BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q03776 (544 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5ZWN-T nrPDB 1103 0.0 6G70-A nrPDB 81 1e-15 6G90-D nrPDB 71 1e-12 2OOE-A nrPDB 41 0.001 5WLC-LP nrPDB 36 0.037 5GMK-d nrPDB 33 0.25 5LJ5-S nrPDB 32 0.57 5A6B-D nrPDB 30 2.8 4EBA-A nrPDB 30 3.1 5XJC-J nrPDB 30 3.4 2OND-A nrPDB 30 3.6 >5ZWN-T nrPDB Length = 544 Score = 1103 bits (2854), Expect = 0.0, Method: Compositional matrix adjust. Identities = 544/544 (100%), Positives = 544/544 (100%) Query: 1 MDKYTALIHDENFSTLTLNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTY 60 MDKYTALIHDENFSTLTLNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTY Sbjct: 1 MDKYTALIHDENFSTLTLNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTY 60 Query: 61 SSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVI 120 SSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVI Sbjct: 61 SSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVI 120 Query: 121 SHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFS 180 SHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFS Sbjct: 121 SHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFS 180 Query: 181 KFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEM 240 KFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEM Sbjct: 181 KFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEM 240 Query: 241 YMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQ 300 YMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQ Sbjct: 241 YMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQ 300 Query: 301 RALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNE 360 RALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNE Sbjct: 301 RALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNE 360 Query: 361 YVLLRNLLEKIESSYSDNVENVDDFEIFWDYLQFKTFCQNSLYSSRYSDSQSNGLLNKEL 420 YVLLRNLLEKIESSYSDNVENVDDFEIFWDYLQFKTFCQNSLYSSRYSDSQSNGLLNKEL Sbjct: 361 YVLLRNLLEKIESSYSDNVENVDDFEIFWDYLQFKTFCQNSLYSSRYSDSQSNGLLNKEL 420 Query: 421 FDKVWKRLSCKEKKSGQEILLNNLVQFYSKDTVEFVEKNIFQKIIEFGWEYYLQNGMFWN 480 FDKVWKRLSCKEKKSGQEILLNNLVQFYSKDTVEFVEKNIFQKIIEFGWEYYLQNGMFWN Sbjct: 421 FDKVWKRLSCKEKKSGQEILLNNLVQFYSKDTVEFVEKNIFQKIIEFGWEYYLQNGMFWN 480 Query: 481 CYCRLIYFDTSRSYLDKRQYIVRKIWPQIDKKFAQSVLPSLTEFCESYFPEEMDTLEEMF 540 CYCRLIYFDTSRSYLDKRQYIVRKIWPQIDKKFAQSVLPSLTEFCESYFPEEMDTLEEMF Sbjct: 481 CYCRLIYFDTSRSYLDKRQYIVRKIWPQIDKKFAQSVLPSLTEFCESYFPEEMDTLEEMF 540 Query: 541 TEEP 544 TEEP Sbjct: 541 TEEP 544 >6G70-A nrPDB Length = 670 Score = 81.3 bits (199), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 82/369 (22%), Positives = 154/369 (41%), Gaps = 61/369 (16%) Query: 20 VSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFAL 79 V P+ W LL Y+ + + L R + +PY Y+ +A Sbjct: 91 VEMNPQDFTGWVYLLQYVEQENH----------LMAARKAFDKFFVHYPYCYGYWKKYAD 140 Query: 80 LEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQ-----LFKKYETAE 134 LE + N+ S ++++RGLQA S+ LW Y+ F + Q + +E A Sbjct: 141 LEKRHDNIKQSDEVYRRGLQAI-PLSVDLWIHYINFLKETLDPGDQETNTTIRGTFEHAV 199 Query: 135 EYVGLHFFSGEFWDLYL----EQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRI 190 G F S + W++Y+ EQ + R ++ V +IL IP +S + + + + Sbjct: 200 LAAGTDFRSDKLWEMYINWENEQGNLREVTA-----VYDRILGIPTQLYSHHFQRFKEHV 254 Query: 191 D-----DIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQ 245 D++ +Q QL ++L +SG GP D ++ IT ++ + Sbjct: 255 QNNLPRDLLTGEQFIQLR------RELASVNGHSGDDGPPGDDLPSGIEDITDPAKLITE 308 Query: 246 -----YQVLEIYS--------------IFESKIYINYY-TSPETLVSSDEIETWIKYLDY 285 ++++EI+ FE I Y+ P + +++ W +YL++ Sbjct: 309 IENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRPYFHVKP---LEKAQLKNWKEYLEF 365 Query: 286 TITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKT 345 I T + F+R ++ A Y+ WIKY+K++ N + + G ++V L K Sbjct: 366 EIENGTHERVVVLFERCVISCALYEEFWIKYAKYMEN--HSIEGVRHVFSRACTVHLPKK 423 Query: 346 EIIKLLYSV 354 + +L++ Sbjct: 424 PMAHMLWAA 432 >6G90-D nrPDB Length = 629 Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 66/270 (24%), Positives = 121/270 (44%), Gaps = 61/270 (22%) Query: 63 MLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLK-FCNNVIS 121 +L ++P L ++ FA +EY+L + S + ++ F SL LW YL C N + Sbjct: 80 ILRKYPLLFGFWKRFATIEYQLFGLKKSIAVLATSVKWF-PTSLELWCDYLNVLCVNNPN 138 Query: 122 HQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRK----ILEIPLH 177 + +E A++ +G F S FWD ++E +K W+ +++ I+E+PLH Sbjct: 139 ETDFIRNNFEIAKDLIGKQFLSHPFWDKFIE-----FEVGQKNWHNVQRIYEYIIEVPLH 193 Query: 178 SFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKIT 237 +++F+ + + +++ K L + D +L+K + +N Sbjct: 194 QYARFFTSYKKFLNE----KNLKTTRNIDIVLRKTQTTVN-------------------- 229 Query: 238 KEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHL 297 EI+ FESKI ++ + L +D++E W +YL + TD L Sbjct: 230 ------------EIWQ-FESKIKQPFFNLGQVL--NDDLENWSRYLKFV----TDPSKSL 270 Query: 298 N-------FQRALLPLAHYDLVWIKYSKWL 320 + F R L+P +++ W+ Y KWL Sbjct: 271 DKEFVMSVFDRCLIPCLYHENTWMMYIKWL 300 >2OOE-A nrPDB Length = 530 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 77/390 (19%), Positives = 169/390 (43%), Gaps = 54/390 (13%) Query: 36 YIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQ 95 Y + A + + + + Q + R TY ++ +FP ++ + E K N K+FQ Sbjct: 11 YDLDAWSILIREAQNQPIDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQ 70 Query: 96 RGLQAFNQRSLLLWTSYLKFC----NNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYL 151 R L + LW YL + + S+++++ + Y+ A + +G+ S + W Y+ Sbjct: 71 RCLMKVLH--IDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIWVDYI 128 Query: 152 EQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKK 211 N L+ + + ++ + QRI + +++ Q + ++ Sbjct: 129 --------------NFLKGVEAVGSYAEN-------QRITAV---RRVYQRGCVNPMINI 164 Query: 212 LKIDINYSG-RKGPYLQDAKKKLKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSP--E 268 ++ +Y+ +G + AKK ++ +++ YM + +V + Y + N + P Sbjct: 165 EQLWRDYNKYEEGINIHLAKKMIEDRSRD-YMNAR-RVAKEYETVMKGLDRNAPSVPPQN 222 Query: 269 TLVSSDEIETWIKYLDY--TITLQTDSLTHLN------FQRALLPLAHYDLVWIKYSKWL 320 T + +++ W KY+ + + L+T+ T + +++ LL L H+ +W + +++L Sbjct: 223 TPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYL 282 Query: 321 INSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLN--------EYVLLRNLLEKIE 372 S + LL K + FS + I + S + K N +Y R EK+ Sbjct: 283 EQS-SKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVH 341 Query: 373 SSYSD--NVENVDDFEIFWDYLQFKTFCQN 400 S Y+ +E++D ++ Y++F + Sbjct: 342 SIYNRLLAIEDIDPTLVYIQYMKFARRAEG 371 >5WLC-LP nrPDB Length = 440 Score = 36.2 bits (82), Expect = 0.037, Method: Compositional matrix adjust. Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 9/103 (8%) Query: 20 VSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFAL 79 +++P+ L +W LNY+ KA K I Y+ +L P + +I A Sbjct: 100 TNKFPQDLKFWAMYLNYM-KARG------NQTSYKKIHNIYNQLLKLHPTNVDIWISCAK 152 Query: 80 LEYKL-GNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVIS 121 EY++ N IFQ GL+ FN LW Y+KF N I+ Sbjct: 153 YEYEVHANFKSCRNIFQNGLR-FNPDVPKLWYEYVKFELNFIT 194 >5GMK-d nrPDB Length = 687 Score = 33.5 bits (75), Expect = 0.25, Method: Compositional matrix adjust. Identities = 40/176 (22%), Positives = 72/176 (40%), Gaps = 50/176 (28%) Query: 192 DIMDLKQLSQ-----LTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQY 246 DI+DL++L + T + LK+ ++D+ G +++ A+ + + Q+ Sbjct: 36 DILDLEELREYQRRKRTEYEGYLKRNRLDM------GQWIRYAQ----------FEIEQH 79 Query: 247 QVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPL 306 + SIFE + LV S I WI+Y+D + ++ + RA+ L Sbjct: 80 DMRRARSIFERAL----------LVDSSFIPLWIRYIDAELKVKCINHARNLMNRAISTL 129 Query: 307 AHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNEYV 362 D +W KY + ++ SL EI++ LY+ C L V Sbjct: 130 PRVDKLWYKY-------------------LIVEESLNNVEIVRSLYTKWCSLEPGV 166 >5LJ5-S nrPDB Length = 687 Score = 32.3 bits (72), Expect = 0.57, Method: Compositional matrix adjust. Identities = 40/176 (22%), Positives = 72/176 (40%), Gaps = 50/176 (28%) Query: 192 DIMDLKQLSQ-----LTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQY 246 DI+DL++L + T + LK+ ++D+ G +++ A+ + + Q+ Sbjct: 36 DILDLEELREYQRRKRTEYEGYLKRNRLDM------GQWIRYAQ----------FEIEQH 79 Query: 247 QVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPL 306 + SIFE + LV S I WI+Y+D + ++ + RA+ L Sbjct: 80 DMRRARSIFERAL----------LVDSSFIPLWIRYIDAELKVKCINHARNLMNRAISTL 129 Query: 307 AHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNEYV 362 D +W KY + ++ SL EI++ LY+ C L V Sbjct: 130 PRVDKLWYKY-------------------LIVEESLNNVEIVRSLYTKWCSLEPGV 166 >5A6B-D nrPDB Length = 648 Score = 30.0 bits (66), Expect = 2.8, Method: Compositional matrix adjust. Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 26/122 (21%) Query: 237 TKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTH 296 T E+YM YQ+ E + Y Y+ + EIE + + D T +L H Sbjct: 140 TFELYMEDTYQI-------EGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAH 192 Query: 297 LNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVIC 356 L+ + KW + +L +++LL+G + K ++I +++ + Sbjct: 193 LS----------------AFVKWGVKEVQELRDVEDILLIGEE---KVYDLIDGMFATLS 233 Query: 357 KL 358 KL Sbjct: 234 KL 235 >4EBA-A nrPDB Length = 645 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Query: 24 PKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSML-NEFPYLENYYIDFALLEY 82 PKS+ +W + L+++ + P+ K E Q ++ IR Y ++L LE+ + + E Sbjct: 148 PKSIQFWNEYLHFL-EHWKPVNKFEEQQRVQYIRKLYKTLLCQPMDCLESMWQRYTQWEQ 206 Query: 83 KLGNVSMSHKIFQRGLQAFNQRSL 106 + ++ I + Q N RSL Sbjct: 207 DVNQLTARRHIGELSAQYMNARSL 230 >5XJC-J nrPDB Length = 848 Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust. Identities = 14/59 (23%), Positives = 29/59 (49%), Gaps = 2/59 (3%) Query: 57 RCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKF 115 R + + P + ++ + +E LGNV+ + ++F+R ++ Q W SY+ F Sbjct: 296 RNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEW--QPEEQAWHSYINF 352 >2OND-A nrPDB Length = 308 Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust. Identities = 33/150 (22%), Positives = 68/150 (45%), Gaps = 19/150 (12%) Query: 269 TLVSSDEIETWIKYLDY--TITLQTDSLTHLN------FQRALLPLAHYDLVWIKYSKWL 320 T + +++ W KY+ + + L+T+ T + +++ LL L H+ +W + +++L Sbjct: 1 TPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYL 60 Query: 321 INSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLN--------EYVLLRNLLEKIE 372 S + LL K + FS + I + S + K N +Y R EK+ Sbjct: 61 EQS-SKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVH 119 Query: 373 SSYSD--NVENVDDFEIFWDYLQFKTFCQN 400 S Y+ +E++D ++ Y++F + Sbjct: 120 SIYNRLLAIEDIDPTLVYIQYMKFARRAEG 149 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5ZWN-T nrPDB 798 0.0 2OOE-A nrPDB 362 e-100 6G70-A nrPDB 353 9e-98 6G90-D nrPDB 222 4e-58 Sequences not found previously or not previously below threshold: 2OND-A nrPDB 159 3e-39 5XJC-J nrPDB 66 3e-11 5CTQ-A nrPDB 64 2e-10 5JPZ-A nrPDB 63 3e-10 5JJX-A nrPDB 61 2e-09 4EBA-A nrPDB 56 3e-08 5LJ5-S nrPDB 47 2e-05 6AHD-N nrPDB 46 3e-05 2UY1-A nrPDB 43 3e-04 5WLC-LP nrPDB 42 7e-04 5JJW-A nrPDB 41 0.001 5CTR-A nrPDB 41 0.001 3JB9-R nrPDB 37 0.014 3JCM-G nrPDB 36 0.043 5GMK-d nrPDB 36 0.053 6ICZ-I nrPDB 34 0.15 5MQ0-T nrPDB 31 1.2 3STO-A nrPDB 31 2.0 4AEZ-C nrPDB 30 2.2 4PFU-A nrPDB 29 4.7 3NYZ-A nrPDB 29 5.3 4K8X-A nrPDB 29 5.6 4JB7-A nrPDB 29 7.1 2CFA-B nrPDB 29 7.8 >5ZWN-T nrPDB Length = 544 Score = 798 bits (2060), Expect = 0.0, Method: Composition-based stats. Identities = 544/544 (100%), Positives = 544/544 (100%) Query: 1 MDKYTALIHDENFSTLTLNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTY 60 MDKYTALIHDENFSTLTLNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTY Sbjct: 1 MDKYTALIHDENFSTLTLNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTY 60 Query: 61 SSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVI 120 SSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVI Sbjct: 61 SSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVI 120 Query: 121 SHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFS 180 SHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFS Sbjct: 121 SHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFS 180 Query: 181 KFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEM 240 KFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEM Sbjct: 181 KFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEM 240 Query: 241 YMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQ 300 YMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQ Sbjct: 241 YMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQ 300 Query: 301 RALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNE 360 RALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNE Sbjct: 301 RALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNE 360 Query: 361 YVLLRNLLEKIESSYSDNVENVDDFEIFWDYLQFKTFCQNSLYSSRYSDSQSNGLLNKEL 420 YVLLRNLLEKIESSYSDNVENVDDFEIFWDYLQFKTFCQNSLYSSRYSDSQSNGLLNKEL Sbjct: 361 YVLLRNLLEKIESSYSDNVENVDDFEIFWDYLQFKTFCQNSLYSSRYSDSQSNGLLNKEL 420 Query: 421 FDKVWKRLSCKEKKSGQEILLNNLVQFYSKDTVEFVEKNIFQKIIEFGWEYYLQNGMFWN 480 FDKVWKRLSCKEKKSGQEILLNNLVQFYSKDTVEFVEKNIFQKIIEFGWEYYLQNGMFWN Sbjct: 421 FDKVWKRLSCKEKKSGQEILLNNLVQFYSKDTVEFVEKNIFQKIIEFGWEYYLQNGMFWN 480 Query: 481 CYCRLIYFDTSRSYLDKRQYIVRKIWPQIDKKFAQSVLPSLTEFCESYFPEEMDTLEEMF 540 CYCRLIYFDTSRSYLDKRQYIVRKIWPQIDKKFAQSVLPSLTEFCESYFPEEMDTLEEMF Sbjct: 481 CYCRLIYFDTSRSYLDKRQYIVRKIWPQIDKKFAQSVLPSLTEFCESYFPEEMDTLEEMF 540 Query: 541 TEEP 544 TEEP Sbjct: 541 TEEP 544 >2OOE-A nrPDB Length = 530 Score = 362 bits (928), Expect = e-100, Method: Composition-based stats. Identities = 77/390 (19%), Positives = 168/390 (43%), Gaps = 54/390 (13%) Query: 36 YIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQ 95 Y + A + + + + Q + R TY ++ +FP ++ + E K N K+FQ Sbjct: 11 YDLDAWSILIREAQNQPIDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQ 70 Query: 96 RGLQAFNQRSLLLWTSYLKFC----NNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYL 151 R L + LW YL + + S+++++ + Y+ A + +G+ S + W Y+ Sbjct: 71 RCLMKVLH--IDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIWVDYI 128 Query: 