BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q05098 (746 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5M9B-A nrPDB 1480 0.0 1FEP-A nrPDB 900 0.0 5FP2-A nrPDB 842 0.0 5FR8-A nrPDB 673 0.0 2HDF-A nrPDB 296 2e-80 1NQH-A nrPDB 76 6e-14 3FHH-A nrPDB 67 2e-11 6FOK-A nrPDB 59 7e-09 4EPA-A nrPDB 52 9e-07 5FP1-A nrPDB 52 9e-07 6E4V-A nrPDB 51 2e-06 1KMO-A nrPDB 49 7e-06 5FQ8-B nrPDB 48 2e-05 1FCP-A nrPDB 47 4e-05 5FOK-A nrPDB 46 6e-05 5NEC-A nrPDB 43 4e-04 6BPM-C nrPDB 41 0.002 3QLB-A nrPDB 39 0.006 2W78-A nrPDB 39 0.008 1XKH-A nrPDB 39 0.011 4ZGV-A nrPDB 37 0.024 6H7F-A nrPDB 34 0.26 3V8X-A nrPDB 33 0.34 4B7O-A nrPDB 33 0.49 4AIP-A nrPDB 32 1.3 4GN8-A nrPDB 31 2.1 4GNB-A nrPDB 30 4.9 4Y23-A nrPDB 29 5.9 5N9J-X nrPDB 29 7.5 3EFM-A nrPDB 29 9.7 >5M9B-A nrPDB Length = 724 Score = 1480 bits (3831), Expect = 0.0, Method: Compositional matrix adjust. Identities = 721/721 (100%), Positives = 721/721 (100%) Query: 26 AGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLT 85 AGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLT Sbjct: 4 AGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLT 63 Query: 86 GNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQ 145 GNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQ Sbjct: 64 GNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQ 123 Query: 146 VERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFG 205 VERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFG Sbjct: 124 VERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFG 183 Query: 206 LNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLS 265 LNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLS Sbjct: 184 LNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLS 243 Query: 266 WRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWD 325 WRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWD Sbjct: 244 WRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWD 303 Query: 326 FGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYE 385 FGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYE Sbjct: 304 FGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYE 363 Query: 386 QTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPG 445 QTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPG Sbjct: 364 QTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPG 423 Query: 446 TMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSR 505 TMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSR Sbjct: 424 TMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSR 483 Query: 506 GQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPV 565 GQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPV Sbjct: 484 GQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPV 543 Query: 566 DHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGD 625 DHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGD Sbjct: 544 DHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGD 603 Query: 626 VLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIA 685 VLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIA Sbjct: 604 VLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIA 663 Query: 686 GLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTAS 745 GLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTAS Sbjct: 664 GLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTAS 723 Query: 746 F 746 F Sbjct: 724 F 724 >1FEP-A nrPDB Length = 724 Score = 900 bits (2327), Expect = 0.0, Method: Compositional matrix adjust. Identities = 440/720 (61%), Positives = 547/720 (75%), Gaps = 17/720 (2%) Query: 38 EQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNR 97 + T+V TA E+ QAPGVS ITA++I K P + D+S+IIRTMPGVNLTGNS+SGQRGNNR Sbjct: 11 DDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNR 70 Query: 98 QIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAA 157 QIDIRGMGPENTLIL+DGKPVSSRNSVR GWRGERD+RGDT+WVP + +ERIEV+RGPAA Sbjct: 71 QIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAA 130 Query: 158 ARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSYR 217 ARYGNGAAGGVVNIITK+ E HG+ Y N P+HK EGA++R +F L GPL + S+R Sbjct: 131 ARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFR 190 Query: 218 VYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFE 277 +YGN+ KT +D WDIN GH+S R G A TLPAGREGV NKDI+G++ W P Q+LE E Sbjct: 191 LYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELE 250 Query: 278 AGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLA-YLQYE 336 AG+SRQGN+Y GDTQNTNS++Y + G ETNR+YR+ Y++T G WD G + + ++QYE Sbjct: 251 AGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYE 310 Query: 337 KTRNSRINEGLAGGTEGIFDPN-NAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLGSEWT 395 TRNSRI EGLAGGTEG F+ F L D+ H EVNLP+ QTLTLG+EW Sbjct: 311 HTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN 370 Query: 396 EQKLDDPSSNTQ---NTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPGTMLTPGL 452 +Q++ D SSNTQ T GG+I G++ +RS S A IFSLFAE+N+EL T++TPGL Sbjct: 371 QQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTPGL 430 Query: 453 RWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQ 512 R+DHH IVG+NWSP+LN+S L + TLK GIARAYKAP+LYQ NP+Y+LYS+GQGCY Sbjct: 431 RFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYAS 490 Query: 513 STSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGK 572 + CYL+GND LKAETS+NKE+G+E+ DG +AG+T+FRNDY+NKIE+G V + G Sbjct: 491 AGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVG- 549 Query: 573 GDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPR 632 +YQW+NVPKAVVEGLEG+L +P+++ + W+NN+TYML+S+NK TGD LS+ P Sbjct: 550 -----TDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPE 604 Query: 633 YTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIAGLGGTYR 692 YTLNS L WQA +DLS+Q T TWYGKQ+PKKY+Y G G ++SPY+I GL T+ Sbjct: 605 YTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWD 664 Query: 693 LSKNLSLGAGVDNLFDKRLFRAGNAQ------GVVGIDGAGAATYNEPGRTFYTSLTASF 746 ++KN+SL GVDNLFDKRL+RAGNAQ G I GAGA TYNEPGRT+Y S+ F Sbjct: 665 VTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF 724 >5FP2-A nrPDB Length = 725 Score = 842 bits (2175), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/720 (60%), Positives = 529/720 (73%), Gaps = 24/720 (3%) Query: 32 SVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSG 91 SV++LG++ V+ TA++E KQAPGVSIITAEDI KRPP NDLS+IIRTMPGVNLTGNSSSG Sbjct: 17 SVVQLGDEVVLGTAEQELKQAPGVSIITAEDIRKRPPVNDLSEIIRTMPGVNLTGNSSSG 76 Query: 92 QRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEV 151 QRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERD+RGD+NWVP ++VERIEV Sbjct: 77 QRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDTRGDSNWVPPEEVERIEV 136 Query: 152 IRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLT 211 +RGPAAARYG+GAAGGVVNIITK+ G+++V++N P+ +GA+ R +F L+GPLT Sbjct: 137 LRGPAAARYGSGAAGGVVNIITKRPTDRLRGSMTVFTNIPESSKDGATRRANFSLSGPLT 196 Query: 212 ENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPE 271 E LS+R YG+ KTDSDD DIN GH N + AGREGVRN+D+ G+LSW++TP+ Sbjct: 197 EALSFRAYGSANKTDSDDTDINLGHTVNPS-----RTVAGREGVRNRDLSGMLSWQVTPD 251 Query: 272 QTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQML--GHETNRMYRETYSVTHRGEWDFGSS 329 Q ++FEAGFSRQGNIY GDTQN N + + G ETNRMYRE Y++TH G W FG+S Sbjct: 252 QVVDFEAGFSRQGNIYAGDTQNNNGTANTQGLADDGAETNRMYRENYAITHNGTWSFGTS 311 Query: 330 LAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTLT 389 QY+ TRN+R+ EGLAG EG + + F + L + GE+NLPLH +EQ LT Sbjct: 312 RFVAQYDSTRNNRLEEGLAGSVEGQIGADRS-FSASKLENYRLSGELNLPLHALFEQVLT 370 Query: 390 LGSEWTEQKLDDPSSNTQNTEEGGSIPGL-AGKNRSSSSSARIFSLFAEDNIELMPGTML 448 +G+EW ++ L+DPSS Q S+PG A +RS S A I +L+ EDNIEL PGTML Sbjct: 371 VGAEWNKETLNDPSSLKQGFVGSDSLPGTPAAGSRSPKSKAEIRALYVEDNIELRPGTML 430 Query: 449 TPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQG 508 TPGLR D H G NWSPSLN S L E T+KAGIARA+KAPNLYQ NP+YLLY+RG G Sbjct: 431 TPGLRLDDHSDFGLNWSPSLNASQTLGEYFTVKAGIARAFKAPNLYQSNPNYLLYTRGNG 490 Query: 509 CYGQSTS--CYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVD 566 C Q++S CYL GN+ L AETSVNKELGIE+ DG VAGLTYFRNDYKNKI ++P+D Sbjct: 491 CPIQTSSGGCYLVGNENLDAETSVNKELGIEFRRDGWVAGLTYFRNDYKNKI---VAPLD 547 Query: 567 HASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGDV 626 G G N I QW N KAVVEGLEG L +PL + L WS NLTYMLQSK+K+TG+ Sbjct: 548 -VMGQTGTGNN--ILQWSNAKKAVVEGLEGNLLVPLHEDLSWSTNLTYMLQSKDKDTGNP 604 Query: 627 LSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIAG 686 LSV P YTLNS LDWQA++ LS Q T T YG+Q+P K+ + S ++ Y I G Sbjct: 605 LSVIPEYTLNSTLDWQASERLSTQLTSTIYGRQEPPKHGTSRNTPVVS-RKEVGTYGIWG 663 Query: 687 LGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTASF 746 + Y S+NLS+ GV NLFDKRL+R GN+ D AGAATYNEPGR +Y S+T SF Sbjct: 664 VSAGYTFSENLSVRGGVSNLFDKRLYRQGNS-----FD-AGAATYNEPGRAYYVSMTTSF 717 >5FR8-A nrPDB Length = 733 Score = 673 bits (1736), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/732 (49%), Positives = 480/732 (65%), Gaps = 47/732 (6%) Query: 39 QTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQ 98 +T+ TA+E+ KQ+ GVS+IT ED+ K P ND+S +R MPGVNLTGNS++GQRGNNRQ Sbjct: 25 ETIFVTAEEQVKQSLGVSVITKEDLEKLPVRNDISDYVRRMPGVNLTGNSATGQRGNNRQ 84 Query: 99 IDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAA 158 IDIRGMGPENTLILVDGKP++SRNSVRYGW+GERD+RGD+NWVPA+ +E IEV+RGPAAA Sbjct: 85 IDIRGMGPENTLILVDGKPINSRNSVRYGWKGERDTRGDSNWVPAEAIESIEVLRGPAAA 144 Query: 159 RYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTEN-LSYR 217 RYG+GAAGGVVNIITK+ ETHG++ Y++ P+ EG+S R+ F ++GPL ++ LSYR Sbjct: 145 RYGSGAAGGVVNIITKKVTNETHGSVEFYTSQPEDSKEGSSNRVGFNVSGPLIKDVLSYR 204 Query: 218 VYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFE 277 +YGN KT++DD DIN K G+ AGREGV+NKDI G L+W+ T +QT+ + Sbjct: 205 LYGNYNKTEADDVDIN---------KSIGSTAAGREGVKNKDISGRLAWQATDQQTVLLD 255 Query: 278 AGFSRQGNIYTGDTQ---NTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLAYLQ 334 S+QGNIY+GD+Q N ++ + Q++G ETN MYR++Y++TH G+W +G S Q Sbjct: 256 ISSSKQGNIYSGDSQLNANAEADAILSQLIGKETNTMYRDSYALTHEGDWSWGKSKLVAQ 315 Query: 335 YEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLGSEW 394 Y+KT N R+ EGLAG EG + N T+ L L +GE N+P Q LT+G+EW Sbjct: 316 YDKTHNKRLPEGLAGSVEGKIN-NLDDKATSRLETLRFNGEANIPFEYYLPQVLTVGTEW 374 Query: 395 TEQKLDDPSSNTQNTEEGGSIPG--LAGKNRSSSSSARIFSLFAEDNIELMPGTMLTPGL 452 E + D S TQ + GS G LA +RS S RI S + EDN+++ T + GL Sbjct: 375 VEDRFKDNVSTTQGKDSSGSGYGDQLAKGDRSKMES-RIASAYIEDNLKVTDSTDVVLGL 433 Query: 453 RWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQ 512 R+D H G NWSPSLN++ L + TLK G+A+AYKAPN+YQ YLL + G GC Sbjct: 434 RFDDHSKSGSNWSPSLNITQKLNDYFTLKGGVAKAYKAPNMYQNAEGYLLSTNGNGCPAN 493 Query: 513 STS-CYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGG 571 S C L+GN LK ETSVNKELGI++ D + A LT+FRNDYK+KI +G V G Sbjct: 494 IESRCLLQGNGDLKPETSVNKELGIQFQKDIVNASLTWFRNDYKDKIVAGTHVVGTVDGS 553 Query: 572 KGDYANAA-------IYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETG 624 + A I +WEN PKA+++G EG+L L D ++W+NN TYM+ SK+K+TG Sbjct: 554 STNANTGAVTNTKWNILRWENTPKALIQGFEGSLGLDFGD-IRWTNNFTYMMDSKDKQTG 612 Query: 625 DVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRV-----TGSANDQL 679 + LS+ P YT+NS+ D+ TD L + T YG+QK ++ + +R+ +G AN L Sbjct: 613 NPLSLVPIYTINSIFDYDITDQLDVNFVFTQYGRQKSRQ--FAENRLESGIGSGGANSAL 670 Query: 680 SP-----YAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEP 734 P Y+ AG+ Y+ S +S GV NLFDK++ R N+ + TYNEP Sbjct: 671 KPSTVKSYSTAGINVGYKFSDQISTRVGVSNLFDKQILRDSNSI---------SQTYNEP 721 Query: 735 GRTFYTSLTASF 746 GR +Y SL SF Sbjct: 722 GRAYYASLKYSF 733 >2HDF-A nrPDB Length = 639 Score = 296 bits (759), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 242/741 (32%), Positives = 366/741 (49%), Gaps = 128/741 (17%) Query: 32 SVIELGEQTVV--ATAQEETKQAPG-VSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNS 88 SV + GE VV ++ ++ K AP +S+IT ED+ ++P N L +++ +PGV LT Sbjct: 1 SVDDDGETMVVTASSVEQNLKDAPASISVITQEDLQRKPVQN-LKDVLKEVPGVQLT--- 56 Query: 89 SSGQRGNNRQ-IDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVE 147 G+NR+ + IRG+ TLILVDGK V+SRN+V R + D NW+P D +E Sbjct: 57 ---NEGDNRKGVSIRGLDSSYTLILVDGKRVNSRNAVF------RHNDFDLNWIPVDSIE 107 Query: 148 RIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLN 207 RIEV+RGP ++ YG+ A GGVVNIITK+ G + G ++V + +H+ G + F + Sbjct: 108 RIEVVRGPMSSLYGSDALGGVVNIITKKIGQKWSGTVTVDTTIQEHRDRGDTYNGQFFTS 167 Query: 208 GPLTEN-LSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSW 266 GPL + L + YG++AK + DD N T G P EG ++D + +W Sbjct: 168 GPLIDGVLGMKAYGSLAKREKDD-------PQNSTTTDTGETPR-IEGFSSRDGNVEFAW 219 Query: 267 RLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDF 326 TP Q +F AG Y D Q+ +S++ K NR+ R+ YSV+H G WD+ Sbjct: 220 --TPNQNHDFTAG-------YGFDRQDRDSDSLDK-------NRLERQNYSVSHNGRWDY 263 Query: 327 GSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQ 386 G+S EK N +P N+ T+ T G+ LPL Q Sbjct: 264 GTSELKYYGEKVENK--------------NPGNSSPITSESN--TVDGKYTLPL-TAINQ 306 Query: 387 TLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPGT 446 LT+G E K+ D + T GG+ SS +SA ++LF ED + Sbjct: 307 FLTVGGEMRHDKMSDAVNLT-----GGT---------SSKTSASQYALFVEDEWRIFEPL 352 Query: 447 MLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRG 506 LT G+R D H+ G++WSP L + T+ VT+K G A A+KAP+L QL+PD+ Sbjct: 353 ALTTGVRMDDHETYGEHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWT----S 408 Query: 507 QGCYGQSTSCYLRGNDGLKAETSVNKELGIEYS-----HDGLVAGLTYFRNDYKNKIESG 561 C G +C + G+ LK ETS + ELG+ Y +G+ + +T FRND K++I Sbjct: 409 NSCRG---ACKIVGSPDLKPETSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISIS 465 Query: 562 LSPVDHASGGKGDYA---------NAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNL 612 + +A+ G ++ ++ + NV KA ++G+E L +P D K S N Sbjct: 466 RTSDVNAAPGYQNFVGFETGANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINY 525 Query: 613 TY-----MLQSKNKETGDVLSVTPRYTLNSMLDWQ--ATDDLSLQATVTWYGKQKPKKYD 665 TY + +NK D+ P +T N LDW+ A +D S+ + + G+ K+ D Sbjct: 526 TYNDGRDVSNGENKPLSDL----PFHTANGTLDWKPLALEDWSMYMSGHYTGQ---KRAD 578 Query: 666 YHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDG 725 + G Y I G ++++K++ L AGV NL DK L R Sbjct: 579 SATAKTPGG-------YTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSR------------ 619 Query: 726 AGAATYNEPGRTFYTSLTASF 746 +YNE GR ++ ++ F Sbjct: 620 -DDYSYNEDGRRYFMAVDYRF 639 >1NQH-A nrPDB Length = 594 Score = 75.9 bits (185), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 69/203 (33%), Positives = 98/203 (48%), Gaps = 28/203 (13%) Query: 40 TVVATAQE-----ETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRG 94 T+V TA T AP +++T +DI R S ++ ++R +PGV++T N SGQ Sbjct: 7 TLVVTANRFEQPRSTVLAP-TTVVTRQDI-DRWQSTSVNDVLRRLPGVDITQNGGSGQLS 