BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q03048 (143 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1QPV-A nrPDB 293 2e-80 2I2Q-A nrPDB 180 2e-46 5IVU-A nrPDB 157 1e-39 1CNU-A nrPDB 140 2e-34 1F7S-A nrPDB 108 7e-25 5YU8-H nrPDB 103 2e-23 5L6W-C nrPDB 102 5e-23 2MV2-A nrPDB 99 5e-22 1AK7-A nrPDB 98 2e-21 2LJ8-A nrPDB 95 8e-21 2L72-A nrPDB 81 2e-16 2MOT-A nrPDB 80 3e-16 2MP4-A nrPDB 72 7e-14 2KVK-A nrPDB 67 3e-12 2LXX-A nrPDB 64 2e-11 2XFA-A nrPDB 62 1e-10 3Q2B-A nrPDB 59 9e-10 1M4J-A nrPDB 42 9e-05 2VAC-A nrPDB 41 1e-04 1HQZ-1 nrPDB 32 0.12 1V6F-A nrPDB 31 0.20 3L50-A nrPDB 29 0.89 2GHI-A nrPDB 28 1.3 5Y9P-A nrPDB 28 2.0 >1QPV-A nrPDB Length = 143 Score = 293 bits (750), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 143/143 (100%), Positives = 143/143 (100%) Query: 1 MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEN 60 MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEN Sbjct: 1 MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEN 60 Query: 61 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQ 120 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQ Sbjct: 61 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQ 120 Query: 121 GTDFSEVSYDSVLERVSRGAGSH 143 GTDFSEVSYDSVLERVSRGAGSH Sbjct: 121 GTDFSEVSYDSVLERVSRGAGSH 143 >2I2Q-A nrPDB Length = 137 Score = 180 bits (456), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 84/138 (60%), Positives = 108/138 (78%), Gaps = 2/138 (1%) Query: 1 MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEN 60 MS SGV V+ E L AF +LKLGK ++++F +ND KTEIVV++ STD +D FL LPE Sbjct: 1 MSFSGVKVSPECLEAFQELKLGKSLRYVVFKMNDTKTEIVVEKKSTDKDFDTFLGDLPEK 60 Query: 61 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQ 120 DC YAIYDFE+ N EG R+KI+F +WSPD AP++SKMVY+SSKD LRRA G+ TD+Q Sbjct: 61 DCRYAIYDFEF--NLGEGVRNKIIFISWSPDVAPIKSKMVYSSSKDTLRRAFTGIGTDIQ 118 Query: 121 GTDFSEVSYDSVLERVSR 138 TDFSEV+Y++VLE+V+R Sbjct: 119 ATDFSEVAYETVLEKVTR 136 >5IVU-A nrPDB Length = 141 Score = 157 bits (398), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 71/138 (51%), Positives = 100/138 (72%) Query: 2 SRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEND 61 S SGV + D + + LKLGKK K+I+F LN TEI V+++S YD FL LPE++ Sbjct: 3 SLSGVTLNDACVETYQQLKLGKKLKYIIFHLNKENTEIAVEKSSDSVDYDNFLADLPEDE 62 Query: 62 CLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQG 121 C +A+YD EYE GKR+K+ F +W+PD+A ++ KM YASSKD LRRAL G++ ++QG Sbjct: 63 CRWAVYDLEYEKEEGAGKRNKLTFVSWAPDSAKMKQKMAYASSKDILRRALTGIAVEIQG 122 Query: 122 TDFSEVSYDSVLERVSRG 139 TDFSEV++++VL++ SRG Sbjct: 123 TDFSEVAHENVLDKASRG 140 >1CNU-A nrPDB Length = 137 Score = 140 bits (353), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 59/136 (43%), Positives = 101/136 (74%), Gaps = 3/136 (2%) Query: 4 SGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETS-TDPSYDAFLEKLPENDC 62 SG+AV+D+ + FN+LKLG +++++ F +N + TE+VV+ + +Y+ F +LPE DC Sbjct: 1 SGIAVSDDCVQKFNELKLGHQHRYVTFKMNASNTEVVVEHVGGPNATYEDFKSQLPERDC 60 Query: 63 LYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGT 122 YAI+D+E++++G G+R+KI F W+PD+AP++SKM+Y S+KD++++ L G+ +VQ T Sbjct: 61 RYAIFDYEFQVDG--GQRNKITFILWAPDSAPIKSKMMYTSTKDSIKKKLVGIQVEVQAT 118 Query: 123 DFSEVSYDSVLERVSR 138 D +E+S D+V ER + Sbjct: 119 DAAEISEDAVSERAKK 134 >1F7S-A nrPDB Length = 139 Score = 108 bits (270), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 50/128 (39%), Positives = 82/128 (64%), Gaps = 2/128 (1%) Query: 4 SGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTD-PSYDAFLEKLPENDC 62 SG+AV D+ F +LK + ++FI++ + + + ++VV++ +Y+ F LP ++C Sbjct: 6 SGMAVHDDCKLRFLELKAKRTHRFIVYKIEEKQKQVVVEKVGQPIQTYEEFAACLPADEC 65 Query: 63 LYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGT 122 YAIYDF++ + ++SKI F W PD A VRSKM+YASSKD +R L+G+ ++Q T Sbjct: 66 RYAIYDFDF-VTAENCQKSKIFFIAWCPDIAKVRSKMIYASSKDRFKRELDGIQVELQAT 124 Query: 123 DFSEVSYD 130 D +E+ D Sbjct: 125 DPTEMDLD 132 >5YU8-H nrPDB Length = 166 Score = 103 bits (257), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 59/150 (39%), Positives = 86/150 (57%), Gaps = 23/150 (15%) Query: 4 SGVAVADESLTAFNDLK---------LGKKYKFILFGLNDAKTEIVVKE----------- 43 SGV V DE + FND+K + K+ K +LF L+D K +I+V+E Sbjct: 3 SGVTVNDEVIKVFNDMKVRKSSTPEEIKKRKKAVLFCLSDDKKQIIVEEAKQILVGDIGD 62 Query: 44 TSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYAS 103 T DP Y AF++ LP NDC YA+YD YE E K+ +VF W+P++AP++SKM+YAS Sbjct: 63 TVEDP-YTAFVKLLPLNDCRYALYDATYETK--ESKKEDLVFIFWAPESAPLKSKMIYAS 119 Query: 104 SKDALRRALNGVSTDVQGTDFSEVSYDSVL 133 SKDA+++ G+ + Q ++ S L Sbjct: 120 SKDAIKKKFTGIKHEWQVNGLDDIKDRSTL 149 >5L6W-C nrPDB Length = 167 Score = 102 bits (255), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 53/143 (37%), Positives = 84/143 (58%), Gaps = 21/143 (14%) Query: 4 