BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q06265 (439 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6H25-A nrPDB 899 0.0 2NN6-A nrPDB 628 e-180 4OO1-A nrPDB 209 2e-54 2PO2-B nrPDB 144 9e-35 2WNR-A nrPDB 143 2e-34 3L7Z-A nrPDB 124 8e-29 6D6R-C nrPDB 120 1e-27 2BA1-H nrPDB 111 7e-25 6D6Q-E nrPDB 102 2e-22 3B4T-A nrPDB 48 7e-06 1E3H-A nrPDB 33 0.17 2PO0-A nrPDB 33 0.24 5K36-E nrPDB 33 0.32 1R6M-A nrPDB 33 0.36 3U1K-A nrPDB 30 1.4 4FIE-A nrPDB 29 5.0 4KKD-A nrPDB 28 6.3 6MS2-A nrPDB 28 6.5 4IW4-E nrPDB 28 8.1 5O9J-A nrPDB 28 9.1 >6H25-A nrPDB Length = 443 Score = 899 bits (2322), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/439 (100%), Positives = 439/439 (100%) Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS Sbjct: 5 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 64 Query: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES Sbjct: 65 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 124 Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER Sbjct: 125 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 184 Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI Sbjct: 185 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 244 Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK Sbjct: 245 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 304 Query: 301 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG Sbjct: 305 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 364 Query: 361 GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQ 420 GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQ Sbjct: 365 GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQ 424 Query: 421 EKAPSKKPVKRRKKKRAAN 439 EKAPSKKPVKRRKKKRAAN Sbjct: 425 EKAPSKKPVKRRKKKRAAN 443 >2NN6-A nrPDB Length = 358 Score = 628 bits (1620), Expect = e-180, Method: Compositional matrix adjust. Identities = 302/302 (100%), Positives = 302/302 (100%) Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS Sbjct: 18 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 77 Query: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES Sbjct: 78 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 137 Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER Sbjct: 138 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 197 Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI Sbjct: 198 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 257 Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK Sbjct: 258 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 317 Query: 301 AP 302 AP Sbjct: 318 AP 319 >4OO1-A nrPDB Length = 305 Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 101/290 (34%), Positives = 173/290 (59%), Gaps = 13/290 (4%) Query: 2 KETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSC 61 K+ +S E +F+L A+ + RLDGR +R++ I+FG ++G V++G T+V ++SC Sbjct: 3 KDIEISASESKFILEALRQNYRLDGRSFDQFRDVEITFGKEFGDVSVKMGNTKVHCRISC 62 Query: 62 ELVSPKLNRATEGILFFNLELSQMAAPAFEPGR-QSDLLVKLNRLMERCLRNSKCIDTES 120 ++ P +R EG+ + E+S MA FE G + V +R++E+ +R S +D E Sbjct: 63 QIAQPYEDRPFEGLFVISTEISPMAGSQFENGNITGEDEVLCSRIIEKSVRRSGALDVEG 122 Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180 LC+VAG K W +R D+H L+ DG IDA+ IA + L HF++PD++V G+++ ++ ER Sbjct: 123 LCIVAGSKCWAVRADVHFLDCDGGFIDASCIAVMAGLMHFKKPDITVHGEQIIVHPVNER 182 Query: 181 DPVPLSIHHMPICVSFAFFQ------------QGTYLLVDPNEREERVMDGLLVIAMNKH 228 +PVPL I H+PICV+F+FF ++D +EE + DG+L + +NK+ Sbjct: 183 EPVPLGILHIPICVTFSFFNPQDTEENIKGETNSEISIIDATLKEELLRDGVLTVTLNKN 242 Query: 229 REICTIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKE 278 RE+ + +GG+ + +++C A + +IT+ IL+ L+ D + R + Sbjct: 243 REVVQVSKAGGLPMDALTLMKCCHEAYSIIEKITDQILQLLKEDSEKRNK 292 >2PO2-B nrPDB Length = 277 Score = 144 bits (362), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 93/268 (34%), Positives = 153/268 (57%), Gaps = 7/268 (2%) Query: 6 LSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGT---DYGCCIVELGKTRVLGQVSCE 62 ++ R ++ ++E KR+D R DYR I I G G +V+LG T+VL + Sbjct: 10 VAGIMRDHIINLLKEGKRIDDRGFEDYRPIEIEVGVIEKAEGSALVKLGSTQVLVGIKTS 69 Query: 63 LVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLC 122 L P + G++ N+EL +A+P FEPG + ++L R+++R +R SK ++ E + Sbjct: 70 LGEPFPDTPNMGVMTTNVELVPLASPTFEPGPPDERAIELARVIDRGIRESKALNLEKMV 129 Query: 123 VVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDP 182 +V G+ V + +D+H+L+HDGN++DA IAAI AL + R P V + + T +E +P Sbjct: 130 IVPGKIVRVVFIDVHVLDHDGNLMDAIGIAAIAALLNARVPKVRYNEETGEVETLDETEP 189 Query: 183 VPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIML 242 +P + +P+ V+FA + G L+VDP+ EE VMDG + I ++ I +Q S G Sbjct: 190 LP--VEKIPVPVTFA--KIGNILVVDPSLDEELVMDGKITITTDETGHISAVQKSEGGAF 245 Query: 243 LKDQVLRCSKIAGVKVAEITELILKALE 270 ++V+ + A K EI +LIL+A+E Sbjct: 246 KLEEVMYAVETAFKKAEEIRKLILEAVE 273 >2WNR-A nrPDB Length = 271 Score = 143 bits (360), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 87/262 (33%), Positives = 150/262 (57%), Gaps = 8/262 (3%) Query: 11 RRFLLRAIEEKKRLDGRQTYDYRNIRISFGT---DYGCCIVELGKTRVLGQVSCELVSPK 67 R+ + I K+R+DGR +++R+I I G G V+LG T+++ V ++ P Sbjct: 13 RKSITDLINNKERIDGRSLHEFRDISIETGVISKAEGSSRVKLGNTQIIVGVKPQIGEPF 72 Query: 68 LNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGE 127 + G++ N EL MA+P FEPG + V+L+R+++RC+R S+ ID E LC++ G Sbjct: 73 PDTPEMGVILTNSELLPMASPTFEPGPPDERSVELSRVVDRCIRESRMIDLEKLCIIEGS 132 Query: 128 KVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSI 187 KVW + +DLH++++DGN+ DAA +A + AL R P V+ EV + E+ P+P++ Sbjct: 133 KVWMLFLDLHIIDYDGNLFDAAVLATVAALLDTRIPAAEVEDGEVVINR-EKMQPLPVNR 191 Query: 188 HHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQV 247 + +C F + G +++DP+ EE ++ + I + + IC +Q G L +D V Sbjct: 192 KAL-MC---TFAKIGNEIVLDPSLEEEDILTARISIGVTEEGSICAMQKGGEGPLTRDDV 247 Query: 248 LRCSKIAGVKVAEITELILKAL 269 L+ IA KV ++ E + K++ Sbjct: 248 LKAVSIAVEKVPQLIEYLDKSM 269 >3L7Z-A nrPDB Length = 271 Score = 124 bits (311), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 80/263 (30%), Positives = 139/263 (52%), Gaps = 24/263 (9%) Query: 9 CERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDY-----GCCIVELGKTRVLGQVSCEL 63 ++ ++ E+ R DGR+ DYR + I+ DY G +V+LG T VL E+ Sbjct: 14 IKKESIVSLFEKGIRQDGRKLTDYRPLSITL--DYAKKADGSALVKLGTTMVLAGTKLEI 71 Query: 64 VSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCV 123 P + +G L N+EL +A FEPG + ++L R+++R LR+SK +D L + Sbjct: 72 DKPYEDTPNQGNLIVNVELLPLAYTTFEPGPPDENAIELARVVDRSLRDSKALDLTKLVI 131 Query: 124 VAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCH---FRRPDVSVQGDEVTLYTPEER 180 G+ VW + +D+++L++ GN++DA ++A++ AL + ++ +SV +EV P Sbjct: 132 EPGKSVWTVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVEQISVNKNEVVGKLP--- 188 Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSG-G 239 +++ + +S A + YL+VDP+ EE +MD + + +I IQ SG G Sbjct: 189 ------LNYPVVTISVAKVDK--YLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKG 240 Query: 240 IMLLK--DQVLRCSKIAGVKVAE 260 M L+ DQ ++ VK+ E Sbjct: 241 SMSLQDIDQAENTARSTAVKLLE 263 >6D6R-C nrPDB Length = 278 Score = 120 bits (301), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 77/258 (29%), Positives = 130/258 (50%), Gaps = 9/258 (3%) Query: 11 RRFLLRAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCELVSPK 67 RRFL +E R DGR+ ++R ++ G T G +V+LG T V+ V E +P Sbjct: 17 RRFL----KENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPS 72 Query: 68 LNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGE 127 + +G + N++L + + F G + ++ + + NS+ I E LC+ G+ Sbjct: 73 TDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGK 132 Query: 128 KVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSI 187 VW + DL L++DGNI+DA + A + AL + + P+V++ +E L + L+I Sbjct: 133 LVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTIN-EETALAEVNLKKKSYLNI 191 Query: 188 HHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQV 247 P+ SFA F T L+VDP EE + G L I M++ ++C + GG L ++ Sbjct: 192 RTHPVATSFAVFDD-TLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKL 250 Query: 248 LRCSKIAGVKVAEITELI 265 C A + E+ +L+ Sbjct: 251 QDCMSRAVTRHKEVKKLM 268 >2BA1-H nrPDB Length = 259 Score = 111 bits (277), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 81/257 (31%), Positives = 133/257 (51%), Gaps = 18/257 (7%) Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRI---SFGTDYGCCIVELGKTRVLG 57 M E L + +R ++L + + +R+DGR ++R + I G +V+LG T+V+ Sbjct: 1 MPEDILVDIKRDYVLSKLRDNERIDGRGFDEFRKVEIIPNVIEKAEGSALVKLGDTQVVV 60 Query: 58 QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 117 V + P + G++ N EL +A+P FEPG + ++L R+++R +R S+ +D Sbjct: 61 GVKMQPGEPYPDTPDRGVIIVNAELVPLASPTFEPGPPDENSIELARVVDRGIRESEAVD 120 Query: 118 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTP 177 L + GEKVW + VD+H L+ DGN++DA+++AAI AL + + P E L Sbjct: 121 LSKLVIEEGEKVWIVFVDIHALDDDGNLLDASALAAIAALMNTKVPAERFDLGEDYL--- 177 Query: 178 EERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSS 237 L + +P+ V+ G LVDP+ E V D L I +K + +Q S Sbjct: 178 -------LPVRDLPVSVTSLIV--GNKYLVDPSREEMSVGDTTLTITTDKDDNVVAMQKS 228 Query: 238 GGIML---LKDQVLRCS 251 GG +L L D++L S Sbjct: 229 GGYLLDEKLFDELLDVS 245 >6D6Q-E nrPDB Length = 293 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 74/240 (30%), Positives = 115/240 (47%), Gaps = 10/240 (4%) Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG 57 M LS E+ +++ ++E R+DGR DYR + + G V+LG T +L Sbjct: 3 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 62 Query: 58 QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 117 V E+ +PKL + EG L F ++ S A P FE DL ++ + R N +D Sbjct: 63 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 122 Query: 118 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGDEVT 173 ++LC+ E W + VD+ LL GN+ DA SIA AL + R P V V +G + Sbjct: 123 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 182 Query: 174 LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERV-MDGLLVIAMNKHREIC 232 + + D + LS+ ++P V+ + G +VD +EE + LLV +K C Sbjct: 183 ELSDDPYDCIRLSVENVPCIVTLC--KIGYRHVVDATLQEEACSLASLLVSVTSKGVVTC 240 >3B4T-A nrPDB Length = 262 Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 53/178 (29%), Positives = 76/178 (42%), Gaps = 32/178 (17%) Query: 21 KKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILF 77 KR DGR ++ R + I+ G G ++E G T+VL S P+ +AT G+ + Sbjct: 5 SKREDGRLDHELRPVIITRGFTENPAGSVLIEFGHTKVLCTASVTEGVPRWRKAT-GLGW 63 Query: 78 FNLELSQMAAPAFE-------PGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVW 130 E + + + GR S +++RL+ R LR CID +L GE Sbjct: 64 LTAEYAMLPSATHSRSDRESVRGRLSGRTQEISRLIGRSLR--ACIDLAAL----GENT- 116 Query: 131 QIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER--DPVPLS 186 I +D +L DG AA A VAL D VT + + DP PLS Sbjct: 117 -IAIDCDVLQADGGTRTAAITGAYVALA-----------DAVTYLSAAGKLSDPRPLS 162 >1E3H-A nrPDB Length = 757 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 3/52 (5%) Query: 16 RAIEEKKRLDGRQTYDYRNIRI---SFGTDYGCCIVELGKTRVLGQVSCELV 64 R I EKKR+DGR D R + + +G + E G+T++LG + ++ Sbjct: 349 RVIAEKKRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNML 400 >2PO0-A nrPDB Length = 249 Score = 33.1 bits (74), Expect = 0.24, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 5/63 (7%) Query: 19 EEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSC--ELVSPKLNRATE 73 E +R+DGR+ Y+ R I++ G G +E GK +++ V EL L R Sbjct: 13 ENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDR 72 Query: 74 GIL 76 IL Sbjct: 73 AIL 75 >5K36-E nrPDB Length = 269 Score = 32.7 bits (73), Expect = 0.32, Method: Compositional matrix adjust. Identities = 56/251 (22%), Positives = 99/251 (39%), Gaps = 45/251 (17%) Query: 6 LSNCERRFLLRAIEEKK--RLDGRQTYDYRNIRIS-------------FGTDYGCCIVEL 50 LS E+ +L ++ R DGR + +R I I +D CIV + Sbjct: 7 LSVAEKSYLYDSLASTPSIRPDGRLPHQFRPIEIFTDFLPSSNGSSRIIASDGSECIVSI 66 Query: 51 GKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLV--KLNRLMER 108 V V EL+ ++ A G++ D LV + L+ + Sbjct: 67 KSKVVDHHVENELLQVDVDIA---------------------GQRDDALVVETITSLLNK 105 Query: 109 CLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQ 168 L++ +D+ L + + ++I VD+ +++ + + S A AL P + Sbjct: 106 VLKSGSGVDSSKLQL-TKKYSFKIFVDVLVISSHSHPVSLISFAIYSALNSTYLPKLISA 164 Query: 169 GDEVT---LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAM 225 D++ L T + D V L I+ P V F G +L+DP E V + L+I+ Sbjct: 165 FDDLEVEELPTFHDYDMVKLDIN--PPLV-FILAVVGNNMLLDPAANESEVANNGLIISW 221 Query: 226 NKHREICTIQS 236 + + I+S Sbjct: 222 SNGKITSPIRS 232 >1R6M-A nrPDB Length = 239 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 40/145 (27%), Positives = 61/145 (42%), Gaps = 19/145 (13%) Query: 23 RLDGRQTYDYRNIRIS-FGTDY--GCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFN 79 R GR R IRI+ T + G +VE G T+V+ VS E P+ + +G + Sbjct: 3 RPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGVPRFLKG-QGQGWLT 61 Query: 80 LELSQMAAPAFE-------PGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQI 132 E + E G+Q +++ RL+ R LR +D L GE + Sbjct: 62 AEYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLR--AALDLSKL----GENT--L 113 Query: 133 RVDLHLLNHDGNIIDAASIAAIVAL 157 +D ++ DG A+ A VAL Sbjct: 114 YIDCDVIQADGGTRTASITGATVAL 138 >3U1K-A nrPDB Length = 630 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 16/174 (9%) Query: 18 IEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLGQVSCE-----LVSPKLN 69 + E KR DGR RN+ F T +G + + G+T+VL V+ + + S ++ Sbjct: 314 LNEYKRCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTVTFDSLESGIKSDQVI 373 Query: 70 RATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKV 129 A GI N L P ++ + K+ L R L + + V+ + Sbjct: 374 TAINGIKDKNFMLHYEFPP-----YATNEIGKVTGLNRRELGHGALAEKALYPVIPRDFP 428 Query: 130 WQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRP-DVSVQGDEVTLYTPEERDP 182 + IRV +L +G+ A++ +AL P +V G + L T + DP Sbjct: 429 FTIRVTSEVLESNGSSSMASACGGSLALMDSGVPISSAVAGVAIGLVT--KTDP 480 >4FIE-A nrPDB Length = 423 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 3/73 (4%) Query: 179 ERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREIC--TIQS 236 E+ P P S P VS F+ L+VDP + +D + I +C T++S Sbjct: 116 EKPPGPRSPQREPQRVSHEQFRAALQLVVDPGD-PRSYLDNFIKIGEGSTGIVCIATVRS 174 Query: 237 SGGIMLLKDQVLR 249 SG ++ +K LR Sbjct: 175 SGKLVAVKKMDLR 187 >4KKD-A nrPDB Length = 433 Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 6/64 (9%) Query: 133 RVDLHLLNHDGNIIDAA--SIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHM 190 V ++L HD A S AA V L PD ++Q + + ++PVPL H M Sbjct: 220 HVTVYLGLHDVRDKSGAVNSSAARVVL----HPDFNIQNYNHDIALVQLQEPVPLGPHVM 275 Query: 191 PICV 194 P+C+ Sbjct: 276 PVCL 279 >6MS2-A nrPDB Length = 538 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 24/53 (45%) Query: 222 VIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQK 274 + N + + C I G + + + C K G K AE L LKA+ N QK Sbjct: 421 YYSTNNYLKCCLIYEEGLKIKVVENRSGCQKTLGKKHAEAGPLFLKAVINKQK 473 >4IW4-E nrPDB Length = 279 Score = 28.1 bits (61), Expect = 8.1, Method: Compositional matrix adjust. Identities = 11/33 (33%), Positives = 19/33 (57%) Query: 