BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q07813 (192 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5W62-A nrPDB 385 e-108 5W61-A nrPDB 349 5e-97 4BD6-A nrPDB 312 5e-86 5W5Z-A nrPDB 298 8e-82 5W63-A nrPDB 207 3e-54 4BDU-A nrPDB 147 2e-36 4IEH-A nrPDB 70 8e-13 2PON-B nrPDB 68 2e-12 4CIM-A nrPDB 66 9e-12 3ZK6-A nrPDB 66 9e-12 2O2F-A nrPDB 65 1e-11 4QVX-A nrPDB 65 2e-11 2BZW-A nrPDB 65 2e-11 4QNQ-A nrPDB 65 2e-11 4C5D-A nrPDB 65 3e-11 2XA0-A nrPDB 64 3e-11 2O2N-A nrPDB 63 6e-11 2W3L-A nrPDB 62 1e-10 5WDD-A nrPDB 62 2e-10 4K5A-A nrPDB 62 2e-10 2JCN-A nrPDB 59 2e-09 4WMS-A nrPDB 57 5e-09 3PK1-A nrPDB 57 5e-09 1WSX-A nrPDB 57 6e-09 5JSB-A nrPDB 56 7e-09 3IO9-A nrPDB 54 3e-08 6CKV-A nrPDB 54 3e-08 3I1H-A nrPDB 54 5e-08 2VOG-A nrPDB 49 2e-06 6FBX-A nrPDB 48 2e-06 3QBR-A nrPDB 47 6e-06 5TWA-A nrPDB 45 1e-05 5UA4-A nrPDB 38 0.003 4U2V-B nrPDB 37 0.004 1K3K-A nrPDB 35 0.017 5WOS-A nrPDB 33 0.078 5KTG-A nrPDB 32 0.11 5TZP-A nrPDB 32 0.13 5VMN-A nrPDB 32 0.22 4B4S-A nrPDB 32 0.23 3ZCN-A nrPDB 32 0.23 1DDB-A nrPDB 28 1.8 3Q60-A nrPDB 28 2.1 1OQP-A nrPDB 28 3.4 3QRX-A nrPDB 27 3.8 4QUV-A nrPDB 27 3.9 2GU2-A nrPDB 27 5.9 3UKM-A nrPDB 27 7.4 2REK-A nrPDB 26 8.9 5OTJ-D nrPDB 26 9.1 >5W62-A nrPDB Length = 192 Score = 385 bits (988), Expect = e-108, Method: Compositional matrix adjust. Identities = 190/192 (98%), Positives = 190/192 (98%) Query: 1 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS 60 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS Sbjct: 1 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS 60 Query: 61 ECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL 120 E LRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL Sbjct: 61 ESLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL 120 Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGV 180 VLKAL TKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGV Sbjct: 121 VLKALSTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGV 180 Query: 181 LTASLTIWKKMG 192 LTASLTIWKKMG Sbjct: 181 LTASLTIWKKMG 192 >5W61-A nrPDB Length = 194 Score = 349 bits (895), Expect = 5e-97, Method: Compositional matrix adjust. Identities = 174/192 (90%), Positives = 178/192 (92%) Query: 1 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS 60 MDGSGEQ GGPTSSEQIMKTGA LLQGFIQDRAGRM GE PEL L+ PQDASTKKLS Sbjct: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60 Query: 61 ECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL 120 E L+RIGDELDSNMELQRMIA VDTDSPREVFFRVAADMF+DGNFNWGRVVALFYFASKL Sbjct: 61 ESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120 Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGV 180 VLKAL TKVPELIRTIMGWTLDFLRERLL WIQDQGGW+GLLSYFGT TWQTVTIFVAGV Sbjct: 121 VLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTGTWQTVTIFVAGV 180 Query: 181 LTASLTIWKKMG 192 LTASLTIWKKMG Sbjct: 181 LTASLTIWKKMG 192 >4BD6-A nrPDB Length = 174 Score = 312 bits (800), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 154/171 (90%), Positives = 158/171 (92%) Query: 1 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS 60 MDGSGEQ GGPTSSEQIMKTGA LLQGFIQDRAGRM GE PEL L+ PQDASTKKLS Sbjct: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60 Query: 61 ECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL 120 E L+RIGDELDSNMELQRMIA VDTDSPREVFFRVAADMF+DGNFNWGRVVALFYFASKL Sbjct: 61 ESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120 Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQ 171 VLKAL TKVPELIRTIMGWTLDFLRERLL WIQDQGGW+GLLSYFGTPTWQ Sbjct: 121 VLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQ 171 >5W5Z-A nrPDB Length = 163 Score = 298 bits (764), Expect = 8e-82, Method: Compositional matrix adjust. Identities = 147/161 (91%), Positives = 151/161 (93%) Query: 32 QDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNMELQRMIADVDTDSPREV 91 QDRAGRM GE PEL L+ PQDASTKKLSE L+RIGDELDSNMELQRMIA VDTDSPREV Sbjct: 1 QDRAGRMGGEAPELALDPVPQDASTKKLSESLKRIGDELDSNMELQRMIAAVDTDSPREV 60 Query: 92 FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVW 151 FFRVAADMF+DGNFNWGRVVALFYFASKLVLKAL TKVPELIRTIMGWTLDFLRERLL W Sbjct: 61 FFRVAADMFSDGNFNWGRVVALFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGW 120 Query: 152 IQDQGGWEGLLSYFGTPTWQTVTIFVAGVLTASLTIWKKMG 192 IQDQGGW+GLLSYFGT TWQTVTIFVAGVLTASLTIWKKMG Sbjct: 121 IQDQGGWDGLLSYFGTGTWQTVTIFVAGVLTASLTIWKKMG 161 >5W63-A nrPDB Length = 189 Score = 207 bits (526), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 97/185 (52%), Positives = 138/185 (74%), Gaps = 4/185 (2%) Query: 9 GSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQ----PPQDASTKKLSECLR 64 G G TS++QI++ GA LL+ FI +R R ++ + D + KKL++ L+ Sbjct: 4 GEGDGTSNDQILEVGAVLLKDFIYERVHRHGDSGTVVSRHELGGSELSDPTHKKLAQYLQ 63 Query: 65 RIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKA 124 +IGDELD+N++LQRM+AD +EVF +VA ++F+DG FNWGRVVALFYFAS+LV++A Sbjct: 64 QIGDELDNNVDLQRMLADSALQPTKEVFVKVAREIFSDGKFNWGRVVALFYFASRLVIEA 123 Query: 125 LCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGVLTAS 184 L TK+P++IRTI+ WTLD+LRE ++ WI++QGGWEG+ +YFGTPTW+TV +F+AGVLT Sbjct: 124 LLTKIPDIIRTIINWTLDYLREHVINWIREQGGWEGIQTYFGTPTWKTVGVFLAGVLTTV 183 Query: 185 LTIWK 189 L + K Sbjct: 184 LVMRK 188 >4BDU-A nrPDB Length = 311 Score = 147 bits (372), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 71/76 (93%), Positives = 73/76 (96%) Query: 53 DASTKKLSECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVA 112 DASTKKLSE L+RIGDELDSNMELQRMIA VDTDSPREVFFRVAADMF+DGNFNWGRVVA Sbjct: 236 DASTKKLSESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVA 295 Query: 113 LFYFASKLVLKALCTK 128 LFYFASKLVLKAL TK Sbjct: 296 LFYFASKLVLKALSTK 311 >4IEH-A nrPDB Length = 169 Score = 69.7 bits (169), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 46/168 (27%), Positives = 80/168 (47%), Gaps = 16/168 (9%) Query: 7 QLGSGGPTSSEQIMKTGAFLL--QGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLR 64 G G + E +MK + L +G+ D AG+ E + P+ ++ + LR Sbjct: 6 HAGRTGYDNREIVMKYIHYKLSQRGYEWD-----AGDDVEENRTEAPEGTESEVVHLTLR 60 Query: 65 RIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVALFYFAS 118 + GD D + +R A++ + + R F V ++F DG NWGR+VA F F Sbjct: 61 QAGD--DFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDG-VNWGRIVAFFEFGG 117 Query: 119 KLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFG 166 + ++++ ++ L+ I W ++L L WIQD GGW+ + +G Sbjct: 118 VMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 165 >2PON-B nrPDB Length = 156 Score = 68.2 bits (165), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 34/124 (27%), Positives = 65/124 (52%), Gaps = 9/124 (7%) Query: 49 QPPQDASTKKLSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFAD 102 + P+ ++ + + LR GDE + + +R +D+ + + + F +V ++F D Sbjct: 36 EAPEGTESEAVKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRD 93 Query: 103 GNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLL 162 G NWGR+VA F F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + Sbjct: 94 G-VNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFV 152 Query: 163 SYFG 166 +G Sbjct: 153 ELYG 156 >4CIM-A nrPDB Length = 163 Score = 66.2 bits (160), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 9/123 (7%) Query: 50 PPQDASTKKLSECLRRIGDELDSNMELQRMIAD------VDTDSPREVFFRVAADMFADG 103 P + + L + LR IGDE ++ +R +D V S ++ F +V+ ++F G Sbjct: 33 PGEGPAADPLGQALRAIGDEFETR--FRRTFSDLAAQLHVTPGSAQQRFTQVSDELF-QG 89 Query: 104 NFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLS 163 NWGR+VA F F + L +++ ++ L+ + W +++L RL WI GGW + Sbjct: 90 GPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVEYLETRLADWIHSSGGWAEFTA 149 Query: 164 YFG 166 +G Sbjct: 150 LYG 152 >3ZK6-A nrPDB Length = 181 Score = 