BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q02821 (542 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1WA5-B nrPDB 1090 0.0 1UN0-A nrPDB 905 0.0 5VQI-B nrPDB 577 e-165 4UAD-A nrPDB 507 e-144 4B8J-A nrPDB 506 e-143 4B8O-A nrPDB 485 e-137 4TNM-A nrPDB 483 e-136 3TJ3-A nrPDB 469 e-132 5TBK-A nrPDB 448 e-126 5V5P-C nrPDB 446 e-125 6BVV-A nrPDB 410 e-115 4E4V-A nrPDB 405 e-113 1IAL-A nrPDB 401 e-112 2Z6G-A nrPDB 38 0.011 2Z6H-A nrPDB 37 0.021 1OYZ-A nrPDB 36 0.048 2GL7-A nrPDB 36 0.050 4R10-A nrPDB 35 0.062 3IFQ-A nrPDB 34 0.20 2Q5D-A nrPDB 33 0.25 1M5N-S nrPDB 33 0.26 2QNA-A nrPDB 33 0.26 2OT8-A nrPDB 33 0.46 3L6X-A nrPDB 32 0.56 5ZHX-A nrPDB 32 0.98 5OWU-A nrPDB 31 1.5 2H56-A nrPDB 30 2.9 1QH8-B nrPDB 29 6.1 5MDH-A nrPDB 28 9.8 >1WA5-B nrPDB Length = 530 Score = 1090 bits (2820), Expect = 0.0, Method: Compositional matrix adjust. Identities = 530/530 (100%), Positives = 530/530 (100%) Query: 1 MDNGTDSSTSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIP 60 MDNGTDSSTSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIP Sbjct: 1 MDNGTDSSTSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIP 60 Query: 61 PTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHR 120 PTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHR Sbjct: 61 PTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHR 120 Query: 121 PPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQ 180 PPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQ Sbjct: 121 PPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQ 180 Query: 181 LLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLS 240 LLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLS Sbjct: 181 LLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLS 240 Query: 241 NLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRI 300 NLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRI Sbjct: 241 NLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRI 300 Query: 301 PKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKE 360 PKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKE Sbjct: 301 PKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKE 360 Query: 361 ACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDI 420 ACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDI Sbjct: 361 ACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDI 420 Query: 421 IRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKA 480 IRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKA Sbjct: 421 IRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKA 480 Query: 481 GGMEKIFNCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFG 530 GGMEKIFNCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFG Sbjct: 481 GGMEKIFNCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFG 530 >1UN0-A nrPDB Length = 443 Score = 905 bits (2339), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/443 (99%), Positives = 442/443 (99%) Query: 88 ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEML 147 ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEML Sbjct: 1 ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEML 60 Query: 148 QLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDY 207 QLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDY Sbjct: 61 QLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDY 120 Query: 208 RDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIY 267 RDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIY Sbjct: 121 RDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIY 180 Query: 268 SMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIV 327 SMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIV Sbjct: 181 SMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIV 240 Query: 328 TGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPP 387 TGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPP Sbjct: 241 TGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPP 300 Query: 388 LVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEV 447 LVKLLEVAE KTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEV Sbjct: 301 LVKLLEVAEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEV 360 Query: 448 TLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIET 507 TLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIET Sbjct: 361 TLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIET 420 Query: 508 YFGEEEDAVDETMAPQNAGNTFG 530 YFGEEEDAVDETMAPQNAGNTFG Sbjct: 421 YFGEEEDAVDETMAPQNAGNTFG 443 >5VQI-B nrPDB Length = 495 Score = 577 bits (1488), Expect = e-165, Method: Compositional matrix adjust. Identities = 285/453 (62%), Positives = 355/453 (78%), Gaps = 8/453 (1%) Query: 83 SQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMREN 142 SQL ++LP+M + + S ++ +Q+ AT KFR++LS+E PPI+ VI+ GVV R VEF+R Sbjct: 24 SQLSEDLPKMVEGVFSSEIDKQIQATTKFRKLLSKERNPPIEEVIKTGVVGRFVEFLRSP 83 Query: 143 QPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAG 202 ++Q EAAWALTNIASG++ QT+VV++A AVP+F++LL + +V+EQA+WALGN+AG Sbjct: 84 H-TLVQFEAAWALTNIASGSATQTQVVIEAGAVPIFVELLGSPEPDVREQAVWALGNIAG 142 Query: 203 DSTDYRDYVLQCNAMEPILGLF-NSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPT 261 DS RDYVL C A+ P+L L +S K S++R ATWTLSN CRGK PQPDW+ ++ ALP Sbjct: 143 DSPQCRDYVLSCGALRPLLTLLGDSRKLSMLRNATWTLSNFCRGKTPQPDWNTIAPALPV 202 Query: 262 LAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALR 321 LAKL+YS+D E L+DACWAISYLSDG + IQAVI+ IP+RLVELL H ST VQTPALR Sbjct: 203 LAKLVYSLDDEVLIDACWAISYLSDGSNDKIQAVIEAGIPRRLVELLMHASTSVQTPALR 262 Query: 322 AVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVID 381 +VGNIVTG+D+QTQV+IN G LP L LLSS K+ I+KEACWTISNITAGN+ QIQ+VID Sbjct: 263 SVGNIVTGDDVQTQVIINCGALPCLLSLLSSNKDGIRKEACWTISNITAGNSAQIQSVID 322 Query: 382 ANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIAD 441 AN+IPPL+ LL A+ KT+KEACWAISNA+SGGLQ+PD IRYLV+QGCIKPLCDLL D Sbjct: 323 ANIIPPLIHLLSHADLKTRKEACWAISNATSGGLQKPDQIRYLVAQGCIKPLCDLLACPD 382 Query: 442 NRIIEVTLDALENILKMGEADKEARG---LNINENADFIEKAGGMEKIFNCQQNENDKIY 498 N+II+V LD LENILK+GE DK A G +IN A FIE+ GGMEKI +CQ N N++IY Sbjct: 383 NKIIQVALDGLENILKVGELDKNAAGDGPDSINRYALFIEECGGMEKIHDCQTNANEEIY 442 Query: 499 EKAYKIIETYFGEEEDAVDETMAPQNAGNTFGF 531 KAY IIE YF +E++A DE M Q FGF Sbjct: 443 MKAYNIIEKYFSDEDEAGDEAMGAQ---QQFGF 472 >4UAD-A nrPDB Length = 479 Score = 507 bits (1305), Expect = e-144, Method: Compositional matrix adjust. Identities = 250/435 (57%), Positives = 328/435 (75%), Gaps = 6/435 (1%) Query: 91 QMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAG-VVPRLVEFMRENQPEMLQL 149 +M + L SDD QL+ T KFR++LS+E PPID VI VV R VEF++ N+ LQ Sbjct: 27 EMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQF 86 Query: 150 EAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRD 209 EAAWALTNIASGTS QTK+V++A AVP+FI+LL + +V+EQA+WALGN+AGDS+ RD Sbjct: 87 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRD 146 Query: 210 YVLQCNAMEPILGLFN-SNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYS 268 YVL C+ + P+L L S + ++ R A W LSNLCRGK P P+++ VS LP L++L++S Sbjct: 147 YVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFS 206 Query: 269 MDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVT 328 D++ L DACWA+SYLSDGP E IQAVID + +RLVELL H V +PALRAVGNIVT Sbjct: 207 SDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVT 266 Query: 329 GNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPL 388 G+D+QTQV++N LP L LLSSPKE+I+KEACWTISNITAGN QIQAVIDAN+ P L Sbjct: 267 GDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVL 326 Query: 389 VKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVT 448 +++L+ AE++T+KEA WAI+NA+SGG P+ IRYLVS GCIKPLCDLL + D++I++V Sbjct: 327 IEILQKAEFRTRKEAAWAITNATSGG--TPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVA 384 Query: 449 LDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETY 508 L+ LENIL++GE + + G +N IE+A G++KI Q +EN +IY+KA+ +IE Y Sbjct: 385 LNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHY 444 Query: 509 FGEEEDAVDETMAPQ 523 FG E+D D ++APQ Sbjct: 445 FGVEDD--DSSLAPQ 457 >4B8J-A nrPDB Length = 528 Score = 506 bits (1303), Expect = e-143, Method: Compositional matrix adjust. Identities = 284/531 (53%), Positives = 359/531 (67%), Gaps = 24/531 (4%) Query: 15 EYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDG--ADSDEEDE 72 E RR +K A+E RRRR+ VE+RK++R+E+L K+R +G A + Sbjct: 12 EVRRNRYKVA--VDAEEGRRRREDNMVEIRKSRREESLLKKRR-----EGLQAQAPVPAS 64 Query: 73 SSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVV 132 ++ D++ S LP M + SDD QL AT +FR++LS E PPI+ VIQ+GVV Sbjct: 65 AATGVDKKLES-----LPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVV 119 Query: 133 PRLVEFM-RENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKE 191 PR V+F+ RE+ P+ LQ EAAWALTNIASGTS TKVV+D AVP+F++LL + S +V+E Sbjct: 120 PRFVQFLTREDFPQ-LQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVRE 178 Query: 192 QAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN-KPSLIRTATWTLSNLCRGKKPQP 250 QA+WALGNVAGDS RD VL A+ P+L N + K S++R ATWTLSN CRG KPQP Sbjct: 179 QAVWALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRG-KPQP 237 Query: 251 DWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSH 310 + ALP LA+LI+S