162 RPDVSVQGDEVTLYTPEERDPVPLSIHHMPICV 194 PD ++Q + + ++PVPL H MP+C+ Sbjct: 93 HPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCL 125 >5O9J-A nrPDB Length = 184 Score = 27.7 bits (60), Expect = 9.1, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 18/24 (75%) Query: 256 VKVAEITELILKALENDQKVRKEG 279 +KV +I ELI K +EN + +R+EG Sbjct: 19 IKVVKIGELIDKIIENSENIRREG 42 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6H25-A nrPDB 707 0.0 2NN6-A nrPDB 444 e-125 4OO1-A nrPDB 354 7e-98 6D6R-C nrPDB 312 2e-85 2PO2-B nrPDB 300 8e-82 2WNR-A nrPDB 295 2e-80 6D6Q-E nrPDB 282 1e-76 3L7Z-A nrPDB 270 8e-73 2BA1-H nrPDB 267 8e-72 3B4T-A nrPDB 151 4e-37 Sequences not found previously or not previously below threshold: 1R6M-A nrPDB 116 2e-26 1UDQ-A nrPDB 111 5e-25 1OYR-A nrPDB 97 2e-20 3DD6-A nrPDB 96 3e-20 2WNR-B nrPDB 72 7e-13 2BA0-F nrPDB 71 9e-13 2PO0-A nrPDB 71 1e-12 2JEA-B nrPDB 68 8e-12 5K36-E nrPDB 61 8e-10 4OO1-B nrPDB 59 5e-09 3U1K-A nrPDB 58 8e-09 6D6Q-B nrPDB 51 1e-06 3HKM-A nrPDB 45 7e-05 5XEX-A nrPDB 45 9e-05 5YJJ-A nrPDB 43 3e-04 4NBQ-A nrPDB 38 0.008 3H1C-A nrPDB 38 0.010 1E3H-A nrPDB 37 0.016 3CDI-A nrPDB 36 0.037 6D6Q-D nrPDB 35 0.070 4AIM-A nrPDB 35 0.086 6D6K-A nrPDB 34 0.19 5GUP-N nrPDB 32 0.68 5LC5-V nrPDB 31 1.1 5H3C-A nrPDB 31 1.2 5O9J-A nrPDB 30 1.9 5O9I-A nrPDB 30 2.4 4RQF-A nrPDB 30 2.7 6G2J-V nrPDB 30 2.7 6D6Q-F nrPDB 28 8.6 >6H25-A nrPDB Length = 443 Score = 707 bits (1824), Expect = 0.0, Method: Composition-based stats. Identities = 439/439 (100%), Positives = 439/439 (100%) Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS Sbjct: 5 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 64 Query: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES Sbjct: 65 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 124 Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER Sbjct: 125 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 184 Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI Sbjct: 185 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 244 Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK Sbjct: 245 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 304 Query: 301 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG Sbjct: 305 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 364 Query: 361 GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQ 420 GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQ Sbjct: 365 GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQ 424 Query: 421 EKAPSKKPVKRRKKKRAAN 439 EKAPSKKPVKRRKKKRAAN Sbjct: 425 EKAPSKKPVKRRKKKRAAN 443 >2NN6-A nrPDB Length = 358 Score = 444 bits (1142), Expect = e-125, Method: Composition-based stats. Identities = 302/302 (100%), Positives = 302/302 (100%) Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS Sbjct: 18 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 77 Query: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES Sbjct: 78 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 137 Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER Sbjct: 138 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 197 Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI Sbjct: 198 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 257 Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK Sbjct: 258 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 317 Query: 301 AP 302 AP Sbjct: 318 AP 319 >4OO1-A nrPDB Length = 305 Score = 354 bits (907), Expect = 7e-98, Method: Composition-based stats. Identities = 101/290 (34%), Positives = 173/290 (59%), Gaps = 13/290 (4%) Query: 2 KETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSC 61 K+ +S E +F+L A+ + RLDGR +R++ I+FG ++G V++G T+V ++SC Sbjct: 3 KDIEISASESKFILEALRQNYRLDGRSFDQFRDVEITFGKEFGDVSVKMGNTKVHCRISC 62 Query: 62 ELVSPKLNRATEGILFFNLELSQMAAPAFEPGR-QSDLLVKLNRLMERCLRNSKCIDTES 120 ++ P +R EG+ + E+S MA FE G + V +R++E+ +R S +D E Sbjct: 63 QIAQPYEDRPFEGLFVISTEISPMAGSQFENGNITGEDEVLCSRIIEKSVRRSGALDVEG 122 Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180 LC+VAG K W +R D+H L+ DG IDA+ IA + L HF++PD++V G+++ ++ ER Sbjct: 123 LCIVAGSKCWAVRADVHFLDCDGGFIDASCIAVMAGLMHFKKPDITVHGEQIIVHPVNER 182 Query: 181 DPVPLSIHHMPICVSFAFFQ------------QGTYLLVDPNEREERVMDGLLVIAMNKH 228 +PVPL I H+PICV+F+FF ++D +EE + DG+L + +NK+ Sbjct: 183 EPVPLGILHIPICVTFSFFNPQDTEENIKGETNSEISIIDATLKEELLRDGVLTVTLNKN 242 Query: 229 REICTIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKE 278 RE+ + +GG+ + +++C A + +IT+ IL+ L+ D + R + Sbjct: 243 REVVQVSKAGGLPMDALTLMKCCHEAYSIIEKITDQILQLLKEDSEKRNK 292 >6D6R-C nrPDB Length = 278 Score = 312 bits (800), Expect = 2e-85, Method: Composition-based stats. Identities = 74/263 (28%), Positives = 133/263 (50%), Gaps = 5/263 (1%) Query: 12 RFLLRAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCELVSPKL 68 + R ++E R DGR+ ++R ++ G T G +V+LG T V+ V E +P Sbjct: 14 EYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPST 73 Query: 69 NRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEK 128 + +G + N++L + + F G + ++ + + NS+ I E LC+ G+ Sbjct: 74 DAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKL 133 Query: 129 VWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIH 188 VW + DL L++DGNI+DA + A + AL + + P+V++ +E L + L+I Sbjct: 134 VWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTIN-EETALAEVNLKKKSYLNIR 192 Query: 189 HMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVL 248 P+ SFA F T L+VDP EE + G L I M++ ++C + GG L ++ Sbjct: 193 THPVATSFAVFDD-TLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQ 251 Query: 249 RCSKIAGVKVAEITELILKALEN 271 C A + E+ +L+ + +++ Sbjct: 252 DCMSRAVTRHKEVKKLMDEVIKS 274 >2PO2-B nrPDB Length = 277 Score = 300 bits (768), Expect = 8e-82, Method: Composition-based stats. Identities = 93/273 (34%), Positives = 155/273 (56%), Gaps = 7/273 (2%) Query: 5 PLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSC 61 ++ R ++ ++E KR+D R DYR I I G G +V+LG T+VL + Sbjct: 9 IVAGIMRDHIINLLKEGKRIDDRGFEDYRPIEIEVGVIEKAEGSALVKLGSTQVLVGIKT 68 Query: 62 ELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESL 121 L P + G++ N+EL +A+P FEPG + ++L R+++R +R SK ++ E + Sbjct: 69 SLGEPFPDTPNMGVMTTNVELVPLASPTFEPGPPDERAIELARVIDRGIRESKALNLEKM 128 Query: 122 CVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERD 181 +V G+ V + +D+H+L+HDGN++DA IAAI AL + R P V + + T +E + Sbjct: 129 VIVPGKIVRVVFIDVHVLDHDGNLMDAIGIAAIAALLNARVPKVRYNEETGEVETLDETE 188 Query: 182 PVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIM 241 P+P + +P+ V+FA + G L+VDP+ EE VMDG + I ++ I +Q S G Sbjct: 189 PLP--VEKIPVPVTFA--KIGNILVVDPSLDEELVMDGKITITTDETGHISAVQKSEGGA 244 Query: 242 LLKDQVLRCSKIAGVKVAEITELILKALENDQK 274 ++V+ + A K EI +LIL+A+E ++ Sbjct: 245 FKLEEVMYAVETAFKKAEEIRKLILEAVEKAKQ 277 >2WNR-A nrPDB Length = 271 Score = 295 bits (756), Expect = 2e-80, Method: Composition-based stats. Identities = 87/271 (32%), Positives = 150/271 (55%), Gaps = 8/271 (2%) Query: 2 KETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQ 58 K + R+ + I K+R+DGR +++R+I I G G V+LG T+++ Sbjct: 4 KMDIIPEITRKSITDLINNKERIDGRSLHEFRDISIETGVISKAEGSSRVKLGNTQIIVG 63 Query: 59 VSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDT 118 V ++ P + G++ N EL MA+P FEPG + V+L+R+++RC+R S+ ID Sbjct: 64 VKPQIGEPFPDTPEMGVILTNSELLPMASPTFEPGPPDERSVELSRVVDRCIRESRMIDL 123 Query: 119 ESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPE 178 E LC++ G KVW + +DLH++++DGN+ DAA +A + AL R P V+ EV + E Sbjct: 124 