ S + + Sbjct: 99 SPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPS-SKHQHKKLVNRDLKTQSGSEMKK 157 Query: 121 VRSSHIID-HVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYT 179 S+ ID S+ YTC +G T ST V EK + Sbjct: 158 FLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVRV-------HEKPFVAFGSGMESLV 210 Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDM 239 E T G +++P + P EI W N H + A L I E+ D Sbjct: 211 EATV----GERVRIPAKYLGYPPPEIKWYKNGIPL---ESNHTIKAGHVLTIMEVSERDT 263 Query: 240 GNYKCIARNVVGKDTAD 256 GNY I N + K+ Sbjct: 264 GNYTVILTNPISKEKQS 280 Score = 45.7 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 41/240 (17%), Positives = 69/240 (28%), Gaps = 58/240 (24%) Query: 51 RAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQV 110 R E ++ F + ++ G + I + +G P I+W N + Sbjct: 193 RVHEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYK-------------NGI 239 Query: 111 AEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPG 170 E+ I I++ + YT + S VV + P+ Sbjct: 240 PLESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVS--LVVYVPPQIGEKS 297 Query: 171 AQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRA-EITW---------------------- 207 P Y G+ L C V+A P I W Sbjct: 298 LISPVDSYQY-------GTTQTLTCTVYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPY 350 Query: 208 ----------LNNENKEIVQGHRHRVLANGDLLISE--IKWED-MGNYKCIARNVVGKDT 254 NK V ++ ++ + +S I+ + YKC A N VG+ Sbjct: 351 PCEEWRSVEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKVGRGE 410 Score = 33.0 bits (73), Expect = 0.14, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 34/98 (34%), Gaps = 13/98 (13%) Query: 175 RIIYTEKTHLDLM-GSNIQLPC--RVHARPRAEITWL----NNENKEIVQGHRHRVLAN- 226 ++ + ++L G + L C R + W +++K++V + Sbjct: 95 DVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSE 154 Query: 227 -----GDLLISEIKWEDMGNYKCIARNVVGKDTADTFV 259 L I + D G Y C A + + TFV Sbjct: 155 MKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFV 192 >1EPF-A nrPDB Length = 191 Score = 68.4 bits (165), Expect = 3e-12, Method: Composition-based stats. Identities = 36/185 (19%), Positives = 64/185 (34%), Gaps = 20/185 (10%) Query: 65 PTKLQQADGATIEIVCEMMGSQV-PSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRS 123 P++ + + G + +C++ G I W + + + + V + S+ + Sbjct: 9 PSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLT--- 65 Query: 124 SHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTH 183 I + + +A Y CV T +TV + P K Sbjct: 66 --IYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFK---------- 113 Query: 184 LDLMGSNIQLPCRVHARPRAEITWL-NNENKEIVQGHRHRVLANGDLLISEIKWEDMGNY 242 G + + C V + I W + + + R VL+N L I IK D G Y Sbjct: 114 ---EGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTY 170 Query: 243 KCIAR 247 +C R Sbjct: 171 RCEGR 175 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 36/90 (40%), Gaps = 12/90 (13%) Query: 58 LKFTKTP-PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPS 116 L F P P + ++ + A I VC+++ S P+I W + + ++ Sbjct: 101 LMFKNAPTPQEFKEGEDAVI--VCDVVSSLPPTIIWKH----KGR-----DVILKKDVRF 149 Query: 117 AIVRVRSSHIIDHVLSEARTYTCVGRTGSK 146 ++ I ++ TY C GR ++ Sbjct: 150 IVLSNNYLQIRGIKKTDEGTYRCEGRILAR 179 Score = 39.9 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 32/85 (37%), Gaps = 9/85 (10%) Query: 188 GSNIQLPCRVHARP-RAEITWLNNENKEIVQGHRHRVL-----ANGDLLISEIKWEDMGN 241 G + C+V +I+W + +++ + + + L I +D G Sbjct: 17 GESKFFLCQVAGDAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGI 76 Query: 242 YKCIARNVVG---KDTADTFVYPVL 263 YKC+ G + T + ++ L Sbjct: 77 YKCVVTAEDGTQSEATVNVKIFQKL 101 >6A77-A nrPDB Length = 91 Score = 68.4 bits (165), Expect = 3e-12, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 29/86 (33%) Query: 174 PRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISE 233 P I + L C P I W + Q R + L NG L I Sbjct: 3 PVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRY 62 Query: 234 IKWEDMGNYKCIARNVVGKDTADTFV 259 K D G Y CIA G+ T ++ Sbjct: 63 AKLGDTGRYTCIASTPSGEATWSAYI 88 Score = 48.8 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 26/85 (30%), Gaps = 10/85 (11%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P A T + C GS VP+I W + S D + + Sbjct: 9 PVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQD----------SRIKQLENGVL 58 Query: 125 HIIDHVLSEARTYTCVGRTGSKTIY 149 I L + YTC+ T S Sbjct: 59 QIRYAKLGDTGRYTCIASTPSGEAT 83 >2XY2-A nrPDB Length = 189 Score = 67.6 bits (163), Expect = 5e-12, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 41/92 (44%), Gaps = 13/92 (14%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P + +Q + A E+VC + S P++ W+ + E+ + N+ A ++ + Sbjct: 105 PQEFKQGEDA--EVVCRVSSSPAPAVSWLYHN---EEVTTISDNRFA------MLANNNL 153 Query: 125 HIIDHVLSEARTYTCVGRTGSK--TIYASTVV 154 I++ S+ Y C GR ++ + +V Sbjct: 154 QILNINKSDEGIYRCEGRVEARGEIDFRDIIV 185 Score = 62.6 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 41/186 (22%), Positives = 69/186 (37%), Gaps = 22/186 (11%) Query: 66 TKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSH 125 +K++ + G + C +G SI W + P+ E + + +V + R Sbjct: 10 SKVELSVGESKFFTCTAIGEPE-SIDW---YNPQGEK-IISTQRVVVQKEGVRSR---LT 61 Query: 126 IIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLD 185 I + + +A Y C +TVV E P K Sbjct: 62 IYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFK------------ 109 Query: 186 LMGSNIQLPCRVHARPRAEITW-LNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKC 244 G + ++ CRV + P ++W +NE + +R +LAN +L I I D G Y+C Sbjct: 110 -QGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRC 168 Query: 245 IARNVV 250 R Sbjct: 169 EGRVEA 174 Score = 48.8 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 4/78 (5%) Query: 188 GSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGD---LLISEIKWEDMGNYKC 244 G + C P I W N + ++I+ R V G L I ED G Y+C Sbjct: 17 GESKFFTCTAIGEPE-SIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYRC 75 Query: 245 IARNVVGKDTADTFVYPV 262 A + G+ T V + Sbjct: 76 QATDAKGQTQEATVVLEI 93 >2EO9-A nrPDB Length = 118 Score = 67.3 bits (162), Expect = 6e-12, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 29/87 (33%) Query: 173 KPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLIS 232 P I + L C P I W + Q R + L NG L I Sbjct: 8 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIR 67 Query: 233 EIKWEDMGNYKCIARNVVGKDTADTFV 259 K D G Y CIA G+ T ++ Sbjct: 68 YAKLGDTGRYTCIASTPSGEATWSAYI 94 Score = 47.6 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 32/105 (30%), Gaps = 19/105 (18%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P A T + C GS VP+I W + S D + + Sbjct: 15 PVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQD----------SRIKQLENGVL 64 Query: 125 HIIDHVLSEARTYTCVGRTGSKTIYAS---------TVVHPPRSS 160 I L + YTC+ T S S V PPR + Sbjct: 65 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPT 109 >3UTO-A nrPDB Length = 573 Score = 64.6 bits (155), Expect = 4e-11, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 4/119 (3%) Query: 144 GSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRA 203 G + Y+S H P+ + +PR I G + CRV A Sbjct: 453 GRISNYSSLRKHRPQEYSIRDAFWDRSEAQPRFIVKPYGTEVGEGQSANFYCRVIASSPP 512 Query: 204 EITWLNNENKEIVQGHRHRVLANGD---LLISEIKWEDMGNYKCIARNVVGKDTADTFV 259 +TW ++ +E+ Q ++ NG+ L I+ +K +D G Y A+N G F+ Sbjct: 513 VVTWHKDD-RELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEEIVFL 570 Score = 35.3 bits (79), Expect = 0.027, Method: Composition-based stats. Identities = 17/113 (15%), Positives = 34/113 (30%), Gaps = 14/113 (12%) Query: 37 VDNSIEAEEEKPRNRAF-EADWLKFTKTP-----PTKLQQADGATIEIVCEMMGSQVPSI 90 + N + +P+ + +A W + P P + +G + C ++ S P + Sbjct: 455 ISNYSSLRKHRPQEYSIRDAFWDRSEAQPRFIVKPYGTEVGEGQSANFYCRVIASSPPVV 514 Query: 91 QWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRT 143 W DD + Q + I + YT + Sbjct: 515 TWHK--------DDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKN 559 >1KOA-A nrPDB Length = 491 Score = 64.6 bits (155), Expect = 4e-11, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 4/119 (3%) Query: 144 GSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRA 203 G + Y+S H P+ + +PR I G + CRV A Sbjct: 347 GRISNYSSLRKHRPQEYSIRDAFWDRSEAQPRFIVKPYGTEVGEGQSANFYCRVIASSPP 406 Query: 204 EITWLNNENKEIVQGHRHRVLANGD---LLISEIKWEDMGNYKCIARNVVGKDTADTFV 259 +TW ++ +E+ Q ++ NG+ L I+ +K +D G Y A+N G F+ Sbjct: 407 VVTWHKDD-RELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEEIVFL 464 Score = 36.8 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 22/147 (14%), Positives = 42/147 (28%), Gaps = 17/147 (11%) Query: 37 VDNSIEAEEEKPRNRAF-EADWLKFTKTP-----PTKLQQADGATIEIVCEMMGSQVPSI 90 + N + +P+ + +A W + P P + +G + C ++ S P + Sbjct: 349 ISNYSSLRKHRPQEYSIRDAFWDRSEAQPRFIVKPYGTEVGEGQSANFYCRVIASSPPVV 408 Query: 91 QWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTG---SKT 147 W DD + Q + I + YT + + Sbjct: 409 TWHK--------DDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEE 460 Query: 148 IYASTVVHPPRSSRLTPEKTYPGAQKP 174 I V + P + A P Sbjct: 461 IVFLNVTRHSEPLKFEPLEPMKKAPSP 487 >1U2H-A nrPDB Length = 99 Score = 59.9 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 30/91 (32%), Gaps = 3/91 (3%) Query: 172 QKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG---D 228 P + G ++ + RV P+ ++WL N R A G Sbjct: 4 APPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCR 63 Query: 229 LLISEIKWEDMGNYKCIARNVVGKDTADTFV 259 L I + D G Y C A N G + + Sbjct: 64 LRILAAERGDAGFYTCKAVNEYGARQCEARL 94 Score = 42.6 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 38/103 (36%), Gaps = 15/103 (14%) Query: 61 TKTPPT------KLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEA 114 +K PPT +G + + + G P + W+ P D + AEEA Sbjct: 2 SKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRP----DQRRFAEEA 57 Query: 115 PSAIVRVRSSHIIDHVLSEARTYTCVGRT--GSKTIYASTVVH 155 + R+R I+ +A YTC G++ A V Sbjct: 58 EGGLCRLR---ILAAERGDAGFYTCKAVNEYGARQCEARLEVR 97 >1E07-A nrPDB Length = 642 Score = 59.2 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 35/195 (17%), Positives = 58/195 (29%), Gaps = 41/195 (21%) Query: 64 PPTKLQQA-------DGATIEIVCEMMGSQVPSIQWVVGH-LPRSELDDLDSNQVAEEAP 115 PP + D + + CE + WV LP S L ++ Sbjct: 288 PPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSND------- 340 Query: 116 SAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPR 175 R+ ++ ++ Y C + ++ P + P Sbjct: 341 -----NRTLTLLSVTRNDVGPYECGIQNELSVDHSD-----PVILNVLYGPDDPTISPSY 390 Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIK 235 Y G N+ L C + P A+ +WL + N +L IS I Sbjct: 391 TYYRP-------GVNLSLSCHAASNPPAQYSWLIDGN---------IQQHTQELFISNIT 434 Query: 236 WEDMGNYKCIARNVV 250 ++ G Y C A N Sbjct: 435 EKNSGLYTCQANNSA 449 Score = 51.1 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 37/218 (16%), Positives = 61/218 (27%), Gaps = 23/218 (10%) Query: 58 LKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDS---NQVAEEA 114 L TP A+G + ++ + + W G + Q A Sbjct: 2 LTIESTP---FNVAEGKEVLLLVHNLPQHLFGYSWYKGERVDGNRQIIGYVIGTQQATPG 58 Query: 115 PSA-----IVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYP 169 P+ I S I + + ++ YT + YP Sbjct: 59 PAYSGREIIYPNASLLIQNIIQNDTGFYTLHVIKSDLV----------NEEATGQFRVYP 108 Query: 170 GAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDL 229 KP I + + + C + A W N V N L Sbjct: 109 ELPKPSIS-SNNSKPVEDKDAVAFTCEPETQ-DATYLWWVNNQSLPVSPRLQLSNGNRTL 166 Query: 230 LISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNEED 267 + + D +YKC +N V +D+ + VL D Sbjct: 167 TLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPD 204 Score = 49.5 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 38/187 (20%), Positives = 59/187 (31%), Gaps = 34/187 (18%) Query: 72 DGATIEIVCEMMGSQVPSIQWVVGH-LPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHV 130 D + CE + WV G LP S L + R+ + + Sbjct: 481 DKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNG------------NRTLTLFNVT 528 Query: 131 LSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSN 190 ++AR Y C + V RS +T + Y G P I L G+N Sbjct: 529 RNDARAYVCGIQ---------NSVSANRSDPVTLDVLY-GPDTPIIS--PPDSSYLSGAN 576 Query: 191 IQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVV 250 + L C + P + +W N + L I++I + G Y C N+ Sbjct: 577 LNLSCHSASNPSPQYSWRINGIPQQ---------HTQVLFIAKITPNNNGTYACFVSNLA 627 Query: 251 GKDTADT 257 Sbjct: 628 TGRNNSI 634 Score = 48.8 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 30/203 (14%), Positives = 60/203 (29%), Gaps = 30/203 (14%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P G + + C + W V + + Sbjct: 210 PLNTSYRSGENLNLSCHAASNPPAQYSWFVN-------------------GTFQQSTQEL 250 Query: 125 HIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHL 184 I + ++ + +YTC + +TV T I + ++ Sbjct: 251 FIPNITVNNSGSYTCQAHNSDTGLNRTTV----------TTITVYAEPPKPFITSNNSNP 300 Query: 185 DLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKC 244 + L C + + W+NN++ + N L + + D+G Y+C Sbjct: 301 VEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSP-RLQLSNDNRTLTLLSVTRNDVGPYEC 359 Query: 245 IARNVVGKDTADTFVYPVLNEED 267 +N + D +D + VL D Sbjct: 360 GIQNELSVDHSDPVILNVLYGPD 382 Score = 47.6 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 26/144 (18%), Positives = 38/144 (26%), Gaps = 11/144 (7%) Query: 124 SHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTH 183 I + + YTC + +TV S+ L KP Sbjct: 428 LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKP--------- 478 Query: 184 LDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYK 243 + C A+ W N V N L + + D Y Sbjct: 479 -VEDKDAVAFTCEPEAQ-NTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYV 536 Query: 244 CIARNVVGKDTADTFVYPVLNEED 267 C +N V + +D VL D Sbjct: 537 CGIQNSVSANRSDPVTLDVLYGPD 560 Score = 33.7 bits (75), Expect = 0.074, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 29/110 (26%), Gaps = 26/110 (23%) Query: 37 VDNSIEAEEEKPRNRAFEADWLKFTKTP---PTKLQQADGATIEIVCEMMGSQVPSIQWV 93 + NS+ A P D L TP P GA + + C + P W Sbjct: 539 