152 EQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKK 211 N L+ + + ++ + QRI + +++ Q + ++ Sbjct: 129 --------------NFLKGVEAVGSYAEN-------QRITAV---RRVYQRGCVNPMINI 164 Query: 212 LKIDINYSG-RKGPYLQDAKKKLKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSP--E 268 ++ +Y+ +G + AKK ++ +++ YM + +V + Y + N + P Sbjct: 165 EQLWRDYNKYEEGINIHLAKKMIEDRSRD-YMNAR-RVAKEYETVMKGLDRNAPSVPPQN 222 Query: 269 TLVSSDEIETWIKYLDYT--ITLQTDSLTHLN------FQRALLPLAHYDLVWIKYSKWL 320 T + +++ W KY+ + L+T+ T + +++ LL L H+ +W + +++L Sbjct: 223 TPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYL 282 Query: 321 INSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLN--------EYVLLRNLLEKIE 372 S + LL K + FS + I + S + K N +Y R EK+ Sbjct: 283 EQS-SKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVH 341 Query: 373 SSYSD--NVENVDDFEIFWDYLQFKTFCQN 400 S Y+ +E++D ++ Y++F + Sbjct: 342 SIYNRLLAIEDIDPTLVYIQYMKFARRAEG 371 Score = 29.0 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 43/319 (13%), Positives = 101/319 (31%), Gaps = 40/319 (12%) Query: 37 IVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQR 96 I + K E + L + ++ ++ + L + S Sbjct: 164 IEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPSVPPQNT 223 Query: 97 GLQAFNQRSLLLWTSYLKFCNNVISHQK-------QLFKKYETAEEYVGLHFFSGEFW-- 147 +A + + +W Y+++ + + ++ YE +G H + W Sbjct: 224 PQEA---QQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHH---PDIWYE 277 Query: 148 -DLYLEQ----------ISSRCTSSKKYWNVLRKILEIPL-------HSFSKFYALWLQR 189 YLEQ +++ S + N+ + + L +++ + ++ Sbjct: 278 AAQYLEQSSKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKY 337 Query: 190 IDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDA--KKKLKKITKEMYMVVQYQ 247 +L + D L ++ +G KK + ++ V Sbjct: 338 EKVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDARTRHHVYVTAA 397 Query: 248 VLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLA 307 ++E Y + + + D E + Y+DY L D+ T + F+R L + Sbjct: 398 LMEYYCSKDKSVAFKIFELG-LKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGS 456 Query: 308 HYD----LVWIKYSKWLIN 322 +W ++ + N Sbjct: 457 LPPEKSGEIWARFLAFESN 475 >6G70-A nrPDB Length = 670 Score = 353 bits (906), Expect = 9e-98, Method: Composition-based stats. Identities = 82/376 (21%), Positives = 154/376 (40%), Gaps = 59/376 (15%) Query: 13 FSTLTLNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLEN 72 F V P+ W LL Y+ + + L R + +PY Sbjct: 84 FEKFWKTVEMNPQDFTGWVYLLQYVEQENH----------LMAARKAFDKFFVHYPYCYG 133 Query: 73 YYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQ-----LF 127 Y+ +A LE + N+ S ++++RGLQA S+ LW Y+ F + Q + Sbjct: 134 YWKKYADLEKRHDNIKQSDEVYRRGLQAI-PLSVDLWIHYINFLKETLDPGDQETNTTIR 192 Query: 128 KKYETAEEYVGLHFFSGEFWDLYL----EQISSRCTSSKKYWNVLRKILEIPLHSFSKFY 183 +E A G F S + W++Y+ EQ + R ++ V +IL IP +S + Sbjct: 193 GTFEHAVLAAGTDFRSDKLWEMYINWENEQGNLREVTA-----VYDRILGIPTQLYSHHF 247 Query: 184 ALWLQRID-----DIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITK 238 + + + D++ +Q QL ++L +SG GP D ++ IT Sbjct: 248 QRFKEHVQNNLPRDLLTGEQFIQLR------RELASVNGHSGDDGPPGDDLPSGIEDITD 301 Query: 239 EMYMVV-----QYQVLEIYS--------------IFESKIYINYYTSPETLVSSDEIETW 279 ++ +++++EI+ FE I Y+ + +++ W Sbjct: 302 PAKLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRPYFHV--KPLEKAQLKNW 359 Query: 280 IKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLK 339 +YL++ I T + F+R ++ A Y+ WIKY+K++ N + + G ++V Sbjct: 360 KEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMEN--HSIEGVRHVFSRACT 417 Query: 340 FSLKKTEIIKLLYSVI 355 L K + +L++ Sbjct: 418 VHLPKKPMAHMLWAAF 433 >6G90-D nrPDB Length = 629 Score = 222 bits (565), Expect = 4e-58, Method: Composition-based stats. Identities = 67/291 (23%), Positives = 124/291 (42%), Gaps = 61/291 (20%) Query: 62 SMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLK-FCNNVI 120 +L ++P L ++ FA +EY+L + S + ++ F SL LW YL C N Sbjct: 79 QILRKYPLLFGFWKRFATIEYQLFGLKKSIAVLATSVKWF-PTSLELWCDYLNVLCVNNP 137 Query: 121 SHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKI----LEIPL 176 + + +E A++ +G F S FWD ++E +K W+ +++I +E+PL Sbjct: 138 NETDFIRNNFEIAKDLIGKQFLSHPFWDKFIE-----FEVGQKNWHNVQRIYEYIIEVPL 192 Query: 177 HSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKI 236 H +++F+ + + +++ K L + D +L+K + +N Sbjct: 193 HQYARFFTSYKKFLNE----KNLKTTRNIDIVLRKTQTTVN------------------- 229 Query: 237 TKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTH 296 EI+ FESKI ++ + L +D++E W +YL + TD Sbjct: 230 -------------EIWQ-FESKIKQPFFNLGQVL--NDDLENWSRYLKFV----TDPSKS 269 Query: 297 LN-------FQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKF 340 L+ F R L+P +++ W+ Y KWL ++ F Sbjct: 270 LDKEFVMSVFDRCLIPCLYHENTWMMYIKWLTKKNISDEVVVDIYQKANTF 320 >2OND-A nrPDB Length = 308 Score = 159 bits (402), Expect = 3e-39, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 67/150 (44%), Gaps = 19/150 (12%) Query: 269 TLVSSDEIETWIKYLDYT--ITLQTDSLTHLN------FQRALLPLAHYDLVWIKYSKWL 320 T + +++ W KY+ + L+T+ T + +++ LL L H+ +W + +++L Sbjct: 1 TPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYL 60 Query: 321 INSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLN--------EYVLLRNLLEKIE 372 S + LL K + FS + I + S + K N +Y R EK+ Sbjct: 61 EQS-SKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVH 119 Query: 373 SSYSD--NVENVDDFEIFWDYLQFKTFCQN 400 S Y+ +E++D ++ Y++F + Sbjct: 120 SIYNRLLAIEDIDPTLVYIQYMKFARRAEG 149 >5XJC-J nrPDB Length = 848 Score = 66.4 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 52/424 (12%), Positives = 160/424 (37%), Gaps = 38/424 (8%) Query: 19 NVSRYPKSLAYWEKLLNYIVKASAPICK-STEPQLLKLIRCTYSSMLNEFPYLENYYIDF 77 NV+ + W + +A + + R Y + P ++N +I + Sbjct: 325 NVAGARQVFERWMEW-QPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKN-WIKY 382 Query: 78 ALLEYKLGNVSMSHKIFQRGLQAFNQRSLL--LWTSYLKFCNNVISHQKQLFKKYETAEE 135 A E K + + K+++R ++ F + L+ ++ KF +++ Y+ A + Sbjct: 383 ARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKF-EENQKEFERVRVIYKYALD 441 Query: 136 YVGLH-----FFSGEFWDLYL--EQISSRCTSSKKYWNVLRKILEIPLHSFSKF-YALWL 187 + F + ++ + SK+ + ++ P + + F Y + Sbjct: 442 RISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLV 501 Query: 188 QRIDDIMDLKQLSQLTSKDELLKKLK--------IDINYSGRKGPYLQDAKK--KLKKIT 237 + + ++++ + + + K + INY+ + +D ++ ++ + + Sbjct: 502 ESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQAS 561 Query: 238 KEMYMVVQYQVLEIY------SIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQT 291 E+ ++ +++ I + + + ++ + + + Y++ + L+ Sbjct: 562 LELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLRE 621 Query: 292 DSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLL 351 +++ L WIK+++ L D+ A+ + + S + ++ ++L Sbjct: 622 FDRCRKLYEKFLEFGPENCTSWIKFAE-LETILGDIDRARAIYELA--ISQPRLDMPEVL 678 Query: 352 YSVICKLNEYVLLRNLLEKIESSYSDNVENVDDFEIFWDYLQFKTFC--QNSLYSSRYSD 409 + ++ + + E+ + Y ++ +++ + QF+ + SL R Sbjct: 679 WKSYI---DFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFELSSGKEGSLTKCRQIY 735 Query: 410 SQSN 413 ++N Sbjct: 736 EEAN 739 Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 