BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q07523 (353 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3SGZ-A nrPDB 716 0.0 2RDU-A nrPDB 327 4e-90 1AL8-A nrPDB 298 2e-81 5ZBN-A nrPDB 296 1e-80 1QCW-A nrPDB 247 5e-66 1SZG-A nrPDB 245 2e-65 2A85-A nrPDB 222 2e-58 2CDH-0 nrPDB 211 4e-55 6BFG-A nrPDB 207 4e-54 2J6X-A nrPDB 206 1e-53 6DVI-A nrPDB 193 1e-49 3SR7-A nrPDB 47 9e-06 1P0K-A nrPDB 46 3e-05 4N02-A nrPDB 41 8e-04 2ZRW-A nrPDB 40 0.001 1UUO-A nrPDB 35 0.043 5AHL-A nrPDB 34 0.075 4DQW-A nrPDB 34 0.077 4FEZ-A nrPDB 33 0.16 4FXS-A nrPDB 33 0.16 3TSB-A nrPDB 32 0.28 1VRD-A nrPDB 32 0.28 3FFS-A nrPDB 32 0.32 1JUE-A nrPDB 32 0.34 4MJM-A nrPDB 32 0.36 1JCN-A nrPDB 32 0.37 3U2O-A nrPDB 32 0.45 3R2G-A nrPDB 32 0.54 4QJ1-A nrPDB 32 0.61 2CU0-A nrPDB 31 0.70 5UQG-A nrPDB 31 0.85 1EEP-A nrPDB 31 0.99 5UPU-A nrPDB 31 1.00 1ZFJ-A nrPDB 30 1.2 1KAE-A nrPDB 30 1.5 5LSM-A nrPDB 30 1.7 2JS7-A nrPDB 30 1.9 1YPF-A nrPDB 30 2.3 6I0M-A nrPDB 29 3.7 4JDY-A nrPDB 28 4.2 4Q4K-A nrPDB 28 4.9 5CSS-A nrPDB 28 5.6 1HG3-A nrPDB 28 6.3 2ISS-A nrPDB 28 6.6 6I4B-A nrPDB 28 7.2 2ZCW-A nrPDB 28 8.2 1EUF-A nrPDB 27 9.5 >3SGZ-A nrPDB Length = 352 Score = 716 bits (1848), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/352 (98%), Positives = 348/352 (98%) Query: 2 PLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTR 61 PLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTR Sbjct: 1 PLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTR 60 Query: 62 TTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAP 121 TTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAP Sbjct: 61 TTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAP 120 Query: 122 EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILL 181 EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANIL Sbjct: 121 EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILK 180 Query: 182 KDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQ 241 LRALKEEKPTQSVPV FPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQ Sbjct: 181 AALRALKEEKPTQSVPVLFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQ 240 Query: 242 GIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFL 301 GIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFL Sbjct: 241 GIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFL 300 Query: 302 GRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL 353 GRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL Sbjct: 301 GRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL 352 >2RDU-A nrPDB Length = 387 Score = 327 bits (838), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 159/357 (44%), Positives = 231/357 (64%), Gaps = 10/357 (2%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 L+C+ D++ HA+ L K+ +D+ A+D T ++NIAAF R +L PR LR++++ D T Sbjct: 22 LICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLST 81 Query: 63 TIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPE 122 ++ GQ +S PIC+ TA +A DGE +T RA Q ++SS+A+ S+E++ A PE Sbjct: 82 SVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPE 141 Query: 123 GFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLK 182 RW QLY+ D + K++V++AE +G+KA+ +T+DTP LGNR D RN+ L + +K Sbjct: 142 ALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMK 201 Query: 183 DLRA----------LKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDA 232 + ++ + S W D+ L+ +T LPI+ KGIL +DA Sbjct: 202 NFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDA 261 Query: 233 ELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKAL 292 A+KH + GI+VSNHG RQLD V A+ID L E+V AV+GK+EV++DGGVR GTDVLKAL Sbjct: 262 REAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKAL 321 Query: 293 ALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQ 349 ALGA+ +F+GRPI+WGLA +GE GV++VL+IL E M LSGCQ+V I L++ Sbjct: 322 ALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVR 378 >1AL8-A nrPDB Length = 359 Score = 298 bits (763), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 162/351 (46%), Positives = 230/351 (65%), Gaps = 8/351 (2%) Query: 1 MPLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDT 60 M + + +++A A+++L K +D+ A+D T +EN AF RI RPR L D++ +D Sbjct: 1 MEITNVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDM 60 Query: 61 RTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAA 120 TTI G +IS PI I+PTA +A P+GE +TARAA A +SS+A+ S+E++ + Sbjct: 61 TTTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTG 120 Query: 121 PEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANIL 180 P G R+FQLY+ D + Q+V+RAE GFKA+ +T+DTP LG R D +N+ L + Sbjct: 121 P-GIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLT 179 Query: 181 LKDLRAL---KEEKPTQSVPVSFPKA----SFCWNDLSLLQSITRLPIILKGILTKEDAE 233 LK+ + K +K S S+ S W D++ LQ+IT LPI++KG++T EDA Sbjct: 180 LKNFEGIDLGKMDKANDSGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDAR 239 Query: 234 LAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALA 293 LA++H GI+VSNHG RQLD V A+I AL EVV A +G+I V++DGGVR GTDV KALA Sbjct: 240 LAVQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALA 299 Query: 294 LGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEIS 344 LGA +F+GRP+++ LA +GE GVK+VL ++ E M LSGC+S+ EIS Sbjct: 300 LGAAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEIS 350 >5ZBN-A nrPDB Length = 371 Score = 296 bits (757), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 162/348 (46%), Positives = 229/348 (65%), Gaps = 8/348 (2%) Query: 8 DFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRTTIQGQ 67 +++A A+K+L K +D+ A+D T +EN AF RI RPR L D+SK+D TT+ G Sbjct: 9 EYEAIAKKKLPKMVFDYYASGAEDQWTLAENRNAFSRILFRPRILIDVSKIDMSTTVLGF 68 Query: 68 EISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPEGFRWF 127 +IS PI I+PTA +A P+GE +TARAA A +SS+A+ S+E++ + P G R+F Sbjct: 69 KISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP-GIRFF 127 Query: 128 QLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRAL 187 QLY+ D + Q+V+RAE GFKA+ +T+DTP LG R D +N+ L + LK+ L Sbjct: 128 QLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTLKNFEGL 187 Query: 188 ---KEEKPTQSVPVSFPKA----SFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNV 240 K ++ + S S+ + W D+ LQ+IT LPI++KG+LT EDA LA++ Sbjct: 188 DLGKMDQASDSGLASYVAGQIDRTLSWKDVQWLQTITSLPILVKGVLTAEDARLAVQAGA 247 Query: 241 QGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIF 300 GI+VSNHG RQLD V ++I AL EVV A +G+I V++DGGVR GTDV KALALGA IF Sbjct: 248 AGIIVSNHGARQLDYVPSTIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGASGIF 307 Query: 301 LGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLI 348 +GRP+++ LA +GE G+K+VL +L E M LSGC+S+ EI+ + I Sbjct: 308 IGRPVVFSLAAEGEAGIKKVLQMLRDEFELTMALSGCRSLNEITRNHI 355 >1QCW-A nrPDB Length = 410 Score = 247 bits (631), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 138/362 (38%), Positives = 207/362 (57%), Gaps = 11/362 (3%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 ++ L DF+ A + L+K +W + A+D +T+ EN A+ RI +P+ L D+ KVD T Sbjct: 21 IINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILVDVRKVDIST 80 Query: 63 TIQGQEISAPICISPTAFHSIAWP-DGEKSTARAAQEA--NICYVISSYASYSLEDIVAA 119 + G + P +S TA + P +GEK AR + + +IS+ AS S E+I+ A Sbjct: 81 DMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLASCSPEEIIEA 140 Query: 120 AP--EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQL-NLE 176 AP + +W+QLY+ SD +V+ E LG KAL +T+D P LG + +D + + N + Sbjct: 141 APSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQKEKDMKLKFSNTK 200 Query: 177 ANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAM 236 A ++E + F S W D+ L+ T+LPI++KG+ ED A Sbjct: 201 AGFKAMKKTNVEESQGASRALSKFIDPSLTWKDIEELKKKTKLPIVIKGVQRTEDVIKAA 260 Query: 237 KHNVQGIVVSNHGGRQLDEVSASIDALREVVA-----AVKGKIEVYMDGGVRTGTDVLKA 291 + V G+V+SNHGGRQLD A I+ L E + +K K+EV++DGGVR GTDVLKA Sbjct: 261 EIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEVFVDGGVRRGTDVLKA 320 Query: 292 LALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFS 351 L LGA+ + LGRP L+ +C G +GV++ ++IL E+ M L G S+AE+ PDL+ S Sbjct: 321 LCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLGVTSIAELKPDLLDLS 380 Query: 352 RL 353 L Sbjct: 381 TL 382 >1SZG-A nrPDB Length = 511 Score = 245 bits (626), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 138/362 (38%), Positives = 206/362 (56%), Gaps = 11/362 (3%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 ++ L DF+ A + L+K +W + A+D +T+ EN A+ RI +P+ L D+ KVD T Sbjct: 122 IINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILVDVRKVDIST 181 Query: 63 TIQGQEISAPICISPTAFHSIAWP-DGEKSTARAAQEA--NICYVISSYASYSLEDIVAA 119 + G + P +S T + P +GEK AR + + +IS+ AS S E+I+ A Sbjct: 182 DMLGSHVDVPFYVSATGLCKLGNPLEGEKDVARGCGQGVTKVPQMISTAASCSPEEIIEA 241 Query: 120 AP--EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQL-NLE 176 AP + +W+QLY+ SD +V+ E LG KAL +T+D P LG R +D + + N + Sbjct: 242 APSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKDMKLKFSNTK 301 Query: 177 ANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAM 236 A ++E + F S W D+ L+ T+LPI++KG+ ED A Sbjct: 302 AGPKAMKKTNVEESQGASRALSKFIDPSLTWKDIEELKKKTKLPIVIKGVQRTEDVIKAA 361 Query: 237 KHNVQGIVVSNHGGRQLDEVSASIDALREVVA-----AVKGKIEVYMDGGVRTGTDVLKA 291 + V G+V+SNHGGRQLD A I+ L E + +K K+EV++DGGVR GTDVLKA Sbjct: 362 EIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEVFVDGGVRRGTDVLKA 421 Query: 292 LALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFS 351 L LGA+ + LGRP L+ +C G +GV++ ++IL E+ M L G S+AE+ PDL+ S Sbjct: 422 LCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLGVTSIAELKPDLLDLS 481 Query: 352 RL 353 L Sbjct: 482 TL 483 >2A85-A nrPDB Length = 380 Score = 222 bits (565), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 128/354 (36%), Positives = 202/354 (57%), Gaps = 11/354 (3%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 L + D++ AQK+L K +D++EG A+D N F++ R +P+ L D+S+ + Sbjct: 5 LFNVEDYRKLAQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVSRRSLQA 64 Query: 63 TIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPE 122 + G+ S P+ I PTA + WP G+ + ARAA +A I +V+S+ ++ S+ED+ A + Sbjct: 65 EVLGKRQSMPLLIGPTALNGALWPKGDLALARAATKAGIPFVLSTASNMSIEDL-ARQCD 123 Query: 123 GFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLK 182 G WFQLY+ + + MV +A G+ LV+T D V G R RD N+ + + LK Sbjct: 124 GDLWFQLYVIHR-EIAQGMVLKALHTGYTTLVLTTDVAVNGYRERDLHNRFKIPPFLTLK 182 Query: 183 DLRAL---KEEKPTQSVPVSFPK----ASFCWNDLSLLQSITRLPIILKGILTKEDAELA 235 + + K +K + + ASF W L L+ + +++KG+L+ EDA+ Sbjct: 183 NFEGIDLGKMDKANLEMQAALMSRQMDASFNWEALRWLRDLWPHKLLVKGLLSAEDADRC 242 Query: 236 MKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALG 295 + G+++SNHGGRQLD + ++ L + VA GK V +D G R G+D++KALALG Sbjct: 243 IAEGADGVILSNHGGRQLDCAISPMEVLAQSVAKT-GK-PVLIDSGFRRGSDIVKALALG 300 Query: 296 ARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQ 349 A + LGR L+GLA +GE GV EVL +L A++ R + GC + +SPD +Q Sbjct: 301 AEAVLLGRATLYGLAARGETGVDEVLTLLKADIDRTLAQIGCPDITSLSPDYLQ 354 >2CDH-0 nrPDB Length = 226 Score = 211 bits (537), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 120/275 (43%), Positives = 164/275 (59%), Gaps = 50/275 (18%) Query: 62 TTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAP 121 TTI G +IS PI I+PTA +A P+GE +TARAA A +SS+A+ S+E++ + P Sbjct: 2 TTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP 61 Query: 122 EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILL 181 G R+FQLY+ D + Q+V+RAE GFKA+ +T+ Sbjct: 62 -GIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTV------------------------ 96 Query: 182 KDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQ 241 W D++ LQ+IT LPI++KG++T EDA LA++H Sbjct: 97 -------------------------WKDVAWLQTITSLPILVKGVITAEDARLAVQHGAA 131 Query: 242 GIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFL 301 GI+VSNHG RQLD V A+I AL EVV A +G+I V++DGGVR GTDV KALALGA +F+ Sbjct: 132 GIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGAAGVFI 191 Query: 302 GRPILWGLACKGEDGVKEVLDILTAELHRCMTLSG 336 GRP+++ LA +GE GVK+VL ++ E M LSG Sbjct: 192 GRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSG 226 >6BFG-A nrPDB Length = 399 Score = 207 bits (528), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 127/373 (34%), Positives = 201/373 (53%), Gaps = 30/373 (8%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 L + D++ QK+L K +D++EG A+D N F++ R +P+ L D+S+ + Sbjct: 5 LFNVEDYRKLRQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVSRRSLQA 64 Query: 63 TIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPE 122 + G+ S P+ I PT + WP G+ + ARAA +A I +V+S+ ++ S+ED+ A + Sbjct: 65 EVLGKRQSMPLLIGPTGLNGALWPKGDLALARAATKAGIPFVLSTASNMSIEDL-ARQCD 123 Query: 123 GFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQ----LNLEAN 178 G WFQLY+ + + MV +A G+ LV+T D V G R RD N+ ++ A Sbjct: 124 GDLWFQLYVIHR-EIAQGMVLKALHTGYTTLVLTTDVAVNGYRERDLHNRFKIPMSYSAK 182 Query: 179 ILLK-------DLRALKEEKPTQSVPVSFPK---------------ASFCWNDLSLLQSI 216 ++L L ++ P + VS ASF W L L+ + Sbjct: 183 VVLDGCLHPRWSLDFVRHGMPQLANFVSSQTSSLEMQAALMSRQMDASFNWEALRWLRDL 242 Query: 217 TRLPIILKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEV 276 +++KG+L+ EDA+ + G+++SNHGGRQLD + ++ L + VA