SGVAVADESLTAFNDLKL---------GKKYKFILFGLNDAKTEIVVKE----------T 44 GVAV+D + FND+K+ K+ K +LF L++ K I+++E Sbjct: 4 CGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQ 63 Query: 45 STDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASS 104 + D Y F++ LP+ DC YA+YD YE E K+ +VF W+P++AP++SKM+YASS Sbjct: 64 TVDDPYATFVKMLPDKDCRYALYDATYETK--ESKKEDLVFIFWAPESAPLKSKMIYASS 121 Query: 105 KDALRRALNGVSTDVQGTDFSEV 127 KDA+++ L G+ ++Q + EV Sbjct: 122 KDAIKKKLTGIKHELQANCYEEV 144 >2MV2-A nrPDB Length = 148 Score = 99.4 bits (246), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 53/140 (37%), Positives = 82/140 (58%), Gaps = 7/140 (5%) Query: 4 SGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLE---KLPEN 60 SGV V+D T + ++K KK+++++F + D K V + YD FLE K Sbjct: 3 SGVTVSDVCKTTYEEIKKDKKHRYVIFYIRDEKQIDVETVADRNAEYDQFLEDIQKCGPG 62 Query: 61 DCLYAIYDFEY--EINGNE--GKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVS 116 +C Y ++DFEY + G K+ K+ +W PDTA V+ KM+Y+SS DAL+++L GV Sbjct: 63 ECRYGLFDFEYMHQCQGTSESSKKQKLFLMSWCPDTAKVKKKMLYSSSFDALKKSLVGVQ 122 Query: 117 TDVQGTDFSEVSYDSVLERV 136 +Q TD SE S ++V E++ Sbjct: 123 KYIQATDLSEASREAVEEKL 142 >1AK7-A nrPDB Length = 174 Score = 97.8 bits (242), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 54/155 (34%), Positives = 87/155 (56%), Gaps = 23/155 (14%) Query: 2 SRSGVAVADESLTAFNDLK---------LGKKYKFILFGLNDAKTEIVVKE--------- 43 S SGV VADE F D+K + K+ K ++F L+ K I+V+E Sbjct: 10 SASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV 69 Query: 44 --TSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVY 101 T TDP + F+ LPE DC YA+YD +E E ++ +++FF W+P+ AP++SKM+Y Sbjct: 70 GVTITDP-FKHFVGMLPEKDCRYALYDASFETK--ESRKEELMFFLWAPELAPLKSKMIY 126 Query: 102 ASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERV 136 ASSKDA+++ G+ + Q +++ + E++ Sbjct: 127 ASSKDAIKKKFQGIKHECQANGPEDLNRACIAEKL 161 >2LJ8-A nrPDB Length = 144 Score = 95.1 bits (235), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 51/132 (38%), Positives = 81/132 (61%), Gaps = 7/132 (5%) Query: 1 MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEN 60 M+ SGV+VADE +TA NDL+ KK ++++ + D K+ V ++D F+E + +N Sbjct: 9 MAMSGVSVADECVTALNDLR-HKKSRYVIMHIVDQKSIAVKTIGERGANFDQFIEAIDKN 67 Query: 61 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDA---LRRALNGV-S 116 YA +DFEY N +G R K++ +W+PD+ R+KM+Y+SS+DA L + G+ + Sbjct: 68 VPCYAAFDFEYTTN--DGPRDKLILISWNPDSGAPRTKMLYSSSRDALVPLTQGFQGIQA 125 Query: 117 TDVQGTDFSEVS 128 D G DF E+S Sbjct: 126 NDASGLDFEEIS 137 >2L72-A nrPDB Length = 139 Score = 80.9 bits (198), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 45/114 (39%), Positives = 63/114 (55%), Gaps = 13/114 (11%) Query: 4 SGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCL 63 SG+ V + + FN+LK+ K K+I+F + + K +V E + D F LP NDC Sbjct: 24 SGMGVDENCVARFNELKIRKTVKWIVFKIENTK---IVVEKDGKGNADEFRGALPANDCR 80 Query: 64 YAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVST 117 + +YD GN KI F W PD APV+ +M YASSKDAL + L+G + Sbjct: 81 FGVYDC-----GN-----KIQFVLWCPDNAPVKPRMTYASSKDALLKKLDGATA 124 >2MOT-A nrPDB Length = 118 Score = 80.5 bits (197), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 45/114 (39%), Positives = 63/114 (55%), Gaps = 13/114 (11%) Query: 4 SGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCL 63 SG+ V + + FN+LK+ K K+I+F + + K +V E + D F LP NDC Sbjct: 3 SGMGVDENCVARFNELKIRKTVKWIVFKIENTK---IVVEKDGKGNADEFRGALPANDCR 59 Query: 64 YAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVST 117 + +YD GN KI F W PD APV+ +M YASSKDAL + L+G + Sbjct: 60 FGVYDC-----GN-----KIQFVLWCPDNAPVKPRMTYASSKDALLKKLDGATA 103 >2MP4-A nrPDB Length = 165 Score = 72.4 bits (176), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 49/163 (30%), Positives = 81/163 (49%), Gaps = 23/163 (14%) Query: 4 SGVAVADESLTAFNDLKLGKK-YKFILFGLNDAKTEIVVKET-------------STDPS 49 SGV V + T+F L G+K Y++I+F +++ K + T S+ + Sbjct: 3 SGVMVDPDVQTSFQKLSEGRKEYRYIIFKIDENKVIVEAAVTQDQLGITGDDYDDSSKAA 62 Query: 50 YDAFLEKLPE-----NDCLYAIYDFEY---EINGNEGKRSKIVFFTWSPDTAPVRSKMVY 101 +D F+E + DC YA++DF++ + K KI+F PD A ++ KMVY Sbjct: 63 FDKFVEDVKSRTDNLTDCRYAVFDFKFTCSRVGAGTSKMDKIIFLQICPDGASIKKKMVY 122 Query: 102 ASSKDALRRAL-NGVSTDVQGTDFSEVSYDSVLERVSRGAGSH 143 ASS A++ +L G Q +D SE+S+ +L ++ G H Sbjct: 123 ASSAAAIKTSLGTGKILQFQVSDESEMSHKELLNKLGEKYGDH 165 >2KVK-A nrPDB Length = 144 Score = 66.6 bits (161), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 45/138 (32%), Positives = 70/138 (50%), Gaps = 7/138 (5%) Query: 1 MSRSGVAVADESLTAFNDLKLGK-KYKFILFGLNDAKTEIV-VKETSTDPSYDAFLEKLP 58 M+ SGV + + A +DL++ K +Y + G + K E+ V E S + Y EK Sbjct: 1 MAISGVTLEESVRGAIDDLRMKKSRYVMMCIGADGKKIEVTEVGERSVN--YTDLKEKFS 58 Query: 59 ENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTD 118 Y +DFEY G+ KR