BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q05085 (590 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5A2O-A nrPDB 1207 0.0 6EI3-A nrPDB 87 2e-17 2XUT-A nrPDB 77 2e-14 4Q65-A nrPDB 65 6e-11 4APS-A nrPDB 50 2e-06 4IKY-A nrPDB 47 3e-05 4W6V-A nrPDB 44 2e-04 6GS4-A nrPDB 41 0.002 2MCP-H nrPDB 30 2.0 >5A2O-A nrPDB Length = 590 Score = 1207 bits (3124), Expect = 0.0, Method: Compositional matrix adjust. Identities = 590/590 (100%), Positives = 590/590 (100%) Query: 1 MSLPETKSDDILLDAWDFQGRPADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLT 60 MSLPETKSDDILLDAWDFQGRPADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLT Sbjct: 1 MSLPETKSDDILLDAWDFQGRPADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLT 60 Query: 61 GTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLST 120 GTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLST Sbjct: 61 GTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLST 120 Query: 121 IIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEP 180 IIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEP Sbjct: 121 IIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEP 180 Query: 181 KERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTN 240 KERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTN Sbjct: 181 KERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTN 240 Query: 241 RYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTE 300 RYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTE Sbjct: 241 RYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTE 300 Query: 301 QFRSLDKAAIRDQEAGVTSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLT 360 QFRSLDKAAIRDQEAGVTSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLT Sbjct: 301 QFRSLDKAAIRDQEAGVTSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLT 360 Query: 361 TLSVAQSETLDRSIGSFEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPL 420 TLSVAQSETLDRSIGSFEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPL Sbjct: 361 TLSVAQSETLDRSIGSFEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPL 420 Query: 421 QRIGLGLFFGSMAMAVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIY 480 QRIGLGLFFGSMAMAVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIY Sbjct: 421 QRIGLGLFFGSMAMAVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIY 480 Query: 481 TGQLDFFLRECPKGMKGMSTGLLLSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGR 540 TGQLDFFLRECPKGMKGMSTGLLLSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGR Sbjct: 481 TGQLDFFLRECPKGMKGMSTGLLLSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGR 540 Query: 541 LYNFYWLVAVLVALNFLIFLVFSKWYVYKEKRLAEVGIELDDEPSIPMGH 590 LYNFYWLVAVLVALNFLIFLVFSKWYVYKEKRLAEVGIELDDEPSIPMGH Sbjct: 541 LYNFYWLVAVLVALNFLIFLVFSKWYVYKEKRLAEVGIELDDEPSIPMGH 590 >6EI3-A nrPDB Length = 514 Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 66/213 (30%), Positives = 101/213 (47%), Gaps = 33/213 (15%) Query: 37 ILCIEAVERLTTLGIGVNLVTYLTGTMHLG-------NATAANTVTNFLGTSFMLCLLGG 89 I+ EA ER + G+ LV +L ++ L +A A + + +F+ F LLGG Sbjct: 7 IIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGG 66 Query: 90 FIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVL 149 ++AD F G+Y TI F+ I G + L L + SG Sbjct: 67 WLADRFFGKYTTIIWFSLIYCAGHACLALFE------------------DSRSG-----F 103 Query: 150 YLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLAVTVLV 209 ++ L L A G GG+K V+ F DQFD++ K R+K+ F+ F++ IN GSL A ++ Sbjct: 104 FVGLGLIAFGAGGIKPLVASFMVDQFDQSN-KHRAKVV--FDAFYWIINFGSLFASLLIP 160 Query: 210 YVQDDVGRKWGYGICAFAIVLALSVFLAGTNRY 242 +G W +GI + +A +VF G RY Sbjct: 161 LALKHLGPSWAFGIPGILMFIATAVFWLGRKRY 193 >2XUT-A nrPDB Length = 524 Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 62/212 (29%), Positives = 89/212 (41%), Gaps = 32/212 (15%) Query: 37 ILCIEAVERLTTLGIGVNLVTYLTGTM------HLGNATAANTVTNFLGTSFMLCLLGGF 90 I+ EA ER + G+ L +L + L A A + +F+ + LLGG+ Sbjct: 17 IIASEACERFSFYGMRNILTPFLMTALLLSIPEELRGAVAKDVFHSFVIGVYFFPLLGGW 76 Query: 91 IADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVLY 150 IAD F G+Y TI + I G + L + H Q Y Sbjct: 77 IADRFFGKYNTILWLSLIYCVGHAFLAIF----------------EHSVQG-------FY 113 Query: 151 LALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLAVTVLVY 210 L+L ALG+GG+K VS F DQFD++ K F+ F+F IN GS A + Sbjct: 114 TGLFLIALGSGGIKPLVSSFMGDQFDQSNKSLAQKA---FDMFYFTINFGSFFASLSMPL 170 Query: 211 VQDDVGRKWGYGICAFAIVLALSVFLAGTNRY 242 + + G +GI + +A F G RY Sbjct: 171 LLKNFGAAVAFGIPGVLMFVATVFFWLGRKRY 202 >4Q65-A nrPDB Length = 493 Score = 65.5 bits (158), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 52/239 (21%), Positives = 102/239 (42%), Gaps = 27/239 (11%) Query: 37 ILCIEAVERLTTLGIGVNLVTYLTGTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFL 96 ++ ++ E + G+ L+ YLT + + A + + ++ +LGGF+AD L Sbjct: 14 VVALQIWEYFSFYGMRALLILYLTNQLKYNDTHAYELFSAYCSLVYVTPILGGFLADKVL 73 Query: 97 GRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLT 156 G + + + A + A G +L S I P + LYL+L + Sbjct: 74 GNRMAVMLGALLMAIGHVVLGASEIHP-----------------------SFLYLSLAII 110 Query: 157 ALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVG 216 G G K++VS + ++ T+P+ F+ + NVGS++A Y Q++ Sbjct: 111 VCGYGLFKSNVSCLLGELYEPTDPRRDGG----FSLMYAAGNVGSIIAPIACGYAQEEYS 166 Query: 217 RKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPS 275 G+G+ A ++ L +FL G + + + + + ++ W + L A P+ Sbjct: 167 WAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLVLLVATPA 225 >4APS-A nrPDB Length = 491 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 78/381 (20%), Positives = 143/381 (37%), Gaps = 97/381 (25%) Query: 24 DRSKT--GGWASAAMILCIEAVERLTTLGIGVNLVTYL-----TGTMHLGNATAANTVTN 76 D+ KT G + + E ER + G+ L+ Y+ TG +H+ ATAA+ + Sbjct: 3 DKGKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAI 62 Query: 77 FLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSS 136 + ++ +GGF+AD +G A+ GV I+ Sbjct: 63 YASMVYLSGTIGGFVADRIIGAR------PAVFWGGVLIML------------------G 98 Query: 137 HCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFC 196 H A + L+ ++ L +GTG +K +VS +DE + + + F+ F F Sbjct: 99 HIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAG----FSIFVFG 154 Query: 197 INVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVA 256 IN+G+ +A ++ Q+ G + + A + + L V+ G + Sbjct: 155 INLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKK--------------- 199 Query: 257 AVIVAAWRNRKLELPADPSYLYDVDDI-------------IAAEG--------SMKGKQK 295 DP YL D + +A G ++ G Sbjct: 200 --------------TLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNS 245 Query: 296 LPHTEQFRSLDKAAIRDQEAGVTSNVFNKWTLST--LTDVEEVKQIVRMLPIWATCILFW 353 LP ++ AI + W +S+ +T E ++ +V +P++ +LFW Sbjct: 246 LPAYINLLTIVAIAI--------PVFYFAWMISSVKVTSTEHLR-VVSYIPLFIAAVLFW 296 Query: 354 TVHAQLT-TLSVAQSETLDRS 373 + Q + L+ +E +D S Sbjct: 297 AIEEQGSVVLATFAAERVDSS 317 >4IKY-A nrPDB Length = 507 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 84/403 (20%), Positives = 157/403 (38%), Gaps = 57/403 (14%) Query: 41 EAVERLTTLGIGVNLVTYL-----TGTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTF 95 E ER + G+ LV Y+ G + L A ++ + +M ++GG++AD Sbjct: 32 EFWERFSYYGMRAILVYYMYYEVSKGGLGLDEHLALAIMSIYGALVYMSGIIGGWLADRV 91 Query: 96 LGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYL 155 G + A+F G+ I+ + H A + L++++ L Sbjct: 92 FGT--SRAVFYG----GLLIM------------------AGHIALAIPGGVAALFVSMAL 127 Query: 156 TALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDV 215 LGTG +K +VS D + + + + F+ F+ IN+G+ LA V+ Sbjct: 128 IVLGTGLLKPNVSSIVGDMYKPGDDRRDAG----FSIFYMGINLGAFLAPLVVGTAGMKY 183 Query: 216 GRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPS 275 G+G+ A + L L VF+A KK +G T V + A + + + A + Sbjct: 184 NFHLGFGLAAVGMFLGLVVFVATR-----KKNLGLAGTYVPNPLTPAEKKKAAAIMAVGA 238 Query: 276 YLYDV-DDIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAGVTSNVFNKWTLSTLTDVE 334 + V I+ G E F SL + + F S T E Sbjct: 239 VVIAVLLAILIPNGWFT-------VETFISL----VGILGIIIPIIYFVVMYRSPKTTAE 287 Query: 335 EVKQIVRMLPIWATCILFWTVHAQLTTLSVAQSETLDR-SIGSFEIPPASMAVFYVGGLL 393 E +++ +P++ +FW + Q +T+ ++ + + + PA ++ Sbjct: 288 ERSRVIAYIPLFVASAMFWAIQQQGSTILANYADKRTQLDVAGIHLSPAWFQSLNPLFII 347 Query: 394 LTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAMAV 436 + V+ + ++L K+ P Q+ LGL F ++ V Sbjct: 348 ILAPVFAWMWVKLGKRQPTIP------QKFALGLLFAGLSFIV 384 >4W6V-A nrPDB Length = 519 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 46/200 (23%), Positives = 80/200 (40%), Gaps = 31/200 (15%) Query: 41 EAVERLTTLGIGVNLVTYLTGT-----MHLGNATAANTVTNFLGTSFMLCLLGGFIADTF 95 E ER + GI L+ ++ T M L A+ V F G+ ++ L GG +AD + Sbjct: 27 EMWERFSFYGIRPLLILFMAATVFDGGMGLPREQASAIVGIFAGSMYLAALPGGLLADNW 86 Query: 96 LGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYL 155 LG+ + + + A G + LS + ++ L Sbjct: 87 LGQQRAVWYGSILIALGHLSIALSAFFGN----------------------DLFFIGLVF 124 Query: 156 TALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDV 215 LGTG K +S + + + F+ F+ IN+GS +A + ++ Sbjct: 125 IVLGTGLFKTCISVMVGTLYKPGDARRDGG----FSLFYMGINMGSFIAPLLSGWLLRTH 