BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q07009 (700 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3DF0-A nrPDB 1445 0.0 1KFU-L nrPDB 1346 0.0 1QXP-A nrPDB 1025 0.0 1MDW-A nrPDB 681 0.0 2NQA-A nrPDB 518 e-147 2NQG-A nrPDB 501 e-142 1ZCM-A nrPDB 496 e-140 2P0R-A nrPDB 397 e-111 6BDT-A nrPDB 360 1e-99 1KFX-S nrPDB 186 3e-47 3BOW-B nrPDB 181 7e-46 4OKH-A nrPDB 179 2e-45 1NP8-A nrPDB 167 2e-41 1JUO-A nrPDB 97 2e-20 5MRA-A nrPDB 96 4e-20 1F4Q-A nrPDB 96 5e-20 1GJY-A nrPDB 95 1e-19 3AAJ-A nrPDB 67 3e-11 2I7A-A nrPDB 61 2e-09 1Y1X-A nrPDB 49 6e-06 3QRX-A nrPDB 44 2e-04 3PM8-A nrPDB 38 0.012 4MVF-A nrPDB 38 0.018 1S6I-A nrPDB 37 0.033 2N7L-C nrPDB 37 0.035 1CLM-A nrPDB 37 0.039 5VLN-A nrPDB 36 0.073 4JWQ-A nrPDB 36 0.074 3U0K-A nrPDB 35 0.11 5UKG-A nrPDB 35 0.13 3K21-A nrPDB 35 0.16 3EK4-A nrPDB 34 0.19 2QFE-A nrPDB 34 0.21 5A2H-A nrPDB 34 0.23 1IJ5-A nrPDB 33 0.33 4OY4-A nrPDB 33 0.39 1DTL-A nrPDB 33 0.43 6HCS-A nrPDB 33 0.45 2N6A-A nrPDB 32 0.64 6O20-F nrPDB 32 0.78 3KF9-A nrPDB 32 0.78 3WFN-B nrPDB 32 0.82 4IL1-A nrPDB 32 0.92 3O4Y-A nrPDB 32 0.93 1ZFS-A nrPDB 32 1.00 5I0I-E nrPDB 32 1.1 2L1W-A nrPDB 32 1.1 3SIA-A nrPDB 32 1.1 4ORC-B nrPDB 32 1.2 5EQX-A nrPDB 32 1.3 2AAO-A nrPDB 32 1.4 4GJF-A nrPDB 31 1.5 3NCG-A nrPDB 31 1.7 4E53-A nrPDB 31 1.8 2F2P-A nrPDB 31 2.1 5UGH-A nrPDB 30 2.8 3AQL-A nrPDB 30 4.4 2BL0-C nrPDB 30 4.8 5LNB-B nrPDB 29 5.5 2TN4-A nrPDB 29 7.7 1ZMZ-A nrPDB 29 7.8 2JNF-A nrPDB 29 8.2 5NIL-D nrPDB 29 8.9 5A9Q-8 nrPDB 29 8.9 2K2A-A nrPDB 28 9.3 >3DF0-A nrPDB Length = 714 Score = 1445 bits (3741), Expect = 0.0, Method: Compositional matrix adjust. Identities = 699/700 (99%), Positives = 699/700 (99%) Query: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGF 60 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGF Sbjct: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGF 60 Query: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI 120 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGD WLLAAIASLTLNEEI Sbjct: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDSWLLAAIASLTLNEEI 120 Query: 121 LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL Sbjct: 121 LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 Query: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC 240 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC Sbjct: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC 240 Query: 241 SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN 300 SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN Sbjct: 241 SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN 300 Query: 301 CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK 360 CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK Sbjct: 301 CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK 360 Query: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQR 420 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQR Sbjct: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQR 420 Query: 421 KMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPG 480 KMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPG Sbjct: 421 KMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPG 480 Query: 481 EYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQ 540 EYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQ Sbjct: 481 EYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQ 540 Query: 541 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL Sbjct: 541 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 Query: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFD 660 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFD Sbjct: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFD 660 Query: 661 NFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 700 NFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL Sbjct: 661 NFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 700 >1KFU-L nrPDB Length = 699 Score = 1346 bits (3483), Expect = 0.0, Method: Compositional matrix adjust. Identities = 653/699 (93%), Positives = 679/699 (97%) Query: 2 AGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFK 61 AGIA KLAKDREAAEGLGSHERAIKYLNQDYE LRNECLEAG LFQDPSFPA+PS+LGFK Sbjct: 1 AGIAAKLAKDREAAEGLGSHERAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFK 60 Query: 62 ELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL 121 ELGPYSSKTRG+ WKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL Sbjct: 61 ELGPYSSKTRGMRWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL 120 Query: 122 ARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL 181 ARVVPL+QSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL Sbjct: 121 ARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL 180 Query: 182 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCS 241 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYEL+KPPPNLFKIIQKAL+KGSLLGCS Sbjct: 181 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS 240 Query: 242 IDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNC 301 IDITSAADSEA+T+QKLVKGHAYSVTGAEEVES+GSLQKLIRIRNPWG+VEWTG+WNDNC Sbjct: 241 IDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNC 300 Query: 302 PSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTKM 361 PSWNT+DPE R LT R EDGEFWMSFSDFLRHYSRLEICNLTPDTLT D+YKKWKLTKM Sbjct: 301 PSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKM 360 Query: 362 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQRK 421 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDED+EDGE GCTFLVGLIQKHRRRQRK Sbjct: 361 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRK 420 Query: 422 MGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPGE 481 MGEDMHTIGFGIYEVPEEL+GQTNIHLSKNFFLT RARERSDTFINLREVLNRFKLPPGE Sbjct: 421 MGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGE 480 Query: 482 YVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQL 541 Y+LVPSTFEP+K+GDFCIRVFSEKKADYQ VDDEIEAN+EE + +E+DI DG RRLFAQL Sbjct: 481 YILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGVRRLFAQL 540 Query: 542 AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILW 601 AGEDAEISAFELQTILRRVLAKR+DIKSDGFSIETCKIMVDMLD DGSGKLGLKEFYILW Sbjct: 541 AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW 600 Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDN 661 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK+PCQLHQVIVARFADD+LIIDFDN Sbjct: 601 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDN 660 Query: 662 FVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 700 FVRCLVRLE LFKIFKQLDPENTGTI+LDLISWL FSVL Sbjct: 661 FVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 699 >1QXP-A nrPDB Length = 900 Score = 1025 bits (2650), Expect = 0.0, Method: Compositional matrix adjust. Identities = 489/703 (69%), Positives = 588/703 (83%), Gaps = 4/703 (0%) Query: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGF 60 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDP+FP + SLGF Sbjct: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPAFPPVSHSLGF 60 Query: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI 120 KELGP SSKT GI+WKRPTE+ ++PQFI+ GATRTDICQGALGD WLLAAIASLTLNE I Sbjct: 61 KELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDSWLLAAIASLTLNETI 120 Query: 121 LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 L RVVP QSFQE YAGIFHFQ WQ+GEWV+VVVDD LPTKDG+L+FVHSA+G+EFWSAL Sbjct: 121 LHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSAL 180 Query: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC 240 LEKAYAK+NG YEALSGG T+E FEDFTGG+ EWY+L+K P +L++II KALE+GSLLGC Sbjct: 181 LEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGC 240 Query: 241 SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN 300 SI+I+ D EA+T++ LV+GHAYSVT A++V G LIR+RNPWG+VEW G W+DN Sbjct: 241 SINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDN 300 Query: 301 CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK 360 WN VDP R L + EDGEFWMSF DF+R +++LEICNLTPD L + + W T Sbjct: 301 SYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDALKSRTLRNWNTTF 360 Query: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEE-EDEDDEDG-ERGCTFLVGLIQKHRRR 418 +G WRRGSTAGGCRNYP TFW+NPQ+ I+LEE +D DD D E GC+FL+ L+QKHRRR Sbjct: 361 YEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEEVDDADDYDSRESGCSFLLALMQKHRRR 420 Query: 419 QRKMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLP 478 +R+ G DM TIGF +Y+VP EL GQ +HL ++FFL +R +S+ FINLREV NR +LP Sbjct: 421 ERRFGRDMETIGFAVYQVPRELAGQP-VHLKRDFFLANASRAQSEHFINLREVSNRIRLP 479 Query: 479 PGEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANI-EEIEANEEDIGDGFRRL 537 PGEY++VPSTFEP+K GDF +R FSEKKA Q +DD+I+AN+ +E +EE+I D F+ L Sbjct: 480 PGEYIVVPSTFEPNKEGDFLLRFFSEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTL 539 Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 F++LAG+D EIS ELQTIL R+++K +D++++GFS+E+C+ MV+++D DG+GKLGL EF Sbjct: 540 FSKLAGDDMEISVKELQTILNRIISKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEF 599 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELII 657 ILW +I+ Y I+R+ D+D+SG+M++YEMR A+E AGFKLPCQLHQVIVARFADDELII Sbjct: 600 NILWNRIRNYLTIFRKFDLDKSGSMSAYEMRMAIEAAGFKLPCQLHQVIVARFADDELII 659 Query: 658 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 700 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL Sbjct: 660 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 702 Score = 179 bits (454), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 83/177 (46%), Positives = 122/177 (68%) Query: 523 IEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 IEANE + FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 722 IEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 781 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 ++D D +GKLG +EF LW I+K+Q IY+ + DRSGT+ S E+ A E AGF L + Sbjct: 782 VMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFETDRSGTIGSNELPGAFEAAGFHLNQHI 841 Query: 643 HQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ F+ LD TG IQ+++ WL ++ Sbjct: 842 YSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEWLQLTM 898 >1MDW-A nrPDB Length = 328 Score = 681 bits (1758), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/328 (99%), Positives = 327/328 (99%) Query: 19 GSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRP 78 GSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRP Sbjct: 1 GSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRP 60 Query: 79 TEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGI 138 TEICADPQFIIGGATRTDICQGALGD WLLAAIASLTLNEEILARVVPLDQSFQENYAGI Sbjct: 61 TEICADPQFIIGGATRTDICQGALGDSWLLAAIASLTLNEEILARVVPLDQSFQENYAGI 120 Query: 139 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG 198 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG Sbjct: 121 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG 180 Query: 199 ATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKL 258 ATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKL Sbjct: 181 ATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKL 240 Query: 259 VKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTER 318 VKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTER Sbjct: 241 VKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTER 300 Query: 319 QEDGEFWMSFSDFLRHYSRLEICNLTPD 346 QEDGEFWMSFSDFLRHYSRLEICNLTPD Sbjct: 301 QEDGEFWMSFSDFLRHYSRLEICNLTPD 328 >2NQA-A nrPDB Length = 326 Score = 518 bits (1335), Expect = e-147, Method: Compositional matrix adjust. Identities = 235/323 (72%), Positives = 283/323 (87%) Query: 24 AIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEICA 83 A+KYL QD++TLR +CL++G LF+DP FPA PS+LG+K+LGP S +T+GI WKRPTE+C Sbjct: 4 ALKYLGQDFKTLRQQCLDSGVLFKDPEFPACPSALGYKDLGPGSPQTQGIIWKRPTELCP 63 Query: 84 DPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQF 143 PQFI+GGATRTDICQG LGDCWLLAAIASLTLNEE+L RVVP DQ FQENYAGIFHFQF Sbjct: 64 SPQFIVGGATRTDICQGGLGDCWLLAAIASLTLNEELLYRVVPRDQDFQENYAGIFHFQF 123 Query: 144 WQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEG 203 WQYGEWVEVV+DDRLPTK+G+LLF+HS +G+EFWSALLEKAYAK+NGCYEAL+GG+T EG Sbjct: 124 WQYGEWVEVVIDDRLPTKNGQLLFLHSEQGNEFWSALLEKAYAKLNGCYEALAGGSTVEG 183 Query: 204 FEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGHA 263 FEDFTGGI+E+Y+L+KPP NL++II+KAL GSLLGCSID+ SAA++EA+T QKLVK HA Sbjct: 184 FEDFTGGISEFYDLKKPPANLYQIIRKALCAGSLLGCSIDVYSAAEAEAITSQKLVKSHA 243 Query: 264 YSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQEDGE 323 YSVTG EEV G +KLIR+RNPWG+VEW+G W+D+ P WN +DP + L ++ EDGE Sbjct: 244 YSVTGVEEVNFQGHPEKLIRLRNPWGEVEWSGAWSDDAPEWNHIDPRRKEELDKKVEDGE 303 Query: 324 FWMSFSDFLRHYSRLEICNLTPD 346 FWMS SDF+R +SRLEICNL+PD Sbjct: 304 FWMSLSDFVRQFSRLEICNLSPD 326 >2NQG-A nrPDB Length = 339 Score = 501 bits (1290), Expect = e-142, Method: Compositional matrix adjust. Identities = 233/330 (70%), Positives = 272/330 (82%) Query: 17 GLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWK 76 GLG HE AIKYL QDYE LR CL+ G LFQD +FP + SLGFKELGP SSKT GI+WK Sbjct: 2 GLGRHENAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWK 61 Query: 77 RPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYA 136 RPTE+ ++PQFI+ GATRTDICQGALGDCWLLAAIASLTLNE IL RVVP QSFQE YA Sbjct: 62 RPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYA 121 Query: 137 GIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALS 196 GIFHFQ WQ+GEWV+VVVDD LPTKDG+L+FVHSA+G+EFWSALLEKAYAK+NG YEALS Sbjct: 122 GIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALS 181 Query: 197 GGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQ 256 GG T+E FEDFTGG+ EWY+L+K P +L++II KALE+GSLLGCSI+I+ D EA+T++ Sbjct: 182 GGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFK 241 Query: 257 KLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLT 316 LV+GHAYSVT A++V G LIR+RNPWG+VEW G W+DN WN VDP R L Sbjct: 242 NLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLR 301 Query: 317 ERQEDGEFWMSFSDFLRHYSRLEICNLTPD 346 + EDGEFWMSF DF+R +++LEICNLTPD Sbjct: 302 VKMEDGEFWMSFRDFIREFTKLEICNLTPD 331 >1ZCM-A nrPDB Length = 321 Score = 496 bits (1277), Expect = e-140, Method: Compositional matrix adjust. Identities = 228/320 (71%), Positives = 270/320 (84%) Query: 24 AIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEICA 83 AIKYL QDYE LR CL++G LF+D +FP +P SLG+K+LGP SSKT GI+WKRPTE+ + Sbjct: 2 AIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLS 61 Query: 84 DPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQF 143 +PQFI+ GATRTDICQGALGDCWLLAAIASLTLN+ +L RVVP QSFQ YAGIFHFQ Sbjct: 62 NPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQL 121 Query: 144 WQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEG 203 WQ+GEWV+VVVDD LP KDG+L+FVHSAEG+EFWSALLEKAYAK+NG YEALSGG+T+E Sbjct: 122 WQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEA 181 Query: 204 FEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGHA 263 FEDFTGG+ EWYELRK P +L++II KALE+GSLLGCSIDI+S D EA+T++KLVKGHA Sbjct: 182 FEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHA 241 Query: 264 YSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQEDGE 323 YSVTGA++V G + LIR+RNPWG+VEWTG W+D+ WN VDP R L + EDGE Sbjct: 242 YSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGE 301 Query: 324 FWMSFSDFLRHYSRLEICNL 343 FWMSF DF+R ++RLEICNL Sbjct: 302 FWMSFRDFMREFTRLEICNL 321 >2P0R-A nrPDB Length = 333 Score = 397 bits (1021), Expect = e-111, Method: Compositional matrix adjust. Identities = 191/326 (58%), Positives = 237/326 (72%), Gaps = 6/326 (1%) Query: 23 RAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEIC 82 R Q +E +R ECL+ G LF+D FPA SSL + E WKRP EI Sbjct: 13 RITHSSGQSFEQMRQECLQRGTLFEDADFPASNSSLFYSE-----RPQIPFVWKRPGEIV 67 Query: 83 ADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQ 142 +P+FI+GGATRTDICQG LGDCWLLAAIASLTLN++ LARV+P DQSF YAGIFHFQ Sbjct: 68 KNPEFILGGATRTDICQGELGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIFHFQ 127 Query: 143 FWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTE 202 FWQ+ EW++VV+DDRLPT L+F+HSA+ +EFWSALLEKAYAK+NG YEAL GG+ E Sbjct: 128 FWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIE 187 Query: 203 GFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGH 262 EDFTGG+AE ++ ++ P N ++I++KAL++GSLLGC ID SAA+SEA T L+KGH Sbjct: 188 AMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCFIDTRSAAESEARTPFGLIKGH 247 Query: 263 AYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQ-ED 321 AYSVTG ++V G +LIRIRNPWGQVEW G W+D+ P W +V P + L +D Sbjct: 248 AYSVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSDSSPEWRSVGPAEQKRLCHTALDD 307 Query: 322 GEFWMSFSDFLRHYSRLEICNLTPDT 347 GEFWM+F DF H+ ++EICNLTPD Sbjct: 308 GEFWMAFKDFKAHFDKVEICNLTPDA 333 >6BDT-A nrPDB Length = 382 Score = 360 bits (924), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 186/364 (51%), Positives = 235/364 (64%), Gaps = 54/364 (14%) Query: 32 YETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEICADPQFIIGG 91 +E L +CLE L+ DP FP +SL + + P WKRP EIC +P+FII G Sbjct: 16 FEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQ-----FVWKRPPEICENPRFIIDG 70 Query: 92 ATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQFWQYGEWVE 151 A RTDICQG LGD W LAAIA LTLN+ +L RV+P DQSF ENYAGIFHFQFW+YGEWV+ Sbjct: 71 ANRTDICQGELGDSWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVD 130 Query: 152 VVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGI 211 VV+DD LPT + +L+F S +EFWSALLEKAYAK++G YEAL GG TTE EDFTGG+ Sbjct: 131 VVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGV 190 Query: 212 AEWYELRKPPPNLFKIIQKALEKGSLLGCSIDI-------TSAA---------------- 248 AE++E+R P +++KI++KA+E+GSL+GCSID TS + Sbjct: 191 AEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMD 250 Query: 249 -----DSE---------------AVTYQK-----LVKGHAYSVTGAEEVESSGSLQKLIR 283 DS+ V Y+ LV+GHAYSVTG +EV G KL+R Sbjct: 251 NSLLQDSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVR 310 Query: 284 IRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTER-QEDGEFWMSFSDFLRHYSRLEICN 342 +RNPWGQVEW G W+D W+ VD + +A L + EDGEFWMS+ DF+ H+++LEICN Sbjct: 311 LRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICN 370 Query: 343 LTPD 346 LT D Sbjct: 371 LTAD 374 >1KFX-S nrPDB Length = 184 Score = 186 bits (472), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 87/177 (49%), Positives = 125/177 (70%) Query: 523 IEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 IEANE + FRRLFAQLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 6 IEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 65 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 ++D D +GKLG +EF LW I+++Q IY++ D DRSGT+ S E+ A E AGF L L Sbjct: 66 VMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHL 125 Query: 643 HQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ FK LD + TG IQ+++ WL ++ Sbjct: 126 YNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 182 >3BOW-B nrPDB Length = 184 Score = 181 bits (460), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 84/177 (47%), Positives = 122/177 (68%) Query: 523 IEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 IEANE + FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 6 IEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 65 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 ++D D +GKLG +EF LW I+K+Q IY+ D DRSGT+ S E+ A E AGF L + Sbjct: 66 VMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHI 125 Query: 643 HQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ F+ LD TG IQ+++ WL ++ Sbjct: 126 YSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEWLQLTM 182 >4OKH-A nrPDB Length = 189 Score = 179 bits (455), Expect = 2e-45, Method: Composition-based stats. Identities = 79/166 (47%), Positives = 120/166 (72%) Query: 534 FRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLG 593 FR +F Q+AG+D EI A EL+ +L V+ K +D+K+ GF++E+C+ M+ ++D DGSGKL Sbjct: 14 FRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLN 73 Query: 594 LKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADD 653 L+EF+ LW KI+ +QKI++ D D+SGT+NSYEMR A+ +AGF L QL+ +I R+AD Sbjct: 74 LQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADK 133 Query: 654 ELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 + IDFD+F+ C VRLE +F+ F D + G I+L+++ WL ++ Sbjct: 134 HMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTM 179 >1NP8-A nrPDB Length = 159 Score = 167 bits (422), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 78/158 (49%), Positives = 111/158 (70%) Query: 523 IEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 IEANE + FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 2 IEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 61 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 ++D D +GKLG +EF LW I+K+Q IY+ D DRSGT+ S E+ A E AGF L + Sbjct: 62 VMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHI 121 Query: 643 HQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLD 680 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ F+ LD Sbjct: 122 YSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLD 159 >1JUO-A nrPDB Length = 198 Score = 97.1 bits (240), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 55/154 (35%), Positives = 84/154 (54%), Gaps = 8/154 (5%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKS--DGFSIETCKIMVDMLDEDGSGKLGLK 595 FA +AG+D +I A ELQ L + I F++ETC++MV MLD D SG +G Sbjct: 39 FAAVAGQDGQIDADELQRCL-----TQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFN 93 Query: 596 EFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDEL 655 EF LW + +++ + D DRSGT++ E++KAL GF+L Q I R++ + Sbjct: 94 EFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGK 153 Query: 656 IIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQL 689 I FD+++ C V+L L F++ D G + Sbjct: 154 IT-FDDYIACCVKLRALTDSFRRRDTAQQGVVNF 186 >5MRA-A nrPDB Length = 167 Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 55/154 (35%), Positives = 84/154 (54%), Gaps = 8/154 (5%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKS--DGFSIETCKIMVDMLDEDGSGKLGLK 595 FA +AG+D +I A ELQ L + I F++ETC++MV MLD D SG +G Sbjct: 8 FAAVAGQDGQIDADELQRCL-----TQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFN 62 Query: 596 EFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDEL 655 EF LW + +++ + D DRSGT++ E++KAL GF+L Q I R++ + Sbjct: 63 EFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGK 122 Query: 656 IIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQL 689 I FD+++ C V+L L F++ D G + Sbjct: 123 IT-FDDYIACCVKLRALTDSFRRRDTAQQGVVNF 155 >1F4Q-A nrPDB Length = 165 Score = 95.9 bits (237), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 53/149 (35%), Positives = 85/149 (57%), Gaps = 4/149 (2%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 F+ +AG+D E+ A ELQ L + + FS+ETC+IM+ MLD D +GK+G F Sbjct: 6 FSAVAGQDGEVDAEELQRCLTQ---SGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAF 62 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELII 657 LW + +++ + +D D SGT+ +E+R+A+ G++L Q IV R++ + I Sbjct: 63 KELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIF 122 Query: 658 DFDNFVRCLVRLEILFKIFKQLDPENTGT 686 FD++V C V+L L FK+ D G+ Sbjct: 123 -FDDYVACCVKLRALTDFFKKRDHLQQGS 150 >1GJY-A nrPDB Length = 167 Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 55/154 (35%), Positives = 83/154 (53%), Gaps = 8/154 (5%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKS--DGFSIETCKIMVDMLDEDGSGKLGLK 595 FA +AG+D +I A ELQ L + I F++ETC++MV MLD D SG +G Sbjct: 8 FASVAGQDGQIDADELQRCL-----TQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFN 62 Query: 596 EFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDEL 655 EF LW + +++ + D DRSGT++ E++KAL GF+L Q I R++ Sbjct: 63 EFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYSTSGK 122 Query: 656 IIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQL 689 I FD+++ C V+L L F++ D G + Sbjct: 123 IT-FDDYIACCVKLRALTDSFRRRDSAQQGMVNF 155 >3AAJ-A nrPDB Length = 167 Score = 66.6 bits (161), Expect = 3e-11, Method: Composition-based stats. Identities = 38/132 (28%), Positives = 72/132 (54%), Gaps = 5/132 (3%) Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631 F+ T + ++ M D + + EF +W I +Q ++R D D SG ++ E+++AL Sbjct: 38 FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 97 Query: 632 EEAGFKLPCQLHQVIVARF-ADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLD 690 +G++L Q H +++ +F I FD+F++ + L+ L IF++ D + G IQ+ Sbjct: 98 --SGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 155 Query: 691 LISWLS--FSVL 700 +LS FS++ Sbjct: 156 YEQYLSMVFSIV 167 >2I7A-A nrPDB Length = 174 Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 42/161 (26%), Positives = 83/161 (51%), Gaps = 8/161 (4%) Query: 541 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 L ++I A +LQ +L + L D FS++ C+ +V +++ +G+L +EF L Sbjct: 14 LVPRGSDIDATQLQGLLNQELLTGP--PGDMFSLDECRSLVALMELKVNGRLDQEEFARL 71 Query: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA----GFKLPCQLHQVIVARFADDELI 656 W ++ YQ +++++ G + S ++ KA+E G + +L ++ R++D Sbjct: 72 WKRLVHYQHVFQKVQTS-PGVLLSSDLWKAIENTDFLRGIFISRELLHLVTLRYSDSVGR 130 Query: 657 IDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSF 697 + F + V L+RLE + K F+ L + G + L + W+S Sbjct: 131 VSFPSLVCFLMRLEAMAKTFRNLSKDGKG-LYLTEMEWMSL 170 >1Y1X-A nrPDB Length = 191 Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 33/129 (25%), Positives = 66/129 (51%), Gaps = 1/129 (0%) Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631 FS+ T + ++ M D++ SG++ EF L I ++ +R+ D G ++S E+R AL Sbjct: 60 FSLATTEKLLHMYDKNHSGEITFDEFKDLHHFILSMREGFRKRDSSGDGRLDSNEVRAAL 119 Query: 632 EEAGFKLPCQLHQVIVARFADDEL-IIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLD 690 +G+++ Q Q ++ +F + FD++V + + + +F D E TG + Sbjct: 120 LSSGYQVSEQTFQALMRKFDRQRRGSLGFDDYVELSIFVCRVRNVFAFYDRERTGQVTFT 179 Query: 691 LISWLSFSV 699 +++ SV Sbjct: 180 FDTFIGGSV 188 >3QRX-A nrPDB Length = 169 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 8/100 (8%) Query: 575 ETCKIMVDMLDEDGSGKLGLKEFYILWT-------KIQKYQKIYREIDVDRSGTMNSYEM 627 E K M+ +D+DGSG + +EF + T ++ K +R D D SGT+ ++ Sbjct: 64 EEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDL 123 Query: 628 RKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFVRCL 666 R+ +E G L +L ++I +D+ ID D F+R + Sbjct: 124 RRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIM 163 >3PM8-A nrPDB Length = 197 Score = 38.1 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 7/95 (7%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF-KLPCQLHQVIVARFADDELIIDFDN 661 +I + I+ +DVD SGT++S E+ L++ G+ K+P +HQV+ ++ I + + Sbjct: 55 EINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTD 114 Query: 662 FV------RCLVRLEILFKIFKQLDPENTGTIQLD 690 F+ + ++ E+ FK D + G I ++ Sbjct: 115 FLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVE 149 >4MVF-A nrPDB Length = 506 Score = 37.7 bits (86), Expect = 0.018, Method: Compositional matrix adjust. Identities = 25/96 (26%), Positives = 50/96 (52%), Gaps = 7/96 (7%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF-KLPCQLHQVIVARFADDELIIDFD 660 +I + I+ +DVD SGT++S E+ L++ G+ K+P +HQV+ ++ I + Sbjct: 357 VEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYT 416 Query: 661 NFV------RCLVRLEILFKIFKQLDPENTGTIQLD 690 +F+ + ++ E+ FK D + G I ++ Sbjct: 417 DFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVE 452 >1S6I-A nrPDB Length = 188 Score = 36.6 bits (83), Expect = 0.033, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 7/97 (7%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL-PCQLHQVIVARFADDELIIDFDN 661 +I +++++ ID D SGT+ E++ L+ G +L ++ ++ A D ID+ Sbjct: 8 EIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGE 67 Query: 662 FVRCLVRL------EILFKIFKQLDPENTGTIQLDLI 692 F+ V L E L F D + +G I LD I Sbjct: 68 FIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEI 104 >2N7L-C nrPDB Length = 141 Score = 36.6 bits (83), Expect = 0.035, Method: Composition-based stats. Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 9/96 (9%) Query: 511 TVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSD 570 ++DD +A +E++ +++ +F L ED IS EL ++R + Sbjct: 15 SMDDIYKAAVEQLTEEQKNEFKAAFDIFV-LGAEDGSISTKELGKVMRML--------GQ 65 Query: 571 GFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQK 606 + E + M+D +DEDGSG + EF ++ + K Sbjct: 66 NPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRXMK 101 >1CLM-A nrPDB Length = 148 Score = 36.6 bits (83), Expect = 0.039, Method: Compositional matrix adjust. Identities = 38/153 (24%), Positives = 72/153 (47%), Gaps = 18/153 (11%) Query: 524 EANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 E EE I + F+ FA + D I+ EL T++R + + + + M++ Sbjct: 3 ELTEEQIAE-FKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAE--------LQDMIN 53 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQ-------KIYREIDVDRSGTMNSYEMRKALEEAG 635 +D DG+G + EF L + K Q + ++ D D +G +++ E+R + G Sbjct: 54 EVDADGNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLG 113 Query: 636 FKLP-CQLHQVIVARFADDELIIDFDNFVRCLV 667 KL ++ ++I D + I+++ FVR +V Sbjct: 114 EKLTDDEVDEMIREADIDGDGHINYEEFVRMMV 146 >5VLN-A nrPDB Length = 120 Score = 35.8 bits (81), Expect = 0.073, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 9/95 (9%) Query: 512 VDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDG 571 +DD +A +E++ +++ +F L ED IS EL ++R + Sbjct: 1 MDDIYKAAVEQLTEEQKNEFKAAFDIFV-LGAEDGSISTKELGKVMRML--------GQN 51 Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQK 606 + E + M+D +DEDGSG + EF ++ + K Sbjct: 52 PTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMK 86 >4JWQ-A nrPDB Length = 199 Score = 35.8 bits (81), Expect = 0.074, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFV 663 +Q+ + ++ +D D G + +++K LE +G KLP ++ +D ID+ F+ Sbjct: 57 LQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEFL 116 Query: 664 -----RCLVRLEILFKIFKQLDPENTGTI 687 R + ++++ F+ D +N G I Sbjct: 117 AAALDRKHLSKKLIYCAFRVFDVDNDGEI 145 Score = 29.3 bits (64), Expect = 6.9, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 5/58 (8%) Query: 579 IMVDMLDEDGSGKLGLKEFYILWTKIQKYQK-----IYREIDVDRSGTMNSYEMRKAL 631 +++D +D DGSG++ EF + K +R DVD G + + E+ L Sbjct: 97 VLLDQIDSDGSGRIDYTEFLAAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHIL 154 >3U0K-A nrPDB Length = 442 Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust. Identities = 28/131 (21%), Positives = 61/131 (46%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D DG G + EF I+ + Sbjct: 318 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGDGTIDFPEFLIMMARK 369 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELI 656 K ++ +R D D +G +++ E+R + G KL ++ ++I D + Sbjct: 370 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 429 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 430 VNYEEFVQMMT 440 >5UKG-A nrPDB Length = 419 Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust. Identities = 27/131 (20%), Positives = 59/131 (45%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D DG G EF + + Sbjct: 295 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGDGTFDFPEFLTMMARK 346 Query: 605 QKY-------QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELI 656 Y ++ +R D D +G + + E+R + + G KL ++ ++I D + Sbjct: 347 MSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQ 406 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 407 VNYEEFVQMMT 417 >3K21-A nrPDB Length = 191 Score = 34.7 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 5/89 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFV 663 ++K + + +D D G + +++K LE+ G KLP ++ +D ID+ F+ Sbjct: 51 VEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFI 110 Query: 664 -----RCLVRLEILFKIFKQLDPENTGTI 687 R + ++++ F+ D +N G I Sbjct: 111 AAALDRKQLSKKLIYCAFRVFDVDNDGEI 139 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 564 REDIKSDGFSIE-TCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQK-----IYREIDVD 617 ++ ++ DG + +++D +D DGSGK+ EF ++ K +R DVD Sbjct: 75 KKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFIAAALDRKQLSKKLIYCAFRVFDVD 134 Query: 618 RSGTMNSYEMRKAL 631 G + + E+ L Sbjct: 135 NDGEITTAELAHIL 148 >3EK4-A nrPDB Length = 451 Score = 34.3 bits (77), Expect = 0.19, Method: Compositional matrix adjust. Identities = 36/171 (21%), Positives = 79/171 (46%), Gaps = 19/171 (11%) Query: 506 KADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKR 564 K D + ++E N + + EE I + F+ F+ + D I+ EL T++R + Sbjct: 289 KEDGNILGHKLEYNTRD-QLTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSLGQNP 346 Query: 565 EDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVD 617 + + + M++ +D DG+G + EF + + K ++ +R D D Sbjct: 347 TEAE--------LQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKD 398 Query: 618 RSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNFVRCLV 667 +G +++ E+R + G KL ++ ++I D + ++++ FV+ + Sbjct: 399 GNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 449 >2QFE-A nrPDB Length = 148 Score = 34.3 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 31/138 (22%) Query: 360 KMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQ 419 +++G W G +AGGC N+ T NP Y +E+ LI+ RQ Sbjct: 26 RINGKWS-GQSAGGCGNFQETHKNNPIYQFHIEKTGPL-------------LIELRGPRQ 71 Query: 420 RKMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPP 479 +++GF + V G H FL + + F L E+ N +P Sbjct: 72 -------YSVGFEVVTV--STLGDPGPH----GFLRKSSGDYRCGFCYL-ELEN---IPS 114 Query: 480 GEYVLVPSTFEPHKNGDF 497 G + ++PSTF P + G F Sbjct: 115 GIFNIIPSTFLPKQEGPF 132 >5A2H-A nrPDB Length = 149 Score = 33.9 bits (76), Expect = 0.23, Method: Compositional matrix adjust. Identities = 23/96 (23%), Positives = 50/96 (52%), Gaps = 8/96 (8%) Query: 580 MVDMLDEDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALE 632 M++ +D DG+G + EF L + K ++ +R D D++G +++ E+R + Sbjct: 52 MINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMT 111 Query: 633 EAGFKLPC-QLHQVIVARFADDELIIDFDNFVRCLV 667 G KL ++ ++I D + I+++ FV+ ++ Sbjct: 112 NLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMM 147 >1IJ5-A nrPDB Length = 323 Score = 33.5 bits (75), Expect = 0.33, Method: Compositional matrix adjust. Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 11/122 (9%) Query: 557 LRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDV 616 L++VLAK D +G K + M++ D G++ + + +R+ID Sbjct: 144 LKQVLAKYADTIPEG----PLKKLFVMVENDTKGRMSYITLVAVANDLAALVADFRKIDT 199 Query: 617 DRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIID--FDNFVR---CLVRLEI 671 + +GT++ E R+ GF Q + R+AD++ D F +V CL+ L I Sbjct: 200 NSNGTLSRKEFREHFVRLGFDKKSV--QDALFRYADEDESDDVGFSEYVHLGLCLLVLRI 257 Query: 672 LF 673 L+ Sbjct: 258 LY 259 Score = 30.0 bits (66), Expect = 3.4, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 28/50 (56%) Query: 585 DEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA 634 DED S +G E+ L + + +Y D D+SG ++ E++K LE+A Sbjct: 233 DEDESDDVGFSEYVHLGLCLLVLRILYAFADFDKSGQLSKEEVQKVLEDA 282 >4OY4-A nrPDB Length = 415 Score = 33.1 bits (74), Expect = 0.39, Method: Compositional matrix adjust. Identities = 27/131 (20%), Positives = 60/131 (45%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D DG G + EF + + Sbjct: 32 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGDGTIDFPEFLTMMARK 83 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELI 656 K ++ +R D D +G +++ E+R + G KL ++ ++I D + Sbjct: 84 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 143 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 144 VNYEEFVQMMT 154 >1DTL-A nrPDB Length = 161 Score = 33.1 bits (74), Expect = 0.43, Method: Compositional matrix adjust. Identities = 32/141 (22%), Positives = 64/141 (45%), Gaps = 19/141 (13%) Query: 541 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 L ED IS EL ++R +L + + E + M+D +DEDGSG + EF ++ Sbjct: 29 LGAEDGSISTKELGKVMR-MLGQNP-------TPEELQEMIDEVDEDGSGTVDFDEFLVM 80 Query: 601 WTKIQK----------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVAR 649 + K ++R D + G ++ E++ L+ G + + +++ Sbjct: 81 MVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDG 140 Query: 650 FADDELIIDFDNFVRCLVRLE 670 +++ ID+D F+ + +E Sbjct: 141 DKNNDGRIDYDEFLEFMKGVE 161 >6HCS-A nrPDB Length = 167 Score = 33.1 bits (74), Expect = 0.45, Method: Compositional matrix adjust. Identities = 31/144 (21%), Positives = 67/144 (46%), Gaps = 22/144 (15%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D DG+G + EF + + Sbjct: 25 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 76 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELI 656 K ++ +R D D +G +++ E+R + G KL ++ ++I D + Sbjct: 77 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKLTDEEVDEMIREADIDGDGQ 136 Query: 657 IDFDNFVRCLVR------LEILFK 674 ++++ FV+ + LE+LF+ Sbjct: 137 VNYEEFVQMMTAKLEGTGLEVLFQ 160 >2N6A-A nrPDB Length = 173 Score = 32.3 bits (72), Expect = 0.64, Method: Compositional matrix adjust. Identities = 27/131 (20%), Positives = 61/131 (46%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D DG+G + EF + + Sbjct: 26 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 77 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELI 656 K ++ +R D D +G +++ E+R + G KL ++ ++I D + Sbjct: 78 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 137 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 138 VNYEEFVQMMT 148 >6O20-F nrPDB Length = 169 Score = 32.3 bits (72), Expect = 0.78, Method: Compositional matrix adjust. Identities = 27/131 (20%), Positives = 61/131 (46%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D DG+G + EF + + Sbjct: 45 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 96 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELI 656 K ++ +R D D +G +++ E+R + G KL ++ ++I D + Sbjct: 97 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 156 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 157 VNYEEFVQMMT 167 >3KF9-A nrPDB Length = 149 Score = 32.3 bits (72), Expect = 0.78, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 47/92 (51%), Gaps = 10/92 (10%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-LPCQLHQVIVARFADDELIIDFDNFV 663 Q+ ++ + D D SGT+++ E++ A+ GF+ ++ ++I D IDF+ F+ Sbjct: 8 QEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTIDFEEFL 67 Query: 664 RCLV--------RLEILFKIFKQLDPENTGTI 687 + + R EI+ K F+ D + TG I Sbjct: 68 QMMTAKMGERDSREEIM-KAFRLFDDDETGKI 98 Score = 28.9 bits (63), Expect = 7.3, Method: Compositional matrix adjust. Identities = 19/80 (23%), Positives = 39/80 (48%), Gaps = 7/80 (8%) Query: 575 ETCKIMVDMLDEDGSGKLGLKEFYILWT-------KIQKYQKIYREIDVDRSGTMNSYEM 627 E K M+ +D+DGSG + +EF + T ++ K +R D D +G ++ + Sbjct: 44 EEIKKMIADIDKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNL 103 Query: 628 RKALEEAGFKLPCQLHQVIV 647 ++ +E G + + Q ++ Sbjct: 104 KRVAKELGENMTDEELQEMI 123 >3WFN-B nrPDB Length = 182 Score = 32.3 bits (72), Expect = 0.82, Method: Compositional matrix adjust. Identities = 27/131 (20%), Positives = 61/131 (46%), Gaps = 16/131 (12%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI 604 D I+ EL T++R + + + + M++ +D DG+G + EF + + Sbjct: 31 DGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGTIDFPEFLTMMARK 82 Query: 605 QK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELI 656 K ++ +R D D +G +++ E+R + G KL ++ ++I D + Sbjct: 83 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 142 Query: 657 IDFDNFVRCLV 667 ++++ FV+ + Sbjct: 143 VNYEEFVQMMT 153 >4IL1-A nrPDB Length = 823 Score = 32.0 bits (71), Expect = 0.92, Method: Compositional matrix adjust. Identities = 40/204 (19%), Positives = 88/204 (43%), Gaps = 46/204 (22%) Query: 524 EANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 + EE I + F+ F+ + D I+ EL T++R + + + + M++ Sbjct: 4 QLTEEQIAE-FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAE--------LQDMIN 54 Query: 583 MLDEDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAG 635 +D DG+G + EF + + K ++ +R D D +G +++ E+R + G Sbjct: 55 EVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 114 Query: 636 FKLPC-QLHQVIVARFADDELIIDFDNFVRCLV--------------------------- 667 KL ++ ++I D + ++++ FV+ + Sbjct: 115 EKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDA 174 Query: 668 -RLEILFKIFKQLDPENTGTIQLD 690 ++ L K FK+LD +N+G++ ++ Sbjct: 175 DEIKRLGKRFKKLDLDNSGSLSVE 198 Score = 31.6 bits (70), Expect = 1.4, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 15/90 (16%) Query: 580 MVDMLDEDGSGKLGLKEFY-------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALE 632 ++D+ D DG+G++ KEF + K QK + +R D+D+ G +++ E+ + L+ Sbjct: 215 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 274 Query: 633 -EAGFKLP-CQLHQVIVARFADDELIIDFD 660 G L QL Q++ D+ II+ D Sbjct: 275 MMVGNNLKDTQLQQIV------DKTIINAD 298 >3O4Y-A nrPDB Length = 196 Score = 32.0 bits (71), Expect = 0.93, Method: Compositional matrix adjust. Identities = 21/89 (23%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFV 663 +QK + + +D + G + ++RK LE +G LP ++ +D ID+ F+ Sbjct: 54 VQKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNFDLLLDQIDSDGSGNIDYTEFL 113 Query: 664 -----RCLVRLEILFKIFKQLDPENTGTI 687 R + ++++ F+ D +N G I Sbjct: 114 AAAIDRRQLSKKLIYCAFRVFDVDNDGEI 142 >1ZFS-A nrPDB Length = 93 Score = 32.0 bits (71), Expect = 1.00, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 37/58 (63%), Gaps = 3/58 (5%) Query: 543 GEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 G+ ++S EL+ +L+ L+ D++ D +++ KIM + LDE+G G++ +EF +L Sbjct: 23 GDKYKLSKKELKDLLQTELSSFLDVQKDADAVD--KIMKE-LDENGDGEVDFQEFVVL 77 >5I0I-E nrPDB Length = 145 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 31/144 (21%), Positives = 69/144 (47%), Gaps = 19/144 (13%) Query: 534 FRRLFAQLAGEDAE--ISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGK 591 F+ F+ LA +D + I+ EL T++R + + + + M++ +D DG+G Sbjct: 11 FKEAFS-LADKDGDGTITTKELGTVMRSLGQNPTEAE--------LQDMINEVDADGNGT 61 Query: 592 LGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLH 643 + EF + + K ++ +R D D +G +++ E+R + G KL ++ Sbjct: 62 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 121 Query: 644 QVIVARFADDELIIDFDNFVRCLV 667 ++I D + ++++ FV+ + Sbjct: 122 EMIREADIDGDGQVNYEEFVQMMT 145 >2L1W-A nrPDB Length = 149 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 24/103 (23%), Positives = 52/103 (50%), Gaps = 8/103 (7%) Query: 575 ETCKIMVDMLDEDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEM 627 E + M+ +D DG+G + EF L K K ++ ++ D D++G +++ E+ Sbjct: 46 EELQDMISEVDADGNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASEL 105 Query: 628 RKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNFVRCLVRL 669 R + G KL ++ Q+I D + ++++ FV+ ++ + Sbjct: 106 RHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTV 148 >3SIA-A nrPDB Length = 220 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 33/65 (50%) Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631 S +T M+ + D D +G + EF ++ ++ ++ RSGT+ +E+ AL Sbjct: 84 LSPQTALRMMRIFDTDFNGHISFYEFMAMYKFMELAYNLFVMNARARSGTLEPHEILPAL 143 Query: 632 EEAGF 636 ++ GF Sbjct: 144 QQLGF 148 >4ORC-B nrPDB Length = 170 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 15/90 (16%) Query: 580 MVDMLDEDGSGKLGLKEFY-------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALE 632 ++D+ D DG+G++ KEF + K QK + +R D+D+ G +++ E+ + L+ Sbjct: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 117 Query: 633 -EAGFKLP-CQLHQVIVARFADDELIIDFD 660 G L QL Q++ D+ II+ D Sbjct: 118 MMVGNNLKDTQLQQIV------DKTIINAD 141 >5EQX-A nrPDB Length = 555 Score = 31.6 bits (70), Expect = 1.3, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 104 DCWLLAAIASLTLNEEILA-RVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKD 162 D A I L+ E+L +V LD+ + +N+ ++ F G W E+ D R T + Sbjct: 220 DSQYSARIEENILSSELLRFQVTDLDEEYTDNWLAVYFFTSGNEGNWFEIQTDPR--TNE 277 Query: 163 GELLFVHSAEGSEFWSALLEKA 184 G L V + + + S L A Sbjct: 278 GILKVVKALDYEQLQSVKLSIA 299 >2AAO-A nrPDB Length = 166 Score = 31.6 bits (70), Expect = 1.4, Method: Compositional matrix adjust. Identities = 23/95 (24%), Positives = 44/95 (46%), Gaps = 7/95 (7%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDN 661 +I ++++ ID D+SG + E++ L+ G L ++ ++ A D+ ID+ Sbjct: 25 EIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTIDYKE 84 Query: 662 FVRCLVRL------EILFKIFKQLDPENTGTIQLD 690 F+ + L + LF F D + +G I D Sbjct: 85 FIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPD 119 >4GJF-A nrPDB Length = 89 Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust. Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Query: 512 VDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDG 571 +DD +A +E++ +++ +F Q A ED IS EL ++R + Sbjct: 1 MDDIYKAAVEQLTEEQKNEFKAAFDIFVQGA-EDGCISTKELGKVMRML--------GQN 51 Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQK 606 + E + M+D +DEDGSG + EF ++ + K Sbjct: 52 PTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMK 86 >3NCG-A nrPDB Length = 486 Score = 31.2 bits (69), Expect = 1.7, Method: Compositional matrix adjust. Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 16/111 (14%) Query: 528 EDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDED 587 ED D L E S F I R +L RE ++ M D+D Sbjct: 380 EDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMER----------AFKMFDKD 429 Query: 588 GSGKLGLKEFYILWT------KIQKYQKIYREIDVDRSGTMNSYEMRKALE 632 GSGK+ KE + L++ ++++ + I ++D ++ G ++ E + L+ Sbjct: 430 GSGKISTKELFKLFSQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQ 480 >4E53-A nrPDB Length = 185 Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust. Identities = 21/95 (22%), Positives = 48/95 (50%), Gaps = 8/95 (8%) Query: 580 MVDMLDEDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALE 632 M++ +D DG+G + EF + + K ++ +R D D +G +++ E+R + Sbjct: 59 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 118 Query: 633 EAGFKLPC-QLHQVIVARFADDELIIDFDNFVRCL 666 G KL ++ ++I D + ++++ FV+ + Sbjct: 119 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 >2F2P-A nrPDB Length = 179 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 21/96 (21%), Positives = 48/96 (50%), Gaps = 8/96 (8%) Query: 580 MVDMLDEDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALE 632 M++ +D DG+G + EF + + K ++ +R D D +G +++ E+R + Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 111 Query: 633 EAGFKLPC-QLHQVIVARFADDELIIDFDNFVRCLV 667 G KL ++ ++I D + ++++ FV+ + Sbjct: 112 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147 >5UGH-A nrPDB Length = 397 Score = 30.4 bits (67), Expect = 2.8, Method: Compositional matrix adjust. Identities = 33/150 (22%), Positives = 66/150 (44%), Gaps = 32/150 (21%) Query: 541 LAGEDAEISAFELQTILRRVLAK-REDIKSDGFSIETCKIMV---------------DML 584 LAGE +A + Q ++R + D S GF +TC ++V D Sbjct: 69 LAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRN 128 Query: 585 DED-GSGKLGLKEFY--------ILWTKIQKYQKIYREIDVDRSGTM-------NSYEMR 628 +ED G+G GL Y + T + ++ + ++ R+GT+ + Sbjct: 129 EEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTV 188 Query: 629 KALEEAGFKLPCQLHQVIVARFADDELIID 658 + +++ G LP ++H ++++ D+E+ +D Sbjct: 189 QYMQDRGAVLPIRVHTIVISVQHDEEVCLD 218 >3AQL-A nrPDB Length = 415 Score = 29.6 bits (65), Expect = 4.4, Method: Compositional matrix adjust. Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 12/110 (10%) Query: 418 RQRKMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRA--RERSDTFINLREVLNRF 475 R K G + +G G+ ++ L G+ K+F +TT A + F N R V RF Sbjct: 27 RLNKAGYEAWLVGGGVRDL---LLGKK----PKDFDVTTNATPEQVRKLFRNCRLVGRRF 79 Query: 476 KLPP---GEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEE 522 +L G ++ +TF H G+ R S++ + + D I +IEE Sbjct: 80 RLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGSIEE 129 >2BL0-C nrPDB Length = 142 Score = 29.6 bits (65), Expect = 4.8, Method: Compositional matrix adjust. Identities = 20/93 (21%), Positives = 44/93 (47%), Gaps = 8/93 (8%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL-PCQLHQVIVARFADDELIIDFDN 661 ++ ++++ + D +R+G + ++ L++ G ++ P +++ A I F Sbjct: 4 QVSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQFPE 63 Query: 662 FVRCLVRL-------EILFKIFKQLDPENTGTI 687 F+ + R +IL + F+ DPE TG I Sbjct: 64 FLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYI 96 >5LNB-B nrPDB Length = 310 Score = 29.3 bits (64), Expect = 5.5, Method: Compositional matrix adjust. Identities = 13/57 (22%), Positives = 28/57 (49%) Query: 436 VPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPGEYVLVPSTFEPH 492 + + + + +HL +FF T +D + N+++ +N L +YV++P H Sbjct: 66 IEKSIIKREQVHLMSSFFYTKLISNPADYYSNVKKWVNNTDLFSKKYVVIPINISYH 122 >2TN4-A nrPDB Length = 159 Score = 28.9 bits (63), Expect = 7.7, Method: Compositional matrix adjust. Identities = 27/132 (20%), Positives = 63/132 (47%), Gaps = 19/132 (14%) Query: 546 AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQ 605 +IS EL T++R +L + + E +++ +DEDGSG + +EF ++ + Sbjct: 32 GDISVKELGTVMR-MLGQTP-------TKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQM 83 Query: 606 K----------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDE 654 K +++R D + G +++ E+ + +G + ++ ++ +++ Sbjct: 84 KEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRASGEHVTDEEIESLMKDGDKNND 143 Query: 655 LIIDFDNFVRCL 666 IDFD F++ + Sbjct: 144 GRIDFDEFLKMM 155 >1ZMZ-A nrPDB Length = 98 Score = 28.9 bits (63), Expect = 7.8, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 6/48 (12%) Query: 582 DMLDEDGSGKLGLKEFYILW------TKIQKYQKIYREIDVDRSGTMN 623 D+ D DG+G + +KE + K ++ +K+ EID + +G MN Sbjct: 38 DLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMN 85 >2JNF-A nrPDB Length = 158 Score = 28.9 bits (63), Expect = 8.2, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 4/58 (6%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWT 602 D E + + ++R +LA+ ++ S E M+D +D DGSG + +EF + T Sbjct: 101 DKEGNGYISTDVMREILAELDET----LSSEDLDAMIDEIDADGSGTVDFEEFMGVMT 154 >5NIL-D nrPDB Length = 371 Score = 28.9 bits (63), Expect = 8.9, Method: Compositional matrix adjust. Identities = 14/56 (25%), Positives = 32/56 (57%), Gaps = 2/56 (3%) Query: 502 FSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTIL 557 + K+A T+D +I+ N ++ + ++ + R+ A +AGE +I+ + QT++ Sbjct: 153 MAVKQAQIGTIDAQIKRNQASLDTAKTNLD--YTRIVAPMAGEVTQITTLQGQTVI 206 >5A9Q-8 nrPDB Length = 656 Score = 28.9 bits (63), Expect = 8.9, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 4/43 (9%) Query: 420 RKMGEDMHTIGFGIYEVPEELTGQTN----IHLSKNFFLTTRA 458 RK+ + H I G+ + EELTG++ + +SKN+ RA Sbjct: 69 RKLFNESHGIFLGLQRIDEELTGKSRKSQLVRVSKNYRSVIRA 111 >2K2A-A nrPDB Length = 70 Score = 28.5 bits (62), Expect = 9.3, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 4/47 (8%) Query: 556 ILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWT 602 ++R +LA+ ++ S E M+D +D DGSG + +EF + T Sbjct: 24 VMREILAELDET----LSSEDLDAMIDEIDADGSGTVDFEEFMGVMT 66 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3DF0-A nrPDB 1323 0.0 1KFU-L nrPDB 1281 0.0 1QXP-A nrPDB 1212 0.0 1MDW-A nrPDB 650 0.0 2NQG-A nrPDB 633 0.0 1ZCM-A nrPDB 611 e-175 2NQA-A nrPDB 607 e-174 2P0R-A nrPDB 551 e-157 6BDT-A nrPDB 515 e-146 1KFX-S nrPDB 277 1e-74 3BOW-B nrPDB 276 2e-74 4OKH-A nrPDB 256 3e-68 1NP8-A nrPDB 248 5e-66 1F4Q-A nrPDB 205 5e-53 1JUO-A nrPDB 204 1e-52 5MRA-A nrPDB 204 1e-52 1GJY-A nrPDB 201 7e-52 2I7A-A nrPDB 180 2e-45 3AAJ-A nrPDB 164 9e-41 1Y1X-A nrPDB 158 1e-38 3QRX-A nrPDB 97 2e-20 Sequences not found previously or not previously below threshold: 4IL1-A nrPDB 81 2e-15 3EK4-A nrPDB 78 1e-14 3KF9-A nrPDB 77 3e-14 1GGZ-A nrPDB 76 6e-14 3U0K-A nrPDB 75 1e-13 4OY4-A nrPDB 74 2e-13 2L1W-A nrPDB 74 2e-13 5UKG-A nrPDB 73 3e-13 2GGM-A nrPDB 73 4e-13 3WFN-B nrPDB 73 5e-13 2F2P-A nrPDB 73 5e-13 1CLM-A nrPDB 73 5e-13 6O20-F nrPDB 72 6e-13 4I2Y-A nrPDB 72 8e-13 2N6A-A nrPDB 72 8e-13 4E53-A nrPDB 72 9e-13 2OBH-A nrPDB 72 1e-12 1DTL-A nrPDB 72 1e-12 5I0I-E nrPDB 71 1e-12 5A2H-A nrPDB 70 3e-12 6HCS-A nrPDB 70 3e-12 5D43-A nrPDB 69 8e-12 2TN4-A nrPDB 68 2e-11 1TOP-A nrPDB 66 6e-11 3NCG-A nrPDB 64 3e-10 5E37-A nrPDB 64 3e-10 1OQP-A nrPDB 63 5e-10 2LMV-A nrPDB 62 8e-10 4DS7-A nrPDB 61 2e-09 2LC5-A nrPDB 61 2e-09 2LHI-A nrPDB 60 2e-09 1LKJ-A nrPDB 60 4e-09 3SIA-A nrPDB 58 9e-09 3HZT-A nrPDB 58 9e-09 1S6I-A nrPDB 58 1e-08 2AAO-A nrPDB 57 3e-08 4RGJ-A nrPDB 56 4e-08 3KHE-A nrPDB 56 5e-08 2LAP-A nrPDB 56 6e-08 4MVF-A nrPDB 55 8e-08 3PM8-A nrPDB 55 8e-08 3FWC-A nrPDB 55 9e-08 5B8I-B nrPDB 55 1e-07 1IJ5-A nrPDB 55 1e-07 3Q5I-A nrPDB 55 2e-07 4YZB-A nrPDB 54 2e-07 4JWQ-A nrPDB 54 2e-07 5JN2-A nrPDB 54 2e-07 4ZCV-A nrPDB 54 3e-07 4ORC-B nrPDB 53 4e-07 4N5X-A nrPDB 53 4e-07 2AMI-A nrPDB 53 4e-07 2BL0-C nrPDB 53 4e-07 2HF5-A nrPDB 53 5e-07 5ZOR-A nrPDB 52 7e-07 5H7D-E nrPDB 52 8e-07 1SR6-C nrPDB 52 9e-07 2LV7-A nrPDB 52 1e-06 3O4Y-A nrPDB 52 1e-06 5OTJ-D nrPDB 52 1e-06 2JNF-A nrPDB 51 1e-06 2LVK-A nrPDB 51 2e-06 2LHH-A nrPDB 50 2e-06 2I08-A nrPDB 50 2e-06 5COC-A nrPDB 50 4e-06 2M29-A nrPDB 50 5e-06 2N7L-C nrPDB 49 8e-06 1M39-A nrPDB 48 1e-05 5VLN-A nrPDB 48 1e-05 4Q57-A nrPDB 48 1e-05 2JOJ-A nrPDB 48 1e-05 2OPO-A nrPDB 48 1e-05 4WPX-A nrPDB 48 1e-05 3IFK-A nrPDB 48 1e-05 2ROB-A nrPDB 48 2e-05 3K21-A nrPDB 48 2e-05 2RO8-A nrPDB 47 2e-05 2KN2-A nrPDB 47 2e-05 3E3R-A nrPDB 47 2e-05 5JOJ-A nrPDB 47 2e-05 5Z1Q-A nrPDB 47 3e-05 4GJF-A nrPDB 47 3e-05 1FW4-A nrPDB 47 3e-05 2RO9-A nrPDB 47 4e-05 2B1U-A nrPDB 47 4e-05 2M5E-A nrPDB 46 4e-05 3LIJ-A nrPDB 46 5e-05 2K2I-A nrPDB 46 6e-05 1W7I-B nrPDB 46 7e-05 1GGW-A nrPDB 46 7e-05 3JAX-C nrPDB 45 8e-05 2JNX-A nrPDB 45 1e-04 5JOL-A nrPDB 45 1e-04 1QX2-A nrPDB 45 1e-04 3I5I-C nrPDB 45 1e-04 5H53-C nrPDB 45 1e-04 1ZMZ-A nrPDB 44 2e-04 6MI5-X nrPDB 44 2e-04 2GGZ-A nrPDB 44 2e-04 3L19-A nrPDB 44 2e-04 2G9B-A nrPDB 44 2e-04 2K7C-A nrPDB 44 2e-04 2KZ2-A nrPDB 44 2e-04 2KSZ-A nrPDB 44 2e-04 1JFJ-A nrPDB 44 2e-04 2K7B-A nrPDB 44 3e-04 5H53-B nrPDB 43 4e-04 2ZFD-A nrPDB 43 4e-04 5MWC-D nrPDB 43 5e-04 1H4B-A nrPDB 43 5e-04 3MSE-B nrPDB 42 6e-04 1S6J-A nrPDB 42 6e-04 4D1E-A nrPDB 42 7e-04 2BL0-B nrPDB 42 8e-04 1UHN-A nrPDB 42 9e-04 2QFE-A nrPDB 42 0.001 3JBH-C nrPDB 42 0.001 1O1A-B nrPDB 42 0.001 1I84-U nrPDB 41 0.002 5TBY-C nrPDB 41 0.002 6FSA-D nrPDB 41 0.002 2W4G-C nrPDB 41 0.002 5T7C-A nrPDB 41 0.002 1TRF-A nrPDB 41 0.002 1TNP-A nrPDB 41 0.002 5M6C-E nrPDB 40 0.003 2Q4U-A nrPDB 40 0.003 1JC2-A nrPDB 40 0.004 2JUL-A nrPDB 40 0.004 1F55-A nrPDB 40 0.005 5TBY-E nrPDB 40 0.005 2E30-A nrPDB 40 0.005 2BEC-A nrPDB 39 0.005 1BJF-A nrPDB 38 0.010 3TZ1-A nrPDB 38 0.010 5I2L-A nrPDB 38 0.010 1SJJ-A nrPDB 38 0.011 2PMY-A nrPDB 38 0.012 2M8U-A nrPDB 38 0.013 2M97-A nrPDB 38 0.013 1OZS-A nrPDB 38 0.015 2LVV-A nrPDB 38 0.016 2N8Y-A nrPDB 38 0.017 1ZFS-A nrPDB 38 0.018 2LCP-A nrPDB 38 0.020 1QLS-A nrPDB 37 0.024 2I94-A nrPDB 37 0.030 3DTP-E nrPDB 37 0.038 1S36-A nrPDB 36 0.054 2K2A-A nrPDB 36 0.055 1N2D-A nrPDB 36 0.055 2OS8-B nrPDB 36 0.055 2L2E-A nrPDB 36 0.055 1JF0-A nrPDB 36 0.061 6EPA-A nrPDB 36 0.063 1NSH-A nrPDB 35 0.085 5PAL-A nrPDB 35 0.092 3PAT-A nrPDB 35 0.094 3I5H-B nrPDB 35 0.10 2LUC-A nrPDB 35 0.10 2JU0-A nrPDB 35 0.11 1NYA-A nrPDB 35 0.11 3KPX-A nrPDB 35 0.11 5ZGM-A nrPDB 35 0.14 5W1A-B nrPDB 35 0.15 1RTP-1 nrPDB 35 0.15 3TS5-B nrPDB 35 0.15 3J04-B nrPDB 35 0.16 1G33-A nrPDB 34 0.20 2EC6-B nrPDB 34 0.23 2L0P-A nrPDB 34 0.25 2FCE-A nrPDB 34 0.25 2QJ0-A nrPDB 34 0.26 1DFK-Y nrPDB 34 0.28 1B7T-Y nrPDB 34 0.28 3GMC-A nrPDB 34 0.29 2KQY-A nrPDB 33 0.34 1CB1-A nrPDB 33 0.39 1JBA-A nrPDB 33 0.40 5XOP-A nrPDB 33 0.42 2D8N-A nrPDB 33 0.45 2AUC-A nrPDB 33 0.46 3DD4-A nrPDB 33 0.55 1C7W-A nrPDB 33 0.56 1RK9-A nrPDB 33 0.62 5LNB-B nrPDB 32 0.68 3AQL-A nrPDB 32 0.84 1TIZ-A nrPDB 32 0.87 1DGU-A nrPDB 32 0.99 2LM5-A nrPDB 32 0.99 1SL8-A nrPDB 32 0.99 1UHK-A nrPDB 32 1.0 2NLN-A nrPDB 32 1.3 1TTX-A nrPDB 32 1.3 2M7L-A nrPDB 31 1.6 3AKA-A nrPDB 31 1.7 4RI0-A nrPDB 31 1.8 5B7X-A nrPDB 31 1.9 2KYF-A nrPDB 31 2.0 5ZH6-A nrPDB 31 2.2 5XND-A nrPDB 31 2.3 5VE9-A nrPDB 31 2.4 3CS1-A nrPDB 31 2.4 2M7M-A nrPDB 30 2.5 5LCW-N nrPDB 30 2.6 2Y5I-A nrPDB 30 2.7 2MA2-A nrPDB 30 2.9 1KQV-A nrPDB 30 2.9 2I18-A nrPDB 30 3.0 6AGH-A nrPDB 30 3.1 4NSC-A nrPDB 30 3.7 4NQG-A nrPDB 30 3.8 6EAZ-A nrPDB 30 4.0 2NA0-A nrPDB 30 4.0 6AGI-A nrPDB 30 4.4 4PCW-A nrPDB 30 5.1 2NCO-A nrPDB 30 5.2 6ED3-A nrPDB 30 5.3 5CPV-A nrPDB 29 5.9 4OCI-A nrPDB 29 6.3 4PAL-A nrPDB 29 8.4 6IIE-A nrPDB 28 9.7 >3DF0-A nrPDB Length = 714 Score = 1323 bits (3423), Expect = 0.0, Method: Composition-based stats. Identities = 699/700 (99%), Positives = 699/700 (99%) Query: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGF 60 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGF Sbjct: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGF 60 Query: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI 120 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGD WLLAAIASLTLNEEI Sbjct: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDSWLLAAIASLTLNEEI 120 Query: 121 LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL Sbjct: 121 LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 Query: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC 240 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC Sbjct: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC 240 Query: 241 SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN 300 SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN Sbjct: 241 SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN 300 Query: 301 CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK 360 CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK Sbjct: 301 CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK 360 Query: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQR 420 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQR Sbjct: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQR 420 Query: 421 KMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPG 480 KMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPG Sbjct: 421 KMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPG 480 Query: 481 EYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQ 540 EYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQ Sbjct: 481 EYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQ 540 Query: 541 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL Sbjct: 541 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 Query: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFD 660 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFD Sbjct: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFD 660 Query: 661 NFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 700 NFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL Sbjct: 661 NFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 700 >1KFU-L nrPDB Length = 699 Score = 1281 bits (3316), Expect = 0.0, Method: Composition-based stats. Identities = 653/699 (93%), Positives = 679/699 (97%) Query: 2 AGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFK 61 AGIA KLAKDREAAEGLGSHERAIKYLNQDYE LRNECLEAG LFQDPSFPA+PS+LGFK Sbjct: 1 AGIAAKLAKDREAAEGLGSHERAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFK 60 Query: 62 ELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL 121 ELGPYSSKTRG+ WKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL Sbjct: 61 ELGPYSSKTRGMRWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEIL 120 Query: 122 ARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL 181 ARVVPL+QSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL Sbjct: 121 ARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALL 180 Query: 182 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCS 241 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYEL+KPPPNLFKIIQKAL+KGSLLGCS Sbjct: 181 EKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS 240 Query: 242 IDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNC 301 IDITSAADSEA+T+QKLVKGHAYSVTGAEEVES+GSLQKLIRIRNPWG+VEWTG+WNDNC Sbjct: 241 IDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNC 300 Query: 302 PSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTKM 361 PSWNT+DPE R LT R EDGEFWMSFSDFLRHYSRLEICNLTPDTLT D+YKKWKLTKM Sbjct: 301 PSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKM 360 Query: 362 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQRK 421 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDED+EDGE GCTFLVGLIQKHRRRQRK Sbjct: 361 DGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRK 420 Query: 422 MGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPGE 481 MGEDMHTIGFGIYEVPEEL+GQTNIHLSKNFFLT RARERSDTFINLREVLNRFKLPPGE Sbjct: 421 MGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGE 480 Query: 482 YVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQL 541 Y+LVPSTFEP+K+GDFCIRVFSEKKADYQ VDDEIEAN+EE + +E+DI DG RRLFAQL Sbjct: 481 YILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGVRRLFAQL 540 Query: 542 AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILW 601 AGEDAEISAFELQTILRRVLAKR+DIKSDGFSIETCKIMVDMLD DGSGKLGLKEFYILW Sbjct: 541 AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILW 600 Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDN 661 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK+PCQLHQVIVARFADD+LIIDFDN Sbjct: 601 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDN 660 Query: 662 FVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 700 FVRCLVRLE LFKIFKQLDPENTGTI+LDLISWL FSVL Sbjct: 661 FVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 699 >1QXP-A nrPDB Length = 900 Score = 1212 bits (3137), Expect = 0.0, Method: Composition-based stats. Identities = 489/703 (69%), Positives = 588/703 (83%), Gaps = 4/703 (0%) Query: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGF 60 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDP+FP + SLGF Sbjct: 1 MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPAFPPVSHSLGF 60 Query: 61 KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI 120 KELGP SSKT GI+WKRPTE+ ++PQFI+ GATRTDICQGALGD WLLAAIASLTLNE I Sbjct: 61 KELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDSWLLAAIASLTLNETI 120 Query: 121 LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL 180 L RVVP QSFQE YAGIFHFQ WQ+GEWV+VVVDD LPTKDG+L+FVHSA+G+EFWSAL Sbjct: 121 LHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSAL 180 Query: 181 LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC 240 LEKAYAK+NG YEALSGG T+E FEDFTGG+ EWY+L+K P +L++II KALE+GSLLGC Sbjct: 181 LEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGC 240 Query: 241 SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN 300 SI+I+ D EA+T++ LV+GHAYSVT A++V G LIR+RNPWG+VEW G W+DN Sbjct: 241 SINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDN 300 Query: 301 CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK 360 WN VDP R L + EDGEFWMSF DF+R +++LEICNLTPD L + + W T Sbjct: 301 SYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDALKSRTLRNWNTTF 360 Query: 361 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEE-EDEDDEDG-ERGCTFLVGLIQKHRRR 418 +G WRRGSTAGGCRNYP TFW+NPQ+ I+LEE +D DD D E GC+FL+ L+QKHRRR Sbjct: 361 YEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEEVDDADDYDSRESGCSFLLALMQKHRRR 420 Query: 419 QRKMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLP 478 +R+ G DM TIGF +Y+VP EL GQ +HL ++FFL +R +S+ FINLREV NR +LP Sbjct: 421 ERRFGRDMETIGFAVYQVPRELAGQP-VHLKRDFFLANASRAQSEHFINLREVSNRIRLP 479 Query: 479 PGEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANI-EEIEANEEDIGDGFRRL 537 PGEY++VPSTFEP+K GDF +R FSEKKA Q +DD+I+AN+ +E +EE+I D F+ L Sbjct: 480 PGEYIVVPSTFEPNKEGDFLLRFFSEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTL 539 Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 F++LAG+D EIS ELQTIL R+++K +D++++GFS+E+C+ MV+++D DG+GKLGL EF Sbjct: 540 FSKLAGDDMEISVKELQTILNRIISKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEF 599 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELII 657 ILW +I+ Y I+R+ D+D+SG+M++YEMR A+E AGFKLPCQLHQVIVARFADDELII Sbjct: 600 NILWNRIRNYLTIFRKFDLDKSGSMSAYEMRMAIEAAGFKLPCQLHQVIVARFADDELII 659 Query: 658 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 700 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL Sbjct: 660 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL 702 Score = 274 bits (702), Expect = 7e-74, Method: Composition-based stats. Identities = 83/177 (46%), Positives = 122/177 (68%) Query: 523 IEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 IEANE + FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 722 IEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 781 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 ++D D +GKLG +EF LW I+K+Q IY+ + DRSGT+ S E+ A E AGF L + Sbjct: 782 VMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFETDRSGTIGSNELPGAFEAAGFHLNQHI 841 Query: 643 HQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ F+ LD TG IQ+++ WL ++ Sbjct: 842 YSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEWLQLTM 898 >1MDW-A nrPDB Length = 328 Score = 650 bits (1678), Expect = 0.0, Method: Composition-based stats. Identities = 327/328 (99%), Positives = 327/328 (99%) Query: 19 GSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRP 78 GSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRP Sbjct: 1 GSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRP 60 Query: 79 TEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGI 138 