BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q06520 (285 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1OV4-A nrPDB 583 e-167 1Q1Q-A nrPDB 295 2e-80 1Q22-A nrPDB 295 2e-80 2ZVQ-X nrPDB 211 4e-55 3BFX-A nrPDB 207 4e-54 1CJM-A nrPDB 205 2e-53 2REO-A nrPDB 203 7e-53 3U3O-A nrPDB 202 1e-52 2GWH-A nrPDB 201 2e-52 2Z5F-A nrPDB 198 2e-51 1AQU-A nrPDB 196 7e-51 4JVN-A nrPDB 188 2e-48 5X2B-D nrPDB 168 2e-42 1ZD1-A nrPDB 139 2e-33 1Q44-A nrPDB 100 7e-22 1X8L-A nrPDB 95 4e-20 5MEK-A nrPDB 95 4e-20 3NIB-A nrPDB 52 3e-07 3MGC-A nrPDB 50 1e-06 4EEC-A nrPDB 44 8e-05 5JH8-A nrPDB 32 0.29 3RNL-A nrPDB 32 0.43 1V5E-A nrPDB 30 1.4 4GBM-A nrPDB 28 3.4 1NST-A nrPDB 28 3.9 6NEQ-g nrPDB 28 5.1 3JD5-g nrPDB 28 5.2 6GAW-Ag nrPDB 28 6.6 4FNP-A nrPDB 27 8.3 6MVG-A nrPDB 27 8.6 >1OV4-A nrPDB Length = 293 Score = 583 bits (1503), Expect = e-167, Method: Compositional matrix adjust. Identities = 283/284 (99%), Positives = 283/284 (99%) Query: 2 SDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKG 61 SDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKG Sbjct: 10 SDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKG 69 Query: 62 DAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMR 121 DAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMR Sbjct: 70 DAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMR 129 Query: 122 NPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLL 181 NPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLL Sbjct: 130 NPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLL 189 Query: 182 LSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVD 241 LSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVD Sbjct: 190 LSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVD 249 Query: 242 KAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 285 K QLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE Sbjct: 250 KTQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 293 >1Q1Q-A nrPDB Length = 350 Score = 295 bits (754), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 137/286 (47%), Positives = 199/286 (69%), Gaps = 3/286 (1%) Query: 1 MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSK 60 + ++ ++G+ FP + E++ + +RD+D+ I+TYPKSGT W+ EI+CL+ + Sbjct: 12 LPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEIICLILKE 71 Query: 61 GDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLM 120 GD WI+SVPIWER+PW E+ +G +L + SPRL SSHLPIQ+F K+FFSSKAKVIY+ Sbjct: 72 GDPSWIRSVPIWERAPWCETIVGAFSLPDQYSPRLMSSHLPIQIFTKAFFSSKAKVIYMG 131 Query: 121 RNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFL 180 RNPRDV+VS Y + K +K P + +++ F +G V +GSWFDHI GW+ M+ + NFL Sbjct: 132 RNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRMKGKDNFL 191 Query: 181 LLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVV 240 ++YEEL+QD ++E+IC FLG+ L E L ++ +S+F +MK N MSNY+LL + Sbjct: 192 FITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTLLPPSLLD 251 Query: 241 D-KAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 285 + LRKGV GDWKNHFTVAQ+E FD+ ++++M +P FPW+ Sbjct: 252 HRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRGMP--TFPWD 295 >1Q22-A nrPDB Length = 299 Score = 295 bits (754), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 137/286 (47%), Positives = 199/286 (69%), Gaps = 3/286 (1%) Query: 1 MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSK 60 + ++ ++G+ FP + E++ + +RD+D+ I+TYPKSGT W+ EI+CL+ + Sbjct: 14 LPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEIICLILKE 73 Query: 61 GDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLM 120 GD WI+SVPIWER+PW E+ +G +L + SPRL SSHLPIQ+F K+FFSSKAKVIY+ Sbjct: 74 GDPSWIRSVPIWERAPWCETIVGAFSLPDQYSPRLMSSHLPIQIFTKAFFSSKAKVIYMG 133 Query: 121 RNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFL 180 RNPRDV+VS Y + K +K P + +++ F +G V +GSWFDHI GW+ M+ + NFL Sbjct: 134 RNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRMKGKDNFL 193 Query: 181 LLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVV 240 ++YEEL+QD ++E+IC FLG+ L E L ++ +S+F +MK N MSNY+LL + Sbjct: 194 FITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTLLPPSLLD 253 Query: 241 D-KAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 285 + LRKGV GDWKNHFTVAQ+E FD+ ++++M +P FPW+ Sbjct: 254 HRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRGMP--TFPWD 297 >2ZVQ-X nrPDB Length = 295 Score = 211 bits (536), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 110/257 (42%), Positives = 165/257 (64%), Gaps = 10/257 (3%) Query: 28 DEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEI----- 82 + F R +D++I TYPKSGT W++EIL L+++ GDA+ + I++R P++E I Sbjct: 32 ESFEARPDDILISTYPKSGTTWVSEILDLIYNNGDAEKCKRDAIYKRVPFMELIIPGITN 91 Query: 83 GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKK 142 G L+ SPR+ +HLP+QL P SF+ + K+IY+ RN +DV+VS Y+F++ K + Sbjct: 92 GVEMLNNMPSPRIVKTHLPVQLLPSSFWKNDCKIIYVARNAKDVVVSYYYFYQMAKIHPE 151 Query: 143 PKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFL 202 P +WEE+ E F G V +G W+DH+ W R+E L L YE++K++ I+KI +FL Sbjct: 152 PGTWEEFLEKFMAGQVSFGPWYDHVKSWWEKRKEYRILYLFYEDMKENPKCEIQKILKFL 211 Query: 203 GKTLEPEELNLILKNSSFQSMKENKMSNYSLL---SVDYVVDKAQLLRKGVSGDWKNHFT 259 K + E LN IL +SSF MKEN +NY+ + +D+ V + +RKG+SGDWKN FT Sbjct: 212 EKDIPEEILNKILYHSSFSVMKENPSANYTTMMKEEMDHSV--SPFMRKGISGDWKNQFT 269 Query: 260 VAQAEDFDKLFQEKMAD 276 VAQ E F++ + +KM D Sbjct: 270 VAQYEKFEEDYVKKMED 286 >3BFX-A nrPDB Length = 296 Score = 207 bits (527), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 102/252 (40%), Positives = 153/252 (60%), Gaps = 8/252 (3%) Query: 30 FVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVE-----SEIGY 84 F + +D++I TYPK+GT W+ EI+ ++ GD + Q I R P++E G Sbjct: 35 FEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQPSGV 94 Query: 85 TALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPK 144 SPR+ +HL QL P SF+ + K +Y+ RN +D +VS Y F + + P Sbjct: 95 EKAKAMPSPRILKTHLSTQLLPPSFWENNCKFLYVARNAKDCMVSYYHFQRMNHMLPDPG 154 Query: 145 SWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGK 204 +WEEYFE F G V++GSWFDH+ GW M++ L L YE++K+D I K+ QF+GK Sbjct: 155 TWEEYFETFINGKVVWGSWFDHVKGWWEMKDRHQILFLFYEDIKRDPKHEIRKVMQFMGK 214 Query: 205 TLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK--AQLLRKGVSGDWKNHFTVAQ 262 ++ L+ I++ +SF+ MKEN M+N S +S ++D+ + +RKG GDWKNHFTVAQ Sbjct: 215 KVDETVLDKIVQETSFEKMKENPMTNRSTVS-KSILDQSISSFMRKGTVGDWKNHFTVAQ 273 Query: 263 AEDFDKLFQEKM 274 E FD++++ KM Sbjct: 274 NERFDEIYRRKM 285 >1CJM-A nrPDB Length = 295 Score = 205 bits (521), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 103/272 (37%), Positives = 165/272 (60%), Gaps = 11/272 (4%) Query: 12 AFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPI 71 P + + +E L ++ F R +D++I TYPKSGT W+++IL +++ GD + PI Sbjct: 17 GVPLIKYFAEALGPLQS-FQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPI 75 Query: 72 WERSPWVE-----SEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDV 126 + R P++E G L +T PRL SHLP+ L P++ K KV+Y+ RNP+DV Sbjct: 76 YVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDV 135 Query: 127 LVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEE 186 VS Y F + K +P +W+ + E F G V YGSW+ H+ W + L L YE+ Sbjct: 136 AVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYED 195 Query: 187 LKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLS---VDYVVDKA 243 +K++ R I+KI +F+G++L E ++ +++++SF+ MK+N M+NY+ + +D+ + + Sbjct: 196 MKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSI--S 253 Query: 244 QLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMA 275 +RKG++GDWK FTVAQ E FD + EKMA Sbjct: 254 PFMRKGMAGDWKTTFTVAQNERFDADYAEKMA 