BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q06892 (414 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3AFO-A nrPDB 796 0.0 3PFN-A nrPDB 152 3e-37 4HAO-A nrPDB 127 1e-29 2AN1-A nrPDB 120 2e-27 1U0T-A nrPDB 87 1e-17 1YT5-A nrPDB 87 2e-17 1SUW-A nrPDB 77 1e-14 1Z0S-A nrPDB 77 2e-14 3V8N-A nrPDB 55 6e-08 4OBV-D nrPDB 32 0.39 3T5P-A nrPDB 32 0.40 2ZWS-A nrPDB 30 1.6 4IYL-A nrPDB 30 2.7 2HMC-A nrPDB 29 2.9 4TW5-A nrPDB 29 3.1 6CDD-A nrPDB 29 3.3 5D98-B nrPDB 29 3.5 6HIX-Ag nrPDB 29 4.1 6CHS-A nrPDB 28 4.9 3SLI-A nrPDB 28 8.8 1XLT-A nrPDB 28 9.8 >3AFO-A nrPDB Length = 388 Score = 796 bits (2055), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/388 (100%), Positives = 388/388 (100%) Query: 27 LQSGSKFVKIKPVNNLRSSSSADFVSPPNSKLQSLIWQNPLQNVYITKKPWTPSTREAMV 86 LQSGSKFVKIKPVNNLRSSSSADFVSPPNSKLQSLIWQNPLQNVYITKKPWTPSTREAMV Sbjct: 1 LQSGSKFVKIKPVNNLRSSSSADFVSPPNSKLQSLIWQNPLQNVYITKKPWTPSTREAMV 60 Query: 87 EFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVT 146 EFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVT Sbjct: 61 EFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVT 120 Query: 147 LGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTR 206 LGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTR Sbjct: 121 LGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTR 180 Query: 207 LECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGS 266 LECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGS Sbjct: 181 LECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGS 240 Query: 267 TAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVK 326 TAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVK Sbjct: 241 TAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVK 300 Query: 327 LSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKT 386 LSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKT Sbjct: 301 LSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKT 360 Query: 387 ENDWIRGINELLGFNSSFRLTKRQTDND 414 ENDWIRGINELLGFNSSFRLTKRQTDND Sbjct: 361 ENDWIRGINELLGFNSSFRLTKRQTDND 388 >3PFN-A nrPDB Length = 365 Score = 152 bits (384), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 103/316 (32%), Positives = 164/316 (51%), Gaps = 42/316 (13%) Query: 59 QSLIWQNPLQNVYITKKPWTPSTREAMVEFITHLHES----YPEVNVIVQPDVAEEISQD 114 Q L W ++V + KK S + E THL E Y E V+ P +A + + Sbjct: 30 QRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIASD--ES 87 Query: 115 FKSPLENDPNRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALG 174 F + + + DI N+ D ++ LGGDGT+L+ S+F + VPPV+AF LG Sbjct: 88 FGAV-----KKKFCTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGS-VPPVMAFHLG 141 Query: 175 TLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTH----------- 223 +LGFL+PF F+ + +VI A + R+RL+ + K+ H Sbjct: 142 SLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKELRGKKTAVHNGLGEKGSQAA 201 Query: 224 --------------AMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGSTAY 269 +N++ + RG S +L+N+D+++DG +T DGV ++TPTGSTAY Sbjct: 202 GLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAY 261 Query: 270 SLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVKLSV 329 + +AG S++ P VPAI++TPICP SLSFRP+++P ++I + + + +S Sbjct: 262 AAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPE-----ARNTAWVSF 316 Query: 330 DGIPQQDLDVGDEIYV 345 DG +Q++ GD I + Sbjct: 317 DGRKRQEIRHGDSISI 332 >4HAO-A nrPDB Length = 304 Score = 127 bits (318), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 73/215 (33%), Positives = 116/215 (53%), Gaps = 8/215 (3%) Query: 131 TGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKV 190 TG DI + DL V +GGDG +L + + V+ G LGFL+ D + Sbjct: 55 TGSLADIGQKADLAVVVGGDGNMLGAARVLARYDIK-VIGVNRGNLGFLTDLDPDNALQQ 113 Query: 191 FQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFL 250 +V+ R LE H+++ + S I T A+N++ LH G H+ +++ID F Sbjct: 114 LSDVLEGEYLSEQRFLLETHVRRTNQQSRIST-AINEVVLHPGKVAHMIEFEVYIDDRFA 172 Query: 251 TRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRI 310 +DG+ +ATPTGSTAYSLSAGG I++P + AI++ P+ P +L+ RPL++ SS IR+ Sbjct: 173 FSQRSDGLIIATPTGSTAYSLSAGGPILTPTLDAIVLVPMFPHTLTARPLVISSSSTIRL 232 Query: 311 KIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYV 345 K + S +++S D + G+E+ + Sbjct: 233 KFSH------ITSDLEISCDSQIALPIQEGEEVLI 261 >2AN1-A nrPDB Length = 292 Score = 120 bits (300), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 74/215 (34%), Positives = 113/215 (52%), Gaps = 15/215 (6%) Query: 101 VIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMF 160 VIV+ +A E+ L+N P TG +I + DL V +GGDG +L Sbjct: 37 VIVEQQIAHELQ------LKNVP-------TGTLAEIGQQADLAVVVGGDGNMLGAARTL 83 Query: 161 GNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSI 220 + V+ G LGFL+ D + +V+ R R LE + ++D I Sbjct: 84 ARYDIN-VIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRI 142 Query: 221 VTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGSTAYSLSAGGSIVSP 280 T A+N++ LH G H+ +++ID F +DG+ ++TPTGSTAYSLSAGG I++P Sbjct: 143 ST-AINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTP 201 Query: 281 LVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSK 315 + AI + P+ P +LS RPL++ SS IR++ + Sbjct: 202 SLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHR 236 >1U0T-A nrPDB Length = 307 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 57/181 (31%), Positives = 97/181 (53%), Gaps = 6/181 (3%) Query: 134 EQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQE 193 +Q + +L++ LGGDGT L + N +P VL LG +GFL+ + + V + Sbjct: 69 DQHAADGCELVLVLGGDGTFLRAAELARNASIP-VLGVNLGRIGFLAEAEAEAIDAVLEH 127 Query: 194 VISSRAKCLHRTRLECHLKKKDSNSSIVTH--AMNDIFLHRGNSPHLTNLDIFIDGEFLT 251 V++ + R L+ +++ IV A+N++ L +G + + + IDG ++ Sbjct: 128 VVAQDYRVEDRLTLDVVVRQ---GGRIVNRGWALNEVSLEKGPRLGVLGVVVEIDGRPVS 184 Query: 252 RTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIK 311 DGV ++TPTGSTAY+ SAGG ++ P + AIL+ P +L RP++ + I I+ Sbjct: 185 AFGCDGVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEATIAIE 244 Query: 312 I 312 I Sbjct: 245 I 245 >1YT5-A nrPDB Length = 258 Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 55/192 (28%), Positives = 99/192 (51%), Gaps = 17/192 (8%) Query: 141 TDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAK 200 DL+V +GGDGT+L + P++ F G LGFL+ + E + +++ + + Sbjct: 42 ADLIVVVGGDGTVLKAAKKAADGT--PMVGFKAGRLGFLTSYTLDEIDRFLEDLRNWNFR 99 Query: 201 CLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVAL 260 TR ++ + N A+ND+ L R S + +++ ++ ADGV + Sbjct: 100 --EETRWFIQIESELGNH----LALNDVTLERDLSGKMVEIEVEVEHHSSMWFFADGVVI 153 Query: 261 ATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKP 320 +TPTGSTAYSLS GG I+ P + ++PI P+ R +++P + + ++ +Q+ Sbjct: 154 STPTGSTAYSLSIGGPIIFPECEVLEISPIAPQFFLTRSVVIPSNFKVVVE-----SQRD 208 Query: 321 VNSVVKLSVDGI 332 +N + VDG+ Sbjct: 209 IN----MLVDGV 216 >1SUW-A nrPDB Length = 249 Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 64/248 (25%), Positives = 107/248 (43%), Gaps = 41/248 (16%) Query: 129 LYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFL---SPFDFK 185 L+ P +++ N D +V++GGDGTIL + + PP+ G +G L SP +F+ Sbjct: 29 LFNQPSEELEN-FDFIVSVGGDGTILRILQKL--KRCPPIFGINTGRVGLLTHASPENFE 85 Query: 186 -EHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIF 244 E KK ++ R R+ C A+N+I + + ++ + Sbjct: 86 VELKKAVEKFEVERF-----PRVSCSAMPD-------VLALNEIAVLSRKPAKMIDVALR 133 Query: 245 IDGEFLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPH 304 +DG + R DG +AT GST Y+ SAGG +V P + ++ PI P ++P ++ Sbjct: 134 VDGVEVDRIRCDGFIVATQIGSTGYAFSAGGPVVEPYLECFILIPIAPFRFGWKPYVVSM 193 Query: 305 SSHIRIKIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTT-R 363 I + + +K + + DG D D G I I+ ++ P Sbjct: 194 ERKIEV-----IAEKAI-----VVADGQKSVDFD-----------GEITIEKSEFPAVFF 232 Query: 364 KTENDFNN 371 K E F N Sbjct: 233 KNEKRFRN 240 >1Z0S-A nrPDB Length = 278 Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/248 (25%), Positives = 107/248 (43%), Gaps = 41/248 (16%) Query: 129 LYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFL---SPFDFK 185 L+ P +++ N D +V++GGDGTIL + + PP+ G +G L SP +F+ Sbjct: 58 LFNQPSEELEN-FDFIVSVGGDGTILRILQKL--KRCPPIFGINTGRVGLLTHASPENFE 114 Query: 186 -EHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIF 244 E KK ++ R R+ C A+N+I + + ++ + Sbjct: 115 VELKKAVEKFEVERF-----PRVSCSAMPD-------VLALNEIAVLSRKPAKMIDVALR 162 Query: 245 IDGEFLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPH 304 +DG + R DG +AT GST Y+ SAGG +V P + ++ PI P ++P ++ Sbjct: 163 VDGVEVDRIRCDGFIVATQIGSTGYAFSAGGPVVEPYLECFILIPIAPFRFGWKPYVVSM 222 Query: 305 SSHIRIKIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTT-R 363 I + + +K + + DG D D G I I+ ++ P Sbjct: 223 ERKIEV-----IAEKAI-----VVADGQKSVDFD-----------GEITIEKSEFPAVFF 261 Query: 364 KTENDFNN 371 K E F N Sbjct: 262 KNEKRFRN 269 >3V8N-A nrPDB Length = 272 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 51/236 (21%), Positives = 104/236 (44%), Gaps = 19/236 (8%) Query: 142 DLLVTLGGDGTILHGVSMFGNT-QVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAK 200 ++++++GGDGT L + + G LGF + + E K+ + + + Sbjct: 37 EIVISIGGDGTFLSAFHQYEERLDEIAFIGIHTGHLGFYADWRPAEADKLVKLLAKGEYQ 96 Query: 201 CLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVAL 260 + L+ +K A+N+ + P + +D+ I+ R DG+ + Sbjct: 97 KVSYPLLKTTVKYGIGKKEATYLALNESTVKSSGGPFV--VDVVINDIHFERFRGDGLCM 154 Query: 261 ATPTGSTAYSLSAGGSIVSPLVPAILMTPICP------RSLSFRPLILPHSSHIRIKIGS 314 +TP+G+TAY+ S GG+++ P + A+ +T + R++ PL+ P H+ Sbjct: 155 STPSGTTAYNKSLGGALMHPSIEAMQLTEMASINNRVYRTIG-SPLVFP-KHHV------ 206 Query: 315 KLNQKPVNSV-VKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDF 369 ++ +PVN ++SVD + DV + Y ++ + P R+ + F Sbjct: 207 -VSLQPVNDKDFQISVDHLSILHRDVQEIRYEVSAKKIHFARFRSFPFWRRVHDSF 261 >4OBV-D nrPDB Length = 490 Score = 32.3 bits (72), Expect = 0.39, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 7/68 (10%) Query: 218 SSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGSTAYSLSAGGSI 277 + +V+ MN+++ +RG++ H F+ G A V+ ++AY++ AGGS Sbjct: 73 NEVVSEMMNEVYRYRGDANHPRFFS-FVPG------PASSVSWLGDIMTSAYNIHAGGSK 125 Query: 278 VSPLVPAI 285 ++P+V I Sbjct: 126 LAPMVNCI 133 >3T5P-A nrPDB Length = 306 Score = 32.3 bits (72), Expect = 0.40, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 7/55 (12%) Query: 127 HILYTGPE-------QDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALG 174 HIL+T + Q+ ++ DL++ GGDGT+ + ++ P LA G Sbjct: 47 HILHTKEQGDATKYCQEFASKVDLIIVFGGDGTVFECTNGLAPLEIRPTLAIIPG 101 >2ZWS-A nrPDB Length = 646 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 33/139 (23%), Positives = 56/139 (40%), Gaps = 30/139 (21%) Query: 295 LSFRPLILPHSSHIRIKIGSKLNQ-----KPVNSVVKLSVDGIPQQDLDVGDEIYVINEV 349 ++F+ ++ +I G L Q + + V V G P+ DL ++ ++ EV Sbjct: 506 MNFQTGVVADDPYIGKSFGDVLQQPRESYRIGDKVTVAFVTGHPKNDLRT-EKTFL--EV 562 Query: 350 GTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKT----------------------E 387 I DG Q P T T+ND++ + +R GI T + Sbjct: 563 VNIGKDGKQTPVTVATDNDWDTQYRWERVGISASKATISWSIPPGTEPGHYYIRHYGNAK 622 Query: 388 NDWIRGINELLGFNSSFRL 406 N W + I+E+ G SF + Sbjct: 623 NFWTQKISEIGGSTRSFEV 641 >4IYL-A nrPDB Length = 93 Score = 29.6 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 4/40 (10%) Query: 183 DFKEHKKVFQEVISSRAKCL----HRTRLECHLKKKDSNS 218 + EH K++++ SSR L R RL +LK+KD NS Sbjct: 41 ELTEHLKIYKKDFSSRLGLLKLVGQRKRLLSYLKRKDYNS 80 >2HMC-A nrPDB Length = 344 Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 19/48 (39%) Query: 115 FKSPLENDPNRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGN 162 FK+ L P P ++Y P R DL L + L G FG Sbjct: 142 FKAILSAAPEIPAVIYNSPYYGFATRADLFFALRAEHKNLVGFKEFGG 189 >4TW5-A nrPDB Length = 272 Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 7/79 (8%) Query: 71 YITKKPWTPSTREAMVEFITHLHESYPEVNVIVQPDVAEEISQ-----DFKSPLENDPNR 125 YI TP T+E+++ F ES N+ D A+ SQ DF + R Sbjct: 96 YIKSFTETPRTKESLIAFARR--ESMDPNNLDTDLDSAKSESQYLEGFDFLELIAGKATR 153 Query: 126 PHILYTGPEQDIVNRTDLL 144 PH++ P +D+ N D L Sbjct: 154 PHLVSFWPTKDMKNSDDSL 172 >6CDD-A nrPDB Length = 474 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Query: 99 VNVIVQPDVAEEISQDFKSPLENDPNRPHIL-YTGPEQDIVNRTDLLVTLGGDGTIL--- 154 V I +P +EI +P EN+ + Y G EQ V TDLL GDG+++ Sbjct: 176 VEAIYEPPQVDEIDGITLNPWENEQEVNQVAKYCGLEQVGVIWTDLLDAGKGDGSVVCKR 235 Query: 155 HGVSMFGNTQ 164 H S F Q Sbjct: 236 HADSYFLAAQ 245 >5D98-B nrPDB Length = 754 Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust. Identities = 39/154 (25%), Positives = 62/154 (40%), Gaps = 19/154 (12%) Query: 233 GNSPHLTNL-DIFIDGEFLTRTTADGVALATPTGSTAYSLSAGGSIV------SPLVP-- 283 G+ P L +F DGEF++ + A T + +A SI+ + L P Sbjct: 485 GSLPELFEFTSMFFDGEFVSNLAMELPAFTTAGVNEGVDFTAAMSIIKTNMINNSLSPST 544 Query: 284 AILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVKLSVDGIPQQD-LDVGDE 342 A++ IC + FR H R+K G K +N +K I +D L + D Sbjct: 545 ALMALRICLQ--EFRATYRVHPWDSRVKGG---RMKIINEFIKT----IENKDGLLIADG 595 Query: 343 IYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPK 376 ++N + T++I L + E N PK Sbjct: 596 GKLMNNISTLHIPEEVLKFEKMDEQYRNRVFNPK 629 >6HIX-Ag nrPDB Length = 260 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 10/35 (28%), Positives = 21/35 (60%) Query: 78 TPSTREAMVEFITHLHESYPEVNVIVQPDVAEEIS 112 P+TR+ + + H H YP V++ ++P + E++ Sbjct: 22 APNTRQFLATHLPHFHAKYPSVSIDLRPRLWPEMA 56 >6CHS-A nrPDB Length = 659 Score = 28.5 bits (62), Expect = 4.9, Method: Compositional matrix adjust. Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Query: 99 VNVIVQPDVAEEISQDFKSPLENDPNRPHIL-YTGPEQDIVNRTDLLVTLGGDGTIL--- 154 V I +P +EI +P EN+ + Y G EQ V TDLL GDG+++ Sbjct: 304 VEAIYEPPQVDEIDGITLNPWENEQEVNQVAKYCGLEQVGVIWTDLLDAGKGDGSVVCKR 363 Query: 155 HGVSMFGNTQ 164 H S F Q Sbjct: 364 HADSYFLAAQ 373 >3SLI-A nrPDB Length = 679 Score = 27.7 bits (60), Expect = 8.8, Method: Compositional matrix adjust. Identities = 22/93 (23%), Positives = 34/93 (36%), Gaps = 5/93 (5%) Query: 278 VSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVKLSVDGIPQQDL 337 S + P +L + R F L+ +GS + +KL + Sbjct: 291 ASYIDPVLLEDKLTKRIFLFADLMPAGIGSSNASVGSGFKEVNGKKYLKLRWHKDAGRAY 350 Query: 338 DVGDEIYVINEVGTIYIDGTQLPTTRKTENDFN 370 D Y I E G IY D T PT + + ++N Sbjct: 351 D-----YTIREKGVIYNDATNQPTEFRVDGEYN 378 >1XLT-A nrPDB Length = 384 Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust. Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 20/81 (24%) Query: 142 DLLVTLGGD------GTIL--HGVSMFGNTQVPPVLA------FALGTLGFLSPFDFKEH 187 DL V GG+ G I+ HGV + G+T VP +A FA L FL+P K+ Sbjct: 292 DLAVEAGGNCPLSEPGKIVVKHGVKIVGHTNVPSRVAADASPLFAKNLLNFLTPHVDKDT 351 Query: 188 K----KVFQEVISSRAKCLHR 204 K K+ E +S C+ R Sbjct: 352 KTLVMKLEDETVSG--TCVTR 370 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3AFO-A nrPDB 600 e-172 3PFN-A nrPDB 310 9e-85 2AN1-A nrPDB 275 2e-74 4HAO-A nrPDB 266 2e-71 3V8N-A nrPDB 245 3e-65 1Z0S-A nrPDB 223 1e-58 1SUW-A nrPDB 223 1e-58 1U0T-A nrPDB 211 3e-55 1YT5-A nrPDB 206 2e-53 Sequences not found previously or not previously below threshold: 4KR6-A nrPDB 38 0.009 4WER-A nrPDB 35 0.049 6HIV-CJ nrPDB 34 0.11 3T5P-A nrPDB 34 0.14 2QBU-A nrPDB 33 0.24 5MRF-P nrPDB 31 0.92 1SDD-A nrPDB 31 1.0 3J6B-P nrPDB 31 1.0 4UEJ-A nrPDB 29 2.9 1ZXX-A nrPDB 29 3.6 3P53-A nrPDB 29 4.0 1T6G-A nrPDB 29 4.2 4NNZ-A nrPDB 29 4.7 2NVO-A nrPDB 29 4.7 3IU0-A nrPDB 29 5.4 5G04-F nrPDB 28 7.0 2ZTN-A nrPDB 28 7.5 CONVERGED! >3AFO-A nrPDB Length = 388 Score = 600 bits (1547), Expect = e-172, Method: Composition-based stats. Identities = 388/388 (100%), Positives = 388/388 (100%) Query: 27 LQSGSKFVKIKPVNNLRSSSSADFVSPPNSKLQSLIWQNPLQNVYITKKPWTPSTREAMV 86 LQSGSKFVKIKPVNNLRSSSSADFVSPPNSKLQSLIWQNPLQNVYITKKPWTPSTREAMV Sbjct: 1 LQSGSKFVKIKPVNNLRSSSSADFVSPPNSKLQSLIWQNPLQNVYITKKPWTPSTREAMV 60 Query: 87 EFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVT 146 EFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVT Sbjct: 61 EFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVT 120 Query: 147 LGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTR 206 LGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTR Sbjct: 121 LGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTR 180 Query: 207 LECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGS 266 LECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGS Sbjct: 181 LECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGS 240 Query: 267 TAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVK 326 TAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVK Sbjct: 241 TAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVK 300 Query: 327 LSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKT 386 LSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKT Sbjct: 301 LSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKT 360 Query: 387 ENDWIRGINELLGFNSSFRLTKRQTDND 414 ENDWIRGINELLGFNSSFRLTKRQTDND Sbjct: 361 ENDWIRGINELLGFNSSFRLTKRQTDND 388 >3PFN-A nrPDB Length = 365 Score = 310 bits (793), Expect = 9e-85, Method: Composition-based stats. Identities = 103/319 (32%), Positives = 163/319 (51%), Gaps = 42/319 (13%) Query: 59 QSLIWQNPLQNVYITKKPWTPSTREAMVEFITHLHES----YPEVNVIVQPDVAEEISQD 114 Q L W ++V + KK S + E THL E Y E V+ P +A + + Sbjct: 30 QRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIASD--ES 87 Query: 115 FKSPLENDPNRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALG 174 F + + + DI N+ D ++ LGGDGT+L+ S+F VPPV+AF LG Sbjct: 88 FGAV-----KKKFCTFREDYDDISNQIDFIICLGGDGTLLYASSLFQG-SVPPVMAFHLG 141 Query: 175 TLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTH----------- 223 +LGFL+PF F+ + +VI A + R+RL+ + K+ H Sbjct: 142 SLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKELRGKKTAVHNGLGEKGSQAA 201 Query: 224 --------------AMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGSTAY 269 +N++ + RG S +L+N+D+++DG +T DGV ++TPTGSTAY Sbjct: 202 GLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAY 261 Query: 270 SLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVKLSV 329 + +AG S++ P VPAI++TPICP SLSFRP+++P ++I + + + +S Sbjct: 262 AAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPE-----ARNTAWVSF 316 Query: 330 DGIPQQDLDVGDEIYVINE 348 DG +Q++ GD I + Sbjct: 317 DGRKRQEIRHGDSISITTS 335 >2AN1-A nrPDB Length = 292 Score = 275 bits (704), Expect = 2e-74, Method: Composition-based stats. Identities = 84/282 (29%), Positives = 135/282 (47%), Gaps = 23/282 (8%) Query: 64 QNPLQNVYITKKPWTPSTREAMVEFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDP 123 N + + I P P+ L + E VIV+ +A E+ L+N P Sbjct: 2 NNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYE--VIVEQQIAHELQ------LKNVP 53 Query: 124 NRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFD 183 TG +I + DL V +GGDG +L + V+ G LGFL+ D Sbjct: 54 -------TGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDIN-VIGINRGNLGFLTDLD 105 Query: 184 FKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDI 243 + +V+ R R LE + ++D I T A+N++ LH G H+ ++ Sbjct: 106 PDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRIST-AINEVVLHPGKVAHMIEFEV 164 Query: 244 FIDGEFLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILP 303 +ID F +DG+ ++TPTGSTAYSLSAGG I++P + AI + P+ P +LS RPL++ Sbjct: 165 YIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIN 224 Query: 304 HSSHIRIKIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYV 345 SS IR++ + S +++S D + G+++ + Sbjct: 225 SSSTIRLRFSHR------RSDLEISCDSQIALPIQEGEDVLI 260 >4HAO-A nrPDB Length = 304 Score = 266 bits (679), Expect = 2e-71, Method: Composition-based stats. Identities = 82/274 (29%), Positives = 135/274 (49%), Gaps = 23/274 (8%) Query: 72 ITKKPWTPSTREAMVEFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYT 131 I P P+ A E + H ++ V+V+ +A +++ T Sbjct: 11 IVGHPRHPAAL-ATHEILYHWLKAR-GYAVMVEQQIAHDLNLTDA-------------IT 55 Query: 132 GPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVF 191 G DI + DL V +GGDG +L + + V+ G LGFL+ D + Sbjct: 56 GSLADIGQKADLAVVVGGDGNMLGAARVLARYDIK-VIGVNRGNLGFLTDLDPDNALQQL 114 Query: 192 QEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLT 251 +V+ R LE H+++ + S I T A+N++ LH G H+ +++ID F Sbjct: 115 SDVLEGEYLSEQRFLLETHVRRTNQQSRIST-AINEVVLHPGKVAHMIEFEVYIDDRFAF 173 Query: 252 RTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIK 311 +DG+ +ATPTGSTAYSLSAGG I++P + AI++ P+ P +L+ RPL++ SS IR+K Sbjct: 174 SQRSDGLIIATPTGSTAYSLSAGGPILTPTLDAIVLVPMFPHTLTARPLVISSSSTIRLK 233 Query: 312 IGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYV 345 + S +++S D + G+E+ + Sbjct: 234 FSH------ITSDLEISCDSQIALPIQEGEEVLI 261 >3V8N-A nrPDB Length = 272 Score = 245 bits (625), Expect = 3e-65, Method: Composition-based stats. Identities = 52/250 (20%), Positives = 104/250 (41%), Gaps = 19/250 (7%) Query: 127 HILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNT-QVPPVLAFALGTLGFLSPFDFK 185 Y D+ ++++++GGDGT L + + G LGF + + Sbjct: 24 FGEYDMEYDDVE--PEIVISIGGDGTFLSAFHQYEERLDEIAFIGIHTGHLGFYADWRPA 81 Query: 186 EHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFI 245 E K+ + + + + L+ +K A+N+ + P + +D+ I Sbjct: 82 EADKLVKLLAKGEYQKVSYPLLKTTVKYGIGKKEATYLALNESTVKSSGGPFV--VDVVI 139 Query: 246 DGEFLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICP-----RSLSFRPL 300 + R DG+ ++TP+G+TAY+ S GG+++ P + A+ +T + PL Sbjct: 140 NDIHFERFRGDGLCMSTPSGTTAYNKSLGGALMHPSIEAMQLTEMASINNRVYRTIGSPL 199 Query: 301 ILPHSSHIRIKIGSKLNQKPVNS-VVKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQL 359 + P H+ ++ +PVN ++SVD + DV + Y ++ + Sbjct: 200 VFP-KHHV-------VSLQPVNDKDFQISVDHLSILHRDVQEIRYEVSAKKIHFARFRSF 251 Query: 360 PTTRKTENDF 369 P R+ + F Sbjct: 252 PFWRRVHDSF 261 >1Z0S-A nrPDB Length = 278 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 56/244 (22%), Positives = 101/244 (41%), Gaps = 33/244 (13%) Query: 129 LYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHK 188 L+ P +++ N D +V++GGDGTIL + + PP+ G +G L+ + + Sbjct: 58 LFNQPSEELEN-FDFIVSVGGDGTILRILQKL--KRCPPIFGINTGRVGLLTHASPENFE 114 Query: 189 KVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGE 248 ++ + + + R+ C A+N+I + + ++ + +DG Sbjct: 115 VELKKAVE-KFEVERFPRVSCSAMPD-------VLALNEIAVLSRKPAKMIDVALRVDGV 166 Query: 249 FLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHI 308 + R DG +AT GST Y+ SAGG +V P + ++ PI P ++P ++ I Sbjct: 167 EVDRIRCDGFIVATQIGSTGYAFSAGGPVVEPYLECFILIPIAPFRFGWKPYVVSMERKI 226 Query: 309 RIKIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTT-RKTEN 