BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q05123 (467 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3WEE-A nrPDB 957 0.0 4I6M-B nrPDB 857 0.0 5NBL-C nrPDB 45 7e-05 4PL7-A nrPDB 43 2e-04 5NW4-X nrPDB 42 6e-04 5MVV-A nrPDB 42 7e-04 3QB0-A nrPDB 40 0.003 3ULE-B nrPDB 39 0.005 3MN5-A nrPDB 39 0.006 1C0F-A nrPDB 35 0.075 5NW4-V nrPDB 35 0.099 4CBX-A nrPDB 34 0.11 6F3A-A nrPDB 33 0.34 4AM6-A nrPDB 33 0.36 3QBI-A nrPDB 30 3.2 4I6M-A nrPDB 29 4.7 4D1E-A nrPDB 29 5.1 3DWL-A nrPDB 29 5.1 1K8K-A nrPDB 28 7.1 >3WEE-A nrPDB Length = 476 Score = 957 bits (2474), Expect = 0.0, Method: Compositional matrix adjust. Identities = 466/466 (100%), Positives = 466/466 (100%) Query: 2 APFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNK 61 APFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNK Sbjct: 11 APFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNK 70 Query: 62 AELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQ 121 AELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQ Sbjct: 71 AELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQ 130 Query: 122 SDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLD 181 SDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLD Sbjct: 131 SDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLD 190 Query: 182 HLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENEDE 241 HLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENEDE Sbjct: 191 HLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENEDE 250 Query: 242 DEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQG 301 DEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQG Sbjct: 251 DEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQG 310 Query: 302 CNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLIIE 361 CNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLIIE Sbjct: 311 CNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLIIE 370 Query: 362 PEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWKK 421 PEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWKK Sbjct: 371 PEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWKK 430 Query: 422 SGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF 467 SGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF Sbjct: 431 SGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF 476 >4I6M-B nrPDB Length = 439 Score = 857 bits (2214), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/467 (94%), Positives = 439/467 (94%), Gaps = 28/467 (5%) Query: 1 MAPFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDN 60 MAPFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDN Sbjct: 1 MAPFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDN 60 Query: 61 KAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWS 120 KAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWS Sbjct: 61 KAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWS 120 Query: 121 QSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQL 180 QSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQL Sbjct: 121 QSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQL 180 Query: 181 DHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENED 240 DHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENED Sbjct: 181 DHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENED 240 Query: 241 EDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQ 300 EDEGTL KNSDLEFNTFWDEKGNEIKVGKQRFQ Sbjct: 241 EDEGTL----------------------------KNSDLEFNTFWDEKGNEIKVGKQRFQ 272 Query: 301 GCNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLII 360 GCNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLII Sbjct: 273 GCNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLII 332 Query: 361 EPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWK 420 EPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWK Sbjct: 333 EPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWK 392 Query: 421 KSGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF 467 KSGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF Sbjct: 393 KSGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF 439 >5NBL-C nrPDB Length = 375 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 63/282 (22%), Positives = 111/282 (39%), Gaps = 69/282 (24%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNC-----CIIDV 164 P+LL +S+ E +TQ +FE+ + PA + +++SL + ++D Sbjct: 102 PVLLTEAPMNPKSNREKMTQIMFETFNV------PAFYVSIQAVLSLYSSGRTTGIVLDS 155 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G T ++PI L H + I + G+ + D L K+L ++ S + E++ D Sbjct: 156 GDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKIL----SERGYSFSTTAEREIVRD 211 Query: 225 DAKKLS--SFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFN 282 +KL + DF E + ++S +E Sbjct: 212 IKEKLCYVALDFEQEMQ--------------------------------TAAQSSSIE-K 238 Query: 283 TFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNID----------DINKAKAVWEN 332 ++ G I +G +RF+ L + +GL ID D++ K ++ N Sbjct: 239 SYELPDGQVITIGNERFRAPEALFH--PSVLGLESAGIDQTTYNSIMKCDVDVRKELYGN 296 Query: 333 IIIVGGTTSISGFKE-------ALLGQLLKDHLIIEPEEEKS 367 I++ GGTT G E AL +K +I PE + S Sbjct: 297 IVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYS 338 >4PL7-A nrPDB Length = 440 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 57/261 (21%), Positives = 102/261 (39%), Gaps = 62/261 (23%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISL-----QNCCIIDV 164 P+LL +S+ E +TQ +FE+ + PA + +++SL ++D Sbjct: 102 PVLLTEAPMNPKSNREKMTQIMFETFNV------PAFYVSIQAVLSLYASGRTTGIVLDS 155 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G T ++PI L H + I + G+ + D L K+L ++ + S E++ D Sbjct: 156 GDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKIL----SERGYTFSTSAEREIVRD 211 Query: 225 DAKKLS--SFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFN 282 +KL + DF E + T E+ ++ + Sbjct: 212 IKEKLCYVALDFDQELQ------------------TSSQSSSIEKSYELPD--------- 244 Query: 283 TFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNID----------DINKAKAVWEN 332 G I +G +RF+ L + +GL ID D++ K ++ N Sbjct: 245 ------GQVITIGNERFRAPEALFH--PSVLGLEASGIDQTTYNSIMKCDVDVRKELYSN 296 Query: 333 IIIVGGTTSISGFKEALLGQL 353 I++ GGTT G E + +L Sbjct: 297 IVMSGGTTMFPGIAERMQKEL 317 >5NW4-X nrPDB Length = 417 Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 55/259 (21%), Positives = 118/259 (45%), Gaps = 42/259 (16%) Query: 125 EIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLDHLV 184 E +T+ +F+ E+ +++ P+ L A ++ + + ++D G + ++PI + + + Sbjct: 103 ETLTRVLFKYFEVPSVLLAPSHLMALLTL-GINSAMVLDCGYRESLVLPIYEGIPVLNCW 161 Query: 185 SSIPMGGQSINDSLK-KLLPQWDDDQIESLKKS------PIFEVLSDDAKKLSSFDFGNE 237 ++P+GG++++ L+ +LL Q D + ++S I E + +D K + F Sbjct: 162 GALPLGGKALHKELETQLLEQCTVDTGAAKEQSLPSVMGSIPEGVLEDIKVRTCF----- 216 Query: 238 NEDEDEGT-LNVAEIITSGRDTREV----LEERERGQKVKNVKNS--DLEFNTFWDEKGN 290 D G + A+ G R ++ G+K+ +V S D +++ Sbjct: 217 VSDLTRGLKIQAAKFNIDGNTERPSPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNE 276 Query: 291 EIKVGKQRFQGCNNLIKNISNRVGLTLDNI--DDINKAKAVWENIIIVGGTTSISGFKEA 348 E V L LD++ I+ K + EN++I+GGT+ + GF Sbjct: 277 EKSVAT------------------LILDSLMQCPIDTRKQLAENLVIIGGTSMLPGFLHR 318 Query: 349 LLGQLLKDHLIIEPEEEKS 367 LL ++ +L+ +P+ +K+ Sbjct: 319 LLAEI--RYLVEKPKYKKT 335 >5MVV-A nrPDB Length = 378 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 63/272 (23%), Positives = 111/272 (40%), Gaps = 58/272 (21%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNC-----CIIDV 164 P+LL + + E +TQ +FES + PA A +++SL + ++D Sbjct: 105 PVLLTEAPLNPKGNRERMTQIMFESFNV------PAMYVAIQAVLSLYSSGRTTGIVLDS 158 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G + +PI + L H + + + G+ + + L K+L + S +K E++ D Sbjct: 159 GDGVSHTVPIYEGYALPHAIMRLDLAGRDLTEYLMKILHERGYGFSTSAEK----EIVRD 214 Query: 225 DAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTF 284 +KL N DE+ T + ++SD+E ++ Sbjct: 215 IKEKLCYIAL---NFDEEMKT---------------------------SEQSSDIE-KSY 243 Query: 285 WDEKGNEIKVGKQRFQGCNNLI------KNISNRVGLTLDNID--DINKAKAVWENIIIV 336 GN I VG +RF+ L K + T ++I D++ K ++ NI++ Sbjct: 244 ELPDGNIITVGNERFRCPEALFQPSFLGKEAAGIHTTTFNSIKKCDVDIRKDLYGNIVLS 303 Query: 337 GGTTSISGFKEALLGQLLKDHLIIEPEEEKSK 368 GGTT G E +L +D + P K K Sbjct: 304 GGTTMYEGIGE----RLTRDITTLAPSTMKIK 331 >3QB0-A nrPDB Length = 498 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 48/204 (23%), Positives = 86/204 (42%), Gaps = 29/204 (14%) Query: 8 SILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGS---YTYHSTNKDNKAEL 64 S ++I P S TT + + ++ P+ +P+ + T +G+ ++ S K Sbjct: 24 SAVVIDPGSYTTNIGYSGSD----FPQSILPSVYGKYTADEGNKKIFSEQSIGIPRKDYE 79 Query: 65 IKPI-QNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQSD 123 +KPI +NG +ID + + + L +N S IP LL T W+ ++ Sbjct: 80 LKPIIENGLVIDWDTAQEQWQWALQNELYLNSN----------SGIPALL-TEPVWNSTE 128 Query: 124 -----LEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYA 178 LE++ E ++ P S +++ NC ++D+G + PIVD Sbjct: 129 NRKKSLEVL----LEGMQFEACYLAPTSTCVSFAA-GRPNCLVVDIGHDTCSVSPIVDGM 183 Query: 179 QLDHLVSSIPMGGQSINDSLKKLL 202 L + G+ IN +KK L Sbjct: 184 TLSKSTRRNFIAGKFINHLIKKAL 207 Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust. Identities = 11/34 (32%), Positives = 21/34 (61%) Query: 322 DINKAKAVWENIIIVGGTTSISGFKEALLGQLLK 355 D++ + N+++ GGT+SI G + L+ +L K Sbjct: 406 DVDLRATLAHNVVLTGGTSSIPGLSDRLMTELNK 439 >3ULE-B nrPDB Length = 394 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 72/346 (20%), Positives = 126/346 (36%), Gaps = 88/346 (25%) Query: 125 EIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLDHLV 184 E I + +FE+ + + + ++ Y+ L ++D G T I P+ + L HL Sbjct: 121 EKIVEVMFETYQFSGVYVAIQAVLTLYAQ-GLLTGVVVDSGDGVTHICPVYEGFSLPHLT 179 Query: 185 SSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENEDEDEG 244 + + G+ I L KLL + + S FE + +KL + E E Sbjct: 180 RRLDIAGRDITRYLIKLLLL----RGYAFNHSADFETVRMIKEKLCYVGYNIEQE----- 230 Query: 245 TLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQGCNN 304 QK+ +E T D G IKVG +RF+ Sbjct: 231 ------------------------QKLALETTVLVESYTLPD--GRIIKVGGERFEAPEA 264 Query: 305 LIK-NISNRVGLTLDNI-------DDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKD 356 L + ++ N G+ + + DI+ +++I++ GG+T G L Sbjct: 265 LFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRL------- 317 Query: 357 HLIIEPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYF 416 E+ ++ + VL +K SKF ++ P Sbjct: 318 --------ERELKQLYLERVLKGDVEKLSKFKIR----------IEDP------------ 347 Query: 417 PEWKKSGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAAL 462 P K ++FLG +++ KD F++TR++Y KG L Sbjct: 348 PRRK-----HMVFLGGAVLAD--IMKDKDNFWMTRQEYQEKGVRVL 386 >3MN5-A nrPDB Length = 359 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 60/282 (21%), Positives = 108/282 (38%), Gaps = 69/282 (24%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISL-----QNCCIIDV 164 P LL +++ E +TQ +FE+ + PA A +++SL ++D Sbjct: 86 PTLLTEAPLNPKANREKMTQIMFETFNV------PAMYVAIQAVLSLYASGRTTGIVLDS 139 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G T +PI + L H + + + G+ + D L K+L + + + ++ E++ D Sbjct: 140 GDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAER----EIVRD 195 Query: 225 DAKKLS--SFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFN 282 +KL + DF NE +S LE Sbjct: 196 IKEKLCYVALDFENE--------------------------------MATAASSSSLE-K 222 Query: 283 TFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNID----------DINKAKAVWEN 332 ++ G I +G +RF+ L + + +G+ I DI+ K ++ N Sbjct: 223 SYELPDGQVITIGNERFRCPETLFQ--PSFIGMESAGIHETTYNSIMKCDIDIRKDLYAN 280 Query: 333 IIIVGGTTSISGFKE-------ALLGQLLKDHLIIEPEEEKS 367 ++ GGTT G + AL +K +I PE + S Sbjct: 281 NVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYS 322 >1C0F-A nrPDB Length = 368 Score = 35.0 bits (79), Expect = 0.075, Method: Compositional matrix adjust. Identities = 59/282 (20%), Positives = 112/282 (39%), Gaps = 69/282 (24%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISL-----QNCCIIDV 164 P+LL +++ E +TQ +FE+ PA A +++SL ++D Sbjct: 95 PVLLTEAPLNPKANREKMTQIMFETF------NTPAMYVAIQAVLSLYASGRTTGIVMDS 148 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G + +PI + L H + + + G+ + D + K+L ++ S + E++ D Sbjct: 149 GDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYMMKIL----TERGYSFTTTAEREIVRD 204 Query: 225 DAKKLS--SFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFN 282 +KL+ + DF AE+ T+ +S LE Sbjct: 205 IKEKLAYVALDF-------------EAEMQTA-------------------ASSSALE-K 231 Query: 283 TFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNID----------DINKAKAVWEN 332 ++ G I +G +RF+ L + + +G+ I D++ K ++ N Sbjct: 232 SYELPDGQVITIGNERFRCPEALFQ--PSFLGMESAGIHETTYNSIMKCDVDIRKDLYGN 289 Query: 333 IIIVGGTTSISGFKE-------ALLGQLLKDHLIIEPEEEKS 367 +++ GGTT G + AL +K +I PE + S Sbjct: 290 VVLSGGTTMFPGIADRMNKELTALAPSTMKIKIIAPPERKYS 331 >5NW4-V nrPDB Length = 396 Score = 34.7 bits (78), Expect = 0.099, Method: Compositional matrix adjust. Identities = 60/282 (21%), Positives = 109/282 (38%), Gaps = 69/282 (24%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISL-----QNCCIIDV 164 P+LL +++ E +TQ +FE+ PA A +++SL ++D Sbjct: 123 PVLLTEAPLNPKANREKMTQIMFETFNT------PAMYVAIQAVLSLYASGRTTGIVMDS 176 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G T +PI + L H + + + G+ + D L K+L ++ S + E++ D Sbjct: 177 GDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKIL----TERGYSFTTTAEREIVRD 232 Query: 225 DAKKLS--SFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFN 282 +KL + DF E +S LE Sbjct: 233 IKEKLCYVALDFEQE--------------------------------MATAASSSSLE-K 259 Query: 283 TFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGL--------TLDNI--DDINKAKAVWEN 332 ++ G I +G +RF+ L + + +G+ T ++I D++ K ++ N Sbjct: 260 SYELPDGQVITIGNERFRCPEALFQ--PSFLGMESCGIHETTFNSIMKCDVDIRKDLYAN 317 Query: 333 IIIVGGTTSISGFKE-------ALLGQLLKDHLIIEPEEEKS 367 ++ GGTT G + AL +K +I PE + S Sbjct: 318 TVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYS 359 >4CBX-A nrPDB Length = 378 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 60/279 (21%), Positives = 108/279 (38%), Gaps = 62/279 (22%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISL-----QNCCIIDV 164 P+LL +++ E +TQ +FES ++ PA + +++SL ++D Sbjct: 104 PVLLTEAPLNPKTNREKMTQIMFESFDV------PAMYVSIQAILSLYASGRTTGIVLDS 157 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G T +PI + L H ++ M G+ + + KL + + ++ E++ D Sbjct: 158 GDGVTHTVPIYEGYVLPHAINRTDMAGRDLTYYMMKLFTERGYTFTTTAER----EIVRD 213 Query: 225 DAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTF 284 +KL D DE + K+ + ++ + Sbjct: 214 IKEKLCYIAL-----DYDE-------------------------ELKKSEERTEEVEEMY 243 Query: 285 WDEKGNEIKVGKQRFQGCNNLIKNIS----NRVGLTLDNIDDINKA-----KAVWENIII 335 GN I VG +RF+ C + N S GL + I K K ++ NI++ Sbjct: 244 ELPDGNLITVGSERFR-CPEALFNPSLIGRECPGLHITAYQSIMKCDIDIRKELYNNIVL 302 Query: 336 VGGTTSISGFKEALLGQL-------LKDHLIIEPEEEKS 367 GGTT + E L ++ +K +I PE + S Sbjct: 303 SGGTTMYNYIGERLTNEMTSLAPPSMKIKVIAPPERKYS 341 >6F3A-A nrPDB Length = 376 Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust. Identities = 51/261 (19%), Positives = 100/261 (38%), Gaps = 62/261 (23%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNL---IQLPASLAATYSMISLQNCCIIDVGT 166 P+LL + + E + FE+ + L +Q SL AT ++D G Sbjct: 107 PVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYAT----GRTTGVVLDSGD 162 Query: 167 HHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDA 226 T +PI + + H + I + G+ ++ L+ L Sbjct: 163 GVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYL------------------------ 198 Query: 227 KKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNT--F 284 + +DF + +E EI+ + ++ER + K+ LE + Sbjct: 199 -RKEGYDFHSSSE---------FEIVKA-------IKERACYLSINPQKDETLETEKAQY 241 Query: 285 WDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNI----------DDINKAKAVWENII 334 + G+ I++G RF+ L + + +G + I D++ + ++ NI+ Sbjct: 242 YLPDGSTIEIGPSRFRAPELLFR--PDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIV 299 Query: 335 IVGGTTSISGFKEALLGQLLK 355 + GG+T GF + LL ++ K Sbjct: 300 LSGGSTLFKGFGDRLLSEVKK 320 >4AM6-A nrPDB Length = 655 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 35/171 (20%), Positives = 68/171 (39%), Gaps = 16/171 (9%) Query: 48 DGSYTYHSTNK----DNKAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFE 103 D S Y+ ++ D K + KP + G S + + L ++SD + A Sbjct: 153 DDSKLYYGSDALRCVDEKFVIRKPFRGGSFNVKSPYYKSL----AELISDVTKLLEHALN 208 Query: 104 AELSNIP--------LLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMIS 155 +E N+ ++L+ + +S +E + + L+ + + SLA Y Sbjct: 209 SETLNVKPTKFNQYKVVLVIPDIFKKSHVETFIRVLLTELQFQAVAIIQESLATCYGAGI 268 Query: 156 LQNCCIIDVGTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWD 206 + C++++G T I + + L+H ++ GG I L Q D Sbjct: 269 STSTCVVNIGAAETRIACVDEGTVLEHSAITLDYGGDDITRLFALFLLQSD 319 >3QBI-A nrPDB Length = 291 Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust. Identities = 11/33 (33%), Positives = 21/33 (63%) Query: 108 NIPLLLITHHSWSQSDLEIITQYVFESLEINNL 140 + +L + + SW+ S L+I+ +Y+F L +N L Sbjct: 235 GVAVLPVGYTSWAYSALDIVAKYIFAFLLLNYL 267 >4I6M-A nrPDB Length = 477 Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust. Identities = 42/197 (21%), Positives = 78/197 (39%), Gaps = 33/197 (16%) Query: 10 LIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNKAELIKPIQ 69 ++I+ S T+ F E +P+ IP+ + T + G +AE I Sbjct: 8 VVIHNGSHRTVAGFSNVE----LPQCIIPSSYIKRTDEGG-----------EAEFIFGTY 52 Query: 70 NGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAEL------------SNIPLLLITHH 117 N +ID +A + ++ + S N DA E + +PL++ Sbjct: 53 N--MIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPA 110 Query: 118 SWSQSDLEIITQY---VFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPI 174 + + D+ I+ +Y F+ L + + LA SM + +ID+G ++ PI Sbjct: 111 TNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSM-GKSSAFVIDIGASGCNVTPI 169 Query: 175 VDYAQLDHLVSSIPMGG 191 +D + + V GG Sbjct: 170 IDGIVVKNAVVRSKFGG 186 >4D1E-A nrPDB Length = 876 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 23/96 (23%), Positives = 38/96 (39%), Gaps = 20/96 (20%) Query: 115 THHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPI 174 TH +W+ +I+ Q +ES ASL +++ D+ H + I Sbjct: 394 THETWAYGKEQILLQKDYES----------ASLTEVRALLRKHEAFESDLAAHQDRVEQI 443 Query: 175 VDYAQ----LDHLVSSIPMGGQSINDSLKKLLPQWD 