285 >2REO-A nrPDB Length = 305 Score = 203 bits (516), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 109/272 (40%), Positives = 164/272 (60%), Gaps = 10/272 (3%) Query: 12 AFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPI 71 PT+ E KV + F + +D+I+ TYPKSGT W+ EIL ++ + GD + + Sbjct: 26 GVPTLILSKEWWEKVAN-FQAKPDDLILATYPKSGTTWMHEILDMILNDGDVEKCKRAQT 84 Query: 72 WERSPWVESEIGYTA------LSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRD 125 +R ++E + + + E SP+L +HLP L P S + K++Y+ RNP+D Sbjct: 85 LDRHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPSHLIPPSIWKENCKIVYVARNPKD 144 Query: 126 VLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYE 185 LVS Y F + F+ P++ EE++E F G V+ GSWFDH+ GW ++ L L YE Sbjct: 145 CLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGSWFDHVKGWWAAKDMHRILYLFYE 204 Query: 186 ELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK--A 243 ++K+D R IEKI +FL K + E LN I+ ++SF MK+N M+NY+ L ++D + Sbjct: 205 DIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDVMKQNPMTNYTTLPTS-IMDHSIS 263 Query: 244 QLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMA 275 +RKG+ GDWKN+FTVAQ E+FDK +Q+KMA Sbjct: 264 PFMRKGMPGDWKNYFTVAQNEEFDKDYQKKMA 295 >3U3O-A nrPDB Length = 315 Score = 202 bits (515), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 100/270 (37%), Positives = 164/270 (60%), Gaps = 7/270 (2%) Query: 12 AFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPI 71 P + + +E L ++ F R +D++I TYPKSGT W+++IL +++ GD + PI Sbjct: 37 GVPLIKYFAEALGPLQS-FQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPI 95 Query: 72 WERSPWVESEI-----GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDV 126 + R P++E + G L +T +PRL +HLP+ L P++ K KV+Y+ RN +DV Sbjct: 96 FMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDV 155 Query: 127 LVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEE 186 VS Y F+ K +P +W+ + E F G V YGSW+ H+ W + L L YE+ Sbjct: 156 AVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYED 215 Query: 187 LKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-AQL 245 +K++ R I+KI +F+G +L E ++ +++++SF+ MK+N M+NY+ + +++ + Sbjct: 216 MKENPKREIQKILEFVGHSLPEETVDFMVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPF 275 Query: 246 LRKGVSGDWKNHFTVAQAEDFDKLFQEKMA 275 +RKG++GDWK FTVAQ E FD + EKMA Sbjct: 276 MRKGMAGDWKTTFTVAQNERFDADYAEKMA 305 >2GWH-A nrPDB Length = 298 Score = 201 bits (512), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 100/254 (39%), Positives = 155/254 (61%), Gaps = 8/254 (3%) Query: 30 FVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEI-----GY 84 F + +D++I TYPK+GT W EI+ L+ ++GD + + P +R P++E +I G Sbjct: 37 FQAKPDDLLISTYPKAGTTWTQEIVELIQNEGDVEKSKRAPTHQRFPFLEMKIPSLGSGL 96 Query: 85 TALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPK 144 SPR+ +HLP L P S K+IY+ RNP+D +VS Y F + K + P Sbjct: 97 EQAHAMPSPRILKTHLPFHLLPPSLLEKNCKIIYVARNPKDNMVSYYHFQRMNKALPAPG 156 Query: 145 SWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGK 204 +WEEYFE F G V +GSW +H+ GW +++ L L YE++K++ I+K+ +F+GK Sbjct: 157 TWEEYFETFLAGKVCWGSWHEHVKGWWEAKDKHRILYLFYEDMKKNPKHEIQKLAEFIGK 216 Query: 205 TLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK--AQLLRKGVSGDWKNHFTVAQ 262 L+ + L+ I+ +SF MK+N M+NYS + + ++D + +RKG GDWK HFTVAQ Sbjct: 217 KLDDKVLDKIVHYTSFDVMKQNPMANYSSIPAE-IMDHSISPFMRKGAVGDWKKHFTVAQ 275 Query: 263 AEDFDKLFQEKMAD 276 E FD+ +++KM D Sbjct: 276 NERFDEDYKKKMTD 289 >2Z5F-A nrPDB Length = 298 Score = 198 bits (503), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 106/256 (41%), Positives = 156/256 (60%), Gaps = 9/256 (3%) Query: 28 DEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEI----- 82 ++F R +D++I TYPKSGT W++EI+ ++ + GD + + I E+ P +E + Sbjct: 34 EQFHSRPDDIVIATYPKSGTTWVSEIIDMILNDGDIEKCKRGFITEKVPMLEMTLPGLRT 93 Query: 83 -GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIK 141 G L + SPR+ +HLP L PKSF+ + K+IYL RN +DV VS Y F Sbjct: 94 SGIEQLEKNPSPRIVKTHLPTDLLPKSFWENNCKMIYLARNAKDVSVSYYHFDLMNNLQP 153 Query: 142 KPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQF 201 P +WEEY E F G V YGSWF H+ W +EE L L YE++K++ I+KI +F Sbjct: 154 FPGTWEEYLEKFLTGKVAYGSWFTHVKNWWKRKEEHPILFLYYEDMKENPKEEIKKIIRF 213 Query: 202 LGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVD--KAQLLRKGVSGDWKNHFT 259 L K L E L+ I+ ++SF+ MK+N + NY+ L V+D K+ +RKG +GDWKN+FT Sbjct: 214 LEKNLNDEILDRIIHHTSFEVMKDNPLVNYTHLPTT-VMDHSKSPFMRKGTAGDWKNYFT 272 Query: 260 VAQAEDFDKLFQEKMA 275 VAQ E FD +++ +M+ Sbjct: 273 VAQNEKFDAIYETEMS 288 >1AQU-A nrPDB Length = 297 Score = 196 bits (499), Expect = 7e-51, Method: Compositional matrix adjust. Identities = 97/253 (38%), Positives = 154/253 (60%), Gaps = 6/253 (2%) Query: 30 FVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEI-----GY 84 F+ R +D++I TYPKSGT W++E++ +++ +GD + + I+ R P++E G Sbjct: 36 FLARPDDLVIATYPKSGTTWISEVVYMIYKEGDVEKCKEDAIFNRIPYLECRNEDLINGI 95 Query: 85 TALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPK 144 L E ESPR+ +HLP +L P SF+ K+IYL RN +DV VS Y+F + PK Sbjct: 96 KQLKEKESPRIVKTHLPPKLLPASFWEKNCKMIYLCRNAKDVAVSYYYFLLMITSYPNPK 155 Query: 145 SWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGK 204 S+ E+ E F QG V YGSW+DH+ W + L + YE++K+D R + K+ +FL + Sbjct: 156 SFSEFVEKFMQGQVPYGSWYDHVKAWWEKSKNSRVLFMFYEDMKEDIRREVVKLIEFLER 215 Query: 205 TLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQ-LLRKGVSGDWKNHFTVAQA 263 E ++ I++++SFQ MK N +NY+++ + + K +RKG+ GDWKNHF A Sbjct: 216 KPSAELVDRIIQHTSFQEMKNNPSTNYTMMPEEMMNQKVSPFMRKGIIGDWKNHFPEALR 275 Query: 264 EDFDKLFQEKMAD 276 E FD+ ++++M D Sbjct: 276 ERFDEHYKQQMKD 288 >4JVN-A nrPDB Length = 294 Score = 188 bits (478), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 98/255 (38%), Positives = 152/255 (59%), Gaps = 6/255 (2%) Query: 28 DEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEI----- 82 + F R +D++I TYPKSGT W++EI+ +++ +GD + + I+ R P++E Sbjct: 31 EAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGDVEKCKEDVIFNRIPFLECRKENLMN 90 Query: 83 GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKK 142 G L E SPR+ +HLP +L P SF+ K+IYL RN +DV VS Y+F+ + Sbjct: 91 GVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRNAKDVAVSFYYFFLMVAGHPN 150 Query: 143 PKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFL 202 P S+ E+ E F QG V YGSW+ H+ W + L L YE+LK+D + + K+ FL Sbjct: 151 PGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFLFYEDLKEDIRKEVIKLIHFL 210 Query: 203 GKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-AQLLRKGVSGDWKNHFTVA 261 + E ++ I+ ++SFQ MK N +NY+ L + + K + +RKG++GDWKNHFT A Sbjct: 211 ERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQKLSPFMRKGITGDWKNHFTEA 270 Query: 262 QAEDFDKLFQEKMAD 276 E FDK ++++M + Sbjct: 271 LNEKFDKHYEQQMKE 285 >5X2B-D nrPDB Length = 281 Score = 168 bits (426), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 97/282 (34%), Positives = 155/282 (54%), Gaps = 21/282 (7%) Query: 8 FEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQ 67 + GI F TM SE L D F R++D+ +++YPKSGT+WLAE++ + I Sbjct: 6 YMGIFFSTMS--SEELLGSLDSFDAREDDIFLVSYPKSGTHWLAEVI---------ERIP 54 Query: 68 SVPIWERSPWVESEIG-YTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDV 126 I SP +I + L R +HL ++ P + + K+IY++RNP+D Sbjct: 55 DAGITLTSPIELGDISKFEELKRIPKRRAIPTHLNYEMLPVTVKQKQCKIIYIVRNPKDT 114 Query: 127 LVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEE 186 VS + ++++ + ++W + E F +G V+YGSWFDH+ W + +KN L + YEE Sbjct: 115 AVSMFHYYRDNPNLPSTETWAAFLELFLKGDVVYGSWFDHVLSWEEHKNDKNVLFIFYEE 174 Query: 187 LKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMS-----NYSLLSVDYVVD 241 +K+D ++++KI FLG + E+ I +++SF MK N N+ + ++ D Sbjct: 175 MKKDFVKSLKKITAFLGIDVNDSEMAKIARSTSFSEMKSNAAKENCDPNHVICAL--TSD 232 Query: 242 KAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKM--ADLPREL 281 + + RKGV GDW N+FT Q FD+LF EKM +D+ R L Sbjct: 233 RNLVFRKGVVGDWINYFTPKQNRGFDELFTEKMRNSDVGRCL 274 >1ZD1-A nrPDB Length = 284 Score = 139 bits (350), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 83/272 (30%), Positives = 143/272 (52%), Gaps = 17/272 (6%) Query: 5 FLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAK 64 + F G+ P F + ++ + F +R DV I+TYPKSGT+ L E++ L+ D Sbjct: 19 YFEFHGVRLPP--FCRGKMEEIAN-FPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPD 75 Query: 65 WIQSVPIWERSPWVE-SEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNP 123 I + I E+ P +E + G + E SPRL SHLP + P + +KVIY+ RNP Sbjct: 76 EIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNP 135 Query: 124 RDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLS 183 +D++VS Y F ++++ + +++E+ F + YGSWF+H+ + R + N L L Sbjct: 136 KDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLK 195 Query: 184 YEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKA 243 YE++ +D +E++ +FLG + + +L + ++ ++ N L V Sbjct: 196 YEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC---HQLVDQCCNAEALPVG------ 246 Query: 244 QLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMA 275 +G G WK+ FTV+ E FD ++++KM Sbjct: 247 ----RGRVGLWKDIFTVSMNEKFDLVYKQKMG 274 >1Q44-A nrPDB Length = 326 Score = 100 bits (249), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 85/275 (30%), Positives = 138/275 (50%), Gaps = 42/275 (15%) Query: 26 VRDEFVIRDEDVIILTYPKSGTNWL-AEILCLMH-------SKGDAKWIQS-----VPIW 72 + F +D D+I++T PKSGT WL A + L++ S G+ + + VP Sbjct: 57 CQKRFEAKDSDIILVTNPKSGTTWLKALVFALLNRHKFPVSSSGNHPLLVTNPHLLVPFL 116 Query: 73 ERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYF 132 E + + +++L SPRL ++H+ P+S SS K++Y RNP+D+ VS + Sbjct: 117 EGVYYESPDFDFSSLP---SPRLMNTHISHLSLPESVKSSSCKIVYCCRNPKDMFVSLWH 173 Query: 133 FWKNMKFIKKPKSWEEY-----FEWFCQGTVLYGSWFDHI-HGWMPMREEKN-FLLLSYE 185 F K + P+ +Y E FC+G + G ++DHI W RE N L ++YE Sbjct: 174 FGKKL----APEETADYPIEKAVEAFCEGKFIGGPFWDHILEYWYASRENPNKVLFVTYE 229 Query: 186 ELKQDTGRTIEKICQFLGKTL-EPEELNLILKNSSFQSM------KENKMSNYSLLSVDY 238 ELK+ T +++I +FL E EE+ I+K SF+S+ KE K+ N Sbjct: 230 ELKKQTEVEMKRIAEFLECGFIEEEEVREIVKLCSFESLSNLEVNKEGKLPNG------- 282 Query: 239 VVDKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEK 273 ++ RKG G W++ + + AE+ D+ +EK Sbjct: 283 -IETKTFFRKGEIGGWRDTLSESLAEEIDRTIEEK 316 >1X8L-A nrPDB Length = 351 Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 54/195 (27%), Positives = 102/195 (52%), Gaps = 7/195 (3%) Query: 85 TALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPK 144 A+ TE R +HLP+ L P + + K++YL R+PRDV VS + + + + K Sbjct: 151 AAVPPTEK-RFVKTHLPLSLMPPNMLDT-VKMVYLARDPRDVAVSSFHHARLLYLLNKQS 208 Query: 145 SWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGK 204 ++++++E F +G +F+H+ R + N L L YE+ +D +I +I FLGK Sbjct: 209 NFKDFWEMFHRGLYTLTPYFEHVKEAWAKRHDPNMLFLFYEDYLKDLPGSIARIADFLGK 268 Query: 205 TLEPEELNLILKNSSFQSMKEN---KMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHFTVA 261 L E++ + ++ +F+ K N M +Y + + + D +RKG +G W+++F Sbjct: 269 KLSEEQIQRLSEHLNFEKFKNNGAVNMEDYREIGI--LADGEHFIRKGKAGCWRDYFDEE 326 Query: 262 QAEDFDKLFQEKMAD 276 + +K ++ + D Sbjct: 327 MTKQAEKWIKDNLKD 341 >5MEK-A nrPDB Length = 322 Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 71/262 (27%), Positives = 121/262 (46%), Gaps = 19/262 (7%) Query: 30 FVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSP-----WVESEIGY 84 F R D ++ +YPK+GT WL + + ++ S P+ +R+P ++E + + Sbjct: 54 FQARPSDFLVCSYPKTGTTWLKALTFAIANRSRFD-DSSNPLLKRNPHEFVPYIEIDFPF 112 Query: 85 ---TALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIK 141 + + + LFS+H+P +L P S S K++Y+ R P+D +S + F + Sbjct: 113 FPEVDVLKDKGNTLFSTHIPYELLPDSVVKSGCKMVYIWREPKDTFISMWTFLHKERTEL 172 Query: 142 KPKS-WEEYFEWFCQGTVLYGSWFDHIHGWMPMREEK--NFLLLSYEELKQDTGRTIEKI 198 P S EE F+ FC+G YG + +HI + +E L L YE ++ D ++ + Sbjct: 173 GPVSNLEESFDMFCRGLSGYGPYLNHILAYWKAYQENPDRILFLKYETMRADPLPYVKSL 232 Query: 199 CQFLGKTLEPEELNLILKN-----SSFQSMKENKMSNYSLLSVDY--VVDKAQLLRKGVS 251 +F+G EE + SF+++K + + D V + RKG Sbjct: 233 AEFMGHGFTAEEEEKGVVEKVVNLCSFETLKNLEANKGEKDREDRPGVYANSAYFRKGKV 292 Query: 252 GDWKNHFTVAQAEDFDKLFQEK 273 GDW N+ T A D L +EK Sbjct: 293 GDWSNYLTPEMAARIDGLMEEK 314 >3NIB-A nrPDB Length = 309 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 52/208 (25%), Positives = 90/208 (43%), Gaps = 27/208 (12%) Query: 39 ILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEI------GYTALSETES 92 I +YPK+G WL C++ + K Q+ W+ V E+ G +E Sbjct: 41 IASYPKAGNTWLR---CMLAAYITGKAPQT---WKDMETVSLELEGMLHLGDMPPTEPTK 94 Query: 93 PRLFSSHLPIQLFPKSFFS-SKAKVIYLMRNPRDVLVSGYFFW--------KNMKFIKKP 143 P L +HL + +S + AKV+YL+RNPRD+L+S + F + Sbjct: 95 PVLVKTHLKADVPVLGLYSEATAKVLYLVRNPRDILLSAMRMTAISRDDMESSRTFARDF 154 Query: 144 KSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEK----NFLLLSYEELKQDTGRTIEKIC 199 + E G GSW +++ W ++ + L + YE+LK D +I Sbjct: 155 IANEGLRMRGRGGGAGLGSWPENVRIWTESSRDRFPNADVLTMRYEDLKGDPVARFSEIV 214 Query: 200 QF--LGKTLEPEELNLILKNSSFQSMKE 225 +F LG ++ E++ + + + M+E Sbjct: 215 EFLDLGDPVDIEDIRRAVAACTLERMRE 242 >3MGC-A nrPDB Length = 319 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 55/211 (26%), Positives = 95/211 (45%), Gaps = 31/211 (14%) Query: 39 ILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWE----RSPWVESEIGYTALSETE--S 92 I +YPK+G W + C++ + K Q +W S +E+ + + L E Sbjct: 41 IASYPKAGNTW---VRCMLAAYITGKAPQ---VWNDIDAESLTLEAMLRFGDLPPAEPME 94 Query: 93 PRLFSSHLPIQLFPKSFFS-SKAKVIYLMRNPRDVLVSGYFFW--------KNMKFIKKP 143 P L +HL + + + AKV+YL+RNPRD+L+S K+ F +K Sbjct: 95 PVLVKTHLKADVPVLGLYGEATAKVLYLVRNPRDMLLSSMRMASISRDDVEKSRDFARKF 154 Query: 144 KSWEEYFEW---FCQGTVLYGSWFDHIHGWMPMREEK----NFLLLSYEELKQDTGRTIE 196 + E W G V GSW +++ W ++ + L + YE+LK D Sbjct: 155 IA-NEGLGWNALGAGGGVGLGSWPENVRSWTESSSDRFPNADVLTMRYEDLKGDPVARFS 213 Query: 197 KICQF--LGKTLEPEELNLILKNSSFQSMKE 225 +I +F LG ++ E++ + S+ + M+E Sbjct: 214 EIVEFLDLGGPVDIEDIRRAVAASTLERMRE 244 >4EEC-A nrPDB Length = 286 Score = 43.9 bits (102), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 53/211 (25%), Positives = 92/211 (43%), Gaps = 38/211 (18%) Query: 39 ILTYPKSGTNWLAEILCLMHSKGDAKWIQSVP-IWERSPWVESEI--GYTALSETESPRL 95 I +YPK+G +WL C++ S + +++ P I P +E + G ++ + L Sbjct: 23 IASYPKAGGHWLR---CMLTSYVTGEPVETWPGIQAGVPHLEGLLRDGEAPSADPDEQVL 79 Query: 96 FSSHL----PIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFI-----KKPKSW 146 ++H P+ F + S AKV+ L+RNPRD ++S MK I + + Sbjct: 80 LATHFTADRPVLRF---YRESTAKVVCLIRNPRDAMLS----LMRMKGIPPEDVEACRKI 132 Query: 147 EEYF---EWFCQGTVLYG---------SWFDHIHGWMPMREEKNFLLLSYEELKQDTGRT 194 E F E F + G SW D +H P L + YE+L++D Sbjct: 133 AETFIADEGFSSVRIWAGEGSWPENIRSWTDSVHESFP---NAAVLAVRYEDLRKDPEGE 189 Query: 195 IEKICQFLGKTLEPEELNLILKNSSFQSMKE 225 + K+ FL + + + + N + + M+E Sbjct: 190 LWKVVDFL-ELGGRDGVADAVANCTLERMRE 219 >5JH8-A nrPDB Length = 317 Score = 32.0 bits (71), Expect = 0.29, Method: Compositional matrix adjust. Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Query: 175 EEKNF--LLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYS 232 ++K F + + +E + Q Q LG+ L + L LI+ +F + EN +NY Sbjct: 101 QDKRFSGINVDFEAVAQGDRNNFSHFIQVLGRALHAKGLKLIVSVPAFSAKDENHPANYG 160 Query: 233 --LLSVDYVVDKAQLL 246 L ++ D Q++ Sbjct: 161 YDLRALGAAADYLQIM 176 >3RNL-A nrPDB Length = 311 Score = 31.6 bits (70), Expect = 0.43, Method: Compositional matrix adjust. Identities = 21/101 (20%), Positives = 46/101 (45%), Gaps = 14/101 (13%) Query: 114 AKVIYLMRNPRDVLVSGYFFW-----KNMKF----IKKPKSWEEYFE--WFCQGTVLYGS 162 AK++ ++RNP D S Y + + F K+ + +++E W+ + LY + Sbjct: 110 AKILIMLRNPVDRAFSAYMHLVRDERETLSFRESLAKEEERIRQHYEPLWYYRAVGLYAA 169 Query: 163 WFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLG 203 + ++ + + ++ +EE +D + + C FLG Sbjct: 170 ---QVKRYLDVFGREQVKVILFEEFARDPVQVVRDCCAFLG 207 >1V5E-A nrPDB Length = 590 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 38/68 (55%), Gaps = 8/68 (11%) Query: 211 LNLILKNSSFQSMKEN-KMSNYSLLSVDYV-VDKAQLLR-KGVSGDWKNHFTVAQAEDFD 267 +N++ N+ + +K + +N +L VD+ VD A++ +G G FTV++ ED D Sbjct: 461 INVVFSNTEYAFIKNKYEDTNKNLFGVDFTDVDYAKIAEAQGAKG-----FTVSRIEDMD 515 Query: 268 KLFQEKMA 275 ++ E +A Sbjct: 516 RVMAEAVA 523 >4GBM-A nrPDB Length = 323 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 31/134 (23%), Positives = 54/134 (40%), Gaps = 12/134 (8%) Query: 84 YTALSETESPRLFSSHLPIQLFPKSFFS------SKAKVIYLMRNPRDVLVSGYFFWKNM 137 Y L E +PRL P + + +K IYL+R+P V+ S + M Sbjct: 121 YGMLQENIAPRLLVDKSPTYAMEPTILERGEALFANSKYIYLVRHPYSVIES----FVRM 176 Query: 138 KFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEK 197 + K EE + ++ +I ++ E + + YE+L + + + + Sbjct: 177 RMQKLVGLGEE--NPYRVAEQVWAKSNQNILNFLSQLEPERQHQIRYEDLVKKPQQVLSQ 234 Query: 198 ICQFLGKTLEPEEL 211 +C FL EPE L Sbjct: 235 LCDFLNVPFEPELL 248 >1NST-A nrPDB Length = 325 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 23/107 (21%), Positives = 44/107 (41%), Gaps = 17/107 (15%) Query: 113 KAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFC-------------QGTVL 159 KAKV+ ++ NP D Y ++++ + P + + F Q L Sbjct: 139 KAKVLTILINPAD---RAYSWYQHQRAHDDPVALKYTFHEVITAGSDASSKLRALQNRCL 195 Query: 160 YGSWF-DHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKT 205 W+ HI W+ L+L + L+ + + ++ + +FLG T Sbjct: 196 VPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLGVT 242 >6NEQ-g nrPDB Length = 351 Score = 28.1 bits (61), Expect = 5.1, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 19/40 (47%) Query: 246 LRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 285 LRK V DW+ V LF+ + A LP+EL E Sbjct: 246 LRKMVKNDWQGGAIVLTVSQTGSLFKPRKAYLPQELLGKE 285 >3JD5-g nrPDB Length = 397 Score = 27.7 bits (60), Expect = 5.2, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 19/40 (47%) Query: 246 LRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 285 LRK V DW+ V LF+ + A LP+EL E Sbjct: 292 LRKMVKNDWQGGAIVLTVSQTGSLFKPRKAYLPQELLGKE 331 >6GAW-Ag nrPDB Length = 397 Score = 27.7 bits (60), Expect = 6.6, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 19/40 (47%) Query: 246 LRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 285 LRK V DW+ V LF+ + A LP+EL E Sbjct: 292 LRKMVKNDWQGGAIVLTVSQTGSLFKPRNAYLPQELLGKE 331 >4FNP-A nrPDB Length = 729 Score = 27.3 bits (59), Expect = 8.3, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 16/39 (41%) Query: 61 GDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSH 99 D WI W R W+E T + ES R SSH Sbjct: 188 ADYDWIHLPGAWGRERWIERRPLVTGVQAAESRRGASSH 226 >6MVG-A nrPDB Length = 777 Score = 27.3 bits (59), Expect = 8.6, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 17/36 (47%), Gaps = 2/36 (5%) Query: 139 FIKKPK--SWEEYFEWFCQGTVLYGSWFDHIHGWMP 172 +I+ P S+ YF W+ T + G W D H P Sbjct: 447 YIQIPDVVSYNHYFGWYGGDTSMNGPWMDEFHKEFP 482 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1OV4-A nrPDB 414 e-116 1Q22-A nrPDB 387 e-108 3U3O-A nrPDB 384 e-107 1CJM-A nrPDB 383 e-107 1Q1Q-A nrPDB 382 e-107 2REO-A nrPDB 375 e-104 3BFX-A nrPDB 369 e-103 2Z5F-A nrPDB 368 e-102 2GWH-A nrPDB 367 e-102 2ZVQ-X nrPDB 363 e-101 4JVN-A nrPDB 360 e-100 1AQU-A nrPDB 357 4e-99 1ZD1-A nrPDB 313 4e-86 5X2B-D nrPDB 311 2e-85 5MEK-A nrPDB 249 8e-67 1Q44-A nrPDB 232 1e-61 1X8L-A nrPDB 229 1e-60 3MGC-A nrPDB 180 8e-46 4EEC-A nrPDB 172 2e-43 3NIB-A nrPDB 172 2e-43 Sequences not found previously or not previously below threshold: 4GBM-A nrPDB 51 6e-07 1T8T-A nrPDB 47 1e-05 4GOX-A nrPDB 42 3e-04 3RNL-A nrPDB 39 0.002 1NST-A nrPDB 37 0.010 3WO8-A nrPDB 34 0.060 3F5F-A nrPDB 34 0.090 1ZRH-A nrPDB 34 0.090 6DXU-D nrPDB 31 0.55 4WHN-A nrPDB 30 0.90 2EMT-A nrPDB 30 0.90 1X3Z-A nrPDB 30 1.2 1WZ2-A nrPDB 29 2.2 3K8L-A nrPDB 29 2.5 1E5W-A nrPDB 29 2.7 4YL8-A nrPDB 29 2.8 6AGH-A nrPDB 29 3.0 4RM9-A nrPDB 28 3.5 4RMA-A nrPDB 28 3.9 3AP1-A nrPDB 28 4.1 1PQU-A nrPDB 28 4.6 2GLJ-A nrPDB 28 4.7 5Y81-H nrPDB 28 5.8 6EAZ-A nrPDB 28 6.4 5HFU-A nrPDB 27 8.1 >1OV4-A nrPDB Length = 293 Score = 414 bits (1065), Expect = e-116, Method: Composition-based stats. Identities = 283/284 (99%), Positives = 283/284 (99%) Query: 2 SDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKG 61 SDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKG Sbjct: 10 SDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKG 69 Query: 62 DAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMR 121 DAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMR Sbjct: 70 DAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMR 129 Query: 122 NPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLL 181 NPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLL Sbjct: 130 NPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLL 189 Query: 182 LSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVD 241 LSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVD Sbjct: 190 LSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVD 249 Query: 242 KAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 285 K QLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE Sbjct: 250 KTQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 293 >1Q22-A nrPDB Length = 299 Score = 387 bits (993), Expect = e-108, Method: Composition-based stats. Identities = 137/286 (47%), Positives = 199/286 (69%), Gaps = 3/286 (1%) Query: 1 MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSK 60 + ++ ++G+ FP + E++ + +RD+D+ I+TYPKSGT W+ EI+CL+ + Sbjct: 14 LPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEIICLILKE 73 Query: 61 GDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLM 120 GD WI+SVPIWER+PW E+ +G +L + SPRL SSHLPIQ+F K+FFSSKAKVIY+ Sbjct: 74 GDPSWIRSVPIWERAPWCETIVGAFSLPDQYSPRLMSSHLPIQIFTKAFFSSKAKVIYMG 133 Query: 121 RNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFL 180 RNPRDV+VS Y + K +K P + +++ F +G V +GSWFDHI GW+ M+ + NFL Sbjct: 134 RNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRMKGKDNFL 193 Query: 181 LLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVV 240 ++YEEL+QD ++E+IC FLG+ L E L ++ +S+F +MK N MSNY+LL + Sbjct: 194 FITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTLLPPSLLD 253 Query: 241 D-KAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 285 + LRKGV GDWKNHFTVAQ+E FD+ ++++M +P FPW+ Sbjct: 254 HRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRGMP--TFPWD 297 >3U3O-A nrPDB Length = 315 Score = 384 bits (987), Expect = e-107, Method: Composition-based stats. Identities = 100/271 (36%), Positives = 163/271 (60%), Gaps = 7/271 (2%) Query: 12 AFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPI 71 P + + +E L ++ F R +D++I TYPKSGT W+++IL +++ GD + PI Sbjct: 37 GVPLIKYFAEALGPLQ-SFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPI 95 Query: 72 WERSPWVE-----SEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDV 126 + R P++E G L +T +PRL +HLP+ L P++ K KV+Y+ RN +DV Sbjct: 96 FMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDV 155 Query: 127 LVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEE 186 VS Y F+ K +P +W+ + E F G V YGSW+ H+ W + L L YE+ Sbjct: 156 AVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYED 215 Query: 187 LKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-AQL 