K++ W PDTA R KM+Y++S+DAL G Sbjct: 59 TEKPCYVAFDFEYNDAGS--KREKLILIQWIPDTARPREKMMYSASRDALSSVSEGY-LP 115 Query: 119 VQGTDFSEVSYDSVLERV 136 +Q D S + + ++ +V Sbjct: 116 IQANDESGLDAEEIIRKV 133 >2LXX-A nrPDB Length = 152 Score = 64.3 bits (155), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 45/140 (32%), Positives = 74/140 (52%), Gaps = 11/140 (7%) Query: 4 SGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKET-STDPSYDAFLEKLPE--- 59 SGV V A++ L ++ +I+F ++ T IVV++ + Y F+E++ + Sbjct: 3 SGVKVDPSCKNAYDLLHNKHQHSYIIFKIDKNDTAIVVEKVGEKNAPYAEFVEEMKKLVE 62 Query: 60 --NDCLYAIYDFEYEIN--GNEGKRS--KIVFFTWSPDTAPVRSKMVYASSKDALRRALN 113 +C YA D E + G EG + K++F + PD APVR +M+YASS AL+ +L Sbjct: 63 DGKECRYAAVDVEVTVQRQGAEGTSTLNKVIFVQYCPDNAPVRRRMLYASSVRALKASLG 122 Query: 114 GVST-DVQGTDFSEVSYDSV 132 S VQ ++ S++ SV Sbjct: 123 LESLFQVQASEMSDLDEKSV 142 >2XFA-A nrPDB Length = 148 Score = 61.6 bits (148), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 41/126 (32%), Positives = 65/126 (51%), Gaps = 9/126 (7%) Query: 4 SGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIV------VKETSTDPSYDAFLEKL 57 SGV V+DE + FN LK+ K+I++ + + + +V ++ TS D L Sbjct: 8 SGVNVSDECIYEFNRLKVKHLNKYIIYKIENLEKIVVDVLEHDMELTSLDNIIMRIKNNL 67 Query: 58 PENDCLYAIYDFEYEINGNEG-KRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVS 116 +C Y I D I EG R +I F WSP + + KM+YA+SK++L R +NG+ Sbjct: 68 KNTECRYIIADMP--IPTPEGVLRDRIYFIFWSPGLSKPKEKMLYAASKESLVRKINGIF 125 Query: 117 TDVQGT 122 ++ T Sbjct: 126 KSLEIT 131 >3Q2B-A nrPDB Length = 124 Score = 58.5 bits (140), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 15/116 (12%) Query: 4 SGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEND-- 61 SG+ V D +T FN++K+ K +I+F + + EI++ + ++ + +N+ Sbjct: 5 SGIRVNDNCVTEFNNMKIRKTCGWIIFVIQNC--EIIIHSKGASTTLTELVQSIDKNNEI 62 Query: 62 -CLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVS 116 C Y ++D SKI FF ++ +++ R +M YASSK A+ + + GV+ Sbjct: 63 QCAYVVFD----------AVSKIHFFMYARESSNSRDRMTYASSKQAILKKIEGVN 108 >1M4J-A nrPDB Length = 142 Score = 42.0 bits (97), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 33/135 (24%), Positives = 66/135 (48%), Gaps = 17/135 (12%) Query: 3 RSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPS------YDAF-LE 55 ++G+ +++ F + GK Y+ + + + E +V + + PS YD+F L Sbjct: 4 QTGIQASEDVKEIFARARNGK-YRLLKISIEN---EQLVVGSCSPPSDSWEQDYDSFVLP 59 Query: 56 KLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNG- 114 L + Y ++ ++ + + +F WSPD + VR KM+YA+++ L++ G Sbjct: 60 LLEDKQPCYVLF----RLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGG 115 Query: 115 -VSTDVQGTDFSEVS 128 + +V GT +VS Sbjct: 116 HIKDEVFGTVKEDVS 130 >2VAC-A nrPDB Length = 134 Score = 41.2 bits (95), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Query: 57 LPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNG 114 LP D Y Y ++ + + +F WSPD +PVR KM+YA+++ +++ G Sbjct: 55 LPLLDAQQPCY-LLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGG 111 >1HQZ-1 nrPDB Length = 141 Score = 31.6 bits (70), Expect = 0.12, Method: Compositional matrix adjust. Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 5/99 (5%) Query: 45 STDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASS 104 ST S+ FL+ E Y + ++ KI+ W PD+AP++++ +A++ Sbjct: 47 STGSSFHDFLQLFDETKVQYGLA----RVSPPGSDVEKIIIIGWCPDSAPLKTRASFAAN 102 Query: 105 KDALRRAL-NGVSTDVQGTDFSEVSYDSVLERVSRGAGS 142 A+ L G V D ++ + +L ++S AG+ Sbjct: 103 FAAVANNLFKGYHVQVTARDEDDLDENELLMKISNAAGA 141 >1V6F-A nrPDB Length = 151 Score = 30.8 bits (68), Expect = 0.20, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 3/82 (3%) Query: 28 ILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRS-KIVFF 86 I+ ++ + +V+ E S D ++LPE + +Y ++Y+ ++G+ S + F Sbjct: 38 IIMKIDKDERLVVLDEELEGVSPDELKDELPERQPRFIVYSYKYQ--HDDGRVSYPLCFI 95 Query: 87 TWSPDTAPVRSKMVYASSKDAL 108 SP +M+YA SK+ L Sbjct: 96 FSSPVGCKPEQQMMYAGSKNKL 117 >3L50-A nrPDB Length = 136 Score = 28.9 bits (63), Expect = 0.89, Method: Compositional matrix adjust. Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 3/82 (3%) Query: 28 ILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRS-KIVFF 86 I+ ++ + +V++E + S + +LPE + +Y ++Y ++G+ S + F Sbjct: 28 IIMKVDKDRQMVVLEEEFQNISPEELKMELPERQPRFVVYSYKY--VHDDGRVSYPLCFI 85 Query: 87 TWSPDTAPVRSKMVYASSKDAL 108 SP +M+YA SK+ L Sbjct: 86 FSSPVGCKPEQQMMYAGSKNRL 107 >2GHI-A nrPDB Length = 260 Score = 28.1 bits (61), Expect = 1.3, Method: Compositional matrix adjust. Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 5/57 (8%) Query: 3 RSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPE 59 RS + + + FN+ KY IL+G DA E V+K T + YD F+E LP+ Sbjct: 92 RSIIGIVPQDTILFNETI---KYN-ILYGKLDATDEEVIKATKSAQLYD-FIEALPK 143 >5Y9P-A nrPDB Length = 266 Score = 27.7 bits (60), Expect = 2.0, Method: Compositional matrix adjust. Identities = 16/67 (23%), Positives = 35/67 (52%), Gaps = 1/67 (1%) Query: 76 NEGKRSKIVFFTWSPDTAP-VRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLE 134 NE ++++ F + TA + +Y +++ A++RA++G+S ++ D+ L Sbjct: 123 NEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALP 182 Query: 135 RVSRGAG 141 +VS G Sbjct: 183 QVSLIKG 189 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1QPV-A nrPDB 202 5e-53 2I2Q-A nrPDB 181 1e-46 5IVU-A nrPDB 176 4e-45 1CNU-A nrPDB 167 1e-42 1F7S-A nrPDB 155 6e-39 1AK7-A nrPDB 145 6e-36 2MV2-A nrPDB 144 9e-36 2LJ8-A nrPDB 144 1e-35 5YU8-H nrPDB 139 5e-34 5L6W-C nrPDB 135 7e-33 2MP4-A nrPDB 132 5e-32 2L72-A nrPDB 130 2e-31 2MOT-A nrPDB 130 3e-31 2LXX-A nrPDB 129 4e-31 2XFA-A nrPDB 125 5e-30 2KVK-A nrPDB 125 6e-30 1M4J-A nrPDB 110 1e-25 3Q2B-A nrPDB 104 2e-23 2VAC-A nrPDB 91 1e-19 Sequences not found previously or not previously below threshold: 1V6F-A nrPDB 66 4e-12 3L50-A nrPDB 61 2e-10 4JD2-H nrPDB 60 4e-10 1HQZ-1 nrPDB 57 4e-09 5YNR-A nrPDB 55 1e-08 2W0I-A nrPDB 44 3e-05 4LIZ-A nrPDB 43 4e-05 2D8B-A nrPDB 39 7e-04 3DAW-B nrPDB 39 8e-04 2HD7-A nrPDB 38 0.001 2WAN-A nrPDB 30 0.24 3O47-A nrPDB 30 0.51 5Y1Z-A nrPDB 30 0.51 5V8F-9 nrPDB 29 0.76 3AIC-A nrPDB 27 2.4 5B5R-A nrPDB 27 2.5 1ZOV-A nrPDB 27 3.0 4FFM-A nrPDB 27 4.0 3ICE-A nrPDB 26 7.4 >1QPV-A nrPDB Length = 143 Score = 202 bits (513), Expect = 5e-53, Method: Composition-based stats. Identities = 143/143 (100%), Positives = 143/143 (100%) Query: 1 MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEN 60 MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEN Sbjct: 1 MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEN 60 Query: 61 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQ 120 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQ Sbjct: 61 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQ 120 Query: 121 GTDFSEVSYDSVLERVSRGAGSH 143 GTDFSEVSYDSVLERVSRGAGSH Sbjct: 121 GTDFSEVSYDSVLERVSRGAGSH 143 >2I2Q-A nrPDB Length = 137 Score = 181 bits (459), Expect = 1e-46, Method: Composition-based stats. Identities = 83/139 (59%), Positives = 108/139 (77%), Gaps = 2/139 (1%) Query: 1 MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEN 60 MS SGV V+ E L AF +LKLGK ++++F +ND KTEIVV++ STD +D FL LPE Sbjct: 1 MSFSGVKVSPECLEAFQELKLGKSLRYVVFKMNDTKTEIVVEKKSTDKDFDTFLGDLPEK 60 Query: 61 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQ 120 DC YAIYDFE+ + EG R+KI+F +WSPD AP++SKMVY+SSKD LRRA G+ TD+Q Sbjct: 61 DCRYAIYDFEFNL--GEGVRNKIIFISWSPDVAPIKSKMVYSSSKDTLRRAFTGIGTDIQ 118 Query: 121 GTDFSEVSYDSVLERVSRG 139 TDFSEV+Y++VLE+V+R Sbjct: 119 ATDFSEVAYETVLEKVTRK 137 >5IVU-A nrPDB Length = 141 Score = 176 bits (445), Expect = 4e-45, Method: Composition-based stats. Identities = 71/139 (51%), Positives = 100/139 (71%) Query: 2 SRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEND 61 S SGV + D + + LKLGKK K+I+F LN TEI V+++S YD FL LPE++ Sbjct: 3 SLSGVTLNDACVETYQQLKLGKKLKYIIFHLNKENTEIAVEKSSDSVDYDNFLADLPEDE 62 Query: 62 CLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQG 121 C +A+YD EYE GKR+K+ F +W+PD+A ++ KM YASSKD LRRAL G++ ++QG Sbjct: 63 CRWAVYDLEYEKEEGAGKRNKLTFVSWAPDSAKMKQKMAYASSKDILRRALTGIAVEIQG 122 Query: 122 TDFSEVSYDSVLERVSRGA 140 TDFSEV++++VL++ SRG Sbjct: 123 TDFSEVAHENVLDKASRGH 141 >1CNU-A nrPDB Length = 137 Score = 167 bits (423), Expect = 1e-42, Method: Composition-based stats. Identities = 59/136 (43%), Positives = 101/136 (74%), Gaps = 3/136 (2%) Query: 4 SGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETS-TDPSYDAFLEKLPENDC 62 SG+AV+D+ + FN+LKLG +++++ F +N + TE+VV+ + +Y+ F +LPE DC Sbjct: 1 SGIAVSDDCVQKFNELKLGHQHRYVTFKMNASNTEVVVEHVGGPNATYEDFKSQLPERDC 60 Query: 63 LYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGT 122 YAI+D+E++++G G+R+KI F W+PD+AP++SKM+Y S+KD++++ L G+ +VQ T Sbjct: 61 RYAIFDYEFQVDG--GQRNKITFILWAPDSAPIKSKMMYTSTKDSIKKKLVGIQVEVQAT 118 Query: 123 DFSEVSYDSVLERVSR 138 D +E+S D+V ER + Sbjct: 119 DAAEISEDAVSERAKK 134 >1F7S-A nrPDB Length = 139 Score = 155 bits (392), Expect = 6e-39, Method: Composition-based stats. Identities = 51/137 (37%), Positives = 85/137 (62%), Gaps = 2/137 (1%) Query: 2 SRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTD-PSYDAFLEKLPEN 60 + SG+AV D+ F +LK + ++FI++ + + + ++VV++ +Y+ F LP + Sbjct: 4 AASGMAVHDDCKLRFLELKAKRTHRFIVYKIEEKQKQVVVEKVGQPIQTYEEFAACLPAD 63 Query: 61 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQ 120 +C YAIYDF++ + ++SKI F W PD A VRSKM+YASSKD +R L+G+ ++Q Sbjct: 64 ECRYAIYDFDF-VTAENCQKSKIFFIAWCPDIAKVRSKMIYASSKDRFKRELDGIQVELQ 122 Query: 121 GTDFSEVSYDSVLERVS 137 TD +E+ D R + Sbjct: 123 ATDPTEMDLDVFRSRAN 139 >1AK7-A nrPDB Length = 174 Score = 145 bits (366), Expect = 6e-36, Method: Composition-based