63/364 (17%), Positives = 114/364 (31%), Gaps = 58/364 (15%) Query: 47 STEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSL 106 + + + R + + P + ++ + +E LGNV+ + ++F+R ++ Q Sbjct: 286 EMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEW--QPEE 343 Query: 107 LLWTSYLKF-----------------------CNNVISHQKQ---------LFKKYETAE 134 W SY+ F N I + + K YE A Sbjct: 344 QAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAV 403 Query: 135 EYVGLHFFSGEFWD---LYLEQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRID 191 E+ G + + E Y L +I + K Y ++ ++ Sbjct: 404 EFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFG 463 Query: 192 DIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQVLEI 251 D + +D ++ K + + P+ DA + +V E Sbjct: 464 D--------RRGIEDIIVSKRRFQYEEEVKANPHNYDA------WFDYLRLVESDAEAEA 509 Query: 252 YSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDL 311 + N E I WI Y Y D +A L L + Sbjct: 510 VREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKK 569 Query: 312 V-----WIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNEYVLLRN 366 WI Y+++ I KN L + L K ++ K+ + +L E+ R Sbjct: 570 FTFAKMWILYAQFEIRQKNLSLARRA--LGTSIGKCPKNKLFKVYIELELQLREFDRCRK 627 Query: 367 LLEK 370 L EK Sbjct: 628 LYEK 631 Score = 50.6 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 52/343 (15%), Positives = 114/343 (33%), Gaps = 63/343 (18%) Query: 46 KSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQ-- 103 + E ++ R Y + P+ + + D+ L ++++R + Sbjct: 466 RGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQ 525 Query: 104 ------RSLLLWTSYLKFCNNVISHQKQLFKKYETAEEYV-GLHFFSGEFWDLYLEQISS 156 R + LW +Y + ++ + Y+ + E + F + W LY + Sbjct: 526 EKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILY-----A 580 Query: 157 RCTSSKKYWNVLRKILE--IPLHSFSKFYALWLQ---RIDDIMDLKQLSQLTSKDELLKK 211 + +K ++ R+ L I +K + ++++ ++ + ++L + + + Sbjct: 581 QFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYE-KFLEFGPEN 639 Query: 212 LKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLV 271 I ++ + + +Y E I PE L Sbjct: 640 CTSWIKFAELETILGDI------DRARAIY--------------ELAISQPRLDMPEVL- 678 Query: 272 SSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAK 331 W Y+D+ I + T ++R LL + VWI ++++ Sbjct: 679 -------WKSYIDFEIEQEETERTRNLYRR-LLQRTQHVKVWISFAQF------------ 718 Query: 332 NVLLMGLKFSLKK-TEIIKLLYSVICKLNEYVLLRNLLEKIES 373 L G + SL K +I + + E LLE S Sbjct: 719 -ELSSGKEGSLTKCRQIYEEANKTMRNCEEKEERLMLLESWRS 760 Score = 48.3 bits (113), Expect = 9e-06, Method: Composition-based stats. Identities = 60/397 (15%), Positives = 127/397 (31%), Gaps = 34/397 (8%) Query: 57 RCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFC 116 R T+ + + + + +I +A E L + + I++R L + R++ LW Y + Sbjct: 228 RKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALD-VDYRNITLWLKYAEME 286 Query: 117 NNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPL 176 +Q+ + + +FW Y + R + P Sbjct: 287 MKN----RQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPE 342 Query: 177 HSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSG--RKGPYLQDAKKKLK 234 Y + R ++ + + + + +K I Y+ K Y A+K + Sbjct: 343 EQAWHSYINFELRYKEVDRARTIYER--FVLVHPDVKNWIKYARFEEKHAYFAHARKVYE 400 Query: 235 -------KITKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTI 287 + ++ V + E ++ + Y + + + D E + Y + Sbjct: 401 RAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEK 460 Query: 288 TLQTD--------SLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLK 339 S ++ + H W Y + L+ S + + V + Sbjct: 461 KFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLR-LVESDAEAEAVREVYERAIA 519 Query: 340 FSLKKTEIIKLLYSVICKLNE--YVLLRNL-LEKIESSYSDNVENVDD-----FEIFWDY 391 E + +N Y L E+ Y ++E + +++ Y Sbjct: 520 NVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILY 579 Query: 392 LQFKTFCQNSLYSSRYSDSQSNGLLNKELFDKVWKRL 428 QF+ Q +L +R + S G K KV+ L Sbjct: 580 AQFEIR-QKNLSLARRALGTSIGKCPKNKLFKVYIEL 615 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 37/95 (38%), Gaps = 1/95 (1%) Query: 245 QYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALL 304 Q ++ + + + K+ + I WIKY + +L+ ++RAL Sbjct: 211 QQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALD 270 Query: 305 PLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLK 339 +W+KY++ + + A+N+ + Sbjct: 271 VDYRNITLWLKYAE-MEMKNRQVNHARNIWDRAIT 304 >5CTQ-A nrPDB Length = 561 Score = 63.7 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 69/427 (16%), Positives = 157/427 (36%), Gaps = 70/427 (16%) Query: 13 FSTLTLNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLEN 72 F L + R + L+ N V + E +++ R S + FP E Sbjct: 41 FQGNQLEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEI---FPLTEE 97 Query: 73 YYIDFALLEYKL--GNVSMSH--KIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQ---KQ 125 ++++ E + + H +F++ ++ + ++ W Y ++ I + ++ Sbjct: 98 LWLEWLHDEISMAQDGLDREHVYDLFEKAVKDYICPNI--WLEYGQYSVGGIGQKGGLEK 155 Query: 126 LFKKYETAEEYVGLHFFSG-EFWDLYLEQISSRCTSSK--KYWNVLRKILEIPLHSFSKF 182 + +E A VGLH G W+ Y E S+ +++ K ++ R+ L IPL+ Sbjct: 156 VRSVFERALSSVGLHMTKGLALWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEAT 215 Query: 183 YALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYM 242 +A + + +D + + NY+ Sbjct: 216 FAEYEEWSEDPIP----------------ESVIQNYNK---------------------- 237 Query: 243 VVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRA 302 Q LE Y +E + + + + Y+D+ + + + L F+RA Sbjct: 238 --ALQQLEKYKPYEEALLQ---------AEAPRLAEYQAYIDFEMKIGDPARIQLIFERA 286 Query: 303 LLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLN-EY 361 L+ +WI+YS++L +V ++ + + + ++ Sbjct: 287 LVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDH 346 Query: 362 VLLRNLLEK-IESSYSDNVENVDDFEIFWDYLQ----FKTFCQNSLYSSRYSDSQSNGLL 416 ++ EK + + + + V+ ++ + DYL+ FK L R + +++ L Sbjct: 347 QVISVTFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYL 406 Query: 417 NKELFDK 423 +E+ ++ Sbjct: 407 KQEVEER 413 Score = 32.1 bits (71), Expect = 0.67, Method: Composition-based stats. Identities = 35/261 (13%), Positives = 85/261 (32%), Gaps = 19/261 (7%) Query: 74 YIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKYETA 133 Y + E K+G+ + IF+R L N LW Y ++ + + + + + A Sbjct: 263 YQAYIDFEMKIGDPARIQLIFERALVE-NCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRA 321 Query: 134 EEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDDI 193 ++ W YL + + K L + + +W +D + Sbjct: 322 IRNCP---WTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIWQAYLDYL 378 Query: 194 MDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQVLEIYS 253 Q +SK+ + L+ K+++++ E +++ ++ Sbjct: 379 RRRVDFKQDSSKELEELRAAFTR--------ALEYLKQEVEERFNESG-DPSCVIMQNWA 429 Query: 254 IFESKI------YINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLA 307 E+++ + S T ++ W++Y + RA+ + Sbjct: 430 RIEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTS 489 Query: 308 HYDLVWIKYSKWLINSKNDLL 328 Y + + ++ L Sbjct: 490 DYPEHVCEVLLTMERTEGSLE 510 >5JPZ-A nrPDB Length = 509 Score = 63.3 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 