IQNSVSANRSDP----VTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWR 594 Query: 94 VGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRT 143 + +P+ L I + TY C Sbjct: 595 INGIPQQHTQVL-------------------FIAKITPNNNGTYACFVSN 625 >5T89-X nrPDB Length = 646 Score = 58.4 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 37/212 (17%), Positives = 61/212 (28%), Gaps = 50/212 (23%) Query: 81 EMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCV 140 ++ P + W+ LP +E + R S I D +A YT + Sbjct: 332 KVKAFPSPEVVWLKDGLPATEKSAR-----------YLTRGYSLIIKDVTEEDAGNYTIL 380 Query: 141 GRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHAR 200 ++ + + P + + L +GS L C + Sbjct: 381 LSIKQSNVFKNL-------TATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGI 433 Query: 201 PRAEITWL-----------------NNENKEIVQG------------HRHRVLANGDLLI 231 P+ I W NNE I+ R ++ + + Sbjct: 434 PQPTIKWFWHPCNHNHSEARCDFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKMA 493 Query: 232 SEIKWED---MGNYKCIARNVVGKDTADTFVY 260 S + D G Y CIA N VG + Y Sbjct: 494 STLVVADSRISGIYICIASNKVGTVGRNISFY 525 Score = 57.6 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 30/184 (16%), Positives = 62/184 (33%), Gaps = 17/184 (9%) Query: 63 TPPTKLQQADGATIEIVCEMMGSQVPS---IQWVVGHLPRSELDDLDSNQVAEEAPSAIV 119 + P ++ G T+ + C + + + + W ++ + A + Sbjct: 209 STPRPVKLLRGHTLVLNCTAT-TPLNTRVQMTWSYPDEKNKRASVR--RRIDQSNSHANI 265 Query: 120 RVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYT 179 I + YTC R+G +T VH + + + + + Sbjct: 266 FYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVH------IYDKAFITVKHRKQQVLE 319 Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDM 239 + +L +V A P E+ WL + + R+ + L+I ++ ED Sbjct: 320 T----VAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARY-LTRGYSLIIKDVTEEDA 374 Query: 240 GNYK 243 GNY Sbjct: 375 GNYT 378 Score = 56.9 bits (135), Expect = 9e-09, Method: Composition-based stats. Identities = 34/203 (16%), Positives = 63/203 (31%), Gaps = 34/203 (16%) Query: 73 GATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLS 132 G+ + C G P+I+W + + + S I+ S+ Sbjct: 421 GSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARCD-FCSNNEESFILDADSNMGNRIESI 479 Query: 133 EARTYTCVGR--------------TGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178 R G+ +G AS V + ++ P + Sbjct: 480 TQRMAIIEGKNKMASTLVVADSRISGIYICIASNKVG-----TVGRNISFYITDVPNGFH 534 Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAEITW------------LNNENKEIVQGHRHRVLAN 226 + G +++L C V+ ++TW + +++ H + N Sbjct: 535 VNLEKMPTEGEDLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSISKQKMAITKEHSITLN 594 Query: 227 GDLLISEIKWEDMGNYKCIARNV 249 L I + +D G Y C ARNV Sbjct: 595 --LTIMNVSLQDSGTYACRARNV 615 Score = 44.9 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 31/194 (15%), Positives = 60/194 (30%), Gaps = 31/194 (15%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 P + +G + I C + P+I + P + + + Sbjct: 117 PEIIHMTEGRELVIPCRVTS---PNITVTLKKFPL-------DTLIPDGKRIIWDSRKGF 166 Query: 125 HIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHL 184 I + E TC + + H ++ + + + T + Sbjct: 167 IISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQIS-----------TPRPVK 215 Query: 185 DLMGSNIQLPCRVHA--RPRAEITWLNNENKE--------IVQGHRHRVLANGDLLISEI 234 L G + L C R ++TW + K I Q + H + L I ++ Sbjct: 216 LLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKM 275 Query: 235 KWEDMGNYKCIARN 248 + +D G Y C R+ Sbjct: 276 QNKDKGLYTCRVRS 289 >3K0W-A nrPDB Length = 218 Score = 58.4 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 34/196 (17%), Positives = 58/196 (29%), Gaps = 31/196 (15%) Query: 59 KFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAI 118 K T P +K G +++ C G QW N+ ++ Sbjct: 20 KITVNPESK-AVLAGQFVKLCCRATGHPFVQYQWFK------------MNKEIPNGNTSE 66 Query: 119 VRVRSSHIIDHVLSEARTYTCVGRTGSKTIYAS----TVVHPPRSSRLTPEKTYPGAQKP 174 + + H+ +A Y C ++ V P S + + + K Sbjct: 67 LIFNAVHV-----KDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGV--SESKL 119 Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEI 234 +I + + GS + L C P W NE + + ++ DL Sbjct: 120 QICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDL----- 174 Query: 235 KWEDMGNYKCIARNVV 250 E G Y C N Sbjct: 175 --EHQGTYWCHVYNDR 188 >5OYJ-C nrPDB Length = 234 Score = 54.9 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 6/91 (6%) Query: 169 PGAQKPRIIY---TEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLA 225 P A+KP + + E +G +++P + P EI W N H + A Sbjct: 2 PLAEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPL---ESNHTIKA 58 Query: 226 NGDLLISEIKWEDMGNYKCIARNVVGKDTAD 256 L I E+ D GNY I N + K+ Sbjct: 59 GHVLTIMEVSERDTGNYTVILTNPISKEKQS 89 Score = 43.8 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 40/237 (16%), Positives = 68/237 (28%), Gaps = 58/237 (24%) Query: 54 EADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEE 113 E ++ F + ++ G + I + +G P I+W N + E Sbjct: 5 EKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYK-------------NGIPLE 51 Query: 114 APSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQK 173 + I I++ + YT + S VV + P+ Sbjct: 52 SNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVS--LVVYVPPQIGEKSLIS 109 Query: 174 PRIIYTEKTHLDLMGSNIQLPCRVHARPRA-EITW------------------------- 207 P Y G+ L C V+A P I W Sbjct: 110 PVDSYQY-------GTTQTLTCTVYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCE 162 Query: 208 -------LNNENKEIVQGHRHRVLANGDLLISE--IKWED-MGNYKCIARNVVGKDT 254 NK V ++ ++ + +S I+ + YKC A N VG+ Sbjct: 163 EWRSVEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKVGRGE 219 >4KC3-B nrPDB Length = 309 Score = 54.5 bits (129), Expect = 5e-08, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 60/198 (30%), Gaps = 22/198 (11%) Query: 72 DGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVL 131 + + + C G ++ W +S + A + + Sbjct: 10 ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAA--------V 61 Query: 132 SEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNI 191 +++ YTC+ R+ + V T K P + S I Sbjct: 62 ADSGIYTCIVRSPTFNRTGYANV--------TIYKKQSDCNVPDYLMYSTVSGSEKNSKI 113 Query: 192 QLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCI---ARN 248 P A + W N + +QG R+R L+I + ED G+Y C N Sbjct: 114 YCPTIDLYNWTAPLEWFKN--CQALQGSRYR-AHKSFLVIDNVMTEDAGDYTCKFIHNEN 170 Query: 249 VVGKDTADTFVYPVLNEE 266 T + V +E+ Sbjct: 171 GANYSVTATRSFTVKDEQ 188 Score = 31.8 bits (70), Expect = 0.30, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 24/83 (28%), Gaps = 2/83 (2%) Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ--GHRHRVLANGDLLISEIKW 236 K L + + C +P + W ++ + + + L Sbjct: 2 FSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAV 61 Query: 237 EDMGNYKCIARNVVGKDTADTFV 259 D G Y CI R+ T V Sbjct: 62 ADSGIYTCIVRSPTFNRTGYANV 84 >5VI4-B nrPDB Length = 309 Score = 49.9 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 32/194 (16%), Positives = 52/194 (26%), Gaps = 22/194 (11%) Query: 72 DGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVL 131 + + + C G ++W S + + R + Sbjct: 11 ENEALIVRCPQRGRSTYPVEWYYSDTNESIPTQKRNRIFVSRDRLKFLPAR--------V 62 Query: 132 SEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNI 191 ++ Y CV R+ + V T K P P + I Sbjct: 63 EDSGIYACVIRSPNLNKTGYLNV--------TIHKKPPSCNIPDYLMYSTVRGSDKNFKI 114 Query: 192 QLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCI---ARN 248 P A + W N + +Q R R L I + +D G+Y C A N Sbjct: 115 TCPTIDLYNWTAPVQWFKN--CKALQEPRFR-AHRSYLFIDNVTHDDEGDYTCQFTHAEN 171 Query: 249 VVGKDTADTFVYPV 262 T + V Sbjct: 172 GTNYIVTATRSFTV 185 >4PBW-B nrPDB Length = 283 Score = 49.9 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 31/90 (34%), Gaps = 4/90 (4%) Query: 174 PRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG---DLL 230 P I + G N + C+ P ++ W + I + N L Sbjct: 182 PEISVSHVNLTVREGENAVITCQGSGSPLPDVDWTVADLHSINTHQTNLQWTNVHAIQLT 241 Query: 231 ISEIKWEDMGN-YKCIARNVVGKDTADTFV 259 + + ED G CIA NVVG A + Sbjct: 242 LVNVTSEDNGFLLTCIAENVVGMSQASVLL 271 Score = 35.7 bits (80), Expect = 0.024, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 23/78 (29%), Gaps = 8/78 (10%) Query: 67 KLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHI 126 L +G I C+ GS +P + W V L + A + Sbjct: 190 NLTVREGENAVITCQGSGSPLPDVDWTVADLHSINTHQTNLQWTNVHAIQLTL------- 242 Query: 127 IDHVLSEAR-TYTCVGRT 143 ++ + TC+ Sbjct: 243 VNVTSEDNGFLLTCIAEN 260 >4PBV-A nrPDB Length = 268 Score = 49.9 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 31/90 (34%), Gaps = 4/90 (4%) Query: 174 PRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG---DLL 230 P I + G N + C+ P ++ W + I + N L Sbjct: 167 PEISVSHVNLTVREGENAVITCQGSGSPLPDVDWTVADLHSINTHQTNLQWTNVHAIQLT 226 Query: 231 ISEIKWEDMGN-YKCIARNVVGKDTADTFV 259 + + ED G CIA NVVG A + Sbjct: 227 LVNVTSEDNGFLLTCIAENVVGMSQASVLL 256 Score = 35.7 bits (80), Expect = 0.024, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 23/78 (29%), Gaps = 8/78 (10%) Query: 67 KLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHI 126 L +G I C+ GS +P + W V L + A + Sbjct: 175 NLTVREGENAVITCQGSGSPLPDVDWTVADLHSINTHQTNLQWTNVHAIQLTL------- 227 Query: 127 IDHVLSEAR-TYTCVGRT 143 ++ + TC+ Sbjct: 228 VNVTSEDNGFLLTCIAEN 245 >5FTT-A nrPDB Length = 285 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 45/202 (22%), Positives = 72/202 (35%), Gaps = 34/202 (16%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQ--------WVVGHLPRSELDDLDSNQVAEEAPS 116 P I + C+ P++Q WV + SE + LD + + Sbjct: 27 PEDAYIIKSNPIALRCKAR----PAMQIFFKCNGEWVHQNEHVSE-ESLDESSGLKVREV 81 Query: 117 AIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTY---PGAQK 173 I R H + Y C A + + +S + + Y Q Sbjct: 82 FINVTRQQVEDFHGPED---YWC-------QCVAWSHLGTSKSRKASVRIAYLRKNFEQD 131 Query: 174 PRIIYTEKTHLDLMGSNIQLPCRV-HARPRAEITWLNNENKEIVQGHRHRVL-ANGDLLI 231 P+ + + G I L CR P AE+ WL NE + + A+ +L+I Sbjct: 132 PQ-----GREVPIEGM-IVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLII 185 Query: 232 SEIKWEDMGNYKCIARNVVGKD 253 + + D GNY C+A N+V K Sbjct: 186 RQARLSDSGNYTCMAANIVAKR 207 >5IMK-A nrPDB Length = 220 Score = 48.8 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 43/145 (29%), Gaps = 9/145 (6%) Query: 122 RSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEK 181 S + + + YTC + V + + L +K KP + Sbjct: 84 VSLQLSTLEMDDRSHYTCEV---TWQTPDGNQVVRDKITELRVQKL--SVSKPTVTTGSG 138 Query: 182 THLDL-MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMG 240 + G I L C+ P W + V LL D G Sbjct: 139 YGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIK---VATLSTLLFKPAVIADSG 195 Query: 241 NYKCIARNVVGKDTADTFVYPVLNE 265 +Y C A+ VG + V V+ + Sbjct: 196 SYFCTAKGQVGSEQHSDIVKFVVKD 220 >2VAJ-A nrPDB Length = 93 Score = 48.8 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 4/78 (5%) Query: 188 GSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGD---LLISEIKWEDMGNYKC 244 G + C P I W N + ++I+ R V G L I ED G Y+C Sbjct: 15 GESKFFTCTAIGEPE-SIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYRC 73 Query: 245 IARNVVGKDTADTFVYPV 262 A + G+ T V + Sbjct: 74 QATDAKGQTQEATVVLEI 91 Score = 32.2 bits (71), Expect = 0.27, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 34/90 (37%), Gaps = 8/90 (8%) Query: 66 TKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSH 125 +K++ + G + C +G SI W + P+ E + + +V + R Sbjct: 8 SKVELSVGESKFFTCTAIGEPE-SIDW---YNPQGEK-IISTQRVVVQKEGVRSR---LT 59 Query: 126 IIDHVLSEARTYTCVGRTGSKTIYASTVVH 155 I + + +A Y C +TVV Sbjct: 60 IYNANIEDAGIYRCQATDAKGQTQEATVVL 89 >3BFO-A nrPDB Length = 91 Score = 46.5 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 25/78 (32%), Gaps = 7/78 (8%) Query: 173 KPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLIS 232 K +I + + GS + L C P W NE + + ++ DL Sbjct: 3 KLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDL--- 59 Query: 233 EIKWEDMGNYKCIARNVV 250 E G Y C N Sbjct: 60 ----EHQGTYWCHVYNDR 73 Score = 34.1 bits (76), Expect = 0.068, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 18/34 (52%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLP 98 PT + G+T+ + C +GS +P QW LP Sbjct: 10 PTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELP 43 >1OLZ-A nrPDB Length = 663 Score = 46.1 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 19/125 (15%), Positives = 41/125 (32%), Gaps = 5/125 (4%) Query: 139 CVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVH 198 C + T A P + + + + H G +L C Sbjct: 499 CAWSPPTATCVALHQTESPSRGLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQK 558 Query: 199 ARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTF 258 + A + W + ++ ++ +LLI + D G Y+C++ + + Sbjct: 559 SN-LARVFWKFQNGVLKAESPKYGLMGRKNLLIFNLSEGDSGVYQCLSE----ERVKNKT 613 Query: 259 VYPVL 263 V+ V+ Sbjct: 614 VFQVV 618 >4FOM-A nrPDB Length = 308 Score = 45.3 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 34/199 (17%), Positives = 56/199 (28%), Gaps = 25/199 (12%) Query: 65 PTKLQQADGATIEIVC-EMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRS 123 P L T+ +C G V I W G L E E + I + + Sbjct: 121 PDSLIDGGNETVAAICIAATGKPVAHIDW-EGDLGEMESTTTS---FPNETATIISQYK- 175 Query: 124 SHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTH 183 + + R TCV + HP + P + T Sbjct: 176 --LFPTRFARGRRITCVVK------------HPALEKDIRYSFILDIQYAPEVSVTGYDG 221 Query: 184 LDLMGSN-IQLPCRVHARPRA-EITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGN 241 +G + L C A P + W + + N + + + G Sbjct: 222 NWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWP---DGLLASDNTLHFVHPLTFNYSGV 278 Query: 242 YKCIARNVVGKDTADTFVY 260 Y C N +G+ + +Y Sbjct: 279 YICKVTNSLGQRSDQKVIY 297 Score = 31.0 bits (68), Expect = 0.56, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 36/114 (31%), Gaps = 26/114 (22%) Query: 177 IYTEKTHLDLMGSNIQLPCRVHARPR-AEITWLNNENKEI-------------VQGH--- 219 I E + G N+ L C + +I+W K VQG Sbjct: 3 IIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQG 62 Query: 220 ----RHRVLANGDLLISEIKWEDMGNYKCIAR-----NVVGKDTADTFVYPVLN 264 ++ L + + + I + D G Y C A N T V P ++ Sbjct: 63 RVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVS 116 >3O4O-C nrPDB Length = 339 Score = 44.5 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 26/182 (14%), Positives = 59/182 (32%), Gaps = 23/182 (12%) Query: 72 DGATIEIVCE-------MMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124 +G + + C S ++ W R+ + ++ A++ ++ Sbjct: 32 EGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQE 91 Query: 125 HIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHL 184 ++ TY C R S S + ++ + P P+I+ + + Sbjct: 92 --------DSGTYVCTTRNASYCDKMSIELRVFENT----DAFLPFISYPQILTLSTSGV 139 Query: 185 DLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRH-RVLANGDLLISEIKWEDMGNYK 243 + L + +I W + + V LL+ ++ ED G Y+ Sbjct: 140 LVCPD---LSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYR 196 Query: 244 CI 245 C+ Sbjct: 197 CV 198 Score = 40.3 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 29/83 (34%), Gaps = 9/83 (10%) Query: 186 LMGSNIQLPC-------RVHARPRAEITWLNNENKEIVQGHRHRVL--ANGDLLISEIKW 236 L G + L C PR +TW N++ V G + +G L + Sbjct: 31 LEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQ 90 Query: 237 EDMGNYKCIARNVVGKDTADTFV 259 ED G Y C RN D + Sbjct: 91 EDSGTYVCTTRNASYCDKMSIEL 113 >2IFG-A nrPDB Length = 347 Score = 42.6 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 29/201 (14%), Positives = 67/201 (33%), Gaps = 36/201 (17%) Query: 67 KLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHI 126 G + + C++ G + W++ L E + +++ Sbjct: 167 NASVDVGDDVLLRCQVEGRGLEQAGWILTEL---------------EQSATVMKSGGLPS 211 Query: 127 IDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDL 186 + L+ T + T +A V S + ++P + + + Sbjct: 212 LGLTLA---NVTSDLNRKNVTCWAENDVGRAEVS-VQVNVSFPASVQLH--------TAV 259 Query: 187 MGSNIQLPCRVHARPRAEITWLNNENK---------EIVQGHRHRVLANGDLLISEIKWE 237 + +P V +P + WL N + E ++ + + +G L +++ Sbjct: 260 EMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHV 319 Query: 238 DMGNYKCIARNVVGKDTADTF 258 + GNY +A N G+ +A Sbjct: 320 NNGNYTLLAANPFGQASASIM 340 >3KHO-B nrPDB Length = 133 Score = 42.6 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 33/97 (34%), Gaps = 10/97 (10%) Query: 157 PRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNEN---- 212 P + + G+ +I + S ++ C +TW Sbjct: 1 PAMTSSDLPLNFQGSPCSQIWQHPRFAAKKRSSMVKFHCYT--NHSGALTWFRKRGSQQP 58 Query: 213 KEIV-QGHRHRVLANGD---LLISEIKWEDMGNYKCI 245 +E+V + R NG L I I++ED G Y C Sbjct: 59 QELVSEEGRIVQTQNGSVYTLTIQNIQYEDNGIYFCK 95 >4V2A-A nrPDB Length = 303 Score = 42.2 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Query: 189 SNIQLPCRV-HARPRAEITWLNNEN-KEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIA 246 I LPCR P AE+ WL NE+ + + L++ + + D NY C+A Sbjct: 164 QGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREHSLVVRQARLADTANYTCVA 223 Query: 247 RNVVGKD 253 +N+V + Sbjct: 224 KNIVARR 230 >1WWC-A nrPDB Length = 118 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 35/91 (38%), Gaps = 10/91 (10%) Query: 177 IYTEKTHLDLMGSNIQLPCR----VHARPRAEITWLNNENK------EIVQGHRHRVLAN 226 +Y + L ++L V P + WL+N V+ ++ ++ Sbjct: 5 VYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISE 64 Query: 227 GDLLISEIKWEDMGNYKCIARNVVGKDTADT 257 G LL ++ + GNY IA+N +G Sbjct: 65 GCLLFNKPTHYNNGNYTLIAKNPLGTANQTI 95 Score = 30.3 bits (66), Expect = 0.90, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 30/79 (37%), Gaps = 10/79 (12%) Query: 76 IEIVCEMMGSQVPSIQWVVGHLPRSELDDL--DSNQVAEEAPSAIVRVRSSHIIDHVLSE 133 IE V + G+ P++ W+ P E + + Q E + ++ + +H + Sbjct: 25 IEFV--VRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNN----- 77 Query: 134 ARTYTCVGRTGSKTIYAST 152 YT + + T + Sbjct: 78 -GNYTLIAKNPLGTANQTI 95 >1FSK-B nrPDB Length = 214 Score = 41.1 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 34/85 (40%), Gaps = 16/85 (18%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLN---NENKEIV---QGHRHRVLANG-- 227 + + K+ +G + L C+ + W +++ +++ +R+ + + Sbjct: 4 LTQSPKSMSVSVGERVTLSCKASENVDTYVFWFQQKPDQSPKLLLYGPSNRYTGVPDRFT 63 Query: 228 --------DLLISEIKWEDMGNYKC 244 L IS ++ ED+ +Y C Sbjct: 64 GSGSTTDFTLTISSVQAEDLADYHC 88 >4MYW-B nrPDB Length = 331 Score = 41.1 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 34/208 (16%), Positives = 61/208 (29%), Gaps = 28/208 (13%) Query: 56 DWLKFTKTPPTKLQQADGATIEIVC-EMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEA 114 +W++ T+ + D + C G + W +E ++ + Sbjct: 133 NWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEI---RNPNGT 189 Query: 115 PSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKP 174 + I R Y V + + +V+ R T +P Sbjct: 190 VTVISR----------------YRLVPSREAHQQSLACIVNY-HMDRFKESLTLNVQYEP 232 Query: 175 RI-IYTEKTHLDLMGSNIQLPCRVHARPRA-EITWLNNENKEIVQGHRHRVLANGDLLIS 232 + I + L +++L C+ A P A E W + N L Sbjct: 233 EVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLP----KGVEAQNRTLFFK 288 Query: 233 E-IKWEDMGNYKCIARNVVGKDTADTFV 259 I + G Y C A N +G + V Sbjct: 289 GPINYSLAGTYICEATNPIGTRSGQVEV 316 Score = 31.0 bits (68), Expect = 0.51, Method: Composition-based stats. Identities = 21/116 (18%), Positives = 41/116 (35%), Gaps = 27/116 (23%) Query: 170 GAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI-----TWLNNENKE---------- 214 G +++ + +G+++ L C A P + TW + N Sbjct: 11 GRDPSQVVQVNDSMYGFIGTDVVLHC-SFANPLPSVKITQVTWQKSTNGSKQNVAIYNPS 69 Query: 215 ----IVQGHRHRV------LANGDLLISEIKWEDMGNYKCI-ARNVVGKDTADTFV 259 ++ +R RV +G + +S ++ ED G Y C A G + + Sbjct: 70 MGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNL 125 >2L7J-A nrPDB Length = 95 Score = 40.7 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 32/95 (33%), Gaps = 7/95 (7%) Query: 168 YPGAQKPRI-IYTEKTHLDLMGSNIQLPCRVHARPRA-EITWLNNENKEIVQGHRHRVLA 225 +P + I + L ++++L C+ A P A E W + Sbjct: 1 LNVQYEPEVTIEGFDGNWYLQRTDVKLTCKADANPPATEYHWTTLNGSLP----KGVEAQ 56 Query: 226 NGDLLISE-IKWEDMGNYKCIARNVVGKDTADTFV 259 N L I + G Y C A N +G + V Sbjct: 57 NRTLFFRGPITYSLAGTYICEATNPIGTRSGQVEV 91 >4LLY-B nrPDB Length = 212 Score = 40.3 bits (92), Expect = 9e-04, Method: Composition-based stats. Identities = 29/201 (14%), Positives = 57/201 (28%), Gaps = 25/201 (12%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQW---VVGHLPRSELDDLDSNQVAEEAPSAIVRV 121 P+ L + G + I C+ + W G P+ + + + Sbjct: 8 PSSLSASVGDRVTITCKASQDVSIGVAWYQDKPGKAPKLLIYSASYRYTGVPSRFSGSGS 67 Query: 122 R---SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178 + I + TY C IY T + K P + Sbjct: 68 GTDFTLTISSLQPEDFATYYC----QQYYIYPYTFGQGTKVEIKGQPK-----AAPSVTL 118 Query: 179 TEKTHLDLMGSNIQLPCRVHA-RPRA-EITWLNNENKEI--VQGHRHRVLANGD------ 228 + +L + L C + P A + W + + V+ +N Sbjct: 119 FPPSSEELQANKATLVCYISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAAWSY 178 Query: 229 LLISEIKWEDMGNYKCIARNV 249 L ++ +W+ +Y C + Sbjct: 179 LSLTPEQWKSHRSYSCQVTHE 199 Score = 33.7 bits (75), Expect = 0.087, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 32/103 (31%), Gaps = 26/103 (25%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ + + +G + + C+ + W ++ + + R Sbjct: 3 QMTQSPSSLSASVGDRVTITCKASQDVSIGVAWYQDKPGKAPKLLIYSASYRYTGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCIARNVVGKDTADTFVYP 261 +G L IS ++ ED Y C ++YP Sbjct: 63 SGSGSGTDFTLTISSLQPEDFATYYCQ----------QYYIYP 95 >4DEP-B nrPDB Length = 321 Score = 39.9 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 30/192 (15%), Positives = 56/192 (29%), Gaps = 38/192 (19%) Query: 89 SIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSK-- 146 +I W + S + V + + ++ Y CV R S Sbjct: 39 TITWYKDDSKTPVSTEQASRIHQHKEKLWFVPAK--------VEDSGHYYCVVRNSSYCL 90 Query: 147 --TIYASTVVHPP--------RSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCR 196 I A V + P + P G P + + + + Sbjct: 91 RIKISAKFVENEPNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKNEN------------- 137 Query: 197 VHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIAR-NVVGKDTA 255 ++ W + K ++ + H L++ + + GNY C A +GK Sbjct: 138 ---NELPKLQWYK-DCKPLLLDNIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYP 193 Query: 256 DTFVYPVLNEED 267 T V + E+ Sbjct: 194 ITRVIEFITLEE 205 >5MO9-X nrPDB Length = 151 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 25/70 (35%), Gaps = 11/70 (15%) Query: 197 VHARPRAEITWLNNENKEIVQGHRHRVLA---------NGDLLISEIKWEDMGNYKCIAR 247 V P+ + W N I+ ++ +G L + + G+Y IA+ Sbjct: 32 VKGNPKPALQWFYNGA--ILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAK 89 Query: 248 NVVGKDTADT 257 N GKD Sbjct: 90 NEYGKDEKQI 99 >1HCF-X nrPDB Length = 101 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 25/70 (35%), Gaps = 11/70 (15%) Query: 197 VHARPRAEITWLNNENKEIVQGHRHRVLA---------NGDLLISEIKWEDMGNYKCIAR 247 V P+ + W N I+ ++ +G L + + G+Y IA+ Sbjct: 25 VKGNPKPALQWFYNGA--ILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAK 82 Query: 248 NVVGKDTADT 257 N GKD Sbjct: 83 NEYGKDEKQI 92 >1CT8-A nrPDB Length = 214 Score = 39.1 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 27/211 (12%), Positives = 53/211 (25%), Gaps = 32/211 (15%) Query: 58 LKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQW---VVGHLPRS--ELDDLDSNQVAE 112 L T+TP T L G ++ + C S + W PR + + Sbjct: 2 LVMTQTPAT-LSVTPGDSVSLSCRASQSVSNKLHWYQQKSHESPRLLIKFASQSIPGIPS 60 Query: 113 EAPSAIVRVR-SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGA 171 + + I + Y C G L Sbjct: 61 RFSGSGSGSDFTLSINSVETEDFGIYFCHQTHG-----RPLTFGAGTKLELKR-----AD 110 Query: 172 QKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEI-----------VQG 218 P + + L + C ++ +I W + ++ + Sbjct: 111 AAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKD 170 Query: 219 HRHRVLANGDLLISEIKWEDMGNYKCIARNV 249 + + + L E + + Y C A + Sbjct: 171 STYSMSSTLTLTKDEYERHNS--YTCEATHK 199 >2NCM-A nrPDB Length = 99 Score = 39.1 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 31/82 (37%), Gaps = 9/82 (10%) Query: 188 GSNIQLPCRVHARP-RAEITWLNNENKEIVQGHRHRVL-----ANGDLLISEIKWEDMGN 241 G + C+V +I+W + +++ + + + L I +D G Sbjct: 17 GESKFFLCQVAGDAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGI 76 Query: 242 YKCIARNVVG---KDTADTFVY 260 YKC+ G + T + ++ Sbjct: 77 YKCVVTAEDGTQSEATVNVKIF 98 Score = 35.7 bits (80), Expect = 0.023, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 35/90 (38%), Gaps = 6/90 (6%) Query: 65 PTKLQQADGATIEIVCEMMGSQV-PSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRS 123 P++ + + G + +C++ G I W + + + + V + S+ + Sbjct: 9 PSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLT--- 65 Query: 124 SHIIDHVLSEARTYTCVGRTGSKTIYASTV 153 I + + +A Y CV T +TV Sbjct: 66 --IYNANIDDAGIYKCVVTAEDGTQSEATV 93 >4BSJ-A nrPDB Length = 232 Score = 39.1 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 30/97 (30%), Gaps = 10/97 (10%) Query: 172 QKPRIIYTEKTHLDLMGSN----IQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG 227 P I L + ++LP ++ A P E W + + H Sbjct: 2 HNPFISVEWLKGPILEATAGDELVKLPVKLAAYPPPEFQWYKDGKALSGRHSPHA----- 56 Query: 228 DLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLN 264 L++ E+ G Y N + + V+N Sbjct: 57 -LVLKEVTEASTGTYTLALWNSAAGLRRNISLELVVN 92 >4AIZ-B nrPDB Length = 108 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 28/90 (31%), Gaps = 16/90 (17%) Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAEITWL-------------NNENKEIVQGHRHRVLA 225 + G ++ C A P+ W + + R + Sbjct: 6 QPPSVSVSPGQTARITCSGDALPKQYAYWYQQKPGQAPVLVIYKDSERPSGIPERFSGSS 65 Query: 226 NGD---LLISEIKWEDMGNYKCIARNVVGK 252 +G L IS ++ ED +Y C + + G Sbjct: 66 SGTTVTLTISGVQAEDEADYYCQSADSSGT 95 >1HNG-A nrPDB Length = 176 Score = 38.4 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 19/46 (41%) Query: 208 LNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKD 253 + K ++ +LANGDL I + +D G Y + G Sbjct: 42 FKRKMKPFLKSGAFEILANGDLKIKNLTRDDSGTYNVTVYSTNGTR 87 >1WEJ-L nrPDB Length = 214 Score = 38.4 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 29/87 (33%), Gaps = 16/87 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ + + +G + + CR + W + + Q R Sbjct: 3 QMTQSPASLSASVGETVTITCRASGNIHNYLAWYQQKQGKSPQLLVYNAKTLADGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCI 245 +G L I+ ++ ED G+Y C Sbjct: 63 SGSGSGTQYSLKINSLQPEDFGSYYCQ 89 Score = 38.0 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 30/211 (14%), Positives = 64/211 (30%), Gaps = 32/211 (15%) Query: 58 LKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRS-ELDDLDSNQVAEEAPS 116 ++ T++P + L + G T+ I C G+ + W +S +L ++ +A+ PS Sbjct: 2 IQMTQSPAS-LSASVGETVTITCRASGNIHNYLAWYQQKQGKSPQLLVYNAKTLADGVPS 60 Query: 117 AIVRVR-----SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGA 171 S I + +Y C P T + Sbjct: 61 RFSGSGSGTQYSLKINSLQPEDFGSYYC----------QHFWSTPWTFGGGTKLEIKRAD 110 Query: 172 QKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEI-----------VQG 218 P + + L + C ++ +I W + ++ + Sbjct: 111 AAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKD 170 Query: 219 HRHRVLANGDLLISEIKWEDMGNYKCIARNV 249 + + + L E + + Y C A + Sbjct: 171 STYSMSSTLTLTKDEYERHNS--YTCEATHK 199 >5VF3-Z nrPDB Length = 376 Score = 38.0 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 33/207 (15%), Positives = 58/207 (28%), Gaps = 31/207 (14%) Query: 63 TPPTKLQQADGATIEIVCEMMGSQ---VPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIV 119 TP + G ++ + + QW V D +QV E Sbjct: 102 TPASPAAGVIGTPVQFTAALASQPDGASATYQWYV-----------DDSQVGGET----- 145 Query: 120 RVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYT 179 S+ S + CV + + T Y + V S +KT P++ T Sbjct: 146 --NSTFSYTPTTSGVKRIKCVAQV-TATDYDALSVTSNEVSLTVNKKTMN----PQVTLT 198 Query: 180 EKTHLDLMGSNIQLPCRVHARPRAE---ITWLNNENKEIVQGHRHRV--LANGDLLISEI 234 + ++ V P +W + + + + V + G I Sbjct: 199 PPSINVQQDASATFTANVTGAPEEAQITYSWKKDSSPVEGSTNVYTVDTSSVGSQTIEVT 258 Query: 235 KWEDMGNYKCIARNVVGKDTADTFVYP 261 +Y + G T V P Sbjct: 259 ATVTAADYNPVTVTKTGNVTVTAKVAP 285 >3O3U-N nrPDB Length = 581 Score = 38.0 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 27/117 (23%), Positives = 44/117 (37%), Gaps = 12/117 (10%) Query: 152 TVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCR-VHARPRAEITWL-- 