K V Sbjct: 243 WPHKLLVKGLLSAEDADRCIAEGADGVILSNHGGRQLDCAISPMEVLAQSVA--KTGKPV 300 Query: 277 YMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSG 336 +D G R G+D++KALALGA + LGR L+GLA +GE GV EVL +L A++ R + G Sbjct: 301 LIDSGFRRGSDIVKALALGAEAVLLGRATLYGLAARGETGVDEVLTLLKADIDRTLAQIG 360 Query: 337 CQSVAEISPDLIQ 349 C + +SPD +Q Sbjct: 361 CPDITSLSPDYLQ 373 >2J6X-A nrPDB Length = 374 Score = 206 bits (523), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 122/343 (35%), Positives = 177/343 (51%), Gaps = 3/343 (0%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 +V D + A K + +++I G + D T N A+K L PR +D+ DT T Sbjct: 19 VVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTST 78 Query: 63 TIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPE 122 I G +I AP ++P A H +A E TARA E IS+Y+ + E+I Sbjct: 79 EILGHKIKAPFIMAPIAAHGLAHTTKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNG 138 Query: 123 GFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQL--NLEANIL 180 G RWFQ+YM D N+ ++ A++ G A+++T D+ V GNR RD +N+ I+ Sbjct: 139 GPRWFQIYMAKDDQQNRDILDEAKSDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIV 198 Query: 181 LKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNV 240 + LR E ++ K D+ + + + LP+ +KGI EDA++A+K Sbjct: 199 QRYLRGTAEGMSLNNI-YGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGA 257 Query: 241 QGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIF 300 GI VSNHG RQL E S D L + V ++ + D GVR G V KALA GA + Sbjct: 258 SGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVA 317 Query: 301 LGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEI 343 LGRP+L+GLA G G VLD +L R M L+G Q+V ++ Sbjct: 318 LGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDL 360 >6DVI-A nrPDB Length = 394 Score = 193 bits (490), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 124/375 (33%), Positives = 190/375 (50%), Gaps = 31/375 (8%) Query: 4 VCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRTT 63 + AD++AHAQ+ L ++ G + D T N+ AFK L PR L ++ D Sbjct: 25 MSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVE 84 Query: 64 IQGQEISAPICISPTAFHSIAWPDG--EKSTARAAQEANICYVISSYASYSLEDIVAAAP 121 + G+ +AP+ +P ++ DG + ++A+A+ + Y+ S+ A SLEDI A Sbjct: 85 LWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAG 144 Query: 122 EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILL 181 + +FQLY D D + ++RAE G+ LVIT+DT + G R RD L + L Sbjct: 145 DTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRD----LTISNFPFL 200 Query: 182 KDL------------RALKEEKPTQS--------VPVSFPKASF----CWNDLSLLQSIT 217 + L + K ++ + F F W D+ ++SIT Sbjct: 201 RGLCLTNYVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSIT 260 Query: 218 RLPIILKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVY 277 ++P+ILKGI +DA A+ V GI SNHGGRQ + ++D L EVV A G V Sbjct: 261 KMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKA-SGDTPVL 319 Query: 278 MDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGC 337 D G+RTG DV+KALA+GA + +GRP WG A G G++ V L AE M + G Sbjct: 320 FDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGY 379 Query: 338 QSVAEISPDLIQFSR 352 +++ E++ D ++ +R Sbjct: 380 RNLKELTIDALRPTR 394 >3SR7-A nrPDB Length = 365 Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 78/329 (23%), Positives = 137/329 (41%), Gaps = 60/329 (18%) Query: 49 PRYLRDMSKVDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSY 108 P Y D++++D T GQ+ P I+ S G++ + AQ A+ C ++ Sbjct: 67 PDY--DLAEIDLSTHFAGQDFDFPFYINAMTGGS---QKGKEVNEKLAQVADTCGLLFVT 121 Query: 109 ASYSLEDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRD 168 SYS +K+ D + Q V+++ A I +D P + Sbjct: 122 GSYSTA----------------LKNPDDTSYQ-VKKSRPHLLLATNIGLDKPYQAGLQAV 164 Query: 169 KRNQ-LNLEANI-LLKDLRALKEEKPTQSVPVSFPKASFCWN-DLSLLQSITRLPIILKG 225 + Q L L+ +I L+++L + E+ +S W LS +LP ILK Sbjct: 165 RDLQPLFLQVHINLMQELLMPEGEREFRS-----------WKKHLSDYAKKLQLPFILKE 213 Query: 226 ILTKEDA---ELAMKHNVQGIVVSNHGGRQLDEVS-------ASIDALREVVAAV----- 270 + D + A+ V+ + +S GG + + ++ + A V Sbjct: 214 VGFGMDVKTIQTAIDLGVKTVDISGRGGTSFAYIENRRGGNRSYLNQWGQTTAQVLLNAQ 273 Query: 271 --KGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTA-- 326 K+E+ GG+R D++KAL LGA+ + L R + L + V EV+ I+ Sbjct: 274 PLMDKVEILASGGIRHPLDIIKALVLGAKAVGLSRTM---LELVEQHSVHEVIAIVNGWK 330 Query: 327 -ELHRCMTLSGCQSVAEI-SPDLIQFSRL 353 +L M CQ++AE+ + D + + RL Sbjct: 331 EDLRLIMCALNCQTIAELRNVDYLLYGRL 359 >1P0K-A nrPDB Length = 349 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 38/65 (58%) Query: 279 DGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQ 338 GG++ DV KA+ALGA C + L L GE+G+ E + ++ EL MT+ G + Sbjct: 257 SGGLQDALDVAKAIALGASCTGMAGHFLKALTDSGEEGLLEEIQLILEELKLIMTVLGAR 316 Query: 339 SVAEI 343 ++A++ Sbjct: 317 TIADL 321 >4N02-A nrPDB Length = 357 Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 69/323 (21%), Positives = 133/323 (41%), Gaps = 52/323 (16%) Query: 52 LRDMSKVDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASY 111 L ++ ++D T G++ P I+ S + + A+ A+ I +V SY++ Sbjct: 56 LYNLDEIDLSTEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSA- 114 Query: 112 SLEDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPV-LGNRRRDKR 170 L +D F+ + LG I +D PV LG + ++ Sbjct: 115 ----------------ALKNPTDDSFSVKSSHPNLLLGTN---IGLDKPVELGLQTVEEM 155 Query: 171 NQLNLEANI-LLKDLRALKEEKPTQSVPVSFPKASFCW-NDLSLLQSITRLPIILKGILT 228 N + L+ ++ ++++L + E+ +S W + L+ +PI+LK + Sbjct: 156 NPVLLQVHVNVMQELLMPEGERKFRS-----------WQSHLADYSKQIPVPIVLKEVGF 204 Query: 229 KEDA---ELAMKHNVQGIVVSNHGGRQLDEV----SASIDALREVVAAV----------K 271 DA E A + V+ + +S GG + S D L + + K Sbjct: 205 GMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRRSGQRDYLNQWGQSTMQALLNAQEWK 264 Query: 272 GKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRC 331 K+E+ + GGVR D++K L GA+ + L R +L + + V ++ A+L Sbjct: 265 DKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRTVLELVETYTVEEVIGIVQGWKADLRLI 324 Query: 332 MTLSGCQSVAEISP-DLIQFSRL 353 M C ++A++ D + + +L Sbjct: 325 MCSLNCATIADLQKVDYLLYGKL 347 >2ZRW-A nrPDB Length = 368 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Query: 280 GGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQS 339 GG+R+G D KA+ALGA + P+L A +G++ +++ + EL M L+G + Sbjct: 274 GGIRSGLDAAKAIALGADIAGMALPVLKS-AIEGKESLEQFFRKIIFELKAAMMLTGSKD 332 Query: 340 V 340 V Sbjct: 333 V 333 >1UUO-A nrPDB Length = 372 Score = 35.0 bits (79), Expect = 0.043, Method: Compositional matrix adjust. Identities = 41/152 (26%), Positives = 65/152 (42%), Gaps = 40/152 (26%) Query: 217 TRLPIILKGI---LTKEDAE----LAMKHNVQGIVVSNH-------------------GG 250 TR P +L I LT +D E +A + + G++V+N G Sbjct: 223 TRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSG 282 Query: 251 RQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGAR-------CIFLGR 303 + L ++S +RE+ A +G+I + GGV +G D L+ + GA IFLG Sbjct: 283 KPLRDLSTQ--TIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGP 340 Query: 304 PILWGL-----ACKGEDGVKEVLDILTAELHR 330 P++ + A E G V D + A+ R Sbjct: 341 PVVVRVKRELEALLKERGFTTVTDAIGADHRR 372 >5AHL-A nrPDB Length = 400 Score = 34.3 bits (77), Expect = 0.075, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Query: 260 IDALREVVAAVKGK-IEVYMDGGVRTGTDVLKALALGARCIFLG 302 I A+ V AA++G + + DGG+R D+ KA+ GA C+ +G Sbjct: 228 ISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMG 271 >4DQW-A nrPDB Length = 509 Score = 34.3 bits (77), Expect = 0.077, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Query: 260 IDALREVVAAVKGK-IEVYMDGGVRTGTDVLKALALGARCIFLG 302 I A+ V AA++G + + DGG+R D+ KA+ GA C+ +G Sbjct: 337 ISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMG 380 >4FEZ-A nrPDB Length = 388 Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 274 IEVYMDGGVRTGTDVLKALALGARCIFLG 302 I V DGG+R D+ KA+A GA C+ +G Sbjct: 234 IPVIADGGIRFSGDISKAIAAGASCVMVG 262 >4FXS-A nrPDB Length = 496 Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 274 IEVYMDGGVRTGTDVLKALALGARCIFLG 302 I V DGG+R D+ KA+A GA C+ +G Sbjct: 335 IPVIADGGIRFSGDISKAIAAGASCVMVG 363 >3TSB-A nrPDB Length = 511 Score = 32.3 bits (72), Expect = 0.28, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 21/34 (61%) Query: 269 AVKGKIEVYMDGGVRTGTDVLKALALGARCIFLG 302 A K I V DGG++ D++KALA GA + LG Sbjct: 355 ARKHGIPVIADGGIKYSGDMVKALAAGAHVVMLG 388 >1VRD-A nrPDB Length = 494 Score = 32.3 bits (72), Expect = 0.28, Method: Compositional matrix adjust. Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 19/97 (19%) Query: 219 LPIILKGILTKEDAELAMKHNVQGI-------------VVSNHGGRQLDEVSASIDALRE 265 LP++ + T E E +K + VV+ G QL V + R Sbjct: 279 LPVVAGNVATPEGTEALIKAGADAVKVGVGPGSICTTRVVAGVGVPQLTAVMECSEVAR- 337 Query: 266 VVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLG 302 K + + DGG+R D++KALA GA + +G Sbjct: 338 -----KYDVPIIADGGIRYSGDIVKALAAGAESVMVG 369 >3FFS-A nrPDB Length = 400 Score = 32.3 bits (72), Expect = 0.32, Method: Compositional matrix adjust. Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 269 AVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAEL 328 A K I + DGG+R D+ KALA+GA + +G IL G + G KE++ + Sbjct: 242 ASKFGIPIIADGGIRYSGDIGKALAVGASSVMIG-SILAG--TEESPGEKELIGDTVYKY 298 Query: 329 HRCMTLSGC 337 +R M G Sbjct: 299 YRGMGSVGA 307 >1JUE-A nrPDB Length = 311 Score = 32.3 bits (72), Expect = 0.34, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 8/85 (9%) Query: 263 LREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLD 322 +R +K +I++ GG+ TG D + L GA + +G L +G + D Sbjct: 232 VRAFYTRLKPEIQIIGTGGIETGQDAFEHLLCGATMLQIGT----ALHKEG----PAIFD 283 Query: 323 ILTAELHRCMTLSGCQSVAEISPDL 347 + EL M G QS+A+ L Sbjct: 284 RIIKELEEIMNQKGYQSIADFHGKL 308 >4MJM-A nrPDB Length = 385 Score = 32.3 bits (72), Expect = 0.36, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 21/34 (61%) Query: 269 AVKGKIEVYMDGGVRTGTDVLKALALGARCIFLG 302 A K I V DGG++ D++KALA GA + LG Sbjct: 229 ARKHGIPVIADGGIKYSGDMVKALAAGAHVVMLG 262 >1JCN-A nrPDB Length = 514 Score = 32.0 bits (71), Expect = 0.37, Method: Compositional matrix adjust. Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 4/49 (8%) Query: 274 IEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE----DGVK 318 + + DGG++T V+KALALGA + +G + GE DGV+ Sbjct: 359 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVR 407 >3U2O-A nrPDB Length = 395 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 8/93 (8%) Query: 239 NVQGIVVSNHGG---RQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALG 295 +QG + S GG + L ++S +RE+ A +G++ + GGV +G D L+ + G Sbjct: 291 GLQGALRSETGGLSGKPLRDLSTQ--TIREMYALTQGRVPIIGVGGVSSGQDALEKIRAG 348 Query: 296 ARCIFLGRPI-LWGLACKGEDGVKEVLDILTAE 327 A + L + WG G+ VK L+ L E Sbjct: 349 ASLVQLYTALTFWGPPVVGK--VKRELEALLKE 379 >3R2G-A nrPDB Length = 361 Score = 31.6 bits (70), Expect = 0.54, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 276 VYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 + DGG++T D++KALA GA + +G + GE Sbjct: 202 IVADGGIKTSGDIVKALAFGADFVMIGGMLAGSAPTPGE 240 >4QJ1-A nrPDB Length = 361 Score = 31.6 bits (70), Expect = 0.61, Method: Compositional matrix adjust. Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 269 AVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAEL 328 A K I + DGG+R D+ KALA+GA + +G IL G + G KE++ + Sbjct: 203 ASKFGIPIIADGGIRYSGDIGKALAVGASSVMIG-SILAG--TEESPGEKELIGDTVYKY 259 Query: 329 HRCMTLSGC 337 +R M G Sbjct: 260 YRGMGSVGA 268 >2CU0-A nrPDB Length = 486 Score = 31.2 bits (69), Expect = 0.70, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 18/27 (66%) Query: 276 VYMDGGVRTGTDVLKALALGARCIFLG 302 V DGG+R D++KA+A GA + LG Sbjct: 331 VIADGGIRYSGDIVKAIAAGADAVMLG 357 >5UQG-A nrPDB Length = 406 Score = 30.8 bits (68), Expect = 0.85, Method: Compositional matrix adjust. Identities = 18/44 (40%), Positives = 26/44 (59%), Gaps = 1/44 (2%) Query: 260 IDALREVVA-AVKGKIEVYMDGGVRTGTDVLKALALGARCIFLG 302 I A+ E V A K + V DGG++ D+ KALA+GA + +G Sbjct: 235 ISAIDECVEEANKFGVPVIADGGIKYSGDIAKALAVGASSVMIG 278 >1EEP-A nrPDB Length = 404 Score = 30.8 bits (68), Expect = 0.99, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 276 VYMDGGVRTGTDVLKALALGARCIFLGR 303 + DGG+R DV+KA+A GA + +G Sbjct: 259 IIADGGIRFSGDVVKAIAAGADSVMIGN 286 >5UPU-A nrPDB Length = 407 Score = 30.8 bits (68), Expect = 1.00, Method: Compositional matrix adjust. Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Query: 260 IDALREVVAAVK-GKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLA 310 I A+ E VAA + + V DGG++ D+ KALA GA LG +L G A Sbjct: 232 ITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAGASTAMLGS-LLAGTA 282 >1ZFJ-A nrPDB Length = 491 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 3/53 (5%) Query: 250 GRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLG 302 G + +V+A DA VA GK + DGG++ D++KALA G + LG Sbjct: 316 GVGVPQVTAIYDA--AAVAREYGKT-IIADGGIKYSGDIVKALAAGGNAVMLG 365 >1KAE-A nrPDB Length = 434 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Query: 136 DFNKQM-VQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANIL 180 DF K+M VQ GF AL TI+T R +N + L N L Sbjct: 385 DFQKRMTVQELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNAL 430 >5LSM-A nrPDB Length = 359 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 7/97 (7%) Query: 241 QGIVVSNHGGR----QLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGA 296 QG+ H G L E + L +++AAV+ I V GG+ T V A+ +GA Sbjct: 175 QGLEAGGHRGHFLSEDLTEQLGTFSLLPQIIAAVE--IPVIAAGGIVDATTVRAAMTMGA 232 Query: 297 RCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMT 333 + +G L C +E L A+ H +T Sbjct: 233 SAVQVGTAYLLCPECNTSAIHREALQSDAAQ-HTALT 268 >2JS7-A nrPDB Length = 160 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 26/51 (50%) Query: 112 SLEDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVL 162 +L+D + PE F F Y SD F ++M+++ E ++ + D VL Sbjct: 5 TLDDPLGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVL 55 >1YPF-A nrPDB Length = 336 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 11/24 (45%), Positives = 16/24 (66%) Query: 279 DGGVRTGTDVLKALALGARCIFLG 302 DGG+RT DV K++ GA + +G Sbjct: 216 DGGIRTNGDVAKSIRFGATMVMIG 239 >6I0M-A nrPDB Length = 517 Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Query: 274 IEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE----DGVK 318 + V DGG++ + KALALGA + +G + GE DG++ Sbjct: 362 VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIR 410 >4JDY-A nrPDB Length = 264 Score = 28.5 bits (62), Expect = 4.2, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 26/52 (50%) Query: 255 EVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPIL 306 E+ A + + EV A K + ++ GG+ T D + LGA +F+G I Sbjct: 183 ELQAPYELVAEVARAGKLPVTLFTAGGIATPADAAMMMQLGAEGVFVGSGIF 234 >4Q4K-A nrPDB Length = 357 Score = 28.5 bits (62), Expect = 4.9, Method: Compositional matrix adjust. Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 12/126 (9%) Query: 184 LRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNV--- 240 L L EE+P VSF + + + LQ++ +L T E+A L Sbjct: 119 LPMLLEERPAA---VSFHFGAPPRDQVRALQAVGIR--VLVCATTPEEAALVEAAGADAV 173 Query: 241 --QGIVVSNHGGR-QLDEVSASIDALREV-VAAVKGKIEVYMDGGVRTGTDVLKALALGA 296 QGI H G + + A+I L V + A +G + V GG+ G + AL LGA Sbjct: 174 VAQGIEAGGHRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRGIRAALELGA 233 Query: 297 RCIFLG 302 + +G Sbjct: 234 SAVQMG 239 >5CSS-A nrPDB Length = 226 Score = 28.1 bits (61), Expect = 5.6, Method: Compositional matrix adjust. Identities = 14/51 (27%), Positives = 29/51 (56%), Gaps = 1/51 (1%) Query: 257 SASIDALREVVAAVKGK-IEVYMDGGVRTGTDVLKALALGARCIFLGRPIL 306 +A + + ++V +G V + G++TG DV +++ LGAR I + ++ Sbjct: 152 TAKPEIIEDIVKIYEGTGTSVLVGAGIKTGEDVRRSIGLGARGILVASGVV 202 >1HG3-A nrPDB Length = 225 Score = 28.1 bits (61), Expect = 6.3, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 5/61 (8%) Query: 265 EVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDIL 324 E+V V +++V G+ TG DV KA+ LG + L + K +D K + D++ Sbjct: 168 ELVKKVNPEVKVLCGAGISTGEDVKKAIELGTVGVLLASGV-----TKAKDPEKAIWDLV 222 Query: 325 T 325 + Sbjct: 223 S 223 >2ISS-A nrPDB Length = 313 Score = 28.1 bits (61), Expect = 6.6, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 26/52 (50%) Query: 255 EVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPIL 306 E+ A ++ LREV + + + GGV T D + LGA +F+G I Sbjct: 209 EIGAPVELLREVKRLGRLPVVNFAAGGVATPADAALMMMLGADGVFVGSGIF 260 >6I4B-A nrPDB Length = 405 Score = 27.7 bits (60), Expect = 7.2, Method: Compositional matrix adjust. Identities = 25/136 (18%), Positives = 51/136 (37%), Gaps = 46/136 (33%) Query: 229 KEDAELAMKHNVQGIVVSNH-----------------GGRQLDEVSASIDALREVVAAVK 271 KE A++ ++ N+ G+++SN G +L ++S + E+ Sbjct: 276 KEIADVLLETNIDGMIISNTTTQINDIKSFENKKGGVSGAKLKDISTKF--ICEMYNYTN 333 Query: 272 GKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRC 331 +I + GG+ +G D L+ + GA +L+ C Sbjct: 334 KQIPIIASGGIFSGLDALEKIEAGAS---------------------------VCQLYSC 366 Query: 332 MTLSGCQSVAEISPDL 347 + +G +S +I +L Sbjct: 367 LVFNGMKSAVQIKREL 382 >2ZCW-A nrPDB Length = 202 Score = 27.7 bits (60), Expect = 8.2, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 9/67 (13%) Query: 230 EDAELAMKHNVQGIVV--SNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTD 287 E +E + H +G VV + H DE++A++ ++RE V V G E+ +G +R+G Sbjct: 129 ELSETPLAHEEEGKVVLKATH-----DELAAAVGSVRETVTKVIG--ELAREGYIRSGYG 181 Query: 288 VLKALAL 294 ++ L L Sbjct: 182 KIQLLDL 188 >1EUF-A nrPDB Length = 227 Score = 27.3 bits (59), Expect = 9.5, Method: Compositional matrix adjust. Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 4/98 (4%) Query: 173 LNLEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDA 232 L N+ L ++ E+ Q +PV P +ND +L I L + K +T + + Sbjct: 46 LGSSINVTLGAHNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVS 105 Query: 233 ELAMKHNV----QGIVVSNHGGRQLDEVSASIDALREV 266 + + ++ G++ S G +L S D L+EV Sbjct: 106 PINLPRSLAEVKPGMMCSVAGWGRLGVNMPSTDKLQEV 143 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3SGZ-A nrPDB 503 e-143 2RDU-A nrPDB 462 e-130 1AL8-A nrPDB 459 e-129 5ZBN-A nrPDB 453 e-128 2A85-A nrPDB 428 e-120 1SZG-A nrPDB 418 e-117 1QCW-A nrPDB 418 e-117 6BFG-A nrPDB 412 e-115 2J6X-A nrPDB 404 e-113 6DVI-A nrPDB 398 e-111 2CDH-0 nrPDB 288 3e-78 4N02-A nrPDB 267 5e-72 3SR7-A nrPDB 251 3e-67 1P0K-A nrPDB 145 3e-35 2ZRW-A nrPDB 108 3e-24 Sequences not found previously or not previously below threshold: 3DH7-A nrPDB 67 2e-11 3FFS-A nrPDB 54 1e-07 4QJ1-A nrPDB 52 5e-07 1VRD-A nrPDB 51 1e-06 4MJM-A nrPDB 49 2e-06 3TSB-A nrPDB 48 8e-06 1JCN-A nrPDB 47 9e-06 2GJN-A nrPDB 47 1e-05 4FXS-A nrPDB 47 1e-05 6I0M-A nrPDB 47 2e-05 4FEZ-A nrPDB 47 2e-05 5LSM-A nrPDB 46 3e-05 4Z87-A nrPDB 45 4e-05 4XTI-A nrPDB 45 4e-05 1ZFJ-A nrPDB 45 4e-05 4DQW-A nrPDB 44 7e-05 5AHL-A nrPDB 44 9e-05 2GGG-A nrPDB 44 9e-05 4AF0-B nrPDB 44 1e-04 5UQG-A nrPDB 42 3e-04 1YPF-A nrPDB 42 4e-04 5UPU-A nrPDB 41 0.001 2CU0-A nrPDB 40 0.001 4Q4K-A nrPDB 40 0.002 1TYG-A nrPDB 39 0.003 3R2G-A nrPDB 39 0.003 3OIX-A nrPDB 39 0.003 1UUO-A nrPDB 39 0.003 5Z9Y-A nrPDB 38 0.006 1EEP-A nrPDB 38 0.007 2H6R-A nrPDB 37 0.010 2C6Q-A nrPDB 37 0.011 1JUE-A nrPDB 37 0.013 6I4B-A nrPDB 37 0.017 1TV5-A nrPDB 37 0.017 6HYE-A nrPDB 36 0.021 4JDY-A nrPDB 36 0.022 2BWG-A nrPDB 36 0.023 3T55-A nrPDB 35 0.042 1MZH-A nrPDB 35 0.047 1HG3-A nrPDB 35 0.048 3U2O-A nrPDB 35 0.051 2ISS-A nrPDB 35 0.059 4WY0-A nrPDB 35 0.063 4UTT-A nrPDB 34 0.082 1B0U-A nrPDB 34 0.087 5ZKN-A nrPDB 34 0.12 2XZ9-A nrPDB 34 0.13 2NV2-A nrPDB 34 0.13 4XZ9-A nrPDB 34 0.13 1TJR-A nrPDB 33 0.16 5CSS-A nrPDB 33 0.17 2Z6J-A nrPDB 33 0.17 1MJH-A nrPDB 33 0.18 4N6F-A nrPDB 33 0.18 1WV2-A nrPDB 33 0.19 3W7D-A nrPDB 32 0.28 6B8S-A nrPDB 32 0.33 1AK5-A nrPDB 32 0.37 2YZR-A nrPDB 32 0.42 5K8C-A nrPDB 32 0.56 3O07-A nrPDB 32 0.56 3L5A-A nrPDB 31 0.61 1OK6-A nrPDB 31 0.66 1VHN-A nrPDB 31 0.68 1H5Y-A nrPDB 31 0.81 2YZ2-A nrPDB 31 0.94 4FIQ-A nrPDB 31 0.95 1WX0-A nrPDB 30 1.2 4ADT-A nrPDB 30 1.2 2Y88-A nrPDB 30 1.2 4EVZ-A nrPDB 30 1.3 5LNT-A nrPDB 30 1.4 1N7K-A nrPDB 30 1.5 2ZBT-A nrPDB 30 1.8 3GNN-A nrPDB 30 2.1 4AXK-A nrPDB 30 2.2 1KA9-F nrPDB 29 2.2 5LNS-A nrPDB 29 2.3 1UB3-A nrPDB 29 2.5 1O4U-A nrPDB 29 2.5 4Z7R-A nrPDB 29 3.0 5UE9-A nrPDB 29 3.1 2X0S-A nrPDB 29 3.1 4MM1-A nrPDB 29 3.5 1W0M-A nrPDB 29 3.6 3BW4-A nrPDB 29 3.6 6OD1-A nrPDB 29 3.9 4RY2-A nrPDB 29 3.9 3EOD-A nrPDB 29 4.1 3IJQ-A nrPDB 29 4.3 4WQ4-C nrPDB 29 4.5 5G1T-A nrPDB 29 4.7 4IQL-A nrPDB 28 5.4 3N2C-A nrPDB 28 5.5 2NU8-B nrPDB 28 6.5 2ONK-A nrPDB 28 7.1 3NG3-A nrPDB 28 8.3 >3SGZ-A nrPDB Length = 352 Score = 503 bits (1295), Expect = e-143, Method: Composition-based stats. Identities = 348/352 (98%), Positives = 348/352 (98%) Query: 2 PLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTR 61 PLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTR Sbjct: 1 PLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTR 60 Query: 62 TTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAP 121 TTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAP Sbjct: 61 TTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAP 120 Query: 122 EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILL 181 EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANIL Sbjct: 121 EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILK 180 Query: 182 KDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQ 241 LRALKEEKPTQSVPV FPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQ Sbjct: 181 AALRALKEEKPTQSVPVLFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQ 240 Query: 242 GIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFL 301 GIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFL Sbjct: 241 GIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFL 300 Query: 302 GRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL 353 GRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL Sbjct: 301 GRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL 352 >2RDU-A nrPDB Length = 387 Score = 462 bits (1188), Expect = e-130, Method: Composition-based stats. Identities = 160/361 (44%), Positives = 233/361 (64%), Gaps = 10/361 (2%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 L+C+ D++ HA+ L K+ +D+ A+D T ++NIAAF R +L PR LR++++ D T Sbjct: 22 LICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLST 81 Query: 63 TIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPE 122 ++ GQ +S PIC+ TA +A DGE +T RA Q ++SS+A+ S+E++ A PE Sbjct: 82 SVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPE 141 Query: 123 GFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLK 182 RW QLY+ D + K++V++AE +G+KA+ +T+DTP LGNR D RN+ L + +K Sbjct: 142 ALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMK 201 Query: 183 DL----------RALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDA 232 + ++ + S W D+ L+ +T LPI+ KGIL +DA Sbjct: 202 NFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDA 261 Query: 233 ELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKAL 292 A+KH + GI+VSNHG RQLD V A+ID L E+V AV+GK+EV++DGGVR GTDVLKAL Sbjct: 262 REAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKAL 321 Query: 293 ALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSR 352 ALGA+ +F+GRPI+WGLA +GE GV++VL+IL E M LSGCQ+V I L++ + Sbjct: 322 ALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNP 381 Query: 353 L 353 L Sbjct: 382 L 382 >1AL8-A nrPDB Length = 359 Score = 459 bits (1180), Expect = e-129, Method: Composition-based stats. Identities = 160/355 (45%), Positives = 227/355 (63%), Gaps = 8/355 (2%) Query: 1 MPLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDT 60 M + + +++A A+++L K +D+ A+D T +EN AF RI RPR L D++ +D Sbjct: 1 MEITNVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDM 60 Query: 61 RTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAA 120 TTI G +IS PI I+PTA +A P+GE +TARAA A +SS+A+ S+E++ + Sbjct: 61 TTTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTG 120 Query: 121 PEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANIL 180 P G R+FQLY+ D + Q+V+RAE GFKA+ +T+DTP LG R D +N+ L + Sbjct: 121 P-GIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLT 179 Query: 181 LKDLRAL-------KEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAE 233 LK+ + + S S W D++ LQ+IT LPI++KG++T EDA Sbjct: 180 LKNFEGIDLGKMDKANDSGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDAR 239 Query: 234 LAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALA 293 LA++H GI+VSNHG RQLD V A+I AL EVV A +G+I V++DGGVR GTDV KALA Sbjct: 240 LAVQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALA 299 Query: 294 LGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLI 348 LGA +F+GRP+++ LA +GE GVK+VL ++ E M LSGC+S+ EIS I Sbjct: 300 LGAAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHI 354 >5ZBN-A nrPDB Length = 371 Score = 453 bits (1164), Expect = e-128, Method: Composition-based stats. Identities = 160/354 (45%), Positives = 226/354 (63%), Gaps = 8/354 (2%) Query: 2 PLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTR 61 + + +++A A+K+L K +D+ A+D T +EN AF RI RPR L D+SK+D Sbjct: 3 EVTNVMEYEAIAKKKLPKMVFDYYASGAEDQWTLAENRNAFSRILFRPRILIDVSKIDMS 62 Query: 62 TTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAP 121 TT+ G +IS PI I+PTA +A P+GE +TARAA A +SS+A+ S+E++ + P Sbjct: 63 TTVLGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP 122 Query: 122 EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILL 181 G R+FQLY+ D + Q+V+RAE GFKA+ +T+DTP LG R D +N+ L + L Sbjct: 123 -GIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTL 181 Query: 182 KDLRAL-------KEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAEL 234 K+ L + S + W D+ LQ+IT LPI++KG+LT EDA L Sbjct: 182 KNFEGLDLGKMDQASDSGLASYVAGQIDRTLSWKDVQWLQTITSLPILVKGVLTAEDARL 241 Query: 235 AMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALAL 294 A++ GI+VSNHG RQLD V ++I AL EVV A +G+I V++DGGVR GTDV KALAL Sbjct: 242 AVQAGAAGIIVSNHGARQLDYVPSTIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALAL 301 Query: 295 GARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLI 348 GA IF+GRP+++ LA +GE G+K+VL +L E M LSGC+S+ EI+ + I Sbjct: 302 GASGIFIGRPVVFSLAAEGEAGIKKVLQMLRDEFELTMALSGCRSLNEITRNHI 355 >2A85-A nrPDB Length = 380 Score = 428 bits (1099), Expect = e-120, Method: Composition-based stats. Identities = 127/354 (35%), Positives = 201/354 (56%), Gaps = 11/354 (3%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 L + D++ AQK+L K +D++EG A+D N F++ R +P+ L D+S+ + Sbjct: 5 LFNVEDYRKLAQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVSRRSLQA 64 Query: 63 TIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPE 122 + G+ S P+ I PTA + WP G+ + ARAA +A I +V+S+ ++ S+ED+ A + Sbjct: 65 EVLGKRQSMPLLIGPTALNGALWPKGDLALARAATKAGIPFVLSTASNMSIEDL-ARQCD 123 Query: 123 GFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLK 182 G WFQLY+ + + MV +A G+ LV+T D V G R RD N+ + + LK Sbjct: 124 GDLWFQLYVIH-REIAQGMVLKALHTGYTTLVLTTDVAVNGYRERDLHNRFKIPPFLTLK 182 Query: 183 DLRAL---KEEKPTQSVPVSF----PKASFCWNDLSLLQSITRLPIILKGILTKEDAELA 235 + + K +K + + ASF W L L+ + +++KG+L+ EDA+ Sbjct: 183 NFEGIDLGKMDKANLEMQAALMSRQMDASFNWEALRWLRDLWPHKLLVKGLLSAEDADRC 242 Query: 236 MKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALG 295 + G+++SNHGGRQLD + ++ L + VA K V +D G R G+D++KALALG Sbjct: 243 IAEGADGVILSNHGGRQLDCAISPMEVLAQSVA--KTGKPVLIDSGFRRGSDIVKALALG 300 Query: 296 ARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQ 349 A + LGR L+GLA +GE GV EVL +L A++ R + GC + +SPD +Q Sbjct: 301 AEAVLLGRATLYGLAARGETGVDEVLTLLKADIDRTLAQIGCPDITSLSPDYLQ 354 >1SZG-A nrPDB Length = 511 Score = 418 bits (1075), Expect = e-117, Method: Composition-based stats. Identities = 138/362 (38%), Positives = 206/362 (56%), Gaps = 11/362 (3%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 ++ L DF+ A + L+K +W + A+D +T+ EN A+ RI +P+ L D+ KVD T Sbjct: 122 IINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILVDVRKVDIST 181 Query: 63 TIQGQEISAPICISPTAFHSIAWP-DGEKSTARAAQEA--NICYVISSYASYSLEDIVAA 119 + G + P +S T + P +GEK AR + + +IS+ AS S E+I+ A Sbjct: 182 DMLGSHVDVPFYVSATGLCKLGNPLEGEKDVARGCGQGVTKVPQMISTAASCSPEEIIEA 241 Query: 120 AP--EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQL-NLE 176 AP + +W+QLY+ SD +V+ E LG KAL +T+D P LG R +D + + N + Sbjct: 242 APSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKDMKLKFSNTK 301 Query: 177 ANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAM 236 A ++E + F S W D+ L+ T+LPI++KG+ ED A Sbjct: 302 AGPKAMKKTNVEESQGASRALSKFIDPSLTWKDIEELKKKTKLPIVIKGVQRTEDVIKAA 361 Query: 237 KHNVQGIVVSNHGGRQLDEVSASIDALREVVA-----AVKGKIEVYMDGGVRTGTDVLKA 291 + V G+V+SNHGGRQLD A I+ L E + +K K+EV++DGGVR GTDVLKA Sbjct: 362 EIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEVFVDGGVRRGTDVLKA 421 Query: 292 LALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFS 351 L LGA+ + LGRP L+ +C G +GV++ ++IL E+ M L G S+AE+ PDL+ S Sbjct: 422 LCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLGVTSIAELKPDLLDLS 481 Query: 352 RL 353 L Sbjct: 482 TL 483 >1QCW-A nrPDB Length = 410 Score = 418 bits (1073), Expect = e-117, Method: Composition-based stats. Identities = 138/362 (38%), Positives = 207/362 (57%), Gaps = 11/362 (3%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 ++ L DF+ A + L+K +W + A+D +T+ EN A+ RI +P+ L D+ KVD T Sbjct: 21 IINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILVDVRKVDIST 80 Query: 63 TIQGQEISAPICISPTAFHSIAWP-DGEKSTARAAQEA--NICYVISSYASYSLEDIVAA 119 + G + P +S TA + P +GEK AR + + +IS+ AS S E+I+ A Sbjct: 81 DMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLASCSPEEIIEA 140 Query: 120 AP--EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQL-NLE 176 AP + +W+QLY+ SD +V+ E LG KAL +T+D P LG + +D + + N + Sbjct: 141 APSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQKEKDMKLKFSNTK 200 Query: 177 ANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAM 236 A ++E + F S W D+ L+ T+LPI++KG+ ED A Sbjct: 201 AGFKAMKKTNVEESQGASRALSKFIDPSLTWKDIEELKKKTKLPIVIKGVQRTEDVIKAA 260 Query: 237 KHNVQGIVVSNHGGRQLDEVSASIDALREVVA-----AVKGKIEVYMDGGVRTGTDVLKA 291 + V G+V+SNHGGRQLD A I+ L E + +K K+EV++DGGVR GTDVLKA Sbjct: 261 EIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEVFVDGGVRRGTDVLKA 320 Query: 292 LALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFS 351 L LGA+ + LGRP L+ +C G +GV++ ++IL E+ M L G S+AE+ PDL+ S Sbjct: 321 LCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLGVTSIAELKPDLLDLS 380 Query: 352 RL 353 L Sbjct: 381 TL 382 >6BFG-A nrPDB Length = 399 Score = 412 bits (1059), Expect = e-115, Method: Composition-based stats. Identities = 126/373 (33%), Positives = 198/373 (53%), Gaps = 30/373 (8%) Query: 3 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 62 L + D++ QK+L K +D++EG A+D N F++ R +P+ L D+S+ + Sbjct: 5 LFNVEDYRKLRQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVSRRSLQA 64 Query: 63 TIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPE 122 + G+ S P+ I PT + WP G+ + ARAA +A I +V+S+ ++ S+ED+ A + Sbjct: 65 EVLGKRQSMPLLIGPTGLNGALWPKGDLALARAATKAGIPFVLSTASNMSIEDL-ARQCD 123 Query: 123 GFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLK 182 G WFQLY+ + + MV +A G+ LV+T D V G R RD N+ + + K Sbjct: 124 GDLWFQLYVIH-REIAQGMVLKALHTGYTTLVLTTDVAVNGYRERDLHNRFKIPMSYSAK 182 Query: 183 -----------DLRALKEEKPTQSVPVSF---------------PKASFCWNDLSLLQSI 216 L ++ P + VS ASF W L L+ + Sbjct: 183 VVLDGCLHPRWSLDFVRHGMPQLANFVSSQTSSLEMQAALMSRQMDASFNWEALRWLRDL 242 Query: 217 TRLPIILKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEV 276 +++KG+L+ EDA+ + G+++SNHGGRQLD + ++ L + VA K V Sbjct: 243 WPHKLLVKGLLSAEDADRCIAEGADGVILSNHGGRQLDCAISPMEVLAQSVA--KTGKPV 300 Query: 277 YMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSG 336 +D G R G+D++KALALGA + LGR L+GLA +GE GV EVL +L A++ R + G Sbjct: 301 LIDSGFRRGSDIVKALALGAEAVLLGRATLYGLAARGETGVDEVLTLLKADIDRTLAQIG 360 Query: 337 CQSVAEISPDLIQ 349 C + +SPD +Q Sbjct: 361 CPDITSLSPDYLQ 373 >2J6X-A nrPDB Length = 374 Score = 404 bits (1038), Expect = e-113, Method: Composition-based stats. Identities = 122/346 (35%), Positives = 178/346 (51%), Gaps = 3/346 (0%) Query: 1 MPLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDT 60 + +V D + A K + +++I G + D T N A+K L PR +D+ DT Sbjct: 17 IDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDT 76 Query: 61 RTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAA 120 T I G +I AP ++P A H +A E TARA E IS+Y+ + E+I Sbjct: 77 STEILGHKIKAPFIMAPIAAHGLAHTTKEAGTARAVSEFGTIMSISAYSGATFEEISEGL 136 Query: 121 PEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLE--AN 178 G RWFQ+YM D N+ ++ A++ G A+++T D+ V GNR RD +N+ Sbjct: 137 NGGPRWFQIYMAKDDQQNRDILDEAKSDGATAIILTADSTVSGNRDRDVKNKFVYPFGMP 196 Query: 179 ILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKH 238 I+ + LR E ++ K D+ + + + LP+ +KGI EDA++A+K Sbjct: 197 IVQRYLRGTAEGMSLNNI-YGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKA 255 Query: 239 NVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARC 298 GI VSNHG RQL E S D L + V ++ + D GVR G V KALA GA Sbjct: 256 GASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADV 315 Query: 299 IFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEIS 344 + LGRP+L+GLA G G VLD +L R M L+G Q+V ++ Sbjct: 316 VALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLK 361 >6DVI-A nrPDB Length = 394 Score = 398 bits (1023), Expect = e-111, Method: Composition-based stats. Identities = 124/375 (33%), Positives = 190/375 (50%), Gaps = 31/375 (8%) Query: 4 VCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRTT 63 + AD++AHAQ+ L ++ G + D T N+ AFK L PR L ++ D Sbjct: 25 MSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVE 84 Query: 64 IQGQEISAPICISPTAFHSIAWPD--GEKSTARAAQEANICYVISSYASYSLEDIVAAAP 121 + G+ +AP+ +P ++ D G+ ++A+A+ + Y+ S+ A SLEDI A Sbjct: 85 LWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAG 144 Query: 122 EGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILL 181 + +FQLY D D + ++RAE G+ LVIT+DT + G R RD L + L Sbjct: 145 DTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRD----LTISNFPFL 200 Query: 182 KDL------------RALKEEKPTQS--------VPVSFPKASF----CWNDLSLLQSIT 217 + L + K ++ + F F W D+ ++SIT Sbjct: 201 RGLCLTNYVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSIT 260 Query: 218 RLPIILKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVY 277 ++P+ILKGI +DA A+ V GI SNHGGRQ + ++D L EVV A G V Sbjct: 261 KMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKA-SGDTPVL 319 Query: 278 MDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGC 337 D G+RTG DV+KALA+GA + +GRP WG A G G++ V L AE M + G Sbjct: 320 FDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGY 379 Query: 338 QSVAEISPDLIQFSR 352 +++ E++ D ++ +R Sbjct: 380 RNLKELTIDALRPTR 394 >2CDH-0 nrPDB Length = 226 Score = 288 bits (736), Expect = 3e-78, Method: Composition-based stats. Identities = 120/276 (43%), Positives = 164/276 (59%), Gaps = 50/276 (18%) Query: 61 RTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAA 120 TTI G +IS PI I+PTA +A P+GE +TARAA A +SS+A+ S+E++ + Sbjct: 1 TTTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTG 60 Query: 121 PEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANIL 180 P G R+FQLY+ D + Q+V+RAE GFKA+ +T+ Sbjct: 61 P-GIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTV----------------------- 96 Query: 181 LKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNV 240 W D++ LQ+IT LPI++KG++T EDA LA++H Sbjct: 97 --------------------------WKDVAWLQTITSLPILVKGVITAEDARLAVQHGA 130 Query: 241 QGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIF 300 GI+VSNHG RQLD V A+I AL EVV A +G+I V++DGGVR GTDV KALALGA +F Sbjct: 131 AGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGAAGVF 190 Query: 301 LGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSG 336 +GRP+++ LA +GE GVK+VL ++ E M LSG Sbjct: 191 IGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSG 226 >4N02-A nrPDB Length = 357 Score = 267 bits (682), Expect = 5e-72, Method: Composition-based stats. Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 50/322 (15%) Query: 52 LRDMSKVDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASY 111 L ++ ++D T G++ P I+ S + + A+ A+ I +V SY++ Sbjct: 56 LYNLDEIDLSTEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAA 115 Query: 112 SLEDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPV-LGNRRRDKR 170 L +D F+ + LG I +D PV LG + ++ Sbjct: 116 -----------------LKNPTDDSFSVKSSHPNLLLGTN---IGLDKPVELGLQTVEEM 155 Query: 171 NQLNLEANI-LLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTK 229 N + L+ ++ ++++L + E+ +S L+ +PI+LK + Sbjct: 156 NPVLLQVHVNVMQELLMPEGERKFRSWQS----------HLADYSKQIPVPIVLKEVGFG 205 Query: 230 EDA---ELAMKHNVQGIVVSNHGGRQLDEV----SASIDALREVVAAV----------KG 272 DA E A + V+ + +S GG + S D L + + K Sbjct: 206 MDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRRSGQRDYLNQWGQSTMQALLNAQEWKD 265 Query: 273 KIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCM 332 K+E+ + GGVR D++K L GA+ + L R +L + + V ++ A+L M Sbjct: 266 KVELLVSGGVRNPLDMIKCLVFGAKAVGLSRTVLELVETYTVEEVIGIVQGWKADLRLIM 325 Query: 333 TLSGCQSVAEISP-DLIQFSRL 353 C ++A++ D + + +L Sbjct: 326 CSLNCATIADLQKVDYLLYGKL 347 >3SR7-A nrPDB Length = 365 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 70/322 (21%), Positives = 131/322 (40%), Gaps = 52/322 (16%) Query: 53 RDMSKVDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYS 112 D++++D T GQ+ P I+ S + + A+ A + +V SY++ Sbjct: 69 YDLAEIDLSTHFAGQDFDFPFYINAMTGGSQKGKEVNEKLAQVADTCGLLFVTGSYSTA- 127 Query: 113 LEDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQ 172 +K+ D + Q V+++ A I +D P + + Q Sbjct: 128 ------------------LKNPDDTSYQ-VKKSRPHLLLATNIGLDKPYQAGLQAVRDLQ 168 Query: 173 -LNLEANI-LLKDLRALKEEKPTQSVPVSFPKASFCWN-DLSLLQSITRLPIILKGILTK 229 L L+ +I L+++L + E+ +S W LS +LP ILK + Sbjct: 169 PLFLQVHINLMQELLMPEGEREFRS-----------WKKHLSDYAKKLQLPFILKEVGFG 217 Query: 230 EDA---ELAMKHNVQGIVVSNHGGRQLDEVS-------ASIDALREVVAAV-------KG 272 D + A+ V+ + +S GG + + ++ + A V Sbjct: 218 MDVKTIQTAIDLGVKTVDISGRGGTSFAYIENRRGGNRSYLNQWGQTTAQVLLNAQPLMD 277 Query: 273 KIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCM 332 K+E+ GG+R D++KAL LGA+ + L R +L + V +++ +L M Sbjct: 278 KVEILASGGIRHPLDIIKALVLGAKAVGLSRTMLELVEQHSVHEVIAIVNGWKEDLRLIM 337 Query: 333 TLSGCQSVAEI-SPDLIQFSRL 353 CQ++AE+ + D + + RL Sbjct: 338 CALNCQTIAELRNVDYLLYGRL 359 >1P0K-A nrPDB Length = 349 Score = 145 bits (365), Expect = 3e-35, Method: Composition-based stats. Identities = 57/312 (18%), Positives = 117/312 (37%), Gaps = 49/312 (15%) Query: 55 MSKVDTRTTIQGQEISAPICISPTAFHSIAWP-DGEKSTARAAQEANICYVISSYASYSL 113 + +VD T I S+PI I+ + KS ARAA +A I + S S Sbjct: 40 LEQVDISTKIGELSSSSPIFINAMTGGGGKLTYEINKSLARAASQAGIPLAVGSQMSA-- 97 Query: 114 EDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQL 173 L S+ + ++V++ G + + + + Sbjct: 98 ---------------LKDPSER-LSYEIVRKENPNGLIFANLGSEATAAQAKEAVEMIGA 141 Query: 174 N-LEANI-LLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKED 231 N L+ ++ +++++ + ++ + + S +P+I+K + Sbjct: 142 NALQIHLNVIQEIVMPEGDRSFSGAL----------KRIEQICSRVSVPVIVKEVGFGMS 191 Query: 232 ---AELAMKHNVQGIVVSNHGGRQLDEVS--------ASIDALREVVAAVKGKIE----- 275 A + + + +GG ++ + ++ AA +I Sbjct: 192 KASAGKLYEAGAAAVDIGGYGGTNFSKIENLRRQRQISFFNSWGISTAASLAEIRSEFPA 251 Query: 276 --VYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMT 333 + GG++ DV KA+ALGA C + L L GE+G+ E + ++ EL MT Sbjct: 252 STMIASGGLQDALDVAKAIALGASCTGMAGHFLKALTDSGEEGLLEEIQLILEELKLIMT 311 Query: 334 LSGCQSVAEISP 345 + G +++A++ Sbjct: 312 VLGARTIADLQK 323 >2ZRW-A nrPDB Length = 368 Score = 108 bits (270), Expect = 3e-24, Method: Composition-based