BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q08209 (521 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4ORB-A nrPDB 1059 0.0 4IL1-A nrPDB 1014 0.0 4ORC-A nrPDB 915 0.0 5W0W-C nrPDB 227 1e-59 3V4Y-A nrPDB 224 6e-59 1S70-A nrPDB 221 5e-58 4ZVZ-A nrPDB 216 2e-56 5JJT-A nrPDB 215 4e-56 4JA9-A nrPDB 212 3e-55 5JPE-A nrPDB 204 7e-53 3ICF-A nrPDB 195 4e-50 2F2P-A nrPDB 48 1e-05 2LHI-A nrPDB 39 0.005 1G5B-A nrPDB 38 0.012 5VJW-A nrPDB 35 0.11 5W2J-A nrPDB 33 0.30 3SS3-A nrPDB 33 0.30 5UQE-A nrPDB 33 0.32 5WJ6-A nrPDB 33 0.38 5JYO-D nrPDB 32 0.46 1YQX-A nrPDB 29 4.1 5IJZ-A nrPDB 28 9.2 >4ORB-A nrPDB Length = 519 Score = 1059 bits (2739), Expect = 0.0, Method: Compositional matrix adjust. Identities = 509/521 (97%), Positives = 510/521 (97%), Gaps = 10/521 (1%) Query: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV Sbjct: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60 Query: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV Sbjct: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120 Query: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD Sbjct: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180 Query: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG Sbjct: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240 Query: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300 NEKTQEHFTHNTVRGCSYFYSYPAVC+FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP Sbjct: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300 Query: 301 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK 360 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK Sbjct: 301 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK 360 Query: 361 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 420 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV Sbjct: 361 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 420 Query: 421 LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN 480 LTLKGLTPTGMLPSGVLSGGKQTLQS AIKGFSPQHKITSFEEAKGLDRIN Sbjct: 421 LTLKGLTPTGMLPSGVLSGGKQTLQS----------AIKGFSPQHKITSFEEAKGLDRIN 470 Query: 481 ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ 521 ERMPPRRDAMPSDANLNSINKAL SETNGTDSNGSNSSNIQ Sbjct: 471 ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ 511 >4IL1-A nrPDB Length = 823 Score = 1014 bits (2622), Expect = 0.0, Method: Compositional matrix adjust. Identities = 481/492 (97%), Positives = 482/492 (97%), Gaps = 10/492 (2%) Query: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV Sbjct: 334 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 393 Query: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV Sbjct: 394 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 453 Query: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD Sbjct: 454 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 513 Query: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG Sbjct: 514 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 573 Query: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300 NEKTQEHFTHNTVRGCSYFYSYPAVC+FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP Sbjct: 574 NEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 633 Query: 301 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK 360 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK Sbjct: 634 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK 693 Query: 361 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 420 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV Sbjct: 694 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 753 Query: 421 LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN 480 LTLKGLTPTGMLPSGVLSGGKQTLQS AIKGFSPQHKITSFEEAKGLDRIN Sbjct: 754 LTLKGLTPTGMLPSGVLSGGKQTLQS----------AIKGFSPQHKITSFEEAKGLDRIN 803 Query: 481 ERMPPRRDAMPS 492 ERMPPRRDAMPS Sbjct: 804 ERMPPRRDAMPS 815 >4ORC-A nrPDB Length = 544 Score = 915 bits (2364), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/501 (85%), Positives = 474/501 (94%), Gaps = 3/501 (0%) Query: 14 TDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILR 73 DRVVKAVPFPP+HRLT++EVFD DG PRVD+LK HL+KEGR++E +ALRII EGA+ILR Sbjct: 43 ADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILR 102 Query: 74 QEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYL 133 +EK +++++AP+TVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYL Sbjct: 103 REKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYL 162 Query: 134 WALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQ 193 W LKILYP TLFLLRGNHECRHLTEYFTFKQECKIKYSERVY+ACM+AFD LPLAAL+NQ Sbjct: 163 WVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQ 222 Query: 194 QFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTV 253 QFLCVHGGLSPEI+TLDDIR+LDRFKEPPA+GPMCD+LWSDP EDFGNEK+QEHF+HNTV Sbjct: 223 QFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTV 282 Query: 254 RGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLD 313 RGCSYFY+YPAVCEFLQ+NNLLSI+RAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLD Sbjct: 283 RGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLD 342 Query: 314 VYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICS 373 VYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVL+ICS Sbjct: 343 VYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICS 402 Query: 374 DDELGSE-EDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGML 432 DDEL +E ED FDG +AAARKE+IRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGML Sbjct: 403 