BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q03532 (505 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6CB1-p nrPDB 1041 0.0 3LY5-A nrPDB 285 4e-77 3I62-A nrPDB 228 5e-60 3SQW-A nrPDB 224 6e-59 5IVL-B nrPDB 212 4e-55 2PL3-A nrPDB 198 4e-51 2DB3-A nrPDB 193 2e-49 4D25-A nrPDB 191 4e-49 2I4I-A nrPDB 189 3e-48 4BRW-A nrPDB 188 5e-48 6CZ5-A nrPDB 187 8e-48 1HV8-A nrPDB 186 2e-47 4NHO-A nrPDB 182 3e-46 3JCR-F nrPDB 180 1e-45 5DTU-A nrPDB 177 8e-45 4LJY-A nrPDB 177 9e-45 5ANR-B nrPDB 176 2e-44 2Z0M-A nrPDB 176 3e-44 4KBG-A nrPDB 172 2e-43 5ZWN-y nrPDB 168 6e-42 2HYI-C nrPDB 167 1e-41 4W7S-A nrPDB 167 1e-41 3EIQ-A nrPDB 165 5e-41 1XTI-A nrPDB 159 3e-39 3BER-A nrPDB 155 5e-38 5SUQ-A nrPDB 151 6e-37 5SUP-A nrPDB 150 1e-36 2VSX-A nrPDB 149 3e-36 5H1Y-A nrPDB 137 1e-32 5GVS-A nrPDB 136 2e-32 6B4I-E nrPDB 135 5e-32 6AIC-A nrPDB 134 7e-32 3PEW-A nrPDB 131 8e-31 3FE2-A nrPDB 131 9e-31 1WRB-A nrPDB 127 9e-30 4PX9-A nrPDB 127 1e-29 2GXQ-A nrPDB 125 5e-29 5GJU-A nrPDB 122 3e-28 3IUY-A nrPDB 122 5e-28 5ZBZ-A nrPDB 117 9e-27 3FHO-A nrPDB 116 2e-26 3BOR-A nrPDB 114 1e-25 1VEC-A nrPDB 107 1e-23 1QVA-A nrPDB 105 4e-23 1Q0U-A nrPDB 100 1e-21 3DKP-A nrPDB 98 8e-21 1T6N-A nrPDB 94 1e-19 2OXC-A nrPDB 84 2e-16 3FHC-B nrPDB 83 2e-16 3FMO-B nrPDB 83 2e-16 2KBE-A nrPDB 79 6e-15 6CRM-A nrPDB 74 1e-13 1OYY-A nrPDB 66 3e-11 4Q48-A nrPDB 65 8e-11 5V9X-A nrPDB 50 2e-06 1WP9-A nrPDB 48 9e-06 5LST-A nrPDB 44 1e-04 1GM5-A nrPDB 41 0.001 2FWR-A nrPDB 41 0.001 5X0Y-O nrPDB 39 0.007 4CDG-A nrPDB 38 0.012 2VA8-A nrPDB 37 0.015 5K9T-A nrPDB 37 0.027 2FSI-A nrPDB 37 0.029 3BXZ-A nrPDB 36 0.048 6BOG-A nrPDB 35 0.11 2NMV-A nrPDB 33 0.34 4A2W-A nrPDB 33 0.42 4A2Q-A nrPDB 32 0.54 4A36-A nrPDB 32 0.70 2WWY-A nrPDB 31 0.97 6G19-A nrPDB 31 1.4 1D9Z-A nrPDB 30 1.7 1TF2-A nrPDB 30 2.6 5TNU-A nrPDB 30 3.1 5JCF-A nrPDB 30 3.1 3B6E-A nrPDB 30 3.3 5JBJ-A nrPDB 30 3.5 6FWS-A nrPDB 29 4.0 5EUL-A nrPDB 29 4.8 4GYK-A nrPDB 29 6.0 >6CB1-p nrPDB Length = 505 Score = 1041 bits (2693), Expect = 0.0, Method: Compositional matrix adjust. Identities = 505/505 (100%), Positives = 505/505 (100%) Query: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM 60 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM Sbjct: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM 60 Query: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI Sbjct: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 Query: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ Sbjct: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 Query: 181 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR 240 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR Sbjct: 181 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR 240 Query: 241 ISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCN 300 ISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCN Sbjct: 241 ISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCN 300 Query: 301 SVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDW 360 SVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDW Sbjct: 301 SVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDW 360 Query: 361 IIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPEN 420 IIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPEN Sbjct: 361 IIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPEN 420 Query: 421 KIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAKVAKSYGFP 480 KIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAKVAKSYGFP Sbjct: 421 KIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAKVAKSYGFP 480 Query: 481 VPPKVNITIGASGKTPNTKRRKTHK 505 VPPKVNITIGASGKTPNTKRRKTHK Sbjct: 481 VPPKVNITIGASGKTPNTKRRKTHK 505 >3LY5-A nrPDB Length = 262 Score = 285 bits (728), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 130/202 (64%), Positives = 174/202 (86%), Gaps = 1/202 (0%) Query: 49 LSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLK 108 +++ TLKAI++MGFT MT +Q ++I PLL GRD+L AAKTGSGKTLAFLIPA+EL+ L+ Sbjct: 61 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 120 Query: 109 FKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNML 168 F PRNGTG+++++PTRELA+Q FGV +ELM H T+G+++GG+NR EA+KL G+N++ Sbjct: 121 FMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINII 180 Query: 169 IATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFS 228 +ATPGRLLDH+QNT GF++KNL+ L+IDEADRIL++GFE+E++QIIK+LP RQ+MLFS Sbjct: 181 VATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTR-RQTMLFS 239 Query: 229 ATQTTKVEDLARISLRPGPLFI 250 ATQT KVEDLARISL+ PL++ Sbjct: 240 ATQTRKVEDLARISLKKEPLYV 261 >3I62-A nrPDB Length = 563 Score = 228 bits (581), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 155/435 (35%), Positives = 237/435 (54%), Gaps = 36/435 (8%) Query: 5 SNKRSRDSESTEEPVVDEKSTSKQNNAAPE--GEQTTCVEKFEELKLSQPTLKAIEKMGF 62 S R+R E +E D+ + SK + E ++ T EE L + KAI +M F Sbjct: 33 SRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEF 92 Query: 63 TTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 +T VQ +TI P+L+ DV+ AKTG+GKT AFLIP + L + KF + +++ Sbjct: 93 PGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIV 152 Query: 121 TPTRELALQIFGVARELMEFHSQTFGI-------VIGGANRRQEAEKLMK-GVNMLIATP 172 PTR+LALQI E+ + H +G+ ++GG + R K+ K N++IATP Sbjct: 153 APTRDLALQI---EAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATP 209 Query: 173 GRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQS------ML 226 GRL+D L+ F+ + ++DEADR+LEIGF D++ I IL ++ +S +L Sbjct: 210 GRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLL 269 Query: 227 FSATQTTKVEDLAR-ISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLK 285 FSAT KV+ LA I + LF++ V + + + ++Q V+ S+K +F+ ++ Sbjct: 270 FSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVI--SEKFANSIFAAVE 327 Query: 286 --------RNQKKKIIVFLSSCNSVKYYAELLNY---IDLPVLELHGKQKQQKRTNTFFE 334 R+ K I+F + + +L DLP+LE HGK Q KRT+ Sbjct: 328 HIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKR 387 Query: 335 FCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFL 394 F E GIL+CTDV ARG+D P V ++Q P + +YIHR+GRTAR K +G S++F+ Sbjct: 388 FKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGK-EGSSVLFI 446 Query: 395 TPNELGFLRYLKASK 409 +EL F+R L+ +K Sbjct: 447 CKDELPFVRELEDAK 461 >3SQW-A nrPDB Length = 579 Score = 224 bits (572), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 145/394 (36%), Positives = 220/394 (55%), Gaps = 34/394 (8%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLIPAI 101 EE L + KAI +M F +T VQ +TI P+L+ DV+ AKTG+GKT AFLIP Sbjct: 23 LEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIF 82 Query: 102 ELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGI-------VIGGANR 154 + L + KF + +++ PTR+LALQI E+ + H +G+ ++GG + Sbjct: 83 QHLINTKFDSQYMVKAVIVAPTRDLALQI---EAEVKKIHDMNYGLKKYACVSLVGGTDF 139 Query: 155 RQEAEKLMK-GVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQI 213 R K+ K N++IATPGRL+D L+ F+ + ++DEADR+LEIGF D++ I Sbjct: 140 RAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETI 199 Query: 214 IKILPNEDRQS------MLFSATQTTKVEDLAR-ISLRPGPLFINVVPETDNSTADGLEQ 266 IL ++ +S +LFSAT KV+ LA I + LF++ V + + + ++Q Sbjct: 200 SGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQ 259 Query: 267 GYVVCDSDKRFLLLFSFLK--------RNQKKKIIVFLSSCNSVKYYAELLNY---IDLP 315 V+ S+K +F+ ++ R+ K I+F + + +L DLP Sbjct: 260 SVVI--SEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLP 317 Query: 316 VLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIH 375 +LE HGK Q KRT+ F E GIL+CTDV ARG+D P V ++Q P + +YIH Sbjct: 318 ILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIH 377 Query: 376 RVGRTARGTKGKGKSLMFLTPNELGFLRYLKASK 409 R+GRTAR K +G S++F+ +EL F+R L+ +K Sbjct: 378 RIGRTARSGK-EGSSVLFICKDELPFVRELEDAK 410 >5IVL-B nrPDB Length = 429 Score = 212 bits (539), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 134/367 (36%), Positives = 203/367 (55%), Gaps = 18/367 (4%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F+EL LSQ +KAIE+MGF T +QA+TIP L +DV+G A+TG+GKT AF IP +E Sbjct: 4 FQELGLSQEVMKAIERMGFEETTPIQAKTIPLSLQNKDVIGQAQTGTGKTAAFGIPIVE- 62 Query: 104 LHSLKFKPRNGT-GIIVITPTRELALQIFGVARELMEFHSQTFGIVI---GGANRRQEAE 159 K +NG +V+ PTRELA+Q V+ EL + + V+ GG + ++ Sbjct: 63 ----KVDVKNGAIQALVVAPTRELAIQ---VSEELYKIGAVKRVRVLPIYGGQDIERQIR 115 Query: 160 KLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPN 219 L K ++++ TPGR++DH+ N +++ +++DEAD +L +GF +++ I+ +P Sbjct: 116 ALKKHPHVIVGTPGRIIDHI-NRGTLRLEHVHTVVLDEADEMLNMGFIEDIEAILSHVPA 174 Query: 220 EDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLL 279 E RQ++LFSAT + +A + P + V + T ++Q Y+ K+F + Sbjct: 175 E-RQTLLFSATMPDPIRRIAERFMNE-PELVKV--KAKEMTVPNIQQYYLEVHEKKKFDI 230 Query: 280 LFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAE 339 L L + IVF + V AE LN +HG Q KR + +F Sbjct: 231 LTRLLDIQAPELAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLSQAKRLSVLRKFKEGA 290 Query: 340 RGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNEL 399 IL+ TDVAARGLDI V + FD P DP Y+HR+GRT R K G ++ F+TP E+ Sbjct: 291 IEILVATDVAARGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGK-TGVAMTFVTPREI 349 Query: 400 GFLRYLK 406 G L +++ Sbjct: 350 GQLHHIE 356 >2PL3-A nrPDB Length = 236 Score = 198 bits (504), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 99/212 (46%), Positives = 151/212 (71%), Gaps = 3/212 (1%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 + +F + LS+ TLK +++ + +T +Q +TI L G+DVLGAAKTGSGKTLAFL+P Sbjct: 24 ITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPV 83 Query: 101 IELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEK 160 +E L+ L++ +G G+++I+PTRELA Q F V R++ + H + G++IGG + + EAE+ Sbjct: 84 LEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAER 143 Query: 161 LMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNE 220 + +N+L+ TPGRLL H+ T F +L+ L++DEADRIL++GF D M +I+ LP + Sbjct: 144 I-NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKK 202 Query: 221 DRQSMLFSATQTTKVEDLARISLRPGPLFINV 252 RQ++LFSATQT V+DLAR+SL+ P ++ V Sbjct: 203 -RQTLLFSATQTKSVKDLARLSLK-NPEYVWV 232 >2DB3-A nrPDB Length = 434 Score = 193 bits (490), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 118/359 (32%), Positives = 198/359 (55%), Gaps = 16/359 (4%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 ++ F L + + K G+ T +Q +IP + +GRD++ A+TGSGKT AFL+P Sbjct: 55 IQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPI 114 Query: 101 IELL----HSLKF-KPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRR 155 + L H L+ +P+ +++++PTRELA+QIF AR+ GIV GG + R Sbjct: 115 LSKLLEDPHELELGRPQ----VVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFR 170 Query: 156 QEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQII- 214 + E + +G +++IATPGRLLD + T F++ + +++DEADR+L++GF ++MR+I+ Sbjct: 171 HQNECITRGCHVVIATPGRLLDFVDRTF-ITFEDTRFVVLDEADRMLDMGFSEDMRRIMT 229 Query: 215 KILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSD 274 + + Q+++FSAT +++ +A L+ +F+ + + +D + Y V Sbjct: 230 HVTMRPEHQTLMFSATFPEEIQRMAGEFLK-NYVFV-AIGIVGGACSDVKQTIYEVNKYA 287 Query: 275 KRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFE 334 KR L+ + Q IVF+ + + A L+ + P +HG + Q +R + Sbjct: 288 KRSKLIE--ILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRD 345 Query: 335 FCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR-GTKGKGKSLM 392 F N +LI T VA+RGLDI + +I +D P DY+HR+GRT R G G+ S Sbjct: 346 FKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFF 404 >4D25-A nrPDB Length = 434 Score = 191 bits (486), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 117/360 (32%), Positives = 197/360 (54%), Gaps = 13/360 (3%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 +E FE L + L + K G+ T +Q IP +++GRD++G A+TGSGKT AFL+P Sbjct: 49 IESFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTGSGKTAAFLVPI 108 Query: 101 IELL--HSLKFKPRNGTG---IIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRR 155 I +L NG +I+++PTREL LQIF AR+ + GG R Sbjct: 109 INMLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNEARKFSYGSVLKVAVAYGGTAVR 168 Query: 156 QEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQII- 214 + + + +G ++L+ATPGRL D ++ + F +++ +++D+AD +L++GF + +++ Sbjct: 169 HQGDNIARGCHILVATPGRLHDFVERNR-VSFGSVRFVVLDQADCMLDMGFMPSIEKMML 227 Query: 215 --KILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCD 272 ++ RQ+++FSAT ++ LA L LF+ V ST +EQ ++ Sbjct: 228 HPTMVETTKRQTLMFSATFPEDIQHLAGRFLN-NYLFVAVGIVGGAST--DVEQIFIEVT 284 Query: 273 SDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTF 332 ++ L ++ N K+I+VF+ + + + A +L+ L +HG + Q++R Sbjct: 285 KYEKRNSLKQLIEENDGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEAL 344 Query: 333 FEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR-GTKGKGKSL 391 F + + IL+ T VAARGLDI VD ++ +D P +Y+HR+GRT R G +GK S Sbjct: 345 QNFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRVGNRGKAVSF 404 >2I4I-A nrPDB Length = 417 Score = 189 bits (479), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 128/373 (34%), Positives = 198/373 (53%), Gaps = 30/373 (8%) Query: 29 NNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKT 88 NN P +E F ++++ + + IE +T T VQ IP + RD++ A+T Sbjct: 8 NNCPPH------IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQT 61 Query: 89 GSGKTLAFLIPAI---------ELLHSLKFKPRNGTG-----IIVITPTRELALQIFGVA 134 GSGKT AFL+P + E L ++K R G +V+ PTRELA+QI+ A Sbjct: 62 GSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEA 121 Query: 135 RELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTK-GFVFKNLKAL 193 R+ +V GGA+ Q+ L +G ++L+ATPGRL+D ++ K G F K L Sbjct: 122 RKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDF--CKYL 179 Query: 194 IIDEADRILEIGFEDEMRQIIK---ILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFI 250 ++DEADR+L++GFE ++R+I++ + P R +M+FSAT +++ LAR L +I Sbjct: 180 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDE---YI 236 Query: 251 NVVPETDNSTADGLEQGYV-VCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELL 309 + ST++ + Q V V +SDKR LL + +VF+ + + L Sbjct: 237 FLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFL 296 Query: 310 NYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDD 369 + +HG + Q+ R +F + + IL+ T VAARGLDI V +I FD P D Sbjct: 297 YHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSD 356 Query: 370 PRDYIHRVGRTAR 382 +Y+HR+GRT R Sbjct: 357 IEEYVHRIGRTGR 369 >4BRW-A nrPDB Length = 377 Score = 188 bits (477), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 118/340 (34%), Positives = 180/340 (52%), Gaps = 12/340 (3%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 FE+ L + L I + GF + +Q IP + GRD+L AK G+GKT AF+IP +E Sbjct: 3 FEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTLE- 61 Query: 104 LHSLKFKPR-NGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLM 162 K KP+ N +++ PTRELALQ V R L + + + GG N R + +L Sbjct: 62 ----KVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHCGISCMVTTGGTNLRDDILRLN 117 Query: 163 KGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDR 222 + V++L+ TPGR+LD L + K + I+DEAD++L F+ + QI+ LP Sbjct: 118 ETVHILVGTPGRVLD-LASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLP-PTH 175 Query: 223 QSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFS 282 QS+LFSAT V++ L P IN++ E T G+ Q Y + ++ L + Sbjct: 176 QSLLFSATFPLTVDEFMDKHLHK-PYEINLMEEL---TLKGITQYYAFVEERQKLHCLNT 231 Query: 283 FLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGI 342 + Q + I+F +S N V+ A+ + + H + KQQ+R F EF + Sbjct: 232 LFSKLQINQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRT 291 Query: 343 LICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR 382 L+C+D+ RG+DI AV+ +I FD P Y+HR+GR+ R Sbjct: 292 LVCSDLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGR 331 >6CZ5-A nrPDB Length = 480 Score = 187 bits (475), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 127/373 (34%), Positives = 197/373 (52%), Gaps = 30/373 (8%) Query: 29 NNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKT 88 NN P +E F ++++ + + IE +T T VQ IP + RD++ A+T Sbjct: 46 NNCPPH------IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQT 99 Query: 89 GSGKTLAFLIPAI---------ELLHSLKFKPRNGTG-----IIVITPTRELALQIFGVA 134 G GKT AFL+P + E L ++K R G +V+ PTRELA+QI+ A Sbjct: 100 GCGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEA 159 Query: 135 RELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTK-GFVFKNLKAL 193 R+ +V GGA+ Q+ L +G ++L+ATPGRL+D ++ K G F K L Sbjct: 160 RKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDF--CKYL 217 Query: 194 IIDEADRILEIGFEDEMRQIIK---ILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFI 250 ++DEADR+L++GFE ++R+I++ + P R +M+FSAT +++ LAR L +I Sbjct: 218 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDE---YI 274 Query: 251 NVVPETDNSTADGLEQGYV-VCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELL 309 + ST++ + Q V V +SDKR LL + +VF+ + + L Sbjct: 275 FLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFL 334 Query: 310 NYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDD 369 + +HG + Q+ R +F + + IL+ T VAARGLDI V +I FD P D Sbjct: 335 YHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSD 394 Query: 370 PRDYIHRVGRTAR 382 +Y+HR+GRT R Sbjct: 395 IEEYVHRIGRTGR 407 >1HV8-A nrPDB Length = 367 Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 127/376 (33%), Positives = 198/376 (52%), Gaps = 19/376 (5%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGR-DVLGAAKTGSGKTLAFLIPAIE 102 F EL LS L AI GF T +Q + IP L +++ A+TGSGKT +F IP IE Sbjct: 8 FNELNLSDNILNAIRNKGFEKPTDIQMKVIPLFLNDEYNIVAQARTGSGKTASFAIPLIE 67 Query: 103 LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLM 162 L++ NG I++TPTRELA+Q+ L + + GG + K + Sbjct: 68 LVNE-----NNGIEAIILTPTRELAIQVADEIESLKGNKNLKIAKIYGGKAIYPQI-KAL 121 Query: 163 KGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDR 222 K N+++ TPGR+LDH+ N KN+K I+DEAD +L +GF ++ +I+ N+D+ Sbjct: 122 KNANIVVGTPGRILDHI-NRGTLNLKNVKYFILDEADEMLNMGFIKDVEKILNAC-NKDK 179 Query: 223 QSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFS 282 + +LFSAT ++ +LA+ + FI + +EQ YV + ++RF L Sbjct: 180 RILLFSATMPREILNLAKKYMGDYS-FIKAKINAN------IEQSYVEVNENERFEALCR 232 Query: 283 FLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGI 342 LK N++ +VF + K A +L I +HG Q +R F + I Sbjct: 233 LLK-NKEFYGLVFCKTKRDTKELASMLRDIGFKAGAIHGDLSQSQREKVIRLFKQKKIRI 291 Query: 343 LICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFL 402 LI TDV +RG+D+ ++ +I + P +P Y+HR+GRT R K KGK++ + E L Sbjct: 292 LIATDVMSRGIDVNDLNCVINYHLPQNPESYMHRIGRTGRAGK-KGKAISIINRREYKKL 350 Query: 403 RYL-KASKVPLNEYEF 417 RY+ +A K+ + + +F Sbjct: 351 RYIERAMKLKIKKLKF 366 >4NHO-A nrPDB Length = 488 Score = 182 bits (462), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 131/404 (32%), Positives = 210/404 (51%), Gaps = 47/404 (11%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 + +++ L L+ I+K G+ T +Q + IP L RD++G A+TGSGKT AFLIP Sbjct: 58 IRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPL 117 Query: 101 IELLHSLKFKPR-----NGTGIIVITPTRELALQIFGVARELMEFHSQTFGI----VIGG 151 + + +L R G I++ PTRELA QI E ++F + GI VIGG Sbjct: 118 LVWITTLPKIDRIEESDQGPYAIILAPTRELAQQI---EEETIKF-GKPLGIRTVAVIGG 173 Query: 152 ANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMR 211 +R + +L G ++IATPGRL+D L+N + V +++DEADR++++GFE +++ Sbjct: 174 ISREDQGFRLRMGCEIVIATPGRLIDVLEN-RYLVLSRCTYVVLDEADRMIDMGFEPDVQ 232 Query: 212 QIIKILP----------NED---------------RQSMLFSATQTTKVEDLARISLR-P 245 +I++ +P ED RQ+++F+AT VE LAR LR P Sbjct: 233 KILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRP 292 Query: 246 GPLFINVVPETDNSTADGLEQG-YVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKY 304 ++I + + +EQ +++ +S+KR LL + L++ II+F++ Sbjct: 293 AVVYIG----SAGKPHERVEQKVFLMSESEKRKKLL-AILEQGFDPPIIIFVNQKKGCDV 347 Query: 305 YAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQF 364 A+ L + LHG + Q++R + IL+ TDVA RG+DI V ++ + Sbjct: 348 LAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNY 407 Query: 365 DPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKAS 408 D + DYIHR+GRT R K G ++ FLT + LK + Sbjct: 408 DMAKNIEDYIHRIGRTGRAGKS-GVAITFLTKEDSAVFYELKQA 450 >3JCR-F nrPDB Length = 820 Score = 180 bits (457), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 130/391 (33%), Positives = 204/391 (52%), Gaps = 47/391 (12%) Query: 54 LKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPR- 112 L+ I+K G+ T +Q + IP L RD++G A+TGSGKT AFLIP + + +L R Sbjct: 403 LEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRI 462 Query: 113 ----NGTGIIVITPTRELALQIFGVARELMEFHSQTFGI----VIGGANRRQEAEKLMKG 164 G I++ PTRELA QI E ++F + GI VIGG +R + +L G Sbjct: 463 EESDQGPYAIILAPTRELAQQI---EEETIKF-GKPLGIRTVAVIGGISREDQGFRLRMG 518 Query: 165 VNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILP------ 218 ++IATPGRL+D L+N + V +++DEADR++++GFE ++++I++ +P Sbjct: 519 CEIVIATPGRLIDVLEN-RYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKP 577 Query: 219 ----NED---------------RQSMLFSATQTTKVEDLARISLR-PGPLFINVVPETDN 258 ED RQ+++F+AT VE LAR LR P ++I Sbjct: 578 DTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSA----G 633 Query: 259 STADGLEQG-YVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVL 317 + +EQ +++ +S+KR LL + L++ II+F++ A+ L + Sbjct: 634 KPHERVEQKVFLMSESEKRKKLL-AILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNAC 692 Query: 318 ELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRV 377 LHG + Q++R + IL+ TDVA RG+DI V ++ +D + DYIHR+ Sbjct: 693 TLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRI 752 Query: 378 GRTARGTKGKGKSLMFLTPNELGFLRYLKAS 408 GRT R K G ++ FLT + LK + Sbjct: 753 GRTGRAGKS-GVAITFLTKEDSAVFYELKQA 782 >5DTU-A nrPDB Length = 475 Score = 177 bits (450), Expect = 8e-45, Method: Compositional matrix adjust. Identities = 128/417 (30%), Positives = 207/417 (49%), Gaps = 44/417 (10%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 +EE L + L + ++G+ T +Q IP L RD++G A TGSGKT AFL+P + Sbjct: 44 WEESGLPRRLLDIVYRVGYDEPTPIQRAAIPIALQARDLIGVAVTGSGKTAAFLLPLLVY 103 Query: 104 LHSL----KFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAE 159 + L ++ +G +++ PTREL QI AR+ + T ++GG + ++A Sbjct: 104 ISELPPLTEYNKNDGPYALILAPTRELVQQIESEARKFADPLGFTVVSIVGGHSLEEQAF 163 Query: 160 KLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILP- 218 L G +++ATPGRL+D ++ + VF +I+DEADR+++ GFE+ + +I+ LP Sbjct: 164 ALRNGAEIIVATPGRLVDCIER-RLLVFSQCCYVIMDEADRMIDQGFEEPLTKILDALPV 222 Query: 219 ------NED-----------------RQSMLFSATQTTKVEDLARISLR-PGPLFINVVP 254 ED RQ+M+++AT VE +A+ LR P + I Sbjct: 223 SNEKPDTEDAENPQLMSRYLGGRDRYRQTMMYTATMPPTVEKIAKKYLRRPAIVTIGNAG 282 Query: 255 ETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQ-KKKIIVFLSSCNSVKYYAELLNYID 313 E ++ +E + DKR L L Q K IIVF++ + + A+ + Sbjct: 283 EAVDTVEQRVE---FIAGEDKRKRRLQEILNSGQFKPPIIVFVNIKRNCEMVAKDIKSWG 339 Query: 314 LPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDY 373 + LHG + Q++R + N + IL+ TD+A RG+D+P V ++ F+ P Y Sbjct: 340 FSTVTLHGSKTQEQREASLAALRNGQAHILVATDLAGRGIDVPDVSLVVNFNMPSTIEAY 399 Query: 374 IHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKA-------SKVP--LNEYEFPENK 421 HR+GRT R K G ++ FL + + LK SKVP L +E ++K Sbjct: 400 THRIGRTGRAGK-SGVAITFLGNEDADVMYDLKQIISKSSISKVPEELRRHEAAQSK 455 >4LJY-A nrPDB Length = 493 Score = 177 bits (449), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 116/387 (29%), Positives = 208/387 (53%), Gaps = 34/387 (8%) Query: 41 VEKFEELKLSQPTLKAI-EKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIP 99 V K+ +L LS T+ I EK+ F ++T +Q++ +P +++GRDV+G +KTGSGKT+++L+P Sbjct: 49 VTKWSQLGLSTDTMVLITEKLHFGSLTPIQSQALPAIMSGRDVIGISKTGSGKTISYLLP 108 Query: 100 AIELLHSLKFKPRNGTGI--IVITPTRELALQIFGVARELMEFHSQTFGIVI-GGANRRQ 156 + + + + ++ TG +++ PTRELALQI + E + + GG+ ++ Sbjct: 109 LLRQVKAQRPLSKHETGPMGLILAPTRELALQIHEEVTKFTEADTSIRSVCCTGGSEMKK 168 Query: 157 EAEKLMKGVNMLIATPGRLLDHLQNTKGFVF--KNLKALIIDEADRILEIGFEDEMRQII 214 + L +G +++ATPGR +D L G + K + +++DEADR+ ++GFE ++ QI+ Sbjct: 169 QITDLKRGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEADRLFDLGFEPQITQIM 228 Query: 215 KILPNEDRQSMLFSATQTTKVEDLA-RISLRPGPLFINVVPETDNSTADGLEQGYVVCDS 273 K + D+Q +LFSAT K+ A R+ P + IN + + ++Q + +C S Sbjct: 229 KTV-RPDKQCVLFSATFPNKLRSFAVRVLHSPISITIN----SKGMVNENVKQKFRICHS 283 Query: 274 -DKRFLLLFSFLKRNQK--------------------KKIIVFLSSCNSVKYYAELLNYI 312 D++F L + + K I+F+SS N + ++ L Sbjct: 284 EDEKFDNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNA 343 Query: 313 DLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRD 372 + +H + Q+R +F + IL+CT+V +RGL++P V +I ++ Sbjct: 344 GIVTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQ 403 Query: 373 YIHRVGRTARGTKGKGKSLMFLTPNEL 399 Y+H GRTARG++ G ++ L +EL Sbjct: 404 YVHTTGRTARGSRS-GTAITLLLHDEL 429 >5ANR-B nrPDB Length = 378 Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 118/345 (34%), Positives = 185/345 (53%), Gaps = 19/345 (5%) Query: 43 KFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE 102 +FE+ L + L I +MG+ + +Q +IP L+GRD+L AK G+GK+ A+LIP Sbjct: 6 EFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIP--- 62 Query: 103 LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFG-----IVIGGANRRQE 157 LL L K N + VI PTRELALQ+ + ++ S+ G GG N R + Sbjct: 63 LLERLDLKKDNIQAM-VIVPTRELALQVSQICIQV----SKHMGGAKVMATTGGTNLRDD 117 Query: 158 AEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKIL 217 +L V+++IATPGR+LD ++ V +++ +++DEAD++L F M II L Sbjct: 118 IMRLDDTVHVVIATPGRILDLIKKGVAKV-DHVQMIVLDEADKLLSQDFVQIMEDIILTL 176 Query: 218 PNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRF 277 P ++RQ +L+SAT V+ L+ P IN++ E T G+ Q Y ++ Sbjct: 177 P-KNRQILLYSATFPLSVQKFMNSHLQK-PYEINLMEEL---TLKGVTQYYAYVTERQKV 231 Query: 278 LLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCN 337 L + R Q + I+F +S V+ A+ ++ + +H K +Q+ R F +F N Sbjct: 232 HCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRN 291 Query: 338 AERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR 382 L+CTD+ RG+DI AV+ +I FD P Y+HR+GR+ R Sbjct: 292 GLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGR 336 >2Z0M-A nrPDB Length = 337 Score = 176 bits (445), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 122/348 (35%), Positives = 189/348 (54%), Gaps = 30/348 (8%) Query: 49 LSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLK 108 +++ +AI +MGF T VQ++TIP +L G++V+ AKTGSGKT A+ IP +EL Sbjct: 1 MNEKIEQAIREMGFKNFTEVQSKTIPLMLQGKNVVVRAKTGSGKTAAYAIPILEL----- 55 Query: 109 FKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNML 168 G +V+TPTREL Q+ R++ + V GG + + ++ + +++ Sbjct: 56 -----GMKSLVVTPTRELTRQVASHIRDIGRYMDTKVAEVYGGMPYKAQINRV-RNADIV 109 Query: 169 IATPGRLLDHLQNTKGFV-FKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLF 227 +ATPGRLLD +KG + + + +IIDEAD + E+GF D+++ I+ N + + LF Sbjct: 110 VATPGRLLDLW--SKGVIDLSSFEIVIIDEADLMFEMGFIDDIKIILAQTSNR-KITGLF 166 Query: 228 SATQTTKVEDLARISLRPGPLFINVVPETDNSTA-DGLEQGYVVCDSDKRFLLLFSFLKR 286 SAT ++ + + FI E + +E +V D R + L+ Sbjct: 167 SATIPEEIRKVVKD-------FITNYEEIEACIGLANVEHKFVHVKDDWRSKV--QALRE 217 Query: 287 NQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICT 346 N+ K +IVF+ + N V A+L+ D +EL G Q R F E +LI T Sbjct: 218 NKDKGVIVFVRTRNRV---AKLVRLFD-NAIELRGDLPQSVRNRNIDAFREGEYDMLITT 273 Query: 347 DVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFL 394 DVA+RGLDIP V+ +I FD P D R YIHR+GRT R + KG+++ F+ Sbjct: 274 DVASRGLDIPLVEKVINFDAPQDLRTYIHRIGRTGRMGR-KGEAITFI 320 >4KBG-A nrPDB Length = 365 Score = 172 bits (437), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 116/336 (34%), Positives = 179/336 (53%), Gaps = 16/336 (4%) Query: 43 KFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE 102 +F++ L L+A+ G TT T +QA +P L G+D++G A+TG+GKTLAF +P E Sbjct: 2 EFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAE 61 Query: 103 LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEF--HSQTFGIVIGGANRRQEAEK 160 L + + R + V+TPTRELALQ VA EL H + V GG ++ E Sbjct: 62 RLAPSQERGRKPRAL-VLTPTRELALQ---VASELTAVAPHLKVVA-VYGGTGYGKQKEA 116 Query: 161 LMKGVNMLIATPGRLLDHLQNTKGFV-FKNLKALIIDEADRILEIGFEDEMRQIIKILPN 219 L++G + ++ATPGR LD+L+ +G + ++ ++DEAD +L +GFE+E+ ++ P Sbjct: 117 LLRGADAVVATPGRALDYLR--QGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPP 174 Query: 220 EDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLL 279 RQ++LFSAT + + LA ++ P+ INV+ + + E+ V R + Sbjct: 175 -SRQTLLFSATLPSWAKRLAERYMK-NPVLINVIKDEPVT----YEEEAVPAPVRGRLEV 228 Query: 280 LFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAE 339 L L + +VF + + A+ L + P LHG Q +R F E Sbjct: 229 LSDLLYVASPDRAMVFTRTKAETEEIAQGLLRLGHPAQALHGDLSQGERERVLGAFRQGE 288 Query: 340 RGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIH 375 +L+ TDVAARGLDIP VD ++ + PD Y H Sbjct: 289 VRVLVATDVAARGLDIPQVDLVVHYRLPDRAEAYQH 324 >5ZWN-y nrPDB Length = 588 Score = 168 bits (425), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 123/390 (31%), Positives = 208/390 (53%), Gaps = 35/390 (8%) Query: 57 IEKMGFTTMTSVQARTIPPLL---AGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPR- 112 I+++ F + T +Q TIP + RD LG A TGSGKTLAF+IP L+ + PR Sbjct: 189 IQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPI--LIKMSRSPPRP 246 Query: 113 ------NGTGIIVITPTRELALQIFGVARELMEFHSQTFGI------VIGGANRRQEAEK 160 +G +++ PTREL QI +++ + S+ ++GG + + + Sbjct: 247 PSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLEEISFS 306 Query: 161 LMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQII-KILPN 219 L +G ++L+ATPGRL+D L+N V K ++ L++DEAD+++++GFED++ I+ K+ N Sbjct: 307 LSEGCDILVATPGRLIDSLEN-HLLVMKQVETLVLDEADKMIDLGFEDQVTNILTKVDIN 365 Query: 220 ED----RQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDK 275 D RQ+++F+AT T +E +A ++ P++ + ET + ++Q D+D+ Sbjct: 366 ADSAVNRQTLMFTATMTPVIEKIAAGYMQ-KPVYATIGVETGSEPL--IQQVVEYADNDE 422 Query: 276 RFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAE-LLNYIDLPVLELHGKQKQQKRTNTFFE 334 + II+F++ + + AE ++ V LHG + Q++R ++ Sbjct: 423 DKFKKLKPIVAKYDPPIIIFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQREHSLQL 482 Query: 335 FCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFL 394 F + I+I T+VAARGLDIP V ++ F DYIHR+GRT R +G ++ F+ Sbjct: 483 FRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDYIHRIGRTGRAA-NEGTAVSFV 541 Query: 395 TPNELGFL-----RYLKASKVPLNEYEFPE 419 + E L +Y++ PLN F E Sbjct: 542 SAAEDESLIRELYKYVRKHD-PLNSNIFSE 570 >2HYI-C nrPDB Length = 413 Score = 167 bits (423), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 117/404 (28%), Positives = 210/404 (51%), Gaps = 21/404 (5%) Query: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM 60 MAT + R R + + V E TS++ + P F+ + L + L+ I Sbjct: 7 MATSGSARKRLLKEEDMTKV-EFETSEEVDVTP---------TFDTMGLREDLLRGIYAY 56 Query: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 GF +++Q R I ++ GRDV+ +++G+GKT F +I +L L + R T +++ Sbjct: 57 GFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATF---SISVLQCLDIQVRE-TQALIL 112 Query: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 PTRELA+QI L ++ + IGG N ++ KL G +++ TPGR+ D ++ Sbjct: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172 Query: 181 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR 240 + + +K L++DEAD +L GF++++ + + LP Q +L SAT ++ ++ Sbjct: 173 R-RSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPAT-QVVLISATLPHEILEMTN 230 Query: 241 ISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDK-RFLLLFSFLKRNQKKKIIVFLSSC 299 P I ++ + D T +G++Q +V + ++ +F L + ++F ++ Sbjct: 231 -KFMTDP--IRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTK 287 Query: 300 NSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVD 359 V + E + + V +HG Q++R + EF + +LI TDV ARGLD+P V Sbjct: 288 RKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVS 347 Query: 360 WIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLR 403 II +D P++ YIHR+GR+ R + KG ++ F+ +++ LR Sbjct: 348 LIINYDLPNNRELYIHRIGRSGRYGR-KGVAINFVKNDDIRILR 390 >4W7S-A nrPDB Length = 463 Score = 167 bits (422), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 123/390 (31%), Positives = 208/390 (53%), Gaps = 35/390 (8%) Query: 57 IEKMGFTTMTSVQARTIPPLL---AGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPR- 112 I+++ F + T +Q TIP + RD LG A TGSGKTLAF+IP L+ + PR Sbjct: 64 IQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPI--LIKMSRSPPRP 121 Query: 113 ------NGTGIIVITPTRELALQIFGVARELMEFHSQTFGI------VIGGANRRQEAEK 160 +G +++ PTREL QI +++ + S+ ++GG + + + Sbjct: 122 PSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLEEISFS 181 Query: 161 LMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQII-KILPN 219 L +G ++L+ATPGRL+D L+N V K ++ L++DEAD+++++GFED++ I+ K+ N Sbjct: 182 LSEGCDILVATPGRLIDSLEN-HLLVMKQVETLVLDEADKMIDLGFEDQVTNILTKVDIN 240 Query: 220 ED----RQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDK 275 D RQ+++F+AT T +E +A ++ P++ + ET + ++Q D+D+ Sbjct: 241 ADSAVNRQTLMFTATMTPVIEKIAAGYMQ-KPVYATIGVETGSEPL--IQQVVEYADNDE 297 Query: 276 RFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAE-LLNYIDLPVLELHGKQKQQKRTNTFFE 334 + II+F++ + + AE ++ V LHG + Q++R ++ Sbjct: 298 DKFKKLKPIVAKYDPPIIIFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQREHSLQL 357 Query: 335 FCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFL 394 F + I+I T+VAARGLDIP V ++ F DYIHR+GRT R +G ++ F+ Sbjct: 358 FRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDYIHRIGRTGRAA-NEGTAVSFV 416 Query: 395 TPNELGFL-----RYLKASKVPLNEYEFPE 419 + E L +Y++ PLN F E Sbjct: 417 SAAEDESLIRELYKYVRKHD-PLNSNIFSE 445 >3EIQ-A nrPDB Length = 414 Score = 165 bits (417), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 107/346 (30%), Positives = 186/346 (53%), Gaps = 11/346 (3%) Query: 34 EGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKT 93 E V+ F+++ LS+ L+ I GF +++Q R I P + G DV+ A++G+GKT Sbjct: 32 ESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKT 91 Query: 94 LAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGAN 153 F AI +L ++ + T +V+ PTRELA QI V L ++ + IGG N Sbjct: 92 ATF---AISILQQIELDLK-ATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 147 Query: 154 RRQEAEKL-MKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQ 212 R E +KL M+ ++++ TPGR+ D L N + K +K ++DEAD +L GF+D++ Sbjct: 148 VRAEVQKLQMEAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYD 206 Query: 213 IIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCD 272 I + L N + Q +L SAT + V ++ + +R I ++ + + T +G+ Q Y+ + Sbjct: 207 IFQKL-NSNTQVVLLSATMPSDVLEVTKKFMRDP---IRILVKKEELTLEGIRQFYINVE 262 Query: 273 SDKRFL-LLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNT 331 ++ L L + + ++F+++ V + E ++ D V +HG Q++R Sbjct: 263 REEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVI 322 Query: 332 FFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRV 377 EF + +LI TD+ ARG+D+ V +I +D P + +YIHR+ Sbjct: 323 MREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 368 >1XTI-A nrPDB Length = 391 Score = 159 bits (402), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 111/351 (31%), Positives = 185/351 (52%), Gaps = 20/351 (5%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F + L L+AI GF + VQ IP + G DVL AK+G GKT F++ ++ Sbjct: 10 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 69 Query: 104 LHSLKFKPRNG-TGIIVITPTRELALQIFGVARELMEFHSQT----FGIVIGGANRRQEA 158 L +P G ++V+ TRELA QI ++E F + GG + +++ Sbjct: 70 L-----EPVTGQVSVLVMCHTRELAFQI---SKEYERFSKYMPNVKVAVFFGGLSIKKDE 121 Query: 159 EKLMKGV-NMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQIIKI 216 E L K ++++ TPGR+L L K K++K I+DE D++LE + ++++I ++ Sbjct: 122 EVLKKNCPHIVVGTPGRIL-ALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRM 180 Query: 217 LPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKR 276 P+E +Q M+FSAT + ++ + R P+ I V ET T GL+Q YV +++ Sbjct: 181 