367 + + + DG D D G I I+ ++ P K E Sbjct: 227 EV----------IAEKAIVVADGQKSVDFD-----------GEITIEKSEFPAVFFKNEK 265 Query: 368 DFNN 371 F N Sbjct: 266 RFRN 269 >1SUW-A nrPDB Length = 249 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 56/244 (22%), Positives = 101/244 (41%), Gaps = 33/244 (13%) Query: 129 LYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHK 188 L+ P +++ N D +V++GGDGTIL + + PP+ G +G L+ + + Sbjct: 29 LFNQPSEELEN-FDFIVSVGGDGTILRILQKL--KRCPPIFGINTGRVGLLTHASPENFE 85 Query: 189 KVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGE 248 ++ + + + R+ C A+N+I + + ++ + +DG Sbjct: 86 VELKKAVE-KFEVERFPRVSCSAMPD-------VLALNEIAVLSRKPAKMIDVALRVDGV 137 Query: 249 FLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHI 308 + R DG +AT GST Y+ SAGG +V P + ++ PI P ++P ++ I Sbjct: 138 EVDRIRCDGFIVATQIGSTGYAFSAGGPVVEPYLECFILIPIAPFRFGWKPYVVSMERKI 197 Query: 309 RIKIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTT-RKTEN 367 + + + DG D D G I I+ ++ P K E Sbjct: 198 EV----------IAEKAIVVADGQKSVDFD-----------GEITIEKSEFPAVFFKNEK 236 Query: 368 DFNN 371 F N Sbjct: 237 RFRN 240 >1U0T-A nrPDB Length = 307 Score = 211 bits (538), Expect = 3e-55, Method: Composition-based stats. Identities = 65/240 (27%), Positives = 114/240 (47%), Gaps = 13/240 (5%) Query: 134 EQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQE 193 +Q + +L++ LGGDGT L + N + PVL LG +GFL+ + + V + Sbjct: 69 DQHAADGCELVLVLGGDGTFLRAAELARNASI-PVLGVNLGRIGFLAEAEAEAIDAVLEH 127 Query: 194 VISSRAKCLHRTRLECHLKKKDSNSSIVTH--AMNDIFLHRGNSPHLTNLDIFIDGEFLT 251 V++ + R L+ +++ IV A+N++ L +G + + + IDG ++ Sbjct: 128 VVAQDYRVEDRLTLDVVVRQ---GGRIVNRGWALNEVSLEKGPRLGVLGVVVEIDGRPVS 184 Query: 252 RTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIK 311 DGV ++TPTGSTAY+ SAGG ++ P + AIL+ P +L RP++ + I I+ Sbjct: 185 AFGCDGVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEATIAIE 244 Query: 312 IGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYVINEVGTI-YIDGTQLPTTRKTENDFN 370 I + + DG + + G + V V ++ + P T + F Sbjct: 245 IEAD------GHDALVFCDGRREMLIPAGSRLEVTRCVTSVKWARLDSAPFTDRLVRKFR 298 >1YT5-A nrPDB Length = 258 Score = 206 bits (524), Expect = 2e-53, Method: Composition-based stats. Identities = 59/225 (26%), Positives = 108/225 (48%), Gaps = 19/225 (8%) Query: 110 EISQDFKSPLENDPNRPH--ILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPP 167 E + L+ ++ H I + DL+V +GGDGT+L + P Sbjct: 9 EEREKEGEFLKEKISKEHEVIEFGEANAPGRVTADLIVVVGGDGTVLKAAKKAADGT--P 66 Query: 168 VLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMND 227 ++ F G LGFL+ + E + +++ + + TR ++ + N A+ND Sbjct: 67 MVGFKAGRLGFLTSYTLDEIDRFLEDLRNWNFR--EETRWFIQIESELGNH----LALND 120 Query: 228 IFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILM 287 + L R S + +++ ++ ADGV ++TPTGSTAYSLS GG I+ P + + Sbjct: 121 VTLERDLSGKMVEIEVEVEHHSSMWFFADGVVISTPTGSTAYSLSIGGPIIFPECEVLEI 180 Query: 288 TPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVKLSVDGI 332 +PI P+ R +++P + + ++ +Q+ +N + VDG+ Sbjct: 181 SPIAPQFFLTRSVVIPSNFKVVVE-----SQRDIN----MLVDGV 216 >4KR6-A nrPDB Length = 388 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 24/182 (13%), Positives = 64/182 (35%), Gaps = 27/182 (14%) Query: 162 NTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIV 221 + ++ + + GFL DF+E KK + + + + + KK Sbjct: 58 DDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKG 117 Query: 222 THAMN------------DIFLHRGNSPHLTNLDIFIDGEFLTRTTAD---GVALATPTGS 266 + +N ++ + N + +++ +G + + G+ + T G Sbjct: 118 VYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGT--GG 175 Query: 267 TAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVK 326 A L +GG + +P+ R +++ + + S+ + V +++ Sbjct: 176 KAVLLLSGG----------IDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILR 225 Query: 327 LS 328 + Sbjct: 226 VL 227 >4WER-A nrPDB Length = 303 Score = 35.1 bits (79), Expect = 0.049, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 34/90 (37%), Gaps = 6/90 (6%) Query: 109 EEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPV 168 E++ Q F + + + + D + +GGDGT+ G+S P Sbjct: 29 EKLKQLFDEVVVKQTEKGGDAEQFAREAAESHFDSVFVMGGDGTVNEGISGLAEQAYRPK 88 Query: 169 LA-FALGTLGFLS-----PFDFKEHKKVFQ 192 F LGT+ L+ P D +E + Sbjct: 89 FGFFPLGTVNDLARALNLPMDPEEAIQQLD 118 >6HIV-CJ nrPDB Length = 817 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 24/59 (40%) Query: 335 QDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKTENDWIRG 393 DVG + + G I D + P KTE+ + R+ + TE