BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q07478 (446 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5SUQ-A nrPDB 921 0.0 5SUP-A nrPDB 798 0.0 1XTI-A nrPDB 557 e-159 1T6N-A nrPDB 345 3e-95 2HYI-C nrPDB 252 3e-67 5ANR-B nrPDB 249 2e-66 4BRW-A nrPDB 243 2e-64 3EIQ-A nrPDB 224 7e-59 5IVL-B nrPDB 220 1e-57 2VSX-A nrPDB 213 1e-55 6B4I-E nrPDB 194 7e-50 1HV8-A nrPDB 192 2e-49 3PEW-A nrPDB 188 3e-48 4NHO-A nrPDB 186 1e-47 4D25-A nrPDB 186 2e-47 3JCR-F nrPDB 183 1e-46 2DB3-A nrPDB 179 2e-45 4KBG-A nrPDB 176 2e-44 3FHO-A nrPDB 176 2e-44 2Z0M-A nrPDB 173 1e-43 6CZ5-A nrPDB 164 5e-41 2I4I-A nrPDB 163 1e-40 5DTU-A nrPDB 158 4e-39 6CB1-p nrPDB 151 4e-37 5GJU-A nrPDB 139 2e-33 3BOR-A nrPDB 138 6e-33 5ZWN-y nrPDB 137 9e-33 4W7S-A nrPDB 137 1e-32 1VEC-A nrPDB 133 2e-31 5ZBZ-A nrPDB 131 5e-31 1Q0U-A nrPDB 129 4e-30 4LJY-A nrPDB 128 4e-30 2GXQ-A nrPDB 126 2e-29 1QVA-A nrPDB 124 6e-29 3BER-A nrPDB 119 4e-27 2OXC-A nrPDB 117 9e-27 3SQW-A nrPDB 112 4e-25 3I62-A nrPDB 112 4e-25 6AIC-A nrPDB 102 4e-22 2KBE-A nrPDB 100 1e-21 3FMO-B nrPDB 97 2e-20 1WRB-A nrPDB 96 2e-20 3FHC-B nrPDB 96 3e-20 4PX9-A nrPDB 96 4e-20 2PL3-A nrPDB 95 6e-20 5H1Y-A nrPDB 92 6e-19 3IUY-A nrPDB 91 8e-19 5GVS-A nrPDB 89 4e-18 3DKP-A nrPDB 86 4e-17 3FE2-A nrPDB 79 5e-15 3LY5-A nrPDB 76 2e-14 4Q48-A nrPDB 54 1e-07 5V9X-A nrPDB 52 5e-07 6CRM-A nrPDB 50 2e-06 5TNU-A nrPDB 49 6e-06 2FWR-A nrPDB 46 3e-05 1OYY-A nrPDB 46 3e-05 5LST-A nrPDB 44 1e-04 2WWY-A nrPDB 44 1e-04 5LB8-A nrPDB 42 5e-04 5LBA-B nrPDB 42 5e-04 4CDG-A nrPDB 40 0.003 1GM5-A nrPDB 37 0.018 2FUG-6 nrPDB 37 0.024 5X0Y-O nrPDB 33 0.20 6G19-A nrPDB 33 0.29 6H8K-K nrPDB 33 0.35 4A2Q-A nrPDB 33 0.36 4A36-A nrPDB 33 0.36 4A2W-A nrPDB 32 0.39 1WP9-A nrPDB 32 0.52 5UMD-O nrPDB 31 0.98 4WZ7-K nrPDB 31 1.0 4GL2-A nrPDB 31 1.1 6GCS-K nrPDB 31 1.2 6F4A-B nrPDB 31 1.2 5JBJ-A nrPDB 30 1.6 2NMV-A nrPDB 30 2.0 6G72-B nrPDB 30 2.1 5GPN-a nrPDB 30 2.1 5O31-B nrPDB 30 2.5 4BPB-A nrPDB 30 2.6 5XTD-C nrPDB 30 2.6 5HZR-A nrPDB 30 2.7 3DIN-A nrPDB 30 3.0 4ON9-A nrPDB 29 3.2 2XYJ-A nrPDB 28 5.9 5JCF-A nrPDB 28 6.2 1D9Z-A nrPDB 28 7.5 3G25-A nrPDB 28 9.9 >5SUQ-A nrPDB Length = 446 Score = 921 bits (2380), Expect = 0.0, Method: Compositional matrix adjust. Identities = 446/446 (100%), Positives = 446/446 (100%) Query: 1 MSHEGEEDLLEYSDNEQEIQIDASKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIH 60 MSHEGEEDLLEYSDNEQEIQIDASKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIH Sbjct: 1 MSHEGEEDLLEYSDNEQEIQIDASKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIH 60 Query: 61 STGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLST 120 STGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLST Sbjct: 61 STGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLST 120 Query: 121 LQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKN 180 LQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKN Sbjct: 121 LQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKN 180 Query: 181 KDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRD 240 KDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRD Sbjct: 181 KDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRD 240 Query: 241 KQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQL 300 KQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQL Sbjct: 241 KQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQL 300 Query: 301 LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRIC 360 LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRIC Sbjct: 301 LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRIC 360 Query: 361 VSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLA 420 VSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLA Sbjct: 361 VSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLA 420 Query: 421 KIQERFDVKIAEFPEEGIDPSTYLNN 446 KIQERFDVKIAEFPEEGIDPSTYLNN Sbjct: 421 KIQERFDVKIAEFPEEGIDPSTYLNN 446 >5SUP-A nrPDB Length = 390 Score = 798 bits (2061), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/389 (99%), Positives = 387/389 (99%) Query: 58 GIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFV 117 + STGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFV Sbjct: 2 AMGSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFV 61 Query: 118 LSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL 177 LSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL Sbjct: 62 LSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL 121 Query: 178 LKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRAT 237 LKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRAT Sbjct: 122 LKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRAT 181 Query: 238 PRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKL 297 PRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKL Sbjct: 182 PRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKL 241 Query: 298 AQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK 357 AQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK Sbjct: 242 AQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK 301 Query: 358 RICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEE 417 RICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEE Sbjct: 302 RICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEE 361 Query: 418 VLAKIQERFDVKIAEFPEEGIDPSTYLNN 446 VLAKIQERFDVKIAEFPEEGIDPSTYLNN Sbjct: 362 VLAKIQERFDVKIAEFPEEGIDPSTYLNN 390 >1XTI-A nrPDB Length = 391 Score = 557 bits (1436), Expect = e-159, Method: Compositional matrix adjust. Identities = 259/387 (66%), Positives = 322/387 (83%), Gaps = 3/387 (0%) Query: 58 GIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFV 117 G S+GF+DFLLKPEL RAI+DCGFEHPSEVQ IPQ+I G DVLCQAKSG+GKTAVFV Sbjct: 4 GHMSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFV 63 Query: 118 LSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL 177 L+TLQQL+PV G+V+V+V+C+ RELA+QI EY RFSKYMP+VK AVF+GG I KD E+ Sbjct: 64 LATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEV 123 Query: 178 LKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRAT 237 LK PHIVV TPGR+ AL R K ++L H+K+F++DECDK+LE+LDMRRDVQEIFR T Sbjct: 124 LKK--NCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMT 181 Query: 238 PRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKL 297 P +KQVMMFSATLS+EIRP+CR+F+Q+P+EIFVDDE KLTLHGLQQYY+KL++ EKNRKL Sbjct: 182 PHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKL 241 Query: 298 AQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK 357 LLD LEFNQV+IFVKS R L +LL NFPAI +H M QEER++RY+ FKDF++ Sbjct: 242 FDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQR 301 Query: 358 RICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEE 417 RI V+T++FGRG+DIER+N+A NYD+ ++D YLHRV RAGRFGTKGLAI+FVS + D + Sbjct: 302 RILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAK 361 Query: 418 VLAKIQERFDVKIAEFPEEGIDPSTYL 444 +L +Q+RF+V I+E P+E ID S+Y+ Sbjct: 362 ILNDVQDRFEVNISELPDE-IDISSYI 387 >1T6N-A nrPDB Length = 220 Score = 345 bits (884), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 157/222 (70%), Positives = 189/222 (85%), Gaps = 2/222 (0%) Query: 49 AGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKS 108 D KGSYV IHS+GF+DFLLKPEL RAI+DCGFEHPSEVQ IPQ+I G DVLCQAKS Sbjct: 1 GSDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKS 60 Query: 109 GLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGG 168 G+GKTAVFVL+TLQQL+PV G+V+V+V+C+ RELA+QI EY RFSKYMP+VK AVF+GG Sbjct: 61 GMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGG 120 Query: 169 TPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRR 228 I KD E+LK PHIVV TPGR+ AL R K ++L H+K+F++DECDK+LE+LDMRR Sbjct: 121 LSIKKDEEVLKK--NCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRR 178 Query: 229 DVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFV 270 DVQEIFR TP +KQVMMFSATLS+EIRP+CR+F+Q+P+EIFV Sbjct: 179 DVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFV 220 >2HYI-C nrPDB Length = 413 Score = 252 bits (643), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 136/372 (36%), Positives = 218/372 (58%), Gaps = 8/372 (2%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F L+ +L R I GFE PS +QQ I Q I G DV+ Q++SG GKTA F +S LQ Sbjct: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 LD E +++ RELA QI+ L YM +V+ GGT + +D ++ D Sbjct: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGED---IRKLDY 155 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 H+V TPGR+ ++R + + +K V+DE D++L + + + +++R P QV Sbjct: 156 GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQV 214 Query: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEERE-KNRKLAQLLD 302 ++ SATL EI + +F+ +P+ I V + +LTL G++Q+++ +E E K L L D Sbjct: 215 VLISATLPHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYD 273 Query: 303 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 362 L Q +IF + + + LT+ + +NF ++HG M Q+ER + K F+ R+ +S Sbjct: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIS 333 Query: 363 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 422 TDV+ RG+D+ +++L INYDL N + Y+HR+GR+GR+G KG+AI+FV + +D +L I Sbjct: 334 TDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKN-DDIRILRDI 392 Query: 423 QERFDVKIAEFP 434 ++ + +I E P Sbjct: 393 EQYYSTQIDEMP 404 >5ANR-B nrPDB Length = 378 Score = 249 bits (635), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 140/383 (36%), Positives = 221/383 (57%), Gaps = 14/383 (3%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F+D+ LK EL I + G+E PS +Q+ +IP ++ G D+L +AK+G GK+ +++ L++ Sbjct: 7 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 66 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 LD + +VI RELA Q+ ++ SK+M K GGT + D +++ DT Sbjct: 67 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDD--IMRLDDT 124 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 H+V+ATPGR+ L+++ + HV+ V+DE DK+L + D + +++I P+++Q+ Sbjct: 125 V-HVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMEDIILTLPKNRQI 182 Query: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDD 303 +++SAT ++ LQ P EI + +E LTL G+ QYY + ER+K L L Sbjct: 183 LLYSATFPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYAYVTERQKVHCLNTLFSR 240 Query: 304 LEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRIC--- 360 L+ NQ IIF S+ R L K ++ + +H M+QE R + F DF +C Sbjct: 241 LQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHR---NRVFHDFRNGLCRNL 297 Query: 361 VSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLA 420 V TD+F RGIDI+ +N+ IN+D A+ YLHR+GR+GRFG GLAI+ ++ +D L Sbjct: 298 VCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITY-DDRFNLK 356 Query: 421 KIQERFDVKIAEFPEEGIDPSTY 443 I+E+ +I P ID S Y Sbjct: 357 SIEEQLGTEIKPIP-SNIDKSLY 378 >4BRW-A nrPDB Length = 377 Score = 243 bits (619), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 145/381 (38%), Positives = 209/381 (54%), Gaps = 9/381 (2%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F+DF LK EL I + GFE PS +Q+ IP +I G D+L +AK+G GKTA FV+ TL++ Sbjct: 3 FEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTLEK 62 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 + P ++ +++ RELA Q K+ + V GGT + D +L+ +T Sbjct: 63 VKPKLNKIQALIMVPTRELALQTSQVVRTLGKHC-GISCMVTTGGTNLRDD--ILRLNET 119 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 HI+V TPGR+ L K DLS F++DE DK+L D + +++I P Q Sbjct: 120 V-HILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSR-DFKTIIEQILSFLPPTHQS 177 Query: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDD 303 ++FSAT + + L P EI + +E LTL G+ QYY +EER+K L L Sbjct: 178 LLFSATFPLTVDEFMDKHLHKPYEINLMEE--LTLKGITQYYAFVEERQKLHCLNTLFSK 235 Query: 304 LEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVST 363 L+ NQ IIF ST R L K + + H MKQ+ER + F+ + R V + Sbjct: 236 LQINQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRTLVCS 295 Query: 364 DVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQ 423 D+ RGIDI+ +N+ IN+D A+ YLHR+GR+GRFG GLAI+ ++ D L KI+ Sbjct: 296 DLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINW-NDRFNLYKIE 354 Query: 424 ERFDVKIAEFPEEGIDPSTYL 444 + +IA P ID S Y+ Sbjct: 355 QELGTEIAAIPAT-IDKSLYV 374 >3EIQ-A nrPDB Length = 414 Score = 224 bits (570), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 137/373 (36%), Positives = 217/373 (58%), Gaps = 7/373 (1%) Query: 63 GFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQ 122 F D L L R I GFE PS +QQ I I G DV+ QA+SG GKTA F +S LQ Sbjct: 41 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 100 Query: 123 QLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKD 182 Q++ +V+ RELA QI+ + YM A GGT + AE+ K + Sbjct: 101 QIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACI-GGTNVR--AEVQKLQM 157 Query: 183 TAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQ 242 APHI+V TPGR+ ++ +Y+ ++K FV+DE D++L + + +IF+ + Q Sbjct: 158 EAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQ 216 Query: 243 VMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEERE-KNRKLAQLL 301 V++ SAT+ ++ + ++F+++P+ I V E +LTL G++Q+YI +E E K L L Sbjct: 217 VVLLSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVEREEWKLDTLCDLY 275 Query: 302 DDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICV 361 + L Q +IF+ + + + LT+ ++A +F +HG M Q+ER + F+ R+ + Sbjct: 276 ETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLI 335 Query: 362 STDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAK 421 +TD+ RGID+++++L INYDL + Y+HR+GR GRFG KG+AI+ V ++ED+ L Sbjct: 336 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV-TEEDKRTLRD 394 Query: 422 IQERFDVKIAEFP 434 I+ ++ I E P Sbjct: 395 IETFYNTSIEEMP 407 >5IVL-B nrPDB Length = 429 Score = 220 bits (560), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 119/353 (33%), Positives = 197/353 (55%), Gaps = 6/353 (1%) Query: 62 TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 T F++ L E+ +AI GFE + +Q TIP S+ DV+ QA++G GKTA F + + Sbjct: 2 TTFQELGLSQEVMKAIERMGFEETTPIQAKTIPLSLQNKDVIGQAQTGTGKTAAFGIPIV 61 Query: 122 QQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNK 181 +++D G + +V+ RELA Q+ E + + V+ YGG I + LK Sbjct: 62 EKVDVKNGAIQALVVAPTRELAIQVSEELYKIGA-VKRVRVLPIYGGQDIERQIRALKKH 120 Query: 182 DTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDK 241 PH++V TPGR+ + + L HV V+DE D++L + D++ I P ++ Sbjct: 121 ---PHVIVGTPGRIIDHINRGTLRLEHVHTVVLDEADEMLN-MGFIEDIEAILSHVPAER 176 Query: 242 QVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLL 301 Q ++FSAT+ IR I RF+ P E+ ++T+ +QQYY+++ E++K L +LL Sbjct: 177 QTLLFSATMPDPIRRIAERFMNEP-ELVKVKAKEMTVPNIQQYYLEVHEKKKFDILTRLL 235 Query: 302 DDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICV 361 D I+F ++ R +EL + LN + A +HG + Q +R++ + FK+ I V Sbjct: 236 DIQAPELAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLSQAKRLSVLRKFKEGAIEILV 295 Query: 362 STDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKE 414 +TDV RG+DI + N+D+ + + Y+HR+GR GR G G+A++FV+ +E Sbjct: 296 ATDVAARGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGKTGVAMTFVTPRE 348 >2VSX-A nrPDB Length = 395 Score = 213 bits (542), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 136/383 (35%), Positives = 214/383 (55%), Gaps = 12/383 (3%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F D L L R + GFE PS +QQ I I G DVL QA+SG GKT F ++ LQ+ Sbjct: 24 FDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQR 83 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 +D +++ RELA QI+ + + +M D+K GGT +DAE L++ Sbjct: 84 IDTSVKAPQALMLAPTRELALQIQKVVMALAFHM-DIKVHACIGGTSFVEDAEGLRD--- 139 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 IVV TPGR+ ++ + +K F++DE D++L + + +IF P QV Sbjct: 140 -AQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSS-GFKEQIYQIFTLLPPTTQV 197 Query: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEERE-KNRKLAQLLD 302 ++ SAT+ ++ + +F++NP+ I V + +LTL G++Q+Y+ +EE E K L L D Sbjct: 198 VLLSATMPNDVLEVTTKFMRNPVRILVKKD-ELTLEGIKQFYVNVEEEEYKYECLTDLYD 256 Query: 303 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 362 + Q +IF + + ELT L F ++ + Q+ER K F+ RI +S Sbjct: 257 SISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILIS 316 Query: 363 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 422 TD+ RGID+++++L INYDL + Y+HR+GR GRFG KG+AI+FV++ ED + ++ Sbjct: 317 TDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTN-EDVGAMREL 375 Query: 423 QERFDVKIAEFPEEGIDPSTYLN 445 ++ + +I E P D +T LN Sbjct: 376 EKFYSTQIEELPS---DIATLLN 395 >6B4I-E nrPDB Length = 430 Score = 194 bits (493), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 123/408 (30%), Positives = 209/408 (51%), Gaps = 17/408 (4%) Query: 42 DNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIH--G 99 DN N + + F++ LKP+L + + GF PS++Q++ +P + Sbjct: 23 DNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPP 82 Query: 100 TDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPD 159 +++ Q++SG GKTA FVL+ L Q++P + + ELA Q + K+ P+ Sbjct: 83 QNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPE 142 Query: 160 VKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGR-LKALVREKYIDLSHVKNFVIDECD 218 +K A G +L + + + IV+ TPG L + K+ID +K FV+DE D Sbjct: 143 LKLAYAVRGN------KLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 196 Query: 219 KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTL 278 ++ + I R PR+ Q+++FSAT + ++ + +P I + E + TL Sbjct: 197 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE-TL 255 Query: 279 HGLQQYYIKLEER-EKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVH 337 ++QYY+ R EK + L L + Q +IF + A+ L L+ + Sbjct: 256 DTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLS 315 Query: 338 GHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEAD------QYL 391 G M E+R A + F++ ++++ V+T+V RGID+E++++ IN+DL + D YL Sbjct: 316 GEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYL 375 Query: 392 HRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPEEGID 439 HR+GR GRFG +GLA++ V SK +L +IQE F+ KI + +D Sbjct: 376 HRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLD 423 >1HV8-A nrPDB Length = 367 Score = 192 bits (489), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 120/376 (31%), Positives = 211/376 (56%), Gaps = 15/376 (3%) Query: 59 IHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGT-DVLCQAKSGLGKTAVFV 117 + F + L + AI + GFE P+++Q IP ++ +++ QA++G GKTA F Sbjct: 3 VEYMNFNELNLSDNILNAIRNKGFEKPTDIQMKVIPLFLNDEYNIVAQARTGSGKTASFA 62 Query: 118 LSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL 177 + ++ ++ G + +++ RELA Q+ +E + K ++K A YGG I + Sbjct: 63 IPLIELVNENNG-IEAIILTPTRELAIQVADE-IESLKGNKNLKIAKIYGGKAIYPQIKA 120 Query: 178 LKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRAT 237 LKN +IVV TPGR+ + ++L +VK F++DE D++L + +DV++I A Sbjct: 121 LKN----ANIVVGTPGRILDHINRGTLNLKNVKYFILDEADEMLN-MGFIKDVEKILNAC 175 Query: 238 PRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKL 297 +DK++++FSAT+ +EI + ++++ + I +AK+ + ++Q Y+++ E E+ L Sbjct: 176 NKDKRILLFSATMPREILNLAKKYMGDYSFI----KAKINAN-IEQSYVEVNENERFEAL 230 Query: 298 AQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK 357 +LL + EF ++F K+ EL +L F A +HG + Q +R + FK + Sbjct: 231 CRLLKNKEFYG-LVFCKTKRDTKELASMLRDIGFKAGAIHGDLSQSQREKVIRLFKQKKI 289 Query: 358 RICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEE 417 RI ++TDV RGID+ +N INY L + Y+HR+GR GR G KG AIS ++ +E ++ Sbjct: 290 RILIATDVMSRGIDVNDLNCVINYHLPQNPESYMHRIGRTGRAGKKGKAISIINRREYKK 349 Query: 418 VLAKIQERFDVKIAEF 433 L I+ +KI + Sbjct: 350 -LRYIERAMKLKIKKL 364 >3PEW-A nrPDB Length = 395 Score = 188 bits (478), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 119/397 (29%), Positives = 206/397 (51%), Gaps = 29/397 (7%) Query: 58 GIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGT--DVLCQAKSGLGKTAV 115 G + F + L PEL + I F+ PS++Q+ +P +H +++ Q++SG GKTA Sbjct: 1 GAMAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAA 60 Query: 116 FVLSTLQQLDPVPGEVAVVVICNARELAYQ---IRNEYLRFSKYMPDVKTAVFYGGTPIS 172 F L+ L +++P + + +RELA Q + E +F+K + I Sbjct: 61 FSLTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQL----------IV 110 Query: 173 KDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQE 232 D+ KNK ++V TPG + L+R K + L +K FV+DE D +L++ + Sbjct: 111 PDS-FEKNKQINAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIR 169 Query: 233 IFRATPRDKQVMMFSATLSQEIRPICRRFL--QNPLEIFVDDEAKLTLHGLQQYYIKLE- 289 + R P+D Q+++FSAT + +R ++ + N LE+ ++ + + ++Q Y+ + Sbjct: 170 VKRFLPKDTQLVLFSATFADAVRQYAKKIVPNANTLELQTNE---VNVDAIKQLYMDCKN 226 Query: 290 EREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARY 349 E +K L +L + IIFV + AN L L + +HG ++ +ER Sbjct: 227 EADKFDVLTELYGVMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLI 286 Query: 350 KAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEAD------QYLHRVGRAGRFGTK 403 F++ ++ ++T+V RGIDI +++ +NYDL A+ Y+HR+GR GRFG K Sbjct: 287 DDFREGRSKVLITTNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRK 346 Query: 404 GLAISFVSSKEDEEVLAKIQERF-DVKIAEFPEEGID 439 G+AISFV K +L+ IQ+ F D+++ P + D Sbjct: 347 GVAISFVHDKNSFNILSAIQKYFGDIEMTRVPTDDWD 383 >4NHO-A nrPDB Length = 488 Score = 186 bits (473), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 121/408 (29%), Positives = 205/408 (50%), Gaps = 44/408 (10%) Query: 53 KGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGK 112 KG + +KD L P + I CG++ P+ +Q+ IP + D++ A++G GK Sbjct: 50 KGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGK 109 Query: 113 TAVFVLSTLQQLDPVP----------GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKT 162 TA F++ L + +P G A++ + RELA QI E ++F K + ++T Sbjct: 110 TAAFLIPLLVWITTLPKIDRIEESDQGPYAII-LAPTRELAQQIEEETIKFGKPL-GIRT 167 Query: 163 AVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLE 222 GG IS++ + + + IV+ATPGRL ++ +Y+ LS V+DE D++++ Sbjct: 168 VAVIGG--ISREDQGFRLR-MGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMID 224 Query: 223 ELDMRRDVQEIFRATP--------------------------RDKQVMMFSATLSQEIRP 256 + DVQ+I P + +Q +MF+AT+ + Sbjct: 225 -MGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVER 283 Query: 257 ICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKST 316 + R +L+ P +++ K Q+ ++ + E EK +KL +L+ +IIFV Sbjct: 284 LARSYLRRPAVVYIGSAGKPHERVEQKVFL-MSESEKRKKLLAILEQGFDPPIIIFVNQK 342 Query: 317 TRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERIN 376 + L K L + A T+HG QE+R K K I V+TDV GRGIDI+ ++ Sbjct: 343 KGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVS 402 Query: 377 LAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQE 424 + +NYD+ + Y+HR+GR GR G G+AI+F+ +KED V ++++ Sbjct: 403 MVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFL-TKEDSAVFYELKQ 449 >4D25-A nrPDB Length = 434 Score = 186 bits (472), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 115/372 (30%), Positives = 198/372 (53%), Gaps = 20/372 (5%) Query: 77 IIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVA---- 132 ++ G+ P+ +Q++ IP + G D++ A++G GKTA F++ + L P ++ Sbjct: 65 VLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTGSGKTAAFLVPIINMLLQDPKDLISENG 124 Query: 133 -----VVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHI 187 V+++ REL QI NE +FS Y +K AV YGGT + + N HI Sbjct: 125 CAQPQVIIVSPTRELTLQIFNEARKFS-YGSVLKVAVAYGGTAVRHQGD---NIARGCHI 180 Query: 188 VVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRAT---PRDKQVM 244 +VATPGRL V + V+ V+D+ D +L+ M + + T +Q + Sbjct: 181 LVATPGRLHDFVERNRVSFGSVRFVVLDQADCMLDMGFMPSIEKMMLHPTMVETTKRQTL 240 Query: 245 MFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDL 304 MFSAT ++I+ + RFL N L + V + ++Q +I++ + EK L QL+++ Sbjct: 241 MFSATFPEDIQHLAGRFLNNYLFVAVGIVGGASTD-VEQIFIEVTKYEKRNSLKQLIEEN 299 Query: 305 EFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTD 364 + ++++FV++ A+ + +L+ ++HG Q ER + FK + I V+T Sbjct: 300 DGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEALQNFKSGKHCILVATA 359 Query: 365 VFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEV---LAK 421 V RG+DI+ +++ +NYDL D+Y+HR+GR GR G +G A+SF S +D + L+K Sbjct: 360 VAARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRVGNRGKAVSFYDSDQDLALVADLSK 419 Query: 422 IQERFDVKIAEF 433 I + D + +F Sbjct: 420 ILRQADQSVPDF 431 >3JCR-F nrPDB Length = 820 Score = 183 bits (464), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 121/408 (29%), Positives = 205/408 (50%), Gaps = 44/408 (10%) Query: 53 KGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGK 112 KG + +KD L P + I CG++ P+ +Q+ IP + D++ A++G GK Sbjct: 382 KGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGK 441 Query: 113 TAVFVLSTLQQLDPVP----------GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKT 162 TA F++ L + +P G A++ + RELA QI E ++F K + ++T Sbjct: 442 TAAFLIPLLVWITTLPKIDRIEESDQGPYAII-LAPTRELAQQIEEETIKFGKPL-GIRT 499 Query: 163 AVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLE 222 GG IS++ + + + IV+ATPGRL ++ +Y+ LS V+DE D++++ Sbjct: 500 VAVIGG--ISREDQGFRLR-MGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMID 556 Query: 223 ELDMRRDVQEIFRATP--------------------------RDKQVMMFSATLSQEIRP 256 + DVQ+I P + +Q +MF+AT+ + Sbjct: 557 -MGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVER 615 Query: 257 ICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKST 316 + R +L+ P +++ K Q+ ++ + E EK +KL +L+ +IIFV Sbjct: 616 LARSYLRRPAVVYIGSAGKPHERVEQKVFL-MSESEKRKKLLAILEQGFDPPIIIFVNQK 674 Query: 317 TRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERIN 376 + L K L + A T+HG QE+R K K I V+TDV GRGIDI+ ++ Sbjct: 675 KGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVS 734 Query: 377 LAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQE 424 + +NYD+ + Y+HR+GR GR G G+AI+F+ +KED V ++++ Sbjct: 735 MVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFL-TKEDSAVFYELKQ 781 >2DB3-A nrPDB Length = 434 Score = 179 bits (454), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 123/380 (32%), Positives = 198/380 (52%), Gaps = 39/380 (10%) Query: 72 ELSRAIID----CGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPV 127 +L IID G++ P+ +Q+ +IP G D++ A++G GKTA F+L L +L Sbjct: 62 DLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLED 121 Query: 128 P-----GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKD 182 P G VV++ RELA QI NE +F+ + +K + YGGT E + Sbjct: 122 PHELELGRPQVVIVSPTRELAIQIFNEARKFA-FESYLKIGIVYGGTSFRHQNECITR-- 178 Query: 183 TAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLE---ELDMRRDVQEIFRATPR 239 H+V+ATPGRL V +I + V+DE D++L+ DMRR + + T R Sbjct: 179 -GCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHV---TMR 234 Query: 240 -DKQVMMFSATLSQEIRPICRRFLQNPLEIFVD------DEAKLTLHGLQQYYIKLEERE 292 + Q +MFSAT +EI+ + FL+N + + + + K T++ + +Y Sbjct: 235 PEHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVNKY-------A 287 Query: 293 KNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAF 352 K KL ++L + + + I+FV++ A+ L L+ FP ++HG Q +R + F Sbjct: 288 KRSKLIEILSE-QADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDF 346 Query: 353 KDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSS 412 K+ ++ ++T V RG+DI+ I INYD+ ++ D Y+HR+GR GR G G A SF Sbjct: 347 KNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDP 406 Query: 413 KEDEEVLAKIQERFDVKIAE 432 ++D + A + VKI E Sbjct: 407 EKDRAIAADL-----VKILE 421 >4KBG-A nrPDB Length = 365 Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 108/333 (32%), Positives = 177/333 (53%), Gaps = 15/333 (4%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 FKDF LKPE+ A+ G P+ +Q +P ++ G D++ QA++G GKT F L ++ Sbjct: 3 FKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAER 62 Query: 124 LDPVP---GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAE-LLK 179 L P + +V+ RELA Q+ +E + P +K YGGT K E LL+ Sbjct: 63 LAPSQERGRKPRALVLTPTRELALQVASE---LTAVAPHLKVVAVYGGTGYGKQKEALLR 119 Query: 180 NKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPR 239 D VVATPGR +R+ +DLS V+ V+DE D++L + +V+ + ATP Sbjct: 120 GADA----VVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLS-MGFEEEVEALLSATPP 174 Query: 240 DKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQ 299 +Q ++FSATL + + R+++NP+ I V + +T ++ + R + L+ Sbjct: 175 SRQTLLFSATLPSWAKRLAERYMKNPVLINVIKDEPVTY---EEEAVPAPVRGRLEVLSD 231 Query: 300 LLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRI 359 LL ++ ++F ++ E+ + L PA +HG + Q ER AF+ E R+ Sbjct: 232 LLYVASPDRAMVFTRTKAETEEIAQGLLRLGHPAQALHGDLSQGERERVLGAFRQGEVRV 291 Query: 360 CVSTDVFGRGIDIERINLAINYDLTNEADQYLH 392 V+TDV RG+DI +++L ++Y L + A+ Y H Sbjct: 292 LVATDVAARGLDIPQVDLVVHYRLPDRAEAYQH 324 >3FHO-A nrPDB Length = 508 Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 112/359 (31%), Positives = 188/359 (52%), Gaps = 18/359 (5%) Query: 87 EVQQHTIPQSIHGT--DVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAY 144 ++Q+ +P + +++ Q++SG GKTA F L+ L ++D + + + +RELA Sbjct: 144 KIQEKALPLLLSNPPRNMIGQSQSGTGKTAAFALTMLSRVDASVPKPQAICLAPSRELAR 203 Query: 145 QIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYI 204 QI + KY +VKTA F + K A++ IV+ TPG + L++ + + Sbjct: 204 QIMDVVTEMGKYT-EVKTA-FGIKDSVPKGAKI------DAQIVIGTPGTVMDLMKRRQL 255 Query: 205 DLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQN 264 D +K FV+DE D +L++ + I PR+ Q+++FSAT S+ + RF N Sbjct: 256 DARDIKVFVLDEADNMLDQQGLGDQSMRIKHLLPRNTQIVLFSATFSERVEKYAERFAPN 315 Query: 265 PLEIFVDDEAKLTLHGLQQYYIKLEERE-KNRKLAQLLDDLEFNQVIIFVKSTTRANELT 323 EI + E +L++ G++Q Y+ + E K L +L L Q IIF K A E+ Sbjct: 316 ANEIRLKTE-ELSVEGIKQLYMDCQSEEHKYNVLVELYGLLTIGQSIIFCKKKDTAEEIA 374 Query: 324 KLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDL 383 + + A + G+++ +R A +F+ ++ V+T+V RGID+ ++NL +NYD+ Sbjct: 375 RRMTADGHTVACLTGNLEGAQRDAIMDSFRVGTSKVLVTTNVIARGIDVSQVNLVVNYDM 434 Query: 384 T------NEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPEE 436 + YLHR+GR GRFG G++I+FV K+ E + IQE F I P + Sbjct: 435 PLDQAGRPDPQTYLHRIGRTGRFGRVGVSINFVHDKKSWEEMNAIQEYFQRPITRVPTD 493 >2Z0M-A nrPDB Length = 337 Score = 173 bits (438), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 113/342 (33%), Positives = 185/342 (54%), Gaps = 22/342 (6%) Query: 69 LKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVP 128 + ++ +AI + GF++ +EVQ TIP + G +V+ +AK+G GKTA + + L+ Sbjct: 1 MNEKIEQAIREMGFKNFTEVQSKTIPLMLQGKNVVVRAKTGSGKTAAYAIPILEL----- 55 Query: 129 GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIV 188 + +V+ REL Q+ + +YM D K A YGG P ++N D IV Sbjct: 56 -GMKSLVVTPTRELTRQVASHIRDIGRYM-DTKVAEVYGGMPYKAQINRVRNAD----IV 109 Query: 189 VATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSA 248 VATPGRL L + IDLS + +IDE D ++ E+ D++ I T K +FSA Sbjct: 110 VATPGRLLDLWSKGVIDLSSFEIVIIDEAD-LMFEMGFIDDIKIILAQTSNRKITGLFSA 168 Query: 249 TLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQ 308 T+ +EIR + + F+ N EI EA + L ++ ++ +++ +++ Q L + + Sbjct: 169 TIPEEIRKVVKDFITNYEEI----EACIGLANVEHKFVHVKDDWRSK--VQALRENKDKG 222 Query: 309 VIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGR 368 VI+FV++ R +L +L + AI + G + Q R AF++ E + ++TDV R Sbjct: 223 VIVFVRTRNRVAKLVRLFDN----AIELRGDLPQSVRNRNIDAFREGEYDMLITTDVASR 278 Query: 369 GIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFV 410 G+DI + IN+D + Y+HR+GR GR G KG AI+F+ Sbjct: 279 GLDIPLVEKVINFDAPQDLRTYIHRIGRTGRMGRKGEAITFI 320 >6CZ5-A nrPDB Length = 480 Score = 164 bits (416), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 112/354 (31%), Positives = 177/354 (50%), Gaps = 27/354 (7%) Query: 82 FEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQL-DPVPGEV--------- 131 + P+ VQ+H IP D++ A++G GKTA F+L L Q+ PGE Sbjct: 73 YTRPTPVQKHAIPIIKEKRDLMACAQTGCGKTAAFLLPILSQIYSDGPGEALRAMKENGR 132 Query: 132 --------AVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 +V+ RELA QI E +FS Y V+ V YGG I + +++ + Sbjct: 133 YGRRKQYPISLVLAPTRELAVQIYEEARKFS-YRSRVRPCVVYGGADIGQQ---IRDLER 188 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLE---ELDMRRDVQEIFRATPRD 240 H++VATPGRL ++ I L K V+DE D++L+ E +RR V++ Sbjct: 189 GCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGV 248 Query: 241 KQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQL 300 + MMFSAT +EI+ + R FL + + V T + Q + +EE +K L L Sbjct: 249 RHTMMFSATFPKEIQMLARDFLDEYIFLAVG-RVGSTSENITQKVVWVEESDKRSFLLDL 307 Query: 301 LDDLEFNQV-IIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRI 359 L+ + + ++FV++ A+ L L + ++HG Q +R F+ + I Sbjct: 308 LNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPI 367 Query: 360 CVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSK 413 V+T V RG+DI + IN+DL ++ ++Y+HR+GR GR G GLA SF + + Sbjct: 368 LVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNER 421 >2I4I-A nrPDB Length = 417 Score = 163 bits (413), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 112/354 (31%), Positives = 177/354 (50%), Gaps = 27/354 (7%) Query: 82 FEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQL-DPVPGEV--------- 131 + P+ VQ+H IP D++ A++G GKTA F+L L Q+ PGE Sbjct: 35 YTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGR 94 Query: 132 --------AVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 +V+ RELA QI E +FS Y V+ V YGG I + +++ + Sbjct: 95 YGRRKQYPISLVLAPTRELAVQIYEEARKFS-YRSRVRPCVVYGGADIGQQ---IRDLER 150 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLE---ELDMRRDVQEIFRATPRD 240 H++VATPGRL ++ I L K V+DE D++L+ E +RR V++ Sbjct: 151 GCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGV 210 Query: 241 KQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQL 300 + MMFSAT +EI+ + R FL + + V T + Q + +EE +K L L Sbjct: 211 RHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGS-TSENITQKVVWVEESDKRSFLLDL 269 Query: 301 LDDLEFNQV-IIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRI 359 L+ + + ++FV++ A+ L L + ++HG Q +R F+ + I Sbjct: 270 LNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPI 329 Query: 360 CVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSK 413 V+T V RG+DI + IN+DL ++ ++Y+HR+GR GR G GLA SF + + Sbjct: 330 LVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNER 383 >5DTU-A nrPDB Length = 475 Score = 158 bits (400), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 106/404 (26%), Positives = 199/404 (49%), Gaps = 47/404 (11%) Query: 73 LSRAIID----CGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVP 128 L R ++D G++ P+ +Q+ IP ++ D++ A +G GKTA F+L L + +P Sbjct: 49 LPRRLLDIVYRVGYDEPTPIQRAAIPIALQARDLIGVAVTGSGKTAAFLLPLLVYISELP 108 Query: 129 ---------GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLK 179 G A++ + REL QI +E +F+ + GG + + A L+ Sbjct: 109 PLTEYNKNDGPYALI-LAPTRELVQQIESEARKFADPL-GFTVVSIVGGHSLEEQAFALR 166 Query: 180 NKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATP- 238 N I+VATPGRL + + + S ++DE D+++++ + +I A P Sbjct: 167 N---GAEIIVATPGRLVDCIERRLLVFSQCCYVIMDEADRMIDQ-GFEEPLTKILDALPV 222 Query: 239 ------------------------RDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEA 274 R +Q MM++AT+ + I +++L+ P + + + Sbjct: 223 SNEKPDTEDAENPQLMSRYLGGRDRYRQTMMYTATMPPTVEKIAKKYLRRPAIVTIGNAG 282 Query: 275 KLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQ-VIIFVKSTTRANELTKLLNASNFPA 333 + Q+ E ++ R+L ++L+ +F +I+FV + K + + F Sbjct: 283 EAVDTVEQRVEFIAGEDKRKRRLQEILNSGQFKPPIIVFVNIKRNCEMVAKDIKSWGFST 342 Query: 334 ITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHR 393 +T+HG QE+R A A ++ + I V+TD+ GRGID+ ++L +N+++ + + Y HR Sbjct: 343 VTLHGSKTQEQREASLAALRNGQAHILVATDLAGRGIDVPDVSLVVNFNMPSTIEAYTHR 402 Query: 394 VGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFD-VKIAEFPEE 436 +GR GR G G+AI+F+ + ED +V+ +++ I++ PEE Sbjct: 403 IGRTGRAGKSGVAITFLGN-EDADVMYDLKQIISKSSISKVPEE 445 >6CB1-p nrPDB Length = 505 Score = 151 bits (382), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 121/389 (31%), Positives = 191/389 (49%), Gaps = 24/389 (6%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F++ L +AI GF + VQ TIP + G DVL AK+G GKT F++ ++ Sbjct: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 Query: 124 L-----DPVPGEVAVVVICNARELAYQI---RNEYLRFSKYMPDVKTAVFYGGTPISKDA 175 L P G ++VI RELA QI E + F + GG ++A Sbjct: 104 LHSLKFKPRNG-TGIIVITPTRELALQIFGVARELMEFHSQT----FGIVIGGANRRQEA 158 Query: 176 ELLKNKDTAPHIVVATPGRL-KALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIF 234 E L ++++ATPGRL L K ++K +IDE D++LE + ++++I Sbjct: 159 EKLMK---GVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQII 214 Query: 235 RATPR-DKQVMMFSATLSQEIRPICRRFLQ-NPLEIFVDDEA-KLTLHGLQQYYIKLEER 291 + P D+Q M+FSAT + ++ + R L+ PL I V E T GL+Q Y+ + Sbjct: 215 KILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSD 274 Query: 292 EKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKA 351 ++ L L + ++I+F+ S +LLN + P + +HG KQ++R + Sbjct: 275 KRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFE 334 Query: 352 FKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVS 411 F + E+ I + TDV RG+DI ++ I +D ++ Y+HRVGR R GTKG S + Sbjct: 335 FCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR-GTKGKGKSLMF 393 Query: 412 SKEDEEVLAKIQERFDVKIA--EFPEEGI 438 +E + + V + EFPE I Sbjct: 394 LTPNELGFLRYLKASKVPLNEYEFPENKI 422 >5GJU-A nrPDB Length = 205 Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 81/209 (38%), Positives = 112/209 (53%), Gaps = 4/209 (1%) Query: 62 TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 T F D LK + A+ D G+E PS +Q IP ++G DVL A++G GKTA F L L Sbjct: 1 TTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLL 60 Query: 122 QQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNK 181 Q LDP ++V+ RELA Q+ FSK+M V YGG D + L+ Sbjct: 61 QNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQ--RYDVQ-LRAL 117 Query: 182 DTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDK 241 P IVV TPGRL ++ +DLS + V+DE D++L + DV+ I P Sbjct: 118 RQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADEML-RMGFIEDVETIMAQIPEGH 176 Query: 242 QVMMFSATLSQEIRPICRRFLQNPLEIFV 270 Q +FSAT+ + IR I RRF++ P E+ + Sbjct: 177 QTALFSATMPEAIRRITRRFMKEPQEVRI 205 >3BOR-A nrPDB Length = 237 Score = 138 bits (347), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 81/210 (38%), Positives = 116/210 (55%), Gaps = 4/210 (1%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F D LK L R I GFE PS +QQ I I G DV+ QA+SG GKTA F +S LQQ Sbjct: 32 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 91 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 L+ E +V+ RELA QI+ L YM A GGT + E+ K + Sbjct: 92 LEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACI-GGTNVRN--EMQKLQAE 148 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 APHIVV TPGR+ ++ +Y+ +K FV+DE D++L + + EIF+ QV Sbjct: 149 APHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSR-GFKDQIYEIFQKLNTSIQV 207 Query: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDE 273 ++ SAT+ ++ + ++F+++P+ I V E Sbjct: 208 VLLSATMPTDVLEVTKKFMRDPIRILVKKE 237 >5ZWN-y nrPDB Length = 588 Score = 137 bits (345), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 105/378 (27%), Positives = 187/378 (49%), Gaps = 34/378 (8%) Query: 72 ELSRAII-DCGFEHPSEVQQHTIPQSIHGT---DVLCQAKSGLGKTAVFVLSTLQQLD-- 125 +L R II + F P+ +Q+ TIP + D L A +G GKT FV+ L ++ Sbjct: 183 DLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPILIKMSRS 242 Query: 126 -PVPGEVAVV------VICNARELAYQIRNEYLRFSKYMP-----DVKTAVFYGGTPISK 173 P P + ++ ++ REL QI+ E + +K D K GG + Sbjct: 243 PPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLE- 301 Query: 174 DAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEI 233 E+ + I+VATPGRL + + + V+ V+DE DK+++ L V I Sbjct: 302 --EISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLDEADKMID-LGFEDQVTNI 358 Query: 234 FRA------TPRDKQVMMFSATLSQEIRPICRRFLQNPL--EIFVDDEAKLTLHGLQQYY 285 + ++Q +MF+AT++ I I ++Q P+ I V+ ++ + + +Y Sbjct: 359 LTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVYATIGVETGSEPLIQQVVEY- 417 Query: 286 IKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELT-KLLNASNFPAITVHGHMKQEE 344 + +K +KL ++ + +IIF+ A+ L K +N +HG QE+ Sbjct: 418 -ADNDEDKFKKLKPIVAKYD-PPIIIFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQ 475 Query: 345 RIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKG 404 R + F+ + +I ++T+V RG+DI ++L +N+ ++ + D Y+HR+GR GR +G Sbjct: 476 REHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDYIHRIGRTGRAANEG 535 Query: 405 LAISFVSSKEDEEVLAKI 422 A+SFVS+ EDE ++ ++ Sbjct: 536 TAVSFVSAAEDESLIREL 553 >4W7S-A nrPDB Length = 463 Score = 137 bits (345), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 105/375 (28%), Positives = 185/375 (49%), Gaps = 34/375 (9%) Query: 72 ELSRAII-DCGFEHPSEVQQHTIPQSIHGT---DVLCQAKSGLGKTAVFVLSTLQQLD-- 125 +L R II + F P+ +Q+ TIP + D L A +G GKT FV+ L ++ Sbjct: 58 DLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPILIKMSRS 117 Query: 126 -PVPGEVAVV------VICNARELAYQIRNEYLRFSKYMP-----DVKTAVFYGGTPISK 173 P P + ++ ++ REL QI+ E + +K D K GG + Sbjct: 118 PPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLE- 176 Query: 174 DAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEI 233 E+ + I+VATPGRL + + + V+ V+DE DK+++ L V I Sbjct: 177 --EISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLDEADKMID-LGFEDQVTNI 233 Query: 234 FRA------TPRDKQVMMFSATLSQEIRPICRRFLQNPL--EIFVDDEAKLTLHGLQQYY 285 + ++Q +MF+AT++ I I ++Q P+ I V+ ++ + + +Y Sbjct: 234 LTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVYATIGVETGSEPLIQQVVEY- 292 Query: 286 IKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELT-KLLNASNFPAITVHGHMKQEE 344 + +K +KL ++ + +IIF+ A+ L K +N +HG QE+ Sbjct: 293 -ADNDEDKFKKLKPIVAKYD-PPIIIFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQ 350 Query: 345 RIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKG 404 R + F+ + +I ++T+V RG+DI ++L +N+ ++ + D Y+HR+GR GR +G Sbjct: 351 REHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDYIHRIGRTGRAANEG 410 Query: 405 LAISFVSSKEDEEVL 419 A+SFVS+ EDE ++ Sbjct: 411 TAVSFVSAAEDESLI 425 >1VEC-A nrPDB Length = 206 Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 69/205 (33%), Positives = 122/205 (59%), Gaps = 4/205 (1%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F+D+ LK EL I + G+E PS +Q+ +IP ++ G D+L +AK+G GK+ +++ L++ Sbjct: 5 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 64 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 LD + +VI RELA Q+ ++ SK+M K GGT + D +++ DT Sbjct: 65 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDD--IMRLDDT 122 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 H+V+ATPGR+ L+++ + HV+ V+DE DK+L + D + +++I P+++Q+ Sbjct: 123 V-HVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMEDIILTLPKNRQI 180 Query: 244 MMFSATLSQEIRPICRRFLQNPLEI 268 +++SAT ++ L+ P EI Sbjct: 181 LLYSATFPLSVQKFMNSHLEKPYEI 205 >5ZBZ-A nrPDB Length = 220 Score = 131 bits (330), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 75/207 (36%), Positives = 116/207 (56%), Gaps = 4/207 (1%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F D L L R I GFE PS +QQ I I G DV+ QA+SG GKTA F +S LQQ Sbjct: 16 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 75 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 ++ +V+ RELA QI+ + YM A GGT + AE+ K + Sbjct: 76 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACI-GGTNVR--AEVQKLQME 132 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 APHI+V TPGR+ ++ +Y+ ++K FV+DE D++L + + +IF+ + QV Sbjct: 133 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQV 191 Query: 244 MMFSATLSQEIRPICRRFLQNPLEIFV 270 ++ SAT+ ++ + ++F+++P+ I V Sbjct: 192 VLLSATMPSDVLEVTKKFMRDPIRILV 218 >1Q0U-A nrPDB Length = 219 Score = 129 bits (323), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 70/212 (33%), Positives = 121/212 (57%), Gaps = 7/212 (3%) Query: 62 TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 T F F +P + AI F P+E+Q+ IP ++ G ++ Q+++G GKT ++L + Sbjct: 4 TQFTRFPFQPFIIEAIKTLRFYKPTEIQERIIPGALRGESMVGQSQTGTGKTHAYLLPIM 63 Query: 122 QQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAV---FYGGTPISKDAELL 178 +++ P EV V+ RELA QI +E L+ +K+ P + V GGT K E L Sbjct: 64 EKIKPERAEVQAVITAPTRELATQIYHETLKITKFCPKDRMIVARCLIGGTDKQKALEKL 123 Query: 179 KNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATP 238 + PHIV+ TPGR+ +RE+ +D+ V+DE D +L ++ DV +I P Sbjct: 124 ---NVQPHIVIGTPGRINDFIREQALDVHTAHILVVDEADLML-DMGFITDVDQIAARMP 179 Query: 239 RDKQVMMFSATLSQEIRPICRRFLQNPLEIFV 270 +D Q+++FSAT+ ++++P +++++NP + V Sbjct: 180 KDLQMLVFSATIPEKLKPFLKKYMENPTFVHV 211 >4LJY-A nrPDB Length = 493 Score = 128 bits (322), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 96/359 (26%), Positives = 167/359 (46%), Gaps = 35/359 (9%) Query: 82 FEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLD---PVP----GEVAVV 134 F + +Q +P + G DV+ +K+G GKT ++L L+Q+ P+ G + ++ Sbjct: 71 FGSLTPIQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGLI 130 Query: 135 VICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGR 194 + RELA QI E +F++ +++ GG+ + K LK IVVATPGR Sbjct: 131 -LAPTRELALQIHEEVTKFTEADTSIRSVCCTGGSEMKKQITDLKR---GTEIVVATPGR 186 Query: 195 ---LKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLS 251 + L K + + V+DE D++ + L + +I + DKQ ++FSAT Sbjct: 187 FIDILTLNDGKLLSTKRITFVVMDEADRLFD-LGFEPQITQIMKTVRPDKQCVLFSATFP 245 Query: 252 QEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLE--FNQV 309 ++R R L +P+ I ++ + + + Q++ I E EK L QL+ + F++V Sbjct: 246 NKLRSFAVRVLHSPISITINSKGMVNENVKQKFRICHSEDEKFDNLVQLIHERSEFFDEV 305 Query: 310 ------------------IIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKA 351 IIFV S + ++K L + +H +ER+ + Sbjct: 306 QSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKPYQERLMNLEK 365 Query: 352 FKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFV 410 FK + I + T+V RG+++ ++L I Y+ QY+H GR R G AI+ + Sbjct: 366 FKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRSGTAITLL 424 >2GXQ-A nrPDB Length = 207 Score = 126 bits (317), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 75/211 (35%), Positives = 116/211 (54%), Gaps = 12/211 (5%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 FKDF LKPE+ A+ G P+ +Q +P ++ G D++ QA++G GKT F L ++ Sbjct: 3 FKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAER 62 Query: 124 LDPVP---GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAE-LLK 179 L P + +V+ RELA Q+ +E + P +K YGGT K E LL+ Sbjct: 63 LAPSQERGRKPRALVLTPTRELALQVASE---LTAVAPHLKVVAVYGGTGYGKQKEALLR 119 Query: 180 NKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPR 239 D VVATPGR +R+ +DLS V+ V+DE D++L + +V+ + ATP Sbjct: 120 GADA----VVATPGRALDYLRQGVLDLSRVEVAVLDEADEML-SMGFEEEVEALLSATPP 174 Query: 240 DKQVMMFSATLSQEIRPICRRFLQNPLEIFV 270 +Q ++FSATL + + R+++NP+ I V Sbjct: 175 SRQTLLFSATLPSWAKRLAERYMKNPVLINV 205 >1QVA-A nrPDB Length = 223 Score = 124 bits (312), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 71/207 (34%), Positives = 112/207 (54%), Gaps = 6/207 (2%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F D L +L R + GFE PS +QQ I I G DVL QA+SG GKT F ++ LQ+ Sbjct: 23 FDDMELDEQLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQR 82 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 +D +++ RELA QI+ + + +M D+K GGT +DAE L++ Sbjct: 83 IDTSVKAPQALMLAPTRELALQIQKVVMALAFHM-DIKVHACIGGTSFVEDAEGLRDA-- 139 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 IVV TPGR+ ++ + +K F++DE D++L + + +IF P QV Sbjct: 140 --QIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSS-GFKEQIYQIFTLLPPTTQV 196 Query: 244 MMFSATLSQEIRPICRRFLQNPLEIFV 270 ++ SAT+ ++ + +F++NP+ I V Sbjct: 197 VLLSATMPNDVLEVTTKFMRNPVRILV 223 >3BER-A nrPDB Length = 249 Score = 119 bits (297), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 70/209 (33%), Positives = 116/209 (55%), Gaps = 8/209 (3%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 FKD + L A G+ P+++Q IP ++ G D++ A++G GKT F L L Sbjct: 45 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 104 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGT-PISKDAELLKNKD 182 L P + +V+ RELA+QI ++ + V++AV GG +S+ L K Sbjct: 105 LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK-- 161 Query: 183 TAPHIVVATPGRL-KALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDK 241 PHI++ATPGRL L K +L +K V+DE D++L +D +V +I + PRD+ Sbjct: 162 --PHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL-NMDFETEVDKILKVIPRDR 218 Query: 242 QVMMFSATLSQEIRPICRRFLQNPLEIFV 270 + +FSAT++++++ + R L+NP++ V Sbjct: 219 KTFLFSATMTKKVQKLQRAALKNPVKCAV 247 >2OXC-A nrPDB Length = 230 Score = 117 bits (293), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 4/202 (1%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F+ LL + + GFE PS VQ IP G D++ QAKSG GKT VF L Sbjct: 26 FESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDS 85 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 L ++++ RE+A QI + M ++ VF GGTP+S+D LK Sbjct: 86 LVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKC-- 143 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 HI V +PGR+K L+ Y++ ++ F++DE DK+LEE + + I+ + P KQ+ Sbjct: 144 --HIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQM 201 Query: 244 MMFSATLSQEIRPICRRFLQNP 265 + SAT + + +++++P Sbjct: 202 LAVSATYPEFLANALTKYMRDP 223 >3SQW-A nrPDB Length = 579 Score = 112 bits (279), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 104/377 (27%), Positives = 171/377 (45%), Gaps = 34/377 (9%) Query: 68 LLKPELSRAIIDCGFEHPSEVQQHTIPQ--SIHGTDVLCQAKSGLGKTAVFVLSTLQQLD 125 +L E+ +AI F + VQQ TI S DV+ +AK+G GKT F++ Q L Sbjct: 27 VLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLI 86 Query: 126 PVPGE----VAVVVICNARELAYQIRNEYLRFSKYMPDVK---TAVFYGGTPISKDAELL 178 + V V++ R+LA QI E + +K GGT A + Sbjct: 87 NTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFR--AAMN 144 Query: 179 KNKDTAPHIVVATPGRLKALVREKYID--LSHVKNFVIDECDKVLEELDMRRDVQEIF-- 234 K P+IV+ATPGRL ++ EKY + V V+DE D++LE + R D++ I Sbjct: 145 KMNKLRPNIVIATPGRLIDVL-EKYSNKFFRFVDYKVLDEADRLLE-IGFRDDLETISGI 202 Query: 235 -----RATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVD--DEAKLTLHGLQQYYIK 287 + + + ++FSATL +++ + + +F+D D+ + H + Sbjct: 203 LNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVV 262 Query: 288 LEEREKNRKLA-------QLLDDLEFNQVIIFVKSTTRANELTKLLN---ASNFPAITVH 337 + E+ N A Q+ + + IIF + + L +L + P + H Sbjct: 263 ISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFH 322 Query: 338 GHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRA 397 G + Q +R + K FK E I V TDV RG+D ++ + + +E Y+HR+GR Sbjct: 323 GKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRT 382 Query: 398 GRFGTKGLAISFVSSKE 414 R G +G ++ F+ E Sbjct: 383 ARSGKEGSSVLFICKDE 399 >3I62-A nrPDB Length = 563 Score = 112 bits (279), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 104/377 (27%), Positives = 171/377 (45%), Gaps = 34/377 (9%) Query: 68 LLKPELSRAIIDCGFEHPSEVQQHTIPQ--SIHGTDVLCQAKSGLGKTAVFVLSTLQQLD 125 +L E+ +AI F + VQQ TI S DV+ +AK+G GKT F++ Q L Sbjct: 78 VLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLI 137 Query: 126 PVPGE----VAVVVICNARELAYQIRNEYLRFSKYMPDVK---TAVFYGGTPISKDAELL 178 + V V++ R+LA QI E + +K GGT A + Sbjct: 138 NTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFR--AAMN 195 Query: 179 KNKDTAPHIVVATPGRLKALVREKYID--LSHVKNFVIDECDKVLEELDMRRDVQEIF-- 234 K P+IV+ATPGRL ++ EKY + V V+DE D++LE + R D++ I Sbjct: 196 KMNKLRPNIVIATPGRLIDVL-EKYSNKFFRFVDYKVLDEADRLLE-IGFRDDLETISGI 253 Query: 235 -----RATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVD--DEAKLTLHGLQQYYIK 287 + + + ++FSATL +++ + + +F+D D+ + H + Sbjct: 254 LNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVV 313 Query: 288 LEEREKNRKLA-------QLLDDLEFNQVIIFVKSTTRANELTKLLN---ASNFPAITVH 337 + E+ N A Q+ + + IIF + + L +L + P + H Sbjct: 314 ISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFH 373 Query: 338 GHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRA 397 G + Q +R + K FK E I V TDV RG+D ++ + + +E Y+HR+GR Sbjct: 374 GKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRT 433 Query: 398 GRFGTKGLAISFVSSKE 414 R G +G ++ F+ E Sbjct: 434 ARSGKEGSSVLFICKDE 450 >6AIC-A nrPDB Length = 214 Score = 102 bits (254), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 57/203 (28%), Positives = 111/203 (54%), Gaps = 7/203 (3%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 FK+ + +++ GF+ P+ +Q+ +IP ++ G D+L QA++G GKT F + +++ Sbjct: 4 FKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPLIEK 63 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 + G V +++ RELA Q+ + FS+ V+ +GG PI + + LK Sbjct: 64 VVGKQG-VQSLILAPTRELAMQVAEQLREFSRGQ-GVQVVTVFGGMPIERQIKALKK--- 118 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPR-DKQ 242 P IVV TPGR+ + + + + ++DE D+++ + D++ I P +Q Sbjct: 119 GPQIVVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMM-NMGFIDDMRFIMDKIPAVQRQ 177 Query: 243 VMMFSATLSQEIRPICRRFLQNP 265 M+FSAT+ + I+ + ++F+++P Sbjct: 178 TMLFSATMPKAIQALVQQFMKSP 200 >2KBE-A nrPDB Length = 226 Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 61/209 (29%), Positives = 108/209 (51%), Gaps = 16/209 (7%) Query: 61 STGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGT--DVLCQAKSGLGKTAVFVL 118 + F + L PEL + I F+ PS++Q+ +P +H +++ Q++SG GKTA F L Sbjct: 21 AKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSL 80 Query: 119 STLQQLDPVPGEVAVVVICNARELAYQ---IRNEYLRFSKYMPDVKTAVFYGGTPISKDA 175 + L +++P + + +RELA Q + E +F+K + I D+ Sbjct: 81 TMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQL----------IVPDS 130 Query: 176 ELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFR 235 KNK ++V TPG + L+R K + L +K FV+DE D +L++ + + R Sbjct: 131 -FEKNKQINAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKR 189 Query: 236 ATPRDKQVMMFSATLSQEIRPICRRFLQN 264 P+D Q+++FSAT + +R ++ + N Sbjct: 190 FLPKDTQLVLFSATFADAVRQYAKKIVPN 218 >3FMO-B nrPDB Length = 300 Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 62/227 (27%), Positives = 110/227 (48%), Gaps = 9/227 (3%) Query: 42 DNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIH--G 99 DN N + + F++ LKP+L + + GF PS++Q++ +P + Sbjct: 72 DNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPP 131 Query: 100 TDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPD 159 +++ Q++SG GKTA FVL+ L Q++P + + ELA Q + K+ P+ Sbjct: 132 QNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPE 191 Query: 160 VKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGR-LKALVREKYIDLSHVKNFVIDECD 218 +K A G +L + + + IV+ TPG L + K+ID +K FV+DE D Sbjct: 192 LKLAYAVRGN------KLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 245 Query: 219 KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNP 265 ++ + I R PR+ Q+++FSAT + ++ + +P Sbjct: 246 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDP 292 >1WRB-A nrPDB Length = 253 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 62/213 (29%), Positives = 109/213 (51%), Gaps = 16/213 (7%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL-- 121 F + L P + I+ ++ P+ +Q++ IP + D++ A++G GKTA F++ + Sbjct: 25 FDELKLDPTIRNNILLASYQRPTPIQKNAIPAILEHRDIMACAQTGSGKTAAFLIPIINH 84 Query: 122 -------QQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKD 174 QQ +++ RELA QI +E +FS P +++ V YGG + Sbjct: 85 LVCQDLNQQRYSKTAYPKCLILAPTRELAIQILSESQKFSLNTP-LRSCVVYGG---ADT 140 Query: 175 AELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLE---ELDMRRDVQ 231 ++ H++VATPGRL + + I L K V+DE D++L+ E +R+ ++ Sbjct: 141 HSQIREVQMGCHLLVATPGRLVDFIEKNKISLEFCKYIVLDEADRMLDMGFEPQIRKIIE 200 Query: 232 EIFRATPRDKQVMMFSATLSQEIRPICRRFLQN 264 E + ++Q +MFSAT +EI+ + FL N Sbjct: 201 ESNMPSGINRQTLMFSATFPKEIQKLAADFLYN 233 >3FHC-B nrPDB Length = 235 Score = 96.3 bits (238), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 62/227 (27%), Positives = 110/227 (48%), Gaps = 9/227 (3%) Query: 42 DNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSI--HG 99 DN N + + F++ LKP+L + + GF PS++Q++ +P + Sbjct: 5 DNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPP 64 Query: 100 TDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPD 159 +++ Q++SG GKTA FVL+ L Q++P + + ELA Q + K+ P+ Sbjct: 65 QNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPE 124 Query: 160 VKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGR-LKALVREKYIDLSHVKNFVIDECD 218 +K A G +L + + + IV+ TPG L + K+ID +K FV+DE D Sbjct: 125 LKLAYAVRGN------KLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 178 Query: 219 KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNP 265 ++ + I R PR+ Q+++FSAT + ++ + +P Sbjct: 179 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDP 225 >4PX9-A nrPDB Length = 292 Score = 95.9 bits (237), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 68/202 (33%), Positives = 101/202 (50%), Gaps = 25/202 (12%) Query: 82 FEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQL-DPVPGEV--------- 131 + P+ VQ+H IP D++ A++G GKTA F+L L Q+ PGE Sbjct: 85 YTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGR 144 Query: 132 --------AVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 +V+ RELA QI E +FS Y V+ V YGG I + +++ + Sbjct: 145 YGRRKQYPISLVLAPTRELAVQIYEEARKFS-YRSRVRPCVVYGGADIGQQ---IRDLER 200 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLE---ELDMRRDVQEIFRATPRD 240 H++VATPGRL ++ I L K V+DE D++L+ E +RR V++ Sbjct: 201 GCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGV 260 Query: 241 KQVMMFSATLSQEIRPICRRFL 262 + MMFSAT +EI+ + R FL Sbjct: 261 RHTMMFSATFPKEIQMLARDFL 282 >2PL3-A nrPDB Length = 236 Score = 94.7 bits (234), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 64/218 (29%), Positives = 113/218 (51%), Gaps = 11/218 (5%) Query: 62 TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 T F DF L + + + + + +E+Q+ TI ++ G DVL AK+G GKT F++ L Sbjct: 25 TRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVL 84 Query: 122 QQLDPVPGE----VAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL 177 + L + + V++I RELAYQ E LR D + GG + +AE Sbjct: 85 EALYRLQWTSTDGLGVLIISPTRELAYQTF-EVLRKVGKNHDFSAGLIIGGKDLKHEAER 143 Query: 178 LKNKDTAPHIVVATPGRLKALVREKY-IDLSHVKNFVIDECDKVLEELDMRRDVQEIFRA 236 + N + I+V TPGRL + E + ++ V+DE D++L ++ + + Sbjct: 144 INNIN----ILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRIL-DMGFADTMNAVIEN 198 Query: 237 TPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEA 274 P+ +Q ++FSAT ++ ++ + R L+NP ++V ++A Sbjct: 199 LPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKA 236 >5H1Y-A nrPDB Length = 281 Score = 91.7 bits (226), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 67/233 (28%), Positives = 116/233 (49%), Gaps = 19/233 (8%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLST--- 120 FK+ + R + G HP+ +Q IP + G D++ A +G GKT VF L Sbjct: 54 FKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMF 113 Query: 121 -LQQLDPVP-----GEVAVVVICNARELAYQ---IRNEYLRFSK--YMPDVKTAVFYGGT 169 L+Q +P G ++IC +RELA Q I Y R + P ++ A+ GG Sbjct: 114 CLEQEKRLPFSKREGPYG-LIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGM 172 Query: 170 PISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRD 229 + + E +++ H++VATPGRL L+++K + L + +DE D+++ ++ D Sbjct: 173 SVKEQMETIRH---GVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMI-DMGFEGD 228 Query: 230 VQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQ 282 ++ IF +Q ++FSAT+ ++I+ + L P+ I V +L +Q Sbjct: 229 IRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQ 281 >3IUY-A nrPDB Length = 228 Score = 91.3 bits (225), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 60/214 (28%), Positives = 110/214 (51%), Gaps = 13/214 (6%) Query: 64 FKD-FLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQ 122 FKD F P+L ++II G P+ +Q P + G D++ A++G GKT +++ Sbjct: 21 FKDAFQQYPDLLKSIIRVGILKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFI 80 Query: 123 QLDPVP------GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAE 176 LD P ++V+ RELA + E ++S +K+ YGG +++ + Sbjct: 81 HLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYS--YKGLKSICIYGGR--NRNGQ 136 Query: 177 LLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRA 236 +++ I++ATPGRL L ++L + VIDE DK+L +++ +++I Sbjct: 137 -IEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKML-DMEFEPQIRKILLD 194 Query: 237 TPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFV 270 D+Q +M SAT +R + +L++P+ ++V Sbjct: 195 VRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYV 228 >5GVS-A nrPDB Length = 231 Score = 88.6 bits (218), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 65/221 (29%), Positives = 112/221 (50%), Gaps = 19/221 (8%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLST--- 120 FK+ + R + G HP+ +Q IP + G D++ A +G GKT VF L Sbjct: 15 FKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMF 74 Query: 121 -LQQLDPVP-----GEVAVVVICNARELAYQ---IRNEYLRFSK--YMPDVKTAVFYGGT 169 L+Q +P G ++IC +RELA Q I Y R + P ++ A+ GG Sbjct: 75 CLEQEKRLPFSKREGPYG-LIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGM 133 Query: 170 PISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRD 229 + + E +++ H++VATPGRL L+++K + L + +DE D+++ ++ D Sbjct: 134 SVKEQMETIRH---GVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMI-DMGFEGD 189 Query: 230 VQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFV 270 ++ IF +Q ++FSAT+ ++I+ + L P+ I V Sbjct: 190 IRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 230 >3DKP-A nrPDB Length = 245 Score = 85.5 bits (210), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 63/212 (29%), Positives = 105/212 (49%), Gaps = 9/212 (4%) Query: 65 KDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQL 124 +++ + L + I+D GF+ P+ +Q IP +HG ++L A +G GKT F + L QL Sbjct: 32 QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL 91 Query: 125 -DPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 P ++I RELA QI E ++ S+ + + + +K +K Sbjct: 92 KQPANKGFRALIISPTRELASQIHRELIKISEGT-GFRIHMIHKAAVAAKKFGPKSSKKF 150 Query: 184 APHIVVATPGRLKALVRE--KYIDLSHVKNFVIDECDKVLEE--LDMRRDVQEIFRATPR 239 I+V TP RL L+++ IDL+ V+ V+DE DK+ E+ R + IF A Sbjct: 151 --DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTS 208 Query: 240 DK-QVMMFSATLSQEIRPICRRFLQNPLEIFV 270 K + MFSAT + ++ C+ L N + + + Sbjct: 209 HKVRRAMFSATFAYDVEQWCKLNLDNVISVSI 240 >3FE2-A nrPDB Length = 242 Score = 78.6 bits (192), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 53/196 (27%), Positives = 98/196 (50%), Gaps = 18/196 (9%) Query: 82 FEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVP------GEVAVVV 135 F P+ +Q P ++ G D++ A++G GKT ++L + ++ P G + +V Sbjct: 49 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPIC-LV 107 Query: 136 ICNARELAYQIRN---EYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATP 192 + RELA Q++ EY R + +K+ YGG P +++ + I +ATP Sbjct: 108 LAPTRELAQQVQQVAAEYCRACR----LKSTCIYGGAP---KGPQIRDLERGVEICIATP 160 Query: 193 GRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQ 252 GRL + +L V+DE D++L ++ +++I D+Q +M+SAT + Sbjct: 161 GRLIDFLECGKTNLRRTTYLVLDEADRML-DMGFEPQIRKIVDQIRPDRQTLMWSATWPK 219 Query: 253 EIRPICRRFLQNPLEI 268 E+R + FL++ + I Sbjct: 220 EVRQLAEDFLKDYIHI 235 >3LY5-A nrPDB Length = 262 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 59/201 (29%), Positives = 102/201 (50%), Gaps = 32/201 (15%) Query: 75 RAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQ---QLDPVP-GE 130 +AI + GF + +E+Q +I + G D+L AK+G GKT F++ ++ +L +P Sbjct: 67 KAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNG 126 Query: 131 VAVVVICNARELAYQIRNEYLRFSKYMPDVKT-AVFYGGTPISKDAELLKNKDTAPHIVV 189 V+++ RELA Q + V T + GG+ S +A+ L N +I+V Sbjct: 127 TGVLILSPTRELAMQTFGVLKELMTH--HVHTYGLIMGGSNRSAEAQKLGN---GINIIV 181 Query: 190 ATPGRLKALVREKYIDLSHVKN-----------FVIDECDKVLEELDMRRDVQEIFRATP 238 ATPGRL L H++N VIDE D++L ++ ++++I + P Sbjct: 182 ATPGRL----------LDHMQNTPGFMYKNLQCLVIDEADRIL-DVGFEEELKQIIKLLP 230 Query: 239 RDKQVMMFSATLSQEIRPICR 259 +Q M+FSAT ++++ + R Sbjct: 231 TRRQTMLFSATQTRKVEDLAR 251 >4Q48-A nrPDB Length = 525 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 79/335 (23%), Positives = 127/335 (37%), Gaps = 42/335 (12%) Query: 88 VQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIR 147 VQ + Q G + L +G GK+ + L +L L P G V +I ++ +R Sbjct: 28 VQGEIVQQVAEGGNALVLMPTGGGKSLCYQLPSL--LRPGTGIVVSPLIALMKDQVDTLR 85 Query: 148 NEYLRFSKYMPDVKTAVFYGGTPIS------KDAELLKNKDTAPHIVVATPGRLKALVRE 201 +R A F T + +DA L + D ++ P RL Sbjct: 86 QNGVR----------AAFLNSTLLPHEAREVEDALLRGDLD----LLYVAPERLLMPRTL 131 Query: 202 KYIDLSHVKNFVIDECDKVLEE-LDMRRDVQEI------FRATPRDKQVMMFSATLSQEI 254 ++ + V F IDE V + D R + Q++ F PR + +AT + Sbjct: 132 DLLERAPVALFAIDEAHCVSQWGHDFRPEYQQLSVLAERFPELPR----VALTATADERT 187 Query: 255 RPICRRFLQ---NPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVII 311 R + L+ P + D + QY + L++ K + L + ++ + I+ Sbjct: 188 RADIKSVLRLEDAPQFVSSFDRPNI------QYRVGLKDSPKTQLLHFIREEHPGDAGIV 241 Query: 312 FVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGID 371 + S E K L A A+ H + ER + F + E I +T FG GID Sbjct: 242 YCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLNEEGVIVCATVAFGMGID 301 Query: 372 IERINLAINYDLTNEADQYLHRVGRAGRFGTKGLA 406 + + DL + Y GRAGR G A Sbjct: 302 KPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTA 336 >5V9X-A nrPDB Length = 877 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 95/398 (23%), Positives = 139/398 (34%), Gaps = 88/398 (22%) Query: 73 LSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKT-AVFVLSTLQQLDPV--PG 129 L+R F P+ Q G + L A +G GKT A F+ + + DP P Sbjct: 36 LTREWFTTAFAAPTPAQADAWSAISEGNNTLVIAPTGSGKTLAAFLWAIDRLADPAREPS 95 Query: 130 E------------VAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL 177 + +AV V N R I R P + V G TP ++ + Sbjct: 96 QGTQVLYVSPLKALAVDVERNLRTPLTGITRVAERHGLPAPSITVGVRSGDTPPNQRRAM 155 Query: 178 LKNKDTAPHIVVATPGRLKALVREKYID-LSHVKNFVIDECDKV------------LEEL 224 + N P +++ TP L ++ + L+ V+ ++DE V LE L Sbjct: 156 IANP---PDVLITTPESLFLMLTSAARETLTSVRTVIVDEVHAVAATKRGAHLALSLERL 212 Query: 225 DMRRDVQEIFRATPRDKQVMMFSATLSQEIRPI--CRRFL--QNPLEIFVDDEAKLTLHG 280 D D TP Q + SAT +RP RFL Q P I AK Sbjct: 213 DQLLD-------TP--AQRIGLSAT----VRPPEEVARFLSGQAPTTIVCPPAAKTFDLS 259 Query: 281 LQQYYIKLEEREKNRKLA----QLLDDLE-FNQVIIFVKSTTRANELTKLLN-------- 327 +Q + + N +++D +E N I+F S A LT LN Sbjct: 260 VQVPVPDMANLDNNSIWPDVEERIVDLVEAHNSSIVFANSRRLAERLTSRLNEIHAERSG 319 Query: 328 ------------------------ASNFPAITV---HGHMKQEERIARYKAFKDFEKRIC 360 A+ P + HG + +E+R K R Sbjct: 320 IELPAGPNPEVGGGAPAHLMGSGQANGAPPLLARAHHGSVSKEQRAQVEDDLKSGRLRAV 379 Query: 361 VSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAG 398 V+T GID+ ++L I + L RVGRAG Sbjct: 380 VATSSLELGIDMGAVDLVIQVEAPPSVASGLQRVGRAG 417 >6CRM-A nrPDB Length = 541 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 29/125 (23%), Positives = 57/125 (45%) Query: 285 YIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEE 344 Y+ +E+ + +L + + + II+ S + + L + A H ++ E Sbjct: 235 YMLMEKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSRGISAAAYHAGLEHEV 294 Query: 345 RIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKG 404 R + + F+ + +I V+T FG GI+ + +++D+ + Y GRAGR G Sbjct: 295 RASVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA 354 Query: 405 LAISF 409 A+ F Sbjct: 355 EAMLF 359 >5TNU-A nrPDB Length = 459 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 36/127 (28%), Positives = 60/127 (47%), Gaps = 7/127 (5%) Query: 273 EAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFP 332 EA L H + I + + K KL ++L + + ++I+F + T A ++K P Sbjct: 313 EALLAWH--ESLNIAVNSQSKIEKLREILQEYKNEKIIVFTRDTQMAYRISKTFL---IP 367 Query: 333 AITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLH 392 +T + E I + F+D E R+ V++ VF G+D+ LAI Q+L Sbjct: 368 VVTYKTDKDEREEIL--QKFRDGEYRVIVASTVFDEGVDVPDATLAIVMGGYGTKRQFLQ 425 Query: 393 RVGRAGR 399 R+GR R Sbjct: 426 RLGRILR 432 >2FWR-A nrPDB Length = 472 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 35/112 (31%), Positives = 55/112 (49%), Gaps = 7/112 (6%) Query: 286 IKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELT-KLLNASNFPAITVHGHMKQEE 344 I + K RKL ++L+ +++IIF TR NEL ++ PAIT +EE Sbjct: 329 IAFNSKNKIRKLREILERHRKDKIIIF----TRHNELVYRISKVFLIPAIT--HRTSREE 382 Query: 345 RIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGR 396 R + F+ R VS+ V GID+ N+ + + A +Y+ R+GR Sbjct: 383 REEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREYIQRLGR 434 >1OYY-A nrPDB Length = 523 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 28/125 (22%), Positives = 55/125 (44%) Query: 285 YIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEE 344 Y+ +E+ + +L + + + II+ S + + L + A H ++ Sbjct: 215 YMLMEKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNV 274 Query: 345 RIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKG 404 R + F+ + +I V+T FG GI+ + +++D+ + Y GRAGR G Sbjct: 275 RADVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA 334 Query: 405 LAISF 409 A+ F Sbjct: 335 EAMLF 339 >5LST-A nrPDB Length = 693 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 17/129 (13%) Query: 290 EREKNRKLAQLLDDLEF---NQVIIFV---KSTTR-ANELTKLLNASNFP---------- 332 +R+ ++ L LL F + +II+ + T R A L L+A+ P Sbjct: 258 DRDTDQALLTLLQGKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTT 317 Query: 333 AITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLH 392 A H M ER +AF + R+ V+T FG G+D + ++ L + Y+ Sbjct: 318 AEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQ 377 Query: 393 RVGRAGRFG 401 VGRAGR G Sbjct: 378 AVGRAGRDG 386 >2WWY-A nrPDB Length = 591 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 25/100 (25%), Positives = 47/100 (47%) Query: 310 IIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRG 369 II+ S + ++T L A H +++ E++ ++ + E ++ V+T FG G Sbjct: 271 IIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMG 330 Query: 370 IDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISF 409 ID + I++ ++ + Y GRAGR K I + Sbjct: 331 IDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILY 370 >5LB8-A nrPDB Length = 518 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 27/123 (21%), Positives = 52/123 (42%), Gaps = 7/123 (5%) Query: 310 IIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRG 369 I++ ++ +L L+ A H +K ER + + + + V+T FG G Sbjct: 255 IVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMG 314 Query: 370 IDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEV-------LAKI 422 +D + ++++ Y GRAGR G + S + ++V +AK+ Sbjct: 315 VDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKL 374 Query: 423 QER 425 QE+ Sbjct: 375 QEK 377 >5LBA-B nrPDB Length = 445 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 27/123 (21%), Positives = 52/123 (42%), Gaps = 7/123 (5%) Query: 310 IIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRG 369 I++ ++ +L L+ A H +K ER + + + + V+T FG G Sbjct: 255 IVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMG 314 Query: 370 IDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEV-------LAKI 422 +D + ++++ Y GRAGR G + S + ++V +AK+ Sbjct: 315 VDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKL 374 Query: 423 QER 425 QE+ Sbjct: 375 QEK 377 >4CDG-A nrPDB Length = 673 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 60/247 (24%), Positives = 99/247 (40%), Gaps = 38/247 (15%) Query: 178 LKNKDTAPHIVVATPGRLKALVR-----EKYIDLSHVKNFVIDECDKVLEE-LDMRRDVQ 231 L KD ++ TP ++ A R E + + FVIDE V + D R+D + Sbjct: 120 LSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYK 179 Query: 232 EI------FRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTL--HGLQQ 283 + F + P VM +AT + P ++ + L+I ++ H L+ Sbjct: 180 RMNMLRQKFPSVP----VMALTATAN----PRVQKDILTQLKILRPQVFSMSFNRHNLKY 231 Query: 284 YYIKLEEREKNRKLAQLLDDLE-------FNQVIIFVKSTTRANELTKLLNASNFPAITV 336 Y + +K +K+A D LE ++ II+ S + + L A+ Sbjct: 232 YVLP----KKPKKVA--FDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAY 285 Query: 337 HGHMKQEER--IARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRV 394 H + R + + +D + IC +T FG GID + I+ L + Y Sbjct: 286 HAGLSDSARDEVQQKWINQDGCQVIC-ATIAFGMGIDKPDVRFVIHASLPKSVEGYYQES 344 Query: 395 GRAGRFG 401 GRAGR G Sbjct: 345 GRAGRDG 351 >1GM5-A nrPDB Length = 780 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 4/87 (4%) Query: 319 ANELTKLLNASNFPAITV---HGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERI 375 A E+ + L+ FP + HG + QEE+ F + I VST V GID+ R Sbjct: 599 AVEMYEYLSKEVFPEFKLGLMHGRLSQEEKDRVMLEFAEGRYDILVSTTVIEVGIDVPRA 658 Query: 376 NLAINYDLTNEADQYLHRV-GRAGRFG 401 N+ + + LH++ GR GR G Sbjct: 659 NVMVIENPERFGLAQLHQLRGRVGRGG 685 >2FUG-6 nrPDB Length = 181 Score = 36.6 bits (83), Expect = 0.024, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 25/39 (64%) Query: 225 DMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQ 263 D+ R E+FRA+PR VM+ + LS+++ P+ RR + Sbjct: 59 DLARFGSEVFRASPRQADVMIVAGRLSKKMAPVMRRVWE 97 >5X0Y-O nrPDB Length = 735 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 5/118 (4%) Query: 307 NQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKR-IC--VST 363 ++V+IF + T + + L N + + GH K +ER + F + +C +ST Sbjct: 439 HRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILST 498 Query: 364 DVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKG--LAISFVSSKEDEEVL 419 G G++++ + I +D Q L RA R G K + +++ EEV+ Sbjct: 499 RAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVI 556 >6G19-A nrPDB Length = 696 Score = 32.7 bits (73), Expect = 0.29, Method: Compositional matrix adjust. Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 14/119 (11%) Query: 293 KNRKLAQLLDDLEFNQVIIFVKSTTRANELTK-LLNASNFPAITVHGH------------ 339 +N L Q E ++ IIF K+ L++ ++ + F + V H Sbjct: 381 RNTILEQFTRSEESSRGIIFTKTRQSTYALSQWIMENAKFAEVGVKAHHLIGAGHSSEVK 440 Query: 340 -MKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRA 397 M Q E+ F+ E + ++T V G+DI+ N+ I Y L + GRA Sbjct: 441 PMTQTEQKEVISKFRTGEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA 499 >6H8K-K nrPDB Length = 147 Score = 32.7 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 19/27 (70%) Query: 233 IFRATPRDKQVMMFSATLSQEIRPICR 259 IFRA+PR +M+ + TL+ ++ P+ R Sbjct: 48 IFRASPRQSDIMIVAGTLTNKMAPVLR 74 >4A2Q-A nrPDB Length = 797 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%) Query: 349 YKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAIS 408 +K KD R+ ++T V GIDI + NL + Y+ + + + GR G+K + ++ Sbjct: 689 FKTSKD--NRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSKCILVT 746 >4A36-A nrPDB Length = 556 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%) Query: 349 YKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAIS 408 +K KD R+ ++T V GIDI + NL + Y+ + + + GR G+K + ++ Sbjct: 448 FKTSKD--NRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSKCILVT 505 >4A2W-A nrPDB Length = 936 Score = 32.3 bits (72), Expect = 0.39, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%) Query: 349 YKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAIS 408 +K KD R+ ++T V GIDI + NL + Y+ + + + GR G+K + ++ Sbjct: 689 FKTSKD--NRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSKCILVT 746 >1WP9-A nrPDB Length = 494 Score = 32.0 bits (71), Expect = 0.52, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 29/65 (44%) Query: 352 FKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVS 411 F E + V+T V G+D+ ++L + Y+ A + + R GR GR + I Sbjct: 415 FARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSIQRRGRTGRHMPGRVIILMAK 474 Query: 412 SKEDE 416 DE Sbjct: 475 GTRDE 479 >5UMD-O nrPDB Length = 148 Score = 31.2 bits (69), Expect = 0.98, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 21/48 (43%) Query: 151 LRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKAL 198 L+ Y P + +G P K E +NKD AP I V G K L Sbjct: 64 LKNRTYCPTINVDKLWGLLPEEKKKEFSENKDIAPVIDVTRKGYFKVL 111 >4WZ7-K nrPDB Length = 183 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 20/28 (71%) Query: 233 IFRATPRDKQVMMFSATLSQEIRPICRR 260 IFRA+PR +M+ + TL+ ++ P+ R+ Sbjct: 79 IFRASPRQSDIMIVAGTLTNKMAPVLRQ 106 >4GL2-A nrPDB Length = 699 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 14/102 (13%) Query: 310 IIFVKSTTRANELTKLLNAS-NFPAITVHGH-------------MKQEERIARYKAFKDF 355 IIF K+ A L++ + + F + V H M Q E+ F+ Sbjct: 404 IIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTG 463 Query: 356 EKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRA 397 + + ++T V G+DI+ N+ I Y L + GRA Sbjct: 464 KINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA 505 >6GCS-K nrPDB Length = 210 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 20/28 (71%) Query: 233 IFRATPRDKQVMMFSATLSQEIRPICRR 260 IFRA+PR +M+ + TL+ ++ P+ R+ Sbjct: 106 IFRASPRQSDIMIVAGTLTNKMAPVLRQ 133 >6F4A-B nrPDB Length = 644 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 12/78 (15%) Query: 333 AITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGID--IERINLAIN--------YD 382 A ++G + E R+ + F E I +++D G G++ I+R+ + D Sbjct: 354 AAVIYGSLPPETRVKQANLFNSGEFDILIASDAIGMGLNLSIDRVVFTTSKKFDGRDMVD 413 Query: 383 LTNEADQYLHRVGRAGRF 400 +T+ A + + GRAGRF Sbjct: 414 MTSSAIKQIG--GRAGRF 429 >5JBJ-A nrPDB Length = 680 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 47/206 (22%), Positives = 82/206 (39%), Gaps = 34/206 (16%) Query: 259 RRFLQNPLEIFVD---DEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLE-------FNQ 308 +R ++P E F+ +E + TL L ++R +N +L++L + L+ ++ Sbjct: 319 KRDTKDPTERFLATTFEENRATLQALAG-----DQRYENPRLSKLEEILQEHFQPPGSSR 373 Query: 309 VIIFVKSTTRANELTKLLNAS--------NFPAITVHGH------MKQEERIARYKAFKD 354 I+F K+ A+ L L + +T GH M Q E+ F+ Sbjct: 374 GIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRY 433 Query: 355 FEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKE 414 E + ST V G+DI N+ + Y L + GRA + ++ +S+E Sbjct: 434 GELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANSRE 493 Query: 415 D-----EEVLAKIQERFDVKIAEFPE 435 E L + ER + PE Sbjct: 494 VYREQLNESLVGLMERAIRAVQAMPE 519 >2NMV-A nrPDB Length = 661 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 37/156 (23%), Positives = 60/156 (38%), Gaps = 27/156 (17%) Query: 304 LEFNQVIIFVKSTTRANE-LTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 362 +E N+ ++ T + +E LT L +H +K ERI + + + + V Sbjct: 442 IERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIKTLERIEIIRDLRLGKYDVLVG 501 Query: 363 TDVFGRGIDIERINLAINYDLTNEA-----DQYLHRVGRAGRFG-----------TKGLA 406 ++ G+DI ++L D E + +GRA R TK + Sbjct: 502 INLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITKSME 561 Query: 407 ISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPST 442 I+ +K E QERF+ E GI P T Sbjct: 562 IAINETKRRREQ----QERFN------EEHGITPKT 587 >6G72-B nrPDB Length = 224 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 19/28 (67%) Query: 233 IFRATPRDKQVMMFSATLSQEIRPICRR 260 +FRA+PR VM+ + TL+ ++ P R+ Sbjct: 120 VFRASPRQADVMIVAGTLTNKMAPALRK 147 >5GPN-a nrPDB Length = 216 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 19/28 (67%) Query: 233 IFRATPRDKQVMMFSATLSQEIRPICRR 260 +FRA+PR VM+ + TL+ ++ P R+ Sbjct: 112 VFRASPRQSDVMIVAGTLTNKMAPALRK 139 >5O31-B nrPDB Length = 179 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 19/28 (67%) Query: 233 IFRATPRDKQVMMFSATLSQEIRPICRR 260 +FRA+PR VM+ + TL+ ++ P R+ Sbjct: 75 VFRASPRQSDVMIVAGTLTNKMAPALRK 102 >4BPB-A nrPDB Length = 698 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 24/50 (48%) Query: 359 ICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAIS 408 I ++T V GIDI + NL I Y+ + + GR G+K ++ Sbjct: 466 ILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLT 515 >5XTD-C nrPDB Length = 156 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 19/28 (67%) Query: 233 IFRATPRDKQVMMFSATLSQEIRPICRR 260 +FRA+PR VM+ + TL+ ++ P R+ Sbjct: 52 VFRASPRQSDVMIVAGTLTNKMAPALRK 79 >5HZR-A nrPDB Length = 732 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 32/129 (24%), Positives = 53/129 (41%), Gaps = 8/129 (6%) Query: 307 NQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK---RICVST 363 ++V++F + T + + L + + G K E+R + F + +ST Sbjct: 446 HRVLMFFQMTAIMDIMEDFLRFRGLHYLRLDGTTKSEDRSELLRQFNQPDSPYFMFLLST 505 Query: 364 DVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLA--ISFVSSKEDEEVLAK 421 G G++++ + I YD Q L RA R G K + +SS EE K Sbjct: 506 RAGGLGLNLQTADTVIIYDSDWNPHQDLQAQDRAHRIGQKNEVRILRLISSASVEE---K 562 Query: 422 IQERFDVKI 430 I ER K+ Sbjct: 563 ILERARFKL 571 >3DIN-A nrPDB Length = 871 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 22/144 (15%) Query: 282 QQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFP--AITVHGH 339 ++Y +EE EK K Q V++ S ++ L+ +L P + H Sbjct: 458 EKYEKIVEEIEKRYKKGQ--------PVLVGTTSIEKSELLSSMLKKKGIPHQVLNAKYH 509 Query: 340 MKQEERIARYKAFKDFEKRICVSTDVFGRGIDI-------ERINLAINYDLTNEADQYLH 392 K+ E +A+ + + ++T++ GRG DI E L I +E+ + + Sbjct: 510 EKEAEIVAKAGQ----KGMVTIATNMAGRGTDIKLGPGVAELGGLCIIGTERHESRRIDN 565 Query: 393 RV-GRAGRFGTKGLAISFVSSKED 415 ++ GRAGR G G +I F+S ++D Sbjct: 566 QLRGRAGRQGDPGESIFFLSLEDD 589 >4ON9-A nrPDB Length = 580 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 24/50 (48%) Query: 359 ICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAIS 408 I ++T V GIDI + NL I Y+ + + GR G+K ++ Sbjct: 480 ILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLT 529 >2XYJ-A nrPDB Length = 288 Score = 28.5 bits (62), Expect = 5.9, Method: Compositional matrix adjust. Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 13/117 (11%) Query: 46 NTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQ 105 N D K I++ K+F + + +R+I+ + HT P IH + L Q Sbjct: 16 NPQVADLKAFSKHIYNAYLKNFNMTKKKARSIL-------TGKASHTAPFVIHDIETLWQ 68 Query: 106 AKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKT 162 A+ GL V L P E++V V + + E F+K +P + Sbjct: 69 AEKGL------VWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSS 119 >5JCF-A nrPDB Length = 701 Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust. Identities = 43/174 (24%), Positives = 66/174 (37%), Gaps = 23/174 (13%) Query: 294 NRKLAQLLDDL--EFNQV-----IIFVKSTTRANELTK-LLNASNFPAITVHGH------ 339 N KL +L + L EF + IIF K+ A L +++ F + + H Sbjct: 380 NEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAG 439 Query: 340 -------MKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLH 392 M Q E+ F+ + ++T V G+DI+ N+ I Y L + Sbjct: 440 HNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQ 499 Query: 393 RVGRA-GRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYLN 445 GRA T L S S + E + +E K +E + P YLN Sbjct: 500 ARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQE-MPPEEYLN 552 >1D9Z-A nrPDB Length = 657 Score = 28.1 bits (61), Expect = 7.5, Method: Compositional matrix adjust. Identities = 23/109 (21%), Positives = 46/109 (42%), Gaps = 6/109 (5%) Query: 297 LAQLLDDLEFNQVIIFVKSTTR-ANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDF 355 + ++ + +E N+ + T + A +LT L + +H +K ERI + + Sbjct: 434 IGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLG 493 Query: 356 EKRICVSTDVFGRGIDIERINLAINYDLTNEA-----DQYLHRVGRAGR 399 + + V ++ G+DI ++L D E + +GRA R Sbjct: 494 KYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAAR 542 >3G25-A nrPDB Length = 501 Score = 27.7 bits (60), Expect = 9.9, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 19/29 (65%) Query: 404 GLAISFVSSKEDEEVLAKIQERFDVKIAE 432 GLA+ F SK+D K++E+FD K+ E Sbjct: 450 GLAVGFWESKDDIAKNWKLEEKFDPKMDE 478 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5SUQ-A nrPDB 655 0.0 5SUP-A nrPDB 546 e-155 1XTI-A nrPDB 516 e-147 4BRW-A nrPDB 472 e-134 5ANR-B nrPDB 466 e-132 6B4I-E nrPDB 465 e-131 2HYI-C nrPDB 465 e-131 3EIQ-A nrPDB 442 e-124 5IVL-B nrPDB 440 e-124 4NHO-A nrPDB 432 e-121 2VSX-A nrPDB 430 e-121 4D25-A nrPDB 429 e-120 3PEW-A nrPDB 427 e-120 3JCR-F nrPDB 422 e-118 2DB3-A nrPDB 418 e-117 1HV8-A nrPDB 418 e-117 6CZ5-A nrPDB 417 e-117 2I4I-A nrPDB 417 e-117 5DTU-A nrPDB 417 e-117 3FHO-A nrPDB 382 e-106 6CB1-p nrPDB 381 e-106 4KBG-A nrPDB 378 e-105 4W7S-A nrPDB 373 e-104 5ZWN-y nrPDB 373 e-103 4LJY-A nrPDB 358 4e-99 2Z0M-A nrPDB 356 7e-99 3SQW-A nrPDB 326 9e-90 3I62-A nrPDB 325 3e-89 1T6N-A nrPDB 311 3e-85 5ZBZ-A nrPDB 279 2e-75 3BOR-A nrPDB 278 5e-75 3FHC-B nrPDB 277 6e-75 3FMO-B nrPDB 276 2e-74 5GJU-A nrPDB 271 3e-73 4Q48-A nrPDB 264 4e-71 1QVA-A nrPDB 263 9e-71 1WRB-A nrPDB 261 4e-70 1VEC-A nrPDB 261 6e-70 2GXQ-A nrPDB 256 2e-68 4PX9-A nrPDB 254 8e-68 5H1Y-A nrPDB 248 3e-66 2OXC-A nrPDB 247 7e-66 3FE2-A nrPDB 247 9e-66 2KBE-A nrPDB 243 9e-65 1Q0U-A nrPDB 242 2e-64 5GVS-A nrPDB 241 3e-64 3IUY-A nrPDB 241 4e-64 6CRM-A nrPDB 240 1e-63 6AIC-A nrPDB 240 1e-63 3BER-A nrPDB 236 1e-62 1OYY-A nrPDB 232 2e-61 5V9X-A nrPDB 225 3e-59 2PL3-A nrPDB 224 5e-59 3DKP-A nrPDB 215 3e-56 3LY5-A nrPDB 207 1e-53 5LBA-B nrPDB 205 4e-53 5LB8-A nrPDB 205 4e-53 5LST-A nrPDB 192 2e-49 2WWY-A nrPDB 189 2e-48 5TNU-A nrPDB 116 1e-26 2FWR-A nrPDB 111 5e-25 Sequences not found previously or not previously below threshold: 4CDG-A nrPDB 190 1e-48 2P6R-A nrPDB 121 8e-28 2ZJ8-A nrPDB 120 1e-27 2VA8-A nrPDB 118 4e-27 1GM5-A nrPDB 103 2e-22 5AGA-A nrPDB 96 2e-20 1WP9-A nrPDB 95 7e-20 6C90-A nrPDB 88 5e-18 3P4X-A nrPDB 83 3e-16 2NMV-A nrPDB 79 4e-15 1D9Z-A nrPDB 79 4e-15 1C4O-A nrPDB 73 2e-13 4XGT-A nrPDB 72 6e-13 4GL2-A nrPDB 68 6e-12 5JBJ-A nrPDB 68 7e-12 6G19-A nrPDB 68 9e-12 5VHD-D nrPDB 68 1e-11 5JCF-A nrPDB 64 9e-11 3TBK-A nrPDB 64 1e-10 5GM6-Y nrPDB 63 3e-10 4ON9-A nrPDB 62 5e-10 4BPB-A nrPDB 62 7e-10 6ID1-V nrPDB 62 7e-10 5N8S-A nrPDB 61 1e-09 6BOG-A nrPDB 60 2e-09 5I8Q-A nrPDB 60 2e-09 6FA9-A nrPDB 60 3e-09 6HEG-A nrPDB 60 3e-09 5D0U-A nrPDB 59 3e-09 4A2W-A nrPDB 59 4e-09 4A2Q-A nrPDB 59 5e-09 3DIN-A nrPDB 59 5e-09 5XDR-A nrPDB 58 5e-09 5FMF-1 nrPDB 58 6e-09 4A36-A nrPDB 58 7e-09 5SVA-Z nrPDB 58 9e-09 6F4A-B nrPDB 57 1e-08 6DCR-A nrPDB 56 3e-08 6I3O-A nrPDB 56 4e-08 6FTX-W nrPDB 55 6e-08 5WSO-A nrPDB 55 7e-08 4CBI-A nrPDB 55 7e-08 4NL8-A nrPDB 55 9e-08 5WX1-A nrPDB 55 9e-08 3RC8-A nrPDB 54 1e-07 6NMI-A nrPDB 54 1e-07 5OF4-A nrPDB 54 1e-07 5IY9-V nrPDB 54 1e-07 5OQJ-7 nrPDB 54 1e-07 4A4Z-A nrPDB 54 1e-07 5WDX-A nrPDB 53 2e-07 4UAQ-A nrPDB 53 3e-07 4B6E-A nrPDB 53 3e-07 2ZJO-A nrPDB 52 4e-07 4OK6-A nrPDB 52 4e-07 3B6E-A nrPDB 52 5e-07 3MWY-W nrPDB 52 7e-07 5X0Y-O nrPDB 50 3e-06 5HZR-A nrPDB 48 7e-06 4ERN-A nrPDB 48 7e-06 2OCA-A nrPDB 47 2e-05 2V6J-A nrPDB 47 2e-05 5K8T-A nrPDB 46 3e-05 5JXT-B nrPDB 45 6e-05 5JXR-A nrPDB 45 6e-05 2BMF-A nrPDB 45 9e-05 2QEQ-A nrPDB 44 2e-04 5GN1-A nrPDB 44 2e-04 2WV9-A nrPDB 43 2e-04 2V8O-A nrPDB 43 2e-04 3BXZ-A nrPDB 43 3e-04 1TF2-A nrPDB 43 3e-04 5EUL-A nrPDB 43 4e-04 3H1T-A nrPDB 43 4e-04 1Z6A-A nrPDB 41 8e-04 2JLW-A nrPDB 41 0.001 1Z5Z-A nrPDB 41 0.001 2WZQ-A nrPDB 41 0.001 1NLZ-A nrPDB 39 0.004 1NL3-A nrPDB 38 0.007 6FWS-A nrPDB 38 0.011 1Z3I-X nrPDB 35 0.062 3LLM-A nrPDB 34 0.11 2V1U-A nrPDB 33 0.18 2EBD-A nrPDB 33 0.23 4M44-A nrPDB 33 0.31 1RRL-A nrPDB 33 0.38 3A2B-A nrPDB 32 0.63 6EG3-A nrPDB 32 0.64 3ACB-A nrPDB 31 0.78 5K9T-A nrPDB 31 0.89 6J5T-G nrPDB 31 0.97 5H8W-A nrPDB 31 1.1 5B55-A nrPDB 31 1.2 2FSI-A nrPDB 31 1.2 6EJ5-A nrPDB 31 1.3 2WJV-A nrPDB 31 1.3 4HZU-A nrPDB 31 1.3 1UB3-A nrPDB 31 1.4 1SXJ-C nrPDB 30 1.7 3FCY-A nrPDB 30 1.7 3AHX-A nrPDB 30 1.9 2B8N-A nrPDB 30 2.0 3T0T-A nrPDB 30 3.1 1WA5-C nrPDB 29 3.4 1YID-B nrPDB 29 3.4 2AOV-A nrPDB 29 3.9 4XRF-A nrPDB 29 4.1 3L76-A nrPDB 28 5.9 5OPT-P nrPDB 28 8.5 >5SUQ-A nrPDB Length = 446 Score = 655 bits (1689), Expect = 0.0, Method: Composition-based stats. Identities = 446/446 (100%), Positives = 446/446 (100%) Query: 1 MSHEGEEDLLEYSDNEQEIQIDASKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIH 60 MSHEGEEDLLEYSDNEQEIQIDASKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIH Sbjct: 1 MSHEGEEDLLEYSDNEQEIQIDASKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIH 60 Query: 61 STGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLST 120 STGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLST Sbjct: 61 STGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLST 120 Query: 121 LQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKN 180 LQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKN Sbjct: 121 LQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKN 180 Query: 181 KDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRD 240 KDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRD Sbjct: 181 KDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRD 240 Query: 241 KQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQL 300 KQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQL Sbjct: 241 KQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQL 300 Query: 301 LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRIC 360 LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRIC Sbjct: 301 LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRIC 360 Query: 361 VSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLA 420 VSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLA Sbjct: 361 VSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLA 420 Query: 421 KIQERFDVKIAEFPEEGIDPSTYLNN 446 KIQERFDVKIAEFPEEGIDPSTYLNN Sbjct: 421 KIQERFDVKIAEFPEEGIDPSTYLNN 446 >5SUP-A nrPDB Length = 390 Score = 546 bits (1406), Expect = e-155, Method: Composition-based stats. Identities = 386/389 (99%), Positives = 387/389 (99%) Query: 58 GIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFV 117 + STGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFV Sbjct: 2 AMGSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFV 61 Query: 118 LSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL 177 LSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL Sbjct: 62 LSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL 121 Query: 178 LKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRAT 237 LKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRAT Sbjct: 122 LKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRAT 181 Query: 238 PRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKL 297 PRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKL Sbjct: 182 PRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKL 241 Query: 298 AQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK 357 AQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK Sbjct: 242 AQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK 301 Query: 358 RICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEE 417 RICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEE Sbjct: 302 RICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEE 361 Query: 418 VLAKIQERFDVKIAEFPEEGIDPSTYLNN 446 VLAKIQERFDVKIAEFPEEGIDPSTYLNN Sbjct: 362 VLAKIQERFDVKIAEFPEEGIDPSTYLNN 390 >1XTI-A nrPDB Length = 391 Score = 516 bits (1330), Expect = e-147, Method: Composition-based stats. Identities = 259/390 (66%), Positives = 322/390 (82%), Gaps = 3/390 (0%) Query: 55 SYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTA 114 G S+GF+DFLLKPEL RAI+DCGFEHPSEVQ IPQ+I G DVLCQAKSG+GKTA Sbjct: 1 GSPGHMSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTA 60 Query: 115 VFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKD 174 VFVL+TLQQL+PV G+V+V+V+C+ RELA+QI EY RFSKYMP+VK AVF+GG I KD Sbjct: 61 VFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKD 120 Query: 175 AELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIF 234 E+LK PHIVV TPGR+ AL R K ++L H+K+F++DECDK+LE+LDMRRDVQEIF Sbjct: 121 EEVLKKN--CPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIF 178 Query: 235 RATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKN 294 R TP +KQVMMFSATLS+EIRP+CR+F+Q+P+EIFVDDE KLTLHGLQQYY+KL++ EKN Sbjct: 179 RMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKN 238 Query: 295 RKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKD 354 RKL LLD LEFNQV+IFVKS R L +LL NFPAI +H M QEER++RY+ FKD Sbjct: 239 RKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKD 298 Query: 355 FEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKE 414 F++RI V+T++FGRG+DIER+N+A NYD+ ++D YLHRV RAGRFGTKGLAI+FVS + Sbjct: 299 FQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEN 358 Query: 415 DEEVLAKIQERFDVKIAEFPEEGIDPSTYL 444 D ++L +Q+RF+V I+E P+E ID S+Y+ Sbjct: 359 DAKILNDVQDRFEVNISELPDE-IDISSYI 387 >4BRW-A nrPDB Length = 377 Score = 472 bits (1216), Expect = e-134, Method: Composition-based stats. Identities = 143/382 (37%), Positives = 206/382 (53%), Gaps = 9/382 (2%) Query: 63 GFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQ 122 F+DF LK EL I + GFE PS +Q+ IP +I G D+L +AK+G GKTA FV+ TL+ Sbjct: 2 TFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTLE 61 Query: 123 QLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKD 182 ++ P ++ +++ RELA Q K+ + V GGT + D L + Sbjct: 62 KVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHC-GISCMVTTGGTNLRDDILRL---N 117 Query: 183 TAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQ 242 HI+V TPGR+ L K DLS F++DE DK+L D + +++I P Q Sbjct: 118 ETVHILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSR-DFKTIIEQILSFLPPTHQ 176 Query: 243 VMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLD 302 ++FSAT + + L P EI + + +LTL G+ QYY +EER+K L L Sbjct: 177 SLLFSATFPLTVDEFMDKHLHKPYEINLME--ELTLKGITQYYAFVEERQKLHCLNTLFS 234 Query: 303 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 362 L+ NQ IIF ST R L K + + H MKQ+ER + F+ + R V Sbjct: 235 KLQINQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRTLVC 294 Query: 363 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 422 +D+ RGIDI+ +N+ IN+D A+ YLHR+GR+GRFG GLAI+ ++ D L KI Sbjct: 295 SDLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINW-NDRFNLYKI 353 Query: 423 QERFDVKIAEFPEEGIDPSTYL 444 ++ +IA P ID S Y+ Sbjct: 354 EQELGTEIAAIPAT-IDKSLYV 374 >5ANR-B nrPDB Length = 378 Score = 466 bits (1199), Expect = e-132, Method: Composition-based stats. Identities = 136/380 (35%), Positives = 217/380 (57%), Gaps = 8/380 (2%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F+D+ LK EL I + G+E PS +Q+ +IP ++ G D+L +AK+G GK+ +++ L++ Sbjct: 7 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 66 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 LD + +VI RELA Q+ ++ SK+M K GGT + D + D Sbjct: 67 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDD---IMRLDD 123 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 H+V+ATPGR+ L+++ + HV+ V+DE DK+L + D + +++I P+++Q+ Sbjct: 124 TVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMEDIILTLPKNRQI 182 Query: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDD 303 +++SAT ++ LQ P EI + + +LTL G+ QYY + ER+K L L Sbjct: 183 LLYSATFPLSVQKFMNSHLQKPYEINLME--ELTLKGVTQYYAYVTERQKVHCLNTLFSR 240 Query: 304 LEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVST 363 L+ NQ IIF S+ R L K ++ + +H M+QE R + F++ R V T Sbjct: 241 LQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCT 300 Query: 364 DVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQ 423 D+F RGIDI+ +N+ IN+D A+ YLHR+GR+GRFG GLAI+ ++ +D L I+ Sbjct: 301 DLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITY-DDRFNLKSIE 359 Query: 424 ERFDVKIAEFPEEGIDPSTY 443 E+ +I P ID S Y Sbjct: 360 EQLGTEIKPIPSN-IDKSLY 378 >6B4I-E nrPDB Length = 430 Score = 465 bits (1198), Expect = e-131, Method: Composition-based stats. Identities = 122/415 (29%), Positives = 211/415 (50%), Gaps = 17/415 (4%) Query: 42 DNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIH--G 99 DN N + + F++ LKP+L + + GF PS++Q++ +P + Sbjct: 23 DNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPP 82 Query: 100 TDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPD 159 +++ Q++SG GKTA FVL+ L Q++P + + ELA Q + K+ P+ Sbjct: 83 QNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPE 142 Query: 160 VKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKA-LVREKYIDLSHVKNFVIDECD 218 +K A G +L + + + IV+ TPG + + K+ID +K FV+DE D Sbjct: 143 LKLAYAVRGN------KLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 196 Query: 219 KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTL 278 ++ + I R PR+ Q+++FSAT + ++ + +P I + E + TL Sbjct: 197 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE-TL 255 Query: 279 HGLQQYYIKLEER-EKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVH 337 ++QYY+ R EK + L L + Q +IF + A+ L L+ + Sbjct: 256 DTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLS 315 Query: 338 GHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLT------NEADQYL 391 G M E+R A + F++ ++++ V+T+V RGID+E++++ IN+DL + + YL Sbjct: 316 GEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYL 375 Query: 392 HRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYLNN 446 HR+GR GRFG +GLA++ V SK +L +IQE F+ KI + +D + N Sbjct: 376 HRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 430 >2HYI-C nrPDB Length = 413 Score = 465 bits (1196), Expect = e-131, Method: Composition-based stats. Identities = 137/378 (36%), Positives = 218/378 (57%), Gaps = 8/378 (2%) Query: 63 GFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQ 122 F L+ +L R I GFE PS +QQ I Q I G DV+ Q++SG GKTA F +S LQ Sbjct: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 Query: 123 QLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKD 182 LD E +++ RELA QI+ L YM +V+ GGT + +D ++ D Sbjct: 99 CLDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGED---IRKLD 154 Query: 183 TAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQ 242 H+V TPGR+ ++R + + +K V+DE D++L + + + +++R P Q Sbjct: 155 YGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQ 213 Query: 243 VMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLE-EREKNRKLAQLL 301 V++ SATL EI + +F+ +P+ I V + +LTL G++Q+++ +E E K L L Sbjct: 214 VVLISATLPHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLY 272 Query: 302 DDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICV 361 D L Q +IF + + + LT+ + +NF ++HG M Q+ER + K F+ R+ + Sbjct: 273 DTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLI 332 Query: 362 STDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAK 421 STDV+ RG+D+ +++L INYDL N + Y+HR+GR+GR+G KG+AI+FV +D +L Sbjct: 333 STDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV-KNDDIRILRD 391 Query: 422 IQERFDVKIAEFPEEGID 439 I++ + +I E P D Sbjct: 392 IEQYYSTQIDEMPMNVAD 409 >3EIQ-A nrPDB Length = 414 Score = 442 bits (1136), Expect = e-124, Method: Composition-based stats. Identities = 137/378 (36%), Positives = 217/378 (57%), Gaps = 7/378 (1%) Query: 63 GFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQ 122 F D L L R I GFE PS +QQ I I G DV+ QA+SG GKTA F +S LQ Sbjct: 41 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 100 Query: 123 QLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKD 182 Q++ +V+ RELA QI+ + YM GGT + AE+ K + Sbjct: 101 QIELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVR--AEVQKLQM 157 Query: 183 TAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQ 242 APHI+V TPGR+ ++ +Y+ ++K FV+DE D++L + + +IF+ + Q Sbjct: 158 EAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQ 216 Query: 243 VMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLE-EREKNRKLAQLL 301 V++ SAT+ ++ + ++F+++P+ I V E +LTL G++Q+YI +E E K L L Sbjct: 217 VVLLSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVEREEWKLDTLCDLY 275 Query: 302 DDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICV 361 + L Q +IF+ + + + LT+ ++A +F +HG M Q+ER + F+ R+ + Sbjct: 276 ETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLI 335 Query: 362 STDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAK 421 +TD+ RGID+++++L INYDL + Y+HR+GR GRFG KG+AI+ V+ +ED+ L Sbjct: 336 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVT-EEDKRTLRD 394 Query: 422 IQERFDVKIAEFPEEGID 439 I+ ++ I E P D Sbjct: 395 IETFYNTSIEEMPLNVAD 412 >5IVL-B nrPDB Length = 429 Score = 440 bits (1132), Expect = e-124, Method: Composition-based stats. Identities = 123/381 (32%), Positives = 205/381 (53%), Gaps = 7/381 (1%) Query: 62 TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 T F++ L E+ +AI GFE + +Q TIP S+ DV+ QA++G GKTA F + + Sbjct: 2 TTFQELGLSQEVMKAIERMGFEETTPIQAKTIPLSLQNKDVIGQAQTGTGKTAAFGIPIV 61 Query: 122 QQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNK 181 +++D G + +V+ RELA Q+ E + + V+ YGG I + LK Sbjct: 62 EKVDVKNGAIQALVVAPTRELAIQVSEELYKIGA-VKRVRVLPIYGGQDIERQIRALKKH 120 Query: 182 DTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDK 241 PH++V TPGR+ + + L HV V+DE D++L + D++ I P ++ Sbjct: 121 ---PHVIVGTPGRIIDHINRGTLRLEHVHTVVLDEADEMLN-MGFIEDIEAILSHVPAER 176 Query: 242 QVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLL 301 Q ++FSAT+ IR I RF+ P + V ++T+ +QQYY+++ E++K L +LL Sbjct: 177 QTLLFSATMPDPIRRIAERFMNEPELVKV-KAKEMTVPNIQQYYLEVHEKKKFDILTRLL 235 Query: 302 DDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICV 361 D I+F ++ R +EL + LN + A +HG + Q +R++ + FK+ I V Sbjct: 236 DIQAPELAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLSQAKRLSVLRKFKEGAIEILV 295 Query: 362 STDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAK 421 +TDV RG+DI + N+D+ + + Y+HR+GR GR G G+A++FV+ +E L Sbjct: 296 ATDVAARGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGKTGVAMTFVTPRE-IGQLHH 354 Query: 422 IQERFDVKIAEFPEEGIDPST 442 I+ K+ +D + Sbjct: 355 IERTTKRKMERMKPPTLDEAL 375 >4NHO-A nrPDB Length = 488 Score = 432 bits (1112), Expect = e-121, Method: Composition-based stats. Identities = 120/420 (28%), Positives = 202/420 (48%), Gaps = 43/420 (10%) Query: 53 KGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGK 112 KG + +KD L P + I CG++ P+ +Q+ IP + D++ A++G GK Sbjct: 50 KGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGK 109 Query: 113 TAVFVLSTLQQLDPVPG---------EVAVVVICNARELAYQIRNEYLRFSKYMPDVKTA 163 TA F++ L + +P +++ RELA QI E ++F K + ++T Sbjct: 110 TAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPL-GIRTV 168 Query: 164 VFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEE 223 GG L+ IV+ATPGRL ++ +Y+ LS V+DE D++++ Sbjct: 169 AVIGGISREDQGFRLR---MGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMID- 224 Query: 224 LDMRRDVQEIFRATP--------------------------RDKQVMMFSATLSQEIRPI 257 + DVQ+I P + +Q +MF+AT+ + + Sbjct: 225 MGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERL 284 Query: 258 CRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTT 317 R +L+ P +++ K ++Q + E EK +KL +L+ +IIFV Sbjct: 285 ARSYLRRPAVVYIGSAGKPHER-VEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKK 343 Query: 318 RANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINL 377 + L K L + A T+HG QE+R K K I V+TDV GRGIDI+ +++ Sbjct: 344 GCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSM 403 Query: 378 AINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQER-FDVKIAEFPEE 436 +NYD+ + Y+HR+GR GR G G+AI+F++ KED V ++++ + ++ P E Sbjct: 404 VVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLT-KEDSAVFYELKQAILESPVSSCPPE 462 >2VSX-A nrPDB Length = 395 Score = 430 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 137/401 (34%), Positives = 218/401 (54%), Gaps = 13/401 (3%) Query: 46 NTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQ 105 + + +Y + F D L L R + GFE PS +QQ I I G DVL Q Sbjct: 7 DIEESQIQTNYDKVVYK-FDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQ 65 Query: 106 AKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVF 165 A+SG GKT F ++ LQ++D +++ RELA QI+ + + +M D+K Sbjct: 66 AQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHM-DIKVHAC 124 Query: 166 YGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELD 225 GGT +DAE L++ IVV TPGR+ ++ + +K F++DE D++L Sbjct: 125 IGGTSFVEDAEGLRD----AQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSS-G 179 Query: 226 MRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYY 285 + + +IF P QV++ SAT+ ++ + +F++NP+ I V + +LTL G++Q+Y Sbjct: 180 FKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKD-ELTLEGIKQFY 238 Query: 286 IKLEERE-KNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEE 344 + +EE E K L L D + Q +IF + + ELT L F ++ + Q+E Sbjct: 239 VNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQE 298 Query: 345 RIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKG 404 R K F+ RI +STD+ RGID+++++L INYDL + Y+HR+GR GRFG KG Sbjct: 299 RDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKG 358 Query: 405 LAISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYLN 445 +AI+FV+ ED + ++++ + +I E P D +T LN Sbjct: 359 VAINFVT-NEDVGAMRELEKFYSTQIEELPS---DIATLLN 395 >4D25-A nrPDB Length = 434 Score = 429 bits (1104), Expect = e-120, Method: Composition-based stats. Identities = 114/400 (28%), Positives = 202/400 (50%), Gaps = 19/400 (4%) Query: 49 AGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKS 108 A G F+ L+ + ++ G+ P+ +Q++ IP + G D++ A++ Sbjct: 37 AVKVSGENPPRPIESFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQT 96 Query: 109 GLGKTAVFVLSTLQQLDPVPG---------EVAVVVICNARELAYQIRNEYLRFSKYMPD 