66.2 bits (160), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 34/125 (27%), Positives = 63/125 (50%), Gaps = 9/125 (7%) Query: 49 QPPQDASTKKLSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFAD 102 + P+ + + LR GDE + + +R +D+ + + + F +V ++F D Sbjct: 40 EAPEGIPMAAVKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRD 97 Query: 103 GNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLL 162 G NWGR+VA F F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + Sbjct: 98 G-VNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFV 156 Query: 163 SYFGT 167 +G Sbjct: 157 ELYGN 161 >2O2F-A nrPDB Length = 138 Score = 65.5 bits (158), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 18/155 (11%) Query: 12 GPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELD 71 G + E +MK + L + G E LTL Q D S + RR E+ Sbjct: 1 GYDNREIVMKYIHYKLS-----QRGYEWDEVVHLTLRQAGDDFSRR-----YRRDFAEMS 50 Query: 72 SNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPE 131 S + L A R F V ++F DG NWGR+VA F F + ++++ ++ Sbjct: 51 SQLHLTPFTA-------RGRFATVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSP 102 Query: 132 LIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFG 166 L+ I W ++L L WIQD GGW+ + +G Sbjct: 103 LVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 137 >4QVX-A nrPDB Length = 167 Score = 65.1 bits (157), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 34/115 (29%), Positives = 59/115 (51%), Gaps = 9/115 (7%) Query: 59 LSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVA 112 + + LR GDE + + +R +D+ + + + F +V ++F DG NWGR+VA Sbjct: 36 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 92 Query: 113 LFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGT 167 F F L ++++ K+ L+ I W +L + L WIQ+ GGW + +G Sbjct: 93 FFSFGGALCVESVDKKMQVLVSRIAAWMATYLNDHLEPWIQENGGWATFVELYGN 147 >2BZW-A nrPDB Length = 211 Score = 64.7 bits (156), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 9/115 (7%) Query: 59 LSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVA 112 + + LR GDE + + +R +D+ + + + F +V ++F DG NWGR+VA Sbjct: 86 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 142 Query: 113 LFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGT 167 F F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 143 FFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGN 197 >4QNQ-A nrPDB Length = 240 Score = 64.7 bits (156), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 9/115 (7%) Query: 59 LSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVA 112 + + LR GDE + + +R +D+ + + + F +V ++F DG NWGR+VA Sbjct: 93 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 149 Query: 113 LFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGT 167 F F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 150 FFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGN 204 >4C5D-A nrPDB Length = 158 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 9/115 (7%) Query: 59 LSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVA 112 + + LR GDE + + +R +D+ + + + F +V ++F DG NWGR+VA Sbjct: 35 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 91 Query: 113 LFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGT 167 F F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 92 FFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN 146 >2XA0-A nrPDB Length = 207 Score = 64.3 bits (155), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 39/123 (31%), Positives = 58/123 (47%), Gaps = 13/123 (10%) Query: 44 ELTLEQPPQDASTKKLSECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADG 103 LTL Q D S + RR E+ S + L A R F V ++F DG Sbjct: 94 HLTLRQAGDDFSRR-----YRRDFAEMSSQLHLTPFTA-------RGRFATVVEELFRDG 141 Query: 104 NFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLS 163 NWGR+VA F F + ++++ ++ L+ I W ++L L WIQD GGW+ + Sbjct: 142 -VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVE 200 Query: 164 YFG 166 +G Sbjct: 201 LYG 203 >2O2N-A nrPDB Length = 145 Score = 63.2 bits (152), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 33/114 (28%), Positives = 60/114 (52%), Gaps = 9/114 (7%) Query: 59 LSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVA 112 + + LR GDE + + +R +D+ + + + F +V ++F DG NWGR+VA Sbjct: 35 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 91 Query: 113 LFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFG 166 F F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 92 FFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 145 >2W3L-A nrPDB Length = 144 Score = 62.4 bits (150), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 9/119 (7%) Query: 54 ASTKKLSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNW 107 A ++ + + LR GD D + +R A++ + + R F V ++F DG NW Sbjct: 26 ADSEVVHKTLREAGD--DFSRRYRRDFAEMSSGLHLTPFTARGRFATVVEELFRDG-VNW 82 Query: 108 GRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFG 166 GR+VA F F + ++++ ++ L+ I W ++L L WIQD GGW+ + +G Sbjct: 83 GRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 141 >5WDD-A nrPDB Length = 168 Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 8/158 (5%) Query: 8 LGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIG 67 LGS + ++++ L + +I R R + P ++S L R+G Sbjct: 3 LGSDRSPTDKELVSQAKALCRDYINSRLIRAGVSWSKPEHNTPVPGGKLAEVSAILLRLG 62 Query: 68 DELD-------SNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL 120 DEL+ N+ Q I+ + F VAA +F G WG+VV+L+ A+ L Sbjct: 63 DELEYIRPNVYRNIARQLNISLHSETVVTDAFLAVAAQIFTAG-ITWGKVVSLYAVAAGL 121 Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGW 158 + + P ++ TI+ +F+R+ L+ W++ +GGW Sbjct: 122 AVDCVRHAQPAMVHTIVDCLGEFVRKTLVTWLKRRGGW 159 >4K5A-A nrPDB Length = 184 Score = 61.6 bits (148), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 9/123 (7%) Query: 50 PPQDASTKKLSECLRRIGDELDSNMELQRMIAD------VDTDSPREVFFRVAADMFADG 103 P + + L + +R GDE ++ +R +D V S ++ F +V+ ++F G Sbjct: 44 PGEGPAADPLHQAMRAAGDEFETR--FRRTFSDLAAQLHVTPGSAQQRFTQVSDELF-QG 100 Query: 104 NFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLS 163 NWGR+VA F F + L +++ ++ L+ + W + +L RL WI GGW + Sbjct: 101 GPNWGRLVAFFVFGAALCAESVNKEMEVLVGQVQEWMVAYLETRLADWIHSSGGWAEFTA 160 Query: 164 YFG 166 +G Sbjct: 161 LYG 163 >2JCN-A nrPDB Length = 172 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 47/174 (27%), Positives = 80/174 (45%), Gaps = 12/174 (6%) Query: 1 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTK-KL 59 M S EQ+ +E++ ++ F Q+ G A PE+ + P Q +ST ++ Sbjct: 2 MSASEEQVAQ----DTEEVFRSYVFYRHQQEQEAEGVAAPADPEM-VTLPLQPSSTMGQV 56 Query: 60 SECLRRIGDELDS--NMELQRMIADVD--TDSPREVFFRVAADMFADGNFNWGRVVALFY 115 L IGD+++ + E Q M+ + ++ E F ++A +F G NWGRVVAL Sbjct: 57 GRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESG-INWGRVVALLG 115 Query: 116 FASKLVLKALCTKVPELIRTIMGWTLDFLRERLLV-WIQDQGGWEGLLSYFGTP 168 F +L L + + + + +DF+ + WI +GGW L+ P Sbjct: 116 FGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWVAALNLGNGP 169 >4WMS-A nrPDB Length = 518 Score = 57.0 bits (136), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 6/117 (5%) Query: 54 ASTKKLSECLRRIGDELDSNME--LQRMIADVDTDSPREV--FFRVAADMFADGNFNWGR 109 A+++K E LRR+GD + N E Q M+ +D + +V RV +F+DG NWGR Sbjct: 401 ATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGR 460 Query: 110 VVALFYFASKLVLKALCTKVPE-LIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYF 165 +V L F + V K L T E I + D L W+ Q GW+G + +F Sbjct: 461 IVTLISFGA-FVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 516 >3PK1-A nrPDB Length = 189 Score = 57.0 bits (136), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 6/117 (5%) Query: 54 ASTKKLSECLRRIGDELDSNME--LQRMIADVDTDSPREV--FFRVAADMFADGNFNWGR 109 A+++K E LRR+GD + N E Q M+ +D + +V RV +F+DG NWGR Sbjct: 67 ATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGR 126 Query: 110 VVALFYFASKLVLKALCTKVPE-LIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYF 165 +V L F + V K L T E I + D L W+ Q GW+G + +F Sbjct: 127 IVTLISFGA-FVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 182 >1WSX-A nrPDB Length = 162 Score = 56.6 bits (135), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 4/116 (3%) Query: 54 ASTKKLSECLRRIGDELDSNME--LQRMIADVDTDSPREV--FFRVAADMFADGNFNWGR 109 A+ ++ E LRR+GD + N E Q M+ +D + +V F RV +F DG NWGR Sbjct: 39 AAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRVMVHVFKDGVTNWGR 98 Query: 110 VVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYF 165 +V L F + + I + D L W+ Q GW+G + +F Sbjct: 99 IVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVRTKRDWLVKQRGWDGFVEFF 154 >5JSB-A nrPDB Length = 179 Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 6/117 (5%) Query: 54 ASTKKLSECLRRIGDELDSNME--LQRMIADVDTDSPREV--FFRVAADMFADGNFNWGR 109 A+++K E LRR+GD + N E Q M+ +D + +V RV +F+DG NWGR Sbjct: 33 ATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGR 92 Query: 110 VVALFYFASKLVLKALCTKVPE-LIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYF 165 +V L F + V K L T E I + D L W+ Q GW+G + +F Sbjct: 93 IVTLISFGA-FVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 148 >3IO9-A nrPDB Length = 162 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 6/117 (5%) Query: 54 ASTKKLSECLRRIGDELDSNME--LQRMIADVDTDSPREV--FFRVAADMFADGNFNWGR 109 A+ ++ E LRR+GD + N E Q M+ +D + +V RV +F+DG NWGR Sbjct: 39 AAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGR 98 Query: 110 VVALFYFASKLVLKALCTKVPE-LIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYF 165 +V L F + V K L T E I + D L W+ Q GW+G + +F Sbjct: 99 IVTLISFGA-FVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 154 >6CKV-A nrPDB Length = 158 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 41/159 (25%), Positives = 75/159 (47%), Gaps = 14/159 (8%) Query: 13 PTSSEQIMKTGAFLLQGFIQDRAGR--MAGETPELTLEQPPQDASTKKLSECLRRIGDEL 70 PT E + + A L + ++ R R ++ PE P +++ L R+GDEL Sbjct: 3 PTDKELVAQAKA-LGREYVHARLLRAGLSWSAPE---RAAPVPGRLAEVAAVLLRLGDEL 58 Query: 71 D-------SNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLK 123 + N+ Q I+ + F VA +F+ G WG+VV+L+ A+ L + Sbjct: 59 EMIRPSVYRNVARQLHISLQSERVVTDAFLAVAGHIFSAG-ITWGKVVSLYAVAAGLAVD 117 Query: 124 ALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLL 162 A+ P ++ ++ +F+R+ L W++ +GGW +L Sbjct: 118 AVRQAQPAMVHALVDALGEFVRKTLATWLRRRGGWTDVL 156 >3I1H-A nrPDB Length = 161 Score = 53.9 bits (128), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 36/132 (27%), Positives = 64/132 (48%), Gaps = 8/132 (6%) Query: 37 RMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNME--LQRMIADVDT---DSPREV 91 R+A + + L+ P + K S L+ + + +E L+ + +V+ D+ R + Sbjct: 21 RLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTL 80 Query: 92 FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKV-PEL--IRTIMGWTLDFLRERL 148 F +V F DG NWGR+V +F F L+ K L ++ P++ + I + +F+ Sbjct: 81 FNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNT 140 Query: 149 LVWIQDQGGWEG 160 WI+ GGWE Sbjct: 141 GEWIRQNGGWEN 152 >2VOG-A nrPDB Length = 157 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 9/137 (6%) Query: 38 MAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNME--LQRMIADVDT---DSPREVF 92 +A + L+ P +++ + L+R+ + +E L+ + D D+ R +F Sbjct: 17 LAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIF 76 Query: 93 FRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVP---ELIRTIMGWTLDFLRERLL 149 +V F DG NWGR+V +F F L+ K ++ + + + +F+ Sbjct: 77 NQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLKQEQIALDVSAYKQVSSFVAEFIMNNTG 136 Query: 150 VWIQDQGGWE-GLLSYF 165 WI+ GGWE G + F Sbjct: 137 EWIRQNGGWEDGFIKKF 153 >6FBX-A nrPDB Length = 152 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 11/122 (9%) Query: 50 PPQDASTKKLSECLRRIGDELDSNME-----LQRMIADVDTDSPREVFFRVAADMFADGN 104 PP +++ E +R + E++ L + D P + V ++ DG Sbjct: 31 PPSESA-----EAMRYLAKEMEQQHRTKFRSLSQEFLDTCGADPSKCLQSVMRELVGDGK 85 Query: 105 FNWGRVVALFYFASKLVLKALCT-KVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLS 163 NWGRVV++F F L + L + E R + D+L W+ + GGWEG Sbjct: 86 MNWGRVVSIFTFTGVLASELLSRGENSEGSRRLAETIADYLGGEKQDWLVENGGWEGFCR 145 Query: 164 YF 165 +F Sbjct: 146 FF 147 >3QBR-A nrPDB Length = 179 Score = 47.0 bits (110), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 8/90 (8%) Query: 83 VDTDSP-----REVFF-RVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTI 136 +D+D P E+F+ + +F NWGR+VA+F F LVL+ + I+ + Sbjct: 91 IDSDKPVDKTALEIFYLEILNGLFE--KLNWGRIVAMFAFLRILVLRLSKHGHSDAIQML 148 Query: 137 MGWTLDFLRERLLVWIQDQGGWEGLLSYFG 166 + T + E+L WI GW GL+ + G Sbjct: 149 IKTTSQYSDEKLKNWINLHDGWSGLIEFSG 178 >5TWA-A nrPDB Length = 187 Score = 45.4 bits (106), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 1/86 (1%) Query: 82 DVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTL 141 DV D+ F V F+DG +WGRV+A F+ + ++ WTL Sbjct: 96 DVTPDNVESEFREVERRTFSDG-VHWGRVIAFLAFSMSFAAYVNSRGIDGGAYSVFNWTL 154 Query: 142 DFLRERLLVWIQDQGGWEGLLSYFGT 167 L + L +IQ + GW G + Y T Sbjct: 155 RVLNDSLADFIQRENGWRGFIVYADT 180 >5UA4-A nrPDB Length = 153 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 2/73 (2%) Query: 92 FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVW 151 F V ++F D NWGR+ F++K+ K L T++ +F++ LL W Sbjct: 75 FTGVVTELFKDL-INWGRICGFIVFSAKMA-KYCKDANNHLESTVITTAYNFMKHNLLPW 132 Query: 152 IQDQGGWEGLLSY 164 + GG E L++ Sbjct: 133 MISHGGQEEFLAF 145 >4U2V-B nrPDB Length = 315 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Query: 66 IGDELDS--NMELQRMIADVD--TDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLV 121 IGD+++ + E Q M+ + ++ E F ++A +F G NWGRVVAL F +L Sbjct: 248 IGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESG-INWGRVVALLGFGYRLA 306 Query: 122 LKA 124 L Sbjct: 307 LHV 309 >1K3K-A nrPDB Length = 158 Score = 35.0 bits (79), Expect = 0.017, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Query: 102 DGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERL-LVWIQDQGGWEG 160 DGN NWGR +A+ F S + K + P L + + E + W + +GGW G Sbjct: 79 DGNMNWGRALAILTFGSFVAQK--LSNEPHLRDFALAVLPAYAYEAIGPQWFRARGGWRG 136 Query: 161 LLSY 164 L +Y Sbjct: 137 LKAY 140 >5WOS-A nrPDB Length = 148 Score = 33.1 bits (74), Expect = 0.078, Method: Compositional matrix adjust. Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 26/162 (16%) Query: 8 LGSGGPT-SSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRI 66 LGS P+ ++I T ++Q + + G+ +E K + + + R Sbjct: 3 LGSMDPSVKKDEIYYTILNIIQNYFIEYC---TGKNRNFHVEDENTYIIVKNMCDIILR- 58 Query: 67 GDELDSNMELQRMI---ADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLK 123 D+ +E ++ I +D++ + P V+ D D WGRV+++ F + V K Sbjct: 59 ----DNIVEFRKDIDRCSDIENEIPEIVY-----DTIHDK-ITWGRVISIIAFGA-YVTK 107 Query: 124 ALCTKVPELIRTIMGWTLDFLRERLLV----WIQDQGGWEGL 161 K + + +M D + E LL W+ DQ W+GL Sbjct: 108 VFKEKGRDNVVDLMP---DIITESLLSRCRSWLSDQNCWDGL 146 >5KTG-A nrPDB Length = 311 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 5/64 (7%) Query: 63 LRRIGDEL--DSNMELQRMIADVD--TDSPREVFFRVAADMFADGNFNWGRVVALFYFAS 118 L IGD++ + E Q ++ + + E+F ++A+ +F G +WGRVVAL F Sbjct: 243 LALIGDDICRRYDTEFQNLLEQLQPTAGNAYELFTKIASSLFKSG-ISWGRVVALLGFGY 301 Query: 119 KLVL 122 +L L Sbjct: 302 RLAL 305 >5TZP-A nrPDB Length = 148 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 18/77 (23%), Positives = 30/77 (38%), Gaps = 1/77 (1%) Query: 89 REVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTL-DFLRER 147 R + F V + NWGR++ + F + K P+ I+ + D + + Sbjct: 70 RNIDFNVIVTQVLEDKINWGRIITIIAFCAYYSKKVKQDTSPQYYDGIISEAITDAILSK 129 Query: 148 LLVWIQDQGGWEGLLSY 