206 AQ LD+ ++ND +K+ QWD Sbjct: 444 AAIAQELNELDY------HDAVNVNDRCQKICDQWD 473 >3DWL-A nrPDB Length = 427 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 43/179 (24%), Positives = 74/179 (41%), Gaps = 23/179 (12%) Query: 161 IIDVGTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLL-----PQWDDDQIESLKK 215 ++D G T IIP+ + + + ++P+ G+ + ++ LL P E +K+ Sbjct: 183 VVDSGDGVTHIIPVAEGYVIGSSIKTMPLAGRDVTYFVQSLLRDRNEPDSSLKTAERIKE 242 Query: 216 SPIFEVLSDDAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKV-KNV 274 + V D K+ S FD + D +E IT T +V ER ++ N Sbjct: 243 ECCY-VCPDIVKEFSRFD-----REPDRYLKYASESITGHSTTIDVGFERFLAPEIFFNP 296 Query: 275 KNSDLEFNTFWDE------KGNEIKVGKQRFQ-----GCNNLIKNISNRVGLTLDNIDD 322 + + +F T E + + I V K ++ G + L KN NR+ L I D Sbjct: 297 EIASSDFLTPLPELVDNVVQSSPIDVRKGLYKNIVLSGGSTLFKNFGNRLQRDLKRIVD 355 >1K8K-A nrPDB Length = 418 Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust. Identities = 36/143 (25%), Positives = 60/143 (41%), Gaps = 18/143 (12%) Query: 67 PIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQSDLEI 126 PI++G + D +F+ + L RA F L+ PL + + E Sbjct: 77 PIRHGIVEDWDLMERFMEQVIFKYL--RAEPEDHYFL--LTEPPLN-------TPENREY 125 Query: 127 ITQYVFESLEINNL-IQLPASLAATYSMISLQ------NCCIIDVGTHHTDIIPIVDYAQ 179 + +FES + L I + A LA S S Q +ID G T +IP+ + Sbjct: 126 TAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYV 185 Query: 180 LDHLVSSIPMGGQSINDSLKKLL 202 + + IP+ G+ I +++LL Sbjct: 186 IGSCIKHIPIAGRDITYFIQQLL 208 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3WEE-A nrPDB 787 0.0 4I6M-B nrPDB 729 0.0 5NBL-C nrPDB 257 8e-69 5MVV-A nrPDB 251 5e-67 4PL7-A nrPDB 246 2e-65 5NW4-X nrPDB 238 4e-63 Sequences not found previously or not previously below threshold: 5NW4-V nrPDB 240 8e-64 3MN5-A nrPDB 237 6e-63 1C0F-A nrPDB 237 1e-62 4CBX-A nrPDB 214 6e-56 3ULE-B nrPDB 177 1e-44 6F3A-A nrPDB 165 4e-41 1K8K-A nrPDB 111 9e-25 3DWL-A nrPDB 101 8e-22 3QB0-A nrPDB 66 5e-11 6GEJ-R nrPDB 64 9e-11 6HTS-H nrPDB 61 1e-09 4I6M-A nrPDB 49 4e-06 4AM6-A nrPDB 45 7e-05 6J79-A nrPDB 35 0.074 4DCL-A nrPDB 32 0.40 3IFS-A nrPDB 32 0.56 4IQF-A nrPDB 30 2.3 3ZNC-A nrPDB 29 3.3 6C96-A nrPDB 29 3.3 5MQC-B nrPDB 29 3.5 1ZXJ-A nrPDB 29 5.8 >3WEE-A nrPDB Length = 476 Score = 787 bits (2032), Expect = 0.0, Method: Composition-based stats. Identities = 466/466 (100%), Positives = 466/466 (100%) Query: 2 APFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNK 61 APFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNK Sbjct: 11 APFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNK 70 Query: 62 AELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQ 121 AELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQ Sbjct: 71 AELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQ 130 Query: 122 SDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLD 181 SDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLD Sbjct: 131 SDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLD 190 Query: 182 HLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENEDE 241 HLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENEDE Sbjct: 191 HLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENEDE 250 Query: 242 DEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQG 301 DEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQG Sbjct: 251 DEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQG 310 Query: 302 CNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLIIE 361 CNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLIIE Sbjct: 311 CNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLIIE 370 Query: 362 PEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWKK 421 PEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWKK Sbjct: 371 PEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWKK 430 Query: 422 SGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF 467 SGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF Sbjct: 431 SGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF 476 >4I6M-B nrPDB Length = 439 Score = 729 bits (1882), Expect = 0.0, Method: Composition-based stats. Identities = 439/467 (94%), Positives = 439/467 (94%), Gaps = 28/467 (5%) Query: 1 MAPFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDN 60 MAPFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDN Sbjct: 1 MAPFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDN 60 Query: 61 KAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWS 120 KAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWS Sbjct: 61 KAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWS 120 Query: 121 QSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQL 180 QSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQL Sbjct: 121 QSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQL 180 Query: 181 DHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENED 240 DHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENED Sbjct: 181 DHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENED 240 Query: 241 EDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQ 300 EDEGTL KNSDLEFNTFWDEKGNEIKVGKQRFQ Sbjct: 241 EDEGTL----------------------------KNSDLEFNTFWDEKGNEIKVGKQRFQ 272 Query: 301 GCNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLII 360 GCNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLII Sbjct: 273 GCNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLII 332 Query: 361 EPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWK 420 EPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWK Sbjct: 333 EPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWK 392 Query: 421 KSGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF 467 KSGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF Sbjct: 393 KSGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF 439 >5NBL-C nrPDB Length = 375 Score = 257 bits (656), Expect = 8e-69, Method: Composition-based stats. Identities = 60/282 (21%), Positives = 110/282 (39%), Gaps = 69/282 (24%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNC-----CIIDV 