stats. Identities = 50/155 (32%), Positives = 84/155 (54%), Gaps = 21/155 (13%) Query: 2 SRSGVAVADESLTAFNDLK---------LGKKYKFILFGLNDAKTEIVVKE--------- 43 S SGV VADE F D+K + K+ K ++F L+ K I+V+E Sbjct: 10 SASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV 69 Query: 44 -TSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYA 102 + + F+ LPE DC YA+YD +E E ++ +++FF W+P+ AP++SKM+YA Sbjct: 70 GVTITDPFKHFVGMLPEKDCRYALYDASFETK--ESRKEELMFFLWAPELAPLKSKMIYA 127 Query: 103 SSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVS 137 SSKDA+++ G+ + Q +++ + E++ Sbjct: 128 SSKDAIKKKFQGIKHECQANGPEDLNRACIAEKLG 162 >2MV2-A nrPDB Length = 148 Score = 144 bits (364), Expect = 9e-36, Method: Composition-based stats. Identities = 51/141 (36%), Positives = 82/141 (58%), Gaps = 7/141 (4%) Query: 3 RSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPE--- 59 SGV V+D T + ++K KK+++++F + D K V + YD FLE + + Sbjct: 2 ASGVTVSDVCKTTYEEIKKDKKHRYVIFYIRDEKQIDVETVADRNAEYDQFLEDIQKCGP 61 Query: 60 NDCLYAIYDFEY----EINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGV 115 +C Y ++DFEY + K+ K+ +W PDTA V+ KM+Y+SS DAL+++L GV Sbjct: 62 GECRYGLFDFEYMHQCQGTSESSKKQKLFLMSWCPDTAKVKKKMLYSSSFDALKKSLVGV 121 Query: 116 STDVQGTDFSEVSYDSVLERV 136 +Q TD SE S ++V E++ Sbjct: 122 QKYIQATDLSEASREAVEEKL 142 >2LJ8-A nrPDB Length = 144 Score = 144 bits (364), Expect = 1e-35, Method: Composition-based stats. Identities = 49/137 (35%), Positives = 81/137 (59%), Gaps = 4/137 (2%) Query: 1 MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEN 60 M+ SGV+VADE +TA NDL+ KK ++++ + D K+ V ++D F+E + +N Sbjct: 9 MAMSGVSVADECVTALNDLR-HKKSRYVIMHIVDQKSIAVKTIGERGANFDQFIEAIDKN 67 Query: 61 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQ 120 YA +DFEY N +G R K++ +W+PD+ R+KM+Y+SS+DAL G +Q Sbjct: 68 VPCYAAFDFEYTTN--DGPRDKLILISWNPDSGAPRTKMLYSSSRDALVPLTQGFQG-IQ 124 Query: 121 GTDFSEVSYDSVLERVS 137 D S + ++ + +V Sbjct: 125 ANDASGLDFEEISRKVK 141 >5YU8-H nrPDB Length = 166 Score = 139 bits (349), Expect = 5e-34, Method: Composition-based stats. Identities = 57/155 (36%), Positives = 88/155 (56%), Gaps = 22/155 (14%) Query: 3 RSGVAVADESLTAFNDLK---------LGKKYKFILFGLNDAKTEIVVKET--------- 44 SGV V DE + FND+K + K+ K +LF L+D K +I+V+E Sbjct: 2 ASGVTVNDEVIKVFNDMKVRKSSTPEEIKKRKKAVLFCLSDDKKQIIVEEAKQILVGDIG 61 Query: 45 -STDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYAS 103 + + Y AF++ LP NDC YA+YD YE E K+ +VF W+P++AP++SKM+YAS Sbjct: 62 DTVEDPYTAFVKLLPLNDCRYALYDATYETK--ESKKEDLVFIFWAPESAPLKSKMIYAS 119 Query: 104 SKDALRRALNGVSTDVQGTDFSEVSYDSVL-ERVS 137 SKDA+++ G+ + Q ++ S L E++ Sbjct: 120 SKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLG 154 >5L6W-C nrPDB Length = 167 Score = 135 bits (339), Expect = 7e-33, Method: Composition-based stats. Identities = 55/155 (35%), Positives = 88/155 (56%), Gaps = 22/155 (14%) Query: 3 RSGVAVADESLTAFNDLKL---------GKKYKFILFGLNDAKTEIVVKE---------- 43 GVAV+D + FND+K+ K+ K +LF L++ K I+++E Sbjct: 3 ACGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVG 62 Query: 44 TSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYAS 103 + D Y F++ LP+ DC YA+YD YE E K+ +VF W+P++AP++SKM+YAS Sbjct: 63 QTVDDPYATFVKMLPDKDCRYALYDATYETK--ESKKEDLVFIFWAPESAPLKSKMIYAS 120 Query: 104 SKDALRRALNGVSTDVQGTDFSEVSYDSVL-ERVS 137 SKDA+++ L G+ ++Q + EV L E++ Sbjct: 121 SKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLG 155 >2MP4-A nrPDB Length = 165 Score = 132 bits (332), Expect = 5e-32, Method: Composition-based stats. Identities = 49/163 (30%), Positives = 81/163 (49%), Gaps = 23/163 (14%) Query: 4 SGVAVADESLTAFNDLKLGKK-YKFILFGLNDAKTEIVVKET-------------STDPS 49 SGV V + T+F L G+K Y++I+F +++ K + T S+ + Sbjct: 3 SGVMVDPDVQTSFQKLSEGRKEYRYIIFKIDENKVIVEAAVTQDQLGITGDDYDDSSKAA 62 Query: 50 YDAFLEKLPE-----NDCLYAIYDFEY---EINGNEGKRSKIVFFTWSPDTAPVRSKMVY 101 +D F+E + DC YA++DF++ + K KI+F PD A ++ KMVY Sbjct: 63 FDKFVEDVKSRTDNLTDCRYAVFDFKFTCSRVGAGTSKMDKIIFLQICPDGASIKKKMVY 122 Query: 102 ASSKDALRRALN-GVSTDVQGTDFSEVSYDSVLERVSRGAGSH 143 ASS A++ +L G Q +D SE+S+ +L ++ G H Sbjct: 123 ASSAAAIKTSLGTGKILQFQVSDESEMSHKELLNKLGEKYGDH 165 >2L72-A nrPDB Length = 139 Score = 130 bits (327), Expect = 2e-31, Method: Composition-based stats. Identities = 43/127 (33%), Positives = 68/127 (53%), Gaps = 14/127 (11%) Query: 3 RSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDC 62 SG+ V + + FN+LK+ K K+I+F + + K +V E + D F LP NDC Sbjct: 23 ASGMGVDENCVARFNELKIRKTVKWIVFKIENTK---IVVEKDGKGNADEFRGALPANDC 79 Query: 63 LYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGV-STDVQG 121 + +YD +KI F W PD APV+ +M YASSKDAL + L+G + ++ Sbjct: 80 RFGVYDC----------GNKIQFVLWCPDNAPVKPRMTYASSKDALLKKLDGATAVALEA 129 Query: 122 TDFSEVS 128 + +++ Sbjct: 130 HEMGDLA 136 >2MOT-A nrPDB Length = 118 Score = 130 bits (326), Expect = 3e-31, Method: Composition-based stats. Identities = 43/127 (33%), Positives = 68/127 (53%), Gaps = 14/127 (11%) Query: 3 RSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDC 62 SG+ V + + FN+LK+ K K+I+F + + K +V E + D F LP NDC Sbjct: 2 ASGMGVDENCVARFNELKIRKTVKWIVFKIENTK---IVVEKDGKGNADEFRGALPANDC 58 Query: 63 LYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGV-STDVQG 121 + +YD +KI F W PD APV+ +M YASSKDAL + L+G + ++ Sbjct: 59 RFGVYDC----------GNKIQFVLWCPDNAPVKPRMTYASSKDALLKKLDGATAVALEA 108 Query: 122 TDFSEVS 128 + +++ Sbjct: 109 HEMGDLA 115 >2LXX-A nrPDB Length = 152 Score = 129 bits (325), Expect = 4e-31, Method: Composition-based stats. Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 11/141 (7%) Query: 3 RSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETS-TDPSYDAFLEKLPE-- 59 SGV V A++ L ++ +I+F ++ T IVV++ + Y F+E++ + Sbjct: 2 ASGVKVDPSCKNAYDLLHNKHQHSYIIFKIDKNDTAIVVEKVGEKNAPYAEFVEEMKKLV 61 Query: 60 ---NDCLYAIYDFEYEIN----GNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRAL 112 +C YA D E + +K++F + PD APVR +M+YASS AL+ +L Sbjct: 62 EDGKECRYAAVDVEVTVQRQGAEGTSTLNKVIFVQYCPDNAPVRRRMLYASSVRALKASL 121 Query: 113 NGVST-DVQGTDFSEVSYDSV 132 S VQ ++ S++ SV Sbjct: 122 GLESLFQVQASEMSDLDEKSV 142 >2XFA-A nrPDB Length = 148 Score = 125 bits (315), Expect = 5e-30, Method: Composition-based stats. Identities = 40/135 (29%), Positives = 66/135 (48%), Gaps = 8/135 (5%) Query: 3 RSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIV------VKETSTDPSYDAFLEK 56 SGV V+DE + FN LK+ K+I++ + + + +V ++ TS D Sbjct: 7 VSGVNVSDECIYEFNRLKVKHLNKYIIYKIENLEKIVVDVLEHDMELTSLDNIIMRIKNN 66 Query: 57 LPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVS 116 L +C Y I D R +I F WSP + + KM+YA+SK++L R +NG+ Sbjct: 67 LKNTECRYIIADMPIPTPEGV-LRDRIYFIFWSPGLSKPKEKMLYAASKESLVRKINGIF 125 Query: 117 TDVQGT-DFSEVSYD 130 ++ T D +E + Sbjct: 126 KSLEITCDINEFEEE 140 >2KVK-A nrPDB Length = 144 Score = 125 bits (314), Expect = 6e-30, Method: Composition-based stats. Identities = 41/137 (29%), Positives = 67/137 (48%), Gaps = 5/137 (3%) Query: 1 MSRSGVAVADESLTAFNDLKLGKKYKFILFGL-NDAKTEIVVKETSTDPSYDAFLEKLPE 59 M+ SGV + + A +DL++ K ++++ + D K V + +Y EK Sbjct: 1 MAISGVTLEESVRGAIDDLRMKKS-RYVMMCIGADGKKIEVTEVGERSVNYTDLKEKFST 59 Query: 60 NDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDV 119 Y +DFEY G KR K++ W PDTA R KM+Y++S+DAL G + Sbjct: 60 EKPCYVAFDFEYNDAG--SKREKLILIQWIPDTARPREKMMYSASRDALSSVSEGY-LPI 116 Query: 120 QGTDFSEVSYDSVLERV 136 Q D S + + ++ +V Sbjct: 117 QANDESGLDAEEIIRKV 133 >1M4J-A nrPDB Length = 142 Score = 110 bits (276), Expect = 1e-25, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 65/135 (48%), Gaps = 17/135 (12%) Query: 3 RSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDP------SYDAFL-E 55 ++G+ +++ F + GK Y+ + + + E +V + + P YD+F+ Sbjct: 4 QTGIQASEDVKEIFARARNGK-YRLLKISIEN---EQLVVGSCSPPSDSWEQDYDSFVLP 59 Query: 56 KLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNG- 114 L + Y ++ ++ + + +F WSPD + VR KM+YA+++ L++ G Sbjct: 60 LLEDKQPCYVLF----RLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGG 115 Query: 115 -VSTDVQGTDFSEVS 128 + +V GT +VS Sbjct: 116 HIKDEVFGTVKEDVS 130 >3Q2B-A nrPDB Length = 124 Score = 104 bits (258), Expect = 2e-23, Method: Composition-based stats. Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 15/118 (12%) Query: 3 RSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPEND- 61 SG+ V D +T FN++K+ K +I+F + + EI++ + ++ + +N+ Sbjct: 4 ISGIRVNDNCVTEFNNMKIRKTCGWIIFVIQNC--EIIIHSKGASTTLTELVQSIDKNNE 61 Query: 62 --CLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVST 117 C Y ++D SKI FF ++ +++ R +M YASSK A+ + + GV+ Sbjct: 62 IQCAYVVFDA----------VSKIHFFMYARESSNSRDRMTYASSKQAILKKIEGVNV 109 >2VAC-A nrPDB Length = 134 Score = 91.3 bits (225), Expect = 1e-19, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 56/130 (43%), Gaps = 11/130 (8%) Query: 5 GVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETST---DPSYDA-FLEKLPEN 60 G+ +E F + G + I + D + + + D YD L L Sbjct: 3 GIHATEELKEFFAKARAG-SVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPLLDAQ 61 Query: 61 DCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNG--VSTD 118 Y +Y ++ + + +F WSPD +PVR KM+YA+++ +++ G + + Sbjct: 62 QPCYLLY----RLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDE 117 Query: 119 VQGTDFSEVS 128 + GT ++S Sbjct: 118 LFGTVKDDLS 127 >1V6F-A nrPDB Length = 151 Score = 66.3 bits (160), Expect = 4e-12, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 58/137 (42%), Gaps = 4/137 (2%) Query: 8 VADESLTAFNDLKLGKK--YKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYA 65 VA++ + + K+ I+ ++ + +V+ E S D ++LPE + Sbjct: 16 VAEDLVEKLRKFRFRKETHNAAIIMKIDKDERLVVLDEELEGVSPDELKDELPERQPRFI 75 Query: 