164 W DQ W G+ Y Sbjct: 130 YRSWFIDQDYWNGIRIY 146 >5VMN-A nrPDB Length = 132 Score = 31.6 bits (70), Expect = 0.22, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 6/69 (8%) Query: 92 FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLD--FLRERLL 149 + ++ +DGN NWGR++ L + K+ E RT + L+ F ++ + Sbjct: 53 ILEIGNNIVSDGNLNWGRILILLGISQLYFTKS----ESESERTQITEQLERFFRQDAIS 108 Query: 150 VWIQDQGGW 158 WI GGW Sbjct: 109 NWIASNGGW 117 >4B4S-A nrPDB Length = 175 Score = 31.6 bits (70), Expect = 0.23, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 31/81 (38%), Gaps = 18/81 (22%) Query: 106 NWGRVVALFYFASKLVLKALCTKV--------PELIRTIMGWTLD------FLRERLL-- 149 WGRVV L FA L+ + P L D L RL+ Sbjct: 85 TWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDSQRLVALLSSRLMGQ 144 Query: 150 --VWIQDQGGWEGLLSYFGTP 168 W+Q QGGW+G +F TP Sbjct: 145 HRAWLQAQGGWDGFSHFFRTP 165 >3ZCN-A nrPDB Length = 378 Score = 31.6 bits (70), Expect = 0.23, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 10/96 (10%) Query: 96 AADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQ 155 A F DGN GRV+ + Y + +L A + L R I+ D+ RLL+ + Q Sbjct: 202 AIHPFIDGNGRTGRVLNILYLIDQQLLSA---PILYLSRYIVAHKQDYY--RLLLNVTTQ 256 Query: 156 GGWEGLLSYF-----GTPTWQTVTIFVAGVLTASLT 186 W+ + + T W T I A L A T Sbjct: 257 QEWQPWIIFILNAVEQTAKWTTHKIAAARELIAHTT 292 >1DDB-A nrPDB Length = 195 Score = 28.5 bits (62), Expect = 1.8, Method: Compositional matrix adjust. Identities = 20/111 (18%), Positives = 48/111 (43%), Gaps = 9/111 (8%) Query: 52 QDASTKKLSECLRRIGDELDSNME--------LQRMIADVDTDSPREVFFRVAADMFADG 103 Q+ ++ L +IGDE+D N++ Q M + + R + ++ Sbjct: 79 QEEIIHNIARHLAQIGDEMDHNIQPTLVRQLAAQFMNGSLSEEDKRNCLAKALDEVKTAF 138 Query: 104 NFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQD 154 + A+ + L+ K + + P L+R + T++F+ + L ++++ Sbjct: 139 PRDMENDKAMLIM-TMLLAKKVASHAPSLLRDVFHTTVNFINQNLFSYVRN 188 >3Q60-A nrPDB Length = 371 Score = 28.5 bits (62), Expect = 2.1, Method: Compositional matrix adjust. Identities = 10/28 (35%), Positives = 20/28 (71%) Query: 126 CTKVPELIRTIMGWTLDFLRERLLVWIQ 153 CT +P+ ++T++G L+F R R L+ ++ Sbjct: 322 CTPLPDFVKTLIGRFLNFDRRRRLLPLE 349 >1OQP-A nrPDB Length = 77 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 31/94 (32%) Query: 9 GSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGD 68 GSG S E+I+K AF L F D +G +T++ LRR+ Sbjct: 1 GSGERDSREEILK--AFRL--FDDDNSGT-------ITIKD-------------LRRVAK 36 Query: 69 ELDSNM---ELQRMIADVDTDSPREV----FFRV 95 EL N+ ELQ MIA+ D + E+ F R+ Sbjct: 37 ELGENLTEEELQEMIAEADRNDDNEIDEDEFIRI 70 >3QRX-A nrPDB Length = 169 Score = 27.3 bits (59), Expect = 3.8, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 7/40 (17%) Query: 63 LRRIGDELDSNM---ELQRMIADVDTDSPREV----FFRV 95 LRR+ EL N+ ELQ MIA+ D + E+ F R+ Sbjct: 123 LRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRI 162 >4QUV-A nrPDB Length = 427 Score = 27.3 bits (59), Expect = 3.9, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 27/66 (40%), Gaps = 3/66 (4%) Query: 124 ALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGVL-T 182 L +P L+ + W + LV+ D W S+ PTW ++ A L Sbjct: 27 VLMIALPPLVYYL--WICVTYYQGELVFTSDAAAWRRFWSHVAPPTWHAAGLYAAWFLGQ 84 Query: 183 ASLTIW 188 A+L +W Sbjct: 85 AALQVW 90 >2GU2-A nrPDB Length = 312 Score = 26.9 bits (58), Expect = 5.9, Method: Compositional matrix adjust. Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 5/70 (7%) Query: 22 TGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNMELQRMIA 81 TG FL+ ++++ A E LE P + + + +C R I +L+ +L+ + Sbjct: 25 TGVFLVTHWLKNGA-----EVHRAGLEVKPFITNPRAVEKCTRYIDCDLNRVFDLENLSK 79 Query: 82 DVDTDSPREV 91 ++ D P EV Sbjct: 80 EMSEDLPYEV 89 >3UKM-A nrPDB Length = 280 Score = 26.6 bits (57), Expect = 7.4, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 6/87 (6%) Query: 46 TLEQPPQDASTKKLSECLRRIGDELD--SNMELQRMIADVDTDSPREVFFRVAADMFADG 103 ++E P +D ++L + RR +E + S +L++ + V S + V+ A G Sbjct: 33 SVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEASN----YGVSVLSQASG 88 Query: 104 NFNWGRVVALFYFASKLVLKALCTKVP 130 N+NW ALF+ ++ L VP Sbjct: 89 NWNWDFTSALFFASTVLSTTGYGHTVP 115 >2REK-A nrPDB Length = 199 Score = 26.2 bits (56), Expect = 8.9, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 16/32 (50%) Query: 26 LLQGFIQDRAGRMAGETPELTLEQPPQDASTK 57 LLQ Q+R ++ E L E PP A T+ Sbjct: 62 LLQAVFQERVAQLCDEARSLAAEHPPATALTR 93 >5OTJ-D nrPDB Length = 110 Score = 26.2 bits (56), Expect = 9.1, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 22/32 (68%), Gaps = 2/32 (6%) Query: 55 STKKLSECLRRIGDELDSNMELQRMIADVDTD 86 S +L++ LR +G S E+QRM+A++DTD Sbjct: 21 SLSELTDALRTLGST--SADEVQRMMAEIDTD 50 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5W62-A nrPDB 282 6e-77 5W61-A nrPDB 274 1e-74 4BD6-A nrPDB 240 2e-64 5W5Z-A nrPDB 232 6e-62 5W63-A nrPDB 220 4e-58 4IEH-A nrPDB 172 8e-44 2O2F-A nrPDB 156 8e-39 2XA0-A nrPDB 152 1e-37 5WDD-A nrPDB 151 2e-37 2W3L-A nrPDB 149 9e-37 2JCN-A nrPDB 147 4e-36 2PON-B nrPDB 144 2e-35 3ZK6-A nrPDB 143 4e-35 4WMS-A nrPDB 135 1e-32 3I1H-A nrPDB 133 5e-32 3PK1-A nrPDB 131 1e-31 4C5D-A nrPDB 130 3e-31 2BZW-A nrPDB 130 4e-31 4QNQ-A nrPDB 129 5e-31 2VOG-A nrPDB 129 6e-31 1WSX-A nrPDB 129 1e-30 2O2N-A nrPDB 129 1e-30 4QVX-A nrPDB 128 1e-30 6CKV-A nrPDB 128 1e-30 5JSB-A nrPDB 127 2e-30 3IO9-A nrPDB 126 5e-30 4CIM-A nrPDB 126 6e-30 4K5A-A nrPDB 119 8e-28 6FBX-A nrPDB 119 9e-28 4BDU-A nrPDB 115 1e-26 5TWA-A nrPDB 100 6e-22 3QBR-A nrPDB 94 5e-20 Sequences not found previously or not previously below threshold: 4U2V-B nrPDB 76 1e-14 5UA4-A nrPDB 64 6e-11 5KTG-A nrPDB 62 1e-10 4B4S-A nrPDB 54 5e-08 5WOS-A nrPDB 54 6e-08 5TZP-A nrPDB 49 1e-06 1K3K-A nrPDB 49 1e-06 2A5Y-A nrPDB 46 8e-06 5VMN-A nrPDB 45 2e-05 1TY4-A nrPDB 44 5e-05 2KUA-A nrPDB 42 1e-04 2XPX-A nrPDB 41 3e-04 1DDB-A nrPDB 34 0.040 2ESR-A nrPDB 33 0.095 4PXN-A nrPDB 30 0.67 4MI8-A nrPDB 30 0.78 5LWF-A nrPDB 29 1.8 5ABX-A nrPDB 28 2.1 4R27-A nrPDB 28 2.2 4YLT-A nrPDB 27 6.6 >5W62-A nrPDB Length = 192 Score = 282 bits (722), Expect = 6e-77, Method: Composition-based stats. Identities = 190/192 (98%), Positives = 190/192 (98%) Query: 1 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS 60 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS Sbjct: 1 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS 60 Query: 61 ECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL 120 E LRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL Sbjct: 61 ESLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL 120 Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGV 180 VLKAL TKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGV Sbjct: 121 VLKALSTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGV 180 Query: 181 LTASLTIWKKMG 192 LTASLTIWKKMG Sbjct: 181 LTASLTIWKKMG 192 >5W61-A nrPDB Length = 194 Score = 274 bits (701), Expect = 1e-74, Method: Composition-based stats. Identities = 174/192 (90%), Positives = 178/192 (92%) Query: 1 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS 60 MDGSGEQ GGPTSSEQIMKTGA LLQGFIQDRAGRM GE PEL L+ PQDASTKKLS Sbjct: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60 Query: 61 ECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL 120 E L+RIGDELDSNMELQRMIA VDTDSPREVFFRVAADMF+DGNFNWGRVVALFYFASKL Sbjct: 61 ESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120 Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGV 180 VLKAL TKVPELIRTIMGWTLDFLRERLL WIQDQGGW+GLLSYFGT TWQTVTIFVAGV Sbjct: 121 VLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTGTWQTVTIFVAGV 180 Query: 181 LTASLTIWKKMG 192 LTASLTIWKKMG Sbjct: 181 LTASLTIWKKMG 192 >4BD6-A nrPDB Length = 174 Score = 240 bits (613), Expect = 2e-64, Method: Composition-based stats. Identities = 154/171 (90%), Positives = 158/171 (92%) Query: 1 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS 60 MDGSGEQ GGPTSSEQIMKTGA LLQGFIQDRAGRM GE PEL L+ PQDASTKKLS Sbjct: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60 Query: 61 ECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL 120 E L+RIGDELDSNMELQRMIA VDTDSPREVFFRVAADMF+DGNFNWGRVVALFYFASKL Sbjct: 61 ESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120 Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQ 171 VLKAL TKVPELIRTIMGWTLDFLRERLL WIQDQGGW+GLLSYFGTPTWQ Sbjct: 121 VLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQ 171 >5W5Z-A nrPDB Length = 163 Score = 232 bits (592), Expect = 6e-62, Method: Composition-based stats. Identities = 147/161 (91%), Positives = 151/161 (93%) Query: 32 QDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNMELQRMIADVDTDSPREV 91 QDRAGRM GE PEL L+ PQDASTKKLSE L+RIGDELDSNMELQRMIA VDTDSPREV Sbjct: 1 QDRAGRMGGEAPELALDPVPQDASTKKLSESLKRIGDELDSNMELQRMIAAVDTDSPREV 60 Query: 92 FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVW 151 FFRVAADMF+DGNFNWGRVVALFYFASKLVLKAL TKVPELIRTIMGWTLDFLRERLL W Sbjct: 61 FFRVAADMFSDGNFNWGRVVALFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGW 120 Query: 152 IQDQGGWEGLLSYFGTPTWQTVTIFVAGVLTASLTIWKKMG 192 IQDQGGW+GLLSYFGT TWQTVTIFVAGVLTASLTIWKKMG Sbjct: 121 IQDQGGWDGLLSYFGTGTWQTVTIFVAGVLTASLTIWKKMG 161 >5W63-A nrPDB Length = 189 Score = 220 bits (559), Expect = 4e-58, Method: Composition-based stats. Identities = 97/185 (52%), Positives = 138/185 (74%), Gaps = 4/185 (2%) Query: 9 GSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQ----PPQDASTKKLSECLR 64 G G TS++QI++ GA LL+ FI +R R ++ + D + KKL++ L+ Sbjct: 4 GEGDGTSNDQILEVGAVLLKDFIYERVHRHGDSGTVVSRHELGGSELSDPTHKKLAQYLQ 63 Query: 65 RIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKA 124 +IGDELD+N++LQRM+AD +EVF +VA ++F+DG FNWGRVVALFYFAS+LV++A Sbjct: 64 QIGDELDNNVDLQRMLADSALQPTKEVFVKVAREIFSDGKFNWGRVVALFYFASRLVIEA 123 Query: 125 LCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWQTVTIFVAGVLTAS 184 L TK+P++IRTI+ WTLD+LRE ++ WI++QGGWEG+ +YFGTPTW+TV +F+AGVLT Sbjct: 124 LLTKIPDIIRTIINWTLDYLREHVINWIREQGGWEGIQTYFGTPTWKTVGVFLAGVLTTV 183 Query: 185 LTIWK 189 L + K Sbjct: 184 LVMRK 188 >4IEH-A nrPDB Length = 169 Score = 172 bits (436), Expect = 8e-44, Method: Composition-based stats. Identities = 45/168 (26%), Positives = 79/168 (47%), Gaps = 16/168 (9%) Query: 7 QLGSGGPTSSEQIMKTGAFLL--QGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLR 64 G G + E +MK + L +G+ D AG+ E + P+ ++ + LR Sbjct: 6 HAGRTGYDNREIVMKYIHYKLSQRGYEWD-----AGDDVEENRTEAPEGTESEVVHLTLR 60 Query: 65 RIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVALFYFAS 118 + GD+ +R A++ + + R F V ++F DG NWGR+VA F F Sbjct: 61 QAGDDFSR--RYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDG-VNWGRIVAFFEFGG 117 Query: 119 KLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFG 166 + ++++ ++ L+ I W ++L L WIQD GGW+ + +G Sbjct: 118 VMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 165 >2O2F-A nrPDB Length = 138 Score = 156 bits (393), Expect = 8e-39, Method: Composition-based stats. Identities = 45/155 (29%), Positives = 69/155 (44%), Gaps = 18/155 (11%) Query: 12 GPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELD 71 G + E +MK + L + G E LTL Q D S + RR E+ Sbjct: 1 GYDNREIVMKYIHYKL-----SQRGYEWDEVVHLTLRQAGDDFSRR-----YRRDFAEMS 50 Query: 72 SNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPE 131 S + L + R F V ++F DG NWGR+VA F F + ++++ ++ Sbjct: 51 SQLHLTPF-------TARGRFATVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSP 102 Query: 132 LIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFG 166 L+ I W ++L L WIQD GGW+ + +G Sbjct: 103 LVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 137 >2XA0-A nrPDB Length = 207 Score = 152 bits (383), Expect = 1e-37, Method: Composition-based stats. Identities = 47/204 (23%), Positives = 76/204 (37%), Gaps = 47/204 (23%) Query: 7 QLGSGGPTSSEQIMKTGAFLL--QGFIQDRAGRMA----------------GETPEL--- 45 G G + E +MK + L +G+ D A G TP Sbjct: 3 HAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAAS 62 Query: 46 ----TLEQPPQ-------------DASTKKLSECLRRIGDELDSNMELQRMIADVDTD-- 86 P Q + LR+ GD+ +R A++ + Sbjct: 63 RDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSR--RYRRDFAEMSSQLH 120 Query: 87 ----SPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLD 142 + R F V ++F DG NWGR+VA F F + ++++ ++ L+ I W + Sbjct: 121 LTPFTARGRFATVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTE 179 Query: 143 FLRERLLVWIQDQGGWEGLLSYFG 166 +L L WIQD GGW+ + +G Sbjct: 180 YLNRHLHTWIQDNGGWDAFVELYG 203 >5WDD-A nrPDB Length = 168 Score = 151 bits (382), Expect = 2e-37, Method: Composition-based stats. Identities = 41/163 (25%), Positives = 74/163 (45%), Gaps = 8/163 (4%) Query: 8 LGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIG 67 LGS + ++++ L + +I R R + P ++S L R+G Sbjct: 3 LGSDRSPTDKELVSQAKALCRDYINSRLIRAGVSWSKPEHNTPVPGGKLAEVSAILLRLG 62 Query: 68 DELD-------SNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKL 120 DEL+ N+ Q I+ + F VAA +F G WG+VV+L+ A+ L Sbjct: 63 DELEYIRPNVYRNIARQLNISLHSETVVTDAFLAVAAQIFTAG-ITWGKVVSLYAVAAGL 121 Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLS 163 + + P ++ TI+ +F+R+ L+ W++ +GGW + Sbjct: 122 AVDCVRHAQPAMVHTIVDCLGEFVRKTLVTWLKRRGGWADITK 164 >2W3L-A nrPDB Length = 144 Score = 149 bits (375), Expect = 9e-37, Method: Composition-based stats. Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 13/154 (8%) Query: 13 PTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDS 72 + E +MK + L + E TL + D S + RR E+ S Sbjct: 1 YDNREIVMKYIHYKLSQRGYEWDAGADSEVVHKTLREAGDDFSRR-----YRRDFAEMSS 55 Query: 73 NMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPEL 132 + L + R F V ++F DG NWGR+VA F F + ++++ ++ L Sbjct: 56 GLHLTPF-------TARGRFATVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSPL 107 Query: 133 IRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFG 166 + I W ++L L WIQD GGW+ + +G Sbjct: 108 VDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 141 >2JCN-A nrPDB Length = 172 Score = 147 bits (370), Expect = 4e-36, Method: Composition-based stats. Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 10/173 (5%) Query: 1 MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLS 60 M S EQ+ +E++ ++ F Q+ G A PE+ ++ ++ Sbjct: 2 MSASEEQVAQ----DTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVG 57 Query: 61 ECLRRIGDELDS--NMELQRMIADVDT--DSPREVFFRVAADMFADGNFNWGRVVALFYF 116 L IGD+++ + E Q M+ + ++ E F ++A +F G NWGRVVAL F Sbjct: 58 RQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESG-INWGRVVALLGF 116 Query: 117 ASKLVLKALCTKVPELIRTIMGWTLDFLRERLLV-WIQDQGGWEGLLSYFGTP 168 +L L + + + + +DF+ + WI +GGW L+ P Sbjct: 117 GYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWVAALNLGNGP 169 >2PON-B nrPDB Length = 156 Score = 144 bits (363), Expect = 2e-35, Method: Composition-based stats. Identities = 38/161 (23%), Positives = 78/161 (48%), Gaps = 16/161 (9%) Query: 14 TSSEQIMKTGAFLL--QGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELD 71 ++ E ++ ++ L +G+ + E + P+ ++ + + LR GDE + Sbjct: 4 SNRELVVDFLSYKLSQKGYSWSQF-----SDVEENRTEAPEGTESEAVKQALREAGDEFE 58 Query: 72 SNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKAL 125 + +R +D+ + + + F +V ++F DG NWGR+VA F F L ++++ Sbjct: 59 --LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVAFFSFGGALCVESV 115 Query: 126 CTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFG 166 ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 116 DKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 156 >3ZK6-A nrPDB Length = 181 Score = 143 bits (361), Expect = 4e-35, Method: Composition-based stats. Identities = 38/162 (23%), Positives = 76/162 (46%), Gaps = 16/162 (9%) Query: 14 TSSEQIMKTGAFLL--QGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELD 71 ++ E ++ ++ L +G+ + E + P+ + + LR GDE + Sbjct: 8 SNRELVVDFLSYKLSQKGYSWSQF-----SDVEENRTEAPEGIPMAAVKQALREAGDEFE 62 Query: 72 SNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKAL 125 + +R +D+ + + + F +V ++F DG NWGR+VA F F L ++++ Sbjct: 63 --LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVAFFSFGGALCVESV 119 Query: 126 CTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGT 167 ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 120 DKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN 161 >4WMS-A nrPDB Length = 518 Score = 135 bits (339), Expect = 1e-32, Method: Composition-based stats. Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 9/152 (5%) Query: 18 QIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNME-- 75 ++ + ++ +++++A A P A+++K E LRR+GD + N E Sbjct: 370 ELYRQSLEIISRYLREQATGAADTAP-----MGASGATSRKALETLRRVGDGVQRNHETA 424 Query: 76 LQRMIADVDTDSPREV--FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELI 133 Q M+ +D + +V RV +F+DG NWGR+V L F + + I Sbjct: 425 FQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCI 484 Query: 134 RTIMGWTLDFLRERLLVWIQDQGGWEGLLSYF 165 + D L W+ Q GW+G + +F Sbjct: 485 EPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 516 >3I1H-A nrPDB Length = 161 Score = 133 bits (334), Expect = 5e-32, Method: Composition-based stats. Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 9/138 (6%) Query: 37 RMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNME--LQRMIADV---DTDSPREV 91 R+A + + L+ P + K S L+ + + +E L+ + +V D+ R + Sbjct: 21 RLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTL 80 Query: 92 FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRT---IMGWTLDFLRERL 148 F +V F DG NWGR+V +F F L+ K L ++ + T I + +F+ Sbjct: 81 FNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNT 140 Query: 149 LVWIQDQGGWE-GLLSYF 165 WI+ GGWE G + F Sbjct: 141 GEWIRQNGGWENGFVKKF 158 >3PK1-A nrPDB Length = 189 Score = 131 bits (330), Expect = 1e-31, Method: Composition-based stats. Identities = 42/160 (26%), Positives = 65/160 (40%), Gaps = 6/160 (3%) Query: 12 GPTSSEQIMKTGAFLLQG--FIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDE 69 G ++ M L + I R R + T A+++K E LRR+GD Sbjct: 23 GTDDDDKAMADIGSLYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDG 82 Query: 70 LDSNME--LQRMIADVDTDSPREV--FFRVAADMFADGNFNWGRVVALFYFASKLVLKAL 125 + N E Q M+ +D + +V RV +F+DG NWGR+V L F + + Sbjct: 83 VQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLK 142 Query: 126 CTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYF 165 I + D L W+ Q GW+G + +F Sbjct: 143 TINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 182 >4C5D-A nrPDB Length = 158 Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats. Identities = 38/166 (22%), Positives = 73/166 (43%), Gaps = 28/166 (16%) Query: 8 LGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIG 67 LGS ++ E ++ ++ L ++ + + LR G Sbjct: 3 LGSMSQSNRELVVDFLSYKLSQ--------KGYSWSQMA-----------AVKQALREAG 43 Query: 68 DELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVALFYFASKLV 121 DE + + +R +D+ + + + F +V ++F DG NWGR+VA F F L Sbjct: 44 DEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVAFFSFGGALC 100 Query: 122 LKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGT 167 ++++ ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 101 VESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN 146 >2BZW-A nrPDB Length = 211 Score = 130 bits (326), Expect = 4e-31, Method: Composition-based stats. Identities = 33/117 (28%), Positives = 60/117 (51%), Gaps = 9/117 (7%) Query: 57 KKLSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRV 110 + + LR GDE + + +R +D+ + + + F +V ++F DG NWGR+ Sbjct: 84 AAVKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRI 140 Query: 111 VALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGT 167 VA F F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 141 VAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGN 197 >4QNQ-A nrPDB Length = 240 Score = 129 bits (325), Expect = 5e-31, Method: Composition-based stats. Identities = 42/153 (27%), Positives = 70/153 (45%), Gaps = 23/153 (15%) Query: 57 KKLSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRV 110 + + LR GDE + + +R +D+ + + + F +V ++F DG NWGR+ Sbjct: 91 AAVKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRI 147 Query: 111 VALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPT- 169 VA F F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 148 VAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAA 207 Query: 170 ------------WQTVTIFVAG-VLTASLTIWK 189 W + VAG VL SL K Sbjct: 208 AESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 240 >2VOG-A nrPDB Length = 157 Score = 129 bits (325), Expect = 6e-31, Method: Composition-based stats. Identities = 32/139 (23%), Positives = 61/139 (43%), Gaps = 9/139 (6%) Query: 36 GRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNME--LQRMIADV---DTDSPRE 90 +A + L+ P +++ + L+R+ + +E L+ + D D+ R Sbjct: 15 HSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARI 74 Query: 91 VFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVP---ELIRTIMGWTLDFLRER 147 +F +V F DG NWGR+V +F F L+ K ++ + + + +F+ Sbjct: 75 IFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLKQEQIALDVSAYKQVSSFVAEFIMNN 134 Query: 148 LLVWIQDQGGW-EGLLSYF 165 WI+ GGW +G + F Sbjct: 135 TGEWIRQNGGWEDGFIKKF 153 >1WSX-A nrPDB Length = 162 Score = 129 bits (323), Expect = 1e-30, Method: Composition-based stats. Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 4/139 (2%) Query: 31 IQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNME--LQRMIADVDTDSP 88 I R R + + A+ ++ E LRR+GD + N E Q M+ +D + Sbjct: 16 IISRYLREQATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNE 75 Query: 89 REV--FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRE 146 +V F RV +F DG NWGR+V L F + + I + D L Sbjct: 76 GDVKSFSRVMVHVFKDGVTNWGRIVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVR 135 Query: 147 RLLVWIQDQGGWEGLLSYF 165 W+ Q GW+G + +F Sbjct: 136 TKRDWLVKQRGWDGFVEFF 154 >2O2N-A nrPDB Length = 145 Score = 129 bits (323), Expect = 1e-30, Method: Composition-based stats. Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 9/116 (7%) Query: 57 KKLSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRV 110 + + LR GDE + + +R +D+ + + + F +V ++F DG NWGR+ Sbjct: 33 AAVKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRI 89 Query: 111 VALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFG 166 VA F F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 90 VAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 145 >4QVX-A nrPDB Length = 167 Score = 128 bits (322), Expect = 1e-30, Method: Composition-based stats. Identities = 34/117 (29%), Positives = 59/117 (50%), Gaps = 9/117 (7%) Query: 57 KKLSECLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRV 110 + + LR GDE + + +R +D+ + + + F +V ++F DG NWGR+ Sbjct: 34 AAVKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRI 90 Query: 111 VALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGT 167 VA F F L ++++ K+ L+ I W +L + L WIQ+ GGW + +G Sbjct: 91 VAFFSFGGALCVESVDKKMQVLVSRIAAWMATYLNDHLEPWIQENGGWATFVELYGN 147 >6CKV-A nrPDB Length = 158 Score = 128 bits (321), Expect = 1e-30, Method: Composition-based stats. Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 10/158 (6%) Query: 13 PTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELD- 71 PT E + + A L + ++ R R P +++ L R+GDEL+ Sbjct: 3 PTDKELVAQAKA-LGREYVHARLLRAGLSWSAPE-RAAPVPGRLAEVAAVLLRLGDELEM 60 Query: 72 ------SNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKAL 125 N+ Q I+ + F VA +F+ G WG+VV+L+ A+ L + A+ Sbjct: 61 IRPSVYRNVARQLHISLQSERVVTDAFLAVAGHIFSAG-ITWGKVVSLYAVAAGLAVDAV 119 Query: 126 CTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLS 163 P ++ ++ +F+R+ L W++ +GGW +L Sbjct: 120 RQAQPAMVHALVDALGEFVRKTLATWLRRRGGWTDVLK 157 >5JSB-A nrPDB Length = 179 Score = 127 bits (320), Expect = 2e-30, Method: Composition-based stats. Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 4/139 (2%) Query: 31 IQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNME--LQRMIADVDTDSP 88 I R R + T A+++K E LRR+GD + N E Q M+ +D + Sbjct: 10 IISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNE 69 Query: 89 REV--FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRE 146 +V RV +F+DG NWGR+V L F + + I + D L Sbjct: 70 DDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR 129 Query: 147 RLLVWIQDQGGWEGLLSYF 165 W+ Q GW+G + +F Sbjct: 130 TKRDWLVKQRGWDGFVEFF 148 >3IO9-A nrPDB Length = 162 Score = 126 bits (317), Expect = 5e-30, Method: Composition-based stats. Identities = 37/139 (26%), Positives = 58/139 (41%), Gaps = 4/139 (2%) Query: 31 IQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNME--LQRMIADVDTDSP 88 I R R + + A+ ++ E LRR+GD + N E Q M+ +D + Sbjct: 16 IISRYLREQATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNE 75 Query: 89 REV--FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRE 146 +V RV +F+DG NWGR+V L F + + I + D L Sbjct: 76 DDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR 135 Query: 147 RLLVWIQDQGGWEGLLSYF 165 W+ Q GW+G + +F Sbjct: 136 TKRDWLVKQRGWDGFVEFF 154 >4CIM-A nrPDB Length = 163 Score = 126 bits (316), Expect = 6e-30, Method: Composition-based stats. Identities = 40/162 (24%), Positives = 74/162 (45%), Gaps = 21/162 (12%) Query: 13 PTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDS 72 P + + + L+ + G ++G P + + L + LR IGDE ++ Sbjct: 8 PDTRALVADFVGYKLR-----QKGYVSGAG-------PGEGPAADPLGQALRAIGDEFET 55 Query: 73 NMELQRMIAD------VDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALC 126 +R +D V S ++ F +V+ ++F G NWGR+VA F F + L +++ Sbjct: 56 --RFRRTFSDLAAQLHVTPGSAQQRFTQVSDELF-QGGPNWGRLVAFFVFGAALCAESVN 112 Query: 127 TKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTP 168 ++ L+ + W +++L RL WI GGW + +G Sbjct: 113 KEMEPLVGQVQEWMVEYLETRLADWIHSSGGWAEFTALYGDG 154 >4K5A-A nrPDB Length = 184 Score = 119 bits (298), Expect = 8e-28, Method: Composition-based stats. Identities = 38/162 (23%), Positives = 71/162 (43%), Gaps = 21/162 (12%) Query: 13 PTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDS 72 P + + + L+ + G + G P + + L + +R GDE ++ Sbjct: 19 PDTRALVADFVGYKLR-----QKGYVCGAG-------PGEGPAADPLHQAMRAAGDEFET 66 Query: 73 NMELQRMIAD------VDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALC 126 +R +D V S ++ F +V+ ++F G NWGR+VA F F + L +++ Sbjct: 67 --RFRRTFSDLAAQLHVTPGSAQQRFTQVSDELF-QGGPNWGRLVAFFVFGAALCAESVN 123 Query: 127 TKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTP 168 ++ L+ + W + +L RL WI GGW + +G Sbjct: 124 KEMEVLVGQVQEWMVAYLETRLADWIHSSGGWAEFTALYGDG 165 >6FBX-A nrPDB Length = 152 Score = 119 bits (297), Expect = 9e-28, Method: Composition-based stats. Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 6/122 (4%) Query: 52 QDASTKKLSECLRRIGDELDSNME-----LQRMIADVDTDSPREVFFRVAADMFADGNFN 106 Q + +E +R + E++ L + D P + V ++ DG N Sbjct: 28 QQTPPSESAEAMRYLAKEMEQQHRTKFRSLSQEFLDTCGADPSKCLQSVMRELVGDGKMN 87 Query: 107 WGRVVALFYFASKLVLKALCT-KVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYF 165 WGRVV++F F L + L + E R + D+L W+ + GGWEG +F Sbjct: 88 WGRVVSIFTFTGVLASELLSRGENSEGSRRLAETIADYLGGEKQDWLVENGGWEGFCRFF 147 Query: 166 GT 167 Sbjct: 148 HN 149 >4BDU-A nrPDB Length = 311 Score = 115 bits (287), Expect = 1e-26, Method: Composition-based stats. Identities = 71/78 (91%), Positives = 73/78 (93%) Query: 51 PQDASTKKLSECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRV 110 DASTKKLSE L+RIGDELDSNMELQRMIA VDTDSPREVFFRVAADMF+DGNFNWGRV Sbjct: 234 GSDASTKKLSESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRV 293 Query: 111 VALFYFASKLVLKALCTK 128 VALFYFASKLVLKAL TK Sbjct: 294 VALFYFASKLVLKALSTK 311 >5TWA-A nrPDB Length = 187 Score = 99.9 bits (247), Expect = 6e-22, Method: Composition-based stats. Identities = 32/131 (24%), Positives = 53/131 (40%), Gaps = 2/131 (1%) Query: 38 MAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNME-LQRMIADVDTDSPREVFFRVA 96 A + + DA+ + + G ++ N+ +R DV D+ F V Sbjct: 51 AASDGLSEEERRTAADAAERMTAVIAGTPGIAVERNVRDFRRGGWDVTPDNVESEFREVE 110 Query: 97 ADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQG 156 F+DG +WGRV+A F+ + ++ WTL L + L +IQ + Sbjct: 111 RRTFSDG-VHWGRVIAFLAFSMSFAAYVNSRGIDGGAYSVFNWTLRVLNDSLADFIQREN 169 Query: 157 GWEGLLSYFGT 167 GW G + Y T Sbjct: 170 GWRGFIVYADT 180 >3QBR-A nrPDB Length = 179 Score = 93.7 bits (231), Expect = 5e-20, Method: Composition-based stats. Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 13/125 (10%) Query: 53 DASTKKLSECLRRIGD---ELDSNMELQRMIADVDTD-------SPREVFF-RVAADMFA 101 + + L+ +GD E++ + + D + E+F+ + +F Sbjct: 56 PNGQEIIHSLLQLVGDFNQRFSQTHEIEPVAQSLGIDSDKPVDKTALEIFYLEILNGLFE 115 Query: 102 DGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGL 161 NWGR+VA+F F LVL+ + I+ ++ T + E+L WI GW GL Sbjct: 116 --KLNWGRIVAMFAFLRILVLRLSKHGHSDAIQMLIKTTSQYSDEKLKNWINLHDGWSGL 173 Query: 162 LSYFG 166 + + G Sbjct: 174 IEFSG 178 >4U2V-B nrPDB Length = 315 Score = 76.0 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 5/81 (6%) Query: 54 ASTKKLSECLRRIGDELDS--NMELQRMIADVDT--DSPREVFFRVAADMFADGNFNWGR 109 ++ ++ L IGD+++ + E Q M+ + ++ E F ++A +F G NWGR Sbjct: 236 STMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESG-INWGR 294 Query: 110 VVALFYFASKLVLKALCTKVP 130 VVAL F +L L + Sbjct: 295 VVALLGFGYRLALHVYQHGLT 315 >5UA4-A nrPDB Length = 153 Score = 63.6 bits (153), Expect = 6e-11, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 73 NMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPEL 132 N ++ + + F V ++F D NWGR+ F++K+ L Sbjct: 56 NKQVTITFSLTSVQEIKTQFTGVVTELFKD-LINWGRICGFIVFSAKMAKYCKD-ANNHL 113 Query: 133 IRTIMGWTLDFLRERLLVWIQDQGGWEGLLSY 164 T++ +F++ LL W+ GG E L++ Sbjct: 114 ESTVITTAYNFMKHNLLPWMISHGGQEEFLAF 145 >5KTG-A nrPDB Length = 311 Score = 62.1 bits (149), Expect = 1e-10, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 5/82 (6%) Query: 51 PQDASTKKLSECLRRIGDELDS--NMELQRMIADVDT--DSPREVFFRVAADMFADGNFN 106 ++ ++ L IGD++ + E Q ++ + + E+F ++A+ +F G + Sbjct: 231 GSNSILGQVGRQLALIGDDICRRYDTEFQNLLEQLQPTAGNAYELFTKIASSLFKSG-IS 289 Query: 107 WGRVVALFYFASKLVLKALCTK 128 WGRVVAL F +L L Sbjct: 290 WGRVVALLGFGYRLALYVYQRG 311 >4B4S-A nrPDB Length = 175 Score = 53.6 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 35/164 (21%), Positives = 58/164 (35%), Gaps = 27/164 (16%) Query: 29 GFIQDRAGRMAGETPELTLEQP--PQDASTKKLSECLRRIGDELDSNMELQRMIADVDTD 86 +++R + + + +P P+ A + + LR L R Sbjct: 5 DPLRERTELLLADYLGYSAREPGTPEPAPSTPEAAVLRSAAARLRQIH---RSFFSAYLG 61 Query: 87 SPREVFFRVA---ADMFADG-NFNWGRVVALFYFASKLVLKA---------------LCT 127 P F VA + +D WGRVV L FA L+ + L Sbjct: 62 YPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKE 121 Query: 128 KVPELIR---TIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTP 168 + ++ R ++ L + W+Q QGGW+G +F TP Sbjct: 122 QEGDVARDSQRLVALLSSRLMGQHRAWLQAQGGWDGFSHFFRTP 165 >5WOS-A nrPDB Length = 148 Score = 53.6 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 39/91 (42%), Gaps = 3/91 (3%) Query: 71 DSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVP 130 D+ +E ++ I D +D E+ + D D WGRV+++ F + + Sbjct: 59 DNIVEFRKDI-DRCSDIENEI-PEIVYDTIHD-KITWGRVISIIAFGAYVTKVFKEKGRD 115 Query: 131 ELIRTIMGWTLDFLRERLLVWIQDQGGWEGL 