BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q03611 (733 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5H3O-A nrPDB 1525 0.0 6CJQ-A nrPDB 159 5e-39 5U6P-A nrPDB 150 1e-36 5V4S-A nrPDB 145 7e-35 5VA1-A nrPDB 142 4e-34 5K7L-A nrPDB 130 3e-30 3UKN-A nrPDB 87 2e-17 4L11-A nrPDB 79 5e-15 5JON-A nrPDB 74 2e-13 4F8A-A nrPDB 57 2e-08 2N7G-A nrPDB 55 1e-07 4CHV-A nrPDB 46 6e-05 6BQ8-A nrPDB 45 1e-04 5FET-A nrPDB 43 6e-04 3I59-A nrPDB 42 8e-04 5J3U-A nrPDB 41 0.002 5DYK-A nrPDB 41 0.002 4EV0-A nrPDB 40 0.003 4ORF-A nrPDB 40 0.004 6FTF-B nrPDB 39 0.008 2XKO-A nrPDB 39 0.009 4CYD-A nrPDB 38 0.015 5JAX-A nrPDB 38 0.017 4QX5-A nrPDB 38 0.017 4Z07-A nrPDB 38 0.018 3SWF-A nrPDB 38 0.019 3SHR-A nrPDB 38 0.019 4AVC-A nrPDB 36 0.054 4MGY-E nrPDB 36 0.075 4F7Z-A nrPDB 35 0.090 5KBF-A nrPDB 35 0.13 1O7F-A nrPDB 35 0.14 2OZ6-A nrPDB 33 0.57 6AIO-A nrPDB 31 2.4 6EAS-A nrPDB 30 3.2 4X6Q-B nrPDB 30 3.3 6BYS-B nrPDB 30 3.6 1CX4-A nrPDB 30 3.8 2QCS-B nrPDB 30 3.9 5XIX-A nrPDB 29 6.4 5T8N-A nrPDB 29 6.6 3J4Q-B nrPDB 29 7.2 2FSE-B nrPDB 29 8.5 2QVS-B nrPDB 28 9.8 >5H3O-A nrPDB Length = 738 Score = 1525 bits (3948), Expect = 0.0, Method: Compositional matrix adjust. Identities = 733/733 (100%), Positives = 733/733 (100%) Query: 1 MSTAEPAPDPTNPSTSGLAPTTNGIGSPPPTASAATKFSILTKFLRRKNQVHTTTAQQNE 60 MSTAEPAPDPTNPSTSGLAPTTNGIGSPPPTASAATKFSILTKFLRRKNQVHTTTAQQNE Sbjct: 6 MSTAEPAPDPTNPSTSGLAPTTNGIGSPPPTASAATKFSILTKFLRRKNQVHTTTAQQNE 65 Query: 61 FMQKYMPNGNSNAVQPAATGGQPASSDGGSAIEVPPPKESYAVRIRKYLANYTQDPSTDN 120 FMQKYMPNGNSNAVQPAATGGQPASSDGGSAIEVPPPKESYAVRIRKYLANYTQDPSTDN Sbjct: 66 FMQKYMPNGNSNAVQPAATGGQPASSDGGSAIEVPPPKESYAVRIRKYLANYTQDPSTDN 125 Query: 121 FYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNGTLNSTTQVECTYNMLTNM 180 FYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNGTLNSTTQVECTYNMLTNM Sbjct: 126 FYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNGTLNSTTQVECTYNMLTNM 185 Query: 181 KEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKV 240 KEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKV Sbjct: 186 KEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKV 245 Query: 241 TKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETR 300 TKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETR Sbjct: 246 TKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETR 305 Query: 301 SSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLL 360 SSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLL Sbjct: 306 SSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLL 365 Query: 361 RRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAA 420 RRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAA Sbjct: 366 RRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAA 425 Query: 421 RTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIA 480 RTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIA Sbjct: 426 RTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIA 485 Query: 481 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV 540 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV Sbjct: 486 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV 545 Query: 541 VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALR 600 VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALR Sbjct: 546 VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALR 605 Query: 601 EYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAEHLNNAVKVLQTRMARLIVEHS 660 EYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAEHLNNAVKVLQTRMARLIVEHS Sbjct: 606 EYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAEHLNNAVKVLQTRMARLIVEHS 665 Query: 661 STEGKLMKRIEMLEKHLSRYKALARRQKTMHGVSIDGGDISTDGVDERVRPPRLRQTKTI 720 STEGKLMKRIEMLEKHLSRYKALARRQKTMHGVSIDGGDISTDGVDERVRPPRLRQTKTI Sbjct: 666 STEGKLMKRIEMLEKHLSRYKALARRQKTMHGVSIDGGDISTDGVDERVRPPRLRQTKTI 725 Query: 721 DLPTGTESESLLK 733 DLPTGTESESLLK Sbjct: 726 DLPTGTESESLLK 738 >6CJQ-A nrPDB Length = 456 Score = 159 bits (401), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 85/304 (27%), Positives = 165/304 (54%), Gaps = 32/304 (10%) Query: 304 PNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRY 363 P R++ +V +I++ H AC G ++ Q ++ T RY Sbjct: 151 PALLRLLSLVGFILLAAHGIAC------------------GWMSLQPPSENPAGT---RY 189 Query: 364 VYSFYWSTLILTTIGE---VPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAA 420 + +FYW+ LTTIG PS Y V ++L+ G ++ ++GN+ S++S + AA Sbjct: 190 LSAFYWTITTLTTIGYGDITPSTPTQTVYTIV-IELL-GAAMYGLVIGNIASLVSKLDAA 247 Query: 421 RTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIA 480 + + +++ + ++ +++S +L+ R+I++FDYLW ++ +++VLK LP L+ +A Sbjct: 248 KLLHRERVERVTAFLSYKRISPELQRRIIEYFDYLWETRRGYEEREVLKELPHPLRLAVA 307 Query: 481 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV 540 M++H + + KV +F+ + +++L L+ ++ PG++I + G++G ++Y + RG ++V Sbjct: 308 MEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIYGPGEYIIRAGEMGSDVYFINRGSVEV 367 Query: 541 VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALR 600 + D K + L EG FGE++++ A RTA VR+ + DL+ L K L Sbjct: 368 LSADEKTRYAILSEGQFFGEMALILRAP------RTATVRARAFCDLYRLDKETFDRILS 421 Query: 601 EYPD 604 YP+ Sbjct: 422 RYPE 425 >5U6P-A nrPDB Length = 660 Score = 150 bits (380), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 105/427 (24%), Positives = 205/427 (48%), Gaps = 43/427 (10%) Query: 204 WVFFDLLMDCVYLIDTFLNYRMGYM--DQGLVVREAEKVTKAYWQSKQYRIDGISLIPLD 261 W+ F++ D V+L+D +N+R G + D ++ + KV K + + +D IS IP+D Sbjct: 175 WIIFNVASDTVFLLDLIMNFRTGTVNEDSSEIILDP-KVIKMNYLKSWFVVDFISSIPVD 233 Query: 262 YILGWPIPYINWRGLPILRLNRLIRYKR----------------VRNCLERTETRSSMPN 305 YI ++ R R++R+ + + E + + Sbjct: 234 YIFLIVEKGMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLAS 293 Query: 306 A-FRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYV 364 A R+ ++ ++++ HW+ CL F + D WV SL + + D+ ++Y Sbjct: 294 AVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWV-------SLNEMVNDSWGKQYS 346 Query: 365 YSFYWSTLILTTIG-EVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTE 423 Y+ + + + IG +PV + L ++ G +A VG+ ++I ++ ++R + Sbjct: 347 YALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQ 406 Query: 424 FQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQV 483 +Q K ++QYM K+ + ++ ++++ + K ++ +L L D L+ EI V Sbjct: 407 YQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGK-IFDEENILNELNDPLREEI---V 462 Query: 484 HFETLRKVR---IFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV 540 +F + V +F + + + ++ KL+ +VF PGD+I ++G +G++MY ++ G V Sbjct: 463 NFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGV 522 Query: 541 VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALR 600 + K+ + L +GS FGE+ +L RRTA+VR+ Y L+ LS + L Sbjct: 523 ITKSSKE--MKLTDGSYFGEICLL------TKGRRTASVRADTYCRLYSLSVDNFNEVLE 574 Query: 601 EYPDARK 607 EYP R+ Sbjct: 575 EYPMMRR 581 >5V4S-A nrPDB Length = 465 Score = 145 bits (366), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 102/411 (24%), Positives = 196/411 (47%), Gaps = 48/411 (11%) Query: 209 LLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDY----IL 264 +D V+ +D N G + +V K Y S + ID I+ +PL+Y I Sbjct: 77 FFIDFVFALDILWNCFTPEYKDGKWILTRSQVIKDYLGS-WFIIDLIAALPLEYATTTIF 135 Query: 265 G-----WPIPYINWRGLPILRLNRLIRYKRVRNCLERTE-TRSSMPNAFRVVVVVWYIVI 318 G +P Y+ +L + R+++ R+ + L+R P R+V+ ++ + Sbjct: 136 GLQQSQYPYLYL------LLGVTRILKVFRISDILQRINLAFQPTPGILRLVLFAFWATL 189 Query: 319 IIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITD--TLLRRYVYSFYWSTLILTT 376 + HW A W+Y DD+ D T Y+ + YW+ + T Sbjct: 190 VAHWCAV--------------GWLY--------VDDLLDYQTGWSEYIIALYWTVATIAT 227 Query: 377 IGEVP-SPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYM 435 +G +P + + + ++ G ++AT++GN+ S++ ++ A+ + KM + ++ Sbjct: 228 VGYGDITPSTDSQRIYTIFVMILGAGVYATVIGNIASILGSLDLAKAAQRKKMAQVDSFL 287 Query: 436 ELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQ 495 + R +S+ + RV ++ Y+ + +L LP L+ E+ +Q+H + L KV + Sbjct: 288 KARNISQNIRRRVRDYYMYIIDRGWGEDENALLNDLPISLRREVKIQLHRDLLEKVPFLK 347 Query: 496 DCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEG 555 + L+ LV ++ +F GD I ++G+ G ++YI+ G + ++D D K + ++LQEG Sbjct: 348 GADPALVTSLVFSMKPMIFLEGDTIFRRGEKGDDLYILSEGSVDILDSDEKTILLSLQEG 407 Query: 556 SVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDAR 606 FGEL+++ A R+A VR+ +++ LSKTD N L+ + R Sbjct: 408 QFFGELALVMDAP------RSATVRATTTCEIYTLSKTDFDNVLKRFSQFR 452 >5VA1-A nrPDB Length = 795 Score = 142 bits (359), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 100/407 (24%), Positives = 199/407 (48%), Gaps = 25/407 (6%) Query: 208 DLLMDCVYLIDTFLNYRMGYMDQGL-VVREAEKVTKAYWQSKQYRIDGISLIPLDYILGW 266 DL++D ++++D +N+R Y++ VV ++ Y++ + ID ++ IP D ++ Sbjct: 216 DLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKG-WFLIDMVAAIPFDLLI-- 272 Query: 267 PIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACL 326 + + +L+ RL+R RV R R S A + +++ +I HW AC+ Sbjct: 273 -FGSGSEELIGLLKTARLLRLVRV----ARKLDRYSEYGAAVLFLLMCTFALIAHWLACI 327 Query: 327 YFWISEWIGLGTDA---WVYGHLNKQSLPDDITD----TLLRRYVYSFYWSTLILTTIG- 378 ++ I D+ W++ ++ P + + ++ +YV + Y++ LT++G Sbjct: 328 WYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGF 387 Query: 379 EVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELR 438 SP N E F ++ G L++A+I GNV ++I + + + +M +++++ Sbjct: 388 GNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFH 447 Query: 439 KVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCE 498 ++ L R+ ++F + W+ + VLK P+ LQA+I + ++ L+ + F+ Sbjct: 448 QIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGAT 507 Query: 499 AGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVF 558 G L L +K + PGD + GD+ +Y + RG ++++ G V L + +F Sbjct: 508 KGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEIL--RGDVVVAILGKNDIF 565 Query: 559 GE-LSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPD 604 GE L++ G NG +VR++ Y DL + + DL L YP+ Sbjct: 566 GEPLNLYARPGKSNG-----DVRALTYCDLHKIHRDDLLEVLDMYPE 607 >5K7L-A nrPDB Length = 857 Score = 130 bits (326), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 101/418 (24%), Positives = 190/418 (45%), Gaps = 29/418 (6%) Query: 204 WVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYI 263 W+ D ++D ++L+D LN+ ++ V K+ + + + ID +S +P D I Sbjct: 250 WLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVI 309 Query: 264 LGWPIPYINWRGL-PILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHW 322 + L L++ RL+R RV L+ A +V++V + HW Sbjct: 310 NAFENVDEGISSLFSSLKVVRLLRLGRVARKLDHYIEY----GAAVLVLLVCVFGLAAHW 365 Query: 323 NACLYFWISEWIGLGTD-------AWVYGHLNKQSLPDDITDTLLRR----------YVY 365 AC+++ I ++ D +W+Y P + + Y+ Sbjct: 366 MACIWYSIGDYEIFDEDTKTIRNNSWLYQLALDIGTPYQFNGSGSGKWEGGPSKNSVYIS 425 Query: 366 SFYWSTLILTTIG-EVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEF 424 S Y++ LT++G +P +IE F +M G L++ATI GNV ++ M A + Sbjct: 426 SLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRY 485 Query: 425 QNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVH 484 ++ ++ +++L +V K L RV+ + W+ + + ++VL++ P ++A+I + ++ Sbjct: 486 HEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLN 545 Query: 485 FETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDD 544 + ++ F+ G L L ++ Q +PGD I G+ + V G L+V+ DD Sbjct: 546 RKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDD 605 Query: 545 GKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREY 602 +V L +G VFG++ + ANVR++ Y DL V+ + L L Y Sbjct: 606 --EVVAILGKGDVFGDV----FWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFY 657 >3UKN-A nrPDB Length = 212 Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 53/194 (27%), Positives = 103/194 (53%), Gaps = 7/194 (3%) Query: 411 GSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKV 470 G+M M + R+ + + +K ++ + ++ K L R+++ F W+ + ++LK Sbjct: 1 GAMDQRMYSRRSLYHTRTKDLKDFIRVHRLPKALAQRMLECFQTTWSVNNGIDVSELLKD 60 Query: 471 LPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREM 530 PD+L+A+IAM ++ E L ++ +F+ G L L L ++ +PG+F+ ++GD + + Sbjct: 61 FPDELRADIAMHLNKELL-QLPLFESASRGCLRSLSLIIKTSFCAPGEFLIRQGDALQAI 119 Query: 531 YIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVL 590 Y V G ++V+ D+ V L +G + G S+ + + ANV+++ Y DL + Sbjct: 120 YFVCSGSMEVLKDN--TVLAILGKGDLIGSDSLTK----EQVIKTNANVKALTYCDLQYI 173 Query: 591 SKTDLWNALREYPD 604 S L LR YP+ Sbjct: 174 SLKGLREVLRLYPE 187 >4L11-A nrPDB Length = 204 Score = 79.3 bits (194), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 48/188 (25%), Positives = 92/188 (48%), Gaps = 6/188 (3%) Query: 417 MSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQ 476 M + + +M +++++ ++ L R+ ++F + WT + VLK P+ LQ Sbjct: 3 MGSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNSVLKGFPECLQ 62 Query: 477 AEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRG 536 A+I + ++ L F+ G L L LK + PGD + KGD+ +Y + RG Sbjct: 63 ADICLHLNRNLLNNCSAFEAASPGCLRALSLKFKTTHAPPGDILVHKGDVLTYLYFIARG 122 Query: 537 RLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLW 596 ++++ DD V L + +FGE ++ K+ +NV+++ Y DL + + DL Sbjct: 123 SIEILKDD--VVMAILGKDDIFGENPCIHSTLGKS----NSNVKALTYCDLHKIHRDDLL 176 Query: 597 NALREYPD 604 + L +P+ Sbjct: 177 DVLDLFPE 184 >5JON-A nrPDB Length = 517 Score = 74.3 bits (181), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 39/115 (33%), Positives = 66/115 (57%), Gaps = 8/115 (6%) Query: 493 IFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTL 552 +F + + + ++ KL+ +VF PGD+I ++G IG++MY ++ G + V+ K+ + L Sbjct: 394 LFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE--MKL 451 Query: 553 QEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARK 607 +GS FGE+ +L RRTA+VR+ Y L+ LS + L EYP R+ Sbjct: 452 SDGSYFGEICLLTRG------RRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 500 >4F8A-A nrPDB Length = 160 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 38/138 (27%), Positives = 70/138 (50%), Gaps = 6/138 (4%) Query: 465 QQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKG 524 ++VL++ P ++A+I + ++ + ++ F+ G L L ++ Q +PGD I G Sbjct: 6 EKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAG 65 Query: 525 DIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGY 584 + + V G L+V+ DD +V L +G VFG++ +++ ANVR++ Y Sbjct: 66 ESVDSLCFVVSGSLEVIQDD--EVVAILGKGDVFGDVFWKEATLAQS----CANVRALTY 119 Query: 585 TDLFVLSKTDLWNALREY 602 DL V+ + L L Y Sbjct: 120 CDLHVIKRDALQKVLEFY 137 >2N7G-A nrPDB Length = 154 Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 12/128 (9%) Query: 482 QVHFETLRKV----RIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGR 537 ++F+++R + + F+ G L L +K + PGD + GD+ +Y + RG Sbjct: 17 NLYFQSMRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGS 76 Query: 538 LQVVDDDGKKVFVTLQEGSVFGE-LSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLW 596 ++++ G V L + +FGE L++ G NG +VR++ Y DL + + DL Sbjct: 77 IEIL--RGDVVVAILGKNDIFGEPLNLYARPGKSNG-----DVRALTYCDLHKIHRDDLL 129 Query: 597 NALREYPD 604 L YP+ Sbjct: 130 EVLDMYPE 137 >4CHV-A nrPDB Length = 361 Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 10/112 (8%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 +++ + V +FQ +L E+V L+ + G IC+ G+ G M+ V G + V Sbjct: 226 NWQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVVEGSVSVATP 285 Query: 544 DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDL 595 + V L G+ FGE++++ +G R+A V + L L D Sbjct: 286 NP----VELGPGAFFGEMALI------SGEPRSATVSAATTVSLLSLHSADF 327 >6BQ8-A nrPDB Length = 152 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 54/96 (56%), Gaps = 10/96 (10%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD---- 543 LR V + ++ L +++ L+++ + GD+I ++G+ G +I+ +G+++V Sbjct: 15 LRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGH 74 Query: 544 DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANV 579 D ++ TLQ+G FGE +++ + + R+AN+ Sbjct: 75 DQPQLIKTLQKGEYFGEKALI------SDDVRSANI 104 >5FET-A nrPDB Length = 847 Score = 42.7 bits (99), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 22/54 (40%), Positives = 34/54 (62%), Gaps = 2/54 (3%) Query: 511 LQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSIL 564 +Q+F PG+ I K+GD G ++I+K G+ V +D K L +GS FGE ++L Sbjct: 188 IQMFKPGETIVKQGDYGDVLFILKEGKATVFIND--KEIRVLNKGSYFGERALL 239 Score = 37.4 bits (85), Expect = 0.023, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 35/57 (61%), Gaps = 2/57 (3%) Query: 509 LQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILN 565 +Q VF GD + K+G+ G +I+ G+ V +D KKV ++ +GS FGE ++++ Sbjct: 68 MQFFVFKGGDLVIKQGEKGSYFFIINSGKFDVYVND-KKV-KSMGKGSSFGEAALIH 122 Score = 37.0 bits (84), Expect = 0.029, Method: Compositional matrix adjust. Identities = 22/77 (28%), Positives = 43/77 (55%), Gaps = 2/77 (2%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKK 547 ++K+ IF+ L+ + + GD+I ++G++G YI+K G ++V +GK+ Sbjct: 407 IKKMYIFRYLSEQQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEVT-KNGKR 465 Query: 548 VFVTLQEGSVFGELSIL 564 + TL + FGE ++L Sbjct: 466 L-RTLGKNDYFGERALL 481 >3I59-A nrPDB Length = 249 Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 4/105 (3%) Query: 482 QVHF-ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV 540 Q H E L + IFQ E +A L +LQ F G + +G+ G +YI+ G++++ Sbjct: 23 QSHMDEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKI 82 Query: 541 --VDDDGKKVFVTLQEGS-VFGELSILNIAGSKNGNRRTANVRSV 582 DG++ +T+ S +FGELSI + + VR+V Sbjct: 83 GRRAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAV 127 >5J3U-A nrPDB Length = 261 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 9/114 (7%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVD--DDG 545 LR+ +F + L ++L +Q + + ++GD G +YIV+ G L D Sbjct: 16 LRQSFLFNSLDEKDLNTVILAMQEKKIEASTCLIREGDDGECLYIVQSGELNCSKLIDGE 75 Query: 546 KKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 ++V + G FGEL++L A R A V SV DL+ L + D +NA+ Sbjct: 76 ERVVKVVGPGDAFGELALLYNA------PRAATVTSVSACDLWELGR-DTFNAI 122 >5DYK-A nrPDB Length = 853 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 8/80 (10%) Query: 488 LRKVRIFQ---DCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDD 544 ++K+ IF+ D + LL E + + GD+I ++G++G YI+K G +++V + Sbjct: 413 IKKMYIFRYLTDKQCNLLIE---AFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIVKN- 468 Query: 545 GKKVFVTLQEGSVFGELSIL 564 KK TL + FGE ++L Sbjct: 469 -KKRLRTLGKNDYFGERALL 487 Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust. Identities = 22/55 (40%), Positives = 36/55 (65%), Gaps = 4/55 (7%) Query: 511 LQVFSPGDFICKKGDIGREMYIVKRGRLQV-VDDDGKKVFVTLQEGSVFGELSIL 564 +Q F G+ I K+GD G +YI+K G+ V ++D+ +V L++GS FGE ++L Sbjct: 194 IQNFKSGETIVKQGDYGDVLYILKEGKATVYINDEEIRV---LEKGSYFGERALL 245 >4EV0-A nrPDB Length = 216 Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 9/98 (9%) Query: 509 LQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDD---GKKVFVTLQEGSVFGELSILN 565 Q +++ G I +GD+G+ +Y+V G++++ ++ L G +FGE+S+L Sbjct: 22 FQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQERTLALLGPGELFGEMSLL- 80 Query: 566 IAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYP 603 + R+A+ +V T+L L + D +R P Sbjct: 81 -----DEGERSASAVAVEDTELLALFREDYLALIRRLP 113 >4ORF-A nrPDB Length = 340 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 2/88 (2%) Query: 482 QVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV 541 +V L + F C L L +L+ PG + ++GD +++ GR+QV Sbjct: 13 EVRAADLAALEFFTGCRPSALEPLATQLRPLKAEPGQVLIRQGDPALTFMLIESGRVQVS 72 Query: 542 D--DDGKKVFVTLQEGSVFGELSILNIA 567 DG + + ++ G + GE+++L A Sbjct: 73 HAVADGPPIVLDIEPGLIIGEIALLRDA 100 >6FTF-B nrPDB Length = 304 Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Query: 504 ELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV--DDDGKKVFVT-LQEGSVFGE 560 +L L + FSPG++I G+ G +YI+ G ++V+ D DG+ V +G GE Sbjct: 176 QLADALSSEEFSPGEYIIHYGEEGEWLYIIMEGTVEVIGRDADGEPTKVCEFTQGDHIGE 235 Query: 561 LSILN 565 L LN Sbjct: 236 LEFLN 240 >2XKO-A nrPDB Length = 222 Score = 38.5 bits (88), Expect = 0.009, Method: Compositional matrix adjust. Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 11/109 (10%) Query: 507 LKLQLQVFSPGDFICKKGDIGREMYIVKRG--RLQVVDDDGKKVFVT-LQEGSVFGELSI 563 L LQ++ F G I GD +Y++ +G +L V + G+++ V L+E SVFG LS+ Sbjct: 20 LPLQIEQFERGKTIFFPGDPAERVYLLVKGAVKLSRVYESGEEITVALLRENSVFGVLSL 79 Query: 564 LNIAGSKNGNRRTANVRSVGYT--DLFVLSKTDLWNALREYPDARKLLL 610 L G R +V +T LF + + AL E P+ ++L Sbjct: 80 L------TGQRSDRFYHAVAFTPVQLFSVPIEFMQKALIERPELANVML 122 >4CYD-A nrPDB Length = 225 Score = 38.1 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 3/83 (3%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD-- 543 E L + IFQ + + L+ ++ F G I +G+ G +YI+ G++++ Sbjct: 4 EILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARHAP 63 Query: 544 DGKKVFVTLQEGS-VFGELSILN 565 DG++ +T+ S +FGELSI + Sbjct: 64 DGRENLLTIMGPSDMFGELSIFD 86 >5JAX-A nrPDB Length = 135 Score = 37.7 bits (86), Expect = 0.017, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 51/100 (51%), Gaps = 10/100 (10%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + E L+ V FQ +L++L L+ + G++I ++G G +I+ +G + V + Sbjct: 11 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 70 Query: 544 DGKK---VFV-TLQEGSVFGELSILNIAGSKNGNRRTANV 579 D VF+ TL +G FGE ++ + + RTANV Sbjct: 71 DSPSEDPVFLRTLGKGDWFGEKAL------QGEDVRTANV 104 >4QX5-A nrPDB Length = 153 Score = 37.7 bits (86), Expect = 0.017, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 51/100 (51%), Gaps = 10/100 (10%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + E L+ V FQ +L++L L+ + G++I ++G G +I+ +G + V + Sbjct: 11 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 70 Query: 544 DGKK---VFV-TLQEGSVFGELSILNIAGSKNGNRRTANV 579 D VF+ TL +G FGE ++ + + RTANV Sbjct: 71 DSPSEDPVFLRTLGKGDWFGEKAL------QGEDVRTANV 104 >4Z07-A nrPDB Length = 262 Score = 37.7 bits (86), Expect = 0.018, Method: Compositional matrix adjust. Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 10/113 (8%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + E L+ V FQ +L++L L+ + G++I ++G G +I+ +G + V + Sbjct: 138 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 197 Query: 544 DGKK---VFV-TLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSK 592 D VF+ TL +G FGE ++ + + RTANV + V+ + Sbjct: 198 DSPSEDPVFLRTLGKGDWFGEKAL------QGEDVRTANVIAAEAVTCLVIDR 244 Score = 37.0 bits (84), Expect = 0.031, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 37/63 (58%), Gaps = 8/63 (12%) Query: 520 ICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANV 579 I K+GD+G +Y+++ G+++V + K T+ G VFGEL+IL RTA V Sbjct: 56 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL------YNCTRTATV 107 Query: 580 RSV 582 +++ Sbjct: 108 KTL 110 >3SWF-A nrPDB Length = 74 Score = 37.7 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 17/44 (38%), Positives = 29/44 (65%) Query: 634 VEEIAEHLNNAVKVLQTRMARLIVEHSSTEGKLMKRIEMLEKHL 677 +EE + ++V +LQTR AR++ E+ S + KL +R+ +EK L Sbjct: 5 LEEKVTRMESSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFL 48 >3SHR-A nrPDB Length = 299 Score = 37.7 bits (86), Expect = 0.019, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 10/100 (10%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + E L+ V FQ +L++L L+ + G++I ++G G +I+ +G++ V + Sbjct: 155 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGKVNVTRE 214 Query: 544 DGKK---VFV-TLQEGSVFGELSILNIAGSKNGNRRTANV 579 D VF+ TL +G FGE ++ + + RTANV Sbjct: 215 DSPNEDPVFLRTLGKGDWFGEKAL------QGEDVRTANV 248 Score = 36.2 bits (82), Expect = 0.051, Method: Compositional matrix adjust. Identities = 18/45 (40%), Positives = 30/45 (66%), Gaps = 2/45 (4%) Query: 520 ICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSIL 564 I K+GD+G +Y+++ G+++V + K T+ G VFGEL+IL Sbjct: 73 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 115 >4AVC-A nrPDB Length = 333 Score = 36.2 bits (82), Expect = 0.054, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV--VDD 543 E L + +FQ C A L L +Q + G + ++G+ ++ G +V V D Sbjct: 13 EDLAGMDVFQGCPAEGLVSLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEVSHVGD 72 Query: 544 DGKKVFVTLQEGSVFGELSILN 565 DG + G + GE+++L Sbjct: 73 DGVAIIARALPGMIVGEIALLR 94 >4MGY-E nrPDB Length = 694 Score = 35.8 bits (81), Expect = 0.075, Method: Compositional matrix adjust. Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Query: 517 GDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIA 567 G + +G+ G YI+ +G + VV GK V TL EG FG+L+++N A Sbjct: 64 GTVLFNQGEEGTSWYIILKGSVNVVIY-GKGVVCTLHEGDDFGQLALVNDA 113 >4F7Z-A nrPDB Length = 999 Score = 35.4 bits (80), Expect = 0.090, Method: Compositional matrix adjust. Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Query: 517 GDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIA 567 G + +G+ G YI+ +G + VV GK V TL EG FG+L+++N A Sbjct: 369 GTVLFNQGEEGTSWYIILKGSVNVVIY-GKGVVCTLHEGDDFGKLALVNDA 418 >5KBF-A nrPDB Length = 301 Score = 35.0 bits (79), Expect = 0.13, Method: Compositional matrix adjust. Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 22/123 (17%) Query: 520 ICKKGDIGREMYIVKRGRLQVV---DDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRT 576 I +GD G +Y++ +G +++ +++ K+V L+ VFGEL++L SK T Sbjct: 76 IINEGDYGDLLYVIDQGEVEIYKTKENNKKEVLTVLKSKDVFGELALL--YNSKRAATAT 133 Query: 577 ANVRSVGYTDLFVLSKTDLWNALRE-YPDARKLLLAKGR----EILKKDNLLDENAPEEQ 631 A L+K LW RE + K ++AK R +IL N+L + P E+ Sbjct: 134 A------------LTKCHLWALDRESFTYIIKDMVAKKRKMYEDILSHVNILKDMDPYER 181 Query: 632 KTV 634 V Sbjct: 182 CKV 184 >1O7F-A nrPDB Length = 469 Score = 34.7 bits (78), Expect = 0.14, Method: Compositional matrix adjust. Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Query: 517 GDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIA 567 G + +G+ G YI+ +G + VV GK V TL EG FG+L+++N A Sbjct: 369 GTVLFNQGEEGTSWYIILKGSVNVVIY-GKGVVCTLHEGDDFGKLALVNDA 418 >2OZ6-A nrPDB Length = 207 Score = 32.7 bits (73), Expect = 0.57, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 5/83 (6%) Query: 502 LAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV--DDDGKKVFVT-LQEGSVF 558 L +L+ + ++ I GD ++ + +G + ++ DDDG+++ + L G F Sbjct: 6 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 65 Query: 559 GELSILNIAGSKNGNRRTANVRS 581 GEL + GS+ R+A VR+ Sbjct: 66 GELGLFEKEGSE--QERSAWVRA 86 >6AIO-A nrPDB Length = 418 Score = 30.8 bits (68), Expect = 2.4, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 14 STSGLAPTTNGIGSPPPTASAATKFSILTKFLRR 47 S SG++P+ + PPTA+A +F +L +R Sbjct: 43 SESGVSPSPRAVAYMPPTAAALDRFGLLDDIRKR 76 >6EAS-A nrPDB Length = 308 Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust. Identities = 33/109 (30%), Positives = 50/109 (45%), Gaps = 15/109 (13%) Query: 141 ARQVFNDLIGPSSQSLCRFYNGTLNSTTQVECTYNMLTNMKE--MPTYSQYPD--LGWSK 196 A + F+++IG S S C Y GTL+S ++ +++T+ K+ SQY SK Sbjct: 40 ACEDFSNIIG--STSTCMLYKGTLSSGVEIAVASSLVTSAKDWSKENESQYRKKITNLSK 97 Query: 197 YWHFRMLWVFFDLLMDC-----VYLIDTFLNYRMGYMDQGLVVREAEKV 240 H F +LL C + F G + + L VREAEK+ Sbjct: 98 VSHKN----FMNLLGYCEEEHPFTRVMVFEYAPNGTLFEHLHVREAEKL 142 >4X6Q-B nrPDB Length = 416 Score = 30.0 bits (66), Expect = 3.3, Method: Compositional matrix adjust. Identities = 18/82 (21%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV---VD 542 E + + +F++ + +++++ + ++ G+ + +GD G Y++ RG + D Sbjct: 145 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 204 Query: 543 DDGKKVFVTLQEGSVFGELSIL 564 G+ V GS FGEL+++ Sbjct: 205 GVGRCVGNYDNRGS-FGELALM 225 Score = 28.5 bits (62), Expect = 9.6, Method: Compositional matrix adjust. Identities = 15/62 (24%), Positives = 32/62 (51%), Gaps = 9/62 (14%) Query: 512 QVFSPGDFICKKGDIGREMYIVKRGRLQV---------VDDDGKKVFVTLQEGSVFGELS 562 +V++ G+ I +GD+ +IV+ G +++ V+++G G FGEL+ Sbjct: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELA 352 Query: 563 IL 564 ++ Sbjct: 353 LV 354 >6BYS-B nrPDB Length = 379 Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 8/68 (11%) Query: 514 FSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGN 573 F G+ + ++GD G Y++ +G + V ++ + ++ EG FGEL+++ G Sbjct: 156 FIAGETVIQQGDEGDNFYVIDQGEMDVYVNN--EWATSVGEGGSFGELALI------YGT 207 Query: 574 RRTANVRS 581 R A V++ Sbjct: 208 PRAATVKA 215 >1CX4-A nrPDB Length = 305 Score = 30.0 bits (66), Expect = 3.8, Method: Compositional matrix adjust. Identities = 18/82 (21%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV---VD 542 E + + +F++ + +++++ + ++ G+ + +GD G Y++ RG + D Sbjct: 34 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 93 Query: 543 DDGKKVFVTLQEGSVFGELSIL 564 G+ V GS FGEL+++ Sbjct: 94 GVGRCVGNYDNRGS-FGELALM 114 >2QCS-B nrPDB Length = 291 Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 8/68 (11%) Query: 514 FSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGN 573 F G+ + ++GD G Y++ +G + V ++ + ++ EG FGEL+++ G Sbjct: 67 FIAGETVIQQGDEGDNFYVIDQGEMDVYVNN--EWATSVGEGGSFGELALI------YGT 118 Query: 574 RRTANVRS 581 R A V++ Sbjct: 119 PRAATVKA 126 >5XIX-A nrPDB Length = 472 Score = 29.3 bits (64), Expect = 6.4, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 21/43 (48%) Query: 135 NLLFVIARQVFNDLIGPSSQSLCRFYNGTLNSTTQVECTYNML 177 NL+F++ R L + LC+ YNG L ST Y ML Sbjct: 67 NLMFLVLRDGTGYLQCVLADELCQCYNGVLLSTESSVAVYGML 109 >5T8N-A nrPDB Length = 139 Score = 29.3 bits (64), Expect = 6.6, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 64/134 (47%), Gaps = 19/134 (14%) Query: 577 ANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEE 636 A VR + +L ++ L + + ++ L KG +++ K NA +++KT+E+ Sbjct: 11 AIVRLREHINLLSKKQSHLRTQITNQENEARIFLTKGNKVMAK------NALKKKKTIEQ 64 Query: 637 IAEHLNNAVKVLQTRMARLIVEHSSTEGKLMKRIEMLEKHLSRYKALARRQKTMH-GVSI 695 + + ++ ++ ++ +E ++ + M+ ++ A+ KT+H G+ I Sbjct: 65 LLSKVEGTMESMEQQL--FSIESANLNLETMRAMQ----------EGAKAMKTIHSGLDI 112 Query: 696 DGGDISTDGVDERV 709 D D + D + E+V Sbjct: 113 DKVDETMDEIREQV 126 >3J4Q-B nrPDB Length = 402 Score = 29.3 bits (64), Expect = 7.2, Method: Compositional matrix adjust. Identities = 17/82 (20%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV---D 542 E + + +F++ + L++++ + ++ + + +GD G Y+++RG ++ D Sbjct: 130 EACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKD 189 Query: 543 DDGKKVFVTLQEGSVFGELSIL 564 + + V GS FGEL+++ Sbjct: 190 NQTRSVGQYDNRGS-FGELALM 210 >2FSE-B nrPDB Length = 187 Score = 28.9 bits (63), Expect = 8.5, Method: Compositional matrix adjust. Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 10/93 (10%) Query: 157 CRFYNGTLNSTTQVECTYNMLTNMK---EMPTYSQYPDLGW--SKYWHFRMLWVFFDLLM 211 C F+NGT C YN +++ ++ Y +LG ++YW+ + DLL Sbjct: 12 CHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQK-----DLLE 66 Query: 212 DCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAY 244 +DT+ + G + V R E Y Sbjct: 67 QRRAAVDTYCRHNYGVGESFTVQRRVEPTVTVY 99 >2QVS-B nrPDB Length = 310 Score = 28.5 bits (62), Expect = 9.8, Method: Compositional matrix adjust. Identities = 17/82 (20%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV---D 542 E + + +F++ + L++++ + ++ + + +GD G Y+++RG ++ D Sbjct: 38 EACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKD 97 Query: 543 DDGKKVFVTLQEGSVFGELSIL 564 + + V GS FGEL+++ Sbjct: 98 NQTRSVGQYDNRGS-FGELALM 118 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5H3O-A nrPDB 1247 0.0 5VA1-A nrPDB 488 e-138 5K7L-A nrPDB 484 e-137 5U6P-A nrPDB 452 e-127 5V4S-A nrPDB 414 e-116 6CJQ-A nrPDB 325 5e-89 3UKN-A nrPDB 228 1e-59 4L11-A nrPDB 222 4e-58 4F8A-A nrPDB 172 4e-43 5JON-A nrPDB 152 5e-37 2N7G-A nrPDB 144 1e-34 5J3U-A nrPDB 112 6e-25 4CHV-A nrPDB 110 2e-24 3I59-A nrPDB 103 3e-22 6BQ8-A nrPDB 96 4e-20 5FET-A nrPDB 81 2e-15 Sequences not found previously or not previously below threshold: 4CYD-A nrPDB 89 9e-18 3SHR-A nrPDB 88 1e-17 5JAX-A nrPDB 87 2e-17 4Z07-A nrPDB 87 2e-17 4QX5-A nrPDB 87 2e-17 5DYK-A nrPDB 81 3e-15 5KBF-A nrPDB 79 7e-15 6BYS-B nrPDB 76 8e-14 2QCS-B nrPDB 76 8e-14 4EV0-A nrPDB 73 3e-13 4DIN-B nrPDB 72 1e-12 4ORF-A nrPDB 69 7e-12 6FTF-B nrPDB 66 8e-11 4I0B-A nrPDB 66 8e-11 3KCC-A nrPDB 66 8e-11 3J4Q-B nrPDB 62 1e-09 3E97-A nrPDB 62 1e-09 2QVS-B nrPDB 62 1e-09 4F7Z-A nrPDB 61 2e-09 1O7F-A nrPDB 61 2e-09 2OZ6-A nrPDB 60 4e-09 3IWZ-A nrPDB 59 7e-09 4MGY-E nrPDB 58 2e-08 1CX4-A nrPDB 57 2e-08 4X6Q-B nrPDB 57 3e-08 4AVC-A nrPDB 55 1e-07 3DKW-A nrPDB 54 3e-07 5W5B-A nrPDB 53 5e-07 2XKO-A nrPDB 52 1e-06 3LA7-A nrPDB 48 1e-05 1ZYB-A nrPDB 47 3e-05 2A79-B nrPDB 45 1e-04 4JTA-B nrPDB 45 1e-04 1ORQ-C nrPDB 43 4e-04 2A9H-A nrPDB 43 4e-04 2D93-A nrPDB 41 0.002 3B02-A nrPDB 40 0.002 4XDL-A nrPDB 40 0.003 4H33-A nrPDB 40 0.003 3RBZ-A nrPDB 40 0.003 3EFF-K nrPDB 40 0.004 1F6G-A nrPDB 39 0.006 3SWF-A nrPDB 39 0.007 2Q6A-A nrPDB 39 0.009 3VOU-A nrPDB 39 0.010 3PJS-K nrPDB 37 0.026 2GAU-A nrPDB 37 0.039 6CQ6-A nrPDB 36 0.057 4TWK-A nrPDB 36 0.057 5VMS-A nrPDB 35 0.080 3UM7-A nrPDB 35 0.093 3FB6-C nrPDB 35 0.13 4GX0-A nrPDB 34 0.20 5T8N-A nrPDB 34 0.23 2QKS-A nrPDB 34 0.34 2K1E-A nrPDB 33 0.44 1P7B-A nrPDB 33 0.51 3E6B-A nrPDB 32 0.66 3SYQ-A nrPDB 32 0.86 4L3I-A nrPDB 32 0.96 1NL3-A nrPDB 32 1.0 3UKM-A nrPDB 32 1.0 1JI6-A nrPDB 32 1.1 4Z80-A nrPDB 32 1.2 2H6C-A nrPDB 32 1.3 2CWD-A nrPDB 31 1.5 6AIO-A nrPDB 31 1.5 5FIL-H nrPDB 31 1.8 2W6I-H nrPDB 31 1.8 3RVY-A nrPDB 31 2.0 4RYU-A nrPDB 31 2.1 2NLJ-C nrPDB 31 2.2 2XSP-A nrPDB 30 2.4 5E44-A nrPDB 30 2.5 4QJ3-B nrPDB 30 2.5 3OHM-B nrPDB 30 2.5 4OB1-A nrPDB 30 2.6 6C96-A nrPDB 30 2.7 3SPG-A nrPDB 30 3.5 5M3Y-A nrPDB 30 3.8 3THY-A nrPDB 30 3.8 3ACP-A nrPDB 30 4.7 5XIX-A nrPDB 29 6.3 2E1D-A nrPDB 29 9.1 >5H3O-A nrPDB Length = 738 Score = 1247 bits (3227), Expect = 0.0, Method: Composition-based stats. Identities = 733/733 (100%), Positives = 733/733 (100%) Query: 1 MSTAEPAPDPTNPSTSGLAPTTNGIGSPPPTASAATKFSILTKFLRRKNQVHTTTAQQNE 60 MSTAEPAPDPTNPSTSGLAPTTNGIGSPPPTASAATKFSILTKFLRRKNQVHTTTAQQNE Sbjct: 6 MSTAEPAPDPTNPSTSGLAPTTNGIGSPPPTASAATKFSILTKFLRRKNQVHTTTAQQNE 65 Query: 61 FMQKYMPNGNSNAVQPAATGGQPASSDGGSAIEVPPPKESYAVRIRKYLANYTQDPSTDN 120 FMQKYMPNGNSNAVQPAATGGQPASSDGGSAIEVPPPKESYAVRIRKYLANYTQDPSTDN Sbjct: 66 FMQKYMPNGNSNAVQPAATGGQPASSDGGSAIEVPPPKESYAVRIRKYLANYTQDPSTDN 125 Query: 121 FYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNGTLNSTTQVECTYNMLTNM 180 FYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNGTLNSTTQVECTYNMLTNM Sbjct: 126 FYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNGTLNSTTQVECTYNMLTNM 185 Query: 181 KEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKV 240 KEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKV Sbjct: 186 KEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKV 245 Query: 241 TKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETR 300 TKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETR Sbjct: 246 TKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETR 305 Query: 301 SSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLL 360 SSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLL Sbjct: 306 SSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLL 365 Query: 361 RRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAA 420 RRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAA Sbjct: 366 RRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAA 425 Query: 421 RTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIA 480 RTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIA Sbjct: 426 RTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIA 485 Query: 481 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV 540 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV Sbjct: 486 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV 545 Query: 541 VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALR 600 VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALR Sbjct: 546 VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALR 605 Query: 601 EYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAEHLNNAVKVLQTRMARLIVEHS 660 EYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAEHLNNAVKVLQTRMARLIVEHS Sbjct: 606 EYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAEHLNNAVKVLQTRMARLIVEHS 665 Query: 661 STEGKLMKRIEMLEKHLSRYKALARRQKTMHGVSIDGGDISTDGVDERVRPPRLRQTKTI 720 STEGKLMKRIEMLEKHLSRYKALARRQKTMHGVSIDGGDISTDGVDERVRPPRLRQTKTI Sbjct: 666 STEGKLMKRIEMLEKHLSRYKALARRQKTMHGVSIDGGDISTDGVDERVRPPRLRQTKTI 725 Query: 721 DLPTGTESESLLK 733 DLPTGTESESLLK Sbjct: 726 DLPTGTESESLLK 738 >5VA1-A nrPDB Length = 795 Score = 488 bits (1257), Expect = e-138, Method: Composition-based stats. Identities = 100/410 (24%), Positives = 200/410 (48%), Gaps = 25/410 (6%) Query: 206 FFDLLMDCVYLIDTFLNYRMGYMDQGL-VVREAEKVTKAYWQSKQYRIDGISLIPLDYIL 264 DL++D ++++D +N+R Y++ VV ++ Y++ + ID ++ IP D ++ Sbjct: 214 VVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKG-WFLIDMVAAIPFDLLI 272 Query: 265 GWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNA 324 + + +L+ RL+R RV L+R S A + +++ +I HW A Sbjct: 273 ---FGSGSEELIGLLKTARLLRLVRVARKLDR----YSEYGAAVLFLLMCTFALIAHWLA 325 Query: 325 CLYFWISEWIGLGTDA---WVYGHLNKQSLPDDITD----TLLRRYVYSFYWSTLILTTI 377 C+++ I D+ W++ ++ P + + ++ +YV + Y++ LT++ Sbjct: 326 CIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSV 385 Query: 378 G-EVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYME 436 G SP N E F ++ G L++A+I GNV ++I + + + +M +++++ Sbjct: 386 GFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIR 445 Query: 437 LRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQD 496 ++ L R+ ++F + W+ + VLK P+ LQA+I + ++ L+ + F+ Sbjct: 446 FHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRG 505 Query: 497 CEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGS 556 G L L +K + PGD + GD+ +Y + RG ++++ G V L + Sbjct: 506 ATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEIL--RGDVVVAILGKND 563 Query: 557 VFGE-LSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDA 605 +FGE L++ G NG +VR++ Y DL + + DL L YP+ Sbjct: 564 IFGEPLNLYARPGKSNG-----DVRALTYCDLHKIHRDDLLEVLDMYPEF 608 >5K7L-A nrPDB Length = 857 Score = 484 bits (1246), Expect = e-137, Method: Composition-based stats. Identities = 109/456 (23%), Positives = 205/456 (44%), Gaps = 39/456 (8%) Query: 204 WVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYI 263 W+ D ++D ++L+D LN+ ++ V K+ + + + ID +S +P D I Sbjct: 250 WLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVI 309 Query: 264 LGWPIPYINWRGL-PILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHW 322 + L L++ RL+R RV L+ A +V++V + HW Sbjct: 310 NAFENVDEGISSLFSSLKVVRLLRLGRVARKLDHYIEY----GAAVLVLLVCVFGLAAHW 365 Query: 323 NACLYFWISEWIGLGTD-------AWVYGHLNKQSLPDDITDTLLRR----------YVY 365 AC+++ I ++ D +W+Y P + + Y+ Sbjct: 366 MACIWYSIGDYEIFDEDTKTIRNNSWLYQLALDIGTPYQFNGSGSGKWEGGPSKNSVYIS 425 Query: 366 SFYWSTLILTTIG-EVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEF 424 S Y++ LT++G +P +IE F +M G L++ATI GNV ++ M A + Sbjct: 426 SLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRY 485 Query: 425 QNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVH 484 ++ ++ +++L +V K L RV+ + W+ + + ++VL++ P ++A+I + ++ Sbjct: 486 HEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLN 545 Query: 485 FETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDD 544 + ++ F+ G L L ++ Q +PGD I G+ + V G L+V+ DD Sbjct: 546 RKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDD 605 Query: 545 GKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPD 604 +V L +G VFG++ + ANVR++ Y DL V+ + L L Y Sbjct: 606 --EVVAILGKGDVFGDV----FWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTA 659 Query: 605 A-----RKLLLA---KGREILKKDNLLDENAPEEQK 632 R L+L + R + +K + D EE++ Sbjct: 660 FSHSFSRNLILTYNLRKRIVFRK--ISDVKREEEER 693 >5U6P-A nrPDB Length = 660 Score = 452 bits (1162), Expect = e-127, Method: Composition-based stats. Identities = 101/423 (23%), Positives = 201/423 (47%), Gaps = 35/423 (8%) Query: 204 WVFFDLLMDCVYLIDTFLNYRMGYMD-QGLVVREAEKVTKAYWQSKQYRIDGISLIPLDY 262 W+ F++ D V+L+D +N+R G ++ + KV K + + +D IS IP+DY Sbjct: 175 WIIFNVASDTVFLLDLIMNFRTGTVNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDY 234 Query: 263 ILGWPIPYINWRGLPILRLNRLIRYKR----------------VRNCLERTETRSSMPNA 306 I ++ R R++R+ + + E + +A Sbjct: 235 IFLIVEKGMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASA 294 Query: 307 F-RVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVY 365 R+ ++ ++++ HW+ CL F + D WV SL + + D+ ++Y Y Sbjct: 295 VVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWV-------SLNEMVNDSWGKQYSY 347 Query: 