64 Query: 95 NNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRG 154 + I IRG + L+L+DG VR G S D + P V+R+E IRG Sbjct: 65 S---IFIRGTNASHVLVLIDG--------VRLNLAGVSGS-ADLSQFPIALVQRVEYIRG 112 Query: 155 PAAARYGNGAAGGVVNIIT--KQAGAETHGNL--SVYSNFPQHKAEGASERMSFGLNGPL 210 P +A YG+ A GGVVNIIT + G E + Y N+ + ++ L G Sbjct: 113 PRSAVYGSDAIGGVVNIITTRDEPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDY 172 Query: 211 TENLSYRV--YGNI---AKTDSD 228 Y V YGN A+TD+D Sbjct: 173 AHTHGYDVVAYGNTGTQAQTDND 195 Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust. Identities = 58/247 (23%), Positives = 87/247 (35%), Gaps = 65/247 (26%) Query: 474 LTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKE 533 E A +YKAPNL QL YG GN L E S E Sbjct: 379 FIEGYRFIASYGTSYKAPNLGQL-------------YG------FYGNPNLDPEKSKQWE 419 Query: 534 LGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEG 593 E GL AG+ + + Y+N + + DH ++ N KA ++G Sbjct: 420 GAFE----GLTAGVNWRISGYRNDVSDLIDYDDHT------------LKYYNEGKARIKG 463 Query: 594 LEGTLTL---PLADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQATDDLSLQ 650 +E T PL + + + ++N T L + + LDWQ D Sbjct: 464 VEATANFDTGPLTHTVSYD-----YVDARNAITDTPLLRRAKQQVKYQLDWQLY-DFDWG 517 Query: 651 ATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIAGLGGT--------YRLSKNLSLGAG 702 T + G + K Y + PY +GG Y ++ +L++ Sbjct: 518 ITYQYLGTRYDKDYSSY-------------PYQTVKMGGVSLWDLAVAYPVTSHLTVRGK 564 Query: 703 VDNLFDK 709 + NLFDK Sbjct: 565 IANLFDK 571 >3FHH-A nrPDB Length = 640 Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 135/583 (23%), Positives = 233/583 (39%), Gaps = 98/583 (16%) Query: 40 TVVATAQEETK-QAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQ 98 TV AT + +AP + + + + + ++R +PG+ L G R N + Sbjct: 5 TVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTG----RTNGQD 60 Query: 99 IDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAA 158 I++RG L+LVDG +R +G + ++ ++R+E++RGP+A Sbjct: 61 INMRGYDHRGVLVLVDG--------IR---QGTDTGHLNGTFLDPALIKRVEIVRGPSAL 109 Query: 159 RYGNGAAGGVVNIITKQA-GAETHGNLSVYSNFPQHKAEGASERMSFGLNGPL---TENL 214 YG+GA GGV++ T A G S + F G + S GL TENL Sbjct: 110 LYGSGALGGVISYDTVDAKDLLQEGQSSGFRVF----GTGGTGDHSLGLGASAFGRTENL 165 Query: 215 SYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTL 274 G +A + D D+ +SN G E + N G +W++ Q+L Sbjct: 166 D----GIVAWSSRDRGDL---RQSN------GETAPNDESINNMLAKG--TWQIDSAQSL 210 Query: 275 EFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHET-NRMYRETYSVTHRGEWDFGSSLAYL 333 + + Q ++ M+ T R + +Y + +G D+ ++ A + Sbjct: 211 SGLVRYYNNDAREPKNPQTVEASESSNPMVDRSTIQRDAQLSYKLAPQGN-DWLNADAKI 269 Query: 334 QYEKTRNSRINEGLAGG-----TEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTL 388 + + R + N G +G T+G N + + + HL L Sbjct: 270 YWSEVRINAQNTGSSGEYREQITKGARLENRSTLFADSFAS-----------HL-----L 313 Query: 389 TLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIEL--MPGT 446 T G E+ Q + S + + GG+ G SS + +D I L +P T Sbjct: 314 TYGGEYYRQ--EQGSHHHHHHHPGGATTGFPQAKIDFSSG------WLQDEITLRDLPIT 365 Query: 447 MLTPGLRWD--------HHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNP 498 +L G R+D + D+ D WS ++ T + L A+A++AP + ++ Sbjct: 366 LLG-GTRYDSYRGSSDGYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYN 424 Query: 499 DYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELG-------IEYSHDGLVAGLTYFR 551 D +S G+ + Y N L+ ET+ +E G + S+D L +YF Sbjct: 425 DSKHFS-----IGRFYTNYWVPNPNLRPETNETQEYGFGLRFDDLMLSNDALEFKASYFD 479 Query: 552 NDYKNKIESGLSPVDHASGGKGDY--ANAAIYQWENVPKAVVE 592 K+ I + VD A+ Y NA I+ W+ + K + Sbjct: 480 TKAKDYIS---TTVDFAAATTMSYNVPNAKIWGWDVMTKYTTD 519 >6FOK-A nrPDB Length = 723 Score = 58.9 bits (141), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 31/76 (40%), Positives = 42/76 (55%) Query: 671 VTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAAT 730 V G D+ + + + L G YR+++N+ L AGVDNLFDK N G G + T Sbjct: 648 VVGKDFDKSAGFGVFSLNGAYRVTRNVKLSAGVDNLFDKDYTEHLNKAGDAGFGFSANET 707 Query: 731 YNEPGRTFYTSLTASF 746 EPGRTF+T + SF Sbjct: 708 VPEPGRTFWTKVDFSF 723 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 61/236 (25%), Positives = 99/236 (41%), Gaps = 33/236 (13%) Query: 5 ALPAVPFLLLSSCLLANAVHAAGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIA 64 A A+ L LS L H+ Q +EL V AQ ++I+T Sbjct: 37 AFAALCGLALSPSALLAEEHS--QHQDHAVELAPSVVTGVAQSSP-----LTIVTNPKEP 89 Query: 65 KRP-PSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNS 123 ++P P++D + ++T+PG + N G+N +RGM IL +G + Sbjct: 90 RQPVPASDGADYLKTIPGFAVIRNG-----GSNGDPVLRGMFGSRLNILTNGGMM----- 139 Query: 124 VRYGWRGERDSRGD--TNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETH 181 G +R D T+++ + +++ VI+GP +G GA+ G I + E Sbjct: 140 -----LGACPNRMDAPTSYISPETYDKLTVIKGPQTVLWGPGASAGT---ILFEREPERF 191 Query: 182 GNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSY-RVYGNIAKTDSDDWDINAGH 236 G L N G++ R L+ L Y R GN A+ SDD++ AG+ Sbjct: 192 GELGSRVN--ASLLAGSNGRFDKVLDAAAGNRLGYLRFTGNHAQ--SDDYEDGAGN 243 >4EPA-A nrPDB Length = 655 Score = 52.0 bits (123), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 52/201 (25%), Positives = 89/201 (44%), Gaps = 46/201 (22%) Query: 31 GSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDL-----SQIIRTMPGVNL- 84 G + E T+V TA +++ ++ + +++ + P +D ++ R +PG+N+ Sbjct: 4 GQTSQQDESTLVVTASKQSSRSASANNVSST-VVSAPELSDAGVTASDKLPRVLPGLNIE 62 Query: 85 -TGN---SSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNW 140 +GN S+ RG + D P TL VDG P S N+++ Sbjct: 63 NSGNMLFSTISLRGVSSAQDF--YNPAVTL-YVDGVPQLSTNTIQ--------------- 104 Query: 141 VPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGA-- 198 V+ +E++RGP YG A GG++NI+T+Q + G + EG Sbjct: 105 -ALTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDSTPRGYI-----------EGGVS 152 Query: 199 ---SERMSFGLNGPLTENLSY 216 S R F L+GP+ + L Y Sbjct: 153 SRDSYRSKFNLSGPIQDGLLY 173 >5FP1-A nrPDB Length = 718 Score = 52.0 bits (123), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 157/726 (21%), Positives = 272/726 (37%), Gaps = 144/726 (19%) Query: 55 VSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVD 114 VS+I+ + I + L+ +RT+PG+ L G G +R IRG E+++ + Sbjct: 44 VSVISKQLIEDTKVTT-LADALRTVPGITL-GAGEGGNPNGDRPF-IRGYSSESSMYIDG 100 Query: 115 GKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITK 174 + +S+N + VE++EV +G A+A G G+ GG +N+I+K Sbjct: 101 IRNSTSQNREMFA------------------VEQVEVTKGSASAMGGAGSVGGSINMISK 142 Query: 175 ------------QAGAETHGNLSV-------------------------YSNFPQHKAEG 197 AG + + +++ SN ++K G Sbjct: 143 VAKKGDFLEGSVAAGTDNYQRITLDGNKDFGNGIAARVAVLGHQNEKAGQSNGAEYKRVG 202 Query: 198 ASERMSFGLNGPLTENLSYRVYGNIAKTDSDD--WDINAGHESNRTGKQAGTLPAGREGV 255 + ++FGL+ P LSY K DS WD + G GK A G Sbjct: 203 IAPSITFGLDTPTRATLSYYYLQTDDKPDSGIPYWDSSLGKAQ---GKPAEVKQGTYYGW 259 Query: 256 RNKDIDGL--------LSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHE 307 +++D L LT T+ A +++ N Y + + N K ++ H Sbjct: 260 KDRDFQKQENHIGTIKLEHDLTDNITITNTAMYAKSKNDYVWTNPDDSKGNVGKGLVWHR 319 Query: 308 TNRMYRETYSVTHR----GEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFY 363 N ++ + T + G++D G +L++ R N G E + G Y Sbjct: 320 LNSAITDSETFTDQLALTGKFDTG----FLKH------RFNVG----AEYSKQKTDKGGY 365 Query: 364 TATLRDLTAHGEVNLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNR 423 + A G V+ Y L + W L+ P+ + + P Sbjct: 366 NI----IDAKGNVSSTGF--YSDCSDLSTNWCTS-LNGPTQKPF-VDRLQARPDFDATVE 417 Query: 424 SSSSSARIFSLFAEDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHAL---TERVTL 480 S+S ++ DNIE+ P +L GLRWD + + + S ++ ++ VT Sbjct: 418 STS-------VYLLDNIEITPKWLLDLGLRWDKFEAEQNFLATSSAAAYTAKNNSDFVTY 470 Query: 481 KAGIARAYKAPNLYQLNPDYLLYSRGQGC---YGQSTSCYLRGNDGLKAETSVNKELGIE 537 +AGI +K + Y + G +G ++ N + E + E+G + Sbjct: 471 QAGI--TFKPTENGSIYTSYATSASPVGLNAGWGDNSETINANNQMIDPEEAQTFEIGTK 528 Query: 538 Y----SHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEG 593 + +H L A + FR + +N + P +A NV ++ V+G Sbjct: 529 WDFLDNHLNLTAAI--FRTEKQN-TRVQIDPTTYA----------------NVGESKVDG 569 Query: 594 LEGTLTLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQATDDLSLQATV 653 E L + D S TY+ K S + T S+ + ++ QA Sbjct: 570 FELGLNGEITDKWNISAGYTYLDSELTKNGKSCRS--GKCTDQSIYNGNQMPNVPKQAAT 627 Query: 654 TWYGKQKPKKYD-----YHGDRVTGS-ANDQLSP-YAIAGLGGTYRLSKNLSLGAGVDNL 706 W + + + D+V G AN + P Y Y ++KN+ L ++NL Sbjct: 628 LWTTYKVLPQLTVGAGAVYSDKVYGDVANTKWVPSYVRYDAMARYNVNKNVDLQLNINNL 687 Query: 707 FDKRLF 712 DKR F Sbjct: 688 SDKRYF 693 >6E4V-A nrPDB Length = 693 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 137/604 (22%), Positives = 225/604 (37%), Gaps = 95/604 (15%) Query: 146 VERIEVIRGPAAARYGNGAAGGVVNIITKQAGA-ETHGNLSVYSNFPQHKAEGASERMSF 204 ER+EV+RG G G +N++ K A + E G++S ER Sbjct: 119 FERVEVVRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSA------EYGSWNKERYVA 172 Query: 205 GLNGPLTEN--LSYRVYGNIAKTDS--DDWDINAGHESNRTGKQAGTLPAGREGVRNKDI 260 L PLTE+ + R+ G DS D ++ S G L G + I Sbjct: 173 DLQSPLTEDGKIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTTLSAGYEYQRI 232 Query: 261 D-GLLSWRLTPEQTLEFEA-GFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSV 318 D +W P + + + R + N N V L + ++ T + Sbjct: 233 DVNSPTWGGLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQQFADTWQATLNA 292 Query: 319 THRGEWDFGSSLAYLQYEKTRNSRIN--EGLAGGTEGIFDPN---------NAGFYTATL 367 TH E +F S + Y+ ++ +N +G+ G + P N+G Sbjct: 293 TH-SEVEFDSKMMYV------DAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDA 345 Query: 368 RDLTAHGEVNLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQ-NTEEGGSIPGLAG------ 420 DL A G L G + L G +++Q SS +E GS G Sbjct: 346 LDLFADGSYEL---FGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTD 402 Query: 421 ---KNRSSSSSARIFSLFAEDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTER 477 ++ + + + SL+A + L L G R+ + + D + S+ +H Sbjct: 403 WSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRV--DTLTYSMEKNH----- 455 Query: 478 VTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDG------LKAETSVN 531 T AG+ ++ +N ++ Y TS + ND L T N Sbjct: 456 TTPYAGL--------VFDINDNW-------STYASYTSIFQPQNDRDSSGKYLAPITGNN 500 Query: 532 KELGI--EYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKA 589 ELG+ ++ + L L FR + N +S +P+ G G+ A A V Sbjct: 501 YELGLKSDWMNSRLTTTLAIFRIEQDNVAQSTGTPI---PGSNGETAYKA------VDGT 551 Query: 590 VVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQ--ATDDL 647 V +G+E L + D + + T + N E V PR T+ ++ +L Sbjct: 552 VSKGVEFELNGAITDNWQLTFGATRYIAEDN-EGNAVNPNLPRTTVKMFTSYRLPVMPEL 610 Query: 648 SLQATVTWYGKQKPKKYDYHGDRVT--GSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDN 705 ++ V W + + D VT G+ + YA+ L Y+++KN SL V+N Sbjct: 611 TVGGGVNWQNR-------VYTDTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNN 663 Query: 706 LFDK 709 LFDK Sbjct: 664 LFDK 667 >1KMO-A nrPDB Length = 774 Score = 49.3 bits (116), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 12/121 (9%) Query: 57 IITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPE---NTLILV 113 +I ED AK + + +++ +PGV+ N+ +G IRG+ P + +L+ Sbjct: 139 VIRREDFAKTGATT-MREVLNRIPGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTVLM 197 Query: 114 DGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIIT 173 DG PV YG + V ++ I+V+RG A RYG + GGVVN +T Sbjct: 198 DGIPVPF---APYG-----QPQLSLAPVSLGNMDAIDVVRGGGAVRYGPQSVGGVVNFVT 249 Query: 174 K 174 + Sbjct: 250 R 250 >5FQ8-B nrPDB Length = 984 Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 47/155 (30%), Positives = 75/155 (48%), Gaps = 14/155 (9%) Query: 35 ELGEQTVVATAQEETKQAPGVSIITA--EDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQ 92 ++ E V A + +++A G + + E IA+ S+ +S + + GV ++ S+S Sbjct: 22 QIDEVVVTAMGIKRSEKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQIS--STSSD 79 Query: 93 RGNNRQIDIRGM----GPENTLILVDGKPVSSRNSVRY---GWRGERDSRGDTNWVPADQ 145 G + + IRG+ G L +VDG P++ NS Y G D N + D Sbjct: 80 PGASNSVIIRGVSSLSGTNQPLYVVDGVPLN--NSTVYSTDGLNSGYDFGNGANAINPDD 137 Query: 146 VERIEVIRGPAA-ARYGNGAAGGVVNIITKQAGAE 179 V + +++G AA A YG+ AA GVV I TK E Sbjct: 138 VANMTILKGAAATALYGSRAANGVVMITTKSGRKE 172 >1FCP-A nrPDB Length = 705 Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 21/128 (16%) Query: 55 VSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQID---IRGMGPENTLI 111 +S++TAE++A P + + + + PGV S G RG + D IRG E Sbjct: 32 ISVVTAEEMALHQPKS-VKEALSYTPGV------SVGTRGASNTYDHLIIRGFAAEG--- 81 Query: 112 LVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNI 171 S+N+ G + + + D P +ER E++RGP + YG + GG++N+ Sbjct: 82 -------QSQNNYLNGLKLQGNFYNDAVIDPY-MLERAEIMRGPVSVLYGKSSPGGLLNM 133 Query: 172 ITKQAGAE 179 ++K+ E Sbjct: 134 VSKRPTTE 141 >5FOK-A nrPDB Length = 730 Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 48/211 (22%), Positives = 83/211 (39%), Gaps = 44/211 (20%) Query: 33 VIELGEQTVVATAQEETK----------------QAPGVSIITAEDIAKRPPSNDLSQII 76 V+ L T+V Q+ET P + + + K + L+ + Sbjct: 14 VLSLDAATIVGEQQDETTYNVDRSASKKYTAPLLDTPKTVTVIPQQVIKDTGALTLADAL 73 Query: 77 RTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRG 136 RT PG+ G G +R IRG E+ L + V+S+ + Sbjct: 74 RTTPGITF-GAGEGGNPAGDRPF-IRGFNAESDTFLDGMRDVASQTREVF---------- 121 Query: 137 DTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAE 196 VE+IEV +GP +A G G+ GG +N+I+K A + + Q Sbjct: 122 --------NVEQIEVSKGPGSAYTGAGSTGGSLNLISKTAKQDNFTDAGFTWGSDQ---- 169 Query: 197 GASERMSFGLNGPLTENLSYRVYGNIAKTDS 227 + R + +N + +N ++R+ N+ K D+ Sbjct: 170 --TRRTTLDVNRMIGDNAAFRL--NLMKHDA 196 Score = 34.7 bits (78), Expect = 0.17, Method: Compositional matrix adjust. Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 34/201 (16%) Query: 520 GNDGLKAETSVNKELGIEYSH--DGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYAN 577 GN+GL E + N ELG +++ D L FR D N A D + Sbjct: 520 GNNGLDPERNRNLELGTKWAFFDDALSLNAALFRTDKTN-----------ARVASPDVST 568 Query: 578 AAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKET--GDVLSVTPRYTL 635 + E + V G G LT + K TY+ K T D + P+ Sbjct: 569 LQVLDGEQRVQGVELGFNGKLT----EKWKVFGGYTYLDSEIRKSTVKSDEGNKMPQTAQ 624 Query: 636 NSMLDWQATD---DLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSP-YAIAGLGGTY 691 N+ W D + ++ T+ KQ +G+ +AN P Y +Y Sbjct: 625 NNFTLWTTYDLLQNFTIGGGTTYVDKQ-------YGN----TANSTYIPSYWRYDAMASY 673 Query: 692 RLSKNLSLGAGVDNLFDKRLF 712 ++SKN+ L V NL DKR F Sbjct: 674 KVSKNVDLQLNVQNLTDKRYF 694 >5NEC-A nrPDB Length = 741 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 45/176 (25%), Positives = 72/176 (40%), Gaps = 39/176 (22%) Query: 22 AVHAAGQ---GDGSVIELGEQTVVATAQEETK----------------QAPGVSIITAED 62 A++ AGQ V+ L T+V Q+ET P + + Sbjct: 1 AMNEAGQKKTDKDRVLSLDAATIVGEQQDETTYNVDRSASKKYTAPLLDTPRSVTVVPKQ 60 Query: 63 IAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRN 122 + K + L +RT+PG+ G G +R IRG ++ + Sbjct: 61 VIKDTAAVSLQDALRTVPGITF-GAGEGGNPTGDRPF-IRGFDAQSDTYV---------- 108 Query: 123 SVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGA 178 G RD+ T + +E+IEV +GP +A G G+AGG +N+++KQA A Sbjct: 109 ------DGVRDTGAQTREIF--NLEQIEVSKGPNSAFGGRGSAGGSLNLVSKQAKA 156 >6BPM-C nrPDB Length = 727 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 34/121 (28%), Positives = 58/121 (47%), Gaps = 24/121 (19%) Query: 58 ITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQID---IRGMGPENTLILVD 114 + +E + K + +L+ ++ +PGV G +G+ GN+ D +RG N+ I +D Sbjct: 44 VISEQVIKDQGATNLTDALKNVPGV---GAFFAGENGNSTTGDAIYMRGADTSNS-IYID 99 Query: 115 GKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITK 174 G +R RD+ E++EVI+GP+ YG A G +N+I+K Sbjct: 100 G--------IRDIGSVSRDTF---------NTEQVEVIKGPSGTDYGRSAPTGSINMISK 142 Query: 175 Q 175 Q Sbjct: 143 Q 143 Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust. Identities = 83/380 (21%), Positives = 137/380 (36%), Gaps = 60/380 (15%) Query: 374 GEVNLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFS 433 G + + G E T + + + P+ N + + GL +++ F+ Sbjct: 355 GSIGHDVSTGVEFTRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFA 414 Query: 434 LFAEDNIELMPGTMLTPGLRWDHHDIVGDNWSPS-------------LNLSHALTERVTL 480 ++A D +++ L G+R D++ D+ + + +T T Sbjct: 415 IYAFDTLQITRDFELNGGIRLDNYHTEYDSATACGGSGRGAITCPTGVAKGSPVTTVDTA 474 Query: 481 KAGIARAYKAPNLYQLNPD---YLLYSRGQGCYG-------QSTSCYLRGNDGLKAETSV 530 K+G +KA LY L + Y+ Y+ Q G QS S K + + Sbjct: 475 KSGNLMNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKAN 534 Query: 531 NKELGIEYS--HDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPK 588 E+G ++ L+ FR D +N++E G Y+ K Sbjct: 535 TSEIGTKWQVLDKRLLLTAALFRTDIENEVEQN---------DDGTYSQYG--------K 577 Query: 589 AVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETG-DV-------LSVTPRYTLNSMLD 640 VEG E ++ + W Y Q + G DV L TP + Sbjct: 578 KRVEGYEISVAGNITPA--WQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQ 635 Query: 641 WQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGS-ANDQLSPYAIAGLGGTYRLSKNLSL 699 +QATDD+S+ A + G D G+ A + A A LG YR+++NL Sbjct: 636 YQATDDISVGAGARYIGSMHKGS-----DGAVGTPAFTEGYWVADAKLG--YRVNRNLDF 688 Query: 700 GAGVDNLFDKRLFRAGNAQG 719 V NLFD + N G Sbjct: 689 QLNVYNLFDTDYVASINKSG 708 >3QLB-A nrPDB Length = 748 Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 18/87 (20%) Query: 141 VPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAE---G 197 V A +ERI+V++GPA+ +G + GGVVN I+K+ + P H+ + G Sbjct: 172 VEAYGLERIDVLKGPASVLFGQNSPGGVVNQISKRP-----------LDKPFHEVQIQGG 220 Query: 198 ASERM--SFGLNGPLTE--NLSYRVYG 220 + +R F +GPL + YR+ G Sbjct: 221 SFDRAQGQFDFSGPLDDEGQFLYRLVG 247 >2W78-A nrPDB Length = 772 Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust. Identities = 55/230 (23%), Positives = 85/230 (36%), Gaps = 25/230 (10%) Query: 493 LYQLNPDYLLYSRGQGCYGQSTSCYL-RGNDGLKAETSVNKELGI--EYSHDGLVAGLTY 549 +Y LN Y +Y+ + S Y N L+ + N E+GI EY L L Y Sbjct: 533 VYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAY 592 Query: 550 FRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWS 609 F +N+ E + YA I KA +G E ++ LA G + Sbjct: 593 FEIHEENRAEEDALYNSKPTNPAITYAYKGI-------KAKTKGYEAEISGELAPGWQVQ 645 Query: 610 NNLTYMLQSKNK-------ETGDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPK 662 T+ + + E D LS+ Y LD L++ W GK Sbjct: 646 AGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALD-----KLTVGGGARWQGKSWQM 700 Query: 663 KYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLF 712 Y+ R + + Y + L Y+++ LS V+N+FDK + Sbjct: 701 VYNNPRSRWEKFSQED---YWLVDLMARYQITDKLSASVNVNNVFDKTYY 747 Score = 34.3 bits (77), Expect = 0.20, Method: Compositional matrix adjust. Identities = 40/154 (25%), Positives = 69/154 (44%), Gaps = 34/154 (22%) Query: 70 NDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWR 129 N++ ++R PG+ ++ + R N RG N DG P ++RN V Y Sbjct: 140 NNIDDVMRHTPGITVSAYDT--DRNNYYA---RGFSINN--FQYDGIPSTARN-VGY--- 188 Query: 130 GERDSRGDTNWVPADQV--ERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSV- 186 S G+T +D +R+EV++G G G+ G +N+I K+ E G++ + Sbjct: 189 ----SAGNT---LSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELG 241 Query: 187 ---YSNFPQHKAEGASERMSFGLNGPLTENLSYR 217 + N+ R ++GPLTE+ + R Sbjct: 242 AGSWDNY----------RSELDVSGPLTESGNVR 265 >1XKH-A nrPDB Length = 687 Score = 38.5 bits (88), Expect = 0.011, Method: Compositional matrix adjust. Identities = 55/230 (23%), Positives = 85/230 (36%), Gaps = 25/230 (10%) Query: 493 LYQLNPDYLLYSRGQGCYGQSTSCYL-RGNDGLKAETSVNKELGI--EYSHDGLVAGLTY 549 +Y LN Y +Y+ + S Y N L+ + N E+GI EY L L Y Sbjct: 448 VYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAY 507 Query: 550 FRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWS 609 F +N+ E + YA I KA +G E ++ LA G + Sbjct: 508 FEIHEENRAEEDALYNSKPTNPAITYAYKGI-------KAKTKGYEAEISGELAPGWQVQ 560 Query: 610 NNLTYMLQSKNK-------ETGDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPK 662 T+ + + E D LS+ Y LD L++ W GK Sbjct: 561 AGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALD-----KLTVGGGARWQGKSWQM 615 Query: 663 KYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLF 712 Y+ R + + Y + L Y+++ LS V+N+FDK + Sbjct: 616 VYNNPRSRWEKFSQED---YWLVDLMARYQITDKLSASVNVNNVFDKTYY 662 Score = 35.0 bits (79), Expect = 0.13, Method: Compositional matrix adjust. Identities = 44/183 (24%), Positives = 81/183 (44%), Gaps = 37/183 (20%) Query: 36 LGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGN 95 + T + ET Q+ ++++T +++ N++ ++R PG+ ++ + R N Sbjct: 24 IATATRLVLTPRETPQS--ITVVTRQNMDDFG-LNNIDDVMRHTPGITVSAYDT--DRNN 78 Query: 96 NRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQV--ERIEVIR 153 RG N DG P ++RN V Y S G+T +D +R+EV++ Sbjct: 79 YYA---RGFSINN--FQYDGIPSTARN-VGY-------SAGNT---LSDMAIYDRVEVLK 122 Query: 154 GPAAARYGNGAAGGVVNIITKQAGAETHGNLSV----YSNFPQHKAEGASERMSFGLNGP 209 G G G+ G +N+I K+ E G++ + + N+ R ++GP Sbjct: 123 GATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNY----------RSELDVSGP 172 Query: 210 LTE 212 LTE Sbjct: 173 LTE 175 >4ZGV-A nrPDB Length = 868 Score = 37.4 bits (85), Expect = 0.024, Method: Compositional matrix adjust. Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 19/142 (13%) Query: 49 TKQAPGVSIITAEDIAKRPPSN-DLSQIIRTMPGVNLTGNSSSGQRGNN---RQIDIRGM 104 T Q+ G+ II AE I K P N ++++++ P V + +SS + G Sbjct: 63 TSQSMGMQIINAEQIKKMPTGNGSVTELLKNNPNVQFSNTASSSNIPGELAPENVSFHGE 122 Query: 105 GPENTLILVDGKPVSSRNSVRYGWRGERDSRGD-------------TNWVPADQVERIEV 151 N +VDG ++ + GE + + D + W+ ++ +E +EV Sbjct: 123 KFYNNNFMVDGLSNNNNINPGAN-NGELNQQPDGYSPADLPAGGPQSFWINSELIESLEV 181 Query: 152 IRGPAAARYGNGAAGGVVNIIT 173 +A+YG+ GGVV+ T Sbjct: 182 FDSNISAKYGD-FTGGVVDAKT 202 >6H7F-A nrPDB Length = 706 Score = 33.9 bits (76), Expect = 0.26, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 3/41 (7%) Query: 148 RIEVIRGPAAARYG---NGAAGGVVNIITKQAGAETHGNLS 185 R+EV++GP+A G G+ GG VN++TK A E L+ Sbjct: 137 RVEVLKGPSALLNGMPPAGSVGGTVNLVTKYAADEPFARLT 177 >3V8X-A nrPDB Length = 904 Score = 33.5 bits (75), Expect = 0.34, Method: Compositional matrix adjust. Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 6/122 (4%) Query: 57 IITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGK 116 ++ + D + ++ + R PG+ + RG + IRGM + VDG Sbjct: 50 LVKSSDTLSKEQVLNIRDLTRYDPGIAVVEQG----RGASSGYSIRGMDKNRVSLTVDGV 105 Query: 117 PVSSRNSVRYGWRGERD--SRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITK 174 + + G R S G N + + V+ +E+ +G + G+GA G V TK Sbjct: 106 SQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTK 165 Query: 175 QA 176 A Sbjct: 166 TA 167 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 10/85 (11%) Query: 670 RVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGA--- 726 R T + + P+ I + G Y + K+ +L AGV NL + R N + G GA Sbjct: 822 RNTKATARRTRPWYIVDVSGYYTVKKHFTLRAGVYNLLNYRYVTWENVRQTAG--GAVNQ 879 Query: 727 --GAATYNE---PGRTFYTSLTASF 746 YN PGR + SL F Sbjct: 880 HKNVGVYNRYAAPGRNYTFSLEYKF 904 >4B7O-A nrPDB Length = 745 Score = 33.1 bits (74), Expect = 0.49, Method: Compositional matrix adjust. Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 20/119 (16%) Query: 440 IELMPGTMLTPGLRWDH-----HD---IVGDNWSPSLNLSHALTERVTLKAGIARAYKAP 491 I + G LT GLR+D HD + N +PS + E + + A ++P Sbjct: 452 IHELDGFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSSSHNYASRSP 511 Query: 492 NLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYF 550 LY D L +G + DG KAE + N E+G Y+ A +YF Sbjct: 512 RLY----DALQTHGKRGIISIA--------DGTKAERARNTEIGFNYNDGTFAANGSYF 558 >4AIP-A nrPDB Length = 742 Score = 31.6 bits (70), Expect = 1.3, Method: Compositional matrix adjust. Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 20/111 (18%) Query: 448 LTPGLRWDH-----HD---IVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPD 499 LT GLR+D HD + N +PS + E + A A ++P LY D Sbjct: 457 LTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSASHNYASRSPRLY----D 512 Query: 500 YLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYF 550 L +G + DG KAE + N E+G Y+ A +YF Sbjct: 513 ALQTHGKRGIISIA--------DGTKAERARNTEIGFNYNDGTFAANGSYF 555 >4GN8-A nrPDB Length = 299 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 3/70 (4%) Query: 173 TKQAGAETHGNLSVYSNFPQHKAEGASER--MSFGLNGPLTENLSYRVYGNIAKTDSDDW 230 T A E H S+YS FP H + ++ +S GL+ L + Y + D+ D+ Sbjct: 122 TAPAVLERHQG-SLYSLFPDHSVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYTVDAFDY 180 Query: 231 DINAGHESNR 240 D+ G SNR Sbjct: 181 DLQTGQISNR 190 >4GNB-A nrPDB Length = 299 Score = 29.6 bits (65), Expect = 4.9, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 3/70 (4%) Query: 173 TKQAGAETHGNLSVYSNFPQHKAEGASER--MSFGLNGPLTENLSYRVYGNIAKTDSDDW 230 T A E H ++YS FP H + ++ +S GL+ L + Y + D+ D+ Sbjct: 122 TAPAVLERHQG-ALYSLFPDHHVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYSVDAFDY 180 Query: 231 DINAGHESNR 240 D+ G SNR Sbjct: 181 DLQTGQISNR 190 >4Y23-A nrPDB Length = 585 Score = 29.3 bits (64), Expect = 5.9, Method: Compositional matrix adjust. Identities = 32/114 (28%), Positives = 44/114 (38%), Gaps = 11/114 (9%) Query: 1 MSSRALPAVPFLLLSSCLLANAVHAAGQ---GDGSVIELGEQTVVATAQEETKQAPGVSI 57 M A V F L C + A G GDG + +G+ +VATA P S Sbjct: 1 MRRLAFLVVAFCLAVGCFFSPVSKAEGVMSGGDGDKVAVGKDGMVATAH------PLASK 54 Query: 58 ITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLI 111 I AE + K N + I +N+T SG G + G E ++I Sbjct: 55 IGAEVLKKG--GNAIDAAIAIQYALNVTEPMMSGIGGGGFMMVYDGETKETSII 106 >5N9J-X nrPDB Length = 210 Score = 28.9 bits (63), Expect = 7.5, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 4/77 (5%) Query: 497 NPDYLLYSRGQGCYGQSTSCYLRGNDGLK----AETSVNKELGIEYSHDGLVAGLTYFRN 552 N + +Y G + C +R + K + T +++G E+SH+ ++ GL YF Sbjct: 78 NTQWSMYLEGNSEPKREDKCGIRPVNRAKLTNGSVTEFVEKMGYEFSHEYIIQGLEYFFF 137 Query: 553 DYKNKIESGLSPVDHAS 569 D +I L P S Sbjct: 138 DTTVRIYQTLIPSQQRS 154 >3EFM-A nrPDB Length = 707 Score = 28.9 bits (63), Expect = 9.7, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 682 YAIAGLGGTYRLSKNLSLGAGVDNLFDKRLF 712 YA+ L + +K LS V+NLFDK+ + Sbjct: 652 YALVSLMARFDFNKKLSATLNVNNLFDKKYY 682 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5M9B-A nrPDB 930 0.0 1FEP-A nrPDB 821 0.0 5FP2-A nrPDB 789 0.0 5FR8-A nrPDB 714 0.0 2HDF-A nrPDB 542 e-154 5FP1-A nrPDB 430 e-120 6E4V-A nrPDB 408 e-114 3FHH-A nrPDB 354 8e-98 6FOK-A nrPDB 288 9e-78 5FOK-A nrPDB 249 3e-66 5NEC-A nrPDB 249 5e-66 1NQH-A nrPDB 194 2e-49 1KMO-A nrPDB 165 9e-41 4EPA-A nrPDB 160 3e-39 1FCP-A nrPDB 132 5e-31 5FQ8-B nrPDB 100 2e-21 Sequences not found previously or not previously below threshold: 2W78-A nrPDB 175 6e-44 1XKH-A nrPDB 172 5e-43 3EFM-A nrPDB 172 7e-43 6BPM-C nrPDB 155 6e-38 1XKW-A nrPDB 141 1e-33 3CSL-A nrPDB 112 9e-25 3QLB-A nrPDB 109 4e-24 4AIP-A nrPDB 95 1e-19 6H7F-A nrPDB 90 5e-18 4B7O-A nrPDB 87 3e-17 4RDT-A nrPDB 84 2e-16 3V8X-A nrPDB 81 1e-15 4ZGV-A nrPDB 54 3e-07 1W99-A nrPDB 33 0.48 3W1J-A nrPDB 31 1.2 3W1H-A nrPDB 31 1.2 1KFW-A nrPDB 30 4.1 >5M9B-A nrPDB Length = 724 Score = 930 bits (2404), Expect = 0.0, Method: Composition-based stats. Identities = 721/721 (100%), Positives = 721/721 (100%) Query: 26 AGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLT 85 AGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLT Sbjct: 4 AGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLT 63 Query: 86 GNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQ 145 GNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQ Sbjct: 64 GNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQ 123 Query: 146 VERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFG 205 VERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFG Sbjct: 124 VERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFG 183 Query: 206 LNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLS 265 LNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLS Sbjct: 184 LNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLS 243 Query: 266 WRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWD 325 WRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWD Sbjct: 244 WRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWD 303 Query: 326 FGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYE 385 FGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYE Sbjct: 304 FGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYE 363 Query: 386 QTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPG 445 QTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPG Sbjct: 364 QTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPG 423 Query: 446 TMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSR 505 TMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSR Sbjct: 424 TMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSR 483 Query: 506 GQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPV 565 GQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPV Sbjct: 484 GQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPV 543 Query: 566 DHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGD 625 DHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGD Sbjct: 544 DHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGD 603 Query: 626 VLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIA 685 VLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIA Sbjct: 604 VLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIA 663 Query: 686 GLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTAS 745 GLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTAS Sbjct: 664 GLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTAS 723 Query: 746 F 746 F Sbjct: 724 F 724 >1FEP-A nrPDB Length = 724 Score = 821 bits (2120), Expect = 0.0, Method: Composition-based stats. Identities = 440/720 (61%), Positives = 547/720 (75%), Gaps = 17/720 (2%) Query: 38 EQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNR 97 + T+V TA E+ QAPGVS ITA++I K P + D+S+IIRTMPGVNLTGNS+SGQRGNNR Sbjct: 11 DDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNR 70 Query: 98 QIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAA 157 QIDIRGMGPENTLIL+DGKPVSSRNSVR GWRGERD+RGDT+WVP + +ERIEV+RGPAA Sbjct: 71 QIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAA 130 Query: 158 ARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSYR 217 ARYGNGAAGGVVNIITK+ E HG+ Y N P+HK EGA++R +F L GPL + S+R Sbjct: 131 ARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFR 190 Query: 218 VYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFE 277 +YGN+ KT +D WDIN GH+S R G A TLPAGREGV NKDI+G++ W P Q+LE E Sbjct: 191 LYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELE 250 Query: 278 AGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLA-YLQYE 336 AG+SRQGN+Y GDTQNTNS++Y + G ETNR+YR+ Y++T G WD G + + ++QYE Sbjct: 251 AGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYE 310 Query: 337 KTRNSRINEGLAGGTEGIFDPN-NAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLGSEWT 395 TRNSRI EGLAGGTEG F+ F L D+ H EVNLP+ QTLTLG+EW Sbjct: 311 HTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN 370 Query: 396 EQKLDDPSSNTQ---NTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPGTMLTPGL 452 +Q++ D SSNTQ T GG+I G++ +RS S A IFSLFAE+N+EL T++TPGL Sbjct: 371 QQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTPGL 430 Query: 453 RWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQ 512 R+DHH IVG+NWSP+LN+S L + TLK GIARAYKAP+LYQ NP+Y+LYS+GQGCY Sbjct: 431 RFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYAS 490 Query: 513 STSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGK 572 + CYL+GND LKAETS+NKE+G+E+ DG +AG+T+FRNDY+NKIE+G V + G Sbjct: 491 AGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGT 550 Query: 573 GDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPR 632 +YQW+NVPKAVVEGLEG+L +P+++ + W+NN+TYML+S+NK TGD LS+ P Sbjct: 551 ------DLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPE 604 Query: 633 YTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIAGLGGTYR 692 YTLNS L WQA +DLS+Q T TWYGKQ+PKKY+Y G G ++SPY+I GL T+ Sbjct: 605 YTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWD 664 Query: 693 LSKNLSLGAGVDNLFDKRLFRAGNAQ------GVVGIDGAGAATYNEPGRTFYTSLTASF 746 ++KN+SL GVDNLFDKRL+RAGNAQ G I GAGA TYNEPGRT+Y S+ F Sbjct: 665 VTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF 724 >5FP2-A nrPDB Length = 725 Score = 789 bits (2036), Expect = 0.0, Method: Composition-based stats. Identities = 436/721 (60%), Positives = 524/721 (72%), Gaps = 24/721 (3%) Query: 31 GSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSS 90 SV++LG++ V+ TA++E KQAPGVSIITAEDI KRPP NDLS+IIRTMPGVNLTGNSSS Sbjct: 16 ESVVQLGDEVVLGTAEQELKQAPGVSIITAEDIRKRPPVNDLSEIIRTMPGVNLTGNSSS 75 Query: 91 GQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIE 150 GQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERD+RGD+NWVP ++VERIE Sbjct: 76 GQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDTRGDSNWVPPEEVERIE 135 Query: 151 VIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPL 210 V+RGPAAARYG+GAAGGVVNIITK+ G+++V++N P+ +GA+ R +F L+GPL Sbjct: 136 VLRGPAAARYGSGAAGGVVNIITKRPTDRLRGSMTVFTNIPESSKDGATRRANFSLSGPL 195 Query: 211 TENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTP 270 TE LS+R YG+ KTDSDD DIN GH N + AGREGVRN+D+ G+LSW++TP Sbjct: 196 TEALSFRAYGSANKTDSDDTDINLGHTVNPS-----RTVAGREGVRNRDLSGMLSWQVTP 250 Query: 271 EQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQML--GHETNRMYRETYSVTHRGEWDFGS 328 +Q ++FEAGFSRQGNIY GDTQN N + + G ETNRMYRE Y++TH G W FG+ Sbjct: 251 DQVVDFEAGFSRQGNIYAGDTQNNNGTANTQGLADDGAETNRMYRENYAITHNGTWSFGT 310 Query: 329 SLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTL 388 S QY+ TRN+R+ EGLAG EG + + F + L + GE+NLPLH +EQ L Sbjct: 311 SRFVAQYDSTRNNRLEEGLAGSVEGQIGADRS-FSASKLENYRLSGELNLPLHALFEQVL 369 Query: 389 TLGSEWTEQKLDDPSSNTQNTEEGGSIPGLA-GKNRSSSSSARIFSLFAEDNIELMPGTM 447 T+G+EW ++ L+DPSS Q S+PG +RS S A I +L+ EDNIEL PGTM Sbjct: 370 TVGAEWNKETLNDPSSLKQGFVGSDSLPGTPAAGSRSPKSKAEIRALYVEDNIELRPGTM 429 Query: 448 LTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQ 507 LTPGLR D H G NWSPSLN S L E T+KAGIARA+KAPNLYQ NP+YLLY+RG Sbjct: 430 LTPGLRLDDHSDFGLNWSPSLNASQTLGEYFTVKAGIARAFKAPNLYQSNPNYLLYTRGN 489 Query: 508 GCYGQSTS--CYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPV 565 GC Q++S CYL GN+ L AETSVNKELGIE+ DG VAGLTYFRNDYKNKI + L Sbjct: 490 GCPIQTSSGGCYLVGNENLDAETSVNKELGIEFRRDGWVAGLTYFRNDYKNKIVAPLD-- 547 Query: 566 DHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGD 625 G G N I QW N KAVVEGLEG L +PL + L WS NLTYMLQSK+K+TG+ Sbjct: 548 --VMGQTGTGNN--ILQWSNAKKAVVEGLEGNLLVPLHEDLSWSTNLTYMLQSKDKDTGN 603 Query: 626 VLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIA 685 LSV P YTLNS LDWQA++ LS Q T T YG+Q+P K+ + S ++ Y I Sbjct: 604 PLSVIPEYTLNSTLDWQASERLSTQLTSTIYGRQEPPKHGTSRNTPVVS-RKEVGTYGIW 662 Query: 686 GLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTAS 745 G+ Y S+NLS+ GV NLFDKRL+R GN+ AGAATYNEPGR +Y S+T S Sbjct: 663 GVSAGYTFSENLSVRGGVSNLFDKRLYRQGNSFD------AGAATYNEPGRAYYVSMTTS 716 Query: 746 F 746 F Sbjct: 717 F 717 >5FR8-A nrPDB Length = 733 Score = 714 bits (1841), Expect = 0.0, Method: Composition-based stats. Identities = 359/732 (49%), Positives = 480/732 (65%), Gaps = 47/732 (6%) Query: 39 QTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQ 98 +T+ TA+E+ KQ+ GVS+IT ED+ K P ND+S +R MPGVNLTGNS++GQRGNNRQ Sbjct: 25 ETIFVTAEEQVKQSLGVSVITKEDLEKLPVRNDISDYVRRMPGVNLTGNSATGQRGNNRQ 84 Query: 99 IDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAA 158 IDIRGMGPENTLILVDGKP++SRNSVRYGW+GERD+RGD+NWVPA+ +E IEV+RGPAAA Sbjct: 85 IDIRGMGPENTLILVDGKPINSRNSVRYGWKGERDTRGDSNWVPAEAIESIEVLRGPAAA 144 Query: 159 RYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTEN-LSYR 217 RYG+GAAGGVVNIITK+ ETHG++ Y++ P+ EG+S R+ F ++GPL ++ LSYR Sbjct: 145 RYGSGAAGGVVNIITKKVTNETHGSVEFYTSQPEDSKEGSSNRVGFNVSGPLIKDVLSYR 204 Query: 218 VYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFE 277 +YGN KT++DD DIN K G+ AGREGV+NKDI G L+W+ T +QT+ + Sbjct: 205 LYGNYNKTEADDVDIN---------KSIGSTAAGREGVKNKDISGRLAWQATDQQTVLLD 255 Query: 278 AGFSRQGNIYTGDTQ---NTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLAYLQ 334 S+QGNIY+GD+Q N ++ + Q++G ETN MYR++Y++TH G+W +G S Q Sbjct: 256 ISSSKQGNIYSGDSQLNANAEADAILSQLIGKETNTMYRDSYALTHEGDWSWGKSKLVAQ 315 Query: 335 YEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLGSEW 394 Y+KT N R+ EGLAG EG + N T+ L L +GE N+P Q LT+G+EW Sbjct: 316 YDKTHNKRLPEGLAGSVEGKIN-NLDDKATSRLETLRFNGEANIPFEYYLPQVLTVGTEW 374 Query: 395 TEQKLDDPSSNTQNTEEGGSIPG--LAGKNRSSSSSARIFSLFAEDNIELMPGTMLTPGL 452 E + D S TQ + GS G LA +RS S RI S + EDN+++ T + GL Sbjct: 375 VEDRFKDNVSTTQGKDSSGSGYGDQLAKGDRSKMES-RIASAYIEDNLKVTDSTDVVLGL 433 Query: 453 RWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQ 512 R+D H G NWSPSLN++ L + TLK G+A+AYKAPN+YQ YLL + G GC Sbjct: 434 RFDDHSKSGSNWSPSLNITQKLNDYFTLKGGVAKAYKAPNMYQNAEGYLLSTNGNGCPAN 493 Query: 513 STS-CYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGG 571 S C L+GN LK ETSVNKELGI++ D + A LT+FRNDYK+KI +G V G Sbjct: 494 IESRCLLQGNGDLKPETSVNKELGIQFQKDIVNASLTWFRNDYKDKIVAGTHVVGTVDGS 553 Query: 572 KGDYANAA-------IYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETG 624 + A I +WEN PKA+++G EG+L L D ++W+NN TYM+ SK+K+TG Sbjct: 554 STNANTGAVTNTKWNILRWENTPKALIQGFEGSLGLDFGD-IRWTNNFTYMMDSKDKQTG 612 Query: 625 DVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRV-----TGSANDQL 679 + LS+ P YT+NS+ D+ TD L + T YG+QK ++ + +R+ +G AN L Sbjct: 613 NPLSLVPIYTINSIFDYDITDQLDVNFVFTQYGRQKSRQ--FAENRLESGIGSGGANSAL 670 Query: 680 SP-----YAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEP 734 P Y+ AG+ Y+ S +S GV NLFDK++ R N+ + TYNEP Sbjct: 671 KPSTVKSYSTAGINVGYKFSDQISTRVGVSNLFDKQILRDSNSI---------SQTYNEP 721 Query: 735 GRTFYTSLTASF 746 GR +Y SL SF Sbjct: 722 GRAYYASLKYSF 733 >2HDF-A nrPDB Length = 639 Score = 542 bits (1396), Expect = e-154, Method: Composition-based stats. Identities = 238/736 (32%), Positives = 358/736 (48%), Gaps = 118/736 (16%) Query: 32 SVIELGEQTVV--ATAQEETKQAP-GVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNS 88 SV + GE VV ++ ++ K AP +S+IT ED+ ++P N L +++ +PGV LT Sbjct: 1 SVDDDGETMVVTASSVEQNLKDAPASISVITQEDLQRKPVQN-LKDVLKEVPGVQLTNEG 59 Query: 89 SSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVER 148 N + + IRG+ TLILVDGK V+SRN+V R + D NW+P D +ER Sbjct: 60 -----DNRKGVSIRGLDSSYTLILVDGKRVNSRNAVF------RHNDFDLNWIPVDSIER 108 Query: 149 IEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNG 208 IEV+RGP ++ YG+ A GGVVNIITK+ G + G ++V + +H+ G + F +G Sbjct: 109 IEVVRGPMSSLYGSDALGGVVNIITKKIGQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSG 168 Query: 209 PLTEN-LSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWR 267 PL + L + YG++AK + DD N T G P EG ++D + +W Sbjct: 169 PLIDGVLGMKAYGSLAKREKDD-------PQNSTTTDTGETPR-IEGFSSRDGNVEFAW- 219 Query: 268 LTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFG 327 TP Q +F AG Y D Q+ +S++ K NR+ R+ YSV+H G WD+G Sbjct: 220 -TPNQNHDFTAG-------YGFDRQDRDSDSLDK-------NRLERQNYSVSHNGRWDYG 264 Query: 328 SSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQT 387 +S EK N +P N+ T+ T G+ LPL Q Sbjct: 265 TSELKYYGEKVENK--------------NPGNSSPITSESN--TVDGKYTLPL-TAINQF 307 Query: 388 LTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPGTM 447 LT+G E K+ D + T T SS +SA ++LF ED + Sbjct: 308 LTVGGEMRHDKMSDAVNLTGGT--------------SSKTSASQYALFVEDEWRIFEPLA 353 Query: 448 LTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQ 507 LT G+R D H+ G++WSP L + T+ VT+K G A A+KAP+L QL+PD+ Sbjct: 354 LTTGVRMDDHETYGEHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWT----SN 409 Query: 508 GCYGQSTSCYLRGNDGLKAETSVNKELGIEYS-----HDGLVAGLTYFRNDYKNKIESGL 562 C G +C + G+ LK ETS + ELG+ Y +G+ + +T FRND K++I Sbjct: 410 SCRG---ACKIVGSPDLKPETSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISR 466 Query: 563 SPVDHASGGKGDYA---------NAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLT 613 + +A+ G ++ ++ + NV KA ++G+E L +P D K S N T Sbjct: 467 TSDVNAAPGYQNFVGFETGANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYT 526 Query: 614 YMLQSKNKETGD-VLSVTPRYTLNSMLDWQ--ATDDLSLQATVTWYGKQKPKKYDYHGDR 670 Y + LS P +T N LDW+ A +D S+ + + G+ K+ D + Sbjct: 527 YNDGRDVSNGENKPLSDLPFHTANGTLDWKPLALEDWSMYMSGHYTGQ---KRADSATAK 583 Query: 671 VTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAAT 730 G Y I G ++++K++ L AGV NL DK L R + Sbjct: 584 TPGG-------YTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSR-------------DDYS 623 Query: 731 YNEPGRTFYTSLTASF 746 YNE GR ++ ++ F Sbjct: 624 YNEDGRRYFMAVDYRF 639 >5FP1-A nrPDB Length = 718 Score = 430 bits (1105), Expect = e-120, Method: Composition-based stats. Identities = 155/762 (20%), Positives = 272/762 (35%), Gaps = 148/762 (19%) Query: 51 QAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTL 110 P + ++ + + L+ +RT+PG+ L G G +R IRG E+++ Sbjct: 39 DTPKSVSVISKQLIEDTKVTTLADALRTVPGITL-GAGEGGNPNGDRPF-IRGYSSESSM 96 Query: 111 ILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVN 170 + + +S+N + VE++EV +G A+A G G+ GG +N Sbjct: 97 YIDGIRNSTSQNREMFA------------------VEQVEVTKGSASAMGGAGSVGGSIN 138 Query: 171 IITK------------QAGAETHGNLS-------------------------VYSNFPQH 193 +I+K AG + + ++ SN ++ Sbjct: 139 MISKVAKKGDFLEGSVAAGTDNYQRITLDGNKDFGNGIAARVAVLGHQNEKAGQSNGAEY 198 Query: 194 KAEGASERMSFGLNGPLTENLSYRVYGNIAKTDSDD--WDINAGHESNRTGKQAGTLPAG 251 K G + ++FGL+ P LSY K DS WD + G GK A Sbjct: 199 KRVGIAPSITFGLDTPTRATLSYYYLQTDDKPDSGIPYWDSSLGKAQ---GKPAEVKQGT 255 Query: 252 REGVRNKDIDGL--------LSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQM 303 G +++D L LT T+ A +++ N Y + + N K + Sbjct: 256 YYGWKDRDFQKQENHIGTIKLEHDLTDNITITNTAMYAKSKNDYVWTNPDDSKGNVGKGL 315 Query: 304 LGHETNRMYRETYSVTHR----GEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNN 359 + H N ++ + T + G++D G +L++ R N G E + Sbjct: 316 VWHRLNSAITDSETFTDQLALTGKFDTG----FLKH------RFNVG----AEYSKQKTD 361 Query: 360 AGFYTATLRDLTAHGEVNLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLA 419 G Y + A G V+ Y L + W L+ P+ + + P Sbjct: 362 KGGYNI----IDAKGNVSSTGF--YSDCSDLSTNWCTS-LNGPTQKP-FVDRLQARPDFD 413 Query: 420 GKNRSSSSSARIFSLFAEDNIELMPGTMLTPGLRWDHHDIVGDNW---SPSLNLSHALTE 476 S+ S++ DNIE+ P +L GLRWD + + S + + ++ Sbjct: 414 ATVEST-------SVYLLDNIEITPKWLLDLGLRWDKFEAEQNFLATSSAAAYTAKNNSD 466 Query: 477 RVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGC---YGQSTSCYLRGNDGLKAETSVNKE 533 VT +AGI +K + Y + G +G ++ N + E + E Sbjct: 467 FVTYQAGI--TFKPTENGSIYTSYATSASPVGLNAGWGDNSETINANNQMIDPEEAQTFE 524 Query: 534 LGIEY--SHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVV 591 +G ++ + L FR + +N + P +A NV ++ V Sbjct: 525 IGTKWDFLDNHLNLTAAIFRTEKQN-TRVQIDPTTYA----------------NVGESKV 567 Query: 592 EGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQATDDLSLQA 651 +G E L + D S TY+ K S + T S+ + ++ QA Sbjct: 568 DGFELGLNGEITDKWNISAGYTYLDSELTKNGKSCRS--GKCTDQSIYNGNQMPNVPKQA 625 Query: 652 TVTWYGKQKPKKYD-----YHGDRVTGS-ANDQLSP-YAIAGLGGTYRLSKNLSLGAGVD 704 W + + + D+V G AN + P Y Y ++KN+ L ++ Sbjct: 626 ATLWTTYKVLPQLTVGAGAVYSDKVYGDVANTKWVPSYVRYDAMARYNVNKNVDLQLNIN 685 Query: 705 NLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTASF 746 NL DKR F A GR+ ++ + Sbjct: 686 NLSDKRYFTK---------AYASHYATEAEGRSAVLAVNFKY 718 >6E4V-A nrPDB Length = 693 Score = 408 bits (1049), Expect = e-114, Method: Composition-based stats. Identities = 156/744 (20%), Positives = 261/744 (35%), Gaps = 117/744 (15%) Query: 27 GQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTG 86 G+ D SV T + Q P I ++ + L +++ G++ + Sbjct: 20 GENDYSVTSTSAGTKMQMTQR---DIPQSVTIVSQQRMEDQQLQTLGEVMENTLGISKSQ 76 Query: 87 NSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQV 146 S +R I +VDG P + G Sbjct: 77 ADSDRALYYSRGFQI-------DNYMVDGIPTYFESRWNLGDALS----------DMALF 119 Query: 147 ERIEVIRGPAAARYGNGAAGGVVNIITKQAGA-ETHGNLSVYSNFPQHKAEGASERMSFG 205 ER+EV+RG G G +N++ K A + E G++S ER Sbjct: 120 ERVEVVRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSA------EYGSWNKERYVAD 173 Query: 206 LNGPLTEN--LSYRVYGNIAKTDS--DDWDINAGHESNRTGKQAGTLPAGREGVRNKDID 261 L PLTE+ + R+ G DS D ++ S G L G + ID Sbjct: 174 LQSPLTEDGKIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTTLSAGYEYQRID 233 Query: 262 -GLLSWRLTPEQTLEFEA-GFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVT 319 +W P + + + R + N N V L + ++ T + T Sbjct: 234 VNSPTWGGLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQQFADTWQATLNAT 293 Query: 320 HRGEWDFGSSLAYLQYEKTRNSRIN--EGLAGGTEGIFDPN---------NAGFYTATLR 