245 +K++ R I+KI +F+G +L E ++ +++++SF+ MK+N M+NY+ + +++ + Sbjct: 216 MKENPKREIQKILEFVGHSLPEETVDFMVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPF 275 Query: 246 LRKGVSGDWKNHFTVAQAEDFDKLFQEKMAD 276 +RKG++GDWK FTVAQ E FD + EKMA Sbjct: 276 MRKGMAGDWKTTFTVAQNERFDADYAEKMAG 306 >1CJM-A nrPDB Length = 295 Score = 383 bits (983), Expect = e-107, Method: Composition-based stats. Identities = 102/271 (37%), Positives = 163/271 (60%), Gaps = 7/271 (2%) Query: 12 AFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPI 71 P + + +E L ++ F R +D++I TYPKSGT W+++IL +++ GD + PI Sbjct: 17 GVPLIKYFAEALGPLQ-SFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPI 75 Query: 72 WERSPWVES-----EIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDV 126 + R P++E G L +T PRL SHLP+ L P++ K KV+Y+ RNP+DV Sbjct: 76 YVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDV 135 Query: 127 LVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEE 186 VS Y F + K +P +W+ + E F G V YGSW+ H+ W + L L YE+ Sbjct: 136 AVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYED 195 Query: 187 LKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-AQL 245 +K++ R I+KI +F+G++L E ++ +++++SF+ MK+N M+NY+ + + + + Sbjct: 196 MKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPF 255 Query: 246 LRKGVSGDWKNHFTVAQAEDFDKLFQEKMAD 276 +RKG++GDWK FTVAQ E FD + EKMA Sbjct: 256 MRKGMAGDWKTTFTVAQNERFDADYAEKMAG 286 >1Q1Q-A nrPDB Length = 350 Score = 382 bits (982), Expect = e-107, Method: Composition-based stats. Identities = 137/286 (47%), Positives = 199/286 (69%), Gaps = 3/286 (1%) Query: 1 MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSK 60 + ++ ++G+ FP + E++ + +RD+D+ I+TYPKSGT W+ EI+CL+ + Sbjct: 12 LPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEIICLILKE 71 Query: 61 GDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLM 120 GD WI+SVPIWER+PW E+ +G +L + SPRL SSHLPIQ+F K+FFSSKAKVIY+ Sbjct: 72 GDPSWIRSVPIWERAPWCETIVGAFSLPDQYSPRLMSSHLPIQIFTKAFFSSKAKVIYMG 131 Query: 121 RNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFL 180 RNPRDV+VS Y + K +K P + +++ F +G V +GSWFDHI GW+ M+ + NFL Sbjct: 132 RNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRMKGKDNFL 191 Query: 181 LLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVV 240 ++YEEL+QD ++E+IC FLG+ L E L ++ +S+F +MK N MSNY+LL + Sbjct: 192 FITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTLLPPSLLD 251 Query: 241 D-KAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE 285 + LRKGV GDWKNHFTVAQ+E FD+ ++++M +P FPW+ Sbjct: 252 HRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRGMP--TFPWD 295 >2REO-A nrPDB Length = 305 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 108/272 (39%), Positives = 161/272 (59%), Gaps = 8/272 (2%) Query: 12 AFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPI 71 PT+ E KV + F + +D+I+ TYPKSGT W+ EIL ++ + GD + + Sbjct: 26 GVPTLILSKEWWEKVAN-FQAKPDDLILATYPKSGTTWMHEILDMILNDGDVEKCKRAQT 84 Query: 72 WERSPWVESEIGYTALS------ETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRD 125 +R ++E + + E SP+L +HLP L P S + K++Y+ RNP+D Sbjct: 85 LDRHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPSHLIPPSIWKENCKIVYVARNPKD 144 Query: 126 VLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYE 185 LVS Y F + F+ P++ EE++E F G V+ GSWFDH+ GW ++ L L YE Sbjct: 145 CLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGSWFDHVKGWWAAKDMHRILYLFYE 204 Query: 186 ELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-AQ 244 ++K+D R IEKI +FL K + E LN I+ ++SF MK+N M+NY+ L + + Sbjct: 205 DIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDVMKQNPMTNYTTLPTSIMDHSISP 264 Query: 245 LLRKGVSGDWKNHFTVAQAEDFDKLFQEKMAD 276 +RKG+ GDWKN+FTVAQ E+FDK +Q+KMA Sbjct: 265 FMRKGMPGDWKNYFTVAQNEEFDKDYQKKMAG 296 >3BFX-A nrPDB Length = 296 Score = 369 bits (948), Expect = e-103, Method: Composition-based stats. Identities = 101/255 (39%), Positives = 150/255 (58%), Gaps = 6/255 (2%) Query: 28 DEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVE-----SEI 82 F + +D++I TYPK+GT W+ EI+ ++ GD + Q I R P++E Sbjct: 33 QSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQPS 92 Query: 83 GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKK 142 G SPR+ +HL QL P SF+ + K +Y+ RN +D +VS Y F + + Sbjct: 93 GVEKAKAMPSPRILKTHLSTQLLPPSFWENNCKFLYVARNAKDCMVSYYHFQRMNHMLPD 152 Query: 143 PKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFL 202 P +WEEYFE F G V++GSWFDH+ GW M++ L L YE++K+D I K+ QF+ Sbjct: 153 PGTWEEYFETFINGKVVWGSWFDHVKGWWEMKDRHQILFLFYEDIKRDPKHEIRKVMQFM 212 Query: 203 GKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-AQLLRKGVSGDWKNHFTVA 261 GK ++ L+ I++ +SF+ MKEN M+N S +S + + +RKG GDWKNHFTVA Sbjct: 213 GKKVDETVLDKIVQETSFEKMKENPMTNRSTVSKSILDQSISSFMRKGTVGDWKNHFTVA 272 Query: 262 QAEDFDKLFQEKMAD 276 Q E FD++++ KM Sbjct: 273 QNERFDEIYRRKMEG 287 >2Z5F-A nrPDB Length = 298 Score = 368 bits (944), Expect = e-102, Method: Composition-based stats. Identities = 106/271 (39%), Positives = 159/271 (58%), Gaps = 8/271 (2%) Query: 12 AFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPI 71 +P + K+ ++F R +D++I TYPKSGT W++EI+ ++ + GD + + I Sbjct: 19 GYPMTCAFASNWEKI-EQFHSRPDDIVIATYPKSGTTWVSEIIDMILNDGDIEKCKRGFI 77 Query: 72 WERSPWVESEI------GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRD 125 E+ P +E + G L + SPR+ +HLP L PKSF+ + K+IYL RN +D Sbjct: 78 TEKVPMLEMTLPGLRTSGIEQLEKNPSPRIVKTHLPTDLLPKSFWENNCKMIYLARNAKD 137 Query: 126 VLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYE 185 V VS Y F P +WEEY E F G V YGSWF H+ W +EE L L YE Sbjct: 138 VSVSYYHFDLMNNLQPFPGTWEEYLEKFLTGKVAYGSWFTHVKNWWKRKEEHPILFLYYE 197 Query: 186 ELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVD-KAQ 244 ++K++ I+KI +FL K L E L+ I+ ++SF+ MK+N + NY+ L + K+ Sbjct: 198 DMKENPKEEIKKIIRFLEKNLNDEILDRIIHHTSFEVMKDNPLVNYTHLPTTVMDHSKSP 257 Query: 245 LLRKGVSGDWKNHFTVAQAEDFDKLFQEKMA 275 +RKG +GDWKN+FTVAQ E FD +++ +M+ Sbjct: 258 FMRKGTAGDWKNYFTVAQNEKFDAIYETEMS 288 >2GWH-A nrPDB Length = 298 Score = 367 bits (943), Expect = e-102, Method: Composition-based stats. Identities = 99/253 (39%), Positives = 153/253 (60%), Gaps = 6/253 (2%) Query: 30 FVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEI-----GY 84 F + +D++I TYPK+GT W EI+ L+ ++GD + + P +R P++E +I G Sbjct: 37 FQAKPDDLLISTYPKAGTTWTQEIVELIQNEGDVEKSKRAPTHQRFPFLEMKIPSLGSGL 96 Query: 85 TALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPK 144 SPR+ +HLP L P S K+IY+ RNP+D +VS Y F + K + P Sbjct: 97 EQAHAMPSPRILKTHLPFHLLPPSLLEKNCKIIYVARNPKDNMVSYYHFQRMNKALPAPG 156 Query: 145 SWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGK 204 +WEEYFE F G V +GSW +H+ GW +++ L L YE++K++ I+K+ +F+GK Sbjct: 157 TWEEYFETFLAGKVCWGSWHEHVKGWWEAKDKHRILYLFYEDMKKNPKHEIQKLAEFIGK 216 Query: 205 TLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-AQLLRKGVSGDWKNHFTVAQA 263 L+ + L+ I+ +SF MK+N M+NYS + + + + +RKG GDWK HFTVAQ Sbjct: 217 KLDDKVLDKIVHYTSFDVMKQNPMANYSSIPAEIMDHSISPFMRKGAVGDWKKHFTVAQN 276 Query: 264 EDFDKLFQEKMAD 276 E FD+ +++KM D Sbjct: 277 ERFDEDYKKKMTD 289 >2ZVQ-X nrPDB Length = 295 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 111/271 (40%), Positives = 168/271 (61%), Gaps = 7/271 (2%) Query: 12 AFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPI 71 P +E +V + F R +D++I TYPKSGT W++EIL L+++ GDA+ + I Sbjct: 17 GIPLFWSIAEHWSQV-ESFEARPDDILISTYPKSGTTWVSEILDLIYNNGDAEKCKRDAI 75 Query: 72 WERSPWVESEI-----GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDV 126 ++R P++E I G L+ SPR+ +HLP+QL P SF+ + K+IY+ RN +DV Sbjct: 76 YKRVPFMELIIPGITNGVEMLNNMPSPRIVKTHLPVQLLPSSFWKNDCKIIYVARNAKDV 135 Query: 127 LVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEE 186 +VS Y+F++ K +P +WEE+ E F G V +G W+DH+ W R+E L L YE+ Sbjct: 136 VVSYYYFYQMAKIHPEPGTWEEFLEKFMAGQVSFGPWYDHVKSWWEKRKEYRILYLFYED 195 Query: 187 LKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-AQL 245 +K++ I+KI +FL K + E LN IL +SSF MKEN +NY+ + + + + Sbjct: 196 MKENPKCEIQKILKFLEKDIPEEILNKILYHSSFSVMKENPSANYTTMMKEEMDHSVSPF 255 Query: 246 LRKGVSGDWKNHFTVAQAEDFDKLFQEKMAD 276 +RKG+SGDWKN FTVAQ E F++ + +KM D Sbjct: 256 MRKGISGDWKNQFTVAQYEKFEEDYVKKMED 286 >4JVN-A nrPDB Length = 294 Score = 360 bits (923), Expect = e-100, Method: Composition-based stats. Identities = 98/255 (38%), Positives = 152/255 (59%), Gaps = 6/255 (2%) Query: 28 DEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESE-----I 82 + F R +D++I TYPKSGT W++EI+ +++ +GD + + I+ R P++E Sbjct: 31 EAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGDVEKCKEDVIFNRIPFLECRKENLMN 90 Query: 83 GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKK 142 G L E SPR+ +HLP +L P SF+ K+IYL RN +DV VS Y+F+ + Sbjct: 91 GVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRNAKDVAVSFYYFFLMVAGHPN 150 Query: 143 PKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFL 202 P S+ E+ E F QG V YGSW+ H+ W + L L YE+LK+D + + K+ FL Sbjct: 151 PGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFLFYEDLKEDIRKEVIKLIHFL 210 Query: 203 GKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-AQLLRKGVSGDWKNHFTVA 261 + E ++ I+ ++SFQ MK N +NY+ L + + K + +RKG++GDWKNHFT A Sbjct: 211 ERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQKLSPFMRKGITGDWKNHFTEA 270 Query: 262 QAEDFDKLFQEKMAD 276 E FDK ++++M + Sbjct: 271 LNEKFDKHYEQQMKE 285 >1AQU-A nrPDB Length = 297 Score = 357 bits (916), Expect = 4e-99, Method: Composition-based stats. Identities = 102/278 (36%), Positives = 163/278 (58%), Gaps = 9/278 (3%) Query: 5 FLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAK 64 F F G+ M R + + F+ R +D++I TYPKSGT W++E++ +++ +GD + Sbjct: 14 FGEFRGV---LMDKRFTKYWEDVEMFLARPDDLVIATYPKSGTTWISEVVYMIYKEGDVE 70 Query: 65 WIQSVPIWERSPWVESEI-----GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYL 119 + I+ R P++E G L E ESPR+ +HLP +L P SF+ K+IYL Sbjct: 71 KCKEDAIFNRIPYLECRNEDLINGIKQLKEKESPRIVKTHLPPKLLPASFWEKNCKMIYL 130 Query: 120 MRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNF 179 RN +DV VS Y+F + PKS+ E+ E F QG V YGSW+DH+ W + Sbjct: 131 CRNAKDVAVSYYYFLLMITSYPNPKSFSEFVEKFMQGQVPYGSWYDHVKAWWEKSKNSRV 190 Query: 180 LLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYV 239 L + YE++K+D R + K+ +FL + E ++ I++++SFQ MK N +NY+++ + + Sbjct: 191 LFMFYEDMKEDIRREVVKLIEFLERKPSAELVDRIIQHTSFQEMKNNPSTNYTMMPEEMM 250 Query: 240 VDK-AQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMAD 276 K + +RKG+ GDWKNHF A E FD+ ++++M D Sbjct: 251 NQKVSPFMRKGIIGDWKNHFPEALRERFDEHYKQQMKD 288 >1ZD1-A nrPDB Length = 284 Score = 313 bits (803), Expect = 4e-86, Method: Composition-based stats. Identities = 83/272 (30%), Positives = 143/272 (52%), Gaps = 17/272 (6%) Query: 5 FLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAK 64 + F G+ P F + ++ + F +R DV I+TYPKSGT+ L E++ L+ D Sbjct: 19 YFEFHGVRLPP--FCRGKMEEIAN-FPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPD 75 Query: 65 WIQSVPIWERSPWVE-SEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNP 123 I + I E+ P +E + G + E SPRL SHLP + P + +KVIY+ RNP Sbjct: 76 EIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNP 135 Query: 124 RDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLS 183 +D++VS Y F ++++ + +++E+ F + YGSWF+H+ + R + N L L Sbjct: 136 KDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLK 195 Query: 184 YEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKA 243 YE++ +D +E++ +FLG + + +L + ++ ++ N L V Sbjct: 196 YEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC---HQLVDQCCNAEALPVG------ 246 Query: 244 QLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMA 275 +G G WK+ FTV+ E FD ++++KM Sbjct: 247 ----RGRVGLWKDIFTVSMNEKFDLVYKQKMG 274 >5X2B-D nrPDB Length = 281 Score = 311 bits (798), Expect = 2e-85, Method: Composition-based stats. Identities = 97/283 (34%), Positives = 155/283 (54%), Gaps = 21/283 (7%) Query: 7 WFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWI 66 + GI F TM SE L D F R++D+ +++YPKSGT+WLAE++ + I Sbjct: 5 KYMGIFFSTM--SSEELLGSLDSFDAREDDIFLVSYPKSGTHWLAEVI---------ERI 53 Query: 67 QSVPIWERSPWVESEIG-YTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRD 125 I SP +I + L R +HL ++ P + + K+IY++RNP+D Sbjct: 54 PDAGITLTSPIELGDISKFEELKRIPKRRAIPTHLNYEMLPVTVKQKQCKIIYIVRNPKD 113 Query: 126 VLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYE 185 VS + ++++ + ++W + E F +G V+YGSWFDH+ W + +KN L + YE Sbjct: 114 TAVSMFHYYRDNPNLPSTETWAAFLELFLKGDVVYGSWFDHVLSWEEHKNDKNVLFIFYE 173 Query: 186 ELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKM-----SNYSLLSVDYVV 240 E+K+D ++++KI FLG + E+ I +++SF MK N N+ + ++ Sbjct: 174 EMKKDFVKSLKKITAFLGIDVNDSEMAKIARSTSFSEMKSNAAKENCDPNHVICAL--TS 231 Query: 241 DKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKM--ADLPREL 281 D+ + RKGV GDW N+FT Q FD+LF EKM +D+ R L Sbjct: 232 DRNLVFRKGVVGDWINYFTPKQNRGFDELFTEKMRNSDVGRCL 274 >5MEK-A nrPDB Length = 322 Score = 249 bits (637), Expect = 8e-67, Method: Composition-based stats. Identities = 72/291 (24%), Positives = 125/291 (42%), Gaps = 27/291 (9%) Query: 14 PTMGFRSETLRK--------VRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKW 65 P + + ++ F R D ++ +YPK+GT WL + + ++ Sbjct: 30 PLIEYGGYWWLPSLLEGCIHAQEFFQARPSDFLVCSYPKTGTTWLKALTFAIANRSRFD- 88 Query: 66 IQSVPIWER-----SPWVESEIGYTA---LSETESPRLFSSHLPIQLFPKSFFSSKAKVI 117 S P+ +R P++E + + + + + LFS+H+P +L P S S K++ Sbjct: 89 DSSNPLLKRNPHEFVPYIEIDFPFFPEVDVLKDKGNTLFSTHIPYELLPDSVVKSGCKMV 148 Query: 118 YLMRNPRDVLVSGYFFWKNMKFIKKPKS-WEEYFEWFCQGTVLYGSWFDHIHGWMPMREE 176 Y+ R P+D +S + F + P S EE F+ FC+G YG + +HI + +E Sbjct: 149 YIWREPKDTFISMWTFLHKERTELGPVSNLEESFDMFCRGLSGYGPYLNHILAYWKAYQE 208 Query: 177 K--NFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKN-----SSFQSMKENKMS 229 L L YE ++ D ++ + +F+G EE + SF+++K + + Sbjct: 209 NPDRILFLKYETMRADPLPYVKSLAEFMGHGFTAEEEEKGVVEKVVNLCSFETLKNLEAN 268 Query: 230 NYSLLSVDY--VVDKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLP 278 D V + RKG GDW N+ T A D L +EK Sbjct: 269 KGEKDREDRPGVYANSAYFRKGKVGDWSNYLTPEMAARIDGLMEEKFKGTG 319 >1Q44-A nrPDB Length = 326 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 81/299 (27%), Positives = 144/299 (48%), Gaps = 32/299 (10%) Query: 1 MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSK 60 + + F+G+ + + + F +D D+I++T PKSGT WL ++ + ++ Sbjct: 34 LVSEIYEFQGLWHTQAIL--QGILICQKRFEAKDSDIILVTNPKSGTTWLKALVFALLNR 91 Query: 61 --------GDAKWIQS-----VPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPK 107 G+ + + VP E + + +++L SPRL ++H+ P+ Sbjct: 92 HKFPVSSSGNHPLLVTNPHLLVPFLEGVYYESPDFDFSSL---PSPRLMNTHISHLSLPE 148 Query: 108 SFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEY-----FEWFCQGTVLYGS 162 S SS K++Y RNP+D+ VS + F K + P+ +Y E FC+G + G Sbjct: 149 SVKSSSCKIVYCCRNPKDMFVSLWHFGKKL----APEETADYPIEKAVEAFCEGKFIGGP 204 Query: 163 WFDHIHG-WMPMREEKN-FLLLSYEELKQDTGRTIEKICQFLGKTL-EPEELNLILKNSS 219 ++DHI W RE N L ++YEELK+ T +++I +FL E EE+ I+K S Sbjct: 205 FWDHILEYWYASRENPNKVLFVTYEELKKQTEVEMKRIAEFLECGFIEEEEVREIVKLCS 264 Query: 220 FQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLP 278 F+S+ +++ L ++ RKG G W++ + + AE+ D+ +EK Sbjct: 265 FESLSNLEVNKEGKLPNG--IETKTFFRKGEIGGWRDTLSESLAEEIDRTIEEKFKGSG 321 >1X8L-A nrPDB Length = 351 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 63/285 (22%), Positives = 123/285 (43%), Gaps = 42/285 (14%) Query: 31 VIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPW------------- 77 +R DV + +Y +SGT E++ L+ + + + ++ Sbjct: 60 PLRPTDVFVASYQRSGTTMTQELVWLIENDLNFEAAKTYMSLRYIYLDGFMIYDPEKQEE 119 Query: 78 ------------VESEIGYTALS-----------ETESPRLFSSHLPIQLFPKSFFSSKA 114 +E +G S R +HLP+ L P + Sbjct: 120 YNDILPNPENLDMERYLGLLEYSSRPGSSLLAAVPPTEKRFVKTHLPLSLMPPNMLD-TV 178 Query: 115 KVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMR 174 K++YL R+PRDV VS + + + + K ++++++E F +G +F+H+ R Sbjct: 179 KMVYLARDPRDVAVSSFHHARLLYLLNKQSNFKDFWEMFHRGLYTLTPYFEHVKEAWAKR 238 Query: 175 EEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKEN---KMSNY 231 + N L L YE+ +D +I +I FLGK L E++ + ++ +F+ K N M +Y Sbjct: 239 HDPNMLFLFYEDYLKDLPGSIARIADFLGKKLSEEQIQRLSEHLNFEKFKNNGAVNMEDY 298 Query: 232 SLLSVDYVVDKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMAD 276 + + + D +RKG +G W+++F + +K ++ + D Sbjct: 299 REIGI--LADGEHFIRKGKAGCWRDYFDEEMTKQAEKWIKDNLKD 341 >3MGC-A nrPDB Length = 319 Score = 180 bits (456), Expect = 8e-46, Method: Composition-based stats. Identities = 57/267 (21%), Positives = 104/267 (38%), Gaps = 38/267 (14%) Query: 38 IILTYPKSGTNWLAEILCLMHSKGDAKWIQSVP-IWERSPWVESEIGYTALSETE--SPR 94 I +YPK+G W+ C++ + K Q I S +E+ + + L E P Sbjct: 40 WIASYPKAGNTWVR---CMLAAYITGKAPQVWNDIDAESLTLEAMLRFGDLPPAEPMEPV 96 Query: 95 LFSSHLPIQLFPKSFF-SSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWF 153 L +HL + + + AKV+YL+RNPRD+L+S + + ++ F Sbjct: 97 LVKTHLKADVPVLGLYGEATAKVLYLVRNPRDMLLSSMRMASISR--DDVEKSRDFARKF 154 Query: 154 CQGTVLYG-------------SWFDHIHGWMPMREEK----NFLLLSYEELKQDTGRTIE 196 G SW +++ W ++ + L + YE+LK D Sbjct: 155 IANE-GLGWNALGAGGGVGLGSWPENVRSWTESSSDRFPNADVLTMRYEDLKGDPVARFS 213 Query: 197 KICQF--LGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDW 254 +I +F LG ++ E++ + S+ + M+E + + + + KG G Sbjct: 214 EIVEFLDLGGPVDIEDIRRAVAASTLERMRELEKRSEQQGGGSPIRHGDARMMKGGPGGA 273 Query: 255 KNHFTVA---------QAEDFDKLFQE 272 + F ED + +QE Sbjct: 274 RPQFVGEGRYDQSLSFLGEDIESDYQE 300 >4EEC-A nrPDB Length = 286 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 49/207 (23%), Positives = 88/207 (42%), Gaps = 18/207 (8%) Query: 33 RDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVP-IWERSPWVESEI--GYTALSE 89 R I +YPK+G +WL C++ S + +++ P I P +E + G ++ Sbjct: 17 RGSMCWIASYPKAGGHWLR---CMLTSYVTGEPVETWPGIQAGVPHLEGLLRDGEAPSAD 73 Query: 90 TESPRLFSSHLPIQLFPKSFF-SSKAKVIYLMRNPRDVLVSGYFFWKNMKF-IKKPKSWE 147 + L ++H F+ S AKV+ L+RNPRD ++S ++ + Sbjct: 74 PDEQVLLATHFTADRPVLRFYRESTAKVVCLIRNPRDAMLSLMRMKGIPPEDVEACRKIA 133 Query: 148 EYF---EWFCQGTVLYG--SWFDHIHGWM----PMREEKNFLLLSYEELKQDTGRTIEKI 198 E F E F + G SW ++I W L + YE+L++D + K+ Sbjct: 134 ETFIADEGFSSVRIWAGEGSWPENIRSWTDSVHESFPNAAVLAVRYEDLRKDPEGELWKV 193 Query: 199 CQFLGKTLEPEELNLILKNSSFQSMKE 225 FL + + + N + + M+E Sbjct: 194 VDFLELG-GRDGVADAVANCTLERMRE 219 >3NIB-A nrPDB Length = 309 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 50/208 (24%), Positives = 89/208 (42%), Gaps = 21/208 (10%) Query: 38 IILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPW-VESEI--GYTALSETESPR 94 I +YPK+G WL C++ + K Q+ E +E + G +E P Sbjct: 40 WIASYPKAGNTWLR---CMLAAYITGKAPQTWKDMETVSLELEGMLHLGDMPPTEPTKPV 96 Query: 95 LFSSHLPIQLFPKSFF-SSKAKVIYLMRNPRDVLVSGYFFW--------KNMKFIKKPKS 145 L +HL + + + AKV+YL+RNPRD+L+S + F + + Sbjct: 97 LVKTHLKADVPVLGLYSEATAKVLYLVRNPRDILLSAMRMTAISRDDMESSRTFARDFIA 156 Query: 146 WEEYFEWFCQGTVLYGSWFDHIHGWMPMREEK----NFLLLSYEELKQDTGRTIEKICQF 201 E G GSW +++ W ++ + L + YE+LK D +I +F Sbjct: 157 NEGLRMRGRGGGAGLGSWPENVRIWTESSRDRFPNADVLTMRYEDLKGDPVARFSEIVEF 216 Query: 202 --LGKTLEPEELNLILKNSSFQSMKENK 227 LG ++ E++ + + + M+E + Sbjct: 217 LDLGDPVDIEDIRRAVAACTLERMRELE 244 >4GBM-A nrPDB Length = 323 Score = 50.8 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 20/169 (11%) Query: 54 LCLMHSKGDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFS-- 111 + DA Q++ S + + Y L E +PRL P + Sbjct: 91 TFMEVKNLDATASQALIKDLESQNLSIQQVYGMLQENIAPRLLVDKSPTYAMEPTILERG 150 Query: 112 ----SKAKVIYLMRNPRDVLVSGYFFWKNMK----FIKKPKSWEEYFEWFCQGTVLYGSW 163 + +K IYL+R+P V+ S + K + P E V S Sbjct: 151 EALFANSKYIYLVRHPYSVIESFVRM-RMQKLVGLGEENPYRVAE--------QVWAKS- 200 Query: 164 FDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELN 212 +I ++ E + + YE+L + + + ++C FL EPE L Sbjct: 201 NQNILNFLSQLEPERQHQIRYEDLVKKPQQVLSQLCDFLNVPFEPELLQ 249 >1T8T-A nrPDB Length = 271 Score = 46.6 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 26/131 (19%), Positives = 46/131 (35%), Gaps = 19/131 (14%) Query: 108 SFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWF--- 164 S S K+I ++R+P +S Y + + ++E ++ SW Sbjct: 95 SAMSKDTKLIVVVRDPVTRAISDYTQTLSKR--PDIPTFESLTFKNRTAGLIDTSWSAIQ 152 Query: 165 -----DHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLIL--KN 217 H+ W+ + L +S E L D + ++ FLG L I+ K+ Sbjct: 153 IGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLG-------LKRIITDKH 205 Query: 218 SSFQSMKENKM 228 F K Sbjct: 206 FYFNKTKGFPC 216 >4GOX-A nrPDB Length = 313 Score = 41.9 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 41/104 (39%), Gaps = 14/104 (13%) Query: 113 KAKVIYLMRNPRDVLVSGYFFWKNMKFI----KKPKSWEEYFEWFCQGTVLYGSWFDHIH 168 +AK I+L+R+P ++ + + K + + P + E +I Sbjct: 148 QAKYIHLVRHPY-AVIESFTRLRMDKLLGAEQQNPYALAESIWRTSN---------RNIL 197 Query: 169 GWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELN 212 +L + YE+L +D + + IC FLG + LN Sbjct: 198 DLGRTVGADRYLQVIYEDLVRDPRKVLTNICDFLGVDFDEALLN 241 >3RNL-A nrPDB Length = 311 Score = 38.8 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 44/103 (42%), Gaps = 8/103 (7%) Query: 113 KAKVIYLMRNPRDVLVS-GYFFWKNMK-FIKKPKSWEEYFEWFCQ--GTVLY----GSWF 164 AK++ ++RNP D S ++ + + +S + E Q + Y G + Sbjct: 109 DAKILIMLRNPVDRAFSAYMHLVRDERETLSFRESLAKEEERIRQHYEPLWYYRAVGLYA 168 Query: 165 DHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLE 207 + ++ + + ++ +EE +D + + C FLG + + Sbjct: 169 AQVKRYLDVFGREQVKVILFEEFARDPVQVVRDCCAFLGVSTD 211 >1NST-A nrPDB Length = 325 Score = 36.9 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 35/207 (16%), Positives = 70/207 (33%), Gaps = 34/207 (16%) Query: 24 RKVRDEFVIRDEDVIILTYPKSGTNWLAEIL----CLMHSKGDAKWIQSVPIWERSPWVE 79 K D F ++I+ K+GT L L L + ++ + + + + + Sbjct: 41 EKTCDRFP----KLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHK 96 Query: 80 SEIGYTALSETESPRLF-------SSHLPIQLFP--KSFFSSKAKVIYLMRNPRDVLVSG 130 Y S +++ ++ P + KAKV+ ++ NP D S Sbjct: 97 GIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSW 156 Query: 131 YFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGS-------------WF-DHIHGWMPMREE 176 Y + P + + F S W+ HI W+ Sbjct: 157 YQHQR---AHDDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHA 213 Query: 177 KNFLLLSYEELKQDTGRTIEKICQFLG 203 L+L + L+ + + ++ + +FLG Sbjct: 214 NQILVLDGKLLRTEPAKVMDMVQKFLG 240 >3WO8-A nrPDB Length = 478 Score = 34.2 bits (77), Expect = 0.060, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 45/107 (42%), Gaps = 15/107 (14%) Query: 52 EILCLMHSKGDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFS 111 +I ++ + + + + + +VE ++ + +++ + + +HL P Sbjct: 380 QIPEIVSRFFEVENVVRYTVEDGPEFVEGDLIFDFVADIPNEKALKAHLS---LPAE--- 433 Query: 112 SKAKVIY-LMRNPRDVLVSGYFFWKNMKFIK--KPKSWEEYFEWFCQ 155 K +Y ++RNP DV YF + + + KP S + E F Sbjct: 434 ---KTVYFVLRNPFDV---RYFEGRKIVVTRSTKPISIYKSLEHFLG 474 >3F5F-A nrPDB Length = 658 Score = 33.8 bits (76), Expect = 0.090, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 45/109 (41%), Gaps = 8/109 (7%) Query: 34 DEDVIILTY--PKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEIGYTALSETE 91 ++DV+I+ PK+ + I + +K + + + +P + + + Sbjct: 373 EDDVVIIYNRVPKTASTSFTNIAYDLCAKNRYHVLH-INTTKNNPVMSLQDQVRFVKNVT 