164 P+LL +S+ E +TQ +FE+ + PA + +++SL + ++D Sbjct: 102 PVLLTEAPMNPKSNREKMTQIMFETFNV------PAFYVSIQAVLSLYSSGRTTGIVLDS 155 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G T ++PI L H + I + G+ + D L K+L ++ S + E++ D Sbjct: 156 GDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKIL----SERGYSFSTTAEREIVRD 211 Query: 225 DAKKLSS--FDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFN 282 +KL DF E + ++S +E Sbjct: 212 IKEKLCYVALDFEQEMQ--------------------------------TAAQSSSIE-K 238 Query: 283 TFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNI----------DDINKAKAVWEN 332 ++ G I +G +RF+ L + +GL I D++ K ++ N Sbjct: 239 SYELPDGQVITIGNERFRAPEALFH--PSVLGLESAGIDQTTYNSIMKCDVDVRKELYGN 296 Query: 333 IIIVGGTTSISGFKEALLGQL-------LKDHLIIEPEEEKS 367 I++ GGTT G E + ++ +K +I PE + S Sbjct: 297 IVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYS 338 >5MVV-A nrPDB Length = 378 Score = 251 bits (641), Expect = 5e-67, Method: Composition-based stats. Identities = 62/278 (22%), Positives = 111/278 (39%), Gaps = 61/278 (21%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNC-----CIIDV 164 P+LL + + E +TQ +FES + PA A +++SL + ++D Sbjct: 105 PVLLTEAPLNPKGNRERMTQIMFESFNV------PAMYVAIQAVLSLYSSGRTTGIVLDS 158 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G + +PI + L H + + + G+ + + L K+L ++ S E++ D Sbjct: 159 GDGVSHTVPIYEGYALPHAIMRLDLAGRDLTEYLMKILH----ERGYGFSTSAEKEIVRD 214 Query: 225 DAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTF 284 +KL N DE+ T + ++SD+E ++ Sbjct: 215 IKEKLCYIAL---NFDEEMKT---------------------------SEQSSDIE-KSY 243 Query: 285 WDEKGNEIKVGKQRFQGCNNLI------KNISNRVGLTLDNI--DDINKAKAVWENIIIV 336 GN I VG +RF+ L K + T ++I D++ K ++ NI++ Sbjct: 244 ELPDGNIITVGNERFRCPEALFQPSFLGKEAAGIHTTTFNSIKKCDVDIRKDLYGNIVLS 303 Query: 337 GGTTSISGFKEA-------LLGQLLKDHLIIEPEEEKS 367 GGTT G E L +K ++ PE + S Sbjct: 304 GGTTMYEGIGERLTRDITTLAPSTMKIKVVAPPERKYS 341 >4PL7-A nrPDB Length = 440 Score = 246 bits (627), Expect = 2e-65, Method: Composition-based stats. Identities = 58/282 (20%), Positives = 105/282 (37%), Gaps = 69/282 (24%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQ-----NCCIIDV 164 P+LL +S+ E +TQ +FE+ + PA + +++SL ++D Sbjct: 102 PVLLTEAPMNPKSNREKMTQIMFETFNV------PAFYVSIQAVLSLYASGRTTGIVLDS 155 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G T ++PI L H + I + G+ + D L K+L ++ + S E++ D Sbjct: 156 GDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKIL----SERGYTFSTSAEREIVRD 211 Query: 225 DAKKLSS--FDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFN 282 +KL DF E + + + Sbjct: 212 IKEKLCYVALDFDQELQTSSQSS---------------------------------SIEK 238 Query: 283 TFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNI----------DDINKAKAVWEN 332 ++ G I +G +RF+ L + +GL I D++ K ++ N Sbjct: 239 SYELPDGQVITIGNERFRAPEALFH--PSVLGLEASGIDQTTYNSIMKCDVDVRKELYSN 296 Query: 333 IIIVGGTTSISGFKEALLGQL-------LKDHLIIEPEEEKS 367 I++ GGTT G E + +L +K + PE + S Sbjct: 297 IVMSGGTTMFPGIAERMQKELTALAPSSMKVKISAPPERKYS 338 >5NW4-V nrPDB Length = 396 Score = 240 bits (613), Expect = 8e-64, Method: Composition-based stats. Identities = 54/278 (19%), Positives = 104/278 (37%), Gaps = 61/278 (21%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQ-----NCCIIDV 164 P+LL +++ E +TQ +FE+ PA A +++SL ++D Sbjct: 123 PVLLTEAPLNPKANREKMTQIMFETFN------TPAMYVAIQAVLSLYASGRTTGIVMDS 176 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G T +PI + L H + + + G+ + D L K+L ++ S + E++ D Sbjct: 177 GDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKIL----TERGYSFTTTAEREIVRD 232 Query: 225 DAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTF 284 +KL E Q++ +S ++ Sbjct: 233 IKEKLCYVALDFE-------------------------------QEMATAASSSSLEKSY 261 Query: 285 WDEKGNEIKVGKQRFQGCNNLIK------NISNRVGLTLDNI--DDINKAKAVWENIIIV 336 G I +G +RF+ L + T ++I D++ K ++ N ++ Sbjct: 262 ELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLS 321 Query: 337 GGTTSISGFKEALLGQL-------LKDHLIIEPEEEKS 367 GGTT G + + ++ +K +I PE + S Sbjct: 322 GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYS 359 >5NW4-X nrPDB Length = 417 Score = 238 bits (607), Expect = 4e-63, Method: Composition-based stats. Identities = 56/273 (20%), Positives = 122/273 (44%), Gaps = 42/273 (15%) Query: 111 LLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTD 170 +++I E +T+ +F+ E+ +++ P+ L A + + + + ++D G + Sbjct: 89 VVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLT-LGINSAMVLDCGYRESL 147 Query: 171 IIPIVDYAQLDHLVSSIPMGGQSINDSLK-KLLPQWDDDQIESLKKS------PIFEVLS 223 ++PI + + + ++P+GG++++ L+ +LL Q D + ++S I E + Sbjct: 148 VLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKEQSLPSVMGSIPEGVL 207 Query: 224 DDAKKLSSFDFGNENEDEDEGT-LNVAEIITSGRDTREV----LEERERGQKVKNVKNS- 277 +D K + F D G + A+ G R ++ G+K+ +V S Sbjct: 208 EDIKVRTCF-----VSDLTRGLKIQAAKFNIDGNTERPSPPPNVDYPLDGEKILHVLGSI 262 Query: 278 -DLEFNTFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNI--DDINKAKAVWENII 334 D +++ E V L LD++ I+ K + EN++ Sbjct: 263 RDSVVEILFEQDNEEKSVAT------------------LILDSLMQCPIDTRKQLAENLV 304 Query: 335 IVGGTTSISGFKEALLGQLLKDHLIIEPEEEKS 367 I+GGT+ + GF LL ++ +L+ +P+ +K+ Sbjct: 305 IIGGTSMLPGFLHRLLAEI--RYLVEKPKYKKT 335 >3MN5-A nrPDB Length = 359 Score = 237 bits (605), Expect = 6e-63, Method: Composition-based stats. Identities = 56/278 (20%), Positives = 105/278 (37%), Gaps = 61/278 (21%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQ-----NCCIIDV 164 P LL +++ E +TQ +FE+ + PA A +++SL ++D Sbjct: 86 PTLLTEAPLNPKANREKMTQIMFETFNV------PAMYVAIQAVLSLYASGRTTGIVLDS 139 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G T +PI + L H + + + G+ + D L K+L ++ S + E++ D Sbjct: 140 GDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL----TERGYSFVTTAEREIVRD 195 Query: 225 DAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTF 284 +KL ENE + +S ++ Sbjct: 196 IKEKLCYVALDFENE-------------------------------MATAASSSSLEKSY 224 Query: 285 WDEKGNEIKVGKQRFQGCNNLIK------NISNRVGLTLDNI--DDINKAKAVWENIIIV 336 G I +G +RF+ L + + T ++I DI+ K ++ N ++ Sbjct: 225 ELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMS 284 Query: 337 GGTTSISGFKEALLGQL-------LKDHLIIEPEEEKS 367 GGTT G + + ++ +K +I PE + S Sbjct: 285 GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYS 322 >1C0F-A nrPDB Length = 368 Score = 237 bits (603), Expect = 1e-62, Method: Composition-based stats. Identities = 53/278 (19%), Positives = 106/278 (38%), Gaps = 61/278 (21%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQ-----NCCIIDV 164 P+LL +++ E +TQ +FE+ PA A +++SL ++D Sbjct: 95 PVLLTEAPLNPKANREKMTQIMFETFN------TPAMYVAIQAVLSLYASGRTTGIVMDS 148 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G + +PI + L H + + + G+ + D + K+L ++ S + E++ D Sbjct: 149 GDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYMMKIL----TERGYSFTTTAEREIVRD 204 Query: 225 DAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTF 284 +KL+ E E + +S ++ Sbjct: 205 IKEKLAYVALDFEAEMQT-------------------------------AASSSALEKSY 233 Query: 285 WDEKGNEIKVGKQRFQGCNNLIK------NISNRVGLTLDNI--DDINKAKAVWENIIIV 336 G I +G +RF+ L + + T ++I D++ K ++ N+++ Sbjct: 234 ELPDGQVITIGNERFRCPEALFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYGNVVLS 293 Query: 337 GGTTSISGFKEALLGQL-------LKDHLIIEPEEEKS 367 GGTT G + + +L +K +I PE + S Sbjct: 294 GGTTMFPGIADRMNKELTALAPSTMKIKIIAPPERKYS 331 >4CBX-A nrPDB Length = 378 Score = 214 bits (545), Expect = 6e-56, Method: Composition-based stats. Identities = 63/333 (18%), Positives = 121/333 (36%), Gaps = 71/333 (21%) Query: 55 STNKDNKAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLI 114 + NK L PI++G + + + R F + L ++ P+LL Sbjct: 60 AQNKRGILTLKYPIEHGIVTNWDDMEKIWRHTFFNELRVSPEEH-----------PVLLT 108 Query: 115 THHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQ-----NCCIIDVGTHHT 169 +++ E +TQ +FES ++ PA + +++SL ++D G T Sbjct: 109 EAPLNPKTNREKMTQIMFESFDV------PAMYVSIQAILSLYASGRTTGIVLDSGDGVT 162 Query: 170 DIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKL 229 +PI + L H ++ M G+ + + KL ++ + + E++ D +KL Sbjct: 163 HTVPIYEGYVLPHAINRTDMAGRDLTYYMMKLF----TERGYTFTTTAEREIVRDIKEKL 218 Query: 230 SSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKG 289 + K+ + ++ + G Sbjct: 219 CYIALD------------------------------YDEELKKSEERTEEVEEMYELPDG 248 Query: 290 NEIKVGKQRFQGCNNLI------KNISNRVGLTLDNI--DDINKAKAVWENIIIVGGTTS 341 N I VG +RF+ L + +I DI+ K ++ NI++ GGTT Sbjct: 249 NLITVGSERFRCPEALFNPSLIGRECPGLHITAYQSIMKCDIDIRKELYNNIVLSGGTTM 308 Query: 342 ISGFKEALLGQL-------LKDHLIIEPEEEKS 367 + E L ++ +K +I PE + S Sbjct: 309 YNYIGERLTNEMTSLAPPSMKIKVIAPPERKYS 341 >3ULE-B nrPDB Length = 394 Score = 177 bits (448), Expect = 1e-44, Method: Composition-based stats. Identities = 70/364 (19%), Positives = 126/364 (34%), Gaps = 98/364 (26%) Query: 108 NIPLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQ-----NCCII 162 N +LL + E I + +FE+ + + + A ++++L ++ Sbjct: 104 NCKILLTEPPMNPTKNREKIVEVMFETYQFSGV------YVAIQAVLTLYAQGLLTGVVV 157 Query: 163 DVGTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVL 222 D G T I P+ + L HL + + G+ I L KLL + + S FE + Sbjct: 158 DSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLL----RGYAFNHSADFETV 213 Query: 223 SDDAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFN 282 +KL + E Q+ K + + Sbjct: 214 RMIKEKLCYVGYNIE-------------------------------QEQKLALETTVLVE 242 Query: 283 TFWDEKGNEIKVGKQRFQGCNNLIK------NISNRVGLTLDNID--DINKAKAVWENII 334 ++ G IKVG +RF+ L + L + I DI+ +++I+ Sbjct: 243 SYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIV 302 Query: 335 IVGGTTSISGFKEALLGQLLKDHLIIEPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAF 394 + GG+T G L +L + +L + VL +K SKF Sbjct: 303 LSGGSTMYPGLPSRLERELKQLYL---------------ERVLKGDVEKLSKFK------ 341 Query: 395 VPTIEYVQCPTVIKLAKYPDYFPEWKKSGYSEIIFLGAQIVSKQIFTHPKDTFYITREKY 454 I++ P ++FLG +++ KD F++TR++Y Sbjct: 342 ------------IRIEDPPR---------RKHMVFLGGAVLAD--IMKDKDNFWMTRQEY 378 Query: 455 NMKG 458 KG Sbjct: 379 QEKG 382 >6F3A-A nrPDB Length = 376 Score = 165 bits (417), Expect = 4e-41, Method: Composition-based stats. Identities = 47/274 (17%), Positives = 101/274 (36%), Gaps = 66/274 (24%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQ-----NCCIIDV 164 P+LL + + E + FE+ + PA + +++SL ++D Sbjct: 107 PVLLTEAPLNPRKNRERAAEVFFETFNV------PALFISMQAVLSLYATGRTTGVVLDS 160 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 G T +PI + + H + I + G+ ++ L+ L + D S FE++ Sbjct: 161 GDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYD----FHSSSEFEIVKA 216 Query: 225 DAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTF 284 ++ +E +K + + Sbjct: 217 IKERACYLSIN------------------------PQKDETLETEKAQ-----------Y 241 Query: 285 WDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNI----------DDINKAKAVWENII 334 + G+ I++G RF+ L + + +G + I D++ + ++ NI+ Sbjct: 242 YLPDGSTIEIGPSRFRAPELLFR--PDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIV 299 Query: 335 IVGGTTSISGFKEALLGQLLKDHLIIEPEEEKSK 368 + GG+T GF + LL ++ K + P++ K + Sbjct: 300 LSGGSTLFKGFGDRLLSEVKK----LAPKDVKIR 329 >1K8K-A nrPDB Length = 418 Score = 111 bits (276), Expect = 9e-25, Method: Composition-based stats. Identities = 58/306 (18%), Positives = 104/306 (33%), Gaps = 58/306 (18%) Query: 67 PIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQSDLEI 126 PI++G + D +F+ + L RA F LL + + E Sbjct: 77 PIRHGIVEDWDLMERFMEQVIFKYL--RAEPEDHYF---------LLTEPPLNTPENREY 125 Query: 127 ITQYVFESLEINNL-------IQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQ 179 + +FES + L + L AS + +ID G T +IP+ + Sbjct: 126 TAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYV 185 Query: 180 LDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENE 239 + + IP+ G+ I +++LL D + ++S E ++ S Sbjct: 186 IGSCIKHIPIAGRDITYFIQQLL--RDREVGIPPEQS--LETAKAVKERYSYVCPD---- 237 Query: 240 DEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRF 299 V E D + +++ + + S I VG +RF Sbjct: 238 -------LVKEFNKYDTDGSKWIKQYTGINAISKKEFS--------------IDVGYERF 276 Query: 300 QGCNNLIK----------NISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEAL 349 G IS V + N I+ + +++NI++ GG+T F L Sbjct: 277 LGPEIFFHPEFANPDFTQPISEVVDEVIQN-CPIDVRRPLYKNIVLSGGSTMFRDFGRRL 335 Query: 