159 G GKTA F++ + L P + V+++ REL QI NE +FS Y Sbjct: 97 GSGKTAAFLVPIINMLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNEARKFS-YGSV 155 Query: 160 VKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDK 219 +K AV YGGT + + N HI+VATPGRL V + V+ V+D+ D Sbjct: 156 LKVAVAYGGTAVRHQGD---NIARGCHILVATPGRLHDFVERNRVSFGSVRFVVLDQADC 212 Query: 220 VLEELDMRRDVQEIFRATP----RDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAK 275 +L+ + ++++ +Q +MFSAT ++I+ + RFL N L + V Sbjct: 213 MLD-MGFMPSIEKMMLHPTMVETTKRQTLMFSATFPEDIQHLAGRFLNNYLFVAVGIVGG 271 Query: 276 LTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAIT 335 + ++Q +I++ + EK L QL+++ + ++++FV++ A+ + +L+ + Sbjct: 272 ASTD-VEQIFIEVTKYEKRNSLKQLIEENDGKRILVFVETKRNADFIAAMLSEQQLLTSS 330 Query: 336 VHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVG 395 +HG Q ER + FK + I V+T V RG+DI+ +++ +NYDL D+Y+HR+G Sbjct: 331 IHGDRMQREREEALQNFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIG 390 Query: 396 RAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPE 435 R GR G +G A+SF S +D ++A + + P+ Sbjct: 391 RTGRVGNRGKAVSFYDSDQDLALVADLSKILRQADQSVPD 430 >3PEW-A nrPDB Length = 395 Score = 427 bits (1097), Expect = e-120, Method: Composition-based stats. Identities = 114/392 (29%), Positives = 197/392 (50%), Gaps = 19/392 (4%) Query: 58 GIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHG--TDVLCQAKSGLGKTAV 115 G + F + L PEL + I F+ PS++Q+ +P +H +++ Q++SG GKTA Sbjct: 1 GAMAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAA 60 Query: 116 FVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDA 175 F L+ L +++P + + +RELA Q K+ I D+ Sbjct: 61 FSLTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTK-------ITSQLIVPDS 113 Query: 176 ELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFR 235 KNK ++V TPG + L+R K + L +K FV+DE D +L++ + + R Sbjct: 114 -FEKNKQINAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKR 172 Query: 236 ATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKL-EEREKN 294 P+D Q+++FSAT + +R ++ + N + + ++ + ++Q Y+ E +K Sbjct: 173 FLPKDTQLVLFSATFADAVRQYAKKIVPNANTLELQT-NEVNVDAIKQLYMDCKNEADKF 231 Query: 295 RKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKD 354 L +L + IIFV + AN L L + +HG ++ +ER F++ Sbjct: 232 DVLTELYGVMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFRE 291 Query: 355 FEKRICVSTDVFGRGIDIERINLAINYDLTN------EADQYLHRVGRAGRFGTKGLAIS 408 ++ ++T+V RGIDI +++ +NYDL + Y+HR+GR GRFG KG+AIS Sbjct: 292 GRSKVLITTNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAIS 351 Query: 409 FVSSKEDEEVLAKIQERF-DVKIAEFPEEGID 439 FV K +L+ IQ+ F D+++ P + D Sbjct: 352 FVHDKNSFNILSAIQKYFGDIEMTRVPTDDWD 383 >3JCR-F nrPDB Length = 820 Score = 422 bits (1084), Expect = e-118, Method: Composition-based stats. Identities = 120/420 (28%), Positives = 202/420 (48%), Gaps = 43/420 (10%) Query: 53 KGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGK 112 KG + +KD L P + I CG++ P+ +Q+ IP + D++ A++G GK Sbjct: 382 KGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGK 441 Query: 113 TAVFVLSTLQQLDPVPG---------EVAVVVICNARELAYQIRNEYLRFSKYMPDVKTA 163 TA F++ L + +P +++ RELA QI E ++F K + ++T Sbjct: 442 TAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPL-GIRTV 500 Query: 164 VFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEE 223 GG L+ IV+ATPGRL ++ +Y+ LS V+DE D++++ Sbjct: 501 AVIGGISREDQGFRLR---MGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMID- 556 Query: 224 LDMRRDVQEIFRATP--------------------------RDKQVMMFSATLSQEIRPI 257 + DVQ+I P + +Q +MF+AT+ + + Sbjct: 557 MGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERL 616 Query: 258 CRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTT 317 R +L+ P +++ K ++Q + E EK +KL +L+ +IIFV Sbjct: 617 ARSYLRRPAVVYIGSAGKPHER-VEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKK 675 Query: 318 RANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINL 377 + L K L + A T+HG QE+R K K I V+TDV GRGIDI+ +++ Sbjct: 676 GCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSM 735 Query: 378 AINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQER-FDVKIAEFPEE 436 +NYD+ + Y+HR+GR GR G G+AI+F++ KED V ++++ + ++ P E Sbjct: 736 VVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLT-KEDSAVFYELKQAILESPVSSCPPE 794 >2DB3-A nrPDB Length = 434 Score = 418 bits (1076), Expect = e-117, Method: Composition-based stats. Identities = 123/420 (29%), Positives = 205/420 (48%), Gaps = 16/420 (3%) Query: 23 ASKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGF 82 ++ A E +G A S NN GS V F L+ + + G+ Sbjct: 19 SNDAIEIFSSGIA-SGIHFSKYNNIPV-KVTGSDVPQPIQHFTSADLRDIIIDNVNKSGY 76 Query: 83 EHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVP-----GEVAVVVIC 137 + P+ +Q+ +IP G D++ A++G GKTA F+L L +L P G VV++ Sbjct: 77 KIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHELELGRPQVVIVS 136 Query: 138 NARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKA 197 RELA QI NE +F+ + +K + YGGT E + H+V+ATPGRL Sbjct: 137 PTRELAIQIFNEARKFA-FESYLKIGIVYGGTSFRHQNECI---TRGCHVVIATPGRLLD 192 Query: 198 LVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRA--TPRDKQVMMFSATLSQEIR 255 V +I + V+DE D++L+ + D++ I + Q +MFSAT +EI+ Sbjct: 193 FVDRTFITFEDTRFVVLDEADRMLD-MGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQ 251 Query: 256 PICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKS 315 + FL+N + + + Q Y ++ + K KL ++L + + + I+FV++ Sbjct: 252 RMAGEFLKNYVFVAIGIVGGACSDVKQTIY-EVNKYAKRSKLIEILSE-QADGTIVFVET 309 Query: 316 TTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERI 375 A+ L L+ FP ++HG Q +R + FK+ ++ ++T V RG+DI+ I Sbjct: 310 KRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNI 369 Query: 376 NLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPE 435 INYD+ ++ D Y+HR+GR GR G G A SF ++D + A + + + P+ Sbjct: 370 KHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAADLVKILEGSGQTVPD 429 >1HV8-A nrPDB Length = 367 Score = 418 bits (1076), Expect = e-117, Method: Composition-based stats. Identities = 119/376 (31%), Positives = 206/376 (54%), Gaps = 15/376 (3%) Query: 59 IHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGT-DVLCQAKSGLGKTAVFV 117 + F + L + AI + GFE P+++Q IP ++ +++ QA++G GKTA F Sbjct: 3 VEYMNFNELNLSDNILNAIRNKGFEKPTDIQMKVIPLFLNDEYNIVAQARTGSGKTASFA 62 Query: 118 LSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL 177 + ++ ++ G + +++ RELA Q+ +E K ++K A YGG I + Sbjct: 63 IPLIELVNENNG-IEAIILTPTRELAIQVADEIESL-KGNKNLKIAKIYGGKAIYPQIKA 120 Query: 178 LKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRAT 237 LKN +IVV TPGR+ + ++L +VK F++DE D++L + +DV++I A Sbjct: 121 LKN----ANIVVGTPGRILDHINRGTLNLKNVKYFILDEADEMLN-MGFIKDVEKILNAC 175 Query: 238 PRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKL 297 +DK++++FSAT+ +EI + ++++ + I A ++Q Y+++ E E+ L Sbjct: 176 NKDKRILLFSATMPREILNLAKKYMGDYSFIKAKINA-----NIEQSYVEVNENERFEAL 230 Query: 298 AQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK 357 +LL + EF ++F K+ EL +L F A +HG + Q +R + FK + Sbjct: 231 CRLLKNKEFYG-LVFCKTKRDTKELASMLRDIGFKAGAIHGDLSQSQREKVIRLFKQKKI 289 Query: 358 RICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEE 417 RI ++TDV RGID+ +N INY L + Y+HR+GR GR G KG AIS ++ +E ++ Sbjct: 290 RILIATDVMSRGIDVNDLNCVINYHLPQNPESYMHRIGRTGRAGKKGKAISIINRREYKK 349 Query: 418 VLAKIQERFDVKIAEF 433 L I+ +KI + Sbjct: 350 -LRYIERAMKLKIKKL 364 >6CZ5-A nrPDB Length = 480 Score = 417 bits (1072), Expect = e-117, Method: Composition-based stats. Identities = 114/405 (28%), Positives = 184/405 (45%), Gaps = 30/405 (7%) Query: 54 GSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKT 113 G+ H F D + + I + P+ VQ+H IP D++ A++G GKT Sbjct: 45 GNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGCGKT 104 Query: 114 AVFVLSTLQQLDPV------------------PGEVAVVVICNARELAYQIRNEYLRFSK 155 A F+L L Q+ +V+ RELA QI E +FS Sbjct: 105 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFS- 163 Query: 156 YMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVID 215 Y V+ V YGG I + +++ + H++VATPGRL ++ I L K V+D Sbjct: 164 YRSRVRPCVVYGGADIGQQ---IRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLD 220 Query: 216 ECDKVLEELDMRRDVQEIFRA--TPRD--KQVMMFSATLSQEIRPICRRFLQNPLEIFVD 271 E D++L+ + ++ I P + MMFSAT +EI+ + R FL + + V Sbjct: 221 EADRMLD-MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVG 279 Query: 272 DEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQ-VIIFVKSTTRANELTKLLNASN 330 T + Q + +EE +K L LL+ + ++FV++ A+ L L Sbjct: 280 RVG-STSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEG 338 Query: 331 FPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQY 390 + ++HG Q +R F+ + I V+T V RG+DI + IN+DL ++ ++Y Sbjct: 339 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEY 398 Query: 391 LHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPE 435 +HR+GR GR G GLA SF + + + + + E P Sbjct: 399 VHRIGRTGRVGNLGLATSFFNERN-INITKDLLDLLVEAKQEVPS 442 >2I4I-A nrPDB Length = 417 Score = 417 bits (1072), Expect = e-117, Method: Composition-based stats. Identities = 114/405 (28%), Positives = 184/405 (45%), Gaps = 30/405 (7%) Query: 54 GSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKT 113 G+ H F D + + I + P+ VQ+H IP D++ A++G GKT Sbjct: 7 GNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKT 66 Query: 114 AVFVLSTLQQLDPV------------------PGEVAVVVICNARELAYQIRNEYLRFSK 155 A F+L L Q+ +V+ RELA QI E +FS Sbjct: 67 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFS- 125 Query: 156 YMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVID 215 Y V+ V YGG I + +++ + H++VATPGRL ++ I L K V+D Sbjct: 126 YRSRVRPCVVYGGADIGQQ---IRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLD 182 Query: 216 ECDKVLEELDMRRDVQEIFRA--TPRD--KQVMMFSATLSQEIRPICRRFLQNPLEIFVD 271 E D++L+ + ++ I P + MMFSAT +EI+ + R FL + + V Sbjct: 183 EADRMLD-MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVG 241 Query: 272 DEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQ-VIIFVKSTTRANELTKLLNASN 330 T + Q + +EE +K L LL+ + ++FV++ A+ L L Sbjct: 242 RVG-STSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEG 300 Query: 331 FPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQY 390 + ++HG Q +R F+ + I V+T V RG+DI + IN+DL ++ ++Y Sbjct: 301 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEY 360 Query: 391 LHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPE 435 +HR+GR GR G GLA SF + + + + + E P Sbjct: 361 VHRIGRTGRVGNLGLATSFFNERN-INITKDLLDLLVEAKQEVPS 404 >5DTU-A nrPDB Length = 475 Score = 417 bits (1072), Expect = e-117, Method: Composition-based stats. Identities = 105/423 (24%), Positives = 200/423 (47%), Gaps = 41/423 (9%) Query: 49 AGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKS 108 KG + +++ L L + G++ P+ +Q+ IP ++ D++ A + Sbjct: 29 GISTKGGSIPNPMRNWEESGLPRRLLDIVYRVGYDEPTPIQRAAIPIALQARDLIGVAVT 88 Query: 109 GLGKTAVFVLSTLQQLDPVPG--------EVAVVVICNARELAYQIRNEYLRFSKYMPDV 160 G GKTA F+L L + +P +++ REL QI +E +F+ + Sbjct: 89 GSGKTAAFLLPLLVYISELPPLTEYNKNDGPYALILAPTRELVQQIESEARKFADPL-GF 147 Query: 161 KTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKV 220 GG + + A L+N I+VATPGRL + + + S ++DE D++ Sbjct: 148 TVVSIVGGHSLEEQAFALRN---GAEIIVATPGRLVDCIERRLLVFSQCCYVIMDEADRM 204 Query: 221 LEELDMRRDVQEIFRATP-------------------------RDKQVMMFSATLSQEIR 255 +++ + +I A P R +Q MM++AT+ + Sbjct: 205 IDQ-GFEEPLTKILDALPVSNEKPDTEDAENPQLMSRYLGGRDRYRQTMMYTATMPPTVE 263 Query: 256 PICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQ-VIIFVK 314 I +++L+ P + + + + Q+ E ++ R+L ++L+ +F +I+FV Sbjct: 264 KIAKKYLRRPAIVTIGNAGEAVDTVEQRVEFIAGEDKRKRRLQEILNSGQFKPPIIVFVN 323 Query: 315 STTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIER 374 + K + + F +T+HG QE+R A A ++ + I V+TD+ GRGID+ Sbjct: 324 IKRNCEMVAKDIKSWGFSTVTLHGSKTQEQREASLAALRNGQAHILVATDLAGRGIDVPD 383 Query: 375 INLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERF-DVKIAEF 433 ++L +N+++ + + Y HR+GR GR G G+AI+F+ ED +V+ +++ I++ Sbjct: 384 VSLVVNFNMPSTIEAYTHRIGRTGRAGKSGVAITFLG-NEDADVMYDLKQIISKSSISKV 442 Query: 434 PEE 436 PEE Sbjct: 443 PEE 445 >3FHO-A nrPDB Length = 508 Score = 382 bits (980), Expect = e-106, Method: Composition-based stats. Identities = 107/362 (29%), Positives = 181/362 (50%), Gaps = 18/362 (4%) Query: 87 EVQQHTIPQSIHG--TDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAY 144 ++Q+ +P + +++ Q++SG GKTA F L+ L ++D + + + +RELA Sbjct: 144 KIQEKALPLLLSNPPRNMIGQSQSGTGKTAAFALTMLSRVDASVPKPQAICLAPSRELAR 203 Query: 145 QIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYI 204 QI + KY T + K IV+ TPG + L++ + + Sbjct: 204 QIMDVVTEMGKYTEV--------KTAFGIKDSVPKGAKIDAQIVIGTPGTVMDLMKRRQL 255 Query: 205 DLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQN 264 D +K FV+DE D +L++ + I PR+ Q+++FSAT S+ + RF N Sbjct: 256 DARDIKVFVLDEADNMLDQQGLGDQSMRIKHLLPRNTQIVLFSATFSERVEKYAERFAPN 315 Query: 265 PLEIFVDDEAKLTLHGLQQYYIKLEERE-KNRKLAQLLDDLEFNQVIIFVKSTTRANELT 323 EI + E +L++ G++Q Y+ + E K L +L L Q IIF K A E+ Sbjct: 316 ANEIRLKTE-ELSVEGIKQLYMDCQSEEHKYNVLVELYGLLTIGQSIIFCKKKDTAEEIA 374 Query: 324 KLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDL 383 + + A + G+++ +R A +F+ ++ V+T+V RGID+ ++NL +NYD+ Sbjct: 375 RRMTADGHTVACLTGNLEGAQRDAIMDSFRVGTSKVLVTTNVIARGIDVSQVNLVVNYDM 434 Query: 384 T------NEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPEEG 437 + YLHR+GR GRFG G++I+FV K+ E + IQE F I P + Sbjct: 435 PLDQAGRPDPQTYLHRIGRTGRFGRVGVSINFVHDKKSWEEMNAIQEYFQRPITRVPTDD 494 Query: 438 ID 439 + Sbjct: 495 YE 496 >6CB1-p nrPDB Length = 505 Score = 381 bits (979), Expect = e-106, Method: Composition-based stats. Identities = 124/426 (29%), Positives = 203/426 (47%), Gaps = 23/426 (5%) Query: 24 SKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFE 83 S+ +E+ E + NN G++ F++ L +AI GF Sbjct: 9 SRDSESTEEPVVDEKSTSKQNNAAPEGEQ-----TTCVEKFEELKLSQPTLKAIEKMGFT 63 Query: 84 HPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQL-----DPVPGEVAVVVICN 138 + VQ TIP + G DVL AK+G GKT F++ ++ L P G ++VI Sbjct: 64 TMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNG-TGIIVITP 122 Query: 139 ARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKAL 198 RELA QI ++ + GG ++AE L ++++ATPGRL Sbjct: 123 TRELALQIFGVARELMEFHSQ-TFGIVIGGANRRQEAEKLMK---GVNMLIATPGRLLDH 178 Query: 199 VRE-KYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPR-DKQVMMFSATLSQEIRP 256 ++ K ++K +IDE D++LE + ++++I + P D+Q M+FSAT + ++ Sbjct: 179 LQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQIIKILPNEDRQSMLFSATQTTKVED 237 Query: 257 ICRRFLQ-NPLEIFVDDEA-KLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVK 314 + R L+ PL I V E T GL+Q Y+ + ++ L L + ++I+F+ Sbjct: 238 LARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLS 297 Query: 315 STTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIER 374 S +LLN + P + +HG KQ++R + F + E+ I + TDV RG+DI Sbjct: 298 SCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPA 357 Query: 375 INLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIA--E 432 ++ I +D ++ Y+HRVGR R GTKG S + +E + + V + E Sbjct: 358 VDWIIQFDPPDDPRDYIHRVGRTAR-GTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYE 416 Query: 433 FPEEGI 438 FPE I Sbjct: 417 FPENKI 422 >4KBG-A nrPDB Length = 365 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 115/375 (30%), Positives = 189/375 (50%), Gaps = 14/375 (3%) Query: 62 TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 FKDF LKPE+ A+ G P+ +Q +P ++ G D++ QA++G GKT F L Sbjct: 1 MEFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIA 60 Query: 122 QQLDPVP---GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELL 178 ++L P + +V+ RELA Q+ +E + P +K YGGT K E L Sbjct: 61 ERLAPSQERGRKPRALVLTPTRELALQVASELTAVA---PHLKVVAVYGGTGYGKQKEAL 117 Query: 179 KNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATP 238 VVATPGR +R+ +DLS V+ V+DE D++L + +V+ + ATP Sbjct: 118 ---LRGADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLS-MGFEEEVEALLSATP 173 Query: 239 RDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLA 298 +Q ++FSATL + + R+++NP+ I V + +T ++ + R + L+ Sbjct: 174 PSRQTLLFSATLPSWAKRLAERYMKNPVLINVIKDEPVTY---EEEAVPAPVRGRLEVLS 230 Query: 299 QLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKR 358 LL ++ ++F ++ E+ + L PA +HG + Q ER AF+ E R Sbjct: 231 DLLYVASPDRAMVFTRTKAETEEIAQGLLRLGHPAQALHGDLSQGERERVLGAFRQGEVR 290 Query: 359 ICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEV 418 + V+TDV RG+DI +++L ++Y L + A+ Y HR GR GR G G + +E +V Sbjct: 291 VLVATDVAARGLDIPQVDLVVHYRLPDRAEAYQHRSGRTGRAGRGGRVVLLYGPRERRDV 350 Query: 419 LAKIQERFDVKIAEF 433 ++ + Sbjct: 351 -EALERAVGRRFKRV 364 >4W7S-A nrPDB Length = 463 Score = 373 bits (959), Expect = e-104, Method: Composition-based stats. Identities = 106/401 (26%), Positives = 190/401 (47%), Gaps = 35/401 (8%) Query: 53 KGSYVGIHSTGFKDFLL-KPELSRAII-DCGFEHPSEVQQHTIPQSIHG---TDVLCQAK 107 KG V +++ + +L R II + F P+ +Q+ TIP + D L A Sbjct: 38 KGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVAS 97 Query: 108 SGLGKTAVFVLSTLQQLDPVPG---------EVAVVVICNARELAYQIRNEYLRFSKYMP 158 +G GKT FV+ L ++ P +++ REL QI+ E + +K Sbjct: 98 TGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWS 157 Query: 159 -----DVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFV 213 D K GG + E+ + I+VATPGRL + + + V+ V Sbjct: 158 KESNYDCKVISIVGGHSLE---EISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLV 214 Query: 214 IDECDKVLEELDMRRDVQEIFRAT------PRDKQVMMFSATLSQEIRPICRRFLQNPL- 266 +DE DK+++ L V I ++Q +MF+AT++ I I ++Q P+ Sbjct: 215 LDEADKMID-LGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVY 273 Query: 267 -EIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKL 325 I V+ ++ + + +Y + +K +KL ++ + +IIF+ A+ L + Sbjct: 274 ATIGVETGSEPLIQQVVEY--ADNDEDKFKKLKPIVAKYD-PPIIIFINYKQTADWLAEK 330 Query: 326 LNAS-NFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLT 384 N +HG QE+R + F+ + +I ++T+V RG+DI ++L +N+ ++ Sbjct: 331 FQKETNMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQIS 390 Query: 385 NEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQER 425 + D Y+HR+GR GR +G A+SFVS+ EDE ++ ++ + Sbjct: 391 KKMDDYIHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKY 431 >5ZWN-y nrPDB Length = 588 Score = 373 bits (957), Expect = e-103, Method: Composition-based stats. Identities = 106/401 (26%), Positives = 190/401 (47%), Gaps = 35/401 (8%) Query: 53 KGSYVGIHSTGFKDFLL-KPELSRAII-DCGFEHPSEVQQHTIPQSIHG---TDVLCQAK 107 KG V +++ + +L R II + F P+ +Q+ TIP + D L A Sbjct: 163 KGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVAS 222 Query: 108 SGLGKTAVFVLSTLQQLDPVPG---------EVAVVVICNARELAYQIRNEYLRFSKYMP 158 +G GKT FV+ L ++ P +++ REL QI+ E + +K Sbjct: 223 TGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWS 282 Query: 159 -----DVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFV 213 D K GG + E+ + I+VATPGRL + + + V+ V Sbjct: 283 KESNYDCKVISIVGGHSLE---EISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLV 339 Query: 214 IDECDKVLEELDMRRDVQEIFRAT------PRDKQVMMFSATLSQEIRPICRRFLQNPL- 266 +DE DK+++ L V I ++Q +MF+AT++ I I ++Q P+ Sbjct: 340 LDEADKMID-LGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVY 398 Query: 267 -EIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKL 325 I V+ ++ + + +Y + +K +KL ++ + +IIF+ A+ L + Sbjct: 399 ATIGVETGSEPLIQQVVEY--ADNDEDKFKKLKPIVAKYD-PPIIIFINYKQTADWLAEK 455 Query: 326 LNAS-NFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLT 384 N +HG QE+R + F+ + +I ++T+V RG+DI ++L +N+ ++ Sbjct: 456 FQKETNMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQIS 515 Query: 385 NEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQER 425 + D Y+HR+GR GR +G A+SFVS+ EDE ++ ++ + Sbjct: 516 KKMDDYIHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKY 556 >4LJY-A nrPDB Length = 493 Score = 358 bits (918), Expect = 4e-99, Method: Composition-based stats. Identities = 95/394 (24%), Positives = 170/394 (43%), Gaps = 34/394 (8%) Query: 51 DKKGSYVGIHSTGFKDFLLKPELSRAIID-CGFEHPSEVQQHTIPQSIHGTDVLCQAKSG 109 KG+ T + L + I + F + +Q +P + G DV+ +K+G Sbjct: 39 KIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSLTPIQSQALPAIMSGRDVIGISKTG 98 Query: 110 LGKTAVFVLSTLQQLDPVPG------EVAVVVICNARELAYQIRNEYLRFSKYMPDVKTA 163 GKT ++L L+Q+ +++ RELA QI E +F++ +++ Sbjct: 99 SGKTISYLLPLLRQVKAQRPLSKHETGPMGLILAPTRELALQIHEEVTKFTEADTSIRSV 158 Query: 164 VFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVRE---KYIDLSHVKNFVIDECDKV 220 GG+ + K + + IVVATPGR ++ K + + V+DE D++ Sbjct: 159 CCTGGSEMKKQ---ITDLKRGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEADRL 215 Query: 221 LEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHG 280 + L + +I + DKQ ++FSAT ++R R L +P+ I ++ + + + Sbjct: 216 FD-LGFEPQITQIMKTVRPDKQCVLFSATFPNKLRSFAVRVLHSPISITINSKGMVNENV 274 Query: 281 LQQYYIKLEEREKNRKLAQLLDDLE--------------------FNQVIIFVKSTTRAN 320 Q++ I E EK L QL+ + + IIFV S + Sbjct: 275 KQKFRICHSEDEKFDNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICD 334 Query: 321 ELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAIN 380 ++K L + +H +ER+ + FK + I + T+V RG+++ ++L I Sbjct: 335 FISKKLLNAGIVTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLVII 394 Query: 381 YDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKE 414 Y+ QY+H GR R G AI+ + E Sbjct: 395 YNAVKTFAQYVHTTGRTARGSRSGTAITLLLHDE 428 >2Z0M-A nrPDB Length = 337 Score = 356 bits (915), Expect = 7e-99, Method: Composition-based stats. Identities = 112/345 (32%), Positives = 185/345 (53%), Gaps = 22/345 (6%) Query: 69 LKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVP 128 + ++ +AI + GF++ +EVQ TIP + G +V+ +AK+G GKTA + + L+ Sbjct: 1 MNEKIEQAIREMGFKNFTEVQSKTIPLMLQGKNVVVRAKTGSGKTAAYAIPILEL----- 55 Query: 129 GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIV 188 + +V+ REL Q+ + +YM D K A YGG P ++N IV Sbjct: 56 -GMKSLVVTPTRELTRQVASHIRDIGRYM-DTKVAEVYGGMPYKAQINRVRN----ADIV 109 Query: 189 VATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSA 248 VATPGRL L + IDLS + +IDE D + E + D++ I T K +FSA Sbjct: 110 VATPGRLLDLWSKGVIDLSSFEIVIIDEADLMFE-MGFIDDIKIILAQTSNRKITGLFSA 168 Query: 249 TLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQ 308 T+ +EIR + + F+ N EI EA + L ++ ++ +++ +++ Q L + + Sbjct: 169 TIPEEIRKVVKDFITNYEEI----EACIGLANVEHKFVHVKDDWRSKV--QALRENKDKG 222 Query: 309 VIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGR 368 VI+FV++ R +L +L + AI + G + Q R AF++ E + ++TDV R Sbjct: 223 VIVFVRTRNRVAKLVRLFDN----AIELRGDLPQSVRNRNIDAFREGEYDMLITTDVASR 278 Query: 369 GIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSK 413 G+DI + IN+D + Y+HR+GR GR G KG AI+F+ ++ Sbjct: 279 GLDIPLVEKVINFDAPQDLRTYIHRIGRTGRMGRKGEAITFILNE 323 >3SQW-A nrPDB Length = 579 Score = 326 bits (837), Expect = 9e-90, Method: Composition-based stats. Identities = 105/406 (25%), Positives = 185/406 (45%), Gaps = 35/406 (8%) Query: 65 KDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSI--HGTDVLCQAKSGLGKTAVFVLSTLQ 122 ++ +L E+ +AI F + VQQ TI + DV+ +AK+G GKT F++ Q Sbjct: 24 EEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQ 83 Query: 123 QLDPVPGE----VAVVVICNARELAYQIRNEYLRFSKYMPDVK---TAVFYGGTPISKDA 175 L + V V++ R+LA QI E + +K GGT A Sbjct: 84 HLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFR--A 141 Query: 176 ELLKNKDTAPHIVVATPGRLKALVREKYIDL-SHVKNFVIDECDKVLEELDMRRDVQEIF 234 + K P+IV+ATPGRL ++ + V V+DE D++LE + R D++ I Sbjct: 142 AMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLE-IGFRDDLETIS 200 Query: 235 -------RATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVD--DEAKLTLHGLQQYY 285 + + + ++FSATL +++ + + +F+D D+ + H Sbjct: 201 GILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQS 260 Query: 286 IKLEEREKNRKLA-------QLLDDLEFNQVIIFVKSTTRANELTKLLNAS---NFPAIT 335 + + E+ N A Q+ + + IIF + + L +L + P + Sbjct: 261 VVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILE 320 Query: 336 VHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVG 395 HG + Q +R + K FK E I V TDV RG+D ++ + + +E Y+HR+G Sbjct: 321 FHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIG 380 Query: 396 RAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPS 441 R R G +G ++ F+ E + ++++ ++ IA+ +E +PS Sbjct: 381 RTARSGKEGSSVLFICKDE-LPFVRELEDAKNIVIAK--QEKYEPS 423 >3I62-A nrPDB Length = 563 Score = 325 bits (833), Expect = 3e-89, Method: Composition-based stats. Identities = 105/406 (25%), Positives = 185/406 (45%), Gaps = 35/406 (8%) Query: 65 KDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSI--HGTDVLCQAKSGLGKTAVFVLSTLQ 122 ++ +L E+ +AI F + VQQ TI + DV+ +AK+G GKT F++ Q Sbjct: 75 EEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQ 134 Query: 123 QLDPVPGE----VAVVVICNARELAYQIRNEYLRFSKYMPDVK---TAVFYGGTPISKDA 175 L + V V++ R+LA QI E + +K GGT A Sbjct: 135 HLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFR--A 192 Query: 176 ELLKNKDTAPHIVVATPGRLKALVREKYIDL-SHVKNFVIDECDKVLEELDMRRDVQEIF 234 + K P+IV+ATPGRL ++ + V V+DE D++LE + R D++ I Sbjct: 193 AMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLE-IGFRDDLETIS 251 Query: 235 -------RATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVD--DEAKLTLHGLQQYY 285 + + + ++FSATL +++ + + +F+D D+ + H Sbjct: 252 GILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQS 311 Query: 286 IKLEEREKNRKLA-------QLLDDLEFNQVIIFVKSTTRANELTKLLNAS---NFPAIT 335 + + E+ N A Q+ + + IIF + + L +L + P + Sbjct: 312 VVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILE 371 Query: 336 VHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVG 395 HG + Q +R + K FK E I V TDV RG+D ++ + + +E Y+HR+G Sbjct: 372 FHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIG 431 Query: 396 RAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPS 441 R R G +G ++ F+ E + ++++ ++ IA+ +E +PS Sbjct: 432 RTARSGKEGSSVLFICKDE-LPFVRELEDAKNIVIAK--QEKYEPS 474 >1T6N-A nrPDB Length = 220 Score = 311 bits (798), Expect = 3e-85, Method: Composition-based stats. Identities = 157/222 (70%), Positives = 189/222 (85%), Gaps = 2/222 (0%) Query: 49 AGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKS 108 D KGSYV IHS+GF+DFLLKPEL RAI+DCGFEHPSEVQ IPQ+I G DVLCQAKS Sbjct: 1 GSDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKS 60 Query: 109 GLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGG 168 G+GKTAVFVL+TLQQL+PV G+V+V+V+C+ RELA+QI EY RFSKYMP+VK AVF+GG Sbjct: 61 GMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGG 120 Query: 169 TPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRR 228 I KD E+LK PHIVV TPGR+ AL R K ++L H+K+F++DECDK+LE+LDMRR Sbjct: 121 LSIKKDEEVLKK--NCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRR 178 Query: 229 DVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFV 270 DVQEIFR TP +KQVMMFSATLS+EIRP+CR+F+Q+P+EIFV Sbjct: 179 DVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFV 220 >5ZBZ-A nrPDB Length = 220 Score = 279 bits (713), Expect = 2e-75, Method: Composition-based stats. Identities = 74/210 (35%), Positives = 115/210 (54%), Gaps = 4/210 (1%) Query: 63 GFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQ 122 F D L L R I GFE PS +QQ I I G DV+ QA+SG GKTA F +S LQ Sbjct: 15 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 74 Query: 123 QLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKD 182 Q++ +V+ RELA QI+ + YM GGT + AE+ K + Sbjct: 75 QIELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVR--AEVQKLQM 131 Query: 183 TAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQ 242 APHI+V TPGR+ ++ +Y+ ++K FV+DE D++L + + +IF+ + Q Sbjct: 132 EAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQ 190 Query: 243 VMMFSATLSQEIRPICRRFLQNPLEIFVDD 272 V++ SAT+ ++ + ++F+++P+ I V Sbjct: 191 VVLLSATMPSDVLEVTKKFMRDPIRILVKK 220 >3BOR-A nrPDB Length = 237 Score = 278 bits (710), Expect = 5e-75, Method: Composition-based stats. Identities = 80/211 (37%), Positives = 115/211 (54%), Gaps = 4/211 (1%) Query: 63 GFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQ 122 F D LK L R I GFE PS +QQ I I G DV+ QA+SG GKTA F +S LQ Sbjct: 31 NFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQ 90 Query: 123 QLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKD 182 QL+ E +V+ RELA QI+ L YM GGT + E+ K + Sbjct: 91 QLEIEFKETQALVLAPTRELAQQIQKVILALGDYM-GATCHACIGGTNVRN--EMQKLQA 147 Query: 183 TAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQ 242 APHIVV TPGR+ ++ +Y+ +K FV+DE D++L + + EIF+ Q Sbjct: 148 EAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSR-GFKDQIYEIFQKLNTSIQ 206 Query: 243 VMMFSATLSQEIRPICRRFLQNPLEIFVDDE 273 V++ SAT+ ++ + ++F+++P+ I V E Sbjct: 207 VVLLSATMPTDVLEVTKKFMRDPIRILVKKE 237 >3FHC-B nrPDB Length = 235 Score = 277 bits (709), Expect = 6e-75, Method: Composition-based stats. Identities = 63/237 (26%), Positives = 114/237 (48%), Gaps = 9/237 (3%) Query: 42 DNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIH--G 99 DN N + + F++ LKP+L + + GF PS++Q++ +P + Sbjct: 5 DNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPP 64 Query: 100 TDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPD 159 +++ Q++SG GKTA FVL+ L Q++P + + ELA Q + K+ P+ Sbjct: 65 QNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPE 124 Query: 160 VKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKA-LVREKYIDLSHVKNFVIDECD 218 +K A G +L + + + IV+ TPG + + K+ID +K FV+DE D Sbjct: 125 LKLAYAVRGN------KLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 178 Query: 219 KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAK 275 ++ + I R PR+ Q+++FSAT + ++ + +P I + E + Sbjct: 179 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE 235 >3FMO-B nrPDB Length = 300 Score = 276 bits (705), Expect = 2e-74, Method: Composition-based stats. Identities = 63/235 (26%), Positives = 113/235 (48%), Gaps = 9/235 (3%) Query: 42 DNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIH--G 99 DN N + + F++ LKP+L + + GF PS++Q++ +P + Sbjct: 72 DNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPP 131 Query: 100 TDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPD 159 +++ Q++SG GKTA FVL+ L Q++P + + ELA Q + K+ P+ Sbjct: 132 QNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPE 191 Query: 160 VKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKA-LVREKYIDLSHVKNFVIDECD 218 +K A G +L + + + IV+ TPG + + K+ID +K FV+DE D Sbjct: 192 LKLAYAVRGN------KLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 245 Query: 219 KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDE 273 ++ + I R PR+ Q+++FSAT + ++ + +P I + E Sbjct: 246 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 300 >5GJU-A nrPDB Length = 205 Score = 271 bits (694), Expect = 3e-73, Method: Composition-based stats. Identities = 80/209 (38%), Positives = 110/209 (52%), Gaps = 4/209 (1%) Query: 62 TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 T F D LK + A+ D G+E PS +Q IP ++G DVL A++G GKTA F L L Sbjct: 1 TTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLL 60 Query: 122 QQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNK 181 Q LDP ++V+ RELA Q+ FSK+M V YGG L+ Sbjct: 61 QNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQ---LRAL 117 Query: 182 DTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDK 241 P IVV TPGRL ++ +DLS + V+DE D++L + DV+ I P Sbjct: 118 RQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADEML-RMGFIEDVETIMAQIPEGH 176 Query: 242 QVMMFSATLSQEIRPICRRFLQNPLEIFV 270 Q +FSAT+ + IR I RRF++ P E+ + Sbjct: 177 QTALFSATMPEAIRRITRRFMKEPQEVRI 205 >4Q48-A nrPDB Length = 525 Score = 264 bits (676), Expect = 4e-71, Method: Composition-based stats. Identities = 82/381 (21%), Positives = 139/381 (36%), Gaps = 37/381 (9%) Query: 72 ELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEV 131 L + I G+ VQ + Q G + L +G GK+ + L +L L P G V Sbjct: 14 HLLQTIW--GYPAFRGVQGEIVQQVAEGGNALVLMPTGGGKSLCYQLPSL--LRPGTGIV 69 Query: 132 AVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKN--KDTAPHIVV 189 +I ++ +R +R A F T + +A +++ ++ Sbjct: 70 VSPLIALMKDQVDTLRQNGVR----------AAFLNSTLLPHEAREVEDALLRGDLDLLY 119 Query: 190 ATPGRLKALVREKYIDLSHVKNFVIDECDKVLEE-LDMRRDVQEI------FRATPRDKQ 242 P RL ++ + V F IDE V + D R + Q++ F PR Sbjct: 120 VAPERLLMPRTLDLLERAPVALFAIDEAHCVSQWGHDFRPEYQQLSVLAERFPELPR--- 176 Query: 243 VMMFSATLSQEIRPICRRFLQ---NPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQ 299 + +AT + R + L+ P + D + QY + L++ K + L Sbjct: 177 -VALTATADERTRADIKSVLRLEDAPQFVSSFDRPNI------QYRVGLKDSPKTQLLHF 229 Query: 300 LLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRI 359 + ++ + I++ S E K L A A+ H + ER + F + E I Sbjct: 230 IREEHPGDAGIVYCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLNEEGVI 289 Query: 360 CVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVL 419 +T FG GID + + DL + Y GRAGR G A + V Sbjct: 290 VCATVAFGMGIDKPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTAWMVYGLSDVVNVR 349 Query: 420 AKI-QERFDVKIAEFPEEGID 439 + Q ++ +D Sbjct: 350 RMLAQSDAPEEVKRVEASKLD 370 >1QVA-A nrPDB Length = 223 Score = 263 bits (673), Expect = 9e-71, Method: Composition-based stats. Identities = 72/225 (32%), Positives = 117/225 (52%), Gaps = 7/225 (3%) Query: 46 NTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQ 105 + + +Y + F D L +L R + GFE PS +QQ I I G DVL Q Sbjct: 6 DIEESQIQTNYQKVVYK-FDDMELDEQLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQ 64 Query: 106 AKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVF 165 A+SG GKT F ++ LQ++D +++ RELA QI+ + + +M D+K Sbjct: 65 AQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHM-DIKVHAC 123 Query: 166 YGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELD 225 GGT +DAE L++ IVV TPGR+ ++ + +K F++DE D++L Sbjct: 124 IGGTSFVEDAEGLRD----AQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSS-G 178 Query: 226 MRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFV 270 + + +IF P QV++ SAT+ ++ + +F++NP+ I V Sbjct: 179 FKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILV 223 >1WRB-A nrPDB Length = 253 Score = 261 bits (667), Expect = 4e-70, Method: Composition-based stats. Identities = 65/256 (25%), Positives = 116/256 (45%), Gaps = 20/256 (7%) Query: 42 DNNNNTAAGDKKGSYVG-IHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGT 100 D ++ Y F + L P + I+ ++ P+ +Q++ IP + Sbjct: 2 DKYDSIPVSVTGPDYSATNVIENFDELKLDPTIRNNILLASYQRPTPIQKNAIPAILEHR 61 Query: 101 DVLCQAKSGLGKTAVFVLSTLQQL---------DPVPGEVAVVVICNARELAYQIRNEYL 151 D++ A++G GKTA F++ + L +++ RELA QI +E Sbjct: 62 DIMACAQTGSGKTAAFLIPIINHLVCQDLNQQRYSKTAYPKCLILAPTRELAIQILSESQ 121 Query: 152 RFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKN 211 +FS P +++ V YGG ++ H++VATPGRL + + I L K Sbjct: 122 KFSLNTP-LRSCVVYGGADTHSQ---IREVQMGCHLLVATPGRLVDFIEKNKISLEFCKY 177 Query: 212 FVIDECDKVLEELDMRRDVQEIF--RATPR--DKQVMMFSATLSQEIRPICRRFLQNPLE 267 V+DE D++L+ + +++I P ++Q +MFSAT +EI+ + FL N + Sbjct: 178 IVLDEADRMLD-MGFEPQIRKIIEESNMPSGINRQTLMFSATFPKEIQKLAADFLYNYIF 236 Query: 268 