366 SFYWSTLILTTIGEV-PSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEF 424 + + + + IG +PV + L ++ G +A VG+ ++I ++ ++R ++ Sbjct: 348 ALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQY 407 Query: 425 QNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVH 484 Q K ++QYM K+ + ++ ++++ + K ++ +L L D L+ EI Sbjct: 408 QEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGK-IFDEENILNELNDPLREEIVNFNC 466 Query: 485 FETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDD 544 + + + +F + + + ++ KL+ +VF PGD+I ++G +G++MY ++ G V+ Sbjct: 467 RKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKS 526 Query: 545 GKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPD 604 K+ + L +GS FGE+ +L RRTA+VR+ Y L+ LS + L EYP Sbjct: 527 SKE--MKLTDGSYFGEICLL------TKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPM 578 Query: 605 ARK 607 R+ Sbjct: 579 MRR 581 >5V4S-A nrPDB Length = 465 Score = 414 bits (1065), Expect = e-116, Method: Composition-based stats. Identities = 97/416 (23%), Positives = 195/416 (46%), Gaps = 44/416 (10%) Query: 202 MLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLD 261 +L +D V+ +D N G + +V K Y + ID I+ +PL+ Sbjct: 70 LLLTCIYFFIDFVFALDILWNCFTPEYKDGKWILTRSQVIKDY-LGSWFIIDLIAALPLE 128 Query: 262 Y----ILG-----WPIPYINWRGLPILRLNRLIRYKRVRNCLERTE-TRSSMPNAFRVVV 311 Y I G +P Y+ +L + R+++ R+ + L+R P R+V+ Sbjct: 129 YATTTIFGLQQSQYPYLYL------LLGVTRILKVFRISDILQRINLAFQPTPGILRLVL 182 Query: 312 VVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWST 371 ++ ++ HW A + ++ + + T Y+ + YW+ Sbjct: 183 FAFWATLVAHWCAVGWLYVDDLLDYQ--------------------TGWSEYIIALYWTV 222 Query: 372 LILTTIGEVP-SPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDG 430 + T+G +P + + + ++ G ++AT++GN+ S++ ++ A+ + KM Sbjct: 223 ATIATVGYGDITPSTDSQRIYTIFVMILGAGVYATVIGNIASILGSLDLAKAAQRKKMAQ 282 Query: 431 IKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRK 490 + +++ R +S+ + RV ++ Y+ + +L LP L+ E+ +Q+H + L K Sbjct: 283 VDSFLKARNISQNIRRRVRDYYMYIIDRGWGEDENALLNDLPISLRREVKIQLHRDLLEK 342 Query: 491 VRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFV 550 V + + L+ LV ++ +F GD I ++G+ G ++YI+ G + ++D D K + + Sbjct: 343 VPFLKGADPALVTSLVFSMKPMIFLEGDTIFRRGEKGDDLYILSEGSVDILDSDEKTILL 402 Query: 551 TLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDAR 606 +LQEG FGEL+++ A R+A VR+ +++ LSKTD N L+ + R Sbjct: 403 SLQEGQFFGELALVMDAP------RSATVRATTTCEIYTLSKTDFDNVLKRFSQFR 452 >6CJQ-A nrPDB Length = 456 Score = 325 bits (833), Expect = 5e-89, Method: Composition-based stats. Identities = 83/317 (26%), Positives = 167/317 (52%), Gaps = 28/317 (8%) Query: 290 VRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQ 349 V+ R + P R++ +V +I++ H AC G ++ Q Sbjct: 137 VQRSATRILSYRINPALLRLLSLVGFILLAAHGIAC------------------GWMSLQ 178 Query: 350 SLPDDITDTLLRRYVYSFYWSTLILTTIGEVP-SPVRNIEYAFVTLDLMCGVLIFATIVG 408 ++ T RY+ +FYW+ LTTIG +P + + + + G ++ ++G Sbjct: 179 PPSENPAGT---RYLSAFYWTITTLTTIGYGDITPSTPTQTVYTIVIELLGAAMYGLVIG 235 Query: 409 NVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVL 468 N+ S++S + AA+ + +++ + ++ +++S +L+ R+I++FDYLW ++ +++VL Sbjct: 236 NIASLVSKLDAAKLLHRERVERVTAFLSYKRISPELQRRIIEYFDYLWETRRGYEEREVL 295 Query: 469 KVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGR 528 K LP L+ +AM++H + + KV +F+ + +++L L+ ++ PG++I + G++G Sbjct: 296 KELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIYGPGEYIIRAGEMGS 355 Query: 529 EMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLF 588 ++Y + RG ++V+ D K + L EG FGE++++ A RTA VR+ + DL+ Sbjct: 356 DVYFINRGSVEVLSADEKTRYAILSEGQFFGEMALILRAP------RTATVRARAFCDLY 409 Query: 589 VLSKTDLWNALREYPDA 605 L K L YP+ Sbjct: 410 RLDKETFDRILSRYPEI 426 >3UKN-A nrPDB Length = 212 Score = 228 bits (580), Expect = 1e-59, Method: Composition-based stats. Identities = 53/202 (26%), Positives = 107/202 (52%), Gaps = 7/202 (3%) Query: 411 GSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKV 470 G+M M + R+ + + +K ++ + ++ K L R+++ F W+ + ++LK Sbjct: 1 GAMDQRMYSRRSLYHTRTKDLKDFIRVHRLPKALAQRMLECFQTTWSVNNGIDVSELLKD 60 Query: 471 LPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREM 530 PD+L+A+IAM ++ E L ++ +F+ G L L L ++ +PG+F+ ++GD + + Sbjct: 61 FPDELRADIAMHLNKELL-QLPLFESASRGCLRSLSLIIKTSFCAPGEFLIRQGDALQAI 119 Query: 531 YIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVL 590 Y V G ++V+ D+ V L +G + G S+ + + ANV+++ Y DL + Sbjct: 120 YFVCSGSMEVLKDN--TVLAILGKGDLIGSDSLT----KEQVIKTNANVKALTYCDLQYI 173 Query: 591 SKTDLWNALREYPDARKLLLAK 612 S L LR YP+ + +++ Sbjct: 174 SLKGLREVLRLYPEYAQKFVSE 195 >4L11-A nrPDB Length = 204 Score = 222 bits (566), Expect = 4e-58, Method: Composition-based stats. Identities = 48/191 (25%), Positives = 92/191 (48%), Gaps = 6/191 (3%) Query: 415 SNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDK 474 M + + +M +++++ ++ L R+ ++F + WT + VLK P+ Sbjct: 1 GAMGSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNSVLKGFPEC 60 Query: 475 LQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVK 534 LQA+I + ++ L F+ G L L LK + PGD + KGD+ +Y + Sbjct: 61 LQADICLHLNRNLLNNCSAFEAASPGCLRALSLKFKTTHAPPGDILVHKGDVLTYLYFIA 120 Query: 535 RGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTD 594 RG ++++ DD V L + +FGE ++ K+ +NV+++ Y DL + + D Sbjct: 121 RGSIEILKDD--VVMAILGKDDIFGENPCIHSTLGKS----NSNVKALTYCDLHKIHRDD 174 Query: 595 LWNALREYPDA 605 L + L +P+ Sbjct: 175 LLDVLDLFPEF 185 >4F8A-A nrPDB Length = 160 Score = 172 bits (437), Expect = 4e-43, Method: Composition-based stats. Identities = 41/152 (26%), Positives = 72/152 (47%), Gaps = 11/152 (7%) Query: 464 DQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKK 523 ++VL++ P ++A+I + ++ + ++ F+ G L L ++ Q +PGD I Sbjct: 5 TEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHA 64 Query: 524 GDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVG 583 G+ + V G L+V+ DD +V L +G VFG++ + ANVR++ Sbjct: 65 GESVDSLCFVVSGSLEVIQDD--EVVAILGKGDVFGDV----FWKEATLAQSCANVRALT 118 Query: 584 YTDLFVLSKTDLWNALREYPDA-----RKLLL 610 Y DL V+ + L L Y R L+L Sbjct: 119 YCDLHVIKRDALQKVLEFYTAFSHSFSRNLIL 150 >5JON-A nrPDB Length = 517 Score = 152 bits (384), Expect = 5e-37, Method: Composition-based stats. Identities = 43/138 (31%), Positives = 74/138 (53%), Gaps = 8/138 (5%) Query: 470 VLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGRE 529 L L+ EI + + + +F + + + ++ KL+ +VF PGD+I ++G IG++ Sbjct: 371 ELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKK 430 Query: 530 MYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFV 589 MY ++ G + V+ K+ + L +GS FGE+ +L RRTA+VR+ Y L+ Sbjct: 431 MYFIQHGVVSVLTKGNKE--MKLSDGSYFGEICLLTRG------RRTASVRADTYCRLYS 482 Query: 590 LSKTDLWNALREYPDARK 607 LS + L EYP R+ Sbjct: 483 LSVDNFNEVLEEYPMMRR 500 >2N7G-A nrPDB Length = 154 Score = 144 bits (363), Expect = 1e-34, Method: Composition-based stats. Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 8/130 (6%) Query: 477 AEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRG 536 + Q L+ + F+ G L L +K + PGD + GD+ +Y + RG Sbjct: 16 ENLYFQSMRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRG 75 Query: 537 RLQVVDDDGKKVFVTLQEGSVFGE-LSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDL 595 ++++ G V L + +FGE L++ G NG +VR++ Y DL + + DL Sbjct: 76 SIEIL--RGDVVVAILGKNDIFGEPLNLYARPGKSNG-----DVRALTYCDLHKIHRDDL 128 Query: 596 WNALREYPDA 605 L YP+ Sbjct: 129 LEVLDMYPEF 138 >5J3U-A nrPDB Length = 261 Score = 112 bits (280), Expect = 6e-25, Method: Composition-based stats. Identities = 36/140 (25%), Positives = 62/140 (44%), Gaps = 11/140 (7%) Query: 487 TLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVD--DD 544 LR+ +F + L ++L +Q + + ++GD G +YIV+ G L D Sbjct: 15 ILRQSFLFNSLDEKDLNTVILAMQEKKIEASTCLIREGDDGECLYIVQSGELNCSKLIDG 74 Query: 545 GKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPD 604 ++V + G FGEL++L A R A V SV DL+ L + +++ Sbjct: 75 EERVVKVVGPGDAFGELALLYNAP------RAATVTSVSACDLWELGRDTFNAIVKDAAT 128 Query: 605 ARKLLLAKGREILKKDNLLD 624 R+ + LK ++LD Sbjct: 129 KRRSMY---DSFLKSVHILD 145 Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 60/149 (40%), Gaps = 16/149 (10%) Query: 455 LWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVF 514 LW + + ++K K ++ ++ L+ V I +A ++ L+ ++F Sbjct: 111 LWELGRD-TFNAIVKDAATKRRS-----MYDSFLKSVHILDGMDAYERGKVADALRTEMF 164 Query: 515 SPGDFICKKGDIGREMYIVKRGRLQVVDD----DGKKVFVTLQEGSVFGELSILNIAGSK 570 + G +I ++G++G YIV+ G Q G FGEL+++ Sbjct: 165 TDGAYIVRQGELGDVFYIVEEGSAVATKSFGPGQPPIEVKKYQAGDYFGELALI------ 218 Query: 571 NGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 N R ANV + G + L + + Sbjct: 219 NEEPRAANVIAHGICKVACLERKSFKRLM 247 >4CHV-A nrPDB Length = 361 Score = 110 bits (276), Expect = 2e-24, Method: Composition-based stats. Identities = 44/252 (17%), Positives = 82/252 (32%), Gaps = 73/252 (28%) Query: 366 SFYWSTLILTTIGEVPS-PVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEF 424 + +W+ + L+T G + P +M G+ I G ++ A + Sbjct: 165 AMWWAVVTLSTTGYGDTIPQSFAGRVLAGAVMMSGIG----IFGLWAGIL-----ATGFY 215 Query: 425 QNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVH 484 Q G ++ + Sbjct: 216 QEVRRG--DFVR-----------------------------------------------N 226 Query: 485 FETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDD 544 ++ + V +FQ +L E+V L+ + G IC+ G+ G M+ V G + V + Sbjct: 227 WQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVVEGSVSVATPN 286 Query: 545 GKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPD 604 + L G+ FGE++++ +G R+A V + L L D P+ Sbjct: 287 PVE----LGPGAFFGEMALI------SGEPRSATVSAATTVSLLSLHSADFQMLCSSSPE 336 Query: 605 ----ARKLLLAK 612 RK L + Sbjct: 337 IAEIFRKTALER 348 >3I59-A nrPDB Length = 249 Score = 103 bits (256), Expect = 3e-22, Method: Composition-based stats. Identities = 32/133 (24%), Positives = 59/133 (44%), Gaps = 10/133 (7%) Query: 477 AEIAMQVHF-ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKR 535 + Q H E L + IFQ E +A L +LQ F G + +G+ G +YI+ Sbjct: 18 ENLYFQSHMDEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIIS 77 Query: 536 GRLQV--VDDDGKKVFV-TLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSK 592 G++++ DG++ + + +FGELSI + + VR+V + + Sbjct: 78 GKVKIGRRAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVS------MDR 131 Query: 593 TDLWNALREYPDA 605 L + + + P+ Sbjct: 132 DALRSWIADRPEI 144 >6BQ8-A nrPDB Length = 152 Score = 96.3 bits (238), Expect = 4e-20, Method: Composition-based stats. Identities = 27/133 (20%), Positives = 65/133 (48%), Gaps = 15/133 (11%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + LR V + ++ L +++ L+++ + GD+I ++G+ G +I+ +G+++V Sbjct: 11 YRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQS 70 Query: 544 ----DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRS---VGYTDLFVLSKTDLW 596 D ++ TLQ+G FGE +++ + + R+AN+ + V+ + Sbjct: 71 TEGHDQPQLIKTLQKGEYFGEKALI------SDDVRSANIIAEENDVAC--LVIDRETFN 122 Query: 597 NALREYPDARKLL 609 + + + +K L Sbjct: 123 QTVGTFEELQKYL 135 >4CYD-A nrPDB Length = 225 Score = 88.6 bits (218), Expect = 9e-18, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 45/101 (44%), Gaps = 3/101 (2%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV--DD 543 E L + IFQ + + L+ ++ F G I +G+ G +YI+ G++++ Sbjct: 4 EILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARHAP 63 Query: 544 DGKKVFV-TLQEGSVFGELSILNIAGSKNGNRRTANVRSVG 583 DG++ + + +FGELSI + + V + Sbjct: 64 DGRENLLTIMGPSDMFGELSIFDPGPRTSSAVCVTEVHAAT 104 >3SHR-A nrPDB Length = 299 Score = 88.2 bits (217), Expect = 1e-17, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 55/120 (45%), Gaps = 10/120 (8%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + E L+ V FQ +L++L L+ + G++I ++G G +I+ +G++ V + Sbjct: 155 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGKVNVTRE 214 Query: 544 DG----KKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 D TL +G FGE ++ + + RTANV + V+ + + + Sbjct: 215 DSPNEDPVFLRTLGKGDWFGEKAL------QGEDVRTANVIAAEAVTCLVIDRDSFKHLI 268 Score = 68.2 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 38/186 (20%), Positives = 79/186 (42%), Gaps = 18/186 (9%) Query: 461 SLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFI 520 S+ + ++ ++E + + E + ++ E + E+V + + I Sbjct: 14 SIEGRGSMQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCI 73 Query: 521 CKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVR 580 K+GD+G +Y+++ G+++V + K T+ G VFGEL+IL RTA V+ Sbjct: 74 IKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAILYN------CTRTATVK 125 Query: 581 SVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAEH 640 ++ L+ + + + L K E ++ ++ P Q EEI Sbjct: 126 TLVNVKLWAIDRQCFQTI------MMRTGLIKHTEYME----FLKSVPTFQSLPEEILSK 175 Query: 641 LNNAVK 646 L + ++ Sbjct: 176 LADVLE 181 >5JAX-A nrPDB Length = 135 Score = 87.5 bits (215), Expect = 2e-17, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 10/120 (8%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + E L+ V FQ +L++L L+ + G++I ++G G +I+ +G + V + Sbjct: 11 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 70 Query: 544 DGKKV----FVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 D TL +G FGE ++ + + RTANV + V+ + + + Sbjct: 71 DSPSEDPVFLRTLGKGDWFGEKAL------QGEDVRTANVIAAEAVTCLVIDRDSFKHLI 124 >4Z07-A nrPDB Length = 262 Score = 87.5 bits (215), Expect = 2e-17, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 10/120 (8%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + E L+ V FQ +L++L L+ + G++I ++G G +I+ +G + V + Sbjct: 138 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 197 Query: 544 DGKKV----FVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 D TL +G FGE ++ + + RTANV + V+ + + + Sbjct: 198 DSPSEDPVFLRTLGKGDWFGEKAL------QGEDVRTANVIAAEAVTCLVIDRDSFKHLI 251 Score = 67.8 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 35/154 (22%), Positives = 67/154 (43%), Gaps = 18/154 (11%) Query: 493 IFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTL 552 ++ E + E+V + + I K+GD+G +Y+++ G+++V + K T+ Sbjct: 29 FMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTM 86 Query: 553 QEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAK 612 G VFGEL+IL RTA V+++ L+ + + + L K Sbjct: 87 GPGKVFGELAILYN------CTRTATVKTLVNVKLWAIDRQCFQTI------MMRTGLIK 134 Query: 613 GREILKKDNLLDENAPEEQKTVEEIAEHLNNAVK 646 E ++ ++ P Q EEI L + ++ Sbjct: 135 HTEYME----FLKSVPTFQSLPEEILSKLADVLE 164 >4QX5-A nrPDB Length = 153 Score = 87.5 bits (215), Expect = 2e-17, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 10/120 (8%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + E L+ V FQ +L++L L+ + G++I ++G G +I+ +G + V + Sbjct: 11 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 70 Query: 544 DGKKV----FVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 D TL +G FGE ++ + + RTANV + V+ + + + Sbjct: 71 DSPSEDPVFLRTLGKGDWFGEKAL------QGEDVRTANVIAAEAVTCLVIDRDSFKHLI 124 >5FET-A nrPDB Length = 847 Score = 80.9 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 50/124 (40%), Gaps = 7/124 (5%) Query: 477 AEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRG 536 A I ++K+ IF+ L+ + + GD+I ++G++G YI+K G Sbjct: 396 ASIDHNNKKSIIKKMYIFRYLSEQQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNG 455 Query: 537 RLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLW 596 ++V + K TL + FGE ++L A + + + K+ Sbjct: 456 EVEVTKNG--KRLRTLGKNDYFGERALLYDEPRTASIISKA-----TSVECWFVDKSVFL 508 Query: 597 NALR 600 ++ Sbjct: 509 QIIQ 512 Score = 74.4 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 27/117 (23%), Positives = 45/117 (38%), Gaps = 3/117 (2%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + + V +F + +Q+F PG+ I K+GD G ++I+K G+ V + Sbjct: 161 NRSFIDSVSVFDMLTEAQKNMITNACVIQMFKPGETIVKQGDYGDVLFILKEGKATVFIN 220 Query: 544 DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTD-LFVLSKTDLWNAL 599 D K L +GS FGE ++L L + +L L Sbjct: 221 D--KEIRVLNKGSYFGERALLYDEPRSATIIAKEPTACASICRKLLNIVLGNLQVVL 275 Score = 68.6 bits (166), Expect = 1e-11, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 60/131 (45%), Gaps = 10/131 (7%) Query: 471 LPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREM 530 L +KL +I M +L+ + + L +Q VF GD + K+G+ G Sbjct: 32 LREKLSEDIEMI--KASLKNNLVCSTLNDNEILTLSNYMQFFVFKGGDLVIKQGEKGSYF 89 Query: 531 YIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVL 590 +I+ G+ V +D K ++ +GS FGE ++++ +R+A + + L+ + Sbjct: 90 FIINSGKFDVYVNDKK--VKSMGKGSSFGEAALIHNT------QRSATIMAETDGTLWGV 141 Query: 591 SKTDLWNALRE 601 ++ L++ Sbjct: 142 QRSTFRATLKQ 152 Score = 42.8 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 59/136 (43%), Gaps = 8/136 (5%) Query: 465 QQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKG 524 +++L ++ LQ + + E L++ IF+ A L +L ++ + I K Sbjct: 261 RKLLNIVLGNLQVVLFRNIMTEALQQSEIFRQFSAEQLNDLADTAIVRDYPANYHILHKD 320 Query: 525 DIGREMY-IVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVG 583 + Y IV G++++ DD L G FG+ +LN + V+S+ Sbjct: 321 KVKSVKYLIVLEGKVELFLDDES--IGILTRGKSFGDQYVLN-----QKQKFRHTVKSLD 373 Query: 584 YTDLFVLSKTDLWNAL 599 + +++++ L + L Sbjct: 374 VCKIALITESCLADCL 389 >5DYK-A nrPDB Length = 853 Score = 80.5 bits (197), Expect = 3e-15, Method: Composition-based stats. Identities = 31/140 (22%), Positives = 61/140 (43%), Gaps = 11/140 (7%) Query: 464 DQQVLKVL--PDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFIC 521 + L + + A I ++K+ IF+ L+ + + GD+I Sbjct: 387 TETCLADCLGNNNIDASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYII 446 Query: 522 KKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANV-R 580 ++G++G YI+K G +++V + KK TL + FGE ++L RTA+V Sbjct: 447 QEGEVGSRFYIIKNGEVEIVKN--KKRLRTLGKNDYFGERALLY------DEPRTASVIS 498 Query: 581 SVGYTDLFVLSKTDLWNALR 600 V + + + K+ ++ Sbjct: 499 KVNNVECWFVDKSVFLQIIQ 518 Score = 70.1 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 44/117 (37%), Gaps = 3/117 (2%) Query: 484 HFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD 543 + + V +F + +Q F G+ I K+GD G +YI+K G+ V + Sbjct: 167 NRTFIDSVSVFDMLTEAQKNMITNACVIQNFKSGETIVKQGDYGDVLYILKEGKATVYIN 226 Query: 544 DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTD-LFVLSKTDLWNAL 599 D + L++GS FGE ++L L + +L L Sbjct: 227 DEE--IRVLEKGSYFGERALLYDEPRSATIIAKEPTACASICRKLLNIVLGNLQVVL 281 Score = 68.2 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 29/132 (21%), Positives = 60/132 (45%), Gaps = 10/132 (7%) Query: 470 VLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGRE 529 L +KL +I M +L+ + + L +Q VF G+ + K+G+ G Sbjct: 37 ELREKLSEDIDMI--KTSLKNNLVCSTLNDNEILTLSNYMQFFVFKSGNLVIKQGEKGSY 94 Query: 530 MYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFV 589 +I+ G+ V +D K T+ +GS FGE ++++ +R+A + + L+ Sbjct: 95 FFIINSGKFDVYVNDKK--VKTMGKGSSFGEAALIHNT------QRSATIIAETDGTLWG 146 Query: 590 LSKTDLWNALRE 601 + ++ L++ Sbjct: 147 VQRSTFRATLKQ 158 Score = 42.8 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 42/294 (14%), Positives = 94/294 (31%), Gaps = 37/294 (12%) Query: 330 ISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPS-PVRNIE 388 + + G A ++ ++ + TL +F + L+ + + Sbjct: 115 MGKGSSFGEAALIHNTQRSATIIAETDGTLWGVQRSTFRATLKQLSNRNFNENRTFIDSV 174 Query: 389 YAFVTLDL----MCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQL 444 F L M + +++ + K Y+ Sbjct: 175 SVFDMLTEAQKNMITNACVIQNFKSGETIVKQGDYGDVLYILKEGKATVYI------NDE 228 Query: 445 EIRVIKWFDYLWTNKQSLSD------------------QQVLKVLPDKLQAEIAMQVHFE 486 EIRV++ Y + +++L ++ LQ + + E Sbjct: 229 EIRVLEKGSYFGERALLYDEPRSATIIAKEPTACASICRKLLNIVLGNLQVVLFRNIMTE 288 Query: 487 TLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVK-RGRLQVVDDDG 545 L++ IF+ L +L ++ + I K + YI+ G++++ DD Sbjct: 289 ALQQSEIFKQFSGDQLNDLADTAIVRDYPANYNILHKDKVKSVKYIIVLEGKVELFLDD- 347 Query: 546 KKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 L G FG+ +LN ++S+ + ++++T L + L Sbjct: 348 -TSIGILSRGMSFGDQYVLN-----QKQPFKHTIKSLEVCKIALITETCLADCL 395 >5KBF-A nrPDB Length = 301 Score = 79.0 bits (193), Expect = 7e-15, Method: Composition-based stats. Identities = 31/155 (20%), Positives = 66/155 (42%), Gaps = 12/155 (7%) Query: 485 FETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVD-- 542 E L + +F +V + G I +GD G +Y++ +G +++ Sbjct: 41 REALNESFLFNHLNKKEFEIIVNAFFDKNVEKGVNIINEGDYGDLLYVIDQGEVEIYKTK 100 Query: 543 -DDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALRE 601 ++ K+V L+ VFGEL++L + +R A ++ L+ L + +++ Sbjct: 101 ENNKKEVLTVLKSKDVFGELALLYNS------KRAATATALTKCHLWALDRESFTYIIKD 154 Query: 602 YPDARKLLLAKGREILKKDNLLDENAPEEQKTVEE 636 ++ + +IL N+L + P E+ V + Sbjct: 155 MVAKKRKMY---EDILSHVNILKDMDPYERCKVAD 186 Score = 79.0 bits (193), Expect = 7e-15, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 8/118 (6%) Query: 482 QVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV 541 +++ + L V I +D + ++ L+ + ++ G+ I K+G+ G +I+ G Sbjct: 161 KMYEDILSHVNILKDMDPYERCKVADCLKSKSYNDGEIIIKEGEEGDTFFILIDGNAVAS 220 Query: 542 DDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 D+ KV T +G FGEL++L R A +++ + + L + L Sbjct: 221 KDN--KVIKTYTKGDYFGELALLKNKP------RAATIKAQNFCQVVYLDRKSFKRLL 270 >6BYS-B nrPDB Length = 379 Score = 75.5 bits (184), Expect = 8e-14, Method: Composition-based stats. Identities = 37/173 (21%), Positives = 75/173 (43%), Gaps = 14/173 (8%) Query: 467 VLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDI 526 V KV+P + A+ + + K +F + +++ + F G+ + ++GD Sbjct: 112 VRKVIPKDYKTMAALA---KAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDE 168 Query: 527 GREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTD 586 G Y++ +G + V ++ ++ EG FGEL+++ G R A V++ Sbjct: 169 GDNFYVIDQGEMDVYVNNEWAT--SVGEGGSFGELALIY------GTPRAATVKAKTNVK 220 Query: 587 LFVLSKTDLWNALREYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAE 639 L+ + + L RK + + E L K ++L+ E+ TV + E Sbjct: 221 LWGIDRDSYRRIL-MGSTLRKRKMYE--EFLSKVSILESLDKWERLTVADALE 270 Score = 69.8 bits (169), Expect = 4e-12, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 49/144 (34%), Gaps = 12/144 (8%) Query: 460 QSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDF 519 + ++L + M + E L KV I + + + L+ F G Sbjct: 222 WGIDRDSYRRILMGSTLRKRKM--YEEFLSKVSILESLDKWERLTVADALEPVQFEDGQK 279 Query: 520 ICKKGDIGREMYIVKRGRLQVVD----DDGKKVFVTLQEGSVFGELSILNIAGSKNGNRR 575 I +G+ G E +I+ G V+ ++ L FGE+++L R Sbjct: 280 IVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRP------R 333 Query: 576 TANVRSVGYTDLFVLSKTDLWNAL 599 A V + G L + L Sbjct: 334 AATVVARGPLKCVKLDRPRFERVL 357 >2QCS-B nrPDB Length = 291 Score = 75.5 bits (184), Expect = 8e-14, Method: Composition-based stats. Identities = 37/173 (21%), Positives = 75/173 (43%), Gaps = 14/173 (8%) Query: 467 VLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDI 526 V KV+P + A+ + + K +F + +++ + F G+ + ++GD Sbjct: 23 VRKVIPKDYKTMAALA---KAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDE 79 Query: 527 GREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTD 586 G Y++ +G + V ++ ++ EG FGEL+++ G R A V++ Sbjct: 80 GDNFYVIDQGEMDVYVNNEWAT--SVGEGGSFGELALIY------GTPRAATVKAKTNVK 131 Query: 587 LFVLSKTDLWNALREYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAE 639 L+ + + L RK + + E L K ++L+ E+ TV + E Sbjct: 132 LWGIDRDSYRRIL-MGSTLRKRKMYE--EFLSKVSILESLDKWERLTVADALE 181 Score = 68.2 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 48/144 (33%), Gaps = 12/144 (8%) Query: 460 QSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDF 519 + ++L + M + E L KV I + + + L+ F G Sbjct: 133 WGIDRDSYRRILMGSTLRKRKM--YEEFLSKVSILESLDKWERLTVADALEPVQFEDGQK 190 Query: 520 ICKKGDIGREMYIVKRGRLQVVD----DDGKKVFVTLQEGSVFGELSILNIAGSKNGNRR 575 I +G+ G E +I+ G V+ ++ L FGE+++L Sbjct: 191 IVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPK------ 244 Query: 576 TANVRSVGYTDLFVLSKTDLWNAL 599 A V + G L + L Sbjct: 245 AATVVARGPLKCVKLDRPRFERVL 268 >4EV0-A nrPDB Length = 216 Score = 73.2 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 55/119 (46%), Gaps = 9/119 (7%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD---D 544 ++ +F + + Q +++ G I +GD+G+ +Y+V G++++ Sbjct: 1 MKGSPLFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGG 60 Query: 545 GKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYP 603 ++ L G +FGE+S+L+ R+A+ +V T+L L + D +R P Sbjct: 61 QERTLALLGPGELFGEMSLLDEG------ERSASAVAVEDTELLALFREDYLALIRRLP 113 >4DIN-B nrPDB Length = 381 Score = 71.7 bits (174), Expect = 1e-12, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 50/144 (34%), Gaps = 12/144 (8%) Query: 460 QSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDF 519 + ++L + M + E L KV I + E + L+ F G+ Sbjct: 224 WGIDRDSYRRILMGSTLRKRKM--YEEFLSKVSILESLEKWERLTVADALEPVQFEDGEK 281 Query: 520 ICKKGDIGREMYIVKRGRLQVVD----DDGKKVFVTLQEGSVFGELSILNIAGSKNGNRR 575 I +G+ G + YI+ G V+ ++ L FGE+++L R Sbjct: 282 IVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRP------R 335 Query: 576 TANVRSVGYTDLFVLSKTDLWNAL 599 A V + G L + L Sbjct: 336 AATVVARGPLKCVKLDRPRFERVL 359 Score = 69.8 bits (169), Expect = 4e-12, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 73/173 (42%), Gaps = 14/173 (8%) Query: 467 VLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDI 526 V KV+P + A+ + + K +F + +++ + G+ + ++G+ Sbjct: 114 VRKVIPKDYKTMTALA---KAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNE 170 Query: 527 GREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTD 586 G Y+V +G + V + + + EG FGEL+++ G R A V++ Sbjct: 171 GDNFYVVDQGEVDVYVNG--EWVTNISEGGSFGELALIY------GTPRAATVKAKTDLK 222 Query: 587 LFVLSKTDLWNALREYPDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAE 639 L+ + + L RK + + E L K ++L+ E+ TV + E Sbjct: 223 LWGIDRDSYRRIL-MGSTLRKRKMYE--EFLSKVSILESLEKWERLTVADALE 272 >4ORF-A nrPDB Length = 340 Score = 69.0 bits (167), Expect = 7e-12, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 54/130 (41%), Gaps = 9/130 (6%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV--DDDG 545 L + F C L L +L+ PG + ++GD +++ GR+QV DG Sbjct: 19 LAALEFFTGCRPSALEPLATQLRPLKAEPGQVLIRQGDPALTFMLIESGRVQVSHAVADG 78 Query: 546 KKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDA 605 + + ++ G + GE+++L A TA V + +V + L Sbjct: 79 PPIVLDIEPGLIIGEIALLRDAPK------TATVVAAEPVIGWVGDRDAFDTILHLPGMF 132 Query: 606 RKLL-LAKGR 614 +L+ +A+ R Sbjct: 133 DRLVRIARQR 142 >6FTF-B nrPDB Length = 304 Score = 65.5 bits (158), Expect = 8e-11, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 49/121 (40%), Gaps = 9/121 (7%) Query: 482 QVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV 541 + + + L V ++ +L L + FSPG++I G+ G +YI+ G ++V+ Sbjct: 154 ETYIQFLANVPFLGGLDSYEKLQLADALSSEEFSPGEYIIHYGEEGEWLYIIMEGTVEVI 213 Query: 542 ---DDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNA 598 D +G GEL L N +R A+V + + L++ Sbjct: 214 GRDADGEPTKVCEFTQGDHIGELEFL------NNHRTVADVVATTHVITAKLNRRHFEMC 267 Query: 599 L 599 L Sbjct: 268 L 268 Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 54/146 (36%), Gaps = 13/146 (8%) Query: 458 NKQSLS-DQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSP 516 + + ++ L P ++E M + + L +F + + +Q F Sbjct: 9 RSEGIDPEKAKLYQAPYFEKSEDEMNLITKLLTHNVLFSFLNTKDIKVVAGAMQRATFKH 68 Query: 517 GDFICKKGDIG-REMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRR 575 D I + G ++YI++ G ++ + K T EG+ GEL ++ + Sbjct: 69 DDCIMEAGQTTCNKLYIIQSGHADIIKEGQKVYLKT--EGTAVGELELMYDTPVVATVKV 126 Query: 576 TANVRSVGYTDL--FVLSKTDLWNAL 599 + +L +VL + N + Sbjct: 127 CTD-------ELIAWVLDRDTYRNLV 145 >4I0B-A nrPDB Length = 222 Score = 65.5 bits (158), Expect = 8e-11, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 42/103 (40%), Gaps = 8/103 (7%) Query: 513 VFSPGDFICKKGDIGREMYIVKRGRLQVVDDDG---KKVFVTLQEGSVFGELSILNIAGS 569 + + +G+ +Y + +G + V+ D + + L +G GEL + Sbjct: 35 KYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLF----- 89 Query: 570 KNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAK 612 + G R+A VR+ ++ +S ++ PD L A+ Sbjct: 90 EEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQ 132 >3KCC-A nrPDB Length = 260 Score = 65.5 bits (158), Expect = 8e-11, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 42/103 (40%), Gaps = 8/103 (7%) Query: 513 VFSPGDFICKKGDIGREMYIVKRGRLQVVDDDG---KKVFVTLQEGSVFGELSILNIAGS 569 + + +G+ +Y + +G + V+ D + + L +G GEL + Sbjct: 73 KYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLF----- 127 Query: 570 KNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAK 612 + G R+A VR+ ++ +S ++ PD L A+ Sbjct: 128 EEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQ 170 >3J4Q-B nrPDB Length = 402 Score = 62.1 bits (149), Expect = 1e-09, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 42/105 (40%), Gaps = 10/105 (9%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD---- 543 + V +F+ E ++V + +++ G+ I +G+ YI++ G + ++ Sbjct: 254 IESVPLFKSLEMSERMKIVDVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTK 313 Query: 544 ------DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSV 582 + + +G FGEL+++ +V+ + Sbjct: 314 SNKNGGNQEVEIAHCHKGQYFGELALVTNKPRAASAYAVGDVKCL 358 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 49/116 (42%), Gaps = 8/116 (6%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV--DD 543 E + + +F++ + L++++ + ++ + + +GD G Y+++RG ++ D Sbjct: 130 EACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKD 189 Query: 544 DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 + + FGEL+++ R A + + L+ L + + Sbjct: 190 NQTRSVGQYDNRGSFGELALMYNTP------RAATIIATSEGSLWGLDRVTFRRII 239 >3E97-A nrPDB Length = 231 Score = 61.7 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 50/119 (42%), Gaps = 9/119 (7%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKK 547 L++ +FQ+ + E + + + F P + + ++ G +++V G ++V Sbjct: 8 LKRSPLFQNVPEDAMREALKVVTERNFQPDELVVEQDAEGEALHLVTTGVVRVSRVSLGG 67 Query: 548 VFVTLQE---GSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYP 603 L + V GE ++L R+A+VR++ +L + LR +P Sbjct: 68 RERVLGDIYAPGVVGETAVLAH------QERSASVRALTPVRTLMLHREHFELILRRHP 120 >2QVS-B nrPDB Length = 310 Score = 61.7 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 42/105 (40%), Gaps = 10/105 (9%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD---- 543 + V +F+ E ++V + +++ G+ I +G+ YI++ G + ++ Sbjct: 162 IESVPLFKSLEMSERMKIVDVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTK 221 Query: 544 ------DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSV 582 + + +G FGEL+++ +V+ + Sbjct: 222 SNKNGGNQEVEIAHCHKGQYFGELALVTNKPRAASAYGVGDVKCL 266 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 49/116 (42%), Gaps = 8/116 (6%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV--DD 543 E + + +F++ + L++++ + ++ + + +GD G Y+++RG ++ D Sbjct: 38 EACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKD 97 Query: 544 DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 + + FGEL+++ R A + + L+ L + + Sbjct: 98 NQTRSVGQYDNRGSFGELALMYNTP------RAATIIATSEGSLWGLDRVTFRRII 147 >4F7Z-A nrPDB Length = 999 Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 39/154 (25%), Positives = 63/154 (40%), Gaps = 17/154 (11%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDD--- 544 L+ V+ F+ LL ++ L + G + ++GDIG Y V G L V + Sbjct: 44 LKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 103 Query: 545 --GKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREY 602 TL G+ FGE SIL+ R A + + ++L + + D +Y Sbjct: 104 HQDAVTICTLGIGTAFGE-SILDNTP------RHATIVTRESSELLRIEQEDFKALWEKY 156 Query: 603 PDARKLLLAKGREILK----KDNLLD-ENAPEEQ 631 LLA +++ D + D EN P E+ Sbjct: 157 RQYMAGLLAPPYGVMETGSNNDRIPDKENVPSEK 190 Score = 54.0 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 481 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQ-VFSPGDFICKKGDIGREMYIVKRGRLQ 539 +++ ++ L ++ + EL L + G + +G+ G YI+ +G + Sbjct: 332 LEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVN 391 Query: 540 VVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 VV GK V TL EG FG+L+++N A V + K D L Sbjct: 392 VVIY-GKGVVCTLHEGDDFGKLALVNDAPRAASI-----VLREDNCHFLRVDKEDGNRIL 445 Query: 600 R 600 R Sbjct: 446 R 446 >1O7F-A nrPDB Length = 469 Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 39/154 (25%), Positives = 63/154 (40%), Gaps = 17/154 (11%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDD--- 544 L+ V+ F+ LL ++ L + G + ++GDIG Y V G L V + Sbjct: 44 LKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 103 Query: 545 --GKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREY 602 TL G+ FGE SIL+ R A + + ++L + + D +Y Sbjct: 104 HQDAVTICTLGIGTAFGE-SILDNTP------RHATIVTRESSELLRIEQEDFKALWEKY 156 Query: 603 PDARKLLLAKGREILK----KDNLLD-ENAPEEQ 631 LLA +++ D + D EN P E+ Sbjct: 157 RQYMAGLLAPPYGVMETGSNNDRIPDKENVPSEK 190 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 481 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQ-VFSPGDFICKKGDIGREMYIVKRGRLQ 539 +++ ++ L ++ + EL L + G + +G+ G YI+ +G + Sbjct: 332 LEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVN 391 Query: 540 VVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 VV GK V TL EG FG+L+++N A V + K D L Sbjct: 392 VVIY-GKGVVCTLHEGDDFGKLALVNDAPRAASI-----VLREDNCHFLRVDKEDFNRIL 445 Query: 600 R 600 R Sbjct: 446 R 446 >2OZ6-A nrPDB Length = 207 Score = 60.1 bits (144), Expect = 4e-09, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 51/121 (42%), Gaps = 5/121 (4%) Query: 502 LAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQ---EGSVF 558 L +L+ + ++ I GD ++ + +G + ++ +D + + G F Sbjct: 6 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 65 Query: 559 GELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILK 618 GEL + GS+ R+A VR+ ++ +S ++ + L ++ + L+ Sbjct: 66 GELGLFEKEGSEQ--ERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLR 123 Query: 619 K 619 K Sbjct: 124 K 124 >3IWZ-A nrPDB Length = 230 Score = 59.0 bits (141), Expect = 7e-09, Method: Composition-based stats. Identities = 37/198 (18%), Positives = 76/198 (38%), Gaps = 30/198 (15%) Query: 497 CEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV---DDDGKKVFVTLQ 553 +AG + + + + + + GD +Y V G + ++ DDD + V Sbjct: 22 LDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYFG 81 Query: 554 EGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALR--EYPDARKLLLA 611 G GE+ + + R +R+ +L +S L + PDA ++L A Sbjct: 82 SGEFVGEMGLFI-----ESDTREVILRTRTQCELAEISYERLQQLFQTSLSPDAPRILYA 136 Query: 612 KGREILKKDNLLDENAPEEQ------------------KTVEEIAEHLNNAVKVLQTRMA 653 G ++ K+ LLD + K E ++ ++V + +A Sbjct: 137 IGVQLSKR--LLDTTRKASRLAFLDVTDRIVRTLHDLSKEPEAMSHPQGTQLRVSRQELA 194 Query: 654 RLIVEHSSTEGKLMKRIE 671 RL+ G+++K+++ Sbjct: 195 RLVGCSREMAGRVLKKLQ 212 >4MGY-E nrPDB Length = 694 Score = 57.8 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 481 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQ-VFSPGDFICKKGDIGREMYIVKRGRLQ 539 +++ ++ L ++ + EL L + G + +G+ G YI+ +G + Sbjct: 27 LEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVN 86 Query: 540 VVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 VV GK V TL EG FG+L+++N A V + K D L Sbjct: 87 VVIY-GKGVVCTLHEGDDFGQLALVNDAPRAASI-----VLREDNCHFLRVDKEDFNRIL 140 Query: 600 R 600 R Sbjct: 141 R 141 >1CX4-A nrPDB Length = 305 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 47/116 (40%), Gaps = 8/116 (6%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVD--D 543 E + + +F++ + +++++ + ++ G+ + +GD G Y++ RG + D Sbjct: 34 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 93 Query: 544 DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 + FGEL+++ R A + + L+ L + + Sbjct: 94 GVGRCVGNYDNRGSFGELALMYNTP------RAATITATSPGALWGLDRVTFRRII 143 Score = 57.0 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 17/111 (15%), Positives = 45/111 (40%), Gaps = 9/111 (8%) Query: 482 QVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV- 540 +++ + + + E ++V + +V++ G+ I +GD +IV+ G +++ Sbjct: 152 KMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVRIT 211 Query: 541 --------VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVG 583 ++++G G FGEL+++ V+ + Sbjct: 212 MKRKGKSDIEENGAVEIARCLRGQYFGELALVTNKPRAASAHAIGTVKCLA 262 >4X6Q-B nrPDB Length = 416 Score = 57.0 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 46/111 (41%), Gaps = 9/111 (8%) Query: 482 QVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV- 540 +++ + + + E ++V + +V++ G+ I +GD+ +IV+ G +++ Sbjct: 263 KMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKIT 322 Query: 541 --------VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVG 583 V+++G G FGEL+++ V+ + Sbjct: 323 MKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLA 373 Score = 55.9 bits (133), Expect = 7e-08, Method: Composition-based stats. Identities = 17/116 (14%), Positives = 46/116 (39%), Gaps = 8/116 (6%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVD--D 543 E + + +F++ + +++++ + ++ G+ + +GD G Y++ RG + D Sbjct: 145 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 204 Query: 544 DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 + FGEL+++ A + + L+ L + + Sbjct: 205 GVGRCVGNYDNRGSFGELALMYNTPK------AATITATSPGALWGLDRVTFRRII 254 >4AVC-A nrPDB Length = 333 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 9/132 (6%) Query: 488 LRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV--VDDDG 545 L + +FQ C A L L +Q + G + ++G+ ++ G +V V DDG Sbjct: 15 LAGMDVFQGCPAEGLVSLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEVSHVGDDG 74 Query: 546 KKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDA 605 + G + GE+++L + R+A V ++ + + + P Sbjct: 75 VAIIARALPGMIVGEIALLRDSP------RSATVTTIEPLTGWTGGRGAFATMVHI-PGV 127 Query: 606 RKLLLAKGREIL 617 + LL R+ L Sbjct: 128 GERLLRTARQRL 139 >3DKW-A nrPDB Length = 227 Score = 53.6 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 46/121 (38%), Gaps = 8/121 (6%) Query: 483 VHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV-- 540 VH + L+ +F+ L EL+ L G ++ ++G+ Y + G +++ Sbjct: 6 VHQQLLQSHHLFEPLSPVQLQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIYR 65 Query: 541 -VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNAL 599 + +K+ E + F E + + A ++V + LF S L Sbjct: 66 LTPEGQEKILEVTNERNTFAEAMMFMDTPNY-----VATAQAVVPSQLFRFSNKAYLRQL 120 Query: 600 R 600 + Sbjct: 121 Q 121 >5W5B-A nrPDB Length = 236 Score = 52.8 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 31/182 (17%), Positives = 71/182 (39%), Gaps = 14/182 (7%) Query: 497 CEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQ--VVDDDGKKVFVTLQE 554 ++ L LQ++ F+PG + ++IV+ G ++ V + V L Sbjct: 37 LHRDDVSALAETLQVKEFAPGAVVFHADQTADGVWIVRHGLIELAVGSRRRRAVVNILHP 96 Query: 555 GSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPD-ARKLLLAKG 613 G V G++ +L R++ L + L +P AR+ L + Sbjct: 97 GDVDGDIPLLLEMPMVYTG------RALTQATCLFLDRQAFERLLATHPAIARRWLSSVA 150 Query: 614 REI----LKKDNLLDENAPEEQKTVEEIAEHLNNAVKVLQTRMARLIVEHSSTEGKLMKR 669 + + ++ +L P + + + E ++ +++ Q +A ++ + K++K Sbjct: 151 QRVSTAQIRLMGMLGRPLPAQVAQL-LLDEAIDARIELAQRTLAAMLGAQRPSINKILKE 209 Query: 670 IE 671 E Sbjct: 210 FE 211 >2XKO-A nrPDB Length = 222 Score = 52.0 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 30/121 (24%), Positives = 54/121 (44%), Gaps = 12/121 (9%) Query: 493 IFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQ---VVDDDGKKVF 549 +F++ +G L LQ++ F G I GD +Y++ +G ++ V + + Sbjct: 11 MFRELGSGKL-----PLQIEQFERGKTIFFPGDPAERVYLLVKGAVKLSRVYESGEEITV 65 Query: 550 VTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLL 609 L+E SVFG LS+L + R + + LF + + AL E P+ ++ Sbjct: 66 ALLRENSVFGVLSLLT----GQRSDRFYHAVAFTPVQLFSVPIEFMQKALIERPELANVM 121 Query: 610 L 610 L Sbjct: 122 L 122 >3LA7-A nrPDB Length = 243 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 25/103 (24%), Positives = 44/103 (42%), Gaps = 7/103 (6%) Query: 511 LQVFSPGDFICKKGDIGREMYIVKRGRLQ---VVDDDGKKVFVTLQEGSVFGELSILNIA 567 ++ F I GD +Y + +G ++ V + + L+E SVFG LS+L Sbjct: 45 VETFERNKTIFFPGDPAERVYFLLKGAVKLSRVYEAGEEITVALLRENSVFGVLSLLT-- 102 Query: 568 GSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLL 610 N + R + + +L + AL+E P+ L+L Sbjct: 103 --GNKSDRFYHAVAFTPVELLSAPIEQVEQALKENPELSMLML 143 >1ZYB-A nrPDB Length = 232 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 55/130 (42%), Gaps = 8/130 (6%) Query: 481 MQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFS--PGDFICKKGDIGREMYIVKRGRL 538 M+ F+TL ++ +FQ ++ K++L G+ I K G+ ++ + +G + Sbjct: 13 METMFDTLLQLPLFQGLCHEDFTSILDKVKLHFIKHKAGETIIKSGNPCTQLCFLLKGEI 72 Query: 539 QVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFV--LSKTDLW 