EKLCIIEGSKVWMLFLDLHIIDYDGNLFDAAVLATVAALLDTRIPAAEVEDGEVVINR-E 182 Query: 179 ERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSG 238 + P+P++ + F + G +++DP+ EE ++ + I + + IC +Q G Sbjct: 183 KMQPLPVNRKALMC----TFAKIGNEIVLDPSLEEEDILTARISIGVTEEGSICAMQKGG 238 Query: 239 GIMLLKDQVLRCSKIAGVKVAEITELILKAL 269 L +D VL+ IA KV ++ E + K++ Sbjct: 239 EGPLTRDDVLKAVSIAVEKVPQLIEYLDKSM 269 >6D6Q-E nrPDB Length = 293 Score = 282 bits (722), Expect = 1e-76, Method: Composition-based stats. Identities = 78/294 (26%), Positives = 138/294 (46%), Gaps = 14/294 (4%) Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG 57 M LS E+ +++ ++E R+DGR DYR + + G V+LG T +L Sbjct: 3 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 62 Query: 58 QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 117 V E+ +PKL + EG L F ++ S A P FE DL ++ + R N +D Sbjct: 63 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 122 Query: 118 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGDEVT 173 ++LC+ E W + VD+ LL GN+ DA SIA AL + R P V V +G + Sbjct: 123 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 182 Query: 174 LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICT 233 + + D + LS+ ++P V+ + G +VD +EE L++++ + Sbjct: 183 ELSDDPYDCIRLSVENVPCIVTLC--KIGYRHVVDATLQEEACSLASLLVSVTSKGVVTC 240 Query: 234 IQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQK----VRKEGGKFG 283 ++ G L + + + G +V ++ L+++ + ++ R++ G G Sbjct: 241 MRKVGKGSLDPESIFEMME-TGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG 293 >3L7Z-A nrPDB Length = 271 Score = 270 bits (690), Expect = 8e-73, Method: Composition-based stats. Identities = 78/261 (29%), Positives = 136/261 (52%), Gaps = 20/261 (7%) Query: 9 CERRFLLRAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCELVS 65 ++ ++ E+ R DGR+ DYR + I+ G +V+LG T VL E+ Sbjct: 14 IKKESIVSLFEKGIRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDK 73 Query: 66 PKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVA 125 P + +G L N+EL +A FEPG + ++L R+++R LR+SK +D L + Sbjct: 74 PYEDTPNQGNLIVNVELLPLAYTTFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEP 133 Query: 126 GEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHF---RRPDVSVQGDEVTLYTPEERDP 182 G+ VW + +D+++L++ GN++DA ++A++ AL + + +SV +EV Sbjct: 134 GKSVWTVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVEQISVNKNEVVGK------- 186 Query: 183 VPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSG-GIM 241 L +++ + +S A + YL+VDP+ EE +MD + + +I IQ SG G M Sbjct: 187 --LPLNYPVVTISVAKVDK--YLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKGSM 242 Query: 242 LLK--DQVLRCSKIAGVKVAE 260 L+ DQ ++ VK+ E Sbjct: 243 SLQDIDQAENTARSTAVKLLE 263 >2BA1-H nrPDB Length = 259 Score = 267 bits (682), Expect = 8e-72, Method: Composition-based stats. Identities = 84/271 (30%), Positives = 138/271 (50%), Gaps = 18/271 (6%) Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRI---SFGTDYGCCIVELGKTRVLG 57 M E L + +R ++L + + +R+DGR ++R + I G +V+LG T+V+ Sbjct: 1 MPEDILVDIKRDYVLSKLRDNERIDGRGFDEFRKVEIIPNVIEKAEGSALVKLGDTQVVV 60 Query: 58 QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 117 V + P + G++ N EL +A+P FEPG + ++L R+++R +R S+ +D Sbjct: 61 GVKMQPGEPYPDTPDRGVIIVNAELVPLASPTFEPGPPDENSIELARVVDRGIRESEAVD 120 Query: 118 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTP 177 L + GEKVW + VD+H L+ DGN++DA+++AAI AL + + P E L Sbjct: 121 LSKLVIEEGEKVWIVFVDIHALDDDGNLLDASALAAIAALMNTKVPAERFDLGEDYL--- 177 Query: 178 EERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSS 237 L + +P+ V+ G LVDP+ E V D L I +K + +Q S Sbjct: 178 -------LPVRDLPVSVTSLIV--GNKYLVDPSREEMSVGDTTLTITTDKDDNVVAMQKS 228 Query: 238 GGIML---LKDQVLRCSKIAGVKVAEITELI 265 GG +L L D++L S K+ E + I Sbjct: 229 GGYLLDEKLFDELLDVSINCARKLREKFKEI 259 >3B4T-A nrPDB Length = 262 Score = 151 bits (382), Expect = 4e-37, Method: Composition-based stats. Identities = 62/247 (25%), Positives = 96/247 (38%), Gaps = 40/247 (16%) Query: 21 KKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILF 77 KR DGR ++ R + I+ G G ++E G T+VL S P+ +AT G+ + Sbjct: 5 SKREDGRLDHELRPVIITRGFTENPAGSVLIEFGHTKVLCTASVTEGVPRWRKAT-GLGW 63 Query: 78 FNLELSQMAAPAFE-------PGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVW 130 E + + + GR S +++RL+ R LR CID +L GE Sbjct: 64 LTAEYAMLPSATHSRSDRESVRGRLSGRTQEISRLIGRSLR--ACIDLAAL----GENT- 116 Query: 131 QIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER--DPVPLSIH 188 I +D +L DG AA A VAL D VT + + DP PLS Sbjct: 117 -IAIDCDVLQADGGTRTAAITGAYVALA-----------DAVTYLSAAGKLSDPRPLSCA 164 Query: 189 HMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIM----LLK 244 + V + VD E+ + + + + IQ +G Sbjct: 165 IAAVSVGV----VDGRIRVDLPYEEDSRAEVDMNVVATDTGTLVEIQGTGEGATFARSTL 220 Query: 245 DQVLRCS 251 D++L + Sbjct: 221 DKLLDMA 227 >1R6M-A nrPDB Length = 239 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 57/260 (21%), Positives = 96/260 (36%), Gaps = 34/260 (13%) Query: 23 RLDGRQTYDYRNIRISF---GTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFN 79 R GR R IRI+ G +VE G T+V+ VS E P+ + +G + Sbjct: 3 RPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGVPRFLK-GQGQGWLT 61 Query: 80 LELSQMAAPAFE-------PGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQI 132 E + E G+Q +++ RL+ R LR +D L GE + Sbjct: 62 AEYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLR--AALDLSKL----GENT--L 113 Query: 133 RVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPI 192 +D ++ DG A+ A VAL ++V L + M Sbjct: 114 YIDCDVIQADGGTRTASITGATVALID----ALAVLKKRGALKGN--------PLKQMVA 161 Query: 193 CVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQ-SSGGIMLLKDQVLRCS 251 VS +Q ++D + E+ + L + M +Q ++ G ++ Sbjct: 162 AVSVGIYQ--GVPVLDLDYLEDSAAETDLNVVMTDAGGFIEVQGTAEGAPFRPAELNAML 219 Query: 252 KIAGVKVAEITELILKALEN 271 ++A + E+ EL AL Sbjct: 220 ELAQQGMQELFELQRAALAE 239 >1UDQ-A nrPDB Length = 255 Score = 111 bits (278), Expect = 5e-25, Method: Composition-based stats. Identities = 51/257 (19%), Positives = 93/257 (36%), Gaps = 34/257 (13%) Query: 23 RLDGRQTYDYRNIRISF---GTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFN 79 R DGR+ R + I G C++ GKT+V+ S P + +G + Sbjct: 2 RSDGRKEDQLRPVSIQRDFLEYPEGSCLISFGKTKVICTASVIENVPNWLK-GKGQGWIT 60 Query: 80 LELSQMAAPAFEP-------GRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQI 132 E S + + GR ++ R++ R +R ++ + GE+ I Sbjct: 61 AEYSMLPRATQQRTIRESVQGRIGGRTHEIQRMIGRAMR--TAVELTKI----GERT--I 112 Query: 133 RVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPI 192 VD ++ DG AA A VA+ + + + + TP I Sbjct: 113 WVDCDVIQADGGARTAAITGAFVAVADA---IIKLHKEGIIEETP---------IKDFVA 160 Query: 193 CVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSG-GIMLLKDQVLRCS 251 VS +L+D N E+ + + + + + G KD++++ Sbjct: 161 AVSVGIVND--RILLDLNFEEDSAAQVDMNVVGTGSGRLSEVHTMGEEYSFTKDELIKML 218 Query: 252 KIAGVKVAEITELILKA 268 +A + E+ EL K Sbjct: 219 DLAQKGINELIELQKKL 235 >1OYR-A nrPDB Length = 245 Score = 96.7 bits (239), Expect = 2e-20, Method: Composition-based stats. Identities = 47/258 (18%), Positives = 95/258 (36%), Gaps = 33/258 (12%) Query: 23 RLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFN 79 R DGRQ + R I G ++ G T+V+ S E P G + Sbjct: 2 RHDGRQHDELRPITFDLDFISHPEGSVLITAGNTKVICNASVEDRVP-PFLRGGGKGWIT 60 Query: 80 LELSQMAAPAFEP-------GRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQI 132 E S + + G+ S +++ RL+ R LR +D E L GE+ I Sbjct: 61 AEYSMLPRATNQRTIRESSKGKISGRTMEIQRLIGRALR--AVVDLEKL----GERT--I 112 Query: 133 RVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPI 192 +D ++ DG A+ A +A+ + ++ + +P+ + + + Sbjct: 113 WIDCDVIQADGGTRTASITGAFLAMA--------IAIGKLIKAGTIKTNPITDFLAAISV 164 Query: 193 CVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIM-LLKDQVLRCS 251 + + +L+D N E+ + + + M +Q +G ++ + Sbjct: 165 GI-----DKEQGILLDLNYEEDSSAEVDMNVIMTGSGRFVELQGTGEEATFSREDLNGLL 219 Query: 252 KIAGVKVAEITELILKAL 269 +A + E+ + + L Sbjct: 220 GLAEKGIQELIDKQKEVL 237 >3DD6-A nrPDB Length = 255 Score = 96.0 bits (237), Expect = 3e-20, Method: Composition-based stats. Identities = 47/258 (18%), Positives = 98/258 (37%), Gaps = 33/258 (12%) Query: 23 RLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFN 79 R+DGR+ + R+I I G ++E+G T+V+ + E P EG + Sbjct: 12 RVDGREKTELRHIHIHTNYLKHPEGSVLIEVGDTKVICSATIEERVP-PFMRGEGKGWVT 70 Query: 80 LELSQMAAPAFEP-------GRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQI 132 E + + + G+ + +++ RL+ R LR +D E+L GE+ + Sbjct: 71 AEYAMIPRATEQRTIRESSKGKVTGRTMEIQRLIGRALR--AVVDLEAL----GERT--V 122 Query: 133 RVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPI 192 +D ++ DG A+ A VA+ + + + Sbjct: 123 WIDCDVIQADGGTRTASITGAYVAMVLA------------FEKLLQAEKVSKIPVKDYLA 170 Query: 193 CVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIM-LLKDQVLRCS 251 S ++ +++D N E+ D + + M + +Q +G + Q+ Sbjct: 171 ATSVGIVEEQG-VVLDLNYAEDSKADVDMNVIMTGKGQFVEVQGTGEEATFSRAQLNELL 229 Query: 252 KIAGVKVAEITELILKAL 269 A + ++ ++ +AL Sbjct: 230 DAAEQGIFQLIDIQKEAL 247 >2WNR-B nrPDB Length = 240 Score = 71.7 bits (174), Expect = 7e-13, Method: Composition-based stats. Identities = 50/257 (19%), Positives = 92/257 (35%), Gaps = 41/257 (15%) Query: 21 KKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQV--SCELVSPKLNRATEGI 75 R DGR + R ++I G G +E G ++L V E KL R + Sbjct: 15 SVREDGRAFDELRPLKIEAGILERADGSSYLEFGGNKILVAVYGPREAQIRKLQRPDRAV 74 Query: 76 LFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVD 135 + ++ + + V+++++ LR + ++ I V Sbjct: 75 IRCRYNMAPFSVEERKRPGPDRRSVEISKITAEALRPALILEK-----FPRS---VIDVF 126 Query: 136 LHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVS 195 + +L +G A AA VAL P + V+ Sbjct: 127 IEVLEAEGGTRCAGITAASVALADAGIPMRD-------------------------MVVA 161 Query: 196 FAFFQQGTYLLVDPNEREERVMDGLLVIA-MNKHREICTIQSSGGIMLLKDQVLRCSKIA 254 A + G +++D +E E++ + +A + + REI +QS G L ++ R +A Sbjct: 162 CAAGKVGDQVVLDLSEEEDKEGQADVPVAILPRTREITLLQSDGN--LTPEEFERALDLA 219 Query: 255 GVKVAEITELILKALEN 271 I E+ +AL Sbjct: 220 VEGCLRIHEVQKEALRK 236 >2BA0-F nrPDB Length = 258 Score = 70.9 bits (172), Expect = 9e-13, Method: Composition-based stats. Identities = 48/263 (18%), Positives = 97/263 (36%), Gaps = 44/263 (16%) Query: 16 RAIEEKKRLDGRQTYDYRNIRISFGT---DYGCCIVELGKTRVLGQV-SCELVSPK-LNR 70 + I + RLDGR+ + R I+I G C +E+GK +V+ V V P+ L Sbjct: 10 KLIVDGLRLDGRKFDELRPIKIEASVLKRADGSCYLEMGKNKVIAAVFGPREVHPRHLQD 69 Query: 71 ATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVW 130 ++ I+ + ++ + + ++++++ + + + L Sbjct: 70 PSKAIIRYRYNMAPFSVEERKRPGPDRRSIEISKVSKEAFE---AVIMKEL--FPRS--- 121 Query: 131 QIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHM 190 I + + +L D A AA VAL P Sbjct: 122 AIDIFVEVLQADAGSRTACLNAASVALVDAGVPMKG------------------------ 157 Query: 191 PICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAM----NKHREICTIQSSGGIMLLKDQ 246 + S A + L++DP + E+ + + A K I +Q G + +D+ Sbjct: 158 -MITSVAVGKADGQLVLDPMKEEDNFGEADMPFAFLIRNGKIESIALLQMDG--RMTRDE 214 Query: 247 VLRCSKIAGVKVAEITELILKAL 269 V + ++A +I E+ +A+ Sbjct: 215 VKQAIELAKKGALQIYEMQREAI 237 >2PO0-A nrPDB Length = 249 Score = 70.6 bits (171), Expect = 1e-12, Method: Composition-based stats. Identities = 45/258 (17%), Positives = 94/258 (36%), Gaps = 39/258 (15%) Query: 19 EEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQV--SCELVSPKLNRATE 73 E +R+DGR+ Y+ R I++ G G +E GK +++ V EL L R Sbjct: 13 ENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDR 72 Query: 74 GILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIR 133 IL ++ + + ++++++++ L + ++ I Sbjct: 73 AILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEM-----FPRT---AID 124 Query: 134 VDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPIC 193 V + +L D A AA +AL P + + Sbjct: 125 VFIEVLQADAGTRVAGITAASLALADAGIP-----------------------MRDLVAA 161 Query: 194 VSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKI 253 A + +++D N+ E+ + + +A+ + T+ G L KD+ + K+ Sbjct: 162 C--AAGKIEGEIVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGY-LTKDEFIEAVKL 218 Query: 254 AGVKVAEITELILKALEN 271 A + + +AL+ Sbjct: 219 AIKGAKAVYQKQREALKE 236 >2JEA-B nrPDB Length = 250 Score = 67.9 bits (164), Expect = 8e-12, Method: Composition-based stats. Identities = 52/283 (18%), Positives = 104/283 (36%), Gaps = 45/283 (15%) Query: 5 PLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQV-S 60 + ER L+ +++ KR DGR+ + R+I+I G G I E+G T+ + V Sbjct: 5 EMLQVERPKLI--LDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYG 62 Query: 61 CELVSPK-LNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTE 119 + + P+ L+ +L ++ + + S ++L++++ L ++ ++ Sbjct: 63 PKEMHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVEL- 121 Query: 120 SLCVVAGEKVWQIRVDLH--LLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTP 177 +D+ +L D + +AA +AL P Sbjct: 122 ----FPRT-----AIDVFTEILQADAGSRLVSLMAASLALADAGIPMRD----------- 161 Query: 178 EERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSS 237 + A + +++D NE E + + IAM T+ Sbjct: 162 --------------LIAGVAVGKADGVIILDLNETEAMWGEADMPIAMMPSLNQVTLFQL 207 Query: 238 GGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGG 280 G M D+ + +A + I L +AL++ KE G Sbjct: 208 NGSM-TPDEFRQAFDLAVKGINIIYNLEREALKSKYVEFKEEG 249 >5K36-E nrPDB Length = 269 Score = 61.3 bits (147), Expect = 8e-10, Method: Composition-based stats. Identities = 41/242 (16%), Positives = 95/242 (39%), Gaps = 19/242 (7%) Query: 2 KETPLSNCERRFLLRAIEE--KKRLDGRQTYDYRNIRISFG---TDYGCCIVELGK-TRV 55 LS E+ +L ++ R DGR + +R I I + G + + Sbjct: 3 PHMSLSVAEKSYLYDSLASTPSIRPDGRLPHQFRPIEIFTDFLPSSNGSSRIIASDGSEC 62 Query: 56 LGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVK-LNRLMERCLRNSK 114 + + ++V + +L +++++ R L+V+ + L+ + L++ Sbjct: 63 IVSIKSKVVDHHVENE---LLQVDVDIA--------GQRDDALVVETITSLLNKVLKSGS 111 Query: 115 CIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTL 174 +D+ L + + ++I VD+ +++ + + S A AL P + D++ + Sbjct: 112 GVDSSKLQLTK-KYSFKIFVDVLVISSHSHPVSLISFAIYSALNSTYLPKLISAFDDLEV 170 Query: 175 YTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTI 234 + + + F G +L+DP E V + L+I+ + + I Sbjct: 171 EELPTFHDYDMVKLDINPPLVFILAVVGNNMLLDPAANESEVANNGLIISWSNGKITSPI 230 Query: 235 QS 236 +S Sbjct: 231 RS 232 >4OO1-B nrPDB Length = 250 Score = 58.6 bits (140), Expect = 5e-09, Method: Composition-based stats. Identities = 45/266 (16%), Positives = 89/266 (33%), Gaps = 45/266 (16%) Query: 20 EKKRLDGRQTYDYRNIRISFGT----DYGCCIVELGKTRVLGQVSCELVSPKLNRA-TEG 74 E RLDGR+ + R S T G +E G +++ V P+L Sbjct: 14 EGLRLDGRRWNELRRFESSINTHPHAADGSSYMEQGNNKIITLVKG-PKEPRLKSQMDTS 72 Query: 75 ILFFNLELSQMAAPAFEPGRQSD----LLVKLNRLMERCLRNSKCIDTESLCVVAGEKVW 130 N+ ++ FE + S ++++ + R + ++ + Sbjct: 73 KALLNVSVNITKFSKFERSKSSHKNERRVLEIQTSLVRMFEKNVMLN-----IYPRT--- 124 Query: 131 QIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHM 190 I +++H+L DG I+ + +AL D ++ + D PL Sbjct: 125 VIDIEIHVLEQDGGIMGSLINGITLALIDAGISMF----DYISGISVGLYDTTPL----- 175 Query: 191 PICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRC 250 +D N EE M + + + K ++ + I L D++ Sbjct: 176 ----------------LDTNSLEENAMSTVTLGVVGKSEKLSLLLVEDKIPL--DRLENV 