TPHE-KQVMMFSATLSKEIRPVCR-KFMQDPMEIFVDDET-KLTLHGLQQYYVKLKDNEK 237 Query: 277 FLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFC 336 LF L + ++++F+ S A+LL + P + +H Q++R + + +F Sbjct: 238 NRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFK 297 Query: 337 NAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR-GTKG 386 + +R IL+ T++ RG+DI V+ +D P+D Y+HRV R R GTKG Sbjct: 298 DFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKG 348 >3BER-A nrPDB Length = 249 Score = 155 bits (391), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 88/205 (42%), Positives = 134/205 (65%), Gaps = 13/205 (6%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F++L ++ +A +++G+T T +Q IP L GRD++G A+TGSGKT AF +P + Sbjct: 45 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALP---I 101 Query: 104 LHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGI----VIGGANRRQEAE 159 L++L P+ + V+TPTRELA QI E E + G+ ++GG + ++ Sbjct: 102 LNALLETPQRLFAL-VLTPTRELAFQI----SEQFEALGSSIGVQSAVIVGGIDSMSQSL 156 Query: 160 KLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPN 219 L K +++IATPGRL+DHL+NTKGF + LK L++DEADRIL + FE E+ +I+K++P Sbjct: 157 ALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPR 216 Query: 220 EDRQSMLFSATQTTKVEDLARISLR 244 DR++ LFSAT T KV+ L R +L+ Sbjct: 217 -DRKTFLFSATMTKKVQKLQRAALK 240 >5SUQ-A nrPDB Length = 446 Score = 151 bits (382), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 121/389 (31%), Positives = 191/389 (49%), Gaps = 24/389 (6%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F++ L +AI GF + VQ TIP + G DVL AK+G GKT F++ ++ Sbjct: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 Query: 104 LHSLKFKPRNG-TGIIVITPTRELALQIFGVARELMEFHSQT----FGIVIGGANRRQEA 158 L P G ++VI RELA QI E + F + GG ++A Sbjct: 124 L-----DPVPGEVAVVVICNARELAYQI---RNEYLRFSKYMPDVKTAVFYGGTPISKDA 175 Query: 159 EKLMK---GVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQII 214 E L ++++ATPGRL L K ++K +IDE D++LE + ++++I Sbjct: 176 ELLKNKDTAPHIVVATPGRL-KALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIF 234 Query: 215 KILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSD 274 + P D+Q M+FSAT + ++ + R L+ PL I V E T GL+Q Y+ + Sbjct: 235 RATPR-DKQVMMFSATLSQEIRPICRRFLQ-NPLEIFVDDEA-KLTLHGLQQYYIKLEER 291 Query: 275 KRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFE 334 ++ L L + ++I+F+ S +LLN + P + +HG KQ++R + Sbjct: 292 EKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKA 351 Query: 335 FCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR-GTKGKGKSLMF 393 F + E+ I + TDV RG+DI ++ I +D ++ Y+HRVGR R GTKG S + Sbjct: 352 FKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVS 411 Query: 394 LTPNELGFLRYLKASKVPLNEYEFPENKI 422 +E + + V + EFPE I Sbjct: 412 SKEDEEVLAKIQERFDVKIA--EFPEEGI 438 >5SUP-A nrPDB Length = 390 Score = 150 bits (379), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 121/389 (31%), Positives = 191/389 (49%), Gaps = 24/389 (6%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F++ L +AI GF + VQ TIP + G DVL AK+G GKT F++ ++ Sbjct: 8 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 67 Query: 104 LHSLKFKPRNG-TGIIVITPTRELALQIFGVARELMEFHSQT----FGIVIGGANRRQEA 158 L P G ++VI RELA QI E + F + GG ++A Sbjct: 68 L-----DPVPGEVAVVVICNARELAYQI---RNEYLRFSKYMPDVKTAVFYGGTPISKDA 119 Query: 159 EKLMK---GVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQII 214 E L ++++ATPGRL L K ++K +IDE D++LE + ++++I Sbjct: 120 ELLKNKDTAPHIVVATPGRL-KALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIF 178 Query: 215 KILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSD 274 + P D+Q M+FSAT + ++ + R L+ PL I V E T GL+Q Y+ + Sbjct: 179 RATPR-DKQVMMFSATLSQEIRPICRRFLQ-NPLEIFVDDEA-KLTLHGLQQYYIKLEER 235 Query: 275 KRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFE 334 ++ L L + ++I+F+ S +LLN + P + +HG KQ++R + Sbjct: 236 EKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKA 295 Query: 335 FCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR-GTKGKGKSLMF 393 F + E+ I + TDV RG+DI ++ I +D ++ Y+HRVGR R GTKG S + Sbjct: 296 FKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVS 355 Query: 394 LTPNELGFLRYLKASKVPLNEYEFPENKI 422 +E + + V + EFPE I Sbjct: 356 SKEDEEVLAKIQERFDVKIA--EFPEEGI 382 >2VSX-A nrPDB Length = 395 Score = 149 bits (375), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 113/371 (30%), Positives = 194/371 (52%), Gaps = 18/371 (4%) Query: 40 CVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIP 99 V KF++++L + L+ + GF +++Q R I P++ G DVL A++G+GKT F I Sbjct: 20 VVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIA 79 Query: 100 AIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAE 159 A++ + + P+ +++ PTRELALQI V L IGG + ++AE Sbjct: 80 ALQRIDTSVKAPQA----LMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAE 135 Query: 160 KLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPN 219 L + +++ TPGR+ D++Q + F +K I+DEAD +L GF++++ QI +LP Sbjct: 136 GL-RDAQIVVGTPGRVFDNIQRRR-FRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLP- 192 Query: 220 EDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYV-VCDSDKRFL 278 Q +L SAT V ++ +R P + ++ + D T +G++Q YV V + + ++ Sbjct: 193 PTTQVVLLSATMPNDVLEVTTKFMR-NP--VRILVKKDELTLEGIKQFYVNVEEEEYKYE 249 Query: 279 LLFSFLKRNQKKKIIVFLSSCNSVKYYAEL---LNYIDLPVLELHGKQKQQKRTNTFFEF 335 L + ++F CN+ + EL L V ++ QQ+R EF Sbjct: 250 CLTDLYDSISVTQAVIF---CNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEF 306 Query: 336 CNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLT 395 + ILI TD+ ARG+D+ V +I +D P + +YIHR+ KG ++ F+T Sbjct: 307 RSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRI-GRGGRFGRKGVAINFVT 365 Query: 396 PNELGFLRYLK 406 ++G +R L+ Sbjct: 366 NEDVGAMRELE 376 >5H1Y-A nrPDB Length = 281 Score = 137 bits (345), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 85/222 (38%), Positives = 130/222 (58%), Gaps = 13/222 (5%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 ++ F+E+K L+ ++K G T +Q + IP +L+GRD++G A TGSGKTL F +P Sbjct: 51 IKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPV 110 Query: 101 I----ELLHSLKFKPRNGTGIIVITPTRELALQIFGV----ARELMEFHSQTF--GIVIG 150 I E L F R G ++I P+RELA Q G+ R L E S + IG Sbjct: 111 IMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIG 170 Query: 151 GANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEM 210 G + +++ E + GV+M++ATPGRL+D LQ K + L +DEADR++++GFE ++ Sbjct: 171 GMSVKEQMETIRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFEGDI 229 Query: 211 RQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINV 252 R I + RQ++LFSAT K+++ A+ +L P+ INV Sbjct: 230 RTIFSYFKGQ-RQTLLFSATMPKKIQNFAKSALVK-PVTINV 269 >5GVS-A nrPDB Length = 231 Score = 136 bits (342), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 85/222 (38%), Positives = 130/222 (58%), Gaps = 13/222 (5%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 ++ F+E+K L+ ++K G T +Q + IP +L+GRD++G A TGSGKTL F +P Sbjct: 12 IKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPV 71 Query: 101 I----ELLHSLKFKPRNGTGIIVITPTRELALQIFGV----ARELMEFHSQTF--GIVIG 150 I E L F R G ++I P+RELA Q G+ R L E S + IG Sbjct: 72 IMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIG 131 Query: 151 GANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEM 210 G + +++ E + GV+M++ATPGRL+D LQ K + L +DEADR++++GFE ++ Sbjct: 132 GMSVKEQMETIRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFEGDI 190 Query: 211 RQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINV 252 R I + RQ++LFSAT K+++ A+ +L P+ INV Sbjct: 191 RTIFSYFKGQ-RQTLLFSATMPKKIQNFAKSALVK-PVTINV 230 >6B4I-E nrPDB Length = 430 Score = 135 bits (339), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 102/357 (28%), Positives = 181/357 (50%), Gaps = 21/357 (5%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLI 98 V+ FEEL+L L+ + MGF + +Q +P +LA ++++ +++G+GKT AF++ Sbjct: 42 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 101 Query: 99 PAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEA 158 + + P+ + ++PT ELALQ V ++ +F+ + N+ + Sbjct: 102 AMLSQVEPANKYPQ----CLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG 157 Query: 159 EKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEI-GFEDEMRQIIKIL 217 +K+ + + +I TPG +LD K K +K ++DEAD ++ G +D+ +I ++L Sbjct: 158 QKISEQI--VIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRML 215 Query: 218 PNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDS-DKR 276 P + Q +LFSAT V A+ + P P I + E + T D ++Q YV+C S D++ Sbjct: 216 P-RNCQMLLFSATFEDSVWKFAQ-KVVPDPNVIKLKREEE--TLDTIKQYYVLCSSRDEK 271 Query: 277 FLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFC 336 F L + + ++F + + + A L+ V L G+ ++R F Sbjct: 272 FQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFR 331 Query: 337 NAERGILICTDVAARGLDIPAVDWIIQFDPP------DDPRDYIHRVGRTAR-GTKG 386 + +L+ T+V ARG+D+ V +I FD P D Y+HR+GRT R G +G Sbjct: 332 EGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRG 388 >6AIC-A nrPDB Length = 214 Score = 134 bits (338), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 82/204 (40%), Positives = 124/204 (60%), Gaps = 14/204 (6%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 ++ F+EL +S T++++E MGF T +Q +IP L G D+LG A+TG+GKT AF IP Sbjct: 1 MQNFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPL 60 Query: 101 IELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGI----VIGGANRRQ 156 IE K + G +++ PTRELA+Q VA +L EF S+ G+ V GG + Sbjct: 61 IE-----KVVGKQGVQSLILAPTRELAMQ---VAEQLREF-SRGQGVQVVTVFGGMPIER 111 Query: 157 EAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKI 216 + + L KG +++ TPGR++DHL N + + LI+DEAD ++ +GF D+MR I+ Sbjct: 112 QIKALKKGPQIVVGTPGRVIDHL-NRRTLKTDGIHTLILDEADEMMNMGFIDDMRFIMDK 170 Query: 217 LPNEDRQSMLFSATQTTKVEDLAR 240 +P RQ+MLFSAT ++ L + Sbjct: 171 IPAVQRQTMLFSATMPKAIQALVQ 194 >3PEW-A nrPDB Length = 395 Score = 131 bits (329), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 113/403 (28%), Positives = 197/403 (48%), Gaps = 38/403 (9%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLIPAI 101 F+EL L+ LK I M F + +Q R +P LL R+++ +++G+GKT AF + + Sbjct: 7 FDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSLTML 66 Query: 102 ELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGA---NRRQEA 158 ++ P+ I + P+RELA Q V +E+ +F T +++ + N++ A Sbjct: 67 TRVNPEDASPQ----AICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDSFEKNKQINA 122 Query: 159 EKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRIL-EIGFEDEMRQIIKIL 217 + +++ TPG +LD L K + +K ++DEAD +L + G D+ ++ + L Sbjct: 123 Q-------VIVGTPGTVLD-LMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFL 174 Query: 218 PNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSD-KR 276 P +D Q +LFSAT V A+ + P + + +T+ D ++Q Y+ C ++ + Sbjct: 175 P-KDTQLVLFSATFADAVRQYAK-KIVPNANTLEL--QTNEVNVDAIKQLYMDCKNEADK 230 Query: 277 FLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFC 336 F +L I+F+++ + L V LHG + Q+R +F Sbjct: 231 FDVLTELYGVMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFR 290 Query: 337 NAERGILICTDVAARGLDIPAVDWIIQFDPPD------DPRDYIHRVGRTAR-GTKGKGK 389 +LI T+V ARG+DIP V ++ +D P DP YIHR+GRT R G KG Sbjct: 291 EGRSKVLITTNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAI 350 Query: 390 SLMFLTPNELGFL----RY---LKASKVPLNEYEFPENKIANV 425 S + N L +Y ++ ++VP ++++ E + V Sbjct: 351 SFVH-DKNSFNILSAIQKYFGDIEMTRVPTDDWDEVEKIVKKV 392 >3FE2-A nrPDB Length = 242 Score = 131 bits (329), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 79/201 (39%), Positives = 120/201 (59%), Gaps = 5/201 (2%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 V F E + I + FT T++QA+ P L+G D++G A+TGSGKTL++L+PA Sbjct: 28 VLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPA 87 Query: 101 IELLHSLKFKPR-NGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAE 159 I ++ F R +G +V+ PTRELA Q+ VA E + GGA + + Sbjct: 88 IVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIR 147 Query: 160 KLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQII-KILP 218 L +GV + IATPGRL+D L+ K + L++DEADR+L++GFE ++R+I+ +I P Sbjct: 148 DLERGVEICIATPGRLIDFLECGKTN-LRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRP 206 Query: 219 NEDRQSMLFSATQTTKVEDLA 239 DRQ++++SAT +V LA Sbjct: 207 --DRQTLMWSATWPKEVRQLA 225 >1WRB-A nrPDB Length = 253 Score = 127 bits (320), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 74/216 (34%), Positives = 125/216 (57%), Gaps = 9/216 (4%) Query: 32 APEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSG 91 P+ T +E F+ELKL I + T +Q IP +L RD++ A+TGSG Sbjct: 13 GPDYSATNVIENFDELKLDPTIRNNILLASYQRPTPIQKNAIPAILEHRDIMACAQTGSG 72 Query: 92 KTLAFLIPAI-----ELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFG 146 KT AFLIP I + L+ ++ +++ PTRELA+QI +++ Sbjct: 73 KTAAFLIPIINHLVCQDLNQQRYSKTAYPKCLILAPTRELAIQILSESQKFSLNTPLRSC 132 Query: 147 IVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGF 206 +V GGA+ + ++ G ++L+ATPGRL+D ++ K + K +++DEADR+L++GF Sbjct: 133 VVYGGADTHSQIREVQMGCHLLVATPGRLVDFIEKNK-ISLEFCKYIVLDEADRMLDMGF 191 Query: 207 EDEMRQIIK--ILPNE-DRQSMLFSATQTTKVEDLA 239 E ++R+II+ +P+ +RQ+++FSAT +++ LA Sbjct: 192 EPQIRKIIEESNMPSGINRQTLMFSATFPKEIQKLA 227 >4PX9-A nrPDB Length = 292 Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 83/230 (36%), Positives = 130/230 (56%), Gaps = 26/230 (11%) Query: 29 NNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKT 88 NN P +E F ++++ + + IE +T T VQ IP + RD++ A+T Sbjct: 58 NNCPPH------IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQT 111 Query: 89 GSGKTLAFLIPAI---------ELLHSLKFKPRNGTG-----IIVITPTRELALQIFGVA 134 GSGKT AFL+P + E L ++K R G +V+ PTRELA+QI+ A Sbjct: 112 GSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEA 171 Query: 135 RELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTK-GFVFKNLKAL 193 R+ +V GGA+ Q+ L +G ++L+ATPGRL+D ++ K G F K L Sbjct: 172 RKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDF--CKYL 229 Query: 194 IIDEADRILEIGFEDEMRQIIK---ILPNEDRQSMLFSATQTTKVEDLAR 240 ++DEADR+L++GFE ++R+I++ + P R +M+FSAT +++ LAR Sbjct: 230 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLAR 279 >2GXQ-A nrPDB Length = 207 Score = 125 bits (314), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 81/214 (37%), Positives = 128/214 (59%), Gaps = 12/214 (5%) Query: 43 KFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE 102 +F++ L L+A+ G TT T +QA +P L G+D++G A+TG+GKTLAF +P E Sbjct: 2 EFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAE 61 Query: 103 LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEF--HSQTFGIVIGGANRRQEAEK 160 L + + R +V+TPTRELALQ VA EL H + V GG ++ E Sbjct: 62 RLAPSQERGRKPRA-LVLTPTRELALQ---VASELTAVAPHLKVVA-VYGGTGYGKQKEA 116 Query: 161 LMKGVNMLIATPGRLLDHLQNTKGFV-FKNLKALIIDEADRILEIGFEDEMRQIIKILPN 219 L++G + ++ATPGR LD+L+ +G + ++ ++DEAD +L +GFE+E+ ++ P Sbjct: 117 LLRGADAVVATPGRALDYLR--QGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPP 174 Query: 220 EDRQSMLFSATQTTKVEDLARISLRPGPLFINVV 253 RQ++LFSAT + + LA ++ P+ INV+ Sbjct: 175 -SRQTLLFSATLPSWAKRLAERYMK-NPVLINVI 206 >5GJU-A nrPDB Length = 205 Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 76/201 (37%), Positives = 113/201 (56%), Gaps = 13/201 (6%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F +L L P L+A+ +G+ + +QA IP LL GRDVLG A+TGSGKT AF +P ++ Sbjct: 3 FADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQN 62 Query: 104 LHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVI----GGANRRQEAE 159 L P+ I+V+ PTRELA+Q VA + +F G+ + GG + Sbjct: 63 LDPELKAPQ----ILVLAPTRELAVQ---VAEAMTDFSKHMRGVNVVALYGGQRYDVQLR 115 Query: 160 KLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPN 219 L +G +++ TPGRLLDHL+ L L++DEAD +L +GF +++ I+ +P Sbjct: 116 ALRQGPQIVVGTPGRLLDHLKRGT-LDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIP- 173 Query: 220 EDRQSMLFSATQTTKVEDLAR 240 E Q+ LFSAT + + R Sbjct: 174 EGHQTALFSATMPEAIRRITR 194 >3IUY-A nrPDB Length = 228 Score = 122 bits (305), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 78/204 (38%), Positives = 125/204 (61%), Gaps = 12/204 (5%) Query: 54 LKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHS--LKFKP 111 LK+I ++G T +Q++ P +L G D++ A+TG+GKTL++L+P L S + + Sbjct: 32 LKSIIRVGILKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISREQ 91 Query: 112 RNGTGIIVITPTRELALQIFGVARELMEFHSQTFG--IVIGGANRRQEAEKLMKGVNMLI 169 RNG G++V+TPTRELAL V E ++ + + GG NR + E + KGV+++I Sbjct: 92 RNGPGMLVLTPTRELALH---VEAECSKYSYKGLKSICIYGGRNRNGQIEDISKGVDIII 148 Query: 170 ATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQI-IKILPNEDRQSMLFS 228 ATPGRL D LQ +++ L+IDEAD++L++ FE ++R+I + + P DRQ+++ S Sbjct: 149 ATPGRLND-LQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRP--DRQTVMTS 205 Query: 229 ATQTTKVEDLARISLRPGPLFINV 252 AT V LA +S P+ + V Sbjct: 206 ATWPDTVRQLA-LSYLKDPMIVYV 228 >5ZBZ-A nrPDB Length = 220 Score = 117 bits (294), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 73/212 (34%), Positives = 119/212 (56%), Gaps = 7/212 (3%) Query: 34 EGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKT 93 E V+ F+++ LS+ L+ I GF +++Q R I P + G DV+ A++G+GKT Sbjct: 6 ESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKT 65 Query: 94 LAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGAN 153 F AI +L ++ + T +V+ PTRELA QI V L ++ + IGG N Sbjct: 66 ATF---AISILQQIELDLK-ATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 121 Query: 154 RRQEAEKL-MKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQ 212 R E +KL M+ ++++ TPGR+ D L N + K +K ++DEAD +L GF+D++ Sbjct: 122 VRAEVQKLQMEAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYD 180 Query: 213 IIKILPNEDRQSMLFSATQTTKVEDLARISLR 244 I + L N + Q +L SAT + V ++ + +R Sbjct: 181 IFQKL-NSNTQVVLLSATMPSDVLEVTKKFMR 211 >3FHO-A nrPDB Length = 508 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 104/383 (27%), Positives = 190/383 (49%), Gaps = 49/383 (12%) Query: 68 VQARTIPPLLAG--RDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRE 125 +Q + +P LL+ R+++G +++G+GKT AF + + + + KP+ I + P+RE Sbjct: 145 IQEKALPLLLSNPPRNMIGQSQSGTGKTAAFALTMLSRVDASVPKPQ----AICLAPSRE 200 Query: 126 LALQIFGVARELMEFHS--QTFGIVIGGANRRQEAEKLMKGV----NMLIATPGRLLDHL 179 LA QI V E+ ++ FGI + + KG ++I TPG ++D L Sbjct: 201 LARQIMDVVTEMGKYTEVKTAFGI----------KDSVPKGAKIDAQIVIGTPGTVMD-L 249 Query: 180 QNTKGFVFKNLKALIIDEADRIL-EIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDL 238 + +++K ++DEAD +L + G D+ +I +LP + Q +LFSAT + +VE Sbjct: 250 MKRRQLDARDIKVFVLDEADNMLDQQGLGDQSMRIKHLLP-RNTQIVLFSATFSERVEKY 308 Query: 239 ARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKR----FLLLFSFLKRNQKKKIIV 294 A R P + +T+ + +G++Q Y+ C S++ + L+ L Q I+ Sbjct: 309 AE---RFAPNANEIRLKTEELSVEGIKQLYMDCQSEEHKYNVLVELYGLLTIGQS---II 362 Query: 295 FLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLD 354 F ++ + A + V L G + +R F +L+ T+V ARG+D Sbjct: 363 FCKKKDTAEEIARRMTADGHTVACLTGNLEGAQRDAIMDSFRVGTSKVLVTTNVIARGID 422 Query: 355 IPAVDWIIQFDPP------DDPRDYIHRVGRTARGTKGKGKSLMFL----TPNELGFLR- 403 + V+ ++ +D P DP+ Y+HR+GRT R + G S+ F+ + E+ ++ Sbjct: 423 VSQVNLVVNYDMPLDQAGRPDPQTYLHRIGRTGRFGR-VGVSINFVHDKKSWEEMNAIQE 481 Query: 404 YLK--ASKVPLNEYEFPENKIAN 424 Y + ++VP ++YE E + N Sbjct: 482 YFQRPITRVPTDDYEELEKVVKN 504 >3BOR-A nrPDB Length = 237 Score = 114 bits (285), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 74/212 (34%), Positives = 118/212 (55%), Gaps = 7/212 (3%) Query: 34 EGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKT 93 E V+ F+++ L + L+ I GF +++Q R I P + G DV+ A++G+GKT Sbjct: 22 ESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKT 81 Query: 94 LAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGAN 153 F AI +L L+ + + T +V+ PTRELA QI V L ++ T IGG N Sbjct: 82 ATF---AISILQQLEIEFKE-TQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTN 137 Query: 154 RRQEAEKLM-KGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQ 212 R E +KL + ++++ TPGR+ D L N + K +K ++DEAD +L GF+D++ + Sbjct: 138 VRNEMQKLQAEAPHIVVGTPGRVFDML-NRRYLSPKWIKMFVLDEADEMLSRGFKDQIYE 196 Query: 213 IIKILPNEDRQSMLFSATQTTKVEDLARISLR 244 I + L N Q +L SAT T V ++ + +R Sbjct: 197 IFQKL-NTSIQVVLLSATMPTDVLEVTKKFMR 227 >1VEC-A nrPDB Length = 206 Score = 107 bits (267), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 72/190 (37%), Positives = 111/190 (58%), Gaps = 9/190 (4%) Query: 43 KFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE 102 +FE+ L + L I +MG+ + +Q +IP L+GRD+L AK G+GK+ A+LIP Sbjct: 4 EFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIP--- 60 Query: 103 LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELME-FHSQTFGIVIGGANRRQEAEKL 161 LL L K N +VI PTRELALQ+ + ++ + GG N R + +L Sbjct: 61 LLERLDLKKDNIQA-MVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRL 119 Query: 162 MKGVNMLIATPGRLLDHLQNTKGFV-FKNLKALIIDEADRILEIGFEDEMRQIIKILPNE 220 V+++IATPGR+LD ++ KG +++ +++DEAD++L F M II LP + Sbjct: 120 DDTVHVVIATPGRILDLIK--KGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLP-K 176 Query: 221 DRQSMLFSAT 230 +RQ +L+SAT Sbjct: 177 NRQILLYSAT 186 >1QVA-A nrPDB Length = 223 Score = 105 bits (262), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 67/196 (34%), Positives = 110/196 (56%), Gaps = 7/196 (3%) Query: 40 CVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIP 99 V KF++++L + L+ + GF +++Q R I P++ G DVL A++G+GKT F I Sbjct: 19 VVYKFDDMELDEQLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIA 78 Query: 100 AIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAE 159 A++ + + P+ +++ PTRELALQI V L IGG + ++AE Sbjct: 79 ALQRIDTSVKAPQA----LMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAE 134 Query: 160 KLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPN 219 L + +++ TPGR+ D++Q + F +K I+DEAD +L GF++++ QI +LP Sbjct: 135 GL-RDAQIVVGTPGRVFDNIQRRR-FRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLP- 191 Query: 220 EDRQSMLFSATQTTKV 235 Q +L SAT V Sbjct: 192 PTTQVVLLSATMPNDV 207 >1Q0U-A nrPDB Length = 219 Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 70/205 (34%), Positives = 117/205 (57%), Gaps = 13/205 (6%) Query: 54 LKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRN 113 ++AI+ + F T +Q R IP L G ++G ++TG+GKT A+L+P +E K KP Sbjct: 16 IEAIKTLRFYKPTEIQERIIPGALRGESMVGQSQTGTGKTHAYLLPIME-----KIKPER 70 Query: 114 GTGIIVIT-PTRELALQIFGVARELMEFHSQTFGIV----IGGANRRQEAEKLMKGVNML 168 VIT PTRELA QI+ ++ +F + IV IGG ++++ EKL +++ Sbjct: 71 AEVQAVITAPTRELATQIYHETLKITKFCPKDRMIVARCLIGGTDKQKALEKLNVQPHIV 130 Query: 169 IATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFS 228 I TPGR+ D ++ + L++DEAD +L++GF ++ QI +P +D Q ++FS Sbjct: 131 IGTPGRINDFIRE-QALDVHTAHILVVDEADLMLDMGFITDVDQIAARMP-KDLQMLVFS 188 Query: 229 ATQTTKVEDLARISLRPGPLFINVV 253 AT K++ + + P F++V+ Sbjct: 189 ATIPEKLKPFLKKYME-NPTFVHVL 212 >3DKP-A nrPDB Length = 245 Score = 98.2 bits (243), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 72/208 (34%), Positives = 112/208 (53%), Gaps = 16/208 (7%) Query: 45 EELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELL 104 +E K++ L+ I GF T +Q + IP +L GR++L +A TGSGKTLAF IP +L Sbjct: 32 QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP---IL 88 Query: 105 HSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLM-- 162 LK G ++I+PTRELA QI REL++ S+ G I ++ A K Sbjct: 89 MQLKQPANKGFRALIISPTRELASQIH---RELIKI-SEGTGFRIHMIHKAAVAAKKFGP 144 Query: 163 ---KGVNMLIATPGRLLDHL-QNTKGFVFKNLKALIIDEADRILE---IGFEDEMRQIIK 215 K ++L+ TP RL+ L Q+ G +++ L++DE+D++ E GF D++ I Sbjct: 145 KSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFL 204 Query: 216 ILPNEDRQSMLFSATQTTKVEDLARISL 243 + + +FSAT VE +++L Sbjct: 205 ACTSHKVRRAMFSATFAYDVEQWCKLNL 232 >1T6N-A nrPDB Length = 220 Score = 94.0 bits (232), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 66/215 (30%), Positives = 115/215 (53%), Gaps = 18/215 (8%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F + L L+AI GF + VQ IP + G DVL AK+G GKT F++ ++ Sbjct: 16 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQ- 74 Query: 104 LHSLKFKPRNG-TGIIVITPTRELALQIFGVARELMEFHSQT----FGIVIGGANRRQEA 158 + +P G ++V+ TRELA QI ++E F + GG + +++ Sbjct: 75 ----QLEPVTGQVSVLVMCHTRELAFQI---SKEYERFSKYMPNVKVAVFFGGLSIKKDE 127 Query: 159 EKLMKGV-NMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQIIKI 216 E L K ++++ TPGR+L L K K++K I+DE D++LE + ++++I ++ Sbjct: 128 EVLKKNCPHIVVGTPGRILA-LARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRM 186 Query: 217 LPNEDRQSMLFSATQTTKVEDLARISLR-PGPLFI 250 P+E +Q M+FSAT + ++ + R ++ P +F+ Sbjct: 187 TPHE-KQVMMFSATLSKEIRPVCRKFMQDPMEIFV 220 >2OXC-A nrPDB Length = 230 Score = 83.6 bits (205), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 66/201 (32%), Positives = 107/201 (53%), Gaps = 33/201 (16%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE- 102 FE L LS+P L+ + GF + VQ + IP G D++ AK+G+GKT F A++ Sbjct: 26 FESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDS 85 Query: 103 -LLHSLKFKPRNGTGIIVITPTRELALQI------FGVARELMEFHSQTFGIVIGGANRR 155 +L +L T I+++ PTRE+A+QI G+ E +E H + IGG Sbjct: 86 LVLENLS------TQILILAPTREIAVQIHSVITAIGIKMEGLECH-----VFIGGTPLS 134 Query: 156 QEAEKLMKGVNMLIATPGRL-----LDHLQNTKGFVFKNLKALIIDEADRILEIG-FEDE 209 Q+ +L K ++ + +PGR+ LD+L +++ I+DEAD++LE G F+++ Sbjct: 135 QDKTRL-KKCHIAVGSPGRIKQLIELDYLNP------GSIRLFILDEADKLLEEGSFQEQ 187 Query: 210 MRQIIKILPNEDRQSMLFSAT 230 + I LP +Q + SAT Sbjct: 188 INWIYSSLP-ASKQMLAVSAT 207 >3FHC-B nrPDB Length = 235 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 58/203 (28%), Positives = 108/203 (53%), Gaps = 10/203 (4%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLA--GRDVLGAAKTGSGKTLAFLI 98 V+ FEEL+L L+ + MGF + +Q +P +LA ++++ +++G+GKT AF++ Sbjct: 24 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 83 Query: 99 PAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEA 158 + + P+ + ++PT ELALQ V ++ +F+ + N+ + Sbjct: 84 AMLSQVEPANKYPQ----CLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG 139 Query: 159 EKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEI-GFEDEMRQIIKIL 217 +K+ + + +I TPG +LD K K +K ++DEAD ++ G +D+ +I ++L Sbjct: 140 QKISEQI--VIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRML 197 Query: 218 PNEDRQSMLFSATQTTKVEDLAR 240 P + Q +LFSAT V A+ Sbjct: 198 P-RNCQMLLFSATFEDSVWKFAQ 219 >3FMO-B nrPDB Length = 300 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 61/215 (28%), Positives = 113/215 (52%), Gaps = 11/215 (5%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLI 98 V+ FEEL+L L+ + MGF + +Q +P +LA ++++ +++G+GKT AF++ Sbjct: 91 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 150 Query: 99 PAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEA 158 + + P+ + ++PT ELALQ V ++ +F+ + N+ + Sbjct: 151 AMLSQVEPANKYPQ----CLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG 206 Query: 159 EKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEI-GFEDEMRQIIKIL 217 +K+ + + +I TPG +LD K K +K ++DEAD ++ G +D+ +I ++L Sbjct: 207 QKISEQI--VIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRML 264 Query: 218 PNEDRQSMLFSATQTTKVEDLARISLRPGPLFINV 252 P + Q +LFSAT V A+ + P P I + Sbjct: 265 P-RNCQMLLFSATFEDSVWKFAQ-KVVPDPNVIKL 297 >2KBE-A nrPDB Length = 226 Score = 78.6 bits (192), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 61/202 (30%), Positives = 106/202 (52%), Gaps = 17/202 (8%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLIPAI 101 F+EL L+ LK I M F + +Q R +P LL R+++ +++G+GKT AF + + Sbjct: 24 FDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSLTML 83 Query: 102 ELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKL 161 ++ P+ I + P+RELA Q V +E+ +F T +++ + + Sbjct: 84 TRVNPEDASPQ----AICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDSFEKN----- 134 Query: 162 MKGVN--MLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRIL-EIGFEDEMRQIIKILP 218 K +N +++ TPG +LD L K + +K ++DEAD +L + G D+ ++ + LP Sbjct: 135 -KQINAQVIVGTPGTVLD-LMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLP 192 Query: 219 NEDRQSMLFSATQTTKVEDLAR 240 +D Q +LFSAT V A+ Sbjct: 193 -KDTQLVLFSATFADAVRQYAK 213 >6CRM-A nrPDB Length = 541 Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 97/427 (22%), Positives = 177/427 (41%), Gaps = 54/427 (12%) Query: 33 PEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGK 92 P G E + + L++ L+ E G+ QA I +L GRD L TG GK Sbjct: 16 PRGSHMAQAEVYSQETLAKQVLQ--ETFGYQQFRPGQATIIDAVLEGRDCLVVMPTGGGK 73 Query: 93 TLAFLIPAIELLHSLKFKPRNGTGIIV---ITPTRELALQIF--GVARELMEFHSQTFGI 147 +L + IPA+ + G I+V I+ ++ Q+ GVA Sbjct: 74 SLCYQIPAL---------VKTGLTIVVSPLISLMKDQVDQLLANGVA-----------AA 113 Query: 148 VIGGANRRQEAEKLMKG-----VNMLIATPGRLL-DHLQNTKGFVFKNLKALIIDEADRI 201 + R+E + ++ G V +L P RL+ D+ +T G+ +L + +DEA I Sbjct: 114 CLNSTQSREEQQAVLAGCRTGQVRLLYIAPERLMMDNFIDTLGY--WDLAMVAVDEAHCI 171 Query: 202 LEIG--FEDE---MRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPET 256 + G F E + Q+ P ++ +A TT+ D+ R+ PL Sbjct: 172 SQWGHDFRPEYAALGQLRARFPAVPFMALTATADDTTR-RDIVRLLGLDDPLI------- 223 Query: 257 DNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPV 316 + S+ D Y++ + K L +++ + K I++ +S V+ A L + Sbjct: 224 EISSFDRPNIRYMLMEKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSRGISA 283 Query: 317 LELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHR 376 H + + R + +F + I++ T G++ P V +++ FD P + Y Sbjct: 284 AAYHAGLEHEVRASVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQE 343 Query: 377 VGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPENKI----ANVQSQ-LEK 431 GR R ++++F P ++ +LR K P + +K+ A ++Q + Sbjct: 344 TGRAGRDGL-PAEAMLFYDPADMAWLRRCLEEKAPGPLQDIERHKLNAMGAFAEAQTCRR 402 Query: 432 LIKSNYY 438 L+ NY+ Sbjct: 403 LVLLNYF 409 >1OYY-A nrPDB Length = 523 Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 88/370 (23%), Positives = 152/370 (41%), Gaps = 63/370 (17%) Query: 58 EKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGI 117 E G+ Q I +L+GRD L TG GK+L + IPA+ LL+ L Sbjct: 19 ETFGYQQFRPGQEEIIDTVLSGRDCLVVMPTGGGKSLCYQIPAL-LLNGLT--------- 68 Query: 118 IVITPTRELA------LQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKG-----VN 166 +V++P L LQ GVA + +QT R++ ++M G + Sbjct: 69 VVVSPLISLMKDQVDQLQANGVAAACLN-STQT----------REQQLEVMTGCRTGQIR 117 Query: 167 MLIATPGRL-----LDHLQNTKGFVFKNLKALIIDEADRILEIGFE--------DEMRQI 213 +L P RL L+HL + N L +DEA I + G + ++RQ Sbjct: 118 LLYIAPERLMLDNFLEHLAHW------NPVLLAVDEAHCISQWGHDFRPEYAALGQLRQR 171 Query: 214 IKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDS 273 LP ++ +A TT+ +D+ R+ PL S+ D Y++ + Sbjct: 172 FPTLPF---MALTATADDTTR-QDIVRLLGLNDPLI-------QISSFDRPNIRYMLMEK 220 Query: 274 DKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFF 333 K L +++ + K I++ +S V+ A L + H + R + Sbjct: 221 FKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQE 280 Query: 334 EFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMF 393 +F + I++ T G++ P V +++ FD P + Y GR R ++++F Sbjct: 281 KFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGL-PAEAMLF 339 Query: 394 LTPNELGFLR 403 P ++ +LR Sbjct: 340 YDPADMAWLR 349 >4Q48-A nrPDB Length = 525 Score = 65.1 bits (157), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 86/360 (23%), Positives = 145/360 (40%), Gaps = 29/360 (8%) Query: 60 MGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIV 119 G+ VQ + + G + L TG GK+L + +P++ R GTGI+V Sbjct: 20 WGYPAFRGVQGEIVQQVAEGGNALVLMPTGGGKSLCYQLPSLL---------RPGTGIVV 70 Query: 120 ITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKG-VNMLIATPGRLLDH 178 +P L R+ + + R+ + L++G +++L P RLL Sbjct: 71 -SPLIALMKDQVDTLRQ-NGVRAAFLNSTLLPHEAREVEDALLRGDLDLLYVAPERLL-- 126 Query: 179 LQNTKGFVFKNLKALI-IDEADRILEIG--FEDEMRQIIKI---LPNEDRQSMLFSATQT 232 + T + + AL IDEA + + G F E +Q+ + P R ++ +A + Sbjct: 127 MPRTLDLLERAPVALFAIDEAHCVSQWGHDFRPEYQQLSVLAERFPELPRVALTATADER 186 Query: 233 TKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKI 292 T+ + + + L P F++ + GL+ DS K LL F + + Sbjct: 187 TRADIKSVLRLEDAPQFVSSFDRPNIQYRVGLK------DSPKTQLLHF-IREEHPGDAG 239 Query: 293 IVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVA-AR 351 IV+ S SV+ A+ L + L H +R N F N E G+++C VA Sbjct: 240 IVYCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLN-EEGVIVCATVAFGM 298 Query: 352 GLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVP 411 G+D P V ++ D P Y GR R +++ + + R L S P Sbjct: 299 GIDKPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTAWMVYGLSDVVNVRRMLAQSDAP 358 >5V9X-A nrPDB Length = 877 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 42/150 (28%), Positives = 66/150 (44%), Gaps = 14/150 (9%) Query: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 F T QA + G + L A TGSGKTLA + AI+ L +P GT ++ + Sbjct: 44 AFAAPTPAQADAWSAISEGNNTLVIAPTGSGKTLAAFLWAIDRLADPAREPSQGTQVLYV 103 Query: 121 TPTRELALQI--------FGVARELMEFH-----SQTFGIVIGGANRRQEAEKLMKGVNM 167 +P + LA+ + G+ R + E H S T G+ G Q + ++ Sbjct: 104 SPLKALAVDVERNLRTPLTGITR-VAERHGLPAPSITVGVRSGDTPPNQRRAMIANPPDV 162 Query: 168 LIATPGRLLDHLQNTKGFVFKNLKALIIDE 197 LI TP L L + +++ +I+DE Sbjct: 163 LITTPESLFLMLTSAARETLTSVRTVIVDE 192 Score = 31.6 bits (70), Expect = 0.83, Method: Compositional matrix adjust. Identities = 17/74 (22%), Positives = 32/74 (43%) Query: 320 HGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGR 379 HG +++R + + ++ T G+D+ AVD +IQ + P + RVGR Sbjct: 356 HGSVSKEQRAQVEDDLKSGRLRAVVATSSLELGIDMGAVDLVIQVEAPPSVASGLQRVGR 415 Query: 380 TARGTKGKGKSLMF 393 + ++F Sbjct: 416 AGHQVGEISQGVLF 429 >1WP9-A nrPDB Length = 494 Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 8/117 (6%) Query: 284 LKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQK--------QQKRTNTFFEF 335 L+R Q KIIVF + + K L + G+ Q+++ EF Sbjct: 356 LQRKQNSKIIVFTNYRETAKKIVNELVKDGIKAKRFVGQASKENDRGLSQREQKLILDEF 415 Query: 336 CNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLM 392 E +L+ T V GLD+P VD ++ ++P I R GRT R G+ LM Sbjct: 416 ARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSIQRRGRTGRHMPGRVIILM 472 >5LST-A nrPDB Length = 693 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 78/367 (21%), Positives = 133/367 (36%), Gaps = 36/367 (9%) Query: 53 TLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPR 112 +A+E++G Q R + +L+G L TG+GK+L + +PA L + R Sbjct: 46 VFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPA------LLYSRR 99 Query: 113 NGTGIIVITPTRELA-LQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMK----GVNM 167 + +V++P L Q+ G+ L + G R+Q L K V++ Sbjct: 100 SPCLTLVVSPLLSLMDDQVSGLPPCL------KAACIHSGMTRKQRESVLQKIRAAQVHV 153 Query: 168 LIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIG--FEDEMRQIIKILPNEDRQSM 225 L+ TP L+ + IDEA + + F ++ K+L E Sbjct: 154 LMLTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVL-RERMGVH 212 Query: 226 LF-----SATQTTKVEDLARISLRPGPLFINVVPETDN-----STADGLEQGYVVCDSDK 275 F +AT+ T + +++ P P N S +Q + K Sbjct: 213 CFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGK 272 Query: 276 RFLLLFSFL----KRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLE-LHGKQKQQKRTN 330 RF L S + +R ++I L +C + E H ++R Sbjct: 273 RFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRR 332 Query: 331 TFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKS 390 F + +++ T GLD P V ++ P Y+ VGR R + Sbjct: 333 VQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQ-PAHC 391 Query: 391 LMFLTPN 397 +FL P Sbjct: 392 HLFLQPQ 398 >1GM5-A nrPDB Length = 780 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 77/337 (22%), Positives = 140/337 (41%), Gaps = 60/337 (17%) Query: 88 TGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGI 147 GSGKT+ + ++ + G + PT LA+Q + R +E S+ F I Sbjct: 398 VGSGKTVVAQLAILDNYEA-------GFQTAFMVPTSILAIQHY---RRTVESFSK-FNI 446 Query: 148 VIG---GANRRQEAEKLMKG-----VNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEAD 199 + GA E EK+ G ++++I T + + + FKNL +IIDE Sbjct: 447 HVALLIGATTPSEKEKIKSGLRNGQIDVVIGTHALIQEDVH------FKNLGLVIIDEQH 500 Query: 200 RILEIGFEDEMRQIIKILPNEDRQ--SMLFSATQTTKVEDLARISLRPGPLFINVVPETD 257 R F + R+ L N+ + +++ SAT + LA G L + V+ E Sbjct: 501 R-----FGVKQREA---LMNKGKMVDTLVMSATPIPRSMALAFY----GDLDVTVIDEM- 547 Query: 258 NSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFL-------SSCNSVKYYAELLN 310 G ++ + R ++ F+++ + F+ S +VK E+ Sbjct: 548 ---PPGRKEVQTMLVPMDRVNEVYEFVRQEVMRGGQAFIVYPLIEESDKLNVKSAVEMYE 604 Query: 311 YIDLPVLE------LHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQF 364 Y+ V +HG+ Q+++ EF IL+ T V G+D+P + ++ Sbjct: 605 YLSKEVFPEFKLGLMHGRLSQEEKDRVMLEFAEGRYDILVSTTVIEVGIDVPRANVMVIE 664 Query: 365 DPPDDPRDYIHRV-GRTARGTKGKGKSLMFLTPNELG 400 +P +H++ GR RG + ++ FL ++G Sbjct: 665 NPERFGLAQLHQLRGRVGRGGQ---EAYCFLVVGDVG 698 >2FWR-A nrPDB Length = 472 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/125 (22%), Positives = 59/125 (47%), Gaps = 5/125 (4%) Query: 269 VVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKR 328 + +S + L L+R++K KII+F + N + Y + +P + + +++R Sbjct: 329 IAFNSKNKIRKLREILERHRKDKIIIF-TRHNELVY--RISKVFLIPAIT--HRTSREER 383 Query: 329 TNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKG 388 F ++ + V G+D+P + + R+YI R+GR R +KGK Sbjct: 384 EEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREYIQRLGRILRPSKGKK 443 Query: 389 KSLMF 393 +++++ Sbjct: 444 EAVLY 448 >5X0Y-O nrPDB Length = 735 Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust. Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 6/112 (5%) Query: 291 KIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAA 350 ++++F + + L YI++ L L G K +R+ NA +C ++ Sbjct: 440 RVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSE-LLRLFNAPDSEYLCFILST 498 Query: 351 R----GLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR-GTKGKGKSLMFLTPN 397 R GL++ D +I FD +P + R R G K + + L +T N Sbjct: 499 RAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTN 550 >4CDG-A nrPDB Length = 673 Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust. Identities = 91/396 (22%), Positives = 146/396 (36%), Gaps = 65/396 (16%) Query: 42 EKFEELKLSQPTLKAI-----EKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAF 96 E+F+ L S P K + +K G + Q I L G D TG GK+L + Sbjct: 9 ERFQSL--SFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCY 66 Query: 97 LIPAIELLHSLKFKPRNGTGI-IVITPTRELALQIFGVARELMEFHSQTF-GIVIGGANR 154 +PA G+ +VI+P R L + ++ + S + G Sbjct: 67 QLPACV-----------SPGVTVVISPLRSL------IVDQVQKLTSLDIPATYLTGDKT 109 Query: 155 RQEAEKLMKG-------VNMLIATP------GRLLDHLQNTKGFVFKNLKALIIDEADRI 201 EA + + +L TP RL+ L+N + K L +IDEA + Sbjct: 110 DSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENL--YERKLLARFVIDEAHCV 167 Query: 202 LEIGFEDEMRQIIKILPNEDRQS------MLFSATQTTKVED--LARIS-LRPGPLFINV 252 + G + RQ K + N RQ M +AT +V+ L ++ LRP ++ Sbjct: 168 SQWGH--DFRQDYKRM-NMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSF 224 Query: 253 VPETDNSTADGLEQGYVVCDSDKR--FLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLN 310 + YV+ K+ F L K + I++ S A+ L Sbjct: 225 NRHN--------LKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQ 276 Query: 311 YIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVA-ARGLDIPAVDWIIQFDPPDD 369 L L H R ++ N + +IC +A G+D P V ++I P Sbjct: 277 RDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKS 336 Query: 370 PRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYL 405 Y GR R + L+F T +++ L+ L Sbjct: 337 VEGYYQESGRAGRDGE-ISHCLLFYTYHDVTRLKRL 371 >2VA8-A nrPDB Length = 715 Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust. Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 7/84 (8%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPP-LLAGRDVLGAAKTGSGKTLAFLIPAIE 102 E+LKL ++ I+K G + Q + LL G +L + TGSGKTL I Sbjct: 10 IEDLKLPSNVIEIIKKRGIKKLNPPQTEAVKKGLLEGNRLLLTSPTGSGKTL------IA 63 Query: 103 LLHSLKFKPRNGTGIIVITPTREL 126 + + F +NG I +TP R L Sbjct: 64 EMGIISFLLKNGGKAIYVTPLRAL 87 >5K9T-A nrPDB Length = 578 Score = 36.6 bits (83), Expect = 0.027, Method: Compositional matrix adjust. Identities = 47/149 (31%), Positives = 63/149 (42%), Gaps = 26/149 (17%) Query: 87 KTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFG 146 +TG GKTL +PA L++L G G+ V+T LA + R L EF T G Sbjct: 91 RTGEGKTLTATLPA--YLNAL-----TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVG 143 Query: 147 IVIGG----ANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGF-----VFKNLKALIIDE 197 I + G A R A + G N D+L++ F V + L ++DE Sbjct: 144 INLPGMPAPAKREAYAADITYGTNNEYG-----FDYLRDNMAFSPAARVQRKLHYALVDE 198 Query: 198 ADRILEIGFEDEMRQ-IIKILPNEDRQSM 225 D IL DE R +I P ED M Sbjct: 199 VDSIL----IDEARTPLIISGPAEDSSEM 223 >2FSI-A nrPDB Length = 853 Score = 36.6 bits (83), Expect = 0.029, Method: Compositional matrix adjust. Identities = 47/153 (30%), Positives = 64/153 (41%), Gaps = 26/153 (16%) Query: 83 LGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS 142 + +TG GKTL +PA L++L G G+ V+T LA + R L EF Sbjct: 91 IAEMRTGEGKTLTATLPA--YLNAL-----TGKGVHVVTVNDYLAQRDAENNRPLFEFLG 143 Query: 143 QTFGIVIGG----ANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGF-----VFKNLKAL 193 T GI + G A R A + G N D+L++ F V + L Sbjct: 144 LTVGINLPGMPAPAKREAYAADITYGTNNEYG-----FDYLRDNMAFSPEERVQRKLHYA 198 Query: 194 IIDEADRILEIGFEDEMRQ-IIKILPNEDRQSM 225 ++DE D IL DE R +I P ED M Sbjct: 199 LVDEVDSIL----IDEARTPLIISGPAEDSSEM 227 >3BXZ-A nrPDB Length = 471 Score = 35.8 bits (81), Expect = 0.048, Method: Compositional matrix adjust. Identities = 39/125 (31%), Positives = 54/125 (43%), Gaps = 21/125 (16%) Query: 87 KTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFG 146 +TG GKTL +PA L++L G G+ V+T LA + R L EF T G Sbjct: 105 RTGEGKTLTATLPA--YLNAL-----TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVG 157 Query: 147 IVIGG----ANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGF-----VFKNLKALIIDE 197 I + G A R A + G N D+L++ F V + L ++DE Sbjct: 158 INLPGMPAPAKREAYAADITYGTNNEYG-----FDYLRDNMAFSPEERVQRKLHYALVDE 212 Query: 198 ADRIL 202 D IL Sbjct: 213 VDSIL 217 >6BOG-A nrPDB Length = 968 Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust. Identities = 39/184 (21%), Positives = 74/184 (40%), Gaps = 17/184 (9%) Query: 205 GFEDEMRQIIKI-LPNEDRQSMLFSATQTTK--VEDLARISLRPGPLFINVVPETDNSTA 261 GF IK+ LP + + ++ S + ED AR L P ++ E DN+T Sbjct: 427 GFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEF--EGDNATW 484 Query: 262 DGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNY---IDLPVLE 318 + D R L +L ++ +K++V + + ++L I V Sbjct: 485 ---------WNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFH 535 Query: 319 LHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVG 378 ++ R +F + +L+C+++ + G + ++ FD P +P R+G Sbjct: 536 EGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIG 595 Query: 379 RTAR 382 R R Sbjct: 596 RLDR 599 >2NMV-A nrPDB Length = 661 Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust. Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 5/86 (5%) Query: 307 ELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDP 366 + L I + V LH + K +R + + +L+ ++ GLDIP V + D Sbjct: 463 DYLKEIGIKVNYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDA 522 Query: 367 PDD-----PRDYIHRVGRTARGTKGK 387 + R I +GR AR +G+ Sbjct: 523 DKEGFLRSERSLIQTIGRAARNAEGR 548 >4A2W-A nrPDB Length = 936 Score = 32.7 bits (73), Expect = 0.42, Method: Compositional matrix adjust. Identities = 27/136 (19%), Positives = 56/136 (41%), Gaps = 10/136 (7%) Query: 67 SVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTREL 126 S Q P + G++ L A TGSGKT ++ H + P +V T+ Sbjct: 251 SYQIELAQPAINGKNALICAPTGSGKTFVSILIC---EHHFQNMPAGRKAKVVFLATK-- 305 Query: 127 ALQIFGVARELMEFHSQTFGIVIGGANRRQ----EAEKLMKGVNMLIATPGRLLDHLQNT 182 + ++ + + + H + G + G + EK+++ ++++ TP L++ ++ Sbjct: 306 -VPVYEQQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIEDSDIIVVTPQILVNSFEDG 364 Query: 183 KGFVFKNLKALIIDEA 198 +I DE Sbjct: 365 TLTSLSIFTLMIFDEC 380 >4A2Q-A nrPDB Length = 797 Score = 32.3 bits (72), Expect = 0.54, Method: Compositional matrix adjust. Identities = 27/136 (19%), Positives = 56/136 (41%), Gaps = 10/136 (7%) Query: 67 SVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTREL 126 S Q P + G++ L A TGSGKT ++ H + P +V T+ Sbjct: 251 SYQIELAQPAINGKNALICAPTGSGKTFVSILIC---EHHFQNMPAGRKAKVVFLATK-- 305 Query: 127 ALQIFGVARELMEFHSQTFGIVIGGANRRQ----EAEKLMKGVNMLIATPGRLLDHLQNT 182 + ++ + + + H + G + G + EK+++ ++++ TP L++ ++ Sbjct: 306 -VPVYEQQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIEDSDIIVVTPQILVNSFEDG 364 Query: 183 KGFVFKNLKALIIDEA 198 +I DE Sbjct: 365 TLTSLSIFTLMIFDEC 380 >4A36-A nrPDB Length = 556 Score = 32.0 bits (71), Expect = 0.70, Method: Compositional matrix adjust. Identities = 27/136 (19%), Positives = 56/136 (41%), Gaps = 10/136 (7%) Query: 67 SVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTREL 126 S Q P + G++ L A TGSGKT ++ H + P +V T+ Sbjct: 10 SYQIELAQPAINGKNALICAPTGSGKTFVSILIC---EHHFQNMPAGRKAKVVFLATK-- 64 Query: 127 ALQIFGVARELMEFHSQTFGIVIGGANRRQ----EAEKLMKGVNMLIATPGRLLDHLQNT 182 + ++ + + + H + G + G + EK+++ ++++ TP L++ ++ Sbjct: 65 -VPVYEQQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIEDSDIIVVTPQILVNSFEDG 123 Query: 183 KGFVFKNLKALIIDEA 198 +I DE Sbjct: 124 TLTSLSIFTLMIFDEC 139 >2WWY-A nrPDB Length = 591 Score = 31.2 bits (69), Expect = 0.97, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 21/34 (61%) Query: 68 VQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAI 101 +Q TI +AG++V TG GK+L + +PA+ Sbjct: 48 LQLETINVTMAGKEVFLVMPTGGGKSLCYQLPAL 81 >6G19-A nrPDB Length = 696 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 11/155 (7%) Query: 69 QARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELAL 128 Q P L G++++ TGSGKT + + L K +G I+++ LA Sbjct: 7 QMEVAQPALDGKNIIICLPTGSGKTRVAVYITKDHLDKKKQASESGKVIVLVNKVM-LAE 65 Query: 129 QIFGVARELMEFHSQTFGIV--IGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTK--- 183 Q+F +E + + + I+ G + +++K +++I+T L + L N + Sbjct: 66 QLF--RKEFNPYLKKWYRIIGLSGDTQLKISFPEVVKSYDVIISTAQILENSLLNLESGD 123 Query: 184 --GFVFKNLKALIIDEADRI-LEIGFEDEMRQIIK 215 G + +IIDE E + + MR+ +K Sbjct: 124 DDGVQLSDFSLIIIDECHHTNKEAVYNNIMRRYLK 158 >1D9Z-A nrPDB Length = 657 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 20/78 (25%), Positives = 32/78 (41%), Gaps = 5/78 (6%) Query: 314 LPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDD---- 369 + V LH + K +R + + +L+ ++ GLDIP V + D + Sbjct: 469 IKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLR 528 Query: 370 -PRDYIHRVGRTARGTKG 386 R I +GR AR G Sbjct: 529 SERSLIQTIGRAARNANG 546 >1TF2-A nrPDB Length = 844 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 33/126 (26%), Positives = 57/126 (45%), Gaps = 15/126 (11%) Query: 83 LGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS 142 + KTG GKTL +P L++L G G+ V+T LA + ++ EF Sbjct: 100 IAEMKTGEGKTLTSTLPV--YLNAL-----TGKGVHVVTVNEYLASRDAEQMGKIFEFLG 152 Query: 143 QTFGIVIGGANRRQEAEKLMKGVNMLIATPGRL-LDHLQNT-----KGFVFKNLKALIID 196 T G+ + ++ ++ E ++ +T L D+L++ + V + L +ID Sbjct: 153 LTVGLNLNSMSKDEKREAY--AADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVID 210 Query: 197 EADRIL 202 E D IL Sbjct: 211 EVDSIL 216 >5TNU-A nrPDB Length = 459 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 24/114 (21%), Positives = 47/114 (41%), Gaps = 5/114 (4%) Query: 269 VVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKR 328 + +S + L L+ + +KIIVF ++ +PV+ K + +R Sbjct: 324 IAVNSQSKIEKLREILQEYKNEKIIVFTRDTQMAYRISKTFL---IPVVTY--KTDKDER 378 Query: 329 TNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR 382 +F + E +++ + V G+D+P I R ++ R+GR R Sbjct: 379 EEILQKFRDGEYRVIVASTVFDEGVDVPDATLAIVMGGYGTKRQFLQRLGRILR 432 >5JCF-A nrPDB Length = 701 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 31/161 (19%), Positives = 65/161 (40%), Gaps = 6/161 (3%) Query: 60 MGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIV 119 MG T+ Q P L G +++ TGSGKT + + L + G I++ Sbjct: 3 MGDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVL 62 Query: 120 ITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATP----GRL 175 + + + ++ Q G+ G + + +++K +++I T L Sbjct: 63 VNKVPLVEQHLRKEFNPFLKHWYQVIGLS-GDSELKISFPEVVKRYDVIICTAQILENSL 121 Query: 176 LDHLQNTKGFVFKNLKALIIDEADRILEIG-FEDEMRQIIK 215 L+ + + + +IID+ + G + + MR+ +K Sbjct: 122 LNATEEDESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLK 162 >3B6E-A nrPDB Length = 216 Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust. Identities = 32/137 (23%), Positives = 59/137 (43%), Gaps = 10/137 (7%) Query: 69 QARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELAL 128 Q P L G++++ TGSGKT + A + L K G I+++ L Sbjct: 38 QMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVL-LVE 96 Query: 129 QIFGVARELMEFHSQTFGIV--IGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTK--- 183 Q+F +E F + + ++ G + +++K +++I+T L + L N + Sbjct: 97 QLF--RKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGE 154 Query: 184 --GFVFKNLKALIIDEA 198 G + +IIDE Sbjct: 155 DAGVQLSDFSLIIIDEC 171 >5JBJ-A nrPDB Length = 680 Score = 29.6 bits (65), Expect = 3.5, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 2/42 (4%) Query: 323 QKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQF 364 Q +Q+ T F + E +L T VA GLDIP + ++++ Sbjct: 421 QNEQQDVITLFRY--GELNLLFSTSVAEEGLDIPECNIVVRY 460 >6FWS-A nrPDB Length = 716 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 13/25 (52%), Positives = 17/25 (68%) Query: 79 GRDVLGAAKTGSGKTLAFLIPAIEL 103 GR + A TG GKTL++LIP I + Sbjct: 47 GRHLAIEAPTGVGKTLSYLIPGIAI 71 >5EUL-A nrPDB Length = 836 Score = 29.3 bits (64), Expect = 4.8, Method: Compositional matrix adjust. Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 15/122 (12%) Query: 87 KTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFG 146 KTG GKTL +P L++L G G+ V+T LA + ++ EF T G Sbjct: 101 KTGEGKTLTSTLPV--YLNAL-----TGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVG 153 Query: 147 IVIGGANRRQEAEKLMKGVNMLIATPGRL-LDHLQNT-----KGFVFKNLKALIIDEADR 200 + + ++ ++ E ++ +T L D+L++ + V + L +IDE D Sbjct: 154 LNLNSMSKDEKREAY--AADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDS 211 Query: 201 IL 202 IL Sbjct: 212 IL 213 >4GYK-A nrPDB Length = 648 Score = 28.9 bits (63), Expect = 6.0, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 22/78 (28%) Query: 105 HSLKFKPRNGTGIIVITPTRELALQIFGVAREL-------------MEFHSQTFGIVIGG 151 H+L FKP+ G+ I+++ P E I +L M F SQ F Sbjct: 447 HTLPFKPKKGSRILIVAPYEEQTASIEQTIHDLIKRKKIKPVSLSKMNFASQVF------ 500 Query: 152 ANRRQEAEKLMKGVNMLI 169 + E EK +K + +I Sbjct: 501 ---KTEHEKQVKEADYII 515 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6CB1-p nrPDB 729 0.0 2HYI-C nrPDB 457 e-129 4BRW-A nrPDB 418 e-117 4NHO-A nrPDB 414 e-116 4D25-A nrPDB 414 e-116 6CZ5-A nrPDB 413 e-116 2I4I-A nrPDB 413 e-115 5IVL-B nrPDB 412 e-115 3EIQ-A nrPDB 411 e-115 5ANR-B nrPDB 404 e-113 3JCR-F nrPDB 402 e-112 3I62-A nrPDB 397 e-111 5DTU-A nrPDB 397 e-111 2DB3-A nrPDB 396 e-110 2VSX-A nrPDB 395 e-110 1HV8-A nrPDB 390 e-109 1XTI-A nrPDB 388 e-108 6B4I-E nrPDB 383 e-107 5SUQ-A nrPDB 382 e-106 3PEW-A nrPDB 381 e-106 5SUP-A nrPDB 380 e-106 3SQW-A nrPDB 370 e-102 4W7S-A nrPDB 358 3e-99 5ZWN-y nrPDB 357 5e-99 4KBG-A nrPDB 353 1e-97 4LJY-A nrPDB 350 9e-97 6CRM-A nrPDB 343 1e-94 3FHO-A nrPDB 339 2e-93 2Z0M-A nrPDB 336 2e-92 1OYY-A nrPDB 316 1e-86 4Q48-A nrPDB 276 2e-74 1WRB-A nrPDB 273 1e-73 3LY5-A nrPDB 263 1e-70 5LST-A nrPDB 263 2e-70 3BOR-A nrPDB 262 3e-70 5ZBZ-A nrPDB 259 1e-69 4PX9-A nrPDB 258 5e-69 3FE2-A nrPDB 251 5e-67 5H1Y-A nrPDB 241 4e-64 6AIC-A nrPDB 241 6e-64 5GVS-A nrPDB 241 8e-64 2PL3-A nrPDB 240 1e-63 1QVA-A nrPDB 240 1e-63 3BER-A nrPDB 237 7e-63 5GJU-A nrPDB 237 8e-63 2GXQ-A nrPDB 236 2e-62 1VEC-A nrPDB 235 3e-62 1T6N-A nrPDB 232 3e-61 3IUY-A nrPDB 229 2e-60 3FHC-B nrPDB 228 4e-60 3FMO-B nrPDB 228 5e-60 1Q0U-A nrPDB 212 3e-55 2KBE-A nrPDB 207 7e-54 2OXC-A nrPDB 195 3e-50 3DKP-A nrPDB 195 5e-50 1GM5-A nrPDB 184 8e-47 5V9X-A nrPDB 177 9e-45 1WP9-A nrPDB 113 2e-25 2FWR-A nrPDB 110 1e-24 Sequences not found previously or not previously below threshold: 4CDG-A nrPDB 197 1e-50 2WWY-A nrPDB 177 9e-45 5LBA-B nrPDB 172 2e-43 5LB8-A nrPDB 172 2e-43 2VA8-A nrPDB 116 2e-26 2P6R-A nrPDB 112 6e-25 2ZJ8-A nrPDB 108 7e-24 5AGA-A nrPDB 94 1e-19 5TNU-A nrPDB 86 4e-17 1D9Z-A nrPDB 82 7e-16 2NMV-A nrPDB 77 2e-14 5JCF-A nrPDB 74 2e-13 6G19-A nrPDB 74 2e-13 5JBJ-A nrPDB 73 4e-13 4GL2-A nrPDB 72 4e-13 3P4X-A nrPDB 72 8e-13 5N8S-A nrPDB 71 1e-12 6C90-A nrPDB 71 1e-12 1C4O-A nrPDB 71 1e-12 5VHD-D nrPDB 68 8e-12 3TBK-A nrPDB 68 1e-11 2OCA-A nrPDB 67 2e-11 3B6E-A nrPDB 64 1e-10 6BOG-A nrPDB 64 1e-10 5GM6-Y nrPDB 64 2e-10 4ON9-A nrPDB 63 2e-10 6F4A-B nrPDB 63 2e-10 5D0U-A nrPDB 63 3e-10 4BPB-A nrPDB 63 3e-10 4A2W-A nrPDB 63 4e-10 4A2Q-A nrPDB 62 5e-10 5I8Q-A nrPDB 62 5e-10 5XDR-A nrPDB 60 2e-09 4A36-A nrPDB 60 2e-09 4A4Z-A nrPDB 60 2e-09 6ID1-V nrPDB 60 3e-09 5FMF-1 nrPDB 59 4e-09 4CBI-A nrPDB 59 4e-09 5WX1-A nrPDB 59 5e-09 6HEG-A nrPDB 58 7e-09 5SVA-Z nrPDB 58 7e-09 5WSO-A nrPDB 57 2e-08 6I3O-A nrPDB 55 8e-08 4OK6-A nrPDB 55 1e-07 4B6E-A nrPDB 54 1e-07 4XGT-A nrPDB 54 2e-07 6FA9-A nrPDB 54 2e-07 3BXZ-A nrPDB 54 2e-07 2ZJO-A nrPDB 53 4e-07 6FTX-W nrPDB 52 5e-07 5K8T-A nrPDB 52 7e-07 5IY9-V nrPDB 52 7e-07 3MWY-W nrPDB 52 7e-07 5OQJ-7 nrPDB 51 1e-06 2QEQ-A nrPDB 51 1e-06 6NMI-A nrPDB 51 1e-06 5OF4-A nrPDB 51 1e-06 5HZR-A nrPDB 51 1e-06 5X0Y-O nrPDB 51 1e-06 5WDX-A nrPDB 51 1e-06 1YKS-A nrPDB 51 2e-06 5JXT-B nrPDB 50 3e-06 5JXR-A nrPDB 50 3e-06 3RC8-A nrPDB 50 3e-06 5GN1-A nrPDB 49 4e-06 6DCR-A nrPDB 48 1e-05 4UAQ-A nrPDB 47 2e-05 4ERN-A nrPDB 47 3e-05 5K9T-A nrPDB 47 3e-05 2Z83-A nrPDB 46 3e-05 2FSI-A nrPDB 46 5e-05 3DIN-A nrPDB 45 8e-05 4NL8-A nrPDB 44 1e-04 2BMF-A nrPDB 44 1e-04 3H1T-A nrPDB 44 2e-04 1Z6A-A nrPDB 43 3e-04 2WV9-A nrPDB 43 3e-04 2V8O-A nrPDB 43 3e-04 1NL3-A nrPDB 43 3e-04 1Z5Z-A nrPDB 43 3e-04 2JLW-A nrPDB 42 5e-04 2WZQ-A nrPDB 42 7e-04 2V6J-A nrPDB 41 0.001 5EUL-A nrPDB 41 0.002 1TF2-A nrPDB 41 0.002 1Z3I-X nrPDB 40 0.002 1RIF-A nrPDB 39 0.006 4QQW-A nrPDB 38 0.010 6FWS-A nrPDB 38 0.012 2FZ4-A nrPDB 35 0.097 2IPC-A nrPDB 33 0.31 6EG3-A nrPDB 33 0.39 1PEQ-A nrPDB 33 0.44 2NQ2-C nrPDB 32 0.52 6D00-1 nrPDB 32 0.70 1NLZ-A nrPDB 32 0.89 5B55-A nrPDB 32 0.90 5H8W-A nrPDB 31 1.2 5O6D-A nrPDB 30 1.8 3M6A-A nrPDB 30 2.0 3J1C-A nrPDB 30 2.2 3EAG-A nrPDB 30 2.6 2IUS-A nrPDB 30 2.7 1F4U-A nrPDB 30 3.8 4ZIR-B nrPDB 29 4.7 1CTU-A nrPDB 29 5.0 1YID-B nrPDB 29 5.6 1EU1-A nrPDB 28 6.6 5FL3-A nrPDB 28 6.8 3S1A-A nrPDB 28 7.5 6GAZ-Aa nrPDB 28 7.7 4TLD-A nrPDB 28 8.7 >6CB1-p nrPDB Length = 505 Score = 729 bits (1883), Expect = 0.0, Method: Composition-based stats. Identities = 505/505 (100%), Positives = 505/505 (100%) Query: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM 60 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM Sbjct: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM 60 Query: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI Sbjct: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 Query: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ Sbjct: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 Query: 181 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR 240 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR Sbjct: 181 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR 240 Query: 241 ISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCN 300 ISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCN Sbjct: 241 ISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCN 300 Query: 301 SVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDW 360 SVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDW Sbjct: 301 SVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDW 360 Query: 361 IIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPEN 420 IIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPEN Sbjct: 361 IIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPEN 420 Query: 421 KIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAKVAKSYGFP 480 KIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAKVAKSYGFP Sbjct: 421 KIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAKVAKSYGFP 480 Query: 481 VPPKVNITIGASGKTPNTKRRKTHK 505 VPPKVNITIGASGKTPNTKRRKTHK Sbjct: 481 VPPKVNITIGASGKTPNTKRRKTHK 505 >2HYI-C nrPDB Length = 413 Score = 457 bits (1175), Expect = e-129, Method: Composition-based stats. Identities = 114/408 (27%), Positives = 208/408 (50%), Gaps = 21/408 (5%) Query: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM 60 MAT + R R + + V E TS++ + P F+ + L + L+ I Sbjct: 7 MATSGSARKRLLKEEDMTKV-EFETSEEVDVTP---------TFDTMGLREDLLRGIYAY 56 Query: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 GF +++Q R I ++ GRDV+ +++G+GKT F I ++ L + T +++ Sbjct: 57 GFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRE----TQALIL 112 Query: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 PTRELA+QI L ++ + IGG N ++ KL G +++ TPGR+ D + Sbjct: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMI- 171 Query: 181 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR 240 + + +K L++DEAD +L GF++++ + + LP Q +L SAT ++ ++ Sbjct: 172 RRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPA-TQVVLISATLPHEILEMTN 230 Query: 241 ISLRPGPLFINVVPETDNSTADGLEQGYVVCD-SDKRFLLLFSFLKRNQKKKIIVFLSSC 299 + I ++ + D T +G++Q +V + + +F L + ++F ++ Sbjct: 231 KFMTDP---IRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTK 287 Query: 300 NSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVD 359 V + E + + V +HG Q++R + EF + +LI TDV ARGLD+P V Sbjct: 288 RKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVS 347 Query: 360 WIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKA 407 II +D P++ YIHR+GR+ R + KG ++ F+ +++ LR ++ Sbjct: 348 LIINYDLPNNRELYIHRIGRSGRYGR-KGVAINFVKNDDIRILRDIEQ 394 >4BRW-A nrPDB Length = 377 Score = 418 bits (1074), Expect = e-117, Method: Composition-based stats. Identities = 118/366 (32%), Positives = 186/366 (50%), Gaps = 11/366 (3%) Query: 43 KFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE 102 FE+ L + L I + GF + +Q IP + GRD+L AK G+GKT AF+IP +E Sbjct: 2 TFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTLE 61 Query: 103 LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLM 162 + N +++ PTRELALQ V R L + + + GG N R + +L Sbjct: 62 KVKPKL----NKIQALIMVPTRELALQTSQVVRTLGKHCGISCMVTTGGTNLRDDILRLN 117 Query: 163 KGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDR 222 + V++L+ TPGR+LD L + K + I+DEAD++L F+ + QI+ LP Sbjct: 118 ETVHILVGTPGRVLD-LASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLP-PTH 175 Query: 223 QSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFS 282 QS+LFSAT V++ L P IN++ E T G+ Q Y + ++ L + Sbjct: 176 QSLLFSATFPLTVDEFMDKHLHK-PYEINLMEE---LTLKGITQYYAFVEERQKLHCLNT 231 Query: 283 FLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGI 342 + Q + I+F +S N V+ A+ + + H + KQQ+R F EF + Sbjct: 232 LFSKLQINQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRT 291 Query: 343 LICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFL 402 L+C+D+ RG+DI AV+ +I FD P Y+HR+GR+ R G ++ + N+ L Sbjct: 292 LVCSDLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFG-HLGLAINLINWNDRFNL 350 Query: 403 RYLKAS 408 ++ Sbjct: 351 YKIEQE 356 >4NHO-A nrPDB Length = 488 Score = 414 bits (1065), Expect = e-116, Method: Composition-based stats. Identities = 125/448 (27%), Positives = 211/448 (47%), Gaps = 36/448 (8%) Query: 12 SESTEEPVVDEKSTSKQNNAAPEGEQT-TCVEKFEELKLSQPTLKAIEKMGFTTMTSVQA 70 + E D + + + +G + + +++ L L+ I+K G+ T +Q Sbjct: 28 KKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQR 87 Query: 71 RTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPR-----NGTGIIVITPTRE 125 + IP L RD++G A+TGSGKT AFLIP + + +L R G I++ PTRE Sbjct: 88 QAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRE 147 Query: 126 LALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGF 185 LA QI + + VIGG +R + +L G ++IATPGRL+D L+N + Sbjct: 148 LAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLEN-RYL 206 Query: 186 VFKNLKALIIDEADRILEIGFEDEMRQIIKILP-------------------------NE 220 V +++DEADR++++GFE ++++I++ +P ++ Sbjct: 207 VLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHK 266 Query: 221 DRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLL 280 RQ+++F+AT VE LAR LR + V + + +EQ + ++ L Sbjct: 267 YRQTVMFTATMPPAVERLARSYLRRPAV---VYIGSAGKPHERVEQKVFLMSESEKRKKL 323 Query: 281 FSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAER 340 + L++ II+F++ A+ L + LHG + Q++R + Sbjct: 324 LAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAK 383 Query: 341 GILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELG 400 IL+ TDVA RG+DI V ++ +D + DYIHR+GRT R K G ++ FLT + Sbjct: 384 DILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKS-GVAITFLTKEDSA 442 Query: 401 FLRYLKASKVPLNEYEFPENKIANVQSQ 428 LK + + P + +Q Sbjct: 443 VFYELKQAILESPVSSCPPELANHPDAQ 470 >4D25-A nrPDB Length = 434 Score = 414 bits (1063), Expect = e-116, Method: Composition-based stats. Identities = 120/410 (29%), Positives = 211/410 (51%), Gaps = 23/410 (5%) Query: 19 VVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLA 78 D + P +E FE L + L + K G+ T +Q IP +++ Sbjct: 32 KFDHIAVKVSGENPPRP-----IESFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMS 86 Query: 79 GRDVLGAAKTGSGKTLAFLIPAIELL--HSLKFKPRNG---TGIIVITPTRELALQIFGV 133 GRD++G A+TGSGKT AFL+P I +L NG +I+++PTREL LQIF Sbjct: 87 GRDLMGCAQTGSGKTAAFLVPIINMLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNE 146 Query: 134 ARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKAL 193 AR+ + GG R + + + +G ++L+ATPGRL D ++ + F +++ + Sbjct: 147 ARKFSYGSVLKVAVAYGGTAVRHQGDNIARGCHILVATPGRLHDFVERNR-VSFGSVRFV 205 Query: 194 IIDEADRILEIGFEDEMRQII---KILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFI 250 ++D+AD +L++GF + +++ ++ RQ+++FSAT ++ LA L LF+ Sbjct: 206 VLDQADCMLDMGFMPSIEKMMLHPTMVETTKRQTLMFSATFPEDIQHLAGRFL-NNYLFV 264 Query: 251 NVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLN 310 V ST +EQ ++ ++ L ++ N K+I+VF+ + + + A +L+ Sbjct: 265 AVGIVGGAST--DVEQIFIEVTKYEKRNSLKQLIEENDGKRILVFVETKRNADFIAAMLS 322 Query: 311 YIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDP 370 L +HG + Q++R F + + IL+ T VAARGLDI VD ++ +D P Sbjct: 323 EQQLLTSSIHGDRMQREREEALQNFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSI 382 Query: 371 RDYIHRVGRTARGTKGKGKSLMFLTPNELGFL-----RYLKASKVPLNEY 415 +Y+HR+GRT R +GK++ F ++ L + L+ + + ++ Sbjct: 383 DEYVHRIGRTGRVG-NRGKAVSFYDSDQDLALVADLSKILRQADQSVPDF 431 >6CZ5-A nrPDB Length = 480 Score = 413 bits (1062), Expect = e-116, Method: Composition-based stats. Identities = 127/397 (31%), Positives = 200/397 (50%), Gaps = 29/397 (7%) Query: 29 NNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKT 88 NN P +E F ++++ + + IE +T T VQ IP + RD++ A+T Sbjct: 46 NNCPPH------IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQT 99 Query: 89 GSGKTLAFLIPAIEL---------LHSLKFKPRNG-----TGIIVITPTRELALQIFGVA 134 G GKT AFL+P + L ++K R G +V+ PTRELA+QI+ A Sbjct: 100 GCGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEA 159 Query: 135 RELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALI 194 R+ +V GGA+ Q+ L +G ++L+ATPGRL+D ++ K K L+ Sbjct: 160 RKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLV 218 Query: 195 IDEADRILEIGFEDEMRQIIK---ILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFIN 251 +DEADR+L++GFE ++R+I++ + P R +M+FSAT +++ LAR L +I Sbjct: 219 LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDE---YIF 275 Query: 252 VVPETDNSTADGLEQGYV-VCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLN 310 + ST++ + Q V V +SDKR LL + +VF+ + + L Sbjct: 276 LAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLY 335 Query: 311 YIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDP 370 + +HG + Q+ R +F + + IL+ T VAARGLDI V +I FD P D Sbjct: 336 HEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDI 395 Query: 371 RDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKA 407 +Y+HR+GRT R G + F + + L Sbjct: 396 EEYVHRIGRTGRVG-NLGLATSFFNERNINITKDLLD 431 >2I4I-A nrPDB Length = 417 Score = 413 bits (1061), Expect = e-115, Method: Composition-based stats. Identities = 128/397 (32%), Positives = 201/397 (50%), Gaps = 29/397 (7%) Query: 29 NNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKT 88 NN P +E F ++++ + + IE +T T VQ IP + RD++ A+T Sbjct: 8 NNCPPH------IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQT 61 Query: 89 GSGKTLAFLIPAIEL---------LHSLKFKPRNG-----TGIIVITPTRELALQIFGVA 134 GSGKT AFL+P + L ++K R G +V+ PTRELA+QI+ A Sbjct: 62 GSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEA 121 Query: 135 RELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALI 194 R+ +V GGA+ Q+ L +G ++L+ATPGRL+D ++ K K L+ Sbjct: 122 RKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLV 180 Query: 195 IDEADRILEIGFEDEMRQIIK---ILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFIN 251 +DEADR+L++GFE ++R+I++ + P R +M+FSAT +++ LAR L +I Sbjct: 181 LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDE---YIF 237 Query: 252 VVPETDNSTADGLEQGYV-VCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLN 310 + ST++ + Q V V +SDKR LL + +VF+ + + L Sbjct: 238 LAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLY 297 Query: 311 YIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDP 370 + +HG + Q+ R +F + + IL+ T VAARGLDI V +I FD P D Sbjct: 298 HEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDI 357 Query: 371 RDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKA 407 +Y+HR+GRT R G + F + + L Sbjct: 358 EEYVHRIGRTGRVG-NLGLATSFFNERNINITKDLLD 393 >5IVL-B nrPDB Length = 429 Score = 412 bits (1060), Expect = e-115, Method: Composition-based stats. Identities = 127/368 (34%), Positives = 197/368 (53%), Gaps = 10/368 (2%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 + F+EL LSQ +KAIE+MGF T +QA+TIP L +DV+G A+TG+GKT AF IP Sbjct: 1 MTTFQELGLSQEVMKAIERMGFEETTPIQAKTIPLSLQNKDVIGQAQTGTGKTAAFGIPI 60 Query: 101 IELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEK 160 +E + +V+ PTRELA+Q+ ++ + GG + ++ Sbjct: 61 VEKVD----VKNGAIQALVVAPTRELAIQVSEELYKIGAVKRVRVLPIYGGQDIERQIRA 116 Query: 161 LMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNE 220 L K ++++ TPGR++DH+ N +++ +++DEAD +L +GF +++ I+ +P E Sbjct: 117 LKKHPHVIVGTPGRIIDHI-NRGTLRLEHVHTVVLDEADEMLNMGFIEDIEAILSHVPAE 175 Query: 221 DRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLL 280 RQ++LFSAT + +A + L V + T ++Q Y+ K+F +L Sbjct: 176 -RQTLLFSATMPDPIRRIAERFMNEPEL---VKVKAKEMTVPNIQQYYLEVHEKKKFDIL 231 Query: 281 FSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAER 340 L + IVF + V AE LN +HG Q KR + +F Sbjct: 232 TRLLDIQAPELAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLSQAKRLSVLRKFKEGAI 291 Query: 341 GILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELG 400 IL+ TDVAARGLDI V + FD P DP Y+HR+GRT R K G ++ F+TP E+G Sbjct: 292 EILVATDVAARGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGK-TGVAMTFVTPREIG 350 Query: 401 FLRYLKAS 408 L +++ + Sbjct: 351 QLHHIERT 358 >3EIQ-A nrPDB Length = 414 Score = 411 bits (1056), Expect = e-115, Method: Composition-based stats. Identities = 114/408 (27%), Positives = 202/408 (49%), Gaps = 22/408 (5%) Query: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM 60 M+ + RSRD+ + E V+ F+++ LS+ L+ I Sbjct: 9 MSASQDSRSRDNGPDGM----------EPEGVIESNWNEIVDSFDDMNLSESLLRGIYAY 58 Query: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 GF +++Q R I P + G DV+ A++G+GKT F I ++ + T +V+ Sbjct: 59 GFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLK----ATQALVL 114 Query: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKL-MKGVNMLIATPGRLLDHL 179 PTRELA QI V L ++ + IGG N R E +KL M+ ++++ TPGR+ D L Sbjct: 115 APTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDML 174 Query: 180 QNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLA 239 N + K +K ++DEAD +L GF+D++ I + L N + Q +L SAT + V ++ Sbjct: 175 -NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKL-NSNTQVVLLSATMPSDVLEVT 232 Query: 240 RISLRPGPLFINVVPETDNSTADGLEQGYVVCD-SDKRFLLLFSFLKRNQKKKIIVFLSS 298 + +R I ++ + + T +G+ Q Y+ + + + L + + ++F+++ Sbjct: 233 KKFMRDP---IRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINT 289 Query: 299 CNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAV 358 V + E ++ D V +HG Q++R EF + +LI TD+ ARG+D+ V Sbjct: 290 RRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQV 349 Query: 359 DWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLK 406 +I +D P + +YIHR+ KG ++ +T + LR ++ Sbjct: 350 SLVINYDLPTNRENYIHRI-GRGGRFGRKGVAINMVTEEDKRTLRDIE 396 >5ANR-B nrPDB Length = 378 Score = 404 bits (1038), Expect = e-113, Method: Composition-based stats. Identities = 115/366 (31%), Positives = 193/366 (52%), Gaps = 12/366 (3%) Query: 43 KFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE 102 +FE+ L + L I +MG+ + +Q +IP L+GRD+L AK G+GK+ A+LIP +E Sbjct: 6 EFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLE 65 Query: 103 LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS-QTFGIVIGGANRRQEAEKL 161 L ++ +VI PTRELALQ+ + ++ + GG N R + +L Sbjct: 66 RLD----LKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRL 121 Query: 162 MKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNED 221 V+++IATPGR+LD ++ +++ +++DEAD++L F M II LP ++ Sbjct: 122 DDTVHVVIATPGRILDLIKKGVAK-VDHVQMIVLDEADKLLSQDFVQIMEDIILTLP-KN 179 Query: 222 RQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLF 281 RQ +L+SAT V+ L+ P IN++ E T G+ Q Y ++ L Sbjct: 180 RQILLYSATFPLSVQKFMNSHLQK-PYEINLMEE---LTLKGVTQYYAYVTERQKVHCLN 235 Query: 282 SFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERG 341 + R Q + I+F +S V+ A+ ++ + +H K +Q+ R F +F N Sbjct: 236 TLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCR 295 Query: 342 ILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGF 401 L+CTD+ RG+DI AV+ +I FD P Y+HR+GR+ R G ++ +T ++ Sbjct: 296 NLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFG-HLGLAINLITYDDRFN 354 Query: 402 LRYLKA 407 L+ ++ Sbjct: 355 LKSIEE 360 >3JCR-F nrPDB Length = 820 Score = 402 bits (1034), Expect = e-112, Method: Composition-based stats. Identities = 125/448 (27%), Positives = 210/448 (46%), Gaps = 36/448 (8%) Query: 12 SESTEEPVVDEKSTSKQNNAAPEGEQT-TCVEKFEELKLSQPTLKAIEKMGFTTMTSVQA 70 + E D + + + +G + + +++ L L+ I+K G+ T +Q Sbjct: 360 KKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQR 419 Query: 71 RTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPR-----NGTGIIVITPTRE 125 + IP L RD++G A+TGSGKT AFLIP + + +L R G I++ PTRE Sbjct: 420 QAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRE 479 Query: 126 LALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGF 185 LA QI + + VIGG +R + +L G ++IATPGRL+D L+N + Sbjct: 480 LAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLEN-RYL 538 Query: 186 VFKNLKALIIDEADRILEIGFEDEMRQIIKILPNED------------------------ 221 V +++DEADR++++GFE ++++I++ +P + Sbjct: 539 VLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHK 598 Query: 222 -RQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLL 280 RQ+++F+AT VE LAR LR + V + + +EQ + ++ L Sbjct: 599 YRQTVMFTATMPPAVERLARSYLRRPAV---VYIGSAGKPHERVEQKVFLMSESEKRKKL 655 Query: 281 FSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAER 340 + L++ II+F++ A+ L + LHG + Q++R + Sbjct: 656 LAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAK 715 Query: 341 GILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELG 400 IL+ TDVA RG+DI V ++ +D + DYIHR+GRT R K G ++ FLT + Sbjct: 716 DILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKS-GVAITFLTKEDSA 774 Query: 401 FLRYLKASKVPLNEYEFPENKIANVQSQ 428 LK + + P + +Q Sbjct: 775 VFYELKQAILESPVSSCPPELANHPDAQ 802 >3I62-A nrPDB Length = 563 Score = 397 bits (1021), Expect = e-111, Method: Composition-based