BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q08602 (567 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1DCE-A nrPDB 1149 0.0 3C72-A nrPDB 473 e-134 1O1S-A nrPDB 79 5e-15 2BED-A nrPDB 79 5e-15 2H6F-A nrPDB 78 1e-14 4YDO-A nrPDB 62 5e-10 3Q78-A nrPDB 60 3e-09 4MBG-A nrPDB 54 3e-07 6HKW-A nrPDB 47 2e-05 3JB9-j nrPDB 38 0.015 5LJ5-W nrPDB 37 0.022 5LFN-A nrPDB 37 0.029 3CIG-A nrPDB 37 0.031 3A7C-A nrPDB 35 0.11 1M9S-A nrPDB 34 0.15 6HLU-A nrPDB 33 0.26 4PUF-A nrPDB 33 0.41 6GFF-I nrPDB 33 0.42 5YQ5-A nrPDB 33 0.46 1KOH-A nrPDB 32 0.59 6ICZ-o nrPDB 32 0.71 4WYK-A nrPDB 32 0.93 4R6F-A nrPDB 32 1.1 5YXM-A nrPDB 31 1.4 5D3I-A nrPDB 31 1.4 2JJ9-A nrPDB 31 1.8 3O7P-A nrPDB 31 1.9 3MKD-A nrPDB 30 1.9 6O00-A nrPDB 30 2.0 5Y3M-A nrPDB 30 2.1 3A79-B nrPDB 30 2.3 4R08-A nrPDB 30 3.0 1XCD-A nrPDB 30 3.3 1JL5-A nrPDB 29 4.6 1RR9-A nrPDB 29 4.7 2ZQM-A nrPDB 29 6.5 3ULU-A nrPDB 29 6.8 2IZ1-A nrPDB 28 9.3 3T6Q-A nrPDB 28 9.4 >1DCE-A nrPDB Length = 567 Score = 1149 bits (2971), Expect = 0.0, Method: Compositional matrix adjust. Identities = 567/567 (100%), Positives = 567/567 (100%) Query: 1 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 60 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP Sbjct: 1 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 60 Query: 61 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL 120 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL Sbjct: 61 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL 120 Query: 121 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS 180 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS Sbjct: 121 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS 180 Query: 181 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAE 240 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAE Sbjct: 181 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAE 240 Query: 241 PHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWRTPDGRNRPSHVW 300 PHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWRTPDGRNRPSHVW Sbjct: 241 PHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWRTPDGRNRPSHVW 300 Query: 301 LCDLPAASLNDQLPQHTFRVIWTGSDSQKECVLLKDRPECWCRDSATDEQLFRCELSVEK 360 LCDLPAASLNDQLPQHTFRVIWTGSDSQKECVLLKDRPECWCRDSATDEQLFRCELSVEK Sbjct: 301 LCDLPAASLNDQLPQHTFRVIWTGSDSQKECVLLKDRPECWCRDSATDEQLFRCELSVEK 360 Query: 361 STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVDPMRAA 420 STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVDPMRAA Sbjct: 361 STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVDPMRAA 420 Query: 421 YLDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPP 480 YLDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPP Sbjct: 421 YLDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPP 480 Query: 481 ALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNL 540 ALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNL Sbjct: 481 ALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNL 540 Query: 541 QGNSLCQEEGIQERLAEMLPSVSSILT 567 QGNSLCQEEGIQERLAEMLPSVSSILT Sbjct: 541 QGNSLCQEEGIQERLAEMLPSVSSILT 567 >3C72-A nrPDB Length = 334 Score = 473 bits (1218), Expect = e-134, Method: Compositional matrix adjust. Identities = 237/237 (100%), Positives = 237/237 (100%) Query: 1 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 60 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP Sbjct: 5 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 64 Query: 61 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL 120 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL Sbjct: 65 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL 124 Query: 121 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS 180 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS Sbjct: 125 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS 184 Query: 181 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLG 237 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLG Sbjct: 185 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLG 241 Score = 186 bits (473), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 143/322 (44%), Positives = 175/322 (54%), Gaps = 49/322 (15%) Query: 129 LELCARFLEADERNFHCWDYRRFV---------AAQAAVAPAEELAFTDSLITRNFSNYS 179 LEL ++ L A+ W+ RR V ++A EL F +S + N +Y Sbjct: 53 LELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYG 112 Query: 180 SWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRA 239 +WH+R LL RLPE +ELEL D + W Y R++ +A Sbjct: 113 TWHHRCWLL------------SRLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQA 160 Query: 240 EPHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWRTPDGRNRPSHV 299 ++ ++ ++ FS + R LL + P S P GR P +V Sbjct: 161 AVAPA---EELAFTDSLITRNFSNYSSWHYR-SCLLPQLHPQPDS----GPQGR-LPENV 211 Query: 300 WLCDLPAASLNDQLPQHTFRVIWTGSDSQKECVLLKDRPECWCRDSATDEQLFRCELSVE 359 L +L +L Q+ F +D + R W + + RCELSVE Sbjct: 212 LLKEL-------ELVQNAF-----FTDPNDQSAWFYHR---WLLGAGSG----RCELSVE 252 Query: 360 KSTVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVDPMRA 419 KSTVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVDPMRA Sbjct: 253 KSTVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVDPMRA 312 Query: 420 AYLDDLRSKFLLENSVLKMEYA 441 AYLDDLRSKFLLENSVLKMEYA Sbjct: 313 AYLDDLRSKFLLENSVLKMEYA 334 >1O1S-A nrPDB Length = 380 Score = 79.3 bits (194), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 53/197 (26%), Positives = 94/197 (47%), Gaps = 20/197 (10%) Query: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESC 99 Q E E +LT + N T+W+ RR +L+ L+ + ++ E+ ++ + Sbjct: 111 QRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKD---------LQEEMNYITAI 161 Query: 100 LRVNPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVA 159 + PK+Y WHHR L+ L +P ++ELE A L D +N+H W +R++V + + Sbjct: 162 IEEQPKNYQVWHHRRVLVEWLKDP--SQELEFIADILNQDAKNYHAWQHRQWVIQEFRLW 219 Query: 160 PAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAF 219 EL + D L+ + N S W+ R ++ S G VL +E++ Sbjct: 220 D-NELQYVDQLLKEDVRNNSVWNQRHFVI--------SNTTGYSDRAVLEREVQYTLEMI 270 Query: 220 FTDPNDQSAWFYHRWLL 236 P+++SAW Y + +L Sbjct: 271 KLVPHNESAWNYLKGIL 287 >2BED-A nrPDB Length = 313 Score = 79.0 bits (193), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 53/197 (26%), Positives = 94/197 (47%), Gaps = 20/197 (10%) Query: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESC 99 Q E E +LT + N T+W+ RR +L+ L+ + ++ E+ ++ + Sbjct: 55 QRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKD---------LQEEMNYITAI 105 Query: 100 LRVNPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVA 159 + PK+Y WHHR L+ L +P ++ELE A L D +N+H W +R++V + + Sbjct: 106 IEEQPKNYQVWHHRRVLVEWLKDP--SQELEFIADILNQDAKNYHAWQHRQWVIQEFRLW 163 Query: 160 PAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAF 219 EL + D L+ + N S W+ R ++ S G VL +E++ Sbjct: 164 D-NELQYVDQLLKEDVRNNSVWNQRHFVI--------SNTTGYSDRAVLEREVQYTLEMI 214 Query: 220 FTDPNDQSAWFYHRWLL 236 P+++SAW Y + +L Sbjct: 215 KLVPHNESAWNYLKGIL 231 >2H6F-A nrPDB Length = 382 Score = 77.8 bits (190), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 20/197 (10%) Query: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESC 99 Q E E +LT + N T+W+ RR +L+ L+ + + E+ ++ + Sbjct: 108 QRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKD---------LHEEMNYITAI 158 Query: 100 LRVNPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVA 159 + PK+Y WHHR L+ L +P ++ELE A L D +N+H W +R++V + + Sbjct: 159 IEEQPKNYQVWHHRRVLVEWLRDP--SQELEFIADILNQDAKNYHAWQHRQWVIQEFKLW 216 Query: 160 PAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAF 219 EL + D L+ + N S W+ R ++ S G VL +E++ Sbjct: 217 D-NELQYVDQLLKEDVRNNSVWNQRYFVI--------SNTTGYNDRAVLEREVQYTLEMI 267 Query: 220 FTDPNDQSAWFYHRWLL 236 P+++SAW Y + +L Sbjct: 268 KLVPHNESAWNYLKGIL 284 >4YDO-A nrPDB Length = 329 Score = 62.4 bits (150), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 54/210 (25%), Positives = 90/210 (42%), Gaps = 25/210 (11%) Query: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESC 99 +A E E L +T + T+W R +L++L + EL + E Sbjct: 68 KAEEYSERALHITELGINELASHYTIWIYRFNILKNLPNRN--------LYDELDWCEEI 119 Query: 100 LRVNPKSYGTWHHRCWLLSRLPEPNW-----ARELELCARFLEADERNFHCWDYRRFVAA 154 N K+Y W++R ++ ++ E N RE + L +D +N H W YR+++ Sbjct: 120 ALDNEKNYQIWNYRQLIIGQIMELNNNDFDPYREFPILEAMLSSDPKNHHVWSYRKWLVD 179 Query: 155 QAAV-APAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELE 213 + A+EL+F D +I + N S+W +R LL + +N + +EL Sbjct: 180 TFDLHNDAKELSFVDKVIDTDLKNNSAWSHRFFLL--------FSKKHLATDNTIDEELN 231 Query: 214 LVQNAFFTDPNDQSAWFYHRWLLGRAEPHD 243 V++ P + S W Y LLG E D Sbjct: 232 YVKDKIVKCPQNPSTWNY---LLGIHERFD 258 >3Q78-A nrPDB Length = 349 Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 57/201 (28%), Positives = 82/201 (40%), Gaps = 23/201 (11%) Query: 43 ELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRV 102 E E LELT I+ NP T+W R +L L KS E+ EL + Sbjct: 68 EKSERALELTEIIVRMNPAHYTVWQYRFSLLTSLN--KSLED-------ELRLMNEFAVQ 118 Query: 103 NPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAP-- 160 N KSY WHHR LL R+ + E+E L D +N+H W Y ++ + + Sbjct: 119 NLKSYQVWHHRLLLLDRISPQDPVSEIEYIHGSLLPDPKNYHTWAYLHWLYSHFSTLGRI 178 Query: 161 -----AEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELV 215 EL + + ++ + N S+W +R L S P L EL + Sbjct: 179 SEAQWGSELDWCNEMLRVDGRNNSAWGWRWYLRV-------SRPGAETSSRSLQDELIYI 231 Query: 216 QNAFFTDPNDQSAWFYHRWLL 236 + P++ SAW Y R L Sbjct: 232 LKSIHLIPHNVSAWNYLRGFL 252 >4MBG-A nrPDB Length = 367 Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 60/244 (24%), Positives = 92/244 (37%), Gaps = 56/244 (22%) Query: 28 YQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVL-------------- 73 Y AT + A E+ E L LT I+ NP T+W R ++L Sbjct: 53 YLEATSYLRAVMAANEMSERALRLTGDIISMNPAHYTVWIYRAKILFALGKDLNEEIEWL 112 Query: 74 -----QHLETEKSPEESAALVKA----------ELGFLESCLRVNPKSYGTWHHRCWLLS 118 +HL+ + L+ + E FL + KSY W +R WL+ Sbjct: 113 NKVALKHLKNYQIWHHRQVLMSSRAHFPTLPPREQDFLMEMFAQDAKSYHVWTYRHWLVR 172 Query: 119 RLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNY 178 + RE++ L+AD RN W++R + P +E F L N + Sbjct: 173 HFKLWDHPREIQDVEALLKADVRNNSAWNHRYML----RFGPRDENEFDAGL--HNTTGP 226 Query: 179 SSWHYRSCLLPQLHPQPDSGPQGRLP---ENVLLKELELVQNAFFTDPNDQSAWFYHRWL 235 SS +GRLP E+++ EL+ Q+ P ++S W Y R + Sbjct: 227 SS------------------EKGRLPVVDEDLVDSELQYSQSRILEAPENRSPWSYARGV 268 Query: 236 LGRA 239 L A Sbjct: 269 LQAA 272 >6HKW-A nrPDB Length = 363 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 34/94 (36%), Positives = 54/94 (57%), Gaps = 4/94 (4%) Query: 458 HLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCN 517 +LE+L + LDL N+++ + L AL LE+L S N L N++GV L RL++L L N Sbjct: 118 NLEELQSLRELDLYDNQIKKIEN-LEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVN 176 Query: 518 NRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGI 551 N++ + I+ L + +L +L L N + E I Sbjct: 177 NKI---SKIENLSNLHQLQMLELGSNRIRAIENI 207 Score = 28.9 bits (63), Expect = 6.9, Method: Compositional matrix adjust. Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 23/125 (18%) Query: 441 ADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALEN 500 ++R L+L+H + V+ LE +T LD++ NR++ Sbjct: 255 VNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKK----------------------- 291 Query: 501 VDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEMLP 560 ++ +++L LQE + +N L+ + + L L + L+ N L ++ + ++ LP Sbjct: 292 IENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALP 351 Query: 561 SVSSI 565 SV I Sbjct: 352 SVRQI 356 >3JB9-j nrPDB Length = 239 Score = 37.7 bits (86), Expect = 0.015, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 3/97 (3%) Query: 468 LDLSHNRLRALPPALAALRCLEVLQASDNALENV--DGVANLPRLQELLLCNNRLQQSAA 525 +D + N +R L ++ L+ L +N + + D LP L+ L L N LQ+ A Sbjct: 46 IDFTDNDIRYLG-NFPRMKRLQTLLCGNNRITAIAPDIGKVLPNLKTLSLAQNHLQEIAD 104 Query: 526 IQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEMLPSV 562 + PL SCP+L L+ N + Q++ + L +PS+ Sbjct: 105 LDPLASCPQLTNLSCIDNPVAQKQYYRLYLIWRIPSL 141 >5LJ5-W nrPDB Length = 238 Score = 37.0 bits (84), Expect = 0.022, Method: Compositional matrix adjust. Identities = 40/147 (27%), Positives = 68/147 (46%), Gaps = 9/147 (6%) Query: 421 YLDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTH-LDLSHNRLRALP 479 Y+D K+ ++ V+ +R L L ++ L+ L TH LDL++N L + Sbjct: 15 YVDHFNGKYNVDKCVI------LRDLQLETDSESMPSSLKHLTKPTHILDLTNNDL-IMI 67 Query: 480 PALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPR-LVLL 538 P L+ + L N + VDG +Q L L NN +++ +Q L PR L L Sbjct: 68 PDLSRRDDIHTLLLGRNNIVEVDGRLLPMNVQNLTLSNNSIRRFEDLQRLRRAPRTLKNL 127 Query: 539 NLQGNSLCQEEGIQERLAEMLPSVSSI 565 L GN +C +E + ++P + ++ Sbjct: 128 TLIGNQVCHLANYREHVLRLVPHLETL 154 >5LFN-A nrPDB Length = 337 Score = 36.6 bits (83), Expect = 0.029, Method: Compositional matrix adjust. Identities = 45/141 (31%), Positives = 63/141 (44%), Gaps = 12/141 (8%) Query: 424 DLRSKFLLENSVLKMEYA---DVRVLHLAHKDLTVLCH-----LEQLLLVTHLDLSHNRL 475 DLR +L EN++ ++ DV L H D L L +L +V L LSHN L Sbjct: 150 DLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPL 209 Query: 476 RALPP-ALAAL-RCLEVLQASDNALENVDGVA--NLPRLQELLLCNNRLQQSAAIQPLVS 531 +++P A + R LE L + LE A + L+ + L NNRL Q + P S Sbjct: 210 KSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDS 269 Query: 532 CPRLVLLNLQGNSLCQEEGIQ 552 L L N CQ G++ Sbjct: 270 LETLALTNNPWKCTCQLRGLR 290 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 3/63 (4%) Query: 446 LHLAHKDLTVL--CHLEQLLLVTHLDLSHNRLRALPPA-LAALRCLEVLQASDNALENVD 502 L+L+H D+ VL + L +T+L L HN++ LP L+ L L +LQ ++N + + Sbjct: 82 LYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELR 141 Query: 503 GVA 505 A Sbjct: 142 AGA 144 >3CIG-A nrPDB Length = 697 Score = 36.6 bits (83), Expect = 0.031, Method: Compositional matrix adjust. Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Query: 465 VTHLDLSHNRLRALPPA-LAALRCLEVLQASDNALENVDG--VANLPRLQELLLCNNRLQ 521 +T L+L+HN+LR LPP L +L A N++ ++ LP L+ L L +N L Sbjct: 27 ITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNSISKLEPELCQILPLLKVLNLQHNELS 86 Query: 522 QSAAIQPLVSCPRLVLLNLQGNSL 545 Q + Q V C L L+L NS+ Sbjct: 87 Q-ISDQTFVFCTNLTELDLMSNSI 109 >3A7C-A nrPDB Length = 580 Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust. Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 35/156 (22%) Query: 431 LENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLL----VTHLDLSHN------------- 473 L+NS K + ++ L L+ L + ++LL +T LD+S N Sbjct: 377 LKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSCQWPE 436 Query: 474 RLRALPPALAALRC--------LEVLQASDNALENVDGVANLPRLQELLLCNNRLQQ--S 523 ++R L + +R LEVL S+N L++ LPRLQEL + N+L+ Sbjct: 437 KMRFLNLSSTGIRVVKTCIPQTLEVLDVSNNNLDSFSLF--LPRLQELYISRNKLKTLPD 494 Query: 524 AAIQPLVSCPRLVLLNLQGNSL-CQEEGIQERLAEM 558 A++ P+ L+++ + N L +GI +RL + Sbjct: 495 ASLFPV-----LLVMKIASNQLKSVPDGIFDRLTSL 525 >1M9S-A nrPDB Length = 605 Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust. Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Query: 447 HLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVAN 506 H D+ L HL QL L L +N++ + L+ L L+ L DN + ++ +A Sbjct: 118 HNGISDINGLVHLPQL---ESLYLGNNKITDIT-VLSRLTKLDTLSLEDNQISDIVPLAG 173 Query: 507 LPRLQELLLCNNRLQQSAAIQPL 529 L +LQ L L N + A+ L Sbjct: 174 LTKLQNLYLSKNHISDLRALAGL 196 Score = 32.3 bits (72), Expect = 0.52, Method: Compositional matrix adjust. Identities = 35/167 (20%), Positives = 70/167 (41%), Gaps = 34/167 (20%) Query: 410 TLKAVDPMRAAYLDDLRSKFLLEN--------SVLKMEYADVRVLHLAHKDLTVLCHLEQ 461 T+ P++ + DD ++ + +N +V + E + + + D+ + ++ Sbjct: 4 TITVSTPIKQIFPDDAFAETIKDNLKKKSVTDAVTQNELNSIDQIIANNSDIKSVQGIQY 63 Query: 462 LLLVTHLDLSHNRLRALPPALAALRCLEVL----------------------QASDNALE 499 L VT L L+ N+L + P L L+ L L N + Sbjct: 64 LPNVTKLFLNGNKLTDIKP-LTNLKNLGWLFLDENKIKDLSSLKDLKKLKSLSLEHNGIS 122 Query: 500 NVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLC 546 +++G+ +LP+L+ L L NN++ I L +L L+L+ N + Sbjct: 123 DINGLVHLPQLESLYLGNNKITD---ITVLSRLTKLDTLSLEDNQIS 166 >6HLU-A nrPDB Length = 974 Score = 33.5 bits (75), Expect = 0.26, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 4/94 (4%) Query: 453 LTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQE 512 +T + L L ++ L L N++ + P LA+L L +L N + ++ + +L L E Sbjct: 103 ITDISPLASLNSLSMLWLDRNQITDIAP-LASLNSLSMLWLFGNKISDIAPLESLKSLTE 161 Query: 513 LLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLC 546 L L +N++ I PL S L L+L GN++ Sbjct: 162 LQLSSNQITD---IAPLASLKSLTELSLSGNNIS 192 >4PUF-A nrPDB Length = 637 Score = 32.7 bits (73), Expect = 0.41, Method: Compositional matrix adjust. Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 16/103 (15%) Query: 465 VTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANL-PRLQELLLCNNRLQQS 523 +THL++ N L ALP L L+ L+A +NAL ++ A+L P LQ L + N++ Sbjct: 178 ITHLNVQSNSLTALPETLPP--GLKTLEAGENALTSLP--ASLPPELQVLDVSKNQI--- 230 Query: 524 AAIQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEMLPSVSSIL 566 + P P + L++ N+L L E LP+ I+ Sbjct: 231 -TVLPETLPPTITTLDVSRNALTN-------LPENLPAALQIM 265 >6GFF-I nrPDB Length = 618 Score = 32.7 bits (73), Expect = 0.42, Method: Compositional matrix adjust. Identities = 32/87 (36%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 467 HLDLSHNRLRAL-PPALAALRCLEVLQASDNALE-----NVDGVANLPRLQELLLCNNRL 520 HLDLS N + L P A AL LE L + N L + G+ LPR+ L L N L Sbjct: 58 HLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSL 117 Query: 521 QQSAAIQPLVSCPRLVLLNLQGNSLCQ 547 + L P L L+L NSL + Sbjct: 118 YSGLLERLLGEAPSLHTLSLAENSLTR 144 Score = 32.3 bits (72), Expect = 0.58, Method: Compositional matrix adjust. Identities = 34/87 (39%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 459 LEQLLLVTHLDLSHNRLRALPPA-LAALRCLEVLQASDNALENVD-GVANLPRLQELLLC 516 LE L + L+LS N LR L +L CL +L S NALE ++ G L L+ LLL Sbjct: 316 LEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQ 375 Query: 517 NNRLQQSAAIQPLVSCPRLVLLNLQGN 543 N L+ + L LNLQGN Sbjct: 376 GNALRDLPPYT-FANLASLQRLNLQGN 401 Score = 29.6 bits (65), Expect = 3.7, Method: Compositional matrix adjust. Identities = 24/55 (43%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Query: 468 LDLSHNRLRALPPALAALRCLEVLQASDNALENVD--GVANLPRLQELLLCNNRL 520 LDLSHN L L AL L L NAL ++ ANL LQ L L NR+ Sbjct: 349 LDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRV 403 >5YQ5-A nrPDB Length = 430 Score = 32.7 bits (73), Expect = 0.46, Method: Compositional matrix adjust. Identities = 35/134 (26%), Positives = 58/134 (43%), Gaps = 36/134 (26%) Query: 455 VLCHLEQLLLVTHLDLSHNRLRALPPALAA----------------------LRCLEVLQ 492 + +E+L+ L+L NRL ++PP L + L L L+ Sbjct: 205 IFAKMEKLM---QLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLR 261 Query: 493 ASDNALENVD-GVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGI 551 S N L+++ + NLP + EL + +N+L+Q+ I PR NL+ L E Sbjct: 262 MSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYI------PR----NLEHLYLQNNEIE 311 Query: 552 QERLAEMLPSVSSI 565 + L M PS+ + Sbjct: 312 KMNLTVMCPSIDPL 325 >1KOH-A nrPDB Length = 277 Score = 32.3 bits (72), Expect = 0.59, Method: Compositional matrix adjust. Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Query: 506 NLPRLQELLLCNNRLQQSAAIQPLV-SCPRLVLLNLQGNSLCQE 548 N+P L L L NNRL + + +V P L +LNL GN L E Sbjct: 168 NIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSE 211 >6ICZ-o nrPDB Length = 255 Score = 32.0 bits (71), Expect = 0.71, Method: Compositional matrix adjust. Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 7/86 (8%) Query: 468 LDLSHNRLRALPPALAALRCLEVLQASDNAL----ENVDGVANLPRLQELLLCNNRLQQS 523 +D S N +R L LR L+ L ++N + E +D LP L EL+L NN L + Sbjct: 47 IDFSDNEIRKLD-GFPLLRRLKTLLVNNNRICRIGEGLDQA--LPCLTELILTNNSLVEL 103 Query: 524 AAIQPLVSCPRLVLLNLQGNSLCQEE 549 + PL S L L++ N + ++ Sbjct: 104 GDLDPLASLKSLTYLSILRNPVTNKK 129 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 28/54 (51%) Query: 467 HLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRL 520 LDL ++ + A L + + SDN + +DG L RL+ LL+ NNR+ Sbjct: 23 ELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRI 76 >4WYK-A nrPDB Length = 461 Score = 31.6 bits (70), Expect = 0.93, Method: Compositional matrix adjust. Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Query: 506 NLPRLQELLLCNNRLQQSAAIQPLV-SCPRLVLLNLQGNSLCQE 548 N+P L L L NNRL + + +V P L +LNL GN L E Sbjct: 169 NIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSE 212 >4R6F-A nrPDB Length = 331 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 39/118 (33%), Positives = 57/118 (48%), Gaps = 5/118 (4%) Query: 434 SVLKMEY-ADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPAL-AALRCLEVL 491 SV ++Y +VR L L L + L++L + L+LS+N+L LP + L L L Sbjct: 55 SVQGIQYLPNVRYLALGGNKLHDISALKELTNLGWLNLSNNQLETLPQGVFEKLTNLTTL 114 Query: 492 QASDNALENV-DGV-ANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQ 547 S+N L ++ GV L L L L NN + + Q L L LNL N+L + Sbjct: 115 NLSNNQLTSLPQGVFERLASLTTLNLSNNNI-ANINDQMLEGLTNLTTLNLSHNNLAR 171 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 2/74 (2%) Query: 485 LRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNS 544 L ++ + A+++ +++V G+ LP ++ L L N+L +A++ L + L L N Q + Sbjct: 40 LNSIDQIIANNSDIKSVQGIQYLPNVRYLALGGNKLHDISALKELTNLGWLNLSNNQLET 99 Query: 545 LCQEEGIQERLAEM 558 L Q G+ E+L + Sbjct: 100 LPQ--GVFEKLTNL 111 >5YXM-A nrPDB Length = 203 Score = 31.2 bits (69), Expect = 1.4, Method: Compositional matrix adjust. Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 453 LTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQE 512 ++ L +E L + L L N ++ + A LE L S N + ++ G+ L L+ Sbjct: 68 ISSLSGMENLRI---LSLGRNLIKKIENLDAVADTLEELWISYNQIASLSGIEKLVNLRV 124 Query: 513 LLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE 548 L + NN++ I L + +L L L GN L + Sbjct: 125 LYMSNNKITNWGEIDKLAALDKLEDLLLAGNPLYND 160 >5D3I-A nrPDB Length = 568 Score = 31.2 bits (69), Expect = 1.4, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 27/116 (23%) Query: 431 LENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLL----VTHLDLSHN------------- 473 L+NS K + ++ L L+ L + ++LL +T LD+S N Sbjct: 355 LKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSCQWPE 414 Query: 474 RLRALPPALAALRC--------LEVLQASDNALENVDGVANLPRLQELLLCNNRLQ 521 ++R L + +R LEVL S+N L++ LPRLQEL + N+L+ Sbjct: 415 KMRFLNLSSTGIRVVKTCIPQTLEVLDVSNNNLDSFSLF--LPRLQELYISRNKLK 468 >2JJ9-A nrPDB Length = 788 Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust. Identities = 24/70 (34%), Positives = 30/70 (42%), Gaps = 11/70 (15%) Query: 38 KRQAGE----LDESVLELTSQILGANPDF-------ATLWNCRREVLQHLETEKSPEESA 86 ++ AGE D++ L S + G NP + R V QHL EKS Sbjct: 371 EKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSSSRD 430 Query: 87 ALVKAELGFL 96 ALVKA G L Sbjct: 431 ALVKALYGRL 440 >3O7P-A nrPDB Length = 438 Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 230 FYHRWLLGRAEPHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWRT 289 F WL+ R PH VL + CL F+ G +G + L + A +S+++ T Sbjct: 313 FTGTWLISRFAPHKVLAAYALIAMALCLISAFA-----GGHVGLIALTLCSAFMSIQYPT 367 >3MKD-A nrPDB Length = 692 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 29/68 (42%), Gaps = 11/68 (16%) Query: 38 KRQAGE----LDESVLELTSQILGANPDF-------ATLWNCRREVLQHLETEKSPEESA 86 ++ AGE D++ L S + G NP + R V QHL EKS Sbjct: 359 EKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSSSRD 418 Query: 87 ALVKAELG 94 ALVKA G Sbjct: 419 ALVKALYG 426 >6O00-A nrPDB Length = 820 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Query: 467 HLDLSHNRLRALPPALAALRCLEVLQASDNALENVDG-VANLPRLQELLLCNNRLQ 521 +LDLSHN L LP + L+ L+ L + N +E + + +L+ L L NN LQ Sbjct: 689 YLDLSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQ 744 >5Y3M-A nrPDB Length = 801 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 17/123 (13%) Query: 437 KMEYADVRVLHLAHKDLT--------VLCHLEQLLLVTHLDLSHNRLRA-LPPALAAL-R 486 K+ A +R L + L+ LC + L + LDLS N L LP L L + Sbjct: 572 KLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLDLSENHLHTLLPRHLDNLPK 631 Query: 487 CLEVLQASDN--ALENVDGVANLPRLQELLLCNNRLQ--QSAAIQPLVSCPRLVLLNLQG 542 L L+ DN A N + LPRL+ L L N+L+ + ++ P + RL L++ Sbjct: 632 SLRQLRLRDNNLAFFNWSSLTVLPRLEALDLAGNQLKALSNGSLPPGI---RLQKLDVSS 688 Query: 543 NSL 545 NS+ Sbjct: 689 NSI 691 >3A79-B nrPDB Length = 562 Score = 30.4 bits (67), Expect = 2.3, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 2/56 (3%) Query: 465 VTHLDLSHNRLRALPPALAALRCLEVLQASDNALENV-DGVAN-LPRLQELLLCNN 518 V LDL +NR+ ++P + L+ L+ L + N L++V DGV + L LQ + L +N Sbjct: 452 VKVLDLHNNRIMSIPKDVTHLQALQELNVASNQLKSVPDGVFDRLTSLQYIWLHDN 507 >4R08-A nrPDB Length = 811 Score = 30.0 bits (66), Expect = 3.0, Method: Compositional matrix adjust. Identities = 39/141 (27%), Positives = 65/141 (46%), Gaps = 17/141 (12%) Query: 439 EYADVRVLHLAHKDLTVLC---HLEQLLLVTHLDLSHNRLRAL--------PPALAALRC 487 + +++VL+L+H ++ L +LE LV L S NRL L L+ Sbjct: 560 NFTNLKVLNLSHNNIYTLTDKYNLESKSLV-ELVFSGNRLDILWNDDDNRYISIFKGLKN 618 Query: 488 LEVLQASDNALENV--DGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSL 545 L L S N L+++ + NLP L N+ + + L PRL LL+L+GN L Sbjct: 619 LTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKL 678 Query: 546 CQEEGIQERLAEMLPSVSSIL 566 + + L++ S+ ++L Sbjct: 679 L---FLTDSLSDFTSSLRTLL 696 >1XCD-A nrPDB Length = 329 Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust. Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 3/59 (5%) Query: 465 VTHLDLSHNRLRALPPA-LAALRCLEVLQASDNALENVDG--VANLPRLQELLLCNNRL 520 +T L L N++ + A L L L L S N++ VD +AN P L+EL L NN+L Sbjct: 194 LTELHLDGNKITKVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKL 252 >1JL5-A nrPDB Length = 454 Score = 29.3 bits (64), Expect = 4.6, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 3/80 (3%) Query: 443 VRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVD 502 + L +++ L L L+ + +D+ +N L+ LP +L E + A +N LE + Sbjct: 133 LEYLGVSNNQLEKLPELQNSSFLKIIDVDNNSLKKLPDLPPSL---EFIAAGNNQLEELP 189 Query: 503 GVANLPRLQELLLCNNRLQQ 522 + NLP L + NN L++ Sbjct: 190 ELQNLPFLTAIYADNNSLKK 209 >1RR9-A nrPDB Length = 200 Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 4/58 (6%) Query: 47 SVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNP 104 +V+ ++ LG NPDF +R++ H+ +P++ A A L SCL NP Sbjct: 59 TVVRARAEKLGINPDFYE----KRDIHVHVPEGATPKDGPAAGIAMCTALVSCLTGNP 112 >2ZQM-A nrPDB Length = 117 Score = 28.9 bits (63), Expect = 6.5, Method: Composition-based stats. Identities = 20/56 (35%), Positives = 35/56 (62%), Gaps = 5/56 (8%) Query: 3 GRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGA 58 G L VKT++++A A+ E+ + L++ +A + RQ +L+E + ELT+QI A Sbjct: 60 GTLIVKTTKDKAVAELKEKIETLEVRLNALE-----RQEKKLNEKLKELTAQIQSA 110 >3ULU-A nrPDB Length = 694 Score = 28.9 bits (63), Expect = 6.8, Method: Compositional matrix adjust. Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 6/85 (7%) Query: 465 VTHLDLSHNRLRALPPA----LAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRL 520 +T L+L+HN+LR LP A + L L+V + + LE + LP L+ L L +N L Sbjct: 37 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLE-PELCQKLPMLKVLNLQHNEL 95 Query: 521 QQSAAIQPLVSCPRLVLLNLQGNSL 545 Q + + C L L+L NS+ Sbjct: 96 SQLSD-KTFAFCTNLTELHLMSNSI 119 >2IZ1-A nrPDB Length = 474 Score = 28.5 bits (62), Expect = 9.3, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 21/32 (65%) Query: 25 LKLYQSATQAVFQKRQAGELDESVLELTSQIL 56 L L + QA+F++ GELD ++E+T ++L Sbjct: 211 LGLSNAEIQAIFEEWNEGELDSYLIEITKEVL 242 >3T6Q-A nrPDB Length = 606 Score = 28.1 bits (61), Expect = 9.4, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 2/53 (3%) Query: 468 LDLSHNRLRALPPALAALRCLEVLQASDNALENV--DGVANLPRLQELLLCNN 518 LDL+ L LP L L L+ L S N EN+ +N P L L + N Sbjct: 283 LDLTATHLSELPSGLVGLSTLKKLVLSANKFENLCQISASNFPSLTHLSIKGN 335 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1DCE-A nrPDB 892 0.0 3C72-A nrPDB 334 1e-91 3Q78-A nrPDB 231 6e-61 4YDO-A nrPDB 229 3e-60 1O1S-A nrPDB 224 8e-59 2BED-A nrPDB 221 6e-58 2H6F-A nrPDB 221 9e-58 4MBG-A nrPDB 216 2e-56 6HKW-A nrPDB 128 7e-30 Sequences not found previously or not previously below threshold: 6HLU-A nrPDB 57 3e-08 5YXM-A nrPDB 55 8e-08 6GFF-I nrPDB 49 7e-06 6O00-A nrPDB 46 6e-05 6ICZ-o nrPDB 46 6e-05 5MX0-A nrPDB 44 1e-04 3CIG-A nrPDB 44 2e-04 5LJ5-W nrPDB 44 2e-04 3ULU-A nrPDB 42 5e-04 5LFN-A nrPDB 42 5e-04 5Y3M-A nrPDB 42 0.001 5YQ5-A nrPDB 41 0.001 3T6Q-A nrPDB 41 0.002 3JB9-j nrPDB 40 0.002 2Z7X-B nrPDB 40 0.004 2FT3-A nrPDB 39 0.004 3B2D-A nrPDB 39 0.005 4R08-A nrPDB 39 0.005 3A7C-A nrPDB 39 0.005 5ZSN-B nrPDB 37 0.017 3A79-B nrPDB 37 0.030 1M9S-A nrPDB 35 0.079 3RG1-A nrPDB 35 0.12 5GY2-A nrPDB 34 0.21 5D3I-A nrPDB 33 0.31 1XCD-A nrPDB 33 0.37 5Y3K-A nrPDB 33 0.41 1JL5-A nrPDB 32 0.56 2Z7X-A nrPDB 32 0.84 4WSS-A nrPDB 32 0.90 4ECN-A nrPDB 31 1.1 4WYK-A nrPDB 31 1.5 3NTV-A nrPDB 31 1.8 1HXR-A nrPDB 31 2.0 4QDH-A nrPDB 31 2.1 1KOH-A nrPDB 30 2.6 5J5V-A nrPDB 30 3.0 4AIB-A nrPDB 30 3.0 5CLR-A nrPDB 30 3.5 3WPI-A nrPDB 29 4.8 5AJ4-Ba nrPDB 29 5.4 3LY6-A nrPDB 29 5.5 2R91-A nrPDB 29 6.7 5OOM-5 nrPDB 29 7.7 5UJB-A nrPDB 28 9.2 >1DCE-A nrPDB Length = 567 Score = 892 bits (2305), Expect = 0.0, Method: Composition-based stats. Identities = 567/567 (100%), Positives = 567/567 (100%) Query: 1 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 60 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP Sbjct: 1 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 60 Query: 61 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL 120 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL Sbjct: 61 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL 120 Query: 121 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS 180 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS Sbjct: 121 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS 180 Query: 181 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAE 240 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAE Sbjct: 181 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAE 240 Query: 241 PHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWRTPDGRNRPSHVW 300 PHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWRTPDGRNRPSHVW Sbjct: 241 PHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWRTPDGRNRPSHVW 300 Query: 301 LCDLPAASLNDQLPQHTFRVIWTGSDSQKECVLLKDRPECWCRDSATDEQLFRCELSVEK 