BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q06124 (593 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4H1O-A nrPDB 1126 0.0 6CMQ-A nrPDB 865 0.0 3PS5-A nrPDB 664 0.0 2B3O-A nrPDB 658 0.0 4PVG-A nrPDB 614 e-176 4HJQ-A nrPDB 365 e-101 2OOQ-A nrPDB 213 2e-55 2C7S-A nrPDB 213 2e-55 1YFO-A nrPDB 213 2e-55 1RPM-A nrPDB 206 3e-53 6D4D-A nrPDB 204 1e-52 2JJD-A nrPDB 204 1e-52 4BPC-A nrPDB 202 4e-52 2NLK-A nrPDB 199 4e-51 2PBN-A nrPDB 197 1e-50 1LAR-A nrPDB 194 8e-50 1WCH-A nrPDB 191 6e-49 5AWX-A nrPDB 191 7e-49 2NV5-A nrPDB 189 2e-48 4BJO-A nrPDB 189 2e-48 1L8K-A nrPDB 189 3e-48 3I36-A nrPDB 187 1e-47 5HDE-A nrPDB 184 1e-46 2H03-A nrPDB 182 3e-46 6H8S-A nrPDB 181 1e-45 1P15-A nrPDB 180 1e-45 2CFV-A nrPDB 179 4e-45 3OLR-A nrPDB 178 5e-45 3S3F-A nrPDB 176 2e-44 2PI7-A nrPDB 176 2e-44 5OVR-A nrPDB 176 3e-44 2I75-A nrPDB 175 6e-44 2A8B-A nrPDB 174 1e-43 2GJT-A nrPDB 173 2e-43 4GFV-A nrPDB 172 4e-43 1YGU-A nrPDB 171 7e-43 2QEP-A nrPDB 171 7e-43 2I1Y-A nrPDB 168 5e-42 1ZC0-A nrPDB 167 1e-41 4GE6-A nrPDB 165 7e-41 4IKC-A nrPDB 161 9e-40 6D3F-A nrPDB 161 9e-40 2BZL-A nrPDB 160 2e-39 4RHG-A nrPDB 160 2e-39 4AZ1-A nrPDB 107 2e-23 3M4U-A nrPDB 100 1e-21 2PLE-A nrPDB 63 5e-10 4XEY-B nrPDB 58 9e-09 2FO0-A nrPDB 58 1e-08 2AUG-A nrPDB 57 2e-08 2ABL-A nrPDB 57 2e-08 6AMW-A nrPDB 57 3e-08 1A81-A nrPDB 57 3e-08 4FL3-A nrPDB 57 3e-08 3T04-A nrPDB 56 3e-08 1GRI-A nrPDB 56 4e-08 1K9A-A nrPDB 53 5e-07 2LQW-A nrPDB 52 5e-07 6F3F-A nrPDB 52 1e-06 2H8H-A nrPDB 51 2e-06 2EOB-A nrPDB 50 2e-06 5U06-A nrPDB 50 3e-06 1MIL-A nrPDB 50 3e-06 2EYZ-A nrPDB 49 5e-06 2KK6-A nrPDB 49 6e-06 1AD5-A nrPDB 49 7e-06 2EKX-A nrPDB 49 8e-06 2LCT-A nrPDB 48 1e-05 2CRH-A nrPDB 48 2e-05 4XI2-A nrPDB 47 2e-05 2HDV-A nrPDB 47 3e-05 1NRV-A nrPDB 46 4e-05 2OZO-A nrPDB 45 1e-04 3CXL-A nrPDB 44 1e-04 1XA6-A nrPDB 44 1e-04 4XZ1-A nrPDB 44 2e-04 4M4Z-A nrPDB 43 3e-04 2CS0-A nrPDB 43 3e-04 1M27-A nrPDB 42 7e-04 1KA6-A nrPDB 42 0.001 3RO1-A nrPDB 42 0.001 1RPY-A nrPDB 41 0.001 6DR7-A nrPDB 40 0.002 1G4W-R nrPDB 39 0.006 5M6U-B nrPDB 39 0.009 3QWY-A nrPDB 38 0.010 4E93-A nrPDB 38 0.011 4GL9-E nrPDB 38 0.013 2HMH-A nrPDB 38 0.014 2BBU-A nrPDB 37 0.018 5Z59-A nrPDB 37 0.035 1OHC-A nrPDB 36 0.044 5LXQ-B nrPDB 36 0.044 6C7Y-B nrPDB 36 0.058 5K23-A nrPDB 36 0.060 1ZCK-A nrPDB 35 0.065 3RZ2-A nrPDB 35 0.086 1V3A-A nrPDB 34 0.18 5K22-A nrPDB 34 0.20 5IXI-A nrPDB 33 0.27 3F41-A nrPDB 33 0.34 6C5X-D nrPDB 33 0.41 4ERC-A nrPDB 33 0.42 2OZ5-A nrPDB 32 0.74 5XW4-A nrPDB 32 0.80 4NX8-A nrPDB 32 0.97 1G85-A nrPDB 31 1.4 5BO8-A nrPDB 31 1.8 2M3V-A nrPDB 31 1.8 5BO9-A nrPDB 30 2.0 4R0S-A nrPDB 30 2.8 5UJY-A nrPDB 30 3.8 4JGH-A nrPDB 29 5.0 4MIF-A nrPDB 29 6.4 4PKA-X nrPDB 29 6.9 5BPD-A nrPDB 28 8.9 4IFQ-A nrPDB 28 9.0 4ZO7-A nrPDB 28 9.1 >4H1O-A nrPDB Length = 560 Score = 1126 bits (2912), Expect = 0.0, Method: Compositional matrix adjust. Identities = 538/539 (99%), Positives = 538/539 (99%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG Sbjct: 22 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 81 Query: 61 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 120 YYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK Sbjct: 82 GYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 141 Query: 121 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 180 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD Sbjct: 142 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 201 Query: 181 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 240 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT Sbjct: 202 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 261 Query: 241 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 300 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP Sbjct: 262 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 321 Query: 301 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 360 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV Sbjct: 322 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 381 Query: 361 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF 420 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF Sbjct: 382 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF 441 Query: 421 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 480 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR Sbjct: 442 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 501 Query: 481 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG 539 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG Sbjct: 502 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG 560 >6CMQ-A nrPDB Length = 427 Score = 865 bits (2234), Expect = 0.0, Method: Compositional matrix adjust. Identities = 424/425 (99%), Positives = 424/425 (99%) Query: 105 ADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164 DPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK Sbjct: 3 GDPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 62 Query: 165 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAA 224 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAA Sbjct: 63 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAA 122 Query: 225 EIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILP 284 EIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILP Sbjct: 123 EIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILP 182 Query: 285 FDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRM 344 FDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRM Sbjct: 183 FDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRM 242 Query: 345 VFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLS 404 VFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLS Sbjct: 243 VFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLS 302 Query: 405 KVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIG 464 KVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIG Sbjct: 303 KVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIG 362 Query: 465 RTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIET 524 RTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIET Sbjct: 363 RTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIET 422 Query: 525 LQRRI 529 LQRRI Sbjct: 423 LQRRI 427 Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 50/112 (44%), Positives = 69/112 (61%), Gaps = 12/112 (10%) Query: 2 TSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRN----------GAV 51 TS RWFH +++G EAE LL +G GSFL R S+S+PGDF LSVR V Sbjct: 6 TSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKV 65 Query: 52 THIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 TH+ I+ YD+ GGE+F +L +LV++Y ++ + E G V++LK PLN Sbjct: 66 THVMIRCQELKYDVGGGERFDSLTDLVEHYKKN--PMVETLGTVLQLKQPLN 115 >3PS5-A nrPDB Length = 595 Score = 664 bits (1714), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/547 (58%), Positives = 410/547 (74%), Gaps = 6/547 (1%) Query: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64 RWFH +++G++AE LL RGV GSFLARPS+ N GDF+LSVR VTHI+IQN+GD+YD Sbjct: 3 RWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62 Query: 65 LYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEK 124 LYGGEKFATL ELV+YY + G L++++G +I LKYPLNC+DPTSERW+HGH+SG +AE Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAET 122 Query: 125 LLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKYDVGG 183 LL KG+ +FLVRES S PGDFVLSV + D+ ++ G +VTH+ + C+ +Y VGG Sbjct: 123 LLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRYTVGG 180 Query: 184 GERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKV 243 E FDSLTDLVEH+KK + E G + L+QP TR+NAA+IE+RV EL+K E+ D Sbjct: 181 LETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTA 240 Query: 244 KQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSD 303 K GFWEEFE+LQ+QE K L+ R EGQR ENK KNRYKNILPFDH+RV+L D N P SD Sbjct: 241 KAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSD 300 Query: 304 YINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERG 363 YINAN I + N+K +YIA+QGCL+ TVNDFW+M +QENSRVIVMTT+EVE+G Sbjct: 301 YINANYIKNQLLGPDENAK---TYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKG 357 Query: 364 KSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTW 423 ++KCV YWP+ + YG V N E +Y LR L++S + G+ R +W Y + +W Sbjct: 358 RNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSW 417 Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKG 483 PDHGVPS+PGGVL FL++++ +QES+ AGP++VH SAGIGRTGT IVID+L++ I KG Sbjct: 418 PDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMENISTKG 477 Query: 484 VDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYT 543 +DCDID+ KTIQMVR+QRSGMVQTEAQY+FIY+A+ +IET ++++E Q K + EY Sbjct: 478 LDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYG 537 Query: 544 NIKYSLA 550 NI Y A Sbjct: 538 NITYPPA 544 Score = 69.7 bits (169), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 43/119 (36%), Positives = 65/119 (54%), Gaps = 16/119 (13%) Query: 2 TSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGA---------VT 52 TS RW+H +++G +AE LL +G +FL R S S PGDF LSV + VT Sbjct: 106 TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVT 165 Query: 53 HIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYP-----LNCAD 106 HIK+ G Y + G E F +L +LV+++ + ++E +G + L+ P +N AD Sbjct: 166 HIKVMCEGGRYTVGGLETFDSLTDLVEHFKK--TGIEEASGAFVYLRQPYYATRVNAAD 222 >2B3O-A nrPDB Length = 532 Score = 658 bits (1698), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/533 (58%), Positives = 404/533 (75%), Gaps = 6/533 (1%) Query: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64 RWFH +++G++AE LL RGV GSFLARPS+ N GDF+LSVR VTHI+IQN+GD+YD Sbjct: 3 RWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62 Query: 65 LYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEK 124 LYGGEKFATL ELV+YY + G L++++G +I LKYPLNC+DPTSERW+HGH+SG +AE Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAET 122 Query: 125 LLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKYDVGG 183 LL KG+ +FLVRES S PGDFVLSV + D+ ++ G +VTH+ + C+ +Y VGG Sbjct: 123 LLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRYTVGG 180 Query: 184 GERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKV 243 E FDSLTDLVEH+KK + E G + L+QP TR+NAA+IE+RV EL+K E+ D Sbjct: 181 LETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTA 240 Query: 244 KQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSD 303 K GFWEEFE+LQ+QE K L+ R EGQR ENK KNRYKNILPFDH+RV+L D N P SD Sbjct: 241 KAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSD 300 Query: 304 YINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERG 363 YINAN I + N+K +YIA+QGCL+ TVNDFW+M +QENSRVIVMTT+EVE+G Sbjct: 301 YINANYIKNQLLGPDENAK---TYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKG 357 Query: 364 KSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTW 423 ++KCV YWP+ + YG V N E +Y LR L++S + G+ R +W Y + +W Sbjct: 358 RNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSW 417 Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKG 483 PDHGVPS+PGGVL FL++++ +QES+ AGP++VHCSAGIGRTGT IVID+L++ I KG Sbjct: 418 PDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKG 477 Query: 484 VDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK 536 +DCDID+ KTIQMVR+QRSGMVQTEAQY+FIY+A+ +IET ++++E Q K Sbjct: 478 LDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQK 530 Score = 69.3 bits (168), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 43/119 (36%), Positives = 65/119 (54%), Gaps = 16/119 (13%) Query: 2 TSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGA---------VT 52 TS RW+H +++G +AE LL +G +FL R S S PGDF LSV + VT Sbjct: 106 TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVT 165 Query: 53 HIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYP-----LNCAD 106 HIK+ G Y + G E F +L +LV+++ + ++E +G + L+ P +N AD Sbjct: 166 HIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTG--IEEASGAFVYLRQPYYATRVNAAD 222 >4PVG-A nrPDB Length = 298 Score = 614 bits (1583), Expect = e-176, Method: Compositional matrix adjust. Identities = 290/291 (99%), Positives = 291/291 (100%) Query: 240 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE 299 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE Sbjct: 2 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE 61 Query: 300 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE 359 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE Sbjct: 62 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE 121 Query: 360 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH 419 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH Sbjct: 122 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH 181 Query: 420 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII 479 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII Sbjct: 182 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII 241 Query: 480 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIE 530 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRR+E Sbjct: 242 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRLE 292 >4HJQ-A nrPDB Length = 308 Score = 365 bits (937), Expect = e-101, Method: Compositional matrix adjust. Identities = 170/285 (59%), Positives = 219/285 (76%), Gaps = 3/285 (1%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYI 305 GFWEEFE+LQ+QE K L+ R EGQR ENK KNRYKNILPFDH+RV+L D N P SDYI Sbjct: 23 GFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYI 82 Query: 306 NANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKS 365 NAN I + N+K +YIA+QGCL+ TVNDFW+M +QENSRVIVMTT+EVE+G++ Sbjct: 83 NANYIKNQLLGPDENAK---TYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRN 139 Query: 366 KCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPD 425 KCV YWP+ + YG V N E +Y LR L++S + G+ R +W Y + +WPD Sbjct: 140 KCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPD 199 Query: 426 HGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVD 485 HGVPS+PGGVL FL++++ +QES+ AGP++VH SAGIGRTGT IVID+L++ I KG+D Sbjct: 200 HGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMENISTKGLD 259 Query: 486 CDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIE 530 CDID+ KTIQMVR+QRSGMVQTEAQY+FIY+A+ +IET ++++E Sbjct: 260 CDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLE 304 >2OOQ-A nrPDB Length = 286 Score = 213 bits (543), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 120/275 (43%), Positives = 170/275 (61%), Gaps = 24/275 (8%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRV--VLHDGDPNEPVSD 303 GF EE+E L + + + KE EN+NKNRY NI+ +DH+RV ++ DGDP+ SD Sbjct: 23 GFKEEYEALPEGQTASWDTAKE---DENRNKNRYGNIISYDHSRVRLLVLDGDPH---SD 76 Query: 304 YINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERG 363 YINAN I + + YIATQG +Q TV DFWRM++QENS IVM T VE G Sbjct: 77 YINANYI--------DGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVG 128 Query: 364 KSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTW 423 + KCV+YWPD+ + YG ++V ++ +Y +R + K G R + +HF +W Sbjct: 129 RVKCVRYWPDDTEV--YGDIKVTLIETEPLAEYVIRTFTVQKKGYHEI-RELRLFHFTSW 185 Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKG 483 PDHGVP G+L F+ +V K + +AGP+VVHCSAG GRTG FI ID ++D+ +G Sbjct: 186 PDHGVPCYATGLLGFVRQV--KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEG 243 Query: 484 VDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 V +D+ ++ +R+QR +VQTE QY F++ A+ Sbjct: 244 V---VDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 275 >2C7S-A nrPDB Length = 313 Score = 213 bits (543), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 122/283 (43%), Positives = 170/283 (60%), Gaps = 22/283 (7%) Query: 236 LAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDG 295 L +T+D GF EE+E+ + + S ++ +N+ KNRY NI+ +DH+RV+L Sbjct: 37 LMKTSDS--YGFKEEYESFFEGQSA---SWDVAKKDQNRAKNRYGNIIAYDHSRVILQPV 91 Query: 296 DPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVM 355 + ++P SDYINAN I + + YIATQG + TV DFWRM++QE S IVM Sbjct: 92 E-DDPSSDYINANYI--------DGYQRPSHYIATQGPVHETVYDFWRMIWQEQSACIVM 142 Query: 356 TTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTV 415 T VE G+ KC KYWPD+ + YG +V V+ +Y +R L + G N R V Sbjct: 143 VTNLVEVGRVKCYKYWPDDTEV--YGDFKVTCVEMEPLAEYVVRTFTLERRGY-NEIREV 199 Query: 416 WQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDIL 475 Q+HF WPDHGVP G+L F+ V K + AGP+VVHCSAG GRTG +IVIDI+ Sbjct: 200 KQFHFTGWPDHGVPYHATGLLSFIRRV--KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIM 257 Query: 476 IDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 +D+ +GV +D+ ++ +RS+R MVQTE QY FI+ A+ Sbjct: 258 LDMAEREGV---VDIYNCVKALRSRRINMVQTEEQYIFIHDAI 297 >1YFO-A nrPDB Length = 302 Score = 213 bits (542), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 122/282 (43%), Positives = 171/282 (60%), Gaps = 25/282 (8%) Query: 247 FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE--PVSDY 304 F EEF L C + + + ++ENK KNRY NILP+DH+RV L P E P SDY Sbjct: 31 FREEFNALP--ACPIQATCEAASKEENKEKNRYVNILPYDHSRVHL---TPVEGVPDSDY 85 Query: 305 INANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGK 364 INA+ I N + K +IA QG + TVNDFWRM++++N+ IVM T ER + Sbjct: 86 INASFI--------NGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKE 137 Query: 365 SKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNT---ERTVWQYHFR 421 KC +YWPD+ YG +RV + DYT+R+ + +VG +R + Q+HF Sbjct: 138 CKCAQYWPDQ-GCWTYGNVRVSVEDVTVLVDYTVRKFCIQQVGDVTNRKPQRLITQFHFT 196 Query: 422 TWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIRE 481 +WPD GVP P G+L FL++V K + AG +VVHCSAG+GRTGTF+VID ++D++ Sbjct: 197 SWPDFGVPFTPIGMLKFLKKV--KACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHS 254 Query: 482 KGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMA-VQHYI 522 + +DV + +R+QR MVQT+ QY FIY A ++HY+ Sbjct: 255 ER---KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL 293 >1RPM-A nrPDB Length = 278 Score = 206 bits (523), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 119/275 (43%), Positives = 164/275 (59%), Gaps = 24/275 (8%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLH--DGDPNEPVSD 303 GF EE+E+ + + S K + EN+ KNRY NI+ +DH+RV L +GD N SD Sbjct: 21 GFKEEYESFFEGQSAPWDSAK---KDENRMKNRYGNIIAYDHSRVRLQTIEGDTN---SD 74 Query: 304 YINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERG 363 YIN N I + YIATQG +Q T+ DFWRMV+ EN+ I+M T VE G Sbjct: 75 YINGNYI--------DGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVG 126 Query: 364 KSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTW 423 + KC KYWPD+ + Y ++V ++ +Y +R + K G R + Q+HF W Sbjct: 127 RVKCCKYWPDDTEI--YKDIKVTLIETELLAEYVIRTFAVEKRGVHEI-REIRQFHFTGW 183 Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKG 483 PDHGVP G+L F+ +V K +S AGP+VVHCSAG GRTG FIVIDI++D+ +G Sbjct: 184 PDHGVPYHATGLLGFVRQV--KSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREG 241 Query: 484 VDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 V +D+ ++ +RS+R MVQTE QY FI+ A+ Sbjct: 242 V---VDIYNCVRELRSRRVNMVQTEEQYVFIHDAI 273 >6D4D-A nrPDB Length = 292 Score = 204 bits (519), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 124/285 (43%), Positives = 168/285 (58%), Gaps = 20/285 (7%) Query: 239 TTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPN 298 + D KQ F EEF +L + + ++EN+ KNRY NILP DH+RV+L D Sbjct: 22 SADDCKQ-FREEFNSLPSGHIQGTFEL--ANKEENREKNRYPNILPNDHSRVILSQLD-G 77 Query: 299 EPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTK 358 P SDYINA+ I + K K +IA QG Q TVNDFWRMV+++ S IVM T Sbjct: 78 IPCSDYINASYI--------DGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTN 129 Query: 359 EVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLS-KVGQG-NTERTVW 416 ER + KC +YWPD+ YG +RV DYT+R+ + ++ G R V Sbjct: 130 LKERKEEKCHQYWPDQ-GCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVS 188 Query: 417 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 Q HF +WPD GVP P G+L FL++V K + + AGP+VVHCSAG+GRTGTFIVID ++ Sbjct: 189 QLHFTSWPDFGVPFTPIGMLKFLKKV--KTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMM 246 Query: 477 DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHY 521 ++ + +DV + + +R+QR MVQT+ QY FIY A+ Y Sbjct: 247 AMMHAEQ---KVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEY 288 >2JJD-A nrPDB Length = 599 Score = 204 bits (518), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 124/285 (43%), Positives = 168/285 (58%), Gaps = 20/285 (7%) Query: 239 TTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPN 298 + D KQ F EEF +L + + ++EN+ KNRY NILP DH+RV+L D Sbjct: 23 SADDCKQ-FREEFNSLPSGHIQGTFEL--ANKEENREKNRYPNILPNDHSRVILSQLD-G 78 Query: 299 EPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTK 358 P SDYINA+ I + K K +IA QG Q TVNDFWRMV+++ S IVM T Sbjct: 79 IPCSDYINASYI--------DGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTN 130 Query: 359 EVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLS-KVGQG-NTERTVW 416 ER + KC +YWPD+ YG +RV DYT+R+ + ++ G R V Sbjct: 131 LKERKEEKCHQYWPDQ-GCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVS 189 Query: 417 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 Q HF +WPD GVP P G+L FL++V K + + AGP+VVHCSAG+GRTGTFIVID ++ Sbjct: 190 QLHFTSWPDFGVPFTPIGMLKFLKKV--KTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMM 247 Query: 477 DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHY 521 ++ + +DV + + +R+QR MVQT+ QY FIY A+ Y Sbjct: 248 AMMH---AEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEY 289 Score = 167 bits (424), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 101/311 (32%), Positives = 168/311 (54%), Gaps = 21/311 (6%) Query: 219 TRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNR 278 T ++ + +E ++ + DK+ G EEF L + + + G N K R Sbjct: 295 TELDVSSLEKHLQTMHGTTTHFDKI--GLEEEFRKLTNVRI-MKENMRTGNLPANMKKAR 351 Query: 279 YKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTV 338 I+P+D RV+L E +DYINA+ I + + K +IATQG L +TV Sbjct: 352 VIQIIPYDFNRVILSMKRGQE-YTDYINASFI--------DGYRQKDYFIATQGPLAHTV 402 Query: 339 NDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTL 398 DFWRM+++ S IVM T+ ER + KC +YWP E ++ +G + + ++ + ++ Sbjct: 403 EDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVT-HGEITIEIKNDTLSEAISI 461 Query: 399 RELKLS----KVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGP 454 R+ ++ + QG R V Q+HF WP+ G+P++ G++D + V +Q+ + P Sbjct: 462 RDFLVTLNQPQARQGEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAVQKQQQQTGNH-P 520 Query: 455 VVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFI 514 + VHCSAG GRTGTFI + +++ ++ +G+ +DV + ++ +R QR MVQT QY F Sbjct: 521 ITVHCSAGAGRTGTFIALSNILERVKAEGL---LDVFQAVKSLRLQRPHMVQTLEQYEFC 577 Query: 515 YMAVQHYIETL 525 Y VQ +I+ Sbjct: 578 YKVVQDFIDIF 588 >4BPC-A nrPDB Length = 582 Score = 202 bits (513), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 107/258 (41%), Positives = 155/258 (60%), Gaps = 24/258 (9%) Query: 273 NKNKNRYKNILPFDHTRVVLHDGDPNEPV-----SDYINANIIMPEFETKCNNSKPKKSY 327 NK KNR NI+P++ TRV L +P+ SDYINA+ I + + +K+Y Sbjct: 339 NKFKNRLVNIMPYESTRVAL------QPIRGVEGSDYINASFI--------DGYRQQKAY 384 Query: 328 IATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRN 387 IATQG L T DFWRM+++ NS ++VM TK E G+ KC +YWP E + + Y V Sbjct: 385 IATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSAR-YQYFVVDP 443 Query: 388 VKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQE 447 + E Y LRE K++ G + RTV Q+ F WP+ GVP G +DF+ +VH +E Sbjct: 444 MAEYNMPQYILREFKVTDARDGQS-RTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKE 502 Query: 448 SIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQT 507 GP+ VHCSAG+GRTG FI + I+++ +R +GV +D+ +T++M+R+QR MVQT Sbjct: 503 QFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGV---VDIFQTVKMLRTQRPAMVQT 559 Query: 508 EAQYRFIYMAVQHYIETL 525 E +Y+F Y A Y+ + Sbjct: 560 EDEYQFAYQAALEYLGSF 577 Score = 192 bits (489), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 113/292 (38%), Positives = 171/292 (58%), Gaps = 27/292 (9%) Query: 233 LSKLAETTDKVKQG----FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHT 288 ++ +AE T+++K +E+E++ + ++ + + NK KNRY N++ +DH+ Sbjct: 9 IADMAEHTERLKANDSLKLSQEYESIDPGQQ---FTWEHSNLEVNKPKNRYANVIAYDHS 65 Query: 289 RVVLHDGDPNEPV--SDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVF 346 RV+L P E + SDYINAN + + + + +YIATQG L T DFWRMV+ Sbjct: 66 RVILQ---PIEGIMGSDYINANYV--------DGYRRQNAYIATQGPLPETFGDFWRMVW 114 Query: 347 QENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKV 406 ++ S IVM T+ E+ + KC +YWP+ + YG ++V + + +R L K Sbjct: 115 EQRSATIVMMTRLEEKSRIKCDQYWPNR-GTETYGFIQVTLLDTIELATFAVRTFSLHKN 173 Query: 407 GQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRT 466 G + +R V Q+ F WPDHGVP P L FL V K + DAGP+VVHCSAG+GRT Sbjct: 174 G-SSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRV--KTANPPDAGPIVVHCSAGVGRT 230 Query: 467 GTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 G FIVID +++ I+ + +DV + ++RSQR+ MVQTE QY FI+ A+ Sbjct: 231 GAFIVIDAMLERIKPEKT---VDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 279 >2NLK-A nrPDB Length = 627 Score = 199 bits (505), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 121/320 (37%), Positives = 184/320 (57%), Gaps = 30/320 (9%) Query: 236 LAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHD- 294 + E + GF E+FE +Q+ + + + ENK+KNRY NIL +DH+RV L Sbjct: 12 IGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPL 71 Query: 295 GDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIV 354 + SDYINAN + + K+YIATQG L++T DFWRM++++N+ +IV Sbjct: 72 PGKDSKHSDYINANYV--------DGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIV 123 Query: 355 MTTKEVERGKSKCVKYWPDEYALKEYG--VMRVRNVKESAAHD---YTLRELKLSKVGQG 409 M T VE+G+ KC +YWP E + +EYG ++ +++ K A + +++R K+ K +G Sbjct: 124 MITNLVEKGRRKCDQYWPTENS-EEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKG 182 Query: 410 N-----TERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIG 464 N ER V QYH+ WPD GVP VL F+ + + GPV+VHCSAG+G Sbjct: 183 NPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRR--SSAARMPETGPVLVHCSAGVG 240 Query: 465 RTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIET 524 RTGT+IVID ++ I++K ++V ++ +R+QR+ +VQTE QY FI+ A+ I Sbjct: 241 RTGTYIVIDSMLQQIKDKST---VNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILG 297 Query: 525 LQRRIEEEQKSKRKGHEYTN 544 +E + S + H Y N Sbjct: 298 -----KETEVSSNQLHSYVN 312 Score = 81.3 bits (199), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 67/267 (25%), Positives = 113/267 (42%), Gaps = 33/267 (12%) Query: 268 GQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSY 327 Q++ NK KNR +++P + RV L P +DYINA+ IM + + + Sbjct: 345 AQKECNKEKNRNSSVVPSERARVGLAPL-PGMKGTDYINASYIMGYYRSN--------EF 395 Query: 328 IATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDE----------YAL 377 I TQ L +T DFWRM++ N+++IVM + + V YWP L Sbjct: 396 IITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFV-YWPSREESMNCEAFTVTL 454 Query: 378 KEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLD 437 + + N ++ HD+ L + Q + V + WP+ P + Sbjct: 455 ISKDRLCLSNEEQIIIHDFIL------EATQDDYVLEVRHFQCPKWPNPDAPI--SSTFE 506 Query: 438 FLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMV 497 + + K+E++ GP +VH G G + L + + +DV + +M+ Sbjct: 507 LINVI--KEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENA---VDVFQVAKMI 561 Query: 498 RSQRSGMVQTEAQYRFIYMAVQHYIET 524 R G+ QY+FIY A+ + T Sbjct: 562 NLMRPGVFTDIEQYQFIYKAMLSLVST 588 >2PBN-A nrPDB Length = 313 Score = 197 bits (501), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 115/294 (39%), Positives = 175/294 (59%), Gaps = 25/294 (8%) Query: 236 LAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHD- 294 + E + GF E+FE +Q+ + + + ENK+KNRY NIL +DH+RV L Sbjct: 20 IGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPL 79 Query: 295 GDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIV 354 + SDYINAN + + K+YIATQG L++T DFWRM++++N+ +IV Sbjct: 80 PGKDSKHSDYINANYV--------DGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIV 131 Query: 355 MTTKEVERGKSKCVKYWPDEYALKEYG--VMRVRNVKESAAHD---YTLRELKLSKVGQG 409 M T VE+G+ KC +YWP E + +EYG ++ +++ K A + +++R K+ K +G Sbjct: 132 MITNLVEKGRRKCDQYWPTENS-EEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKG 190 Query: 410 N-----TERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIG 464 N ER V QYH+ WPD GVP VL F+ + + GPV+VHCSAG+G Sbjct: 191 NPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRR--SSAARMPETGPVLVHCSAGVG 248 Query: 465 RTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 RTGT+IVID ++ I++K ++V ++ +R+QR+ +VQTE QY FI+ A+ Sbjct: 249 RTGTYIVIDSMLQQIKDKST---VNVLGFLKHIRTQRNYLVQTEEQYIFIHDAL 299 >1LAR-A nrPDB Length = 575 Score = 194 bits (494), Expect = 8e-50, Method: Compositional matrix adjust. Identities = 105/255 (41%), Positives = 152/255 (59%), Gaps = 18/255 (7%) Query: 273 NKNKNRYKNILPFDHTRVVLHDGDPNEPV--SDYINANIIMPEFETKCNNSKPKKSYIAT 330 NK KNR NI+P++ TRV L P V SDYINA+ + + + +K+YIAT Sbjct: 332 NKFKNRLVNIMPYELTRVCLQ---PIRGVEGSDYINASFL--------DGYRQQKAYIAT 380 Query: 331 QGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKE 390 QG L + DFWRM+++ NS +IVM TK E G+ KC +YWP E + + Y V + E Sbjct: 381 QGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSAR-YQYFVVDPMAE 439 Query: 391 SAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIM 450 Y LRE K++ G + RT+ Q+ F WP+ GVP G +DF+ +VH +E Sbjct: 440 YNMPQYILREFKVTDARDGQS-RTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFG 498 Query: 451 DAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ 510 GP+ VHCSAG+GRTG FI + I+++ +R +GV +D+ +T++ +R+QR MVQTE Q Sbjct: 499 QDGPITVHCSAGVGRTGVFITLSIVLERMRYEGV---VDMFQTVKTLRTQRPAMVQTEDQ 555 Query: 511 YRFIYMAVQHYIETL 525 Y+ Y A Y+ + Sbjct: 556 YQLCYRAALEYLGSF 570 Score = 193 bits (490), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 23/290 (7%) Query: 233 LSKLAETTDKVKQG----FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHT 288 ++ LA+ +++K F +E+E++ + ++ + + NK KNRY N++ +DH+ Sbjct: 2 ITDLADNIERLKANDGLKFSQEYESIDPGQ---QFTWENSNLEVNKPKNRYANVIAYDHS 58 Query: 289 RVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQE 348 RV+L D P SDYINAN I + + + +YIATQG L T+ DFWRMV+++ Sbjct: 59 RVILTSID-GVPGSDYINANYI--------DGYRKQNAYIATQGPLPETMGDFWRMVWEQ 109 Query: 349 NSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQ 408 + +VM T+ E+ + KC +YWP + G+++V + YT+R L K G Sbjct: 110 RTATVVMMTRLEEKSRVKCDQYWPAR-GTETCGLIQVTLLDTVELATYTVRTFALHKSG- 167 Query: 409 GNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGT 468 + +R + Q+ F WPDHGVP P +L FL V K + +DAGP+VVHCSAG+GRTG Sbjct: 168 SSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRV--KACNPLDAGPMVVHCSAGVGRTGC 225 Query: 469 FIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 FIVID +++ ++ + +D+ + +RSQR+ MVQTE QY FI+ A+ Sbjct: 226 FIVIDAMLERMKHEKT---VDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 272 >1WCH-A nrPDB Length = 315 Score = 191 bits (486), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 126/329 (38%), Positives = 174/329 (52%), Gaps = 33/329 (10%) Query: 208 TVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGF-WEEFETLQQQECKLLYSRK 266 VL + + L + + A ++S +R L L + QG +E E LQ E K L Sbjct: 17 AVLPVVKVLPSGKYTGANLKSVIRVLRGLLD------QGIPSKELENLQ--ELKPLDQCL 68 Query: 267 EGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKS 326 GQ +EN+ KNRYKNILP+D TRV L D YINA+ I K K + Sbjct: 69 IGQTKENRRKNRYKNILPYDATRVPLGDE------GGYINASFI------KIPVGKEEFV 116 Query: 327 YIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVR 386 YIA QG L TV DFW+M++++ S VI M T+EVE K KC +YWP+ R+R Sbjct: 117 YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLR 176 Query: 387 --NVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHH 444 V+ + +R + L + Q R + +F WPDH PS P +L F+ + H Sbjct: 177 LALVRMQQLKGFVVRAMTLEDI-QTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRH 235 Query: 445 KQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGM 504 S GP++ HCSAGIGR+GT I ID+++ +I + D D D+ ++ +R QR GM Sbjct: 236 IHRS----GPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFDISDLVRCMRLQRHGM 288 Query: 505 VQTEAQYRFIYMAVQHYIETLQRRIEEEQ 533 VQTE QY F Y + + + LQ EEEQ Sbjct: 289 VQTEDQYIFCYQVILYVLTRLQA--EEEQ 315 >5AWX-A nrPDB Length = 298 Score = 191 bits (485), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 110/278 (39%), Positives = 162/278 (58%), Gaps = 22/278 (7%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHD-GDPNEPVSDY 304 GF EEFE +Q L + +NK+KNRY NI+ +DH+RV L + + ++DY Sbjct: 21 GFTEEFEEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQLAEKDGKLTDY 80 Query: 305 INANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGK 364 INAN + + K+YIA QG L++T DFWRM+++ N VIVM T VE+G+ Sbjct: 81 INANYV--------DGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGR 132 Query: 365 SKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKL--SKVGQGNTE-----RTVWQ 417 KC +YWP + +EYG V YT+R L +K+ +G+ + R V Q Sbjct: 133 RKCDQYWPAD-GSEEYGNFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVTQ 191 Query: 418 YHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 477 YH+ WPD GVP VL F+ + + + + GPVVVHCSAG+GRTGT+IV+D ++ Sbjct: 192 YHYTQWPDMGVPEYSLPVLTFVRKAAYAKRHAV--GPVVVHCSAGVGRTGTYIVLDSMLQ 249 Query: 478 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 515 I+ +G +++ ++ +RSQR+ +VQTE QY FI+ Sbjct: 250 QIQHEGT---VNIFGFLKHIRSQRNYLVQTEEQYVFIH 284 >2NV5-A nrPDB Length = 299 Score = 189 bits (481), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 110/290 (37%), Positives = 169/290 (58%), Gaps = 23/290 (7%) Query: 233 LSKLAETTDKVKQG----FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHT 288 + +LA+ +++K F +E+E++ + ++ + + NK KNRY N++ +DH+ Sbjct: 11 ILELADHIERLKANDNLKFSQEYESIDPGQ---QFTWEHSNLEVNKPKNRYANVIAYDHS 67 Query: 289 RVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQE 348 RV+L P SDY+NAN I + + + +YIATQG L T DFWRM++++ Sbjct: 68 RVLL-SAIEGIPGSDYVNANYI--------DGYRKQNAYIATQGSLPETFGDFWRMIWEQ 118 Query: 349 NSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQ 408 S +VM TK ER + KC +YWP + +G+++V + Y +R L K G Sbjct: 119 RSATVVMMTKLEERSRVKCDQYWPSR-GTETHGLVQVTLLDTVELATYCVRTFALYKNG- 176 Query: 409 GNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGT 468 + +R V Q+ F WPDHGVP P L FL V K + DAGP+VVHCSAG+GRTG Sbjct: 177 SSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRV--KTCNPPDAGPMVVHCSAGVGRTGC 234 Query: 469 FIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 FIVID +++ I+ + +D+ + ++R+QR+ MVQTE QY FI+ A+ Sbjct: 235 FIVIDAMLERIKHEKT---VDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 281 >4BJO-A nrPDB Length = 338 Score = 189 bits (481), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 97/250 (38%), Positives = 149/250 (59%), Gaps = 17/250 (6%) Query: 272 ENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQ 331 +NKN+NRY+++ PFDH+R+ LH D +DYINA++I E + ++SYI TQ Sbjct: 56 KNKNRNRYRDVSPFDHSRIKLHQED-----NDYINASLIKME--------EAQRSYILTQ 102 Query: 332 GCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWP---DEYALKEYGVMRVRNV 388 G L NT FW MV+++ SR +VM + +E+G KC +YWP ++ + E +++ + Sbjct: 103 GPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLI 162 Query: 389 KESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQES 448 E YT+R+L+L + T R + +H+ TWPD GVP P L+FL +V Sbjct: 163 SEDIKSYYTVRQLELENLTTQET-REILHFHYTTWPDFGVPESPASFLNFLFKVRESGSL 221 Query: 449 IMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTE 508 + GPVVVHCSAGIGR+GTF + D + ++ ++ +D+ K + +R R G++QT Sbjct: 222 SPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTA 281 Query: 509 AQYRFIYMAV 518 Q RF Y+AV Sbjct: 282 DQLRFSYLAV 291 >1L8K-A nrPDB Length = 314 Score = 189 bits (480), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 101/259 (38%), Positives = 152/259 (58%), Gaps = 21/259 (8%) Query: 263 YSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSK 322 Y + + EN+N+NRY+++ P+DH+RV L + + +DYINA+++ E + Sbjct: 32 YPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAE-----NDYINASLVDIE--------E 78 Query: 323 PKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWP---DEYALKE 379 ++SYI TQG L NT FW MV+Q+ ++ +VM + VE+ KC +YWP E KE Sbjct: 79 AQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKE 138 Query: 380 YGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFL 439 G V+ + E YT+ L+L + G T RT+ +H+ TWPD GVP P L+FL Sbjct: 139 TG-FSVKLLSEDVKSYYTVHLLQLENINSGET-RTISHFHYTTWPDFGVPESPASFLNFL 196 Query: 440 EEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRS 499 +V D GP V+HCSAGIGR+GTF ++D + ++ EKG DI++ + + +R Sbjct: 197 FKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCL-VLMEKGD--DINIKQVLLNMRK 253 Query: 500 QRSGMVQTEAQYRFIYMAV 518 R G++QT Q RF YMA+ Sbjct: 254 YRMGLIQTPDQLRFSYMAI 272 >3I36-A nrPDB Length = 342 Score = 187 bits (476), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 114/277 (41%), Positives = 158/277 (57%), Gaps = 25/277 (9%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVL----HDGDPNEPV 301 GF EE+E L+ L + + EN+ KNRY N+LP+D +RV L H D Sbjct: 45 GFAEEYEDLKLIGISL--PKYAAEIAENRGKNRYNNVLPYDISRVKLSVQTHSTD----- 97 Query: 302 SDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVE 361 DYINAN MP + +K K +IATQG L NT+ DFWRMV+++N IVM TK VE Sbjct: 98 -DYINANY-MPGYHSK-------KDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVE 148 Query: 362 RGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFR 421 +G++KC +YWP + A ++YG + V E ++T+R+ + K Q + + Q+HF Sbjct: 149 QGRTKCEEYWPSKQA-QDYGDITVAMTSEVVLPEWTIRDF-VVKNMQSSESHPLRQFHFT 206 Query: 422 TWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIRE 481 +WPDHGVP +++F V + I P++VHCSAG+GRTGTFI ID LI I Sbjct: 207 SWPDHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIEN 266 Query: 482 KGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 + +DV + +R R MVQTE QY F+ V Sbjct: 267 ENT---VDVYGIVYDLRMHRPLMVQTEDQYVFLNQCV 300 >5HDE-A nrPDB Length = 307 Score = 184 bits (466), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 102/264 (38%), Positives = 147/264 (55%), Gaps = 17/264 (6%) Query: 262 LYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNS 321 +Y G+++EN KNRYK+ILPFDH+RV L P++ SDYINAN I Sbjct: 53 IYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQD-SDYINANFI--------KGV 103 Query: 322 KPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWP--DEYALKE 379 K+Y+ATQG L NTV DFWRM+++ N +IVM +E E G+ KC +YWP E + Sbjct: 104 YGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPIT- 162 Query: 380 YGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFL 439 + ++ E A DY +R L L N R ++Q+H+ WPDH VPS +LD + Sbjct: 163 FAPFKISCEDEQARTDYFIRTLLLEF---QNESRRLYQFHYVNWPDHDVPSSFDSILDMI 219 Query: 440 EEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRS 499 + QE + P+ +HCSAG GRTG ID ++++ + + +V IQ +R+ Sbjct: 220 SLMRKYQEH--EDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRT 277 Query: 500 QRSGMVQTEAQYRFIYMAVQHYIE 523 QR VQT+ QY ++ A+ E Sbjct: 278 QRHSAVQTKEQYELVHRAIAQLFE 301 >2H03-A nrPDB Length = 291 Score = 182 bits (462), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 101/257 (39%), Positives = 145/257 (56%), Gaps = 17/257 (6%) Query: 272 ENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQ 331 EN+ KNRY NILP+D TRV L G SDYINA+ I NN + + YI TQ Sbjct: 52 ENRGKNRYNNILPYDATRVKLSGG------SDYINASYI------PGNNFR--REYIVTQ 97 Query: 332 GCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKES 391 G L T +DFW+MV+++N IVM T+ VE+G+ KC YWP + YG + ++ + ES Sbjct: 98 GPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSES 157 Query: 392 AAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMD 451 ++T+RE K+ Q + R + +H+ WPDHGVP ++ F+ V Sbjct: 158 VLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPG 217 Query: 452 AGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQY 511 AGP VVHCSAG+GRTGTFI +D ++ + K +D+ + +R R MVQTE QY Sbjct: 218 AGPTVVHCSAGVGRTGTFIALDRILQQLDSKD---SVDIYGAVHDLRLHRVHMVQTECQY 274 Query: 512 RFIYMAVQHYIETLQRR 528 +++ V+ + + R Sbjct: 275 VYLHQCVRDVLRARKLR 291 >6H8S-A nrPDB Length = 301 Score = 181 bits (458), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 104/247 (42%), Positives = 140/247 (56%), Gaps = 17/247 (6%) Query: 276 KNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQ 335 KNRYK ILP H+RV L DP +P+S YINAN I S +K YIATQG + Sbjct: 63 KNRYKTILPNPHSRVRLTSPDPEDPLSSYINANYIR-------GYSGEEKVYIATQGPIV 115 Query: 336 NTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHD 395 +TV DFWRMV+QE + +IVM T +E KC +YWP+E + + + V+ V + D Sbjct: 116 STVADFWRMVWQERTPIIVMITN-IEEMNEKCTEYWPEEQVVHDGVEITVQKVIHT--ED 172 Query: 396 YTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHH-KQESIMDAGP 454 Y LR + L + G ERT+ Y F +WPD P +L + EV Q+ P Sbjct: 173 YRLRLISLRR---GTEERTLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCSP 229 Query: 455 VVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFI 514 ++VHCSAGIGRTG FI I +R +GV +D+ KT +R R GM+QT QY+F+ Sbjct: 230 IIVHCSAGIGRTGCFIATSICCQQLRREGV---VDILKTTCQLRQDRGGMIQTCEQYQFV 286 Query: 515 YMAVQHY 521 + A+ Y Sbjct: 287 HHAMSLY 293 >1P15-A nrPDB Length = 253 Score = 180 bits (457), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 100/262 (38%), Positives = 152/262 (58%), Gaps = 19/262 (7%) Query: 266 KEGQRQENKNKNRYKNILPFDHTRVVL--HDGDPNEPVSDYINANIIMPEFETKCNNSKP 323 + G N KNR I+P++ RV++ G+ N +DY+NA+ I + + Sbjct: 2 RTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEEN---TDYVNASFI--------DGYRQ 50 Query: 324 KKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVM 383 K SYIA+QG L +T+ DFWRM+++ S IVM T+ ERG+ KC +YWP + L YG + Sbjct: 51 KDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD-GLVSYGDI 109 Query: 384 RVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVH 443 V KE YT+R+L ++ + N R + Q+HF WP+ G+PSD G+++ + V Sbjct: 110 TVELKKEEECESYTVRDLLVTNTRE-NKSRQIRQFHFHGWPEVGIPSDGKGMINIIAAV- 167 Query: 444 HKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSG 503 KQ+ P+ VHCSAG GRTGTF + +++ ++ +G+ +DV +T++ +R QR Sbjct: 168 QKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPH 224 Query: 504 MVQTEAQYRFIYMAVQHYIETL 525 MVQT QY F Y VQ YI+ Sbjct: 225 MVQTLEQYEFCYKVVQEYIDAF 246 >2CFV-A nrPDB Length = 316 Score = 179 bits (453), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 109/277 (39%), Positives = 156/277 (56%), Gaps = 25/277 (9%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVL----HDGDPNEPV 301 GF EE+E L+ + + + EN+ KNRY N+LP+D +RV L H D Sbjct: 45 GFAEEYEDLKL--VGISQPKYAAELAENRGKNRYNNVLPYDISRVKLSVQTHSTD----- 97 Query: 302 SDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVE 361 DYINAN MP + +K K +IATQG L NT+ DFWRMV+++N I+M TK VE Sbjct: 98 -DYINANY-MPGYHSK-------KDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVE 148 Query: 362 RGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFR 421 +G++KC +YWP + A ++YG + V E ++T+R+ + + Q + + Q+HF Sbjct: 149 QGRTKCEEYWPSKQA-QDYGDITVAMTSEIVLPEWTIRDFTVKNI-QTSESHPLRQFHFT 206 Query: 422 TWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIRE 481 + PDHGVP +++F V + P++VHCSAG+GRTGTFI ID LI I Sbjct: 207 SAPDHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIEN 266 Query: 482 KGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 + +DV + +R R MVQTE QY F+ V Sbjct: 267 ENT---VDVYGIVYDLRMHRPLMVQTEDQYVFLNQCV 300 >3OLR-A nrPDB Length = 313 Score = 178 bits (452), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 111/300 (37%), Positives = 165/300 (55%), Gaps = 26/300 (8%) Query: 237 AETTDKVKQGFWEEFETLQQQECKL----LYSRKEGQRQENKNKNRYKNILPFDHTRVVL 292 A++ K+ F EF L++Q K Y ++ +N KNRYK+ILP+D++RV L Sbjct: 33 AQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVEL 92 Query: 293 HDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRV 352 +E S YINAN I K+YIATQG L T+ DFWRM+++ + + Sbjct: 93 SLITSDED-SSYINANFI--------KGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLI 143 Query: 353 IVMTTKEVERGKSKCVKYW--PDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGN 410 IVM E E GK KC +YW P E L E+G V E DY +R LK+ + N Sbjct: 144 IVMACMEYEMGKKKCERYWAEPGEMQL-EFGPFSVSCEAEKRKSDYIIRTLKV----KFN 198 Query: 411 TE-RTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTF 469 +E RT++Q+H++ WPDH VPS +L+ + +V QE D+ P+ +H SAG GRTG Sbjct: 199 SETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQED--DSVPICIHSSAGCGRTGVI 256 Query: 470 IVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRI 529 ID ++++ + + V I+ +R+QR +VQT+ QY +Y AV +E +R++ Sbjct: 257 CAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAV---LELFKRQM 313 >3S3F-A nrPDB Length = 307 Score = 176 bits (447), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 103/281 (36%), Positives = 158/281 (56%), Gaps = 27/281 (9%) Query: 247 FWEEFETLQQ----QECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVS 302 F EEFE L+ Q C N+ KNR+ NILP+DH+R L D +E S Sbjct: 46 FSEEFEELKHVGRDQPCTF------ADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEG-S 98 Query: 303 DYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVER 362 DYINAN + ++ P++ +I TQG L +T +DFWRM ++ NSR IVM T+ E+ Sbjct: 99 DYINANYVP-------GHNSPRE-FIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEK 150 Query: 363 GKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRT 422 G+ KC +YWP++ YG ++V+ + +S D+ + E L + G+ +R + +HF T Sbjct: 151 GREKCDQYWPNDTVPVFYGDIKVQILNDSHYADWVMTEFMLCR---GSEQRILRHFHFTT 207 Query: 423 WPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREK 482 WPD GVP+ P ++ F+ + + + P+VVHCSAG+GR+GTFI +D ++ I Sbjct: 208 WPDFGVPNPPQTLVRFVRAFRDRIGA--EQRPIVVHCSAGVGRSGTFITLDRILQQINTS 265 Query: 483 GVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE 523 +D+ + +R +R MVQTE QY I+ + +E Sbjct: 266 DY---VDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLE 303 >2PI7-A nrPDB Length = 312 Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 102/249 (40%), Positives = 145/249 (58%), Gaps = 19/249 (7%) Query: 273 NKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQG 332 N+ KNRY NILP+D +RV L + E SDYINAN I P + + + YIATQG Sbjct: 58 NRCKNRYTNILPYDFSRVRLVSMNEEEG-SDYINANYI-PGYNSP-------QEYIATQG 108 Query: 333 CLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESA 392 L T NDFW+MV Q+ S++IVM T+ E+ + KC YWP YG + V + E Sbjct: 109 PLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEDPIAYGDITVEMLSEEE 168 Query: 393 AHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGG--VLDFLEEVHHKQESIM 450 D+ R ++S + + V +++ WPDHGVP+ +L F++ V +Q+S+ Sbjct: 169 HTDWVYRNFRIS---YADEVQDVMHFNYTAWPDHGVPTANAAESILQFVQMV--RQKSVK 223 Query: 451 DAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ 510 GP+++HCSAG+GRTGTFI +D L+ IR+ +D+ + +RS R MVQTE Q Sbjct: 224 SKGPMIIHCSAGVGRTGTFIALDWLLQHIRDHEF---VDILGLVSDMRSYRMSMVQTEEQ 280 Query: 511 YRFIYMAVQ 519 Y FI+ VQ Sbjct: 281 YIFIHQCVQ 289 >5OVR-A nrPDB Length = 305 Score = 176 bits (445), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 101/247 (40%), Positives = 138/247 (55%), Gaps = 17/247 (6%) Query: 276 KNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQ 335 KNRYK ILP H+RV L DP++P+S YINAN I +K YIATQG + Sbjct: 67 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR-------GYGGEEKVYIATQGPIV 119 Query: 336 NTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHD 395 +TV DFWRMV+QE++ +IVM T +E KC +YWP+E + + V+ V + D Sbjct: 120 STVADFWRMVWQEHTPIIVMITN-IEEMNEKCTEYWPEEQVAYDGVEITVQKVIHT--ED 176 Query: 396 YTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHH-KQESIMDAGP 454 Y LR + L G ER + Y F +WPD P +L + EV Q+ P Sbjct: 177 YRLRLISLKS---GTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAP 233 Query: 455 VVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFI 514 ++VHCSAGIGRTG FI I +R++GV +D+ KT +R R GM+QT QY+F+ Sbjct: 234 IIVHCSAGIGRTGCFIATSICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFV 290 Query: 515 YMAVQHY 521 + + Y Sbjct: 291 HHVMSLY 297 >2I75-A nrPDB Length = 320 Score = 175 bits (443), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 101/263 (38%), Positives = 143/263 (54%), Gaps = 22/263 (8%) Query: 262 LYSRKEGQRQ------ENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFE 315 LY +K G +N +KNRY++I P+D TRV+L + DYINAN I E Sbjct: 54 LYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGNE------DYINANYINMEIP 107 Query: 316 TKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEY 375 + S YIA QG L +T DFW+M +++ S ++VM T +VERG+ KC +YWP+ Sbjct: 108 S----SSIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPT 163 Query: 376 ALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGV 435 YG +V E Y R++ L + N R + Q + WPDHGVP D Sbjct: 164 GSSSYGCYQVTCHSEEGNTAYIFRKMTLFN-QEKNESRPLTQIQYIAWPDHGVPDDSSDF 222 Query: 436 LDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQ 495 LDF+ V +K+ PVVVHCSAGIGRTG I ++ + +I +D+ +T+ Sbjct: 223 LDFVCHVRNKRAG--KEEPVVVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTM- 279 Query: 496 MVRSQRSGMVQTEAQYRFIYMAV 518 R QR+ M+QT +QYRF+ A+ Sbjct: 280 --RDQRAMMIQTPSQYRFVCEAI 300 >2A8B-A nrPDB Length = 283 Score = 174 bits (440), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 102/247 (41%), Positives = 142/247 (57%), Gaps = 16/247 (6%) Query: 275 NKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCL 334 KNRYK ILP +RV L + + +S YINAN I S +K++IATQG + Sbjct: 45 TKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIR-------GYSGKEKAFIATQGPM 97 Query: 335 QNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAH 394 NTV+DFW+MV+QE+S VIVM TK E+ + KCV YWP++ + YG + V + + Sbjct: 98 INTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWPEKRGI--YGKVEVLVISVNECD 154 Query: 395 DYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGP 454 +YT+R L L QG+ + V Y + +WPDH P +L + +V + + GP Sbjct: 155 NYTIRNLVLK---QGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGP 211 Query: 455 VVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFI 514 VVVHCSAGIGRTG FI I ++E+GV +D + +R R GMVQT QY F+ Sbjct: 212 VVVHCSAGIGRTGCFIATSIGCQQLKEEGV---VDALSIVCQLRMDRGGMVQTSEQYEFV 268 Query: 515 YMAVQHY 521 + A+ Y Sbjct: 269 HHALCLY 275 >2GJT-A nrPDB Length = 295 Score = 173 bits (438), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 99/249 (39%), Positives = 142/249 (57%), Gaps = 19/249 (7%) Query: 273 NKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQG 332 N+ KNRY NILP+D +RV L + E +DYINAN I P + + + YIATQG Sbjct: 49 NRCKNRYTNILPYDFSRVRLVSMNEEEG-ADYINANYI-PGYNSP-------QEYIATQG 99 Query: 333 CLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESA 392 L T NDFW+MV Q+ S++IVM T+ E+ + KC YWP YG + V + E Sbjct: 100 PLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEE 159 Query: 393 AHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGG--VLDFLEEVHHKQESIM 450 D+ R ++ + + V +++ WPDHGVP+ +L F+ V +Q++ Sbjct: 160 QDDWACRHF---RINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMV--RQQATK 214 Query: 451 DAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ 510 GP+++HCSAG+GRTGTFI +D L+ IR+ +D+ + +RS R MVQTE Q Sbjct: 215 SKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEF---VDILGLVSEMRSYRMSMVQTEEQ 271 Query: 511 YRFIYMAVQ 519 Y FI+ VQ Sbjct: 272 YIFIHQCVQ 280 >4GFV-A nrPDB Length = 297 Score = 172 bits (436), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 100/261 (38%), Positives = 143/261 (54%), Gaps = 16/261 (6%) Query: 268 GQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSY 327 G R EN KNRYK++LP+D TRV+L E SDYIN N I +Y Sbjct: 48 GSRPENVRKNRYKDVLPYDQTRVILSLLQ-EEGHSDYINGNFI--------RGVDGSLAY 98 Query: 328 IATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRN 387 IATQG L +T+ DFWR+V++ +VI+M +E+E G+ +C +YW E + G+ + Sbjct: 99 IATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITL 158 Query: 388 VKESAAH-DYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQ 446 +KE + D LR LK++ + R+V+Q + +WPD GVPS P +L +EE Q Sbjct: 159 IKEKWLNEDIMLRTLKVTFQKES---RSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQ 215 Query: 447 ESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQ 506 S P+ VH SAG GRTG +D + ++ + + D + + +R QR VQ Sbjct: 216 GS--GPEPLCVHSSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQ 273 Query: 507 TEAQYRFIYMAV-QHYIETLQ 526 TE QYRF+Y V Q + TLQ Sbjct: 274 TEEQYRFLYHTVAQMFCSTLQ 294 >1YGU-A nrPDB Length = 610 Score = 171 bits (433), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 122/353 (34%), Positives = 188/353 (53%), Gaps = 43/353 (12%) Query: 247 FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLH--DGDPNEPVSDY 304 F EF+++ + K + KE ++ N+NKNRY +ILP+D+ RV L +GD S+Y Sbjct: 30 FLAEFQSIPRVFSK--FPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAG---SNY 84 Query: 305 INANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGK 364 INA+ I + K + YIA QG TV+DFWRM++++ + VIVM T+ E + Sbjct: 85 INASYI--------DGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNR 136 Query: 365 SKCVKYWPD-EYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTW 423 +KC +YWP E + +G + V+ + DY +++L + + T R V F +W Sbjct: 137 NKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSW 196 Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKG 483 PDHGVP DP +L V+ S +GP+VVH SAG+GRTGT+I ID +++ G Sbjct: 197 PDHGVPEDPHLLLKLRRRVN--AFSNFFSGPIVVHSSAGVGRTGTYIGIDAMLE-----G 249 Query: 484 VDCD--IDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHE 541 ++ + +DV + +R QR MVQ EAQY I+ A+ Y + E + + + H Sbjct: 250 LEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY-----NQFGETEVNLSELHP 304 Query: 542 YTNIKYSLADQTSGDQSPLPPCTPTPPCAEM-REDSARVY--ENVGLMQQQKS 591 Y L + D PP P+P AE R S R + +++G ++ KS Sbjct: 305 Y------LHNMKKRD----PPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKS 347 Score = 121 bits (303), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 80/280 (28%), Positives = 138/280 (49%), Gaps = 52/280 (18%) Query: 268 GQRQENKNKNRYKNILPFDHTRVVL-HDGDPNEPV-----------------SDYINANI 309 G ++ENK+KNR N++P+D+ RV L H+ + ++ S YINA+ Sbjct: 340 GNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASF 399 Query: 310 IMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVK 369 IM ++ + IA QG L+ T+ DFW+M+FQ +VIVM T+ + C + Sbjct: 400 IMSYWKPEV--------MIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQ 451 Query: 370 YWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVP 429 YW + + YG + V + YTLR +L + ++ RTV+QY + W +P Sbjct: 452 YWGE--GKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDS-RTVYQYQYTNWSVEQLP 508 Query: 430 SDPGGVLDFLEEV--------------HHKQESIMDAGPVVVHCSAGIGRTGTFIVIDIL 475 ++P ++ ++ V HHK + P+++HC G +TG F L Sbjct: 509 AEPKELISMIQVVKQKLPQKNSSEGNKHHK------STPLLIHCRDGSQQTGIFCA---L 559 Query: 476 IDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 515 ++++ + +D+ + ++ +R R GMV T QY+F+Y Sbjct: 560 LNLLESAETEEVVDIFQVVKALRKARLGMVSTFEQYQFLY 599 >2QEP-A nrPDB Length = 304 Score = 171 bits (433), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 102/259 (39%), Positives = 148/259 (57%), Gaps = 15/259 (5%) Query: 268 GQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSY 327 QR+EN KNR +L +DH+RV+L + + SDYINA+ IM ++ +Y Sbjct: 52 AQREENVPKNRSLAVLTYDHSRVLL-KAENSHSHSDYINASPIM-------DHDPRNPAY 103 Query: 328 IATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRN 387 IATQG L TV DFW+MV++ VIVM T E G +C YWPDE + Y + V Sbjct: 104 IATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGS-NLYHIYEVNL 162 Query: 388 VKESA-AHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQ 446 V E D+ +R L + Q N RTV Q+HF +W D GVPS +LDF +V+ Sbjct: 163 VSEHIWCEDFLVRSFYLKNL-QTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCY 221 Query: 447 ESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQ 506 + P++VHCS G GR+GT+++ID++++ + KG +ID+ T++ +R QR GMVQ Sbjct: 222 RG--RSCPIIVHCSDGAGRSGTYVLIDMVLNKM-AKGAK-EIDIAATLEHLRDQRPGMVQ 277 Query: 507 TEAQYRFIYMAVQHYIETL 525 T+ Q+ F AV + + Sbjct: 278 TKEQFEFALTAVAEEVNAI 296 >2I1Y-A nrPDB Length = 301 Score = 168 bits (426), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 110/323 (34%), Positives = 171/323 (52%), Gaps = 29/323 (8%) Query: 211 QLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQR 270 Q ++T + A +E +R +LA+ W+ Q + ++ EG Sbjct: 6 QANMDISTGHMILAYMEDHLRNRDRLAKE--------WQALCAYQAEPNTCATAQGEG-- 55 Query: 271 QENKNKNRYKNILPFDHTRVVLH-DGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIA 329 N KNR+ + LP+DH R+ L + P+ SDYINA+ I+ + +YIA Sbjct: 56 --NIKKNRHPDFLPYDHARIKLKVESSPSR--SDYINASPII-------EHDPRMPAYIA 104 Query: 330 TQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVK 389 TQG L +T+ DFW+MV++ VIVM T VE G +C +YWPDE A Y V V V Sbjct: 105 TQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGA-SLYHVYEVNLVS 163 Query: 390 ESA-AHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQES 448 E D+ +R L V Q RT+ Q+HF +WP G P+ +LDF +V+ Sbjct: 164 EHIWCEDFLVRSFYLKNV-QTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRG 222 Query: 449 IMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTE 508 + P++VHCS G GRTGT+I+ID++++ + KGV +ID+ T++ VR QR G+V+++ Sbjct: 223 --RSCPIIVHCSDGAGRTGTYILIDMVLNRM-AKGVK-EIDIAATLEHVRDQRPGLVRSK 278 Query: 509 AQYRFIYMAVQHYIETLQRRIEE 531 Q+ F AV + + + + + Sbjct: 279 DQFEFALTAVAEEVNAILKALPQ 301 >1ZC0-A nrPDB Length = 309 Score = 167 bits (422), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 98/249 (39%), Positives = 136/249 (54%), Gaps = 17/249 (6%) Query: 273 NKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQG 332 + +K+RYK ILP +RV L E DYINAN I + + K +K YIATQG Sbjct: 68 HASKDRYKTILPNPQSRVCLGRAQSQED-GDYINANYI------RGYDGK-EKVYIATQG 119 Query: 333 CLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESA 392 + NTV+DFW MV+QE +IVM T ++ GK KCV YWP E + YG ++R Sbjct: 120 PMPNTVSDFWEMVWQEEVSLIVMLT-QLREGKEKCVHYWPTEE--ETYGPFQIRIQDMKE 176 Query: 393 AHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDA 452 +YT+R+L + R+V F WPDH P G +L + EV E+ Sbjct: 177 CPEYTVRQLTIQY---QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHP 233 Query: 453 GPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYR 512 GP+VVHCSAGIGRTG FI I ++ +G ++D+ + +R R GM+QT QY+ Sbjct: 234 GPIVVHCSAGIGRTGCFIATRIGCQQLKARG---EVDILGIVCQLRLDRGGMIQTAEQYQ 290 Query: 513 FIYMAVQHY 521 F++ + Y Sbjct: 291 FLHHTLALY 299 >4GE6-A nrPDB Length = 314 Score = 165 bits (417), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 105/294 (35%), Positives = 160/294 (54%), Gaps = 31/294 (10%) Query: 244 KQGFWEEFETLQQQECKLLY--SRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPV 301 KQG +EE+E ++++ + S G N KNRY ++ D TRV L + Sbjct: 25 KQGIYEEYEDIRRENPVGTFHCSMSPG----NLEKNRYGDVPCLDQTRVKLTKRSGHTQ- 79 Query: 302 SDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVE 361 +DYINA+ + + K K +YI TQG L+NT DFW MV+++ VIVMTT+ E Sbjct: 80 TDYINASFM--------DGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEE 131 Query: 362 RGKSKCVKYWPDEYALK-EYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF 420 G+ KC +YWP E + +G + V N+ + Y L++ + +R V + F Sbjct: 132 GGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNT-EERQKRQVTHFQF 190 Query: 421 RTWPDHGVPSDPGGVLDFLEEVHHKQE-SIMDAG----------PVVVHCSAGIGRTGTF 469 +WPD+GVPS ++DFL V ++Q ++ + G P+VVHCSAGIGRTGTF Sbjct: 191 LSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTF 250 Query: 470 IVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE 523 +DI + + E G ++V +T+ +R+QR+ +QT QY F Y A+ + E Sbjct: 251 CSLDICLAQLEELGT---LNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAE 301 >4IKC-A nrPDB Length = 281 Score = 161 bits (407), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 99/273 (36%), Positives = 150/273 (54%), Gaps = 20/273 (7%) Query: 247 FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYIN 306 F EEF L + L S + N+ KNR+ NI P+++ RV L D + P SDYIN Sbjct: 24 FQEEFSELPKFLQDL--SSTDADLPWNRAKNRFPNIKPYNNNRVKL-IADASVPGSDYIN 80 Query: 307 ANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSK 366 A+ I C N +IATQG L TV DFWRMV++ ++ +VM T+ E+G+ + Sbjct: 81 ASYISGYL---CPNE-----FIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIR 132 Query: 367 CVKYWP-DEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPD 425 C +YWP D + +G + + + E D+T+R+LK+ + G T R Q +F WP+ Sbjct: 133 CHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHGDCMTVR---QCNFTAWPE 189 Query: 426 HGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVD 485 HGVP + ++ F++ V + D P++VH SAG+GRTG FI +D L I + Sbjct: 190 HGVPENSAPLIHFVKLV--RASRAHDTTPMIVHSSAGVGRTGVFIALDHLTQHINDHDF- 246 Query: 486 CDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 +D+ + +RS+R MVQ AQY F++ + Sbjct: 247 --VDIYGLVAELRSERMCMVQNLAQYIFLHQCI 277 >6D3F-A nrPDB Length = 279 Score = 161 bits (407), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 96/284 (33%), Positives = 155/284 (54%), Gaps = 19/284 (6%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYI 305 G EEF L + + + G N K R I+P+D RV+L E +DYI Sbjct: 4 GLEEEFRKLTNVRI-MKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQE-YTDYI 61 Query: 306 NANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKS 365 NA+ I + + K +IATQG L +TV DFWRM+++ S IVM T+ ER + Sbjct: 62 NASFI--------DGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQD 113 Query: 366 KCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLS----KVGQGNTERTVWQYHFR 421 KC +YWP E ++ +G + + ++ + ++R+ ++ + Q R V Q+HF Sbjct: 114 KCYQYWPTEGSVT-HGEITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFH 172 Query: 422 TWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIRE 481 WP+ G+P++ G++D + V +Q+ + P+ VHCSAG GRTGTFI + +++ ++ Sbjct: 173 GWPEIGIPAEGKGMIDLIAAVQKQQQQTGNH-PITVHCSAGAGRTGTFIALSNILERVKA 231 Query: 482 KGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETL 525 +G+ +DV + ++ +R QR MVQT QY F Y VQ +I+ Sbjct: 232 EGL---LDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIF 272 >2BZL-A nrPDB Length = 325 Score = 160 bits (404), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 103/326 (31%), Positives = 173/326 (53%), Gaps = 35/326 (10%) Query: 210 LQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGF-WEEFETLQQQECKLLYSRKEG 268 L + ++ TR+ ++ R R L K K+++G + E+E + +++ ++S Sbjct: 18 LYFQSMVDATRV---PMDERFRTLKK------KLEEGMVFTEYEQIPKKKANGIFS--TA 66 Query: 269 QRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYI 328 EN ++R + ++P++ RV L N + YINA+ I K + YI Sbjct: 67 ALPENAERSRIREVVPYEENRVELIPTKENN--TGYINASHI------KVVVGGAEWHYI 118 Query: 329 ATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWP---DEYALKEYGVMRV 385 ATQG L +T +DFW+MV+++ VI M T E E G++K +YWP +++ YG +V Sbjct: 119 ATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKV 178 Query: 386 RNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVH-- 443 + + Y LK+ + G ERTVW + WPDHG P D G L +LEE+ Sbjct: 179 TTKFRTDSVCYATTGLKVKHLLSGQ-ERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSV 237 Query: 444 HKQESIMDAG------PVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMV 497 + + M G P+VVHCSAG+GRTG I+ +++I + + ++VP ++++ Sbjct: 238 RRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEH---NEKVEVPMMLRLL 294 Query: 498 RSQRSGMVQTEAQYRFIYMAVQHYIE 523 R QR M+QT AQY+F+Y + +++ Sbjct: 295 REQRMFMIQTIAQYKFVYQVLIQFLQ 320 >4RHG-A nrPDB Length = 306 Score = 160 bits (404), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 102/297 (34%), Positives = 160/297 (53%), Gaps = 24/297 (8%) Query: 222 NAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKN 281 NA +E + +L K E+ + Q FE L +++ L + + +N +KNRYK+ Sbjct: 23 NADTLEGSMAQLKKGLESGTVLIQ-----FEQLYRKKPGLAITF--AKLPQNLDKNRYKD 75 Query: 282 ILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDF 341 +LP+D TRV+L + DYINA+ + E N K YIATQG L +T F Sbjct: 76 VLPYDTTRVLLQGNE------DYINASYV--NMEIPAANLVNK--YIATQGPLPHTCAQF 125 Query: 342 WRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLREL 401 W++V+ + +IVM T ERG++KC +YWPD + +G ++ E Y RE+ Sbjct: 126 WQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREM 185 Query: 402 KLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSA 461 ++ G E TV + WP+HGVP D DFLE V++ + +D+ PV+VH SA Sbjct: 186 LVTNTQTGE-EHTVTHLQYVAWPEHGVPDDSS---DFLEFVNYVRSLRVDSEPVLVHSSA 241 Query: 462 GIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 GIGRTG + ++ + + +D+ ++ +R QR+ MVQT +QY+F+ A+ Sbjct: 242 GIGRTGVLVTMETAMCLTERNLPIYPLDI---VRKMRDQRAMMVQTSSQYKFVCEAI 295 >4AZ1-A nrPDB Length = 302 Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 86/287 (29%), Positives = 133/287 (46%), Gaps = 37/287 (12%) Query: 250 EFETLQQQECKLLYSRKEGQRQ-------ENKNKNRYKNILPFDHTRVVLHDGDPNEPVS 302 ++E +Q++ LL R+E R +N++KNRY +IL + T P Sbjct: 17 QYERVQREFSLLL--RQEDPRSISFATSLKNRHKNRYLDILANEATLYPQVTDAPGASTP 74 Query: 303 DYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVER 362 YIN N+I + K ++A Q + + DF M++++ +++M TK E Sbjct: 75 YYINGNLIDLDLPHK---------FVACQAPVVQGIPDFLAMLYEKKISLVIMVTKLEEG 125 Query: 363 GKSKCVKYWPDEYALKEYGVMRVR-----NVKESAAHDYTLR-ELKLSK---VGQGNTE- 412 G K +YWP+E + G + V + E Y + ELK+++ + Q E Sbjct: 126 GFVKADRYWPEE---RGSGSIAVSGNCGLTISEDPGKAYEVEDELKITRRYLILQRADEP 182 Query: 413 -RTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIV 471 Q + WPDHG+P + L V + ++ PVVVHCSAGIGRTGT I Sbjct: 183 PHKFTQVQYTGWPDHGIPQSATSLEALLTNVKNSPTTV----PVVVHCSAGIGRTGTLIG 238 Query: 472 IDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 + + E+G D V + +R QR GMVQ QY IY+ + Sbjct: 239 AYAALTHL-ERGTLTDTTVYDVVSAMRRQRFGMVQRMEQYFVIYLTL 284 >3M4U-A nrPDB Length = 306 Score = 100 bits (250), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 119/259 (45%), Gaps = 27/259 (10%) Query: 272 ENKNKNRYKNILPFDHTRV--VLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIA 329 +N++KNRY +IL + T VL YIN N+I + +++A Sbjct: 44 KNRHKNRYLDILANEETIYPPVLKAVGAQPGRYPYINGNLIDLDL---------PHTFVA 94 Query: 330 TQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDE----YALKEYGVMRV 385 Q + V DF + ++ ++VM TK E G K +YWP+E + E G + Sbjct: 95 CQAPVPQGVPDFLETLSEKKVDLVVMLTKLREGGVLKAERYWPEEEEDSLSFPESGHDAI 154 Query: 386 RNVKESAAHDYTLRELKLSKVG-----QGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLE 440 + +++ A EL + + G V Q + WPDHGVP + L Sbjct: 155 KVTRDAEASYEVDAELDIVRRPLVIHVPGKPMHRVLQVQYVGWPDHGVPESAASFDELLS 214 Query: 441 EVHHKQESIMDAGPVVVHCSAGIGRTGTFI-VIDILIDIIREKGVDCDIDVPKTIQMVRS 499 + ++ + P++VHCSAGIGRTGT I L+ I E+G+ D V + ++ Sbjct: 215 VI----KNCVTTSPILVHCSAGIGRTGTLIGAYAALLHI--ERGILTDSTVYSIVAAMKQ 268 Query: 500 QRSGMVQTEAQYRFIYMAV 518 +R GMVQ QY IYM V Sbjct: 269 KRFGMVQRLEQYAVIYMTV 287 >2PLE-A nrPDB Length = 105 Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 8/101 (7%) Query: 3 SRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDY 62 S+ W+H ++T +AE++L+ DG+FL R ++ P + +S R G + H ++Q G Sbjct: 8 SKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCRVQQEGQT 66 Query: 63 YDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 L G +F +L +L+ YY +H K K L+YP+N Sbjct: 67 VML-GNSEFDSLVDLISYYEKHPLYRKMK------LRYPIN 100 Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 16/109 (14%) Query: 109 SERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVT 168 S+ W+H L+ +AE +L + G+FLVR+ ++ P + +S R + K+ Sbjct: 8 SKEWYHASLTRAQAEHMLMRVPRDGAFLVRK-RNEPNSYAISFR----------AEGKIK 56 Query: 169 HVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLN 217 H ++ QE + + G FDSL DL+ +Y+K+P+ ++L+ P+N Sbjct: 57 HCRVQ-QEGQTVMLGNSEFDSLVDLISYYEKHPLYRK----MKLRYPIN 100 >4XEY-B nrPDB Length = 408 Score = 58.2 bits (139), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 37/97 (38%), Positives = 53/97 (54%), Gaps = 8/97 (8%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 W+H ++ AE LL+ G++GSFL R S+S+PG ++S+R G V H +I D Sbjct: 12 WYHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 70 Query: 66 YGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 E +F TLAELV HH + +G + L YP Sbjct: 71 VSSESRFNTLAELVH----HHSTV--ADGLITTLHYP 101 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 37/105 (35%), Positives = 54/105 (51%), Gaps = 14/105 (13%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 W+HG +S AE LL+ G +GSFLVRES+S PG +S+R + +V H Sbjct: 12 WYHGPVSRNAAEYLLS-SGINGSFLVRESESSPGQRSISLRY----------EGRVYHYR 60 Query: 172 IR-CQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQP 215 I + K V RF++L +LV H+ + + + L T L P Sbjct: 61 INTASDGKLYVSSESRFNTLAELVHHH--STVADGLITTLHYPAP 103 >2FO0-A nrPDB Length = 495 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 37/97 (38%), Positives = 53/97 (54%), Gaps = 8/97 (8%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 W+H ++ AE LL+ G++GSFL R S+S+PG ++S+R G V H +I D Sbjct: 104 WYHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 162 Query: 66 YGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 E +F TLAELV HH + + G + L YP Sbjct: 163 VSSESRFNTLAELVH----HHSTVAD--GLITTLHYP 193 Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 56/194 (28%), Positives = 82/194 (42%), Gaps = 34/194 (17%) Query: 28 SFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD-YYDLYGGEKFATLAELVQYYMEHHG 86 + LA PS+++P F V +GD + GEK L H+G Sbjct: 30 NLLAGPSENDPNLF---------VALYDFVASGDNTLSITKGEKLRVLG------YNHNG 74 Query: 87 QLKEKNGDVIELKYPLNCADPTSE----RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQS 142 + E + P N P + W+HG +S AE LL+ G +GSFLVRES+S Sbjct: 75 EWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLS-SGINGSFLVRESES 133 Query: 143 HPGDFVLSVRTGDDKGESNDGKSKVTHVMIR-CQELKYDVGGGERFDSLTDLVEHYKKNP 201 PG +S+R + +V H I + K V RF++L +LV H+ Sbjct: 134 SPGQRSISLRY----------EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST-- 181 Query: 202 MVETLGTVLQLKQP 215 + + L T L P Sbjct: 182 VADGLITTLHYPAP 195 >2AUG-A nrPDB Length = 126 Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 6/95 (6%) Query: 3 SRRWFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61 S+ WFH I+ EA+ L++ +G VDG FL R S+SNP F LS+ + H +I D Sbjct: 25 SQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVED 84 Query: 62 YYDLY-----GGEKFATLAELVQYYMEHHGQLKEK 91 +++ G +F L +LV++Y + G L K Sbjct: 85 DGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCK 119 Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 