BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q08603 (331 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3HXF-B nrPDB 685 0.0 1N4R-B nrPDB 141 3e-34 2ZIR-B nrPDB 138 3e-33 4YDO-B nrPDB 99 2e-21 4LNB-B nrPDB 95 5e-20 3DRA-B nrPDB 82 4e-16 3SFX-B nrPDB 75 5e-14 1UMP-A nrPDB 32 0.34 5JOZ-A nrPDB 30 1.7 1W6K-A nrPDB 29 3.2 2QFC-A nrPDB 28 7.1 >3HXF-B nrPDB Length = 331 Score = 685 bits (1768), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/331 (100%), Positives = 331/331 (100%) Query: 1 MGTQQKDVTIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLM 60 MGTQQKDVTIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLM Sbjct: 1 MGTQQKDVTIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLM 60 Query: 61 GQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVV 120 GQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVV Sbjct: 61 GQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVV 120 Query: 121 AYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGG 180 AYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGG Sbjct: 121 AYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGG 180 Query: 181 FGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVC 240 FGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVC Sbjct: 181 FGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVC 240 Query: 241 YSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSL 300 YSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSL Sbjct: 241 YSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSL 300 Query: 301 LGEEQIKPVSPVFCMPEEVLQRVNVQPELVS 331 LGEEQIKPVSPVFCMPEEVLQRVNVQPELVS Sbjct: 301 LGEEQIKPVSPVFCMPEEVLQRVNVQPELVS 331 >1N4R-B nrPDB Length = 377 Score = 141 bits (356), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 95/318 (29%), Positives = 154/318 (48%), Gaps = 34/318 (10%) Query: 38 EYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQ----------HECG---- 83 Y E R++ ++ L+ +D++ L +NK++I+ +I S Q CG Sbjct: 39 RYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGS 98 Query: 84 ---GVSASIGHDP---------HLLYTLSAVQ-ILTLYDSIHVINVDKVVAYVQSLQKED 130 G+ + +P H+ T + + ++ L D + ++ + +A +++LQ ED Sbjct: 99 SYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLED 158 Query: 131 GSFAGDIWG-EIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSES 189 GSF G E D RF +CA +L ++++KAI ++ M++D G G ES Sbjct: 159 GSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLES 218 Query: 190 HAGQIYCCTGFLAITSQLHQVNS----DLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWV 245 H G +C L + +L +V S + + W RQ G +GRP K D CYS+WV Sbjct: 219 HGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQ--QNGYHGRPNKPVDTCYSFWV 276 Query: 246 LASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQ 305 A+LK++ + + EK R++IL+ QD GGFA P D H FGI GLSL+ E Sbjct: 277 GATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESG 336 Query: 306 IKPVSPVFCMPEEVLQRV 323 I V P + +R+ Sbjct: 337 ICKVHPALNVSTRTSERL 354 >2ZIR-B nrPDB Length = 440 Score = 138 bits (348), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 100/339 (29%), Positives = 165/339 (48%), Gaps = 36/339 (10%) Query: 18 LLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQ-LHRMNKEEILVFIK 