208 T V S R T + AQ + + +G + L C+ +P + W Sbjct: 345 TAVINAASGRQTVDAALAAAQTNAAAASAQNITARIGEPLVLKCKGAPKKPPQRLEWKLN 404 Query: 209 --NNENKEIVQ-------GHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTAD 256 E +++ RVL NG L + + +D G ++C A N GK+T Sbjct: 405 TGRTEAWKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKS 461 Score = 34.9 bits (78), Expect = 0.035, Method: Composition-based stats. Identities = 19/164 (11%), Positives = 48/164 (29%), Gaps = 19/164 (11%) Query: 66 TKLQQADGATIEIVCE-MMGSQVPSIQWVVGHLPRSELDDLDSNQV-AEEAPSAIVRVRS 123 + G + + C+ ++W + L ++ + ++ S Sbjct: 374 QNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGGGPWDSVARVLPNGS 433 Query: 124 SHIIDHVLSEARTYTCVG--RTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEK 181 + + + + C R G +T V + Y KP I+ + Sbjct: 434 LFLPAVGIQDEGIFRCQAMNRNGKETKSNYRV------------RVYQIPGKPEIVDSAS 481 Query: 182 THLDLMGSNIQLPCRVHA-RPRAEITWLNNENKEIVQGHRHRVL 224 + + + C P ++W + K +V + + Sbjct: 482 ELTAGVPNKVG-TCVSEGSYPAGTLSWHLDG-KPLVPNEKGVSV 523 >1A7O-L nrPDB Length = 106 Score = 38.0 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 28/86 (32%), Gaps = 16/86 (18%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRHR 222 + + + +G + + CR + W + + Q R Sbjct: 4 LTQSPASLSASVGETVTITCRASGNIHNYLAWYQQKQGKSPQLLVYYTTTLADGVPSRFS 63 Query: 223 VLANG---DLLISEIKWEDMGNYKCI 245 +G L I+ ++ +D G+Y C Sbjct: 64 GSGSGTQYSLKINSLQPDDFGSYYCQ 89 Score = 29.9 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 26/81 (32%), Gaps = 6/81 (7%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQW---VVGHLPRSEL---DDLDSNQVAEEAPSAI 118 P L + G T+ I C G+ + W G P+ + L + + S Sbjct: 8 PASLSASVGETVTITCRASGNIHNYLAWYQQKQGKSPQLLVYYTTTLADGVPSRFSGSGS 67 Query: 119 VRVRSSHIIDHVLSEARTYTC 139 S I + +Y C Sbjct: 68 GTQYSLKINSLQPDDFGSYYC 88 >1DVF-C nrPDB Length = 107 Score = 37.6 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 30/92 (32%), Gaps = 16/92 (17%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ + + +G + + CR + W + V+ R Sbjct: 3 QLTQSPSSLSASLGDRVTISCRASQDISNYLNWYQQKPDGTVKLLIYYTSRLHSGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCIARNVV 250 +G L IS ++ ED+ Y C N + Sbjct: 63 SGSGSGTDYSLTISNLEQEDIATYFCQQGNTL 94 >1VCA-A nrPDB Length = 202 Score = 37.2 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 31/198 (15%), Positives = 64/198 (32%), Gaps = 34/198 (17%) Query: 58 LKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSA 117 K TP ++ G ++ + C G + P W R+++D + +V E ++ Sbjct: 1 FKIETTPESRYLAQIGDSVSLTCSTTGCESPFFSW------RTQIDSPLNGKVTNEGTTS 54 Query: 118 IVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRII 177 + + +Y C S+ + V ++P + + Sbjct: 55 TLTMNP-----VSFGNEHSYLCTATCESRKLEKGIQVEI---------YSFPKDPEIHL- 99 Query: 178 YTEKTHLDLMGSNIQLPCRVHA-RP--RAEITWLNNE----NKEIVQGHRHRVLANGDL- 229 + G I + C V P R EI L + ++E ++ + L L Sbjct: 100 ----SGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLE 155 Query: 230 -LISEIKWEDMGNYKCIA 246 + + + C A Sbjct: 156 VTFTPVIEDIGKVLVCRA 173 >1MLC-A nrPDB Length = 214 Score = 37.2 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 26/211 (12%), Positives = 58/211 (27%), Gaps = 32/211 (15%) Query: 58 LKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQW---VVGHLPRS--ELDDLDSNQVAE 112 ++ T++P T L G ++ + C S ++ W PR + S+ + Sbjct: 2 IELTQSPAT-LSVTPGDSVSLSCRASQSISNNLHWYQQKSHESPRLLIKYVSQSSSGIPS 60 Query: 113 EAPSAIVRVR-SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGA 171 + + I + Y C P T + Sbjct: 61 RFSGSGSGTDFTLSINSVETEDFGMYFCQQSNS----------WPRTFGGGTKLEIKRAD 110 Query: 172 QKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEI-----------VQG 218 P + + L + C ++ +I W + ++ + Sbjct: 111 AAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKD 170 Query: 219 HRHRVLANGDLLISEIKWEDMGNYKCIARNV 249 + + + L E + + Y C A + Sbjct: 171 STYSMSSTLTLTKDEYERHNS--YTCEATHK 199 >1A0Q-L nrPDB Length = 212 Score = 36.4 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 29/205 (14%), Positives = 56/205 (27%), Gaps = 34/205 (16%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSE------LDDLDSNQVAEEAP-SA 117 P+ L + G + I C+ I W H P + + S Sbjct: 8 PSSLSASLGGKVTITCKASQDIKKYIGW-YQHKPGKQPRLLIHYTSTLLPGIPSRFRGSG 66 Query: 118 IVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRII 177 R S I + + TY C+ +T T + R P + Sbjct: 67 SGRDYSFSISNLEPEDIATYYCLQYYNLRTFGGGTKLEIKR-----------ADAAPTVS 115 Query: 178 YTEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEI-----------VQGHRHRVL 224 + L + C ++ +I W + ++ + + + Sbjct: 116 IFPPSSEQLTSGGASVVCFLNNFYSKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMS 175 Query: 225 ANGDLLISEIKWEDMGNYKCIARNV 249 + L E + + Y C A + Sbjct: 176 STLTLTKDEYERHNS--YTCEATHK 198 Score = 30.7 bits (67), Expect = 0.67, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 31/85 (36%), Gaps = 16/85 (18%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKE-----------IVQG--HRHR 222 + + + +G + + C+ + I W ++ + ++ G R R Sbjct: 4 LTQSPSSLSASLGGKVTITCKASQDIKKYIGWYQHKPGKQPRLLIHYTSTLLPGIPSRFR 63 Query: 223 VLANG---DLLISEIKWEDMGNYKC 244 +G IS ++ ED+ Y C Sbjct: 64 GSGSGRDYSFSISNLEPEDIATYYC 88 >1SVZ-A nrPDB Length = 247 Score = 36.1 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 21/163 (12%), Positives = 41/163 (25%), Gaps = 28/163 (17%) Query: 123 SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKT 182 + I + Y C + + + + G + Sbjct: 77 TLKISRVEAEDLGIYYCFQGSHFPPTFGGGTKLEIKGGGGSGGGGSGGGGSEVQLQQSGP 136 Query: 183 HLDLMGSNIQLPCRVHARPRAEIT----------------WLNNENKEIVQGHRHR---- 222 L G +++ C+ + + W+N E E + Sbjct: 137 ELKKPGETVKISCKATNYAFTDYSMHWVKQAPGGDLKYVGWINTETDEPTFADDFKGRFA 196 Query: 223 -----VLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVY 260 + L I+ +K ED Y C+ D + F Y Sbjct: 197 FSLDTSTSTAFLQINNLKNEDTATYFCVRDR---HDYGEIFTY 236 >1KCU-L nrPDB Length = 214 Score = 36.1 bits (81), Expect = 0.016, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 36/103 (34%), Gaps = 26/103 (25%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWL--NNENKEIV----QGHRHRVLANG-- 227 + + K+ +G + L C+ ++W E + +R+ + + Sbjct: 4 LTQSPKSMSMSVGEKVTLSCKASENVDTYVSWYQQRPEQPPALLIYGASNRYTGVPDRFT 63 Query: 228 --------DLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPV 262 L IS ++ ED+ +Y C ++ YP+ Sbjct: 64 GSGSATDFTLTISSVQAEDLADYHC----------GQSYSYPL 96 >5VI4-C nrPDB Length = 339 Score = 36.1 bits (81), Expect = 0.018, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 42/148 (28%), Gaps = 25/148 (16%) Query: 132 SEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLM---G 188 S YTCV + P P IY+ + G Sbjct: 188 SNNGQYTCVVTYPENGRLFHL-----TRTVTVKVVGSPKDALPPQIYSPNDRVVYEKEPG 242 Query: 189 SNIQLPCRVHAR----PRAEITWLNNENKE------------IVQGHRHRVLANGDLLIS 232 + +PC+V+ E+ W + K + L I Sbjct: 243 EELVIPCKVYFSFIMDSHNEVWWTIDGKKPDDVTVDITINESVSYSSTEDETRTQILSIK 302 Query: 233 EIKWEDMG-NYKCIARNVVGKDTADTFV 259 ++ ED+ NY C ARN G+ V Sbjct: 303 KVTPEDLRRNYVCHARNTKGEAEQAAKV 330 >1F6L-L nrPDB Length = 114 Score = 36.1 bits (81), Expect = 0.018, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 32/87 (36%), Gaps = 16/87 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKE-----------IVQG--HRH 221 ++ + + +G + + CR + + W + + + +G R Sbjct: 3 QMTQSPASLSASVGETVTITCRASENIYSYLAWYQQKQGKSPQLLVYNAKTLAEGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCI 245 +G L I+ ++ ED G+Y C Sbjct: 63 SGSGSGTQFSLKINSLQPEDFGSYYCQ 89 Score = 29.9 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 38/100 (38%), Gaps = 7/100 (7%) Query: 58 LKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRS-ELDDLDSNQVAEEAPS 116 ++ T++P + L + G T+ I C + + W +S +L ++ +AE PS Sbjct: 2 IQMTQSPAS-LSASVGETVTITCRASENIYSYLAWYQQKQGKSPQLLVYNAKTLAEGVPS 60 Query: 117 AIVRVR-----SSHIIDHVLSEARTYTCVGRTGSKTIYAS 151 S I + +Y C G+ + S Sbjct: 61 RFSGSGSGTQFSLKINSLQPEDFGSYYCQHHYGTPFTFGS 100 >1D5B-A nrPDB Length = 211 Score = 36.1 bits (81), Expect = 0.018, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 31/86 (36%), Gaps = 16/86 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQG-------------HRH 221 ++ + + +G + + C+ + + W + + + R Sbjct: 3 KMTQSPSSMYASLGERVTITCKASQDINSYLNWFQQKPGKSPKTLIYRTNRLVDGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKC 244 +G L IS +++EDMG Y C Sbjct: 63 SGSGSGQDYSLTISSLEYEDMGIYYC 88 >3F7V-B nrPDB Length = 212 Score = 36.1 bits (81), Expect = 0.019, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 26/77 (33%), Gaps = 16/77 (20%) Query: 188 GSNIQLPCRVHARPRAEITWLN---NENKEIVQG----------HRHRVLANGD---LLI 231 G + CR +I W N + ++ R +G L I Sbjct: 16 GERVSFSCRASQSIGTDIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSI 75 Query: 232 SEIKWEDMGNYKCIARN 248 + ++ ED+ NY C N Sbjct: 76 NSVESEDIANYYCQQSN 92 Score = 30.7 bits (67), Expect = 0.74, Method: Composition-based stats. Identities = 27/204 (13%), Positives = 51/204 (25%), Gaps = 31/204 (15%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRS-ELDDLDSNQVAEEAPSAIVRVRS 123 P L + G + C S I W S L +++ PS S Sbjct: 8 PAILSVSPGERVSFSCRASQSIGTDIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGS 67 Query: 124 -----SHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178 I + Y C + S T + P + Sbjct: 68 GTDFTLSINSVESEDIANYYCQQSNRWPFTFGS----------GTKLEIKRADAAPTVSI 117 Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEI-----------VQGHRHRVLA 225 + L + C ++ +I W + ++ + + + + Sbjct: 118 FPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSS 177 Query: 226 NGDLLISEIKWEDMGNYKCIARNV 249 L E + + Y C A + Sbjct: 178 TLTLTKDEYERHNS--YTCEATHK 199 >4D3C-L nrPDB Length = 215 Score = 35.7 bits (80), Expect = 0.020, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 38/125 (30%), Gaps = 31/125 (24%) Query: 173 KPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GH 219 + + T + +G + + C+ + W + + + Sbjct: 1 ELDLTQTPSSVSAAVGGTVTINCQASQSVSNLLAWYQQKPGQPPKLLIYGASNLESGVPS 60 Query: 220 RHRVLANG---DLLISEIKWEDMGNYKCI-------ARNVVGKDTA--------DTFVYP 261 R R +G L IS +K ED Y C A G + F++P Sbjct: 61 RFRGSGSGTEFTLTISGMKAEDAATYYCQSGYYSAGATFGAGTNVEIKRTVAAPSVFIFP 120 Query: 262 VLNEE 266 +E+ Sbjct: 121 PSDEQ 125 Score = 34.9 bits (78), Expect = 0.039, Method: Composition-based stats. Identities = 36/209 (17%), Positives = 62/209 (29%), Gaps = 31/209 (14%) Query: 58 LKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSA 117 L T+T P+ + A G T+ I C+ S + W P L E+ Sbjct: 2 LDLTQT-PSSVSAAVGGTVTINCQASQSVSNLLAW-YQQKPGQPPKLLIYGASNLESGVP 59 Query: 118 IVRVRS-------SHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPG 170 S I +A TY C ++G + A+ + T Sbjct: 60 SRFRGSGSGTEFTLTISGMKAEDAATYYC--QSGYYSAGATFGAGTNVEIKRTVAA---- 113 Query: 171 AQKPRIIYTEKTHLDLMGSNIQLPCRVHA-RP-RAEITWLNNENKEIVQGHRHRVLA--- 225 P + + L + C ++ P A++ W +N + V Sbjct: 114 ---PSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQW-KVDNALQSGNSQESVTEQDS 169 Query: 226 -------NGDLLISEIKWEDMGNYKCIAR 247 + L +S+ +E Y C Sbjct: 170 KDSTYSLSSTLTLSKADYEKHKVYACEVT 198 >1E4W-L nrPDB Length = 214 Score = 35.7 bits (80), Expect = 0.021, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 28/87 (32%), Gaps = 16/87 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ T + +G + + CR + W + V+ R Sbjct: 3 QMTQTPSSLSASLGDRVTISCRASQDISHYLNWFQQKPDGTVKLLIYYTSTLHSGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCI 245 +G L IS ++ ED+ Y C Sbjct: 63 SGSGSGTDYSLTISNLEEEDIAFYFCQ 89 Score = 32.6 bits (72), Expect = 0.18, Method: Composition-based stats. Identities = 26/212 (12%), Positives = 53/212 (25%), Gaps = 34/212 (16%) Query: 58 LKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSA 117 ++ T+T P+ L + G + I C + W P + L + Sbjct: 2 IQMTQT-PSSLSASLGDRVTISCRASQDISHYLNW-FQQKPDGTVKLLIYYTSTLHSGVP 59 Query: 118 IVRVR-------SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPG 170 S I + + Y C P T Sbjct: 60 SRFSGSGSGTDYSLTISNLEEEDIAFYFC----------QQGGALPFTFGSGTKLAIKRA 109 Query: 171 AQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEI-----------VQ 217 P + + L + C ++ +I W + ++ + Sbjct: 110 DAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLDSWTDQDSK 169 Query: 218 GHRHRVLANGDLLISEIKWEDMGNYKCIARNV 249 + + + L E + + Y C A + Sbjct: 170 DSTYSMSSTLTLTKDEYERHNS--YTCEATHK 199 >5XCV-B nrPDB Length = 165 Score = 35.7 bits (80), Expect = 0.022, Method: Composition-based stats. Identities = 14/95 (14%), Positives = 29/95 (30%), Gaps = 20/95 (21%) Query: 170 GAQKPRIIYTEKTHLDLMGSNIQLPC-RVHAR--------------PRAEITWLNNE--- 211 G+ ++ + +GS ++L C R ++ Sbjct: 1 GSHMQFVLTQPNSVSTNLGSTVKLSCKRSTGNIGSNYVNWYQQHEGRSPTTMIYRDDKRP 60 Query: 212 --NKEIVQGHRHRVLANGDLLISEIKWEDMGNYKC 244 + G R + L I+ ++ ED +Y C Sbjct: 61 DGVPDRFSGSIDRSSNSALLTINNVQTEDEADYFC 95 >3MJ9-A nrPDB Length = 268 Score = 35.3 bits (79), Expect = 0.026, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 42/128 (32%), Gaps = 19/128 (14%) Query: 65 PTKLQQADGATIEIVCEMMGSQ---VPSIQWVVGHLPRSELDDL---DSNQVAEEAPSA- 117 P L+ G T ++ C + ++ V + W+ +E + + DSN + + S Sbjct: 125 PRDLRVRVGDTTQMRCSIQSTEEKRVTKVNWMFSSGSHTEEETVLSYDSNMRSGKFQSLG 184 Query: 118 -----------IVRV-RSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPE 165 I R S + S+ YTC G + V+H + Sbjct: 185 RFRNRVDLTGDISRNDGSIKLQTVKESDQGIYTCSIYVGKLESRKTIVLHVVQDEFQRTI 244 Query: 166 KTYPGAQK 173 P K Sbjct: 245 SPTPPTDK 252 Score = 32.6 bits (72), Expect = 0.20, Method: Composition-based stats. Identities = 23/152 (15%), Positives = 43/152 (28%), Gaps = 46/152 (30%) Query: 122 RSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEK 181 S + D ++ YTC R ++ S V+ P + PE + Sbjct: 84 GSLLLQDVQKADEGIYTCEIRLKNE----SMVMKKPVELWVLPE-------------EPR 126 Query: 182 THLDLMGSNIQLPCRVHARPRAEIT---WLNNENKEIVQGHRHRVLAN------------ 226 +G Q+ C + + +T W+ + + +N Sbjct: 127 DLRVRVGDTTQMRCSIQSTEEKRVTKVNWMFSSGSHTEEETVLSYDSNMRSGKFQSLGRF 186 Query: 227 --------------GDLLISEIKWEDMGNYKC 244 G + + +K D G Y C Sbjct: 187 RNRVDLTGDISRNDGSIKLQTVKESDQGIYTC 218 >1QFW-M nrPDB Length = 108 Score = 35.3 bits (79), Expect = 