BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q03426 (396 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2R3V-A nrPDB 802 0.0 2R42-A nrPDB 613 e-176 4HAC-B nrPDB 109 2e-24 1KKH-A nrPDB 86 2e-17 2HFU-A nrPDB 62 4e-10 2X7I-A nrPDB 57 2e-08 1WUU-A nrPDB 42 4e-04 2AJ4-A nrPDB 38 0.009 2A2C-A nrPDB 37 0.013 3V5R-A nrPDB 35 0.068 2OI2-A nrPDB 35 0.084 3K85-A nrPDB 34 0.11 2DEI-A nrPDB 29 3.4 4PJ1-A nrPDB 28 7.0 3RC8-A nrPDB 28 8.0 >2R3V-A nrPDB Length = 396 Score = 802 bits (2072), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/396 (100%), Positives = 396/396 (100%) Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60 Query: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC Sbjct: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120 Query: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE Sbjct: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180 Query: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP Sbjct: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240 Query: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM Sbjct: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300 Query: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL Sbjct: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 Query: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL 396 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL Sbjct: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL 396 >2R42-A nrPDB Length = 395 Score = 613 bits (1581), Expect = e-176, Method: Compositional matrix adjust. Identities = 322/393 (81%), Positives = 355/393 (90%) Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60 MLSEVLLVSAPGKVILHGEHAVVHGKVALAV+LNLRTFL L+P SNGKV L+LPN+GIK+ Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 Query: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120 WDVA LQ LDT FLEQGDV PT EQ+EKLK+VAGLP DC E L++LAFLYLYL+IC Sbjct: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 Query: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180 RKQR LPSLDI+VWSELPPGAGLGSSAAYSVC+AAALLT CEE+ NPLKD + W +E Sbjct: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 Query: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240 DL+ INKWA++GER+IHGNPSGVDN+VSTWGGALRY QGK+SSLKR PALQILLTNTKVP Sbjct: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240 Query: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300 R+T+ALVAGVR+RL+KFPEI+APLLTSIDAISLECERVLGEM AP PEQYLVLEEL+DM Sbjct: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300 Query: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 NQHHLNALGVGHASLDQLCQVT A GLHSKLTGAGGGGCGITLLKPGLE+ +VEA KQAL Sbjct: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 Query: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQAL 393 T CGFDC ETSIGAPGVS+HSATS++ V+QAL Sbjct: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQAL 393 >4HAC-B nrPDB Length = 321 Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 106/347 (30%), Positives = 156/347 (44%), Gaps = 77/347 (22%) Query: 3 SEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAW 62 S ++ SAPGK+ L GEHAVV+G+ A+A ++ LRT +R + Sbjct: 19 SHMVSCSAPGKIYLFGEHAVVYGETAIACAVELRTRVRAE-------------------- 58 Query: 63 DVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRK 122 L+ S Q + T EK P AV E++ RK Sbjct: 59 -------LNDSITIQSQIGR-TGLDFEKH------PYVSAVIEKM-------------RK 91 Query: 123 QRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDL 182 + + + V S++P G+GLGSSAA ++ AL N L Sbjct: 92 SIPINGVFLTVDSDIPVGSGLGSSAAVTIASIGAL-----------------NELFGFGL 134 Query: 183 EL--INKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240 L I K + E + G S D VST+GG + + + LK +P I++ +T V Sbjct: 135 SLQEIAKLGHEIEIKVQGAASPTDTYVSTFGGVVTIPERR--KLK-TPDCGIVIGDTGVF 191 Query: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300 +T+ LVA VR +P+++ PL+TSI IS E+++ Y + L+++ Sbjct: 192 SSTKELVANVRQLRESYPDLIEPLMTSIGKISRIGEQLV-------LSGDYASIGRLMNV 244 Query: 301 NQHHLNALGVGHASLDQLCQVTRARG-LHSKLTGAGGGGCGITLLKP 346 NQ L+ALGV L QL RA G +K+TGAGGGGC + L P Sbjct: 245 NQGLLDALGVNILELSQLIYSARAAGAFGAKITGAGGGGCMVALTAP 291 >1KKH-A nrPDB Length = 317 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 81/341 (23%), Positives = 145/341 (42%), Gaps = 57/341 (16%) Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVA 65 +++ P KVIL GEHAVV+G A++++++L + + ++ ++ L+L ++ ++ Sbjct: 6 MIIETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKETQEDEIILNLNDLNKSLGLNLN 65 Query: 66 RLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRA 125 +++++ + GD CA+ L YL+I K Sbjct: 66 EIKNINPNNF--GDFKYCL----------------CAIKNTLD-------YLNIEPK--- 97 Query: 126 LPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELI 185 I + S++P GLGSSA+ ++ A+ N+ K+D I Sbjct: 98 -TGFKINISSKIPISCGLGSSASITIGTIKAV-------------SGFYNKELKDDE--I 141 Query: 186 NKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRA 245 K + E+ I G S D + T+ G L K +K + +N + Sbjct: 142 AKLGYMVEKEIQGKASITDTSTITYKGILEIKNNKFRKIKGEFE--------EFLKNCKF 193 Query: 246 LVAGVRNRLLKFPEIVAPL--LTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQH 303 L+ R K E+V + + + D I E ++V+ E + E + +L+ N Sbjct: 194 LIVYAEKRKKKTAELVNEVAKIENKDEIFKEIDKVIDEALKIKNKEDF---GKLMTKNHE 250 Query: 304 HLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLL 344 L L + LD++ + G +KLTGAGGGGC I L+ Sbjct: 251 LLKKLNISTPKLDRIVDIGNRFGFGAKLTGAGGGGCVIILV 291 >2HFU-A nrPDB Length = 332 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 