TEICADPQFIIGGATRTDICQGALGD WLLAAIASLTLNEEILARVVPLDQSFQENYAGI Sbjct: 61 TEICADPQFIIGGATRTDICQGALGDSWLLAAIASLTLNEEILARVVPLDQSFQENYAGI 120 Query: 139 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG 198 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG Sbjct: 121 FHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGG 180 Query: 199 ATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKL 258 ATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKL Sbjct: 181 ATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKL 240 Query: 259 VKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTER 318 VKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTER Sbjct: 241 VKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTER 300 Query: 319 QEDGEFWMSFSDFLRHYSRLEICNLTPD 346 QEDGEFWMSFSDFLRHYSRLEICNLTPD Sbjct: 301 QEDGEFWMSFSDFLRHYSRLEICNLTPD 328 >2NQG-A nrPDB Length = 339 Score = 633 bits (1633), Expect = 0.0, Method: Composition-based stats. Identities = 233/330 (70%), Positives = 272/330 (82%) Query: 17 GLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWK 76 GLG HE AIKYL QDYE LR CL+ G LFQD +FP + SLGFKELGP SSKT GI+WK Sbjct: 2 GLGRHENAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWK 61 Query: 77 RPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYA 136 RPTE+ ++PQFI+ GATRTDICQGALGDCWLLAAIASLTLNE IL RVVP QSFQE YA Sbjct: 62 RPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYA 121 Query: 137 GIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALS 196 GIFHFQ WQ+GEWV+VVVDD LPTKDG+L+FVHSA+G+EFWSALLEKAYAK+NG YEALS Sbjct: 122 GIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALS 181 Query: 197 GGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQ 256 GG T+E FEDFTGG+ EWY+L+K P +L++II KALE+GSLLGCSI+I+ D EA+T++ Sbjct: 182 GGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFK 241 Query: 257 KLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLT 316 LV+GHAYSVT A++V G LIR+RNPWG+VEW G W+DN WN VDP R L Sbjct: 242 NLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLR 301 Query: 317 ERQEDGEFWMSFSDFLRHYSRLEICNLTPD 346 + EDGEFWMSF DF+R +++LEICNLTPD Sbjct: 302 VKMEDGEFWMSFRDFIREFTKLEICNLTPD 331 >1ZCM-A nrPDB Length = 321 Score = 611 bits (1576), Expect = e-175, Method: Composition-based stats. Identities = 228/321 (71%), Positives = 270/321 (84%) Query: 23 RAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEIC 82 AIKYL QDYE LR CL++G LF+D +FP +P SLG+K+LGP SSKT GI+WKRPTE+ Sbjct: 1 NAIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELL 60 Query: 83 ADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQ 142 ++PQFI+ GATRTDICQGALGDCWLLAAIASLTLN+ +L RVVP QSFQ YAGIFHFQ Sbjct: 61 SNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQ 120 Query: 143 FWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTE 202 WQ+GEWV+VVVDD LP KDG+L+FVHSAEG+EFWSALLEKAYAK+NG YEALSGG+T+E Sbjct: 121 LWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSE 180 Query: 203 GFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGH 262 FEDFTGG+ EWYELRK P +L++II KALE+GSLLGCSIDI+S D EA+T++KLVKGH Sbjct: 181 AFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGH 240 Query: 263 AYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQEDG 322 AYSVTGA++V G + LIR+RNPWG+VEWTG W+D+ WN VDP R L + EDG Sbjct: 241 AYSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDG 300 Query: 323 EFWMSFSDFLRHYSRLEICNL 343 EFWMSF DF+R ++RLEICNL Sbjct: 301 EFWMSFRDFMREFTRLEICNL 321 >2NQA-A nrPDB Length = 326 Score = 607 bits (1566), Expect = e-174, Method: Composition-based stats. Identities = 235/324 (72%), Positives = 283/324 (87%) Query: 23 RAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEIC 82 A+KYL QD++TLR +CL++G LF+DP FPA PS+LG+K+LGP S +T+GI WKRPTE+C Sbjct: 3 NALKYLGQDFKTLRQQCLDSGVLFKDPEFPACPSALGYKDLGPGSPQTQGIIWKRPTELC 62 Query: 83 ADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQ 142 PQFI+GGATRTDICQG LGDCWLLAAIASLTLNEE+L RVVP DQ FQENYAGIFHFQ Sbjct: 63 PSPQFIVGGATRTDICQGGLGDCWLLAAIASLTLNEELLYRVVPRDQDFQENYAGIFHFQ 122 Query: 143 FWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTE 202 FWQYGEWVEVV+DDRLPTK+G+LLF+HS +G+EFWSALLEKAYAK+NGCYEAL+GG+T E Sbjct: 123 FWQYGEWVEVVIDDRLPTKNGQLLFLHSEQGNEFWSALLEKAYAKLNGCYEALAGGSTVE 182 Query: 203 GFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGH 262 GFEDFTGGI+E+Y+L+KPP NL++II+KAL GSLLGCSID+ SAA++EA+T QKLVK H Sbjct: 183 GFEDFTGGISEFYDLKKPPANLYQIIRKALCAGSLLGCSIDVYSAAEAEAITSQKLVKSH 242 Query: 263 AYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQEDG 322 AYSVTG EEV G +KLIR+RNPWG+VEW+G W+D+ P WN +DP + L ++ EDG Sbjct: 243 AYSVTGVEEVNFQGHPEKLIRLRNPWGEVEWSGAWSDDAPEWNHIDPRRKEELDKKVEDG 302 Query: 323 EFWMSFSDFLRHYSRLEICNLTPD 346 EFWMS SDF+R +SRLEICNL+PD Sbjct: 303 EFWMSLSDFVRQFSRLEICNLSPD 326 >2P0R-A nrPDB Length = 333 Score = 551 bits (1420), Expect = e-157, Method: Composition-based stats. Identities = 191/326 (58%), Positives = 237/326 (72%), Gaps = 6/326 (1%) Query: 23 RAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEIC 82 R Q +E +R ECL+ G LF+D FPA SSL + E WKRP EI Sbjct: 13 RITHSSGQSFEQMRQECLQRGTLFEDADFPASNSSLFYSE-----RPQIPFVWKRPGEIV 67 Query: 83 ADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQ 142 +P+FI+GGATRTDICQG LGDCWLLAAIASLTLN++ LARV+P DQSF YAGIFHFQ Sbjct: 68 KNPEFILGGATRTDICQGELGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIFHFQ 127 Query: 143 FWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTE 202 FWQ+ EW++VV+DDRLPT L+F+HSA+ +EFWSALLEKAYAK+NG YEAL GG+ E Sbjct: 128 FWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIE 187 Query: 203 GFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGH 262 EDFTGG+AE ++ ++ P N ++I++KAL++GSLLGC ID SAA+SEA T L+KGH Sbjct: 188 AMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCFIDTRSAAESEARTPFGLIKGH 247 Query: 263 AYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQ-ED 321 AYSVTG ++V G +LIRIRNPWGQVEW G W+D+ P W +V P + L +D Sbjct: 248 AYSVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSDSSPEWRSVGPAEQKRLCHTALDD 307 Query: 322 GEFWMSFSDFLRHYSRLEICNLTPDT 347 GEFWM+F DF H+ ++EICNLTPD Sbjct: 308 GEFWMAFKDFKAHFDKVEICNLTPDA 333 >6BDT-A nrPDB Length = 382 Score = 515 bits (1327), Expect = e-146, Method: Composition-based stats. Identities = 186/366 (50%), Positives = 236/366 (64%), Gaps = 54/366 (14%) Query: 30 QDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEICADPQFII 89 + +E L +CLE L+ DP FP +SL + + P WKRP EIC +P+FII Sbjct: 14 KTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQ-----FVWKRPPEICENPRFII 68 Query: 90 GGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQFWQYGEW 149 GA RTDICQG LGD W LAAIA LTLN+ +L RV+P DQSF ENYAGIFHFQFW+YGEW Sbjct: 69 DGANRTDICQGELGDSWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEW 128 Query: 150 VEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTG 209 V+VV+DD LPT + +L+F S +EFWSALLEKAYAK++G YEAL GG TTE EDFTG Sbjct: 129 VDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTG 188 Query: 210 GIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDI-------TSAA-------------- 248 G+AE++E+R P +++KI++KA+E+GSL+GCSID TS + Sbjct: 189 GVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRN 248 Query: 249 -------DSE---------------AVTYQ-----KLVKGHAYSVTGAEEVESSGSLQKL 281 DS+ V Y+ LV+GHAYSVTG +EV G KL Sbjct: 249 MDNSLLQDSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFKGEKVKL 308 Query: 282 IRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTER-QEDGEFWMSFSDFLRHYSRLEI 340 +R+RNPWGQVEW G W+D W+ VD + +A L + EDGEFWMS+ DF+ H+++LEI Sbjct: 309 VRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEI 368 Query: 341 CNLTPD 346 CNLT D Sbjct: 369 CNLTAD 374 >1KFX-S nrPDB Length = 184 Score = 277 bits (709), Expect = 1e-74, Method: Composition-based stats. Identities = 87/177 (49%), Positives = 125/177 (70%) Query: 523 IEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 IEANE + FRRLFAQLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 6 IEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 65 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 ++D D +GKLG +EF LW I+++Q IY++ D DRSGT+ S E+ A E AGF L L Sbjct: 66 VMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHL 125 Query: 643 HQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ FK LD + TG IQ+++ WL ++ Sbjct: 126 YNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 182 >3BOW-B nrPDB Length = 184 Score = 276 bits (706), Expect = 2e-74, Method: Composition-based stats. Identities = 84/177 (47%), Positives = 122/177 (68%) Query: 523 IEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 IEANE + FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 6 IEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 65 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 ++D D +GKLG +EF LW I+K+Q IY+ D DRSGT+ S E+ A E AGF L + Sbjct: 66 VMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHI 125 Query: 643 HQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ F+ LD TG IQ+++ WL ++ Sbjct: 126 YSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEWLQLTM 182 >4OKH-A nrPDB Length = 189 Score = 256 bits (654), Expect = 3e-68, Method: Composition-based stats. Identities = 80/173 (46%), Positives = 122/173 (70%) Query: 527 EEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E + FR +F Q+AG+D EI A EL+ +L V+ K +D+K+ GF++E+C+ M+ ++D Sbjct: 7 ESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDT 66 Query: 587 DGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVI 646 DGSGKL L+EF+ LW KI+ +QKI++ D D+SGT+NSYEMR A+ +AGF L QL+ +I Sbjct: 67 DGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDII 126 Query: 647 VARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 R+AD + IDFD+F+ C VRLE +F+ F D + G I+L+++ WL ++ Sbjct: 127 TMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTM 179 >1NP8-A nrPDB Length = 159 Score = 248 bits (634), Expect = 5e-66, Method: Composition-based stats. Identities = 78/158 (49%), Positives = 111/158 (70%) Query: 523 IEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 IEANE + FR+LF QLAG+D E+SA EL IL +V+ + D+K+DGF I+TC+ MV Sbjct: 2 IEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVA 61 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 ++D D +GKLG +EF LW I+K+Q IY+ D DRSGT+ S E+ A E AGF L + Sbjct: 62 VMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHI 121 Query: 643 HQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLD 680 + +I+ R++D+ +DFDNF+ CLVRL+ +F+ F+ LD Sbjct: 122 YSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLD 159 >1F4Q-A nrPDB Length = 165 Score = 205 bits (522), Expect = 5e-53, Method: Composition-based stats. Identities = 54/162 (33%), Positives = 89/162 (54%), Gaps = 4/162 (2%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 F+ +AG+D E+ A ELQ L + + FS+ETC+IM+ MLD D +GK+G F Sbjct: 6 FSAVAGQDGEVDAEELQRCLTQ---SGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAF 62 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELII 657 LW + +++ + +D D SGT+ +E+R+A+ G++L Q IV R++ + I Sbjct: 63 KELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIF 122 Query: 658 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 FD++V C V+L L FK+ D G+ +L ++ Sbjct: 123 -FDDYVACCVKLRALTDFFKKRDHLQQGSADFIYDDFLQGTM 163 >1JUO-A nrPDB Length = 198 Score = 204 bits (519), Expect = 1e-52, Method: Composition-based stats. Identities = 54/162 (33%), Positives = 86/162 (53%), Gaps = 4/162 (2%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 FA +AG+D +I A ELQ L + F++ETC++MV MLD D SG +G EF Sbjct: 39 FAAVAGQDGQIDADELQRCLTQ---SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEF 95 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELII 657 LW + +++ + D DRSGT++ E++KAL GF+L Q I R++ + I Sbjct: 96 KELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTN-GKI 154 Query: 658 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 FD+++ C V+L L F++ D G + ++ + Sbjct: 155 TFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196 >5MRA-A nrPDB Length = 167 Score = 204 bits (518), Expect = 1e-52, Method: Composition-based stats. Identities = 54/162 (33%), Positives = 86/162 (53%), Gaps = 4/162 (2%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 FA +AG+D +I A ELQ L + F++ETC++MV MLD D SG +G EF Sbjct: 8 FAAVAGQDGQIDADELQRCLTQ---SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEF 64 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELII 657 LW + +++ + D DRSGT++ E++KAL GF+L Q I R++ + I Sbjct: 65 KELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTN-GKI 123 Query: 658 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 FD+++ C V+L L F++ D G + ++ + Sbjct: 124 TFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 165 >1GJY-A nrPDB Length = 167 Score = 201 bits (512), Expect = 7e-52, Method: Composition-based stats. Identities = 54/162 (33%), Positives = 85/162 (52%), Gaps = 4/162 (2%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 FA +AG+D +I A ELQ L + F++ETC++MV MLD D SG +G EF Sbjct: 8 FASVAGQDGQIDADELQRCLTQ---SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEF 64 Query: 598 YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELII 657 LW + +++ + D DRSGT++ E++KAL GF+L Q I R++ I Sbjct: 65 KELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYSTS-GKI 123 Query: 658 DFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 FD+++ C V+L L F++ D G + ++ + Sbjct: 124 TFDDYIACCVKLRALTDSFRRRDSAQQGMVNFSYDDFIQCVM 165 >2I7A-A nrPDB Length = 174 Score = 180 bits (457), Expect = 2e-45, Method: Composition-based stats. Identities = 42/163 (25%), Positives = 84/163 (51%), Gaps = 8/163 (4%) Query: 541 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 L ++I A +LQ +L + L D FS++ C+ +V +++ +G+L +EF L Sbjct: 14 LVPRGSDIDATQLQGLLNQELLTGP--PGDMFSLDECRSLVALMELKVNGRLDQEEFARL 71 Query: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA----GFKLPCQLHQVIVARFADDELI 656 W ++ YQ +++++ G + S ++ KA+E G + +L ++ R++D Sbjct: 72 WKRLVHYQHVFQKVQTS-PGVLLSSDLWKAIENTDFLRGIFISRELLHLVTLRYSDSVGR 130 Query: 657 IDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 + F + V L+RLE + K F+ L + G + L + W+S + Sbjct: 131 VSFPSLVCFLMRLEAMAKTFRNLSKDGKG-LYLTEMEWMSLVM 172 >3AAJ-A nrPDB Length = 167 Score = 164 bits (416), Expect = 9e-41, Method: Composition-based stats. Identities = 44/160 (27%), Positives = 79/160 (49%), Gaps = 12/160 (7%) Query: 544 EDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTK 603 IS ELQ L + F+ T + ++ M D + + EF +W Sbjct: 17 RSGVISDTELQQAL-------SNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKY 69 Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARF-ADDELIIDFDNF 662 I +Q ++R D D SG ++ E+++AL +G++L Q H +++ +F I FD+F Sbjct: 70 ITDWQNVFRTYDRDNSGMIDKNELKQAL--SGYRLSDQFHDILIRKFDRQGRGQIAFDDF 127 Query: 663 VRCLVRLEILFKIFKQLDPENTGTIQLDLISWLS--FSVL 700 ++ + L+ L IF++ D + G IQ+ +LS FS++ Sbjct: 128 IQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV 167 >1Y1X-A nrPDB Length = 191 Score = 158 bits (399), Expect = 1e-38, Method: Composition-based stats. Identities = 39/164 (23%), Positives = 74/164 (45%), Gaps = 10/164 (6%) Query: 538 FAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKE 596 F + + IS EL L FS+ T + ++ M D++ SG++ E Sbjct: 33 FRAVDTDGSGAISVPELNAALSS--------AGVPFSLATTEKLLHMYDKNHSGEITFDE 84 Query: 597 FYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADD-EL 655 F L I ++ +R+ D G ++S E+R AL +G+++ Q Q ++ +F Sbjct: 85 FKDLHHFILSMREGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQALMRKFDRQRRG 144 Query: 656 IIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 + FD++V + + + +F D E TG + +++ SV Sbjct: 145 SLGFDDYVELSIFVCRVRNVFAFYDRERTGQVTFTFDTFIGGSV 188 Score = 54.6 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 38/93 (40%), Gaps = 1/93 (1%) Query: 601 WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDE-LIIDF 659 Q+ + +R +D D SG ++ E+ AL AG + ++ + + I F Sbjct: 23 MNDNQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDKNHSGEITF 82 Query: 660 DNFVRCLVRLEILFKIFKQLDPENTGTIQLDLI 692 D F + + + F++ D G + + + Sbjct: 83 DEFKDLHHFILSMREGFRKRDSSGDGRLDSNEV 115 >3QRX-A nrPDB Length = 169 Score = 97.4 bits (241), Expect = 2e-20, Method: Composition-based stats. Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 21/150 (14%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSI--ETCKIMVDML 584 E+ R F + I A EL+ +R + GF E K M+ + Sbjct: 24 EEQKQEIREAFDLFDTDGSGTIDAKELKVAMRAL----------GFEPKKEEIKKMISEI 73 Query: 585 DEDGSGKLGLKEFYILWT-------KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D+DGSG + +EF + T ++ K +R D D SGT+ ++R+ +E G Sbjct: 74 DKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGEN 133 Query: 638 LP-CQLHQVIVARFADDELIIDFDNFVRCL 666 L +L ++I +D+ ID D F+R + Sbjct: 134 LTEEELQEMIAEADRNDDNEIDEDEFIRIM 163 Score = 60.8 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 30/120 (25%), Positives = 58/120 (48%), Gaps = 13/120 (10%) Query: 578 KIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 K +V + G++GL E + Q+ ++ + D D SGT+++ E++ A+ GF+ Sbjct: 6 KTVVSARRDQKKGRVGLTE-----EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFE 60 Query: 638 -LPCQLHQVIVARFADDELIIDFDNFVRCLV-------RLEILFKIFKQLDPENTGTIQL 689 ++ ++I D IDF+ F+ + E + K F+ D +N+GTI + Sbjct: 61 PKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITI 120 >4IL1-A nrPDB Length = 823 Score = 80.8 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 87/207 (42%), Gaps = 47/207 (22%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 7 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 58 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+G + EF + + ++ ++ +R D D +G +++ E+R + G KL Sbjct: 59 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLT 118 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCLV----------------------------RLE 670 ++ ++I D + ++++ FV+ + ++ Sbjct: 119 DEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIK 178 Query: 671 ILFKIFKQLDPENTGTIQLDLISWLSF 697 L K FK+LD +N+G+ L + ++S Sbjct: 179 RLGKRFKKLDLDNSGS--LSVEEFMSL 203 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 66/150 (44%), Gaps = 26/150 (17%) Query: 527 EEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 + D + F +L ++ +S E ++ +++ + + ++D+ D Sbjct: 173 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSL--------PELQQNPL----VQRVIDIFD 220 Query: 586 EDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEA-GFK 637 DG+G++ KEF ++ QK + +R D+D+ G +++ E+ + L+ G Sbjct: 221 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNN 280 Query: 638 LPC-QLHQV----IVARFADDELIIDFDNF 662 L QL Q+ I+ D + I F+ F Sbjct: 281 LKDTQLQQIVDKTIINADKDGDGRISFEEF 310 >3EK4-A nrPDB Length = 451 Score = 78.1 bits (191), Expect = 1e-14, Method: Composition-based stats. Identities = 37/186 (19%), Positives = 84/186 (45%), Gaps = 23/186 (12%) Query: 494 NGDFCIRVFSEKKADYQT----VDDEIEANIEEIEANEEDIGDGFRRLFAQLAGE-DAEI 548 GD + K D++ + ++E N + + EE I + F+ F+ + D I Sbjct: 273 EGDTLVNRIELKGIDFKEDGNILGHKLEYNTRD-QLTEEQIAE-FKEAFSLFDKDGDGTI 330 Query: 549 SAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI---- 604 + EL T++R + + + M++ +D DG+G + EF + + Sbjct: 331 TTKELGTVMRSL--------GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDT 382 Query: 605 ---QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFD 660 ++ ++ +R D D +G +++ E+R + G KL ++ ++I D + ++++ Sbjct: 383 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 442 Query: 661 NFVRCL 666 FV+ + Sbjct: 443 EFVQMM 448 Score = 66.6 bits (161), Expect = 3e-11, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 59/145 (40%), Gaps = 21/145 (14%) Query: 551 FELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKI 610 FE T++ R+ K D K DG I+ L+ + +L ++ I ++++ Sbjct: 272 FEGDTLVNRIELKGIDFKEDG------NILGHKLEYNTRDQLTEEQ-------IAEFKEA 318 Query: 611 YREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNFVRCLVRL 669 + D D GT+ + E+ + G +L +I AD IDF F+ + R Sbjct: 319 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 378 Query: 670 -------EILFKIFKQLDPENTGTI 687 E + + F+ D + G I Sbjct: 379 MKDTDSEEEIREAFRVFDKDGNGYI 403 Score = 38.1 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 40/182 (21%), Positives = 74/182 (40%), Gaps = 21/182 (11%) Query: 422 MGEDMHTIGFGI-YEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPG 480 ED + +G + Y ++LT + + F L + + + T L V+ P Sbjct: 288 FKEDGNILGHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPT 347 Query: 481 EYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQ 540 E L E +G+ I D+ + +++ + +EE+I + FR +F + Sbjct: 348 EAELQDMINEVDADGNGTI--------DFPEFLTMMARKMKDTD-SEEEIREAFR-VFDK 397 Query: 541 LAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 + ISA EL+ ++ + K D E M+ D DG G++ +EF + Sbjct: 398 --DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREADIDGDGQVNYEEFVQM 447 Query: 601 WT 602 T Sbjct: 448 MT 449 >3KF9-A nrPDB Length = 149 Score = 77.0 bits (188), Expect = 3e-14, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 63/150 (42%), Gaps = 21/150 (14%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSI--ETCKIMVDML 584 E+ R F + I A EL+ +R + GF E K M+ + Sbjct: 4 EEQKQEIREAFDLFDTDGSGTIDAKELKVAMRAL----------GFEPKKEEIKKMIADI 53 Query: 585 DEDGSGKLGLKEFYILWT-------KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D+DGSG + +EF + T ++ K +R D D +G ++ +++ +E G Sbjct: 54 DKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGEN 113 Query: 638 LP-CQLHQVIVARFADDELIIDFDNFVRCL 666 + +L ++I D + ++ + F R + Sbjct: 114 MTDEELQEMIDEADRDGDGEVNEEEFFRIM 143 Score = 58.1 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 8/93 (8%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-LPCQLHQVIVARFADDELIIDFDNFV 663 Q+ ++ + D D SGT+++ E++ A+ GF+ ++ ++I D IDF+ F+ Sbjct: 8 QEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTIDFEEFL 67 Query: 664 RCLV-------RLEILFKIFKQLDPENTGTIQL 689 + + E + K F+ D + TG I Sbjct: 68 QMMTAKMGERDSREEIMKAFRLFDDDETGKISF 100 Score = 32.7 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 12/96 (12%) Query: 508 DYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDI 567 D++ + A + E + + E+I FR LF E +IS L+ + + + Sbjct: 62 DFEEFLQMMTAKMGERD-SREEIMKAFR-LFDD--DETGKISFKNLKRVAKEL------- 110 Query: 568 KSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTK 603 + + E + M+D D DG G++ +EF+ + K Sbjct: 111 -GENMTDEELQEMIDEADRDGDGEVNEEEFFRIMKK 145 >1GGZ-A nrPDB Length = 148 Score = 75.8 bits (185), Expect = 6e-14, Method: Composition-based stats. Identities = 33/149 (22%), Positives = 69/149 (46%), Gaps = 17/149 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M+ +D Sbjct: 6 EEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSL--------GQNPTEAELRDMMSEIDR 57 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+G + EF + + ++ ++ +R D D +G +++ E+R + G KL Sbjct: 58 DGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLS 117 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCLV 667 ++ ++I A D + ++++ FVR LV Sbjct: 118 DEEVDEMIRAADTDGDGQVNYEEFVRVLV 146 Score = 51.2 bits (121), Expect = 2e-06, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 36/92 (39%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 + ++++ + D D G + + E+ + G +L ++ D +DF F Sbjct: 9 VTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEF 68 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G + Sbjct: 69 LGMMARKMKDTDNEEEIREAFRVFDKDGNGFV 100 >3U0K-A nrPDB Length = 442 Score = 74.7 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 33/175 (18%), Positives = 76/175 (43%), Gaps = 27/175 (15%) Query: 501 VFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRR 559 V +K ++ D++ E+ F+ F+ + D I+ EL T++R Sbjct: 283 VMQKKTKGWEPTRDQLT----------EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRS 332 Query: 560 VLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI-------QKYQKIYR 612 + + + M++ +D DG G + EF I+ + ++ ++ +R Sbjct: 333 L--------GQNPTEAELQDMINEVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFR 384 Query: 613 EIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFVRCL 666 D D +G +++ E+R + G KL ++ ++I D + ++++ FV+ + Sbjct: 385 VFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 439 Score = 61.2 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD + IDF F Sbjct: 303 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEF 362 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 363 LIMMARKMKDTDSEEEIREAFRVFDKDGNGYI 394 Score = 37.3 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 375 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 423 Query: 586 EDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 424 IDGDGQVNYEEFVQMMT 440 >4OY4-A nrPDB Length = 415 Score = 73.9 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 67/148 (45%), Gaps = 17/148 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 14 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 65 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG G + EF + + ++ ++ +R D D +G +++ E+R + G KL Sbjct: 66 DGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLT 125 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I D + ++++ FV+ + Sbjct: 126 DEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD + IDF F Sbjct: 17 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEF 76 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 77 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 108 Score = 39.6 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 17/110 (15%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 89 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 137 Query: 586 EDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 DG G++ +EF + T + +K+Y R G + ++ AL G Sbjct: 138 IDGDGQVNYEEFVQMMTAKLECEKMYV-----RDGVLTG-DIHMALLLEG 181 >2L1W-A nrPDB Length = 149 Score = 73.9 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 18/155 (11%) Query: 525 ANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDM 583 +EE I D F+ F + D I+ EL T++R + + E + M+ Sbjct: 4 LSEEQIVD-FKEAFGLFDKDGDGCITVEELATVIRSLDQNPTE--------EELQDMISE 54 Query: 584 LDEDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 +D DG+G + EF L K ++ ++ ++ D D++G +++ E+R + G Sbjct: 55 VDADGNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGE 114 Query: 637 KLP-CQLHQVIVARFADDELIIDFDNFVRCLVRLE 670 KL ++ Q+I D + ++++ FV+ ++ + Sbjct: 115 KLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTVR 149 Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 36/97 (37%), Gaps = 8/97 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQ-LHQVIVARFADDELIIDFDNF 662 I +++ + D D G + E+ + + L +I AD I+FD F Sbjct: 9 IVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEF 68 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTIQLDLI 692 + + + E L + FK D + G I + Sbjct: 69 LSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASEL 105 >5UKG-A nrPDB Length = 419 Score = 73.1 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 30/148 (20%), Positives = 65/148 (43%), Gaps = 17/148 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 277 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 328 Query: 587 DGSGKLGLKEFYILWTKIQKYQ-------KIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG G EF + + Y+ + +R D D +G + + E+R + + G KL Sbjct: 329 DGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLT 388 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I D + ++++ FV+ + Sbjct: 389 DEEVDEMIRVADIDGDGQVNYEEFVQMM 416 Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD + DF F Sbjct: 280 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEF 339 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 340 LTMMARKMSYRVTEEEIREAFRVFDKDGNGYI 371 Score = 35.4 bits (80), Expect = 0.090, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 11/78 (14%) Query: 525 ANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDML 584 EE+I + FR +F + + I A EL+ ++ + K D E M+ + Sbjct: 351 VTEEEIREAFR-VFDK--DGNGYIGAAELRHVMTDLGEKLTD--------EEVDEMIRVA 399 Query: 585 DEDGSGKLGLKEFYILWT 602 D DG G++ +EF + T Sbjct: 400 DIDGDGQVNYEEFVQMMT 417 >2GGM-A nrPDB Length = 172 Score = 73.1 bits (178), Expect = 4e-13, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 62/150 (41%), Gaps = 21/150 (14%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSI--ETCKIMVDML 584 E+ R F + I EL+ +R + GF E K M+ + Sbjct: 27 EEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL----------GFEPKKEEIKKMISEI 76 Query: 585 DEDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D++G+GK+ +F + T+ ++ K ++ D D +G ++ +++ +E G Sbjct: 77 DKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGEN 136 Query: 638 LP-CQLHQVIVARFADDELIIDFDNFVRCL 666 L +L ++I D + + F+R + Sbjct: 137 LTDEELQEMIDEADRDGDGEVSEQEFLRIM 166 Score = 31.1 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 37/85 (43%), Gaps = 9/85 (10%) Query: 524 EANEEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 + +E+D + + F ++ +IS L+ + + + + + E + M+D Sbjct: 96 KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL--------GENLTDEELQEMID 147 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKY 607 D DG G++ +EF + K Y Sbjct: 148 EADRDGDGEVSEQEFLRIMKKTSLY 172 >3WFN-B nrPDB Length = 182 Score = 72.7 bits (177), Expect = 5e-13, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 68/148 (45%), Gaps = 17/148 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 13 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 64 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+G + EF + + ++ ++ +R D D +G +++ E+R + G KL Sbjct: 65 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLT 124 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I D + ++++ FV+ + Sbjct: 125 DEEVDEMIREADIDGDGQVNYEEFVQMM 152 Score = 58.9 bits (141), Expect = 8e-09, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 16 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 75 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 76 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 107 Score = 35.8 bits (81), Expect = 0.061, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 37/83 (44%), Gaps = 6/83 (7%) Query: 573 SIETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 S E + + D+DG+G + E + T + ++ ++ RE D+D G +N E Sbjct: 88 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 147 Query: 627 MRKALEEAGFKLPCQLHQVIVAR 649 + + G ++ V++ R Sbjct: 148 FVQMMTAKGGGGGEEVSAVVLQR 170 Score = 35.4 bits (80), Expect = 0.083, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 88 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 136 Query: 586 EDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 137 IDGDGQVNYEEFVQMMT 153 >2F2P-A nrPDB Length = 179 Score = 72.7 bits (177), Expect = 5e-13, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 68/148 (45%), Gaps = 17/148 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 7 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 58 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+G + EF + + ++ ++ +R D D +G +++ E+R + G KL Sbjct: 59 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLT 118 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I D + ++++ FV+ + Sbjct: 119 DEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 58.9 bits (141), Expect = 8e-09, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 70 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 101 Score = 35.4 bits (80), Expect = 0.083, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 82 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 130 Query: 586 EDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 131 IDGDGQVNYEEFVQMMT 147 Score = 32.7 bits (73), Expect = 0.51, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 30/67 (44%), Gaps = 6/67 (8%) Query: 573 SIETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 S E + + D+DG+G + E + T + ++ ++ RE D+D G +N E Sbjct: 82 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 141 Query: 627 MRKALEE 633 + + Sbjct: 142 FVQMMTA 148 >1CLM-A nrPDB Length = 148 Score = 72.7 bits (177), Expect = 5e-13, Method: Composition-based stats. Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 18/153 (11%) Query: 524 EANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 E EE I + F+ FA + D I+ EL T++R + + + M++ Sbjct: 3 ELTEEQIAE-FKEAFALFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMIN 53 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQ-------KIYREIDVDRSGTMNSYEMRKALEEAG 635 +D DG+G + EF L + K Q + ++ D D +G +++ E+R + G Sbjct: 54 EVDADGNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLG 113 Query: 636 FKLP-CQLHQVIVARFADDELIIDFDNFVRCLV 667 KL ++ ++I D + I+++ FVR +V Sbjct: 114 EKLTDDEVDEMIREADIDGDGHINYEEFVRMMV 146 Score = 58.1 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 9 IAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 68 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E L + FK D + G I Sbjct: 69 LSLMARKMKEQDSEEELIEAFKVFDRDGNGLI 100 >6O20-F nrPDB Length = 169 Score = 72.4 bits (176), Expect = 6e-13, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 68/148 (45%), Gaps = 17/148 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 27 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 78 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+G + EF + + ++ ++ +R D D +G +++ E+R + G KL Sbjct: 79 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLT 138 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I D + ++++ FV+ + Sbjct: 139 DEEVDEMIREADIDGDGQVNYEEFVQMM 166 Score = 58.5 bits (140), Expect = 9e-09, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 30 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 89 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 90 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 121 Score = 35.4 bits (80), Expect = 0.090, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 102 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 150 Query: 586 EDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 151 IDGDGQVNYEEFVQMMT 167 >4I2Y-A nrPDB Length = 421 Score = 72.0 bits (175), Expect = 8e-13, Method: Composition-based stats. Identities = 32/175 (18%), Positives = 74/175 (42%), Gaps = 27/175 (15%) Query: 501 VFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRR 559 V +K ++ D++ E+ F+ F+ + D I+ EL T++R Sbjct: 262 VMQKKTMGWEATRDQLT----------EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRS 311 Query: 560 VLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI-------QKYQKIYR 612 + + + M++ +D DG G EF + + ++ ++ +R Sbjct: 312 L--------GQNPTEAELQDMINEVDADGDGTFDFPEFLTMMARKMNDTDSEEEIREAFR 363 Query: 613 EIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFVRCL 666 D D +G + + E+R + + G KL ++ ++I D + ++++ FV+ + Sbjct: 364 VFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 418 Score = 60.0 bits (144), Expect = 3e-09, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD + DF F Sbjct: 282 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEF 341 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 342 LTMMARKMNDTDSEEEIREAFRVFDKDGNGYI 373 Score = 36.2 bits (82), Expect = 0.057, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Query: 524 EANEEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 + N+ D + R F + I A EL+ ++ + K D E M+ Sbjct: 348 KMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTD--------EEVDEMIR 399 Query: 583 MLDEDGSGKLGLKEFYILWT 602 + D DG G++ +EF + T Sbjct: 400 VADIDGDGQVNYEEFVQMMT 419 >2N6A-A nrPDB Length = 173 Score = 72.0 bits (175), Expect = 8e-13, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 68/148 (45%), Gaps = 17/148 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 8 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 59 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+G + EF + + ++ ++ +R D D +G +++ E+R + G KL Sbjct: 60 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLT 119 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I D + ++++ FV+ + Sbjct: 120 DEEVDEMIREADIDGDGQVNYEEFVQMM 147 Score = 58.5 bits (140), Expect = 1e-08, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 11 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 70 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 71 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 102 Score = 35.0 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 83 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 131 Query: 586 EDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 132 IDGDGQVNYEEFVQMMT 148 >4E53-A nrPDB Length = 185 Score = 72.0 bits (175), Expect = 9e-13, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 68/148 (45%), Gaps = 17/148 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 14 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 65 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+G + EF + + ++ ++ +R D D +G +++ E+R + G KL Sbjct: 66 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLT 125 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I D + ++++ FV+ + Sbjct: 126 DEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 58.1 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 17 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 76 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 77 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 108 Score = 37.3 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 11/104 (10%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 89 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 137 Query: 586 EDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 DG G++ +EF + T +I G + +++ Sbjct: 138 IDGDGQVNYEEFVQMMTAKGGGGGAATKIQASFRGHITRKKLKG 181 >2OBH-A nrPDB Length = 143 Score = 71.6 bits (174), Expect = 1e-12, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 62/150 (41%), Gaps = 21/150 (14%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSI--ETCKIMVDML 584 E+ R F + I EL+ +R + GF E K M+ + Sbjct: 2 EEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL----------GFEPKKEEIKKMISEI 51 Query: 585 DEDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D++G+GK+ +F + T+ ++ K ++ D D +G ++ +++ +E G Sbjct: 52 DKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGEN 111 Query: 638 LP-CQLHQVIVARFADDELIIDFDNFVRCL 666 L +L ++I D + + F+R + Sbjct: 112 LTDEELQEMIDEADRDGDGEVSEQEFLRIM 141 Score = 30.4 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 36/81 (44%), Gaps = 9/81 (11%) Query: 524 EANEEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 + +E+D + + F ++ +IS L+ + + + + + E + M+D Sbjct: 71 KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL--------GENLTDEELQEMID 122 Query: 583 MLDEDGSGKLGLKEFYILWTK 603 D DG G++ +EF + K Sbjct: 123 EADRDGDGEVSEQEFLRIMKK 143 >1DTL-A nrPDB Length = 161 Score = 71.6 bits (174), Expect = 1e-12, Method: Composition-based stats. Identities = 35/166 (21%), Positives = 75/166 (45%), Gaps = 20/166 (12%) Query: 512 VDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDG 571 +DD +A +E++ +++ +F L ED IS EL ++ R+L + Sbjct: 1 MDDIYKAAVEQLTEEQKNEFKAAFDIFV-LGAEDGSISTKELGKVM-RMLGQNP------ 52 Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILW----------TKIQKYQKIYREIDVDRSGT 621 + E + M+D +DEDGSG + EF ++ ++ ++R D + G Sbjct: 53 -TPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGY 111 Query: 622 MNSYEMRKALEEAGFKLPCQLHQVIVAR-FADDELIIDFDNFVRCL 666 ++ E++ L+ G + + ++ +++ ID+D F+ + Sbjct: 112 IDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFM 157 Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 11/88 (12%) Query: 619 SGTMNSYEMRKALEEAGFK-LPCQLHQVIVARFADDELIIDFDNFVRCLVRL-------- 669 G++++ E+ K + G P +L ++I D +DFD F+ +VR Sbjct: 33 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGK 92 Query: 670 --EILFKIFKQLDPENTGTIQLDLISWL 695 E L +F+ D G I L+ + + Sbjct: 93 SEEELSDLFRMFDKNADGYIDLEELKIM 120 Score = 33.1 bits (74), Expect = 0.48, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 37/85 (43%), Gaps = 11/85 (12%) Query: 521 EEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIM 580 + +EE++ D FR +F + A D I EL+ +L+ + + + + + Sbjct: 88 DSKGKSEEELSDLFR-MFDKNA--DGYIDLEELKIMLQA--------TGETITEDDIEEL 136 Query: 581 VDMLDEDGSGKLGLKEFYILWTKIQ 605 + D++ G++ EF ++ Sbjct: 137 MKDGDKNNDGRIDYDEFLEFMKGVE 161 >5I0I-E nrPDB Length = 145 Score = 71.2 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 71/149 (47%), Gaps = 19/149 (12%) Query: 528 EDIGDGFRRLFAQLAGEDAE--ISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 E+ F+ F+ LA +D + I+ EL T++R + + + M++ +D Sbjct: 5 EEQIAEFKEAFS-LADKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVD 55 Query: 586 EDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL 638 DG+G + EF + + ++ ++ +R D D +G +++ E+R + G KL Sbjct: 56 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKL 115 Query: 639 P-CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I D + ++++ FV+ + Sbjct: 116 TDEEVDEMIREADIDGDGQVNYEEFVQMM 144 Score = 55.4 bits (132), Expect = 9e-08, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 8 IAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 67 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 68 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 99 Score = 34.6 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 80 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 128 Query: 586 EDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 129 IDGDGQVNYEEFVQMMT 145 >5A2H-A nrPDB Length = 149 Score = 70.4 bits (171), Expect = 3e-12, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 70/149 (46%), Gaps = 17/149 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 +D F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 7 DDQISEFKEAFSLFDKDGDGCITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 58 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+G + EF L + ++ ++ +R D D++G +++ E+R + G KL Sbjct: 59 DGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLT 118 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCLV 667 ++ ++I D + I+++ FV+ ++ Sbjct: 119 DEEVDEMIREADVDGDGQINYEEFVKVMM 147 Score = 56.2 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 37/92 (40%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D G + + E+ + G +L +I AD IDF F Sbjct: 10 ISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E L + F+ D + G I Sbjct: 70 LNLMARKMKDTDSEEELKEAFRVFDKDQNGFI 101 >6HCS-A nrPDB Length = 167 Score = 70.0 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 68/148 (45%), Gaps = 17/148 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 7 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 58 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+G + EF + + ++ ++ +R D D +G +++ E+R + G KL Sbjct: 59 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKLT 118 Query: 640 -CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I D + ++++ FV+ + Sbjct: 119 DEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 58.1 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R E + + F+ D + G I Sbjct: 70 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 101 Score = 33.8 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 11/77 (14%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR +F + + ISA EL+ + + K D E M+ D Sbjct: 82 SEEEIREAFR-VFDK--DGNGYISAAELRHFMTNLGEKLTD--------EEVDEMIREAD 130 Query: 586 EDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 131 IDGDGQVNYEEFVQMMT 147 >5D43-A nrPDB Length = 178 Score = 68.9 bits (167), Expect = 8e-12, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 62/150 (41%), Gaps = 21/150 (14%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSI--ETCKIMVDML 584 ED R F + I EL+ +R + GF E K M+ + Sbjct: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL----------GFEPRKEEMKKMISEV 76 Query: 585 DEDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 D++ +GK+ +F + T+ ++ K +R D D +G ++ +++ E G Sbjct: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES 136 Query: 638 LP-CQLHQVIVARFADDELIIDFDNFVRCL 666 L +L ++I D + ++ + F++ + Sbjct: 137 LTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 Score = 55.8 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 44/93 (47%), Gaps = 8/93 (8%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-LPCQLHQVIVARFADDELIIDFDNFV 663 Q+ ++ + D D SGT++ E++ A+ GF+ ++ ++I + I F++F+ Sbjct: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 Query: 664 RCLVR-------LEILFKIFKQLDPENTGTIQL 689 + + E + K F+ D + TG I Sbjct: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 Score = 35.4 bits (80), Expect = 0.093, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 45/128 (35%), Gaps = 26/128 (20%) Query: 489 FEPHKNGDFCIRVFSEKKADYQTVDDEIEANIE--------EIEANEEDIGDGFRRLFAQ 540 FEP K E K VD E I + E+D + + F Sbjct: 62 FEPRKE---------EMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRL 112 Query: 541 LAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYI 599 ++ +IS L+ + + + + E + M+D D DG G++ +EF Sbjct: 113 FDDDETGKISFKNLKRVANEL--------GESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 Query: 600 LWTKIQKY 607 + K Y Sbjct: 165 IMKKTNLY 172 >2TN4-A nrPDB Length = 159 Score = 67.7 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 68/151 (45%), Gaps = 20/151 (13%) Query: 528 EDIGDGFRRLFAQLAGEDA-EISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E++ F+ F + +IS EL T++R + + E +++ +DE Sbjct: 13 EEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTP--------TKEELDAIIEEVDE 64 Query: 587 DGSGKLGLKEFYILW----------TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 DGSG + +EF ++ ++ +++R D + G +++ E+ + +G Sbjct: 65 DGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRASGE 124 Query: 637 KLPCQLHQVIVAR-FADDELIIDFDNFVRCL 666 + + + ++ +++ IDFD F++ + Sbjct: 125 HVTDEEIESLMKDGDKNNDGRIDFDEFLKMM 155 Score = 43.9 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 36/95 (37%), Gaps = 11/95 (11%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVAR-FADDELIIDFDNF 662 I +++ + D D G ++ E+ + G + I+ D IDF+ F Sbjct: 16 IAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEF 75 Query: 663 VRCLVRL----------EILFKIFKQLDPENTGTI 687 + +VR E L ++F+ D G I Sbjct: 76 LVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYI 110 >1TOP-A nrPDB Length = 162 Score = 65.8 bits (159), Expect = 6e-11, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 67/151 (44%), Gaps = 20/151 (13%) Query: 528 EDIGDGFRRLFAQLAGEDA-EISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E++ F+ F + +IS EL T++ R+L + + E +++ +DE Sbjct: 16 EEMIAEFKAAFDMFDADGGGDISTKELGTVM-RMLGQNP-------TKEELDAIIEEVDE 67 Query: 587 DGSGKLGLKEFYILW----------TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 DGSG + +EF ++ ++ +R D + G ++ E+ + L G Sbjct: 68 DGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGE 127 Query: 637 KLPCQLHQVIVA-RFADDELIIDFDNFVRCL 666 + + + ++ +++ IDFD F++ + Sbjct: 128 HVTEEDIEDLMKDSDKNNDGRIDFDEFLKMM 158 Score = 47.3 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 44/122 (36%), Gaps = 16/122 (13%) Query: 582 DMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQ 641 M D+ + L E I +++ + D D G +++ E+ + G + Sbjct: 2 SMTDQQAEARAFLSE-----EMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKE 56 Query: 642 LHQVIVAR-FADDELIIDFDNFVRCLVRL----------EILFKIFKQLDPENTGTIQLD 690 I+ D IDF+ F+ +VR E L F+ D G I ++ Sbjct: 57 ELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIE 116 Query: 691 LI 692 + Sbjct: 117 EL 118 >3NCG-A nrPDB Length = 486 Score = 63.5 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 65/152 (42%), Gaps = 14/152 (9%) Query: 529 DIGDGFRRLFAQL-AGEDAEISAFELQT-----ILRRVLAKREDIKSDGFSIE-TCKIMV 581 D +F +L D + EL + + + I+++G +IE ++ Sbjct: 328 DETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLM 387 Query: 582 DMLDEDGSGKLGLKEF------YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 +LD DGSG + EF + ++ ++ ++ D D SG +++ E+ K +A Sbjct: 388 PLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKLFSQAD 447 Query: 636 FKLP-CQLHQVIVARFADDELIIDFDNFVRCL 666 + +L +I + + +DF+ FV L Sbjct: 448 SSIQMEELESIIEQVDNNKDGEVDFNEFVEML 479 Score = 47.3 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 40/100 (40%), Gaps = 21/100 (21%) Query: 609 KIYREIDVDRSGTMNSYEMRKA---------------LEEAGFKLPCQLHQVIVARFADD 653 +I+R++D + G ++ E+ + ++ G + Q+ ++ D Sbjct: 335 EIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLLDMDG 394 Query: 654 ELIIDFDNFVR------CLVRLEILFKIFKQLDPENTGTI 687 I++ F+ L+ E + + FK D + +G I Sbjct: 395 SGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKI 434 >5E37-A nrPDB Length = 356 Score = 63.5 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 37/188 (19%), Positives = 75/188 (39%), Gaps = 24/188 (12%) Query: 512 VDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDG 571 +DD +A +EE+E RR + I EL+ +L + + + S Sbjct: 20 MDDASKAKMEELE----------RRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQH 69 Query: 572 FSIE-TCKIMVDMLDEDGSGKLGLKEFYI-------LWTKIQKYQKIYREIDVDRSGTMN 623 + E + ++ D + G + +EF L + +Y+ ++ +D +GT+ Sbjct: 70 WLPEDELERCMEQYDVNKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIG 129 Query: 624 SYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFV----RCLVRLEILFKIFKQ 678 + E+ K G + +L ++ DD I+F F+ L+ L+ + + Sbjct: 130 ATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEFPEFLLMFRNSLLDLKDMT-TYMT 188 Query: 679 LDPENTGT 686 LD G+ Sbjct: 189 LDEAGAGS 196 Score = 39.6 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 30/193 (15%), Positives = 76/193 (39%), Gaps = 16/193 (8%) Query: 466 INLREVLNRFK-LPPGEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDD--EIEANIEE 522 I+ E+ N + + GE ++ + P + C+ + K + ++ +I + Sbjct: 46 IDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVNKDGVISFEEFKQIIYDGLL 105 Query: 523 IEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 +E + F+ + + I A EL + + + S+E ++ Sbjct: 106 LEGTLAEYESAFKAVDKS---GNGTIGATELSKLFASL--------GNPVSLEKLVDLMQ 154 Query: 583 MLDEDGSGKLGLKEFYILW-TKIQKYQKIYREIDVDRSGTMNSYEMRKALE-EAGFKLPC 640 M D+D SG++ EF +++ + + + + +D +G +S + A+E + Sbjct: 155 MYDKDDSGQIEFPEFLLMFRNSLLDLKDMTTYMTLDEAGAGSSGSLVDAVEGDMTLIFSE 214 Query: 641 QLHQVIVARFADD 653 + +++ D Sbjct: 215 EELDALISANPDK 227 >1OQP-A nrPDB Length = 77 Score = 62.7 bits (151), Expect = 5e-10, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDN 661 ++ K +R D D SGT+ ++R+ +E G L +L ++I +D+ ID D Sbjct: 7 SREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDE 66 Query: 662 FVRCL 666 F+R + Sbjct: 67 FIRIM 71 >2LMV-A nrPDB Length = 148 Score = 62.0 bits (149), Expect = 8e-10, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 61/148 (41%), Gaps = 16/148 (10%) Query: 524 EANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDM 583 E EE I + F+ F Q E A L R L + + + ++ Sbjct: 3 ELTEEQIAE-FKDAFVQFDKEGTGKIATRELGTLMRTLGQNP-------TEAELQDLIAE 54 Query: 584 LDEDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 + + +G+L EF + K ++ ++ ++ D D G ++ E+R + G Sbjct: 55 AENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGE 114 Query: 637 KLP-CQLHQVIVARFADDELIIDFDNFV 663 K+ ++ ++I D + +I+++ FV Sbjct: 115 KVTDEEIDEMIREADFDGDGMINYEEFV 142 Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 40/100 (40%), Gaps = 8/100 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I +++ + + D + +G + + E+ + G +L +I ++ ++F F Sbjct: 9 IAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNGQLNFTEF 68 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTIQLDLISWL 695 + + E + + FK D + G I + ++ Sbjct: 69 CGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFV 108 >4DS7-A nrPDB Length = 147 Score = 60.8 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 29/149 (19%), Positives = 60/149 (40%), Gaps = 16/149 (10%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ FA ++ ISA EL T++R + + +++ +D Sbjct: 7 EEQIAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSE--------AEVADLMNEIDV 58 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+ + EF L ++ Q+ + ++ D + G +++ E++ L G KL Sbjct: 59 DGNHAIEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 118 Query: 640 CQLHQVIVARFADDELIIDFDNFVRCLVR 668 ++ +D I+ F L + Sbjct: 119 DAEVDEMLREVSDGSGEINIKQFAALLSK 147 >2LC5-A nrPDB Length = 151 Score = 60.8 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 66/154 (42%), Gaps = 16/154 (10%) Query: 521 EEIEANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKI 579 E+ + + ++ F + D +++A EL T++R + A K Sbjct: 3 EQKKVLTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQK--------ISE 54 Query: 580 MVDMLDEDGSGKLGLKEFYILW-------TKIQKYQKIYREIDVDRSGTMNSYEMRKALE 632 +V D+D SGK + F + + +K + D +++G +++ E++ L Sbjct: 55 IVKDYDKDNSGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLT 114 Query: 633 EAGFKLPCQLHQVIVARFADDELIIDFDNFVRCL 666 G KL Q ++ +E +I+ D+FV+ + Sbjct: 115 TLGEKLTEQEVDDLLKEIGVEEGLINVDDFVKLI 148 >2LHI-A nrPDB Length = 176 Score = 60.4 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 61/149 (40%), Gaps = 16/149 (10%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ FA ++ IS+ EL T++R + + +++ +D Sbjct: 7 EEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSE--------AEVNDLMNEIDV 58 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+ ++ EF L ++ Q+ + ++ D + G +++ E++ L G KL Sbjct: 59 DGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 118 Query: 640 CQLHQVIVARFADDELIIDFDNFVRCLVR 668 ++ +D I+ F L + Sbjct: 119 DAEVDDMLREVSDGSGEINIQQFAALLSK 147 >1LKJ-A nrPDB Length = 146 Score = 59.6 bits (143), Expect = 4e-09, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 61/149 (40%), Gaps = 16/149 (10%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ FA ++ IS+ EL T++R + + +++ +D Sbjct: 6 EEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSE--------AEVNDLMNEIDV 57 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+ ++ EF L ++ Q+ + ++ D + G +++ E++ L G KL Sbjct: 58 DGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 117 Query: 640 CQLHQVIVARFADDELIIDFDNFVRCLVR 668 ++ +D I+ F L + Sbjct: 118 DAEVDDMLREVSDGSGEINIQQFAALLSK 146 >3SIA-A nrPDB Length = 220 Score = 58.5 bits (140), Expect = 9e-09, Method: Composition-based stats. Identities = 26/147 (17%), Positives = 59/147 (40%), Gaps = 6/147 (4%) Query: 532 DGFRRLFAQLAGEDAEISAF-ELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSG 590 D + R++ G D + S E+ ++ + S +T M+ + D D +G Sbjct: 48 DQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRL-----SPQTALRMMRIFDTDFNG 102 Query: 591 KLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARF 650 + EF ++ ++ ++ RSGT+ +E+ AL++ GF + + ++ F Sbjct: 103 HISFYEFMAMYKFMELAYNLFVMNARARSGTLEPHEILPALQQLGFYINQRTSLLLHRLF 162 Query: 651 ADDELIIDFDNFVRCLVRLEILFKIFK 677 A D + ++ ++ Sbjct: 163 ARGMAFCDLNCWIAICAFAAQTRSAYQ 189 >3HZT-A nrPDB Length = 467 Score = 58.5 bits (140), Expect = 9e-09, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 65/153 (42%), Gaps = 13/153 (8%) Query: 529 DIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIE---TCKIMVDML 584 + ++F QL D ++ EL R+++ + D SD S + ++ + Sbjct: 311 EETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSV 370 Query: 585 DEDGSGKLGLKEF------YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL 638 D D +G + EF L ++ +++ D D SG + + E+ + ++ Sbjct: 371 DFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFGVT--EV 428 Query: 639 PCQL-HQVIVARFADDELIIDFDNFVRCLVRLE 670 + HQV+ +++ +DF+ FV + ++ Sbjct: 429 DDETWHQVLQECDKNNDGEVDFEEFVEMMQKIC 461 >1S6I-A nrPDB Length = 188 Score = 57.7 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I +++++ ID D SGT+ E++ L+ G +L ++ ++ A D ID+ F Sbjct: 9 IGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEF 68 Query: 663 VRCLVRL------EILFKIFKQLDPENTGTIQLDLIS 693 + V L E L F D + +G I LD I Sbjct: 69 IAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQ 105 Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 17/149 (11%) Query: 525 ANEEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDM 583 +EE+IG G + LF + ++ I+ EL+ L+RV K ++D Sbjct: 4 LSEEEIG-GLKELFKMIDTDNSGTITFDELKDGLKRV--------GSELMESEIKDLMDA 54 Query: 584 LDEDGSGKLGLKEFYILWTKIQKYQK------IYREIDVDRSGTMNSYEMRKALEEAGFK 637 D D SG + EF + K ++ + D D SG + E+++A ++ G Sbjct: 55 ADIDKSGTIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACKDFGLD 114 Query: 638 LPCQLHQVIVARFADDELIIDFDNFVRCL 666 + +I D++ ID+ F + Sbjct: 115 -DIHIDDMIKEIDQDNDGQIDYGEFAAMM 142 Score = 30.4 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 18/37 (48%), Gaps = 2/37 (5%) Query: 572 FSIETCKI--MVDMLDEDGSGKLGLKEFYILWTKIQK 606 F ++ I M+ +D+D G++ EF + K + Sbjct: 111 FGLDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRKRKG 147 >2AAO-A nrPDB Length = 166 Score = 57.0 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 34/150 (22%), Positives = 68/150 (45%), Gaps = 16/150 (10%) Query: 524 EANEEDIGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 E+ E+ G + +F + A + +I+ EL+ L+RV ++K ++ Sbjct: 19 ESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRV---GANLKES-----EILDLMQ 70 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQK------IYREIDVDRSGTMNSYEMRKALEEAGF 636 D D SG + KEF + K ++ + D D SG + E+++A EE G Sbjct: 71 AADVDNSGTIDYKEFIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQACEEFGV 130 Query: 637 KLPCQLHQVIVARFADDELIIDFDNFVRCL 666 + ++ +++ D++ ID++ FV + Sbjct: 131 E-DVRIEELMRDVDQDNDGRIDYNEFVAMM 159 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 7/97 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ ID D+SG + E++ L+ G L ++ ++ A D+ ID+ F Sbjct: 26 IAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTIDYKEF 85 Query: 663 VRCLVRL------EILFKIFKQLDPENTGTIQLDLIS 693 + + L + LF F D + +G I D + Sbjct: 86 IAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQ 122 >4RGJ-A nrPDB Length = 520 Score = 56.2 bits (134), Expect = 4e-08, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 66/153 (43%), Gaps = 13/153 (8%) Query: 529 DIGDGFRRLFAQLAGE-DAEISAFELQTILRRVL-AKREDIKS-DGFSIE-TCKIMVDML 584 D ++F ++ D ++ EL + +L K ED D +IE +++ + Sbjct: 368 DETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSI 427 Query: 585 DEDGSGKLGLKEFYI------LWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL 638 D D +G + EF L ++ +K ++ D D SG +++ E+ + + + Sbjct: 428 DLDQNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQLFGLS--DV 485 Query: 639 PCQLHQVIVAR-FADDELIIDFDNFVRCLVRLE 670 + + ++ +++ IDF F LV+L Sbjct: 486 SSECWKTVLKEVDQNNDGEIDFKEFRDMLVKLC 518 Score = 43.1 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 49/109 (44%), Gaps = 18/109 (16%) Query: 605 QKYQKIYREIDVDRSGTMNSYEM----RKALEEAGFKLPC--------QLHQVIVARFAD 652 ++ KI++++D + G ++ E+ ++ L+ G ++ Q++ + D Sbjct: 371 KELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSIDLD 430 Query: 653 DELIIDFDNFV------RCLVRLEILFKIFKQLDPENTGTIQLDLISWL 695 I++ F+ + L+ E L K FK D + +G I + ++ L Sbjct: 431 QNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQL 479 >3KHE-A nrPDB Length = 191 Score = 56.2 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 65/153 (42%), Gaps = 13/153 (8%) Query: 529 DIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIE---TCKIMVDML 584 + ++F QL D ++ EL R+++ + D SD S + ++ + Sbjct: 37 EETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSV 96 Query: 585 DEDGSGKLGLKEF------YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL 638 D D +G + EF L ++ +++ D D SG + + E+ + ++ Sbjct: 97 DFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFGVT--EV 154 Query: 639 PCQL-HQVIVARFADDELIIDFDNFVRCLVRLE 670 + HQV+ +++ +DF+ FV + ++ Sbjct: 155 DDETWHQVLQECDKNNDGEVDFEEFVEMMQKIC 187 >2LAP-A nrPDB Length = 167 Score = 55.8 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 43/101 (42%), Gaps = 12/101 (11%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I++ ++ +RE D D+ G +N ++ + G+ +L ++ + +DFD+F Sbjct: 24 IEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDF 83 Query: 663 VRC-----------LVRLEILFKIFKQLDPENTGTIQLDLI 692 V ++ ++ L F++ D G I + Sbjct: 84 VELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSEL 124 Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 26/154 (16%), Positives = 66/154 (42%), Gaps = 22/154 (14%) Query: 529 DIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDED 587 + + R F + + D I+ +L +R + + ++ IE + ++ + Sbjct: 22 EEIEELREAFREFDKDKDGYINCRDLGNCMRTMGY----MPTEMELIE----LSQQINMN 73 Query: 588 GSGKLGLKEFYILWT-----------KIQKYQKIYREIDVDRSGTMNSYEMRKAL-EEAG 635 G + +F L +++ + +RE D + G +++ E+R+A+ + G Sbjct: 74 LGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLG 133 Query: 636 FKLPCQLHQVIVARFA-DDELIIDFDNFVRCLVR 668 ++ + + I+ + + +DF+ FVR + R Sbjct: 134 HQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR 167 >4MVF-A nrPDB Length = 506 Score = 55.4 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 48/97 (49%), Gaps = 7/97 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF-KLPCQLHQVIVARFADDELIIDFDNF 662 I + I+ +DVD SGT++S E+ L++ G+ K+P +HQV+ ++ I + +F Sbjct: 359 INNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDF 418 Query: 663 VRCLVRLEILFKI------FKQLDPENTGTIQLDLIS 693 + + + K FK D + G I ++ + Sbjct: 419 LAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELK 455 Score = 39.6 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 60/151 (39%), Gaps = 18/151 (11%) Query: 530 IGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDG 588 + R +F L +S+ E+ L+++ + I D ++ +D + Sbjct: 358 EINNLRNIFIALDVDNSGTLSSQEILDGLKKI--GYQKIPPD------IHQVLRDIDSNA 409 Query: 589 SGKLGLKEFYILWTKIQKYQKI------YREIDVDRSGTMNSYEMRKALEEAGFK---LP 639 SG++ +F Q Y K ++ D+D +G ++ E+++ + + Sbjct: 410 SGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLID 469 Query: 640 CQLHQVIVARFADDELIIDFDNFVRCLVRLE 670 + ++ + + IDF F+ + +LE Sbjct: 470 KAIDSLLQEVDLNGDGEIDFHEFMLMMSKLE 500 Score = 37.3 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 46/120 (38%), Gaps = 25/120 (20%) Query: 505 KKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGE-------------------D 545 KK YQ + +I + +I++N L A + + + Sbjct: 387 KKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGN 446 Query: 546 AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQ 605 +IS EL+ I R + I + ++ +D +G G++ EF ++ +K++ Sbjct: 447 GKISVEELKRIFGRDDIENPLID------KAIDSLLQEVDLNGDGEIDFHEFMLMMSKLE 500 >3PM8-A nrPDB Length = 197 Score = 55.4 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 48/97 (49%), Gaps = 7/97 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF-KLPCQLHQVIVARFADDELIIDFDNF 662 I + I+ +DVD SGT++S E+ L++ G+ K+P +HQV+ ++ I + +F Sbjct: 56 INNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDF 115 Query: 663 VRCLVRLEILFKI------FKQLDPENTGTIQLDLIS 693 + + + K FK D + G I ++ + Sbjct: 116 LAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELK 152 Score = 36.5 bits (83), Expect = 0.039, Method: Composition-based stats. Identities = 23/144 (15%), Positives = 56/144 (38%), Gaps = 18/144 (12%) Query: 530 IGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDG 588 + R +F L +S+ E+ L+++ + I D ++ +D + Sbjct: 55 EINNLRNIFIALDVDNSGTLSSQEILDGLKKI--GYQKIPPD------IHQVLRDIDSNA 106 Query: 589 SGKLGLKEFYILWTKIQKYQKI------YREIDVDRSGTMNSYEMRKALEEAGFK---LP 639 SG++ +F Q Y K ++ D+D +G ++ E+++ + + Sbjct: 107 SGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLID 166 Query: 640 CQLHQVIVARFADDELIIDFDNFV 663 + ++ + + IDF F+ Sbjct: 167 KAIDSLLQEVDLNGDGEIDFHEFM 190 Score = 35.4 bits (80), Expect = 0.077, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 44/118 (37%), Gaps = 25/118 (21%) Query: 505 KKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGE-------------------D 545 KK YQ + +I + +I++N L A + + + Sbjct: 84 KKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGN 143 Query: 546 AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTK 603 +IS EL+ I R + I + ++ +D +G G++ EF ++ +K Sbjct: 144 GKISVEELKRIFGRDDIENPLID------KAIDSLLQEVDLNGDGEIDFHEFMLMMSK 195 >3FWC-A nrPDB Length = 161 Score = 55.4 bits (132), Expect = 9e-08, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 50/110 (45%), Gaps = 10/110 (9%) Query: 567 IKSDGFSI--ETCKIMVDMLDEDGSGKLGLKEFYILWTK-------IQKYQKIYREIDVD 617 +K+ GF + ++D D +G + +FYI+ + + + ++ ++ D D Sbjct: 49 MKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDD 108 Query: 618 RSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFA-DDELIIDFDNFVRCL 666 +G ++ +R+ +E G L + + ++ F D + I+ + F+ Sbjct: 109 HTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAIC 158 Score = 50.0 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 50/93 (53%), Gaps = 8/93 (8%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFV 663 Q+ + + D++ G ++ +E++ A++ GF+LP ++ +I ++ ++ +D+F Sbjct: 23 QEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFY 82 Query: 664 -----RCLVR--LEILFKIFKQLDPENTGTIQL 689 + L R L+ + + F+ D ++TG I + Sbjct: 83 IVMGEKILKRDPLDEIKRAFQLFDDDHTGKISI 115 >5B8I-B nrPDB Length = 171 Score = 55.0 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 34/152 (22%), Positives = 62/152 (40%), Gaps = 25/152 (16%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 + E++ ++R ++ + TI R + S+ S M+ + D Sbjct: 16 DHEEVDRLWKRF--------MKLDRDKSGTIERDEFLSLPQVSSNPLST----RMIAIFD 63 Query: 586 EDGSGKLGLKE-------FYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA-GFK 637 EDG G + +E F K +K + ++ D+DR G +++ E+ L+ G Sbjct: 64 EDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSN 123 Query: 638 LPC-QLHQV----IVARFADDELIIDFDNFVR 664 L