68/422 (16%), Positives = 156/422 (36%), Gaps = 70/422 (16%) Query: 18 LNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDF 77 L + R + L+ N V + E +++ R S + FP E ++++ Sbjct: 31 LEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEI---FPLTEELWLEW 87 Query: 78 ALLEYKL--GNVSMSH--KIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQ---KQLFKKY 130 E + + H +F++ ++ + ++ W Y ++ I + +++ + Sbjct: 88 LHDEISMAQDGLDREHVYDLFEKAVKDYICPNI--WLEYGQYSVGGIGQKGGLEKVRSVF 145 Query: 131 ETAEEYVGLHFFSG-EFWDLYLEQISSRCTSSK--KYWNVLRKILEIPLHSFSKFYALWL 187 E A VGLH G W+ Y E S+ +++ K ++ R+ L IPL+ +A + Sbjct: 146 ERALSSVGLHMTKGLALWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYE 205 Query: 188 QRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQ 247 + +D + + NY+ Q Sbjct: 206 EWSEDPIP----------------ESVIQNYNK------------------------ALQ 225 Query: 248 VLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLA 307 LE Y +E + + + + Y+D+ + + + L F+RAL+ Sbjct: 226 QLEKYKPYEEALLQ---------AEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENC 276 Query: 308 HYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLN-EYVLLRN 366 +WI+YS++L +V ++ + + + ++ ++ Sbjct: 277 LVPDLWIRYSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISV 336 Query: 367 LLEK-IESSYSDNVENVDDFEIFWDYLQ----FKTFCQNSLYSSRYSDSQSNGLLNKELF 421 EK + + + + V+ ++ + DYL+ FK L R + +++ L +E+ Sbjct: 337 TFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYLKQEVE 396 Query: 422 DK 423 ++ Sbjct: 397 ER 398 Score = 32.1 bits (71), Expect = 0.71, Method: Composition-based stats. Identities = 35/261 (13%), Positives = 85/261 (32%), Gaps = 19/261 (7%) Query: 74 YIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKYETA 133 Y + E K+G+ + IF+R L N LW Y ++ + + + + + A Sbjct: 248 YQAYIDFEMKIGDPARIQLIFERALVE-NCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRA 306 Query: 134 EEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDDI 193 ++ W YL + + K L + + +W +D + Sbjct: 307 IRNCP---WTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIWQAYLDYL 363 Query: 194 MDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQVLEIYS 253 Q +SK+ + L+ K+++++ E +++ ++ Sbjct: 364 RRRVDFKQDSSKELEELRAAFTR--------ALEYLKQEVEERFNESG-DPSCVIMQNWA 414 Query: 254 IFESKI------YINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLA 307 E+++ + S T ++ W++Y + RA+ + Sbjct: 415 RIEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTS 474 Query: 308 HYDLVWIKYSKWLINSKNDLL 328 Y + + ++ L Sbjct: 475 DYPEHVCEVLLTMERTEGSLE 495 >5JJX-A nrPDB Length = 314 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 55/315 (17%), Positives = 116/315 (36%), Gaps = 64/315 (20%) Query: 18 LNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDF 77 L + R + L+ N V + E +++ R S + FP E ++++ Sbjct: 17 LEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEI---FPLTEELWLEW 73 Query: 78 ALLEYKL--GNVSMSH--KIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQ---KQLFKKY 130 E + + H +F++ ++ + ++ W Y ++ I + +++ + Sbjct: 74 LHDEISMAQDGLDREHVYDLFEKAVKDYICPNI--WLEYGQYSVGGIGQKGGLEKVRSVF 131 Query: 131 ETAEEYVGLHFFSG-EFWDLYLEQISSRCTSSK--KYWNVLRKILEIPLHSFSKFYALWL 187 E A VGLH G W+ Y E S+ +++ K ++ R+ L IPL+ +A + Sbjct: 132 ERALSSVGLHMTKGLALWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYE 191 Query: 188 QRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQ 247 + +D + + NY+ Q Sbjct: 192 EWSEDPIP----------------ESVIQNYNK------------------------ALQ 211 Query: 248 VLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLA 307 LE Y +E + + + + Y+D+ + + + L F+RAL+ Sbjct: 212 QLEKYKPYEEALLQ---------AEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENC 262 Query: 308 HYDLVWIKYSKWLIN 322 +WI+YS++L Sbjct: 263 LVPDLWIRYSQYLDR 277 >4EBA-A nrPDB Length = 645 Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 48/348 (13%), Positives = 117/348 (33%), Gaps = 70/348 (20%) Query: 5 TALIHDENFSTLTLN--VSRYPKSLAYWEKLLNY--IVKASAPICKSTEPQLLKLIRCTY 60 T+ + DE+ LN + P + + KLL + +K K + T+ Sbjct: 8 TSRVRDESDVIGKLNDMIEEQPTDIFLYVKLLKHHVSLKQW------------KQVYETF 55 Query: 61 SSMLNEFPYLENYYIDFALLEY-KLGNVSMS--HKIFQRGL-QAFNQRSLLLWTSYLKFC 116 + + FP + N + LE+ K+ + + + R L + L LW SY+ + Sbjct: 56 DKLHDRFPLMANIWCMRLSLEFDKMEELDAAVIEPVLARCLSKELGNNDLSLWLSYITYV 115 Query: 117 ---NNVISHQKQLFK----KYETAEEYVGL-HFFSGEFWDLYLEQISSRCTSSKKYWNVL 168 N++I+ ++ ++ + + S +FW+ YL + ++W + Sbjct: 116 RKKNDIITGGEEARNIVIQAFQVVVDKCAIFEPKSIQFWNEYLHFL--------EHWKPV 167 Query: 169 RKILEIPLHSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQD 228 K E QR+ I ++L + + + Y+ + Q Sbjct: 168 NKFEE-------------QQRVQYI---RKLYKTLLCQPMDCLESMWQRYTQWEQDVNQL 211 Query: 229 AKKKLKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSS----------DEIET 278 ++ YM + + + + + N + S ++ Sbjct: 212 TARRHIGELSAQYMNAR-SLYQDWLNITKGLKRNLPITLNQATESNLPKPNEYDVQQLLI 270 Query: 279 WIKYLDYTITLQTD-------SLTHLNFQRALLPLAHYDLVWIKYSKW 319 W++++ + + + + + +A + +W + + Sbjct: 271 WLEWIRWESDNKLELSDDLHKARMTYVYMQAAQHVCFAPEIWFNMANY 318 >5LJ5-S nrPDB Length = 687 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 56/336 (16%), Positives = 126/336 (37%), Gaps = 22/336 (6%) Query: 44 ICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQ 103 + ++++R Y+ + P + N + F E + N + +I+ + + A Sbjct: 140 LIVEESLNNVEIVRSLYTKWCSLEPGV-NAWNSFVDFEIRQKNWNGVREIYSKYVMA--H 196 Query: 104 RSLLLWTSYLKFCNNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKK 163 + W +++F N + + Y A + V + + + W ++ +S Sbjct: 197 PQMQTWLKWVRFENRHGN-TEFTRSVYSLAIDTVA-NLQNLQIWSD---MEVAKLVNSFA 251 Query: 164 YWNVLRKILEIPLHSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKG 223 +W ++ E + W + + L + + ++ I+Y + Sbjct: 252 HWEAAQQEYERSSALYQIAIEKWP---SNQLLKAGLLDFEKQFGDINSIEETISYKRKME 308 Query: 224 PYLQDAKKKLKKITKEMYM--VVQYQVLEIYSIFESKIYINYYT-SPETLVSSDEIETWI 280 + T +Y+ + + +I FE I + + + I W+ Sbjct: 309 YETILSNNAYDYDTWWLYLDLISESFPKQIMQTFEKAIVDSRPKELSKNVQWKRYIYLWM 368 Query: 281 KYLDYTITLQTDSLTHLN-FQRAL---LPLAHY--DLVWIKYSKWLINSKNDLLGAKNVL 334 +Y+ Y +SL FQR + +P H+ +W+ Y+K+LI +D+ A+ +L Sbjct: 369 RYICYVELELENSLLEEELFQRLIDDIIPHKHFTFSKIWLMYAKFLIR-HDDVPKARKIL 427 Query: 335 LMGLKFSLKKTEIIKLLYSVICKLNEYVLLRNLLEK 370 + K + K + KL E+ +R + EK Sbjct: 428 GKAIGLC-PKAKTFKGYIELEVKLKEFDRVRKIYEK 462 Score = 34.8 bits (78), Expect = 0.10, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 40/96 (41%), Gaps = 1/96 (1%) Query: 275 EIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVL 334 ++ WI+Y + I F+RALL + + +WI+Y + A+N++ Sbjct: 64 DMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLWIRYID-AELKVKCINHARNLM 122 Query: 335 LMGLKFSLKKTEIIKLLYSVICKLNEYVLLRNLLEK 370 + + ++ V LN ++R+L K Sbjct: 123 NRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTK 158 Score = 32.9 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 22/153 (14%), Positives = 53/153 (34%), Gaps = 23/153 (15%) Query: 20 VSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFAL 79 + R + W + + E ++ R + L +I + Sbjct: 58 LKRNRLDMGQWIRYAQF----------EIEQHDMRRARSIFERALLVDSSFIPLWIRYID 107 Query: 