368 H E +F S + Y+ ++ +N +G+ G + P N+G Sbjct: 294 H-SEVEFDSKMMYV------DAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDAL 346 Query: 369 DLTAHGEVNLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQ-NTEEGGSIPGLAG------- 420 DL A G L G + L G +++Q SS +E GS G Sbjct: 347 DLFADGSYEL---FGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDW 403 Query: 421 --KNRSSSSSARIFSLFAEDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTERV 478 ++ + + + SL+A + L L G R+ + + D + S+ +H Sbjct: 404 SPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRV--DTLTYSMEKNHT----- 456 Query: 479 TLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDG------LKAETSVNK 532 T AG+ ++ +N ++ Y TS + ND L T N Sbjct: 457 TPYAGL--------VFDINDNW-------STYASYTSIFQPQNDRDSSGKYLAPITGNNY 501 Query: 533 ELGI--EYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAV 590 ELG+ ++ + L L FR + N +S +P+ G G+ A A V V Sbjct: 502 ELGLKSDWMNSRLTTTLAIFRIEQDNVAQSTGTPI---PGSNGETAYKA------VDGTV 552 Query: 591 VEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQ--ATDDLS 648 +G+E L + D + + T + N E V PR T+ ++ +L+ Sbjct: 553 SKGVEFELNGAITDNWQLTFGATRYIAEDN-EGNAVNPNLPRTTVKMFTSYRLPVMPELT 611 Query: 649 LQATVTWYGKQKPKKYDYHGDRV--TGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNL 706 + V W + + D V G+ + YA+ L Y+++KN SL V+NL Sbjct: 612 VGGGVNWQNR-------VYTDTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNNL 664 Query: 707 FDKRLFRAGNAQGVVGIDGAGAAT 730 FDK N +G + + Sbjct: 665 FDKTY--DTNVEGSIVYGTPRNFS 686 >3FHH-A nrPDB Length = 640 Score = 354 bits (908), Expect = 8e-98, Method: Composition-based stats. Identities = 148/705 (20%), Positives = 261/705 (37%), Gaps = 121/705 (17%) Query: 40 TVVATAQEETK-QAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQ 98 TV AT + +AP + + + + + ++R +PG+ L G R N + Sbjct: 5 TVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTG----RTNGQD 60 Query: 99 IDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAA 158 I++RG L+LVDG +G + ++ ++R+E++RGP+A Sbjct: 61 INMRGYDHRGVLVLVDGIR-----------QGTDTGHLNGTFLDPALIKRVEIVRGPSAL 109 Query: 159 RYGNGAAGGVVNIITKQAGAE-THGNLSVYSNFPQHKAEGASERMSFGLNGPL---TENL 214 YG+GA GGV++ T A G S + F G + S GL TENL Sbjct: 110 LYGSGALGGVISYDTVDAKDLLQEGQSSGFRVF----GTGGTGDHSLGLGASAFGRTENL 165 Query: 215 SYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTL 274 G +A + D D+ + G E + N G +W++ Q+L Sbjct: 166 D----GIVAWSSRDRGDLRQSN---------GETAPNDESINNMLAKG--TWQIDSAQSL 210 Query: 275 EFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHET-NRMYRETYSVTHRGEWDFGSSLAYL 333 + + Q ++ M+ T R + +Y + +G D+ ++ A + Sbjct: 211 SGLVRYYNNDAREPKNPQTVEASESSNPMVDRSTIQRDAQLSYKLAPQGN-DWLNADAKI 269 Query: 334 QYEKTRNSRINEGLAGG-----TEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTL 388 + + R + N G +G T+G N + + + L Sbjct: 270 YWSEVRINAQNTGSSGEYREQITKGARLENRSTLFADSFAS----------------HLL 313 Query: 389 TLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMP-GTM 447 T G E+ Q + S + + GG+ G SS + +D I L Sbjct: 314 TYGGEYYRQ--EQGSHHHHHHHPGGATTGFPQAKIDFSSG------WLQDEITLRDLPIT 365 Query: 448 LTPGLRWD--------HHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPD 499 L G R+D + D+ D WS ++ T + L A+A++AP + ++ D Sbjct: 366 LLGGTRYDSYRGSSDGYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYND 425 Query: 500 YLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELG-------IEYSHDGLVAGLTYFRN 552 +S G+ + Y N L+ ET+ +E G + S+D L +YF Sbjct: 426 SKHFS-----IGRFYTNYWVPNPNLRPETNETQEYGFGLRFDDLMLSNDALEFKASYFDT 480 Query: 553 DYKNKIESGLSPVDHASGGKGDY--ANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSN 610 K+ I + VD A+ Y NA I+ W+ + K + L + Sbjct: 481 KAKDYIS---TTVDFAAATTMSYNVPNAKIWGWDVMTKYTTDLF----------SLDVAY 527 Query: 611 NLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDR 670 N T K+ +TG+ +S T+ S L+ +V W G + Sbjct: 528 NRTR---GKDTDTGEYISSINPDTVTSTLN---IPIAHSGFSVGWVGTFADRSTHISS-- 579 Query: 671 VTGSANDQLSPYAIAGLGGTY---RLSKNLSLGAGVDNLFDKRLF 712 + + Y + +Y + K ++ + N FDK + Sbjct: 580 ----SYSKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYW 620 >6FOK-A nrPDB Length = 723 Score = 288 bits (735), Expect = 9e-78, Method: Composition-based stats. Identities = 165/768 (21%), Positives = 259/768 (33%), Gaps = 107/768 (13%) Query: 5 ALPAVPFLLLSSCLLANAVHAAGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIA 64 A A+ L LS L H+ Q +EL V AQ ++I+T Sbjct: 37 AFAALCGLALSPSALLAEEHS--QHQDHAVELAPSVVTGVAQSSP-----LTIVTNPKEP 89 Query: 65 KRP-PSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNS 123 ++P P++D + ++T+PG + N G+N +RGM IL +G + Sbjct: 90 RQPVPASDGADYLKTIPGFAVIRNG-----GSNGDPVLRGMFGSRLNILTNGGMM----- 139 Query: 124 VRYGWRGERDSRGD--TNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETH 181 G +R D T+++ + +++ VI+GP +G GA+ G I + E Sbjct: 140 -----LGACPNRMDAPTSYISPETYDKLTVIKGPQTVLWGPGASAGT---ILFEREPERF 191 Query: 182 GNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSY-RVYGNIAKTDSDDWDINAGHESNR 240 G L N G++ R L+ L Y R GN A+ SDD++ AG+ Sbjct: 192 GELGSRVN--ASLLAGSNGRFDKVLDAAAGNRLGYLRFTGNHAQ--SDDYEDGAGN---- 243 Query: 241 TGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYV 300 R + + D + W + +E AG Y G Sbjct: 244 -------TVPSR--WKKWNGDVAVGWTPDEDTLIELTAGKGDGEARYAG----------- 283 Query: 301 KQMLGHETNRMYRETYSVTHRGEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNA 360 + M G + R V A + Y + N L P Sbjct: 284 RGMDGSQFKRESLGLRFVKSNVSDVLEKVEAQVYYNYADHIMDNFRLRTPDPSSMMP--- 340 Query: 361 GFYTATLRDLTAHGEVNLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAG 420 + + T G + + +T + S T+ Sbjct: 341 MPMASQVDRRTLGGRLAATWRWDDFKLVTGVDAMRNEHRARGSKYDMMTDY---YTDADQ 397 Query: 421 KNRSSSSSARIFSLFAEDNIELMPGTMLTPGLRWDHHDI--------VGDNWSPSLNLSH 472 S + + F E L GLR D + G N + Sbjct: 398 FPWSKDAVFHNYGAFGELTWFAAERDRLIGGLRLDRASVKDYRQTLKSGHMGHAMANPTA 457 Query: 473 ALTERVTLKAGIAR-----AYKAPNLY------QLNPD-YLLYSRGQGCYGQSTSCYLRG 520 T TL +G R A LY + PD + L+S +G G + Sbjct: 458 NDTRADTLPSGFVRYEHDLADSPTTLYAGLGHAERFPDYWELFSPKRGPNGSVNAF---- 513 Query: 521 NDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAI 580 D +K E + + G++Y+ D L A + + D + + Sbjct: 514 -DKIKPEKTTQLDFGLQYNGDKLQAWASGY----------VGVVQDFILFSYREGMMGSS 562 Query: 581 YQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLD 640 Q NV A + G E + L K +L Y KN L P L Sbjct: 563 TQATNVD-ARIMGGELGASYQLTGNWKTDASLAYAW-GKNSSDDRALPQIPPLEARFGLT 620 Query: 641 WQATDDLSLQATVTWYGKQKPKKYDYHGDR--VTGSANDQLSPYAIAGLGGTYRLSKNLS 698 + ++ A W + + D+ V G D+ + + + L G YR+++N+ Sbjct: 621 Y---EEGDWSAGSLW--RVVAPQNRIARDQGNVVGKDFDKSAGFGVFSLNGAYRVTRNVK 675 Query: 699 LGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTASF 746 L AGVDNLFDK N G G + T EPGRTF+T + SF Sbjct: 676 LSAGVDNLFDKDYTEHLNKAGDAGFGFSANETVPEPGRTFWTKVDFSF 723 >5FOK-A nrPDB Length = 730 Score = 249 bits (635), Expect = 3e-66, Method: Composition-based stats. Identities = 143/805 (17%), Positives = 242/805 (30%), Gaps = 167/805 (20%) Query: 23 VHAAGQ---GDGSVIELGEQTVVATAQEETK----------------QAPGVSIITAEDI 63 ++ AGQ V+ L T+V Q+ET P + + + Sbjct: 1 MNEAGQKKTDKDRVLSLDAATIVGEQQDETTYNVDRSASKKYTAPLLDTPKTVTVIPQQV 60 Query: 64 AKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNS 123 K + L+ +RT PG+ G G +R IRG E+ L + V+S+ Sbjct: 61 IKDTGALTLADALRTTPGITF-GAGEGGNPAGDRPF-IRGFNAESDTFLDGMRDVASQTR 118 Query: 124 VRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGN 183 + VE+IEV +GP +A G G+ GG +N+I+K A + + Sbjct: 119 EVF------------------NVEQIEVSKGPGSAYTGAGSTGGSLNLISKTAKQDNFTD 160 Query: 184 LSVYSNFPQHKAE------------------------------------GASERMSFGLN 207 Q + G + ++FG + Sbjct: 161 AGFTWGSDQTRRTTLDVNRMIGDNAAFRLNLMKHDAHVAGRDEVSVSRWGVAPTVTFGFD 220 Query: 208 GPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDG----- 262 P LSY D N K A G++++D Sbjct: 221 TPTRATLSYYHLSTDDMPDYGLPLTNVNRSKANPSKPASVDRDNFYGLKDRDYRKSTTDS 280 Query: 263 ---LLSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVT 319 + L TL R Y + + N + + Sbjct: 281 GTFRIEHDLNDNLTLSNSTRLVRTTLDYIVSNPDDSRGNVANGYVYRSAKSRNSTSKGWV 340 Query: 320 HRGEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATL---RDLTAHGEV 376 ++ + ++++ L G E ++ + Y T T + + Sbjct: 341 NQTDLKANFETGFIKHT----------LVTGLEFSYEDVHNRPYAITSGGGAGNTCNARL 390 Query: 377 NLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFA 436 T G WT G GLA + + +SA + Sbjct: 391 LASGDCTSLNRPTPGDNWT----------------GSITDGLAYTDTDTKTSA----AYV 430 Query: 437 EDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLN-------LSHALTERVTLKAGIARAYK 489 D ++L L GLR+D D + + + + G+ YK Sbjct: 431 FDTLKLSEQWELNLGLRYDDFDTKSSGYQTAGRNGPAGYFKRENNSHFWNYQTGLV--YK 488 Query: 490 APNLYQLNPDYLLYSRGQG-CYGQSTSCYLRGNDGLKAETSVNKELGIEYS--HDGLVAG 546 + + S G G+ + GN+GL E + N ELG +++ D L Sbjct: 489 PAPNGSIYLAWSTSSNPTGETGGEGQADISVGNNGLDPERNRNLELGTKWAFFDDALSLN 548 Query: 547 LTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGL 606 FR D N + + V+G+E L + Sbjct: 549 AALFRTDKTNARVASPDVSTLQVLD---------------GEQRVQGVELGFNGKLTEKW 593 Query: 607 KWSNNLTYMLQSKNKET--GDVLSVTPRYTLNSMLDW---QATDDLSLQATVTWYGKQKP 661 K TY+ K T D + P+ N+ W + ++ T+ KQ Sbjct: 594 KVFGGYTYLDSEIRKSTVKSDEGNKMPQTAQNNFTLWTTYDLLQNFTIGGGTTYVDKQ-- 651 Query: 662 KKYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVV 721 +G+ + + Y +Y++SKN+ L V NL DKR F + + Sbjct: 652 -----YGNTA---NSTYIPSYWRYDAMASYKVSKNVDLQLNVQNLTDKRYFDQVYSTHMA 703 Query: 722 GIDGAGAATYNEPGRTFYTSLTASF 746 + PGRT + F Sbjct: 704 HVA---------PGRTALLGVNFHF 719 >5NEC-A nrPDB Length = 741 Score = 249 bits (634), Expect = 5e-66, Method: Composition-based stats. Identities = 129/805 (16%), Positives = 241/805 (29%), Gaps = 152/805 (18%) Query: 22 AVHAAGQ---GDGSVIELGEQTVVATAQEETK----------------QAPGVSIITAED 62 A++ AGQ V+ L T+V Q+ET P + + Sbjct: 1 AMNEAGQKKTDKDRVLSLDAATIVGEQQDETTYNVDRSASKKYTAPLLDTPRSVTVVPKQ 60 Query: 63 IAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRN 122 + K + L +RT+PG+ G G +R IRG ++ + + ++ Sbjct: 61 VIKDTAAVSLQDALRTVPGITF-GAGEGGNPTGDRPF-IRGFDAQSDTYVDGVRDTGAQT 118 Query: 123 SVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHG 182 + +E+IEV +GP +A G G+AGG +N+++KQA A Sbjct: 119 REIF------------------NLEQIEVSKGPNSAFGGRGSAGGSLNLVSKQAKAGNFI 160 Query: 183 NLSVYSNFPQHKAE-------------------------------------GASERMSFG 205 + Q + G + ++FG Sbjct: 161 DGGFTYGSDQTRRYTLDLNQEFLDGNAAFRLNLLKHDANVAGRDEVDVSRWGVAPSLTFG 220 Query: 206 LNGPLTENLSYRVYGNIAKTDSDD-WDINAGHESNRTGKQAGTLPAGREGVRNKDIDGL- 263 L P +S+ + DS + ++ + K G+ +D Sbjct: 221 LGSPTRVTVSHYHLESDDTPDSGIPYAKSSDRSKHNPDKPVNVDRGNFYGLTGRDFQKSR 280 Query: 264 -------LSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETY 316 + LT T+ + + Y + + N + N T Sbjct: 281 IDTSTITVEHDLTDSLTIRNTSRYGNSHQDYLWTQPDDSQGNINNGSVWRRQNNRVSTTT 340 Query: 317 SVTHRGEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEV 376 + ++ + + + + G E + + Y + Sbjct: 341 TAVNQTDL----------FGEFYLGGFKNSFSTGLEFSREDSKRDGYIVDTNTGLGSNKC 390 Query: 377 NLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFA 436 N + S + L++P N + G A N + +++A Sbjct: 391 N-------PSLIGAPSGYNCTSLENP--NPHDPWNGSITRKYAPLN----TVGTTKAIYA 437 Query: 437 EDNIELMPGTMLTPGLRWDHHDIVGDNWSPS-LNLSHALTERVTLKAGIARAYKAPNLYQ 495 D I+L + G R+D + N + +AG+ +K Sbjct: 438 FDTIDLNEQWQVNIGARFDSFETTAKNHGVRPATKLSDKSSFWNWQAGLV--WKPVPNGS 495 Query: 496 LNPDYLLYSRGQGCYGQSTSCYLRGND-----GLKAETSVNKELGIEYS--HDGLVAGLT 548 + Y + G + + L+ E + N ELG +++ ++ L Sbjct: 496 IYASYATSATPPGSMLDNGDTSNAVDGFAISNNLEPEETTNYELGTKWAFFNERLELSAA 555 Query: 549 YFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKW 608 FR D N A ++N ++ V+G+E + + L + K Sbjct: 556 IFRTDKDN-----------------TRILVANQTYDNAGQSRVDGVELSASGKLTEKWKV 598 Query: 609 SNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYD--- 665 +Y+ + + S + + + W K Sbjct: 599 FAGYSYLDSELVDAGKAGRNGNVNASAASN-NGNEMPNTPKNSFSLWTTYDIFPKTTIGG 657 Query: 666 --YHGDRVTGS-ANDQLSP-YAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVV 721 ++ D+V G N P Y +Y+LSKN+ V N+FDK+ F Sbjct: 658 GAFYVDKVYGDVGNTVYVPDYWRYDAMASYKLSKNVDFQLNVQNVFDKKYFDK------- 710 Query: 722 GIDGAGAATYNEPGRTFYTSLTASF 746 A GRT S F Sbjct: 711 --AYAAHYASQAAGRTILFSTNFHF 733 >1NQH-A nrPDB Length = 594 Score = 194 bits (491), Expect = 2e-49, Method: Composition-based stats. Identities = 144/737 (19%), Positives = 241/737 (32%), Gaps = 169/737 (22%) Query: 35 ELGEQTVVATAQE----ETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSS 90 + T+V TA + +++T +DI R S ++ ++R +PGV++T N S Sbjct: 2 DTSPDTLVVTANRFEQPRSTVLAPTTVVTRQDI-DRWQSTSVNDVLRRLPGVDITQNGGS 60 Query: 91 GQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIE 150 GQ + I IRG + L+L+DG ++ D + P V+R+E Sbjct: 61 GQLSS---IFIRGTNASHVLVLIDGVRLN---------LAGVSGSADLSQFPIALVQRVE 108 Query: 151 VIRGPAAARYGNGAAGGVVNIIT--KQAGAETHGNLS--VYSNFPQHKAEGASERMSFGL 206 IRGP +A YG+ A GGVVNIIT + G E Y N+ + ++ L Sbjct: 109 YIRGPRSAVYGSDAIGGVVNIITTRDEPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTL 168 Query: 207 NGPLTENLSYRV-----YGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDID 261 G Y V G A+TD+D G +K + Sbjct: 169 LGDYAHTHGYDVVAYGNTGTQAQTDND-------------------------GFLSKTLY 203 Query: 262 GLLSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHR 321 G L T + GF R Y D + Y +T ++Y +++ R Sbjct: 204 GALEHNFTDAWS-----GFVRG---YGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLR 255 Query: 322 GEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLH 381 + S Y +++ N H Sbjct: 256 YNGELIKSQLITSYSHSKD-----------------------------------YNYDPH 280 Query: 382 LGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIE 441 G + E + + ++ G+ + + + + ED + Sbjct: 281 YGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAGVDWQKQTTTPGTG------YVEDGYD 334 Query: 442 LMPGTMLTPGL------------RWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYK 489 + GL R D + G + + + E A +YK Sbjct: 335 QRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYK 394 Query: 490 APNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTY 549 APNL QL Y GN L E S E E G+ ++ Sbjct: 395 APNLGQLYGFY-------------------GNPNLDPEKSKQWEGAFEGLTAGVNWRISG 435 Query: 550 FRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWS 609 +RND + I+ ++ N KA ++G+E T L + Sbjct: 436 YRNDVSDLIDYDDHT----------------LKYYNEGKARIKGVEATANFD-TGPLTHT 478 Query: 610 NNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGD 669 + Y+ +N T L + + LDWQ D T + G + K Y + Sbjct: 479 VSYDYVDA-RNAITDTPLLRRAKQQVKYQLDWQ-LYDFDWGITYQYLGTRYDKDYSSYPY 536 Query: 670 RVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAA 729 + ++ ++ L Y ++ +L++ + NLFDK Sbjct: 537 QTV-----KMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDY--------------ETVY 577 Query: 730 TYNEPGRTFYTSLTASF 746 Y GR + S + +F Sbjct: 578 GYQTAGREYTLSGSYTF 594 >2W78-A nrPDB