87/333 (26%), Positives = 129/333 (38%), Gaps = 58/333 (17%) Query: 12 GKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLD 71 GKVIL GEH VVHG A+ ++ T RL+ ++ +P LQ D Sbjct: 20 GKVILFGEHFVVHGAEAIVAGISEYTECRLE------INPGVPG-----------LQVDD 62 Query: 72 TSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDI 131 G + EQ++ + VL L + LS L + Sbjct: 63 QRPAIPGYIAQKRDEQIKAHQ---------------LVLDHLKVDLS-------GDGLKM 100 Query: 132 VVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQ 191 + L P +G+G+SA+ V + AL E L D E +N AF Sbjct: 101 FIGGPLVPSSGIGASASDVVAFSRAL---SELYQLNLTD------------EEVNLSAFV 145 Query: 192 GERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVR 251 GE HG PSG DN +T+GG + Y + S+ + A Q L V A A V Sbjct: 146 GEGGYHGTPSGADNTAATYGGLILYRRQNGKSVFKPIAFQQRLYLVVVGTGINASTAKVV 205 Query: 252 NRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVG 311 N + K + P+ + ++ + EA L +L++ N + V Sbjct: 206 NDVHKMKQ-QQPV--QFKRLYDNYTHIVSQAREALQKGDLQRLGQLMNANHDLCRQIDVS 262 Query: 312 HASLDQLCQVTRARG-LHSKLTGAGGGGCGITL 343 L+ + Q R G L +KL+G G GG + L Sbjct: 263 CRELESIVQTCRTYGALGAKLSGTGRGGIAVAL 295 >2X7I-A nrPDB Length = 308 Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 84/340 (24%), Positives = 139/340 (40%), Gaps = 73/340 (21%) Query: 10 APGKVILHGEHAVVHGKVALAVSLNL-RTFLRLQPHSNGKVDLSLPNIGIKRAWDVA-RL 67 + GK+IL GEHAV G+ A+AV N + + ++ +G ++ +D L Sbjct: 11 STGKIILIGEHAVTFGEPAIAVPFNAGKIKVLIEALESGNYSSIKSDVYDGMLYDAPDHL 70 Query: 68 QSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALP 127 +SL F+E ++T P Sbjct: 71 KSLVNRFVELNNITEP-------------------------------------------- 86 Query: 128 SLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINK 187 L + + + LPP GLGSSAA +V A + TKE+L Sbjct: 87 -LAVTIQTNLPPSRGLGSSAAVAVAFVRASYDFLGK------------SLTKEELIEKAN 133 Query: 188 WAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKR-SPALQILLTNTKVPRNTRAL 246 WA E++ HG PSG+D G + + +G +LK S +++ +T V +TR Sbjct: 134 WA---EQIAHGKPSGIDTQTIVSGKPVWFQKGHAETLKTLSLDGYMVVIDTGVKGSTRQA 190 Query: 247 VAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLN 306 V V ++L + P+ ++ + I + L V+ ++ L ++ + L Sbjct: 191 VHDV-HKLCEDPQYMSHV-KHIGKLVLRASDVI-------EHHKFEALADIFNECHADLK 241 Query: 307 ALGVGHASLDQLCQVTRARG-LHSKLTGAGGGGCGITLLK 345 AL V H ++QL ++ + G + KLTGAG GG + L K Sbjct: 242 ALTVSHDKIEQLMKIGKENGAIAGKLTGAGRGGSMLLLAK 281 >1WUU-A nrPDB Length = 399 Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 101/375 (26%), Positives = 145/375 (38%), Gaps = 82/375 (21%) Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVA 65 L VSAPG+V L GEH + + L ++L L T L P +G V L + G A + Sbjct: 37 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEG---ADEPQ 93 Query: 66 RLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLA--VLAFLYLYLSICRKQ 123 RLQ PT+++ + G P R A V + Y + Sbjct: 94 RLQ-----------FPLPTAQRSLE----PGTP-------RWANYVKGVIQYYPAA---- 127 Query: 124 RALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLE 183 LP VV S +P G GL SSA+ V L +C + G R Sbjct: 128 -PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPD------SGTIAAR------- 173 Query: 184 LINKWAFQGERMIHGNPSGV-DNAVSTWGGALRYHQGKISSLKRS------PALQILLTN 236 + Q E G P G+ D +S G SL+ S P L +L+TN Sbjct: 174 --AQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITN 231 Query: 237 TKVPRNTRALVAGVRNRLLKFPEIVAPL----LTSIDAISLECER-------------VL 279 + V + + VR R + E+ L L + LE R V+ Sbjct: 232 SNVRHSLASSEYPVRRR--QCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVV 289 Query: 280 GEM---GEAPAPEQ---YLVLEELIDMNQHHL-NALGVGHASLDQLCQVTRA-RGLH-SK 330 GE+ +A A + Y L+ + L + V LDQL + A G++ S+ Sbjct: 290 GEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSR 349 Query: 331 LTGAGGGGCGITLLK 345 +TG G GGC +TLL+ Sbjct: 350 MTGGGFGGCTVTLLE 364 >2AJ4-A nrPDB Length = 548 Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 31/49 (63%), Gaps = 2/49 (4%) Query: 315 LDQLCQVTRARGLH-SKLTGAGGGGCGITLLKPGLEQPEVEATKQALTS 362 +D++C + + G + S+LTGAG GGC + L+ PG +E K+AL + Sbjct: 468 IDKICSIALSNGSYGSRLTGAGWGGCTVHLV-PGGPNGNIEKVKEALAN 515 >2A2C-A nrPDB Length = 478 Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust. Identities = 26/63 (41%), Positives = 37/63 (58%), Gaps = 7/63 (11%) Query: 287 APEQYL-VLEELIDMNQHHLNALGVGHAS---LDQLCQVTRARGLH-SKLTGAGGGGCGI 341 APE + +L EL MNQ H++ + S LDQL + R G S+LTGAG GGC + Sbjct: 372 APENMVQLLGEL--MNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTV 429 Query: 342 TLL 344 +++ Sbjct: 430 SMV 432 >3V5R-A nrPDB Length = 505 Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust. Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 2/46 (4%) Query: 316 DQLCQVTRARG-LHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 +Q+C + A G S+LTGAG GGC I L+ P VE ++AL Sbjct: 426 NQICSIALANGSFGSRLTGAGWGGCTIHLV-PSGANGNVEQVRKAL 470 >2OI2-A nrPDB Length = 292 Score = 34.7 bits (78), Expect = 0.084, Method: Compositional matrix adjust. Identities = 49/213 (23%), Positives = 93/213 (43%), Gaps = 30/213 (14%) Query: 135 SELPPGAGLGSSAAYSVCLAAALLTVCE-EIPNPLKDGDCVNRWTKEDLELINKWAFQGE 193 S +P G+GSSAA S+ A+ + ++P+ + + VNR E Sbjct: 81 SAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLE-ILVNR---------------AE 124 Query: 194 RMIHGNPSGVDNAVSTWGGALRYHQG-KISSLKRSPALQILLTNTKVPRNTRALVAGVRN 252 + H NPSG+D +R+ + + L+ + +++ +T V +TR + V+N Sbjct: 125 MIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQN 184 Query: 253 RLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGH 312 + + P