D E L DACWA+SYLSDG + IQAVI+ + RLVELL H Sbjct: 238 SFEQTRPALPALARLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLH 297 Query: 311 ESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPA-LRLLLSSPKENIKKEACWTISNIT 369 S V PALR VGNIVTG+D QTQ +I+ LP L LL + K++IKKEACWTISNIT Sbjct: 298 PSPSVLIPALRTVGNIVTGDDAQTQCIIDHQALPCLLSLLTQNLKKSIKKEACWTISNIT 357 Query: 370 AGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGC 429 AGN +QIQAVI+A +I PLV LL+ AE+ KKEA WAISNA+SGG D I+YLVS+GC Sbjct: 358 AGNKDQIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSH--DQIKYLVSEGC 415 Query: 430 IKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNC 489 IKPLCDLL D RI+ V L+ LENILK+GE DK ++N + I++A G+EKI N Sbjct: 416 IKPLCDLLICPDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIENL 475 Query: 490 QQNENDKIYEKAYKIIETYFGEEED---AVDETMAPQNAGNTFGFGSNVNQ 537 Q ++N++IYEKA KI+E Y+ +EED APQ A FG G Q Sbjct: 476 QSHDNNEIYEKAVKILEAYWMDEEDDTMGATTVAAPQGATFDFGQGGGAAQ 526 >4B8O-A nrPDB Length = 490 Score = 485 bits (1248), Expect = e-137, Method: Compositional matrix adjust. Identities = 269/498 (54%), Positives = 338/498 (67%), Gaps = 22/498 (4%) Query: 48 RDEALAK--RRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQL 105 ++ A AK R++ P G D D++ + + + LP M + SDD QL Sbjct: 5 KETAAAKFERQHMDSPDLGTDDDDKAMADIGS----------SLPAMIGGVYSDDNNLQL 54 Query: 106 SATVKFRQILSREHRPPIDVVIQAGVVPRLVEFM-RENQPEMLQLEAAWALTNIASGTSA 164 AT +FR++LS E PPI+ VIQ+GVVPR V+F+ RE+ P+ LQ EAAWALTNIASGTS Sbjct: 55 EATTQFRKLLSIERSPPIEEVIQSGVVPRFVQFLTREDFPQ-LQFEAAWALTNIASGTSE 113 Query: 165 QTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLF 224 TKVV+D AVP+F++LL + S +V+EQA+WALGNVAGDS RD VL A+ P+L Sbjct: 114 NTKVVIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRDLVLANGALLPLLAQL 173 Query: 225 NSN-KPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISY 283 N + K S++R ATWTLSN CRG KPQP + ALP LA+LI+S D E L DACWA+SY Sbjct: 174 NEHTKLSMLRNATWTLSNFCRG-KPQPSFEQTRPALPALARLIHSNDEEVLTDACWALSY 232 Query: 284 LSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVL 343 LSDG + IQAVI+ + RLVELL H S V PALR VGNIVTG+D QTQ +I+ L Sbjct: 233 LSDGTNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQCIIDHQAL 292 Query: 344 PA-LRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKE 402 P L LL + K++IKKEACWTISNITAGN +QIQAVI+A +I PLV LL+ AE+ KKE Sbjct: 293 PCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLLQTAEFDIKKE 352 Query: 403 ACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEAD 462 A WAISNA+SGG D I+YLVS+GCIKPLCDLL D RI+ V L+ LENILK+GE D Sbjct: 353 AAWAISNATSGGSH--DQIKYLVSEGCIKPLCDLLICPDIRIVTVCLEGLENILKVGETD 410 Query: 463 KEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYFGEEED---AVDET 519 K ++N + I++A G+EKI N Q ++N++IYEKA KI+E Y+ +EED Sbjct: 411 KTLAAGDVNVFSQMIDEAEGLEKIENLQSHDNNEIYEKAVKILEAYWMDEEDDTMGATTV 470 Query: 520 MAPQNAGNTFGFGSNVNQ 537 APQ A FG G Q Sbjct: 471 AAPQGATFDFGQGGGAAQ 488 >4TNM-A nrPDB Length = 531 Score = 483 bits (1242), Expect = e-136, Method: Compositional matrix adjust. Identities = 275/532 (51%), Positives = 358/532 (67%), Gaps = 16/532 (3%) Query: 15 EYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESS 74 E RR +K A+E RRRR+ VE+RK KR+E L K+R G+ + + ++ Sbjct: 10 EVRRNRYKVA--VDAEEGRRRREDNLVEIRKNKREENLQKKRFTSSMAFGSATGQTEQDL 67 Query: 75 VSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPR 134 SA+Q L+ LP M + S+D QL AT R++LS E PPI+ V+Q+GVVPR Sbjct: 68 SSANQ-----LKDNLPAMVAGIWSEDSNSQLEATNLLRKLLSIEQNPPINEVVQSGVVPR 122 Query: 135 LVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAI 194 +V+F+ + LQ EAAWALTNIASGTS T V++++ AVP+FIQLL + S +V+EQA+ Sbjct: 123 VVKFLSRDDFPKLQFEAAWALTNIASGTSENTNVIIESGAVPIFIQLLSSASEDVREQAV 182 Query: 195 WALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN-KPSLIRTATWTLSNLCRGKKPQPDWS 253 WALGNVAGDS RD VL AM P+L FN N K S++R ATWTLSN CRGK P P + Sbjct: 183 WALGNVAGDSPKCRDLVLSYGAMTPLLSQFNENTKLSMLRNATWTLSNFCRGKPP-PAFE 241 Query: 254 VVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHEST 313 ALP L +L+ SMD E L DACWA+SYLSD + IQAVI+ + RL++LL H S Sbjct: 242 QTQPALPVLERLVQSMDEEVLTDACWALSYLSDNSNDKIQAVIEAGVVPRLIQLLGHSSP 301 Query: 314 LVQTPALRAVGNIVTGNDLQTQVVINAGVLPA-LRLLLSSPKENIKKEACWTISNITAGN 372 V PALR +GNIVTG+DLQTQ+V++ LP L LL ++ K++IKKEACWTISNITAGN Sbjct: 302 SVLIPALRTIGNIVTGDDLQTQMVLDQQALPCLLNLLKNNYKKSIKKEACWTISNITAGN 361 Query: 373 TEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKP 432 +QIQAVIDA +I LV +L+ AE++ KKEA W ISNA+SGG D I+++VSQGCIKP Sbjct: 362 ADQIQAVIDAGIIQSLVWVLQSAEFEVKKEAAWGISNATSGGTH--DQIKFMVSQGCIKP 419 Query: 433 LCDLLEIADNRIIEVTLDALENILKMGEADKE-ARGLNINENADFIEKAGGMEKIFNCQQ 491 LCDLL D +++ V L+ALENIL +GEA+K N A I++A G+EKI N Q Sbjct: 420 LCDLLTCPDLKVVTVCLEALENILVVGEAEKNLGHTGEDNLYAQMIDEAEGLEKIENLQS 479 Query: 492 NENDKIYEKAYKIIETYF--GEEEDAVDETMAPQNAGNTFGFGSNVNQQFNF 541 ++N+ IY+KA KI+ET++ EE+ DE APQ +G FG + QFNF Sbjct: 480 HDNNDIYDKAVKILETFWTEDNEEEGNDENHAPQ-SGFQFGSTNVPPGQFNF 530 >3TJ3-A nrPDB Length = 447 Score = 469 bits (1208), Expect = e-132, Method: Compositional matrix adjust. Identities = 238/425 (56%), Positives = 314/425 (73%), Gaps = 4/425 (0%) Query: 92 MTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQA-GVVPRLVEFMRENQPEMLQLE 150 M + + S ++QLSAT KFR++LS+E PPID VI GVV R VEF++ + LQ E Sbjct: 22 MIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFE 81 Query: 151 AAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDY 210 +AW LTNIASG S QT++V+ A AVP+FI+LL + +V+EQA+WALGN+AGDST RDY Sbjct: 82 SAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDY 141 Query: 211 VLQCNAMEPILGLFNS-NKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSM 269 VL CN + P+L LF+ N+ ++ R A W LSNLCRGK P P+++ VS L L+ L++ Sbjct: 142 VLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVS 201 Query: 270 DTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTG 329 DT+ L DACWA+SYLSDGP + IQAVID + +RLVELL H V +PALRAVGNIVTG Sbjct: 202 DTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 261 Query: 330 NDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLV 389 +D+QTQV++N L +L LLSSPKE+IKKEACWTISNITAGN QIQ VIDAN+ P L+ Sbjct: 262 DDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALI 321 Query: 390 KLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTL 449 +L+ AE++T+KEA WAI+NA+SGG + I+YLV GCIKPLCDLL + D++I++V L Sbjct: 322 SILQTAEFRTRKEAAWAITNATSGG--SAEQIKYLVELGCIKPLCDLLTVMDSKIVQVAL 379 Query: 450 DALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYF 509 + LENIL++GE + + G IN IE+A G++KI Q +EN +IY+KA+ +IE YF Sbjct: 380 NGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYF 439 Query: 510 GEEED 514 G E++ Sbjct: 440 GTEDE 444 >5TBK-A nrPDB Length = 521 Score = 448 bits (1153), Expect = e-126, Method: Compositional matrix adjust. Identities = 243/522 (46%), Positives = 325/522 (62%), Gaps = 21/522 (4%) Query: 17 RRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESSVS 76 R NFKNKGR + +RR+R+ VELRK KRDE L KRRN +P D + +S + Sbjct: 11 RLKNFKNKGR-DLETMRRQRNEVVVELRKNKRDEHLLKRRN-VPHEDICE-----DSDID 63 Query: 77 ADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLV 136 D Y L + Q +SD+ QLSA R++LS + PPID +I++G++P LV Sbjct: 64 GD---YRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILV 120 Query: 137 EFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWA 196 + + LQ EAAWALTNIASGTS QT+ VV ++AVPLF++LL++ V EQA+WA Sbjct: 121 HCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWA 180 Query: 197 LGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKP-SLIRTATWTLSNLCRGKKPQPDWSVV 255 LGN+ GD RDYV+ ++P+L + + P + +R TW + NLCR K P P + Sbjct: 181 LGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETI 240 Query: 256 SQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLV 315 + LP L LI+ D LVD WA+SYL+D E IQ VID I LV LLSH+ V Sbjct: 241 QEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKV 300 Query: 316 QTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQ 375 QT ALRAVGNIVTG D QTQVV+N L LL+ PKE I KEA W +SNITAGN +Q Sbjct: 301 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQ 360 Query: 376 IQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCD 435 +QAVIDANL+P ++ LL+ ++ T+KEA WAISN + G R D + YL+ Q I P C+ Sbjct: 361 VQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISG--RKDQVAYLIQQNVIPPFCN 418 Query: 436 LLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNEND 495 LL + D ++++V LD L NILKM E + E G + IE+ GG+EKI Q +EN+ Sbjct: 419 LLTVKDAQVVQVVLDGLSNILKMAEDEAETIG-------NLIEECGGLEKIEQLQNHENE 471 Query: 496 KIYEKAYKIIETYFGEEEDAVDETMAPQNA-GNTFGFGSNVN 536 IY+ AY+II+ +F ++ D ++ P+ G TFGF S+ N Sbjct: 472 DIYKLAYEIIDQFFSSDDIDEDPSLVPEAIQGGTFGFNSSAN 513 >5V5P-C nrPDB Length = 528 Score = 446 bits (1147), Expect = e-125, Method: Compositional matrix adjust. Identities = 238/524 (45%), Positives = 332/524 (63%), Gaps = 20/524 (3%) Query: 13 VPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDE 72 +P R FKNKG+ S E+RRRR VELRKAK+DE + KRRN D A S ++ Sbjct: 8 LPAARLNRFKNKGKDST-EMRRRRIEVNVELRKAKKDEQMLKRRNVSSFPDDATSPLQE- 65 Query: 73 SSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVV 132 ++ + + + + +NS++++ QL AT R++LSRE +PPID +I+AG++ Sbjct: 66 -----NRNNQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLI 120 Query: 133 PRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQ 192 P+ V F+ + +Q E+AWALTNIASGTS QTK VVD A+P FI LL + + EQ Sbjct: 121 PKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQ 180 Query: 193 AIWALGNVAGDSTDYRDYVLQCNAMEPILGLF-----NSNKPSLIRTATWTLSNLCRGKK 247 A+WALGN+AGD + +RD V++ A++P+L L ++ +R TWTLSNLCR K Sbjct: 181 AVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKN 240 Query: 248 PQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVEL 307 P P V Q LPTL +L++ D E L D+CWAISYL+DGP E I+ V+ + +LV+L Sbjct: 241 PAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKL 300 Query: 308 LSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISN 367 L + TPALRA+GNIVTG D QTQ VI+AG L LL++PK NI+KEA WT+SN Sbjct: 301 LGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSN 360 Query: 368 ITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQ 427 ITAG +QIQ V++ L+P LV +L A++KT+KEA WAI+N +SGG + I YLV Sbjct: 361 ITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTV--EQIVYLVHC 418 Query: 428 GCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIF 487 G I+PL +LL D +II+V LDA+ NI + E E L+I IE+ GG++KI Sbjct: 419 GIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSI-----MIEECGGLDKIE 473 Query: 488 NCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFGF 531 Q++EN+ +Y+ + +IE YF EE+ D+ + P+ F F Sbjct: 474 ALQRHENESVYKASLNLIEKYFSVEEEE-DQNVVPETTSEGFAF 516 >6BVV-A nrPDB Length = 459 Score = 410 bits (1055), Expect = e-115, Method: Compositional matrix adjust. Identities = 213/450 (47%), Positives = 287/450 (63%), Gaps = 11/450 (2%) Query: 89 LPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQ 148 L + Q +SD+ QLSA R++LS + PPID +I++G++P LV + + LQ Sbjct: 11 LEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQ 70 Query: 149 LEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYR 208 EAAWALTNIASGTS QT+ VV ++AVPLF++LL++ V EQA+WALGN+ GD R Sbjct: 71 FEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCR 130 Query: 209 DYVLQCNAMEPILGLFNSNKP-SLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIY 267 DYV+ ++P+L + + P + +R TW + NLCR K P P + + LP L LI+ Sbjct: 131 DYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIH 190 Query: 268 SMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIV 327 D LVD WA+SYL+D E IQ VID I LV LLSH+ VQT ALRAVGNIV Sbjct: 191 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIV 250 Query: 328 TGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPP 387 TG D QTQVV+N L LL+ PKE I KEA W +SNITAGN +Q+QAVIDANL+P Sbjct: 251 TGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPM 310 Query: 388 LVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEV 447 ++ LL+ ++ T+KEA WAISN + G R D + YL+ Q I P C+LL + D ++++V Sbjct: 311 IIHLLDKGDFGTQKEAAWAISNLTISG--RKDQVAYLIQQNVIPPFCNLLTVKDAQVVQV 368 Query: 448 TLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIET 507 LD L NILKM E + E G + IE+ GG+EKI Q +EN+ IY+ AY+II+ Sbjct: 369 VLDGLSNILKMAEDEAETIG-------NLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQ 421 Query: 508 YFGEEEDAVDETMAPQNA-GNTFGFGSNVN 536 +F ++ D ++ P+ G TFGF S+ N Sbjct: 422 FFSSDDIDEDPSLVPEAIQGGTFGFNSSAN 451 >4E4V-A nrPDB Length = 485 Score = 405 bits (1040), Expect = e-113, Method: Compositional matrix adjust. Identities = 214/457 (46%), Positives = 290/457 (63%), Gaps = 15/457 (3%) Query: 92 MTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEA 151 + + +NS +++ QL AT R++LSRE +PPID +I+AG++P+ V F+ +Q E+ Sbjct: 37 IVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFES 96 Query: 152 AWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYV 211 AWALTNIASGTS QTK VVD A+P FI LL + + EQA+WALGN+AGD + +RD V Sbjct: 97 AWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLV 156 Query: 212 LQCNAMEPILGLF-----NSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLI 266 ++ A++P+L L +S +R TWTLSNLCR K P P V Q LPTL +L+ Sbjct: 157 IKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLL 216 Query: 267 YSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNI 326 + D E L D CWAISYL+DGP E I V+ + +LV+LL + TPALRA+GNI Sbjct: 217 HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNI 276 Query: 327 VTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIP 386 VTG D QTQVVI+AG L LL++PK NI+KEA WT+SNITAG +QIQ V++ L+P Sbjct: 277 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVP 336 Query: 387 PLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIE 446 LV +L A++KT+KEA WA++N +SGG + I YLV G I+PL +LL D +II Sbjct: 337 FLVSVLSKADFKTQKEAVWAVTNYTSGG--TVEQIVYLVHCGIIEPLMNLLTAKDTKIIL 394 Query: 447 VTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIE 506 V LDA+ NI + E E L+I IE+ GG++KI Q +EN+ +Y + +IE Sbjct: 395 VILDAISNIFQAAEKLGETEKLSI-----MIEECGGLDKIEALQNHENESVYRASLSLIE 449 Query: 507 TYFGEEEDAVDETMAPQNA--GNTFGFGSNVNQQFNF 541 YF EE+ D+ + P+ G TF FNF Sbjct: 450 KYFSVEEEE-DQNVVPETTSEGYTFQVQDGAPGTFNF 485 >1IAL-A nrPDB Length = 453 Score = 401 bits (1031), Expect = e-112, Method: Compositional matrix adjust. Identities = 212/466 (45%), Positives = 298/466 (63%), Gaps = 18/466 (3%) Query: 49 DEALAKRRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSAT 108 DE + KRRN D A S ++ ++ + + + + +NS++++ QL AT Sbjct: 1 DEQMLKRRNVSSFPDDATSPLQE------NRNNQGTVNWSVEDIVKGINSNNLESQLQAT 54 Query: 109 VKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKV 168 R++LSRE +PPID +I+AG++P+ V F+ + +Q E+AWALTNIASGTS QTK Sbjct: 55 QAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKA 114 Query: 169 VVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLF---- 224 VVD A+P FI LL + + EQA+WALGN+AGD + +RD V++ A++P+L L Sbjct: 115 VVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPD 174 Query: 225 -NSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISY 283 ++ +R TWTLSNLCR K P P V Q LPTL +L++ D E L D+CWAISY Sbjct: 175 LSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISY 234 Query: 284 LSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVL 343 L+DGP E I+ V+ + +LV+LL + TPALRA+GNIVTG D QTQ VI+AG L Sbjct: 235 LTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGAL 294 Query: 344 PALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEA 403 LL++PK NI+KEA WT+SNITAG +QIQ V++ L+P LV +L A++KT+KEA Sbjct: 295 AVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEA 354 Query: 404 CWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADK 463 WAI+N +SGG + I YLV G I+PL +LL D +II+V LDA+ NI + E Sbjct: 355 AWAITNYTSGG--TVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLG 412 Query: 464 EARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYF 509 E L+I IE+ GG++KI Q++EN+ +Y+ + +IE YF Sbjct: 413 ETEKLSI-----MIEECGGLDKIEALQRHENESVYKASLNLIEKYF 453 >2Z6G-A nrPDB Length = 780 Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust. Identities = 34/168 (20%), Positives = 75/168 (44%), Gaps = 6/168 (3%) Query: 211 VLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMD 270 + + + ++ + S S++ A TL NL ++ ++ L + L+ + Sbjct: 230 IFKSGGIPALVNMLGSPVDSVLFHAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTN 289 Query: 271 TETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELL---SHESTLVQTPALRAVGNIV 327 + L + L+ G QE+ ++ P+ LV ++ ++E L T + V ++ Sbjct: 290 VKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVC 349 Query: 328 TGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQ 375 + N ++ AG + AL L L+ P + + + WT+ N++ T+Q Sbjct: 350 SSNK---PAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQ 394 >2Z6H-A nrPDB Length = 644 Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust. Identities = 34/168 (20%), Positives = 75/168 (44%), Gaps = 6/168 (3%) Query: 211 VLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMD 270 + + + ++ + S S++ A TL NL ++ ++ L + L+ + Sbjct: 94 IFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTN 153 Query: 271 TETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELL---SHESTLVQTPALRAVGNIV 327 + L + L+ G QE+ ++ P+ LV ++ ++E L T + V ++ Sbjct: 154 VKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVC 213 Query: 328 TGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQ 375 + N ++ AG + AL L L+ P + + + WT+ N++ T+Q Sbjct: 214 SSNK---PAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQ 258 >1OYZ-A nrPDB Length = 280 Score = 35.8 bits (81), Expect = 0.048, Method: Compositional matrix adjust. Identities = 36/147 (24%), Positives = 59/147 (40%), Gaps = 23/147 (15%) Query: 145 EMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDS 204 E Q+ A TN+ T+ V+ D +PL I LL + +V+ A +A+ D+ Sbjct: 131 EQSQITAFDKSTNVRRATAFAISVINDKATIPLLINLLKDPNGDVRNWAAFAININKYDN 190 Query: 205 TDYRDYVLQC-------NAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQ 257 +D RD ++ +E I+GL R LS LC K + + + Sbjct: 191 SDIRDCFVEMLQDKNEEVRIEAIIGLS-------YRKDKRVLSVLCDELKKNTVYDDIIE 243 Query: 258 A---------LPTLAKLIYSMDTETLV 275 A LP L ++Y D ++ Sbjct: 244 AAGELGDKTLLPVLDTMLYKFDDNEII 270 >2GL7-A nrPDB Length = 550 Score = 35.8 bits (81), Expect = 0.050, Method: Compositional matrix adjust. Identities = 34/168 (20%), Positives = 75/168 (44%), Gaps = 6/168 (3%) Query: 211 VLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMD 270 + + + ++ + S S++ A TL NL ++ ++ L + L+ + Sbjct: 95 IFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTN 154 