BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q05871 (280 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4ZDC-A nrPDB 578 e-166 5ZAI-A nrPDB 58 4e-09 5VE2-A nrPDB 57 8e-09 2DUB-A nrPDB 49 2e-06 5WYB-B nrPDB 48 4e-06 4JFC-A nrPDB 47 9e-06 4FZW-A nrPDB 47 1e-05 2HW5-A nrPDB 45 4e-05 5JBW-A nrPDB 41 6e-04 5YLO-A nrPDB 41 7e-04 4FZW-C nrPDB 40 8e-04 3MOY-A nrPDB 40 0.002 3HE2-A nrPDB 39 0.003 3H81-A nrPDB 36 0.015 2PPY-A nrPDB 35 0.026 4JWV-A nrPDB 35 0.037 4JCS-A nrPDB 34 0.059 5Z7R-A nrPDB 34 0.074 3T8B-A nrPDB 34 0.090 4JSB-A nrPDB 33 0.18 2WTB-A nrPDB 30 1.5 4HC8-A nrPDB 28 5.3 4HDT-A nrPDB 27 6.8 3SWN-B nrPDB 27 9.4 >4ZDC-A nrPDB Length = 300 Score = 578 bits (1491), Expect = e-166, Method: Compositional matrix adjust. Identities = 279/280 (99%), Positives = 280/280 (100%) Query: 1 MSQEIRQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQ 60 MSQEIRQNEKISYRIEGPFFIIHL+NPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQ Sbjct: 21 MSQEIRQNEKISYRIEGPFFIIHLINPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQ 80 Query: 61 SSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLN 120 SSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLN Sbjct: 81 SSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLN 140 Query: 121 GPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMF 180 GPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMF Sbjct: 141 GPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMF 200 Query: 181 NKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNH 240 NKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNH Sbjct: 201 NKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNH 260 Query: 241 IDAFNKANSVEVNESLKYWVDGEPLKRFRQLGSKQRKHRL 280 IDAFNKANSVEVNESLKYWVDGEPLKRFRQLGSKQRKHRL Sbjct: 261 IDAFNKANSVEVNESLKYWVDGEPLKRFRQLGSKQRKHRL 300 >5ZAI-A nrPDB Length = 259 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 57/212 (26%), Positives = 84/212 (39%), Gaps = 14/212 (6%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSS 68 E I + EG F I L PD LNAL + L + A+ + ++ II G+ F + Sbjct: 4 ETIETKKEGNLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKGKAFCA 63 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 GAD P+E K F + + D SK I +NG A+G Sbjct: 64 GADITQF-------NQLTPAEAWK----FSKKGREIMDKIEALSKPTIAMINGYALGGGL 112 Query: 129 ALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDI 188 L CDI + ++ L P NLG+ G T L G E +M Sbjct: 113 ELALACDIRIA-AEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKD 171 Query: 189 MCENGFISKNFNMPSSNAEAFNAKVLEELREK 220 + G + N +P +N E K+ E++ +K Sbjct: 172 AEKYGLV--NRVVPLANLEQETRKLAEKIAKK 201 >5VE2-A nrPDB Length = 275 Score = 57.0 bits (136), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 47/211 (22%), Positives = 91/211 (43%), Gaps = 21/211 (9%) Query: 27 PDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQGDDTNKY 86 P+ NAL E Y L + LE ++ + + ++ ++G F++G D D N Sbjct: 43 PELKNALNRELYAALADELERSNHDDQIRAVLLTANGDTFTAGNDLD-------DFINPV 95 Query: 87 PSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVYL 146 + V F+ A + ++ +NGPAIG+ ++ CD+VY+ + Sbjct: 96 EESGTPSVIRFL-------KAISECETPIVVAVNGPAIGVGLTMLLHCDMVYA-SKSARF 147 Query: 147 LYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPSSNA 206 PF ++GL+ E +++ LPL G + ++ + G +++ F A Sbjct: 148 RAPFTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAGLVTRVFEDDVLVA 207 Query: 207 EAFNAKVLEELREKVKGLYLPSCLGMKKLLK 237 E+ ++ E+V L S K+L++ Sbjct: 208 ESL------KIAEQVASLAPNSVKQSKRLIR 232 >2DUB-A nrPDB Length = 261 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 47/190 (24%), Positives = 77/190 (40%), Gaps = 14/190 (7%) Query: 21 IIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQG 80 +I L P LNAL L + LE + + V ++ + F++GAD K + Sbjct: 20 LIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTF 79 Query: 81 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSI 140 D + K++S++ D + K +I +NG A+G L +CDI+Y+ Sbjct: 80 QDCY-----SGKFLSHW--------DHITRIKKPVIAAVNGYALGGGCELAMMCDIIYA- 125 Query: 141 NDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFN 200 +K P LG I G T L G + E ++ + G +SK F Sbjct: 126 GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFP 185 Query: 201 MPSSNAEAFN 210 + + EA Sbjct: 186 VETLVEEAIQ 195 >5WYB-B nrPDB Length = 280 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 44/192 (22%), Positives = 80/192 (41%), Gaps = 20/192 (10%) Query: 10 KISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFFSS 68 K++ G +I + +P N + + I L +L+E +R+ D+Y ++ G +FFS+ Sbjct: 18 KLTVEKHGHTALITINHPP-ANTWDRDSLIGLRQLIEHLNRDDDIYALVVTGQGPKFFSA 76 Query: 69 GADFKGIA---KAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIG 125 GAD A KA+ + + E + + +F V I +NG A+G Sbjct: 77 GADLNMFADGDKARAREMARRFGEAFEALRDF--------------RGVSIAAINGYAMG 122 Query: 126 LSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFK 185 CDI + + + P A +GL+ G T +LP G ++ N+ Sbjct: 123 GGLECALACDIRIA-ERQAQMALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILCNERVD 181 Query: 186 YDIMCENGFISK 197 + G + + Sbjct: 182 AETALRIGLVEQ 193 >4JFC-A nrPDB Length = 281 Score = 47.0 bits (110), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 43/182 (23%), Positives = 84/182 (46%), Gaps = 9/182 (4%) Query: 16 EGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGI 75 EG I+ L NP+ NAL E Y E L A+ N ++ +I G F +G + + + Sbjct: 32 EGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVFCAGGNLQRL 91 Query: 76 AKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCD 135 +A + + +++ + + N++ D+ + K +I + G A G +L CD Sbjct: 92 -QANRREAPEVQAQSIEGLHNWI-------DSIRTYPKPVIAAVEGAAAGAGFSLALACD 143 Query: 136 IVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFI 195 V + ++ V+++ ++ +GL +GG + SL E LM + + + G + Sbjct: 144 FVVAASNAVFVM-SYSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLV 202 Query: 196 SK 197 +K Sbjct: 203 NK 204 >4FZW-A nrPDB Length = 258 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 45/182 (24%), Positives = 74/182 (40%), Gaps = 18/182 (9%) Query: 20 FIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQ 79 ++ L P NAL + L LE A + + +I + RFF++GAD +A+ Sbjct: 16 LLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFAAGADLNEMAE-- 73 Query: 80 GDDTNKYPSETSK--WVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIV 137 D ++T W AF +K LI +NG A+G L LCD+V Sbjct: 74 -KDLAATLNDTRPQLWAR---------LQAF---NKPLIAAVNGYALGAGCELALLCDVV 120 Query: 138 YSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISK 197 + + + L P LG++ G T L G + + ++ + + G +S Sbjct: 121 VAGENARFGL-PEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSD 179 Query: 198 NF 199 F Sbjct: 180 VF 181 >2HW5-A nrPDB Length = 286 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 42/177 (23%), Positives = 72/177 (40%), Gaps = 14/177 (7%) Query: 21 IIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQG 80 +I L P LNAL L + L++ + + V ++ + F++GAD K + Sbjct: 45 LIQLNRPKALNALCDGLIDELNQALKIFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSF 104 Query: 81 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSI 140 D +SK++ ++ D + K +I +NG A G L +CDI+Y+ Sbjct: 105 QDCY-----SSKFLKHW--------DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA- 150 Query: 141 NDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISK 197 +K P +G I G T L G + E ++ + G +SK Sbjct: 151 GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSK 207 >5JBW-A nrPDB Length = 260 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 41/167 (24%), Positives = 61/167 (36%), Gaps = 13/167 (7%) Query: 17 GPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFFSSGADFKGI 75 GP I + NA+ LGEL+ +RDV +I +G + F +GAD K Sbjct: 12 GPIEIWTIDGESRRNAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGADLKER 71 Query: 76 AKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCD 135 A D+ + + A K V I +NG A+G L CD Sbjct: 72 ATMAEDEVRAFLDGLRRTFR-----------AIEKSDCVFIAAINGAALGGGTELALACD 120 Query: 136 IVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNK 182 + + L LG+I GG T L G + ++ + Sbjct: 121 LRVA-APAAELGLTEVKLGIIPGGGGTQRLARLVGPGRAKDLILTAR 166 >5YLO-A nrPDB Length = 271 Score = 40.8 bits (94), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 37/189 (19%), Positives = 71/189 (37%), Gaps = 13/189 (6%) Query: 11 ISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGA 70 + R+E + L P NAL+ L L+ +R+ V ++ SGR F +GA Sbjct: 7 LQTRVEAGIAWLVLNRPQQRNALDIPTLEALHVRLDACERDPAVRAVVLGGSGRSFCAGA 66 Query: 71 DFKGIAKAQGDDTNKYPSETSKW--VSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 D A A+ + E+ W ++ + ++ D K + +NG A+G Sbjct: 67 DLAEWAAAEA----RGELESYGWTEAAHALMGRLHALD------KPTVAAVNGSAVGAGM 116 Query: 129 ALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDI 188 L CD + + + + + G + LP G+ L ++ + + Sbjct: 117 DLALCCDFRIAAASARF-KAGYTGMAYCPDAGASWHLPRLLGSEAAKRLLFLDEAWSAER 175 Query: 189 MCENGFISK 197 G + + Sbjct: 176 ALGAGLVGE 184 >4FZW-C nrPDB Length = 274 Score = 40.4 bits (93), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 50/189 (26%), Positives = 77/189 (40%), Gaps = 12/189 (6%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSS 68 E I +E + L P+ LN+ E + L E L+ +R+ + ++ +GR F + Sbjct: 15 EFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCA 74 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVAR--NVYVTDAFIKHSKVLICCLNGPAIGL 126 G D +D N P+ + + V R N V K K +IC +NG A G Sbjct: 75 GQDL--------NDRNVDPTGPAPDLGMSVERFYNPLVR-RLAKLPKPVICAVNGVAAGA 125 Query: 127 SAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKY 186 A L DIV + +++ F+ LGLI + G T LP G + Sbjct: 126 GATLALGGDIVIAARSAKFVMA-FSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSA 184 Query: 187 DIMCENGFI 195 + E G I Sbjct: 185 EQAHEWGMI 193 >3MOY-A nrPDB Length = 263 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 51/247 (20%), Positives = 101/247 (40%), Gaps = 40/247 (16%) Query: 21 IIHLMNPDNLNALEGEDYIYLGELLELA---DRNRDVYFTIIQSSGRFFSSGADFKGIAK 77 +I L PD LNAL + E+L+ A D + ++ ++ S R F++GAD Sbjct: 22 LIRLDRPDALNAL---NQTLEAEVLDAARDFDADLEIGAIVVTGSERAFAAGADI----- 73 Query: 78 AQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIV 137 A+ + + +S + D+ + K ++ + G A+G L LCD+V Sbjct: 74 AEMVTLTPHQARERNLLSGW--------DSLTQVRKPIVAAVAGYALGGGCELAMLCDLV 125 Query: 138 YSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISK 197 + D P LG++ G T L G + + + + G +S+ Sbjct: 126 IA-ADTARFGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVGLVSR 184 Query: 198 NFNMPSSNAEAFNAKVLEE---LREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVNE 254 +P+++ +L+E + +++ + P+ +K DA N+A ++ Sbjct: 185 --IVPAAD-------LLDEALAVAQRIARMSRPAGRAVK--------DAINEAFERPLSA 227 Query: 255 SLKYWVD 261 ++Y D Sbjct: 228 GMRYERD 234 >3HE2-A nrPDB Length = 264 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 41/195 (21%), Positives = 72/195 (36%), Gaps = 20/195 (10%) Query: 19 FFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKA 78 I L P+ NAL + L + + A + ++ G F +GAD G A A Sbjct: 31 VLTIELQRPERRNALNSQLVEELTQAIRKAG-DGSARAIVLTGQGTAFCAGADLSGDAFA 89 Query: 79 QGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVY 138 YP R + + A ++ +NGPAIG L CD+ Sbjct: 90 -----ADYPD-----------RLIELHKAMDASPMPVVGAINGPAIGAGLQLAMQCDLRV 133 Query: 139 SINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKN 198 D + +P + GL + + L G L+ + +I G ++ Sbjct: 134 VAPD-AFFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEIALHTGMANRI 192 Query: 199 FNMPSSNAEAFNAKV 213 + ++A+A+ A++ Sbjct: 193 GTL--ADAQAWAAEI 205 >3H81-A nrPDB Length = 278 Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust. Identities = 40/186 (21%), Positives = 69/186 (37%), Gaps = 32/186 (17%) Query: 21 IIHLMNPDNLNALEGEDYIYLGELLELA---DRNRDVYFTIIQSSGRFFSSGADFKGIAK 77 II L P LNAL + + E+ A D + D+ II S + F++GAD K +A Sbjct: 37 IITLNRPQALNALNSQ---VMNEVTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMA- 92 Query: 78 AQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKV------LICCLNGPAIGLSAALV 131 + + + D F K+ I + G A+G L Sbjct: 93 ------------------DLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELA 134 Query: 132 ALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCE 191 +CD++ + D P LG++ G + L G + ++ + Sbjct: 135 MMCDVLIA-ADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAER 193 Query: 192 NGFISK 197 +G +S+ Sbjct: 194 SGLVSR 199 >2PPY-A nrPDB Length = 265 Score = 35.4 bits (80), Expect = 0.026, Method: Compositional matrix adjust. Identities = 31/148 (20%), Positives = 57/148 (38%), Gaps = 12/148 (8%) Query: 53 DVYFTIIQSS-GRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKH 111 D+ I+ S +FFS+GAD N S ++ + F D + Sbjct: 52 DIKVVIVMSDVPKFFSAGADI-----------NFLRSADPRFKTQFCLFCNETLDKIARS 100 Query: 112 SKVLICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGT 171 +V I CL G +G + CD+ + ++ + P +LG++ G T L G Sbjct: 101 PQVYIACLEGHTVGGGLEMALACDLRFMGDEAGKIGLPEVSLGVLAGTGGTQRLARLIGY 160 Query: 172 NTTYECLMFNKPFKYDIMCENGFISKNF 199 + + + + E G +++ F Sbjct: 161 SRALDMNITGETITPQEALEIGLVNRVF 188 >4JWV-A nrPDB Length = 278 Score = 35.0 bits (79), Expect = 0.037, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 3/69 (4%) Query: 11 ISYRIEGPFFIIHLMNPDNLNALEGE-DYIYLGELLELADRNRDVYFTIIQSSG-RFFSS 68 I +RIEG + L P LNA+ E D + L E+ + N D++ ++ + G + F Sbjct: 26 IDFRIEGHVAHVRLNRPQGLNAITQEMDDLLLDAWTEV-NANSDIWAVVLSAEGEKAFCI 84 Query: 69 GADFKGIAK 77 GAD G A+ Sbjct: 85 GADVSGGAE 93 >4JCS-A nrPDB Length = 286 Score = 34.3 bits (77), Expect = 0.059, Method: Compositional matrix adjust. Identities = 36/164 (21%), Positives = 61/164 (37%), Gaps = 9/164 (5%) Query: 113 KVLICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTN 172 + +I ++GPA G AL DIV + + + + LGL+ + G LP G Sbjct: 120 RPVIAAVDGPAFGAGFALSLTADIVLA-SPRARFSMAYLRLGLVPDLGALYLLPRAVGLQ 178 Query: 173 TTYECLMFNKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGM 232 E + + + G + M +EA + E V+ P+ L + Sbjct: 179 RAKELMFSTRELDAEEAHRLGLV-----MEVHESEALEQRAREIAESLVQA--APTALAL 231 Query: 233 KKLLKSNHIDAFNKAN-SVEVNESLKYWVDGEPLKRFRQLGSKQ 275 K + +D+ + S+E + EP L SKQ Sbjct: 232 TKAALNVSLDSDEQTMFSLEAASQAAAFSTKEPRAAIEALLSKQ 275 >5Z7R-A nrPDB Length = 267 Score = 33.9 bits (76), Expect = 0.074, Method: Compositional matrix adjust. Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 23/188 (12%) Query: 16 EGPFFIIHLMNPDNLNALEGE-----DYIYLGELLELADRNRDVYFTIIQSSG-RFFSSG 69 EG ++ + P LNAL + DY+ +GE+ + + +V I+ +G + F +G Sbjct: 11 EGKVAVVTINRPKALNALNSDTLKEMDYV-IGEI----ENDSEVLAVILTGAGEKSFVAG 65 Query: 70 ADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAA 129 AD ++ + N + N V R + + + K +I +NG A+G Sbjct: 66 ADI-----SEMKEMNTIEGRKFGILGNKVFRRLELLE------KPVIAAVNGFALGGGCE 114 Query: 130 LVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIM 189 + CDI + ++ + P LG+ G T L G + + + K D Sbjct: 115 IAMSCDIRIASSNARF-GQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEA 173 Query: 190 CENGFISK 197 G ++K Sbjct: 174 LRIGLVNK 181 >3T8B-A nrPDB Length = 334 Score = 33.9 bits (76), Expect = 0.090, Method: Compositional matrix adjust. Identities = 19/83 (22%), Positives = 35/83 (42%) Query: 113 KVLICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTN 172 KV+IC +NG A G +L +CD+ + + A++G G + L + G Sbjct: 168 KVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQK 227 Query: 173 TTYECLMFNKPFKYDIMCENGFI 195 E + + + M + G + Sbjct: 228 FAREIFFLGRTYTAEQMHQMGAV 250 >4JSB-A nrPDB Length = 296 Score = 32.7 bits (73), Expect = 0.18, Method: Compositional matrix adjust. Identities = 49/182 (26%), Positives = 72/182 (39%), Gaps = 24/182 (13%) Query: 11 ISYRIEGPFFIIHLMNPDNLNALEGEDYIYL---GELLELADRNRDVYFTIIQSSGRFFS 67 ++ I+G I L P NA+ G + L G L A V +I G FS Sbjct: 38 LTLTIDGEVARITLSRPHRRNAMTGRMWTELARIGHTLPQA-----VRIVVITGEGPTFS 92 Query: 68 SGADFK--GIAKAQGDDT-----NKYPSETS---KWVSNFVARNVYVTDAFIKHSKVLIC 117 SG D K G+ T + P+ T+ + ++++ +++ A I V I Sbjct: 93 SGIDLDMFQAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLWLRRADI----VSIA 148 Query: 118 CLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYE- 176 + G AIG L CDI ++D L LGL+ + T L G N E Sbjct: 149 AVRGHAIGAGFQLALSCDIRI-LSDTAQLCMKEPALGLVPDLTGTQPLVELVGVNRAIEL 207 Query: 177 CL 178 CL Sbjct: 208 CL 209 >2WTB-A nrPDB Length = 725 Score = 29.6 bits (65), Expect = 1.5, Method: Compositional matrix adjust. Identities = 43/167 (25%), Positives = 68/167 (40%), Gaps = 10/167 (5%) Query: 21 IIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQG 80 +I L+NP +N+L + L E A DV +I + FS G D G + Q Sbjct: 20 VITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQK 78 Query: 81 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSI 140 + K P + +++ ++ +TD K + ++G A+G L C S Sbjct: 79 GNV-KEPK------AGYISIDI-ITDLLEAARKPSVAAIDGLALGGGLELAMACHARIS- 129 Query: 141 NDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 187 L P LG+I G T LP G E ++ +KP K + Sbjct: 130 APAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAE 176 >4HC8-A nrPDB Length = 255 Score = 27.7 bits (60), Expect = 5.3, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Query: 8 NEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFS 67 ++ +SY + +I M+ +NAL L ++ ADR+ DV +I +GR FS Sbjct: 4 SDPVSYTRKDSIAVIS-MDDGKVNALGPAMQQALNAAIDNADRD-DVGALVITGNGRVFS 61 Query: 68 SGADFK 73 G D K Sbjct: 62 GGFDLK 67 >4HDT-A nrPDB Length = 353 Score = 27.3 bits (59), Expect = 6.8, Method: Compositional matrix adjust. Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 4/84 (4%) Query: 7 QNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RF 65 +NE + +EG ++ L P +N+L + E L + + V ++ +G R Sbjct: 7 KNEDVLVNVEGGVGLLTLNRPKAINSLTHGMVTTMAERLAAWENDDSVRAVLLTGAGERG 66 Query: 66 FSSGADFKGI---AKAQGDDTNKY 86 +G D I AKA G + ++ Sbjct: 67 LCAGGDVVAIYHSAKADGAEARRF 90 >3SWN-B nrPDB Length = 77 Score = 26.9 bits (58), Expect = 9.4, Method: Compositional matrix adjust. Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 2/50 (4%) Query: 66 FSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVL 115 SSG D+KGI N T ++V N NVY DAFI+ + VL Sbjct: 23 LSSGVDYKGILSCLDGYMNLALERTEEYV-NGKKTNVY-GDAFIRGNNVL 70 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4ZDC-A nrPDB 409 e-115 5ZAI-A nrPDB 236 7e-63 2DUB-A nrPDB 236 9e-63 2HW5-A nrPDB 232 2e-61 3MOY-A nrPDB 224 4e-59 5VE2-A nrPDB 212 1e-55 5WYB-B nrPDB 197 5e-51 4FZW-A nrPDB 196 6e-51 5YLO-A nrPDB 195 2e-50 4JFC-A nrPDB 185 2e-47 4FZW-C nrPDB 181 2e-46 5JBW-A nrPDB 174 4e-44 Sequences not found previously or not previously below threshold: 3H81-A nrPDB 189 1e-48 5Z7R-A nrPDB 175 2e-44 2PPY-A nrPDB 147 5e-36 5ZRV-A nrPDB 134 3e-32 1NZY-B nrPDB 134 3e-32 4JCS-A nrPDB 133 9e-32 4JWV-A nrPDB 133 1e-31 6IUM-B nrPDB 132 2e-31 3HIN-A nrPDB 128 3e-30 2IEX-A nrPDB 127 7e-30 2VSU-C nrPDB 127 7e-30 3OME-A nrPDB 125 2e-29 3T88-A nrPDB 125 2e-29 3HE2-A nrPDB 124 4e-29 3T8B-A nrPDB 123 6e-29 4EML-A nrPDB 121 3e-28 3BPT-A nrPDB 121 4e-28 2UZF-A nrPDB 120 8e-28 5KJP-A nrPDB 118 2e-27 4IZC-A nrPDB 118 3e-27 6OJM-A nrPDB 117 5e-27 4JSB-A nrPDB 114 3e-26 2WTB-A nrPDB 114 3e-26 2D3T-A nrPDB 113 1e-25 3ZWA-A nrPDB 112 2e-25 4ZU2-A nrPDB 110 8e-25 3I47-A nrPDB 108 2e-24 3LAO-A nrPDB 108 3e-24 5MRE-88 nrPDB 102 2e-22 2A81-A nrPDB 101 4e-22 4HDT-A nrPDB 101 5e-22 1EF9-A nrPDB 99 2e-21 4Q1J-A nrPDB 93 2e-19 4J2U-A nrPDB 92 2e-19 4B3J-A nrPDB 89 2e-18 2NP9-A nrPDB 88 3e-18 3HP0-A nrPDB 85 2e-17 1XX4-A nrPDB 85 3e-17 4HC8-A nrPDB 81 5e-16 3JU1-A nrPDB 74 5e-14 3M6N-A nrPDB 67 1e-11 3VZ3-A nrPDB 33 0.12 4PZ2-A nrPDB 33 0.15 1UM9-A nrPDB 31 0.88 3GTD-A nrPDB 30 1.1 3GOL-A nrPDB 29 2.3 >4ZDC-A nrPDB Length = 300 Score = 409 bits (1050), Expect = e-115, Method: Composition-based stats. Identities = 279/280 (99%), Positives = 280/280 (100%) Query: 1 MSQEIRQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQ 60 MSQEIRQNEKISYRIEGPFFIIHL+NPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQ Sbjct: 21 MSQEIRQNEKISYRIEGPFFIIHLINPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQ 80 Query: 61 SSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLN 120 SSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLN Sbjct: 81 SSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLN 140 Query: 121 GPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMF 180 GPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMF Sbjct: 141 GPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMF 200 Query: 181 NKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNH 240 NKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNH Sbjct: 201 NKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNH 260 Query: 241 IDAFNKANSVEVNESLKYWVDGEPLKRFRQLGSKQRKHRL 280 IDAFNKANSVEVNESLKYWVDGEPLKRFRQLGSKQRKHRL Sbjct: 261 IDAFNKANSVEVNESLKYWVDGEPLKRFRQLGSKQRKHRL 300 >5ZAI-A nrPDB Length = 259 Score = 236 bits (602), Expect = 7e-63, Method: Composition-based stats. Identities = 56/212 (26%), Positives = 85/212 (40%), Gaps = 14/212 (6%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSS 68 E I + EG F I L PD LNAL + L + A+ + ++ II G+ F + Sbjct: 4 ETIETKKEGNLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKGKAFCA 63 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 GAD + P+E K F + + D SK I +NG A+G Sbjct: 64 GADITQFNQL-------TPAEAWK----FSKKGREIMDKIEALSKPTIAMINGYALGGGL 112 Query: 129 ALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDI 188 L CDI + + L P NLG+ G T L G E +M Sbjct: 113 ELALACDIRIAAEE-AQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKD 171 Query: 189 MCENGFISKNFNMPSSNAEAFNAKVLEELREK 220 + G +++ +P +N E K+ E++ +K Sbjct: 172 AEKYGLVNRV--VPLANLEQETRKLAEKIAKK 201 >2DUB-A nrPDB Length = 261 Score = 236 bits (601), Expect = 9e-63, Method: Composition-based stats. Identities = 56/255 (21%), Positives = 96/255 (37%), Gaps = 31/255 (12%) Query: 9 EKISYRIEG---PFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRF 65 + I +G +I L P LNAL L + LE + + V ++ + Sbjct: 5 QYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKA 64 Query: 66 FSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIG 125 F++GAD K + D + K++S++ D + K +I +NG A+G Sbjct: 65 FAAGADIKEMQNRTFQDCY-----SGKFLSHW--------DHITRIKKPVIAAVNGYALG 111 Query: 126 LSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFK 185 L +CDI+Y+ +K P LG I G T L G + E ++ Sbjct: 112 GGCELAMMCDIIYA-GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRIS 170 Query: 186 YDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFN 245 + G +SK F + + EA EK+ K++ + ++ N Sbjct: 171 AQDAKQAGLVSKIFPVETLVEEAIQC------AEKIANNS--------KIIVAMAKESVN 216 Query: 246 KANSVEVNESLKYWV 260 A + + E K Sbjct: 217 AAFEMTLTEGNKLEK 231 >2HW5-A nrPDB Length = 286 Score = 232 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 54/255 (21%), Positives = 94/255 (36%), Gaps = 31/255 (12%) Query: 9 EKISYRIEGP---FFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRF 65 E I G +I L P LNAL L + L++ + + V ++ + Sbjct: 30 EYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKIFEEDPAVGAIVLTGGDKA 89 Query: 66 FSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIG 125 F++GAD K + D +SK++ ++ D + K +I +NG A G Sbjct: 90 FAAGADIKEMQNLSFQDCY-----SSKFLKHW--------DHLTQVKKPVIAAVNGYAFG 136 Query: 126 LSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFK 185 L +CDI+Y+ +K P +G I G T L G + E ++ Sbjct: 137 GGCELAMMCDIIYA-GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRIS 195 Query: 186 YDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFN 245 + G +SK + + EA EK+ K++ + ++ N Sbjct: 196 AQDAKQAGLVSKICPVETLVEEAIQC------AEKIASNS--------KIVVAMAKESVN 241 Query: 246 KANSVEVNESLKYWV 260 A + + E K Sbjct: 242 AAFEMTLTEGSKLEK 256 >3MOY-A nrPDB Length = 263 Score = 224 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 47/251 (18%), Positives = 91/251 (36%), Gaps = 28/251 (11%) Query: 12 SYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGAD 71 + R +I L PD LNAL + + D + ++ ++ S R F++GAD Sbjct: 13 TSRPVAGVGLIRLDRPDALNALNQTLEAEVLDAARDFDADLEIGAIVVTGSERAFAAGAD 72 Query: 72 FKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALV 131 + + + +S + D+ + K ++ + G A+G L Sbjct: 73 IAEMVT-----LTPHQARERNLLSGW--------DSLTQVRKPIVAAVAGYALGGGCELA 119 Query: 132 ALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCE 191 LCD+V + D P LG++ G T L G + + + + Sbjct: 120 MLCDLVIA-ADTARFGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAER 178 Query: 192 NGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVE 251 G +S+ EA + +++ + P+ +K DA N+A Sbjct: 179 VGLVSRIVPAADLLDEALA------VAQRIARMSRPAGRAVK--------DAINEAFERP 224 Query: 252 VNESLKYWVDG 262 ++ ++Y D Sbjct: 225 LSAGMRYERDA 235 >5VE2-A nrPDB Length = 275 Score = 212 bits (539), Expect = 1e-55, Method: Composition-based stats. Identities = 48/244 (19%), Positives = 101/244 (41%), Gaps = 21/244 (8%) Query: 8 NEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFS 67 ++ ++ + + + P+ NAL E Y L + LE ++ + + ++ ++G F+ Sbjct: 24 SKSLNVSLNNRVLSLTINRPELKNALNRELYAALADELERSNHDDQIRAVLLTANGDTFT 83 Query: 68 SGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLS 127 +G D D N + V F+ A + ++ +NGPAIG+ Sbjct: 84 AGNDLD-------DFINPVEESGTPSVIRFL-------KAISECETPIVVAVNGPAIGVG 129 Query: 128 AALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 187 ++ CD+VY+ + PF ++GL+ E +++ LPL G + ++ + Sbjct: 130 LTMLLHCDMVYA-SKSARFRAPFTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAR 188 Query: 188 IMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKA 247 G +++ F AE+ ++ E+V L S K+L++ + + Sbjct: 189 EALSAGLVTRVFEDDVLVAESL------KIAEQVASLAPNSVKQSKRLIRGVNKEEVQAQ 242 Query: 248 NSVE 251 E Sbjct: 243 MKRE 246 >5WYB-B nrPDB Length = 280 Score = 197 bits (500), Expect = 5e-51, Method: Composition-based stats. Identities = 51/240 (21%), Positives = 91/240 (37%), Gaps = 26/240 (10%) Query: 10 KISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFFSS 68 K++ G +I + +P N + + I L +L+E +R+ D+Y ++ G +FFS+ Sbjct: 18 KLTVEKHGHTALITINHPPA-NTWDRDSLIGLRQLIEHLNRDDDIYALVVTGQGPKFFSA 76 Query: 69 GADFKGIA---KAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIG 125 GAD A KA+ + + E + + +F V I +NG A+G Sbjct: 77 GADLNMFADGDKARAREMARRFGEAFEALRDF--------------RGVSIAAINGYAMG 122 Query: 126 LSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFK 185 CDI + + + P A +GL+ G T +LP G ++ N+ Sbjct: 123 GGLECALACDIRIA-ERQAQMALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILCNERVD 181 Query: 186 YDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFN 245 + G + + L KV + +K L++ A N Sbjct: 182 AETALRIGLVEQV------VDSGEARGAALLLAAKVARQSPVAIRTIKPLIQGARERAPN 235 >4FZW-A nrPDB Length = 258 Score = 196 bits (499), Expect = 6e-51, Method: Composition-based stats. Identities = 52/274 (18%), Positives = 98/274 (35%), Gaps = 33/274 (12%) Query: 5 IRQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGR 64 +R ++ + ++ L P NAL + L LE A + + +I + R Sbjct: 1 MRSMSELIVSRQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNAR 60 Query: 65 FFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAI 124 FF++GAD +A+ D ++T + +K LI +NG A+ Sbjct: 61 