stats. Identities = 156/452 (34%), Positives = 243/452 (53%), Gaps = 34/452 (7%) Query: 5 SNKRSRDSESTEEPVVDEKSTSKQNNAAPE--GEQTTCVEKFEELKLSQPTLKAIEKMGF 62 S R+R E +E D+ + SK + E ++ T EE L + KAI +M F Sbjct: 33 SRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEF 92 Query: 63 TTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 +T VQ +TI P+L+ DV+ AKTG+GKT AFLIP + L + KF + +++ Sbjct: 93 PGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIV 152 Query: 121 TPTRELALQIFGVAREL--MEFHSQTFGIV--IGGANRRQEAEKLMK-GVNMLIATPGRL 175 PTR+LALQI +++ M + + + V +GG + R K+ K N++IATPGRL Sbjct: 153 APTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATPGRL 212 Query: 176 LDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQ------SMLFSA 229 +D L+ F+ + ++DEADR+LEIGF D++ I IL ++ + ++LFSA Sbjct: 213 IDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFSA 272 Query: 230 TQTTKVEDLARISL-RPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLK--- 285 T KV+ LA + + LF++ V + + + ++Q V+ S+K +F+ ++ Sbjct: 273 TLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVI--SEKFANSIFAAVEHIK 330 Query: 286 -----RNQKKKIIVFLSSCNSVKYYAELLNY---IDLPVLELHGKQKQQKRTNTFFEFCN 337 R+ K I+F + + +L DLP+LE HGK Q KRT+ F Sbjct: 331 KQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKK 390 Query: 338 AERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPN 397 E GIL+CTDV ARG+D P V ++Q P + +YIHR+GRTAR K +G S++F+ + Sbjct: 391 DESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGK-EGSSVLFICKD 449 Query: 398 ELGFLRYLKASK----VPLNEYEFPENKIANV 425 EL F+R L+ +K +YE E + V Sbjct: 450 ELPFVRELEDAKNIVIAKQEKYEPSEEIKSEV 481 >5DTU-A nrPDB Length = 475 Score = 397 bits (1019), Expect = e-111, Method: Composition-based stats. Identities = 128/434 (29%), Positives = 209/434 (48%), Gaps = 44/434 (10%) Query: 32 APEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSG 91 G + +EE L + L + ++G+ T +Q IP L RD++G A TGSG Sbjct: 32 TKGGSIPNPMRNWEESGLPRRLLDIVYRVGYDEPTPIQRAAIPIALQARDLIGVAVTGSG 91 Query: 92 KTLAFLIPAIELLHSLK----FKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGI 147 KT AFL+P + + L + +G +++ PTREL QI AR+ + T Sbjct: 92 KTAAFLLPLLVYISELPPLTEYNKNDGPYALILAPTRELVQQIESEARKFADPLGFTVVS 151 Query: 148 VIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFE 207 ++GG + ++A L G +++ATPGRL+D ++ + VF +I+DEADR+++ GFE Sbjct: 152 IVGGHSLEEQAFALRNGAEIIVATPGRLVDCIER-RLLVFSQCCYVIMDEADRMIDQGFE 210 Query: 208 DEMRQIIKILPNED------------------------RQSMLFSATQTTKVEDLARISL 243 + + +I+ LP + RQ+M+++AT VE +A+ L Sbjct: 211 EPLTKILDALPVSNEKPDTEDAENPQLMSRYLGGRDRYRQTMMYTATMPPTVEKIAKKYL 270 Query: 244 R-PGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQ-KKKIIVFLSSCNS 301 R P + I E ++ +E + DKR L L Q K IIVF++ + Sbjct: 271 RRPAIVTIGNAGEAVDTVEQRVE---FIAGEDKRKRRLQEILNSGQFKPPIIVFVNIKRN 327 Query: 302 VKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWI 361 + A+ + + LHG + Q++R + N + IL+ TD+A RG+D+P V + Sbjct: 328 CEMVAKDIKSWGFSTVTLHGSKTQEQREASLAALRNGQAHILVATDLAGRGIDVPDVSLV 387 Query: 362 IQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKA-------SKVP--L 412 + F+ P Y HR+GRT R K G ++ FL + + LK SKVP L Sbjct: 388 VNFNMPSTIEAYTHRIGRTGRAGKS-GVAITFLGNEDADVMYDLKQIISKSSISKVPEEL 446 Query: 413 NEYEFPENKIANVQ 426 +E ++K V+ Sbjct: 447 RRHEAAQSKPNRVK 460 >2DB3-A nrPDB Length = 434 Score = 396 bits (1018), Expect = e-110, Method: Composition-based stats. Identities = 117/383 (30%), Positives = 198/383 (51%), Gaps = 11/383 (2%) Query: 25 TSKQNNAAPEGEQTTC---VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRD 81 SK NN + + ++ F L + + K G+ T +Q +IP + +GRD Sbjct: 36 FSKYNNIPVKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRD 95 Query: 82 VLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNG-TGIIVITPTRELALQIFGVARELMEF 140 ++ A+TGSGKT AFL+P + L + G +++++PTRELA+QIF AR+ Sbjct: 96 LMACAQTGSGKTAAFLLPILSKLLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFE 155 Query: 141 HSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADR 200 GIV GG + R + E + +G +++IATPGRLLD + T F++ + +++DEADR Sbjct: 156 SYLKIGIVYGGTSFRHQNECITRGCHVVIATPGRLLDFVDRT-FITFEDTRFVVLDEADR 214 Query: 201 ILEIGFEDEMRQII-KILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNS 259 +L++GF ++MR+I+ + + Q+++FSAT +++ +A L+ ++ V Sbjct: 215 MLDMGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLK---NYVFVAIGIVGG 271 Query: 260 TADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLEL 319 ++Q + + L L Q IVF+ + + A L+ + P + Sbjct: 272 ACSDVKQTIYEVNKYAKRSKLIEILSE-QADGTIVFVETKRGADFLASFLSEKEFPTTSI 330 Query: 320 HGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGR 379 HG + Q +R +F N +LI T VA+RGLDI + +I +D P DY+HR+GR Sbjct: 331 HGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGR 390 Query: 380 TARGTKGKGKSLMFLTPNELGFL 402 T R G++ F P + + Sbjct: 391 TGRVGNN-GRATSFFDPEKDRAI 412 >2VSX-A nrPDB Length = 395 Score = 395 bits (1016), Expect = e-110, Method: Composition-based stats. Identities = 108/376 (28%), Positives = 192/376 (51%), Gaps = 12/376 (3%) Query: 34 EGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKT 93 + V KF++++L + L+ + GF +++Q R I P++ G DVL A++G+GKT Sbjct: 14 QTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKT 73 Query: 94 LAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGAN 153 F I A++ + + P+ +++ PTRELALQI V L IGG + Sbjct: 74 GTFSIAALQRIDTSVKAPQ----ALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTS 129 Query: 154 RRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQI 213 ++AE L + +++ TPGR+ D++Q + F +K I+DEAD +L GF++++ QI Sbjct: 130 FVEDAEGL-RDAQIVVGTPGRVFDNIQRRR-FRTDKIKMFILDEADEMLSSGFKEQIYQI 187 Query: 214 IKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDS 273 +LP Q +L SAT V ++ +R + ++ + D T +G++Q YV + Sbjct: 188 FTLLP-PTTQVVLLSATMPNDVLEVTTKFMRNP---VRILVKKDELTLEGIKQFYVNVEE 243 Query: 274 DK-RFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTF 332 ++ ++ L + ++F ++ V+ L V ++ QQ+R Sbjct: 244 EEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIM 303 Query: 333 FEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLM 392 EF + ILI TD+ ARG+D+ V +I +D P + +YIHR+ KG ++ Sbjct: 304 KEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRI-GRGGRFGRKGVAIN 362 Query: 393 FLTPNELGFLRYLKAS 408 F+T ++G +R L+ Sbjct: 363 FVTNEDVGAMRELEKF 378 >1HV8-A nrPDB Length = 367 Score = 390 bits (1002), Expect = e-109, Method: Composition-based stats. Identities = 126/377 (33%), Positives = 197/377 (52%), Gaps = 19/377 (5%) Query: 43 KFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG-RDVLGAAKTGSGKTLAFLIPAI 101 F EL LS L AI GF T +Q + IP L +++ A+TGSGKT +F IP I Sbjct: 7 NFNELNLSDNILNAIRNKGFEKPTDIQMKVIPLFLNDEYNIVAQARTGSGKTASFAIPLI 66 Query: 102 ELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKL 161 EL++ NG I++TPTRELA+Q+ L + + GG + + L Sbjct: 67 ELVNE-----NNGIEAIILTPTRELAIQVADEIESLKGNKNLKIAKIYGGKAIYPQIKAL 121 Query: 162 MKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNED 221 K N+++ TPGR+LDH+ N KN+K I+DEAD +L +GF ++ +I+ N+D Sbjct: 122 -KNANIVVGTPGRILDHI-NRGTLNLKNVKYFILDEADEMLNMGFIKDVEKILNAC-NKD 178 Query: 222 RQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLF 281 ++ +LFSAT ++ +LA+ + FI +EQ YV + ++RF L Sbjct: 179 KRILLFSATMPREILNLAKKYMG-DYSFIKAKINA------NIEQSYVEVNENERFEALC 231 Query: 282 SFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERG 341 LK N++ +VF + K A +L I +HG Q +R F + Sbjct: 232 RLLK-NKEFYGLVFCKTKRDTKELASMLRDIGFKAGAIHGDLSQSQREKVIRLFKQKKIR 290 Query: 342 ILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGF 401 ILI TDV +RG+D+ ++ +I + P +P Y+HR+GRT R K KGK++ + E Sbjct: 291 ILIATDVMSRGIDVNDLNCVINYHLPQNPESYMHRIGRTGRAGK-KGKAISIINRREYKK 349 Query: 402 LRYLKAS-KVPLNEYEF 417 LRY++ + K+ + + +F Sbjct: 350 LRYIERAMKLKIKKLKF 366 >1XTI-A nrPDB Length = 391 Score = 388 bits (997), Expect = e-108, Method: Composition-based stats. Identities = 109/381 (28%), Positives = 193/381 (50%), Gaps = 12/381 (3%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F + L L+AI GF + VQ IP + G DVL AK+G GKT F++ ++ Sbjct: 10 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 69 Query: 104 LHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS-QTFGIVIGGANRRQEAEKLM 162 L + + ++V+ TRELA QI ++ + GG + +++ E L Sbjct: 70 LEPVTGQ----VSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLK 125 Query: 163 KGV-NMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEI-GFEDEMRQIIKILPNE 220 K ++++ TPGR+L L K K++K I+DE D++LE ++++I ++ P+E Sbjct: 126 KNCPHIVVGTPGRIL-ALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHE 184 Query: 221 DRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLL 280 +Q M+FSAT + ++ + R ++ P+ I V ET T GL+Q YV +++ L Sbjct: 185 -KQVMMFSATLSKEIRPVCRKFMQ-DPMEIFVDDETK-LTLHGLQQYYVKLKDNEKNRKL 241 Query: 281 FSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAER 340 F L + ++++F+ S A+LL + P + +H Q++R + + +F + +R Sbjct: 242 FDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQR 301 Query: 341 GILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELG 400 IL+ T++ RG+DI V+ +D P+D Y+HRV R R KG ++ F++ Sbjct: 302 RILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFG-TKGLAITFVSDENDA 360 Query: 401 FLRYLKASKVPLNEYEFPENK 421 + + +N E P+ Sbjct: 361 KILNDVQDRFEVNISELPDEI 381 >6B4I-E nrPDB Length = 430 Score = 383 bits (985), Expect = e-107, Method: Composition-based stats. Identities = 103/398 (25%), Positives = 195/398 (48%), Gaps = 28/398 (7%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLI 98 V+ FEEL+L L+ + MGF + +Q +P +LA ++++ +++G+GKT AF++ Sbjct: 42 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 101 Query: 99 PAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEA 158 + + P+ + ++PT ELALQ V ++ +F+ + N+ + Sbjct: 102 AMLSQVEPANKYPQ----CLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG 157 Query: 159 EKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQIIKIL 217 +K+ + ++I TPG +LD K K +K ++DEAD ++ G +D+ +I ++L Sbjct: 158 QKISEQ--IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRML 215 Query: 218 PNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDS-DKR 276 P + Q +LFSAT V A+ + P P I + + + T D ++Q YV+C S D++ Sbjct: 216 PR-NCQMLLFSATFEDSVWKFAQK-VVPDPNVIKL--KREEETLDTIKQYYVLCSSRDEK 271 Query: 277 FLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFC 336 F L + + ++F + + + A L+ V L G+ ++R F Sbjct: 272 FQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFR 331 Query: 337 NAERGILICTDVAARGLDIPAVDWIIQFDPP------DDPRDYIHRVGRTARGTKGKGKS 390 + +L+ T+V ARG+D+ V +I FD P D Y+HR+GRT R K +G + Sbjct: 332 EGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGK-RGLA 390 Query: 391 LMFLT-PNELGFLRYLKAS------KVPLNEYEFPENK 421 + + + + L ++ ++ ++ + E Sbjct: 391 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKI 428 >5SUQ-A nrPDB Length = 446 Score = 382 bits (981), Expect = e-106, Method: Composition-based stats. Identities = 117/385 (30%), Positives = 190/385 (49%), Gaps = 16/385 (4%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F++ L +AI GF + VQ TIP + G DVL AK+G GKT F++ ++ Sbjct: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 Query: 104 LHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS-QTFGIVIGGANRRQEAEKLM 162 L + + ++VI RELA QI ++ + GG ++AE L Sbjct: 124 LDPVPGE----VAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLK 179 Query: 163 KG---VNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQIIKILP 218 ++++ATPGRL L K ++K +IDE D++LE + ++++I + P Sbjct: 180 NKDTAPHIVVATPGRL-KALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATP 238 Query: 219 NEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFL 278 D+Q M+FSAT + ++ + R L+ PL I V E T GL+Q Y+ + ++ Sbjct: 239 R-DKQVMMFSATLSQEIRPICRRFLQ-NPLEIFVDDEAK-LTLHGLQQYYIKLEEREKNR 295 Query: 279 LLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNA 338 L L + ++I+F+ S +LLN + P + +HG KQ++R + F + Sbjct: 296 KLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDF 355 Query: 339 ERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR-GTKGKGKSLMFLTPN 397 E+ I + TDV RG+DI ++ I +D ++ Y+HRVGR R GTKG S + + Sbjct: 356 EKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKED 415 Query: 398 ELGFLRYLKASKVPLNEYEFPENKI 422 E + + V + EFPE I Sbjct: 416 EEVLAKIQERFDVKIA--EFPEEGI 438 >3PEW-A nrPDB Length = 395 Score = 381 bits (978), Expect = e-106, Method: Composition-based stats. Identities = 109/406 (26%), Positives = 195/406 (48%), Gaps = 34/406 (8%) Query: 39 TCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAF 96 + F+EL L+ LK I M F + +Q R +P LL R+++ +++G+GKT AF Sbjct: 2 AMAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAF 61 Query: 97 LIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGA-NRR 155 + + ++ P+ I + P+RELA Q V +E+ +F T +++ + + Sbjct: 62 SLTMLTRVNPEDASPQ----AICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDSFEKN 117 Query: 156 QEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEI-GFEDEMRQII 214 ++ +++ TPG +LD L K + +K ++DEAD +L+ G D+ ++ Sbjct: 118 KQI-----NAQVIVGTPGTVLD-LMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVK 171 Query: 215 KILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSD 274 + LP +D Q +LFSAT V A+ + P + +T+ D ++Q Y+ C ++ Sbjct: 172 RFLP-KDTQLVLFSATFADAVRQYAKKIV---PNANTLELQTNEVNVDAIKQLYMDCKNE 227 Query: 275 -KRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFF 333 +F +L I+F+++ + L V LHG + Q+R Sbjct: 228 ADKFDVLTELYGVMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLID 287 Query: 334 EFCNAERGILICTDVAARGLDIPAVDWIIQFDPPD------DPRDYIHRVGRTARGTKGK 387 +F +LI T+V ARG+DIP V ++ +D P DP YIHR+GRT R + K Sbjct: 288 DFREGRSKVLITTNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGR-K 346 Query: 388 GKSLMFL-TPNELGFLR-------YLKASKVPLNEYEFPENKIANV 425 G ++ F+ N L ++ ++VP ++++ E + V Sbjct: 347 GVAISFVHDKNSFNILSAIQKYFGDIEMTRVPTDDWDEVEKIVKKV 392 >5SUP-A nrPDB Length = 390 Score = 380 bits (977), Expect = e-106, Method: Composition-based stats. Identities = 117/385 (30%), Positives = 190/385 (49%), Gaps = 16/385 (4%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F++ L +AI GF + VQ TIP + G DVL AK+G GKT F++ ++ Sbjct: 8 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 67 Query: 104 LHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS-QTFGIVIGGANRRQEAEKLM 162 L + + ++VI RELA QI ++ + GG ++AE L Sbjct: 68 LDPVPGE----VAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLK 123 Query: 163 KG---VNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQIIKILP 218 ++++ATPGRL L K ++K +IDE D++LE + ++++I + P Sbjct: 124 NKDTAPHIVVATPGRL-KALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATP 182 Query: 219 NEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFL 278 D+Q M+FSAT + ++ + R L+ PL I V E T GL+Q Y+ + ++ Sbjct: 183 R-DKQVMMFSATLSQEIRPICRRFLQ-NPLEIFVDDEAK-LTLHGLQQYYIKLEEREKNR 239 Query: 279 LLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNA 338 L L + ++I+F+ S +LLN + P + +HG KQ++R + F + Sbjct: 240 KLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDF 299 Query: 339 ERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTAR-GTKGKGKSLMFLTPN 397 E+ I + TDV RG+DI ++ I +D ++ Y+HRVGR R GTKG S + + Sbjct: 300 EKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKED 359 Query: 398 ELGFLRYLKASKVPLNEYEFPENKI 422 E + + V + EFPE I Sbjct: 360 EEVLAKIQERFDVKIA--EFPEEGI 382 >3SQW-A nrPDB Length = 579 Score = 370 bits (949), Expect = e-102, Method: Composition-based stats. Identities = 150/432 (34%), Positives = 234/432 (54%), Gaps = 34/432 (7%) Query: 25 TSKQNNAAPE--GEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--R 80 +SK + E ++ T EE L + KAI +M F +T VQ +TI P+L+ Sbjct: 2 SSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDH 61 Query: 81 DVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVAREL--M 138 DV+ AKTG+GKT AFLIP + L + KF + +++ PTR+LALQI +++ M Sbjct: 62 DVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDM 121 Query: 139 EFHSQTFGIV--IGGANRRQEAEKLMK-GVNMLIATPGRLLDHLQNTKGFVFKNLKALII 195 + + + V +GG + R K+ K N++IATPGRL+D L+ F+ + ++ Sbjct: 122 NYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVL 181 Query: 196 DEADRILEIGFEDEMRQIIKILPNEDRQ------SMLFSATQTTKVEDLARISL-RPGPL 248 DEADR+LEIGF D++ I IL ++ + ++LFSAT KV+ LA + + L Sbjct: 182 DEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECL 241 Query: 249 FINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLK--------RNQKKKIIVFLSSCN 300 F++ V + + + ++Q V+ S+K +F+ ++ R+ K I+F + Sbjct: 242 FLDTVDKNEPEAHERIDQSVVI--SEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVK 299 Query: 301 SVKYYAELLNY---IDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPA 357 + +L DLP+LE HGK Q KRT+ F E GIL+CTDV ARG+D P Sbjct: 300 FTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPN 359 Query: 358 VDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASK----VPLN 413 V ++Q P + +YIHR+GRTAR K +G S++F+ +EL F+R L+ +K Sbjct: 360 VHEVLQIGVPSELANYIHRIGRTARSGK-EGSSVLFICKDELPFVRELEDAKNIVIAKQE 418 Query: 414 EYEFPENKIANV 425 +YE E + V Sbjct: 419 KYEPSEEIKSEV 430 >4W7S-A nrPDB Length = 463 Score = 358 bits (919), Expect = 3e-99, Method: Composition-based stats. Identities = 123/416 (29%), Positives = 215/416 (51%), Gaps = 33/416 (7%) Query: 31 AAPEGEQTTCVEKFEELKL-SQPTLKAI-EKMGFTTMTSVQARTIPPLL---AGRDVLGA 85 G + +EEL + + L+ I +++ F + T +Q TIP + RD LG Sbjct: 36 VTKGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGV 95 Query: 86 AKTGSGKTLAFLIPAIELLHSLKFKPR-----NGTGIIVITPTRELALQIFGVARELMEF 140 A TGSGKTLAF+IP + + +P +G +++ PTREL QI +++ + Sbjct: 96 ASTGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKI 155 Query: 141 HSQ------TFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALI 194 S+ ++GG + + + L +G ++L+ATPGRL+D L+N V K ++ L+ Sbjct: 156 WSKESNYDCKVISIVGGHSLEEISFSLSEGCDILVATPGRLIDSLEN-HLLVMKQVETLV 214 Query: 195 IDEADRILEIGFEDEMRQIIKIL-----PNEDRQSMLFSATQTTKVEDLARISLRPGPLF 249 +DEAD+++++GFED++ I+ + +RQ+++F+AT T +E +A ++ P++ Sbjct: 215 LDEADKMIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQK-PVY 273 Query: 250 INVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELL 309 + ET + ++Q D+D+ + II+F++ + + AE Sbjct: 274 ATIGVETGSEPL--IQQVVEYADNDEDKFKKLKPIVAKYDPPIIIFINYKQTADWLAEKF 331 Query: 310 NYI-DLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPD 368 ++ V LHG + Q++R ++ F + I+I T+VAARGLDIP V ++ F Sbjct: 332 QKETNMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISK 391 Query: 369 DPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFL-----RYLKASKVPLNEYEFPE 419 DYIHR+GRT R +G ++ F++ E L +Y++ PLN F E Sbjct: 392 KMDDYIHRIGRTGRAA-NEGTAVSFVSAAEDESLIRELYKYVRKHD-PLNSNIFSE 445 >5ZWN-y nrPDB Length = 588 Score = 357 bits (917), Expect = 5e-99, Method: Composition-based stats. Identities = 123/416 (29%), Positives = 215/416 (51%), Gaps = 33/416 (7%) Query: 31 AAPEGEQTTCVEKFEELKL-SQPTLKAI-EKMGFTTMTSVQARTIPPLL---AGRDVLGA 85 G + +EEL + + L+ I +++ F + T +Q TIP + RD LG Sbjct: 161 VTKGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGV 220 Query: 86 AKTGSGKTLAFLIPAIELLHSLKFKPR-----NGTGIIVITPTRELALQIFGVARELMEF 140 A TGSGKTLAF+IP + + +P +G +++ PTREL QI +++ + Sbjct: 221 ASTGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKI 280 Query: 141 HSQ------TFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALI 194 S+ ++GG + + + L +G ++L+ATPGRL+D L+N V K ++ L+ Sbjct: 281 WSKESNYDCKVISIVGGHSLEEISFSLSEGCDILVATPGRLIDSLEN-HLLVMKQVETLV 339 Query: 195 IDEADRILEIGFEDEMRQIIKIL-----PNEDRQSMLFSATQTTKVEDLARISLRPGPLF 249 +DEAD+++++GFED++ I+ + +RQ+++F+AT T +E +A ++ P++ Sbjct: 340 LDEADKMIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQK-PVY 398 Query: 250 INVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELL 309 + ET + ++Q D+D+ + II+F++ + + AE Sbjct: 399 ATIGVETGSEPL--IQQVVEYADNDEDKFKKLKPIVAKYDPPIIIFINYKQTADWLAEKF 456 Query: 310 NYI-DLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPD 368 ++ V LHG + Q++R ++ F + I+I T+VAARGLDIP V ++ F Sbjct: 457 QKETNMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISK 516 Query: 369 DPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFL-----RYLKASKVPLNEYEFPE 419 DYIHR+GRT R +G ++ F++ E L +Y++ PLN F E Sbjct: 517 KMDDYIHRIGRTGRAA-NEGTAVSFVSAAEDESLIRELYKYVRKHD-PLNSNIFSE 570 >4KBG-A nrPDB Length = 365 Score = 353 bits (905), Expect = 1e-97, Method: Composition-based stats. Identities = 110/333 (33%), Positives = 170/333 (51%), Gaps = 10/333 (3%) Query: 43 KFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE 102 +F++ L L+A+ G TT T +QA +P L G+D++G A+TG+GKTLAF +P E Sbjct: 2 EFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAE 61 Query: 103 LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLM 162 L + + R +V+TPTRELALQ+ + V GG ++ E L+ Sbjct: 62 RLAPSQERGRK-PRALVLTPTRELALQVASELTAVAPH--LKVVAVYGGTGYGKQKEALL 118 Query: 163 KGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDR 222 +G + ++ATPGR LD+L ++ ++DEAD +L +GFE+E+ ++ P R Sbjct: 119 RGADAVVATPGRALDYL-RQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATP-PSR 176 Query: 223 QSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFS 282 Q++LFSAT + + LA + P+ INV+ + + E+ V R +L Sbjct: 177 QTLLFSATLPSWAKRLAERYM-KNPVLINVIKDEPVTY----EEEAVPAPVRGRLEVLSD 231 Query: 283 FLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGI 342 L + +VF + + A+ L + P LHG Q +R F E + Sbjct: 232 LLYVASPDRAMVFTRTKAETEEIAQGLLRLGHPAQALHGDLSQGERERVLGAFRQGEVRV 291 Query: 343 LICTDVAARGLDIPAVDWIIQFDPPDDPRDYIH 375 L+ TDVAARGLDIP VD ++ + PD Y H Sbjct: 292 LVATDVAARGLDIPQVDLVVHYRLPDRAEAYQH 324 >4LJY-A nrPDB Length = 493 Score = 350 bits (898), Expect = 9e-97, Method: Composition-based stats. Identities = 122/427 (28%), Positives = 213/427 (49%), Gaps = 32/427 (7%) Query: 9 SRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAI-EKMGFTTMTS 67 S S E V+E S N V K+ +L LS T+ I EK+ F ++T Sbjct: 17 SETVSSMSEMEVEELRLSLDNIKIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSLTP 76 Query: 68 VQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRN--GTGIIVITPTRE 125 +Q++ +P +++GRDV+G +KTGSGKT+++L+P + + + + ++ G +++ PTRE Sbjct: 77 IQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGLILAPTRE 136 Query: 126 LALQIFGVARELMEF-HSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ--NT 182 LALQI + E S GG+ +++ L +G +++ATPGR +D L + Sbjct: 137 LALQIHEEVTKFTEADTSIRSVCCTGGSEMKKQITDLKRGTEIVVATPGRFIDILTLNDG 196 Query: 183 KGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARIS 242 K K + +++DEADR+ ++GFE ++ QI+K + D+Q +LFSAT K+ A Sbjct: 197 KLLSTKRITFVVMDEADRLFDLGFEPQITQIMKTV-RPDKQCVLFSATFPNKLRSFAVRV 255 Query: 243 LRPGPLFINVVPETDNSTADGLEQGYVVCDS-DKRFLLLFSFLKRNQ------------- 288 L I++ + + ++Q + +C S D++F L + Sbjct: 256 LHSP---ISITINSKGMVNENVKQKFRICHSEDEKFDNLVQLIHERSEFFDEVQSENDGQ 312 Query: 289 -------KKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERG 341 K I+F+SS N + ++ L + +H + Q+R +F + Sbjct: 313 SSDVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKPYQERLMNLEKFKREKNS 372 Query: 342 ILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGF 401 IL+CT+V +RGL++P V +I ++ Y+H GRTARG++ G ++ L +EL Sbjct: 373 ILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRS-GTAITLLLHDELSG 431 Query: 402 LRYLKAS 408 L + Sbjct: 432 AYILSKA 438 >6CRM-A nrPDB Length = 541 Score = 343 bits (879), Expect = 1e-94, Method: Composition-based stats. Identities = 93/422 (22%), Positives = 169/422 (40%), Gaps = 44/422 (10%) Query: 33 PEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGK 92 P G E + + L++ L+ E G+ QA I +L GRD L TG GK Sbjct: 16 PRGSHMAQAEVYSQETLAKQVLQ--ETFGYQQFRPGQATIIDAVLEGRDCLVVMPTGGGK 73 Query: 93 TLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGA 152 +L + IPA+ + G IV++P L + Sbjct: 74 SLCYQIPAL---------VKTGL-TIVVSPLISLMKDQVDQLLANG-----VAAACLNST 118 Query: 153 NRRQEAEKLMKGVN-----MLIATPGRLL-DHLQNTKGFVFKNLKALIIDEADRILEIG- 205 R+E + ++ G +L P RL+ D+ +T G+ +L + +DEA I + G Sbjct: 119 QSREEQQAVLAGCRTGQVRLLYIAPERLMMDNFIDTLGY--WDLAMVAVDEAHCISQWGH 176 Query: 206 -FEDEMR---QIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTA 261 F E Q+ P ++ +A TT+ D+ R+ PL + S+ Sbjct: 177 DFRPEYAALGQLRARFPAVPFMALTATADDTTR-RDIVRLLGLDDPLI-------EISSF 228 Query: 262 DGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHG 321 D Y++ + K L +++ + K I++ +S V+ A L + H Sbjct: 229 DRPNIRYMLMEKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSRGISAAAYHA 288 Query: 322 KQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTA 381 + + R + +F + I++ T G++ P V +++ FD P + Y GR Sbjct: 289 GLEHEVRASVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAG 348 Query: 382 RGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPENKI----ANVQSQ-LEKLIKSN 436 R ++++F P ++ +LR K P + +K+ A ++Q +L+ N Sbjct: 349 RDGL-PAEAMLFYDPADMAWLRRCLEEKAPGPLQDIERHKLNAMGAFAEAQTCRRLVLLN 407 Query: 437 YY 438 Y+ Sbjct: 408 YF 409 >3FHO-A nrPDB Length = 508 Score = 339 bits (869), Expect = 2e-93, Method: Composition-based stats. Identities = 97/376 (25%), Positives = 185/376 (49%), Gaps = 31/376 (8%) Query: 67 SVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTR 124 +Q + +P LL+ R+++G +++G+GKT AF + + + + KP+ I + P+R Sbjct: 144 KIQEKALPLLLSNPPRNMIGQSQSGTGKTAAFALTMLSRVDASVPKPQ----AICLAPSR 199 Query: 125 ELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKG 184 ELA QI V E+ ++ G + + K+ ++I TPG ++D L + Sbjct: 200 ELARQIMDVVTEMGKYTEVKTA--FGIKDSVPKGAKID--AQIVIGTPGTVMD-LMKRRQ 254 Query: 185 FVFKNLKALIIDEADRILEI-GFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISL 243 +++K ++DEAD +L+ G D+ +I +LP + Q +LFSAT + +VE A Sbjct: 255 LDARDIKVFVLDEADNMLDQQGLGDQSMRIKHLLPR-NTQIVLFSATFSERVEKYAERF- 312 Query: 244 RPGPLFINVVPETDNSTADGLEQGYVVCDSDK-RFLLLFSFLKRNQKKKIIVFLSSCNSV 302 P + +T+ + +G++Q Y+ C S++ ++ +L + I+F ++ Sbjct: 313 --APNANEIRLKTEELSVEGIKQLYMDCQSEEHKYNVLVELYGLLTIGQSIIFCKKKDTA 370 Query: 303 KYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWII 362 + A + V L G + +R F +L+ T+V ARG+D+ V+ ++ Sbjct: 371 EEIARRMTADGHTVACLTGNLEGAQRDAIMDSFRVGTSKVLVTTNVIARGIDVSQVNLVV 430 Query: 363 QFDPP------DDPRDYIHRVGRTARGTKGKGKSLMFL----TPNELGFLRYLKA---SK 409 +D P DP+ Y+HR+GRT R + G S+ F+ + E+ ++ ++ Sbjct: 431 NYDMPLDQAGRPDPQTYLHRIGRTGRFGR-VGVSINFVHDKKSWEEMNAIQEYFQRPITR 489 Query: 410 VPLNEYEFPENKIANV 425 VP ++YE E + N Sbjct: 490 VPTDDYEELEKVVKNA 505 >2Z0M-A nrPDB Length = 337 Score = 336 bits (861), Expect = 2e-92, Method: Composition-based stats. Identities = 118/350 (33%), Positives = 182/350 (52%), Gaps = 28/350 (8%) Query: 49 LSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLK 108 +++ +AI +MGF T VQ++TIP +L G++V+ AKTGSGKT A+ IP +EL Sbjct: 1 MNEKIEQAIREMGFKNFTEVQSKTIPLMLQGKNVVVRAKTGSGKTAAYAIPILEL----- 55 Query: 109 FKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNML 168 G +V+TPTREL Q+ R++ + V GG + + ++ + +++ Sbjct: 56 -----GMKSLVVTPTRELTRQVASHIRDIGRYMDTKVAEVYGGMPYKAQINRV-RNADIV 109 Query: 169 IATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFS 228 +ATPGRLLD + + +IIDEAD + E+GF D+++ I+ N + + LFS Sbjct: 110 VATPGRLLDLWSKG-VIDLSSFEIVIIDEADLMFEMGFIDDIKIILAQTSNR-KITGLFS 167 Query: 229 ATQTTKVEDLARISLRPGPLFINVVPETDNST-ADGLEQGYVVCDSDKRFLLLFSFLKRN 287 AT ++ + + FI E + +E +V D R + L+ N Sbjct: 168 ATIPEEIRKVVK-------DFITNYEEIEACIGLANVEHKFVHVKDDWRSKV--QALREN 218 Query: 288 QKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTD 347 + K +IVF+ + N V L + +EL G Q R F E +LI TD Sbjct: 219 KDKGVIVFVRTRNRVAKLVRLFDN----AIELRGDLPQSVRNRNIDAFREGEYDMLITTD 274 Query: 348 VAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPN 397 VA+RGLDIP V+ +I FD P D R YIHR+GRT R + KG+++ F+ Sbjct: 275 VASRGLDIPLVEKVINFDAPQDLRTYIHRIGRTGRMGR-KGEAITFILNE 323 >1OYY-A nrPDB Length = 523 Score = 316 bits (811), Expect = 1e-86, Method: Composition-based stats. Identities = 87/406 (21%), Positives = 162/406 (39%), Gaps = 46/406 (11%) Query: 50 SQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKF 109 ++ L+ E G+ Q I +L+GRD L TG GK+L + IPA+ LL+ L Sbjct: 13 AKQVLQ--ETFGYQQFRPGQEEIIDTVLSGRDCLVVMPTGGGKSLCYQIPAL-LLNGL-- 67 Query: 110 KPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVN--- 166 +V++P L + + R++ ++M G Sbjct: 68 -------TVVVSPLISLMKDQVDQLQANG-----VAAACLNSTQTREQQLEVMTGCRTGQ 115 Query: 167 --MLIATPGRLL--DHLQNTKGFVFKNLKALIIDEADRILEIG--FEDEMR---QIIKIL 217 +L P RL+ + L++ N L +DEA I + G F E Q+ + Sbjct: 116 IRLLYIAPERLMLDNFLEH---LAHWNPVLLAVDEAHCISQWGHDFRPEYAALGQLRQRF 172 Query: 218 PNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRF 277 P ++ +A TT+ +D+ R+ PL S+ D Y++ + K Sbjct: 173 PTLPFMALTATADDTTR-QDIVRLLGLNDPLI-------QISSFDRPNIRYMLMEKFKPL 224 Query: 278 LLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCN 337 L +++ + K I++ +S V+ A L + H + R + +F Sbjct: 225 DQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQR 284 Query: 338 AERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPN 397 + I++ T G++ P V +++ FD P + Y GR R ++++F P Sbjct: 285 DDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGL-PAEAMLFYDPA 343 Query: 398 ELGFLRYLKASKVPLNEYEFPENKI----ANVQSQ-LEKLIKSNYY 438 ++ +LR K + +K+ A ++Q +L+ NY+ Sbjct: 344 DMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYF 389 >4Q48-A nrPDB Length = 525 Score = 276 bits (705), Expect = 2e-74, Method: Composition-based stats. Identities = 82/399 (20%), Positives = 149/399 (37%), Gaps = 34/399 (8%) Query: 52 PTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKP 111 L+ I G+ VQ + + G + L TG GK+L + +P++ Sbjct: 14 HLLQTI--WGYPAFRGVQGEIVQQVAEGGNALVLMPTGGGKSLCYQLPSLL--------- 62 Query: 112 RNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKG-VNMLIA 170 R GTG IV++P L R+ + + R+ + L++G +++L Sbjct: 63 RPGTG-IVVSPLIALMKDQVDTLRQ-NGVRAAFLNSTLLPHEAREVEDALLRGDLDLLYV 120 Query: 171 TPGRLLDHLQNTKGFVFK-NLKALIIDEADRILEIG--FEDEMRQII---KILPNEDRQS 224 P RLL + T + + + IDEA + + G F E +Q+ + P R + Sbjct: 121 APERLL--MPRTLDLLERAPVALFAIDEAHCVSQWGHDFRPEYQQLSVLAERFPELPRVA 178 Query: 225 MLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFL 284 + +A + T+ + + + L P F++ + Q V + LL Sbjct: 179 LTATADERTRADIKSVLRLEDAPQFVSSFDRPNI-------QYRVGLKDSPKTQLLHFIR 231 Query: 285 KRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILI 344 + + IV+ S SV+ A+ L + L H +R N F N E I+ Sbjct: 232 EEHPGDAGIVYCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLNEEGVIVC 291 Query: 345 CTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRY 404 T G+D P V ++ D P Y GR R +++ + + R Sbjct: 292 ATVAFGMGIDKPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTAWMVYGLSDVVNVRRM 351 Query: 405 LKASKVPLNEYEFPENKIANV-----QSQLEKLIKSNYY 438 L S P +K+ + + + + +Y+ Sbjct: 352 LAQSDAPEEVKRVEASKLDALLTYCEAATCRRQVLLHYF 390 >1WRB-A nrPDB Length = 253 Score = 273 bits (698), Expect = 1e-73, Method: Composition-based stats. Identities = 81/255 (31%), Positives = 138/255 (54%), Gaps = 12/255 (4%) Query: 20 VDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG 79 D+ + + P+ T +E F+ELKL I + T +Q IP +L Sbjct: 1 FDKYDSIPVSVTGPDYSATNVIENFDELKLDPTIRNNILLASYQRPTPIQKNAIPAILEH 60 Query: 80 RDVLGAAKTGSGKTLAFLIPAIEL-----LHSLKFKPRNGTGIIVITPTRELALQIFGVA 134 RD++ A+TGSGKT AFLIP I L+ ++ +++ PTRELA+QI + Sbjct: 61 RDIMACAQTGSGKTAAFLIPIINHLVCQDLNQQRYSKTAYPKCLILAPTRELAIQILSES 120 Query: 135 RELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALI 194 ++ +V GGA+ + ++ G ++L+ATPGRL+D ++ K + K ++ Sbjct: 121 QKFSLNTPLRSCVVYGGADTHSQIREVQMGCHLLVATPGRLVDFIEKNK-ISLEFCKYIV 179 Query: 195 IDEADRILEIGFEDEMRQII--KILPNE-DRQSMLFSATQTTKVEDLARISLRPGPLFIN 251 +DEADR+L++GFE ++R+II +P+ +RQ+++FSAT +++ LA L +I Sbjct: 180 LDEADRMLDMGFEPQIRKIIEESNMPSGINRQTLMFSATFPKEIQKLAADFL---YNYIF 236 Query: 252 VVPETDNSTADGLEQ 266 + ST+D ++Q Sbjct: 237 MTVGRVGSTSDSIKQ 251 >3LY5-A nrPDB Length = 262 Score = 263 bits (672), Expect = 1e-70, Method: Composition-based stats. Identities = 137/244 (56%), Positives = 186/244 (76%), Gaps = 4/244 (1%) Query: 10 RDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELK--LSQPTLKAIEKMGFTTMTS 67 + + E+P DE S+ + F L +++ TLKAI++MGFT MT Sbjct: 21 QSMNNVEKPDNDEDE-SEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTE 79 Query: 68 VQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELA 127 +Q ++I PLL GRD+L AAKTGSGKTLAFLIPA+EL+ L+F PRNGTG+++++PTRELA Sbjct: 80 IQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTRELA 139 Query: 128 LQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVF 187 +Q FGV +ELM H T+G+++GG+NR EA+KL G+N+++ATPGRLLDH+QNT GF++ Sbjct: 140 MQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFMY 199 Query: 188 KNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGP 247 KNL+ L+IDEADRIL++GFE+E++QIIK+LP RQ+MLFSATQT KVEDLARISL+ P Sbjct: 200 KNLQCLVIDEADRILDVGFEEELKQIIKLLPTR-RQTMLFSATQTRKVEDLARISLKKEP 258 Query: 248 LFIN 251 L++ Sbjct: 259 LYVG 262 >5LST-A nrPDB Length = 693 Score = 263 bits (671), Expect = 2e-70, Method: Composition-based stats. Identities = 79/381 (20%), Positives = 136/381 (35%), Gaps = 37/381 (9%) Query: 50 SQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKF 109 +A+E++G Q R + +L+G L TG+GK+L + +PA+ + Sbjct: 43 PAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPAL------LY 96 Query: 110 KPRNGTGIIVITPTRELAL-QIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMK----G 164 R+ +V++P L Q+ G+ L + G R+Q L K Sbjct: 97 SRRSPCLTLVVSPLLSLMDDQVSGLPPCL------KAACIHSGMTRKQRESVLQKIRAAQ 150 Query: 165 VNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIG--FEDEMRQIIKILPNEDR 222 V++L+ TP L+ + IDEA + + F ++ K+L E Sbjct: 151 VHVLMLTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVL-RERM 209 Query: 223 QSMLF-----SATQTTKVEDLARISLRPGPLFINVVPETDN-----STADGLEQGYVVCD 272 F +AT+ T + +++ P P N S +Q + Sbjct: 210 GVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLL 269 Query: 273 SDKRFLLLFSFL----KRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVL-ELHGKQKQQK 327 KRF L S + +R ++I L +C + H ++ Sbjct: 270 QGKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRE 329 Query: 328 RTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGK 387 R F + +++ T GLD P V ++ P Y+ VGR R + Sbjct: 330 RRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQ-P 388 Query: 388 GKSLMFLTPNELGFLRYLKAS 408 +FL P LR L+ Sbjct: 389 AHCHLFLQPQGED-LRELRRH 408 >3BOR-A nrPDB Length = 237 Score = 262 bits (669), Expect = 3e-70, Method: Composition-based stats. Identities = 76/223 (34%), Positives = 120/223 (53%), Gaps = 8/223 (3%) Query: 34 EGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKT 93 E V+ F+++ L + L+ I GF +++Q R I P + G DV+ A++G+GKT Sbjct: 22 ESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKT 81 Query: 94 LAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGAN 153 F I ++ L + T +V+ PTRELA QI V L ++ T IGG N Sbjct: 82 ATFAISILQQLEIEFKE----TQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTN 137 Query: 154 RRQEAEKLM-KGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQ 212 R E +KL + ++++ TPGR+ D L N + K +K ++DEAD +L GF+D++ + Sbjct: 138 VRNEMQKLQAEAPHIVVGTPGRVFDML-NRRYLSPKWIKMFVLDEADEMLSRGFKDQIYE 196 Query: 213 IIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPE 255 I + L N Q +L SAT T V ++ + +R P+ I V E Sbjct: 197 IFQKL-NTSIQVVLLSATMPTDVLEVTKKFMR-DPIRILVKKE 237 >5ZBZ-A nrPDB Length = 220 Score = 259 bits (663), Expect = 1e-69, Method: Composition-based stats. Identities = 74/221 (33%), Positives = 120/221 (54%), Gaps = 8/221 (3%) Query: 34 EGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKT 93 E V+ F+++ LS+ L+ I GF +++Q R I P + G DV+ A++G+GKT Sbjct: 6 ESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKT 65 Query: 94 LAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGAN 153 F I ++ + T +V+ PTRELA QI V L ++ + IGG N Sbjct: 66 ATFAISILQQIELDLK----ATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 121 Query: 154 RRQEAEKL-MKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQ 212 R E +KL M+ ++++ TPGR+ D L N + K +K ++DEAD +L GF+D++ Sbjct: 122 VRAEVQKLQMEAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYD 180 Query: 213 IIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVV 253 I + L N + Q +L SAT + V ++ + +R P+ I V Sbjct: 181 IFQKL-NSNTQVVLLSATMPSDVLEVTKKFMR-DPIRILVK 219 >4PX9-A nrPDB Length = 292 Score = 258 bits (659), Expect = 5e-69, Method: Composition-based stats. Identities = 81/234 (34%), Positives = 128/234 (54%), Gaps = 24/234 (10%) Query: 29 NNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKT 88 NN P +E F ++++ + + IE +T T VQ IP + RD++ A+T Sbjct: 58 NNCPPH------IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQT 111 Query: 89 GSGKTLAFLIPAIEL---------LHSLKFKPRNG-----TGIIVITPTRELALQIFGVA 134 GSGKT AFL+P + L ++K R G +V+ PTRELA+QI+ A Sbjct: 112 GSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEA 171 Query: 135 RELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALI 194 R+ +V GGA+ Q+ L +G ++L+ATPGRL+D ++ K K L+ Sbjct: 172 RKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLV 230 Query: 195 IDEADRILEIGFEDEMRQIIK---ILPNEDRQSMLFSATQTTKVEDLARISLRP 245 +DEADR+L++GFE ++R+I++ + P R +M+FSAT +++ LAR L Sbjct: 231 LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDE 284 >3FE2-A nrPDB Length = 242 Score = 251 bits (641), Expect = 5e-67, Method: Composition-based stats. Identities = 82/237 (34%), Positives = 130/237 (54%), Gaps = 9/237 (3%) Query: 10 RDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQ 69 R ++ E ++ T + +N V F E + I + FT T++Q Sbjct: 3 RTAQEVETYRRSKEITVRGHNCPKP------VLNFYEANFPANVMDVIARQNFTEPTAIQ 56 Query: 70 ARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPR-NGTGIIVITPTRELAL 128 A+ P L+G D++G A+TGSGKTL++L+PAI ++ F R +G +V+ PTRELA Sbjct: 57 AQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQ 116 Query: 129 QIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFK 188 Q+ VA E + GGA + + L +GV + IATPGRL+D L+ K + Sbjct: 117 QVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKT-NLR 175 Query: 189 NLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRP 245 L++DEADR+L++GFE ++R+I+ + DRQ++++SAT +V LA L+ Sbjct: 176 RTTYLVLDEADRMLDMGFEPQIRKIVDQI-RPDRQTLMWSATWPKEVRQLAEDFLKD 231 >5H1Y-A nrPDB Length = 281 Score = 241 bits (616), Expect = 4e-64, Method: Composition-based stats. Identities = 85/235 (36%), Positives = 134/235 (57%), Gaps = 14/235 (5%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 ++ F+E+K L+ ++K G T +Q + IP +L+GRD++G A TGSGKTL F +P Sbjct: 51 IKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPV 110 Query: 101 ----IELLHSLKFKPRNGTGIIVITPTRELALQIFGV----ARELMEFHS--QTFGIVIG 150 +E L F R G ++I P+RELA Q G+ R L E S + IG Sbjct: 111 IMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIG 170 Query: 151 GANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEM 210 G + +++ E + GV+M++ATPGRL+D LQ K + L +DEADR++++GFE ++ Sbjct: 171 GMSVKEQMETIRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFEGDI 229 Query: 211 RQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLE 265 R I RQ++LFSAT K+++ A+ +L P+ INV ++ D ++ Sbjct: 230 RTIFSYF-KGQRQTLLFSATMPKKIQNFAKSALVK-PVTINVG-RAGAASLDVIQ 281 >6AIC-A nrPDB Length = 214 Score = 241 bits (615), Expect = 6e-64, Method: Composition-based stats. Identities = 79/213 (37%), Positives = 121/213 (56%), Gaps = 7/213 (3%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 ++ F+EL +S T++++E MGF T +Q +IP L G D+LG A+TG+GKT AF IP Sbjct: 1 MQNFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPL 60 Query: 101 IELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEK 160 IE K + G +++ PTRELA+Q+ RE V GG ++ + Sbjct: 61 IE-----KVVGKQGVQSLILAPTRELAMQVAEQLREFSRGQGVQVVTVFGGMPIERQIKA 115 Query: 161 LMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNE 220 L KG +++ TPGR++DHL N + + LI+DEAD ++ +GF D+MR I+ +P Sbjct: 116 LKKGPQIVVGTPGRVIDHL-NRRTLKTDGIHTLILDEADEMMNMGFIDDMRFIMDKIPAV 174 Query: 221 DRQSMLFSATQTTKVEDLARISLRPGPLFINVV 253 RQ+MLFSAT ++ L + + P I + Sbjct: 175 QRQTMLFSATMPKAIQALVQQFM-KSPKIIKTM 206 >5GVS-A nrPDB Length = 231 Score = 241 bits (614), Expect = 8e-64, Method: Composition-based stats. Identities = 84/222 (37%), Positives = 129/222 (58%), Gaps = 13/222 (5%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPA 100 ++ F+E+K L+ ++K G T +Q + IP +L+GRD++G A TGSGKTL F +P Sbjct: 12 IKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPV 71 Query: 101 ----IELLHSLKFKPRNGTGIIVITPTRELALQIFGV----ARELMEFHS--QTFGIVIG 150 +E L F R G ++I P+RELA Q G+ R L E S + IG Sbjct: 72 IMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIG 131 Query: 151 GANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEM 210 G + +++ E + GV+M++ATPGRL+D LQ K + L +DEADR++++GFE ++ Sbjct: 132 GMSVKEQMETIRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFEGDI 190 Query: 211 RQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINV 252 R I RQ++LFSAT K+++ A+ +L P+ INV Sbjct: 191 RTIFSYF-KGQRQTLLFSATMPKKIQNFAKSALVK-PVTINV 230 >2PL3-A nrPDB Length = 236 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 100/223 (44%), Positives = 152/223 (68%), Gaps = 3/223 (1%) Query: 34 EGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKT 93 E + +F + LS+ TLK +++ + +T +Q +TI L G+DVLGAAKTGSGKT Sbjct: 17 EKINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKT 76 Query: 94 LAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGAN 153 LAFL+P +E L+ L++ +G G+++I+PTRELA Q F V R++ + H + G++IGG + Sbjct: 77 LAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKD 136 Query: 154 RRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQI 213 + EAE++ +N+L+ TPGRLL H+ T F +L+ L++DEADRIL++GF D M + Sbjct: 137 LKHEAERI-NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAV 195 Query: 214 IKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPET 256 I+ LP + RQ++LFSATQT V+DLAR+SL P ++ V + Sbjct: 196 IENLPKK-RQTLLFSATQTKSVKDLARLSL-KNPEYVWVHEKA 236 >1QVA-A nrPDB Length = 223 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 71/219 (32%), Positives = 119/219 (54%), Gaps = 8/219 (3%) Query: 34 EGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKT 93 + V KF++++L + L+ + GF +++Q R I P++ G DVL A++G+GKT Sbjct: 13 QTNYQKVVYKFDDMELDEQLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKT 72 Query: 94 LAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGAN 153 F I A++ + + P+ +++ PTRELALQI V L IGG + Sbjct: 73 GTFSIAALQRIDTSVKAPQ----ALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTS 128 Query: 154 RRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQI 213 ++AE L + +++ TPGR+ D++Q + F +K I+DEAD +L GF++++ QI Sbjct: 129 FVEDAEGL-RDAQIVVGTPGRVFDNIQRRR-FRTDKIKMFILDEADEMLSSGFKEQIYQI 186 Query: 214 IKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINV 252 +LP Q +L SAT V ++ +R P+ I V Sbjct: 187 FTLLP-PTTQVVLLSATMPNDVLEVTTKFMR-NPVRILV 223 >3BER-A nrPDB Length = 249 Score = 237 bits (606), Expect = 7e-63, Method: Composition-based stats. Identities = 87/227 (38%), Positives = 139/227 (61%), Gaps = 9/227 (3%) Query: 23 KSTSKQNNAAPEGEQ----TTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLA 78 + +++++ E Q + F++L ++ +A +++G+T T +Q IP L Sbjct: 20 FQSMEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 79 Query: 79 GRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELM 138 GRD++G A+TGSGKT AF +P + ++L P+ +V+TPTRELA QI L Sbjct: 80 GRDIIGLAETGSGKTGAFALPIL---NALLETPQRLF-ALVLTPTRELAFQISEQFEALG 135 Query: 139 EFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEA 198 +++GG + ++ L K +++IATPGRL+DHL+NTKGF + LK L++DEA Sbjct: 136 SSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEA 195 Query: 199 DRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRP 245 DRIL + FE E+ +I+K++P DR++ LFSAT T KV+ L R +L+ Sbjct: 196 DRILNMDFETEVDKILKVIPR-DRKTFLFSATMTKKVQKLQRAALKN 241 >5GJU-A nrPDB Length = 205 Score = 237 bits (605), Expect = 8e-63, Method: Composition-based stats. Identities = 73/212 (34%), Positives = 113/212 (53%), Gaps = 8/212 (3%) Query: 42 EKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAI 101 F +L L P L+A+ +G+ + +QA IP LL GRDVLG A+TGSGKT AF +P + Sbjct: 1 TTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLL 60 Query: 102 ELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFH-SQTFGIVIGGANRRQEAEK 160 + L P+ I+V+ PTRELA+Q+ + + + GG + Sbjct: 61 QNLDPELKAPQ----ILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQLRA 116 Query: 161 LMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNE 220 L +G +++ TPGRLLDHL+ L L++DEAD +L +GF +++ I+ +P E Sbjct: 117 LRQGPQIVVGTPGRLLDHLKRG-TLDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIP-E 174 Query: 221 DRQSMLFSATQTTKVEDLARISLRPGPLFINV 252 Q+ LFSAT + + R + P + + Sbjct: 175 GHQTALFSATMPEAIRRITRRFM-KEPQEVRI 205 >2GXQ-A nrPDB Length = 207 Score = 236 bits (602), Expect = 2e-62, Method: Composition-based stats. Identities = 75/211 (35%), Positives = 119/211 (56%), Gaps = 6/211 (2%) Query: 43 KFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE 102 +F++ L L+A+ G TT T +QA +P L G+D++G A+TG+GKTLAF +P E Sbjct: 2 EFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAE 61 Query: 103 LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLM 162 L + + R +V+TPTRELALQ+ + V GG ++ E L+ Sbjct: 62 RLAPSQERGRK-PRALVLTPTRELALQVASELTAVAPH--LKVVAVYGGTGYGKQKEALL 118 Query: 163 KGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDR 222 +G + ++ATPGR LD+L ++ ++DEAD +L +GFE+E+ ++ P R Sbjct: 119 RGADAVVATPGRALDYL-RQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATP-PSR 176 Query: 223 QSMLFSATQTTKVEDLARISLRPGPLFINVV 253 Q++LFSAT + + LA + P+ INV+ Sbjct: 177 QTLLFSATLPSWAKRLAERYM-KNPVLINVI 206 >1VEC-A nrPDB Length = 206 Score = 235 bits (600), Expect = 3e-62, Method: Composition-based stats. Identities = 72/210 (34%), Positives = 115/210 (54%), Gaps = 8/210 (3%) Query: 43 KFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE 102 +FE+ L + L I +MG+ + +Q +IP L+GRD+L AK G+GK+ A+LIP +E Sbjct: 4 EFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLE 63 Query: 103 LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFH-SQTFGIVIGGANRRQEAEKL 161 L ++ +VI PTRELALQ+ + ++ + GG N R + +L Sbjct: 64 RLD----LKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRL 119 Query: 162 MKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNED 221 V+++IATPGR+LD ++ +++ +++DEAD++L F M II LP ++ Sbjct: 120 DDTVHVVIATPGRILDLIKKGVAK-VDHVQMIVLDEADKLLSQDFVQIMEDIILTLP-KN 177 Query: 222 RQSMLFSATQTTKVEDLARISLRPGPLFIN 251 RQ +L+SAT V+ L P IN Sbjct: 178 RQILLYSATFPLSVQKFMNSHLEK-PYEIN 206 >1T6N-A nrPDB Length = 220 Score = 232 bits (592), Expect = 3e-61, Method: Composition-based stats. Identities = 64/212 (30%), Positives = 111/212 (52%), Gaps = 10/212 (4%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 F + L L+AI GF + VQ IP + G DVL AK+G GKT F++ ++ Sbjct: 16 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 75 Query: 104 LHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS-QTFGIVIGGANRRQEAEKLM 162 L + + ++V+ TRELA QI ++ + GG + +++ E L Sbjct: 76 LEPVTGQ----VSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLK 131 Query: 163 KGV-NMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEI-GFEDEMRQIIKILPNE 220 K ++++ TPGR+L L K K++K I+DE D++LE ++++I ++ P+E Sbjct: 132 KNCPHIVVGTPGRIL-ALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHE 190 Query: 221 DRQSMLFSATQTTKVEDLARISLRPGPLFINV 252 +Q M+FSAT + ++ + R ++ P+ I V Sbjct: 191 -KQVMMFSATLSKEIRPVCRKFMQ-DPMEIFV 220 >3IUY-A nrPDB Length = 228 Score = 229 bits (585), Expect = 2e-60, Method: Composition-based stats. Identities = 75/213 (35%), Positives = 124/213 (58%), Gaps = 9/213 (4%) Query: 42 EKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAI 101 + F++ LK+I ++G T +Q++ P +L G D++ A+TG+GKTL++L+P Sbjct: 23 DAFQQY---PDLLKSIIRVGILKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGF 79 Query: 102 ELLH--SLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAE 159 L + + RNG G++V+TPTRELAL + + + + GG NR + E Sbjct: 80 IHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYS-YKGLKSICIYGGRNRNGQIE 138 Query: 160 KLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPN 219 + KGV+++IATPGRL D LQ +++ L+IDEAD++L++ FE ++R+I+ + Sbjct: 139 DISKGVDIIIATPGRLND-LQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDV-R 196 Query: 220 EDRQSMLFSATQTTKVEDLARISLRPGPLFINV 252 DRQ+++ SAT V LA L P+ + V Sbjct: 197 PDRQTVMTSATWPDTVRQLALSYL-KDPMIVYV 228 >3FHC-B nrPDB Length = 235 Score = 228 bits (582), Expect = 4e-60, Method: Composition-based stats. Identities = 62/220 (28%), Positives = 115/220 (52%), Gaps = 11/220 (5%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLI 98 V+ FEEL+L L+ + MGF + +Q +P +LA ++++ +++G+GKT AF++ Sbjct: 24 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 83 Query: 99 PAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEA 158 + + P+ + ++PT ELALQ V ++ +F+ + N+ + Sbjct: 84 AMLSQVEPANKYPQ----CLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG 139 Query: 159 EKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQIIKIL 217 +K+ + ++I TPG +LD K K +K ++DEAD ++ G +D+ +I ++L Sbjct: 140 QKISEQ--IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRML 197 Query: 218 PNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETD 257 P + Q +LFSAT V A+ + P P I + E + Sbjct: 198 PR-NCQMLLFSATFEDSVWKFAQK-VVPDPNVIKLKREEE 235 >3FMO-B nrPDB Length = 300 Score = 228 bits (581), Expect = 5e-60, Method: Composition-based stats. Identities = 62/218 (28%), Positives = 114/218 (52%), Gaps = 11/218 (5%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLI 98 V+ FEEL+L L+ + MGF + +Q +P +LA ++++ +++G+GKT AF++ Sbjct: 91 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 150 Query: 99 PAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEA 158 + + P+ + ++PT ELALQ V ++ +F+ + N+ + Sbjct: 151 AMLSQVEPANKYPQ----CLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG 206 Query: 159 EKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQIIKIL 217 +K+ + ++I TPG +LD K K +K ++DEAD ++ G +D+ +I ++L Sbjct: 207 QKISEQ--IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRML 264 Query: 218 PNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPE 255 P + Q +LFSAT V A+ + P P I + E Sbjct: 265 PR-NCQMLLFSATFEDSVWKFAQK-VVPDPNVIKLKRE 300 >1Q0U-A nrPDB Length = 219 Score = 212 bits (540), Expect = 3e-55, Method: Composition-based stats. Identities = 66/217 (30%), Positives = 116/217 (53%), Gaps = 11/217 (5%) Query: 42 EKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAI 101 +F ++AI+ + F T +Q R IP L G ++G ++TG+GKT A+L+P + Sbjct: 4 TQFTRFPFQPFIIEAIKTLRFYKPTEIQERIIPGALRGESMVGQSQTGTGKTHAYLLPIM 63 Query: 102 ELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIV----IGGANRRQE 157 E + R ++ PTRELA QI+ ++ +F + IV IGG ++++ Sbjct: 64 EKIKPE----RAEVQAVITAPTRELATQIYHETLKITKFCPKDRMIVARCLIGGTDKQKA 119 Query: 158 AEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKIL 217 EKL +++I TPGR+ D + + L++DEAD +L++GF ++ QI + Sbjct: 120 LEKLNVQPHIVIGTPGRINDFI-REQALDVHTAHILVVDEADLMLDMGFITDVDQIAARM 178 Query: 218 PNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVP 254 P +D Q ++FSAT K++ + + P F++V+ Sbjct: 179 P-KDLQMLVFSATIPEKLKPFLKKYM-ENPTFVHVLE 213 >2KBE-A nrPDB Length = 226 Score = 207 bits (528), Expect = 7e-54, Method: Composition-based stats. Identities = 59/205 (28%), Positives = 106/205 (51%), Gaps = 15/205 (7%) Query: 41 VEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAG--RDVLGAAKTGSGKTLAFLI 98 + F+EL L+ LK I M F + +Q R +P LL R+++ +++G+GKT AF + Sbjct: 21 AKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSL 80 Query: 99 PAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGA-NRRQE 157 + ++ P+ I + P+RELA Q V +E+ +F T +++ + + ++ Sbjct: 81 TMLTRVNPEDASPQ----AICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDSFEKNKQ 136 Query: 158 AEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILE-IGFEDEMRQIIKI 216 +++ TPG +LD L K + +K ++DEAD +L+ G D+ ++ + Sbjct: 137 I-----NAQVIVGTPGTVLD-LMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRF 190 Query: 217 LPNEDRQSMLFSATQTTKVEDLARI 241 LP +D Q +LFSAT V A+ Sbjct: 191 LP-KDTQLVLFSATFADAVRQYAKK 214 >4CDG-A nrPDB Length = 673 Score = 197 bits (500), Expect = 1e-50, Method: Composition-based stats. Identities = 79/429 (18%), Positives = 149/429 (34%), Gaps = 57/429 (13%) Query: 42 EKFEELKLS--QPTLKAIEK-MGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLI 98 E+F+ L + +K K G + Q I L G D TG GK+L + + Sbjct: 9 ERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQL 68 Query: 99 PAIELLHSLKFKPRNGTGIIVITPTREL-ALQIFGVARELMEFHSQTFGIVIGG------ 151 PA + +VI+P R L Q+ + + G Sbjct: 69 PACV----------SPGVTVVISPLRSLIVDQVQKLTS-----LDIPATYLTGDKTDSEA 113 Query: 152 ANRRQEAEKLMKGVNMLIATPG------RLLDHLQNTKGFVFKNLKALIIDEADRILEIG 205 N + K + +L TP RL+ L+N + K L +IDEA + + G Sbjct: 114 TNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLEN--LYERKLLARFVIDEAHCVSQWG 171 Query: 206 --FEDEMRQ---IIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNST 260 F + ++ + + P+ ++ +A + + L ++ + +F + + Sbjct: 172 HDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVF------SMSFN 225 Query: 261 ADGLEQGYVVCDSDKR--FLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLE 318 L+ YV+ K+ F L K + I++ S A+ L L L Sbjct: 226 RHNLK-YYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALA 284 Query: 319 LHGKQKQQKRTNTFFEF-CNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRV 377 H R ++ ++ T G+D P V ++I P Y Sbjct: 285 YHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQES 344 Query: 378 GRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPEN------KIANVQ--SQL 429 GR R + L+F T +++ L+ L + N + + + + ++ Sbjct: 345 GRAGRDGEIS-HCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITEC 403 Query: 430 EKLIKSNYY 438 ++ Y+ Sbjct: 404 RRIQLLAYF 412 >2OXC-A nrPDB Length = 230 Score = 195 bits (496), Expect = 3e-50, Method: Composition-based stats. Identities = 62/211 (29%), Positives = 107/211 (50%), Gaps = 10/211 (4%) Query: 44 FEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 FE L LS+P L+ + GF + VQ + IP G D++ AK+G+GKT F A++ Sbjct: 26 FESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDS 85 Query: 104 LHSLKFKPRNGTGIIVITPTRELALQIFGVARELM-EFHSQTFGIVIGGANRRQEAEKLM 162 L T I+++ PTRE+A+QI V + + + IGG Q+ +L Sbjct: 86 LVLENLS----TQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLK 141 Query: 163 KGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIG-FEDEMRQIIKILPNED 221 K ++ + +PGR+ ++ +++ I+DEAD++LE G F++++ I LP Sbjct: 142 K-CHIAVGSPGRIKQLIEL-DYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPA-S 198 Query: 222 RQSMLFSATQTTKVEDLARISLRPGPLFINV 252 +Q + SAT + + +R P F+ + Sbjct: 199 KQMLAVSATYPEFLANALTKYMR-DPTFVRL 228 >3DKP-A nrPDB Length = 245 Score = 195 bits (495), Expect = 5e-50, Method: Composition-based stats. Identities = 64/204 (31%), Positives = 105/204 (51%), Gaps = 8/204 (3%) Query: 45 EELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELL 104 +E K++ L+ I GF T +Q + IP +L GR++L +A TGSGKTLAF IP + L Sbjct: 32 QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL 91 Query: 105 HSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVI-GGANRRQEAEKLMK 163 G ++I+PTRELA QI ++ E ++ ++ K K Sbjct: 92 KQ---PANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSK 148 Query: 164 GVNMLIATPGRLLDHL-QNTKGFVFKNLKALIIDEADRILE---IGFEDEMRQIIKILPN 219 ++L+ TP RL+ L Q+ G +++ L++DE+D++ E GF D++ I + Sbjct: 149 KFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTS 208 Query: 220 EDRQSMLFSATQTTKVEDLARISL 243 + +FSAT VE +++L Sbjct: 209 HKVRRAMFSATFAYDVEQWCKLNL 232 >1GM5-A nrPDB Length = 780 Score = 184 bits (467), Expect = 8e-47, Method: Composition-based stats. Identities = 76/367 (20%), Positives = 147/367 (40%), Gaps = 56/367 (15%) Query: 80 RDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELME 139 + L GSGKT+ + ++ + G + PT LA+Q + E Sbjct: 390 MNRLLQGDVGSGKTVVAQLAILDNYEA-------GFQTAFMVPTSILAIQHYRRTVESFS 442 Query: 140 FHSQTFGIVIGGANRRQEAEKLMKG-----VNMLIATPGRLLDHLQNTKGFVFKNLKALI 194 + ++IG E EK+ G ++++I T + + + FKNL +I Sbjct: 443 KFNIHVALLIGATT-PSEKEKIKSGLRNGQIDVVIGTHALIQEDVH------FKNLGLVI 495 Query: 195 IDEADRILEIGFEDEMRQIIKILPNEDRQ--SMLFSATQTTKVEDLARISLRPGPLFINV 252 IDE R F + R+ L N+ + +++ SAT + LA G L + V Sbjct: 496 IDEQHR-----FGVKQRE---ALMNKGKMVDTLVMSATPIPRSMALAFY----GDLDVTV 543 Query: 253 VPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFL-------SSCNSVKYY 305 + E G ++ + R ++ F+++ + F+ S +VK Sbjct: 544 IDE----MPPGRKEVQTMLVPMDRVNEVYEFVRQEVMRGGQAFIVYPLIEESDKLNVKSA 599 Query: 306 AELLNYIDLPVLE------LHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVD 359 E+ Y+ V +HG+ Q+++ EF IL+ T V G+D+P + Sbjct: 600 VEMYEYLSKEVFPEFKLGLMHGRLSQEEKDRVMLEFAEGRYDILVSTTVIEVGIDVPRAN 659 Query: 360 WIIQFDPPDDPRDYIHRV-GRTARGTKGKGKSLMFLTPNELG--FLRYLKASKVPLNEYE 416 ++ +P +H++ GR RG + ++ FL ++G + L+ + + ++ Sbjct: 660 VMVIENPERFGLAQLHQLRGRVGRGGQ---EAYCFLVVGDVGEEAMERLRFFTLNTDGFK 716 Query: 417 FPENKIA 423 E + Sbjct: 717 IAEYDLK 723 >5V9X-A nrPDB Length = 877 Score = 177 bits (449), Expect = 9e-45, Method: Composition-based stats. Identities = 78/383 (20%), Positives = 133/383 (34%), Gaps = 65/383 (16%) Query: 58 EKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGI 117 F T QA + G + L A TGSGKTLA + AI+ L +P GT + Sbjct: 41 FTTAFAAPTPAQADAWSAISEGNNTLVIAPTGSGKTLAAFLWAIDRLADPAREPSQGTQV 100 Query: 118 IVITPTRELALQIFGVAR-------ELMEFH-----SQTFGIVIGGANRRQEAEKLMKGV 165 + ++P + LA+ + R + E H S T G+ G Q + Sbjct: 101 LYVSPLKALAVDVERNLRTPLTGITRVAERHGLPAPSITVGVRSGDTPPNQRRAMIANPP 160 Query: 166 NMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEI---GFEDEMRQIIKILPNEDR 222 ++LI TP L L + +++ +I+DE + + + L + Sbjct: 161 DVLITTPESLFLMLTSAARETLTSVRTVIVDEVHAVAATKRGAHLALSLERLDQLLDTPA 220 Query: 223 QSMLFSATQTTKVEDLARISLRPGPLFI---------NVVPETDNSTADGLEQGYVVCDS 273 Q + SAT E++AR P I ++ + L+ + D Sbjct: 221 QRIGLSATVRPP-EEVARFLSGQAPTTIVCPPAAKTFDLSVQVPVPDMANLDNNSIWPDV 279 Query: 274 DKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYI--------------------- 312 ++R + ++ + IVF +S + LN I Sbjct: 280 EER---IVDLVEAH--NSSIVFANSRRLAERLTSRLNEIHAERSGIELPAGPNPEVGGGA 334 Query: 313 --------------DLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAV 358 L HG +++R + + ++ T G+D+ AV Sbjct: 335 PAHLMGSGQANGAPPLLARAHHGSVSKEQRAQVEDDLKSGRLRAVVATSSLELGIDMGAV 394 Query: 359 DWIIQFDPPDDPRDYIHRVGRTA 381 D +IQ + P + RVGR Sbjct: 395 DLVIQVEAPPSVASGLQRVGRAG 417 >2WWY-A nrPDB Length = 591 Score = 177 bits (449), Expect = 9e-45, Method: Composition-based stats. Identities = 62/401 (15%), Positives = 141/401 (35%), Gaps = 31/401 (7%) Query: 51 QPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFK 110 + L+ + K+ +Q TI +AG++V TG GK+L + +PA+ Sbjct: 33 KDILQNVFKL--EKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALC-------- 82 Query: 111 PRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNM--L 168 +G +VI P L V ++L + + AE + K + + Sbjct: 83 -SDGF-TLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLI 140 Query: 169 IATPGRL----LDHLQNTKGFVFKNLKALIIDEADRILEIG--FEDEMRQI---IKILPN 219 TP ++ + + K + + + +DE + G F + + + + PN Sbjct: 141 YVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPN 200 Query: 220 EDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLL 279 + +AT V A+ L F + + Q +++ Sbjct: 201 ASLIGLTATAT--NHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQK--PSNTEDFIED 256 Query: 280 LFSFLK-RNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNA 338 + + R + + I++ S + L + + H + + +T ++ Sbjct: 257 IVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSAN 316 Query: 339 ERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNE 398 E +++ T G+D P V ++I +Y GR R K +++ + Sbjct: 317 EIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRD-DMKADCILYYGFGD 375 Query: 399 L-GFLRYLKASKVPLNEYEFPENKIANVQSQLEKLIKSNYY 438 + + V + + N+ S+ +++ + ++ Sbjct: 376 IFRISSMVVMENVGQQKLYEMVSYCQNI-SKCRRVLMAQHF 415 >5LBA-B nrPDB Length = 445 Score = 172 bits (437), Expect = 2e-43, Method: Composition-based stats. Identities = 63/379 (16%), Positives = 127/379 (33%), Gaps = 42/379 (11%) Query: 60 MGFTTM-TSVQARTIPPLLAG-RDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGI 117 GF + T +Q ++ G +DV TG+GK+L + +PA+ Sbjct: 16 FGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALL----------AKGIT 65 Query: 118 IVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMK---GVNMLIATPG- 173 IV++P L L + + + R++ L + +L TP Sbjct: 66 IVVSPLIALIQDQVDHLLTL-KVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPEM 124 Query: 174 --------RLLDHLQNTKGFVFKNLKALIIDEADRILEIG--FEDEMRQI---IKILPNE 220 L + L L++DEA + + G F + ++ L + Sbjct: 125 AASSSFQPTLNSLVSRHL------LSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHA 178 Query: 221 DRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLL 280 ++ +AT + + A + L+ P+ I P + ++ ++ D Sbjct: 179 PCVALTATATPQVQEDVFAALHLKK-PVAIFKTPCFRANLFYDVQFKELISDPYGNLKDF 237 Query: 281 F-SFLKRNQKKK----IIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEF 335 L + K IV+ + + + A L+ + H K +RT ++ Sbjct: 238 CLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDW 297 Query: 336 CNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLT 395 + +++ T G+D V ++ ++ Y GR R K L + Sbjct: 298 MEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSR 357 Query: 396 PNELGFLRYLKASKVPLNE 414 + ++ L E Sbjct: 358 NDRDQVSFLIRKEVAKLQE 376 >5LB8-A nrPDB Length = 518 Score = 172 bits (437), Expect = 2e-43, Method: Composition-based stats. Identities = 63/379 (16%), Positives = 127/379 (33%), Gaps = 42/379 (11%) Query: 60 MGFTTM-TSVQARTIPPLLAG-RDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGI 117 GF + T +Q ++ G +DV TG+GK+L + +PA+ Sbjct: 16 FGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALL----------AKGIT 65 Query: 118 IVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMK---GVNMLIATPG- 173 IV++P L L + + + R++ L + +L TP Sbjct: 66 IVVSPLIALIQDQVDHLLTL-KVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPEM 124 Query: 174 --------RLLDHLQNTKGFVFKNLKALIIDEADRILEIG--FEDEMRQI---IKILPNE 220 L + L L++DEA + + G F + ++ L + Sbjct: 125 AASSSFQPTLNSLVSRHL------LSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHA 178 Query: 221 DRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLL 280 ++ +AT + + A + L+ P+ I P + ++ ++ D Sbjct: 179 PCVALTATATPQVQEDVFAALHLKK-PVAIFKTPCFRANLFYDVQFKELISDPYGNLKDF 237 Query: 281 F-SFLKRNQKKK----IIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEF 335 L + K IV+ + + + A L+ + H K +RT ++ Sbjct: 238 CLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDW 297 Query: 336 CNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLT 395 + +++ T G+D V ++ ++ Y GR R K L + Sbjct: 298 MEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSR 357 Query: 396 PNELGFLRYLKASKVPLNE 414 + ++ L E Sbjct: 358 NDRDQVSFLIRKEVAKLQE 376 >2VA8-A nrPDB Length = 715 Score = 116 bits (291), Expect = 2e-26, Method: Composition-based stats. Identities = 81/443 (18%), Positives = 159/443 (35%), Gaps = 78/443 (17%) Query: 45 EELKLSQPTLKAIEKMGFTTMTSVQARTIPP-LLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 E+LKL ++ I+K G + Q + LL G +L + TGSGKTL + I Sbjct: 11 EDLKLPSNVIEIIKKRGIKKLNPPQTEAVKKGLLEGNRLLLTSPTGSGKTLIAEMGIISF 70 Query: 104 LHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMK 163 L +NG I +TP R L + + ++ E + G + + +K Sbjct: 71 L------LKNGGKAIYVTPLRALTNEKYLTFKDW-ELIGFKVAMTSGDYDTD---DAWLK 120 Query: 164 GVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQ 223 +++I T +L D L + + ++DE + + + + + + R Sbjct: 121 NYDIIITTYEKL-DSLWRHRPEWLNEVNYFVLDELHYLNDPERGPVVESV--TIRAKRRN 177 Query: 224 SMLFSATQTTKVEDLARISLRPGPLFINVVPET---DNSTADGLEQGYVVCDSDKRFLLL 280 + SAT + + +A+ L P+ N P + ++ Y V D + Sbjct: 178 LLALSATISN-YKQIAK-WLGAEPVATNWRPVPLIEGVIYPERKKKEYNVIFKDNTTKKV 235 Query: 281 --------FSFLKRNQKKKIIVFLSSCNSVKYYA------------------ELLNYID- 313 ++ ++ +++VF +S + A E+L +D Sbjct: 236 HGDDAIIAYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDENALSEILKQLDD 295 Query: 314 -----------------LPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIP 356 V H + R F + +++ T A G+++P Sbjct: 296 IEEGGSDEKELLKSLISKGVAYHHAGLSKALRDLIEEGFRQRKIKVIVATPTLAAGVNLP 355 Query: 357 AVDWII--QFDPPDDPRDYIHRV---------GRTARGTKGK-GKSLMFLTPNELGFLRY 404 A II + Y + GR R + G+S++ + ++ R Sbjct: 356 ARTVIIGDIYRFNKKIAGYYDEIPIMEYKQMSGRAGRPGFDQIGESIV-VVRDKEDVDRV 414 Query: 405 LKASKVPLNEYEFPENKIANVQS 427 K K L++ E E+K+ + ++ Sbjct: 415 FK--KYVLSDVEPIESKLGSERA 435 >1WP9-A nrPDB Length = 494 Score = 113 bits (283), Expect = 2e-25, Method: Composition-based stats. Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 8/127 (6%) Query: 274 DKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHG--------KQKQ 325 DK ++ L+R Q KIIVF + + K L + G Q Sbjct: 346 DKLKEIIREQLQRKQNSKIIVFTNYRETAKKIVNELVKDGIKAKRFVGQASKENDRGLSQ 405 Query: 326 QKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTK 385 +++ EF E +L+ T V GLD+P VD ++ ++P I R GRT R Sbjct: 406 REQKLILDEFARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSIQRRGRTGRHMP 465 Query: 386 GKGKSLM 392 G+ LM Sbjct: 466 GRVIILM 472 Score = 65.8 bits (159), Expect = 4e-11, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 55/133 (41%), Gaps = 8/133 (6%) Query: 68 VQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELA 127 + I + L TG GKTL I ++ + + G ++++ PT+ L Sbjct: 12 IYQEVIYAKCKETNCLIVLPTGLGKTL------IAMMIAEYRLTKYGGKVLMLAPTKPLV 65 Query: 128 LQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVF 187 LQ R L + + G + + ++ + +++ATP + + L + Sbjct: 66 LQHAESFRRLFNLPPEKIVALTGEKSPEERSKAWAR-AKVIVATPQTIENDLLAGR-ISL 123 Query: 188 KNLKALIIDEADR 200 +++ ++ DEA R Sbjct: 124 EDVSLIVFDEAHR 136 >2P6R-A nrPDB Length = 702 Score = 112 bits (279), Expect = 6e-25, Method: Composition-based stats. Identities = 65/395 (16%), Positives = 134/395 (33%), Gaps = 60/395 (15%) Query: 57 IEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTG 116 +++ G + QA + + +G+++L A T +GKTL + + + G Sbjct: 18 LKEEGIEELFPPQAEAVEKVFSGKNLLLAMPTAAGKTLLAEMAMV-------REAIKGGK 70 Query: 117 IIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLL 176 + + P R LA + + ++ + GI G R E ++++ T + Sbjct: 71 SLYVVPLRALAGEKYESFKKWEKI-GLRIGISTGDYESRDEHLG---DCDIIVTTSEKA- 125 Query: 177 DHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKI---LPNEDRQSMLFSATQTT 233 D L + K + L++DE +L+ +I+ N+ + + SAT Sbjct: 126 DSLIRNRASWIKAVSCLVVDEIH-LLDSEKRGATLEILVTKMRRMNKALRVIGLSATAPN 184 Query: 234 KVEDLARISLRPGPL-FINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKR--NQKK 290 V ++A + VP + +G + + S R + ++ + Sbjct: 185 -VTEIAEWLDADYYVSDWRPVPLVEGVLCEGTLELFDGAFSTSRRVKFEELVEECVAENG 243 Query: 291 KIIVFLSSCNSVKYYAELL--------NYIDLPVLEL----------------------H 320 ++VF S+ + A L L L H Sbjct: 244 GVLVFESTRRGAEKTAVKLSAITAKYVENEGLEKAILEENEGEMSRKLAECVRKGAAFHH 303 Query: 321 GKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQ-------FDPPDDPRDY 373 +R F +++ T A G+++PA I++ + +Y Sbjct: 304 AGLLNGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPARRVIVRSLYRFDGYSKRIKVSEY 363 Query: 374 IHRVGRTARGT---KGKGKSLMFLTPNELGFLRYL 405 GR R +G+ ++ E+ RY+ Sbjct: 364 KQMAGRAGRPGMDERGEAIIIVGKRDREIAVKRYI 398 >2FWR-A nrPDB Length = 472 Score = 110 bits (276), Expect = 1e-24, Method: Composition-based stats. Identities = 26/125 (20%), Positives = 56/125 (44%), Gaps = 5/125 (4%) Query: 269 VVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKR 328 + +S + L L+R++K KII+F + + +P + + +++R Sbjct: 329 IAFNSKNKIRKLREILERHRKDKIIIFT---RHNELVYRISKVFLIPAIT--HRTSREER 383 Query: 329 TNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKG 388 F ++ + V G+D+P + + R+YI R+GR R +KGK Sbjct: 384 EEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREYIQRLGRILRPSKGKK 443 Query: 389 KSLMF 393 +++++ Sbjct: 444 EAVLY 448 >2ZJ8-A nrPDB Length = 720 Score = 108 bits (269), Expect = 7e-24, Method: Composition-based stats. Identities = 78/472 (16%), Positives = 163/472 (34%), Gaps = 70/472 (14%) Query: 45 EELKLSQPTLKAIEKMGFTTMTSVQARTIPP-LLAGRDVLGAAKTGSGKTLAFLIPAIEL 103 +EL++ + +++ G + QA + +L G++ L + T SGKTL I + Sbjct: 4 DELRVDERIKSTLKERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAMVHR 63 Query: 104 LHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMK 163 + + G + I P + LA + F ++ + + G + + E Sbjct: 64 ILT------QGGKAVYIVPLKALAEEKFQEFQDWEKI-GLRVAMATGDYDSKDEWLG--- 113 Query: 164 GVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQ 223 +++IAT + D L K++K L+ DE I + I+ + + Q Sbjct: 114 KYDIIIATAEK-FDSLLRHGSSWIKDVKILVADEIHLIGSRDRGATLEVILAHMLGKA-Q 171 Query: 224 SMLFSATQ--TTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSD--KRFLL 279 + SAT ++ + I QG+V + RF Sbjct: 172 IIGLSATIGNPEELAEWL------NAELIVSDWRPVKLRRGVFYQGFVTWEDGSIDRFSS 225 Query: 280 LFSFLKR--NQKKKIIVFLSSCNSVKYYAELLNYIDLP---------------------- 315 + +KK ++F++ + A L+ Sbjct: 226 WEELVYDAIRKKKGALIFVNMRRKAERVALELSKKVKSLLTKPEIRALNELADSLEENPT 285 Query: 316 -----------VLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWII-- 362 V H + +R F ++ T + G++ PA II Sbjct: 286 NEKLAKAIRGGVAFHHAGLGRDERVLVEENFRKGIIKAVVATPTLSAGINTPAFRVIIRD 345 Query: 363 -----QFDPPDDPRDYIHR-VGRTARGTKGK-GKSLMFLTPNELGFLRYLKASKVPLNEY 415 F P +H+ +GR R + G+ ++ T ++ + P + Sbjct: 346 IWRYSDFGMERIPIIEVHQMLGRAGRPKYDEVGEGIIVSTSDDPREVMNHYIFGKPEKLF 405 Query: 416 EFPENKIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDK 467 N+ +N++SQ+ LI + + + T ++ + + ++ K Y +++ Sbjct: 406 SQLSNE-SNLRSQVLALIAT--FGYSTVEEILKFISNTFYAYQRKDTYSLEE 454 >5AGA-A nrPDB Length = 830 Score = 94.3 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 64/437 (14%), Positives = 129/437 (29%), Gaps = 97/437 (22%) Query: 48 KLSQPTLKAIEKMGFTTMTSVQARTIPP--LLAGRDVLGAAKTGSGKTLAFLIPAIELLH 105 L + L+ G M QA + +L G++++ +A T +GKTL + ++ + Sbjct: 11 GLPKAVLEKYHSFGVKKMFEWQAECLLLGQVLEGKNLVYSAPTSAGKTLVAELLILKRVL 70 Query: 106 SLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGV 165 ++ K + I P +A + + L + +G + + L Sbjct: 71 EMRKK------ALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSL---- 120 Query: 166 NMLIATPGRLLDHLQNTKGFV-FKNLKALIIDEADRILEIGFEDEMRQIIKI----LPNE 220 ++ + T R + L +++DE +L + +++ + + Sbjct: 121 DIAVCTIERANGLINRLIEENKMDLLGMVVVDELH-MLGDSHRGYLLELLLTKICYITRK 179 Query: 221 D--------------RQSMLFSATQTT----KVEDLARIS---LRPGPLF--INVVPETD 257 Q + SAT A + RP PL + V Sbjct: 180 SASCQADLASSLSNAVQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIY 239 Query: 258 NSTADGLEQGYVVCDSDKRFLLLFSFLKRN--QKKKIIVFLSSCNSVKYYAELLNYIDLP 315 +S+ + + + + S +++F S + A+++ Sbjct: 240 DSSMKLVREFEPMLQVKGDEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYN 299 Query: 316 -------------------------------------------------VLELHGKQKQQ 326 V H + Sbjct: 300 LHHQAEGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFE 359 Query: 327 KRTNTFFEFCNAERGILICTDVAARGLDIPAVDWII---QFDP-PDDPRDYIHRVGRTAR 382 +R F +L T + G+++PA II F P D Y VGR R Sbjct: 360 ERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGR 419 Query: 383 GT-KGKGKSLMFLTPNE 398 G+S++ +E Sbjct: 420 KGVDTVGESILICKNSE 436 >5TNU-A nrPDB Length = 459 Score = 85.8 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 49/129 (37%), Gaps = 5/129 (3%) Query: 269 VVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKR 328 + +S + L L+ + +KIIVF + +PV+ + +R Sbjct: 324 IAVNSQSKIEKLREILQEYKNEKIIVFTRDTQMA---YRISKTFLIPVVTYKTDK--DER 378 Query: 329 TNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKG 388 +F + E +++ + V G+D+P I R ++ R+GR R + Sbjct: 379 EEILQKFRDGEYRVIVASTVFDEGVDVPDATLAIVMGGYGTKRQFLQRLGRILRKKDKEA 438 Query: 389 KSLMFLTPN 397 + +T Sbjct: 439 LLIEIVTKG 447 >1D9Z-A nrPDB Length = 657 Score = 81.6 bits (200), Expect = 7e-16, Method: Composition-based stats. Identities = 52/304 (17%), Positives = 101/304 (33%), Gaps = 51/304 (16%) Query: 171 