0.028, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 33/85 (38%), Gaps = 16/85 (18%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLN---NENKEIV---QGHRHRVLANG-- 227 + + K+ +G + L C+ + ++W ++ +++ +R + + Sbjct: 4 LTQSPKSMSMSVGERVTLSCKASETVDSFVSWYQQKPEQSPKLLIFGASNRFSGVPDRFT 63 Query: 228 --------DLLISEIKWEDMGNYKC 244 L IS ++ ED +Y C Sbjct: 64 GSGSATDFTLTISSVQAEDFADYHC 88 >3S35-X nrPDB Length = 122 Score = 35.3 bits (79), Expect = 0.029, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 37/105 (35%), Gaps = 13/105 (12%) Query: 168 YPGAQKPRIIYTEKTHLDLM-GSNIQLPC--RVHARPRAEITWL----NNENKEIVQGHR 220 PG + ++ + ++L G + L C R + W +++K++V Sbjct: 2 DPGYRIYDVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDL 61 Query: 221 HRVLAN------GDLLISEIKWEDMGNYKCIARNVVGKDTADTFV 259 + L I + D G Y C A + + TFV Sbjct: 62 KTQSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFV 106 >2AEP-L nrPDB Length = 214 Score = 35.3 bits (79), Expect = 0.030, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 25/77 (32%), Gaps = 16/77 (20%) Query: 188 GSNIQLPCRVHARPRAEITWLNNEN----KEIVQGHRHRVLANGD------------LLI 231 G + + C+ + W + K ++ +R D L I Sbjct: 16 GDRVSVTCKASQNVGTNVAWYQKKPGQSPKPLMYSASYRYSGVPDRFTGSGSGTDFTLTI 75 Query: 232 SEIKWEDMGNYKCIARN 248 S ++ ED+ Y C N Sbjct: 76 SNVQSEDLAEYFCQQFN 92 >4Q6I-C nrPDB Length = 208 Score = 35.3 bits (79), Expect = 0.031, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 36/108 (33%), Gaps = 23/108 (21%) Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVL--------------- 224 +K L G ++L C + + W N N+ + G++ L Sbjct: 26 KKVVLGKKGDTVELTCTASQKKSIQFHW-KNSNQIKILGNQGSFLTKGPSKLNDRADSRR 84 Query: 225 -----ANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNEED 267 N L+I +K ED Y C + K+ V+ + D Sbjct: 85 SLWDQGNFPLIIKNLKIEDSDTYICEVEDQ--KEEVQLLVFGLTANSD 130 Score = 33.0 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 23/186 (12%), Positives = 49/186 (26%), Gaps = 49/186 (26%) Query: 73 GATIEIVCEMMGSQVPSIQWVVGHL--------------PRSELDDLDSNQVAEEAPSAI 118 G T+E+ C + W + P D DS + + + Sbjct: 34 GDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFP 93 Query: 119 VRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178 + +++ I ++ TY C + + + Sbjct: 94 LIIKNLKI-----EDSDTYICEVEDQKEEV---------QLLVFGLTAN----------- 128 Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWED 238 L G ++ L + + K I L +S+++ +D Sbjct: 129 --SDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNI--------QGGKTLSVSQLELQD 178 Query: 239 MGNYKC 244 G + C Sbjct: 179 SGTWTC 184 >3O2D-A nrPDB Length = 188 Score = 35.3 bits (79), Expect = 0.031, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 36/108 (33%), Gaps = 23/108 (21%) Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVL--------------- 224 +K L G ++L C + + W N N+ + G++ L Sbjct: 1 KKVVLGKKGDTVELTCTASQKKSIQFHW-KNSNQIKILGNQGSFLTKGPSKLNDRADSRR 59 Query: 225 -----ANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNEED 267 N L+I +K ED Y C + K+ V+ + D Sbjct: 60 SLWDQGNFPLIIKNLKIEDSDTYICEVEDQ--KEEVQLLVFGLTANSD 105 Score = 33.0 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 23/186 (12%), Positives = 49/186 (26%), Gaps = 49/186 (26%) Query: 73 GATIEIVCEMMGSQVPSIQWVVGHL--------------PRSELDDLDSNQVAEEAPSAI 118 G T+E+ C + W + P D DS + + + Sbjct: 9 GDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFP 68 Query: 119 VRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178 + +++ I ++ TY C + + + Sbjct: 69 LIIKNLKI-----EDSDTYICEVEDQKEEV---------QLLVFGLTAN----------- 103 Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWED 238 L G ++ L + + K I L +S+++ +D Sbjct: 104 --SDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNI--------QGGKTLSVSQLELQD 153 Query: 239 MGNYKC 244 G + C Sbjct: 154 SGTWTC 159 >1WIO-A nrPDB Length = 363 Score = 35.3 bits (79), Expect = 0.031, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 36/108 (33%), Gaps = 23/108 (21%) Query: 180 EKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVL--------------- 224 +K L G ++L C + + W N N+ + G++ L Sbjct: 1 KKVVLGKKGDTVELTCTASQKKSIQFHW-KNSNQIKILGNQGSFLTKGPSKLNDRADSRR 59 Query: 225 -----ANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNEED 267 N L+I +K ED Y C + K+ V+ + D Sbjct: 60 SLWDQGNFPLIIKNLKIEDSDTYICEVEDQ--KEEVQLLVFGLTANSD 105 Score = 33.0 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 23/186 (12%), Positives = 49/186 (26%), Gaps = 49/186 (26%) Query: 73 GATIEIVCEMMGSQVPSIQWVVGHL--------------PRSELDDLDSNQVAEEAPSAI 118 G T+E+ C + W + P D DS + + + Sbjct: 9 GDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFP 68 Query: 119 VRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178 + +++ I ++ TY C + + + Sbjct: 69 LIIKNLKI-----EDSDTYICEVEDQKEEV---------QLLVFGLTAN----------- 103 Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWED 238 L G ++ L + + K I L +S+++ +D Sbjct: 104 --SDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNI--------QGGKTLSVSQLELQD 153 Query: 239 MGNYKC 244 G + C Sbjct: 154 SGTWTC 159 >2XOT-A nrPDB Length = 361 Score = 34.9 bits (78), Expect = 0.040, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 28/63 (44%), Gaps = 1/63 (1%) Query: 185 DLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRV-LANGDLLISEIKWEDMGNYK 243 +G + + C + ++ + + + QG V + NGDL +++ ED G Y Sbjct: 258 AHLGDTLTIRCDTKQQGMTKVWVSPSNEQVLSQGSNGSVSVRNGDLFFKKVQVEDGGVYT 317 Query: 244 CIA 246 C A Sbjct: 318 CYA 320 Score = 29.5 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 22/139 (15%), Positives = 41/139 (29%), Gaps = 9/139 (6%) Query: 36 DVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVG 95 D + K + F D+ ++ + + G T+ I C+ + + WV Sbjct: 224 DFQEDLYCMHSKKLHNIFSLDFFNCSEYKESAWEAHLGDTLTIRCDTKQQGMTKV-WV-- 280 Query: 96 HLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVH 155 S ++ +Q S VR + + YTC + S + Sbjct: 281 ----SPSNEQVLSQ--GSNGSVSVRNGDLFFKKVQVEDGGVYTCYAMGETFNETLSVELK 334 Query: 156 PPRSSRLTPEKTYPGAQKP 174 + T A P Sbjct: 335 VYNFTLHGHHDTLNAAADP 353 >4CKD-L nrPDB Length = 107 Score = 34.9 bits (78), Expect = 0.041, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 31/90 (34%), Gaps = 16/90 (17%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNN---ENKEIVQG----------HRHR 222 + + T G+++ L CR ++ W E+ ++ R Sbjct: 4 LTQSPATLSVTPGNSVSLSCRASQSIGNDLHWYQQKSHESPRLLIKYASQSISGIPSRFS 63 Query: 223 VLANGD---LLISEIKWEDMGNYKCIARNV 249 +G L I+ ++ ED G Y C N Sbjct: 64 GSGSGTDFTLSINSVETEDFGMYFCQQSNS 93 >6FAB-L nrPDB Length = 214 Score = 34.9 bits (78), Expect = 0.042, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 29/92 (31%), Gaps = 16/92 (17%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ + +G + + CR + W + ++ R Sbjct: 3 QMTQIPSSLSASLGDRVSISCRASQDINNFLNWYQQKPDGTIKLLIYFTSRSQSGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCIARNVV 250 +G L IS ++ ED+ Y C N + Sbjct: 63 SGSGSGTDYSLTISNLEQEDIATYFCQQGNAL 94 Score = 34.5 bits (77), Expect = 0.049, Method: Composition-based stats. Identities = 25/205 (12%), Positives = 51/205 (24%), Gaps = 33/205 (16%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVR-- 122 P+ L + G + I C + W P + L ++ Sbjct: 8 PSSLSASLGDRVSISCRASQDINNFLNW-YQQKPDGTIKLLIYFTSRSQSGVPSRFSGSG 66 Query: 123 -----SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRII 177 S I + + TY C P T + P + Sbjct: 67 SGTDYSLTISNLEQEDIATYFCQQGNA----------LPRTFGGGTKLEIKRADAAPTVS 116 Query: 178 YTEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEI-----------VQGHRHRVL 224 + L + C ++ +I W + ++ + + + Sbjct: 117 IFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMS 176 Query: 225 ANGDLLISEIKWEDMGNYKCIARNV 249 + L E + + Y C A + Sbjct: 177 STLTLTKDEYERHNS--YTCEATHK 199 >1KCR-L nrPDB Length = 213 Score = 34.9 bits (78), Expect = 0.042, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 38/104 (36%), Gaps = 26/104 (25%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLN---NENKEIV---QGHRHRVLANG-- 227 + + K+ +G + L C+ ++W ++ +++ +R+ + + Sbjct: 4 LTQSPKSMSMSVGERVTLSCKASENVGTYVSWYQQKPEQSPKLLIYGASNRYTGVPDRFT 63 Query: 228 --------DLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVL 263 L IS ++ ED+ +Y C T+ YP Sbjct: 64 GSGSATDFTLKISSVQAEDLADYHC----------GQTYSYPTF 97 >3KG5-A nrPDB Length = 134 Score = 34.5 bits (77), Expect = 0.043, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 38/101 (37%), Gaps = 16/101 (15%) Query: 157 PRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCR---VHARPRAEITWL----N 209 P + + G+ RI + + G +++ C ++WL Sbjct: 2 PAARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNSASGN----VSWLWKQEM 57 Query: 210 NENKEIVQGHRHRVLAN-----GDLLISEIKWEDMGNYKCI 245 +EN + ++ + R+ + L I I++ED G Y C Sbjct: 58 DENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNGIYFCQ 98 >3UEZ-A nrPDB Length = 208 Score = 34.5 bits (77), Expect = 0.043, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 29/97 (29%), Gaps = 18/97 (18%) Query: 124 SHIIDHVLSEARTYTCVGRTGSKTIYA--STVVHPPRSSRLTPEKTYPGAQKPRIIYTEK 181 + +S Y C + G + V P + + E++ Q P Sbjct: 69 LVVTAANISHDGNYLCRMKLGETEVTKQEHLSVVKPLTLSVHSERS----QFPDFSV--- 121 Query: 182 THLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQG 218 + + C V+A P + WL E E Sbjct: 122 ---------LTVTCTVNAFPHPHVQWLMPEGVEPAPS 149 >1CFS-A nrPDB Length = 214 Score = 34.5 bits (77), Expect = 0.049, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 32/86 (37%), Gaps = 16/86 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQG-------------HRH 221 ++ + + +G + + C+ + +TW + + + R Sbjct: 3 KMTQSPSSMYTSLGERVTITCKASQDINSFLTWFLQKPGKSPKTLIYRANRLMIGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKC 244 +G L IS +++EDMG Y C Sbjct: 63 SGSGSGQTYSLTISSLEYEDMGIYYC 88 >1KCS-L nrPDB Length = 214 Score = 34.5 bits (77), Expect = 0.049, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 30/83 (36%), Gaps = 16/83 (19%) Query: 178 YTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKE----IVQGHRHRVLANGD----- 228 + K+ +G + L C+ ++W + + ++ G +R D Sbjct: 6 QSPKSMGMSVGEAVTLNCKASENVGTYVSWYQQKPGQSPVLLIYGASNRYTGVPDRFTGS 65 Query: 229 -------LLISEIKWEDMGNYKC 244 L IS ++ +D +Y C Sbjct: 66 GSATDFTLTISSVQADDDADYYC 88 >5XCS-B nrPDB Length = 166 Score = 34.5 bits (77), Expect = 0.055, Method: Composition-based stats. Identities = 13/96 (13%), Positives = 29/96 (30%), Gaps = 22/96 (22%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVH------ARPRAEITWLNNENKEIVQ------GHRHRV 223 + + + G + + C+ + +TW + + + R Sbjct: 5 LTQSPSSLTVTAGEKVTMSCKSSQSLLNSGNQKNYLTWYQQKPGQPPKLLIYWASTRESG 64 Query: 224 LANG----------DLLISEIKWEDMGNYKCIARNV 249 + + L IS ++ ED+ Y C N Sbjct: 65 VPDRFTGSGSGRDFTLTISSVQAEDLAVYYCQNDNS 100 >1FBI-L nrPDB Length = 214 Score = 34.1 bits (76), Expect = 0.061, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 27/87 (31%), Gaps = 16/87 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ T + +G + + CR + W + V+ R Sbjct: 3 QMTQTTSSLSASLGDRVTISCRASQDISNYLNWYQKKPDGTVKLLIYYTSRLHSGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCI 245 +G L I ++ ED+ Y C Sbjct: 63 SGSGSGTDYSLTIRNLEQEDIATYFCQ 89 >1C12-A nrPDB Length = 214 Score = 34.1 bits (76), Expect = 0.066, Method: Composition-based stats. Identities = 28/204 (13%), Positives = 57/204 (27%), Gaps = 31/204 (15%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSEL------DDLDSNQVAEEAPSAI 118 P+ + + G T+ I C +I W+ +S +L+ + + S Sbjct: 8 PSSMSVSLGDTVSITCHASQGISSNIGWLQQKPGKSFKGLIYHGTNLEDGVPSRFSGSGS 67 Query: 119 VRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178 S I + Y CV V P T + P + Sbjct: 68 GADYSLTISSLESEDFADYYCV----------QYVQFPFTFGSGTKLEIKRADAAPTVSI 117 Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEI-----------VQGHRHRVLA 225 + L + C ++ +I W + ++ + + + + Sbjct: 118 FPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSS 177 Query: 226 NGDLLISEIKWEDMGNYKCIARNV 249 L E + + Y C A + Sbjct: 178 TLTLTKDEYERHNS--YTCEATHK 199 Score = 32.2 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 30/86 (34%), Gaps = 16/86 (18%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQG-------------HRHR 222 + + + +G + + C + I WL + + +G R Sbjct: 4 LTQSPSSMSVSLGDTVSITCHASQGISSNIGWLQQKPGKSFKGLIYHGTNLEDGVPSRFS 63 Query: 223 VLANG---DLLISEIKWEDMGNYKCI 245 +G L IS ++ ED +Y C+ Sbjct: 64 GSGSGADYSLTISSLESEDFADYYCV 89 >2IG2-H nrPDB Length = 455 Score = 34.1 bits (76), Expect = 0.067, Method: Composition-based stats. Identities = 24/192 (12%), Positives = 57/192 (29%), Gaps = 26/192 (13%) Query: 75 TIEIVCEMMG----SQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHV 130 T E+ C ++ W V + ++ + + ++ S V ++ Sbjct: 265 TPEVTCVVVDVSHEDPQVKFNWYVDGV---QVHNAKTKPREQQYNSTYRVVSVLTVLHQN 321 Query: 131 LSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSN 190 + + Y C + P T K ++P++ + ++ + Sbjct: 322 WLDGKEYKCKVSNKAL----------PAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQ 371 Query: 191 IQLPCRVHA-RP-RAEITWLNNENKE-------IVQGHRHRVLANGDLLISEIKWEDMGN 241 + L C V P + W +N E V L + + +W+ Sbjct: 372 VSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNV 431 Query: 242 YKCIARNVVGKD 253 + C + + Sbjct: 432 FSCSVMHEALHN 443 >5A2I-H nrPDB Length = 244 Score = 34.1 bits (76), Expect = 0.069, Method: Composition-based stats. Identities = 30/188 (15%), Positives = 52/188 (27%), Gaps = 25/188 (13%) Query: 82 MMGSQVPSIQWVVG-HLPRSELDDLDSNQVAEEAPSAIVRVRS---SHIIDHVLSEARTY 137 + S ++WV L + + V + +S + + + Y Sbjct: 37 VRQSPEKGLEWVAEIRLKSNNYATHYAESVKGRFTISRDDSKSSVYLQMNNLRAEDTGIY 96 Query: 138 TCVGRTG-SKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLM-GSNIQLPC 195 C G + +TV S + I+ T+++ L G + L C Sbjct: 97 YCTGVGQFAYWGQGTTVTVSASSGGGGSGGGGGSSGSSDIVVTQESALTTSPGETVTLTC 156 Query: 196 RVHA--------------RPRAEITWLNNENKEIVQGHRHRVLAN-----GDLLISEIKW 236 R +P T L G R + L I+ + Sbjct: 157 RSSTGAVTTSNYANWVQEKPDHLFTGLIGGTNNRAPGVPARFSGSLIGDKAALTITGAQT 216 Query: 237 EDMGNYKC 244 ED Y C Sbjct: 217 EDEAIYFC 224 >1A14-L nrPDB Length = 104 Score = 34.1 bits (76), Expect = 0.071, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 