BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q06389 (190 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2JU0-A nrPDB 395 e-111 2L2E-A nrPDB 253 3e-68 2LCP-A nrPDB 243 4e-65 6EPA-A nrPDB 223 6e-59 1BJF-A nrPDB 207 3e-54 5M6C-E nrPDB 201 2e-52 5T7C-A nrPDB 199 4e-52 3DD4-A nrPDB 164 3e-41 1S1E-A nrPDB 162 1e-40 1S6C-A nrPDB 161 1e-40 2JUL-A nrPDB 161 2e-40 2I94-A nrPDB 145 7e-36 2D8N-A nrPDB 138 1e-33 1JBA-A nrPDB 114 3e-26 2NA0-A nrPDB 99 8e-22 2R2I-A nrPDB 96 1e-20 2E6W-A nrPDB 93 6e-20 2GGZ-A nrPDB 73 6e-14 4ORC-B nrPDB 70 6e-13 5B8I-B nrPDB 70 7e-13 1V1G-A nrPDB 69 1e-12 5YPX-A nrPDB 68 2e-12 4IL1-A nrPDB 68 2e-12 1DTL-A nrPDB 60 6e-10 2ZFD-A nrPDB 58 2e-09 1UHN-A nrPDB 58 2e-09 2L1W-A nrPDB 57 3e-09 2TN4-A nrPDB 55 1e-08 1TOP-A nrPDB 52 2e-07 4OY4-A nrPDB 50 7e-07 5JN2-A nrPDB 50 7e-07 1JC2-A nrPDB 49 1e-06 3EK4-A nrPDB 49 2e-06 2N6A-A nrPDB 49 2e-06 3WFN-B nrPDB 49 2e-06 6O20-F nrPDB 48 2e-06 4E53-A nrPDB 48 2e-06 3U0K-A nrPDB 48 3e-06 6HCS-A nrPDB 48 3e-06 2F2P-A nrPDB 47 3e-06 4I2Y-A nrPDB 47 4e-06 3HZT-A nrPDB 47 4e-06 5UKG-A nrPDB 47 5e-06 3KHE-A nrPDB 47 5e-06 5A2H-A nrPDB 47 6e-06 2LM5-A nrPDB 46 1e-05 3K21-A nrPDB 45 2e-05 3QRX-A nrPDB 45 2e-05 5I0I-E nrPDB 45 2e-05 3L19-A nrPDB 45 2e-05 2E30-A nrPDB 44 3e-05 2M97-A nrPDB 44 4e-05 1LKJ-A nrPDB 44 4e-05 3LIJ-A nrPDB 44 4e-05 4RGJ-A nrPDB 44 4e-05 2LHI-A nrPDB 44 4e-05 2LHH-A nrPDB 44 5e-05 4JWQ-A nrPDB 44 5e-05 4YZB-A nrPDB 44 6e-05 2LC5-A nrPDB 43 7e-05 1GGZ-A nrPDB 43 7e-05 1OZS-A nrPDB 43 8e-05 3Q5I-A nrPDB 43 9e-05 2KSZ-A nrPDB 43 1e-04 4DS7-A nrPDB 43 1e-04 2BEC-A nrPDB 42 2e-04 5ZGM-A nrPDB 42 2e-04 3O4Y-A nrPDB 42 2e-04 3NCG-A nrPDB 42 2e-04 1CLM-A nrPDB 42 2e-04 1YX7-A nrPDB 41 2e-04 5E37-A nrPDB 41 3e-04 2LV7-A nrPDB 41 3e-04 2AAO-A nrPDB 41 3e-04 1S6I-A nrPDB 41 4e-04 5MWC-D nrPDB 40 8e-04 2LMV-A nrPDB 39 0.001 2M29-A nrPDB 38 0.002 2HF5-A nrPDB 38 0.002 2ROB-A nrPDB 38 0.003 2RO9-A nrPDB 38 0.003 5PAL-A nrPDB 38 0.003 3KF9-A nrPDB 38 0.003 2KN2-A nrPDB 38 0.003 5COC-A nrPDB 38 0.003 3IFK-A nrPDB 37 0.004 2JNX-A nrPDB 37 0.004 2BL0-C nrPDB 37 0.006 2LAP-A nrPDB 37 0.006 3E3R-A nrPDB 37 0.006 5H7D-E nrPDB 37 0.007 2RO8-A nrPDB 37 0.008 2OBH-A nrPDB 36 0.008 2I08-A nrPDB 36 0.008 2GGM-A nrPDB 36 0.008 4Q57-A nrPDB 36 0.008 3MSE-B nrPDB 36 0.008 4BTS-A7 nrPDB 36 0.009 1FW4-A nrPDB 36 0.012 2M5E-A nrPDB 35 0.014 1JFJ-A nrPDB 35 0.023 6OKK-O nrPDB 34 0.033 1F55-A nrPDB 34 0.038 3I5H-B nrPDB 34 0.039 4NQG-A nrPDB 34 0.045 5ZOR-A nrPDB 34 0.045 2B1U-A nrPDB 33 0.061 1NYA-A nrPDB 33 0.061 4N5X-A nrPDB 33 0.076 4ZCV-A nrPDB 33 0.079 2JNF-A nrPDB 33 0.082 1JF0-A nrPDB 33 0.085 5ZH6-A nrPDB 33 0.10 1TIZ-A nrPDB 33 0.10 2HPS-A nrPDB 33 0.10 2KZ2-A nrPDB 32 0.12 2OPO-A nrPDB 32 0.13 5VE9-A nrPDB 32 0.13 1TNP-A nrPDB 32 0.16 3JAX-C nrPDB 32 0.16 1RTP-1 nrPDB 32 0.18 1C7W-A nrPDB 32 0.19 1SL8-A nrPDB 32 0.20 1TRF-A nrPDB 32 0.21 1G33-A nrPDB 32 0.21 5XND-A nrPDB 32 0.23 1BU3-A nrPDB 31 0.25 1S36-A nrPDB 31 0.26 3J04-B nrPDB 31 0.26 3FWC-A nrPDB 31 0.26 3KPX-A nrPDB 31 0.27 4MSP-A nrPDB 31 0.30 2SAS-A nrPDB 31 0.37 1A75-A nrPDB 31 0.37 4P5W-A nrPDB 31 0.41 1UHK-A nrPDB 31 0.42 5XOP-A nrPDB 30 0.53 1SJJ-A nrPDB 30 0.55 2L50-A nrPDB 30 0.59 1OQP-A nrPDB 30 0.60 5ZI5-A nrPDB 30 0.64 1W7I-B nrPDB 30 0.69 1RK9-A nrPDB 30 0.71 5OTJ-D nrPDB 30 0.71 4P5X-A nrPDB 30 0.77 3JBH-C nrPDB 30 0.79 2NCO-A nrPDB 30 0.87 2G9B-A nrPDB 30 0.87 3AAJ-A nrPDB 29 0.94 4WPX-A nrPDB 29 0.95 2AMI-A nrPDB 29 0.95 2M1U-A nrPDB 29 0.98 2K2A-A nrPDB 29 1.0 1DGU-A nrPDB 29 1.0 5H53-C nrPDB 29 1.1 2K7B-A nrPDB 29 1.1 2I18-A nrPDB 29 1.2 1S6J-A nrPDB 29 1.3 1IJ5-A nrPDB 29 1.3 2N7L-C nrPDB 29 1.3 2N8Y-A nrPDB 29 1.4 2KQY-A nrPDB 28 1.7 1KYW-A nrPDB 28 1.8 1H4B-A nrPDB 28 1.8 1CB1-A nrPDB 28 1.9 5Z1Q-A nrPDB 28 2.1 1Y1X-A nrPDB 28 2.3 2Q4U-A nrPDB 28 2.3 2JXC-A nrPDB 28 2.5 1BOD-A nrPDB 28 2.7 6D6R-C nrPDB 28 2.7 3PAT-A nrPDB 28 2.9 5JOJ-A nrPDB 28 3.0 2LVK-A nrPDB 28 3.1 4D1E-A nrPDB 28 3.2 1SR6-C nrPDB 28 3.4 4L9M-A nrPDB 28 3.4 5JOL-A nrPDB 28 3.4 2BL0-B nrPDB 27 3.6 3CS1-A nrPDB 27 3.7 6IIE-A nrPDB 27 4.1 2JOJ-A nrPDB 27 4.2 3A8R-A nrPDB 27 4.5 4OCI-A nrPDB 27 4.8 5VLN-A nrPDB 27 5.1 2VRG-A nrPDB 27 5.1 4GJF-A nrPDB 27 5.4 3LCP-C nrPDB 27 5.6 4PAL-A nrPDB 27 6.0 3A4U-B nrPDB 27 6.1 3I6D-A nrPDB 27 6.8 3SIA-A nrPDB 27 6.9 5DGE-C0 nrPDB 27 7.2 4YGB-B nrPDB 26 8.3 4MVF-A nrPDB 26 9.0 1Q80-A nrPDB 26 9.9 >2JU0-A nrPDB Length = 190 Score = 395 bits (1014), Expect = e-111, Method: Compositional matrix adjust. Identities = 190/190 (100%), Positives = 190/190 (100%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS Sbjct: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE Sbjct: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII Sbjct: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 Query: 181 GALNLYDGLI 190 GALNLYDGLI Sbjct: 181 GALNLYDGLI 190 >2L2E-A nrPDB Length = 190 Score = 253 bits (647), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 118/189 (62%), Positives = 149/189 (78%) Query: 2 GAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP 61 G SKLS+D L L +ST FD++E+QQW+KGF +DCPSG L + +F KIYKQFFPFG P Sbjct: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 FA ++F VFD D NG+I F+EFI LS TSRG L +KL WAF+LYDL+++G I++DEM Sbjct: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIG 181 L IV ++YKM+GSMV L EDE TPE RV KIF +MDKN+DG +TL+EF EGSK DP+I+ Sbjct: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 Query: 182 ALNLYDGLI 190 AL+LYDGL+ Sbjct: 182 ALSLYDGLV 190 >2LCP-A nrPDB Length = 190 Score = 243 bits (619), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 114/190 (60%), Positives = 144/190 (75%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 MG SKL + + L + TYF +E+QQW+KGF++DCPSGQL F KIYKQFFPFG Sbjct: 1 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 60 Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 P FA +F VFD++ +G I F EFI LS TSRGTL+EKL WAF+LYDL++DGYIT +E Sbjct: 61 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 120 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 ML IV ++Y+M+G+ V L E+E TPE RV +IF +MDKN DG +TL EF+EGSK DPSI+ Sbjct: 121 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIV 180 Query: 181 GALNLYDGLI 190 AL+LYDGL+ Sbjct: 181 QALSLYDGLV 190 >6EPA-A nrPDB Length = 187 Score = 223 bits (567), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 107/185 (57%), Positives = 135/185 (72%), Gaps = 1/185 (0%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 MG K SKL +D + L TYF +EI+QWHKGFL+DCP+G L + F+KIYKQFFP G Sbjct: 1 MGKKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGD 60 Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 P FA+ +F VFD++N+G I FEEFI LS TSRG L+EKL WAF LYD+++DGYIT +E Sbjct: 61 PSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREE 120 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 M IV ++Y+M+G EDE TP+ RV KIF MDKN D +TL+EFREGSK DP ++ Sbjct: 121 MYNIVDAIYQMVGQQPQ-TEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMV 179 Query: 181 GALNL 185 AL+L Sbjct: 180 QALSL 184 >1BJF-A nrPDB Length = 193 Score = 207 bits (526), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 98/184 (53%), Positives = 129/184 (70%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 MG + SKL + + L +ST F EIQ+W+KGFLRDCPSG L+ E+F KIY FFP+G Sbjct: 1 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD 60 Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 FA H+F FD + +G I F EFI LS TSRG LE+KL WAF +YDL+ +GYI+ E Sbjct: 61 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE 120 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 ML IV ++YKM+ S++ + EDE+TPE R +KIF+ MD N DG ++L+EF G+K DPSI+ Sbjct: 121 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIV 180 Query: 181 GALN 184 L Sbjct: 181 RLLQ 184 >5M6C-E nrPDB Length = 193 Score = 201 bits (510), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 94/183 (51%), Positives = 131/183 (71%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 MG + SKL + L L+++T F E+Q+W+KGFL+DCP+G L ++F KIY FFP+G Sbjct: 1 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGD 60 Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 FA H+F FD +++G I F EFI LS TSRG LE+KL WAF +YDL+ +GYI+ +E Sbjct: 61 ASKFAEHVFRNFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREE 120 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 ML IV ++YKM+ S++ + EDE+TPE R +KIF+ MD N DG ++L+EF G+K DPSI+ Sbjct: 121 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV 180 Query: 181 GAL 183 L Sbjct: 181 RLL 183 >5T7C-A nrPDB Length = 193 Score = 199 bits (507), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 93/183 (50%), Positives = 127/183 (69%) Query: 2 GAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP 61 G + SKL + L L+++T F E+Q+W+KGFL+DCP+G L ++F KIY FFP+G Sbjct: 2 GKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDA 61 Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 FA H+F FD + +G I F EFI LS TSRG LE+KL WAF +YDL+ +GYI+ EM Sbjct: 62 SKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEM 121 Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIG 181 L IV ++YKM+ S++ + EDE+TPE R KIF+ MD N DG ++L+EF G+K DPSI+ Sbjct: 122 LEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVR 181 Query: 182 ALN 184 L Sbjct: 182 LLQ 184 >3DD4-A nrPDB Length = 229 Score = 164 bits (414), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 80/186 (43%), Positives = 118/186 (63%) Query: 5 TSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDF 64 T + + L L+ + F ++E+Q ++GF +CPSG + E F +IY QFFP G + Sbjct: 44 TVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTY 103 Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A+ LF FD D+NG + FE+FI LS RGT++EKL+WAF LYD+N DGYIT +EML I Sbjct: 104 AHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDI 163 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALN 184 + ++Y MMG E P V+ F+ MDKN+DG +T+DEF E + D +I+ ++ Sbjct: 164 MKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQ 223 Query: 185 LYDGLI 190 L++ +I Sbjct: 224 LFENVI 229 >1S1E-A nrPDB Length = 224 Score = 162 bits (409), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 79/178 (44%), Positives = 109/178 (61%) Query: 13 LTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVF 72 L L+ T F +RE+Q ++GF +CPSG + E F +IY QFFP G +A++LF F Sbjct: 39 LEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAF 98 Query: 73 DKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 D G + FE+F+T LS RGT+ EKL W F LYD+N DGYI +EM+ IV ++Y MM Sbjct: 99 DTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMM 158 Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI 190 G E TP V F+ MDKN+DG +TLDEF E + D +I+ +L L+ ++ Sbjct: 159 GKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM 216 >1S6C-A nrPDB Length = 183 Score = 161 bits (408), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 79/178 (44%), Positives = 109/178 (61%) Query: 13 LTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVF 72 L L+ T F +RE+Q ++GF +CPSG + E F +IY QFFP G +A++LF F Sbjct: 6 LEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAF 65 Query: 73 DKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 D G + FE+F+T LS RGT+ EKL W F LYD+N DGYI +EM+ IV ++Y MM Sbjct: 66 DTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMM 125 Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI 190 G E TP V F+ MDKN+DG +TLDEF E + D +I+ +L L+ ++ Sbjct: 126 GKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM 183 >2JUL-A nrPDB Length = 256 Score = 161 bits (407), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 79/186 (42%), Positives = 115/186 (61%) Query: 5 TSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDF 64 T + + L L+ T F ++E+Q ++GF +CP+G + + F IY QFFP G + Sbjct: 71 TVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTY 130 Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A+ LF FD D NG IHFE+F+ LS RGT+ EKL WAF LYD+N DG IT +EML I Sbjct: 131 AHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALN 184 + S+Y MMG E P V++ F+ MD+N+DG +T+DEF E + D +I+ ++ Sbjct: 191 MKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 Query: 185 LYDGLI 190 L++ +I Sbjct: 251 LFENVI 256 >2I94-A nrPDB Length = 202 Score = 145 bits (367), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 73/183 (39%), Positives = 116/183 (63%), Gaps = 3/183 (1%) Query: 1 MG-AKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFG 59 MG +K+ LSK+ L L+ +T F E+ W++ FL++CPSG++ R++F IY +FFP Sbjct: 1 MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEA 60 Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 P+ +A H+F FD +++G + F+E++ L TS G +KL WAF LYD++ +G I+ + Sbjct: 61 DPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKN 120 Query: 120 EMLTIVASVYKMMGSMVT--LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDP 177 E+L IV +++KM+ T L EDE TPE R +KI+ K +D +T EF EG+ + Sbjct: 121 EVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIEGTLANK 180 Query: 178 SII 180 I+ Sbjct: 181 EIL 183 >2D8N-A nrPDB Length = 207 Score = 138 bits (348), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 68/175 (38%), Positives = 111/175 (63%), Gaps = 2/175 (1%) Query: 8 LSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANH 67 LSK+ L L+ +T F E+ W++ FL+DCP+G++ ++ F IY +FFP P+ +A H Sbjct: 16 LSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQH 75 Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 +F FD + +G + F+E++ L T+ G +KL WAF LYD++ +G I+ +E+L IV + Sbjct: 76 VFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMA 135 Query: 128 VYKMMGS--MVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 ++KM+ + L +DE TPE R +KI+K KN+D +T EF EG+ + I+ Sbjct: 136 IFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEIL 190 >1JBA-A nrPDB Length = 204 Score = 114 bits (284), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 63/171 (36%), Positives = 98/171 (57%), Gaps = 12/171 (7%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPED---FANHLFTVFDKDNNGF 79 D ++Q+W+K FL +CPSG L F+ +K+FF E+ + +F FD + + Sbjct: 20 DAAQLQEWYKKFLEECPSGTL----FMHEFKRFFKVPDNEEATQYVEAMFRAFDTNGDNT 75 Query: 80 IHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLN 139 I F E++ L+ RGTLE KL W F++YD + +G I E+L IV S+YK+ + Sbjct: 76 IDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEV 135 Query: 140 EDEA-----TPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNL 185 E E TPE V +IF L+D+N DG ++L+EF EG++ D ++ L + Sbjct: 136 EAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKMLQM 186 >2NA0-A nrPDB Length = 205 Score = 99.4 bits (246), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 54/160 (33%), Positives = 90/160 (56%), Gaps = 8/160 (5%) Query: 26 EIQQWHKGFLRDCPSGQLAREDFVKIY--KQFFPFGSPEDFANHLFTVFDKDNNGFIHFE 83 E QW+K F+ +CPSGQL +F + + K P+ S + +F FD + +G+I F Sbjct: 17 ECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPWASQ--YVEQMFETFDFNKDGYIDFM 74 Query: 84 EFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEA 143 E+ LS +G +E+KL W F+LYD++ +G I DE+LTI+ ++ ++ ++ Sbjct: 75 EYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIR----AINPCSDSTM 130 Query: 144 TPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGAL 183 T E +F +D N DG ++L+EF EG + D ++ L Sbjct: 131 TAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTL 170 >2R2I-A nrPDB Length = 198 Score = 95.5 bits (236), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 53/162 (32%), Positives = 86/162 (53%), Gaps = 13/162 (8%) Query: 26 EIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFG----SPEDFANHLFTVFDKDNNGFIH 81 E QW+K F+ +CPSGQL +F KQFF S + +F FD + +G+I Sbjct: 15 ECHQWYKKFMTECPSGQLTLYEF----KQFFGLKNLSPSANKYVEQMFETFDFNKDGYID 70 Query: 82 FEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNED 141 F E++ LS +G +++KL W F+LYD++ +G I E+L I+ ++ + + Sbjct: 71 FMEYVAALSLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAI-----RAINRCNE 125 Query: 142 EATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGAL 183 T E +F +D N DG ++L+EF EG + D ++ L Sbjct: 126 AMTAEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDIL 167 >2E6W-A nrPDB Length = 100 Score = 93.2 bits (230), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 43/96 (44%), Positives = 64/96 (66%) Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 GT+ EKL WAF LYD+N DGYIT +EML I+ S+Y MMG E P V++ F+ Sbjct: 5 GTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFE 64 Query: 155 LMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI 190 MD+N+DG +T++EF E + D +I+ ++ L++ +I Sbjct: 65 KMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI 100 >2GGZ-A nrPDB Length = 211 Score = 73.2 bits (178), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 42/156 (26%), Positives = 77/156 (49%), Gaps = 6/156 (3%) Query: 25 REIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE 84 +E W++ F+ + PSG +F + + ++ FD + +GF+ F E Sbjct: 19 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 78 Query: 85 FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEAT 144 FI ++ + +E+KL W F+LYD + +G I +E+L + +V + G + + Sbjct: 79 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG------QQTLS 132 Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 PE + +F +D N DG +TL+EF G D ++ Sbjct: 133 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 168 >4ORC-B nrPDB Length = 170 Score = 69.7 bits (169), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 52/178 (29%), Positives = 91/178 (51%), Gaps = 22/178 (12%) Query: 16 LKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 L+ ++FD EI++ K F L SG L+ E+F+ + P + +FD Sbjct: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 Query: 74 KDNNGFIHFEEFITVLSTTS-RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 D NG + F+EFI +S S +G E+KL +AF +YD++ DGYI+ E+ ++++ Sbjct: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL-------FQVL 116 Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI 190 MV N + + V K DK+ DG I+ +EF +++G L+++ ++ Sbjct: 117 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF-------CAVVGGLDIHKKMV 167 >5B8I-B nrPDB Length = 171 Score = 69.7 bits (169), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 52/166 (31%), Positives = 86/166 (51%), Gaps = 17/166 (10%) Query: 8 LSKDDLTCLKQSTYFDRREIQQWHKGFL---RDCPSGQLAREDFVKIYKQFFPFGSPEDF 64 +S L + + FD E+ + K F+ RD SG + R++F+ + P S Sbjct: 1 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRD-KSGTIERDEFLSL-----PQVSSNPL 54 Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 + + +FD+D G + F+EF++ LS +S+G EEKL +AF++YD++ DG+I+ E+ Sbjct: 55 STRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFI 114 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 V KM MV N + + V K D + DG I+ +EF Sbjct: 115 ----VLKM---MVGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEF 153 >1V1G-A nrPDB Length = 222 Score = 68.9 bits (167), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 43/123 (34%), Positives = 69/123 (56%), Gaps = 5/123 (4%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 FA+ +F VFD NG I F EF+ L + EK+ +AF+LYDL G+I +E+ Sbjct: 75 FADRIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELK 134 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGA 182 +V ++ + S + L+ED E+ V K F D+ DG I +DE+++ ++PS+I Sbjct: 135 EMVVAL--LHESELVLSED--MIEVMVDKAFVQADRKNDGKIDIDEWKDFVSLNPSLIKN 190 Query: 183 LNL 185 + L Sbjct: 191 MTL 193 >5YPX-A nrPDB Length = 223 Score = 68.2 bits (165), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 52/189 (27%), Positives = 93/189 (49%), Gaps = 19/189 (10%) Query: 1 MGAKTSKLSKD--DLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPF 58 M K KL+++ +C K T + + +K L ++ R F I Q F Sbjct: 21 MSKKNQKLAEELYKTSCQKHFTKTEVESLIICYKNLLEGL---KMDRNLFRDILHQ--KF 75 Query: 59 GSPEDF-ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYIT 117 ED + +F FDKD++ +I E++ LS RGTL+EK+ + F ++DLN DGYI+ Sbjct: 76 NMTEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLDEKMEYTFTVFDLNGDGYIS 135 Query: 118 FDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKI----FKLMDKNEDGYITLDEFREGS 173 +EM ++M+ + + E P+ +K + K MD + D ++ +F++ Sbjct: 136 REEM-------FQMLKTCLVKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKKDFKDAV 188 Query: 174 KVDPSIIGA 182 ++P ++ A Sbjct: 189 LIEPLLLEA 197 >4IL1-A nrPDB Length = 823 Score = 68.2 bits (165), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 52/178 (29%), Positives = 91/178 (51%), Gaps = 22/178 (12%) Query: 16 LKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 L+ ++FD EI++ K F L SG L+ E+F+ + P + +FD Sbjct: 166 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 220 Query: 74 KDNNGFIHFEEFITVLSTTS-RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 D NG + F+EFI +S S +G E+KL +AF +YD++ DGYI+ E+ ++++ Sbjct: 221 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL-------FQVL 273 Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI 190 MV N + + V K DK+ DG I+ +EF +++G L+++ ++ Sbjct: 274 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF-------CAVVGGLDIHKKMV 324 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 17 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 77 MK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 107 Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 12/131 (9%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F VFDKD NG+I E V++ +E++ D++ DG + ++E + ++ + Sbjct: 90 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149 Query: 129 YKMMGSMVTLNEDEATPEM----------RVKKIFKLMDKNEDGYITLDEFREGSKV--D 176 G NE EM R+ K FK +D + G ++++EF ++ + Sbjct: 150 GGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN 209 Query: 177 PSIIGALNLYD 187 P + ++++D Sbjct: 210 PLVQRVIDIFD 220 >1DTL-A nrPDB Length = 161 Score = 60.1 bits (144), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 43/162 (26%), Positives = 81/162 (50%), Gaps = 17/162 (10%) Query: 14 TCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 ++Q T + E + F+ G ++ ++ K+ + +PE+ + V D Sbjct: 7 AAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEV-D 65 Query: 74 KDNNGFIHFEEFITVLSTT----SRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 +D +G + F+EF+ ++ + S+G EE+LS F ++D N DGYI +E+ ++ + Sbjct: 66 EDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATG 125 Query: 130 KMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 + T+ ED+ ++++ K DKN DG I DEF E Sbjct: 126 E------TITEDD------IEELMKDGDKNNDGRIDYDEFLE 155 Score = 42.7 bits (99), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 36/70 (51%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 G E+ + LF +FDK+ +G+I EE +L T E+ + + D N+DG I + Sbjct: 91 GKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDY 150 Query: 119 DEMLTIVASV 128 DE L + V Sbjct: 151 DEFLEFMKGV 160 >2ZFD-A nrPDB Length = 226 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 37/123 (30%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 FA+ +F +FD +NG + FEEF LS +++K+ ++F+LYDL G+I E+ Sbjct: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGA 182 +V + G +N + E + K F+ D DG I +E+R PS++ Sbjct: 146 QMVVATLAESG----MNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKN 201 Query: 183 LNL 185 + L Sbjct: 202 MTL 204 >1UHN-A nrPDB Length = 189 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 13/180 (7%) Query: 12 DLTCLKQSTYFDRREIQQWHKGFLRDCPS----GQLAREDFVKIYKQFFPFGSPED-FAN 66 D L + T F EI+ ++ F + + G + +E+F F E FA+ Sbjct: 1 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEF---QLALFKTNKKESLFAD 57 Query: 67 HLFTVFDKDNNGFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 +F +FD +NG + FEEF LS +++K+ ++F+LYDL G+I E+ +V Sbjct: 58 RVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 117 Query: 126 ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNL 185 + G +N + E + K F+ D DG I +E+R PS++ + L Sbjct: 118 VATLAESG----MNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 173 >2L1W-A nrPDB Length = 149 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 34/102 (33%), Positives = 53/102 (51%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FDKD +G I EE TV+ + + EE+L D + +G I FDE L+++A Sbjct: 16 FGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLMAKK 75 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +K+ FK+ DK+++GYI+ E R Sbjct: 76 VK-----------DTDAEEELKEAFKVFDKDQNGYISASELR 106 Score = 46.2 bits (108), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 33/130 (25%), Positives = 64/130 (49%), Gaps = 14/130 (10%) Query: 41 GQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEE 99 G + E+ + + + E+ + + V D D NG I F+EF+++++ + T EE Sbjct: 25 GCITVEELATVIRSLDQNPTEEELQDMISEV-DADGNGTIEFDEFLSLMAKKVKDTDAEE 83 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 +L AF+++D + +GYI+ E+ V +N E + V+++ K D + Sbjct: 84 ELKEAFKVFDKDQNGYISASEL------------RHVMINLGEKLTDEEVEQMIKEADLD 131 Query: 160 EDGYITLDEF 169 DG + +EF Sbjct: 132 GDGQVNYEEF 141 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 21/89 (23%), Positives = 43/89 (48%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 +G + ++F+ + + E+ F VFDKD NG+I E V+ +E Sbjct: 60 NGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDE 119 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASV 128 ++ + DL+ DG + ++E + ++ +V Sbjct: 120 EVEQMIKEADLDGDGQVNYEEFVKMMMTV 148 >2TN4-A nrPDB Length = 159 Score = 55.5 bits (132), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 16/101 (15%) Query: 73 DKDNNGFIHFEEFITVL----STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 D+D +G I FEEF+ ++ ++G EE+L+ F ++D N DGYI +E+ A + Sbjct: 63 DEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEEL----AEI 118 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 ++ G VT E ++ + K DKN DG I DEF Sbjct: 119 FRASGEHVTDEE--------IESLMKDGDKNNDGRIDFDEF 151 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 8/103 (7%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FD D G I +E TV+ + +E+L E D + G I F+E L ++ Sbjct: 23 FDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQ 82 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 K + + E + ++F++ D+N DGYI +E E Sbjct: 83 MK--------EDAKGKSEEELAELFRIFDRNADGYIDAEELAE 117 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 36/70 (51%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 G E+ LF +FD++ +G+I EE + + +E++ + D N+DG I F Sbjct: 89 GKSEEELAELFRIFDRNADGYIDAEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDF 148 Query: 119 DEMLTIVASV 128 DE L ++ V Sbjct: 149 DEFLKMMEGV 158 >1TOP-A nrPDB Length = 162 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 33/101 (32%), Positives = 52/101 (51%), Gaps = 16/101 (15%) Query: 73 DKDNNGFIHFEEFITVL----STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 D+D +G I FEEF+ ++ ++G EE+L+ F ++D N DG+I +E+ + Sbjct: 66 DEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEEL----GEI 121 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + G VT E ++ + K DKN DG I DEF Sbjct: 122 LRATGEHVT--------EEDIEDLMKDSDKNNDGRIDFDEF 154 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Query: 40 SGQLAREDF----VKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRG 95 SG + E+F V+ K+ S E+ AN F +FDK+ +GFI EE +L T Sbjct: 70 SGTIDFEEFLVMMVRQMKEDAKGKSEEELAN-CFRIFDKNADGFIDIEELGEILRATGEH 128 Query: 96 TLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 EE + + D N+DG I FDE L ++ V Sbjct: 129 VTEEDIEDLMKDSDKNNDGRIDFDEFLKMMEGV 161 Score = 43.1 bits (100), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 8/103 (7%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FD D G I +E TV+ + +E+L E D + G I F+E L ++ Sbjct: 26 FDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQ 85 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 K + + E + F++ DKN DG+I ++E E Sbjct: 86 MK--------EDAKGKSEEELANCFRIFDKNADGFIDIEELGE 120 >4OY4-A nrPDB Length = 415 Score = 49.7 bits (117), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + DG I F E LT++A Sbjct: 24 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFLTMMARK 83 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 84 MK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 114 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 13/98 (13%) Query: 73 DKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 D D +G I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ + Sbjct: 64 DADGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTN---- 119 Query: 132 MGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 +G +T DE EM + D + DG + +EF Sbjct: 120 LGEKLT---DEEVDEM-----IREADIDGDGQVNYEEF 149 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 31/59 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F VFDKD NG+I E V++ +E++ D++ DG + ++E + ++ + Sbjct: 97 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 155 >5JN2-A nrPDB Length = 525 Score = 49.7 bits (117), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 40/143 (27%), Positives = 63/143 (44%), Gaps = 28/143 (19%) Query: 41 GQLAREDFVKIYKQFFPF----------GSPEDFANHLFTVFDKDNNGFIHFEEFITVLS 90 GQL R + ++ YK+ + E + + D D NG+I + EF+TV Sbjct: 391 GQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEFVTV-- 448 Query: 91 TTSRGTL--EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMR 148 R TL E+L AF ++D ++ G I+ E+ TI + D T Sbjct: 449 AMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFG----------VSDVDSET---- 494 Query: 149 VKKIFKLMDKNEDGYITLDEFRE 171 K + +DKN DG + DEF++ Sbjct: 495 WKSVLSEVDKNNDGEVDFDEFQQ 517 >1JC2-A nrPDB Length = 76 Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 27/69 (39%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 S E+ AN F +FDK+ +GFI EE +L T +EE + + D N+DG I FD Sbjct: 8 SEEELAN-CFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFD 66 Query: 120 EMLTIVASV 128 E L ++ V Sbjct: 67 EFLKMMEGV 75 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 12/77 (15%) Query: 93 SRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKI 152 ++G EE+L+ F ++D N DG+I +E+ I+ + E E ++ + Sbjct: 4 AKGKSEEELANCFRIFDKNADGFIDIEELGEILRATG------------EHVIEEDIEDL 51 Query: 153 FKLMDKNEDGYITLDEF 169 K DKN DG I DEF Sbjct: 52 MKDSDKNNDGRIDFDEF 68 >3EK4-A nrPDB Length = 451 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 319 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 378 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 379 MK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 409 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NG I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 354 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 413 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + +G +T DE EM + D + DG + +EF Sbjct: 414 N----LGEKLT---DEEVDEM-----IREADIDGDGQVNYEEF 444 Score = 35.8 bits (81), Expect = 0.010, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 31/59 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F VFDKD NG+I E V++ +E++ D++ DG + ++E + ++ + Sbjct: 392 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 450 >2N6A-A nrPDB Length = 173 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%) Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 16 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 75 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 76 RKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 108 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 34/74 (45%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 E+ F VFDKD NG+I E V++ +E++ D++ DG + ++E Sbjct: 83 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 142 Query: 121 MLTIVASVYKMMGS 134 + ++ GS Sbjct: 143 FVQMMTGASTAAGS 156 >3WFN-B nrPDB Length = 182 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 23 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 82 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 83 MK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 113 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NG I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 58 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 117 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + +G +T DE EM + D + DG + +EF Sbjct: 118 N----LGEKLT---DEEVDEM-----IREADIDGDGQVNYEEF 148 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 31/59 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F VFDKD NG+I E V++ +E++ D++ DG + ++E + ++ + Sbjct: 96 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 154 >6O20-F nrPDB Length = 169 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 37 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 96 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 97 MK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 127 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NG I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 72 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 131 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + +G +T E V ++ + D + DG + +EF Sbjct: 132 N----LGEKLTDEE--------VDEMIREADIDGDGQVNYEEF 162 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 31/59 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F VFDKD NG+I E V++ +E++ D++ DG + ++E + ++ + Sbjct: 110 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 168 >4E53-A nrPDB Length = 185 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 24 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 83 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 84 MK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 114 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NG I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 59 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 118 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + +G +T DE EM + D + DG + +EF Sbjct: 119 N----LGEKLT---DEEVDEM-----IREADIDGDGQVNYEEF 149 Score = 35.8 bits (81), Expect = 0.012, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 30/57 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F VFDKD NG+I E V++ +E++ D++ DG + ++E + ++ Sbjct: 97 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 >3U0K-A nrPDB Length = 442 Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + DG I F E L ++A Sbjct: 310 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFLIMMARK 369 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 370 MK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 400 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 13/98 (13%) Query: 73 DKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 D D +G I F EF+ +++ + T EE++ AF ++D + +GYI+ E+ ++ + Sbjct: 350 DADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTN---- 405 Query: 132 MGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 +G +T DE EM + D + DG + +EF Sbjct: 406 LGEKLT---DEEVDEM-----IREADIDGDGQVNYEEF 435 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 33/66 (50%) Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 E+ F VFDKD NG+I E V++ +E++ D++ DG + ++E Sbjct: 376 EEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 435 Query: 122 LTIVAS 127 + ++ + Sbjct: 436 VQMMTA 441 >6HCS-A nrPDB Length = 167 Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 17 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 77 MK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 107 Score = 33.1 bits (74), Expect = 0.065, Method: Compositional matrix adjust. Identities = 16/65 (24%), Positives = 32/65 (49%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F VFDKD NG+I E ++ +E++ D++ DG + ++E + ++ + Sbjct: 90 FRVFDKDGNGYISAAELRHFMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149 Query: 129 YKMMG 133 + G Sbjct: 150 LEGTG 154 >2F2P-A nrPDB Length = 179 Score = 47.4 bits (111), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 17 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 77 MK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 107 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NG I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 111 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + +G +T DE EM + D + DG + +EF Sbjct: 112 N----LGEKLT---DEEVDEM-----IREADIDGDGQVNYEEF 142 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 33/67 (49%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 E+ F VFDKD NG+I E V++ +E++ D++ DG + ++E Sbjct: 82 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 141 Query: 121 MLTIVAS 127 + ++ + Sbjct: 142 FVQMMTA 148 >4I2Y-A nrPDB Length = 421 Score = 47.4 bits (111), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + DG F E LT++A Sbjct: 289 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFLTMMAR- 347 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 +N+ ++ E+R + F++ DK+ +GYI E R Sbjct: 348 --------KMNDTDSEEEIR--EAFRVFDKDGNGYIGAAELR 379 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 34/66 (51%) Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 E+ F VFDKD NG+I E V++ +E++ + D++ DG + ++E Sbjct: 355 EEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEF 414 Query: 122 LTIVAS 127 + ++ + Sbjct: 415 VQMMTA 420 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D +G F EF+T+++ T EE++ AF ++D + +GYI E+ ++ Sbjct: 324 MINEVDADGDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMT 383 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 +G +T DE EM ++ D + DG + +EF Sbjct: 384 D----LGEKLT---DEEVDEM-----IRVADIDGDGQVNYEEF 414 >3HZT-A nrPDB Length = 467 Score = 47.0 bits (110), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 24/141 (17%) Query: 41 GQLAREDFVKIYKQFFPF----------GSPEDFANHLFTVFDKDNNGFIHFEEFITVLS 90 GQL R++ ++ Y++ + E +H+ D D NG+I + EF+TV Sbjct: 329 GQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCM 388 Query: 91 TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVK 150 E+L AF+ +D + G IT +E+ + VT +DE + Sbjct: 389 DKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFG---------VTEVDDETWHQ---- 435 Query: 151 KIFKLMDKNEDGYITLDEFRE 171 + + DKN DG + +EF E Sbjct: 436 -VLQECDKNNDGEVDFEEFVE 455 Score = 27.7 bits (60), Expect = 3.0, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 20/92 (21%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQL--AREDFVKIYKQFFPFGSPEDFANHLFTVF--- 72 QS FDR ++ + F+ C QL +RE + ++QF GS + L +F Sbjct: 368 QSVDFDRNGYIEYSE-FVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFGVT 426 Query: 73 --------------DKDNNGFIHFEEFITVLS 90 DK+N+G + FEEF+ ++ Sbjct: 427 EVDDETWHQVLQECDKNNDGEVDFEEFVEMMQ 458 >5UKG-A nrPDB Length = 419 Score = 47.0 bits (110), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + DG F E LT++A Sbjct: 287 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFLTMMA-- 344 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + M VT E +++ F++ DK+ +GYI E R Sbjct: 345 -RKMSYRVT--------EEEIREAFRVFDKDGNGYIGAAELR 377 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 18/81 (22%), Positives = 40/81 (49%) Query: 47 DFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFE 106 +F+ + + + E+ F VFDKD NG+I E V++ +E++ Sbjct: 338 EFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIR 397 Query: 107 LYDLNHDGYITFDEMLTIVAS 127 + D++ DG + ++E + ++ + Sbjct: 398 VADIDGDGQVNYEEFVQMMTA 418 Score = 35.4 bits (80), Expect = 0.014, Method: Compositional matrix adjust. Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 13/98 (13%) Query: 73 DKDNNGFIHFEEFITVLS-TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 D D +G F EF+T+++ S EE++ AF ++D + +GYI E+ ++ Sbjct: 327 DADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTD---- 382 Query: 132 MGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 +G +T DE EM ++ D + DG + +EF Sbjct: 383 LGEKLT---DEEVDEM-----IRVADIDGDGQVNYEEF 412 >3KHE-A nrPDB Length = 191 Score = 47.0 bits (110), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 24/141 (17%) Query: 41 GQLAREDFVKIYKQFFPF----------GSPEDFANHLFTVFDKDNNGFIHFEEFITVLS 90 GQL R++ ++ Y++ + E +H+ D D NG+I + EF+TV Sbjct: 55 GQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCM 114 Query: 91 TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVK 150 E+L AF+ +D + G IT +E+ + VT +DE + Sbjct: 115 DKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFG---------VTEVDDETWHQ---- 161 Query: 151 KIFKLMDKNEDGYITLDEFRE 171 + + DKN DG + +EF E Sbjct: 162 -VLQECDKNNDGEVDFEEFVE 181 Score = 28.5 bits (62), Expect = 1.8, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 20/92 (21%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQL--AREDFVKIYKQFFPFGSPEDFANHLFTVF--- 72 QS FDR ++ + F+ C QL +RE + ++QF GS + L +F Sbjct: 94 QSVDFDRNGYIEYSE-FVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFGVT 152 Query: 73 --------------DKDNNGFIHFEEFITVLS 90 DK+N+G + FEEF+ ++ Sbjct: 153 EVDDETWHQVLQECDKNNDGEVDFEEFVEMMQ 184 >5A2H-A nrPDB Length = 149 Score = 46.6 bits (109), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + +G I F E L ++A Sbjct: 17 FSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARK 76 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +K+ F++ DK+++G+I+ E R Sbjct: 77 MK-----------DTDSEEELKEAFRVFDKDQNGFISAAELR 107 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 52/103 (50%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NG I F EF+ +++ + T EE+L AF ++D + +G+I+ E+ ++ Sbjct: 52 MINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMT 111 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + +G +T DE EM + D + DG I +EF Sbjct: 112 N----LGEKLT---DEEVDEM-----IREADVDGDGQINYEEF 142 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 31/59 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F VFDKD NGFI E V++ +E++ D++ DG I ++E + ++ + Sbjct: 90 FRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMMA 148 >2LM5-A nrPDB Length = 214 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 46/183 (25%), Positives = 80/183 (43%), Gaps = 22/183 (12%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQF----- 55 MG S+LSK+ L + T+ ++EI H+ F P Q + E ++ F Sbjct: 24 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 83 Query: 56 FPFGSPEDFANHLFTVFD----KDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLN 111 P F + VF KD+ F F + ++V S T T + K +AF ++D + Sbjct: 84 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDT--ATPDIKSHYAFRIFDFD 141 Query: 112 HDGYITFDEMLTIVASVYKMMGSMVTLNEDE--ATPEMR--VKKIFKLMDKNEDGYITLD 167 DG + +++ +++ + ED + EM+ + I + D + DG I L Sbjct: 142 DDGTLNREDL-------SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 194 Query: 168 EFR 170 EF+ Sbjct: 195 EFQ 197 >3K21-A nrPDB Length = 191 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 10/109 (9%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSW-AFELYDLNHDGYITFDEMLTIVA 126 L D D +G I + EFI + R L +KL + AF ++D+++DG IT E+ I+ Sbjct: 92 LLDQIDSDGSGKIDYTEFIA--AALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILY 149 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 + K G++ + + RVK++ + +DKN DG I EF E K+ Sbjct: 150 NGNKK-GNITQRDVN------RVKRMIRDVDKNNDGKIDFHEFSEMMKL 191 >3QRX-A nrPDB Length = 169 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 35/123 (28%), Positives = 61/123 (49%), Gaps = 15/123 (12%) Query: 49 VKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTT--SRGTLEEKLSWAFE 106 +K+ + F ++ + + DKD +G I FEEF+T+++ R + EE L AF Sbjct: 50 LKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILK-AFR 108 Query: 107 LYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITL 166 L+D ++ G IT ++ V K +G +T E ++++ D+N+D I Sbjct: 109 LFDDDNSGTITIKDL----RRVAKELGENLTEEE--------LQEMIAEADRNDDNEIDE 156 Query: 167 DEF 169 DEF Sbjct: 157 DEF 159 Score = 31.6 bits (70), Expect = 0.20, Method: Compositional matrix adjust. Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 11/108 (10%) Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 F +FD D +G I +E + +E++ D + G I F+E LT++ Sbjct: 32 EAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMT 91 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 + MG + E + K F+L D + G IT+ + R +K Sbjct: 92 A---KMGERDSREE--------ILKAFRLFDDDNSGTITIKDLRRVAK 128 Score = 30.4 bits (67), Expect = 0.50, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 25/57 (43%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F +FD DN+G I ++ V EE+L D N D I DE + I+ Sbjct: 107 FRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIM 163 >5I0I-E nrPDB Length = 145 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++ DKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 15 FSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 74 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K + E +++ F++ DK+ +GYI+ E R Sbjct: 75 MK-----------DTDSEEEIREAFRVFDKDGNGYISAAELR 105 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NG I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 50 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 109 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + +G +T E V ++ + D + DG + +EF Sbjct: 110 N----LGEKLTDEE--------VDEMIREADIDGDGQVNYEEF 140 Score = 35.4 bits (80), Expect = 0.016, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 30/57 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F VFDKD NG+I E V++ +E++ D++ DG + ++E + ++ Sbjct: 88 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 144 >3L19-A nrPDB Length = 214 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 37/134 (27%), Positives = 60/134 (44%), Gaps = 14/134 (10%) Query: 41 GQLAREDFVKIYKQF-------FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTS 93 GQL R++ + Y + F E + + D D NG+I + EF+TV Sbjct: 78 GQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRK 137 Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIV------ASVYKMMGSMVTLNED-EATPE 146 ++KL AF+ +D + +G I+ DE+ ++ + +K M S + N D + E Sbjct: 138 SLLSKDKLESAFQKFDQDGNGKISVDELASVFGLDHLESKTWKEMISGIDSNNDGDVDFE 197 Query: 147 MRVKKIFKLMDKNE 160 K I KL NE Sbjct: 198 EFCKMIQKLCSNNE 211 >2E30-A nrPDB Length = 195 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 53/193 (27%), Positives = 83/193 (43%), Gaps = 41/193 (21%) Query: 1 MGAKTSKLSKDD-LTCLKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKI------ 51 MG++ S L +D+ L +K+ T F +I + + F L +G L+REDF +I Sbjct: 1 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAIN 60 Query: 52 ------YKQFFPFGSPEDFAN---------HLFTVFDKDNNGFIHFEEFITVLSTTSRGT 96 FFP G ED N H + D + + ++ E + S Sbjct: 61 PLGDRIINAFFPEG--EDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSN----- 113 Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 KL +AF LYDL+ D I+ DE+L V +M MV +N + + + Sbjct: 114 ---KLHFAFRLYDLDKDEKISRDELL----QVLRM---MVGVNISDEQLGSIADRTIQEA 163 Query: 157 DKNEDGYITLDEF 169 D++ D I+ EF Sbjct: 164 DQDGDSAISFTEF 176 >2M97-A nrPDB Length = 69 Score = 44.3 bits (103), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 34/63 (53%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 + F +FDKD NGFI EEF ++ T +E + F D + +G I FDE L ++ Sbjct: 6 SECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFLKMM 65 Query: 126 ASV 128 +V Sbjct: 66 ENV 68 >1LKJ-A nrPDB Length = 146 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FDKDNNG I E TV+ + E +++ D++ + I F E L +++ Sbjct: 16 FALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQ 75 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K S E + + FK+ DKN DG I+ E + Sbjct: 76 LKSNDS-----------EQELLEAFKVFDKNGDGLISAAELK 106 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 2/90 (2%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT-LE 98 +G ++ + + + E N L D D N I F EF+ ++S + E Sbjct: 24 NGSISSSELATVMRSL-GLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSE 82 Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASV 128 ++L AF+++D N DG I+ E+ ++ S+ Sbjct: 83 QELLEAFKVFDKNGDGLISAAELKHVLTSI 112 >3LIJ-A nrPDB Length = 494 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 37/134 (27%), Positives = 60/134 (44%), Gaps = 14/134 (10%) Query: 41 GQLAREDFVKIYKQF-------FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTS 93 GQL R++ + Y + F E + + D D NG+I + EF+TV Sbjct: 361 GQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRK 420 Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIV------ASVYKMMGSMVTLNED-EATPE 146 ++KL AF+ +D + +G I+ DE+ ++ + +K M S + N D + E Sbjct: 421 SLLSKDKLESAFQKFDQDGNGKISVDELASVFGLDHLESKTWKEMISGIDSNNDGDVDFE 480 Query: 147 MRVKKIFKLMDKNE 160 K I KL NE Sbjct: 481 EFCKMIQKLCSNNE 494 >4RGJ-A nrPDB Length = 520 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 24/141 (17%) Query: 41 GQLAREDFVKIYKQFFPF----------GSPEDFANHLFTVFDKDNNGFIHFEEFITVLS 90 GQL R + + YK+ + E + + D D NG+I + EF+TV Sbjct: 386 GQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSIDLDQNGYIEYSEFLTVSI 445 Query: 91 TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVK 150 E+L AF+L+D + G I+ +E+ A ++ + + + E K Sbjct: 446 DRKLLLSTERLEKAFKLFDKDGSGKISANEL----AQLFGL---------SDVSSECW-K 491 Query: 151 KIFKLMDKNEDGYITLDEFRE 171 + K +D+N DG I EFR+ Sbjct: 492 TVLKEVDQNNDGEIDFKEFRD 512 >2LHI-A nrPDB Length = 176 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FDKDNNG I E TV+ + E +++ D++ + I F E L +++ Sbjct: 17 FALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQ 76 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K S E + + FK+ DKN DG I+ E + Sbjct: 77 LKSNDS-----------EQELLEAFKVFDKNGDGLISAAELK 107 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 2/90 (2%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT-LE 98 +G ++ + + + E N L D D N I F EF+ ++S + E Sbjct: 25 NGSISSSELATVMRSL-GLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSE 83 Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASV 128 ++L AF+++D N DG I+ E+ ++ S+ Sbjct: 84 QELLEAFKVFDKNGDGLISAAELKHVLTSI 113 >2LHH-A nrPDB Length = 128 Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FDKDNNG I E TV+ + E +++ D++ + I F E L +++ Sbjct: 16 FALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQ 75 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K S E + + FK+ DKN DG I+ E + Sbjct: 76 LKSNDS-----------EQELLEAFKVFDKNGDGLISAAELK 106 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 2/90 (2%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT-LE 98 +G ++ + + + E N L D D N I F EF+ ++S + E Sbjct: 24 NGSISSSELATVMRSL-GLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSE 82 Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASV 128 ++L AF+++D N DG I+ E+ ++ S+ Sbjct: 83 QELLEAFKVFDKNGDGLISAAELKHVLTSI 112 >4JWQ-A nrPDB Length = 199 Score = 43.5 bits (101), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 11/116 (9%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSW-AFELYDLNHDGYITFD 119 P++F + L D D +G I + EF+ + R L +KL + AF ++D+++DG IT Sbjct: 92 PQNF-DVLLDQIDSDGSGRIDYTEFLA--AALDRKHLSKKLIYCAFRVFDVDNDGEITTA 148 Query: 120 EMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E+ I+ + K GS+ + ++ VKK+ + +DKN DG I EF E K+ Sbjct: 149 ELAHILYNGNKK-GSITQKDVNQ------VKKMIQEVDKNNDGKIDFYEFCEMMKL 197 >4YZB-A nrPDB Length = 491 Score = 43.5 bits (101), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 18/107 (16%) Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTL--EEKLSWAFELYDLNHDGYITFDEMLTI 124 + D D NGFI + EF+TV R TL ++L AF ++D + G I+ E+ TI Sbjct: 390 QVLDAVDFDKNGFIEYSEFVTV--AMDRKTLLSRQRLERAFGMFDADGSGKISSSELATI 447 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 V+ + E +++ +D+N DG + +EFR+ Sbjct: 448 FG---------VSEVDSETW-----RRVLAEVDRNNDGEVDFEEFRQ 480 Score = 33.5 bits (75), Expect = 0.064, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 4/49 (8%) Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 + A+ MGS +T NE+ + + KIF+ MDKN DG + E EG Sbjct: 320 LAAAALLYMGSKLTTNEET----VELNKIFQRMDKNGDGQLDKQELMEG 364 Score = 30.0 bits (66), Expect = 0.57, Method: Compositional matrix adjust. Identities = 22/79 (27%), Positives = 42/79 (53%), Gaps = 3/79 (3%) Query: 91 TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVK 150 TT+ T+E L+ F+ D N DG + E++ + K+ G V+ D++ E V+ Sbjct: 333 TTNEETVE--LNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSAL-DQSAIEFEVE 389 Query: 151 KIFKLMDKNEDGYITLDEF 169 ++ +D +++G+I EF Sbjct: 390 QVLDAVDFDKNGFIEYSEF 408 >2LC5-A nrPDB Length = 151 Score = 43.1 bits (100), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FDKDN+ + EE TV+ ++K+S + YD ++ G + LTI+ Sbjct: 20 FQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKDNSGKFDQETFLTIMLE- 78 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 G V ED +KK F++ DK ++GYI+ E + Sbjct: 79 ---YGQEVDSTED-------IKKAFEIFDKEKNGYISASELK 110 Score = 33.9 bits (76), Expect = 0.039, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 16/100 (16%) Query: 72 FDKDNNGFIHFEEFITV-LSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYK 130 +DKDN+G E F+T+ L E + AFE++D +GYI+ E+ ++ + Sbjct: 59 YDKDNSGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTT--- 115 Query: 131 MMGSMVTLNE-DEATPEMRVKKIFKLMDKNEDGYITLDEF 169 +G +T E D+ E+ V E+G I +D+F Sbjct: 116 -LGEKLTEQEVDDLLKEIGV----------EEGLINVDDF 144 Score = 32.7 bits (73), Expect = 0.091, Method: Compositional matrix adjust. Identities = 27/105 (25%), Positives = 52/105 (49%), Gaps = 4/105 (3%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQF-FPFGSPEDFANHLFTVFDKDNNGFIHF 82 +++I + K + +D SG+ +E F+ I ++ S ED F +FDK+ NG+I Sbjct: 49 KQKISEIVKDYDKD-NSGKFDQETFLTIMLEYGQEVDSTEDI-KKAFEIFDKEKNGYISA 106 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 E VL+T E+++ + + +G I D+ + ++ S Sbjct: 107 SELKHVLTTLGEKLTEQEVDDLLKEIGV-EEGLINVDDFVKLITS 150 >1GGZ-A nrPDB Length = 148 Score = 43.1 bits (100), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I E TV+ + + E +L D + +G + F E L ++A Sbjct: 16 FSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFLGMMARK 75 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K T NE+E +++ F++ DK+ +G+++ E R Sbjct: 76 MK-----DTDNEEE------IREAFRVFDKDGNGFVSAAELR 106 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 24/103 (23%), Positives = 52/103 (50%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + + D+D NG + F EF+ +++ + T EE++ AF ++D + +G+++ E+ ++ Sbjct: 51 MMSEIDRDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMT 110 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + + + DE EM + D + DG + +EF Sbjct: 111 RLGEKLS-------DEEVDEM-----IRAADTDGDGQVNYEEF 141 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 32/66 (48%) Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 E+ F VFDKD NGF+ E V++ +E++ D + DG + ++E Sbjct: 82 EEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEF 141 Query: 122 LTIVAS 127 + ++ S Sbjct: 142 VRVLVS 147 >1OZS-A nrPDB Length = 73 Score = 42.7 bits (99), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 36/70 (51%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 G E+ + LF +FDK+ +G+I EE +L T E+ + + D N+DG I + Sbjct: 3 GKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDY 62 Query: 119 DEMLTIVASV 128 DE L + V Sbjct: 63 DEFLEFMKGV 72 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 12/78 (15%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 +G EE+LS F ++D N DGYI +E+ ++ + + T+ ED+ ++++ Sbjct: 2 KGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGE------TITEDD------IEELM 49 Query: 154 KLMDKNEDGYITLDEFRE 171 K DKN DG I DEF E Sbjct: 50 KDGDKNNDGRIDYDEFLE 67 >3Q5I-A nrPDB Length = 504 Score = 42.7 bits (99), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 39/160 (24%), Positives = 68/160 (42%), Gaps = 22/160 (13%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP-------EDFANHLF 69 K +T +R+E+ K ++ GQL +++ ++ Y F + E+ +++ Sbjct: 347 KLTTLEERKELTDIFKKLDKN-GDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNIL 405 Query: 70 TVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 D D NG+I + EFI+V EE+L AF L+D + G IT +E+ + Sbjct: 406 KEVDFDKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLFGLT- 464 Query: 130 KMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + E + D+N+D I DEF Sbjct: 465 -------------SISEKTWNDVLGEADQNKDNMIDFDEF 491 >2KSZ-A nrPDB Length = 76 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 33/58 (56%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 F +FDKD +G I EE TV+ + + EE+L D + +G I FDE L+++A Sbjct: 16 FGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLMA 73 Score = 30.4 bits (67), Expect = 0.42, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 12/66 (18%) Query: 104 AFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGY 163 AF L+D + DG IT +E+ T++ S+ D+ E ++ + +D + +G Sbjct: 15 AFGLFDKDGDGCITVEELATVIRSL------------DQNPTEEELQDMISEVDADGNGT 62 Query: 164 ITLDEF 169 I DEF Sbjct: 63 IEFDEF 68 >4DS7-A nrPDB Length = 147 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FDKDN+G I E TV+ + E +++ D++ + I F E L +++ Sbjct: 17 FALFDKDNSGSISASELATVMRSLGLSPSEAEVADLMNEIDVDGNHAIEFSEFLALMSRQ 76 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K S E + + FK+ DKN DG I+ E + Sbjct: 77 LKCNDS-----------EQELLEAFKVFDKNGDGLISAAELK 107 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR-GTLE 98 SG ++ + + + S + A+ L D D N I F EF+ ++S + E Sbjct: 25 SGSISASELATVMRSLGLSPSEAEVAD-LMNEIDVDGNHAIEFSEFLALMSRQLKCNDSE 83 Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASV 128 ++L AF+++D N DG I+ E+ ++ S+ Sbjct: 84 QELLEAFKVFDKNGDGLISAAELKHVLTSI 113 >2BEC-A nrPDB Length = 202 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 46/156 (29%), Positives = 67/156 (42%), Gaps = 30/156 (19%) Query: 21 YFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPE-DFAN------HLFTVFD 73 Y R ++QQ G L P G +I + FFP GS DF H V D Sbjct: 45 YLSRMDLQQI--GALAVNPLGD-------RIIESFFPDGSQRVDFPGFVRVLAHFRPVED 95 Query: 74 KDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMG 133 +D E + KL +AF+LYDL+ DG I+ EML + + M+G Sbjct: 96 EDT-------ETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV---LRLMVG 145 Query: 134 SMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 VT + E + V++ D++ DG ++ EF Sbjct: 146 VQVTEEQLENIADRTVQE----ADEDGDGAVSFVEF 177 >5ZGM-A nrPDB Length = 110 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 7/84 (8%) Query: 52 YKQFFPF----GSPEDFANHLFTVFDKDNNGFIHFEEFITVL---STTSRGTLEEKLSWA 104 YK+FF G E +F + DKD +GFI EE +VL S R + + Sbjct: 27 YKRFFQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTETKAL 86 Query: 105 FELYDLNHDGYITFDEMLTIVASV 128 D +HDG I DE +VA Sbjct: 87 LAAGDSDHDGKIGADEFAKMVAQA 110 Score = 27.3 bits (59), Expect = 4.4, Method: Compositional matrix adjust. Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 3/42 (7%) Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 YK +V L + E +VK++F+++DK++ G+I +E + Sbjct: 27 YKRFFQLVGL---KGKSEAQVKEVFEILDKDQSGFIEEEELK 65 >3O4Y-A nrPDB Length = 196 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 36/116 (31%), Positives = 62/116 (53%), Gaps = 11/116 (9%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSW-AFELYDLNHDGYITFD 119 P +F + L D D +G I + EF+ + R L +KL + AF ++D+++DG IT Sbjct: 89 PPNF-DLLLDQIDSDGSGNIDYTEFLA--AAIDRRQLSKKLIYCAFRVFDVDNDGEITTA 145 Query: 120 EMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E+ ++ + K G++ + ++ VKK+ + +DKN DG I EF E K+ Sbjct: 146 ELAHVLFNGNKR-GNITERDVNQ------VKKMIREVDKNGDGKIDFYEFSEMMKL 194 >3NCG-A nrPDB Length = 486 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 29/146 (19%) Query: 41 GQLAREDFVKIYKQFFPF-------------GSPEDFANHLFTVFDKDNNGFIHFEEFIT 87 G L R++ V+ Y +F + ED + L + D D +G I + EFI Sbjct: 346 GMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLLDMDGSGSIEYSEFIA 405 Query: 88 VLSTTSRGTL--EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATP 145 S R L E++ AF+++D + G I+ E+ + + S + + E E+ Sbjct: 406 --SAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKL----FSQADSSIQMEELES-- 457 Query: 146 EMRVKKIFKLMDKNEDGYITLDEFRE 171 I + +D N+DG + +EF E Sbjct: 458 ------IIEQVDNNKDGEVDFNEFVE 477 Score = 32.7 bits (73), Expect = 0.089, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 29/59 (49%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F +FDKD +G I +E + S E+L E D N DG + F+E + ++ + Sbjct: 423 FKMFDKDGSGKISTKELFKLFSQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQN 481 Score = 27.3 bits (59), Expect = 4.1, Method: Compositional matrix adjust. Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Query: 96 TLEE--KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMG--SMVTLNEDEATPEMRVKK 151 TL+E +L+ F D N+DG + DE++ ++ G S + + +T E ++ Sbjct: 326 TLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDS 385 Query: 152 IFKLMDKNEDGYITLDEFREGSKVDPSII 180 + L+D + G I EF S +D +I+ Sbjct: 386 LMPLLDMDGSGSIEYSEFI-ASAIDRTIL 413 >1CLM-A nrPDB Length = 148 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FDKD +G I +E TV+ + + E +L D + +G I F E L+++A Sbjct: 16 FALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLSLMARK 75 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 K E E + + FK+ D++ +G I+ E R Sbjct: 76 MK-----------EQDSEEELIEAFKVFDRDGNGLISAAELR 106 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NG I F EF+++++ + EE+L AF+++D + +G I+ E+ ++ Sbjct: 51 MINEVDADGNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMT 110 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + +G +T +E V ++ + D + DG+I +EF Sbjct: 111 N----LGEKLTDDE--------VDEMIREADIDGDGHINYEEF 141 Score = 35.4 bits (80), Expect = 0.016, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 31/59 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F VFD+D NG I E V++ ++++ D++ DG+I ++E + ++ S Sbjct: 89 FKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMMVS 147 >1YX7-A nrPDB Length = 83 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 14/73 (19%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVK----KIFKLM 156 L AF+ D N DGY+T E+ T MVTL+ +A + +VK K+ K+ Sbjct: 9 LEAAFKKLDANGDGYVTALELQTF----------MVTLDAYKALSKDKVKEASAKLIKMA 58 Query: 157 DKNEDGYITLDEF 169 DKN DG I+ +EF Sbjct: 59 DKNSDGKISKEEF 71 >5E37-A nrPDB Length = 356 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 20/110 (18%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTL---------EEKLSWAFELYDLNHDGYITFD 119 F + D D NG I EE +L + G + E++L E YD+N DG I+F+ Sbjct: 35 FKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVNKDGVISFE 94 Query: 120 EMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 E I+ + G TL E E+ FK +DK+ +G I E Sbjct: 95 EFKQIIYDGLLLEG---TLAEYESA--------FKAVDKSGNGTIGATEL 133 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 15/111 (13%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVL--STTSRGTLEEKLSWAFELYDLNHDGYITF 118 PED +D + +G I FEEF ++ GTL E S AF+ D + +G I Sbjct: 72 PEDELERCMEQYDVNKDGVISFEEFKQIIYDGLLLEGTLAEYES-AFKAVDKSGNGTIGA 130 Query: 119 DEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 E+ + AS +G+ V+L ++ + ++ DK++ G I EF Sbjct: 131 TELSKLFAS----LGNPVSLE--------KLVDLMQMYDKDDSGQIEFPEF 169 Score = 28.9 bits (63), Expect = 1.4, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 24/56 (42%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 F DK NG I E + ++ EKL ++YD + G I F E L + Sbjct: 117 FKAVDKSGNGTIGATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEFPEFLLM 172 >2LV7-A nrPDB Length = 100 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Query: 57 PFGSPEDFANHL---FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHD 113 P PED + F VFD+D NGFI +E T + + E +L + D++ D Sbjct: 27 PVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGD 86 Query: 114 GYITFDEMLTIVAS 127 G + F+E +T++ Sbjct: 87 GQVDFEEFVTLLGP 100 Score = 26.6 bits (57), Expect = 6.2, Method: Compositional matrix adjust. Identities = 18/71 (25%), Positives = 38/71 (53%), Gaps = 12/71 (16%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 E++ AF+++D + +G+I+ E+ T + S +G M E+ ++ I + +D Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRS----LGYMPN--------EVELEVIIQRLDM 83 Query: 159 NEDGYITLDEF 169 + DG + +EF Sbjct: 84 DGDGQVDFEEF 94 >2AAO-A nrPDB Length = 166 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 14/102 (13%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 L D DN+G I ++EFI ++ E+ L AF +D + GYIT DE+ Sbjct: 68 LMQAADVDNSGTIDYKEFIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQAC-- 125 Query: 128 VYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 E+ ++R++++ + +D++ DG I +EF Sbjct: 126 ------------EEFGVEDVRIEELMRDVDQDNDGRIDYNEF 155 Score = 33.5 bits (75), Expect = 0.057, Method: Compositional matrix adjust. Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 14/115 (12%) Query: 60 SPEDFAN--HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYIT 117 S E+ A +F + D D +G I FEE L E ++ + D+++ G I Sbjct: 22 SEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTID 81 Query: 118 FDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 + E + TL+ ++ E + F DK+ GYIT DE ++ Sbjct: 82 YKEFIA------------ATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQA 124 >1S6I-A nrPDB Length = 188 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 12/108 (11%) Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 LF + D DN+G I F+E L +E ++ + D++ G I + E I A Sbjct: 14 ELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEF--IAA 71 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 +V+ LN+ E E + F DK+ GYITLDE ++ K Sbjct: 72 TVH--------LNKLE--REENLVSAFSYFDKDGSGYITLDEIQQACK 109 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 14/102 (13%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 L D D +G I + EFI ++ EE L AF +D + GYIT DE+ Sbjct: 51 LMDAADIDKSGTIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQAC-- 108 Query: 128 VYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 +D ++ + + K +D++ DG I EF Sbjct: 109 ------------KDFGLDDIHIDDMIKEIDQDNDGQIDYGEF 138 Score = 27.3 bits (59), Expect = 4.1, Method: Compositional matrix adjust. Identities = 11/26 (42%), Positives = 19/26 (73%) Query: 149 VKKIFKLMDKNEDGYITLDEFREGSK 174 +K++FK++D + G IT DE ++G K Sbjct: 12 LKELFKMIDTDNSGTITFDELKDGLK 37 >5MWC-D nrPDB Length = 311 Score = 39.7 bits (91), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 34/67 (50%) Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 E+ + F FDKD +GFI EEF ++ T +E F D + +G I FDE Sbjct: 150 EEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEF 209 Query: 122 LTIVASV 128 L +V +V Sbjct: 210 LKMVENV 216 Score = 28.5 bits (62), Expect = 1.8, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 12/84 (14%) Query: 86 ITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATP 145 + S T+ EE+LS F +D + DG+I +E I+ ++ G +T DE Sbjct: 138 VMANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGII----RLTGEQLT---DEDPD 190 Query: 146 EMRVKKIFKLMDKNEDGYITLDEF 169 E IF D +++G I DEF Sbjct: 191 E-----IFGDSDTDKNGRIDFDEF 209 >2LMV-A nrPDB Length = 148 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 11/102 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F FDK+ G I E T++ T + E +L + N++G + F E I+A Sbjct: 16 FVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNGQLNFTEFCGIMAKQ 75 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + E E +++ FK+ D++ DG+I+ E R Sbjct: 76 MR-----------ETDTEEEMREAFKIFDRDGDGFISPAELR 106 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 31/103 (30%), Positives = 54/103 (52%), Gaps = 13/103 (12%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 L + +NNG ++F EF +++ R T EE++ AF+++D + DG+I+ E+ ++ Sbjct: 51 LIAEAENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMI 110 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + +G VT DE EM + D + DG I +EF Sbjct: 111 N----LGEKVT---DEEIDEM-----IREADFDGDGMINYEEF 141 Score = 34.3 bits (77), Expect = 0.029, Method: Compositional matrix adjust. Identities = 21/88 (23%), Positives = 39/88 (44%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 +GQL +F I + E+ F +FD+D +GFI E V+ +E Sbjct: 60 NGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEKVTDE 119 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVAS 127 ++ D + DG I ++E + +++ Sbjct: 120 EIDEMIREADFDGDGMINYEEFVWMISQ 147 >2M29-A nrPDB Length = 171 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 26/114 (22%), Positives = 54/114 (47%), Gaps = 12/114 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA-S 127 F FD D +G+I + E + T E +L + + G++ F+E + +++ Sbjct: 34 FEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELISPK 93 Query: 128 VYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIG 181 + + M+ + E ++ F+ DK+ DG IT+ E R+ + P+++G Sbjct: 94 LREETAHMLGVRE--------LRIAFREFDKDRDGRITVAELRQAA---PALLG 136 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 1/60 (1%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLE-EKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F FDKD +G I E LE +L DLN DG I FDE + ++++ Sbjct: 111 FREFDKDRDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTIDFDEFVMMLST 170 >2HF5-A nrPDB Length = 68 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 37/62 (59%), Gaps = 1/62 (1%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NG I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 6 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 65 Query: 127 SV 128 ++ Sbjct: 66 NL 67 Score = 29.6 bits (65), Expect = 0.75, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 11/62 (17%) Query: 109 DLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE 168 D + +G I F E LT++A K + E +++ F++ DK+ +GYI+ E Sbjct: 11 DADGNGTIDFPEFLTMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAE 59 Query: 169 FR 170 R Sbjct: 60 LR 61 >2ROB-A nrPDB Length = 70 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 32/60 (53%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F VFDKD NG+I E V+ +E++ + DL+ DG + ++E + ++ +V Sbjct: 10 FKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTV 69 Score = 30.0 bits (66), Expect = 0.64, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 12/72 (16%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 EE+L AF+++D + +GYI+ E+ V +N E + V+++ K D Sbjct: 3 EEELKEAFKVFDKDQNGYISASEL------------RHVMINLGEKLTDEEVEQMIKEAD 50 Query: 158 KNEDGYITLDEF 169 + DG + +EF Sbjct: 51 LDGDGQVNYEEF 62 Score = 27.3 bits (59), Expect = 3.8, Method: Compositional matrix adjust. Identities = 11/26 (42%), Positives = 18/26 (69%) Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFR 170 E +K+ FK+ DK+++GYI+ E R Sbjct: 2 AEEELKEAFKVFDKDQNGYISASELR 27 >2RO9-A nrPDB Length = 69 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 31/59 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F VFDKD NGFI E V++ +E++ D++ DG I ++E + ++ + Sbjct: 10 FRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMMA 68 Score = 27.7 bits (60), Expect = 3.2, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 12/72 (16%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 EE+L AF ++D + +G+I+ E+ ++ + +G +T DE EM + D Sbjct: 3 EEELKEAFRVFDKDQNGFISAAELRHVMTN----LGEKLT---DEEVDEM-----IREAD 50 Query: 158 KNEDGYITLDEF 169 + DG I +EF Sbjct: 51 VDGDGQINYEEF 62 >5PAL-A nrPDB Length = 109 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 7/84 (8%) Query: 52 YKQFFPF----GSPEDFANHLFTVFDKDNNGFIHFEEFITVL---STTSRGTLEEKLSWA 104 YK+FF G + +F + DKD +GFI EE VL S R + + Sbjct: 26 YKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKAL 85 Query: 105 FELYDLNHDGYITFDEMLTIVASV 128 D +HDG I DE +VA Sbjct: 86 LAAGDSDHDGKIGADEFAKMVAQA 109 >3KF9-A nrPDB Length = 149 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 17/148 (11%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFE 83 ++EI++ F D A+E +K+ + F ++ + DKD +G I FE Sbjct: 7 KQEIREAFDLFDTDGSGTIDAKE--LKVAMRALGFEPKKEEIKKMIADIDKDGSGTIDFE 64 Query: 84 EFITVLSTT--SRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNED 141 EF+ +++ R + EE + AF L+D + G I+F + V K +G +T D Sbjct: 65 EFLQMMTAKMGERDSREE-IMKAFRLFDDDETGKISFKNL----KRVAKELGENMT---D 116 Query: 142 EATPEMRVKKIFKLMDKNEDGYITLDEF 169 E EM D++ DG + +EF Sbjct: 117 EELQEM-----IDEADRDGDGEVNEEEF 139 >2KN2-A nrPDB Length = 92 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 34/68 (50%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 E+ F VFDKD NG+I E V+ +E++ + DL+ DG + ++E Sbjct: 7 AEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEE 66 Query: 121 MLTIVASV 128 + ++ +V Sbjct: 67 FVKMMMTV 74 Score = 30.4 bits (67), Expect = 0.45, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 12/72 (16%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 EE+L AF+++D + +GYI+ E+ + M+ L E E V+++ K D Sbjct: 8 EEELKEAFKVFDKDQNGYISASELRHV----------MINLGEKLTDEE--VEQMIKEAD 55 Query: 158 KNEDGYITLDEF 169 + DG + +EF Sbjct: 56 LDGDGQVNYEEF 67 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 11/26 (42%), Positives = 18/26 (69%) Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFR 170 E +K+ FK+ DK+++GYI+ E R Sbjct: 7 AEEELKEAFKVFDKDQNGYISASELR 32 >5COC-A nrPDB Length = 130 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 33/62 (53%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 69 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 128 Query: 129 YK 130 K Sbjct: 129 MK 130 >3IFK-A nrPDB Length = 90 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 33/64 (51%) Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 14 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 73 Query: 127 SVYK 130 K Sbjct: 74 RKMK 77 >2JNX-A nrPDB Length = 134 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 37/129 (28%), Positives = 55/129 (42%), Gaps = 25/129 (19%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A LF D + +G + +EE +S+ E+ L F+ D++ +G I E Sbjct: 2 AEALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKF 61 Query: 125 VASV---------------YKMMGSMV--TLNEDEATP-------EMRVKKIFKLMDKNE 160 A+V YK+M + L ++E T E V +I K D N Sbjct: 62 AAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGYEKVVDQIMK-ADANG 120 Query: 161 DGYITLDEF 169 DGYITL+EF Sbjct: 121 DGYITLEEF 129 >2BL0-C nrPDB Length = 142 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 2/78 (2%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 +G + +E + KQF P F N +F D NG I F EF++++ + T E Sbjct: 20 TGFITKEGLQTVLKQFGVRVEPAAF-NEMFNEADATGNGKIQFPEFLSMMGRRMKQTTSE 78 Query: 100 K-LSWAFELYDLNHDGYI 116 L AF +D GYI Sbjct: 79 DILRQAFRTFDPEGTGYI 96 Score = 30.4 bits (67), Expect = 0.49, Method: Compositional matrix adjust. Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 11/96 (11%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FD + GFI E TVL + F D +G I F E L+ Sbjct: 12 FELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQFPEFLS----- 66 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYI 164 MMG + + T E +++ F+ D GYI Sbjct: 67 --MMGRRM----KQTTSEDILRQAFRTFDPEGTGYI 96 >2LAP-A nrPDB Length = 167 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 25/107 (23%), Positives = 48/107 (44%), Gaps = 9/107 (8%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA-S 127 F FDKD +G+I+ + + T E +L + ++N G++ FD+ + ++ Sbjct: 31 FREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPK 90 Query: 128 VYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 + M+ + E ++ F+ D N DG I+ E RE + Sbjct: 91 LLAETADMIGVKE--------LRDAFREFDTNGDGEISTSELREAMR 129 Score = 27.7 bits (60), Expect = 2.9, Method: Compositional matrix adjust. Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 17/95 (17%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 E+L AF +D + DGYI ++ + + MG M T EM + ++ + ++ Sbjct: 25 EELREAFREFDKDKDGYINCRDL----GNCMRTMGYMPT--------EMELIELSQQINM 72 Query: 159 NEDGYITLDEFRE--GSKV---DPSIIGALNLYDG 188 N G++ D+F E G K+ +IG L D Sbjct: 73 NLGGHVDFDDFVELMGPKLLAETADMIGVKELRDA 107 >3E3R-A nrPDB Length = 204 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 6/108 (5%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A + +D++ +G + EEF+ L E ++ AF D + DG +T D++ + Sbjct: 75 AEGVCRKWDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGV 134 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE-DGYITLDEFRE 171 + EDE +++ D +E DG +TL EF++ Sbjct: 135 YSGRAHPKVRSGEWTEDEV-----LRRFLDNFDSSEKDGQVTLAEFQD 177 >5H7D-E nrPDB Length = 120 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 20/58 (34%), Positives = 32/58 (55%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 62 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 119 >2RO8-A nrPDB Length = 79 Score = 36.6 bits (83), Expect = 0.008, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 32/62 (51%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FDKD +G I +E TV+ + + E +L D + +G I F E L ++A Sbjct: 16 FSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARK 75 Query: 129 YK 130 K Sbjct: 76 MK 77 >2OBH-A nrPDB Length = 143 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 31/122 (25%), Positives = 59/122 (48%), Gaps = 13/122 (10%) Query: 49 VKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTT-SRGTLEEKLSWAFEL 107 +K+ + F ++ + + DK+ G ++F +F+TV++ S +E++ AF+L Sbjct: 28 LKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKL 87 Query: 108 YDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLD 167 +D + G I+F + V K +G +T DE EM D++ DG ++ Sbjct: 88 FDDDETGKISFKNL----KRVAKELGENLT---DEELQEM-----IDEADRDGDGEVSEQ 135 Query: 168 EF 169 EF Sbjct: 136 EF 137 >2I08-A nrPDB Length = 78 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 33/62 (53%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F+++DKD +G I +E TV+ + E +L D + +G I F E LT++A + Sbjct: 16 FSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFPEFLTMMARI 75 Query: 129 YK 130 K Sbjct: 76 MK 77 >2GGM-A nrPDB Length = 172 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 31/122 (25%), Positives = 59/122 (48%), Gaps = 13/122 (10%) Query: 49 VKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTT-SRGTLEEKLSWAFEL 107 +K+ + F ++ + + DK+ G ++F +F+TV++ S +E++ AF+L Sbjct: 53 LKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKL 112 Query: 108 YDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLD 167 +D + G I+F + V K +G +T DE EM D++ DG ++ Sbjct: 113 FDDDETGKISFKNL----KRVAKELGENLT---DEELQEM-----IDEADRDGDGEVSEQ 160 Query: 168 EF 169 EF Sbjct: 161 EF 162 >4Q57-A nrPDB Length = 65 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 20/58 (34%), Positives = 32/58 (55%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++A Sbjct: 8 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 65 >3MSE-B nrPDB Length = 180 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 15/102 (14%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 + N LF D ++NG + E TVL++ G + ++ + D+N G IT+ E + Sbjct: 40 YINELFYKLDTNHNGSLSHREIYTVLASV--GIKKWDINRILQALDINDRGNITYTEFM- 96 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYIT 165 A Y+ T +K F +DK+EDGYI+ Sbjct: 97 --AGCYRWKNIESTF----------LKAAFNKIDKDEDGYIS 126 Score = 30.8 bits (68), Expect = 0.39, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 14/64 (21%) Query: 109 DLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE 168 D NH+G ++ E+ T++ASV + + +I + +D N+ G IT E Sbjct: 49 DTNHNGSLSHREIYTVLASV--------------GIKKWDINRILQALDINDRGNITYTE 94 Query: 169 FREG 172 F G Sbjct: 95 FMAG 98 >4BTS-A7 nrPDB Length = 162 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Query: 49 VKIYKQFFPFGS---PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAF 105 ++IYKQ G +DF H + G + +I V S RG LEE +W F Sbjct: 10 IRIYKQLLQDGVFVLKKDFEGH------HEETGVPNLHCYILVRSLKDRGFLEEIFNWGF 63 Query: 106 ELYDLNHDGYITFDEMLTIVA 126 Y LN +G L I A Sbjct: 64 TYYYLNKEGCEYLKTKLGISA 84 >1FW4-A nrPDB Length = 71 Score = 35.8 bits (81), Expect = 0.012, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 31/59 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F VFDKD NG+I E V++ +E++ D++ DG + ++E + ++ + Sbjct: 12 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 70 Score = 26.2 bits (56), Expect = 8.0, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 12/72 (16%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 EE++ AF ++D + +GYI+ E+ ++ + +G +T DE EM + D Sbjct: 5 EEEIREAFRVFDKDGNGYISAAELRHVMTN----LGEKLT---DEEVDEM-----IREAD 52 Query: 158 KNEDGYITLDEF 169 + DG + +EF Sbjct: 53 IDGDGQVNYEEF 64 >2M5E-A nrPDB Length = 73 Score = 35.4 bits (80), Expect = 0.014, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 31/59 (52%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F VFD+D NG I E V++ ++++ D++ DG+I ++E + ++ S Sbjct: 14 FKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMMVS 72 >1JFJ-A nrPDB Length = 134 Score = 34.7 bits (78), Expect = 0.023, Method: Compositional matrix adjust. Identities = 34/107 (31%), Positives = 46/107 (42%), Gaps = 19/107 (17%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEK---LSWAFELYDLNHDGYITFDEMLTI 124 +F D D NG I EF + L + L ++L D++ DG +T +E Sbjct: 41 IFKSIDADGNGEIDQNEFAKFYGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEE---- 96 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 V S +K G E E +K D N DGYITL+EF E Sbjct: 97 VTSFFKKHGI-------EKVAEQVMK-----ADANGDGYITLEEFLE 131 >6OKK-O nrPDB Length = 137 Score = 34.3 bits (77), Expect = 0.033, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 29/55 (52%) Query: 85 FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLN 139 +T+ S SR +EEK +W + + LN++G E L + S++ S T+N Sbjct: 54 MMTLKSLKSRNYVEEKYNWKHQYFILNNEGIEYLREFLHLPPSIFPATLSKKTVN 108 >1F55-A nrPDB Length = 77 Score = 33.9 bits (76), Expect = 0.038, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 31/62 (50%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FDKDNNG I E TV+ + E +++ D++ + I F E L +++ Sbjct: 16 FALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQ 75 Query: 129 YK 130 K Sbjct: 76 LK 77 >3I5H-B nrPDB Length = 153 Score = 33.9 bits (76), Expect = 0.039, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 33 GFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFI 80 L++CP GQL F+ ++ + PED + F++FD+D GFI Sbjct: 56 AMLKECP-GQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFI 102 Score = 30.4 bits (67), Expect = 0.49, Method: Compositional matrix adjust. Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 15/99 (15%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 FT+ D+D +GFI E+ + S+ R +++L+ + G + F LT+ Sbjct: 22 FTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAMLK----ECPGQLNFTAFLTLFGE- 76 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLD 167 K+ G+ PE ++ F + D++ G+I D Sbjct: 77 -KVSGT---------DPEDALRNAFSMFDEDGQGFIPED 105 >4NQG-A nrPDB Length = 197 Score = 33.9 bits (76), Expect = 0.045, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 8/62 (12%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTT----SRGTLEEKLSWAFELYDLNHDGYITFD 119 + + LF + DKD NG + +E+I SRG E F DL+ DG + D Sbjct: 115 WGDALFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEA----TFAHCDLDGDGKLDVD 170 Query: 120 EM 121 EM Sbjct: 171 EM 172 >5ZOR-A nrPDB Length = 149 Score = 33.9 bits (76), Expect = 0.045, Method: Compositional matrix adjust. Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 13/111 (11%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEF-ITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 P D + + NG I + EF V S ++ E++ AF+L+DL+ G I+F Sbjct: 42 PRDEVERTVRSMNTNANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISF- 100 Query: 120 EMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + V K++G E + ++++ D++ DG ++ +EF+ Sbjct: 101 ---ANLKEVAKLLG--------ENPGDDVLQEMIAEADEDGDGEVSFEEFK 140 >2B1U-A nrPDB Length = 71 Score = 33.5 bits (75), Expect = 0.061, Method: Compositional matrix adjust. Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 13/77 (16%) Query: 93 SRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKI 152 +R LE+ L AF +D + DG+IT DE+ +A + + + P+ + + Sbjct: 1 ARAGLED-LQVAFRAFDQDGDGHITVDELRRAMAGLGQPL------------PQEELDAM 47 Query: 153 FKLMDKNEDGYITLDEF 169 + D ++DG + +EF Sbjct: 48 IREADVDQDGRVNYEEF 64 >1NYA-A nrPDB Length = 176 Score = 33.5 bits (75), Expect = 0.061, Method: Compositional matrix adjust. Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 9/92 (9%) Query: 41 GQLAREDFVKIYKQFFPFGSPEDFANHLFTVF-------DKDNNGFIHFEEFITVLSTTS 93 G L E F+++ + F L V DK+ +G I+ +EF L T+ Sbjct: 73 GSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEFAAWL--TA 130 Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 G + + + AF D N +G ++ DE+LT V Sbjct: 131 LGMSKAEAAEAFNQVDTNGNGELSLDELLTAV 162 Score = 27.3 bits (59), Expect = 4.0, Method: Compositional matrix adjust. Identities = 12/21 (57%), Positives = 13/21 (61%) Query: 149 VKKIFKLMDKNEDGYITLDEF 169 VK I + DKN DG I DEF Sbjct: 104 VKGIVGMCDKNADGQINADEF 124 >4N5X-A nrPDB Length = 199 Score = 33.1 bits (74), Expect = 0.076, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 7/73 (9%) Query: 56 FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 P G +D +FT D + +G + FEEF+ L E+K+ AF+ D N+DG Sbjct: 53 IPLG--QDAEEKIFTTGDVNKDGKLDFEEFMKYLKDH-----EKKMKLAFKSLDKNNDGK 105 Query: 116 ITFDEMLTIVASV 128 I E++ + ++ Sbjct: 106 IEASEIVQSLQTL 118 Score = 29.3 bits (64), Expect = 1.0, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 23/105 (21%) Query: 68 LFTVFDKDNNGFI---HFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 LF D++ +G + +E + L EEK+ F D+N DG + F+E + Sbjct: 27 LFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKI---FTTGDVNKDGKLDFEEFMKY 83 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + K M K FK +DKN DG I E Sbjct: 84 LKDHEKKM-----------------KLAFKSLDKNNDGKIEASEI 111 Score = 26.6 bits (57), Expect = 6.7, Method: Compositional matrix adjust. Identities = 11/38 (28%), Positives = 21/38 (55%) Query: 135 MVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 + T +A R + +F+ +D+N DG + + E +EG Sbjct: 10 LPTAASQDAEQPTRYETLFQALDRNGDGVVDIGELQEG 47 >4ZCV-A nrPDB Length = 165 Score = 33.1 bits (74), Expect = 0.079, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 7/73 (9%) Query: 56 FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 P G +D +FT D + +G + FEEF+ L E+K+ AF+ D N+DG Sbjct: 44 IPLG--QDAEEKIFTTGDVNKDGKLDFEEFMKYLKDH-----EKKMKLAFKSLDKNNDGK 96 Query: 116 ITFDEMLTIVASV 128 I E++ + ++ Sbjct: 97 IEASEIVQSLQTL 109 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 27/105 (25%), Positives = 42/105 (40%), Gaps = 23/105 (21%) Query: 68 LFTVFDKDNNGFI---HFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 LF D++ +G + +E + L EEK+ F D+N DG + F+E + Sbjct: 18 LFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKI---FTTGDVNKDGKLDFEEFMKY 74 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + E ++K FK +DKN DG I E Sbjct: 75 LKD-----------------HEKKMKLAFKSLDKNNDGKIEASEI 102 Score = 26.6 bits (57), Expect = 7.8, Method: Compositional matrix adjust. Identities = 10/31 (32%), Positives = 19/31 (61%) Query: 142 EATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 +A R + +F+ +D+N DG + + E +EG Sbjct: 8 DAEQPTRYETLFQALDRNGDGVVDIGELQEG 38 >2JNF-A nrPDB Length = 158 Score = 33.1 bits (74), Expect = 0.082, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Query: 67 HLFTVFDKDNNGFIHFEEFITVLS-----TTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 L FD NG I F+ F + + + ++++L AF LYD +GYI+ D M Sbjct: 54 QLIDEFDPFGNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVM 113 Query: 122 LTIVASVYKMMGS 134 I+A + + + S Sbjct: 114 REILAELDETLSS 126 Score = 27.7 bits (60), Expect = 2.8, Method: Compositional matrix adjust. Identities = 16/71 (22%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Query: 60 SPEDFANHL---FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYI 116 +PE L F ++DK+ NG+I + +L+ E L + D + G + Sbjct: 85 NPEQMQQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTV 144 Query: 117 TFDEMLTIVAS 127 F+E + ++ Sbjct: 145 DFEEFMGVMTG 155 Score = 26.6 bits (57), Expect = 7.2, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 7/64 (10%) Query: 108 YDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLD 167 +D +G I FD I A + +G V N ++ E+R + F+L DK +GYI+ D Sbjct: 59 FDPFGNGDIDFDSFKIIGA---RFLGEEV--NPEQMQQELR--EAFRLYDKEGNGYISTD 111 Query: 168 EFRE 171 RE Sbjct: 112 VMRE 115 >1JF0-A nrPDB Length = 195 Score = 32.7 bits (73), Expect = 0.085, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 30/59 (50%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 ++ + +F +FDKD +G I +E+ + EE F+ DL++ G + DEM Sbjct: 113 EWGDAVFDIFDKDGSGTITLDEWKAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDEM 171 >5ZH6-A nrPDB Length = 107 Score = 32.7 bits (73), Expect = 0.10, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 3/61 (4%) Query: 68 LFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 +F + D+D +GFI +E F+ S T+R E + + D +HDG I DE + Sbjct: 45 VFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDSDHDGKIGVDEFKAM 104 Query: 125 V 125 V Sbjct: 105 V 105 >1TIZ-A nrPDB Length = 67 Score = 32.7 bits (73), Expect = 0.10, Method: Compositional matrix adjust. Identities = 13/23 (56%), Positives = 19/23 (82%) Query: 149 VKKIFKLMDKNEDGYITLDEFRE 171 K++F+ DKN+DG ++LDEFRE Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFRE 25 Score = 28.1 bits (61), Expect = 2.4, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 30/61 (49%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A +F FDK+ +G + +EF V S +E + FE D++ +G + DE + Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTSC 62 Query: 125 V 125 + Sbjct: 63 I 63 >2HPS-A nrPDB Length = 186 Score = 32.7 bits (73), Expect = 0.10, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 25/58 (43%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 ++ D D +G++ EF L ++K F D N +G I+ DE L V Sbjct: 107 MYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFLVTV 164 >2KZ2-A nrPDB Length = 94 Score = 32.3 bits (72), Expect = 0.12, Method: Compositional matrix adjust. Identities = 15/59 (25%), Positives = 30/59 (50%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F V DKD NG+I E V++ +E++ D++ DG + ++E + ++ + Sbjct: 35 FRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 93 >2OPO-A nrPDB Length = 86 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 13/76 (17%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYI 164 F+ +D N DG I+ E+ K +GS+ TP+ V+++ +D + DG+I Sbjct: 17 FKRFDTNGDGKISSSEL----GDALKTLGSV--------TPD-EVRRMMAEIDTDGDGFI 63 Query: 165 TLDEFREGSKVDPSII 180 + DEF + ++ + ++ Sbjct: 64 SFDEFTDFARANRGLV 79 >5VE9-A nrPDB Length = 91 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 1/88 (1%) Query: 39 PSGQLAREDFVKIYKQFFPF-GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTL 97 P G +A DF K++ + + F DKD +G I +EFI + + T Sbjct: 2 PGGHMANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTT 61 Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIV 125 + +++ +++D + DGYI + E + + Sbjct: 62 KLEMTAVADIFDRDGDGYIDYYEFVAAL 89 Score = 26.6 bits (57), Expect = 6.8, Method: Compositional matrix adjust. Identities = 12/25 (48%), Positives = 17/25 (68%) Query: 148 RVKKIFKLMDKNEDGYITLDEFREG 172 RV F+ +DK++DG IT EF +G Sbjct: 28 RVMDFFRRIDKDQDGKITRQEFIDG 52 >1TNP-A nrPDB Length = 90 Score = 32.0 bits (71), Expect = 0.16, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 29/62 (46%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FD D G I +E TV+ + +E+L E D + G I F+E L ++ Sbjct: 26 FDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQ 85 Query: 129 YK 130 K Sbjct: 86 MK 87 >3JAX-C nrPDB Length = 151 Score = 32.0 bits (71), Expect = 0.16, Method: Compositional matrix adjust. Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 12/86 (13%) Query: 52 YKQFFPF----------GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKL 101 ++QF P G ED+ L VFDK+ NG + E VL T EE++ Sbjct: 67 FEQFLPMMQTIAKNKDQGCFEDYVEGL-RVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEV 125 Query: 102 SWAFELYDLNHDGYITFDEMLTIVAS 127 ++ + +G I ++E++ +V S Sbjct: 126 EQLVAGHE-DSNGCINYEELVRMVLS 150 >1RTP-1 nrPDB Length = 109 Score = 32.0 bits (71), Expect = 0.18, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 7/82 (8%) Query: 52 YKQFFPF----GSPEDFANHLFTVFDKDNNGFIHFEEFITVL---STTSRGTLEEKLSWA 104 +K+FF D +F + DKD +GFI +E ++L S+ +R ++ Sbjct: 26 HKKFFQMVGLKKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTL 85 Query: 105 FELYDLNHDGYITFDEMLTIVA 126 D + DG I +E T+VA Sbjct: 86 MAAGDKDGDGKIGVEEFSTLVA 107 Score = 26.2 bits (56), Expect = 8.5, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 21/35 (60%), Gaps = 3/35 (8%) Query: 135 MVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 MV L + A VKK+F ++DK++ G+I DE Sbjct: 32 MVGLKKKSADD---VKKVFHILDKDKSGFIEEDEL 63 >1C7W-A nrPDB Length = 81 Score = 31.6 bits (70), Expect = 0.19, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 11/76 (14%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 R EE++ AF+++D N DG I FDE I+ V + E + V++ Sbjct: 3 RQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGE-----------EPLTDAEVEEAM 51 Query: 154 KLMDKNEDGYITLDEF 169 K D++ +G I + EF Sbjct: 52 KEADEDGNGVIDIPEF 67 Score = 26.9 bits (58), Expect = 5.8, Method: Compositional matrix adjust. Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTL-EEKLSWAFELYDLNHDGYITFDEMLTIV 125 F VFD + +G I F+EF ++ L + ++ A + D + +G I E + ++ Sbjct: 12 RAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEFMDLI 71 >1SL8-A nrPDB Length = 191 Score = 31.6 bits (70), Expect = 0.20, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 26/58 (44%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 + + LF + DKD NG I +E+ + E F + D++ G + DEM Sbjct: 110 WGDALFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEM 167 Score = 30.0 bits (66), Expect = 0.61, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 8/42 (19%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPE 146 F D+NH+G I+ DEM VYK S + +N ATPE Sbjct: 22 FNFLDVNHNGRISLDEM------VYK--ASDIVINNLGATPE 55 >1TRF-A nrPDB Length = 76 Score = 31.6 bits (70), Expect = 0.21, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 29/62 (46%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FD D G I +E TV+ + +E+L E D + G I F+E L ++ Sbjct: 15 FDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQ 74 Query: 129 YK 130 K Sbjct: 75 MK 76 >1G33-A nrPDB Length = 73 Score = 31.6 bits (70), Expect = 0.21, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 3/67 (4%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVL---STTSRGTLEEKLSWAFELYDLNHDGYITFD 119 D +F + DKD +GFI +E ++L S+ +R ++ D + DG I + Sbjct: 5 DDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVE 64 Query: 120 EMLTIVA 126 E T+VA Sbjct: 65 EFSTLVA 71 Score = 26.2 bits (56), Expect = 9.8, Method: Compositional matrix adjust. Identities = 10/21 (47%), Positives = 16/21 (76%) Query: 149 VKKIFKLMDKNEDGYITLDEF 169 VKK+F ++DK++ G+I DE Sbjct: 7 VKKVFHILDKDKSGFIEEDEL 27 >5XND-A nrPDB Length = 114 Score = 31.6 bits (70), Expect = 0.23, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 33/82 (40%), Gaps = 3/82 (3%) Query: 47 DFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSW 103 D K +K G D F + D+D +GFI EE F+ +R + + Sbjct: 31 DHKKFFKACGLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKA 90 Query: 104 AFELYDLNHDGYITFDEMLTIV 125 + D + DG I DE ++ Sbjct: 91 FLKAGDSDGDGKIGIDEFAAMI 112 >1BU3-A nrPDB Length = 109 Score = 31.2 bits (69), Expect = 0.25, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 7/81 (8%) Query: 52 YKQFFP----FGSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWA 104 YK FF D F V D+D +GFI +E F+ V S +R + + Sbjct: 27 YKAFFAKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAF 86 Query: 105 FELYDLNHDGYITFDEMLTIV 125 + D + DG I DE +V Sbjct: 87 LKAGDSDGDGAIGVDEWAALV 107 >1S36-A nrPDB Length = 195 Score = 31.2 bits (69), Expect = 0.26, Method: Compositional matrix adjust. Identities = 28/126 (22%), Positives = 52/126 (41%), Gaps = 13/126 (10%) Query: 9 SKDDLTCLKQSTYFDRREIQQWHKGFLRDCP---SGQLAREDFVKIYKQF-------FPF 58 + DD+ ++T + Q + F R C ++A F+ +KQ + Sbjct: 46 ASDDICAKLEATPEQTKRHQVCVEAFFRGCGMEYGKEIAFPQFLDGFKQLATSELKKWAR 105 Query: 59 GSP---EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 P ++ + +F +FDKD +G I +E+ + +E F DL++ G Sbjct: 106 NEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDLDNSGD 165 Query: 116 ITFDEM 121 + DEM Sbjct: 166 LDVDEM 171 >3J04-B nrPDB Length = 143 Score = 31.2 bits (69), Expect = 0.26, Method: Compositional matrix adjust. Identities = 20/97 (20%), Positives = 45/97 (46%), Gaps = 1/97 (1%) Query: 29 QWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITV 88 ++ +G + + P G + F+ ++ + PED + F FD++ +GFIH + + Sbjct: 43 EYLEGMMSEAP-GPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLREL 101 Query: 89 LSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 L+T +E++ + ++ G + E I+ Sbjct: 102 LTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRIL 138 >3FWC-A nrPDB Length = 161 Score = 31.2 bits (69), Expect = 0.26, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 28/66 (42%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 P D F +FD D+ G I + V +E+L E +DL+ DG I +E Sbjct: 94 PLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENE 153 Query: 121 MLTIVA 126 + I Sbjct: 154 FIAICT 159 Score = 28.5 bits (62), Expect = 2.0, Method: Compositional matrix adjust. Identities = 22/106 (20%), Positives = 46/106 (43%), Gaps = 11/106 (10%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F++FD +N+GF+ + E + + ++ + YD + +D+ Sbjct: 29 FSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDF------- 81 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 Y +MG + + P +K+ F+L D + G I++ R +K Sbjct: 82 YIVMGEKIL----KRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAK 123 >3KPX-A nrPDB Length = 198 Score = 31.2 bits (69), Expect = 0.27, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 30/59 (50%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 ++ +F +FDKD +G I +E+ T + +E F+ DL++ G + DEM Sbjct: 116 NWGEAVFDIFDKDGSGSISLDEWKTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEM 174 >4MSP-A nrPDB Length = 200 Score = 31.2 bits (69), Expect = 0.30, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 38/66 (57%), Gaps = 4/66 (6%) Query: 104 AFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGY 163 +F+ DLN D ++ DE+ + ++ G++V +E+ + V+ IF D+++DG+ Sbjct: 132 SFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVV----NESHHDALVEDIFDKEDEDKDGF 187 Query: 164 ITLDEF 169 I+ EF Sbjct: 188 ISAREF 193 >2SAS-A nrPDB Length = 185 Score = 30.8 bits (68), Expect = 0.37, Method: Compositional matrix adjust. Identities = 29/121 (23%), Positives = 53/121 (43%), Gaps = 21/121 (17%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE----KLSWAFE--------LYDLNHD 113 NH ++ D D FE+ +T ++G+L + + + E D+N D Sbjct: 21 NHDGSIQDND------FEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRDLKGRADINKD 74 Query: 114 GYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 ++++E L + S+ L A + R+ +FK MD + DG + L+EF+ Sbjct: 75 DVVSWEEYLAMWEKTIATCKSVADL---PAWCQNRIPFLFKGMDVSGDGIVDLEEFQNYC 131 Query: 174 K 174 K Sbjct: 132 K 132 >1A75-A nrPDB Length = 108 Score = 30.8 bits (68), Expect = 0.37, Method: Compositional matrix adjust. Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 7/81 (8%) Query: 52 YKQFFP----FGSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWA 104 YK FF G D F D+D +GFI +E F+ V +R + + Sbjct: 26 YKAFFAKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAF 85 Query: 105 FELYDLNHDGYITFDEMLTIV 125 + D + DG I +E + +V Sbjct: 86 LKAGDSDGDGAIGVEEWVALV 106 >4P5W-A nrPDB Length = 411 Score = 30.8 bits (68), Expect = 0.41, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Query: 43 LAREDFVKIYKQFFPFGSPEDFANHLFT-VFDKDNNGFIHFEEFITVLSTTSRGTLEEKL 101 ++ DFV Y F P L + V D+ +G I F+EF+ S + Sbjct: 57 MSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLC--APDALF 114 Query: 102 SWAFELYDLNHDGYITFDEM 121 AF+L+D G +TF+++ Sbjct: 115 MVAFQLFDKAGKGEVTFEDV 134 >1UHK-A nrPDB Length = 191 Score = 30.8 bits (68), Expect = 0.42, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 25/58 (43%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 + + LF + DKD NG I +E+ E F + D++ G + DEM Sbjct: 110 WGDALFDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEM 167 Score = 29.6 bits (65), Expect = 0.72, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 8/42 (19%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPE 146 F D+NH+G I+ DEM VYK S + +N ATPE Sbjct: 22 FNFLDVNHNGKISLDEM------VYK--ASDIVINNLGATPE 55 Score = 26.9 bits (58), Expect = 6.0, Method: Compositional matrix adjust. Identities = 10/24 (41%), Positives = 19/24 (79%) Query: 152 IFKLMDKNEDGYITLDEFREGSKV 175 +F ++DK+++G ITLDE++ +K Sbjct: 114 LFDIVDKDQNGAITLDEWKAYTKA 137 >5XOP-A nrPDB Length = 66 Score = 30.4 bits (67), Expect = 0.53, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 29/64 (45%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A LF D + +G + +EE +S E+ L F+ D + DG+I F+E Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKF 61 Query: 125 VASV 128 S+ Sbjct: 62 YGSI 65 Score = 29.6 bits (65), Expect = 0.78, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 12/65 (18%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYI 164 F+ D+N DG ++++E+ V+ + E ++ IFK +DK+ DG+I Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAI------------KNEQLLQLIFKSIDKDGDGFI 53 Query: 165 TLDEF 169 +EF Sbjct: 54 DFEEF 58 >1SJJ-A nrPDB Length = 863 Score = 30.0 bits (66), Expect = 0.55, Method: Compositional matrix adjust. Identities = 33/122 (27%), Positives = 48/122 (39%), Gaps = 14/122 (11%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F FD+ G + E+F L + E + + + D N G +TF + + Sbjct: 731 FNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPNRMGVVTFQAFIDFM--- 787 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPS--IIGALNLY 186 S T + D A M KI DKN YIT+DE R D + I + Y Sbjct: 788 -----SRETADTDTADQVMASFKILA-GDKN---YITVDELRRELPPDQAEYCIARMAPY 838 Query: 187 DG 188 +G Sbjct: 839 NG 840 >2L50-A nrPDB Length = 102 Score = 30.0 bits (66), Expect = 0.59, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 3/63 (4%) Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDE 142 +E +LS T +KL + D NHDG I+FDE T++ + + ++ E + Sbjct: 43 KELNHMLSDTGNRKAADKL---IQNLDANHDGRISFDEYWTLIGGITGPIAKLIHEQEQQ 99 Query: 143 ATP 145 ++ Sbjct: 100 SSS 102 >1OQP-A nrPDB Length = 77 Score = 30.0 bits (66), Expect = 0.60, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 25/57 (43%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F +FD DN+G I ++ V EE+L D N D I DE + I+ Sbjct: 15 FRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIM 71 >5ZI5-A nrPDB Length = 921 Score = 30.0 bits (66), Expect = 0.64, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 36/92 (39%), Gaps = 1/92 (1%) Query: 12 DLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTV 71 DL L D R +Q +R + A E I++ F E F + Sbjct: 372 DLIRLLDGKNLDERAPRQSAYTAVRSLYTAA-AYEKSADIFRMMMLFIGKEPFIEAVAKF 430 Query: 72 FDKDNNGFIHFEEFITVLSTTSRGTLEEKLSW 103 F ++ G + E+FI +S +S L LSW Sbjct: 431 FKDNDGGAVTLEDFIESISNSSGKDLRSFLSW 462 >1W7I-B nrPDB Length = 151 Score = 30.0 bits (66), Expect = 0.69, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 G+ ED+ F VFDK+ NG + E VL+T EE++ ++ + +G I + Sbjct: 84 GTYEDYLEG-FRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHE-DSNGCINY 141 Query: 119 DEMLTIVASV 128 + L + SV Sbjct: 142 EAFLKHILSV 151 >1RK9-A nrPDB Length = 110 Score = 30.0 bits (66), Expect = 0.71, Method: Compositional matrix adjust. Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 7/82 (8%) Query: 52 YKQFFPF----GSPEDFANHLFTVFDKDNNGFIHFEEFITVL---STTSRGTLEEKLSWA 104 +K+FF D +F + DKD +GFI +E +L S +R ++ Sbjct: 27 HKKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKML 86 Query: 105 FELYDLNHDGYITFDEMLTIVA 126 D + DG I DE T+VA Sbjct: 87 MAAGDKDGDGKIGVDEFSTLVA 108 >5OTJ-D nrPDB Length = 110 Score = 30.0 bits (66), Expect = 0.71, Method: Compositional matrix adjust. Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 1/86 (1%) Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 +F FD + +G I E L T + +E E+ D + DG+I F+E ++ Sbjct: 7 RIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEI-DTDGDGFIDFNEFISFCN 65 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKI 152 + +M + + + E ++ K I Sbjct: 66 ANPGLMKDVAKVFKGELNSKLEGKPI 91 Score = 27.7 bits (60), Expect = 2.9, Method: Compositional matrix adjust. Identities = 18/84 (21%), Positives = 37/84 (44%), Gaps = 13/84 (15%) Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 + + + F+ +D N DG I+ E+ + +GS T V+++ + Sbjct: 1 MADDMERIFKRFDTNGDGKISLSEL----TDALRTLGS---------TSADEVQRMMAEI 47 Query: 157 DKNEDGYITLDEFREGSKVDPSII 180 D + DG+I +EF +P ++ Sbjct: 48 DTDGDGFIDFNEFISFCNANPGLM 71 >4P5X-A nrPDB Length = 315 Score = 29.6 bits (65), Expect = 0.77, Method: Compositional matrix adjust. Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 5/81 (6%) Query: 46 EDFVKIYKQFF--PFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSW 103 EDFV+ Y + P +P+ L V D+ +G I ++EF+ S + Sbjct: 41 EDFVQRYLGLYNDPNSNPK-IVQLLAGVADQTKDGLISYQEFLAFESVLC--APDSMFIV 97 Query: 104 AFELYDLNHDGYITFDEMLTI 124 AF+L+D + +G +TF+ + I Sbjct: 98 AFQLFDKSGNGEVTFENVKEI 118 >3JBH-C nrPDB Length = 156 Score = 29.6 bits (65), Expect = 0.79, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 5/92 (5%) Query: 42 QLAREDFVKIYKQFFP---FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLE 98 +L E+F+ I+ Q G+ EDF L V+DK NG + E VL + + Sbjct: 61 KLTLEEFLPIFSQIKKEKEVGTLEDFMEGL-KVYDKAENGTMLAAELAHVLLSLGERLTD 119 Query: 99 EKLSWAFELYDLNHDGYITFDEML-TIVASVY 129 + + D + DG++ ++ + TI+A + Sbjct: 120 IECEEIMRVCDEDDDGFLKYEPFVKTIIAGPF 151 >2NCO-A nrPDB Length = 102 Score = 29.6 bits (65), Expect = 0.87, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 12/80 (15%) Query: 97 LEEKLSWA---FELYDLNHDGYITFDEMLTIVASVYKMMG--SMVTLNEDEATPEMRVKK 151 +E KL A F+ YD + G + DE+ ++ Y MG + ED VK Sbjct: 10 VEAKLDVARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKED-------VKI 62 Query: 152 IFKLMDKNEDGYITLDEFRE 171 ++ D N DG ++L+E+ + Sbjct: 63 WLQMADTNSDGSVSLEEYED 82 >2G9B-A nrPDB Length = 263 Score = 29.6 bits (65), Expect = 0.87, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 20/110 (18%) Query: 72 FDKDNNGFIHFEEFITVLS--------TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 +D D++GFI EE L T L E +L+D N+DG + EM Sbjct: 112 YDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 171 Query: 124 IVAS----VYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 ++ + K G + E K F+L D++ +GYI +E Sbjct: 172 LLPVQENFLLKFQGIKMCGKE--------FNKAFELYDQDGNGYIDENEL 213 Score = 29.3 bits (64), Expect = 1.2, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 8/67 (11%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLE--------EKLSWAFELYDLNHDG 114 ++ + + +FD +N+G + E +L L+ ++ + AFELYD + +G Sbjct: 147 EYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNG 206 Query: 115 YITFDEM 121 YI +E+ Sbjct: 207 YIDENEL 213 >3AAJ-A nrPDB Length = 167 Score = 29.3 bits (64), Expect = 0.94, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 8/70 (11%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYI--TF 118 + F + L FD+ G I F++FI + ++L+ F YD + DG+I ++ Sbjct: 103 SDQFHDILIRKFDRQGRGQIAFDDFIQGC------IVLQRLTDIFRRYDTDQDGWIQVSY 156 Query: 119 DEMLTIVASV 128 ++ L++V S+ Sbjct: 157 EQYLSMVFSI 166 >4WPX-A nrPDB Length = 177 Score = 29.3 bits (64), Expect = 0.95, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 26/67 (38%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 P D F +FD D G I ++ V + + E +D N G + DE Sbjct: 109 PRDELRRAFRLFDVDGKGMITEDDLRKVCQQVGNNIPDADIQAMIEEFDSNGKGGVDEDE 168 Query: 121 MLTIVAS 127 L ++ S Sbjct: 169 FLRLMMS 175 Score = 28.1 bits (61), Expect = 2.3, Method: Compositional matrix adjust. Identities = 10/29 (34%), Positives = 21/29 (72%) Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASV 128 ++S AFEL+D N DG ++++E ++ ++ Sbjct: 27 RISEAFELFDSNKDGLLSYEEFRFVLRAL 55 Score = 27.3 bits (59), Expect = 4.5, Method: Compositional matrix adjust. Identities = 10/23 (43%), Positives = 17/23 (73%) Query: 148 RVKKIFKLMDKNEDGYITLDEFR 170 R+ + F+L D N+DG ++ +EFR Sbjct: 27 RISEAFELFDSNKDGLLSYEEFR 49 >2AMI-A nrPDB Length = 96 Score = 29.3 bits (64), Expect = 0.95, Method: Compositional matrix adjust. Identities = 12/43 (27%), Positives = 24/43 (55%) Query: 49 VKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLST 91 +K+ + F ++ + + DKD +G I FEEF+T+++ Sbjct: 52 LKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTA 94 >2M1U-A nrPDB Length = 93 Score = 29.3 bits (64), Expect = 0.98, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F FD D +GF+ EEF ++ T E +++ FE D N+ G+I + ++ SV Sbjct: 32 FYNFDGDYDGFVSVEEFRGIIRDGLPMT-EAEITEFFEAADPNNTGFIDYKAFAAMLYSV 90 >2K2A-A nrPDB Length = 70 Score = 29.3 bits (64), Expect = 1.0, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 24/38 (63%) Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 ++++L AF LYD +GYI+ D M I+A + + + S Sbjct: 1 MQQELREAFRLYDKEGNGYISTDVMREILAELDETLSS 38 Score = 26.2 bits (56), Expect = 8.6, Method: Compositional matrix adjust. Identities = 13/57 (22%), Positives = 27/57 (47%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F ++DK+ NG+I + +L+ E L + D + G + F+E + ++ Sbjct: 9 FRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVM 65 >1DGU-A nrPDB Length = 183 Score = 29.3 bits (64), Expect = 1.0, Method: Compositional matrix adjust. Identities = 20/93 (21%), Positives = 46/93 (49%), Gaps = 9/93 (9%) Query: 43 LAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS 102 L+ EDF+ + F +P+ +++ F +FD D++G ++ E+ +++ + + +LS Sbjct: 78 LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLS 137 Query: 103 WA---------FELYDLNHDGYITFDEMLTIVA 126 + E D++ DG I E +++ Sbjct: 138 ASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 170 >5H53-C nrPDB Length = 153 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 12/87 (13%) Query: 52 YKQFFPF----------GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKL 101 ++QF P G+ EDF L VFDK+ NG + E VL+T EE++ Sbjct: 68 FEQFLPMLQAISNNKDQGTYEDFVEGL-RVFDKEGNGTVMGAELRHVLATLGEKMKEEEV 126 Query: 102 SWAFELYDLNHDGYITFDEMLTIVASV 128 A + +G I ++ + + S+ Sbjct: 127 E-ALMAGQEDSNGCINYEAFVKHIMSI 152 >2K7B-A nrPDB Length = 76 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 14/59 (23%), Positives = 29/59 (49%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F FDKD +G+I+ + + T E +L + ++N G++ FD+ + ++ Sbjct: 16 FREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGP 74 Score = 28.1 bits (61), Expect = 2.5, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 12/73 (16%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 E+L AF +D + DGYI ++ + + MG M T EM + ++ + ++ Sbjct: 10 EELREAFREFDKDKDGYINCRDL----GNCMRTMGYMPT--------EMELIELSQQINM 57 Query: 159 NEDGYITLDEFRE 171 N G++ D+F E Sbjct: 58 NLGGHVDFDDFVE 70 >2I18-A nrPDB Length = 64 Score = 28.9 bits (63), Expect = 1.2, Method: Compositional matrix adjust. Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 16/71 (22%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE 160 L ++L D++ DG +T +E V S +K G E E +K D N Sbjct: 7 LKVLYKLMDVDGDGKLTKEE----VTSFFKKHGI-------EKVAEQVMK-----ADANG 50 Query: 161 DGYITLDEFRE 171 DGYITL+EF E Sbjct: 51 DGYITLEEFLE 61 >1S6J-A nrPDB Length = 87 Score = 28.9 bits (63), Expect = 1.3, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 LF + D DN+G I F+E L +E ++ + D++ G I + E I A+ Sbjct: 28 LFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEF--IAAT 85 Query: 128 VY 129 V+ Sbjct: 86 VH 87 Score = 27.7 bits (60), Expect = 3.2, Method: Compositional matrix adjust. Identities = 11/26 (42%), Positives = 19/26 (73%) Query: 149 VKKIFKLMDKNEDGYITLDEFREGSK 174 +K++FK++D + G IT DE ++G K Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLK 50 >1IJ5-A nrPDB Length = 323 Score = 28.9 bits (63), Expect = 1.3, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 31/51 (60%), Gaps = 2/51 (3%) Query: 40 SGQLAREDFVKIYK-QFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL 89 SGQL++E+ K+ + P + + F H F+V D D++ + ++EF+ ++ Sbjct: 267 SGQLSKEEVQKVLEDAHIPESARKKF-EHQFSVVDVDDSKSLSYQEFVMLV 316 >2N7L-C nrPDB Length = 141 Score = 28.9 bits (63), Expect = 1.3, Method: Compositional matrix adjust. Identities = 19/90 (21%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 2 GAKTSKLSKDDL--TCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFG 59 G + S DD+ ++Q T + E + F+ G ++ ++ K+ + Sbjct: 8 GGLVPRGSMDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNP 67 Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVL 89 +PE+ + V D+D +G + F+EF+ ++ Sbjct: 68 TPEELQEMIDEV-DEDGSGTVDFDEFLVMM 96 >2N8Y-A nrPDB Length = 153 Score = 28.9 bits (63), Expect = 1.4, Method: Compositional matrix adjust. Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 21/109 (19%) Query: 69 FTVFDKDNNGFIHFEEFITVLST-----TSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 F FD+D++G + EEF L + + E + + + D N G +TF + Sbjct: 16 FNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFID 75 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM--DKNEDGYITLDEFR 170 + S T + D A +V FK++ DKN YIT+DE R Sbjct: 76 FM--------SRETADTDTAD---QVMASFKILAGDKN---YITMDELR 110 >2KQY-A nrPDB Length = 108 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 7/81 (8%) Query: 52 YKQFFPF----GSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWA 104 YK FF D +F + D+D +GFI EE F+ S+++R + Sbjct: 26 YKSFFSTVGLSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAF 85 Query: 105 FELYDLNHDGYITFDEMLTIV 125 D + DG I +E ++V Sbjct: 86 LAAGDTDGDGKIGVEEFQSLV 106 Score = 26.6 bits (57), Expect = 7.6, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 27/42 (64%), Gaps = 3/42 (7%) Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 YK S V L+ TP+ ++KK+F ++D+++ G+I +E + Sbjct: 26 YKSFFSTVGLSSK--TPD-QIKKVFGILDQDKSGFIEEEELQ 64 >1KYW-A nrPDB Length = 365 Score = 28.5 bits (62), Expect = 1.8, Method: Compositional matrix adjust. Identities = 17/79 (21%), Positives = 34/79 (43%) Query: 84 EFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEA 143 + + +++ G + A +L N D + D ML ++A + S+ T + + Sbjct: 43 DLLEIIAKAGPGAQISPIEIASQLPTTNPDAPVMLDRMLRLLACYIILTCSVRTQQDGKV 102 Query: 144 TPEMRVKKIFKLMDKNEDG 162 + + K + KNEDG Sbjct: 103 QRLYGLATVAKYLVKNEDG 121 >1H4B-A nrPDB Length = 84 Score = 28.5 bits (62), Expect = 1.8, Method: Compositional matrix adjust. Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 13/65 (20%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYI 164 F+ +D N DG I+ E+ K +GS+ TP+ VK + +D + DG+I Sbjct: 15 FKRFDANGDGKISAAEL----GEALKTLGSI--------TPD-EVKHMMAEIDTDGDGFI 61 Query: 165 TLDEF 169 + EF Sbjct: 62 SFQEF 66 Score = 27.7 bits (60), Expect = 3.0, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 D H+ D D +GFI F+EF T +RG L++ Sbjct: 44 DEVKHMMAEIDTDGDGFISFQEF-TDFGRANRGLLKD 79 >1CB1-A nrPDB Length = 78 Score = 28.5 bits (62), Expect = 1.9, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Query: 42 QLAREDFVKIYKQFFP--FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 QL++E+ ++ + FP P + LF DK+ +G + FEEF ++ S+ Sbjct: 25 QLSKEELKQLIQAEFPSLLKGPRTL-DDLFQELDKNGDGEVSFEEFQVLVKKISQ 78 >5Z1Q-A nrPDB Length = 95 Score = 28.1 bits (61), Expect = 2.1, Method: Compositional matrix adjust. Identities = 16/62 (25%), Positives = 26/62 (41%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FD + G I + E + + ++ YD +GYI FD+ L I+ Sbjct: 33 FDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDFLDIMTEK 92 Query: 129 YK 130 K Sbjct: 93 IK 94 Score = 26.9 bits (58), Expect = 6.0, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 18/74 (24%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM-- 156 +++ AF+L+D N G I + E+ +M L D PE I +LM Sbjct: 27 QEIKEAFDLFDTNKTGSIDYHELKV----------AMRALGFDVKKPE-----ILELMNE 71 Query: 157 -DKNEDGYITLDEF 169 D+ +GYI D+F Sbjct: 72 YDREGNGYIGFDDF 85 >1Y1X-A nrPDB Length = 191 Score = 28.1 bits (61), Expect = 2.3, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 13/74 (17%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 +E + W F D + G I+ E+ ++S G +L AT E K+ + D Sbjct: 27 QELMEW-FRAVDTDGSGAISVPELNAALSSA----GVPFSL----ATTE----KLLHMYD 73 Query: 158 KNEDGYITLDEFRE 171 KN G IT DEF++ Sbjct: 74 KNHSGEITFDEFKD 87 >2Q4U-A nrPDB Length = 272 Score = 28.1 bits (61), Expect = 2.3, Method: Compositional matrix adjust. Identities = 19/89 (21%), Positives = 42/89 (47%), Gaps = 9/89 (10%) Query: 46 EDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE--------FITVLSTTSRGTL 97 E+F+ I+++ P + +F ++ +D D++G+I E F+ L Sbjct: 88 ENFLLIFRREAPLDNSVEFMK-IWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKL 146 Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVA 126 +E +++D N DG + +++ I+A Sbjct: 147 DEYTDAMMKIFDKNKDGRLDLNDLARILA 175 Score = 27.7 bits (60), Expect = 3.3, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 6/63 (9%) Query: 108 YDLNHDGYITFDEMLTIVASVYKMMGSMVTLNE-DEATPEMRVKKIFKLMDKNEDGYITL 166 YD + GYI+ E+ + ++ + N+ DE T M K+ DKN+DG + L Sbjct: 113 YDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAM-----MKIFDKNKDGRLDL 167 Query: 167 DEF 169 ++ Sbjct: 168 NDL 170 >2JXC-A nrPDB Length = 100 Score = 28.1 bits (61), Expect = 2.5, Method: Compositional matrix adjust. Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 10/80 (12%) Query: 57 PFGSP-----EDFANHLFTVFDK--DNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYD 109 P GSP ED A + +FD NGF+ ++ VL + + L +EL D Sbjct: 2 PLGSPWAVKPEDKAKY-DAIFDSLSPVNGFLSGDKVKPVLLNSKLPV--DILGRVWELSD 58 Query: 110 LNHDGYITFDEMLTIVASVY 129 ++HDG + DE + VY Sbjct: 59 IDHDGMLDRDEFAVAMFLVY 78 >1BOD-A nrPDB Length = 74 Score = 27.7 bits (60), Expect = 2.7, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 40/73 (54%), Gaps = 12/73 (16%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVY-KMMGSMVTLNEDEATPEMRVKKIFKLMD 157 E+L FE YD DG ++ +E+ ++ + + ++ M TL+E +F+ +D Sbjct: 5 EELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTLDE-----------LFEELD 53 Query: 158 KNEDGYITLDEFR 170 KN DG ++ +EF+ Sbjct: 54 KNGDGEVSFEEFQ 66 >6D6R-C nrPDB Length = 278 Score = 27.7 bits (60), Expect = 2.7, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 2/54 (3%) Query: 100 KLSWAF--ELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKK 151 KL W +L L++DG I ++A++ + VT+NE+ A E+ +KK Sbjct: 132 KLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVNLKK 185 >3PAT-A nrPDB Length = 110 Score = 27.7 bits (60), Expect = 2.9, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 7/81 (8%) Query: 52 YKQFFPF-GSPEDFANHLFTVF---DKDNNGFIHFEEFITVL---STTSRGTLEEKLSWA 104 +K+FF G AN + VF D D +GFI EE VL + R + + Sbjct: 27 HKKFFALVGLKAMSANDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAF 86 Query: 105 FELYDLNHDGYITFDEMLTIV 125 + D + DG I DE T+V Sbjct: 87 LKAADKDGDGKIGIDEFETLV 107 >5JOJ-A nrPDB Length = 97 Score = 27.7 bits (60), Expect = 3.0, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 24/60 (40%), Gaps = 4/60 (6%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRG----TLEEKLSWAFELYDLNHDGYITFDEMLTI 124 F D D NG+I F E + + E DL+ DG I+FDE + I Sbjct: 18 FAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKI 77 Score = 27.3 bits (59), Expect = 3.9, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 20/85 (23%) Query: 93 SRGTLEEK----LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMR 148 +RG++ ++ L AF D + +GYI+F+E+ + + + P R Sbjct: 2 ARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPL------------PGYR 49 Query: 149 VKKIFK-LM---DKNEDGYITLDEF 169 V++I + LM D ++DG I+ DEF Sbjct: 50 VREITENLMATGDLDQDGRISFDEF 74 >2LVK-A nrPDB Length = 77 Score = 27.7 bits (60), Expect = 3.1, Method: Compositional matrix adjust. Identities = 18/76 (23%), Positives = 34/76 (44%), Gaps = 13/76 (17%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYI 164 F+ +D N DG I+ E+ + +GS T V+++ +D + DG+I Sbjct: 8 FKRFDTNGDGKISLSEL----TDALRTLGS---------TSADEVQRMMAEIDTDGDGFI 54 Query: 165 TLDEFREGSKVDPSII 180 +EF +P ++ Sbjct: 55 DFNEFISFCNANPGLM 70 >4D1E-A nrPDB Length = 876 Score = 27.7 bits (60), Expect = 3.2, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 23/54 (42%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F FD+ NG + E+F L + E + + L D N G +TF + Sbjct: 744 FNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTVTFQSFI 797 >1SR6-C nrPDB Length = 156 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 4/68 (5%) Query: 64 FANHL--FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHD--GYITFD 119 FA+++ F FD++ GFI E VL+ +E + +L DL D G + ++ Sbjct: 83 FADYMEAFKTFDREGQGFISGAELRHVLTALGERLSDEDVDEIIKLTDLQEDLEGNVKYE 142 Query: 120 EMLTIVAS 127 + + V + Sbjct: 143 DFVKKVMA 150 >4L9M-A nrPDB Length = 559 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 19/98 (19%) Query: 57 PFGSPEDFANHL-------FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYD 109 P P+ + H+ F +D D +G+I EEF + ++ ++F + D Sbjct: 412 PKPDPKTISKHVQRMVDSVFKNYDHDQDGYISQEEFEKIAAS---------FPFSFCVMD 462 Query: 110 LNHDGYITFDEMLTI---VASVYKMMGSMVTLNEDEAT 144 + +G I+ DE+ +S+Y +G N E T Sbjct: 463 KDREGLISRDEITAYFMRASSIYSKLGLGFPHNFQETT 500 >5JOL-A nrPDB Length = 82 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 24/60 (40%), Gaps = 4/60 (6%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRG----TLEEKLSWAFELYDLNHDGYITFDEMLTI 124 F D D NG+I F E + + E DL+ DG I+FDE + I Sbjct: 18 FAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKI 77 Score = 27.3 bits (59), Expect = 4.2, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 20/85 (23%) Query: 93 SRGTLEEK----LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMR 148 +RG++ ++ L AF D + +GYI+F+E+ + + + P R Sbjct: 2 ARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPL------------PGYR 49 Query: 149 VKKIFK-LM---DKNEDGYITLDEF 169 V++I + LM D ++DG I+ DEF Sbjct: 50 VREITENLMATGDLDQDGRISFDEF 74 >2BL0-B nrPDB Length = 145 Score = 27.3 bits (59), Expect = 3.6, Method: Compositional matrix adjust. Identities = 28/110 (25%), Positives = 44/110 (40%), Gaps = 15/110 (13%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM- 121 D F +FDKDN+G + EE + L + + +L+ G + E Sbjct: 5 DQIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTI--------KGQLNAKEFD 56 Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 L +VY+ T E + EM F+ +DK +G I E R+ Sbjct: 57 LATFKTVYRKPIKTPT----EQSKEML--DAFRALDKEGNGTIQEAELRQ 100 >3CS1-A nrPDB Length = 219 Score = 27.3 bits (59), Expect = 3.7, Method: Compositional matrix adjust. Identities = 27/138 (19%), Positives = 52/138 (37%), Gaps = 35/138 (25%) Query: 67 HLFTVFDKDNNG-------------FIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHD 113 LF FDK+ G + +EF + + ++ ++ + +L + + Sbjct: 52 ELFKKFDKNETGKLCYDEVYSGCLEVLKLDEFTSRVRDITKRAFDKSRTLGSKLENKGSE 111 Query: 114 GYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKK---------------------- 151 ++ F E ++ +Y V +E +A+ M V + Sbjct: 112 DFVEFLEFRLMLCYIYDFFELTVMFDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAA 171 Query: 152 IFKLMDKNEDGYITLDEF 169 +FK +DKN G +T DEF Sbjct: 172 LFKELDKNGTGSVTFDEF 189 >6IIE-A nrPDB Length = 93 Score = 27.3 bits (59), Expect = 4.1, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 4/87 (4%) Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 G E+KL + F+LYD + +G + E+ I + +MM L+ D + ++++ K Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKI---ILQMMRVAEYLDWDVSELRPILQEMMK 61 Query: 155 LMDKNEDGYITLDEF-REGSKVDPSII 180 +D + G ++ E+ R G+ P ++ Sbjct: 62 EIDYDGSGSVSQAEWVRAGATTVPLLV 88 Score = 26.2 bits (56), Expect = 8.8, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 2/45 (4%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSW 103 G PED F ++D D NG + E ++ R + E L W Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMR--VAEYLDW 47 >2JOJ-A nrPDB Length = 77 Score = 27.3 bits (59), Expect = 4.2, Method: Compositional matrix adjust. Identities = 16/62 (25%), Positives = 26/62 (41%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FD + G I + E + + ++ YD +GYI FD+ L I+ Sbjct: 13 FDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDFLDIMTEK 72 Query: 129 YK 130 K Sbjct: 73 IK 74 >3A8R-A nrPDB Length = 179 Score = 27.3 bits (59), Expect = 4.5, Method: Compositional matrix adjust. Identities = 10/24 (41%), Positives = 17/24 (70%) Query: 148 RVKKIFKLMDKNEDGYITLDEFRE 171 R++ F ++DKN DG +T +E +E Sbjct: 99 RLRTFFDMVDKNADGRLTAEEVKE 122 >4OCI-A nrPDB Length = 146 Score = 26.9 bits (58), Expect = 4.8, Method: Compositional matrix adjust. Identities = 18/80 (22%), Positives = 33/80 (41%) Query: 43 LAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS 102 ++ E F + Q +D V DKD GFI E +LST +++++ Sbjct: 57 MSYELFTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEIT 116 Query: 103 WAFELYDLNHDGYITFDEML 122 F ++ G + D+ + Sbjct: 117 DLFTFMGIDEQGVVKVDDFI 136 >5VLN-A nrPDB Length = 120 Score = 26.9 bits (58), Expect = 5.1, Method: Compositional matrix adjust. Identities = 15/76 (19%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Query: 14 TCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 ++Q T + E + F+ G ++ ++ K+ + +PE+ + V D Sbjct: 7 AAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEV-D 65 Query: 74 KDNNGFIHFEEFITVL 89 +D +G + F+EF+ ++ Sbjct: 66 EDGSGTVDFDEFLVMM 81 >2VRG-A nrPDB Length = 124 Score = 26.9 bits (58), Expect = 5.1, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 14/72 (19%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD------- 157 F+++D + + + E+ T + V+K GS E P M ++ ++D Sbjct: 55 FKMHDYDGNNLLDGLELSTAITHVHKEEGS-------EQAPLMSEDELINIIDGVLRDDD 107 Query: 158 KNEDGYITLDEF 169 KN DGYI EF Sbjct: 108 KNNDGYIDYAEF 119 >4GJF-A nrPDB Length = 89 Score = 26.9 bits (58), Expect = 5.4, Method: Compositional matrix adjust. Identities = 15/76 (19%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Query: 14 TCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 ++Q T + E + F++ G ++ ++ K+ + +PE+ + V D Sbjct: 7 AAVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEV-D 65 Query: 74 KDNNGFIHFEEFITVL 89 +D +G + F+EF+ ++ Sbjct: 66 EDGSGTVDFDEFLVMM 81 >3LCP-C nrPDB Length = 93 Score = 26.9 bits (58), Expect = 5.6, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 14/72 (19%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD------- 157 F+++D + + + E+ T + V+K GS E P M ++ ++D Sbjct: 24 FKMHDYDGNNLLDGLELSTAITHVHKEEGS-------EQAPLMSEDELINIIDGVLRDDD 76 Query: 158 KNEDGYITLDEF 169 KN DGYI EF Sbjct: 77 KNNDGYIDYAEF 88 >4PAL-A nrPDB Length = 108 Score = 26.9 bits (58), Expect = 6.0, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 69 FTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F V D+D +GFI +E F+ S ++R + + D + DG I DE ++ Sbjct: 47 FYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLADGDKDGDGMIGVDEFAAMI 106 >3A4U-B nrPDB Length = 143 Score = 26.6 bits (57), Expect = 6.1, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 14/72 (19%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD------- 157 F+++D + + + E+ T + V+K GS E P M ++ ++D Sbjct: 74 FKMHDYDGNNLLDGLELSTAITHVHKEEGS-------EQAPLMSEDELINIIDGVLRDDD 126 Query: 158 KNEDGYITLDEF 169 KN DGYI EF Sbjct: 127 KNNDGYIDYAEF 138 >3I6D-A nrPDB Length = 470 Score = 26.6 bits (57), Expect = 6.8, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 23/49 (46%) Query: 89 LSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 L+ +GT KLS + Y L D +T D IV + +K M++ Sbjct: 247 LTKVYKGTKVTKLSHSGSCYSLELDNGVTLDADSVIVTAPHKAAAGMLS 295 >3SIA-A nrPDB Length = 220 Score = 26.6 bits (57), Expect = 6.9, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 8/66 (12%) Query: 26 EIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFG---SPEDFANHLFTVFDKDNNGFIHF 82 I QW G RD SG L + ++ FP G SP+ A + +FD D NG I F Sbjct: 52 RIYQWFMGVDRD-RSGTL---EINELMMGQFPGGIRLSPQT-ALRMMRIFDTDFNGHISF 106 Query: 83 EEFITV 88 EF+ + Sbjct: 107 YEFMAM 112 >5DGE-C0 nrPDB Length = 105 Score = 26.6 bits (57), Expect = 7.2, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 12/94 (12%) Query: 43 LAREDFVKIYKQFFPFG---SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 + +ED KI++ F G + +DF D N I + S TS+G ++ Sbjct: 3 MPKEDRNKIHQYLFQEGVVVAKKDFNQAKHEEIDTKNLYVIK-----ALQSLTSKGYVKT 57 Query: 100 KLSWAFELYDLNHDGYITFDEMLT----IVASVY 129 + SW + Y L +G E L IV + Y Sbjct: 58 QFSWQYYYYTLTEEGVEYLREYLNLPEHIVPATY 91 >4YGB-B nrPDB Length = 104 Score = 26.2 bits (56), Expect = 8.3, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 14/72 (19%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD------- 157 F+++D + + + E+ T + V+K GS E P M ++ ++D Sbjct: 35 FKMHDYDGNNLLDGLELSTAITHVHKEEGS-------EQAPLMSEDELINIIDGVLRDDD 87 Query: 158 KNEDGYITLDEF 169 KN DGYI EF Sbjct: 88 KNNDGYIDYAEF 99 >4MVF-A nrPDB Length = 506 Score = 26.2 bits (56), Expect = 9.0, Method: Compositional matrix adjust. Identities = 28/132 (21%), Positives = 54/132 (40%), Gaps = 15/132 (11%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 SG L+ ++ + K+ P D L + D + +G IH+ +F+ +E Sbjct: 374 SGTLSSQEILDGLKKIGYQKIPPDIHQVLRDI-DSNASGQIHYTDFLAATIDKQTYLKKE 432 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATP--EMRVKKIFKLMD 157 F+ +D++ +G I+ +E+ I +D P + + + + +D Sbjct: 433 VCLIPFKFFDIDGNGKISVEELKRIFGR------------DDIENPLIDKAIDSLLQEVD 480 Query: 158 KNEDGYITLDEF 169 N DG I EF Sbjct: 481 LNGDGEIDFHEF 492 >1Q80-A nrPDB Length = 174 Score = 26.2 bits (56), Expect = 9.9, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 14/82 (17%) Query: 88 VLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEM 147 V + ++ +E L F D N D I+ DE Y + M+ L++ A Sbjct: 83 VKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDE--------YGIFFGMLGLDKTMAPAS- 133 Query: 148 RVKKIFKLMDKNEDGYITLDEF 169 F +D N DG ++L+EF Sbjct: 134 -----FDAIDTNNDGLLSLEEF 150 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2JU0-A nrPDB 245 8e-66 2LCP-A nrPDB 226 3e-60 2L2E-A nrPDB 226 5e-60 5T7C-A nrPDB 226 5e-60 1BJF-A nrPDB 223 4e-59 5M6C-E nrPDB 219 4e-58 2JUL-A nrPDB 212 1e-55 6EPA-A nrPDB 205 1e-53 3DD4-A nrPDB 199 5e-52 1S6C-A nrPDB 197 2e-51 1S1E-A nrPDB 196 5e-51 2I94-A nrPDB 182 9e-47 2D8N-A nrPDB 175 1e-44 1JBA-A nrPDB 154 2e-38 2R2I-A nrPDB 153 4e-38 2NA0-A nrPDB 149 6e-37 2GGZ-A nrPDB 137 3e-33 2ZFD-A nrPDB 134 3e-32 1UHN-A nrPDB 129 7e-31 4IL1-A nrPDB 129 9e-31 1V1G-A nrPDB 126 7e-30 3HZT-A nrPDB 122 1e-28 5YPX-A nrPDB 115 8e-27 4ORC-B nrPDB 115 1e-26 4OY4-A nrPDB 113 4e-26 3U0K-A nrPDB 113 4e-26 5JN2-A nrPDB 112 1e-25 3EK4-A nrPDB 111 2e-25 3KHE-A nrPDB 109 7e-25 4YZB-A nrPDB 109 9e-25 5B8I-B nrPDB 108 1e-24 5UKG-A nrPDB 108 1e-24 4I2Y-A nrPDB 107 2e-24 2LM5-A nrPDB 107 3e-24 2E6W-A nrPDB 107 3e-24 3LIJ-A nrPDB 107 3e-24 3Q5I-A nrPDB 107 3e-24 4RGJ-A nrPDB 106 6e-24 3NCG-A nrPDB 103 6e-23 3WFN-B nrPDB 101 2e-22 2N6A-A nrPDB 101 2e-22 3L19-A nrPDB 99 9e-22 6O20-F nrPDB 98 2e-21 2F2P-A nrPDB 98 2e-21 1DTL-A nrPDB 97 3e-21 4E53-A nrPDB 96 8e-21 6HCS-A nrPDB 95 1e-20 2E30-A nrPDB 92 1e-19 1GGZ-A nrPDB 92 1e-19 5I0I-E nrPDB 92 2e-19 5A2H-A nrPDB 90 6e-19 1CLM-A nrPDB 89 9e-19 2LHI-A nrPDB 88 2e-18 2AAO-A nrPDB 88 2e-18 4JWQ-A nrPDB 86 8e-18 1TOP-A nrPDB 85 2e-17 2TN4-A nrPDB 85 2e-17 2L1W-A nrPDB 85 2e-17 3K21-A nrPDB 84 3e-17 3O4Y-A nrPDB 84 3e-17 1LKJ-A nrPDB 84 5e-17 4DS7-A nrPDB 82 1e-16 2LHH-A nrPDB 82 1e-16 5MWC-D nrPDB 82 2e-16 3QRX-A nrPDB 81 2e-16 2BEC-A nrPDB 81 3e-16 1S6I-A nrPDB 80 4e-16 5E37-A nrPDB 77 3e-15 2LMV-A nrPDB 77 4e-15 2LC5-A nrPDB 73 9e-14 2LV7-A nrPDB 72 2e-13 2KSZ-A nrPDB 65 1e-11 1JC2-A nrPDB 63 9e-11 2M97-A nrPDB 63 9e-11 5ZGM-A nrPDB 62 2e-10 1OZS-A nrPDB 58 2e-09 1YX7-A nrPDB 52 2e-07 Sequences not found previously or not previously below threshold: 1DGU-A nrPDB 98 2e-21 5H7D-E nrPDB 79 9e-16 5COC-A nrPDB 79 2e-15 4Q57-A nrPDB 74 3e-14 3IFK-A nrPDB 74 4e-14 2I08-A nrPDB 74 4e-14 2RO8-A nrPDB 73 1e-13 2LAP-A nrPDB 72 2e-13 3KF9-A nrPDB 72 2e-13 2GGM-A nrPDB 69 1e-12 3E3R-A nrPDB 68 3e-12 5D43-A nrPDB 67 3e-12 2M29-A nrPDB 67 5e-12 2AMI-A nrPDB 66 8e-12 5ZOR-A nrPDB 66 9e-12 2OBH-A nrPDB 64 4e-11 1F55-A nrPDB 64 4e-11 1TNP-A nrPDB 63 8e-11 1TRF-A nrPDB 63 8e-11 2HF5-A nrPDB 63 9e-11 2KN2-A nrPDB 62 1e-10 2KZ2-A nrPDB 62 2e-10 1FW4-A nrPDB 61 2e-10 2BL0-B nrPDB 61 3e-10 2JNF-A nrPDB 60 4e-10 1Y1X-A nrPDB 60 6e-10 4N5X-A nrPDB 60 7e-10 4ZCV-A nrPDB 60 8e-10 1JFJ-A nrPDB 59 1e-09 2RO9-A nrPDB 59 1e-09 2JNX-A nrPDB 59 1e-09 2ROB-A nrPDB 59 1e-09 2BL0-C nrPDB 59 2e-09 2M5E-A nrPDB 58 3e-09 5VLN-A nrPDB 57 3e-09 2B1U-A nrPDB 57 4e-09 5PAL-A nrPDB 57 4e-09 2N7L-C nrPDB 57 5e-09 5Z1Q-A nrPDB 57 7e-09 4WPX-A nrPDB 56 8e-09 1S36-A nrPDB 56 9e-09 4MVF-A nrPDB 56 9e-09 5OTJ-D nrPDB 56 1e-08 1JF0-A nrPDB 55 1e-08 1ZMZ-A nrPDB 54 3e-08 2JOJ-A nrPDB 54 3e-08 3AAJ-A nrPDB 54 4e-08 4GJF-A nrPDB 54 5e-08 2LVK-A nrPDB 54 6e-08 3FWC-A nrPDB 53 8e-08 5XND-A nrPDB 53 1e-07 2OPO-A nrPDB 52 1e-07 3KPX-A nrPDB 52 1e-07 1S6J-A nrPDB 52 1e-07 1C7W-A nrPDB 52 1e-07 3PM8-A nrPDB 52 1e-07 2HPS-A nrPDB 52 2e-07 1M39-A nrPDB 52 2e-07 1W7I-B nrPDB 52 2e-07 2K7C-A nrPDB 52 2e-07 1H4B-A nrPDB 51 3e-07 5VE9-A nrPDB 51 3e-07 4P5W-A nrPDB 51 3e-07 3MSE-B nrPDB 51 4e-07 6IIE-A nrPDB 50 4e-07 5XOP-A nrPDB 50 6e-07 2Q4U-A nrPDB 50 7e-07 2KQY-A nrPDB 49 1e-06 1UHK-A nrPDB 49 1e-06 1SL8-A nrPDB 49 1e-06 2G9B-A nrPDB 49 1e-06 5B7X-A nrPDB 49 1e-06 4NQG-A nrPDB 49 2e-06 2MA2-A nrPDB 48 2e-06 5JOJ-A nrPDB 48 2e-06 5JOL-A nrPDB 48 3e-06 1OQP-A nrPDB 48 3e-06 2VRG-A nrPDB 48 3e-06 2M7M-A nrPDB 48 3e-06 3LCP-C nrPDB 48 3e-06 4YGB-B nrPDB 48 3e-06 3J04-B nrPDB 48 3e-06 3A4U-B nrPDB 47 3e-06 2K7B-A nrPDB 47 3e-06 5ZH6-A nrPDB 47 3e-06 3AKA-A nrPDB 47 5e-06 4P5X-A nrPDB 47 6e-06 3PAT-A nrPDB 47 6e-06 2K2I-A nrPDB 47 6e-06 1RTP-1 nrPDB 47 6e-06 1NYA-A nrPDB 47 7e-06 2SAS-A nrPDB 46 9e-06 4MSP-A nrPDB 46 1e-05 2KYF-A nrPDB 45 1e-05 1TTX-A nrPDB 45 2e-05 1G33-A nrPDB 45 2e-05 3I5H-B nrPDB 45 2e-05 2NLN-A nrPDB 45 2e-05 2K2A-A nrPDB 45 2e-05 1BU3-A nrPDB 45 2e-05 4D1E-A nrPDB 45 2e-05 1A75-A nrPDB 45 2e-05 6FSA-D nrPDB 44 3e-05 3JAX-C nrPDB 44 3e-05 1RK9-A nrPDB 44 3e-05 2M8U-A nrPDB 44 3e-05 1JUO-A nrPDB 44 4e-05 5TBY-C nrPDB 43 5e-05 2NCO-A nrPDB 43 7e-05 5MRA-A nrPDB 43 8e-05 4PAL-A nrPDB 43 8e-05 2MBX-A nrPDB 43 8e-05 2W4G-C nrPDB 43 9e-05 3CS1-A nrPDB 43 9e-05 5CPV-A nrPDB 43 1e-04 2PMY-A nrPDB 42 1e-04 2M1U-A nrPDB 42 1e-04 1SJJ-A nrPDB 42 1e-04 5I2L-A nrPDB 42 1e-04 1QXP-A nrPDB 42 1e-04 3TZ1-A nrPDB 42 2e-04 6EAZ-A nrPDB 42 2e-04 1KFX-S nrPDB 42 2e-04 5E1J-A nrPDB 42 2e-04 1I84-U nrPDB 42 2e-04 1TIZ-A nrPDB 42 2e-04 4L9M-A nrPDB 41 3e-04 1IJ5-A nrPDB 41 3e-04 1O1A-B nrPDB 41 3e-04 3SIA-A nrPDB 41 3e-04 2N8Y-A nrPDB 41 4e-04 4OKH-A nrPDB 41 4e-04 5TBY-E nrPDB 40 4e-04 6AGH-A nrPDB 40 5e-04 1GJY-A nrPDB 40 6e-04 5H53-B nrPDB 40 6e-04 5H53-C nrPDB 40 6e-04 1N2D-A nrPDB 40 6e-04 3DTP-E nrPDB 40 8e-04 6MI5-X nrPDB 40 9e-04 1SR6-C nrPDB 39 0.001 3JBH-C nrPDB 39 0.001 3BOW-B nrPDB 39 0.002 4I5L-B nrPDB 38 0.002 4MEW-A nrPDB 37 0.004 3DF0-A nrPDB 37 0.004 2FCE-A nrPDB 37 0.004 3A8R-A nrPDB 37 0.005 5MKE-A nrPDB 37 0.005 1WY9-A nrPDB 37 0.005 6D1W-A nrPDB 37 0.005 3I5I-C nrPDB 37 0.005 2I18-A nrPDB 37 0.006 2OS8-B nrPDB 36 0.008 2KGR-A nrPDB 36 0.008 3TS5-B nrPDB 36 0.009 1Q80-A nrPDB 36 0.009 2LVV-A nrPDB 36 0.010 4OCI-A nrPDB 35 0.014 2EC6-B nrPDB 35 0.014 1BOD-A nrPDB 35 0.017 4NSC-A nrPDB 35 0.018 1CB1-A nrPDB 35 0.024 2LUC-A nrPDB 35 0.025 1F4Q-A nrPDB 35 0.026 1QX2-A nrPDB 35 0.027 2G2B-A nrPDB 34 0.030 1GGW-A nrPDB 34 0.033 2L50-A nrPDB 34 0.035 6AGI-A nrPDB 34 0.049 1B7T-Y nrPDB 33 0.051 6DU8-A nrPDB 33 0.058 5X2E-A nrPDB 33 0.060 1NSH-A nrPDB 33 0.064 1QLS-A nrPDB 33 0.068 1DFK-Y nrPDB 33 0.068 4C0K-A nrPDB 33 0.069 1NP8-A nrPDB 33 0.075 4I5K-A nrPDB 33 0.080 1KQV-A nrPDB 33 0.090 5W1A-B nrPDB 33 0.10 5NRM-B nrPDB 32 0.12 5CUY-A nrPDB 32 0.13 5LXV-B nrPDB 32 0.14 5NRK-B nrPDB 32 0.16 2MHH-A nrPDB 32 0.16 2KHN-A nrPDB 32 0.17 1ZFS-A nrPDB 32 0.18 1SNL-A nrPDB 32 0.23 1OHZ-B nrPDB 32 0.24 1NUB-A nrPDB 31 0.26 2D58-A nrPDB 31 0.27 6DS2-B nrPDB 31 0.32 5VT9-A nrPDB 31 0.32 5C5V-A nrPDB 31 0.36 6EMI-A nrPDB 31 0.38 5CUU-A nrPDB 30 0.48 5G6V-A nrPDB 30 0.49 2VTG-A nrPDB 30 0.51 3FSR-A nrPDB 30 0.58 3FPC-A nrPDB 30 0.58 1YKF-A nrPDB 30 0.58 2AUC-A nrPDB 30 0.61 2JXC-A nrPDB 30 0.62 6QAA-A nrPDB 30 0.66 5KU1-A nrPDB 30 0.77 2MJW-B nrPDB 30 0.81 1DJX-A nrPDB 30 0.86 2L0P-A nrPDB 29 0.95 5CSF-A nrPDB 29 1.0 2K60-A nrPDB 29 1.2 2JQ6-A nrPDB 29 1.2 3H4S-E nrPDB 29 1.3 2WCE-A nrPDB 29 1.4 2KLD-A nrPDB 29 1.4 1QJT-A nrPDB 28 1.7 2KFH-A nrPDB 28 1.8 4YBH-B nrPDB 28 1.9 6J79-A nrPDB 28 1.9 1SRA-A nrPDB 28 1.9 1C07-A nrPDB 28 2.0 4L9O-A nrPDB 28 2.0 4PCW-A nrPDB 28 2.3 1KFU-L nrPDB 28 2.5 2M7L-A nrPDB 28 2.6 4G7U-A nrPDB 28 3.0 5ZDH-A nrPDB 28 3.1 5HYD-A nrPDB 28 3.1 5NPF-A nrPDB 28 3.3 5JMV-A nrPDB 28 3.4 2L5Y-A nrPDB 28 3.4 4MEC-A nrPDB 28 3.5 3B97-A nrPDB 28 3.5 5VP3-A nrPDB 27 3.8 2KQ6-A nrPDB 27 4.0 5X2G-A nrPDB 27 4.3 5AHV-F nrPDB 27 4.4 5W2O-A nrPDB 27 4.5 2QPT-A nrPDB 27 4.7 6EHA-A nrPDB 27 5.1 1ZQ1-C nrPDB 27 5.2 2KAY-A nrPDB 27 5.4 2YIK-A nrPDB 27 5.5 5OLW-A nrPDB 27 6.1 5TFQ-A nrPDB 27 6.2 5N1Q-C nrPDB 27 6.3 1Y4C-A nrPDB 27 7.1 1Z1W-A nrPDB 27 7.2 1FI6-A nrPDB 27 7.4 4EVF-A nrPDB 27 7.7 5HLO-A nrPDB 26 8.6 1J7Q-A nrPDB 26 9.2 2HVQ-A nrPDB 26 9.3 4MN0-A nrPDB 26 9.5 2Y5I-A nrPDB 26 9.5 >2JU0-A nrPDB Length = 190 Score = 245 bits (626), Expect = 8e-66, Method: Composition-based stats. Identities = 190/190 (100%), Positives = 190/190 (100%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS Sbjct: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE Sbjct: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII Sbjct: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 Query: 181 GALNLYDGLI 190 GALNLYDGLI Sbjct: 181 GALNLYDGLI 190 >2LCP-A nrPDB Length = 190 Score = 226 bits (577), Expect = 3e-60, Method: Composition-based stats. Identities = 114/190 (60%), Positives = 144/190 (75%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 MG SKL + + L + TYF +E+QQW+KGF++DCPSGQL F KIYKQFFPFG Sbjct: 1 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 60 Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 P FA +F VFD++ +G I F EFI LS TSRGTL+EKL WAF+LYDL++DGYIT +E Sbjct: 61 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 120 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 ML IV ++Y+M+G+ V L E+E TPE RV +IF +MDKN DG +TL EF+EGSK DPSI+ Sbjct: 121 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIV 180 Query: 181 GALNLYDGLI 190 AL+LYDGL+ Sbjct: 181 QALSLYDGLV 190 >2L2E-A nrPDB Length = 190 Score = 226 bits (576), Expect = 5e-60, Method: Composition-based stats. Identities = 118/189 (62%), Positives = 149/189 (78%) Query: 2 GAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP 61 G SKLS+D L L +ST FD++E+QQW+KGF +DCPSG L + +F KIYKQFFPFG P Sbjct: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 FA ++F VFD D NG+I F+EFI LS TSRG L +KL WAF+LYDL+++G I++DEM Sbjct: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIG 181 L IV ++YKM+GSMV L EDE TPE RV KIF +MDKN+DG +TL+EF EGSK DP+I+ Sbjct: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 Query: 182 ALNLYDGLI 190 AL+LYDGL+ Sbjct: 182 ALSLYDGLV 190 >5T7C-A nrPDB Length = 193 Score = 226 bits (575), Expect = 5e-60, Method: Composition-based stats. Identities = 93/183 (50%), Positives = 127/183 (69%) Query: 2 GAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP 61 G + SKL + L L+++T F E+Q+W+KGFL+DCP+G L ++F KIY FFP+G Sbjct: 2 GKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDA 61 Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 FA H+F FD + +G I F EFI LS TSRG LE+KL WAF +YDL+ +GYI+ EM Sbjct: 62 SKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEM 121 Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIG 181 L IV ++YKM+ S++ + EDE+TPE R KIF+ MD N DG ++L+EF G+K DPSI+ Sbjct: 122 LEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVR 181 Query: 182 ALN 184 L Sbjct: 182 LLQ 184 >1BJF-A nrPDB Length = 193 Score = 223 bits (568), Expect = 4e-59, Method: Composition-based stats. Identities = 98/184 (53%), Positives = 129/184 (70%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 MG + SKL + + L +ST F EIQ+W+KGFLRDCPSG L+ E+F KIY FFP+G Sbjct: 1 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD 60 Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 FA H+F FD + +G I F EFI LS TSRG LE+KL WAF +YDL+ +GYI+ E Sbjct: 61 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE 120 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 ML IV ++YKM+ S++ + EDE+TPE R +KIF+ MD N DG ++L+EF G+K DPSI+ Sbjct: 121 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIV 180 Query: 181 GALN 184 L Sbjct: 181 RLLQ 184 >5M6C-E nrPDB Length = 193 Score = 219 bits (559), Expect = 4e-58, Method: Composition-based stats. Identities = 94/184 (51%), Positives = 131/184 (71%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 MG + SKL + L L+++T F E+Q+W+KGFL+DCP+G L ++F KIY FFP+G Sbjct: 1 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGD 60 Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 FA H+F FD +++G I F EFI LS TSRG LE+KL WAF +YDL+ +GYI+ +E Sbjct: 61 ASKFAEHVFRNFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREE 120 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 ML IV ++YKM+ S++ + EDE+TPE R +KIF+ MD N DG ++L+EF G+K DPSI+ Sbjct: 121 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV 180 Query: 181 GALN 184 L Sbjct: 181 RLLQ 184 >2JUL-A nrPDB Length = 256 Score = 212 bits (539), Expect = 1e-55, Method: Composition-based stats. Identities = 79/187 (42%), Positives = 115/187 (61%) Query: 4 KTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPED 63 T + + L L+ T F ++E+Q ++GF +CP+G + + F IY QFFP G Sbjct: 70 STVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATT 129 Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 +A+ LF FD D NG IHFE+F+ LS RGT+ EKL WAF LYD+N DG IT +EML Sbjct: 130 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGAL 183 I+ S+Y MMG E P V++ F+ MD+N+DG +T+DEF E + D +I+ ++ Sbjct: 190 IMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSM 249 Query: 184 NLYDGLI 190 L++ +I Sbjct: 250 QLFENVI 256 >6EPA-A nrPDB Length = 187 Score = 205 bits (521), Expect = 1e-53, Method: Composition-based stats. Identities = 107/185 (57%), Positives = 135/185 (72%), Gaps = 1/185 (0%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 MG K SKL +D + L TYF +EI+QWHKGFL+DCP+G L + F+KIYKQFFP G Sbjct: 1 MGKKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGD 60 Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 P FA+ +F VFD++N+G I FEEFI LS TSRG L+EKL WAF LYD+++DGYIT +E Sbjct: 61 PSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREE 120 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 M IV ++Y+M+G EDE TP+ RV KIF MDKN D +TL+EFREGSK DP ++ Sbjct: 121 MYNIVDAIYQMVGQQPQ-TEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMV 179 Query: 181 GALNL 185 AL+L Sbjct: 180 QALSL 184 >3DD4-A nrPDB Length = 229 Score = 199 bits (507), Expect = 5e-52, Method: Composition-based stats. Identities = 80/186 (43%), Positives = 118/186 (63%) Query: 5 TSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDF 64 T + + L L+ + F ++E+Q ++GF +CPSG + E F +IY QFFP G + Sbjct: 44 TVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTY 103 Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A+ LF FD D+NG + FE+FI LS RGT++EKL+WAF LYD+N DGYIT +EML I Sbjct: 104 AHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDI 163 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALN 184 + ++Y MMG E P V+ F+ MDKN+DG +T+DEF E + D +I+ ++ Sbjct: 164 MKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQ 223 Query: 185 LYDGLI 190 L++ +I Sbjct: 224 LFENVI 229 >1S6C-A nrPDB Length = 183 Score = 197 bits (501), Expect = 2e-51, Method: Composition-based stats. Identities = 79/183 (43%), Positives = 110/183 (60%) Query: 8 LSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANH 67 + L L+ T F +RE+Q ++GF +CPSG + E F +IY QFFP G +A++ Sbjct: 1 HRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHY 60 Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 LF FD G + FE+F+T LS RGT+ EKL W F LYD+N DGYI +EM+ IV + Sbjct: 61 LFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKA 120 Query: 128 VYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYD 187 +Y MMG E TP V F+ MDKN+DG +TLDEF E + D +I+ +L L+ Sbjct: 121 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQ 180 Query: 188 GLI 190 ++ Sbjct: 181 NVM 183 >1S1E-A nrPDB Length = 224 Score = 196 bits (498), Expect = 5e-51, Method: Composition-based stats. Identities = 79/183 (43%), Positives = 110/183 (60%) Query: 8 LSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANH 67 + L L+ T F +RE+Q ++GF +CPSG + E F +IY QFFP G +A++ Sbjct: 34 HRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHY 93 Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 LF FD G + FE+F+T LS RGT+ EKL W F LYD+N DGYI +EM+ IV + Sbjct: 94 LFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKA 153 Query: 128 VYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYD 187 +Y MMG E TP V F+ MDKN+DG +TLDEF E + D +I+ +L L+ Sbjct: 154 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQ 213 Query: 188 GLI 190 ++ Sbjct: 214 NVM 216 >2I94-A nrPDB Length = 202 Score = 182 bits (461), Expect = 9e-47, Method: Composition-based stats. Identities = 73/187 (39%), Positives = 117/187 (62%), Gaps = 3/187 (1%) Query: 1 MG-AKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFG 59 MG +K+ LSK+ L L+ +T F E+ W++ FL++CPSG++ R++F IY +FFP Sbjct: 1 MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEA 60 Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 P+ +A H+F FD +++G + F+E++ L TS G +KL WAF LYD++ +G I+ + Sbjct: 61 DPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKN 120 Query: 120 EMLTIVASVYKMMGSMVT--LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDP 177 E+L IV +++KM+ T L EDE TPE R +KI+ K +D +T EF EG+ + Sbjct: 121 EVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIEGTLANK 180 Query: 178 SIIGALN 184 I+ + Sbjct: 181 EILRLIQ 187 >2D8N-A nrPDB Length = 207 Score = 175 bits (443), Expect = 1e-44, Method: Composition-based stats. Identities = 68/180 (37%), Positives = 111/180 (61%), Gaps = 2/180 (1%) Query: 7 KLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFAN 66 LSK+ L L+ +T F E+ W++ FL+DCP+G++ ++ F IY +FFP P+ +A Sbjct: 15 ALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQ 74 Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 H+F FD + +G + F+E++ L T+ G +KL WAF LYD++ +G I+ +E+L IV Sbjct: 75 HVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVM 134 Query: 127 SVYKMMGSMVT--LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALN 184 +++KM+ L +DE TPE R +KI+K KN+D +T EF EG+ + I+ + Sbjct: 135 AIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQ 194 >1JBA-A nrPDB Length = 204 Score = 154 bits (389), Expect = 2e-38, Method: Composition-based stats. Identities = 63/189 (33%), Positives = 100/189 (52%), Gaps = 12/189 (6%) Query: 5 TSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPED- 63 + S ++ D ++Q+W+K FL +CPSG L +F + FF E+ Sbjct: 2 GQQFSWEEAEENGAVGAADAAQLQEWYKKFLEECPSGTLFMHEFKR----FFKVPDNEEA 57 Query: 64 --FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 + +F FD + + I F E++ L+ RGTLE KL W F++YD + +G I E+ Sbjct: 58 TQYVEAMFRAFDTNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQEL 117 Query: 122 LTIVASVYKMMGSMVTLNEDEA-----TPEMRVKKIFKLMDKNEDGYITLDEFREGSKVD 176 L IV S+YK+ + E E TPE V +IF L+D+N DG ++L+EF EG++ D Sbjct: 118 LDIVESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRD 177 Query: 177 PSIIGALNL 185 ++ L + Sbjct: 178 KWVMKMLQM 186 >2R2I-A nrPDB Length = 198 Score = 153 bits (387), Expect = 4e-38, Method: Composition-based stats. Identities = 50/170 (29%), Positives = 85/170 (50%), Gaps = 5/170 (2%) Query: 15 CLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDK 74 K E QW+K F+ +CPSGQL +F + + S + +F FD Sbjct: 4 DSKAVEELSATECHQWYKKFMTECPSGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDF 63 Query: 75 DNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 + +G+I F E++ LS +G +++KL W F+LYD++ +G I E+L I+ ++ Sbjct: 64 NKDGYIDFMEYVAALSLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAI-----R 118 Query: 135 MVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALN 184 + + T E +F +D N DG ++L+EF EG + D ++ L Sbjct: 119 AINRCNEAMTAEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILT 168 >2NA0-A nrPDB Length = 205 Score = 149 bits (376), Expect = 6e-37, Method: Composition-based stats. Identities = 51/164 (31%), Positives = 85/164 (51%), Gaps = 4/164 (2%) Query: 21 YFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFI 80 E QW+K F+ +CPSGQL +F + + + +F FD + +G+I Sbjct: 12 ELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPWASQYVEQMFETFDFNKDGYI 71 Query: 81 HFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNE 140 F E+ LS +G +E+KL W F+LYD++ +G I DE+LTI+ ++ + ++ Sbjct: 72 DFMEYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRAINPC----SD 127 Query: 141 DEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALN 184 T E +F +D N DG ++L+EF EG + D ++ L Sbjct: 128 STMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLT 171 >2GGZ-A nrPDB Length = 211 Score = 137 bits (345), Expect = 3e-33, Method: Composition-based stats. Identities = 42/157 (26%), Positives = 76/157 (48%), Gaps = 6/157 (3%) Query: 25 REIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE 84 +E W++ F+ + PSG +F + + ++ FD + +GF+ F E Sbjct: 19 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 78 Query: 85 FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEAT 144 FI ++ + +E+KL W F+LYD + +G I +E+L + +V + G + Sbjct: 79 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQT------LS 132 Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIG 181 PE + +F +D N DG +TL+EF G D ++ Sbjct: 133 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLE 169 >2ZFD-A nrPDB Length = 226 Score = 134 bits (336), Expect = 3e-32, Method: Composition-based stats. Identities = 49/180 (27%), Positives = 82/180 (45%), Gaps = 13/180 (7%) Query: 12 DLTCLKQSTYFDRREIQQWHKGFLRDCP----SGQLAREDFVKIYKQFFPFGSPED-FAN 66 D L + T F EI+ ++ F + G + +E+F F E FA+ Sbjct: 32 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ---LALFKTNKKESLFAD 88 Query: 67 HLFTVFDKDNNGFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 +F +FD +NG + FEEF LS +++K+ ++F+LYDL G+I E+ +V Sbjct: 89 RVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 Query: 126 ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNL 185 + G +N + E + K F+ D DG I +E+R PS++ + L Sbjct: 149 VATLAESG----MNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 >1UHN-A nrPDB Length = 189 Score = 129 bits (324), Expect = 7e-31, Method: Composition-based stats. Identities = 49/180 (27%), Positives = 82/180 (45%), Gaps = 13/180 (7%) Query: 12 DLTCLKQSTYFDRREIQQWHKGFLRDCP----SGQLAREDFVKIYKQFFPFGSPED-FAN 66 D L + T F EI+ ++ F + G + +E+F F E FA+ Sbjct: 1 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ---LALFKTNKKESLFAD 57 Query: 67 HLFTVFDKDNNGFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 +F +FD +NG + FEEF LS +++K+ ++F+LYDL G+I E+ +V Sbjct: 58 RVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 117 Query: 126 ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNL 185 + G +N + E + K F+ D DG I +E+R PS++ + L Sbjct: 118 VATLAESG----MNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 173 >4IL1-A nrPDB Length = 823 Score = 129 bits (324), Expect = 9e-31, Method: Composition-based stats. Identities = 52/178 (29%), Positives = 90/178 (50%), Gaps = 22/178 (12%) Query: 16 LKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 L+ ++FD EI++ K F L SG L+ E+F+ P + +FD Sbjct: 166 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-----LPELQQNPLVQRVIDIFD 220 Query: 74 KDNNGFIHFEEFITVLSTTS-RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 D NG + F+EFI +S S +G E+KL +AF +YD++ DGYI+ E+ ++++ Sbjct: 221 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL-------FQVL 273 Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI 190 MV N + + V K DK+ DG I+ +EF +++G L+++ ++ Sbjct: 274 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF-------CAVVGGLDIHKKMV 324 Score = 113 bits (282), Expect = 6e-26, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 11 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 70 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 71 TMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 110 Score = 112 bits (279), Expect = 1e-25, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D N Sbjct: 4 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 61 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 62 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT---------- 111 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG + +EF + Sbjct: 112 --NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 105 bits (263), Expect = 9e-24, Method: Composition-based stats. Identities = 36/177 (20%), Positives = 74/177 (41%), Gaps = 13/177 (7%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D +G + +F+ + + E+ F VFDKD NG+I Sbjct: 45 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 103 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNED- 141 E V++ +E++ D++ DG + ++E + ++ + G NE Sbjct: 104 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEAS 163 Query: 142 ---------EATPEMRVKKIFKLMDKNEDGYITLDEFREG--SKVDPSIIGALNLYD 187 +A R+ K FK +D + G ++++EF + +P + ++++D Sbjct: 164 YPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFD 220 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 37/97 (38%), Gaps = 19/97 (19%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 11 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 58 Query: 159 NEDGYITLDEFREGSKV-------DPSIIGALNLYDG 188 + +G I EF + I A ++D Sbjct: 59 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDK 95 >1V1G-A nrPDB Length = 222 Score = 126 bits (316), Expect = 7e-30, Method: Composition-based stats. Identities = 53/191 (27%), Positives = 87/191 (45%), Gaps = 14/191 (7%) Query: 3 AKTSKLSK---DDLTCLKQSTYFDRREIQQWHKGFLRDCPS----GQLAREDFVKIYKQF 55 K + + +D L T F E++ ++ F + S G + +E+F F Sbjct: 9 KKKNAMRPPGYEDPELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQ--LALF 66 Query: 56 FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDG 114 FA+ +F VFD NG I F EF+ L + EK+ +AF+LYDL G Sbjct: 67 RNRNRRNLFADRIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTG 126 Query: 115 YITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 +I +E+ +V ++ L E E+ V K F D+ DG I +DE+++ Sbjct: 127 FIEREELKEMVVALLHES----ELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVS 182 Query: 175 VDPSIIGALNL 185 ++PS+I + L Sbjct: 183 LNPSLIKNMTL 193 >3HZT-A nrPDB Length = 467 Score = 122 bits (305), Expect = 1e-28, Method: Composition-based stats. Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 25/173 (14%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPF----------GSPEDFAN 66 K +T + +E+ Q + L + GQL R++ ++ Y++ + E + Sbjct: 306 KLTTLEETKELTQIFRQ-LDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVD 364 Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 H+ D D NG+I + EF+TV E+L AF+ +D + G IT +E+ + Sbjct: 365 HILQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFG 424 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSI 179 VT +DE + + + DKN DG + +EF E + + Sbjct: 425 ---------VTEVDDETWHQ-----VLQECDKNNDGEVDFEEFVEMMQKICDV 463 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 35/83 (42%), Gaps = 1/83 (1%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 ++L+ F D N DG + E++ + + G V + D + E V I + +D Sbjct: 314 KELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTV-SDLDSSQIEAEVDHILQSVDF 372 Query: 159 NEDGYITLDEFREGSKVDPSIIG 181 + +GYI EF ++ Sbjct: 373 DRNGYIEYSEFVTVCMDKQLLLS 395 >5YPX-A nrPDB Length = 223 Score = 115 bits (289), Expect = 8e-27, Method: Composition-based stats. Identities = 48/184 (26%), Positives = 90/184 (48%), Gaps = 9/184 (4%) Query: 1 MGAKTSKLSKDD--LTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPF 58 M K KL+++ +C K T + + +K L ++ R F I Q F Sbjct: 21 MSKKNQKLAEELYKTSCQKHFTKTEVESLIICYKNLLEGL---KMDRNLFRDILHQKFNM 77 Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 + + + +F FDKD++ +I E++ LS RGTL+EK+ + F ++DLN DGYI+ Sbjct: 78 -TEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLDEKMEYTFTVFDLNGDGYISR 136 Query: 119 DEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPS 178 +EM ++ + T + + + V+ K MD + D ++ +F++ ++P Sbjct: 137 EEMFQMLKTCL---VKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKKDFKDAVLIEPL 193 Query: 179 IIGA 182 ++ A Sbjct: 194 LLEA 197 >4ORC-B nrPDB Length = 170 Score = 115 bits (288), Expect = 1e-26, Method: Composition-based stats. Identities = 52/178 (29%), Positives = 90/178 (50%), Gaps = 22/178 (12%) Query: 16 LKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 L+ ++FD EI++ K F L SG L+ E+F+ P + +FD Sbjct: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-----LPELQQNPLVQRVIDIFD 63 Query: 74 KDNNGFIHFEEFITVLSTTS-RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 D NG + F+EFI +S S +G E+KL +AF +YD++ DGYI+ E+ ++++ Sbjct: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL-------FQVL 116 Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI 190 MV N + + V K DK+ DG I+ +EF +++G L+++ ++ Sbjct: 117 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF-------CAVVGGLDIHKKMV 167 >4OY4-A nrPDB Length = 415 Score = 113 bits (284), Expect = 4e-26, Method: Composition-based stats. Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + DG I F E L Sbjct: 18 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFL 77 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 78 TMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 117 Score = 112 bits (280), Expect = 1e-25, Method: Composition-based stats. Identities = 33/157 (21%), Positives = 67/157 (42%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D + Sbjct: 11 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGD 68 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 69 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT---------- 118 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG + +EF + Sbjct: 119 --NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 87.8 bits (216), Expect = 2e-18, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 46/114 (40%), Gaps = 1/114 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D G + +F+ + + E+ F VFDKD NG+I Sbjct: 52 TEAELQDMINEVDAD-GDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 110 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 E V++ +E++ D++ DG + ++E + ++ + + V Sbjct: 111 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKLECEKMYV 164 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 37/97 (38%), Gaps = 19/97 (19%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 18 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 65 Query: 159 NEDGYITLDEFREGSKV-------DPSIIGALNLYDG 188 + DG I EF + I A ++D Sbjct: 66 DGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDK 102 >3U0K-A nrPDB Length = 442 Score = 113 bits (283), Expect = 4e-26, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + DG I F E L Sbjct: 304 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFL 363 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 ++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 364 IMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 403 Score = 112 bits (280), Expect = 1e-25, Method: Composition-based stats. Identities = 32/157 (20%), Positives = 66/157 (42%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D + Sbjct: 297 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGD 354 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+ +++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 355 GTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT---------- 404 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG + +EF + Sbjct: 405 --NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 439 Score = 87.0 bits (214), Expect = 4e-18, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 44/106 (41%), Gaps = 1/106 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D G + +F+ + + E+ F VFDKD NG+I Sbjct: 338 TEAELQDMINEVDAD-GDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 396 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 E V++ +E++ D++ DG + ++E + ++ + Sbjct: 397 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 442 Score = 55.4 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 37/97 (38%), Gaps = 19/97 (19%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 304 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 351 Query: 159 NEDGYITLDEFREGSKV-------DPSIIGALNLYDG 188 + DG I EF + I A ++D Sbjct: 352 DGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDK 388 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 19/46 (41%), Gaps = 2/46 (4%) Query: 126 ASVYKMMGSMVTLNEDEATPEMRV--KKIFKLMDKNEDGYITLDEF 169 +V + D+ T E K+ F L DK+ DG IT E Sbjct: 281 GAVMQKKTKGWEPTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKEL 326 >5JN2-A nrPDB Length = 525 Score = 112 bits (280), Expect = 1e-25, Method: Composition-based stats. Identities = 37/169 (21%), Positives = 64/169 (37%), Gaps = 25/169 (14%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP----------EDFAN 66 K ++ + +E+ + GQL R + ++ YK+ E + Sbjct: 368 KLTSQDETKELTAIFHK-MDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVD 426 Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NG+I + EF+TV E+L AF ++D ++ G I+ E+ TI Sbjct: 427 QVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFG 486 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 K + +DKN DG + DEF++ Sbjct: 487 V--------------SDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLK 521 >3EK4-A nrPDB Length = 451 Score = 111 bits (278), Expect = 2e-25, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 313 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 372 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 373 TMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 412 Score = 110 bits (274), Expect = 4e-25, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D N Sbjct: 306 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 363 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 364 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT---------- 413 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG + +EF + Sbjct: 414 --NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 448 Score = 85.9 bits (211), Expect = 9e-18, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 45/106 (42%), Gaps = 1/106 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D +G + +F+ + + E+ F VFDKD NG+I Sbjct: 347 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 405 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 E V++ +E++ D++ DG + ++E + ++ + Sbjct: 406 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 451 Score = 57.0 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 45/124 (36%), Gaps = 27/124 (21%) Query: 80 IHFEEFITVLSTTSRGTLEEKL--------SWAFELYDLNHDGYITFDEMLTIVASVYKM 131 I F+E +L ++L AF L+D + DG IT E+ T++ S+ + Sbjct: 286 IDFKEDGNILGHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ- 344 Query: 132 MGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV-------DPSIIGALN 184 E ++ + +D + +G I EF + I A Sbjct: 345 -----------NPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFR 393 Query: 185 LYDG 188 ++D Sbjct: 394 VFDK 397 >3KHE-A nrPDB Length = 191 Score = 109 bits (273), Expect = 7e-25, Method: Composition-based stats. Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 25/173 (14%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPF----------GSPEDFAN 66 K +T + +E+ Q + L + GQL R++ ++ Y++ + E + Sbjct: 32 KLTTLEETKELTQIFRQ-LDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVD 90 Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 H+ D D NG+I + EF+TV E+L AF+ +D + G IT +E+ + Sbjct: 91 HILQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFG 150 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSI 179 VT +DE + + + DKN DG + +EF E + + Sbjct: 151 ---------VTEVDDETWHQ-----VLQECDKNNDGEVDFEEFVEMMQKICDV 189 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 35/83 (42%), Gaps = 1/83 (1%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 ++L+ F D N DG + E++ + + G V + D + E V I + +D Sbjct: 40 KELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTV-SDLDSSQIEAEVDHILQSVDF 98 Query: 159 NEDGYITLDEFREGSKVDPSIIG 181 + +GYI EF ++ Sbjct: 99 DRNGYIEYSEFVTVCMDKQLLLS 121 >4YZB-A nrPDB Length = 491 Score = 109 bits (272), Expect = 9e-25, Method: Composition-based stats. Identities = 36/169 (21%), Positives = 67/169 (39%), Gaps = 25/169 (14%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFP----------FGSPEDFAN 66 K +T + E+ + + + GQL +++ ++ Y + + E Sbjct: 331 KLTTNEETVELNKIFQR-MDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVE 389 Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + D D NGFI + EF+TV ++L AF ++D + G I+ E+ TI Sbjct: 390 QVLDAVDFDKNGFIEYSEFVTVAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIFG 449 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E E +++ +D+N DG + +EFR+ Sbjct: 450 -------------VSEVDSE-TWRRVLAEVDRNNDGEVDFEEFRQMLLK 484 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Query: 85 FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEAT 144 + + S + +L+ F+ D N DG + E++ + K+ G V D++ Sbjct: 325 LLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDV-SALDQSA 383 Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNL 185 E V+++ +D +++G+I EF + +++ L Sbjct: 384 IEFEVEQVLDAVDFDKNGFIEYSEFVTVAMDRKTLLSRQRL 424 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 + A+ MGS +T NE+ + KIF+ MDKN DG + E EG Sbjct: 318 QKLAAAALLYMGSKLTTNEETV----ELNKIFQRMDKNGDGQLDKQELMEG 364 >5B8I-B nrPDB Length = 171 Score = 108 bits (271), Expect = 1e-24, Method: Composition-based stats. Identities = 47/169 (27%), Positives = 82/169 (48%), Gaps = 15/169 (8%) Query: 8 LSKDDLTCLKQSTYFDRREIQQWHKGFLRDC--PSGQLAREDFVKIYKQFFPFGSPEDFA 65 +S L + + FD E+ + K F++ SG + R++F+ P S + Sbjct: 1 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLS-----LPQVSSNPLS 55 Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTS-RGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 + +FD+D G + F+EF++ LS S +G EEKL +AF++YD++ DG+I+ E+ + Sbjct: 56 TRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIV 115 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 + MV N + + V K D + DG I+ +EF Sbjct: 116 LK-------MMVGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMV 157 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 26/77 (33%), Gaps = 16/77 (20%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 ++L F D + G I DE L++ + + ++ + D+ Sbjct: 21 DRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLST----------------RMIAIFDE 64 Query: 159 NEDGYITLDEFREGSKV 175 + G + EF G Sbjct: 65 DGGGDVDFQEFVSGLSA 81 >5UKG-A nrPDB Length = 419 Score = 108 bits (270), Expect = 1e-24, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 64/157 (40%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D + Sbjct: 274 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGD 331 Query: 78 GFIHFEEFITVL-STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G F EF+T++ S EE++ AF ++D + +GYI E+ ++ Sbjct: 332 GTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMT---------- 381 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 + E + V ++ ++ D + DG + +EF + Sbjct: 382 --DLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 416 Score = 107 bits (266), Expect = 4e-24, Method: Composition-based stats. Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 25/137 (18%) Query: 37 DCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT 96 + +GQL E F++FDKD +G I +E TV+ + + Sbjct: 269 EASNGQLTEEQI--------------AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNP 314 Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 E +L D + DG F E LT++A E +++ F++ Sbjct: 315 TEAELQDMINEVDADGDGTFDFPEFLTMMARKMSYR-----------VTEEEIREAFRVF 363 Query: 157 DKNEDGYITLDEFREGS 173 DK+ +GYI E R Sbjct: 364 DKDGNGYIGAAELRHVM 380 Score = 82.0 bits (201), Expect = 1e-16, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 45/106 (42%), Gaps = 1/106 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D G +F+ + + + E+ F VFDKD NG+I Sbjct: 315 TEAELQDMINEVDAD-GDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGA 373 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 E V++ +E++ + D++ DG + ++E + ++ + Sbjct: 374 AELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTAK 419 Score = 53.9 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 36/97 (37%), Gaps = 19/97 (19%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 281 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 328 Query: 159 NEDGYITLDEFREGSKV-------DPSIIGALNLYDG 188 + DG EF + I A ++D Sbjct: 329 DGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDK 365 Score = 30.4 bits (67), Expect = 0.53, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 17/40 (42%) Query: 130 KMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 K +G + + K+ F L DK+ DG IT E Sbjct: 264 KTLGWEASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKEL 303 >4I2Y-A nrPDB Length = 421 Score = 107 bits (268), Expect = 2e-24, Method: Composition-based stats. Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + DG F E L Sbjct: 283 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFL 342 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A ++ E +++ F++ DK+ +GYI E R Sbjct: 343 TMMARKM-----------NDTDSEEEIREAFRVFDKDGNGYIGAAELRHVM 382 Score = 104 bits (259), Expect = 2e-23, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 65/157 (41%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D + Sbjct: 276 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGD 333 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G F EF+T+++ T EE++ AF ++D + +GYI E+ ++ Sbjct: 334 GTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMT---------- 383 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 + E + V ++ ++ D + DG + +EF + Sbjct: 384 --DLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 418 Score = 83.2 bits (204), Expect = 6e-17, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 44/106 (41%), Gaps = 1/106 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D G +F+ + + E+ F VFDKD NG+I Sbjct: 317 TEAELQDMINEVDAD-GDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGA 375 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 E V++ +E++ + D++ DG + ++E + ++ + Sbjct: 376 AELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTAK 421 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 36/97 (37%), Gaps = 19/97 (19%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 283 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 330 Query: 159 NEDGYITLDEFREGSKV-------DPSIIGALNLYDG 188 + DG EF + I A ++D Sbjct: 331 DGDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDK 367 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 18/40 (45%) Query: 130 KMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 K MG T ++ K+ F L DK+ DG IT E Sbjct: 266 KTMGWEATRDQLTEEQIAEFKEAFSLFDKDGDGTITTKEL 305 >2LM5-A nrPDB Length = 214 Score = 107 bits (268), Expect = 3e-24, Method: Composition-based stats. Identities = 45/194 (23%), Positives = 79/194 (40%), Gaps = 14/194 (7%) Query: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQF----- 55 MG S+LSK+ L + T+ ++EI H+ F P Q + E ++ F Sbjct: 24 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 83 Query: 56 FPFGSPEDFANHLFTVFD----KDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLN 111 P F + VF KD+ F F + ++V S T T + K +AF ++D + Sbjct: 84 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDT--ATPDIKSHYAFRIFDFD 141 Query: 112 HDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 DG + +++ +V + G + + + I + D + DG I L EF+ Sbjct: 142 DDGTLNREDLSRLV---NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 198 Query: 172 GSKVDPSIIGALNL 185 P + + Sbjct: 199 VISRSPDFASSFKI 212 >2E6W-A nrPDB Length = 100 Score = 107 bits (267), Expect = 3e-24, Method: Composition-based stats. Identities = 43/96 (44%), Positives = 64/96 (66%) Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 GT+ EKL WAF LYD+N DGYIT +EML I+ S+Y MMG E P V++ F+ Sbjct: 5 GTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFE 64 Query: 155 LMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI 190 MD+N+DG +T++EF E + D +I+ ++ L++ +I Sbjct: 65 KMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI 100 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 35/90 (38%), Gaps = 12/90 (13%) Query: 58 FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLST------------TSRGTLEEKLSWAF 105 G+ + F ++D + +G+I EE + ++ + E + F Sbjct: 4 MGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFF 63 Query: 106 ELYDLNHDGYITFDEMLTIVASVYKMMGSM 135 E D N DG +T +E L +M SM Sbjct: 64 EKMDRNQDGVVTIEEFLEACQKDENIMSSM 93 Score = 33.9 bits (76), Expect = 0.047, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 25/78 (32%), Gaps = 11/78 (14%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYK-----------QFFPFGSPEDFANHLFTV 71 E +W G + +E+ + I K +P + F Sbjct: 6 TVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEK 65 Query: 72 FDKDNNGFIHFEEFITVL 89 D++ +G + EEF+ Sbjct: 66 MDRNQDGVVTIEEFLEAC 83 >3LIJ-A nrPDB Length = 494 Score = 107 bits (267), Expect = 3e-24, Method: Composition-based stats. Identities = 35/169 (20%), Positives = 69/169 (40%), Gaps = 22/169 (13%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQF-------FPFGSPEDFANHLF 69 K ++ + +E+ + + GQL R++ + Y + F E + + Sbjct: 338 KLTSQEETKELTDIFRH-IDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAIL 396 Query: 70 TVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 D D NG+I + EF+TV ++KL AF+ +D + +G I+ DE+ ++ Sbjct: 397 GAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFG--- 453 Query: 130 KMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPS 178 + K++ +D N DG + +EF + + S Sbjct: 454 -----------LDHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLCS 491 Score = 49.7 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 35/97 (36%), Gaps = 4/97 (4%) Query: 85 FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEAT 144 + + S + ++L+ F D N DG + E++ Y + D Sbjct: 332 LLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELID----GYSKLSGEEVAVFDLPQ 387 Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIG 181 E V I D + +GYI EF + S++ Sbjct: 388 IESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLS 424 >3Q5I-A nrPDB Length = 504 Score = 107 bits (267), Expect = 3e-24, Method: Composition-based stats. Identities = 40/166 (24%), Positives = 67/166 (40%), Gaps = 22/166 (13%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP-------EDFANHLF 69 K +T +R+E+ K L GQL +++ ++ Y F + E+ +++ Sbjct: 347 KLTTLEERKELTDIFKK-LDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNIL 405 Query: 70 TVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 D D NG+I + EFI+V EE+L AF L+D + G IT +E+ + Sbjct: 406 KEVDFDKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLFG--- 462 Query: 130 KMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 + E + D+N+D I DEF Sbjct: 463 -----------LTSISEKTWNDVLGEADQNKDNMIDFDEFVSMMHK 497 Score = 33.1 bits (74), Expect = 0.071, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 15/37 (40%) Query: 136 VTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 + + IFK +DKN DG + E EG Sbjct: 344 IGSKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEG 380 >4RGJ-A nrPDB Length = 520 Score = 106 bits (264), Expect = 6e-24, Method: Composition-based stats. Identities = 43/188 (22%), Positives = 74/188 (39%), Gaps = 27/188 (14%) Query: 3 AKTSKLSKDDLTCL--KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFP--- 57 T KL++ L + K +T + +E+ + K + GQL R + + YK+ Sbjct: 347 QSTQKLAQAALLYMGSKLTTIDETKELTKIFKK-MDKNGDGQLDRNELIIGYKELLKLKG 405 Query: 58 -------FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDL 110 + E + + D D NG+I + EF+TV E+L AF+L+D Sbjct: 406 EDTSDLDNAAIEYEVDQILNSIDLDQNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDK 465 Query: 111 NHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + G I+ +E+ + K + K +D+N DG I EFR Sbjct: 466 DGSGKISANELAQLFG--------------LSDVSSECWKTVLKEVDQNNDGEIDFKEFR 511 Query: 171 EGSKVDPS 178 + + Sbjct: 512 DMLVKLCN 519 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 7/96 (7%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 ++L+ F+ D N DG + +E++ + K+ G T + D A E V +I +D Sbjct: 371 KELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKG-EDTSDLDNAAIEYEVDQILNSIDL 429 Query: 159 NEDGYITLDEF------REGSKVDPSIIGALNLYDG 188 +++GYI EF R+ + A L+D Sbjct: 430 DQNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDK 465 >3NCG-A nrPDB Length = 486 Score = 103 bits (256), Expect = 6e-23, Method: Composition-based stats. Identities = 35/171 (20%), Positives = 71/171 (41%), Gaps = 26/171 (15%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPF-------------GSPED 63 K +T + +++ + + L G L R++ V+ Y +F + ED Sbjct: 323 KLTTLDETKQLTEIFRK-LDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIED 381 Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 + L + D D +G I + EFI + E++ AF+++D + G I+ E+ Sbjct: 382 QIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKISTKELFK 441 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 + + D + ++ I + +D N+DG + +EF E + Sbjct: 442 LFSQA------------DSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQ 480 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 43/95 (45%), Gaps = 2/95 (2%) Query: 2 GAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP 61 G+ + + S+ + + ++ R +++ K F +D SG+++ ++ K++ Q Sbjct: 394 GSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKD-GSGKISTKELFKLFSQAD-SSIQ 451 Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT 96 + + D + +G + F EF+ +L R Sbjct: 452 MEELESIIEQVDNNKDGEVDFNEFVEMLQNFVRNE 486 >3WFN-B nrPDB Length = 182 Score = 101 bits (251), Expect = 2e-22, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 17 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 76 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 77 TMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 116 Score = 98.6 bits (244), Expect = 1e-21, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D N Sbjct: 10 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 67 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 68 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT---------- 117 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG + +EF + Sbjct: 118 --NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 152 Score = 79.3 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 47/114 (41%), Gaps = 1/114 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D +G + +F+ + + E+ F VFDKD NG+I Sbjct: 51 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 109 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 E V++ +E++ D++ DG + ++E + ++ + G V Sbjct: 110 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGEEV 163 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 17 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 64 Query: 159 NEDGYITLDEFREGSKV 175 + +G I EF Sbjct: 65 DGNGTIDFPEFLTMMAR 81 >2N6A-A nrPDB Length = 173 Score = 101 bits (251), Expect = 2e-22, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 12 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 71 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 72 TMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 111 Score = 97.8 bits (242), Expect = 2e-21, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 66/155 (42%), Gaps = 15/155 (9%) Query: 20 TYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGF 79 T E ++ F +D G + ++ + + + E + D D NG Sbjct: 7 TEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGNGT 64 Query: 80 IHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTL 138 I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 65 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT------------ 112 Query: 139 NEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG + +EF + Sbjct: 113 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 147 Score = 78.6 bits (192), Expect = 2e-15, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 46/112 (41%), Gaps = 1/112 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D +G + +F+ + + E+ F VFDKD NG+I Sbjct: 46 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 104 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 E V++ +E++ D++ DG + ++E + ++ GS Sbjct: 105 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTGASTAAGS 156 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 12 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 59 Query: 159 NEDGYITLDEFREGSKV 175 + +G I EF Sbjct: 60 DGNGTIDFPEFLTMMAR 76 >3L19-A nrPDB Length = 214 Score = 99.4 bits (246), Expect = 9e-22, Method: Composition-based stats. Identities = 35/169 (20%), Positives = 69/169 (40%), Gaps = 22/169 (13%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQF-------FPFGSPEDFANHLF 69 K ++ + +E+ + + GQL R++ + Y + F E + + Sbjct: 55 KLTSQEETKELTDIFRH-IDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAIL 113 Query: 70 TVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 D D NG+I + EF+TV ++KL AF+ +D + +G I+ DE+ ++ Sbjct: 114 GAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFG--- 170 Query: 130 KMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPS 178 + K++ +D N DG + +EF + + S Sbjct: 171 -----------LDHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLCS 208 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 35/97 (36%), Gaps = 4/97 (4%) Query: 85 FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEAT 144 + + S + ++L+ F D N DG + E++ Y + D Sbjct: 49 LLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELID----GYSKLSGEEVAVFDLPQ 104 Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIG 181 E V I D + +GYI EF + S++ Sbjct: 105 IESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLS 141 >6O20-F nrPDB Length = 169 Score = 98.2 bits (243), Expect = 2e-21, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 31 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 90 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 91 TMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 130 Score = 95.1 bits (235), Expect = 1e-20, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D N Sbjct: 24 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 81 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 82 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT---------- 131 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG + +EF + Sbjct: 132 --NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 166 Score = 75.9 bits (185), Expect = 9e-15, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 45/106 (42%), Gaps = 1/106 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D +G + +F+ + + E+ F VFDKD NG+I Sbjct: 65 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 123 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 E V++ +E++ D++ DG + ++E + ++ + Sbjct: 124 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 169 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 31 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 78 Query: 159 NEDGYITLDEFREGSKV 175 + +G I EF Sbjct: 79 DGNGTIDFPEFLTMMAR 95 >1DGU-A nrPDB Length = 183 Score = 97.8 bits (242), Expect = 2e-21, Method: Composition-based stats. Identities = 41/186 (22%), Positives = 74/186 (39%), Gaps = 14/186 (7%) Query: 9 SKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQF-----FPFGSPED 63 SK+ L + T+ ++EI H+ F P Q + E ++ F P Sbjct: 1 SKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANP 60 Query: 64 FANHLFTVFD----KDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 F + VF KD+ F F + ++V S T T + K +AF ++D + DG + + Sbjct: 61 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDT--ATPDIKSHYAFRIFDFDDDGTLNRE 118 Query: 120 EMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSI 179 ++ +V + G + + + I + D + DG I L EF+ P Sbjct: 119 DLSRLV---NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDF 175 Query: 180 IGALNL 185 + + Sbjct: 176 ASSFKI 181 >2F2P-A nrPDB Length = 179 Score = 97.8 bits (242), Expect = 2e-21, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 11 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 70 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 71 TMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 110 Score = 95.1 bits (235), Expect = 2e-20, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D N Sbjct: 4 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 61 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 62 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT---------- 111 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG + +EF + Sbjct: 112 --NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 75.9 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 45/106 (42%), Gaps = 1/106 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D +G + +F+ + + E+ F VFDKD NG+I Sbjct: 45 TEAELQDMINEVDAD-GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 103 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 E V++ +E++ D++ DG + ++E + ++ + Sbjct: 104 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 11 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 58 Query: 159 NEDGYITLDEFREGSKV 175 + +G I EF Sbjct: 59 DGNGTIDFPEFLTMMAR 75 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 12/84 (14%), Positives = 33/84 (39%), Gaps = 2/84 (2%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 EI++ + F +D +G ++ + + ++ + + D D +G +++ Sbjct: 82 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLG-EKLTDEEVDEMIREADIDGDGQVNY 139 Query: 83 EEFITVLSTTSRGTLEEKLSWAFE 106 EEF+ +++ G Sbjct: 140 EEFVQMMTAKGGGGGAAARKEVIR 163 >1DTL-A nrPDB Length = 161 Score = 97.4 bits (241), Expect = 3e-21, Method: Composition-based stats. Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 17/165 (10%) Query: 14 TCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 ++Q T + E + F+ G ++ ++ K+ + +PE+ + D Sbjct: 7 AAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMI-DEVD 65 Query: 74 KDNNGFIHFEEFITVL----STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 +D +G + F+EF+ ++ S+G EE+LS F ++D N DGYI +E+ ++ + Sbjct: 66 EDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATG 125 Query: 130 KMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 E E ++++ K DKN DG I DEF E K Sbjct: 126 ------------ETITEDDIEELMKDGDKNNDGRIDYDEFLEFMK 158 Score = 67.4 bits (163), Expect = 4e-12, Method: Composition-based stats. Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPF---GSPEDFANHLFTVFDKDNNGFIHFEEFITVLST 91 + + SG + ++F+ + + G E+ + LF +FDK+ +G+I EE +L Sbjct: 64 VDEDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQA 123 Query: 92 TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 T E+ + + D N+DG I +DE L + V Sbjct: 124 TGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGV 160 Score = 65.8 bits (159), Expect = 9e-12, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 8/99 (8%) Query: 77 NGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 +G I +E V+ + E+L + D + G + FDE L ++ K Sbjct: 33 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMK------ 86 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 ++ + E + +F++ DKN DGYI L+E + + Sbjct: 87 --DDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQA 123 >4E53-A nrPDB Length = 185 Score = 96.3 bits (238), Expect = 8e-21, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 18 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 77 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 78 TMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 117 Score = 93.2 bits (230), Expect = 7e-20, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D N Sbjct: 11 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 68 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 69 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT---------- 118 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG + +EF + Sbjct: 119 --NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 18 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 65 Query: 159 NEDGYITLDEFREGSKV 175 + +G I EF Sbjct: 66 DGNGTIDFPEFLTMMAR 82 >6HCS-A nrPDB Length = 167 Score = 95.5 bits (236), Expect = 1e-20, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 11 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 70 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 71 TMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHFM 110 Score = 92.0 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 37/172 (21%), Positives = 70/172 (40%), Gaps = 15/172 (8%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D N Sbjct: 4 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 61 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ + Sbjct: 62 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMT---------- 111 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDG 188 N E + V ++ + D + DG + +EF + G L+ G Sbjct: 112 --NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKLEGTGLEVLFQG 161 >2E30-A nrPDB Length = 195 Score = 92.0 bits (227), Expect = 1e-19, Method: Composition-based stats. Identities = 50/199 (25%), Positives = 84/199 (42%), Gaps = 41/199 (20%) Query: 1 MGAKTSKLSK-DDLTCLKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKI------ 51 MG++ S L + ++L +K+ T F +I + + F L +G L+REDF +I Sbjct: 1 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAIN 60 Query: 52 ------YKQFFPFGSPEDFAN---------HLFTVFDKDNNGFIHFEEFITVLSTTSRGT 96 FFP G ED N H + D + + ++ E + S Sbjct: 61 PLGDRIINAFFPEG--EDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSN----- 113 Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 KL +AF LYDL+ D I+ DE+L ++ MV +N + + + Sbjct: 114 ---KLHFAFRLYDLDKDEKISRDELLQVLR-------MMVGVNISDEQLGSIADRTIQEA 163 Query: 157 DKNEDGYITLDEFREGSKV 175 D++ D I+ EF + + Sbjct: 164 DQDGDSAISFTEFVKVLEK 182 >1GGZ-A nrPDB Length = 148 Score = 92.0 bits (227), Expect = 1e-19, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 49/113 (43%), Gaps = 11/113 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I E TV+ + + E +L D + +G + F E L Sbjct: 10 TEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFL 69 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 ++A K + E +++ F++ DK+ +G+++ E R Sbjct: 70 GMMARKMK-----------DTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTR 111 Score = 86.3 bits (212), Expect = 8e-18, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 66/155 (42%), Gaps = 15/155 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + + + + + E + + D+D N Sbjct: 3 QLTEEQVTEFKEAFSLFDKD-GDGCITTRELGTVMRSLGQNPT-EAELRDMMSEIDRDGN 60 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G + F EF+ +++ + T EE++ AF ++D + +G+++ E+ ++ + Sbjct: 61 GTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLG------- 113 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 E + V ++ + D + DG + +EF Sbjct: 114 -----EKLSDEEVDEMIRAADTDGDGQVNYEEFVR 143 Score = 67.0 bits (162), Expect = 4e-12, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 40/89 (44%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 +G + +F+ + + E+ F VFDKD NGF+ E V++ +E Sbjct: 60 NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE 119 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASV 128 ++ D + DG + ++E + ++ S Sbjct: 120 EVDEMIRAADTDGDGQVNYEEFVRVLVSK 148 >5I0I-E nrPDB Length = 145 Score = 92.0 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++ DKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 9 AEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 68 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 T++A K + E +++ F++ DK+ +GYI+ E R Sbjct: 69 TMMARKMK-----------DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 108 Score = 88.2 bits (217), Expect = 2e-18, Method: Composition-based stats. Identities = 33/157 (21%), Positives = 66/157 (42%), Gaps = 15/157 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ +D G + ++ + + + E + D D N Sbjct: 2 QLTEEQIAEFKEAFSLADKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 59 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ ++ Sbjct: 60 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT---------- 109 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG + +EF + Sbjct: 110 --NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 144 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 30/77 (38%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 9 AEFKEAFSLADKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 56 Query: 159 NEDGYITLDEFREGSKV 175 + +G I EF Sbjct: 57 DGNGTIDFPEFLTMMAR 73 >5A2H-A nrPDB Length = 149 Score = 89.7 bits (221), Expect = 6e-19, Method: Composition-based stats. Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 11/115 (9%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 F++FDKD +G I +E TV+ + + E +L D + +G I F Sbjct: 7 DDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDF 66 Query: 119 DEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 E L ++A K + E +K+ F++ DK+++G+I+ E R Sbjct: 67 PEFLNLMARKMK-----------DTDSEEELKEAFRVFDKDQNGFISAAELRHVM 110 Score = 85.5 bits (210), Expect = 1e-17, Method: Composition-based stats. Identities = 34/159 (21%), Positives = 66/159 (41%), Gaps = 15/159 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D N Sbjct: 4 QLTDDQISEFKEAFSLFDKD-GDGCITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 61 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F EF+ +++ + T EE+L AF ++D + +G+I+ E+ ++ Sbjct: 62 GTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMT---------- 111 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 N E + V ++ + D + DG I +EF + Sbjct: 112 --NLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMMA 148 Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 41/89 (46%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 +G + +F+ + + E+ F VFDKD NGFI E V++ +E Sbjct: 61 NGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDE 120 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASV 128 ++ D++ DG I ++E + ++ + Sbjct: 121 EVDEMIREADVDGDGQINYEEFVKVMMAK 149 >1CLM-A nrPDB Length = 148 Score = 89.3 bits (220), Expect = 9e-19, Method: Composition-based stats. Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 11/111 (9%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F +FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 10 AEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 69 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 +++A K E E + + FK+ D++ +G I+ E R Sbjct: 70 SLMARKMK-----------EQDSEEELIEAFKVFDRDGNGLISAAELRHVM 109 Score = 86.6 bits (213), Expect = 5e-18, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 65/158 (41%), Gaps = 15/158 (9%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDN 76 ++ T E ++ F +D G + ++ + + + E + D D Sbjct: 2 QELTEEQIAEFKEAFALFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADG 59 Query: 77 NGFIHFEEFITVL-STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSM 135 NG I F EF++++ EE+L AF+++D + +G I+ E+ ++ Sbjct: 60 NGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMT--------- 110 Query: 136 VTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 N E + V ++ + D + DG+I +EF Sbjct: 111 ---NLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMM 145 Score = 68.9 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 41/89 (46%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 +G + +F+ + + E+ F VFD+D NG I E V++ ++ Sbjct: 60 NGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDD 119 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASV 128 ++ D++ DG+I ++E + ++ S Sbjct: 120 EVDEMIREADIDGDGHINYEEFVRMMVSK 148 Score = 44.7 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 10 AEFKEAFALFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 57 Query: 159 NEDGYITLDEFREGSKV 175 + +G I EF Sbjct: 58 DGNGTIDFPEFLSLMAR 74 >2LHI-A nrPDB Length = 176 Score = 88.2 bits (217), Expect = 2e-18, Method: Composition-based stats. Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 11/108 (10%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F +FDKDNNG I E TV+ + E +++ D++ + I F E L Sbjct: 11 AEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFL 70 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 +++ K E + + FK+ DKN DG I+ E + Sbjct: 71 ALMSRQLKS-----------NDSEQELLEAFKVFDKNGDGLISAAELK 107 Score = 73.9 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 61/152 (40%), Gaps = 16/152 (10%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 T E ++ F +D +G ++ + + + E N L D D N Sbjct: 5 LTEEQIAEFKEAFALFDKDN-NGSISSSELATVMRSLG-LSPSEAEVNDLMNEIDVDGNH 62 Query: 79 FIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 I F EF+ ++S E++L AF+++D N DG I+ E+ ++ S+ Sbjct: 63 QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIG-------- 114 Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 E + V + + + + G I + +F Sbjct: 115 ----EKLTDAEVDDMLREVS-DGSGEINIQQF 141 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 34/94 (36%), Gaps = 1/94 (1%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + + Q+ +F+ + + E F VFDK+ +G I E VL++ Sbjct: 56 IDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGE 115 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 + ++ + G I + +++ Sbjct: 116 KLTDAEVDDMLREV-SDGSGEINIQQFAALLSKG 148 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 37/97 (38%), Gaps = 19/97 (19%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D +++G I+ E+ T++ S+ + E V + +D Sbjct: 11 AEFKEAFALFDKDNNGSISSSELATVMRSLGL------------SPSEAEVNDLMNEIDV 58 Query: 159 NEDGYITLDEFREGSKV-------DPSIIGALNLYDG 188 + + I EF + ++ A ++D Sbjct: 59 DGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDK 95 Score = 30.0 bits (66), Expect = 0.58, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 33/84 (39%), Gaps = 3/84 (3%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDN 76 + + +E+ + K F ++ G ++ + + + + + L V D Sbjct: 76 QLKSNDSEQELLEAFKVFDKN-GDGLISAAELKHVLTSIGEKLTDAEVDDMLREV--SDG 132 Query: 77 NGFIHFEEFITVLSTTSRGTLEEK 100 +G I+ ++F +LS S K Sbjct: 133 SGEINIQQFAALLSKGSSTGTRRK 156 >2AAO-A nrPDB Length = 166 Score = 87.8 bits (216), Expect = 2e-18, Method: Composition-based stats. Identities = 36/156 (23%), Positives = 65/156 (41%), Gaps = 17/156 (10%) Query: 22 FDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGF 79 EI + F + SGQ+ E+ K+ + + L D DN+G Sbjct: 21 LSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILD-LMQAADVDNSGT 79 Query: 80 IHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLN 139 I ++EFI ++ E+ L AF +D + GYIT DE+ Sbjct: 80 IDYKEFIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQAC-------------- 125 Query: 140 EDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E+ ++R++++ + +D++ DG I +EF + Sbjct: 126 EEFGVEDVRIEELMRDVDQDNDGRIDYNEFVAMMQK 161 Score = 27.3 bits (59), Expect = 4.1, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 23/52 (44%), Gaps = 3/52 (5%) Query: 127 SVYKMMGSMVTLNEDEATPEMRV---KKIFKLMDKNEDGYITLDEFREGSKV 175 S M E+ E + K++F ++D ++ G IT +E + G K Sbjct: 4 SAMNKFKKMALRVIAESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKR 55 >4JWQ-A nrPDB Length = 199 Score = 86.3 bits (212), Expect = 8e-18, Method: Composition-based stats. Identities = 42/160 (26%), Positives = 75/160 (46%), Gaps = 13/160 (8%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDN 76 +QS +D ++++ +L + G + + K + + L D D Sbjct: 50 QQSNDYDLQQLKTVF-LYLDEDGKGNITKNQLKKGLENSGLKLPQN--FDVLLDQIDSDG 106 Query: 77 NGFIHFEEFITVLSTTSRGTLEEKLSW-AFELYDLNHDGYITFDEMLTIVASVYKMMGSM 135 +G I + EF+ R L +KL + AF ++D+++DG IT E+ I+ + K GS+ Sbjct: 107 SGRIDYTEFLAA--ALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKK-GSI 163 Query: 136 VTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 + ++ VKK+ + +DKN DG I EF E K+ Sbjct: 164 TQKDVNQ------VKKMIQEVDKNNDGKIDFYEFCEMMKL 197 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 41/100 (41%), Gaps = 7/100 (7%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL-STTS 93 + SG++ +F+ + F VFD DN+G I E +L + Sbjct: 102 IDSDGSGRIDYTEFL--AAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNK 159 Query: 94 RGTLEEK----LSWAFELYDLNHDGYITFDEMLTIVASVY 129 +G++ +K + + D N+DG I F E ++ Y Sbjct: 160 KGSITQKDVNQVKKMIQEVDKNNDGKIDFYEFCEMMKLKY 199 Score = 31.2 bits (69), Expect = 0.30, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 24/85 (28%), Gaps = 13/85 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 ++L F D + G IT +++ L + +D Sbjct: 58 QQLKTVFLYLDEDGKGNITKNQLKK-------------GLENSGLKLPQNFDVLLDQIDS 104 Query: 159 NEDGYITLDEFREGSKVDPSIIGAL 183 + G I EF + + L Sbjct: 105 DGSGRIDYTEFLAAALDRKHLSKKL 129 >1TOP-A nrPDB Length = 162 Score = 85.1 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 37/172 (21%), Positives = 72/172 (41%), Gaps = 18/172 (10%) Query: 6 SKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFA 65 + ++ + E + F D G ++ ++ + + + E+ Sbjct: 1 ASMTDQQAEARAFLSEEMIAEFKAAFDMFDADGG-GDISTKELGTVMRMLGQNPTKEEL- 58 Query: 66 NHLFTVFDKDNNGFIHFEEFITVL----STTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 + + D+D +G I FEEF+ ++ ++G EE+L+ F ++D N DG+I +E+ Sbjct: 59 DAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEEL 118 Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 I+ + E E ++ + K DKN DG I DEF + Sbjct: 119 GEILRATG------------EHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMM 158 Score = 74.3 bits (181), Expect = 3e-14, Method: Composition-based stats. Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPF---GSPEDFANHLFTVFDKDNNGF 79 + E+ + + + SG + E+F+ + + G E+ + F +FDK+ +GF Sbjct: 54 TKEELDAIIEE-VDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGF 112 Query: 80 IHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 I EE +L T EE + + D N+DG I FDE L ++ V Sbjct: 113 IDIEELGEILRATGEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMMEGV 161 >2TN4-A nrPDB Length = 159 Score = 84.7 bits (208), Expect = 2e-17, Method: Composition-based stats. Identities = 37/167 (22%), Positives = 68/167 (40%), Gaps = 18/167 (10%) Query: 11 DDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFT 70 + E + F D G ++ ++ + + + E+ + + Sbjct: 3 QQAEARSYLSEEMIAEFKAAFDMFDADGG-GDISVKELGTVMRMLGQTPTKEEL-DAIIE 60 Query: 71 VFDKDNNGFIHFEEFITVL----STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 D+D +G I FEEF+ ++ ++G EE+L+ F ++D N DGYI +E+ I Sbjct: 61 EVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFR 120 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 + E + ++ + K DKN DG I DEF + Sbjct: 121 ASG------------EHVTDEEIESLMKDGDKNNDGRIDFDEFLKMM 155 Score = 71.2 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 51/109 (46%), Gaps = 4/109 (3%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPF---GSPEDFANHLFTVFDKDNNGF 79 + E+ + + + SG + E+F+ + + G E+ LF +FD++ +G+ Sbjct: 51 TKEELDAIIEE-VDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGY 109 Query: 80 IHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 I EE + + +E++ + D N+DG I FDE L ++ V Sbjct: 110 IDAEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMMEGV 158 >2L1W-A nrPDB Length = 149 Score = 84.7 bits (208), Expect = 2e-17, Method: Composition-based stats. Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 11/108 (10%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F +FDKD +G I EE TV+ + + EE+L D + +G I FDE L+++ Sbjct: 13 KEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLM 72 Query: 126 ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 A K + E +K+ FK+ DK+++GYI+ E R Sbjct: 73 AKKVK-----------DTDAEEELKEAFKVFDKDQNGYISASELRHVM 109 Score = 80.1 bits (196), Expect = 5e-16, Method: Composition-based stats. Identities = 33/156 (21%), Positives = 73/156 (46%), Gaps = 15/156 (9%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 + + ++ F +D G + E+ + + + E+ + + + D D NG Sbjct: 4 LSEEQIVDFKEAFGLFDKD-GDGCITVEELATVIRSLDQNPTEEELQDMI-SEVDADGNG 61 Query: 79 FIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 I F+EF+++++ + T EE+L AF+++D + +GYI+ E+ ++ Sbjct: 62 TIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVM------------ 109 Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 +N E + V+++ K D + DG + +EF + Sbjct: 110 INLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMM 145 Score = 69.7 bits (169), Expect = 8e-13, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 47/106 (44%), Gaps = 1/106 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q D +G + ++F+ + + E+ F VFDKD NG+I Sbjct: 44 TEEELQDMISEVDAD-GNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISA 102 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 E V+ +E++ + DL+ DG + ++E + ++ +V Sbjct: 103 SELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTV 148 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 32/74 (43%), Gaps = 12/74 (16%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 AF L+D + DG IT +E+ T++ + D+ E ++ + +D + + Sbjct: 13 KEAFGLFDKDGDGCITVEELATVI------------RSLDQNPTEEELQDMISEVDADGN 60 Query: 162 GYITLDEFREGSKV 175 G I DEF Sbjct: 61 GTIEFDEFLSLMAK 74 >3K21-A nrPDB Length = 191 Score = 84.3 bits (207), Expect = 3e-17, Method: Composition-based stats. Identities = 40/142 (28%), Positives = 67/142 (47%), Gaps = 12/142 (8%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 L + G + +E K ++ + L D D +G I + EFI R Sbjct: 61 LDEDGKGYITKEQLKKGLEKDGLKLPYN--FDLLLDQIDSDGSGKIDYTEFIAA--ALDR 116 Query: 95 GTLEEKLSW-AFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 L +KL + AF ++D+++DG IT E+ I+ + K G++ + + RVK++ Sbjct: 117 KQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKK-GNITQRDVN------RVKRMI 169 Query: 154 KLMDKNEDGYITLDEFREGSKV 175 + +DKN DG I EF E K+ Sbjct: 170 RDVDKNNDGKIDFHEFSEMMKL 191 Score = 36.6 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 28/85 (32%), Gaps = 13/85 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 EKL F + D + GYIT +++ L +D + +D Sbjct: 52 EKLKSTFLVLDEDGKGYITKEQLKK-------------GLEKDGLKLPYNFDLLLDQIDS 98 Query: 159 NEDGYITLDEFREGSKVDPSIIGAL 183 + G I EF + + L Sbjct: 99 DGSGKIDYTEFIAAALDRKQLSKKL 123 >3O4Y-A nrPDB Length = 196 Score = 84.3 bits (207), Expect = 3e-17, Method: Composition-based stats. Identities = 40/160 (25%), Positives = 75/160 (46%), Gaps = 13/160 (8%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDN 76 +QS +D ++++ + G + + K ++ P + L D D Sbjct: 47 QQSNDYDVQKLKAAFLHLDEEGK-GNITKLQLRKGLERSGLMLPPN--FDLLLDQIDSDG 103 Query: 77 NGFIHFEEFITVLSTTSRGTLEEKLSW-AFELYDLNHDGYITFDEMLTIVASVYKMMGSM 135 +G I + EF+ R L +KL + AF ++D+++DG IT E+ ++ + K G++ Sbjct: 104 SGNIDYTEFLAA--AIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNGNKR-GNI 160 Query: 136 VTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 + ++ VKK+ + +DKN DG I EF E K+ Sbjct: 161 TERDVNQ------VKKMIREVDKNGDGKIDFYEFSEMMKL 194 Score = 35.8 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 29/86 (33%), Gaps = 5/86 (5%) Query: 11 DDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPED----FAN 66 + L ++ I + F D G++ + + G+ + Sbjct: 111 EFLAAAIDRRQLSKKLIYCAFRVFDVDN-DGEITTAELAHVLFNGNKRGNITERDVNQVK 169 Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTT 92 + DK+ +G I F EF ++ T Sbjct: 170 KMIREVDKNGDGKIDFYEFSEMMKLT 195 >1LKJ-A nrPDB Length = 146 Score = 83.6 bits (205), Expect = 5e-17, Method: Composition-based stats. Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 11/108 (10%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F +FDKDNNG I E TV+ + E +++ D++ + I F E L Sbjct: 10 AEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFL 69 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 +++ K E + + FK+ DKN DG I+ E + Sbjct: 70 ALMSRQLKS-----------NDSEQELLEAFKVFDKNGDGLISAAELK 106 Score = 68.9 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 61/152 (40%), Gaps = 16/152 (10%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 T E ++ F +D +G ++ + + + E N L D D N Sbjct: 4 LTEEQIAEFKEAFALFDKDN-NGSISSSELATVMRSLG-LSPSEAEVNDLMNEIDVDGNH 61 Query: 79 FIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 I F EF+ ++S E++L AF+++D N DG I+ E+ ++ S+ Sbjct: 62 QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIG-------- 113 Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 E + V + + + + G I + +F Sbjct: 114 ----EKLTDAEVDDMLREVS-DGSGEINIQQF 140 Score = 52.7 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 34/93 (36%), Gaps = 1/93 (1%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + + Q+ +F+ + + E F VFDK+ +G I E VL++ Sbjct: 55 IDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGE 114 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 + ++ + G I + +++ Sbjct: 115 KLTDAEVDDMLREV-SDGSGEINIQQFAALLSK 146 Score = 42.7 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 37/97 (38%), Gaps = 19/97 (19%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D +++G I+ E+ T++ S+ + E V + +D Sbjct: 10 AEFKEAFALFDKDNNGSISSSELATVMRSLGL------------SPSEAEVNDLMNEIDV 57 Query: 159 NEDGYITLDEFREGSKV-------DPSIIGALNLYDG 188 + + I EF + ++ A ++D Sbjct: 58 DGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDK 94 >4DS7-A nrPDB Length = 147 Score = 82.4 bits (202), Expect = 1e-16, Method: Composition-based stats. Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 11/108 (10%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F +FDKDN+G I E TV+ + E +++ D++ + I F E L Sbjct: 11 AEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEAEVADLMNEIDVDGNHAIEFSEFL 70 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 +++ K E + + FK+ DKN DG I+ E + Sbjct: 71 ALMSRQLKC-----------NDSEQELLEAFKVFDKNGDGLISAAELK 107 Score = 71.2 bits (173), Expect = 3e-13, Method: Composition-based stats. Identities = 32/154 (20%), Positives = 63/154 (40%), Gaps = 16/154 (10%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDN 76 + T E ++ F +D SG ++ + + + E L D D Sbjct: 3 QNLTEEQIAEFKEAFALFDKDN-SGSISASELATVMRSLG-LSPSEAEVADLMNEIDVDG 60 Query: 77 NGFIHFEEFITVLSTTSR-GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSM 135 N I F EF+ ++S + E++L AF+++D N DG I+ E+ ++ S+ Sbjct: 61 NHAIEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIG------ 114 Query: 136 VTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 E + V ++ + + + G I + +F Sbjct: 115 ------EKLTDAEVDEMLREVS-DGSGEINIKQF 141 Score = 50.8 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 31/85 (36%), Gaps = 1/85 (1%) Query: 43 LAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS 102 + +F+ + + E F VFDK+ +G I E VL++ + ++ Sbjct: 64 IEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVD 123 Query: 103 WAFELYDLNHDGYITFDEMLTIVAS 127 + G I + +++ Sbjct: 124 EMLREV-SDGSGEINIKQFAALLSK 147 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 40/107 (37%), Gaps = 22/107 (20%) Query: 92 TSRGTLEE---KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMR 148 S+ EE + AF L+D ++ G I+ E+ T++ S+ + E Sbjct: 1 MSQNLTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLGL------------SPSEAE 48 Query: 149 VKKIFKLMDKNEDGYITLDEFREGSKV-------DPSIIGALNLYDG 188 V + +D + + I EF + ++ A ++D Sbjct: 49 VADLMNEIDVDGNHAIEFSEFLALMSRQLKCNDSEQELLEAFKVFDK 95 >2LHH-A nrPDB Length = 128 Score = 82.4 bits (202), Expect = 1e-16, Method: Composition-based stats. Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 11/108 (10%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F +FDKDNNG I E TV+ + E +++ D++ + I F E L Sbjct: 10 AEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFL 69 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 +++ K E + + FK+ DKN DG I+ E + Sbjct: 70 ALMSRQLKS-----------NDSEQELLEAFKVFDKNGDGLISAAELK 106 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 3/115 (2%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 T E ++ F +D +G ++ + + + E N L D D N Sbjct: 4 LTEEQIAEFKEAFALFDKDN-NGSISSSELATVMRSLG-LSPSEAEVNDLMNEIDVDGNH 61 Query: 79 FIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 I F EF+ ++S E++L AF+++D N DG I+ E+ ++ S+ + + Sbjct: 62 QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKL 116 Score = 42.7 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 27/68 (39%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + + Q+ +F+ + + E F VFDK+ +G I E VL++ Sbjct: 55 IDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGE 114 Query: 95 GTLEEKLS 102 + +L Sbjct: 115 KLTDAELE 122 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 37/97 (38%), Gaps = 19/97 (19%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D +++G I+ E+ T++ S+ + E V + +D Sbjct: 10 AEFKEAFALFDKDNNGSISSSELATVMRSLGL------------SPSEAEVNDLMNEIDV 57 Query: 159 NEDGYITLDEFREGSKV-------DPSIIGALNLYDG 188 + + I EF + ++ A ++D Sbjct: 58 DGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDK 94 >5MWC-D nrPDB Length = 311 Score = 81.6 bits (200), Expect = 2e-16, Method: Composition-based stats. Identities = 25/73 (34%), Positives = 35/73 (47%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 E+ + F FDKD +GFI EEF ++ T +E F D + +G I FD Sbjct: 148 PSEEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFD 207 Query: 120 EMLTIVASVYKMM 132 E L +V +V M Sbjct: 208 EFLKMVENVQLSM 220 Score = 68.2 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 12/84 (14%) Query: 90 STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRV 149 S T+ EE+LS F +D + DG+I +E I+ E + Sbjct: 142 SLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIRLTG------------EQLTDEDP 189 Query: 150 KKIFKLMDKNEDGYITLDEFREGS 173 +IF D +++G I DEF + Sbjct: 190 DEIFGDSDTDKNGRIDFDEFLKMV 213 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+ + + F +D G + RE+F I + + ED + +F D D NG I F Sbjct: 149 SEEELSECFRTFDKD-GDGFIDREEFGGIIRLTGEQLTDED-PDEIFGDSDTDKNGRIDF 206 Query: 83 EEFITVL 89 +EF+ ++ Sbjct: 207 DEFLKMV 213 >3QRX-A nrPDB Length = 169 Score = 81.2 bits (199), Expect = 2e-16, Method: Composition-based stats. Identities = 37/158 (23%), Positives = 65/158 (41%), Gaps = 15/158 (9%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 T ++EI++ F D SG + ++ + E + + DKD +G Sbjct: 22 LTEEQKQEIREAFDLFDTD-GSGTIDAKELKVAMRALGFEPKKE-EIKKMISEIDKDGSG 79 Query: 79 FIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 I FEEF+T+++ E++ AF L+D ++ G IT ++ V Sbjct: 80 TIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDL------------RRVA 127 Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E E ++++ D+N+D I DEF K Sbjct: 128 KELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIMKK 165 Score = 61.2 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 45/120 (37%) Query: 9 SKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHL 68 +K+ ++ + ++E + + SG + E+F+ + + Sbjct: 47 AKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKA 106 Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FD DN+G I ++ V EE+L D N D I DE + I+ Sbjct: 107 FRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIMKKT 166 Score = 34.3 bits (77), Expect = 0.037, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 R EI + + F D SG + +D ++ K+ + E+ + D++++ I Sbjct: 99 SREEILKAFRLFDDDN-SGTITIKDLRRVAKELGENLT-EEELQEMIAEADRNDDNEIDE 156 Query: 83 EEFITVLSTTS 93 +EFI ++ TS Sbjct: 157 DEFIRIMKKTS 167 >2BEC-A nrPDB Length = 202 Score = 80.9 bits (198), Expect = 3e-16, Method: Composition-based stats. Identities = 47/198 (23%), Positives = 77/198 (38%), Gaps = 38/198 (19%) Query: 1 MGAKTS--KLSKDDLTCLKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFV------- 49 MG+++S + D +++ T F + + + H F L G L+R D Sbjct: 1 MGSRSSHAAVIPDG-DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAV 59 Query: 50 -----KIYKQFFPFGSPE-------DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTL 97 +I + FFP GS H V D+D E + Sbjct: 60 NPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDED-------TETQDPKKPEPLNSR 112 Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 KL +AF+LYDL+ DG I+ EML ++ MV + E E + + D Sbjct: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLR-------LMVGVQVTEEQLENIADRTVQEAD 165 Query: 158 KNEDGYITLDEFREGSKV 175 ++ DG ++ EF + + Sbjct: 166 EDGDGAVSFVEFTKSLEK 183 >1S6I-A nrPDB Length = 188 Score = 80.5 bits (197), Expect = 4e-16, Method: Composition-based stats. Identities = 34/159 (21%), Positives = 60/159 (37%), Gaps = 16/159 (10%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDN 76 ++ + + +++ K D SG + ++ K+ E L D D Sbjct: 2 ERLSEEEIGGLKELFKMIDTDN-SGTITFDELKDGLKRVGSELM-ESEIKDLMDAADIDK 59 Query: 77 NGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 +G I + EFI ++ EE L AF +D + GYIT DE+ Sbjct: 60 SGTIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACK---------- 109 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 D ++ + + K +D++ DG I EF + Sbjct: 110 ----DFGLDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRK 144 >5H7D-E nrPDB Length = 120 Score = 79.3 bits (194), Expect = 9e-16, Method: Composition-based stats. Identities = 20/62 (32%), Positives = 32/62 (51%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F++FDKD +G I +E TV+ + + E +L D + +G I F E LT++ Sbjct: 59 KEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 118 Query: 126 AS 127 A Sbjct: 119 AR 120 Score = 50.0 bits (118), Expect = 5e-07, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 30/74 (40%), Gaps = 12/74 (16%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 AF L+D + DG IT E+ T++ S+ + E ++ + +D + + Sbjct: 59 KEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDADGN 106 Query: 162 GYITLDEFREGSKV 175 G I EF Sbjct: 107 GTIDFPEFLTMMAR 120 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 27/65 (41%), Gaps = 2/65 (3%) Query: 25 REIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE 84 + ++ F +D G + ++ + + + E + D D NG I F E Sbjct: 56 QAFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGNGTIDFPE 113 Query: 85 FITVL 89 F+T++ Sbjct: 114 FLTMM 118 >5COC-A nrPDB Length = 130 Score = 78.6 bits (192), Expect = 2e-15, Method: Composition-based stats. Identities = 21/68 (30%), Positives = 33/68 (48%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 63 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 122 Query: 123 TIVASVYK 130 T++A K Sbjct: 123 TMMARKMK 130 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 63 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 110 Query: 159 NEDGYITLDEFREGSKV 175 + +G I EF Sbjct: 111 DGNGTIDFPEFLTMMAR 127 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 32/82 (39%), Gaps = 2/82 (2%) Query: 13 LTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVF 72 L + + E ++ F +D G + ++ + + + E + Sbjct: 51 LNDAQAAAEECIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEV 108 Query: 73 DKDNNGFIHFEEFITVLSTTSR 94 D D NG I F EF+T+++ + Sbjct: 109 DADGNGTIDFPEFLTMMARKMK 130 >5E37-A nrPDB Length = 356 Score = 77.4 bits (189), Expect = 3e-15, Method: Composition-based stats. Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 26/141 (18%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTL---------EEKLSWAFELYDLNHD 113 + F + D D NG I EE +L + G + E++L E YD+N D Sbjct: 29 EELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVNKD 88 Query: 114 GYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE-- 171 G I+F+E I+ + G++ + FK +DK+ +G I E + Sbjct: 89 GVISFEEFKQIIYDGLLLEGTLA-----------EYESAFKAVDKSGNGTIGATELSKLF 137 Query: 172 GSKVDP----SIIGALNLYDG 188 S +P ++ + +YD Sbjct: 138 ASLGNPVSLEKLVDLMQMYDK 158 Score = 70.1 bits (170), Expect = 6e-13, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 63/175 (36%), Gaps = 23/175 (13%) Query: 23 DRREIQQWHKGFL--RDCPSGQLAREDFVKIYKQF--------FPFGSPEDFANHLFTVF 72 + ++++ + F +G + RE+ + + PED + Sbjct: 24 SKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQY 83 Query: 73 DKDNNGFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 D + +G I FEEF ++ + AF+ D + +G I E+ + AS+ Sbjct: 84 DVNKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASLGNP 143 Query: 132 MGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLY 186 + ++ + ++ DK++ G I EF + + + Y Sbjct: 144 VSL------------EKLVDLMQMYDKDDSGQIEFPEFLLMFRNSLLDLKDMTTY 186 >2LMV-A nrPDB Length = 148 Score = 77.4 bits (189), Expect = 4e-15, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 11/108 (10%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F FDK+ G I E T++ T + E +L + N++G + F E Sbjct: 10 AEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNGQLNFTEFC 69 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 I+A + E E +++ FK+ D++ DG+I+ E R Sbjct: 70 GIMAKQMR-----------ETDTEEEMREAFKIFDRDGDGFISPAELR 106 Score = 70.8 bits (172), Expect = 3e-13, Method: Composition-based stats. Identities = 32/156 (20%), Positives = 70/156 (44%), Gaps = 15/156 (9%) Query: 16 LKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKD 75 + + T E + F ++ +G++A + + + + E L + + Sbjct: 1 MSELTEEQIAEFKDAFVQFDKE-GTGKIATRELGTLMRTLGQNPT-EAELQDLIAEAENN 58 Query: 76 NNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 NNG ++F EF +++ R T EE++ AF+++D + DG+I+ E+ ++ Sbjct: 59 NNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVM--------- 109 Query: 135 MVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 +N E + + ++ + D + DG I +EF Sbjct: 110 ---INLGEKVTDEEIDEMIREADFDGDGMINYEEFV 142 Score = 68.2 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 43/106 (40%), Gaps = 1/106 (0%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+Q + +GQL +F I + E+ F +FD+D +GFI Sbjct: 44 TEAELQDLIAEA-ENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISP 102 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 E V+ +E++ D + DG I ++E + +++ Sbjct: 103 AELRFVMINLGEKVTDEEIDEMIREADFDGDGMINYEEFVWMISQK 148 >4Q57-A nrPDB Length = 65 Score = 74.3 bits (181), Expect = 3e-14, Method: Composition-based stats. Identities = 20/64 (31%), Positives = 32/64 (50%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 2 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 61 Query: 123 TIVA 126 T++A Sbjct: 62 TMMA 65 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 31/75 (41%), Gaps = 12/75 (16%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 2 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 49 Query: 159 NEDGYITLDEFREGS 173 + +G I EF Sbjct: 50 DGNGTIDFPEFLTMM 64 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 27/64 (42%), Gaps = 2/64 (3%) Query: 26 EIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEF 85 E ++ F +D G + ++ + + + E + D D NG I F EF Sbjct: 3 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGNGTIDFPEF 60 Query: 86 ITVL 89 +T++ Sbjct: 61 LTMM 64 >3IFK-A nrPDB Length = 90 Score = 73.9 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 11/92 (11%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 10 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 69 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 T++A K + E +++ F+ Sbjct: 70 TMMARKMK-----------DTDSEEEIREAFR 90 Score = 50.4 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 38/90 (42%), Gaps = 3/90 (3%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D N Sbjct: 3 QLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 60 Query: 78 GFIHFEEFITVLSTTSRGT-LEEKLSWAFE 106 G I F EF+T+++ + T EE++ AF Sbjct: 61 GTIDFPEFLTMMARKMKDTDSEEEIREAFR 90 Score = 43.5 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D + DG IT E+ T++ S+ + E ++ + +D Sbjct: 10 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ------------NPTEAELQDMINEVDA 57 Query: 159 NEDGYITLDEFREGSKV 175 + +G I EF Sbjct: 58 DGNGTIDFPEFLTMMAR 74 >2I08-A nrPDB Length = 78 Score = 73.5 bits (179), Expect = 4e-14, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 33/68 (48%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F+++DKD +G I +E TV+ + E +L D + +G I F E L Sbjct: 10 AEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFPEFL 69 Query: 123 TIVASVYK 130 T++A + K Sbjct: 70 TMMARIMK 77 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 30/77 (38%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF LYD + DG IT E+ T++ S+ E ++ + +D Sbjct: 10 AEFKEAFSLYDKDGDGTITTKELGTVMRSLGL------------NPTEAELQDMINEVDA 57 Query: 159 NEDGYITLDEFREGSKV 175 + +G I EF Sbjct: 58 DGNGTIDFPEFLTMMAR 74 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 32/79 (40%), Gaps = 2/79 (2%) Query: 16 LKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKD 75 + Q T E ++ + +D G + ++ + + + E + D D Sbjct: 1 MDQLTEEQIAEFKEAFSLYDKD-GDGTITTKELGTVMRSLGLNPT-EAELQDMINEVDAD 58 Query: 76 NNGFIHFEEFITVLSTTSR 94 NG I F EF+T+++ + Sbjct: 59 GNGTIDFPEFLTMMARIMK 77 >2LC5-A nrPDB Length = 151 Score = 72.8 bits (177), Expect = 9e-14, Method: Composition-based stats. Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 11/110 (10%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 + F +FDKDN+ + EE TV+ ++K+S + YD ++ G + Sbjct: 12 EQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKDNSGKFDQET 71 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 LTI+ + E +KK F++ DK ++GYI+ E + Sbjct: 72 FLTIMLEYGQ-----------EVDSTEDIKKAFEIFDKEKNGYISASELK 110 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 28/145 (19%), Positives = 67/145 (46%), Gaps = 6/145 (4%) Query: 14 TCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 K T +++E ++ + F +D + +L E+ + + + + + + +D Sbjct: 3 EQKKVLTAEEQQEYKEAFQLFDKDNDN-KLTAEELGTVMRALGANPTKQK-ISEIVKDYD 60 Query: 74 KDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 KDN+G E F+T++ + E + AFE++D +GYI+ E+ ++ ++ + + Sbjct: 61 KDNSGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTTLGEKL 120 Query: 133 GSMVTLNEDEATPEMRVKKIFKLMD 157 D+ E+ V++ +D Sbjct: 121 ---TEQEVDDLLKEIGVEEGLINVD 142 Score = 50.4 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 50/106 (47%), Gaps = 2/106 (1%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 +++I + K + +D SG+ +E F+ I ++ + F +FDK+ NG+I Sbjct: 48 TKQKISEIVKDYDKDN-SGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISA 106 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 E VL+T E+++ + + +G I D+ + ++ S Sbjct: 107 SELKHVLTTLGEKLTEQEVDDLLKEIGVE-EGLINVDDFVKLITSK 151 Score = 26.5 bits (57), Expect = 7.2, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 16/34 (47%) Query: 142 EATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 A + K+ F+L DK+ D +T +E + Sbjct: 9 TAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRA 42 >2RO8-A nrPDB Length = 79 Score = 72.8 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 32/68 (47%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F++FDKD +G I +E TV+ + + E +L D + +G I F E L Sbjct: 10 SEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 69 Query: 123 TIVASVYK 130 ++A K Sbjct: 70 NLMARKMK 77 Score = 46.2 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 31/79 (39%), Gaps = 2/79 (2%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 Q T E ++ F +D G + ++ + + + E + D D N Sbjct: 3 QLTDEQISEFKEAFSLFDKD-GDGCITTKELGTVMRSLGQNPT-EAELQDMINEVDADGN 60 Query: 78 GFIHFEEFITVLSTTSRGT 96 G I F EF+ +++ + T Sbjct: 61 GTIDFPEFLNLMARKMKDT 79 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 31/76 (40%), Gaps = 12/76 (15%) Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 + AF L+D + DG IT E+ T++ S+ + E ++ + +D + Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSLGQ------------NPTEAELQDMINEVDAD 58 Query: 160 EDGYITLDEFREGSKV 175 +G I EF Sbjct: 59 GNGTIDFPEFLNLMAR 74 >2LV7-A nrPDB Length = 100 Score = 72.0 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 3/80 (3%) Query: 51 IYKQFFPFGSPEDFANHL---FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFEL 107 + + P PED + F VFD+D NGFI +E T + + E +L + Sbjct: 21 LLSEQRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQR 80 Query: 108 YDLNHDGYITFDEMLTIVAS 127 D++ DG + F+E +T++ Sbjct: 81 LDMDGDGQVDFEEFVTLLGP 100 Score = 53.9 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 37/72 (51%), Gaps = 12/72 (16%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 E++ AF+++D + +G+I+ E+ T + S+ M E+ ++ I + +D Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPN------------EVELEVIIQRLDM 83 Query: 159 NEDGYITLDEFR 170 + DG + +EF Sbjct: 84 DGDGQVDFEEFV 95 Score = 33.1 bits (74), Expect = 0.075, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 21/40 (52%), Gaps = 3/40 (7%) Query: 136 VTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 V + EDE +++ FK+ D++ +G+I+ E + Sbjct: 28 VDIPEDEL---EEIREAFKVFDRDGNGFISKQELGTAMRS 64 >2LAP-A nrPDB Length = 167 Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 47/113 (41%), Gaps = 7/113 (6%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 + F FDKD +G+I+ + + T E +L + ++N G++ FD+ + Sbjct: 25 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFV 84 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 ++ G + + ++ F+ D N DG I+ E RE + Sbjct: 85 ELM-------GPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRK 130 Score = 67.8 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 57/159 (35%), Gaps = 18/159 (11%) Query: 22 FDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIH 81 + E+++ + F +D G + D + + + L + + G + Sbjct: 22 EEIEELREAFREFDKD-KDGYINCRDLGNCMRTMGYMPTEMELIE-LSQQINMNLGGHVD 79 Query: 82 FEEFITVLSTTSRGTLEE-----KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 F++F+ ++ + +L AF +D N DG I+ E+ + + Sbjct: 80 FDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGH- 138 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 +++I + +D N DG + +EF Sbjct: 139 ----------RDIEEIIRDVDLNGDGRVDFEEFVRMMSR 167 >3KF9-A nrPDB Length = 149 Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 63/158 (39%), Gaps = 15/158 (9%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 T ++EI++ F D SG + ++ + E + DKD +G Sbjct: 2 LTEEQKQEIREAFDLFDTD-GSGTIDAKELKVAMRALGFEPKKE-EIKKMIADIDKDGSG 59 Query: 79 FIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 I FEEF+ +++ E++ AF L+D + G I+F + + + Sbjct: 60 TIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELG-------- 111 Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E + ++++ D++ DG + +EF K Sbjct: 112 ----ENMTDEELQEMIDEADRDGDGEVNEEEFFRIMKK 145 Score = 58.5 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 35/94 (37%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + SG + E+F+++ + F +FD D G I F+ V Sbjct: 53 IDKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGE 112 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 +E+L + D + DG + +E I+ Sbjct: 113 NMTDEELQEMIDEADRDGDGEVNEEEFFRIMKKT 146 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 R EI + + F D +G+++ ++ ++ K+ ++ + D+D +G ++ Sbjct: 79 SREEIMKAFRLFDDD-ETGKISFKNLKRVAKELG-ENMTDEELQEMIDEADRDGDGEVNE 136 Query: 83 EEFITVLSTTS 93 EEF ++ TS Sbjct: 137 EEFFRIMKKTS 147 >2GGM-A nrPDB Length = 172 Score = 68.9 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 68/159 (42%), Gaps = 15/159 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 + T ++EI++ F D +G + ++ + E + + DK+ Sbjct: 24 ELTEEQKQEIREAFDLFDAD-GTGTIDVKELKVAMRALGFEPKKE-EIKKMISEIDKEGT 81 Query: 78 GFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G ++F +F+TV++ S +E++ AF+L+D + G I+F + + + Sbjct: 82 GKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELG------- 134 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E + ++++ D++ DG ++ EF K Sbjct: 135 -----ENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKK 168 Score = 57.4 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFE 83 + EI++ ++ +G++ DF+ + Q ++ F +FD D G I F+ Sbjct: 66 KEEIKKMISEIDKE-GTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFK 124 Query: 84 EFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 V +E+L + D + DG ++ E L I+ Sbjct: 125 NLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKT 169 Score = 35.4 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Query: 16 LKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKD 75 K S + EI + K F D +G+++ ++ ++ K+ + E+ + D+D Sbjct: 95 QKMSEKDTKEEILKAFKLFDDD-ETGKISFKNLKRVAKELGENLTDEELQEMI-DEADRD 152 Query: 76 NNGFIHFEEFITVLSTTS 93 +G + +EF+ ++ TS Sbjct: 153 GDGEVSEQEFLRIMKKTS 170 Score = 26.5 bits (57), Expect = 7.0, Method: Composition-based stats. Identities = 8/55 (14%), Positives = 17/55 (30%) Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 + M E + +++ F L D + G I + E + + Sbjct: 5 FKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRA 59 >3E3R-A nrPDB Length = 204 Score = 67.8 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 31/168 (18%), Positives = 64/168 (38%), Gaps = 16/168 (9%) Query: 27 IQQWHKGFLRDCPSGQ--LAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE 84 IQ + F + G L ++F + + A + +D++ +G + EE Sbjct: 36 IQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQ-AEAEGVCRKWDRNGSGTLDLEE 94 Query: 85 FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEAT 144 F+ L E ++ AF D + DG +T D++ + + + + E T Sbjct: 95 FLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSG-----RAHPKVRSGEWT 149 Query: 145 PEMRVKKIFKLMD-KNEDGYITLDEFRE-------GSKVDPSIIGALN 184 + +++ D +DG +TL EF++ D + + Sbjct: 150 EDEVLRRFLDNFDSSEKDGQVTLAEFQDYYSGVSASMNTDEEFVAMMT 197 >5D43-A nrPDB Length = 178 Score = 67.4 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 68/159 (42%), Gaps = 15/159 (9%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 + T ++E+++ F D SG + ++ + F ++ + + DK+ Sbjct: 24 ELTEDQKQEVREAFDLFDSD-GSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVDKEAT 81 Query: 78 GFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMV 136 G I F +F+ V++ + +E++ AF L+D + G I+F + V Sbjct: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR------------V 129 Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E+ + ++++ D++ DG + +EF + K Sbjct: 130 ANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 Score = 59.3 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 38/89 (42%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 +G+++ DF+ + Q ++ F +FD D G I F+ V + +E Sbjct: 81 TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDE 140 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASV 128 +L + D + DG + +E L I+ Sbjct: 141 ELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 Score = 26.5 bits (57), Expect = 6.4, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 15/37 (40%) Query: 139 NEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E + V++ F L D + G I + E + + Sbjct: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA 59 >2M29-A nrPDB Length = 171 Score = 67.0 bits (162), Expect = 5e-12, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 46/105 (43%), Gaps = 7/105 (6%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F FD D +G+I + E + T E +L + + G++ F+E + +++ Sbjct: 34 FEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELISPK 93 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 + + + ++ F+ DK+ DG IT+ E R+ + Sbjct: 94 LREETAHMLGV-------RELRIAFREFDKDRDGRITVAELRQAA 131 Score = 59.3 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 16/98 (16%) Query: 78 GFIHFEEFITVLSTTSRGTLEE-----KLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 GF+ FEEF+ ++S R +L AF +D + DG IT E+ ++ Sbjct: 79 GFVDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLG-- 136 Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 E + ++ + MD N DG I DEF Sbjct: 137 ---------EPLEGTELDEMLREMDLNGDGTIDFDEFV 165 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 35/91 (38%), Gaps = 5/91 (5%) Query: 41 GQLAREDFVKIYKQFFPFGSPE----DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT 96 G + E+FV++ + F FDKD +G I E Sbjct: 79 GFVDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEP 138 Query: 97 LE-EKLSWAFELYDLNHDGYITFDEMLTIVA 126 LE +L DLN DG I FDE + +++ Sbjct: 139 LEGTELDEMLREMDLNGDGTIDFDEFVMMLS 169 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 29/68 (42%), Gaps = 1/68 (1%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFE 83 RE++ + F +D G++ + + + + D + +G I F+ Sbjct: 104 VRELRIAFREFDKD-RDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTIDFD 162 Query: 84 EFITVLST 91 EF+ +LST Sbjct: 163 EFVMMLST 170 Score = 26.2 bits (56), Expect = 9.2, Method: Composition-based stats. Identities = 7/23 (30%), Positives = 12/23 (52%) Query: 152 IFKLMDKNEDGYITLDEFREGSK 174 F+ D ++DGYI E + + Sbjct: 33 AFEEFDTDQDGYIGYRELGDCMR 55 >2AMI-A nrPDB Length = 96 Score = 66.2 bits (160), Expect = 8e-12, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 28/69 (40%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 + F +FD D +G I +E + +E++ D + G I F+E Sbjct: 28 QKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEE 87 Query: 121 MLTIVASVY 129 LT++ + Sbjct: 88 FLTMMTAKM 96 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 T ++EI++ F D SG + ++ + E + + DKD +G Sbjct: 24 LTEEQKQEIREAFDLFDTD-GSGTIDAKELKVAMRALGFEPKKE-EIKKMISEIDKDGSG 81 Query: 79 FIHFEEFITVLST 91 I FEEF+T+++ Sbjct: 82 TIDFEEFLTMMTA 94 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 31/76 (40%), Gaps = 12/76 (15%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 ++++ AF+L+D + G I E+ + ++ +KK+ +D Sbjct: 29 KQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKK------------EEIKKMISEID 76 Query: 158 KNEDGYITLDEFREGS 173 K+ G I +EF Sbjct: 77 KDGSGTIDFEEFLTMM 92 Score = 27.3 bits (59), Expect = 4.5, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 23/54 (42%), Gaps = 3/54 (5%) Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 T+V++ V L E++ + +++ F L D + G I E + + Sbjct: 8 KTVVSARRDQKKGRVGLTEEQ---KQEIREAFDLFDTDGSGTIDAKELKVAMRA 58 >5ZOR-A nrPDB Length = 149 Score = 66.2 bits (160), Expect = 9e-12, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 62/153 (40%), Gaps = 14/153 (9%) Query: 22 FDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIH 81 +I++ F D SG + E+ K P D + + NG I Sbjct: 4 LTDEQIREAFNLFDAD-GSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIE 62 Query: 82 FEEFITVL-STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNE 140 + EF ++ S ++ E++ AF+L+DL+ G I+F + + + Sbjct: 63 YGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLG----------- 111 Query: 141 DEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 E + ++++ D++ DG ++ +EF+ Sbjct: 112 -ENPGDDVLQEMIAEADEDGDGEVSFEEFKSVM 143 Score = 59.3 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 34/93 (36%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + +G + +F ++ K + F +FD D G I F V Sbjct: 53 MNTNANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGE 112 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 ++ L D + DG ++F+E +++ Sbjct: 113 NPGDDVLQEMIAEADEDGDGEVSFEEFKSVMMQ 145 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 43/114 (37%), Gaps = 12/114 (10%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRG-TLEEKLSWAFELYDLNHDGYITFDEM 121 + F +FD D +G I EE + G +++ + N +G I + E Sbjct: 7 EQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYGEF 66 Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 +V S + V K F+L D ++ G I+ +E +K+ Sbjct: 67 ERMVKSRMA-----------QKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKL 109 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 37/100 (37%), Gaps = 18/100 (18%) Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 +E++ AF L+D + G I +EM + + P V++ + Sbjct: 3 ALTDEQIREAFNLFDADGSGAIDAEEMALAMKGLGFG-----------DLPRDEVERTVR 51 Query: 155 LMDKNEDGYITLDEFREGSKVD-------PSIIGALNLYD 187 M+ N +G I EF K ++ A L+D Sbjct: 52 SMNTNANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFD 91 >2KSZ-A nrPDB Length = 76 Score = 65.5 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 22/63 (34%), Positives = 33/63 (52%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F +FDKD +G I EE TV+ + + EE+L D + +G I FDE L+++ Sbjct: 13 KEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLM 72 Query: 126 ASV 128 A Sbjct: 73 AKK 75 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 32/74 (43%), Gaps = 12/74 (16%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 AF L+D + DG IT +E+ T++ + D+ E ++ + +D + + Sbjct: 13 KEAFGLFDKDGDGCITVEELATVI------------RSLDQNPTEEELQDMISEVDADGN 60 Query: 162 GYITLDEFREGSKV 175 G I DEF Sbjct: 61 GTIEFDEFLSLMAK 74 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 32/71 (45%), Gaps = 2/71 (2%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 + + ++ F +D G + E+ + + + E+ + + + D D NG Sbjct: 4 LSEEQIVDFKEAFGLFDKD-GDGCITVEELATVIRSLDQNPTEEELQDMI-SEVDADGNG 61 Query: 79 FIHFEEFITVL 89 I F+EF++++ Sbjct: 62 TIEFDEFLSLM 72 >2OBH-A nrPDB Length = 143 Score = 63.9 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 67/157 (42%), Gaps = 15/157 (9%) Query: 20 TYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGF 79 T ++EI++ F D +G + ++ + E + + DK+ G Sbjct: 1 TEEQKQEIREAFDLFDAD-GTGTIDVKELKVAMRALGFEPKKE-EIKKMISEIDKEGTGK 58 Query: 80 IHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTL 138 ++F +F+TV++ S +E++ AF+L+D + G I+F + + + Sbjct: 59 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELG--------- 109 Query: 139 NEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E + ++++ D++ DG ++ EF K Sbjct: 110 ---ENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKK 143 >1F55-A nrPDB Length = 77 Score = 63.9 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 31/68 (45%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 F +FDKDNNG I E TV+ + E +++ D++ + I F E L Sbjct: 10 AEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFL 69 Query: 123 TIVASVYK 130 +++ K Sbjct: 70 ALMSRQLK 77 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 30/77 (38%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF L+D +++G I+ E+ T++ S+ + E V + +D Sbjct: 10 AEFKEAFALFDKDNNGSISSSELATVMRSLGL------------SPSEAEVNDLMNEIDV 57 Query: 159 NEDGYITLDEFREGSKV 175 + + I EF Sbjct: 58 DGNHQIEFSEFLALMSR 74 Score = 41.2 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 T E ++ F +D +G ++ + + + E N L D D N Sbjct: 4 LTEEQIAEFKEAFALFDKDN-NGSISSSELATVMRSLG-LSPSEAEVNDLMNEIDVDGNH 61 Query: 79 FIHFEEFITVLS 90 I F EF+ ++S Sbjct: 62 QIEFSEFLALMS 73 >1TNP-A nrPDB Length = 90 Score = 62.8 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 19/63 (30%), Positives = 29/63 (46%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FD D G I +E TV+ + +E+L E D + G I F+E L ++ Sbjct: 26 FDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQ 85 Query: 129 YKM 131 K Sbjct: 86 MKE 88 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 33/84 (39%), Gaps = 2/84 (2%) Query: 6 SKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFA 65 + ++ + E + F D G ++ ++ + + + E+ Sbjct: 1 ASMTDQQAEARAFLSEEMIAEFKAAFDMFDADGG-GDISTKELGTVMRMLGQNPTKEEL- 58 Query: 66 NHLFTVFDKDNNGFIHFEEFITVL 89 + + D+D +G I FEEF+ ++ Sbjct: 59 DAIIEEVDEDGSGTIDFEEFLVMM 82 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 32/86 (37%), Gaps = 12/86 (13%) Query: 90 STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRV 149 + + AF+++D + G I+ E+ T++ + + + + Sbjct: 11 RAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQ------------NPTKEEL 58 Query: 150 KKIFKLMDKNEDGYITLDEFREGSKV 175 I + +D++ G I +EF Sbjct: 59 DAIIEEVDEDGSGTIDFEEFLVMMVR 84 >1TRF-A nrPDB Length = 76 Score = 62.8 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 29/62 (46%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 F +FD D G I +E TV+ + +E+L E D + G I F+E L ++ Sbjct: 15 FDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQ 74 Query: 129 YK 130 K Sbjct: 75 MK 76 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 30/71 (42%), Gaps = 2/71 (2%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 + E + F D G ++ ++ + + + E+ + + D+D +G Sbjct: 3 LSEEMIAEFKAAFDMFDADGG-GDISTKELGTVMRMLGQNPTKEEL-DAIIEEVDEDGSG 60 Query: 79 FIHFEEFITVL 89 I FEEF+ ++ Sbjct: 61 TIDFEEFLVMM 71 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + AF+++D + G I+ E+ T++ + + + + I + +D+ Sbjct: 9 AEFKAAFDMFDADGGGDISTKELGTVMRMLGQ------------NPTKEELDAIIEEVDE 56 Query: 159 NEDGYITLDEFREGSKV 175 + G I +EF Sbjct: 57 DGSGTIDFEEFLVMMVR 73 >1JC2-A nrPDB Length = 76 Score = 62.8 bits (151), Expect = 9e-11, Method: Composition-based stats. Identities = 25/70 (35%), Positives = 37/70 (52%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 G E+ + F +FDK+ +GFI EE +L T +EE + + D N+DG I F Sbjct: 6 GKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDF 65 Query: 119 DEMLTIVASV 128 DE L ++ V Sbjct: 66 DEFLKMMEGV 75 Score = 53.1 bits (126), Expect = 7e-08, Method: Composition-based stats. Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 12/80 (15%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 +G EE+L+ F ++D N DG+I +E+ I+ + E E ++ + Sbjct: 5 KGKSEEELANCFRIFDKNADGFIDIEELGEILRATG------------EHVIEEDIEDLM 52 Query: 154 KLMDKNEDGYITLDEFREGS 173 K DKN DG I DEF + Sbjct: 53 KDSDKNNDGRIDFDEFLKMM 72 Score = 27.3 bits (59), Expect = 3.9, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 + + + E + F++ DKN DG+I ++E E Sbjct: 1 MEDAKGKSEEELANCFRIFDKNADGFIDIEELGE 34 >2M97-A nrPDB Length = 69 Score = 62.8 bits (151), Expect = 9e-11, Method: Composition-based stats. Identities = 24/68 (35%), Positives = 36/68 (52%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 E+ + F +FDKD NGFI EEF ++ T +E + F D + +G I FDE Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDE 60 Query: 121 MLTIVASV 128 L ++ +V Sbjct: 61 FLKMMENV 68 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 12/77 (15%) Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 EE+LS F ++D + +G+I +E I+ E + V +IF Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTG------------EQLTDEDVDEIFGDS 48 Query: 157 DKNEDGYITLDEFREGS 173 D +++G I DEF + Sbjct: 49 DTDKNGRIDFDEFLKMM 65 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+ + + F +D +G + RE+F I + + ED + +F D D NG I F Sbjct: 1 SEEELSECFRIFDKD-GNGFIDREEFGDIIRLTGEQLTDED-VDEIFGDSDTDKNGRIDF 58 Query: 83 EEFITVL 89 +EF+ ++ Sbjct: 59 DEFLKMM 65 >2HF5-A nrPDB Length = 68 Score = 62.8 bits (151), Expect = 9e-11, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 +L D + +G I F E LT++A K + E +++ F++ DK Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMK-----------DTDSEEEIREAFRVFDK 49 Query: 159 NEDGYITLDEFREGS 173 + +GYI+ E R Sbjct: 50 DGNGYISAAELRHVM 64 Score = 59.3 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEM 121 + D D NG I F EF+T+++ + T EE++ AF ++D + +GYI+ E+ Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 Query: 122 LTIVASV 128 ++ ++ Sbjct: 61 RHVMTNL 67 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 24/54 (44%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTS 93 +G + +F+ + + E+ F VFDKD NG+I E V++ Sbjct: 15 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 68 Score = 26.5 bits (57), Expect = 7.1, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 11/28 (39%) Query: 148 RVKKIFKLMDKNEDGYITLDEFREGSKV 175 ++ + +D + +G I EF Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMAR 29 >2KN2-A nrPDB Length = 92 Score = 62.4 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 34/71 (47%) Query: 58 FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYIT 117 E+ F VFDKD NG+I E V+ +E++ + DL+ DG + Sbjct: 4 DTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVN 63 Query: 118 FDEMLTIVASV 128 ++E + ++ +V Sbjct: 64 YEEFVKMMMTV 74 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 38/76 (50%), Gaps = 12/76 (15%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 EE+L AF+++D + +GYI+ E+ ++ +N E + V+++ K D Sbjct: 8 EEELKEAFKVFDKDQNGYISASELRHVM------------INLGEKLTDEEVEQMIKEAD 55 Query: 158 KNEDGYITLDEFREGS 173 + DG + +EF + Sbjct: 56 LDGDGQVNYEEFVKMM 71 Score = 34.3 bits (77), Expect = 0.034, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 19/32 (59%) Query: 142 EATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 + E +K+ FK+ DK+++GYI+ E R Sbjct: 4 DTDAEEELKEAFKVFDKDQNGYISASELRHVM 35 >2KZ2-A nrPDB Length = 94 Score = 62.0 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 34/77 (44%) Query: 52 YKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLN 111 ++ E+ F V DKD NG+I E V++ +E++ D++ Sbjct: 18 FQSLMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADID 77 Query: 112 HDGYITFDEMLTIVASV 128 DG + ++E + ++ + Sbjct: 78 GDGQVNYEEFVQMMTAK 94 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 35/84 (41%), Gaps = 12/84 (14%) Query: 90 STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRV 149 S EE++ AF + D + +GYI+ E+ ++ N E + V Sbjct: 20 SLMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMT------------NLGEKLTDEEV 67 Query: 150 KKIFKLMDKNEDGYITLDEFREGS 173 ++ + D + DG + +EF + Sbjct: 68 DEMIREADIDGDGQVNYEEFVQMM 91 >5ZGM-A nrPDB Length = 110 Score = 62.0 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 7/83 (8%) Query: 52 YKQFFPF----GSPEDFANHLFTVFDKDNNGFIHFEEFITVL---STTSRGTLEEKLSWA 104 YK+FF G E +F + DKD +GFI EE +VL S R + + Sbjct: 27 YKRFFQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTETKAL 86 Query: 105 FELYDLNHDGYITFDEMLTIVAS 127 D +HDG I DE +VA Sbjct: 87 LAAGDSDHDGKIGADEFAKMVAQ 109 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 41/96 (42%), Gaps = 11/96 (11%) Query: 78 GFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 G ++ F ++ +G E ++ FE+ D + G+I +E+ +++ + G ++ Sbjct: 23 GTFDYKRFFQLVGL--KGKSEAQVKEVFEILDKDQSGFIEEEELKSVL-KGFSAHGRDLS 79 Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 E K + D + DG I DEF + Sbjct: 80 DTE--------TKALLAAGDSDHDGKIGADEFAKMV 107 Score = 26.9 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 21/30 (70%) Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 E +VK++F+++DK++ G+I +E + K Sbjct: 40 SEAQVKEVFEILDKDQSGFIEEEELKSVLK 69 >1FW4-A nrPDB Length = 71 Score = 61.2 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 33/71 (46%) Query: 58 FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYIT 117 E+ F VFDKD NG+I E V++ +E++ D++ DG + Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 60 Query: 118 FDEMLTIVASV 128 ++E + ++ + Sbjct: 61 YEEFVQMMTAK 71 Score = 52.7 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 35/77 (45%), Gaps = 12/77 (15%) Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 EE++ AF ++D + +GYI+ E+ ++ N E + V ++ + Sbjct: 4 SEEEIREAFRVFDKDGNGYISAAELRHVMT------------NLGEKLTDEEVDEMIREA 51 Query: 157 DKNEDGYITLDEFREGS 173 D + DG + +EF + Sbjct: 52 DIDGDGQVNYEEFVQMM 68 Score = 34.3 bits (77), Expect = 0.034, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 18/32 (56%) Query: 142 EATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 + E +++ F++ DK+ +GYI+ E R Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 32 >2BL0-B nrPDB Length = 145 Score = 60.8 bits (146), Expect = 3e-10, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 47/145 (32%), Gaps = 47/145 (32%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS-------------------- 102 D F +FDKDN+G + EE + L + + +L+ Sbjct: 5 DQIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTIKGQLNAKEFDLATFKTVY 64 Query: 103 ---------------WAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEM 147 AF D +G I E+ ++ LN +A Sbjct: 65 RKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLL------------LNLGDALTSS 112 Query: 148 RVKKIFKLMDKNEDGYITLDEFREG 172 V+++ K + + DG I + F + Sbjct: 113 EVEELMKEVSVSGDGAINYESFVDM 137 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 42/99 (42%), Gaps = 10/99 (10%) Query: 41 GQLAREDF-----VKIYKQFFPFGSPEDFANHLFTVF---DKDNNGFIHFEEFITVLSTT 92 GQL ++F +Y++ P +P + + + F DK+ NG I E +L Sbjct: 48 GQLNAKEFDLATFKTVYRK--PIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNL 105 Query: 93 SRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 ++ + ++ DG I ++ + ++ + Y + Sbjct: 106 GDALTSSEVEELMKEVSVSGDGAINYESFVDMLVTGYPL 144 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 6/33 (18%), Positives = 18/33 (54%) Query: 143 ATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 ++++ F++ DK+ DG ++++E + Sbjct: 1 TASADQIQECFQIFDKDNDGKVSIEELGSALRS 33 >2JNF-A nrPDB Length = 158 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 32/163 (19%), Positives = 61/163 (37%), Gaps = 18/163 (11%) Query: 13 LTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVF 72 + + + + + ++ + F SG+++ + + I + + L F Sbjct: 1 MGDVSKLSSNQVKLLETAFRDFETPEGSGRVSTDQ-IGIILEVLGIQQTKSTIRQLIDEF 59 Query: 73 DKDNNGFIHFEEF-ITVLSTTSRG----TLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 D NG I F+ F I ++++L AF LYD +GYI+ D M I+A Sbjct: 60 DPFGNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILA- 118 Query: 128 VYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 DE + + +D + G + +EF Sbjct: 119 -----------ELDETLSSEDLDAMIDEIDADGSGTVDFEEFM 150 Score = 54.7 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 42/112 (37%), Gaps = 8/112 (7%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFG----SPEDFANHLFTVFD 73 Q T R++ F +G + + F I +F + F ++D Sbjct: 46 QQTKSTIRQLIDEFDPF----GNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYD 101 Query: 74 KDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 K+ NG+I + +L+ E L + D + G + F+E + ++ Sbjct: 102 KEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVM 153 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 46/124 (37%), Gaps = 8/124 (6%) Query: 63 DFANHLFTVFDK-DNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 F F+ + +G + ++ +L + + + +D +G I FD Sbjct: 13 KLLETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLIDEFDPFGNGDIDFDSF 72 Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIG 181 I A + + + +++ F+L DK +GYI+ D RE + Sbjct: 73 KIIGAR-------FLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAELDETLS 125 Query: 182 ALNL 185 + +L Sbjct: 126 SEDL 129 >1Y1X-A nrPDB Length = 191 Score = 60.1 bits (144), Expect = 6e-10, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 46/155 (29%), Gaps = 18/155 (11%) Query: 51 IYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDL 110 +Y + F D D +G I E LS+ +YD Sbjct: 15 VYAPSARHMNDNQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDK 74 Query: 111 NHDGYITFDEMLTI------VASVYKMMGSMVTLNEDEA------------TPEMRVKKI 152 NH G ITFDE + + ++ S D E + + Sbjct: 75 NHSGEITFDEFKDLHHFILSMREGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQAL 134 Query: 153 FKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYD 187 + D+ G + D++ E S + YD Sbjct: 135 MRKFDRQRRGSLGFDDYVELSIFVCRVRNVFAFYD 169 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 42/127 (33%), Gaps = 25/127 (19%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 SG++ ++F ++ F E F D +G + E L ++ E+ Sbjct: 77 SGEITFDEFKDLHH--FILSMREGFRKR-----DSSGDGRLDSNEVRAALLSSGYQVSEQ 129 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 +D G + FD+ + + + RV+ +F D+ Sbjct: 130 TFQALMRKFDRQRRGSLGFDDYVEL------------------SIFVCRVRNVFAFYDRE 171 Query: 160 EDGYITL 166 G +T Sbjct: 172 RTGQVTF 178 >4N5X-A nrPDB Length = 199 Score = 59.7 bits (143), Expect = 7e-10, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 40/109 (36%), Gaps = 17/109 (15%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 LF D++ +G + E L ++ F D+N DG + F+E + + Sbjct: 25 ETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYL 84 Query: 126 ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 E ++K FK +DKN DG I E + + Sbjct: 85 K-----------------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQ 116 Score = 43.1 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 33/85 (38%), Gaps = 6/85 (7%) Query: 36 RDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRG 95 G+L E+F+K K E F DK+N+G I E + L T Sbjct: 68 DVNKDGKLDFEEFMKYLK------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLT 121 Query: 96 TLEEKLSWAFELYDLNHDGYITFDE 120 E++ + D++ + ++E Sbjct: 122 ISEQQAELILQSIDVDGTMTVDWNE 146 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 36/99 (36%), Gaps = 12/99 (12%) Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDE 142 +F+ + + + F+ D N DG + E+ + ++ +G Sbjct: 6 RDFVLPTAASQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE----- 60 Query: 143 ATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIG 181 +KIF D N+DG + +EF + K + Sbjct: 61 -------EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMK 92 >4ZCV-A nrPDB Length = 165 Score = 59.7 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 40/109 (36%), Gaps = 17/109 (15%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 LF D++ +G + E L ++ F D+N DG + F+E + + Sbjct: 16 ETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYL 75 Query: 126 ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 E ++K FK +DKN DG I E + + Sbjct: 76 K-----------------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQ 107 Score = 43.1 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 33/85 (38%), Gaps = 6/85 (7%) Query: 36 RDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRG 95 G+L E+F+K K E F DK+N+G I E + L T Sbjct: 59 DVNKDGKLDFEEFMKYLK------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLT 112 Query: 96 TLEEKLSWAFELYDLNHDGYITFDE 120 E++ + D++ + ++E Sbjct: 113 ISEQQAELILQSIDVDGTMTVDWNE 137 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 30/80 (37%), Gaps = 12/80 (15%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 F+ D N DG + E+ + ++ +G +KIF D N+D Sbjct: 16 ETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE------------EKIFTTGDVNKD 63 Query: 162 GYITLDEFREGSKVDPSIIG 181 G + +EF + K + Sbjct: 64 GKLDFEEFMKYLKDHEKKMK 83 >1JFJ-A nrPDB Length = 134 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 23/133 (17%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A LF D + +G + +EE +S E+ L F+ D + +G I +E Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKF 61 Query: 125 VASV-----------YKMMGSMVTLNEDEATPEMRVKKIFK------------LMDKNED 161 S+ K++ ++ ++ D + V FK D N D Sbjct: 62 YGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKADANGD 121 Query: 162 GYITLDEFREGSK 174 GYITL+EF E S Sbjct: 122 GYITLEEFLEFSL 134 Score = 26.2 bits (56), Expect = 8.0, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 16/30 (53%) Query: 150 KKIFKLMDKNEDGYITLDEFREGSKVDPSI 179 + +FK +D N DG ++ +E + +I Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAI 32 >2RO9-A nrPDB Length = 69 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 33/69 (47%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 E+ F VFDKD NGFI E V++ +E++ D++ DG I ++ Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 120 EMLTIVASV 128 E + ++ + Sbjct: 61 EFVKVMMAK 69 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 35/79 (44%), Gaps = 12/79 (15%) Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 EE+L AF ++D + +G+I+ E+ ++ N E + V ++ + Sbjct: 2 SEEELKEAFRVFDKDQNGFISAAELRHVMT------------NLGEKLTDEEVDEMIREA 49 Query: 157 DKNEDGYITLDEFREGSKV 175 D + DG I +EF + Sbjct: 50 DVDGDGQINYEEFVKVMMA 68 Score = 30.0 bits (66), Expect = 0.66, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 18/30 (60%) Query: 144 TPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 E +K+ F++ DK+++G+I+ E R Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVM 30 >2JNX-A nrPDB Length = 134 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 9/104 (8%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A LF D + +G + +EE +S+ E+ L F+ D++ +G I E Sbjct: 2 AEALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKF 61 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE 168 A+V +D + ++ +K ++KLMD + DG +T +E Sbjct: 62 AAAV---------KEQDLSDEKVGLKILYKLMDADGDGKLTKEE 96 Score = 58.1 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 37/139 (26%), Positives = 52/139 (37%), Gaps = 20/139 (14%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFIT-VLSTTS 93 L G ++ E+ P E +F D D NG I EF + Sbjct: 9 LDANGDGSVSYEEVKAFVSSKRPI-KNEQLLQLIFKAIDIDGNGEIDLAEFTKFAAAVKE 67 Query: 94 RGTLEEK--LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKK 151 + +EK L ++L D + DG +T +E+ T E V + Sbjct: 68 QDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFG---------------YEKVVDQ 112 Query: 152 IFKLMDKNEDGYITLDEFR 170 I K D N DGYITL+EF Sbjct: 113 IMK-ADANGDGYITLEEFL 130 Score = 41.2 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 37/102 (36%), Gaps = 6/102 (5%) Query: 25 REIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANH--LFTVFDKDNNGFIHF 82 ++ Q + +G++ +F K ++ L+ + D D +G + Sbjct: 35 EQLLQLIFKAIDIDGNGEIDLAEFTKFAAAVKEQDLSDEKVGLKILYKLMDADGDGKLTK 94 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 EE T EK+ D N DGYIT +E L Sbjct: 95 EEVTTFFKKFGY----EKVVDQIMKADANGDGYITLEEFLAF 132 Score = 39.6 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 12/68 (17%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 F+ D N DG ++++E+ V+S + E ++ IFK +D + + Sbjct: 3 EALFKQLDANGDGSVSYEEVKAFVSSKRPIKN------------EQLLQLIFKAIDIDGN 50 Query: 162 GYITLDEF 169 G I L EF Sbjct: 51 GEIDLAEF 58 >2ROB-A nrPDB Length = 70 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 34/69 (49%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 E+ F VFDKD NG+I E V+ +E++ + DL+ DG + ++ Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 60 Query: 120 EMLTIVASV 128 E + ++ +V Sbjct: 61 EFVKMMMTV 69 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 38/76 (50%), Gaps = 12/76 (15%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 EE+L AF+++D + +GYI+ E+ ++ +N E + V+++ K D Sbjct: 3 EEELKEAFKVFDKDQNGYISASELRHVM------------INLGEKLTDEEVEQMIKEAD 50 Query: 158 KNEDGYITLDEFREGS 173 + DG + +EF + Sbjct: 51 LDGDGQVNYEEFVKMM 66 Score = 30.8 bits (68), Expect = 0.37, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 18/30 (60%) Query: 144 TPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 E +K+ FK+ DK+++GYI+ E R Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVM 30 >2BL0-C nrPDB Length = 142 Score = 58.5 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 39/116 (33%), Gaps = 11/116 (9%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 F +FD + GFI E TVL + F D +G I F Sbjct: 2 DDQVSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQF 61 Query: 119 DEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 E L+++ K + T E +++ F+ D GYI ++ Sbjct: 62 PEFLSMMGRRMK-----------QTTSEDILRQAFRTFDPEGTGYIPKAALQDALL 106 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 3/114 (2%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E ++ + F + +G + +E + KQF P F N +F D NG I F Sbjct: 4 QVSEFKEAFELFDSE-RTGFITKEGLQTVLKQFGVRVEPAAF-NEMFNEADATGNGKIQF 61 Query: 83 EEFITVL-STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSM 135 EF++++ + T E+ L AF +D GYI + + ++ + Sbjct: 62 PEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNLGDRLKPH 115 Score = 35.8 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 30/86 (34%), Gaps = 1/86 (1%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 +G++ +F+ + + + ED F FD + G+I L Sbjct: 56 NGKIQFPEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNLGDRLKPH 115 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIV 125 + + + + G I +D + + Sbjct: 116 EFAEFLGITETEK-GQIRYDNFINTM 140 >1OZS-A nrPDB Length = 73 Score = 58.1 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 36/70 (51%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 G E+ + LF +FDK+ +G+I EE +L T E+ + + D N+DG I + Sbjct: 3 GKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDY 62 Query: 119 DEMLTIVASV 128 DE L + V Sbjct: 63 DEFLEFMKGV 72 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 12/81 (14%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 +G EE+LS F ++D N DGYI +E+ ++ + E E ++++ Sbjct: 2 KGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATG------------ETITEDDIEELM 49 Query: 154 KLMDKNEDGYITLDEFREGSK 174 K DKN DG I DEF E K Sbjct: 50 KDGDKNNDGRIDYDEFLEFMK 70 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E+ + F ++ G + E+ KI Q ED L DK+N+G I + Sbjct: 5 SEEELSDLFRMFDKNA-DGYIDLEEL-KIMLQATGETITEDDIEELMKDGDKNNDGRIDY 62 Query: 83 EEFITVLS 90 +EF+ + Sbjct: 63 DEFLEFMK 70 Score = 28.5 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 18/31 (58%) Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E + +F++ DKN DGYI L+E + + Sbjct: 5 SEEELSDLFRMFDKNADGYIDLEELKIMLQA 35 >2M5E-A nrPDB Length = 73 Score = 57.8 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 33/73 (45%) Query: 56 FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 E+ F VFD+D NG I E V++ ++++ D++ DG+ Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGH 60 Query: 116 ITFDEMLTIVASV 128 I ++E + ++ S Sbjct: 61 INYEEFVRMMVSK 73 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 35/82 (42%), Gaps = 12/82 (14%) Query: 92 TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKK 151 EE+L AF+++D + +G I+ E+ ++ N E + V + Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMT------------NLGEKLTDDEVDE 48 Query: 152 IFKLMDKNEDGYITLDEFREGS 173 + + D + DG+I +EF Sbjct: 49 MIREADIDGDGHINYEEFVRMM 70 >5VLN-A nrPDB Length = 120 Score = 57.4 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 39/90 (43%), Gaps = 1/90 (1%) Query: 14 TCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 ++Q T + E + F+ G ++ ++ K+ + +PE+ + D Sbjct: 7 AAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMI-DEVD 65 Query: 74 KDNNGFIHFEEFITVLSTTSRGTLEEKLSW 103 +D +G + F+EF+ ++ + + + K Sbjct: 66 EDGSGTVDFDEFLVMMVRSMKDDSKGKFKR 95 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 28/73 (38%), Gaps = 4/73 (5%) Query: 62 EDFANHLFTVFDK----DNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYIT 117 E+ N FD +G I +E V+ + E+L + D + G + Sbjct: 14 EEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVD 73 Query: 118 FDEMLTIVASVYK 130 FDE L ++ K Sbjct: 74 FDEFLVMMVRSMK 86 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 26/63 (41%), Gaps = 12/63 (19%) Query: 113 DGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 DG I+ E+ ++ +M+G T ++++ +D++ G + DEF Sbjct: 33 DGSISTKELGKVM----RMLGQNPTP--------EELQEMIDEVDEDGSGTVDFDEFLVM 80 Query: 173 SKV 175 Sbjct: 81 MVR 83 >2B1U-A nrPDB Length = 71 Score = 57.4 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 29/59 (49%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 F FD+D +G I +E ++ + +E+L D++ DG + ++E ++A Sbjct: 12 FRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARMLAQ 70 Score = 50.0 bits (118), Expect = 5e-07, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 12/78 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 E L AF +D + DG+IT DE+ +A + + + P+ + + + D Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPL------------PQEELDAMIREADV 53 Query: 159 NEDGYITLDEFREGSKVD 176 ++DG + +EF + Sbjct: 54 DQDGRVNYEEFARMLAQE 71 Score = 42.0 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 25 REIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE 84 ++Q + F +D G + ++ + P++ + + D D +G +++EE Sbjct: 6 EDLQVAFRAFDQD-GDGHITVDELRRAMAGLGQ-PLPQEELDAMIREADVDQDGRVNYEE 63 Query: 85 FITVL 89 F +L Sbjct: 64 FARML 68 >5PAL-A nrPDB Length = 109 Score = 57.0 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 3/84 (3%) Query: 47 DFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL---STTSRGTLEEKLSW 103 D+ + + G + +F + DKD +GFI EE VL S R + + Sbjct: 25 DYKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKA 84 Query: 104 AFELYDLNHDGYITFDEMLTIVAS 127 D +HDG I DE +VA Sbjct: 85 LLAAGDSDHDGKIGADEFAKMVAQ 108 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 39/96 (40%), Gaps = 11/96 (11%) Query: 78 GFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 G ++ F ++ +G + ++ FE+ D + G+I +E+ ++ + G + Sbjct: 22 GTFDYKRFFHLVGL--KGKTDAQVKEVFEILDKDQSGFIEEEELKGVL-KGFSAHGRDLN 78 Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 E K + D + DG I DEF + Sbjct: 79 DTE--------TKALLAAGDSDHDGKIGADEFAKMV 106 >2N7L-C nrPDB Length = 141 Score = 57.0 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 36/101 (35%), Gaps = 5/101 (4%) Query: 41 GQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDK----DNNGFIHFEEFITVLSTTSRGT 96 G + R IYK + E+ N FD +G I +E V+ + Sbjct: 9 GLVPRGSMDDIYKAAVEQLT-EEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNP 67 Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 E+L + D + G + FDE L ++ K + Sbjct: 68 TPEELQEMIDEVDEDGSGTVDFDEFLVMMVRXMKDDSENLY 108 Score = 32.7 bits (73), Expect = 0.086, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 34/79 (43%), Gaps = 13/79 (16%) Query: 98 EEKLSWAFELYDLNH-DGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 + + AF+++ L DG I+ E+ ++ +M+G T ++++ + Sbjct: 32 KNEFKAAFDIFVLGAEDGSISTKELGKVM----RMLGQNPTP--------EELQEMIDEV 79 Query: 157 DKNEDGYITLDEFREGSKV 175 D++ G + DEF Sbjct: 80 DEDGSGTVDFDEFLVMMVR 98 >5Z1Q-A nrPDB Length = 95 Score = 56.6 bits (135), Expect = 7e-09, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 27/70 (38%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 + F +FD + G I + E + + ++ YD +GYI FD+ Sbjct: 25 QKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDD 84 Query: 121 MLTIVASVYK 130 L I+ K Sbjct: 85 FLDIMTEKIK 94 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 34/85 (40%), Gaps = 12/85 (14%) Query: 89 LSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMR 148 + ++++ AF+L+D N G I + E+ + ++ + Sbjct: 17 VRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALG------------FDVKKPE 64 Query: 149 VKKIFKLMDKNEDGYITLDEFREGS 173 + ++ D+ +GYI D+F + Sbjct: 65 ILELMNEYDREGNGYIGFDDFLDIM 89 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 12/79 (15%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDN 76 ++ + ++EI++ F + +G + + + F + L +D++ Sbjct: 19 QELSEEQKQEIKEAFDLFDTN-KTGSIDYHELKVAMRALG-FDVKKPEILELMNEYDREG 76 Query: 77 NGFIHFEEFITVLSTTSRG 95 NG+I F++F+ +++ + Sbjct: 77 NGYIGFDDFLDIMTEKIKN 95 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 6/57 (10%) Query: 137 TLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK------VDPSIIGALNLYD 187 E + +K+ F L D N+ G I E + + P I+ +N YD Sbjct: 17 VRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYD 73 >4WPX-A nrPDB Length = 177 Score = 56.2 bits (134), Expect = 8e-09, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 28/87 (32%) Query: 42 QLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKL 101 Q + P D F +FD D G I ++ V + + Sbjct: 90 QFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVCQQVGNNIPDADI 149 Query: 102 SWAFELYDLNHDGYITFDEMLTIVASV 128 E +D N G + DE L ++ S Sbjct: 150 QAMIEEFDSNGKGGVDEDEFLRLMMSK 176 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 26/166 (15%), Positives = 48/166 (28%), Gaps = 61/166 (36%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTS--------------------------- 93 + + F +FD + +G + +EEF VL Sbjct: 24 QKTRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRPANWPHDQE 83 Query: 94 ----------------------RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 + ++L AF L+D++ G IT D++ + V Sbjct: 84 CPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVCQQVGN- 142 Query: 132 MGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDP 177 P+ ++ + + D N G + DEF Sbjct: 143 -----------NIPDADIQAMIEEFDSNGKGGVDEDEFLRLMMSKK 177 Score = 35.8 bits (81), Expect = 0.012, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFE 83 R E+++ + F D G + +D K+ +Q P+ + FD + G + + Sbjct: 110 RDELRRAFRLFDVDGK-GMITEDDLRKVCQQVG-NNIPDADIQAMIEEFDSNGKGGVDED 167 Query: 84 EFITVLST 91 EF+ ++ + Sbjct: 168 EFLRLMMS 175 >1S36-A nrPDB Length = 195 Score = 56.2 bits (134), Expect = 9e-09, Method: Composition-based stats. Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 14/129 (10%) Query: 6 SKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSG---QLAREDFVKIYKQFF-----P 57 SK S D L+ + +R Q + F R C ++A F+ +KQ Sbjct: 44 SKASDDICAKLEATPEQTKRH-QVCVEAFFRGCGMEYGKEIAFPQFLDGFKQLATSELKK 102 Query: 58 FGSPEDFA-----NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNH 112 + E + +F +FDKD +G I +E+ + +E F DL++ Sbjct: 103 WARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDLDN 162 Query: 113 DGYITFDEM 121 G + DEM Sbjct: 163 SGDLDVDEM 171 Score = 42.7 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 40/115 (34%), Gaps = 11/115 (9%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEK----------LSWAFELYDLNHDGY 115 H+F D + NG I +E ++ S LE + F + + Sbjct: 23 KHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCGMEYGKE 82 Query: 116 ITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 I F + L + NE +F + DK+ G ITLDE++ Sbjct: 83 IAFPQFLDGFKQLATSELKKWARNEP-TLIREWGDAVFDIFDKDGSGTITLDEWK 136 Score = 27.7 bits (60), Expect = 3.3, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 16/30 (53%) Query: 147 MRVKKIFKLMDKNEDGYITLDEFREGSKVD 176 R K +F +D N +G ITLDE + D Sbjct: 20 KRHKHMFDFLDINGNGKITLDEIVSKASDD 49 >4MVF-A nrPDB Length = 506 Score = 56.2 bits (134), Expect = 9e-09, Method: Composition-based stats. Identities = 20/144 (13%), Positives = 42/144 (29%), Gaps = 46/144 (31%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWA----------------------- 104 +F D DN+G + +E + L + + Sbjct: 365 IFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLAATID 424 Query: 105 -------------FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKK 151 F+ +D++ +G I+ +E+ I + + + + Sbjct: 425 KQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGR----------DDIENPLIDKAIDS 474 Query: 152 IFKLMDKNEDGYITLDEFREGSKV 175 + + +D N DG I EF Sbjct: 475 LLQEVDLNGDGEIDFHEFMLMMSK 498 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 35/91 (38%), Gaps = 1/91 (1%) Query: 3 AKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFF-PFGSP 61 A D L + ++E+ F +G+++ E+ +I+ + Sbjct: 409 ASGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLI 468 Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 + + L D + +G I F EF+ ++S Sbjct: 469 DKAIDSLLQEVDLNGDGEIDFHEFMLMMSKL 499 Score = 30.8 bits (68), Expect = 0.41, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 30/81 (37%), Gaps = 12/81 (14%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE 160 L F D+++ G ++ E+L K +G + + ++ + +D N Sbjct: 362 LRNIFIALDVDNSGTLSSQEILD----GLKKIGYQKIPPD--------IHQVLRDIDSNA 409 Query: 161 DGYITLDEFREGSKVDPSIIG 181 G I +F + + + Sbjct: 410 SGQIHYTDFLAATIDKQTYLK 430 >5OTJ-D nrPDB Length = 110 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 D +F FD + +G I E L T T +++ D + DG+I F+E + Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLGS-TSADEVQRMMAEIDTDGDGFIDFNEFI 61 Query: 123 TIVAS 127 + + Sbjct: 62 SFCNA 66 Score = 55.4 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 36/83 (43%), Gaps = 13/83 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + + F+ +D N DG I+ E+ + ++ +T V+++ +D Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLG-------------STSADEVQRMMAEIDT 49 Query: 159 NEDGYITLDEFREGSKVDPSIIG 181 + DG+I +EF +P ++ Sbjct: 50 DGDGFIDFNEFISFCNANPGLMK 72 >1JF0-A nrPDB Length = 195 Score = 55.4 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 30/61 (49%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 ++ + +F +FDKD +G I +E+ + EE F+ DL++ G + DE Sbjct: 111 IREWGDAVFDIFDKDGSGTITLDEWKAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDE 170 Query: 121 M 121 M Sbjct: 171 M 171 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 40/115 (34%), Gaps = 11/115 (9%) Query: 66 NHLFTVFDKDNNGFIHFEEFIT-----VLSTTSRGTLEEK-----LSWAFELYDLNHDGY 115 +F D + NG I +E ++ + + + + F L + Sbjct: 23 KFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCVEAFFRGCGLEYGKE 82 Query: 116 ITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 F E L ++ + NE +F + DK+ G ITLDE++ Sbjct: 83 TKFPEFLEGWKNLANADLAKWARNEP-TLIREWGDAVFDIFDKDGSGTITLDEWK 136 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 23/54 (42%), Gaps = 2/54 (3%) Query: 31 HKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE 84 F +D SG + +++ K Y + E+ F D DN+G + +E Sbjct: 119 FDIFDKD-GSGTITLDEW-KAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDE 170 Score = 26.9 bits (58), Expect = 5.0, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 20/49 (40%), Gaps = 3/49 (6%) Query: 131 MMGSMVTLNEDEATPEMRVKK---IFKLMDKNEDGYITLDEFREGSKVD 176 M + + +K+ +F +D N +G ITLDE + D Sbjct: 1 MASKYAVKLQTDFDNPKWIKRHKFMFDYLDINGNGQITLDEIVSKASDD 49 >1ZMZ-A nrPDB Length = 98 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 24/69 (34%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 + F +FD D G I +E + +E++ D G + F + Sbjct: 29 QKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGD 88 Query: 121 MLTIVASVY 129 LT++ Sbjct: 89 FLTVMTQKM 97 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 + T ++EI++ F D +G + ++ + E + + DK+ Sbjct: 24 ELTEEQKQEIREAFDLFDAD-GTGTIDVKELKVAMRALGFEPKKE-EIKKMISEIDKEGT 81 Query: 78 GFIHFEEFITVL 89 G ++F +F+TV+ Sbjct: 82 GKMNFGDFLTVM 93 Score = 28.1 bits (61), Expect = 2.1, Method: Composition-based stats. Identities = 8/55 (14%), Positives = 17/55 (30%) Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 + M E + +++ F L D + G I + E + + Sbjct: 5 FKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRA 59 >2JOJ-A nrPDB Length = 77 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 27/70 (38%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 + F +FD + G I + E + + ++ YD +GYI FD+ Sbjct: 5 QKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDD 64 Query: 121 MLTIVASVYK 130 L I+ K Sbjct: 65 FLDIMTEKIK 74 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 33/76 (43%), Gaps = 12/76 (15%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 ++++ AF+L+D N G I + E+ + ++ + + ++ D Sbjct: 6 KQEIKEAFDLFDTNKTGSIDYHELKVAMRALG------------FDVKKPEILELMNEYD 53 Query: 158 KNEDGYITLDEFREGS 173 + +GYI D+F + Sbjct: 54 REGNGYIGFDDFLDIM 69 Score = 35.0 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 34/77 (44%), Gaps = 2/77 (2%) Query: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 + ++EI++ F + +G + + + F + L +D++ NG Sbjct: 1 LSEEQKQEIKEAFDLFDTN-KTGSIDYHELKVAMRALG-FDVKKPEILELMNEYDREGNG 58 Query: 79 FIHFEEFITVLSTTSRG 95 +I F++F+ +++ + Sbjct: 59 YIGFDDFLDIMTEKIKN 75 Score = 26.9 bits (58), Expect = 5.6, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 21/48 (43%), Gaps = 6/48 (12%) Query: 146 EMRVKKIFKLMDKNEDGYITLDEFREGSK------VDPSIIGALNLYD 187 + +K+ F L D N+ G I E + + P I+ +N YD Sbjct: 6 KQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYD 53 >3AAJ-A nrPDB Length = 167 Score = 53.9 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 24/148 (16%), Positives = 48/148 (32%), Gaps = 20/148 (13%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 SG ++ + + + ++FD++N ++F EF V Sbjct: 18 SGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYI------T 71 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 F YD ++ G I +E+ ++ + + + D+ Sbjct: 72 DWQNVFRTYDRDNSGMIDKNELKQALSGYR--------------LSDQFHDILIRKFDRQ 117 Query: 160 EDGYITLDEFREGSKVDPSIIGALNLYD 187 G I D+F +G V + YD Sbjct: 118 GRGQIAFDDFIQGCIVLQRLTDIFRRYD 145 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 48/103 (46%), Gaps = 12/103 (11%) Query: 28 QQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFIT 87 Q + + RD SG + + + + + + F + L FD+ G I F++FI Sbjct: 74 QNVFRTYDRDN-SGMIDKNELKQ---ALSGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQ 129 Query: 88 VLSTTSRGTLEEKLSWAFELYDLNHDGYI--TFDEMLTIVASV 128 ++L+ F YD + DG+I ++++ L++V S+ Sbjct: 130 GCIVL------QRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 166 >4GJF-A nrPDB Length = 89 Score = 53.5 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Query: 14 TCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 ++Q T + E + F++ G ++ ++ K+ + +PE+ + D Sbjct: 7 AAVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMI-DEVD 65 Query: 74 KDNNGFIHFEEFITVL 89 +D +G + F+EF+ ++ Sbjct: 66 EDGSGTVDFDEFLVMM 81 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 28/73 (38%), Gaps = 4/73 (5%) Query: 62 EDFANHLFTVFDK----DNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYIT 117 E+ N FD +G I +E V+ + E+L + D + G + Sbjct: 14 EEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVD 73 Query: 118 FDEMLTIVASVYK 130 FDE L ++ K Sbjct: 74 FDEFLVMMVRCMK 86 Score = 30.4 bits (67), Expect = 0.45, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 26/63 (41%), Gaps = 12/63 (19%) Query: 113 DGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 DG I+ E+ ++ +M+G T ++++ +D++ G + DEF Sbjct: 33 DGCISTKELGKVM----RMLGQNPTP--------EELQEMIDEVDEDGSGTVDFDEFLVM 80 Query: 173 SKV 175 Sbjct: 81 MVR 83 >2LVK-A nrPDB Length = 77 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 D +F FD + +G I E L T T +++ D + DG+I F+E + Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGS-TSADEVQRMMAEIDTDGDGFIDFNEFI 60 Query: 123 TIVAS 127 + + Sbjct: 61 SFCNA 65 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 36/83 (43%), Gaps = 13/83 (15%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + + F+ +D N DG I+ E+ + ++ +T V+++ +D Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLG-------------STSADEVQRMMAEIDT 48 Query: 159 NEDGYITLDEFREGSKVDPSIIG 181 + DG+I +EF +P ++ Sbjct: 49 DGDGFIDFNEFISFCNANPGLMK 71 >3FWC-A nrPDB Length = 161 Score = 52.7 bits (125), Expect = 8e-08, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 33/80 (41%) Query: 46 EDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAF 105 +DF + + P D F +FD D+ G I + V +E+L Sbjct: 79 DDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMI 138 Query: 106 ELYDLNHDGYITFDEMLTIV 125 E +DL+ DG I +E + I Sbjct: 139 EEFDLDGDGEINENEFIAIC 158 Score = 52.7 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 20/131 (15%), Positives = 44/131 (33%), Gaps = 11/131 (8%) Query: 44 AREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSW 103 R + F++FD +N+GF+ + E + + ++ Sbjct: 4 NRSSLQSGPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILD 63 Query: 104 AFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGY 163 + YD + +D+ ++ P +K+ F+L D + G Sbjct: 64 LIDEYDSEGRHLMKYDDFYIVMGEKILKR-----------DPLDEIKRAFQLFDDDHTGK 112 Query: 164 ITLDEFREGSK 174 I++ R +K Sbjct: 113 ISIKNLRRVAK 123 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 25 REIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE 84 EI++ + F D +G+++ ++ ++ K+ + E+ + FD D +G I+ E Sbjct: 96 DEIKRAFQLFDDDH-TGKISIKNLRRVAKELGETLTDEEL-RAMIEEFDLDGDGEINENE 153 Query: 85 FITVLST 91 FI + + Sbjct: 154 FIAICTD 160 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 20/51 (39%) Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 ++ + S +E + + + F L D N DG++ E + K Sbjct: 1 MSKNRSSLQSGPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKA 51 >5XND-A nrPDB Length = 114 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 32/81 (39%), Gaps = 3/81 (3%) Query: 49 VKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWAF 105 K +K G D F + D+D +GFI EE F+ +R + + Sbjct: 33 KKFFKACGLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFL 92 Query: 106 ELYDLNHDGYITFDEMLTIVA 126 + D + DG I DE ++ Sbjct: 93 KAGDSDGDGKIGIDEFAAMIK 113 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 38/97 (39%), Gaps = 11/97 (11%) Query: 78 GFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 G ++F + + T +++ AF + D + G+I +E+ + + ++ Sbjct: 28 GSFDHKKFFKACGLSGKST--DEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARAL-- 83 Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 + K K D + DG I +DEF K Sbjct: 84 -------SDAETKAFLKAGDSDGDGKIGIDEFAAMIK 113 Score = 28.1 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 19/58 (32%), Gaps = 2/58 (3%) Query: 35 LRDCPSGQLAREDFVKIYKQF--FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLS 90 + SG + E+ + F + D D +G I +EF ++ Sbjct: 56 IDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDGDGKIGIDEFAAMIK 113 >2OPO-A nrPDB Length = 86 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 +F FD + +G I E L T T +E + D + DG+I+FDE Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLGSVTPDE-VRRMMAEIDTDGDGFISFDEFTDFA 72 Query: 126 ASVYKMMG 133 + ++ Sbjct: 73 RANRGLVK 80 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 38/83 (45%), Gaps = 13/83 (15%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 F+ +D N DG I+ E+ + ++ + V+++ +D + D Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLG-------------SVTPDEVRRMMAEIDTDGD 60 Query: 162 GYITLDEFREGSKVDPSIIGALN 184 G+I+ DEF + ++ + ++ ++ Sbjct: 61 GFISFDEFTDFARANRGLVKDVS 83 Score = 35.4 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 27/74 (36%), Gaps = 3/74 (4%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN 77 + T D + ++ K F + G+++ + K D + D D + Sbjct: 4 EDTPQDIADRERIFKRFDTN-GDGKISSSELGDALKTLG--SVTPDEVRRMMAEIDTDGD 60 Query: 78 GFIHFEEFITVLST 91 GFI F+EF Sbjct: 61 GFISFDEFTDFARA 74 Score = 30.0 bits (66), Expect = 0.64, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 17/35 (48%), Gaps = 2/35 (5%) Query: 142 EATPEMRVKK--IFKLMDKNEDGYITLDEFREGSK 174 E TP+ + IFK D N DG I+ E + K Sbjct: 4 EDTPQDIADRERIFKRFDTNGDGKISSSELGDALK 38 >3KPX-A nrPDB Length = 198 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 28/56 (50%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 +F +FDKD +G I +E+ T + +E F+ DL++ G + DEM Sbjct: 119 EAVFDIFDKDGSGSISLDEWKTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEM 174 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 32/179 (17%), Positives = 61/179 (34%), Gaps = 39/179 (21%) Query: 15 CLKQSTYFDRREIQQWHK---GFLRDCPSGQLAREDFV-----KIYKQFFPFGSP----E 62 +K T F+ + HK FL +G++ ++ V I + + + Sbjct: 9 AVKLKTNFEDPKWVNRHKFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQ 68 Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKL-------------SWAFELYD 109 + F D + F F+ ++ + KL F+++D Sbjct: 69 EAVEAFFKKIGLDYGKEVEFPAFVNGWKELAKH--DLKLWSQNKKSLIRNWGEAVFDIFD 126 Query: 110 LNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE 168 + G I+ DE +K G + + + E K FK D + G + +DE Sbjct: 127 KDGSGSISLDE--------WKTYGGISGICPSDEDAE----KTFKHCDLDNSGKLDVDE 173 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 45/115 (39%), Gaps = 11/115 (9%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTT---------SRGTLEEK-LSWAFELYDLNHDGY 115 +F D + NG I +E ++ S ++ ++ + F+ L++ Sbjct: 26 KFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYGKE 85 Query: 116 ITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + F + + K + ++ + +F + DK+ G I+LDE++ Sbjct: 86 VEFPAFVNGWKELAK-HDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEWK 139 Score = 26.5 bits (57), Expect = 6.2, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 14/25 (56%) Query: 152 IFKLMDKNEDGYITLDEFREGSKVD 176 +F +D N +G ITLDE + D Sbjct: 28 MFNFLDINGNGKITLDEIVSKASDD 52 >1S6J-A nrPDB Length = 87 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 25/57 (43%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 LF + D DN+G I F+E L +E ++ + D++ G I + E Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEF 81 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 29/73 (39%), Gaps = 12/73 (16%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE 160 L F++ D ++ G ITFDE+ + V + E +K + D ++ Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLKRVGSEL------------MESEIKDLMDAADIDK 72 Query: 161 DGYITLDEFREGS 173 G I EF + Sbjct: 73 SGTIDYGEFIAAT 85 Score = 35.8 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 31/85 (36%), Gaps = 2/85 (2%) Query: 4 KTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPED 63 + + DD ++ + + +++ K D SG + ++ K+ E Sbjct: 2 SSGHIDDDDKHMAERLSEEEIGGLKELFKMIDTDN-SGTITFDELKDGLKRVGSELM-ES 59 Query: 64 FANHLFTVFDKDNNGFIHFEEFITV 88 L D D +G I + EFI Sbjct: 60 EIKDLMDAADIDKSGTIDYGEFIAA 84 Score = 29.6 bits (65), Expect = 0.82, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 19/27 (70%) Query: 149 VKKIFKLMDKNEDGYITLDEFREGSKV 175 +K++FK++D + G IT DE ++G K Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLKR 51 >1C7W-A