TPGRLLDHLQNTKGFVFKNLKALIIDEADRIL------------------EIGFE----- 207 TP LLD+ + +I+DE+ L + GF Sbjct: 320 TPYTLLDYFPDDF--------LIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSAL 371 Query: 208 DEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQG 267 D + + Q + SAT L P + + ++ Sbjct: 372 DNRPLTFEEFEQKINQIIYVSATPGP-------YELEHSPGVVEQIIRPTGLLDPTIDVR 424 Query: 268 YVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQK 327 D + ++RN+ + +V + + + L + V LH + K + Sbjct: 425 PTKGQIDDLIGEIRERVERNE--RTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLE 482 Query: 328 RTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDP-----RDYIHRVGRTAR 382 R + + +L+ ++ GLDIP V + D + R I +GR AR Sbjct: 483 RIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAAR 542 Query: 383 GTKGKGKSLMF---LTPNELGFLRYLKASKVPLNEYEFPENKI-ANVQSQLEKLIKSNYY 438 G +M+ +T + ++ K + EY + V+ ++ +I++ Y Sbjct: 543 NAN--GHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEIRDVIRATYA 600 Query: 439 LHQT 442 +T Sbjct: 601 AEET 604 Score = 28.4 bits (62), Expect = 8.0, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 26/62 (41%), Gaps = 10/62 (16%) Query: 88 TGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGI 147 TG+GKT I + + KP +VI + LA Q++ +E ++ + + Sbjct: 41 TGTGKTFT-----ISNVIAQVNKP-----TLVIAHNKTLAGQLYSELKEFFPHNAVEYFV 90 Query: 148 VI 149 Sbjct: 91 SY 92 >2NMV-A nrPDB Length = 661 Score = 77.0 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 40/244 (16%), Positives = 84/244 (34%), Gaps = 39/244 (15%) Query: 171 TPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSM----- 225 TP LLD+ + +++DE+ + ++R + +Q + Sbjct: 321 TPYTLLDYFPDDF--------MIVVDESHVTI-----PQVRGMFNGD-QARKQVLVDHGF 366 Query: 226 -LFSA--TQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFL---- 278 L SA + + E+ + + P T + +EQ + Sbjct: 367 RLPSALDNRPLRFEEFEKHMHNIVYVSATPGPYEIEHTDEMVEQIIRPTGLLDPLIDVRP 426 Query: 279 ---LLFSFLKR-----NQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTN 330 + + + ++++V + + + L I + V LH + K +R Sbjct: 427 IEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIKTLERIE 486 Query: 331 TFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDP-----RDYIHRVGRTARGTK 385 + + +L+ ++ GLDIP V + D + R I +GR AR + Sbjct: 487 IIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAE 546 Query: 386 GKGK 389 G+ Sbjct: 547 GRVI 550 >5JCF-A nrPDB Length = 701 Score = 73.9 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 35/243 (14%), Positives = 73/243 (30%), Gaps = 23/243 (9%) Query: 228 SATQTTKVEDLARISLRPGPLFINVVPETDNSTAD-GLEQGYVVCDSDKRFLLLFSFLKR 286 +A E L + + + + Y K L + Sbjct: 337 TAESDDDEEPLVSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTK 396 Query: 287 NQKKKIIVFLSSCNSVKYYAELL------NYIDLPVLELHGK--------QKQQKRTNTF 332 ++ + I+F + S + + + L G Q ++ Sbjct: 397 TEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVI 456 Query: 333 FEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLM 392 +F +LI T VA GLDI + +I++ + + GR R + + Sbjct: 457 DKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA-RADESTYALVA 515 Query: 393 F-----LTPNELGFLRYLKASKVPLNEYEF-PENKIANVQS-QLEKLIKSNYYLHQTAKD 445 + ++ R K E PE + +Q QL+ +++ + + Sbjct: 516 SSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRK 575 Query: 446 GYR 448 Y+ Sbjct: 576 TYK 578 Score = 53.8 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 56/146 (38%), Gaps = 7/146 (4%) Query: 59 KMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGII 118 MG T+ Q P L G +++ TGSGKT + + L + G +I Sbjct: 2 AMGDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQG-KVI 60 Query: 119 VITPTRELALQIF-GVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATP----G 173 V+ L Q ++ Q G+ G + + +++K +++I T Sbjct: 61 VLVNKVPLVEQHLRKEFNPFLKHWYQVIGL-SGDSELKISFPEVVKRYDVIICTAQILEN 119 Query: 174 RLLDHLQNTKGFVFKNLKALIIDEAD 199 LL+ + + + +IID+ Sbjct: 120 SLLNATEEDESVRLSDFSLIIIDQCH 145 >6G19-A nrPDB Length = 696 Score = 73.9 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 32/176 (18%), Positives = 62/176 (35%), Gaps = 24/176 (13%) Query: 276 RFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELL----------NYIDLPVLELHGK--- 322 R +L F + + + I+F + S ++ + + H Sbjct: 381 RNTILEQFTRSEESSRGIIFTKTRQSTYALSQWIMENAKFAEVGVKAHHLIGAGHSSEVK 440 Query: 323 -QKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTA 381 Q ++ +F E +LI T VA GLDI + +I++ + + GR Sbjct: 441 PMTQTEQKEVISKFRTGEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA- 499 Query: 382 RG---------TKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPENKIANVQSQ 428 R + G G + + + + Y ++V + E +KI +Q Q Sbjct: 500 RADESTYVLVTSSGSGVTEREIVNDFREKMMYKAINRVQNMKPEEYAHKILELQVQ 555 Score = 57.7 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 10/143 (6%) Query: 64 TMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPT 123 + Q P L G++++ TGSGKT + + L K +G +IV+ Sbjct: 2 QLRPYQMEVAQPALDGKNIIICLPTGSGKTRVAVYITKDHLDKKKQASESG-KVIVLVNK 60 Query: 124 RELALQIFGVARELMEFHSQTFGIV--IGGANRRQEAEKLMKGVNMLIATPGRLLDHLQN 181 LA Q+F +E + + + I+ G + +++K +++I+T L + L N Sbjct: 61 VMLAEQLFR--KEFNPYLKKWYRIIGLSGDTQLKISFPEVVKSYDVIISTAQILENSLLN 118 Query: 182 T-----KGFVFKNLKALIIDEAD 199 G + +IIDE Sbjct: 119 LESGDDDGVQLSDFSLIIIDECH 141 >5JBJ-A nrPDB Length = 680 Score = 72.7 bits (177), Expect = 4e-13, Method: Composition-based stats. Identities = 32/167 (19%), Positives = 55/167 (32%), Gaps = 26/167 (15%) Query: 236 EDLARISLRPGPL--FINVVPETDNSTADGL--EQGYVVCDSDKRFLLLFSFLKRNQKK- 290 + A P F+ E + +T L +Q Y + R L L+ + + Sbjct: 314 QFYADKRDTKDPTERFLATTFEENRATLQALAGDQRY----ENPRLSKLEEILQEHFQPP 369 Query: 291 ---KIIVFLSSCNSVKYYAELLNY------IDLPVLELHG--------KQKQQKRTNTFF 333 + IVF + S L + L G Q ++ + Sbjct: 370 GSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVIT 429 Query: 334 EFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRT 380 F E +L T VA GLDIP + ++++ + + GR Sbjct: 430 LFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRA 476 Score = 58.9 bits (141), Expect = 6e-09, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 52/134 (38%), Gaps = 9/134 (6%) Query: 69 QARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELAL 128 Q + P L GR+ + TG+GKT A + + + R G + V+ L Sbjct: 13 QLEAVAPALRGRNSIVWLPTGAGKTRAAV-----HVCRRHLEGRRGGRVAVLVNKVHLVQ 67 Query: 129 QIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHL---QNTKGF 185 Q ++ + V G ++ + +L KG +++I T L + L + Sbjct: 68 QHLEKEFHVLR-DAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARV 126 Query: 186 VFKNLKALIIDEAD 199 + L+IDE Sbjct: 127 ELTDFSLLVIDECH 140 >4GL2-A nrPDB Length = 699 Score = 72.3 bits (176), Expect = 4e-13, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 44/119 (36%), Gaps = 14/119 (11%) Query: 276 RFLLLFSFLKRNQKKKIIVFLSSCNSV----------KYYAELLNYIDLPVLELHGK--- 322 R ++ + + + + I+F + S + +AE+ + H Sbjct: 387 RNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFK 446 Query: 323 -QKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRT 380 Q ++ +F + +LI T VA GLDI + +I++ + + GR Sbjct: 447 PMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA 505 Score = 60.8 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 32/142 (22%), Positives = 59/142 (41%), Gaps = 8/142 (5%) Query: 64 TMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPT 123 + Q P L G++++ TG GKT + A + L K G +IV+ Sbjct: 7 QLRPYQMEVAQPALEGKNIIICLPTGCGKTRVAVYIAKDHLDKKKKASEPG-KVIVLVNK 65 Query: 124 RELALQIF-GVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRL---LDHL 179 L Q+F + ++ + G+ G + +++K +++I+T L L +L Sbjct: 66 VLLVEQLFRKEFQPFLKKWYRVIGL-SGDTQLKISFPEVVKSCDIIISTAQILENSLLNL 124 Query: 180 QNT--KGFVFKNLKALIIDEAD 199 +N G + +IIDE Sbjct: 125 ENGEDAGVQLSDFSLIIIDECH 146 >3P4X-A nrPDB Length = 413 Score = 71.6 bits (174), Expect = 8e-13, Method: Composition-based stats. Identities = 66/351 (18%), Positives = 120/351 (34%), Gaps = 59/351 (16%) Query: 76 LLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVAR 135 ++ G+ A TG GKT F + + + R G ++ PT L Q + Sbjct: 32 IVQGKSFTMVAPTGVGKT-TFGM------MTALWLARKGKKSALVFPTVTLVKQTLERLQ 84 Query: 136 ELMEFHSQTFGIVIGGANRRQEAEKLMKGV---NMLI-----ATPGRLLDHLQNTKGFVF 187 +L + + FG +E + ++L+ + R + L + Sbjct: 85 KLADEKVKIFGFYSSMKKEEKEKFEKSFEEDDYHILVFSTQFVSKNR--EKLSQKRFDFV 142 Query: 188 KNLKALIIDEA----DRILEI-GFEDEMRQ----------IIKILPNEDRQSMLF-SAT- 230 + +A D +L + G +E+ + I + N ++ SAT Sbjct: 143 FVDDVDAVLKASRNIDTLLMMVGIPEEIIRKAFSTIKQGKIYERPKNLKPGILVVSSATA 202 Query: 231 QTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKK 290 + + L L +N S A + + S ++ + L + Sbjct: 203 KPRGIRPLLFRDL------LNFTVGRLVSVARNITHVRISSRSKEKLVELLEIFR----D 252 Query: 291 KIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDV-- 348 I++F + K E L V E + F +F + ILI Sbjct: 253 GILIFAQTEEEGKELYEYLKRFKFNVGE-----TWSEFEKNFEDFKVGKINILIGVQAYY 307 Query: 349 --AARGLDIP-AVDWIIQFDPPDDPR--DYIHRVGRTAR---GTKGKGKSL 391 RG+D+P + ++I + P P YI GR++R G KG S+ Sbjct: 308 GKLTRGVDLPERIKYVIFWGTPSGPDVYTYIQASGRSSRILNGVLVKGVSV 358 >5N8S-A nrPDB Length = 944 Score = 71.2 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 87/467 (18%), Positives = 145/467 (31%), Gaps = 118/467 (25%) Query: 71 RTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQI 130 I + + +L TG GKT +P I L ++ + II P R A+ I Sbjct: 161 DIIQAVRENQVILIVGSTGCGKTT--QVPQILLDDAISRGCASSCRIICTQPRRISAIAI 218 Query: 131 FG-VARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKN 189 V+ E E + G R E+ K + ++ T G LL LQ+ N Sbjct: 219 AEWVSYERCESLGNSV-----GYQIRLESRKARERASITYCTTGVLLQQLQSDPLM--HN 271 Query: 190 LKALIIDEADRI-----LEIGFEDEMRQIIKILPNEDRQSMLFSATQTT----------- 233 L LI+DE L +G ++ I+ P D + +L SAT Sbjct: 272 LSVLILDEIHERSVETDLLMGL---LKVILPHRP--DLKVILMSATVREQDFCDYFNNCP 326 Query: 234 -------------------------KVEDLARISLRPGPLFINVVPETDNST-ADGLEQG 267 + + + P + E + Sbjct: 327 MFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNS 386 Query: 268 Y-------------VVCDSDKRFLLLFSFLKRNQKKKII-VFLSSCNSVKYYAELLNY-- 311 Y C+ L ++ N+ + I VFL + + +L+ Sbjct: 387 YDSRVLDKLRLPESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPK 446 Query: 312 --------IDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWII- 362 + V LH + ++ F +R ++I T +A + I V ++I Sbjct: 447 TSKGQRWRDHMAVFPLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVIN 506 Query: 363 -------QFDPPDDPRDY----------IHRVGRTARGTKGKGKSLMFLTPNELGFLRYL 405 +D + + R GR R G + R Sbjct: 507 SGRTKATNYDIETNIQSLDEVWVTKANTQQRRGRAGR--VRPGICYNLFSRA-----RED 559 Query: 406 KASKVPLNEYEFPENKIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQ 452 + +P E ++S+LE +I S LH D YR +LQ Sbjct: 560 RMDDIPTPEI---------LRSKLESIILSLKLLH--IDDPYR-FLQ 594 >6C90-A nrPDB Length = 734 Score = 70.8 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 96/538 (17%), Positives = 163/538 (30%), Gaps = 131/538 (24%) Query: 47 LKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHS 106 L L KA ++ F + + Q I + + VL +A T +GKT+ L Sbjct: 56 LPLKPRVGKAAKEYPF-ILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALAL-- 112 Query: 107 LKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVN 166 R +I +P + L+ Q + RE+ E Q G++ G A L+ Sbjct: 113 -----REKQRVIFTSPIKALSNQKY---REMYEEF-QDVGLMTGDVTINPTASCLVMTTE 163 Query: 167 MLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSML 226 + L + V + + +I DE + + + I +LP+ L Sbjct: 164 I--------LRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFL 215 Query: 227 FSATQTTK---VEDLARIS----------LRPGPLFIN-----------VVPETDNSTAD 262 SAT E + + RP PL VV E + D Sbjct: 216 -SATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFRED 274 Query: 263 GLEQGYVVCDS-------DKR-----------FLLLFSFLKRNQKKKIIVFLSSCNSVKY 304 V D++ + + + +I+F S + Sbjct: 275 NFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEA 334 Query: 305 YAELLNYIDLPVLE---------------------------------------LHGKQKQ 325 YA + +D E HG Sbjct: 335 YALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLP 394 Query: 326 QKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPD---------DPRDYIHR 376 + F L T+ A G+++P ++ + +YI Sbjct: 395 ILKETIEILFSEGLIKALFATETFAMGINMP-ARTVLFTNARKFDGKDFRWISSGEYIQM 453 Query: 377 VGRTARGTK-GKGKSLMFLTPNELGFL--RYLKASKVPLNE-----YEFPENKIANVQSQ 428 GR R +G ++ + + + LK S PLN Y N + + Sbjct: 454 SGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEIN 513 Query: 429 LEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAK-VAKSYGFPVPPKV 485 E +++ ++Y Q YR A +TV Q+D+L K V + GF V Sbjct: 514 PEYMLEKSFYQFQH----YR------AIPGSRTVLQMDELKCRKRVLRRLGFATSSDV 561 >1C4O-A nrPDB Length = 664 Score = 70.8 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 34/204 (16%), Positives = 68/204 (33%), Gaps = 14/204 (6%) Query: 231 QTTKVEDLARISLRPGPLFINVVPETDNSTADG---LEQGYVVCDSDKRFLLLFSFLKRN 287 +V + +S PGP + L+ V ++ + L L ++ Sbjct: 376 FLERVSQVVFVSATPGPFELAHSGRVVEQIIRPTGLLDPLVRVKPTENQILDLMEGIRER 435 Query: 288 --QKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILIC 345 + ++ +V + + + L + LH + KR + L+ Sbjct: 436 AARGERTLVTVLTVRMAEELTSFLVEHGIRARYLHHELDAFKRQALIRDLRLGHYDCLVG 495 Query: 346 TDVAARGLDIPAVDWIIQFDPPDDP-----RDYIHRVGRTARGTKGKGKSLMFLTPNELG 400 ++ GLDIP V + D + R I +GR AR + G+ ++ Sbjct: 496 INLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAR--GEVWLYADRVSEA 553 Query: 401 FLRYLKASKVPLNEYEF--PENKI 422 R ++ + E E+ I Sbjct: 554 MQRAIEETNRRRALQEAYNLEHGI 577 Score = 35.0 bits (79), Expect = 0.073, Method: Composition-based stats. Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 21/88 (23%) Query: 59 KMGFTTMTSV--QARTIPPLLAG-RD------VLGAAKTGSGKTLAFLIPAIELLHSLKF 109 + + Q + I L+ RD +LGA TG+GKT + +++ +L Sbjct: 1 TFRYRGPSPKGDQPKAIAGLVEALRDGERFVTLLGA--TGTGKT----VTMAKVIEAL-- 52 Query: 110 KPRNGTGIIVITPTRELALQIFGVAREL 137 G +V+ P + LA Q+ REL Sbjct: 53 ----GRPALVLAPNKILAAQLAAEFREL 76 >5VHD-D nrPDB Length = 870 Score = 68.1 bits (165), Expect = 8e-12, Method: Composition-based stats. Identities = 72/432 (16%), Positives = 138/432 (31%), Gaps = 100/432 (23%) Query: 42 EKFEELKLSQPTLKAIEKMGFTT--MTSVQARTIPPLLAGRDVLGAA-KTGSGKTLAFLI 98 + E+L+ + L+ IE F + + + ++ V + +TG GKT + Sbjct: 36 QLLEDLQKKKTDLRYIEMQRFREKLPSYGMQKELVNMIDNHQVTVISGETGCGKTT--QV 93 Query: 99 PAIELLHSLKFKPRNGTGIIVITPTRELALQIFG-VARELMEFHSQTFGIVIGGANRRQE 157 L + ++ + I+ P R A+ + VA E E G R + Sbjct: 94 TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGNGNST---GYQIRLQ 150 Query: 158 AEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEAD-RILEIG-FEDEMRQIIK 215 + K ++L T G +L LQ+ ++ +++DE R L+ ++ ++ Sbjct: 151 SRLPRKQGSILYCTTGIILQWLQSDP--HLSSVSHIVLDEIHERNLQSDVLMTVVKDLLS 208 Query: 216 ILPNEDRQSMLFSATQ--------------------------------TTKVE------- 236 P D + +L SAT K+ Sbjct: 209 YRP--DLKVVLMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEKIRYVPEQKE 266 Query: 237 ---DLARISLR------PGPLFINVVPETDNSTADGLEQGY-------VVCDSDKRFLL- 279 + ++ + + E L Q Y V D++ L Sbjct: 267 HRSQFKKGFMQGHVNRQEKYYYEAIYKERWPGYLRELRQRYSASTVDVVEMMDDEKVDLN 326 Query: 280 -----LFSFLKRNQKKKIIVFLSSCNSVKYYAELL------NYIDLPVLELHGKQKQQKR 328 + + + I+VFL +++ +LL ++ LH + Sbjct: 327 LIAALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFIIIPLHSLMPTVNQ 386 Query: 329 TNTFFEFCNAERGILICTDVAARGLDIPAVDWII--------QFDPPDDP---------- 370 T F R I+I T++A + I V ++I FD ++ Sbjct: 387 TQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSK 446 Query: 371 RDYIHRVGRTAR 382 + R GR R Sbjct: 447 ANAKQRKGRAGR 458 >3TBK-A nrPDB Length = 555 Score = 67.7 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 35/212 (16%), Positives = 65/212 (30%), Gaps = 31/212 (14%) Query: 229 ATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQ 288 A +L R V + N L Y+V + Sbjct: 339 AAFDETERELTRRFEEKLEELEKVSRDPSNENPK-LRDLYLVLQEEYHLK---------P 388 Query: 289 KKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTN------------TFFEFC 336 + K I+F+ + V + + G + RTN F Sbjct: 389 ETKTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGRTNRATGMTLPAQKCVLEAFR 448 Query: 337 -NAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLT 395 + + ILI T VA G+DI + +I ++ + I GR R K + + Sbjct: 449 ASGDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGR-GRARDSK--CFLLTS 505 Query: 396 PNELGFLRYLKASKVPLNEYEFPENKIANVQS 427 ++ ++ K + + + I +Q+ Sbjct: 506 SADV-----IEKEKANMIKEKIMNESILRLQT 532 Score = 58.1 bits (139), Expect = 8e-09, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 48/140 (34%), Gaps = 8/140 (5%) Query: 64 TMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVIT-- 121 + Q P G++ + A TG GKT L+ E + G ++ Sbjct: 4 KPRNYQLELALPAKKGKNTIICAPTGCGKTFVSLL-ICEHHLKKFPCGQKG-KVVFFANQ 61 Query: 122 -PTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 P E Q V E + G + + +++ +++I TP L+++L Sbjct: 62 IPVYE---QQATVFSRYFERLGYNIASISGATSDSVSVQHIIEDNDIIILTPQILVNNLN 118 Query: 181 NTKGFVFKNLKALIIDEADR 200 N +I DE Sbjct: 119 NGAIPSLSVFTLMIFDECHN 138 >2OCA-A nrPDB Length = 510 Score = 67.3 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 56/399 (14%), Positives = 131/399 (32%), Gaps = 47/399 (11%) Query: 69 QARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELAL 128 Q + L R + T +G++L I+ L + + I++I PT L Sbjct: 118 QKDAVFEGLVNRRRILNLPTSAGRSL------IQALLARYYLENYEGKILIIVPTTALTT 171 Query: 129 QIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFK 188 Q+ + F + GGA++ +K +++ T ++ F Sbjct: 172 QMADDFVDYRLFSHAMIKKIGGGASKD---DKYKNDAPVVVGTWQTVV----KQPKEWFS 224 Query: 189 NLKALIIDEAD----------------RILEIGFEDEMRQIIKILPNEDRQSMLFS---- 228 ++ DE + + G +R + +F Sbjct: 225 QFGMMMNDECHLATGKSISSIISGLNNCMFKFGLSGSLRDGKANIMQY---VGMFGEIFK 281 Query: 229 -ATQTTKVEDLARISLRPGPLFINVVPE-----TDNSTADGLEQGYVVCDSDKRFLLLFS 282 T + +ED L+ +F+ E + + ++ + +K L Sbjct: 282 PVTTSKLMEDGQVTELKINSIFLRYPDEFTTKLKGKTYQEEIKIITGLSKRNKWIAKLAI 341 Query: 283 FLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGI 342 L + + ++F + K +L+ V + G+ + R N + I Sbjct: 342 KLAQKDENAFVMF-KHVSHGKAIFDLIKNEYDKVYYVSGEVDTETRNIMKTLAENGKGII 400 Query: 343 LICT-DVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGF 401 ++ + V + G+ + + ++ + +GR R K + ++ ++ G Sbjct: 401 IVASYGVFSTGISVKNLHHVVLAHGVKSKIIVLQTIGRVLRKHGSKTIATVWDLIDDAGV 460 Query: 402 LRYLKASKVP-LNEYEFPENKIANVQSQLEKLIKSNYYL 439 +K ++ ++ I +Q ++ K NY + Sbjct: 461 KPKSANTKKKYVHLNYLLKHGIDRIQRYADE--KFNYVM 497 >3B6E-A nrPDB Length = 216 Score = 64.2 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 33/142 (23%), Positives = 60/142 (42%), Gaps = 8/142 (5%) Query: 64 TMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPT 123 + Q P L G++++ TGSGKT + A + L K G +IV+ Sbjct: 33 QLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPG-KVIVLVNK 91 Query: 124 RELALQIF-GVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRL---LDHL 179 L Q+F + ++ + G+ G + +++K +++I+T L L +L Sbjct: 92 VLLVEQLFRKEFQPFLKKWYRVIGL-SGDTQLKISFPEVVKSCDIIISTAQILENSLLNL 150 Query: 180 QNT--KGFVFKNLKALIIDEAD 199 +N G + +IIDE Sbjct: 151 ENGEDAGVQLSDFSLIIIDECH 172 >6BOG-A nrPDB Length = 968 Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 3/115 (2%) Query: 274 DKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYI-DLPVLELHGKQKQQKRTNTF 332 D R L +L ++ +K++V + + ++L + H +R Sbjct: 488 DPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAA 547 Query: 333 FEFCNAE--RGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTK 385 F + +L+C+++ + G + ++ FD P +P R+GR R + Sbjct: 548 AWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQ 602 >5GM6-Y nrPDB Length = 876 Score = 63.9 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 69/424 (16%), Positives = 141/424 (33%), Gaps = 64/424 (15%) Query: 25 TSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQA---RTIPPLLAGRD 81 T+++++ PE + + L+ + + I++ + V + + + Sbjct: 184 TNEEDDLLPEEKLQYEARLAQALETEEKRILTIQEAR--KLLPVHQYKDELLQEIKKNQV 241 Query: 82 VLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFH 141 ++ +TGSGKT +P + L F + I + P R A VA + + Sbjct: 242 LIIMGETGSGKTT--QLP--QYLVEDGFTDQGKLQIAITQPRRVAA---TSVAARVADEM 294 Query: 142 SQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLL-DHLQNTKGFVFKNLKALIIDEAD- 199 + G +G R ++ K V + T G LL + L ++K ++IDEA Sbjct: 295 NVVLGKEVGYQIRFEDKTTPNKTV-LKYMTDGMLLREFLTDSK---LSKYSCIMIDEAHE 350 Query: 200 RILEIGFEDEMRQIIKILPNEDRQSMLFS-ATQTTKVEDLARIS---------LRPGPLF 249 R L + + ILP +L S AT + + R P+ Sbjct: 351 RTLATDIL--IGLLKDILPQRPTLKLLISSATM--NAKKFSEFFDNCPIFNVPGRRYPVD 406 Query: 250 INVVPETDNSTADG--LEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAE 307 I+ + + + + +L + + + + ++ Sbjct: 407 IHYTLQPEANYIHAAITTIFQIHTTQSLPGDILVFLTGQEEIE------RTKTKLEEIMS 460 Query: 308 LL--NYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWII--- 362 L + + ++ Q+++ F R +++ T++A L I + ++I Sbjct: 461 KLGSRTKQMIITPIYANLPQEQQLKIFQPTPENCRKVVLATNIAETSLTIDGIRYVIDPG 520 Query: 363 ----QFDPPDDPRDYI-----------HRVGRTARGTKGKGKSLMFLTPNELGFLRYLKA 407 P + R GR R GK F + +L L+ Sbjct: 521 FVKENSYVPSTGMTQLLTVPCSRASVDQRAGRAGRVGPGK----CFRIFTKWSYLHELEL 576 Query: 408 SKVP 411 P Sbjct: 577 MPKP 580 >4ON9-A nrPDB Length = 580 Score = 63.5 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 28/140 (20%), Positives = 52/140 (37%), Gaps = 8/140 (5%) Query: 64 TMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVIT-- 121 + Q P + G++ + A TG GKT L+ E + + G ++ Sbjct: 29 KPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLL-ICEHHLKKFPQGQKG-KVVFFANQ 86 Query: 122 -PTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 P E Q V + E H + G E++++ +++I TP L+++L+ Sbjct: 87 IPVYE---QQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLK 143 Query: 181 NTKGFVFKNLKALIIDEADR 200 +I DE Sbjct: 144 KGTIPSLSIFTLMIFDECHN 163 Score = 59.6 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 67/192 (34%), Gaps = 35/192 (18%) Query: 272 DSDKRFLLLFSFLKR----NQKKKIIVFLSSCNSVKYYAELLNYIDLP------VLELHG 321 + + + L L+ N + I+F+ + V + +L G Sbjct: 393 NENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRG 452 Query: 322 KQKQQK------RTNTFFEFC-NAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYI 374 K Q + F + + ILI T VA G+DI + +I ++ + I Sbjct: 453 KTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMI 512 Query: 375 HRVGRTARGTKGKGKSLMFLTPNELGFL----------RYLKASKVPLNEYEFP--ENKI 422 GR R K FL + G + + + S + L ++ KI Sbjct: 513 QTRGR-GRARGSK----CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKI 567 Query: 423 ANVQSQLEKLIK 434 ++Q+ EK I+ Sbjct: 568 LHIQTH-EKFIR 578 >6F4A-B nrPDB Length = 644 Score = 63.1 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 59/417 (14%), Positives = 126/417 (30%), Gaps = 88/417 (21%) Query: 22 EKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMG----------------FTTM 65 +K T K + + + + L+Q + ++ G F Sbjct: 95 KKITGKTEGVTKYEQFQYLLSSYYDCILNQEIIPSMLNTGTDDSVHSVDFSNPAEWFPEA 154 Query: 66 TSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRE 125 ++ I T SGKT +++ L + G P R Sbjct: 155 RKIRRHIIMH---------VGPTNSGKTFR----SLQKLKAADRGYYAG-------PLRL 194 Query: 126 LALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGF 185 LA +++ E + + ++ G ++ +++ N+ T ++ + + F Sbjct: 195 LAREVY----EKFKHENVRCNLLT-GEEVIKDLDEMGNEANLTSGT----IEMIPLNQNF 245 Query: 186 VFKNLKALIIDEADRI--LEIGFEDEMRQIIKILPNEDRQSMLF-SATQTTKVEDLARIS 242 +++DE + L+ G+ +L + ++ A+ ++ + Sbjct: 246 D-----VVVLDEIQMMADLDRGW----AWTNALLGAKAKEVHCCGEASTIPLIKKIVE-- 294 Query: 243 LRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSV 302 + L IN + L +K +V S + Sbjct: 295 MTGDKLTINEYERMGKLVVEE--------------EALTKGYHSLKKGDCVVAFSKKAIL 340 Query: 303 KYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWII 362 E+ +L ++G + R F + E ILI +D GL++ + Sbjct: 341 DLKLEIEKKTELKAAVIYGSLPPETRVKQANLFNSGEFDILIASDAIGMGLNLSIDRVVF 400 Query: 363 QF-------DPPDDPRDYIHRV-GRTARG-------TKGKGKSLMFLTPNELGFLRY 404 D D I ++ GR R + + + PN L +R Sbjct: 401 TTSKKFDGRDMVDMTSSAIKQIGGRAGRFKQNIHDNGELPVGYITAVKPNVLKAVRE 457 >5D0U-A nrPDB Length = 714 Score = 63.1 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 73/391 (18%), Positives = 131/391 (33%), Gaps = 68/391 (17%) Query: 82 VLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFH 141 ++ +TGSGKT IP L L + G I P R A+ VA+ + + Sbjct: 57 LVFVGETGSGKTT--QIPQYVLYDELPH--QTGKLIACTQPRRVAAM---SVAQRVADEL 109 Query: 142 SQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLL-DHLQNTKGFVFKNLKALIIDEAD- 199 G +G + R + K + T G+LL + + + +I+DEA Sbjct: 110 DVKLGEEVGYSIRFE--NKTSSKTLLKYMTDGQLLREAMHDR---DMSRYSCIILDEAHE 164 Query: 200 RILEIGFEDEMRQIIKILP--NEDRQSMLFSATQTTKVEDLARISL---------RPGPL 248 R L D + ++K L +D + ++ SAT + R P+ Sbjct: 165 RTLAT---DILMALLKQLSERRKDLKIIVMSATL--DAQKFQSYFFNAPLLAVPGRTHPV 219 Query: 249 FINVVPETDNSTADGLEQGYVVCDSDKRF-LLLFSFLKRNQKKKIIVFLSS-CNSVKYYA 306 I PE + + + + + + +L + + V Sbjct: 220 EIFYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDA---CRRISLEVDEMI 276 Query: 307 ELLNYIDLPVLELHGKQKQQKRTNTFFE----FCNAER---GILICTDVAARGLDIPAVD 359 + + V L+G ++ F + F R ++ T++A L I + Sbjct: 277 RESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIV 336 Query: 360 WII--------QFDP----------PDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGF 401 +++ ++P P R GR R GK F E F Sbjct: 337 YVVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGRTRPGK----CFRLYTEEAF 392 Query: 402 LRYLKASKVPLNEYEFPENKIANVQSQLEKL 432 + L P E + ++N +L+KL Sbjct: 393 KKELIEQTYP----EILRSNLSNTVLELKKL 419 >4BPB-A nrPDB Length = 698 Score = 63.1 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 28/140 (20%), Positives = 52/140 (37%), Gaps = 8/140 (5%) Query: 64 TMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVIT-- 121 + Q P + G++ + A TG GKT L+ E + + G ++ Sbjct: 13 KPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLL-ICEHHLKKFPQGQKG-KVVFFANQ 70 Query: 122 -PTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 P E Q V + E H + G E++++ +++I TP L+++L+ Sbjct: 71 IPVYE---QNKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLK 127 Query: 181 NTKGFVFKNLKALIIDEADR 200 +I DE Sbjct: 128 KGTIPSLSIFTLMIFDECHN 147 Score = 59.2 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 37/194 (19%), Positives = 67/194 (34%), Gaps = 37/194 (19%) Query: 272 DSDKRFLLLFSFLKR----NQKKKIIVFLSSCNSVKYYAELLNYIDLP------VLELHG 321 + + + L L+ N + I+F+ + V + +L G Sbjct: 377 NENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRG 436 Query: 322 KQKQQK--------RTNTFFEFC-NAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRD 372 K Q + F + + ILI T VA G+DI + +I ++ + Sbjct: 437 KTNQNTFFGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIK 496 Query: 373 YIHRVGRTARGTKGKGKSLMFLTPNELGFL----------RYLKASKVPLNEYEFP--EN 420 I GR R K FL + G + + + S + L ++ Sbjct: 497 MIQTRGR-GRARGSK----CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFRE 551 Query: 421 KIANVQSQLEKLIK 434 KI ++Q+ EK I+ Sbjct: 552 KILHIQTH-EKFIR 564 >4A2W-A nrPDB Length = 936 Score = 62.7 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 38/202 (18%), Positives = 69/202 (34%), Gaps = 20/202 (9%) Query: 11 DSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSV-- 68 D VD + T + E T E + LS+ A E +G V Sbjct: 189 DIREDNAKDVDSEMTDASEDCL-EASMTYSEEAEPDDNLSENLGSAAEGIG--KPPPVYE 245 Query: 69 -------QARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVIT 121 Q P + G++ L A TGSGKT ++ ++ + ++ + Sbjct: 246 TKKARSYQIELAQPAINGKNALICAPTGSGKTFVSILICEHHFQNMPAGRKA--KVVFLA 303 Query: 122 ---PTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDH 178 P E Q V + E + + G EK+++ ++++ TP L++ Sbjct: 304 TKVPVYE---QQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIEDSDIIVVTPQILVNS 360 Query: 179 LQNTKGFVFKNLKALIIDEADR 200 ++ +I DE Sbjct: 361 FEDGTLTSLSIFTLMIFDECHN 382 Score = 61.6 bits (148), Expect = 7e-10, Method: Composition-based stats. Identities = 32/218 (14%), Positives = 72/218 (33%), Gaps = 32/218 (14%) Query: 236 EDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVF 295 + L P I + + + T + + +VC +L + N + + ++F Sbjct: 588 QHLTAKFQEKEPELIAL---SKDETNENPKLEELVC-------ILDDAYRYNPQTRTLLF 637 Query: 296 LSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTN------------TFFEFCNAE-RGI 342 + V + + + G + R + F ++ + Sbjct: 638 AKTRALVSALKKCMEENPILNYIKPGVLMGRGRRDQTTGMTLPSQKGVLDAFKTSKDNRL 697 Query: 343 LICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMF----LTPNE 398 LI T VA G+DI + ++ ++ + I GR R K + + + Sbjct: 698 LIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGR-GRAAGSKCILVTSKTEVVENEK 756 Query: 399 LGFLRYLKASKV--PLNEYEFPE--NKIANVQSQLEKL 432 + +K + +++ KI N+Q + L Sbjct: 757 CNRYKEEMMNKAVEKIQKWDEETFAKKIHNLQMKERVL 794 >4A2Q-A nrPDB Length = 797 Score = 62.3 bits (150), Expect = 5e-10, Method: Composition-based stats. Identities = 38/202 (18%), Positives = 69/202 (34%), Gaps = 20/202 (9%) Query: 11 DSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSV-- 68 D VD + T + E T E + LS+ A E +G V Sbjct: 189 DIREDNAKDVDSEMTDASEDCL-EASMTYSEEAEPDDNLSENLGSAAEGIG--KPPPVYE 245 Query: 69 -------QARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVIT 121 Q P + G++ L A TGSGKT ++ ++ + ++ + Sbjct: 246 TKKARSYQIELAQPAINGKNALICAPTGSGKTFVSILICEHHFQNMPAGRKA--KVVFLA 303 Query: 122 ---PTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDH 178 P E Q V + E + + G EK+++ ++++ TP L++ Sbjct: 304 TKVPVYE---QQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIEDSDIIVVTPQILVNS 360 Query: 179 LQNTKGFVFKNLKALIIDEADR 200 ++ +I DE Sbjct: 361 FEDGTLTSLSIFTLMIFDECHN 382 Score = 61.6 bits (148), Expect = 9e-10, Method: Composition-based stats. Identities = 32/218 (14%), Positives = 72/218 (33%), Gaps = 32/218 (14%) Query: 236 EDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVF 295 + L P I + + + T + + +VC +L + N + + ++F Sbjct: 588 QHLTAKFQEKEPELIAL---SKDETNENPKLEELVC-------ILDDAYRYNPQTRTLLF 637 Query: 296 LSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTN------------TFFEFCNAE-RGI 342 + V + + + G + R + F ++ + Sbjct: 638 AKTRALVSALKKCMEENPILNYIKPGVLMGRGRRDQTTGMTLPSQKGVLDAFKTSKDNRL 697 Query: 343 LICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMF----LTPNE 398 LI T VA G+DI + ++ ++ + I GR R K + + + Sbjct: 698 LIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGR-GRAAGSKCILVTSKTEVVENEK 756 Query: 399 LGFLRYLKASKV--PLNEYEFPE--NKIANVQSQLEKL 432 + +K + +++ KI N+Q + L Sbjct: 757 CNRYKEEMMNKAVEKIQKWDEETFAKKIHNLQMKERVL 794 >5I8Q-A nrPDB Length = 767 Score = 62.3 bits (150), Expect = 5e-10, Method: Composition-based stats. Identities = 85/480 (17%), Positives = 151/480 (31%), Gaps = 81/480 (16%) Query: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLK----- 55 +A +K+ D +K E+ K++ T + Sbjct: 26 IAEELSKQHPLPSEEPLVHHDAGEFKGLQR---HHTSAEEAQKLEDGKINPFTGREFTPK 82 Query: 56 --AIEKMGFTTMTSVQARTIPPLLAGRDVLG-AAKTGSGKTLAFLIPAIELLHSLKFKPR 112 I K+ Q L ++ +TGSGKT IP L + Sbjct: 83 YVDILKIRRELPVHAQRDEFLKLYQNNQIMVFVGETGSGKTT--QIPQFVLFDEMPHLEN 140 Query: 113 NGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATP 172 T + P R A+ VA+ + E G + G + R E + K + + T Sbjct: 141 --TQVACTQPRRVAAM---SVAQRVAEEMDVKLGEEV-GYSIRFENKTSNKTI-LKYMTD 193 Query: 173 GRLL-DHLQNTKGFVFKNLKALIIDEADRI-----LEIGFEDEMRQIIKILPNEDRQSML 226 G LL + +++ +I+DEA + +G ++ + D + ++ Sbjct: 194 GMLLREAMEDH---DLSRYSCIILDEAHERTLATDILMGLLKQVVKR-----RPDLKIII 245 Query: 227 FSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKR 286 SAT E R PL E DS + Sbjct: 246 MSATL--DAEKFQRYF-NDAPLLAVPGRTYPVELYYTPEFQRDYLDSA--IRTVLQIHAT 300 Query: 287 NQKKKIIVFLSSCNSVKYYAELLNYID-----------LPVLELHGKQKQQKRTNTFF-- 333 + I++FL+ + ++ ++ L V L+G ++ F Sbjct: 301 EEAGDILLFLTGEDEIEDAVRKISLEGDQLVREEGCGPLSVYPLYGSLPPHQQQRIFEPA 360 Query: 334 -EFCNAE--RGILICTDVAARGLDIPAVDWIIQ--------FDP----------PDDPRD 372 E N R ++I T++A L I + +++ ++P P Sbjct: 361 PESHNGRPGRKVVISTNIAETSLTIDGIVYVVDPGFSKQKVYNPRIRVESLLVSPISKAS 420 Query: 373 YIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPENKIANVQSQLEKL 432 R GR R GK F E F + L P E + +++ +L+KL Sbjct: 421 AQQRAGRAGRTRPGK----CFRLYTEEAFQKELIEQSYP----EILRSNLSSTVLELKKL 472 >5XDR-A nrPDB Length = 690 Score = 60.4 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 82/442 (18%), Positives = 145/442 (32%), Gaps = 71/442 (16%) Query: 32 APEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMT-SVQARTIPPLLAGRDVLGAAKTGS 90 PE C+ F L + I K + R L+ + + +TGS Sbjct: 1 GPEFSLPQCINPFTNLPHTPRYYD-ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGS 59 Query: 91 GKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIG 150 GKT IP + ++ P G+ P R A+ VA+ + + G +G Sbjct: 60 GKTT--QIPQW-CVEYMRSLPGPKRGVACTQPRRVAAM---SVAQRVADEMDVMLGQEVG 113 Query: 151 GANRRQEAEKLMKGVNML-IATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDE 209 E +L T G LL N + + +I+DEA E + Sbjct: 114 ---YSIRFEDCSSAKTILKYMTDGMLLREAMNDP--LLERYGVIILDEAH---ERTLATD 165 Query: 210 MRQIIKILPNEDRQ-----SMLFSATQTT-------KVEDLARISLRPGPLFINVVPETD 257 + ++ +L RQ ++ SAT L I R P+ I PE + Sbjct: 166 I--LMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPE 223 Query: 258 NSTADG--LEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSS-CNSVKYYAELLNYIDL 314 + + ++ LL + + + V + D+ Sbjct: 224 RDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEA---CKRIKREVDDLGPEVG--DI 278 Query: 315 PVLELHGKQKQQKRTNTFF----EFCNAE--RGILICTDVAARGLDIPAVDWIIQ----- 363 ++ L+ Q++ F + N R +++ T++A L I V ++I Sbjct: 279 KIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAK 338 Query: 364 ---FDPPDDPRDYI----------HRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKV 410 ++P + R GR R GK F E + ++ + Sbjct: 339 QKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGK----CFRLYTEKAYKTEMQDNTY 394 Query: 411 PLNEYEFPENKIANVQSQLEKL 432 P E + + +V QL+KL Sbjct: 395 P----EILRSNLGSVVLQLKKL 412 >4A36-A nrPDB Length = 556 Score = 60.4 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 32/218 (14%), Positives = 72/218 (33%), Gaps = 32/218 (14%) Query: 236 EDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVF 295 + L P I + + + T + + +VC +L + N + + ++F Sbjct: 347 QHLTAKFQEKEPELIAL---SKDETNENPKLEELVC-------ILDDAYRYNPQTRTLLF 396 Query: 296 LSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTN------------TFFEFCNAE-RGI 342 + V + + + G + R + F ++ + Sbjct: 397 AKTRALVSALKKCMEENPILNYIKPGVLMGRGRRDQTTGMTLPSQKGVLDAFKTSKDNRL 456 Query: 343 LICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMF----LTPNE 398 LI T VA G+DI + ++ ++ + I GR R K + + + Sbjct: 457 LIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGR-GRAAGSKCILVTSKTEVVENEK 515 Query: 399 LGFLRYLKASKV--PLNEYEFPE--NKIANVQSQLEKL 432 + +K + +++ KI N+Q + L Sbjct: 516 CNRYKEEMMNKAVEKIQKWDEETFAKKIHNLQMKERVL 553 Score = 56.9 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 25/135 (18%), Positives = 51/135 (37%), Gaps = 8/135 (5%) Query: 69 QARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVIT---PTRE 125 Q P + G++ L A TGSGKT ++ ++ + ++ + P E Sbjct: 12 QIELAQPAINGKNALICAPTGSGKTFVSILICEHHFQNMPAGRKA--KVVFLATKVPVYE 69 Query: 126 LALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGF 185 Q V + E + + G EK+++ ++++ TP L++ ++ Sbjct: 70 ---QQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIEDSDIIVVTPQILVNSFEDGTLT 126 Query: 186 VFKNLKALIIDEADR 200 +I DE Sbjct: 127 SLSIFTLMIFDECHN 141 >4A4Z-A nrPDB Length = 997 Score = 60.0 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 53/260 (20%), Positives = 88/260 (33%), Gaps = 43/260 (16%) Query: 38 TTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLA-- 95 +E F+EL + F T Q + L G V AA T +GKT+ Sbjct: 19 NHKIENFDELIPNPA-----RSWPFELDT-FQKEAVYHLEQGDSVFVAAHTSAGKTVVAE 72 Query: 96 FLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRR 155 + I RN T I +P + L+ Q F +E F G++ G Sbjct: 73 YAIAM---------AHRNMTKTIYTSPIKALSNQKFRDFKET--FDDVNIGLITGDVQIN 121 Query: 156 QEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIK 215 +A L+ + L L ++++ +I DE + + ++I Sbjct: 122 PDANCLIMTTEI-------LRSMLYRGADL-IRDVEFVIFDEVHYVNDQDRGVVWEEVII 173 Query: 216 ILPNEDRQSMLFSATQTTKVEDLARISL--------------RPGPLFINVVPETDNSTA 261 +LP + +L