stats. Identities = 56/322 (17%), Positives = 111/322 (34%), Gaps = 48/322 (14%) Query: 53 RDMSKVDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYS 112 S+++T+T +EIS P+ ++ K A A++ I + S Sbjct: 42 ISFSEINTKTKFFRKEISVPVMVTGMTGGRNELGRINKIIAEVAEKFGIPMGVGS----- 96 Query: 113 LEDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQ 172 + + E F + V++ + + V G ++ ++ Sbjct: 97 -QRVAIEKAEARESFAI------------VRKVAPTIPIIANLGMPQLVKGYGLKEFQDA 143 Query: 173 LNLEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTK--- 229 + + + +E + + L + +PII+K Sbjct: 144 IQMIEADAIAVHLNPAQEVFQPEGEPEYQIYAL--EKLRDISKELSVPIIVKESGNGISM 201 Query: 230 EDAELAMKHNVQGIVVSNHGGRQ-----------------------LDEVSASIDALREV 266 E A+L + ++ S GG LD + ++ EV Sbjct: 202 ETAKLLYSYGIKNFDTSGQGGTNWIAIEMIRDIRRGNWKAESAKNFLDWGVPTAASIMEV 261 Query: 267 VAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTA 326 +V + GG+R+G D KA+ALGA + P+L A +G++ +++ + Sbjct: 262 RYSVPDSF-LVGSGGIRSGLDAAKAIALGADIAGMALPVLKS-AIEGKESLEQFFRKIIF 319 Query: 327 ELHRCMTLSGCQSVAEISPDLI 348 EL M L+G + V + I Sbjct: 320 ELKAAMMLTGSKDVDALKKTSI 341 >3DH7-A nrPDB Length = 332 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 69/343 (20%), Positives = 116/343 (33%), Gaps = 52/343 (15%) Query: 24 FIEGEADDGITYSENIAAFKRIRLRPRYL--RDMSKVDTRTTIQGQEISAPICISPTAFH 81 +E + + Y + + RLR + L +S+VD T G+ + AP I Sbjct: 10 HLEACLEGEVAYQKTTTGLEGFRLRYQALAGLALSEVDLTTPFLGKTLKAPFLIGAMTGG 69 Query: 82 SIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPEGFRWFQLYMKSDWDFNKQM 141 + A AA+ + ++ S I+ PE R F+ Sbjct: 70 EENGERINLALAEAAEALGVGMMLGS------GRILLERPEALRSFR------------- 110 Query: 142 VQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRALKEEKPTQSVPVSFP 201 V++ + L RR R+ L +L D A ++V Sbjct: 111 VRKVAPKALLIANLG-----LAQLRRYGRDDLLRLVEMLEADALAFHVNPLQEAVQRGDT 165 Query: 202 KASFCWNDLSLLQSITRLPIILKGILTKEDAELAM---KHNVQGIVVSNHGGRQLD---- 254 L+ L + P+++K + E A+ + + V+ GG Sbjct: 166 DFRGLVERLAELLPL-PFPVMVKEVGHGLSREAALALRDLPLAAVDVAGAGGTSWARVEE 224 Query: 255 ---------------EVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCI 299 + + L V V + + GGV TGTD KALALGA + Sbjct: 225 WVRFGEVRHPELCEIGIPTARAILE--VREVLPHLPLVASGGVYTGTDGAKALALGADLL 282 Query: 300 FLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAE 342 + RP+L A +G + V + EL + G ++ E Sbjct: 283 AVARPLLRP-ALEGAERVAAWIGDYLEELRTALFAIGARNPKE 324 >3FFS-A nrPDB Length = 400 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 52/289 (17%), Positives = 104/289 (35%), Gaps = 19/289 (6%) Query: 42 FKRIRLRPRYLRDM-SKVDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEAN 100 F+ I L P Y + +V T + +S I + +A ++ E A Sbjct: 12 FEDILLVPNYSEVLPREVSLETK-LTKNVSLKIPLISSAMDTVT----EHLMAVGMARLG 66 Query: 101 ICYVISSYASYSLEDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKA-LVITIDT 159 +I + + +E V + W ++ + Q + + G ID Sbjct: 67 GIGII--HKNMDMESQVNEVLKVKNWIS-NLEKNESTPDQNLDKESTDGKDTKSNNNIDA 123 Query: 160 PVLGNRRRDKRNQL--NLEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSIT 217 N R ++ + N + + ++ + + + L ++S Sbjct: 124 YSNENLDNKGRLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKM 183 Query: 218 RLPIILKGILTKEDAELAMKHNVQGIVVS-NHGG----RQLDEVSASIDALREVVAAVKG 272 + +I+ ++T+E + +++ GI V G R + V E ++V Sbjct: 184 NIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVAS 243 Query: 273 K--IEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKE 319 K I + DGG+R D+ KALA+GA + +G + GE + Sbjct: 244 KFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIG 292 >4QJ1-A nrPDB Length = 361 Score = 51.7 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 61/152 (40%), Gaps = 7/152 (4%) Query: 175 LEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAEL 234 + N + + ++ + + + L ++S + +I+ ++T+E + Sbjct: 102 IGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKE 161 Query: 235 AMKHNVQGIVVS-NHGG----RQLDEVSASIDALREVVAAVKGK--IEVYMDGGVRTGTD 287 +++ GI V G R + V E ++V K I + DGG+R D Sbjct: 162 LIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGD 221 Query: 288 VLKALALGARCIFLGRPILWGLACKGEDGVKE 319 + KALA+GA + +G + GE + Sbjct: 222 IGKALAVGASSVMIGSILAGTEESPGEKELIG 253 >1VRD-A nrPDB Length = 494 Score = 50.5 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 31/132 (23%), Positives = 48/132 (36%), Gaps = 22/132 (16%) Query: 219 LPIILKGILTKEDAELAMKHNVQGI-------------VVSNHGGRQLDEVSASIDALRE 265 LP++ + T E E +K + VV+ G QL V + Sbjct: 279 LPVVAGNVATPEGTEALIKAGADAVKVGVGPGSICTTRVVAGVGVPQLTAVMECSEV--- 335 Query: 266 VVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILT 325 A K + + DGG+R D++KALA GA + +G GE + Sbjct: 336 ---ARKYDVPIIADGGIRYSGDIVKALAAGAESVMVGSIFAGTEEAPGETILY---QGRK 389 Query: 326 AELHRCMTLSGC 337 + +R M G Sbjct: 390 YKAYRGMGSLGA 401 >4MJM-A nrPDB Length = 385 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 46/218 (21%), Positives = 84/218 (38%), Gaps = 32/218 (14%) Query: 140 QMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRALKEEKPTQSVPVS 199 V+R+E+ G K + I+ P N +DK+ +L + A + + + + ++ + Sbjct: 89 DKVKRSESGGIKDIEKVIEFP---NSAKDKQGRLLVGAAVGVTADAMTRIDALVKASVDA 145 Query: 200 FP------KASFCWNDLSLLQSITR-LPIILKGILTKEDAELAMKHNVQGI--------- 243 + + + +++ L II + T E + ++ + Sbjct: 146 IVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVKVGIGPGSI 205 Query: 244 ----VVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCI 299 VV+ G QL +A D A K I V DGG++ D++KALA GA + Sbjct: 206 CTTRVVAGVGVPQL---TAVYDC---ATEARKHGIPVIADGGIKYSGDMVKALAAGAHVV 259 Query: 300 FLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGC 337 LG GE E+ +++R M G Sbjct: 260 MLGSMFAGVAESPGET---EIYQGRQFKVYRGMGSVGA 294 >3TSB-A nrPDB Length = 511 Score = 47.8 bits (112), Expect = 8e-06, Method: Composition-based stats. Identities = 34/142 (23%), Positives = 54/142 (38%), Gaps = 23/142 (16%) Query: 210 LSLLQSITR-LPIILKGILTKEDAELAMKHNVQGI-------------VVSNHGGRQLDE 255 + +++ L II + T E + ++ + VV+ G QL Sbjct: 288 VKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQL-- 345 Query: 256 VSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGED 315 +A D A K I V DGG++ D++KALA GA + LG GE Sbjct: 346 -TAVYDC---ATEARKHGIPVIADGGIKYSGDMVKALAAGAHVVMLGSMFAGVAESPGET 401 Query: 316 GVKEVLDILTAELHRCMTLSGC 337 E+ +++R M G Sbjct: 402 ---EIYQGRQFKVYRGMGSVGA 420 >1JCN-A nrPDB Length = 514 Score = 47.4 bits (111), Expect = 9e-06, Method: Composition-based stats. Identities = 38/160 (23%), Positives = 62/160 (38%), Gaps = 19/160 (11%) Query: 163 GNRRRDK-RNQLNLEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPI 221 G R DK R L +A + + L + + Q V + K Q L + Sbjct: 251 GTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIK-----------QKYPHLQV 299 Query: 222 ILKGILTKEDAELAMKHNVQGIVVSNHGG----RQ--LDEVSASIDALREVVAAVKG-KI 274 I ++T A+ + V G+ V G Q + A+ +V + + Sbjct: 300 IGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGV 359 Query: 275 EVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 + DGG++T V+KALALGA + +G + GE Sbjct: 360 PIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGE 399 >2GJN-A nrPDB Length = 328 Score = 47.1 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 32/181 (17%), Positives = 62/181 (34%), Gaps = 16/181 (8%) Query: 173 LNLEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILK--GILTKE 230 L + + + RA E + V + ++ + + +I K + Sbjct: 77 LPTQKPVPYAEYRAAIIEAGIRVVETAGNDPG---EHIAEFRRH-GVKVIHKCTAVRHAL 132 Query: 231 DAEL--AMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDV 288 AE ++ G + H G D++ + L + ++ + GG G + Sbjct: 133 KAERLGVDAVSIDGFECAGHPGE--DDIPG-LVLLPAAANRL--RVPIIASGGFADGRGL 187 Query: 289 LKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTA-ELHRCMTLSGCQSVAEISPDL 347 + ALALGA I +G L C VK + M ++ A ++ + Sbjct: 188 VAALALGADAINMGTRFLATRECPIHPAVKAAIRAADERSTDLIMRSL--RNTARVARNA 245 Query: 348 I 348 I Sbjct: 246 I 246 >4FXS-A nrPDB Length = 496 Score = 47.1 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 45/119 (37%), Gaps = 20/119 (16%) Query: 210 LSLLQSITRLPIILKG-ILTKEDAELAMKHNVQGI-------------VVSNHGGRQLDE 255 + ++ I+ G + T E A ++ V + +V+ G Q+ Sbjct: 263 IRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITA 322 Query: 256 VSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 ++ + E I V DGG+R D+ KA+A GA C+ +G GE Sbjct: 323 IADAAGVANEYG------IPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGE 375 >6I0M-A nrPDB Length = 517 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 25/113 (22%), Positives = 44/113 (38%), Gaps = 8/113 (7%) Query: 210 LSLLQSITR-LPIILKGILTKEDAELAMKHNVQGIVVSNHGG----RQ--LDEVSASIDA 262 + ++ L +I ++T A+ + V + V G Q L A Sbjct: 290 IKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATA 349 Query: 263 LREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 + +V + + V DGG++ + KALALGA + +G + GE Sbjct: 350 VYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 402 >4FEZ-A nrPDB Length = 388 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 45/119 (37%), Gaps = 20/119 (16%) Query: 210 LSLLQSITRLPIILKG-ILTKEDAELAMKHNVQGI-------------VVSNHGGRQLDE 255 + ++ I+ G + T E A ++ V + +V+ G Q+ Sbjct: 162 IRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITA 221 Query: 256 VSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 ++ + E I V DGG+R D+ KA+A GA C+ +G GE Sbjct: 222 IADAAGVANEYG------IPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGE 274 >5LSM-A nrPDB Length = 359 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 53/265 (20%), Positives = 82/265 (30%), Gaps = 28/265 (10%) Query: 69 ISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLE----DIVAAAPEGF 124 I PI +P A + + A A EA + A SLE ++ A + Sbjct: 11 IEFPIIQAPMAGVQGS------ALAIAVSEAGGLGSLPC-AMLSLEALEAELTAIRSQTA 63 Query: 125 RWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQ---LNLEANILL 181 + + + Q ++A L A P D Q Sbjct: 64 KPINVNFFCHREPVAQAAKQAAWLEQLA-------PYFAEFNLDPNAQPAGAQRTPYSKA 116 Query: 182 KDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQ 241 + K + S P S + ++ L E A A Q Sbjct: 117 QAEVLAKFKPEVVSFHFGLPDEELLLEIKSWGSKVISTATTVEEALWLE-ARGADAIIAQ 175 Query: 242 GIVVSNHGG----RQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGAR 297 G+ H G L E + L +++AAV+ I V GG+ T V A+ +GA Sbjct: 176 GLEAGGHRGHFLSEDLTEQLGTFSLLPQIIAAVE--IPVIAAGGIVDATTVRAAMTMGAS 233 Query: 298 CIFLGRPILWGLACKGEDGVKEVLD 322 + +G L C +E L Sbjct: 234 AVQVGTAYLLCPECNTSAIHREALQ 258 >4Z87-A nrPDB Length = 525 Score = 45.1 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 44/113 (38%), Gaps = 8/113 (7%) Query: 210 LSLLQSITR-LPIILKGILTKEDAELAMKHNVQGIVVSNHGG----RQ--LDEVSASIDA 262 + ++ L +I ++T+E A + G+ + G Q + A Sbjct: 293 IKWIKETFPDLQVIAGNVVTREQAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTA 352 Query: 263 LREVVA-AVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 + V A + + DGGV+ + KA+ALGA + +G + GE Sbjct: 353 VYNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMMGGMLAGTTESPGE 405 >4XTI-A nrPDB Length = 413 Score = 45.1 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 44/113 (38%), Gaps = 8/113 (7%) Query: 210 LSLLQSITR-LPIILKGILTKEDAELAMKHNVQGIVVSNHGG----RQ--LDEVSASIDA 262 + ++ L +I ++T+E A + G+ + G Q + A Sbjct: 181 IKWIKETFPDLQVIAGNVVTREQAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTA 240 Query: 263 LREVVA-AVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 + V A + + DGGV+ + KA+ALGA + +G + GE Sbjct: 241 VYNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMMGGMLAGTTESPGE 293 >1ZFJ-A nrPDB Length = 491 Score = 45.1 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 29/123 (23%), Positives = 49/123 (39%), Gaps = 14/123 (11%) Query: 208 NDLSLLQSITRLPIILKG-ILTKEDAELAMKHNVQ--------GIVVSNH--GGRQLDEV 256 ++ +++ ++ G I T E A V G + + G + +V Sbjct: 263 RKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQV 322 Query: 257 SASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDG 316 +A DA VA GK + DGG++ D++KALA G + LG GE Sbjct: 323 TAIYDA--AAVAREYGKT-IIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETE 379 Query: 317 VKE 319 + + Sbjct: 380 IYQ 382 >4DQW-A nrPDB Length = 509 Score = 44.4 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 4/90 (4%) Query: 258 ASIDALREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDG 316 I A+ V AA++G + + DGG+R D+ KA+ GA C+ +G GE Sbjct: 335 PQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMFAGTEEAPGE-- 392 Query: 317 VKEVLDILTAELHRCMTLSGCQSVAEISPD 346 E+ + + +R M G S ++ S D Sbjct: 393 -IELFQGRSYKSYRGMGSLGAMSGSQGSSD 421 >5AHL-A nrPDB Length = 400 Score = 44.0 bits (102), Expect = 9e-05, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 4/90 (4%) Query: 258 ASIDALREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDG 316 I A+ V AA++G + + DGG+R D+ KA+ GA C+ +G GE Sbjct: 226 PQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMFAGTEEAPGE-- 283 Query: 317 VKEVLDILTAELHRCMTLSGCQSVAEISPD 346 E+ + + +R M G S ++ S D Sbjct: 284 -IELFQGRSYKSYRGMGSLGAMSGSQGSSD 312 >2GGG-A nrPDB Length = 375 Score = 44.0 bits (102), Expect = 9e-05, Method: Composition-based stats. Identities = 32/195 (16%), Positives = 63/195 (32%), Gaps = 24/195 (12%) Query: 64 IQGQEISAPICISPTAFHSIAWPDGEKSTARAA-----QEANICYVISSYASYSLEDIVA 118 I GQ + P +S AA + + + + E + Sbjct: 82 