80 LEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKY-ETAEEYVG 138 E K+ ++ + + R + + R LW YL +++ + + Y + G Sbjct: 108 AELKVKCINHARNLMNRAI-STLPRVDKLWYKYL-IVEESLNNVEIVRSLYTKWCSLEPG 165 Query: 139 LHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKI 171 ++ W+ +++ +K WN +R+I Sbjct: 166 VN-----AWNSFVD-----FEIRQKNWNGVREI 188 Score = 32.5 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 36/287 (12%), Positives = 91/287 (31%), Gaps = 38/287 (13%) Query: 45 CKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQR 104 S E + + Y ++L+ Y + + + L + + F++ + + Sbjct: 294 INSIEETISYKRKMEYETILSNNAYDYDTWWLYLDLISESFP-KQIMQTFEKAIVDSRPK 352 Query: 105 SLL----------LWTSYLKFCNNVISHQKQLFKKYETAEEYV--GLHFFSGEFWDLYLE 152 L LW Y+ + + + + ++ + + HF + W +Y + Sbjct: 353 ELSKNVQWKRYIYLWMRYICYVELELENSLLEEELFQRLIDDIIPHKHFTFSKIWLMYAK 412 Query: 153 QISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKKL 212 + K + + I P K Y ++ + ++++ + + L Sbjct: 413 FLIRHDDVPKARKILGKAIGLCPKAKTFKGYIELEVKLKEFDRVRKIYE-KFIEFQPSDL 471 Query: 213 KIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVS 272 +I Y + + +Y + L+ S F +K Sbjct: 472 QIWSQYGELEENLGD------WDRVRGIYTIA----LDENSDFLTK-------------- 507 Query: 273 SDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKW 319 +I KY+ + Q ++R L + WI+++ + Sbjct: 508 EAKIVLLQKYITFETESQEFEKARKLYRRYLELNQYSPQSWIEFAMY 554 >6AHD-N nrPDB Length = 941 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 54/355 (15%), Positives = 114/355 (32%), Gaps = 43/355 (12%) Query: 39 KASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGL 98 K+ ++ Q + + + P YI A LE ++ ++ ++ L Sbjct: 341 KSEDVWLEAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELET---DIRAKKRVLRKAL 397 Query: 99 QAFNQRSLLLWTSYLKFCNNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRC 158 + S+ LW + ++ + A E S E W +R Sbjct: 398 EHV-PNSVRLWKAAVEL-----EEPEDARIMLSRAVECCPT---SVELW-----LALARL 443 Query: 159 TSSKKYWNVLRKILE-IPLHSFSKFYALWLQRID------DIMDLKQLSQLTSKDELLKK 211 + + VL K E IP A L+ + + + + ++ L + + + Sbjct: 444 ETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINR 503 Query: 212 LKIDINYSGRKGPYLQDAKK----------KLKKITKEMYMVVQYQVLEIYSIFESKIYI 261 + I + A +++ ++ + ++ E I Sbjct: 504 EQ-WIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAI 562 Query: 262 NYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYS--KW 319 Y W++ + T QRA+ +++W+ + KW Sbjct: 563 YAYALQVFPSKKS---VWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKW 619 Query: 320 LINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNEYVLLRNLLEKIESS 374 L D+ A+++L + + + EI + + +EY R LL K SS Sbjct: 620 L---AGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSS 671 Score = 35.6 bits (80), Expect = 0.061, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 47 STEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSL 106 + ++++ R Y+ L + P+ ++ + LE K+G ++ + I ++ N ++ Sbjct: 719 EEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLK-NPKNP 777 Query: 107 LLWTSYLKF 115 LW ++ Sbjct: 778 GLWLESVRL 786 Score = 33.6 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 39/275 (14%), Positives = 86/275 (31%), Gaps = 39/275 (14%) Query: 53 LKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSY 112 ++ + L + ++ +E + + + + + +GL+ S LW Sbjct: 691 IRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKK-CPHSTPLWL-- 747 Query: 113 LKFCNNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKIL 172 + + QL + E+ + + W LE + + K N+ ++ Sbjct: 748 --LLSRLEEKIGQLTRARAILEKSRLKNPKNPGLW---LESVRLEYRAGLK--NIANTLM 800 Query: 173 EIPLHSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKK 232 L LW + I ++ + + S D L K P++ A K Sbjct: 801 AKALQECPNSGILWSEAI--FLEARPQRRTKSVDALKK---------CEHDPHVLLAVAK 849 Query: 233 LKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTD 292 L Q ++ + F + I SD + W + + + T+ Sbjct: 850 L--------FWSQRKITKAREWFHRTVKI----------DSDLGDAWAFFYKFELQHGTE 891 Query: 293 SLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDL 327 +R + +W SK + N + + Sbjct: 892 EQQEEVRKRCESAEPRHGELWCAVSKDIANWQKKI 926 >2UY1-A nrPDB Length = 493 Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 46/111 (41%), Gaps = 5/111 (4%) Query: 82 YKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKYETAEEYVGLHF 141 Y + +F R L+ +L LW Y+++ V + +L++ YE ++ Sbjct: 25 YMSKDYRSLESLFGRCLKK--SYNLDLWMLYIEYVRKVSQKKFKLYEVYEFTLGQFENYW 82 Query: 142 FSGEFWDLYLEQ---ISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQR 189 S + Y+E+ I T +K N + L+ P+ S S+ + + Sbjct: 83 DSYGLYKEYIEEEGKIEDEQTRIEKIRNGYMRALQTPMGSLSELWKDFENF 133 >5WLC-LP nrPDB Length = 440 Score = 42.1 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 9/102 (8%) Query: 21 SRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALL 80 +++P+ L +W LNY + K I Y+ +L P + +I A Sbjct: 101 NKFPQDLKFWAMYLNY-------MKARGNQTSYKKIHNIYNQLLKLHPTNVDIWISCAKY 153 Query: 81 EYK-LGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVIS 121 EY+ N IFQ GL+ FN LW Y+KF N I+ Sbjct: 154 EYEVHANFKSCRNIFQNGLR-FNPDVPKLWYEYVKFELNFIT 194 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 37/98 (37%), Gaps = 11/98 (11%) Query: 60 YSSMLNEFPYLENYYIDFALLEYKLGN---VSMSHKIFQRGLQAFNQRSLLLWTSYLKFC 116 Y N+FP ++ + GN H I+ + L + ++ +W S K+ Sbjct: 96 YQRGTNKFPQDLKFWAMYLNYMKARGNQTSYKKIHNIYNQ-LLKLHPTNVDIWISCAKYE 154 Query: 117 NNVISHQKQLFKKYETAEEYVGLHFFSG--EFWDLYLE 152 V ++ K ++ GL F + W Y++ Sbjct: 155 YEVHANFKSCRNIFQN-----GLRFNPDVPKLWYEYVK 187 Score = 28.6 bits (62), Expect = 6.4, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 28/71 (39%), Gaps = 3/71 (4%) Query: 274 DEIETWIKYLDYTITLQTDSL---THLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGA 330 +++ W YL+Y + H + + L +WI +K+ + Sbjct: 105 QDLKFWAMYLNYMKARGNQTSYKKIHNIYNQLLKLHPTNVDIWISCAKYEYEVHANFKSC 164 Query: 331 KNVLLMGLKFS 341 +N+ GL+F+ Sbjct: 165 RNIFQNGLRFN 175 >5JJW-A nrPDB Length = 300 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 73/187 (39%), Gaps = 15/187 (8%) Query: 243 VVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRA 302 Q LE Y +E + + + + Y+D+ + + + L F+RA Sbjct: 8 NKALQQLEKYKPYEEALLQ---------AEAPRLAEYQAYIDFEMKIGDPARIQLIFERA 58 Query: 303 LLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLN-EY 361 L+ +WI+YS++L +V ++ + + + ++ Sbjct: 59 LVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDH 118 Query: 362 VLLRNLLEK-IESSYSDNVENVDDFEIFWDYLQ----FKTFCQNSLYSSRYSDSQSNGLL 416 ++ EK + + + + V+ ++ + DYL+ FK L R + +++ L Sbjct: 119 QVISVTFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYL 178 Query: 417 NKELFDK 423 +E+ ++ Sbjct: 179 KQEVEER 185 Score = 32.5 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 47/124 (37%), Gaps = 6/124 (4%) Query: 54 KLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKI-FQRGLQA-FNQRS--LLLW 109 L+ ++ + P+ + + L + G + F++ L A F Q + + +W Sbjct: 84 DLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIW 143 Query: 110 TSYLKFCNNVISHQKQLFKKYET--AEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNV 167 +YL + + ++ K+ E A L + E + + E C + + + Sbjct: 144 QAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYLKQEVEERFNESGDPSCVIMQNWARI 203 Query: 168 LRKI 171 ++ Sbjct: 204 EARL 207 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 35/261 (13%), Positives = 85/261 (32%), Gaps = 19/261 (7%) Query: 74 YIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKYETA 133 Y + E K+G+ + IF+R L N LW Y ++ + + + + + A Sbjct: 35 YQAYIDFEMKIGDPARIQLIFERALVE-NCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRA 93 Query: 134 EEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDDI 193 ++ W YL + + K L + + +W +D + Sbjct: 94 IRNCP---WTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIWQAYLDYL 150 Query: 194 MDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQVLEIYS 253 Q +SK+ + L+ K+++++ E +++ ++ Sbjct: 151 RRRVDFKQDSSKELEELRAAFTR--------ALEYLKQEVEERFNESG-DPSCVIMQNWA 201 Query: 254 IFESKI------YINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLA 307 E+++ + S T ++ W++Y + RA+ + Sbjct: 202 RIEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTS 261 Query: 308 HYDLVWIKYSKWLINSKNDLL 328 Y + + ++ L Sbjct: 262 DYPEHVCEVLLTMERTEGSLE 282 >5CTR-A nrPDB Length = 338 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 73/187 (39%), Gaps = 15/187 (8%) Query: 243 VVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRA 302 Q LE Y +E + + + + Y+D+ + + + L F+RA Sbjct: 13 NKALQQLEKYKPYEEALLQ---------AEAPRLAEYQAYIDFEMKIGDPARIQLIFERA 63 Query: 303 LLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLN-EY 361 L+ +WI+YS++L +V ++ + + + ++ Sbjct: 64 LVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDH 123 Query: 362 VLLRNLLEK-IESSYSDNVENVDDFEIFWDYLQ----FKTFCQNSLYSSRYSDSQSNGLL 416 ++ EK + + + + V+ ++ + DYL+ FK L R + +++ L Sbjct: 124 QVISVTFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYL 183 Query: 417 NKELFDK 423 +E+ ++ Sbjct: 184 KQEVEER 190 Score = 32.5 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 47/124 (37%), Gaps = 6/124 (4%) Query: 54 KLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKI-FQRGLQA-FNQRS--LLLW 109 L+ ++ + P+ + + L + G + F++ L A F Q + + +W Sbjct: 89 DLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIW 148 Query: 110 TSYLKFCNNVISHQKQLFKKYET--AEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNV 167 +YL + + ++ K+ E A L + E + + E C + + + Sbjct: 149 QAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYLKQEVEERFNESGDPSCVIMQNWARI 208 Query: 168 LRKI 171 ++ Sbjct: 209 EARL 212 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 35/261 (13%), Positives = 85/261 (32%), Gaps = 19/261 (7%) Query: 74 YIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKYETA 133 Y + E K+G+ + IF+R L N LW Y ++ + + + + + A Sbjct: 40 YQAYIDFEMKIGDPARIQLIFERALVE-NCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRA 98 Query: 134 EEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDDI 193 ++ W YL + + K L + + +W +D + Sbjct: 99 IRNCP---WTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIWQAYLDYL 155 Query: 194 MDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQVLEIYS 253 Q +SK+ + L+ K+++++ E +++ ++ Sbjct: 156 RRRVDFKQDSSKELEELRAAFTR--------ALEYLKQEVEERFNESG-DPSCVIMQNWA 206 Query: 254 IFESKI------YINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLA 307 E+++ + S T ++ W++Y + RA+ + Sbjct: 207 RIEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTS 266 Query: 308 HYDLVWIKYSKWLINSKNDLL 328 Y + + ++ L Sbjct: 267 DYPEHVCEVLLTMERTEGSLE 287 >3JB9-R nrPDB Length = 674 Score = 37.5 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 36/85 (42%), Gaps = 3/85 (3%) Query: 47 STEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSL 106 + + + R + + + P ++ + + +E LGN++ ++F+R L+ + Sbjct: 114 EMKNRNINHARNLFDRAVTQLPRVDKLWYKYVYMEEMLGNITGCRQVFERWLKW--EPDE 171 Query: 107 LLWTSYLKFCNNVISHQKQLFKKYE 131 W SY++ ++ YE Sbjct: 172 NCWMSYIRM-ERRYHENERARGIYE 195 Score = 36.7 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 40/100 (40%), Gaps = 2/100 (2%) Query: 271 VSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGA 330 V S I W+KY++ + + + F RA+ L D +W KY ++ ++ G Sbjct: 99 VDSTYIPLWLKYIECEMKNRNINHARNLFDRAVTQLPRVDKLWYKYV-YMEEMLGNITGC 157 Query: 331 KNVLLMGLKFSLKKTEIIKLLYSVICKLNEYVLLRNLLEK 370 + V LK+ + + +E R + E+ Sbjct: 158 RQVFERWLKWE-PDENCWMSYIRMERRYHENERARGIYER 196 Score = 32.9 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 14/97 (14%), Positives = 34/97 (35%), Gaps = 9/97 (9%) Query: 57 RCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYL--K 114 R + + +++ + E + + +F+R L + + LW Y+ + Sbjct: 56 RKEFEDAIRRNRLAMGHWMRYGQWELDQKEFARARSVFERALD-VDSTYIPLWLKYIECE 114 Query: 115 FCNNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYL 151 N I+H ++ A + + W Y+ Sbjct: 115 MKNRNINHA---RNLFDRAVTQLP---RVDKLWYKYV 145 Score = 29.8 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 11/85 (12%) Query: 255 FESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWI 314 FE I N W++Y + + + + F+RAL + Y +W+ Sbjct: 59 FEDAIRRNRLAMGH----------WMRYGQWELDQKEFARARSVFERALDVDSTYIPLWL 108 Query: 315 KYSKWLINSKNDLLGAKNVLLMGLK 339 KY + ++ A+N+ + Sbjct: 109 KYIE-CEMKNRNINHARNLFDRAVT 132 >3JCM-G nrPDB Length = 899 Score = 35.9 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 51/128 (39%), Gaps = 13/128 (10%) Query: 55 LIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLK 114 R L + P +YI +E +LGN+ + + + LQ F + LLW +K Sbjct: 721 RARSILDRGLLKNPDDVLFYIAKIQMEIRLGNLDQAELLVTQALQKF-PSNALLWVEQIK 779 Query: 115 FC--NNVISHQKQLF-------KKYETAEEYVGLHFFSGEFWD---LYLEQISSRCTSSK 162 N S +K +F + +G+ F++ ++ +LE+ +C+ Sbjct: 780 LFKHGNKSSLKKTIFQDALRRTQNDHRVLLEIGVSFYAEAQYETSLKWLERALKKCSRYG 839 Query: 163 KYWNVLRK 170 W L + Sbjct: 840 DTWVWLFR 847 >5GMK-d nrPDB Length = 687 Score = 35.6 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 40/96 (41%), Gaps = 1/96 (1%) Query: 275 EIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVL 334 ++ WI+Y + I F+RALL + + +WI+Y + A+N++ Sbjct: 64 DMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLWIRYID-AELKVKCINHARNLM 122 Query: 335 LMGLKFSLKKTEIIKLLYSVICKLNEYVLLRNLLEK 370 + + ++ V LN ++R+L K Sbjct: 123 NRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTK 158 Score = 34.4 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 22/153 (14%), Positives = 53/153 (34%), Gaps = 23/153 (15%) Query: 20 VSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFAL 79 + R + W + + E ++ R + L +I + Sbjct: 58 LKRNRLDMGQWIRYAQF----------EIEQHDMRRARSIFERALLVDSSFIPLWIRYID 107 Query: 80 LEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKY-ETAEEYVG 138 E K+ ++ + + R + + R LW YL +++ + + Y + G Sbjct: 108 AELKVKCINHARNLMNRAI-STLPRVDKLWYKYL-IVEESLNNVEIVRSLYTKWCSLEPG 165 Query: 139 LHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKI 171 ++ W+ +++ +K WN +R+I Sbjct: 166 VN-----AWNSFVD-----FEIRQKNWNGVREI 188 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 34/97 (35%), Gaps = 9/97 (9%) Query: 57 RCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLK-- 114 R Y L +I +A E + ++ + IF+R L + + LW Y+ Sbjct: 51 