SAT E A RP PL IN+ + + Sbjct: 174 MLPQHVKFILL-SATVPNTYE-FANWIGRTKQKNIYVISTPKRPVPLEINIWAKKELIPV 231 Query: 262 DGLEQGYVVCDSDKRFLLLF 281 ++ + K +L Sbjct: 232 INQNSEFLEANFRKHKEILN 251 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 30/203 (14%), Positives = 60/203 (29%), Gaps = 31/203 (15%) Query: 230 TQTTKVEDLARISLRPGPLFINVVPETDNST--ADGLEQGYVVCDSDKRFLLLFSFLKRN 287 T V L + L P +F+ + +G+ C++ ++ + Sbjct: 323 TWPEIVNYLRKRELLPMVVFVFSKKRCEEYADWLEGIN----FCNNKEKSQIHM------ 372 Query: 288 QKKKIIVFLSSCNSVKYYAELLNYIDLP---VLELHGKQKQQKRTNTFFEFCNAERGILI 344 +K I + ++L L + HG + F +L Sbjct: 373 FIEKSI--TRLKKEDRDLPQILKTRSLLERGIAVHHGGLLPIVKELIEILFSKGFIKVLF 430 Query: 345 CTDVAARGLDIPAVDWIIQFDPPD---------DPRDYIHRVGRTARGTK---GKGKSLM 392 T+ A GL++P +I P ++ GR R G + Sbjct: 431 ATETFAMGLNLPT-RTVIFSSIRKHDGNGLRELTPGEFTQMAGRAGRRGLDSTGTVIVMA 489 Query: 393 FLTPNELGFLRYLKASKVPLNEY 415 + +P + + + VP Sbjct: 490 YNSPLSIATFKEVTMG-VPTRLQ 511 >6ID1-V nrPDB Length = 795 Score = 59.6 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 74/399 (18%), Positives = 134/399 (33%), Gaps = 69/399 (17%) Query: 74 PPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGV 133 L+ + + +TGSGKT IP + ++ P G+ P R A+ V Sbjct: 148 DILVRHQSFVLVGETGSGKTT--QIPQW-CVEYMRSLPGPKRGVACTQPRRVAAM---SV 201 Query: 134 ARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNML-IATPGRLLDHLQNTKGFVFKNLKA 192 A+ + + G +G E +L T G LL N + + Sbjct: 202 AQRVADEMDVMLGQEVG---YSIRFEDCSSAKTILKYMTDGMLLREAMNDP--LLERYGV 256 Query: 193 LIIDEADRILEIGFEDEMRQIIKILPNEDRQ-----SMLFSATQTT-------KVEDLAR 240 +I+DEA E ++ ++ +L RQ ++ SAT L Sbjct: 257 IILDEAH---ERTLATDI--LMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLT 311 Query: 241 ISLRPGPLFINVVPETDNSTADG--LEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSS 298 I R P+ I PE + + + ++ LL + + + Sbjct: 312 IPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEA---CKR 368 Query: 299 -CNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFF----EFCNAE--RGILICTDVAAR 351 V + D+ ++ L+ Q++ F + N R +++ T++A Sbjct: 369 IKREVDDLGPEVG--DIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAET 426 Query: 352 GLDIPAVDWIIQ--------FDPPDDPRDYI----------HRVGRTARGTKGKGKSLMF 393 L I V ++I ++P + R GR R GK F Sbjct: 427 SLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGK----CF 482 Query: 394 LTPNELGFLRYLKASKVPLNEYEFPENKIANVQSQLEKL 432 E + ++ + P E + + +V QL+KL Sbjct: 483 RLYTEKAYKTEMQDNTYP----EILRSNLGSVVLQLKKL 517 >5FMF-1 nrPDB Length = 492 Score = 59.2 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 55/364 (15%), Positives = 107/364 (29%), Gaps = 61/364 (16%) Query: 66 TSVQARTIPPLLAG---RDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITP 122 Q +++ + R + G+GKTL + A + S +IV+ Sbjct: 70 RPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKS----------VIVLCT 119 Query: 123 TRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEK--LMKGVNMLIATPGRLLDHLQ 180 + +Q + + + + E ++ +M+ T R D + Sbjct: 120 SSVSVMQWRQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQK 179 Query: 181 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR 240 + +I+DE + F + I + +AT + + + Sbjct: 180 VMDFLTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAK------LGLTATLVREDDKIGD 233 Query: 241 ISLRPGPLF-------------INVVPETDNSTADGLEQGYVVCDSDKRFLLLFSF---- 283 ++ GP I V + E R +L Sbjct: 234 LNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPT 293 Query: 284 ----------LKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFF 333 + KIIVF ++V E + P ++G QQ+R N Sbjct: 294 KFQACQFLIQYHERRGDKIIVF---SDNVYALQEYALKMGKP--FIYGSTPQQERMNILQ 348 Query: 334 EFC-NAERGILICTDVAARGLDIPAVDWII----QFDPPDDPRDYIHRVGRTARGTKGKG 388 F N + + + V +D+P +I + R R+GR R + Sbjct: 349 NFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYG---SRRQEAQRLGRILRAKRRND 405 Query: 389 KSLM 392 + Sbjct: 406 EGFN 409 >4CBI-A nrPDB Length = 516 Score = 59.2 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 51/324 (15%), Positives = 97/324 (29%), Gaps = 61/324 (18%) Query: 88 TGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGI 147 TG+GKT IE + K ++V+ P R A ++ R+ + S F + Sbjct: 53 TGAGKTTELPRSVIEEIGRHK-------RVLVLIPLRAAAESVYQYMRQ--KHPSIAFNL 103 Query: 148 VIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFE 207 IG A + A+ G Q + +DE Sbjct: 104 RIGEMKEGDMATG------ITYASYGYFCQMSQPKLRAAMVEYSFIFLDEYHCAT----- 152 Query: 208 DEMRQIIKILPN--EDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLE 265 E I+ + E+ + + +AT V + + P+ + PE + L Sbjct: 153 PEQLAIMGKIHRFSENLRVVAMTATPAGTV----TTTGQKHPIEEFIAPE--VMKGEDLG 206 Query: 266 QGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQ 325 Y+ K K ++VF+ + N A+ L + Sbjct: 207 SEYLDIAGLK-------IPVEEMKNNMLVFVPTRNMAVEAAKKLKAKGYNSGYYYSG--- 256 Query: 326 QKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDP---------PD-------- 368 + + + +++ T+ G+ +P +D ++ P Sbjct: 257 -EDPSNLRVVTSQSPYVVVATNAIESGVTLPDLDVVVDTGLKCEKRIRLSPKMPFIVTGL 315 Query: 369 -----DPRDYIHRVGRTARGTKGK 387 + R GR R G+ Sbjct: 316 KRMAVTIGEQAQRRGRVGRVKPGR 339 >5WX1-A nrPDB Length = 733 Score = 58.9 bits (141), Expect = 5e-09, Method: Composition-based stats. Identities = 50/324 (15%), Positives = 96/324 (29%), Gaps = 61/324 (18%) Query: 88 TGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGI 147 TG+GKT IE + K ++V+ P R A ++ R+ + S F + Sbjct: 278 TGAGKTTELPRSVIEEIGRHK-------RVLVLIPLRAAAESVYQYMRQ--KHPSIAFNL 328 Query: 148 VIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFE 207 IG A + A+ G Q + +DE Sbjct: 329 RIGEMKEGDMATG------ITYASYGYFCQMPQPKLRAAMVEYSFIFLDEYHCAT----- 377 Query: 208 DEMRQIIKILPN--EDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLE 265 E I+ + E+ + + +AT V + + P+ + PE + L Sbjct: 378 PEQLAIMGKIHRFSENLRVVAMTATPAGTV----TTTGQKHPIEEFIAPE--VMKGEDLG 431 Query: 266 QGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQ 325 Y+ K K ++VF+ + N A+ L + Sbjct: 432 SEYLDIAGLK-------IPVEEMKSNMLVFVPTRNMAVETAKKLKAKGYNSGYYYSG--- 481 Query: 326 QKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFD-------------------- 365 + + + +++ T+ G+ +P +D ++ Sbjct: 482 -EDPSNLRVVTSQSPYVVVATNAIESGVTLPDLDVVVDTGLKCEKRIRLSSKMPFIVTGL 540 Query: 366 --PPDDPRDYIHRVGRTARGTKGK 387 + R GR R G+ Sbjct: 541 KRMAVTIGEQAQRRGRVGRVKPGR 564 >6HEG-A nrPDB Length = 809 Score = 58.5 bits (140), Expect = 7e-09, Method: Composition-based stats. Identities = 69/368 (18%), Positives = 128/368 (34%), Gaps = 79/368 (21%) Query: 73 IPPLLAGRD----VLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELAL 128 +P LL D VL +A TG+GK+ +P ++LL + II++ P R LA Sbjct: 10 LPELLTALDCAPQVLLSAPTGAGKST--WLP-LQLLAHPGINGK----IILLEP-RRLA- 60 Query: 129 QIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFK 188 VA+ L E ++ G +G R + + + + T G L +Q Sbjct: 61 -ARNVAQRLAELLNEKPGDTVG--YRMRAQNCVGPNTRLEVVTEGVLTRMIQRDP--ELS 115 Query: 189 NLKALIIDEADRIL-------------EIGFEDEMRQIIKILPNEDRQSMLFSATQTTKV 235 + +I+DE + G D++ + ++ SAT Sbjct: 116 GVGLVILDEFHERSLQADLALALLLDVQQGLRDDL------------KLLIMSATLDNDR 163 Query: 236 EDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSF----LKRNQKKK 291 L P+ I ++ + +E+ Y+ + +RF + + R + Sbjct: 164 LQ---QMLPEAPVVI-----SEGRSFP-VERRYLPLPAHQRFDDAVAVATAEMLRQESGS 214 Query: 292 IIVFLSSCNSVKYYAELLNYI---DLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDV 348 +++FL ++ E L D+ + L+G + R +++ T++ Sbjct: 215 LLLFLPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNI 274 Query: 349 AARGLDIPAVDWIIQ--------FDPPD----------DPRDYIHRVGRTARGTKGKGKS 390 A L I + ++ FDP R GR R G S Sbjct: 275 AETSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGR--LEPGIS 332 Query: 391 LMFLTPNE 398 L + + Sbjct: 333 LHLIAKEQ 340 >5SVA-Z nrPDB Length = 843 Score = 58.5 bits (140), Expect = 7e-09, Method: Composition-based stats. Identities = 55/364 (15%), Positives = 107/364 (29%), Gaps = 61/364 (16%) Query: 66 TSVQARTIPPLLAG---RDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITP 122 Q +++ + R + G+GKTL + A + S +IV+ Sbjct: 363 RPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKS----------VIVLCT 412 Query: 123 TRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEK--LMKGVNMLIATPGRLLDHLQ 180 + +Q + + + + E ++ +M+ T R D + Sbjct: 413 SSVSVMQWRQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQK 472 Query: 181 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR 240 + +I+DE + F + I + +AT + + + Sbjct: 473 VMDFLTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAK------LGLTATLVREDDKIGD 526 Query: 241 ISLRPGPLF-------------INVVPETDNSTADGLEQGYVVCDSDKRFLLLFSF---- 283 ++ GP I V + E R +L Sbjct: 527 LNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPT 586 Query: 284 ----------LKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFF 333 + KIIVF ++V E + P ++G QQ+R N Sbjct: 587 KFQACQFLIQYHERRGDKIIVF---SDNVYALQEYALKMGKP--FIYGSTPQQERMNILQ 641 Query: 334 EFC-NAERGILICTDVAARGLDIPAVDWII----QFDPPDDPRDYIHRVGRTARGTKGKG 388 F N + + + V +D+P +I + R R+GR R + Sbjct: 642 NFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYG---SRRQEAQRLGRILRAKRRND 698 Query: 389 KSLM 392 + Sbjct: 699 EGFN 702 >5WSO-A nrPDB Length = 476 Score = 56.5 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 52/324 (16%), Positives = 97/324 (29%), Gaps = 61/324 (18%) Query: 88 TGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGI 147 TG+GKT IE + K ++V+ P R A ++ R ++ S +F + Sbjct: 21 TGAGKTTELPKAVIEEIGRHK-------RVLVLIPLRAAAESVYQYMR--LKHPSISFNL 71 Query: 148 VIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFE 207 IG A + A+ G Q + +DE Sbjct: 72 RIGDMKEGDMATG------ITYASYGYFCQMPQPKLRAAMVEYSYIFLDEYHCAT----- 120 Query: 208 DEMRQIIKILPN--EDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLE 265 E II + E + + +AT V + + P+ + PE G Sbjct: 121 PEQLAIIGKIHRFSESIRVVAMTATPAGSV----TTTGQKHPIEEFIAPEVMKGEDLG-S 175 Query: 266 QGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQ 325 Q + L + + ++VF+ + N A+ L + Sbjct: 176 QFLDIAG-------LKIPVDEMKGN-MLVFVPTRNMAVEVAKKLKAKGYNSGYYYSG--- 224 Query: 326 QKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPR-------------- 371 + + +++ T+ G+ +P +D +I + R Sbjct: 225 -EDPANLRVVTSQSPYVIVATNAIESGVTLPDLDTVIDTGLKCEKRVRVSSKIPFIVTGL 283 Query: 372 --------DYIHRVGRTARGTKGK 387 + R GR R G+ Sbjct: 284 KRMAVTVGEQAQRRGRVGRVKPGR 307 >6I3O-A nrPDB Length = 677 Score = 55.0 bits (131), Expect = 8e-08, Method: Composition-based stats. Identities = 63/397 (15%), Positives = 117/397 (29%), Gaps = 85/397 (21%) Query: 71 RTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQI 130 + I + + ++ +TGSGKT + + + G P R A+ + Sbjct: 20 QIIQAVKDNQILIVVGETGSGKT-----TQVTQYLAEAGFTKYGMIG-CTQPRRVAAVSV 73 Query: 131 FG-VARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKN 189 VA E+ Q G I + A K+ T G L + K Sbjct: 74 AKRVAEEVGCQLGQEVGYTIRFEDVTSPATKIK------YMTDGMLQREILMDP--DLKR 125 Query: 190 LKALIIDEADRILEIGFEDEMRQIIKIL------PNEDRQSMLFSATQTTKVEDLARIS- 242 +++DEA ++ L D + ++ SAT E + Sbjct: 126 YSVIMLDEAHE------RTIATDVLFALLKKTVKRRPDLKVIVTSATL--DAEKFSEYFN 177 Query: 243 --------LRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIV 294 R P+ I E + + + I+V Sbjct: 178 SCPIFTIPGRTFPVEILYSREPEPDYLEAA------------LTTVMQIHLTEPPGDILV 225 Query: 295 FLSSCNS----VKYYAELLNYIDLPV-----LELHGKQKQQKRTNTFFEFCNAERGILIC 345 FL+ + E + + V L ++ + ++ F R ++I Sbjct: 226 FLTGQEEIDTACEILYERMKALGPSVPELIILPIYSALPSEMQSRIFEPAPPGSRKVVIA 285 Query: 346 TDVAARGLDIPAVDWIIQ--------FDP----------PDDPRDYIHRVGRTARGTKGK 387 T++A + I + +++ +DP P R GR R GK Sbjct: 286 TNIAETSITIDYIYYVVDPGFVKQNAYDPKLGMDSLVVTPISQAQANQRAGRAGRTGPGK 345 Query: 388 GKSLMFLTPNELGFLRYLKASKVPLNEYEFPENKIAN 424 F E + + + +P + +AN Sbjct: 346 ----CFRLYTEAAYQSEMLPTTIP----DIQRQNLAN 374 >4OK6-A nrPDB Length = 464 Score = 54.6 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 36/267 (13%), Positives = 71/267 (26%), Gaps = 53/267 (19%) Query: 86 AKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTF 145 A TGSGK+ G ++V+ P+ + F + Sbjct: 38 APTGSGKS----------TKVPAAYAAQGYKVLVLNPS----------VAATLGFGAYMS 77 Query: 146 GIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIG 205 N R + G + +T G+ L + G +I DE Sbjct: 78 KAHGVDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGAY----DIIICDECHSTDATS 133 Query: 206 FEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLE 265 + + R +L +AT V + +E Sbjct: 134 ILGIGTVLDQAETAGARLVVLATATPPGSV----------------------TVSHPNIE 171 Query: 266 QGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQ 325 + + + F L+ + + ++F S A L + + + + Sbjct: 172 EVALSTTGEIPFYGKAIPLEVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYRGLDV 231 Query: 326 QKRTNTFFEFCNAERGILICTDVAARG 352 N + +++ TD G Sbjct: 232 SVIPT------NGDV-VVVSTDALMTG 251 >4B6E-A nrPDB Length = 683 Score = 54.2 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 35/267 (13%), Positives = 71/267 (26%), Gaps = 53/267 (19%) Query: 86 AKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTF 145 A TGSGK+ G ++V+ P+ G + + H Sbjct: 239 APTGSGKS----------TKVPAAYAAQGYKVLVLNPS---VAATLGFGAYMSKAHGIDP 285 Query: 146 GIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIG 205 I G + G + +T G+ L + G +I DE Sbjct: 286 NIRTG-------VRTITTGAPVTYSTYGKFLADGGCSGGAY----DIIICDECHSTDSTT 334 Query: 206 FEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLE 265 + + R +L +AT V +E Sbjct: 335 ILGIGTVLDQAETAGARLVVLATATPPGSV----------------------TVPHPNIE 372 Query: 266 QGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQ 325 + + + F ++ + + ++F S A L+ + + + + Sbjct: 373 EVALSNTGEIPFYGKAIPIEAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRGLDV 432 Query: 326 QKRTNTFFEFCNAERGILICTDVAARG 352 + +++ TD G Sbjct: 433 SVIPTI------GDV-VVVATDALMTG 452 >4XGT-A nrPDB Length = 993 Score = 53.8 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 62/433 (14%), Positives = 119/433 (27%), Gaps = 125/433 (28%) Query: 67 SVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTREL 126 QA ++ + VL +A T +GKT+ + L + +I +P + L Sbjct: 70 PFQALSVASIEREESVLVSAHTSAGKTVVAEYAIAQCL-------KKNQRVIYTSPIKAL 122 Query: 127 ALQIF-GVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGF 185 + Q + E + G++ G A L+ + L + Sbjct: 123 SNQKYRDFQAEFGD-----VGLMTGDVTINPTASCLVMTTEI--------LRSMLYRGSE 169 Query: 186 VFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSAT------QTTKVEDLA 239 + + + ++ DE + + + I +LP++ R L SAT + + Sbjct: 170 IMREVAWVVFDEIHYMRDKIRGVVWEETIILLPDKVRYVFL-SATIPNAFQFAEWIAKIH 228 Query: 240 RIS-------LRPGPL-----------FINVVPETDNSTADGLEQGYVVCDSDKRFL--- 278 R + RP PL + +V E N + Q + + K Sbjct: 229 RQACHVVYTDFRPTPLQNYFFPAGGKGILLIVDEKGNFKENNFNQAMAMIEEKKGTDSND 288 Query: 279 ----------------------------LLFSFLKRNQKKKIIVFLSSCNSVKYYAELLN 310 + + + + +IVF S + A + Sbjct: 289 WSAKQKGKGKNKKTNKGGEAADEKADIAKIIKMILKKNFQPVIVFNFSKRECEQMALASS 348 Query: 311 YIDLPV---------------------------------------LELHGKQKQQKRTNT 331 + H + Sbjct: 349 SMKFNAPDEENMVNKVFENALASLSEDDKNLPQISNILPLLRKGIGVHHSGLLPILKETI 408 Query: 332 FFEFCNAERGILICTDVAARGLDIPAVDWII--------QFDPPDDPRDYIHRVGRTARG 383 F +L T+ + GL++PA + Q P +YI GR R Sbjct: 409 EILFQEGLIKVLFATETFSIGLNMPARTVVFTQVTKWDGQQRRPLTSSEYIQMAGRAGRR 468 Query: 384 TK-GKGKSLMFLT 395 +G +M + Sbjct: 469 GLDDRGIVIMMVD 481 >6FA9-A nrPDB Length = 655 Score = 53.8 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 71/396 (17%), Positives = 122/396 (30%), Gaps = 68/396 (17%) Query: 73 IPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQI-F 131 + + + ++ +TGSGKT IP + I P R A+ + Sbjct: 41 LDAVKEYQVLILVGETGSGKTT--QIP---QYLHEAGYTKGNRKIACTQPRRVAAMSVAA 95 Query: 132 GVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLK 191 VA E+ G I + E L T G LL + + + Sbjct: 96 RVADEMGVRLGHEVGYSIRFEDCTSEKTILK------YMTDGMLLREMVTSP--DLADYS 147 Query: 192 ALIIDEADRILEIGFEDEMRQIIKILP--NEDRQSMLFSATQTTKVEDLARISLRPGPLF 249 ++IDEA D + +IK L + + ++ SAT E + P+F Sbjct: 148 CIMIDEAHE--RTVHTDILLALIKDLTRARPELRLIISSATL--NAEKFS-AYFDDAPIF 202 Query: 250 INVVPETDNSTADGLEQGYVVCDSDKRFL----LLFSFLKRNQKKKIIVFL-------SS 298 +E Y +F + I+VFL + Sbjct: 203 ------NVPGRVHPVEVYYTSAPESNYLEAALVTVFQIHATQPEGDILVFLTGQEEIERA 256 Query: 299 CNSVKYYAELLNYI--DLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIP 356 C V+ L ++ L ++ + + F R ++ T++A L I Sbjct: 257 CERVEEIRRKLGKRVPEIIALPIYSNMPSEMQAKIFEPTPPGARKVVFSTNIAETSLTID 316 Query: 357 AVDWIIQFD--------------------PPDDPRDYIHRVGRTARGTKGKGKSLMFLTP 396 + ++I P R+GR R GK F Sbjct: 317 GIVYVIDSGYVKENTFSPVGTTGQSTLAVVPCSRAAANQRMGRAGRVKPGK----CFRLY 372 Query: 397 NELGFLRYLKASKVPLNEYEFPENKIANVQSQLEKL 432 + +L + S P E +++V QL+ L Sbjct: 373 TKYAYLSEMDESPTP----EIQRTSLSSVVLQLKAL 404 >3BXZ-A nrPDB Length = 471 Score = 53.8 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 57/294 (19%), Positives = 99/294 (33%), Gaps = 38/294 (12%) Query: 82 VLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFH 141 + +TG GKTL +PA L++L G G+ V+T LA + R L EF Sbjct: 100 CIAEMRTGEGKTLTATLPA--YLNAL-----TGKGVHVVTVNDYLAQRDAENNRPLFEFL 152 Query: 142 SQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRL-LDHLQNTKGFVF-----KNLKALII 195 T GI + G + E ++ T D+L++ F + L ++ Sbjct: 153 GLTVGINLPGMPAPAKREA--YAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALV 210 Query: 196 DEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPE 255 DE D IL DE R ++ + Q++ S T +++ G Sbjct: 211 DEVDSIL----IDEART--PLIISGANQTL-ASITFQNYFRLYEKLAGMTGTADTEAFEF 263 Query: 256 TDNSTADGLEQ------------GYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSS--CNS 301 + D + V ++ + +K K V + + Sbjct: 264 SSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEK 323 Query: 302 VKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDI 355 + + L + L+ K + + I T++A RG DI Sbjct: 324 SELVSNELTKAGIKHNVLNAKFHANEAAIVAQA--GYPAAVTIATNMAGRGTDI 375 >2ZJO-A nrPDB Length = 482 Score = 52.7 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 33/267 (12%), Positives = 71/267 (26%), Gaps = 53/267 (19%) Query: 86 AKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTF 145 A TGSGK+ G ++V+ P+ + F + Sbjct: 49 APTGSGKS----------TKVPAAYAAQGYKVLVLNPS----------VAATLGFGAYMS 88 Query: 146 GIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIG 205 N R + G + +T G+ L + G ++ DE Sbjct: 89 KAHGVDPNIRTGVRTITTGAPITYSTYGKFLADGGCSGGAY----DIIMCDECHSTDSTT 144 Query: 206 FEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLE 265 + + R +L +AT V +E Sbjct: 145 ILGIGTVLDQAETAGARLVVLATATPPGSV----------------------TVPHPNIE 182 Query: 266 QGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQ 325 + + + F ++ + + ++F S A L+ + + + + Sbjct: 183 EIALSNTGEIPFYGKAIPIETIKGGRHLIFCHSKKKCDELAAKLSALGIHAVAYYRGLDV 242 Query: 326 QKRTNTFFEFCNAERGILICTDVAARG 352 + + +++ TD G Sbjct: 243 ----SVIPA--SGNV-VVVATDALMTG 262 >6FTX-W nrPDB Length = 878 Score = 52.3 bits (124), Expect = 5e-07, Method: Composition-based stats. Identities = 24/164 (14%), Positives = 61/164 (37%), Gaps = 13/164 (7%) Query: 262 DGLEQGYVVCD--------SDKRFLLLFSFLKRNQKK--KIIVFLSSCNSVKYYAELLNY 311 + + Q ++ + S + +LL L R +K ++++F + + L+ Sbjct: 479 ERVLQKFMTRENVLRGLIMSSGKMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSI 538 Query: 312 IDLPVLELHGKQKQQKRTNTFFEFCNAERG---ILICTDVAARGLDIPAVDWIIQFDPPD 368 + L G +R + F + + L+ T G+++ D ++ FD Sbjct: 539 KGINFQRLDGTVPSAQRRISIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDW 598 Query: 369 DPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPL 412 +P+ + + R R + + L + L+ ++ + Sbjct: 599 NPQADLQAMARAHRIGQKNHVMVYRLVSKDTVEEEVLERARKKM 642 >5K8T-A nrPDB Length = 458 Score = 51.9 bits (123), Expect = 7e-07, Method: Composition-based stats. Identities = 51/328 (15%), Positives = 98/328 (29%), Gaps = 74/328 (22%) Query: 89 GSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVAREL-MEFHSQTFGI 147 G+GKT ++P I + +++ PTR +A ++ R L + + + + Sbjct: 34 GAGKTRR-VLPEIVR-----EAIKTRLRTVILAPTRVVAAEMEEALRGLPVRYMTTAVNV 87 Query: 148 VIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEAD-----RIL 202 G + + RLL + N I+DEA I Sbjct: 88 THSGTEIVDLM------CHATFTS--RLL------QPIRVPNYNLYIMDEAHFTDPSSIA 133 Query: 203 EIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTAD 262 G+ I + + ++ +AT + + + V +S D Sbjct: 134 ARGY------ISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEVPERAWSSGFD 187 Query: 263 GLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGK 322 + + K + F+ S + A L V++L K Sbjct: 188 WVT---------------------DHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRK 226 Query: 323 QKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWI--------IQFD--------- 365 + + F + + E ++ TD++ G + A I + D Sbjct: 227 TFETE----FQKTKHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGP 282 Query: 366 PPDDPRDYIHRVGRTARGTKGKGKSLMF 393 P R GR R G ++ Sbjct: 283 MPVTHASAAQRRGRIGRNPNKPGDEYLY 310 >5IY9-V nrPDB Length = 782 Score = 51.9 bits (123), Expect = 7e-07, Method: Composition-based stats. Identities = 74/453 (16%), Positives = 143/453 (31%), Gaps = 103/453 (22%) Query: 4 PSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFE-ELKLSQPTLKAIEKMGF 62 PS R D + + +D +Q + E E+ T FE + ++ + K + + Sbjct: 230 PSTSRVTDPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEY 289 Query: 63 T--------------------TMTSV----QARTIPPLLAG---RDVLGAAKTGSGKTLA 95 T+V Q +++ + R + G+GK+L Sbjct: 290 PLLAEYDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLV 349 Query: 96 FLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRR 155 + A + +V+ + A+ + + + + + Sbjct: 350 GVTAACTVRKR----------CLVLGNS---AVSVEQWKAQFKMWSTIDDSQIC---RFT 393 Query: 156 QEAEKLMKGVNMLIAT-------------PGRLLDHLQNTKGFVFKNLKALIIDEADRIL 202 +A+ G ++ I+T R+++ L+ + +I+DE I Sbjct: 394 SDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLK------TQEWGLMILDEVHTIP 447 Query: 203 EIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPL-------------F 249 F + + + +AT + + + ++ GP + Sbjct: 448 AKMFRRVLTIVQAHCK------LGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGY 501 Query: 250 INVVPETDNSTADGLEQG--YVVCDSDKR---------FLLLFSFL---KRNQKKKIIVF 295 I V + E YV + KR FL + KIIVF Sbjct: 502 IAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVF 561 Query: 296 LSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFC-NAERGILICTDVAARGLD 354 + ++K YA LN ++G Q +R F N + + + V D Sbjct: 562 ADNVFALKEYAIRLNKP-----YIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFD 616 Query: 355 IPAVDWIIQFDP-PDDPRDYIHRVGRTARGTKG 386 +P + +IQ R R+GR R KG Sbjct: 617 LPEANVLIQISSHGGSRRQEAQRLGRVLRAKKG 649 >3MWY-W nrPDB Length = 800 Score = 51.9 bits (123), Expect = 7e-07, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 55/145 (37%), Gaps = 5/145 (3%) Query: 273 SDKRFLLLFSFLKRNQKK--KIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTN 330 S + +LL L R +K ++++F + + L+ + L G +R Sbjct: 554 SSGKMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRI 613 Query: 331 TFFEFCNAERG---ILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGK 387 + F + + L+ T G+++ D ++ FD +P+ + + R R + Sbjct: 614 SIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKN 673 Query: 388 GKSLMFLTPNELGFLRYLKASKVPL 412 + L + L+ ++ + Sbjct: 674 HVMVYRLVSKDTVEEEVLERARKKM 698 >5OQJ-7 nrPDB Length = 843 Score = 51.2 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 38/233 (16%), Positives = 68/233 (29%), Gaps = 46/233 (19%) Query: 192 ALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLF-- 249 +I+DE + F + I + +AT + + + ++ GP Sbjct: 484 FIILDEVHVVPAAMFRRVVSTIAAHAK------LGLTATLVREDDKIGDLNFLIGPKLYE 537 Query: 250 -----------INVVPETDNSTADGLEQGYVVCDSDKRFLLLFSF--------------L 284 I V + E R +L Sbjct: 538 ANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQY 597 Query: 285 KRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFC-NAERGIL 343 + KIIVF ++V E + P ++G QQ+R N F N + + Sbjct: 598 HERRGDKIIVF---SDNVYALQEYALKMGKP--FIYGSTPQQERMNILQNFQYNDQINTI 652 Query: 344 ICTDVAARGLDIPAVDWII----QFDPPDDPRDYIHRVGRTARGTKGKGKSLM 392 + V +D+P +I + R R+GR R + + Sbjct: 653 FLSKVGDTSIDLPEATCLIQISSHYG---SRRQEAQRLGRILRAKRRNDEGFN 702 >2QEQ-A nrPDB Length = 434 Score = 51.2 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 59/375 (15%), Positives = 110/375 (29%), Gaps = 85/375 (22%) Query: 89 GSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIV 148 G+GKT + + R V+ PTR VA E+ E Sbjct: 12 GAGKTRR----ILPQIIKEAINRR--LRTAVLAPTR-------VVAAEMAEALR------ 52 Query: 149 IGGANRRQEAEKLMK---GVNML-IATPGRLLDHLQNTKGFVFKNLKALIIDEAD----- 199 G R + + + G ++ + L L + N ++DEA Sbjct: 53 --GLPIRYQTSAVAREHNGNEIVDVMCHATLTHRLMSPHRV--PNYNLFVMDEAHFTDPA 108 Query: 200 RILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNS 259 I G+ I + + ++ +AT + + L + NS Sbjct: 109 SIAARGY------ISTRVELGEAAAIFMTATPPGTSDPFPESNAPISDLQTEIPDRAWNS 162 Query: 260 TADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLEL 319 + + + K + F+ S A L V++L Sbjct: 163 GYEWITEY---------------------IGKTVWFVPSVKMGNEIALCLQRAGKKVIQL 201 Query: 320 HGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWI-----------------I 362 + K + + + + N + ++ TD++ G + A I + Sbjct: 202 NRKSYETE----YPKCKNDDWDFVVTTDISEMGANFKASRVIDSRKSVKPTIITEGEGRV 257 Query: 363 QFDPPD--DPRDYIHRVGRTARGTKGKGKSLMFL--TPNELGFLRYLKASKVPLNEYEFP 418 P R GRT R G + T + + +++ L+ P Sbjct: 258 ILGEPSAVTAASAAQRRGRTGRNPSQAGDEYCYGGHTNEDDSNCAHWTEARIMLDNINMP 317 Query: 419 ENKIA-NVQSQLEKL 432 IA Q + EK+ Sbjct: 318 NGLIAQFYQPEREKV 332 >6NMI-A nrPDB Length = 653 Score = 51.2 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 47/243 (19%), Positives = 80/243 (32%), Gaps = 46/243 (18%) Query: 173 GRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQT 232 R+++ L+ + +I+DE I F + + + +AT Sbjct: 347 ERVMEWLK------TQEWGLMILDEVHTIPAKMFRRVLTIVQAHCK------LGLTATLV 394 Query: 233 TKVEDLARISLRPGPL-------------FINVVPETDNSTADGLEQG--YVVCDSDKR- 276 + + + ++ GP +I V + E YV + KR Sbjct: 395 REDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRI 454 Query: 277 --------FLLLFSFL---KRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQ 325 FL + KIIVF + ++K YA LN ++G Q Sbjct: 455 LLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKP-----YIYGPTSQ 509 Query: 326 QKRTNTFFEFC-NAERGILICTDVAARGLDIPAVDWIIQFDP-PDDPRDYIHRVGRTARG 383 +R F N + + + V D+P + +IQ R R+GR R Sbjct: 510 GERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRA 569 Query: 384 TKG 386 KG Sbjct: 570 KKG 572 >5OF4-A nrPDB Length = 553 Score = 51.2 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 47/243 (19%), Positives = 80/243 (32%), Gaps = 46/243 (18%) Query: 173 GRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQT 232 R+++ L+ + +I+DE I F + + + +AT Sbjct: 195 ERVMEWLK------TQEWGLMILDEVHTIPAKMFRRVLTIVQAHCK------LGLTATLV 242 Query: 233 TKVEDLARISLRPGPL-------------FINVVPETDNSTADGLEQG--YVVCDSDKR- 276 + + + ++ GP +I V + E YV + KR Sbjct: 243 REDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRI 302 Query: 277 --------FLLLFSFL---KRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQ 325 FL + KIIVF + ++K YA LN ++G Q Sbjct: 303 LLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKP-----YIYGPTSQ 357 Query: 326 QKRTNTFFEFC-NAERGILICTDVAARGLDIPAVDWIIQFDP-PDDPRDYIHRVGRTARG 383 +R F N + + + V D+P + +IQ R R+GR R Sbjct: 358 GERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRA 417 Query: 384 TKG 386 KG Sbjct: 418 KKG 420 >5HZR-A nrPDB Length = 732 Score = 50.8 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 31/176 (17%), Positives = 64/176 (36%), Gaps = 5/176 (2%) Query: 243 LRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFL--KRNQKKKIIVFLSSCN 300 LR V E +N ++ + +F LL L + ++++F Sbjct: 397 LRKLCNHPFVFDEVENQMNPANVSNDLLWRTAGKFELLDRILPKYKATGHRVLMFFQMTA 456 Query: 301 SVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERG---ILICTDVAARGLDIPA 357 + + L + L L L G K + R+ +F + L+ T GL++ Sbjct: 457 IMDIMEDFLRFRGLHYLRLDGTTKSEDRSELLRQFNQPDSPYFMFLLSTRAGGLGLNLQT 516 Query: 358 VDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLN 413 D +I +D +P + R R + ++ L + + L+ ++ L+ Sbjct: 517 ADTVIIYDSDWNPHQDLQAQDRAHRIGQKNEVRILRLISSASVEEKILERARFKLD 572 >5X0Y-O nrPDB Length = 735 Score = 50.8 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 56/155 (36%), Gaps = 5/155 (3%) Query: 243 LRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQ--KKKIIVFLSSCN 300 L+ V E ++ E + +F LL L + + ++++F Sbjct: 390 LKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQ 449 Query: 301 SVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGIL---ICTDVAARGLDIPA 357 + + L YI++ L L G K +R+ F + L + T GL++ Sbjct: 450 IMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQT 509 Query: 358 VDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLM 392 D +I FD +P + R R + ++ Sbjct: 510 ADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRIL 544 >5WDX-A nrPDB Length = 649 Score = 50.8 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 39/267 (14%), Positives = 74/267 (27%), Gaps = 53/267 (19%) Query: 86 AKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTF 145 A TGSGK+ G ++V+ P+ G L + H Sbjct: 222 APTGSGKS----------TKVPVAYAAQGYKVLVLNPS---VAATLGFGAYLSKAHGINP 268 Query: 146 GIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIG 205 I G +M G + +T G+ L G +I DE + Sbjct: 269 NIRTG-------VRTVMTGEAITYSTYGKFLADGGCASGAY----DIIICDECHAVDATS 317 Query: 206 FEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLE 265 + + R ++L +AT V + +E Sbjct: 318 ILGIGTVLDQAETAGVRLTVLATATPPGSV----------------------TTPHPDIE 355 Query: 266 QGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQ 325 + + + + F L + + ++F S A L + L + + Sbjct: 356 EVGLGREGEIPFYGRAIPLSCIKGGRHLIFCHSKKKCDELAAALRGMGLNAVAYYRGLDV 415 Query: 326 QKRTNTFFEFCNAERGILICTDVAARG 352 + + +++ TD G Sbjct: 416 ----SIIPA--QGDV-VVVATDALMTG 435 >1YKS-A nrPDB Length = 440 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 58/342 (16%), Positives = 104/342 (30%), Gaps = 77/342 (22%) Query: 89 GSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIV 148 G+GKT F +P I L R +V+ PTR + L A ++ T Sbjct: 18 GAGKTRRF-LPQI-----LAECARRRLRTLVLAPTR-VVLSEMKEAFHGLDVKFHTQAFS 70 Query: 149 IGGANRRQEAEKLMKGVNMLIAT-------PGRLLDHLQNTKGFVFKNLKALIIDEADRI 201 G+ R E + + AT P R+++ + +I+DEA Sbjct: 71 AHGSGR----EVIDAMCH---ATLTYRMLEPTRVVNW------------EVIIMDEAH-F 110 Query: 202 LEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTA 261 L+ + ++L +AT ++ + + ++ E N+ Sbjct: 111 LDPASIAARGWAAHRARANESATILMTATPPGTSDEFPHSNGEIEDVQTDIPSEPWNTGH 170 Query: 262 DGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHG 321 D + +DKR FL S + A L V+ L+ Sbjct: 171 DWI-------LADKR--------------PTAWFLPSIRAANVMAASLRKAGKSVVVLNR 209 Query: 322 KQKQQKRTNTFFEFCNAERGILICTDVAARGLD--IPAV---------------DWIIQF 364 K +++ + ++ TD+A G + + V + Sbjct: 210 KTFEREYPTI----KQKKPDFILATDIAEMGANLCVERVLDCRTAFKPVLVDEGRKVAIK 265 Query: 365 DPPD-DPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYL 405 P R GR R G S + P ++ Sbjct: 266 GPLRISASSAAQRRGRIGRNPNRDGDSYYYSEPTSENNAHHV 307 >5JXT-B nrPDB Length = 349 Score = 50.0 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 21/144 (14%), Positives = 52/144 (36%), Gaps = 5/144 (3%) Query: 276 RFLLLFSFLKR--NQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFF 333 + ++L LKR Q ++++F + + + + G + R Sbjct: 86 KMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYKYCRIDGSTAHEDRIAAID 145 Query: 334 EFC---NAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKS 390 E+ + + L+ T G+++ D +I +D +P+ + + R R + K Sbjct: 146 EYNKPGSDKFIFLLTTRAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQTKQVV 205 Query: 391 LMFLTPNELGFLRYLKASKVPLNE 414 + + + L+ + L Sbjct: 206 VYRFVTDNAIEEKVLERAAQKLRL 229 >5JXR-A nrPDB Length = 723 Score = 50.0 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 21/144 (14%), Positives = 52/144 (36%), Gaps = 5/144 (3%) Query: 276 RFLLLFSFLKR--NQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFF 333 + ++L LKR Q ++++F + + + + G + R Sbjct: 411 KMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYKYCRIDGSTAHEDRIAAID 470 Query: 334 EFC---NAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKS 390 E+ + + L+ T G+++ D +I +D +P+ + + R R + K Sbjct: 471 EYNKPGSDKFIFLLTTRAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQTKQVV 530 Query: 391 LMFLTPNELGFLRYLKASKVPLNE 414 + + + L+ + L Sbjct: 531 VYRFVTDNAIEEKVLERAAQKLRL 554 Score = 28.4 bits (62), Expect = 8.4, Method: Composition-based stats. Identities = 33/148 (22%), Positives = 60/148 (40%), Gaps = 21/148 (14%) Query: 89 GSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIV 148 G GKTL I + L + G +V P L RE ++ + +V Sbjct: 134 GLGKTLQ-TIAFLGYLRHI--MGITGPH-LVTVPKSTL----DNWKREFEKWTPEVNVLV 185 Query: 149 IGGA-NRRQEA---EKLMKGVNMLIATPGRLLDHLQNTKGFVFKNL-KALIIDEADRILE 203 + GA R + + + ++ I + + + K + K + +IIDEA RI Sbjct: 186 LQGAKEERHQLINDRLVDENFDVCITS----YEMILREKAHLKKFAWEYIIIDEAHRIKN 241 Query: 204 IGFEDEMRQIIKILPNEDRQSMLFSATQ 231 E + Q+I++ + +R +L + T Sbjct: 242 E--ESSLAQVIRMFNSRNR--LLITGTP 265 >3RC8-A nrPDB Length = 677 Score = 49.6 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 31/190 (16%), Positives = 60/190 (31%), Gaps = 22/190 (11%) Query: 240 RISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQK--KKIIVFLS 297 + L P I++V E +T + +E +L L+ + Sbjct: 271 EVHLCGEPAAIDLVMELMYTTGEEVE--VRDYKRLTPISVLDHALESLDNLRPGDCIVCF 328 Query: 298 SCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFC--NAERGILICTDVAARGLDI 355 S N + + + L ++G + +F N IL+ TD GL++ Sbjct: 329 SKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQAKKFNDPNDPCKILVATDAIGMGLNL 388 Query: 356 PAVDWIIQFDP--------------PDDPRDYIHRVGRTAR-GTKGKGKSLMFLTPNELG 400 + II + P + GR R ++ K + + +L Sbjct: 389 S-IRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRFKEGEVTTMNHEDLS 447 Query: 401 FLRYLKASKV 410 L+ + V Sbjct: 448 LLKEILKRPV 457 >5GN1-A nrPDB Length = 366 Score = 49.2 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 60/153 (39%), Gaps = 4/153 (2%) Query: 277 FLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFC 336 L + ++++K+++F + +L+ +D L L G + R +F Sbjct: 190 LKKLLKTIIVDKQEKVLIFSLFTQVLDILEMVLSTLDYKFLRLDGSTQVNDRQLLIDKFY 249 Query: 337 NAE-RGILI-CTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFL 394 + I I T G+++ + +I FD +P D R R + K ++ L Sbjct: 250 EDKDIPIFILSTKAGGFGINLVCANNVIIFDQSFNPHDDRQAADRAHRVGQTKEVNITTL 309 Query: 395 TPNE--LGFLRYLKASKVPLNEYEFPENKIANV 425 + + L +K+ L+ Y + K +V Sbjct: 310 ITKDSIEEKIHQLAKNKLALDSYISEDKKSQDV 342 >6DCR-A nrPDB Length = 694 Score = 47.7 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 47/260 (18%), Positives = 85/260 (32%), Gaps = 51/260 (19%) Query: 69 QARTIPPLLAGRDV----LGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTR 124 QA + + + D L A TGSGKT + + +E + + G +V+ P Sbjct: 165 QATAVGAIHSAADTFSAWLLAGVTGSGKTEVY-LSVLENVLA------QGKQALVMVPEI 217 Query: 125 ELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVN----MLIATPGRLLDHLQ 180 L Q E + ++ G N + +K N ++I T + Sbjct: 218 GLTPQT---IARFRERFNAPVEVLHSGLNDSERLSAWLKAKNGEAAIVIGT--------R 266 Query: 181 NTKGFVFKNLKALIIDEADRIL---EIGFEDEMRQIIKILPNEDRQ-SMLFSATQT---- 232 + FKNL ++IDE + G+ R + + ++ +L SAT Sbjct: 267 SALFTPFKNLGVIVIDEEHDSSYKQQEGWRYHARDLAVYRAHSEQIPIILGSATPALETL 326 Query: 233 -------TKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLK 285 ++ L R + P +V+ GL + R Sbjct: 327 CNVQQKKYRLLRLTRRAGNARPAIQHVLDLKGQKVQAGLAPALIT-----RMRQHLQA-- 379 Query: 286 RNQKKKIIVFLSSCNSVKYY 305 ++I+FL+ Sbjct: 380 ---DNQVILFLNRRGFAPAL 396 Score = 41.5 bits (96), Expect = 9e-04, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 36/109 (33%), Gaps = 18/109 (16%) Query: 309 LNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDP-- 366 ++ ID G +QQ E ILI T + A+G P V + D Sbjct: 469 ISRIDRDTTSRKGALEQQ-----LAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDG 523 Query: 367 ----------PDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYL 405 + Y GR R K +G+ ++ E L+ L