76 L EKH Y+ + D C+ + R YW L ++L+ + + ++ ++ F++ Sbjct: 76 LQREKHFHYLKRGLRQLTDAYECL-DASRPWLCYWILHSLELLDEPIPQIVATDVCQFLE 134 Query: 77 SCQHECGGVSASIGHDPHLLYTLSAVQILTLY---DSIHVINVDKVVAYVQSLQKEDGSF 133 CQ GG G PHL T +AV L + ++ +VIN +K++ Y+ SL++ DGSF Sbjct: 135 LCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSF 194 Query: 134 AGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQ 193 + GE+D R ++CA + +L + E E++ C N++GG G PG E+H G Sbjct: 195 LMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGY 254 Query: 194 IYCCTGFLAITSQLHQVNSDLLGWWLCERQLP-SGGLNGRPEKLPDVCYSWWVLASLKII 252 +C L I + +N L W+ RQ+ GG GR KL D CYS+W L ++ Sbjct: 255 TFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLL 314 Query: 253 GRL------------HWI-DREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLS 299 R HW+ ++ L+ +IL C GG D+PG D +HT + ++GLS Sbjct: 315 HRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLS 374 Query: 300 L----------------LGEEQIKPVSPVFCM-PEEVLQ 321 + + E ++P PV+ + P++V+Q Sbjct: 375 IAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQ 413 >4YDO-B nrPDB Length = 587 Score = 99.4 bits (246), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 74/266 (27%), Positives = 124/266 (46%), Gaps = 51/266 (19%) Query: 83 GGVSASIGHDPHLLYTLSAVQILTLYDSIHVI-NVDKVVA-YVQSLQKED-----GSFAG 135 GG + +GH L T +A+ L L D ++ N+ +++ ++ +L+K SF Sbjct: 246 GGGNNQLGH---LASTYAAILTLILTDQYELLDNLRELIRDWLLTLKKRSSCGSGASFIM 302 Query: 136 DIWGEIDTRFSFCAVATLALLG------------KLDAINVEKAIEFVLSCMNFDGGFGC 183 GE+D R ++CA+ + LL +LD + ++ ++ SC ++GGF Sbjct: 303 HENGEMDARSTYCALIIINLLNLTNYEENSSSPEELDPL-IDGVENWLNSCQTYEGGFSN 361 Query: 184 RPGSESHAGQIYCC-TGFLAITSQLHQVN-------------SDLLGWWLCERQLPSGGL 229 P +E+H G YC + + Q + LL W + + GG+ Sbjct: 362 IPNTEAHGGYTYCALASYFLLYDNRKQFSSGSTSSLSNSVCWEKLLEWSVHRQHELEGGV 421 Query: 230 NGRPEKLPDVCYSWWV-----LASLKIIG---------RLHWIDREKLRSFILACQDEET 275 +GR KL D CY +W+ L L I+ + D EKLR ++L +E+ Sbjct: 422 DGRTNKLVDACYGFWIGGLSPLLQLIIMNSSQGQGQQQEVKVFDEEKLRQYLLIIAQDES 481 Query: 276 GGFADRPGDMVDPFHTLFGIAGLSLL 301 GGF D+PG VD +HT + ++GLS+L Sbjct: 482 GGFKDKPGKQVDYYHTNYSLSGLSIL 507 >4LNB-B nrPDB Length = 519 Score = 94.7 bits (234), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 81/290 (27%), Positives = 126/290 (43%), Gaps = 38/290 (13%) Query: 50 VYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLY- 108 VYW L + L+G+ +E ++ + Q+ GG+ G H+ + +AV + + Sbjct: 155 VYWALAGLCLLGEDVTRFRERVISTFTAAQNSTGGIGGGHGQMSHVASSYAAVLSIAMVG 214 Query: 109 --DSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEK 166 ++ +I+ + ++ L++ DG F GE D R ++CA+ ALL A+ E Sbjct: 215 GEEAFKLIDRKAMWKWLGKLKQPDGGFTVCEGGEEDVRGAYCAMVVHALLDLPLALPPEA 274 Query: 167 AI-------------EFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQV--- 210 E++ C ++GG PGSE+H +C L + + V Sbjct: 275 EARQNGLETFTDGLPEYLSRCQTYEGGISGSPGSEAHGAYAFCALACLCLLGRPEVVVPR 334 Query: 211 --NSDLLGWWLCERQL-PSGGLNGRPEKLPDVCYSWWV----------------LASLKI 251 N L WL RQ P GG +GR KL D CYS WV LA K Sbjct: 335 YMNIATLLPWLSARQYAPEGGFSGRTNKLVDGCYSHWVGNCWPLVQAALDGTQPLAGPKR 394 Query: 252 IGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLL 301 + RE L +IL+C + GG D+PG D +HT + + GLS + Sbjct: 395 