36/98 (36%), Positives = 50/98 (51%), Gaps = 16/98 (16%) Query: 109 SERWFHGHLSGKEAEKLLTEKGK-HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKV 167 S+ WFH +S EA++L+ ++G G FLVR+SQS+P FVLS+ G K+ Sbjct: 25 SQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHG----------QKI 74 Query: 168 THVMIRCQELKYDV-----GGGERFDSLTDLVEHYKKN 200 H I E ++ G RF L LVE Y+ N Sbjct: 75 KHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLN 112 >2ABL-A nrPDB Length = 163 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 37/97 (38%), Positives = 53/97 (54%), Gaps = 8/97 (8%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 W+H ++ AE LL+ G++GSFL R S+S+PG ++S+R G V H +I D Sbjct: 72 WYHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 130 Query: 66 YGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 E +F TLAELV HH + + G + L YP Sbjct: 131 VSSESRFNTLAELVH----HHSTVAD--GLITTLHYP 161 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 40/116 (34%), Positives = 59/116 (50%), Gaps = 16/116 (13%) Query: 101 PLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGES 160 P+N + S W+HG +S AE LL+ G +GSFLVRES+S PG +S+R Sbjct: 63 PVNSLEKHS--WYHGPVSRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRY------- 112 Query: 161 NDGKSKVTHVMIR-CQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQP 215 + +V H I + K V RF++L +LV H+ + + + L T L P Sbjct: 113 ---EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHH--STVADGLITTLHYPAP 163 >6AMW-A nrPDB Length = 255 Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 37/97 (38%), Positives = 53/97 (54%), Gaps = 8/97 (8%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 W+H ++ AE LL+ G++GSFL R S+S+PG ++S+R G V H +I D Sbjct: 146 WYHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 204 Query: 66 YGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 E +F TLAELV HH + + G + L YP Sbjct: 205 VSSESRFNTLAELVH----HHSTVAD--GLITTLHYP 235 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 56/194 (28%), Positives = 82/194 (42%), Gaps = 34/194 (17%) Query: 28 SFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD-YYDLYGGEKFATLAELVQYYMEHHG 86 + LA PS+++P F V +GD + GEK L H+G Sbjct: 72 NLLAGPSENDPNLF---------VALYDFVASGDNTLSITKGEKLRVLG------YNHNG 116 Query: 87 QLKEKNGDVIELKYPLNCADPTSE----RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQS 142 + E + P N P + W+HG +S AE LL+ G +GSFLVRES+S Sbjct: 117 EWAEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLS-SGINGSFLVRESES 175 Query: 143 HPGDFVLSVRTGDDKGESNDGKSKVTHVMIR-CQELKYDVGGGERFDSLTDLVEHYKKNP 201 PG +S+R + +V H I + K V RF++L +LV H+ Sbjct: 176 SPGQRSISLRY----------EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST-- 223 Query: 202 MVETLGTVLQLKQP 215 + + L T L P Sbjct: 224 VADGLITTLHYPAP 237 >1A81-A nrPDB Length = 254 Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 65/247 (26%), Positives = 100/247 (40%), Gaps = 72/247 (29%) Query: 6 WFHPNITGVEAENLLLTRGV-DGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQN-TGDYY 63 +F NIT EAE+ L+ G+ DG +L R S++ G F LSV H I+ Y Sbjct: 7 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTY 66 Query: 64 DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN-------------------- 103 + GG A+ A+L Y+ + E +G V LK P N Sbjct: 67 AIAGGRTHASPADLCHYHSQ------ESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLI 120 Query: 104 --------------------CADPTSER-----------WFHGHLSGKEAEKLLTEKGK- 131 P E+ WFHG +S +E+E+++ K Sbjct: 121 REYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQIVLIGSKT 180 Query: 132 HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI-RCQELKYDVGGGERFDSL 190 +G FL+R ++ + G + L + + KV H I + + K + G++FD+L Sbjct: 181 NGKFLIR-ARDNNGSYALCLLH----------EGKVLHYRIDKDKTGKLSIPEGKKFDTL 229 Query: 191 TDLVEHY 197 LVEHY Sbjct: 230 WQLVEHY 236 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 35/109 (32%), Positives = 54/109 (49%), Gaps = 18/109 (16%) Query: 112 WFHGHLSGKEAEKLLTEKG-KHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHV 170 +F G+++ +EAE L + G G +L+R+S+++ G F LSV G K H Sbjct: 7 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHG----------RKAHHY 56 Query: 171 MIRCQELK--YDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLN 217 I +EL Y + GG S DL ++ + E+ G V LK+P N Sbjct: 57 TIE-RELNGTYAIAGGRTHASPADLCHYHSQ----ESDGLVCLLKKPFN 100 >4FL3-A nrPDB Length = 635 Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 67/247 (27%), Positives = 100/247 (40%), Gaps = 72/247 (29%) Query: 6 WFHPNITGVEAENLLLTRGV-DGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQ-NTGDYY 63 +F NIT EAE+ L+ G+ DG +L R S++ G F LSV H I+ Y Sbjct: 15 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTY 74 Query: 64 DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN-------------------- 103 + GG A+ A+L Y H Q E +G V LK P N Sbjct: 75 AIAGGRTHASPADLCHY----HSQ--ESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLI 128 Query: 104 --------------------CADPTSER-----------WFHGHLSGKEAEKLLTEKGK- 131 P E+ WFHG +S +E+E+++ K Sbjct: 129 REYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQIVLIGSKT 188 Query: 132 HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI-RCQELKYDVGGGERFDSL 190 +G FL+R ++ + G + L + + KV H I + + K + G++FD+L Sbjct: 189 NGKFLIR-ARDNNGSYALCLLH----------EGKVLHYRIDKDKTGKLSIPEGKKFDTL 237 Query: 191 TDLVEHY 197 LVEHY Sbjct: 238 WQLVEHY 244 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 35/109 (32%), Positives = 54/109 (49%), Gaps = 18/109 (16%) Query: 112 WFHGHLSGKEAEKLLTEKG-KHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHV 170 +F G+++ +EAE L + G G +L+R+S+++ G F LSV G K H Sbjct: 15 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHG----------RKAHHY 64 Query: 171 MIRCQELK--YDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLN 217 I +EL Y + GG S DL ++ + E+ G V LK+P N Sbjct: 65 TIE-RELNGTYAIAGGRTHASPADLCHYHSQ----ESDGLVCLLKKPFN 108 >3T04-A nrPDB Length = 123 Score = 56.2 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 37/97 (38%), Positives = 53/97 (54%), Gaps = 8/97 (8%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 W+H ++ AE LL+ G++GSFL R S+S+PG ++S+R G V H +I D Sbjct: 18 WYHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 76 Query: 66 YGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 E +F TLAELV HH + + G + L YP Sbjct: 77 VSSESRFNTLAELVH----HHSTVAD--GLITTLHYP 107 Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 40/116 (34%), Positives = 59/116 (50%), Gaps = 16/116 (13%) Query: 101 PLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGES 160 P+N + S W+HG +S AE LL+ G +GSFLVRES+S PG +S+R Sbjct: 9 PVNSLEKHS--WYHGPVSRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRY------- 58 Query: 161 NDGKSKVTHVMIR-CQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQP 215 + +V H I + K V RF++L +LV H+ + + + L T L P Sbjct: 59 ---EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHH--STVADGLITTLHYPAP 109 >1GRI-A nrPDB Length = 217 Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 32/81 (39%), Positives = 42/81 (51%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 M WF I +AE +L + DG+FL R S+S PGDF+LSV+ V H K+ G Sbjct: 55 MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDG 114 Query: 61 DYYDLYGGEKFATLAELVQYY 81 KF +L ELV Y+ Sbjct: 115 AGKYFLWVVKFNSLNELVDYH 135 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 37/116 (31%), Positives = 64/116 (55%), Gaps = 17/116 (14%) Query: 84 HHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSH 143 + +L K+G + P N + WF G + +AE++L+++ G+FL+RES+S Sbjct: 37 YKAELNGKDGFI-----PKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESA 91 Query: 144 PGDFVLSVRTGDDKGESNDGKSKVTHV-MIRCQELKYDVGGGERFDSLTDLVEHYK 198 PGDF LSV+ G+D V H ++R KY + +F+SL +LV++++ Sbjct: 92 PGDFSLSVKFGND----------VQHFKVLRDGAGKYFL-WVVKFNSLNELVDYHR 136 >1K9A-A nrPDB Length = 450 Score = 52.8 bits (125), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 45/158 (28%), Positives = 68/158 (43%), Gaps = 34/158 (21%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 WFHG ++ ++AE+LL + G FLVRES ++PGD+ L V + KV H Sbjct: 82 WFHGKITREQAERLLYPP-ETGLFLVRESTNYPGDYTLCVSC----------EGKVEHYR 130 Query: 172 IRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVR 231 I K + F++L LVEHY + G +L +P Sbjct: 131 IMYHASKLSIDEEVYFENLMQLVEHYT----TDADGLCTRLIKP---------------- 170 Query: 232 ELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQ 269 K+ E T + F+ L +E KLL + +G+ Sbjct: 171 ---KVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGE 205 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 29/76 (38%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 WFH IT +AE LL G FL R S + PGD+TL V G V H +I + Sbjct: 82 WFHGKITREQAERLLYPPET-GLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSI 140 Query: 66 YGGEKFATLAELVQYY 81 F L +LV++Y Sbjct: 141 DEEVYFENLMQLVEHY 156 >2LQW-A nrPDB Length = 303 Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 32/87 (36%), Positives = 47/87 (54%), Gaps = 11/87 (12%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 W+ G +S +EA+ L + +HG FLVR+S + PGD+VLSV S+V+H + Sbjct: 14 WYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSE----------NSRVSHYI 62 Query: 172 IRCQELKYDVGGGERFDSLTDLVEHYK 198 I + G + FD L L+E YK Sbjct: 63 INSLPNRRFKIGDQEFDHLPALLEFYK 89 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 32/59 (54%) Query: 27 GSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHH 85 G FL R S + PGD+ LSV N V+H I + + G ++F L L+++Y H+ Sbjct: 34 GMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHY 92 >6F3F-A nrPDB Length = 455 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 42/127 (33%), Positives = 62/127 (48%), Gaps = 21/127 (16%) Query: 101 PLNCADPT----SERWFHGHLSGKEAEKLL-TEKGKHGSFLVRESQSHPGDFVLSVRTGD 155 P N P+ +E W+ G ++ +E+E+LL + G+FLVRES++ G + LSV D Sbjct: 55 PSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFD 114 Query: 156 DKGESNDGKSKVTHVMIRCQELKYDVGGG-----ERFDSLTDLVEHYKKNP--MVETLGT 208 + N V H IR K D GG +F+SL LV +Y K+ + L T Sbjct: 115 NAKGLN-----VKHYKIR----KLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTT 165 Query: 209 VLQLKQP 215 V +P Sbjct: 166 VCPTSKP 172 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 9/96 (9%) Query: 1 MTSRRWFHPNITGVEAENLLL-TRGVDGSFLARPSKSNPGDFTLSVR-----RNGAVTHI 54 + + W+ IT E+E LLL G+FL R S++ G + LSV + V H Sbjct: 65 IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHY 124 Query: 55 KIQ--NTGDYYDLYGGEKFATLAELVQYYMEHHGQL 88 KI+ ++G +Y + +F +L +LV YY +H L Sbjct: 125 KIRKLDSGGFY-ITSRTQFNSLQQLVAYYSKHADGL 159 >2H8H-A nrPDB Length = 535 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 42/127 (33%), Positives = 62/127 (48%), Gaps = 21/127 (16%) Query: 101 PLNCADPT----SERWFHGHLSGKEAEKLL-TEKGKHGSFLVRESQSHPGDFVLSVRTGD 155 P N P+ +E W+ G ++ +E+E+LL + G+FLVRES++ G + LSV D Sbjct: 135 PSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFD 194 Query: 156 DKGESNDGKSKVTHVMIRCQELKYDVGG-----GERFDSLTDLVEHYKKNP--MVETLGT 208 + N V H IR K D GG +F+SL LV +Y K+ + L T Sbjct: 195 NAKGLN-----VKHYKIR----KLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTT 245 Query: 209 VLQLKQP 215 V +P Sbjct: 246 VCPTSKP 252 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 9/92 (9%) Query: 1 MTSRRWFHPNITGVEAENLLL-TRGVDGSFLARPSKSNPGDFTLSVR-----RNGAVTHI 54 + + W+ IT E+E LLL G+FL R S++ G + LSV + V H Sbjct: 145 IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHY 204 Query: 55 KIQ--NTGDYYDLYGGEKFATLAELVQYYMEH 84 KI+ ++G +Y + +F +L +LV YY +H Sbjct: 205 KIRKLDSGGFY-ITSRTQFNSLQQLVAYYSKH 235 >2EOB-A nrPDB Length = 124 Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 7/100 (7%) Query: 3 SRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDY 62 S+ W++ ++ EAE++L+ DG+FL R + + ++ R G V H +I G + Sbjct: 18 SKPWYYDRLSRGEAEDMLMRIPRDGAFLIR-KREGTDSYAITFRARGKVKHCRINRDGRH 76 Query: 63 YDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 102 + L F +L ELV YY +H K + L+YP+ Sbjct: 77 FVLGTSAYFESLVELVSYYEKHALYRK------MRLRYPV 110 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 11/94 (11%) Query: 109 SERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVT 168 S+ W++ LS EAE +L + G+FL+R+ + + ++ R + KV Sbjct: 18 SKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREG-TDSYAITFR----------ARGKVK 66 Query: 169 HVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPM 202 H I + +G F+SL +LV +Y+K+ + Sbjct: 67 HCRINRDGRHFVLGTSAYFESLVELVSYYEKHAL 100 >5U06-A nrPDB Length = 120 Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 37/105 (35%), Positives = 56/105 (53%), Gaps = 16/105 (15%) Query: 102 LNCADPTSERWFHGHLSGKEAEKLLTEKG-KHGSFLVRESQSHPGDFVLSVRTGDDKGES 160 L+ A ++ WFHG +S +E+++L+ ++G G FLVRESQ +P FVLS+ Sbjct: 9 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCH------- 61 Query: 161 NDGKSKVTHVMIRCQE----LKYDVGGGE-RFDSLTDLVEHYKKN 200 KV H +I E L + + G+ RF L LVE ++ N Sbjct: 62 ---LQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLN 103 Score = 46.2 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 6/92 (6%) Query: 3 SRRWFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61 ++ WFH I+ E++ L+ +G VDG FL R S+ NP F LS+ V H I + + Sbjct: 16 TQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEE 75 Query: 62 YYDLY-----GGEKFATLAELVQYYMEHHGQL 88 LY G +F L +LV+++ + G L Sbjct: 76 EGRLYFSMDDGQTRFTDLLQLVEFHQLNRGIL 107 >1MIL-A nrPDB Length = 104 Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 37/108 (34%), Positives = 58/108 (53%), Gaps = 15/108 (13%) Query: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTH 169 E WFHG LS +EAE LL +G FLVRES + PG +VL TG G+ Sbjct: 7 EPWFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVL---TGLQSGQPKHLLLVDPE 60 Query: 170 VMIRCQELKYDVGGGERFDSLTDLVEHYKKNPM-VETLGTVLQLKQPL 216 ++R ++ RF+S++ L+ ++ N + + + G+ L L+QP+ Sbjct: 61 GVVRTKD--------HRFESVSHLISYHMDNHLPIISAGSELCLQQPV 100 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 46/86 (53%), Gaps = 16/86 (18%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQN------T 59 WFH ++ EAE LL ++G FL R S + PG + L+ ++G H+ + + T Sbjct: 9 WFHGKLSRREAEALL---QLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRT 65 Query: 60 GDYYDLYGGEKFATLAELVQYYMEHH 85 D+ +F +++ L+ Y+M++H Sbjct: 66 KDH-------RFESVSHLISYHMDNH 84 >2EYZ-A nrPDB Length = 304 Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 36/104 (34%), Positives = 49/104 (47%), Gaps = 28/104 (26%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 W+ G LS +EA LL + +HG FLVR+S + PGD+VLSV S+V+H + Sbjct: 13 WYWGRLSRQEAVALLQGQ-RHGVFLVRDSSTSPGDYVLSVSE----------NSRVSHYI 61 Query: 172 IRCQELKYDVG-----------------GGERFDSLTDLVEHYK 198 I + V G + FDSL L+E YK Sbjct: 62 INSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYK 105 Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust. Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKI 56 W+ ++ EA LL + G FL R S ++PGD+ LSV N V+H I Sbjct: 13 WYWGRLSRQEAVALLQGQ-RHGVFLVRDSSTSPGDYVLSVSENSRVSHYII 62 >2KK6-A nrPDB Length = 116 Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 10/113 (8%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + + W+H I +EA+ LL +G FL R S PG++ LSV +G H IQ Sbjct: 14 LAEQDWYHGAIPRIEAQELLKKQG---DFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVD 70 Query: 61 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWF 113 + Y + G F+ + +L+ ++ + +K+G V+ LN P ++W Sbjct: 71 NMYR-FEGTGFSNIPQLIDHHYTTKQVITKKSGVVL-----LNPI-PKDKKWI 116 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 36/111 (32%), Positives = 58/111 (52%), Gaps = 15/111 (13%) Query: 107 PTSER-WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS 165 P +E+ W+HG + EA++LL K G FLVRES PG++VLSV + DG+ Sbjct: 13 PLAEQDWYHGAIPRIEAQELLK---KQGDFLVRESHGKPGEYVLSVYS--------DGQR 61 Query: 166 KVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPL 216 + H +I+ + Y G F ++ L++H+ V T + + L P+ Sbjct: 62 R--HFIIQYVDNMYRF-EGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPI 109 >1AD5-A nrPDB Length = 438 Score = 48.9 bits (115), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 11/132 (8%) Query: 109 SERWFHGHLSGKEAEKLLTEKGKH-GSFLVRESQSHPGDFVLSVRTGDDK-GESNDGKSK 166 +E WF +S K+AE+ L G GSF++R+S++ G + LSVR D + G++ Sbjct: 63 TEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDT------ 116 Query: 167 VTHVMIRCQEL-KYDVGGGERFDSLTDLVEHYKK--NPMVETLGTVLQLKQPLNTTRINA 223 V H IR + + + F +L +LV+HYKK + + + L +P +A Sbjct: 117 VKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEKDA 176 Query: 224 AEIESRVRELSK 235 EI +L K Sbjct: 177 WEIPRESLKLEK 188 Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 35/99 (35%), Positives = 54/99 (54%), Gaps = 9/99 (9%) Query: 1 MTSRRWFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVR----RNG-AVTHI 54 + + WF I+ +AE LL G + GSF+ R S++ G ++LSVR R G V H Sbjct: 61 LETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHY 120 Query: 55 KIQ--NTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEK 91 KI+ + G +Y + F+TL ELV +Y + + L +K Sbjct: 121 KIRTLDNGGFY-ISPRSTFSTLQELVDHYKKGNDGLCQK 158 >2EKX-A nrPDB Length = 110 Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 10/107 (9%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 WF G++S ++E+LL +KGK G+F+VR S S G + +S+ + ND K V H Sbjct: 13 WFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQVGMYTVSLFS----KAVNDKKGTVKHYH 67 Query: 172 IRCQ-ELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLN 217 + E K + FDS+ L+ +++ N + G + +L+ P++ Sbjct: 68 VHTNAENKLYLAENYCFDSIPKLIHYHQHN----SAGMITRLRHPVS 110 Score = 37.0 bits (84), Expect = 0.022, Method: Compositional matrix adjust. Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 16/106 (15%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSV------RRNGAVTHIKIQNT 59 WF NI+ ++E LL +G +G+F+ R S S G +T+S+ + G V H + Sbjct: 13 WFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQVGMYTVSLFSKAVNDKKGTVKHYHVHTN 71 Query: 60 GDYYDLYGGEK--FATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 + LY E F ++ +L+ Y+ G + L++P++ Sbjct: 72 AE-NKLYLAENYCFDSIPKLIHYHQH------NSAGMITRLRHPVS 110 >2LCT-A nrPDB Length = 107 Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 W+ + AE++L R DG+FL R + +F +S++ N V HIKI Y + Sbjct: 11 WYAGPMERAGAESILANRS-DGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRI 69 Query: 66 YGGEKFATLAELVQYYMEH 84 + F L ELV++Y ++ Sbjct: 70 TEKKAFRGLTELVEFYQQN 88 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 14/110 (12%) Query: 106 DPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS 165 D + W+ G + AE +L + G+FLVR+ +F +S++ Sbjct: 5 DLSVHLWYAGPMERAGAESILANRSD-GTFLVRQRVKDAAEFAISIKYN----------V 53 Query: 166 KVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPM---VETLGTVLQL 212 +V H+ I E Y + + F LT+LVE Y++N + ++L T LQ Sbjct: 54 EVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQF 103 >2CRH-A nrPDB Length = 138 Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 W+ + AE++L R DG+FL R + +F +S++ N V HIKI Y + Sbjct: 28 WYAGPMERAGAESILANRS-DGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRI 86 Query: 66 YGGEKFATLAELVQYYMEH 84 + F L ELV++Y ++ Sbjct: 87 TEKKAFRGLTELVEFYQQN 105 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 16/109 (14%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 W+ G + AE +L + G+FLVR+ +F +S++ + V H+ Sbjct: 28 WYAGPMERAGAESILANR-SDGTFLVRQRVKDAAEFAISIKYNVE----------VKHIK 76 Query: 172 IRCQELKYDVGGGERFDSLTDLVEHYKKNPM---VETLGTVLQ--LKQP 215 I E Y + + F LT+LVE Y++N + ++L T LQ K+P Sbjct: 77 IMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEP 125 >4XI2-A nrPDB Length = 446 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 31/115 (26%), Positives = 61/115 (53%), Gaps = 14/115 (12%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSV---RTGDDKGESNDGKSKVT 168 W+ H++ +AE+LL ++GK G F+VR+S S G + +SV TG+ +G Sbjct: 68 WYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGEPQGVIRH------ 120 Query: 169 HVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINA 223 +V+ + +Y + F ++ +L+ +++ N + G + +LK P++ NA Sbjct: 121 YVVCSTPQSQYYLAEKHLFSTIPELINYHQHN----SAGLISRLKYPVSKQNKNA 171 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 16/106 (15%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSV------RRNGAVTHIKIQNT 59 W+ ++T +AE LL G +G F+ R S S G +T+SV G + H + +T Sbjct: 68 WYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGEPQGVIRHYVVCST 126 Query: 60 --GDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 YY L F+T+ EL+ Y+ + G + LKYP++ Sbjct: 127 PQSQYY-LAEKHLFSTIPELINYHQHNSA------GLISRLKYPVS 165 >2HDV-A nrPDB Length = 111 Score = 46.6 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 24/99 (24%) Query: 112 WFHGHLSGKEAEKLLTE--KGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTH 169 WFHG LS +A +L+ E G HG FLVR+S++ G+ VL+ + GK+K Sbjct: 11 WFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRRGECVLTF--------NFQGKAKHLR 62 Query: 170 VMI------RCQELKYDVGGGERFDSLTDLVEHYKKNPM 202 + + R Q L F S+ D++EH++ +P+ Sbjct: 63 LSLNAAGQCRVQHL--------HFQSIFDMLEHFRVHPI 93 >1NRV-A nrPDB Length = 105 Score = 46.2 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 30/92 (32%), Positives = 50/92 (54%), Gaps = 6/92 (6%) Query: 3 SRRWFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61 ++ WFH I+ E+ ++ +G VDG FL R S+SNP F L++ + + + +I D Sbjct: 4 TQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCED 63 Query: 62 ----YYDL-YGGEKFATLAELVQYYMEHHGQL 88 ++ L G KF+ L +LV +Y + G L Sbjct: 64 DGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVL 95 Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 18/44 (40%), Positives = 33/44 (75%), Gaps = 1/44 (2%) Query: 109 SERWFHGHLSGKEAEKLLTEKG-KHGSFLVRESQSHPGDFVLSV 151 ++ WFHG +S +E+ +++ ++G G FL+R+SQS+P FVL++ Sbjct: 4 TQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTL 47 >2OZO-A nrPDB Length = 613 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Query: 6 WFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVRRNGAVTHIKI-QNTGDYY 63 W+H ++T EAE L + DG FL RP K G + LS+ V H I Q+ Y Sbjct: 163 WYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQ-GTYALSLIYGKTVYHYLISQDKAGKY 221 Query: 64 DLYGGEKFATLAELVQY 80 + G KF TL +LV+Y Sbjct: 222 CIPEGTKFDTLWQLVEY 238 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 60/248 (24%), Positives = 92/248 (37%), Gaps = 72/248 (29%) Query: 6 WFHPNITGVEAENLLLTRGV-DGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQ-NTGDYY 63 +F+ +I+ EAE L G+ DG FL R + G + LS+ + H I+ Y Sbjct: 10 FFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTY 69 Query: 64 DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN-------------------- 103 + GG+ AEL ++Y ++ +G L+ P N Sbjct: 70 AIAGGKAHCGPAELCEFYS------RDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMV 123 Query: 104 -----------------------------CADPTSER--WFHGHLSGKEAE-KLLTEKGK 131 A ER W+H L+ +EAE KL + Sbjct: 124 RDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSGAQT 183 Query: 132 HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQEL-KYDVGGGERFDSL 190 G FL+R + G + LS+ G V H +I + KY + G +FD+L Sbjct: 184 DGKFLLRPRKEQ-GTYALSLIYG----------KTVYHYLISQDKAGKYCIPEGTKFDTL 232 Query: 191 TDLVEHYK 198 LVE+ K Sbjct: 233 WQLVEYLK 240 >3CXL-A nrPDB Length = 463 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 20/87 (22%) Query: 111 RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESN---DGKSKV 167 R FHG +S + A++LL GS+L+RESQ PG + L++R G DGK V Sbjct: 52 REFHGMISREAADQLLI--VAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFV 109 Query: 168 THVMIRCQELKYDVGGGERFDSLTDLV 194 G +RF+S+ DLV Sbjct: 110 ---------------GEKRFESIHDLV 121 Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 41/74 (55%), Gaps = 4/74 (5%) Query: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64 R FH I+ A+ LL+ +GS+L R S+ PG +TL++R + ++ G ++ Sbjct: 52 REFHGMISREAADQLLIV--AEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHF- 108 Query: 65 LYGGEKFATLAELV 78 G ++F ++ +LV Sbjct: 109 -VGEKRFESIHDLV 121 >1XA6-A nrPDB Length = 466 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 20/87 (22%) Query: 111 RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGES---NDGKSKV 167 R FHG +S ++A++LL G G++++RESQ PG + L++R G+ +DGK V Sbjct: 56 REFHGIISREQADELL--GGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFV 113 Query: 168 THVMIRCQELKYDVGGGERFDSLTDLV 194 G +RF+S+ DLV Sbjct: 114 ---------------GEKRFESIHDLV 125 Score = 38.5 bits (88), Expect = 0.008, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 44/74 (59%), Gaps = 4/74 (5%) Query: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64 R FH I+ +A+ LL GV+G+++ R S+ PG +TL++R + ++ + G ++ Sbjct: 56 REFHGIISREQADELL--GGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHF- 112 Query: 65 LYGGEKFATLAELV 78 G ++F ++ +LV Sbjct: 113 -VGEKRFESIHDLV 125 >4XZ1-A nrPDB Length = 262 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Query: 6 WFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVRRNGAVTHIKI-QNTGDYY 63 W+H ++T EAE L + DG FL RP K G + LS+ V H I Q+ Y Sbjct: 166 WYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQ-GTYALSLIYGKTVYHYLISQDKAGKY 224 Query: 64 DLYGGEKFATLAELVQY 80 + G KF TL +LV+Y Sbjct: 225 CIPEGTKFDTLWQLVEY 241 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 60/248 (24%), Positives = 92/248 (37%), Gaps = 72/248 (29%) Query: 6 WFHPNITGVEAENLLLTRGV-DGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQ-NTGDYY 63 +F+ +I+ EAE L G+ DG FL R + G + LS+ + H I+ Y Sbjct: 13 FFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTY 72 Query: 64 DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN-------------------- 103 + GG+ AEL ++Y ++ +G L+ P N Sbjct: 73 AIAGGKAHCGPAELCEFYS------RDPDGLPCNLRKPCNRPSGLEPQPGVFDSLRDAMV 126 Query: 104 -----------------------------CADPTSER--WFHGHLSGKEAE-KLLTEKGK 131 A ER W+H L+ +EAE KL + Sbjct: 127 RDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSGAQT 186 Query: 132 HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQEL-KYDVGGGERFDSL 190 G FL+R + G + LS+ G V H +I + KY + G +FD+L Sbjct: 187 DGKFLLRPRKEQ-GTYALSLIYG----------KTVYHYLISQDKAGKYCIPEGTKFDTL 235 Query: 191 TDLVEHYK 198 LVE+ K Sbjct: 236 WQLVEYLK 243 >4M4Z-A nrPDB Length = 170 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 7/93 (7%) Query: 109 SERWFHGHLSGKEAEKLLTEKGK-HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKV 167 S W + LS ++AE+LL G G+FL+RESQ+ G + LSVR + S D ++ Sbjct: 68 SHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRL--SRPASWD---RI 122 Query: 168 THVMIRCQELKY-DVGGGERFDSLTDLVEHYKK 199 H I C + + + F SL LV+HY + Sbjct: 123 RHYRIHCLDNGWLYISPRLTFPSLQALVDHYSE 155 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 9/89 (10%) Query: 3 SRRWFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVRRN-----GAVTHIKI 56 S W + ++ +AE LLL G G+FL R S++ G ++LSVR + + H +I Sbjct: 68 SHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRI 127 Query: 57 QNTGDYYDLYGGEK--FATLAELVQYYME 83 + + LY + F +L LV +Y E Sbjct: 128 HCLDNGW-LYISPRLTFPSLQALVDHYSE 155 >2CS0-A nrPDB Length = 119 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 29/80 (36%), Positives = 45/80 (56%), Gaps = 4/80 (5%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 WFH I+ +AENLL ++ + GSFL R S S+ G +TLS + + H ++ D + Sbjct: 18 WFHGAISREDAENLLESQPL-GSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFM 75 Query: 66 YGGEKFA--TLAELVQYYME 83 GEK A +L LV ++ + Sbjct: 76 IPGEKVAHTSLDALVTFHQQ 95 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 14/93 (15%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 WFHG +S ++AE LL E GSFL+R S SH G + LS + +S H M Sbjct: 18 WFHGAISREDAENLL-ESQPLGSFLIRVSHSHVG-YTLSYK----------AQSSCCHFM 65 Query: 172 IRCQELKYDVGGGERF--DSLTDLVEHYKKNPM 202 ++ + + GE+ SL LV +++ P+ Sbjct: 66 VKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPI 98 >1M27-A nrPDB Length = 104 Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 32/59 (54%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT 59 M + +H I+ E LLL G+DGS+L R S+S PG + L V +G + ++ T Sbjct: 1 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQT 59 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 18/39 (46%), Positives = 26/39 (66%) Query: 113 FHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSV 151 +HG +S + EKLL G GS+L+R+S+S PG + L V Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCV 45 >1KA6-A nrPDB Length = 128 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 32/59 (54%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT 59 M + +H I+ E LLL G+DGS+L R S+S PG + L V +G + ++ T Sbjct: 1 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQT 59 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 18/39 (46%), Positives = 26/39 (66%) Query: 113 FHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSV 151 +HG +S + EKLL G GS+L+R+S+S PG + L V Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCV 45 >3RO1-A nrPDB Length = 161 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 15/91 (16%) Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKG 483 PD GVPSD L ++ + ++E + VHC GIGRTGT + +++ Sbjct: 68 PDGGVPSD-SQFLTIMKWLLSEKEGNL------VHCVGGIGRTGTILASYLIL------- 113 Query: 484 VDCDIDVPKTIQMVRSQRSGMVQTEAQYRFI 514 ++V I VR R G VQT Q F+ Sbjct: 114 -TEGLEVESAIDEVRLVRPGAVQTYEQEMFL 143 >1RPY-A nrPDB Length = 114 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 14/94 (14%) Query: 112 WFHGHLSGKEAEKLLTEKG--KHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVT- 168 WFHG LS +A +L+ G HG F++R+S++ PG+ VL T + +G++ + + Sbjct: 13 WFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVL---TFNFQGKAKHLRLSLNG 69 Query: 169 HVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPM 202 H Q L F S+ D++ H+ +P+ Sbjct: 70 HGQCHVQHL--------WFQSVFDMLRHFHTHPI 95 Score = 36.2 bits (82), Expect = 0.037, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 2/57 (3%) Query: 6 WFHPNITGVEAENLLLTRG--VDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 WFH ++ V+A L+L G G F+ R S++ PG+ L+ G H+++ G Sbjct: 13 WFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNG 69 >6DR7-A nrPDB Length = 306 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 49/203 (24%), Positives = 82/203 (40%), Gaps = 29/203 (14%) Query: 328 IATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALK-EYGVMRVR 386 IA Q LQ+ + +RM+ + + V+ + E + PD + YG + V Sbjct: 95 IACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRF--GMPDYFRQSGTYGSITVE 152 Query: 387 N--VKESAAHDYTLRE---LKLSKVGQGNTERTVWQYHFRTWPDHGVPSDP-----GGVL 436 + ++ D + + L + + GQ +V H TWPD GVP ++ Sbjct: 153 SKMTQQVGLGDGIMADMYTLTIREAGQKTI--SVPVVHVTTWPDFGVPESEVTKALASLV 210 Query: 437 DFLEEVHHK------QESIMDAGPV--VVHCSAGIGRTGTFIVIDILIDIIREKGVDCDI 488 D E ++ D + V+HC AG+GRT I + D + + Sbjct: 211 DQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMND-----SRNSQL 265 Query: 489 DVPKTIQMVRSQRSG-MVQTEAQ 510 V + +R QR+G MVQ + Q Sbjct: 266 SVEDMVSQMRVQRNGIMVQKDEQ 288 >1G4W-R nrPDB Length = 383 Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust. Identities = 33/145 (22%), Positives = 59/145 (40%), Gaps = 17/145 (11%) Query: 343 RMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELK 402 +M+ ++ +V+ T E + + Y+ Y +G + + K S+A + Sbjct: 202 KMLLEKECSCLVVLTSEDQMQAKQLPPYFRGSYT---FGEVHTNSQKVSSASQGEAIDQY 258 Query: 403 LSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHK-QESIMDAGP------- 454 ++ G T+ H + WPDH P D LE + + + S + P Sbjct: 259 NMQLSCGEKRYTIPVLHVKNWPDH----QPLPSTDQLEYLADRVKNSNQNGAPGRSSSDK 314 Query: 455 --VVVHCSAGIGRTGTFIVIDILID 477 ++HC G+GRTGT +L D Sbjct: 315 HLPMIHCLGGVGRTGTMAAALVLKD 339 >5M6U-B nrPDB Length = 724 Score = 38.5 bits (88), Expect = 0.009, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 12/94 (12%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHP-GDFVLSVRTGDDKGESNDGKSKVTHV 170 W+ G +S +E + L + G+FLVR++ + GD+ L++R G G +K+ + Sbjct: 333 WYWGDISREEVNEKLRDTAD-GTFLVRDASTKMHGDYTLTLRKG--------GNNKLIKI 383 Query: 171 MIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE 204 R + KY F S+ +L+ HY+ + + Sbjct: 384 FHR--DGKYGFSDPLTFSSVVELINHYRNESLAQ 415 Score = 38.5 bits (88), Expect = 0.009, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 5/100 (5%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNP-GDFTLSVRRNGAVTHIKIQNTGDYYD 64 W+ +I+ E N L DG+FL R + + GD+TL++R+ G IKI + Y Sbjct: 333 WYWGDISREEV-NEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYG 391 Query: 65 LYGGEKFATLAELVQYYMEHHGQLKEKNGDV-IELKYPLN 103 F+++ EL+ +Y + L + N + ++L YP++ Sbjct: 392 FSDPLTFSSVVELINHY--RNESLAQYNPKLDVKLLYPVS 429 >3QWY-A nrPDB Length = 308 Score = 38.1 bits (87), Expect = 0.010, Method: Compositional matrix adjust. Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 17/112 (15%) Query: 103 NCADPTSERWFH-GHLSGKEAEKLLTE-KGKHGSFLVRESQSHPGDFVLSVRTGDDKGES 160 N DP R F+ +S +EA KLL E + G+FL+R+S S PG++ L+VR D+ Sbjct: 33 NGFDPFEWRSFYFPGMSREEAHKLLGEPQVSIGTFLMRDS-SRPGEYSLTVREADE---- 87 Query: 161 NDGKSKVTHVMIRCQELKYD--VGGG-----ERFDSLTDLVEHYKKNPMVET 205 + V H +I E K D G + F + L+ H+K + E Sbjct: 88 ---GNAVCHYLIERGEPKEDGTAAAGVKIANQSFPDIPALLNHFKMRVLTEA 136 Score = 30.0 bits (66), Expect = 2.8, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%) Query: 4 RRWFHPNITGVEAENLLLTRGVD-GSFLARPSKSNPGDFTLSVR---RNGAVTHIKIQ 57 R ++ P ++ EA LL V G+FL R S S PG+++L+VR AV H I+ Sbjct: 41 RSFYFPGMSREEAHKLLGEPQVSIGTFLMRDS-SRPGEYSLTVREADEGNAVCHYLIE 97 >4E93-A nrPDB Length = 377 Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust. Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 17/113 (15%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 W+HG + E +LL G FLVRESQ ++VLSV DG + H + Sbjct: 15 WYHGAIPRAEVAELLVHS---GDFLVRESQGK-QEYVLSVLW--------DGLPR--HFI 60 Query: 172 IRCQELKYDVGGGERFDSLTDLVEHY--KKNPMVETLGTVLQLKQPLNTTRIN 222 I+ + Y + GE F S+ L++H + P+ + G VL P + +N Sbjct: 61 IQSLDNLYRL-EGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVPKDKWVLN 112 >4GL9-E nrPDB Length = 143 Score = 37.7 bits (86), Expect = 0.013, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 8/84 (9%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 ++ +TG EA NLLL+ G+FL R S FTLSV+ +++IQ G + L Sbjct: 30 FYWSAVTGGEA-NLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSL 88 Query: 66 YGG-------EKFATLAELVQYYM 82 +F + +LV +YM Sbjct: 89 QSDPRSTQPVPRFDCVLKLVHHYM 112 Score = 32.0 bits (71), Expect = 0.73, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 18/93 (19%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 ++ ++G EA LL+ + G+FL+R+S F LSV+T +S ++ Sbjct: 30 FYWSAVTGGEANLLLSAE-PAGTFLIRDSSDQRHFFTLSVKT----------QSGTKNLR 78 Query: 172 IRCQELKYDVGGG-------ERFDSLTDLVEHY 197 I+C+ + + RFD + LV HY Sbjct: 79 IQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHY 111 >2HMH-A nrPDB Length = 152 Score = 37.7 bits (86), Expect = 0.014, Method: Composition-based stats. Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 8/79 (10%) Query: 11 ITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGG-- 68 +TG EA NLLL+ G+FL R S FTLSV+ +++IQ G + L Sbjct: 41 VTGGEA-NLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPR 99 Query: 69 -----EKFATLAELVQYYM 82 +F + +LV +YM Sbjct: 100 STQPVPRFDCVLKLVHHYM 118 Score = 32.0 bits (71), Expect = 0.76, Method: Composition-based stats. Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 18/88 (20%) Query: 117 LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQ- 175 ++G EA LL+ + G+FL+R+S F LSV+T +S ++ I+C+ Sbjct: 41 VTGGEANLLLSAE-PAGTFLIRDSSDQRHFFTLSVKT----------QSGTKNLRIQCEG 89 Query: 176 ---ELKYDVGGGE---RFDSLTDLVEHY 197 L+ D + RFD + LV HY Sbjct: 90 GSFSLQSDPRSTQPVPRFDCVLKLVHHY 117 >2BBU-A nrPDB Length = 164 Score = 37.4 bits (85), Expect = 0.018, Method: Composition-based stats. Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 8/83 (9%) Query: 11 ITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGG-- 68 +TG EA NLLL+ G+FL R S FTLSV+ +++IQ G + L Sbjct: 30 VTGGEA-NLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPR 88 Query: 69 -----EKFATLAELVQYYMEHHG 86 +F + +LV +YM G Sbjct: 89 STQPVPRFDCVLKLVHHYMPPPG 111 Score = 32.7 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 18/92 (19%) Query: 117 LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQ- 175 ++G EA LL+ + G+FL+R+S F LSV+T +S ++ I+C+ Sbjct: 30 VTGGEANLLLSAE-PAGTFLIRDSSDQRHFFTLSVKT----------QSGTKNLRIQCEG 78 Query: 176 ---ELKYDVGGGE---RFDSLTDLVEHYKKNP 201 L+ D + RFD + LV HY P Sbjct: 79 GSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPP 110 >5Z59-A nrPDB Length = 147 Score = 36.6 bits (83), Expect = 0.035, Method: Composition-based stats. Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 16/101 (15%) Query: 418 YHFRTWPDHGVPSDPGGVLDF--------LEEVHHKQESIMDAGPVVVHCSAGIGRTGTF 469 Y W GV G + DF LE + +E + + V++HC G+GR+GT Sbjct: 44 YSLDEWEKRGVEVLHGPIPDFTAPSVEQLLEILRWIEERVREGKKVLIHCMGGLGRSGTV 103 Query: 470 IVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ 510 V ++ +G + + + + VR +R G V+T+ Q Sbjct: 104 GVAWLMY----SRG----LSLREALMEVRRKRPGAVETQEQ 136 >1OHC-A nrPDB Length = 348 Score = 36.2 bits (82), Expect = 0.044, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 15/90 (16%) Query: 416 WQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDIL 475 + +H + D P+D V +FL+ + + G + VHC AG+GRTGT I I+ Sbjct: 240 FDHHDLFFADGSTPTD-AIVKEFLDICENAE------GAIAVHCKAGLGRTGTLIACYIM 292 Query: 476 IDIIREKGVDCDIDVPKTIQMVRSQRSGMV 505 + +TI VR R G V Sbjct: 293 KHY--------RMTAAETIAWVRICRPGSV 314 >5LXQ-B nrPDB Length = 196 Score = 36.2 bits (82), Expect = 0.044, Method: Compositional matrix adjust. Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 26/133 (19%) Query: 377 LKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP-DHGVPSDPGGV 435 LK+YGV + V E A +D TL E K G H WP D G P V Sbjct: 60 LKKYGVTTIVRVCE-ATYDTTLVE----KEG----------IHVLDWPFDDGAPPSNQIV 104 Query: 436 LDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQ 495 D+L V K + VHC AG+GR + + ++ E G+ + +Q Sbjct: 105 DDWLSLVKIKFRE-EPGCCIAVHCVAGLGRAPVLVALALI-----EGGMKYE----DAVQ 154 Query: 496 MVRSQRSGMVQTE 508 +R +R G ++ Sbjct: 155 FIRQKRRGAFNSK 167 >6C7Y-B nrPDB Length = 117 Score = 35.8 bits (81), Expect = 0.058, Method: Composition-based stats. Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 13/80 (16%) Query: 123 EKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVG 182 EKL +E G+FL+R+S F +SV+T + T + I Q ++ + Sbjct: 40 EKLKSEP--EGTFLIRDSTQKNCFFAISVKTA----------TGPTSIRINFQTGRFSLD 87 Query: 183 GG-ERFDSLTDLVEHYKKNP 201 G E FD L L+EHY +P Sbjct: 88 GSKETFDCLFKLLEHYLSSP 107 >5K23-A nrPDB Length = 189 Score = 35.8 bits (81), Expect = 0.060, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 11/91 (12%) Query: 419 HFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 477 H WP D G P V D+L + K V VHC AG+GR + + + Sbjct: 83 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFRE-EPGCCVAVHCVAGLGRAPVLVALAL--- 138 Query: 478 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTE 508 ++C + +Q +R +R G ++ Sbjct: 139 ------IECGMKYEDAVQFIRQKRRGAFNSK 163 >1ZCK-A nrPDB Length = 154 Score = 35.4 bits (80), Expect = 0.065, Method: Compositional matrix adjust. Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 26/133 (19%) Query: 377 LKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP-DHGVPSDPGGV 435 LK+YGV + V E A +D TL E K G H WP D G P V Sbjct: 31 LKKYGVTTIVRVCE-ATYDTTLVE----KEG----------IHVLDWPFDDGAPPSNQIV 75 Query: 436 LDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQ 495 D+L V K + VHC AG+GR + + ++ E G+ + +Q Sbjct: 76 DDWLSLVKIKFRE-EPGCCIAVHCVAGLGRAPVLVALALI-----EGGMKYE----DAVQ 125 Query: 496 MVRSQRSGMVQTE 508 +R +R G ++ Sbjct: 126 FIRQKRRGAFNSK 138 >3RZ2-A nrPDB Length = 189 Score = 35.0 bits (79), Expect = 0.086, Method: Compositional matrix adjust. Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 26/133 (19%) Query: 377 LKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP-DHGVPSDPGGV 435 LK+YGV + V E A +D TL E K G H WP D G P V Sbjct: 57 LKKYGVTTIVRVCE-ATYDTTLVE----KEG----------IHVLDWPFDDGAPPSNQIV 101 Query: 436 LDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQ 495 D+L V K + VHC AG+GR + + ++ E G+ + +Q Sbjct: 102 DDWLSLVKIKFRE-EPGCCIAVHCVAGLGRAPVLVALALI-----EGGMKYE----DAVQ 151 Query: 496 MVRSQRSGMVQTE 508 +R +R G ++ Sbjct: 152 FIRQKRRGAFNSK 164 >1V3A-A nrPDB Length = 173 Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 13/88 (14%) Query: 423 WP-DHGVPSDPGGVL-DFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 480 WP D G P PG V+ D+L V K V VHC AG+GR + + ++ Sbjct: 68 WPFDDGAPP-PGKVVEDWLSLVKAKFCE-APGSCVAVHCVAGLGRAPVLVALALI----- 120 Query: 481 EKGVDCDIDVPKTIQMVRSQRSGMVQTE 508 E G+ + IQ +R +R G + ++ Sbjct: 121 ESGMKYE----DAIQFIRQKRRGAINSK 144 >5K22-A nrPDB Length = 183 Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust. Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 11/91 (12%) Query: 419 HFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 477 H WP D G P V D+L + K A V VHC AG+GR + + ++ Sbjct: 81 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGAA-VAVHCVAGLGRAPVLVALALI-- 137 Query: 478 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTE 508 E G+ + +Q +R +R G ++ Sbjct: 138 ---EAGMKYE----DAVQFIRQKRRGAFNSK 161 >5IXI-A nrPDB Length = 544 Score = 33.5 bits (75), Expect = 0.27, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Query: 114 HGHLSGKEA-EKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI 172 HG + + A KL E + G +++R S + + +++V + + + + + I Sbjct: 423 HGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEQVQGAQKQFKNFQI 482 Query: 173 RCQELKYDVGGGER-FDSLTDLVEHYKK 199 Q+ +Y + G +R F SL DL+ H KK Sbjct: 483 EVQKGRYSLHGSDRSFPSLGDLMSHLKK 510 >3F41-A nrPDB Length = 629 Score = 33.1 bits (74), Expect = 0.34, Method: Compositional matrix adjust. Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 6/80 (7%) Query: 419 HFR-TWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 477 +FR T DH P DP V FLE +S+ + HC AG+GRT F+V+ ++ Sbjct: 203 YFRLTLQDHFRPDDPD-VDKFLEFY----KSLPKDAWLHYHCYAGMGRTTIFMVMHDILK 257 Query: 478 IIREKGVDCDIDVPKTIQMV 497 ++ D I K I +V Sbjct: 258 NAKDVSFDDIIQRQKLIGIV 277 >6C5X-D nrPDB Length = 164 Score = 32.7 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 11/70 (15%) Query: 133 GSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGG-ERFDSLT 191 G+FL+R+S+ F +SV+T + + I+ K+ + G E F L Sbjct: 52 GTFLIRDSKQKNCFFAISVKTA----------RETVSIRIKFHAGKFSLDGSKELFSCLF 101 Query: 192 DLVEHYKKNP 201 LVEHY +P Sbjct: 102 QLVEHYMTSP 111 >4ERC-A nrPDB Length = 150 Score = 32.7 bits (73), Expect = 0.42, Method: Composition-based stats. Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 12/96 (12%) Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKG 483 PD P P + F++ V E+ V VHC+ G GRTGT + +++E+G Sbjct: 64 PDF-CPPAPDQIDRFVQIV---DEANARGEAVGVHCALGFGRTGTMLA----CYLVKERG 115 Query: 484 VDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQ 519 + I +R R G ++T Q + ++ Q Sbjct: 116 ----LAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQ 147 >2OZ5-A nrPDB Length = 296 Score = 32.0 bits (71), Expect = 0.74, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 12/70 (17%) Query: 444 HKQESIMDAG-PVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVP------KTIQM 496 H+ +++ AG PV+ HC AG RTG + + ++ G+D D+ V ++ Sbjct: 164 HRVVTLLAAGRPVLTHCFAGKDRTGFVVAL-----VLEAVGLDRDVIVADYLRSNDSVPQ 218 Query: 497 VRSQRSGMVQ 506 +R++ S M+Q Sbjct: 219 LRARISEMIQ 228 >5XW4-A nrPDB Length = 415 Score = 32.0 bits (71), Expect = 0.80, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 8/63 (12%) Query: 449 IMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTE 508 I G + VHC AG+GRTG I +I G + + I +R R GMV Sbjct: 314 IKRGGKIAVHCKAGLGRTGCLIG----AHLIYTYGFTAN----ECIGFLRFIRPGMVVGP 365 Query: 509 AQY 511 Q+ Sbjct: 366 QQH 368 >4NX8-A nrPDB Length = 293 Score = 31.6 bits (70), Expect = 0.97, Method: Compositional matrix adjust. Identities = 26/70 (37%), Positives = 32/70 (45%), Gaps = 8/70 (11%) Query: 417 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 QY T DH P D V F+E V E+ V HC AG GRT TF+V L Sbjct: 169 QYVRLTVTDHVRPVD-SEVDRFIESVRALPENAW----VHFHCRAGKGRTTTFMV---LY 220 Query: 477 DIIREKGVDC 486 D+++ D Sbjct: 221 DMLKNAKTDS 230 >1G85-A nrPDB Length = 159 Score = 31.2 bits (69), Expect = 1.4, Method: Compositional matrix adjust. Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 13/112 (11%) Query: 40 DFTLSVRRNGAVTHIKI----QNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDV 95 DF SV+R+G ++ + Q+ G Y Y G+ + L + ++ H +K+G Sbjct: 53 DFYFSVKRDGKWKNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVAHNINVDKHGQT 112 Query: 96 IELK---YPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHP 144 EL LN D E+++ K E +K +FL E+ HP Sbjct: 113 TELTGLFVKLNVEDEDLEKFW------KLTEDKGIDKKNVVNFLENENHPHP 158 >5BO8-A nrPDB Length = 343 Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 6/44 (13%) Query: 77 LVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 120 LV +++EH GQLK ++L +P N + W + HLS K Sbjct: 223 LVDFFVEHRGQLK------VQLAWPGNIMQHVNRYWKNKHLSPK 260 >2M3V-A nrPDB Length = 193 Score = 30.8 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 4/46 (8%) Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTF 469 P H D VL L ++ + GPV++HC G RTG F Sbjct: 76 PTHADRVDDAEVLSVLRQLQAAERE----GPVLMHCKHGNNRTGLF 117 >5BO9-A nrPDB Length = 323 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 6/44 (13%) Query: 77 LVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 120 LV +++EH GQLK ++L +P N + W + HLS K Sbjct: 203 LVDFFVEHRGQLK------VQLAWPGNIMQHVNRYWKNKHLSPK 240 >4R0S-A nrPDB Length = 218 Score = 30.0 bits (66), Expect = 2.8, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 4/49 (8%) Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVI 472 P H D VL L ++ + GPV++HC G RTG F + Sbjct: 101 PTHADRVDDAEVLSVLRQLQAAERE----GPVLMHCKHGNNRTGLFAAM 145 >5UJY-A nrPDB Length = 706 Score = 29.6 bits (65), Expect = 3.8, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 394 HDYTLR-ELKLSKVGQGNTERTVWQYHFRTWPDHGVP 429 +D+T E +L ++ GN RT W +F DHGVP Sbjct: 582 YDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVP 618 >4JGH-A nrPDB Length = 173 Score = 29.3 bits (64), Expect = 5.0, Method: Compositional matrix adjust. Identities = 28/116 (24%), Positives = 54/116 (46%), Gaps = 14/116 (12%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 W+ ++T EA+ L +G+FL R S + T+SV+ + T+++I+ + L Sbjct: 23 WYWGSMTVNEAKEKL-KEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRL 81 Query: 66 -------YGGEKFATLAELVQYYME-----HHGQLKEKNGDV-IELKYPLNCADPT 108 ++F ++ L+ YY++ G +NG V + L PL + P+ Sbjct: 82 DSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPS 137 >4MIF-A nrPDB Length = 620 Score = 28.9 bits (63), Expect = 6.4, Method: Compositional matrix adjust. Identities = 34/139 (24%), Positives = 54/139 (38%), Gaps = 19/139 (13%) Query: 13 GVEAENLLLTRGVDGS----FLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGG 68 G EA +TRGV G A P P DF R ++ ++ + DLY Sbjct: 144 GAEA----VTRGVGGMSTHWTCATPEFFAPADFNAPHRERPKLSTDAAEDARIWKDLYAQ 199 Query: 69 EK--FATLAELVQYYMEHHGQLKEKNGDVIELK--------YPLNCADPTSERWFHGHLS 118 K T + + H+ L++ N D+ + + PL C T + H + Sbjct: 200 AKEIIGTSTTEFDHSIRHNLVLRKYN-DIFQKENVIREFSPLPLACHRLTDPDYVEWHAT 258 Query: 119 GKEAEKLLTEKGKHGSFLV 137 + E+L T+ K G F + Sbjct: 259 DRILEELFTDPVKRGRFTL 277 >4PKA-X nrPDB Length = 373 Score = 28.9 bits (63), Expect = 6.9, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 24/59 (40%), Gaps = 18/59 (30%) Query: 60 GDYYDLYGGEK------------------FATLAELVQYYMEHHGQLKEKNGDVIELKY 100 DY+D+ GG FA E+V +Y EH Q+ +G ++ KY Sbjct: 54 ADYFDVIGGTSTGGLLTAMISTPNENNRPFAAAKEIVPFYFEHGPQIFNPSGQILGPKY 112 >5BPD-A nrPDB Length = 264 Score = 28.5 bits (62), Expect = 8.9, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 37/63 (58%), Gaps = 7/63 (11%) Query: 486 CDIDVPKTIQMVRS-QRSGMVQTEA----QYRFIYMA--VQHYIETLQRRIEEEQKSKRK 538 ++ P+T ++RS ++ G T+ +YR ++ A ++ +I+ Q R++EE ++K+K Sbjct: 42 SEVPAPRTYDVLRSLEKKGFAMTQPGKTNKYRPVHPANVLEKFIQDWQERVKEELEAKKK 101 Query: 539 GHE 541 E Sbjct: 102 AKE 104 >4IFQ-A nrPDB Length = 970 Score = 28.5 bits (62), Expect = 9.0, Method: Compositional matrix adjust. Identities = 17/83 (20%), Positives = 36/83 (43%), Gaps = 3/83 (3%) Query: 219 TRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNR 278 T+IN + + + +S L + + FW ++L ++ L YS + + + Sbjct: 645 TKINTPLVGAAFKVISNLVPKLESSRTKFWSFLDSLIFKDSSLNYSSESYRNAFTNVLTK 704 Query: 279 YKNILPF---DHTRVVLHDGDPN 298 Y ++L F H + +H + N Sbjct: 705 YSDVLGFLQLFHNLISIHSRENN 727 >4ZO7-A nrPDB Length = 731 Score = 28.5 bits (62), Expect = 9.1, Method: Compositional matrix adjust. Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 3/99 (3%) Query: 92 NGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVL-- 149 NG +E+K +D E WF G +G+ LL+ L G + Sbjct: 506 NGRPLEVKELAESSDALLELWFPGTEAGRVTADLLSGASNPSGKLSMSFPQTTGQIPVYY 565 Query: 150 -SVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERF 187 +RTG + N G+ V+H + E Y G G+ + Sbjct: 566 NHLRTGRPQTPENKGERYVSHYLDIPNEPFYPFGYGKSY 604 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4H1O-A nrPDB 814 0.0 3PS5-A nrPDB 732 0.0 2B3O-A nrPDB 721 0.0 6CMQ-A nrPDB 636 0.0 4PVG-A nrPDB 468 e-132 4HJQ-A nrPDB 431 e-121 1YGU-A nrPDB 415 e-116 2NLK-A nrPDB 407 e-114 2C7S-A nrPDB 394 e-110 2OOQ-A nrPDB 393 e-109 2PBN-A nrPDB 388 e-108 6D4D-A nrPDB 387 e-108 2JJD-A nrPDB 385 e-107 4BPC-A nrPDB 384 e-107 2NV5-A nrPDB 383 e-106 1LAR-A nrPDB 382 e-106 3I36-A nrPDB 379 e-105 1RPM-A nrPDB 377 e-105 2H03-A nrPDB 377 e-104 1YFO-A nrPDB 376 e-104 5AWX-A nrPDB 374 e-104 2CFV-A nrPDB 372 e-103 3S3F-A nrPDB 364 e-101 2PI7-A nrPDB 362 e-100 2GJT-A nrPDB 359 2e-99 2I75-A nrPDB 358 3e-99 2I1Y-A nrPDB 357 1e-98 3OLR-A nrPDB 355 3e-98 1WCH-A nrPDB 353 8e-98 2QEP-A nrPDB 353 1e-97 4IKC-A nrPDB 352 3e-97 5HDE-A nrPDB 348 3e-96 1P15-A nrPDB 347 1e-95 4RHG-A nrPDB 345 3e-95 4BJO-A nrPDB 341 4e-94 6D3F-A nrPDB 338 3e-93 4GE6-A nrPDB 338 5e-93 4GFV-A nrPDB 337 1e-92 2A8B-A nrPDB 334 7e-92 1ZC0-A nrPDB 330 2e-90 1L8K-A nrPDB 325 4e-89 2BZL-A nrPDB 323 1e-88 6H8S-A nrPDB 313 2e-85 5OVR-A nrPDB 312 3e-85 4AZ1-A nrPDB 272 4e-73 3M4U-A nrPDB 272 4e-73 4FL3-A nrPDB 170 1e-42 1A81-A nrPDB 170 2e-42 2OZO-A nrPDB 147 1e-35 4XZ1-A nrPDB 145 6e-35 1AD5-A nrPDB 124 1e-28 2H8H-A nrPDB 118 6e-27 6F3F-A nrPDB 118 8e-27 1K9A-A nrPDB 117 1e-26 2FO0-A nrPDB 117 1e-26 4XEY-B nrPDB 117 2e-26 2ABL-A nrPDB 117 2e-26 6AMW-A nrPDB 116 2e-26 2KK6-A nrPDB 115 7e-26 2AUG-A nrPDB 114 9e-26 3T04-A nrPDB 114 1e-25 1GRI-A nrPDB 113 2e-25 5U06-A nrPDB 110 2e-24 1NRV-A nrPDB 110 2e-24 2EOB-A nrPDB 107 2e-23 2PLE-A nrPDB 107 2e-23 2EKX-A nrPDB 103 2e-22 2CRH-A nrPDB 99 6e-21 2LCT-A nrPDB 98 8e-21 4XI2-A nrPDB 98 1e-20 2LQW-A nrPDB 98 1e-20 4M4Z-A nrPDB 97 2e-20 1MIL-A nrPDB 94 2e-19 2CS0-A nrPDB 92 6e-19 1KA6-A nrPDB 91 1e-18 1M27-A nrPDB 90 2e-18 3RO1-A nrPDB 87 3e-17 2HDV-A nrPDB 83 4e-16 2EYZ-A nrPDB 82 9e-16 1RPY-A nrPDB 81 2e-15 1XA6-A nrPDB 74 2e-13 3CXL-A nrPDB 73 3e-13 Sequences not found previously or not previously below threshold: 6DR7-A nrPDB 97 2e-20 4E93-A nrPDB 87 3e-17 5M6U-B nrPDB 74 1e-13 2VIF-A nrPDB 69 7e-12 3QWY-A nrPDB 63 3e-10 4JGH-A nrPDB 60 3e-09 4ERC-A nrPDB 59 7e-09 6C5X-D nrPDB 57 2e-08 2HMH-A nrPDB 56 4e-08 4GL9-E nrPDB 56 5e-08 2BBU-A nrPDB 56 5e-08 6C7Y-B nrPDB 55 1e-07 5Z59-A nrPDB 55 1e-07 1G4W-R nrPDB 54 3e-07 5LXQ-B nrPDB 51 2e-06 3RZ2-A nrPDB 51 2e-06 1ZCK-A nrPDB 51 2e-06 5K23-A nrPDB 49 7e-06 5XW4-A nrPDB 49 9e-06 1V3A-A nrPDB 48 1e-05 1OHC-A nrPDB 48 1e-05 2EL8-A nrPDB 47 2e-05 1XM2-A nrPDB 47 2e-05 5K22-A nrPDB 47 2e-05 3S4O-A nrPDB 45 8e-05 1FPZ-A nrPDB 44 2e-04 2CR4-A nrPDB 44 3e-04 5BZX-A nrPDB 43 3e-04 3V0J-A nrPDB 43 4e-04 1UUS-A nrPDB 42 7e-04 2WGP-A nrPDB 42 9e-04 5T2H-A nrPDB 42 0.001 2IZV-A nrPDB 40 0.002 3MAZ-A nrPDB 40 0.002 4Z32-A nrPDB 40 0.004 2G6Z-A nrPDB 39 0.004 2RF6-A nrPDB 39 0.006 4NX8-A nrPDB 38 0.010 5THG-A nrPDB 38 0.012 4R0S-A nrPDB 37 0.033 3D1Q-A nrPDB 37 0.034 2M3V-A nrPDB 36 0.042 4YR8-G nrPDB 35 0.075 2OZ5-A nrPDB 35 0.087 5T2O-A nrPDB 35 0.093 6N8N-Y nrPDB 35 0.11 6BDA-A nrPDB 35 0.12 1Y1U-A nrPDB 35 0.13 1M3G-A nrPDB 34 0.15 6D67-A nrPDB 34 0.15 3EZZ-A nrPDB 34 0.16 1WRM-A nrPDB 34 0.18 3F41-A nrPDB 34 0.23 1YN9-A nrPDB 34 0.24 5GQY-A nrPDB 33 0.35 4B04-A nrPDB 33 0.39 5GTJ-A nrPDB 33 0.40 1ZZW-A nrPDB 32 0.66 2OUD-A nrPDB 32 0.67 3ZID-A nrPDB 32 0.69 4JMK-A nrPDB 32 0.74 5T2N-A nrPDB 32 0.78 2R0B-A nrPDB 32 0.89 2Q47-A nrPDB 32 1.0 3LJ8-A nrPDB 32 1.1 4Y5W-A nrPDB 32 1.1 5NCR-A nrPDB 32 1.1 3E6P-L nrPDB 31 1.3 4MBB-A nrPDB 31 1.4 5WB5-A nrPDB 31 1.4 4NZQ-A nrPDB 31 1.4 2ESB-A nrPDB 31 1.6 3NXP-A nrPDB 31 1.7 4KYQ-A nrPDB 31 1.8 2R51-A nrPDB 31 1.8 3G5W-A nrPDB 30 2.0 2G2B-A nrPDB 30 2.0 2J16-A nrPDB 30 2.2 5T8D-A nrPDB 30 2.9 4Y2E-A nrPDB 30 4.1 4PO6-A nrPDB 29 4.9 4A5P-A nrPDB 29 5.2 2BN8-A nrPDB 29 6.7 >4H1O-A nrPDB Length = 560 Score = 814 bits (2102), Expect = 0.0, Method: Composition-based stats. Identities = 538/539 (99%), Positives = 538/539 (99%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG Sbjct: 22 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 81 Query: 61 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 120 YYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK Sbjct: 82 GYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 141 Query: 121 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 180 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD Sbjct: 142 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 201 Query: 181 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 240 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT Sbjct: 202 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 261 Query: 241 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 300 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP Sbjct: 262 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 321 Query: 301 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 360 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV Sbjct: 322 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 381 Query: 361 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF 420 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF Sbjct: 382 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF 441 Query: 421 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 480 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR Sbjct: 442 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 501 Query: 481 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG 539 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG Sbjct: 502 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG 560 >3PS5-A nrPDB Length = 595 Score = 732 bits (1889), Expect = 0.0, Method: Composition-based stats. Identities = 318/546 (58%), Positives = 406/546 (74%), Gaps = 4/546 (0%) Query: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64 RWFH +++G++AE LL RGV GSFLARPS+ N GDF+LSVR VTHI+IQN+GD+YD Sbjct: 3 RWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62 Query: 65 LYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEK 124 LYGGEKFATL ELV+YY + G L++++G +I LKYPLNC+DPTSERW+HGH+SG +AE Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAET 122 Query: 125 LLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGG 184 LL KG+ +FLVRES S PGDFVLSV + K +VTH+ + C+ +Y VGG Sbjct: 123 LLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSP-LRVTHIKVMCEGGRYTVGGL 181 Query: 185 ERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVK 244 E FDSLTDLVEH+KK + E G + L+QP TR+NAA+IE+RV EL+K E+ D K Sbjct: 182 ETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAK 241 Query: 245 QGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDY 304 GFWEEFE+LQ+QE K L+ R EGQR ENK KNRYKNILPFDH+RV+L D N P SDY Sbjct: 242 AGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDY 301 Query: 305 INANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGK 364 INAN I + N+ K+YIA+QGCL+ TVNDFW+M +QENSRVIVMTT+EVE+G+ Sbjct: 302 INANYIKNQLLGPDENA---KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGR 358 Query: 365 SKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP 424 +KCV YWP+ + YG V N E +Y LR L++S + G+ R +W Y + +WP Sbjct: 359 NKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWP 418 Query: 425 DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGV 484 DHGVPS+PGGVL FL++++ +QES+ AGP++VH SAGIGRTGT IVID+L++ I KG+ Sbjct: 419 DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMENISTKGL 478 Query: 485 DCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTN 544 DCDID+ KTIQMVR+QRSGMVQTEAQY+FIY+A+ +IET ++++E Q K + EY N Sbjct: 479 DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGN 538 Query: 545 IKYSLA 550 I Y A Sbjct: 539 ITYPPA 544 Score = 99.0 bits (245), Expect = 6e-21, Method: Composition-based stats. Identities = 40/109 (36%), Positives = 61/109 (55%), Gaps = 11/109 (10%) Query: 2 TSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNG---------AVT 52 TS RW+H +++G +AE LL +G +FL R S S PGDF LSV + VT Sbjct: 106 TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVT 165 Query: 53 HIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 HIK+ G Y + G E F +L +LV+++ + ++E +G + L+ P Sbjct: 166 HIKVMCEGGRYTVGGLETFDSLTDLVEHFKKT--GIEEASGAFVYLRQP 212 >2B3O-A nrPDB Length = 532 Score = 721 bits (1862), Expect = 0.0, Method: Composition-based stats. Identities = 313/534 (58%), Positives = 401/534 (75%), Gaps = 4/534 (0%) Query: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64 RWFH +++G++AE LL RGV GSFLARPS+ N GDF+LSVR VTHI+IQN+GD+YD Sbjct: 3 RWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62 Query: 65 LYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEK 124 LYGGEKFATL ELV+YY + G L++++G +I LKYPLNC+DPTSERW+HGH+SG +AE Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAET 122 Query: 125 LLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGG 184 LL KG+ +FLVRES S PGDFVLSV + K +VTH+ + C+ +Y VGG Sbjct: 123 LLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSP-LRVTHIKVMCEGGRYTVGGL 181 Query: 185 ERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVK 244 E FDSLTDLVEH+KK + E G + L+QP TR+NAA+IE+RV EL+K E+ D K Sbjct: 182 ETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAK 241 Query: 245 QGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDY 304 GFWEEFE+LQ+QE K L+ R EGQR ENK KNRYKNILPFDH+RV+L D N P SDY Sbjct: 242 AGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDY 301 Query: 305 INANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGK 364 INAN I + N+ K+YIA+QGCL+ TVNDFW+M +QENSRVIVMTT+EVE+G+ Sbjct: 302 INANYIKNQLLGPDENA---KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGR 358 Query: 365 SKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP 424 +KCV YWP+ + YG V N E +Y LR L++S + G+ R +W Y + +WP Sbjct: 359 NKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWP 418 Query: 425 DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGV 484 DHGVPS+PGGVL FL++++ +QES+ AGP++VHCSAGIGRTGT IVID+L++ I KG+ Sbjct: 419 DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGL 478 Query: 485 DCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRK 538 DCDID+ KTIQMVR+QRSGMVQTEAQY+FIY+A+ +IET ++++E Q K + Sbjct: 479 DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ 532 Score = 99.4 bits (246), Expect = 4e-21, Method: Composition-based stats. Identities = 40/109 (36%), Positives = 61/109 (55%), Gaps = 11/109 (10%) Query: 2 TSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNG---------AVT 52 TS RW+H +++G +AE LL +G +FL R S S PGDF LSV + VT Sbjct: 106 TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVT 165 Query: 53 HIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 HIK+ G Y + G E F +L +LV+++ + ++E +G + L+ P Sbjct: 166 HIKVMCEGGRYTVGGLETFDSLTDLVEHFKKT--GIEEASGAFVYLRQP 212 >6CMQ-A nrPDB Length = 427 Score = 636 bits (1640), Expect = 0.0, Method: Composition-based stats. Identities = 424/426 (99%), Positives = 424/426 (99%) Query: 104 CADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDG 163 DPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDG Sbjct: 2 SGDPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDG 61 Query: 164 KSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINA 223 KSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINA Sbjct: 62 KSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINA 121 Query: 224 AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNIL 283 AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNIL Sbjct: 122 AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNIL 181 Query: 284 PFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWR 343 PFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWR Sbjct: 182 PFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWR 241 Query: 344 MVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKL 403 MVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKL Sbjct: 242 MVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKL 301 Query: 404 SKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGI 463 SKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGI Sbjct: 302 SKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGI 361 Query: 464 GRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE 523 GRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE Sbjct: 362 GRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE 421 Query: 524 TLQRRI 529 TLQRRI Sbjct: 422 TLQRRI 427 Score = 123 bits (309), Expect = 2e-28, Method: Composition-based stats. Identities = 50/112 (44%), Positives = 69/112 (61%), Gaps = 12/112 (10%) Query: 2 TSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRN----------GAV 51 TS RWFH +++G EAE LL +G GSFL R S+S+PGDF LSVR V Sbjct: 6 TSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKV 65 Query: 52 THIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 TH+ I+ YD+ GGE+F +L +LV++Y ++ + E G V++LK PLN Sbjct: 66 THVMIRCQELKYDVGGGERFDSLTDLVEHYKKN--PMVETLGTVLQLKQPLN 115 >4PVG-A nrPDB Length = 298 Score = 468 bits (1204), Expect = e-132, Method: Composition-based stats. Identities = 290/291 (99%), Positives = 291/291 (100%) Query: 240 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE 299 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE Sbjct: 2 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE 61 Query: 300 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE 359 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE Sbjct: 62 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE 121 Query: 360 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH 419 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH Sbjct: 122 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH 181 Query: 420 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII 479 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII Sbjct: 182 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII 241 Query: 480 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIE 530 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRR+E Sbjct: 242 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRLE 292 >4HJQ-A nrPDB Length = 308 Score = 431 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 171/289 (59%), Positives = 220/289 (76%), Gaps = 3/289 (1%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYI 305 GFWEEFE+LQ+QE K L+ R EGQR ENK KNRYKNILPFDH+RV+L D N P SDYI Sbjct: 23 GFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYI 82 Query: 306 NANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKS 365 NAN I + N+ K+YIA+QGCL+ TVNDFW+M +QENSRVIVMTT+EVE+G++ Sbjct: 83 NANYIKNQLLGPDENA---KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRN 139 Query: 366 KCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPD 425 KCV YWP+ + YG V N E +Y LR L++S + G+ R +W Y + +WPD Sbjct: 140 KCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPD 199 Query: 426 HGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVD 485 HGVPS+PGGVL FL++++ +QES+ AGP++VH SAGIGRTGT IVID+L++ I KG+D Sbjct: 200 HGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMENISTKGLD 259 Query: 486 CDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQK 534 CDID+ KTIQMVR+QRSGMVQTEAQY+FIY+A+ +IET ++++E Q Sbjct: 260 CDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQS 308 >1YGU-A nrPDB Length = 610 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 119/349 (34%), Positives = 186/349 (53%), Gaps = 35/349 (10%) Query: 247 FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYIN 306 F EF+++ + K + KE ++ N+NKNRY +ILP+D+ RV L + + + S+YIN Sbjct: 30 FLAEFQSIPRVFSK--FPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAG-SNYIN 86 Query: 307 ANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSK 366 A+ I + K + YIA QG TV+DFWRM++++ + VIVM T+ E ++K Sbjct: 87 ASYI--------DGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNK 138 Query: 367 CVKYWPD-EYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPD 425 C +YWP E + +G + V+ + DY +++L + + T R V F +WPD Sbjct: 139 CAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPD 198 Query: 426 HGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVD 485 HGVP DP +L V+ S +GP+VVH SAG+GRTGT+I ID +++ + + Sbjct: 199 HGVPEDPHLLLKLRRRVN--AFSNFFSGPIVVHSSAGVGRTGTYIGIDAMLEGLEAEN-- 254 Query: 486 CDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNI 545 +DV + +R QR MVQ EAQY I+ A+ Y + E + + + H Y Sbjct: 255 -KVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY-----NQFGETEVNLSELHPY--- 305 Query: 546 KYSLADQTSGDQSPLPPCTPTPPCAEM-REDSARVY--ENVGLMQQQKS 591 L + D PP P+P AE R S R + +++G ++ KS Sbjct: 306 ---LHNMKKRD----PPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKS 347 Score = 233 bits (595), Expect = 1e-61, Method: Composition-based stats. Identities = 86/327 (26%), Positives = 153/327 (46%), Gaps = 44/327 (13%) Query: 219 TRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNR 278 T +N +E+ + + K ++ EF+ L ++ G ++ENK+KNR Sbjct: 295 TEVNLSELHPYLHNMKKRDPPSEPSP--LEAEFQRLPSYRS--WRTQHIGNQEENKSKNR 350 Query: 279 YKNILPFDHTRVVLH------------------DGDPNEPVSDYINANIIMPEFETKCNN 320 N++P+D+ RV L D +E S YINA+ IM Sbjct: 351 NSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMS-------- 402 Query: 321 SKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEY 380 + IA QG L+ T+ DFW+M+FQ +VIVM T+ + C +YW + + Y Sbjct: 403 YWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGE--GKQTY 460 Query: 381 GVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLE 440 G + V + YTLR +L + + RTV+QY + W +P++P ++ ++ Sbjct: 461 GDIEVDLKDTDKSSTYTLRVFEL-RHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQ 519 Query: 441 EVHHK--QESIMD------AGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPK 492 V K Q++ + + P+++HC G +TG F + ++++ + +D+ + Sbjct: 520 VVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCAL---LNLLESAETEEVVDIFQ 576 Query: 493 TIQMVRSQRSGMVQTEAQYRFIYMAVQ 519 ++ +R R GMV T QY+F+Y + Sbjct: 577 VVKALRKARLGMVSTFEQYQFLYDVIA 603 >2NLK-A nrPDB Length = 627 Score = 407 bits (1045), Expect = e-114, Method: Composition-based stats. Identities = 122/320 (38%), Positives = 178/320 (55%), Gaps = 30/320 (9%) Query: 236 LAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHD- 294 + E + GF E+FE +Q+ + + + ENK+KNRY NIL +DH+RV L Sbjct: 12 IGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPL 71 Query: 295 GDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIV 354 + SDYINAN + + K+YIATQG L++T DFWRM++++N+ +IV Sbjct: 72 PGKDSKHSDYINANYV--------DGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIV 123 Query: 355 MTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLREL-----KLSKVGQG 409 M T VE+G+ KC +YWP E + +EYG + V YT+R K+ K +G Sbjct: 124 MITNLVEKGRRKCDQYWPTENS-EEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKG 182 Query: 410 N-----TERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIG 464 N ER V QYH+ WPD GVP VL F+ + + GPV+VHCSAG+G Sbjct: 183 NPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVR--RSSAARMPETGPVLVHCSAGVG 240 Query: 465 RTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIET 524 RTGT+IVID ++ I++K ++V ++ +R+QR+ +VQTE QY FI+ A+ I Sbjct: 241 RTGTYIVIDSMLQQIKDKST---VNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILG 297 Query: 525 LQRRIEEEQKSKRKGHEYTN 544 +E + S + H Y N Sbjct: 298 -----KETEVSSNQLHSYVN 312 Score = 180 bits (456), Expect = 2e-45, Method: Composition-based stats. Identities = 69/303 (22%), Positives = 116/303 (38%), Gaps = 32/303 (10%) Query: 244 KQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSD 303 K ++F+ + Q K + Q++ NK KNR +++P + RV L P +D Sbjct: 322 KTRLEKQFKLVTQCNAKYV-ECFSAQKECNKEKNRNSSVVPSERARVGLAPL-PGMKGTD 379 Query: 304 YINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMT---TKEV 360 YINA+ IM +I TQ L +T DFWRM++ N+++IVM Sbjct: 380 YINASYIM--------GYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLA 431 Query: 361 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAA-----HDYTLRELKLSKVGQGNTERTV 415 E YWP V + + + + L + V Sbjct: 432 EDEFV----YWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQD-DYVLEV 486 Query: 416 WQYHFRTWPDHGVP-SDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDI 474 + WP+ P S +++ ++E E++ GP +VH G G + Sbjct: 487 RHFQCPKWPNPDAPISSTFELINVIKE-----EALTRDGPTIVHDEYGAVSAGMLCALTT 541 Query: 475 LIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQK 534 L + + +DV + +M+ R G+ QY+FIY A+ + T + Sbjct: 542 LSQQLENENA---VDVFQVAKMINLMRPGVFTDIEQYQFIYKAMLSLVSTKENGNGPMTV 598 Query: 535 SKR 537 K Sbjct: 599 DKN 601 >2C7S-A nrPDB Length = 313 Score = 394 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 123/298 (41%), Positives = 173/298 (58%), Gaps = 22/298 (7%) Query: 236 LAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDG 295 L +T+D GF EE+E+ + + S ++ +N+ KNRY NI+ +DH+RV+L Sbjct: 37 LMKTSDS--YGFKEEYESFFEGQSA---SWDVAKKDQNRAKNRYGNIIAYDHSRVILQPV 91 Query: 296 DPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVM 355 + ++P SDYINAN I + + YIATQG + TV DFWRM++QE S IVM Sbjct: 92 E-DDPSSDYINANYI--------DGYQRPSHYIATQGPVHETVYDFWRMIWQEQSACIVM 142 Query: 356 TTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTV 415 T VE G+ KC KYWPD+ + YG +V V+ +Y +R L + G N R V Sbjct: 143 VTNLVEVGRVKCYKYWPDDTEV--YGDFKVTCVEMEPLAEYVVRTFTLERRGY-NEIREV 199 Query: 416 WQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDIL 475 Q+HF WPDHGVP G+L F+ V K + AGP+VVHCSAG GRTG +IVIDI+ Sbjct: 200 KQFHFTGWPDHGVPYHATGLLSFIRRV--KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIM 257 Query: 476 IDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQ 533 +D+ +GV +D+ ++ +RS+R MVQTE QY FI+ A+ + I + Sbjct: 258 LDMAEREGV---VDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCE 312 >2OOQ-A nrPDB Length = 286 Score = 393 bits (1009), Expect = e-109, Method: Composition-based stats. Identities = 121/294 (41%), Positives = 174/294 (59%), Gaps = 24/294 (8%) Query: 233 LSKLAETTDKVK----QGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHT 288 ++ L + ++K GF EE+E L + + + KE EN+NKNRY NI+ +DH+ Sbjct: 6 VADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKED---ENRNKNRYGNIISYDHS 62 Query: 289 RVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQE 348 RV L D +P SDYINAN I + + YIATQG +Q TV DFWRM++QE Sbjct: 63 RVRLLVLD-GDPHSDYINANYI--------DGYHRPRHYIATQGPMQETVKDFWRMIWQE 113 Query: 349 NSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQ 408 NS IVM T VE G+ KCV+YWPD+ + YG ++V ++ +Y +R + K G Sbjct: 114 NSASIVMVTNLVEVGRVKCVRYWPDDTEV--YGDIKVTLIETEPLAEYVIRTFTVQKKGY 171 Query: 409 GNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGT 468 R + +HF +WPDHGVP G+L F+ +V K + +AGP+VVHCSAG GRTG Sbjct: 172 H-EIRELRLFHFTSWPDHGVPCYATGLLGFVRQV--KFLNPPEAGPIVVHCSAGAGRTGC 228 Query: 469 FIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYI 522 FI ID ++D+ +GV +D+ ++ +R+QR +VQTE QY F++ A+ Sbjct: 229 FIAIDTMLDMAENEGV---VDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEAC 279 >2PBN-A nrPDB Length = 313 Score = 388 bits (997), Expect = e-108, Method: Composition-based stats. Identities = 119/313 (38%), Positives = 174/313 (55%), Gaps = 30/313 (9%) Query: 236 LAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHD- 294 + E + GF E+FE +Q+ + + + ENK+KNRY NIL +DH+RV L Sbjct: 20 IGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPL 79 Query: 295 GDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIV 354 + SDYINAN + + K+YIATQG L++T DFWRM++++N+ +IV Sbjct: 80 PGKDSKHSDYINANYV--------DGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIV 131 Query: 355 MTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLREL-----KLSKVGQG 409 M T VE+G+ KC +YWP E + +EYG + V YT+R K+ K +G Sbjct: 132 MITNLVEKGRRKCDQYWPTENS-EEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKG 190 Query: 410 N-----TERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIG 464 N ER V QYH+ WPD GVP VL F+ + + GPV+VHCSAG+G Sbjct: 191 NPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVR--RSSAARMPETGPVLVHCSAGVG 248 Query: 465 RTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIET 524 RTGT+IVID ++ I++K ++V ++ +R+QR+ +VQTE QY FI+ A+ I Sbjct: 249 RTGTYIVIDSMLQQIKDKST---VNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILG 305 Query: 525 LQRRIEEEQKSKR 537 +E + S Sbjct: 306 -----KETEVSSN 313 >6D4D-A nrPDB Length = 292 Score = 387 bits (993), Expect = e-108, Method: Composition-based stats. Identities = 127/309 (41%), Positives = 171/309 (55%), Gaps = 25/309 (8%) Query: 215 PLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENK 274 P I +E +R + D KQ F EEF +L + + + ++EN+ Sbjct: 3 PKKYFPIPVEHLEEEIRIR-----SADDCKQ-FREEFNSLPSGHIQGTF--ELANKEENR 54 Query: 275 NKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCL 334 KNRY NILP DH+RV+L D P SDYINA+ I + K K +IA QG Sbjct: 55 EKNRYPNILPNDHSRVILSQLD-GIPCSDYINASYI--------DGYKEKNKFIAAQGPK 105 Query: 335 QNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAH 394 Q TVNDFWRMV+++ S IVM T ER + KC +YWPD YG +RV Sbjct: 106 QETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD-QGCWTYGNIRVCVEDCVVLV 164 Query: 395 DYTLRELKLSKVGQ--GNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDA 452 DYT+R+ + R V Q HF +WPD GVP P G+L FL++V K + + A Sbjct: 165 DYTIRKFCIQPQLPDGCKAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKV--KTLNPVHA 222 Query: 453 GPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYR 512 GP+VVHCSAG+GRTGTFIVID ++ ++ + +DV + + +R+QR MVQT+ QY Sbjct: 223 GPIVVHCSAGVGRTGTFIVIDAMMAMMHAE---QKVDVFEFVSRIRNQRPQMVQTDMQYT 279 Query: 513 FIYMAVQHY 521 FIY A+ Y Sbjct: 280 FIYQALLEY 288 >2JJD-A nrPDB Length = 599 Score = 385 bits (988), Expect = e-107, Method: Composition-based stats. Identities = 127/309 (41%), Positives = 171/309 (55%), Gaps = 25/309 (8%) Query: 215 PLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENK 274 P I +E +R + D KQ F EEF +L + + + ++EN+ Sbjct: 4 PKKYFPIPVEHLEEEIRIR-----SADDCKQ-FREEFNSLPSGHIQGTF--ELANKEENR 55 Query: 275 NKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCL 334 KNRY NILP DH+RV+L D P SDYINA+ I + K K +IA QG Sbjct: 56 EKNRYPNILPNDHSRVILSQLD-GIPCSDYINASYI--------DGYKEKNKFIAAQGPK 106 Query: 335 QNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAH 394 Q TVNDFWRMV+++ S IVM T ER + KC +YWPD YG +RV Sbjct: 107 QETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD-QGCWTYGNIRVCVEDCVVLV 165 Query: 395 DYTLRELKLSKVGQ--GNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDA 452 DYT+R+ + R V Q HF +WPD GVP P G+L FL++V K + + A Sbjct: 166 DYTIRKFCIQPQLPDGCKAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKV--KTLNPVHA 223 Query: 453 GPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYR 512 GP+VVHCSAG+GRTGTFIVID ++ ++ + +DV + + +R+QR MVQT+ QY Sbjct: 224 GPIVVHCSAGVGRTGTFIVIDAMMAMMHAE---QKVDVFEFVSRIRNQRPQMVQTDMQYT 280 Query: 513 FIYMAVQHY 521 FIY A+ Y Sbjct: 281 FIYQALLEY 289 Score = 355 bits (910), Expect = 5e-98, Method: Composition-based stats. Identities = 101/311 (32%), Positives = 168/311 (54%), Gaps = 21/311 (6%) Query: 219 TRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNR 278 T ++ + +E ++ + DK+ G EEF L + + + G N K R Sbjct: 295 TELDVSSLEKHLQTMHGTTTHFDKI--GLEEEFRKLTNVRI-MKENMRTGNLPANMKKAR 351 Query: 279 YKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTV 338 I+P+D RV+L E +DYINA+ I + + K +IATQG L +TV Sbjct: 352 VIQIIPYDFNRVILSMKRGQE-YTDYINASFI--------DGYRQKDYFIATQGPLAHTV 402 Query: 339 NDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTL 398 DFWRM+++ S IVM T+ ER + KC +YWP E ++ +G + + ++ + ++ Sbjct: 403 EDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSV-THGEITIEIKNDTLSEAISI 461 Query: 399 RELKLS----KVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGP 454 R+ ++ + QG R V Q+HF WP+ G+P++ G++D + V +Q+ + P Sbjct: 462 RDFLVTLNQPQARQGEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAVQKQQQQTGNH-P 520 Query: 455 VVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFI 514 + VHCSAG GRTGTFI + +++ ++ +G+ +DV + ++ +R QR MVQT QY F Sbjct: 521 ITVHCSAGAGRTGTFIALSNILERVKAEGL---LDVFQAVKSLRLQRPHMVQTLEQYEFC 577 Query: 515 YMAVQHYIETL 525 Y VQ +I+ Sbjct: 578 YKVVQDFIDIF 588 >4BPC-A nrPDB Length = 582 Score = 384 bits (985), Expect = e-107, Method: Composition-based stats. Identities = 113/315 (35%), Positives = 174/315 (55%), Gaps = 28/315 (8%) Query: 233 LSKLAETTDKVKQG----FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHT 288 ++ +AE T+++K +E+E++ + ++ + + NK KNRY N++ +DH+ Sbjct: 9 IADMAEHTERLKANDSLKLSQEYESIDPGQ---QFTWEHSNLEVNKPKNRYANVIAYDHS 65 Query: 289 RVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQE 348 RV+L + SDYINAN + + + + +YIATQG L T DFWRMV+++ Sbjct: 66 RVILQPIE-GIMGSDYINANYV--------DGYRRQNAYIATQGPLPETFGDFWRMVWEQ 116 Query: 349 NSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQ 408 S IVM T+ E+ + KC +YWP+ + YG ++V + + +R L K G Sbjct: 117 RSATIVMMTRLEEKSRIKCDQYWPN-RGTETYGFIQVTLLDTIELATFAVRTFSLHKNG- 174 Query: 409 GNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGT 468 + +R V Q+ F WPDHGVP P L FL V K + DAGP+VVHCSAG+GRTG Sbjct: 175 SSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRV--KTANPPDAGPIVVHCSAGVGRTGA 232 Query: 469 FIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRR 528 FIVID +++ I+ + +DV + ++RSQR+ MVQTE QY FI+ A+ + Sbjct: 233 FIVIDAMLERIKPEKT---VDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGA---- 285 Query: 529 IEEEQKSKRKGHEYT 543 + R + Y Sbjct: 286 -GNTEVPARSLYAYI 299 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 111/280 (39%), Positives = 158/280 (56%), Gaps = 15/280 (5%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYI 305 G EF+ L + NK KNR NI+P++ TRV L E SDYI Sbjct: 313 GMELEFKRLANSKAH-TSRFISANLPANKFKNRLVNIMPYESTRVALQPIRGVEG-SDYI 370 Query: 306 NANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKS 365 NA+ I + + +K+YIATQG L T DFWRM+++ NS ++VM TK E G+ Sbjct: 371 NASFI--------DGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGRE 422 Query: 366 KCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPD 425 KC +YWP E + + Y V + E Y LRE K++ G RTV Q+ F WP+ Sbjct: 423 KCHQYWPAERSAR-YQYFVVDPMAEYNMPQYILREFKVTDARDGQ-SRTVRQFQFTDWPE 480 Query: 426 HGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVD 485 GVP G +DF+ +VH +E GP+ VHCSAG+GRTG FI + I+++ +R +GV Sbjct: 481 QGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGV- 539 Query: 486 CDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETL 525 +D+ +T++M+R+QR MVQTE +Y+F Y A Y+ + Sbjct: 540 --VDIFQTVKMLRTQRPAMVQTEDEYQFAYQAALEYLGSF 577 >2NV5-A nrPDB Length = 299 Score = 383 bits (983), Expect = e-106, Method: Composition-based stats. Identities = 110/295 (37%), Positives = 171/295 (57%), Gaps = 23/295 (7%) Query: 233 LSKLAETTDKVKQG----FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHT 288 + +LA+ +++K F +E+E++ + ++ + + NK KNRY N++ +DH+ Sbjct: 11 ILELADHIERLKANDNLKFSQEYESIDPGQ---QFTWEHSNLEVNKPKNRYANVIAYDHS 67 Query: 289 RVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQE 348 RV+L + P SDY+NAN I + + + +YIATQG L T DFWRM++++ Sbjct: 68 RVLLSAIE-GIPGSDYVNANYI--------DGYRKQNAYIATQGSLPETFGDFWRMIWEQ 118 Query: 349 NSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQ 408 S +VM TK ER + KC +YWP + +G+++V + Y +R L K G Sbjct: 119 RSATVVMMTKLEERSRVKCDQYWPS-RGTETHGLVQVTLLDTVELATYCVRTFALYKNG- 176 Query: 409 GNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGT 468 + +R V Q+ F WPDHGVP P L FL V K + DAGP+VVHCSAG+GRTG Sbjct: 177 SSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRV--KTCNPPDAGPMVVHCSAGVGRTGC 234 Query: 469 FIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE 523 FIVID +++ I+ + +D+ + ++R+QR+ MVQTE QY FI+ A+ + Sbjct: 235 FIVIDAMLERIKHEKT---VDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVT 286 >1LAR-A nrPDB Length = 575 Score = 382 bits (982), Expect = e-106, Method: Composition-based stats. Identities = 110/292 (37%), Positives = 172/292 (58%), Gaps = 23/292 (7%) Query: 233 LSKLAETTDKVKQG----FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHT 288 ++ LA+ +++K F +E+E++ + ++ + + NK KNRY N++ +DH+ Sbjct: 2 ITDLADNIERLKANDGLKFSQEYESIDPGQ---QFTWENSNLEVNKPKNRYANVIAYDHS 58 Query: 289 RVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQE 348 RV+L D P SDYINAN I + + + +YIATQG L T+ DFWRMV+++ Sbjct: 59 RVILTSID-GVPGSDYINANYI--------DGYRKQNAYIATQGPLPETMGDFWRMVWEQ 109 Query: 349 NSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQ 408 + +VM T+ E+ + KC +YWP + G+++V + YT+R L K G Sbjct: 110 RTATVVMMTRLEEKSRVKCDQYWPA-RGTETCGLIQVTLLDTVELATYTVRTFALHKSG- 167 Query: 409 GNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGT 468 + +R + Q+ F WPDHGVP P +L FL V K + +DAGP+VVHCSAG+GRTG Sbjct: 168 SSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRV--KACNPLDAGPMVVHCSAGVGRTGC 225 Query: 469 FIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQH 520 FIVID +++ ++ + +D+ + +RSQR+ MVQTE QY FI+ A+ Sbjct: 226 FIVIDAMLERMKHEKT---VDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE 274 Score = 358 bits (920), Expect = 3e-99, Method: Composition-based stats. Identities = 110/309 (35%), Positives = 167/309 (54%), Gaps = 21/309 (6%) Query: 219 TRINAAEIESRVRELSKL--AETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNK 276 T + A + + +++L ++ E+ ++ F L NK K Sbjct: 281 TEVPARNLYAHIQKLGQVPPGESVTAMELEF-----KLLASSKAHTSRFISANLPCNKFK 335 Query: 277 NRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQN 336 NR NI+P++ TRV L E SDYINA+ + + + +K+YIATQG L Sbjct: 336 NRLVNIMPYELTRVCLQPIRGVEG-SDYINASFL--------DGYRQQKAYIATQGPLAE 386 Query: 337 TVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDY 396 + DFWRM+++ NS +IVM TK E G+ KC +YWP E + + Y V + E Y Sbjct: 387 STEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSAR-YQYFVVDPMAEYNMPQY 445 Query: 397 TLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVV 456 LRE K++ G RT+ Q+ F WP+ GVP G +DF+ +VH +E GP+ Sbjct: 446 ILREFKVTDARDGQ-SRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPIT 504 Query: 457 VHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYM 516 VHCSAG+GRTG FI + I+++ +R +GV +D+ +T++ +R+QR MVQTE QY+ Y Sbjct: 505 VHCSAGVGRTGVFITLSIVLERMRYEGV---VDMFQTVKTLRTQRPAMVQTEDQYQLCYR 561 Query: 517 AVQHYIETL 525 A Y+ + Sbjct: 562 AALEYLGSF 570 >3I36-A nrPDB Length = 342 Score = 379 bits (972), Expect = e-105, Method: Composition-based stats. Identities = 110/281 (39%), Positives = 156/281 (55%), Gaps = 17/281 (6%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYI 305 GF EE+E L+ L + + EN+ KNRY N+LP+D +RV L + DYI Sbjct: 45 GFAEEYEDLKLIGISL--PKYAAEIAENRGKNRYNNVLPYDISRVKLSVQTHSTD--DYI 100 Query: 306 NANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKS 365 NAN + KK +IATQG L NT+ DFWRMV+++N IVM TK VE+G++ Sbjct: 101 NANYM--------PGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQGRT 152 Query: 366 KCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPD 425 KC +YWP + A ++YG + V E ++T+R+ + + Q + + Q+HF +WPD Sbjct: 153 KCEEYWPSKQA-QDYGDITVAMTSEVVLPEWTIRDFVVKNM-QSSESHPLRQFHFTSWPD 210 Query: 426 HGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVD 485 HGVP +++F V + I P++VHCSAG+GRTGTFI ID LI I + Sbjct: 211 HGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENT- 269 Query: 486 CDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQ 526 +DV + +R R MVQTE QY F+ V I + Sbjct: 270 --VDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIRAQK 308 >1RPM-A nrPDB Length = 278 Score = 377 bits (969), Expect = e-105, Method: Composition-based stats. Identities = 116/294 (39%), Positives = 167/294 (56%), Gaps = 24/294 (8%) Query: 233 LSKLAETTDKVK----QGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHT 288 ++ L + ++K GF EE+E+ + + ++ EN+ KNRY NI+ +DH+ Sbjct: 4 VADLLQHITQMKCAEGYGFKEEYESFFEGQSA---PWDSAKKDENRMKNRYGNIIAYDHS 60 Query: 289 RVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQE 348 RV L + + SDYIN N I + YIATQG +Q T+ DFWRMV+ E Sbjct: 61 RVRLQTIEGDT-NSDYINGNYI--------DGYHRPNHYIATQGPMQETIYDFWRMVWHE 111 Query: 349 NSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQ 408 N+ I+M T VE G+ KC KYWPD+ + Y ++V ++ +Y +R + K G Sbjct: 112 NTASIIMVTNLVEVGRVKCCKYWPDDTEI--YKDIKVTLIETELLAEYVIRTFAVEKRGV 169 Query: 409 GNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGT 468 R + Q+HF WPDHGVP G+L F+ +V K S AGP+VVHCSAG GRTG Sbjct: 170 H-EIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSK--SPPSAGPLVVHCSAGAGRTGC 226 Query: 469 FIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYI 522 FIVIDI++D+ +GV +D+ ++ +RS+R MVQTE QY FI+ A+ Sbjct: 227 FIVIDIMLDMAEREGV---VDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC 277 >2H03-A nrPDB Length = 291 Score = 377 bits (967), Expect = e-104, Method: Composition-based stats. Identities = 102/292 (34%), Positives = 152/292 (52%), Gaps = 19/292 (6%) Query: 237 AETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGD 296 + +E+E L+ + S EN+ KNRY NILP+D TRV L Sbjct: 19 MKLQADSNYLLSKEYEELK--DVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLS--- 73 Query: 297 PNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMT 356 SDYINA+ I + ++ YI TQG L T +DFW+MV+++N IVM Sbjct: 74 ---GGSDYINASYI--------PGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMV 122 Query: 357 TKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVW 416 T+ VE+G+ KC YWP + YG + ++ + ES ++T+RE K+ Q + R + Sbjct: 123 TQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIR 182 Query: 417 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 +H+ WPDHGVP ++ F+ V AGP VVHCSAG+GRTGTFI +D ++ Sbjct: 183 HFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRIL 242 Query: 477 DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRR 528 + K +D+ + +R R MVQTE QY +++ V+ + + R Sbjct: 243 QQLDSKD---SVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLR 291 >1YFO-A nrPDB Length = 302 Score = 376 bits (966), Expect = e-104, Method: Composition-based stats. Identities = 120/310 (38%), Positives = 174/310 (56%), Gaps = 23/310 (7%) Query: 214 QPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQEN 273 P + ++ E+++ +K+ F EEF L + + ++EN Sbjct: 1 SPSTNRKYPPLPVDKLEEEINRRMADDNKL---FREEFNALPACPI--QATCEAASKEEN 55 Query: 274 KNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGC 333 K KNRY NILP+DH+RV L + P SDYINA+ I N + K +IA QG Sbjct: 56 KEKNRYVNILPYDHSRVHLTPVE-GVPDSDYINASFI--------NGYQEKNKFIAAQGP 106 Query: 334 LQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAA 393 + TVNDFWRM++++N+ IVM T ER + KC +YWPD YG +RV + Sbjct: 107 KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD-QGCWTYGNVRVSVEDVTVL 165 Query: 394 HDYTLRELKLSKVGQ---GNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIM 450 DYT+R+ + +VG +R + Q+HF +WPD GVP P G+L FL++V K + Sbjct: 166 VDYTVRKFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV--KACNPQ 223 Query: 451 DAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ 510 AG +VVHCSAG+GRTGTF+VID ++D++ + +DV + +R+QR MVQT+ Q Sbjct: 224 YAGAIVVHCSAGVGRTGTFVVIDAMLDMMHSE---RKVDVYGFVSRIRAQRCQMVQTDMQ 280 Query: 511 YRFIYMAVQH 520 Y FIY A+ Sbjct: 281 YVFIYQALLE 290 >5AWX-A nrPDB Length = 298 Score = 374 bits (960), Expect = e-104, Method: Composition-based stats. Identities = 111/285 (38%), Positives = 164/285 (57%), Gaps = 22/285 (7%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVL-HDGDPNEPVSDY 304 GF EEFE +Q L + +NK+KNRY NI+ +DH+RV L + + ++DY Sbjct: 21 GFTEEFEEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQLAEKDGKLTDY 80 Query: 305 INANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGK 364 INAN + + K+YIA QG L++T DFWRM+++ N VIVM T VE+G+ Sbjct: 81 INANYV--------DGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGR 132 Query: 365 SKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKL--SKVGQGNTE-----RTVWQ 417 KC +YWP + +EYG V YT+R L +K+ +G+ + R V Q Sbjct: 133 RKCDQYWPAD-GSEEYGNFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVTQ 191 Query: 418 YHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 477 YH+ WPD GVP VL F+ + + + + GPVVVHCSAG+GRTGT+IV+D ++ Sbjct: 192 YHYTQWPDMGVPEYSLPVLTFVRKAAYAKRHAV--GPVVVHCSAGVGRTGTYIVLDSMLQ 249 Query: 478 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYI 522 I+ +G +++ ++ +RSQR+ +VQTE QY FI+ + I Sbjct: 250 QIQHEGT---VNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAI 291 >2CFV-A nrPDB Length = 316 Score = 372 bits (955), Expect = e-103, Method: Composition-based stats. Identities = 105/281 (37%), Positives = 155/281 (55%), Gaps = 17/281 (6%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYI 305 GF EE+E L+ + + + EN+ KNRY N+LP+D +RV L + DYI Sbjct: 45 GFAEEYEDLKL--VGISQPKYAAELAENRGKNRYNNVLPYDISRVKLSVQTHSTD--DYI 100 Query: 306 NANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKS 365 NAN + KK +IATQG L NT+ DFWRMV+++N I+M TK VE+G++ Sbjct: 101 NANYM--------PGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRT 152 Query: 366 KCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPD 425 KC +YWP + A ++YG + V E ++T+R+ + + Q + + Q+HF + PD Sbjct: 153 KCEEYWPSKQA-QDYGDITVAMTSEIVLPEWTIRDFTVKNI-QTSESHPLRQFHFTSAPD 210 Query: 426 HGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVD 485 HGVP +++F V + P++VHCSAG+GRTGTFI ID LI I + Sbjct: 211 HGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENT- 269 Query: 486 CDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQ 526 +DV + +R R MVQTE QY F+ V + + + Sbjct: 270 --VDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIVRSQK 308 >3S3F-A nrPDB Length = 307 Score = 364 bits (933), Expect = e-101, Method: Composition-based stats. Identities = 104/309 (33%), Positives = 161/309 (52%), Gaps = 23/309 (7%) Query: 223 AAEIESRVRELSKLAETTDKVKQG----FWEEFETLQQQECKLLYSRKEGQRQENKNKNR 278 + + SR + AE + F EEFE L+ N+ KNR Sbjct: 18 GSHMASRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVGRD--QPCTFADLPCNRPKNR 75 Query: 279 YKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTV 338 + NILP+DH+R L D +E SDYINAN + + +I TQG L +T Sbjct: 76 FTNILPYDHSRFKLQPVDDDEG-SDYINANYV--------PGHNSPREFIVTQGPLHSTR 126 Query: 339 NDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTL 398 +DFWRM ++ NSR IVM T+ E+G+ KC +YWP++ YG ++V+ + +S D+ + Sbjct: 127 DDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFYGDIKVQILNDSHYADWVM 186 Query: 399 RELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVH 458 E L + G+ +R + +HF TWPD GVP+ P ++ F+ + + + P+VVH Sbjct: 187 TEFMLCR---GSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGA--EQRPIVVH 241 Query: 459 CSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 CSAG+GR+GTFI +D ++ I +D+ + +R +R MVQTE QY I+ + Sbjct: 242 CSAGVGRSGTFITLDRILQQINTSDY---VDIFGIVYAMRKERVWMVQTEQQYICIHQCL 298 Query: 519 QHYIETLQR 527 +E + Sbjct: 299 LAVLEGKEN 307 >2PI7-A nrPDB Length = 312 Score = 362 bits (930), Expect = e-100, Method: Composition-based stats. Identities = 106/296 (35%), Positives = 154/296 (52%), Gaps = 21/296 (7%) Query: 236 LAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDG 295 + + F +FE L+ L N+ KNRY NILP+D +RV L Sbjct: 23 IKDMAKDSDYKFSLQFEELKL--IGLDIPHFAADLPMNRCKNRYTNILPYDFSRVRLVSM 80 Query: 296 DPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVM 355 + E SDYINAN I + YIATQG L T NDFW+MV Q+ S++IVM Sbjct: 81 NEEEG-SDYINANYI--------PGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVM 131 Query: 356 TTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTV 415 T+ E+ + KC YWP YG + V + E D+ R ++S + + V Sbjct: 132 LTQCNEKRRVKCDHYWPFTEDPIAYGDITVEMLSEEEHTDWVYRNFRIS---YADEVQDV 188 Query: 416 WQYHFRTWPDHGVP--SDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVID 473 +++ WPDHGVP + +L F++ V Q+S+ GP+++HCSAG+GRTGTFI +D Sbjct: 189 MHFNYTAWPDHGVPTANAAESILQFVQMVR--QKSVKSKGPMIIHCSAGVGRTGTFIALD 246 Query: 474 ILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRI 529 L+ IR+ +D+ + +RS R MVQTE QY FI+ VQ + +++ Sbjct: 247 WLLQHIRDHEF---VDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQKKKQQF 299 >2GJT-A nrPDB Length = 295 Score = 359 bits (922), Expect = 2e-99, Method: Composition-based stats. Identities = 106/311 (34%), Positives = 159/311 (51%), Gaps = 24/311 (7%) Query: 221 INAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYK 280 +N +++ + +A+ +D F +FE L+ L N+ KNRY Sbjct: 2 MNPVQLDDFDAYIKDMAKDSD---YKFSLQFEELKL--IGLDIPHFAADLPLNRCKNRYT 56 Query: 281 NILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVND 340 NILP+D +RV L + E +DYINAN I + YIATQG L T ND Sbjct: 57 NILPYDFSRVRLVSMNEEEG-ADYINANYI--------PGYNSPQEYIATQGPLPETRND 107 Query: 341 FWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRE 400 FW+MV Q+ S++IVM T+ E+ + KC YWP YG + V + E D+ R Sbjct: 108 FWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRH 167 Query: 401 LKLSKVGQGNTERTVWQYHFRTWPDHGVP--SDPGGVLDFLEEVHHKQESIMDAGPVVVH 458 ++ + + V +++ WPDHGVP + +L F+ V Q++ GP+++H Sbjct: 168 F---RINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVR--QQATKSKGPMIIH 222 Query: 459 CSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 CSAG+GRTGTFI +D L+ IR+ +D+ + +RS R MVQTE QY FI+ V Sbjct: 223 CSAGVGRTGTFIALDRLLQHIRDHEF---VDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 279 Query: 519 QHYIETLQRRI 529 Q +++ Sbjct: 280 QLMWMKKKQQF 290 >2I75-A nrPDB Length = 320 Score = 358 bits (919), Expect = 3e-99, Method: Composition-based stats. Identities = 106/314 (33%), Positives = 164/314 (52%), Gaps = 23/314 (7%) Query: 210 LQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQ 269 + K PL++ + + + +L++ T + Q F+ L +++ + S + Sbjct: 15 IPEKAPLDSVHQDDHSLRESMIQLAEGLITGTVLTQ-----FDQLYRKKPGMTMSC--AK 67 Query: 270 RQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIA 329 +N +KNRY++I P+D TRV+L + DYINAN I E + S YIA Sbjct: 68 LPQNISKNRYRDISPYDATRVILKGNE------DYINANYINMEIPS----SSIINQYIA 117 Query: 330 TQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVK 389 QG L +T DFW+M +++ S ++VM T +VERG+ KC +YWP+ YG +V Sbjct: 118 CQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPTGSSSYGCYQVTCHS 177 Query: 390 ESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESI 449 E Y R++ L + N R + Q + WPDHGVP D LDF+ V +K+ Sbjct: 178 EEGNTAYIFRKMTLFN-QEKNESRPLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNKRAG- 235 Query: 450 MDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEA 509 PVVVHCSAGIGRTG I ++ + +I +D+ ++ +R QR+ M+QT + Sbjct: 236 -KEEPVVVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDI---VRTMRDQRAMMIQTPS 291 Query: 510 QYRFIYMAVQHYIE 523 QYRF+ A+ E Sbjct: 292 QYRFVCEAILKVYE 305 >2I1Y-A nrPDB Length = 301 Score = 357 bits (915), Expect = 1e-98, Method: Composition-based stats. Identities = 109/324 (33%), Positives = 169/324 (52%), Gaps = 27/324 (8%) Query: 209 VLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEG 268 Q ++T + A +E +R +LA+ W+ Q + ++ EG Sbjct: 4 PAQANMDISTGHMILAYMEDHLRNRDRLAKE--------WQALCAYQAEPNTCATAQGEG 55 Query: 269 QRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYI 328 N KNR+ + LP+DH R+ L + + SDYINA+ I + +YI Sbjct: 56 ----NIKKNRHPDFLPYDHARIKLK-VESSPSRSDYINASPI-------IEHDPRMPAYI 103 Query: 329 ATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNV 388 ATQG L +T+ DFW+MV++ VIVM T VE G +C +YWPDE A Y V V V Sbjct: 104 ATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGASL-YHVYEVNLV 162 Query: 389 KES-AAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQE 447 E D+ +R L V Q RT+ Q+HF +WP G P+ +LDF +V+ Sbjct: 163 SEHIWCEDFLVRSFYLKNV-QTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYR 221 Query: 448 SIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQT 507 + P++VHCS G GRTGT+I+ID++++ + KGV +ID+ T++ VR QR G+V++ Sbjct: 222 G--RSCPIIVHCSDGAGRTGTYILIDMVLNRM-AKGVK-EIDIAATLEHVRDQRPGLVRS 277 Query: 508 EAQYRFIYMAVQHYIETLQRRIEE 531 + Q+ F AV + + + + + Sbjct: 278 KDQFEFALTAVAEEVNAILKALPQ 301 >3OLR-A nrPDB Length = 313 Score = 355 bits (911), Expect = 3e-98, Method: Composition-based stats. Identities = 106/316 (33%), Positives = 169/316 (53%), Gaps = 22/316 (6%) Query: 219 TRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKL----LYSRKEGQRQENK 274 + + + + +++ A++ K+ F EF L++Q K Y ++ +N Sbjct: 15 SHMASMDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNI 74 Query: 275 NKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCL 334 KNRYK+ILP+D++RV L +E S YINAN I K+YIATQG L Sbjct: 75 KKNRYKDILPYDYSRVELSLITSDEDSS-YINANFIK--------GVYGPKAYIATQGPL 125 Query: 335 QNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALK-EYGVMRVRNVKESAA 393 T+ DFWRM+++ + +IVM E E GK KC +YW + ++ E+G V E Sbjct: 126 STTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRK 185 Query: 394 HDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAG 453 DY +R LK+ + RT++Q+H++ WPDH VPS +L+ + +V QE D+ Sbjct: 186 SDYIIRTLKVKFN---SETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQED--DSV 240 Query: 454 PVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRF 513 P+ +H SAG GRTG ID ++++ + + V I+ +R+QR +VQT+ QY Sbjct: 241 PICIHSSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYEL 300 Query: 514 IYMAVQHYIETLQRRI 529 +Y AV +E +R++ Sbjct: 301 VYNAV---LELFKRQM 313 >1WCH-A nrPDB Length = 315 Score = 353 bits (907), Expect = 8e-98, Method: Composition-based stats. Identities = 121/326 (37%), Positives = 170/326 (52%), Gaps = 29/326 (8%) Query: 208 TVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKE 267 VL + + L + + A ++S +R L L + K E E LQ E K L Sbjct: 17 AVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK-----ELENLQ--ELKPLDQCLI 69 Query: 268 GQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSY 327 GQ +EN+ KNRYKNILP+D TRV L D YINA+ I K K + Y Sbjct: 70 GQTKENRRKNRYKNILPYDATRVPLGDEGG------YINASFI------KIPVGKEEFVY 117 Query: 328 IATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGV--MRV 385 IA QG L TV DFW+M++++ S VI M T+EVE K KC +YWP+ +R+ Sbjct: 118 IACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRL 177 Query: 386 RNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHK 445 V+ + +R + L + Q R + +F WPDH PS P +L F+ + H Sbjct: 178 ALVRMQQLKGFVVRAMTLEDI-QTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHI 236 Query: 446 QESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMV 505 S GP++ HCSAGIGR+GT I ID+++ +I + D D D+ ++ +R QR GMV Sbjct: 237 HRS----GPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFDISDLVRCMRLQRHGMV 289 Query: 506 QTEAQYRFIYMAVQHYIETLQRRIEE 531 QTE QY F Y + + + LQ E+ Sbjct: 290 QTEDQYIFCYQVILYVLTRLQAEEEQ 315 >2QEP-A nrPDB Length = 304 Score = 353 bits (906), Expect = 1e-97, Method: Composition-based stats. Identities = 108/320 (33%), Positives = 166/320 (51%), Gaps = 27/320 (8%) Query: 209 VLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEG 268 +Q ++T + + +E ++ ++L + WE Q + S Sbjct: 5 PVQSNMDISTGHMILSYMEDHLKNKNRLEKE--------WEALCAYQAEPN----SSFVA 52 Query: 269 QRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYI 328 QR+EN KNR +L +DH+RV+L + + SDYINA+ IM ++ +YI Sbjct: 53 QREENVPKNRSLAVLTYDHSRVLLK-AENSHSHSDYINASPIM-------DHDPRNPAYI 104 Query: 329 ATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNV 388 ATQG L TV DFW+MV++ VIVM T E G +C YWPDE Y + V V Sbjct: 105 ATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDE-GSNLYHIYEVNLV 163 Query: 389 KES-AAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQE 447 E D+ +R L + Q N RTV Q+HF +W D GVPS +LDF +V+ Sbjct: 164 SEHIWCEDFLVRSFYLKNL-QTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYR 222 Query: 448 SIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQT 507 + P++VHCS G GR+GT+++ID++++ + + +ID+ T++ +R QR GMVQT Sbjct: 223 G--RSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKG--AKEIDIAATLEHLRDQRPGMVQT 278 Query: 508 EAQYRFIYMAVQHYIETLQR 527 + Q+ F AV + + Sbjct: 279 KEQFEFALTAVAEEVNAILA 298 >4IKC-A nrPDB Length = 281 Score = 352 bits (902), Expect = 3e-97, Method: Composition-based stats. Identities = 98/291 (33%), Positives = 153/291 (52%), Gaps = 20/291 (6%) Query: 233 LSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVL 292 L + E F EEF L + L S + N+ KNR+ NI P+++ RV L Sbjct: 10 LQHVEELCTNNNLKFQEEFSELPKFLQDL--SSTDADLPWNRAKNRFPNIKPYNNNRVKL 67 Query: 293 HDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRV 352 D + P SDYINA+ I +IATQG L TV DFWRMV++ ++ Sbjct: 68 I-ADASVPGSDYINASYIS--------GYLCPNEFIATQGPLPGTVGDFWRMVWETRAKT 118 Query: 353 IVMTTKEVERGKSKCVKYWPDE-YALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNT 411 +VM T+ E+G+ +C +YWP++ + +G + + + E D+T+R+LK+ + G Sbjct: 119 LVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHGDCM- 177 Query: 412 ERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIV 471 TV Q +F WP+HGVP + ++ F++ V + D P++VH SAG+GRTG FI Sbjct: 178 --TVRQCNFTAWPEHGVPENSAPLIHFVKLVRASRAH--DTTPMIVHSSAGVGRTGVFIA 233 Query: 472 IDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYI 522 +D L I + +D+ + +RS+R MVQ AQY F++ + + Sbjct: 234 LDHLTQHINDHDF---VDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLL 281 >5HDE-A nrPDB Length = 307 Score = 348 bits (894), Expect = 3e-96, Method: Composition-based stats. Identities = 108/305 (35%), Positives = 161/305 (52%), Gaps = 20/305 (6%) Query: 225 EIESRVRELSKLAETTDKV-KQGFWEEFETLQQQECKL----LYSRKEGQRQENKNKNRY 279 EI + + + ++ D + F +F L++ K +Y G+++EN KNRY Sbjct: 11 EILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRY 70 Query: 280 KNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVN 339 K+ILPFDH+RV L P++ SDYINAN I K+Y+ATQG L NTV Sbjct: 71 KDILPFDHSRVKLTLKTPSQD-SDYINANFIK--------GVYGPKAYVATQGPLANTVI 121 Query: 340 DFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPD-EYALKEYGVMRVRNVKESAAHDYTL 398 DFWRM+++ N +IVM +E E G+ KC +YWP + ++ E A DY + Sbjct: 122 DFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFI 181 Query: 399 RELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVH 458 R L L N R ++Q+H+ WPDH VPS +LD + + QE + P+ +H Sbjct: 182 RTLLLEF---QNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEH--EDVPICIH 236 Query: 459 CSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 CSAG GRTG ID ++++ + + +V IQ +R+QR VQT+ QY ++ A+ Sbjct: 237 CSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAI 296 Query: 519 QHYIE 523 E Sbjct: 297 AQLFE 301 >1P15-A nrPDB Length = 253 Score = 347 bits (889), Expect = 1e-95, Method: Composition-based stats. Identities = 98/261 (37%), Positives = 151/261 (57%), Gaps = 15/261 (5%) Query: 265 RKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPK 324 + G N KNR I+P++ RV++ E +DY+NA+ I + + K Sbjct: 1 MRTGNLPANMKKNRVLQIIPYEFNRVII-PVKRGEENTDYVNASFI--------DGYRQK 51 Query: 325 KSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMR 384 SYIA+QG L +T+ DFWRM+++ S IVM T+ ERG+ KC +YWP + L YG + Sbjct: 52 DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD-GLVSYGDIT 110 Query: 385 VRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHH 444 V KE YT+R+L ++ + N R + Q+HF WP+ G+PSD G+++ + V Sbjct: 111 VELKKEEECESYTVRDLLVTNTRE-NKSRQIRQFHFHGWPEVGIPSDGKGMINIIAAVQK 169 Query: 445 KQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGM 504 +Q+ + P+ VHCSAG GRTGTF + +++ ++ +G+ +DV +T++ +R QR M Sbjct: 170 QQQQSGNH-PITVHCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHM 225 Query: 505 VQTEAQYRFIYMAVQHYIETL 525 VQT QY F Y VQ YI+ Sbjct: 226 VQTLEQYEFCYKVVQEYIDAF 246 >4RHG-A nrPDB Length = 306 Score = 345 bits (885), Expect = 3e-95, Method: Composition-based stats. Identities = 99/302 (32%), Positives = 157/302 (51%), Gaps = 24/302 (7%) Query: 222 NAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKN 281 NA +E + +L K E+ + Q FE L +++ L + + +N +KNRYK+ Sbjct: 23 NADTLEGSMAQLKKGLESGTVLIQ-----FEQLYRKKPGLAITF--AKLPQNLDKNRYKD 75 Query: 282 ILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDF 341 +LP+D TRV+L + DYINA+ + E YIATQG L +T F Sbjct: 76 VLPYDTTRVLLQGNE------DYINASYVNMEIPAA----NLVNKYIATQGPLPHTCAQF 125 Query: 342 WRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLREL 401 W++V+ + +IVM T ERG++KC +YWPD + +G ++ E Y RE+ Sbjct: 126 WQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREM 185 Query: 402 KLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSA 461 ++ G E TV + WP+HGVP D L+F+ V + +D+ PV+VH SA Sbjct: 186 LVTNTQTG-EEHTVTHLQYVAWPEHGVPDDSSDFLEFVNYVRSLR---VDSEPVLVHSSA 241 Query: 462 GIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHY 521 GIGRTG + ++ + + +D+ ++ +R QR+ MVQT +QY+F+ A+ Sbjct: 242 GIGRTGVLVTMETAMCLTERNLPIYPLDI---VRKMRDQRAMMVQTSSQYKFVCEAILRV 298 Query: 522 IE 523 E Sbjct: 299 YE 300 >4BJO-A nrPDB Length = 338 Score = 341 bits (875), Expect = 4e-94, Method: Composition-based stats. Identities = 99/301 (32%), Positives = 163/301 (54%), Gaps = 27/301 (8%) Query: 223 AAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNI 282 +E+E ++ K ++ ++ + + + + +NKN+NRY+++ Sbjct: 17 GSEMEKEFEQIDKSGSWAAI--------YQDIRHEASD--FPCRVAKLPKNKNRNRYRDV 66 Query: 283 LPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFW 342 PFDH+R+ LH D +DYINA++I E + ++SYI TQG L NT FW Sbjct: 67 SPFDHSRIKLHQED-----NDYINASLIKME--------EAQRSYILTQGPLPNTCGHFW 113 Query: 343 RMVFQENSRVIVMTTKEVERGKSKCVKYWP---DEYALKEYGVMRVRNVKESAAHDYTLR 399 MV+++ SR +VM + +E+G KC +YWP ++ + E +++ + E YT+R Sbjct: 114 EMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVR 173 Query: 400 ELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHC 459 +L+L + R + +H+ TWPD GVP P L+FL +V + GPVVVHC Sbjct: 174 QLELENL-TTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHC 232 Query: 460 SAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQ 519 SAGIGR+GTF + D + ++ ++ +D+ K + +R R G++QT Q RF Y+AV Sbjct: 233 SAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVI 292 Query: 520 H 520 Sbjct: 293 E 293 >6D3F-A nrPDB Length = 279 Score = 338 bits (868), Expect = 3e-93, Method: Composition-based stats. Identities = 96/284 (33%), Positives = 155/284 (54%), Gaps = 19/284 (6%) Query: 246 GFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYI 305 G EEF L + + + G N K R I+P+D RV+L E +DYI Sbjct: 4 GLEEEFRKLTNVRI-MKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQE-YTDYI 61 Query: 306 NANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKS 365 NA+ I + + K +IATQG L +TV DFWRM+++ S IVM T+ ER + Sbjct: 62 NASFI--------DGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQD 113 Query: 366 KCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLS----KVGQGNTERTVWQYHFR 421 KC +YWP E ++ +G + + ++ + ++R+ ++ + Q R V Q+HF Sbjct: 114 KCYQYWPTEGSV-THGEITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFH 172 Query: 422 TWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIRE 481 WP+ G+P++ G++D + V +Q+ + P+ VHCSAG GRTGTFI + +++ ++ Sbjct: 173 GWPEIGIPAEGKGMIDLIAAVQKQQQQTGNH-PITVHCSAGAGRTGTFIALSNILERVKA 231 Query: 482 KGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETL 525 +G+ +DV + ++ +R QR MVQT QY F Y VQ +I+ Sbjct: 232 EGL---LDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIF 272 >4GE6-A nrPDB Length = 314 Score = 338 bits (866), Expect = 5e-93, Method: Composition-based stats. Identities = 103/308 (33%), Positives = 161/308 (52%), Gaps = 28/308 (9%) Query: 229 RVRELSKLAETTD-KVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDH 287 + +L + + + KQG +EE+E ++++ + N KNRY ++ D Sbjct: 9 HAMTIQELVDYVNARQKQGIYEEYEDIRRENPVGTFHC--SMSPGNLEKNRYGDVPCLDQ 66 Query: 288 TRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQ 347 TRV L + +DYINA+ + + K K +YI TQG L+NT DFW MV++ Sbjct: 67 TRVKLTKRSGHTQ-TDYINASFM--------DGYKQKNAYIGTQGPLENTYRDFWLMVWE 117 Query: 348 ENSRVIVMTTKEVERGKSKCVKYWPDEYALK-EYGVMRVRNVKESAAHDYTLRELKLSKV 406 + VIVMTT+ E G+ KC +YWP E + +G + V N+ + Y L++ Sbjct: 118 QKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNT 177 Query: 407 GQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMD-----------AGPV 455 + +R V + F +WPD+GVPS ++DFL V ++Q + P+ Sbjct: 178 EE-RQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPI 236 Query: 456 VVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 515 VVHCSAGIGRTGTF +DI + + E G ++V +T+ +R+QR+ +QT QY F Y Sbjct: 237 VVHCSAGIGRTGTFCSLDICLAQLEELGT---LNVFQTVSRMRTQRAFSIQTPEQYYFCY 293 Query: 516 MAVQHYIE 523 A+ + E Sbjct: 294 KAILEFAE 301 >4GFV-A nrPDB Length = 297 Score = 337 bits (863), Expect = 1e-92, Method: Composition-based stats. Identities = 103/285 (36%), Positives = 148/285 (51%), Gaps = 20/285 (7%) Query: 250 EFETLQQQ----ECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYI 305 EF +Q + + S G R EN KNRYK++LP+D TRV+L E SDYI Sbjct: 26 EFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQ-EEGHSDYI 84 Query: 306 NANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKS 365 N N I +YIATQG L +T+ DFWR+V++ +VI+M +E+E G+ Sbjct: 85 NGNFIR--------GVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRK 136 Query: 366 KCVKYWPDEYALKEYGVMRVRNVKESAA-HDYTLRELKLSKVGQGNTERTVWQYHFRTWP 424 +C +YW E + G+ + +KE D LR LK++ R+V+Q + +WP Sbjct: 137 RCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTF---QKESRSVYQLQYMSWP 193 Query: 425 DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGV 484 D GVPS P +L +EE Q S + P+ VH SAG GRTG +D + ++ + + Sbjct: 194 DRGVPSSPDHMLAMVEEARRLQGSGPE--PLCVHSSAGCGRTGVLCTVDYVRQLLLTQMI 251 Query: 485 DCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQH-YIETLQRR 528 D + + +R QR VQTE QYRF+Y V + TLQ Sbjct: 252 PPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQNA 296 >2A8B-A nrPDB Length = 283 Score = 334 bits (856), Expect = 7e-92, Method: Composition-based stats. Identities = 111/296 (37%), Positives = 155/296 (52%), Gaps = 21/296 (7%) Query: 226 IESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPF 285 I SR+ S+L + EF + KE + KNRYK ILP Sbjct: 1 IPSRILTRSQLRD-VVASSHLLQSEFMEIPMNFVDP----KEIDIPRHGTKNRYKTILPN 55 Query: 286 DHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMV 345 +RV L + + +S YINAN I S +K++IATQG + NTV+DFW+MV Sbjct: 56 PLSRVCLRPKNVTDSLSTYINANYIR-------GYSGKEKAFIATQGPMINTVDDFWQMV 108 Query: 346 FQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSK 405 +QE+S VIVM TK E+ KCV YWP++ + YG + V + + +YT+R L L Sbjct: 109 WQEDSPVIVMITKLKEKN-EKCVLYWPEKRGI--YGKVEVLVISVNECDNYTIRNLVLK- 164 Query: 406 VGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGR 465 QG+ + V Y + +WPDH P +L + +V + + GPVVVHCSAGIGR Sbjct: 165 --QGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGR 222 Query: 466 TGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHY 521 TG FI I ++E+GV +D + +R R GMVQT QY F++ A+ Y Sbjct: 223 TGCFIATSIGCQQLKEEGV---VDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLY 275 >1ZC0-A nrPDB Length = 309 Score = 330 bits (845), Expect = 2e-90, Method: Composition-based stats. Identities = 103/286 (36%), Positives = 142/286 (49%), Gaps = 25/286 (8%) Query: 247 FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYIN 306 EEF + ++ + +K+RYK ILP +RV L E DYIN Sbjct: 46 LEEEFLKIPSNFVSP----EDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDG-DYIN 100 Query: 307 ANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSK 366 AN I +K YIATQG + NTV+DFW MV+QE +IVM T+ E GK K Sbjct: 101 ANYIR-------GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEK 152 Query: 367 CVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDH 426 CV YWP E YG ++R +YT+R+L + R+V F WPDH Sbjct: 153 CVHYWPTEEE--TYGPFQIRIQDMKECPEYTVRQLTIQ---YQEERRSVKHILFSAWPDH 207 Query: 427 GVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDC 486 P G +L + EV E+ GP+VVHCSAGIGRTG FI I ++ +G Sbjct: 208 QTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG--- 264 Query: 487 DIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEE 532 ++D+ + +R R GM+QT QY+F++ + Y ++ EE Sbjct: 265 EVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAG----QLPEE 306 >1L8K-A nrPDB Length = 314 Score = 325 bits (832), Expect = 4e-89, Method: Composition-based stats. Identities = 98/287 (34%), Positives = 152/287 (52%), Gaps = 30/287 (10%) Query: 247 FWEEFETLQQQE-----------CKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDG 295 EFE L Q Y + + EN+N+NRY+++ P+DH+RV L + Sbjct: 5 IEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNA 64 Query: 296 DPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVM 355 + +DYINA+++ E + ++SYI TQG L NT FW MV+Q+ ++ +VM Sbjct: 65 E-----NDYINASLVDIE--------EAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVM 111 Query: 356 TTKEVERGKSKCVKYWPDEYALKEYGV--MRVRNVKESAAHDYTLRELKLSKVGQGNTER 413 + VE+ KC +YWP + + V+ + E YT+ L+L + G R Sbjct: 112 LNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSG-ETR 170 Query: 414 TVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVID 473 T+ +H+ TWPD GVP P L+FL +V D GP V+HCSAGIGR+GTF ++D Sbjct: 171 TISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVD 230 Query: 474 ILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQH 520 + ++ + DI++ + + +R R G++QT Q RF YMA+ Sbjct: 231 TCLVLMEKGD---DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIE 274 >2BZL-A nrPDB Length = 325 Score = 323 bits (829), Expect = 1e-88, Method: Composition-based stats. Identities = 101/325 (31%), Positives = 167/325 (51%), Gaps = 33/325 (10%) Query: 210 LQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQ 269 L + ++ TR+ ++ R R L K E + E+E + +++ ++S Sbjct: 18 LYFQSMVDATRV---PMDERFRTLKKKLEEGMV-----FTEYEQIPKKKANGIFS--TAA 67 Query: 270 RQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIA 329 EN ++R + ++P++ RV L N + YINA+ I K + YIA Sbjct: 68 LPENAERSRIREVVPYEENRVELIPTKENN--TGYINASHI------KVVVGGAEWHYIA 119 Query: 330 TQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWP---DEYALKEYGVMRVR 386 TQG L +T +DFW+MV+++ VI M T E E G++K +YWP +++ YG +V Sbjct: 120 TQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVT 179 Query: 387 NVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVH--H 444 + + Y LK+ + G RTVW + WPDHG P D G L +LEE+ Sbjct: 180 TKFRTDSVCYATTGLKVKHLLSGQE-RTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVR 238 Query: 445 KQESIMDAG------PVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR 498 + + M G P+VVHCSAG+GRTG I+ +++I + ++VP ++++R Sbjct: 239 RHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHN---EKVEVPMMLRLLR 295 Query: 499 SQRSGMVQTEAQYRFIYMAVQHYIE 523 QR M+QT AQY+F+Y + +++ Sbjct: 296 EQRMFMIQTIAQYKFVYQVLIQFLQ 320 >6H8S-A nrPDB Length = 301 Score = 313 bits (801), Expect = 2e-85, Method: Composition-based stats. Identities = 108/276 (39%), Positives = 144/276 (52%), Gaps = 21/276 (7%) Query: 247 FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYIN 306 EF + KE KNRYK ILP H+RV L DP +P+S YIN Sbjct: 38 LQAEFFEIPMNFVDP----KEYDIPGLVRKNRYKTILPNPHSRVRLTSPDPEDPLSSYIN 93 Query: 307 ANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSK 366 AN I S +K YIATQG + +TV DFWRMV+QE + +IVM T E K Sbjct: 94 ANYIR-------GYSGEEKVYIATQGPIVSTVADFWRMVWQERTPIIVMITNIEEMN-EK 145 Query: 367 CVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDH 426 C +YWP+E + + + V+ V + DY LR + L + G ERT+ Y F +WPD Sbjct: 146 CTEYWPEEQVVHDGVEITVQKVIHTE--DYRLRLISLRR---GTEERTLKHYWFTSWPDQ 200 Query: 427 GVPSDPGGVLDFLEEVHH-KQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVD 485 P +L + EV Q+ P++VHCSAGIGRTG FI I +R +GV Sbjct: 201 KTPDRAPPLLHLVREVEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATSICCQQLRREGV- 259 Query: 486 CDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHY 521 +D+ KT +R R GM+QT QY+F++ A+ Y Sbjct: 260 --VDILKTTCQLRQDRGGMIQTCEQYQFVHHAMSLY 293 >5OVR-A nrPDB Length = 305 Score = 312 bits (799), Expect = 3e-85, Method: Composition-based stats. Identities = 105/276 (38%), Positives = 140/276 (50%), Gaps = 21/276 (7%) Query: 247 FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYIN 306 EF + KE KNRYK ILP H+RV L DP++P+S YIN Sbjct: 42 LQAEFFEIPMNFVDP----KEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYIN 97 Query: 307 ANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSK 366 AN I +K YIATQG + +TV DFWRMV+QE++ +IVM T E K Sbjct: 98 ANYIR-------GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMN-EK 149 Query: 367 CVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDH 426 C +YWP+E Y + + K DY LR + L G ER + Y F +WPD Sbjct: 150 CTEYWPEEQ--VAYDGVEITVQKVIHTEDYRLRLISLK---SGTEERGLKHYWFTSWPDQ 204 Query: 427 GVPSDPGGVLDFLEEVHH-KQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVD 485 P +L + EV Q+ P++VHCSAGIGRTG FI I +R++GV Sbjct: 205 KTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGV- 263 Query: 486 CDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHY 521 +D+ KT +R R GM+QT QY+F++ + Y Sbjct: 264 --VDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY 297 >4AZ1-A nrPDB Length = 302 Score = 272 bits (695), Expect = 4e-73, Method: Composition-based stats. Identities = 82/287 (28%), Positives = 126/287 (43%), Gaps = 37/287 (12%) Query: 250 EFETLQQQECKLLYSRKEGQRQ-------ENKNKNRYKNILPFDHTRVVLHDGDPNEPVS 302 ++E +Q++ LL R+E R +N++KNRY +IL + T P Sbjct: 17 QYERVQREFSLLL--RQEDPRSISFATSLKNRHKNRYLDILANEATLYPQVTDAPGASTP 74 Query: 303 DYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVER 362 YIN N+I + ++A Q + + DF M++++ +++M TK E Sbjct: 75 YYINGNLIDLDL---------PHKFVACQAPVVQGIPDFLAMLYEKKISLVIMVTKLEEG 125 Query: 363 GKSKCVKYWPDEYALKEYGVMRVR-----NVKESAAHDYTLR-ELKLSKV-----GQGNT 411 G K +YWP+E G + V + E Y + ELK+++ Sbjct: 126 GFVKADRYWPEERGS---GSIAVSGNCGLTISEDPGKAYEVEDELKITRRYLILQRADEP 182 Query: 412 ERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIV 471 Q + WPDHG+P + L V ++ PVVVHCSAGIGRTGT I Sbjct: 183 PHKFTQVQYTGWPDHGIPQSATSLEALLTNV----KNSPTTVPVVVHCSAGIGRTGTLIG 238 Query: 472 IDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV 518 + + +G D V + +R QR GMVQ QY IY+ + Sbjct: 239 AYAALTHLE-RGTLTDTTVYDVVSAMRRQRFGMVQRMEQYFVIYLTL 284 >3M4U-A nrPDB Length = 306 Score = 272 bits (695), Expect = 4e-73, Method: Composition-based stats. Identities = 82/296 (27%), Positives = 130/296 (43%), Gaps = 28/296 (9%) Query: 236 LAETTDKVKQG-FWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVV--L 292 +A+ + + + EF LQ+QE + + N++KNRY +IL + T L Sbjct: 9 MAQLSTRAQYSRMQREFVQLQRQENPRNINFTTSLK--NRHKNRYLDILANEETIYPPVL 66 Query: 293 HDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRV 352 YIN N+I + +++A Q + V DF + ++ + Sbjct: 67 KAVGAQPGRYPYINGNLIDLDL---------PHTFVACQAPVPQGVPDFLETLSEKKVDL 117 Query: 353 IVMTTKEVERGKSKCVKYWPDEY----ALKEYGVMRVRNVKESAAHDYTLRELKLSKVG- 407 +VM TK E G K +YWP+E + E G ++ +++ A EL + + Sbjct: 118 VVMLTKLREGGVLKAERYWPEEEEDSLSFPESGHDAIKVTRDAEASYEVDAELDIVRRPL 177 Query: 408 ----QGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGI 463 G V Q + WPDHGVP + L + ++ + P++VHCSAGI Sbjct: 178 VIHVPGKPMHRVLQVQYVGWPDHGVPESAASFDELLSVI----KNCVTTSPILVHCSAGI 233 Query: 464 GRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQ 519 GRTGT I + I +G+ D V + ++ +R GMVQ QY IYM V Sbjct: 234 GRTGTLIGAYAALLHIE-RGILTDSTVYSIVAAMKQKRFGMVQRLEQYAVIYMTVL 288 >4FL3-A nrPDB Length = 635 Score = 170 bits (431), Expect = 1e-42, Method: Composition-based stats. Identities = 68/264 (25%), Positives = 105/264 (39%), Gaps = 74/264 (28%) Query: 5 RWFHPNITGVEAENLLLTRGV-DGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQN-TGDY 62 +F NIT EAE+ L+ G+ DG +L R S++ G F LSV H I+ Sbjct: 14 PFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGT 73 Query: 63 YDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN------------------- 103 Y + GG A+ A+L Y+ + E +G V LK P N Sbjct: 74 YAIAGGRTHASPADLCHYHSQ------ESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENL 127 Query: 104 ---------------------CADPTSE-----------RWFHGHLSGKEAEKLLTEKGK 131 P E WFHG +S +E+E+++ K Sbjct: 128 IREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQIVLIGSK 187 Query: 132 -HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI-RCQELKYDVGGGERFDS 189 +G FL+R ++ + G + L + + KV H I + + K + G++FD+ Sbjct: 188 TNGKFLIR-ARDNNGSYALCLLH----------EGKVLHYRIDKDKTGKLSIPEGKKFDT 236 Query: 190 LTDLVEH--YKKNPMVETLGTVLQ 211 L LVEH YK + ++ L Q Sbjct: 237 LWQLVEHYSYKADGLLRVLTVPCQ 260 Score = 99.8 bits (247), Expect = 3e-21, Method: Composition-based stats. Identities = 37/169 (21%), Positives = 66/169 (39%), Gaps = 17/169 (10%) Query: 5 RWFHPNITGVEAENL-LLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKI-QNTGDY 62 WFH I+ E+E + L+ +G FL R +N G + L + G V H +I ++ Sbjct: 167 PWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYRIDKDKTGK 225 Query: 63 YDLYGGEKFATLAELVQYYMEHHGQL-------KEKNGDVIELKYPLNCADPTSER--WF 113 + G+KF TL +LV++Y L +K G + + P S W Sbjct: 226 LSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWS 285 Query: 114 HGH-LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESN 161 G +S ++ + S +Q + + +S + + Sbjct: 286 AGGIISRIKSYSFPKPGHRKSS----PAQGNRQESTVSFNPYEPELAPW 330 >1A81-A nrPDB Length = 254 Score = 170 bits (430), Expect = 2e-42, Method: Composition-based stats. Identities = 68/264 (25%), Positives = 105/264 (39%), Gaps = 74/264 (28%) Query: 5 RWFHPNITGVEAENLLLTRGV-DGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQN-TGDY 62 +F NIT EAE+ L+ G+ DG +L R S++ G F LSV H I+ Sbjct: 6 PFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGT 65 Query: 63 YDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN------------------- 103 Y + GG A+ A+L Y+ + E +G V LK P N Sbjct: 66 YAIAGGRTHASPADLCHYHSQ------ESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENL 119 Query: 104 ---------------------CADPTSE-----------RWFHGHLSGKEAEKLLTEKGK 131 P E WFHG +S +E+E+++ K Sbjct: 120 IREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQIVLIGSK 179 Query: 132 -HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI-RCQELKYDVGGGERFDS 189 +G FL+R ++ + G + L + + KV H I + + K + G++FD+ Sbjct: 180 TNGKFLIR-ARDNNGSYALCLLH----------EGKVLHYRIDKDKTGKLSIPEGKKFDT 228 Query: 190 LTDLVEH--YKKNPMVETLGTVLQ 211 L LVEH YK + ++ L Q Sbjct: 229 LWQLVEHYSYKADGLLRVLTVPCQ 252 >2OZO-A nrPDB Length = 613 Score = 147 bits (370), Expect = 1e-35, Method: Composition-based stats. Identities = 63/296 (21%), Positives = 105/296 (35%), Gaps = 74/296 (25%) Query: 5 RWFHPNITGVEAENLLLTRGV-DGSFLARPSKSNPGDFTLSVRRNGAVTHIKI-QNTGDY 62 +F+ +I+ EAE L G+ DG FL R + G + LS+ + H I + Sbjct: 9 PFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGT 68 Query: 63 YDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN------------------- 103 Y + GG+ AEL ++Y ++ +G L+ P N Sbjct: 69 YAIAGGKAHCGPAELCEFYS------RDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAM 122 Query: 104 ---------------------CADPTSE-----------RWFHGHLSGKEAEK-LLTEKG 130 P E W+H L+ +EAE+ L + Sbjct: 123 VRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSGAQ 182 Query: 131 KHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI-RCQELKYDVGGGERFDS 189 G FL+R + G + LS+ G V H +I + + KY + G +FD+ Sbjct: 183 TDGKFLLRPRKEQ-GTYALSLIYG----------KTVYHYLISQDKAGKYCIPEGTKFDT 231 Query: 190 LTDLVEHYKK--NPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKV 243 L LVE+ K + ++ L N + A + + L+ D + Sbjct: 232 LWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTLPAHPSTLTHPQRRIDTL 287 Score = 63.5 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 43/154 (27%), Positives = 67/154 (43%), Gaps = 19/154 (12%) Query: 106 DPTSE-RWFHGHLSGKEAEKLLTEKG-KHGSFLVRESQSHPGDFVLSVRTGDDKGESNDG 163 DP + +F+G +S EAE+ L G G FL+R+ G +VLS+ Sbjct: 3 DPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVH---------- 52 Query: 164 KSKVTHVMI-RCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRIN 222 + H I R Y + GG+ +L E Y ++P G L++P N R + Sbjct: 53 DVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDP----DGLPCNLRKPCN--RPS 106 Query: 223 AAEIESRVRELSKLAETTDKVKQGFWEEFETLQQ 256 E + V + + A D V+Q + E E L+Q Sbjct: 107 GLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQ 140 >4XZ1-A nrPDB Length = 262 Score = 145 bits (365), Expect = 6e-35, Method: Composition-based stats. Identities = 61/265 (23%), Positives = 99/265 (37%), Gaps = 76/265 (28%) Query: 5 RWFHPNITGVEAENLLLTRGV-DGSFLARPSKSNPGDFTLSVRRNGAVTHIKI-QNTGDY 62 +F+ +I+ EAE L G+ DG FL R + G + LS+ + H I + Sbjct: 12 PFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGT 71 Query: 63 YDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN------------------- 103 Y + GG+ AEL ++Y ++ +G L+ P N Sbjct: 72 YAIAGGKAHCGPAELCEFYS------RDPDGLPCNLRKPCNRPSGLEPQPGVFDSLRDAM 125 Query: 104 ---------------------CADPTSE-----------RWFHGHLSGKEAEK-LLTEKG 130 P E W+H L+ +EAE+ L + Sbjct: 126 VRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSGAQ 185 Query: 131 KHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI-RCQELKYDVGGGERFDS 189 G FL+R + G + LS+ G V H +I + + KY + G +FD+ Sbjct: 186 TDGKFLLRPRKEQ-GTYALSLIYG----------KTVYHYLISQDKAGKYCIPEGTKFDT 234 Query: 190 LTDLVEHYKKNPMVETLGTVLQLKQ 214 L LVE+ K ++ G + LK+ Sbjct: 235 LWQLVEYLK----LKADGLIYCLKE 255 Score = 98.2 bits (243), Expect = 9e-21, Method: Composition-based stats. Identities = 33/100 (33%), Positives = 46/100 (46%), Gaps = 9/100 (9%) Query: 5 RWFHPNITGVEAENLLLTR-GVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKI-QNTGDY 62 W+H ++T EAE L + DG FL RP K G + LS+ V H I Q+ Sbjct: 165 PWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQ-GTYALSLIYGKTVYHYLISQDKAGK 223 Query: 63 YDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 102 Y + G KF TL +LV+Y + +G + LK Sbjct: 224 YCIPEGTKFDTLWQLVEYLKL------KADGLIYCLKEAC 257 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 43/154 (27%), Positives = 67/154 (43%), Gaps = 19/154 (12%) Query: 106 DPTSE-RWFHGHLSGKEAEKLLTEKG-KHGSFLVRESQSHPGDFVLSVRTGDDKGESNDG 163 DP + +F+G +S EAE+ L G G FL+R+ G +VLS+ Sbjct: 6 DPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVH---------- 55 Query: 164 KSKVTHVMI-RCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRIN 222 + H I R Y + GG+ +L E Y ++P G L++P N R + Sbjct: 56 DVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDP----DGLPCNLRKPCN--RPS 109 Query: 223 AAEIESRVRELSKLAETTDKVKQGFWEEFETLQQ 256 E + V + + A D V+Q + E E L+Q Sbjct: 110 GLEPQPGVFDSLRDAMVRDYVRQTWKLEGEALEQ 143 >1AD5-A nrPDB Length = 438 Score = 124 bits (311), Expect = 1e-28, Method: Composition-based stats. Identities = 41/145 (28%), Positives = 64/145 (44%), Gaps = 13/145 (8%) Query: 101 PLNCAD----PTSERWFHGHLSGKEAEKLLTEKGKH-GSFLVRESQSHPGDFVLSVRTGD 155 P N +E WF +S K+AE+ L G GSF++R+S++ G + LSVR D Sbjct: 51 PSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYD 110 Query: 156 DKGESNDGKSKVTHVMIRCQE-LKYDVGGGERFDSLTDLVEHYKK--NPMVETLGTVLQL 212 + V H IR + + + F +L +LV+HYKK + + + L Sbjct: 111 PRQGD-----TVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS 165 Query: 213 KQPLNTTRINAAEIESRVRELSKLA 237 +P +A EI +L K Sbjct: 166 SKPQKPWEKDAWEIPRESLKLEKKL 190 Score = 108 bits (270), Expect = 7e-24, Method: Composition-based stats. Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 7/108 (6%) Query: 1 MTSRRWFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSV-----RRNGAVTHI 54 + + WF I+ +AE LL G + GSF+ R S++ G ++LSV R+ V H Sbjct: 61 LETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHY 120 Query: 55 KIQNTG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 KI+ + + F+TL ELV +Y + + L +K P Sbjct: 121 KIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKP 168 >2H8H-A nrPDB Length = 535 Score = 118 bits (296), Expect = 6e-27, Method: Composition-based stats. Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 14/143 (9%) Query: 101 PLNCADPTS----ERWFHGHLSGKEAEKLLTE-KGKHGSFLVRESQSHPGDFVLSVRTGD 155 P N P+ E W+ G ++ +E+E+LL + G+FLVRES++ G + LSV D Sbjct: 135 PSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFD 194 Query: 156 DKGESNDGKSKVTHVMIRCQE-LKYDVGGGERFDSLTDLVEHYKKN--PMVETLGTVLQL 212 + N V H IR + + + +F+SL LV +Y K+ + L TV Sbjct: 195 NAKGLN-----VKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT 249 Query: 213 KQPLNTT-RINAAEIESRVRELS 234 +P +A EI L Sbjct: 250 SKPQTQGLAKDAWEIPRESLRLE 272 Score = 107 bits (268), Expect = 1e-23, Method: Composition-based stats. Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%) Query: 1 MTSRRWFHPNITGVEAENLLL-TRGVDGSFLARPSKSNPGDFTLSVR-----RNGAVTHI 54 + + W+ IT E+E LLL G+FL R S++ G + LSV + V H Sbjct: 145 IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHY 204 Query: 55 KIQNTG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 KI+ + + +F +L +LV YY +H L + V P Sbjct: 205 KIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKP 252 >6F3F-A nrPDB Length = 455 Score = 118 bits (295), Expect = 8e-27, Method: Composition-based stats. Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 14/143 (9%) Query: 101 PLNCADPTS----ERWFHGHLSGKEAEKLLTE-KGKHGSFLVRESQSHPGDFVLSVRTGD 155 P N P+ E W+ G ++ +E+E+LL + G+FLVRES++ G + LSV D Sbjct: 55 PSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFD 114 Query: 156 DKGESNDGKSKVTHVMIRCQE-LKYDVGGGERFDSLTDLVEHYKKN--PMVETLGTVLQL 212 + N V H IR + + + +F+SL LV +Y K+ + L TV Sbjct: 115 NAKGLN-----VKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT 169 Query: 213 KQPLNTT-RINAAEIESRVRELS 234 +P +A EI L Sbjct: 170 SKPQTQGLAKDAWEIPRESLRLE 192 Score = 107 bits (267), Expect = 1e-23, Method: Composition-based stats. Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%) Query: 1 MTSRRWFHPNITGVEAENLLL-TRGVDGSFLARPSKSNPGDFTLSVR-----RNGAVTHI 54 + + W+ IT E+E LLL G+FL R S++ G + LSV + V H Sbjct: 65 IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHY 124 Query: 55 KIQNTG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 KI+ + + +F +L +LV YY +H L + V P Sbjct: 125 KIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKP 172 >1K9A-A nrPDB Length = 450 Score = 117 bits (293), Expect = 1e-26, Method: Composition-based stats. Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 34/159 (21%) Query: 111 RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHV 170 WFHG ++ ++AE+LL + G FLVRES ++PGD+ L V + KV H Sbjct: 81 PWFHGKITREQAERLLY-PPETGLFLVRESTNYPGDYTLCVSC----------EGKVEHY 129 Query: 171 MIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRV 230 I K + F++L LVEHY + G +L +P Sbjct: 130 RIMYHASKLSIDEEVYFENLMQLVEHYTT----DADGLCTRLIKP--------------- 170 Query: 231 RELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQ 269 K+ E T + F+ L +E KLL + +G+ Sbjct: 171 ----KVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGE 205 Score = 114 bits (286), Expect = 9e-26, Method: Composition-based stats. Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 7/98 (7%) Query: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64 WFH IT +AE LL G FL R S + PGD+TL V G V H +I Sbjct: 81 PWFHGKITREQAERLLYPPET-GLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLS 139 Query: 65 LYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 102 + F L +LV++Y + +G L P Sbjct: 140 IDEEVYFENLMQLVEHYT------TDADGLCTRLIKPK 171 >2FO0-A nrPDB Length = 495 Score = 117 bits (293), Expect = 1e-26, Method: Composition-based stats. Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 8/102 (7%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + W+H ++ AE LL+ G++GSFL R S+S+PG ++S+R G V H +I Sbjct: 99 LEKHSWYHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 157 Query: 61 DYYDLYGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 D E +F TLAELV ++ +G + L YP Sbjct: 158 DGKLYVSSESRFNTLAELVHHHS------TVADGLITTLHYP 193 Score = 114 bits (286), Expect = 9e-26, Method: Composition-based stats. Identities = 58/237 (24%), Positives = 94/237 (39%), Gaps = 42/237 (17%) Query: 30 LARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLK 89 LA PS+++P F + + + + GEK L H+G+ Sbjct: 32 LAGPSENDPNLFVALYDF--------VASGDNTLSITKGEKLRVLG------YNHNGEWC 77 Query: 90 EKNGDVIELKYPLNCADPTS----ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPG 145 E + P N P + W+HG +S AE LL+ G +GSFLVRES+S PG Sbjct: 78 EAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLS-SGINGSFLVRESESSPG 136 Query: 146 DFVLSVRTGDDKGESNDGKSKVTHVMIRC-QELKYDVGGGERFDSLTDLVEHYKKNPMVE 204 +S+R + +V H I + K V RF++L +LV H+ + + Sbjct: 137 QRSISLRY----------EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST--VAD 184 Query: 205 TLGTVLQLKQPLN--------TTRINAAEIESRVRELSKLAETTD--KVKQGFWEEF 251 L T L P + + E+E + +V +G W+++ Sbjct: 185 GLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKY 241 >4XEY-B nrPDB Length = 408 Score = 117 bits (292), Expect = 2e-26, Method: Composition-based stats. Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 8/102 (7%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + W+H ++ AE LL+ G++GSFL R S+S+PG ++S+R G V H +I Sbjct: 7 LEKHSWYHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 65 Query: 61 DYYDLYGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 D E +F TLAELV ++ +G + L YP Sbjct: 66 DGKLYVSSESRFNTLAELVHHHS------TVADGLITTLHYP 101 Score = 109 bits (272), Expect = 4e-24, Method: Composition-based stats. Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 24/153 (15%) Query: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTH 169 W+HG +S AE LL+ G +GSFLVRES+S PG +S+R + +V H Sbjct: 10 HSWYHGPVSRNAAEYLLS-SGINGSFLVRESESSPGQRSISLRY----------EGRVYH 58 Query: 170 VMIRC-QELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLN--------TTR 220 I + K V RF++L +LV H+ + + L T L P + Sbjct: 59 YRINTASDGKLYVSSESRFNTLAELVHHHST--VADGLITTLHYPAPKRNKPTVYGVSPN 116 Query: 221 INAAEIESRVRELSKLAETTD--KVKQGFWEEF 251 + E+E + +V +G W+++ Sbjct: 117 YDKWEMERTDITMKHKLGGGQYGEVYEGVWKKY 149 >2ABL-A nrPDB Length = 163 Score = 117 bits (292), Expect = 2e-26, Method: Composition-based stats. Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 8/102 (7%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + W+H ++ AE LL+ G++GSFL R S+S+PG ++S+R G V H +I Sbjct: 67 LEKHSWYHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 125 Query: 61 DYYDLYGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 D E +F TLAELV ++ +G + L YP Sbjct: 126 DGKLYVSSESRFNTLAELVHHHS------TVADGLITTLHYP 161 Score = 112 bits (280), Expect = 5e-25, Method: Composition-based stats. Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 18/120 (15%) Query: 101 PLNCADPTS----ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDD 156 P N P + W+HG +S AE LL+ G +GSFLVRES+S PG +S+R Sbjct: 57 PSNYITPVNSLEKHSWYHGPVSRNAAEYLLS-SGINGSFLVRESESSPGQRSISLRY--- 112 Query: 157 KGESNDGKSKVTHVMIRC-QELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQP 215 + +V H I + K V RF++L +LV H+ + + L T L P Sbjct: 113 -------EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST--VADGLITTLHYPAP 163 >6AMW-A nrPDB Length = 255 Score = 116 bits (291), Expect = 2e-26, Method: Composition-based stats. Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 8/102 (7%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + W+H ++ AE LL+ G++GSFL R S+S+PG ++S+R G V H +I Sbjct: 141 LEKHSWYHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 199 Query: 61 DYYDLYGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 D E +F TLAELV ++ +G + L YP Sbjct: 200 DGKLYVSSESRFNTLAELVHHHS------TVADGLITTLHYP 235 Score = 111 bits (278), Expect = 7e-25, Method: Composition-based stats. Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 18/120 (15%) Query: 101 PLNCADPTS----ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDD 156 P N P + W+HG +S AE LL+ G +GSFLVRES+S PG +S+R Sbjct: 131 PSNYITPVNSLEKHSWYHGPVSRNAAEYLLS-SGINGSFLVRESESSPGQRSISLRY--- 186 Query: 157 KGESNDGKSKVTHVMIRC-QELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQP 215 + +V H I + K V RF++L +LV H+ + + L T L P Sbjct: 187 -------EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST--VADGLITTLHYPAP 237 >2KK6-A nrPDB Length = 116 Score = 115 bits (287), Expect = 7e-26, Method: Composition-based stats. Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 10/112 (8%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + + W+H I +EA+ LL + G FL R S PG++ LSV +G H IQ Sbjct: 14 LAEQDWYHGAIPRIEAQELLKKQ---GDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVD 70 Query: 61 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERW 112 + Y + G F+ + +L+ ++ + +K+G V+ LN P ++W Sbjct: 71 NMYR-FEGTGFSNIPQLIDHHYTTKQVITKKSGVVL-----LNPI-PKDKKW 115 Score = 92.4 bits (228), Expect = 5e-19, Method: Composition-based stats. Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 14/112 (12%) Query: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTH 169 + W+HG + EA++LL K G FLVRES PG++VLSV + + H Sbjct: 17 QDWYHGAIPRIEAQELLK---KQGDFLVRESHGKPGEYVLSVYSDGQR----------RH 63 Query: 170 VMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRI 221 +I+ + Y G F ++ L++H+ V T + + L P+ + Sbjct: 64 FIIQYVDNMYRF-EGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPIPKDKK 114 >2AUG-A nrPDB Length = 126 Score = 114 bits (286), Expect = 9e-26, Method: Composition-based stats. Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 6/95 (6%) Query: 3 SRRWFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61 S+ WFH I+ EA+ L++ +G VDG FL R S+SNP F LS+ + H +I D Sbjct: 25 SQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVED 84 Query: 62 YYDLY-----GGEKFATLAELVQYYMEHHGQLKEK 91 +++ G +F L +LV++Y + G L K Sbjct: 85 DGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCK 119 Score = 93.2 bits (230), Expect = 3e-19, Method: Composition-based stats. Identities = 36/105 (34%), Positives = 51/105 (48%), Gaps = 16/105 (15%) Query: 103 NCADPTSERWFHGHLSGKEAEKLLTEKG-KHGSFLVRESQSHPGDFVLSVRTGDDKGESN 161 + S+ WFH +S EA++L+ ++G G FLVR+SQS+P FVLS+ G Sbjct: 19 SHMIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHG------- 71 Query: 162 DGKSKVTHVMIRCQELKYDV-----GGGERFDSLTDLVEHYKKNP 201 K+ H I E ++ G RF L LVE Y+ N Sbjct: 72 ---QKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNK 113 >3T04-A nrPDB Length = 123 Score = 114 bits (285), Expect = 1e-25, Method: Composition-based stats. Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 8/102 (7%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + W+H ++ AE LL+ G++GSFL R S+S+PG ++S+R G V H +I Sbjct: 13 LEKHSWYHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 71 Query: 61 DYYDLYGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYP 101 D E +F TLAELV ++ +G + L YP Sbjct: 72 DGKLYVSSESRFNTLAELVHHHS------TVADGLITTLHYP 107 Score = 108 bits (271), Expect = 5e-24, Method: Composition-based stats. Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 18/120 (15%) Query: 101 PLNCADPTS----ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDD 156 P N P + W+HG +S AE LL+ G +GSFLVRES+S PG +S+R Sbjct: 3 PSNYITPVNSLEKHSWYHGPVSRNAAEYLLS-SGINGSFLVRESESSPGQRSISLRY--- 58 Query: 157 KGESNDGKSKVTHVMIRC-QELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQP 215 + +V H I + K V RF++L +LV H+ + + L T L P Sbjct: 59 -------EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST--VADGLITTLHYPAP 109 >1GRI-A nrPDB Length = 217 Score = 113 bits (282), Expect = 2e-25, Method: Composition-based stats. Identities = 32/91 (35%), Positives = 44/91 (48%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 M WF I +AE +L + DG+FL R S+S PGDF+LSV+ V H K+ G Sbjct: 55 MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDG 114 Query: 61 DYYDLYGGEKFATLAELVQYYMEHHGQLKEK 91 KF +L ELV Y+ ++ Sbjct: 115 AGKYFLWVVKFNSLNELVDYHRSTSVSRNQQ 145 Score = 112 bits (279), Expect = 6e-25, Method: Composition-based stats. Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 15/128 (11%) Query: 84 HHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSH 143 + +L K+G + P N + WF G + +AE++L+++ G+FL+RES+S Sbjct: 37 YKAELNGKDGFI-----PKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESA 91 Query: 144 PGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMV 203 PGDF LSV+ G+D V H + +F+SL +LV++++ + Sbjct: 92 PGDFSLSVKFGND----------VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVS 141 Query: 204 ETLGTVLQ 211 L+ Sbjct: 142 RNQQIFLR 149 >5U06-A nrPDB Length = 120 Score = 110 bits (275), Expect = 2e-24, Method: Composition-based stats. Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 6/94 (6%) Query: 3 SRRWFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61 ++ WFH I+ E++ L+ +G VDG FL R S+ NP F LS+ V H I + + Sbjct: 16 TQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEE 75 Query: 62 YYDLY-----GGEKFATLAELVQYYMEHHGQLKE 90 LY G +F L +LV+++ + G L Sbjct: 76 EGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPC 109 Score = 95.1 bits (235), Expect = 8e-20, Method: Composition-based stats. Identities = 36/105 (34%), Positives = 54/105 (51%), Gaps = 16/105 (15%) Query: 102 LNCADPTSERWFHGHLSGKEAEKLLTEKG-KHGSFLVRESQSHPGDFVLSVRTGDDKGES 160 L+ A ++ WFHG +S +E+++L+ ++G G FLVRESQ +P FVLS+ Sbjct: 9 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCH------- 61 Query: 161 NDGKSKVTHVMIRCQELKYDV-----GGGERFDSLTDLVEHYKKN 200 KV H +I E + + G RF L LVE ++ N Sbjct: 62 ---LQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLN 103 >1NRV-A nrPDB Length = 105 Score = 110 bits (274), Expect = 2e-24, Method: Composition-based stats. Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 6/95 (6%) Query: 3 SRRWFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61 ++ WFH I+ E+ ++ +G VDG FL R S+SNP F L++ + + + +I D Sbjct: 4 TQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCED 63 Query: 62 YYDLY-----GGEKFATLAELVQYYMEHHGQLKEK 91 + G KF+ L +LV +Y + G L K Sbjct: 64 DGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCK 98 Score = 81.3 bits (199), Expect = 1e-15, Method: Composition-based stats. Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 16/101 (15%) Query: 107 PTSERWFHGHLSGKEAEKLLTEKG-KHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS 165 ++ WFHG +S +E+ +++ ++G G FL+R+SQS+P FVL++ Sbjct: 2 HRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCH----------HQ 51 Query: 166 KVTHVMIRC--QELKYDV---GGGERFDSLTDLVEHYKKNP 201 K+ + I + + G +F L LV+ Y+ N Sbjct: 52 KIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNK 92 >2EOB-A nrPDB Length = 124 Score = 107 bits (266), Expect = 2e-23, Method: Composition-based stats. Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 10/118 (8%) Query: 2 TSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61 S+ W++ ++ EAE++L+ DG+FL R + + ++ R G V H +I G Sbjct: 17 ESKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREGT-DSYAITFRARGKVKHCRINRDGR 75 Query: 62 YYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSG 119 ++ L F +L ELV YY +H K + L+YP P + G SG Sbjct: 76 HFVLGTSAYFESLVELVSYYEKHALYRK------MRLRYP---VTPELLERYSGPSSG 124 Score = 82.0 bits (201), Expect = 7e-16, Method: Composition-based stats. Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 15/116 (12%) Query: 103 NCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESND 162 N S+ W++ LS EAE +L + G+FL+R+ + + ++ R Sbjct: 12 NPNPHESKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREGT-DSYAITFR---------- 60 Query: 163 GKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNT 218 + KV H I + +G F+SL +LV +Y+K+ + ++L+ P+ Sbjct: 61 ARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRK----MRLRYPVTP 112 >2PLE-A nrPDB Length = 105 Score = 107 bits (266), Expect = 2e-23, Method: Composition-based stats. Identities = 33/102 (32%), Positives = 56/102 (54%), Gaps = 8/102 (7%) Query: 2 TSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61 S+ W+H ++T +AE++L+ DG+FL R ++ P + +S R G + H ++Q G Sbjct: 7 ESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCRVQQEGQ 65 Query: 62 YYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 L G +F +L +L+ YY +H K K L+YP+N Sbjct: 66 TVML-GNSEFDSLVDLISYYEKHPLYRKMK------LRYPIN 100 Score = 94.0 bits (232), Expect = 2e-19, Method: Composition-based stats. Identities = 32/115 (27%), Positives = 59/115 (51%), Gaps = 16/115 (13%) Query: 103 NCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESND 162 + S+ W+H L+ +AE +L + G+FLVR+ + P + +S R Sbjct: 2 SPGIHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKR-NEPNSYAISFR---------- 50 Query: 163 GKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLN 217 + K+ H ++ QE + + G FDSL DL+ +Y+K+P+ ++L+ P+N Sbjct: 51 AEGKIKHCRVQ-QEGQTVMLGNSEFDSLVDLISYYEKHPLYRK----MKLRYPIN 100 >2EKX-A nrPDB Length = 110 Score = 103 bits (257), Expect = 2e-22, Method: Composition-based stats. Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 10/107 (9%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 WF G++S ++E+LL +KGK G+F+VR S S G + +S+ + ND K V H Sbjct: 13 WFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQVGMYTVSLFS----KAVNDKKGTVKHYH 67 Query: 172 IRCQ-ELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLN 217 + E K + FDS+ L+ +++ N + G + +L+ P++ Sbjct: 68 VHTNAENKLYLAENYCFDSIPKLIHYHQHN----SAGMITRLRHPVS 110 Score = 84.7 bits (208), Expect = 1e-16, Method: Composition-based stats. Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 14/110 (12%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRR------NGAVTHI 54 + WF NI+ ++E LL +G +G+F+ R S S G +T+S+ G V H Sbjct: 8 LDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQVGMYTVSLFSKAVNDKKGTVKHY 66 Query: 55 KI-QNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 + N + L F ++ +L+ Y+ + G + L++P++ Sbjct: 67 HVHTNAENKLYLAENYCFDSIPKLIHYHQHNSA------GMITRLRHPVS 110 >2CRH-A nrPDB Length = 138 Score = 99.0 bits (245), Expect = 6e-21, Method: Composition-based stats. Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 14/113 (12%) Query: 104 CADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDG 163 D + W+ G + AE +L + G+FLVR+ +F +S++ + Sbjct: 20 PQDLSVHLWYAGPMERAGAESILANR-SDGTFLVRQRVKDAAEFAISIKYNVE------- 71 Query: 164 KSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPM---VETLGTVLQLK 213 V H+ I E Y + + F LT+LVE Y++N + ++L T LQ Sbjct: 72 ---VKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFP 121 Score = 97.8 bits (242), Expect = 1e-20, Method: Composition-based stats. Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 2/109 (1%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 ++ W+ + AE++L R DG+FL R + +F +S++ N V HIKI Sbjct: 23 LSVHLWYAGPMERAGAESILANRS-DGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAE 81 Query: 61 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTS 109 Y + + F L ELV++Y ++ + K+ L++P + + Sbjct: 82 GLYRITEKKAFRGLTELVEFYQQNSLKDCFKS-LDTTLQFPFKEPEKRT 129 >2LCT-A nrPDB Length = 107 Score = 98.2 bits (243), Expect = 8e-21, Method: Composition-based stats. Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 14/112 (12%) Query: 105 ADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164 D + W+ G + AE +L + G+FLVR+ +F +S++ + Sbjct: 4 QDLSVHLWYAGPMERAGAESILANR-SDGTFLVRQRVKDAAEFAISIKYNVE-------- 54 Query: 165 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPM---VETLGTVLQLK 213 V H+ I E Y + + F LT+LVE Y++N + ++L T LQ Sbjct: 55 --VKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFP 104 Score = 98.2 bits (243), Expect = 8e-21, Method: Composition-based stats. Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 2/102 (1%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 ++ W+ + AE++L R DG+FL R + +F +S++ N V HIKI Sbjct: 6 LSVHLWYAGPMERAGAESILANRS-DGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAE 64 Query: 61 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 102 Y + + F L ELV++Y ++ + K+ L++P Sbjct: 65 GLYRITEKKAFRGLTELVEFYQQNSLKDCFKS-LDTTLQFPF 105 >4XI2-A nrPDB Length = 446 Score = 98.2 bits (243), Expect = 1e-20, Method: Composition-based stats. Identities = 30/131 (22%), Positives = 62/131 (47%), Gaps = 15/131 (11%) Query: 101 PLNCADPTSE-----RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGD 155 P N + W+ H++ +AE+LL ++GK G F+VR+S S G + +SV Sbjct: 52 PSNYITEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSV---- 106 Query: 156 DKGESNDGKSKVTHV-MIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQ 214 + + + + H + + +Y + F ++ +L+ +++ N + G + +LK Sbjct: 107 FAKSTGEPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHN----SAGLISRLKY 162 Query: 215 PLNTTRINAAE 225 P++ NA Sbjct: 163 PVSKQNKNAPS 173 Score = 97.8 bits (242), Expect = 1e-20, Method: Composition-based stats. Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 14/110 (12%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSV------RRNGAVTHI 54 + W+ ++T +AE LL G +G F+ R S S G +T+SV G + H Sbjct: 63 IEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGEPQGVIRHY 121 Query: 55 KIQNTGD-YYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 + +T Y L F+T+ EL+ Y+ + G + LKYP++ Sbjct: 122 VVCSTPQSQYYLAEKHLFSTIPELINYHQHNSA------GLISRLKYPVS 165 >2LQW-A nrPDB Length = 303 Score = 97.8 bits (242), Expect = 1e-20, Method: Composition-based stats. Identities = 52/228 (22%), Positives = 85/228 (37%), Gaps = 28/228 (12%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 W+ G +S +EA+ L + +HG FLVR+S + PGD+VLSV S+V+H + Sbjct: 14 WYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSEN----------SRVSHYI 62 Query: 172 IRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVR 231 I + G + FD L L+E YK + + T L P + + + Sbjct: 63 INSLPNRRFKIGDQEFDHLPALLEFYKIHYL---DTTTLIEPAPRYPSPPMGSVSAPNLP 119 Query: 232 ELSKLAETTDKVKQGFWEEFETLQ--QQECKLLYSRKEGQRQENKNKN-RYKNI-LPFDH 287 E + + E L + E ++ + E Q +NK+ R I +P+ Sbjct: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 Query: 288 TRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQ 335 L P+ N N + + T L Sbjct: 180 ---KLVRSSPHGKHG---NRNSNSYGIPEPAHAYAQPQ----TTTPLP 217 Score = 95.1 bits (235), Expect = 8e-20, Method: Composition-based stats. Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Query: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64 W+ ++ EA+ L G FL R S + PGD+ LSV N V+H I + + Sbjct: 13 AWYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRF 71 Query: 65 LYGGEKFATLAELVQYYMEHH 85 G ++F L L+++Y H+ Sbjct: 72 KIGDQEFDHLPALLEFYKIHY 92 >4M4Z-A nrPDB Length = 170 Score = 97.1 bits (240), Expect = 2e-20, Method: Composition-based stats. Identities = 37/117 (31%), Positives = 54/117 (46%), Gaps = 11/117 (9%) Query: 101 PLNCADPTSERWFHGHLSGKEAEKLLTEKGKHG-SFLVRESQSHPGDFVLSVRTGDDKGE 159 P S W + LS ++AE+LL G G +FL+RESQ+ G + LSVR + Sbjct: 60 PSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVR--LSRPA 117 Query: 160 SNDGKSKVTHVMIRCQELKY-DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQP 215 S D ++ H I C + + + F SL LV+HY + LK+P Sbjct: 118 SWD---RIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSE----LADDICCLLKEP 167 Score = 80.1 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 7/103 (6%) Query: 3 SRRWFHPNITGVEAENLLLTRG-VDGSFLARPSKSNPGDFTLSVRRNG-----AVTHIKI 56 S W + ++ +AE LLL G G+FL R S++ G ++LSVR + + H +I Sbjct: 68 SHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRI 127 Query: 57 QNTGDYY-DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIEL 98 + + + F +L LV +Y E + + L Sbjct: 128 HCLDNGWLYISPRLTFPSLQALVDHYSELADDICCLLKEPCVL 170 >6DR7-A nrPDB Length = 306 Score = 97.1 bits (240), Expect = 2e-20, Method: Composition-based stats. Identities = 55/253 (21%), Positives = 98/253 (38%), Gaps = 48/253 (18%) Query: 277 NRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQN 336 NR+++I T V +D +NAN I IA Q LQ+ Sbjct: 65 NRFRDIQCRRQTAVR----------AD-LNANYIQVGNTRT----------IACQYPLQS 103 Query: 337 TVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDE-YALKEYGVMRV--RNVKESAA 393 + +RM+ + + V+ + E + PD YG + V + ++ Sbjct: 104 QLESHFRMLAENRTPVLAVLASSSEIANQRFGM--PDYFRQSGTYGSITVESKMTQQVGL 161 Query: 394 HDYTLREL-KLSKVGQGNTERTVWQYHFRTWPDHGVPSD--PGGVLDFLEEVHHKQESIM 450 D + ++ L+ G +V H TWPD GVP + +++ + ++ Sbjct: 162 GDGIMADMYTLTIREAGQKTISVPVVHVTTWPDFGVPESEVTKALASLVDQTAETKRNMY 221 Query: 451 DA------------GPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR 498 ++ P V+HC AG+GRT I + + + + + V + +R Sbjct: 222 ESKGSSAVADDSKLRP-VIHCRAGVGRTAQLIG---AMCMNDSR--NSQLSVEDMVSQMR 275 Query: 499 SQRSG-MVQTEAQ 510 QR+G MVQ + Q Sbjct: 276 VQRNGIMVQKDEQ 288 >1MIL-A nrPDB Length = 104 Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 26/102 (25%), Positives = 51/102 (50%), Gaps = 5/102 (4%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + WFH ++ EAE LL ++G FL R S + PG + L+ ++G H+ + + Sbjct: 4 LRGEPWFHGKLSRREAEALL---QLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE 60 Query: 61 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 102 +F +++ L+ Y+M++H + G + L+ P+ Sbjct: 61 GVVR-TKDHRFESVSHLISYHMDNHLPII-SAGSELCLQQPV 100 Score = 89.7 bits (221), Expect = 3e-18, Method: Composition-based stats. Identities = 37/113 (32%), Positives = 59/113 (52%), Gaps = 15/113 (13%) Query: 105 ADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164 + E WFHG LS +EAE LL +G FLVRES + PG +VL TG G+ Sbjct: 2 SQLRGEPWFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVL---TGLQSGQPKHLL 55 Query: 165 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPM-VETLGTVLQLKQPL 216 ++R ++ RF+S++ L+ ++ N + + + G+ L L+QP+ Sbjct: 56 LVDPEGVVRTKD--------HRFESVSHLISYHMDNHLPIISAGSELCLQQPV 100 >2CS0-A nrPDB Length = 119 Score = 92.1 bits (227), Expect = 6e-19, Method: Composition-based stats. Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 4/83 (4%) Query: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64 WFH I+ +AENLL ++ + GSFL R S S+ G +TLS + + H ++ D Sbjct: 17 EWFHGAISREDAENLLESQPL-GSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTF 74 Query: 65 LYGGEK--FATLAELVQYYMEHH 85 + GEK +L LV ++ + Sbjct: 75 MIPGEKVAHTSLDALVTFHQQKP 97 Score = 62.0 bits (149), Expect = 7e-10, Method: Composition-based stats. Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 14/103 (13%) Query: 111 RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHV 170 WFHG +S ++AE LL + GSFL+R S SH G + LS + +S H Sbjct: 17 EWFHGAISREDAENLLESQPL-GSFLIRVSHSHVG-YTLSYK----------AQSSCCHF 64 Query: 171 MIRCQELKYDVGGGERF--DSLTDLVEHYKKNPMVETLGTVLQ 211 M++ + + GE+ SL LV +++ P+ + Q Sbjct: 65 MVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQ 107 >1KA6-A nrPDB Length = 128 Score = 90.9 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 12/108 (11%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 M + +H I+ E LLL G+DGS+L R S+S PG + L V +G + ++ T Sbjct: 1 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60 Query: 61 DYYDLYG------GEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 102 F + L+ + + G VI L+YP+ Sbjct: 61 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQ------GIVIPLQYPV 102 Score = 65.1 bits (157), Expect = 9e-11, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 44/112 (39%), Gaps = 20/112 (17%) Query: 113 FHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI 172 +HG +S + EKLL G GS+L+R+S+S PG + L V + + Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLY----------HGYIYTYRV 56 Query: 173 RCQELKYDVGG------GERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNT 218 E F + +L+ ++K G V+ L+ P+ Sbjct: 57 SQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQ----GIVIPLQYPVEK 104 >1M27-A nrPDB Length = 104 Score = 90.1 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 12/108 (11%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 M + +H I+ E LLL G+DGS+L R S+S PG + L V +G + ++ T Sbjct: 1 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60 Query: 61 DYYDLYG------GEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 102 F + L+ + + G VI L+YP+ Sbjct: 61 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQ------GIVIPLQYPV 102 Score = 64.3 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 44/112 (39%), Gaps = 20/112 (17%) Query: 113 FHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI 172 +HG +S + EKLL G GS+L+R+S+S PG + L V + + Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLY----------HGYIYTYRV 56 Query: 173 RCQELKYDVGG------GERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNT 218 E F + +L+ ++K G V+ L+ P+ Sbjct: 57 SQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQ----GIVIPLQYPVEK 104 >3RO1-A nrPDB Length = 161 Score = 86.7 bits (213), Expect = 3e-17, Method: Composition-based stats. Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 15/94 (15%) Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKG 483 PD GVPSD L ++ + ++E +VHC GIGRTGT + +++ Sbjct: 68 PDGGVPSDSQ-FLTIMKWLLSEKEGN------LVHCVGGIGRTGTILASYLIL------- 113 Query: 484 VDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMA 517 ++V I VR R G VQT Q F+ Sbjct: 114 -TEGLEVESAIDEVRLVRPGAVQTYEQEMFLLRV 146 >4E93-A nrPDB Length = 377 Score = 86.7 bits (213), Expect = 3e-17, Method: Composition-based stats. Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 5/103 (4%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + + W+H I E LL+ G FL R S+ ++ LSV +G H IQ+ Sbjct: 10 LHEQLWYHGAIPRAEVAELLV---HSGDFLVRESQGKQ-EYVLSVLWDGLPRHFIIQSLD 65 Query: 61 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 + Y L GE F ++ L+ + + L +K+G V+ P + Sbjct: 66 NLYRL-EGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVPKD 107 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 35/121 (28%), Positives = 56/121 (46%), Gaps = 17/121 (14%) Query: 108 TSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKV 167 + W+HG + E +LL G FLVRESQ ++VLSV DG + Sbjct: 11 HEQLWYHGAIPRAEVAELLV---HSGDFLVRESQGK-QEYVLSV--------LWDGLPR- 57 Query: 168 THVMIRCQELKYDVGGGERFDSLTDLVEHY--KKNPMVETLGTVLQLKQPLNTTRINAAE 225 H +I+ + Y + GE F S+ L++H + P+ + G VL P + +N + Sbjct: 58 -HFIIQSLDNLYRL-EGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVPKDKWVLNHED 115 Query: 226 I 226 + Sbjct: 116 L 116 >2HDV-A nrPDB Length = 111 Score = 82.8 bits (203), Expect = 4e-16, Method: Composition-based stats. Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 12/99 (12%) Query: 111 RWFHGHLSGKEAEKLLTEKG--KHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVT 168 WFHG LS +A +L+ E G HG FLVR+S++ G+ VL+ + K Sbjct: 10 PWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRRGECVLTFNF----------QGKAK 59 Query: 169 HVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLG 207 H+ + F S+ D++EH++ +P+ G Sbjct: 60 HLRLSLNAAGQCRVQHLHFQSIFDMLEHFRVHPIPLESG 98 Score = 69.7 bits (169), Expect = 4e-12, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 41/90 (45%), Gaps = 2/90 (2%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGV--DGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQN 58 ++ WFH ++ ++A L+L G G FL R S++ G+ L+ G H+++ Sbjct: 6 LSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRRGECVLTFNFQGKAKHLRLSL 65 Query: 59 TGDYYDLYGGEKFATLAELVQYYMEHHGQL 88 F ++ ++++++ H L Sbjct: 66 NAAGQCRVQHLHFQSIFDMLEHFRVHPIPL 95 >2EYZ-A nrPDB Length = 304 Score = 81.6 bits (200), Expect = 9e-16, Method: Composition-based stats. Identities = 29/125 (23%), Positives = 47/125 (37%), Gaps = 18/125 (14%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDY--- 62 W+ ++ EA LL G FL R S ++PGD+ LSV N V+H I ++G Sbjct: 13 WYWGRLSRQEAVALL-QGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPV 71 Query: 63 --------------YDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPT 108 G ++F +L L+++Y H+ V + Sbjct: 72 PPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVILRQ 131 Query: 109 SERWF 113 E + Sbjct: 132 EEAEY 136 Score = 80.1 bits (196), Expect = 3e-15, Method: Composition-based stats. Identities = 37/117 (31%), Positives = 52/117 (44%), Gaps = 28/117 (23%) Query: 103 NCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESND 162 N W+ G LS +EA LL + +HG FLVR+S + PGD+VLSV Sbjct: 4 NFDSEERSSWYWGRLSRQEAVALL-QGQRHGVFLVRDSSTSPGDYVLSVSEN-------- 54 Query: 163 GKSKVTHVMIRCQELKYDVG-----------------GGERFDSLTDLVEHYKKNPM 202 S+V+H +I + V G + FDSL L+E YK + + Sbjct: 55 --SRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYL 109 >1RPY-A nrPDB Length = 114 Score = 80.9 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 14/106 (13%) Query: 105 ADPTSERWFHGHLSGKEAEKLLTEKG--KHGSFLVRESQSHPGDFVLSVRTGDDKGESND 162 + + WFHG LS +A +L+ G HG F++R+S++ PG+ VL T + +G++ Sbjct: 6 LELSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVL---TFNFQGKAKH 62 Query: 163 GKSKVT-HVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLG 207 + + H Q L F S+ D++ H+ +P+ G Sbjct: 63 LRLSLNGHGQCHVQHL--------WFQSVFDMLRHFHTHPIPLESG 100 Score = 69.7 bits (169), Expect = 3e-12, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 47/101 (46%), Gaps = 2/101 (1%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGV--DGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQN 58 ++ WFH ++ V+A L+L G G F+ R S++ PG+ L+ G H+++ Sbjct: 8 LSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSL 67 Query: 59 TGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELK 99 G F ++ ++++++ H L+ I L+ Sbjct: 68 NGHGQCHVQHLWFQSVFDMLRHFHTHPIPLESGGSADITLR 108 >5M6U-B nrPDB Length = 724 Score = 74.3 bits (181), Expect = 1e-13, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 65/156 (41%), Gaps = 13/156 (8%) Query: 103 NCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSH-PGDFVLSVRTGDDKGESN 161 N W+ G +S +E + L + G+FLVR++ + GD+ L++R G + Sbjct: 324 NNMSLQDAEWYWGDISREEVNEKLRDT-ADGTFLVRDASTKMHGDYTLTLRKGGNNKL-- 380 Query: 162 DGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE-TLGTVLQLKQPLNTTR 220 + I ++ KY F S+ +L+ HY+ + + ++L P++ + Sbjct: 381 --------IKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQ 432 Query: 221 INAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQ 256 + E + + K + Q E++ L + Sbjct: 433 QDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYE 468 Score = 71.2 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 4/102 (3%) Query: 2 TSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61 + W + +AENLL DG+FL R S S G + SV +G V H I T Sbjct: 620 DEKTWNVGSSNRNKAENLL-RGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTAT 677 Query: 62 YYDLYGG-EKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 102 Y +++L ELV +Y + + + L YP+ Sbjct: 678 GYGFAEPYNLYSSLKELVLHYQHTSLV-QHNDSLNVTLAYPV 718 Score = 68.6 bits (166), Expect = 8e-12, Method: Composition-based stats. Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 3/104 (2%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARP-SKSNPGDFTLSVRRNGAVTHIKIQNT 59 + W+ +I+ E L DG+FL R S GD+TL++R+ G IKI + Sbjct: 328 LQDAEWYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR 386 Query: 60 GDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 Y F+++ EL+ +Y + + ++L YP++ Sbjct: 387 DGKYGFSDPLTFSSVVELINHY-RNESLAQYNPKLDVKLLYPVS 429 Score = 59.3 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 30/116 (25%), Positives = 45/116 (38%), Gaps = 14/116 (12%) Query: 107 PTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSK 166 + W G + +AE LL K + G+FLVRES G + SV + Sbjct: 619 HDEKTWNVGSSNRNKAENLLRGK-RDGTFLVRESSKQ-GCYACSV----------VVDGE 666 Query: 167 VTHVMIRCQELKYDVGGGER-FDSLTDLVEHYKKNPMV-ETLGTVLQLKQPLNTTR 220 V H +I Y + SL +LV HY+ +V + L P+ + Sbjct: 667 VKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQ 722 >1XA6-A nrPDB Length = 466 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 29/84 (34%), Positives = 49/84 (58%), Gaps = 14/84 (16%) Query: 111 RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHV 170 R FHG +S ++A++LL G G++++RESQ PG + L++R G+ ++ H Sbjct: 56 REFHGIISREQADELL--GGVEGAYILRESQRQPGCYTLALRFGNQTLNY-----RLFH- 107 Query: 171 MIRCQELKYDVGGGERFDSLTDLV 194 + K+ V G +RF+S+ DLV Sbjct: 108 -----DGKHFV-GEKRFESIHDLV 125 Score = 66.6 bits (161), Expect = 3e-11, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 43/73 (58%), Gaps = 4/73 (5%) Query: 7 FHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLY 66 FH I+ +A+ LL GV+G+++ R S+ PG +TL++R + ++ + G ++ Sbjct: 58 FHGIISREQADELL--GGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHF--V 113 Query: 67 GGEKFATLAELVQ 79 G ++F ++ +LV Sbjct: 114 GEKRFESIHDLVT 126 >3CXL-A nrPDB Length = 463 Score = 73.2 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 31/128 (24%) Query: 111 RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHV 170 R FHG +S + A++LL GS+L+RESQ PG + L++R G Sbjct: 52 REFHGMISREAADQLLIVA--EGSYLIRESQRQPGTYTLALRFGSQTRNFR--------- 100 Query: 171 MIRCQELKYDVGGGERFDSLTDLV--------------EHYKK---NPMVETLGTVLQLK 213 + K+ V G +RF+S+ DLV E+ K NP+ E +G + Sbjct: 101 --LYYDGKHFV-GEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNR 157 Query: 214 QPLNTTRI 221 +P + Sbjct: 158 EPAYKKHM 165 Score = 69.3 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 50/117 (42%), Gaps = 9/117 (7%) Query: 7 FHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLY 66 FH I+ A+ LL+ +GS+L R S+ PG +TL++R + ++ G ++ Sbjct: 54 FHGMISREAADQLLIVA--EGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHF--V 109 Query: 67 GGEKFATLAELV-----QYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLS 118 G ++F ++ +LV Y+E + + + E + H+ Sbjct: 110 GEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMP 166 >2VIF-A nrPDB Length = 141 Score = 68.6 bits (166), Expect = 7e-12, Method: Composition-based stats. Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 7/115 (6%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + + W+ IT EAE L DGSFL R S + +LS R +G H +I+++ Sbjct: 21 LAKQGWYWGPITRWEAEGKLANVP-DGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSN 79 Query: 61 DYYDLYGG---EKFATLAELVQYY---MEHHGQLKEKNGDVIELKYPLNCADPTS 109 + Y E ++ +L+++ E+ ++ YP+ +P S Sbjct: 80 GRFSFYEQPDVEGHTSIVDLIEHSIGDSENGAFCYSRSRLPGSATYPVRLTNPVS 134 Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 28/122 (22%), Positives = 48/122 (39%), Gaps = 25/122 (20%) Query: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTH 169 + W+ G ++ EAE L GSFLVR+S ++LS+ K H Sbjct: 24 QGWYWGPITRWEAEGKLANVP-DGSFLVRDSSDDR--YLLSLSFRSH--------GKTLH 72 Query: 170 VMIRCQELK---YDVGGGERFDSLTDLVEH-----------YKKNPMVETLGTVLQLKQP 215 I + Y+ E S+ DL+EH Y ++ + + ++L P Sbjct: 73 TRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIGDSENGAFCYSRSRLPGSATYPVRLTNP 132 Query: 216 LN 217 ++ Sbjct: 133 VS 134 >3QWY-A nrPDB Length = 308 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 41/160 (25%), Positives = 63/160 (39%), Gaps = 25/160 (15%) Query: 111 RW---FHGHLSGKEAEKLLTEKGKH-GSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSK 166 W + +S +EA KLL E G+FL+R+S S PG++ L+VR D+ Sbjct: 39 EWRSFYFPGMSREEAHKLLGEPQVSIGTFLMRDS-SRPGEYSLTVREADEGNA------- 90 Query: 167 VTHVMIRCQELKYD-------VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPL--- 216 V H +I E K D + F + L+ H+K + E + K+P+ Sbjct: 91 VCHYLIERGEPKEDGTAAAGVKIANQSFPDIPALLNHFKMRVLTE-ASLLAAYKKPIIEV 149 Query: 217 --NTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETL 254 T + E + E K Q +WE L Sbjct: 150 VVGTFKFTGERETDLPFEQGERLEILSKTNQDWWEARNAL 189 Score = 62.4 bits (150), Expect = 6e-10, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 12/90 (13%) Query: 4 RRWFHPNITGVEAENLLLTRGVD-GSFLARPSKSNPGDFTLSVR---RNGAVTHIKI--- 56 R ++ P ++ EA LL V G+FL R S S PG+++L+VR AV H I Sbjct: 41 RSFYFPGMSREEAHKLLGEPQVSIGTFLMRDS-SRPGEYSLTVREADEGNAVCHYLIERG 99 Query: 57 QNTGDYYDLYG----GEKFATLAELVQYYM 82 + D G + F + L+ ++ Sbjct: 100 EPKEDGTAAAGVKIANQSFPDIPALLNHFK 129 >4JGH-A nrPDB Length = 173 Score = 59.7 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 28/119 (23%), Positives = 54/119 (45%), Gaps = 14/119 (11%) Query: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65 W+ ++T EA+ L +G+FL R S + T+SV+ + T+++I+ + L Sbjct: 23 WYWGSMTVNEAKEKLKEAP-EGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRL 81 Query: 66 YGG-------EKFATLAELVQYY-----MEHHGQLKEKNGDV-IELKYPLNCADPTSER 111 ++F ++ L+ YY + G +NG V + L PL + P+ + Sbjct: 82 DSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPSLQH 140 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 26/123 (21%) Query: 112 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 171 W+ G ++ EA++ L E G+FL+R+S D++L++ G +N + Sbjct: 23 WYWGSMTVNEAKEKLKEAP-EGTFLIRDSSHS--DYLLTISVKTSAGPTN--------LR 71 Query: 172 IRCQELKYDVGG-------GERFDSLTDLVEHY-------KKNPMVETLGTV-LQLKQPL 216 I Q+ K+ + ++FDS+ L+++Y + P GTV L L +PL Sbjct: 72 IEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPL 131 Query: 217 NTT 219 T+ Sbjct: 132 YTS 134 >4ERC-A nrPDB Length = 150 Score = 58.5 bits (140), Expect = 7e-09, Method: Composition-based stats. Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 12/93 (12%) Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKG 483 PD P P + F++ V E+ V VHC+ G GRTGT + +++E+G Sbjct: 64 PDF-CPPAPDQIDRFVQIVD---EANARGEAVGVHCALGFGRTGTMLA----CYLVKERG 115 Query: 484 VDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYM 516 + I +R R G ++T Q + ++ Sbjct: 116 LAAG----DAIAEIRRLRPGSIETYEQEKAVFQ 144 >6C5X-D nrPDB Length = 164 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 42/89 (47%), Gaps = 2/89 (2%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + + ++ + A + L + + G+FL R SK F +SV+ I+I+ Sbjct: 27 LDTCGFYWGPMDVNVAHDKLKSEPI-GTFLIRDSKQKNCFFAISVKTARETVSIRIKFHA 85 Query: 61 DYYDLYG-GEKFATLAELVQYYMEHHGQL 88 + L G E F+ L +LV++YM ++ Sbjct: 86 GKFSLDGSKELFSCLFQLVEHYMTSPKKM 114 Score = 52.0 bits (123), Expect = 8e-07, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 15/104 (14%) Query: 113 FHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI 172 + G + A L + G+FL+R+S+ F +SV+T + + I Sbjct: 33 YWGPMDVNVAHDKLKSEPI-GTFLIRDSKQKNCFFAISVKTARETVS----------IRI 81 Query: 173 RCQELKYDVGGGER-FDSLTDLVEHYKKNPMVETLGTVLQLKQP 215 + K+ + G + F L LVEHY +P V L++ Sbjct: 82 KFHAGKFSLDGSKELFSCLFQLVEHYMTSP---KKMLVSPLRKV 122 >2HMH-A nrPDB Length = 152 Score = 56.2 bits (134), Expect = 4e-08, Method: Composition-based stats. Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 8/89 (8%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + ++ +TG EA NLLL+ G+FL R S FTLSV+ +++IQ G Sbjct: 31 LQESGFYWSAVTGGEA-NLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEG 89 Query: 61 DYYDLYGG-------EKFATLAELVQYYM 82 + L +F + +LV +YM Sbjct: 90 GSFSLQSDPRSTQPVPRFDCVLKLVHHYM 118 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 18/93 (19%) Query: 113 FHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI 172 + ++G EA LL+ + G+FL+R+S F LSV+T + I Sbjct: 37 YWSAVTGGEANLLLSAEPA-GTFLIRDSSDQRHFFTLSVKTQSGTKN----------LRI 85 Query: 173 RCQELKYDVGGG-------ERFDSLTDLVEHYK 198 +C+ + + RFD + LV HY Sbjct: 86 QCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYM 118 >4GL9-E nrPDB Length = 143 Score = 55.8 bits (133), Expect = 5e-08, Method: Composition-based stats. Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 8/89 (8%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + ++ +TG EA NLLL+ G+FL R S FTLSV+ +++IQ G Sbjct: 25 LQESGFYWSAVTGGEA-NLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEG 83 Query: 61 DYYDLYGG-------EKFATLAELVQYYM 82 + L +F + +LV +YM Sbjct: 84 GSFSLQSDPRSTQPVPRFDCVLKLVHHYM 112 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 18/93 (19%) Query: 113 FHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI 172 + ++G EA LL+ + G+FL+R+S F LSV+T + I Sbjct: 31 YWSAVTGGEANLLLSAEPA-GTFLIRDSSDQRHFFTLSVKTQSGTKN----------LRI 79 Query: 173 RCQELKYDVGGG-------ERFDSLTDLVEHYK 198 +C+ + + RFD + LV HY Sbjct: 80 QCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYM 112 >2BBU-A nrPDB Length = 164 Score = 55.8 bits (133), Expect = 5e-08, Method: Composition-based stats. Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 8/94 (8%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + ++ +TG EA NLLL+ G+FL R S FTLSV+ +++IQ G Sbjct: 20 LQESGFYWSAVTGGEA-NLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEG 78 Query: 61 DYYDLYGG-------EKFATLAELVQYYMEHHGQ 87 + L +F + +LV +YM G Sbjct: 79 GSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGT 112 Score = 48.5 bits (114), Expect = 9e-06, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 41/104 (39%), Gaps = 18/104 (17%) Query: 113 FHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI 172 + ++G EA LL+ + G+FL+R+S F LSV+T + I Sbjct: 26 YWSAVTGGEANLLLSAEPA-GTFLIRDSSDQRHFFTLSVKTQSGTKN----------LRI 74 Query: 173 RCQELKYDVGGG-------ERFDSLTDLVEHYKKNPMVETLGTV 209 +C+ + + RFD + LV HY P + Sbjct: 75 QCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGTPSFSLP 118 >6C7Y-B nrPDB Length = 117 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + + ++ +T A L + +G+FL R S F +SV+ T I+I Sbjct: 23 LDACGFYWGPLTVSAAHEKLKSEP-EGTFLIRDSTQKNCFFAISVKTATGPTSIRINFQT 81 Query: 61 DYYDLYG-GEKFATLAELVQYY 81 + L G E F L +L+++Y Sbjct: 82 GRFSLDGSKETFDCLFKLLEHY 103 Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 15/103 (14%) Query: 113 FHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI 172 + G L+ A + L + G+FL+R+S F +SV+T + I Sbjct: 29 YWGPLTVSAAHEKLKSEP-EGTFLIRDSTQKNCFFAISVKTATGPTS----------IRI 77 Query: 173 RCQELKYDVGG-GERFDSLTDLVEHYKKNPMVETLGTVLQLKQ 214 Q ++ + G E FD L L+EHY +P V L++ Sbjct: 78 NFQTGRFSLDGSKETFDCLFKLLEHYLSSP---RKVLVTPLRK 117 >5Z59-A nrPDB Length = 147 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 12/91 (13%) Query: 424 PDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKG 483 PD P +L+ L + + V++HC G+GR+GT + + L+ Sbjct: 62 PDFTAP-SVEQLLEILRWIEERVREGKK---VLIHCMGGLGRSGT-VGVAWLMY------ 110 Query: 484 VDCDIDVPKTIQMVRSQRSGMVQTEAQYRFI 514 + + + + VR +R G V+T+ Q + Sbjct: 111 -SRGLSLREALMEVRRKRPGAVETQEQMEVL 140 >1G4W-R nrPDB Length = 383 Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 31/178 (17%), Positives = 69/178 (38%), Gaps = 19/178 (10%) Query: 343 RMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELK 402 +M+ ++ +V+ T E + + Y+ +G + + K S+A + Sbjct: 202 KMLLEKECSCLVVLTSEDQMQAKQLPPYF---RGSYTFGEVHTNSQKVSSASQGEAIDQY 258 Query: 403 LSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHK-------QESIMDAGPV 455 ++ G T+ H + WPDH + + V + + S P+ Sbjct: 259 NMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPM 318 Query: 456 VVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSG-MVQTEAQYR 512 + HC G+GRTGT + +++ + ++ + R R+ M++ +Q+ Sbjct: 319 I-HCLGGVGRTGT-MAAALVL------KDNPHSNLEQVRADFRDSRNNRMLEDASQFV 368 >5LXQ-B nrPDB Length = 196 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 35/88 (39%), Gaps = 11/88 (12%) Query: 418 YHFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 H WP D G P V D+L V K + VHC AG+GR + + ++ Sbjct: 86 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCC-IAVHCVAGLGRAPVLVALALIE 144 Query: 477 DIIREKGVDCDIDVPKTIQMVRSQRSGM 504 ++ + +Q +R +R G Sbjct: 145 GGMKYE---------DAVQFIRQKRRGA 163 >3RZ2-A nrPDB Length = 189 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 35/88 (39%), Gaps = 11/88 (12%) Query: 418 YHFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 H WP D G P V D+L V K + VHC AG+GR + + ++ Sbjct: 83 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCC-IAVHCVAGLGRAPVLVALALIE 141 Query: 477 DIIREKGVDCDIDVPKTIQMVRSQRSGM 504 ++ + +Q +R +R G Sbjct: 142 GGMKYE---------DAVQFIRQKRRGA 160 >1ZCK-A nrPDB Length = 154 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 35/88 (39%), Gaps = 11/88 (12%) Query: 418 YHFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 H WP D G P V D+L V K + VHC AG+GR + + ++ Sbjct: 57 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCC-IAVHCVAGLGRAPVLVALALIE 115 Query: 477 DIIREKGVDCDIDVPKTIQMVRSQRSGM 504 ++ + +Q +R +R G Sbjct: 116 GGMKYE---------DAVQFIRQKRRGA 134 >5K23-A nrPDB Length = 189 Score = 48.9 bits (115), Expect = 7e-06, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 41/120 (34%), Gaps = 12/120 (10%) Query: 387 NVKESAAHDYTLREL-KLSKVGQGNTERTVWQYHFRTWP-DHGVPSDPGGVLDFLEEVHH 444 N Y + L ++ H WP D G P V D+L + Sbjct: 50 NKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKT 109 Query: 445 KQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGM 504 K V VHC AG+GR + + ++ ++ + +Q +R +R G Sbjct: 110 KFREEPGCC-VAVHCVAGLGRAPVLVALALIECGMKYE---------DAVQFIRQKRRGA 159 >5XW4-A nrPDB Length = 415 Score = 48.5 bits (114), Expect = 9e-06, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 9/65 (13%) Query: 453 GPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ-Y 511 G + VHC AG+GRTG I ++ + I +R R GMV Q + Sbjct: 318 GKIAVHCKAGLGRTGCLIGAHLI--------YTYGFTANECIGFLRFIRPGMVVGPQQHW 369 Query: 512 RFIYM 516 +++ Sbjct: 370 LYLHQ 374 >1V3A-A nrPDB Length = 173 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 11/86 (12%) Query: 421 RTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII 479 WP D G P V D+L V K + V VHC AG+GR + + ++ + Sbjct: 66 VDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESGM 124 Query: 480 REKGVDCDIDVPKTIQMVRSQRSGMV 505 + + IQ +R +R G + Sbjct: 125 KYE---------DAIQFIRQKRRGAI 141 >1OHC-A nrPDB Length = 348 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 15/86 (17%) Query: 425 DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGV 484 D P+D ++E E+ G + VHC AG+GRTGT I I+ Sbjct: 249 DGSTPTDA-----IVKEFLDICENA--EGAIAVHCKAGLGRTGTLIACYIMKH------- 294 Query: 485 DCDIDVPKTIQMVRSQRSGMVQTEAQ 510 + +TI VR R G V Q Sbjct: 295 -YRMTAAETIAWVRICRPGSVIGPQQ 319 >2EL8-A nrPDB Length = 118 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 6/81 (7%) Query: 10 NITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVR--RNGA--VTHIKIQNTGDYYDL 65 ++ +EA+ LL G+ L RPS +++ R NG V H K++ G Y + Sbjct: 27 KVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVI 86 Query: 66 YGGEKFA--TLAELVQYYMEH 84 + F+ +L +V Y++ H Sbjct: 87 DVEQPFSCTSLDAVVNYFVSH 107 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 8/88 (9%) Query: 116 HLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQ 175 +S EA+ LL + G+ L+R S G +SV T + ++G V H ++ + Sbjct: 27 KVSRLEAQLLLERYPECGNLLLRPSGD--GADGVSVTT----RQMHNGTHVVRHYKVKRE 80 Query: 176 ELKYDVGGGERFD--SLTDLVEHYKKNP 201 KY + + F SL +V ++ + Sbjct: 81 GPKYVIDVEQPFSCTSLDAVVNYFVSHT 108 >1XM2-A nrPDB Length = 173 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 34/88 (38%), Gaps = 11/88 (12%) Query: 418 YHFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 H WP D G P V D+L V K + VH AG+GR + + ++ Sbjct: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCC-IAVHSVAGLGRAPVLVALALIE 121 Query: 477 DIIREKGVDCDIDVPKTIQMVRSQRSGM 504 ++ + +Q +R +R G Sbjct: 122 GGMKYE---------DAVQFIRQKRRGA 140 >5K22-A nrPDB Length = 183 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 42/120 (35%), Gaps = 12/120 (10%) Query: 387 NVKESAAHDYTLREL-KLSKVGQGNTERTVWQYHFRTWP-DHGVPSDPGGVLDFLEEVHH 444 N Y + L ++ H WP D G P V D+L + Sbjct: 48 NKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKT 107 Query: 445 KQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGM 504 K A V VHC AG+GR + + ++ ++ + +Q +R +R G Sbjct: 108 KFREEPGAA-VAVHCVAGLGRAPVLVALALIEAGMKYE---------DAVQFIRQKRRGA 157 >3S4O-A nrPDB Length = 167 Score = 45.1 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 31/165 (18%), Positives = 59/165 (35%), Gaps = 26/165 (15%) Query: 367 CVKYWPDEYALKEYGVMRVRNVKESAAHDYT-------LREL-KLSKVGQGNTERTVWQY 418 C P + + + + + S Y +R L ++ T Sbjct: 13 CD---PQKPSRVLFHFLILDAPSPSNLPTYIKELQHRGVRHLVRVCGPTYDATLVKSRGI 69 Query: 419 HFRTWP-DHGVPSDPGGVLDFLE----EVHHKQESIMDAGPVV-VHCSAGIGRTGTFIVI 472 +WP D G P + +L+ E+ +QE P + VHC AG+GR + + Sbjct: 70 DVHSWPFDDGAPPTRAVLDSWLKLLDTELARQQEDPSVPPPTIGVHCVAGLGRAPILVAL 129 Query: 473 DILIDIIREKGVDCDIDVPKTIQMVRSQRSGMV-QTEAQYRFIYM 516 ++ ++ I ++R +R G + QT+ + Y Sbjct: 130 ALV--------EYGNVSALDAIALIREKRKGAINQTQMHWITKYK 166 >1FPZ-A nrPDB Length = 212 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 24/127 (18%), Positives = 48/127 (37%), Gaps = 18/127 (14%) Query: 415 VWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDI 474 + +H D G P D + +EE+ ++ ++H G+GR+ + + Sbjct: 102 ITHHHPIA--DGGTP-DIASCCEIMEELTTCLKNYRKT---LIHSYGGLGRS-CLVAACL 154 Query: 475 LIDIIREKGVDCDIDVPKTIQMVRSQR-SGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQ 533 L+ + + ID +R R SG +QT QY +++ + + L + Sbjct: 155 LLYLSDTISPEQAID------SLRDLRGSGAIQTIKQYNYLH----EFRDKLAAHLSSRD 204 Query: 534 KSKRKGH 540 R Sbjct: 205 SQSRSVS 211 >2CR4-A nrPDB Length = 126 Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 43/104 (41%), Gaps = 14/104 (13%) Query: 121 EAEKLLTE-----KGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQ 175 E E+L + + G + +R S + G VL V ++ +KV + I + Sbjct: 28 EVERLFKATSPRGEPQDGLYCIRNSSTKSGK-VLVV--------WDETSNKVRNYRIFEK 78 Query: 176 ELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTT 219 + K+ + G F S+ +VEHY + + +L+ + Sbjct: 79 DSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTSG 122 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 35/97 (36%), Gaps = 12/97 (12%) Query: 15 EAENLLLT-----RGVDGSFLARPSKSNPGDFTLSV--RRNGAVTHIKIQNTGDYYDLYG 67 E E L DG + R S + G L V + V + +I + L G Sbjct: 28 EVERLFKATSPRGEPQDGLYCIRNSSTKSGK-VLVVWDETSNKVRNYRIFEKDSKFYLEG 86 Query: 68 GEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNC 104 F ++ +V++Y H + + L++P Sbjct: 87 EVLFVSVGSMVEHYHTHVLPSHQS----LLLRHPYGY 119 >5BZX-A nrPDB Length = 314 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 28/135 (20%), Positives = 48/135 (35%), Gaps = 8/135 (5%) Query: 382 VMRVRNVKESAAHDYTLRELKLSKVGQGNTER-TVWQYHFRTWPDHGVPSDPGGVLDFLE 440 VR + + Y + L + V QY F DH P ++ Sbjct: 38 DDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFE---DHNPPQ--LELIKPFC 92 Query: 441 EVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQ 500 E + S D +HC AG GRTG I L+ + +D ++ R + Sbjct: 93 EDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAY-LLHRGKFLKAQEALDFYGEVRT-RDK 150 Query: 501 RSGMVQTEAQYRFIY 515 + + ++ +Y + Y Sbjct: 151 KGVTIPSQRRYVYYY 165 >3V0J-A nrPDB Length = 334 Score = 43.1 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 38/90 (42%), Gaps = 6/90 (6%) Query: 425 DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGV 484 DH VP +L F+++ S D + +H G GRTGT + ++ + Sbjct: 94 DHNVP-TLVDLLKFIDDAKVWMTSDPDHV-IAIHSKGGKGRTGTLVSS----WLLEDGKF 147 Query: 485 DCDIDVPKTIQMVRSQRSGMVQTEAQYRFI 514 D + + R+ V+T +Q R++ Sbjct: 148 DTAKEALEYFGSRRTDVFQGVETASQIRYV 177 >1UUS-A nrPDB Length = 473 Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 42/103 (40%), Gaps = 15/103 (14%) Query: 97 ELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDD 156 L+Y + + E +G++ +E L + G+F++R S+ +PG F ++ Sbjct: 338 TLRYQRHISTLWQEGIIYGYMGRQEVNDALQNQ-DPGTFIIRFSERNPGQFGIAYI---- 392 Query: 157 KGESNDGKSKVTHVMIRCQELKY-------DVGGGERFDSLTD 192 + +++ H +++ + + +F +L Sbjct: 393 ---GVEMPARIKHYLVQPNDTAAAKKTFPDFLSEHSQFVNLLQ 432 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 29/79 (36%), Gaps = 11/79 (13%) Query: 8 HPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLS---VRRNGAVTHIKIQNTGDYY- 63 + + E + L + G+F+ R S+ NPG F ++ V + H +Q Sbjct: 355 YGYMGRQEVNDALQNQDP-GTFIIRFSERNPGQFGIAYIGVEMPARIKHYLVQPNDTAAA 413 Query: 64 ------DLYGGEKFATLAE 76 L +F L + Sbjct: 414 KKTFPDFLSEHSQFVNLLQ 432 >2WGP-A nrPDB Length = 190 Score = 41.6 bits (96), Expect = 9e-04, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 1/59 (1%) Query: 417 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDIL 475 Q+ + P +P P G L F G +VHC+AG+ R+ T + ++ Sbjct: 69 QFEYVKVPLADMPHAPIG-LYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLM 126 >5T2H-A nrPDB Length = 299 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 25/154 (16%), Positives = 55/154 (35%), Gaps = 24/154 (15%) Query: 132 HGSFL--VRESQSHPGDFVLSVR-----TGDDKGESNDGKSKVTHVMIRCQELKYDVGGG 184 GSF+ +R + + S+R DK + +S I + + Sbjct: 17 EGSFILDIRNRNNESNRYRTSLRFQITLHNKDKSILENIQSTWKVGKITNSSDRAVMLRV 76 Query: 185 ERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVK 244 RF+ L +++H++K P++ T+ ++ + E + +K Sbjct: 77 TRFEDLKVIIDHFEKYPLI---------------TQKLGDY--KLFKQAFSVMENKEHLK 119 Query: 245 QGFWEEFETLQQQECKLLYSRKEGQRQENKNKNR 278 + +E ++ + L + EN +K R Sbjct: 120 ENGIKELVRIKAKMNWGLNDELKKAFPENISKER 153 Score = 32.3 bits (72), Expect = 0.62, Method: Composition-based stats. Identities = 16/102 (15%), Positives = 36/102 (35%), Gaps = 18/102 (17%) Query: 26 DGSFL--ARPSKSNPGDFTLSVRRNGAVTHI---------------KIQNTGDYYDLYGG 68 +GSF+ R + + S+R + + KI N+ D + Sbjct: 17 EGSFILDIRNRNNESNRYRTSLRFQITLHNKDKSILENIQSTWKVGKITNSSDRAVMLRV 76 Query: 69 EKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSE 110 +F L ++ ++ ++ + +K GD K + + Sbjct: 77 TRFEDLKVIIDHFEKYPL-ITQKLGDYKLFKQAFSVMENKEH 117 >2IZV-A nrPDB Length = 187 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 38/92 (41%), Gaps = 5/92 (5%) Query: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60 + + + + AE LL + +G+FL R S F++S RR H +I+ Sbjct: 31 INNNPCYWGVMDKYAAEALLEGKP-EGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWN 89 Query: 61 DYYDLYGGE--KFAT--LAELVQYYMEHHGQL 88 + + F + + L+++Y + + Sbjct: 90 HNFSFDAHDPCVFHSPDITGLLEHYKDPSACM 121 Score = 38.5 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 39/110 (35%), Gaps = 14/110 (12%) Query: 113 FHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMI 172 + G + AE LL K G+FL+R+S D++ SV + + H Sbjct: 37 YWGVMDKYAAEALLEGKP-EGTFLLRDSAQE--DYLFSVSFRRYSRSLHARIEQWNHNFS 93 Query: 173 RCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRIN 222 +T L+EHYK + +PL +T + Sbjct: 94 FDAHDPCVFHS----PDITGLLEHYK-------DPSACMFFEPLLSTPLI 132 >3MAZ-A nrPDB Length = 125 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 39/79 (49%), Gaps = 8/79 (10%) Query: 11 ITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRN---GAVTHIKIQNTGDYYDLYG 67 ++ EA +L G+ + RP S+ ++++++R+ + H K+ + G Y + Sbjct: 22 VSRKEATEMLQKNPSLGNMILRPG-SDSRNYSITIRQEIDIPRIKHYKVMSVGQNYTI-E 79 Query: 68 GEKFATLAEL---VQYYME 83 EK TL L + Y+++ Sbjct: 80 LEKPVTLPNLFSVIDYFVK 98 >4Z32-A nrPDB Length = 497 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 29/82 (35%), Gaps = 7/82 (8%) Query: 8 HPNITGVEAENLLLTRGVD-GSFLARPSKSNPGDFTLSVRRNG----AVTHIKIQNTGDY 62 H I+ A + L G G ++ R S + + L+ H I + Sbjct: 372 HGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENE 431 Query: 63 YDLYGGEK--FATLAELVQYYM 82 G K F++L +L+ Y Sbjct: 432 EYNLSGTKKNFSSLKDLLNCYQ 453 >2G6Z-A nrPDB Length = 211 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 26/108 (24%), Positives = 43/108 (39%), Gaps = 20/108 (18%) Query: 403 LSKVGQGNTERTVWQYHFRTWP---DH--GVPSDPGGVLDFLEEVHHKQESIMDAGPVVV 457 L V + +E + H++ P H + S +DF++ V K G V+V Sbjct: 35 LLNVSRRTSEACMTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKG------GKVLV 88 Query: 458 HCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMV 505 H AGI R+ T + +++ K + I+ QR MV Sbjct: 89 HSEAGISRSPTIC----MAYLMKTKQFRLK-EAFDYIK----QRRSMV 127 >2RF6-A nrPDB Length = 176 Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 30/73 (41%), Gaps = 6/73 (8%) Query: 450 MDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEA 509 PV+VH +AG+ R+G I+ ++ + + V +R R V+ + Sbjct: 106 QRNEPVLVHSAAGVNRSGAMILAYLMSKNKESLPMLYFLYVY---HSMRDLRGAFVENPS 162 Query: 510 QYRFIYMAVQHYI 522 F ++ Y+ Sbjct: 163 ---FKRQIIEKYV 172 >4NX8-A nrPDB Length = 293 Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 5/64 (7%) Query: 425 DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGV 484 DH P D V F+E V E+ HC AG GRT TF+V+ ++ + Sbjct: 177 DHVRPVDSE-VDRFIESVRALPENAWVH----FHCRAGKGRTTTFMVLYDMLKNAKTDSF 231 Query: 485 DCDI 488 + I Sbjct: 232 EEII 235 >5THG-A nrPDB Length = 304 Score = 37.7 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 61/175 (34%), Gaps = 28/175 (16%) Query: 115 GHL-SGKEAEK---LLTEKGKHGSFLVRESQSHP---GDFVLSVR----TGDDKGESNDG 163 G + S +E+ L GSF++R ++ G + V DK + Sbjct: 2 GPMESRRESINPWILTGFTDAEGSFMLRIRNTNNRSVGYYTSLVFEITLHNKDKSILENI 61 Query: 164 KSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINA 223 +S I + RF+ L +++H++K P++ T+ Sbjct: 62 QSTWKVGTINNRGDGTARLSVTRFEDLKVIIDHFEKYPLI---------------TQKLG 106 Query: 224 AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNR 278 ++ + E + +K+ +E ++ + L + EN +K R Sbjct: 107 DY--KLFKQAFSVMENKEHLKENGIKELVRIKAKMNWGLNDELKKAFPENISKER 159 Score = 30.4 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 36/103 (34%), Gaps = 20/103 (19%) Query: 26 DGSFLARPSKSN---PGDFTLSVRRNGAVTHI---------------KIQNTGDYYDLYG 67 +GSF+ R +N G +T S+ + + I N GD Sbjct: 23 EGSFMLRIRNTNNRSVGYYT-SLVFEITLHNKDKSILENIQSTWKVGTINNRGDGTARLS 81 Query: 68 GEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSE 110 +F L ++ ++ ++ + +K GD K + + Sbjct: 82 VTRFEDLKVIIDHFEKYPL-ITQKLGDYKLFKQAFSVMENKEH 123 >4R0S-A nrPDB Length = 218 Score = 36.6 bits (83), Expect = 0.033, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 33/81 (40%), Gaps = 11/81 (13%) Query: 429 PSDPGGVLDF-LEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDIL----------ID 477 P+ V D + V + ++ GPV++HC G RTG F + + ++ Sbjct: 101 PTHADRVDDAEVLSVLRQLQAAEREGPVLMHCKHGNNRTGLFAAMYRIVVQGWDKQAALE 160 Query: 478 IIREKGVDCDIDVPKTIQMVR 498 ++ G + D+ VR Sbjct: 161 EMQHGGFGDEDDMRDASAYVR 181 >3D1Q-A nrPDB Length = 340 Score = 36.6 bits (83), Expect = 0.034, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 10/54 (18%) Query: 423 WPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 WP P + L F ++ + HC AG+GRT F+V+ ++ Sbjct: 220 WP---TPENIDRFLAF-------YRTLPQDAWLHFHCEAGVGRTTAFMVMTDML 263 >2M3V-A nrPDB Length = 193 Score = 36.2 bits (82), Expect = 0.042, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 33/81 (40%), Gaps = 11/81 (13%) Query: 429 PSDPGGVLDF-LEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDIL----------ID 477 P+ V D + V + ++ GPV++HC G RTG F + + ++ Sbjct: 76 PTHADRVDDAEVLSVLRQLQAAEREGPVLMHCKHGNNRTGLFAAMYRIVVQGWDKQAALE 135 Query: 478 IIREKGVDCDIDVPKTIQMVR 498 ++ G + D+ VR Sbjct: 136 EMQRGGFGDEDDMRDASAYVR 156 >4YR8-G nrPDB Length = 167 Score = 35.4 bits (80), Expect = 0.075, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 27/59 (45%), Gaps = 5/59 (8%) Query: 440 EEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR 498 + V +++ G V+VHC AGI R+ T I I ++ + + + ++ R Sbjct: 91 KSVDFIEKAKASNGCVLVHCLAGISRSAT-IAIAYIMKRMDMSLDEA----YRFVKEKR 144 >2OZ5-A nrPDB Length = 296 Score = 35.0 bits (79), Expect = 0.087, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 11/59 (18%) Query: 454 PVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQ------MVRSQRSGMVQ 506 PV+ HC AG RTG + + ++ G+D D+ V ++ +R++ S M+Q Sbjct: 175 PVLTHCFAGKDRTGFVVAL-----VLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQ 228 >5T2O-A nrPDB Length = 302 Score = 35.0 bits (79), Expect = 0.093, Method: Composition-based stats. Identities = 24/154 (15%), Positives = 52/154 (33%), Gaps = 24/154 (15%) Query: 132 HGSF--LVRESQSHPGDFVLSV-----RTGDDKGESNDGKSKVTHVMIRCQELKYDVGGG 184 GSF +R + P + + DK + +S +I Sbjct: 21 EGSFSLYIRNTNDRPSRYETRLTFAIGLHYKDKSILENIQSTWKVGIITNAGNNVVQLRV 80 Query: 185 ERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVK 244 RF+ L +++H++K P++ T+ ++ + E + +K Sbjct: 81 SRFEDLKVIIDHFEKYPLI---------------TQKLGDY--KLFKQAFSVMENKEHLK 123 Query: 245 QGFWEEFETLQQQECKLLYSRKEGQRQENKNKNR 278 + +E ++ + L + EN +K R Sbjct: 124 ENGIKELVRIKAKMNWGLNDELKKAFPENISKER 157 >6N8N-Y nrPDB Length = 364 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 37/101 (36%), Gaps = 20/101 (19%) Query: 385 VRNVKESAAHDYTLRE-LKLSKVG-QGNTERTVWQYHFRTWPDHGVPSDPGGVLD---FL 439 + +K +Y +R+ L + + V QY + +D F Sbjct: 43 LSVIKFQVIPEYLIRKGYTLKNIPIDDDDVTDVLQYF----------DETNRFIDQCLFP 92 Query: 440 EEVHHKQESI-----MDAGPVVVHCSAGIGRTGTFIVIDIL 475 EV + + G V HC AG+ R+ TFIV ++ Sbjct: 93 NEVEYSPRLVDFKKKPQRGAVFAHCQAGLSRSVTFIVAYLM 133 >6BDA-A nrPDB Length = 307 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 18/150 (12%) Query: 117 LSGKEAEK---LLTEKGKHGSFLVRESQSHPGD--------FVLSVRTGDDKGESNDGKS 165 +S +E+ L GSFL+R ++ F +++ DK + +S Sbjct: 8 MSRRESINPWILTGFADAEGSFLLRIRNNNKSSVGYSTELGFQITL-HNKDKSILENIQS 66 Query: 166 KVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMV-ETLGTVLQLKQ----PLNTTR 220 +I RF+ L +++H++K P++ + LG + KQ N Sbjct: 67 TWKVGVIANSGDNAVSLKVTRFEDLKVIIDHFEKYPLITQKLGDYMLFKQAFCVMENKEH 126 Query: 221 INAAEIESRVRELSKLAET-TDKVKQGFWE 249 + I+ VR +KL TD++K F E Sbjct: 127 LKINGIKELVRIKAKLNWGLTDELKFAFPE 156 >1Y1U-A nrPDB Length = 585 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 27/66 (40%), Gaps = 2/66 (3%) Query: 115 GHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTH-VMIR 173 G ++ ++A LL K G+FL+R S S G ++ + + K T IR Sbjct: 469 GFVNKQQAHDLLINKP-DGTFLLRFSDSEIGGITIAWKFDSPDRNLWNLKPFTTRDFSIR 527 Query: 174 CQELKY 179 + Sbjct: 528 SLADRL 533 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 22/41 (53%), Gaps = 1/41 (2%) Query: 9 PNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNG 49 + +A +LL+ + DG+FL R S S G T++ + + Sbjct: 469 GFVNKQQAHDLLINKP-DGTFLLRFSDSEIGGITIAWKFDS 508 >1M3G-A nrPDB Length = 145 Score = 34.3 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 28/63 (44%), Gaps = 11/63 (17%) Query: 436 LDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQ 495 + F++ V + G V+VH AGI R+ T + +++ + V D + ++ Sbjct: 71 IGFIDWVKNSG------GRVLVHSQAGISRSATICLAY----LMQSRRVRLD-EAFDFVK 119 Query: 496 MVR 498 R Sbjct: 120 QRR 122 >6D67-A nrPDB Length = 520 Score = 34.3 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 38/88 (43%), Gaps = 16/88 (18%) Query: 417 QYHFRTWP---DH--GVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIV 471 Y +++ P +H + S +DF++ + + G V VH AGI R+ T + Sbjct: 417 HYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAG------GRVFVHSQAGISRSATICL 470 Query: 472 IDILIDIIREKGVDCDIDVPKTIQMVRS 499 ++R V D + + ++ RS Sbjct: 471 AY----LMRTNRVKLD-EAFEFVKQRRS 493 >3EZZ-A nrPDB Length = 144 Score = 34.3 bits (77), Expect = 0.16, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 20/39 (51%) Query: 438 FLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 F+E + + G V+VH AGI R+ T + +++ Sbjct: 67 FMEAIEYIDAVKDCRGRVLVHSQAGISRSATICLAYLMM 105 >1WRM-A nrPDB Length = 165 Score = 33.9 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 39/108 (36%), Gaps = 20/108 (18%) Query: 436 LDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQ 495 + F+ E + ES +VHC AG+ R+ T ++ I+ D + Sbjct: 73 IKFIHECRLRGESC------LVHCLAGVSRSVTLVIAYIM--------TVTDFGWEDALH 118 Query: 496 MVRSQRSGM-----VQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRK 538 VR+ RS Q + Q F V Y + L+ E + Sbjct: 119 TVRAGRSCANPNVGFQRQLQ-EFEKHEVHQYRQWLKEEYGESPLQDAE 165 >3F41-A nrPDB Length = 629 Score = 33.9 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 5/57 (8%) Query: 425 DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIRE 481 DH P DP +++ +S+ + HC AG+GRT F+V+ ++ ++ Sbjct: 210 DHFRPDDPD-----VDKFLEFYKSLPKDAWLHYHCYAGMGRTTIFMVMHDILKNAKD 261 Score = 32.7 bits (73), Expect = 0.46, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 19/54 (35%), Gaps = 10/54 (18%) Query: 423 WPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 476 WP + +F+ + HC AG GRT ++ + ++ Sbjct: 511 WP------SAANIDEFINFTRTMPANAWLH----FHCQAGAGRTTAYMAMYDMM 554 >1YN9-A nrPDB Length = 169 Score = 33.5 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 32/84 (38%), Gaps = 9/84 (10%) Query: 428 VPSDPGGVLDFLEEVHHKQESIMDAGP---VVVHCSAGIGRTGTFIVIDILIDIIREKGV 484 VP ++E + + P V VHC+ GI RTG + ++ G+ Sbjct: 86 VPGQTLPPESIVQEFIDTVKEFTEKCPGMLVGVHCTHGINRTGYMV----CRYLMHTLGI 141 Query: 485 --DCDIDVPKTIQMVRSQRSGMVQ 506 ID + + + +R VQ Sbjct: 142 APQEAIDRFEKARGHKIERQNYVQ 165 >5GQY-A nrPDB Length = 793 Score = 33.1 bits (74), Expect = 0.35, Method: Composition-based stats. Identities = 31/137 (22%), Positives = 52/137 (37%), Gaps = 16/137 (11%) Query: 48 NGAVTHIKIQNTGDY-------YDLYGGEKFATLAELVQY---YMEHHGQLKEKNGDVIE 97 +G V +I+N+ + Y Y + T + +V Y H + EK + Sbjct: 207 SGTVYKYEIKNSEGHIYEKSDPYGFYREVRPNTASIVVDIDNIYQWHDEEWLEKRRNSDP 266 Query: 98 LKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDK 157 LK P++ + W HG AEK+ G+ +V S+ +PG LS +K Sbjct: 267 LKQPVSVYEVHLGSWLHGS----SAEKMPLLNGEADPVIV--SEWNPGARFLSYYELAEK 320 Query: 158 GESNDGKSKVTHVMIRC 174 TH+ + Sbjct: 321 LIPYVKDMGYTHIELLP 337 >4B04-A nrPDB Length = 160 Score = 33.1 bits (74), Expect = 0.39, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 41/123 (33%), Gaps = 38/123 (30%) Query: 398 LRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGV------------------LDFL 439 LR L ++ V + R W G P G+ + F Sbjct: 24 LRRLGITHVLNASHSR---------W--RGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQ 72 Query: 440 EEVHHKQESIMDAG-PVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR 498 ++ G ++VH + G+ R+ T ++ +++ + + + I+ V+ Sbjct: 73 TAADFIHRALSQPGGKILVHSAVGVSRSATLVLAYLMLYH--------HLTLVEAIKKVK 124 Query: 499 SQR 501 R Sbjct: 125 DHR 127 >5GTJ-A nrPDB Length = 181 Score = 32.7 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 41/123 (33%), Gaps = 38/123 (30%) Query: 398 LRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGV------------------LDFL 439 LR L ++ V + R W G P G+ + F Sbjct: 45 LRRLGITHVLNASHSR---------W--RGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQ 93 Query: 440 EEVHHKQESIMDAG-PVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR 498 ++ G ++VH + G+ R+ T ++ +++ + + + I+ V+ Sbjct: 94 TAADFIHRALSQPGGKILVHSAVGVSRSATLVLAYLMLYH--------HLTLVEAIKKVK 145 Query: 499 SQR 501 R Sbjct: 146 DHR 148 >1ZZW-A nrPDB Length = 149 Score = 32.3 bits (72), Expect = 0.66, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 5/44 (11%) Query: 455 VVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR 498 +++HC AG+ R+ T IVI L+ R D K ++ R Sbjct: 86 LLIHCQAGVSRSAT-IVIAYLMKHTRMTMT----DAYKFVKGKR 124 >2OUD-A nrPDB Length = 177 Score = 32.3 bits (72), Expect = 0.67, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 5/44 (11%) Query: 455 VVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR 498 +++HC AG+ R+ T IVI L+ R D K ++ R Sbjct: 90 LLIHCQAGVSRSAT-IVIAYLMKHTRMTMT----DAYKFVKGKR 128 >3ZID-A nrPDB Length = 373 Score = 32.0 bits (71), Expect = 0.69, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 47/134 (35%), Gaps = 22/134 (16%) Query: 193 LVEHYKKNPMVETLGTVLQ--LKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEE 250 L ++Y K + T+ L + AA+ V L + K KQGFWE Sbjct: 30 LAKYYSKQRFPSRVETIAINTAINDLKELKFTAAKDRLHVPNLHGVGANRSKGKQGFWEN 89 Query: 251 FETL-----QQQECKLLYSRKE---------GQRQENKNKNRYKNILPFDHTRVVLHDGD 296 E + ++ + L++ ++ K RYKN T V + Sbjct: 90 QEMILEEIEKRGDFDLIFVMTSVSGGTGSSFSPLMIHELKKRYKN-----ATIVPIAVLP 144 Query: 297 PNEPVSDYI-NANI 309 E + Y+ NA Sbjct: 145 FREEGTIYLQNAAF 158 >4JMK-A nrPDB Length = 152 Score = 32.0 bits (71), Expect = 0.74, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 27/52 (51%), Gaps = 5/52 (9%) Query: 447 ESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR 498 ++ + + V+VH AGI R+ T I I ++ + G+ D D + ++ R Sbjct: 76 KAKLSSCQVIVHSLAGISRSAT-IAIAYIMKTM---GMSSD-DAYRFVKDRR 122 >5T2N-A nrPDB Length = 296 Score = 32.0 bits (71), Expect = 0.78, Method: Composition-based stats. Identities = 25/155 (16%), Positives = 57/155 (36%), Gaps = 26/155 (16%) Query: 132 HGSFLVRESQSHPGDFV-------LSVR-TGDDKGESNDGKSKVTHVMIRCQELKYDVGG 183 GSF++R +++ G V S++ DK + +S I + + Sbjct: 17 EGSFILR-IRNNNGMRVGYLTELIFSIKLHNKDKSILENIQSTWKVGKITNNGDQAVMLR 75 Query: 184 GERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKV 243 RF+ L +++H++K P++ T+ ++ + E + + Sbjct: 76 VSRFEDLKVIIDHFEKYPLI---------------TQKLGDY--KLFKQAYSVMENKEHL 118 Query: 244 KQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNR 278 K+ +E ++ + L + E +K R Sbjct: 119 KENGIKELVRIKAKMNWGLTDELKKAFPEIISKER 153 >2R0B-A nrPDB Length = 154 Score = 31.6 bits (70), Expect = 0.89, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 8/68 (11%) Query: 453 GPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR---SQRSGMVQTEA 509 G V+VH +AGI R+ F++ I+ G+ D +Q R + +G V Sbjct: 91 GKVLVHGNAGISRSAAFVIAYIM----ETFGMKYR-DAFAYVQERRFCINPNAGFVHQLQ 145 Query: 510 QYRFIYMA 517 +Y IY+A Sbjct: 146 EYEAIYLA 153 >2Q47-A nrPDB Length = 151 Score = 31.6 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 29/88 (32%), Gaps = 19/88 (21%) Query: 420 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII 479 F PDH + +LD PV++HC G RTG + + + Sbjct: 72 FVNIPDHKIRMALKVLLD------------EKNHPVLIHCKRGKHRTGCLVG---CLRKL 116 Query: 480 REKGVDCDIDVPK----TIQMVRSQRSG 503 ++ + D + V QR Sbjct: 117 QKWCLTSIFDEYQRFAAAKARVSDQRFM 144 >3LJ8-A nrPDB Length = 146 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 30/66 (45%), Gaps = 8/66 (12%) Query: 418 YHFRTWP--DHGVPSDPGGVLDFL-EEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDI 474 +H++ P DH + F E + E++ V+VHC AG+ R+ T + + Sbjct: 49 FHYKQIPISDH----WSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVT-VTVAY 103 Query: 475 LIDIIR 480 L+ + Sbjct: 104 LMQKLH 109 >4Y5W-A nrPDB Length = 549 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 6/82 (7%) Query: 9 PNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLS-VRRNG----AVTHIKIQNTGDYY 63 I+ +LLL DG+FL R S S G T++ V R + +I+ + D Sbjct: 431 GFISKQYVTSLLLNEP-DGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLS 489 Query: 64 DLYGGEKFATLAELVQYYMEHH 85 G++ LA+L Y + Sbjct: 490 IRSLGDRIRDLAQLKNLYPKKP 511 >5NCR-A nrPDB Length = 181 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 31/85 (36%), Gaps = 7/85 (8%) Query: 442 VHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCD----IDVPKTIQMV 497 V + P +VH AG+ R+G + ++ + E + KT + Sbjct: 95 VKLLARLEAEQKPTLVHSVAGVNRSGAAAMGYVMHKRLAENPTMTQPARFVYFLKTYYEI 154 Query: 498 RSQRSGMVQTEAQYRFIYMAVQHYI 522 R R ++ F Y ++ ++ Sbjct: 155 RDLRGAFLENAN---FRYQLIKMFV 176 >3E6P-L nrPDB Length = 158 Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 36/96 (37%), Gaps = 5/96 (5%) Query: 181 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLK-QPLNTTRINAAEIESRVREL--SKLA 237 + + F+S LVE++ +NP + G + +P + + E V E L Sbjct: 40 LSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLD 99 Query: 238 ETTDKVKQG--FWEEFETLQQQECKLLYSRKEGQRQ 271 E +D+ +G E++T G R Sbjct: 100 EDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRP 135 >4MBB-A nrPDB Length = 184 Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 6/63 (9%) Query: 426 HGVPSDPGGVLDFLEEVHHKQESIMDAGPVV-VHCSAGIGRTGTFIVIDILIDIIREKGV 484 H VP D + F V+ + D ++ VH + G+ RTG I +I +GV Sbjct: 96 HQVPDD-ETIFKFKHAVNGFLKENKDNDKLIGVHSTHGLNRTGYLI----CRYLIDVEGV 150 Query: 485 DCD 487 D Sbjct: 151 RPD 153 >5WB5-A nrPDB Length = 219 Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 40/96 (41%), Gaps = 9/96 (9%) Query: 489 DVPKTIQMVRSQRS-GMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKY 547 V + M+R + ++T +QY F V + + E+ +K+ G + N+ Sbjct: 54 SVEEFFVMLRYMKPLHALRTSSQYHFFQEGV--------KPMWEDPANKKGGKLWVNLDI 105 Query: 548 SLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENV 583 + A+ S + + AE + D + +ENV Sbjct: 106 TSANGRSSNNNTSGTSAADGSAAEAKTDLDKAWENV 141 >4NZQ-A nrPDB Length = 557 Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 36/96 (37%), Gaps = 5/96 (5%) Query: 181 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLK-QPLNTTRINAAEIESRVREL--SKLA 237 + + F+S LVE++ +NP + G + +P + + E V E L Sbjct: 180 LSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLD 239 Query: 238 ETTDKVKQG--FWEEFETLQQQECKLLYSRKEGQRQ 271 E +D+ +G E++T G R Sbjct: 240 EDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRP 275 >2ESB-A nrPDB Length = 188 Score = 30.8 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 25/63 (39%), Gaps = 5/63 (7%) Query: 418 YHFRTWPDHGVPSDPGGVL-DFLEEV-HHKQESIMDAGPVVVHCSAGIGRTGTFIVIDIL 475 + P V P L DF + + H M G ++HC+AG+ R+ + ++ Sbjct: 64 IQYMQVP---VADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM 120 Query: 476 IDI 478 Sbjct: 121 KYH 123 >3NXP-A nrPDB Length = 424 Score = 30.8 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 36/96 (37%), Gaps = 5/96 (5%) Query: 181 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLK-QPLNTTRINAAEIESRVREL--SKLA 237 + + F+S LVE++ +NP + G + +P + + E V E L Sbjct: 47 LSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLD 106 Query: 238 ETTDKVKQGFWE--EFETLQQQECKLLYSRKEGQRQ 271 E +D+ +G E++T G R Sbjct: 107 EDSDRAIEGATATSEYQTFFNPATFGSGEADCGLRP 142 >4KYQ-A nrPDB Length = 208 Score = 30.8 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 12/22 (54%), Positives = 13/22 (59%), Gaps = 1/22 (4%) Query: 451 DAGPVVVHCSAGIGRT-GTFIV 471 G V VHCSAG+GR G I Sbjct: 111 GKGRVYVHCSAGLGRAPGVSIA 132 >2R51-A nrPDB Length = 340 Score = 30.8 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 34/176 (19%), Positives = 62/176 (35%), Gaps = 17/176 (9%) Query: 118 SGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQEL 177 S K AE + K FL + ++ G LS++ + + E K + I EL Sbjct: 25 SRKRAEHKTEDGKKEKYFLFYDGETVSGKVSLSLKNPNKRLEHQGIKIEF----IGQIEL 80 Query: 178 KYDVGGGERFDSLT-DLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESR------- 229 YD G F SL DL + +++P + ++ R Sbjct: 81 YYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYES--YTGQNVKLRYFLRATI 138 Query: 230 VRELSKLAETTDKVKQGFWEEFETLQQ--QECKLLYSRKEGQRQENKNKNRYKNIL 283 R L+ + + D V + L + + + + NK+K K+++ Sbjct: 139 SRRLNDVVKEMDIVVHTLST-YPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVI 193 >3G5W-A nrPDB Length = 318 Score = 30.4 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 20/140 (14%), Positives = 42/140 (30%), Gaps = 18/140 (12%) Query: 44 SVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 + NG V I TL + ++ + +G ++ + Sbjct: 24 TFAFNGQVPAPLIHVMEGDDVTVNVTNMTTLPHTIHWHGMLQRGTWQSDGVPHATQHAIE 83 Query: 104 C---------ADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHP------GDFV 148 A+P W+H H++ E + +G G +V P D++ Sbjct: 84 PGDTFTYKFKAEPAGTMWYHCHVNVNEHVTM---RGMWGPLIVEPKNPLPIEKTVTKDYI 140 Query: 149 LSVRTGDDKGESNDGKSKVT 168 L + + G+ + Sbjct: 141 LMLSDWVSSWANKPGEGGIP 160 >2G2B-A nrPDB Length = 150 Score = 30.4 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 14/28 (50%) Query: 339 NDFWRMVFQENSRVIVMTTKEVERGKSK 366 DF RM+ + S ++ M E+ + K Sbjct: 107 PDFLRMMLGKRSAILKMILMYEEKAREK 134 >2J16-A nrPDB Length = 182 Score = 30.4 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 39/106 (36%), Gaps = 13/106 (12%) Query: 381 GVMRVRNVKESAAHDYTLRELK-----LSKVGQGNTER---TVWQYHFRTWPDHGVPSDP 432 G + V K + T++EL ++ + N R +YH W +H D Sbjct: 43 GPLLVLPEKIYLYSEPTVKELLPFDVVINVAEEANDLRMQVPAVEYHHYRW-EH----DS 97 Query: 433 GGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDI 478 LD + +++HC G+ R+ T I+ I+ Sbjct: 98 QIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYH 143 >5T8D-A nrPDB Length = 296 Score = 30.0 bits (66), Expect = 2.9, Method: Composition-based stats. Identities = 21/156 (13%), Positives = 54/156 (34%), Gaps = 23/156 (14%) Query: 128 EKGKHGSFLV-----RESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVG 182 +G G +++ R + F +++ DK + +S +I Sbjct: 16 AEGSFGLYIINRNRGRIRYTTRLKFTITL-HNKDKSILENIQSTWKVGIIANNGDNAVSL 74 Query: 183 GGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDK 242 RF+ L +++H++K P++ T+ ++ + E + Sbjct: 75 IVTRFEDLKVIIDHFEKYPLI---------------TQKLGDY--KLFKQAFSVMENKEH 117 Query: 243 VKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNR 278 +K+ +E ++ + L + N ++ R Sbjct: 118 LKENGIKELVRIKAKMNWGLTDELKKAFPGNISRER 153 >4Y2E-A nrPDB Length = 149 Score = 29.6 bits (65), Expect = 4.1, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 22/45 (48%), Gaps = 7/45 (15%) Query: 436 LDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 480 + F++E K+ V+VH AGI R+ T + + L+ + Sbjct: 75 ISFIDEARSKKCG------VLVHSLAGISRSVT-VTVAYLMQKMN 112 >4PO6-A nrPDB Length = 567 Score = 29.3 bits (64), Expect = 4.9, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 27/80 (33%), Gaps = 12/80 (15%) Query: 8 HPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAV---------THIKIQN 58 H + + L R DG +L S S+P L+V + I+ Sbjct: 432 HGPLLEPFVQAKL--RPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQ 489 Query: 59 TGDYYDL-YGGEKFATLAEL 77 + L G F ++ EL Sbjct: 490 QDGAFVLEGWGRSFPSVREL 509 >4A5P-A nrPDB Length = 383 Score = 29.3 bits (64), Expect = 5.2, Method: Composition-based stats. Identities = 25/165 (15%), Positives = 60/165 (36%), Gaps = 25/165 (15%) Query: 140 SQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM--------IRCQELKYDVGGGERFDSLT 191 S++ P L + ++K +ND + + + +R + Y + D + Sbjct: 55 SETVP----LILLFAENKINANDMEGLIERIRSQFFIDYGVRLPTILYRTSNELKVDDIV 110 Query: 192 DLVE---------HYKKNPMVETLGTVLQLKQPLNTTRINAAEIE----SRVRELSKLAE 238 L+ ++ K + + G + L P+ +T N I S L+ + Sbjct: 111 LLINEVRADSFNIYFDKVCITDENGDIDALGIPVVSTSYNERVISWVDVSYTENLTNIDA 170 Query: 239 TTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNIL 283 + F+ + ++ +E + ++ +NRY ++L Sbjct: 171 KIKSAQDEFYHQLSQALLNNINEIFGIQETKNMLDQFENRYPDLL 215 >2BN8-A nrPDB Length = 87 Score = 28.9 bits (63), Expect = 6.7, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 15/34 (44%) Query: 545 IKYSLADQTSGDQSPLPPCTPTPPCAEMREDSAR 578 +K L Q S +P P PP ++ DS R Sbjct: 8 MKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFR 41 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.134 0.415 Lambda K H 0.267 0.0411 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,421,526 Number of Sequences: 36641 Number of extensions: 1008519 Number of successful extensions: 4287 Number of sequences better than 10.0: 170 Number of HSP's better than 10.0 without gapping: 216 Number of HSP's successfully gapped in prelim test: 80 Number of HSP's that attempted gapping in prelim test: 3222 Number of HSP's gapped (non-prelim): 434 length of query: 593 length of database: 10,336,785 effective HSP length: 103 effective length of query: 490 effective length of database: 6,562,762 effective search space: 3215753380 effective search space used: 3215753380 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.5 bits)