L ++ ++ + E + + L +++ HL +GV Sbjct: 185 K----GKDALPFLHALGELTQQAEIAISQKDAEG-------LGQILSQAHLHLKEIGVSS 233 Query: 313 ASLDQLCQVTRARG-LHSKLTGAGGGGCGITLL 344 D L + + G L +K++G G GGC I L+ Sbjct: 234 LEADSLVETALSHGALGAKMSGGGLGGCIIALV 266 >3K85-A nrPDB Length = 357 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 4/57 (7%) Query: 115 LYLSICRKQRALP-SLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKD 170 +Y I R R P S I +++ P G+GLG+S+ VC+ A + E + PL D Sbjct: 84 VYNRIIRDYRLEPKSFKITTYNDAPAGSGLGTSSTMVVCILKAFI---EWLSLPLGD 137 >2DEI-A nrPDB Length = 350 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 2/68 (2%) Query: 5 VLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDV 64 ++ V +PG+V L GEH + +++NL T +++ +G+V L + G +R + + Sbjct: 1 MIKVKSPGRVNLIGEHTDYTYGYVMPMAINLYT--KIEAEKHGEVILYSEHFGEERKFSL 58 Query: 65 ARLQSLDT 72 L+ ++ Sbjct: 59 NDLRKENS 66 >4PJ1-A nrPDB Length = 558 Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust. Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 9/78 (11%) Query: 31 VSLNLRTFLRLQPHSNGKVDLSLPN----IGIKRAWDVARLQSLDTSFLEQGDVTTPTSE 86 ++LNL +QPH GKV + + +K D A+++ +EQ DVTT E Sbjct: 332 LTLNLED---VQPHDLGKVGKVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYE 388 Query: 87 QVEKLKE-VAGLPDDCAV 103 + EKL E +A L D AV Sbjct: 389 K-EKLNERLAKLSDGVAV 405 >3RC8-A nrPDB Length = 677 Score = 27.7 bits (60), Expect = 8.0, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 22 VVHGKVALAVSLNLRTFLR---LQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQG 78 V + + ++L++R + ++P N K + L I +A +A +S ++G Sbjct: 377 VATDAIGMGLNLSIRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRFKEG 436 Query: 79 DVTTPTSEQVEKLKEVAGLPDD 100 +VTT E + LKE+ P D Sbjct: 437 EVTTMNHEDLSLLKEILKRPVD 458 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2R3V-A nrPDB 543 e-155 2R42-A nrPDB 495 e-140 1KKH-A nrPDB 273 8e-74 2HFU-A nrPDB 251 4e-67 4HAC-B nrPDB 243 1e-64 1WUU-A nrPDB 224 4e-59 2X7I-A nrPDB 215 2e-56 Sequences not found previously or not previously below threshold: 2DEI-A nrPDB 113 1e-25 1S4E-A nrPDB 107 9e-24 2OI2-A nrPDB 95 4e-20 2A2C-A nrPDB 86 3e-17 1PIE-A nrPDB 84 8e-17 2AJ4-A nrPDB 73 2e-13 3V5R-A nrPDB 68 7e-12 4N3O-A nrPDB 58 1e-08 5YYS-A nrPDB 57 1e-08 3K85-A nrPDB 52 4e-07 4UT4-A nrPDB 52 5e-07 3K17-A nrPDB 48 6e-06 4P52-A nrPDB 41 8e-04 3GON-A nrPDB 37 0.018 4RPF-A nrPDB 36 0.026 3HUL-A nrPDB 34 0.098 2V2V-A nrPDB 33 0.26 4JF0-A nrPDB 29 3.7 3UY5-A nrPDB 28 5.5 >2R3V-A nrPDB Length = 396 Score = 543 bits (1398), Expect = e-155, Method: Composition-based stats. Identities = 396/396 (100%), Positives = 396/396 (100%) Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60 Query: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC Sbjct: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120 Query: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE Sbjct: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180 Query: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP Sbjct: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240 Query: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM Sbjct: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300 Query: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL Sbjct: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 Query: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL 396 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL Sbjct: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL 396 >2R42-A nrPDB Length = 395 Score = 495 bits (1273), Expect = e-140, Method: Composition-based stats. Identities = 322/393 (81%), Positives = 355/393 (90%) Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60 MLSEVLLVSAPGKVILHGEHAVVHGKVALAV+LNLRTFL L+P SNGKV L+LPN+GIK+ Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQ 60 Query: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120 WDVA LQ LDT FLEQGDV PT EQ+EKLK+VAGLP DC E L++LAFLYLYL+IC Sbjct: 61 VWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAIC 120 Query: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180 RKQR LPSLDI+VWSELPPGAGLGSSAAYSVC+AAALLT CEE+ NPLKD + W +E Sbjct: 121 RKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEE 180 Query: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240 DL+ INKWA++GER+IHGNPSGVDN+VSTWGGALRY QGK+SSLKR PALQILLTNTKVP Sbjct: 181 DLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVP 240 Query: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300 R+T+ALVAGVR+RL+KFPEI+APLLTSIDAISLECERVLGEM AP PEQYLVLEEL+DM Sbjct: 241 RSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDM 300 Query: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 NQHHLNALGVGHASLDQLCQVT A GLHSKLTGAGGGGCGITLLKPGLE+ +VEA KQAL Sbjct: 301 NQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQAL 360 Query: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQAL 393 T CGFDC ETSIGAPGVS+HSATS++ V+QAL Sbjct: 361 TGCGFDCWETSIGAPGVSMHSATSIEDPVRQAL 393 >1KKH-A nrPDB Length = 317 Score = 273 bits (698), Expect = 8e-74, Method: Composition-based stats. Identities = 81/341 (23%), Positives = 145/341 (42%), Gaps = 57/341 (16%) Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVA 65 +++ P KVIL GEHAVV+G A++++++L + + ++ ++ L+L ++ ++ Sbjct: 6 MIIETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKETQEDEIILNLNDLNKSLGLNLN 65 Query: 66 RLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRA 125 +++++ + GD CA+ L YL+I K Sbjct: 66 