26/86 (30%), Gaps = 16/86 (18%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRHR 222 + T + +G + + CR + W V+ R Sbjct: 4 LTQTTSSLSASLGDRVTISCRASQDISNYLNWYQQNPDGTVKLLIYYTSNLHSEVPSRFS 63 Query: 223 VLANG---DLLISEIKWEDMGNYKCI 245 +G L IS ++ ED+ Y C Sbjct: 64 GSGSGTDYSLTISNLEQEDIATYFCQ 89 >1IGY-A nrPDB Length = 213 Score = 33.7 bits (75), Expect = 0.073, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 29/73 (39%), Gaps = 16/73 (21%) Query: 188 GSNIQLPCRVHARPRAEITWLN---NENKEIV---QGHRHRVLANG----------DLLI 231 G + L C+ ++W ++ +++ +R+ + + L I Sbjct: 15 GERVTLTCKASENVVTYVSWYQQKPEQSPKLLIYGASNRYTGVPDRFTGSGSATDFTLTI 74 Query: 232 SEIKWEDMGNYKC 244 S ++ ED+ +Y C Sbjct: 75 SSVQAEDLADYHC 87 >3UPA-A nrPDB Length = 107 Score = 33.7 bits (75), Expect = 0.073, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 32/101 (31%), Gaps = 20/101 (19%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLN--------------NENKEIVQGHR 220 ++ + + +G + + CR + + W ++ + V Sbjct: 3 QMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYDADDLQSGVPSRF 62 Query: 221 HRVLANGD--LLISEIKWEDMGNYKCIAR----NVVGKDTA 255 + D L IS ++ ED Y C N G+ T Sbjct: 63 SGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPNTFGQGTK 103 Score = 32.2 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 26/81 (32%), Gaps = 6/81 (7%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQW---VVGHLPRSELDDLDSNQVAEEAPSAIVRV 121 P+ L + G + I C S + W G P+ + D D Q + + Sbjct: 8 PSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYDADDLQSGVPSRFSGSGS 67 Query: 122 R---SSHIIDHVLSEARTYTC 139 + I + TY C Sbjct: 68 GTDFTLTISSLQPEDFATYYC 88 >5EU6-D nrPDB Length = 204 Score = 33.7 bits (75), Expect = 0.074, Method: Composition-based stats. Identities = 15/104 (14%), Positives = 28/104 (26%), Gaps = 18/104 (17%) Query: 173 KPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKE------IVQGHRHRVLAN 226 K + G N+ L C + W + + ++Q + + Sbjct: 2 KQEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSG 61 Query: 227 ------------GDLLISEIKWEDMGNYKCIARNVVGKDTADTF 258 L I+ + D Y C + G + TF Sbjct: 62 RLNASLDKSSGRSTLYIAASQPGDSATYLCAVLSSGGSNYKLTF 105 >1FNS-L nrPDB Length = 214 Score = 33.7 bits (75), Expect = 0.077, Method: Composition-based stats. Identities = 25/205 (12%), Positives = 51/205 (24%), Gaps = 33/205 (16%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVR-- 122 P+ L + G + I C + W P + L + + Sbjct: 8 PSSLSASLGDRVTISCSASQDINKYLNW-YQQKPDGAVKLLIFYTSSLHSGVPSRFSGSG 66 Query: 123 -----SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRII 177 S I + + TY C P T + P + Sbjct: 67 SGTDYSLTISNLEPEDIATYYC----------QQYEKLPWTFGGGTKLEVKRADAAPTVS 116 Query: 178 YTEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEI-----------VQGHRHRVL 224 + L + C ++ +I W + ++ + + + Sbjct: 117 IFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMS 176 Query: 225 ANGDLLISEIKWEDMGNYKCIARNV 249 + L E + + Y C A + Sbjct: 177 STLTLTKDEYERHNS--YTCEATHK 199 Score = 32.6 bits (72), Expect = 0.19, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 27/87 (31%), Gaps = 16/87 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ + + +G + + C + W + V+ R Sbjct: 3 QMTQSPSSLSASLGDRVTISCSASQDINKYLNWYQQKPDGAVKLLIFYTSSLHSGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCI 245 +G L IS ++ ED+ Y C Sbjct: 63 SGSGSGTDYSLTISNLEPEDIATYYCQ 89 >2ZNW-A nrPDB Length = 242 Score = 33.7 bits (75), Expect = 0.079, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 30/90 (33%), Gaps = 16/90 (17%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNN---ENKEIVQG----------HRHR 222 + + T G+++ L CR + W E+ ++ R Sbjct: 4 LTQSPATLSVTPGNSVSLSCRASQSIGNNLHWYQQKSHESPRLLIKYASQSISGIPSRFS 63 Query: 223 VLANGD---LLISEIKWEDMGNYKCIARNV 249 +G L I+ ++ ED G Y C N Sbjct: 64 GSGSGTDFTLSINSVETEDFGMYFCQQSNS 93 Score = 33.0 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 22/210 (10%), Positives = 46/210 (21%), Gaps = 30/210 (14%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQW---VVGHLPRS--ELDDLDSNQVAEEAPSAIV 119 P L G ++ + C S ++ W PR + + + + Sbjct: 8 PATLSVTPGNSVSLSCRASQSIGNNLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGS 67 Query: 120 RVR-SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178 + I + Y C + + G + Sbjct: 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEITGGGGSGGGGSGGGGSDIQLQ 127 Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAE--ITWLNNENKEIVQGHRHRVLANGD-------- 228 L + L C V +W+ ++ + + Sbjct: 128 ESGPSLVKPSQTLSLTCSVTGDSITSDYWSWIRKFPGNRLEYMGYVSYSGSTYYNPSLKS 187 Query: 229 --------------LLISEIKWEDMGNYKC 244 L ++ + ED Y C Sbjct: 188 RISITRDTSKNQYYLDLNSVTTEDTATYYC 217 >4FRW-A nrPDB Length = 218 Score = 33.7 bits (75), Expect = 0.082, Method: Composition-based stats. Identities = 31/187 (16%), Positives = 52/187 (27%), Gaps = 38/187 (20%) Query: 68 LQQADGATIEIVCEMMGS---QVPSIQWVVGHLPRS--ELDDLDSNQVAEEAPSAIVRV- 121 + G ++ C G QV + W EL L S +P+ RV Sbjct: 9 VTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVE 68 Query: 122 ----------RSSHIIDHVLSEARTYTCVGRTGSKTIYAST----VVHPPRSSRLTPEKT 167 S + + V ++ Y C T + + V+ PP S Sbjct: 69 QPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLN----P 124 Query: 168 YPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG 227 P ++ G + C P +TW + + R + Sbjct: 125 GPALEEG------------QGLTLAASCTAEGSPAPSVTW--DTEVKGTTSSRSFKHSRS 170 Query: 228 DLLISEI 234 + SE Sbjct: 171 AAVTSEF 177 Score = 29.9 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 14/29 (48%) Query: 64 PPTKLQQADGATIEIVCEMMGSQVPSIQW 92 P L++ G T+ C GS PS+ W Sbjct: 124 PGPALEEGQGLTLAASCTAEGSPAPSVTW 152 Score = 29.9 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 27/92 (29%), Gaps = 26/92 (28%) Query: 183 HLDLMGSNIQLPCRV---HARPRAEITWLNNENKE---------------IVQGHRHRVL 224 ++G + +LPC ++ W + E + + RV Sbjct: 9 VTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVE 68 Query: 225 A--------NGDLLISEIKWEDMGNYKCIARN 248 +G +L+ D G Y+C Sbjct: 69 QPPPPRNPLDGSVLLRNAVQADEGEYECRVST 100 >1Z7Z-I nrPDB Length = 450 Score = 33.4 bits (74), Expect = 0.10, Method: Composition-based stats. Identities = 28/196 (14%), Positives = 56/196 (28%), Gaps = 43/196 (21%) Query: 66 TKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSH 125 TK + ++G + + CE PR+++ P+ + R+ Sbjct: 291 TKPEVSEGTEVTVKCEAH--------------PRAKVT-------LNGVPAQPLGPRAQL 329 Query: 126 IIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYT--EKTH 183 ++ + S + A+ V + + PR+ Sbjct: 330 LLKATPEDNGR--------SFSCSATLEVAGQLIHKNQ-TRELRVLYGPRLDERDCPGNW 380 Query: 184 LDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYK 243 S C+ P E+ L + + G + + G Y Sbjct: 381 TWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGES-----------VTVTRDLEGTYL 429 Query: 244 CIARNVVGKDTADTFV 259 C AR+ G+ T + V Sbjct: 430 CRARSTQGEVTREVTV 445 >3O4O-B nrPDB Length = 339 Score = 33.4 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 30/117 (25%), Gaps = 7/117 (5%) Query: 131 LSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSN 190 L++ YTC+ R + I + + Sbjct: 89 LNDTGNYTCMLRNTTY-CSKVAFPLEVVQKDSCFNSPMKLPVHKLYIEYGIQRITCPNVD 147 Query: 191 IQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIAR 247 P V ITW K +Q + + +L + GNY C+ Sbjct: 148 GYFPSSVK----PTITWYMGCYK--IQNFNNVIPEGMNLSFLIALISNNGNYTCVVT 198 >5BRZ-D nrPDB Length = 197 Score = 33.4 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 28/88 (31%), Gaps = 8/88 (9%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRV--- 121 P L +G + + C S + ++QW + L E S + Sbjct: 8 PAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLYVRPYQREQTSGRLNASLD 67 Query: 122 -----RSSHIIDHVLSEARTYTCVGRTG 144 + +I ++ TY C R G Sbjct: 68 KSSGRSTLYIAASQPGDSATYLCAVRPG 95 >3WO4-B nrPDB Length = 312 Score = 33.4 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 23/144 (15%), Positives = 44/144 (30%), Gaps = 16/144 (11%) Query: 128 DHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLM 187 + + Y+CV + + P P++ + + Sbjct: 157 NAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNH----VAVEL 212 Query: 188 GSNIQLPCRVHARPRAEITWL----NNENKEIVQGHRHRVL-------ANGDLLISEIKW 236 G N++L C I W+ N + I + R++ A+ L I I Sbjct: 213 GKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGE 272 Query: 237 EDMGN-YKCIARNVVGKDTADTFV 259 ++ Y C + G DT + Sbjct: 273 SNLNVLYNCTVASTGGTDTKSFIL 296 >1CIC-A nrPDB Length = 214 Score = 33.4 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 29/74 (39%), Gaps = 16/74 (21%) Query: 188 GSNIQLPCRVHARPRAEITWLN---NENKEIV---QGHRHRVL--------ANGD--LLI 231 G + + C+ R + W ++ +++ RH + + D L I Sbjct: 16 GDRVSITCKASQDVRIAVAWYQQKPGQSPKLLIYWASTRHTGVPDRFTGSGSGTDFTLTI 75 Query: 232 SEIKWEDMGNYKCI 245 S ++ ED+ +Y C Sbjct: 76 SNVQSEDLADYFCQ 89 >4PD4-K nrPDB Length = 107 Score = 33.4 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 27/86 (31%), Gaps = 16/86 (18%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRHR 222 + T + +G + + CR + W + ++ R Sbjct: 4 LTQTPVSLAASLGDRVTISCRASQDINNFLNWYQQKPDGTIKLLIYYTSRLHAGVPSRFS 63 Query: 223 VLANG---DLLISEIKWEDMGNYKCI 245 +G L IS ++ ED+ Y C Sbjct: 64 GSGSGTDYSLTISNLEPEDIATYFCQ 89 >3NVQ-A nrPDB Length = 590 Score = 33.0 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 24/55 (43%), Gaps = 2/55 (3%) Query: 193 LPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIAR 247 L C + +R A +W + EN E H N L I + + G+Y C A+ Sbjct: 520 LSCPMESR-HATYSWRHKENVEQSCEPGH-QSPNCILFIENLTAQQYGHYFCEAQ 572 >1HEZ-A nrPDB Length = 214 Score = 33.0 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 30/201 (14%), Positives = 56/201 (27%), Gaps = 29/201 (14%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQW---VVGHLPRSELDDLDSNQVAEEAPSAIVRV 121 P+ L + G + I C S + W G P+ + S Q + + Sbjct: 8 PSSLSASVGDRVTITCRTSQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGS 67 Query: 122 R---SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178 + I + TY C S + + + T P + Sbjct: 68 GTDFTLTISSLQPEDFATYYC---QQSYSTPRTFGQGTKVEIKRTVAA-------PSVFI 117 Query: 179 TEKTHLDLMGSNIQLPCRVHA-RP-RAEITWLNNENKEIVQGHRHRVLA----------N 226 + L + C ++ P A++ W +N + V + Sbjct: 118 FPPSDEQLKSGTASVVCLLNNFYPREAKVQW-KVDNALQSGNSQESVTEQDSKDSTYSLS 176 Query: 227 GDLLISEIKWEDMGNYKCIAR 247 L +S+ +E Y C Sbjct: 177 STLTLSKADYEKHKVYACEVT 197 Score = 31.8 bits (70), Expect = 0.29, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 28/87 (32%), Gaps = 16/87 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ + + +G + + CR + + W + + + R Sbjct: 3 QMTQSPSSLSASVGDRVTITCRTSQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCI 245 +G L IS ++ ED Y C Sbjct: 63 SGSGSGTDFTLTISSLQPEDFATYYCQ 89 >4XMP-L nrPDB Length = 211 Score = 33.0 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 36/118 (30%), Gaps = 27/118 (22%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAE-ITWLNNENKE----IVQGHRHRVLANGD-- 228 + + +G + L C+ + W + + ++ G R D Sbjct: 4 VTQSPAILSVSLGERVTLSCKTSQAITPRHLVWHRQKGGQAPSLVMTGTSERASGIPDRF 63 Query: 229 ----------LLISEIKWEDMGNYKCIARNVVGKDTA----------DTFVYPVLNEE 266 L I+ ++ ED Y C G+ T F++P +E+ Sbjct: 64 IGSGSGTDFTLTITRLEAEDFAVYYCQCLEAFGQGTKLEIKRTVAAPSVFIFPPSDEQ 121 >2RCJ-C nrPDB Length = 523 Score = 33.0 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 24/192 (12%), Positives = 57/192 (29%), Gaps = 26/192 (13%) Query: 75 TIEIVCEMMG----SQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHV 130 T E+ C ++ W V + ++ + + ++ S V ++ Sbjct: 336 TPEVTCVVVDVSHEDPQVKFNWYVDGV---QVHNAKTKPREQQYNSTYRVVSVLTVLHQN 392 Query: 131 LSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSN 190 + + Y C + P T K ++P++ + ++ + Sbjct: 393 WLDGKEYKCKVSNKAL----------PAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQ 442 Query: 191 IQLPCRVHA-RP-RAEITWLNNENKE-------IVQGHRHRVLANGDLLISEIKWEDMGN 241 + L C V P + W +N E V L + + +W+ Sbjct: 443 VSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNV 502 Query: 242 YKCIARNVVGKD 253 + C + + Sbjct: 503 FSCSVMHEALHN 514 Score = 28.3 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 11/90 (12%), Positives = 26/90 (28%), Gaps = 16/90 (17%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLN----------------NENKEIVQGH 219 ++ + G + + C + + W + + Sbjct: 3 VLTQPPSASGTPGQRVTISCTGTSSGSITVNWYQQLPGMAPKLLIYRDAMRPSGVPTRFS 62 Query: 220 RHRVLANGDLLISEIKWEDMGNYKCIARNV 249 + + L IS ++ ED +Y C + N Sbjct: 63 GSKSGTSASLAISGLEAEDESDYYCASWNS 92 >2X1X-R nrPDB Length = 213 Score = 33.0 bits (73), Expect = 0.14, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 34/98 (34%), Gaps = 13/98 (13%) Query: 175 RIIYTEKTHLDLM-GSNIQLPC--RVHARPRAEITWL----NNENKEIVQGHRHRVLAN- 226 ++ + ++L G + L C R + W +++K++V + Sbjct: 106 DVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSE 165 Query: 227 -----GDLLISEIKWEDMGNYKCIARNVVGKDTADTFV 259 L I + D G Y C A + + TFV Sbjct: 166 MKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFV 203 >4XNY-L nrPDB Length = 211 Score = 32.6 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 40/118 (33%), Gaps = 27/118 (22%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVH-ARPRAEITWLNNENKE----IVQGHRHRVLA----- 225 + + T G L CR A ++ + W + ++ + ++ G R Sbjct: 4 LTQSPGTLSVSPGERATLSCRPSQAISKSHLAWYSQKSGQPPRLLLTGTYERASGVPDRF 63 Query: 226 -------NGDLLISEIKWEDMGNYKCIARNVVGKDTA----------DTFVYPVLNEE 266 N L I+ ++ ED Y C G+ T F++P +E+ Sbjct: 64 VGSGSGTNYTLTIASVEAEDFAVYFCQCFEGFGQGTKLEIKRTVAAPSVFIFPPSDEQ 121 >2ADF-H nrPDB Length = 218 Score = 32.6 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 27/184 (14%), Positives = 50/184 (27%), Gaps = 38/184 (20%) Query: 73 GATIEIVCEMMG-----------SQVPS-----IQWVVGHLPRSELDDLDSNQVAEEAPS 116 G T++I C+ G Q P + W + + + + A + Sbjct: 15 GETVKISCKASGYTFINYGMNWVKQAPGKGLKWMGWKNTNTGETTYGEEFRGRFAFSLET 74 Query: 117 AIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRI 176 ++ I + + TY C + T + P + Sbjct: 75 SV-STAYLQINNLKNEDTATYFCARDNPYYALDY-------WGQGTTVTVSSAKTTAPSV 126 Query: 177 IYTEKTHLDLMGSNIQLPCRVHAR-PRA-EITWLNNENKEIVQGHRHRVLANGDLLISEI 234 D GS++ L C V P +TW + L++G + Sbjct: 127 YPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSG------------SLSSGVHTFPAV 174 Query: 235 KWED 238 D Sbjct: 175 LQSD 178 Score = 31.8 bits (70), Expect = 0.30, Method: Composition-based stats. Identities = 14/97 (14%), Positives = 27/97 (27%), Gaps = 25/97 (25%) Query: 177 IYTEKTHLDLMGSNIQLPCRVHAR-------------PRAEITWLNNENKEIVQG----- 218 + L G +++ C+ P + W+ +N + Sbjct: 4 LVQSGPELKKPGETVKISCKASGYTFINYGMNWVKQAPGKGLKWMGWKNTNTGETTYGEE 63 Query: 219 -------HRHRVLANGDLLISEIKWEDMGNYKCIARN 248 ++ L I+ +K ED Y C N Sbjct: 64 FRGRFAFSLETSVSTAYLQINNLKNEDTATYFCARDN 100 >5CEF-A nrPDB Length = 375 Score = 32.6 bits (72), Expect = 0.17, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 4/75 (5%) Query: 58 LKFTKTPPTKLQQADGATIEIVCEMM--GSQ-VPSIQWVVGHLPRSELDDLDSNQVAEEA 114 +KF ++PP + + + A E C+ G P+ VV P LD N + A Sbjct: 263 VKFARSPPPSVAEVENAFREYTCDAQHLGVPSAPAQAIVVHDAPDRPQPRLDKN-LHNGA 321 Query: 115 PSAIVRVRSSHIIDH 129 ++ R+R + D Sbjct: 322 CVSVGRIRECPVFDI 336 >3MOQ-A nrPDB Length = 126 Score = 32.6 bits (72), Expect = 0.20, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 32/81 (39%), Gaps = 12/81 (14%) Query: 178 YTEKTHLDLMGSNIQLPC--RVHARPRAEITWLNNE-----NKEIVQGHRHRVLANG--- 227 T +T G ++ + C R + + W + + I G R+ N Sbjct: 5 QTPRTATKETGESLTINCVLRDASFELKDTGWYRTKLGSTNEQSISIGGRYVETVNKGSK 64 Query: 228 --DLLISEIKWEDMGNYKCIA 246 L IS+++ ED G YKC A Sbjct: 65 SFSLRISDLRVEDSGTYKCQA 85 >1AHW-A nrPDB Length = 214 Score = 32.6 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 12/86 (13%), Positives = 28/86 (32%), Gaps = 16/86 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQG-------------HRH 221 ++ + + +G + + C+ R + W + + + R Sbjct: 3 KMTQSPSSMYASLGERVTITCKASQDIRKYLNWYQQKPWKSPKTLIYYATSLADGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKC 244 +G L IS ++ +D Y C Sbjct: 63 SGSGSGQDYSLTISSLESDDTATYYC 88 >2PTT-A nrPDB Length = 110 Score = 32.6 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 16/78 (20%) Query: 181 KTHLDLMGSNIQLPCRVHA-RPRAEITWLNNENKEIVQ---------------GHRHRVL 224 GSN+ L P ITWL+ +N++I++ G + Sbjct: 11 PDINAYTGSNVTLKIHKDPLGPYRRITWLHTKNQKILEYNYNSTKTIFESEFKGRVYLEE 70 Query: 225 ANGDLLISEIKWEDMGNY 242 NG L IS ++ ED G Y Sbjct: 71 NNGALHISNVRKEDKGTY 88 >1EMT-L nrPDB Length = 214 Score = 32.2 bits (71), Expect = 0.23, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 26/87 (29%), Gaps = 16/87 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ T + +G + C + W + ++ R Sbjct: 3 QMTQTTSSLSASLGDRVTFSCSASQDISNYLNWYQQKPDGTIKLLIYYTSSLRSGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCI 245 +G L I+ ++ ED+ Y C Sbjct: 63 SGSGSGTDYSLTINNLEPEDIATYFCQ 89 >1JFQ-H nrPDB Length = 222 Score = 32.2 bits (71), Expect = 0.24, Method: Composition-based stats. Identities = 21/184 (11%), Positives = 50/184 (27%), Gaps = 35/184 (19%) Query: 73 GATIEIVCEMMG-------------SQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIV 119 G+++++ C+ G ++W+ + P + + + + Sbjct: 15 GSSVKMSCKASGYTFTSNGINWVKQRPGQGLEWIGYNNPGNGYITYNEK-FKGKTTLTVD 73 Query: 120 RVRSS---HIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRI 176 + ++ + ++ Y C R+ T + G P + Sbjct: 74 KSSNTAYMQLRSLTSEDSAVYFC-ARSEYYGGSYKFDYWG---QGTTLTVSSAGTTPPSV 129 Query: 177 IYTEKTHLDLMGSNIQLPCRVHAR-PRA-EITWLNNENKEIVQGHRHRVLANGDLLISEI 234 S + L C V P +TW + L++G + Sbjct: 130 YPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSG------------SLSSGVHTFPAV 177 Query: 235 KWED 238 D Sbjct: 178 LQSD 181 >4XNZ-L nrPDB Length = 209 Score = 32.2 bits (71), Expect = 0.25, Method: Composition-based stats. Identities = 16/116 (13%), Positives = 33/116 (28%), Gaps = 25/116 (21%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVH--ARPRAEITWLNNENKEIV---QGHRHRVLANG--- 227 + + T G L C+ + + ++ R + + Sbjct: 4 LTQSPGTLSVSPGERATLFCKASQGGNSLSWYQKRRGQPPRLLIYDTSRRASGIPDRFVG 63 Query: 228 -------DLLISEIKWEDMGNYKCIARNVVGKDTA----------DTFVYPVLNEE 266 L I+++ +D Y C G TA F++P +E+ Sbjct: 64 SGSGTDFSLTITKVDRDDFALYFCQQFEFFGLGTALEINRTVAAPSVFIFPPSDEQ 119 >1DR9-A nrPDB Length = 201 Score = 32.2 bits (71), Expect = 0.25, Method: Composition-based stats. Identities = 17/113 (15%), Positives = 30/113 (26%), Gaps = 11/113 (9%) Query: 118 IVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRII 177 I S I+ S+ TY CV K + + L+ + +P Sbjct: 61 ITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHL---AEVTLSVKADFPTPSISDFE 117 Query: 178 YTEKTHLDLMGSNIQLPCRVH-ARPRAEITWLNNENKEIVQGHRHRVLANGDL 229 ++ C P ++WL N + +L Sbjct: 118 IPTSNIRRII-------CSTSGGFPEPHLSWLENGEELNAINTTVSQDPETEL 163 >1PEW-A nrPDB Length = 109 Score = 32.2 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 31/93 (33%), Gaps = 21/93 (22%) Query: 179 TEKTHLDLMGSNIQLPC-RVHARPRAE-ITWLN----------NENKEI------VQGHR 220 + + G + + C R + + W +N+ G Sbjct: 6 QPHSVSESPGKTVTISCTRSSGNIASNYVQWYQQRSAPITVIYEDNQRPSGVPDRFAGSI 65 Query: 221 HRVLANGDLLISEIKWEDMGNYKCI---ARNVV 250 R + L IS +K ED +Y C ARNVV Sbjct: 66 DRSSNSASLTISGLKTEDEADYYCQSYDARNVV 98 >4WW2-A nrPDB Length = 207 Score = 32.2 bits (71), Expect = 0.27, Method: Composition-based stats. Identities = 13/94 (13%), Positives = 24/94 (25%), Gaps = 18/94 (19%) Query: 173 KPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKE------IVQGHRHRVLAN 226 K + G N+ L C + W + + ++Q + + Sbjct: 2 KQEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSG 61 Query: 227 ------------GDLLISEIKWEDMGNYKCIARN 248 L I+ + D Y C N Sbjct: 62 RLNASLDKSSGRSTLYIAASQPGDSATYLCAGVN 95 >5B22-A nrPDB Length = 211 Score = 31.8 bits (70), Expect = 0.29, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 37/117 (31%), Gaps = 27/117 (23%) Query: 174 PRIIYTEKTHLDLMGSNIQLPCRVHARPR-AEITWLNNENKEI-------------VQGH 219 P II + G N+ L C + +I+W K VQG Sbjct: 1 PSIIVEPH-VTAVWGKNVSLKCLIEVNETITQISWEKIHGKSTQTVAVHHPQYGFSVQGD 59 Query: 220 -------RHRVLANGDLLISEIKWEDMGNYKCIAR-----NVVGKDTADTFVYPVLN 264 ++ L + + + I + D G Y C A N T V P ++ Sbjct: 60 YQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVS 116 Score = 29.9 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 21/154 (13%), Positives = 45/154 (29%), Gaps = 31/154 (20%) Query: 73 GATIEIVCEM-MGSQVPSIQWVV----------GHLPRSELDDLDSNQVAEEAPSAIVRV 121 G + + C + + + I W H P+ Q + + Sbjct: 14 GKNVSLKCLIEVNETITQISWEKIHGKSTQTVAVHHPQYGFSVQGDYQGRVLFKNYSLND 73 Query: 122 RSSHIIDHVLSEARTYTCVGRT----GSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRII 177 + + + S++ Y C T +++ TV+ P S + Sbjct: 74 ATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKG------------- 120 Query: 178 YTEKTHLDLMGSNIQLPC-RVHARPRAEITWLNN 210 + +D + C +P A+I W + Sbjct: 121 --PDSLIDGGNETVAAVCVAATGKPVAQIDWEGD 152 >4L1H-A nrPDB Length = 107 Score = 31.4 bits (69), Expect = 0.38, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 27/87 (31%), Gaps = 16/87 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ + + +G + + CR + W + + + R Sbjct: 3 QMTQSPSSLSASVGDRVTITCRASQDIIKYLAWYQQKPGKAPKLLIYEASNLQAGVPSRF 62 Query: 222 RVLANGD---LLISEIKWEDMGNYKCI 245 +G L IS ++ ED Y C Sbjct: 63 SGSGSGTDFTLTISSLQPEDFATYYCQ 89 Score = 29.5 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 26/81 (32%), Gaps = 6/81 (7%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQW---VVGHLPRSELDDLDSNQVAEEAPSAIVRV 121 P+ L + G + I C + + W G P+ + + + Q + + Sbjct: 8 PSSLSASVGDRVTITCRASQDIIKYLAWYQQKPGKAPKLLIYEASNLQAGVPSRFSGSGS 67 Query: 122 R---SSHIIDHVLSEARTYTC 139 + I + TY C Sbjct: 68 GTDFTLTISSLQPEDFATYYC 88 >3U0W-L nrPDB Length = 214 Score = 31.4 bits (69), Expect = 0.39, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 27/87 (31%), Gaps = 16/87 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQ-------------GHRH 221 ++ T + +G + + C + W + V+ R Sbjct: 3 QMTQTTSSLSASLGDRVTISCSASQGISNYLNWFQQKPDGTVKLLIYYTSSLHSGVPSRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKCI 245 +G L IS ++ ED+ Y C Sbjct: 63 SGSGSGTDYSLTISNLEPEDIATYYCQ 89 >1QGC-4 nrPDB Length = 218 Score = 31.4 bits (69), Expect = 0.40, Method: Composition-based stats. Identities = 14/95 (14%), Positives = 28/95 (29%), Gaps = 20/95 (21%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAE----ITWL--NNENKEIVQGHRHRVLANGD- 228 + + + +G + CR + + W + +R L +G Sbjct: 4 LTQSPASLAVSLGQRATISCRASESVDSSGHSFMHWYQQKPGQPPKLLIYRASNLESGIP 63 Query: 229 -------------LLISEIKWEDMGNYKCIARNVV 250 L I ++ +D+ Y C N V Sbjct: 64 DRFSGSGSRTDFTLTIDPVEADDVATYYCQQSNEV 98 >1ZVO-C nrPDB Length = 512 Score = 31.0 bits (68), Expect = 0.47, Method: Composition-based stats. Identities = 15/102 (14%), Positives = 29/102 (28%), Gaps = 7/102 (6%) Query: 167 TYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEIT--WLNNENKEIVQ-----GH 219 + P S + L C + +T W + + Sbjct: 129 SAPTKAPDVFPIISGCRHPKDNSPVVLACLITGYHPTSVTVTWYMGTQSQPQRTFPEIQR 188 Query: 220 RHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYP 261 R L + ++ G YKC+ ++ K + F +P Sbjct: 189 RDSYYMTSSQLSTPLQQWRQGEYKCVVQHTASKSKKEIFRWP 230 >3QS9-E nrPDB Length = 527 Score = 31.0 bits (68), Expect = 0.51, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 10/38 (26%) Query: 178 YTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEI 215 K + S Q C P TW +K Sbjct: 412 IRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSP 449 >5XCQ-A nrPDB Length = 169 Score = 31.0 bits (68), Expect = 0.55, Method: Composition-based stats. Identities = 12/93 (12%), Positives = 27/93 (29%), Gaps = 25/93 (26%) Query: 177 IYTEKTHLDLMGSNIQLPCRVHAR-------------PRAEITWL-----NNENKEIVQG 218 + + G +++ C+ P + W+ + + + Sbjct: 6 LVQSGPEVQKPGETVRISCKASGYTFTTAGMQWVQKMPGKSLKWIGWINTRSGVPKYAED 65 Query: 219 HRHR-------VLANGDLLISEIKWEDMGNYKC 244 + R + L I+ +K ED Y C Sbjct: 66 FKGRFAFSLETSASIAYLHINNLKNEDTATYFC 98 >5XP1-A nrPDB Length = 109 Score = 31.0 bits (68), Expect = 0.59, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 28/81 (34%), Gaps = 6/81 (7%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVV---GHLPRSELDDLDSNQVAEEAPSAIVRV 121 P+ L + G + I C+ + + W G P+ + + + Q + + Sbjct: 9 PSSLSASVGDRVTITCQASQDIIKYLNWYQQTPGKAPKLLIYEASNLQAGVPSRFSGSGS 68 Query: 122 RSSH---IIDHVLSEARTYTC 139 + + I + TY C Sbjct: 69 GTDYTFTISSLQPEDIATYYC 89 >1KNO-A nrPDB Length = 214 Score = 30.7 bits (67), Expect = 0.67, Method: Composition-based stats. Identities = 27/204 (13%), Positives = 55/204 (26%), Gaps = 31/204 (15%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVV----GHLPRSEL--DDLDSNQVAEEAPSAI 118 P+ L + G + + C + W+ G + R LDS + S Sbjct: 8 PSSLSASLGERVSLTCRASQEISGYLSWLQQKPDGTIKRLIYAASTLDSGVPKRFSGSRS 67 Query: 119 VRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178 S I + Y C+ T + L + P + Sbjct: 68 GSDYSLTISSLESEDFADYYCL----QYASSPYTFGGGTKLEILRADAA------PTVSI 117 Query: 179 TEKTHLDLMGSNIQLPCRVHARPRAEI--TWLNNENKEI-----------VQGHRHRVLA 225 + L + C ++ +I W + ++ + + + + Sbjct: 118 FPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSS 177 Query: 226 NGDLLISEIKWEDMGNYKCIARNV 249 L E + + Y C A + Sbjct: 178 TLTLTKDEYERHNS--YTCEATHK 199 Score = 29.9 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 30/86 (34%), Gaps = 16/86 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQG-------------HRH 221 ++ + + +G + L CR ++WL + ++ R Sbjct: 3 QMTQSPSSLSASLGERVSLTCRASQEISGYLSWLQQKPDGTIKRLIYAASTLDSGVPKRF 62 Query: 222 RVLANG---DLLISEIKWEDMGNYKC 244 +G L IS ++ ED +Y C Sbjct: 63 SGSRSGSDYSLTISSLESEDFADYYC 88 >5K8D-B nrPDB Length = 865 Score = 30.7 bits (67), Expect = 0.71, Method: Composition-based stats. Identities = 27/192 (14%), Positives = 56/192 (29%), Gaps = 26/192 (13%) Query: 75 TIEIVCEMMG----SQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHV 130 T E+ C ++ W V + E+ + + E+ S V ++ Sbjct: 675 TPEVTCVVVDVSHEDPEVKFNWYVDGV---EVHNAKTKPREEQYNSTYRVVSVLTVLHQD 731 Query: 131 LSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSN 190 + Y C + P T K ++P++ + +L + Sbjct: 732 WLNGKEYKCKVSNKAL----------PAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQ 781 Query: 191 IQLPCRVHA-RP-RAEITWLNNENKE-------IVQGHRHRVLANGDLLISEIKWEDMGN 241 + L C V P + W +N E V L + + +W+ Sbjct: 782 VSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNV 841 Query: 242 YKCIARNVVGKD 253 + C + + Sbjct: 842 FSCSVMHEALHN 853 >7FAB-L nrPDB Length = 208 Score = 30.7 bits (67), Expect = 0.74, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 28/83 (33%), Gaps = 12/83 (14%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAE---ITWLN---NENKEIV---QGHRHRVLAN 226 ++ + G + + C + + W +++ R V + Sbjct: 3 VLTQPPSVSGAPGQRVTISCTGSSSNIGAGHNVKWYQQLPGTAPKLLIFHNNARFSVSKS 62 Query: 227 GD---LLISEIKWEDMGNYKCIA 246 G L I+ ++ ED +Y C + Sbjct: 63 GTSATLAITGLQAEDEADYYCQS 85 >2BNR-D nrPDB Length = 203 Score = 30.7 bits (67), Expect = 0.76, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 38/127 (29%), Gaps = 15/127 (11%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELD---DLDSNQVAEEAPSAIVRV 121 P L +G + + C S + ++QW + S + Sbjct: 7 PAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNASLD 66 Query: 122 RS-----SHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPR- 175 +S +I ++ TY C R S Y P R T +P Q P Sbjct: 67 KSSGRSTLYIAASQPGDSATYLCAVRPTSGGSY------IPTFGRGTSLIVHPYIQNPDP 120 Query: 176 IIYTEKT 182 +Y + Sbjct: 121 AVYQLRD 127 Score = 29.9 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 13/96 (13%), Positives = 24/96 (25%), Gaps = 18/96 (18%) Query: 174 PRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKE------IVQGHRHRVLAN- 226 + G N+ L C + W + + ++Q + + Sbjct: 1 QEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGR 60 Query: 227 -----------GDLLISEIKWEDMGNYKCIARNVVG 251 L I+ + D Y C R G Sbjct: 61 LNASLDKSSGRSTLYIAASQPGDSATYLCAVRPTSG 96 >5F1N-B nrPDB Length = 125 Score = 30.3 bits (66), Expect = 0.86, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 19/65 (29%), Gaps = 7/65 (10%) Query: 168 YPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG 227 P+I + H G L C V EI ++++ + Sbjct: 26 DAVQHPPKIQVYSR-HPAENGKPNFLNCYVSGFHPPEI------EIDLLKNGKEMKAEQT 78 Query: 228 DLLIS 232 DL S Sbjct: 79 DLSFS 83 >4JJH-A