Query: 271 TETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELL---SHESTLVQTPALRAVGNIV 327 + L + L+ G QE+ ++ P+ LV ++ ++E L T + V ++ Sbjct: 155 VKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVC 214 Query: 328 TGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQ 375 + N ++ AG + AL L L+ P + + + WT+ N++ T+Q Sbjct: 215 SSNK---PAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQ 259 >4R10-A nrPDB Length = 572 Score = 35.4 bits (80), Expect = 0.062, Method: Compositional matrix adjust. Identities = 59/230 (25%), Positives = 92/230 (40%), Gaps = 19/230 (8%) Query: 178 FIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATW 237 I++LY V A+ L N+ +D R NA+E + + P L+ Sbjct: 119 IIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQARALNAVEALTPHLHKTNPKLLAQVAD 178 Query: 238 TLSNLCRGKKPQPDWSVVSQALPTLAKLI---YSMDTETLVDACWAISYLSDGPQEAIQA 294 L L P + +S P + I YS + + I LS P Sbjct: 179 GLYFLLIDDAPS-KITFLSLLGPQILVSILREYSDHRKLIYTVVRCIRSLSVCPSNKPAL 237 Query: 295 VIDVRIPKRLVELLSHESTLVQTPALRAVGNI---VTGNDLQTQVVINAGVLPALRLLLS 351 + +P VEL + + QT L A+ N+ T + TQ++I +L +R+ Sbjct: 238 ISLGCLPALYVELCTAKDERSQTAILVAMRNLSDSATNEENLTQLIIK--LLEIIRV--- 292 Query: 352 SPKENIKKEACWTISNITAGNTEQIQAV-----IDANLIPPLVKLLEVAE 396 + + AC T+SN+T NT Q V IDA L+ + +L EV E Sbjct: 293 -ANDGMTACACGTLSNLTCNNTRNKQTVCSHGGIDA-LVTAIRRLPEVEE 340 >3IFQ-A nrPDB Length = 553 Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust. Identities = 82/407 (20%), Positives = 162/407 (39%), Gaps = 64/407 (15%) Query: 134 RLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVP-LFIQLLYTGSVEVKEQ 192 ++V + +N P+ L + L +A G ++K+++ A+ P +Q++ S E + Sbjct: 149 KMVPLLNKNNPKFLAITTD-CLQLLAYGNQ-ESKLIILANGGPQALVQIMRNYSYE---K 203 Query: 193 AIWALG---NVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQ 249 +W V + +++ M+ + SN P L++ WTL NL Sbjct: 204 LLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNL------- 256 Query: 250 PDWSVVSQALPTLAKLIYSM----DTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLV 305 D + + L ++ K++ + D L A +S L+ + V + L+ Sbjct: 257 SDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI 316 Query: 306 E--LLSHESTLVQTPALRAVGNIVTGND----LQTQVVINAGVLPALRLLLSSPKE-NIK 358 L + + + PA+ A+ ++ + + Q V +N G+ PA+ LL+ P + + Sbjct: 317 HAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGI-PAIVKLLNQPNQWPLV 375 Query: 359 KEACWTISNIT--AGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQ 416 K I N+ N +Q +A +IP LV+LL A ++ + G++ Sbjct: 376 KATIGLIRNLALCPANHAPLQ---EAAVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVR 432 Query: 417 RPDIIRYLVSQGCIKPLCDLLEIADNRI-----------IEVTLDALENILKMGEA---- 461 +I+ +GC L L NR+ +++ ++ENI ++ Sbjct: 433 MEEIV-----EGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCE 487 Query: 462 ---DKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKII 505 DKEA AD I+ G + + N+ A ++ Sbjct: 488 LAQDKEA--------ADAIDAEGASAPLMELLHSRNEGTATYAAAVL 526 Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust. Identities = 27/120 (22%), Positives = 54/120 (45%) Query: 249 QPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELL 308 Q D + ++ALP L KL+ D + A ++ LS + ++ +V + Sbjct: 11 QDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTM 70 Query: 309 SHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNI 368 + S L ++ + ++ + + +G +PAL +LSSP E++ A T+ N+ Sbjct: 71 QNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNL 130 >2Q5D-A nrPDB Length = 876 Score = 33.5 bits (75), Expect = 0.25, Method: Compositional matrix adjust. Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 17/122 (13%) Query: 131 VVPRLVEFMREN--QPEMLQLEAA-WALTNIASGTS-AQTKVVVDADAVPLFIQLLYTGS 186 +VP ++ F++E+ P+ +AA A I G +Q K +V A+P I+L+ S Sbjct: 363 IVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLV-IQAMPTLIELMKDPS 421 Query: 187 VEVKEQAIWALGNV------AGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLS 240 V V++ A W +G + A + Y +LQC I GL S +P + W S Sbjct: 422 VVVRDTAAWTVGRICELLPEAAINDVYLAPLLQC----LIEGL--SAEPRVASNVCWAFS 475 Query: 241 NL 242 +L Sbjct: 476 SL 477 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 6/124 (4%) Query: 254 VVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHEST 313 +V LP + + I + D A A + +GP+ + + ++ L+EL+ S Sbjct: 363 IVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSV 422 Query: 314 LVQTPALRAVGNIVTGNDLQTQVVINAGVL-PALRLLLS--SPKENIKKEACWTISNITA 370 +V+ A VG I +L + IN L P L+ L+ S + + CW S++ Sbjct: 423 VVRDTAAWTVGRIC---ELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAE 479 Query: 371 GNTE 374 E Sbjct: 480 AAYE 483 Score = 30.4 bits (67), Expect = 2.2, Method: Compositional matrix adjust. Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 8/106 (7%) Query: 190 KEQAIWALGNV--AGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKK 247 ++ A+ A G + + + + V+Q AM ++ L + TA WT+ +C Sbjct: 383 RDAAVMAFGCILEGPEPSQLKPLVIQ--AMPTLIELMKDPSVVVRDTAAWTVGRICE-LL 439 Query: 248 PQPDWSVVSQALPTLAKLIYSMDTETLV--DACWAISYLSDGPQEA 291 P+ + V A P L LI + E V + CWA S L++ EA Sbjct: 440 PEAAINDVYLA-PLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEA 484 >1M5N-S nrPDB Length = 485 Score = 33.5 bits (75), Expect = 0.26, Method: Compositional matrix adjust. Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 17/122 (13%) Query: 131 VVPRLVEFMREN--QPEMLQLEAA-WALTNIASGTS-AQTKVVVDADAVPLFIQLLYTGS 186 +VP ++ F++E+ P+ +AA A I G +Q K +V A+P I+L+ S Sbjct: 363 IVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLV-IQAMPTLIELMKDPS 421 Query: 187 VEVKEQAIWALGNV------AGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLS 240 V V++ A W +G + A + Y +LQC I GL S +P + W S Sbjct: 422 VVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCL----IEGL--SAEPRVASNVCWAFS 475 Query: 241 NL 242 +L Sbjct: 476 SL 477 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 6/124 (4%) Query: 254 VVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHEST 313 +V LP + + I + D A A + +GP+ + + ++ L+EL+ S Sbjct: 363 IVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSV 422 Query: 314 LVQTPALRAVGNIVTGNDLQTQVVINAGVL-PALRLLLS--SPKENIKKEACWTISNITA 370 +V+ A VG I +L + IN L P L+ L+ S + + CW S++ Sbjct: 423 VVRDTAAWTVGRIC---ELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAE 479 Query: 371 GNTE 374 E Sbjct: 480 AAYE 483 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 8/106 (7%) Query: 190 KEQAIWALGNV--AGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKK 247 ++ A+ A G + + + + V+Q AM ++ L + TA WT+ +C Sbjct: 383 RDAAVMAFGCILEGPEPSQLKPLVIQ--AMPTLIELMKDPSVVVRDTAAWTVGRICE-LL 439 Query: 248 PQPDWSVVSQALPTLAKLIYSMDTETLV--DACWAISYLSDGPQEA 291 P+ + V A P L LI + E V + CWA S L++ EA Sbjct: 440 PEAAINDVYLA-PLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEA 484 >2QNA-A nrPDB Length = 762 Score = 33.5 bits (75), Expect = 0.26, Method: Compositional matrix adjust. Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 17/122 (13%) Query: 131 VVPRLVEFMREN--QPEMLQLEAA-WALTNIASGTS-AQTKVVVDADAVPLFIQLLYTGS 186 +VP ++ F++E+ P+ +AA A I G +Q K +V A+P I+L+ S Sbjct: 238 IVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLV-IQAMPTLIELMKDPS 296 Query: 187 VEVKEQAIWALGNV------AGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLS 240 V V++ A W +G + A + Y +LQC I GL S +P + W S Sbjct: 297 VVVRDTAAWTVGRICELLPEAAINDVYLAPLLQC----LIEGL--SAEPRVASNVCWAFS 350 Query: 241 NL 242 +L Sbjct: 351 SL 352 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 8/106 (7%) Query: 190 KEQAIWALGNV--AGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKK 247 ++ A+ A G + + + + V+Q AM ++ L + TA WT+ +C Sbjct: 258 RDAAVMAFGCILEGPEPSQLKPLVIQ--AMPTLIELMKDPSVVVRDTAAWTVGRICE-LL 314 Query: 248 PQPDWSVVSQALPTLAKLIYSMDTETLV--DACWAISYLSDGPQEA 291 P+ + V A P L LI + E V + CWA S L++ EA Sbjct: 315 PEAAINDVYLA-PLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEA 359 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 6/124 (4%) Query: 254 VVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHEST 313 +V LP + + I + D A A + +GP+ + + ++ L+EL+ S Sbjct: 238 IVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSV 297 Query: 314 LVQTPALRAVGNIVTGNDLQTQVVINAGVL-PALRLLLS--SPKENIKKEACWTISNITA 370 +V+ A VG I +L + IN L P L+ L+ S + + CW S++ Sbjct: 298 VVRDTAAWTVGRIC---ELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAE 354 Query: 371 GNTE 374 E Sbjct: 355 AAYE 358 >2OT8-A nrPDB Length = 852 Score = 32.7 bits (73), Expect = 0.46, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 1/105 (0%) Query: 304 LVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACW 363 L ELL H +V+ + +G I G +Q + ++P L LS K ++ CW Sbjct: 364 LKELLFHHEWVVKESGILVLGAIAEGC-MQGMIPYLPELIPHLIQCLSDKKALVRSITCW 422 Query: 364 TISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAIS 408 T+S Q L+ L+K + + + ++ AC A + Sbjct: 423 TLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFA 467 Score = 32.0 bits (71), Expect = 0.76, Method: Compositional matrix adjust. Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 5/114 (4%) Query: 175 VPLFIQLLYTGSVEVKEQAIWALGNVA-GDSTDYRDYVLQCNAMEPILGLFNSNKPSLIR 233 +PL +LL+ VKE I LG +A G Y+ + + P L S+K +L+R Sbjct: 361 LPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPE---LIPHLIQCLSDKKALVR 417 Query: 234 TAT-WTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSD 286 + T WTLS QP + + + L K I + AC A + L + Sbjct: 418 SITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEE 471 >3L6X-A nrPDB Length = 584 Score = 32.3 bits (72), Expect = 0.56, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 343 LPALRLLLSSPKENIKKEACWTISNITAGNTEQIQ-AVIDANLIPPLVKLLEVA 395 +P L LL PK+ + AC + NI+ G + + A+ + + +P LV+LL A Sbjct: 92 IPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKA 145 >5ZHX-A nrPDB Length = 487 Score = 31.6 bits (70), Expect = 0.98, Method: Compositional matrix adjust. Identities = 45/156 (28%), Positives = 70/156 (44%), Gaps = 19/156 (12%) Query: 296 IDVRIPKRLVELLSHESTLVQTPALRAVGNIVT-GNDLQTQVVINAGVLPALRLLLSSPK 354 +D + LV+LL+ + V RA+GNI + LQ Q+ IN GV+P L LL Sbjct: 15 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQL-INMGVIPTLVKLLGIHC 73 Query: 355 ENIK-KEACWTISNITAGNTEQIQA----VIDANLIPPLVKLLEVAEYKTKKEACWAISN 409 +N E C + GN ++++ N+ LVKL + K+E + + Sbjct: 74 QNAALTEMCL----VAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEV-- 127 Query: 410 ASSGGLQRPDIIRY-LVSQGCIKPLCDLLEIADNRI 444 L D I+ LV G ++ C LLEI ++ Sbjct: 128 --LAPLAENDAIKLQLVEAGLVE--C-LLEIVQQKV 158 >5OWU-A nrPDB Length = 861 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 6/95 (6%) Query: 151 AAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVA---GDSTDY 207 A A +I G + A+P + L+ S++VKE W +G +A +S D Sbjct: 389 AVMAFGSIMDGPDKVQRTYYVHQALPSILNLMNDQSLQVKETTAWCIGRIADSVAESIDP 448 Query: 208 RDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNL 242 + + L ++GL + P + +WT+ NL Sbjct: 449 QQH-LPGVVQACLIGL--QDHPKVATNCSWTIINL 480 >2H56-A nrPDB Length = 233 Score = 30.0 bits (66), Expect = 2.9, Method: Compositional matrix adjust. Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 11/97 (11%) Query: 119 HRPPIDVVIQAGVVPRLVEFMRE-------NQPEMLQLEAAWALTNIASGTSAQTKVVVD 171 +R + + QAGV R +E++R + + +LE A A T I T+ + Sbjct: 91 YRVSDEALRQAGVSKRKIEYIRHVCEHVESGRLDFTELEGAEATTVIEKLTAIKGIGQWT 150 Query: 172 ADAVPLF----IQLLYTGSVEVKEQAIWALGNVAGDS 204 A+ +F + +L G V ++ A W GN GD Sbjct: 151 AEMFMMFSLGRLDVLSVGDVGLQRGAKWLYGNGEGDG 187 >1QH8-B nrPDB Length = 519 Score = 28.9 bits (63), Expect = 6.1, Method: Compositional matrix adjust. Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 15/112 (13%) Query: 349 LLSSPKENIKKEACWTISNITAGNTEQIQA----VIDANLIPPLVKLLEVAEYKTKK--E 402 LLS P E + A + G T+Q ID L+ P L K+KK + Sbjct: 249 LLSDPSEVLDTPADGHYRMYSGGTTQQEMKEAPDAIDTLLLQPWQLL------KSKKVVQ 302 Query: 403 ACW---AISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDA 451 W A A GL D + VSQ KP+ D L + R++++ LD+ Sbjct: 303 EMWNQPATEVAIPLGLAATDELLMTVSQLSGKPIADALTLERGRLVDMMLDS 354 >5MDH-A nrPDB Length = 333 Score = 28.1 bits (61), Expect = 9.8, Method: Compositional matrix adjust. Identities = 29/128 (22%), Positives = 55/128 (42%), Gaps = 13/128 (10%) Query: 387 PLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIE 446 P+ L+ A + ++I N S G +P I+ L I P+ +L+ + + Sbjct: 3 PIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLL----DITPMMGVLDGVLMELQD 58 Query: 447 VTLDALENILKMGEADKEARGLNINENADFIEKAGGME---------KIFNCQQNENDKI 497 L L++++ + + + L++ + + GME KIF CQ DK Sbjct: 59 CALPLLKDVIATDKEEIAFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKY 118 Query: 498 YEKAYKII 505 +K+ K+I Sbjct: 119 AKKSVKVI 126 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1WA5-B nrPDB 867 0.0 5V5P-C nrPDB 806 0.0 4B8J-A nrPDB 800 0.0 5TBK-A nrPDB 772 0.0 4TNM-A nrPDB 770 0.0 4B8O-A nrPDB 755 0.0 5VQI-B nrPDB 736 0.0 1UN0-A nrPDB 734 0.0 4E4V-A nrPDB 730 0.0 1IAL-A nrPDB 724 0.0 4UAD-A nrPDB 723 0.0 6BVV-A nrPDB 710 0.0 3TJ3-A nrPDB 687 0.0 Sequences not found previously or not previously below threshold: 2Z6G-A nrPDB 59 4e-09 2GL7-A nrPDB 59 6e-09 2Z6H-A nrPDB 59 7e-09 4R10-A nrPDB 58 1e-08 3IFQ-A nrPDB 57 2e-08 5ZHX-A nrPDB 56 4e-08 3L6X-A nrPDB 49 6e-06 2QNA-A nrPDB 42 5e-04 2Q5D-A nrPDB 42 6e-04 1M5N-S nrPDB 40 0.003 2OT8-A nrPDB 37 0.019 3SL9-A nrPDB 37 0.020 1OYZ-A nrPDB 37 0.027 4XRI-A nrPDB 36 0.047 4G3A-A nrPDB 35 0.064 5OWU-A nrPDB 35 0.12 1K8C-A nrPDB 33 0.40 3DA4-A nrPDB 33 0.43 5AVO-A nrPDB 31 1.1 5L9W-A nrPDB 31 1.4 4U15-A nrPDB 31 1.7 4U14-A nrPDB 31 1.7 5DIS-C nrPDB 29 4.4 3NC0-B nrPDB 29 4.4 4V61-AU nrPDB 29 6.8 5WVI-Z nrPDB 29 8.5 >1WA5-B nrPDB Length = 530 Score = 867 bits (2241), Expect = 0.0, Method: Composition-based stats. Identities = 530/530 (100%), Positives = 530/530 (100%) Query: 1 MDNGTDSSTSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIP 60 MDNGTDSSTSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIP Sbjct: 1 MDNGTDSSTSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIP 60 Query: 61 PTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHR 120 PTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHR Sbjct: 61 PTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHR 120 Query: 121 PPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQ 180 PPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQ Sbjct: 121 PPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQ 180 Query: 181 LLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLS 240 LLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLS Sbjct: 181 LLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLS 240 Query: 241 NLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRI 300 NLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRI Sbjct: 241 NLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRI 300 Query: 301 PKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKE 360 PKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKE Sbjct: 301 PKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKE 360 Query: 361 ACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDI 420 ACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDI Sbjct: 361 ACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDI 420 Query: 421 IRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKA 480 IRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKA Sbjct: 421 IRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKA 480 Query: 481 GGMEKIFNCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFG 530 GGMEKIFNCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFG Sbjct: 481 GGMEKIFNCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFG 530 >5V5P-C nrPDB Length = 528 Score = 806 bits (2082), Expect = 0.0, Method: Composition-based stats. Identities = 241/536 (44%), Positives = 335/536 (62%), Gaps = 22/536 (4%) Query: 13 VPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDE 72 +P R FKNKG+ S E+RRRR VELRKAK+DE + KRRN D A S ++ Sbjct: 8 LPAARLNRFKNKGKDST-EMRRRRIEVNVELRKAKKDEQMLKRRNVSSFPDDATSPLQE- 65 Query: 73 SSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVV 132 ++ + + + + +NS++++ QL AT R++LSRE +PPID +I+AG++ Sbjct: 66 -----NRNNQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLI 120 Query: 133 PRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQ 192 P+ V F+ + +Q E+AWALTNIASGTS QTK VVD A+P FI LL + + EQ Sbjct: 121 PKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQ 180 Query: 193 AIWALGNVAGDSTDYRDYVLQCNAMEPILGLF-----NSNKPSLIRTATWTLSNLCRGKK 247 A+WALGN+AGD + +RD V++ A++P+L L ++ +R TWTLSNLCR K Sbjct: 181 AVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKN 240 Query: 248 PQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVEL 307 P P V Q LPTL +L++ D E L D+CWAISYL+DGP E I+ V+ + +LV+L Sbjct: 241 PAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKL 300 Query: 308 LSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISN 367 L + TPALRA+GNIVTG D QTQ VI+AG L LL++PK NI+KEA WT+SN Sbjct: 301 LGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSN 360 Query: 368 ITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQ 427 ITAG +QIQ V++ L+P LV +L A++KT+KEA WAI+N +SGG + I YLV Sbjct: 361 ITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGG--TVEQIVYLVHC 418 Query: 428 GCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIF 487 G I+PL +LL D +II+V LDA+ NI + E E L+I IE+ GG++KI Sbjct: 419 GIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSI-----MIEECGGLDKIE 473 Query: 488 NCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFGF--GSNVNQQFNF 541 Q++EN+ +Y+ + +IE YF EE+ D+ + P+ F F FNF Sbjct: 474 ALQRHENESVYKASLNLIEKYFSVEEEE-DQNVVPETTSEGFAFQVQDGAPGTFNF 528 >4B8J-A nrPDB Length = 528 Score = 800 bits (2066), Expect = 0.0, Method: Composition-based stats. Identities = 279/528 (52%), Positives = 352/528 (66%), Gaps = 18/528 (3%) Query: 15 EYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESS 74 E RR +K A+E RRRR+ VE+RK++R+E+L K+R A + ++ Sbjct: 12 EVRRNRYKVA--VDAEEGRRRREDNMVEIRKSRREESLLKKRREG---LQAQAPVPASAA 66 Query: 75 VSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPR 134 D++ LP M + SDD QL AT +FR++LS E PPI+ VIQ+GVVPR Sbjct: 67 TGVDKKLE-----SLPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVVPR 121 Query: 135 LVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAI 194 V+F+ LQ EAAWALTNIASGTS TKVV+D AVP+F++LL + S +V+EQA+ Sbjct: 122 FVQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAV 181 Query: 195 WALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN-KPSLIRTATWTLSNLCRGKKPQPDWS 253 WALGNVAGDS