QL Q+ I+ D + I F+ F R Sbjct: 124 LKDMQLQQIVDKTIMEADLDGDGRISFEEFTR 155 Score = 44.6 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 24/102 (23%), Positives = 38/102 (37%), Gaps = 17/102 (16%) Query: 593 GLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFAD 652 +E LW + + ++D D+SGT+ E + + L + +I D Sbjct: 16 DHEEVDRLWKR-------FMKLDRDKSGTIERDEFLSLPQVSSNPLSTR---MIAIFDED 65 Query: 653 DELIIDFDNFVRCLV-------RLEILFKIFKQLDPENTGTI 687 +DF FV L + E L FK D + G I Sbjct: 66 GGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFI 107 >1IJ5-A nrPDB Length = 323 Score = 54.6 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 34/164 (20%), Positives = 69/164 (42%), Gaps = 19/164 (11%) Query: 528 EDIGDGFRRLF--AQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 E+ + R+LF + ++G + S +L+ +L + + K + M++ Sbjct: 118 EEDTNILRQLFLSSAVSGS-GKFSFQDLKQVLAKYADTIPEGP--------LKKLFVMVE 168 Query: 586 EDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQV 645 D G++ + + +R+ID + +GT++ E R+ GF + Q Sbjct: 169 NDTKGRMSYITLVAVANDLAALVADFRKIDTNSNGTLSRKEFREHFVRLGF--DKKSVQD 226 Query: 646 IVARFADDELI--IDFDNFVR---CLVRLEILFKIFKQLDPENT 684 + R+AD++ + F +V CL+ L IL+ F D Sbjct: 227 ALFRYADEDESDDVGFSEYVHLGLCLLVLRILY-AFADFDKSGQ 269 Score = 37.7 bits (86), Expect = 0.016, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 6/83 (7%) Query: 585 DEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQ 644 DED S +G E+ L + + +Y D D+SG ++ E++K LE+A +P + Sbjct: 233 DEDESDDVGFSEYVHLGLCLLVLRILYAFADFDKSGQLSKEEVQKVLEDA--HIPESARK 290 Query: 645 VIVARFA----DDELIIDFDNFV 663 +F+ DD + + FV Sbjct: 291 KFEHQFSVVDVDDSKSLSYQEFV 313 >3Q5I-A nrPDB Length = 504 Score = 54.6 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 58/151 (38%), Gaps = 12/151 (7%) Query: 529 DIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIET-CKIMVDMLDE 586 + +F +L D ++ EL VL ++ + ++E ++ +D Sbjct: 352 EERKELTDIFKKLDKNGDGQLDKKELIEGYN-VLRNFKNELGELKNVEEEVDNILKEVDF 410 Query: 587 DGSGKLGLKEF------YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC 640 D +G + EF + ++ ++ + D D+SG + E+ + Sbjct: 411 DKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLFGLT--SISE 468 Query: 641 QLH-QVIVARFADDELIIDFDNFVRCLVRLE 670 + V+ + + +IDFD FV + ++ Sbjct: 469 KTWNDVLGEADQNKDNMIDFDEFVSMMHKIC 499 Score = 44.6 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 23/133 (17%), Positives = 51/133 (38%), Gaps = 21/133 (15%) Query: 577 CKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQK------IYREIDVDRSGTMNSYEM--- 627 C + +M +GS KL + +K+ ++ I++++D + G ++ E+ Sbjct: 321 CGALSNMRKFEGSQKLAQAAILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEG 380 Query: 628 ----RKALEEAGF--KLPCQLHQVIVARFADDELIIDFDNFVRCLV------RLEILFKI 675 R E G + ++ ++ D I++ F+ + E L + Sbjct: 381 YNVLRNFKNELGELKNVEEEVDNILKEVDFDKNGYIEYSEFISVCMDKQILFSEERLRRA 440 Query: 676 FKQLDPENTGTIQ 688 F D + +G I Sbjct: 441 FNLFDTDKSGKIT 453 >4YZB-A nrPDB Length = 491 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 32/160 (20%), Positives = 71/160 (44%), Gaps = 13/160 (8%) Query: 522 EIEANEEDIGDGFRRLFAQLAGE-DAEISAFELQ-TILRRVLAKREDIKS-DGFSIE-TC 577 ++ NEE + ++F ++ D ++ EL + + K ED+ + D +IE Sbjct: 331 KLTTNEETVE--LNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEV 388 Query: 578 KIMVDMLDEDGSGKLGLKEFYIL------WTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631 + ++D +D D +G + EF + Q+ ++ + D D SG ++S E+ Sbjct: 389 EQVLDAVDFDKNGFIEYSEFVTVAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIF 448 Query: 632 EEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEI 671 + +V+ +++ +DF+ F + L++L Sbjct: 449 GVSEVD-SETWRRVLAEVDRNNDGEVDFEEFRQMLLKLCG 487 Score = 36.2 bits (82), Expect = 0.049, Method: Composition-based stats. Identities = 35/190 (18%), Positives = 73/190 (38%), Gaps = 30/190 (15%) Query: 528 EDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKI-MVDMLDE 586 E D R++ A + ISA + L K D +D + + + ++++ Sbjct: 260 EPAKDLIRKMLAYVP--TMRISARD---ALEHEWLKTTDAATDSIDVPSLESTILNIRQF 314 Query: 587 DGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYEMRKALEEA----GF 636 G+ KL + +K+ + KI++ +D + G ++ E+ + E G Sbjct: 315 QGTQKLAAAALLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGE 374 Query: 637 KLPC--------QLHQVIVARFADDELIIDFDNFV------RCLVRLEILFKIFKQLDPE 682 + ++ QV+ A D I++ FV + L+ + L + F D + Sbjct: 375 DVSALDQSAIEFEVEQVLDAVDFDKNGFIEYSEFVTVAMDRKTLLSRQRLERAFGMFDAD 434 Query: 683 NTGTIQLDLI 692 +G I + Sbjct: 435 GSGKISSSEL 444 >4JWQ-A nrPDB Length = 199 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFV 663 +Q+ + ++ +D D G + +++K LE +G KLP ++ +D ID+ F+ Sbjct: 57 LQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEFL 116 Query: 664 RCLVRLEILFK-----IFKQLDPENTGTIQ 688 + + L K F+ D +N G I Sbjct: 117 AAALDRKHLSKKLIYCAFRVFDVDNDGEIT 146 Score = 49.2 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 31/151 (20%), Positives = 58/151 (38%), Gaps = 22/151 (14%) Query: 532 DGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSG 590 + +F L + I+ +L+ L K F + ++D +D DGSG Sbjct: 58 QQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLP----QNFDV-----LLDQIDSDGSG 108 Query: 591 KLGLKEFYILWTKIQKYQK-----IYREIDVDRSGTMNSYEMRKALEEAGFKLP------ 639 ++ EF + K +R DVD G + + E+ L K Sbjct: 109 RIDYTEFLAAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGSITQKDV 168 Query: 640 CQLHQVIVARFADDELIIDFDNFVRCLVRLE 670 Q+ ++I +++ IDF F +++L+ Sbjct: 169 NQVKKMIQEVDKNNDGKIDFYEF-CEMMKLK 198 >5JN2-A nrPDB Length = 525 Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 29/158 (18%), Positives = 65/158 (41%), Gaps = 11/158 (6%) Query: 524 EANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVL-AKREDIKS-DGFSIE-TCKI 579 + +D +F ++ D ++ EL + ++ K +D D ++E Sbjct: 368 KLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQ 427 Query: 580 MVDMLDEDGSGKLGLKEFYIL------WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEE 633 ++D +D D +G + EF + ++ ++ +R D D SG ++S E+ Sbjct: 428 VLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGV 487 Query: 634 AGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEI 671 + V+ +++ +DFD F + L++L Sbjct: 488 SDVD-SETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCG 524 Score = 35.4 bits (80), Expect = 0.077, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 40/96 (41%), Gaps = 14/96 (14%) Query: 506 KADYQTVDDEIEANIEEIEA-NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKR 564 K Y + + ++ + E + FR + +G+ IS+ EL TI Sbjct: 436 KNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGK---ISSTELATIFGV----- 487 Query: 565 EDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 D+ S ET K ++ +D++ G++ EF + Sbjct: 488 SDVDS-----ETWKSVLSEVDKNNDGEVDFDEFQQM 518 >4ZCV-A nrPDB Length = 165 Score = 53.9 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 58/144 (40%), Gaps = 11/144 (7%) Query: 522 EIEANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIM 580 E + + + LF L D + ELQ LR + + + + Sbjct: 3 EDACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNL--------GIPLGQDAEEKI 54 Query: 581 VDMLDEDGSGKLGLKEF-YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 D + GKL +EF L +K + ++ +D + G + + E+ ++L+ G + Sbjct: 55 FTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTIS 114 Query: 640 CQLHQVIVARFA-DDELIIDFDNF 662 Q ++I+ D + +D++ + Sbjct: 115 EQQAELILQSIDVDGTMTVDWNEW 138 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 2/90 (2%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVI-VARFADDELIIDFDNFV 663 +Y+ +++ +D + G ++ E+++ L G L + I + + +DF+ F+ Sbjct: 13 TRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFM 72 Query: 664 RCLVRLEI-LFKIFKQLDPENTGTIQLDLI 692 + L E + FK LD N G I+ I Sbjct: 73 KYLKDHEKKMKLAFKSLDKNNDGKIEASEI 102 >4ORC-B nrPDB Length = 170 Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 66/150 (44%), Gaps = 26/150 (17%) Query: 527 EEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 + D + F +L ++ +S E ++ +++ + + ++D+ D Sbjct: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSL--------PELQQNPL----VQRVIDIFD 63 Query: 586 EDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEA-GFK 637 DG+G++ KEF ++ QK + +R D+D+ G +++ E+ + L+ G Sbjct: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNN 123 Query: 638 LPC-QLHQV----IVARFADDELIIDFDNF 662 L QL Q+ I+ D + I F+ F Sbjct: 124 LKDTQLQQIVDKTIINADKDGDGRISFEEF 153 >4N5X-A nrPDB Length = 199 Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 26/141 (18%), Positives = 58/141 (41%), Gaps = 11/141 (7%) Query: 525 ANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDM 583 + + + + LF L D + ELQ LR + + + + Sbjct: 15 SQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNL--------GIPLGQDAEEKIFTT 66 Query: 584 LDEDGSGKLGLKEF-YILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 D + GKL +EF L +K + ++ +D + G + + E+ ++L+ G + Q Sbjct: 67 GDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQ 126 Query: 643 HQVIVARFA-DDELIIDFDNF 662 ++I+ D + +D++ + Sbjct: 127 AELILQSIDVDGTMTVDWNEW 147 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 2/90 (2%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVI-VARFADDELIIDFDNFV 663 +Y+ +++ +D + G ++ E+++ L G L + I + + +DF+ F+ Sbjct: 22 TRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFM 81 Query: 664 RCLVRLEI-LFKIFKQLDPENTGTIQLDLI 692 + L E + FK LD N G I+ I Sbjct: 82 KYLKDHEKKMKLAFKSLDKNNDGKIEASEI 111 >2AMI-A nrPDB Length = 96 Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 45/90 (50%), Gaps = 6/90 (6%) Query: 578 KIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 K +V + G++GL E + Q+ ++ + D D SGT+++ E++ A+ GF+ Sbjct: 8 KTVVSARRDQKKGRVGLTE-----EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFE 62 Query: 638 -LPCQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I D IDF+ F+ + Sbjct: 63 PKKEEIKKMISEIDKDGSGTIDFEEFLTMM 92 Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 13/78 (16%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSI--ETCKIMVDML 584 E+ R F + I A EL+ +R + GF E K M+ + Sbjct: 26 EEQKQEIREAFDLFDTDGSGTIDAKELKVAMRAL----------GFEPKKEEIKKMISEI 75 Query: 585 DEDGSGKLGLKEFYILWT 602 D+DGSG + +EF + T Sbjct: 76 DKDGSGTIDFEEFLTMMT 93 Score = 38.1 bits (87), Expect = 0.013, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 575 ETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 + + D+ D DGSG + KE + + ++ +K+ EID D SGT++ E Sbjct: 30 QEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEE 87 >2BL0-C nrPDB Length = 142 Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 57/144 (39%), Gaps = 16/144 (11%) Query: 528 EDIGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 +D F+ F + I+ LQT+L++ ++ F+ M + D Sbjct: 2 DDQVSEFKEAFELFDSERTGFITKEGLQTVLKQF---GVRVEPAAFN-----EMFNEADA 53 Query: 587 DGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 G+GK+ EF + + K ++ +R D + +G + ++ AL G +L Sbjct: 54 TGNGKIQFPEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNLGDRLK 113 Query: 640 CQLHQVIVARFADDELIIDFDNFV 663 + ++ I +DNF+ Sbjct: 114 PHEFAEFLGITETEKGQIRYDNFI 137 Score = 49.6 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 40/92 (43%), Gaps = 8/92 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQ-VIVARFADDELIIDFDNF 662 + ++++ + D +R+G + ++ L++ G ++ + A I F F Sbjct: 5 VSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQFPEF 64 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTI 687 + + R +IL + F+ DPE TG I Sbjct: 65 LSMMGRRMKQTTSEDILRQAFRTFDPEGTGYI 96 >2HF5-A nrPDB Length = 68 Score = 52.7 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 33/68 (48%), Gaps = 7/68 (10%) Query: 575 ETCKIMVDMLDEDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEM 627 + M++ +D DG+G + EF + + ++ ++ +R D D +G +++ E+ Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 Query: 628 RKALEEAG 635 R + G Sbjct: 61 RHVMTNLG 68 Score = 36.5 bits (83), Expect = 0.037, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 22/54 (40%), Gaps = 7/54 (12%) Query: 641 QLHQVIVARFADDELIIDFDNFVRCLVRL-------EILFKIFKQLDPENTGTI 687 +L +I AD IDF F+ + R E + + F+ D + G I Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 55 >5ZOR-A nrPDB Length = 149 Score = 52.3 bits (124), Expect = 7e-07, Method: Composition-based stats. Identities = 22/153 (14%), Positives = 55/153 (35%), Gaps = 22/153 (14%) Query: 531 GDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFS---IETCKIMVDMLDE 586 + R F + I A E+ + K GF + + V ++ Sbjct: 6 DEQIREAFNLFDADGSGAIDAEEMALAM----------KGLGFGDLPRDEVERTVRSMNT 55 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 + +G + EF + ++ K ++ D+D+ G ++ +++ + G Sbjct: 56 NANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPG 115 Query: 640 CQ-LHQVIVARFADDELIIDFDNFVRCLVRLEI 671 L ++I D + + F+ F ++++ Sbjct: 116 DDVLQEMIAEADEDGDGEVSFEEFKSVMMQMRG 148 Score = 38.5 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 11/95 (11%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF-KLPCQLHQVIVARFADD-ELIIDFDNF 662 ++ ++ + D D SG +++ EM A++ GF LP + V + +I++ F Sbjct: 7 EQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYGEF 66 Query: 663 VRCLVRL--------EILFKIFKQLDPENTGTIQL 689 R +V+ E + K F+ D + G I Sbjct: 67 ER-MVKSRMAQKDSPEEVLKAFQLFDLDKKGKISF 100 Score = 31.9 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 18/105 (17%), Positives = 42/105 (40%), Gaps = 12/105 (11%) Query: 514 DEIEANIEEIEANEE------DIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDI 567 DE+E + + N + + AQ + + AF+L + ++ ++ Sbjct: 44 DEVERTVRSMNTNANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANL 103 Query: 568 K------SDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQK 606 K + + + M+ DEDG G++ +EF + +++ Sbjct: 104 KEVAKLLGENPGDDVLQEMIAEADEDGDGEVSFEEFKSVMMQMRG 148 >5H7D-E nrPDB Length = 120 Score = 51.9 bits (123), Expect = 8e-07, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 30/68 (44%), Gaps = 1/68 (1%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFD 660 +IQ +++ + D D GT+ + E+ + G +L +I AD IDF Sbjct: 53 NQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 112 Query: 661 NFVRCLVR 668 F+ + R Sbjct: 113 EFLTMMAR 120 Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 45/114 (39%), Gaps = 15/114 (13%) Query: 491 PHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGE-DAEIS 549 P+ NG S +DD ++ EA + + F+ F+ + D I+ Sbjct: 21 PNLNGRQVAAFIS------SLLDDPSQSANLLAEAKKLNQIQAFKEAFSLFDKDGDGTIT 74 Query: 550 AFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTK 603 EL T++R + + + M++ +D DG+G + EF + + Sbjct: 75 TKELGTVMRSL--------GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 120 Score = 31.5 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 6/59 (10%) Query: 574 IETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 I+ K + D+DG G + KE + + + Q + E+D D +GT++ E Sbjct: 55 IQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 113 >1SR6-C nrPDB Length = 156 Score = 51.9 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 60/154 (38%), Gaps = 22/154 (14%) Query: 524 EANEEDIGD--GFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMV 581 + ++++I D LF G D + AF+L + R + + D F++ M Sbjct: 2 KLSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRN--EDVFAVGGTHKM- 58 Query: 582 DMLDEDGSGKLGLKEFYILWTKIQK--------YQKIYREIDVDRSGTMNSYEMRKALEE 633 G L +EF + + Y + ++ D + G ++ E+R L Sbjct: 59 ------GEKSLPFEEFLPAYEGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTA 112 Query: 634 AGFKLPCQLHQVIVARFA---DDELIIDFDNFVR 664 G +L + I+ D E + +++FV+ Sbjct: 113 LGERLSDEDVDEIIKLTDLQEDLEGNVKYEDFVK 146 >2LV7-A nrPDB Length = 100 Score = 51.9 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFA-DDELIIDFDNF 662 +++ ++ ++ D D +G ++ E+ A+ G+ +VI+ R D + +DF+ F Sbjct: 35 LEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEEF 94 Query: 663 VRCL 666 V L Sbjct: 95 VTLL 98 Score = 31.1 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 9/74 (12%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 ED + R F + IS EL T +R + + ++++ LD Sbjct: 32 EDELEEIREAFKVFDRDGNGFISKQELGTAMRSL--------GYMPNEVELEVIIQRLDM 83 Query: 587 DGSGKLGLKEFYIL 600 DG G++ +EF L Sbjct: 84 DGDGQVDFEEFVTL 97 >3O4Y-A nrPDB Length = 196 Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 5/100 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFV 663 +QK + + +D + G + ++RK LE +G LP ++ +D ID+ F+ Sbjct: 54 VQKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNFDLLLDQIDSDGSGNIDYTEFL 113 Query: 664 RCLVRLEILFK-----IFKQLDPENTGTIQLDLISWLSFS 698 + L K F+ D +N G I ++ + F+ Sbjct: 114 AAAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFN 153 Score = 45.4 bits (106), Expect = 8e-05, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 39/98 (39%), Gaps = 11/98 (11%) Query: 580 MVDMLDEDGSGKLGLKEFYILWTKIQKYQK-----IYREIDVDRSGTMNSYEMRKALEEA 634 ++D +D DGSG + EF ++ K +R DVD G + + E+ L Sbjct: 95 LLDQIDSDGSGNIDYTEFLAAAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNG 154 Query: 635 GFKLP------CQLHQVIVARFADDELIIDFDNFVRCL 666 + Q+ ++I + + IDF F + Sbjct: 155 NKRGNITERDVNQVKKMIREVDKNGDGKIDFYEFSEMM 192 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 39/101 (38%), Gaps = 14/101 (13%) Query: 511 TVDDEIEANIEEIEANEEDIGDGFRRLFAQL---------AGEDAEISAFELQTILRRVL 561 +D + NI+ E I R+L +L D EI+ EL +L Sbjct: 98 QIDSDGSGNIDYTEFLAAAIDR--RQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNGN 155 Query: 562 AKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWT 602 + + D + K M+ +D++G GK+ EF + Sbjct: 156 KRGNITERD---VNQVKKMIREVDKNGDGKIDFYEFSEMMK 193 >5OTJ-D nrPDB Length = 110 Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 28/61 (45%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRC 665 ++I++ D + G ++ E+ AL G ++ +++ D + IDF+ F+ Sbjct: 4 DMERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISF 63 Query: 666 L 666 Sbjct: 64 C 64 Score = 37.7 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 10/67 (14%) Query: 532 DGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSG 590 D R+F + D +IS EL LR + + S + + M+ +D DG G Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLGST---------SADEVQRMMAEIDTDGDG 53 Query: 591 KLGLKEF 597 + EF Sbjct: 54 FIDFNEF 60 >2JNF-A nrPDB Length = 158 Score = 51.2 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 12/103 (11%) Query: 576 TCKIMVDMLDEDGSGKLGLKEFYILWTKI-----------QKYQKIYREIDVDRSGTMNS 624 T + ++D D G+G + F I+ + Q+ ++ +R D + +G +++ Sbjct: 51 TIRQLIDEFDPFGNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYIST 110 Query: 625 YEMRKALEEAGFKLPCQLHQ-VIVARFADDELIIDFDNFVRCL 666 MR+ L E L + +I AD +DF+ F+ + Sbjct: 111 DVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVM 153 Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 43/104 (41%), Gaps = 13/104 (12%) Query: 602 TKIQKYQKIYREIDV-DRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFAD-DELIIDF 659 +++ + +R+ + + SG +++ ++ LE G + + ++ F IDF Sbjct: 10 NQVKLLETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLIDEFDPFGNGDIDF 69 Query: 660 DNFVRCLVRL-----------EILFKIFKQLDPENTGTIQLDLI 692 D+F R + L + F+ D E G I D++ Sbjct: 70 DSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVM 113 Score = 37.7 bits (86), Expect = 0.016, Method: Composition-based stats. Identities = 30/115 (26%), Positives = 44/115 (38%), Gaps = 20/115 (17%) Query: 489 FEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGED-AE 547 F+P NGD I S K + + +E+ N E + R F E Sbjct: 59 FDPFGNGD--IDFDSFKIIGARFLGEEV---------NPEQMQQELREAFRLYDKEGNGY 107 Query: 548 ISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWT 602 IS ++ IL + S E M+D +D DGSG + +EF + T Sbjct: 108 ISTDVMREILAELDET--------LSSEDLDAMIDEIDADGSGTVDFEEFMGVMT 154 >2LVK-A nrPDB Length = 77 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 28/61 (45%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRC 665 ++I++ D + G ++ E+ AL G ++ +++ D + IDF+ F+ Sbjct: 3 DMERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISF 62 Query: 666 L 666 Sbjct: 63 C 63 Score = 36.9 bits (84), Expect = 0.029, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 10/67 (14%) Query: 532 DGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSG 590 D R+F + D +IS EL LR + + S + + M+ +D DG G Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGST---------SADEVQRMMAEIDTDGDG 52 Query: 591 KLGLKEF 597 + EF Sbjct: 53 FIDFNEF 59 >2LHH-A nrPDB Length = 128 Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 52/121 (42%), Gaps = 16/121 (13%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ FA ++ IS+ EL T++R + + +++ +D Sbjct: 6 EEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSE--------AEVNDLMNEIDV 57 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 DG+ ++ EF L ++ Q+ + ++ D + G +++ E++ L G KL Sbjct: 58 DGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 117 Query: 640 C 640 Sbjct: 118 D 118 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 43/104 (41%), Gaps = 8/104 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D +G+++S E+ + G +++ ++ D I+F F Sbjct: 9 IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEF 68 Query: 663 VRCLVRL-------EILFKIFKQLDPENTGTIQLDLISWLSFSV 699 + + R + L + FK D G I + + S+ Sbjct: 69 LALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI 112 >2I08-A nrPDB Length = 78 Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 9 IAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFPEF 68 Query: 663 VRCLVRL 669 + + R+ Sbjct: 69 LTMMARI 75 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 36/81 (44%), Gaps = 9/81 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 6 EEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTE--------AELQDMINEVDA 57 Query: 587 DGSGKLGLKEFYILWTKIQKY 607 DG+G + EF + +I KY Sbjct: 58 DGNGTIDFPEFLTMMARIMKY 78 >5COC-A nrPDB Length = 130 Score = 50.0 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 62 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 121 Query: 663 VRCLVR 668 + + R Sbjct: 122 LTMMAR 127 Score = 39.2 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 37/85 (43%), Gaps = 9/85 (10%) Query: 520 IEEIEANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCK 578 + + +A E+ F+ F+ + D I+ EL T++R + + + Sbjct: 51 LNDAQAAAEECIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQ 102 Query: 579 IMVDMLDEDGSGKLGLKEFYILWTK 603 M++ +D DG+G + EF + + Sbjct: 103 DMINEVDADGNGTIDFPEFLTMMAR 127 Score = 35.8 bits (81), Expect = 0.069, Method: Composition-based stats. Identities = 28/110 (25%), Positives = 41/110 (37%), Gaps = 19/110 (17%) Query: 525 ANEEDIGDGFRRLFAQLAGEDAEISAFELQ--TILRRVLAKREDIKSDGFSIETCKIMVD 582 NEE R F Q +D SA L L A E+ I K Sbjct: 22 LNEEQ-----RNAFIQSLKDDPSQSANLLAEAKCLNDAQAAAEEC------IAEFKEAFS 70 Query: 583 MLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 + D+DG G + KE + + + Q + E+D D +GT++ E Sbjct: 71 LFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 120 >2M29-A nrPDB Length = 171 Score = 49.6 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 37/185 (20%), Positives = 68/185 (36%), Gaps = 38/185 (20%) Query: 495 GDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQ 554 G R+F + + +E++A EE + + +D I EL Sbjct: 9 GPLLNRMFGKDRELGPEELEELQAAFEEFDTD-----------------QDGYIGYRELG 51 Query: 555 TILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL-----------WTK 603 +R + + ++ + V M G + +EF L Sbjct: 52 DCMRTLGY----MPTEM-ELLEVSQHVKM---RMGGFVDFEEFVELISPKLREETAHMLG 103 Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEE-AGFKLP-CQLHQVIVARFADDELIIDFDN 661 +++ + +RE D DR G + E+R+A G L +L +++ + + IDFD Sbjct: 104 VRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTIDFDE 163 Query: 662 FVRCL 666 FV L Sbjct: 164 FVMML 168 Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 36/97 (37%), Gaps = 12/97 (12%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNFVRC- 665 Q + E D D+ G + E+ + G+ +L +V +DF+ FV Sbjct: 31 QAAFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELI 90 Query: 666 ----------LVRLEILFKIFKQLDPENTGTIQLDLI 692 ++ + L F++ D + G I + + Sbjct: 91 SPKLREETAHMLGVRELRIAFREFDKDRDGRITVAEL 127 >2N7L-C nrPDB Length = 141 Score = 48.9 bits (115), Expect = 8e-06, Method: Composition-based stats. Identities = 26/96 (27%), Positives = 48/96 (50%), Gaps = 9/96 (9%) Query: 511 TVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSD 570 ++DD +A +E++ +++ +F L ED IS EL ++ R+L + Sbjct: 15 SMDDIYKAAVEQLTEEQKNEFKAAFDIFV-LGAEDGSISTKELGKVM-RMLGQNP----- 67 Query: 571 GFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQK 606 + E + M+D +DEDGSG + EF ++ + K Sbjct: 68 --TPEELQEMIDEVDEDGSGTVDFDEFLVMMVRXMK 101 Score = 38.1 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 619 SGTMNSYEMRKALEEAGFK-LPCQLHQVIVARFADDELIIDFDNFVRCLVR 668 G++++ E+ K + G P +L ++I D +DFD F+ +VR Sbjct: 48 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVR 98 >1M39-A nrPDB Length = 89 Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 36/83 (43%), Gaps = 8/83 (9%) Query: 592 LGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLH 643 + +F + T+ ++ K ++ D D +G ++ +++ +E G L +L Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQ 60 Query: 644 QVIVARFADDELIIDFDNFVRCL 666 ++I D + + F+R + Sbjct: 61 EMIDEADRDGDGEVSEQEFLRIM 83 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 37/85 (43%), Gaps = 9/85 (10%) Query: 524 EANEEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 + +E+D + + F ++ +IS L+ + + + + + E + M+D Sbjct: 13 KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL--------GENLTDEELQEMID 64 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKY 607 D DG G++ +EF + K Y Sbjct: 65 EADRDGDGEVSEQEFLRIMKKTSLY 89 >5VLN-A nrPDB Length = 120 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 10/124 (8%) Query: 512 VDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDG 571 +DD +A +E++ +++ +F L ED IS EL ++ R+L + Sbjct: 1 MDDIYKAAVEQLTEEQKNEFKAAFDIFV-LGAEDGSISTKELGKVM-RMLGQNP------ 52 Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILW-TKIQKYQKIYREIDVDRSGTMNSYEMRKA 630 + E + M+D +DEDGSG + EF ++ ++ K + R +++ M +A Sbjct: 53 -TPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKFKRPTLRRVRISADAMMQA 111 Query: 631 LEEA 634 L A Sbjct: 112 LLGA 115 Score = 38.1 bits (87), Expect = 0.013, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 619 SGTMNSYEMRKALEEAGFK-LPCQLHQVIVARFADDELIIDFDNFVRCLVR 668 G++++ E+ K + G P +L ++I D +DFD F+ +VR Sbjct: 33 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVR 83 >4Q57-A nrPDB Length = 65 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 28/64 (43%), Gaps = 1/64 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 1 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 60 Query: 663 VRCL 666 + + Sbjct: 61 LTMM 64 Score = 34.6 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 30/71 (42%), Gaps = 9/71 (12%) Query: 533 GFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGK 591 F+ F+ + D I+ EL T++R + + + M++ +D DG+G Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDADGNGT 54 Query: 592 LGLKEFYILWT 602 + EF + Sbjct: 55 IDFPEFLTMMA 65 Score = 32.7 bits (73), Expect = 0.62, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 26/59 (44%), Gaps = 6/59 (10%) Query: 574 IETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 I K + D+DG G + KE + + + Q + E+D D +GT++ E Sbjct: 1 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 59 >2JOJ-A nrPDB Length = 77 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 40/77 (51%), Gaps = 7/77 (9%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL-PCQLHQVIVARFADDELIIDFDNFV 663 Q+ ++ + D +++G+++ +E++ A+ GF + ++ +++ + I FD+F Sbjct: 7 QEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDF- 65 Query: 664 RCLVRLEILFKIFKQLD 680 L+I+ + K D Sbjct: 66 -----LDIMTEKIKNRD 77 >2OPO-A nrPDB Length = 86 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 30/59 (50%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNF 662 I ++I++ D + G ++S E+ AL+ G P ++ +++ D + I FD F Sbjct: 10 IADRERIFKRFDTNGDGKISSSELGDALKTLGSVTPDEVRRMMAEIDTDGDGFISFDEF 68 Score = 35.4 bits (80), Expect = 0.078, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 11/77 (14%) Query: 524 EANEEDIGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 E +DI D R+F + D +IS+ EL L+ + + D + M+ Sbjct: 4 EDTPQDIADR-ERIFKRFDTNGDGKISSSELGDALKTLGSVTPD---------EVRRMMA 53 Query: 583 MLDEDGSGKLGLKEFYI 599 +D DG G + EF Sbjct: 54 EIDTDGDGFISFDEFTD 70 >4WPX-A nrPDB Length = 177 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARF-ADDELIIDFDNF 662 + ++ +R DVD G + ++RK ++ G +P Q ++ F ++ + +D D F Sbjct: 110 RDELRRAFRLFDVDGKGMITEDDLRKVCQQVGNNIPDADIQAMIEEFDSNGKGGVDEDEF 169 Query: 663 VRCLV 667 +R ++ Sbjct: 170 LRLMM 174 Score = 36.2 bits (82), Expect = 0.045, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 34/104 (32%), Gaps = 20/104 (19%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIV---------------- 647 + + + D ++ G ++ E R L GF LP Q + ++V Sbjct: 26 TRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRPANWPHDQECP 85 Query: 648 ---ARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQ 688 +F +R + L + F+ D + G I Sbjct: 86 PVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMIT 129 Score = 34.6 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 31/79 (39%), Gaps = 11/79 (13%) Query: 525 ANEEDIGDGFRRLFA--QLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 + D D RR F + G+ I+ +L+ + ++V D + M++ Sbjct: 104 IRQRDPRDELRRAFRLFDVDGKGM-ITEDDLRKVCQQVGNNIPD--------ADIQAMIE 154 Query: 583 MLDEDGSGKLGLKEFYILW 601 D +G G + EF L Sbjct: 155 EFDSNGKGGVDEDEFLRLM 173 >3IFK-A nrPDB Length = 90 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D GT+ + E+ + G +L +I AD IDF F Sbjct: 9 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 68 Query: 663 VRCLVR 668 + + R Sbjct: 69 LTMMAR 74 Score = 36.2 bits (82), Expect = 0.056, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 39/93 (41%), Gaps = 16/93 (17%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 6 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 57 Query: 587 DGSGKLGLKEFYILWTKI-------QKYQKIYR 612 DG+G + EF + + ++ ++ +R Sbjct: 58 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFR 90 >2ROB-A nrPDB Length = 70 Score = 47.7 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFV 663 ++ ++ ++ D D++G +++ E+R + G KL ++ Q+I D + ++++ FV Sbjct: 4 EELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFV 63 Query: 664 RCLVRLE 670 + ++ + Sbjct: 64 KMMMTVR 70 Score = 34.2 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 11/79 (13%) Query: 527 EEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 EE++ + F+ +F + ++ ISA EL+ ++ + K D E + M+ D Sbjct: 3 EEELKEAFK-VFDK--DQNGYISASELRHVMINLGEKLTD--------EEVEQMIKEADL 51 Query: 587 DGSGKLGLKEFYILWTKIQ 605 DG G++ +EF + ++ Sbjct: 52 DGDGQVNYEEFVKMMMTVR 70 >3K21-A nrPDB Length = 191 Score = 47.7 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 5/90 (5%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFV 663 ++K + + +D D G + +++K LE+ G KLP ++ +D ID+ F+ Sbjct: 51 VEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFI 110 Query: 664 RCLVRLEILFK-----IFKQLDPENTGTIQ 688 + + L K F+ D +N G I Sbjct: 111 AAALDRKQLSKKLIYCAFRVFDVDNDGEIT 140 Score = 44.2 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 31/155 (20%), Positives = 63/155 (40%), Gaps = 22/155 (14%) Query: 524 EANEEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 ++N+ D+ + F L + I+ +L+ L + K ++ + +++D Sbjct: 45 QSNDYDVEK-LKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLP------YNFD---LLLD 94 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQK-----IYREIDVDRSGTMNSYEMRKALEEAGFK 637 +D DGSGK+ EF ++ K +R DVD G + + E+ L K Sbjct: 95 QIDSDGSGKIDYTEFIAAALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKK 154 Query: 638 LP------CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++I +++ IDF F + Sbjct: 155 GNITQRDVNRVKRMIRDVDKNNDGKIDFHEFSEMM 189 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 506 KADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRE 565 K DY I A ++ + +++ I FR +F D EI+ EL IL K Sbjct: 103 KIDYTEF---IAAALDRKQLSKKLIYCAFR-VFD--VDNDGEITTAELAHILYNGNKKGN 156 Query: 566 DIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWT 602 + D + K M+ +D++ GK+ EF + Sbjct: 157 ITQRD---VNRVKRMIRDVDKNNDGKIDFHEFSEMMK 190 >2RO8-A nrPDB Length = 79 Score = 47.3 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D G + + E+ + G +L +I AD IDF F Sbjct: 9 ISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 68 Query: 663 VRCLVR 668 + + R Sbjct: 69 LNLMAR 74 Score = 35.8 bits (81), Expect = 0.070, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 33/77 (42%), Gaps = 9/77 (11%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 ++ F+ F+ + D I+ EL T++R + + + M++ +D Sbjct: 6 DEQISEFKEAFSLFDKDGDGCITTKELGTVMRSL--------GQNPTEAELQDMINEVDA 57 Query: 