431 Query: 92 S-----PRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWK 135 S P + H+ F K K I ++R+P + LVS Y+F + Sbjct: 432 SWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLR 480 >1ZRH-A nrPDB Length = 274 Score = 33.8 bits (76), Expect = 0.090, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 49/107 (45%), Gaps = 11/107 (10%) Query: 106 PKSFFSSK--AKVIYLMRNPRDVLVSGY---FFWKNMKFIKKPKSWEEYFEWFCQGTVLY 160 P+ +S +++ ++R+P + ++S Y F+ K P S EE+ + V Y Sbjct: 97 PERVYSMNPSIRLLLILRDPSERVLSDYTQVFYNHMQKHKPYP-SIEEFLVRDGRLNVDY 155 Query: 161 GS-----WFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFL 202 + + H+ W+ ++ ++ + L +D I+K+ +FL Sbjct: 156 KALNRSLYHVHMQNWLRFFPLRHIHIVDGDRLIRDPFPEIQKVERFL 202 >6DXU-D nrPDB Length = 830 Score = 31.1 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 31/99 (31%), Gaps = 9/99 (9%) Query: 186 ELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQL 245 + K + + ++K+ FL + +F ++K + + Sbjct: 495 DYKSISEQEMQKVKHFLHVEWGGDSHARRHSEDAFYNLKNIEAGKGGDERAGDASLYGGV 554 Query: 246 LRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPW 284 R GDW + V D +E+ E PW Sbjct: 555 PRASRDGDWSESYVVRL---IDWHLKEQ------ETMPW 584 >4WHN-A nrPDB Length = 183 Score = 30.4 bits (67), Expect = 0.90, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 30/78 (38%), Gaps = 7/78 (8%) Query: 151 EWFCQGTVLYGSWFDHIHGWMPMREE-KNFLLLSYEELKQDTGRTIEKICQFLGKTLEPE 209 WF + D + MR+ N L ++ D + KI +F G ++ + Sbjct: 100 RWFID---WIAPFGDSAALYKHMRDNFPNELF---RAIRVDPDSRVGKISEFHGGKIDKK 153 Query: 210 ELNLILKNSSFQSMKENK 227 + I + F+ M E K Sbjct: 154 LASKIFQQYHFELMSELK 171 >2EMT-A nrPDB Length = 322 Score = 30.4 bits (67), Expect = 0.90, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 29/70 (41%) Query: 185 EELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQ 244 +++K++ + +F + + E + I + F +KE +++ + V A Sbjct: 70 QDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLAS 129 Query: 245 LLRKGVSGDW 254 + GD+ Sbjct: 130 YAVQAKYGDY 139 >1X3Z-A nrPDB Length = 335 Score = 30.0 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 17/41 (41%) Query: 219 SFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHFT 259 + + K N+ N + K RKG G+W N FT Sbjct: 152 TVEIYKCNRCGNITRFPRYNDPIKLLETRKGRCGEWCNLFT 192 >1WZ2-A nrPDB Length = 967 Score = 29.2 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 30/84 (35%), Gaps = 12/84 (14%) Query: 118 YLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEW-FCQGTVLYGSWFDHIHGWMPMREE 176 Y++R DV V F P EE +E +G V W + + W E Sbjct: 781 YVLRTLADVWVRL-----MAPF--TPHICEELWEKLGGEGFVSLAKWPEPVEEWWNETIE 833 Query: 177 KNFLLLS--YEELKQDTGRTIEKI 198 + E++K+ + KI Sbjct: 834 AEEEFIRSVMEDIKE--IIEVAKI 855 >3K8L-A nrPDB Length = 669 Score = 28.8 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 7/23 (30%), Positives = 11/23 (47%) Query: 165 DHIHGWMPMREEKNFLLLSYEEL 187 HI+ E FL + YE++ Sbjct: 368 KHIYHSETSEENPRFLKMFYEDM 390 >1E5W-A nrPDB Length = 346 Score = 28.8 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 10/69 (14%), Positives = 29/69 (42%) Query: 185 EELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQ 244 +++++++ + +F + + E + I + F +KE +++ + V A Sbjct: 68 QDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLAS 127 Query: 245 LLRKGVSGD 253 + GD Sbjct: 128 YAVQSKYGD 136 >4YL8-A nrPDB Length = 303 Score = 28.8 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 10/69 (14%), Positives = 29/69 (42%) Query: 185 EELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQ 244 +++++++ + +F + + E + I + F +KE +++ + V A Sbjct: 74 QDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLAS 133 Query: 245 LLRKGVSGD 253 + GD Sbjct: 134 YAVQSKYGD 142 >6AGH-A nrPDB Length = 339 Score = 28.8 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 31/92 (33%), Gaps = 6/92 (6%) Query: 185 EELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQ 244 E + ++ +F GK L F+ EN + + Sbjct: 163 EAIVKEPEINTTLQMRFFGKRG-----QRKLHYKEFRRFMENLQTEIQEMEFLQFSKGLS 217 Query: 245 LLRKGVSGDWKNHFTVAQAEDFD-KLFQEKMA 275 +RK +W FT + +D K +EK++ Sbjct: 218 FMRKEDFAEWLLFFTNTENKDIYWKNVREKLS 249 >4RM9-A nrPDB Length = 587 Score = 28.4 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 28/70 (40%) Query: 185 EELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQ 244 +E++++ + +F + + E + I + F +KE +S+ + V Sbjct: 69 QEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGS 128 Query: 245 LLRKGVSGDW 254 + GD+ Sbjct: 129 YAVQAKFGDY 138 >4RMA-A nrPDB Length = 296 Score = 28.4 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 28/70 (40%) Query: 185 EELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQ 244 +E++++ + +F + + E + I + F +KE +S+ + V Sbjct: 68 QEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGS 127 Query: 245 LLRKGVSGDW 254 + GD+ Sbjct: 128 YAVQAKFGDY 137 >3AP1-A nrPDB Length = 337 Score = 28.1 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 15/32 (46%) Query: 180 LLLSYEELKQDTGRTIEKICQFLGKTLEPEEL 211 L + YE+L R+++ I FLG L Sbjct: 212 LPVYYEQLVLHPRRSLKLILDFLGIAWSDAVL 243 >1PQU-A nrPDB Length = 371 Score = 28.1 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 36/89 (40%), Gaps = 8/89 (8%) Query: 197 KICQFLG--KTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDW 254 K F+G + ++ + + + F+++ N + KA + +GD Sbjct: 2 KNVGFIGWRGMVGSVLMDRMSQENDFENL------NPVFFTTSQAGQKAPVFGGKDAGDL 55 Query: 255 KNHFTVAQAEDFDKLFQEKMADLPRELFP 283 K+ F + + + D + + D E++P Sbjct: 56 KSAFDIEELKKLDIIVTCQGGDYTNEVYP 84 >2GLJ-A nrPDB Length = 461 Score = 28.1 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 27/63 (42%), Gaps = 4/63 (6%) Query: 212 NLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHF--TVAQAEDFDKL 269 + I +SF++M E M N + +VDK ++ G +G F TVA Sbjct: 262 DRICAYTSFEAMLE--MKNAKKTCITILVDKEEVGSIGATGMQSKFFENTVADIMSLCGD 319 Query: 270 FQE 272 + E Sbjct: 320 YDE 322 >5Y81-H nrPDB Length = 279 Score = 27.7 bits (60), Expect = 5.8, Method: Composition-based stats. Identities = 9/67 (13%), Positives = 31/67 (46%), Gaps = 9/67 (13%) Query: 182 LSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVD 241 ++YE++K +T ++ ++ L K++ + ++ ++ ++ + + D Sbjct: 219 INYEDIKNETPGSVHELQLILQKSITDGVMRKVIGTDDWKLARQVQFE---------LDD 269 Query: 242 KAQLLRK 248 Q +R+ Sbjct: 270 TVQFMRR 276 >6EAZ-A nrPDB Length = 379 Score = 27.7 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 23/68 (33%), Gaps = 5/68 (7%) Query: 199 CQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHF 258 +F GK E + L F+ EN + + +RK +W F Sbjct: 180 VRFFGKRGEKK-----LHYKEFRRFMENLQTEVQEMEFLQFSKGLNFMRKEDFAEWLLFF 234 Query: 259 TVAQAEDF 266 T + +D Sbjct: 235 TNTENKDI 242 >5HFU-A nrPDB Length = 923 Score = 27.3 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 7/55 (12%), Positives = 17/55 (30%) Query: 210 ELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHFTVAQAE 264 + + M+ ++ + ++ G D++ F VA E Sbjct: 683 IVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDDFRTEFDVAVDE 737 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.138 0.416 Lambda K H 0.267 0.0429 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,253,899 Number of Sequences: 36641 Number of extensions: 495470 Number of successful extensions: 1576 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 60 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 1410 Number of HSP's gapped (non-prelim): 96 length of query: 285 length of database: 10,336,785 effective HSP length: 96 effective length of query: 189 effective length of database: 6,819,249 effective search space: 1288838061 effective search space used: 1288838061 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.3 bits)