RD VL A+ P+L N + K S++R ATWTLSN CRGK PQP + Sbjct: 182 WALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGK-PQPSFE 240 Query: 254 VVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHEST 313 ALP LA+LI+S D E L DACWA+SYLSDG + IQAVI+ + RLVELL H S Sbjct: 241 QTRPALPALARLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSP 300 Query: 314 LVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLS-SPKENIKKEACWTISNITAGN 372 V PALR VGNIVTG+D QTQ +I+ LP L LL+ + K++IKKEACWTISNITAGN Sbjct: 301 SVLIPALRTVGNIVTGDDAQTQCIIDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGN 360 Query: 373 TEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKP 432 +QIQAVI+A +I PLV LL+ AE+ KKEA WAISNA+SGG D I+YLVS+GCIKP Sbjct: 361 KDQIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSH--DQIKYLVSEGCIKP 418 Query: 433 LCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQN 492 LCDLL D RI+ V L+ LENILK+GE DK ++N + I++A G+EKI N Q + Sbjct: 419 LCDLLICPDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIENLQSH 478 Query: 493 ENDKIYEKAYKIIETYFGEEED---AVDETMAPQNAGNTFGFGSNVNQ 537 +N++IYEKA KI+E Y+ +EED APQ A FG G Q Sbjct: 479 DNNEIYEKAVKILEAYWMDEEDDTMGATTVAAPQGATFDFGQGGGAAQ 526 >5TBK-A nrPDB Length = 521 Score = 772 bits (1994), Expect = 0.0, Method: Composition-based stats. Identities = 243/522 (46%), Positives = 324/522 (62%), Gaps = 21/522 (4%) Query: 17 RRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESSVS 76 R NFKNKGR + +RR+R+ VELRK KRDE L KRRN P D ++S + Sbjct: 11 RLKNFKNKGR-DLETMRRQRNEVVVELRKNKRDEHLLKRRNV-PHEDIC-----EDSDID 63 Query: 77 ADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLV 136 D Y L + Q +SD+ QLSA R++LS + PPID +I++G++P LV Sbjct: 64 GD---YRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILV 120 Query: 137 EFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWA 196 + + LQ EAAWALTNIASGTS QT+ VV ++AVPLF++LL++ V EQA+WA Sbjct: 121 HCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWA 180 Query: 197 LGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKP-SLIRTATWTLSNLCRGKKPQPDWSVV 255 LGN+ GD RDYV+ ++P+L + + P + +R TW + NLCR K P P + Sbjct: 181 LGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETI 240 Query: 256 SQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLV 315 + LP L LI+ D LVD WA+SYL+D E IQ VID I LV LLSH+ V Sbjct: 241 QEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKV 300 Query: 316 QTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQ 375 QT ALRAVGNIVTG D QTQVV+N L LL+ PKE I KEA W +SNITAGN +Q Sbjct: 301 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQ 360 Query: 376 IQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCD 435 +QAVIDANL+P ++ LL+ ++ T+KEA WAISN + G R D + YL+ Q I P C+ Sbjct: 361 VQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISG--RKDQVAYLIQQNVIPPFCN 418 Query: 436 LLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNEND 495 LL + D ++++V LD L NILKM E + E G + IE+ GG+EKI Q +EN+ Sbjct: 419 LLTVKDAQVVQVVLDGLSNILKMAEDEAETIG-------NLIEECGGLEKIEQLQNHENE 471 Query: 496 KIYEKAYKIIETYFGEEEDAVDETMAPQNA-GNTFGFGSNVN 536 IY+ AY+II+ +F ++ D ++ P+ G TFGF S+ N Sbjct: 472 DIYKLAYEIIDQFFSSDDIDEDPSLVPEAIQGGTFGFNSSAN 513 >4TNM-A nrPDB Length = 531 Score = 770 bits (1987), Expect = 0.0, Method: Composition-based stats. Identities = 275/532 (51%), Positives = 358/532 (67%), Gaps = 16/532 (3%) Query: 15 EYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESS 74 E RR +K A+E RRRR+ VE+RK KR+E L K+R G+ + + ++ Sbjct: 10 EVRRNRYKVA--VDAEEGRRRREDNLVEIRKNKREENLQKKRFTSSMAFGSATGQTEQDL 67 Query: 75 VSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPR 134 SA+Q L+ LP M + S+D QL AT R++LS E PPI+ V+Q+GVVPR Sbjct: 68 SSANQ-----LKDNLPAMVAGIWSEDSNSQLEATNLLRKLLSIEQNPPINEVVQSGVVPR 122 Query: 135 LVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAI 194 +V+F+ + LQ EAAWALTNIASGTS T V++++ AVP+FIQLL + S +V+EQA+ Sbjct: 123 VVKFLSRDDFPKLQFEAAWALTNIASGTSENTNVIIESGAVPIFIQLLSSASEDVREQAV 182 Query: 195 WALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN-KPSLIRTATWTLSNLCRGKKPQPDWS 253 WALGNVAGDS RD VL AM P+L FN N K S++R ATWTLSN CRGK P P + Sbjct: 183 WALGNVAGDSPKCRDLVLSYGAMTPLLSQFNENTKLSMLRNATWTLSNFCRGK-PPPAFE 241 Query: 254 VVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHEST 313 ALP L +L+ SMD E L DACWA+SYLSD + IQAVI+ + RL++LL H S Sbjct: 242 QTQPALPVLERLVQSMDEEVLTDACWALSYLSDNSNDKIQAVIEAGVVPRLIQLLGHSSP 301 Query: 314 LVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLL-SSPKENIKKEACWTISNITAGN 372 V PALR +GNIVTG+DLQTQ+V++ LP L LL ++ K++IKKEACWTISNITAGN Sbjct: 302 SVLIPALRTIGNIVTGDDLQTQMVLDQQALPCLLNLLKNNYKKSIKKEACWTISNITAGN 361 Query: 373 TEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKP 432 +QIQAVIDA +I LV +L+ AE++ KKEA W ISNA+SGG D I+++VSQGCIKP Sbjct: 362 ADQIQAVIDAGIIQSLVWVLQSAEFEVKKEAAWGISNATSGGTH--DQIKFMVSQGCIKP 419 Query: 433 LCDLLEIADNRIIEVTLDALENILKMGEADKE-ARGLNINENADFIEKAGGMEKIFNCQQ 491 LCDLL D +++ V L+ALENIL +GEA+K N A I++A G+EKI N Q Sbjct: 420 LCDLLTCPDLKVVTVCLEALENILVVGEAEKNLGHTGEDNLYAQMIDEAEGLEKIENLQS 479 Query: 492 NENDKIYEKAYKIIETYFG--EEEDAVDETMAPQNAGNTFGFGSNVNQQFNF 541 ++N+ IY+KA KI+ET++ EE+ DE APQ +G FG + QFNF Sbjct: 480 HDNNDIYDKAVKILETFWTEDNEEEGNDENHAPQ-SGFQFGSTNVPPGQFNF 530 >4B8O-A nrPDB Length = 490 Score = 755 bits (1949), Expect = 0.0, Method: Composition-based stats. Identities = 266/497 (53%), Positives = 334/497 (67%), Gaps = 20/497 (4%) Query: 48 RDEALAK--RRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQL 105 ++ A AK R++ P G D D++ + + + LP M + SDD QL Sbjct: 5 KETAAAKFERQHMDSPDLGTDDDDKAMADIGS----------SLPAMIGGVYSDDNNLQL 54 Query: 106 SATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQ 165 AT +FR++LS E PPI+ VIQ+GVVPR V+F+ LQ EAAWALTNIASGTS Sbjct: 55 EATTQFRKLLSIERSPPIEEVIQSGVVPRFVQFLTREDFPQLQFEAAWALTNIASGTSEN 114 Query: 166 TKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFN 225 TKVV+D AVP+F++LL + S +V+EQA+WALGNVAGDS RD VL A+ P+L N Sbjct: 115 TKVVIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRDLVLANGALLPLLAQLN 174 Query: 226 SN-KPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYL 284 + K S++R ATWTLSN CRGK PQP + ALP LA+LI+S D E L DACWA+SYL Sbjct: 175 EHTKLSMLRNATWTLSNFCRGK-PQPSFEQTRPALPALARLIHSNDEEVLTDACWALSYL 233 Query: 285 SDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLP 344 SDG + IQAVI+ + RLVELL H S V PALR VGNIVTG+D QTQ +I+ LP Sbjct: 234 SDGTNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQCIIDHQALP 293 Query: 345 ALRLLLS-SPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEA 403 L LL+ + K++IKKEACWTISNITAGN +QIQAVI+A +I PLV LL+ AE+ KKEA Sbjct: 294 CLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLLQTAEFDIKKEA 353 Query: 404 CWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADK 463 WAISNA+SGG D I+YLVS+GCIKPLCDLL D RI+ V L+ LENILK+GE DK Sbjct: 354 AWAISNATSGGSH--DQIKYLVSEGCIKPLCDLLICPDIRIVTVCLEGLENILKVGETDK 411 Query: 464 EARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYFGEEED---AVDETM 520 ++N + I++A G+EKI N Q ++N++IYEKA KI+E Y+ +EED Sbjct: 412 TLAAGDVNVFSQMIDEAEGLEKIENLQSHDNNEIYEKAVKILEAYWMDEEDDTMGATTVA 471 Query: 521 APQNAGNTFGFGSNVNQ 537 APQ A FG G Q Sbjct: 472 APQGATFDFGQGGGAAQ 488 >5VQI-B nrPDB Length = 495 Score = 736 bits (1900), Expect = 0.0, Method: Composition-based stats. Identities = 289/472 (61%), Positives = 359/472 (76%), Gaps = 11/472 (2%) Query: 77 ADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLV 136 SQL ++LP+M + + S ++ +Q+ AT KFR++LS+E PPI+ VI+ GVV R V Sbjct: 18 GSHMTESQLSEDLPKMVEGVFSSEIDKQIQATTKFRKLLSKERNPPIEEVIKTGVVGRFV 77 Query: 137 EFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWA 196 EF+R ++Q EAAWALTNIASG++ QT+VV++A AVP+F++LL + +V+EQA+WA Sbjct: 78 EFLRSPH-TLVQFEAAWALTNIASGSATQTQVVIEAGAVPIFVELLGSPEPDVREQAVWA 136 Query: 197 LGNVAGDSTDYRDYVLQCNAMEPILGLF-NSNKPSLIRTATWTLSNLCRGKKPQPDWSVV 255 LGN+AGDS RDYVL C A+ P+L L +S K S++R ATWTLSN CRGK PQPDW+ + Sbjct: 137 LGNIAGDSPQCRDYVLSCGALRPLLTLLGDSRKLSMLRNATWTLSNFCRGKTPQPDWNTI 196 Query: 256 SQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLV 315 + ALP LAKL+YS+D E L+DACWAISYLSDG + IQAVI+ IP+RLVELL H ST V Sbjct: 197 APALPVLAKLVYSLDDEVLIDACWAISYLSDGSNDKIQAVIEAGIPRRLVELLMHASTSV 256 Query: 316 QTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQ 375 QTPALR+VGNIVTG+D+QTQV+IN G LP L LLSS K+ I+KEACWTISNITAGN+ Q Sbjct: 257 QTPALRSVGNIVTGDDVQTQVIINCGALPCLLSLLSSNKDGIRKEACWTISNITAGNSAQ 316 Query: 376 IQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCD 435 IQ+VIDAN+IPPL+ LL A+ KT+KEACWAISNA+SGGLQ+PD IRYLV+QGCIKPLCD Sbjct: 317 IQSVIDANIIPPLIHLLSHADLKTRKEACWAISNATSGGLQKPDQIRYLVAQGCIKPLCD 376 Query: 436 LLEIADNRIIEVTLDALENILKMGEADKEARGL---NINENADFIEKAGGMEKIFNCQQN 492 LL DN+II+V LD LENILK+GE DK A G +IN A FIE+ GGMEKI +CQ N Sbjct: 377 LLACPDNKIIQVALDGLENILKVGELDKNAAGDGPDSINRYALFIEECGGMEKIHDCQTN 436 Query: 493 ENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFGF---GSNVNQQFNF 541 N++IY KAY IIE YF +E++A DE M Q FGF G FNF Sbjct: 437 ANEEIYMKAYNIIEKYFSDEDEAGDEAMGAQ---QQFGFGASGGAQQGGFNF 485 >1UN0-A nrPDB Length = 443 Score = 734 bits (1895), Expect = 0.0, Method: Composition-based stats. Identities = 442/443 (99%), Positives = 442/443 (99%) Query: 88 ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEML 147 ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEML Sbjct: 1 ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEML 60 Query: 148 QLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDY 207 QLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDY Sbjct: 61 QLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDY 120 Query: 208 RDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIY 267 RDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIY Sbjct: 121 RDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIY 180 Query: 268 SMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIV 327 SMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIV Sbjct: 181 SMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIV 240 Query: 328 TGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPP 387 TGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPP Sbjct: 241 TGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPP 300 Query: 388 LVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEV 447 LVKLLEVAE KTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEV Sbjct: 301 LVKLLEVAEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEV 360 Query: 448 TLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIET 507 TLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIET Sbjct: 361 TLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIET 420 Query: 508 YFGEEEDAVDETMAPQNAGNTFG 530 YFGEEEDAVDETMAPQNAGNTFG Sbjct: 421 YFGEEEDAVDETMAPQNAGNTFG 443 >4E4V-A nrPDB Length = 485 Score = 730 bits (1884), Expect = 0.0, Method: Composition-based stats. Identities = 215/471 (45%), Positives = 293/471 (62%), Gaps = 15/471 (3%) Query: 78 DQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVE 137 D + + + + +NS +++ QL AT R++LSRE +PPID +I+AG++P+ V Sbjct: 23 DALNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVS 82 Query: 138 FMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWAL 197 F+ +Q E+AWALTNIASGTS QTK VVD A+P FI LL + + EQA+WAL Sbjct: 83 FLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWAL 142 Query: 198 GNVAGDSTDYRDYVLQCNAMEPILGLF-----NSNKPSLIRTATWTLSNLCRGKKPQPDW 252 GN+AGD + +RD V++ A++P+L L +S +R TWTLSNLCR K P P Sbjct: 143 GNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPI 202 Query: 253 SVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHES 312 V Q LPTL +L++ D E L D CWAISYL+DGP E I V+ + +LV+LL Sbjct: 203 DAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASE 262 Query: 313 TLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGN 372 + TPALRA+GNIVTG D QTQVVI+AG L LL++PK NI+KEA WT+SNITAG Sbjct: 263 LPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGR 322 Query: 373 TEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKP 432 +QIQ V++ L+P LV +L A++KT+KEA WA++N +SGG + I YLV G I+P Sbjct: 323 QDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGG--TVEQIVYLVHCGIIEP 380 Query: 433 LCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQN 492 L +LL D +II V LDA+ NI + E E L+I IE+ GG++KI Q + Sbjct: 381 LMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSI-----MIEECGGLDKIEALQNH 435 Query: 493 ENDKIYEKAYKIIETYFGEEEDAVDETMAPQNA--GNTFGFGSNVNQQFNF 541 EN+ +Y + +IE YF EE+ D+ + P+ G TF FNF Sbjct: 436 ENESVYRASLSLIEKYFSVEEEE-DQNVVPETTSEGYTFQVQDGAPGTFNF 485 >1IAL-A nrPDB Length = 453 Score = 724 bits (1870), Expect = 0.0, Method: Composition-based stats. Identities = 212/466 (45%), Positives = 298/466 (63%), Gaps = 18/466 (3%) Query: 49 DEALAKRRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSAT 108 DE + KRRN D A S ++ ++ + + + + +NS++++ QL AT Sbjct: 1 DEQMLKRRNVSSFPDDATSPLQE------NRNNQGTVNWSVEDIVKGINSNNLESQLQAT 54 Query: 109 VKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKV 168 R++LSRE +PPID +I+AG++P+ V F+ + +Q E+AWALTNIASGTS QTK Sbjct: 55 QAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKA 114 Query: 169 VVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLF---- 224 VVD A+P FI LL + + EQA+WALGN+AGD + +RD V++ A++P+L L Sbjct: 115 VVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPD 174 Query: 225 -NSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISY 283 ++ +R TWTLSNLCR K P P V Q LPTL +L++ D E L D+CWAISY Sbjct: 175 LSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISY 234 Query: 284 LSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVL 343 L+DGP E I+ V+ + +LV+LL + TPALRA+GNIVTG D QTQ VI+AG L Sbjct: 235 LTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGAL 294 Query: 344 PALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEA 403 LL++PK NI+KEA WT+SNITAG +QIQ V++ L+P LV +L A++KT+KEA Sbjct: 295 AVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEA 354 Query: 404 CWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADK 463 WAI+N +SGG + I YLV G I+PL +LL D +II+V LDA+ NI + E Sbjct: 355 AWAITNYTSGG--TVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLG 412 Query: 464 EARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYF 509 E L+I IE+ GG++KI Q++EN+ +Y+ + +IE YF Sbjct: 413 ETEKLSI-----MIEECGGLDKIEALQRHENESVYKASLNLIEKYF 453 >4UAD-A nrPDB Length = 479 Score = 723 bits (1865), Expect = 0.0, Method: Composition-based stats. Identities = 252/446 (56%), Positives = 330/446 (73%), Gaps = 8/446 (1%) Query: 91 QMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAG-VVPRLVEFMRENQPEMLQL 149 +M + L SDD QL+ T KFR++LS+E PPID VI VV R VEF++ N+ LQ Sbjct: 27 EMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQF 86 Query: 150 EAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRD 209 EAAWALTNIASGTS QTK+V++A AVP+FI+LL + +V+EQA+WALGN+AGDS+ RD Sbjct: 87 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRD 146 Query: 210 YVLQCNAMEPILGLFN-SNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYS 268 YVL C+ + P+L L S + ++ R A W LSNLCRGK P P+++ VS LP L++L++S Sbjct: 147 YVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFS 206 Query: 269 MDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVT 328 D++ L DACWA+SYLSDGP E IQAVID + +RLVELL H V +PALRAVGNIVT Sbjct: 207 SDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVT 266 Query: 329 GNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPL 388 G+D+QTQV++N LP L LLSSPKE+I+KEACWTISNITAGN QIQAVIDAN+ P L Sbjct: 267 GDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVL 326 Query: 389 VKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVT 448 +++L+ AE++T+KEA WAI+NA+SGG P+ IRYLVS GCIKPLCDLL + D++I++V Sbjct: 327 IEILQKAEFRTRKEAAWAITNATSGG--TPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVA 384 Query: 449 LDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETY 508 L+ LENIL++GE + + G +N IE+A G++KI Q +EN +IY+KA+ +IE Y Sbjct: 385 LNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHY 444 Query: 509 FGEEEDAVDETMAPQ--NAGNTFGFG 532 FG E+D D ++APQ F F Sbjct: 445 FGVEDD--DSSLAPQVDETQQQFIFQ 468 >6BVV-A nrPDB Length = 459 Score = 710 bits (1832), Expect = 0.0, Method: Composition-based stats. Identities = 214/457 (46%), Positives = 288/457 (63%), Gaps = 11/457 (2%) Query: 82 YSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRE 141 Y L + Q +SD+ QLSA R++LS + PPID +I++G++P LV + Sbjct: 4 YRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLER 63 Query: 142 NQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVA 201 + LQ EAAWALTNIASGTS QT+ VV ++AVPLF++LL++ V EQA+WALGN+ Sbjct: 64 DDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNII 123 Query: 202 GDSTDYRDYVLQCNAMEPILGLFNSNKP-SLIRTATWTLSNLCRGKKPQPDWSVVSQALP 260 GD RDYV+ ++P+L + + P + +R TW + NLCR K P P + + LP Sbjct: 124 GDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILP 183 Query: 261 TLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPAL 320 L LI+ D LVD WA+SYL+D E IQ VID I LV LLSH+ VQT AL Sbjct: 184 ALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAAL 243 Query: 321 RAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVI 380 RAVGNIVTG D QTQVV+N L LL+ PKE I KEA W +SNITAGN +Q+QAVI Sbjct: 244 RAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVI 303 Query: 381 DANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIA 440 DANL+P ++ LL+ ++ T+KEA WAISN + G R D + YL+ Q I P C+LL + Sbjct: 304 DANLVPMIIHLLDKGDFGTQKEAAWAISNLTISG--RKDQVAYLIQQNVIPPFCNLLTVK 361 Query: 441 DNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEK 500 D ++++V LD L NILKM E + E G + IE+ GG+EKI Q +EN+ IY+ Sbjct: 362 DAQVVQVVLDGLSNILKMAEDEAETIG-------NLIEECGGLEKIEQLQNHENEDIYKL 414 Query: 501 AYKIIETYFGEEEDAVDETMAPQNA-GNTFGFGSNVN 536 AY+II+ +F ++ D ++ P+ G TFGF S+ N Sbjct: 415 AYEIIDQFFSSDDIDEDPSLVPEAIQGGTFGFNSSAN 451 >3TJ3-A nrPDB Length = 447 Score = 687 bits (1773), Expect = 0.0, Method: Composition-based stats. Identities = 238/428 (55%), Positives = 314/428 (73%), Gaps = 4/428 (0%) Query: 91 QMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQA-GVVPRLVEFMRENQPEMLQL 149 M + + S ++QLSAT KFR++LS+E PPID VI GVV R VEF++ + LQ Sbjct: 21 DMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQF 80 Query: 150 EAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRD 209 E+AW LTNIASG S QT++V+ A AVP+FI+LL + +V+EQA+WALGN+AGDST RD Sbjct: 81 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD 140 Query: 210 YVLQCNAMEPILGLFNS-NKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYS 268 