EIKNINPNNF--GDFKYCL----------------CAIKNTLD-------YLNIEPK--- 97 Query: 126 LPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELI 185 I + S++P GLGSSA+ ++ A+ N+ K+D I Sbjct: 98 -TGFKINISSKIPISCGLGSSASITIGTIKAV-------------SGFYNKELKDD--EI 141 Query: 186 NKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRA 245 K + E+ I G S D + T+ G L K +K + +N + Sbjct: 142 AKLGYMVEKEIQGKASITDTSTITYKGILEIKNNKFRKIKGEFE--------EFLKNCKF 193 Query: 246 LVAGVRNRLLKFPEIVAPL--LTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQH 303 L+ R K E+V + + + D I E ++V+ E + E + +L+ N Sbjct: 194 LIVYAEKRKKKTAELVNEVAKIENKDEIFKEIDKVIDEALKIKNKEDF---GKLMTKNHE 250 Query: 304 HLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLL 344 L L + LD++ + G +KLTGAGGGGC I L+ Sbjct: 251 LLKKLNISTPKLDRIVDIGNRFGFGAKLTGAGGGGCVIILV 291 >2HFU-A nrPDB Length = 332 Score = 251 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 87/343 (25%), Positives = 132/343 (38%), Gaps = 58/343 (16%) Query: 12 GKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLD 71 GKVIL GEH VVHG A+ ++ T RL+ ++ +P LQ D Sbjct: 20 GKVILFGEHFVVHGAEAIVAGISEYTECRLE------INPGVPG-----------LQVDD 62 Query: 72 TSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDI 131 G + EQ++ + VL L + LS L + Sbjct: 63 QRPAIPGYIAQKRDEQIKAHQ---------------LVLDHLKVDLS-------GDGLKM 100 Query: 132 VVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQ 191 + L P +G+G+SA+ V + AL E L D E +N AF Sbjct: 101 FIGGPLVPSSGIGASASDVVAFSRAL---SELYQLNLTD------------EEVNLSAFV 145 Query: 192 GERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVR 251 GE HG PSG DN +T+GG + Y + S+ + A Q L V A A V Sbjct: 146 GEGGYHGTPSGADNTAATYGGLILYRRQNGKSVFKPIAFQQRLYLVVVGTGINASTAKVV 205 Query: 252 NRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVG 311 N + K + P+ + ++ + EA L +L++ N + V Sbjct: 206 NDVHKMKQ-QQPV--QFKRLYDNYTHIVSQAREALQKGDLQRLGQLMNANHDLCRQIDVS 262 Query: 312 HASLDQLCQVTRARG-LHSKLTGAGGGGCGITLLKPGLEQPEV 353 L+ + Q R G L +KL+G G GG + L ++ + Sbjct: 263 CRELESIVQTCRTYGALGAKLSGTGRGGIAVALAASSDQRDAI 305 >4HAC-B nrPDB Length = 321 Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 106/363 (29%), Positives = 159/363 (43%), Gaps = 77/363 (21%) Query: 3 SEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAW 62 S ++ SAPGK+ L GEHAVV+G+ A+A ++ LRT +R + Sbjct: 19 SHMVSCSAPGKIYLFGEHAVVYGETAIACAVELRTRVRAE-------------------- 58 Query: 63 DVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRK 122 L+ S Q + T EK P AV E++ RK Sbjct: 59 -------LNDSITIQSQIGR-TGLDFEKH------PYVSAVIEKM-------------RK 91 Query: 123 QRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDL 182 + + + V S++P G+GLGSSAA ++ AL + L Sbjct: 92 SIPINGVFLTVDSDIPVGSGLGSSAAVTIASIGALNELFG---------------FGLSL 136 Query: 183 ELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRN 242 + I K + E + G S D VST+GG + + LK P I++ +T V + Sbjct: 137 QEIAKLGHEIEIKVQGAASPTDTYVSTFGGVVTIPER--RKLKT-PDCGIVIGDTGVFSS 193 Query: 243 TRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQ 302 T+ LVA VR +P+++ PL+TSI IS E+++ Y + L+++NQ Sbjct: 194 TKELVANVRQLRESYPDLIEPLMTSIGKISRIGEQLV-------LSGDYASIGRLMNVNQ 246 Query: 303 HHLNALGVGHASLDQLCQVTRARG-LHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALT 361 L+ALGV L QL RA G +K+TGAGGGGC + L P + +A+ Sbjct: 247 GLLDALGVNILELSQLIYSARAAGAFGAKITGAGGGGCMVALTAP----EKCNQVAEAVA 302 Query: 362 SCG 364 G Sbjct: 303 GAG 305 >1WUU-A nrPDB Length = 399 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 98/373 (26%), Positives = 138/373 (36%), Gaps = 78/373 (20%) Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVA 65 L VSAPG+V L GEH + + L ++L L T L P +G V L + G A + Sbjct: 37 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEG---ADEPQ 93 Query: 66 RLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRA 125 RLQ PT+++ + G P V + Y + Sbjct: 94 RLQ-----------FPLPTAQRSLE----PGTPRWANY-----VKGVIQYYPAA-----P 128 Query: 126 LPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELI 185 LP VV S +P G GL SSA+ V L +C + G R Sbjct: 129 LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPD------SGTIAAR--------- 173 Query: 186 NKWAFQGERMIHGNPSGV-DNAVSTWGGALRYHQGKISSLKRS------PALQILLTNTK 238 + Q E G P G+ D +S G SL+ S P L +L+TN+ Sbjct: 174 AQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSN 233 Query: 239 VPRNTRALVAGVRNRLLKFPEIVAPL----LTSIDAISLECER-------------VLGE 281 V + + VR R + E+ L L + LE R V+GE Sbjct: 234 VRHSLASSEYPVRRR--QCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGE 291 Query: 282 ------MGEAPAPEQYLVLEELIDMNQHHL-NALGVGHASLDQLCQVTRA-RGL-HSKLT 332 A Y L+ + L + V LDQL + A G+ S++T Sbjct: 292 IRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMT 351 Query: 333 GAGGGGCGITLLK 345 G G GGC +TLL+ Sbjct: 352 GGGFGGCTVTLLE 364 >2X7I-A nrPDB Length = 308 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 84/341 (24%), Positives = 139/341 (40%), Gaps = 73/341 (21%) Query: 9 SAPGKVILHGEHAVVHGKVALAVSLNL-RTFLRLQPHSNGKVDLSLPNIGIKRAWDVA-R 66 + GK+IL GEHAV G+ A+AV N + + ++ +G ++ +D Sbjct: 10 ESTGKIILIGEHAVTFGEPAIAVPFNAGKIKVLIEALESGNYSSIKSDVYDGMLYDAPDH 69 Query: 67 LQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRAL 126 L+SL F+E ++T P Sbjct: 70 LKSLVNRFVELNNITEP------------------------------------------- 86 Query: 127 PSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELIN 186 L + + + LPP GLGSSAA +V A + TKE+L Sbjct: 87 --LAVTIQTNLPPSRGLGSSAAVAVAFVRASYDFLGK------------SLTKEELIEKA 132 Query: 187 KWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKR-SPALQILLTNTKVPRNTRA 