180 Query: 216 GRKWGYGICAFAIVLALSVF 235 G WG+GI +++AL +F Sbjct: 181 GWHWGFGIGGIGMLVALLIF 200 >6GS4-A nrPDB Length = 508 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 35/170 (20%), Positives = 69/170 (40%), Gaps = 27/170 (15%) Query: 36 MILCIEAVERLTTLGIGVNLVTYLTGTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTF 95 +I IE ER G+ + YL + + A + ++F + L +GG++ D Sbjct: 25 LIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKV 84 Query: 96 LGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYL 155 LG I + A + A G +++ SG ++Y+ + Sbjct: 85 LGTKRVIMLGAIVLAIGYALVAW-----------------------SGHDAGIVYMGMAA 121 Query: 156 TALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLAV 205 A+G G KA+ S S +++ +P+ F ++ +N+GS ++ Sbjct: 122 IAVGNGLFKANPSSLLSTCYEKNDPRLDGA----FTMYYMSVNIGSFFSM 167 >2MCP-H nrPDB Length = 222 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 18/49 (36%), Positives = 22/49 (44%) Query: 502 LLLSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGRLYNFYWLVAV 550 L LS GF FS + V + GK WIA NKG Y + +V Sbjct: 18 LRLSCATSGFTFSDFYMEWVRQPPGKRLEWIAASRNKGNKYTTEYSASV 66 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5A2O-A nrPDB 882 0.0 4IKY-A nrPDB 357 6e-99 4APS-A nrPDB 302 3e-82 4Q65-A nrPDB 256 1e-68 4W6V-A nrPDB 243 1e-64 2XUT-A nrPDB 229 2e-60 6EI3-A nrPDB 215 5e-56 6GS4-A nrPDB 201 9e-52 Sequences not found previously or not previously below threshold: 6GZ9-A nrPDB 215 4e-56 6JKD-A nrPDB 150 2e-36 3WDO-A nrPDB 39 0.007 4LDS-A nrPDB 38 0.013 6E9N-A nrPDB 30 3.1 3NA5-A nrPDB 29 5.6 2MCP-H nrPDB 29 5.9 1PW4-A nrPDB 29 6.1 6G9P-A nrPDB 29 8.1 >5A2O-A nrPDB Length = 590 Score = 882 bits (2278), Expect = 0.0, Method: Composition-based stats. Identities = 590/590 (100%), Positives = 590/590 (100%) Query: 1 MSLPETKSDDILLDAWDFQGRPADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLT 60 MSLPETKSDDILLDAWDFQGRPADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLT Sbjct: 1 MSLPETKSDDILLDAWDFQGRPADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLT 60 Query: 61 GTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLST 120 GTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLST Sbjct: 61 GTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLST 120 Query: 121 IIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEP 180 IIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEP Sbjct: 121 IIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEP 180 Query: 181 KERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTN 240 KERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTN Sbjct: 181 KERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTN 240 Query: 241 RYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTE 300 RYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTE Sbjct: 241 RYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTE 300 Query: 301 QFRSLDKAAIRDQEAGVTSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLT 360 QFRSLDKAAIRDQEAGVTSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLT Sbjct: 301 QFRSLDKAAIRDQEAGVTSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLT 360 Query: 361 TLSVAQSETLDRSIGSFEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPL 420 TLSVAQSETLDRSIGSFEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPL Sbjct: 361 TLSVAQSETLDRSIGSFEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPL 420 Query: 421 QRIGLGLFFGSMAMAVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIY 480 QRIGLGLFFGSMAMAVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIY Sbjct: 421 QRIGLGLFFGSMAMAVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIY 480 Query: 481 TGQLDFFLRECPKGMKGMSTGLLLSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGR 540 TGQLDFFLRECPKGMKGMSTGLLLSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGR Sbjct: 481 TGQLDFFLRECPKGMKGMSTGLLLSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGR 540 Query: 541 LYNFYWLVAVLVALNFLIFLVFSKWYVYKEKRLAEVGIELDDEPSIPMGH 590 LYNFYWLVAVLVALNFLIFLVFSKWYVYKEKRLAEVGIELDDEPSIPMGH Sbjct: 541 LYNFYWLVAVLVALNFLIFLVFSKWYVYKEKRLAEVGIELDDEPSIPMGH 590 >4IKY-A nrPDB Length = 507 Score = 357 bits (917), Expect = 6e-99, Method: Composition-based stats. Identities = 81/419 (19%), Positives = 153/419 (36%), Gaps = 57/419 (13%) Query: 25 RSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYL-----TGTMHLGNATAANTVTNFLG 79 R G + E ER + G+ LV Y+ G + L A ++ + Sbjct: 16 RGFFGHPKGLFTLFFTEFWERFSYYGMRAILVYYMYYEVSKGGLGLDEHLALAIMSIYGA 