Sbjct: 524 ALFSADFRSAERFAQLYTQVAGRAGRAGK-QGEVVLQTHHPEHPLLQTL 571 Score = 30.7 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 25/60 (41%), Gaps = 1/60 (1%) Query: 288 QKKKIIVFLSSC-NSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICT 346 Q K+ +V + + + A + PV LH +R + + + N E I+I T Sbjct: 206 QGKQALVMVPEIGLTPQTIARFRERFNAPVEVLHSGLNDSERLSAWLKAKNGEAAIVIGT 265 >4UAQ-A nrPDB Length = 778 Score = 47.3 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 47/145 (32%), Gaps = 18/145 (12%) Query: 287 NQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICT 346 + + ++V + E L +P + L+ K ++ + + T Sbjct: 440 QRGQPVLVGTRDVAESEELHERLVRRGVPAVVLNAKNDAEEARVIAEAGKYGA--VTVST 497 Query: 347 DVAARGLDI----------PAVDWIIQFDPPDDPRDYIHRV-----GRTARGTKGKGKSL 391 +A RG DI V + R + R+ GR R G S+ Sbjct: 498 QMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQG-DPGSSV 556 Query: 392 MFLTPNELGFLRYLKASKVPLNEYE 416 F + + L +K+P+ E Sbjct: 557 FFSSWEDDVVAANLDHNKLPMATDE 581 >4ERN-A nrPDB Length = 289 Score = 46.5 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 45/121 (37%), Gaps = 7/121 (5%) Query: 268 YVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQK 327 Y + + R + KIIVF + ++K YA LN ++G Q + Sbjct: 41 YTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKP-----YIYGPTSQGE 95 Query: 328 RTNTFFEFC-NAERGILICTDVAARGLDIPAVDWIIQFDP-PDDPRDYIHRVGRTARGTK 385 R F N + + + V D+P + +IQ R R+GR R K Sbjct: 96 RMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKK 155 Query: 386 G 386 G Sbjct: 156 G 156 >5K9T-A nrPDB Length = 578 Score = 46.5 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 35/127 (27%), Positives = 53/127 (41%), Gaps = 15/127 (11%) Query: 82 VLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFH 141 + +TG GKTL +PA L++L G G+ V+T LA + R L EF Sbjct: 86 CIAEMRTGEGKTLTATLPA--YLNAL-----TGKGVHVVTVNDYLAQRDAENNRPLFEFL 138 Query: 142 SQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRL-LDHLQNTKGFVF-----KNLKALII 195 T GI + G + E ++ T D+L++ F + L ++ Sbjct: 139 GLTVGINLPGMPAPAKREA--YAADITYGTNNEYGFDYLRDNMAFSPAARVQRKLHYALV 196 Query: 196 DEADRIL 202 DE D IL Sbjct: 197 DEVDSIL 203 >2Z83-A nrPDB Length = 459 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 64/393 (16%), Positives = 117/393 (29%), Gaps = 87/393 (22%) Query: 64 TMTSVQA--RTIPPLLAGRDVLGA-AKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 +MT Q R P +L R + GSGKT ++P I +K + V+ Sbjct: 3 SMTGGQQMGRGSPNMLRKRQMTVLDLHPGSGKTRK-ILPQI-----IKDAIQQRLRTAVL 56 Query: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMK---GVNML-IATPGRLL 176 PTR VA E+ E G R + + + G ++ + L Sbjct: 57 APTR-------VVAAEMAEALR--------GLPVRYQTSAVQREHQGNEIVDVMCHATLT 101 Query: 177 DHLQNTKGFVFKNLKALIIDEAD-----RILEIGFEDEMRQIIKILPNEDRQSMLFSATQ 231 L + N ++DEA I G+ I + + ++ +AT Sbjct: 102 HRLMSPNRV--PNYNLFVMDEAHFTDPASIAARGY------IATKVELGEAAAIFMTATP 153 Query: 232 TTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKK 291 + + L + +S + + + K Sbjct: 154 PGTTDPFPDSNAPIHDLQDEIPDRAWSSGYEWITEY---------------------AGK 192 Query: 292 IIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAAR 351 + F++S A L V+ + ++ + + N + +I TD++ Sbjct: 193 TVWFVASVKMGNEIAMCLQRAGKKVI----QLNRKSYDTEYPKCKNGDWDFVITTDISEM 248 Query: 352 GLDIPAVDWI-----------------IQFDPPD--DPRDYIHRVGRTARGTKGKGKSLM 392 G + A I + P R GR R G Sbjct: 249 GANFGASRVIDCRKSVKPTILEEGEGRVILGNPSPITSASAAQRRGRVGRNPNQVGDEYH 308 Query: 393 FL--TPNELGFLRYLKASKVPLNEYEFPENKIA 423 + T + L + +K+ L+ P +A Sbjct: 309 YGGATSEDDSNLAHWTEAKIMLDNIHMPNGLVA 341 >2FSI-A nrPDB Length = 853 Score = 45.8 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 35/127 (27%), Positives = 53/127 (41%), Gaps = 15/127 (11%) Query: 82 VLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFH 141 + +TG GKTL +PA L++L G G+ V+T LA + R L EF Sbjct: 90 CIAEMRTGEGKTLTATLPA--YLNAL-----TGKGVHVVTVNDYLAQRDAENNRPLFEFL 142 Query: 142 SQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRL-LDHLQNTKGFVF-----KNLKALII 195 T GI + G + E ++ T D+L++ F + L ++ Sbjct: 143 GLTVGINLPGMPAPAKREA--YAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALV 200 Query: 196 DEADRIL 202 DE D IL Sbjct: 201 DEVDSIL 207 >3DIN-A nrPDB Length = 871 Score = 45.0 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 25/140 (17%), Positives = 54/140 (38%), Gaps = 13/140 (9%) Query: 269 VVCDSDKRFLLLFSFLKR--NQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQ 326 V +++ + +++ + + ++V +S + + +L +P L+ K ++ Sbjct: 452 VFRTQKEKYEKIVEEIEKRYKKGQPVLVGTTSIEKSELLSSMLKKKGIPHQVLNAKYHEK 511 Query: 327 KRTNTFFEFCNAERGILICTDVAARGLDI---PAVDWIIQFDPPDDPRDYIHRV-----G 378 + + I T++A RG DI P V + R R+ G Sbjct: 512 EAEIVAKAGQKGM--VTIATNMAGRGTDIKLGPGVAELGGLCIIGTERHESRRIDNQLRG 569 Query: 379 RTARGTKGKGKSLMFLTPNE 398 R R G+S+ FL+ + Sbjct: 570 RAGRQG-DPGESIFFLSLED 588 Score = 28.8 bits (63), Expect = 5.9, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 11/18 (61%) Query: 83 LGAAKTGSGKTLAFLIPA 100 + KTG GKTLA +P Sbjct: 92 VAEMKTGEGKTLAATMPI 109 >4NL8-A nrPDB Length = 747 Score = 44.2 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 45/116 (38%), Gaps = 22/116 (18%) Query: 88 TGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGI 147 TGSGKT + + +E + + G +V+ P L Q + + + Sbjct: 241 TGSGKTEVY-LSVLENVLA------QGRQALVMVPEIGLTPQT---IARFRQRFNAPVEV 290 Query: 148 VIGGANRRQEAEKLMKGVN----MLIATPGRLLDHLQNTKGFVFKNLKALIIDEAD 199 + G N + +K N ++I T +++ FK+L ++IDE Sbjct: 291 LHSGLNDSERLSAWLKAKNGEAAIVIGT--------RSSLFTPFKDLGVIVIDEEH 338 Score = 39.6 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 27/89 (30%), Gaps = 13/89 (14%) Query: 329 TNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDP------------PDDPRDYIHR 376 ILI T + A+G P V + D + Y Sbjct: 537 EEHLAAVHRGGARILIGTQMLAKGHHFPDVTLVSLLDVDGALFSADFRSAERFAQLYTQV 596 Query: 377 VGRTARGTKGKGKSLMFLTPNELGFLRYL 405 GR R K +G+ ++ E L+ L Sbjct: 597 SGRAGRAGK-QGEVILQTHHPEHPLLQTL 624 Score = 30.7 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 17/42 (40%) Query: 305 YAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICT 346 A + PV LH +R + + + N E I+I T Sbjct: 277 IARFRQRFNAPVEVLHSGLNDSERLSAWLKAKNGEAAIVIGT 318 >2BMF-A nrPDB Length = 451 Score = 44.2 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 57/375 (15%), Positives = 113/375 (30%), Gaps = 106/375 (28%) Query: 89 GSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIV 148 G+GKT + +PAI + G +++ PTR +A Sbjct: 29 GAGKTKRY-LPAIVR-----EAIKRGLRTLILAPTRVVA--------------------- 61 Query: 149 IGGANRRQEAEKLMKGVNMLIATP-------GR-LLDHLQNTKG-------FVFKNLKAL 193 E E+ ++G+ + TP GR ++D + + N + Sbjct: 62 -------AEMEEALRGLPIRYQTPAIRAEHTGREIVDLMCHATFTMRLLSPIRVPNYNLI 114 Query: 194 IIDEAD-----RILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPL 248 I+DEA I G+ I + + + +AT + + + Sbjct: 115 IMDEAHFTDPASIAARGY------ISTRVEMGEAAGIFMTATPPGSRDPFPQSNAPIMDE 168 Query: 249 FINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAEL 308 + + NS + + K K + F+ S + A Sbjct: 169 EREIPERSWNSGHEWVTDF---------------------KGKTVWFVPSIKAGNDIAAC 207 Query: 309 LNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDW-------- 360 L V+ + ++ + + + + ++ TD++ G + A Sbjct: 208 LRKNGKKVI----QLSRKTFDSEYIKTRTNDWDFVVTTDISEMGANFKAERVIDPRRCMK 263 Query: 361 -IIQFD----------PPDDPRDYIHRVGRTARGTKGKGKSLMFLTP--NELGFLRYLKA 407 +I D P R GR R K + +++ + K Sbjct: 264 PVILTDGEERVILAGPMPVTHSSAAQRRGRVGRNPKNENDQYIYMGEPLENDEDCAHWKE 323 Query: 408 SKVPLNEYEFPENKI 422 +K+ L+ PE I Sbjct: 324 AKMLLDNINTPEGII 338 >3H1T-A nrPDB Length = 590 Score = 43.8 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 64/366 (17%), Positives = 107/366 (29%), Gaps = 66/366 (18%) Query: 71 RTIPPLLAG--RDVLGAAKTGSGKTL-AFLIPAIELLHSLKFKPRN-GTGIIVITPTREL 126 R + +L G R ++ A TG+GKT+ AF I I+ + L Sbjct: 189 RAVQSVLQGKKRSLITMA-TGTGKTVVAFQISWKLWSARWNRTGDYRKPRILFLADRNVL 247 Query: 127 ALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFV 186 + + GG + + + IA+ R K F Sbjct: 248 VDDPKD---KTFTPFGDARHKIEGGKVVKSRE--IYFAIYQSIASDER---RPGLYKEFP 299 Query: 187 FKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSAT-QTTKVEDLARISLRP 245 +IIDE R R+I++ Q + +AT D R P Sbjct: 300 QDFFDLIIIDECHRGSARD-NSNWREILEYF-EPAFQIGM-TATPLREDNRDTYRYFGNP 356 Query: 246 GPLF----------------INVVPETDN---------------STADGLEQ-------G 267 + V+ E D DG Q Sbjct: 357 IYTYSLRQGIDDGFLAPYRVHRVISEVDAAGWRPSKGDVDRFGREIPDGEYQTKDFERVI 416 Query: 268 YVVCDSDKRFLLLFSFLKR-NQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELH----GK 322 + +D L F+KR ++ K IVF LN ++ + H + Sbjct: 417 ALKARTDAFAKHLTDFMKRTDRFAKTIVFCVDQEHADEMRRALNNLNSDLSRKHPDYVAR 476 Query: 323 QKQQK------RTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHR 376 ++ + F E + IL + + G+D P ++ + ++ Sbjct: 477 VTSEEGKIGKGHLSRFQELETSTPVILTTSQLLTTGVDAPTCKNVVLARVVNSMSEFKQI 536 Query: 377 VGRTAR 382 VGR R Sbjct: 537 VGRGTR 542 >1Z6A-A nrPDB Length = 500 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 49/111 (44%), Gaps = 11/111 (9%) Query: 281 FSFLKR--NQKKKIIVFLSSCNSVKYYAELL-NYIDLPVLELHGKQKQQKRTNTFFEFCN 337 ++ ++ KI +F + K ++ ++ V L+G+ +++R + +F N Sbjct: 331 MEIIEEALDEGDKIAIFTQFVDMGKIIRNIIEKELNTEVPFLYGELSKKERDDIISKFQN 390 Query: 338 AERG--ILICTDVAARGLDIPAVDWIIQFD------PPDDPRDYIHRVGRT 380 I++ G+++ + + +I FD D D ++R+G+T Sbjct: 391 NPSVKFIVLSVKAGGFGINLTSANRVIHFDRWWNPAVEDQATDRVYRIGQT 441 >2WV9-A nrPDB Length = 673 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 53/362 (14%), Positives = 106/362 (29%), Gaps = 78/362 (21%) Query: 89 GSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVAREL-MEFHSQTFGI 147 G+GKT ++P I +K + V+ PTR +A ++ R L + + + Sbjct: 251 GAGKTRR-ILPQI-----IKDAIQKRLRTAVLAPTRVVAAEMAEALRGLPVRYLTPAVQR 304 Query: 148 VIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEAD-----RIL 202 G + + T RL+ N ++DEA I Sbjct: 305 EHSGNEIVDVM------CHATL-TH-RLM------SPLRVPNYNLFVMDEAHFTDPASIA 350 Query: 203 EIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTAD 262 G+ I + + ++ +AT + + + + +S + Sbjct: 351 ARGY------IATRVEAGEAAAIFMTATPPGTSDPFPDTNSPVHDVSSEIPDRAWSSGFE 404 Query: 263 GLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGK 322 + K + F++S A+ L V+ + Sbjct: 405 WITDY---------------------AGKTVWFVASVKMSNEIAQCLQRAGKRVI----Q 439 Query: 323 QKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWI-----------------IQFD 365 ++ + + N + +I TD++ G + A I + Sbjct: 440 LNRKSYDTEYPKCKNGDWDFVITTDISEMGANFGASRVIDCRKSVKPTILDEGEGRVILS 499 Query: 366 PPD--DPRDYIHRVGRTARGTKGKGKSLMF--LTPNELGFLRYLKASKVPLNEYEFPENK 421 P R GR R G + T + L + +K+ L+ P Sbjct: 500 VPSAITSASAAQRRGRVGRNPSQIGDEYHYGGGTSEDDTMLAHWTEAKILLDNIHLPNGL 559 Query: 422 IA 423 +A Sbjct: 560 VA 561 >2V8O-A nrPDB Length = 444 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 53/362 (14%), Positives = 106/362 (29%), Gaps = 78/362 (21%) Query: 89 GSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVAREL-MEFHSQTFGI 147 G+GKT ++P I +K + V+ PTR +A ++ R L + + + Sbjct: 22 GAGKTRR-ILPQI-----IKDAIQKRLRTAVLAPTRVVAAEMAEALRGLPVRYLTPAVQR 75 Query: 148 VIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEAD-----RIL 202 G + + T RL+ N ++DEA I Sbjct: 76 EHSGNEIVDVM------CHATL-TH-RLM------SPLRVPNYNLFVMDEAHFTDPASIA 121 Query: 203 EIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTAD 262 G+ I + + ++ +AT + + + + +S + Sbjct: 122 ARGY------IATRVEAGEAAAIFMTATPPGTSDPFPDTNSPVHDVSSEIPDRAWSSGFE 175 Query: 263 GLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGK 322 + K + F++S A+ L V+ + Sbjct: 176 WITDY---------------------AGKTVWFVASVKMSNEIAQCLQRAGKRVI----Q 210 Query: 323 QKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWI-----------------IQFD 365 ++ + + N + +I TD++ G + A I + Sbjct: 211 LNRKSYDTEYPKCKNGDWDFVITTDISEMGANFGASRVIDCRKSVKPTILDEGEGRVILS 270 Query: 366 PPD--DPRDYIHRVGRTARGTKGKGKSLMF--LTPNELGFLRYLKASKVPLNEYEFPENK 421 P R GR R G + T + L + +K+ L+ P Sbjct: 271 VPSAITSASAAQRRGRVGRNPSQIGDEYHYGGGTSEDDTMLAHWTEAKILLDNIHLPNGL 330 Query: 422 IA 423 +A Sbjct: 331 VA 332 >1NL3-A nrPDB Length = 922 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 29/126 (23%), Positives = 52/126 (41%), Gaps = 15/126 (11%) Query: 83 LGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS 142 + KTG GKTL ++PA L++L G G+ ++T LA + + F Sbjct: 128 VAEMKTGEGKTLTCVLPA--YLNAL-----AGNGVHIVTVNDYLAKRDSEWMGRVHRFLG 180 Query: 143 QTFGIVIGGANRRQEAEKLMKGVNMLIATPGRL-LDHLQNTKGFVFKNL-----KALIID 196 G+++ A + ++ ++ T D+L++ +L I+D Sbjct: 181 LQVGVIL--ATMTPDERRVAYNADITYGTNNEFGFDYLRDNMAHSLDDLVQRGHHYAIVD 238 Query: 197 EADRIL 202 E D IL Sbjct: 239 EVDSIL 244 Score = 33.0 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 27/156 (17%), Positives = 55/156 (35%), Gaps = 13/156 (8%) Query: 229 ATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKR-N 287 A T + A L + +P + + K ++ +R Sbjct: 399 AGMTGTAQTEAAELHEIYKLGVVSIPTNMPMIREDQSDLIYKTEEAKYIAVVDDVAERYA 458 Query: 288 QKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTD 347 + + +++ +S +Y + +P L+ K +Q+ T G+ + T+ Sbjct: 459 KGQPVLIGTTSVERSEYLSRQFTKRRIPHNVLNAKYHEQEATIIAVAGRRG--GVTVATN 516 Query: 348 VAARGLDI---PAVDWIIQ-------FDPPDDPRDY 373 +A RG DI VD++ DP + P +Y Sbjct: 517 MAGRGTDIVLGGNVDFLTDQRLRERGLDPVETPEEY 552 >1Z5Z-A nrPDB Length = 271 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 49/111 (44%), Gaps = 11/111 (9%) Query: 281 FSFLKR--NQKKKIIVFLSSCNSVKYYAELL-NYIDLPVLELHGKQKQQKRTNTFFEFCN 337 ++ ++ KI +F + K ++ ++ V L+G+ +++R + +F N Sbjct: 102 MEIIEEALDEGDKIAIFTQFVDMGKIIRNIIEKELNTEVPFLYGELSKKERDDIISKFQN 161 Query: 338 AERG--ILICTDVAARGLDIPAVDWIIQFD------PPDDPRDYIHRVGRT 380 I++ G+++ + + +I FD D D ++R+G+T Sbjct: 162 NPSVKFIVLSVKAGGFGINLTSANRVIHFDRWWNPAVEDQATDRVYRIGQT 212 >2JLW-A nrPDB Length = 451 Score = 42.3 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 50/318 (15%), Positives = 100/318 (31%), Gaps = 74/318 (23%) Query: 89 GSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIV 148 G+GKT ++P+I +LK + R +++ PTR +A ++ R L V Sbjct: 29 GAGKTKR-ILPSIVR-EALKRRLR----TLILAPTRVVAAEMEEALRGL--PIRYQTPAV 80 Query: 149 IGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFED 208 R+ + + + T RLL N +++DEA F D Sbjct: 81 KSDHTGREIVDLM---CHATFTT--RLL------SSTRVPNYNLIVMDEAH------FTD 123 Query: 209 EM-----RQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADG 263 I + + ++ +AT ++ + + + + + N+ D Sbjct: 124 PCSVAARGYISTRVEMGEAAAIFMTATPPGSIDPFPQSNSPIEDIEREIPERSWNTGFDW 183 Query: 264 LEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQ 323 + K + F+ S + A L V+ + Sbjct: 184 ITDYQ---------------------GKTVWFVPSIKAGNDIANCLRKSGKRVI----QL 218 Query: 324 KQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDW---------IIQFDPPD------ 368 ++ + + + ++ TD++ G + A +I D P+ Sbjct: 219 SRKTFDTEYPKTKLTDWDFVVTTDISEMGANFRAGRVIDPRRCLKPVILTDGPERVILAG 278 Query: 369 ----DPRDYIHRVGRTAR 382 P R GR R Sbjct: 279 PIPVTPASAAQRRGRIGR 296 >2WZQ-A nrPDB Length = 619 Score = 41.9 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 50/318 (15%), Positives = 99/318 (31%), Gaps = 74/318 (23%) Query: 89 GSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIV 148 G+GKT ++P+I +LK + R +++ PTR +A ++ R L V Sbjct: 197 GAGKTKR-ILPSIVR-EALKRRLR----TLILAPTRVVAAEMEEALRGL--PIRYQTPAV 248 Query: 149 IGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFED 208 R+ + + + T RLL N +++DEA F D Sbjct: 249 KSDHTGREIVDLM---CHATFTT--RLL------SSTRVPNYNLIVMDEAH------FTD 291 Query: 209 EM-----RQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADG 263 I + + ++ +AT + + + + + + N+ D Sbjct: 292 PCSVAARGYISTRVEMGEAAAIFMTATPPGSTDPFPQSNSPIEDIEREIPERSWNTGFDW 351 Query: 264 LEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQ 323 + K + F+ S + A L V+ + Sbjct: 352 ITDYQ---------------------GKTVWFVPSIKAGNDIANCLRKSGKRVI----QL 386 Query: 324 KQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDW---------IIQFDPPD------ 368 ++ + + + ++ TD++ G + A +I D P+ Sbjct: 387 SRKTFDTEYPKTKLTDWDFVVTTDISEMGANFRAGRVIDPRRCLKPVILTDGPERVILAG 446 Query: 369 ----DPRDYIHRVGRTAR 382 P R GR R Sbjct: 447 PIPVTPASAAQRRGRIGR 464 >2V6J-A nrPDB Length = 431 Score = 41.1 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 49/325 (15%), Positives = 94/325 (28%), Gaps = 63/325 (19%) Query: 89 GSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVAR-ELMEFHSQTFGI 147 G+GKT ++P + + +++ PTR +A + + R E + + + Sbjct: 12 GAGKTRR-VLPQLVR-----EAVKKRLRTVILAPTRVVASETYEALRGEPIRYMTPAVQ- 64 Query: 148 VIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFE 207 + R E + + ++ +G N I+DEA L+ Sbjct: 65 -----SERTGNEIVDFMCHSTFT--------MKLLQGVRVPNYNLYIMDEAH-FLDPASV 110 Query: 208 DEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQG 267 I + D ++ +AT E P ++ E G Sbjct: 111 AARGYIETRVSMGDAGAIFMTATPPGTTEAF-------PPSNSPIIDEETRIPDKAWNSG 163 Query: 268 YVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQK 327 Y + + F+ S L VL L+ K + + Sbjct: 164 YEWITEFD--------------GRTVWFVHSIKQGAEIGTCLQKAGKKVLYLNRKTFESE 209 Query: 328 RTNTFFEFCNAERGILICTDVAARGLDIPAVDWI--------------IQFDPPD--DPR 371 + + + + +I TD++ G + A I + P P Sbjct: 210 ----YPKCKSEKWDFVITTDISEMGANFKADRVIDPRKTIKPILLDGRVSMQGPIAITPA 265 Query: 372 DYIHRVGRTARGTKGKGKSLMFLTP 396 R GR R + G + Sbjct: 266 SAAQRRGRIGRNPEKLGDIYAYSGN 290 >5EUL-A nrPDB Length = 836 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 33/126 (26%), Positives = 57/126 (45%), Gaps = 15/126 (11%) Query: 83 LGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS 142 + KTG GKTL +P L++L G G+ V+T LA + ++ EF Sbjct: 97 IAEMKTGEGKTLTSTLPV--YLNAL-----TGKGVHVVTVNEYLASRDAEQMGKIFEFLG 149 Query: 143 QTFGIVIGGANRRQEAEKLMKGVNMLIATPGRL-LDHLQNT-----KGFVFKNLKALIID 196 T G+ + ++ ++ E ++ +T L D+L++ + V + L +ID Sbjct: 150 LTVGLNLNSMSKDEKREA--YAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVID 207 Query: 197 EADRIL 202 E D IL Sbjct: 208 EVDSIL 213 Score = 39.6 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 30/186 (16%), Positives = 63/186 (33%), Gaps = 14/186 (7%) Query: 227 FSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKR 286 + T T+ E+ I + + D + Y + + + + Sbjct: 370 MTGTAKTEEEEFRNIYNMQ---VVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRY 426 Query: 287 NQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICT 346 + ++V + + + ++LL +P L+ K +R E + + I T Sbjct: 427 MTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAK--NHEREAQIIEEAGQKGAVTIAT 484 Query: 347 DVAARGLDI---PAVDWIIQFDPPDDPRDYIHRV-----GRTARGTKGKGKSLMFLTPNE 398 ++A RG DI V + R R+ GR+ R G + +L+ + Sbjct: 485 NMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQG-DPGITQFYLSMED 543 Query: 399 LGFLRY 404 R+ Sbjct: 544 ELMRRF 549 >1TF2-A nrPDB Length = 844 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 33/126 (26%), Positives = 57/126 (45%), Gaps = 15/126 (11%) Query: 83 LGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS 142 + KTG GKTL +P L++L G G+ V+T LA + ++ EF Sbjct: 100 IAEMKTGEGKTLTSTLPV--YLNAL-----TGKGVHVVTVNEYLASRDAEQMGKIFEFLG 152 Query: 143 QTFGIVIGGANRRQEAEKLMKGVNMLIATPGRL-LDHLQNT-----KGFVFKNLKALIID 196 T G+ + ++ ++ E ++ +T L D+L++ + V + L +ID Sbjct: 153 LTVGLNLNSMSKDEKREA--YAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVID 210 Query: 197 EADRIL 202 E D IL Sbjct: 211 EVDSIL 216 Score = 39.2 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 30/186 (16%), Positives = 63/186 (33%), Gaps = 14/186 (7%) Query: 227 FSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKR 286 + T T+ E+ I + + D + Y + + + + Sbjct: 373 MTGTAKTEEEEFRNIYNMQ---VVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRY 429 Query: 287 NQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICT 346 + ++V + + + ++LL +P L+ K +R E + + I T Sbjct: 430 MTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAK--NHEREAQIIEEAGQKGAVTIAT 487 Query: 347 DVAARGLDI---PAVDWIIQFDPPDDPRDYIHRV-----GRTARGTKGKGKSLMFLTPNE 398 ++A RG DI V + R R+ GR+ R G + +L+ + Sbjct: 488 NMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQG-DPGITQFYLSMED 546 Query: 399 LGFLRY 404 R+ Sbjct: 547 ELMRRF 552 >1Z3I-X nrPDB Length = 644 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 27/180 (15%), Positives = 59/180 (32%), Gaps = 8/180 (4%) Query: 277 FLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFC 336 + + + K+++ + ++ + +L + L G +KR F Sbjct: 404 LDYILAMTRTTTSDKVVLVSNYTQTLDLFEKLCRNRRYLYVRLDGTMSIKKRAKIVERFN 463 Query: 337 NAERG---ILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMF 393 N ++ + GL++ + ++ FDP +P + + R R + K + Sbjct: 464 NPSSPEFIFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYR 523 Query: 394 LTPN---ELGFLRYLKASKVPLNEYEFPENKIA--NVQSQLEKLIKSNYYLHQTAKDGYR 448 L E L+ K + E + +L +L N D +R Sbjct: 524 LLSTGTIEEKILQRQAHKKALSSCVVDEEQDVERHFSLGELRELFSLNEKTLSDTHDRFR 583 >1RIF-A nrPDB Length = 282 Score = 38.8 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 46/131 (35%), Gaps = 13/131 (9%) Query: 69 QARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELAL 128 Q + L R + T +G++L I+ L + + I++I PT L Sbjct: 118 QKDAVFEGLVNRRRILNLPTSAGRSL------IQALLARYYLENYEGKILIIVPTTALTT 171 Query: 129 QIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFK 188 Q+ + F + GGA++ +K +++ T ++ F Sbjct: 172 QMADDFVDYRLFSHAMIKKIGGGASKD---DKYKNDAPVVVGTWQTVV----KQPKEWFS 224 Query: 189 NLKALIIDEAD 199 ++ DE Sbjct: 225 QFGMMMNDECH 235 >4QQW-A nrPDB Length = 964 Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 37/252 (14%), Positives = 76/252 (30%), Gaps = 63/252 (25%) Query: 191 KALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVED-LARISLRPG--- 246 K +++DEA + + + + Q+++ L D +L SAT + + L + L Sbjct: 466 KVVVVDEAHAV-DPYMQVLLEQLLRWLGTLDVPVVLLSATLHHSIANSLVKAYLEGARGR 524 Query: 247 ---------------PLFINVVPETDNSTAD-GLEQGYVVCDSDKRF--LLLFSFLKRNQ 288 P +++V T ++ + K L+ +K Sbjct: 525 RWNRSEPQPVSEVSYPGWLHVDARIGKVTRSSDVDPLPIATTPRKPLEVRLVDVPVKEGA 584 Query: 289 KKK-----------------IIVFLSSCNSV----KYYAELLNYIDLPV---LELHGKQK 324 + + ++ ++ + LH + Sbjct: 585 LNRSTVLAKELTPLVKQGGCAAIICTTVAEAQGVYDLLSQWFATLGEDAPDLYLLHSRFP 644 Query: 325 QQKRTNT----FFEF-CNAERG--------ILICTDVAARGLDIPAVDWIIQFDPPDDPR 371 ++RT F + +L+ T V + LD+ VD +I P Sbjct: 645 NRQRTEITATIVDLFGKEGAQSGRRPTRGAVLVATQVVEQSLDL-DVDLMISDLAPVSLL 703 Query: 372 DYIHRVGRTARG 383 + R GR R Sbjct: 704 --LQRAGRCWRH 713 >6FWS-A nrPDB Length = 716 Score = 37.7 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 14/71 (19%) Query: 65 MTSVQARTIPPLL------AGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGII 118 + Q + I + GR + A TG GKTL++LIP I + R + Sbjct: 27 PRAPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAI-------AREEQKTL 79 Query: 119 VITPTRELALQ 129 V++ T +ALQ Sbjct: 80 VVS-TANVALQ 89 >2FZ4-A nrPDB Length = 237 Score = 34.6 bits (78), Expect = 0.097, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 24/61 (39%), Gaps = 10/61 (16%) Query: 69 QARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELAL 128 Q + + L + TGSGKT + AI L T +++ PT LA Sbjct: 98 QEKALERWLVDKRGCIVLPTGSGKTHV-AMAAINELS---------TPTLIVVPTLALAE 147 Query: 129 Q 129 Q Sbjct: 148 Q 148 >2IPC-A nrPDB Length = 997 Score = 33.0 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 48/129 (37%), Gaps = 18/129 (13%) Query: 83 LGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHS 142 + KTG GKTL + L++L G G+ V+T LA + + Sbjct: 96 IAEMKTGEGKTLVATLAV--ALNAL-----TGKGVHVVTVNDYLARRDAEWMGPVYRGLG 148 Query: 143 QTFGIVIGGANRRQEAEKLMKGVNMLIATPGRL-LDHLQNTKGFVFKN--------LKAL 193 + G++ + + + + ++ T L D+L++ L Sbjct: 149 LSVGVIQHASTPAERRKAYL--ADVTYVTNSELGFDYLRDNMAISPDQLVLRHDHPLHYA 206 Query: 194 IIDEADRIL 202 IIDE D IL Sbjct: 207 IIDEVDSIL 215 >6EG3-A nrPDB Length = 621 Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats. Identities = 35/164 (21%), Positives = 60/164 (36%), Gaps = 20/164 (12%) Query: 69 QARTIPPLLAGRDV--LGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTREL 126 Q L ++ + A + G GKT I I L+ L R ++I P L Sbjct: 396 QGLEWMVSLYNNNLNGILADEMGLGKT----IQTIALITYLMEHKRLNGPYLIIVPLSTL 451 Query: 127 ALQIFGVARELMEFHSQTFGIVIGGAN--RRQEAEKLMKG-VNMLIATPGRLLDHLQNTK 183 E ++ I G RR +L G N+L+ T +++ K Sbjct: 452 ----SNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTT----YEYIIKDK 503 Query: 184 GFVFK-NLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSML 226 + K K +I+DE R+ ++ Q++ R+ +L Sbjct: 504 HILAKIRWKYMIVDEGHRMKN--HHCKLTQVLNTHYVAPRRILL 545 >1PEQ-A nrPDB Length = 714 Score = 32.7 bits (73), Expect = 0.44, Method: Composition-based stats. Identities = 35/228 (15%), Positives = 69/228 (30%), Gaps = 26/228 (11%) Query: 95 AFLIPAIELLH--------SLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFG 146 FL+ + + +L+ R G +++ RE I + + Sbjct: 178 CFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKM 237 Query: 147 IVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGF 206 + ++A + G + H + F + K DE RI + Sbjct: 238 L--------EDAFSYANQLGARQGA-GAVYLHAHHPDILRFLDTKRENADEKIRIKTLSL 288 Query: 207 EDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQ 266 + I L E+ Q LFS ++ R +P + + + Sbjct: 289 GVVIPDITFRLAKENAQMALFS---PYDIQ---RRYGKPFGDIAISERYDELIADPHVRK 342 Query: 267 GYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDL 314 Y+ ++ F L + I+F + N A +N +L Sbjct: 343 TYI--NARDFFQTLAEI-QFESGYPYIMFEDTVNRANPIAGRINMSNL 387 >2NQ2-C nrPDB Length = 253 Score = 32.3 bits (72), Expect = 0.52, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 33/81 (40%) Query: 188 KNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGP 247 K +++DE L++ +D + ++ L +++F+ Q +V +A +L Sbjct: 145 SECKLILLDEPTSALDLANQDIVLSLLIDLAQSQNMTVVFTTHQPNQVVAIANKTLLLNK 204 Query: 248 LFINVVPETDNSTADGLEQGY 268 + T++ L + Sbjct: 205 QNFKFGETRNILTSENLTALF 225 >6D00-1 nrPDB Length = 883 Score = 31.9 bits (71), Expect = 0.70, Method: Composition-based stats. Identities = 38/252 (15%), Positives = 72/252 (28%), Gaps = 60/252 (23%) Query: 68 VQARTIPPL----------LAGRD-----VLGAAKTGSGKTLAFLIPAIELLHSLKFKPR 112 Q I + L R+ L TG GKTL + L Sbjct: 574 GQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLC--------VKELAAFLF 625 Query: 113 NGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEA-EKLMKGVNMLIAT 171 N G IV E + + G + G + + E + + ++ Sbjct: 626 NDPGAIVRIDMSE-----YMEKHAVSRLVGAPPGYI--GHDEGGQLTEAVRRRPYTVV-- 676 Query: 172 PGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMR-QIIKILPN----------- 219 L D ++ NL I+D+ G + + II + N Sbjct: 677 ---LFDEMEKAH-KDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLGADLFELDEG 732 Query: 220 -----EDRQSMLFSA------TQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGY 268 + ++L +A ++++L + +V + L++ Sbjct: 733 DKVSQATKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQ 792 Query: 269 VVCDSDKRFLLL 280 + D D + L Sbjct: 793 ITLDVDDKAKDL 804 >1NLZ-A nrPDB Length = 330 Score = 31.5 bits (70), Expect = 0.89, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 40/118 (33%), Gaps = 24/118 (20%) Query: 58 EKMGFTTMTSVQARTIPPLLAG----RDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRN 113 E+ GF + + + I + G ++V+ TGSGKT ++ +E + Sbjct: 146 EEQGFYNLLDNKEQAISAIKDGIAIGKNVIVCGGTGSGKT-TYIKSIMEFI--------- 195 Query: 114 GTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQE--AEKLMKGVNMLI 169 P E + I + + H + GG + L + +I Sbjct: 196 --------PKEERIISIEDTEEIVFKHHKNYTQLFFGGNITSADCLKSCLRMRPDRII 245 >5B55-A nrPDB Length = 340 Score = 31.5 bits (70), Expect = 0.90, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 30/71 (42%), Gaps = 4/71 (5%) Query: 277 FLLLFSFLKRNQKKKI--IVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFE 334 F L ++N+ KK IV +S N+ ++ + + PV+ ++R + Sbjct: 55 FYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRS 114 Query: 335 FCNAERGILIC 345 F + IL+ Sbjct: 115 F--GAKIILVS 123 >5H8W-A nrPDB Length = 597 Score = 31.1 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 21/59 (35%), Gaps = 6/59 (10%) Query: 86 AKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQT 144 + TGSGKT + L +L++ ++ + T Q+ R L Sbjct: 11 SPTGSGKT------IMALKSALQYSSERKLKVLYLVRTNSQEEQVIKELRSLSSTMKIR 63 >5O6D-A nrPDB Length = 545 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 30/158 (18%), Positives = 55/158 (34%), Gaps = 29/158 (18%) Query: 66 TSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRE 125 + Q I G ++ G+GK+ + K G + +T + Sbjct: 3 SKEQESIIKLAENGHNIFYTGSAGTGKS------ILLREMIKVLKGIYGRENVAVTASTG 56 Query: 126 LALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGF 185 LA T G + +A+KL K V R HL+ Sbjct: 57 LA---------ACNIGGITIHSFAGIGLGKGDADKLYKKVR-------RSRKHLRRW--- 97 Query: 186 VFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQ 223 +N+ AL++DE +L+ D++ I + + ++ Q Sbjct: 98 --ENIGALVVDEI-SMLDAELLDKLDFIARKI-RKNHQ 131 >3M6A-A nrPDB Length = 543 Score = 30.4 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 8/40 (20%), Positives = 17/40 (42%), Gaps = 5/40 (12%) Query: 170 ATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDE 209 A PGR++ ++ ++DE D++ F + Sbjct: 160 AMPGRIIQGMKKAGKLNP----VFLLDEIDKMSS-DFRGD 194 >3J1C-A nrPDB Length = 563 Score = 30.4 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 39/300 (13%), Positives = 100/300 (33%), Gaps = 35/300 (11%) Query: 32 APEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSG 91 P+G ++ F ++ ++ +++M A+ + +D ++ G G Sbjct: 42 GPKGLDKMLIDSFGDVTITNDGATIVKEMEIQHPA---AKLLVEAAKAQD----SEVGDG 94 Query: 92 KTLAFLIPAIELLHSLKFKPRNGTGIIVI-------TPTRELALQ------IFGVARELM 138 T A ++ + L + +N I+I + EL Q + + Sbjct: 95 TTSAVVLAGLFLEKAESLVDQNIHPTIIIEGFKKAFNKSLELLPQLATKVDVSDLNSATA 154 Query: 139 EFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKG-FVFKNLKALIIDE 197 + + E E+L K ++++I + + L + +K Sbjct: 155 RDALKKIVYTTMSSKFMAEGEELNKIMDIVIDAVTTVAEPLPDGGYNVSLDLIKI----- 209 Query: 198 ADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETD 257 D+ + G ++ + I I+ +++ + A +VE A+I++ L + + Sbjct: 210 -DK-KKGGTIEDSQLIRGIVLDKE----VVHAGMPRRVEK-AKIAVLDASLEVEKPEISA 262 Query: 258 NSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVL 317 + +Q D + ++ L + + V + L + + Sbjct: 263 KISITSPDQIKAFLDEEAKY--LKDMVDKLASIGANVVICQKGIDDIAQHFLAKRGILAV 320 >3EAG-A nrPDB Length = 326 Score = 30.0 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 34/109 (31%), Gaps = 23/109 (21%) Query: 305 YAELLNYIDLPVLELHGKQ-----KQQKRT--NTFFEFC-----NAERGILICTDVAARG 352 A + V K Q + + + F + + + +VA RG Sbjct: 20 LAAIAKEAGFEVSGCDAKMYPPMSTQLEALGIDVYEGFDAAQLDEFKADVYVIGNVAKRG 79 Query: 353 LDIPAVDWIIQFDPPD------DPRDYIHR---VGRTARGTKGKGKSLM 392 +D+ V+ I+ P + +H +G K S++ Sbjct: 80 MDV--VEAILNLGLPYISGPQWLSENVLHHHWVLGVAGTHGKTTTASML 126 >2IUS-A nrPDB Length = 512 Score = 30.0 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 26/141 (18%), Positives = 55/141 (39%), Gaps = 9/141 (6%) Query: 130 IFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKN 189 + + R + + G + EA+++M+ + PG D + + K Sbjct: 240 VNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPG---DSMDAQHPVLKKE 296 Query: 190 LKALII-DE-ADRILEIGFEDEMRQIIKILPNEDR--QSMLFSATQTTKVEDLARISLRP 245 +++ DE AD ++ +G ++ ++I L + R L ATQ V+ + + Sbjct: 297 PYIVVLVDEFADLMMTVG--KKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKAN 354 Query: 246 GPLFINVVPETDNSTADGLEQ 266 P I + + L+Q Sbjct: 355 IPTRIAFTVSSKIDSRTILDQ 375 >1F4U-A nrPDB Length = 368 Score = 29.6 bits (65), Expect = 3.8, Method: Composition-based stats. Identities = 14/110 (12%), Positives = 35/110 (31%), Gaps = 14/110 (12%) Query: 196 DEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPE 255 DE + F + Q ++ E +S+L S + +D+ + P P+ + Sbjct: 77 DELRSMSADIFSPQKLQTLETFIRETTRSLLDS--IDPREDDIVKKLAVPLPIIVIS--- 131 Query: 256 TDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYY 305 + + + ++F + K +F ++ Sbjct: 132 ---------KILGLPIEDKEKFKEWSDLVAFRLGKPGEIFELGKKYLELI 172 >4ZIR-B nrPDB Length = 268 Score = 29.2 bits (64), Expect = 4.7, Method: Composition-based stats. Identities = 36/169 (21%), Positives = 70/169 (41%), Gaps = 27/169 (15%) Query: 79 GRDVLGAAKTGSGKT-----LAFLIPA-----IELLHSLKFKPRNGTGIIVITPTRELAL 128 G+ + K GSGKT LA L+ A ++ + F R G + P+ Sbjct: 37 GKIYVVVGKNGSGKTTLLKILAGLLAAAGEIFLDGSPADPFLLRKNVGYVFQNPSS---- 92 Query: 129 QIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKG---- 184 QI G E F + I G + + +++ K + ++ + D L + G Sbjct: 93 QIIGATVE----EDVAFSLEIMGLDESEMRKRIKKVLELVGLSGLAAADPLNLSGGQKQR 148 Query: 185 -----FVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFS 228 + ++ + L +DE +L+ + E+ Q+++ L NE + +L + Sbjct: 149 LAIASMLARDTRFLALDEPVSMLDPPSQREIFQVLESLKNEGKGIILVT 197 >1CTU-A nrPDB Length = 294 Score = 28.8 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 4/49 (8%) Query: 155 RQEAEKLMKGVNMLIATPGR----LLDHLQNTKGFVFKNLKALIIDEAD 199 RQ +L G+++ I PGR L D+L + G +K L++DE D Sbjct: 133 RQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQD 181 >1YID-B nrPDB Length = 351 Score = 28.8 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 22/75 (29%), Gaps = 10/75 (13%) Query: 297 SSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIP 356 + + D+ L H + +Q R N + D A GLD Sbjct: 46 NRVRLQDEAELFVLLADVQALTDHFDRPEQVRENVLA----------VALDYLAAGLDPQ 95 Query: 357 AVDWIIQFDPPDDPR 371 ++Q P+ Sbjct: 96 KTTCVVQSAVPELAE 110 >1EU1-A nrPDB Length = 780 Score = 28.4 bits (62), Expect = 6.6, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 23/58 (39%), Gaps = 2/58 (3%) Query: 69 QARTIPPLLAGRDVLGAAKTGSGKT--LAFLIPAIELLHSLKFKPRNGTGIIVITPTR 124 Q P ++ D++ KT + ++IP +K GT +I I P R Sbjct: 167 QQTAWPVVVENTDLMVFWAADPMKTNEIGWVIPDHGAYAGMKALKEKGTRVICINPVR 224 >5FL3-A nrPDB Length = 368 Score = 28.4 bits (62), Expect = 6.8, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 25/63 (39%), Gaps = 19/63 (30%) Query: 38 TTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGK--TLA 95 + + FE L L + ++++ R + +L TGSGK TLA Sbjct: 109 SEVIPSFEALGLPREVMESLAAK---------ERGL--------ILVTGPTGSGKSTTLA 151 Query: 96 FLI 98 LI Sbjct: 152 ALI 154 >3S1A-A nrPDB Length = 525 Score = 28.4 bits (62), Expect = 7.5, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 21/47 (44%), Gaps = 6/47 (12%) Query: 54 LKAIEKMG--FTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLI 98 +AI KM + +P GR L + +G+GKTL F I Sbjct: 15 HQAIAKMRTMIEGFDDISHGGLPI---GRSTLVSGTSGTGKTL-FSI 57 >6GAZ-Aa nrPDB Length = 382 Score = 28.4 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 52/142 (36%), Gaps = 21/142 (14%) Query: 122 PTRELALQIF-----GVARELMEFHSQTFGIVIGGANRRQE--AEKLMKGV--------N 166 PT +L Q A E + + ++ A +K+++G + Sbjct: 123 PTYKLMTQAQLEEATKQAVEAAKVRLKMPPVLEERAPINDVLAEDKILEGTETAKYVFTD 182 Query: 167 MLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIK--ILPNEDRQS 224 + + P R + + +E DR++++ F E R+I+ I E+ Q+ Sbjct: 183 ISYSIPHRERFIVVREPSGTLRKASW---EERDRMIQVYFPREGRRILTPVIFKEENLQT 239 Query: 225 MLFSATQTTKVEDLARISLRPG 246 ++S Q V +L P Sbjct: 240 -MYSQDQHVDVLNLCVAQFEPD 260 >4TLD-A nrPDB Length = 253 Score = 28.0 bits (61), Expect = 8.7, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 21/47 (44%), Gaps = 6/47 (12%) Query: 54 LKAIEKMG--FTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLI 98 +AI KM + +P GR L + +G+GKTL F I Sbjct: 15 HQAIAKMRTMIEGFDDISHGGLPI---GRSTLVSGTSGTGKTL-FSI 57 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.140 0.384 Lambda K H 0.267 0.0432 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,435,206 Number of Sequences: 36641 Number of extensions: 831324 Number of successful extensions: 3286 Number of sequences better than 10.0: 179 Number of HSP's better than 10.0 without gapping: 176 Number of HSP's successfully gapped in prelim test: 91 Number of HSP's that attempted gapping in prelim test: 2467 Number of HSP's gapped (non-prelim): 352 length of query: 505 length of database: 10,336,785 effective HSP length: 101 effective length of query: 404 effective length of database: 6,636,044 effective search space: 2680961776 effective search space used: 2680961776 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.0 bits)