596 +V + + ++ +++ E L S G V +T++ +SK + Sbjct: 73 SIVTNAKENIYTVIEQI----EAPYLIEPQSLFGMNTNYASSYVAHTEVHTVCISKAFVL 128 Query: 597 NALREYPDAR 606 + L Y R Sbjct: 129 SDLFRYDIFR 138 >2A79-B nrPDB Length = 499 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 45/309 (14%), Positives = 98/309 (31%), Gaps = 52/309 (16%) Query: 185 TYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAY 244 TYS +G+ + F + + L + + + + G + Sbjct: 204 TYSN-STIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAG------------F 250 Query: 245 WQSKQYRIDGISLIPLDYILGWPIP--------YINWRGLPILRLNRLIRYKRVRNCLER 296 + + ID +++IP LG + L ILR+ RL+R R+ Sbjct: 251 FTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRH 310 Query: 297 T----ETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLP 352 + ++ + R + ++ + + I + F + + Sbjct: 311 SKGLQILGQTLKASMRELGLLIFFLFI----GVILFSSAVYFAEA--------------- 351 Query: 353 DDITDTLLRRYVYSFYWSTLILTTIGEVP-SPVRNIEYAFVTLDLMCGVLIFATIVGNVG 411 D D+ +F+W+ + +TT+G P +L + GVL A V + Sbjct: 352 -DERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIV 410 Query: 412 SMISNMSAART--EFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLK 469 S + T E Q + + ++ + R + + Q+ + Sbjct: 411 SNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRS----ASTISKSDYMEIQEGVN 466 Query: 470 VLPDKLQAE 478 + + E Sbjct: 467 NSNEDFREE 475 >4JTA-B nrPDB Length = 514 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 42/311 (13%), Positives = 96/311 (30%), Gaps = 60/311 (19%) Query: 185 TYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAY 244 TYSQ +G+ + F + + L + + + + G + Sbjct: 223 TYSQ-STIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAG------------F 269 Query: 245 WQSKQYRIDGISLIPLDYILGWPIPYINW-------RGLPILRLNRLIRYKRVRN----- 292 + + ID +++IP + + R + I R+ R++R ++ Sbjct: 270 FTNIMNIIDIVAIIPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRIFKLSRHSKGL 329 Query: 293 --CLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQS 350 + + + + I+ + +YF ++ S Sbjct: 330 QILGQTLKASMRELGLLIFFLFIGVILFS----SAVYFAEADERD----------SQFPS 375 Query: 351 LPDDITDTLLRRYVYSFYWSTLILTTIGEVP-SPVRNIEYAFVTLDLMCGVLIFATIVGN 409 +PD +F+W+ + +TT+G P +L + GVL A V Sbjct: 376 IPD------------AFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPV 423 Query: 410 VGSMISNMSAART--EFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQV 467 + S + T E Q + + ++ + R + + Q+ Sbjct: 424 IVSNFNYFYHRETEGEEQAQYLQVTSSPKIPSSPDLKKSRS----ASTISKSDYMEIQEG 479 Query: 468 LKVLPDKLQAE 478 + + + E Sbjct: 480 VNNSNEDFREE 490 >1ORQ-C nrPDB Length = 223 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 11/65 (16%), Positives = 26/65 (40%), Gaps = 2/65 (3%) Query: 354 DITDTLLRRYVYSFYWSTLILTTIGEVPS-PVRNIEYAFVTLDLMCGVLIFATIVGNVGS 412 D ++ + + +W+ + TT+G P I ++ G+ ++G V + Sbjct: 158 DPNSSIKSVF-DALWWAVVTATTVGYGDVVPATPIGKVIGIAVMLTGISALTLLIGTVSN 216 Query: 413 MISNM 417 M + Sbjct: 217 MFQKI 221 >2A9H-A nrPDB Length = 155 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 33/95 (34%), Gaps = 6/95 (6%) Query: 319 IIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIG 378 +HW A + I L +++ + + L Y + +WS TT+G Sbjct: 46 ALHWRAAGAATVLLVIVLLAGSYLAVLAERGAP-----GAALISYPDALWWSVETATTVG 100 Query: 379 EVP-SPVRNIEYAFVTLDLMCGVLIFATIVGNVGS 412 PV + ++ G+ + + V + Sbjct: 101 YGDLYPVTLWGRCVAVVVMVAGITSYGLVFAAVAT 135 >2D93-A nrPDB Length = 134 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 21/116 (18%), Positives = 42/116 (36%), Gaps = 8/116 (6%) Query: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVF-SPGDFICKKGDIGREMYIVKRGRLQVVDDD 544 E + ++ F + + EL + +V G I + G Y++ G +++ D Sbjct: 16 EFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVILNGTVEISHPD 75 Query: 545 GKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALR 600 GK + + G+ FG L+ R + +++ D W L Sbjct: 76 GKVENLFM--GNSFGITPTLDKQYMHGIVRTKVD-----DCQFVCIAQQDYWRILN 124 >3B02-A nrPDB Length = 195 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 36/89 (40%), Gaps = 9/89 (10%) Query: 514 FSPGDFICKKGDIGREMYIVKRG---RLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSK 570 F+ + I +G+ R +Y ++ G ++++ D + G FGE ++ A Sbjct: 4 FARKETIYLRGEEARTLYRLEEGLVRVVELLPDGRLITLRHVLPGDYFGEEALEGKAYRY 63 Query: 571 NGNRRTANV------RSVGYTDLFVLSKT 593 T V R++ + L +++ Sbjct: 64 TAEAMTEAVVQGLEPRAMDHEALHRVARN 92 >4XDL-A nrPDB Length = 282 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 36/79 (45%), Gaps = 7/79 (8%) Query: 365 YSFYWSTLILTTIGE-VPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTE 423 +F+++ ++TTIG +P F L + G+ +F ++ +G + + Sbjct: 96 SAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTI------ 149 Query: 424 FQNKMDGIKQYMELRKVSK 442 F + +++ ++VS+ Sbjct: 150 FGKSIARVEKVFRKKQVSQ 168 >4H33-A nrPDB Length = 137 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 13/89 (14%), Positives = 31/89 (34%), Gaps = 2/89 (2%) Query: 349 QSLPDDITDTLLRRYVYSFYWSTLILTTIGEVP-SPVRNIEYAFVTLDLMCGVLIFATIV 407 +P + + Y + +W+ + TT+G PV I ++ ++ G+ I Sbjct: 30 IPVPMVFIEPEINNYPDALWWAIVTATTVGYGDIVPVTPIGRILASIMMLFGIAFIGMIT 89 Query: 408 GNVGSMISNMSAARTEFQNKMDGIKQYME 436 + + + + I Q + Sbjct: 90 STITNFF-RCKKPTNSSTQRANKITQLIS 117 >3RBZ-A nrPDB Length = 340 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 29/75 (38%), Gaps = 10/75 (13%) Query: 360 LRRYVYSFYWSTLILTTIGEVP-SPVRNIEYAFVTLDLMCGVLIFATIVGNVGS------ 412 + S YW+ + + T+G SP + F ++ G+ FA V + + Sbjct: 43 GESWTVSLYWTFVTIATVGYGDYSPSTPLGMYFTVTLIVLGIATFAVAVARLLTFLINRE 102 Query: 413 ---MISNMSAARTEF 424 +I + A++ Sbjct: 103 QMKLIGLIDVAKSRH 117 >3EFF-K nrPDB Length = 139 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 19/130 (14%), Positives = 40/130 (30%), Gaps = 6/130 (4%) Query: 319 IIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIG 378 +HW A + I L +++ + + L Y + +WS TT+G Sbjct: 2 ALHWRAAGAATVLLVIVLLAGSYLAVLAERGAP-----GAQLITYPRALWWSVETATTVG 56 Query: 379 EVP-SPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMEL 437 PV + ++ G+ F + + + R + Sbjct: 57 YGDLYPVTLWGRLVAVVVMVAGITSFGLVTAALATWFVGREQERRGHFVRHSEKAAEEAY 116 Query: 438 RKVSKQLEIR 447 + ++ L R Sbjct: 117 TRTTRALHER 126 >1F6G-A nrPDB Length = 160 Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 19/130 (14%), Positives = 40/130 (30%), Gaps = 6/130 (4%) Query: 319 IIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIG 378 +HW A + I L +++ + + L Y + +WS TT+G Sbjct: 23 ALHWAAAGAATVLLVIVLLAGSYLAVLAERGAP-----GAQLITYPAALWWSVETATTVG 77 Query: 379 EVP-SPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMEL 437 PV + ++ G+ F + + + R + Sbjct: 78 YGDLYPVTLWGRCVAVVVMVAGITSFGLVTAALATWFVGREQERRGHFVRHSEKAAEEAY 137 Query: 438 RKVSKQLEIR 447 + ++ L R Sbjct: 138 TRTTRALHER 147 >3SWF-A nrPDB Length = 74 Score = 38.9 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 17/44 (38%), Positives = 29/44 (65%) Query: 634 VEEIAEHLNNAVKVLQTRMARLIVEHSSTEGKLMKRIEMLEKHL 677 +EE + ++V +LQTR AR++ E+ S + KL +R+ +EK L Sbjct: 5 LEEKVTRMESSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFL 48 >2Q6A-A nrPDB Length = 114 Score = 38.6 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 362 RYVYSFYWSTLILTTIG-EVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMIS 415 R + + Y+S + LTT+G SP + F L + G+ + + + + Sbjct: 49 RPIDALYFSVVTLTTVGEGNFSPQTDFGKIFTILYIFIGIGLVFGFIHKLAVNVQ 103 >3VOU-A nrPDB Length = 148 Score = 38.6 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 34/88 (38%), Gaps = 11/88 (12%) Query: 362 RYVYSFYWSTLILTTIG-EVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMIS----- 415 R + + Y+S + LTT+G SP + F L + G+ + + + + Sbjct: 52 RPLDALYFSVVTLTTVGDGNFSPQTDFGKVFTILYIFIGIGLVFGFIHKLAVNVQLPSIL 111 Query: 416 -----NMSAARTEFQNKMDGIKQYMELR 438 A R E K++ I++ + Sbjct: 112 SNRKKETDAYRLEVMEKLEAIEKKLAEH 139 >3PJS-K nrPDB Length = 166 Score = 37.0 bits (84), Expect = 0.026, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 28/93 (30%), Gaps = 1/93 (1%) Query: 321 HWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEV 380 H +A + L + G L Y + +WS TT+G Sbjct: 26 HGSALQWRAAGAATVLLVIVLLAGSYLAVLAERGAPGAQLITYPRALWWSVETATTVGYG 85 Query: 381 P-SPVRNIEYAFVTLDLMCGVLIFATIVGNVGS 412 PV + ++ G+ F + + + Sbjct: 86 DLYPVTLWGRLVAVVVMVAGITSFGLVTAALAT 118 >2GAU-A nrPDB Length = 232 Score = 36.6 bits (83), Expect = 0.039, Method: Composition-based stats. Identities = 9/80 (11%), Positives = 28/80 (35%), Gaps = 3/80 (3%) Query: 507 LKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDD---DGKKVFVTLQEGSVFGELSI 563 ++Q + +GDI ++ + G+++++ + + ++ G FG Sbjct: 31 KEIQPFPCKKASTVFSEGDIPNNLFYLYEGKIKILREGVYGRFHISRIVKPGQFFGMRPY 90 Query: 564 LNIAGSKNGNRRTANVRSVG 583 + N + + Sbjct: 91 FAEETCSSTAIAVENSKVLA 110 >6CQ6-A nrPDB Length = 312 Score = 36.2 bits (82), Expect = 0.057, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Query: 365 YSFYWSTLILTTIG-EVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMS 418 SF+++ ++TTIG SP F + + G+ +F ++ VG + + Sbjct: 112 SSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 166 >4TWK-A nrPDB Length = 283 Score = 36.2 bits (82), Expect = 0.057, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Query: 365 YSFYWSTLILTTIG-EVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMS 418 SF+++ ++TTIG SP F + + G+ +F ++ VG + + Sbjct: 107 SSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 161 >5VMS-A nrPDB Length = 548 Score = 35.5 bits (80), Expect = 0.080, Method: Composition-based stats. Identities = 43/266 (16%), Positives = 86/266 (32%), Gaps = 60/266 (22%) Query: 179 NMKEMPTYSQYPDLGWSKY-WHFRMLWVFF---------------DLLMDCVYLIDTFLN 222 N E PT GW + +HF + + +L + ++ ++ L Sbjct: 37 NFLERPT-------GWKCFVYHFTVFLIVLICLIFSVLSTIQQYNNLATETLFWMEIVL- 88 Query: 223 YRMGYMDQGLVVREAEKVTKAYWQSKQ----------YRIDGISLIPLDYI-----LGWP 267 + + VVR ++ + ID I ++ + G Sbjct: 89 --VVFFGAEYVVRLWSAGCRSKYVGVWGRLRFARKPISVIDLIVVVASVIVLCVGSNGQV 146 Query: 268 IPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLY 327 RG+ L++ R++ R +R++ V +I H + Sbjct: 147 FATSAIRGIRFLQILRMLHVDR-------------QGGTWRLLGSVVFI----HRQELIT 189 Query: 328 FWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPS-PVRN 386 ++GL ++ K ++ D + Y + +W + +TTIG P Sbjct: 190 TLYIGFLGLIFSSYFVYLAEKDAI-DSSGEYQFGSYADALWWGVVTVTTIGYGDKVPQTW 248 Query: 387 IEYAFVTLDLMCGVLIFATIVGNVGS 412 I + + + FA G +GS Sbjct: 249 IGKTIASCFSVFAISFFALPAGILGS 274 >3UM7-A nrPDB Length = 309 Score = 35.5 bits (80), Expect = 0.093, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 35/83 (42%), Gaps = 7/83 (8%) Query: 365 YSFYWSTLILTTIGE-VPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTE 423 +F++S I+TTIG + + F + G+ +F ++ VG + ++ Sbjct: 118 SAFFFSGTIITTIGYGNVALRTDAGRLFCIFYALVGIPLFGILLAGVG---DRLGSSLRH 174 Query: 424 FQNKMDGIKQYMELRKVSKQLEI 446 ++ I +++ V +L Sbjct: 175 GIGHIEAI--FLKWH-VPPELVR 194 >3FB6-C nrPDB Length = 104 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 32/95 (33%), Gaps = 6/95 (6%) Query: 319 IIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIG 378 + W A + I L +++ + + L Y + +WS TT+G Sbjct: 3 ALQWRAAGAATVLLVIVLLAGSYLAVLAERGAP-----GAQLITYPRALWWSVETATTVG 57 Query: 379 EVP-SPVRNIEYAFVTLDLMCGVLIFATIVGNVGS 412 PV + ++ G+ F + + + Sbjct: 58 YGDLYPVTLWGRCVAVVVMVAGITSFGLVTAALAT 92 >4GX0-A nrPDB Length = 565 Score = 34.3 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 27/66 (40%), Gaps = 3/66 (4%) Query: 363 YVYSFYWSTLILTTIGEVPSP-VRNIEYAFVTLDLMCGVLIFATI--VGNVGSMISNMSA 419 ++ YW+ ++TT+G + Y F ++ + GV+ I G V ++ Sbjct: 52 FMAGIYWTITVMTTLGFGDITFESDAGYLFASIVTVSGVIFLDIILPFGFVSMFLAPWIE 111 Query: 420 ARTEFQ 425 R + Sbjct: 112 RRLRYH 117 >5T8N-A nrPDB Length = 139 Score = 33.9 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 65/142 (45%), Gaps = 19/142 (13%) Query: 569 SKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKDNLLDENAP 628 + A VR + +L ++ L + + ++ L KG +++ K NA Sbjct: 3 KNKESPTKAIVRLREHINLLSKKQSHLRTQITNQENEARIFLTKGNKVMAK------NAL 56 Query: 629 EEQKTVEEIAEHLNNAVKVLQTRMARLIVEHSSTEGKLMKRIEMLEKHLSRYKALARRQK 688 +++KT+E++ + ++ ++ ++ +E ++ + M+ ++ A+ K Sbjct: 57 KKKKTIEQLLSKVEGTMESMEQQL--FSIESANLNLETMRAMQ----------EGAKAMK 104 Query: 689 TMH-GVSIDGGDISTDGVDERV 709 T+H G+ ID D + D + E+V Sbjct: 105 TIHSGLDIDKVDETMDEIREQV 126 >2QKS-A nrPDB Length = 321 Score = 33.6 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 30/98 (30%), Gaps = 9/98 (9%) Query: 342 VYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPS-PVRNIEYAFVTLDLMCGV 400 +Y + +F++S L T+G P + TL++ G+ Sbjct: 63 LYMLGSAPIANQFPAGFGG-----AFFFSVETLATVGYGDMHPQTVYAHWIATLEIFVGM 117 Query: 401 LIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELR 438 A G MS + + M + +R Sbjct: 118 SSIALATGCA---FIKMSQPKKRAETLMFSEHAVISMR 152 >2K1E-A nrPDB Length = 103 Score = 33.2 bits (74), Expect = 0.44, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 22/69 (31%), Gaps = 1/69 (1%) Query: 357 DTLLRRYVYSFYWSTLILTTIGEVPS-PVRNIEYAFVTLDLMCGVLIFATIVGNVGSMIS 415 L Y + +WS TT+G PV + G+ +FA + + + Sbjct: 35 GAALISYPDAIWWSVETATTVGYGDRYPVTEEGRKVAEQVMKAGIEVFALVTAALATDFV 94 Query: 416 NMSAARTEF 424 R Sbjct: 95 RREEERRGH 103 >1P7B-A nrPDB Length = 333 Score = 32.8 bits (73), Expect = 0.51, Method: Composition-based stats. Identities = 26/184 (14%), Positives = 56/184 (30%), Gaps = 24/184 (13%) Query: 342 VYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPS-PVRNIEYAFVTLDLMCGV 400 +Y + +V +F++S L T+G P +A TL++ G+ Sbjct: 81 LYQLGDAPIANQSPPG-----FVGAFFFSVETLATVGYGDMHPQTVYAHAIATLEIFVGM 135 Query: 