nrPDB Length = 81 Score = 52.0 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 11/88 (12%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 R EE++ AF+++D N DG I FDE I+ V +E + V++ Sbjct: 3 RQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVG-----------EEPLTDAEVEEAM 51 Query: 154 KLMDKNEDGYITLDEFREGSKVDPSIIG 181 K D++ +G I + EF + K + + Sbjct: 52 KEADEDGNGVIDIPEFMDLIKKSKNALK 79 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITF 118 E+ F VFD + +G I F+EF ++ + ++ A + D + +G I Sbjct: 5 DDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDI 64 Query: 119 DEMLTIVAS 127 E + ++ Sbjct: 65 PEFMDLIKK 73 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 29/76 (38%), Gaps = 1/76 (1%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 D EI + K F + G + ++F I ++ + D+D NG I Sbjct: 6 DEEEILRAFKVFDAN-GDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDI 64 Query: 83 EEFITVLSTTSRGTLE 98 EF+ ++ + E Sbjct: 65 PEFMDLIKKSKNALKE 80 >3PM8-A nrPDB Length = 197 Score = 52.0 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 20/146 (13%), Positives = 42/146 (28%), Gaps = 46/146 (31%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWA----------------------- 104 +F D DN+G + +E + L + + Sbjct: 62 IFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLAATID 121 Query: 105 -------------FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKK 151 F+ +D++ +G I+ +E+ I + + + + Sbjct: 122 KQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGR----------DDIENPLIDKAIDS 171 Query: 152 IFKLMDKNEDGYITLDEFREGSKVDP 177 + + +D N DG I EF Sbjct: 172 LLQEVDLNGDGEIDFHEFMLMMSKKK 197 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 35/89 (39%), Gaps = 1/89 (1%) Query: 3 AKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFF-PFGSP 61 A D L + ++E+ F +G+++ E+ +I+ + Sbjct: 106 ASGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLI 165 Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLS 90 + + L D + +G I F EF+ ++S Sbjct: 166 DKAIDSLLQEVDLNGDGEIDFHEFMLMMS 194 Score = 28.5 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 30/81 (37%), Gaps = 12/81 (14%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE 160 L F D+++ G ++ E+L K +G + + ++ + +D N Sbjct: 59 LRNIFIALDVDNSGTLSSQEILD----GLKKIGYQKIPPD--------IHQVLRDIDSNA 106 Query: 161 DGYITLDEFREGSKVDPSIIG 181 G I +F + + + Sbjct: 107 SGQIHYTDFLAATIDKQTYLK 127 >2HPS-A nrPDB Length = 186 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 24/55 (43%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 ++ D D +G++ EF L ++K F D N +G I+ DE L Sbjct: 107 MYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFL 161 Score = 35.0 bits (79), Expect = 0.021, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 50/151 (33%), Gaps = 27/151 (17%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGS-----PEDFANHLFTVFDKDNNG---FIHFEEF- 85 + G ++RED+ I + E+ V D+ I EE Sbjct: 23 VDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQLGLAPGVRISVEEAA 82 Query: 86 ITVLSTTSRGTLEEKLSWAFEL------YDLNHDGYITFDEMLTIVASVYKMMGSMVTLN 139 + + + EEK + D + DGY++ E + +V Sbjct: 83 VNATDSLLKMKGEEKAMAVIQSLIMYDCIDTDKDGYVSLPEFKAFLQAVGP--------- 133 Query: 140 EDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + + F +D N++G I+ DEF Sbjct: 134 ---DLTDDKAITCFNTLDFNKNGQISRDEFL 161 Score = 33.5 bits (75), Expect = 0.054, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 27/66 (40%), Gaps = 1/66 (1%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 G ++ +F + P + + F D + NG I +EF+ ++ G E Sbjct: 116 DGYVSLPEFKAFLQAVGPDLTDDKAIT-CFNTLDFNKNGQISRDEFLVTVNDFLFGLEET 174 Query: 100 KLSWAF 105 L+ AF Sbjct: 175 ALANAF 180 Score = 31.2 bits (69), Expect = 0.30, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 50/136 (36%), Gaps = 22/136 (16%) Query: 56 FPFGSPEDFANHLFTV------FDKDNNGFIHFE--EFITVLSTTSRGTLEEKLSWAFEL 107 P + + A HL + D +GFI E E I V EK + Sbjct: 1 MPEITESERAYHLRKMKTRMQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQE 60 Query: 108 Y--DLNHDG-----YITFDEML-TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 + + G I+ +E S+ KM G + ++ ++ +D + Sbjct: 61 FLRVADQLGLAPGVRISVEEAAVNATDSLLKMKGEEKAMAVIQSLI------MYDCIDTD 114 Query: 160 EDGYITLDEFREGSKV 175 +DGY++L EF+ + Sbjct: 115 KDGYVSLPEFKAFLQA 130 >1M39-A nrPDB Length = 89 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 33/86 (38%) Query: 43 LAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS 102 + DF+ + Q ++ F +FD D G I F+ V +E+L Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQ 60 Query: 103 WAFELYDLNHDGYITFDEMLTIVASV 128 + D + DG ++ E L I+ Sbjct: 61 EMIDEADRDGDGEVSEQEFLRIMKKT 86 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 44/96 (45%), Gaps = 13/96 (13%) Query: 81 HFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLN 139 +F +F+TV++ S +E++ AF+L+D + G I+F + + + Sbjct: 2 NFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELG---------- 51 Query: 140 EDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 E + ++++ D++ DG ++ EF K Sbjct: 52 --ENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKK 85 Score = 33.1 bits (74), Expect = 0.074, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Query: 16 LKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKD 75 K S + EI + K F D +G+++ ++ ++ K+ + E+ + D+D Sbjct: 12 QKMSEKDTKEEILKAFKLFDDD-ETGKISFKNLKRVAKELGENLTDEELQEMI-DEADRD 69 Query: 76 NNGFIHFEEFITVLSTTS 93 +G + +EF+ ++ TS Sbjct: 70 GDGEVSEQEFLRIMKKTS 87 >1W7I-B nrPDB Length = 151 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 39/115 (33%), Gaps = 11/115 (9%) Query: 58 FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFE--LYDLNHDGY 115 + F +FD+ +G I + + V+ + ++ D Sbjct: 5 NKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRR 64 Query: 116 ITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + F+ L ++ +V K G + E F++ DK +G + E R Sbjct: 65 VDFETFLPMLQAVAKNRGQGTYEDYLEG---------FRVFDKEGNGKVMGAELR 110 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 40/90 (44%), Gaps = 3/90 (3%) Query: 36 RDCPSGQLAREDFVKIYKQFFPFGSPEDFANHL--FTVFDKDNNGFIHFEEFITVLSTTS 93 + S ++ E F+ + + + ++L F VFDK+ NG + E VL+T Sbjct: 58 DELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLG 117 Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 EE++ ++ + +G I ++ L Sbjct: 118 EKMTEEEVETVLAGHE-DSNGCINYEAFLK 146 Score = 33.1 bits (74), Expect = 0.068, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 52/151 (34%), Gaps = 20/151 (13%) Query: 25 REIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHL-FTVFDKDNNGFIHFE 83 E ++ + F R G++ + + + + L D+ + + FE Sbjct: 10 EEFKEAFELFDRV-GDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFE 68 Query: 84 EFITVLSTT----SRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLN 139 F+ +L +GT E+ L F ++D +G + E+ V Sbjct: 69 TFLPMLQAVAKNRGQGTYEDYLE-GFRVFDKEGNGKVMGAEL------------RHVLTT 115 Query: 140 EDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 E E V+ + ++ +G I + F Sbjct: 116 LGEKMTEEEVETVLA-GHEDSNGCINYEAFL 145 >1YX7-A nrPDB Length = 83 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 6/77 (7%) Query: 96 TLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKL 155 ++ +L AF+ D N DGY+T E+ T + ++ + + K+ K+ Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTL------DAYKALSKDKVKEASAKLIKM 57 Query: 156 MDKNEDGYITLDEFREG 172 DKN DG I+ +EF Sbjct: 58 ADKNSDGKISKEEFLNA 74 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 31/76 (40%), Gaps = 6/76 (7%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTS--RGTLEEKLSWA----FELYDLNHD 113 + F D + +G++ E T + T + ++K+ A ++ D N D Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSD 63 Query: 114 GYITFDEMLTIVASVY 129 G I+ +E L A + Sbjct: 64 GKISKEEFLNANAELL 79 Score = 26.5 bits (57), Expect = 7.1, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 148 RVKKIFKLMDKNEDGYITLDEFREGS 173 ++ FK +D N DGY+T E + Sbjct: 8 ELEAAFKKLDANGDGYVTALELQTFM 33 >2K7C-A nrPDB Length = 72 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 30/77 (38%), Gaps = 11/77 (14%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 ++L AF +D N DG I+ E+ + + +++I + +D Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGH-----------RDIEEIIRDVDL 55 Query: 159 NEDGYITLDEFREGSKV 175 N DG + +EF Sbjct: 56 NGDGRVDFEEFVRMMSR 72 Score = 49.7 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 23/66 (34%), Gaps = 1/66 (1%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLS-TTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 F FD + +G I E + + DLN DG + F+E Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEF 66 Query: 122 LTIVAS 127 + +++ Sbjct: 67 VRMMSR 72 Score = 39.6 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 29/67 (43%), Gaps = 1/67 (1%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFE 83 +E++ + F + G+++ + + ++ + D + +G + FE Sbjct: 6 VKELRDAFREFDTN-GDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFE 64 Query: 84 EFITVLS 90 EF+ ++S Sbjct: 65 EFVRMMS 71 Score = 33.9 bits (76), Expect = 0.045, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 15/34 (44%) Query: 142 EATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 + ++ F+ D N DG I+ E RE + Sbjct: 2 DMIGVKELRDAFREFDTNGDGEISTSELREAMRK 35 >1H4B-A nrPDB Length = 84 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 25/64 (39%), Gaps = 1/64 (1%) Query: 58 FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYIT 117 + +F FD + +G I E L T T +E + D + DG+I+ Sbjct: 4 HPQDKAERERIFKRFDANGDGKISAAELGEALKTLGSITPDE-VKHMMAEIDTDGDGFIS 62 Query: 118 FDEM 121 F E Sbjct: 63 FQEF 66 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 35/84 (41%), Gaps = 13/84 (15%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 + + F+ +D N DG I+ E+ + ++ + VK + +D Sbjct: 8 KAERERIFKRFDANGDGKISAAELGEALKTLG-------------SITPDEVKHMMAEID 54 Query: 158 KNEDGYITLDEFREGSKVDPSIIG 181 + DG+I+ EF + + + ++ Sbjct: 55 TDGDGFISFQEFTDFGRANRGLLK 78 >5VE9-A nrPDB Length = 91 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Query: 39 PSGQLAREDFVKIYKQFFPF-GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTL 97 P G +A DF K++ + + F DKD +G I +EFI + + T Sbjct: 2 PGGHMANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTT 61 Query: 98 EEKLSWAFELYDLNHDGYITFDEM 121 + +++ +++D + DGYI + E Sbjct: 62 KLEMTAVADIFDRDGDGYIDYYEF 85 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFE 83 + + + + +D G++ R++F+ F + + + +FD+D +G+I + Sbjct: 26 KSRVMDFFRRIDKD-QDGKITRQEFIDGILA-SKFPTTKLEMTAVADIFDRDGDGYIDYY 83 Query: 84 EFITVLST 91 EF+ L Sbjct: 84 EFVAALHP 91 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 30/77 (38%), Gaps = 14/77 (18%) Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLT-IVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 + ++ F D + DG IT E + I+AS + +T D Sbjct: 23 NHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVAD------------ 70 Query: 154 KLMDKNEDGYITLDEFR 170 + D++ DGYI EF Sbjct: 71 -IFDRDGDGYIDYYEFV 86 Score = 32.7 bits (73), Expect = 0.090, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 17/30 (56%) Query: 148 RVKKIFKLMDKNEDGYITLDEFREGSKVDP 177 RV F+ +DK++DG IT EF +G Sbjct: 28 RVMDFFRRIDKDQDGKITRQEFIDGILASK 57 >4P5W-A nrPDB Length = 411 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 35/191 (18%), Positives = 63/191 (32%), Gaps = 28/191 (14%) Query: 9 SKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQ--LAREDFVKIYKQFFPFGSPEDF-A 65 + + + + D E++ + +G+ ++ DFV Y F P Sbjct: 21 TSEAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTV 80 Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 L V D+ +G I F+EF+ S + AF+L+D G +TF+++ + Sbjct: 81 ELLSGVVDQTKDGLISFQEFVAFESVLCA--PDALFMVAFQLFDKAGKGEVTFEDVKQVF 138 Query: 126 ASV-------------------YKMMGSMVTLNEDE----ATPEMRVKKIFKLMDKNEDG 162 K +T E K+ F D G Sbjct: 139 GQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTG 198 Query: 163 YITLDEFREGS 173 +T +FR+ Sbjct: 199 RVTAIDFRDIM 209 >3MSE-B nrPDB Length = 180 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 15/111 (13%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 + N LF D ++NG + E TVL++ + ++ + D+N G IT+ E Sbjct: 39 KYINELFYKLDTNHNGSLSHREIYTVLASVGIKKWD--INRILQALDINDRGNITYTEF- 95 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 +A Y+ T +K F +DK+EDGYI+ + Sbjct: 96 --MAGCYRWKNIEST----------FLKAAFNKIDKDEDGYISKSDIVSLV 134 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 50/141 (35%), Gaps = 10/141 (7%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 L +G L+ + IY G + N + D ++ G I + EF+ + Sbjct: 48 LDTNHNGSLSHRE---IYTVLASVGIKKWDINRILQALDINDRGNITYTEFMAGC-YRWK 103 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 L AF D + DGYI+ +++++V + + + + + Sbjct: 104 NIESTFLKAAFNKIDKDEDGYISKSDIVSLVHDKVLDNNDIDNFFLSVHSIKKGIPREHI 163 Query: 155 LMDKNEDGYITLDEFREGSKV 175 + I+ EF++ Sbjct: 164 I------NKISFQEFKDYMLS 178 Score = 35.0 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 14/79 (17%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE 160 ++ F D NH+G ++ E+ T++ASV + + +I + +D N+ Sbjct: 41 INELFYKLDTNHNGSLSHREIYTVLASVG--------------IKKWDINRILQALDIND 86 Query: 161 DGYITLDEFREGSKVDPSI 179 G IT EF G +I Sbjct: 87 RGNITYTEFMAGCYRWKNI 105 >6IIE-A nrPDB Length = 93 Score = 50.4 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 43/91 (47%), Gaps = 3/91 (3%) Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 G E+KL + F+LYD + +G + E+ I + +MM L+ D + ++++ K Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKI---ILQMMRVAEYLDWDVSELRPILQEMMK 61 Query: 155 LMDKNEDGYITLDEFREGSKVDPSIIGALNL 185 +D + G ++ E+ ++ L L Sbjct: 62 EIDYDGSGSVSQAEWVRAGATTVPLLVLLGL 92 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 25/71 (35%), Gaps = 9/71 (12%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR---------GTLEEKLSWAFELYD 109 G PED F ++D D NG + E ++ R L L + D Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEID 64 Query: 110 LNHDGYITFDE 120 + G ++ E Sbjct: 65 YDGSGSVSQAE 75 >5XOP-A nrPDB Length = 66 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 29/64 (45%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A LF D + +G + +EE +S E+ L F+ D + DG+I F+E Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKF 61 Query: 125 VASV 128 S+ Sbjct: 62 YGSI 65 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 12/68 (17%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 F+ D+N DG ++++E+ V+ + E ++ IFK +DK+ D Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN------------EQLLQLIFKSIDKDGD 50 Query: 162 GYITLDEF 169 G+I +EF Sbjct: 51 GFIDFEEF 58 Score = 33.9 bits (76), Expect = 0.046, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFI 86 + G ++ E+ VK + E +F DKD +GFI FEEF Sbjct: 9 IDVNGDGAVSYEE-VKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFA 59 Score = 26.2 bits (56), Expect = 8.4, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 16/30 (53%) Query: 150 KKIFKLMDKNEDGYITLDEFREGSKVDPSI 179 + +FK +D N DG ++ +E + +I Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAI 32 >2Q4U-A nrPDB Length = 272 Score = 49.7 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 35/202 (17%), Positives = 71/202 (35%), Gaps = 23/202 (11%) Query: 2 GAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCP---SGQLARED----------- 47 G + + L L+ +QQ K F+ G+L E+ Sbjct: 30 GKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFDGRLQIEELANMILPQEEN 89 Query: 48 FVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTT--------SRGTLEE 99 F+ I+++ P + +F ++ +D D++G+I E L L+E Sbjct: 90 FLLIFRREAPLDNSVEFMK-IWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDE 148 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 +++D N DG + +++ I+A + + + +KIF D + Sbjct: 149 YTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVS 208 Query: 160 EDGYITLDEFREGSKVDPSIIG 181 G + E K ++ Sbjct: 209 RTGALEGPEVDGFVKDMMELVR 230 Score = 49.7 bits (117), Expect = 9e-07, Method: Composition-based stats. Identities = 26/163 (15%), Positives = 61/163 (37%), Gaps = 24/163 (14%) Query: 26 EIQQWHKGFLRDCPSGQLAREDFVKIYKQFF-------PFGSPEDFANHLFTVFDKDNNG 78 E + + + D SG ++ + K F P +++ + + +FDK+ +G Sbjct: 105 EFMKIWRKYDADS-SGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDG 163 Query: 79 FIHFEEFITVLS------------TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 + + +L+ +S+ + F YD++ G + E+ V Sbjct: 164 RLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVK 223 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + +++ ++ + + E + D N+DG I E Sbjct: 224 DMMELVRPSISGGDLDKFREC----LLTHCDMNKDGKIQKSEL 262 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 45/118 (38%), Gaps = 11/118 (9%) Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGT------LEEKLSWA----FELYDLNHDGYI 116 ++ FD D+NG+I +E + +E++ YD DG + Sbjct: 15 QIWQHFDADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFDGRL 74 Query: 117 TFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 +E+ ++ + ++ E + KI++ D + GYI+ E + K Sbjct: 75 QIEELANMILPQ-EENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAELKNFLK 131 Score = 31.9 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 24/73 (32%), Gaps = 2/73 (2%) Query: 106 ELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYIT 165 + +D + +GYI E+ + K + + + + K D DG + Sbjct: 18 QHFDADDNGYIEGKELDDFFRHMLKKLQPKDKIT--DERVQQIKKSFMSAYDATFDGRLQ 75 Query: 166 LDEFREGSKVDPS 178 ++E Sbjct: 76 IEELANMILPQEE 88 >2KQY-A nrPDB Length = 108 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Query: 52 YKQFFPF----GSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWA 104 YK FF D +F + D+D +GFI EE F+ S+++R + Sbjct: 26 YKSFFSTVGLSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAF 85 Query: 105 FELYDLNHDGYITFDEMLTIVAS 127 D + DG I +E ++V + Sbjct: 86 LAAGDTDGDGKIGVEEFQSLVKA 108 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 31/82 (37%), Gaps = 9/82 (10%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 +++ F + D + G+I +E+ + + ++T E K Sbjct: 36 SSKTPDQIKKVFGILDQDKSGFIEEEEL-QLFLKNFSSSARVLTSAE--------TKAFL 86 Query: 154 KLMDKNEDGYITLDEFREGSKV 175 D + DG I ++EF+ K Sbjct: 87 AAGDTDGDGKIGVEEFQSLVKA 108 >1UHK-A nrPDB Length = 191 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 24/56 (42%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 + LF + DKD NG I +E+ E F + D++ G + DEM Sbjct: 112 DALFDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEM 167 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 45/126 (35%), Gaps = 23/126 (18%) Query: 66 NHLFTVFDKDNNGFIHFEEFI-----TVLSTTSRGTLEEKLS-WAFELY----------D 109 H+F D ++NG I +E + V++ + K A E + + Sbjct: 19 KHMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFFGGAGMKYGVE 78 Query: 110 LNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + YI + + +F ++DK+++G ITLDE+ Sbjct: 79 TDWPAYIE-------GWKKLATDELEKYAKNEPTLIRIWGDALFDIVDKDQNGAITLDEW 131 Query: 170 REGSKV 175 + +K Sbjct: 132 KAYTKA 137 Score = 26.5 bits (57), Expect = 7.2, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 32/81 (39%), Gaps = 7/81 (8%) Query: 7 KLSKDDLTCLKQSTYFDRREIQQWHKGF---LRDCPSGQLAREDFVKIYKQFFPFGSPED 63 KL+ D+L ++ + I+ W + +G + +++ K Y + + Sbjct: 90 KLATDELEKYAKN---EPTLIRIWGDALFDIVDKDQNGAITLDEW-KAYTKAAGIIQSSE 145 Query: 64 FANHLFTVFDKDNNGFIHFEE 84 F V D D +G + +E Sbjct: 146 DCEETFRVCDIDESGQLDVDE 166 >1SL8-A nrPDB Length = 191 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 25/56 (44%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 + LF + DKD NG I +E+ + E F + D++ G + DEM Sbjct: 112 DALFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEM 167 Score = 35.8 bits (81), Expect = 0.012, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 49/120 (40%), Gaps = 11/120 (9%) Query: 66 NHLFTVFDKDNNGFIHFEEFI-----TVLSTTSRGTLEEKLS-WAFELYDLNHDG--YIT 117 H+F D ++NG I +E + V++ + K A E + G Y Sbjct: 19 KHMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAF-FGGAGMKYGV 77 Query: 118 FDEMLTIVASVYKMMGSMVTLNEDEATPEMRV--KKIFKLMDKNEDGYITLDEFREGSKV 175 E + ++ + +R+ +F ++DK+++G I+LDE++ +K Sbjct: 78 ETEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEWKAYTKS 137 Score = 26.9 bits (58), Expect = 5.6, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 28/74 (37%), Gaps = 4/74 (5%) Query: 14 TCLKQSTYFDRREIQQWHKGF---LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFT 70 LK+ + I+ W + +G ++ +++ K Y + + F Sbjct: 94 EELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEW-KAYTKSAGIIQSSEDCEETFR 152 Query: 71 VFDKDNNGFIHFEE 84 V D D +G + +E Sbjct: 153 VCDIDESGQLDVDE 166 >2G9B-A nrPDB Length = 263 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 45/108 (41%), Gaps = 12/108 (11%) Query: 70 TVFDKDNNGFIHFEEFITVLSTTSRGTL----EEKLSW----AFELYDLNHDGYITFDEM 121 +D D++GFI EE L + KL+ +L+D N+DG + E Sbjct: 110 RKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE- 168 Query: 122 LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 +A + + + + + K F+L D++ +GYI +E Sbjct: 169 ---MARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 213 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 31/177 (17%), Positives = 58/177 (32%), Gaps = 19/177 (10%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP-----EDFANHLFTVF 72 QS+ + + F D SG L ++ + ++ + Sbjct: 9 QSSLITASQFFEIWLHFDAD-GSGYLEGKELQNLIQELLQARKKAGLELSPEMKTFVDQY 67 Query: 73 DKDNNGFIHFEEFITVLSTTS---------RGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 + ++G I E VL T + E+ + YD +H G+I +E+ Sbjct: 68 GQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 127 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 + + + V D+ + KL D N DG + L E V + + Sbjct: 128 FLKDLLEKANKTV----DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFL 180 Score = 46.2 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 53/131 (40%), Gaps = 16/131 (12%) Query: 25 REIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPE-------DFANHLFTVFDKDNN 77 E + + + D SG + E+ K + ++ + + +FD +N+ Sbjct: 103 EEFMKTWRKYDTDH-SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 161 Query: 78 GFIHFEEFITVLSTTSRGTLE--------EKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 G + E +L L+ ++ + AFELYD + +GYI +E+ ++ + Sbjct: 162 GKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 221 Query: 130 KMMGSMVTLNE 140 + + +N Sbjct: 222 EKNKQELDINN 232 >5B7X-A nrPDB Length = 156 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 45/105 (42%), Gaps = 11/105 (10%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 F +D+D +G I ++ T++ + E++++ + + + + ++ I Sbjct: 15 IRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAIEGE-TFQIEQFELI 73 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 + T E++++K F++ D+++DG I + Sbjct: 74 MER----------EQSKPDTREIKLRKAFEVFDQDKDGKIKASDL 108 Score = 39.6 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 52/144 (36%), Gaps = 14/144 (9%) Query: 33 GFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGF-IHFEEFITVLST 91 F G++ + + + + ED N F + F I E I Sbjct: 20 NFYDRDYDGKIDVKQLGTLIRSLGCAPT-EDEVNSYIKEFAIEGETFQIEQFELIMEREQ 78 Query: 92 TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKK 151 + T E KL AFE++D + DG I ++ + +V + + V+K Sbjct: 79 SKPDTREIKLRKAFEVFDQDKDGKIKASDLAHNLTTVG------------DKMTKEEVEK 126 Query: 152 IFKLMDKNEDGYITLDEFREGSKV 175 +F ++ + I L F + + Sbjct: 127 VFSILGITMESDIDLATFLKLVAL 150 >4NQG-A nrPDB Length = 197 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 25/56 (44%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 + LF + DKD NG + +E+I + F DL+ DG + DEM Sbjct: 117 DALFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDEM 172 Score = 47.0 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 30/177 (16%), Positives = 55/177 (31%), Gaps = 35/177 (19%) Query: 15 CLKQSTYFDRREIQQWHK---GFLRDCPSGQLAREDFVKIYKQFF--PFGSPEDF----- 64 +K T FD + HK FL +GQ+ + V G+ E+ Sbjct: 7 AVKLDTDFDNPKWIARHKHMFNFLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQ 66 Query: 65 --ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS-----------WAFELYDLN 111 F + + + E+I ++ LE F++ D + Sbjct: 67 KCVEDFFGGAGLEYDKDTTWPEYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKD 126 Query: 112 HDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE 168 +G ++ DE + T + + F D + DG + +DE Sbjct: 127 GNGSVSLDEWIQ------------YTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDE 171 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 47/120 (39%), Gaps = 19/120 (15%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTT---SRGTLEEK-------LSWAFE----LYDLN 111 H+F D ++NG I+ E + S G EE+ + F YD + Sbjct: 24 KHMFNFLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVEDFFGGAGLEYDKD 83 Query: 112 HDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 T+ E + + K + N + +F ++DK+ +G ++LDE+ + Sbjct: 84 T----TWPEYIEGWKRLAKTELERHSKN-RVTLIRLWGDALFDIIDKDGNGSVSLDEWIQ 138 >2MA2-A nrPDB Length = 81 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 31/77 (40%), Gaps = 7/77 (9%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 E +F FD D +G I EEF + + AF D N DG I+ +E Sbjct: 11 IEKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLS-------AFGDLDQNQDGCISREE 63 Query: 121 MLTIVASVYKMMGSMVT 137 M++ ++G + Sbjct: 64 MVSYFLRSSSVLGGRMG 80 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 35/86 (40%), Gaps = 19/86 (22%) Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 +E+ + F +D++ DG+I+ +E I + + F + Sbjct: 11 IEKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLS-------------------AFGDL 51 Query: 157 DKNEDGYITLDEFREGSKVDPSIIGA 182 D+N+DG I+ +E S++G Sbjct: 52 DQNQDGCISREEMVSYFLRSSSVLGG 77 >5JOJ-A nrPDB Length = 97 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 +L AF D + +GYI+F+E+ + + L + + D + Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAA--------CLPLPGYRVREITENLMATGDLD 64 Query: 160 EDGYITLDEFR 170 +DG I+ DEF Sbjct: 65 QDGRISFDEFI 75 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 24/66 (36%), Gaps = 4/66 (6%) Query: 64 FANHLFTVFDKDNNGFIHFEE----FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 F D D NG+I F E F + E DL+ DG I+FD Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFD 72 Query: 120 EMLTIV 125 E + I Sbjct: 73 EFIKIF 78 Score = 30.8 bits (68), Expect = 0.37, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 33/90 (36%), Gaps = 4/90 (4%) Query: 20 TYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQF---FPFGSPEDFANHLFTVFDKDN 76 + + E+++ D +G ++ + ++K P + +L D D Sbjct: 7 SDEEMMELREAFAKVDTD-GNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQ 65 Query: 77 NGFIHFEEFITVLSTTSRGTLEEKLSWAFE 106 +G I F+EFI + + + A Sbjct: 66 DGRISFDEFIKIFHGLKSTDVAKTFRKAIN 95 Score = 30.4 bits (67), Expect = 0.50, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 17/31 (54%) Query: 147 MRVKKIFKLMDKNEDGYITLDEFREGSKVDP 177 M +++ F +D + +GYI+ +E + K Sbjct: 12 MELREAFAKVDTDGNGYISFNELNDLFKAAC 42 >5JOL-A nrPDB Length = 82 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 +L AF D + +GYI+F+E+ + + L + + D + Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAA--------CLPLPGYRVREITENLMATGDLD 64 Query: 160 EDGYITLDEFR 170 +DG I+ DEF Sbjct: 65 QDGRISFDEFI 75 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 24/66 (36%), Gaps = 4/66 (6%) Query: 64 FANHLFTVFDKDNNGFIHFEE----FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 F D D NG+I F E F + E DL+ DG I+FD Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFD 72 Query: 120 EMLTIV 125 E + I Sbjct: 73 EFIKIF 78 Score = 30.4 bits (67), Expect = 0.54, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 17/31 (54%) Query: 147 MRVKKIFKLMDKNEDGYITLDEFREGSKVDP 177 M +++ F +D + +GYI+ +E + K Sbjct: 12 MELREAFAKVDTDGNGYISFNELNDLFKAAC 42 Score = 29.6 bits (65), Expect = 0.73, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 30/76 (39%), Gaps = 4/76 (5%) Query: 20 TYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQF---FPFGSPEDFANHLFTVFDKDN 76 + + E+++ D +G ++ + ++K P + +L D D Sbjct: 7 SDEEMMELREAFAKVDTD-GNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQ 65 Query: 77 NGFIHFEEFITVLSTT 92 +G I F+EFI + Sbjct: 66 DGRISFDEFIKIFHGL 81 >1OQP-A nrPDB Length = 77 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 26/69 (37%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 + F +FD DN+G I ++ V EE+L D N D I D Sbjct: 6 DSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDED 65 Query: 120 EMLTIVASV 128 E + I+ Sbjct: 66 EFIRIMKKT 74 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 32/83 (38%), Gaps = 12/83 (14%) Query: 93 SRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKI 152 E++ AF L+D ++ G IT ++ V E E ++++ Sbjct: 3 GERDSREEILKAFRLFDDDNSGTITIKDL------------RRVAKELGENLTEEELQEM 50 Query: 153 FKLMDKNEDGYITLDEFREGSKV 175 D+N+D I DEF K Sbjct: 51 IAEADRNDDNEIDEDEFIRIMKK 73 Score = 31.9 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 R EI + + F D SG + +D ++ K+ + E+ + D++++ I Sbjct: 7 SREEILKAFRLFDDDN-SGTITIKDLRRVAKELGENLT-EEELQEMIAEADRNDDNEIDE 64 Query: 83 EEFITVLSTTS 93 +EFI ++ TS Sbjct: 65 DEFIRIMKKTS 75 >2VRG-A nrPDB Length = 124 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Query: 96 TLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKL 155 E +L + F+++D + + + E+ T + V+K GS E + + + Sbjct: 47 PQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRD 105 Query: 156 MDKNEDGYITLDEFREGSK 174 DKN DGYI EF + + Sbjct: 106 DDKNNDGYIDYAEFAKSLQ 124 Score = 26.9 bits (58), Expect = 4.7, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 25/84 (29%), Gaps = 11/84 (13%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPE-----------DFA 65 K +E+Q + + L + E + Sbjct: 40 KPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINII 99 Query: 66 NHLFTVFDKDNNGFIHFEEFITVL 89 + + DK+N+G+I + EF L Sbjct: 100 DGVLRDDDKNNDGYIDYAEFAKSL 123 >2M7M-A nrPDB Length = 66 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 27/64 (42%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A LF D + +G + +EE +S E+ L F+ D + +G I +E Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKF 61 Query: 125 VASV 128 S+ Sbjct: 62 YGSI 65 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 31/68 (45%), Gaps = 12/68 (17%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 F+ D+N DG ++++E+ V+ + E ++ IFK +D + + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN------------EQLLQLIFKSIDADGN 50 Query: 162 GYITLDEF 169 G I +EF Sbjct: 51 GEIDQNEF 58 Score = 27.7 bits (60), Expect = 3.0, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 19/52 (36%), Gaps = 1/52 (1%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFI 86 + G ++ E+ VK + E +F D D NG I EF Sbjct: 9 IDVNGDGAVSYEE-VKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFA 59 Score = 26.9 bits (58), Expect = 5.5, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 16/30 (53%) Query: 150 KKIFKLMDKNEDGYITLDEFREGSKVDPSI 179 + +FK +D N DG ++ +E + +I Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAI 32 >3LCP-C nrPDB Length = 93 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Query: 96 TLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKL 155 E +L + F+++D + + + E+ T + V+K GS E + + + Sbjct: 16 PQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRD 74 Query: 156 MDKNEDGYITLDEFREGSK 174 DKN DGYI EF + + Sbjct: 75 DDKNNDGYIDYAEFAKSLQ 93 Score = 26.9 bits (58), Expect = 4.8, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 25/84 (29%), Gaps = 11/84 (13%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPE-----------DFA 65 K +E+Q + + L + E + Sbjct: 9 KPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINII 68 Query: 66 NHLFTVFDKDNNGFIHFEEFITVL 89 + + DK+N+G+I + EF L Sbjct: 69 DGVLRDDDKNNDGYIDYAEFAKSL 92 >4YGB-B nrPDB Length = 104 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 37/89 (41%), Gaps = 1/89 (1%) Query: 86 ITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATP 145 I E +L + F+++D + + + E+ T + V+K GS E Sbjct: 17 IEGRHMLEMSPQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDEL 75 Query: 146 EMRVKKIFKLMDKNEDGYITLDEFREGSK 174 + + + DKN DGYI EF + + Sbjct: 76 INIIDGVLRDDDKNNDGYIDYAEFAKSLQ 104 >3J04-B nrPDB Length = 143 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 43/116 (37%), Gaps = 16/116 (13%) Query: 56 FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 F ++F F + D++ +GFI E+ +L++ + +E L G Sbjct: 1 FDQSQIQEFKEA-FNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEGMMSEA----PGP 55 Query: 116 ITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 I F LT+ + PE ++ F D+ G+I D RE Sbjct: 56 INFTMFLTMFGEKL-----------NGTDPEDVIRNAFACFDEEASGFIHEDHLRE 100 Score = 42.7 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 47/107 (43%), Gaps = 1/107 (0%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFE 83 + ++ +G + + P G + F+ ++ + PED + F FD++ +GFIH + Sbjct: 38 KNPTDEYLEGMMSEAP-GPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHED 96 Query: 84 EFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYK 130 +L+T +E++ + ++ G + E I+ K Sbjct: 97 HLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAK 143 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 60/156 (38%), Gaps = 20/156 (12%) Query: 22 FDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGF 79 FD+ +IQ++ + F + G + +ED + + E + + G Sbjct: 1 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEGMM-----SEAPGP 55 Query: 80 IHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTL 138 I+F F+T+ GT E+ + AF +D G+I D + ++ ++ Sbjct: 56 INFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMG--------- 106 Query: 139 NEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 + + V ++++ ++ G EF K Sbjct: 107 ---DRFTDEEVDEMYREAPIDKKGNFNYVEFTRILK 139 >3A4U-B nrPDB Length = 143 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Query: 96 TLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKL 155 E +L + F+++D + + + E+ T + V+K GS E + + + Sbjct: 66 PQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRD 124 Query: 156 MDKNEDGYITLDEFREGSK 174 DKN DGYI EF + + Sbjct: 125 DDKNNDGYIDYAEFAKSLQ 143 Score = 26.9 bits (58), Expect = 5.1, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 25/84 (29%), Gaps = 11/84 (13%) Query: 17 KQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPE-----------DFA 65 K +E+Q + + L + E + Sbjct: 59 KPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINII 118 Query: 66 NHLFTVFDKDNNGFIHFEEFITVL 89 + + DK+N+G+I + EF L Sbjct: 119 DGVLRDDDKNNDGYIDYAEFAKSL 142 >2K7B-A nrPDB Length = 76 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 30/67 (44%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 + F FDKD +G+I+ + + T E +L + ++N G++ FD+ + Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFV 69 Query: 123 TIVASVY 129 ++ Sbjct: 70 ELMGPKL 76 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 34/75 (45%), Gaps = 12/75 (16%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 E+L AF +D + DGYI ++ + ++ M EM + ++ + ++ Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMP------------TEMELIELSQQINM 57 Query: 159 NEDGYITLDEFREGS 173 N G++ D+F E Sbjct: 58 NLGGHVDFDDFVELM 72 >5ZH6-A nrPDB Length = 107 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 + +F + D+D +GFI +E F+ S T+R E + + D +HDG Sbjct: 36 NKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDSDHDGK 95 Query: 116 ITFDEMLTIVAS 127 I DE +V + Sbjct: 96 IGVDEFKAMVKA 107 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 30/81 (37%), Gaps = 9/81 (11%) Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 + L+ F++ D + G+I DE+ ++ S DE Sbjct: 36 NKSDANLAKVFDILDQDRSGFIEVDEL-----KLFLQNFSATARELDET----ETNAFLA 86 Query: 155 LMDKNEDGYITLDEFREGSKV 175 D + DG I +DEF+ K Sbjct: 87 AGDSDHDGKIGVDEFKAMVKA 107 >3AKA-A nrPDB Length = 166 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 37/115 (32%), Gaps = 20/115 (17%) Query: 69 FTVFDKDNNGFIHFEEF------------ITVLSTTSRGT---LEEKLSWAFELYDLNHD 113 FT FD+D NG I +F + S + E + D + D Sbjct: 10 FTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGIADRDGD 69 Query: 114 GYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE 168 IT +E +T + + + + D + DG +T+ + Sbjct: 70 QRITREEFVTGAVKRLR-----DKPDRFAEIARPFLHAALGVADTDGDGAVTVAD 119 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 51/168 (30%), Gaps = 36/168 (21%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPF--------------GSPEDFANHLF 69 R I F +D +G + R DF K G E L Sbjct: 3 ERRIAARFTTFDQD-GNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLA 61 Query: 70 TVFDKDNNGFIHFEEFITVLSTTSRGTLEE-------KLSWAFELYDLNHDGYITFDEML 122 + D+D + I EEF+T R + L A + D + DG +T + Sbjct: 62 GIADRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTA 121 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + + PE ++ +D + DG + E Sbjct: 122 RALTA--------------FGVPEDLARQAAAALDTDGDGKVGETEIV 155 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 34/81 (41%), Gaps = 3/81 (3%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEAT---PEMRVKKIFK 154 E +++ F +D + +G+I + ++ G + +A E + + Sbjct: 3 ERRIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAG 62 Query: 155 LMDKNEDGYITLDEFREGSKV 175 + D++ D IT +EF G+ Sbjct: 63 IADRDGDQRITREEFVTGAVK 83 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 32/94 (34%), Gaps = 8/94 (8%) Query: 42 QLAREDFVKIYKQFFPFGS------PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRG 95 ++ RE+FV + F + V D D +G + + L+ Sbjct: 71 RITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTARALTAFG-- 128 Query: 96 TLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 E+ A D + DG + E++ A + Sbjct: 129 VPEDLARQAAAALDTDGDGKVGETEIVPAFARYF 162 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 17/50 (34%), Gaps = 3/50 (6%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL 89 G + D + F G PED A D D +G + E + Sbjct: 112 DGAVTVADTARALTAF---GVPEDLARQAAAALDTDGDGKVGETEIVPAF 158 >4P5X-A nrPDB Length = 315 Score = 47.0 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 55/155 (35%), Gaps = 26/155 (16%) Query: 43 LAREDFVKIYKQFFPFGSPEDFANHLFT-VFDKDNNGFIHFEEFITVLSTTSRGTLEEKL 101 + EDFV+ Y + + L V D+ +G I ++EF+ S + Sbjct: 38 MTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCA--PDSMF 95 Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVY-----------------------KMMGSMVTL 138 AF+L+D + +G +TF+ + I K + Sbjct: 96 IVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFT 155 Query: 139 NEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 + ++ F L DK++ G I+ +F + Sbjct: 156 QFLQELQLEHARQAFALKDKSKSGMISGLDFSDIM 190 Score = 32.3 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 37/96 (38%), Gaps = 17/96 (17%) Query: 100 KLSWAFELY---DLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 +L F Y +++ + Y+T ++ + + L D + V+ + + Sbjct: 19 ELRNIFLQYASTEVDGERYMTPEDFVQ----------RYLGLYNDPNSNPKIVQLLAGVA 68 Query: 157 DKNEDGYITLDEFREG----SKVDPSIIGALNLYDG 188 D+ +DG I+ EF D I A L+D Sbjct: 69 DQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDK 104 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 44/141 (31%), Gaps = 38/141 (26%) Query: 27 IQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFE--- 83 I Q G G ++ ++F+ +P+ F +FDK NG + FE Sbjct: 60 IVQLLAGVADQTKDGLISYQEFLAFESVLC---APDSMFIVAFQLFDKSGNGEVTFENVK 116 Query: 84 ------------------EFI--------------TVLSTTSRGTLEEKLSWAFELYDLN 111 EFI T + + E AF L D + Sbjct: 117 EIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKS 176 Query: 112 HDGYITFDEMLTIVASVYKMM 132 G I+ + I+ ++ M Sbjct: 177 KSGMISGLDFSDIMVTIRSHM 197 >3PAT-A nrPDB Length = 110 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 3/64 (4%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTT---SRGTLEEKLSWAFELYDLNHDGYITFDEM 121 +F D D +GFI EE VL + R + + + D + DG I DE Sbjct: 44 VKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGIDEF 103 Query: 122 LTIV 125 T+V Sbjct: 104 ETLV 107 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 9/70 (12%) Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 + F+ D + G+I +E+ V + G +T E K K DK+ Sbjct: 43 DVKKVFKAIDADASGFIEEEEL-KFVLKSFAADGRDLTDAE--------TKAFLKAADKD 93 Query: 160 EDGYITLDEF 169 DG I +DEF Sbjct: 94 GDGKIGIDEF 103 Score = 30.0 bits (66), Expect = 0.60, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 3/70 (4%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS--PEDFANHLFTVFDKDNNGFI 80 ++++ K D SG + E+ + K F G + DKD +G I Sbjct: 40 SANDVKKVFKAIDADA-SGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKI 98 Query: 81 HFEEFITVLS 90 +EF T++ Sbjct: 99 GIDEFETLVH 108 >2K2I-A nrPDB Length = 79 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 27/73 (36%) Query: 56 FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 ++ F +FD D G I F+ V +E+L + D + DG Sbjct: 4 MSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGE 63 Query: 116 ITFDEMLTIVASV 128 ++ E L I+ Sbjct: 64 VSEQEFLRIMKKT 76 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 35/84 (41%), Gaps = 12/84 (14%) Query: 92 TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKK 151 S +E++ AF+L+D + G I+F + + + E + +++ Sbjct: 4 MSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELG------------ENLTDEELQE 51 Query: 152 IFKLMDKNEDGYITLDEFREGSKV 175 + D++ DG ++ EF K Sbjct: 52 MIDEADRDGDGEVSEQEFLRIMKK 75 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Query: 16 LKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKD 75 K S + EI + K F D +G+++ ++ ++ K+ + E+ + D+D Sbjct: 2 QKMSEKDTKEEILKAFKLFDDD-ETGKISFKNLKRVAKELGENLTDEELQEMI-DEADRD 59 Query: 76 NNGFIHFEEFITVLSTTS 93 +G + +EF+ ++ TS Sbjct: 60 GDGEVSEQEFLRIMKKTS 77 >1RTP-1 nrPDB Length = 109 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 7/82 (8%) Query: 53 KQFFPF----GSPEDFANHLFTVFDKDNNGFIHFEEFITVL---STTSRGTLEEKLSWAF 105 K+FF D +F + DKD +GFI +E ++L S+ +R ++ Sbjct: 27 KKFFQMVGLKKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLM 86 Query: 106 ELYDLNHDGYITFDEMLTIVAS 127 D + DG I +E T+VA Sbjct: 87 AAGDKDGDGKIGVEEFSTLVAE 108 Score = 39.6 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 30/76 (39%), Gaps = 9/76 (11%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 + + + F + D + G+I DE+ +I+ ++ K + Sbjct: 36 KKKSADDVKKVFHILDKDKSGFIEEDELGSILKGF---------SSDARDLSAKETKTLM 86 Query: 154 KLMDKNEDGYITLDEF 169 DK+ DG I ++EF Sbjct: 87 AAGDKDGDGKIGVEEF 102 >1NYA-A nrPDB Length = 176 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 9/93 (9%) Query: 40 SGQLAREDFVKIYKQF-FPFGSPE------DFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 G L E F+++ + F G + + DK+ +G I+ +EF L+ Sbjct: 72 DGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEFAAWLTAL 131 Query: 93 SRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 E + AF D N +G ++ DE+LT V Sbjct: 132 GMSKAEA--AEAFNQVDTNGNGELSLDELLTAV 162 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 27/159 (16%), Positives = 51/159 (32%), Gaps = 33/159 (20%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFE 83 +E Q + F +D +G + + F + + E ++G + E Sbjct: 30 EKEAQHIAEAFGKD--AGAAEVQTLKNAFGGLFDYLAKEAGVG---------SDGSLTEE 78 Query: 84 EFITVLSTTSRGTLEEK--------LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSM 135 +FI V E + + D N DG I DE + ++ Sbjct: 79 QFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEFAAWLTALG------ 132 Query: 136 VTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 + + F +D N +G ++LDE + Sbjct: 133 --------MSKAEAAEAFNQVDTNGNGELSLDELLTAVR 163 Score = 39.6 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 26/69 (37%), Gaps = 3/69 (4%) Query: 33 GFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 G GQ+ ++F G + A F D + NG + +E +T + Sbjct: 109 GMCDKNADGQINADEFAAWLTAL---GMSKAEAAEAFNQVDTNGNGELSLDELLTAVRDF 165 Query: 93 SRGTLEEKL 101 G L+ +L Sbjct: 166 HFGRLDVEL 174 Score = 33.9 bits (76), Expect = 0.050, Method: Composition-based stats. Identities = 28/124 (22%), Positives = 44/124 (35%), Gaps = 19/124 (15%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLE-------EKLSWAF-ELYD--- 109 D F +D D NG + +F + + + L AF L+D Sbjct: 5 ASDRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLA 64 Query: 110 ----LNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYIT 165 + DG +T ++ + + ++ G VK I + DKN DG I Sbjct: 65 KEAGVGSDGSLTEEQFIRVTENLIFEQGEASFN----RVLGPVVKGIVGMCDKNADGQIN 120 Query: 166 LDEF 169 DEF Sbjct: 121 ADEF 124 Score = 28.1 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 26/76 (34%), Gaps = 3/76 (3%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMR---VKKIFKL 155 ++L F+ +D + +G + + + + G E + + K Sbjct: 7 DRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAKE 66 Query: 156 MDKNEDGYITLDEFRE 171 DG +T ++F Sbjct: 67 AGVGSDGSLTEEQFIR 82 >2SAS-A nrPDB Length = 185 Score = 46.2 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 53/126 (42%), Gaps = 19/126 (15%) Query: 65 ANHLFTVF-DKDNNGFIHFEEFITVLST---------------TSRGTLEEKLSWAFELY 108 F F D +++G I +F +++ + + +LE++ Sbjct: 10 IKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRDLKGRA 69 Query: 109 DLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE 168 D+N D ++++E L + S+ L A + R+ +FK MD + DG + L+E Sbjct: 70 DINKDDVVSWEEYLAMWEKTIATCKSVADLP---AWCQNRIPFLFKGMDVSGDGIVDLEE 126 Query: 169 FREGSK 174 F+ K Sbjct: 127 FQNYCK 132 >4MSP-A nrPDB Length = 200 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 45/96 (46%), Gaps = 4/96 (4%) Query: 74 KDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMG 133 K+ G I E + + +F+ DLN D ++ DE+ + ++ G Sbjct: 102 KEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHG 161 Query: 134 SMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 ++V +E+ + V+ IF D+++DG+I+ EF Sbjct: 162 AVV----NESHHDALVEDIFDKEDEDKDGFISAREF 193 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 8/23 (34%), Positives = 11/23 (47%) Query: 63 DFANHLFTVFDKDNNGFIHFEEF 85 +F D+D +GFI EF Sbjct: 171 ALVEDIFDKEDEDKDGFISAREF 193 >2KYF-A nrPDB Length = 108 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 26/82 (31%), Gaps = 9/82 (10%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 +L F + D + G+I DE+ + + K Sbjct: 36 SKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTAS---------ETKTFL 86 Query: 154 KLMDKNEDGYITLDEFREGSKV 175 D + DG I +EF+E + Sbjct: 87 AAADHDGDGKIGAEEFQEMVQS 108 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 31/82 (37%), Gaps = 7/82 (8%) Query: 53 KQFFPFG----SPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWAF 105 K+FF +F + D D +GFI +E F+ + +R + Sbjct: 27 KKFFQISGMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFL 86 Query: 106 ELYDLNHDGYITFDEMLTIVAS 127 D + DG I +E +V S Sbjct: 87 AAADHDGDGKIGAEEFQEMVQS 108 Score = 29.6 bits (65), Expect = 0.74, Method: Composition-based stats. Identities = 12/85 (14%), Positives = 28/85 (32%), Gaps = 3/85 (3%) Query: 9 SKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS--PEDFAN 66 S + + ++++ + D SG + ++ ++F Sbjct: 25 SPKKFFQISGMSKKSSSQLKEIFRILDND-QSGFIEEDELKYFLQRFESGARVLTASETK 83 Query: 67 HLFTVFDKDNNGFIHFEEFITVLST 91 D D +G I EEF ++ + Sbjct: 84 TFLAAADHDGDGKIGAEEFQEMVQS 108 >1TTX-A nrPDB Length = 109 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 27/66 (40%), Gaps = 3/66 (4%) Query: 63 DFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 + +F D D +G++ EE F+ + +R E + D + DG I + Sbjct: 42 NQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAE 101 Query: 120 EMLTIV 125 E +V Sbjct: 102 EFQEMV 107 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 25/73 (34%), Gaps = 9/73 (12%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE 160 + F D + GY+ +E+ + + E K + D + Sbjct: 44 VKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELT---------ESETKSLMAAADNDG 94 Query: 161 DGYITLDEFREGS 173 DG I +EF+E Sbjct: 95 DGKIGAEEFQEMV 107 Score = 33.5 bits (75), Expect = 0.059, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 29/87 (33%), Gaps = 3/87 (3%) Query: 7 KLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP--EDF 64 + +++ + F+ + SG L E+ ++F E Sbjct: 24 TFEPQKFFQTSGLSKMSANQVKDVFR-FIDNDQSGYLDEEELKFFLQKFESGARELTESE 82 Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLST 91 L D D +G I EEF ++ + Sbjct: 83 TKSLMAAADNDGDGKIGAEEFQEMVHS 109 >1G33-A nrPDB Length = 73 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 3/71 (4%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVL---STTSRGTLEEKLSWAFELYDLNHDGYI 116 D +F + DKD +GFI +E ++L S+ +R ++ D + DG I Sbjct: 2 KSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKI 61 Query: 117 TFDEMLTIVAS 127 +E T+VA Sbjct: 62 GVEEFSTLVAE 72 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 29/74 (39%), Gaps = 9/74 (12%) Query: 96 TLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKL 155 + + F + D + G+I DE+ +I+ ++ K + Sbjct: 2 KSADDVKKVFHILDKDKSGFIEEDELGSILKGF---------SSDARDLSAKETKTLMAA 52 Query: 156 MDKNEDGYITLDEF 169 DK+ DG I ++EF Sbjct: 53 GDKDGDGKIGVEEF 66 >3I5H-B nrPDB Length = 153 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 43/108 (39%), Gaps = 15/108 (13%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 FT+ D+D +GFI E+ + S+ R +++L+ + G + F LT Sbjct: 17 ELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAMLKEC----PGQLNFTAFLT 72 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 + PE ++ F + D++ G+I D ++ Sbjct: 73 LFGEK-----------VSGTDPEDALRNAFSMFDEDGQGFIPEDYLKD 109 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 L++CP GQL F+ ++ + PED + F++FD+D GFI + +L Sbjct: 58 LKECP-GQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMGD 116 Query: 95 GTLEEKLSWAFELYDLNH 112 +E++ ++ L + Sbjct: 117 NFSKEEIKNVWKDAPLKN 134 >2NLN-A nrPDB Length = 108 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 27/66 (40%), Gaps = 3/66 (4%) Query: 63 DFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFD 119 +F D D +G++ +E F+ + +R E + + D + DG I D Sbjct: 41 SQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGAD 100 Query: 120 EMLTIV 125 E +V Sbjct: 101 EFQEMV 106 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 26/73 (35%), Gaps = 9/73 (12%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE 160 + F D + GY+ DE+ + ++ E K + D + Sbjct: 43 VKDIFRFIDNDQSGYLDGDELKYFLQKF---------QSDARELTESETKSLMDAADNDG 93 Query: 161 DGYITLDEFREGS 173 DG I DEF+E Sbjct: 94 DGKIGADEFQEMV 106 Score = 33.5 bits (75), Expect = 0.055, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 29/87 (33%), Gaps = 3/87 (3%) Query: 7 KLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP--EDF 64 + +++ + F+ + SG L ++ ++F E Sbjct: 23 TFEPQKFFQTSGLSKMSASQVKDIFR-FIDNDQSGYLDGDELKYFLQKFQSDARELTESE 81 Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLST 91 L D D +G I +EF ++ + Sbjct: 82 TKSLMDAADNDGDGKIGADEFQEMVHS 108 >2K2A-A nrPDB Length = 70 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 28/64 (43%) Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 + F ++DK+ NG+I + +L+ E L + D + G + F+E Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEF 61 Query: 122 LTIV 125 + ++ Sbjct: 62 MGVM 65 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 12/74 (16%) Query: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 ++++L AF LYD +GYI+ D M I+A DE + + + Sbjct: 1 MQQELREAFRLYDKEGNGYISTDVMREILA------------ELDETLSSEDLDAMIDEI 48 Query: 157 DKNEDGYITLDEFR 170 D + G + +EF Sbjct: 49 DADGSGTVDFEEFM 62 Score = 34.6 bits (78), Expect = 0.028, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 35/66 (53%), Gaps = 2/66 (3%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFE 83 ++E+++ + + ++ +G ++ + +I + S ED + + D D +G + FE Sbjct: 2 QQELREAFRLYDKE-GNGYISTDVMREILAELDETLSSEDL-DAMIDEIDADGSGTVDFE 59 Query: 84 EFITVL 89 EF+ V+ Sbjct: 60 EFMGVM 65 >1BU3-A nrPDB Length = 109 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 7/83 (8%) Query: 52 YKQFFP----FGSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWA 104 YK FF D F V D+D +GFI +E F+ V S +R + + Sbjct: 27 YKAFFAKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAF 86 Query: 105 FELYDLNHDGYITFDEMLTIVAS 127 + D + DG I DE +V + Sbjct: 87 LKAGDSDGDGAIGVDEWAALVKA 109 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 31/81 (38%), Gaps = 9/81 (11%) Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 + + AF + D + G+I DE+ + V+ +T E K K Sbjct: 38 AKSADDIKKAFFVIDQDKSGFIEEDEL-KLFLQVFSAGARALTDAE--------TKAFLK 88 Query: 155 LMDKNEDGYITLDEFREGSKV 175 D + DG I +DE+ K Sbjct: 89 AGDSDGDGAIGVDEWAALVKA 109 >4D1E-A nrPDB Length = 876 Score = 44.7 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 32/176 (18%), Positives = 54/176 (30%), Gaps = 20/176 (11%) Query: 7 KLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFAN 66 +L ++ L + T + I+ + L + G ++ N Sbjct: 682 QLIQEALVFDNKHTNYTMEHIRVGWELLLTTI---ARTINEVETQILTRDAKGITQEQMN 738 Query: 67 HL---FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 F FD+ NG + E+F L + E + + L D N G +TF + Sbjct: 739 EFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTVTFQSFID 798 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKI-FKLMDKNEDGYITLDEFREGSKVDPS 178 + D T E + DK YI +E R D + Sbjct: 799 FMTR----------ETADTDTAEQVIASFRILASDKP---YILAEELRRELPPDQA 841 >1A75-A nrPDB Length = 108 Score = 44.7 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 7/83 (8%) Query: 52 YKQFFP----FGSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWA 104 YK FF G D F D+D +GFI +E F+ V +R + + Sbjct: 26 YKAFFAKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAF 85 Query: 105 FELYDLNHDGYITFDEMLTIVAS 127 + D + DG I +E + +V + Sbjct: 86 LKAGDSDGDGAIGVEEWVALVKA 108 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 32/82 (39%), Gaps = 9/82 (10%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 G + + AF D + G+I DE+ + V+K +T E K Sbjct: 36 SGKSADDIKKAFVFIDQDKSGFIEEDEL-KLFLQVFKAGARALTDAE--------TKAFL 86 Query: 154 KLMDKNEDGYITLDEFREGSKV 175 K D + DG I ++E+ K Sbjct: 87 KAGDSDGDGAIGVEEWVALVKA 108 >6FSA-D nrPDB Length = 199 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 40/104 (38%), Gaps = 3/104 (2%) Query: 27 IQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHL--FTVFDKDNNGFIHFEE 84 ++ K + S + + F+ + + + + + VFDK+ NG + E Sbjct: 97 LRVLGKPKQEELNSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAE 156 Query: 85 FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 VL+T E+++ + +G I ++ + + + Sbjct: 157 LRHVLATLGEKLTEDEVEKLMA-GQEDSNGCINYEAFVKHIMAG 199 Score = 33.9 bits (76), Expect = 0.040, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 41/112 (36%), Gaps = 13/112 (11%) Query: 63 DFANHLFTVFDK--DNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 + FT+FD+ I + + VL + + ++ G +E Sbjct: 56 EEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVL--------GKPKQEE 107 Query: 121 M--LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + + + M ++ N+D T E V + ++ DK +G + E R Sbjct: 108 LNSKMMDFDTFLPMLQHISKNKDTGTYEDFV-EGLRVFDKEGNGTVMGAELR 158 Score = 27.3 bits (59), Expect = 3.9, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 38/98 (38%), Gaps = 16/98 (16%) Query: 76 NNGFIHFEEFITVLSTTSRGT---LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 N+ + F+ F+ +L S+ E ++D +G + E+ ++A++ Sbjct: 109 NSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG--- 165 Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 E E V+K+ ++ +G I + F Sbjct: 166 ---------EKLTEDEVEKLMA-GQEDSNGCINYEAFV 193 >3JAX-C nrPDB Length = 151 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 43/112 (38%), Gaps = 11/112 (9%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFE--LYDLNHDGYITF 118 F +FD+ +G I + + V+ + ++ D + + F Sbjct: 8 QTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLKTLKF 67 Query: 119 DEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 ++ L ++ ++ K N+D+ E V + ++ DK +G + E R Sbjct: 68 EQFLPMMQTIAK--------NKDQGCFEDYV-EGLRVFDKEGNGTVMGAEIR 110 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 42 QLAREDFVKIYKQFFPFGSPEDFANHL--FTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 L E F+ + + F +++ VFDK+ NG + E VL T EE Sbjct: 64 TLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEE 123 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIV 125 ++ ++ + +G I ++E++ +V Sbjct: 124 EVEQLVAGHE-DSNGCINYEELVRMV 148 Score = 32.3 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 22/162 (13%), Positives = 54/162 (33%), Gaps = 18/162 (11%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHL-FTVFDKDN 76 + E ++ + F R G++ + + + + L D+ N Sbjct: 3 DFSEEQTAEFKEAFQLFDR-TGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMN 61 Query: 77 NGFIHFEEFITVLSTTSRGTLE---EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMG 133 + FE+F+ ++ T ++ + E ++D +G + E+ Sbjct: 62 LKTLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEI------------ 109 Query: 134 SMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 V + E E V+++ ++ +G I +E Sbjct: 110 RHVLVTLGEKMTEEEVEQLVA-GHEDSNGCINYEELVRMVLS 150 >1RK9-A nrPDB Length = 110 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 3/82 (3%) Query: 49 VKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL---STTSRGTLEEKLSWAF 105 K ++ D +F + DKD +GFI +E +L S +R ++ Sbjct: 28 KKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLM 87 Query: 106 ELYDLNHDGYITFDEMLTIVAS 127 D + DG I DE T+VA Sbjct: 88 AAGDKDGDGKIGVDEFSTLVAE 109 Score = 39.6 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 28/76 (36%), Gaps = 9/76 (11%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIF 153 + + + F + D + G+I DE+ I+ + K + Sbjct: 37 KKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGF---------SPDARDLSAKETKMLM 87 Query: 154 KLMDKNEDGYITLDEF 169 DK+ DG I +DEF Sbjct: 88 AAGDKDGDGKIGVDEF 103 >2M8U-A nrPDB Length = 77 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 28/64 (43%) Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 + F VFD+D NG++ + VL+ +++ D + GY+ ++ Sbjct: 10 KAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSGYVQYETF 69 Query: 122 LTIV 125 + ++ Sbjct: 70 VGML 73 Score = 39.6 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 35/81 (43%), Gaps = 12/81 (14%) Query: 90 STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRV 149 S + + ++ AF+++D + +GY+T D + ++ + MM P + Sbjct: 2 SHMNHINTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMM------------PADEI 49 Query: 150 KKIFKLMDKNEDGYITLDEFR 170 +++ D GY+ + F Sbjct: 50 EEMIYEADPQNSGYVQYETFV 70 Score = 26.5 bits (57), Expect = 6.2, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 18/36 (50%), Gaps = 7/36 (19%) Query: 149 VKKIFKLMDKNEDGYIT-------LDEFREGSKVDP 177 V + FK+ D++ +GY+T L+E + D Sbjct: 13 VIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADE 48 >1JUO-A nrPDB Length = 198 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 40/109 (36%), Gaps = 9/109 (8%) Query: 26 EIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEF 85 E + L SG + +F +++ + F FD D +G + +E Sbjct: 73 ETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW-------RQHFISFDTDRSGTVDPQEL 125 Query: 86 ITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 L+T + ++ + Y +G ITFD+ + + + S Sbjct: 126 QKALTTMGFRLSPQAVNSIAKRYST--NGKITFDDYIACCVKLRALTDS 172 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 13/102 (12%), Positives = 30/102 (29%), Gaps = 23/102 (22%) Query: 76 NNGFIHFEEFITVLSTTS----RGTLEEKLSWAF-ELYDLNHDGYITFDEMLTIVASVYK 130 +G I +E L+ + + + D + G + F+E + A + Sbjct: 45 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNG 104 Query: 131 MMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 ++ F D + G + E ++ Sbjct: 105 ------------------WRQHFISFDTDRSGTVDPQELQKA 128 >5TBY-C nrPDB Length = 195 Score = 43.5 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 38/99 (38%), Gaps = 3/99 (3%) Query: 27 IQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHL--FTVFDKDNNGFIHFEE 84 ++ K + + + E F+ + + + + + VFDK+ NG + E Sbjct: 93 LRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAE 152 Query: 85 FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 VL+T E+++ + +G I ++ + Sbjct: 153 LRHVLATLGERLTEDEVEKLMA-GQEDSNGCINYEAFVK 190 Score = 33.5 bits (75), Expect = 0.061, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 41/112 (36%), Gaps = 13/112 (11%) Query: 63 DFANHLFTVFDK--DNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 + F +FD+ I + + VL + + ++ G +E Sbjct: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVL--------GKPRQEE 103 Query: 121 MLTIVA--SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + T + + M ++ N+D T E V + ++ DK +G + E R Sbjct: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFV-EGLRVFDKEGNGTVMGAELR 154 Score = 26.9 bits (58), Expect = 4.7, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 35/93 (37%), Gaps = 16/93 (17%) Query: 81 HFEEFITVLSTTSRGT---LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 FE F+ +L S+ E ++D +G + E+ ++A++ Sbjct: 110 DFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG-------- 161 Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 E E V+K+ ++ +G I + F Sbjct: 162 ----ERLTEDEVEKLMA-GQEDSNGCINYEAFV 189 >2NCO-A nrPDB Length = 102 Score = 43.1 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 8/83 (9%) Query: 96 TLEEKL---SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKI 152 +E KL F+ YD + G + DE+ ++ Y MG E VK Sbjct: 9 EVEAKLDVARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKED-----VKIW 63 Query: 153 FKLMDKNEDGYITLDEFREGSKV 175 ++ D N DG ++L+E+ + Sbjct: 64 LQMADTNSDGSVSLEEYEDLIIK 86 Score = 34.3 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 7/81 (8%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTT-------SRGTLEEKLSWAFELYDLNHDGY 115 D A LF +DKD +G + +E +L T + +E + ++ D N DG Sbjct: 15 DVARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGS 74 Query: 116 ITFDEMLTIVASVYKMMGSMV 136 ++ +E ++ + G V Sbjct: 75 VSLEEYEDLIIKSLQKAGIRV 95 >5MRA-A nrPDB Length = 167 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 40/109 (36%), Gaps = 9/109 (8%) Query: 26 EIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEF 85 E + L SG + +F +++ + F FD D +G + +E Sbjct: 42 ETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW-------RQHFISFDTDRSGTVDPQEL 94 Query: 86 ITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 L+T + ++ + Y +G ITFD+ + + + S Sbjct: 95 QKALTTMGFRLSPQAVNSIAKRYST--NGKITFDDYIACCVKLRALTDS 141 Score = 31.6 bits (70), Expect = 0.24, Method: Composition-based stats. Identities = 13/102 (12%), Positives = 30/102 (29%), Gaps = 23/102 (22%) Query: 76 NNGFIHFEEFITVLSTTS----RGTLEEKLSWAF-ELYDLNHDGYITFDEMLTIVASVYK 130 +G I +E L+ + + + D + G + F+E + A + Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNG 73 Query: 131 MMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 ++ F D + G + E ++ Sbjct: 74 ------------------WRQHFISFDTDRSGTVDPQELQKA 97 >4PAL-A nrPDB Length = 108 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 33/82 (40%), Gaps = 3/82 (3%) Query: 49 VKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWAF 105 + + + D F V D+D +GFI +E F+ S ++R + + Sbjct: 27 KEFFAKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFL 86 Query: 106 ELYDLNHDGYITFDEMLTIVAS 127 D + DG I DE ++ + Sbjct: 87 ADGDKDGDGMIGVDEFAAMIKA 108 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 29/77 (37%), Gaps = 9/77 (11%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + + AF + D + G+I DE+ + + A + K DK Sbjct: 41 DDVKKAFYVIDQDKSGFIEEDELKLFLQNF---------SPSARALTDAETKAFLADGDK 91 Query: 159 NEDGYITLDEFREGSKV 175 + DG I +DEF K Sbjct: 92 DGDGMIGVDEFAAMIKA 108 >2MBX-A nrPDB Length = 109 Score = 42.7 bits (99), Expect = 8e-05, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 29/72 (40%), Gaps = 3/72 (4%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 +F + D+D + F+ +E F+ S +R + + + D + DG Sbjct: 38 AKSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAETKVFLKAGDSDGDGK 97 Query: 116 ITFDEMLTIVAS 127 I DE ++ + Sbjct: 98 IGVDEFGAMIKA 109 Score = 33.9 bits (76), Expect = 0.039, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 36/98 (36%), Gaps = 11/98 (11%) Query: 78 GFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 G + F T + ++ + + FE+ D + ++ DE+ + + ++ Sbjct: 23 GSFDHKAFFTKVGLAAKSPAD--IKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARAL-- 78 Query: 138 LNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 + K K D + DG I +DEF K Sbjct: 79 -------SDAETKVFLKAGDSDGDGKIGVDEFGAMIKA 109 >2W4G-C nrPDB Length = 145 Score = 42.7 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 41/107 (38%), Gaps = 11/107 (10%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLN--HDGYITFDEMLT 123 F +FD+ + I + ++ + +++ + ITF+E L Sbjct: 7 KEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKITFEEFLP 66 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 ++ + N+D+ T E V + ++ DK +G + E R Sbjct: 67 MLQAA--------ANNKDQGTFEDFV-EGLRVFDKEGNGTVMGAELR 104 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 41/96 (42%), Gaps = 3/96 (3%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHL--FTVFDKDNNGFIHFEEFITVLSTT 92 + + ++ E+F+ + + F + + VFDK+ NG + E VL+T Sbjct: 51 KEEMNAKKITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATL 110 Query: 93 SRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 EE++ + + +G I ++ + + SV Sbjct: 111 GEKMTEEEVEELMK-GQEDSNGCINYEAFVKHIMSV 145 Score = 30.4 bits (67), Expect = 0.51, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 43/115 (37%), Gaps = 8/115 (6%) Query: 25 REIQQWHKGFLRDCPSG--QLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKD--NNGFI 80 EI + + FL +G ++ I + + N + K+ N I Sbjct: 1 DEINDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPT-NAEINKILGNPSKEEMNAKKI 59 Query: 81 HFEEFITVLSTTSRGT---LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 FEEF+ +L + E ++D +G + E+ ++A++ + M Sbjct: 60 TFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKM 114 >3CS1-A nrPDB Length = 219 Score = 42.7 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 34/184 (18%), Positives = 67/184 (36%), Gaps = 32/184 (17%) Query: 3 AKTSKLSKDDLTCLKQ-----STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFP 57 K +K K+ ++Q T ++ + K F ++ +G+L ++ +Y Sbjct: 21 GKKAKDRKEAWERIRQAIPREKTAEAKQRRIELFKKFDKN-ETGKLCYDE---VYSGCLE 76 Query: 58 FGSPEDFANHLFTV----FDK--------DNNGFIHFEEFITVLSTTSRGTLEEKLSWAF 105 ++F + + + FDK +N G F EF+ +L+ F Sbjct: 77 VLKLDEFTSRVRDITKRAFDKSRTLGSKLENKGSEDFVEFLEFRLMLCYIYDFFELTVMF 136 Query: 106 ELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYIT 165 + D + + + +E V + + +FK +DKN G +T Sbjct: 137 DEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAA-----------LFKELDKNGTGSVT 185 Query: 166 LDEF 169 DEF Sbjct: 186 FDEF 189 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 31/84 (36%), Gaps = 2/84 (2%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSR-GTLEEKLSWAFELYDLNHDGYITFDEML 122 +F D N + EEF + G E + F+ D N G +TFDE Sbjct: 131 ELTVMFDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAALFKELDKNGTGSVTFDEFA 190 Query: 123 TIVASVYKMMGSMVTLNEDEATPE 146 ++V K+ N E+ E Sbjct: 191 AWASAV-KLDADGDPDNVPESALE 213 Score = 34.6 bits (78), Expect = 0.029, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 25/64 (39%), Gaps = 2/64 (3%) Query: 34 FLRDCPSG--QLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLST 91 F SG + E+F + + +G+ + LF DK+ G + F+EF S Sbjct: 136 FDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAALFKELDKNGTGSVTFDEFAAWASA 195 Query: 92 TSRG 95 Sbjct: 196 VKLD 199 Score = 27.7 bits (60), Expect = 3.6, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 17/35 (48%) Query: 140 EDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 E A + R ++FK DKNE G + DE G Sbjct: 41 EKTAEAKQRRIELFKKFDKNETGKLCYDEVYSGCL 75 >5CPV-A nrPDB Length = 109 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 29/72 (40%), Gaps = 3/72 (4%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEE---FITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 D F + D+D +GFI +E F+ +R + + + D + DG Sbjct: 38 SKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFLKAGDSDGDGK 97 Query: 116 ITFDEMLTIVAS 127 I DE +V + Sbjct: 98 IGVDEFTALVKA 109 Score = 39.6 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 31/80 (38%), Gaps = 9/80 (11%) Query: 96 TLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKL 155 + + AF + D + G+I DE+ + +K +T E K K Sbjct: 39 KSADDVKKAFAIIDQDKSGFIEEDEL-KLFLQNFKADARALTDGE--------TKTFLKA 89 Query: 156 MDKNEDGYITLDEFREGSKV 175 D + DG I +DEF K Sbjct: 90 GDSDGDGKIGVDEFTALVKA 109 >2PMY-A nrPDB Length = 91 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 28/68 (41%), Gaps = 4/68 (5%) Query: 58 FGSPEDFAN--HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 G E+ A +F D + +G + EEF + + + + F+ D + DG Sbjct: 20 DGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAE--AVFQRLDADRDGA 77 Query: 116 ITFDEMLT 123 ITF E Sbjct: 78 ITFQEFAR 85 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 25/74 (33%), Gaps = 14/74 (18%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 +L F D N G + +E + + + +F+ +D Sbjct: 27 ARLRSVFAACDANRSGRLEREEFRALCTELR--------------VRPADAEAVFQRLDA 72 Query: 159 NEDGYITLDEFREG 172 + DG IT EF G Sbjct: 73 DRDGAITFQEFARG 86 Score = 35.8 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 28/69 (40%), Gaps = 5/69 (7%) Query: 23 DRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFI 80 D E+ + F SG+L RE+F + + + A +F D D +G I Sbjct: 22 DGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPAD---AEAVFQRLDADRDGAI 78 Query: 81 HFEEFITVL 89 F+EF Sbjct: 79 TFQEFARGF 87 >2M1U-A nrPDB Length = 93 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 1/71 (1%) Query: 58 FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYIT 117 + F FD D +GF+ EEF ++ E +++ FE D N+ G+I Sbjct: 21 MSDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRD-GLPMTEAEITEFFEAADPNNTGFID 79 Query: 118 FDEMLTIVASV 128 + ++ SV Sbjct: 80 YKAFAAMLYSV 90 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 ++ ++ + F D G ++ E+F I + P E F D +N GFI + Sbjct: 24 EKTQLIEAFYNFDGDY-DGFVSVEEFRGIIRDGLPM--TEAEITEFFEAADPNNTGFIDY 80 Query: 83 EEFITVLSTTSR 94 + F +L + Sbjct: 81 KAFAAMLYSVDE 92 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 32/84 (38%), Gaps = 15/84 (17%) Query: 88 VLSTTSRGTLEEK--LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATP 145 L +EK L AF +D ++DG+++ +E I+ M Sbjct: 13 GLVPRGSHMSDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRDGLPM-------------T 59 Query: 146 EMRVKKIFKLMDKNEDGYITLDEF 169 E + + F+ D N G+I F Sbjct: 60 EAEITEFFEAADPNNTGFIDYKAF 83 >1SJJ-A nrPDB Length = 863 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 44/123 (35%), Gaps = 15/123 (12%) Query: 59 GSPEDFANHL---FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 G ++ N F FD+ G + E+F L + E + + + D N G Sbjct: 718 GISQEQMNEFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPNRMGV 777 Query: 116 ITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKV 175 +TF + ++ + + ++ DKN YIT+DE R Sbjct: 778 VTFQAFIDFMSR---------ETADTDTADQVMASFKILAGDKN---YITVDELRRELPP 825 Query: 176 DPS 178 D + Sbjct: 826 DQA 828 >5I2L-A nrPDB Length = 120 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 22/63 (34%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 +F +D +GFI E ++ L + D + D ++F E L I Sbjct: 33 MEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLI 92 Query: 125 VAS 127 Sbjct: 93 FRK 95 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 29/72 (40%), Gaps = 12/72 (16%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 + + F+ YD DG+I E+ ++ + + +K + K +D+ Sbjct: 31 KDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHL------------GLKNMIKEVDE 78 Query: 159 NEDGYITLDEFR 170 + D ++ EF Sbjct: 79 DFDSKLSFREFL 90 Score = 29.2 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 34/94 (36%), Gaps = 3/94 (3%) Query: 9 SKDDLTCLKQSTYFDRREIQQWHKGFL--RDCPSGQLAREDFVKIYKQFFPFGSPEDFAN 66 S+ + F R++I+ K F G + + + ++ Sbjct: 12 SRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLG-APQTHLGLK 70 Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEK 100 ++ D+D + + F EF+ + + G L+E Sbjct: 71 NMIKEVDEDFDSKLSFREFLLIFRKAAAGELQED 104 >1QXP-A nrPDB Length = 900 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 40/112 (35%), Gaps = 7/112 (6%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLN---HDGYIT 117 P + L F + G ++ I + EE++ F+ D I+ Sbjct: 492 PNKEGDFLLRFFSEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDMEIS 551 Query: 118 FDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 E+ TI+ + + T + + LMD++ +G + L EF Sbjct: 552 VKELQTILNRIISKHKDLRTNG----FSLESCRSMVNLMDRDGNGKLGLVEF 599 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 34/189 (17%), Positives = 62/189 (32%), Gaps = 32/189 (16%) Query: 5 TSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCP--SGQLAREDFVKIYKQ-------F 55 T +L L EI K +++ ++ I + Sbjct: 510 TQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDMEISVKELQTILNRIISKHKDL 569 Query: 56 FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 G + + + D+D NG + EF + + F +DL+ G Sbjct: 570 RTNGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLT------IFRKFDLDKSGS 623 Query: 116 ITFDEM-LTIVASVYKMMGSMVTL-----NEDEATPE-----------MRVKKIFKLMDK 158 ++ EM + I A+ +K+ + + +DE + + KIFK +D Sbjct: 624 MSAYEMRMAIEAAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDP 683 Query: 159 NEDGYITLD 167 G I LD Sbjct: 684 ENTGTIQLD 692 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 22/141 (15%), Positives = 47/141 (33%), Gaps = 28/141 (19%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + +G+L E+F ++ + ++ F+ D +G I E Sbjct: 783 MDSDTTGKLGFEEFKYLWNNIKKW-------QGIYKRFETDRSGTIGSNELPGAFEAAGF 835 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 + S Y + G + FD ++ + + M + F+ Sbjct: 836 HLNQHIYSMIIRRY-SDETGNMDFDNFISCLVRLDAMF------------------RAFR 876 Query: 155 LMDKNEDGYI--TLDEFREGS 173 +DKN G I + E+ + + Sbjct: 877 SLDKNGTGQIQVNIQEWLQLT 897 Score = 33.5 bits (75), Expect = 0.051, Method: Composition-based stats. Identities = 24/167 (14%), Positives = 54/167 (32%), Gaps = 37/167 (22%) Query: 33 GFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDK--DNNGFIHFEEFITVLS 90 F + +G +D ++ S E+ ++ T+F K ++ I +E T+L+ Sbjct: 501 RFFSEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDMEISVKELQTILN 560 Query: 91 TTSRGTLE--------EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDE 142 + E L D + +G + E + + + Sbjct: 561 RIISKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYL---------- 610 Query: 143 ATPEMRVKKIFKLMDKNEDGYITLDE---------FREGSKVDPSII 180 IF+ D ++ G ++ E F+ ++ I+ Sbjct: 611 --------TIFRKFDLDKSGSMSAYEMRMAIEAAGFKLPCQLHQVIV 649 Score = 28.1 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 53/156 (33%), Gaps = 15/156 (9%) Query: 21 YFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHL----FTVFDKDN 76 F E+ F+R + E KI+KQ P + + + F+V K Sbjct: 651 RFADDELIIDFDNFVRCL----VRLEILFKIFKQLDPENTGTIQLDLISWLSFSVLGKLA 706 Query: 77 NGFIHFEEFITVLSTTSRGTLEEKLSW--AFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 H S EE+ + F + D ++ E++ I+ V Sbjct: 707 AAIEHHHHHHMHYSNIEANESEEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPD 765 Query: 135 MVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + T + + + +MD + G + +EF+ Sbjct: 766 LKT----DGFGIDTCRSMVAVMDSDTTGKLGFEEFK 797 >3TZ1-A nrPDB Length = 74 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 26/66 (39%) Query: 62 EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 E F V DK+ G I + +L + E+++ D + G + ++E Sbjct: 6 ERELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEF 65 Query: 122 LTIVAS 127 ++ S Sbjct: 66 KCLMMS 71 Score = 33.9 bits (76), Expect = 0.046, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Query: 22 FDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIH 81 D RE+++ + ++ G + + I K + ED ++ D D +G + Sbjct: 4 LDERELKEAFRVLDKE-KKGVIKVDVLRWILKSLGDELT-EDEIENMIAETDTDGSGTVD 61 Query: 82 FEEFITVLSTTS 93 +EEF ++ ++ Sbjct: 62 YEEFKCLMMSSD 73 Score = 31.9 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 28/73 (38%), Gaps = 12/73 (16%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 E +L AF + D G I D + I+ S+ + E ++ + D Sbjct: 6 ERELKEAFRVLDKEKKGVIKVDVLRWILKSLG------------DELTEDEIENMIAETD 53 Query: 158 KNEDGYITLDEFR 170 + G + +EF+ Sbjct: 54 TDGSGTVDYEEFK 66 >6EAZ-A nrPDB Length = 379 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 17/117 (14%), Positives = 42/117 (35%), Gaps = 9/117 (7%) Query: 78 GFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 G I + E++ +L+ ++ AF++ D++ + I E + + + K G Sbjct: 100 GVISYTEYLFLLTILTK--PHSGFHVAFKMLDVDGNEMIERKEFVKLQKIISKQDGFKTV 157 Query: 138 LNEDEATPEMRVKK-------IFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYD 187 + + VK+ + K + + EFR + + + + Sbjct: 158 KTNETEYQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFMENLQTEVQEMEFLQ 214 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 84 EFITVLS-TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 EF + T + + L F+++DL+ D ++ E L ++ + Sbjct: 293 EFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKNRM 339 Score = 31.2 bits (69), Expect = 0.29, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 20/45 (44%) Query: 47 DFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLST 91 +F + K ++ + +F +FD D + + EF+ VL Sbjct: 293 EFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKN 337 >1KFX-S nrPDB Length = 184 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 47/141 (33%), Gaps = 28/141 (19%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + +G+L E+F ++ + ++ FD D +G I E Sbjct: 67 MDSDTTGKLGFEEFKYLWNNIKRW-------QAIYKQFDTDRSGTICSSELPGAFEAAGF 119 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 E + Y + G + FD ++ + + M + FK Sbjct: 120 HLNEHLYNMIIRRY-SDESGNMDFDNFISCLVRLDAMF------------------RAFK 160 Query: 155 LMDKNEDGYI--TLDEFREGS 173 +DK+ G I + E+ + + Sbjct: 161 SLDKDGTGQIQVNIQEWLQLT 181 Score = 26.5 bits (57), Expect = 7.7, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 21/68 (30%), Gaps = 18/68 (26%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 + D + G + F+E + ++ R + I+K D + Sbjct: 61 RSMVAVMDSDTTGKLGFEEFKYLWNNI------------------KRWQAIYKQFDTDRS 102 Query: 162 GYITLDEF 169 G I E Sbjct: 103 GTICSSEL 110 >5E1J-A nrPDB Length = 741 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 31/75 (41%), Gaps = 7/75 (9%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE 160 L AF L D + +G I ++ +++ + + TL + + IF +D Sbjct: 327 LEKAFGLIDSDKNGEIDKNQ----CIKLFEQLTNYRTLPK---ISKEEFGLIFDELDDTR 379 Query: 161 DGYITLDEFREGSKV 175 D I DEF + + Sbjct: 380 DFKINKDEFADLCQA 394 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 29/88 (32%), Gaps = 7/88 (7%) Query: 65 ANHLFTVFDKDNNGFIHFE------EFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 F + D D NG I E +T T + +E+ F+ D D I Sbjct: 327 LEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPK-ISKEEFGLIFDELDDTRDFKINK 385 Query: 119 DEMLTIVASVYKMMGSMVTLNEDEATPE 146 DE + ++ + E P+ Sbjct: 386 DEFADLCQAIALRFQKEEVPSLFEHFPQ 413 Score = 34.3 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 43/104 (41%), Gaps = 6/104 (5%) Query: 10 KDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQF-----FPFGSPEDF 64 K+ L +R + + G + +G++ + +K+++Q P S E+F Sbjct: 309 KEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEF 368 Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELY 108 +F D + I+ +EF + + +E++ FE + Sbjct: 369 -GLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHF 411 >1I84-U nrPDB Length = 166 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 27/112 (24%), Positives = 40/112 (35%), Gaps = 17/112 (15%) Query: 54 QFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR-GTLEEKLSWAFELYDLNH 112 F EDF FTV D++ +G I ++ + R E+L + Sbjct: 17 SMFDETEIEDFKEA-FTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEA---- 71 Query: 113 DGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYI 164 G I F LT+ K A PE + FK++D + G I Sbjct: 72 SGPINFTVFLTMFGEKLKG-----------ADPEDVIMGAFKVLDPDGKGSI 112 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 49/111 (44%), Gaps = 10/111 (9%) Query: 19 STYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDN 76 + FD EI+ + + F + G + ++D + + + + + K+ Sbjct: 16 FSMFDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMI----KEA 71 Query: 77 NGFIHFEEFITVLSTTSRG-TLEEKLSWAFELYDLNHDGYITF---DEMLT 123 +G I+F F+T+ +G E+ + AF++ D + G I +E+LT Sbjct: 72 SGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLT 122 Score = 31.9 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 34/95 (35%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 SG + F+ ++ + PED F V D D G I +L+T E Sbjct: 72 SGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPE 131 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 ++ + + + G + + + ++ G Sbjct: 132 EIKNMWAAFPPDVAGNVDYKNICYVITHGEDAEGE 166 Score = 29.6 bits (65), Expect = 0.79, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 21/46 (45%) Query: 126 ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 A GS + + T K+ F ++D+N DG I D+ RE Sbjct: 4 AKRRAAEGSSNVFSMFDETEIEDFKEAFTVIDQNADGIIDKDDLRE 49 >1TIZ-A nrPDB Length = 67 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 31/65 (47%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 A +F FDK+ +G + +EF V S +E + FE D++ +G + DE + Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTSC 62 Query: 125 VASVY 129 + + Sbjct: 63 IEKML 67 Score = 34.6 bits (78), Expect = 0.023, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 27/68 (39%), Gaps = 12/68 (17%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 FE +D N DG ++ DE V L + + K F+ +D + + Sbjct: 4 KRVFEKFDKNKDGKLSLDEF------------REVALAFSPYFTQEDIVKFFEEIDVDGN 51 Query: 162 GYITLDEF 169 G + DEF Sbjct: 52 GELNADEF 59 Score = 32.7 bits (73), Expect = 0.10, Method: Composition-based stats. Identities = 13/26 (50%), Positives = 20/26 (76%) Query: 150 KKIFKLMDKNEDGYITLDEFREGSKV 175 K++F+ DKN+DG ++LDEFRE + Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALA 29 Score = 32.3 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Query: 28 QQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEF 85 ++ + F ++ G+L+ ++F ++ F P+ + ED F D D NG ++ +EF Sbjct: 4 KRVFEKFDKN-KDGKLSLDEFREVALAFSPYFTQEDIVK-FFEEIDVDGNGELNADEF 59 >4L9M-A nrPDB Length = 559 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 12/83 (14%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 + +F +D D +G+I EEF + ++ ++F + D + +G I+ DE+ Sbjct: 427 VDSVFKNYDHDQDGYISQEEFEKIAASFP---------FSFCVMDKDREGLISRDEITAY 477 Query: 125 VAS---VYKMMGSMVTLNEDEAT 144 +Y +G N E T Sbjct: 478 FMRASSIYSKLGLGFPHNFQETT 500 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 21/81 (25%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYI 164 F+ YD + DGYI+ +E I AS F +MDK+ +G I Sbjct: 431 FKNYDHDQDGYISQEEFEKIAASFPFS---------------------FCVMDKDREGLI 469 Query: 165 TLDEFREGSKVDPSIIGALNL 185 + DE SI L L Sbjct: 470 SRDEITAYFMRASSIYSKLGL 490 Score = 33.9 bits (76), Expect = 0.041, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 19/32 (59%) Query: 146 EMRVKKIFKLMDKNEDGYITLDEFREGSKVDP 177 + V +FK D ++DGYI+ +EF + + P Sbjct: 424 QRMVDSVFKNYDHDQDGYISQEEFEKIAASFP 455 >1IJ5-A nrPDB Length = 323 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 20/141 (14%), Positives = 56/141 (39%), Gaps = 19/141 (13%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + +G L+R++F + + + + + LF D+D + + F E++ Sbjct: 197 IDTNSNGTLSRKEFREHFVRLG--FDKKSVQDALFRYADEDESDDVGFSEYV----HLGL 250 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 L ++ +AF D + G ++ +E+ ++ + + + + F Sbjct: 251 CLLVLRILYAFA--DFDKSGQLSKEEVQKVLEDAHIP-----------ESARKKFEHQFS 297 Query: 155 LMDKNEDGYITLDEFREGSKV 175 ++D ++ ++ EF + Sbjct: 298 VVDVDDSKSLSYQEFVMLVLL 318 Score = 34.3 bits (77), Expect = 0.034, Method: Composition-based stats. Identities = 22/151 (14%), Positives = 50/151 (33%), Gaps = 22/151 (14%) Query: 22 FDRREIQQWHKGFL--RDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGF 79 + + FL SG+ + +D ++ ++ PE LF + + D G Sbjct: 116 LSEEDTNILRQLFLSSAVSGSGKFSFQDLKQVLAKYA-DTIPEGPLKKLFVMVENDTKGR 174 Query: 80 IHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLN 139 + + + V + + + F D N +G ++ E + S+ Sbjct: 175 MSYITLVAVANDLAALVAD------FRKIDTNSNGTLSRKEFREHFVRLGFDKKSVQ--- 225 Query: 140 EDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 +F+ D++E + E+ Sbjct: 226 ----------DALFRYADEDESDDVGFSEYV 246 Score = 32.3 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 49/133 (36%), Gaps = 23/133 (17%) Query: 44 AREDFVKIYKQFFPFGS--PEDFANHLFTVF---DKDNNGFIHFEEFITVLSTTSRGTLE 98 ED Y + P E+ N L +F +G F++ VL+ + E Sbjct: 98 DLEDDASGYNRLRPSKPMLSEEDTNILRQLFLSSAVSGSGKFSFQDLKQVLAKYADTIPE 157 Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 L F + + + G +++ ++ + + ++ F+ +D Sbjct: 158 GPLKKLFVMVENDTKGRMSYITLVAVANDLAALVAD------------------FRKIDT 199 Query: 159 NEDGYITLDEFRE 171 N +G ++ EFRE Sbjct: 200 NSNGTLSRKEFRE 212 Score = 30.8 bits (68), Expect = 0.35, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 27/53 (50%) Query: 34 FLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFI 86 F SGQL++E+ K+ + S H F+V D D++ + ++EF+ Sbjct: 261 FADFDKSGQLSKEEVQKVLEDAHIPESARKKFEHQFSVVDVDDSKSLSYQEFV 313 >1O1A-B nrPDB Length = 145 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 27/110 (24%), Positives = 40/110 (36%), Gaps = 17/110 (15%) Query: 56 FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR-GTLEEKLSWAFELYDLNHDG 114 F EDF FTV D++ +G I ++ + R E+L + G Sbjct: 1 FDETEIEDFKEA-FTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEA----SG 55 Query: 115 YITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYI 164 I F LT+ K A PE + FK++D + G I Sbjct: 56 PINFTVFLTMFGEKLKG-----------ADPEDVIMGAFKVLDPDGKGSI 94 Score = 39.6 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 48/108 (44%), Gaps = 10/108 (9%) Query: 22 FDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGF 79 FD EI+ + + F + G + ++D + + + + + K+ +G Sbjct: 1 FDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMI----KEASGP 56 Query: 80 IHFEEFITVLSTTSRG-TLEEKLSWAFELYDLNHDGYITF---DEMLT 123 I+F F+T+ +G E+ + AF++ D + G I +E+LT Sbjct: 57 INFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLT 104 Score = 31.6 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 30/80 (37%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 SG + F+ ++ + PED F V D D G I +L+T E Sbjct: 54 SGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPE 113 Query: 100 KLSWAFELYDLNHDGYITFD 119 ++ + + + G + + Sbjct: 114 EIKNMWAAFPPDVAGNVDYK 133 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 17/30 (56%) Query: 142 EATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 + T K+ F ++D+N DG I D+ RE Sbjct: 2 DETEIEDFKEAFTVIDQNADGIIDKDDLRE 31 >3SIA-A nrPDB Length = 220 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 18/117 (15%) Query: 27 IQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS--PEDFANHLFTVFDKDNNGFIHFEE 84 I QW G RD SG L + + FP G A + +FD D NG I F E Sbjct: 53 IYQWFMGVDRD-RSGTLEINELMMGQ---FPGGIRLSPQTALRMMRIFDTDFNGHISFYE 108 Query: 85 FITVLSTTSRGTLEEKLSWAFELYDLN---HDGYITFDEMLTIVASVYKMMGSMVTL 138 F+ + + A+ L+ +N G + E+L + + + +L Sbjct: 109 FMAMYKF---------MELAYNLFVMNARARSGTLEPHEILPALQQLGFYINQRTSL 156 Score = 35.0 bits (79), Expect = 0.019, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 25/70 (35%), Gaps = 12/70 (17%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYI 164 F D + G + +E++ + L ++ ++ D + +G+I Sbjct: 57 FMGVDRDRSGTLEINELMMGQFPGGIRLSPQTAL------------RMMRIFDTDFNGHI 104 Query: 165 TLDEFREGSK 174 + EF K Sbjct: 105 SFYEFMAMYK 114 >2N8Y-A nrPDB Length = 153 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 43/115 (37%), Gaps = 17/115 (14%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRG-----TLEEKLSWAFELYDLNHDGYITFDEMLT 123 F FD+D++G + EEF L + E + + + D N G +TF + Sbjct: 16 FNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFID 75 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPS 178 ++ + + ++ DKN YIT+DE R D + Sbjct: 76 FMSR---------ETADTDTADQVMASFKILAGDKN---YITMDELRRELPPDQA 118 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 31/77 (40%), Gaps = 7/77 (9%) Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 + +F +D +H G + +E + S+ +G ++ E +I ++D N Sbjct: 11 EFRASFNHFDRDHSGTLGPEEFKACLISLGYDIG-------NDPQGEAEFARIMSIVDPN 63 Query: 160 EDGYITLDEFREGSKVD 176 G +T F + + Sbjct: 64 RLGVVTFQAFIDFMSRE 80 >4OKH-A nrPDB Length = 189 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 21/125 (16%), Positives = 42/125 (33%), Gaps = 25/125 (20%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 + + D D +G ++ +EF ++ F+ YD + G I EM V Sbjct: 60 MIALMDTDGSGKLNLQEF-----HHLWNKIKA-WQKIFKHYDTDQSGTINSYEMRNAVND 113 Query: 128 VYKMMGSMVTLNEDEATPEMRVK-----------------KIFKLMDKNEDGYITLD--E 168 + + + + + + F DK+ DG I L+ E Sbjct: 114 AGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLE 173 Query: 169 FREGS 173 + + + Sbjct: 174 WLQLT 178 Score = 31.6 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 21/125 (16%), Positives = 35/125 (28%), Gaps = 27/125 (21%) Query: 57 PFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS--------WAFELY 108 + ++F D + I +E VL+T + K L Sbjct: 6 QESEEQQQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALM 64 Query: 109 DLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE 168 D + G + E + + +KIFK D ++ G I E Sbjct: 65 DTDGSGKLNLQEFHHLWNKI------------------KAWQKIFKHYDTDQSGTINSYE 106 Query: 169 FREGS 173 R Sbjct: 107 MRNAV 111 Score = 26.2 bits (56), Expect = 8.9, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 30/80 (37%), Gaps = 5/80 (6%) Query: 90 STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRV 149 S+ +++ F+ + D I DE+ ++ +V + T Sbjct: 3 SSDQESEEQQQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLKTHG----FTLESC 57 Query: 150 KKIFKLMDKNEDGYITLDEF 169 + + LMD + G + L EF Sbjct: 58 RSMIALMDTDGSGKLNLQEF 77 >5TBY-E nrPDB Length = 166 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 41/120 (34%), Gaps = 17/120 (14%) Query: 54 QFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR-GTLEEKLSWAFELYDLNH 112 F ++F FT+ D++ +GFI + + R E++ + Sbjct: 19 SMFEQTQIQEFKEA-FTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEA---- 73 Query: 113 DGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 G I F LT+ K A PE + FK+ D G + D RE Sbjct: 74 PGPINFTVFLTMFGEKLKG-----------ADPEETILNAFKVFDPEGKGVLKADYVREM 122 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 57/152 (37%), Gaps = 19/152 (12%) Query: 19 STYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDN 76 + F++ +IQ++ + F + G + + D + + + + K+ Sbjct: 18 FSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMI----KEA 73 Query: 77 NGFIHFEEFITVLSTTSRG-TLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSM 135 G I+F F+T+ +G EE + AF+++D G + D + ++ Sbjct: 74 PGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLT--------- 124 Query: 136 VTLNEDEATPEMRVKKIFKLMDKNEDGYITLD 167 + E + V ++F + G + Sbjct: 125 ---TQAERFSKEEVDQMFAAFPPDVTGNLDYK 153 Score = 34.3 bits (77), Expect = 0.035, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 38/85 (44%) Query: 41 GQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEK 100 G + F+ ++ + PE+ + F VFD + G + + +L+T + +E+ Sbjct: 75 GPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEE 134 Query: 101 LSWAFELYDLNHDGYITFDEMLTIV 125 + F + + G + + ++ I+ Sbjct: 135 VDQMFAAFPPDVTGNLDYKNLVHII 159 >6AGH-A nrPDB Length = 339 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 39/117 (33%), Gaps = 9/117 (7%) Query: 78 GFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 G I + E++ +L+ ++ AF++ D + + I E + + K M Sbjct: 97 GLISYTEYLFLLTILTK--PHSGFHVAFKMLDTDGNEMIEKREFFKLQKIISKQDDLMTV 154 Query: 138 LNEDEATPEMRVKK-------IFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYD 187 + E VK+ + K + EFR + + I + Sbjct: 155 KTNETGYQEAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEFLQ 211 Score = 31.9 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 84 EFITVLS-TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 EF + T + L F+++DL+ D ++ +E L ++ + Sbjct: 290 EFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNRM 336 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 20/45 (44%) Query: 47 DFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLST 91 +F + K + + +F +FD D + + EEF+ VL Sbjct: 290 EFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKN 334 >1GJY-A nrPDB Length = 167 Score = 40.0 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 39/109 (35%), Gaps = 9/109 (8%) Query: 26 EIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEF 85 E + L SG + +F +++ + F FD D +G + +E Sbjct: 42 ETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW-------RQHFISFDSDRSGTVDPQEL 94 Query: 86 ITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 L+T + ++ + Y G ITFD+ + + + S Sbjct: 95 QKALTTMGFRLNPQTVNSIAKRYST--SGKITFDDYIACCVKLRALTDS 141 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 19/147 (12%), Positives = 46/147 (31%), Gaps = 24/147 (16%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFT----VFDKDNNGFIHFEEFITVLSTTSRG 95 GQ+ ++ + Q G + F + D+D +G + F EF + + + Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW 74 Query: 96 TLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKL 155 F +D + G + E+ + ++ + + + Sbjct: 75 RQH------FISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYSTS-------- 120 Query: 156 MDKNEDGYITLDEFREGSKVDPSIIGA 182 G IT D++ ++ + Sbjct: 121 ------GKITFDDYIACCVKLRALTDS 141 Score = 30.0 bits (66), Expect = 0.58, Method: Composition-based stats. Identities = 14/102 (13%), Positives = 31/102 (30%), Gaps = 23/102 (22%) Query: 76 NNGFIHFEEFITVLSTTS-----RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYK 130 +G I +E L+ + + E + D + G + F+E + A + Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNG 73 Query: 131 MMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 ++ F D + G + E ++ Sbjct: 74 ------------------WRQHFISFDSDRSGTVDPQELQKA 97 >5H53-B nrPDB Length = 146 Score = 40.0 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 38/109 (34%), Gaps = 17/109 (15%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSR-GTLEEKLSWAFELYDLNHDGYITFDEML 122 FTV D++ +G I E+ + R E+L + G I F L Sbjct: 6 EFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKEA----SGPINFTVFL 61 Query: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 T+ K A PE + FK++D G I +F E Sbjct: 62 TMFGEKLKG-----------ADPEDVITGAFKVLDPEGKGTI-KKQFLE 98 Score = 30.4 bits (67), Expect = 0.49, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 32/85 (37%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + SG + F+ ++ + PED F V D + G I + +L T Sbjct: 47 MMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELLITQCD 106 Query: 95 GTLEEKLSWAFELYDLNHDGYITFD 119 +E++ + + + G + + Sbjct: 107 RFSQEEIKNMWAAFSPDVGGNVDYK 131 >5H53-C nrPDB Length = 153 Score = 40.0 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 39/95 (41%), Gaps = 3/95 (3%) Query: 36 RDCPSGQLAREDFVKIYKQFFPFGSPEDFANHL--FTVFDKDNNGFIHFEEFITVLSTTS 93 + + ++ E F+ + + + + + VFDK+ NG + E VL+T Sbjct: 59 EEMNAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 118 Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 EE++ + +G I ++ + + S+ Sbjct: 119 EKMKEEEVEALMA-GQEDSNGCINYEAFVKHIMSI 152 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 41/112 (36%), Gaps = 11/112 (9%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 +D F ++D+ + I + VL ++ G + +E Sbjct: 9 QQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVL--------GNPSNEE 60 Query: 121 M--LTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 M I + M ++ N+D+ T E V + ++ DK +G + E R Sbjct: 61 MNAKKIEFEQFLPMLQAISNNKDQGTYEDFV-EGLRVFDKEGNGTVMGAELR 111 Score = 28.1 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 18/124 (14%), Positives = 46/124 (37%), Gaps = 6/124 (4%) Query: 21 YFDRREIQQWHKGFLRDCPSG--QLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN- 77 F + + ++ + FL +G ++ + + + + L +++ N Sbjct: 4 EFSKEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNA 63 Query: 78 GFIHFEEFITVLSTTSRGT---LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 I FE+F+ +L S E ++D +G + E+ ++A++ + M Sbjct: 64 KKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKE 123 Query: 135 MVTL 138 Sbjct: 124 EEVE 127 >1N2D-A nrPDB Length = 148 Score = 40.0 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 30/70 (42%), Gaps = 1/70 (1%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 EDF F VFDK++ G + + +L+ + ++ + +++ +G I + Sbjct: 80 AKTEDFVKA-FQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDY 138 Query: 119 DEMLTIVASV 128 + + V Sbjct: 139 KKFIEDVLRQ 148 Score = 36.6 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 35/105 (33%), Gaps = 5/105 (4%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 +FT+FDK G I + L + + N D + LT+ Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDII-----NADSSLRDASSLTLD 61 Query: 126 ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + + L+ K F++ DK G +++ + R Sbjct: 62 QITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLR 106 >3DTP-E nrPDB Length = 196 Score = 39.6 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 36/94 (38%), Gaps = 1/94 (1%) Query: 41 GQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEK 100 G + F+ I+ ED + F +FD+ +G E L+T +++ Sbjct: 104 GPINFTMFLTIFGDRIAGTDEEDVIVNAFNLFDE-GDGKCKEETLKRSLTTWGEKFSQDE 162 Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGS 134 + A ++ +G I + I+ K G+ Sbjct: 163 VDQALSEAPIDGNGLIDIKKFAQILTKGAKEEGA 196 Score = 35.8 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 35/132 (26%), Gaps = 28/132 (21%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 F + D+D +GFI + + R E++L G I F LT Sbjct: 58 EFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMVAEA----PGPINFTMFLT 113 Query: 124 IVASVYKMMGSMVTLNED------------------------EATPEMRVKKIFKLMDKN 159 I + E + V + + Sbjct: 114 IFGDRIAGTDEEDVIVNAFNLFDEGDGKCKEETLKRSLTTWGEKFSQDEVDQALSEAPID 173 Query: 160 EDGYITLDEFRE 171 +G I + +F + Sbjct: 174 GNGLIDIKKFAQ 185 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEM 147 ++ AF+L D + DG+I+ ++ + + + +G + T E ++ Sbjct: 57 QEFKEAFQLIDQDKDGFISKND----IRATFDSLGRLCTEQELDSMVAE 101 >6MI5-X nrPDB Length = 117 Score = 39.6 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 27/72 (37%), Gaps = 1/72 (1%) Query: 105 FELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKI-FKLMDKNEDGY 163 +D + DG I E L ++ + + D + RV + K +D + DG Sbjct: 9 IAAFDPDKDGTIDLKEALAAGSAAFDKLDPDKDGTLDAKELKGRVSEADLKKLDPDNDGT 68 Query: 164 ITLDEFREGSKV 175 + E+ + Sbjct: 69 LDKKEYLAAVEA 80 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 35/112 (31%), Gaps = 37/112 (33%) Query: 71 VFDKDNNGFIHFEEFITVLST------------TSRGTLEEKLSWA-FELYDLNHDGYIT 117 FD D +G I +E + S L+ ++S A + D ++DG + Sbjct: 11 AFDPDKDGTIDLKEALAAGSAAFDKLDPDKDGTLDAKELKGRVSEADLKKLDPDNDGTLD 70 Query: 118 FDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 E L V + FK + + DG I E Sbjct: 71 KKEYLAAVEAQ------------------------FKAANPDNDGTIDAREL 98 Score = 31.9 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 24/68 (35%), Gaps = 13/68 (19%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEK-------------LSWAFELYDLNHDGY 115 F D D +G + +E +S L+ + F+ + ++DG Sbjct: 33 FDKLDPDKDGTLDAKELKGRVSEADLKKLDPDNDGTLDKKEYLAAVEAQFKAANPDNDGT 92 Query: 116 ITFDEMLT 123 I E+ + Sbjct: 93 IDARELAS 100 >1SR6-C nrPDB Length = 156 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 5/91 (5%) Query: 42 QLAREDFVKIYKQFFPFGSPEDFANHL--FTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 L E+F+ Y+ FA+++ F FD++ GFI E VL+ +E Sbjct: 62 SLPFEEFLPAYEGLM-DCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGERLSDE 120 Query: 100 KLSWAFELYDLNHD--GYITFDEMLTIVASV 128 + +L DL D G + +++ + V + Sbjct: 121 DVDEIIKLTDLQEDLEGNVKYEDFVKKVMAG 151 Score = 31.6 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 24/107 (22%), Positives = 44/107 (41%), Gaps = 18/107 (16%) Query: 76 NNGFIHFEEFI---TVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 + FEEF+ L +GT + + AF+ +D G+I+ E+ ++ ++ Sbjct: 59 GEKSLPFEEFLPAYEGLMDCEQGTFADYME-AFKTFDREGQGFISGAELRHVLTALG--- 114 Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNED--GYITLDEFREGSKVDP 177 E + V +I KL D ED G + ++F + P Sbjct: 115 ---------ERLSDEDVDEIIKLTDLQEDLEGNVKYEDFVKKVMAGP 152 >3JBH-C nrPDB Length = 156 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 36/89 (40%), Gaps = 2/89 (2%) Query: 42 QLAREDFVKIYKQFFPFGSPEDFANHL--FTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 +L E+F+ I+ Q + + V+DK NG + E VL + + Sbjct: 61 KLTLEEFLPIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTDI 120 Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASV 128 + + D + DG++ ++ + + + Sbjct: 121 ECEEIMRVCDEDDDGFLKYEPFVKTIIAG 149 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 21/142 (14%), Positives = 49/142 (34%), Gaps = 28/142 (19%) Query: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 + A F ++D + G I + +L + + D + +T +E L Sbjct: 10 EKAREHFEIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKN-GGSDKRGEKKLTLEEFL 68 Query: 123 TIVASVYKMMG---------------------------SMVTLNEDEATPEMRVKKIFKL 155 I + + K + V L+ E ++ ++I ++ Sbjct: 69 PIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTDIECEEIMRV 128 Query: 156 MDKNEDGYITLDEFREGSKVDP 177 D+++DG++ + F + P Sbjct: 129 CDEDDDGFLKYEPFVKTIIAGP 150 >3BOW-B nrPDB Length = 184 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 47/141 (33%), Gaps = 28/141 (19%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + +G+L E+F ++ + ++ FD D +G I E Sbjct: 67 MDSDTTGKLGFEEFKYLWNNIKKW-------QGIYKRFDTDRSGTIGSNELPGAFEAAGF 119 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 + S Y + G + FD ++ + + M + F+ Sbjct: 120 HLNQHIYSMIIRRY-SDETGNMDFDNFISCLVRLDAMF------------------RAFR 160 Query: 155 LMDKNEDGYI--TLDEFREGS 173 +DKN G I + E+ + + Sbjct: 161 SLDKNGTGQIQVNIQEWLQLT 181 Score = 26.2 bits (56), Expect = 9.5, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 22/68 (32%), Gaps = 18/68 (26%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 + D + G + F+E + ++ K G I+K D + Sbjct: 61 RSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQG------------------IYKRFDTDRS 102 Query: 162 GYITLDEF 169 G I +E Sbjct: 103 GTIGSNEL 110 >4I5L-B nrPDB Length = 413 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 23/180 (12%), Positives = 56/180 (31%), Gaps = 14/180 (7%) Query: 4 KTSKLSKDDLTCLKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSP 61 + L +++ + + +F + F L + +D + Sbjct: 174 QNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLAR----HNDHALS 229 Query: 62 EDFANHLFTVFDKDN-----NGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYI 116 + +F+ G I + +F+ L + + + F DL+ DG + Sbjct: 230 TKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGAL 289 Query: 117 TFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVD 176 + E+ + + SM ++ + K +G ITL + + + Sbjct: 290 SMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKP---RTEGKITLQDLKRCKLAN 346 >4MEW-A nrPDB Length = 356 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 23/180 (12%), Positives = 56/180 (31%), Gaps = 14/180 (7%) Query: 4 KTSKLSKDDLTCLKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSP 61 + L +++ + + +F + F L + +D + Sbjct: 166 QNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLAR----HNDHALS 221 Query: 62 EDFANHLFTVFDKDN-----NGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYI 116 + +F+ G I + +F+ L + + + F DL+ DG + Sbjct: 222 TKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGAL 281 Query: 117 TFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVD 176 + E+ + + SM ++ + K +G ITL + + + Sbjct: 282 SMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKP---RTEGKITLQDLKRCKLAN 338 >3DF0-A nrPDB Length = 714 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 21/117 (17%), Positives = 41/117 (35%), Gaps = 23/117 (19%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 + + D+D +G + +EF + + +K + D++ G + EM + Sbjct: 580 MVDMLDEDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEMRKALEE 633 Query: 128 VYKMMGSMVTLN------EDEATPE-----------MRVKKIFKLMDKNEDGYITLD 167 + + +DE + + KIFK +D G I LD Sbjct: 634 AGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLD 690 Score = 27.3 bits (59), Expect = 3.6, Method: Composition-based stats. Identities = 15/104 (14%), Positives = 31/104 (29%), Gaps = 26/104 (25%) Query: 77 NGFIHFEEFITVLSTTSRGTLEEKL--------SWAFELYDLNHDGYITFDEMLTIVASV 128 + I E T+L + K ++ D + G + E + + Sbjct: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI 604 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 K +KI++ +D + G + E R+ Sbjct: 605 QKY------------------QKIYREIDVDRSGTMNSYEMRKA 630 >2FCE-A nrPDB Length = 70 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 30/70 (42%), Gaps = 1/70 (1%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 EDF F VFDK++ G + + +L+ + ++ + +++ +G I + Sbjct: 2 AKTEDFVKA-FQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDY 60 Query: 119 DEMLTIVASV 128 + + V Sbjct: 61 KKFIEDVLRQ 70 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 29/72 (40%), Gaps = 12/72 (16%) Query: 104 AFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGY 163 AF+++D G ++ ++ ++ + E + V ++ K ++ + +G Sbjct: 10 AFQVFDKESTGKVSVGDLRYMLTGLG------------EKLTDAEVDELLKGVEVDSNGE 57 Query: 164 ITLDEFREGSKV 175 I +F E Sbjct: 58 IDYKKFIEDVLR 69 >3A8R-A nrPDB Length = 179 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 56/150 (37%), Gaps = 11/150 (7%) Query: 32 KGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNN---GFIHFEEFITV 88 K F + G L R F K ++FA +F + + +E Sbjct: 32 KRFNQLQVDGVLLRSRFGKCIGMDG----SDEFAVQMFDSLARKRGIVKQVLTKDELKDF 87 Query: 89 LSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMR 148 + + +L F++ D N DG +T +E+ I+A + S L++ + + Sbjct: 88 YEQLTDQGFDNRLRTFFDMVDKNADGRLTAEEVKEIIA----LSASANKLSKIKERADEY 143 Query: 149 VKKIFKLMDKNEDGYITLDEFREGSKVDPS 178 I + +D GYI +++ PS Sbjct: 144 TALIMEELDPTNLGYIEMEDLEALLLQSPS 173 >5MKE-A nrPDB Length = 968 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 23/56 (41%), Gaps = 2/56 (3%) Query: 76 NNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 G ++F+E L +G + ++ F YD + D +T E + + K Sbjct: 732 GGGKLNFDELRQDLK--GKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKE 785 >1WY9-A nrPDB Length = 147 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 25/77 (32%) Query: 72 FDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 FD + NG I +L +L + ++ + L ++ Sbjct: 57 FDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSGSEETFSYSDFLRMMLGKRSA 116 Query: 132 MGSMVTLNEDEATPEMR 148 + M+ + E++ R Sbjct: 117 ILRMILMYEEKNKEHKR 133 >6D1W-A nrPDB Length = 740 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 23/56 (41%), Gaps = 2/56 (3%) Query: 76 NNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 G ++F+E L +G + ++ F YD + D +T E + + K Sbjct: 680 GGGKLNFDELRQDLK--GKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKE 733 >3I5I-C nrPDB Length = 159 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 38/88 (43%), Gaps = 4/88 (4%) Query: 45 REDFVKIYKQFF--PFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS 102 E+ + IY++ G+ D F FD++ G I E VL E++ + Sbjct: 65 LEEILPIYEEMSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKMLGERITEDQCN 124 Query: 103 WAFELYDL--NHDGYITFDEMLTIVASV 128 F D+ + DG I +++++ V + Sbjct: 125 DIFTFCDIREDIDGNIKYEDLMKKVMAG 152 Score = 35.0 bits (79), Expect = 0.021, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 38/114 (33%), Gaps = 12/114 (10%) Query: 63 DFANHLFTVFDK-DN-NGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 + +F +FD D +G + + +L E ++ H G E Sbjct: 9 EEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQ--------HGGTKKMGE 60 Query: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 + + + M ++D T + FK D+ G I+ E R K Sbjct: 61 KAYKLEEILPIYEEM--SSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLK 112 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 14/91 (15%) Query: 89 LSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMR 148 +S+ GT ++ AF+ +D G I+ E + +V KM+G +T E + Sbjct: 75 MSSKDTGTAADEFMEAFKTFDREGQGLISSAE----IRNVLKMLGERIT--------EDQ 122 Query: 149 VKKIFKLMD--KNEDGYITLDEFREGSKVDP 177 IF D ++ DG I ++ + P Sbjct: 123 CNDIFTFCDIREDIDGNIKYEDLMKKVMAGP 153 >2I18-A nrPDB Length = 64 Score = 36.6 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 16/74 (21%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE 160 L ++L D++ DG +T +E+ + E +++ K D N Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKK---------------HGIEKVAEQVMK-ADANG 50 Query: 161 DGYITLDEFREGSK 174 DGYITL+EF E S Sbjct: 51 DGYITLEEFLEFSL 64 Score = 33.9 bits (76), Expect = 0.040, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 L+ + D D +G + EE + + E++ A D N DGYIT +E L Sbjct: 10 LYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKA----DANGDGYITLEEFLEF 62 >2OS8-B nrPDB Length = 157 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 35/95 (36%), Gaps = 15/95 (15%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 FT+ D++ +GFI + + S+ R +++L+ + G + F L+ Sbjct: 20 EMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEA----PGPLNFTMFLS 75 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 I + E ++ F + D+ Sbjct: 76 IFSDKL-----------SGTDSEETIRNAFGMFDE 99 Score = 28.1 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 L++ P G L F+ I+ E+ + F +FD+ + ++ E +L Sbjct: 61 LKEAP-GPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGD 119 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 ++++ F+ + G + + ++ Sbjct: 120 NFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIK 150 Score = 27.3 bits (59), Expect = 3.6, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 18/26 (69%) Query: 147 MRVKKIFKLMDKNEDGYITLDEFREG 172 +K+ F ++D+N DG+I +++ +E Sbjct: 19 QEMKEAFTMIDQNRDGFIDINDLKEM 44 >2KGR-A nrPDB Length = 111 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 28/59 (47%), Gaps = 2/59 (3%) Query: 67 HLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 LF DK +G + + T+L + +L+ + L D++ DG +T +E + + Sbjct: 18 QLFNSHDKTMSGHLTGPQARTIL--MQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAM 74 Score = 31.6 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 30/74 (40%), Gaps = 14/74 (18%) Query: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 K F +D G++T + TI+ + P+ ++ I+ L D + Sbjct: 15 KYRQLFNSHDKTMSGHLTGPQARTILMQ--------------SSLPQAQLASIWNLSDID 60 Query: 160 EDGYITLDEFREGS 173 +DG +T +EF Sbjct: 61 QDGKLTAEEFILAM 74 Score = 31.2 bits (69), Expect = 0.27, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 19/54 (35%), Gaps = 3/54 (5%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTS 93 SG L I P+ ++ + D D +G + EEFI + Sbjct: 28 SGHLTGPQARTI---LMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLID 78 >3TS5-B nrPDB Length = 161 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 35/95 (36%), Gaps = 15/95 (15%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 FT+ D++ +GFI + + S+ R +++L+ + G + F L+ Sbjct: 24 EMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEA----PGPLNFTMFLS 79 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 I + E ++ F + D+ Sbjct: 80 IFSDKL-----------SGTDSEETIRNAFGMFDE 103 Score = 28.1 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 L++ P G L F+ I+ E+ + F +FD+ + ++ E +L Sbjct: 65 LKEAP-GPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGD 123 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 ++++ F+ + G + + ++ Sbjct: 124 NFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIK 154 Score = 27.3 bits (59), Expect = 3.7, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 18/26 (69%) Query: 147 MRVKKIFKLMDKNEDGYITLDEFREG 172 +K+ F ++D+N DG+I +++ +E Sbjct: 23 QEMKEAFTMIDQNRDGFIDINDLKEM 48 >1Q80-A nrPDB Length = 174 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 48/146 (32%), Gaps = 29/146 (19%) Query: 40 SGQLAREDFVKIYKQFFPFGSPEDF-----ANHLFTVFDK-----DNNGFIHFEEFITVL 89 G + R DF + ++F + + L V+D I FI + Sbjct: 20 DGAITRMDFESMAERFAKESEMKAEHAKVLMDSLTGVWDNFLTAVAGGKGIDETTFINSM 79 Query: 90 STTSRGT-----LEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEAT 144 + +E L F D N D I+ DE M+G T+ Sbjct: 80 KEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDEYGIFFG----MLGLDKTMAPAS-- 133 Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFR 170 F +D N DG ++L+EF Sbjct: 134 --------FDAIDTNNDGLLSLEEFV 151 Score = 29.2 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 34/111 (30%), Gaps = 40/111 (36%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKM--------------------------- 131 +K+ F D + DG IT + ++ K Sbjct: 6 QKMKTYFNRIDFDKDGAITRMDFESMAERFAKESEMKAEHAKVLMDSLTGVWDNFLTAVA 65 Query: 132 -------------MGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 M MV E ++ E + F+ +D NED I+ DE+ Sbjct: 66 GGKGIDETTFINSMKEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDEY 116 Score = 26.5 bits (57), Expect = 6.6, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 23/62 (37%), Gaps = 3/62 (4%) Query: 30 WHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL 89 + ++R+++ + G + A F D +N+G + EEF+ Sbjct: 98 LFFRAVDTNEDNNISRDEYGIFFGML---GLDKTMAPASFDAIDTNNDGLLSLEEFVIAG 154 Query: 90 ST 91 S Sbjct: 155 SD 156 >2LVV-A nrPDB Length = 226 Score = 35.8 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 23/59 (38%), Gaps = 1/59 (1%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLE-EKLSWAFELYDLNHDGYITFDEM 121 +F DKD + + +EF L ++ + F D N G +TFDE Sbjct: 134 ELTVMFDTMDKDGSLLLELQEFKEALPKLKEWGVDITDATTVFNEIDTNGSGVVTFDEF 192 Score = 33.9 bits (76), Expect = 0.041, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 41/138 (29%), Gaps = 35/138 (25%) Query: 67 HLFTVFDKDNNGFIHFEEFITVL-STTSRGTLEEKLSWAF-ELYDLNHD--------GYI 116 LF FD + G + F E + L +D D G Sbjct: 55 ELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGEE 114 Query: 117 TFDEM---------------LTIVASVYKMMGSMVTLNEDEATPEMRVKK---------- 151 E LT++ GS++ ++ ++K+ Sbjct: 115 DLVEFLEFRLMLCYIYDIFELTVMFDTMDKDGSLLLELQEFKEALPKLKEWGVDITDATT 174 Query: 152 IFKLMDKNEDGYITLDEF 169 +F +D N G +T DEF Sbjct: 175 VFNEIDTNGSGVVTFDEF 192 Score = 33.5 bits (75), Expect = 0.058, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 24/60 (40%), Gaps = 1/60 (1%) Query: 26 EIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEF 85 E+ +D L ++F + + +G A +F D + +G + F+EF Sbjct: 134 ELTVMFDTMDKDGSL-LLELQEFKEALPKLKEWGVDITDATTVFNEIDTNGSGVVTFDEF 192 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 28/83 (33%), Gaps = 2/83 (2%) Query: 103 WAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDG 162 F+ +D N G + F E+L + K+ L + + K + + G Sbjct: 55 ELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKV--KGVG 112 Query: 163 YITLDEFREGSKVDPSIIGALNL 185 L EF E + I L Sbjct: 113 EEDLVEFLEFRLMLCYIYDIFEL 135 Score = 29.6 bits (65), Expect = 0.94, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 134 SMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 + +A + R ++FK D N G + E +G Sbjct: 38 RCAIPRDKDAESKSRRIELFKQFDTNGTGKLGFREVLDGC 77 >4OCI-A nrPDB Length = 146 Score = 35.4 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 33/81 (40%) Query: 43 LAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS 102 ++ E F + Q +D V DKD GFI E +LST +++++ Sbjct: 57 MSYELFTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEIT 116 Query: 103 WAFELYDLNHDGYITFDEMLT 123 F ++ G + D+ + Sbjct: 117 DLFTFMGIDEQGVVKVDDFIN 137 Score = 34.3 bits (77), Expect = 0.036, Method: Composition-based stats. Identities = 19/147 (12%), Positives = 48/147 (32%), Gaps = 47/147 (31%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTS-------------------------- 93 + F +FD D +G++ EF +++ Sbjct: 3 KHNEDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMETSAIASTYNSNSKVRGMSYELF 62 Query: 94 ---------RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEAT 144 + ++++ A + D + G+I E+ I++++ + Sbjct: 63 TSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIG------------DNM 110 Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFRE 171 + + +F M +E G + +D+F Sbjct: 111 EQKEITDLFTFMGIDEQGVVKVDDFIN 137 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 20/36 (55%) Query: 147 MRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGA 182 +K+ F L D + DGY+TL+EF +V ++ Sbjct: 6 EDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMET 41 >2EC6-B nrPDB Length = 133 Score = 35.4 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 38/104 (36%), Gaps = 15/104 (14%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 FT+ D++ +GFI + S+ R +++L+ + G + F L+ Sbjct: 3 EMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPDDKELTAMLKEA----PGPLNFTMFLS 58 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLD 167 I + E ++ F + D++ + ++ Sbjct: 59 IFSDKL-----------SGTDSEETIRNAFGMFDEDATKKLNIE 91 Score = 31.2 bits (69), Expect = 0.26, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 L++ P G L F+ I+ E+ + F +FD+D ++ E +L Sbjct: 44 LKEAP-GPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDLLENMGD 102 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 ++++ F+ + G + + ++ Sbjct: 103 NFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIK 133 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 37/94 (39%), Gaps = 6/94 (6%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + G + D + + ++ L K+ G ++F F+++ S Sbjct: 11 IDQNRDGFIDINDLKEEFSSLGRTPDDKELTAML-----KEAPGPLNFTMFLSIFSDKLS 65 Query: 95 GT-LEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 GT EE + AF ++D + + + + ++ + Sbjct: 66 GTDSEETIRNAFGMFDEDATKKLNIEYIKDLLEN 99 Score = 26.2 bits (56), Expect = 8.7, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 18/25 (72%) Query: 147 MRVKKIFKLMDKNEDGYITLDEFRE 171 +K+ F ++D+N DG+I +++ +E Sbjct: 2 QEMKEAFTMIDQNRDGFIDINDLKE 26 >1BOD-A nrPDB Length = 74 Score = 35.4 bits (80), Expect = 0.017, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 32/77 (41%), Gaps = 10/77 (12%) Query: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 E+L FE YD DG S ++ + T + ++F+ +DK Sbjct: 5 EELKGIFEKYDKEGDGQ----------LSKEELKLLLQTEFPSLLKGMSTLDELFEELDK 54 Query: 159 NEDGYITLDEFREGSKV 175 N DG ++ +EF+ K Sbjct: 55 NGDGEVSFEEFQVLVKK 71 Score = 29.6 bits (65), Expect = 0.87, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 29/72 (40%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 E++ + + ++ E + + +F + LF DK+ +G + F Sbjct: 3 SPEELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEVSF 62 Query: 83 EEFITVLSTTSR 94 EEF ++ S+ Sbjct: 63 EEFQVLVKKISQ 74 Score = 29.2 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLE--EKLSWAFELYDLNHDGYIT 117 + +F +DK+ +G + EE +L T L+ L FE D N DG ++ Sbjct: 2 KSPEELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEVS 61 Query: 118 FDEMLTIVASVYK 130 F+E +V + + Sbjct: 62 FEEFQVLVKKISQ 74 >4NSC-A nrPDB Length = 401 Score = 35.0 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 40/103 (38%), Gaps = 7/103 (6%) Query: 78 GFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM---LTIVASVYKMMGS 134 G I F ++I + + S ++ AF+++DLN DG + +E +I+ S M Sbjct: 127 GLISFSDYIFLTTVLSTPQRNFEI--AFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMR 184 Query: 135 MVTLNEDEATPEMRVKKIFK--LMDKNEDGYITLDEFREGSKV 175 T + + + G +T+ F E + Sbjct: 185 HRDRPTTGNTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRK 227 Score = 33.9 bits (76), Expect = 0.048, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 39/103 (37%), Gaps = 13/103 (12%) Query: 79 FIHFEEFITVLSTTSRGTLEEKL-SWAFELYDLNHDGYITFDE---------MLTIVASV 128 F+ E+F+ ++ + L + + +D I+ + T+ Sbjct: 71 FMTPEDFVRSITPNEKQPEHLGLDQYIIKRFDGK---KISQEREKFADEGSIFYTLGECG 127 Query: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 + L +TP+ + FK+ D N DG + ++EF + Sbjct: 128 LISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQ 170 Score = 31.2 bits (69), Expect = 0.28, Method: Composition-based stats. Identities = 14/101 (13%), Positives = 38/101 (37%), Gaps = 13/101 (12%) Query: 2 GAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPS------------GQLAREDFV 49 K + + + K+ +E++ + FL++ L + Sbjct: 264 SKKLTAMQRQLKKHFKEGKGLTFQEVENFF-TFLKNINDVDTALSFYHMAGASLDKVTMQ 322 Query: 50 KIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLS 90 ++ + + + +F +FD D NG + +EF++++ Sbjct: 323 QVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMK 363 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 14/23 (60%) Query: 105 FELYDLNHDGYITFDEMLTIVAS 127 F L+D + +G ++ E ++I+ Sbjct: 342 FALFDCDGNGELSNKEFVSIMKQ 364 Score = 28.5 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 28/75 (37%), Gaps = 3/75 (4%) Query: 23 DRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHF 82 +R + F G ++ D++ + +P+ F +FD + +G + Sbjct: 109 EREKFADEGSIFYTLGECGLISFSDYIFLTTVL---STPQRNFEIAFKMFDLNGDGEVDM 165 Query: 83 EEFITVLSTTSRGTL 97 EEF V S T Sbjct: 166 EEFEQVQSIIRSQTS 180 Score = 27.7 bits (60), Expect = 3.0, Method: Composition-based stats. Identities = 8/40 (20%), Positives = 16/40 (40%), Gaps = 2/40 (5%) Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALN 184 + +F L D + +G ++ EF K ++ L Sbjct: 334 SDHVCDVVFALFDCDGNGELSNKEFVSIMK--QRLMRGLE 371 >1CB1-A nrPDB Length = 78 Score = 34.6 bits (78), Expect = 0.024, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 2/74 (2%) Query: 23 DRREIQQWHKGFL-RDCPSGQLAREDFVKIYKQFFP-FGSPEDFANHLFTVFDKDNNGFI 80 E++ + + ++ QL++E+ ++ + FP + LF DK+ +G + Sbjct: 5 SPAELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDGEV 64 Query: 81 HFEEFITVLSTTSR 94 FEEF ++ S+ Sbjct: 65 SFEEFQVLVKKISQ 78 Score = 33.9 bits (76), Expect = 0.040, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 32/74 (43%), Gaps = 13/74 (17%) Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 +A + D N ++ +E+ ++ + + + + +F+ +DKN D Sbjct: 15 KYAAKEGDPN---QLSKEELKQLIQAEFPSLLKGP----------RTLDDLFQELDKNGD 61 Query: 162 GYITLDEFREGSKV 175 G ++ +EF+ K Sbjct: 62 GEVSFEEFQVLVKK 75 Score = 30.4 bits (67), Expect = 0.46, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 16/30 (53%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYK 130 L F+ D N DG ++F+E +V + + Sbjct: 49 LDDLFQELDKNGDGEVSFEEFQVLVKKISQ 78 >2LUC-A nrPDB Length = 105 Score = 34.6 bits (78), Expect = 0.025, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 27/78 (34%), Gaps = 11/78 (14%) Query: 99 EKLSWAFELYDLNHDGY---ITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKL 155 E L F+ Y DGY ++ E L+ + + + ++ K Sbjct: 15 ESLIAVFQKY-AGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDP-------GVLDRMMKK 66 Query: 156 MDKNEDGYITLDEFREGS 173 +D N DG + EF Sbjct: 67 LDTNSDGQLDFSEFLNLI 84 Score = 31.9 bits (71), Expect = 0.18, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 24/58 (41%), Gaps = 4/58 (6%) Query: 36 RDCPSGQLAREDFVKIYK----QFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL 89 +D + L++ +F+ F + + D +++G + F EF+ ++ Sbjct: 27 KDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFLNLI 84 Score = 31.6 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 26/61 (42%), Gaps = 6/61 (9%) Query: 74 KDN-NGFIHFEEFITVLSTTSRGTLEEK-----LSWAFELYDLNHDGYITFDEMLTIVAS 127 KD N + EF++ ++T + + L + D N DG + F E L ++ Sbjct: 27 KDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFLNLIGG 86 Query: 128 V 128 + Sbjct: 87 L 87 >1F4Q-A nrPDB Length = 165 Score = 34.6 bits (78), Expect = 0.026, Method: Composition-based stats. Identities = 16/128 (12%), Positives = 40/128 (31%), Gaps = 9/128 (7%) Query: 26 EIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEF 85 E + L +G++ F +++ + F D+D +G + E Sbjct: 40 ETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKEN-------FMTVDQDGSGTVEHHEL 92 Query: 86 ITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATP 145 + + L+ + Y + +G I FD+ + + + + + Sbjct: 93 RQAIGLMGYRLSPQTLTTIVKRY--SKNGRIFFDDYVACCVKLRALTDFFKKRDHLQQGS 150 Query: 146 EMRVKKIF 153 + F Sbjct: 151 ADFIYDDF 158 Score = 33.9 bits (76), Expect = 0.045, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 33/103 (32%), Gaps = 23/103 (22%) Query: 76 NNGFIHFEEFITVLSTTSRGTLE-----EKLSWAFELYDLNHDGYITFDEMLTIVASVYK 130 +G + EE L+ + E + D +H G + F+ + A++ Sbjct: 12 QDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNA 71 Query: 131 MMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 K+ F +D++ G + E R+ Sbjct: 72 ------------------WKENFMTVDQDGSGTVEHHELRQAI 96 >1QX2-A nrPDB Length = 76 Score = 34.6 bits (78), Expect = 0.027, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 36/79 (45%), Gaps = 12/79 (15%) Query: 99 EKLSWAFELYDLN--HDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 E++ AFE++ I+ +E+ ++ ++ + ++ + ++ + + Sbjct: 5 EEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMS----------TLDEMIEEV 54 Query: 157 DKNEDGYITLDEFREGSKV 175 DKN DG ++ +EF K Sbjct: 55 DKNGDGEVSFEEFLVMMKK 73 Score = 34.3 bits (77), Expect = 0.035, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Query: 23 DRREIQQWHKGFL-RDCPSGQLAREDFVKIYKQFFP-FGSPEDFANHLFTVFDKDNNGFI 80 EI+ + F ++ Q+++E+ + + P + + DK+ +G + Sbjct: 3 SPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGEV 62 Query: 81 HFEEFITVLSTTSR 94 FEEF+ ++ S+ Sbjct: 63 SFEEFLVMMKKISQ 76 Score = 33.9 bits (76), Expect = 0.044, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 31/75 (41%), Gaps = 4/75 (5%) Query: 60 SPEDFANHLFTVFD-KDNN-GFIHFEEFITVLSTTSRGTLE--EKLSWAFELYDLNHDGY 115 + F VF K+ + I EE V+ T L+ L E D N DG Sbjct: 2 KSPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGE 61 Query: 116 ITFDEMLTIVASVYK 130 ++F+E L ++ + + Sbjct: 62 VSFEEFLVMMKKISQ 76 >2G2B-A nrPDB Length = 150 Score = 34.3 bits (77), Expect = 0.030, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 26/77 (33%) Query: 72 FDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 FD + NG I +L +L ++ + L ++ Sbjct: 60 FDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKRSA 119 Query: 132 MGSMVTLNEDEATPEMR 148 + M+ + E++A + + Sbjct: 120 ILKMILMYEEKAREKEK 136 >1GGW-A nrPDB Length = 140 Score = 34.3 bits (77), Expect = 0.033, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 38/107 (35%), Gaps = 17/107 (15%) Query: 66 NHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F++FD+ G I +L + +++ + ++ L ++ Sbjct: 8 KQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAEITEIESTLPA----EVDMEQFLQVL 63 Query: 126 AS--VYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + M G PE V K F++ DK+ G I + E R Sbjct: 64 NRPNGFDMPG----------DPEEFV-KGFQVFDKDATGMIGVGELR 99 >2L50-A nrPDB Length = 102 Score = 34.3 bits (77), Expect = 0.035, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 3/63 (4%) Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDE 142 +E +LS T +KL + D NHDG I+FDE T++ + + ++ E + Sbjct: 43 KELNHMLSDTGNRKAADKL---IQNLDANHDGRISFDEYWTLIGGITGPIAKLIHEQEQQ 99 Query: 143 ATP 145 ++ Sbjct: 100 SSS 102 Score = 32.7 bits (73), Expect = 0.092, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 19/55 (34%), Gaps = 7/55 (12%) Query: 115 YITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 I+ ++ M + K+ + +D N DG I+ DE+ Sbjct: 31 KISKSSFREMLQKELNHM-------LSDTGNRKAADKLIQNLDANHDGRISFDEY 78 Score = 26.9 bits (58), Expect = 5.1, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 19/45 (42%) Query: 45 REDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL 89 RE K A+ L D +++G I F+E+ T++ Sbjct: 38 REMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEYWTLI 82 >6AGI-A nrPDB Length = 382 Score = 33.9 bits (76), Expect = 0.049, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 27/67 (40%), Gaps = 8/67 (11%) Query: 42 QLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKL 101 + +++F + N +F +FD D + + ++EFI ++ ++L Sbjct: 322 SIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMK--------DRL 373 Query: 102 SWAFELY 108 F Y Sbjct: 374 HRGFRGY 380 Score = 32.7 bits (73), Expect = 0.10, Method: Composition-based stats. Identities = 25/133 (18%), Positives = 47/133 (35%), Gaps = 17/133 (12%) Query: 42 QLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKL 101 ++ EDF I ++ + F ++ ++ I F+EF + + E Sbjct: 255 TISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKG--ITFDEFRSFFQFLNNL---EDF 309 Query: 102 SWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNED 161 + A +Y+ I DE V + S V +FK+ D ++D Sbjct: 310 AIALNMYNF-ASRSIGQDEFKRAVYVATGLKFSP-----------HLVNTVFKIFDVDKD 357 Query: 162 GYITLDEFREGSK 174 ++ EF K Sbjct: 358 DQLSYKEFIGIMK 370 Score = 31.2 bits (69), Expect = 0.27, Method: Composition-based stats. Identities = 11/65 (16%), Positives = 25/65 (38%), Gaps = 2/65 (3%) Query: 78 GFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVT 137 G I + E++ +L ++ AF ++D + + + E L + K Sbjct: 86 GVISYTEYLFLLCILTK--PHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREI 143 Query: 138 LNEDE 142 ++E Sbjct: 144 KGDEE 148 Score = 26.9 bits (58), Expect = 5.1, Method: Composition-based stats. Identities = 7/34 (20%), Positives = 16/34 (47%) Query: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS 102 F +FD D N + +EF+ + + + ++ Sbjct: 111 FNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIK 144 >1B7T-Y nrPDB Length = 156 Score = 33.5 bits (75), Expect = 0.051, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 37/104 (35%), Gaps = 15/104 (14%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 F++ D D +GF+ E+ + R +++L+ + G + F L+ Sbjct: 19 EMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAMLKEA----PGPLNFTMFLS 74 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLD 167 I + E ++ F + D+ E + ++ Sbjct: 75 IFSDKL-----------SGTDSEETIRNAFAMFDEQETKKLNIE 107 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 35/92 (38%), Gaps = 2/92 (2%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 L++ P G L F+ I+ E+ + F +FD+ ++ E +L Sbjct: 60 LKEAP-GPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGD 118 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 ++++ F+ + G + + ++ Sbjct: 119 NFNKDEMRMTFKEAPVEG-GKFDYVKFTAMIK 149 Score = 27.3 bits (59), Expect = 4.6, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 49/112 (43%), Gaps = 8/112 (7%) Query: 19 STYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDN 76 T +++IQ+ + F + G +++ED I +Q ++ L K+ Sbjct: 9 LTKLPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAML-----KEA 63 Query: 77 NGFIHFEEFITVLSTTSRGT-LEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 G ++F F+++ S GT EE + AF ++D + + + ++ + Sbjct: 64 PGPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLEN 115 >6DU8-A nrPDB Length = 805 Score = 33.5 bits (75), Expect = 0.058, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 24/63 (38%), Gaps = 1/63 (1%) Query: 80 IHFEEFITVLSTTSRGTLE-EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTL 138 I FE+F L E +L+ F +D + + + E + + + ++ T Sbjct: 616 IQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTE 675 Query: 139 NED 141 E Sbjct: 676 IEK 678 Score = 26.5 bits (57), Expect = 6.8, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 14/41 (34%), Gaps = 3/41 (7%) Query: 47 DFVKIYKQFFPFGSPEDFANHL---FTVFDKDNNGFIHFEE 84 F G E L FT FD+D N + +E Sbjct: 617 QFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKE 657 >5X2E-A nrPDB Length = 80 Score = 33.5 bits (75), Expect = 0.060, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 24/56 (42%), Gaps = 2/56 (3%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 +F DKD I + E ++ + + W +L+D ++ G IT + + Sbjct: 6 IFVSIDKDGTNVISYPELEQYVAENNLDPSMVE-KWK-QLFDPDNTGSITLETFCS 59 Score = 26.9 bits (58), Expect = 5.8, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 29/75 (38%), Gaps = 14/75 (18%) Query: 104 AFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGY 163 F D + I++ E+ VA N + + + K++F D + G Sbjct: 6 IFVSIDKDGTNVISYPELEQYVA-----------ENNLDPSMVEKWKQLF---DPDNTGS 51 Query: 164 ITLDEFREGSKVDPS 178 ITL+ F + P+ Sbjct: 52 ITLETFCSKLGLKPA 66 >1NSH-A nrPDB Length = 101 Score = 33.5 bits (75), Expect = 0.064, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 26/78 (33%), Gaps = 11/78 (14%) Query: 99 EKLSWAFELYDLNHDG---YITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKL 155 E L F+ Y DG ++ E L+ + + + ++ K Sbjct: 11 ESLIAVFQKY-AGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDP-------GVLDRMMKK 62 Query: 156 MDKNEDGYITLDEFREGS 173 +D N DG + EF Sbjct: 63 LDLNSDGQLDFQEFLNLI 80 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 5/55 (9%) Query: 79 FIHFEEFITVLSTTSRGTLEEK-----LSWAFELYDLNHDGYITFDEMLTIVASV 128 + EF++ ++T + + L + DLN DG + F E L ++ + Sbjct: 29 TLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGGL 83 Score = 31.2 bits (69), Expect = 0.26, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 25/58 (43%), Gaps = 4/58 (6%) Query: 36 RDCPSGQLAREDFVKIYK----QFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL 89 +D S L++ +F+ F + + D +++G + F+EF+ ++ Sbjct: 23 KDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLI 80 >1QLS-A nrPDB Length = 99 Score = 33.1 bits (74), Expect = 0.068, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 26/61 (42%), Gaps = 6/61 (9%) Query: 74 KDNNGF-IHFEEFITVLSTTSRGTLEEK-----LSWAFELYDLNHDGYITFDEMLTIVAS 127 +D N I EF+ ++T + + L + DL+ DG + F E L ++ Sbjct: 25 RDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFLNLIGG 84 Query: 128 V 128 + Sbjct: 85 L 85 Score = 31.9 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 9/62 (14%), Positives = 20/62 (32%), Gaps = 7/62 (11%) Query: 112 HDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 ++ I+ E L + + + ++ K +D + DG + EF Sbjct: 28 NNTKISKTEFLIFMNTELAAFTQNQKDP-------GVLDRMMKKLDLDSDGQLDFQEFLN 80 Query: 172 GS 173 Sbjct: 81 LI 82 Score = 30.0 bits (66), Expect = 0.67, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 26/58 (44%), Gaps = 4/58 (6%) Query: 36 RDCPSGQLAREDFVKIYK----QFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL 89 RD + ++++ +F+ F + + D D++G + F+EF+ ++ Sbjct: 25 RDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFLNLI 82 >1DFK-Y nrPDB Length = 139 Score = 33.1 bits (74), Expect = 0.068, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 37/104 (35%), Gaps = 15/104 (14%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 F++ D D +GF+ E+ + R +++L+ + G + F L+ Sbjct: 8 EMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAMLKEA----PGPLNFTMFLS 63 Query: 124 IVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLD 167 I + E ++ F + D+ E + ++ Sbjct: 64 IFSDKL-----------SGTDSEETIRNAFAMFDEQETKKLNIE 96 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 35/92 (38%), Gaps = 2/92 (2%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 L++ P G L F+ I+ E+ + F +FD+ ++ E +L Sbjct: 49 LKEAP-GPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGD 107 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 ++++ F+ + G + + ++ Sbjct: 108 NFNKDEMRMTFKEAPVEG-GKFDYVKFTAMIK 138 >4C0K-A nrPDB Length = 423 Score = 33.1 bits (74), Expect = 0.069, Method: Composition-based stats. Identities = 19/159 (11%), Positives = 48/159 (30%), Gaps = 12/159 (7%) Query: 15 CLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDK 74 ++ T ++ + + K L + ++ F + + V K Sbjct: 3 EEQELTSACKKSLVRIFKI-CDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVIQK 61 Query: 75 D-----NNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 + N + + F+ + + E + GY EM Sbjct: 62 NVPDGIYNDAVTLKGFLFLHCLFIQRGRNETTWAVLRRF-----GYNDQLEMCQEYLRPP 116 Query: 130 KMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE 168 + + E + + +F+ D++ DG ++ +E Sbjct: 117 LKIPPG-SSTELSHRGQQFLIAVFERYDRDGDGALSPEE 154 Score = 27.3 bits (59), Expect = 3.7, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 23/59 (38%), Gaps = 3/59 (5%) Query: 135 MVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE---FREGSKVDPSIIGALNLYDGLI 190 M+ E + + + +IFK+ D + D + E F+ P L+ +I Sbjct: 1 MMEEQELTSACKKSLVRIFKICDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVI 59 >1NP8-A nrPDB Length = 159 Score = 33.1 bits (74), Expect = 0.075, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 29/89 (32%), Gaps = 6/89 (6%) Query: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 + V D D G + FEEF + + +K ++ +D + G I +E+ + Sbjct: 59 MVAVMDSDTTGKLGFEEFKYLWNNI------KKWQGIYKRFDTDRSGTIGSNELPGAFEA 112 Query: 128 VYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 + + + F Sbjct: 113 AGFHLNQHIYSMIIRRYSDETGNMDFDNF 141 Score = 32.7 bits (73), Expect = 0.097, Method: Composition-based stats. Identities = 16/97 (16%), Positives = 33/97 (34%), Gaps = 8/97 (8%) Query: 35 LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSR 94 + +G+L E+F ++ + ++ FD D +G I E Sbjct: 63 MDSDTTGKLGFEEFKYLWNNIKKW-------QGIYKRFDTDRSGTIGSNELPGAFEAAGF 115 Query: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 + S Y + G + FD ++ + + M Sbjct: 116 HLNQHIYSMIIRRY-SDETGNMDFDNFISCLVRLDAM 151 >4I5K-A nrPDB Length = 285 Score = 33.1 bits (74), Expect = 0.080, Method: Composition-based stats. Identities = 23/173 (13%), Positives = 53/173 (30%), Gaps = 10/173 (5%) Query: 4 KTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPED 63 +T L +++ + + YF + F ++ S Sbjct: 92 QTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTD--HDLYISQADLSRYNDQASSSR 149 Query: 64 FANHLFTVFDKDN-----NGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 +F+ G + + +F+ L + + + F D++ DG ++ Sbjct: 150 IIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSM 209 Query: 119 DEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 E+ + M +M ++ + K DG ITL + + Sbjct: 210 YELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPA---VDGKITLRDLKR 259 >1KQV-A nrPDB Length = 79 Score = 32.7 bits (73), Expect = 0.090, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 18/27 (66%) Query: 149 VKKIFKLMDKNEDGYITLDEFREGSKV 175 + ++F+ +DKN DG ++ +EF+ K Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKK 76 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 29/74 (39%), Gaps = 2/74 (2%) Query: 23 DRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFI 80 E++ + + P+ E + + +F + LF DK+ +G + Sbjct: 6 SPEELKGIFEKYAAKEGDPNQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEV 65 Query: 81 HFEEFITVLSTTSR 94 FEEF ++ S+ Sbjct: 66 SFEEFQVLVKKISQ 79 Score = 28.1 bits (61), Expect = 2.3, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 16/30 (53%) Query: 101 LSWAFELYDLNHDGYITFDEMLTIVASVYK 130 L FE D N DG ++F+E +V + + Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKKISQ 79 >5W1A-B nrPDB Length = 155 Score = 32.7 bits (73), Expect = 0.10, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 36/89 (40%), Gaps = 6/89 (6%) Query: 42 QLAREDFVKIYKQFFPFGSP---EDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLE 98 ++ ++F+ IY Q EDF ++DK+ NG + E L + Sbjct: 60 KIKLDEFLPIYSQVKKEKEQGCYEDFIE-CLKLYDKEENGTMLLAELQHALLALGESLDD 118 Query: 99 EKLSWAFEL-YD-LNHDGYITFDEMLTIV 125 E++ F D + +G+I + L + Sbjct: 119 EQVETLFADCMDPEDDEGFIPYSPFLARM 147 >5NRM-B nrPDB Length = 66 Score = 32.3 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 23/60 (38%) Query: 73 DKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 D D NG I+ +F + + + + DLN D I ++ + + M+ Sbjct: 4 DVDGNGSINSIDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSININDFAIMRMYLLGMI 63 >5CUY-A nrPDB Length = 414 Score = 32.3 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 28/69 (40%), Gaps = 1/69 (1%) Query: 53 KQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNH 112 K F + + LF+ FD + G++ ++ V R + + + Sbjct: 69 KDDFTQPMIKKIMSRLFSAFDVTHLGYLTPDKVEEVCRYLGRNMSDGDVKAMKAEINA-I 127 Query: 113 DGYITFDEM 121 DG++TF++ Sbjct: 128 DGHVTFEKF 136 >5LXV-B nrPDB Length = 88 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 21/49 (42%), Gaps = 5/49 (10%) Query: 73 DKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEM 121 D D +G + + I + G E FE DLN DG I D++ Sbjct: 27 DLDGDGEVDVFDLILMRKAVENGDTER-----FEAADLNCDGVIDSDDL 70 >5NRK-B nrPDB Length = 68 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 22/60 (36%) Query: 73 DKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 D D NG I+ +F + + + + DLN D I + + + M+ Sbjct: 4 DVDGNGSININDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSINSLDFAIMRMYLLGMI 63 >2MHH-A nrPDB Length = 96 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 24/60 (40%), Gaps = 2/60 (3%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 D + + + F+E+ L RG + + F YD++ D + +E + + Sbjct: 20 IQEALAHADANADQHLDFDEWRQELKC--RGHADADIEAVFAKYDVDGDRVLDAEEQMKM 77 >2KHN-A nrPDB Length = 121 Score = 31.9 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 18/41 (43%) Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNL 185 P+ + +I+ L D N DG + EF K+ + L Sbjct: 64 PQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQL 104 Score = 30.0 bits (66), Expect = 0.59, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 17/38 (44%) Query: 55 FFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 FF G P+ ++ + D +N+G + EF + Sbjct: 58 FFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLI 95 >1ZFS-A nrPDB Length = 93 Score = 31.9 bits (71), Expect = 0.18, Method: Composition-based stats. Identities = 7/48 (14%), Positives = 20/48 (41%) Query: 45 REDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 ++ F D + + D++ +G + F+EF+ +++ Sbjct: 34 KDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAAL 81 Score = 31.2 bits (69), Expect = 0.28, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 20/45 (44%) Query: 126 ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 + ++ + ++ D V KI K +D+N DG + EF Sbjct: 31 KELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFV 75 Score = 26.2 bits (56), Expect = 9.8, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 28/61 (45%), Gaps = 6/61 (9%) Query: 74 KDNNGF-IHFEEFITVLSTTSRGTLE-----EKLSWAFELYDLNHDGYITFDEMLTIVAS 127 K+ + + + +E +L T L+ + + + D N DG + F E + +VA+ Sbjct: 21 KEGDKYKLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAA 80 Query: 128 V 128 + Sbjct: 81 L 81 >1SNL-A nrPDB Length = 103 Score = 31.6 bits (70), Expect = 0.23, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 33/77 (42%), Gaps = 4/77 (5%) Query: 105 FELYDLNHDGYITFDEMLTIV----ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNE 160 F L+D+N DG + E+ + VY + E E + + K +D N+ Sbjct: 26 FILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVDTNQ 85 Query: 161 DGYITLDEFREGSKVDP 177 D +TL+EF ++ Sbjct: 86 DRLVTLEEFLASTQRKE 102 >1OHZ-B nrPDB Length = 60 Score = 31.6 bits (70), Expect = 0.24, Method: Composition-based stats. Identities = 9/60 (15%), Positives = 25/60 (41%), Gaps = 2/60 (3%) Query: 73 DKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 D + +G I+ + + + R A D++ +G I ++L + + +++ Sbjct: 3 DVNGDGTINSTDLTMLKRSVLRAITLTD--DAKARADVDKNGSINSTDVLLLSRYLLRVI 60 >1NUB-A nrPDB Length = 229 Score = 31.2 bits (69), Expect = 0.26, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 15/70 (21%) Query: 101 LSWAFELYDLNH-DGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 + W F D + DGY++ E+ + A + M + F+ D + Sbjct: 157 VHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTT--------------RFFETCDLD 202 Query: 160 EDGYITLDEF 169 D YI LDE+ Sbjct: 203 NDKYIALDEW 212 >2D58-A nrPDB Length = 107 Score = 31.2 bits (69), Expect = 0.27, Method: Composition-based stats. Identities = 9/67 (13%), Positives = 20/67 (29%) Query: 72 FDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 FD + NG I +L +L ++ + L ++ Sbjct: 41 FDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKRSA 100 Query: 132 MGSMVTL 138 + M+ + Sbjct: 101 ILKMILM 107 >6DS2-B nrPDB Length = 114 Score = 31.2 bits (69), Expect = 0.32, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 20/61 (32%), Gaps = 6/61 (9%) Query: 115 YITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 + E +V + E E ++ I + +D N D ++ +EF Sbjct: 31 TLNQGEFKELVRKDLQNFLK------KENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMA 84 Query: 175 V 175 Sbjct: 85 R 85 Score = 30.4 bits (67), Expect = 0.44, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 27/67 (40%), Gaps = 6/67 (8%) Query: 42 QLAREDFVKIYKQFFP-----FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT 96 L + +F ++ ++ E H+ D + + + FEEFI +++ + Sbjct: 31 TLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARLTWA- 89 Query: 97 LEEKLSW 103 EK+ Sbjct: 90 SHEKMHE 96 >5VT9-A nrPDB Length = 152 Score = 31.2 bits (69), Expect = 0.32, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 48/109 (44%), Gaps = 6/109 (5%) Query: 18 QSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFAN-HLFTVFDKDN 76 Q + E + + F G+++ D + + +Q G +A+ F DN Sbjct: 10 QEALEEMVEADEMYARFNARASGGKVSTGDAMILARQL---GLAPSYADKQAFEEKSGDN 66 Query: 77 NGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 + F++F+ ST +E+ L AF +D++ GY+T +M I+ Sbjct: 67 LDYASFQKFV-GTSTHPEDNIED-LVEAFAYFDVSKHGYLTRKQMGNIL 113 >5C5V-A nrPDB Length = 342 Score = 30.8 bits (68), Expect = 0.36, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 26/64 (40%), Gaps = 1/64 (1%) Query: 58 FGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYIT 117 + + LF+ FD + G++ ++ V R + + + DG++T Sbjct: 2 QPMIKKIMSRLFSAFDVTHLGYLTPDKVEEVCRYLGRNMSDGDVKAMKAEINA-IDGHVT 60 Query: 118 FDEM 121 F++ Sbjct: 61 FEKF 64 >6EMI-A nrPDB Length = 532 Score = 30.8 bits (68), Expect = 0.38, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 20/66 (30%), Gaps = 1/66 (1%) Query: 34 FLRDCPSGQLAREDFVKIYKQFFPFGSP-EDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 FL D P L F K F + F KDN+ I +EF L Sbjct: 301 FLTDMPDTLLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNDSIITRKEFQEGLKVF 360 Query: 93 SRGTLE 98 E Sbjct: 361 FPNVSE 366 Score = 28.1 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 9/19 (47%), Positives = 11/19 (57%) Query: 156 MDKNEDGYITLDEFREGSK 174 K+ D IT EF+EG K Sbjct: 340 FSKDNDSIITRKEFQEGLK 358 >5CUU-A nrPDB Length = 414 Score = 30.4 bits (67), Expect = 0.48, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 25/66 (37%), Gaps = 1/66 (1%) Query: 56 FPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY 115 F + +F+ FD G++ + + R E+ + + DG+ Sbjct: 71 FTLSMEKRVMARMFSAFDVTQLGYLEERKIEHMCKYLGRVMNEDDVKQMKSEINA-IDGH 129 Query: 116 ITFDEM 121 ITF++ Sbjct: 130 ITFEKF 135 >5G6V-A nrPDB Length = 324 Score = 30.4 bits (67), Expect = 0.49, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 37/102 (36%), Gaps = 8/102 (7%) Query: 71 VFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHD----GYITFDEMLTIVA 126 D G I F E T T+EE+L + F + + G ++ +E T Sbjct: 181 QIDMWGVGCI-FYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNY 239 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDE 168 Y+ + ++ + K+ + +N I+ ++ Sbjct: 240 PKYRAEALLSHAPRLDSDGADLLTKLLQFEGRN---RISAED 278 >2VTG-A nrPDB Length = 150 Score = 30.4 bits (67), Expect = 0.51, Method: Composition-based stats. Identities = 8/69 (11%), Positives = 22/69 (31%) Query: 72 FDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 FD +N G I ++ ++ I++ + + ++ Sbjct: 59 FDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYRDFVNMMLGKRSA 118 Query: 132 MGSMVTLNE 140 + +V + E Sbjct: 119 VLKLVMMFE 127 >3FSR-A nrPDB Length = 352 Score = 30.0 bits (66), Expect = 0.58, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 16/37 (43%), Gaps = 2/37 (5%) Query: 38 CPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDK 74 CP G+L E + + F+ P H+F FD Sbjct: 295 CPGGRLRMERLIDLV--FYKRVDPSKLVTHVFRGFDN 329 >3FPC-A nrPDB Length = 352 Score = 30.0 bits (66), Expect = 0.58, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 16/37 (43%), Gaps = 2/37 (5%) Query: 38 CPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDK 74 CP G+L E + + F+ P H+F FD Sbjct: 295 CPGGRLRMERLIDLV--FYKRVDPSKLVTHVFRGFDN 329 >1YKF-A nrPDB Length = 352 Score = 30.0 bits (66), Expect = 0.58, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 16/37 (43%), Gaps = 2/37 (5%) Query: 38 CPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDK 74 CP G+L E + + F+ P H+F FD Sbjct: 295 CPGGRLRMERLIDLV--FYKRVDPSKLVTHVFRGFDN 329 >2AUC-A nrPDB Length = 126 Score = 30.0 bits (66), Expect = 0.61, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 4/92 (4%) Query: 34 FLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTS 93 F +G+L ED ++ S D + ++ D+ + + E++T+ Sbjct: 4 FNTKSSNGKLRIEDASHNARKLGLAPSSTDE-KKIRDLY-GDSLTYEQYLEYLTMC-VHD 60 Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 R +EE L F +D N G++T ++M I+ Sbjct: 61 RDNMEE-LIKMFSHFDNNSSGFLTKNQMKNIL 91 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 28/67 (41%) Query: 42 QLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKL 101 L E +++ + +F+ FD +++GF+ + +L+T E++ Sbjct: 44 SLTYEQYLEYLTMCVHDRDNMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQEA 103 Query: 102 SWAFELY 108 + A + Sbjct: 104 NDALNAF 110 >2JXC-A nrPDB Length = 100 Score = 30.0 bits (66), Expect = 0.62, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Query: 57 PFGSPEDFANHLFTVFDKDN--NGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDG 114 P+ + +FD + NGF+ ++ VL + + L +EL D++HDG Sbjct: 6 PWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVL--LNSKLPVDILGRVWELSDIDHDG 63 Query: 115 YITFDEMLTIVASVY 129 + DE + VY Sbjct: 64 MLDRDEFAVAMFLVY 78 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 15/29 (51%) Query: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGS 173 P + ++++L D + DG + DEF Sbjct: 46 PVDILGRVWELSDIDHDGMLDRDEFAVAM 74 >6QAA-A nrPDB Length = 557 Score = 30.0 bits (66), Expect = 0.66, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 21/66 (31%), Gaps = 1/66 (1%) Query: 34 FLRDCPSGQLAREDFVKIYKQFFPFGSP-EDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 FL D P L F K F + F KDNN I +EF L Sbjct: 326 FLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF 385 Query: 93 SRGTLE 98 G E Sbjct: 386 FPGVSE 391 >5KU1-A nrPDB Length = 424 Score = 29.6 bits (65), Expect = 0.77, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 23/57 (40%), Gaps = 5/57 (8%) Query: 139 NEDEATPE--MRVKKIFKLMDKNEDGYITLDE---FREGSKVDPSIIGALNLYDGLI 190 E E P + +IFK+ D++ DG + E F+ P AL ++ Sbjct: 1 EEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVV 57 Score = 26.5 bits (57), Expect = 6.2, Method: Composition-based stats. Identities = 6/21 (28%), Positives = 13/21 (61%) Query: 101 LSWAFELYDLNHDGYITFDEM 121 L+ F++ D ++DG + E+ Sbjct: 13 LTRIFKISDQDNDGTLNDAEL 33 >2MJW-B nrPDB Length = 94 Score = 29.6 bits (65), Expect = 0.81, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 25/63 (39%), Gaps = 4/63 (6%) Query: 37 DCPSGQLAREDFVKIYKQ----FFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 + + L + + + ++ F G +D + L D + + + F EFI ++ Sbjct: 22 EGSTQTLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAI 81 Query: 93 SRG 95 + Sbjct: 82 TSA 84 Score = 27.7 bits (60), Expect = 2.8, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 23/56 (41%), Gaps = 7/56 (12%) Query: 115 YITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFR 170 +T E+ ++ K + + +D+ V K+ K +D N D + EF Sbjct: 27 TLTKGELKVLME---KELPGFLQSGKDKDA----VDKLLKDLDANGDAQVDFSEFI 75 >1DJX-A nrPDB Length = 624 Score = 29.6 bits (65), Expect = 0.86, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 27/79 (34%), Gaps = 12/79 (15%) Query: 90 STTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRV 149 S R L+ + D N D + F E+ + + + + Sbjct: 2 SMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVD------------DGYA 49 Query: 150 KKIFKLMDKNEDGYITLDE 168 +KIF+ D ++ + +E Sbjct: 50 RKIFRECDHSQTDSLEDEE 68 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 30/92 (32%), Gaps = 15/92 (16%) Query: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 + DK+ + ++F+E L + + F D + + +E+ T Sbjct: 13 IHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQTDSLEDEEIETF 72 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLM 156 YKM+ T + + F+ Sbjct: 73 ----YKML-----------TQRAEIDRAFEEA 89 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 6/29 (20%), Positives = 13/29 (44%) Query: 146 EMRVKKIFKLMDKNEDGYITLDEFREGSK 174 + + + DKN+D + E ++ K Sbjct: 10 QHWIHSCLRKADKNKDNKMNFKELKDFLK 38 >2L0P-A nrPDB Length = 94 Score = 29.2 bits (64), Expect = 0.95, Method: Composition-based stats. Identities = 7/48 (14%), Positives = 20/48 (41%) Query: 45 REDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 +E F D + + D++ +G + F+E++ +++ Sbjct: 35 KELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAAL 82 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 8/22 (36%), Positives = 13/22 (59%) Query: 149 VKKIFKLMDKNEDGYITLDEFR 170 V K+ K +D+N DG + E+ Sbjct: 55 VDKVMKELDENGDGEVDFQEYV 76 >5CSF-A nrPDB Length = 95 Score = 29.2 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 8/48 (16%), Positives = 22/48 (45%) Query: 126 ASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 + + +++ + ++ +E + V K+ + +D + DG EF Sbjct: 34 SELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFV 81 Score = 27.7 bits (60), Expect = 2.9, Method: Composition-based stats. Identities = 8/50 (16%), Positives = 20/50 (40%), Gaps = 4/50 (8%) Query: 42 QLAREDFVKIYKQ----FFPFGSPEDFANHLFTVFDKDNNGFIHFEEFIT 87 +L + + ++ F ++ + + D D +G F+EF+ Sbjct: 30 KLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMA 79 >2K60-A nrPDB Length = 150 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 24/44 (54%) Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVD 176 GS + +EDE V+ I KLMD + +G + ++E E + D Sbjct: 1 GSHMASSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLRED 44 >2JQ6-A nrPDB Length = 139 Score = 28.9 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 24/58 (41%), Gaps = 5/58 (8%) Query: 117 TFDEMLTIVASVYKMMGSMVTLNEDEAT-----PEMRVKKIFKLMDKNEDGYITLDEF 169 I ++ + G + N + P + KI+KL D ++DG + +EF Sbjct: 49 DKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 106 >3H4S-E nrPDB Length = 135 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 27/95 (28%), Gaps = 4/95 (4%) Query: 60 SPEDFANHLFTVFDKDNNGF---IHFEEFITVLSTTS-RGTLEEKLSWAFELYDLNHDGY 115 E+F + L F + I E G +E DL+ DG Sbjct: 34 DVEEFVSELCKGFSLLADPERHLITAESLRRNSGILGIEGMSKEDAQGMVREGDLDGDGA 93 Query: 116 ITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVK 150 + E ++ + M ++A + Sbjct: 94 LNQTEFCVLMVRLSPEMMEDAETWLEKALTQELCN 128 >2WCE-A nrPDB Length = 95 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 29/86 (33%), Gaps = 12/86 (13%) Query: 93 SRGTLEEKLS---WAFELYDLNHDGY--ITFDEMLTIVASVYKMMGSMVTLNEDEATPEM 147 LEE L F Y + + ++ E+ ++ + + Sbjct: 3 GSTKLEEHLEGIVNIFHQYSVRKGHFDTLSKGELKQLLTKELANTIKNIKD-------KA 55 Query: 148 RVKKIFKLMDKNEDGYITLDEFREGS 173 + +IF+ +D N+D + EF Sbjct: 56 VIDEIFQGLDANQDEQVDFQEFISMV 81 Score = 27.3 bits (59), Expect = 3.8, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 24/65 (36%) Query: 72 FDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 FD + G + + +T + + F+ D N D + F E +++VA K Sbjct: 28 FDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMVAIALKA 87 Query: 132 MGSMV 136 Sbjct: 88 AHYHT 92 Score = 27.3 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 26/64 (40%), Gaps = 1/64 (1%) Query: 32 KGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLST 91 KG G+L ++ K + + +F D + + + F+EFI++++ Sbjct: 25 KGHFDTLSKGEL-KQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMVAI 83 Query: 92 TSRG 95 + Sbjct: 84 ALKA 87 >2KLD-A nrPDB Length = 123 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 23/56 (41%), Gaps = 2/56 (3%) Query: 76 NNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 G ++F+E L +G + ++ F YD + D +T E + + K Sbjct: 59 GGGKLNFDELRQDLK--GKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKE 112 >1QJT-A nrPDB Length = 99 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 22/62 (35%) Query: 31 HKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLS 90 ++ + R +G R + G P+ ++ + D D G + +EF L Sbjct: 13 YEKYYRQVEAGNTGRVLALDAAAFLKKSGLPDLILGKIWDLADTDGKGVLSKQEFFVALR 72 Query: 91 TT 92 Sbjct: 73 LV 74 >2KFH-A nrPDB Length = 105 Score = 28.5 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 24/58 (41%), Gaps = 5/58 (8%) Query: 117 TFDEMLTIVASVYKMMGSMVTLNEDEAT-----PEMRVKKIFKLMDKNEDGYITLDEF 169 I ++ + G + N + P + KI+KL D ++DG + +EF Sbjct: 15 DKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 72 >4YBH-B nrPDB Length = 92 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 22/56 (39%) Query: 73 DKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 DK +E I T + +++ E D N D + F E +T + ++ Sbjct: 27 DKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFLGAL 82 Score = 26.9 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 10/60 (16%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Query: 42 QLAREDFVKIYKQFFPFGS--PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEE 99 L++++ ++ ++ GS + L D++ + ++F+E++T L + E Sbjct: 30 TLSKKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFLGALALIYNEA 89 >6J79-A nrPDB Length = 871 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 28/61 (45%), Gaps = 3/61 (4%) Query: 8 LSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP-EDFAN 66 +S+D LK++T I+ + F+R+ GQ++RE F + + + E+ Sbjct: 29 MSQDLSEALKEATKEVH--IRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIE 86 Query: 67 H 67 Sbjct: 87 R 87 >1SRA-A nrPDB Length = 151 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 15/70 (21%) Query: 101 LSWAFELYDLNH-DGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 + W F D + DGY++ E+ + A + M + F+ D + Sbjct: 79 VHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTT--------------RFFETCDLD 124 Query: 160 EDGYITLDEF 169 D YI LDE+ Sbjct: 125 NDKYIALDEW 134 >1C07-A nrPDB Length = 95 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 29/81 (35%), Gaps = 2/81 (2%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITF 118 + + + +F DKD +GF+ E + G L+ + L D G ++ Sbjct: 6 PAEKAKYDEIFLKTDKDMDGFVSGLEVREIF--LKTGLPSTLLAHIWSLCDTKDCGKLSK 63 Query: 119 DEMLTIVASVYKMMGSMVTLN 139 D+ + + + + Sbjct: 64 DQFALAFHLISQKLIKGIDPP 84 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 14/72 (19%) Query: 98 EEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 + K F D + DG+++ E+ I P + I+ L D Sbjct: 9 KAKYDEIFLKTDKDMDGFVSGLEVREIF--------------LKTGLPSTLLAHIWSLCD 54 Query: 158 KNEDGYITLDEF 169 + G ++ D+F Sbjct: 55 TKDCGKLSKDQF 66 >4L9O-A nrPDB Length = 349 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 8/22 (36%), Positives = 15/22 (68%) Query: 161 DGYITLDEFREGSKVDPSIIGA 182 DG I++ EF++G ++P +I Sbjct: 182 DGKISIVEFKDGGALEPIVIQG 203 >4PCW-A nrPDB Length = 94 Score = 28.1 bits (61), Expect = 2.3, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 18/44 (40%) Query: 52 YKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRG 95 ++Q D + D D+N I F EF+ ++ ++ Sbjct: 43 FRQILKNPDDPDMVDVFMDHLDIDHNKKIDFTEFLLMVFKLAQA 86 >1KFU-L nrPDB Length = 699 Score = 28.1 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 24/166 (14%), Positives = 49/166 (29%), Gaps = 28/166 (16%) Query: 16 LKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFF-PFGSPEDFANHLFTVFDK 74 L ST+ ++ + F Q ++ ++F +D LF Sbjct: 483 LVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGVRRLFAQL-A 541 Query: 75 DNNGFIHFEEFITVLSTTSRGTLEEKL--------SWAFELYDLNHDGYITFDEMLTIVA 126 + I E T+L + K ++ D + G + E + Sbjct: 542 GEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWT 601 Query: 127 SVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 + K +KI++ +D + G + E R+ Sbjct: 602 KIQKY------------------QKIYREIDVDRSGTMNSYEMRKA 629 >2M7L-A nrPDB Length = 144 Score = 28.1 bits (61), Expect = 2.6, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 33/95 (34%), Gaps = 7/95 (7%) Query: 64 FANHLFTVFDKDNNGFIHFEEFITVLSTTSR------GTLEEKLSWAFELYDLNHDGYIT 117 F FD +++G + EF + LS+ G + + + +G ++ Sbjct: 13 EFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQYDAIYNNVTKGENG-VS 71 Query: 118 FDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKI 152 FD + + S LNE +T I Sbjct: 72 FDNYVQYMKEKNDENPSPEQLNEIFSTIAAGKDSI 106 >4G7U-A nrPDB Length = 267 Score = 27.7 bits (60), Expect = 3.0, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 28/61 (45%), Gaps = 3/61 (4%) Query: 8 LSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP-EDFAN 66 +S+D LK++T I+ + F+R+ GQ++RE F + + + E+ Sbjct: 9 MSQDLSEALKEATKEVH--IRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIE 66 Query: 67 H 67 Sbjct: 67 R 67 >5ZDH-A nrPDB Length = 646 Score = 27.7 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 37/107 (34%), Gaps = 9/107 (8%) Query: 60 SPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY---- 115 S + A L + D +G + + V+ T R ++ E+L+ + D + Sbjct: 114 SVRELAPILRQMIDSAGSGNVVNYDPSNVIMLTGRASVVERLTEVIQRVDHAGNRTEEVI 173 Query: 116 ----ITFDEMLTIVASVYKMMGSMVTLNED-EATPEMRVKKIFKLMD 157 + E+ ++ S+ K G + + R + D Sbjct: 174 PLDNASASEIARVLESLTKNSGENQPATLKSQIVADERTNSVIVSGD 220 >5HYD-A nrPDB Length = 99 Score = 27.7 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 20/61 (32%), Gaps = 7/61 (11%) Query: 115 YITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSK 174 ++ E+ ++ S V KI + +D N+D + +EF Sbjct: 28 KLSKGELKLLLQRELTEFLSCQKET-------QLVDKIVQDLDANKDNEVDFNEFVVMVA 80 Query: 175 V 175 Sbjct: 81 A 81 Score = 27.3 bits (59), Expect = 3.8, Method: Composition-based stats. Identities = 5/45 (11%), Positives = 16/45 (35%) Query: 48 FVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 + +F + + D + + + F EF+ +++ Sbjct: 38 LQRELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVAAL 82 >5NPF-A nrPDB Length = 798 Score = 27.7 bits (60), Expect = 3.3, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 30/74 (40%), Gaps = 1/74 (1%) Query: 103 WAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDG 162 + D ++DG + + + M G+ ++I K++ K+ + Sbjct: 553 DKLKEMDKDNDGIPDNEGIPDQTYDTWSMKGTSAYCGSLWLAALKAAQEIGKVL-KDNEA 611 Query: 163 YITLDEFREGSKVD 176 YI +E+ + ++ + Sbjct: 612 YIKYNEWYKIAQQN 625 >5JMV-A nrPDB Length = 348 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 6/68 (8%) Query: 113 DGYITFDEMLTIVASVYKM-MGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 DG + F+ TI+ K + + T +K+ F+++DKN I L F + Sbjct: 26 DGEVLFN--KTIMYKPPKQGINPREAADHHAETFPKLIKEAFEVVDKN---EIDLIAFSQ 80 Query: 172 GSKVDPSI 179 G + PS+ Sbjct: 81 GPGLGPSL 88 >2L5Y-A nrPDB Length = 150 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 23/44 (52%) Query: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVD 176 GS + E++ ++ I K MD ++DG I ++E E + D Sbjct: 1 GSHMASTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIRED 44 >4MEC-A nrPDB Length = 232 Score = 27.7 bits (60), Expect = 3.5, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 28/61 (45%), Gaps = 3/61 (4%) Query: 8 LSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSP-EDFAN 66 +S+D LK++T I+ + F+R+ GQ++RE F + + + E+ Sbjct: 9 MSQDLSEALKEATKEVH--IRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIE 66 Query: 67 H 67 Sbjct: 67 R 67 >3B97-A nrPDB Length = 433 Score = 27.7 bits (60), Expect = 3.5, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 33/93 (35%), Gaps = 3/93 (3%) Query: 67 HLFTVFDKDNNGFIHFEEFIT--VLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 H +FD N + + F + + + A EL D + Y+ + Sbjct: 6 HAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKG-VSKA 64 Query: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMD 157 V + K + + + T + ++ K+ MD Sbjct: 65 VEHINKTIAPALVSKKLNVTEQEKIDKLMIEMD 97 >5VP3-A nrPDB Length = 206 Score = 27.3 bits (59), Expect = 3.8, Method: Composition-based stats. Identities = 8/49 (16%), Positives = 18/49 (36%), Gaps = 2/49 (4%) Query: 81 HFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 EE T++ +E F+ D + G + E++ + + Sbjct: 144 DVEELKTMMKAFD--VPQEAAYTFFQKADTDKTGKLERPELVHLFRKFW 190 Score = 26.5 bits (57), Expect = 6.6, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 17/45 (37%), Gaps = 3/45 (6%) Query: 46 EDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLS 90 E+ + K F P++ A F D D G + E + + Sbjct: 146 EELKTMMKAF---DVPQEAAYTFFQKADTDKTGKLERPELVHLFR 187 >2KQ6-A nrPDB Length = 78 Score = 27.3 bits (59), Expect = 4.0, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 23/56 (41%), Gaps = 2/56 (3%) Query: 76 NNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKM 131 G ++F+E L +G + ++ F YD + D +T E + + K Sbjct: 13 GGGKLNFDELRQDLK--GKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKE 66 >5X2G-A nrPDB Length = 835 Score = 27.3 bits (59), Expect = 4.3, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 42/114 (36%), Gaps = 6/114 (5%) Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHD--GYITFDEMLTIVASVYKMMGSMVTLNE 140 ++ + + E KL A YDLN + ++ E + +K + + L Sbjct: 356 DDLNEIAKDITLIKDEIKLKKALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLVTPLML 415 Query: 141 DEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVD----PSIIGALNLYDGLI 190 + + ++ + NED L F E D P ++ A+ Y ++ Sbjct: 416 EGKKYDEACNELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKVL 469 >5AHV-F nrPDB Length = 268 Score = 27.3 bits (59), Expect = 4.4, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 25/70 (35%), Gaps = 7/70 (10%) Query: 76 NNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSM 135 NNG +EE+++++S + E + L D + DE I+ + + Sbjct: 123 NNGTFEYEEYVSLVSVSDPDEGYETILDLMSLQD-------SLDEFSQIIFASIQSERRN 175 Query: 136 VTLNEDEATP 145 P Sbjct: 176 TECKISALIP 185 >5W2O-A nrPDB Length = 439 Score = 27.3 bits (59), Expect = 4.5, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 14/32 (43%), Gaps = 1/32 (3%) Query: 58 FGSPEDFANHLFTVFDKDNNGFIHFEEFITVL 89 + D FDKD +GF+ F E ++ Sbjct: 239 MSTRNDEPERASRPFDKDRDGFV-FGEAGALM 269 >2QPT-A nrPDB Length = 550 Score = 27.3 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 17/42 (40%), Gaps = 5/42 (11%) Query: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS 102 P ++ + D D +G + EEF + +E KL Sbjct: 489 PNSVLGRIWKLSDVDRDGMLDDEEF-----ALASHLIEAKLE 525 >6EHA-A nrPDB Length = 288 Score = 26.9 bits (58), Expect = 5.1, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 26/61 (42%), Gaps = 3/61 (4%) Query: 8 LSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFP-FGSPEDFAN 66 + +D LK++T + + F+R+ GQ+ R+ F + + + + E+ Sbjct: 9 MPQDLSEALKEATKEVHTQAENA--EFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIE 66 Query: 67 H 67 Sbjct: 67 R 67 >1ZQ1-C nrPDB Length = 633 Score = 26.9 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 23/67 (34%), Gaps = 7/67 (10%) Query: 94 RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEA----TPEMRV 149 +E + AF+LY +G I + I + + +E E V Sbjct: 520 ENVTDEHIREAFQLY---LEGKIAKEAFEEIFKELARNPSKSAREVAEEKGLTLLSEEEV 576 Query: 150 KKIFKLM 156 +I + + Sbjct: 577 TRIIEEV 583 >2KAY-A nrPDB Length = 92 Score = 26.9 bits (58), Expect = 5.4, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Query: 42 QLAREDFVKIYKQFFPFGS-PEDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 L+R++ ++ K+ G E + L DK+++ I F+E+ L+ Sbjct: 28 TLSRKELKELIKKELCLGEMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTML 79 >2YIK-A nrPDB Length = 611 Score = 26.9 bits (58), Expect = 5.5, Method: Composition-based stats. Identities = 9/66 (13%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 101 LSWAFELYDLNHDGY-ITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 L ++ YD N G + + +L+ + + +++ + + ++D + Sbjct: 44 LQYSMFFYDANMCGTGVDENSLLSWRGDCHVYDARLPLDSQNTNMSDGFISSNRSVLDPD 103 Query: 160 EDGYIT 165 DG + Sbjct: 104 GDGKVD 109 >5OLW-A nrPDB Length = 227 Score = 26.5 bits (57), Expect = 6.1, Method: Composition-based stats. Identities = 17/91 (18%), Positives = 37/91 (40%), Gaps = 16/91 (17%) Query: 104 AFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDE---------ATPEMRVKKIFK 154 F+ + DG IT + +K + + +N + + E ++KI Sbjct: 1 MFKAVLFDLDGVIT--DTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILD 58 Query: 155 LMDKNEDGYITLDEFREGSKV-DPSIIGALN 184 L DK ++ +EF+E +K + + + + Sbjct: 59 LADK----KVSAEEFKELAKRKNDNYVKMIQ 85 >5TFQ-A nrPDB Length = 280 Score = 26.5 bits (57), Expect = 6.2, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 36/101 (35%), Gaps = 5/101 (4%) Query: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHL-FTVFDKDNNGFIHF 82 ++I K LA ++ V +Y F F H+ V DK + G I Sbjct: 10 EQQIDSLLKDKKATVGVAVLANDETVAVYNNQIHFPLLSVFKFHVGLAVLDKMDKGHIAL 69 Query: 83 EEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 + I V S+ + L F + D I+ E+L Sbjct: 70 DSLIEVKSSQLKSNTYSPLRDKF----PDQDITISLGELLK 106 >5N1Q-C nrPDB Length = 261 Score = 26.5 bits (57), Expect = 6.3, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 20/52 (38%) Query: 91 TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDE 142 EEKL +Y + +E+LT+V +++ + +E Sbjct: 204 DVGEPLPEEKLREITTIYRKDGVPMRDDEELLTVVKRIHRARTLGGYMPVNE 255 >1Y4C-A nrPDB Length = 494 Score = 26.5 bits (57), Expect = 7.1, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 17/43 (39%) Query: 117 TFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 + +E+L I + + E ++K+ K D+N Sbjct: 387 SSEELLKIALQEAQKTLQQAQELAKKGGGEEQLKRALKRADRN 429 >1Z1W-A nrPDB Length = 780 Score = 26.5 bits (57), Expect = 7.2, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 49/159 (30%), Gaps = 26/159 (16%) Query: 40 SGQLAREDFVKIYKQFFPFGSPE---------DFANHLFTVFDKDNNGFIHFEEFITVLS 90 SG + E + + + FF ++ L FD D F Sbjct: 521 SGHIDPETYRQRIRNFFDDEDHNVITAIVGQMEYLRMLTHAFDDDA------RAFCRSRM 574 Query: 91 TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVK 150 G +E L A G ++ + +V Y S + + D A PEMR Sbjct: 575 QFLTGKQDENLKIAL--------GRVSR--LYVMVDESYAEEMSKLFKDFDSAEPEMRSS 624 Query: 151 KIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGL 189 D L++FR D + ++ + L Sbjct: 625 IATAYALVTGDLKGLLEKFR-SVDRDEDRVRIISAFGKL 662 >1FI6-A nrPDB Length = 92 Score = 26.5 bits (57), Expect = 7.4, Method: Composition-based stats. Identities = 19/60 (31%), Positives = 24/60 (40%), Gaps = 8/60 (13%) Query: 69 FTVFDKDNNGFI---HFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIV 125 F D NGFI +EF T +LS +EL D + DG +T DE Sbjct: 15 FKTIQPDLNGFIPGSAAKEFFT-----KSKLPILELSHIWELSDFDKDGALTLDEFCAAF 69 >4EVF-A nrPDB Length = 295 Score = 26.5 bits (57), Expect = 7.7, Method: Composition-based stats. Identities = 18/42 (42%), Positives = 20/42 (47%), Gaps = 3/42 (7%) Query: 59 GSPEDFANHLFTVFDKDNNGF-IHFEEFITVLSTTSRGTLEE 99 GSPED A L FD+ N + I F F TV S R E Sbjct: 153 GSPEDEAQRLDQAFDQKNTAYLIDF--FGTVPSAEYRPIAEA 192 >5HLO-A nrPDB Length = 94 Score = 26.2 bits (56), Expect = 8.6, Method: Composition-based stats. Identities = 9/21 (42%), Positives = 13/21 (61%) Query: 105 FELYDLNHDGYITFDEMLTIV 125 F+ D+N DG + F E L +V Sbjct: 56 FKELDINTDGAVNFQEFLILV 76 Score = 26.2 bits (56), Expect = 9.2, Method: Composition-based stats. Identities = 8/18 (44%), Positives = 10/18 (55%) Query: 153 FKLMDKNEDGYITLDEFR 170 FK +D N DG + EF Sbjct: 56 FKELDINTDGAVNFQEFL 73 >1J7Q-A nrPDB Length = 86 Score = 26.2 bits (56), Expect = 9.2, Method: Composition-based stats. Identities = 10/74 (13%), Positives = 27/74 (36%), Gaps = 8/74 (10%) Query: 59 GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELY-----DLNHD 113 +D +F +FD++ + + +L+ + + + + D + Sbjct: 10 PEEKDECMKIFDIFDRNAENIAPVSDTMDMLTKLGQTYTKRETEAIMKEARGPKGDKKN- 68 Query: 114 GYITFDEMLTIVAS 127 I +E LT+ + Sbjct: 69 --IGPEEWLTLCSK 80 >2HVQ-A nrPDB Length = 335 Score = 26.2 bits (56), Expect = 9.3, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 23/53 (43%), Gaps = 1/53 (1%) Query: 78 GFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYK 130 G I ++F V+ T + LEE L ++ I E++ +V V + Sbjct: 276 GEIGPKDFGKVMGLTVQDILEETSREGITLTQADNPSLI-KKELVKMVQDVLR 327 >4MN0-A nrPDB Length = 208 Score = 26.2 bits (56), Expect = 9.5, Method: Composition-based stats. Identities = 8/46 (17%), Positives = 17/46 (36%), Gaps = 2/46 (4%) Query: 84 EFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVY 129 E T++ +E FE D + G + E++ + + Sbjct: 149 ELKTMMKAFD--VPQEAAYTFFEKADTDKSGKLERTELVHLFRKFW 192 >2Y5I-A nrPDB Length = 99 Score = 26.2 bits (56), Expect = 9.5, Method: Composition-based stats. Identities = 8/22 (36%), Positives = 13/22 (59%) Query: 149 VKKIFKLMDKNEDGYITLDEFR 170 V+KI +D N+D + +EF Sbjct: 55 VEKIMNDLDSNKDNEVDFNEFV 76 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.135 0.351 Lambda K H 0.267 0.0411 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,329,160 Number of Sequences: 36641 Number of extensions: 285987 Number of successful extensions: 3932 Number of sequences better than 10.0: 366 Number of HSP's better than 10.0 without gapping: 466 Number of HSP's successfully gapped in prelim test: 118 Number of HSP's that attempted gapping in prelim test: 1282 Number of HSP's gapped (non-prelim): 1544 length of query: 190 length of database: 10,336,785 effective HSP length: 92 effective length of query: 98 effective length of database: 6,965,813 effective search space: 682649674 effective search space used: 682649674 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 56 (26.2 bits)