217 Query: 251 SKIAGVKVAEITELILKALENDQKVR 276 I + +L+ + L + R Sbjct: 218 LAIGIAGAHRVRDLMDEELRKHAQKR 243 >3U1K-A nrPDB Length = 630 Score = 57.8 bits (138), Expect = 8e-09, Method: Composition-based stats. Identities = 61/287 (21%), Positives = 99/287 (34%), Gaps = 41/287 (14%) Query: 9 CERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG-------- 57 + F + E KR DGR RN+ F T +G + + G+T+VL Sbjct: 305 AKEVFRSIVLNEYKRCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTVTFDSLE 364 Query: 58 -QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCI 116 + + V +N + + E A + LNR R L + Sbjct: 365 SGIKSDQVITAINGIKDKNFMLHYEFPPYATNEI------GKVTGLNR---RELGHGALA 415 Query: 117 DTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYT 176 + V+ + + IRV +L +G+ A++ +AL P +S V + Sbjct: 416 EKALYPVIPRDFPFTIRVTSEVLESNGSSSMASACGGSLALMDSGVP-ISSAVAGVAIGL 474 Query: 177 PEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQ- 235 + DP I LL D E+ D IA I +Q Sbjct: 475 VTKTDPEKGEIED-------------YRLLTDILGIEDYNGDMDFKIAGTNKG-ITALQA 520 Query: 236 --SSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGG 280 GI + V+ + A V EI +++ K + + RKE G Sbjct: 521 DIKLPGIPIKI--VMEAIQQASVAKKEILQIMNKTISKPRASRKENG 565 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 57/320 (17%), Positives = 110/320 (34%), Gaps = 71/320 (22%) Query: 33 RNIRISFGT----DYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAP 88 R + IS G G +V+ G T V+ P ++ + ++ Q AA Sbjct: 15 RKLEISSGKLARFADGSAVVQSGDTAVMVTA-VSKTKPSPSQ----FMPLVVDYRQKAAA 69 Query: 89 A--------FEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLN 140 A SD + +R+++R +R L Sbjct: 70 AGRIPTNYLRREVGTSDKEILTSRIIDRSIRP--------------------------LF 103 Query: 141 HDGNIIDAASIAAIVALCHFRRPDV-SVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFF 199 G D + ++A+ PDV ++ G V L + P+ + I Sbjct: 104 PAGYFYDTQVLCNLLAVDGVNEPDVLAINGASVALSLSDIPWNGPVGAVRIGI------- 156 Query: 200 QQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKVA 259 +V+P +E LV+A +I +++S +L +D K+ Sbjct: 157 -IDGEYVVNPTRKEMSSSTLNLVVAGAPKSQIVMLEASAENILQQD-FCHAIKVGVKYTQ 214 Query: 260 EITELILKALENDQKVRKEGGKF--------GFAESIANQRI----TAFKMEKAPIDTS- 306 +I + I + ++ ++ K + +A +R+ T ++ +K D + Sbjct: 215 QIIQGIQQLVKETGVTKRTPQKLFTPSPEIVKYTHKLAMERLYAVFTDYEHDKVSRDEAV 274 Query: 307 -----DVEEKAEEIIAEAEP 321 D EE+ +E EA+P Sbjct: 275 NKIRLDTEEQLKEKFPEADP 294 >6D6Q-B nrPDB Length = 249 Score = 50.5 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 54/154 (35%), Gaps = 21/154 (13%) Query: 20 EKKRLDGRQTYDYRNIRISFGT---DYGCCIVELGKTRVLG------QVSCELVSPKLNR 70 + R+DGR+ + R I+ G G +E G T+ L ++ +R Sbjct: 14 QGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDR 73 Query: 71 ATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLC-VVAGEKV 129 A N + S + F G + + E L+ + + L + Sbjct: 74 A-----LVNCQYS---SATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRS-- 123 Query: 130 WQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRP 163 QI + + +L DG A AA +A+ P Sbjct: 124 -QIDIYVQVLQADGGTYAACVNAATLAVLDAGIP 156 >3HKM-A nrPDB Length = 246 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 46/249 (18%), Positives = 79/249 (31%), Gaps = 38/249 (15%) Query: 20 EKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQV-SCELVSPKLNRATEGI 75 E+ R DGR R + +G G T VL V + + K + Sbjct: 2 EESRADGRNPNQLRPFSCTRNPLDRAHGSARWAQGDTIVLAAVYGPKPGTRKGENPEKAS 61 Query: 76 LFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVD 135 + + M G+ + ++R L+ S C+ L V I Sbjct: 62 IE--VVWKPMT------GQIGKQEKEYEMTLKRTLQ-SICL----LTVHPNTTTSVI--- 105 Query: 136 LHLLNHDGNIIDAASIAAIVALCHFRRPDVS---------VQGDEVTLYTPEERDPVPLS 186 L ++ +DG+++ A A AL P ++ EV L T + + S Sbjct: 106 LQVVGNDGSLLPCAINACCAALVFAGIPLKHLAVAIGCGVLEDGEVILDTNKAEEQQLKS 165 Query: 187 IHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVI----AMNKHREICTIQSSGGIML 242 H+ S PN++EE GL+ M++ I+ Sbjct: 166 FAHLVFPNSRKSASSKE-----PNQKEEDSERGLITSITHGVMSEEDYFSCIERGLAASS 220 Query: 243 LKDQVLRCS 251 +R + Sbjct: 221 RISDFMRTT 229 >5XEX-A nrPDB Length = 559 Score = 44.7 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 56/321 (17%), Positives = 110/321 (34%), Gaps = 69/321 (21%) Query: 33 RNIRISFGT----DYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAP 88 R++ I G G +V G T VL S S + L N E AA Sbjct: 15 RSLTIETGQLAKQANGAVLVRYGDTVVL---STATASKEPRDGDFFPLTVNYEEKMYAAG 71 Query: 89 AF------EPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHD 142 GR D RL++R +R + +++ +L+ D Sbjct: 72 KIPGGFKKREGRPGDDATLTARLIDRPIRP----------LFPKGYKHDVQIMNMVLSAD 121 Query: 143 GNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQG 202 PD S Q + + LS+ +P A G Sbjct: 122 --------------------PDCSPQMAAMIGSSMA------LSVSDIPFQGPIAGVNVG 155 Query: 203 TY---LLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKVA 259 +++P E+ V L + + H++ + +G + + ++L ++ Sbjct: 156 YIDGKYIINPTVEEKEV--SRLDLEVAGHKDAVNMVEAGASEITEQEMLEAIFFGHEEIQ 213 Query: 260 EITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKA---PIDTSDVEEKAE--- 313 + + + +++ Q V++E E++ +R+ + EK + T D +++ E Sbjct: 214 RLVDFQQQIVDHIQPVKQEFIPAERDEALV-ERVKSLTEEKGLKETVLTFDKQQRDENLD 272 Query: 314 --------EIIAEAEPPSEVV 326 E I E +P +E++ Sbjct: 273 NLKEEIVNEFIDEEDPENELL 293 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 40/271 (14%), Positives = 83/271 (30%), Gaps = 27/271 (9%) Query: 5 PLSNCERRFLLRAI-EEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVS 60 L+ + + R I +EK R DGR+ + R + G +G + G+T+ L ++ Sbjct: 300 ILNELVKEEVRRLIADEKIRPDGRKPDEIRPLDSEVGILPRTHGSGLFTRGQTQALSVLT 359 Query: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120 + G + P F G + R + + + Sbjct: 360 LGALGDYQLIDGLGPEEEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERA--LKY 417 Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180 + + + IR+ +L +G+ A+ + +AL P Sbjct: 418 IIPDTADFPYTIRIVSEVLESNGSSSQASICGSTLALMDAGVP---------IKAPVAG- 467 Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240 I + + +L D E+ + D +A K Sbjct: 468 -----------IAMGLVTREDSYTILTDIQGMEDALGDMDFKVAGTKEGITAIQMDIKID 516 Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALEN 271 L ++ + + A EI +L+ ++ Sbjct: 517 GLTREIIEEALEQARRGRLEIMNHMLQTIDQ 547 >5YJJ-A nrPDB Length = 713 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 40/274 (14%), Positives = 83/274 (30%), Gaps = 27/274 (9%) Query: 5 PLSNCERRFLLRAI-EEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVS 60 L++ + + R I +EK R DGR+ + R + G +G + G+T+ L ++ Sbjct: 312 ILNDLIKEEVRRLIADEKIRPDGRKVDEIRPLESEVGLLPRAHGSGLFTRGQTQALSVLT 371 Query: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120 + G + P F G + R + + Sbjct: 372 LGALGDYQLIDGLGPEVEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERA--LRY 429 Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180 + + + IR+ +L +G+ A+ + +AL P Sbjct: 430 IIPDTQDFPYTIRIVSEVLESNGSSSQASICGSTLALMDAGVP---------IKAPVAG- 479 Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240 I + +L D E+ + D +A K Sbjct: 480 -----------IAMGLVTRDDSYTILTDIQGMEDALGDMDFKVAGTKDGITAIQMDIKID 528 Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQK 274 L ++ + + A I + +L +E ++ Sbjct: 529 GLTREVIEEALEQARQGRLAIMDHMLHTIEQPRE 562 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 40/259 (15%), Positives = 85/259 (32%), Gaps = 54/259 (20%) Query: 33 RNIRISFGT----DYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAP 88 R++ I G G +V G T VL S S + L N E AA Sbjct: 27 RSLTIETGQLAKQANGAVLVRYGDTVVL---STATASKEPRDGDFFPLTVNYEEKMYAAG 