DDELMTEGEDQFDG-SAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGML 461 Query: 433 PSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAMPS 492 PSGVL+GG+QTLQSATVEAIEA++AI+GFSP H+I SFEEAKGLDRINERMPPR+DA+ Sbjct: 462 PSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQ 521 Query: 493 DANLNSINKALTSETNGTDSN 513 D NS+N A +E +GT ++ Sbjct: 522 DG-FNSLNTAHATENHGTGNH 541 >5W0W-C nrPDB Length = 311 Score = 227 bits (578), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 123/286 (43%), Positives = 169/286 (59%), Gaps = 16/286 (5%) Query: 55 RLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYL 114 +L ES + + IL +E N+ ++ PVTVCGD+HGQF DLM+LF +GG +T YL Sbjct: 24 QLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 83 Query: 115 FLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSE-R 173 F+GDYVDRGY+S+E V L ALK+ Y + + +LRGNHE R +T+ + F EC KY Sbjct: 84 FMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNAN 143 Query: 174 VYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWS 233 V+ D FD LPL AL++ Q C+HGGLSP I+TLD IR LDR +E P GPMCD+LWS Sbjct: 144 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 203 Query: 234 DPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRK 293 DP +D G + RG Y + F N L + RAH+ GY Sbjct: 204 DP-DDRGGWGI-------SPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHD 255 Query: 294 SQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV-MNIRQFNCSP 338 +++TIFSAPNY N+AA+++ ++ + + QF+ +P Sbjct: 256 R------NVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP 295 >3V4Y-A nrPDB Length = 306 Score = 224 bits (572), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 110/278 (39%), Positives = 171/278 (61%), Gaps = 13/278 (4%) Query: 52 KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANT 111 K +L E+ + + I + LL+++AP+ +CGDIHGQ++DL++LFE GG P + Sbjct: 25 KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 84 Query: 112 RYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYS 171 YLFLGDYVDRG S+E + L A KI YP+ FLLRGNHEC + + F ECK +Y+ Sbjct: 85 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 144 Query: 172 ERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDIL 231 +++ D F+CLP+AA+++++ C HGGLSP++ +++ IR++ R + P G +CD+L Sbjct: 145 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 204 Query: 232 WSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMY 291 WSDP +K + + N RG S+ + V +FL ++L I RAH+ + GY + Sbjct: 205 WSDP------DKDVQGWGEND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFF 257 Query: 292 RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329 K Q L+T+FSAPNY ++N A++ + +M Sbjct: 258 AKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM 289 >1S70-A nrPDB Length = 330 Score = 221 bits (564), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 113/300 (37%), Positives = 176/300 (58%), Gaps = 21/300 (7%) Query: 38 DGKPRVDILKAHLM--------KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCG 89 DG+ VD L L+ K ++ E+ + + I + LL+++AP+ +CG Sbjct: 6 DGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICG 65 Query: 90 DIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149 DIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E + L A KI YP+ FLLRG Sbjct: 66 DIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRG 125 Query: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTL 209 NHEC + + F ECK +++ +++ D F+CLP+AA+++++ C HGGLSP++ ++ Sbjct: 126 NHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSM 185 Query: 210 DDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFL 269 + IR++ R + P G +CD+LWSDP +K + + N RG S+ + V +FL Sbjct: 186 EQIRRIMRPTDVPDTGLLCDLLWSDP------DKDVQGWGEND-RGVSFTFGADVVSKFL 238 Query: 270 QHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329 ++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++ + +M Sbjct: 239 NRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSVDETLM 292 >4ZVZ-A nrPDB Length = 333 Score = 216 bits (550), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 120/315 (38%), Positives = 179/315 (56%), Gaps = 27/315 (8%) Query: 38 DGKPRVDILKAHLMK----EGRLEESVALRIITEGASILRQEKNLLDID----APVTVCG 89 DGK + +K LM+ + +L A +I+ + +L + L++ +TVCG Sbjct: 17 DGKVTISFMK-ELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCG 75 Query: 90 DIHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLR 148 D HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLR Sbjct: 76 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 135 Query: 149 GNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIN- 207 GNHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL E Sbjct: 136 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 195 Query: 208 TLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCE 267 TLDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + Sbjct: 196 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISK--------RGVSCQFGPDVTKA 247 Query: 268 FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 327 FL+ NNL I+R+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 248 FLEENNLDYIIRSHEVKAEGYEVAHGGRC------VTVFSAPNYCDQMGNKASYIHLQGS 301 Query: 328 VM--NIRQFNCSPHP 340 + QF PHP Sbjct: 302 DLRPQFHQFTAVPHP 316 >5JJT-A nrPDB Length = 479 Score = 215 bits (547), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 123/308 (39%), Positives = 175/308 (56%), Gaps = 27/308 (8%) Query: 56 LEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDLMKLFEVGGSPANT 111 L + A +I+ + IL +L+DI P +TVCGD+HGQF+DL+ +FE+ G P+ Sbjct: 186 LHKRYAYQIVLQTRQILLALPSLVDISVPHGKHITVCGDVHGQFYDLLNIFELNGLPSEE 