Length = 772 Score = 175 bits (443), Expect = 6e-44, Method: Composition-based stats. Identities = 129/713 (18%), Positives = 227/713 (31%), Gaps = 97/713 (13%) Query: 49 TKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPEN 108 ++ P + N++ ++R PG+ ++ + + RG N Sbjct: 119 PRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDT-----DRNNYYARGFSINN 173 Query: 109 TLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGV 168 DG P ++RN +R+EV++G G G+ G Sbjct: 174 FQY--DGIPSTARNV---------GYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGAT 222 Query: 169 VNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTE--NLSYRVYGNIAKTD 226 +N+I K+ E G++ + + R ++GPLTE N+ R Sbjct: 223 INLIRKKPTHEFKGHVEL------GAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKH 276 Query: 227 S--DDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFEAGFSRQG 284 S D ++ G +D D S + F F QG Sbjct: 277 SFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGS-----GWSGSFPL-FDSQG 330 Query: 285 NIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLAYLQYEKTRNSR-I 343 N + + + NN K + R W + +Q + N Sbjct: 331 NR---NDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGW-----VGKVQLDHKINGYHA 382 Query: 344 NEGLAGGTEGIFDPNNAG-----FYTATLRDLTAHGEVNLPL-HLGYEQTLTLGSE---- 393 G G P+N+ YT + + + P LG E L +G+ Sbjct: 383 PLGAIMGDWPA--PDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFS 440 Query: 394 -------WTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPGT 446 W + D+ + + N + P ++ R + + Sbjct: 441 HWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDL 500 Query: 447 MLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRG 506 L G R + + G LN + + R G Y + Y + Y Sbjct: 501 NLFLGGRVVDYRVTG------LNPTIRESGRFIPYVG--AVYDLNDTYSVYASYTDIFMP 552 Query: 507 QGCYGQSTSCYLRGNDGLKAETSVNKELGI--EYSHDGLVAGLTYFRNDYKNKIESGLSP 564 Q + + +S L L+ + N E+GI EY L L YF +N+ E Sbjct: 553 QDSWYRDSSNKL-----LEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALY 607 Query: 565 VDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETG 624 + YA I KA +G E ++ LA G + T+ + + Sbjct: 608 NSKPTNPAITYAYKGI-------KAKTKGYEAEISGELAPGWQVQAGYTHKIIRDD-SGK 659 Query: 625 DVLSVTPRYTLNSMLDWQ---ATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSP 681 V + P+ L+ ++ A D L++ W GK + + + Sbjct: 660 KVSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSW---QMVYNNPRSRWEKFSQED 716 Query: 682 YAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEP 734 Y + L Y+++ LS V+N+FDK + I +A+Y +P Sbjct: 717 YWLVDLMARYQITDKLSASVNVNNVFDKTYY--------TNIGFYTSASYGDP 761 >1XKH-A nrPDB Length = 687 Score = 172 bits (435), Expect = 5e-43, Method: Composition-based stats. Identities = 129/713 (18%), Positives = 227/713 (31%), Gaps = 97/713 (13%) Query: 49 TKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPEN 108 ++ P + N++ ++R PG+ ++ + + RG N Sbjct: 34 PRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDT-----DRNNYYARGFSINN 88 Query: 109 TLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGV 168 DG P ++RN +R+EV++G G G+ G Sbjct: 89 FQY--DGIPSTARNV---------GYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGAT 137 Query: 169 VNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTE--NLSYRVYGNIAKTD 226 +N+I K+ E G++ + + R ++GPLTE N+ R Sbjct: 138 INLIRKKPTHEFKGHVEL------GAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKH 191 Query: 227 S--DDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFEAGFSRQG 284 S D ++ G +D D S + F F QG Sbjct: 192 SFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGS-----GWSGSFPL-FDSQG 245 Query: 285 NIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLAYLQYEKTRNSR-I 343 N + + + NN K + R W + +Q + N Sbjct: 246 NR---NDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGW-----VGKVQLDHKINGYHA 297 Query: 344 NEGLAGGTEGIFDPNNAG-----FYTATLRDLTAHGEVNLPL-HLGYEQTLTLGSE---- 393 G G P+N+ YT + + + P LG E L +G+ Sbjct: 298 PLGAIMGDWPA--PDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFS 355 Query: 394 -------WTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPGT 446 W + D+ + + N + P ++ R + + Sbjct: 356 HWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDL 415 Query: 447 MLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRG 506 L G R + + G LN + + R G Y + Y + Y Sbjct: 416 NLFLGGRVVDYRVTG------LNPTIRESGRFIPYVG--AVYDLNDTYSVYASYTDIFMP 467 Query: 507 QGCYGQSTSCYLRGNDGLKAETSVNKELGI--EYSHDGLVAGLTYFRNDYKNKIESGLSP 564 Q + + +S L L+ + N E+GI EY L L YF +N+ E Sbjct: 468 QDSWYRDSSNKL-----LEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALY 522 Query: 565 VDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETG 624 + YA I KA +G E ++ LA G + T+ + + Sbjct: 523 NSKPTNPAITYAYKGI-------KAKTKGYEAEISGELAPGWQVQAGYTHKIIRDD-SGK 574 Query: 625 DVLSVTPRYTLNSMLDWQ---ATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSP 681 V + P+ L+ ++ A D L++ W GK + + + Sbjct: 575 KVSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSW---QMVYNNPRSRWEKFSQED 631 Query: 682 YAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEP 734 Y + L Y+++ LS V+N+FDK + I +A+Y +P Sbjct: 632 YWLVDLMARYQITDKLSASVNVNNVFDKTYY--------TNIGFYTSASYGDP 676 >3EFM-A nrPDB Length = 707 Score = 172 bits (434), Expect = 7e-43, Method: Composition-based stats. Identities = 109/711 (15%), Positives = 199/711 (27%), Gaps = 95/711 (13%) Query: 38 EQTVVATAQE-ETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNN 96 E AT ++ P + + D I+ T PG+++T + S N Sbjct: 35 EAMSTATGLTLSPRETPQSVSVVTRQQIEDQGLTDTGAILATAPGISVTRSDS-----NR 89 Query: 97 RQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPA 156 RG DG + YG + + A + +E++RG Sbjct: 90 YSFSARGF--TIDNFQFDGLVSPILSQWNYG----------STDMDAAIYDHVEIVRGAT 137 Query: 157 AARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSY 216 G+G VN + K+ E F R ++ P+TE+ Sbjct: 138 GLMTGSGNPSAAVNFVRKRPLREFAA------TFNASVGSWDYVRGDADISVPITEDGRI 191 Query: 217 RVYGNIAKTDSDDW----DINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQ 272 R A + D + D V + P Sbjct: 192 RSRLVAAYSQGDSYVHFLDTRRRTFYGVVSADLTPDTVLTTSVEYQHNHSNGFGSGFPLF 251 Query: 273 TLEFE-AGFSRQ-GNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSL 330 + F+R N Q+T + Y L H ++ + +H + + Sbjct: 252 YSDGSRTDFNRSVANNAPWARQDTEATTY-FVDLTHRFTNDWKLRAAYSHT-DGRYLMKH 309 Query: 331 AYLQYEKTRNSRINEGLAGGTEGIFDPNNAG--------FYTATLRDLTAHGEVNLPLHL 382 Y R++ I + + + F LR A G +++ H Sbjct: 310 VYRGGYPDRHTGIIAAPPAFSNYDGNLDRDDIHFSLSAPFEAFGLRHEVALGWMSIDNHS 369 Query: 383 GYEQTLTLGS--------EWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSL 434 ++ +G +W S+ + + + + Sbjct: 370 DIQRYAMVGPAPAIGSFFDWRR-----AGSHHHHHHHIQEPSWADTLSPADDVRTKQTGA 424 Query: 435 FAEDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLY 494 + L L G RW + + + + T AG+ Y Sbjct: 425 YLVGRFALAEPLHLIVGDRWSDWKTKQMYFGSRRE--YRIKNQFTPYAGLT--------Y 474 Query: 495 QLNPDYLLYSRGQGCYGQSTSCYLRGNDG------LKAETSVNKELGIE--YSHDGLVAG 546 +N Y Y T + N L S + ELG++ Y L Sbjct: 475 DINDTYT-------AYASYTEIFQPQNARDTSGGILPPIKSKSYELGLKAAYLEGRLNTS 527 Query: 547 LTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGL 606 F+ N + G + A VEG++ + + Sbjct: 528 AALFQTRQDNLAQV--------IPGSSIPGFPNMQASRAASGAKVEGIDLEASGQILPDW 579 Query: 607 KWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQ---ATDDLSLQATVTWYGKQKPKK 663 + T+ +K+ + + PR ++ A L++ V W + Sbjct: 580 NIGASYTHF-TTKDASGNPINTNHPRSLFKLYTTYRLPGALHRLTVGGGVDWQSRMYQ-- 636 Query: 664 YDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRA 714 G+ + YA+ L + +K LS V+NLFDK+ + Sbjct: 637 ---AAASPRGNVEVEQDSYALVSLMARFDFNKKLSATLNVNNLFDKKYYDQ 684 >1KMO-A nrPDB Length = 774 Score = 165 bits (416), Expect = 9e-41, Method: Composition-based stats. Identities = 120/736 (16%), Positives = 243/736 (33%), Gaps = 100/736 (13%) Query: 37 GEQTVVAT------AQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSS 90 TVV + + A +I ED AK + + +++ +PGV+ N+ + Sbjct: 113 DALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTG-ATTMREVLNRIPGVSAPENNGT 171 Query: 91 GQRGNNRQIDIRGMGPE---NTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVE 147 G IRG+ P + +L+DG PV YG + V ++ Sbjct: 172 GSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPF---APYG-----QPQLSLAPVSLGNMD 223 Query: 148 RIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVY-SNFPQHKAEGASERMSFGL 206 I+V+RG A RYG + GGVVN +T+ + V P E + + Sbjct: 224 AIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPKETHNLMV 283 Query: 207 NGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSW 266 G + + T DW RE + D +L Sbjct: 284 GGTADNGFGTALL--YSGTRGSDW---------------------REHSATRIDDLMLKS 320 Query: 267 RLTPEQTLEFEA--GFSRQGNIYTG--DTQNTNSNNYVKQMLGHET---NRMYRETYSVT 319 + P++ F + + G + +++ + ++ Y Sbjct: 321 KYAPDEVHTFNSLLQYYDGEADMPGGLSRADYDADRWQSTRPYDRFWGRRKLASLGYQFQ 380 Query: 320 HRGEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLP 379 + F Y Q ++ + + + Y+ + EV + Sbjct: 381 PDSQHKFNIQGFYTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVG 440 Query: 380 LHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDN 439 E + ++ ++ + GS P +R + S + + +D Sbjct: 441 YRYLNE---------STHEMRYYTATSSGQLPSGSSP----YDRDTRSGTEAHAWYLDDK 487 Query: 440 IELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPD 499 I++ +TPG+R++H + +N ++ +H + LY L Sbjct: 488 IDIGN-WTITPGMRFEHIESYQNN---AITGTHEEVSYNAPLPALNV------LYHLTDS 537 Query: 500 YLLYSRGQGCYGQSTSCYL---RGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKN 556 + LY+ +G +G + + ++ E + ELG Y L A + F ++ N Sbjct: 538 WNLYANTEGSFGTVQYSQIGKAVQSGNVEPEKARTWELGTRYDDGALTAEMGLFLINFNN 597 Query: 557 KIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYML 616 + +S + + GK + ++ P D + + Y+ Sbjct: 598 QYDSNQTNDTVTARGKTRHTGLETQARYDLGTLT----------PTLDNVSIYASYAYVN 647 Query: 617 QSKNKET---GDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTG 673 ++ G+++ +P++ +D++ + + + Q + + G Sbjct: 648 AEIREKGDTYGNLVPFSPKHKGTLGVDYKP-GNWTFNLNSDFQSSQFADNANTVKESADG 706 Query: 674 SANDQLSPYAIAGLGGTYRLS---KNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAAT 730 S ++ + + G Y +L+L GV N+FD+ F + D Sbjct: 707 S-TGRIPGFMLWGARVAYDFGPQMADLNLAFGVKNIFDQDYF-------IRSYDDNNKGI 758 Query: 731 YNEPGRTFYTSLTASF 746 Y RT Y + F Sbjct: 759 YAGQPRTLYMQGSLKF 774 >4EPA-A nrPDB Length = 655 Score = 160 bits (403), Expect = 3e-39, Method: Composition-based stats. Identities = 132/726 (18%), Positives = 239/726 (32%), Gaps = 123/726 (16%) Query: 31 GSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDL-----SQIIRTMPGVNLT 85 G + E T+V TA +++ ++ + +++ + P +D ++ R +PG+N+ Sbjct: 4 GQTSQQDESTLVVTASKQSSRSASANNVSST-VVSAPELSDAGVTASDKLPRVLPGLNIE 62 Query: 86 GNS-----SSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNW 140 + + RG + D P TL VDG P S N+++ Sbjct: 63 NSGNMLFSTISLRGVSSAQDF--YNPAVTLY-VDGVPQLSTNTIQ--------------- 104 Query: 141 VPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASE 200 V+ +E++RGP YG A GG++NI+T+Q + G + + S Sbjct: 105 -ALTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDSTPRGYIEGGVSSR------DSY 157 Query: 201 RMSFGLNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDI 260 R F L+GP+ + L Y + + D D A G A V+ + Sbjct: 158 RSKFNLSGPIQDGLLYGSVTLLRQVDDGDMINPAT-----GSDDLGGTRASIGNVKLRLA 212 Query: 261 DGLLSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTH 320 W + + E + Y G N + G M R T S T Sbjct: 213 PDDQPWEMGFAASRECTRA---TQDAYVGW--NDIKGRKLSISDGSPDPYMRRCTDSQTL 267 Query: 321 RGEW---DFGSSLAYLQYEKTRNSRINEG-LAGGTEGIFDPNNAGFYTATLRDLTAHGEV 376 G++ D+ +L ++ + G L ++ + ATL D V Sbjct: 268 SGKYTTDDWVFNLISAWQQQHYSRTFPSGSLIVNMPQRWNQDVQELRAATLGDAR---TV 324 Query: 377 NLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFA 436 ++ L + T +KL+ + ++A + ++ Sbjct: 325 DMVFGLYRQNT--------REKLNSAYDMPTMPYLSSTGY----------TTAETLAAYS 366 Query: 437 EDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLN---LSHALTERVTLKAGIARAYKAPNL 493 + L + G+R+ H L + + ++ Y Sbjct: 367 DLTWHLTDRFDIGGGVRFSHDKSSTQYHGSMLGNPFGDQGKSNDDQVLGQLSAGYM---- 422 Query: 494 YQLNPDYLLYSRGQGCYGQSTSCYLRGND-GLKA---ETSVNKELGIEYSHDGLVAGLTY 549 L D+ +Y+R Y S + K E S+N ELG Y + Sbjct: 423 --LTDDWRVYTRVAQGYKPSGYNIVPTAGLDAKPFVAEKSINYELGTRYETADVTLQAAT 480 Query: 550 FRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWS 609 F K+ ++ PV + N KA G+E A G W Sbjct: 481 FYTHTKD-MQLYSGPV-------------RMQTLSNAGKADATGVELEAKWRFAPGWSWD 526 Query: 610 NNLTYMLQSKNKET----GDVLSVTPRY----TLNSMLD---WQATDDLSLQATVTWYGK 658 N + ++ G+ + PRY ++N ++D L++ Y Sbjct: 527 INGNVIRSEFTNDSELYHGNRVPFVPRYGAGSSVNGVIDTRYGALMPRLAVNLVGPHY-- 584 Query: 659 QKPKKYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQ 718 G + YA ++ ++ +++ VDNLFD+R G Sbjct: 585 ------------FDGDNQLRQGTYATLDSSLGWQATERMNISVYVDNLFDRRYRTYGYMN 632 Query: 719 GVVGID 724 G + Sbjct: 633 GSSAVA 638 >6BPM-C nrPDB Length = 727 Score = 155 bits (391), Expect = 6e-38, Method: Composition-based stats. Identities = 121/754 (16%), Positives = 238/754 (31%), Gaps = 111/754 (14%) Query: 46 QEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMG 105 + +E + K + +L+ ++ +PGV +G I +RG Sbjct: 32 SRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGAD 91 Query: 106 PENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAA 165 N++ + + + S + + E++EVI+GP+ YG A Sbjct: 92 TSNSIYIDGIRDIGSVSRDTF------------------NTEQVEVIKGPSGTDYGRSAP 133 Query: 166 GGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSYRV-YGNIAK 224 G +N+I+KQ + + R + +N + + + R+ Sbjct: 134 TGSINMISKQPRND------SGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKT 187 Query: 225 TDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFEAGFS--R 282 D+ + G A R + + + G+S Sbjct: 188 HDAGRDKVKNERYGVAPSVAFGLGTANRLYLNYLHVTQHNTPDG--GIPTIGLPGYSAPS 245 Query: 283 QGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLAYLQYEKTRNSR 342 G + +++N+ ++ + T H D + ++ + + Sbjct: 246 AGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIN-DNTTIRNTTRWSRVKQDY 304 Query: 343 INEGLAGGTEGIFDPNNA--------GFYTATLRDLTAHGEVNLPLHLG---YEQTLTLG 391 + + GG I P + T + + + NL ++ G Sbjct: 305 LMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTG 364 Query: 392 SEWTEQKLDD--------PSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELM 443 E+T + + P+ N + + GL +++ F+++A D +++ Sbjct: 365 VEFTRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQIT 424 Query: 444 PGTMLTPGLRWDHHDIVGDNWS-------------PSLNLSHALTERVTLKAGIARAYKA 490 L G+R D++ D+ + + +T T K+G +KA Sbjct: 425 RDFELNGGIRLDNYHTEYDSATACGGSGRGAITCPTGVAKGSPVTTVDTAKSGNLMNWKA 484 Query: 491 ------PNLYQLNPDYLLYSRGQG----CYGQSTSCYLRGNDGLKAETSVNKELGIEYS- 539 + +Y + + G QS S K + + E+G ++ Sbjct: 485 GALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKANTSEIGTKWQV 544 Query: 540 -HDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTL 598 L+ FR D +N++E + K VEG E ++ Sbjct: 545 