SSVGNLYSREGLTRYILSCCQCKLGGLRDKPGKHPDSYHTCYALTGLSTV 444 Score = 36.6 bits (83), Expect = 0.017, Method: Compositional matrix adjust. Identities = 50/243 (20%), Positives = 90/243 (37%), Gaps = 50/243 (20%) Query: 116 VDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAI-----NVEKAIEF 170 D + Y+ Q +G +G E ++FCA+A L LLG+ + + N+ + + Sbjct: 285 TDGLPEYLSRCQTYEGGISGSPGSEAHGAYAFCALACLCLLGRPEVVVPRYMNIATLLPW 344 Query: 171 VLSCMNF--DGGFGCRP------------------------GSESHAGQIYCCTGFLAIT 204 LS + +GGF R G++ AG G L Sbjct: 345 -LSARQYAPEGGFSGRTNKLVDGCYSHWVGNCWPLVQAALDGTQPLAGPKRSSVGNL--- 400 Query: 205 SQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLR 264 L + L Q GGL +P K PD ++ + L L + H+ + Sbjct: 401 ----YSREGLTRYILSCCQCKLGGLRDKPGKHPDSYHTCYALTGLSTVQYYHYCTDSSVS 456 Query: 265 SFILACQDEETGGFADR--PGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQR 322 S +D+ + F+ + P D + G+ +++ P P+F +P + + Sbjct: 457 S-----KDDFSSAFSWKHDPNFASDGQGSDIGV----FTENDRLVPFHPIFVIPHKSAED 507 Query: 323 VNV 325 + V Sbjct: 508 IRV 510 >3DRA-B nrPDB Length = 390 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 76/293 (25%), Positives = 117/293 (39%), Gaps = 66/293 (22%) Query: 93 PHLLYTLSAV-QILTLYDSIH-VINVDKVVAYVQSLQKEDGSFAGDI------------- 137 P+L TL A+ +L L H +IN K++ ++ Q +DG G Sbjct: 92 PNLSSTLFALYNLLILKSPYHTIINRKKIMNFLCKCQVKDGINKGGFVPTLYYNEENGDY 151 Query: 138 --WGEIDTRFSFCAVATLALLGKLDA-------------INVEKAIEFVLSCMNFDGGFG 182 +GE D R + A+ L+ D I++ +F+L +N +GGF Sbjct: 152 KQYGEPDLRVCYMALLIRHLMKYDDNNNNNNREDSNETDIDLISLQQFILDRININGGFS 211 Query: 183 CRPGSESHAGQIYCCTGFLAITSQ-LHQVNSDLLGWWLCERQLPS--------------- 226 ESH G +C L + + L ++ S WL RQ+ Sbjct: 212 STIMDESHLGFTFCAIASLKLLNYPLEKLKST--KEWLIHRQVDYPENLYPKDGNGDGNG 269 Query: 227 -------------GGLNGRPEKLPDVCYSWWVLASLKII--GRLHWIDREKLRSFIL-AC 270 GG NGR KL D CYSWW SL I + +D K ++L Sbjct: 270 NGDNYEYYRNIDIGGFNGRENKLSDTCYSWWCTGSLYNIDVNFIKLVDLNKAEDYLLNKT 329 Query: 271 QDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQ--IKPVSPVFCMPEEVLQ 321 Q++ GGF P DP H+ +A LSL E+ ++ ++P+ + +E Q Sbjct: 330 QNQLFGGFGRDPDSTPDPMHSYLALASLSLWNHEKFALQEINPILTITKESYQ 382 >3SFX-B nrPDB Length = 520 Score = 74.7 bits (182), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 90/378 (23%), Positives = 143/378 (37%), Gaps = 96/378 (25%) Query: 15 PDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSG------------VYWGLTVMDLMG- 61 P+ L+ E Y S K++ ++ S + ++ G V+W + +DL+G Sbjct: 47 PNALVSEHGKRY--SGLRKQEHTQFLASSFFQLPGKFVSLDASRPWLVFWTVHSLDLLGV 104 Query: 62 QLHRMNKEEILVFIKSCQHECGGVSASIGHD--PHLLYTLSAVQILTLYDSIHVINVDK- 118 L + K+ ++ + GG + PHLL T ++V L + + K Sbjct: 105 ALDQGTKDRVVSTLLHFLSPKGGFGGGPANSQIPHLLPTYASVCSLAIAGNDSSTGGWKD 164 Query: 119 VVAYVQSL-------QKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFV 171 + A QS+ ++ DG F GE+D R ++C + LL + + +FV Sbjct: 165 LAAARQSIYEFFMRCKRPDGGFVVCEGGEVDVRGTYCLLVVATLLDIITPELLHNVDKFV 224 Query: 172 LSCMNFDGGFGCR--------------PGS---------ESHAGQIYCC--TGFLAITSQ 206 +C ++GGF C P S E+H G C + FL + Sbjct: 225 SACQTYEGGFACASFPFPSVVPSTSAFPTSEPSCRVSMAEAHGGYTSCSLNSHFLLTSVP 284 Query: 207 LHQVNSDL-----LGWWLCERQLP--SGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWID 259 L + L W + ++ P GG GR KL D CYSWWV + L + Sbjct: 285 LPSFPLSIDANAALRWTVLQQGEPIEGGGFRGRTNKLVDGCYSWWVGGGAPVAEEL--VR 342 Query: 260 REKLR------------------------------------SFILACQDE-ETGGFADRP 282 REK R + + A QD TGG D+P Sbjct: 343 REKSRKVKKSRIEVFEEEKEGDWEDVPPIPPIFNRVALQEFTLVAAQQDPGSTGGLRDKP 402 Query: 283 GDMVDPFHTLFGIAGLSL 300 G D +HT ++GLS+ Sbjct: 403 GKRPDQYHTCNNLSGLSI 420 >1UMP-A nrPDB Length = 631 Score = 32.0 bits (71), Expect = 0.34, Method: Compositional matrix adjust. Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Query: 109 DSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLG-KLDAINVEKA 167 D+ VI + V Y++ QK DGS+ G WG + V+ L +G ++KA Sbjct: 463 DAWKVIR--RAVEYLKREQKPDGSWFGR-WGVNYLYGTGAVVSALKAVGIDTREPYIQKA 519 Query: 168 IEFVLSCMNFDGGFG--CR 184 +++V N DGG+G CR Sbjct: 520 LDWVEQHQNPDGGWGEDCR 538 >5JOZ-A nrPDB Length = 515 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 13/40 (32%), Positives = 25/40 (62%), Gaps = 1/40 (2%) Query: 242 SWWVLASLKII-GRLHWIDREKLRSFILACQDEETGGFAD 280 +W+V S++ I G+++++ + SF+L D ETG F + Sbjct: 122 NWYVDPSIEFIDGKMYFLSPDNQGSFLLGVMDPETGTFVE 161 >1W6K-A nrPDB Length = 732 Score = 28.9 bits (63), Expect = 3.2, Method: Compositional matrix adjust. Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 16/123 (13%) Query: 120 VAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKL-----DAINVEKAIEFVLSC 174 + + + Q+ DGS+ G WG T ++ + A +G+ V +A +F+LS Sbjct: 564 LEFCRRQQRADGSWEGS-WGVCFTYGTWFGLEAFACMGQTYRDGTACAEVSRACDFLLSR 622 Query: 175 MNFDGGFG-----C--RPGSESHAGQIY-CCTGFLAITSQLH-QVNSDLLG-WWLCERQL 224 DGG+G C R +S QI+ C + + + H + + G L E+QL Sbjct: 623 QMADGGWGEDFESCEERRYVQSAQSQIHNTCWAMMGLMAVRHPDIEAQERGVRCLLEKQL 682 Query: 225 PSG 227 P+G Sbjct: 683 PNG 685 >2QFC-A nrPDB Length = 293 Score = 27.7 bits (60), Expect = 7.1, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 7/49 (14%) Query: 26 YIASYGSKKDDYEYCMSEYLRMSG-------VYWGLTVMDLMGQLHRMN 67 Y+A+Y KK DYEYC+ E ++ VY L + + + ++ N Sbjct: 120 YVAAYVLKKVDYEYCILELKKLLNQQLTGIDVYQNLYIENAIANIYAEN 168 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3HXF-B nrPDB 499 e-142 2ZIR-B nrPDB 387 e-108 1N4R-B nrPDB 363 e-101 4LNB-B nrPDB 319 1e-87 3SFX-B nrPDB 315 1e-86 4YDO-B nrPDB 273 1e-73 3DRA-B nrPDB 254 5e-68 Sequences not found previously or not previously below threshold: 1UMP-A nrPDB 40 0.001 2CIC-A nrPDB 34 0.13 3B5I-A nrPDB 30 1.4 5ZOV-A nrPDB 30 1.5 3MSU-A nrPDB 29 2.3 5VTM-X nrPDB 29 2.6 3Q6J-A nrPDB 29 3.1 4F10-A nrPDB 29 3.5 3ENJ-A nrPDB 27 9.0 >3HXF-B nrPDB Length = 331 Score = 499 bits (1284), Expect = e-142, Method: Composition-based stats. Identities = 331/331 (100%), Positives = 331/331 (100%) Query: 1 MGTQQKDVTIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLM 60 MGTQQKDVTIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLM Sbjct: 1 MGTQQKDVTIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLM 60 Query: 61 GQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVV 120 GQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVV Sbjct: 61 GQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVV 120 Query: 121 AYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGG 180 AYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGG Sbjct: 121 AYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGG 180 Query: 181 FGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVC 240 FGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVC Sbjct: 181 FGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVC 240 Query: 241 YSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSL 300 YSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSL Sbjct: 241 YSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSL 300 Query: 301 LGEEQIKPVSPVFCMPEEVLQRVNVQPELVS 331 LGEEQIKPVSPVFCMPEEVLQRVNVQPELVS Sbjct: 301 LGEEQIKPVSPVFCMPEEVLQRVNVQPELVS 331 >2ZIR-B nrPDB Length = 440 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 100/339 (29%), Positives = 164/339 (48%), Gaps = 36/339 (10%) Query: 18 LLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQ-LHRMNKEEILVFIK 76 L EKH Y+ + D C+ + R YW L ++L+ + + ++ ++ F++ Sbjct: 76 LQREKHFHYLKRGLRQLTDAYECL-DASRPWLCYWILHSLELLDEPIPQIVATDVCQFLE 134 Query: 77 SCQHECGGVSASIGHDPHLLYTLSAVQILTLY---DSIHVINVDKVVAYVQSLQKEDGSF 133 CQ GG G PHL T +AV L + ++ +VIN +K++ Y+ SL++ DGSF Sbjct: 135 LCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSF 194 Query: 134 AGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQ 193 + GE+D R ++CA + +L + E E++ C N++GG G PG E+H G Sbjct: 195 LMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGY 254 Query: 194 IYCCTGFLAITSQLHQVNSDLLGWWLCERQLP-SGGLNGRPEKLPDVCYSWWVLASLKII 252 +C L I + +N L W+ RQ+ GG GR KL D CYS+W L ++ Sbjct: 255 TFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLL 314 Query: 253 GRL------------HW-IDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLS 299 R HW ++ L+ +IL C GG D+PG D +HT + ++GLS Sbjct: 315 HRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLS 374 Query: 300 L----------------LGEEQIKPVSPVFCM-PEEVLQ 321 + + E ++P PV+ + P++V+Q Sbjct: 375 IAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQ 413 >1N4R-B nrPDB Length = 377 Score = 363 bits (931), Expect = e-101, Method: Composition-based stats. Identities = 97/338 (28%), Positives = 160/338 (47%), Gaps = 35/338 (10%) Query: 18 LLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKS 77 L ++H + + Y E R++ ++ L+ +D++ L +NK++I+ +I S Sbjct: 20 FLRDRHVRFFQRCLQVLPE-RYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYS 78 Query: 78 CQ----------HECG-------GVSASIGHDP---------HLLYTLSAV-QILTLYDS 110 Q CG G+ + +P H+ T + + ++ L D Sbjct: 79 LQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDD 138 Query: 111 IHVINVDKVVAYVQSLQKEDGSFAGDIWG-EIDTRFSFCAVATLALLGKLDAINVEKAIE 169 + ++ + +A +++LQ EDGSF G E D RF +CA +L ++++KAI Sbjct: 139 LSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAIS 198 Query: 170 FVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNS----DLLGWWLCERQLP 225 ++ M++D G G ESH G +C L + +L +V S + + W RQ Sbjct: 199 YIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQ-- 256 Query: 226 SGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDM 285 G +GRP K D CYS+WV A+LK++ + + EK R++IL+ QD GGFA P Sbjct: 257 QNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSH 316 Query: 286 VDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRV 323 D H FGI GLSL+ E I V P + +R+ Sbjct: 317 PDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERL 354 >4LNB-B nrPDB Length = 519 Score = 319 bits (817), Expect = 1e-87, Method: Composition-based stats. Identities = 84/323 (26%), Positives = 134/323 (41%), Gaps = 39/323 (12%) Query: 17 TLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIK 76 L + H +Y+ + + R VYW L + L+G+ +E ++ Sbjct: 123 ALQRKDHLEYLYDSLEDYP-ASFVALDASRPWMVYWALAGLCLLGEDVTRFRERVISTFT 181 Query: 77 SCQHECGGVSASIGHDPHLLYTLSAVQILTLY---DSIHVINVDKVVAYVQSLQKEDGSF 133 + Q+ GG+ G H+ + +AV + + ++ +I+ + ++ L++ DG F Sbjct: 182 AAQNSTGGIGGGHGQMSHVASSYAAVLSIAMVGGEEAFKLIDRKAMWKWLGKLKQPDGGF 241 Query: 134 AGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAI-------------EFVLSCMNFDGG 180 GE D R ++CA+ ALL A+ E E++ C ++GG Sbjct: 242 TVCEGGEEDVRGAYCAMVVHALLDLPLALPPEAEARQNGLETFTDGLPEYLSRCQTYEGG 301 Query: 181 FGCRPGSESHAGQIYCCTGFLAITSQLHQV-----NSDLLGWWLCERQL-PSGGLNGRPE 234 PGSE+H +C L + + V N L WL RQ P GG +GR Sbjct: 302 ISGSPGSEAHGAYAFCALACLCLLGRPEVVVPRYMNIATLLPWLSARQYAPEGGFSGRTN 361 Query: 235 KLPDVCYSWWVL----------------ASLKIIGRLHWIDREKLRSFILACQDEETGGF 278 KL D CYS WV A K + RE L +IL+C + GG Sbjct: 362 KLVDGCYSHWVGNCWPLVQAALDGTQPLAGPKRSSVGNLYSREGLTRYILSCCQCKLGGL 421 Query: 279 ADRPGDMVDPFHTLFGIAGLSLL 301 D+PG D +HT + + GLS + Sbjct: 422 RDKPGKHPDSYHTCYALTGLSTV 444 >3SFX-B nrPDB Length = 520 Score = 315 bits (808), Expect = 1e-86, Method: Composition-based stats. Identities = 85/382 (22%), Positives = 137/382 (35%), Gaps = 96/382 (25%) Query: 15 PDTLLLEKHADYIASYGSKKDDYEYCMSEYL------------RMSGVYWGLTVMDLMG- 61 P+ L+ E Y S K++ ++ S + R V+W + +DL+G Sbjct: 47 PNALVSEHGKRY--SGLRKQEHTQFLASSFFQLPGKFVSLDASRPWLVFWTVHSLDLLGV 104 Query: 62 QLHRMNKEEILVFIKSCQHECGGVSASIGHD--PHLLYTLSAVQILTLYDSIHVINVDK- 118 L + K+ ++ + GG + PHLL T ++V L + + K Sbjct: 105 ALDQGTKDRVVSTLLHFLSPKGGFGGGPANSQIPHLLPTYASVCSLAIAGNDSSTGGWKD 164 Query: 119 -------VVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFV 171 + + ++ DG F GE+D R ++C + LL + + +FV Sbjct: 165 LAAARQSIYEFFMRCKRPDGGFVVCEGGEVDVRGTYCLLVVATLLDIITPELLHNVDKFV 224 Query: 172 LSCMNFDGGFGCR-----------------------PGSESHAGQIYCCT--GFLAITSQ 206 +C ++GGF C +E+H G C FL + Sbjct: 225 SACQTYEGGFACASFPFPSVVPSTSAFPTSEPSCRVSMAEAHGGYTSCSLNSHFLLTSVP 284 Query: 207 LHQVNSDL-----LGWWLCERQLP--SGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWID 259 L + L W + ++ P GG GR KL D CYSWWV + L + Sbjct: 285 LPSFPLSIDANAALRWTVLQQGEPIEGGGFRGRTNKLVDGCYSWWVGGGAPVAEEL--VR 342 Query: 260 REKLR------------------------------------SFILACQDE-ETGGFADRP 282 REK R + + A QD TGG D+P Sbjct: 343 REKSRKVKKSRIEVFEEEKEGDWEDVPPIPPIFNRVALQEFTLVAAQQDPGSTGGLRDKP 402 Query: 283 GDMVDPFHTLFGIAGLSLLGEE 304 G D +HT ++GLS+ + Sbjct: 403 GKRPDQYHTCNNLSGLSIAQHK 424 >4YDO-B nrPDB Length = 587 Score = 273 bits (697), Expect = 1e-73, Method: Composition-based stats. Identities = 80/348 (22%), Positives = 143/348 (41%), Gaps = 60/348 (17%) Query: 16 DTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMG----QLHRMNKEEI 71 + ++ H YI S Y + + +YW L L+ ++++ + I Sbjct: 164 NYFYIDAHLKYILSSLIDPMPSGYQVLDVNHSWMIYWLLNSYYLIQNPTMEINQSILDLI 223 Query: 72 LVFIKSCQH--------ECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVIN--VDKVVA 121 + I C + G+ HL T +A+ L L D +++ + + Sbjct: 