245 Query: 112 R-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY 170 YLF GD+VDRG FS+E +L L+A K + P +++L RGNHE + + + + F+ E + K Sbjct: 246 NPYLFNGDFVDRGSFSVEIILTLFAFKCMCPSSIYLARGNHESKSMNKIYGFEGEVRSKL 305 Query: 171 SERVYDACMDAFDCLPLAALMNQQFLCVHGGL-SPEINTLDDIRKLDRFKEPPAYGPMCD 229 SE+ D + F LPLA ++N + VHGGL S + L DIR +DRF EPP G MC+ Sbjct: 306 SEKFVDLFAEVFCYLPLAHVINGKVFVVHGGLFSVDGVKLSDIRAIDRFCEPPEEGLMCE 365 Query: 230 ILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYR 289 +LWSDP G ++ RG + FLQ NNL ++R+HE +D GY Sbjct: 366 LLWSDPQPLPGRGPSK--------RGVGLSFGGDVTKRFLQDNNLDLLVRSHEVKDEGYE 417 Query: 290 MYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM--NIRQFNCSPHPYWLP--- 344 + + LIT+FSAPNY D NK A +++E M NI F+ PHP P Sbjct: 418 VEHDGK------LITVFSAPNYCDQMGNKGAFIRFEAPDMKPNIVTFSAVPHPDVKPMAY 471 Query: 345 --NFMDVF 350 NF+ +F Sbjct: 472 ANNFLRMF 479 >4JA9-A nrPDB Length = 488 Score = 212 bits (540), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 120/319 (37%), Positives = 179/319 (56%), Gaps = 27/319 (8%) Query: 38 DGKPRVDILKAHLMK----EGRLEESVALRIITEGASILRQEKNLLDID----APVTVCG 89 DGK + +K LM+ + +L A +I+ + +L + L++ +TVCG Sbjct: 172 DGKVTITFMK-DLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCG 230 Query: 90 DIHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLR 148 D HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLR Sbjct: 231 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 290 Query: 149 GNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIN- 207 GNHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL E Sbjct: 291 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 350 Query: 208 TLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCE 267 TLDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + Sbjct: 351 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSK--------RGVSCQFGPDVTKA 402 Query: 268 FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 327 FL+ N L I+R+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 403 FLEENQLDYIIRSHEVKAEGYEVAHGGRC------VTVFSAPNYCDQMGNKASYIHLQGS 456 Query: 328 VM--NIRQFNCSPHPYWLP 344 + QF PHP P Sbjct: 457 DLRPQFHQFTAVPHPNVKP 475 >5JPE-A nrPDB Length = 311 Score = 204 bits (519), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 106/282 (37%), Positives = 162/282 (57%), Gaps = 19/282 (6%) Query: 54 GRLEESVALR------IITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGS 107 G+ ++V L+ I I + +LL++ PV V GD+HGQ+ DL+++F G Sbjct: 20 GKRTKNVCLKNTEIELICASAREIFLSQPSLLELAPPVKVVGDVHGQYHDLIRIFSKCGF 79 Query: 108 PANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECK 167 P T YLFLGDYV+RG S+E +L L KI YP+ FLLRGNHEC ++T + F ECK Sbjct: 80 PPKTNYLFLGDYVNRGKQSLETILLLLCYKIKYPENFFLLRGNHECANVTRVYGFYDECK 139 Query: 168 IKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPM 227 + + + + +D F+ LP+AA++ + CVHGGLSP +N++D+IR + R + P +G + Sbjct: 140 RRCNIKTWKLFIDTFNTLPIAAIVAGKIFCVHGGLSPVLNSMDEIRNIARPTDVPDFGLL 199 Query: 228 CDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAG 287 D+LWSDP + + E RG SY +S A+ +FL N + RAH + G Sbjct: 200 NDLLWSDPADTINEWEDNE-------RGVSYVFSKVAINKFLSKFNFDLVCRAHMVVEDG 252 Query: 288 YRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329 Y + +L+T+FSAPNY ++N AV+ +++ Sbjct: 253 YEFFNDR------TLVTVFSAPNYCGEFDNWGAVMGVSEDLL 288 >3ICF-A nrPDB Length = 335 Score = 195 bits (496), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 106/282 (37%), Positives = 159/282 (56%), Gaps = 24/282 (8%) Query: 50 LMKEGRLEESVALRIITEGASILRQEKNLLDI------DAPVTVCGDIHGQFFDLMKLFE 103 +K L + II+ ++ RQE +++++ D ++VCGD HGQF+D++ LF Sbjct: 25 FLKGKYLPKKYVAAIISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFR 84 Query: 104 VGG--SPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFT 161 G P +T YLF GD+VDRG +S E L + LKIL+P FL RGNHE ++ + + Sbjct: 85 KFGKVGPKHT-YLFNGDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYG 143 Query: 162 FKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGL-SPEINTLDDIRKLDRFKE 220 F+ ECK KYS+R+++ +F+ LPLA L+N +L +HGGL S TL D + +DRF + Sbjct: 144 FEDECKYKYSQRIFNMFAQSFESLPLATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQ 203 Query: 221 PPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRA 280 PP G ++LW+DP E G +Q RG + + FL++N L I R+ Sbjct: 204 PPRDGAFMELLWADPQEANGMGPSQ--------RGLGHAFGPDITDRFLRNNKLRKIFRS 255 Query: 281 HEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVL 322 HE + G + +K + L+T+FSAPNY D N V+ Sbjct: 256 HELRMGGVQFEQKGK------LMTVFSAPNYCDSQGNLGGVI 291 >2F2P-A nrPDB Length = 179 Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 22/22 (100%), Positives = 22/22 (100%) Query: 392 RKEVIRNKIRAIGKMARVFSVL 413 RKEVIRNKIRAIGKMARVFSVL Sbjct: 158 RKEVIRNKIRAIGKMARVFSVL 179 >2LHI-A nrPDB Length = 176 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 27/70 (38%), Positives = 40/70 (57%), Gaps = 12/70 (17%) Query: 354 LPFVGEKVTEMLVN-VLNICSDDELGSEEDGFD--------GATAAARKEVIRNKIRAIG 404 L +GEK+T+ V+ +L SD GS E G++ R++ +RNKI AI Sbjct: 110 LTSIGEKLTDAEVDDMLREVSD---GSGEINIQQFAALLSKGSSTGTRRKALRNKILAIA 166 Query: 405 KMARVFSVLR 414 K++R+FSVLR Sbjct: 167 KVSRMFSVLR 176 >1G5B-A nrPDB Length = 221 Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust. Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 7/69 (10%) Query: 85 VTVCGDIHGQFFDLM-KLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKT 143 + V GD+HG + +LM KL +G + +GD VDRG ++EC L+++ Sbjct: 15 IWVVGDLHGCYTNLMNKLDTIGFDNKKDLLISVGDLVDRGAENVEC------LELITFPW 68 Query: 144 LFLLRGNHE 152 +RGNHE Sbjct: 69 FRAVRGNHE 77 >5VJW-A nrPDB Length = 309 Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 7/75 (9%) Query: 85 VTVCGDIHGQFFDLMKLF---EVGGSPAN---TRYLFLGDYVDRGYFSIECVLYLWALKI 138 V GDIHG L L+ + P++ +FLGDY DRG + + + +L +L Sbjct: 8 VICVGDIHGYISKLNNLWLNLQSAIDPSDFSSALVIFLGDYCDRGPETRKVIDFLISLPE 67 Query: 139 LYP-KTLFLLRGNHE 152 +P +T L GNH+ Sbjct: 68 KHPDQTHVFLAGNHD 82 >5W2J-A nrPDB Length = 411 Score = 33.1 bits (74), Expect = 0.30, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 4/42 (9%) Query: 221 PPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSY 262 P G MC WS PL+ GN HF H+ V C+ F++Y Sbjct: 358 PNVMGMMC---WSPPLDKMGNSVKGIHFCHDLVSLCN-FHNY 395 >3SS3-A nrPDB Length = 479 Score = 33.1 bits (74), Expect = 0.30, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 4/48 (8%) Query: 221 PPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEF 268 P G MC WS PL+ GN HF H+ V C+ F++Y + F Sbjct: 374 PNVMGMMC---WSPPLDKMGNSVKGIHFCHDLVSLCN-FHNYDNLRHF 417 >5UQE-A nrPDB Length = 520 Score = 33.1 bits (74), Expect = 0.32, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 4/48 (8%) Query: 221 PPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEF 268 P G MC WS PL+ GN HF H+ V C+ F++Y + F Sbjct: 357 PNVMGMMC---WSPPLDKMGNSVKGIHFCHDLVSLCN-FHNYDNLRHF 400 >5WJ6-A nrPDB Length = 539 Score = 32.7 bits (73), Expect = 0.38, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 4/48 (8%) Query: 221 PPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEF 268 P G MC WS PL+ GN HF H+ V C+ F++Y + F Sbjct: 434 PNVMGMMC---WSPPLDKMGNSVKGIHFCHDLVSLCN-FHNYDNLRHF 477 >5JYO-D nrPDB Length = 333 Score = 32.3 bits (72), Expect = 0.46, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 4/42 (9%) Query: 221 PPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSY 262 P G MC WS PL+ GN HF H+ V C+ F++Y Sbjct: 293 PNVMGMMC---WSPPLDKMGNSVKGIHFCHDLVSLCN-FHNY 330 >1YQX-A nrPDB Length = 366 Score = 29.3 bits (64), Expect = 4.1, Method: Compositional matrix adjust. Identities = 20/96 (20%), Positives = 44/96 (45%), Gaps = 1/96 (1%) Query: 388 TAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSA 447 AA + I + + A+ + +F +L+ + +L P LP+ L G++ + + Sbjct: 247 AAAGTLDGIIDTVSAVHPLLPLFGLLKSHGKLILVGAPEKPL-ELPAFSLIAGRKIVAGS 305 Query: 448 TVEAIEADEAIKGFSPQHKITSFEEAKGLDRINERM 483 + ++ + + F+ +H IT+ E D +N M Sbjct: 306 GIGGMKETQEMIDFAAKHNITADIEVISTDYLNTAM 341 >5IJZ-A nrPDB Length = 447 Score = 28.1 bits (61), Expect = 9.2, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 24/47 (51%), Gaps = 2/47 (4%) Query: 351 TWSLPFVGEKVTEMLVNVLNICSDD--ELGSEEDGFDGATAAARKEV 395 +WS + E++ ++ N+ C++ E G E D GA A K+V Sbjct: 391 SWSFEYTDERLQVIMKNIFKTCAETAAEYGHENDYVVGANIAGFKKV 437 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4ORB-A nrPDB 938 0.0 4ORC-A nrPDB 885 0.0 4IL1-A nrPDB 883 0.0 1S70-A nrPDB 445 e-125 3V4Y-A nrPDB 444 e-125 4ZVZ-A nrPDB 419 e-117 5JJT-A nrPDB 415 e-116 4JA9-A nrPDB 414 e-116 5W0W-C nrPDB 409 e-114 5JPE-A nrPDB 408 e-114 3ICF-A nrPDB 378 e-105 2F2P-A nrPDB 48 1e-05 Sequences not found previously or not previously below threshold: 1V73-A nrPDB 51 1e-06 1G5B-A nrPDB 48 1e-05 2DFJ-A nrPDB 42 7e-04 5VJW-A nrPDB 42 0.001 2LHI-A nrPDB 41 0.001 6DJW-A nrPDB 32 0.47 4CKE-A nrPDB 32 0.51 1YQX-A nrPDB 32 0.59 6CV7-A nrPDB 32 0.79 1KAN-A nrPDB 32 0.95 3WF0-A nrPDB 31 1.1 5T4M-A nrPDB 31 1.2 2FAH-A nrPDB 31 1.5 2CV2-A nrPDB 31 1.6 5ULY-A nrPDB 31 1.7 4AZV-A nrPDB 29 4.3 >4ORB-A nrPDB Length = 519 Score = 938 bits (2425), Expect = 0.0, Method: Composition-based stats. Identities = 509/521 (97%), Positives = 510/521 (97%), Gaps = 10/521 (1%) Query: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV Sbjct: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60 Query: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV Sbjct: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120 Query: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD Sbjct: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180 Query: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG Sbjct: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240 Query: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300 NEKTQEHFTHNTVRGCSYFYSYPAVC+FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP Sbjct: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300 Query: 301 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK 360 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK Sbjct: 301 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK 360 Query: 361 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 420 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV Sbjct: 361 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 420 Query: 421 LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN 480 LTLKGLTPTGMLPSGVLSGGKQTLQS AIKGFSPQHKITSFEEAKGLDRIN Sbjct: 421 LTLKGLTPTGMLPSGVLSGGKQTLQS----------AIKGFSPQHKITSFEEAKGLDRIN 470 Query: 481 ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ 521 ERMPPRRDAMPSDANLNSINKAL SETNGTDSNGSNSSNIQ Sbjct: 471 ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ 511 >4ORC-A nrPDB Length = 544 Score = 885 bits (2286), Expect = 0.0, Method: Composition-based stats. Identities = 429/501 (85%), Positives = 474/501 (94%), Gaps = 3/501 (0%) Query: 14 TDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILR 73 DRVVKAVPFPP+HRLT++EVFD DG PRVD+LK HL+KEGR++E +ALRII EGA+ILR Sbjct: 43 ADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILR 102 Query: 74 QEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYL 133 +EK +++++AP+TVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYL Sbjct: 103 REKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYL 162 Query: 134 WALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQ 193 W LKILYP TLFLLRGNHECRHLTEYFTFKQECKIKYSERVY+ACM+AFD LPLAAL+NQ Sbjct: 163 WVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQ 222 Query: 194 QFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTV 253 QFLCVHGGLSPEI+TLDDIR+LDRFKEPPA+GPMCD+LWSDP EDFGNEK+QEHF+HNTV Sbjct: 223 QFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTV 282 Query: 254 RGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLD 313 RGCSYFY+YPAVCEFLQ+NNLLSI+RAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLD Sbjct: 283 RGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLD 342 Query: 314 VYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICS 373 VYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVL+ICS Sbjct: 343 VYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICS 402 Query: 374 DDELGSE-EDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGML 432 DDEL +E ED FDG +AAARKE+IRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGML Sbjct: 403 DDELMTEGEDQFDG-SAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGML 461 Query: 433 PSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAMPS 492 PSGVL+GG+QTLQSATVEAIEA++AI+GFSP H+I SFEEAKGLDRINERMPPR+DA+ Sbjct: 462 PSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQ 521 Query: 493 DANLNSINKALTSETNGTDSN 513 D NS+N A +E +GT ++ Sbjct: 522 DG-FNSLNTAHATENHGTGNH 541 >4IL1-A nrPDB Length = 823 Score = 883 bits (2281), Expect = 0.0, Method: Composition-based stats. Identities = 481/492 (97%), Positives = 482/492 (97%), Gaps = 10/492 (2%) Query: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV Sbjct: 334 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 393 Query: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV Sbjct: 394 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 453 Query: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD Sbjct: 454 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 513 Query: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG Sbjct: 514 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 573 Query: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300 NEKTQEHFTHNTVRGCSYFYSYPAVC+FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP Sbjct: 574 NEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 633 Query: 301 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK 360 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK Sbjct: 634 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK 693 Query: 361 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 420 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV Sbjct: 694 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 753 Query: 421 LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN 480 LTLKGLTPTGMLPSGVLSGGKQTLQS AIKGFSPQHKITSFEEAKGLDRIN Sbjct: 754 LTLKGLTPTGMLPSGVLSGGKQTLQS----------AIKGFSPQHKITSFEEAKGLDRIN 803 Query: 481 ERMPPRRDAMPS 492 ERMPPRRDAMPS Sbjct: 804 ERMPPRRDAMPS 815 >1S70-A nrPDB Length = 330 Score = 445 bits (1144), Expect = e-125, Method: Composition-based stats. Identities = 113/300 (37%), Positives = 176/300 (58%), Gaps = 21/300 (7%) Query: 38 DGKPRVDILKAHLM--------KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCG 89 DG+ VD L L+ K ++ E+ + + I + LL+++AP+ +CG Sbjct: 6 DGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICG 65 Query: 90 DIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149 DIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E + L A KI YP+ FLLRG Sbjct: 66 DIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRG 125 Query: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTL 209 NHEC + + F ECK +++ +++ D F+CLP+AA+++++ C HGGLSP++ ++ Sbjct: 126 NHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSM 185 Query: 210 DDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFL 269 + IR++ R + P G +CD+LWSDP +K + + N RG S+ + V +FL Sbjct: 186 EQIRRIMRPTDVPDTGLLCDLLWSDP------DKDVQGWGEND-RGVSFTFGADVVSKFL 238 Query: 270 QHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329 ++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++ + +M Sbjct: 239 NRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSVDETLM 292 >3V4Y-A nrPDB Length = 306 Score = 444 bits (1142), Expect = e-125, Method: Composition-based stats. Identities = 113/299 (37%), Positives = 177/299 (59%), Gaps = 21/299 (7%) Query: 39 GKPRVDILKAHLM--------KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGD 90 G +D + L+ K +L E+ + + I + LL+++AP+ +CGD Sbjct: 4 GSLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGD 63 Query: 91 IHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGN 150 IHGQ++DL++LFE GG P + YLFLGDYVDRG S+E + L A KI YP+ FLLRGN Sbjct: 64 IHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGN 123 Query: 151 HECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLD 210 HEC + + F ECK +Y+ +++ D F+CLP+AA+++++ C HGGLSP++ +++ Sbjct: 124 HECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183 Query: 211 DIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQ 270 IR++ R + P G +CD+LWSDP +K + + N RG S+ + V +FL Sbjct: 184 QIRRIMRPTDVPDQGLLCDLLWSDP------DKDVQGWGEND-RGVSFTFGAEVVAKFLH 236 Query: 271 HNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329 ++L I RAH+ + GY + K Q L+T+FSAPNY ++N A++ + +M