360 LCDLPAASLNDQLPQHTFRVIWTGSDSQKECVLLKDRPECWCRDSATDEQLFRCELSVEK Sbjct: 301 LCDLPAASLNDQLPQHTFRVIWTGSDSQKECVLLKDRPECWCRDSATDEQLFRCELSVEK 360 Query: 361 STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVDPMRAA 420 STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVDPMRAA Sbjct: 361 STVLQSELESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVDPMRAA 420 Query: 421 YLDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPP 480 YLDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPP Sbjct: 421 YLDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPP 480 Query: 481 ALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNL 540 ALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNL Sbjct: 481 ALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNL 540 Query: 541 QGNSLCQEEGIQERLAEMLPSVSSILT 567 QGNSLCQEEGIQERLAEMLPSVSSILT Sbjct: 541 QGNSLCQEEGIQERLAEMLPSVSSILT 567 >3C72-A nrPDB Length = 334 Score = 334 bits (855), Expect = 1e-91, Method: Composition-based stats. Identities = 237/238 (99%), Positives = 237/238 (99%) Query: 1 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 60 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP Sbjct: 5 MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANP 64 Query: 61 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL 120 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL Sbjct: 65 DFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRL 124 Query: 121 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS 180 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS Sbjct: 125 PEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSS 184 Query: 181 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGR 238 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLG Sbjct: 185 WHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGA 242 Score = 283 bits (724), Expect = 1e-76, Method: Composition-based stats. Identities = 146/350 (41%), Positives = 180/350 (51%), Gaps = 50/350 (14%) Query: 101 RVNPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAP 160 K Y + + + E + + LEL ++ L A+ W+ RR V Sbjct: 26 EQKLKLYQSATQAVFQKRQAGELDESV-LELTSQILGANPDFATLWNCRREVLQHLETEK 84 Query: 161 A---------EELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKE 211 + EL F +S + N +Y +WH+R LL RLPE +E Sbjct: 85 SPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLL------------SRLPEPNWARE 132 Query: 212 LELVQNAFFTDPNDQSAWFYHRWLLGRAEPHDVLCCVHVSREEACLSVCFSRPLTVGSRM 271 LEL D + W Y R+ A V ++ ++ ++ FS + R Sbjct: 133 LELCARFLEADERNFHCWDYRRF---VAAQAAVAPAEELAFTDSLITRNFSNYSSWHYR- 188 Query: 272 GTLLLMVDEAPLSVEWRTPDGRNRPSHVWLCDLPAASLNDQLPQHTFRVIWTGSDSQKEC 331 LL + P S P GR P +V L +L +L Q+ F +D + Sbjct: 189 SCLLPQLHPQPDS----GPQGR-LPENVLLKEL-------ELVQNAF-----FTDPNDQS 231 Query: 332 VLLKDRPECWCRDSATDEQLFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILL 391 R W + + RCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILL Sbjct: 232 AWFYHR---WLLGAGSG----RCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILL 284 Query: 392 MRALDPLLYEKETLQYFSTLKAVDPMRAAYLDDLRSKFLLENSVLKMEYA 441 MRALDPLLYEKETLQYFSTLKAVDPMRAAYLDDLRSKFLLENSVLKMEYA Sbjct: 285 MRALDPLLYEKETLQYFSTLKAVDPMRAAYLDDLRSKFLLENSVLKMEYA 334 >3Q78-A nrPDB Length = 349 Score = 231 bits (589), Expect = 6e-61, Method: Composition-based stats. Identities = 56/216 (25%), Positives = 83/216 (38%), Gaps = 23/216 (10%) Query: 28 YQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAA 87 Y+ A E E LELT I+ NP T+W R +L L Sbjct: 53 YKDAMDYFRAIAAKEEKSERALELTEIIVRMNPAHYTVWQYRFSLLTSLNKS-------- 104 Query: 88 LVKAELGFLESCLRVNPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWD 147 ++ EL + N KSY WHHR LL R+ + E+E L D +N+H W Sbjct: 105 -LEDELRLMNEFAVQNLKSYQVWHHRLLLLDRISPQDPVSEIEYIHGSLLPDPKNYHTWA 163 Query: 148 YRRFVAAQAAVAP-------AEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQ 200 Y ++ + + EL + + ++ + N S+W +R L S P Sbjct: 164 YLHWLYSHFSTLGRISEAQWGSELDWCNEMLRVDGRNNSAWGWRWYLRV-------SRPG 216 Query: 201 GRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLL 236 L EL + + P++ SAW Y R L Sbjct: 217 AETSSRSLQDELIYILKSIHLIPHNVSAWNYLRGFL 252 >4YDO-A nrPDB Length = 329 Score = 229 bits (583), Expect = 3e-60, Method: Composition-based stats. Identities = 55/222 (24%), Positives = 93/222 (41%), Gaps = 25/222 (11%) Query: 28 YQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAA 87 Y+ + +A E E L +T + T+W R +L++L Sbjct: 56 YKQIMGILLSLMKAEEYSERALHITELGINELASHYTIWIYRFNILKNLPNRN------- 108 Query: 88 LVKAELGFLESCLRVNPKSYGTWHHRCWLLSRLPEPN-----WARELELCARFLEADERN 142 + EL + E N K+Y W++R ++ ++ E N RE + L +D +N Sbjct: 109 -LYDELDWCEEIALDNEKNYQIWNYRQLIIGQIMELNNNDFDPYREFPILEAMLSSDPKN 167 Query: 143 FHCWDYRRFVAAQAAV-APAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQG 201 H W YR+++ + A+EL+F D +I + N S+W +R LL + Sbjct: 168 HHVWSYRKWLVDTFDLHNDAKELSFVDKVIDTDLKNNSAWSHRFFLL--------FSKKH 219 Query: 202 RLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAEPHD 243 +N + +EL V++ P + S W Y LLG E D Sbjct: 220 LATDNTIDEELNYVKDKIVKCPQNPSTWNY---LLGIHERFD 258 >1O1S-A nrPDB Length = 380 Score = 224 bits (571), Expect = 8e-59, Method: Composition-based stats. Identities = 53/210 (25%), Positives = 96/210 (45%), Gaps = 20/210 (9%) Query: 28 YQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAA 87 ++ Q E E +LT + N T+W+ RR +L+ L+ + Sbjct: 99 FRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKD-------- 150 Query: 88 LVKAELGFLESCLRVNPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWD 147 ++ E+ ++ + + PK+Y WHHR L+ L +P ++ELE A L D +N+H W Sbjct: 151 -LQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDP--SQELEFIADILNQDAKNYHAWQ 207 Query: 148 YRRFVAAQAAVAPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENV 207 +R++V + + EL + D L+ + N S W+ R ++ S G V Sbjct: 208 HRQWVIQEFRLWD-NELQYVDQLLKEDVRNNSVWNQRHFVI--------SNTTGYSDRAV 258 Query: 208 LLKELELVQNAFFTDPNDQSAWFYHRWLLG 237 L +E++ P+++SAW Y + +L Sbjct: 259 LEREVQYTLEMIKLVPHNESAWNYLKGILQ 288 Score = 53.2 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 30/168 (17%), Positives = 57/168 (33%), Gaps = 20/168 (11%) Query: 103 NPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAE 162 + K + + +L R + R +L +E + N+ W +RR + E Sbjct: 96 SEKFRDVYDYFRAVLQR--DERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQE 153 Query: 163 ELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTD 222 E+ + ++I NY WH+R L+ L +ELE + + D Sbjct: 154 EMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPS--------------QELEFIADILNQD 199 Query: 223 PNDQSAWFYHRWLLGRAEPHDVLCCVHVSREEACLSVCFSRPLTVGSR 270 + AW + +W++ D + + L R Sbjct: 200 AKNYHAWQHRQWVIQEFRLWD----NELQYVDQLLKEDVRNNSVWNQR 243 >2BED-A nrPDB Length = 313 Score = 221 bits (563), Expect = 6e-58, Method: Composition-based stats. Identities = 53/210 (25%), Positives = 96/210 (45%), Gaps = 20/210 (9%) Query: 28 YQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAA 87 ++ Q E E +LT + N T+W+ RR +L+ L+ + Sbjct: 43 FRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKD-------- 94 Query: 88 LVKAELGFLESCLRVNPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWD 147 ++ E+ ++ + + PK+Y WHHR L+ L +P ++ELE A L D +N+H W Sbjct: 95 -LQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDP--SQELEFIADILNQDAKNYHAWQ 151 Query: 148 YRRFVAAQAAVAPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENV 207 +R++V + + EL + D L+ + N S W+ R ++ S G V Sbjct: 152 HRQWVIQEFRLWD-NELQYVDQLLKEDVRNNSVWNQRHFVI--------SNTTGYSDRAV 202 Query: 208 LLKELELVQNAFFTDPNDQSAWFYHRWLLG 237 L +E++ P+++SAW Y + +L Sbjct: 203 LEREVQYTLEMIKLVPHNESAWNYLKGILQ 232 Score = 52.8 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 30/168 (17%), Positives = 57/168 (33%), Gaps = 20/168 (11%) Query: 103 NPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAE 162 + K + + +L R + R +L +E + N+ W +RR + E Sbjct: 40 SEKFRDVYDYFRAVLQR--DERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQE 97 Query: 163 ELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTD 222 E+ + ++I NY WH+R L+ L +ELE + + D Sbjct: 98 EMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPS--------------QELEFIADILNQD 143 Query: 223 PNDQSAWFYHRWLLGRAEPHDVLCCVHVSREEACLSVCFSRPLTVGSR 270 + AW + +W++ D + + L R Sbjct: 144 AKNYHAWQHRQWVIQEFRLWD----NELQYVDQLLKEDVRNNSVWNQR 187 >2H6F-A nrPDB Length = 382 Score = 221 bits (562), Expect = 9e-58, Method: Composition-based stats. Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 20/210 (9%) Query: 28 YQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAA 87 ++ Q E E +LT + N T+W+ RR +L+ L+ + Sbjct: 96 FRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKD-------- 147 Query: 88 LVKAELGFLESCLRVNPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEADERNFHCWD 147 + E+ ++ + + PK+Y WHHR L+ L +P ++ELE A L D +N+H W Sbjct: 148 -LHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRDP--SQELEFIADILNQDAKNYHAWQ 204 Query: 148 YRRFVAAQAAVAPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENV 207 +R++V + + EL + D L+ + N S W+ R ++ S G V Sbjct: 205 HRQWVIQEFKLWD-NELQYVDQLLKEDVRNNSVWNQRYFVI--------SNTTGYNDRAV 255 Query: 208 LLKELELVQNAFFTDPNDQSAWFYHRWLLG 237 L +E++ P+++SAW Y + +L Sbjct: 256 LEREVQYTLEMIKLVPHNESAWNYLKGILQ 285 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 50/144 (34%), Gaps = 18/144 (12%) Query: 127 RELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSSWHYRSC 186 R +L +E + N+ W +RR + EE+ + ++I NY WH+R Sbjct: 115 RAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRV 174 Query: 187 LLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAEPHDVLC 246 L+ L +ELE + + D + AW + +W++ + D Sbjct: 175 LVEWLRDPS--------------QELEFIADILNQDAKNYHAWQHRQWVIQEFKLWD--- 217 Query: 247 CVHVSREEACLSVCFSRPLTVGSR 270 + + L R Sbjct: 218 -NELQYVDQLLKEDVRNNSVWNQR 240 >4MBG-A nrPDB Length = 367 Score = 216 bits (550), Expect = 2e-56, Method: Composition-based stats. Identities = 60/246 (24%), Positives = 92/246 (37%), Gaps = 56/246 (22%) Query: 28 YQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVL-------------- 