66 IYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFS 125 +Y ++Y+ + + F SP +M+YA SK+ L + + + Sbjct: 76 VYSYKYQHDDGR-VSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKV-FEIRNTE 133 Query: 126 EVSYDSVLERVSRGAGS 142 +++ + + E++ G S Sbjct: 134 DLTEEWLREKLGSGPSS 150 >3L50-A nrPDB Length = 136 Score = 60.5 bits (145), Expect = 2e-10, Method: Composition-based stats. Identities = 25/133 (18%), Positives = 56/133 (42%), Gaps = 6/133 (4%) Query: 8 VADESLTAFNDLKLGKK--YKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYA 65 V E + K+ I+ ++ + +V++E + S + +LPE + Sbjct: 6 VDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKMELPERQPRFV 65 Query: 66 IYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVST-DVQGTDF 124 +Y ++Y + + F SP +M+YA SK+ L + +++ TD Sbjct: 66 VYSYKYVHDDGR-VSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRTTD- 123 Query: 125 SEVSYDSVLERVS 137 +++ + E++S Sbjct: 124 -DLTEAWLQEKLS 135 >4JD2-H nrPDB Length = 142 Score = 59.7 bits (143), Expect = 4e-10, Method: Composition-based stats. Identities = 23/133 (17%), Positives = 56/133 (42%), Gaps = 6/133 (4%) Query: 8 VADESLTAFNDLKLGKK--YKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYA 65 V E + K+ I+ ++ + +V+++ + S + +LPE + Sbjct: 10 VDPELKETLRKFRFRKETNNAAIIMKVDKDRQMVVLEDELQNISPEELKLELPERQPRFV 69 Query: 66 IYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVST-DVQGTDF 124 +Y ++Y + + F SP +M+YA SK+ L + +++ TD Sbjct: 70 VYSYKYVHDDGR-VSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRTTD- 127 Query: 125 SEVSYDSVLERVS 137 +++ + E+++ Sbjct: 128 -DLTETWLKEKLA 139 >1HQZ-1 nrPDB Length = 141 Score = 56.7 bits (135), Expect = 4e-09, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 50/116 (43%), Gaps = 8/116 (6%) Query: 27 FILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFF 86 +++ N K + ST S+ FL+ E Y + ++ KI+ Sbjct: 32 WLIISPNAKKE---YEPESTGSSFHDFLQLFDETKVQYGLA----RVSPPGSDVEKIIII 84 Query: 87 TWSPDTAPVRSKMVYASSKDALRRA-LNGVSTDVQGTDFSEVSYDSVLERVSRGAG 141 W PD+AP++++ +A++ A+ G V D ++ + +L ++S AG Sbjct: 85 GWCPDSAPLKTRASFAANFAAVANNLFKGYHVQVTARDEDDLDENELLMKISNAAG 140 >5YNR-A nrPDB Length = 140 Score = 54.7 bits (130), Expect = 1e-08, Method: Composition-based stats. Identities = 19/131 (14%), Positives = 54/131 (41%), Gaps = 4/131 (3%) Query: 7 AVADESLTAFNDLKLGK--KYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLY 64 ++ D + K ++ ++ E+ ++ D S + F E+LP + Sbjct: 11 SIPDGVKEDLKKFRFSKSTTMNALILKIDRESHELQSEQLLNDCSIEEFKEELPSQQPRF 70 Query: 65 AIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDF 124 + + + + +E ++ + P+ + +M+YA S++ + + VS + + D Sbjct: 71 ILLSW-CKKHSDERISYPMLLIYYCPNGSSPELQMLYAGSRNFIVNECH-VSKNTEIRDI 128 Query: 125 SEVSYDSVLER 135 E+ + + + Sbjct: 129 DEIDDELLESK 139 >2W0I-A nrPDB Length = 135 Score = 43.9 bits (102), Expect = 3e-05, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 56/137 (40%), Gaps = 10/137 (7%) Query: 6 VAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYA 65 + + E+ A LK K +I L+ + I + T ++P + Y Sbjct: 2 MPLQPEAQRALQQLK-QKMVNYIQMKLDLERETIELVHTE-PTDVAQLPSRVPRDAARYH 59 Query: 66 IYDFEYEINGNEGKRSKIVFFTWSPD-TAPVRSKMVYASSKDALRRALNG-----VSTDV 119 + +++ G+ +VF P ++ +M+Y+S K L ++ ++ + Sbjct: 60 FFLYKHTHEGD--PLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKI 117 Query: 120 QGTDFSEVSYDSVLERV 136 + D +E++ + + + V Sbjct: 118 EIGDGAELTAEFLDDEV 134 >4LIZ-A nrPDB Length = 142 Score = 43.2 bits (100), Expect = 4e-05, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 47/118 (39%), Gaps = 4/118 (3%) Query: 27 FILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFF 86 F++FG+ ++VV + L E+ +A Y E KR K VF Sbjct: 26 FVVFGVQTQPNKLVVDAKGKGG-LEEVKAALKEDALQFAYY--RTISGDEESKRVKFVFI 82 Query: 87 TWSPDT-APVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRGAGSH 143 +W+ + + + V + K ++ +N ++ T ++ D + ++ +H Sbjct: 83 SWAGEGIKKPKLRAVMSILKGDVKNVINNFHIELHATSLDDLVEDEIAAKIKLEHHAH 140 >2D8B-A nrPDB Length = 166 Score = 38.9 bits (89), Expect = 7e-04, Method: Composition-based stats. Identities = 27/149 (18%), Positives = 63/149 (42%), Gaps = 12/149 (8%) Query: 2 SRSGVA--VADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPE 59 + GVA ++ ++ A L K+ ++ ++ I++ T + +++P+ Sbjct: 21 TLQGVAFPISRDAFQALEKLS-KKQLNYVQLEIDIKNETIILANTE-NTELRDLPKRIPK 78 Query: 60 NDCLYAIYDFEYEINGNEGKRSKIVFFTWSPD-TAPVRSKMVYASSKDALRRALN----- 113 + Y + +++ G+ +VF P T +R +M+Y+S K L + Sbjct: 79 DSARYHFFLYKHSHEGDY--LESVVFIYSMPGYTCSIRERMLYSSCKSPLLEIVERQLQM 136 Query: 114 GVSTDVQGTDFSEVSYDSVLERVSRGAGS 142 V ++ + E++ D + + V G S Sbjct: 137 DVIRKIEIDNGDELTADFLYDEVHSGPSS 165 >3DAW-B nrPDB Length = 164 Score = 38.9 bits (89), Expect = 8e-04, Method: Composition-based stats. Identities = 26/150 (17%), Positives = 63/150 (42%), Gaps = 12/150 (8%) Query: 