RTEYEGYLKRNRLDMGQWIRYAQFEIEQHDMRRARSIFERALL-VDSSFIPLWIRYIDAE 109 Query: 115 FCNNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYL 151 I+H + L + + + W YL Sbjct: 110 LKVKCINHARNLMNR------AISTLPRVDKLWYKYL 140 >6ICZ-I nrPDB Length = 855 Score = 34.0 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 18/145 (12%), Positives = 39/145 (26%), Gaps = 12/145 (8%) Query: 35 NYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFAL---LEYKLG-----N 86 + VK + + + Y L P + + + K Sbjct: 32 QFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPA 91 Query: 87 VSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKYETAEEY--VGLHFFSG 144 + +R F + LW Y +F + + ++ A + H Sbjct: 92 YEDVNNCHERAFV-FMHKMPRLWLDYCQFLMDQGRVT-HTRRTFDRALRALPITQHSRIW 149 Query: 145 EFWDLYLEQISSRCTSSKKYWNVLR 169 + +L T+ + Y L+ Sbjct: 150 PLYLRFLRSHPLPETAVRGYRRFLK 174 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 28/72 (38%), Gaps = 3/72 (4%) Query: 279 WIKYLDYTITLQTDSLTHLNFQRAL--LPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLM 336 W+ Y + + + T F RAL LP+ + +W Y ++L + + Sbjct: 113 WLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRG-YRR 171 Query: 337 GLKFSLKKTEII 348 LK S + E Sbjct: 172 FLKLSPESAEEY 183 Score = 30.2 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 37/124 (29%), Gaps = 3/124 (2%) Query: 276 IETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLL 335 ++ W D +L T T + R L + I Y+ +L K K Sbjct: 484 LKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFK-AYE 542 Query: 336 MGLKFSLKKTEIIKLLYSVICKLNEYVLLRNLLEKIESSYSDNVENVDDFEIFWDYLQFK 395 G SL K + ++S LE+ + ++ YL + Sbjct: 543 RG--ISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYA 600 Query: 396 TFCQ 399 + Sbjct: 601 QLEE 604 >5MQ0-T nrPDB Length = 877 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 21/135 (15%), Positives = 50/135 (37%), Gaps = 13/135 (9%) Query: 20 VSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFAL 79 + + P+++ W++ + Y E + K IR Y ++F + + D+ Sbjct: 30 IQKTPQNILTWKRYIEY---------WKEEGRTDKQIRWLYERFCSQFVTDTSIWEDYIR 80 Query: 80 LE--YKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKYETAEEYV 137 E ++ S +FQR L++ + + SYL+ + ++ + Sbjct: 81 WESTKEVVETSRIFWLFQRCLKSCVRDCDRICLSYLELAIEQYDLA-MIRHALASSLMKM 139 Query: 138 GLHFFSGEFWDLYLE 152 + WD ++ Sbjct: 140 ERE-MHRKVWDPVIK 153 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 21/53 (39%), Gaps = 1/53 (1%) Query: 268 ETLVSSDEIETWIKYLD-YTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKW 319 E + I TW +Y++ + +TD ++R +W Y +W Sbjct: 29 EIQKTPQNILTWKRYIEYWKEEGRTDKQIRWLYERFCSQFVTDTSIWEDYIRW 81 Score = 28.2 bits (61), Expect = 9.6, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 29/70 (41%), Gaps = 7/70 (10%) Query: 103 QRSLLLWTSYLKFCNNVISHQKQLFKKYETAEEYVGLHFFSG-EFWDLYLEQISSRC--T 159 +++L W Y+++ KQ+ YE F + W+ Y+ S++ Sbjct: 34 PQNILTWKRYIEYWKEEGRTDKQIRWLYE----RFCSQFVTDTSIWEDYIRWESTKEVVE 89 Query: 160 SSKKYWNVLR 169 +S+ +W R Sbjct: 90 TSRIFWLFQR 99 >3STO-A nrPDB Length = 406 Score = 30.6 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 10/93 (10%) Query: 332 NVLLMGLKFSLKKTEIIKLLYSVICKLNEYVLLRNLLEKIESSYSDNVENVDDFEIFWDY 391 N L F +K E + + + I Y + R E I + ++ VD Sbjct: 98 NSLTSEKTFLNEKEENVVRISTGIFVEKTYEVERRFNESIANDSEGELKQVD-------- 149 Query: 392 LQFKTFCQNSLYSSRYSDSQSNGLLNKELFDKV 424 F ++ + + D QSNGLL K D + Sbjct: 150 --FSNRTSATVDINDWVDQQSNGLLEKFFTDDI 180 >4AEZ-C nrPDB Length = 223 Score = 30.2 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 22/142 (15%), Positives = 38/142 (26%), Gaps = 32/142 (22%) Query: 274 DEIETWIKYLDYTITLQTDSLT-----HLNFQRALLPLAHYDL---------VWIKYSKW 319 D ++ WI Y+ +T+ T +R L +W++Y + Sbjct: 70 DPLQVWIDYIKWTLDNFPQGETKTSGLVTLLERCTREFVRNPLYKDDVRYLRIWMQYVNY 129 Query: 320 LINSKN--DLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNEYVLLRNLLEKIESSYSD 377 + L ++ F + Y R L +K + Y Sbjct: 130 IDEPVELFSFLAHHHIGQESSIFYEEYAN--------------YFESRGLFQKADEVYQK 175 Query: 378 NVE-NVDDFEIFWD-YLQFKTF 397 F F Y QF Sbjct: 176 GKRMKAKPFLRFQQKYQQFTHR 197 >4PFU-A nrPDB Length = 547 Score = 29.4 bits (64), Expect = 4.7, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 21/43 (48%) Query: 118 NVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTS 160 NV + + +E A++Y G+H+ S W ++E +R Sbjct: 81 NVPLTSEDVRFTFEIAKKYKGIHYSSVWEWLDHIETPDNRTVI 123 >3NYZ-A nrPDB Length = 261 Score = 29.0 bits (63), Expect = 5.3, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 44/109 (40%), Gaps = 10/109 (9%) Query: 283 LDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAK-NVLLMGLKFS 341 L+Y + + +N + L D+ ++++ + DL + N S Sbjct: 146 LEYARSYGMEPAIVINDENDL------DIALRIGARFIEIASRDLETLEINKENQRKLIS 199 Query: 342 LKKTEIIKLLYSVICKLNEYVLLRNLLEK---IESSYSDNVENVDDFEI 387 + + ++K+ + I + NE LR L I SS N E + +F + Sbjct: 200 MIPSNVVKVAWQGISERNEIEELRKLGVNAFGIGSSLMRNPEKIKEFIL 248 >4K8X-A nrPDB Length = 775 Score = 29.0 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 36/100 (36%), Gaps = 11/100 (11%) Query: 35 NYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLE-------YKLGNV 87 +YI + P+ + + + + Y PY D + +E + G V Sbjct: 6 DYITENGKPVIRVFKKEN-GEFKIEYDRTFE--PYFYALLKDDSAIEDVKKVTAKRHGTV 62 Query: 88 SMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLF 127 + ++ + F R + +W Y +V + + ++ Sbjct: 63 VKVKRA-EKVQKKFLGRPIEVWKLYFNHPQDVPAIRDRIR 101 >4JB7-A nrPDB Length = 256 Score = 28.6 bits (62), Expect = 7.1, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Query: 243 VVQYQVLEIYSIFESKIYINYYTSP---ETLVSSDEIETWIKYLDYTITLQT 291 V + + +E F S I++ S + V ++I+ WI ++D+ I T Sbjct: 152 VGRMKNVEKLQAFRSNIHVFAPNSGSARKAFVDGEDIDAWITWVDWAIANPT 203 >2CFA-B nrPDB Length = 217 Score = 28.6 bits (62), Expect = 7.8, Method: Composition-based stats. Identities = 23/180 (12%), Positives = 62/180 (34%), Gaps = 14/180 (7%) Query: 113 LKFCNNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKIL 172 + + V + + Q+ K + + + W ++ + + R I Sbjct: 23 IAYAARVSNPENQINNKTASGLLK---YCIRHKHWSIFETAFMTLELKTS------RGIA 73 Query: 173 EIPLHSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKK 232 + S + + QR +M+ Q +D ++ +D + + + +K Sbjct: 74 AQVIRHRSFHFQEFSQRYASVMETPPPHQARFQDHKNRQNSLDTVPEDDQTWWATEQEKL 133 Query: 233 LKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTD 292 + + ++ + + + F + ++P T+ S I WI Y++ + T Sbjct: 134 YAQSMELYNKALEKGIAKECARFILPL-----STPTTIYMSGTIRDWIHYIELRTSNGTQ 188 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.122 0.331 Lambda K H 0.267 0.0377 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,476,673 Number of Sequences: 36641 Number of extensions: 740698 Number of successful extensions: 2337 Number of sequences better than 10.0: 44 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 2176 Number of HSP's gapped (non-prelim): 132 length of query: 544 length of database: 10,336,785 effective HSP length: 102 effective length of query: 442 effective length of database: 6,599,403 effective search space: 2916936126 effective search space used: 2916936126 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 61 (28.2 bits)