161 ++ + + L R W+ DQ W+GL Sbjct: 116 NVVDLMPDIITESLLSRCRSWLSDQNCWDGL 146 >5TZP-A nrPDB Length = 148 Score = 49.4 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 28/74 (37%), Gaps = 2/74 (2%) Query: 92 FFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIM-GWTLDFLRERLLV 150 F + + D NWGR++ + F + K P+ I+ D + + Sbjct: 74 FNVIVTQVLED-KINWGRIITIIAFCAYYSKKVKQDTSPQYYDGIISEAITDAILSKYRS 132 Query: 151 WIQDQGGWEGLLSY 164 W DQ W G+ Y Sbjct: 133 WFIDQDYWNGIRIY 146 >1K3K-A nrPDB Length = 158 Score = 49.0 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%) Query: 71 DSNMELQRMIADV--DTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTK 128 D + M+A+V + + + + DGN NWGR +A+ F S + K Sbjct: 46 DKESLFEAMLANVRFHSTTGIDQLGLSMLQVSGDGNMNWGRALAILTFGSFVAQKLSNE- 104 Query: 129 VPELIRTIMGWTLDFLRERLLV-WIQDQGGWEGLLSY 164 P L + + E + W + +GGW GL +Y Sbjct: 105 -PHLRDFALAVLPAYAYEAIGPQWFRARGGWRGLKAY 140 >2A5Y-A nrPDB Length = 204 Score = 46.3 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 20/127 (15%), Positives = 45/127 (35%), Gaps = 10/127 (7%) Query: 49 QPPQDASTKKLSECLRRIGDELDSNM-ELQRMIADVDTDSPREVFF-------RVAADMF 100 P + + E +R +G + E ++ PR F V Sbjct: 55 APGLPSGVQPEHEMMRVMGTIFEKKHAENFETFSEQLLAVPRISFSLYQDVVRTVGNAQT 114 Query: 101 ADGNFNWGRVVALFYFASKLVLKAL-CTKVPELIRTIMGWTLDFLRERLL-VWIQDQGGW 158 ++GR++ L F + K + ++ +R + +T F++ R+ W + W Sbjct: 115 DQSPMSYGRLIGLISFGGFVAAKMMESVELQGQVRNLFVYTSLFIKTRIRNNWKEHNRSW 174 Query: 159 EGLLSYF 165 + ++ Sbjct: 175 DDFMTLG 181 >5VMN-A nrPDB Length = 132 Score = 44.8 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 27/67 (40%), Gaps = 4/67 (5%) Query: 93 FRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLR-ERLLVW 151 + ++ +DGN NWGR++ L L ++ I F R + + W Sbjct: 54 LEIGNNIVSDGNLNWGRILILL---GISQLYFTKSESESERTQITEQLERFFRQDAISNW 110 Query: 152 IQDQGGW 158 I GGW Sbjct: 111 IASNGGW 117 >1TY4-A nrPDB Length = 170 Score = 43.6 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 18/127 (14%), Positives = 44/127 (34%), Gaps = 10/127 (7%) Query: 49 QPPQDASTKKLSECLRRIGDELDSNM--------ELQRMIADVDTDSPREVFFRVAADMF 100 P + E +R +G + E + + ++V V Sbjct: 35 APGLPCGVQPEHEMMRVMGTIFEKKHAENFETFCEQLLAVPRISFSPYQDVVRTVGNAQT 94 Query: 101 ADGNFNWGRVVALFYFASKLVLKAL-CTKVPELIRTIMGWTLDFLRERLL-VWIQDQGGW 158 ++GR++ L F + K + ++ +R + +T F++ R+ W + W Sbjct: 95 DQCPMSYGRLIGLISFGGFVAAKMMESVELQGQVRNLFVYTSLFIKTRIRNNWKEHNRSW 154 Query: 159 EGLLSYF 165 + ++ Sbjct: 155 DDFMTLG 161 >2KUA-A nrPDB Length = 170 Score = 42.5 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 57/159 (35%), Gaps = 20/159 (12%) Query: 28 QGFIQDRAGRMAGETPELTLEQPPQDASTKKLSEC--LRRIGDELDSNMELQRMIADVDT 85 Q + +R R+ + +P E LR + ++ Q + Sbjct: 10 QDPLHERTRRLLSDYIFFCAREPDTPEPPPTSVEAALLRSVTRQIQQEH--QEFFSSFCE 67 Query: 86 --DSPREVFFRVAADMFA-DGNFNWGRVVALFYFASKL--------VLKALCTKVPELIR 134 + E+ ++A + + D +F+W ++V L FA L V + ++ Sbjct: 68 SRGNRLELVKQMADKLLSKDQDFSWSQLVMLLAFAGTLMNQGPYMAVKQKRDLGNRVIVT 127 Query: 135 T----IMGWTLDFLR-ERLLVWIQDQGGWEGLLSYFGTP 168 I+ + + L R ++ GGW+G +F P Sbjct: 128 RDCCLIVNFLYNLLMGRRHRARLEALGGWDGFCRFFKNP 166 >2XPX-A nrPDB Length = 173 Score = 41.3 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 45/130 (34%), Gaps = 19/130 (14%) Query: 44 ELTLEQPPQDASTKKLSECLRRIGDELDSNME--------LQRMIADVDTDSPREVFFRV 95 E L P+D + L I ++ N E VD D F V Sbjct: 48 ETPLRLSPEDTVVLRYHVLLEEI---IERNSETFTETWNRFITHTEHVDLD-----FNSV 99 Query: 96 AADMFADGNFNWGRVVALFYFASKLVLKALCTKVPE--LIRTIMGWTLDFLRERLLVWIQ 153 ++F G+ + GR +A + C + ++ + L+ E L WI Sbjct: 100 FLEIFHRGDPSLGRALAWMAWCMHACRTLCCNQSTPYYVVDLSVRGMLE-ASEGLDGWIH 158 Query: 154 DQGGWEGLLS 163 QGGW L+ Sbjct: 159 QQGGWSTLIE 168 >1DDB-A nrPDB Length = 195 Score = 34.0 bits (76), Expect = 0.040, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 39/103 (37%), Gaps = 9/103 (8%) Query: 59 LSECLRRIGDELD--------SNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRV 110 ++ L +IGDE+D + Q M + + R + ++ + Sbjct: 86 IARHLAQIGDEMDHNIQPTLVRQLAAQFMNGSLSEEDKRNCLAKALDEVKTAFPRDMEND 145 Query: 111 VALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQ 153 A+ L K P L+R + T++F+ + L +++ Sbjct: 146 KAMLIMTMLLAKKVASHA-PSLLRDVFHTTVNFINQNLFSYVR 187 >2ESR-A nrPDB Length = 177 Score = 32.8 bits (73), Expect = 0.095, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%), Gaps = 5/50 (10%) Query: 84 DTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELI 133 +D R F + F N GRV+ LF + L ++A+ + + Sbjct: 14 TSDKVRGAIFNMIGPYF-----NGGRVLDLFAGSGGLAIEAVSRGMSAAV 58 >4PXN-A nrPDB Length = 525 Score = 30.1 bits (66), Expect = 0.67, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 7/73 (9%) Query: 3 GSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSEC 62 GSG + S PT+++ I + + + + R + + + P K E Sbjct: 48 GSGPTVTSTSPTNNQVIAEVVEASVHDYEEG--MRACFDAAKTWMAIPAP-----KRGEI 100 Query: 63 LRRIGDELDSNME 75 +R+IGD L + + Sbjct: 101 VRQIGDALRAKLH 113 >4MI8-A nrPDB Length = 143 Score = 29.7 bits (65), Expect = 0.78, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 29/96 (30%), Gaps = 9/96 (9%) Query: 60 SECLRRIGDELDSNMELQRMIADV-------DTDSPREVFFRVAADMFADGNFNWGRVVA 112 S L + + E +R V + + ++ +F D N GR+V Sbjct: 33 SAVLVDVSKIITLTQEFRRHYDSVYRADYGPALKNWKRDLSKLFTSLFVD-VINSGRIVG 91 Query: 113 LFYFASKLVLKALCTKV-PELIRTIMGWTLDFLRER 147 F + + LC E + F E Sbjct: 92 FFDVGRYVCEEVLCPGSWTEDHELLNDCMTHFFIEN 127 >5LWF-A nrPDB Length = 273 Score = 28.6 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 37/109 (33%), Gaps = 22/109 (20%) Query: 54 ASTKKLSECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVAL 113 + L + LR+IGDE+ + + + +V+ ++ A + V +L Sbjct: 114 GGPESLKKELRKIGDEVTNPERFEPELNEVNPGETQD--TSTARAL----------VTSL 161 Query: 114 FYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQG---GWE 159 F L+ E ++ W R + G GWE Sbjct: 162 RAF----ALEDPGKLPSEKRELLIDWMK---RNTTGDALIRAGVPDGWE 203 >5ABX-A nrPDB Length = 190 Score = 28.2 bits (61), Expect = 2.1, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 16/38 (42%) Query: 71 DSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWG 108 D N E + + V E F+ + + + G NWG Sbjct: 21 DRNKEWEDCLKMVSLFDTVEDFWSLYNHIQSAGGLNWG 58 >4R27-A nrPDB Length = 434 Score = 28.2 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 27/94 (28%), Gaps = 10/94 (10%) Query: 67 GDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALC 126 GD +D + IA + F V W R+ S L Sbjct: 47 GDAVDHYHRYREDIALIAGLGFTSYRFSVE----------WARIEPEEGHFSVAALDHYK 96 Query: 127 TKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEG 160 + + + F +W+ GGWEG Sbjct: 97 RVLEACREHGLTPVVTFHHFASPLWLLRSGGWEG 130 >4YLT-A nrPDB Length = 316 Score = 26.7 bits (57), Expect = 6.6, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 25/72 (34%), Gaps = 4/72 (5%) Query: 49 QPPQDASTKKLSECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWG 108 P A+ + +S +++G +D + + S F + DG G Sbjct: 240 LVPHQANLRIISATAKKLGMGMDKVVITLDRHGNTSAASVPSAF----DEAVRDGRIQRG 295 Query: 109 RVVALFYFASKL 120 ++V L F Sbjct: 296 QLVLLEAFGGGF 307 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.125 0.341 Lambda K H 0.267 0.0390 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,492,952 Number of Sequences: 36641 Number of extensions: 222580 Number of successful extensions: 776 Number of sequences better than 10.0: 55 Number of HSP's better than 10.0 without gapping: 85 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 617 Number of HSP's gapped (non-prelim): 117 length of query: 192 length of database: 10,336,785 effective HSP length: 92 effective length of query: 100 effective length of database: 6,965,813 effective search space: 696581300 effective search space used: 696581300 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 56 (26.3 bits)