75 Query: 80 TSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCE 139 +M ++GG++AD G + + G L + Sbjct: 76 LVYMSGIIGGWLADRVFGTSRAVFYGGLLIMAGHIALAI--------------------- 114 Query: 140 QASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINV 199 + L++++ L LGTG +K +VS D + + + + F+ F+ IN+ Sbjct: 115 ---PGGVAALFVSMALIVLGTGLLKPNVSSIVGDMYKPGDDRRDAG----FSIFYMGINL 167 Query: 200 GSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVAAVI 259 G+ LA V+ G+G+ A + L L VF+A K +G T V + Sbjct: 168 GAFLAPLVVGTAGMKYNFHLGFGLAAVGMFLGLVVFVATRK-----KNLGLAGTYVPNPL 222 Query: 260 VAAWRNRKLELPADPSYLYDVD-DIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAGVT 318 A + + + A + + V I+ G E F SL + + Sbjct: 223 TPAEKKKAAAIMAVGAVVIAVLLAILIPNGWFT-------VETFISL----VGILGIIIP 271 Query: 319 SNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLTTLSVAQSETLDR-SIGSF 377 F S T EE +++ +P++ +FW + Q +T+ ++ + + Sbjct: 272 IIYFVVMYRSPKTTAEERSRVIAYIPLFVASAMFWAIQQQGSTILANYADKRTQLDVAGI 331 Query: 378 EIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAMAV 436 + PA +++ V+ + ++L K+ P Q+ LGL F ++ V Sbjct: 332 HLSPAWFQSLNPLFIIILAPVFAWMWVKLGKRQPTIP------QKFALGLLFAGLSFIV 384 >4APS-A nrPDB Length = 491 Score = 302 bits (773), Expect = 3e-82, Method: Composition-based stats. Identities = 99/507 (19%), Positives = 191/507 (37%), Gaps = 75/507 (14%) Query: 24 DRSKT--GGWASAAMILCIEAVERLTTLGIGVNLVTYL-----TGTMHLGNATAANTVTN 76 D+ KT G + + E ER + G+ L+ Y+ TG +H+ ATAA+ + Sbjct: 3 DKGKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAI 62 Query: 77 FLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSS 136 + ++ +GGF+AD +G + + G +L L Sbjct: 63 YASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLAL------------------ 104 Query: 137 HCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFC 196 + L+ ++ L +GTG +K +VS +DE + + + F+ F F Sbjct: 105 ------PFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAG----FSIFVFG 154 Query: 197 INVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVA 256 IN+G+ +A ++ Q+ G + + A + + L V+ G KK + + Sbjct: 155 INLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGG-----KKTLDPHYLRPT 209 Query: 257 AVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAG 316 + L S I ++ G LP ++ AI Sbjct: 210 DPLAPEEVKPLLVKV---SLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAI------ 260 Query: 317 VTSNVFNKWTLST--LTDVEEVKQIVRMLPIWATCILFWTVHAQLT-TLSVAQSETLDRS 373 + W +S+ +T E ++ +V +P++ +LFW + Q + L+ +E +D S Sbjct: 261 --PVFYFAWMISSVKVTSTEHLR-VVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSS 317 Query: 374 IGSFEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMA 433 P + ++L T + + K + P + +GL F ++ Sbjct: 318 ----WFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPT------KFAVGLMFAGLS 367 Query: 434 MAVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIYTGQLDFFLRECPK 493 + A+ +G + K PL L+ + +V +GE LI L + PK Sbjct: 368 FLLMAI-------PGALYGTSGKVSPL---WLVGSWALVILGEMLISPVGLSVTTKLAPK 417 Query: 494 GMKGMSTGLLLSTLALGFFFSSVLVTI 520 + + ++G ++ LVT+ Sbjct: 418 AFNSQMMSMWFLSSSVGSALNAQLVTL 444 >4Q65-A nrPDB Length = 493 Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats. Identities = 88/490 (17%), Positives = 186/490 (37%), Gaps = 65/490 (13%) Query: 30 GWASAAMILCIEAVERLTTLGIGVNLVTYLTGTMHLGNATAANTVTNFLGTSFMLCLLGG 89 + ++ ++ E + G+ L+ YLT + + A + + ++ +LGG Sbjct: 7 QPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYNDTHAYELFSAYCSLVYVTPILGG 66 Query: 90 FIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVL 149 F+AD LG + + + A + A G +L S I P + L Sbjct: 67 FLADKVLGNRMAVMLGALLMAIGHVVLGASEIHP-----------------------SFL 103 Query: 150 YLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLAVTVLV 209 YL+L + G G K++VS + ++ T+P+ F+ + NVGS++A Sbjct: 104 YLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGG----FSLMYAAGNVGSIIAPIACG 159 Query: 210 YVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVAAVIVAAWRNRKLE 269 Y Q++ G+G+ A ++ L +FL G + + + + + ++ W + Sbjct: 160 YAQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLVL 219 Query: 270 LPADPSYLYDVDDIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAGVTSNVFNKWTLST 329 L A P+ + ++ ++ + GV + ++ K Sbjct: 220 LVATPALI-----------TILFWKEWSVYALIVA------TIIGLGVLAKIYRK----- 257 Query: 330 LTDVEEVKQIVRMLPIWATCILFWTVHAQLTTLSVAQSET-LDRSIGSFEIPPASMAVFY 388 + ++ K++ ++ + +LFW Q + + ++R + + +P A Sbjct: 258 AENQKQRKELGLIVTLTFFSMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSIN 317 Query: 389 VGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAMAVAALVELKRLRTA 448 ++L V K+ +R + LGL S + L R Sbjct: 318 AFAVMLCGVFLAWVV----KESVAGNRTVRIWGKFALGLGLMSAGFCILTLS--ARWSAM 371 Query: 449 HAHGPTVKTLPLGFYLLIPQYLIVGIGEALIYTGQLDFFLRECPKGMKGMSTGL-LLSTL 507 + H +LP L++ ++G E I + R G+ G+ TG+ +L + Sbjct: 372 YGH----SSLP----LMVLGLAVMGFAELFIDPVAMSQITRIEIPGVTGVLTGIYMLLSG 423 Query: 508 ALGFFFSSVL 517 A+ + + V+ Sbjct: 424 AIANYLAGVI 433 >4W6V-A nrPDB Length = 519 Score = 243 bits (621), Expect = 1e-64, Method: Composition-based stats. Identities = 73/421 (17%), Positives = 151/421 (35%), Gaps = 46/421 (10%) Query: 22 PADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLT-----GTMHLGNATAANTVTN 76 P R+ G + + E ER + GI L+ ++ G M L A+ V Sbjct: 8 PGGRTFFGHPYPLSGLFLSEMWERFSFYGIRPLLILFMAATVFDGGMGLPREQASAIVGI 67 Query: 77 FLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSS 136 F G+ ++ L GG +AD +LG+ + + + A G + LS Sbjct: 68 FAGSMYLAALPGGLLADNWLGQQRAVWYGSILIALGHLSIALSAFFGN------------ 115 Query: 137 HCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFC 196 + ++ L LGTG K +S + + + F+ F+ Sbjct: 116 ----------DLFFIGLVFIVLGTGLFKTCISVMVGTLYKPGDARRDGG----FSLFYMG 161 Query: 197 INVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVA 256 IN+GS +A + ++ G WG+GI +++AL +F R + Sbjct: 162 INMGSFIAPLLSGWLLRTHGWHWGFGIGGIGMLVALLIF-------RGFAIPAMKRYDAE 214 Query: 257 AVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAG 316 + ++W + ++ + ++ ++ + +P + + A Sbjct: 215 VGLDSSWNKPTNQRQGVGRWVTAIMAVVVVIIALISQGVIP--INPVMIASLLVYVIAAS 272 Query: 317 VTSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFW-TVHAQLTTLSVAQSETLDRSIG 375 VT + + ++ + + +V + + + FW + T+ ++ ++ DR + Sbjct: 273 VTLYFIYLFAFAKMSRKDRARLLVCFI-LLVSAAFFWSAFEQKPTSFNLFANDYTDRMVM 331 Query: 376 SFEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAMA 435 FEIP ++L V+ L KK + + +G+ + A Sbjct: 332 GFEIPTVWFQSINALFIILLAPVFSWAWPALAKKKIQ----PSSITKFVIGILCAAAGFA 387 Query: 436 V 436 V Sbjct: 388 V 388 >2XUT-A nrPDB Length = 524 Score = 229 bits (585), Expect = 2e-60, Method: Composition-based stats. Identities = 103/476 (21%), Positives = 181/476 (38%), Gaps = 55/476 (11%) Query: 31 WASAAMILCIEAVERLTTLGIGVNLVTYLTGTM------HLGNATAANTVTNFLGTSFML 84 I+ EA ER + G+ L +L + L A A + +F+ + Sbjct: 11 PRQIPYIIASEACERFSFYGMRNILTPFLMTALLLSIPEELRGAVAKDVFHSFVIGVYFF 70 Query: 85 CLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGI 144 LLGG+IAD F G+Y TI + I G + L + Sbjct: 71 PLLGGWIADRFFGKYNTILWLSLIYCVGHAFLAIFE-----------------------H 107 Query: 145 QLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLA 204 + Y L+L ALG+GG+K VS F DQFD++ K F+ F+F IN GS A Sbjct: 108 SVQGFYTGLFLIALGSGGIKPLVSSFMGDQFDQSNKSLAQKA---FDMFYFTINFGSFFA 164 Query: 205 VTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVAAVIVAAWR 264 + + + G +GI + +A F G RY P + + R Sbjct: 165 SLSMPLLLKNFGAAVAFGIPGVLMFVATVFFWLGRKRYIHM----PPEPKDPHGFLPVIR 220 Query: 265 NRKLELPADPSYLYDVDDII---AAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAGVTSNV 321 + L + V +I +A ++ L + AG + + Sbjct: 221 SALLTKVEGKGNIGLVLALIGGVSAAYALVNIPTLGIVAGLCCAMVLVMGFVGAGASLQL 280 Query: 322 FNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLTTLSVAQSETLDRSIGSFEIPP 381 V+ V+ ++R+L ++A FW++ Q + + Q+ + + P Sbjct: 281 ERARKSHPDAAVDGVRSVLRILVLFALVTPFWSLFDQKASTWILQANDM---VKPQWFEP 337 Query: 382 ASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAMAVAALVE 441 A M ++L + V +++ L L+++G G+ ++ V ++ Sbjct: 338 AMMQALNPLLVMLLIPFNNFVLYPAIERM---GVKLTALRKMGAGIAITGLSWIVVGTIQ 394 Query: 442 LKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIYTGQLDFFLRECPKGMKG 497 L G + ++ F+ ++P Y ++ GE L+ L+F + PK MKG Sbjct: 395 LM------MDGGSALSI---FWQILP-YALLTFGEVLVSATGLEFAYSQAPKAMKG 440 >6GZ9-A nrPDB Length = 488 Score = 215 bits (548), Expect = 4e-56, Method: Composition-based stats. Identities = 91/545 (16%), Positives = 185/545 (33%), Gaps = 82/545 (15%) Query: 25 RSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYL-----TGTMHLGNATAANTVTNFLG 79 + G ++ +E ER + G+ L+ Y+ + + TA + ++ + Sbjct: 9 KGFFGHPRGLGVLFFVEFWERFSYYGMRAMLIFYMYFAIHQNGLGIDKTTAMSIMSVYGA 68 Query: 80 TSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCE 139 +M + G +IAD G + A + G L+L Sbjct: 69 LIYMSSIPGAWIADRITGTRGATLLGAVLIIIGHICLSL--------------------- 107 Query: 140 QASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINV 199 L L+ +++ +G+G +K ++S + E + + + F F+ +N+ Sbjct: 108 ---PFALFGLFSSMFFIIIGSGLMKPNISNIVGRLYPENDTRIDAG----FVIFYMSVNL 160 Query: 200 GSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVAAVI 259 G+L++ +L + D G+ + A + L L +L K +GS + + Sbjct: 161 GALISPIILQHFVDIRNFHGGFLLAAIGMALGLVWYLLFNR-----KNLGSVGMKPTNPL 215 Query: 260 VAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAGVTS 319 + + Y + I+A + HT F L + + Sbjct: 216 SKEEKRK---------YGMIIGIIVAIVIVVLLVTYYTHTLSF-DLISNTVLVLGVALPI 265 Query: 320 NVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLTTLSVAQS-ETLDRSIGSF- 377 F S E ++ +P++ +LFW++ Q + + E D + F Sbjct: 266 IYFTTMLRSKDVTDGERSRVKAFIPLFILGMLFWSIQEQGSNVLNIYGLERSDMQLNLFG 325 Query: 378 ---EIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAM 434 A +LL V + +++ KK + + +G ++ Sbjct: 326 WTTRFGEALFQSINPLFILLFAPVISMIWLKMGKKQPSLAI------KFSIGTLLAGLSY 379 Query: 435 AVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIYTGQLDFFLRECPKG 494 + LV L +G T +I Y+I IGE + ++ PK Sbjct: 380 ILIGLVGL-------GYGHT----QFSVNWVILSYVICVIGELCLSPTGNSAAVKLAPKA 428 Query: 495 MKGMSTGLLLSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGRLYNFYWLVAVLVAL 554 + L T A + LV +++ L + + F VA+++ L Sbjct: 429 FNAQMMSVWLLTNASAQAINGTLVKLIKP------------LGQTNYFIFLGTVAIVITL 476 Query: 555 NFLIF 559 L+F Sbjct: 477 IILVF 481 >6EI3-A nrPDB Length = 514 Score = 215 bits (547), Expect = 5e-56, Method: Composition-based stats. Identities = 107/492 (21%), Positives = 180/492 (36%), Gaps = 60/492 (12%) Query: 31 WASAAMILCIEAVERLTTLGIGVNLVTYLTGTMHLG-------NATAANTVTNFLGTSFM 83 I+ EA ER + G+ LV +L ++ L +A A + + +F+ F Sbjct: 1 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFF 60 Query: 84 LCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASG 143 LLGG++AD F G+Y TI F+ I G + L L Sbjct: 61 FPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFED---------------------- 98 Query: 144 IQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLL 203 + ++ L L A G GG+K V+ F DQFD++ F+ F++ IN GSL Sbjct: 99 -SRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHR---AKVVFDAFYWIINFGSLF 154 Query: 204 AVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVAAVIVAAW 263 A ++ +G W +GI + +A +VF G RY L AV+ +A Sbjct: 155 ASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSAL 214 Query: 264 RNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAGVTSNVFN 323 P ++ A + ++L + G + Sbjct: 215 LAHAPG-QGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLER 273 Query: 324 KWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLTTLSVAQSETLDRSIGSFEIPPAS 383 V+ V+ ++R+L I+A F+++ Q + V Q + PA Sbjct: 274 ARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRM--------PAW 325 Query: 384 M-----AVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAMAVAA 438 ++L + V L ++L P LR R+ G+ F +A Sbjct: 326 FTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLR---RMTSGIAFSGVAWIAVG 382 Query: 439 LVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIYTGQLDFFLRECPKGMKGM 498 +++ A G P+ I Y ++ GE L+ ++F + P MKG+ Sbjct: 383 AIQV-----AMDGGE-----PMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGV 432 Query: 499 STGLLLSTLALG 510 T +G Sbjct: 433 VMSFWYLTTTVG 444 >6GS4-A nrPDB Length = 508 Score = 201 bits (510), Expect = 9e-52, Method: Composition-based stats. Identities = 65/410 (15%), Positives = 139/410 (33%), Gaps = 59/410 (14%) Query: 30 GWASAAMILCIEAVERLTTLGIGVNLVTYLTGTMHLGNATAANTVTNFLGTSFMLCLLGG 89 + +I IE ER G+ + YL + + A + ++F + L +GG Sbjct: 19 QPKAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGG 78 Query: 90 FIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVL 149 ++ D LG I + A + A G +++ SG ++ Sbjct: 79 WLGDKVLGTKRVIMLGAIVLAIGYALVAW-----------------------SGHDAGIV 115 Query: 150 YLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLAVTVLV 209 Y+ + A+G G KA+ S S +++ +P+ F ++ +N+GS ++ Sbjct: 116 YMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGA----FTMYYMSVNIGSFFSMIATP 171 Query: 210 YVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVAAVIVAAWRNRKLE 269 ++ G + + +++ + F R+ K GS +RN L Sbjct: 172 WLAAKYGWSVAFALSVVGLLITIVNFAFCQ---RWVKQYGSK----PDFEPINYRNLLLT 224 Query: 270 LPADPSYLYDVDDIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAGVTSNVFNKWTLST 329 + V +IA + Q+ + + A+ G+ + Sbjct: 225 I-------IGVVALIAIATWLLHNQE---------VARMALGVVAFGIVVIFGKEAF--A 266 Query: 330 LTDVEEVKQIVRMLPIWATCILFWTVHAQLTTLSVAQSETLDRSIGSFEIPPASMAVFYV 389 + K IV + + I F T+L+ ++ SI + P Sbjct: 267 MKGAARRKMIVAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHSILGLAVEPEQYQALNP 326 Query: 390 GGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAMAVAAL 439 +++ + + + ++ L + +G+ S A + L Sbjct: 327 FWIIIGSPILAAIYNKMGDTLP-------MPTKFAIGMVMCSGAFLILPL 369 >6JKD-A nrPDB Length = 527 Score = 150 bits (378), Expect = 2e-36, Method: Composition-based stats. Identities = 70/490 (14%), Positives = 152/490 (31%), Gaps = 85/490 (17%) Query: 26 SKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLTGTMHLGNATAANTVTNFLGTSFMLC 85 SKT + + ++I E ER G+ +V ++ + ++ A + ++ Sbjct: 9 SKTHSFMTVSLI---ELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAALIYVSP 65 Query: 86 LLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGIQ 145 +GG++ D LG T+ + A I + G +++T+ T Sbjct: 66 AIGGWVGDKILGTKRTMLLGAGILSVGYALMTVPTENTW--------------------- 104 Query: 146 LTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLAV 205 ++ AL + +G G K + ++ + K S F ++ +NVGS ++ Sbjct: 105 --FMFSALGVIVVGNGLFKPNAGNLVRKIYEGDDSKIDSA----FTIYYMAVNVGSTFSM 158 Query: 206 TVLVYVQD--------DVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVAA 257 + +++D + G + +C I++ L G K L Sbjct: 159 LLTPWIKDYVNAQYGNEFGWHAAFAVCCVGILVGL-----GNYALMHKSLANYGSEPDTR 213 Query: 258 VIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAGV 317 + L L A + ++ + + + V Sbjct: 214 PVNKKSLAIVLALAALSVVASAI------------------ILEYEDVARVFVYAAGVAV 255 Query: 318 TSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLTTLSVAQSETL---DRSI 374 F+ S + E ++ L + + F+ + Q++T + D + Sbjct: 256 LGIFFHLIRTS---EPSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRNVDWDFQV 312 Query: 375 GSFEI---PPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGS 431 + PA +++ + V + ++ + LG + Sbjct: 313 FGTHLWTWSPAQFQALNPIWIMVLSPVLAWSYSWAGRNNKDFSIAA----KFALGFAVVA 368 Query: 432 MAMAVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIYTGQLDFFLREC 491 + + G +++I Y +GE L+ L R Sbjct: 369 IGFFIYGFA-----------GQFAVNGKTSSWVMIWGYASYSLGELLVSGLGLAMIARYV 417 Query: 492 PKGMKGMSTG 501 P M G G Sbjct: 418 PARMGGFMMG 427 >3WDO-A nrPDB Length = 453 Score = 38.6 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 62/373 (16%), Positives = 113/373 (30%), Gaps = 46/373 (12%) Query: 17 DFQGRPADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLTGTMHLGNATAANTVTN 76 D++ P +R T + + L + L TY A + Sbjct: 1 DYKMTPGERRAT---WGLGTVFSLRM---LGMFMVLPVLTTYGMALQGASEALIGIAIGI 54 Query: 77 FLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSS 136 + T + + G ++D GR I A+ A G I LS I G+ R Sbjct: 55 YGLTQAVFQIPFGLLSDRI-GRKPLIVGGLAVFAAGSVIAALSDSIWGIILGRALQ---- 109 Query: 137 HCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFC 196 G+G + A+V SD E + F F Sbjct: 110 ----------------------GSGAIAAAVMALLSDLTREQNRTK----AMAFIGVSFG 143 Query: 197 INVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSV-FLAGTNRYRFKKLIGSPMTQV 255 I +A+ + + +G + + A +++ N S M + Sbjct: 144 ITFA--IAMVLGPIITHKLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKG 201 Query: 256 A-AVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQE 314 + + ++A R KL ++ + +A G + P E ++ + Sbjct: 202 SFSKVLAEPRLLKLNFGIMCLHMLLMSTFVALPGQL-ADAGFPAAEHWKVYLATMLIAFG 260 Query: 315 AGVTSNVFNKWTLSTLTDVEEVKQ--IVRMLPIWATCILFW--TVHAQLTTLSVAQSETL 370 + V ++ + +V + +W FW V QL ++ E L Sbjct: 261 SVVPFIIYAEVKRKMKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEAL 320 Query: 371 DRSIGSFEIPPAS 383 S+ S E P Sbjct: 321 LPSLISKESPAGY 333 >4LDS-A nrPDB Length = 446 Score = 37.8 bits (86), Expect = 0.013, Method: Composition-based stats. Identities = 36/182 (19%), Positives = 62/182 (34%), Gaps = 31/182 (17%) Query: 56 VTYLTGTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSI 115 + ++ + L + T V++ L + + G +AD LGR + + A + G I Sbjct: 30 LLFIHKDIPLNSTTEGIVVSSMLIGAIVGAGSSGPLADK-LGRRRLVMLIAIVFIIGALI 88 Query: 116 LTLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQF 175 L ST L +L + + L GG ++V + S+ Sbjct: 89 LAAST------------------------NLALLIIGRLIIGLAVGGSMSTVPVYLSEM- 123 Query: 176 DETEPKERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVF 235 TE + + I +G L A V D G +W G+ V+ L Sbjct: 124 APTEYRGSLG-----SLNQLMITIGILAAYLVNYAFADIEGWRWMLGLAVVPSVILLVGI 178 Query: 236 LA 237 Sbjct: 179 YF 180 >6E9N-A nrPDB Length = 460 Score = 30.1 bits (66), Expect = 3.1, Method: Composition-based stats. Identities = 42/294 (14%), Positives = 80/294 (27%), Gaps = 51/294 (17%) Query: 62 TMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTI 121 + A + F + + GG+ D G +T I G S+ TL Sbjct: 60 EFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRV-GSRVT----YFIAIFGWSVATLFQG 114 Query: 122 IPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPK 181 + +A + + + F E E Sbjct: 115 FATGLMSLIGLRAITGIFEAPAF--------------------PTNNRMVTSWFPEHE-- 152 Query: 182 ERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGI-CAFAIVLALSVFLAGTN 240 S + ++ + F + + L ++ ++Q+ + W + + I+ +L F Sbjct: 153 RASAVGFYTSGQFVGL---AFLTPLLI-WIQEMLSWHWVFIVTGGIGIIWSLIWF----- 203 Query: 241 RYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTE 300 + +L+ D L D D + E K Sbjct: 204 -----------KVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLV 252 Query: 301 QFRSLDKAAIRDQEAGVTSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWT 354 R L + T F W + LT + K I + + T + F Sbjct: 253 FHRKLIGVYLGQFAVASTLWFFLTWFPNYLT---QEKGITALKAGFMTTVPFLA 303 Score = 28.9 bits (63), Expect = 6.9, Method: Composition-based stats. Identities = 35/181 (19%), Positives = 55/181 (30%), Gaps = 25/181 (13%) Query: 58 YLTGTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILT 117 YLT + A T +F+ LL G++AD + + Sbjct: 281 YLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRK------------------G 322 Query: 118 LSTIIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDE 177 S P C S+ A+ ++ + L A G + S Sbjct: 323 FSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSL--- 379 Query: 178 TEPKERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGY-GICAFAIVLALSVFL 236 P +T F F +G + V+ Y+ G I A A++ ALS L Sbjct: 380 -APMRLIGLTGG--VFNFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYIL 436 Query: 237 A 237 Sbjct: 437 L 437 >3NA5-A nrPDB Length = 570 Score = 28.9 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 3/58 (5%) Query: 377 FEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAM 434 F+ P VG L+++A+ DRV L +KL P G + GLF GS Sbjct: 357 FQHRPLWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKW---FVDGLFDGSFGF 411 >2MCP-H nrPDB Length = 222 Score = 28.9 bits (63), Expect = 5.9, Method: Composition-based stats. Identities = 21/63 (33%), Positives = 26/63 (41%) Query: 488 LRECPKGMKGMSTGLLLSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGRLYNFYWL 547 L E G+ L LS GF FS + V + GK WIA NKG Y + Sbjct: 4 LVESGGGLVQPGGSLRLSCATSGFTFSDFYMEWVRQPPGKRLEWIAASRNKGNKYTTEYS 63 Query: 548 VAV 550 +V Sbjct: 64 ASV 66 >1PW4-A nrPDB Length = 451 Score = 28.9 bits (63), Expect = 6.1, Method: Composition-based stats. Identities = 34/160 (21%), Positives = 54/160 (33%), Gaps = 30/160 (18%) Query: 86 LLGGFIADTFL-GRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGI 144 LL G+++D G +F T +I+ P NPT C G Sbjct: 306 LLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYW-------MNPAGNPTVDMICMIVIGF 358 Query: 145 QLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLA 204 ++Y + L L E PK+ + F F + GS+ A Sbjct: 359 ---LIYGPVMLIGLHA---------------LELAPKKAAGTAAGFTGLFGYLG-GSVAA 399 Query: 205 VTVLVYVQDDVGRKWGYGI---CAFAIVLALSVFLAGTNR 241 ++ Y D G G+ + + V+ L V + G R Sbjct: 400 SAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKR 439 >6G9P-A nrPDB Length = 582 Score = 28.5 bits (62), Expect = 8.1, Method: Composition-based stats. Identities = 35/236 (14%), Positives = 65/236 (27%), Gaps = 25/236 (10%) Query: 57 TYLTGTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSIL 116 YLT + L + GG +A T + + G+S Sbjct: 199 IYLTLDLKLQQYIETLLAGSRAAVVVTDPRTGGVLA-----LVSTPSYDPNLFVDGISSK 253 Query: 117 TLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFD 176 S ++ P N T AS ++ V ++AL G + + + FD Sbjct: 254 DYSALLNDPNTPLVNRATQGVYPPASTVKPYV-----AVSALSAGVITRN-----TTLFD 303 Query: 177 ETEPKERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFL 236 + + + + G L L D + Y + + Sbjct: 304 PGWWQLPGSEKRYRDWKKWG--HGRLNVTRSLEESADTFFYQVAYD-----MGIDRLSEW 356 Query: 237 AGTNRYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKG 292 G Y I + + W+ ++ + P Y D + +G Sbjct: 357 MGKFGYGHYTGIDLAEERSGNMPTREWKQKRFK---KPWYQGDTIPVGIGQGYWTA 409 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.322 0.130 0.354 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,140,348 Number of Sequences: 36641 Number of extensions: 811066 Number of successful extensions: 2670 Number of sequences better than 10.0: 38 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 2567 Number of HSP's gapped (non-prelim): 77 length of query: 590 length of database: 10,336,785 effective HSP length: 103 effective length of query: 487 effective length of database: 6,562,762 effective search space: 3196065094 effective search space used: 3196065094 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 62 (28.5 bits)