224 VNKITKCINYGDSLSGVPFDGIGGGNNQLGHLASTYAAILTLILTDQYELLDNLRELIRD 283 Query: 122 YVQSLQKED-----GSFAGDIWGEIDTRFSFCAVATLALLG------------KLDAINV 164 ++ +L+K SF GE+D R ++CA+ + LL +LD + + Sbjct: 284 WLLTLKKRSSCGSGASFIMHENGEMDARSTYCALIIINLLNLTNYEENSSSPEELDPL-I 342 Query: 165 EKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTG-FLAITSQLHQVN------------ 211 + ++ SC ++GGF P +E+H G YC + + Q + Sbjct: 343 DGVENWLNSCQTYEGGFSNIPNTEAHGGYTYCALASYFLLYDNRKQFSSGSTSSLSNSVC 402 Query: 212 -SDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIG--------------RLH 256 LL W + + GG++GR KL D CY +W+ ++ + Sbjct: 403 WEKLLEWSVHRQHELEGGVDGRTNKLVDACYGFWIGGLSPLLQLIIMNSSQGQGQQQEVK 462 Query: 257 WIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEE 304 D EKLR ++L +E+GGF D+PG VD +HT + ++GLS+L Sbjct: 463 VFDEEKLRQYLLIIAQDESGGFKDKPGKQVDYYHTNYSLSGLSILEHS 510 >3DRA-B nrPDB Length = 390 Score = 254 bits (648), Expect = 5e-68, Method: Composition-based stats. Identities = 86/385 (22%), Positives = 143/385 (37%), Gaps = 83/385 (21%) Query: 16 DTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEI---- 71 + LL+ KH + + +++ +Y+ L + L+ + N+E I Sbjct: 2 NQLLINKHEKFFNRCLIGLPSTAQ-SEDSNKLAIIYFCLHGLQLIQKFQFTNQELIYYRN 60 Query: 72 --LVFIKSCQHECGGVSASIGHD----------PHLLYTLSAV-QILTLYDSIH-VINVD 117 + ++ +S H P+L TL A+ +L L H +IN Sbjct: 61 FIINQFMIENNQI--ISFRSTHYFQKTNQKYDCPNLSSTLFALYNLLILKSPYHTIINRK 118 Query: 118 KVVAYVQSLQKEDGSFAGDI---------------WGEIDTRFSFCAVATLALLGKLD-- 160 K++ ++ Q +DG G +GE D R + A+ L+ D Sbjct: 119 KIMNFLCKCQVKDGINKGGFVPTLYYNEENGDYKQYGEPDLRVCYMALLIRHLMKYDDNN 178 Query: 161 -----------AINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQ 209 I++ +F+L +N +GGF ESH G +C L + + + Sbjct: 179 NNNNREDSNETDIDLISLQQFILDRININGGFSSTIMDESHLGFTFCAIASLKLLNYPLE 238 Query: 210 VNSDLLGWWLCERQLPS----------------------------GGLNGRPEKLPDVCY 241 WL RQ+ GG NGR KL D CY Sbjct: 239 -KLKSTKEWLIHRQVDYPENLYPKDGNGDGNGNGDNYEYYRNIDIGGFNGRENKLSDTCY 297 Query: 242 SWWVLASLKII--GRLHWIDREKLRSFIL-ACQDEETGGFADRPGDMVDPFHTLFGIAGL 298 SWW SL I + +D K ++L Q++ GGF P DP H+ +A L Sbjct: 298 SWWCTGSLYNIDVNFIKLVDLNKAEDYLLNKTQNQLFGGFGRDPDSTPDPMHSYLALASL 357 Query: 299 SLLGEEQ--IKPVSPVFCMPEEVLQ 321 SL E+ ++ ++P+ + +E Q Sbjct: 358 SLWNHEKFALQEINPILTITKESYQ 382 >1UMP-A nrPDB Length = 631 Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 48/120 (40%), Gaps = 7/120 (5%) Query: 66 MNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQS 125 + + ++ SCQ + G + + + + + D + ++K+ Y+ Sbjct: 13 RTLDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHIL--DRVDRDRMEKIRRYLLH 70 Query: 126 LQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKL-DAINVEKAIEFVLSCMNFDGGFGCR 184 Q+EDG++A G D + A L +G D ++KA+ F+ S GG Sbjct: 71 EQREDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEEPMQKALRFIQS----QGGIESS 126 >2CIC-A nrPDB Length = 229 Score = 33.5 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 33/78 (42%), Gaps = 11/78 (14%) Query: 71 ILVFIKSCQHECGGVSASIGHDPHLLYTLS------AVQILTLYDSIHVINVDKVVAYVQ 124 IL I+ H+C G ++G LL T + + LY + I + + + Q Sbjct: 129 ILNDIELIIHKCSGFGFNLGE---LLSTYFTLAIKCGLNLEILYKTY--IGKNVLNIFRQ 183 Query: 125 SLQKEDGSFAGDIWGEID 142 + +DGS+ G+ D Sbjct: 184 NNGYKDGSYKKTWNGKED 