245 WA E++ HG PSG+D G + + +G +LK S +++ +T V +TR Sbjct: 133 NWA---EQIAHGKPSGIDTQTIVSGKPVWFQKGHAETLKTLSLDGYMVVIDTGVKGSTRQ 189 Query: 246 LVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHL 305 V V ++L + P+ ++ + I + L V+ ++ L ++ + L Sbjct: 190 AVHDV-HKLCEDPQYMSHV-KHIGKLVLRASDVI-------EHHKFEALADIFNECHADL 240 Query: 306 NALGVGHASLDQLCQVTRARG-LHSKLTGAGGGGCGITLLK 345 AL V H ++QL ++ + G + KLTGAG GG + L K Sbjct: 241 KALTVSHDKIEQLMKIGKENGAIAGKLTGAGRGGSMLLLAK 281 >2DEI-A nrPDB Length = 350 Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 70/366 (19%), Positives = 116/366 (31%), Gaps = 79/366 (21%) Query: 5 VLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDV 64 ++ V +PG+V L GEH + +++NL T + + H G+V L + G +R + + Sbjct: 1 MIKVKSPGRVNLIGEHTDYTYGYVMPMAINLYTKIEAEKH--GEVILYSEHFGEERKFSL 58 Query: 65 ARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQR 124 L+ E + ++ + Sbjct: 59 NDLR-----------------------------------KENSWIDYVKGIFWVLKESDY 83 Query: 125 ALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLEL 184 + + V LP GAGL SSA++ V + L + K D Sbjct: 84 EVGGIKGRVSGNLPLGAGLSSSASFEVGILETLDKLYN---------------LKLDSLS 128 Query: 185 INKWAFQGERMIHGNPSGV-DNAVSTWGGALRY-----HQGKISSLKRSPALQILLTNTK 238 A + E G P G+ D +G H + + IL+ T Sbjct: 129 KVLLAKKAENEFVGVPCGILDQFAVVFGREGNVIFLDTHTLDYEYIPFPKDVSILVFYTG 188 Query: 239 VPRNTRALVAGVRNRLLK----------FPEIVA-------PLLTS-IDAISLECERVLG 280 V R + R + + E+ PL I E RVL Sbjct: 189 VRRELASSEYAERKHIAEESLKILGKGSSKEVREGELSKLPPLHRKFFGYIVRENARVL- 247 Query: 281 EMGEAPAPEQYLVLEELIDMNQ-HHLNALGVGHASLDQLCQVTRARG-LHSKLTGAGGGG 338 E+ +A + +++ V LD + G ++LTGAG GG Sbjct: 248 EVRDALKEGNVEEVGKILTTAHWDLAKNYEVSCKELDFFVERALKLGAYGARLTGAGFGG 307 Query: 339 CGITLL 344 I L+ Sbjct: 308 SAIALV 313 >1S4E-A nrPDB Length = 352 Score = 107 bits (266), Expect = 9e-24, Method: Composition-based stats. Identities = 67/365 (18%), Positives = 114/365 (31%), Gaps = 79/365 (21%) Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVA 65 + V +PG+V L GEH + ++++L T + + + Sbjct: 4 ITVKSPGRVNLIGEHTDYTYGYVMPMAIDLYTIITAEKYD-------------------- 43 Query: 66 RLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRA 125 ++Q F E+ T D E + + + ++ Sbjct: 44 KVQLYSEHFNEEKTFTL-----------------DNLTKEGSWIDYVKGVLWVLIQEGYK 86 Query: 126 LPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELI 185 + L + +LP GAGL SSA++ V + L + +PLK Sbjct: 87 IGGLKGKITGDLPLGAGLSSSASFEVGILEVLNQLYNLNIDPLKKALLAK---------- 136 Query: 186 NKWAFQGERMIHGNPSGV-DNAVSTWGGA-----LRYHQGKISSLKRSPALQILLTNTKV 239 + E G P G+ D +G L + + + +L+ T V Sbjct: 137 -----KAENEFVGVPCGILDQFAVVFGKKDNVIFLDTQTLQYEYIPFPKDVSVLVFYTGV 191 Query: 240 PRNTRALVAGVRNR----------LLKFPEIVA-------PLLTS-IDAISLECERVLGE 281 R + R R E+ PL I E RVL E Sbjct: 192 KRELASSEYAERKRIAEESLRILGKESSKEVTEKDLGKLPPLHRKFFSYIVRENARVL-E 250 Query: 282 MGEAPAPEQYLVLEELIDMNQ-HHLNALGVGHASLDQLCQVTRARG-LHSKLTGAGGGGC 339 + +A + +++ V LD + G ++LTGAG GG Sbjct: 251 VRDALKEGDIEKVGKILTTAHWDLAENYRVSCEELDFFVKKAMELGAYGARLTGAGFGGS 310 Query: 340 GITLL 344 I L+ Sbjct: 311 AIALV 315 >2OI2-A nrPDB Length = 292 Score = 95.0 bits (234), Expect = 4e-20, Method: Composition-based stats. Identities = 68/347 (19%), Positives = 124/347 (35%), Gaps = 84/347 (24%) Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSL-NLRTFLRLQPHSNGKVDLSLPNIGIK 59 M +V + A K+IL GEHAVV+G A+++ L + ++ +P Sbjct: 1 MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKV-----------VPAESPW 49 Query: 60 RAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSI 119 R ++ L + +Y S+ Sbjct: 50 RLYEEDTLS--------------------------------------------MAVYASL 65 Query: 120 CRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTK 179 + + S +P G+GSSAA S+ A+ + VNR Sbjct: 66 EYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNR--- 122 Query: 180 EDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRY-HQGKISSLKRSPALQILLTNTK 238 E + H NPSG+D +R+ + L+ + +++ +T Sbjct: 123 ------------AEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTG 170 Query: 239 VPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELI 298 V +TR + V+N+ P L ++ ++ + E + + + L +++ Sbjct: 171 VYGHTREAIQVVQNKGKD----ALPFLHALGELTQQAEIAISQ-------KDAEGLGQIL 219 Query: 299 DMNQHHLNALGVGHASLDQLCQVTRARG-LHSKLTGAGGGGCGITLL 344 HL +GV D L + + G L +K++G G GGC I L+ Sbjct: 220 SQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALV 266 >2A2C-A nrPDB Length = 478 Score = 85.8 bits (210), Expect = 3e-17, Method: Composition-based stats. Identities = 63/378 (16%), Positives = 114/378 (30%), Gaps = 44/378 (11%) Query: 8 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDL-SLPNIGIKRAWDVAR 66 V APG+V + GEH G L +++ + ++P + L + + + Sbjct: 58 VRAPGRVNIIGEHIDYCGYSVLPMAVEQDVLIAVEPVKTYALQLANTNPLYPDFSTSANN 117 Query: 67 LQSLDTSFLEQGDV--TTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQR 124 +Q T L ++ L + G+ + L C Sbjct: 118 IQIDKTKPLWHNYFLCGLKGIQEHFGLSNLTGMNCLVDGNIPPSSGLSSSSALVCCAGLV 177 Query: 125 ALPSLDIVVWSELPP--------------GAGLGSSAAYSVCLAAA-LLTVCEEIPNPLK 169 L L + S++ G G+ S ++ A L+ +K Sbjct: 178 TLTVLGRNL-SKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVK 236 Query: 170 DGDCVNRWTKEDLELINKWA------FQGERMIHGNPSGVDNAVSTWGGALRYHQGKISS 223 +NK A E + W LR + + Sbjct: 237 LPSGAVFVIANSCVEMNKAATSHFNIRVMECRLAAK-LLAKYKSLQWDKVLRLEEVQA-K 294 Query: 224 LKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTS------IDAISLECER 277 L S +L+T + R + E+ +L+ I + + Sbjct: 295 