350 LGQLLK 355 L + Sbjct: 336 QRDLKR 341 >3DWL-A nrPDB Length = 427 Score = 101 bits (250), Expect = 8e-22, Method: Composition-based stats. Identities = 53/264 (20%), Positives = 90/264 (34%), Gaps = 58/264 (21%) Query: 112 LLITHHSWSQSDLEIITQYVFESLEINNL-------IQLPASLAATYSMISLQNCCIIDV 164 LL + E + +FES L + L AS ++ ++D Sbjct: 127 LLTEPPLNPPENRENTAEIMFESFNCAGLYIAVQAVLALAASWTSSKVTDRSLTGTVVDS 186 Query: 165 GTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFE---- 220 G T IIP+ + + + ++P+ G+ + ++ LL ++ I E Sbjct: 187 GDGVTHIIPVAEGYVIGSSIKTMPLAGRDVTYFVQSLLRDRNEPDSSLKTAERIKEECCY 246 Query: 221 VLSDDAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLE 280 V D K+ S FD + D +E IT T Sbjct: 247 VCPDIVKEFSRFD-----REPDRYLKYASESITGHSTT---------------------- 279 Query: 281 FNTFWDEKGNEIKVGKQRFQGCNNLIK-NISNRVGLT-----LDNI---DDINKAKAVWE 331 I VG +RF I++ LT +DN+ I+ K +++ Sbjct: 280 -----------IDVGFERFLAPEIFFNPEIASSDFLTPLPELVDNVVQSSPIDVRKGLYK 328 Query: 332 NIIIVGGTTSISGFKEALLGQLLK 355 NI++ GG+T F L L + Sbjct: 329 NIVLSGGSTLFKNFGNRLQRDLKR 352 >3QB0-A nrPDB Length = 498 Score = 65.6 bits (158), Expect = 5e-11, Method: Composition-based stats. Identities = 75/437 (17%), Positives = 137/437 (31%), Gaps = 110/437 (25%) Query: 8 SILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGS---YTYHSTNKDNKAEL 64 S ++I P S TT + + ++ P+ +P+ + T +G+ ++ S K Sbjct: 24 SAVVIDPGSYTTNIGYSGSD----FPQSILPSVYGKYTADEGNKKIFSEQSIGIPRKDYE 79 Query: 65 IKPI-QNGEIIDISAFTQFLRLIFVSILSDRANKN-QDAFEAEL-----SNIPLLLITHH 117 +KPI +NG +ID D A + Q A + EL S IP LL Sbjct: 80 LKPIIENGLVIDW----------------DTAQEQWQWALQNELYLNSNSGIPALLTEPV 123 Query: 118 SWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDY 177 S + + + + E ++ P S +++ NC ++D+G + PIVD Sbjct: 124 WNSTENRKKSLEVLLEGMQFEACYLAPTSTCVSFAA-GRPNCLVVDIGHDTCSVSPIVDG 182 Query: 178 AQLDHLVSSIPMGG---------------------------------------QSINDSL 198 L + G +S+ D Sbjct: 183 MTLSKSTRRNFIAGKFINHLIKKALEPKEIIPLFAIKQRKPEFIKKTFDYEVDKSLYDYA 242 Query: 199 ------------------KKLLPQWDDDQIESLKKS---PIFEVLSDDAKKLSSFDFGNE 237 K L + + + K+S P E + D + F Sbjct: 243 NNRGFFQECKETLCHICPTKTLEETKTELSSTAKRSIESPWNEEIVFDNETRYGFAEELF 302 Query: 238 NEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQ 297 ED+ N + T + K V SD + +++ + Sbjct: 303 LPKEDDIPANWPRSNSGVVKTWRNDYVPLKRTKPSGVNKSDKKVTPTEEKEQEAVSKSTS 362 Query: 298 -----------------RFQGCNNLIKNISNRVGLTLDNI--DDINKAKAVWENIIIVGG 338 + + L +I D++ + N+++ GG Sbjct: 363 PAANSADTPNETGKRPLEEEKPPKENNELIGLADLVYSSIMSSDVDLRATLAHNVVLTGG 422 Query: 339 TTSISGFKEALLGQLLK 355 T+SI G + L+ +L K Sbjct: 423 TSSIPGLSDRLMTELNK 439 >6GEJ-R nrPDB Length = 438 Score = 64.4 bits (155), Expect = 9e-11, Method: Composition-based stats. Identities = 33/204 (16%), Positives = 63/204 (30%), Gaps = 25/204 (12%) Query: 160 CIIDVGTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIF 219 +ID G + T IIP++ V + +GG+ + LK+ L + ++ Sbjct: 189 LVIDSGFNCTWIIPVLKGIPYYKAVKKLDIGGRFLTGLLKETLSFRHYNMMDE------- 241 Query: 220 EVLSDDAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDL 279 +L ++ K+ F D + A L +K Sbjct: 242 TILVNNIKEQCLFVSPVSYFDSFKTKDKHALEYVLPDFQTSFLGYVRNPRK--------- 292 Query: 280 EFNTFWDEKGNEIKVGKQRFQGCNNLIK------NISNRVGLTLDNID--DINKAKAVWE 331 N E I + + F V L+++ + Sbjct: 293 -ENVPLPEDAQIITLTDELFTIPETFFHPEISQITKPGIVEAILESLSMLPEIVRPLMVG 351 Query: 332 NIIIVGGTTSISGFKEALLGQLLK 355 NI+ GG ++ F + L +L + Sbjct: 352 NIVCTGGNFNLPNFAQRLAAELQR 375 >6HTS-H nrPDB Length = 607 Score = 60.6 bits (145), Expect = 1e-09, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 49/118 (41%), Gaps = 3/118 (2%) Query: 110 PLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATY---SMISLQNCCIIDVGT 166 P++L +++++ +FE I + SL + Y S+ + II G Sbjct: 131 PIVLTEAVCNPLYSRQMMSELLFECYGIPKVAYGIDSLFSFYHNKPKNSMCSGLIISSGY 190 Query: 167 HHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSD 224 T ++PI++ I +GG L++LL + ++ S + E+L + Sbjct: 191 QCTHVLPILEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILHE 248 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 30/192 (15%), Positives = 62/192 (32%), Gaps = 35/192 (18%) Query: 196 DSLKKLLPQWDDDQIESLKKSPI------FEVLSDDAKKLSSFDFGNENEDEDEGTLNVA 249 D L + +D Q++ K+ I E L +KLS + + +N+ Sbjct: 325 DRLLYVQELLEDGQMDQFHKALIELNMDSPEELQSYIQKLS-IAVEQAKQKILQAEVNLE 383 Query: 250 EIITSGRDTREVLEERERGQKVKNVKNS----------------DLEFNTFWDEKGNEIK 293 + + LE+ E + N F +++ Sbjct: 384 VDVVDSKPETPDLEQLEPSLEDVESMNDFDPLFSEETPGVEKPVTTVQPVFNLAAYHQLF 443 Query: 294 VGKQRFQGCNNLIKNISNRVGLTLDNID----------DINKAKAVWENIIIVGGTTSIS 343 VG +R + + + + +G I + + + +N+ + GG T Sbjct: 444 VGTERIRAPEIIFQ--PSLIGEEQAGIAETLQYILDRYPKDIQEMLVQNVFLTGGNTMYP 501 Query: 344 GFKEALLGQLLK 355 G K + +LL+ Sbjct: 502 GMKARMEKELLE 513 >4I6M-A nrPDB Length = 477 Score = 49.0 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 69/437 (15%), Positives = 151/437 (34%), Gaps = 101/437 (23%) Query: 10 LIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNKAELIKPIQ 69 ++I+ S T+ F E +P+ IP+ + T + G +AE I Sbjct: 8 VVIHNGSHRTVAGFSNVE----LPQCIIPSSYIKRTDEGG-----------EAEFIFGTY 52 Query: 70 NGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAEL------------SNIPLLLITHH 117 N +ID +A + ++ + S N DA E + +PL++ Sbjct: 53 N--MIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPA 110 Query: 118 SWSQSDLEIITQY---VFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPI 174 + + D+ I+ +Y F+ L + + LA SM + +ID+G ++ PI Sbjct: 111 TNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSM-GKSSAFVIDIGASGCNVTPI 169 Query: 175 VDYAQLDHLVSSIPMGGQ----SINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLS 230 +D + + V GG +++ L L+ + +D + + ++ +V + + + Sbjct: 170 IDGIVVKNAVVRSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQ 229 Query: 231 SFD------FGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEF--N 282 F + + + A+I ++ + ++++ + + N+ L N Sbjct: 230 QFKSTMLQVSEKDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKN 289 Query: 283 TFWDEKGNEIKVG-KQRFQGCNNLIK---------------------------------- 307 + + + K+ +Q L K Sbjct: 290 FLFKPLNKTLTLDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKA 349 Query: 308 ---NISNRVGL--------------TLDNIDDINKAKAVWENIIIVGGTTSISGFKEALL 350 N +G + NI + N+II G T+ I G ++ ++ Sbjct: 350 NTSTNPNGLGTSHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRII 409 Query: 351 GQLLKDHLIIEPEEEKS 367 +L P+ + + Sbjct: 410 KELSIRF----PQYKLT 422 >4AM6-A nrPDB Length = 655 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 41/203 (20%), Positives = 79/203 (38%), Gaps = 18/203 (8%) Query: 16 SQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNK----DNKAELIKPIQNG 71 + +V F N + + E P+ I D S Y+ ++ D K + KP + G Sbjct: 123 AHEQVVSFNENSKPEIISEKNDPSPIEWIF--DDSKLYYGSDALRCVDEKFVIRKPFRGG 180 Query: 72 EIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIP--------LLLITHHSWSQSD 123 S + + L ++SD + A +E N+ ++L+ + +S Sbjct: 181 SFNVKSPYYKSL----AELISDVTKLLEHALNSETLNVKPTKFNQYKVVLVIPDIFKKSH 236 Query: 124 LEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLDHL 183 +E + + L+ + + SLA Y + C++++G T I + + L+H Sbjct: 237 VETFIRVLLTELQFQAVAIIQESLATCYGAGISTSTCVVNIGAAETRIACVDEGTVLEHS 296 Query: 184 VSSIPMGGQSINDSLKKLLPQWD 206 ++ GG I L Q D Sbjct: 297 AITLDYGGDDITRLFALFLLQSD 319 >6J79-A nrPDB Length = 871 Score = 34.8 bits (78), Expect = 0.074, Method: Composition-based stats. Identities = 35/171 (20%), Positives = 63/171 (36%), Gaps = 28/171 (16%) Query: 293 KVGKQRFQGCNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQ 352 +V K+ Q L + T +ID+ K K ++ + K + + Sbjct: 165 QVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYR--ARMNTLEMTPEVKHRVTEE 222 Query: 353 LLKDHLIIEPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKY 412 L+ + EE +++LP K +S T T P K Sbjct: 223 AKTAFLL------NIELFEELQALLPEEHKDQSASQTMQTTAPPV-------------KE 263 Query: 413 PDYFPEWKKSGYSEIIFLGAQIVSKQIFTH--PKDTFYITREKYNMKGPAA 461 + + KK+G + I+F G+Q + + F + KD +Y M+G +A Sbjct: 264 SSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDA-----HRYGMRGMSA 309 >4DCL-A nrPDB Length = 207 Score = 32.5 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 56/155 (36%), Gaps = 14/155 (9%) Query: 199 KKLLPQWDDDQIESLKKSPIFEVLSDDAKKLS-SFDFGNENEDEDEGTLNVAEIITSGRD 257 +K+L + D + ++ I E L AK + + + N + L A T+ + Sbjct: 5 EKMLAEKWYD--ANFDQTLINERLR--AKVICFALNHTNPSATLKRKVLIDALFQTTTDN 60 Query: 258 TREVLEERER-GQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLT 316 + G VK KN + N ++ G +I +G F G N ++ + Sbjct: 61 VSISIPFDTDYGWNVKLGKNVYVNTNCYFM-DGGQITIGDNVFIGPNCGFYTATHPLNFH 119 Query: 317 -----LDNIDDINKAKAVW--ENIIIVGGTTSISG 344 + I+ W ++ ++ G T G Sbjct: 120 HRNEGFEKAGPIHIGSNTWFGGHVAVLPGVTIGEG 154 >3IFS-A nrPDB Length = 453 Score = 32.1 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 37/91 (40%), Gaps = 11/91 (12%) Query: 293 KVGKQRFQGCNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQ 352 + K++ + L N + ++ D+ + K N+I GTT+ + + Sbjct: 106 TLSKEQRKTPQVLF-VGQNISSTYMKDLMDVLEGKDFSINVISKSGTTTEPALAFRIFRK 164 Query: 353 LLKDHLIIEPEEEKSKREEEAKSVLPAATKK 383 LL EE+ K EEA+ + A T K Sbjct: 165 LL--------EEKYGK--EEARKRIYATTDK 185 >4IQF-A nrPDB Length = 317 Score = 30.2 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 32/214 (14%), Positives = 71/214 (33%), Gaps = 16/214 (7%) Query: 97 KNQDAFEAELSNIPLLLITHHSWSQSDLEIITQYVFESLEINNLIQ------LPASLAAT 150 + +D +E L+ P L++T EI+ + + ++ + P A Sbjct: 70 REKDEYEKVLALEPDLIVTAAFGQIVPNEILEAPKYGCINVHASLLPELRGGAPIHYAIM 129 Query: 151 YS-----MISLQNCCIIDVGTHHTDI-IPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQ 204 + + +D G T + + I + L + G + LL Q Sbjct: 130 EGKEKTGITIMYMVEKLDAGDILTQVEVEIEERETTGSLFDKLSEAGAHLLSKTVPLLIQ 189 Query: 205 WDDDQIESLKKSPIFEV-LSDDAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLE 263 + I+ ++ F + + +K+ G E + G + + Sbjct: 190 GKLEPIKQNEEEVTFAYNIKREQEKIDWTKTGEEVYNHIRGL---NPWPVAYTTLAGQVV 246 Query: 264 ERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQ 297 + G+KV K+++ +E G + G + Sbjct: 247 KVWWGEKVPVTKSAEAGTIVAIEEDGFVVATGNE 280 >3ZNC-A nrPDB Length = 258 Score = 29.4 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 359 IIEPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIK--LAKYPDYF 416 I +P + RE + +LP +TK + F N + P + TV K + + + F Sbjct: 162 ISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQF 221 Query: 417 PEWKKSGY 424 E+ K+ Y Sbjct: 222 LEFSKNLY 229 >6C96-A nrPDB Length = 825 Score = 29.4 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 4/79 (5%) Query: 371 EEAKSV-LPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFP---EWKKSGYSE 426 +EA+S LP + + + + +I Q P+++ A P P W+ + Sbjct: 16 DEAESAPLPPSNSLGQEQLPSKNGGSHSIHNSQVPSLVSGADSPPSSPTGHNWEMNYQEA 75 Query: 427 IIFLGAQIVSKQIFTHPKD 445 I+L + + FTHPKD Sbjct: 76 AIYLQEGQNNDKFFTHPKD 94 >5MQC-B nrPDB Length = 231 Score = 29.4 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 36/87 (41%), Gaps = 5/87 (5%) Query: 322 DINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLIIEPEEEKSKREEEAKSVL---- 377 D+ + K ++I+I S F E L G + + +++ + + +L Sbjct: 75 DVPRNKQFMDSIMIPDDIISFPMFAEKLKGFSSLRATAVITVQFQTQPFQAGRVMLGSFP 134 Query: 378 -PAATKKKSKFMTNSTAFVPTIEYVQC 403 P + KF TN + + + +VQC Sbjct: 135 LPTLNPTRVKFATNHVSRLMLLNHVQC 161 >1ZXJ-A nrPDB Length = 218 Score = 28.6 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 3/60 (5%) Query: 53 YHSTNKDNKAELIKPIQNGEIIDIS---AFTQFLRLIFVSILSDRANKNQDAFEAELSNI 109 + +TN + A+L+KPIQ E+I++ A F+ IL+ + + A EL++I Sbjct: 25 HMATNLKSTAKLVKPIQYDEVIEVERIFADPAFIEQHRQRILASFKDAKESALYHELTHI 84 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.123 0.329 Lambda K H 0.267 0.0372 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,872,409 Number of Sequences: 36641 Number of extensions: 686147 Number of successful extensions: 2071 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 31 Number of HSP's that attempted gapping in prelim test: 1951 Number of HSP's gapped (non-prelim): 95 length of query: 467 length of database: 10,336,785 effective HSP length: 101 effective length of query: 366 effective length of database: 6,636,044 effective search space: 2428792104 effective search space used: 2428792104 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.9 bits)