201 >3B5I-A nrPDB Length = 374 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 5/56 (8%) Query: 261 EKLRSFILACQDEETGGFADR--PGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFC 314 + RS+ +A G F R P +D FH+ F + LS + E S + Sbjct: 127 DGNRSYFVA---GVPGSFYRRLFPARTIDFFHSAFSLHWLSQVPESVTDRRSAAYN 179 >5ZOV-A nrPDB Length = 465 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 18/45 (40%) Query: 79 QHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYV 123 Q GG SIGH + ++ L D ++ K+ ++ Sbjct: 182 QAVTGGAGFSIGHQQQIASWIAVKLAPKLGDKNDTVDKMKLPKWL 226 >3MSU-A nrPDB Length = 427 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 37/102 (36%), Gaps = 7/102 (6%) Query: 21 EKHADYIASYGSKKDDYEYCMSEYLRM----SGVYWGLTVMDLMGQLHRMNKEEILVFIK 76 E YI Y + E+ + + Y + + + ++EI+ + Sbjct: 62 ESKITYIDGGKGVLLHRGYPIEEWTQKSNYRTLCYALIYGELPTDEQVKSFRQEIINKMP 121 Query: 77 SCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDK 118 C+H ++A H + ++ V +L + H+ N K Sbjct: 122 VCEHVKAAIAAMPQHTHPMSSLIAGVNVLA---AEHIHNGQK 160 >5VTM-X nrPDB Length = 273 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 5/50 (10%), Positives = 16/50 (32%) Query: 54 LTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQ 103 L + + ++ + + + ++ + Q+ G A A Sbjct: 90 LATLGMKEEIVQGLPDRLADWLDADQNPQGEQGAEDNQYLLEAPAYRAAN 139 >3Q6J-A nrPDB Length = 523 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 19/46 (41%), Gaps = 2/46 (4%) Query: 282 PGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCM--PEEVLQRVNV 325 P + D HT + ++ L + EE + + P + +NV Sbjct: 384 PKNYPDFLHTHYEVSFLGMGEEEARAAGHEIVTIKMPPDTENGLNV 429 >4F10-A nrPDB Length = 353 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 11/87 (12%), Positives = 26/87 (29%), Gaps = 4/87 (4%) Query: 52 WGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLY--D 109 + L+ M + +E ++ ++ + + + Sbjct: 145 FALSTMMAEPNVDTAQRERVVKWLNRVARHQTSFPGGDTSCCNNASYWRGQEATIIGVIS 204 Query: 110 SIHVINVDKVVAYVQSLQK--EDGSFA 134 + + YVQ++ EDGSF Sbjct: 205 KDDELFRWGLGRYVQAMGLINEDGSFV 231 >3ENJ-A nrPDB Length = 437 Score = 27.4 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 32/93 (34%), Gaps = 9/93 (9%) Query: 52 WGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTL-------SAVQI 104 W +++G E L+ + H H HL+ + A + Sbjct: 209 WSHNFTNMLGYTDAQFTE--LMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAM 266 Query: 105 LTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDI 137 L +H + +V+ ++ LQKE G D Sbjct: 267 NGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDE 299 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.132 0.354 Lambda K H 0.267 0.0405 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,451,649 Number of Sequences: 36641 Number of extensions: 470005 Number of successful extensions: 1108 Number of sequences better than 10.0: 17 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 957 Number of HSP's gapped (non-prelim): 50 length of query: 331 length of database: 10,336,785 effective HSP length: 97 effective length of query: 234 effective length of database: 6,782,608 effective search space: 1587130272 effective search space used: 1587130272 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 59 (27.4 bits)