FFAAGADLNEMAE---KDLAATLNDTRPQL----------WARLQAFNKPLIAAVNGYAL 107 Query: 125 GLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPF 184 G L LCD+V + + + P LG++ G T L G + + ++ + Sbjct: 108 GAGCELALLCDVVVAGENARF-GLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESI 166 Query: 185 KYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAF 244 + G +S F + A L K+ + K+ L+ Sbjct: 167 TAQQAQQAGLVSDVFPSDLTLEYALQ------LASKMARHSPLALQAAKQALR------- 213 Query: 245 NKANSVEVNESLKYWVDGEPLKRFRQLGSKQRKH 278 ++ V + L + F L + + +H Sbjct: 214 -QSQEVALQAGLAQER-----QLFTLLAATEDRH 241 >5YLO-A nrPDB Length = 271 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 44/267 (16%), Positives = 90/267 (33%), Gaps = 19/267 (7%) Query: 11 ISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGA 70 + R+E + L P NAL+ L L+ +R+ V ++ SGR F +GA Sbjct: 7 LQTRVEAGIAWLVLNRPQQRNALDIPTLEALHVRLDACERDPAVRAVVLGGSGRSFCAGA 66 Query: 71 DFKGIAKAQGDDTNKYPSETSKW--VSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 D A A+ + E+ W ++ + ++ D K + +NG A+G Sbjct: 67 DLAEWAAAEA----RGELESYGWTEAAHALMGRLHALD------KPTVAAVNGSAVGAGM 116 Query: 129 ALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDI 188 L CD + + + + + G + LP G+ L ++ + + Sbjct: 117 DLALCCDFRIAAASARF-KAGYTGMAYCPDAGASWHLPRLLGSEAAKRLLFLDEAWSAER 175 Query: 189 MCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKAN 248 G + + + ++ + K+LL+ + + Sbjct: 176 ALGAGLVGEVVADEHLVE------AVGAFAARLASGPTFAFAQTKRLLRDGAGRSLAEQL 229 Query: 249 SVEVNESLKYWVDGEPLKRFRQLGSKQ 275 E L + + R + K+ Sbjct: 230 RAEQAAGLLCGRSEDAAEALRAVAEKR 256 >3H81-A nrPDB Length = 278 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 49/252 (19%), Positives = 81/252 (32%), Gaps = 28/252 (11%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSS 68 E I + II L P LNAL + + D + D+ II S + F++ Sbjct: 25 ETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAA 84 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 GAD K +A D F A I + G A+G Sbjct: 85 GADIKEMADLTFADA-------------FTADFFATWGKLAAVRTPTIAAVAGYALGGGC 131 Query: 129 ALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDI 188 L +CD++ + D P LG++ G + L G + ++ + Sbjct: 132 ELAMMCDVLIA-ADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAE 190 Query: 189 MCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKAN 248 +G +S+ EA + + + K +A N+A Sbjct: 191 AERSGLVSRVVPADDLLTEA------RATATTISQMSASAARMAK--------EAVNRAF 236 Query: 249 SVEVNESLKYWV 260 ++E L Y Sbjct: 237 ESSLSEGLLYER 248 >4JFC-A nrPDB Length = 281 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 53/251 (21%), Positives = 108/251 (43%), Gaps = 23/251 (9%) Query: 11 ISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGA 70 I EG I+ L NP+ NAL E Y E L A+ N ++ +I G F +G Sbjct: 27 IKSTSEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVFCAGG 86 Query: 71 DFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAAL 130 + + + +A + + +++ + + N++ D+ + K +I + G A G +L Sbjct: 87 NLQRL-QANRREAPEVQAQSIEGLHNWI-------DSIRTYPKPVIAAVEGAAAGAGFSL 138 Query: 131 VALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMC 190 CD V + ++ V+++ ++ +GL +GG + SL E LM + + Sbjct: 139 ALACDFVVAASNAVFVM-SYSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLH 197 Query: 191 ENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSV 250 + G ++K + + +EA + ++ + +K+L N+A+S Sbjct: 198 DLGLVNKVASAGDALSEAL------RMAGQLNARAPNALASIKEL--------INEASSN 243 Query: 251 EVNESLKYWVD 261 +++ L D Sbjct: 244 TLSQQLACERD 254 >4FZW-C nrPDB Length = 274 Score = 181 bits (459), Expect = 2e-46, Method: Composition-based stats. Identities = 59/258 (22%), Positives = 96/258 (37%), Gaps = 24/258 (9%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSS 68 E I +E + L P+ LN+ E + L E L+ +R+ + ++ +GR F + Sbjct: 15 EFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCA 74 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVT-DAFIKHSKVLICCLNGPAIGLS 127 G D D N P+ + + V R K K +IC +NG A G Sbjct: 75 GQDLN--------DRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAG 126 Query: 128 AALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 187 A L DIV + +++ F+ LGLI + G T LP G + + Sbjct: 127 ATLALGGDIVIAARSAKFVMA-FSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAE 185 Query: 188 IMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKA 247 E G I + + + A ++L + LG+ K A N A Sbjct: 186 QAHEWGMIWQVVDDETL------ADTAQQLARHLAT-QPTFGLGLIK-------QAINSA 231 Query: 248 NSVEVNESLKYWVDGEPL 265 + ++ L D + L Sbjct: 232 ETNTLDTQLDLERDYQRL 249 >5Z7R-A nrPDB Length = 267 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 44/250 (17%), Positives = 88/250 (35%), Gaps = 27/250 (10%) Query: 14 RIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFFSSGADF 72 EG ++ + P LNAL + + ++ + + +V I+ +G + F +GAD Sbjct: 9 EKEGKVAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFVAGADI 68 Query: 73 KGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVA 132 + + N + N V R K +I +NG A+G + Sbjct: 69 SEM-----KEMNTIEGRKFGILGNKVFRR------LELLEKPVIAAVNGFALGGGCEIAM 117 Query: 133 LCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCEN 192 CDI + ++ + P LG+ G T L G + + + K D Sbjct: 118 SCDIRIASSNARF-GQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRI 176 Query: 193 GFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEV 252 G ++K + +E+ K+ + K+ A N+ ++ Sbjct: 177 GLVNKV------VEPSELMNTAKEIANKIVSNAPVAVKLSKQ--------AINRGMQCDI 222 Query: 253 NESLKYWVDG 262 + +L + + Sbjct: 223 DTALAFESEA 232 >5JBW-A nrPDB Length = 260 Score = 174 bits (440), Expect = 4e-44, Method: Composition-based stats. Identities = 53/260 (20%), Positives = 86/260 (33%), Gaps = 19/260 (7%) Query: 17 GPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFFSSGADFKGI 75 GP I + NA+ LGEL+ +RDV +I +G + F +GAD K Sbjct: 12 GPIEIWTIDGESRRNAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGADLKER 71 Query: 76 AKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCD 135 A D+ + + A K V I +NG A+G L CD Sbjct: 72 ATMAEDEVRAFLDGLRRTFR-----------AIEKSDCVFIAAINGAALGGGTELALACD 120 Query: 136 IVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFI 195 + + L LG+I GG T L G + ++ + G Sbjct: 121 LRVA-APAAELGLTEVKLGIIPGGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLA 179 Query: 196 SKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVNES 255 ++ E V L E V + K + + A ++E+ + Sbjct: 180 NRLAP------EGHLLAVAYGLAESVVENAPIAVATAKHAIDEGTGLELDDALALELRKY 233 Query: 256 LKYWVDGEPLKRFRQLGSKQ 275 + + L+ R K+ Sbjct: 234 EEILKTEDRLEGLRAFAEKR 253 >2PPY-A nrPDB Length = 265 Score = 147 bits (371), Expect = 5e-36, Method: Composition-based stats. Identities = 48/270 (17%), Positives = 98/270 (36%), Gaps = 28/270 (10%) Query: 7 QNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSS-GRF 65 + + ++ E IHL + + N+ + E Y ++ + D+ I+ S +F Sbjct: 7 KKQYLTVFKEDGIAEIHL-HINKSNSYDLEFYKEFNAAIDDIRFDPDIKVVIVMSDVPKF 65 Query: 66 FSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIG 125 FS+GAD + A + F D + +V I CL G +G Sbjct: 66 FSAGADINFLRSADPRFKTQ-----------FCLFCNETLDKIARSPQVYIACLEGHTVG 114 Query: 126 LSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFK 185 + CD+ + ++ + P +LG++ G T L G + + + + Sbjct: 115 GGLEMALACDLRFMGDEAGKIGLPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETIT 174 Query: 186 YDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFN 245 E G +++ F +A + E K+ + +K A Sbjct: 175 PQEALEIGLVNRVFP------QAETRERTREYARKLANSATYAVSNIKL--------AIM 220 Query: 246 KANSVEVNESLKYWVDGEPLKRFRQLGSKQ 275 + +N +++Y + + L FR +K+ Sbjct: 221 NGKEMPLNVAIRYEGELQNL-LFRSEDAKE 249 >5ZRV-A nrPDB Length = 763 Score = 134 bits (338), Expect = 3e-32, Method: Composition-based stats. Identities = 36/190 (18%), Positives = 74/190 (38%), Gaps = 13/190 (6%) Query: 11 ISYRIEGPFFIIHLMNPDNL-NALEGEDYIYLGELLELADRNRDVY-FTIIQSSGRFFSS 68 I+Y ++G ++ + +P++ N L E + E++ + + +I S F + Sbjct: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 GAD +A + T + V+ + + K +K ++ +NG +G Sbjct: 101 GADINMLAACK----------TLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGL 150 Query: 129 ALVALCDIVYSIND-KVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 187 + C + D K L P LG + G T LP G + ++ + + D Sbjct: 151 EVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRAD 210 Query: 188 IMCENGFISK 197 + G + + Sbjct: 211 RAKKMGLVDQ 220 >1NZY-B nrPDB Length = 269 Score = 134 bits (338), Expect = 3e-32, Method: Composition-based stats. Identities = 34/244 (13%), Positives = 85/244 (34%), Gaps = 13/244 (5%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSS 68 E I +R+E I + P + NAL + + + L A+ + V +I + F + Sbjct: 3 EAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCA 62 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 G + I +K + + I+ + ++ +NG A G Sbjct: 63 GFYLREIP------LDKGVAGVRDHFRIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGL 116 Query: 129 ALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDI 188 + D+ + ++ + +G+ + T+ SL G E ++ ++ + Sbjct: 117 GISLASDMAICADSAKFVCA-WHTIGIGNDTATSYSLARIVGMRRAMELMLTDRTLYPEE 