73 Y AT + A E+ E L LT I+ NP T+W R ++L Sbjct: 53 YLEATSYLRAVMAANEMSERALRLTGDIISMNPAHYTVWIYRAKILFALGKDLNEEIEWL 112 Query: 74 -----QHLETEKSPEESAALVKA----------ELGFLESCLRVNPKSYGTWHHRCWLLS 118 +HL+ + L+ + E FL + KSY W +R WL+ Sbjct: 113 NKVALKHLKNYQIWHHRQVLMSSRAHFPTLPPREQDFLMEMFAQDAKSYHVWTYRHWLVR 172 Query: 119 RLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNY 178 + RE++ L+AD RN W++R + P +E F L N + Sbjct: 173 HFKLWDHPREIQDVEALLKADVRNNSAWNHRYML----RFGPRDENEFDAGL--HNTTGP 226 Query: 179 SSWHYRSCLLPQLHPQPDSGPQGRLP---ENVLLKELELVQNAFFTDPNDQSAWFYHRWL 235 SS +GRLP E+++ EL+ Q+ P ++S W Y R + Sbjct: 227 SS------------------EKGRLPVVDEDLVDSELQYSQSRILEAPENRSPWSYARGV 268 Query: 236 LGRAEP 241 L A Sbjct: 269 LQAAGR 274 Score = 29.3 bits (64), Expect = 4.6, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 39/137 (28%), Gaps = 14/137 (10%) Query: 134 RFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHP 193 + Y R V A ++ L T +I+ N ++Y+ W YR+ +L L Sbjct: 45 ATISYSPEYLEATSYLRAVMAANEMSERA-LRLTGDIISMNPAHYTVWIYRAKILFALGK 103 Query: 194 QPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAEPHDVLCCVHVSRE 253 L +E+E + + W + + L+ L Sbjct: 104 D-------------LNEEIEWLNKVALKHLKNYQIWHHRQVLMSSRAHFPTLPPREQDFL 150 Query: 254 EACLSVCFSRPLTVGSR 270 + R Sbjct: 151 MEMFAQDAKSYHVWTYR 167 >6HKW-A nrPDB Length = 363 Score = 128 bits (321), Expect = 7e-30, Method: Composition-based stats. Identities = 37/109 (33%), Positives = 60/109 (55%), Gaps = 4/109 (3%) Query: 443 VRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVD 502 V+ L L + + +LE+L + LDL N+++ + L AL LE+L S N L N++ Sbjct: 103 VKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIEN-LEALTELEILDISFNLLRNIE 161 Query: 503 GVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGI 551 GV L RL++L L NN++ + I+ L + +L +L L N + E I Sbjct: 162 GVDKLTRLKKLFLVNNKI---SKIENLSNLHQLQMLELGSNRIRAIENI 207 Score = 62.1 bits (149), Expect = 7e-10, Method: Composition-based stats. Identities = 39/148 (26%), Positives = 73/148 (49%), Gaps = 5/148 (3%) Query: 422 LDDLRSKFLLENSVLKMEYAD----VRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRA 477 L +L S FL +N + K++ D + VL + LT + L+ L+ + L LSHN + Sbjct: 210 LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEV 269 Query: 478 LPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVL 537 + L L +L + N ++ ++ +++L LQE + +N L+ + + L L Sbjct: 270 IE-GLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLET 328 Query: 538 LNLQGNSLCQEEGIQERLAEMLPSVSSI 565 + L+ N L ++ + ++ LPSV I Sbjct: 329 VYLERNPLQKDPQYRRKVMLALPSVRQI 356 Score = 45.1 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 45/87 (51%), Gaps = 4/87 (4%) Query: 467 HLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAI 526 +DL+H R+ + L+ ++ L N ++ ++ + L L+EL L +N+++ I Sbjct: 83 DVDLNHYRIGKIE-GFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIK---KI 138 Query: 527 QPLVSCPRLVLLNLQGNSLCQEEGIQE 553 + L + L +L++ N L EG+ + Sbjct: 139 ENLEALTELEILDISFNLLRNIEGVDK 165 >6HLU-A nrPDB Length = 974 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 4/103 (3%) Query: 446 LHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVA 505 L L+ ++ + LE L +T L LS N++ + P LA+L+ L LQ S N + ++ + Sbjct: 250 LQLSRNQISDIAPLESLKSLTELQLSSNQITDIAP-LASLKSLTELQLSRNQISDIAPLE 308 Query: 506 NLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE 548 +L L +L L N++ I PL S L L L N + Sbjct: 309 SLNSLSKLWLNGNQITD---IAPLASLNSLTELELSSNQITDI 348 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 4/103 (3%) Query: 446 LHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVA 505 L L+ +++ + LE L +T L LS N++ + P LA+L+ L L S N + ++ + Sbjct: 184 LSLSGNNISDIAPLESLKSLTELSLSSNQITDIAP-LASLKSLTELSLSSNQISDIAPLE 242 Query: 506 NLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE 548 +L L EL L N++ + I PL S L L L N + Sbjct: 243 SLKSLTELQLSRNQI---SDIAPLESLKSLTELQLSSNQITDI 282 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 4/94 (4%) Query: 459 LEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNN 518 LE L +T L LS N++ + P LA+L+ L L S N + ++ + +L L EL L +N Sbjct: 153 LESLKSLTELQLSSNQITDIAP-LASLKSLTELSLSGNNISDIAPLESLKSLTELSLSSN 211 Query: 519 RLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGIQ 552 ++ I PL S L L+L N + ++ Sbjct: 212 QITD---IAPLASLKSLTELSLSSNQISDIAPLE 242 Score = 37.8 bits (86), Expect = 0.014, Method: Composition-based stats. Identities = 31/103 (30%), Positives = 54/103 (52%), Gaps = 4/103 (3%) Query: 446 LHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVA 505 L L +T + L L +T L+LS N++ + P LA+L+ L L S N + ++ +A Sbjct: 316 LWLNGNQITDIAPLASLNSLTELELSSNQITDIAP-LASLKSLSTLWLSSNQISDIAPLA 374 Query: 506 NLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE 548 +L L EL L +N++ + I PL S L +++ N + + Sbjct: 375 SLESLSELSLSSNQI---SDISPLASLNSLTGFDVRRNPIKRL 414 Score = 35.9 bits (81), Expect = 0.047, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Query: 473 NRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSC 532 N++ + P LA+L L +L N + ++ +A+L L L L N++ A ++ L S Sbjct: 101 NQITDISP-LASLNSLSMLWLDRNQITDIAPLASLNSLSMLWLFGNKISDIAPLESLKSL 159 Query: 533 PRLVL 537 L L Sbjct: 160 TELQL 164 >5YXM-A nrPDB Length = 203 Score = 55.2 bits (131), Expect = 8e-08, Method: Composition-based stats. Identities = 26/100 (26%), Positives = 45/100 (45%) Query: 446 LHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVA 505 L L+ ++ + L + + L L N ++ + A LE L S N + ++ G+ Sbjct: 58 LALSTNNIEKISSLSGMENLRILSLGRNLIKKIENLDAVADTLEELWISYNQIASLSGIE 117 Query: 506 NLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSL 545 L L+ L + NN++ I L + +L L L GN L Sbjct: 118 KLVNLRVLYMSNNKITNWGEIDKLAALDKLEDLLLAGNPL 157 >6GFF-I nrPDB Length = 618 Score = 48.6 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Query: 459 LEQLLLVTHLDLSHNRLRALPPA-LAALRCLEVLQASDNALENVD-GVANLPRLQELLLC 516 LE L + L+LS N LR L +L CL +L S NALE ++ G L L+ LLL Sbjct: 316 LEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQ 375 Query: 517 NNRLQQSAAIQPLVSCPRLVLLNLQGNSL 545 N L+ + L LNLQGN + Sbjct: 376 GNALRDLPPY-TFANLASLQRLNLQGNRV 403 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 6/88 (6%) Query: 464 LVTHLDLSHNRLRALPP-ALAALRCLEVLQASDNALE-----NVDGVANLPRLQELLLCN 517 + HLDLS N + L P A AL LE L + N L + G+ LPR+ L L Sbjct: 55 ALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSG 114 Query: 518 NRLQQSAAIQPLVSCPRLVLLNLQGNSL 545 N L + L P L L+L NSL Sbjct: 115 NSLYSGLLERLLGEAPSLHTLSLAENSL 142 Score = 36.7 bits (83), Expect = 0.030, Method: Composition-based stats. Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 10/130 (7%) Query: 425 LRSKFLLENSVLKME---YADVRVLHLAHKDLTVLCHLEQ-----LLLVTHLDLSHNRLR 476 L + L ENS+ ++ + D+ L VL +E L +THL+LS N L Sbjct: 132 LHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLT 191 Query: 477 ALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLV 536 + +L+ L VL S N++E + +L + R + L + PRL+ Sbjct: 192 CISDF--SLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLI 249 Query: 537 LLNLQGNSLC 546 LNL N + Sbjct: 250 YLNLSNNLIR 259 >6O00-A nrPDB Length = 820 Score = 45.5 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 7/113 (6%) Query: 416 PMRAAYLDDLRSKFLLENSVLKMEYA-----DVRVLHLAHKDLTVL-CHLEQLLLVTHLD 469 P++ L +L +L N + K+ +R L L+H +LT L + L + +L Sbjct: 655 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 714 Query: 470 LSHNRLRALPPALAALRCLEVLQASDNALENVDG-VANLPRLQELLLCNNRLQ 521 ++ NR+ ALPP L R L L +N L+++ V L L ++ L NRL+ Sbjct: 715 VTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLE 767 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 57/123 (46%), Gaps = 8/123 (6%) Query: 427 SKFLLENSVLKMEYADVRVLHLAHKDLTVLCH-LEQLLLVTHLDLSHNRLRALPP--ALA 483 +K ++ NS+ KM ++ L L DL + H + L + +DL N L+ + + Sbjct: 579 TKLIVLNSLKKM--VNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQ 636 Query: 484 ALRCLEVLQASDNALENVD-GVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQG 542 L L L+ N + + + NL L+ L L N++++ L C +L L+L Sbjct: 637 HLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPT--QLFYCRKLRYLDLSH 694 Query: 543 NSL 545 N+L Sbjct: 695 NNL 697 Score = 38.2 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 34/119 (28%), Positives = 51/119 (42%), Gaps = 14/119 (11%) Query: 430 LLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRC-L 488 L+E VLK+E D+T+ + QL + L L H + PALA LR L Sbjct: 445 LVELEVLKLELI---------PDVTIPPSIAQLTGLKELWLYHTAAKIEAPALAFLRENL 495 Query: 489 EVLQASDNALENVD-GVANLPRLQELLLCNNRLQQSAA---IQPLVSCPRLVLLNLQGN 543 L ++ + + +L L+EL L N ++ I L RL +L L+ N Sbjct: 496 RALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSN 554 >6ICZ-o nrPDB Length = 255 Score = 45.5 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 3/81 (3%) Query: 466 THLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAA 525 LDL ++ + A L + + SDN + +DG L RL+ LL+ NNR+ + Sbjct: 22 RELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIG- 80 Query: 526 IQPL-VSCPRLVLLNLQGNSL 545 + L + P L L L NSL Sbjct: 81 -EGLDQALPCLTELILTNNSL 100 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 3/97 (3%) Query: 468 LDLSHNRLRALPPALAALRCLEVLQASDNALENV-DGVAN-LPRLQELLLCNNRLQQSAA 525 +D S N +R L LR L+ L ++N + + +G+ LP L EL+L NN L + Sbjct: 47 IDFSDNEIRKLD-GFPLLRRLKTLLVNNNRICRIGEGLDQALPCLTELILTNNSLVELGD 105 Query: 526 IQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEMLPSV 562 + PL S L L++ N + ++ + + +P V Sbjct: 106 LDPLASLKSLTYLSILRNPVTNKKHYRLYVIYKVPQV 142 >5MX0-A nrPDB Length = 362 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 6/106 (5%) Query: 443 VRVLHLAHKDLTVLCH--LEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALEN 500 +R LHL H ++ + + LE L +T L L HN ++ + ++ LR L +L S N L Sbjct: 164 LRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRK 223 Query: 501 VDGVANLPR-LQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSL 545 V LP L++L + +N + P+L+ + L NSL Sbjct: 224 VP--DGLPSALEQLYMEHNNVYTVPD-SYFRGAPKLLYVRLSHNSL 266 Score = 32.4 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 25/123 (20%) Query: 446 LHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVA 505 L+L H +LT + + L L HN++ +P NAL +G+ Sbjct: 146 LYLDHNNLTRMPG-PLPRSLRELHLDHNQISRVPN---------------NAL---EGLE 186 Query: 506 NLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE-EGIQERLAEMLPSVSS 564 NL L L +N +Q+ + + L+LL+L N L + +G+ L ++ ++ Sbjct: 187 NLT---ALYLQHNEIQEVGS--SMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNN 241 Query: 565 ILT 567 + T Sbjct: 242 VYT 244 >3CIG-A nrPDB Length = 697 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 4/89 (4%) Query: 465 VTHLDLSHNRLRALPPA-LAALRCLEVLQASDNALENVDG--VANLPRLQELLLCNNRLQ 521 +T L+L+HN+LR LPP L +L A N++ ++ LP L+ L L +N L Sbjct: 27 ITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNSISKLEPELCQILPLLKVLNLQHNELS 86 Query: 522 QSAAIQPLVSCPRLVLLNLQGNSLCQEEG 550 Q + Q V C L L+L NS+ + + Sbjct: 87 QISD-QTFVFCTNLTELDLMSNSIHKIKS 114 Score = 29.3 bits (64), Expect = 5.0, Method: Composition-based stats. Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 24/120 (20%) Query: 444 RVLHLAHKDLTVLCHLEQLLL----VTHLDLSHNRLRALPPALAALRCLEVLQASDNALE 499 + L L+ ++ L++L+L + ++D+S P LR L +L S+N + Sbjct: 441 KYLQLSTSSFALVPSLQRLMLRRVALKNVDIS-------PSPFRPLRNLTILDLSNNNIA 493 Query: 500 NV-----DGVANLPRLQELLLCNN------RLQQSAAIQPLVSCPRLVLLNLQGNSLCQE 548 N+ +G+ NL L NN R + L L +LNL+ N L + Sbjct: 494 NINEDLLEGLENLEILD--FQHNNLARLWKRANPGGPVNFLKGLSHLHILNLESNGLDEI 551 >5LJ5-W nrPDB Length = 238 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 40/147 (27%), Positives = 68/147 (46%), Gaps = 9/147 (6%) Query: 421 YLDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTH-LDLSHNRLRALP 479 Y+D K+ ++ V+ +R L L ++ L+ L TH LDL++N L +P Sbjct: 15 YVDHFNGKYNVDKCVI------LRDLQLETDSESMPSSLKHLTKPTHILDLTNNDLIMIP 68 Query: 480 PALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPR-LVLL 538 L+ + L N + VDG +Q L L NN +++ +Q L PR L L Sbjct: 69 D-LSRRDDIHTLLLGRNNIVEVDGRLLPMNVQNLTLSNNSIRRFEDLQRLRRAPRTLKNL 127 Query: 539 NLQGNSLCQEEGIQERLAEMLPSVSSI 565 L GN +C +E + ++P + ++ Sbjct: 128 TLIGNQVCHLANYREHVLRLVPHLETL 154 >3ULU-A nrPDB Length = 694 Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 465 VTHLDLSHNRLRALPPA-LAALRCLEVLQASDNALENVDG--VANLPRLQELLLCNNRLQ 521 +T L+L+HN+LR LP A L L N + ++ LP L+ L L +N L Sbjct: 37 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 96 Query: 522 QSAAIQPLVSCPRLVLLNLQGNSLCQEEG 550 Q + + C L L+L NS+ + + Sbjct: 97 QLSD-KTFAFCTNLTELHLMSNSIQKIKN 124 >5LFN-A nrPDB Length = 337 Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 47/144 (32%), Positives = 64/144 (44%), Gaps = 12/144 (8%) Query: 424 DLRSKFLLENSVLKMEYA---DVRVLHLAHKDLTVLCH-----LEQLLLVTHLDLSHNRL 475 DLR +L EN++ ++ DV L H D L L +L +V L LSHN L Sbjct: 150 DLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPL 209 Query: 476 RALP-PALAAL-RCLEVLQASDNALENVDGVANL--PRLQELLLCNNRLQQSAAIQPLVS 531 +++P A + R LE L + LE A L L+ + L NNRL Q + P S Sbjct: 210 KSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDS 269 Query: 532 CPRLVLLNLQGNSLCQEEGIQERL 555 L L N CQ G++ L Sbjct: 270 LETLALTNNPWKCTCQLRGLRRWL 293 >5Y3M-A nrPDB Length = 801 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 14/138 (10%) Query: 422 LDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQ---LLLVTHLDLSHNRLRAL 478 LD R+ + + + ++ L L+H ++ + Q L + LDLSHN+L Sbjct: 455 LDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNGSQFVPLTSLRVLDLSHNKLDLY 514 Query: 479 P-PALAALRCLEVLQASDNAL--------ENVDGVANLPRLQELLLCNNRLQQSAAIQPL 529 + L LE L S N+ N+ VA LP L+ L L +N + + + Sbjct: 515 HGRSFTELPQLEALDLSYNSQPFSMQGVGHNLSFVAQLPSLRYLSLAHNGIH--SRVSQK 572 Query: 530 VSCPRLVLLNLQGNSLCQ 547 +S L L+ GNSL Q Sbjct: 573 LSSASLRALDFSGNSLSQ 590 Score = 38.6 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 42/147 (28%), Positives = 60/147 (40%), Gaps = 26/147 (17%) Query: 420 AYLDDLRSKFLLENSV-----LKMEYADVRVLHLAHKDLT--------VLCHLEQLLLVT 466 A L LR L N + K+ A +R L + L+ LC + L + Sbjct: 550 AQLPSLRYLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLV 609 Query: 467 HLDLSHNRL-----RALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQ 521 LDLS N L R L +LR L + + A N + LPRL+ L L N+L+ Sbjct: 610 QLDLSENHLHTLLPRHLDNLPKSLRQLRLRDNNL-AFFNWSSLTVLPRLEALDLAGNQLK 668 Query: 522 QSAAIQPLVSCP---RLVLLNLQGNSL 545 + S P RL L++ NS+ Sbjct: 669 ALSN----GSLPPGIRLQKLDVSSNSI 691 Score = 36.3 bits (82), Expect = 0.038, Method: Composition-based stats. Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 12/119 (10%) Query: 443 VRVLHLAHKDL-TVLCHLEQLLLVTHLDLSHNRLRALPPA-------LAALRCLEVLQAS 494 +R L LAH + + + + LD S N L + LR L L S Sbjct: 555 LRYLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLDLS 614 Query: 495 DNALENV--DGVANLPR-LQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEG 550 +N L + + NLP+ L++L L +N L L PRL L+L GN L Sbjct: 615 ENHLHTLLPRHLDNLPKSLRQLRLRDNNLAFFN-WSSLTVLPRLEALDLAGNQLKALSN 672 >5YQ5-A nrPDB Length = 430 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 6/100 (6%) Query: 461 QLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENV--DGVANLPRLQELLLCNN 518 ++ + L+L NRL ++PP L + L L +N++ ++ LP+L L + +N Sbjct: 208 KMEKLMQLNLCSNRLESMPPGLPS--SLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHN 265 Query: 519 RLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEM 558 +LQ + + P +V L++ N L Q I L + Sbjct: 266 KLQDIP--YNIFNLPNIVELSVGHNKLKQAFYIPRNLEHL 303 Score = 37.8 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 23/130 (17%) Query: 446 LHLAHKDLTVLCHLEQL-----LLVTHLDLSHNRLRALP-PALAALRCLEVLQASDNALE 499 LHL H +LE+ + L L +N + L A+ L L +L N L Sbjct: 144 LHLEHN------NLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLH 197 Query: 500 NV----DGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGIQERL 555 + A + +L +L LC+NRL+ P L+ L+L+ NS+ I E+ Sbjct: 198 DSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSS----LMYLSLENNSI---SSIPEKY 250 Query: 556 AEMLPSVSSI 565 + LP + ++ Sbjct: 251 FDKLPKLHTL 260 >3T6Q-A nrPDB Length = 606 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 8/112 (7%) Query: 459 LEQLLLVTHLDLSHNRLRALPP---ALAALRCLEVLQASDN--ALENVDGVANLPRLQEL 513 LE L + LDLSH+ + L L L+ L S N + P+L+ L Sbjct: 346 LENLENLRELDLSHDDIETSDCCNLQLRNLSHLQSLNLSYNEPLSLKTEAFKECPQLELL 405 Query: 514 LLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEMLPSVSSI 565 L RL+ A P + L +LNL +SL E+L + LP++ + Sbjct: 406 DLAFTRLKVKDAQSPFQNLHLLKVLNL-SHSLLDISS--EQLFDGLPALQHL 454 Score = 37.8 bits (86), Expect = 0.013, Method: Composition-based stats. Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 7/109 (6%) Query: 442 DVRVLHLAHKDLTV--LCHLE--QLLLVTHLDLSHNRLRALPP-ALAALRCLEVLQASDN 496 ++R L L+H D+ C+L+ L + L+LS+N +L A LE+L + Sbjct: 351 NLRELDLSHDDIETSDCCNLQLRNLSHLQSLNLSYNEPLSLKTEAFKECPQLELLDLAFT 410 Query: 497 ALENVDGVANLPRLQELLLCN--NRLQQSAAIQPLVSCPRLVLLNLQGN 543 L+ D + L L + N + L ++ Q P L LNLQGN Sbjct: 411 RLKVKDAQSPFQNLHLLKVLNLSHSLLDISSEQLFDGLPALQHLNLQGN 459 Score = 32.8 bits (73), Expect = 0.46, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Query: 465 VTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGV--ANLPRLQELLLCNNRLQQ 522 + LDL+ L LP L L L+ L S N EN+ + +N P L L + N + Sbjct: 280 LQELDLTATHLSELPSGLVGLSTLKKLVLSANKFENLCQISASNFPSLTHLSIKGNTKRL 339 Query: 523 SAAIQPLVSCPRLVLLNLQGNSLCQEE--GIQERLAEMLPSVS 563 L + L L+L + + + +Q R L S++ Sbjct: 340 ELGTGCLENLENLRELDLSHDDIETSDCCNLQLRNLSHLQSLN 382 >3JB9-j nrPDB Length = 239 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 31/110 (28%), Positives = 54/110 (49%), Gaps = 7/110 (6%) Query: 459 LEQLLLVTH----LDLSHNRLRALPPALAALRCLEVLQASDNALENV--DGVANLPRLQE 512 +E L ++ +D + N +R L ++ L+ L +N + + D LP L+ Sbjct: 33 IENLGVLRDVHDAIDFTDNDIRYLGN-FPRMKRLQTLLCGNNRITAIAPDIGKVLPNLKT 91 Query: 513 LLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEMLPSV 562 L L N LQ+ A + PL SCP+L L+ N + Q++ + L +PS+ Sbjct: 92 LSLAQNHLQEIADLDPLASCPQLTNLSCIDNPVAQKQYYRLYLIWRIPSL 141 >2Z7X-B nrPDB Length = 520 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 47/185 (25%), Positives = 78/185 (42%), Gaps = 27/185 (14%) Query: 368 LESCKELQELEPENKWCLLTIILLMRALDPLLYEKETLQYFSTLKAVD-PMRAAYLDDLR 426 E+C L ELE T+IL M L L E +L+ +D + D+ + Sbjct: 341 FENCGHLTELE--------TLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKK 392 Query: 427 SKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALR 486 S+L + + +L D C ++ + LDL N+++++P + L Sbjct: 393 GDCSWTKSLLSLNMSS-NIL----TDTIFRCLPPRIKV---LDLHSNKIKSIPKQVVKLE 444 Query: 487 CLEVLQASDNALENV-DGV-ANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNS 544 L+ L + N L++V DG+ L LQ++ L N SCPR+ L+ N Sbjct: 445 ALQELNVASNQLKSVPDGIFDRLTSLQKIWLHTNPWD--------CSCPRIDYLSRWLNK 496 Query: 545 LCQEE 549 Q+E Sbjct: 497 NSQKE 501 >2FT3-A nrPDB Length = 332 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 27/112 (24%), Positives = 46/112 (41%), Gaps = 26/112 (23%) Query: 464 LVTHLDLSHNRLRALPPAL-AALRCLEVLQASDNALEN-------VDGV---------AN 506 + L + NR+R +P + + LR + ++ N LEN DG+ A Sbjct: 124 SLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAK 183 Query: 507 LP--------RLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEG 550 L L EL L +N++ Q+ ++ L+ +L L L N + E Sbjct: 184 LTGIPKDLPETLNELHLDHNKI-QAIELEDLLRYSKLYRLGLGHNQIRMIEN 234 Score = 30.9 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 438 MEYADVRVLHLAHKDLTVLCH--LEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASD 495 + Y+ + L L H + ++ + L L + L L +N+L +P L L+ L+V+ Sbjct: 214 LRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHT 273 Query: 496 NALENV 501 N + V Sbjct: 274 NNITKV 279 Score = 29.3 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 8/103 (7%) Query: 457 CHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLC 516 CHL + S L+A+P ++ L LQ +D + D L L L+L Sbjct: 33 CHLRVVQC------SDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV 86 Query: 517 NNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE-EGIQERLAEM 558 NN++ + + +L L + N L + + L E+ Sbjct: 87 NNKISKIHE-KAFSPLRKLQKLYISKNHLVEIPPNLPSSLVEL 128 >3B2D-A nrPDB Length = 603 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 49/182 (26%), Positives = 75/182 (41%), Gaps = 30/182 (16%) Query: 404 