nrPDB Length = 133 Score = 30.3 bits (66), Expect = 0.91, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 27/92 (29%), Gaps = 26/92 (28%) Query: 183 HLDLMGSNIQLPCRV---HARPRAEITWLNNENKE---------------IVQGHRHRVL 224 ++G + +LPC ++ W + E + + RV Sbjct: 14 VTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVE 73 Query: 225 A--------NGDLLISEIKWEDMGNYKCIARN 248 +G +L+ D G Y+C Sbjct: 74 QPPPPRNPLDGSVLLRNAVQADEGEYECRVST 105 >4GJT-B nrPDB Length = 123 Score = 30.3 bits (66), Expect = 0.91, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 27/92 (29%), Gaps = 26/92 (28%) Query: 183 HLDLMGSNIQLPCRV---HARPRAEITWLNNENKE---------------IVQGHRHRVL 224 ++G + +LPC ++ W + E + + RV Sbjct: 10 VTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVE 69 Query: 225 A--------NGDLLISEIKWEDMGNYKCIARN 248 +G +L+ D G Y+C Sbjct: 70 QPPPPRNPLDGSVLLRNAVQADEGEYECRVST 101 >1HZH-H nrPDB Length = 457 Score = 30.3 bits (66), Expect = 0.97, Method: Composition-based stats. Identities = 27/192 (14%), Positives = 56/192 (29%), Gaps = 26/192 (13%) Query: 75 TIEIVCEMMG----SQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHV 130 T E+ C ++ W V + E+ + + E+ S V ++ Sbjct: 266 TPEVTCVVVDVSHEDPEVKFNWYVDGV---EVHNAKTKPREEQYNSTYRVVSVLTVLHQD 322 Query: 131 LSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSN 190 + Y C + P T K ++P++ + +L + Sbjct: 323 WLNGKEYKCKVSNKAL----------PAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQ 372 Query: 191 IQLPCRVHA-RP-RAEITWLNNENKE-------IVQGHRHRVLANGDLLISEIKWEDMGN 241 + L C V P + W +N E V L + + +W+ Sbjct: 373 VSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNV 432 Query: 242 YKCIARNVVGKD 253 + C + + Sbjct: 433 FSCSVMHEALHN 444 >2Q20-A nrPDB Length = 109 Score = 29.9 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 27/81 (33%), Gaps = 6/81 (7%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRS-ELDDLDSNQVAEEAPSAIVRVRS 123 P+ L + G + I C+ + W ++ +L D++ + PS S Sbjct: 10 PSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGS 69 Query: 124 -----SHIIDHVLSEARTYTC 139 I + TY C Sbjct: 70 GTDFTFTISSLQPEDIATYYC 90 >4BFI-B nrPDB Length = 211 Score = 29.9 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 27/174 (15%), Positives = 51/174 (29%), Gaps = 31/174 (17%) Query: 75 TIEIVCEMMGSQVP-SIQW-VVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHII----- 127 T + C + SQ P + W + + P+ R+ + + Sbjct: 16 TASLRCSLKTSQEPLIVTWQKKKAVSPENMVTYSKTHGVVIQPAYKDRINVTELGLWNSS 75 Query: 128 ----DHVLSEARTYTCVGRT-GSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKT 182 + L + Y C+ T GS+ + + + + Y + Sbjct: 76 ITFWNTTLEDEGCYMCLFNTFGSQKVSGTACLTLYVQPIVHLHYNY-----------FED 124 Query: 183 HLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKW 236 HL++ C ARP I+W I +NG ++ I Sbjct: 125 HLNI-------TCSATARPAPAISW-KGTGTGIENSTESHFHSNGTTSVTSILR 170 Score = 29.5 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 30/85 (35%), Gaps = 11/85 (12%) Query: 191 IQLPCRVHARPRAEITWLNNENKEIVQGHRHRV------LANGDLLISEIKWEDMGNYKC 244 + + P +T+ I ++ R+ L N + ED G Y C Sbjct: 32 VTWQKKKAVSPENMVTYSKTHGVVIQPAYKDRINVTELGLWNSSITFWNTTLEDEGCYMC 91 Query: 245 I-----ARNVVGKDTADTFVYPVLN 264 + ++ V G +V P+++ Sbjct: 92 LFNTFGSQKVSGTACLTLYVQPIVH 116 >1B0W-A nrPDB Length = 108 Score = 29.9 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 27/81 (33%), Gaps = 6/81 (7%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRS-ELDDLDSNQVAEEAPSAIVRVRS 123 P+ L + G + I C+ + W L ++ L D++ + PS S Sbjct: 8 PSSLSASVGDRVTITCQASQDISDYLIWYQQKLGKAPNLLIYDASTLETGVPSRFSGSGS 67 Query: 124 -----SHIIDHVLSEARTYTC 139 I + TY C Sbjct: 68 GTEYTFTISSLQPEDIATYYC 88 >1QFW-L nrPDB Length = 114 Score = 29.9 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 12/94 (12%), Positives = 29/94 (30%), Gaps = 20/94 (21%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVH----ARPRAEITWL--NNENKEIVQGHRHRVLANGD- 228 + + + +G + CR + + + W + +R L +G Sbjct: 4 LTQSPDSLAVSLGQRATISCRASESVDSYGNSFMQWYQQKPGQPPKLLIYRASNLESGIP 63 Query: 229 -------------LLISEIKWEDMGNYKCIARNV 249 L I+ ++ +D+ Y C + Sbjct: 64 ARFSGTGSRTDFTLTINPVEADDVATYYCQQSDE 97 >4WWK-A nrPDB Length = 209 Score = 29.9 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 18/112 (16%), Positives = 32/112 (28%), Gaps = 7/112 (6%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSE----LDDLDSNQVAEEAPSAIVR 120 P L +GA + + C S W + + N+ + + + Sbjct: 9 PGPLSVPEGAIVSLNCTYSNSAFQYFMWYRQYSRKGPELLMYTYSSGNKEDGRFTAQVDK 68 Query: 121 VR---SSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYP 169 S I D S++ TY C T + + + P P Sbjct: 69 SSKYISLFIRDSQPSDSATYLCAMSGDLNTNAGKSTFGDGTTLTVKPNIQNP 120 >1SEQ-L nrPDB Length = 213 Score = 29.9 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 29/85 (34%), Gaps = 17/85 (20%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENK-----------EIVQG--HRHR 222 + + +GS++ L C + + + W ++ + G R Sbjct: 4 LTQSPAIMSASLGSSVTLTCSASSS-VSYMHWYQQKSGTSPVLLIYTTSNLASGVPSRFS 62 Query: 223 VLANG---DLLISEIKWEDMGNYKC 244 +G L IS ++ D +Y C Sbjct: 63 GSGSGTFYSLTISSVEASDAADYYC 87 >1N26-A nrPDB Length = 325 Score = 29.9 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 25/72 (34%), Gaps = 2/72 (2%) Query: 174 PRIIYTEKTHLDLMGSNIQLPCR-VHARPRAEITWLNNENKEIVQGHRHRVLANGDLLIS 232 P L G ++ L C V A + W+ + R + LL+ Sbjct: 7 PAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGR-RLLLR 65 Query: 233 EIKWEDMGNYKC 244 ++ D GNY C Sbjct: 66 SVQLHDSGNYSC 77 >2QHR-L nrPDB Length = 218 Score = 29.9 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 15/32 (46%), Gaps = 4/32 (12%) Query: 229 LLISEIKWEDMGNYKCIARNVVGKDTADTFVY 260 L IS I+ ED Y C VG + FVY Sbjct: 77 LSISNIQPEDEAIYIC----GVGDTIKEQFVY 104 >4E0R-B nrPDB Length = 101 Score = 29.5 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 10/72 (13%), Positives = 23/72 (31%), Gaps = 6/72 (8%) Query: 184 LDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLA-NGDLLISEIKWED---- 238 G+ L C +I+ ++ ++G ++ ++ N D + D Sbjct: 16 PASAGTKNVLNCFAAGFHPPKISITLMKDGVPMEGAQYSDMSFNDDWTFQRLVHADFTPS 75 Query: 239 -MGNYKCIARNV 249 Y C + Sbjct: 76 SGSTYACKVEHE 87 >3O81-A nrPDB Length = 119 Score = 29.5 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 10/72 (13%), Positives = 23/72 (31%), Gaps = 6/72 (8%) Query: 184 LDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLA-NGDLLISEIKWED---- 238 G+ L C +I+ ++ ++G ++ ++ N D + D Sbjct: 34 PASAGTKNVLNCFAAGFHPPKISITLMKDGVPMEGAQYSDMSFNDDWTFQRLVHADFTPS 93 Query: 239 -MGNYKCIARNV 249 Y C + Sbjct: 94 SGSTYACKVEHE 105 >5V4N-C nrPDB Length = 216 Score = 29.5 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 28/82 (34%), Gaps = 8/82 (9%) Query: 173 KPRIIYTEKTHLDLMGSNIQLPCRVHA-RP-RAEITWLNNENKEIVQGHRHRVLANGD-- 228 +P++ L N+ L C V P E+ W N +E ++ NGD Sbjct: 122 EPKVTVYPSKTQPLQHHNL-LVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 180 Query: 229 ---LLISEIKWEDMGNYKCIAR 247 L++ E Y C Sbjct: 181 FQTLVMLETVPRSGEVYTCQVE 202 >4AH2-B nrPDB Length = 229 Score = 29.5 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 28/82 (34%), Gaps = 8/82 (9%) Query: 173 KPRIIYTEKTHLDLMGSNIQLPCRVHA-RP-RAEITWLNNENKEIVQGHRHRVLANGD-- 228 +P++ L N+ L C V P E+ W N +E ++ NGD Sbjct: 127 EPKVTVYPSKTQPLQHHNL-LVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 185 Query: 229 ---LLISEIKWEDMGNYKCIAR 247 L++ E Y C Sbjct: 186 FQTLVMLETVPRSGEVYTCQVE 207 >1KG0-B nrPDB Length = 188 Score = 29.5 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 28/82 (34%), Gaps = 8/82 (9%) Query: 173 KPRIIYTEKTHLDLMGSNIQLPCRVHA-RP-RAEITWLNNENKEIVQGHRHRVLANGD-- 228 +P++ L N+ L C V P E+ W N +E ++ NGD Sbjct: 94 EPKVTVYPSKTQPLQHHNL-LVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 152 Query: 229 ---LLISEIKWEDMGNYKCIAR 247 L++ E Y C Sbjct: 153 FQTLVMLETVPRSGEVYTCQVE 174 >5GJY-B nrPDB Length = 104 Score = 29.5 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 15/98 (15%), Positives = 31/98 (31%), Gaps = 7/98 (7%) Query: 170 GAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGD- 228 P++ + H G+ L C V +I +N E ++ ++ ++ GD Sbjct: 6 AKAAPKVQVYSR-HPATAGTENILNCYVEGFHPPKIDIALLKNGEPMKDVKYNDMSFGDD 64 Query: 229 -----LLISEIKWEDMGNYKCIARNVVGKDTADTFVYP 261 L+ + Y C + + P Sbjct: 65 WTFQRLVYAPFTPTKSDVYTCRVDHEAFTEPQSFRWEP 102 >4QNP-F nrPDB Length = 212 Score = 29.1 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 26/89 (29%), Gaps = 15/89 (16%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHAR--------------PRAEITWLNN-ENKEIVQGHR 220 + + G + + CR + P+ I +N + + Sbjct: 4 LSQSPAILSASPGEKVTMTCRTSSSVSYMHWYQQKPGSSPKPWIYATSNLASGVPFRFSG 63 Query: 221 HRVLANGDLLISEIKWEDMGNYKCIARNV 249 + L IS ++ ED Y C N Sbjct: 64 SGSGTSYSLTISRVEAEDAATYYCQQWNS 92 >2FD6-L nrPDB Length = 214 Score = 29.1 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 12/88 (13%), Positives = 25/88 (28%), Gaps = 15/88 (17%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHAR--------------PRAEITWL-NNENKEIVQGHR 220 + + +G + + C + P+ I + + + Sbjct: 4 LTQSPDITAASLGQKVTITCSASSSVSYMHWYQQKSGTSPKPWIFEISKLASGVPARFSG 63 Query: 221 HRVLANGDLLISEIKWEDMGNYKCIARN 248 + L IS ++ ED Y C N Sbjct: 64 SGSGTSYSLTISSMEAEDAAIYYCQQWN 91 >5C09-D nrPDB Length = 200 Score = 29.1 bits (63), Expect = 2.0, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 28/88 (31%), Gaps = 7/88 (7%) Query: 65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSE----LDDLDSNQVAEEAPSAIVR 120 P L +GA + + C S W + + N+ + + + Sbjct: 6 PGPLSVPEGAIVSLNCTYSNSAFQYFMWYRQYSRKGPELLMYTYSSGNKEDGRFTAQVDK 65 Query: 121 VR---SSHIIDHVLSEARTYTCVGRTGS 145 S I D S++ TY C R S Sbjct: 66 SSKYISLFIRDSQPSDSATYLCAMRGDS 93 >5IUE-B nrPDB Length = 182 Score = 29.1 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 31/88 (35%), Gaps = 7/88 (7%) Query: 168 YPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANG 227 P + P+I + H G + L C V ++I +N E ++ H L+ Sbjct: 68 DPIQRTPKIQVYSR-HPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFS 126 Query: 228 D------LLISEIKWEDMGNYKCIARNV 249 L +E + Y C +V Sbjct: 127 KDWSFYLLYYTEFTPTEKDEYACRVNHV 154 >5NQK-B nrPDB Length = 251 Score = 29.1 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 18/51 (35%), Gaps = 1/51 (1%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLAN 226 I + K G N+ L C + + W + + ++ + + N Sbjct: 3 ITQSPKYLFRKEGQNVTLSCEQNLNHD-AMYWYRQDPGQGLRLIYYSQIVN 52 >5DMK-B nrPDB Length = 212 Score = 28.7 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 35/202 (17%), Positives = 60/202 (29%), Gaps = 36/202 (17%) Query: 69 QQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIID 128 Q A T E+V GS+ + G + +R+ + +I + Sbjct: 11 QLAKELTAELVPRGSGSERHFVHQFKGECYFTNGTQR-------------IRLVTRYIYN 57 Query: 129 HVL-----SEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEK---TYPGAQKP---RII 177 S+ Y V G + + R+ Y + P R + Sbjct: 58 REEYLRFDSDVGEYRAVTELGRHSAEYYNKQYLERTRAELDTACRHNYEETEVPTSLRRL 117 Query: 178 YTEKTHLDLMGSNI-----QLPCRVHARPRAEI--TWLNNENKEIVQGHRHRVLANGD-- 228 + L + L C V A+I W N +E V +++ NGD Sbjct: 118 EQPNVAISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWT 177 Query: 229 ---LLISEIKWEDMGNYKCIAR 247 L++ E+ Y C Sbjct: 178 FQVLVMLEMTPHQGEVYTCHVE 199 >3O11-L nrPDB Length = 212 Score = 28.7 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 12/86 (13%), Positives = 24/86 (27%), Gaps = 17/86 (19%) Query: 176 IIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKE-----IVQGHR---------- 220 + + G + + C + + + W ++ I R Sbjct: 4 LTQSPAIMSASPGEKVTMTCSASSS-VSYMHWYQQKSGTSPKRWIYDSSRLASGVPSRFS 62 Query: 221 -HRVLANGDLLISEIKWEDMGNYKCI 245 + L IS ++ ED Y C Sbjct: 63 GGGSGTSYSLTISNMEAEDAATYFCQ 88 >4ONO-A nrPDB Length = 395 Score = 28.7 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 31/87 (35%), Gaps = 7/87 (8%) Query: 169 PGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGD 228 P + P+I + H G + L C V ++I +N E ++ H L+ Sbjct: 1 PIQRTPKIQVYSR-HPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSK 59 Query: 229 ------LLISEIKWEDMGNYKCIARNV 249 L +E + Y C +V Sbjct: 60 DWSFYLLYYTEFTPTEKDEYACRVNHV 86 >1LIL-A nrPDB Length = 212 Score = 28.3 bits (61), Expect = 3.7, Method: Composition-based stats. Identities = 10/85 (11%), Positives = 19/85 (22%), Gaps = 16/85 (18%) Query: 177 IYTEKTHLDLMGSNIQLPCRVHARPRAEITWL----------------NNENKEIVQGHR 220 + + G ++ C A + W + + Sbjct: 3 VTQPPSLSVSPGQTARITCSGEKLGDAYVCWYQQRPGQSPVVVIYQDNRRPSGIPERFSG 62 Query: 221 HRVLANGDLLISEIKWEDMGNYKCI 245 L IS + D +Y C Sbjct: 63 SSSGNTATLTISGTQTLDEADYYCQ 87 >5OWG-A nrPDB Length = 243 Score = 28.3 bits (61), Expect = 3.8, Method: Composition-based stats. Identities = 6/38 (15%), Positives = 13/38 (34%) Query: 207 WLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKC 244 W + + + + G + ++ ED N C Sbjct: 129 WFKPSKERELPEWAKAIFSGGMIAAGNVREEDELNKIC 166 >1IAI-M nrPDB Length = 215 Score = 27.2 bits (58), Expect = 7.2, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 27/92 (29%), Gaps = 17/92 (18%) Query: 175 RIIYTEKTHLDLMGSNIQLPC----------------RVHARPRAEITWLNN-ENKEIVQ 217 ++ + G + + C + P+ I +N + V+ Sbjct: 3 QLTQSPAFMAASPGEKVTITCSVSSSISSSNLHWYQQKSETSPKPWIYGTSNLASGVPVR 62 Query: 218 GHRHRVLANGDLLISEIKWEDMGNYKCIARNV 249 + L IS ++ ED Y C N Sbjct: 63 FSGSGSGTSYSLTISSMEAEDAATYYCQQWNS 94 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.113 0.303 Lambda K H 0.267 0.0353 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,958,771 Number of Sequences: 36641 Number of extensions: 316063 Number of successful extensions: 1541 Number of sequences better than 10.0: 160 Number of HSP's better than 10.0 without gapping: 75 Number of HSP's successfully gapped in prelim test: 129 Number of HSP's that attempted gapping in prelim test: 1081 Number of HSP's gapped (non-prelim): 375 length of query: 267 length of database: 10,336,785 effective HSP length: 95 effective length of query: 172 effective length of database: 6,855,890 effective search space: 1179213080 effective search space used: 1179213080 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 58 (27.2 bits)