D IRG Sbjct: 182 VQRDVGRLEPIPSYAGKINADRSVFPFQWKTEDWYEYEVAKVRNRRFVFENTEEDGIRG 240 >3T5P-A nrPDB Length = 306 Score = 34.0 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 25/128 (19%), Positives = 46/128 (35%), Gaps = 14/128 (10%) Query: 135 QDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEV 194 Q+ ++ DL++ GGDGT+ + ++ P LA G G + F Sbjct: 62 QEFASKVDLIIVFGGDGTVFECTNGLAPLEIRPTLAIIPG--GTCNDFSR-------TLG 112 Query: 195 ISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTT 254 + + + H+K D + H +N ++ + ID E + Sbjct: 113 VPQNIAEAAKLITKEHVKPVDVAKANGQHFLN-----FWGIGLVSEVSNNIDAEEKAKLG 167 Query: 255 ADGVALAT 262 G L+T Sbjct: 168 KIGYYLST 175 >2QBU-A nrPDB Length = 232 Score = 33.2 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 39/221 (17%), Positives = 71/221 (32%), Gaps = 27/221 (12%) Query: 51 VSPPNSKLQSLIWQNPLQNVYITKKPWTPSTREAMVEFITHLHESYPEVNVIVQPDVAEE 110 V P +S+L +L N L++V + P + S RE+ + S E + + D Sbjct: 10 VGPGDSELLTLRAVNVLRSVPVICAPRSSSERES-------IALSIVEDILTERRDGCRI 62 Query: 111 ISQDFKSPLENDPNRPH--ILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPV 168 + F + D H ++ + D+ GD +I S Sbjct: 63 LDPVFPMTDDRDELESHWDSAARMVAAELEDGRDVAFITLGDPSIYSTFSYLQQRIED-- 120 Query: 169 LAFALGTLGFLSPFDF------------KEHKKVFQEVISSRAKCLHRTRLECHLKKKDS 216 + F + ++ F E V V R + + R C + K Sbjct: 121 MGFKTEMVPGVTSFTACAATAGRTLVEGDEILLVVPRV-DDRFERVLRDVDACVIMKTSR 179 Query: 217 NSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADG 257 + AM + ++ + +D E + R A G Sbjct: 180 HGR---RAMEVVESDPRGKDVVSVANCSMDDEVVERGFASG 217 >5MRF-P nrPDB Length = 207 Score = 30.9 bits (68), Expect = 0.92, Method: Composition-based stats. Identities = 29/159 (18%), Positives = 53/159 (33%), Gaps = 21/159 (13%) Query: 274 GGSIVSPLVPAILMTPICPRSLSFRPLILPHSSH---IRIKIGSKLNQKPVNSVVKLSVD 330 G + P IL+ P + I+P S + +R + + +N +L Sbjct: 27 GNKVYFPKARIILLRPNAKHTPYQAKFIVPKSFNKLDLRDYLYHIYGLRAMNITTQLL-- 84 Query: 331 GIPQQDLDVGDEIYVINEVGTIYIDGTQLPTT----RKTENDFNNSKKPKRSGIY----- 381 +++ + ++ + I+ + R EN F +S P Y Sbjct: 85 HGKFNRMNLQTTRFREPQIKKMTIEMEEPFIWPEEPRPDENSFWDSTTPDNMEKYREERL 144 Query: 382 -CVAKTEN------DWIRGINELLGFNSSFRLTKRQTDN 413 C+ N D + G E + R KR+ DN Sbjct: 145 NCLGSDANKPGTAFDGVVGPYERVAQPFIPRFLKREIDN 183 >1SDD-A nrPDB Length = 306 Score = 30.9 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 35/77 (45%), Gaps = 3/77 (3%) Query: 59 QSLIWQNPLQNVYITKKPWTPSTRE-AMVEFITHLHESYPEVNV--IVQPDVAEEISQDF 115 QS+ W ++ +++ KP+ S ++ E+ + + P+ ++ P + E+ Sbjct: 11 QSIRWNYRPESTHLSSKPFETSFKKIVYREYEAYFQKEKPQSRTSGLLGPTLYAEVGDIM 70 Query: 116 KSPLENDPNRPHILYTG 132 K +N ++P ++ Sbjct: 71 KVHFKNKAHKPLSIHAQ 87 >3J6B-P nrPDB Length = 263 Score = 30.9 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 29/159 (18%), Positives = 53/159 (33%), Gaps = 21/159 (13%) Query: 274 GGSIVSPLVPAILMTPICPRSLSFRPLILPHSSH---IRIKIGSKLNQKPVNSVVKLSVD 330 G + P IL+ P + I+P S + +R + + +N +L Sbjct: 81 GNKVYFPKARIILLRPNAKHTPYQAKFIVPKSFNKLDLRDYLYHIYGLRAMNITTQLL-- 138 Query: 331 GIPQQDLDVGDEIYVINEVGTIYIDGTQLPTT----RKTENDFNNSKKPKRSGIY----- 381 +++ + ++ + I+ + R EN F +S P Y Sbjct: 139 HGKFNRMNLQTTRFREPQIKKMTIEMEEPFIWPEEPRPDENSFWDSTTPDNMEKYREERL 198 Query: 382 -CVAKTEN------DWIRGINELLGFNSSFRLTKRQTDN 413 C+ N D + G E + R KR+ DN Sbjct: 199 NCLGSDANKPGTAFDGVVGPYERVAQPFIPRFLKREIDN 237 >4UEJ-A nrPDB Length = 346 Score = 29.4 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 15/105 (14%), Positives = 31/105 (29%), Gaps = 8/105 (7%) Query: 154 LHGVSMFGNTQVPPVLAFALGTLGFLS--------PFDFKEHKKVFQEVISSRAKCLHRT 205 LH + + V+ GT+G L+ +++ +++ +T Sbjct: 150 LHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 Query: 206 RLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFL 250 + S + N + L P L + I G Sbjct: 210 FNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHA 254 >1ZXX-A nrPDB Length = 319 Score = 29.0 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 23/66 (34%), Gaps = 5/66 (7%) Query: 102 IVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVN----RTDLLVTLGGDGTILHGV 157 + DVA I+ + L + G I D +V +GGDG+ + Sbjct: 52 LESEDVAHLINVS-GTFLYSARYPEFAEEEGQLAGIEQLKKHGIDAVVVIGGDGSYHGAL 110 Query: 158 SMFGNT 163 + + Sbjct: 111 QLTRHG 116 >3P53-A nrPDB Length = 496 Score = 29.0 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 16/122 (13%), Positives = 36/122 (29%), Gaps = 9/122 (7%) Query: 180 SPFDFKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLT 239 + + ++ + + + + ++I + R + Sbjct: 118 TEDRLSCFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVD 177 Query: 240 NLDI--FIDGEFLTRT------TADGVALATPTGSTAYSLSA-GGSIVSPLVPAILMTPI 290 +L F D + +T DG +A P +T Y+L G + + P Sbjct: 178 SLITLAFQDQRYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPS 237 Query: 291 CP 292 P Sbjct: 238 GP 239 >1T6G-A nrPDB Length = 381 Score = 29.0 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 23/55 (41%), Gaps = 7/55 (12%) Query: 255 ADGVALATPTGSTAYSLSAGGSIVSPLV-PAILMTPIC------PRSLSFRPLIL 302 A+ L PTG ++ GG + P ++ TP+ +S R +++ Sbjct: 161 ANRFLLCLPTGGPGVAIFGGGPVPWPQFTQSMPYTPLVTKGGSPAHYISARSIVV 215 >4NNZ-A nrPDB Length = 439 Score = 28.6 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 25/155 (16%), Positives = 52/155 (33%), Gaps = 19/155 (12%) Query: 77 WTPSTREAMVEFITHLHESYPEVN----VIVQPDVAEEISQDFKSPLENDPNRPHILYTG 132 W + ++ + H +ES+ N V+V A+E+ K P R Sbjct: 165 WMADLQRMTIDDLRHWYESWYAPNNATLVVVGDVTADEVKTLAKRYFGEIPWRQLPPARK 224 Query: 133 PEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPP-VLAFALGTLGFLSPFDFKEHKKVF 191 P + + ++ TQ+P ++ F + +LG ++ Sbjct: 225 PLELAEPGE-------------RRLKLYVRTQLPNLIMGFNVPSLGSSENPREVNALRLI 271 Query: 192 QEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMN 226 ++ +RLE ++ + +S A N Sbjct: 272 GALLDGGYSARLASRLE-RGEELVAGASTYYDAFN 305 >2NVO-A nrPDB Length = 535 Score = 28.6 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 35/199 (17%), Positives = 63/199 (31%), Gaps = 52/199 (26%) Query: 172 ALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTR----LECHLKKKDSNS--------- 218 LG +G L+P D + V + + A R L+ L Sbjct: 280 NLGRVGVLTPNDSATVQAVIERLTDPAALKRGRIHPLDALKARLVYAQGQGVRGKGTWLP 339 Query: 219 -SIVTHAMNDIF------LHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGSTAYSL 271 V A+ + F + N+ HL LD+ +GS Sbjct: 340 VPRVVDALEEAFTLAFGNVQPANTRHLLALDV--------------------SGSMTCGD 379 Query: 272 SAGGSIVSPLVPAILMTPIC----PRSLS------FRPLILPHSSHIR--IKIGSKLNQK 319 AG ++P + A M+ I P +L+ FRPL + + ++ ++ Sbjct: 380 VAGVPGLTPNMAAAAMSLIALRTEPDALTMGFAEQFRPLGITPRDTLESAMQKAQSVSFG 439 Query: 320 PVNSVVKLSVDGIPQQDLD 338 + + + D+D Sbjct: 440 GTDCAQPILWAAQERLDVD 458 >3IU0-A nrPDB Length = 382 Score = 28.6 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 44/135 (32%), Gaps = 10/135 (7%) Query: 249 FLTRTTADGVALATPTGSTAYSLSAGGSIV-SPLVPAILMTPICPRSLSFRPLILPHSSH 307 R TAD VA +A + S+ G +P + P P P + Sbjct: 13 ETYRLTADDVANINALNESAPAASSAGPSFRAPDSDDRVTPPAEPLDRMPDPYRPSYGRA 72 Query: 308 IRIKIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRK--- 364 + + V S DG QQ + E VG +++ Q PT R Sbjct: 73 ETVVNNYIRKWQQVYSHR----DGRKQQMTEEQREWLSYGCVGVTWVNSGQYPTNRLAFA 128 Query: 365 --TENDFNNSKKPKR 377 E+ F N K R Sbjct: 129 SFDEDRFKNELKNGR 143 >5G04-F nrPDB Length = 824 Score = 28.2 bits (61), Expect = 7.0, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 45/134 (33%), Gaps = 10/134 (7%) Query: 222 THAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTG----------STAYSL 271 T +N + L NS + N D + + D V L T T T SL Sbjct: 209 TIELNRLNLESSNSKYSLNTDSSVSYIDSAVISPDTVPLGTGTSILSKQVQNKPKTGRSL 268 Query: 272 SAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVKLSVDG 331 G + +SPL P+ + P+ S + +++ + SV ++ G Sbjct: 269 LGGPAALSPLTPSFGILPLETPSPGDGSYLQNYTNTPPVIDVPSTGAPSKKSVARIGQTG 328 Query: 332 IPQQDLDVGDEIYV 345 G+ V Sbjct: 329 TKSVFSQSGNSREV 342 >2ZTN-A nrPDB Length = 478 Score = 28.2 bits (61), Expect = 7.5, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 39/111 (35%), Gaps = 9/111 (8%) Query: 98 EVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGV 157 +V ++VQP +A E+ + + + TG ++ +++ + G Sbjct: 103 DVRILVQPGIASELVIPSERLHYRNQGWRSVETTGVAEEEATSGLVMLCIHG-------- 154 Query: 158 SMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLE 208 S + P ALG L F +F+ SR R RL Sbjct: 155 SPVNSYTNTPYTG-ALGLLDFALELEFRNLTPGNTNTRVSRYTSTARHRLR 204 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.124 0.321 Lambda K H 0.267 0.0383 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,230,046 Number of Sequences: 36641 Number of extensions: 538551 Number of successful extensions: 1656 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 1586 Number of HSP's gapped (non-prelim): 58 length of query: 414 length of database: 10,336,785 effective HSP length: 100 effective length of query: 314 effective length of database: 6,672,685 effective search space: 2095223090 effective search space used: 2095223090 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 60 (27.8 bits)