LGISLEEMLLVTEDALHPEPYNPEEICRCLGISLEELRTQILSPNTQDVLIFKLYQRAKH 354 Query: 278 VLGEMGEAPAPEQY---------LVLEELIDMNQHHLNA-LGVGHASLDQLCQVTRARGL 327 V E ++ +L EL++ + LDQL + R G Sbjct: 355 VYSEAARVLQFKKICEEAPENMVQLLGELMNQSHMSCRDMYECSCPELDQLVDICRKFGA 414 Query: 328 -HSKLTGAGGGGCGITLL 344 S+LTGAG GGC ++++ Sbjct: 415 QGSRLTGAGWGGCTVSMV 432 >1PIE-A nrPDB Length = 419 Score = 84.2 bits (206), Expect = 8e-17, Method: Composition-based stats. Identities = 59/372 (15%), Positives = 116/372 (31%), Gaps = 81/372 (21%) Query: 10 APGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQS 69 +PG++ L GEH +G S+ + T + + KV + Sbjct: 53 SPGRINLIGEHTDYNGGYVFPASITIGTTGLARLREDKKV------------------KL 94 Query: 70 LDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSL 129 +F + G + E +K E + + + Sbjct: 95 YSENFPKLGVIEFDLDEVEKKDG------------ELWSNYVKGMIVMLKGAGYEIDKGF 142 Query: 130 DIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWA 189 ++++ E+P +GL SSA+ + + L + L + + Sbjct: 143 ELLIKGEIPTASGLSSSASLELLVGVVLDDLFNLNVPRL---------------ELVQLG 187 Query: 190 FQGERMIHGNPSGV-DNAVSTWGGALRYHQGKISSLKRSP------ALQILLTNTKVPRN 242 + E G SG+ D +G + + ++LK I++ NT PR Sbjct: 188 QKTENDYIGVNSGILDQFAIGFGEVKKAIELDCNTLKYEMVPVELRDYDIVIMNTNKPRA 247 Query: 243 TRALVAGVRN-------RLLKFPEIVAPLLTSIDAISLECERVLGE-------------- 281 R + ++ + L + ++G+ Sbjct: 248 LTESKYNERFAETREALKRMQTRLDIQSLGELSNEEFDANTDLIGDETLIKRARHAVYEN 307 Query: 282 -----MGEAPAPEQYLVLEELIDMNQHHL-NALGVGHASLDQLCQVTRARG--LHSKLTG 333 +A EL++ + L + V LD L + + + L +++TG Sbjct: 308 NRTKIAQKAFVAGNLTKFGELLNASHASLKDDYEVTGLELDTLAETAQKQAGVLGARMTG 367 Query: 334 AGGGGCGITLLK 345 AG GGC I L+ Sbjct: 368 AGFGGCAIALVA 379 >2AJ4-A nrPDB Length = 548 Score = 73.1 bits (177), Expect = 2e-13, Method: Composition-based stats. Identities = 27/118 (22%), Positives = 55/118 (46%), Gaps = 4/118 (3%) Query: 247 VAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLN 306 + VR ++LK + + + + L+ +++ + + L++ +Q + Sbjct: 400 TSPVRFQVLKLYQRAKHVYSESLRV-LKAVKLMTTASFTADEDFFKQFGALMNESQASCD 458 Query: 307 AL-GVGHASLDQLCQVTRARG-LHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTS 362 L +D++C + + G S+LTGAG GGC + L+ PG +E K+AL + Sbjct: 459 KLYECSCPEIDKICSIALSNGSYGSRLTGAGWGGCTVHLV-PGGPNGNIEKVKEALAN 515 Score = 57.7 bits (137), Expect = 8e-09, Method: Composition-based stats. Identities = 47/220 (21%), Positives = 78/220 (35%), Gaps = 28/220 (12%) Query: 10 APGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQS 69 +PG+V L GEH L ++++ ++ + ++L N D Q Sbjct: 70 SPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVLNEKNPSITLINA------DPKFAQR 123 Query: 70 LDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSL 129 L+ VT S GL + ++LA F L L Sbjct: 124 KFDLPLDGSYVTIDPSVSDWSNYFKCGLHVAHSFLKKLAPERF---------ASAPLAGL 174 Query: 130 DIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWA 189 + ++P G+GL SSAA+ +A A++ + +K++L I A Sbjct: 175 QVFCEGDVPTGSGLSSSAAFICAVALAVVKA---------NMGPGYHMSKQNLMRITVVA 225 Query: 190 FQGERMIHGNPSGVDNAVSTWGGALRYHQGKIS-SLKRSP 228 E + N G+D A S G + LK +P Sbjct: 226 ---EHYVGVNNGGMDQAASVCGEEDHALYVEFKPQLKATP 262 >3V5R-A nrPDB Length = 505 Score = 68.1 bits (164), Expect = 7e-12, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 61/179 (34%), Gaps = 29/179 (16%) Query: 204 DNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRL-LKFPEIVA 262 +N W G + + ++R + L+ + + + V L E Sbjct: 299 ENQAQPWNGDI------GTGIERLLKMLQLVEESFSRKKSGFTVHEASTALNCSREEFTR 352 Query: 263 ------PLLTSIDAISLECERVLGEMGEAPAPEQ-------------YLVLEELIDMNQH 303 P+ + + + V E + + L++ +Q Sbjct: 353 DYLTTFPVRFQVLKLYQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQA 412 Query: 304 HLNAL-GVGHASLDQLCQVTRARG-LHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 + L +Q+C + A G S+LTGAG GGC I L+ G VE ++AL Sbjct: 413 SCDKLYECSCIETNQICSIALANGSFGSRLTGAGWGGCTIHLVPSG-ANGNVEQVRKAL 470 Score = 58.4 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 38/248 (15%), Positives = 72/248 (29%), Gaps = 43/248 (17%) Query: 7 LVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVAR 66 + +PG+V L GEH L +++++ ++ ++L N K Sbjct: 26 IARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPK------- 78 Query: 67 LQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRAL 126 Q P + + ++L L Sbjct: 79 --------FAQRKFDLPLDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTPL 130 Query: 127 PSLDIVVWSELPPGAGLGS--SAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLEL 184 I S++P G GL S + A ++ A + + + Sbjct: 131 VGAQIFCQSDIPTGGGLSSAFTCAAALATIRA----------------NMGKNFDISKKD 174 Query: 185 INKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKIS-SLKRSP---------ALQILL 234 + + E + N G+D A S +G + LK +P + ++ Sbjct: 175 LTRITAVAEHYVGVNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQLKNHEISFVI 234 Query: 235 TNTKVPRN 242 NT V N Sbjct: 235 ANTLVKSN 242 >4N3O-A nrPDB Length = 342 Score = 57.7 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 60/344 (17%), Positives = 118/344 (34%), Gaps = 61/344 (17%) Query: 24 HGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTP 83 + L +++L L +GK+ P+ ++ D Sbjct: 31 YTGYVLNATISLYIHCTLIKREDGKIIFDSPDTNSYCEYESKEFLGND------------ 78 Query: 84 TSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGL 143 +L + +Y + ++ L S + +S++P G+GL Sbjct: 79 ---------------------GKLDIFKSIYNRIVKDFTKKPL-SFSLHTYSDVPSGSGL 116 Query: 144 GSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGV 203 G S+ V + A E + PL I K A++ ER G G Sbjct: 117 