175 Query: 189 MCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKAN 248 + G +S+ + +V ++ ++ + K+ + + + Sbjct: 176 AKDWGLVSRVYPKD------EFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECT 229 Query: 249 SVEV 252 E+ Sbjct: 230 EFEI 233 >4JCS-A nrPDB Length = 286 Score = 133 bits (334), Expect = 9e-32, Method: Composition-based stats. Identities = 45/267 (16%), Positives = 85/267 (31%), Gaps = 15/267 (5%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSS 68 + + + + I + N + E L +LE + D+ ++ S F + Sbjct: 24 DTLDFEVVNNVGWIRMNRAAKHNPFDAELRADLMTVLERVRDDADIRVLVLTSHPGSFCA 83 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 G + + + S + W ++ D + +I ++GPA G Sbjct: 84 GGNLHVL-------RDNLDSGPAYWQQRIKTGLRFIHDML-NLGRPVIAAVDGPAFGAGF 135 Query: 129 ALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDI 188 AL DIV + + + + LGL+ + G LP G E + + + Sbjct: 136 ALSLTADIVLASPRARFSMA-YLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEE 194 Query: 189 MCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKAN 248 G + + + A E+ E + + K L + Sbjct: 195 AHRLGLVMEVHESEALEQRA------REIAESLVQAAPTALALTKAALNVSLDSDEQTMF 248 Query: 249 SVEVNESLKYWVDGEPLKRFRQLGSKQ 275 S+E + EP L SKQ Sbjct: 249 SLEAASQAAAFSTKEPRAAIEALLSKQ 275 >4JWV-A nrPDB Length = 278 Score = 133 bits (334), Expect = 1e-31, Method: Composition-based stats. Identities = 39/208 (18%), Positives = 75/208 (36%), Gaps = 17/208 (8%) Query: 11 ISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFFSSG 69 I +RIEG + L P LNA+ E L + + N D++ ++ + G + F G Sbjct: 26 IDFRIEGHVAHVRLNRPQGLNAITQEMDDLLLDAWTEVNANSDIWAVVLSAEGEKAFCIG 85 Query: 70 ADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAA 129 AD G A+ + + + K ++ + G +G Sbjct: 86 ADVSGGAERKTRMALG-------------GGLTGIGGPLVTCKKPMVAAVQGFCVGGGFE 132 Query: 130 LVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIM 189 L DI+ + D P +G+I E G + + + ++ + K D Sbjct: 133 LAMCADIIVA-ADTAQFGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIKADEA 191 Query: 190 CENGFISKNFNMPSSNAEAFNAKVLEEL 217 G +++ +P + E + +L Sbjct: 192 RHYGLVNEV--VPFAELEEAALRWASKL 217 >6IUM-B nrPDB Length = 701 Score = 132 bits (331), Expect = 2e-31, Method: Composition-based stats. Identities = 49/269 (18%), Positives = 87/269 (32%), Gaps = 36/269 (13%) Query: 12 SYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGAD 71 Y+++ +I L NP +N L + + E + A + V +I +G+ FS GAD Sbjct: 4 QYQVQDGVAVITLDNPP-VNGLGHSTRLGIVEGMTRALDDAAVKAIVITGAGKAFSGGAD 62 Query: 72 FKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALV 131 + + S V SK ++ ++ A+G L Sbjct: 63 IREFNTPKAMQEPTLHS---------------VIRVLEGSSKPVVAAVHSVAMGGGLELA 107 Query: 132 ALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCE 191 C+ + + + P LGL+ G T LP G ++ P + Sbjct: 108 LGCNYRVA-SKGAQIALPEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSEKFAG 166 Query: 192 NGFISKNF---NMPSSNAEAFNA-------------KVLEELREKVKGLYLPSCLGMKKL 235 + +P++ A N KV E E G + M K Sbjct: 167 TKLFDEIVDGDVLPAAVKFAQNVGAATGPHPKVRDLKVRHENPEGYLGFARNTVAAMAKN 226 Query: 236 LKS--NHIDAFNKANSVEVNESLKYWVDG 262 + ++A + + LK +G Sbjct: 227 FPAPLKCLEAVAGSL-KPFEQGLKQEREG 254 >3HIN-A nrPDB Length = 275 Score = 128 bits (321), Expect = 3e-30, Method: Composition-based stats. Identities = 45/222 (20%), Positives = 68/222 (30%), Gaps = 20/222 (9%) Query: 5 IRQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGR 64 I + GP I L P NAL L + L D + +I G Sbjct: 12 IADPSTLVVDTVGPVLTIGLNRPKKRNALNDGLMAALKDCLT--DIPDQIRAVVIHGIGD 69 Query: 65 FFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAI 124 FS+G D + + D + + W F D +I L G I Sbjct: 70 HFSAGLDLSEL---RERDATEGLVHSQTWHRVF--------DKIQYCRVPVIAALKGAVI 118 Query: 125 GLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPF 184 G L I + Y P + G+ GG +V LP G + ++ + + Sbjct: 119 GGGLELACAAHIRVAEAS-AYYALPEGSRGIFVGGGGSVRLPRLIGVARMADMMLTGRVY 177 Query: 185 KYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYL 226 +GF S+ +A EL +V Sbjct: 178 SAAEGVVHGFSQYLIENGSAYDKAL------ELGNRVAQNAP 213 >2IEX-A nrPDB Length = 272 Score = 127 bits (318), Expect = 7e-30, Method: Composition-based stats. Identities = 46/269 (17%), Positives = 90/269 (33%), Gaps = 19/269 (7%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFFS 67 E I Y I + P+ NA + + + A + ++ I+ +G + F Sbjct: 12 EDIIYETYNGIAKITINRPEVHNAFRPKTVNEMIDAFTKARDDSNIGVIILTGAGGKAFC 71 Query: 68 SGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLS 127 SG D K +G E + + + K +I + G AIG Sbjct: 72 SGGD----QKVRGHGGYVGEDEIPR------LNVLDLQRLIRVIPKPVIAMVAGYAIGGG 121 Query: 128 AALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 187 L +CD+ + ++ ++ +G G L G E + + Sbjct: 122 HVLHVVCDLTIAADNAIF-GQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYTAQ 180 Query: 188 IMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKA 247 E G ++K +P E K +E+ EK + +K ++ D Sbjct: 181 EALEMGLVNKV--VPLEQLEEETVKWAQEILEK----SPTAIRFLKAAFNADS-DGLAGI 233 Query: 248 NSVEVNESLKYWVDGEPLKRFRQLGSKQR 276 + + +L ++ E + R K++ Sbjct: 234 QQLAGDATLLFYTTEEAKEGMRAFKEKRK 262 >2VSU-C nrPDB Length = 275 Score = 127 bits (318), Expect = 7e-30, Method: Composition-based stats. Identities = 36/226 (15%), Positives = 82/226 (36%), Gaps = 9/226 (3%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSS 68 + + IE + L P+ NA+ + ++LE +++ ++ +G +++ Sbjct: 9 KTVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAWTA 68 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 G D K + + P + + + + ++K I +NG G Sbjct: 69 GMDLKEY----FREVDAGPEILQEKIRR--EASQWQWKLLRMYAKPTIAMVNGWCFGGGF 122 Query: 129 ALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDI 188 A + CD+ D+ N G+ + ++ G + +M K F Sbjct: 123 APLVACDLAI-CADEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQK 181 Query: 189 MCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKK 234 E G ++++ +P + ++ L EK + + G K+ Sbjct: 182 AAEMGLVNES--VPLAQLREVTIELARNLLEKNPVVLRAAKHGFKR 225 >3OME-A nrPDB Length = 282 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 43/229 (18%), Positives = 83/229 (36%), Gaps = 19/229 (8%) Query: 10 KISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSG 69 I Y + I L P+ NA E L A + +V I++++G+ FS+G Sbjct: 24 YIDYGVADSIATITLNRPEAANAQNPELLDELDAAWTRAAEDNEVKVIILRANGKHFSAG 83 Query: 70 ADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAA 129 D +G + + ++ + + R + T + K I + G I Sbjct: 84 HDLRGGGEVPEKISLEFI------IQHEARRYLDYTLRWRNVPKPSIAAVQGRCISGGLL 137 Query: 130 LVALCDIVYSINDKVYLLYPFANLGL--ITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 187 L CD++ + +D P A +G+ + G T L G E L + + Sbjct: 138 LCWPCDLILA-SDDALFSDPVALMGIGGVEYHGHTWEL----GPRKAKEILFTGRALTAE 192 Query: 188 IMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLL 236 G +++ +A+ EL E++ + + K+ + Sbjct: 193 EAERTGMVNRVVARDELDAQT------RELAEQIATMPPFALRQAKRAV 235 >3T88-A nrPDB Length = 289 Score = 125 bits (313), Expect = 2e-29, Method: Composition-based stats. Identities = 43/260 (16%), Positives = 88/260 (33%), Gaps = 25/260 (9%) Query: 9 EKISYRIEG-PFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFF 66 E I Y I + P NA + + L A + ++ I+ +G + F Sbjct: 27 EDIRYEKSTDGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAF 86 Query: 67 SSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDA-FIKHSKVLICCLNGPAIG 125 SG D K + K S NV K ++ + G +IG Sbjct: 87 CSGGDQKV----------RGDYGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIG 136 Query: 126 LSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFK 185 L +CD+ + ++ ++ +G G + G E + + Sbjct: 137 GGHVLHMMCDLTIAADNAIF-GQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYD 195 Query: 186 YDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFN 245 + G + N +P ++ E + E+ + S + ++ L + + D Sbjct: 196 AKQALDMGLV--NTVVPLADLEKETVRWCREMLQ-------NSPMALRCLKAALNADCDG 246 Query: 246 KANSVEV--NESLKYWVDGE 263 +A E+ N ++ +++ E Sbjct: 247 QAGLQELAGNATMLFYMTEE 266 >3HE2-A nrPDB Length = 264 Score = 124 bits (311), Expect = 4e-29, Method: Composition-based stats. Identities = 42/229 (18%), Positives = 81/229 (35%), Gaps = 30/229 (13%) Query: 19 FFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKA 78 I L P+ NAL + L + + A + ++ G F +GAD G A Sbjct: 31 VLTIELQRPERRNALNSQLVEELTQAIRKAG-DGSARAIVLTGQGTAFCAGADLSGDA-- 87 Query: 79 QGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVY 138 + +++ R + + A ++ +NGPAIG L CD+ Sbjct: 88 --------------FAADYPDRLIELHKAMDASPMPVVGAINGPAIGAGLQLAMQCDLRV 133 Query: 139 SINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKN 198 + + +P + GL + + L G L+ + +I G ++ Sbjct: 134 -VAPDAFFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEIALHTGMANRI 192 Query: 199 FNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKA 247 ++A+A+ ++ L + K++L N A +A Sbjct: 193 GT--LADAQAW--------AAEIARLAPLAIQHAKRVL--NDDGAIEEA 229 >3T8B-A nrPDB Length = 334 Score = 123 bits (309), Expect = 6e-29, Method: Composition-based stats. Identities = 38/214 (17%), Positives = 74/214 (34%), Gaps = 9/214 (4%) Query: 14 RIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGR-------FF 66 ++ + P+ NA L +L+ A + DV ++ +G F Sbjct: 62 HVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAF 121 Query: 67 SSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGL 126 SG D + ++ + ++T + V KV+IC +NG A G Sbjct: 122 CSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGG 181 Query: 127 SAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKY 186 +L +CD+ + + A++G G + L + G E + + Sbjct: 182 GHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTA 241 Query: 187 DIMCENGFISKNFNMPSSNAEAFNAKVLEELREK 220 + M + G + N + E + E+ K Sbjct: 242 EQMHQMGAV--NAVAEHAELETVGLQWAAEINAK 273 >4EML-A nrPDB Length = 275 Score = 121 bits (304), Expect = 3e-28, Method: Composition-based stats. Identities = 39/264 (14%), Positives = 79/264 (29%), Gaps = 24/264 (9%) Query: 6 RQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGR- 64 + + I Y G I + P NA + L + A + + ++ +G Sbjct: 7 KHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPH 66 Query: 65 -----FFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCL 119 F SG D + D P + + KV+I + Sbjct: 67 SDGKYAFCSGGDQSVRGEGGYIDDQGTP----------RLNVLDLQRLIRSMPKVVIALV 116 Query: 120 NGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLM 179 G AIG L +CD+ + ++ ++ +G G + L G E Sbjct: 117 AGYAIGGGHVLHLVCDLTIAADNAIF-GQTGPKVGSFDGGFGSSYLARIVGQKKAREIWY 175 Query: 180 FNKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSN 239 + + G ++ + E +++ + +K ++ Sbjct: 176 LCRQYSAQEAERMGMVNTVVPVDRLEEEGIQW------AKEILSKSPLAIRCLKAAFNAD 229 Query: 240 HIDAFNKANSVEVNESLKYWVDGE 263 D + N +L Y++ E Sbjct: 230 -CDGQAGLQELAGNATLLYYMTEE 252 >3BPT-A nrPDB Length = 363 Score = 121 bits (302), Expect = 4e-28, Method: Composition-based stats. Identities = 43/248 (17%), Positives = 83/248 (33%), Gaps = 17/248 (6%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSS-GRFFS 67 E++ +G +I L P LNAL + L+ +++ + + II+ + G+ F Sbjct: 6 EEVLLGKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 65 Query: 68 SGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLS 127 +G D + I++A+ P F + +A K + ++G +G Sbjct: 66 AGGDIRVISEAEKAKQKIAPV--------FFREEYMLNNAVGSCQKPYVALIHGITMGGG 117 Query: 128 AALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 187 L + +K P +GL + G LP G Y + K Sbjct: 118 VGLSVHGQFRVAT-EKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGR 175 Query: 188 IMCENGFISKNFNMP-SSNAEAFNAKVLEELREKVKGLYLPSCLGM-----KKLLKSNHI 241 + G + + + E + +E + + K + H+ Sbjct: 176 DVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHM 235 Query: 242 DAFNKANS 249 D N S Sbjct: 236 DKINSCFS 243 >2UZF-A nrPDB Length = 273 Score = 120 bits (300), Expect = 8e-28, Method: Composition-based stats. Identities = 36/219 (16%), Positives = 76/219 (34%), Gaps = 16/219 (7%) Query: 3 QEIRQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSS 62 + +R+ ++I Y + + P+ NA + + + A +++V ++ Sbjct: 7 ETLREYDEIKYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGE 66 Query: 63 GR-FFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIK-HSKVLICCLN 120 G F SG D K ++ P NV I+ K +I + Sbjct: 67 GDLAFCSGGDQKKRGHGGYVGEDQIP-----------RLNVLDLQRLIRIIPKPVIAMVK 115 Query: 121 GPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMF 180 G A+G L +CD+ + ++ ++ +G G + L G E Sbjct: 116 GYAVGGGNVLNVVCDLTIAADNAIF-GQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYL 174 Query: 181 NKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELRE 219 + + + G + N +P E + +E+ + Sbjct: 175 CRQYNAQEALDMGLV--NTVVPLEKVEDETVQWCKEIMK 211 >5KJP-A nrPDB Length = 265 Score = 118 bits (296), Expect = 2e-27, Method: Composition-based stats. Identities = 39/226 (17%), Positives = 74/226 (32%), Gaps = 23/226 (10%) Query: 11 ISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGA 70 + II + P NA+ L + ++ D + + I+ G F +G Sbjct: 17 VLVEQRDRILIITINRPKAKNAVNAAVSRGLADAMDQLDGDAGLSVAILTGGGGSFCAGM 76 Query: 71 DFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAAL 130 D K A+ + N V + +K LI + G A+ L Sbjct: 77 DLKAFARGE----------------NVVVEGRGLGFTERPPTKPLIAAVEGYALAGGTEL 120 Query: 131 VALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMC 190 D++ + D + P GL+ GG + LP + E + + Sbjct: 121 ALAADLIVAARDSAF-GIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAH 179 Query: 191 ENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLL 236 E G ++ ++ A L EK+ + + K+++ Sbjct: 180 ELGLVNVLAEPGTALDAAIA------LAEKITANGPLAVVATKRII 219 >4IZC-A nrPDB Length = 275 Score = 118 bits (295), Expect = 3e-27, Method: Composition-based stats. Identities = 37/234 (15%), Positives = 78/234 (33%), Gaps = 15/234 (6%) Query: 16 EGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGI 75 + ++ L PD NAL+ L A R + V ++ +G F +G D Sbjct: 18 DNGVCVVTLNRPDKRNALDVATIEELVTFFSTAHR-KGVRAVVLTGAGDHFCAGLDLVEH 76 Query: 76 AKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCD 135 KA ++ + R + +I L G +G AL + Sbjct: 77 WKA---------DRSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLALASAAH 127 Query: 136 IVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFI 195 + ++ Y P G+ T GG T+ + G + ++ + ++ + G Sbjct: 128 LRV-MDQSTYFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLA 186 Query: 196 SKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHID-AFNKAN 248 S + + +++ + C + + + +D A+ +A Sbjct: 187 QYITEGSSFDKAME---LADKIASNLPLTNFAICSAISHMQNMSGLDAAYAEAF 237 >6OJM-A nrPDB Length = 286 Score = 117 bits (293), Expect = 5e-27, Method: Composition-based stats. Identities = 40/235 (17%), Positives = 75/235 (31%), Gaps = 23/235 (9%) Query: 6 RQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGR- 64 ++ E I+Y+ I P+ NA + L + A + + ++ G Sbjct: 16 KEYEDITYKKCNGVARIAFNRPEIRNAFRPKTTSELYDAFYDAYEDPSIGVVLLSGEGPS 75 Query: 65 ------FFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICC 118 F SG D KA+G + + V KV+I Sbjct: 76 PKDGGWAFCSGGD----QKARGHQGYVGEDGRHR------LNILEVQRLIRFMPKVVIAV 125 Query: 119 LNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECL 178 + G A+G +L +CD+ + + A++ G + L G E Sbjct: 126 VPGWAVGGGHSLHVVCDLTLASKEHAIFKQTDADVTSFDGGYGSAYLAKMVGQKKAREIF 185 Query: 179 MFNKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMK 233 + + E G ++K +P + E E +++ S +K Sbjct: 186 FLGRNYSAQEAFEMGMVNKV--VPHAELE----DTAYEWAQEILAKSPTSIRMLK 234 >4JSB-A nrPDB Length = 296 Score = 114 bits (286), Expect = 3e-26, Method: Composition-based stats. Identities = 40/202 (19%), Positives = 64/202 (31%), Gaps = 9/202 (4%) Query: 11 ISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGA 70 ++ I+G I L P NA+ G + L + + V +I G FSSG Sbjct: 38 LTLTIDGEVARITLSRPHRRNAMTGRMWTELARIGHTLPQ--AVRIVVITGEGPTFSSGI 95 Query: 71 DFKGIAKAQGD------DTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAI 124 D + D ++ + +A + V I + G AI Sbjct: 96 DLDMFQAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLWLRRADIVSIAAVRGHAI 155 Query: 125 GLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPF 184 G L CDI ++D L LGL+ + T L G N E + + Sbjct: 156 GAGFQLALSCDIRI-LSDTAQLCMKEPALGLVPDLTGTQPLVELVGVNRAIELCLTARTI 214 Query: 185 KYDIMCENGFISKNFNMPSSNA 206 + + +A Sbjct: 215 DAAEAAQLRLAERVVADAELDA 236 >2WTB-A nrPDB Length = 725 Score = 114 bits (286), Expect = 3e-26, Method: Composition-based stats. Identities = 45/203 (22%), Positives = 70/203 (34%), Gaps = 11/203 (5%) Query: 18 PFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAK 77 +I L+NP +N+L + L E A DV +I + FS G D G + Sbjct: 17 GVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGE 75 Query: 78 AQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIV 137 Q + + + +TD K + ++G A+G L C Sbjct: 76 MQKGNVKEPKAG--------YISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHAR 127 Query: 138 YSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISK 197 S L P LG+I G T LP G E ++ +KP K + G I Sbjct: 128 IS-APAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDA 186 Query: 198 NFNMPSSNAEAFNAKVLEELREK 220 P+ L+ + + Sbjct: 187 VVP-PAELVTTARRWALDIVGRR 208 >2D3T-A nrPDB Length = 715 Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 31/183 (16%), Positives = 62/183 (33%), Gaps = 9/183 (4%) Query: 28 DNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQGDDTNKYP 87 +++N L + ++ + V I+ S F GAD + + Sbjct: 27 ESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFVEN-------FK 79 Query: 88 SETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVYLL 147 ++ ++ + N +D F + + +NG A+G + D + D + Sbjct: 80 LPDAELIAGNLEANKIFSD-FEDLNVPTVAAINGIALGGGLEMCLAADFRV-MADSAKIG 137 Query: 148 YPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPSSNAE 207 P LG+ G TV LP G + E + K + + + + A Sbjct: 138 LPEVKLGIYPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADKLGAA 197 Query: 208 AFN 210 A + Sbjct: 198 ALD 200 >3ZWA-A nrPDB Length = 742 Score = 112 bits (279), Expect = 2e-25, Method: Composition-based stats. Identities = 39/204 (19%), Positives = 69/204 (33%), Gaps = 20/204 (9%) Query: 14 RIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFK 73 R+ +I L NP +NA+ + L+ A + V +I + F +GAD Sbjct: 26 RLPHSLAMIRLCNPP-VNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIH 84 Query: 74 GIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVAL 133 G + P + D ++ K ++ + G A+G L Sbjct: 85 GFSAF-------TPGLALGSL----------VDEIQRYQKPVLAAIQGVALGGGLELALG 127 Query: 134 CDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENG 193 C + K + P LG++ T LP G + + K D G Sbjct: 128 CHYRIANA-KARVGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLG 186 Query: 194 FISKNF-NMPSSNAEAFNAKVLEE 216 + + P A F K++++ Sbjct: 187 ILDAVVKSDPVEEAIKFAQKIIDK 210 >4ZU2-A nrPDB Length = 272 Score = 110 bits (274), Expect = 8e-25, Method: Composition-based stats. Identities = 39/228 (17%), Positives = 78/228 (34%), Gaps = 15/228 (6%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSS 68 E + I L P + NA+ L +L +R V +++ + F + Sbjct: 7 ETLLLEPIEGVLRITLNRPQSRNAMSLAMVGELRAVLAAVRDDRSVRALVLRGADGHFCA 66 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 G D K +A A+ Y + + S + + ++L+ + G +G Sbjct: 67 GGDIKDMAGARAAGAEAYRTLNRAFGS--------LLEEAQAAPQLLVALVEGAVLGGGF 118 Query: 129 ALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDI 188 L + D+ + D P +LG++ + + G + F Sbjct: 119 GLACVSDVAIAAAD-AQFGLPETSLGILP-AQIAPFVVRRIGLTQARRLALTAARFDGRE 176 Query: 189 MCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLL 236 G + ++A+A + LEE E+++ + K LL Sbjct: 177 ALRLGLVH----FCEADADALEQR-LEETLEQLRRCAPNANAATKALL 219 >3I47-A nrPDB Length = 268 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 37/236 (15%), Positives = 80/236 (33%), Gaps = 16/236 (6%) Query: 11 ISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGA 70 + Y I+ ++ + NA + + + L+ A + +V +++++G+ FS+GA Sbjct: 6 LLYEIQDKVGLLTMNRISKHNAFDNQLLTEMRIRLDSAINDTNVRVIVLKANGKHFSAGA 65 Query: 71 DFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAAL 130 D ++ + T + E S + N + + + K I + G A G A L Sbjct: 66 DLT-WMQSMANFTEEENLEDSLVLGN-------LMYSISQSPKPTIAMVQGAAFGGGAGL 117 Query: 131 VALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMC 190 A CDI + + + LGLI + + G M + F Sbjct: 118 AAACDIAIA-STSARFCFSEVKLGLIP-AVISPYVVRAIGERAAKMLFMSAEVFDATRAY 175 Query: 191 ENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNK 246 + + + ++ + K+L + ++ Sbjct: 176 SLNLVQHCVPDDTLLEFTL------KYASQISNNAPEAVKNSKQLAQYVANKKIDE 225 >3LAO-A nrPDB Length = 258 Score = 108 bits (269), Expect = 3e-24, Method: Composition-based stats. Identities = 44/266 (16%), Positives = 84/266 (31%), Gaps = 18/266 (6%) Query: 1 MSQEIRQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQ 60 MS+ +++ G F+I L NA + L + +R+ + ++ Sbjct: 4 MSEANSGPGRVTREQRGHLFLIGLDRAGKRNAFDSAMLADLALAMGEYERSEESRCAVLF 63 Query: 61 SSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLN 120 + G F++G D +A +YP V + + SK L+ + Sbjct: 64 AHGEHFTAGLDLMELAPKLAASGFRYPDGG---VDPWGVVQP-------RRSKPLVVAVQ 113 Query: 121 GPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMF 180 G L+ DI + + G+ GG+TV P G ++ Sbjct: 114 GTCWTAGIELMLNADIAVAARGTRFAHL-EVLRGIPPLGGSTVRFPRAAGWTDAMRYILT 172 Query: 181 NKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNH 240 F D +++ E E++ + + Sbjct: 173 GDEFDADEALRMRLLTEV------VEPGEELARALEYAERIARAAPLAVRAALQSAFQGR 226 Query: 241 IDAFNKANSVEVNESLKYWVDGEPLK 266 + + A S VNESL + E ++ Sbjct: 227 DEGDDAALSR-VNESLAALIGSEDVR 251 >5MRE-88 nrPDB Length = 457 Score = 102 bits (253), Expect = 2e-22, Method: Composition-based stats. Identities = 37/202 (18%), Positives = 75/202 (37%), Gaps = 17/202 (8%) Query: 21 IIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG--RFFSSGADFKGIAKA 78 +I L P LNAL E + + L ++ I++SS R F +G D +A Sbjct: 14 VITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDVATVAIF 73 Query: 79 QGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVY 138 NK +++ K+ ++ + N + K ++ ++G +G L Sbjct: 74 NF---NKEFAKSIKFFTDEYSLNFQ----IATYLKPIVTFMDGITMGGGVGLSIHTPFRI 126 Query: 139 SINDKVYLLYPFANLGLITEGGTTVSLPLKF-----GTNTTYECLMFNKPFKYDIMCENG 193 + + + + P ++G + G+T +LP + + + G Sbjct: 127 ATENTKWAM-PEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYMLG 185 Query: 194 FISKNFNMPSSNAEAFNAKVLE 215 S + S N +A ++ E Sbjct: 186 LASHY--VSSENLDALQKRLGE 205 >2A81-A nrPDB Length = 250 Score = 101 bits (251), Expect = 4e-22, Method: Composition-based stats. Identities = 32/215 (14%), Positives = 74/215 (34%), Gaps = 15/215 (6%) Query: 21 IIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTII-QSSGRFFSSGADFKGIAKAQ 79 +I L +P+ N + + L A+ + V ++ + R FS+G DF + + Sbjct: 12 VITLDHPNKHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAGGDFNEVKQLS 71 Query: 80 GDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYS 139 S+ + ++ R + + A + +K I ++G AIG+ + D Sbjct: 72 R----------SEDIEEWIDRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQRLM 121 Query: 140 INDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNF 199 + +++ P G I L G +T E + + + +++ Sbjct: 122 ASTANFVM-PELKHG-IGCSVGAAILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLVNQVV 179 Query: 200 NMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKK 234 + A + ++ + + K Sbjct: 180 ESSALLDAAITQ--AHVMASYPASAFINTKRAVNK 212 >4HDT-A nrPDB Length = 353 Score = 101 bits (250), Expect = 5e-22, Method: Composition-based stats. Identities = 34/201 (16%), Positives = 66/201 (32%), Gaps = 11/201 (5%) Query: 7 QNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RF 65 +NE + +EG ++ L P +N+L + E L + + V ++ +G R Sbjct: 7 KNEDVLVNVEGGVGLLTLNRPKAINSLTHGMVTTMAERLAAWENDDSVRAVLLTGAGERG 66 Query: 66 FSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIG 125 +G D I + D + F + ++ K + ++G +G Sbjct: 67 LCAGGDVVAIYHSAKADGAE--------ARRFWFDEYRLNAHIGRYPKPYVSIMDGIVMG 118 Query: 126 LSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFK 185 + A ++ + D + P +G I + G T L G + PF Sbjct: 119 GGVGVGAHGNVRV-VTDTTKMAMPEVGIGFIPDVGGTYLLSRAPGK-LGLHAALTGAPFS 176 Query: 186 YDIMCENGFISKNFNMPSSNA 206 GF + Sbjct: 177 GADAIVMGFADHYVPHDKIDE 197 >1EF9-A nrPDB Length = 261 Score = 99.1 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 38/224 (16%), Positives = 75/224 (33%), Gaps = 19/224 (8%) Query: 19 FFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQ--SSGRFFSSGADFKGIA 76 +I LNAL L + L +R ++ I++ S + FS+G D + Sbjct: 14 VAVIEFNYGRKLNALSKVFIDDLMQALSDLNR-PEIRCIILRAPSGSKVFSAGHDIHELP 72 Query: 77 KAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDI 136 D + + +T K K +I + G G + ++ D+ Sbjct: 73 SGGRDPLS------------YDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIMSSDL 120 Query: 137 VYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFIS 196 + + + + + P NLG+ +L G + E + P G ++ Sbjct: 121 IIAASTSTFSMTP-VNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALAVGILN 179 Query: 197 KNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNH 240 + E F ++ + EK L + ++L H Sbjct: 180 HVVEVEEL--EDFTLQMAHHISEK-APLAIAVIKEELRVLGEAH 220 >4Q1J-A nrPDB Length = 268 Score = 92.6 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 48/260 (18%), Positives = 85/260 (32%), Gaps = 21/260 (8%) Query: 12 SYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGAD 71 IE + + + + NA E L + E +N I+ +F+SG Sbjct: 27 LIEIESAIIQVKMQDRTHKNAFSQELTDDLIQAFEYIRQNPKYKAVILTGYDNYFASGG- 85 Query: 72 FKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALV 131 T + + ++ F N+Y + +I + G IG + Sbjct: 86 -----------TQEGLLRIQQGLTKFTDDNLYSLA--LDCEIPVIAAMQGHGIGGGFVMG 132 Query: 132 ALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCE 191 DIV + VY F G G T +P K G + E L+ ++ + + Sbjct: 133 LFADIVILSRESVY-TANFMKYGFTPGMGATFIVPKKLGFSLAQEILLNAGSYRGADLEK 191 Query: 192 NGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVE 251 G K A EL +++ S + +K L + D + E Sbjct: 192 RGVPFKVLP------RAEVLDYAVELAQELAEKPRNSLVTLKDHLVAPLRDQLPRVIEQE 245 Query: 252 VNESLKYWVDGEPLKRFRQL 271 + + K + E R + L Sbjct: 246 LMMAEKTFHHEEVKSRIKGL 265 >4J2U-A nrPDB Length = 365 Score = 92.2 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 30/180 (16%), Positives = 54/180 (30%), Gaps = 10/180 (5%) Query: 22 IHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFFSSGADFKGIAKAQG 80 I L P LNAL + L + +V +I + G R F +G D + Sbjct: 37 ITLSRPAALNALTCAMVQEIDAALRGWIGDPEVELVVIDAEGPRAFCAGGDIAELHG--- 93 Query: 81 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSI 140 + + + +F + D K ++ + G +G L + Sbjct: 94 ----RGVAGDHAFGQDFWRVEYRMNDRIAAFPKPIVSLMQGFTMGGGVGLGCHARHRI-V 148 Query: 141 NDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFN 200 + + P +GL+ + G T L G + GF + Sbjct: 149 GETSQISMPECAIGLVPDVGGTHLLARAPGR-IGVWLGLTGARMGPGDAIFAGFADRFVP 207 >4B3J-A nrPDB Length = 736 Score = 89.1 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 38/216 (17%), Positives = 76/216 (35%), Gaps = 13/216 (6%) Query: 8 NEKISYRIEG-PFFIIHLMNPD-NLNALEGEDYIYLGELLEL-ADRNRDVYFTIIQSSGR 64 + I + + + + +P + N + +G+ ++ + ++ S+ + Sbjct: 19 DNTIQWDKDADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKK 78 Query: 65 FFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAI 124 F +G D K + +A+ +D + V N