83 Query: 89 AF------EPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHD 142 GR D RL++R +R + +++ +L+ D Sbjct: 84 KIPGGFKKREGRPGDEATLTARLIDRPIRP----------LFPKGYRHDVQIMNIVLSAD 133 Query: 143 GNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQG 202 PD S + + + LS+ +P A G Sbjct: 134 --------------------PDCSPEMAAMIGSSMA------LSVSDIPFQGPIAGVNVG 167 Query: 203 TY---LLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKVA 259 +++P+ ++ + L + + H++ + +G + + ++L ++ Sbjct: 168 YIDGKYVINPSVADKEI--SRLDLEVAGHKDAVNMVEAGASEITESEMLEAIFFGHEEIK 225 Query: 260 EITELILKALENDQKVRKE 278 + + +++ Q +++E Sbjct: 226 RLVAFQQEIIDHIQPIKQE 244 >4NBQ-A nrPDB Length = 715 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 46/281 (16%), Positives = 84/281 (29%), Gaps = 45/281 (16%) Query: 4 TPLSNCERRFLLRAIEEKK-RLDGRQTYDYRNIRISFGT---DYGCCIVELGKTRVLGQV 59 ERR + I + R+DGR T R I + G +G + G+T+ L V Sbjct: 317 VIFHELERRIVREQILTGQPRIDGRDTKTVRPITVKVGVLPRSHGSALFTRGETQAL--V 374 Query: 60 SCELVSPK-------LNRATEGILFFNLELSQMAAPA--FEPGRQSDLLVKLNRLMERCL 110 L + + L+ + F+ F G + RL +R + Sbjct: 375 VTTLGTERDAQSIDDLDGDRQEEFIFHYNFPPFCVGEVGFMSG-PKRREIGHGRLAKRAV 433 Query: 111 RNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGD 170 + + + IRV +L +G+ A+ + +AL P Sbjct: 434 --------VPVVPTLDKFPYVIRVVSEILESNGSSSMASVCGSSLALMDAGVP------- 478 Query: 171 EVTLYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHRE 230 T I + +L D E+ + D +A + Sbjct: 479 --TKAPVAG------------IAMGLIKENDKYAVLSDILGDEDHLGDMDFKVAGTSNGV 524 Query: 231 ICTIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALEN 271 + K+ + + A I ++ K L+ Sbjct: 525 TALQMDIKIEGITKEIMEQALDQAKEGRLHILSIMNKVLDK 565 Score = 32.4 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 37/95 (38%), Gaps = 10/95 (10%) Query: 27 RQTYDYRNIRISFGT------DYGCCIVELGKTRVLGQV--SCELVSPKLNRA-TEGILF 77 R+T+ Y ++F T G +V +G T +L V E + T Sbjct: 24 RKTFQYGKHEVTFETGEMARQATGAVVVRMGDTVLLVSVVAKKEAEEGRDFFPLTVNYQE 83 Query: 78 FNLELSQMAAPAFEP-GRQSDLLVKLNRLMERCLR 111 ++ F+ GR ++ +RL++R LR Sbjct: 84 KTYAAGKIPGGYFKREGRPTEKETLTSRLIDRPLR 118 >3H1C-A nrPDB Length = 549 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 47/310 (15%), Positives = 100/310 (32%), Gaps = 59/310 (19%) Query: 34 NIRISFG----TDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQ----- 84 + + G +V + T V V + K + + + + Sbjct: 15 TVTLETGMMARQATAAVMVSMDDTAVFVTVVGQ----KKAKPGQDFFPLTVNYQERTYAA 70 Query: 85 --MAAPAFEP-GRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNH 141 + F GR S+ + RL++R +R L Sbjct: 71 GRIPGSFFRREGRPSEGETLIARLIDRPIRP--------------------------LFP 104 Query: 142 DGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQ 201 +G + + IA +V++ P V+ + + LS+ +P + Sbjct: 105 EGFVNEVQVIATVVSV----NPQVNPDIVAMIGASAA------LSLSGIPFNGPIGAARV 154 Query: 202 GTY---LLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKV 258 G +++P + E + + L + + + S +L +DQ+L + Sbjct: 155 GYINDQYVLNPTQDE--LKESKLDLVVAGTEAAVLMVESEAQLLSEDQMLGAVVFGHEQQ 212 Query: 259 AEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAE 318 + + I + ++ K R + E++ N R+ A E D + +K E Sbjct: 213 QVVIQNINELVKEAGKPRWDWQPEPVNEAL-NARVAALA-EARLSDAYRITDKQERYAQV 270 Query: 319 AEPPSEVVST 328 SE ++T Sbjct: 271 DVIKSETIAT 280 Score = 36.3 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 42/261 (16%), Positives = 81/261 (31%), Gaps = 67/261 (25%) Query: 3 ETPLSNCERRFLLRAIEEKK----------RLDGRQTYDYRNIRISFGT---DYGCCIVE 49 + L E +L AIE+ R+DGR+ R + + G +G + Sbjct: 285 DETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFT 344 Query: 50 LGKTRVLGQVSC----------ELVSPKLNRATEGILFFNLELSQ-MAAPAFEPGRQSDL 98 G+T+ L + EL+ + + F+ G Sbjct: 345 RGETQALVTATLGTARDAQVLDELMGERTDT-----FLFHYNFPPYSVGETGMVGSPKRR 399 Query: 99 LVKLNRLMERCLRNSKCIDTESLCVVA--GEKVWQIRVDLHLLNHDGNIIDAASIAAIVA 156 + RL +R + L V+ + + +RV + +G+ A+ A +A Sbjct: 400 EIGHGRLAKRGV----------LAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLA 449 Query: 157 LCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLV--DPNEREE 214 L P I ++ ++G +V D E+ Sbjct: 450 LMDAGVP-----------------------IKAAVAGIAMGLVKEGDNYVVLSDILGDED 486 Query: 215 RVMDGLLVIAMNKHREICTIQ 235 + D +A ++ I +Q Sbjct: 487 HLGDMDFKVAGSRDG-ISALQ 506 >1E3H-A nrPDB Length = 757 Score = 37.0 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 30/70 (42%), Gaps = 8/70 (11%) Query: 2 KETPLSNCERRFLLRAIEE-----KKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKT 53 +E +S R + E KKR+DGR D R + +G + E G+T Sbjct: 330 REKEISAAYRALTKSLVRERVIAEKKRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGET 389 Query: 54 RVLGQVSCEL 63 ++LG + + Sbjct: 390 QILGVTTLNM 399 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 34/91 (37%), Gaps = 11/91 (12%) Query: 33 RNIRISFGT----DYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQ---- 84 R IR G G + L ++ + +PK ++ L ++E Sbjct: 37 RTIRFETGRLARQAAGSAVAYLDDDTMVLSATTASKNPK-DQLDFFPLTVDVEERMYAAG 95 Query: 85 -MAAPAFEP-GRQSDLLVKLNRLMERCLRNS 113 + F GR S+ + RL++R LR S Sbjct: 96 KIPGSFFRREGRPSEDAILTCRLIDRPLRPS 126 >3CDI-A nrPDB Length = 723 Score = 35.9 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 46/298 (15%), Positives = 97/298 (32%), Gaps = 55/298 (18%) Query: 42 DYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQ-------MAAPAFEP-G 93 +V + T V V + K + + + + + F G Sbjct: 33 ATAAVMVSMDDTAVFVTVVGQ----KKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREG 88 Query: 94 RQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAA 153 R S+ + RL++R +R L +G + + IA Sbjct: 89 RPSEGETLIARLIDRPIRP--------------------------LFPEGFVNEVQVIAT 122 Query: 154 IVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQGTY---LLVDPN 210 +V++ P V+ + + LS+ +P + G +++P Sbjct: 123 VVSV----NPQVNPDIVAMIGASAA------LSLSGIPFNGPIGAARVGYINDQYVLNPT 172 Query: 211 EREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALE 270 + E + + L + + + S +L +DQ+L + + + I + ++ Sbjct: 173 QDE--LKESKLDLVVAGTEAAVLMVESEAQLLSEDQMLGAVVFGHEQQQVVIQNINELVK 230 Query: 271 NDQKVRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVST 328 K R + E++ N R+ A E D + +K E SE ++T Sbjct: 231 EAGKPRWDWQPEPVNEAL-NARVAALA-EARLSDAYRITDKQERYAQVDVIKSETIAT 286 Score = 34.7 bits (78), Expect = 0.084, Method: Composition-based stats. Identities = 42/261 (16%), Positives = 81/261 (31%), Gaps = 67/261 (25%) Query: 3 ETPLSNCERRFLLRAIEEKK----------RLDGRQTYDYRNIRISFGT---DYGCCIVE 49 + L E +L AIE+ R+DGR+ R + + G +G + Sbjct: 291 DETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFT 350 Query: 50 LGKTRVLGQVSC----------ELVSPKLNRATEGILFFNLELSQ-MAAPAFEPGRQSDL 98 G+T+ L + EL+ + + F+ G Sbjct: 351 RGETQALVTATLGTARDAQVLDELMGERTDT-----FLFHYNFPPYSVGETGMVGSPKRR 405 Query: 99 LVKLNRLMERCLRNSKCIDTESLCVVA--GEKVWQIRVDLHLLNHDGNIIDAASIAAIVA 156 + RL +R + L V+ + + +RV + +G+ A+ A +A Sbjct: 406 EIGHGRLAKRGV----------LAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLA 455 Query: 157 LCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLV--DPNEREE 214 L P I ++ ++G +V D E+ Sbjct: 456 LMDAGVP-----------------------IKAAVAGIAMGLVKEGDNYVVLSDILGDED 492 Query: 215 RVMDGLLVIAMNKHREICTIQ 235 + D +A ++ I +Q Sbjct: 493 HLGDMDFKVAGSRDG-ISALQ 512 >6D6Q-D nrPDB Length = 237 Score = 35.1 bits (79), Expect = 0.070, Method: Composition-based stats. Identities = 36/224 (16%), Positives = 72/224 (32%), Gaps = 41/224 (18%) Query: 23 RLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLEL 82 R G + + G G T VL V E + + E+ Sbjct: 24 RGPGCSLRHFACEQNLLSRPDGSASFLQGDTSVLAGVY---------GPAE--VKVSKEI 72 Query: 