IFVDDEAKLTLHGLQQ 283 + V T ++Q Sbjct: 237 MTVGRVG-STSDSIKQ 251 >1VEC-A nrPDB Length = 206 Score = 261 bits (666), Expect = 6e-70, Method: Composition-based stats. Identities = 68/206 (33%), Positives = 119/206 (57%), Gaps = 4/206 (1%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 F+D+ LK EL I + G+E PS +Q+ +IP ++ G D+L +AK+G GK+ +++ L++ Sbjct: 5 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 64 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 LD + +VI RELA Q+ ++ SK+M K GGT + D + D Sbjct: 65 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDD---IMRLDD 121 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 H+V+ATPGR+ L+++ + HV+ V+DE DK+L + D + +++I P+++Q+ Sbjct: 122 TVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMEDIILTLPKNRQI 180 Query: 244 MMFSATLSQEIRPICRRFLQNPLEIF 269 +++SAT ++ L+ P EI Sbjct: 181 LLYSATFPLSVQKFMNSHLEKPYEIN 206 >2GXQ-A nrPDB Length = 207 Score = 256 bits (653), Expect = 2e-68, Method: Composition-based stats. Identities = 73/214 (34%), Positives = 113/214 (52%), Gaps = 10/214 (4%) Query: 62 TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 FKDF LKPE+ A+ G P+ +Q +P ++ G D++ QA++G GKT F L Sbjct: 1 MEFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIA 60 Query: 122 QQLDPVP---GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELL 178 ++L P + +V+ RELA Q+ +E + P +K YGGT K E L Sbjct: 61 ERLAPSQERGRKPRALVLTPTRELALQVASELTAVA---PHLKVVAVYGGTGYGKQKEAL 117 Query: 179 KNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATP 238 VVATPGR +R+ +DLS V+ V+DE D++L + +V+ + ATP Sbjct: 118 ---LRGADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLS-MGFEEEVEALLSATP 173 Query: 239 RDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDD 272 +Q ++FSATL + + R+++NP+ I V Sbjct: 174 PSRQTLLFSATLPSWAKRLAERYMKNPVLINVIK 207 >4PX9-A nrPDB Length = 292 Score = 254 bits (648), Expect = 8e-68, Method: Composition-based stats. Identities = 69/241 (28%), Positives = 107/241 (44%), Gaps = 27/241 (11%) Query: 54 GSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKT 113 G+ H F D + + I + P+ VQ+H IP D++ A++G GKT Sbjct: 57 GNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKT 116 Query: 114 AVFVLSTLQQLDPV------------------PGEVAVVVICNARELAYQIRNEYLRFSK 155 A F+L L Q+ +V+ RELA QI E +FS Sbjct: 117 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFS- 175 Query: 156 YMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVID 215 Y V+ V YGG I + +++ + H++VATPGRL ++ I L K V+D Sbjct: 176 YRSRVRPCVVYGGADIGQQ---IRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLD 232 Query: 216 ECDKVLEELDMRRDVQEIFRA--TPRD--KQVMMFSATLSQEIRPICRRFLQNPLEIFVD 271 E D++L+ + ++ I P + MMFSAT +EI+ + R FL + + V Sbjct: 233 EADRMLD-MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVG 291 Query: 272 D 272 Sbjct: 292 R 292 >5H1Y-A nrPDB Length = 281 Score = 248 bits (634), Expect = 3e-66, Method: Composition-based stats. Identities = 67/244 (27%), Positives = 117/244 (47%), Gaps = 17/244 (6%) Query: 52 KKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLG 111 +G + FK+ + R + G HP+ +Q IP + G D++ A +G G Sbjct: 42 VEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSG 101 Query: 112 KTAVFVLST----LQQLDPVP----GEVAVVVICNARELAYQ---IRNEYLRFS--KYMP 158 KT VF L L+Q +P ++IC +RELA Q I Y R P Sbjct: 102 KTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSP 161 Query: 159 DVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECD 218 ++ A+ GG + + E +++ H++VATPGRL L+++K + L + +DE D Sbjct: 162 LLRCALCIGGMSVKEQMETIRH---GVHMMVATPGRLMDLLQKKMVSLDICRYLALDEAD 218 Query: 219 KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTL 278 ++++ + D++ IF +Q ++FSAT+ ++I+ + L P+ I V +L Sbjct: 219 RMID-MGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASL 277 Query: 279 HGLQ 282 +Q Sbjct: 278 DVIQ 281 >2OXC-A nrPDB Length = 230 Score = 247 bits (631), Expect = 7e-66, Method: Composition-based stats. Identities = 68/221 (30%), Positives = 111/221 (50%), Gaps = 4/221 (1%) Query: 52 KKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLG 111 + G + F+ LL + + GFE PS VQ IP G D++ QAKSG G Sbjct: 14 RTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTG 73 Query: 112 KTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPI 171 KT VF L L ++++ RE+A QI + M ++ VF GGTP+ Sbjct: 74 KTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPL 133 Query: 172 SKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQ 231 S+D LK HI V +PGR+K L+ Y++ ++ F++DE DK+LEE + + Sbjct: 134 SQDKTRLKK----CHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQIN 189 Query: 232 EIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDD 272 I+ + P KQ++ SAT + + +++++P + ++ Sbjct: 190 WIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNS 230 >3FE2-A nrPDB Length = 242 Score = 247 bits (630), Expect = 9e-66, Method: Composition-based stats. Identities = 54/240 (22%), Positives = 106/240 (44%), Gaps = 10/240 (4%) Query: 37 SATEGDNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQS 96 +A E + + +G F + + I F P+ +Q P + Sbjct: 4 TAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVA 63 Query: 97 IHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVP-----GEVAVVVICNARELAYQIRNEYL 151 + G D++ A++G GKT ++L + ++ P +V+ RELA Q++ Sbjct: 64 LSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAA 123 Query: 152 RFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKN 211 + + +K+ YGG P +++ + I +ATPGRL + +L Sbjct: 124 EYCRAC-RLKSTCIYGGAPKGPQ---IRDLERGVEICIATPGRLIDFLECGKTNLRRTTY 179 Query: 212 FVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVD 271 V+DE D++L+ + +++I D+Q +M+SAT +E+R + FL++ + I + Sbjct: 180 LVLDEADRMLD-MGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIG 238 >2KBE-A nrPDB Length = 226 Score = 243 bits (621), Expect = 9e-65, Method: Composition-based stats. Identities = 60/227 (26%), Positives = 107/227 (47%), Gaps = 10/227 (4%) Query: 46 NTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHG--TDVL 103 A + + F + L PEL + I F+ PS++Q+ +P +H +++ Sbjct: 6 KLADIQADPNSPLYSAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMI 65 Query: 104 CQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTA 163 Q++SG GKTA F L+ L +++P + + +RELA Q K+ Sbjct: 66 AQSQSGTGKTAAFSLTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTK----- 120 Query: 164 VFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEE 223 I D+ KNK ++V TPG + L+R K + L +K FV+DE D +L++ Sbjct: 121 --ITSQLIVPDS-FEKNKQINAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQ 177 Query: 224 LDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFV 270 + + R P+D Q+++FSAT + +R ++ + N + + Sbjct: 178 QGLGDQCIRVKRFLPKDTQLVLFSATFADAVRQYAKKIVPNANTLEL 224 >1Q0U-A nrPDB Length = 219 Score = 242 bits (618), Expect = 2e-64, Method: Composition-based stats. Identities = 68/214 (31%), Positives = 121/214 (56%), Gaps = 7/214 (3%) Query: 62 TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 T F F +P + AI F P+E+Q+ IP ++ G ++ Q+++G GKT ++L + Sbjct: 4 TQFTRFPFQPFIIEAIKTLRFYKPTEIQERIIPGALRGESMVGQSQTGTGKTHAYLLPIM 63 Query: 122 QQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTA---VFYGGTPISKDAELL 178 +++ P EV V+ RELA QI +E L+ +K+ P + GGT K L Sbjct: 64 EKIKPERAEVQAVITAPTRELATQIYHETLKITKFCPKDRMIVARCLIGGTDKQK---AL 120 Query: 179 KNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATP 238 + + PHIV+ TPGR+ +RE+ +D+ V+DE D +L+ + DV +I P Sbjct: 121 EKLNVQPHIVIGTPGRINDFIREQALDVHTAHILVVDEADLMLD-MGFITDVDQIAARMP 179 Query: 239 RDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDD 272 +D Q+++FSAT+ ++++P +++++NP + V + Sbjct: 180 KDLQMLVFSATIPEKLKPFLKKYMENPTFVHVLE 213 >5GVS-A nrPDB Length = 231 Score = 241 bits (616), Expect = 3e-64, Method: Composition-based stats. Identities = 65/233 (27%), Positives = 113/233 (48%), Gaps = 17/233 (7%) Query: 52 KKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLG 111 +G + FK+ + R + G HP+ +Q IP + G D++ A +G G Sbjct: 3 VEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSG 62 Query: 112 KTAVFVLST----LQQLDPVP----GEVAVVVICNARELAYQ---IRNEYLRFS--KYMP 158 KT VF L L+Q +P ++IC +RELA Q I Y R P Sbjct: 63 KTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSP 122 Query: 159 DVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECD 218 ++ A+ GG + + E +++ H++VATPGRL L+++K + L + +DE D Sbjct: 123 LLRCALCIGGMSVKEQMETIRH---GVHMMVATPGRLMDLLQKKMVSLDICRYLALDEAD 179 Query: 219 KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVD 271 ++++ + D++ IF +Q ++FSAT+ ++I+ + L P+ I V Sbjct: 180 RMID-MGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVG 231 >3IUY-A nrPDB Length = 228 Score = 241 bits (616), Expect = 4e-64, Method: Composition-based stats. Identities = 61/221 (27%), Positives = 108/221 (48%), Gaps = 13/221 (5%) Query: 57 VGIHSTGFKD-FLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAV 115 + + FKD F P+L ++II G P+ +Q P + G D++ A++G GKT Sbjct: 14 IPKPTCRFKDAFQQYPDLLKSIIRVGILKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLS 73 Query: 116 FVLSTLQQLDPVP------GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGT 169 +++ LD P ++V+ RELA + E ++S +K+ YGG Sbjct: 74 YLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYS--YKGLKSICIYGGR 131 Query: 170 PISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRD 229 + E + I++ATPGRL L ++L + VIDE DK+L+ ++ Sbjct: 132 NRNGQIE---DISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLD-MEFEPQ 187 Query: 230 VQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFV 270 +++I D+Q +M SAT +R + +L++P+ ++V Sbjct: 188 IRKILLDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYV 228 >6CRM-A nrPDB Length = 541 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 68/382 (17%), Positives = 135/382 (35%), Gaps = 35/382 (9%) Query: 69 LKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVP 128 L ++ + G++ Q I + G D L +G GK+ + + L + Sbjct: 32 LAKQVLQETF--GYQQFRPGQATIIDAVLEGRDCLVVMPTGGGKSLCYQIPAL--VKTGL 87 Query: 129 GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTA-PHI 187 V +I ++ Q+ V A + +L T + Sbjct: 88 TIVVSPLISLMKDQVDQLLAN---------GVAAACLNSTQSREEQQAVLAGCRTGQVRL 138 Query: 188 VVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEE-LDMRRDVQEI------FRATPRD 240 + P RL + + +DE + + D R + + F A P Sbjct: 139 LYIAPERLMMDNFIDTLGYWDLAMVAVDEAHCISQWGHDFRPEYAALGQLRARFPAVP-- 196 Query: 241 KQVMMFSATLSQEIRPICRRFL--QNP-LEIFVDDEAKLTLHGLQQYYIKLEEREKNRKL 297 M +AT R R L +P +EI D + Y+ +E+ + +L Sbjct: 197 --FMALTATADDTTRRDIVRLLGLDDPLIEISSFDRPNIR-------YMLMEKFKPLDQL 247 Query: 298 AQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEK 357 + + + II+ S + + L + A H ++ E R + + F+ + Sbjct: 248 MRYVQEQRGKSGIIYCNSRAKVEDTAARLQSRGISAAAYHAGLEHEVRASVQEKFQRDDL 307 Query: 358 RICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEE 417 +I V+T FG GI+ + +++D+ + Y GRAGR G A+ F + Sbjct: 308 QIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADMAW 367 Query: 418 VLAKIQERFDVKIAEFPEEGID 439 + ++E+ + + ++ Sbjct: 368 LRRCLEEKAPGPLQDIERHKLN 389 >6AIC-A nrPDB Length = 214 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 58/211 (27%), Positives = 113/211 (53%), Gaps = 7/211 (3%) Query: 63 GFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQ 122 FK+ + +++ GF+ P+ +Q+ +IP ++ G D+L QA++G GKT F + ++ Sbjct: 3 NFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPLIE 62 Query: 123 QLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKD 182 ++ G V +++ RELA Q+ + FS+ V+ +GG PI + + LK Sbjct: 63 KVVGKQG-VQSLILAPTRELAMQVAEQLREFSRGQ-GVQVVTVFGGMPIERQIKALKK-- 118 Query: 183 TAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPR-DK 241 P IVV TPGR+ + + + + ++DE D+++ + D++ I P + Sbjct: 119 -GPQIVVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMMN-MGFIDDMRFIMDKIPAVQR 176 Query: 242 QVMMFSATLSQEIRPICRRFLQNPLEIFVDD 272 Q M+FSAT+ + I+ + ++F+++P I + Sbjct: 177 QTMLFSATMPKAIQALVQQFMKSPKIIKTMN 207 >3BER-A nrPDB Length = 249 Score = 236 bits (603), Expect = 1e-62, Method: Composition-based stats. Identities = 68/212 (32%), Positives = 115/212 (54%), Gaps = 6/212 (2%) Query: 60 HSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLS 119 + FKD + L A G+ P+++Q IP ++ G D++ A++G GKT F L Sbjct: 41 ETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALP 100 Query: 120 TLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLK 179 L L P + +V+ RELA+QI ++ + V++AV GG + L Sbjct: 101 ILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALA 159 Query: 180 NKDTAPHIVVATPGRLKALVRE-KYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATP 238 K PHI++ATPGRL + K +L +K V+DE D++L +D +V +I + P Sbjct: 160 KK---PHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILN-MDFETEVDKILKVIP 215 Query: 239 RDKQVMMFSATLSQEIRPICRRFLQNPLEIFV 270 RD++ +FSAT++++++ + R L+NP++ V Sbjct: 216 RDRKTFLFSATMTKKVQKLQRAALKNPVKCAV 247 >1OYY-A nrPDB Length = 523 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 67/371 (18%), Positives = 134/371 (36%), Gaps = 35/371 (9%) Query: 81 GFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNAR 140 G++ Q+ I + G D L +G GK+ + + L L V +I + Sbjct: 22 GYQQFRPGQEEIIDTVLSGRDCLVVMPTGGGKSLCYQIPAL--LLNGLTVVVSPLISLMK 79 Query: 141 ELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTA-PHIVVATPGRL-KAL 198 + Q++ V A + E++ T ++ P RL Sbjct: 80 DQVDQLQAN---------GVAAACLNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDN 130 Query: 199 VREKYIDLSHVKNFVIDECDKVLEE-LDMRR------DVQEIFRATPRDKQVMMFSATLS 251 E + V +DE + + D R +++ F P M +AT Sbjct: 131 FLEHLAHWNPV-LLAVDEAHCISQWGHDFRPEYAALGQLRQRFPTLP----FMALTATAD 185 Query: 252 QEIRPICRRFL--QNP-LEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQ 308 R R L +P ++I D + Y+ +E+ + +L + + + Sbjct: 186 DTTRQDIVRLLGLNDPLIQISSFDRPNIR-------YMLMEKFKPLDQLMRYVQEQRGKS 238 Query: 309 VIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGR 368 II+ S + + L + A H ++ R + F+ + +I V+T FG Sbjct: 239 GIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGM 298 Query: 369 GIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDV 428 GI+ + +++D+ + Y GRAGR G A+ F + + ++E+ Sbjct: 299 GINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADMAWLRRCLEEKPQG 358 Query: 429 KIAEFPEEGID 439 ++ + ++ Sbjct: 359 QLQDIERHKLN 369 >5V9X-A nrPDB Length = 877 Score = 225 bits (574), Expect = 3e-59, Method: Composition-based stats. Identities = 88/433 (20%), Positives = 145/433 (33%), Gaps = 70/433 (16%) Query: 73 LSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKT-AVFVLSTLQQLDPVPGE- 130 L+R F P+ Q G + L A +G GKT A F+ + + DP Sbjct: 36 LTREWFTTAFAAPTPAQADAWSAISEGNNTLVIAPTGSGKTLAAFLWAIDRLADPAREPS 95 Query: 131 --VAVVVICNARELAY-----------QIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL 177 V+ + + LA I R P + V G TP ++ + Sbjct: 96 QGTQVLYVSPLKALAVDVERNLRTPLTGITRVAERHGLPAPSITVGVRSGDTPPNQRRAM 155 Query: 178 LKNKDTAPHIVVATPGRLKALVREKYID-LSHVKNFVIDECDKVLEE---LDMRRDVQEI 233 + N P +++ TP L ++ + L+ V+ ++DE V + ++ + Sbjct: 156 IANP---PDVLITTPESLFLMLTSAARETLTSVRTVIVDEVHAVAATKRGAHLALSLERL 212 Query: 234 FRATPRDKQVMMFSATL--SQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEER 291 + Q + SAT+ +E+ Q P I AK +Q + Sbjct: 213 DQLLDTPAQRIGLSATVRPPEEVARFLSG--QAPTTIVCPPAAKTFDLSVQVPVPDMANL 270 Query: 292 EKNRKLAQLLDDL-----EFNQVIIFVKSTTRANELTKLLN------------------- 327 + N + + + N I+F S A LT LN Sbjct: 271 DNNSIWPDVEERIVDLVEAHNSSIVFANSRRLAERLTSRLNEIHAERSGIELPAGPNPEV 330 Query: 328 -------------ASNFP---AITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGID 371 A+ P A HG + +E+R K R V+T GID Sbjct: 331 GGGAPAHLMGSGQANGAPPLLARAHHGSVSKEQRAQVEDDLKSGRLRAVVATSSLELGID 390 Query: 372 IERINLAINYDLTNEADQYLHRVGRAG-RFGTKGLAISFVSSKEDEEVLAKIQERF---D 427 + ++L I + L RVGRAG + G + F + D A +R D Sbjct: 391 MGAVDLVIQVEAPPSVASGLQRVGRAGHQVGEISQGVLFPKHRTDLIGCAVTVQRMQTGD 450 Query: 428 VKIAEFPEEGIDP 440 ++ P +D Sbjct: 451 IETLRVPANPLDV 463 >2PL3-A nrPDB Length = 236 Score = 224 bits (572), Expect = 5e-59, Method: Composition-based stats. Identities = 62/221 (28%), Positives = 112/221 (50%), Gaps = 11/221 (4%) Query: 59 IHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVL 118 T F DF L + + + + + +E+Q+ TI ++ G DVL AK+G GKT F++ Sbjct: 22 NEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLV 81 Query: 119 STLQQLDPVPG----EVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKD 174 L+ L + + V++I RELAYQ + K D + GG + + Sbjct: 82 PVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGK-NHDFSAGLIIGGKDLKHE 140 Query: 175 AELLKNKDTAPHIVVATPGRLKALVREKY-IDLSHVKNFVIDECDKVLEELDMRRDVQEI 233 AE + N +I+V TPGRL + E + ++ V+DE D++L+ + + + Sbjct: 141 AERINNI----NILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILD-MGFADTMNAV 195 Query: 234 FRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEA 274 P+ +Q ++FSAT ++ ++ + R L+NP ++V ++A Sbjct: 196 IENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKA 236 >3DKP-A nrPDB Length = 245 Score = 215 bits (548), Expect = 3e-56, Method: Composition-based stats. Identities = 65/233 (27%), Positives = 110/233 (47%), Gaps = 13/233 (5%) Query: 52 KKGSYVGIHSTGFK----DFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAK 107 +G+ + F+ ++ + L + I+D GF+ P+ +Q IP +HG ++L A Sbjct: 15 VQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAP 74 Query: 108 SGLGKTAVFVLSTLQQLD-PVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFY 166 +G GKT F + L QL P ++I RELA QI E ++ S+ + + + Sbjct: 75 TGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGT-GFRIHMIH 133 Query: 167 GGTPISKDAELLKNKDTAPHIVVATPGRLKALVREK--YIDLSHVKNFVIDECDKVLEEL 224 +K +K I+V TP RL L+++ IDL+ V+ V+DE DK+ E+ Sbjct: 134 KAAVAAKKFGPKSSKKF--DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDG 191 Query: 225 --DMRRDVQEIFRATPRDK-QVMMFSATLSQEIRPICRRFLQNPLEIFVDDEA 274 R + IF A K + MFSAT + ++ C+ L N + + + Sbjct: 192 KTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARN 244 >3LY5-A nrPDB Length = 262 Score = 207 bits (526), Expect = 1e-53, Method: Composition-based stats. Identities = 63/243 (25%), Positives = 113/243 (46%), Gaps = 24/243 (9%) Query: 45 NNTAAGDKK------GSYVGIHSTGFKDFLL-------KPELSRAIIDCGFEHPSEVQQH 91 NN D S + F+D +AI + GF + +E+Q Sbjct: 24 NNVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHK 83 Query: 92 TIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQ---QLDPVP-GEVAVVVICNARELAYQIR 147 +I + G D+L AK+G GKT F++ ++ +L +P V+++ RELA Q Sbjct: 84 SIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTRELAMQTF 143 Query: 148 NEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVRE-KYIDL 206 + + GG+ S +A+ L N +I+VATPGRL ++ Sbjct: 144 GVLKELMTHHVH-TYGLIMGGSNRSAEAQKLGN---GINIIVATPGRLLDHMQNTPGFMY 199 Query: 207 SHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQN-P 265 +++ VIDE D++L+ + ++++I + P +Q M+FSAT ++++ + R L+ P Sbjct: 200 KNLQCLVIDEADRILD-VGFEEELKQIIKLLPTRRQTMLFSATQTRKVEDLARISLKKEP 258 Query: 266 LEI 268 L + Sbjct: 259 LYV 261 >5LBA-B nrPDB Length = 445 Score = 205 bits (521), Expect = 4e-53, Method: Composition-based stats. Identities = 67/394 (17%), Positives = 136/394 (34%), Gaps = 33/394 (8%) Query: 71 PELSRAIIDCGFEHP-SEVQQHTIPQSIHG-TDVLCQAKSGLGKTAVFVLSTLQQLDPVP 128 + + GF+ + +Q+ + G DV +G GK+ + L L L Sbjct: 9 RSTLKKVF--GFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL--LAKGI 64 Query: 129 GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT---AP 185 V +I ++ + +R S + + ELL + + Sbjct: 65 TIVVSPLIALIQDQVDHLLTLKVRVSSLNSKL---------SAQERKELLADLEREKPQT 115 Query: 186 HIVVATPG----RLKALVREKYIDLSHVKNFVIDECDKVLEE-LDMRRDVQEI--FRATP 238 I+ TP + + V+DE V + D R D + R+ Sbjct: 116 KILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRL 175 Query: 239 RDKQVMMFSATLSQEIRP--ICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEE---REK 293 + +AT + +++ L+ P+ IF + L Q+ + + K Sbjct: 176 GHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLK 235 Query: 294 NRKLAQLLDDLEFNQV---IIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYK 350 + L L + + I++ ++ +L L+ A H +K ER Sbjct: 236 DFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQN 295 Query: 351 AFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFV 410 + + + + V+T FG G+D + ++++ Y GRAGR G + Sbjct: 296 DWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYY 355 Query: 411 SSKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYL 444 S + ++V I++ + + D +T + Sbjct: 356 SRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIM 389 >5LB8-A nrPDB Length = 518 Score = 205 bits (521), Expect = 4e-53, Method: Composition-based stats. Identities = 67/394 (17%), Positives = 136/394 (34%), Gaps = 33/394 (8%) Query: 71 PELSRAIIDCGFEHP-SEVQQHTIPQSIHG-TDVLCQAKSGLGKTAVFVLSTLQQLDPVP 128 + + GF+ + +Q+ + G DV +G GK+ + L L L Sbjct: 9 RSTLKKVF--GFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL--LAKGI 64 Query: 129 GEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT---AP 185 V +I ++ + +R S + + ELL + + Sbjct: 65 TIVVSPLIALIQDQVDHLLTLKVRVSSLNSKL---------SAQERKELLADLEREKPQT 115 Query: 186 HIVVATPG----RLKALVREKYIDLSHVKNFVIDECDKVLEE-LDMRRDVQEI--FRATP 238 I+ TP + + V+DE V + D R D + R+ Sbjct: 116 KILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRL 175 Query: 239 RDKQVMMFSATLSQEIRP--ICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEE---REK 293 + +AT + +++ L+ P+ IF + L Q+ + + K Sbjct: 176 GHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLK 235 Query: 294 NRKLAQLLDDLEFNQV---IIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYK 350 + L L + + I++ ++ +L L+ A H +K ER Sbjct: 236 DFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQN 295 Query: 351 AFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFV 410 + + + + V+T FG G+D + ++++ Y GRAGR G + Sbjct: 296 DWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYY 355 Query: 411 SSKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYL 444 S + ++V I++ + + D +T + Sbjct: 356 SRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIM 389 >5LST-A nrPDB Length = 693 Score = 192 bits (489), Expect = 2e-49, Method: Composition-based stats. Identities = 77/379 (20%), Positives = 134/379 (35%), Gaps = 41/379 (10%) Query: 70 KPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPG 129 E+ +A+ G + Q+ + + + G L +G GK+ + L L L Sbjct: 43 PAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPAL--LYSRRS 100 Query: 130 EVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTA-PHIV 188 +V+ L + S P +K A + G + +L+ A H++ Sbjct: 101 PCLTLVVSPLLSLMD------DQVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVL 154 Query: 189 VATPGRLKALVREK-YIDLSHVKNFVIDECDKVLEE-LDMRRDVQEIFRATPRDKQV--- 243 + TP L L V IDE + + + R + + V Sbjct: 155 MLTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCF 214 Query: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLE---EREKNRKLAQL 300 + +AT ++ + L V +E L + L +R+ ++ L L Sbjct: 215 LGLTATATRRTASDVAQHL------AVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTL 268 Query: 301 LDDLEF---NQVIIFVKSTTRANELTKLL----NASNFP----------AITVHGHMKQE 343 L F + +II+ + LL +A+ P A H M Sbjct: 269 LQGKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSR 328 Query: 344 ERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTK 403 ER +AF + R+ V+T FG G+D + ++ L + Y+ VGRAGR G Sbjct: 329 ERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQP 388 Query: 404 GLAISFVSSK-EDEEVLAK 421 F+ + ED L + Sbjct: 389 AHCHLFLQPQGEDLRELRR 407 >4CDG-A nrPDB Length = 673 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 68/344 (19%), Positives = 123/344 (35%), Gaps = 36/344 (10%) Query: 89 QQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRN 148 Q I ++ G D +G GK+ + L + P VVI R L I + Sbjct: 39 QLEAINAALLGEDCFILMPTGGGKSLCYQLPA--CVSPG----VTVVISPLRSL---IVD 89 Query: 149 EYLRFSKYMPDVKTAVFYGGTPISKDAEL---LKNKDTAPHIVVATPG------RLKALV 199 + + + D+ G S+ + L KD ++ TP RL + + Sbjct: 90 QVQKLTSL--DIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL 147 Query: 200 REKYIDLSHVKNFVIDECDKVLEE-LDMRRDVQEI--FRATPRDKQVMMFSATLSQEIRP 256 + + FVIDE V + D R+D + + R VM +AT + ++ Sbjct: 148 EN-LYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQK 206 Query: 257 ICR---RFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREK--NRKLAQLLDDLEFNQVII 311 + L+ + + L +YY+ ++ +K L + ++ II Sbjct: 207 DILTQLKILRPQVFSMSFNRHNL------KYYVLPKKPKKVAFDCLEWIRKHHPYDSGII 260 Query: 312 FVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAF-KDFEKRICVSTDVFGRGI 370 + S + + L A+ H + R + + ++ +T FG GI Sbjct: 261 YCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGI 320 Query: 371 DIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKE 414 D + I+ L + Y GRAGR G + F + + Sbjct: 321 DKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHD 364 >2WWY-A nrPDB Length = 591 Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 60/358 (16%), Positives = 125/358 (34%), Gaps = 22/358 (6%) Query: 65 KDFLLK---PELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 +DF ++ + + E +Q TI ++ G +V +G GK+ + L L Sbjct: 24 EDFPWSGKVKDILQNVFKL--EKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPAL 81 Query: 122 QQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNK 181 + +VIC L + + + + NK Sbjct: 82 C------SDGFTLVICPLISLMEDQLMVLKQLGISATMLN--ASSSKEHVKWVHAEMVNK 133 Query: 182 DTAPHIVVATPGRL-----KALVREKYIDLSHVKNFVIDECDKVLEE-LDMRRDVQE--I 233 ++ ++ TP ++ EK + +DE + D R D + I Sbjct: 134 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI 193 Query: 234 FRATPRDKQVMMFSATLSQEIRPICRRFL-QNPLEIFVDDEAKLTLHGLQQYYIKLEERE 292 + + ++ +AT + + ++ L F + L+ + E Sbjct: 194 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF 253 Query: 293 KNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAF 352 + + + II+ S + ++T L A H +++ E++ ++ + Sbjct: 254 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW 313 Query: 353 KDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFV 410 E ++ V+T FG GID + I++ ++ + Y GRAGR K I + Sbjct: 314 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYY 371 >2P6R-A nrPDB Length = 702 Score = 121 bits (303), Expect = 8e-28, Method: Composition-based stats. Identities = 63/394 (15%), Positives = 131/394 (33%), Gaps = 62/394 (15%) Query: 77 IIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVI 136 + + G E Q + + G ++L + GKT +L+ + + + + Sbjct: 18 LKEEGIEELFPPQAEAVEKVFSGKNLLLAMPTAAGKT---LLAEMAMVREAIKGGKSLYV 74 Query: 137 CNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLK 196 R LA + + ++ K ++ + G D E I+V T + Sbjct: 75 VPLRALAGEKYESFKKWEKI--GLRIGISTG------DYESRDEHLGDCDIIVTTSEKAD 126 Query: 197 ALVREKYIDLSHVKNFVIDECDKVLE---ELDMRRDVQEIFRATPRDKQVMMFSATLSQE 253 +L+R + + V V+DE +L+ + R + +V+ SAT Sbjct: 127 SLIRNRASWIKAVSCLVVDEIH-LLDSEKRGATLEILVTKMRRMNKALRVIGLSATAPNV 185 Query: 254 IRPICRRFLQNPLEIF----VDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDD--LEFN 307 +L + V + G + + + K +L+++ E Sbjct: 186 TE--IAEWLDADYYVSDWRPVPLVEGVLCEGTLELFDGAFSTSRRVKFEELVEECVAENG 243 Query: 308 QVIIFVKSTTRANELTKLLNASNFP------------------------------AITVH 337 V++F + A + L+A A H Sbjct: 244 GVLVFESTRRGAEKTAVKLSAITAKYVENEGLEKAILEENEGEMSRKLAECVRKGAAFHH 303 Query: 338 GHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAI----NYDLTN---EADQY 390 + +R AF+ ++ V+T G+++ + + +D + + +Y Sbjct: 304 AGLLNGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPARRVIVRSLYRFDGYSKRIKVSEY 363 Query: 391 LHRVGRAGRFGT--KGLAISFVSSKEDEEVLAKI 422 GRAGR G +G AI V ++ E + + Sbjct: 364 KQMAGRAGRPGMDERGEAIIIVGKRDREIAVKRY 397 >2ZJ8-A nrPDB Length = 720 Score = 120 bits (301), Expect = 1e-27, Method: Composition-based stats. Identities = 68/408 (16%), Positives = 140/408 (34%), Gaps = 65/408 (15%) Query: 65 KDFLLKPELSRAIIDCGFEHPSEVQQHTI-PQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 + + + + + G E Q + + G + L + GKT + ++ + + Sbjct: 4 DELRVDERIKSTLKERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAMVHR 63 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 + G V I + LA + E+ + K ++ A+ G + Sbjct: 64 ILTQGG--KAVYIVPLKALAEEKFQEFQDWEKI--GLRVAMATGDYDSKDEWLGK----- 114 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 I++AT + +L+R + VK V DE ++ D ++ I Q+ Sbjct: 115 -YDIIIATAEKFDSLLRHGSSWIKDVKILVADEIH-LIGSRDRGATLEVILAHMLGKAQI 172 Query: 244 MMFSATL--SQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEER--EKNRKLAQ 299 + SAT+ +E+ L L + KL Q ++ E+ ++ + Sbjct: 173 IGLSATIGNPEELAEW----LNAELIVSDWRPVKLRRGVFYQGFVTWEDGSIDRFSSWEE 228 Query: 300 LLDD--LEFNQVIIFVKSTTRANELTKLLNASNFPAIT---------------------- 335 L+ D + +IFV +A + L+ +T Sbjct: 229 LVYDAIRKKKGALIFVNMRRKAERVALELSKKVKSLLTKPEIRALNELADSLEENPTNEK 288 Query: 336 -----------VHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAI----- 379 H + ++ER+ + F+ + V+T GI+ + I Sbjct: 289 LAKAIRGGVAFHHAGLGRDERVLVEENFRKGIIKAVVATPTLSAGINTPAFRVIIRDIWR 348 Query: 380 --NYDLTNEADQYLHR-VGRAGR--FGTKGLAISFVSSKEDEEVLAKI 422 ++ + +H+ +GRAGR + G I +S + EV+ Sbjct: 349 YSDFGMERIPIIEVHQMLGRAGRPKYDEVGEGIIVSTSDDPREVMNHY 396 >2VA8-A nrPDB Length = 715 Score = 118 bits (297), Expect = 4e-27, Method: Composition-based stats. Identities = 74/420 (17%), Positives = 137/420 (32%), Gaps = 74/420 (17%) Query: 65 KDFLLKPELSRAIIDCGFEHPSEVQQHTIP-QSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 +D L + I G + + Q + + G +L + +G GKT + + + Sbjct: 11 EDLKLPSNVIEIIKKRGIKKLNPPQTEAVKKGLLEGNRLLLTSPTGSGKTLIAEMGIISF 70 Query: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 L + + + R A + K A+ G D LKN D Sbjct: 71 L--LKNGGKAIYVTPLR--ALTNEKYLTFKDWELIGFKVAMTSG--DYDTDDAWLKNYD- 123 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 I++ T +L +L R + L+ V FV+DE L + + V+ + + + + Sbjct: 124 ---IIITTYEKLDSLWRHRPEWLNEVNYFVLDELHY-LNDPERGPVVESVTIR-AKRRNL 178 Query: 244 MMFSATLS--QEIRPI--CRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNR---- 295 + SAT+S ++I N + + + ++Y + ++ + Sbjct: 179 LALSATISNYKQIAKWLGAEPVATNWRPVPLIEGVIYPERKKKEYNVIFKDNTTKKVHGD 238 Query: 296 ---KLAQLLDDLEFNQVIIFVKSTTRANELT----------------------------- 323 L + QV++F S A Sbjct: 239 DAIIAYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDENALSEILKQLDDIEE 298 Query: 324 -----KLLNASNFP--AITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERIN 376 K L S H + + R + F+ + ++ V+T G+++ Sbjct: 299 GGSDEKELLKSLISKGVAYHHAGLSKALRDLIEEGFRQRKIKVIVATPTLAAGVNLPART 358 Query: 377 LAI--NYDLTNEADQYLHRV---------GRAGR--FGTKGLAISFVSSKED-EEVLAKI 422 + I Y + Y + GRAGR F G +I V KED + V K Sbjct: 359 VIIGDIYRFNKKIAGYYDEIPIMEYKQMSGRAGRPGFDQIGESIVVVRDKEDVDRVFKKY 418 >5TNU-A nrPDB Length = 459 Score = 116 bits (292), Expect = 1e-26, Method: Composition-based stats. Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 5/129 (3%) Query: 271 DDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASN 330 + + L + I + + K KL ++L + + ++I+F + T A ++K Sbjct: 309 KEAREALLAWHESLNIAVNSQSKIEKLREILQEYKNEKIIVFTRDTQMAYRISKTFL--- 365 Query: 331 FPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQY 390 P +T ER + F+D E R+ V++ VF G+D+ LAI Q+ Sbjct: 366 IPVVTYKTDKD--EREEILQKFRDGEYRVIVASTVFDEGVDVPDATLAIVMGGYGTKRQF 423 Query: 391 LHRVGRAGR 399 L R+GR R Sbjct: 424 LQRLGRILR 432 >2FWR-A nrPDB Length = 472 Score = 111 bits (278), Expect = 5e-25, Method: Composition-based stats. Identities = 66/372 (17%), Positives = 130/372 (34%), Gaps = 72/372 (19%) Query: 89 QQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQ--- 145 Q+ + + + +G GKT V + + + P +++ LA Q Sbjct: 98 QEKALERWLVDKRGCIVLPTGSGKTHVAMAAINELSTPT------LIVVPTLALAEQWKE 151 Query: 146 ---IRNE--YLRFSKYMPDVKTAVFYGGTPISKDAELLKNK-----------------DT 183 I E FS + ++K +AE L N+ Sbjct: 152 RLGIFGEEYVGEFSGRIKELKPLTVSTYDSAYVNAEKLGNRFMLLIFDEVHHLPAESYVQ 211 Query: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDEC----------DKVLEELDMRRDVQEI 233 + +A P RL + ++ ++ E D + + + ++ I Sbjct: 212 IAQMSIA-PFRLGL---TATFEREDGRHEILKEVVGGKVFELFPDSLAGKHLAKYTIKRI 267 Query: 234 FRATPRDKQVMMFSATLSQEIRPICRRFLQ------------NPLEIFVD---DEAKLTL 278 F D++V ++ + ++FL+ N + + + Sbjct: 268 FVPLAEDERVEY------EKREKVYKQFLRARGITLRRAEDFNKIVMASGYDERAYEALR 321 Query: 279 HGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHG 338 + I + K RKL ++L+ +++IIF + ++K+ PAIT Sbjct: 322 AWEEARRIAFNSKNKIRKLREILERHRKDKIIIFTRHNELVYRISKVFL---IPAIT--H 376 Query: 339 HMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAG 398 +EER + F+ R VS+ V GID+ N+ + + A +Y+ R+GR Sbjct: 377 RTSREEREEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREYIQRLGRIL 436 Query: 399 RFGT-KGLAISF 409 R K A+ + Sbjct: 437 RPSKGKKEAVLY 448 >1GM5-A nrPDB Length = 780 Score = 103 bits (256), Expect = 2e-22, Method: Composition-based stats. Identities = 73/351 (20%), Positives = 130/351 (37%), Gaps = 44/351 (12%) Query: 84 HPSEVQQHTIPQSIHGT------DVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVIC 137 + Q+ + + + L Q G GKT V L+ L + + Sbjct: 368 KLTNAQKRAHQEIRNDMISEKPMNRLLQGDVGSGKTVVAQLAILDNYE---AGFQTAFMV 424 Query: 138 NARELAYQ-IRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTA-PHIVVATPGRL 195 LA Q R FSK+ ++ A+ G T S+ ++ +V+ T Sbjct: 425 PTSILAIQHYRRTVESFSKF--NIHVALLIGATTPSEKEKIKSGLRNGQIDVVIGT---- 478 Query: 196 KALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSAT-LSQEI 254 AL++E + ++ +IDE + +E + ++ SAT + Sbjct: 479 HALIQED-VHFKNLGLVIIDEQHR------FGVKQREALMNKGKMVDTLVMSATPIP--- 528 Query: 255 RPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEE-REKNRKLAQLLDDLEFNQV-IIF 312 R + F + L++ V DE +Q + ++ E + Q + + Q I++ Sbjct: 529 RSMALAFYGD-LDVTVIDEMPPGRKEVQTMLVPMDRVNEVYEFVRQ--EVMRGGQAFIVY 585 Query: 313 VK-------STTRANELTKLLNASNFP---AITVHGHMKQEERIARYKAFKDFEKRICVS 362 + A E+ + L+ FP +HG + QEE+ F + I VS Sbjct: 586 PLIEESDKLNVKSAVEMYEYLSKEVFPEFKLGLMHGRLSQEEKDRVMLEFAEGRYDILVS 645 Query: 363 TDVFGRGIDIERINLAINYDLTNEADQYLHRV-GRAGRFGTKGLAISFVSS 412 T V GID+ R N+ + + LH++ GR GR G + V Sbjct: 646 TTVIEVGIDVPRANVMVIENPERFGLAQLHQLRGRVGRGGQEAYCFLVVGD 696 >5AGA-A nrPDB Length = 830 Score = 96.2 bits (238), Expect = 2e-20, Method: Composition-based stats. Identities = 72/449 (16%), Positives = 134/449 (29%), Gaps = 107/449 (23%) Query: 68 LLKPELSRAIIDCGFEHPSEVQQHTI--PQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLD 125 L + G + E Q + Q + G +++ A + GKT V L L+++ Sbjct: 11 GLPKAVLEKYHSFGVKKMFEWQAECLLLGQVLEGKNLVYSAPTSAGKTLVAELLILKRVL 70 Query: 126 PVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAP 185 + + I +A + + YL+ +K + G T S+ L Sbjct: 71 EMRK--KALFILPFVSVAKE-KKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSL------- 120 Query: 186 HIVVATPGR----LKALVREKYIDLSHVKNFVIDECDKVLEEL-DMRRDV---------- 230 I V T R + L+ E +DL + V+DE + + ++ Sbjct: 121 DIAVCTIERANGLINRLIEENKMDL--LGMVVVDELHMLGDSHRGYLLELLLTKICYITR 178 Query: 231 ------QEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQY 284 ++ + Q++ SATL + +L L L Sbjct: 179 KSASCQADLASSLSNAVQIVGMSATLPN--LELVASWLNAELYHTDFRPVPLLESVKVGN 236 Query: 285 YIKLEEREKNRKLAQLLDDL---------------EFNQVIIFVKSTTRANELTKLLNAS 329 I + R+ +L + + V++F S +L ++ Sbjct: 237 SIYDSSMKLVREFEPMLQVKGDEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIARE 296 Query: 330 NFP-------------------------------------------------AITVHGHM 340 + H + Sbjct: 297 FYNLHHQAEGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGL 356 Query: 341 KQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAI---NYDL-TNEADQYLHRVGR 396 EER AF+ R+ +T G+++ + I + + Y VGR Sbjct: 357 TFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGR 416 Query: 397 AGRFG--TKGLAISFVSSKEDEEVLAKIQ 423 AGR G T G +I + E + +A +Q Sbjct: 417 AGRKGVDTVGESILICKNSEKSKGIALLQ 445 >1WP9-A nrPDB Length = 494 Score = 94.7 bits (234), Expect = 7e-20, Method: Composition-based stats. Identities = 37/166 (22%), Positives = 63/166 (37%), Gaps = 13/166 (7%) Query: 267 EIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQL----LDDLEFNQVIIFVKSTTRANEL 322 EIF D K + L Q + K KL ++ L + +++I+F A ++ Sbjct: 318 EIFSDKRMKKAISLLVQAKEIGLDHPKMDKLKEIIREQLQRKQNSKIIVFTNYRETAKKI 377 Query: 323 TKLLNASNFPAITVHG--------HMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIER 374 L A G + Q E+ F E + V+T V G+D+ Sbjct: 378 VNELVKDGIKAKRFVGQASKENDRGLSQREQKLILDEFARGEFNVLVATSVGEEGLDVPE 437 Query: 375 INLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLA 420 ++L + Y+ A + + R GR GR G I ++ +E Sbjct: 438 VDLVVFYEPVPSAIRSIQRRGRTGRH-MPGRVIILMAKGTRDEAYY 482 Score = 59.6 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 27/133 (20%), Positives = 49/133 (36%), Gaps = 9/133 (6%) Query: 88 VQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPG-EVAVVVICNARELAYQI 146 + Q I T+ L +GLGKT +++ + + V+++ + L Q Sbjct: 12 IYQEVIYAKCKETNCLIVLPTGLGKT---LIAMMIAEYRLTKYGGKVLMLAPTKPLVLQ- 67 Query: 147 RNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDL 206 E R +P K G + ++ ++VATP ++ + I L Sbjct: 68 HAESFRRLFNLPPEKIVALTGEKSPEERSKAWARAK----VIVATPQTIENDLLAGRISL 123 Query: 207 SHVKNFVIDECDK 219 V V DE + Sbjct: 124 EDVSLIVFDEAHR 136 >6C90-A nrPDB Length = 734 Score = 88.5 bits (218), Expect = 5e-18, Method: Composition-based stats. Identities = 69/460 (15%), Positives = 125/460 (27%), Gaps = 117/460 (25%) Query: 67 FLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDP 126 LKP + +A + F Q+ I + VL A + GKT + L Sbjct: 56 LPLKPRVGKAAKEYPF-ILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALRE 114 Query: 127 VPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPH 186 V+ + L+ Q E Y + G I+ A Sbjct: 115 KQ---RVIFTSPIKALSNQKYREM-----YEEFQDVGLMTGDVTINPTASC--------- 157 Query: 187 IVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLE-ELDMRRDVQEIFRATPRDKQVMM 245 +V T L++++ + V + DE + + E + + I P + + Sbjct: 158 -LVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIIL--LPDNVHYVF 214 Query: 246 FSATLSQEIRPICR---------------RFLQNPLEIFVDDEAKLTLHGLQQYYIKLEE 290 SAT+ R + PL+ ++ LH + E Sbjct: 215 LSATIPNA-RQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFRE 273 Query: 291 REKNRKLAQLLD------------------------------DLEFNQVIIFVKSTTRAN 320 N + L D + F VIIF S Sbjct: 274 DNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCE 333 Query: 321 ELTKLLNASNFPA---------------------------------------ITVHGHMK 341 + +F HG + Sbjct: 334 AYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLL 393 Query: 342 QEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAI----NYDLTN----EADQYLHR 393 + F + + +T+ F GI++ + +D + + +Y+ Sbjct: 394 PILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQM 453 Query: 394 VGRAGRFGT--KGLAISFVSSKEDEEVLAKIQERFDVKIA 431 GRAGR G +G+ I V K + ++ + + Sbjct: 454 SGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLN 493 >3P4X-A nrPDB Length = 413 Score = 83.1 bits (204), Expect = 3e-16, Method: Composition-based stats. Identities = 60/333 (18%), Positives = 112/333 (33%), Gaps = 47/333 (14%) Query: 96 SIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSK 155 + G A +G+GKT F + L ++ L Q + + Sbjct: 32 IVQGKSFTMVAPTGVGKT-TFG--MMTALWLARKGKKSALVFPTVTLVKQTLERLQKLAD 88 Query: 156 YMPDVKTAVFYGGTPISKDAELLKNKDTAP-HIVV-----ATPGRLKALVREKYIDLSHV 209 VK FY + + K+ + HI+V + R K + Sbjct: 89 --EKVKIFGFYSSMKKEEKEKFEKSFEEDDYHILVFSTQFVSKNREKLSQKRFDFVFVDD 146 Query: 210 KNFVIDEC---DKVLEELDM-RRDVQEIFRAT--------PRDKQ---VMMFSATL-SQE 253 + V+ D +L + + +++ F P++ + +++ SAT + Sbjct: 147 VDAVLKASRNIDTLLMMVGIPEEIIRKAFSTIKQGKIYERPKNLKPGILVVSSATAKPRG 206 Query: 254 IRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFV 313 IRP+ R L N F + I +EK +L ++ + ++IF Sbjct: 207 IRPLLFRDLLN----FTVGRLVSVARNITHVRISSRSKEKLVELLEIFR----DGILIFA 258 Query: 314 KSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDV----FGRG 369 ++ EL + L F E ++ FK + I + RG Sbjct: 259 QTEEEGKELYEYLKRFKFNVGE-----TWSEFEKNFEDFKVGKINILIGVQAYYGKLTRG 313 Query: 370 IDIE-RINLAINYDLTNEAD--QYLHRVGRAGR 399 +D+ RI I + + D Y+ GR+ R Sbjct: 314 VDLPERIKYVIFWGTPSGPDVYTYIQASGRSSR 346 >2NMV-A nrPDB Length = 661 Score = 79.2 bits (194), Expect = 4e-15, Method: Composition-based stats. Identities = 43/270 (15%), Positives = 90/270 (33%), Gaps = 52/270 (19%) Query: 191 TPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVM------ 244 TP L + + V+DE + V+ +F KQV+ Sbjct: 321 TPYTLLDYFPDDF-------MIVVDESHVTI------PQVRGMFNGDQARKQVLVDHGFR 367 Query: 245 MFSA--TLSQEIRPICRRFLQNPLEIFVDDEA---KLTLHGLQQ-------YYIKLEERE 292 + SA + + N + + + T ++Q ++ R Sbjct: 368 LPSALDNRPLRFEEF-EKHMHNIVYVSATPGPYEIEHTDEMVEQIIRPTGLLDPLIDVRP 426 Query: 293 KNRKLAQLLDDLE-----FNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIA 347 ++ L+ +++ +V++ + + +LT L +H +K ERI Sbjct: 427 IEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIKTLERIE 486 Query: 348 RYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTN-----EADQYLHRVGRAGRFGT 402 + + + + V ++ G+DI ++L D + +GRA R Sbjct: 487 IIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNA- 545 Query: 403 KGLAISFVSSKEDEEVLAKIQERFDVKIAE 432 +G I + KI + ++ I E Sbjct: 546 EGRVIMYAD---------KITKSMEIAINE 566 Score = 32.2 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 10/71 (14%) Query: 85 PSEVQQ--HTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNAREL 142 P +++ I + +L +G GKT F +S L + P +VI + + L Sbjct: 18 PKAIEKLVKGIQEGKKHQTLLGA--TGTGKT--FTVSNLIKEVNKP----TLVIAHNKTL 69 Query: 143 AYQIRNEYLRF 153 A Q+ +E+ F Sbjct: 70 AGQLYSEFKEF 80 >1D9Z-A nrPDB Length = 657 Score = 78.9 bits (193), Expect = 4e-15, Method: Composition-based stats. Identities = 48/289 (16%), Positives = 89/289 (30%), Gaps = 69/289 (23%) Query: 191 TPGRLKALVREKYIDLSHVKNFVIDECD-----------------KVLEELDMRRDVQEI 233 TP L + ++ ++DE +VL + R Sbjct: 320 TPYTLLDYFPDDFL-------IIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALD 372 Query: 234 FRATP------RDKQVMMFSAT--------LSQEIRPICRRF-LQNPLEIFVDDEAKLTL 278 R + Q++ SAT + I R L +P I V Sbjct: 373 NRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDP-TIDVRPTKGQID 431 Query: 279 HGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHG 338 + + ++E E+ ++ + A +LT L + +H Sbjct: 432 DLIGEIRERVERNER---------------TLVTTLTKKMAEDLTDYLKEAGIKVAYLHS 476 Query: 339 HMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTN-----EADQYLHR 393 +K ERI + + + + V ++ G+DI ++L D + Sbjct: 477 EIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQT 536 Query: 394 VGRAGRFGTKGLAISFVSS-KEDEEVL-------AKIQERFDVKIAEFP 434 +GRA R G I + + + E+ IQE ++ K P Sbjct: 537 IGRAARNAN-GHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVP 584 Score = 30.7 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 19/46 (41%), Gaps = 6/46 (13%) Query: 108 SGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRF 153 +G GKT Q P +VI + + LA Q+ +E F Sbjct: 41 TGTGKTFTISNVIAQVNKPT------LVIAHNKTLAGQLYSELKEF 80 >1C4O-A nrPDB Length = 664 Score = 73.1 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 44/265 (16%), Positives = 79/265 (29%), Gaps = 52/265 (19%) Query: 192 PGRLKALVREKYIDLSHVKNFVIDECD-----------------KVLEELDMRRDVQEIF 234 P L E ++ +DE K L + R Sbjct: 316 PYTLLDYFPEDFLVF-------LDESHVTVPQLQGMYRGDYARKKTLVDYGFRLPSALDN 368 Query: 235 RATP------RDKQVMMFSATL-SQEIR---PICRRFLQNPLEIFVDDEAKLTLHGLQQY 284 R R QV+ SAT E+ + + ++ + K T + + Sbjct: 369 RPLRFEEFLERVSQVVFVSATPGPFELAHSGRVVEQIIRPTGLLDPLVRVKPTENQILDL 428 Query: 285 YIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEE 344 + ER + ++ V + A ELT L A +H + + Sbjct: 429 MEGIRER-----------AARGERTLVTVLTVRMAEELTSFLVEHGIRARYLHHELDAFK 477 Query: 345 RIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTN-----EADQYLHRVGRAGR 399 R A + + V ++ G+DI ++L D + +GRA R Sbjct: 478 RQALIRDLRLGHYDCLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAAR 537 Query: 400 FGTKGLAISFVSSKEDEEVLAKIQE 424 G + + + E + I+E Sbjct: 538 NAR-GE-VWLYADRVSEAMQRAIEE 560 Score = 36.9 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 45/147 (30%), Gaps = 35/147 (23%) Query: 81 GFEHPSEV--QQHTIPQSIHG-TD------VLCQAKSGLGKTAVFVLSTLQQLDPVPGEV 131 + PS Q I + D +L +G GKT + ++ G Sbjct: 3 RYRGPSPKGDQPKAIAGLVEALRDGERFVTLLGA--TGTGKTVT-----MAKVIEALGRP 55 Query: 132 AVVVICNARELAYQIRNEYLR---------FSKYMPDVKTAVFYGGTPISKDAELLKNKD 182 +V+ + LA Q+ E+ F Y + + G KD + K+ Sbjct: 56 -ALVLAPNKILAAQLAAEFRELFPENAVEYFISYYDYYQPEAYVPG----KDLYIEKDAS 110 Query: 183 TAPHIVVATPGRLKALVREKYIDLSHV 209 P I RL+ + V Sbjct: 111 INPEI-----ERLRHSTTRSLLTRRDV 132 >4XGT-A nrPDB Length = 993 Score = 71.5 bits (174), Expect = 6e-13, Method: Composition-based stats. Identities = 78/514 (15%), Positives = 150/514 (29%), Gaps = 132/514 (25%) Query: 19 IQIDASKAAEAGE-TGAATSA-TEGDNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRA 76 I DA + AE+ E TGA A TEG++ + + + + + Sbjct: 1 IMTDAFQTAESREVTGAQGFAPTEGESIVLSHNIQHQVALPPDLDYEYIPLSEHKPPAEP 60 Query: 77 IIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVI 136 F Q ++ VL A + GKT V + Q L V+ Sbjct: 61 ARTYSF-KLDPFQALSVASIEREESVLVSAHTSAGKTVVAEYAIAQCLK---KNQRVIYT 116 Query: 137 CNARELAYQIRNEYL-RFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRL 195 + L+ Q ++ F + G I+ A +V T L Sbjct: 117 SPIKALSNQKYRDFQAEFGD------VGLMTGDVTINPTASC----------LVMTTEIL 160 Query: 196 KALVREKYIDLSHVKNFVIDECDKVLEEL-DMRRDVQEIFRATPRDKQVMMFSATLSQEI 254 ++++ + V V DE + +++ + + I P + + SAT+ Sbjct: 161 RSMLYRGSEIMREVAWVVFDEIHYMRDKIRGVVWEETIIL--LPDKVRYVFLSATIPNAF 218 Query: 255 R--PICRRF----------------LQNPLE--------IFVDDEAKLTLHGLQQYYIKL 288 + + LQN + VD++ + Q + Sbjct: 219 QFAEWIAKIHRQACHVVYTDFRPTPLQNYFFPAGGKGILLIVDEKGNFKENNFNQAMAMI 278 Query: 289 EEREKNR-------------------------------KLAQLLDDLEFNQVIIFVKSTT 317 EE++ K+ +++ F VI+F S Sbjct: 279 EEKKGTDSNDWSAKQKGKGKNKKTNKGGEAADEKADIAKIIKMILKKNFQPVIVFNFSKR 338 Query: 318 RANELTKLLNASNFPA---------------------------------------ITVHG 338 ++ ++ F A H Sbjct: 339 ECEQMALASSSMKFNAPDEENMVNKVFENALASLSEDDKNLPQISNILPLLRKGIGVHHS 398 Query: 339 HMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAI----NYDL----TNEADQY 390 + + F++ ++ +T+ F G+++ + +D + +Y Sbjct: 399 GLLPILKETIEILFQEGLIKVLFATETFSIGLNMPARTVVFTQVTKWDGQQRRPLTSSEY 458 Query: 391 LHRVGRAGRFGT--KGLAISFVSSKEDEEVLAKI 422 + GRAGR G +G+ I V K + E I Sbjct: 459 IQMAGRAGRRGLDDRGIVIMMVDDKLEPETARAI 492 >4GL2-A nrPDB Length = 699 Score = 68.5 bits (166), Expect = 6e-12, Method: Composition-based stats. Identities = 30/127 (23%), Positives = 46/127 (36%), Gaps = 19/127 (14%) Query: 290 EREKNRKLA-----QLLDDLEFNQVIIFVKSTTRANELTKLLNASN----------FPAI 334 E EK KL Q E + IIF K+ A L++ + + Sbjct: 379 ENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIG 438 Query: 335 TVHGH----MKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQY 390 H M Q E+ F+ + + ++T V G+DI+ N+ I Y L Sbjct: 439 AGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAM 498 Query: 391 LHRVGRA 397 + GRA Sbjct: 499 VQARGRA 505 Score = 50.4 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 30/142 (21%), Positives = 49/142 (34%), Gaps = 15/142 (10%) Query: 87 EVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEV---AVVVICNARELA 143 Q ++ G +++ +G GKT V V LD V+V+ N L Sbjct: 10 PYQMEVAQPALEGKNIIICLPTGCGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLV 69 Query: 144 YQIR-NEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATP----GRLKAL 198 Q+ E+ F K + G T + + I+++T L L Sbjct: 70 EQLFRKEFQPFLKKWY--RVIGLSGDTQLKISFP---EVVKSCDIIISTAQILENSLLNL 124 Query: 199 V--REKYIDLSHVKNFVIDECD 218 + + LS +IDEC Sbjct: 125 ENGEDAGVQLSDFSLIIIDECH 146 >5JBJ-A nrPDB Length = 680 Score = 68.1 bits (165), Expect = 7e-12, Method: Composition-based stats. Identities = 36/164 (21%), Positives = 57/164 (34%), Gaps = 25/164 (15%) Query: 252 QEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQV-- 309 ++ + RFL + L G Q+Y E + KL ++L + Sbjct: 320 RDTKDPTERFLA--TTFEENRATLQALAGDQRY-----ENPRLSKLEEILQEHFQPPGSS 372 Query: 310 --IIFVKSTTRANELTKLLNA------SNFPAITVHG--------HMKQEERIARYKAFK 353 I+F K+ A+ L L + A + G M Q E+ F+ Sbjct: 373 RGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFR 432 Query: 354 DFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRA 397 E + ST V G+DI N+ + Y L + GRA Sbjct: 433 YGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRA 476 Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 43/134 (32%), Gaps = 10/134 (7%) Query: 89 QQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRN 148 Q + ++ G + + +G GKT V + L+ G V V+ N L Q Sbjct: 13 QLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGG-RVAVLVNKVHLVQQHLE 71 Query: 149 EYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATP----GRLKALVREKYI 204 F K G + +V+ T L + E + Sbjct: 72 --KEFHVLRDAFKVTAVSGDSSHK---CFFGQLAKGSDVVICTAQILQNALLSGEEEARV 126 Query: 205 DLSHVKNFVIDECD 218 +L+ VIDEC Sbjct: 127 ELTDFSLLVIDECH 140 >6G19-A nrPDB Length = 696 Score = 67.7 bits (164), Expect = 9e-12, Method: Composition-based stats. Identities = 27/119 (22%), Positives = 44/119 (36%), Gaps = 14/119 (11%) Query: 293 KNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASN----------FPAITVHGH--- 339 +N L Q E ++ IIF K+ L++ + + H Sbjct: 381 RNTILEQFTRSEESSRGIIFTKTRQSTYALSQWIMENAKFAEVGVKAHHLIGAGHSSEVK 440 Query: 340 -MKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRA 397 M Q E+ F+ E + ++T V G+DI+ N+ I Y L + GRA Sbjct: 441 PMTQTEQKEVISKFRTGEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA 499 Score = 46.5 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 52/142 (36%), Gaps = 15/142 (10%) Query: 87 EVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEV---AVVVICNARELA 143 Q ++ G +++ +G GKT V V T LD V+V+ N LA Sbjct: 5 PYQMEVAQPALDGKNIIICLPTGSGKTRVAVYITKDHLDKKKQASESGKVIVLVNKVMLA 64 Query: 144 YQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAEL-LKNKDTAPHIVVATP----GRLKAL 198 Q+ + ++ P +K G ++ + ++++T L L Sbjct: 65 EQLFRK-----EFNPYLKKWYRIIGLSGDTQLKISFPEVVKSYDVIISTAQILENSLLNL 119 Query: 199 V--REKYIDLSHVKNFVIDECD 218 + + LS +IDEC Sbjct: 120 ESGDDDGVQLSDFSLIIIDECH 141 >5VHD-D nrPDB Length = 870 Score = 67.7 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 72/464 (15%), Positives = 137/464 (29%), Gaps = 105/464 (22%) Query: 65 KDFLLKPELSRAIIDCGFEHPSE---VQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 +D K R I F +Q+ + + + ++G GKT L Sbjct: 39 EDLQKKKTDLRYIEMQRFREKLPSYGMQKELVNMIDNHQVTVISGETGCGKTTQVTQFIL 98 Query: 122 QQLDPVPGEVAVVVIC--NARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELL- 178 A ++C R A + + G L Sbjct: 99 DNYIERGKGSACRIVCTQPRRISAISVAERVAA-------ERAESCGNGNSTGYQIRLQS 151 Query: 179 KNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATP 238 + I+ T G + ++ LS V + V+DE + + D+ V + + Sbjct: 152 RLPRKQGSILYCTTGIILQWLQSDP-HLSSVSHIVLDEIHERNLQSDVLMTVVKDLLSYR 210 Query: 239 RDKQVMMFSAT----------------------LS----------QEIR----------P 256 D +V++ SAT ++IR Sbjct: 211 PDLKVVLMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEKIRYVPEQKEHRSQ 270 Query: 257 ICRRFLQN--------PLEIFVDDEAKLTLHGLQQYY-------IKLEEREKNRK----- 296 + F+Q E + L L+Q Y +++ + EK Sbjct: 271 FKKGFMQGHVNRQEKYYYEAIYKERWPGYLRELRQRYSASTVDVVEMMDDEKVDLNLIAA 330 Query: 297 -LAQLLDDLEFNQVIIFV----KSTTRANELTK--LLNASNFPAITVHGHMKQEERIARY 349 + ++ + E +++F+ +T + L + + F I +H M + + Sbjct: 331 LIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFIIIPLHSLMPTVNQTQVF 390 Query: 350 KAFKDFEKRICVSTDVFGRGIDIERINLAI--------NYDLTNEA----------DQYL 391 K ++I ++T++ I I+ + I ++D N Sbjct: 391 KRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAK 450 Query: 392 HRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQ--ERFDVKIAEF 433 R GRAGR G +S +L Q E + E Sbjct: 451 QRKGRAGRV-QPGHCYHLYNSL-RASLLDDYQLPEILRTPLEEL 492 >5JCF-A nrPDB Length = 701 Score = 64.2 bits (155), Expect = 9e-11, Method: Composition-based stats. Identities = 37/172 (21%), Positives = 58/172 (33%), Gaps = 26/172 (15%) Query: 294 NRKLAQLLDDLEFNQVIIFVKSTTRANELTKL------LNASNFPAITVHGH-------- 339 L + E + IIF K+ A L A + G Sbjct: 387 RNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKP 446 Query: 340 MKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGR 399 M Q E+ F+ + ++T V G+DI+ N+ I Y L + GRA R Sbjct: 447 MTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA-R 505 Query: 400 FGTKGLAISFVS-----SKEDEEVLAK-IQERFDVKIAEFPEEGIDPSTYLN 445 A+ S +ED + + + + ++ E P E YLN Sbjct: 506 ADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEE-----YLN 552 Score = 41.1 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 52/139 (37%), Gaps = 14/139 (10%) Query: 89 QQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEV---AVVVICNARELAYQ 145 Q +++G +++ +G GKT V V T LD V+V+ N L Q Sbjct: 12 QMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQ 71 Query: 146 -IRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATP----GRLKALVR 200 +R E+ F K+ + G + + + + +++ T L Sbjct: 72 HLRKEFNPFLKHWY--QVIGLSGDSELKISFPEVVKRY---DVIICTAQILENSLLNATE 126 Query: 201 EK-YIDLSHVKNFVIDECD 218 E + LS +ID+C Sbjct: 127 EDESVRLSDFSLIIIDQCH 145 >3TBK-A nrPDB Length = 555 Score = 63.8 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 41/205 (20%), Positives = 71/205 (34%), Gaps = 28/205 (13%) Query: 248 ATLSQEIRPICRRFLQNPLEIFVDDEAKLTLH-GLQQYYIKLEEREKNRKLAQLLDDLEF 306 A + R + RRF + E+ + L+ Y+ L+E Sbjct: 339 AAFDETERELTRRFEEKLEELEKVSRDPSNENPKLRDLYLVLQEE---------YHLKPE 389 Query: 307 NQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIA------------RYKAFK- 353 + I+FVK+ + L K + + + G + R +AF+ Sbjct: 390 TKTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGRTNRATGMTLPAQKCVLEAFRA 449 Query: 354 DFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSK 413 + I ++T V GIDI NL I Y+ + + GR GR SS Sbjct: 450 SGDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGR-GRA-RDSKCFLLTSSA 507 Query: 414 E--DEEVLAKIQER-FDVKIAEFPE 435 + ++E I+E+ + I Sbjct: 508 DVIEKEKANMIKEKIMNESILRLQT 532 Score = 54.6 bits (130), Expect = 8e-08, Method: Composition-based stats. Identities = 41/196 (20%), Positives = 68/196 (34%), Gaps = 28/196 (14%) Query: 84 HPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVP-GEVAVVVICNAREL 142 P Q + G + + A +G GKT V +L L P G+ VV Sbjct: 4 KPRNYQLELALPAKKGKNTIICAPTGCGKTFVSLLICEHHLKKFPCGQKGKVVF-----F 58 Query: 143 AYQI---RNEYLRFSKYMPDV--KTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKA 197 A QI + FS+Y + A G T D+ +++ I++ TP L Sbjct: 59 ANQIPVYEQQATVFSRYFERLGYNIASISGATS---DSVSVQHIIEDNDIIILTPQILVN 115 Query: 198 LVREKYI-DLSHVKNFVIDECDKVLEELDMRRDVQEIF-RATPRDK----QVMMFSA--- 248 + I LS + DEC + + + + QV+ +A Sbjct: 116 NLNNGAIPSLSVFTLMIFDECHNTSKNHPYNQIMFRYLDHKLGESRDPLPQVVGLTASVG 175 Query: 249 -----TLSQEIRPICR 259 T + ++ IC+ Sbjct: 176 VGDAKTAEEAMQHICK 191 >5GM6-Y nrPDB Length = 876 Score = 62.7 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 47/380 (12%), Positives = 117/380 (30%), Gaps = 64/380 (16%) Query: 91 HTIPQSIHGTDVLCQAKSGLGKTAVFVLS--TLQQLDPVPGEVAVVVICNARELAYQIRN 148 + + ++ ++G GKT L ++ G++ + + R A + Sbjct: 231 ELLQEIKKNQVLIIMGETGSGKTT--QLPQYLVEDGFTDQGKLQIAITQPRRVAAT---S 285 Query: 149 EYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIV-VATPGRLK-ALVREKYIDL 206 R + M G + ++ T G L + + + Sbjct: 286 VAARVADEMN------VVLGKEVGYQIRFEDKTTPNKTVLKYMTDGMLLREFLTDSKLSK 339 Query: 207 SHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPL 266 +IDE + D+ + + ++++ SAT+ + F P+ Sbjct: 340 YSC--IMIDEAHERTLATDILIGLLKDILPQRPTLKLLISSATM--NAKKFSEFFDNCPI 395 Query: 267 EIFVDDEAKLTLHGLQQY---YIKLEEREKNRKLAQLLDDLEFNQ----VIIFV------ 313 + +H Q YI + + +++F+ Sbjct: 396 FNVPGRRYPVDIHYTLQPEANYIHA-------AITTIFQIHTTQSLPGDILVFLTGQEEI 448 Query: 314 -KSTTRANELTKLL--NASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGI 370 ++ T+ E+ L ++ ++ QE+++ ++ + +++ ++T++ + Sbjct: 449 ERTKTKLEEIMSKLGSRTKQMIITPIYANLPQEQQLKIFQPTPENCRKVVLATNIAETSL 508 Query: 371 DIERINLAIN------------------YDLTNEADQYLHRVGRAGRFGTKGLAISFVSS 412 I+ I I+ + R GRAGR G G + Sbjct: 509 TIDGIRYVIDPGFVKENSYVPSTGMTQLLTVPCSRASVDQRAGRAGRVG-PGKCFRIFTK 567 Query: 413 KEDEEVLAKIQERFDVKIAE 432 L +++ +I Sbjct: 568 ---WSYLHELELMPKPEITR 584 >4ON9-A nrPDB Length = 580 Score = 61.9 bits (149), Expect = 5e-10, Method: Composition-based stats. Identities = 46/252 (18%), Positives = 80/252 (31%), Gaps = 47/252 (18%) Query: 212 FVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVD 271 +I E ++ + LD +D RA A + + + +RF + E+ Sbjct: 339 LIISEHARMKDALDYLKDFFSNVRA-----------AGFDEIEQDLTQRFEEKLQELESV 387 Query: 272 DEAKLTLHGLQQYYIKLEEREKNRKLAQLLDD----LEFNQVIIFVKSTTRANELTKLL- 326 E K L +L + I+FVK+ + L + Sbjct: 388 SRDPS------------NENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIE 435 Query: 327 ---NASNFPAITVHGHMKQEERIA--------RYKAFK-DFEKRICVSTDVFGRGIDIER 374 S + G K + AFK + I ++T V GIDI + Sbjct: 436 GNPKLSFLKPGILTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQ 495 Query: 375 INLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSK---EDEEVLAKIQERFDVKIA 431 NL I Y+ + + GR GR S+ E E++ ++ + I Sbjct: 496 CNLVILYEYVGNVIKMIQTRGR-GRA-RGSKCFLLTSNAGVIEKEQINMYKEKMMNDSIL 553 Query: 432 EFPEEGIDPSTY 443 D + + Sbjct: 554 RLQT--WDEAVF 563 Score = 52.3 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 33/147 (22%), Positives = 53/147 (36%), Gaps = 13/147 (8%) Query: 84 HPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELA 143 P Q ++ G + + A +G GKT V +L L P V+ A Sbjct: 29 KPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVF----FA 84 Query: 144 YQI---RNEYLRFSKY--MPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKAL 198 QI + FSKY + G T + E + + I++ TP L Sbjct: 85 NQIPVYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENN---DIIILTPQILVNN 141 Query: 199 VREKYI-DLSHVKNFVIDECDKVLEEL 224 +++ I LS + DEC ++ Sbjct: 142 LKKGTIPSLSIFTLMIFDECHNTSKQH 168 >4BPB-A nrPDB Length = 698 Score = 61.5 bits (148), Expect = 7e-10, Method: Composition-based stats. Identities = 46/254 (18%), Positives = 80/254 (31%), Gaps = 49/254 (19%) Query: 212 FVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVD 271 +I E ++ + LD +D RA A + + + +RF + E+ Sbjct: 323 LIISEHARMKDALDYLKDFFSNVRA-----------AGFDEIEQDLTQRFEEKLQELESV 371 Query: 272 DEAKLTLHGLQQYYIKLEEREKNRKLAQLLDD----LEFNQVIIFVKSTTRANELTKLL- 326 E K L +L + I+FVK+ + L + Sbjct: 372 SRDPS------------NENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIE 419 Query: 327 ---NASNFPAITVHGHMKQEERIA----------RYKAFK-DFEKRICVSTDVFGRGIDI 372 S + G K + AFK + I ++T V GIDI Sbjct: 420 GNPKLSFLKPGILTGRGKTNQNTFFGMTLPAQKCILDAFKASGDHNILIATSVADEGIDI 479 Query: 373 ERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSK---EDEEVLAKIQERFDVK 429 + NL I Y+ + + GR GR S+ E E++ ++ + Sbjct: 480 AQCNLVILYEYVGNVIKMIQTRGR-GRA-RGSKCFLLTSNAGVIEKEQINMYKEKMMNDS 537 Query: 430 IAEFPEEGIDPSTY 443 I D + + Sbjct: 538 ILRLQT--WDEAVF 549 Score = 53.1 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 52/262 (19%), Positives = 92/262 (35%), Gaps = 33/262 (12%) Query: 84 HPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELA 143 P Q ++ G + + A +G GKT V +L L P V+ A Sbjct: 13 KPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVF----FA 68 Query: 144 YQI---RNEYLRFSKY--MPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKAL 198 QI FSKY + G T + E + + I++ TP L Sbjct: 69 NQIPVYEQNKSVFSKYFERHGYRVTGISGATAENVPVEQIVENN---DIIILTPQILVNN 125 Query: 199 VREKYI-DLSHVKNFVIDECDKVLEELDMRRDV-----QEIFRATPRDKQVMMFSA---- 248 +++ I LS + DEC ++ + Q++ ++ QV+ +A Sbjct: 126 LKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASVGV 185 Query: 249 ----TLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDL 304 T + + IC+ L L+ V K L L+Q + + +K + + Sbjct: 186 GDAKTTDEALDYICK--LCASLDASVIATVKHNLEELEQ---VVYKPQKFFRKVESRISD 240 Query: 305 EFNQVIIFVKSTTRANELTKLL 326 +F +I + L K + Sbjct: 241 KFKYII--AQLMRDTESLAKRI 260 >6ID1-V nrPDB Length = 795 Score = 61.5 bits (148), Expect = 7e-10, Method: Composition-based stats. Identities = 68/447 (15%), Positives = 138/447 (30%), Gaps = 73/447 (16%) Query: 21 IDASKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDC 80 + AS +A + + +T +T + ++T AG + + F + P I+ Sbjct: 77 LKASHSAHSTHSAHSTHSTH--SAHSTHAGHAGHTSLPQCINPFTNLPHTPRYYD-ILKK 133 Query: 81 GFEHPS-EVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLS--TLQQLDPVPGEV-AVVVI 136 + P E + + + ++G GKT + ++ + +PG V Sbjct: 134 RLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTT--QIPQWCVEYMRSLPGPKRGVACT 191 Query: 137 CNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLK 196 R A + M + S +LK T G L Sbjct: 192 QPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILK---------YMTDGMLL 242 Query: 197 ALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRP 256 + L ++DE + D+ V + D +V++ SATL Sbjct: 243 REAMNDPL-LERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLD----- 296 Query: 257 ICRRFL--------------QNPLEIFVDDEAK---LTLHGLQQYYIKLEEREKNRKLAQ 299 +F +P+EIF E + L I + E E+ L Sbjct: 297 -AGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLF 355 Query: 300 LLDDLEFNQVIIFV-KSTTRANELTKLLNASNFPAITVHGHMKQEERIARYK----AFKD 354 L E ++ + ++L + + I ++ + +++ ++ ++ Sbjct: 356 LTGQEEIDEA---CKRIKREVDDLGPEV--GDIKIIPLYSTLPPQQQQRIFEPPPPKKQN 410 Query: 355 FEK--RICVSTDVFGRGIDIERINLAINYDLTN------------------EADQYLHRV 394 ++ VST++ + I+ + I+ R Sbjct: 411 GAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRA 470 Query: 395 GRAGRFGTKGLAISFVSSKEDEEVLAK 421 GRAGR G + K + + Sbjct: 471 GRAGRT-RPGKCFRLYTEKAYKTEMQD 496 >5N8S-A nrPDB Length = 944 Score = 60.8 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 60/412 (14%), Positives = 131/412 (31%), Gaps = 98/412 (23%) Query: 91 HTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNE- 149 I +L +G GKT + + D + A R + Q R Sbjct: 161 DIIQAVRENQVILIVGSTGCGKTT--QVPQILLDDAISRGCASSC----RIICTQPRRIS 214 Query: 150 YLRFSKYMPDVKTAVFYGGTPISKDAELL-KNKDTAPHIVVATPGRLKALVREKYIDLSH 208 + ++++ + G + L + I T G L ++ + + + Sbjct: 215 AIAIAEWVSYERCESL--GNSVGYQIRLESRKARERASITYCTTGVLLQQLQSDPL-MHN 271 Query: 209 VKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLE- 267 + ++DE + E D+ + ++ D +V++ SAT+ + + C F P+ Sbjct: 272 LSVLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSATVRE--QDFCDYFNNCPMFR 329 Query: 268 ----------IFVDDEAKLTLHGLQQYY-------------------------------- 285 ++++D T + Q++ Sbjct: 330 IEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNSYDS 389 Query: 286 -----------IKLEEREKNRKLAQLLDDLEFNQVI-IFVKSTTRANELTKLLNA----- 328 E+ + L + + E I +F+ + ++L +L+ Sbjct: 390 RVLDKLRLPESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPKTSK 449 Query: 329 -----SNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAI---- 379 + +H M+ E+ A ++ ++++ +ST + + I+ + I Sbjct: 450 GQRWRDHMAVFPLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGR 509 Query: 380 ----NYDLTNEA----------DQYLHRVGRAGRFGTKGLAISFVSS-KEDE 416 NYD+ R GRAGR G+ + S +ED Sbjct: 510 TKATNYDIETNIQSLDEVWVTKANTQQRRGRAGRV-RPGICYNLFSRAREDR 560 >6BOG-A nrPDB Length = 968 Score = 60.0 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 31/185 (16%), Positives = 60/185 (32%), Gaps = 18/185 (9%) Query: 225 DM-RRDVQEIFRATPRDKQVMM-FSATLS--QEIRPICRRFLQNPLEIFV-DDEAKLTLH 279 +R++ I P Q + S + + R L P I+ + T Sbjct: 427 GFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLY-PERIYQEFEGDNATWW 485 Query: 280 GLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNAS-NFPAITVHG 338 + L L +V++ A +L ++L A H Sbjct: 486 NF---------DPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHE 536 Query: 339 HMKQEERIARYKAFKDFE--KRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGR 396 M ER F + + ++ + +++ G + + + + +DL D R+GR Sbjct: 537 GMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGR 596 Query: 397 AGRFG 401 R G Sbjct: 597 LDRIG 601 >5I8Q-A nrPDB Length = 767 Score = 60.0 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 56/406 (13%), Positives = 122/406 (30%), Gaps = 59/406 (14%) Query: 77 IIDCGFEHPSEVQQHTIPQSIHGTDVLC-QAKSGLGKTAVFVLSTLQQLDPVP--GEVAV 133 I+ E P Q+ + ++ ++G GKT + D +P V Sbjct: 86 ILKIRRELPVHAQRDEFLKLYQNNQIMVFVGETGSGKTT--QIPQFVLFDEMPHLENTQV 143 Query: 134 VVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPG 193 R A + + + + +LK T G Sbjct: 144 ACTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFENKTSNKTILK---------YMTDG 194 Query: 194 RLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQE 253 L E + DLS ++DE + D+ + + D ++++ SATL + Sbjct: 195 MLLREAMEDH-DLSRYSCIILDEAHERTLATDILMGLLKQVVKRRPDLKIIIMSATL--D 251 Query: 254 IRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFV 313 R F PL + V + + R + Q+ E +++F+ Sbjct: 252 AEKFQRYFNDAPL-LAVPGRTYPVELYYTPEFQRDYLDSAIRTVLQIHATEEAGDILLFL 310 Query: 314 KSTTRANELTKLLNASN-----------FPAITVHGHMKQEERIARYK---AFKDFE--K 357 + + ++ ++G + ++ ++ + + Sbjct: 311 TGEDEIEDAVRKISLEGDQLVREEGCGPLSVYPLYGSLPPHQQQRIFEPAPESHNGRPGR 370 Query: 358 RICVSTDVFGRGIDIERINLAINYDL------------------TNEADQYLHRVGRAGR 399 ++ +ST++ + I+ I ++ R GRAGR Sbjct: 371 KVVISTNIAETSLTIDGIVYVVDPGFSKQKVYNPRIRVESLLVSPISKASAQQRAGRAGR 430 Query: 400 FGTKGLAISFVSSKEDEEVLAK------IQERFDVKIAEFPEEGID 439 G + + ++ L + ++ + E + GID Sbjct: 431 T-RPGKCFRLYTEEAFQKELIEQSYPEILRSNLSSTVLELKKLGID 475 >6FA9-A nrPDB Length = 655 Score = 59.6 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 52/378 (13%), Positives = 116/378 (30%), Gaps = 69/378 (18%) Query: 102 VLCQAKSGLGKTAVFVLS-TLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDV 160 ++ ++G GKT + L + G + R A + Sbjct: 50 LILVGETGSGKTT--QIPQYLHEAGYTKGNRKIACTQPRRVAAMSVAARVADEMGVRLGH 107 Query: 161 KTAVFYGGTPISKDAELLKNKDTAPHI--VVATPGRLKALVREKYIDLSHVKNFVIDECD 218 + + + +LK + +V +P DL+ +IDE Sbjct: 108 EVGYSIRFEDCTSEKTILKYMTDGMLLREMVTSP------------DLADYSCIMIDEAH 155 Query: 219 KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTL 278 + D+ + + + ++++ SATL F P+ V + Sbjct: 156 ERTVHTDILLALIKDLTRARPELRLIISSATL--NAEKFSAYFDDAPIF-NVPGR----V 208 Query: 279 HGLQQYYIKLEEREKNRK----LAQLLDDLEFNQVIIFV-------KSTTRANELTKLLN 327 H ++ YY E + Q+ +++F+ ++ R E+ + L Sbjct: 209 HPVEVYYTSAPESNYLEAALVTVFQIHATQPEGDILVFLTGQEEIERACERVEEIRRKLG 268 Query: 328 AS--NFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYD--- 382 A+ ++ +M E + ++ +++ ST++ + I+ I I+ Sbjct: 269 KRVPEIIALPIYSNMPSEMQAKIFEPTPPGARKVVFSTNIAETSLTIDGIVYVIDSGYVK 328 Query: 383 -----------------LTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQER 425 + R+GRAGR G + + Sbjct: 329 ENTFSPVGTTGQSTLAVVPCSRAAANQRMGRAGRV-KPGKCFRLYT-----------KYA 376 Query: 426 FDVKIAEFPEEGIDPSTY 443 + ++ E P I ++ Sbjct: 377 YLSEMDESPTPEIQRTSL 394 >6HEG-A nrPDB Length = 809 Score = 59.6 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 56/363 (15%), Positives = 126/363 (34%), Gaps = 55/363 (15%) Query: 93 IPQSIHGTD----VLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRN 148 +P+ + D VL A +G GK+ L P ++++ R A + Sbjct: 10 LPELLTALDCAPQVLLSAPTGAGKST--WLPLQLLAHPGING-KIILLEPRRLAARNVAQ 66 Query: 149 EYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSH 208 P L+ V T G L +++ +LS Sbjct: 67 RLAELLNEKPGDTVGYRMRAQNCVGPNTRLE---------VVTEGVLTRMIQRDP-ELSG 116 Query: 209 VKNFVIDECD-KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLE 267 V ++DE + L+ + ++ + D ++++ SATL + + + + P+ Sbjct: 117 VGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLDND--RLQQMLPEAPVV 174 Query: 268 IFVDDEAKLTLHGLQQYYIKLEEREKNR-----KLAQLLDDLEFNQVIIFV----KSTTR 318 I +++ Y+ L ++ A++L E +++F+ + Sbjct: 175 ISEGRSFP-----VERRYLPLPAHQRFDDAVAVATAEML-RQESGSLLLFLPGVGEIQRV 228 Query: 319 ANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLA 378 +L + + ++R A A +++ ++T++ + IE I L Sbjct: 229 QEQLASRIGSDVLLCPLYGALSLNDQRKAILPA-PQGMRKVVLATNIAETSLTIEGIRLV 287 Query: 379 IN--------YDLTN----------EADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLA 420 ++ +D R GRAGR G+++ ++ ++ E A Sbjct: 288 VDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRL-EPGISLHLIAKEQAERAAA 346 Query: 421 KIQ 423 + + Sbjct: 347 QSE 349 >5D0U-A nrPDB Length = 714 Score = 59.2 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 59/395 (14%), Positives = 127/395 (32%), Gaps = 69/395 (17%) Query: 77 IIDCGFEHPSEVQQHTIPQSIHGTDVLC-QAKSGLGKTAVFVLSTLQQLDPVPGEVAVVV 135 I+ + P Q+ H +L ++G GKT + D +P + ++ Sbjct: 31 ILKARRKLPVNKQRQEFLDLYHNNQILVFVGETGSGKTT--QIPQYVLYDELPHQTGKLI 88 Query: 136 IC--NARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPG 193 C R A + + + LLK Sbjct: 89 ACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDG--------- 139 Query: 194 RLKALVREKYIDLSHVKN--FVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLS 251 L+RE D + ++DE + D+ + + +D ++++ SATL Sbjct: 140 ---QLLREAMHDRDMSRYSCIILDEAHERTLATDILMALLKQLSERRKDLKIIVMSATL- 195 Query: 252 QEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEERE----KNRKLAQLLDDLEFN 307 + + F PL H ++ +Y ER+ R + Q+ Sbjct: 196 -DAQKFQSYFFNAPLLAVPGR-----THPVEIFYTPEAERDYVEAAIRTVLQIHACEPEG 249 Query: 308 QVIIFV-----------KSTTRANELTKLLNASNFPAITVHGHMK--QEER--IARYKAF 352 +++F+ + + +E+ + +A ++G + Q++R + F Sbjct: 250 DILLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPF 309 Query: 353 KDF---EKRICVSTDVFGRGIDIERINLAI--------NYDL----------TNEADQYL 391 + ++ V+T++ + I+ I + Y+ Sbjct: 310 RPGGRPGRKCIVATNIAETSLTIDGIVYVVDPGFSKQKIYNPRTRVESLLVSPISKASAQ 369 Query: 392 HRVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERF 426 R GRAGR G + + ++ L I++ + Sbjct: 370 QRAGRAGRT-RPGKCFRLYTEEAFKKEL--IEQTY 401 >4A2W-A nrPDB Length = 936 Score = 58.8 bits (141), Expect = 4e-09, Method: Composition-based stats. Identities = 36/175 (20%), Positives = 64/175 (36%), Gaps = 24/175 (13%) Query: 289 EEREKNRKLAQLLDD----LEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEE 344 E K +L +LDD + ++F K+ + L K + + G + Sbjct: 610 NENPKLEELVCILDDAYRYNPQTRTLLFAKTRALVSALKKCMEENPILNYIKPGVLMGRG 669 Query: 345 RIA------------RYKAFKDFE-KRICVSTDVFGRGIDIERINLAINYDLTNEADQYL 391 R AFK + R+ ++T V GIDI + NL + Y+ + + + Sbjct: 670 RRDQTTGMTLPSQKGVLDAFKTSKDNRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMI 729 Query: 392 HRVGRAGRFGTKGLAISFVSSK---EDEEVLAKIQERFDVKIAEFPEEGIDPSTY 443 GR GR I S E+E+ +E + + + + D T+ Sbjct: 730 QVRGR-GRAA-GSKCILVTSKTEVVENEKCNRYKEEMMNKAVEKI--QKWDEETF 