Sbjct: 237 KHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM 289 >4ZVZ-A nrPDB Length = 333 Score = 419 bits (1076), Expect = e-117, Method: Composition-based stats. Identities = 121/319 (37%), Positives = 181/319 (56%), Gaps = 27/319 (8%) Query: 38 DGKPRVDILKAHLMK----EGRLEESVALRIITEGASILRQEKNLLDID----APVTVCG 89 DGK + +K LM+ + +L A +I+ + +L + L++ +TVCG Sbjct: 17 DGKVTISFMK-ELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCG 75 Query: 90 DIHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLR 148 D HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLR Sbjct: 76 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 135 Query: 149 GNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGL-SPEIN 207 GNHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL S + Sbjct: 136 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 195 Query: 208 TLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCE 267 TLDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + Sbjct: 196 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISK--------RGVSCQFGPDVTKA 247 Query: 268 FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 327 FL+ NNL I+R+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 248 FLEENNLDYIIRSHEVKAEGYEVAHGGRC------VTVFSAPNYCDQMGNKASYIHLQGS 301 Query: 328 VM--NIRQFNCSPHPYWLP 344 + QF PHP P Sbjct: 302 DLRPQFHQFTAVPHPNVKP 320 >5JJT-A nrPDB Length = 479 Score = 415 bits (1068), Expect = e-116, Method: Composition-based stats. Identities = 125/327 (38%), Positives = 181/327 (55%), Gaps = 30/327 (9%) Query: 40 KPRVDILKA---HLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIH 92 + +D +K + L + A +I+ + IL +L+DI P +TVCGD+H Sbjct: 167 EVTLDFVKTMMEDFKNQKTLHKRYAYQIVLQTRQILLALPSLVDISVPHGKHITVCGDVH 226 Query: 93 GQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNH 151 GQF+DL+ +FE+ G P+ YLF GD+VDRG FS+E +L L+A K + P +++L RGNH Sbjct: 227 GQFYDLLNIFELNGLPSEENPYLFNGDFVDRGSFSVEIILTLFAFKCMCPSSIYLARGNH 286 Query: 152 ECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGL-SPEINTLD 210 E + + + + F+ E + K SE+ D + F LPLA ++N + VHGGL S + L Sbjct: 287 ESKSMNKIYGFEGEVRSKLSEKFVDLFAEVFCYLPLAHVINGKVFVVHGGLFSVDGVKLS 346 Query: 211 DIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQ 270 DIR +DRF EPP G MC++LWSDP G ++ RG + FLQ Sbjct: 347 DIRAIDRFCEPPEEGLMCELLWSDPQPLPGRGPSK--------RGVGLSFGGDVTKRFLQ 398 Query: 271 HNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM- 329 NNL ++R+HE +D GY + + LIT+FSAPNY D NK A +++E M Sbjct: 399 DNNLDLLVRSHEVKDEGYEVEHDGK------LITVFSAPNYCDQMGNKGAFIRFEAPDMK 452 Query: 330 -NIRQFNCSPHPYWLP-----NFMDVF 350 NI F+ PHP P NF+ +F Sbjct: 453 PNIVTFSAVPHPDVKPMAYANNFLRMF 479 >4JA9-A nrPDB Length = 488 Score = 414 bits (1063), Expect = e-116, Method: Composition-based stats. Identities = 120/319 (37%), Positives = 180/319 (56%), Gaps = 27/319 (8%) Query: 38 DGKPRVDILKAHLMK----EGRLEESVALRIITEGASILRQEKNLLDID----APVTVCG 89 DGK + +K LM+ + +L A +I+ + +L + L++ +TVCG Sbjct: 172 DGKVTITFMK-DLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCG 230 Query: 90 DIHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLR 148 D HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLR Sbjct: 231 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 290 Query: 149 GNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGL-SPEIN 207 GNHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL S + Sbjct: 291 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 350 Query: 208 TLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCE 267 TLDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + Sbjct: 351 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSK--------RGVSCQFGPDVTKA 402 Query: 268 FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 327 FL+ N L I+R+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 403 FLEENQLDYIIRSHEVKAEGYEVAHGGRC------VTVFSAPNYCDQMGNKASYIHLQGS 456 Query: 328 VM--NIRQFNCSPHPYWLP 344 + QF PHP P Sbjct: 457 DLRPQFHQFTAVPHPNVKP 475 >5W0W-C nrPDB Length = 311 Score = 409 bits (1051), Expect = e-114, Method: Composition-based stats. Identities = 125/298 (41%), Positives = 174/298 (58%), Gaps = 16/298 (5%) Query: 43 VDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLF 102 +D L + +L ES + + IL +E N+ ++ PVTVCGD+HGQF DLM+LF Sbjct: 12 LDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELF 71 Query: 103 EVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTF 162 +GG +T YLF+GDYVDRGY+S+E V L ALK+ Y + + +LRGNHE R +T+ + F Sbjct: 72 RIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGF 131 Query: 163 KQECKIKY-SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEP 221 EC KY + V+ D FD LPL AL++ Q C+HGGLSP I+TLD IR LDR +E Sbjct: 132 YDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEV 191 Query: 222 PAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAH 281 P GPMCD+LWSDP +D G + RG Y + F N L + RAH Sbjct: 192 PHEGPMCDLLWSDP-DDRGGWGI-------SPRGAGYTFGQDISETFNHANGLTLVSRAH 243 Query: 282 EAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV-MNIRQFNCSP 338 + GY +++TIFSAPNY N+AA+++ ++ + + QF+ +P Sbjct: 244 QLVMEGYNWCHDR------NVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP 295 >5JPE-A nrPDB Length = 311 Score = 408 bits (1049), Expect = e-114, Method: Composition-based stats. Identities = 109/298 (36%), Positives = 167/298 (56%), Gaps = 22/298 (7%) Query: 41 PRVDILKAHLMK---EGRLEESVALR------IITEGASILRQEKNLLDIDAPVTVCGDI 91 +D L L+ G+ ++V L+ I I + +LL++ PV V GD+ Sbjct: 4 IDIDSLIDKLLNAGFSGKRTKNVCLKNTEIELICASAREIFLSQPSLLELAPPVKVVGDV 