83 SQMAAPAFEPGRQSDLLVKLNRLMERCLRNS-KCIDTESLCVVAGEKVWQIRVDLHLLNH 141 A + L + ER +RN+ + + +L + + L +++ Sbjct: 73 FNKATLEVILRPKIGLPGVAEKSRERLIRNTCEAVVLGTL--HPRTSITVV---LQVVSD 127 Query: 142 DGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQ 201 G+++ AA +AL P + + V+ A Sbjct: 128 AGSLLACCLNAACMALVDAGVP-----------------------MRALFCGVACALDSD 164 Query: 202 GTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKD 245 GT L++DP ++E+ +L A++ + S+ G+ + Sbjct: 165 GT-LVLDPTSKQEKEARAVLTFALDSVERKLLMSSTKGLYSDTE 207 >4AIM-A nrPDB Length = 726 Score = 34.7 bits (78), Expect = 0.086, Method: Composition-based stats. Identities = 40/273 (14%), Positives = 77/273 (28%), Gaps = 41/273 (15%) Query: 7 SNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCEL 63 ++ RR +L R+DGR R I G +G + G+T+ + + Sbjct: 318 ADVVRRGILDT---GLRIDGRDVKTVRPILGEVGILPRTHGSALFTRGETQAIVVATLGT 374 Query: 64 V--SPKLNRATEGI---LFFNLELSQ-MAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 117 ++ + G + +L R LR Sbjct: 375 GDDEQFIDALEGTYKESFLLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRALR------ 428 Query: 118 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTP 177 + + + IR+ + +G+ A + +A+ P V Sbjct: 429 --PMLPTKEDFPYTIRLVSEITESNGSSSMATVCGSSLAMMDAGVPLVR----------- 475 Query: 178 EERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSS 237 P+S I + Q G +L D E+ + D +A Sbjct: 476 ------PVS----GIAMGLILEQDGFAVLSDILGDEDHLGDMDFKVAGTSEGLTSLQMDI 525 Query: 238 GGIMLLKDQVLRCSKIAGVKVAEITELILKALE 270 + + + A A I + KA++ Sbjct: 526 KIAGITPAIMEQALAQAKEGRAHILGEMNKAMD 558 Score = 33.2 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 47/282 (16%), Positives = 98/282 (34%), Gaps = 61/282 (21%) Query: 3 ETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCE 62 ++P+ + +R+ + + GR G + +G+T VL Sbjct: 12 QSPMFDIKRKTIEWGGKTLVLETGRIARQ----------ADGAVLATMGETVVLATA--- 58 Query: 63 LVSPKLNRATEGILFFNLELSQ-------MAAPAFEP-GRQSDLLVKLNRLMERCLRNSK 114 V K + + + + + F+ GR S+ ++RL++R +R Sbjct: 59 -VFAKSQKPGQDFFPLTVNYQEKTFAAGKIPGGFFKREGRPSEKETLVSRLIDRPIR--- 114 Query: 115 CIDTESLCVVAGEKVWQIRVDL--HLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEV 172 L V + Q+ V + H L +D +I+ +AA ALC P + Sbjct: 115 -----PLFVKGFKNEVQVVVTVLQHDLENDPDIL--GMVAASAALCLSGAPFMG------ 161 Query: 173 TLYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREIC 232 PI + + G Y +++P E + + + + + + Sbjct: 162 ------------------PIGAARVGWVDGAY-VLNPTLDEMK--ESKMDLVVAGTADAV 200 Query: 233 TIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQK 274 + S L ++ VL A ++ + + I+ E+ K Sbjct: 201 MMVESEIQELSEEIVLGGVNFAHQQMQAVIDAIIDLAEHAAK 242 >6D6K-A nrPDB Length = 705 Score = 33.6 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 35/232 (15%), Positives = 74/232 (31%), Gaps = 38/232 (16%) Query: 11 RRFLLRAIEEKKRLDGRQTYDYRNIRISFGT---DYGCCIVELGKTRVLGQVSCELVSPK 67 R +L K R+DGR T R + + G +G + G+T+ L L + + Sbjct: 316 RDNILSG---KPRIDGRDTKTVRALDVQVGVLERAHGSALFTRGETQALVTT--TLGNTR 370 Query: 68 LNRATEGILFFNLELSQMAA--PAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVA 125 + + + + PA+ G R + + + ++ A Sbjct: 371 DALMVDTLAGTKTDNFMLHYNFPAYSVGETGRESGPKRREIGHGRLARRGVQ--AVLPAA 428 Query: 126 GEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPL 185 + IR+ + +G+ A+ A ++L P Sbjct: 429 DRFPYVIRIVSDITESNGSSSMASVCGASLSLMDAGVP---------------------- 466 Query: 186 SIHHMPICVSFAFFQQGTYLLV--DPNEREERVMDGLLVIAMNKHREICTIQ 235 + ++ ++G V D E+ + D +A + + I +Q Sbjct: 467 -LKAPVAGIAMGLVKEGERFAVLSDILGDEDHLGDMDFKVAGSANG-ITALQ 516 >5GUP-N nrPDB Length = 116 Score = 31.6 bits (70), Expect = 0.68, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 43/113 (38%), Gaps = 8/113 (7%) Query: 240 IMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKME 299 +L K L + + L K L+ ++ K + E I N+++ M Sbjct: 3 GLLKKTTGLVGLAVCETPHERLKILYTKILDVLGQIPKNAAYRKYTEQITNEKL---GMV 59 Query: 300 KAPIDTSDVEEK-----AEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSW 347 KA D +EE+ EE+I +AE + + W P + E N W Sbjct: 60 KAEPDVKKLEEQLQGGQIEEVILQAENELSLARKMLRWKPWEPLVEEPPANQW 112 >5LC5-V nrPDB Length = 116 Score = 30.9 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 25/113 (22%), Positives = 43/113 (38%), Gaps = 8/113 (7%) Query: 240 IMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKME 299 +L K L + + L K L+ + K + E I N++++ M Sbjct: 3 GLLKKTTGLVGLAVCETPHERLKILYTKILDVLGHIPKNAAYRKYTEQITNEKLS---MV 59 Query: 300 KAPIDTSDVEEK-----AEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSW 347 KA D +EE+ EE+I +AE + + W P + E + W Sbjct: 60 KAEPDVKKLEERLQGGQIEEVILQAENELSLARKMIQWKPWEPLVEEPPASQW 112 >5H3C-A nrPDB Length = 174 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Query: 252 KIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITA-FKMEKAPIDTSDVEE 310 + +V + T K E K + E K + +++A + A + + K P + + +EE Sbjct: 98 HVDASEVKKQTGEFGKVFEETCKAKSEDEKQSWKQALAAVAVMAGYDLRKWPSEAAMIEE 157 Query: 311 KAEEIIAEAEPPSE 324 AE+++ + PS+ Sbjct: 158 LAEDVLRKTMTPSD 171 >5O9J-A nrPDB Length = 184 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 25/42 (59%) Query: 238 GGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEG 279 GG + ++ + + +KV +I ELI K +EN + +R+EG Sbjct: 1 GGYAVDYNEPIIIKENGEIKVVKIGELIDKIIENSENIRREG 42 >5O9I-A nrPDB Length = 195 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 25/43 (58%) Query: 237 SGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEG 279 SGG + + + + +KV +I ELI + ++N + VRK+G Sbjct: 1 SGGYAVDYSEPIIIKEKGEIKVVKIGELIDEIIKNSKNVRKDG 43 >4RQF-A nrPDB Length = 522 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 8/101 (7%) Query: 285 AESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTA-----QI 339 A+++AN +++ K + ID + ++ AE I EAE + L P + Sbjct: 92 ADALANLKVSQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDV 151 Query: 340 GEGVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVS 380 VE WGD +K D +++DG + + G V+ Sbjct: 152 DNKVERIWGDCTVRKKYSHV---DLVVMVDGFEGEKGAVVA 189 >6G2J-V nrPDB Length = 116 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 39/112 (34%), Gaps = 14/112 (12%) Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300 L+ V + T ILK RK + E I N+++ M K Sbjct: 10 GLVGLAVCDTPHERLTILYTKTLDILKHFPKHAAYRK------YTEQITNEKL---DMVK 60 Query: 301 APIDTSDVEE-----KAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSW 347 A D +E + EE+I +AE + + W P + E N W Sbjct: 61 AEPDVKKLEALLQGGEVEEVILQAEKELSLARKMLKWKPWEPLVEEPPANQW 112 >6D6Q-F nrPDB Length = 272 Score = 27.8 bits (60), Expect = 8.6, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 20/49 (40%), Gaps = 3/49 (6%) Query: 15 LRAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVS 60 L A +E++ R R + G G +E G T+VL VS Sbjct: 19 LYAADEEEAPGTRDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVS 67 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.127 0.320 Lambda K H 0.267 0.0396 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,219,190 Number of Sequences: 36641 Number of extensions: 591580 Number of successful extensions: 1833 Number of sequences better than 10.0: 44 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 41 Number of HSP's that attempted gapping in prelim test: 1718 Number of HSP's gapped (non-prelim): 100 length of query: 439 length of database: 10,336,785 effective HSP length: 100 effective length of query: 339 effective length of database: 6,672,685 effective search space: 2262040215 effective search space used: 2262040215 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.8 bits)