2 SRSGVA--VADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPE 59 + GVA ++ ++ A L K+ ++ ++ I++ T + +++P+ Sbjct: 16 TLQGVAFPISRDAFQALEKLS-KKQLNYVQLEIDIKNETIILANTE-NTELRDLPKRIPK 73 Query: 60 NDCLYAIYDFEYEINGNEGKRSKIVFFTWSPD-TAPVRSKMVYASSKDALRRALN----- 113 + Y + +++ G+ +VF P T +R +M+Y+S K L + Sbjct: 74 DSARYHFFLYKHSHEGDY--LESVVFIYSMPGYTCSIRERMLYSSCKSPLLEIVERQLQM 131 Query: 114 GVSTDVQGTDFSEVSYDSVLERVSRGAGSH 143 V ++ + E++ D + + V +H Sbjct: 132 DVIRKIEIDNGDELTADFLYDEVHPKQHAH 161 >2HD7-A nrPDB Length = 142 Score = 38.2 bits (87), Expect = 0.001, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 8 VADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIY 67 ++ ++ A L K+ ++ ++ I++ T + +++P++ Y + Sbjct: 8 ISRDAFQALEKLS-KKQLNYVQLEIDIKNETIILANTE-NTELRDLPKRIPKDSARYHFF 65 Query: 68 DFEYEINGNEGKRSKIVFFTWSPD-TAPVRSKMVYASSKDALR 109 +++ G+ +VF P T +R +M+Y+S K L Sbjct: 66 LYKHSHEGDY--LESVVFIYSMPGYTCSIRERMLYSSCKSPLL 106 >2WAN-A nrPDB Length = 921 Score = 30.5 bits (67), Expect = 0.24, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 25/57 (43%), Gaps = 1/57 (1%) Query: 57 LPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALN 113 LP N YD+ GN + F W+P + V+ ++Y S K ++ + L Sbjct: 301 LPRNVLNLPRYDYSGNDLGNVYSKDATSFRVWAPTASNVQL-LLYNSEKGSITKQLE 356 >3O47-A nrPDB Length = 329 Score = 29.7 bits (65), Expect = 0.51, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 26/64 (40%), Gaps = 5/64 (7%) Query: 35 AKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFT----WSP 90 E+ + + + FLE + D +++ + +Y R K+V WS Sbjct: 86 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQE-KYNSRAAALFRDKVVALAEGREWSL 144 Query: 91 DTAP 94 +++P Sbjct: 145 ESSP 148 >5Y1Z-A nrPDB Length = 137 Score = 29.7 bits (65), Expect = 0.51, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 24/65 (36%) Query: 73 INGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSV 132 + ++ K V W + P K AS + GV V + ++ ++ Sbjct: 72 VKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAI 131 Query: 133 LERVS 137 +R+S Sbjct: 132 GQRLS 136 >5V8F-9 nrPDB Length = 513 Score = 28.9 bits (63), Expect = 0.76, Method: Composition-based stats. Identities = 15/96 (15%), Positives = 38/96 (39%), Gaps = 6/96 (6%) Query: 54 LEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVR----SKMVYASSKDALR 109 + P ++D KR K+ F +P+++P + S+ ++ +K L+ Sbjct: 4 IPITPTKRIRRNLFDDAPATPPRPLKRKKLQFTDVTPESSPEKLQFGSQSIFLRTKALLQ 63 Query: 110 RALNGVSTDVQ--GTDFSEVSYDSVLERVSRGAGSH 143 ++ V+ + Y+ V+ +++ H Sbjct: 64 KSSELVNLNSSDGALPARTAEYEQVMNFLAKAISEH 99 >3AIC-A nrPDB Length = 844 Score = 27.4 bits (59), Expect = 2.4, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 32/76 (42%), Gaps = 1/76 (1%) Query: 62 CLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQG 121 Y + D + E K + + TW PD R + Y +++ + + N ++ +Q Sbjct: 31 PKYILKDGKTWTQSTE-KDFRPLLMTWWPDQETQRQYVNYMNAQLGIHQTYNTATSPLQL 89 Query: 122 TDFSEVSYDSVLERVS 137 ++ + E+++ Sbjct: 90 NLAAQTIQTKIEEKIT 105 >5B5R-A nrPDB Length = 468 Score = 27.4 bits (59), Expect = 2.5, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 18/30 (60%) Query: 16 FNDLKLGKKYKFILFGLNDAKTEIVVKETS 45 N+++ +K +++ +AK E+ V++T Sbjct: 145 LNEMRYHEKNLYVVMEAVEAKQEVTVEQTG 174 >1ZOV-A nrPDB Length = 386 Score = 27.0 bits (58), Expect = 3.0, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Query: 4 SGVAVADESLTAFNDLKLGKKYKFILFGLNDA--KTEIVVKETSTDPSYDA 52 SGV ++ + A+ +L + + + TE +V + SY A Sbjct: 144 SGVLFSENCIQAYRELAEAHGATVLTYTPVEDFEVTEDLVTIKTAKGSYTA 194 >4FFM-A nrPDB Length = 363 Score = 26.6 bits (57), Expect = 4.0, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 22/54 (40%) Query: 32 LNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVF 85 L +K V + + + FL + E ++DFE + K+SK F Sbjct: 58 LELSKRVDAVLPVNENLACIEFLNSIKEKFSCPVLFDFEAYRISRDKKKSKDYF 111 >3ICE-A nrPDB Length = 422 Score = 25.8 bits (55), Expect = 7.4, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 15/30 (50%) Query: 70 EYEINGNEGKRSKIVFFTWSPDTAPVRSKM 99 E + E R+KI+F +P A R +M Sbjct: 121 EVNFDKPENARNKILFENLTPLHANSRLRM 150 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.130 0.336 Lambda K H 0.267 0.0397 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 4,876,718 Number of Sequences: 36641 Number of extensions: 163843 Number of successful extensions: 436 Number of sequences better than 10.0: 38 Number of HSP's better than 10.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 324 Number of HSP's gapped (non-prelim): 65 length of query: 143 length of database: 10,336,785 effective HSP length: 88 effective length of query: 55 effective length of database: 7,112,377 effective search space: 391180735 effective search space used: 391180735 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 54 (25.5 bits)