V K ++ +NG A+ Sbjct: 79 TFFAGGDVKTMIQARPED--------AGDVFNTVETIKRQLRTLETLGKPVVAAINGAAL 130 Query: 125 GLSAALVALCDIVYSIN-DKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMF-NK 182 G + C + + L P LGL+ GG FG + ++ Sbjct: 131 GGGLEIALACHHRIAADVKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGT 190 Query: 183 PFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELR 218 FK E G + + A A + EEL+ Sbjct: 191 RFKPAKAKEIGLVDELVATVEELVPAAKAWIKEELK 226 >2NP9-A nrPDB Length = 440 Score = 88.3 bits (217), Expect = 3e-18, Method: Composition-based stats. Identities = 37/242 (15%), Positives = 82/242 (33%), Gaps = 25/242 (10%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSS------ 62 E + + + D LNA +G+ + ++LA + V +++ Sbjct: 167 EAVHLERRDGVARLTMCRDDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPR 226 Query: 63 ---GRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTD-----AFIKHSKV 114 R FS+G + K +++ + ++ V + D + K Sbjct: 227 YRGKRVFSAGINLKYLSQGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKP 286 Query: 115 LICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTT 174 + ++G AIG A L+ + D V + +D Y P A G+I + L G + Sbjct: 287 WVAAVDGFAIGGGAQLLLVFDRVLASSD-AYFSLPAAKEGIIPGA-ANLRLGRFAGPRVS 344 Query: 175 YECLMFNKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKK 234 + ++ + + + +A + + L + L ++ Sbjct: 345 RQVILEGRRIWAKEPEARLLVDEVVEPDELDAA---------IERSLTRLDGDAVLANRR 395 Query: 235 LL 236 +L Sbjct: 396 ML 397 >3HP0-A nrPDB Length = 267 Score = 85.3 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 53/187 (28%), Gaps = 12/187 (6%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSS 68 + I R + I P+ N + ++L + + V +++ F Sbjct: 7 QTIKVRFQASVCYITFHRPEANNTINDTLIEECLQVLNQCETS-TVTVVVLEGLPEVFCF 65 Query: 69 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 128 GADF+ I + + K S ++ V I + G Sbjct: 66 GADFQEIYQ-EMKRGRKQASSQEPLYDLWM--------KLQTGPYVTISHVRGKVNAGGL 116 Query: 129 ALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDI 188 V+ DI + + GL L + G + + KP Sbjct: 117 GFVSATDIAIA-DQTASFSLSELLFGLYPAC-VLPFLIRRIGRQKAHYMTLMTKPISVQE 174 Query: 189 MCENGFI 195 E G I Sbjct: 175 ASEWGLI 181 >1XX4-A nrPDB Length = 261 Score = 85.3 bits (209), Expect = 3e-17, Method: Composition-based stats. Identities = 40/247 (16%), Positives = 80/247 (32%), Gaps = 23/247 (9%) Query: 8 NEKISYRIEG--PFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRF 65 N+++ EG ++ NP +N+L E LE + ++ + I+ S Sbjct: 3 NKRVLVEKEGEAGIAVMKFKNPP-VNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPG 61 Query: 66 -FSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAI 124 FS+G D + + +E K V R + LI +NG + Sbjct: 62 IFSAGLDLMEMYGRN----PAHYAEYWKAVQELWLR-------LYLSNLTLISAINGASP 110 Query: 125 GLSAALVALCDIVYSINDKVY-LLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKP 183 + CD ++ Y + + LG++ + G L Sbjct: 111 AGGCLMALTCDYRIMADNSKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTL 170 Query: 184 FKYDIMCENGFISKNFNMPSSNAEAFNA-----KVLEELREKVKGLYLPSCLGMKKLLKS 238 F + G + + +++A + + + R+ K + + L+K Sbjct: 171 FPPAEALKVGLVDEVVPEDQVHSKARSVMAKWFTIPDHSRQLTKSMMRKA--TADNLIKQ 228 Query: 239 NHIDAFN 245 D N Sbjct: 229 READIQN 235 >4HC8-A nrPDB Length = 255 Score = 81.0 bits (198), Expect = 5e-16, Method: Composition-based stats. Identities = 41/237 (17%), Positives = 83/237 (35%), Gaps = 20/237 (8%) Query: 8 NEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFS 67 ++ +SY + +I + + +NAL L ++ ADR+ DV +I +GR FS Sbjct: 4 SDPVSYTRKDSIAVISMDD-GKVNALGPAMQQALNAAIDNADRD-DVGALVITGNGRVFS 61 Query: 68 SGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLS 127 G D K + + + + + + + K ++ G AI + Sbjct: 62 GGFDLKILTSGEVQP-----------AIDMLRGGFELAYRLLSYPKPVVMACTGHAIAMG 110 Query: 128 AALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 187 A L++ D + + +G+ + L+ + + K F + Sbjct: 111 AFLLSCGDHRVA-AHAYNIQANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFGE 169 Query: 188 IMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAF 244 GFI + + A EE + GL + K +++ + A Sbjct: 170 TALAAGFIDEIALPEVVVSRA------EEAAREFAGLNQHAHAATKLRSRADALTAI 220 >3JU1-A nrPDB Length = 407 Score = 74.5 bits (181), Expect = 5e-14, Method: Composition-based stats. Identities = 27/187 (14%), Positives = 61/187 (32%), Gaps = 7/187 (3%) Query: 9 EKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFFS 67 + ++ ++ L LNAL+ + + L L ++ + ++ SG + F Sbjct: 42 QTLATASGKLVGVVTLNVEKALNALDLDMVRAMTVQLNLWKKDPLIACVVLDGSGEKAFC 101 Query: 68 SGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLS 127 +G D + + A + ++ F + + K ++ +G +G Sbjct: 102 AGGDVRALYHASV----AAKGQVTEVAKVFFEEEYRLDYLLHTYGKPVLVWGDGIVMGGG 157 Query: 128 AALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 187 L+A + + + P +GL + G + L G + Sbjct: 158 LGLMAGASHKV-VTETSRIAMPEVTIGLYPDVGGSYFLNRMPGK-MGLFLGLTAYHMNAA 215 Query: 188 IMCENGF 194 C G Sbjct: 216 DACYVGL 222 >3M6N-A nrPDB Length = 305 Score = 66.8 bits (161), Expect = 1e-11, Method: Composition-based stats. Identities = 16/144 (11%), Positives = 42/144 (29%), Gaps = 5/144 (3%) Query: 57 TIIQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLI 116 ++ S F+ G D + + + + R V+ + I Sbjct: 89 VVLASDSDVFNLGGDLALFCQLIREGDRARLLD----YAQRCVRGVHAFHVGLGARAHSI 144 Query: 117 CCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYE 176 + G A+G C + + + V + P L G + + + + Sbjct: 145 ALVQGNALGGGFEAALSCHTIIA-EEGVMMGLPEVLFDLFPGMGAYSFMCQRISAHLAQK 203 Query: 177 CLMFNKPFKYDIMCENGFISKNFN 200 ++ + + + G + + Sbjct: 204 IMLEGNLYSAEQLLGMGLVDRVVP 227 >3VZ3-A nrPDB Length = 457 Score = 33.3 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 21/162 (12%), Positives = 48/162 (29%), Gaps = 19/162 (11%) Query: 36 EDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVS 95 + + +E ++ V + S +GA +A + T + Sbjct: 184 QTLLIGASQVEQVIKDPRVKAATLTGSEP---AGASLASLAGQEIKPTLLELGGSDP--- 237 Query: 96 NFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVYL--------- 146 FV D ++ V NG + + + I +K++L Sbjct: 238 -FVVFPSADLDEAVEVGTVARTMNNGQSAIAAKRFILHEAIAAEFLEKLHLKFASLKIGD 296 Query: 147 -LYPFANLGLITEGGTTVSLPLKFGTNTT--YECLMFNKPFK 185 + P ++G + G + + + L+ +P Sbjct: 297 PMAPETDIGPLATEGILQDISRQVDQAVAAGAKILLGGRPLD 338 >4PZ2-A nrPDB Length = 534 Score = 32.9 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 27/252 (10%), Positives = 63/252 (25%), Gaps = 23/252 (9%) Query: 36 EDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVS 95 + L + + + ++ + A A + ++ Sbjct: 123 DLVEEHAGELAALESLDAGKHPAVTRAVDVGNAAGSLRYFAGAADKIHGETLKMPGQFQG 182 Query: 96 NFVARNVYVTDAFIKHSKV--LICCLNGPAIGLSAALVAL------CDIVYSINDKVYLL 147 + + + V I + + PA+ ALV +Y Sbjct: 183 HTLREPLGVAGVIIPWNFPSTMFAVKVAPALAAGCALVVKPAEQTPLSALYLAQLAKQAG 242 Query: 148 YPFANLGLITEGGTTVSLPLK----------FGTNTTYECLMFNKPFKYDIMCENGFISK 197 P + ++ G T L G+ +M + + ++ Sbjct: 243 VPDGVINVVPGFGPTAGAALASHMDVDMVSFTGSTEVGRLIM---KASAESNLKPVYLEL 299 Query: 198 NFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVNESLK 257 P + + + EL V + + + + E ++ Sbjct: 300 GGKSPLIVFDDADLDMAVELA--VGASFFNKGEACVAASRVYVQERVYDRFEERLAERMR 357 Query: 258 YWVDGEPLKRFR 269 WV G+P R Sbjct: 358 SWVVGDPFSDPR 369 >1UM9-A nrPDB Length = 367 Score = 30.6 bits (67), Expect = 0.88, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 34/86 (39%), Gaps = 4/86 (4%) Query: 186 YDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFN 245 D G + + + A + V++E E+ + PS + ++ H A + Sbjct: 222 ADKAHAFGIPG--YLVDGMDVLA-SYYVVKEAVERARRGEGPSLVELRVYRYGPHSSADD 278 Query: 246 KANSVEVNESLKYWVDGEPLKRFRQL 271 + E + +W +P+ RFR+ Sbjct: 279 DSRYRP-KEEVAFWRKKDPIPRFRRF 303 >3GTD-A nrPDB Length = 482 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 22/69 (31%), Gaps = 1/69 (1%) Query: 85 KYPSETSKWVSNFVARNVYVTDAFI-KHSKVLICCLNGPAIGLSAALVALCDIVYSINDK 143 P + S ++ + Y + KV + G A+G DI ++ Sbjct: 213 ATPLTLKQEFSGYITQIEYALERIEDALKKVYLLAQGGTAVGTGINSKIGFDIKFAQKVA 272 Query: 144 VYLLYPFAN 152 + PF Sbjct: 273 EFTQQPFKT 281 >3GOL-A nrPDB Length = 581 Score = 29.0 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 20/64 (31%) Query: 50 RNRDVYFTIIQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFI 109 R R V ++ GR + G A P+ + +S + D + Sbjct: 506 RARSVRAKLLSQGGRAATCGRYLFNWAVRTKLKLTPIPAASQLDLSGWFVAGYSGGDIYH 565 Query: 110 KHSK 113 S+ Sbjct: 566 SLSR 569 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.122 0.299 Lambda K H 0.267 0.0371 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,281,322 Number of Sequences: 36641 Number of extensions: 338770 Number of successful extensions: 1168 Number of sequences better than 10.0: 62 Number of HSP's better than 10.0 without gapping: 69 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 975 Number of HSP's gapped (non-prelim): 91 length of query: 280 length of database: 10,336,785 effective HSP length: 96 effective length of query: 184 effective length of database: 6,819,249 effective search space: 1254741816 effective search space used: 1254741816 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (27.1 bits)