780 Score = 53.8 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 61/339 (17%), Positives = 108/339 (31%), Gaps = 54/339 (15%) Query: 66 DFLLKPELSRAIIDCGFEHPSEV---------QQHTIPQSIHGTDVLCQAKSGLGKTAVF 116 D L L G P V Q +I+G + L A +G GKT V Sbjct: 223 DDNLSENL--GSAAEGIGKPPPVYETKKARSYQIELAQPAINGKNALICAPTGSGKTFVS 280 Query: 117 VLSTLQQLDPVPGEVAV-VVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDA 175 +L +P VV + Y+ + + G + Sbjct: 281 ILICEHHFQNMPAGRKAKVVFLATKVPVYEQQKNVFKHHFERQGYSVQGISGENFSNVSV 340 Query: 176 ELLKNKDTAPHIVVATPGRLKALVREKYI-DLSHVKNFVIDECDKVLEELD----MRRDV 230 E I+V TP L + + LS + DEC M R + Sbjct: 341 E---KVIEDSDIIVVTPQILVNSFEDGTLTSLSIFTLMIFDECHNTTGNHPYNVLMTRYL 397 Query: 231 QEIFRATPRDKQVMMFSAT--------LSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQ 282 ++ F + + Q++ +A+ + + I IC L + L+I + + LQ Sbjct: 398 EQKFNSASQLPQILGLTASVGVGNAKNIEETIEHICS--LCSYLDIQAISTVRENIQELQ 455 Query: 283 QYYIKLEEREKNRKLAQLLDDLEFNQ--VII---------FVKSTTRANELTKLLNASNF 331 ++ K +L+ N II +++ + L++ + +F Sbjct: 456 RFM------NKPEIDVRLVKRRIHNPFAAIISNLMSETEALMRTIAYVDTLSQN-SKKDF 508 Query: 332 PAITVHGHMKQEERIARYKAF--KDFEKRIC----VSTD 364 + +R R K+ E RIC + T+ Sbjct: 509 GTQNYEHWIVVTQRKCRLLQLEDKEEESRICRALFICTE 547 >4A2Q-A nrPDB Length = 797 Score = 58.8 bits (141), Expect = 5e-09, Method: Composition-based stats. Identities = 36/175 (20%), Positives = 64/175 (36%), Gaps = 24/175 (13%) Query: 289 EEREKNRKLAQLLDD----LEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEE 344 E K +L +LDD + ++F K+ + L K + + G + Sbjct: 610 NENPKLEELVCILDDAYRYNPQTRTLLFAKTRALVSALKKCMEENPILNYIKPGVLMGRG 669 Query: 345 RIA------------RYKAFKDFE-KRICVSTDVFGRGIDIERINLAINYDLTNEADQYL 391 R AFK + R+ ++T V GIDI + NL + Y+ + + + Sbjct: 670 RRDQTTGMTLPSQKGVLDAFKTSKDNRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMI 729 Query: 392 HRVGRAGRFGTKGLAISFVSSK---EDEEVLAKIQERFDVKIAEFPEEGIDPSTY 443 GR GR I S E+E+ +E + + + + D T+ Sbjct: 730 QVRGR-GRAA-GSKCILVTSKTEVVENEKCNRYKEEMMNKAVEKI--QKWDEETF 780 Score = 53.4 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 61/339 (17%), Positives = 108/339 (31%), Gaps = 54/339 (15%) Query: 66 DFLLKPELSRAIIDCGFEHPSEV---------QQHTIPQSIHGTDVLCQAKSGLGKTAVF 116 D L L G P V Q +I+G + L A +G GKT V Sbjct: 223 DDNLSENL--GSAAEGIGKPPPVYETKKARSYQIELAQPAINGKNALICAPTGSGKTFVS 280 Query: 117 VLSTLQQLDPVPGEVAV-VVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDA 175 +L +P VV + Y+ + + G + Sbjct: 281 ILICEHHFQNMPAGRKAKVVFLATKVPVYEQQKNVFKHHFERQGYSVQGISGENFSNVSV 340 Query: 176 ELLKNKDTAPHIVVATPGRLKALVREKYI-DLSHVKNFVIDECDKVLEELD----MRRDV 230 E I+V TP L + + LS + DEC M R + Sbjct: 341 E---KVIEDSDIIVVTPQILVNSFEDGTLTSLSIFTLMIFDECHNTTGNHPYNVLMTRYL 397 Query: 231 QEIFRATPRDKQVMMFSAT--------LSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQ 282 ++ F + + Q++ +A+ + + I IC L + L+I + + LQ Sbjct: 398 EQKFNSASQLPQILGLTASVGVGNAKNIEETIEHICS--LCSYLDIQAISTVRENIQELQ 455 Query: 283 QYYIKLEEREKNRKLAQLLDDLEFNQ--VII---------FVKSTTRANELTKLLNASNF 331 ++ K +L+ N II +++ + L++ + +F Sbjct: 456 RFM------NKPEIDVRLVKRRIHNPFAAIISNLMSETEALMRTIYSVDTLSQN-SKKDF 508 Query: 332 PAITVHGHMKQEERIARYKAF--KDFEKRIC----VSTD 364 + +R R K+ E RIC + T+ Sbjct: 509 GTQNYEHWIVVTQRKCRLLQLEDKEEESRICRALFICTE 547 >3DIN-A nrPDB Length = 871 Score = 58.8 bits (141), Expect = 5e-09, Method: Composition-based stats. Identities = 32/160 (20%), Positives = 66/160 (41%), Gaps = 12/160 (7%) Query: 266 LEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDD--LEFNQVIIFVKSTTRANELT 323 +E+ V K + + ++EK K+ + ++ + V++ S ++ L+ Sbjct: 432 MEVVVIPTHKPMIRKDHDDLVFRTQKEKYEKIVEEIEKRYKKGQPVLVGTTSIEKSELLS 491 Query: 324 KLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDI---ERINLAIN 380 +L P ++ ++E KA + + ++T++ GRG DI + Sbjct: 492 SMLKKKGIPHQVLNAKYHEKEAEIVAKAGQKGM--VTIATNMAGRGTDIKLGPGVAELGG 549 Query: 381 YDLTNEADQYLHRV-----GRAGRFGTKGLAISFVSSKED 415 + R+ GRAGR G G +I F+S ++D Sbjct: 550 LCIIGTERHESRRIDNQLRGRAGRQGDPGESIFFLSLEDD 589 Score = 31.1 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 5/57 (8%) Query: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLST 120 F+ F L E +R + P +VQ G + + K+G GKT + Sbjct: 58 FEAFALVREAARRTLGM---RPFDVQVMGGIALHEGK--VAEMKTGEGKTLAATMPI 109 >5XDR-A nrPDB Length = 690 Score = 58.4 bits (140), Expect = 5e-09, Method: Composition-based stats. Identities = 57/373 (15%), Positives = 112/373 (30%), Gaps = 76/373 (20%) Query: 101 DVLCQAK-------SGLGKTAVFVLS--TLQQLDPVPGEV-AVVVICNARELAYQIRNEY 150 D+L + + +G GKT + ++ + +PG V R A + Sbjct: 43 DILVRHQSFVLVGETGSGKTT--QIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRV 100 Query: 151 LRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVK 210 M + S +LK T G L + L Sbjct: 101 ADEMDVMLGQEVGYSIRFEDCSSAKTILK---------YMTDGMLLREAMNDPL-LERYG 150 Query: 211 NFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFL-------- 262 ++DE + D+ V + D +V++ SATL +F Sbjct: 151 VIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLD------AGKFQIYFDNCPL 204 Query: 263 ------QNPLEIFVDDEAK---LTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFV 313 +P+EIF E + L I + E E+ L L E ++ Sbjct: 205 LTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEA---C 261 Query: 314 -KSTTRANELTKLLNASNFPAITVHGHMKQEERIARYK----AFKDFEK--RICVSTDVF 366 + ++L + + I ++ + +++ ++ ++ ++ VST++ Sbjct: 262 KRIKREVDDLGPEV--GDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIA 319 Query: 367 GRGIDIERINLAINYDLTN------------------EADQYLHRVGRAGRFGTKGLAIS 408 + I+ + I+ R GRAGR G Sbjct: 320 ETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRT-RPGKCFR 378 Query: 409 FVSSKEDEEVLAK 421 + K + + Sbjct: 379 LYTEKAYKTEMQD 391 >5FMF-1 nrPDB Length = 492 Score = 58.4 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 60/360 (16%), Positives = 116/360 (32%), Gaps = 60/360 (16%) Query: 84 HPS----EVQQHTIPQSIHG---TDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVI 136 PS Q+ ++ + + G GKT V ++ + V+V+ Sbjct: 64 KPSTQIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLV-GITAACTIKKS-----VIVL 117 Query: 137 CNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVA-TPGRL 195 C + Q R ++L++ P+ AVF + + + + + +VA T R Sbjct: 118 CTSSVSVMQWRQQFLQWCTLQPE-NCAVFT--SDNKEMFQTESGLVVSTYSMVANTRNRS 174 Query: 196 KALVR-EKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEI 254 + ++ ++DE V + RR V I + +ATL +E Sbjct: 175 HDSQKVMDFLTGREWGFIILDEVHVVPAAM-FRRVVSTIAAHAK-----LGLTATLVRED 228 Query: 255 RPICR-RFLQNPLE----------------IFVDDEAKLTLHGLQQYYIKLEERE----- 292 I FL P + + Q Y++ R+ Sbjct: 229 DKIGDLNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLY 288 Query: 293 -----KNRKLAQL--LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEER 345 K + L + +++I+F + L + P ++G Q+ER Sbjct: 289 IMNPTKFQACQFLIQYHERRGDKIIVF---SDNVYALQEYALKMGKP--FIYGSTPQQER 343 Query: 346 IARYKAFK-DFEKRICVSTDVFGRGIDIERINLAINYDL-TNEADQYLHRVGRAGRFGTK 403 + + F+ + + + V ID+ I Q R+GR R + Sbjct: 344 MNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRR 403 >4A36-A nrPDB Length = 556 Score = 58.1 bits (139), Expect = 7e-09, Method: Composition-based stats. Identities = 36/175 (20%), Positives = 64/175 (36%), Gaps = 24/175 (13%) Query: 289 EEREKNRKLAQLLDD----LEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEE 344 E K +L +LDD + ++F K+ + L K + + G + Sbjct: 369 NENPKLEELVCILDDAYRYNPQTRTLLFAKTRALVSALKKCMEENPILNYIKPGVLMGRG 428 Query: 345 RIA------------RYKAFKDFE-KRICVSTDVFGRGIDIERINLAINYDLTNEADQYL 391 R AFK + R+ ++T V GIDI + NL + Y+ + + + Sbjct: 429 RRDQTTGMTLPSQKGVLDAFKTSKDNRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMI 488 Query: 392 HRVGRAGRFGTKGLAISFVSSK---EDEEVLAKIQERFDVKIAEFPEEGIDPSTY 443 GR GR I S E+E+ +E + + + + D T+ Sbjct: 489 QVRGR-GRAA-GSKCILVTSKTEVVENEKCNRYKEEMMNKAVEKI--QKWDEETF 539 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 27/133 (20%), Positives = 42/133 (31%), Gaps = 5/133 (3%) Query: 89 QQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAV-VVICNARELAYQIR 147 Q +I+G + L A +G GKT V +L +P VV + Y+ + Sbjct: 12 QIELAQPAINGKNALICAPTGSGKTFVSILICEHHFQNMPAGRKAKVVFLATKVPVYEQQ 71 Query: 148 NEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYI-DL 206 + G + E I+V TP L + + L Sbjct: 72 KNVFKHHFERQGYSVQGISGENFSNVSVE---KVIEDSDIIVVTPQILVNSFEDGTLTSL 128 Query: 207 SHVKNFVIDECDK 219 S + DEC Sbjct: 129 SIFTLMIFDECHN 141 >5SVA-Z nrPDB Length = 843 Score = 58.1 bits (139), Expect = 9e-09, Method: Composition-based stats. Identities = 60/360 (16%), Positives = 116/360 (32%), Gaps = 60/360 (16%) Query: 84 HPS----EVQQHTIPQSIHG---TDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVI 136 PS Q+ ++ + + G GKT V ++ + V+V+ Sbjct: 357 KPSTQIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLV-GITAACTIKKS-----VIVL 410 Query: 137 CNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVA-TPGRL 195 C + Q R ++L++ P+ AVF + + + + + +VA T R Sbjct: 411 CTSSVSVMQWRQQFLQWCTLQPE-NCAVFT--SDNKEMFQTESGLVVSTYSMVANTRNRS 467 Query: 196 KALVR-EKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEI 254 + ++ ++DE V + RR V I + +ATL +E Sbjct: 468 HDSQKVMDFLTGREWGFIILDEVHVVPAAM-FRRVVSTIAAHAK-----LGLTATLVRED 521 Query: 255 RPICR-RFLQNPLE----------------IFVDDEAKLTLHGLQQYYIKLEERE----- 292 I FL P + + Q Y++ R+ Sbjct: 522 DKIGDLNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLY 581 Query: 293 -----KNRKLAQL--LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEER 345 K + L + +++I+F + L + P ++G Q+ER Sbjct: 582 IMNPTKFQACQFLIQYHERRGDKIIVF---SDNVYALQEYALKMGKP--FIYGSTPQQER 636 Query: 346 IARYKAFK-DFEKRICVSTDVFGRGIDIERINLAINYDL-TNEADQYLHRVGRAGRFGTK 403 + + F+ + + + V ID+ I Q R+GR R + Sbjct: 637 MNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRR 696 >6F4A-B nrPDB Length = 644 Score = 57.3 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 59/357 (16%), Positives = 130/357 (36%), Gaps = 61/357 (17%) Query: 102 VLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVK 161 ++ + GKT +LQ+L R LA R Y +F +V+ Sbjct: 162 IMHVGPTNSGKTFR----SLQKLKAADRGYYA---GPLRLLA---REVYEKF--KHENVR 209 Query: 162 TAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVL 221 + G E++K+ D + T G ++ + + D V+DE +++ Sbjct: 210 CNLLTG-------EEVIKDLDEMGNEANLTSGTIEMIPLNQNFD-----VVVLDEI-QMM 256 Query: 222 EELDMR-RDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHG 280 +LD + A ++ ++T+ + ++ I KLT++ Sbjct: 257 ADLDRGWAWTNALLGAKAKEVHCCGEASTIP-----LIKK-------IVEMTGDKLTINE 304 Query: 281 LQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHM 340 ++ + E E L + L+ ++ + ++ + A ++G + Sbjct: 305 YERMGKLVVEEE---ALTKGYHSLKKGDCVVAFSKKAILDLKLEIEKKTELKAAVIYGSL 361 Query: 341 KQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINY-------DLTNEADQYLHR 393 E R+ + F E I +++D G G+++ + D+ + + + Sbjct: 362 PPETRVKQANLFNSGEFDILIASDAIGMGLNLSIDRVVFTTSKKFDGRDMVDMTSSAIKQ 421 Query: 394 V-GRAGRF-----GTKGLAISFVSSKEDEEVLAKIQERFDVKIAEF------PEEGI 438 + GRAGRF L + ++++ + VL ++E + I P + I Sbjct: 422 IGGRAGRFKQNIHDNGELPVGYITAVK-PNVLKAVREAINAPIEYLTSATTWPTDEI 477 >6DCR-A nrPDB Length = 694 Score = 55.7 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 59/388 (15%), Positives = 113/388 (29%), Gaps = 104/388 (26%) Query: 108 SGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQ-IRNEYLRFSKYMPDVKTAVFY 166 +G GKT V+ LS L+ + +V+ L Q I RF+ + + + + Sbjct: 188 TGSGKTEVY-LSVLENVLAQGK--QALVMVPEIGLTPQTIARFRERFNAPVEVLHSGL-- 242 Query: 167 GGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVL--EEL 224 + + LK K+ IV+ T L ++ VIDE ++ Sbjct: 243 --NDSERLSAWLKAKNGEAAIVIGTRSALFTP-------FKNLGVIVIDEEHDSSYKQQE 293 Query: 225 DMRRDVQEIFRATPRDKQ--VMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQ 282 R +++ +Q +++ SAT + +C + + + A Sbjct: 294 GWRYHARDLAVYRAHSEQIPIILGSAT--PALETLCNVQQKKYRLLRLTRRAG-NARPAI 350 Query: 283 QYYIKLEEREKNRKLAQLL------DDLEFNQVIIFVKST--------TRANELTKL--- 325 Q+ + L+ ++ LA L NQVI+F+ + + Sbjct: 351 QHVLDLKGQKVQAGLAPALITRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRC 410 Query: 326 -----LNASNFPAITVHGH---------------------------------------MK 341 L+ + H + Sbjct: 411 DHYYTLHQAQHHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTLAPLFPGVPIS 470 Query: 342 QEERIARYKA---------FKDFEKRICVSTDVFGRGIDIERINLAINYD-----LTNEA 387 + +R + RI + T + +G + L D + + Sbjct: 471 RIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSADF 530 Query: 388 DQ-------YLHRVGRAGRFGTKGLAIS 408 Y GRAGR G +G + Sbjct: 531 RSAERFAQLYTQVAGRAGRAGKQGEVVL 558 Score = 31.5 bits (70), Expect = 0.87, Method: Composition-based stats. Identities = 13/82 (15%), Positives = 31/82 (37%), Gaps = 3/82 (3%) Query: 288 LEEREKNRKLAQLLDDL--EFNQVIIFVKSTTRANE-LTKLLNASNFPAITVHGHMKQEE 344 + K +L+++ + Q ++ V + + + N P +H + E Sbjct: 187 VTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVLHSGLNDSE 246 Query: 345 RIARYKAFKDFEKRICVSTDVF 366 R++ + K+ E I + T Sbjct: 247 RLSAWLKAKNGEAAIVIGTRSA 268 >6I3O-A nrPDB Length = 677 Score = 55.7 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 44/359 (12%), Positives = 103/359 (28%), Gaps = 49/359 (13%) Query: 91 HTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEY 150 I ++ ++G GKT + G + R A + Sbjct: 20 QIIQAVKDNQILIVVGETGSGKTTQVTQYLAEAGFTKYGMIG--CTQPRRVAAVSVAKRV 77 Query: 151 LRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYI---DLS 207 + ++ A +K +++ + + DL Sbjct: 78 AEEVGCQLGQEVGYTIRFEDVTSPATKIKYMTDG-------------MLQREILMDPDLK 124 Query: 208 HVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLE 267 ++DE + D+ + + D +V++ SATL + F P+ Sbjct: 125 RYSVIMLDEAHERTIATDVLFALLKKTVKRRPDLKVIVTSATL--DAEKFSEYFNSCPIF 182 Query: 268 IFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTR----ANELT 323 + + ++ E + Q+ +++F+ L Sbjct: 183 TIPGRTFPVEILYSREPEPDYLEA-ALTTVMQIHLTEPPGDILVFLTGQEEIDTACEILY 241 Query: 324 KLLNASNFPA-----ITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLA 378 + + A + ++ + E + ++ +++ ++T++ I I+ I Sbjct: 242 ERMKALGPSVPELIILPIYSALPSEMQSRIFEPAPPGSRKVVIATNIAETSITIDYIYYV 301 Query: 379 IN--------YDL----------TNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVL 419 ++ YD Q R GRAGR G G + + + Sbjct: 302 VDPGFVKQNAYDPKLGMDSLVVTPISQAQANQRAGRAGRTG-PGKCFRLYTEAAYQSEM 359 >6FTX-W nrPDB Length = 878 Score = 55.0 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 56/157 (35%), Gaps = 5/157 (3%) Query: 290 EREKNRKLAQLLDDLEFN--QVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIA 347 K L QLL L+ + +V+IF + + L L+ + G + +R Sbjct: 498 SSGKMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRI 557 Query: 348 RYKAFKD---FEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKG 404 F + +ST G GI++ + + +D L + RA R G K Sbjct: 558 SIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKN 617 Query: 405 LAISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPS 441 + + +D ++ I E+ + I S Sbjct: 618 HVMVYRLVSKDTVEEEVLERARKKMILEYDMDSIGES 654 >5WSO-A nrPDB Length = 476 Score = 55.0 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 46/278 (16%), Positives = 99/278 (35%), Gaps = 36/278 (12%) Query: 108 SGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYG 167 +G GKT + ++++ V+V+ R A + P + + G Sbjct: 21 TGAGKTTELPKAVIEEIGRHK---RVLVLIPLRAAAESVYQYMR---LKHPSISFNLRIG 74 Query: 168 GTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKN--FVIDECDKVLEELD 225 K D A I A+ G + + + + V+ +DE + Sbjct: 75 DM---------KEGDMATGITYASYGYFCQM-PQPKLRAAMVEYSYIFLDEYHC--ATPE 122 Query: 226 MRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYY 285 + +I R + +V+ +AT + + ++ P+E F+ E Q+ Sbjct: 123 QLAIIGKIHRFS-ESIRVVAMTATPAGSVTTTGQKH---PIEEFIAPEVMKGEDLGSQFL 178 Query: 286 IKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEER 345 L +D+++ N +++FV + A E+ K L A + + + E Sbjct: 179 DIAG-------LKIPVDEMKGN-MLVFVPTRNMAVEVAKKLKAKGYNSGYYYSG----ED 226 Query: 346 IARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDL 383 A + + V+T+ G+ + ++ I+ L Sbjct: 227 PANLRVVTSQSPYVIVATNAIESGVTLPDLDTVIDTGL 264 >4CBI-A nrPDB Length = 516 Score = 55.0 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 50/321 (15%), Positives = 109/321 (33%), Gaps = 59/321 (18%) Query: 108 SGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYG 167 +G GKT S ++++ V+V+ R A + + P + + G Sbjct: 53 TGAGKTTELPRSVIEEIGRHK---RVLVLIPLRAAAESVYQYMRQKH---PSIAFNLRIG 106 Query: 168 GTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKN--FVIDECDKVLEELD 225 +K D A I A+ G + + + + V+ +DE + Sbjct: 107 ---------EMKEGDMATGITYASYGYFCQM-SQPKLRAAMVEYSFIFLDEYHC--ATPE 154 Query: 226 MRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYY 285 + +I R + + +V+ +AT + + ++ P+E F+ E +Y Sbjct: 155 QLAIMGKIHRFS-ENLRVVAMTATPAGTVTTTGQKH---PIEEFIAPEVMKGEDLGSEYL 210 Query: 286 IKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEER 345 L +++++ N +++FV + A E K L A + + + E Sbjct: 211 DIAG-------LKIPVEEMKNN-MLVFVPTRNMAVEAAKKLKAKGYNSGYYYSG----ED 258 Query: 346 IARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDL---------TN----------- 385 + + + V+T+ G+ + +++ ++ L Sbjct: 259 PSNLRVVTSQSPYVVVATNAIESGVTLPDLDVVVDTGLKCEKRIRLSPKMPFIVTGLKRM 318 Query: 386 --EADQYLHRVGRAGRFGTKG 404 + R GR GR G Sbjct: 319 AVTIGEQAQRRGRVGRV-KPG 338 >4NL8-A nrPDB Length = 747 Score = 54.6 bits (130), Expect = 9e-08, Method: Composition-based stats. Identities = 61/388 (15%), Positives = 113/388 (29%), Gaps = 104/388 (26%) Query: 108 SGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQ-IRNEYLRFSKYMPDVKTAVFY 166 +G GKT V+ LS L+ + +V+ L Q I RF+ + + + + Sbjct: 241 TGSGKTEVY-LSVLENVLAQ--GRQALVMVPEIGLTPQTIARFRQRFNAPVEVLHSGL-- 295 Query: 167 GGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVL--EEL 224 + + LK K+ IV+ T L + VIDE ++ Sbjct: 296 --NDSERLSAWLKAKNGEAAIVIGTRSSLFTP-------FKDLGVIVIDEEHDSSYKQQE 346 Query: 225 DMRRDVQEIFRATPRDKQV--MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQ 282 R +++ +Q+ ++ SAT + E R+ ++ + A Q Sbjct: 347 GWRYHARDLAVWRAHSEQIPIILGSATPALETLHNVRQ--GKYRQLTLSKRAG-NARPAQ 403 Query: 283 QYYIKLEEREKNRKLAQLL------DDLEFNQVIIFVKST--------TRANELTKL--- 325 Q+ + L+ + L+ L NQVI+F+ + + Sbjct: 404 QHVLDLKGQPLQAGLSPALISRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRC 463 Query: 326 -----LNASNFPAITVHGH---------------------------------------MK 341 L+ + H + Sbjct: 464 DSYYTLHQAQHHLRCHHCDSQRPIPRQCPSCGSTHLVPVGIGTEQLEQALAPLFPEVPIS 523 Query: 342 QEERIARYKA---------FKDFEKRICVSTDVFGRGIDIERINLAINYD-----LTNEA 387 + +R + RI + T + +G + L D + + Sbjct: 524 RIDRDTTSRKGALEEHLAAVHRGGARILIGTQMLAKGHHFPDVTLVSLLDVDGALFSADF 583 Query: 388 DQ-------YLHRVGRAGRFGTKGLAIS 408 Y GRAGR G +G I Sbjct: 584 RSAERFAQLYTQVSGRAGRAGKQGEVIL 611 >5WX1-A nrPDB Length = 733 Score = 54.6 bits (130), Expect = 9e-08, Method: Composition-based stats. Identities = 49/321 (15%), Positives = 109/321 (33%), Gaps = 59/321 (18%) Query: 108 SGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYG 167 +G GKT S ++++ V+V+ R A + + P + + G Sbjct: 278 TGAGKTTELPRSVIEEIGRHK---RVLVLIPLRAAAESVYQYMRQKH---PSIAFNLRIG 331 Query: 168 GTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKN--FVIDECDKVLEELD 225 +K D A I A+ G + + + + V+ +DE + Sbjct: 332 ---------EMKEGDMATGITYASYGYFCQM-PQPKLRAAMVEYSFIFLDEYHC--ATPE 379 Query: 226 MRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYY 285 + +I R + + +V+ +AT + + ++ P+E F+ E +Y Sbjct: 380 QLAIMGKIHRFS-ENLRVVAMTATPAGTVTTTGQKH---PIEEFIAPEVMKGEDLGSEYL 435 Query: 286 IKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEER 345 L +++++ N +++FV + A E K L A + + + E Sbjct: 436 DIAG-------LKIPVEEMKSN-MLVFVPTRNMAVETAKKLKAKGYNSGYYYSG----ED 483 Query: 346 IARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYD----------------------L 383 + + + V+T+ G+ + +++ ++ + Sbjct: 484 PSNLRVVTSQSPYVVVATNAIESGVTLPDLDVVVDTGLKCEKRIRLSSKMPFIVTGLKRM 543 Query: 384 TNEADQYLHRVGRAGRFGTKG 404 + R GR GR G Sbjct: 544 AVTIGEQAQRRGRVGRV-KPG 563 >3RC8-A nrPDB Length = 677 Score = 54.2 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 23/149 (15%) Query: 301 LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKD--FEKR 358 LD+L I+ S +++ + + ++G + ++A+ K F D + Sbjct: 316 LDNLRPGDCIV-CFSKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQAKKFNDPNDPCK 374 Query: 359 ICVSTDVFGRGIDIERINLAINYDL--------------TNEADQYLHRVGRAGRFG--- 401 I V+TD G G+++ I I Y L Q L GRAGRF Sbjct: 375 ILVATDAIGMGLNLS-IRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRF 433 Query: 402 TKGLAISFVSSKEDEEVLAKIQERFDVKI 430 +G + + ED +L +I +R I Sbjct: 434 KEGEVTTM--NHEDLSLLKEILKRPVDPI 460 >6NMI-A nrPDB Length = 653 Score = 54.2 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 38/225 (16%), Positives = 72/225 (32%), Gaps = 43/225 (19%) Query: 211 NFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICR-RFLQNP---- 265 ++DE + ++ RR + + + +ATL +E I FL P Sbjct: 360 LMILDEVHTIPAKM-FRRVLTIVQAHCK-----LGLTATLVREDDKIVDLNFLIGPKLYE 413 Query: 266 ------------LEIFVDDEAKLTLHGLQQYYIKLEERE----------KNRKLAQL--L 301 ++ + + Y+ ++ ++ K R L Sbjct: 414 ANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKF 473 Query: 302 DDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDF-EKRIC 360 + +++I+F + E LN ++G Q ER+ + FK + Sbjct: 474 HERRNDKIIVFADNVFALKEYAIRLNKP-----YIYGPTSQGERMQILQNFKHNPKINTI 528 Query: 361 VSTDVFGRGIDIERINLAINYDLT-NEADQYLHRVGRAGRFGTKG 404 + V D+ N+ I Q R+GR R KG Sbjct: 529 FISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRA-KKG 572 >5OF4-A nrPDB Length = 553 Score = 54.2 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 38/225 (16%), Positives = 72/225 (32%), Gaps = 43/225 (19%) Query: 211 NFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICR-RFLQNP---- 265 ++DE + ++ RR + + + +ATL +E I FL P Sbjct: 208 LMILDEVHTIPAKM-FRRVLTIVQAHCK-----LGLTATLVREDDKIVDLNFLIGPKLYE 261 Query: 266 ------------LEIFVDDEAKLTLHGLQQYYIKLEERE----------KNRKLAQL--L 301 ++ + + Y+ ++ ++ K R L Sbjct: 262 ANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKF 321 Query: 302 DDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDF-EKRIC 360 + +++I+F + E LN ++G Q ER+ + FK + Sbjct: 322 HERRNDKIIVFADNVFALKEYAIRLNKP-----YIYGPTSQGERMQILQNFKHNPKINTI 376 Query: 361 VSTDVFGRGIDIERINLAINYDLT-NEADQYLHRVGRAGRFGTKG 404 + V D+ N+ I Q R+GR R KG Sbjct: 377 FISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRA-KKG 420 >5IY9-V nrPDB Length = 782 Score = 54.2 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 38/225 (16%), Positives = 72/225 (32%), Gaps = 43/225 (19%) Query: 211 NFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICR-RFLQNP---- 265 ++DE + ++ RR + + + +ATL +E I FL P Sbjct: 437 LMILDEVHTIPAKM-FRRVLTIVQAHCK-----LGLTATLVREDDKIVDLNFLIGPKLYE 490 Query: 266 ------------LEIFVDDEAKLTLHGLQQYYIKLEERE----------KNRKLAQL--L 301 ++ + + Y+ ++ ++ K R L Sbjct: 491 ANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKF 550 Query: 302 DDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDF-EKRIC 360 + +++I+F + E LN ++G Q ER+ + FK + Sbjct: 551 HERRNDKIIVFADNVFALKEYAIRLNKP-----YIYGPTSQGERMQILQNFKHNPKINTI 605 Query: 361 VSTDVFGRGIDIERINLAINYDLT-NEADQYLHRVGRAGRFGTKG 404 + V D+ N+ I Q R+GR R KG Sbjct: 606 FISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRA-KKG 649 >5OQJ-7 nrPDB Length = 843 Score = 53.8 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 38/224 (16%), Positives = 69/224 (30%), Gaps = 42/224 (18%) Query: 211 NFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICR-RFLQNPLE-- 267 ++DE V + RR V I + +ATL +E I FL P Sbjct: 484 FIILDEVHVVPAAM-FRRVVSTIAAHAK-----LGLTATLVREDDKIGDLNFLIGPKLYE 537 Query: 268 --------------IFVDDEAKLTLHGLQQYYIKLEERE----------KNRKLAQL--L 301 + + Q Y++ R+ K + L Sbjct: 538 ANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQY 597 Query: 302 DDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFK-DFEKRIC 360 + +++I+F + L + P ++G Q+ER+ + F+ + + Sbjct: 598 HERRGDKIIVF---SDNVYALQEYALKMGKP--FIYGSTPQQERMNILQNFQYNDQINTI 652 Query: 361 VSTDVFGRGIDIERINLAINYDL-TNEADQYLHRVGRAGRFGTK 403 + V ID+ I Q R+GR R + Sbjct: 653 FLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRR 696 >4A4Z-A nrPDB Length = 997 Score = 53.8 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 61/167 (36%), Gaps = 21/167 (12%) Query: 89 QQHTIPQSIHGTDVLCQAKSGLGKT--AVFVLSTLQQLDPVPGEVAVVVICNARELAYQI 146 Q+ + G V A + GKT A + ++ + + + L+ Q Sbjct: 44 QKEAVYHLEQGDSVFVAAHTSAGKTVVAEYAIAMAHR-----NMTKTIYTSPIKALSNQ- 97 Query: 147 RNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDL 206 ++ F + DV + G I+ DA ++ T L++++ + Sbjct: 98 --KFRDFKETFDDVNIGLITGDVQINPDANC----------LIMTTEILRSMLYRGADLI 145 Query: 207 SHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQE 253 V+ + DE V + D +E+ P+ + ++ SAT+ Sbjct: 146 RDVEFVIFDEVHYV-NDQDRGVVWEEVIIMLPQHVKFILLSATVPNT 191 Score = 49.2 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 27/192 (14%), Positives = 61/192 (31%), Gaps = 29/192 (15%) Query: 249 TLSQEIRPICRR-FLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRK-------LAQL 300 T + + + +R L + +F + L+ +EK++ + +L Sbjct: 323 TWPEIVNYLRKRELLPMVVFVFSKKRCEEYADWLEGINF-CNNKEKSQIHMFIEKSITRL 381 Query: 301 LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRIC 360 + I+ +S L HG + + F ++ Sbjct: 382 KKEDRDLPQILKTRS----------LLERGIAV--HHGGLLPIVKELIEILFSKGFIKVL 429 Query: 361 VSTDVFGRGIDIERINLAIN----YDLTNEAD----QYLHRVGRAGRFGTKGLAISFVSS 412 +T+ F G+++ + + +D + ++ GRAGR G V + Sbjct: 430 FATETFAMGLNLPTRTVIFSSIRKHDGNGLRELTPGEFTQMAGRAGRRGLDSTGTVIVMA 489 Query: 413 KEDEEVLAKIQE 424 +A +E Sbjct: 490 YNSPLSIATFKE 501 >5WDX-A nrPDB Length = 649 Score = 53.4 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 38/266 (14%), Positives = 82/266 (30%), Gaps = 54/266 (20%) Query: 106 AKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVF 165 A +G GK+ T + V+V+ + + P+++T V Sbjct: 222 APTGSGKS------TKVPVAYAAQGYKVLVLNPSVAATLGFGAYLSKAHGINPNIRTGV- 274 Query: 166 YGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKV--LEE 223 + T I +T G+ + + + DEC V Sbjct: 275 -------------RTVMTGEAITYSTYGK---FLADGGCASGAYDIIICDECHAVDATSI 318 Query: 224 LDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQ 283 L + + + T + ++ +AT + + E+ + E ++ +G Sbjct: 319 LGIGTVLDQ--AETAGVRLTVLATATPPGSVTTPH----PDIEEVGLGREGEIPFYGRAI 372 Query: 284 YYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQE 343 L ++ + +IF S + +EL L A+ + + Sbjct: 373 P----------------LSCIKGGRHLIFCHSKKKCDELAAALRGMGLNAVAYYRGLD-- 414 Query: 344 ERIARYKAFKDFEKRICVSTDVFGRG 369 ++ A + + V+TD G Sbjct: 415 --VSIIPA--QGDV-VVVATDALMTG 435 >4UAQ-A nrPDB Length = 778 Score = 53.1 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 33/165 (20%), Positives = 62/165 (37%), Gaps = 19/165 (11%) Query: 268 IFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDD--LEFNQVIIFVKSTTRANELTKL 325 + K + + + + KN + + + + V++ + + EL + Sbjct: 402 VSPIPPNKPNIREDEADRVYITTAAKNDGIVEHITEVHQRGQPVLVGTRDVAESEELHER 461 Query: 326 LNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDI----------ERI 375 L PA+ ++ EE +A K + VST + GRG DI +R+ Sbjct: 462 LVRRGVPAVVLNAKNDAEEARVIAEAGKYGA--VTVSTQMAGRGTDIRLGGSDEADHDRV 519 Query: 376 NLAINYDLTNEADQYLHRV-----GRAGRFGTKGLAISFVSSKED 415 + + R+ GRAGR G G ++ F S ++D Sbjct: 520 AELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDD 564 >4B6E-A nrPDB Length = 683 Score = 52.7 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 35/270 (12%), Positives = 79/270 (29%), Gaps = 62/270 (22%) Query: 106 AKSGLGKT----AVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVK 161 A +G GK+ A + V+V+ + + P+++ Sbjct: 239 APTGSGKSTKVPAAYA----------AQGYKVLVLNPSVAATLGFGAYMSKAHGIDPNIR 288 Query: 162 TAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVL 221 T V + T + +T G+ + + + DEC Sbjct: 289 TGV--------------RTITTGAPVTYSTYGK---FLADGGCSGGAYDIIICDECHSTD 331 Query: 222 EE--LDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLH 279 L + + + T + V++ +AT + N E+ + + ++ + Sbjct: 332 STTILGIGTVLDQ--AETAGARLVVLATATPPGSVTVPH----PNIEEVALSNTGEIPFY 385 Query: 280 GLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGH 339 G ++ + + +IF S + +EL L+ A+ + Sbjct: 386 GKAIP----------------IEAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRG 429 Query: 340 MKQEERIARYKAFKDFEKRICVSTDVFGRG 369 + + V+TD G Sbjct: 430 LDVSVIPTIGDV-------VVVATDALMTG 452 >2ZJO-A nrPDB Length = 482 Score = 52.3 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 39/270 (14%), Positives = 84/270 (31%), Gaps = 62/270 (22%) Query: 106 AKSGLGKT----AVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVK 161 A +G GK+ A + V+V+ + + P+++ Sbjct: 49 APTGSGKSTKVPAAYA----------AQGYKVLVLNPSVAATLGFGAYMSKAHGVDPNIR 98 Query: 162 TAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVL 221 T V + T I +T G+ + + + DEC Sbjct: 99 TGV--------------RTITTGAPITYSTYGK---FLADGGCSGGAYDIIMCDECHSTD 141 Query: 222 EE--LDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLH 279 L + + + T + V++ +AT + N EI + + ++ + Sbjct: 142 STTILGIGTVLDQ--AETAGARLVVLATATPPGSVTVPH----PNIEEIALSNTGEIPFY 195 Query: 280 GLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGH 339 G ++ ++ + +IF S + +EL L+A A+ + Sbjct: 196 GKAIP----------------IETIKGGRHLIFCHSKKKCDELAAKLSALGIHAVAYYRG 239 Query: 340 MKQEERIARYKAFKDFEKRICVSTDVFGRG 369 + ++ A + V+TD G Sbjct: 240 LD----VSVIPA--SGNV-VVVATDALMTG 262 >4OK6-A nrPDB Length = 464 Score = 52.3 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 39/270 (14%), Positives = 79/270 (29%), Gaps = 62/270 (22%) Query: 106 AKSGLGKT----AVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVK 161 A +G GK+ A + V+V+ + + P+++ Sbjct: 38 APTGSGKSTKVPAAYA----------AQGYKVLVLNPSVAATLGFGAYMSKAHGVDPNIR 87 Query: 162 TAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKV- 220 T V + T I +T G+ + + + DEC Sbjct: 88 TGV--------------RTITTGSPITYSTYGK---FLADGGCSGGAYDIIICDECHSTD 130 Query: 221 -LEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLH 279 L + + + T + V++ +AT + N E+ + ++ + Sbjct: 131 ATSILGIGTVLDQ--AETAGARLVVLATATPPGSV----TVSHPNIEEVALSTTGEIPFY 184 Query: 280 GLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGH 339 G L+ ++ + +IF S + +EL L A A+ + Sbjct: 185 GKAIP----------------LEVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYRG 228 Query: 340 MKQEERIARYKAFKDFEKRICVSTDVFGRG 369 + + VSTD G Sbjct: 229 LDVSVIPTNGDV-------VVVSTDALMTG 251 >3B6E-A nrPDB Length = 216 Score = 52.3 bits (124), Expect = 5e-07, Method: Composition-based stats. Identities = 30/142 (21%), Positives = 49/142 (34%), Gaps = 15/142 (10%) Query: 87 EVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEV---AVVVICNARELA 143 Q ++ G +++ +G GKT V V LD V+V+ N L Sbjct: 36 PYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLV 95 Query: 144 YQIR-NEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATP----GRLKAL 198 Q+ E+ F K + G T + + I+++T L L Sbjct: 96 EQLFRKEFQPFLKKWY--RVIGLSGDTQLKISFP---EVVKSCDIIISTAQILENSLLNL 150 Query: 199 V--REKYIDLSHVKNFVIDECD 218 + + LS +IDEC Sbjct: 151 ENGEDAGVQLSDFSLIIIDECH 172 >3MWY-W nrPDB Length = 800 Score = 51.5 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 29/149 (19%), Positives = 53/149 (35%), Gaps = 5/149 (3%) Query: 290 EREKNRKLAQLLDDLEFN--QVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIA 347 K L QLL L+ + +V+IF + + L L+ + G + +R Sbjct: 554 SSGKMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRI 613 Query: 348 RYKAFKD---FEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKG 404 F + +ST G GI++ + + +D L + RA R G K Sbjct: 614 SIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKN 673 Query: 405 LAISFVSSKEDEEVLAKIQERFDVKIAEF 433 + + +D ++ I E+ Sbjct: 674 HVMVYRLVSKDTVEEEVLERARKKMILEY 702 >5X0Y-O nrPDB Length = 735 Score = 49.6 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 5/116 (4%) Query: 293 KNRKLAQLLDDL--EFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYK 350 K L ++L L ++V+IF + T + + L N + + GH K +ER + Sbjct: 423 KFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLR 482 Query: 351 AFK---DFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTK 403 F +ST G G++++ + I +D Q L RA R G K Sbjct: 483 LFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQK 538 >5HZR-A nrPDB Length = 732 Score = 48.4 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 26/116 (22%), Positives = 46/116 (39%), Gaps = 5/116 (4%) Query: 293 KNRKLAQLLDDL--EFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYK 350 K L ++L ++V++F + T + + L + + G K E+R + Sbjct: 430 KFELLDRILPKYKATGHRVLMFFQMTAIMDIMEDFLRFRGLHYLRLDGTTKSEDRSELLR 489 Query: 351 AFKDFEKR---ICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTK 403 F + +ST G G++++ + I YD Q L RA R G K Sbjct: 490 QFNQPDSPYFMFLLSTRAGGLGLNLQTADTVIIYDSDWNPHQDLQAQDRAHRIGQK 545 >4ERN-A nrPDB Length = 289 Score = 48.4 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 40/117 (34%), Gaps = 10/117 (8%) Query: 292 EKNRKLAQL--LDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARY 349 K R L + +++I+F + E LN ++G Q ER+ Sbjct: 46 NKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKP-----YIYGPTSQGERMQIL 100 Query: 350 KAFKDF-EKRICVSTDVFGRGIDIERINLAINYDLT-NEADQYLHRVGRAGRFGTKG 404 + FK + + V D+ N+ I Q R+GR R KG Sbjct: 101 QNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRA-KKG 156 >2OCA-A nrPDB Length = 510 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 53/366 (14%), Positives = 112/366 (30%), Gaps = 46/366 (12%) Query: 62 TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTL 121 F ++L K E+ P Q+ + + + + + G++ + + L Sbjct: 94 KDFDEWLSKLEIYSGNKRI---EPHWYQKDAVFEGLVNRRRILNLPTSAGRSL--IQALL 148 Query: 122 QQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNK 181 + E +++I L Q+ ++++ + + GG D Sbjct: 149 ARYYLENYEGKILIIVPTTALTTQMADDFVDYRLFSHA--MIKKIGGGASKDD-----KY 201 Query: 182 DTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECD----------------KVLE--- 222 +VV T + V++ S + DEC + + Sbjct: 202 KNDAPVVVGTWQTV---VKQPKEWFSQFGMMMNDECHLATGKSISSIISGLNNCMFKFGL 258 Query: 223 ELDMRRDVQEIFRAT--------PRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEA 274 +R I + P +M +++ I FL+ P E + Sbjct: 259 SGSLRDGKANIMQYVGMFGEIFKPVTTSKLMEDGQVTE--LKINSIFLRYPDEFTTKLKG 316 Query: 275 KLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAI 334 K T + L +R K + + + K + + L+ Sbjct: 317 K-TYQEEIKIITGLSKRNKWIAKLAIKLAQKDENAFVMFKHVSHGKAIFDLIKNEYDKVY 375 Query: 335 TVHGHMKQEERIARYKAFKDFEKRICVST-DVFGRGIDIERINLAINYDLTNEADQYLHR 393 V G + E R ++ + I V++ VF GI ++ ++ + L Sbjct: 376 YVSGEVDTETRNIMKTLAENGKGIIIVASYGVFSTGISVKNLHHVVLAHGVKSKIIVLQT 435 Query: 394 VGRAGR 399 +GR R Sbjct: 436 IGRVLR 441 >2V6J-A nrPDB Length = 431 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 45/307 (14%), Positives = 93/307 (30%), Gaps = 58/307 (18%) Query: 109 GLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGG 168 G GKT VL L + + V + V++ R +A + G Sbjct: 12 GAGKTRR-VLPQLVR-EAVKKRLRTVILAPTRVVASETYEALR----------------G 53 Query: 169 TPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRR 228 PI ++++ T IV + + + + + +++DE L+ + Sbjct: 54 EPIRYMTPAVQSERTGNEIVDFMCHSTFTMKLLQGVRVPNYNLYIMDEAH-FLDPASVAA 112 Query: 229 DVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKL 288 R + D + +AT +P+ +D+E ++ Y + Sbjct: 113 RGYIETRVSMGDAGAIFMTATPPGTTEAFPPS--NSPI---IDEETRIPDKAWNSGYEWI 167 Query: 289 EEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIAR 348 E + FV S + E+ L + + ++ + E Sbjct: 168 TEFDGRTVW--------------FVHSIKQGAEIGTCLQKAGKKVLYLNRKTFESE---- 209 Query: 349 YKAFKDFEKRICVSTDVFGRGIDIERINLA--------------INYDLT--NEADQYLH 392 Y K + ++TD+ G + + + ++ Sbjct: 210 YPKCKSEKWDFVITTDISEMGANFKADRVIDPRKTIKPILLDGRVSMQGPIAITPASAAQ 269 Query: 393 RVGRAGR 399 R GR GR Sbjct: 270 RRGRIGR 276 >5K8T-A nrPDB Length = 458 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 51/323 (15%), Positives = 89/323 (27%), Gaps = 81/323 (25%) Query: 109 GLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGG 168 G GKT VL + + + V++ R +A ++ V + G Sbjct: 34 GAGKTRR-VLPEIVREAIKTR-LRTVILAPTRVVAAEMEEALRGLPVRYMTTAVNVTHSG 91 Query: 169 TPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECD---------- 218 T I D H + RL +R +L +++DE Sbjct: 92 TEI---------VDLMCHATFTS--RLLQPIRVPNYNL-----YIMDEAHFTDPSSIAAR 135 Query: 219 -KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLT 277 + ++M ATP + PI ++ P + +T Sbjct: 136 GYISTRVEMGEAAAIFMTATPPGTRDA-----FPDSNSPIMDTEVEVPERAWSSGFDWVT 190 Query: 278 LHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVH 337 H + + FV S NE+ L + I + Sbjct: 191 DHS--------------------------GKTVWFVPSVRNGNEIAACLTKAGKRVIQLS 224 Query: 338 GHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLA--------INYD------- 382 + E ++ K E V+TD+ G + + + + D Sbjct: 225 RKTFETE----FQKTKHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILA 280 Query: 383 --LTNEADQYLHRVGRAGRFGTK 403 + R GR GR K Sbjct: 281 GPMPVTHASAAQRRGRIGRNPNK 303 >5JXT-B nrPDB Length = 349 Score = 45.3 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 51/141 (36%), Gaps = 5/141 (3%) Query: 293 KNRKLAQLLDDLEFN--QVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYK 350 K L +LL ++ +V+IF + + + L + + G E+RIA Sbjct: 86 KMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYKYCRIDGSTAHEDRIAAID 145 Query: 351 AFK---DFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAI 407 + + ++T G GI++ ++ I YD L + RA R G + Sbjct: 146 EYNKPGSDKFIFLLTTRAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQTKQVV 205 Query: 408 SFVSSKEDEEVLAKIQERFDV 428 + ++ ++ Sbjct: 206 VYRFVTDNAIEEKVLERAAQK 226 >5JXR-A nrPDB Length = 723 Score = 45.3 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 51/141 (36%), Gaps = 5/141 (3%) Query: 293 KNRKLAQLLDDLEFN--QVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYK 350 K L +LL ++ +V+IF + + + L + + G E+RIA Sbjct: 411 KMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYKYCRIDGSTAHEDRIAAID 470 Query: 351 AFK---DFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAI 407 + + ++T G GI++ ++ I YD L + RA R G + Sbjct: 471 EYNKPGSDKFIFLLTTRAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQTKQVV 530 Query: 408 SFVSSKEDEEVLAKIQERFDV 428 + ++ ++ Sbjct: 531 VYRFVTDNAIEEKVLERAAQK 551 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 43/243 (17%), Positives = 77/243 (31%), Gaps = 35/243 (14%) Query: 15 NEQEIQIDASKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIHS-TGFKDFLLKPEL 73 NE+E A + G G ATS A K G + T F++ P Sbjct: 49 NEEE----ARQRKRGGRQGGATSERRRRTEAEEDAELLKDEKDGGSAETVFRE---SPPF 101 Query: 74 SRAIID----CGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPG 129 + + G + ++ I + + GLGKT ++ L L + G Sbjct: 102 IQGTMRDYQIAGLNWLISLHENGISGILAD-------EMGLGKTLQ-TIAFLGYLRHIMG 153 Query: 130 EVAV-VVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIV 188 +V L N F K+ P+V V G + D + Sbjct: 154 ITGPHLVTVPKSTL----DNWKREFEKWTPEVNVLVLQGAKEERHQLINDRLVDENFDVC 209 Query: 189 VATPGRLKALVREKYIDLSHV--KNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMF 246 + + ++ + L + +IDE ++ E V +F + ++ Sbjct: 210 ITS----YEMILREKAHLKKFAWEYIIIDEAHRIKNEESSLAQVIRMF----NSRNRLLI 261 Query: 247 SAT 249 + T Sbjct: 262 TGT 264 >2BMF-A nrPDB Length = 451 Score = 44.6 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 43/315 (13%), Positives = 93/315 (29%), Gaps = 71/315 (22%) Query: 109 GLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGG 168 G GKT ++ + ++ + + + +++ R +A ++ G Sbjct: 29 GAGKTKRYLPAIVR--EAIKRGLRTLILAPTRVVAAEMEEALR----------------G 70 Query: 169 TPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVK-----NFVIDECDKVLEE 223 PI ++ + T IV L LS ++ ++DE + Sbjct: 71 LPIRYQTPAIRAEHTGREIV-----DLMCHATFTMRLLSPIRVPNYNLIIMDEAH-FTDP 124 Query: 224 LDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQ 283 + R + + +AT P + P+ +D+E ++ Sbjct: 125 ASIAARGYISTRVEMGEAAGIFMTATPPGSRDPFPQS--NAPI---MDEEREIPERSWNS 179 Query: 284 YYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQE 343 + + + + + + FV S N++ L + I + Sbjct: 180 GHEWVTDFK--------------GKTVWFVPSIKAGNDIAACLRKNGKKVIQLSRKTFDS 225 Query: 344 ERIARYKAFKDFEKRICVSTDVFGRGIDIERINL---------AINYD----------LT 384 E I + + V+TD+ G + + + I D + Sbjct: 226 EYIKT----RTNDWDFVVTTDISEMGANFKAERVIDPRRCMKPVILTDGEERVILAGPMP 281 Query: 385 NEADQYLHRVGRAGR 399 R GR GR Sbjct: 282 VTHSSAAQRRGRVGR 296 >2QEQ-A nrPDB Length = 434 Score = 43.8 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 49/318 (15%), Positives = 90/318 (28%), Gaps = 77/318 (24%) Query: 109 GLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGG 168 G GKT +L + + + + + V+ R +A ++ G Sbjct: 12 GAGKTRR-ILPQIIK-EAINRRLRTAVLAPTRVVAAEMAEALR----------------G 53 Query: 169 TPISKDAELLKNKDTAPHIV----VATPGRLKALVREKYIDLSHV---KNFVIDECDKVL 221 PI + + IV AT + + + V FV+DE Sbjct: 54 LPIRYQTSAVAREHNGNEIVDVMCHAT-------LTHRLMSPHRVPNYNLFVMDEAH--F 104 Query: 222 EELDMRRDVQEIFRATPRDKQVMMF-SATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHG 280 + I + +F +AT P P+ D + ++ Sbjct: 105 TDPASIAARGYISTRVELGEAAAIFMTATPPGTSDPFPES--NAPIS---DLQTEIPDRA 159 Query: 281 LQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHM 340 Y + E + + FV S NE+ L + I ++ Sbjct: 160 WNSGYEWITEY--------------IGKTVWFVPSVKMGNEIALCLQRAGKKVIQLNRKS 205 Query: 341 KQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLA-----------------INYDL 383 + E Y K+ + V+TD+ G + + + + Sbjct: 206 YETE----YPKCKNDDWDFVVTTDISEMGANFKASRVIDSRKSVKPTIITEGEGRVILGE 261 Query: 384 TN--EADQYLHRVGRAGR 399 + A R GR GR Sbjct: 262 PSAVTAASAAQRRGRTGR 279 >5GN1-A nrPDB Length = 366 Score = 43.8 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 35/159 (22%), Positives = 68/159 (42%), Gaps = 16/159 (10%) Query: 293 KNRKLAQLLDDL---EFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARY 349 K L +LL + + +V+IF T + L +L+ ++ + + G + +R Sbjct: 186 KIDALKKLLKTIIVDKQEKVLIFSLFTQVLDILEMVLSTLDYKFLRLDGSTQVNDRQLLI 245 Query: 350 KAFKDFE-KRI-CVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFG-TKGLA 406 F + + I +ST G GI++ N I +D + RA R G TK + Sbjct: 246 DKFYEDKDIPIFILSTKAGGFGINLVCANNVIIFDQSFNPHDDRQAADRAHRVGQTKEVN 305 Query: 407 ISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYLN 445 I+ + +K+ I+E KI + + + +Y++ Sbjct: 306 ITTLITKDS------IEE----KIHQLAKNKLALDSYIS 334 >2WV9-A nrPDB Length = 673 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 44/312 (14%), Positives = 90/312 (28%), Gaps = 65/312 (20%) Query: 109 GLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGG 168 G GKT +L + + D + + V+ R +A ++ + + AV Sbjct: 251 GAGKTRR-ILPQIIK-DAIQKRLRTAVLAPTRVVAAEMAEALR--GLPVRYLTPAV---- 302 Query: 169 TPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRR 228 ++ + D H + RL + +R +L FV+DE Sbjct: 303 ---QREHSGNEIVDVMCHATLT--HRLMSPLRVPNYNL-----FVMDEAH-------FTD 345 Query: 229 DVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKL 288 P + AT + F+ + Sbjct: 346 ---------PASIAARGYIATRVEAGEA-AAIFMTA-----TPPGTSDPFPDTNSPVHDV 390 Query: 289 EEREKNRKLAQLLDDLEFN--QVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERI 346 +R + + + + + FV S +NE+ + L + I ++ E Sbjct: 391 SSEIPDRAWSSGFEWITDYAGKTVWFVASVKMSNEIAQCLQRAGKRVIQLNRKSYDTE-- 448 Query: 347 ARYKAFKDFEKRICVSTDVFGRGIDIERINLA-----------------INYDLTN--EA 387 Y K+ + ++TD+ G + + + + + + Sbjct: 449 --YPKCKNGDWDFVITTDISEMGANFGASRVIDCRKSVKPTILDEGEGRVILSVPSAITS 506 Query: 388 DQYLHRVGRAGR 399 R GR GR Sbjct: 507 ASAAQRRGRVGR 518 >2V8O-A nrPDB Length = 444 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 44/312 (14%), Positives = 90/312 (28%), Gaps = 65/312 (20%) Query: 109 GLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGG 168 G GKT +L + + D + + V+ R +A ++ + + AV Sbjct: 22 GAGKTRR-ILPQIIK-DAIQKRLRTAVLAPTRVVAAEMAEALR--GLPVRYLTPAV---- 73 Query: 169 TPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRR 228 ++ + D H + RL + +R +L FV+DE Sbjct: 74 ---QREHSGNEIVDVMCHATLT--HRLMSPLRVPNYNL-----FVMDEAH-------FTD 116 Query: 229 DVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKL 288 P + AT + F+ + Sbjct: 117 ---------PASIAARGYIATRVEAGEA-AAIFMTA-----TPPGTSDPFPDTNSPVHDV 161 Query: 289 EEREKNRKLAQLLDDLEFN--QVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERI 346 +R + + + + + FV S +NE+ + L + I ++ E Sbjct: 162 SSEIPDRAWSSGFEWITDYAGKTVWFVASVKMSNEIAQCLQRAGKRVIQLNRKSYDTE-- 219 Query: 347 ARYKAFKDFEKRICVSTDVFGRGIDIERINLA-----------------INYDLTN--EA 387 Y K+ + ++TD+ G + + + + + + Sbjct: 220 --YPKCKNGDWDFVITTDISEMGANFGASRVIDCRKSVKPTILDEGEGRVILSVPSAITS 277 Query: 388 DQYLHRVGRAGR 399 R GR GR Sbjct: 278 ASAAQRRGRVGR 289 >3BXZ-A nrPDB Length = 471 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 42/294 (14%), Positives = 94/294 (31%), Gaps = 43/294 (14%) Query: 103 LCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKT 162 + + ++G GKT L L+ + G+ VV N LA + +++ + Sbjct: 101 IAEMRTGEGKTLTATLPA--YLNALTGKGVHVVTVNDY-LAQRDAENNRPLFEFL-GLTV 156 Query: 163 AVFYGGTPISKDAELLKNKDTAPHIVVATPGRL-KALVREKY------IDLSHVKNFVID 215 + G P E A I T +R+ + ++D Sbjct: 157 GINLPGMPAPAKREA-----YAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVD 211 Query: 216 ECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATL---------------SQEIRPICRR 260 E D +L + + + + Q + S T + + Sbjct: 212 EVDSIL-----IDEARTPLIISGAN-QTLA-SITFQNYFRLYEKLAGMTGTADTEAFEFS 264 Query: 261 FLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFN--QVIIFVKSTTR 318 + + V + L + + E EK + + + + + V++ S + Sbjct: 265 SIYKLDTVVVPTNRPMIRKDLPDL-VYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEK 323 Query: 319 ANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDI 372 + ++ L + ++ E +A + + ++T++ GRG DI Sbjct: 324 SELVSNELTKAGIKHNVLNAKFHANEAAIVAQA--GYPAAVTIATNMAGRGTDI 375 >1TF2-A nrPDB Length = 844 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 29/145 (20%), Positives = 52/145 (35%), Gaps = 11/145 (7%) Query: 304 LEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVST 363 + V++ + + ++KLL P ++ + E +A + + ++T Sbjct: 430 MTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGA--VTIAT 487 Query: 364 DVFGRGIDIERINLAINYDLTNEADQYLHRV--------GRAGRFGTKGLAISFVSSKED 415 ++ GRG DI+ H GR+GR G G+ F S ED Sbjct: 488 NMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGI-TQFYLSMED 546 Query: 416 EEVLAKIQERFDVKIAEFPEEGIDP 440 E + ER + F + P Sbjct: 547 ELMRRFGAERTMAMLDRFGMDDSTP 571 Score = 38.0 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 17/136 (12%) Query: 95 QSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFS 154 ++H + + + K+G GKT L L+ + G+ VV N LA + + Sbjct: 93 VALHDGN-IAEMKTGEGKTLTSTLPV--YLNALTGKGVHVVTVNEY-LA---SRDAEQMG 145 Query: 155 KYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRL-KALVR------EKYIDLS 207 K + V G ++ ++ K + A I +T L +R ++ + Sbjct: 146 KIFEFLGLTV---GLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQR 202 Query: 208 HVKNFVIDECDKVLEE 223 + VIDE D +L + Sbjct: 203 PLHFAVIDEVDSILID 218 >5EUL-A nrPDB Length = 836 Score = 42.6 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 29/145 (20%), Positives = 52/145 (35%), Gaps = 11/145 (7%) Query: 304 LEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVST 363 + V++ + + ++KLL P ++ + E +A + + ++T Sbjct: 427 MTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGA--VTIAT 484 Query: 364 DVFGRGIDIERINLAINYDLTNEADQYLHRV--------GRAGRFGTKGLAISFVSSKED 415 ++ GRG DI+ H GR+GR G G+ F S ED Sbjct: 485 NMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGI-TQFYLSMED 543 Query: 416 EEVLAKIQERFDVKIAEFPEEGIDP 440 E + ER + F + P Sbjct: 544 ELMRRFGAERTMAMLDRFGMDDSTP 568 Score = 38.0 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 17/136 (12%) Query: 95 QSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFS 154 ++H + + + K+G GKT L L+ + G+ VV N LA + + Sbjct: 90 VALHDGN-IAEMKTGEGKTLTSTLPV--YLNALTGKGVHVVTVNEY-LA---SRDAEQMG 142 Query: 155 KYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRL-KALVR------EKYIDLS 207 K + V G ++ ++ K + A I +T L +R ++ + Sbjct: 143 KIFEFLGLTV---GLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQR 199 Query: 208 HVKNFVIDECDKVLEE 223 + VIDE D +L + Sbjct: 200 PLHFAVIDEVDSILID 215 >3H1T-A nrPDB Length = 590 Score = 42.6 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 41/114 (35%), Gaps = 11/114 (9%) Query: 297 LAQLLDD-LEFNQVIIFVKSTTRANELTKLLNASNFPAITVH----GHMKQEE------R 345 L + F + I+F A+E+ + LN N H + EE Sbjct: 429 LTDFMKRTDRFAKTIVFCVDQEHADEMRRALNNLNSDLSRKHPDYVARVTSEEGKIGKGH 488 Query: 346 IARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGR 399 ++R++ + I ++ + G+D + + N ++ VGR R Sbjct: 489 LSRFQELETSTPVILTTSQLLTTGVDAPTCKNVVLARVVNSMSEFKQIVGRGTR 542 >1Z6A-A nrPDB Length = 500 Score = 41.5 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 53/121 (43%), Gaps = 11/121 (9%) Query: 288 LEEREKNRKLAQLLDD--LEFNQVIIFVKSTTRANELTKLL-NASNFPAITVHGHMKQEE 344 + K + +++++ E +++ IF + + ++ N ++G + ++E Sbjct: 321 VRRSGKMIRTMEIIEEALDEGDKIAIFTQFVDMGKIIRNIIEKELNTEVPFLYGELSKKE 380 Query: 345 RIARYKAFKDFEKR--ICVSTDVFGRGIDIERINLAINYD------LTNEADQYLHRVGR 396 R F++ I +S G GI++ N I++D + ++A ++R+G+ Sbjct: 381 RDDIISKFQNNPSVKFIVLSVKAGGFGINLTSANRVIHFDRWWNPAVEDQATDRVYRIGQ 440 Query: 397 A 397 Sbjct: 441 T 441 >2JLW-A nrPDB Length = 451 Score = 41.1 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 45/320 (14%), Positives = 85/320 (26%), Gaps = 81/320 (25%) Query: 109 GLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGG 168 G GKT +L ++ + + + + +++ R +A ++ G Sbjct: 29 GAGKTKR-ILPSIVR-EALKRRLRTLILAPTRVVAAEMEEALR----------------G 70 Query: 169 TPISKDAELLKNKDTAPHIVVATPGRLKALV-----REKYIDLSHV---KNFVIDECDKV 220 PI +K+ T IV L+ + + + V V+DE Sbjct: 71 LPIRYQTPAVKSDHTGREIV--------DLMCHATFTTRLLSSTRVPNYNLIVMDEAH-- 120 Query: 221 LEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQN--PLEIFVDDEAKLTL 278 R + M F+ P I ++ + Sbjct: 121 -----FTDPCSVAARGYISTRVEMG----------EAAAIFMTATPPGSIDPFPQSNSPI 165 Query: 279 HGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHG 338 +++ + + + + FV S N++ L S I + Sbjct: 166 EDIEREIPERSWNTGFDWITDY-----QGKTVWFVPSIKAGNDIANCLRKSGKRVIQLSR 220 Query: 339 HMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINL---------AINYDLTN---- 385 E Y K + V+TD+ G + + I D Sbjct: 221 KTFDTE----YPKTKLTDWDFVVTTDISEMGANFRAGRVIDPRRCLKPVILTDGPERVIL 276 Query: 386 ------EADQYLHRVGRAGR 399 R GR GR Sbjct: 277 AGPIPVTPASAAQRRGRIGR 296 >1Z5Z-A nrPDB Length = 271 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 53/121 (43%), Gaps = 11/121 (9%) Query: 288 LEEREKNRKLAQLLDD--LEFNQVIIFVKSTTRANELTKLL-NASNFPAITVHGHMKQEE 344 + K + +++++ E +++ IF + + ++ N ++G + ++E Sbjct: 92 VRRSGKMIRTMEIIEEALDEGDKIAIFTQFVDMGKIIRNIIEKELNTEVPFLYGELSKKE 151 Query: 345 RIARYKAFKDFEKR--ICVSTDVFGRGIDIERINLAINYD------LTNEADQYLHRVGR 396 R F++ I +S G GI++ N I++D + ++A ++R+G+ Sbjct: 152 RDDIISKFQNNPSVKFIVLSVKAGGFGINLTSANRVIHFDRWWNPAVEDQATDRVYRIGQ 211 Query: 397 A 397 Sbjct: 212 T 212 >2WZQ-A nrPDB Length = 619 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 48/324 (14%), Positives = 90/324 (27%), Gaps = 89/324 (27%) Query: 109 GLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGG 168 G GKT +L ++ + + + + +++ R +A ++ G Sbjct: 197 GAGKTKR-ILPSIVR-EALKRRLRTLILAPTRVVAAEMEEALR----------------G 238 Query: 169 TPISKDAELLKNKDTAPHIVVATPGRLKALV-----REKYIDLSHV---KNFVIDECDKV 220 PI +K+ T IV L+ + + + V V+DE Sbjct: 239 LPIRYQTPAVKSDHTGREIV--------DLMCHATFTTRLLSSTRVPNYNLIVMDEAH-- 288 Query: 221 LEELDMRRDV------QEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEA 274 R + + +AT P + +P+E D E Sbjct: 289 -----FTDPCSVAARGYISTRVEMGEAAAIFMTATPPGSTDPFPQS--NSPIE---DIER 338 Query: 275 KLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAI 334 ++ + + + + + + FV S N++ L S I Sbjct: 339 EIPERSWNTGFDWITDYQ--------------GKTVWFVPSIKAGNDIANCLRKSGKRVI 384 Query: 335 TVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINL---------AINYDLTN 385 + E Y K + V+TD+ G + + I D Sbjct: 385 QLSRKTFDTE----YPKTKLTDWDFVVTTDISEMGANFRAGRVIDPRRCLKPVILTDGPE 440 Query: 386 ----------EADQYLHRVGRAGR 399 R GR GR Sbjct: 441 RVILAGPIPVTPASAAQRRGRIGR 464 >1NLZ-A nrPDB Length = 330 Score = 39.2 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 18/115 (15%), Positives = 43/115 (37%), Gaps = 21/115 (18%) Query: 43 NNNNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHG--- 99 N+ + + S + F++ GF + + ++ I G Sbjct: 124 NDETISISIRIPSKTTYPHSFFEE-------------QGFYNLLDNKEQAISAIKDGIAI 170 Query: 100 -TDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRF 153 +V+ +G GKT ++ S ++ + P E ++ I + E+ ++ Y + Sbjct: 171 GKNVIVCGGTGSGKT-TYIKSIMEFI---PKEERIISIEDTEEIVFKHHKNYTQL 221 >1NL3-A nrPDB Length = 922 Score = 38.0 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 21/135 (15%), Positives = 45/135 (33%), Gaps = 14/135 (10%) Query: 268 IFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDL--EFNQVIIFVKSTTRANELTKL 325 + + Q I E K + + + + V+I S R+ L++ Sbjct: 420 VVSIPTNMPMIREDQSDLIYKTEEAKYIAVVDDVAERYAKGQPVLIGTTSVERSEYLSRQ 479 Query: 326 LNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDI---ERINLAIN-- 380 P ++ ++E A + + V+T++ GRG DI ++ + Sbjct: 480 FTKRRIPHNVLNAKYHEQEATIIAVAGRRG--GVTVATNMAGRGTDIVLGGNVDFLTDQR 537 Query: 381 -----YDLTNEADQY 390 D ++Y Sbjct: 538 LRERGLDPVETPEEY 552 Score = 33.0 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 44/134 (32%), Gaps = 28/134 (20%) Query: 103 LCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKT 162 + + K+G GKT VL L+ + G +V N LA + R +++ ++ Sbjct: 128 VAEMKTGEGKTLTCVLPA--YLNALAGNGVHIVTVNDY-LAKRDSEWMGRVHRFL-GLQV 183 Query: 163 AVFYGGTPISKDAELLKNKDTAPHIVVATPG-------------RLKALVREKYIDLSHV 209 V + + I T L LV+ + Sbjct: 184 GVILATMTPDE-----RRVAYNADITYGTNNEFGFDYLRDNMAHSLDDLVQRGH------ 232 Query: 210 KNFVIDECDKVLEE 223 ++DE D +L + Sbjct: 233 HYAIVDEVDSILID 246 >6FWS-A nrPDB Length = 716 Score = 37.6 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 29/73 (39%), Gaps = 7/73 (9%) Query: 98 HGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQ---IRNEYLRFS 154 G + +A +G+GKT +++ + +V+ +A Q + Sbjct: 46 EGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKT---LVVS-TANVALQDQIYSKDLPLLK 101 Query: 155 KYMPDVKTAVFYG 167 K +PD+K +G Sbjct: 102 KIIPDLKFTAAFG 114 >1Z3I-X nrPDB Length = 644 Score = 34.9 bits (79), Expect = 0.062, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 37/103 (35%), Gaps = 3/103 (2%) Query: 307 NQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKR---ICVST 363 ++V++ T + KL + + + G M ++R + F + +S+ Sbjct: 417 DKVVLVSNYTQTLDLFEKLCRNRRYLYVRLDGTMSIKKRAKIVERFNNPSSPEFIFMLSS 476 Query: 364 DVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLA 406 G G+++ N + +D + R R G K Sbjct: 477 KAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTC 519 >3LLM-A nrPDB Length = 235 Score = 34.2 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 36/180 (20%), Positives = 64/180 (35%), Gaps = 17/180 (9%) Query: 90 QHTIPQSIHGTDVLCQAKSGLGKTAV---FVLSTLQQLDPVPGEVAVVVICNARELAYQI 146 + + V+ + +G GKT F+L Q D E +VV R A + Sbjct: 67 SEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRA-AECNIVVTQPRRISAVSV 125 Query: 147 RNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDL 206 E + F + K+ G + ++ L + I+ T G L + + Sbjct: 126 A-ERVAFERGEEPGKSC----GYSVRFESILPR---PHASIMFCTVGVLLRKLEAGIRGI 177 Query: 207 SHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPL 266 SHV ++DE + D V + ++++ SAT+ C F P+ Sbjct: 178 SHV---IVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTS--MFCEYFFNCPI 232 >2V1U-A nrPDB Length = 387 Score = 33.4 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 29/149 (19%), Positives = 50/149 (33%), Gaps = 26/149 (17%) Query: 90 QHTIPQSIHGT---DVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQI 146 + ++ G + L +G GKTAV L L++L+ + V+V A Sbjct: 32 AEVLAPALRGEKPSNALLYGLTGTGKTAVARL-VLRRLEARASSLGVLV-KPIYVNARHR 89 Query: 147 RNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDL 206 Y S V V + G + + E RL ++ L Sbjct: 90 ETPYRVASAIAEAVGVRVPFTGLSVGEVYE-----------------RLV----KRLSRL 128 Query: 207 SHVKNFVIDECDKVLEELDMRRDVQEIFR 235 + V+DE D + + + + I R Sbjct: 129 RGIYIIVLDEIDFLPKRPGGQDLLYRITR 157 >2EBD-A nrPDB Length = 309 Score = 33.0 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 15/115 (13%), Positives = 43/115 (37%), Gaps = 6/115 (5%) Query: 267 EIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLL 326 I + + G ++ ++ +++ + + ++ +S +++ L + Sbjct: 124 FIKSGKAKNVLVIGAEKLSEAVDWEDRSTCVLF----GDGAGAVVVTRSEDKSDILATRM 179 Query: 327 NASNFPAITVHGHMKQEERIARYKAFKDFEKRI-CVSTDVFGR-GIDIERINLAI 379 A +H R+ + FK + + V +V + G+ E ++L I Sbjct: 180 YAEGSLEELLHADNCGYIRMKGRELFKVAVRSMEEVCREVLEKAGVKPEEVSLVI 234 >4M44-A nrPDB Length = 346 Score = 32.6 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 27/139 (19%), Positives = 44/139 (31%), Gaps = 12/139 (8%) Query: 237 TPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRK 296 P F AT++ + + NPL + V + + +K + Sbjct: 143 CPNATSRSGFFATMAWAVPKDNNKTATNPLTVEVPHICTKEEDQITVW--GFHSDDKTQ- 199 Query: 297 LAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIAR-YKAFKDF 355 + L D + F S + FP T G + Q RI Y K Sbjct: 200 MKNLYGDSNPQK---FTSSANGVT-THYVSQIGGFPDQTEDGGLPQSGRIVVDYMVQKPG 255 Query: 356 EKRICVSTDVFGRGIDIER 374 + T V+ RGI + + Sbjct: 256 KTG----TIVYQRGILLPQ 270 >1RRL-A nrPDB Length = 857 Score = 32.6 bits (73), Expect = 0.38, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 28/87 (32%), Gaps = 4/87 (4%) Query: 226 MRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQ--NPLEIFVDDEAKLTLHGLQQ 283 R D ++ + P + SA ++ E R L NP I + Q Sbjct: 335 FRTDGEQALKFPPPKVIQVSKSAWMTDE--EFAREMLAGVNPNLIRCLKDFPPRSKLDSQ 392 Query: 284 YYIKLEEREKNRKLAQLLDDLEFNQVI 310 Y + L L+ L ++ I Sbjct: 393 VYGDHTSQITKEHLEPNLEGLTVDEAI 419 >3A2B-A nrPDB Length = 398 Score = 31.9 bits (71), Expect = 0.63, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 34/109 (31%), Gaps = 12/109 (11%) Query: 225 DMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQY 284 ++ + + +MFSA+++ L+ I + Sbjct: 250 GFVAGDADVIDFLKHNARSVMFSASMTPA---SVASTLKALEII-------QNEPEHIEK 299 Query: 285 YIKLEEREKNRKLAQLLDDLEFNQVI--IFVKSTTRANELTKLLNASNF 331 K + K + L D I IF++S + +TK+L Sbjct: 300 LWKNTDYAKAQLLDHGFDLGATESPILPIFIRSNEKTFWVTKMLQDDGV 348 >6EG3-A nrPDB Length = 621 Score = 31.9 bits (71), Expect = 0.64, Method: Composition-based stats. Identities = 24/136 (17%), Positives = 56/136 (41%), Gaps = 13/136 (9%) Query: 89 QQHTIPQSIHGTDV--LCQAKSGLGKTA--VFVLSTLQQLDPVPGEVAVVVICNARELAY 144 Q S++ ++ + + GLGKT + +++ L + + G ++I L Sbjct: 396 QGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPY--LIIVPLSTL-- 451 Query: 145 QIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYI 204 N F K+ P V + Y GTP + + + + + ++++ T + + + Sbjct: 452 --SNWTYEFDKWAPSV-VKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYII--KDKHIL 506 Query: 205 DLSHVKNFVIDECDKV 220 K ++DE ++ Sbjct: 507 AKIRWKYMIVDEGHRM 522 >3ACB-A nrPDB Length = 181 Score = 31.5 bits (70), Expect = 0.78, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 20/45 (44%), Gaps = 1/45 (2%) Query: 97 IHGTDVLCQAK-SGLGKTAVFVLSTLQQLDPVPGEVAVVVICNAR 140 IHG DV+ G T ++L L+ P VA ++ +R Sbjct: 93 IHGRDVIVVEDIVDTGLTLSYLLDYLEARKPASVRVAALLSKPSR 137 >5K9T-A nrPDB Length = 578 Score = 31.1 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 43/128 (33%), Gaps = 16/128 (12%) Query: 103 LCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKT 162 + + ++G GKT L L+ + G+ VV N LA + +++ + Sbjct: 87 IAEMRTGEGKTLTATLPA--YLNALTGKGVHVVTVNDY-LAQRDAENNRPLFEFL-GLTV 142 Query: 163 AVFYGGTPISKDAELLKNKDTAPHIVVATPGRL-KALVREKY------IDLSHVKNFVID 215 + G P E A I T +R+ + ++D Sbjct: 143 GINLPGMPAPAKREA-----YAADITYGTNNEYGFDYLRDNMAFSPAARVQRKLHYALVD 197 Query: 216 ECDKVLEE 223 E D +L + Sbjct: 198 EVDSILID 205 Score = 31.1 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 37/89 (41%), Gaps = 4/89 (4%) Query: 286 IKLEEREKNRKLAQLLDDLEFN--QVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQE 343 + + E EK + + + + + V++ S ++ ++ L + ++ Sbjct: 415 VYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHAN 474 Query: 344 ERIARYKAFKDFEKRICVSTDVFGRGIDI 372 E +A + + ++T++ GRG DI Sbjct: 475 EAAIVAQA--GYPAAVTIATNMAGRGTDI 501 >6J5T-G nrPDB Length = 852 Score = 31.1 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 17/95 (17%) Query: 247 SATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQY-----YIKLEER--EKN----R 295 S T ++E I R L+N + V D+ L +QQY Y+ + + +KN Sbjct: 221 SQTFTEE--QIMRSILRNLGDASVGDDIGTLLRKIQQYLLGKRYLIVMDDVWDKNLSWWD 278 Query: 296 KLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASN 330 K+ Q L + VI+ TTR+ + K + A + Sbjct: 279 KIYQGLPRGQGGSVIV----TTRSESVAKRVQARD 309 >5H8W-A nrPDB Length = 597 Score = 31.1 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 24/53 (45%), Gaps = 2/53 (3%) Query: 106 AKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMP 158 + +G GKT + + S LQ +V +V N++E Q+ E S M Sbjct: 11 SPTGSGKTIMALKSALQYSSERKLKVLYLVRTNSQE--EQVIKELRSLSSTMK 61 >5B55-A nrPDB Length = 340 Score = 30.7 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 27/77 (35%), Gaps = 4/77 (5%) Query: 288 LEEREKNRKLAQLLDDLEFNQV--IIFVKSTTRANELTKLLNASNFPAITVHGHMKQEER 345 +++R L + + E + I+ S + + P I EER Sbjct: 49 IKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEER 108 Query: 346 IARYKAFKDFEKRICVS 362 + ++F K I VS Sbjct: 109 KSLIRSF--GAKIILVS 123 >2FSI-A nrPDB Length = 853 Score = 30.7 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 43/128 (33%), Gaps = 16/128 (12%) Query: 103 LCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKT 162 + + ++G GKT L L+ + G+ VV N LA + +++ + Sbjct: 91 IAEMRTGEGKTLTATLPA--YLNALTGKGVHVVTVNDY-LAQRDAENNRPLFEFL-GLTV 146 Query: 163 AVFYGGTPISKDAELLKNKDTAPHIVVATPGRL-KALVREKY------IDLSHVKNFVID 215 + G P E A I T +R+ + ++D Sbjct: 147 GINLPGMPAPAKREA-----YAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVD 201 Query: 216 ECDKVLEE 223 E D +L + Sbjct: 202 EVDSILID 209 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 37/89 (41%), Gaps = 4/89 (4%) Query: 286 IKLEEREKNRKLAQLLDDLEFN--QVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQE 343 + + E EK + + + + + V++ S ++ ++ L + ++ Sbjct: 419 VYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHAN 478 Query: 344 ERIARYKAFKDFEKRICVSTDVFGRGIDI 372 E +A + + ++T++ GRG DI Sbjct: 479 EAAIVAQA--GYPAAVTIATNMAGRGTDI 505 >6EJ5-A nrPDB Length = 637 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 31/97 (31%), Gaps = 2/97 (2%) Query: 65 KDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQL 124 +D ++K +L + G + Q + + + L Q G GKT Sbjct: 174 EDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLA 233 Query: 125 DPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVK 161 G V+V + Q+ + + + + Sbjct: 234 RQGNGP--VLVCAPSNIAVDQLTEKIHQTGLKVVRLC 268 >2WJV-A nrPDB Length = 800 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 31/97 (31%), Gaps = 2/97 (2%) Query: 65 KDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQL 124 +D ++K +L + G + Q + + + L Q G GKT Sbjct: 337 EDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLA 396 Query: 125 DPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVK 161 G V+V + Q+ + + + + Sbjct: 397 RQGNGP--VLVCAPSNIAVDQLTEKIHQTGLKVVRLC 431 >4HZU-A nrPDB Length = 279 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 18/120 (15%), Positives = 38/120 (31%), Gaps = 2/120 (1%) Query: 210 KNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIF 269 K ++DE +L+ R ++ I R + + + + S T + R L Sbjct: 160 KILILDEATSMLDPQG-RIEMLAIVRQLRQQQNLTVISITHDIDEAASADRVLVIDDGRL 218 Query: 270 VDDEAKLTLHGLQQYYIKLEEREKN-RKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNA 328 VD+ + +++ KL L + + L + L+ Sbjct: 219 VDEAVPSQIFERGTQLVEMGLDLPFTEKLKAALRQRGITPPTTYQTAAEMEEWLWQSLSN 278 >1UB3-A nrPDB Length = 220 Score = 30.7 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 57/158 (36%), Gaps = 13/158 (8%) Query: 17 QEIQIDASKAAEAGETGAATSATEGD---NNNNTAAGDKKGSYVGIHSTGFKDFLLKPEL 73 QE ++ A +AA A A A E D + AGD Y+ ++ + + Sbjct: 68 QEKEVKALEAALA----CARGADEVDMVLHLGRAKAGDLD--YLEAEVRAVRE-AVPQAV 120 Query: 74 SRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFV--LSTLQQLDPVPGEV 131 + I++ G+ P E+ + G D L + +G G + ++ L ++ +V Sbjct: 121 LKVILETGYFSPEEIARLAEAAIRGGADFLKTS-TGFGPRGASLEDVALLVRVAQGRAQV 179 Query: 132 AVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGT 169 RE A ++ V GGT Sbjct: 180 KAAGGIRDRETALRMLKAGASRLGTSSGVALVAGEGGT 217 >1SXJ-C nrPDB Length = 340 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 21/56 (37%), Gaps = 3/56 (5%) Query: 165 FYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKV 220 YG + EL + D +V ++K + I K ++DE D + Sbjct: 70 IYGKNYSNMVLELNASDDRGIDVVR---NQIKDFASTRQIFSKGFKLIILDEADAM 122 >3FCY-A nrPDB Length = 346 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 29/88 (32%), Gaps = 17/88 (19%) Query: 215 DECDKVLEELDMRR--DVQEIFRATP---RDKQVMM-------FS---ATLSQEIRPICR 259 D+ D +L + I P D+ +M S A L +R + Sbjct: 170 DDADNMLFRHIFLDTAQLAGIVMNMPEVDEDRVGVMGPSQGGGLSLACAALEPRVRKVVS 229 Query: 260 R--FLQNPLEIFVDDEAKLTLHGLQQYY 285 FL + ++ D AK + Y+ Sbjct: 230 EYPFLSDYKRVWDLDLAKNAYQEITDYF 257 >3AHX-A nrPDB Length = 453 Score = 30.3 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 9/81 (11%) Query: 12 YSDNEQEIQIDA--------SKAAEAGETGAATSATEGDNNNNTAAGDKKGSYVGIHSTG 63 Y + EQ+ QI S +A+ E AA ++G NN KG+Y Sbjct: 208 YRELEQDGQIGITLNLSTCYSNSADE-EDIAAAHRSDGWNNRWFLDAALKGTYPEDMIKI 266 Query: 64 FKDFLLKPELSRAIIDCGFEH 84 F D + PEL + + FE Sbjct: 267 FSDTNIMPELPKELFTEVFET 287 >2B8N-A nrPDB Length = 429 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 27/74 (36%) Query: 274 AKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPA 333 ++ L L++Y I+ E K L + L ++ + +E L F A Sbjct: 222 SEDALKVLEKYGIETSESVKRAILQETPKHLSNVEIHLIGNVQKVCDEAKSLAKEKGFNA 281 Query: 334 ITVHGHMKQEERIA 347 + + E R A Sbjct: 282 EIITTSLDCEAREA 295 >3T0T-A nrPDB Length = 606 Score = 29.6 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 33/197 (16%), Positives = 69/197 (35%), Gaps = 26/197 (13%) Query: 252 QEIRPICRRFLQNPLEIFVD-DEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVI 310 IR + +R L + I +D ++ H ++ I+LE + ++ + Sbjct: 69 DTIRKVAKR-LDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSV 127 Query: 311 IFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGI 370 + + +L + V + ++ + E + +G+ Sbjct: 128 TYENLINDVQVGSYILLDDGLIELQVK-DIDHAKKEVKCDILNSGELK-------NKKGV 179 Query: 371 DIERINLAINYDLTNEADQYLHRVGRAGRFGTKG----LAISFVSSKEDEEVLAKIQERF 426 ++ + + L ++ + RFG K +A SFV D + +I E Sbjct: 180 NLPGVRV----SLPGITEKDAEDI----RFGIKENVDFIAASFVRRPSDVLEIREILEEQ 231 Query: 427 DVKIAEFP----EEGID 439 I+ FP +EGID Sbjct: 232 KANISVFPKIENQEGID 248 >1WA5-C nrPDB Length = 960 Score = 29.2 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 19/36 (52%), Gaps = 4/36 (11%) Query: 231 QEIFRATPRDKQVMMF----SATLSQEIRPICRRFL 262 ++I P Q++ F SAT+ + I+P+ + L Sbjct: 652 EDIQEFIPYVFQIIAFVVEQSATIPESIKPLAQPLL 687 >1YID-B nrPDB Length = 351 Score = 29.2 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 10/75 (13%), Positives = 24/75 (32%), Gaps = 10/75 (13%) Query: 314 KSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIE 373 +E + ++ A+T H ++ R V+ D G+D + Sbjct: 46 NRVRLQDEAELFVLLADVQALTDHFDRPEQVRENVLA----------VALDYLAAGLDPQ 95 Query: 374 RINLAINYDLTNEAD 388 + + + A+ Sbjct: 96 KTTCVVQSAVPELAE 110 >2AOV-A nrPDB Length = 292 Score = 29.2 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 12/95 (12%), Positives = 31/95 (32%), Gaps = 18/95 (18%) Query: 209 VKNFVIDECDKVLEELDMRRDVQEIFRATPRD-----------------KQVMMFSATLS 251 + D+ ++L+ L ++ + ++ + F+AT Sbjct: 196 CQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAP 255 Query: 252 QEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYI 286 ++R + LQ P E K+ + + + Sbjct: 256 PDLRAELGKDLQEPEF-SAKKEGKVLFNNTLSFIV 289 >4XRF-A nrPDB Length = 142 Score = 29.2 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 28/66 (42%) Query: 295 RKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKD 354 ++L + D + +V+I + + + + A N H++ +ER + F+ Sbjct: 74 QELVERYHDKDDRRVVIIELTKKGKARVEEAMTARNEHIAKYFSHLELQEREDLLRLFEK 133 Query: 355 FEKRIC 360 E IC Sbjct: 134 LETIIC 139 >3L76-A nrPDB Length = 600 Score = 28.4 bits (62), Expect = 5.9, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 45/127 (35%), Gaps = 25/127 (19%) Query: 88 VQQHT--IPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARE---- 141 +Q I +++ G + L S +GK+ ++ QQ+ P P + ++ + E Sbjct: 19 IQAVAQRIKRTVQGGNSLVVVVSAMGKSTDVLVDLAQQISPNPCRREMDMLLSTGEQVSI 78 Query: 142 ----LAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKA 197 LA Q E + + + + + ++ P RL+ Sbjct: 79 ALLSLALQ---EIDQPAISLTGAQVGIVTEAEHSRARILEIR------------PDRLEH 123 Query: 198 LVREKYI 204 +RE + Sbjct: 124 HLREGKV 130 >5OPT-P nrPDB Length = 250 Score = 28.0 bits (61), Expect = 8.5, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 21/53 (39%), Gaps = 3/53 (5%) Query: 350 KAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVG---RAGR 399 FK + + ++T V R ++ + E YLH +G RA R Sbjct: 172 DRFKAPKIQRLITTAVKARRAKKAKVAIEKVRKSAEERRAYLHLIGTRRRAAR 224 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.143 0.390 Lambda K H 0.267 0.0442 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,434,220 Number of Sequences: 36641 Number of extensions: 740400 Number of successful extensions: 2942 Number of sequences better than 10.0: 172 Number of HSP's better than 10.0 without gapping: 193 Number of HSP's successfully gapped in prelim test: 81 Number of HSP's that attempted gapping in prelim test: 2232 Number of HSP's gapped (non-prelim): 350 length of query: 446 length of database: 10,336,785 effective HSP length: 100 effective length of query: 346 effective length of database: 6,672,685 effective search space: 2308749010 effective search space used: 2308749010 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.0 bits)