63 Query: 92 HGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNH 151 HGQ+ DL+++F G P T YLFLGDYV+RG S+E +L L KI YP+ FLLRGNH Sbjct: 64 HGQYHDLIRIFSKCGFPPKTNYLFLGDYVNRGKQSLETILLLLCYKIKYPENFFLLRGNH 123 Query: 152 ECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDD 211 EC ++T + F ECK + + + + +D F+ LP+AA++ + CVHGGLSP +N++D+ Sbjct: 124 ECANVTRVYGFYDECKRRCNIKTWKLFIDTFNTLPIAAIVAGKIFCVHGGLSPVLNSMDE 183 Query: 212 IRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQH 271 IR + R + P +G + D+LWSDP + + E RG SY +S A+ +FL Sbjct: 184 IRNIARPTDVPDFGLLNDLLWSDPADTINEWEDNE-------RGVSYVFSKVAINKFLSK 236 Query: 272 NNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329 N + RAH + GY + +L+T+FSAPNY ++N AV+ +++ Sbjct: 237 FNFDLVCRAHMVVEDGYEFFNDR------TLVTVFSAPNYCGEFDNWGAVMGVSEDLL 288 >3ICF-A nrPDB Length = 335 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 111/316 (35%), Positives = 167/316 (52%), Gaps = 36/316 (11%) Query: 50 LMKEGRLEESVALRIITEGASILRQEKNLLDI------DAPVTVCGDIHGQFFDLMKLFE 103 +K L + II+ ++ RQE +++++ D ++VCGD HGQF+D++ LF Sbjct: 25 FLKGKYLPKKYVAAIISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFR 84 Query: 104 VGG--SPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFT 161 G P +T YLF GD+VDRG +S E L + LKIL+P FL RGNHE ++ + + Sbjct: 85 KFGKVGPKHT-YLFNGDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYG 143 Query: 162 FKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGL-SPEINTLDDIRKLDRFKE 220 F+ ECK KYS+R+++ +F+ LPLA L+N +L +HGGL S TL D + +DRF + Sbjct: 144 FEDECKYKYSQRIFNMFAQSFESLPLATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQ 203 Query: 221 PPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRA 280 PP G ++LW+DP E G +Q RG + + FL++N L I R+ Sbjct: 204 PPRDGAFMELLWADPQEANGMGPSQ--------RGLGHAFGPDITDRFLRNNKLRKIFRS 255 Query: 281 HEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKY------------ENNV 328 HE + G + +K + L+T+FSAPNY D N V+ ++ Sbjct: 256 HELRMGGVQFEQKGK------LMTVFSAPNYCDSQGNLGGVIHVVPGHGILQAGRNDDQN 309 Query: 329 MNIRQFNCSPHPYWLP 344 + I F HP P Sbjct: 310 LIIETFEAVEHPDIKP 325 >1V73-A nrPDB Length = 342 Score = 50.8 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 52/237 (21%), Positives = 87/237 (36%), Gaps = 35/237 (14%) Query: 84 PVTVCGDIHGQFFDLMKLFEVGG-SPANTRYLF-------LGDYVDRGYFSIECVLYLWA 135 V D+HGQ+ L+ L + ++ + F GD DRG+ E + +++ Sbjct: 72 KVVALSDVHGQYDVLLTLLKKQKIIDSDGNWAFGEGHMVMTGDIFDRGHQVNEVLWFMYQ 131 Query: 136 LKILYPKT---LFLLRGNHEC-------RHLTEYFTFKQECKIKYSERVYDACMDAFDCL 185 L + LL GNHE R++ + + + ++Y A + L Sbjct: 132 LDQQARDAGGMVHLLMGNHEQMVLGGDLRYVHQRYDIATTLINRPYNKLYGADTEIGQWL 191 Query: 186 PLAALM--NQQFLCVHGGLSPE----INTLDDIRKLDR-FKEPPAYGPMCDILWSDPLED 238 + L +HGG+S E TLD L R + D L + Sbjct: 192 RSKNTIIKINDVLYMHGGISSEWISRELTLDKANALYRANVDASKKSLKADDLLN--FLF 249 Query: 239 FGNEKTQEHFTHNTVRG-CSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294 FGN T RG S ++ + LQH N+ I+ H +Q+ ++ Sbjct: 250 FGNGPT-------WYRGYFSETFTEAELDTILQHFNVNHIVVGHTSQERVLGLFHNK 299 >1G5B-A nrPDB Length = 221 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 7/69 (10%) Query: 85 VTVCGDIHGQFFDLMKLFEVGGSPANTRYLF-LGDYVDRGYFSIECVLYLWALKILYPKT 143 + V GD+HG + +LM + G L +GD VDRG ++EC+ I +P Sbjct: 15 IWVVGDLHGCYTNLMNKLDTIGFDNKKDLLISVGDLVDRGAENVECLEL-----ITFP-W 68 Query: 144 LFLLRGNHE 152 +RGNHE Sbjct: 69 FRAVRGNHE 77 >2F2P-A nrPDB Length = 179 Score = 47.7 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 35/67 (52%), Positives = 43/67 (64%), Gaps = 10/67 (14%) Query: 357 VGEKVTEMLVNVL----NICSDDELGSEE------DGFDGATAAARKEVIRNKIRAIGKM 406 +GEK+T+ V+ + +I D ++ EE G AAARKEVIRNKIRAIGKM Sbjct: 113 LGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGAAARKEVIRNKIRAIGKM 172 Query: 407 ARVFSVL 413 ARVFSVL Sbjct: 173 ARVFSVL 179 >2DFJ-A nrPDB Length = 280 Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 31/127 (24%), Positives = 57/127 (44%), Gaps = 17/127 (13%) Query: 89 GDIHGQFFDLMKLFEVGGSPANTRYLFL-GDYVDRGYFSIECVLYLWALKILYPKTLFLL 147 GD+HG + +L+ L L+L GD V RG S++ + Y+ +L ++ L+ Sbjct: 7 GDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLG----DSVRLV 62 Query: 148 RGNHECRHLTEYFTFKQECKIKYSERVYDACM-----DAFDCL---PLAALMNQQFLCV- 198 GNH+ L F + K +R+ + + L PL + ++ L + Sbjct: 63 LGNHD---LHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMA 119 Query: 199 HGGLSPE 205 H G++P+ Sbjct: 120 HAGITPQ 126 >5VJW-A nrPDB Length = 309 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 8/74 (10%) Query: 87 VC-GDIHGQFFDLMKLF---EVGGSPAN---TRYLFLGDYVDRGYFSIECVLYLWALKIL 139 +C GDIHG L L+ + P++ +FLGDY DRG + + + +L +L Sbjct: 9 ICVGDIHGYISKLNNLWLNLQSAIDPSDFSSALVIFLGDYCDRGPETRKVIDFLISLPEK 68 Query: 140 YPKTLFL-LRGNHE 152 +P + L GNH+ Sbjct: 69 HPDQTHVFLAGNHD 82 >2LHI-A nrPDB Length = 176 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 25/67 (37%), Positives = 38/67 (56%), Gaps = 6/67 (8%) Query: 354 LPFVGEKVTEMLVN-VLNICSDDELGSEEDGF-----DGATAAARKEVIRNKIRAIGKMA 407 L +GEK+T+ V+ +L SD F G++ R++ +RNKI AI K++ Sbjct: 110 LTSIGEKLTDAEVDDMLREVSDGSGEINIQQFAALLSKGSSTGTRRKALRNKILAIAKVS 169 Query: 408 RVFSVLR 414 R+FSVLR Sbjct: 170 RMFSVLR 176 >6DJW-A nrPDB Length = 349 Score = 32.3 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 53/264 (20%), Positives = 91/264 (34%), Gaps = 32/264 (12%) Query: 18 VKAVPFPPSHRL--TAKEVFDNDGKPRVDILKAHLMKEGRLEESVAL---RIITEGASIL 72 +++ P P RL T E+ + D + H + +L + + GA + Sbjct: 80 IRSRPQPQRQRLQSTVMEITEEDRQRTKAHFFVHCAQCNKLCKGKLRVRCSLCKGGAFTV 139 Query: 73 