401 LIFATIVGNVGSMISN-----MSAARTEFQ----NKMDGIKQYMELRKVSKQLEIRV--- 448 A G V + + M A + ++ + V + ++ Sbjct: 136 SGIALSTGLVFARFARPRAKIMFARHAIVRPFNGRMTLMVRAANARQNVIAEARAKMRLM 195 Query: 449 -IKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLL--AEL 505 + ++ + + V P L M V +F + L + Sbjct: 196 RREHSSEGYSLMKIHDLKLVRNEHPIFLLGWNMMHV---IDESSPLFGETPESLAEGRAM 252 Query: 506 VLKL 509 +L + Sbjct: 253 LLVM 256 >3E6B-A nrPDB Length = 250 Score = 32.4 bits (72), Expect = 0.66, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 25/54 (46%), Gaps = 3/54 (5%) Query: 511 LQVFSPGDFICKKGDIGREMYIVKRGRLQ---VVDDDGKKVFVTLQEGSVFGEL 561 ++ F+ G + G+ M + G+++ + +D +K+ S+ G+L Sbjct: 34 IRDFAKGSAVIMPGEEITSMIFLVEGKIKLDIIFEDGSEKLLYYAGGNSLIGKL 87 >3SYQ-A nrPDB Length = 340 Score = 32.0 bits (71), Expect = 0.86, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 41/110 (37%), Gaps = 21/110 (19%) Query: 308 RVVVVVWYIVIIIHWN--ACLYFWI----SEWIGLGTDAWVYGHLNKQSLPDDITDTLLR 361 R ++++ +V + W +++ I + + +W ++ Sbjct: 43 RFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSW-------TPCVTNLNG---- 91 Query: 362 RYVYSFYWSTLILTTIGEVPSPVRNI---EYAFVTLDLMCGVLIFATIVG 408 +V +F +S TTIG + + + + + G ++ A +VG Sbjct: 92 -FVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVG 140 >4L3I-A nrPDB Length = 490 Score = 32.0 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 8/100 (8%) Query: 591 SKTDLWNALREYPDARKLLLAKGREILKK--DNLLDENAPEEQKTVEEIAEHLNNAVKVL 648 ++W + P+ ++L + E++KK LLD EE+ E + + ++ K L Sbjct: 25 HLREIWELIGI-PEDQRL---QRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKEL 80 Query: 649 QTRMARLIVEHSSTEGKLMKRIEMLEKHLSRYKALARRQK 688 T + L VE EG+ I LEK L L R+QK Sbjct: 81 NTLCSELHVEPFQEEGE--TTILQLEKDLRTQVELMRKQK 118 >1NL3-A nrPDB Length = 922 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 17/105 (16%), Positives = 39/105 (37%), Gaps = 7/105 (6%) Query: 522 KKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRS 581 ++GD G + + G + +G + L L++ + + A + Sbjct: 603 RQGDPGESRFYLSLGDELMRRFNGAALETLLTR------LNLPDDVPIEAKMVTRAIKSA 656 Query: 582 VGYTDLFVLS-KTDLWNALREYPDARKLLLAKGREILKKDNLLDE 625 + + ++ RK++ A+ R IL+ +NL D+ Sbjct: 657 QTQVEQQNFEVRKNVLKYDEVMNQQRKVIYAERRRILEGENLKDQ 701 >3UKM-A nrPDB Length = 280 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 7/65 (10%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 354 DITDTLLRRYVYSFYWSTLILTTIGEVPS-PVRNIEYAFVTLDLMCGVLIFATIVGNVGS 412 + + + ++++ +L+T G + P+ + AF + + G+ + + Sbjct: 85 QASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFL---TA 141 Query: 413 MISNM 417 ++ + Sbjct: 142 VVQRI 146 >1JI6-A nrPDB Length = 589 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 11/87 (12%) Query: 135 NLLFVIARQVFNDLIGPSSQSLCRFYNGTLNSTTQV--ECT--YNMLTNMKEMPTYSQYP 190 +LL + QVF + G SS+ + FY+ L T Q C YN+ N TY Sbjct: 142 HLLLLKDAQVFGEEWGYSSEDVAEFYHRQLKLTQQYTDHCVNWYNVGLNGLRGSTYD--- 198 Query: 191 DLGWSKYWHFR--MLWVFFDLLMDCVY 215 W K+ FR M DL++ + Sbjct: 199 --AWVKFNRFRREMTLTVLDLIVLFPF 223 >4Z80-A nrPDB Length = 508 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 40/106 (37%), Gaps = 4/106 (3%) Query: 14 STSGLAPTTNGIGSPPPTASAATKFSILTKFLRRKNQVHTTTAQQNEFMQKYMPNGNSNA 73 S+S T +G+P A A + + F +R T +NE MP+ ++ Sbjct: 74 SSSAKIDTKTTVGAPYMAAGACPNYGKVIAFTKRDGSRSDMTRWKNEIHANVMPHSTTS- 132 Query: 74 VQPAATGGQPASSDGGSAIEVPPPKESYAVRIRKYLANYTQDPSTD 119 A+ P +++ +IE Y + Y QD TD Sbjct: 133 ---CASRADPGAAEVAKSIEGFAMYAGYLTHCPYNVNVYRQDMVTD 175 >2H6C-A nrPDB Length = 232 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 31/92 (33%), Gaps = 4/92 (4%) Query: 514 FSPGDFICKKGDIGREMYIVKRGRLQ---VVDDDGKKVFVTLQEGSVFGELSILNIAGSK 570 F+ G I G+ M + G+++ + +D +K+ S+ G L Sbjct: 37 FAKGSAIIMPGEDTTSMIFLMDGKIKLDIIFEDGSEKLLYYAGSNSLIGRLYPTGNNIYA 96 Query: 571 NGNRRTANVRSVGYTDLFVLSKTDLWNALREY 602 +T L V+ +TD + Sbjct: 97 TAMEQTRTCWFSEEC-LRVIFRTDEDMIFEIF 127 >2CWD-A nrPDB Length = 161 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 44/124 (35%), Gaps = 30/124 (24%) Query: 490 KVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVF 549 + + + LL E L+ + +V S G G+ ++V Sbjct: 17 RSPMAEGIFRKLLKERGLEDRFEVDSAGTGAWHVGEPMD--------------PRARRVL 62 Query: 550 VTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDAR--- 606 EG+ F + RR + Y + V+ + +L LR +P+AR Sbjct: 63 EE--EGAYF-----------PHVARRLTREDVLAYDHILVMDRENLEEVLRRFPEARGKV 109 Query: 607 KLLL 610 +L+L Sbjct: 110 RLVL 113 >6AIO-A nrPDB Length = 418 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 14 STSGLAPTTNGIGSPPPTASAATKFSILTKFLRR 47 S SG++P+ + PPTA+A +F +L +R Sbjct: 43 SESGVSPSPRAVAYMPPTAAALDRFGLLDDIRKR 76 >5FIL-H nrPDB Length = 146 Score = 31.2 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 20/51 (39%), Gaps = 2/51 (3%) Query: 500 GLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFV 550 G+LA V LQ V PG + D Y V G + V D ++ Sbjct: 46 GILAAHVPTLQ--VLRPGLVVVHAEDGTTSKYFVSSGSVTVNADSSVQLLA 94 >2W6I-H nrPDB Length = 168 Score = 31.2 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 20/51 (39%), Gaps = 2/51 (3%) Query: 500 GLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFV 550 G+LA V LQ V PG + D Y V G + V D ++ Sbjct: 68 GILAAHVPTLQ--VLRPGLVVVHAEDGTTSKYFVSSGSVTVNADSSVQLLA 116 >3RVY-A nrPDB Length = 285 Score = 30.9 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 35/219 (15%), Positives = 72/219 (32%), Gaps = 43/219 (19%) Query: 200 FRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIP 259 F + F+ ++ ++ I+ L + K W + + ISL+P Sbjct: 59 FGVYTTLFNQIVITIFTIEIIL----------RIYVHRISFFKDPWSLFDFFVVAISLVP 108 Query: 260 LDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSS-----MPNAFRVVVVVW 314 G ILR+ R++R R+ + + S +P V+ ++ Sbjct: 109 ------------TSSGFEILRVLRVLRLFRLVTAVPQMRKIVSALISVIPGMLSVIALMT 156 Query: 315 YIVIIIHWNACLYFWISEWIGLGTDA----WVYGHLNKQSLPDDITDTLLRRYVYSFYWS 370 I A F GT ++ + +S I L+ Y Y++ + Sbjct: 157 LFFYIFAIMATQLFGERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVFF 216 Query: 371 TLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGN 409 + + FV ++L+ + + A + N Sbjct: 217 IPFIFVV------------TFVMINLVVAICVDAMAILN 243 >4RYU-A nrPDB Length = 267 Score = 30.9 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 22/126 (17%), Positives = 40/126 (31%), Gaps = 9/126 (7%) Query: 504 ELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSI 563 L L+ F GD + G +Y+ G ++ V + G G+ I Sbjct: 60 TLESSLRTFTFDNGDIAVQMGTPTDCVYL---GVNALMRPRPDIVVSGINAGPNLGDDVI 116 Query: 564 LNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKDNLL 623 + + R ++ +S + LL RE L+ +L Sbjct: 117 YSGTVAAAMAGRHLGFPALA------VSLNGYQHYDTAAAVTCALLRGLSREPLRTGRIL 170 Query: 624 DENAPE 629 + N P+ Sbjct: 171 NVNVPD 176 >2NLJ-C nrPDB Length = 124 Score = 30.9 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 33/95 (34%), Gaps = 6/95 (6%) Query: 319 IIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIG 378 +HW A + I L +++ + + L Y + +WS TT+G Sbjct: 23 ALHWRAAGAATVLLVIVLLAGSYLAVLAERGAP-----GAQLITYPRALWWSVETATTVG 77 Query: 379 EVP-SPVRNIEYAFVTLDLMCGVLIFATIVGNVGS 412 PV + ++ G+ F + + + Sbjct: 78 YGDLYPVTLWGRCVAVVVVVAGITSFGLVTAALAT 112 >2XSP-A nrPDB Length = 440 Score = 30.5 bits (67), Expect = 2.4, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 3/42 (7%) Query: 28 PPPTASAATKFSILTKFLRRKNQVHTTTAQQNEFMQKYMPNG 69 P T + +KF+++T+FL N TTT +E + Y+ NG Sbjct: 276 PGKTVNTNSKFTVVTQFLTSDN---TTTGTLHEIRRLYVQNG 314 >5E44-A nrPDB Length = 259 Score = 30.5 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 22/145 (15%), Positives = 56/145 (38%), Gaps = 16/145 (11%) Query: 494 FQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQ---VVDDDGKKVFV 550 D E L E++ + + G + K GD + +Y ++ G ++ + + +++ Sbjct: 43 LNDSELDQLDEIIERKKP--IQKGQELFKAGDELKCLYAIRSGTIKSYTITEQGDEQITA 100 Query: 551 TLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLL 610 G + G +I + + +++ + + + L + + P R+ ++ Sbjct: 101 FHLAGDLVGFDAI-------TEAQHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIM 153 Query: 611 AKGREILKKDN----LLDENAPEEQ 631 +K D LL + EE+ Sbjct: 154 RLMSNEIKGDQEMILLLSKKNAEER 178 >4QJ3-B nrPDB Length = 793 Score = 30.5 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 14/113 (12%) Query: 595 LWNALREYPDARKLLL---AKGREILKKDNLLDE-NAPEEQKTVEEIAEHLNNAVKVLQT 650 N L PD K+LL AKG+ L + L+D N + + E+ L+ Sbjct: 217 FLNKLCLRPDIDKILLEIGAKGKPYLTLEQLMDFINQKQRDPRLNEVL------YPPLRP 270 Query: 651 RMARLIVEHSSTEGKLMKRIEMLEKHLSRYKALARRQKTMHGVSIDGGDISTD 703 ARL++E + ++R +M + SRY L + + + ++ D+STD Sbjct: 271 SQARLLIEKYEPNQQFLERDQMSMEGFSRY--LGGEENGI--LPLEALDLSTD 319 >3OHM-B nrPDB Length = 885 Score = 30.5 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 14/113 (12%) Query: 595 LWNALREYPDARKLLL---AKGREILKKDNLLDE-NAPEEQKTVEEIAEHLNNAVKVLQT 650 N L PD K+LL AKG+ L + L+D N + + E+ L+ Sbjct: 215 FLNKLCLRPDIDKILLEIGAKGKPYLTLEQLMDFINQKQRDPRLNEVL------YPPLRP 268 Query: 651 RMARLIVEHSSTEGKLMKRIEMLEKHLSRYKALARRQKTMHGVSIDGGDISTD 703 ARL++E + ++R +M + SRY L + + + ++ D+STD Sbjct: 269 SQARLLIEKYEPNQQFLERDQMSMEGFSRY--LGGEENGI--LPLEALDLSTD 317 >4OB1-A nrPDB Length = 290 Score = 30.5 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 27/50 (54%), Gaps = 7/50 (14%) Query: 603 PDARKLLLAKGREILKKDNLLDENAPEEQKTVEEIAEHLNNAVKVLQTRM 652 P+ +K LLA G E +N+L +K+ EEI + + VK L++ + Sbjct: 66 PEFKKRLLADGTEACMTENIL-------RKSDEEIQKEITARVKALESML 108 >6C96-A nrPDB Length = 825 Score = 30.5 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 24/103 (23%) Query: 109 LANYTQDPSTDNFYYWTCVVTVAY-------IYNLLFVIARQVFNDLIGPSSQSLCRFYN 161 + +Y+++P W+CV + Y I NLL + FND+ +SL Sbjct: 288 MPSYSRNP-------WSCVFFIVYLSIELYFIMNLLLAVVFDTFNDIEKHKFKSL----- 335 Query: 162 GTLNSTTQVECTYNMLTNMKEMP--TYSQYPDLGWSKYWHFRM 202 L+ T ++ Y +L + + +Y Q+ G +++ RM Sbjct: 336 -LLHKRTAIQHAYGLLASQRRPAGISYRQFE--GLMRFYKPRM 375 >3SPG-A nrPDB Length = 343 Score = 30.1 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 47/123 (38%), Gaps = 26/123 (21%) Query: 309 VVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFY 368 + ++++++ +IH + G D + + +V +F Sbjct: 61 LFGLIFWLIALIH---------GDLENPGGDD------TFKPCVLQVNG-----FVAAFL 100 Query: 369 WSTLILTTIGEVPSPVRN---IEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQ 425 +S TTIG V + V + + G +I + ++G ++++ M+A + Q Sbjct: 101 FSIETQTTIGYGFRCVTEECPLAVFMVVVQSIVGCIIDSFMIG---AIMAKMAAPKKRAQ 157 Query: 426 NKM 428 + Sbjct: 158 TLL 160 >5M3Y-A nrPDB Length = 458 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 27/64 (42%) Query: 551 TLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLL 610 L +VFG L+ L + + R + V + D S+ D L + LL+ Sbjct: 100 VLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKQCTSRLDAHKVLSALQAVQGLLV 159 Query: 611 AKGR 614 A+GR Sbjct: 160 AQGR 163 >3THY-A nrPDB Length = 934 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 38/160 (23%), Positives = 61/160 (38%), Gaps = 26/160 (16%) Query: 547 KVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDAR 606 K L + S FG+ + S+ A VR++ +LF S D + Sbjct: 275 KFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRAL---NLFQGSVEDTTGSQSLAALLN 331 Query: 607 KLLLAKGREILK---KDNLLDENAPEEQ-KTVEEIAE-----------------HLNNAV 645 K +G+ ++ K L+D+N EE+ VE E LN Sbjct: 332 KCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLA 391 Query: 646 KVLQTRMARLIVEHSSTEG--KLMKRIEMLEKHLSRYKAL 683 K Q + A L + +G +L I+ LEKH +++ L Sbjct: 392 KKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKL 431 >3ACP-A nrPDB Length = 417 Score = 29.7 bits (65), Expect = 4.7, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 30/99 (30%), Gaps = 16/99 (16%) Query: 509 LQLQVFSPGDFICKKGDIGREMY------IVKRG-----RLQVVDDDGKKVFVTLQEGSV 557 L+ G+F+ +G +Y V G +L ++ D + E Sbjct: 317 LRSPECPVGEFLINEGTPINNVYFAAGALFVSSGFDTSIKLDIISDPESERPAIEFETPT 376 Query: 558 F-----GELSILNIAGSKNGNRRTANVRSVGYTDLFVLS 591 F E+S N V + L+ LS Sbjct: 377 FLVSNDDEVSQFCYVSDDESNGEVLEVGKNNFCALYNLS 415 >5XIX-A nrPDB Length = 472 Score = 29.3 bits (64), Expect = 6.3, Method: Composition-based stats. Identities = 16/43 (37%), Positives = 21/43 (48%) Query: 135 NLLFVIARQVFNDLIGPSSQSLCRFYNGTLNSTTQVECTYNML 177 NL+F++ R L + LC+ YNG L ST Y ML Sbjct: 67 NLMFLVLRDGTGYLQCVLADELCQCYNGVLLSTESSVAVYGML 109 >2E1D-A nrPDB Length = 331 Score = 28.9 bits (63), Expect = 9.1, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 40/104 (38%), Gaps = 10/104 (9%) Query: 542 DDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALRE 601 D K V FG +I+ A R T ++++ D +S L L++ Sbjct: 208 DPGVKSVTKIYNYYKKFGYKTIVMGA----SFRNTGEIKALAGCDFLTISPKLLGELLKD 263 Query: 602 YPDARKLLLAKGREILKKDNL-LDENA-----PEEQKTVEEIAE 639 L K + + + LDE A E+Q VE++++ Sbjct: 264 NSKLAPALSVKAAQTSDSEKIHLDEKAFRWLHNEDQMAVEKLSD 307 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.129 0.351 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,567,526 Number of Sequences: 36641 Number of extensions: 1080465 Number of successful extensions: 3350 Number of sequences better than 10.0: 104 Number of HSP's better than 10.0 without gapping: 83 Number of HSP's successfully gapped in prelim test: 79 Number of HSP's that attempted gapping in prelim test: 3083 Number of HSP's gapped (non-prelim): 205 length of query: 733 length of database: 10,336,785 effective HSP length: 104 effective length of query: 629 effective length of database: 6,526,121 effective search space: 4104930109 effective search space used: 4104930109 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 63 (28.9 bits)