587 DGSGKLGLKEFYILWTK 603 DG+G + EF L + Sbjct: 58 DGNGTIDFPEFLNLMAR 74 Score = 30.0 bits (66), Expect = 3.9, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 26/59 (44%), Gaps = 6/59 (10%) Query: 574 IETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 I K + D+DG G + KE + + + Q + E+D D +GT++ E Sbjct: 9 ISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 67 >2KN2-A nrPDB Length = 92 Score = 47.3 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFV 663 ++ ++ ++ D D++G +++ E+R + G KL ++ Q+I D + ++++ FV Sbjct: 9 EELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFV 68 Query: 664 RCLVRLE 670 + ++ + Sbjct: 69 KMMMTVR 75 Score = 34.2 bits (77), Expect = 0.17, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 44/96 (45%), Gaps = 17/96 (17%) Query: 527 EEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 EE++ + F+ +F + ++ ISA EL+ ++ + K D E + M+ D Sbjct: 8 EEELKEAFK-VFDK--DQNGYISASELRHVMINLGEKLTD--------EEVEQMIKEADL 56 Query: 587 DGSGKLGLKEFYILWTKIQ------KYQKIYREIDV 616 DG G++ +EF + ++ + ++ R+ Sbjct: 57 DGDGQVNYEEFVKMMMTVRGGGGGNGWSRLRRKFSS 92 >3E3R-A nrPDB Length = 204 Score = 47.3 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 44/94 (46%), Gaps = 7/94 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDE-LIIDFDNF 662 IQ + +R++D D S ++++ E R+ L + G L + + ++ + +D + F Sbjct: 36 IQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEF 95 Query: 663 VRCL------VRLEILFKIFKQLDPENTGTIQLD 690 +R L R ++ F +LD G + +D Sbjct: 96 LRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVD 129 Score = 41.5 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 29/154 (18%), Positives = 58/154 (37%), Gaps = 22/154 (14%) Query: 514 DEIEANIEEIEANEEDIG----DGFRRLFAQLAGEDAE-ISAFELQTILRRVLAKREDIK 568 D ++A +E++ A G G R F QL + + + A E + L ++ + + Sbjct: 15 DAVDATMEKLRAQCLSRGASGIQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAE 74 Query: 569 SDGFSIETCKIMVDMLDEDGSGKLGLKEFYILW------TKIQKYQKIYREIDVDRSGTM 622 ++G C+ D +GSG L L+EF + + ++D G + Sbjct: 75 AEG----VCRK----WDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVV 126 Query: 623 NSYEMRKALEEAGF---KLPCQLHQVIVARFADD 653 ++R + ++ RF D+ Sbjct: 127 TVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDN 160 >5JOJ-A nrPDB Length = 97 Score = 47.3 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 38/82 (46%), Gaps = 7/82 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEA-----GFKLPCQLHQVIVARFADDELIID 658 + + ++ + ++D D +G ++ E+ + A G+++ ++ D + I Sbjct: 11 MMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRIS 70 Query: 659 FDNFVRCLVRLEI--LFKIFKQ 678 FD F++ L+ + K F++ Sbjct: 71 FDEFIKIFHGLKSTDVAKTFRK 92 Score = 31.9 bits (71), Expect = 0.94, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 34/89 (38%), Gaps = 7/89 (7%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 ++ R FA++ + IS EL + + + E + ++ D Sbjct: 8 DEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVR----EITENLMATGDL 63 Query: 587 DGSGKLGLKEFYILWTKIQ--KYQKIYRE 613 D G++ EF ++ ++ K +R+ Sbjct: 64 DQDGRISFDEFIKIFHGLKSTDVAKTFRK 92 >5Z1Q-A nrPDB Length = 95 Score = 46.9 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL-PCQLHQVIVARFADDELIIDFDNFV 663 Q+ ++ + D +++G+++ +E++ A+ GF + ++ +++ + I FD+F+ Sbjct: 27 QEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDFL 86 Query: 664 RCL 666 + Sbjct: 87 DIM 89 >4GJF-A nrPDB Length = 89 Score = 46.9 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 9/92 (9%) Query: 512 VDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDG 571 +DD +A +E++ +++ +F Q A ED IS EL ++ R+L + Sbjct: 1 MDDIYKAAVEQLTEEQKNEFKAAFDIFVQGA-EDGCISTKELGKVM-RMLGQNP------ 52 Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILWTK 603 + E + M+D +DEDGSG + EF ++ + Sbjct: 53 -TPEELQEMIDEVDEDGSGTVDFDEFLVMMVR 83 Score = 36.5 bits (83), Expect = 0.035, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 619 SGTMNSYEMRKALEEAGFK-LPCQLHQVIVARFADDELIIDFDNFVRCLVR 668 G +++ E+ K + G P +L ++I D +DFD F+ +VR Sbjct: 33 DGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVR 83 >1FW4-A nrPDB Length = 71 Score = 46.6 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFV 663 ++ ++ +R D D +G +++ E+R + G KL ++ ++I D + ++++ FV Sbjct: 6 EEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 65 Query: 664 RCL 666 + + Sbjct: 66 QMM 68 Score = 34.2 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR +F + + ISA EL+ ++ + K D E M+ D Sbjct: 4 SEEEIREAFR-VFDK--DGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 52 Query: 586 EDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 53 IDGDGQVNYEEFVQMMT 69 Score = 31.9 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 30/67 (44%), Gaps = 6/67 (8%) Query: 573 SIETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 S E + + D+DG+G + E + T + ++ ++ RE D+D G +N E Sbjct: 4 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 63 Query: 627 MRKALEE 633 + + Sbjct: 64 FVQMMTA 70 >2RO9-A nrPDB Length = 69 Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 37/64 (57%), Gaps = 1/64 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFV 663 ++ ++ +R D D++G +++ E+R + G KL ++ ++I D + I+++ FV Sbjct: 4 EELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFV 63 Query: 664 RCLV 667 + ++ Sbjct: 64 KVMM 67 Score = 33.8 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 11/76 (14%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE++ + FR +F + ++ ISA EL+ ++ + K D E M+ D Sbjct: 2 SEEELKEAFR-VFDK--DQNGFISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 50 Query: 586 EDGSGKLGLKEFYILW 601 DG G++ +EF + Sbjct: 51 VDGDGQINYEEFVKVM 66 >2B1U-A nrPDB Length = 71 Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 30/64 (46%), Gaps = 1/64 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVA-RFADDELIIDFDNF 662 ++ Q +R D D G + E+R+A+ G LP + ++ D + ++++ F Sbjct: 5 LEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEF 64 Query: 663 VRCL 666 R L Sbjct: 65 ARML 68 Score = 30.4 bits (67), Expect = 2.9, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 20/56 (35%), Gaps = 8/56 (14%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 D I+ EL+ + + E M+ D D G++ +EF + Sbjct: 20 DGHITVDELRRAMAGL--------GQPLPQEELDAMIREADVDQDGRVNYEEFARM 67 >2M5E-A nrPDB Length = 73 Score = 46.2 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Query: 609 KIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFVRCLV 667 + ++ D D +G +++ E+R + G KL ++ ++I D + I+++ FVR +V Sbjct: 12 EAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMMV 71 Score = 31.9 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 33/78 (42%), Gaps = 15/78 (19%) Query: 526 NEEDIGDGFRRLFAQLAGEDAE--ISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDM 583 +EE++ + F+ + D ISA EL+ ++ + K D + M+ Sbjct: 6 SEEELIEAFK-----VFDRDGNGLISAAELRHVMTNLGEKLTD--------DEVDEMIRE 52 Query: 584 LDEDGSGKLGLKEFYILW 601 D DG G + +EF + Sbjct: 53 ADIDGDGHINYEEFVRMM 70 >3LIJ-A nrPDB Length = 494 Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 24/159 (15%), Positives = 61/159 (38%), Gaps = 18/159 (11%) Query: 524 EANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 + ++ +F + D ++ EL + E++ F + + VD Sbjct: 338 KLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSK--LSGEEVAV--FDLPQIESEVD 393 Query: 583 ML----DEDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYEMRKALE 632 + D D +G + EF + + K + +++ D D +G ++ E+ Sbjct: 394 AILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFG 453 Query: 633 EAGFKLPCQLH-QVIVARFADDELIIDFDNFVRCLVRLE 670 L + ++I ++++ +DF+ F + + +L Sbjct: 454 LD--HLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLC 490 Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 38/206 (18%), Positives = 82/206 (39%), Gaps = 23/206 (11%) Query: 510 QTVDDEIEANIEEIEANE-EDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIK 568 Q + ++E ++ E +++ +G + L Q+ D++ Q + + + K Sbjct: 243 QEILRKVEKGKYTFDSPEWKNVSEGAKDLIKQMLQFDSQRRISAQQALEHPWIKEMCSKK 302 Query: 569 SDGFSIETCKIMVDMLDE-DGSGKLGLKEFYILWTKIQKYQK------IYREIDVDRSGT 621 G + + ++ + + S KL + +K+ ++ I+R ID + G Sbjct: 303 ESGIELPSLANAIENMRKFQNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQ 362 Query: 622 MNSYEMRKAL------EEAGFKLPC---QLHQVIVARFADDELIIDFDNFVRC------L 666 ++ E+ E A F LP ++ ++ A D ID+ FV L Sbjct: 363 LDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSL 422 Query: 667 VRLEILFKIFKQLDPENTGTIQLDLI 692 + + L F++ D + G I +D + Sbjct: 423 LSKDKLESAFQKFDQDGNGKISVDEL 448 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 27/187 (14%), Positives = 70/187 (37%), Gaps = 34/187 (18%) Query: 434 YEVPEELTGQTNIHLSKNFFLTTRARERSDTF----------INLREVLNRFKLPPGEYV 483 ++ ++L ++++ +E +D F ++ +E+++ + GE V Sbjct: 321 FQNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEV 380 Query: 484 LVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEA-NEEDIGDGFRRLFAQLA 542 V + D + + Y + + ++ +++ + F++ F Q Sbjct: 381 AVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQK-FDQ-- 437 Query: 543 GEDAEISAFELQTILRRVLAKREDIKSDGFSIE-----TCKIMVDMLDEDGSGKLGLKEF 597 + +IS EL ++ F ++ T K M+ +D + G + +EF Sbjct: 438 DGNGKISVDELASV---------------FGLDHLESKTWKEMISGIDSNNDGDVDFEEF 482 Query: 598 YILWTKI 604 + K+ Sbjct: 483 CKMIQKL 489 >2K2I-A nrPDB Length = 79 Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFV 663 ++ K ++ D D +G ++ +++ +E G L +L ++I D + + F+ Sbjct: 11 EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFL 70 Query: 664 RCL 666 R + Sbjct: 71 RIM 73 Score = 30.0 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 37/85 (43%), Gaps = 9/85 (10%) Query: 524 EANEEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 + +E+D + + F ++ +IS L+ + + + + + E + M+D Sbjct: 3 KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL--------GENLTDEELQEMID 54 Query: 583 MLDEDGSGKLGLKEFYILWTKIQKY 607 D DG G++ +EF + K Y Sbjct: 55 EADRDGDGEVSEQEFLRIMKKTSLY 79 >1W7I-B nrPDB Length = 151 Score = 45.8 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 39/89 (43%), Gaps = 9/89 (10%) Query: 585 DEDGSGKLGLKEFYILWTKI---------QKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 DE S ++ + F + + + Y + +R D + +G + E+R L G Sbjct: 58 DELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLG 117 Query: 636 FKLPCQLHQVIVARFADDELIIDFDNFVR 664 K+ + + ++A D I+++ F++ Sbjct: 118 EKMTEEEVETVLAGHEDSNGCINYEAFLK 146 Score = 31.1 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 37/96 (38%), Gaps = 12/96 (12%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-LPCQLHQVIVARFADD--ELIIDFD 660 ++++++ + D G + + + G ++ +V+ +D+ +DF+ Sbjct: 9 LEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFE 68 Query: 661 NFVRCLVRL---------EILFKIFKQLDPENTGTI 687 F+ L + E + F+ D E G + Sbjct: 69 TFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKV 104 >1GGW-A nrPDB Length = 140 Score = 45.8 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 13/96 (13%), Positives = 42/96 (43%), Gaps = 9/96 (9%) Query: 581 VDMLDEDGSGKLGLKEFYILWTKIQ---------KYQKIYREIDVDRSGTMNSYEMRKAL 631 + ++ ++ +++F + + ++ K ++ D D +G + E+R L Sbjct: 43 ITEIESTLPAEVDMEQFLQVLNRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVL 102 Query: 632 EEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLV 667 G KL + ++ + ++++ +FV+ ++ Sbjct: 103 TSLGEKLSNEEMDELLKGVPVKDGMVNYHDFVQMIL 138 Score = 30.0 bits (66), Expect = 4.1, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 36/102 (35%), Gaps = 12/102 (11%) Query: 607 YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCL 666 Y++ + D +G + + L G I + +D + F++ L Sbjct: 7 YKQAFSLFDRHGTGRIPKTSIGDLLRACG---QNPTLAEITEIESTLPAEVDMEQFLQVL 63 Query: 667 VR---------LEILFKIFKQLDPENTGTIQLDLISWLSFSV 699 R E K F+ D + TG I + + ++ S+ Sbjct: 64 NRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVLTSL 105 >3JAX-C nrPDB Length = 151 Score = 45.4 bits (106), Expect = 8e-05, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 37/89 (41%), Gaps = 9/89 (10%) Query: 585 DEDGSGKLGLKEFYILWTKI---------QKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 DE L ++F + I + Y + R D + +GT+ E+R L G Sbjct: 58 DEMNLKTLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLG 117 Query: 636 FKLPCQLHQVIVARFADDELIIDFDNFVR 664 K+ + + +VA D I+++ VR Sbjct: 118 EKMTEEEVEQLVAGHEDSNGCINYEELVR 146 >2JNX-A nrPDB Length = 134 Score = 45.0 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 57/139 (41%), Gaps = 21/139 (15%) Query: 537 LFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLK 595 LF QL A D +S E++ V +KR + + +D DG+G++ L Sbjct: 5 LFKQLDANGDGSVSYEEVKAF---VSSKRPIKNEQLLQL-----IFKAIDIDGNGEIDLA 56 Query: 596 EFYILWTKIQK---------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVI 646 EF +++ + +Y+ +D D G + E+ ++ G+ ++ I Sbjct: 57 EFTKFAAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGY---EKVVDQI 113 Query: 647 VARFADDELIIDFDNFVRC 665 + A+ + I + F+ Sbjct: 114 MKADANGDGYITLEEFLAF 132 Score = 32.7 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 37/91 (40%), Gaps = 10/91 (10%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFA-DDELIIDFDNFVRCL 666 + +++++D + G+++ E++ + QL Q+I D ID F + Sbjct: 3 EALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKFA 62 Query: 667 VRLE---------ILFKIFKQLDPENTGTIQ 688 ++ L ++K +D + G + Sbjct: 63 AAVKEQDLSDEKVGLKILYKLMDADGDGKLT 93 >5JOL-A nrPDB Length = 82 Score = 45.0 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 31/68 (45%), Gaps = 5/68 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEA-----GFKLPCQLHQVIVARFADDELIID 658 + + ++ + ++D D +G ++ E+ + A G+++ ++ D + I Sbjct: 11 MMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRIS 70 Query: 659 FDNFVRCL 666 FD F++ Sbjct: 71 FDEFIKIF 78 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 30/79 (37%), Gaps = 5/79 (6%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 ++ R FA++ + IS EL + + + E + ++ D Sbjct: 8 DEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVR----EITENLMATGDL 63 Query: 587 DGSGKLGLKEFYILWTKIQ 605 D G++ EF ++ ++ Sbjct: 64 DQDGRISFDEFIKIFHGLK 82 >1QX2-A nrPDB Length = 76 Score = 44.6 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 39/76 (51%), Gaps = 6/76 (7%) Query: 529 DIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDG 588 + G +FA G+ +IS EL+ +++ + + +++ M++ +D++G Sbjct: 5 EEIKGAFEVFAAKEGDPNQISKEELKLVMQTL---GPSLLKGMSTLDE---MIEEVDKNG 58 Query: 589 SGKLGLKEFYILWTKI 604 G++ +EF ++ KI Sbjct: 59 DGEVSFEEFLVMMKKI 74 >3I5I-C nrPDB Length = 159 Score = 44.6 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 48/130 (36%), Gaps = 22/130 (16%) Query: 522 EIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILR--------RVLAKREDIKSDG-- 571 ++ +E + LF G D ++ A ++ +LR + + K G Sbjct: 2 QLTKDEIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQHGGTKKMGEK 61 Query: 572 -FSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKA 630 + +E + + + +G EF + ++ D + G ++S E+R Sbjct: 62 AYKLEEILPIYEEMSSKDTGTAA-DEF----------MEAFKTFDREGQGLISSAEIRNV 110 Query: 631 LEEAGFKLPC 640 L+ G ++ Sbjct: 111 LKMLGERITE 120 >5H53-C nrPDB Length = 153 Score = 44.6 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 70/154 (45%), Gaps = 18/154 (11%) Query: 528 EDIGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 ++ D F+ F D++I+ ++ +LR + ++ + E K++ + +E Sbjct: 7 KEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRA-------LGTNPTNAEVKKVLGNPSNE 59 Query: 587 DGSGK-LGLKEFYILWTKI---------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 + + K + ++F + I + + + R D + +GT+ E+R L G Sbjct: 60 EMNAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE 119 Query: 637 KLPCQLHQVIVARFADDELIIDFDNFVRCLVRLE 670 K+ + + ++A D I+++ FV+ ++ ++ Sbjct: 120 KMKEEEVEALMAGQEDSNGCINYEAFVKHIMSID 153 >1ZMZ-A nrPDB Length = 98 Score = 44.2 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 33/63 (52%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK-LPCQLHQVIVARFADDELIIDFDNFV 663 Q+ ++ + D D +GT++ E++ A+ GF+ ++ ++I + ++F +F+ Sbjct: 31 QEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFL 90 Query: 664 RCL 666 + Sbjct: 91 TVM 93 Score = 39.6 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 31/78 (39%), Gaps = 13/78 (16%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSI--ETCKIMVDML 584 E+ R F + I EL+ +R + GF E K M+ + Sbjct: 27 EEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL----------GFEPKKEEIKKMISEI 76 Query: 585 DEDGSGKLGLKEFYILWT 602 D++G+GK+ +F + T Sbjct: 77 DKEGTGKMNFGDFLTVMT 94 Score = 30.8 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 28/55 (50%), Gaps = 6/55 (10%) Query: 575 ETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMN 623 + + D+ D DG+G + +KE + + ++ +K+ EID + +G MN Sbjct: 31 QEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMN 85 >6MI5-X nrPDB Length = 117 Score = 44.2 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 47/112 (41%), Gaps = 22/112 (19%) Query: 576 TCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 T K+ + D D G + LKE + + ++D D+ GT+++ E++ + EA Sbjct: 4 TTKVDIAAFDPDKDGTIDLKE------ALAAGSAAFDKLDPDKDGTLDAKELKGRVSEAD 57 Query: 636 FKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTI 687 K D++ +D + L + FK +P+N GTI Sbjct: 58 LK----------KLDPDNDGTLDKKEY------LAAVEAQFKAANPDNDGTI 93 Score = 31.5 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 36/102 (35%), Gaps = 26/102 (25%) Query: 538 FAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKE 596 F +L + D + A EL+ + K+ LD D G L KE Sbjct: 33 FDKLDPDKDGTLDAKELKGRVSEADLKK-------------------LDPDNDGTLDKKE 73 Query: 597 FYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL 638 + + + ++ + D GT+++ E+ A L Sbjct: 74 Y------LAAVEAQFKAANPDNDGTIDARELASPAGSALVNL 109 >2GGZ-A nrPDB Length = 211 Score = 44.2 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 26/141 (18%), Positives = 53/141 (37%), Gaps = 30/141 (21%) Query: 553 LQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QK 606 LQ L + K D + F D + G + EF I QK Sbjct: 48 LQG-LNQKANKHIDQVYNTF------------DTNKDGFVDFLEFIAAVNLIMQEKMEQK 94 Query: 607 YQKIYREIDVDRSGTMNSYEMR------KALEEAGFKLPCQLHQVIVARFA-DDELIIDF 659 + ++ D D +G+++ E+ +AL P + ++ + +++ + Sbjct: 95 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTL 154 Query: 660 DNFVRCLVR----LEILFKIF 676 + F+ + + LEI++K F Sbjct: 155 EEFINGMAKDQDLLEIVYKSF 175 >3L19-A nrPDB Length = 214 Score = 44.2 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 24/159 (15%), Positives = 61/159 (38%), Gaps = 18/159 (11%) Query: 524 EANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVD 582 + ++ +F + D ++ EL + E++ F + + VD Sbjct: 55 KLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSK--LSGEEVAV--FDLPQIESEVD 110 Query: 583 ML----DEDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYEMRKALE 632 + D D +G + EF + + K + +++ D D +G ++ E+ Sbjct: 111 AILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFG 170 Query: 633 EAGFKLPCQLH-QVIVARFADDELIIDFDNFVRCLVRLE 670 L + ++I ++++ +DF+ F + + +L Sbjct: 171 LD--HLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLC 207 Score = 36.9 bits (84), Expect = 0.029, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 15/103 (14%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKAL------EEAGFKLPC---QLHQVIVARFADDEL 655 ++ I+R ID + G ++ E+ E A F LP ++ ++ A D Sbjct: 63 KELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAADFDRNG 122 Query: 656 IIDFDNFVRC------LVRLEILFKIFKQLDPENTGTIQLDLI 692 ID+ FV L+ + L F++ D + G I +D + Sbjct: 123 YIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDEL 165 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 33/74 (44%), Gaps = 4/74 (5%) Query: 573 SIETCKIMVDMLDEDGSGKLGLKEFYIL----WTKIQKYQKIYREIDVDRSGTMNSYEMR 628 S + + D+DG+GK+ + E + + + ++++ ID + G ++ E Sbjct: 141 SKDKLESAFQKFDQDGNGKISVDELASVFGLDHLESKTWKEMISGIDSNNDGDVDFEEFC 200 Query: 629 KALEEAGFKLPCQL 642 K +++ QL Sbjct: 201 KMIQKLCSNNEPQL 214 Score = 29.2 bits (64), Expect = 5.8, Method: Composition-based stats. Identities = 27/182 (14%), Positives = 69/182 (37%), Gaps = 24/182 (13%) Query: 434 YEVPEELTGQTNIHLSKNFFLTTRARERSDTF----------INLREVLNRFKLPPGEYV 483 ++ ++L ++++ +E +D F ++ +E+++ + GE V Sbjct: 38 FQNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEV 97 Query: 484 LVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEA-NEEDIGDGFRRLFAQLA 542 V + D + + Y + + ++ +++ + F++ F Q Sbjct: 98 AVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQK-FDQ-- 154 Query: 543 GEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWT 602 + +IS EL ++ D +T K M+ +D + G + +EF + Sbjct: 155 DGNGKISVDELASVFGL----------DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQ 204 Query: 603 KI 604 K+ Sbjct: 205 KL 206 >2G9B-A nrPDB Length = 263 Score = 44.2 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 43/109 (39%), Gaps = 14/109 (12%) Query: 548 ISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILW----TK 603 I EL+ L+ +L K D E +M+ + D + GKL L E L Sbjct: 120 IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 179 Query: 604 IQKYQKI----------YREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 + K+Q I + D D +G ++ E+ L++ K +L Sbjct: 180 LLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQEL 228 Score = 39.6 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 32/188 (17%), Positives = 69/188 (36%), Gaps = 40/188 (21%) Query: 546 AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILW---- 601 + ELQ +++ +L R+ S E K VD + GK+G+ E + Sbjct: 31 GYLEGKELQNLIQELLQARKK-AGLELSPE-MKTFVDQYGQRDDGKIGIVELAHVLPTEE 88 Query: 602 -----------TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARF 650 +++ K +R+ D D SG + + E++ L++ K + +A + Sbjct: 89 NFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEY 148 Query: 651 ---------ADDELIIDFDNFVRCL------------VRLEI--LFKIFKQLDPENTGTI 687 ++++ ++ R L +++ K F+ D + G I Sbjct: 149 TDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 208 Query: 688 QLDLISWL 695 + + L Sbjct: 209 DENELDAL 216 Score = 34.6 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 46/107 (42%), Gaps = 22/107 (20%) Query: 609 KIYREIDVDRSGTMNSYEMR-------KALEEAGFKLPCQLHQVIVARFADDELIID--- 658 +I+ D D SG + E++ +A ++AG +L ++ + D+ I Sbjct: 20 EIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE 79 Query: 659 -------FDNFV---RC--LVRLEILFKIFKQLDPENTGTIQLDLIS 693 +NF+ RC L E K +++ D +++G I+ + + Sbjct: 80 LAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 126 >2K7C-A nrPDB Length = 72 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 38/67 (56%), Gaps = 2/67 (2%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKAL-EEAGFKLPCQLHQVIVARFA-DDELIIDFDN 661 +++ + +RE D + G +++ E+R+A+ + G ++ + + I+ + + +DF+ Sbjct: 6 VKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEE 65 Query: 662 FVRCLVR 668 FVR + R Sbjct: 66 FVRMMSR 72 Score = 35.0 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 28/59 (47%), Gaps = 7/59 (11%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTK 603 D EIS EL+ +R++L + ++ +D +G G++ +EF + ++ Sbjct: 21 DGEISTSELREAMRKLL-------GHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR 72 >2KZ2-A nrPDB Length = 94 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFV 663 ++ ++ +R D D +G +++ E+R + G KL ++ ++I D + ++++ FV Sbjct: 29 EEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 88 Query: 664 RCL 666 + + Sbjct: 89 QMM 91 Score = 33.8 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 11/77 (14%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I + FR + + ISA EL+ ++ + K D E M+ D Sbjct: 27 SEEEIREAFR---VEDKDGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 75 Query: 586 EDGSGKLGLKEFYILWT 602 DG G++ +EF + T Sbjct: 76 IDGDGQVNYEEFVQMMT 92 Score = 30.0 bits (66), Expect = 3.9, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 30/67 (44%), Gaps = 6/67 (8%) Query: 573 SIETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYE 626 S E + + D+DG+G + E + T + ++ ++ RE D+D G +N E Sbjct: 27 SEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 86 Query: 627 MRKALEE 633 + + Sbjct: 87 FVQMMTA 93 >2KSZ-A nrPDB Length = 76 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNF 662 I +++ + D D G + E+ + +L +I AD I+FD F Sbjct: 9 IVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEF 68 Query: 663 VRCLVR 668 + + + Sbjct: 69 LSLMAK 74 Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 10/80 (12%) Query: 525 ANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDM 583 +EE I D F+ F + D I+ EL T++R + + E + M+ Sbjct: 4 LSEEQIVD-FKEAFGLFDKDGDGCITVEELATVIRSLDQNPTE--------EELQDMISE 54 Query: 584 LDEDGSGKLGLKEFYILWTK 603 +D DG+G + EF L K Sbjct: 55 VDADGNGTIEFDEFLSLMAK 74 >1JFJ-A nrPDB Length = 134 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 41/93 (44%), Gaps = 12/93 (12%) Query: 584 LDEDGSGKLGLKEFYILWTKIQ---------KYQKIYREIDVDRSGTMNSYEMRKALEEA 634 +D DG+G++ EF + IQ + +Y+ +DVD G + E+ ++ Sbjct: 45 IDADGNGEIDQNEFAKFYGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKH 104 Query: 635 GFKLPCQLHQVIVARFADDELIIDFDNFVRCLV 667 G ++ + ++ A+ + I + F+ + Sbjct: 105 GI---EKVAEQVMKADANGDGYITLEEFLEFSL 134 Score = 36.2 bits (82), Expect = 0.058, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Query: 514 DEIEANIEEIEANEEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGF 572 +E++A + + A + + +F + + EI E + + +D+ D Sbjct: 20 EEVKAFVSKKRAIKNEQLLQL--IFKSIDADGNGEIDQNEFAKFYGSI--QGQDLSDDKI 75 Query: 573 SIETCKIMVDMLDEDGSGKLGLKEFYILWTK--IQKYQKIYREIDVDRSGTMNSYE 626 + K++ ++D DG GKL +E + K I+K + + D + G + E Sbjct: 76 GL---KVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKADANGDGYITLEE 128 Score = 32.7 bits (73), Expect = 0.55, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 40/91 (43%), Gaps = 10/91 (10%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVAR-FADDELIIDFDNFVRCL 666 + +++EIDV+ G ++ E++ + + QL Q+I AD ID + F + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 667 VRLE---------ILFKIFKQLDPENTGTIQ 688 ++ L ++K +D + G + Sbjct: 63 GSIQGQDLSDDKIGLKVLYKLMDVDGDGKLT 93 >2K7B-A nrPDB Length = 76 Score = 43.9 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I++ ++ +RE D D+ G +N ++ + G+ +L ++ + +DFD+F Sbjct: 9 IEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDF 68 Query: 663 VRCL 666 V + Sbjct: 69 VELM 72 >5H53-B nrPDB Length = 146 Score = 43.5 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 48/105 (45%), Gaps = 11/105 (10%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG-FKLPCQLHQVIVARFADDELIIDFD 660 T+IQ++++ + ID +R G ++ ++R G + + ++ + I+F Sbjct: 2 TQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKEAS---GPINFT 58 Query: 661 NFVRCL-VRL------EILFKIFKQLDPENTGTIQLDLISWLSFS 698 F+ +L +++ FK LDPE GTI+ + L + Sbjct: 59 VFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELLIT 103 >2ZFD-A nrPDB Length = 226 Score = 43.1 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 38/193 (19%), Positives = 73/193 (37%), Gaps = 41/193 (21%) Query: 513 DDEIEANIEEIEANE-EDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDG 571 D E+ A +E E + + F+++ + + +D I+ E Q L + K Sbjct: 32 DPELLARDTVFSVSEIEALYELFKKISSAVI-DDGLINKEEFQLALFKTNKKESLFADRV 90 Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNS 624 F D+ D +G LG +EF + K ++ D+ + G + Sbjct: 91 F---------DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIER 141 Query: 625 YEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENT 684 E++ Q++VA A+ + + D + +I+ K F++ D ++ Sbjct: 142 QEVK---------------QMVVATLAESGMNLK-DTVIE-----DIIDKTFEEADTKHD 180 Query: 685 GTIQLDLISWLSF 697 G I D W S Sbjct: 181 GKI--DKEEWRSL 191 >5MWC-D nrPDB Length = 311 Score = 42.7 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 25/61 (40%), Gaps = 1/61 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIV-ARFADDELIIDFDNFV 663 ++ + +R D D G ++ E + G +L + I D IDFD F+ Sbjct: 151 EELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFL 210 Query: 664 R 664 + Sbjct: 211 K 211 Score = 30.4 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 28/57 (49%), Gaps = 8/57 (14%) Query: 584 LDEDGSGKLGLKEFYILWTKIQKYQ-------KIYREIDVDRSGTMNSYEMRKALEE 633 D+DG G + +EF + ++ Q +I+ + D D++G ++ E K +E Sbjct: 160 FDKDGDGFIDREEFGGI-IRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFLKMVEN 215 >1H4B-A nrPDB Length = 84 Score = 42.7 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 28/55 (50%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNF 662 ++I++ D + G +++ E+ +AL+ G P ++ ++ D + I F F Sbjct: 12 ERIFKRFDANGDGKISAAELGEALKTLGSITPDEVKHMMAEIDTDGDGFISFQEF 66 Score = 36.2 bits (82), Expect = 0.049, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 33/79 (41%), Gaps = 12/79 (15%) Query: 521 EEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIM 580 ++ ++ + F+R A D +ISA EL L+ + + D K M Sbjct: 2 DDHPQDKAERERIFKRF---DANGDGKISAAELGEALKTLGSITPD---------EVKHM 49 Query: 581 VDMLDEDGSGKLGLKEFYI 599 + +D DG G + +EF Sbjct: 50 MAEIDTDGDGFISFQEFTD 68 >3MSE-B nrPDB Length = 180 Score = 42.3 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 44/97 (45%), Gaps = 6/97 (6%) Query: 596 EFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDEL 655 E ++ I+ +++ ++D + +G+++ E+ L G K +++++ A +D Sbjct: 30 ELSVINNHIKYINELFYKLDTNHNGSLSHREIYTVLASVGIK-KWDINRILQALDINDRG 88 Query: 656 IIDFDNFVRCLVRLEI-----LFKIFKQLDPENTGTI 687 I + F+ R + L F ++D + G I Sbjct: 89 NITYTEFMAGCYRWKNIESTFLKAAFNKIDKDEDGYI 125 >1S6J-A nrPDB Length = 87 Score = 42.3 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 8/84 (9%) Query: 585 DEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLH 643 D+ + +L +E L +++++ ID D SGT+ E++ L+ G +L ++ Sbjct: 10 DKHMAERLSEEEIGGL-------KELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIK 62 Query: 644 QVIVARFADDELIIDFDNFVRCLV 667 ++ A D ID+ F+ V Sbjct: 63 DLMDAADIDKSGTIDYGEFIAATV 86 Score = 35.4 bits (80), Expect = 0.095, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 26/59 (44%), Gaps = 6/59 (10%) Query: 578 KIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEMRKA 630 K + M+D D SG + E ++ + + + D+D+SGT++ E A Sbjct: 26 KELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEFIAA 84 Score = 30.4 bits (67), Expect = 3.2, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 10/74 (13%) Query: 525 ANEEDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDM 583 +EE+IG G + LF + ++ I+ EL+ L+RV K ++D Sbjct: 17 LSEEEIG-GLKELFKMIDTDNSGTITFDELKDGLKRV--------GSELMESEIKDLMDA 67 Query: 584 LDEDGSGKLGLKEF 597 D D SG + EF Sbjct: 68 ADIDKSGTIDYGEF 81 >4D1E-A nrPDB Length = 876 Score = 42.3 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 10/73 (13%), Positives = 30/73 (41%), Gaps = 1/73 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 + +++ + D ++G M+ + R L G+ L + +++ + + + F +F Sbjct: 737 MNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTVTFQSF 796 Query: 663 VRCLVRLEILFKI 675 + + R Sbjct: 797 IDFMTRETADTDT 809 >2BL0-B nrPDB Length = 145 Score = 42.3 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 34/89 (38%), Gaps = 6/89 (6%) Query: 606 KYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIID-FDNFVR 664 + Q+ ++ D D G ++ E+ AL G I + E + F R Sbjct: 6 QIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTIKGQLNAKEFDLATFKTVYR 65 Query: 665 CLVRL-----EILFKIFKQLDPENTGTIQ 688 ++ + + F+ LD E GTIQ Sbjct: 66 KPIKTPTEQSKEMLDAFRALDKEGNGTIQ 94 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 33/142 (23%), Positives = 59/142 (41%), Gaps = 28/142 (19%) Query: 549 SAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGS--------GKLGLKEFYIL 600 SA ++Q ++ K D K SIE + L ++ + G+L KEF L Sbjct: 3 SADQIQECF-QIFDKDNDGKV---SIEELGSALRSLGKNPTNAELNTIKGQLNAKEF-DL 57 Query: 601 WTKIQKYQK--------------IYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVI 646 T Y+K +R +D + +GT+ E+R+ L G L + + Sbjct: 58 ATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSSEVEEL 117 Query: 647 VARFA-DDELIIDFDNFVRCLV 667 + + + I++++FV LV Sbjct: 118 MKEVSVSGDGAINYESFVDMLV 139 >1UHN-A nrPDB Length = 189 Score = 41.9 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 38/193 (19%), Positives = 73/193 (37%), Gaps = 41/193 (21%) Query: 513 DDEIEANIEEIEANE-EDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDG 571 D E+ A +E E + + F+++ + + +D I+ E Q L + K Sbjct: 1 DPELLARDTVFSVSEIEALYELFKKISSAVI-DDGLINKEEFQLALFKTNKKESLFADRV 59 Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNS 624 F D+ D +G LG +EF + K ++ D+ + G + Sbjct: 60 F---------DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIER 110 Query: 625 YEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENT 684 E++ Q++VA A+ + + D + +I+ K F++ D ++ Sbjct: 111 QEVK---------------QMVVATLAESGMNLK-DTVIE-----DIIDKTFEEADTKHD 149 Query: 685 GTIQLDLISWLSF 697 G I D W S Sbjct: 150 GKI--DKEEWRSL 160 >2QFE-A nrPDB Length = 148 Score = 41.9 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 