GGSSTLVVGVIKA---FAEWLNLPL------------GEYEIAKLAYEIEREDLGIVGGA 161 Query: 204 -DNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVA 262 D +T+GG ++ + + KR + + N V N + +I Sbjct: 162 QDQYAATFGG---FNFMEFYNNKRVIVNPLRIKNWIASELEARTVLYFTNITREAKDIEE 218 Query: 263 PLLTSI-DAISLECERVLGE----MGEAPAPEQYLVLEELIDMNQHHLNALG--VGHASL 315 + D SLE + + M EA + L +++ + + V + L Sbjct: 219 HKKGKLGDEKSLEAMHAIKQDAIKMKEALFRADFGTLAQILGKSWRSKKIISEIVSNDEL 278 Query: 316 DQLCQVTRARGLHS-KLTGAGGGGCGITLLKPGLEQPEVEATKQ 358 +++ ++ G +S K +GAG GG + P + ++A ++ Sbjct: 279 ERIYKLAIDNGAYSGKTSGAGAGGFMFFFVDPTKKYNLIKALRK 322 >5YYS-A nrPDB Length = 949 Score = 56.9 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 50/266 (18%), Positives = 98/266 (36%), Gaps = 18/266 (6%) Query: 86 EQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRA-LPSLDIVVWSELPPGAGLG 144 + +K+ +P A Y S+ + + +++ + + +P G+GLG Sbjct: 658 QDYKKIGSPFSIPKAALSLAGFAPAFSAVSYASLEEQLKDFGAGIEVTLLAAIPAGSGLG 717 Query: 145 SSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINK-WAFQGERMIHGNPSGV 203 +S+ + + A+ C + K+ C E L W Q ++ G Sbjct: 718 TSSILASTVLGAINDFCGLAWD--KNEICQRTLVLEQLLTTGGGWQDQYGGVLQGVKLLQ 775 Query: 204 DNAVSTWGGALRYHQGKISSLKRSPALQ--ILLTNTKVPRNTRALVAGVRNRLLKFPEIV 261 A +R+ L P + LL T + R + ++A + + + + Sbjct: 776 TEAGFAQSPLVRWLPDH---LFTHPEYKDCHLLYYTGITRTAKGILAEIVSSMFLNSSLH 832 Query: 262 APLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGH--ASLDQLC 319 LL+ + A +L +M EA ++ L+ AL G +++ + Sbjct: 833 LNLLSEMKAHAL-------DMNEAIQRGSFVEFGRLVGKTWEQNKALDSGTNPPAVEAII 885 Query: 320 QVTRARGLHSKLTGAGGGGCGITLLK 345 + + L KL GAGGGG + K Sbjct: 886 DLIKDYTLGYKLPGAGGGGYLYMVAK 911 >3K85-A nrPDB Length = 357 Score = 51.9 bits (122), Expect = 4e-07, Method: Composition-based stats. Identities = 55/353 (15%), Positives = 131/353 (37%), Gaps = 75/353 (21%) Query: 20 HAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAW-DVARLQSLDTSFLEQG 78 ++ ++G + L ++NL + ++ ++G+++++ + +++ +++L+ + L +G Sbjct: 24 YSDIYGGLILNATINLYAYCTIEETNSGRIEINAYDAQCCKSYLSMSQLEIDGEASLIKG 83 Query: 79 DVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALP-SLDIVVWSEL 137 +Y I R R P S I +++ Sbjct: 84 ------------------------------------VYNRIIRDYRLEPKSFKITTYNDA 107 Query: 138 PPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIH 197 P G+GLG+S+ VC+ A E + PL D ++ A++ ER Sbjct: 108 PAGSGLGTSSTMVVCILKA---FIEWLSLPLGD------------YETSRLAYEIERKDL 152 Query: 198 GNPSGV-DNAVSTWGGA--LRYHQGKI---------SSLKRSPALQILLTNTKVPRNTRA 245 G G D + +GG + + Q + + ++L T R++ A Sbjct: 153 GLSGGKQDQYAAAFGGFNYMEFLQNDLVIVNPLKMKRWIVDELESSMVLYFTGRSRSSAA 212 Query: 246 LVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHL 305 ++ + + + + I ++ + A ++ + Sbjct: 213 IINEQKKNTSEGNQTAIEAMHKIKQSAI-------DTKLALLKGDVGEFARILGEGWENK 265 Query: 306 NAL--GVGHASLDQLCQVTRARG-LHSKLTGAGGGGCGITLLKPGLEQPEVEA 355 + + + + + V G + K++GAGGGG + +++P ++ V A Sbjct: 266 KKMAGAITNPMIQEAFDVATGAGAMAGKVSGAGGGGFIMFVVEPTRKEEVVRA 318 >4UT4-A nrPDB Length = 346 Score = 51.9 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 49/264 (18%), Positives = 95/264 (35%), Gaps = 47/264 (17%) Query: 84 TSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGL 143 T +QVEK + ++ + + L + +Y ++ +L++ + + P G+GL Sbjct: 60 TDQQVEKHQLIS---EPLELNGTLNLHKAVYNHMIRNYNHGKPIALELSTFCDAPAGSGL 116 Query: 144 GSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSG- 202 GSS+ V + A E + PL D I + A++ ER+ G G Sbjct: 117 GSSSTLVVVMIKA---FVELLNLPLDDYA------------IAQLAYRIERVDCGLAGGR 161 Query: 203 VDNAVSTWGG---------------ALRYHQGKISSLKRSPALQILLTNTKVPRNTRALV 247 D +T+GG LR + L+ S ++L T V R + ++ Sbjct: 162 QDQYSATFGGFNFMEFYAAARTIVNPLRIKNWVLCELEAS----LVLFYTGVSRESAKII 217 Query: 248 AGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLN- 306 + ++ + I +L M EA + + + + Sbjct: 218 QDQSDNVVSHKTAAIEAMHGIKREALV-------MKEALLKGDFKAFVASMRLGWDNKKN 270 Query: 307 -ALGVGHASLDQLCQVTRARGLHS 329 A V +A +D++ G + Sbjct: 271 SARTVSNAHIDEIYDAAIRAGAQA 294 >3K17-A nrPDB Length = 365 Score = 48.0 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 61/337 (18%), Positives = 111/337 (32%), Gaps = 83/337 (24%) Query: 2 LSEVLLVSAPGKVILHGEHAVVH-GKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60 L L V PGK+ + GE+AVV G A+ ++N L L+ ++ + Sbjct: 3 LKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNELWI--------- 53 Query: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120 + V+ P +++ E + + + Sbjct: 54 -------------PHYENPVSWPIGGELKPDGEHWTFTAEAINIATTFLKS--------- 91 Query: 121 RKQRALPSLDIVVWSELPPGA----GLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNR 176 + L + +V+ +EL + GLGSSAA +V + AL+T Sbjct: 92 -EGIELTPVKMVIETELIDQSGAKYGLGSSAAATVAVINALMTKF--------------- 135 Query: 177 WTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQIL--- 233 + + + K A ++ GN S D A +GG + Y +K A + L Sbjct: 136 YPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEWVKHRLAYKSLEWF 195 Query: 234 ---------------------LTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAIS 272 + T P +T LV+ + + + LT Sbjct: 196 MKEPWPMLQIETLEEPVPTFSVGWTGTPVSTGKLVSQIHAFKQEDSKNYQHFLT------ 249 Query: 273 LECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALG 309 ++ ++ +A + +L I N+ L LG Sbjct: 250 -RNNEIMKQIIQAFHTKDEELLYSSIKENRRILQELG 285 >4P52-A nrPDB Length = 331 Score = 41.1 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 41/280 (14%), Positives = 92/280 (32%), Gaps = 32/280 (11%) Query: 57 GIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLY 116 + +DV + ++ ++ + G A +++ YL Sbjct: 37 NVSCGFDVLGFAVDNPGDEVLLRLSDKKGVRITSITGDDGRLPKDAEKNTVSISILRYLE 96 Query: 117 LSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNR 176 + ++I + ++P G+GLGSSAA +V A+ + Sbjct: 97 TLGIEQ-----GIEIELTKKMPLGSGLGSSAASTVAGVYAINQLLGN------------- 138 Query: 177 WTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTN 236 K +++ + +A +GE + G+ + A +GG + + + P + L Sbjct: 139 --KMEVKDLLPFAMEGEFLACGSAHADNVAPCLYGGFVLVRSYDPLDVVKLP-VPANLYA 195 Query: 237 TKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEE 296 T + + RN L K + + + +G + ++ Sbjct: 196 TIIHPHVEVQTKDARNILPKQIALSQAVAQWGN---------VGGLVAGLLMNDTSLIGR 246 Query: 297 LIDMNQHHLNALGVGHASLDQLCQVTRARG-LHSKLTGAG 335 + + A V D + + G L ++G+G Sbjct: 247 SM-QDHIVEPARSVLIPGFDDVKKAALDAGALGCSISGSG 285 >3GON-A nrPDB Length = 335 Score = 36.9 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 53/348 (15%), Positives = 112/348 (32%), Gaps = 55/348 (15%) Query: 5 VLLVSAPGKVILHGEHAVVH-GKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWD 63 ++ V GK+ GE+A++ G++AL + + + + ++ + + + + Sbjct: 1 MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPN 60 Query: 64 VARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQ 123 + + GD + + + + + + L + Sbjct: 61 PDY-SLIQETIALMGDFLAVRGQNLRPFSLAIYGKMEREGKKFGLGSSGSVVVLVVKALL 119 Query: 124 RALP-----SLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWT 178 +L + S + G S C+AA + + D V W Sbjct: 120 ALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIAA-----EDLVLYQSFDRQKVAAWL 174 Query: 179 KEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTK 238 +E+ A ER WG ++ S +K + L+ T Sbjct: 175 EEE-----NLATVLERD--------------WGFSI-------SQVKPTLECDFLVGWT- 207 Query: 239 VPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECER-VLGEMGEAPAPEQYLVLEEL 297 + +V + +I+ L + + + EA + + E Sbjct: 208 -------------KEVAVSSHMVQQIKQNINQNFLTSSKETVVSLVEALEQGKSEKIIEQ 254 Query: 298 IDMNQHHLNAL--GVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITL 343 +++ L L + L QL + ++ +K +GAGGG CGI L Sbjct: 255 VEVASKLLEGLSTDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIAL 302 >4RPF-A nrPDB Length = 310 Score = 36.1 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 22/51 (43%) Query: 129 LDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTK 179 + +V+ +P G+GLGSSA V A+ C + + + + Sbjct: 83 VAMVLEKNMPIGSGLGSSACSVVAGLMAMNEFCGQPLDKVTLLGMMGELEG 133 >3HUL-A nrPDB Length = 298 Score = 34.2 bits (76), Expect = 0.098, Method: Composition-based stats. Identities = 53/286 (18%), Positives = 92/286 (32%), Gaps = 51/286 (17%) Query: 79 DVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELP 138 D+ + G+P D + + L L ++ +V+ ++P Sbjct: 32 DIGAEADSWYIEHNIGGGIPHD---ETNVIIETALNLAPNLTPHH-------LVMTCDIP 81 Query: 139 PGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHG 198 P GLGSS+A V T+ E +KE+ I I G Sbjct: 82 PARGLGSSSAAVVAGIELANTLAEL------------NLSKEEKVRIA-------AEIEG 122 Query: 199 NPSGVDNAVS---TWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLL 255 +P V AV G L + L AL + ++ + GV L Sbjct: 123 HPDNVAPAVLGNWVVGAKLDGEDFYVRHLFPDCALIAFIPKAELLTSESR---GVLPDTL 179 Query: 256 KFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASL 315 F E V + M A + E+++ + H L Sbjct: 180 PFKEAVQ------------ASSIANVMIAAILRNDMTLAGEMMERDLWHEKYRSQLVPHL 227 Query: 316 DQLCQVTRARGLHSK-LTGAGGGGCGITLLKPGLEQPEVEATKQAL 360 Q+ V + +G ++ L+GAG + + P +++ + Q L Sbjct: 228 AQIRDVAKNQGAYAACLSGAGP---TVLVFAPRNLANKLQTSLQTL 270 >2V2V-A nrPDB Length = 271 Score = 33.0 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 52/162 (32%), Gaps = 23/162 (14%) Query: 129 LDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKW 188 I + +PPGAGLG ++ + + + + + + V + + Sbjct: 82 YSIFIQKNIPPGAGLGGGSSNLAVVLKKVNELLGSPLSEEELRELVGSISAD-------- 133 Query: 189 AFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVA 248 P + + G ++ + +I L +V +T + + Sbjct: 134 ----------APFFLLGKSAIGRGKGEVL----EPVETEISGKITLVIPQVSSSTGRVYS 179 Query: 249 GVRNRLLKFPEIVAP-LLTSIDAISLECERVLGEMGEAPAPE 289 +R PE + I E E VLG++ PE Sbjct: 180 SLREEHFVTPEYAEEKIQRIISGEVEEIENVLGDIARELYPE 221 >4JF0-A nrPDB Length = 422 Score = 29.2 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 28/79 (35%), Gaps = 6/79 (7%) Query: 2 LSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRA 61 +S +L G H +G LA ++ TF + L I KR Sbjct: 278 VSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGATFDIINTPE------VLQGIHTKRQ 331 Query: 62 WDVARLQSLDTSFLEQGDV 80 V LQ++D F D+ Sbjct: 332 QFVQHLQAIDEQFDIFSDI 350 >3UY5-A nrPDB Length = 428 Score = 28.4 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 15/29 (51%) Query: 327 LHSKLTGAGGGGCGITLLKPGLEQPEVEA 355 H+ G G GG + L++P + E EA Sbjct: 175 FHADAPGGGLGGSSVRLVRPTEHRGEFEA 203 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.110 0.255 Lambda K H 0.267 0.0339 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,615,912 Number of Sequences: 36641 Number of extensions: 427542 Number of successful extensions: 1284 Number of sequences better than 10.0: 36 Number of HSP's better than 10.0 without gapping: 45 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 1153 Number of HSP's gapped (non-prelim): 89 length of query: 396 length of database: 10,336,785 effective HSP length: 99 effective length of query: 297 effective length of database: 6,709,326 effective search space: 1992669822 effective search space used: 1992669822 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.6 bits)