ILGQTFANPEAVSDALGSYRGNRMARAMVEMAAWDLWARTLGVP--LGTLLGGHKEQVEV 139 Query: 119 AAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITID-----TPVLGNRRRDKRNQL 173 G + +D +V+R G++ + + I PV R +L Sbjct: 140 GVSLGIQ-------ADEQATVDLVRRHVEQGYRRIKLKIKPGWDVQPVRATREAFPDIRL 192 Query: 174 NLEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDL---SLLQSITRLPIILKG-ILTK 229 ++AN L + +++ + W+DL + L R P+ L + + Sbjct: 193 TVDAN-SAYTLADAGRLRQLDEYDLTYIEQPLAWDDLVDHAELARRIRTPLCLDESVASA 251 Query: 230 EDAELAMKHNVQGIV 244 DA A+ G++ Sbjct: 252 SDARKALALGAGGVI 266 Score = 30.9 bits (68), Expect = 0.83, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 31/77 (40%), Gaps = 8/77 (10%) Query: 231 DAELAMKHNVQGIVVSNHGGRQLD-----EVSASI---DALREVVAAVKGKIEVYMDGGV 282 D L + N + RQLD + + D + A + + + +D V Sbjct: 189 DIRLTVDANSAYTLADAGRLRQLDEYDLTYIEQPLAWDDLVDHAELARRIRTPLCLDESV 248 Query: 283 RTGTDVLKALALGARCI 299 + +D KALALGA + Sbjct: 249 ASASDARKALALGAGGV 265 >4AF0-B nrPDB Length = 556 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 46/115 (40%), Gaps = 12/115 (10%) Query: 210 LSLLQSITR-LPIILKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDAL--REV 266 + ++ + +I ++T+E A + G+ + G + ++ + A+ + Sbjct: 313 IKWIKQTYPKIDVIAGNVVTREQAAQLIAAGADGLRI-GMGSGSI-CITQEVMAVGRPQG 370 Query: 267 VA-------AVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 A A + I DGG+ + KALALGA + +G + GE Sbjct: 371 TAVYAVAEFASRFGIPCIADGGIGNIGHIAKALALGASAVMMGGLLAGTTESPGE 425 >5UQG-A nrPDB Length = 406 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%) Query: 258 ASIDALREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLG 302 I A+ E V + V DGG++ D+ KALA+GA + +G Sbjct: 233 PQISAIDECVEEANKFGVPVIADGGIKYSGDIAKALAVGASSVMIG 278 >1YPF-A nrPDB Length = 336 Score = 42.0 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 37/122 (30%), Gaps = 25/122 (20%) Query: 210 LSLLQSITRLPIILKG-ILTKEDAELAMKHNVQGIVVS---------------NHGGRQL 253 + ++ ++ G + T E V GG QL Sbjct: 140 IQHIKKHLPESFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQL 199 Query: 254 DEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKG 313 ALR A + DGG+RT DV K++ GA + +G G Sbjct: 200 A-------ALRWCAKAASK--PIIADGGIRTNGDVAKSIRFGATMVMIGSLFAGHEESPG 250 Query: 314 ED 315 E Sbjct: 251 ET 252 >5UPU-A nrPDB Length = 407 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 23/60 (38%) Query: 255 EVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 L V A + V DGG++ D+ KALA GA LG + GE Sbjct: 228 GAPQITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAGASTAMLGSLLAGTAEAPGE 287 >2CU0-A nrPDB Length = 486 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 53/149 (35%), Gaps = 11/149 (7%) Query: 175 LEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAEL 234 + + + + K V + + ++ I+ I + + Sbjct: 225 VSPFDIKRAIELDKAGVDVIVVDTAHAHNLKAIKSMKEMRQKVDADFIVGNIANPKAVDD 284 Query: 235 -----AMKHNVQ-GIVVSNHGGRQLDEV-SASIDALREVVAAVKG-KIEVYMDGGVRTGT 286 A+K + G + + R + V I A+ V + + V DGG+R Sbjct: 285 LTFADAVKVGIGPGSICTT---RIVAGVGVPQITAVAMVADRAQEYGLYVIADGGIRYSG 341 Query: 287 DVLKALALGARCIFLGRPILWGLACKGED 315 D++KA+A GA + LG + G++ Sbjct: 342 DIVKAIAAGADAVMLGNLLAGTKEAPGKE 370 >4Q4K-A nrPDB Length = 357 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 55/279 (19%), Positives = 92/279 (32%), Gaps = 27/279 (9%) Query: 58 VDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIV 117 D T + G I PI +P S + A + S A I Sbjct: 2 TDRFTRLLG--IQQPIIQAPMLGVSTPAL---AAAVSNAGGLGSIAITGSAAEKGRALIR 56 Query: 118 AAAPEGFRWFQLYMK-SDWDFNKQMVQRAEALGFKALV--ITIDTPVLGNRRRDKRNQLN 174 + F + + +RA K L + PV R ++ Sbjct: 57 EVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPV---RLKNIYLSFL 113 Query: 175 LEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAEL 234 + + L L EE+P VSF + + + LQ++ + +++ T E+A L Sbjct: 114 EDPTL----LPMLLEERP---AAVSFHFGAPPRDQVRALQAV-GIRVLVCAT-TPEEAAL 164 Query: 235 AMKHNVQGIVVSN------HGGRQLDEVSASIDALREV-VAAVKGKIEVYMDGGVRTGTD 287 +V G + + A+I L V + A +G + V GG+ G Sbjct: 165 VEAAGADAVVAQGIEAGGHRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRG 224 Query: 288 VLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTA 326 + AL LGA + +G + +E L A Sbjct: 225 IRAALELGASAVQMGTAFVLCPESSANAAYREALKGPRA 263 >1TYG-A nrPDB Length = 253 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 31/78 (39%) Query: 228 TKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTD 287 T +D LA K G+ G + ++ L + K+ V +D G+ + D Sbjct: 131 TSDDVVLARKLEELGVHAIMPGASPIGSGQGILNPLNLSFIIEQAKVPVIVDAGIGSPKD 190 Query: 288 VLKALALGARCIFLGRPI 305 A+ LGA + L + Sbjct: 191 AAYAMELGADGVLLNTAV 208 Score = 35.1 bits (79), Expect = 0.046, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 44/110 (40%), Gaps = 18/110 (16%) Query: 138 NKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRALKEEKPTQSVP 197 + ++ GF L T D VL + + L + ++ + P Sbjct: 113 TLKASEQLLEEGFIVLPYTSDDVVLARKLEE------LGVHAIMPG-----------ASP 155 Query: 198 VSFPKASFCWNDLSLLQSITRLPIILK-GILTKEDAELAMKHNVQGIVVS 246 + + +LS + ++P+I+ GI + +DA AM+ G++++ Sbjct: 156 IGSGQGILNPLNLSFIIEQAKVPVIVDAGIGSPKDAAYAMELGADGVLLN 205 >3R2G-A nrPDB Length = 361 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 276 VYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 + DGG++T D++KALA GA + +G + GE Sbjct: 202 IVADGGIKTSGDIVKALAFGADFVMIGGMLAGSAPTPGE 240 >3OIX-A nrPDB Length = 345 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 42/98 (42%), Gaps = 9/98 (9%) Query: 246 SNHGGRQLDEV-SASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRP 304 + GG D V ++ + + I++ GGV+TG D + + GA + +G Sbjct: 247 NGFGGIGGDYVKPTALANVHAFYKRLNPSIQIIGTGGVKTGRDAFEHILCGASMVQIG-- 304 Query: 305 ILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAE 342 ++G ++ +T EL MT G +++ + Sbjct: 305 -----TALHQEG-PQIFKRITKELKAIMTEKGYETLED 336 >1UUO-A nrPDB Length = 372 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 51/217 (23%), Positives = 84/217 (38%), Gaps = 20/217 (9%) Query: 130 YMKSDWDFNKQMVQRAEALGFKA--LVITIDTP-VLGNRRRDKRNQLNLEANILLKDLRA 186 K+ D + LG A LV+ + +P G R + +L + +L++ A Sbjct: 160 KNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDA 219 Query: 187 LKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQGIVVS 246 LK + + D + S+ R I I+T + +QG + S Sbjct: 220 LKGTRKPAVLVK--IAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPV--GLQGALRS 275 Query: 247 NHGGRQLDEVSA-SIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCI------ 299 GG + S +RE+ A +G+I + GGV +G D L+ + GA + Sbjct: 276 ETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 335 Query: 300 -FLGRPIL-----WGLACKGEDGVKEVLDILTAELHR 330 FLG P++ A E G V D + A+ R Sbjct: 336 IFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR 372 >5Z9Y-A nrPDB Length = 252 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 62/173 (35%), Gaps = 30/173 (17%) Query: 87 DGEKSTARAAQEANICYVISSYASYSLEDIV-----AAAPEGFRWFQLYMKSDWDF---- 137 DG I + ++ S S + V A W +L + +D Sbjct: 52 DGGTGLLDLLNRLGITPLPNTAGSRSAAEAVLTAQLAREALNTNWVKLEVIADERTLWPD 111 Query: 138 NKQMVQRAEAL---GFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRALKEEKPTQ 194 ++V+ AE L GF L T D PVL R D + Sbjct: 112 AVELVRAAEQLVDDGFVVLPYTTDDPVLARRLEDTGCAAVMPLG---------------- 155 Query: 195 SVPVSFPKASFCWNDLSLLQSITRLPIILK-GILTKEDAELAMKHNVQGIVVS 246 P+ +++ ++ + R+P++L GI T DA LAM+ ++++ Sbjct: 156 -SPIGTGLGIANPHNIEMIVAGARVPVVLDAGIGTASDAALAMELGCDAVLLA 207 Score = 32.4 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 17/33 (51%) Query: 273 KIEVYMDGGVRTGTDVLKALALGARCIFLGRPI 305 ++ V +D G+ T +D A+ LG + L + Sbjct: 178 RVPVVLDAGIGTASDAALAMELGCDAVLLASAV 210 >1EEP-A nrPDB Length = 404 Score = 37.8 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 57/285 (20%), Positives = 107/285 (37%), Gaps = 35/285 (12%) Query: 42 FKRIRLRPRYLRDM-SKVDTRTTIQGQ-EISAPICISPTAFHSIAWPDGEKSTARAAQEA 99 F + L PR + S+V +T + ++ P S + E A A + Sbjct: 12 FDDVSLIPRKSSVLPSEVSLKTQLTKNISLNIPFLSSAMDTVT------ESQMAIAIAKE 65 Query: 100 NICYVISSYASYSLEDIVAAAPEGFRW-FQLYMKSDWDFNKQM-------VQRAEALGFK 151 +I + + S+E + + FQ + ++ D N+Q ++ +K Sbjct: 66 GGIGII--HKNMSIEAQRKEIEKVKTYKFQKTINTNGDTNEQKPEIFTAKQHLEKSDAYK 123 Query: 152 ALVITIDTPVLGNRRRDKRNQLNLEANI------LLKDLRALKEEKPTQSVPVSFPKASF 205 D P N +D N+L + A + + + +K + + ++ Sbjct: 124 NAEHKEDFP---NACKDLNNKLRVGAAVSIDIDTIERVEELVKAHVDILVIDSAHGHSTR 180 Query: 206 CWNDLSLLQSITR-LPIILKGILTKEDAELAMKHNVQGIVVS-NHGG----RQLDEV-SA 258 + +++ L +I I+TKE A + + V G R + V Sbjct: 181 IIELIKKIKTKYPNLDLIAGNIVTKEAALDLISVGADCLKVGIGPGSICTTRIVAGVGVP 240 Query: 259 SIDALREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLG 302 I A+ +V A I + DGG+R DV+KA+A GA + +G Sbjct: 241 QITAICDVYEACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIG 285 >2H6R-A nrPDB Length = 219 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 27/58 (46%), Gaps = 2/58 (3%) Query: 267 VAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDIL 324 V + ++V G+ G DV AL LGA + L ++ E+ ++E++ + Sbjct: 164 VKEINKDVKVLCGAGISKGEDVKAALDLGAEGVLLASGVVKAKNV--EEAIRELIKFI 219 >2C6Q-A nrPDB Length = 351 Score = 37.0 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 38/115 (33%), Gaps = 12/115 (10%) Query: 210 LSLLQSITR-LPIILKGILTKEDAELAMKHNVQ--------GIVVSNHGGRQLDEVSASI 260 + ++ I+ ++T E E + G V + + + Sbjct: 152 VKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGY--PQL 209 Query: 261 DALREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 A+ E A G K + DGG DV KA GA + LG + GE Sbjct: 210 SAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGE 264 >1JUE-A nrPDB Length = 311 Score = 37.0 bits (84), Expect = 0.013, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 247 NHGGRQLDEV-SASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPI 305 GG + ++ +R +K +I++ GG+ TG D + L GA + +G Sbjct: 215 GFGGIGGAYIKPTALANVRAFYTRLKPEIQIIGTGGIETGQDAFEHLLCGATMLQIG--- 271 Query: 306 LWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAE 342 L +G + D + EL M G QS+A+ Sbjct: 272 -TALHKEGPA----IFDRIIKELEEIMNQKGYQSIAD 303 >6I4B-A nrPDB Length = 405 Score = 36.7 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 63/154 (40%), Gaps = 32/154 (20%) Query: 212 LLQSITRLPII-------LKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSA------ 258 + + P++ L KE A++ ++ N+ G+++SN Q++++ + Sbjct: 252 WFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISN-TTTQINDIKSFENKKG 310 Query: 259 ----------SIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 S + E+ +I + GG+ +G D L+ + GA L +++ Sbjct: 311 GVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSCLVF- 369 Query: 309 LACKGEDGVKEVLDILTAELHRCMTLSGCQSVAE 342 +G+K + + EL+ + G ++ E Sbjct: 370 ------NGMKSAVQ-IKRELNHLLYQRGYYNLKE 396 >1TV5-A nrPDB Length = 443 Score = 36.7 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 63/154 (40%), Gaps = 32/154 (20%) Query: 212 LLQSITRLPII-------LKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSA------ 258 + + P++ L KE A++ ++ N+ G+++SN Q++++ + Sbjct: 290 WFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISN-TTTQINDIKSFENKKG 348 Query: 259 ----------SIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 S + E+ +I + GG+ +G D L+ + GA L +++ Sbjct: 349 GVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSCLVF- 407 Query: 309 LACKGEDGVKEVLDILTAELHRCMTLSGCQSVAE 342 +G+K + + EL+ + G ++ E Sbjct: 408 ------NGMKSAVQ-IKRELNHLLYQRGYYNLKE 434 >6HYE-A nrPDB Length = 314 Score = 36.3 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 25/55 (45%), Gaps = 4/55 (7%) Query: 256 VSASIDALREVVAAVKGKIEV--YMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 +SA D + + G++ V + GG+ T D + LG +F+G + G Sbjct: 210 ISAPYDLVAQTKQ--MGRVPVVQFASGGITTPADAALMMQLGCDGVFVGSEVFDG 262 >4JDY-A nrPDB Length = 264 Score = 36.3 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 29/73 (39%) Query: 255 EVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 E+ A + + EV A K + ++ GG+ T D + LGA +F+G I A + Sbjct: 183 ELQAPYELVAEVARAGKLPVTLFTAGGIATPADAAMMMQLGAEGVFVGSGIFKSGAPEHR 242 Query: 315 DGVKEVLDILTAE 327 + Sbjct: 243 AAAIVKATTFFDD 255 >2BWG-A nrPDB Length = 367 Score = 36.3 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 40/115 (34%), Gaps = 12/115 (10%) Query: 210 LSLLQSITR-LPIILKGILTKEDAELAMKHNVQ--------GIVVSNHGGRQLDEVSASI 260 + L+++ I+ ++T E E + G V + + + Sbjct: 164 VKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGY--PQL 221 Query: 261 DALREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 314 A+ E + G K + DGG DV KA GA + LG C GE Sbjct: 222 SAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGE 276 >3T55-A nrPDB Length = 272 Score = 35.1 bits (79), Expect = 0.042, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 3/78 (3%) Query: 225 GILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRT 284 + T+++A+ A+K + I V+ R L + D + + + + GVR Sbjct: 168 EVHTEQEADRALKAGAKVIGVN---ARDLMTLDVDRDCFARIAPGLPSSVIRIAESGVRG 224 Query: 285 GTDVLKALALGARCIFLG 302 D+L GA + +G Sbjct: 225 TADLLAYAGAGADAVLVG 242 >1MZH-A nrPDB Length = 225 Score = 35.1 bits (79), Expect = 0.047, Method: Composition-based stats. Identities = 29/186 (15%), Positives = 66/186 (35%), Gaps = 26/186 (13%) Query: 139 KQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRALKEEKPTQSVPV 198 ++ V ++E LG