38/144 (26%), Positives = 59/144 (40%), Gaps = 31/144 (21%) Query: 360 KMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQ 419 +++G W G +AGGC N+ T NP Y +E+ LI+ RQ Sbjct: 26 RINGKWS-GQSAGGCGNFQETHKNNPIYQFHIEKTGP-------------LLIELRGPRQ 71 Query: 420 RKMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPP 479 +++GF + V G H FL + + F L E+ N +P Sbjct: 72 -------YSVGFEVVTV--STLGDPGPH----GFLRKSSGDYRCGFCYL-ELEN---IPS 114 Query: 480 GEYVLVPSTFEPHKNGDFCIRVFS 503 G + ++PSTF P + G F + S Sbjct: 115 GIFNIIPSTFLPKQEGPFFLDFNS 138 >3JBH-C nrPDB Length = 156 Score = 41.5 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 31/139 (22%), Positives = 62/139 (44%), Gaps = 31/139 (22%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDML------DEDGSGKLGLKEFY 598 + +I A +L +LR S++ CK + M+ D+ G KL L+EF Sbjct: 24 EGKIDARDLGDLLR--------------SLD-CKPTLAMVKKNGGSDKRGEKKLTLEEFL 68 Query: 599 ILWTKIQK---------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVAR 649 ++++I+K + + + D +GTM + E+ L G +L + I+ Sbjct: 69 PIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTDIECEEIMRV 128 Query: 650 -FADDELIIDFDNFVRCLV 667 DD+ + ++ FV+ ++ Sbjct: 129 CDEDDDGFLKYEPFVKTII 147 >1O1A-B nrPDB Length = 145 Score = 41.5 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 46/102 (45%), Gaps = 11/102 (10%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG-FKLPCQLHQVIVARFADDELIIDFD 660 T+I+ +++ + ID + G ++ ++R+ G + + ++ + I+F Sbjct: 4 TEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEAS---GPINFT 60 Query: 661 NFVRCL-VRL------EILFKIFKQLDPENTGTIQLDLISWL 695 F+ +L +++ FK LDP+ G+I+ + L Sbjct: 61 VFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEEL 102 Score = 31.1 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 55/145 (37%), Gaps = 21/145 (14%) Query: 526 NEEDIGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDML 584 +E +I D F+ F + D I +L+ R ++K+ E M+ Sbjct: 2 DETEIED-FKEAFTVIDQNADGIIDKDDLRETF--AAMGRLNVKN-----EELDAMI--- 50 Query: 585 DEDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 ++ SG + F ++ + K ++ +D D G++ + + L G + Sbjct: 51 -KEASGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGR 109 Query: 638 LPCQLHQVIVARFADDE-LIIDFDN 661 + + + A F D +D+ N Sbjct: 110 FTPEEIKNMWAAFPPDVAGNVDYKN 134 >1I84-U nrPDB Length = 166 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 46/102 (45%), Gaps = 11/102 (10%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG-FKLPCQLHQVIVARFADDELIIDFD 660 T+I+ +++ + ID + G ++ ++R+ G + + ++ + I+F Sbjct: 22 TEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEAS---GPINFT 78 Query: 661 NFVRCL-VRL------EILFKIFKQLDPENTGTIQLDLISWL 695 F+ +L +++ FK LDP+ G+I+ + L Sbjct: 79 VFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEEL 120 Score = 31.1 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 55/145 (37%), Gaps = 21/145 (14%) Query: 526 NEEDIGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDML 584 +E +I D F+ F + D I +L+ R ++K+ E M+ Sbjct: 20 DETEIED-FKEAFTVIDQNADGIIDKDDLRETF--AAMGRLNVKN-----EELDAMI--- 68 Query: 585 DEDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFK 637 ++ SG + F ++ + K ++ +D D G++ + + L G + Sbjct: 69 -KEASGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGR 127 Query: 638 LPCQLHQVIVARFADDE-LIIDFDN 661 + + + A F D +D+ N Sbjct: 128 FTPEEIKNMWAAFPPDVAGNVDYKN 152 >5TBY-C nrPDB Length = 195 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 34/82 (41%), Gaps = 9/82 (10%) Query: 592 LGLKEFYILWTKI---------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 + + F + I + + + R D + +GT+ E+R L G +L Sbjct: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDE 168 Query: 643 HQVIVARFADDELIIDFDNFVR 664 + ++A D I+++ FV+ Sbjct: 169 VEKLMAGQEDSNGCINYEAFVK 190 >6FSA-D nrPDB Length = 199 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 34/86 (39%), Gaps = 9/86 (10%) Query: 588 GSGKLGLKEFYILWTKI---------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL 638 S + F + I + + + R D + +GT+ E+R L G KL Sbjct: 109 NSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKL 168 Query: 639 PCQLHQVIVARFADDELIIDFDNFVR 664 + ++A D I+++ FV+ Sbjct: 169 TEDEVEKLMAGQEDSNGCINYEAFVK 194 >2W4G-C nrPDB Length = 145 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 38/88 (43%), Gaps = 9/88 (10%) Query: 591 KLGLKEFYILWTK---------IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQ 641 K+ +EF + + + + R D + +GT+ E+R L G K+ + Sbjct: 58 KITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEE 117 Query: 642 LHQVIVARFADDELIIDFDNFVRCLVRL 669 + ++ D I+++ FV+ ++ + Sbjct: 118 EVEELMKGQEDSNGCINYEAFVKHIMSV 145 >5T7C-A nrPDB Length = 193 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 26/136 (19%), Positives = 47/136 (34%), Gaps = 28/136 (20%) Query: 589 SGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNSYEMRKALEEAGF-KLPC 640 +G L + EF ++ Y + ++R D + GT++ E AL KL Sbjct: 40 TGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQ 99 Query: 641 QLHQVIVARFADDELIIDFDNFVRCLVRLEILF------------------KIFKQLDPE 682 +L D I + + + + KIF+Q+D Sbjct: 100 KLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTN 159 Query: 683 NTGTIQLDLISWLSFS 698 N G +L L ++ + Sbjct: 160 NDG--KLSLEEFIRGA 173 >1TRF-A nrPDB Length = 76 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVAR-FADDELIIDFDNF 662 I +++ + D D G +++ E+ + G + I+ D IDF+ F Sbjct: 8 IAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEF 67 Query: 663 VRCLVR 668 + +VR Sbjct: 68 LVMMVR 73 Score = 37.7 bits (86), Expect = 0.017, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 9/77 (11%) Query: 528 EDIGDGFRRLFAQLAGEDA-EISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E++ F+ F + +IS EL T++ R+L + + E +++ +DE Sbjct: 5 EEMIAEFKAAFDMFDADGGGDISTKELGTVM-RMLGQNP-------TKEELDAIIEEVDE 56 Query: 587 DGSGKLGLKEFYILWTK 603 DGSG + +EF ++ + Sbjct: 57 DGSGTIDFEEFLVMMVR 73 >1TNP-A nrPDB Length = 90 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 34/88 (38%), Gaps = 6/88 (6%) Query: 582 DMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQ 641 M D+ + L E I +++ + D D G +++ E+ + G + Sbjct: 2 SMTDQQAEARAFLSE-----EMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKE 56 Query: 642 LHQVIVAR-FADDELIIDFDNFVRCLVR 668 I+ D IDF+ F+ +VR Sbjct: 57 ELDAIIEEVDEDGSGTIDFEEFLVMMVR 84 Score = 37.3 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 9/77 (11%) Query: 528 EDIGDGFRRLFAQLAGEDA-EISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E++ F+ F + +IS EL T++ R+L + + E +++ +DE Sbjct: 16 EEMIAEFKAAFDMFDADGGGDISTKELGTVM-RMLGQNP-------TKEELDAIIEEVDE 67 Query: 587 DGSGKLGLKEFYILWTK 603 DGSG + +EF ++ + Sbjct: 68 DGSGTIDFEEFLVMMVR 84 >5M6C-E nrPDB Length = 193 Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 48/136 (35%), Gaps = 28/136 (20%) Query: 589 SGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNSYEMRKALEEAGF-KLPC 640 +G L + EF ++ Y + ++R D + GT++ E AL +L Sbjct: 40 TGILNVDEFKKIYANFFPYGDASKFAEHVFRNFDTNSDGTIDFREFIIALSVTSRGRLEQ 99 Query: 641 QLHQVIVARFADDELIIDFDNFVRCLVRLEILF------------------KIFKQLDPE 682 +L D I + + + + + KIF+Q+D Sbjct: 100 KLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159 Query: 683 NTGTIQLDLISWLSFS 698 N G +L L ++ + Sbjct: 160 NDG--KLSLEEFIRGA 173 Score = 30.0 bits (66), Expect = 4.1, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 27/70 (38%), Gaps = 18/70 (25%) Query: 582 DMLDEDGSGKLGLKEFYILWTKIQKY------------------QKIYREIDVDRSGTMN 623 M D DG+G + +E + I K +KI+R++D + G ++ Sbjct: 106 SMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLS 165 Query: 624 SYEMRKALEE 633 E + + Sbjct: 166 LEEFIRGAKS 175 >2Q4U-A nrPDB Length = 272 Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 38/189 (20%), Positives = 75/189 (39%), Gaps = 33/189 (17%) Query: 528 EDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDG-FSIETCKIMVDMLDE 586 +++ D FR + +L +D +I+ +Q I ++ D DG IE M+ L + Sbjct: 31 KELDDFFRHMLKKLQPKD-KITDERVQQI-KKSFMSAYDATFDGRLQIEELANMI--LPQ 86 Query: 587 DGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF---------K 637 + + L + L + ++ KI+R+ D D SG +++ E++ L++ K Sbjct: 87 EENFLLIFRREAPLDNSV-EFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNK 145 Query: 638 LPCQLHQVIVARFADDELIIDFDNFVRCLV------------------RLEILFKIFKQL 679 L ++ + + +D ++ R L R KIF Sbjct: 146 LDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHY 205 Query: 680 DPENTGTIQ 688 D TG ++ Sbjct: 206 DVSRTGALE 214 Score = 37.3 bits (85), Expect = 0.021, Method: Composition-based stats. Identities = 27/152 (17%), Positives = 57/152 (37%), Gaps = 32/152 (21%) Query: 542 AGEDAEISAFELQTILRRVLAKREDIKSDGFSIET-CKIMVDMLDEDGSGKLGLKEFYIL 600 A ISA EL+ L+ + + + K ++ M+ + D++ G+L L + + Sbjct: 115 ADSSGYISAAELKNFLKDLFLQHKK-KIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARI 173 Query: 601 WT------------------KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 + + ++KI+ DV R+G + E+ +++ Sbjct: 174 LALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVKDM-------- 225 Query: 643 HQVIVARFADDELIIDFDNFVRCLVRLEILFK 674 + + R + D D F CL+ + K Sbjct: 226 --MELVRPSISGG--DLDKFRECLLTHCDMNK 253 >1JC2-A nrPDB Length = 76 Score = 40.0 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVA-RFADDELIIDFDNFV 663 ++ +R D + G ++ E+ + L G + + + ++ +++ IDFD F+ Sbjct: 10 EELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFDEFL 69 Query: 664 RCL 666 + + Sbjct: 70 KMM 72 Score = 31.5 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 34/86 (39%), Gaps = 10/86 (11%) Query: 520 IEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKI 579 +E+ + E+ R+F + A D I EL ILR + E + Sbjct: 1 MEDAKGKSEEELANCFRIFDKNA--DGFIDIEELGEILRA--------TGEHVIEEDIED 50 Query: 580 MVDMLDEDGSGKLGLKEFYILWTKIQ 605 ++ D++ G++ EF + +Q Sbjct: 51 LMKDSDKNNDGRIDFDEFLKMMEGVQ 76 >2JUL-A nrPDB Length = 256 Score = 39.6 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 27/197 (13%), Positives = 72/197 (36%), Gaps = 33/197 (16%) Query: 503 SEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGE--DAEISAFELQTILRRV 560 S+ + + TV + E +++++A + + L+ E + + I + Sbjct: 63 SDSELELSTVRHQPEG-LDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQF 121 Query: 561 LAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREI 614 + + F + + D DG+G + ++F + + + +K + + Sbjct: 122 FPQGDATTYAHF-------LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLY 174 Query: 615 DVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFK 674 D+++ G + EM ++ + + I+ A LE + + Sbjct: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYP-ILREDAP----------------LEHVER 217 Query: 675 IFKQLDPENTGTIQLDL 691 F+++D G + +D Sbjct: 218 FFQKMDRNQDGVVTIDE 234 >1F55-A nrPDB Length = 77 Score = 39.6 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 31/66 (46%), Gaps = 1/66 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 I ++++ + D D +G+++S E+ + G +++ ++ D I+F F Sbjct: 9 IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEF 68 Query: 663 VRCLVR 668 + + R Sbjct: 69 LALMSR 74 Score = 31.5 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 34/77 (44%), Gaps = 9/77 (11%) Query: 528 EDIGDGFRRLFAQLAGED-AEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 E+ F+ FA ++ IS+ EL T++R + + +++ +D Sbjct: 6 EEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSE--------AEVNDLMNEIDV 57 Query: 587 DGSGKLGLKEFYILWTK 603 DG+ ++ EF L ++ Sbjct: 58 DGNHQIEFSEFLALMSR 74 >5TBY-E nrPDB Length = 166 Score = 39.6 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 47/101 (46%), Gaps = 15/101 (14%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL---PCQLHQVIVARFADDELIID 658 T+IQ++++ + +D +R G ++ ++R G ++ ++ ++I + I+ Sbjct: 24 TQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALG-RVNVKNEEIDEMI----KEAPGPIN 78 Query: 659 FDNFVRCL-VRL------EILFKIFKQLDPENTGTIQLDLI 692 F F+ +L E + FK DPE G ++ D + Sbjct: 79 FTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYV 119 Score = 34.2 bits (77), Expect = 0.17, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 53/158 (33%), Gaps = 26/158 (16%) Query: 518 ANIEEIEANEEDIGDGFRRLFAQL-AGEDAEISAFELQTI---LRRVLAKREDIKSDGFS 573 AN E+ F+ F + D I +L+ L RV K E+ Sbjct: 13 ANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEE------- 65 Query: 574 IETCKIMVDMLDEDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYE 626 +D + ++ G + F ++ + K ++ D + G + + Sbjct: 66 -------IDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADY 118 Query: 627 MRKALEEAGFKLPCQLHQVIVARF-ADDELIIDFDNFV 663 +R+ L + + + A F D +D+ N V Sbjct: 119 VREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLV 156 >2E30-A nrPDB Length = 195 Score = 39.6 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 34/183 (18%), Positives = 67/183 (36%), Gaps = 20/183 (10%) Query: 506 KADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRE 565 +A D+E+E +E + I + R + GE+ +S + Q I + Sbjct: 4 RASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLG 63 Query: 566 DIKSDGFSIET---------CKIMVD---MLDEDGSGKLGLKEFYILWTKIQKYQKIYRE 613 D + F E + + + D + S + E L ++ K +R Sbjct: 64 DRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPE--PLNSRSNKLHFAFRL 121 Query: 614 IDVDRSGTMNSYEMRKALEEA-GFKLPCQLHQVIVAR-----FADDELIIDFDNFVRCLV 667 D+D+ ++ E+ + L G + + I R D + I F FV+ L Sbjct: 122 YDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLE 181 Query: 668 RLE 670 +++ Sbjct: 182 KVD 184 >2BEC-A nrPDB Length = 202 Score = 39.2 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 35/77 (45%), Gaps = 6/77 (7%) Query: 600 LWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA-GFKLPCQLHQVIVAR-----FADD 653 L ++ K ++ D+DR G ++ +EM + L G ++ + + I R D Sbjct: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG 168 Query: 654 ELIIDFDNFVRCLVRLE 670 + + F F + L +++ Sbjct: 169 DGAVSFVEFTKSLEKMD 185 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 17/113 (15%), Positives = 36/113 (31%), Gaps = 34/113 (30%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRK----ALEEAGFKLPCQLHQVIVARFADDELII 657 + + +R +D ++ G ++ ++++ A+ G ++ F D + Sbjct: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF-------FPDGSQRV 78 Query: 658 DFDNFVRCLVRLEILFK-----------------------IFKQLDPENTGTI 687 DF FVR L + F+ D + G I Sbjct: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 >1BJF-A nrPDB Length = 193 Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 26/136 (19%), Positives = 47/136 (34%), Gaps = 28/136 (20%) Query: 589 SGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNSYEMRKALEEAGF-KLPC 640 SG L ++EF ++ Y + ++R D + GT++ E AL KL Sbjct: 40 SGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQ 99 Query: 641 QLHQVIVARFADDELIIDFDNFVRCLVRLEILF------------------KIFKQLDPE 682 +L D I + + + + KIF+Q+D Sbjct: 100 KLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159 Query: 683 NTGTIQLDLISWLSFS 698 G +L L ++ + Sbjct: 160 RDG--KLSLEEFIRGA 173 >3TZ1-A nrPDB Length = 74 Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNFV 663 ++ ++ +R +D ++ G + +R L+ G +L ++ +I D +D++ F Sbjct: 7 RELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEFK 66 Query: 664 RCLVRLEI 671 ++ + Sbjct: 67 CLMMSSDA 74 Score = 37.7 bits (86), Expect = 0.017, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 11/78 (14%) Query: 524 EANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDM 583 + +E ++ + FR L + + I L+ IL+ + D + + + M+ Sbjct: 3 DLDERELKEAFRVLDKE---KKGVIKVDVLRWILKSL--------GDELTEDEIENMIAE 51 Query: 584 LDEDGSGKLGLKEFYILW 601 D DGSG + +EF L Sbjct: 52 TDTDGSGTVDYEEFKCLM 69 >5I2L-A nrPDB Length = 120 Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 9/74 (12%) Query: 594 LKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLH----QVIVAR 649 KEF +I+ +K++++ D R G ++ E++ +E+ G Q H +I Sbjct: 22 FKEFSR--KQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLG---APQTHLGLKNMIKEV 76 Query: 650 FADDELIIDFDNFV 663 D + + F F+ Sbjct: 77 DEDFDSKLSFREFL 90 Score = 33.1 bits (74), Expect = 0.49, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 10/84 (11%) Query: 521 EEIEANEEDIGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKI 579 E E + + I D ++F Q AG D I EL+ ++ ++ A + + K Sbjct: 21 EFKEFSRKQIKD-MEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLG--------LKN 71 Query: 580 MVDMLDEDGSGKLGLKEFYILWTK 603 M+ +DED KL +EF +++ K Sbjct: 72 MIKEVDEDFDSKLSFREFLLIFRK 95 >1SJJ-A nrPDB Length = 863 Score = 38.5 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 9/73 (12%), Positives = 29/73 (39%), Gaps = 1/73 (1%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 + +++ + D ++G M+ + R L G+ + + +++ + ++ F F Sbjct: 724 MNEFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPNRMGVVTFQAF 783 Query: 663 VRCLVRLEILFKI 675 + + R Sbjct: 784 IDFMSRETADTDT 796 >2PMY-A nrPDB Length = 91 Score = 38.5 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Query: 569 SDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQ----KYQKIYREIDVDRSGTMNS 624 DG + + + D + SG+L +EF L T+++ + +++ +D DR G + Sbjct: 21 GDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDGAITF 80 Query: 625 YEMRKALEEA 634 E + + Sbjct: 81 QEFARGFLGS 90 >2M8U-A nrPDB Length = 77 Score = 38.1 bits (87), Expect = 0.013, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 28/59 (47%), Gaps = 1/59 (1%) Query: 609 KIYREIDVDRSGTMNSYEMRKALEEAGFKLP-CQLHQVIVARFADDELIIDFDNFVRCL 666 + ++ D D +G + +RK L E G +P ++ ++I + + ++ FV L Sbjct: 15 EAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSGYVQYETFVGML 73 >2M97-A nrPDB Length = 69 Score = 38.1 bits (87), Expect = 0.013, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 27/63 (42%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIV-ARFADDELIIDFDNFV 663 ++ + +R D D +G ++ E + G +L + I D IDFD F+ Sbjct: 3 EELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFL 62 Query: 664 RCL 666 + + Sbjct: 63 KMM 65 Score = 30.0 bits (66), Expect = 3.7, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 28/57 (49%), Gaps = 6/57 (10%) Query: 583 MLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEMRKALEE 633 + D+DG+G + +EF + + +I+ + D D++G ++ E K +E Sbjct: 11 IFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFLKMMEN 67 >1OZS-A nrPDB Length = 73 Score = 38.1 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVAR-FADDELIIDFDNFV 663 ++ ++R D + G ++ E++ L+ G + + ++ +++ ID+D F+ Sbjct: 7 EELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFL 66 Query: 664 RCL 666 + Sbjct: 67 EFM 69 Score = 31.9 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 36/80 (45%), Gaps = 11/80 (13%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE++ D FR +F + A D I EL+ +L+ + + + + ++ D Sbjct: 5 SEEELSDLFR-MFDKNA--DGYIDLEELKIMLQA--------TGETITEDDIEELMKDGD 53 Query: 586 EDGSGKLGLKEFYILWTKIQ 605 ++ G++ EF ++ Sbjct: 54 KNNDGRIDYDEFLEFMKGVE 73 >2LVV-A nrPDB Length = 226 Score = 37.7 bits (86), Expect = 0.016, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 7/62 (11%) Query: 572 FSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGTMNS 624 + I +M D +D+DGS L L+EF K++++ ++ EID + SG + Sbjct: 130 YDIFELTVMFDTMDKDGSLLLELQEFKEALPKLKEWGVDITDATTVFNEIDTNGSGVVTF 189 Query: 625 YE 626 E Sbjct: 190 DE 191 Score = 29.6 bits (65), Expect = 5.4, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 38/103 (36%), Gaps = 19/103 (18%) Query: 609 KIYREIDVDRSGTMNSYEM----RKALEEAGFKLPCQLHQVIVARFA---------DDEL 655 +++++ D + +G + E+ L+ F L ++ F Sbjct: 55 ELFKQFDTNGTGKLGFREVLDGCYGILKLDEF--TTHLPDIVQRAFDKAKDLGNKVKGVG 112 Query: 656 IIDFDNFVRCLVRLEILFKIFK---QLDP-ENTGTIQLDLISW 694 D F+ + L ++ IF+ D + G++ L+L + Sbjct: 113 EEDLVEFLEFRLMLCYIYDIFELTVMFDTMDKDGSLLLELQEF 155 >2N8Y-A nrPDB Length = 153 Score = 37.7 bits (86), Expect = 0.017, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 29/78 (37%), Gaps = 6/78 (7%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC------QLHQVIVARFADDELII 657 + +++ + D D SGT+ E + L G+ + + +++ + ++ Sbjct: 9 MNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVV 68 Query: 658 DFDNFVRCLVRLEILFKI 675 F F+ + R Sbjct: 69 TFQAFIDFMSRETADTDT 86 >1ZFS-A nrPDB Length = 93 Score = 37.7 bits (86), Expect = 0.018, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 543 GEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWT 602 G+ ++S EL+ +L+ L+ D++ D + ++ LDE+G G++ +EF +L Sbjct: 23 GDKYKLSKKELKDLLQTELSSFLDVQKDA---DAVDKIMKELDENGDGEVDFQEFVVLVA 79 Query: 603 KIQKYQKIY 611 + + Sbjct: 80 ALTVACNNF 88 >2LCP-A nrPDB Length = 190 Score = 37.7 bits (86), Expect = 0.020, Method: Composition-based stats. Identities = 26/177 (14%), Positives = 58/177 (32%), Gaps = 33/177 (18%) Query: 528 EDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDED 587 E + + F + ++ A Q I ++ + K F + ++ DE+ Sbjct: 24 EKEVQQWYKGFIKDCPS-GQLDAAGFQKIYKQFFPFGDPTKFATF-------VFNVFDEN 75 Query: 588 GSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQ 641 G++ EF + +K + ++ D+D G + EM Sbjct: 76 KDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEM-------------- 121 Query: 642 LHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFS 698 ++ A + ++ + + +IF +D G +L L + S Sbjct: 122 -LDIVDAIYQMVGNTVELPE--EENTPEKRVDRIFAMMDKNADG--KLTLQEFQEGS 173 Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 46/115 (40%), Gaps = 8/115 (6%) Query: 490 EPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGE-DAEI 548 +P K F VF E K + I+A + + + R F + D I Sbjct: 60 DPTKFATFVFNVFDENKDGRIEFSEFIQA---LSVTSRGTLDEKLRWAFKLYDLDNDGYI 116 Query: 549 SAFELQTILR---RVLAKREDIKSDGFSIET-CKIMVDMLDEDGSGKLGLKEFYI 599 + E+ I+ +++ ++ + + E + M+D++ GKL L+EF Sbjct: 117 TRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQE 171 >1QLS-A nrPDB Length = 99 Score = 37.3 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 6/67 (8%) Query: 537 LFAQLAGEDA---EISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLG 593 +F + AG D +IS E + LA + D ++ M+ LD D G+L Sbjct: 18 IFQKHAGRDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLD---RMMKKLDLDSDGQLD 74 Query: 594 LKEFYIL 600 +EF L Sbjct: 75 FQEFLNL 81 >2I94-A nrPDB Length = 202 Score = 36.9 bits (84), Expect = 0.030, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 12/103 (11%) Query: 589 SGKLGLKEFYILWTKI------QKY-QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQ 641 SG++ +EF +++K + Y Q ++R D + GT++ E AL Q Sbjct: 41 SGRITRQEFQTIYSKFFPEADPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQ 100 Query: 642 LHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENT 684 + + + D N V LEI+ IFK + PE+T Sbjct: 101 KLEWAFSLYDVDGNGTISKNEV-----LEIVTAIFKMISPEDT 138 >3DTP-E nrPDB Length = 196 Score = 36.5 bits (83), Expect = 0.038, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 47/118 (39%), Gaps = 18/118 (15%) Query: 589 SGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVA 648 SG F ++Q++++ ++ ID D+ G ++ ++R + G Q +V Sbjct: 43 SGSNVFAMFTQ--HQVQEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMV- 99 Query: 649 RFADDELIIDFDNF-------VRCLVRLEILFKIFKQLDPENTG-----TIQLDLISW 694 A+ I+F F + +++ F D E G T++ L +W Sbjct: 100 --AEAPGPINFTMFLTIFGDRIAGTDEEDVIVNAFNLFD-EGDGKCKEETLKRSLTTW 154 >1S36-A nrPDB Length = 195 Score = 36.2 bits (82), Expect = 0.054, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 30/66 (45%), Gaps = 6/66 (9%) Query: 582 DMLDEDGSGKLGLKEFY------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 D+ D+DGSG + L E+ + + + +R D+D SG ++ EM + Sbjct: 120 DIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDLDNSGDLDVDEMTRQHLGFW 179 Query: 636 FKLPCQ 641 + L + Sbjct: 180 YTLDPE 185 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 32/86 (37%), Gaps = 8/86 (9%) Query: 602 TKIQKY-QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFA-DDELIIDF 659 T I+++ ++ D D SGT+ E + + +G + + D+ +D Sbjct: 109 TLIREWGDAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDLDNSGDLDV 168 Query: 660 DNFVRCLVRLEILFKIFKQLDPENTG 685 D R + LDPE G Sbjct: 169 DEMTR------QHLGFWYTLDPEADG 188 >2K2A-A nrPDB Length = 70 Score = 36.2 bits (82), Expect = 0.055, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQ-VIVARFADDELIIDFDNFV 663 Q+ ++ +R D + +G +++ MR+ L E L + +I AD +DF+ F+ Sbjct: 3 QELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFM 62 Query: 664 RCL 666 + Sbjct: 63 GVM 65 Score = 33.5 bits (75), Expect = 0.33, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 17/30 (56%) Query: 573 SIETCKIMVDMLDEDGSGKLGLKEFYILWT 602 S E M+D +D DGSG + +EF + T Sbjct: 37 SSEDLDAMIDEIDADGSGTVDFEEFMGVMT 66 >1N2D-A nrPDB Length = 148 Score = 36.2 bits (82), Expect = 0.055, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 37/103 (35%), Gaps = 16/103 (15%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFA--DDELIIDFDNFVRC 665 + I+ D G + + L G+ QL Q I+ + D + D + Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQ-ITG 65 Query: 666 LV-------------RLEILFKIFKQLDPENTGTIQLDLISWL 695 L+ + E K F+ D E+TG + + + ++ Sbjct: 66 LIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYM 108 Score = 34.6 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFD 660 K + + K ++ D + +G ++ ++R L G KL ++ +++ D ID+ Sbjct: 80 AKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYK 139 Query: 661 NFVRCLVR 668 F+ ++R Sbjct: 140 KFIEDVLR 147 >2OS8-B nrPDB Length = 157 Score = 36.2 bits (82), Expect = 0.055, Method: Composition-based stats. Identities = 21/116 (18%), Positives = 45/116 (38%), Gaps = 10/116 (8%) Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQL 642 M D+ SG L + +IQ+ ++ + ID +R G ++ ++++ G + P Sbjct: 1 MADKAASGVLT----KLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLG-RTPDDK 55 Query: 643 HQVIVARFADDELIID-----FDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLIS 693 + + A L F + + E + F D +T + ++ I Sbjct: 56 ELTAMLKEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIK 111 >2L2E-A nrPDB Length = 190 Score = 36.2 bits (82), Expect = 0.055, Method: Composition-based stats. Identities = 29/207 (14%), Positives = 73/207 (35%), Gaps = 50/207 (24%) Query: 506 KADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRE 565 K+ + D+++ + +++++ ++ F ++ E Q I ++ Sbjct: 3 KSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCP--SGHLNKSEFQKIYKQFF---P 57 Query: 566 DIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF--------------YILWTKIQKYQKIY 611 F+ + + ++ D D +G + KEF ++W + Sbjct: 58 FGDPSAFA----EYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWA--------F 105 Query: 612 REIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEI 671 + D+D +G ++ EM + ++ + + ++ +D + Sbjct: 106 QLYDLDNNGLISYDEMLRIVDA----IYKMVGSMVKLPEDEDTPE-------------KR 148 Query: 672 LFKIFKQLDPENTGTIQLDLISWLSFS 698 + KIF +D G QL L + S Sbjct: 149 VNKIFNMMDKNKDG--QLTLEEFCEGS 173 >1JF0-A nrPDB Length = 195 Score = 35.8 bits (81), Expect = 0.061, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 582 DMLDEDGSGKLGLKEFY------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635 D+ D+DGSG + L E+ + + +K ++ D+D SG ++ EM + Sbjct: 120 DIFDKDGSGTITLDEWKAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDEMTRQHLGFW 179 Query: 636 FKLPCQ 641 + L + Sbjct: 180 YTLDPE 185 Score = 29.6 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 33/110 (30%), Gaps = 24/110 (21%) Query: 594 LKEFYILWTK----------------IQKY-QKIYREIDVDRSGTMNSYEMRKALEEAGF 636 EF W I+++ ++ D D SGT+ E + +G Sbjct: 85 FPEFLEGWKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGRISGI 144 Query: 637 KLPCQLHQVIVARFA-DDELIIDFDNFVRCLVRLEILFKIFKQLDPENTG 685 + + D+ +D D R + LDPE G Sbjct: 145 SPSEEDCEKTFQHCDLDNSGELDVDEMTR------QHLGFWYTLDPEADG 188 >6EPA-A nrPDB Length = 187 Score = 35.8 bits (81), Expect = 0.063, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 42/115 (36%), Gaps = 24/115 (20%) Query: 583 MLDEDGSGKLGLKEFYILW------TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 + DE+ G + +EF +K +R DVD G + EM + Sbjct: 71 VFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEM--------Y 122 Query: 637 KLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDL 691 + ++Q++ + ++ + + KIF Q+D + + L+ Sbjct: 123 NIVDAIYQMVGQQPQTEDENTPQ----------KRVDKIFDQMDKNHDDRLTLEE 167 Score = 33.5 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 44/113 (38%), Gaps = 5/113 (4%) Query: 490 EPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEIS 549 +P K RVF E ++ I A N ++ RL+ D I+ Sbjct: 60 DPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYD--VDNDGYIT 117 Query: 550 AFELQTILR---RVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYI 599 E+ I+ +++ ++ + + + + D +D++ +L L+EF Sbjct: 118 REEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFRE 170 >1NSH-A nrPDB Length = 101 Score = 35.4 bits (80), Expect = 0.085, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 30/67 (44%), Gaps = 6/67 (8%) Query: 537 LFAQLAGEDAE---ISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLG 593 +F + AG+D +S E + + LA + D ++ M+ LD + G+L Sbjct: 16 VFQKYAGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLD---RMMKKLDLNSDGQLD 72 Query: 594 LKEFYIL 600 +EF L Sbjct: 73 FQEFLNL 79 >5PAL-A nrPDB Length = 109 Score = 35.4 bits (80), Expect = 0.092, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 8/81 (9%) Query: 590 GKLGLKEFYILW----TKIQKYQKIYREIDVDRSGTMNSYEMRKALE---EAGFKLPC-Q 641 G K F+ L + ++++ +D D+SG + E++ L+ G L + Sbjct: 22 GTFDYKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTE 81 Query: 642 LHQVIVARFADDELIIDFDNF 662 ++ A +D + I D F Sbjct: 82 TKALLAAGDSDHDGKIGADEF 102 Score = 34.6 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 28/71 (39%), Gaps = 6/71 (8%) Query: 531 GDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGS 589 + +F L + I EL+ +L+ A D+ + K ++ D D Sbjct: 40 DAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDL-----NDTETKALLAAGDSDHD 94 Query: 590 GKLGLKEFYIL 600 GK+G EF + Sbjct: 95 GKIGADEFAKM 105 >3PAT-A nrPDB Length = 110 Score = 35.4 bits (80), Expect = 0.094, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 6/70 (8%) Query: 532 DGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSG 590 + +++F + + I EL+ +L+ A D+ K + D+DG G Sbjct: 42 NDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTD-----AETKAFLKAADKDGDG 96 Query: 591 KLGLKEFYIL 600 K+G+ EF L Sbjct: 97 KIGIDEFETL 106 Score = 33.8 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 26/62 (41%), Gaps = 4/62 (6%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMR---KALEEAGFKLPC-QLHQVIVARFADDELIIDFD 660 +K+++ ID D SG + E++ K+ G L + + A D + I D Sbjct: 42 NDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGID 101 Query: 661 NF 662 F Sbjct: 102 EF 103 >3I5H-B nrPDB Length = 153 Score = 35.0 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 30/94 (31%), Gaps = 4/94 (4%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIID----F 659 +Q+ ++ + ID DR G + +++ G P ++ F Sbjct: 15 MQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAMLKECPGQLNFTAFLTLF 74 Query: 660 DNFVRCLVRLEILFKIFKQLDPENTGTIQLDLIS 693 V + L F D + G I D + Sbjct: 75 GEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLK 108 Score = 32.3 bits (72), Expect = 0.75, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 43/123 (34%), Gaps = 22/123 (17%) Query: 539 AQLAGEDAEISAFELQTILRRVLAKREDIKSDGF-SIETCKIM------------VDMLD 585 A+ A ++S ++Q + + D DGF +E K M ++ + Sbjct: 1 AEEAPRRVKLSQRQMQEL--KEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAML 58 Query: 586 EDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKL 638 ++ G+L F L+ + + + D D G + ++ LE G Sbjct: 59 KECPGQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMGDNF 118 Query: 639 PCQ 641 + Sbjct: 119 SKE 121 >2LUC-A nrPDB Length = 105 Score = 35.0 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 29/67 (43%), Gaps = 6/67 (8%) Query: 537 LFAQLAGEDA---EISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLG 593 +F + AG+D +S E + + LA + D ++ M+ LD + G+L Sbjct: 20 VFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLD---RMMKKLDTNSDGQLD 76 Query: 594 LKEFYIL 600 EF L Sbjct: 77 FSEFLNL 83 >2JU0-A nrPDB Length = 190 Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 44/118 (37%), Gaps = 23/118 (19%) Query: 580 MVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEMRKALEE 633 + + D+D +G + +EF + + +K + D++ G + EM + Sbjct: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM-LTIVA 126 Query: 634 AGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDL 691 + +K+ + ++ + + + KIFK +D G I LD Sbjct: 127 SVYKM---MGSMVTLNEDEATPEM-------------RVKKIFKLMDKNEDGYITLDE 168 >1NYA-A nrPDB Length = 176 Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 49/114 (42%), Gaps = 9/114 (7%) Query: 532 DGFRRLFAQLA-----GEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 + F LF LA G D ++ + + ++ ++ + + K +V M D+ Sbjct: 54 NAFGGLFDYLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDK 113 Query: 587 