LDKRLLLTAALFRTDIENEVEQNDDGT-----------------YSQYGKKRVEGYEISV 587 Query: 599 TLPLADGLKWSNNLTY----MLQSKN--KETGDVLSVTPRYTLNSMLDWQATDDLSLQAT 652 + + T + K+ ++ L TP + +QATDD+S+ A Sbjct: 588 AGNITPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAG 647 Query: 653 VTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLF 712 + G G Y +A YR+++NL V NLFD Sbjct: 648 ARYIGSMHKGSDGAVGTPAF------TEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYV 701 Query: 713 RAGNAQGVVGIDGAGAATYNEPGRTFYTSLTASF 746 + N G G EP RTF + F Sbjct: 702 ASINKSGYRYHPG-------EP-RTFLLTANMHF 727 >1XKW-A nrPDB Length = 665 Score = 141 bits (354), Expect = 1e-33, Method: Composition-based stats. Identities = 117/741 (15%), Positives = 214/741 (28%), Gaps = 105/741 (14%) Query: 32 SVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSG 91 S + T + + ++ P + + + ++ L + ++ GV + Sbjct: 4 SATQPPGVTTLGKVPLKPRELPQSASVIDHERLEQQNLFSLDEAMQQATGVTVQPFQLLT 63 Query: 92 QRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEV 151 +RG + +DG P N+ ++ ER+E+ Sbjct: 64 T-----AYYVRGF--KVDSFELDGVPALLGNTA-------------SSPQDMAIYERVEI 103 Query: 152 IRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLT 211 +RG +G G VN++ K+ E + ++ R + GPL+ Sbjct: 104 LRGSNGLLHGTGNPAATVNLVRKRPQREFAASTTL------SAGRWDRYRAEVDVGGPLS 157 Query: 212 ENLSYRVYGNIAKTDSDDW----DINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWR 267 + + R A D D + D T G + + ID + + Sbjct: 158 ASGNVRGRAVAAYEDRDYFYDVADQGTRLLYGVTEFDLSPDTLLTVGAQYQHIDSITNMA 217 Query: 268 LTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFG 327 P G SR + + L + G W Sbjct: 218 GVPMAKDGSNLGLSRDTYLDVDWDRFKWDTYRAFGSLEQQLG------------GGWKGK 265 Query: 328 SSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLH-LGYEQ 386 S Y + + + G G Y + +N P+ G Sbjct: 266 VSAEYQEADSRLRYAGSFGAIDPQTGDGGQLMGAAYKFKSIQRSLDANLNGPVRLFGLTH 325 Query: 387 TLTLGSEWTEQKLDD-----------PSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLF 435 L G + + + P + + G P + +++ L+ Sbjct: 326 ELLGGVTYAQGETRQDTARFLNLPNTPVNVYRWDPHGVPRPQIGQYTSPGTTTTTQKGLY 385 Query: 436 AEDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQ 495 A I+L L G R D D + + T G+ ++ Sbjct: 386 ALGRIKLAEPLTLVVGGRESWWD--QDTPATR----FKPGRQFTPYGGL--------IWD 431 Query: 496 LNPDYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGI--EYSHDGLVAGLTYFRND 553 D+ Y Y ++ L E GI E + L L FR D Sbjct: 432 FARDWSWYVSYAEVYQPQADRQTWNSEPLSPVEGKTYETGIKGELADGRLNLSLAAFRID 491 Query: 554 YKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLT 613 +N P Y + K +G E T L S T Sbjct: 492 LEN--NPQEDPDHPGPPNNPFYISG--------GKVRSQGFELEGTGYLTPYWSLSAGYT 541 Query: 614 -----YMLQSKNKETGDVLSVTPRYTLNSMLDWQ---ATDDLSLQATVTWYGKQKPKKYD 665 Y+ S+N + TPR+ L ++ S+ + + D Sbjct: 542 YTSTEYLKDSQNDSGTRYSTFTPRHLLRLWSNYDLPWQDRRWSVGGGL-------QAQSD 594 Query: 666 YHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDG 725 Y D + + YA+ + Y++ ++ + V+NLFD+ +++ + Sbjct: 595 YSVD--YRGVSMRQGGYALVNMRLGYKIDEHWTAAVNVNNLFDRTYYQSLSNPNWNN--- 649 Query: 726 AGAATYNEPGRTFYTSLTASF 746 Y EP R+F SL +F Sbjct: 650 ----RYGEP-RSFNVSLRGAF 665 >1FCP-A nrPDB Length = 705 Score = 132 bits (332), Expect = 5e-31, Method: Composition-based stats. Identities = 114/720 (15%), Positives = 228/720 (31%), Gaps = 133/720 (18%) Query: 54 GVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQID---IRGMGPENTL 110 +S++TAE++A P + + + + PGV++ G RG + D IRG E Sbjct: 31 SISVVTAEEMALHQPKS-VKEALSYTPGVSV------GTRGASNTYDHLIIRGFAAEG-- 81 Query: 111 ILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVN 170 S+N+ G + + + D + +ER E++RGP + YG + GG++N Sbjct: 82 --------QSQNNYLNGLKLQGNFYNDAV-IDPYMLERAEIMRGPVSVLYGKSSPGGLLN 132 Query: 171 IITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSYRVYG-----NIAKT 225 +++K+ E + + G S +G SYR+ G N + Sbjct: 133 MVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLDDDGVY----SYRLTGLARSANAQQK 188 Query: 226 DSD--DWDINAGHESNRTGKQ--------AGTLPAGREGVRNKDIDGLLSWRLTPEQTLE 275 S+ + I K G G K+ + Sbjct: 189 GSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNG-KRLPTD 247 Query: 276 FEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMY--RETYSVTHRGEWDFGSSLAYL 333 F G +T + N HE N + R+ + Sbjct: 248 FNEGAKN-------NTYSRNEKMVGYS-FDHEFNDTFTVRQNLRFAENKTSQNSVYGYGV 299 Query: 334 QYEKTRN-SRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLG-YEQTLTLG 391 + S+ LA +G + L++ + ++ G + TL G Sbjct: 300 CSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDTQLQSKFATGDIDHTLLTG 359 Query: 392 SEWTEQKLD-----------------DPSSNTQNTEEGGSIPGLAGKNRSSS------SS 428 ++ + D +PS + + + K+ ++S + Sbjct: 360 VDFMRMRNDINAWFGYDDSVPLLNLYNPSHHHHHHGSVNTDFDFNAKDPANSGPYRILNK 419 Query: 429 ARIFSLFAEDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTE-RVTLKAGIARA 487 + ++ +D + ++T G R+D ++ + + + + T + G+ Sbjct: 420 QKQTGVYVQDQAQ-WDKVLVTLGGRYDW--ADQESLNRVAGTTDKRDDKQFTWRGGVNYL 476 Query: 488 YKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEY---SHDGLV 544 + N Y G+ + + E+G++Y +V Sbjct: 477 FD--NGVTPYFSYSESFEPSSQVGKDGNIF-------APSKGKQYEVGVKYVPEDRPIVV 527 Query: 545 AGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLAD 604 G Y N + GG + G+E L+ Sbjct: 528 TGAVYNLTKTNNLMADPEGSFFSVEGG----------------EIRARGVEIEAKAALSA 571 Query: 605 GLKWSNNLTYMLQSKNKET---GDVLSVTPRYTLNSMLDWQATD----DLSLQATVTWYG 657 + + TY +T G+ + P++ + D+ D L+L + G Sbjct: 572 SVNVVGSYTYTDAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTG 631 Query: 658 KQKPKKYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSK------NLSLGAGVDNLFDKRL 711 +GD + ++ Y + Y L++ N++L V+NLFD+ Sbjct: 632 -------SSYGDPA---NSFKVGSYTVVDALVRYDLARVGMAGSNVALH--VNNLFDREY 679 >3CSL-A nrPDB Length = 865 Score = 112 bits (278), Expect = 9e-25, Method: Composition-based stats. Identities = 131/813 (16%), Positives = 234/813 (28%), Gaps = 130/813 (15%) Query: 27 GQGDGSVIELGEQTVVAT----AQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGV 82 GDG + L TV+ A + P + + + P+ + I+ G Sbjct: 90 ANGDGGALALDSLTVLGAGGNNANDWVYDEPRSVSVISREQMDNRPARHAADILEQTTG- 148 Query: 83 NLTGNSSSGQRGNNRQIDIRGM-GPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWV 141 SS Q+ ++IRG+ + +DG + + + R T ++ Sbjct: 149 ---AYSSVSQQDPALSVNIRGIQDYGRVNMNIDGMRQNFQ-------KSGHGQRNGTMYI 198 Query: 142 PADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASER 201 ++ + + + +G G GG+ T A + + + Sbjct: 199 DSELLSGVTIDKGTTGGMGSAGTLGGIATFNTVSASDFLAPGKELGGKLHASTGDNGTHF 258 Query: 202 MSFGLNGPLTENLSYRVYGNIAKTDSDDWDINAGHESN-RTGKQAGTLPAGREGVRNKDI 260 + G+ L + + D W N G N R G E ++N I Sbjct: 259 IGSGILA-LGNETGDILLAASERHLGDYWPGNKGDIGNIRINNDTGNYDRYAESIKNNKI 317 Query: 261 D----------GLLSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHET-- 308 + W L Q L+ ++ + G N ++ T Sbjct: 318 PDTHYRMHSRLAKVGWNLPANQRLQLSYLQTQTASPIAGTLTNL-GTRPPYELGWKRTGY 376 Query: 309 ----NRMYRETYSVTHRGEWDFGSSLAYLQYEKTRN--------SRINEGLAGGT----E 352 R YS+ + D+ A L Y T++ S ++ G A T Sbjct: 377 TDVMARNAAFDYSLAPE-DVDWLDFQAKLYYVDTQDDSDTYSTSSLLDNGYATRTRLRTY 435 Query: 353 GIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLGSEW-----TEQKLDDPSSNTQ 407 G N + F A D A+ + + G E ++ T Sbjct: 436 GAQAQNTSRFSLAPGHDFRANYGLEFYYDKATSDSSRQGMEGVTPAGNRSVASLFANLTY 495 Query: 408 NTE-----EGGSIPGL----AGKNRSSSSSARIFSLFAEDN-IELMPGTMLTPGLRWDHH 457 + + EGG S A+ + DN + + T + R + Sbjct: 496 DYDGWLTLEGGLRYDRYRLRGQTGLSYPDLAKDGQRYTIDNPCKALRLTGCSTTTR-EDW 554 Query: 458 DIVGD--NWSPSLNLSHALT-ERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQST 514 D+ D SP+L ++ E + L ++++ P + + + +S Sbjct: 555 DVDRDQGKLSPTLAVAVRPGVEWLELYTTYGKSWRPPAITETLTNGSAHSSST------- 607 Query: 515 SCYLRGNDGLKAETSVNKELG-------IEYSHDGLVAGLTYFRNDYKNKIESGLSPVDH 567 N L+ E S E+G + + D LVA + YF N I +D Sbjct: 608 ---QYPNPFLQPERSRAWEVGFNVQQPDLWFEGDRLVAKVAYFDTKVDNYINL---AIDR 661 Query: 568 ASGGKGDYANAAIYQWENVPKAVVEGLEGTLTL------------------PLADGLKWS 609 G + N+ K GLE L W Sbjct: 662 NKPGLVQPSIGNAAYVNNLSKTRFRGLEYQLNYDAGVFYADLTYTHMIGKNEFCSNKAWL 721 Query: 610 NNLTYMLQSKNKET----GDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYD 665 + D S A + +VT G+ +K D Sbjct: 722 GGRLRYGDGSRRGNFYVEPDAASNDFVTCDGGTQFGSAAYLPGDRGSVTLGGRAFDRKLD 781 Query: 666 Y---------HGDRVTGSAN---DQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFR 713 + D S Y + L +Y+L+ +L+L V+NL ++ Sbjct: 782 AGVTVRFAPGYQDSSVPSNYPYLADWPKYTLFDLYASYKLTDSLTLRGSVENLTNRAYVV 841 Query: 714 AGNAQGVVGIDGAGAATYNEPGRTFYTSLTASF 746 + + GRT + F Sbjct: 842 SYGETLANTLGR---------GRTVQGGVEYRF 865 >3QLB-A nrPDB Length = 748 Score = 109 bits (272), Expect = 4e-24, Method: Composition-based stats. Identities = 128/742 (17%), Positives = 219/742 (29%), Gaps = 129/742 (17%) Query: 29 GDGSVIELGEQTVVATAQEETK----------------------QAPGVSIITAEDIAKR 66 + L + AT + + P + D Sbjct: 56 DQDHALTLDTSVISATQPDSATGPQAGYVAKRSLSGTKTDASLSEIPQSISVITRDQMDA 115 Query: 67 PPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRY 126 +++ +R GV ++S + + IRG T +L DG ++ + Sbjct: 116 QQVQSVNEALRYTAGVQANTTAASQRFD---TLSIRGFDVT-TGMLRDGLKGNTAQAWPK 171 Query: 127 GWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSV 186 V A +ERI+V++GPA+ +G + GGVVN I+K+ + + + Sbjct: 172 --------------VEAYGLERIDVLKGPASVLFGQNSPGGVVNQISKRPLDKPFHEVQI 217 Query: 187 YSNFPQHKAEGASERMSFGLNGPLTEN--LSYRVYGNIAKTDSD-----DWDINAGHESN 239 F +GPL + YR+ G + DS D + Sbjct: 218 QGGSFDRAQ------GQFDFSGPLDDEGQFLYRLVG--LERDSGTQFDHIKDDKQYFAPS 269 Query: 240 RTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFEAGFSRQGNIYTGDT--QNTNSN 297 T K +D G L + TL + N++ + N + Sbjct: 270 FTWKPNDDTSLTLLADYTQDTFGAPRVFLPAQGTLLGNPNGKVRHNVFLDEPGLDNDRTQ 329 Query: 298 NYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDP 357 + +L H N ++ S + G + ++ A G++ + Sbjct: 330 YSLGYLLEHRLNDVWSLNSSARY-GHVNLLTNTA-------------SGMSLAPDLRTLN 375 Query: 358 NNAGFYTATLRDLTAHGEVNLPLHLGYEQ-TLTLGSEWTEQK----LDDPSSNTQNTEEG 412 A + + +LG Q LG ++ + L S++ + Sbjct: 376 RAAYRFRIVGDTYSLDNNAQARWNLGSTQMVSLLGIDYRRTREDYYLRGGSASPIDIYNP 435 Query: 413 GSIPGLAGKNRSSSS-------SARIFSLFAEDNIELMPGTMLTPGLRWDHHDIVGDNWS 465 G S+ A ++A+ +LT G R D DN Sbjct: 436 VHHHHHHGGVFDPSTPFTNTVQRADQVGVYAQQQFTFDEHWVLTVGGRQDRSSARTDNRM 495 Query: 466 PSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDGLK 525 E+ T + G+ Y A N Y + Y K Sbjct: 496 NDSGSKQD-DEKFTYRTGLV--YLADNGLAPYISYSTSFDPVLGTNFYGTPY-------K 545 Query: 526 AETSVNKELGIEYSHDGLVA--GLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQW 583 ++ E+G++Y G+ + L+ F +N + A Sbjct: 546 PTSAKQSEVGVKYQPPGIDSYITLSLFDLTQENVL---------------TTDPAQRLNK 590 Query: 584 ENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNK-----ETGDVLSVTPRYTLNSM 638 + V G+E LA GL LTY +K E G + TP + Sbjct: 591 IQTGEINVRGIELEGKASLARGLDLLAALTYNDAEVSKSNNPLEKGKRPTDTPEKMASLW 650 Query: 639 LDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSP-YAIAGLGGTYRL---- 693 D+ + L G Y G +AN Q P Y + Y Sbjct: 651 ADY-TLPEGPLSGLGFGAG------VRYIGSTEADAANTQRVPSYTLLDAAVHYDFDKLI 703 Query: 694 --SKNLSLGAGVDNLFDKRLFR 713 +K L L NL DK + Sbjct: 704 PAAKGLRLAVNATNLTDKHYYE 725 >5FQ8-B nrPDB Length = 984 Score = 100 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 49/204 (24%), Positives = 81/204 (39%), Gaps = 19/204 (9%) Query: 35 ELGEQTVVATAQEETKQAPGVSIITA--EDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQ 92 ++ E V A + +++A G + + E IA+ S+ +S + + GV ++ S+S Sbjct: 22 QIDEVVVTAMGIKRSEKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQIS--STSSD 79 Query: 93 RGNNRQIDIRGM----GPENTLILVDGKPVSSRNSVRY-GWRGERDSRGDTNWVPADQVE 147 G + + IRG+ G L +VDG P+++ G D N + D V Sbjct: 80 PGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVA 139 Query: 148 RIEVIRGPAA-ARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGL 206 + +++G AA A YG+ AA GVV I TK E G L Sbjct: 140 NMTILKGAAATALYGSRAANGVVMITTKSGRKE--------KGVGIEYNGGVQWSTVLRL 191 Query: 207 NGPLTENLSYRVYGNIAKTDSDDW 230 GN + ++ W Sbjct: 192 P-EFQNEFGMGWNGNHTELENGSW 214 >4AIP-A nrPDB Length = 742 Score = 94.7 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 119/758 (15%), Positives = 224/758 (29%), Gaps = 119/758 (15%) Query: 39 QTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQ 98 TV + + +I+T + + D+ ++++ P ++ G G ++ Sbjct: 54 DTVTVKGDRQGSK-IRTNIVTLQQ-KDESTATDMRELLKEEPSIDF-----GGGNGTSQF 106 Query: 99 IDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAA 158 + +RGMG + I VD S+ G V V+ + V +G +A Sbjct: 107 LTLRGMGQNSVDIKVDNAYSDSQILYHQGRF----------IVDPALVKVVSVQKGAGSA 156 Query: 159 RYGNGAAGGVVNIITKQAGAETHG---NLSVYSNFPQHKAEGASERMSFGLNGPLTENLS 215 G GA G + T A G N V N G S S + + Sbjct: 157 SAGIGATNGAIIAKTVDAQDLLKGLDKNWGVRLNSGFASNNGVSYGASVF-----GKEGN 211 Query: 216 YRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLE 275 + + + D D++ G + GK + K + + Sbjct: 212 FDGLFSYNRNDEKDYEAGKGFRNVNGGKTVPYSALDKRSYLAKIGTTF----GDDDHRIV 267 Query: 276 FEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHE---TNRMYRETYSVTHRG-EWDFGSSLA 331 + I T + T + + + + + ++ + G F L Sbjct: 268 LSHMKDQHRGIRTVREEFTVGDKSSRINIDRQAPAYRETTQSNTNLAYTGKNLGFVEKLD 327 Query: 332 YLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLG 391 Y + + G G N T + L + L G Sbjct: 328 ANAYVLEKERYSADDSGTGYAGNVKGPNHTRITTRGANFNFDSR------LAEQTLLKYG 381 Query: 392 SEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNI---ELMPGT-- 446 + Q++ P + + + G+ ++ ED + +L T Sbjct: 382 INYRHQEIK-PQAFLNSKFSIPTTEEKNGQKVDKPMEQQMKDRADEDTVHAYKLSNPTKT 440 Query: 447 ---------------MLTPGLRWDHHDI--------VGDNWSPSLNLSHALTERVTLKAG 483 LT GLR+D + N +PS + E + A Sbjct: 441 DTGVYIEAIHDIGDFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSAS 500 Query: 484 IARAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGL 543 A ++P LY L + G+ DG KAE + N E+G Y+ Sbjct: 501 HNYASRSPRLYD-----ALQTHGKRGIISIA-------DGTKAERARNTEIGFNYNDGTF 548 Query: 544 VAGLTYFRNDYKNKIESGLSPVDHASGGKG-DYANAAIYQWENVPKAVVEGLEGTLTLPL 602 A +YF K+ + + + D + + + + +E GL + + Sbjct: 549 AANGSYFWQTIKDALANPQNRHDSVAVREAVNAGYIKNHGYELGASYRTGGLTAKVGVSH 608 Query: 603 ADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQAT-------DDLSLQATVTW 655 + + K+K +LS P + W A+ +L + W Sbjct: 609 SKP-------RFYDTHKDK----LLSANPEFGAQVGRTWTASLAYRFQNPNLEIG----W 653 Query: 656 YGKQKPKKYDY-----HGDRVTGSANDQLSPYAIAGLGGTYRL--SKNLSLGAGVDNLFD 708 G+ K DR N + + + ++ L++ V+N+F+ Sbjct: 654 RGRYVQKATGSILAAGQKDRKGNLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVNNVFN 713 Query: 709 KRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTASF 746 K + T GR + F Sbjct: 714 KFYYPHSQRWTN---------TLPGVGRDVRLGVNYKF 742 >6H7F-A nrPDB Length = 706 Score = 89.7 bits (220), Expect = 5e-18, Method: Composition-based stats. Identities = 116/748 (15%), Positives = 216/748 (28%), Gaps = 140/748 (18%) Query: 45 AQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTM-PGVNLTGNSSSGQRGNNRQIDIRG 103 ++ P +I + + + D++++I P + G S G + IRG Sbjct: 53 GSKKFLDTPFNTISYTDKYIEDKQAKDITEVIAATDPSIYTNGASG----GWSENYYIRG 108 Query: 104 MGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYG-- 161 + + G G + R+EV++GP+A G Sbjct: 109 YASS------------TNDMSMNGLFGITPFYRT----SPEMFGRVEVLKGPSALLNGMP 152 Query: 162 -NGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSYRVYG 220 G+ GG VN++TK A E L+ + EN + V Sbjct: 153 PAGSVGGTVNLVTKYAADEPFARLTTTYMSDAQFG------GHVDVGRRFGENKEFGVRI 206 Query: 221 NIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQT------- 273 N D G + ++ L W+ + Sbjct: 207 NGMYRD-------------------GDAAVNDQSKESRLFSLGLDWQGENARVFVDAYDA 247 Query: 274 LEFEAGFSRQGN--IYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDF-GSSL 330 L+ G +R N G + ++ + G + + RGE+DF + Sbjct: 248 LDHVDGVTRGVNVSTAVGIPKPPKADTLLSPDWG----SVETKDKGAMIRGEYDFSDQLM 303 Query: 331 AYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTLTL 390 AY Y ++ G + GT I T + G +T ++ Sbjct: 304 AYAAYGQSTTEYKYNGASAGT--ITSSTGTLSSTLGQLAFDVDKKSADAGFKGKFETGSV 361 Query: 391 GSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRS--------------------SSSSAR 430 +W ++TQ+ IPG + + S+ Sbjct: 362 KHQWVANATYY--NHTQDDYGYRIIPGFSDPVITNIYDPNPNWGPKPEFTPPFLFHSTLS 419 Query: 431 IFSLFAEDNIELM-PGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYK 489 S D + LT GLR H V S L T G+A K Sbjct: 420 TSSFGLADTLSFAQDKVQLTLGLR---HQTVKAT-SSVNTLPENAKSATTP--GVALLIK 473 Query: 490 APNLYQLNPDYLL-YSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLT 548 A + + +Y+ ++G +++ + + + +ELG++ L+ Sbjct: 474 ATDKISVYANYIEGLTKGDQAPATASN----PGEIFPPQKTKQQELGLKVDLGTFAHTLS 529 Query: 549 YFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKW 608 F P + K N + + + G+E + + ++ Sbjct: 530 AFEITK---------PSSYLDPSKL-VNNLPTFVSD--GEQRNRGIEWSFFGSPIEHVRL 577 Query: 609 SNNLTYMLQSKNK-----ETGDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYG--KQKP 661 TY+ K G P+ +W Q T+T G Sbjct: 578 MGGFTYLDPELTKTKSGGNDGHTAVAVPKNQAKLGAEWDTQ---VAQGTLTLSGNINAVS 634 Query: 662 KKYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKN---LSLGAGVDNLFDKRLFRAGNAQ 718 K+Y + ++ + +G Y ++ A + NL +K + Sbjct: 635 KQYINAENTLSVPGR------TLLDVGARYSTKVEDHPVTFRANIYNLTNKAYWAQPQLT 688 Query: 719 GVVGIDGAGAATYNEPGRTFYTSLTASF 746 + RT+ S++ F Sbjct: 689 NLALGAP----------RTYMLSVSYDF 706 >4B7O-A nrPDB Length = 745 Score = 87.0 bits (213), Expect = 3e-17, Method: Composition-based stats. Identities = 124/762 (16%), Positives = 225/762 (29%), Gaps = 124/762 (16%) Query: 39 QTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQ 98 TV + + +I+T + + D+ ++++ P ++ G G ++ Sbjct: 54 DTVTVKGDRQGSK-IRTNIVTLQQ-KDESTATDMRELLKEEPSIDF-----GGGNGTSQF 106 Query: 99 IDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAA 158 + +RGMG + I VD S+ G V V+ + V +G +A Sbjct: 107 LTLRGMGQNSVDIKVDNAYSDSQILYHQGRF----------IVDPALVKVVSVQKGAGSA 156 Query: 159 RYGNGAAGGVVNIITKQAGAETHG---NLSVYSNFPQHKAEGASERMSFGLNGPLTENLS 215 G GA G + T A G N V N EG S S + + Sbjct: 157 SAGIGATNGAIIAKTVDAQDLLKGLDKNWGVRLNSGFASNEGVSYGASVF-----GKEGN 211 Query: 216 YRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDID--GLLSWRLTPEQT 273 + + + D +++ G + GK + K G R+ Sbjct: 212 FDGLFSYNRNDEKEYEAGKGFRNFNGGKTVPYSALDKRSYLAKIGTTFGDGDHRIVLSHM 271 Query: 274 LEFEAGFSRQGNIYT-GDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLAY 332 + G +T GD + + T Y+ G + + AY Sbjct: 272 EDQHRGIRTVREEFTVGDASSRTNITRQAPPYRETTQSNTNLAYTGKDLGFVEKLDANAY 331 Query: 333 LQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLGS 392 + +K + G G N T + L + L G Sbjct: 332 VLEKK---RYSADDKDNGYAGNVVGPNHTRITTRGMNFNFDSR------LAEQTLLKYGI 382 Query: 393 EWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFS------------------- 433 + Q++ + E G + + + Sbjct: 383 NYRHQEIKPQAFLNGEFEISGKKKDPKDPKKEIDKTDEEKAKDKKDMDLVHSYKLSNPTK 442 Query: 434 ----LFAEDNIELMPGTMLTPGLRWDHHDI--------VGDNWSPSLNLSHALTERVTLK 481 + E I + G LT GLR+D + N +PS + E + Sbjct: 443 TDTGAYIE-AIHELDGFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFS 501 Query: 482 AGIARAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHD 541 + A ++P LY L + G+ DG KAE + N E+G Y+ Sbjct: 502 SSHNYASRSPRLYD-----ALQTHGKRGIISIA-------DGTKAERARNTEIGFNYNDG 549 Query: 542 GLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTL--- 598 A +YF K+ + + + + +AA+ + N G E Sbjct: 550 TFAANGSYFWQTIKDAL----------ANPQNRHVSAAVREAVNAGYIKNHGYELGASYR 599 Query: 599 TLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQAT-------DDLSLQA 651 T L + S++ + K+ +LS P + W A+ +L + Sbjct: 600 TGGLTAKVGVSHSKPRFYDTHPKK---LLSANPEFGAQVGRAWTASLAYRFQNPNLEIG- 655 Query: 652 TVTWYGKQKPKKYDY-----HGDRVTGSANDQLSPYAIAGLGGTYRL--SKNLSLGAGVD 704 W G+ K DR N + + + ++ L++ V+ Sbjct: 656 ---WRGRYVQKAVGSILVAGQKDRNGKLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVN 712 Query: 705 NLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTASF 746 N+F+ + T GR + F Sbjct: 713 NVFNTFYYPHSQRWTN---------TLPGVGRDVRLGVNYKF 745 >4RDT-A nrPDB Length = 748 Score = 84.3 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 95/624 (15%), Positives = 174/624 (27%), Gaps = 64/624 (10%) Query: 31 GSVIELGEQTVVATAQEETKQAPGVSIITAEDIAK----RPPSNDLSQIIRTMPGVNLTG 86 ++L +VV ++ + ++ I R + +L + +PG++ + Sbjct: 18 EQSVDLETVSVVGKSRPRATSGLLHTSTASDKIISGDTLRQKAVNLGDALDGVPGIHASQ 77 Query: 87 NSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQV 146 G IRG +L N S V Sbjct: 78 YG-----GGASAPVIRGQTGRRIKVL---------NHHGETGDMADFSPDHAIMVDTALS 123 Query: 147 ERIEVIRGPAAARYGNGAAGGVVN-----IITKQAGAETHGNLSVY-SNFPQHKAEGASE 200 +++E++RGP Y +G G+V+ I K G L + S+ K Sbjct: 124 QQVEILRGPVTLLYSSGNVAGLVDVADGKIPEKMPENGVSGELGLRLSSGNLEKLTSGGI 183 Query: 201 RMSFGLNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDI 260 + G N L YR G+ A + ++ G G +G Sbjct: 184 NIGLGKNFVLHTEGLYRKSGDYAVPRYRNLKRLPDSHADSQTGSIGLSWVGEKGFIGVAY 243 Query: 261 DGLLSWRLTPEQTLEFEAGFS-----------RQGNIYTGDTQNTNSNNYVKQMLGHETN 309 P + E++ + R +Y +Y L + Sbjct: 244 SDRRDQYGLPAHSHEYDDCHADIIWQKSLINKRYLQLYP-HLLTEEDIDYDNPGLSCGFH 302 Query: 310 RMYRETYSVTHRGEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAG-FYTATLR 368 ++ TH G + A + + Sbjct: 303 DD-DNAHAHTHSGRPWIDLRNKRYELRAEWKQPFPGFEALRVHLNRNDYRHDEKAGDAVE 361 Query: 369 DLTAHGEVNLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSS 428 + + N + L ++ L W Q L SS +I + + Sbjct: 362 NFFNNQTQNARIELRHQPIGRLKGSWGVQYLQQKSS------ALSAISEAVKQPMLLDNK 415 Query: 429 ARIFSLFAE-----DNIELMPGTMLT---PGLRWD----HHDIVGDNWSPSLNLSHALTE 476 + +S F DN L G + +++D + ++ P L Sbjct: 416 VQHYSFFGVEQANWDNFTLEGGVRVEKQKASIQYDKALIDRENYYNHPLPDLGAHRQTAR 475 Query: 477 RVTLKAGIARAYKAPNLYQLNPDYL-LYSRGQGCYGQ----STSCYLRGNDGLKAETSVN 531 L + + L + Q Y +T+ + GN L E S N Sbjct: 476 SFALSGNWY--FTPQHKLSLTASHQERLPSTQELYAHGKHVATNTFEVGNKHLNKERSNN 533 Query: 532 KELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVV 591 EL + Y D L +RN + N I + D + + ++ N A Sbjct: 534 IELALGYEGDRWQYNLALYRNRFGNYIYAQTLNDGRGPKSIEDDSEMKLVRY-NQSGADF 592 Query: 592 EGLEGTLTLPLADGLKWSNNLTYM 615 G EG + + + Y+ Sbjct: 593 YGAEGEIYFKPTPRYRIGVSGDYV 616 >3V8X-A nrPDB Length = 904 Score = 81.2 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 63/374 (16%), Positives = 119/374 (31%), Gaps = 59/374 (15%) Query: 411 EGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPGTMLTPGLRWDHHDIVGD-------- 462 G+ RS + + + DN+ L + GLR+D+ D Sbjct: 552 RLGNNTYTDCTPRSINGKSYYAA--VRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGT 609 Query: 463 --NWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRG 520 S + + T+ + L + ++ P+ ++ + + + Sbjct: 610 HRTLSWNAGIVLKPTDWLDLTYRTSTGFRLPSFAEMY-GWRAGVQSKAV----------- 657 Query: 521 NDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAI 580 + E S NKE GI + D ++F N Y++ I G A G Sbjct: 658 --KIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGY----EAQIKDGKEEAKGD 711 Query: 581 YQWENVPKAVVEGLEGTLTLPLA-------DGLKWSNNLTYMLQSKNKETGDVLSV---- 629 + N A + G+ + +G + + K+ D + Sbjct: 712 PAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVRVRDIKKRADRTDIQSHL 771 Query: 630 -----TPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSAND------Q 678 RY + D Q + +T+ ++ + + G++ + + Sbjct: 772 FDAIQPSRYVVGLGYD-QPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARR 830 Query: 679 LSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAAT------YN 732 P+ I + G Y + K+ +L AGV NL + R N + G Y Sbjct: 831 TRPWYIVDVSGYYTVKKHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYA 890 Query: 733 EPGRTFYTSLTASF 746 PGR + SL F Sbjct: 891 APGRNYTFSLEYKF 904 Score = 66.2 bits (159), Expect = 5e-11, Method: Composition-based stats. Identities = 34/158 (21%), Positives = 59/158 (37%), Gaps = 11/158 (6%) Query: 25 AAGQGDGSVIELGEQTVVATAQEETKQAPGV---SIITAEDIAKRPPSNDLSQIIRTMPG 81 AGQ +L V A Q+ + ++ + D + ++ + R PG Sbjct: 17 QAGQAQEK--QLDTIQVKAKKQKTRRDNEVTGLGKLVKSSDTLSKEQVLNIRDLTRYDPG 74 Query: 82 VNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDT--N 139 + + RG + IRGM + VDG + + G R + N Sbjct: 75 IAVVEQG----RGASSGYSIRGMDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGAIN 130 Query: 140 WVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAG 177 + + V+ +E+ +G + G+GA G V TK A Sbjct: 131 EIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTAD 168 >4ZGV-A nrPDB Length = 868 Score = 53.8 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 107/648 (16%), Positives = 205/648 (31%), Gaps = 103/648 (15%) Query: 21 NAVHAAGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSN-DLSQIIRTM 79 NA Q S E T++ T Q+ G+ II AE I K P N ++++++ Sbjct: 36 NAESEEEQQGDSSSGNSEDTILV-RSTPTSQSMGMQIINAEQIKKMPTGNGSVTELLKNN 94 Query: 80 PGVNLTGNSSSGQRGN---------------NRQIDIRGMGPENTLILVDGKPVSSRNSV 124 P V + +SS N + G+ N + ++ Sbjct: 95 PNVQFSNTASSSNIPGELAPENVSFHGEKFYNNNFMVDGLSNNNNINPGANNGELNQQPD 154 Query: 125 RYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAET-HGN 183 Y + W+ ++ +E +EV +A+YG GGVV+ T + G Sbjct: 155 GYSPADLPAGGPQSFWINSELIESLEVFDSNISAKYG-DFTGGVVDAKTMDPKLDKSSGK 213 Query: 184 LSVYSNFPQHKAEGASER---------------------MSFGLNGPLTENLSYRVYGNI 222 +S + SE S N PL++ + N Sbjct: 214 ISYRTTRDSWTKYHISEVISEEFYSGTNLYYQPKFKKHFYSATFNQPLSDKAGFIFAYNR 273 Query: 223 AKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEF-----E 277 ++D + ++ L G + DI ++ +P ++ + Sbjct: 274 QQSDIPYYHEYLQQWDDQERINETYLLKGTYLTDSGDI-IRMTGMYSPHESKFYKKDVKN 332 Query: 278 AGFSRQGNIYTGDTQNTNSNNYVKQ--MLGHETNRMYRETYSVTHRG--EWDFGSSLAYL 333 GF+ G Y + + ++ ++ K + G++ E + +++ + G + Sbjct: 333 GGFTNSGGGYRFNMEWEHNASWGKMTSLAGYQYTEDKTEHEADSYQTWRRFSSGFVSNVI 392 Query: 334 QYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLG-- 391 + + + GG G F N + F L E+N G + G Sbjct: 393 DWSSSGGANGQNSNIGG-YGSFATNTSSF------SLKQDYELNPVSWYGINHQIDFGWE 445 Query: 392 SEWTEQKLDDPSSNTQN---TEEGGSIPGL------AGKNRSSSSSARIFSLFAEDNIEL 442 +++ + S G+ G +R L+ E N+++ Sbjct: 446 TDFYTSRYRRFSDVYTGGVLVVPTGASAGSVVCQSGDELCIPGEQYSRTRILYPERNVQV 505 Query: 443 MP--------------GTMLTPGLR--WDHHDIVGDNWSPSLNLSHAL-TERVTLKAGIA 485 +TPG+R +D + N +P + S+ + +R T G A Sbjct: 506 SNVNYAAYLQNSMSYGRLEVTPGVRVSYDDF-LENLNIAPRFSASYDVFGDRSTRLFGGA 564 Query: 486 RAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVA 545 Y A N+ L Y QG + T+ G Y+ L Sbjct: 565 NRYYAGNI-------LAYKMRQGIGSNIQESRISPT---APWTTPTLRTGTNYNVSDLN- 613 Query: 546 GLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEG 593 Y +++ GLS ++ + N + ++G Sbjct: 614 ------TPYSDELSLGLSQRVMSTVWTAKWVNRQGKEQFGRETTTIDG 655 >1W99-A nrPDB Length = 558 Score = 33.0 bits (73), Expect = 0.48, Method: Composition-based stats. Identities = 40/252 (15%), Positives = 75/252 (29%), Gaps = 10/252 (3%) Query: 27 GQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTG 86 G I+L + + + + V+ + I ++ S I T G+ T Sbjct: 282 GSNLTHQIQLNSNVYKTSITDTSSPSNRVTKMDFYKI-DGTLASYNSNITPTPEGLRTTF 340 Query: 87 NSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQV 146 S Q + + I D +S D QV Sbjct: 341 FGFSTNENTPNQPTVNDYTHILSYIKTDVIDYNSNRVSFAWTHKIVDPNNQIYTDAITQV 400 Query: 147 ERIE--VIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSF 204 ++ + A G G GG + +T + ++ R+ + Sbjct: 401 PAVKSNFLNATAKVIKGPGHTGGDLVALTSNGTLSGRMEIQCKTSIFNDPTRSYGLRIRY 460 Query: 205 GLNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKD-IDGL 263 N P+ N+SY V +++ + + +N E R KD D + Sbjct: 461 AANSPIVLNVSY-VLQGVSRGTTISTESTFSRPNNIIPTDLK-----YEEFRYKDPFDAI 514 Query: 264 LSWRLTPEQTLE 275 + RL+ Q + Sbjct: 515 VPMRLSSNQLIT 526 >3W1J-A nrPDB Length = 392 Score = 31.5 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 9/77 (11%), Positives = 33/77 (42%), Gaps = 7/77 (9%) Query: 32 SVIELGEQTVVATA-------QEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNL 84 + + + T+ ++ + P + ++T ++ A R + L ++++ +PG+ + Sbjct: 252 RALRIDKLTLSGLEMTLKLYFEKRYEDIPVIRMLTQDEKALRQKAKRLEKLLKDIPGLKI 311 Query: 85 TGNSSSGQRGNNRQIDI 101 + + G ++ Sbjct: 312 SVIKDKAKPGGGSLPEL 328 >3W1H-A nrPDB Length = 452 Score = 31.5 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 9/77 (11%), Positives = 33/77 (42%), Gaps = 7/77 (9%) Query: 32 SVIELGEQTVVATA-------QEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNL 84 + + + T+ ++ + P + ++T ++ A R + L ++++ +PG+ + Sbjct: 312 RALRIDKLTLSGLEMTLKLYFEKRYEDIPVIRMLTQDEKALRQKAKRLEKLLKDIPGLKI 371 Query: 85 TGNSSSGQRGNNRQIDI 101 + + G ++ Sbjct: 372 SVIKDKAKPGGGSLPEL 388 >1KFW-A nrPDB Length = 435 Score = 30.0 bits (65), Expect = 4.1, Method: Composition-based stats. Identities = 18/138 (13%), Positives = 41/138 (29%), Gaps = 11/138 (7%) Query: 235 GHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFEAGFSR----QGNIYTGD 290 GH++N A ++ +K + L+ + P+Q A + R N+ Sbjct: 274 GHQANLYDDPADPRAPSKKFSADKAVKKYLAAGIDPKQLGLGLAAYGRGWTGAKNVSPWG 333 Query: 291 TQNTNS--NNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLAYLQYEKTRNSR-----I 343 + + + + Y W + + + + + Sbjct: 334 PATDGAPGTYETANEDYDKLKTLGTDHYDAATGSAWRYDGTQWWSYDNIATTKQKTDYIV 393 Query: 344 NEGLAGGTEGIFDPNNAG 361 ++GL GG + G Sbjct: 394 SKGLGGGMWWELSGDRNG 411 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.300 0.108 0.242 Lambda K H 0.267 0.0326 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,986,664 Number of Sequences: 36641 Number of extensions: 852951 Number of successful extensions: 1875 Number of sequences better than 10.0: 34 Number of HSP's better than 10.0 without gapping: 50 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 1615 Number of HSP's gapped (non-prelim): 102 length of query: 746 length of database: 10,336,785 effective HSP length: 104 effective length of query: 642 effective length of database: 6,526,121 effective search space: 4189769682 effective search space used: 4189769682 T: 11 A: 40 X1: 16 ( 6.9 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.4 bits) S2: 62 (28.8 bits)