RQEKNLLD-IDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFL-GDYVDRGYFSIECV 130 ++ D + P + G H + ++ G P T + F G++V G Sbjct: 140 HRDPECWDDVLKPRRITG--HCESQEIACFDNETGDPPFTEFYFKCGEHVSGGEKDFAAP 197 Query: 131 LYLWALKILYPKTL-------FLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFD 183 L L + I L +L E +H+T F+Q C+ + SER + D Sbjct: 198 LNLIKINIKDVPCLACTEVSETVLVFPCESKHVTCLECFEQYCRSRLSERQFMPHPDIGY 257 Query: 184 CLPL-AALMNQQFLCVHGGLSPEINTLDDIRKLDRFKE----PPAYGPMCDILWSDPLED 238 LP A N +H ++ + ++ + RF A G +C P Sbjct: 258 TLPCPAGCENSFIEEIH---HFKLLSREEYARYQRFATEEYVLQAGGVLC------PQPG 308 Query: 239 FGNEKTQEHFTHNTV--RGCSYFY 260 G E GC Y + Sbjct: 309 CGMGLLVEPECKKVTCQNGCGYVF 332 >4CKE-A nrPDB Length = 844 Score = 32.3 bits (72), Expect = 0.51, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 23/58 (39%) Query: 16 RVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILR 73 ++ +P H L K V D + K L+ E RL + LR+ TE I Sbjct: 75 KIRTKIPLSKVHGLDVKNVQLVDAIDNIVWEKKSLVTENRLHKECLLRLSTEERHIFL 132 >1YQX-A nrPDB Length = 366 Score = 32.3 bits (72), Expect = 0.59, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 46/109 (42%), Gaps = 1/109 (0%) Query: 375 DELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPS 434 D D AA + I + + A+ + +F +L+ + +L P LP+ Sbjct: 234 DSFLVSRDQEQMQAAAGTLDGIIDTVSAVHPLLPLFGLLKSHGKLILVGAPEKPL-ELPA 292 Query: 435 GVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRINERM 483 L G++ + + + ++ + + F+ +H IT+ E D +N M Sbjct: 293 FSLIAGRKIVAGSGIGGMKETQEMIDFAAKHNITADIEVISTDYLNTAM 341 >6CV7-A nrPDB Length = 377 Score = 31.6 bits (70), Expect = 0.79, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 28/81 (34%), Gaps = 11/81 (13%) Query: 202 LSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYS 261 ++P I +D R + + P G + IL P + F H R Sbjct: 279 VTPPIQAIDQDRNIQPPSDRP--GILYSILVGTPEDYP-------RFFHMHPRTAELTLL 329 Query: 262 YPAVCEFLQHNNLLSILRAHE 282 P +F H +++A + Sbjct: 330 EPVNRDF--HQKFDLVIKAEQ 348 >1KAN-A nrPDB Length = 253 Score = 31.6 bits (70), Expect = 0.95, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 5/40 (12%) Query: 68 GASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGS 107 IL + ++ D P+T HGQFF ++ +++ GG Sbjct: 81 SEEILLDYASQVESDWPLT-----HGQFFSILPIYDSGGY 115 >3WF0-A nrPDB Length = 678 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 26/136 (19%), Positives = 48/136 (35%), Gaps = 27/136 (19%) Query: 68 GASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKL---FEV---GGSPANTRYLFLGDYVD 121 S + D DAP++ GD+ ++F L + FE G P +T G Sbjct: 321 ANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTL 380 Query: 122 RGYFSIECVLYLWA----LKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDA 177 ++ L + +K LYP T + +++ F + + Sbjct: 381 EKLKTVGAALDILCPSGPIKSLYPLTFI---------QVKQHYGF---VLYRTT-----L 423 Query: 178 CMDAFDCLPLAALMNQ 193 D + PL++ +N Sbjct: 424 PQDCSNPAPLSSPLNG 439 >5T4M-A nrPDB Length = 365 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 28/81 (34%), Gaps = 11/81 (13%) Query: 202 LSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYS 261 ++P I +D R + + P G + IL P + F H R Sbjct: 41 VTPPIQAIDQDRNIQPPSDRP--GILYSILVGTPEDYP-------RFFHMHPRTAELSLL 91 Query: 262 YPAVCEFLQHNNLLSILRAHE 282 P +F H +++A + Sbjct: 92 EPVNRDF--HQKFDLVIKAEQ 110 >2FAH-A nrPDB Length = 608 Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 17/58 (29%), Gaps = 8/58 (13%) Query: 217 RFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNL 274 RF P P+ D W DP G F RG V F + + Sbjct: 391 RFCAPADQCPIMDPRWDDPE---GVPIDAIIFGGRRPRGV-----PLVVEAFGWRHGV 440 >2CV2-A nrPDB Length = 468 Score = 30.8 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 14/117 (11%) Query: 39 GKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLL-DIDAPVTVCGDIHGQFFD 97 G P D+ K M + E ++L + E +E L + +A + ++ FD Sbjct: 301 GGPVFDLEKLRWMNGKYIREVLSLEEVAERVKPFLREAGLSWESEAYLRRAVELMRPRFD 360 Query: 98 LMKLFEVGGSPANTRYLFLGDY--VDRGYFSIECVLYLWALKILYPKTLFLLRGNHE 152 +K F P RYLF DY ++ +E L L LK LYP+ LR E Sbjct: 361 TLKEF-----PEKARYLFTEDYPVSEKAQRKLEEGLPL--LKELYPR----LRAQEE 406 >5ULY-A nrPDB Length = 259 Score = 30.8 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 28/81 (34%), Gaps = 11/81 (13%) Query: 202 LSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYS 261 ++P I +D R + + P G + IL P + F H R Sbjct: 161 VTPPIQAIDQDRNIQPPSDRP--GILYSILVGTPEDYP-------RFFHMHPRTAELSLL 211 Query: 262 YPAVCEFLQHNNLLSILRAHE 282 P +F H +++A + Sbjct: 212 EPVNRDF--HQKFDLVIKAEQ 230 >4AZV-A nrPDB Length = 569 Score = 29.2 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 4/82 (4%) Query: 230 ILWSDPLEDFGNEKTQE--HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAG 287 +L +D + F + + Q R YF+ VC+F ++ IL A E+Q Sbjct: 226 VLINDFNQPFQHWQNQPYAGAGLAHKRSRRYFFGEDYVCKFFYYDMPHGILTAEESQRNK 285 Query: 288 YRMYRKSQTTGFPSLITIFSAP 309 Y ++ + + P F AP Sbjct: 286 YELHNEIKFLTQPP--AGFDAP 305 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.136 0.391 Lambda K H 0.267 0.0411 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,998,896 Number of Sequences: 36641 Number of extensions: 857111 Number of successful extensions: 2185 Number of sequences better than 10.0: 31 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 2078 Number of HSP's gapped (non-prelim): 64 length of query: 521 length of database: 10,336,785 effective HSP length: 101 effective length of query: 420 effective length of database: 6,636,044 effective search space: 2787138480 effective search space used: 2787138480 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.1 bits)