A+ + L + K + L + ++K ++ ++V Sbjct: 23 EEFVLKSEELGIYAVCVNPYHVKLASSIAKKVKVCCVIGFPLGLNKTSVKVKEAVEAVRD 82 Query: 199 SFPKASFCW--------------NDLSLLQSITR---LPIILKGILTKED-----AELAM 236 + W +L + T +I++ E+ E+ + Sbjct: 83 GAQELDIVWNLSAFKSEKYDFVVEELKEIFRETPSAVHKVIVETPYLNEEEIKKAVEICI 142 Query: 237 KHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGA 296 + I S +++ +R + ++ KG+I+V GG+R + + GA Sbjct: 143 EAGADFIKTS----TGFAPRGTTLEEVRLIKSSAKGRIKVKASGGIRDLETAISMIEAGA 198 Query: 297 RCIFLG 302 I Sbjct: 199 DRIGTS 204 >1HG3-A nrPDB Length = 225 Score = 35.1 bits (79), Expect = 0.048, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 34/101 (33%), Gaps = 25/101 (24%) Query: 233 ELAMKHNVQGIVVSNHGGRQLDEVSASIDALR-------------------------EVV 267 A + + +V SN+ + + D + E+V Sbjct: 111 RRAEEVGLMTMVCSNNPAVSAAVAALNPDYVAVEPPELIGTGIPVSKAKPEVITNTVELV 170 Query: 268 AAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 V +++V G+ TG DV KA+ LG + L + Sbjct: 171 KKVNPEVKVLCGAGISTGEDVKKAIELGTVGVLLASGVTKA 211 Score = 28.6 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 13/107 (12%) Query: 142 VQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRALKEEKPTQSVPVSFP 201 ++RAE +G +V + + V + + +E +L +PVS Sbjct: 110 IRRAEEVGLMTMVCSNNPAVSAAVAALNPDYVAVEPP----ELIGTG-------IPVSKA 158 Query: 202 KASFCWNDLSLLQSITRLPIIL--KGILTKEDAELAMKHNVQGIVVS 246 K N + L++ + +L GI T ED + A++ G++++ Sbjct: 159 KPEVITNTVELVKKVNPEVKVLCGAGISTGEDVKKAIELGTVGVLLA 205 >3U2O-A nrPDB Length = 395 Score = 35.1 bits (79), Expect = 0.051, Method: Composition-based stats. Identities = 43/203 (21%), Positives = 83/203 (40%), Gaps = 11/203 (5%) Query: 130 YMKSDWDFNKQMVQRAEALGFKA--LVITIDTP-VLGNRRRDKRNQLNLEANILLKDLRA 186 K+ D + + LG A LV+ + +P G R + +L +L++ Sbjct: 183 KNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDG 242 Query: 187 LKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQGIVVS 246 L+ + + + D + S+ + + + G++ + ++ +QG + S Sbjct: 243 LR--RVHRPAVLVKIAPDLTSQDKEDIASVVK-ELGIDGLIVT-NTTVSRPAGLQGALRS 298 Query: 247 NHGGRQLDEVSA-SIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRP- 304 GG + S +RE+ A +G++ + GGV +G D L+ + GA + L Sbjct: 299 ETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTAL 358 Query: 305 ILWGLACKGEDGVKEVLDILTAE 327 WG G+ VK L+ L E Sbjct: 359 TFWGPPVVGK--VKRELEALLKE 379 >2ISS-A nrPDB Length = 313 Score = 34.7 bits (78), Expect = 0.059, Method: Composition-based stats. Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 4/56 (7%) Query: 255 EVSASIDALREVVAAVKGKIEV--YMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 E+ A ++ LREV G++ V + GGV T D + LGA +F+G I Sbjct: 209 EIGAPVELLREV--KRLGRLPVVNFAAGGVATPADAALMMMLGADGVFVGSGIFKS 262 >4WY0-A nrPDB Length = 305 Score = 34.7 bits (78), Expect = 0.063, Method: Composition-based stats. Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 4/53 (7%) Query: 258 ASIDALREVVAAVKGKIEV--YMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 A ++ LRE+ G++ V + GGV T D + LGA +F+G I Sbjct: 201 APVEVLREI--KRLGRLPVVNFAAGGVTTPADAALMMHLGADGVFVGSGIFKS 251 >4UTT-A nrPDB Length = 229 Score = 34.3 bits (77), Expect = 0.082, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 4/82 (4%) Query: 226 ILTKEDAELAMKHNVQGI--VVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVR 283 I T E+ A K + +S + S + L E+V V KI V +G + Sbjct: 136 ISTLEEGIEAEKLGFDCVSTTLSGYTPYSKQSNSVDFELLEELVKTV--KIPVICEGRIN 193 Query: 284 TGTDVLKALALGARCIFLGRPI 305 T ++ KAL LGA +G I Sbjct: 194 TPEELKKALDLGAYSAVVGGAI 215 >1B0U-A nrPDB Length = 262 Score = 34.3 bits (77), Expect = 0.087, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 47/122 (38%), Gaps = 25/122 (20%) Query: 207 WNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQ-GIVVSNHGGRQLDEVSASIDALRE 265 W+ +++L+++ PI + G+ + E A+K+ + GI Sbjct: 105 WSHMTVLENVMEAPIQVLGLSKHDARERALKYLAKVGID--------------------- 143 Query: 266 VVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILT 325 +GK V++ GG + + +ALA+ + P L + V ++ L Sbjct: 144 --ERAQGKYPVHLSGGQQQRVSIARALAMEPDVLLFDEPT-SALDPELVGEVLRIMQQLA 200 Query: 326 AE 327 E Sbjct: 201 EE 202 >5ZKN-A nrPDB Length = 241 Score = 34.0 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 34/96 (35%), Gaps = 2/96 (2%) Query: 210 LSLLQSITRLPIILKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAA 269 ++ ++ + + I + ++A A K + + G D Sbjct: 133 IAEIKEKYPNQLFMADISSVDEALYAEKIGFDIVGTTLVGYT--DYTKNYKALEELKKVV 190 Query: 270 VKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPI 305 KI V +G + T KAL +GA + +G I Sbjct: 191 KVVKIPVIAEGNIDTPLKAKKALEIGAFAVVVGGAI 226 >2XZ9-A nrPDB Length = 324 Score = 33.6 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 21/45 (46%) Query: 260 IDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRP 304 + L+++ A +V + + T DV ALA GA + L R Sbjct: 4 LKQLKDLPAETPDGKKVMLAANIGTPKDVASALANGAEGVGLFRT 48 >2NV2-A nrPDB Length = 294 Score = 33.6 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 13/92 (14%) Query: 258 ASIDALREVVAAVKGKIEV--YMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGED 315 A + L ++ GK+ V + GGV T D + LGA +F+G I Sbjct: 191 APYELLLQIKK--DGKLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKS------- 241 Query: 316 GVKEVLDILTAELHRCMTLSGCQSVAEISPDL 347 A + + + +AE+S +L Sbjct: 242 --DNPAKFAKAIVEATTHFTDYKLIAELSKEL 271 >4XZ9-A nrPDB Length = 223 Score = 33.6 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 43/106 (40%), Gaps = 8/106 (7%) Query: 226 ILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSAS---IDALREVVAAVKGKIEVYMDGGV 282 + A LA K V VS + GR D ID +R + K ++ + + Sbjct: 112 VFNPIQALLAAKAGVT--YVSPYVGRLDDIGEDGMQIIDMIRTIFNNYIIKTQILVAS-I 168 Query: 283 RTGTDVLKALALGARCIFLGRPILWGLAC--KGEDGVKEVLDILTA 326 R VL++ +GA + + +L L K ++G+ + L+ Sbjct: 169 RNPIHVLRSAVIGADVVTVPFNVLKSLMKHPKTDEGLAKFLEDWKK 214 >1TJR-A nrPDB Length = 261 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 29/64 (45%), Gaps = 1/64 (1%) Query: 210 LSLLQSITRLPIILK-GILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVA 268 + ++ +T P+ + GI E + + G+++ + RQL E ++ LR + Sbjct: 192 IQEVKKVTNKPVAVGFGISKPEHVKQIAQWGADGVIIGSAMVRQLGEAASPKQGLRRLEE 251 Query: 269 AVKG 272 +G Sbjct: 252 YARG 255 >5CSS-A nrPDB Length = 226 Score = 33.2 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Query: 261 DALREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 + + ++V +G V + G++TG DV +++ LGAR I + ++ Sbjct: 156 EIIEDIVKIYEGTGTSVLVGAGIKTGEDVRRSIGLGARGILVASGVVKS 204 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 17/114 (14%), Positives = 39/114 (34%), Gaps = 13/114 (11%) Query: 134 DWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRALKEEKPT 193 D +++A L F +V+ ++ R+ I + + + Sbjct: 97 PRDTIINTLKKASKLDFT-IVLCVENAEEAKYFREYE-----PDFIAYEPRDLIGGDVSV 150 Query: 194 QSVPVSFPKASFCWNDLSLLQSITRLPIIL-KGILTKEDAELAMKHNVQGIVVS 246 + D+ + T +++ GI T ED ++ +GI+V+ Sbjct: 151 STAKPEII------EDIVKIYEGTGTSVLVGAGIKTGEDVRRSIGLGARGILVA 198 >2Z6J-A nrPDB Length = 332 Score = 33.2 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 26/75 (34%), Gaps = 2/75 (2%) Query: 232 AELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKA 291 A+ K ++ ++ +R+V A+ I V GG+ G Sbjct: 123 AKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATAIS--IPVIAAGGIADGEGAAAG 180 Query: 292 LALGARCIFLGRPIL 306 LGA + +G + Sbjct: 181 FMLGAEAVQVGTRFV 195 >1MJH-A nrPDB Length = 162 Score = 33.2 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 44/119 (36%), Gaps = 12/119 (10%) Query: 166 RRDKRNQ----LNLEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPI 221 R+ + + L L L K + + E + + K +L + + I Sbjct: 44 EREIKKRDIFSLLLGVAGLNKSVEEFENELKNKLTEEAKNKMENIKKELEDVGFKVK-DI 102 Query: 222 ILKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGK--IEVYM 278 I+ GI +E ++A V I++ +HG L E+ L V V K V + Sbjct: 103 IVVGIPHEEIVKIAEDEGVDIIIMGSHGKTNLKEIL-----LGSVTENVIKKSNKPVLV 156 >4N6F-A nrPDB Length = 256 Score = 33.2 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 38/90 (42%), Gaps = 6/90 (6%) Query: 219 LPIILKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYM 278 LP IL + T E A ++ + GR + +A + + ++ I V + Sbjct: 140 LPFILPDLATARALEEAGCAALRVMASPVASGRGIANPAAIRELIEQIG------IPVVV 193 Query: 279 DGGVRTGTDVLKALALGARCIFLGRPILWG 308 +GG+ + V +A+ LGA + ++ Sbjct: 194 EGGIGSARHVAEAMELGASATLVNTALVRA 223 >1WV2-A nrPDB Length = 265 Score = 33.2 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 18/38 (47%) Query: 271 KGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 + K+ V +D GV T +D A+ LG + + I Sbjct: 185 EAKVPVLVDAGVGTASDAAIAMELGCEAVLMNTAIAHA 222 >3W7D-A nrPDB Length = 313 Score = 32.4 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 27/67 (40%), Gaps = 8/67 (11%) Query: 276 VYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLS 335 V+ GGV +G D + GA + +G + ++ + L EL M Sbjct: 246 VFGCGGVYSGEDAFLHILAGASMVQVGTAL--------QEEGPGIFTRLEDELLEIMARK 297 Query: 336 GCQSVAE 342 G +++ E Sbjct: 298 GYRTLEE 304 >6B8S-A nrPDB Length = 359 Score = 32.4 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 49/330 (14%), Positives = 102/330 (30%), Gaps = 78/330 (23%) Query: 43 KRIRLRPRYLRDMSKVDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANIC 102 + + I G P+ ++ D S RA Sbjct: 49 SQWGYK--------NPKLENEILGLNFPNPLGLAA-------GFDKNASMLRALIAFGFG 93 Query: 103 YVISSYASYSLEDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVL 162 Y+ + +L + E R F ++ +Q A +GF VL Sbjct: 94 YL----EAGTLTNEAQVGNERPRLF-------RHIEEESLQNA--MGFNNY-----GAVL 135 Query: 163 GNRRRDKRNQLNLEANILLKDLRALKEEKPTQSV------------PVSFPKASFCWNDL 210 G R ++ I L + +++ + +F +S +L Sbjct: 136 GARSFNRFAPYKTPIGINLGKNKHIEQAHALEDYKAVLNQCLNIGDYYTFNLSSPNTPNL 195 Query: 211 SLLQSI-------------TRLPIILKGI--LTKED----AELAMKHNVQGIVVSN---- 247 LQ+ T P+ LK L +D A++ GI+ +N Sbjct: 196 RDLQNKAFVNELFCMAKEMTHKPLFLKIAPDLEIDDMLEIVNSAIEAGAHGIIATNTTID 255 Query: 248 ---------HGGRQLDEVSA-SIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGAR 297 GG ++ S + +E+ A K + GG+ + + + +GA Sbjct: 256 KSLVFAPKEMGGLSGKCLTKKSREVFKELAKAFFNKSVLVSVGGISDAKEAYERIKMGAS 315 Query: 298 CIFLGRPILWGLACKGEDGVKEVLDILTAE 327 + + ++ ++ +K+++ +L + Sbjct: 316 LLQIYSAFIYNGPNLCQNILKDLVKLLQKD 345 >1AK5-A nrPDB Length = 503 Score = 32.0 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 51/162 (31%), Gaps = 20/162 (12%) Query: 164 NRRRDKRNQLNLEANILLKDLRA---LKEEKPTQSVPVSFPKASFCWNDLS--LLQSIT- 217 N D + + + A I +D R E + + W ++ ++ Sbjct: 223 NELVDSQKRYLVGAGINTRDFRERVPALVEAGADVLCIDSSDGFSEWQKITIGWIREKYG 282 Query: 218 -RLPIILKGILTKEDAELAMKHNVQ----------GIVVSNHGGRQLDEVSASIDALREV 266 ++ + I+ E + G + +A ID + E Sbjct: 283 DKVKVGAGNIVDGEGFRYLADAGADFIKIGIGGGSICITREQKGIGRGQATAVIDVVAER 342 Query: 267 VAAVKGK---IEVYMDGGVRTGTDVLKALALGARCIFLGRPI 305 + I V DGG+ + ALA+GA I LGR Sbjct: 343 NKYFEETGIYIPVCSDGGIVYDYHMTLALAMGADFIMLGRYF 384 >2YZR-A nrPDB Length = 330 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 4/53 (7%) Query: 260 IDALREVVAAVK--GKIEV--YMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 ID L EV+ VK G++ V + GGV T D + LG+ +F+G I Sbjct: 225 IDGLYEVLLEVKKLGRLPVVNFAAGGVATPADAALMMQLGSDGVFVGSGIFKS 277 >5K8C-A nrPDB Length = 358 Score = 31.6 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 33/134 (24%), Positives = 53/134 (39%), Gaps = 14/134 (10%) Query: 227 LTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASI--DALREVVAAVKGKIEVYMDG-GVR 283 +A + +K I V+ +DE ++I DAL E V A GK+ V + G G Sbjct: 49 GKPLEARIPVKAQDLLIWVN------VDEEPSTIQIDALTEQVQAFNGKLPVSVVGLGGG 102 Query: 284 TGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEV----LDILTAELHRCMTLSGCQS 339 + DV KA++L G + G + V + + AE R L G Sbjct: 103 STMDVAKAVSLMLTNPG-GSAMYQGWDLIKKPAVHHIGIPTISGTGAEASRTAVLCGPVR 161 Query: 340 VAEISPDLIQFSRL 353 ++ D F ++ Sbjct: 162 KLGLNSDYTVFDQI 175 >3O07-A nrPDB Length = 291 Score = 31.6 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 4/61 (6%) Query: 250 GRQLDEVSASIDALREVVAAVKGKIEV--YMDGGVRTGTDVLKALALGARCIFLGRPILW 307 + +E+ + L++V+ KGK+ V + GGV T D + LG +F+G I Sbjct: 177 AKVAEEMRVPVSLLKDVLE--KGKLPVVNFAAGGVATPADAALLMQLGCDGVFVGSGIFK 234 Query: 308 G 308 Sbjct: 235 S 235 >3L5A-A nrPDB Length = 419 Score = 31.3 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 18/41 (43%), Gaps = 1/41 (2%) Query: 266 VVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPIL 306 V + G+I + GG+ + L AL A + + P + Sbjct: 311 VYEHLAGRIPLIASGGINSPESALDALQ-HADMVGMSSPFV 350 >1OK6-A nrPDB Length = 263 Score = 31.3 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 44/131 (33%), Gaps = 35/131 (26%) Query: 200 FPKASFCWNDLSLLQSITR------LPIILKGILTKED-------------AELAMKHNV 240 +P + F W L I R LP+++ A +A++ Sbjct: 114 YPGSGFEWKMFEELARIKRDAVKFDLPLVVWSYPRGGKVVNETAPEIVAYAARIALELGA 173 Query: 241 QGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGT--DVLK----ALAL 294 + + G + V GK+ V M GG +T T D LK L Sbjct: 174 DAMKIKYTGD------PKTF----SWAVKVAGKVPVLMSGGPKTKTEEDFLKQVEGVLEA 223 Query: 295 GARCIFLGRPI 305 GA I +GR + Sbjct: 224 GALGIAVGRNV 234 >1VHN-A nrPDB Length = 318 Score = 31.3 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 49/134 (36%), Gaps = 18/134 (13%) Query: 233 ELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKAL 292 + ++ V + + Q A AL + ++ +I ++ G + T D +AL Sbjct: 147 RILVEEGVDEVFIHTRTVVQSFTGRAEWKAL----SVLEKRIPTFVSGDIFTPEDAKRAL 202 Query: 293 -ALGARCI-----FLGRPILWG-------LACKGEDGVKEVLDILTAELHRCMTLSGCQ- 338 G + +GRP ++ E +E+L L + G + Sbjct: 203 EESGCDGLLVARGAIGRPWIFKQIKDFLRSGKYSEPSREEILRTFERHLELLIKTKGERK 262 Query: 339 SVAEISPDLIQFSR 352 +V E+ L +++ Sbjct: 263 AVVEMRKFLAGYTK 276 >1H5Y-A nrPDB Length = 253 Score = 30.9 bits (68), Expect = 0.81, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 39/97 (40%), Gaps = 24/97 (24%) Query: 220 PIILKGILT------KEDAELAM---KHNVQGIVVSNHGGRQLDEVSAS------IDALR 264 +++KG+ + E+A+ + I + LD +A ID+++ Sbjct: 18 KVVVKGVNFQGIREVGDPVEMAVRYEEEGADEIAI-------LDITAAPEGRATFIDSVK 70 Query: 265 EVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFL 301 V AV I V + GGVR+ D GA + + Sbjct: 71 RVAEAVS--IPVLVGGGVRSLEDATTLFRAGADKVSV 105 >2YZ2-A nrPDB Length = 266 Score = 30.9 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 25/57 (43%), Gaps = 1/57 (1%) Query: 269 AVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILT 325 + K ++ ++ GG + + + + L P++ GL +G+ + +++ Sbjct: 130 SFKDRVPFFLSGGEKRRVAIASVIVHEPDILILDEPLV-GLDREGKTDLLRIVEKWK 185 >4FIQ-A nrPDB Length = 335 Score = 30.9 bits (68), Expect = 0.95, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 19/39 (48%), Gaps = 2/39 (5%) Query: 272 GKIEV--YMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 G++ V + GGV T D +A+G +F+G I Sbjct: 246 GRLPVVNFAAGGVATPADAALMMAMGMDGVFVGSGIFKS 284 >1WX0-A nrPDB Length = 223 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 33/86 (38%), Gaps = 4/86 (4%) Query: 226 ILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVK-GKIEV-YMDGGVR 283 I + A LA + VS GR D + LRE+V ++ + V + +R Sbjct: 118 IFSANQALLAARAGAS--YVSPFLGRVDDISWDGGELLREIVEMIQVQDLPVKVIAASIR 175 Query: 284 TGTDVLKALALGARCIFLGRPILWGL 309 V +A LGA + + L Sbjct: 176 HPRHVTEAALLGADIATMPHAVFKQL 201 >4ADT-A nrPDB Length = 297 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 23/54 (42%), Gaps = 4/54 (7%) Query: 257 SASIDALREVVAAVKGKIEV--YMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 A ID + ++ ++ V + GG+ T D + LG +F+G I Sbjct: 193 RAPIDLI--LLTRKLKRLPVVNFAAGGIATPADAAMCMQLGMDGVFVGSGIFES 244 >2Y88-A nrPDB Length = 244 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 6/60 (10%) Query: 261 DALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPIL----WGLACKGEDG 316 + L EVV + ++V + GG+R + ALA G + +G L W GE G Sbjct: 64 ELLAEVVGKL--DVQVELSGGIRDDESLAAALATGCARVNVGTAALENPQWCARVIGEHG 121 >4EVZ-A nrPDB Length = 258 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 39/107 (36%), Gaps = 20/107 (18%) Query: 222 ILKGILT------KEDAELAM---KHNVQGI----VVSNHGGRQLDEVSASIDALREVVA 268 ++KG+ + ELA + + + ++H GR+ ++ + Sbjct: 17 VVKGVNFENLRDAGDPVELAARYDEEGADELVFLDITASHEGRE-----TMLEVVERTAE 71 Query: 269 AVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGED 315 V I + + GG+R+ D + L GA + + + E Sbjct: 72 QVF--IPLTVGGGIRSVEDASRLLRAGADKVSINTAAVKNPELITEA 116 >5LNT-A nrPDB Length = 316 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 24/55 (43%), Gaps = 4/55 (7%) Query: 256 VSASIDALREVVAAVKGKIEV--YMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 ++A D + + G++ V + GGV T D + LG +F+G + Sbjct: 206 IAAPYDLVVQTKE--LGRLPVVQFAAGGVATPADAALMMQLGCDGVFVGSGVFKS 258 >1N7K-A nrPDB Length = 234 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 15/30 (50%) Query: 276 VYMDGGVRTGTDVLKALALGARCIFLGRPI 305 V GG+R+G D + A+ GA I + Sbjct: 195 VKASGGIRSGIDAVLAVGAGADIIGTSSAV 224 >2ZBT-A nrPDB Length = 297 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 34/171 (19%), Positives = 59/171 (34%), Gaps = 48/171 (28%) Query: 187 LKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQGIVVS 246 K E T +V + A W ++ +QS+ +ED +A Sbjct: 151 TKGEAGTGNVVEAVRHARTMWKEIRYVQSL------------REDELMAYAK-------- 190 Query: 247 NHGGRQLDEVSASIDALREVVAAVKGKIEV--YMDGGVRTGTDVLKALALGARCIFLG-- 302 E+ A + L + V G++ V + GG+ T D + LG +F+G Sbjct: 191 --------EIGAPFE-LVKWVHD-HGRLPVVNFAAGGIATPADAALMMHLGMDGVFVGSG 240 Query: 303 -----------RPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAE 342 R I+ +A + EVL ++ +L M + E Sbjct: 241 IFKSGDPRKRARAIVRAVAHYNDP---EVLAEVSEDLGEPMVGINLDQLKE 288 >3GNN-A nrPDB Length = 298 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 36/79 (45%), Gaps = 13/79 (16%) Query: 225 GILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRT 284 + T + A+ H + +++ N ++D +R+ V +G+ + + GGV Sbjct: 215 EVETLDQLRTALAHGARSVLLDNF----------TLDMMRDAVRVTEGRAVLEVSGGVN- 263 Query: 285 GTDVLKALA-LGARCIFLG 302 D ++A+A G I +G Sbjct: 264 -FDTVRAIAETGVDRISIG 281 >4AXK-A nrPDB Length = 250 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 24/47 (51%), Gaps = 2/47 (4%) Query: 261 DALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILW 307 + + E+ + K+E + GG+R + +ALA GA + +G L Sbjct: 64 ELMAEITRQLDIKVE--LTGGIRDDASLERALATGATRVNIGTAALE 108 >1KA9-F nrPDB Length = 252 Score = 29.3 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 32/89 (35%), Gaps = 12/89 (13%) Query: 222 ILKGILT--------KEDAELAMKH-NVQGIVVSNHGGRQLDEVSASIDALREVVAAVKG 272 ++KG+ +A A +V + + +D + V V Sbjct: 18 VVKGVNFVNLRDAGDPVEAARAYDEAGADELVFLDISATHEERAI-LLDVVARVAERVF- 75 Query: 273 KIEVYMDGGVRTGTDVLKALALGARCIFL 301 I + + GGVR+ D K L GA + + Sbjct: 76 -IPLTVGGGVRSLEDARKLLLSGADKVSV 103 >5LNS-A nrPDB Length = 316 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 22/53 (41%), Gaps = 4/53 (7%) Query: 258 ASIDALREVVAAVKGKIEV--YMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 A D + + G++ V + GGV T D + LG +F+G I Sbjct: 207 APYDLVMQTKQ--LGRLPVVQFAAGGVATPADAALMMQLGCDGVFVGSGIFKS 257 >1UB3-A nrPDB Length = 220 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 44/115 (38%), Gaps = 11/115 (9%) Query: 208 NDLSLLQSITRLPIILK-GILTKED----AELAMKHNVQGIVVS-NHGGRQLDEVSASID 261 + L +IL+ G + E+ AE A++ + S G R AS++ Sbjct: 110 RAVREAVPQAVLKVILETGYFSPEEIARLAEAAIRGGADFLKTSTGFGPRG-----ASLE 164 Query: 262 ALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDG 316 + +V +G+ +V GG+R L+ L GA + + G G Sbjct: 165 DVALLVRVAQGRAQVKAAGGIRDRETALRMLKAGASRLGTSSGVALVAGEGGTLG 219 >1O4U-A nrPDB Length = 285 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 9/76 (11%), Positives = 27/76 (35%), Gaps = 8/76 (10%) Query: 208 NDLSLLQSITRLPIILK-GILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREV 266 + ++ I ++ + EDA A++ +++ N + + Sbjct: 181 RAVQEVRKIIPFTTKIEVEVENLEDALRAVEAGADIVMLDN-------LSPEEVKDISRR 233 Query: 267 VAAVKGKIEVYMDGGV 282 + + + V + GG+ Sbjct: 234 IKDINPNVIVEVSGGI 249 >4Z7R-A nrPDB Length = 299 Score = 28.9 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 20/43 (46%) Query: 249 GGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKA 291 GG++L + ++ A + G + DG V D+++A Sbjct: 186 GGKRLAYIPGCARVTEDLKARIAGADALLFDGTVLEDDDMIRA 228 >5UE9-A nrPDB Length = 306 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 257 SASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLG 302 ++ + +V V I + GGV + DVL+ GA + +G Sbjct: 223 PVALKLIHQVAQVV--DIPIIGMGGVESAQDVLEMYMAGASAVAVG 266 >2X0S-A nrPDB Length = 913 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 13/28 (46%), Gaps = 4/28 (14%) Query: 281 GVRT----GTDVLKALALGARCIFLGRP 304 GVRT D KA + GA + L R Sbjct: 561 GVRTNADTPADAAKARSFGAEGVGLCRT 588 >4MM1-A nrPDB Length = 250 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 36/76 (47%), Gaps = 7/76 (9%) Query: 253 LDEVSASIDALRE----VVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 L+ S + + + E +V +I + + GG+R+G D + GA + G + Sbjct: 173 LEAGSGAPEHVPEEMIALVKRCTDQI-LIVGGGIRSGEDAARVAGAGADVVVTG--TVVE 229 Query: 309 LACKGEDGVKEVLDIL 324 + ED ++E+++ + Sbjct: 230 NSDNVEDKIREIVEGM 245 >1W0M-A nrPDB Length = 226 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 25/154 (16%), Positives = 52/154 (33%), Gaps = 15/154 (9%) Query: 96 AQEANICYVISSYASYSLEDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVI 155 AQ A++ + A SLE+I A G + ++V +A++LG +V Sbjct: 61 AQGADVEAGGAHTAHVSLENIKEAGGSGVILNHSEAPLKLNDLARLVAKAKSLGLDVVVC 120 Query: 156 TIDTPVLGNRRRDKRNQLNLEANILLKDL-RALKEEKPTQSVPVSFPKAS--FCWNDLSL 212 D R L + + + + + + Sbjct: 121 APD-------PRTSLAAAALGPHAVAVEPPELIGTGRAVSRYKPEAIVETVGLVSRHFPE 173 Query: 213 LQSITRLPIILKGILTKEDAELAMKHNVQGIVVS 246 + IT GI + +D A++ +G++++ Sbjct: 174 VSVITG-----AGIESGDDVAAALRLGTRGVLLA 202 >3BW4-A nrPDB Length = 369 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 29/90 (32%), Gaps = 13/90 (14%) Query: 228 TKEDAELAMKHNVQ-----GIVVSNHGGRQLDEVS------ASIDALREVVAAVKGKIEV 276 T E+A G+ H G D + L +V AV I V Sbjct: 154 TPEEARAVEAAGADAVIAQGVEAGGHQGTHRDSSEDDGAGIGLLSLLAQVREAV--DIPV 211 Query: 277 YMDGGVRTGTDVLKALALGARCIFLGRPIL 306 GG+ G + LA GA LG L Sbjct: 212 VAAGGIMRGGQIAAVLAAGADAAQLGTAFL 241 >6OD1-A nrPDB Length = 337 Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 15/39 (38%) Query: 263 LREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFL 301 L E + + V + D+ KAL LG + L Sbjct: 69 LLEHIRNRGDQTPVLVISATENMADIAKALRLGVEDVLL 107 >4RY2-A nrPDB Length = 730 Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 32/92 (34%), Gaps = 1/92 (1%) Query: 255 EVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPI-LWGLACKG 313 E S A + + + KIE M + G + +L LG + LW A Sbjct: 359 ETIKSFGAEEQTEKSTRDKIETVMKSSFKEGMLYINLSSLTGIVAGLGGIVILWAGAYNV 418 Query: 314 EDGVKEVLDILTAELHRCMTLSGCQSVAEISP 345 G +L L+ +++ ++ P Sbjct: 419 IKGNMSGGQLLAFNALLAYFLTPVKNLIDLQP 450 >3EOD-A nrPDB Length = 130 Score = 28.6 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 15/39 (38%) Query: 263 LREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFL 301 L E + + V + D+ KAL LG + L Sbjct: 69 LLEHIRNRGDQTPVLVISATENMADIAKALRLGVEDVLL 107 >3IJQ-A nrPDB Length = 338 Score = 28.6 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 24/147 (16%), Positives = 56/147 (38%), Gaps = 17/147 (11%) Query: 100 NICYVISSYASYSLEDIVAAAPEGFRWFQ-LYMKSDWDFNKQMVQRAEALGFKALVITID 158 + + + + A E F L +K D +K+M++ + L I +D Sbjct: 122 KTPSTTFTIGIDTPDVVRAKTKECAGLFNILKVKLGRDNDKEMIETIRS--VTDLPIAVD 179 Query: 159 TPVLGNRRRDKRNQLNLEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITR 218 G + D++ L++ + K + +++ P + + +D++ + + Sbjct: 180 -ANQGWK--DRQYALDMIHWLKEKGIVMIEQPMPKEQL-----------DDIAWVTQQSP 225 Query: 219 LPIILKGILTKEDAELAMKHNVQGIVV 245 LP+ L + A+K GI + Sbjct: 226 LPVFADESLQRLGDVAALKGAFTGINI 252 >4WQ4-C nrPDB Length = 237 Score = 28.6 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 281 GVRTGTDVLKALALGARCIFLGRPILWGLACKGE--DGVKEVLDILTAEL 328 GVR G + + LALGA +G L +A +G VL + A + Sbjct: 70 GVRIGIGIAQGLALGAELPMIGVSTLMTMAQGAWRKNGATRVLAAIDARM 119 >5G1T-A nrPDB Length = 256 Score = 28.6 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 16/35 (45%) Query: 274 IEVYMDGGVRTGTDVLKALALGARCIFLGRPILWG 308 + V + GGVRT DV L G + +G + Sbjct: 77 VPVQVGGGVRTEEDVAALLKAGVARVVIGSTAVKS 111 >4IQL-A nrPDB Length = 333 Score = 28.2 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 4/56 (7%) Query: 232 AELAMKHNVQGIVVSNH--GGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTG 285 A + V IV GG E + ++ + EVV AV I V GG+ +G Sbjct: 142 ARKSEAAGVDAIVAEGFEAGGHNGREETTTLCLIPEVVDAVN--IPVVAAGGIASG 195 >3N2C-A nrPDB Length = 423 Score = 28.2 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 19/38 (50%) Query: 250 GRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTD 287 R +D V A+RE + +I++ GGV + TD Sbjct: 165 ARVVDGVEGVRLAVREEIQKGATQIKIMASGGVASPTD 202 >2NU8-B nrPDB Length = 388 Score = 28.2 bits (61), Expect = 6.5, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 282 VRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLD 322 V TD+ K L LGA R +++ + +G +++V + Sbjct: 98 VEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAE 138 >2ONK-A nrPDB Length = 240 Score = 27.8 bits (60), Expect = 7.1, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 267 VAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTA 326 +A + + + GG R + +AL + R + L P L + K + + E L + Sbjct: 116 IAHLLDRKPARLSGGERQRVALARALVIQPRLLLLDEP-LSAVDLKTKGVLMEELRFVQR 174 Query: 327 ELH 329 E Sbjct: 175 EFD 177 >3NG3-A nrPDB Length = 227 Score = 27.8 bits (60), Expect = 8.3, Method: Composition-based stats. Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 2/54 (3%) Query: 258 ASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLG--RPILWGL 309 AS+ A+ + AV G++ V GG+RT D L L GA + L R +L GL Sbjct: 173 ASVRAVALMAEAVGGRLGVKASGGIRTAADALAMLDAGATRLGLSGTRAVLDGL 226 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.127 0.310 Lambda K H 0.267 0.0394 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,298,051 Number of Sequences: 36641 Number of extensions: 404782 Number of successful extensions: 1594 Number of sequences better than 10.0: 120 Number of HSP's better than 10.0 without gapping: 124 Number of HSP's successfully gapped in prelim test: 61 Number of HSP's that attempted gapping in prelim test: 1380 Number of HSP's gapped (non-prelim): 205 length of query: 353 length of database: 10,336,785 effective HSP length: 98 effective length of query: 255 effective length of database: 6,745,967 effective search space: 1720221585 effective search space used: 1720221585 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.4 bits)