TLQYFSTLKAVDPMRAAYLDDLRSKF----LLENSVLKMEYADVRVLHLAHKDLTVLCHL 459 T Q F+ L+ +D + A +L L S LL+ VL + + D ++ ++ + L HL Sbjct: 270 TFQCFTQLQELD-LTATHLKGLPSGMKGLNLLKKLVLSVNHFD-QLCQISAANFPSLTHL 327 Query: 460 ----------------EQLLLVTHLDLSHNRLRALPP---ALAALRCLEVLQASDNALEN 500 E+L + LDLSHN + A L L L+ L S N Sbjct: 328 YIRGNVKKLHLGVGCLEKLGNLQTLDLSHNDIEASDCCSLQLKNLSHLQTLNLSHNEPLG 387 Query: 501 VDGVA--NLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEM 558 + A P+L+ L L RL +A P + L +LNL + C + + L Sbjct: 388 LQSQAFKECPQLELLDLAFTRLHINAPQSPFQNLHFLQVLNL---TYCFLDTSNQHLLAG 444 Query: 559 LP 560 LP Sbjct: 445 LP 446 >4R08-A nrPDB Length = 811 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 14/119 (11%) Query: 440 YADVRVLHLAHKDLTVLC---HLEQLLLVTHLDLSHNRLRALPPA--------LAALRCL 488 + +++VL+L+H ++ L +LE + L S NRL L L+ L Sbjct: 561 FTNLKVLNLSHNNIYTLTDKYNLES-KSLVELVFSGNRLDILWNDDDNRYISIFKGLKNL 619 Query: 489 EVLQASDNALENV--DGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSL 545 L S N L+++ + NLP L N+ + + L PRL LL+L+GN L Sbjct: 620 TRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKL 678 Score = 36.3 bits (82), Expect = 0.037, Method: Composition-based stats. Identities = 47/155 (30%), Positives = 66/155 (42%), Gaps = 18/155 (11%) Query: 407 YFSTLKAVDPMRAAY---LD-DLRSKFLLENSVLKMEYADVRVLHL-AHKDLTVLCHLE- 460 Y T + P AAY LD L S F + + + D+ L+L A+ + VL E Sbjct: 446 YHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFE-NLPDIACLNLSANSNAQVLSGTEF 504 Query: 461 -QLLLVTHLDLSHNRLR-ALPPALAALRCLEVLQASDN--------ALENVDGVANLPRL 510 + V +LDL++NRL AL L LEVL S N +++ + N L Sbjct: 505 SAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNL 564 Query: 511 QELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSL 545 + L L +N + L S LV L GN L Sbjct: 565 KVLNLSHNNIYTLTDKYNLES-KSLVELVFSGNRL 598 Score = 35.9 bits (81), Expect = 0.044, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 6/60 (10%) Query: 462 LLLVTHLDLSHNRLRALPPAL-AALRCLEVLQASDNALENV--DGVANLPRLQELLLCNN 518 L + L L N+L +P L +L L ++Q N + N+ +G++ L L+ L L N Sbjct: 102 LKNLRELLLEDNQLPQIPSGLPESLTELSLIQ---NNIYNITKEGISRLINLKNLYLAWN 158 Score = 35.1 bits (79), Expect = 0.084, Method: Composition-based stats. Identities = 37/124 (29%), Positives = 63/124 (50%), Gaps = 7/124 (5%) Query: 403 ETLQYFSTLKAVDPMRAAYLDDLRSKFLLEN-SVLKMEYADVRVLHLAHKDLTVLCHL-E 460 E +Q F+ LK ++ + + L K+ LE+ S++++ ++ R+ L + D + + Sbjct: 556 EFIQNFTNLKVLN-LSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFK 614 Query: 461 QLLLVTHLDLSHNRLRALPPA--LAALRCLEVLQASDNALE--NVDGVANLPRLQELLLC 516 L +T LDLS NRL+ +P L L L +DN L+ N + PRL+ L L Sbjct: 615 GLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLR 674 Query: 517 NNRL 520 N+L Sbjct: 675 GNKL 678 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 10/78 (12%) Query: 482 LAALRCLEVLQASDNALE-------NVD-GVANLPRLQELLLCNNRLQQ--SAAIQPLVS 531 L L LE+L S N ++ N+ + L L+ L L Q+ QPL+ Sbjct: 311 LTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQ 370 Query: 532 CPRLVLLNLQGNSLCQEE 549 P L +NL N + Q + Sbjct: 371 LPNLSTINLGINFIKQID 388 Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 6/84 (7%) Query: 422 LDDLR-SKFLLENSVLKMEYADVRVLHLAHKDLTVLCH--LEQLLLVTHLDLSHNRLRAL 478 L DLR +K L L + +R L L+H ++ L L ++ + HLDLS N L+ + Sbjct: 670 LLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTI 729 Query: 479 -PPALA--ALRCLEVLQASDNALE 499 AL L +L+ N E Sbjct: 730 NKSALETKTTTKLSMLELHGNPFE 753 >3A7C-A nrPDB Length = 580 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 41/162 (25%), Positives = 70/162 (43%), Gaps = 31/162 (19%) Query: 423 DDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLL----VTHLDLSHNRLRAL 478 ++L + L+NS K + ++ L L+ L + ++LL +T LD+S N + Sbjct: 369 ENLMVEEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPM 428 Query: 479 PPALA-----------------ALRC----LEVLQASDNALENVDGVANLPRLQELLLCN 517 P + C LEVL S+N L++ LPRLQEL + Sbjct: 429 PDSCQWPEKMRFLNLSSTGIRVVKTCIPQTLEVLDVSNNNLDSFSLF--LPRLQELYISR 486 Query: 518 NRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE-EGIQERLAEM 558 N+L+ + P L+++ + N L +GI +RL + Sbjct: 487 NKLKT---LPDASLFPVLLVMKIASNQLKSVPDGIFDRLTSL 525 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 45/125 (36%), Gaps = 22/125 (17%) Query: 444 RVLHLAHKDLTVLCHLEQLL------------------LVTHLDLSHNRLRALPPA---- 481 ++ ++ H DL +L+ L+ + HLDLS N L +L + Sbjct: 63 KITYIGHGDLRACANLQVLILKSSRINTIEGDAFYSLGSLEHLDLSDNHLSSLSSSWFGP 122 Query: 482 LAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQ 541 L++L+ L ++ L NL LQ L + N L L ++ Sbjct: 123 LSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDFAGLTSLNELEIK 182 Query: 542 GNSLC 546 SL Sbjct: 183 ALSLR 187 >5ZSN-B nrPDB Length = 823 Score = 37.4 bits (85), Expect = 0.017, Method: Composition-based stats. Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 11/96 (11%) Query: 459 LEQLLLVTHLDLSHNRLRALPP-ALAALRCLEVLQASDN--------ALENVDGVANLPR 509 + L + +LD S+NRL L A LR LEVL S N ++ NL Sbjct: 516 FQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHMLNFTKNLKV 575 Query: 510 LQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSL 545 LQ+L++ +N + S++ + L L +GN L Sbjct: 576 LQKLMMNDNDI--SSSTSRTMESESLRTLEFRGNHL 609 Score = 32.4 bits (72), Expect = 0.56, Method: Composition-based stats. Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 4/91 (4%) Query: 459 LEQLLLVTHLDLSHNRLRALPPALAAL-RCLEVLQASDNALENVDG--VANLPRLQELLL 515 L L + LDLSHN+L +P L+ R L+ L +N + ++ + + +L+ L L Sbjct: 673 LRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDL 732 Query: 516 CNNRLQQSAAIQ-PLVSCPRLVLLNLQGNSL 545 +N++Q P L +L L N Sbjct: 733 SSNKIQMIQKTSFPENVLNNLKMLLLHHNRF 763 >3A79-B nrPDB Length = 562 Score = 36.7 bits (83), Expect = 0.030, Method: Composition-based stats. Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 2/56 (3%) Query: 465 VTHLDLSHNRLRALPPALAALRCLEVLQASDNALENV-DGV-ANLPRLQELLLCNN 518 V LDL +NR+ ++P + L+ L+ L + N L++V DGV L LQ + L +N Sbjct: 452 VKVLDLHNNRIMSIPKDVTHLQALQELNVASNQLKSVPDGVFDRLTSLQYIWLHDN 507 Score = 35.9 bits (81), Expect = 0.051, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 2/89 (2%) Query: 462 LLLVTHLDLSHNRLRALPPALAAL-RCLEVLQASDNALENVDGVANLPRLQELLLCNNRL 520 L + L LSHNR+R+L + + LE L S N L+N+ + L+ L L N Sbjct: 75 LSELRVLRLSHNRIRSLDFHVFLFNQDLEYLDVSHNRLQNIS-CCPMASLRHLDLSFNDF 133 Query: 521 QQSAAIQPLVSCPRLVLLNLQGNSLCQEE 549 + + +L L L Q + Sbjct: 134 DVLPVCKEFGNLTKLTFLGLSAAKFRQLD 162 >1M9S-A nrPDB Length = 605 Score = 35.1 bits (79), Expect = 0.079, Method: Composition-based stats. Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 34/169 (20%) Query: 410 TLKAVDPMRAAYLDDLRSKFLLEN--------SVLKMEYADVRVLHLAHKDLTVLCHLEQ 461 T+ P++ + DD ++ + +N +V + E + + + D+ + ++ Sbjct: 4 TITVSTPIKQIFPDDAFAETIKDNLKKKSVTDAVTQNELNSIDQIIANNSDIKSVQGIQY 63 Query: 462 LLLVTHLDLSHNRLRALPPALAALRCLEVL----------------------QASDNALE 499 L VT L L+ N+L + P L L+ L L N + Sbjct: 64 LPNVTKLFLNGNKLTDIKP-LTNLKNLGWLFLDENKIKDLSSLKDLKKLKSLSLEHNGIS 122 Query: 500 NVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE 548 +++G+ +LP+L+ L L NN++ I L +L L+L+ N + Sbjct: 123 DINGLVHLPQLESLYLGNNKITD---ITVLSRLTKLDTLSLEDNQISDI 168 >3RG1-A nrPDB Length = 612 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 61/272 (22%), Positives = 106/272 (38%), Gaps = 24/272 (8%) Query: 316 HTFRVIWTGSDSQKECVLL--KDRPECWCRDSATDEQLFRCELSVEK--------STVLQ 365 + F + +S + + L + + SAT E L C++SVE S + Sbjct: 213 NLFIIFKGLQNSTLQSLWLGTFEDTDDQYLTSATFEGL--CDMSVESINLQKHRFSDLSS 270 Query: 366 SELESCKELQELEPENKWC--LLTIILLMRALDPLLYEKETLQYFSTLKAVD--PMRAAY 421 S +QEL+ L + I M +L L+ + + A +R Y Sbjct: 271 STFRCFTRVQELDLTAAHLNGLPSGIEGMNSLKKLVLNANSFDQLCQINAASFPSLRDLY 330 Query: 422 LDDLRSKFLLENSVLKMEYADVRVLHLAHKDLTV--LCHLE--QLLLVTHLDLSHNRLRA 477 + K L L+ + +++ L L+H D+ C+L+ L + +L+LS+N Sbjct: 331 IKGNMRKLDLGTRCLE-KLENLQKLDLSHSDIEASDCCNLQLKNLRHLQYLNLSYNEPLG 389 Query: 478 LPP-ALAALRCLEVLQASDNALENVDGVANLPRLQELLLCN--NRLQQSAAIQPLVSCPR 534 L A LE+L + L + L L + N + L ++ L Sbjct: 390 LEDQAFKECPQLELLDVAFTHLHVKAPHSPFQNLHLLRVLNLSHCLLDTSNQHLLAGLQD 449 Query: 535 LVLLNLQGNSLCQEEGIQERLAEMLPSVSSIL 566 L LNLQGNS + L +M+ S+ ++ Sbjct: 450 LRHLNLQGNSFQDGSISKTNLLQMVGSLEILI 481 >5GY2-A nrPDB Length = 455 Score = 34.0 bits (76), Expect = 0.21, Method: Composition-based stats. Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 11/94 (11%) Query: 459 LEQLLLVTHLDLSHNRLRAL-PPALAALRCLEVLQASDNALENV-DGV-ANLPRLQELLL 515 E L + LDLS+N +RAL + L L+ L N L++V DG+ L LQ++ L Sbjct: 343 FENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQLKSVPDGIFDRLTSLQKIWL 402 Query: 516 CNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEE 549 N SCPR+ L+ N Q+E Sbjct: 403 HTNPWD--------CSCPRIDYLSRWLNKNSQKE 428 >5D3I-A nrPDB Length = 568 Score = 33.2 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 30/148 (20%) Query: 423 DDLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLL----VTHLDLSHNRLRAL 478 ++L + L+NS K + ++ L L+ L + ++LL +T LD+S N + Sbjct: 347 ENLMVEEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPM 406 Query: 479 PPALA-----------------ALRC----LEVLQASDNALENVDGVANLPRLQELLLCN 517 P + C LEVL S+N L++ LPRLQEL + Sbjct: 407 PDSCQWPEKMRFLNLSSTGIRVVKTCIPQTLEVLDVSNNNLDSFSLF--LPRLQELYISR 464 Query: 518 NRLQQSAAIQPLVSCPRLVLLNLQGNSL 545 N+L+ + P L+++ ++ N++ Sbjct: 465 NKLKT---LPDASLFPVLLVMKIRENAV 489 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 45/125 (36%), Gaps = 22/125 (17%) Query: 444 RVLHLAHKDLTVLCHLEQLL------------------LVTHLDLSHNRLRALPPA---- 481 ++ ++ H DL +L+ L+ + HLDLS N L +L + Sbjct: 41 KITYIGHGDLRACANLQVLILKSSRINTIEGDAFYSLGSLEHLDLSDNHLSSLSSSWFGP 100 Query: 482 LAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQ 541 L++L+ L ++ L NL LQ L + N L L ++ Sbjct: 101 LSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDFAGLTSLNELEIK 160 Query: 542 GNSLC 546 SL Sbjct: 161 ALSLR 165 >1XCD-A nrPDB Length = 329 Score = 32.8 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 16/107 (14%) Query: 457 CHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVA--NLPRLQELL 514 CHL + S L +P L L L +N + + NL L L+ Sbjct: 31 CHLRVVQC------SDLGLEKVPKDLPPDTAL--LDLQNNKITEIKDGDFKNLKNLHTLI 82 Query: 515 LCNNRLQQSA--AIQPLVSCPRLVLLNLQGNSLCQE-EGIQERLAEM 558 L NN++ + + A PLV RL L N L + E + + L E+ Sbjct: 83 LINNKISKISPGAFAPLVKLERLY---LSKNQLKELPEKMPKTLQEL 126 >5Y3K-A nrPDB Length = 802 Score = 32.8 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 5/91 (5%) Query: 459 LEQLLLVTHLDLSHNRLRA-LPPALAAL-RCLEVLQASDNALE--NVDGVANLPRLQELL 514 + L + LDLS NRL LP L L + L++L+ +N L N + LP L+ L Sbjct: 603 FQGLRSLIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSSLTLLPNLETLD 662 Query: 515 LCNNRLQQSAAIQPLVSCPRLVLLNLQGNSL 545 L N+L+ + L S +L L++ NS+ Sbjct: 663 LAGNQLKALSN-GSLPSGTQLQRLDVSRNSI 692 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 33/122 (27%), Positives = 42/122 (34%), Gaps = 18/122 (14%) Query: 443 VRVLHLAHKDL-----TVLCHLEQLLLVTHLDLSHNRLRALPPA-------LAALRCLEV 490 +R L LAH + LC + LD S N L + LR L Sbjct: 556 LRYLSLAHNGIHSRVSQQLCS----TSLWALDFSGNSLSQMWAEGDLYLRFFQGLRSLIR 611 Query: 491 LQASDNALENVD--GVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE 548 L S N L + + NLP+ +LL N L P L L+L GN L Sbjct: 612 LDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSSLTLLPNLETLDLAGNQLKAL 671 Query: 549 EG 550 Sbjct: 672 SN 673 >1JL5-A nrPDB Length = 454 Score = 32.4 bits (72), Expect = 0.56, Method: Composition-based stats. Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 17/122 (13%) Query: 446 LHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVA 505 L +++ L L L+ + +D+ +N L+ LP +L E + A +N LE + + Sbjct: 136 LGVSNNQLEKLPELQNSSFLKIIDVDNNSLKKLPDLPPSL---EFIAAGNNQLEELPELQ 192 Query: 506 NLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEM--LPSVS 563 NLP L + NN S +L L L S+ I E L E+ LP ++ Sbjct: 193 NLPFLTAIYADNN------------SLKKLPDLPLSLESIVAGNNILEELPELQNLPFLT 240 Query: 564 SI 565 +I Sbjct: 241 TI 242 >2Z7X-A nrPDB Length = 549 Score = 31.7 bits (70), Expect = 0.84, Method: Composition-based stats. Identities = 39/165 (23%), Positives = 68/165 (41%), Gaps = 30/165 (18%) Query: 421 YLD---DLRSKFLLENSVLKMEYADVRVLHLAHKDLTVLCHLEQLLL----VTHLDLSHN 473 YLD +L + L+NS + + ++ L L L L + LL +T++D+S N Sbjct: 338 YLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKN 397 Query: 474 RLRALPPALAALRCLEVLQASDNALENVDGV-------------------ANLPRLQELL 514 ++P ++ L S + +V G NLP+L+EL Sbjct: 398 SFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLKELY 457 Query: 515 LCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE-EGIQERLAEM 558 + N+L + P L++L + N L +GI +RL + Sbjct: 458 ISRNKLMT---LPDASLLPMLLVLKISRNQLKSVPDGIFDRLTSL 499 >4WSS-A nrPDB Length = 514 Score = 31.7 bits (70), Expect = 0.90, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 29/74 (39%), Gaps = 5/74 (6%) Query: 43 ELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRV 102 E +++ F +W E+L LE E++ + A VK ++S LR Sbjct: 401 EFSNLEKRISNLNKRMEDGFLDVWTYNAELLVLLENERTLDMHDANVKNLHEKVKSQLRD 460 Query: 103 NPKS-----YGTWH 111 N K + WH Sbjct: 461 NAKDLGNGCFEFWH 474 >4ECN-A nrPDB Length = 876 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 45/110 (40%), Gaps = 11/110 (10%) Query: 458 HLEQLLLVTHLDLSHNRLRALPPALAA--LRCLEVLQASDNALENVDGVA-NLPRLQELL 514 + + L+T +DL N+L +L A L L + S N + N +L+ Sbjct: 723 NYKNTYLLTTIDLRFNKLTSLSDDFRATTLPYLSNMDVSYNCFSSFPTQPLNSSQLKAFG 782 Query: 515 LCNNRLQQSAAI-----QPLVSCPRLVLLNLQGNSLCQEEGIQERLAEML 559 + + R + I + +CP L+ L + N + + + E+L L Sbjct: 783 IRHQRDAEGNRILRQWPTGITTCPSLIQLQIGSNDIRKVD---EKLTPQL 829 >4WYK-A nrPDB Length = 461 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 1/50 (2%) Query: 505 ANLPRLQELLLCNNRLQQSAAIQPLVS-CPRLVLLNLQGNSLCQEEGIQE 553 N+P L L L NNRL + + +V P L +LNL GN L E + + Sbjct: 168 ENIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDK 217 >3NTV-A nrPDB Length = 232 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 65/150 (43%), Gaps = 28/150 (18%) Query: 418 RAAYLDDLRSKFLL-----ENSVLKM--EYADVRVLHLAHKDLTVLCHLEQLLLVTHLDL 470 R +++DDL K+L+ +NS +++ E+A+V + + D L ++QL+ Sbjct: 17 RGSHMDDLNKKYLIDLHQHQNSSIEVLREFAEVNEVPIV--DRLTLDLIKQLI------- 67 Query: 471 SHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLV 530 R+ + L + ++ + V + R N + Q A Q L Sbjct: 68 ---RMNNVKNILEIGTAIGYSSMQFASISDDIHVTTIER-------NETMIQYAK-QNLA 116 Query: 531 SCP-RLVLLNLQGNSLCQEEGIQERLAEML 559 + + ++GN+L Q E + +++ +M+ Sbjct: 117 TYHFENQVRIIEGNALEQFENVNDKVYDMI 146 >1HXR-A nrPDB Length = 115 Score = 30.5 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 22/57 (38%), Gaps = 4/57 (7%) Query: 252 REEACLSVCFSRPLTVG----SRMGTLLLMVDEAPLSVEWRTPDGRNRPSHVWLCDL 304 R+ C SR L G SR L + + P V+ PDG H + D+ Sbjct: 10 RKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPDLVDGSNPDGDVLEEHWLVNDM 66 >4QDH-A nrPDB Length = 438 Score = 30.5 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 3/62 (4%) Query: 491 LQASDNALENV-DGV-ANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQE 548 L+ N L+++ GV L +L +L L N L + + V+ RL L+L NS+ Q Sbjct: 40 LELESNKLQSLPHGVFDKLTQLTKLSLSRNNLV-TIKPEMFVNLSRLQCLSLSHNSIAQA 98 Query: 549 EG 550 Sbjct: 99 VN 100 >1KOH-A nrPDB Length = 277 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 1/50 (2%) Query: 505 ANLPRLQELLLCNNRLQQSAAIQPLVS-CPRLVLLNLQGNSLCQEEGIQE 553 N+P L L L NNRL + + +V P L +LNL GN L E + + Sbjct: 167 ENIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDK 216 >5J5V-A nrPDB Length = 323 Score = 30.1 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 24/64 (37%), Gaps = 7/64 (10%) Query: 64 TLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRLPEP 123 T+ RR++L+ L E A +K + E + NP+ Y LL + P Sbjct: 95 TMSIERRKLLKALGANLVLTEGAKGMKGAIQKAEEIVASNPEKY-------LLLQQFSNP 147 Query: 124 NWAR 127 Sbjct: 148 ANPE 151 >4AIB-A nrPDB Length = 395 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 23/56 (41%) Query: 331 CVLLKDRPECWCRDSATDEQLFRCELSVEKSTVLQSELESCKELQELEPENKWCLL 386 C+ + + C C +E E + + S+ + +EL E+EP W L Sbjct: 302 CIWFEKQKSCECITQKVNENTKMYESIIYGPSCNGSDKVATQELPEMEPGKDWLLF 357 >5CLR-A nrPDB Length = 451 Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 45/111 (40%), Gaps = 9/111 (8%) Query: 178 YSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLG 237 +SW S L P+L+ Q D ++ + L L + F P Q + + +G Sbjct: 231 PASWGTASYLAPELNAQEDFIAFSQVSD---LFALAYSLDELFN-PFRQV--KFAKVDIG 284 Query: 238 RAEPHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWR 288 H VL + EAC++ S +V + + +L + P S + R Sbjct: 285 IKNKHLVLLHAEI---EACITGLMSNETSVRTLYFSRILQLQRVPESFKSR 332 >3WPI-A nrPDB Length = 803 Score = 29.3 bits (64), Expect = 4.8, Method: Composition-based stats. Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 13/109 (11%) Query: 446 LHLAHKDLTVL--CHLEQLLLVTHLDLSHN---------RLRALPPALAALRCLEVLQAS 494 L L+H ++ VL L L + L + N ++ P AL L L L Sbjct: 127 LSLSHTNILVLDANSLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSQLTHLSLK 186 Query: 495 DNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGN 543 N L V LP E LL + L + L L +L++ GN Sbjct: 187 YNNLTKVP--RQLPPSLEYLLVSYNLIVKLGPEDLAQLTSLRVLDVGGN 233 >5AJ4-Ba nrPDB Length = 423 Score = 29.0 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 23/63 (36%), Gaps = 8/63 (12%) Query: 109 TWHHRCWLLSRLPEPNWARELELCARF------LEADERNFHCWDYRRFV--AAQAAVAP 160 +H RC LL + + W + +L L D RN R + + A + Sbjct: 106 VFHQRCRLLEGVKQALWLTKTQLIEGLPEKVLRLADDPRNHIENQDERVLNAISHARLWH 165 Query: 161 AEE 163 + E Sbjct: 166 STE 168 >3LY6-A nrPDB Length = 697 Score = 29.0 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 22/62 (35%), Gaps = 2/62 (3%) Query: 64 TLWNCRREVLQHLETEKSPEESAALVKAELGFLESCLR-VNPKSYGTWHHRCWLLSRLPE 122 T+ C + + S + + + E F KS W+ CW+ S + Sbjct: 286 TVLRCLGIPTRVVTNYNSAHDQNSNLLIEY-FRNEFGEIQGDKSEMIWNFHCWVESWMTR 344 Query: 123 PN 124 P+ Sbjct: 345 PD 346 >2R91-A nrPDB Length = 286 Score = 29.0 bits (63), Expect = 6.7, Method: Composition-based stats. Identities = 18/105 (17%), Positives = 37/105 (35%), Gaps = 6/105 (5%) Query: 117 LSRLPEPNWARELELCARFLEADERNFHCWDYRRFVAAQAAVAPAEELAFTDSLITRNFS 176 + R + A+EL + +E H Y+R++ ++ L F + + Sbjct: 134 VGRDVDARAAKELGCIRGVKDTNESLAHTLAYKRYLPQARVYNGSDSLVFASFAVRLDGV 193 Query: 177 NYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFT 221 SS +Y LL + +G R + L+ + + Sbjct: 194 VASSANYLPELLAGIRDAVAAGDIERA------RSLQFLLDEIVE 232 >5OOM-5 nrPDB Length = 423 Score = 28.6 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 17/41 (41%), Gaps = 6/41 (14%) Query: 109 TWHHRCWLLSRLPEPNWARELELCARF------LEADERNF 143 +HHRC LL + + W + +L L D RN Sbjct: 106 IFHHRCRLLEGVKQALWLTKTKLIEGLPEKVLSLVDDPRNH 146 >5UJB-A nrPDB Length = 609 Score = 28.2 bits (61), Expect = 9.2, Method: Composition-based stats. Identities = 38/220 (17%), Positives = 65/220 (29%), Gaps = 11/220 (5%) Query: 166 FTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPND 225 F D L T + C Q + + Q + L + + + T +D Sbjct: 94 FGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHD 153 Query: 226 QSAWFYHRWLLGRAEPHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSV 285 F ++L A H + F+ + LL +DE Sbjct: 154 NEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEG 213 Query: 286 EWRTPDGRNRPSHV------WLCDLPAASLNDQLPQHTF-RVIWTGSDSQKECVLLKDRP 338 + + R + + + A L+ + P+ F V +D K Sbjct: 214 KASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGD 273 Query: 339 ECWCRDSATDEQLFRCELSVEKSTVLQSELESCKELQELE 378 C D D + C E + S+L+ C E LE Sbjct: 274 LLECADDRADLAKYIC----ENQDSISSKLKECCEKPLLE 309 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.126 0.342 Lambda K H 0.267 0.0384 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,027,091 Number of Sequences: 36641 Number of extensions: 742045 Number of successful extensions: 2306 Number of sequences better than 10.0: 58 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 63 Number of HSP's that attempted gapping in prelim test: 1947 Number of HSP's gapped (non-prelim): 204 length of query: 567 length of database: 10,336,785 effective HSP length: 102 effective length of query: 465 effective length of database: 6,599,403 effective search space: 3068722395 effective search space used: 3068722395 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 61 (28.2 bits)