DGSGKLGLKEFYILWTKI----QKYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 + G++ EF T + + + + ++D + +G ++ E+ A+ + F Sbjct: 114 NADGQINADEFAAWLTALGMSKAEAAEAFNQVDTNGNGELSLDELLTAVRDFHF 167 >3KPX-A nrPDB Length = 198 Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 6/58 (10%) Query: 578 KIMVDMLDEDGSGKLGLKEFYI------LWTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 + + D+ D+DGSG + L E+ + + +K ++ D+D SG ++ EM + Sbjct: 119 EAVFDIFDKDGSGSISLDEWKTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEMTR 176 >5ZGM-A nrPDB Length = 110 Score = 34.6 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 8/81 (9%) Query: 590 GKLGLKEFYILW----TKIQKYQKIYREIDVDRSGTMNSYEMRKALE---EAGFKLPC-Q 641 G K F+ L + ++++ +D D+SG + E++ L+ G L + Sbjct: 23 GTFDYKRFFQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTE 82 Query: 642 LHQVIVARFADDELIIDFDNF 662 ++ A +D + I D F Sbjct: 83 TKALLAAGDSDHDGKIGADEF 103 Score = 33.5 bits (75), Expect = 0.29, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 29/71 (40%), Gaps = 6/71 (8%) Query: 531 GDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGS 589 + +F L + I EL+++L+ A D+ S K ++ D D Sbjct: 41 EAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDL-----SDTETKALLAAGDSDHD 95 Query: 590 GKLGLKEFYIL 600 GK+G EF + Sbjct: 96 GKIGADEFAKM 106 >5W1A-B nrPDB Length = 155 Score = 34.6 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 40/94 (42%), Gaps = 9/94 (9%) Query: 586 EDGSGKLGLKEFYILWTKIQK---------YQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 + K+ L EF ++++++K + + + D + +GTM E++ AL G Sbjct: 55 KRNEKKIKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGE 114 Query: 637 KLPCQLHQVIVARFADDELIIDFDNFVRCLVRLE 670 L + + + A D E F + L R+ Sbjct: 115 SLDDEQVETLFADCMDPEDDEGFIPYSPFLARMC 148 >1RTP-1 nrPDB Length = 109 Score = 34.6 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Query: 532 DGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSG 590 D +++F L + I EL +IL+ + D+ S + K ++ D+DG G Sbjct: 41 DDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDL-----SAKETKTLMAAGDKDGDG 95 Query: 591 KLGLKEFYIL 600 K+G++EF L Sbjct: 96 KIGVEEFSTL 105 >3TS5-B nrPDB Length = 161 Score = 34.6 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 45/115 (39%), Gaps = 7/115 (6%) Query: 585 DEDGSGKLGLKEFYILWTKI-QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLH 643 D++ + + F L K+ Q+ ++ + ID +R G ++ ++++ G + P Sbjct: 2 DKERAQRATSNVFARLPQKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLG-RTPDDKE 60 Query: 644 QVIVARFADDELIID-----FDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLIS 693 + + A L F + + E + F D +T + ++ I Sbjct: 61 LTAMLKEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIK 115 >3J04-B nrPDB Length = 143 Score = 34.6 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 47/105 (44%), Gaps = 10/105 (9%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDN 661 ++IQ++++ + ID +R G ++ ++ L G + + ++ ++ I+F Sbjct: 4 SQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEGMM---SEAPGPINFTM 60 Query: 662 FVRCL-VRL------EILFKIFKQLDPENTGTIQLDLISWLSFSV 699 F+ +L +++ F D E +G I D + L ++ Sbjct: 61 FLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTM 105 Score = 31.5 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 20/149 (13%), Positives = 49/149 (32%), Gaps = 21/149 (14%) Query: 527 EEDIGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 ++ F+ F + D I +L +L + D +G + Sbjct: 2 DQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEG------------MM 49 Query: 586 EDGSGKLGLKEFYILWTKIQK-------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKL 638 + G + F ++ + + + D + SG ++ +R+ L G + Sbjct: 50 SEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRF 109 Query: 639 P-CQLHQVIVARFADDELIIDFDNFVRCL 666 ++ ++ D + ++ F R L Sbjct: 110 TDEEVDEMYREAPIDKKGNFNYVEFTRIL 138 >1G33-A nrPDB Length = 73 Score = 34.2 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Query: 532 DGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSG 590 D +++F L + I EL +IL+ + D+ S + K ++ D+DG G Sbjct: 5 DDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDL-----SAKETKTLMAAGDKDGDG 59 Query: 591 KLGLKEFYIL 600 K+G++EF L Sbjct: 60 KIGVEEFSTL 69 >2EC6-B nrPDB Length = 133 Score = 33.8 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 37/95 (38%), Gaps = 6/95 (6%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIID----- 658 +Q+ ++ + ID +R G ++ ++++ G + P + + A L Sbjct: 1 MQEMKEAFTMIDQNRDGFIDINDLKEEFSSLG-RTPDDKELTAMLKEAPGPLNFTMFLSI 59 Query: 659 FDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLIS 693 F + + E + F D + T + ++ I Sbjct: 60 FSDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIK 94 Score = 28.8 bits (63), Expect = 8.3, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 32/94 (34%), Gaps = 8/94 (8%) Query: 578 KIMVDMLDEDGSGKLGLKEFYILWT-------KIQKYQKIYREIDVDRSGTMNSYEMRKA 630 K + ML ++ G L F +++ + + + D D + +N ++ Sbjct: 38 KELTAML-KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDL 96 Query: 631 LEEAGFKLPCQLHQVIVARFADDELIIDFDNFVR 664 LE G ++ + D+ FV Sbjct: 97 LENMGDNFNKDEMRMTFKEAPVEGGKFDYVRFVA 130 >2L0P-A nrPDB Length = 94 Score = 33.8 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 39/79 (49%), Gaps = 6/79 (7%) Query: 536 RLFAQLAGEDAE---ISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKL 592 +F +G++ + +S EL+ +L+ L+ D + D ++ ++ LDE+G G++ Sbjct: 14 NVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKD---VDAVDKVMKELDENGDGEV 70 Query: 593 GLKEFYILWTKIQKYQKIY 611 +E+ +L + + Sbjct: 71 DFQEYVVLVAALTVACNNF 89 >2FCE-A nrPDB Length = 70 Score = 33.8 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFADDELIIDFD 660 K + + K ++ D + +G ++ ++R L G KL ++ +++ D ID+ Sbjct: 2 AKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYK 61 Query: 661 NFVRCLVR 668 F+ ++R Sbjct: 62 KFIEDVLR 69 >2QJ0-A nrPDB Length = 982 Score = 33.8 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 38/196 (19%), Positives = 70/196 (35%), Gaps = 23/196 (11%) Query: 482 YVLVPS-----TFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRR 536 Y +PS ++ N DF +R + D + DE +N+ E+ + ++ + R Sbjct: 673 YYKIPSYKNQLIWQSQNNADFFVRFVARMLNDLTFLLDEGLSNLAEVHNIQNELDNRARG 732 Query: 537 LFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKE 596 A E ELQT R+ + KS + + ++ +D E Sbjct: 733 -----APPTREEEDKELQT---RLASASRQAKSSCGLADKSMKLFEIYSKDIPAAFVTPE 784 Query: 597 FYILWTKIQKY--------QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVA 648 + Y + ++ +S + N ++ KAL L Q ++ Sbjct: 785 IVYRLASMLNYNLESLVGPKCGELKVKDPQSYSFNPKDLLKALTTVYINLSEQ--SEFIS 842 Query: 649 RFADDELIIDFDNFVR 664 A DE + + FVR Sbjct: 843 AVAKDERSFNRNLFVR 858 >1DFK-Y nrPDB Length = 139 Score = 33.8 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 40/97 (41%), Gaps = 6/97 (6%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIID--- 658 +IQ+ ++ + IDVDR G ++ +++ E+ G + P + + A L Sbjct: 4 KQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLG-RAPDDKELTAMLKEAPGPLNFTMFL 62 Query: 659 --FDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLIS 693 F + + E + F D + T + ++ I Sbjct: 63 SIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIK 99 >1B7T-Y nrPDB Length = 156 Score = 33.8 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 40/97 (41%), Gaps = 6/97 (6%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIID--- 658 +IQ+ ++ + IDVDR G ++ +++ E+ G + P + + A L Sbjct: 15 KQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLG-RAPDDKELTAMLKEAPGPLNFTMFL 73 Query: 659 --FDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLIS 693 F + + E + F D + T + ++ I Sbjct: 74 SIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIK 110 >3GMC-A nrPDB Length = 415 Score = 33.8 bits (76), Expect = 0.29, Method: Composition-based stats. Identities = 40/173 (23%), Positives = 64/173 (36%), Gaps = 35/173 (20%) Query: 232 LEKGSLLGCSIDITS-AADSEAVTYQKLVKGH---AYSVTGAEEVESSG----------- 276 + + LG I + S A ++ V L G A + GA+ V S Sbjct: 150 VNRARALGVDISVNSEAVAADPVGRLTLQTGEVLEADLIVGADGVGSKVRDSIGFKQDRW 209 Query: 277 -SLQKLIRIRNPWGQVEW-TGKWNDNCPSWNTVDPEVRANLTERQEDGEFWMSF------ 328 S LIR+ P + E G+W++ WN P V+ L + E ++ Sbjct: 210 VSKDGLIRLIVPRMKKELGHGEWDNTIDMWNFW-PRVQRILYSPCNENELYLGLMAPAAD 268 Query: 329 ----------SDFLRHYSRLEICNLTPDTLTCDSYKKWKLTKMDGNWRRGSTA 371 ++ + LE C + L Y K++ TK+D +W RG A Sbjct: 269 PRGSSVPIDLEVWVEMFPFLEPCLIEAAKLKTARYDKYETTKLD-SWTRGKVA 320 >2KQY-A nrPDB Length = 108 Score = 33.5 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 6/74 (8%) Query: 528 EDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDE 586 D +++F L + I ELQ L+ + + S K + D Sbjct: 37 SKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTS-----AETKAFLAAGDT 91 Query: 587 DGSGKLGLKEFYIL 600 DG GK+G++EF L Sbjct: 92 DGDGKIGVEEFQSL 105 >1CB1-A nrPDB Length = 78 Score = 33.1 bits (74), Expect = 0.39, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 32/67 (47%), Gaps = 6/67 (8%) Query: 538 FAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 +A G+ ++S EL+ ++ + + S T + LD++G G++ +EF Sbjct: 16 YAAKEGDPNQLSKEELKQLI------QAEFPSLLKGPRTLDDLFQELDKNGDGEVSFEEF 69 Query: 598 YILWTKI 604 +L KI Sbjct: 70 QVLVKKI 76 >1JBA-A nrPDB Length = 204 Score = 33.1 bits (74), Expect = 0.40, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 44/121 (36%), Gaps = 18/121 (14%) Query: 577 CKIMVDMLDEDGSGKLGLKEFYILWTKIQ------KYQKIYREIDVDRSGTMNSYEMRKA 630 + M D +G + E+ + K + ++ D DR+G ++ E+ Sbjct: 61 VEAMFRAFDTNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDI 120 Query: 631 LEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLD 690 +E +KL V A+ + + E++ +IF +D G + L+ Sbjct: 121 VESI-YKLKKACS---VEVEAEQQGKLLTPE--------EVVDRIFLLVDENGDGQLSLN 168 Query: 691 L 691 Sbjct: 169 E 169 >5XOP-A nrPDB Length = 66 Score = 33.1 bits (74), Expect = 0.42, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 30/59 (50%), Gaps = 1/59 (1%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVAR-FADDELIIDFDNFVRC 665 + +++EIDV+ G ++ E++ + + QL Q+I D + IDF+ F + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKF 61 >2D8N-A nrPDB Length = 207 Score = 33.1 bits (74), Expect = 0.45, Method: Composition-based stats. Identities = 30/135 (22%), Positives = 53/135 (39%), Gaps = 16/135 (11%) Query: 557 LRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI------QKY-QK 609 L + + + + + E C L + +G++ ++F ++ K + Y Q Sbjct: 16 LSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQH 75 Query: 610 IYREIDVDRSGTMNSYEMRKAL--EEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLV 667 ++R D + GT++ E AL AG K +L D I + Sbjct: 76 VFRSFDSNLDGTLDFKEYVIALHMTTAG-KTNQKLEWAFSLYDVDGNGTISKNE------ 128 Query: 668 RLEILFKIFKQLDPE 682 LEI+ IFK + PE Sbjct: 129 VLEIVMAIFKMITPE 143 >2AUC-A nrPDB Length = 126 Score = 33.1 bits (74), Expect = 0.46, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 24/54 (44%) Query: 603 KIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELI 656 +++ K++ D + SG + +M+ L G L Q + F+ ++ I Sbjct: 63 NMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQEANDALNAFSSEDRI 116 >3DD4-A nrPDB Length = 229 Score = 32.7 bits (73), Expect = 0.55, Method: Composition-based stats. Identities = 17/120 (14%), Positives = 43/120 (35%), Gaps = 19/120 (15%) Query: 580 MVDMLDEDGSGKLGLKEF-YILW-----TKIQKYQKIYREIDVDRSGTMNSYE----MRK 629 + + D D +G + ++F L T +K + D+++ G + E M+ Sbjct: 107 LFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA 166 Query: 630 ALEEAG--------FKLPCQLHQVIVAR-FADDELIIDFDNFVRCLVRLEILFKIFKQLD 680 + G P Q + + + + ++ D F+ + E + + + + Sbjct: 167 IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFE 226 >1C7W-A nrPDB Length = 81 Score = 32.7 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 28/67 (41%), Gaps = 7/67 (10%) Query: 575 ETCKIMVDMLDEDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEM 627 E + D +G G + EF + K+ + ++ +E D D +G ++ E Sbjct: 8 EEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEF 67 Query: 628 RKALEEA 634 ++++ Sbjct: 68 MDLIKKS 74 Score = 30.0 bits (66), Expect = 4.1, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 10/84 (11%) Query: 526 NEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLD 585 +EE+I F+ +F A D I E + I+++V + + + + D Sbjct: 6 DEEEILRAFK-VFD--ANGDGVIDFDEFKFIMQKVGE-------EPLTDAEVEEAMKEAD 55 Query: 586 EDGSGKLGLKEFYILWTKIQKYQK 609 EDG+G + + EF L K + K Sbjct: 56 EDGNGVIDIPEFMDLIKKSKNALK 79 Score = 29.6 bits (65), Expect = 4.6, Method: Composition-based stats. Identities = 8/61 (13%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFK--LPCQLHQVIVARFADDELIIDFDNF 662 ++ + ++ D + G ++ E + +++ G + ++ + + D +ID F Sbjct: 8 EEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEF 67 Query: 663 V 663 + Sbjct: 68 M 68 >1RK9-A nrPDB Length = 110 Score = 32.7 bits (73), Expect = 0.62, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 6/70 (8%) Query: 532 DGFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSG 590 D +++F L + I EL IL+ D+ S + K+++ D+DG G Sbjct: 42 DDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDL-----SAKETKMLMAAGDKDGDG 96 Query: 591 KLGLKEFYIL 600 K+G+ EF L Sbjct: 97 KIGVDEFSTL 106 >5LNB-B nrPDB Length = 310 Score = 32.3 bits (72), Expect = 0.68, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 46/133 (34%), Gaps = 14/133 (10%) Query: 436 VPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPGEYVLVPSTFEPH--- 492 + + + + +HL +FF T +D + N+++ +N L +YV++P H Sbjct: 66 IEKSIIKREQVHLMSSFFYTKLISNPADYYSNVKKWVNNTDLFSKKYVVIPINISYHWFS 125 Query: 493 ---KNGDFCIRVFSEKKADYQTVDDEIEAN--------IEEIEANEEDIGDGFRRLFAQL 541 N D + K + DEI N + + D + Sbjct: 126 CIITNLDAILDFHQNKDKNDAINSDEISINNPLVNILTFDSLRQTHSREIDPIKEFLISY 185 Query: 542 AGEDAEISAFELQ 554 A + I + Q Sbjct: 186 ALDKYSIQLDKTQ 198 >3AQL-A nrPDB Length = 415 Score = 32.3 bits (72), Expect = 0.84, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 5/78 (6%) Query: 450 KNFFLTTRARERS--DTFINLREVLNRFKLPP---GEYVLVPSTFEPHKNGDFCIRVFSE 504 K+F +TT A F N R V RF+L G ++ +TF H G+ R S+ Sbjct: 52 KDFDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQ 111 Query: 505 KKADYQTVDDEIEANIEE 522 + + + D I +IEE Sbjct: 112 RGQNGMLLRDNIFGSIEE 129 >1TIZ-A nrPDB Length = 67 Score = 31.9 bits (71), Expect = 0.87, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 6/65 (9%) Query: 576 TCKIMVDMLDEDGSGKLGLKEFYIL------WTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 + K + + D++ GKL L EF + + + K + EIDVD +G +N+ E Sbjct: 2 SAKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTS 61 Query: 630 ALEEA 634 +E+ Sbjct: 62 CIEKM 66 >1DGU-A nrPDB Length = 183 Score = 31.9 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 18/115 (15%), Positives = 41/115 (35%), Gaps = 10/115 (8%) Query: 525 ANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDML 584 +++I RR L E + + + + ++K++ F C++ Sbjct: 14 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 73 Query: 585 DEDGSGKLGLKEFYILWTKIQKYQK-------IYREIDVDRSGTMNSYEMRKALE 632 +D L ++F L + +R D D GT+N ++ + + Sbjct: 74 AKD---SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVN 125 Score = 28.8 bits (63), Expect = 7.9, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 32/73 (43%), Gaps = 7/73 (9%) Query: 544 EDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDML----DEDGSGKLGLKEFYI 599 +D ++ +L ++ + + ED + S K ++D + D D G + L EF Sbjct: 111 DDGTLNREDLSRLVNCLTGEGEDTR---LSASEMKQLIDNILEESDIDRDGTINLSEFQH 167 Query: 600 LWTKIQKYQKIYR 612 + ++ + ++ Sbjct: 168 VISRSPDFASSFK 180 >2LM5-A nrPDB Length = 214 Score = 31.9 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 18/115 (15%), Positives = 41/115 (35%), Gaps = 10/115 (8%) Query: 525 ANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDML 584 +++I RR L E + + + + ++K++ F C++ Sbjct: 45 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 104 Query: 585 DEDGSGKLGLKEFYILWTKIQKYQK-------IYREIDVDRSGTMNSYEMRKALE 632 +D L ++F L + +R D D GT+N ++ + + Sbjct: 105 AKD---SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVN 156 Score = 28.8 bits (63), Expect = 8.0, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 32/73 (43%), Gaps = 7/73 (9%) Query: 544 EDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDML----DEDGSGKLGLKEFYI 599 +D ++ +L ++ + + ED + S K ++D + D D G + L EF Sbjct: 142 DDGTLNREDLSRLVNCLTGEGEDTR---LSASEMKQLIDNILEESDIDRDGTINLSEFQH 198 Query: 600 LWTKIQKYQKIYR 612 + ++ + ++ Sbjct: 199 VISRSPDFASSFK 211 >1SL8-A nrPDB Length = 191 Score = 31.9 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 29/56 (51%), Gaps = 6/56 (10%) Query: 580 MVDMLDEDGSGKLGLKEFY------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 + D++D+D +G + L E+ + + ++ +R D+D SG ++ EM + Sbjct: 114 LFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 >1UHK-A nrPDB Length = 191 Score = 31.9 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 29/56 (51%), Gaps = 6/56 (10%) Query: 580 MVDMLDEDGSGKLGLKEFY------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 + D++D+D +G + L E+ + + ++ +R D+D SG ++ EM + Sbjct: 114 LFDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 >2NLN-A nrPDB Length = 108 Score = 31.5 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 25/60 (41%), Gaps = 5/60 (8%) Query: 544 EDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTK 603 + + EL+ L++ + ++ K ++D D DG GK+G EF + Sbjct: 54 QSGYLDGDELKYFLQKFQSDARELTES-----ETKSLMDAADNDGDGKIGADEFQEMVHS 108 Score = 30.4 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 28/59 (47%), Gaps = 4/59 (6%) Query: 608 QKIYREIDVDRSGTMNSYEMR---KALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 + I+R ID D+SG ++ E++ + + +L + ++ A D + I D F Sbjct: 44 KDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADEF 102 >1TTX-A nrPDB Length = 109 Score = 31.5 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 605 QKYQKIYREIDVDRSGTMNSYEMR---KALEEAGFKLPC-QLHQVIVARFADDELIIDFD 660 + + ++R ID D+SG ++ E++ + E +L + ++ A D + I + Sbjct: 42 NQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAE 101 Query: 661 NF 662 F Sbjct: 102 EF 103 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 25/60 (41%), Gaps = 5/60 (8%) Query: 544 EDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTK 603 + + EL+ L++ + ++ K ++ D DG GK+G +EF + Sbjct: 55 QSGYLDEEELKFFLQKFESGARELTES-----ETKSLMAAADNDGDGKIGAEEFQEMVHS 109 >2M7L-A nrPDB Length = 144 Score = 31.1 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 27/69 (39%), Gaps = 6/69 (8%) Query: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGF------KLPCQLHQVIVARFADDELII 657 +Q++++ + D + G ++ E R L G + I E + Sbjct: 11 MQEFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQYDAIYNNVTKGENGV 70 Query: 658 DFDNFVRCL 666 FDN+V+ + Sbjct: 71 SFDNYVQYM 79 >3AKA-A nrPDB Length = 166 Score = 31.1 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 34/98 (34%), Gaps = 16/98 (16%) Query: 585 DEDGSGKLGLKEF-----YILWTKIQKYQKIYREI--------DVDRSGTMNSYEMRKAL 631 D DG ++ +EF L K ++ +I R D D G + + +AL Sbjct: 65 DRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTARAL 124 Query: 632 EEAGFKLPCQL-HQVIVARFADDELIIDFDNFVRCLVR 668 G +P L Q A D + + V R Sbjct: 125 TAFG--VPEDLARQAAAALDTDGDGKVGETEIVPAFAR 160 >4RI0-A nrPDB Length = 332 Score = 31.1 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 32/75 (42%), Gaps = 4/75 (5%) Query: 2 AGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQ----DPSFPALPSS 57 AGI+ + DR ++ IK + + +R + + + +P FP + S Sbjct: 197 AGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMRTITPSLVDELKASNPDFPEVSSG 256 Query: 58 LGFKELGPYSSKTRG 72 + +E+ P S RG Sbjct: 257 IYVQEVAPNSPSQRG 271 >5B7X-A nrPDB Length = 156 Score = 31.1 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 40/105 (38%), Gaps = 17/105 (16%) Query: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILW--- 601 D +I +L T++R + + + + +G +++F ++ Sbjct: 27 DGKIDVKQLGTLIRSLGCAPTE--------DEVNSYIKEFAIEGE-TFQIEQFELIMERE 77 Query: 602 -----TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQ 641 T+ K +K + D D+ G + + ++ L G K+ + Sbjct: 78 QSKPDTREIKLRKAFEVFDQDKDGKIKASDLAHNLTTVGDKMTKE 122 >2KYF-A nrPDB Length = 108 Score = 30.8 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 30/59 (50%), Gaps = 4/59 (6%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALE--EAGFKL--PCQLHQVIVARFADDELIIDFDNF 662 ++I+R +D D+SG + E++ L+ E+G ++ + + A D + I + F Sbjct: 44 KEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFLAAADHDGDGKIGAEEF 102 Score = 30.4 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 34/94 (36%), Gaps = 6/94 (6%) Query: 508 DYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGE-DAEISAFELQTILRRVLAKRED 566 D Q D +I + + +F L + I EL+ L+R + Sbjct: 17 DCQAPDSFSPKKFFQISGMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARV 76 Query: 567 IKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL 600 + + K + D DG GK+G +EF + Sbjct: 77 LTAS-----ETKTFLAAADHDGDGKIGAEEFQEM 105 >5ZH6-A nrPDB Length = 107 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 26/58 (44%), Gaps = 4/58 (6%) Query: 609 KIYREIDVDRSGTMNSYEMR---KALEEAGFKLPC-QLHQVIVARFADDELIIDFDNF 662 K++ +D DRSG + E++ + +L + + + A +D + I D F Sbjct: 44 KVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDSDHDGKIGVDEF 101 >5XND-A nrPDB Length = 114 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEE--AGFK-LPC-QLHQVIVARFADDELII 657 + +K + ID D+SG + E++ L+ AG + L + + A +D + I Sbjct: 44 KSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDGDGKI 103 Query: 658 DFDNF 662 D F Sbjct: 104 GIDEF 108 >5VE9-A nrPDB Length = 91 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 1/57 (1%) Query: 611 YREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARF-ADDELIIDFDNFVRCL 666 +R ID D+ G + E + + F + F D + ID+ FV L Sbjct: 33 FRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAAL 89 Score = 29.6 bits (65), Expect = 5.3, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 22/54 (40%), Gaps = 6/54 (11%) Query: 584 LDEDGSGKLGLKEFYI------LWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631 +D+D GK+ +EF T + + D D G ++ YE AL Sbjct: 36 IDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAAL 89 >3CS1-A nrPDB Length = 219 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 33/185 (17%), Positives = 77/185 (41%), Gaps = 34/185 (18%) Query: 457 RARERSDTFINLREVLNRFKLPPGEY--VLVPSTFEPHKNGDFCIRVFSEKKADYQTVDD 514 +A++R + + +R+ + R K + + + F+ ++ G C + E + V Sbjct: 23 KAKDRKEAWERIRQAIPREKTAEAKQRRIELFKKFDKNETGKLC---YDEVYSGCLEV-- 77 Query: 515 EIEANIEEIEANEEDIG----DGFRRLFAQLAGEDAE--ISAFELQTILRRVLAKREDIK 568 ++E + DI D R L ++L + +E + E + +L + Sbjct: 78 ---LKLDEFTSRVRDITKRAFDKSRTLGSKLENKGSEDFVEFLEFRLMLCYI-------- 126 Query: 569 SDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKY-------QKIYREIDVDRSGT 621 D F + +M D +D G+ + +EF K++ + +++E+D + +G+ Sbjct: 127 YDFFELT---VMFDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAALFKELDKNGTGS 183 Query: 622 MNSYE 626 + E Sbjct: 184 VTFDE 188 >2M7M-A nrPDB Length = 66 Score = 30.4 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Query: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVAR-FADDELIIDFDNFVRC 665 + +++EIDV+ G ++ E++ + + QL Q+I AD ID + F + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKF 61 >5LCW-N nrPDB Length = 822 Score = 30.4 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 21/105 (20%), Positives = 40/105 (38%), Gaps = 11/105 (10%) Query: 478 PPGEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDE-----------IEANIEEIEAN 526 PPG + ++ ++ I E + + D+ I+A + +E+ Sbjct: 709 PPGTFSVIEEERPQDRDNMVLIDSDDESDSGMASQADQKEEELLLFWTYIQAMLTNLESL 768 Query: 527 EEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDG 571 D R+F AEI ELQ L++ + ++ + S G Sbjct: 769 SLDRIYNMLRMFVVTGPALAEIDLQELQGYLQKKVRDQQLVYSAG 813 >2Y5I-A nrPDB Length = 99 Score = 30.4 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 4/78 (5%) Query: 543 GEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWT 602 G+ ++S EL+ +L L + D +E +++ LD + ++ EF +L Sbjct: 24 GDKYKLSKGELKELLNAELTDFLMSQKDPMLVE---KIMNDLDSNKDNEVDFNEFVVLVA 80 Query: 603 KIQ-KYQKIYREIDVDRS 619 + ++E RS Sbjct: 81 ALTVACNDFFQEQQKKRS 98 >2MA2-A nrPDB Length = 81 Score = 30.4 bits (67), Expect = 2.9, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 5/58 (8%) Query: 574 IETCKIMVDM----LDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEM 627 +E + MV+ D DG G + +EF I+ Y + ++D ++ G ++ EM Sbjct: 8 VEHIEKMVESVFRNFDVDGDGHISQEEFQIIRGNF-PYLSAFGDLDQNQDGCISREEM 64 >1KQV-A nrPDB Length = 79 Score = 30.4 bits (67), Expect = 2.9, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 35/73 (47%), Gaps = 3/73 (4%) Query: 532 DGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGK 591 + + +F + A ++ + + + + + + + +++ + + LD++G G+ Sbjct: 8 EELKGIFEKYAAKEGDPNQLSKEELKLLLQTEFPSLLKGMSTLDE---LFEELDKNGDGE 64 Query: 592 LGLKEFYILWTKI 604 + +EF +L KI Sbjct: 65 VSFEEFQVLVKKI 77 >2I18-A nrPDB Length = 64 Score = 30.4 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 26/57 (45%), Gaps = 3/57 (5%) Query: 611 YREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLV 667 Y+ +DVD G + E+ ++ G ++ + ++ A+ + I + F+ + Sbjct: 11 YKLMDVDGDGKLTKEEVTSFFKKHGI---EKVAEQVMKADANGDGYITLEEFLEFSL 64 >6AGH-A nrPDB Length = 339 Score = 30.4 bits (67), Expect = 3.1, Method: Composition-based stats. Identities = 45/222 (20%), Positives = 81/222 (36%), Gaps = 36/222 (16%) Query: 480 GEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFA 539 GEY + P DF V E+ +V + +IE+ + + G G F Sbjct: 41 GEYYMTPR--------DFLFSVMFEQMERKTSVKKLTKKDIEDTLSGIQTAGCG--STFF 90 Query: 540 QLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYI 599 + G+ IS E +L + GF + MLD DG+ + +EF+ Sbjct: 91 RDLGDKGLISYTEYLFLLTILTKPH-----SGFHVA-----FKMLDTDGNEMIEKREFFK 140 Query: 600 LWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARF--ADDELII 657 L I K Q + + +G ++A+ + +++ + RF + + Sbjct: 141 LQKIISK-QDDLMTVKTNETG------YQEAIVK-----EPEINTTLQMRFFGKRGQRKL 188 Query: 658 DFDNFVRCLVRLEILFK--IFKQLDPENTGTIQLDLISWLSF 697 + F R + L+ + F Q + + D WL F Sbjct: 189 HYKEFRRFMENLQTEIQEMEFLQFSKGLSFMRKEDFAEWLLF 230 >4NSC-A nrPDB Length = 401 Score = 30.0 bits (66), Expect = 3.7, Method: Composition-based stats. Identities = 24/142 (16%), Positives = 48/142 (33%), Gaps = 27/142 (19%) Query: 583 MLDEDGSGKLGLKEFYILWTKIQKYQK-IYREIDVDRSGTMNSYEMRKALEEAGF----- 636 M D +G G++ ++EF + + I+ R D +G + AL F Sbjct: 154 MFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLK 213 Query: 637 -------------KLPCQLHQVIVARFADDELIIDFDNFVRCLV--------RLEILFKI 675 KL + ++ R + I F L+ +L + + Sbjct: 214 GKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQ 273 Query: 676 FKQLDPENTGTIQLDLISWLSF 697 K+ E G ++ ++ +F Sbjct: 274 LKKHFKEGKGLTFQEVENFFTF 295 >4NQG-A nrPDB Length = 197 Score = 30.0 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 27/56 (48%), Gaps = 6/56 (10%) Query: 580 MVDMLDEDGSGKLGLKEF------YILWTKIQKYQKIYREIDVDRSGTMNSYEMRK 629 + D++D+DG+G + L E+ + + + + D+D G ++ EM + Sbjct: 119 LFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDEMTR 174 >6EAZ-A nrPDB Length = 379 Score = 30.0 bits (66), Expect = 4.0, Method: Composition-based stats. Identities = 47/222 (21%), Positives = 75/222 (33%), Gaps = 36/222 (16%) Query: 480 GEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFA 539 GEY + P DF V E+ V + +IE++ + F Sbjct: 44 GEYYMTPR--------DFLFSVMFEQVERKTLVKKLAKKDIEDV-LSGIQTARCGSTFFR 94 Query: 540 QLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYI 599 L G+ IS E +L + GF + MLD DG+ + KEF Sbjct: 95 DL-GDKGVISYTEYLFLLTILTKPH-----SGFHVA-----FKMLDVDGNEMIERKEFVK 143 Query: 600 LWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARF--ADDELII 657 L I K Q ++ + + + + ++E G Q+ RF E + Sbjct: 144 LQKIISK-QDGFKTVKTNETEYQDP-----TVKEPGVNTTLQV------RFFGKRGEKKL 191 Query: 658 DFDNFVRCLVRLEILFK--IFKQLDPENTGTIQLDLISWLSF 697 + F R + L+ + F Q + D WL F Sbjct: 192 HYKEFRRFMENLQTEVQEMEFLQFSKGLNFMRKEDFAEWLLF 233 >2NA0-A nrPDB Length = 205 Score = 30.0 bits (66), Expect = 4.0, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 24/52 (46%) Query: 548 ISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYI 599 I EL TI+R + A S + E + +D +G G+L L+EF Sbjct: 107 IDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFME 158 >6AGI-A nrPDB Length = 382 Score = 29.6 bits (65), Expect = 4.4, Method: Composition-based stats. Identities = 34/147 (23%), Positives = 61/147 (41%), Gaps = 23/147 (15%) Query: 496 DFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQT 555 DF + V +++ +T + + ++ A + G +LF L E IS E Sbjct: 37 DFILAVTTDEPKVAKTWKSLSKQELNQMLAETPPVWKGSSKLFRNLK-EKGVISYTEYLF 95 Query: 556 ILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREID 615 +L + GF +I +M D DG+ + KEF +L Q+I+R+ + Sbjct: 96 LLCILTKPHA-----GF-----RIAFNMFDTDGNEMVDKKEFLVL-------QEIFRKKN 138 Query: 616 VDRSGTMNSYEMRKA---LEEAGFKLP 639 R + E ++A L+ G+ P Sbjct: 139 EKRE--IKGDEEKRAMLRLQLYGYHSP 163 Score = 28.8 bits (63), Expect = 8.8, Method: Composition-based stats. Identities = 21/126 (16%), Positives = 45/126 (35%), Gaps = 21/126 (16%) Query: 580 MVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLP 639 +V + G +L ++FY +Q ++ + S MN+ + Sbjct: 213 LVHFFGKKGKAELNFEDFYRFMDNLQT--EVLEIEFLSYSNGMNT-------------IS 257 Query: 640 CQLHQVIVARFADDELIIDFDNFVRCL------VRLEILFKIFKQLDPENTGTIQLDLIS 693 + I+ R+ + E F VR + + F+ L+ I L++ + Sbjct: 258 EEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYN 317 Query: 694 WLSFSV 699 + S S+ Sbjct: 318 FASRSI 323 >4PCW-A nrPDB Length = 94 Score = 29.6 bits (65), Expect = 5.1, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 26/65 (40%) Query: 536 RLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLK 595 LF Q + +D + + + + I + + + +D LD D + K+ Sbjct: 15 NLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDHLDIDHNKKIDFT 74 Query: 596 EFYIL 600 EF ++ Sbjct: 75 EFLLM 79 >2NCO-A nrPDB Length = 102 Score = 29.6 bits (65), Expect = 5.2, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 19/28 (67%) Query: 668 RLEILFKIFKQLDPENTGTIQLDLISWL 695 +L++ ++FK+ D + +G +Q D I+ L Sbjct: 13 KLDVARRLFKRYDKDGSGQLQDDEIAGL 40 >6ED3-A nrPDB Length = 848 Score = 29.6 bits (65), Expect = 5.3, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 24/46 (52%), Gaps = 2/46 (4%) Query: 192 YEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSL 237 YEA GG TE + + E+ K P++F ++ + L++G L Sbjct: 658 YEA--GGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQVLDEGRL 701 >5CPV-A nrPDB Length = 109 Score = 29.2 bits (64), Expect = 5.9, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 25/68 (36%), Gaps = 4/68 (5%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMR---KALEEAGFKLPC-QLHQVIVARFADDELII 657 +K + ID D+SG + E++ + + L + + A +D + I Sbjct: 39 KSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFLKAGDSDGDGKI 98 Query: 658 DFDNFVRC 665 D F Sbjct: 99 GVDEFTAL 106 >4OCI-A nrPDB Length = 146 Score = 29.2 bits (64), Expect = 6.3, Method: Composition-based stats. Identities = 10/71 (14%), Positives = 29/71 (40%), Gaps = 1/71 (1%) Query: 594 LKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPC-QLHQVIVARFAD 652 + + + +D D+ G + + E+R+ L G + ++ + D Sbjct: 66 FSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEITDLFTFMGID 125 Query: 653 DELIIDFDNFV 663 ++ ++ D+F+ Sbjct: 126 EQGVVKVDDFI 136 >4PAL-A nrPDB Length = 108 Score = 28.8 bits (63), Expect = 8.4, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 25/65 (38%), Gaps = 4/65 (6%) Query: 602 TKIQKYQKIYREIDVDRSGTMNSYEMR---KALEEAGFKLPC-QLHQVIVARFADDELII 657 + +K + ID D+SG + E++ + + L + + D + +I Sbjct: 38 KSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLADGDKDGDGMI 97 Query: 658 DFDNF 662 D F Sbjct: 98 GVDEF 102 >6IIE-A nrPDB Length = 93 Score = 28.4 bits (62), Expect = 9.7, Method: Composition-based stats. Identities = 7/24 (29%), Positives = 15/24 (62%) Query: 611 YREIDVDRSGTMNSYEMRKALEEA 634 ++ D DR+G ++S E+ K + + Sbjct: 15 FKLYDTDRNGILDSSEVDKIILQM 38 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.138 0.411 Lambda K H 0.267 0.0428 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,117,472 Number of Sequences: 36641 Number of extensions: 1420059 Number of successful extensions: 5077 Number of sequences better than 10.0: 250 Number of HSP's better than 10.0 without gapping: 202 Number of HSP's successfully gapped in prelim test: 137 Number of HSP's that attempted gapping in prelim test: 4042 Number of HSP's gapped (non-prelim): 741 length of query: 700 length of database: 10,336,785 effective HSP length: 104 effective length of query: 596 effective length of database: 6,526,121 effective search space: 3889568116 effective search space used: 3889568116 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 63 (28.8 bits)