YVL CN + P+L LF+ N+ ++ R A W LSNLCRGK P P+++ VS L L+ L++ Sbjct: 141 YVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFV 200 Query: 269 MDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVT 328 DT+ L DACWA+SYLSDGP + IQAVID + +RLVELL H V +PALRAVGNIVT Sbjct: 201 SDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVT 260 Query: 329 GNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPL 388 G+D+QTQV++N L +L LLSSPKE+IKKEACWTISNITAGN QIQ VIDAN+ P L Sbjct: 261 GDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPAL 320 Query: 389 VKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVT 448 + +L+ AE++T+KEA WAI+NA+SGG + I+YLV GCIKPLCDLL + D++I++V Sbjct: 321 ISILQTAEFRTRKEAAWAITNATSGGS--AEQIKYLVELGCIKPLCDLLTVMDSKIVQVA 378 Query: 449 LDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETY 508 L+ LENIL++GE + + G IN IE+A G++KI Q +EN +IY+KA+ +IE Y Sbjct: 379 LNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHY 438 Query: 509 FGEEEDAV 516 FG E++ Sbjct: 439 FGTEDEDS 446 >2Z6G-A nrPDB Length = 780 Score = 59.3 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 77/408 (18%), Positives = 139/408 (34%), Gaps = 77/408 (18%) Query: 88 ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEML 147 +P++T+ LN +D A V Q+ +E ++++ P++V + Sbjct: 151 AIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASR--HAIMRS---PQMVSAIVRTMQNTN 205 Query: 148 QLEAAWALTNIASGTSAQTK-------VVVDADAVPLFIQLLYTGSVEVKEQAIWALGNV 200 +E A SGT + + +P + +L + V AI L N+ Sbjct: 206 DVETA----RCTSGTLHNLSHHREGLLAIFKSGGIPALVNMLGSPVDSVLFHAITTLHNL 261 Query: 201 AGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTAT-----------------------W 237 + V ++ ++ L N + T Sbjct: 262 LLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQ 321 Query: 238 TLSNLCRGKKPQPDWSVVSQALPTLAKL-----------------IYSMDT-ETLVDAC- 278 L N+ R + S+ L L+ ++ D + LV C Sbjct: 322 ALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCL 381 Query: 279 WAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVI 338 W + LSD + + LV+LL + V T A + N+ N +V Sbjct: 382 WTLRNLSDAATKQEGM---EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVC 438 Query: 339 NAGVLPAL--RLLLSSPKENIKKEACWTISNITAGNTE---QIQAVIDANLIPPLVKLLE 393 G + AL +L + +E+I + A + ++T+ + + AV +P +VKLL Sbjct: 439 QVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQDAEMAQNAVRLHYGLPVVVKLL- 497 Query: 394 VAEYKTKKEACWAISNASSGGLQR----PDIIRYLVSQGCIKPLCDLL 437 + W + A+ G ++ P L QG I L LL Sbjct: 498 ------HPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 539 Score = 35.8 bits (81), Expect = 0.050, Method: Composition-based stats. Identities = 33/171 (19%), Positives = 59/171 (34%), Gaps = 25/171 (14%) Query: 55 RRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKF-RQ 113 R + P A + Q +L LP + + L+ + ATV R Sbjct: 456 REDITEPAICALRHLTSRHQDAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRN 515 Query: 114 I-LSREHRPPIDVVIQAGVVPRLVEFMRENQPEML----------QLEAAWALTNIASGT 162 + L + P+ G +PRLV+ + + Q + I Sbjct: 516 LALCPANHAPLRE---QGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEAC 572 Query: 163 SA---------QTKVVVDA-DAVPLFIQLLYTGSVEVKEQAIWALGNVAGD 203 + ++V+ + +PLF+QLLY+ ++ A L +A D Sbjct: 573 TGALHILARDIHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQD 623 Score = 28.5 bits (62), Expect = 7.1, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 57/157 (36%), Gaps = 12/157 (7%) Query: 57 NFIPPTDGADSDEEDESSVSADQQFYSQLQQ--ELPQMTQQLNSDDMQEQLSATVKFRQI 114 N P + + V A Q + Q + + M+E + A I Sbjct: 522 NHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGV---RMEEIVEACTGALHI 578 Query: 115 LSREHRPPIDVVIQA-GVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDAD 173 L+R+ I VI+ +P V+ + E +Q AA L +A A + + Sbjct: 579 LARDIHNRI--VIRGLNTIPLFVQLLYSP-IENIQRVAAGVLCELAQDKEAAEAIEAEGA 635 Query: 174 AVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDY 210 PL +LL++ + V A L ++ D DY Sbjct: 636 TAPL-TELLHSRNEGVATYAAAVLFRMSEDKPQ--DY 669 >2GL7-A nrPDB Length = 550 Score = 59.0 bits (141), Expect = 6e-09, Method: Composition-based stats. Identities = 80/417 (19%), Positives = 146/417 (35%), Gaps = 65/417 (15%) Query: 73 SSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAG-V 131 S++ +Q + +P++T+ LN +D A V Q+ +E ++++ + Sbjct: 1 SNLINEQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASR--HAIMRSPQM 58 Query: 132 VPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKE 191 V +V M+ A L N+ S + + +P +++L + V Sbjct: 59 VSAIVRTMQNTNDVETARCTAGTLHNL-SHHREGLLAIFKSGGIPALVKMLGSPVDSVLF 117 Query: 192 QAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTAT--------------- 236 AI L N+ + V ++ ++ L N + T Sbjct: 118 YAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKL 177 Query: 237 --------WTLSNLCRGKKPQPDWSVVSQALPTLAKL-----------------IYSMDT 271 L N+ R + S+ L L+ ++ D Sbjct: 178 IILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDP 237 Query: 272 -ETLVDAC-WAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTG 329 + LV C W + LSD + + LV+LL + V T A + N+ Sbjct: 238 SQRLVQNCLWTLRNLSDAATKQEGM---EGLLGTLVQLLGSDDINVVTCAAGILSNLTCN 294 Query: 330 NDLQTQVVINAGVLPAL--RLLLSSPKENIKKEACWTISNITAGNTE---QIQAVIDANL 384 N +V G + AL +L + +E+I + A + ++T+ + E AV Sbjct: 295 NYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYG 354 Query: 385 IPPLVKLLEVAEYKTKKEACWAISNASSGGLQR----PDIIRYLVSQGCIKPLCDLL 437 +P +VKLL + W + A+ G ++ P L QG I L LL Sbjct: 355 LPVVVKLL-------HPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 404 Score = 38.5 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 34/171 (19%), Positives = 60/171 (35%), Gaps = 25/171 (14%) Query: 55 RRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKF-RQ 113 R + P A + Q +L LP + + L+ + ATV R Sbjct: 321 REDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRN 380 Query: 114 I-LSREHRPPIDVVIQAGVVPRLVEFMRENQPEML----------QLEAAWALTNIASGT 162 + L + P+ G +PRLV+ + + Q + I G Sbjct: 381 LALCPANHAPLRE---QGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGC 437 Query: 163 S---------AQTKVVVDA-DAVPLFIQLLYTGSVEVKEQAIWALGNVAGD 203 + ++V+ + +PLF+QLLY+ ++ A L +A D Sbjct: 438 TGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQD 488 >2Z6H-A nrPDB Length = 644 Score = 58.6 bits (140), Expect = 7e-09, Method: Composition-based stats. Identities = 78/402 (19%), Positives = 140/402 (34%), Gaps = 65/402 (16%) Query: 88 ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAG-VVPRLVEFMRENQPEM 146 +P++T+ LN +D A V Q+ +E ++++ +V +V M+ Sbjct: 15 AIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASR--HAIMRSPQMVSAIVRTMQNTNDVE 72 Query: 147 LQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTD 206 A L N+ S + + +P +++L + V AI L N+ Sbjct: 73 TARCTAGTLHNL-SHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEG 131 Query: 207 YRDYVLQCNAMEPILGLFNSNKPSLIRTAT-----------------------WTLSNLC 243 + V ++ ++ L N + T L N+ Sbjct: 132 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIM 191 Query: 244 RGKKPQPDWSVVSQALPTLAKL-----------------IYSMDT-ETLVDAC-WAISYL 284 R + S+ L L+ ++ D + LV C W + L Sbjct: 192 RTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNL 251 Query: 285 SDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLP 344 SD + + LV+LL + V T A + N+ N +V G + Sbjct: 252 SDAATKQEGM---EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIE 308 Query: 345 AL--RLLLSSPKENIKKEACWTISNITAGNTE---QIQAVIDANLIPPLVKLLEVAEYKT 399 AL +L + +E+I + A + ++T+ + E AV +P +VKLL Sbjct: 309 ALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLL------- 361 Query: 400 KKEACWAISNASSGGLQR----PDIIRYLVSQGCIKPLCDLL 437 + W + A+ G ++ P L QG I L LL Sbjct: 362 HPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 403 Score = 38.5 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 34/171 (19%), Positives = 60/171 (35%), Gaps = 25/171 (14%) Query: 55 RRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKF-RQ 113 R + P A + Q +L LP + + L+ + ATV R Sbjct: 320 REDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRN 379 Query: 114 I-LSREHRPPIDVVIQAGVVPRLVEFMRENQPEML----------QLEAAWALTNIASGT 162 + L + P+ G +PRLV+ + + Q + I G Sbjct: 380 LALCPANHAPLRE---QGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGC 436 Query: 163 S---------AQTKVVVDA-DAVPLFIQLLYTGSVEVKEQAIWALGNVAGD 203 + ++V+ + +PLF+QLLY+ ++ A L +A D Sbjct: 437 TGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQD 487 >4R10-A nrPDB Length = 572 Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 77/413 (18%), Positives = 138/413 (33%), Gaps = 40/413 (9%) Query: 64 GADSDEEDESSVSADQQFYSQLQQ----ELPQMTQQLNSDDMQEQLSATVKFRQILSREH 119 G + D Y LP + + + D A + + + Sbjct: 2 GIQMPTQQLKQSVMDLLTYEGSNDMSGLSLPDLVKLMCDHDESVVARAVHRAYMLSREDP 61 Query: 120 R----PPIDVVIQAGVVPRLVEFM---RENQPEMLQLEAAWALTNIASGTSAQTK---VV 169 P D VE + ++ ++ A AL+++ S Q ++ Sbjct: 62 NFFNAPGFDH-------RSFVEALMAASKSSNVNVRRNAIGALSHM----SEQRGGPLLI 110 Query: 170 VDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKP 229 + + I++LY V A+ L N+ +D R NA+E + + P Sbjct: 111 FRSGGLAEIIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQARALNAVEALTPHLHKTNP 170 Query: 230 SLIRTATWTLSNLCRGKKPQPD--WSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDG 287 L+ L L P S++ + YS + + I LS Sbjct: 171 KLLAQVADGLYFLLIDDAPSKITFLSLLGPQILVSILREYSDHRKLIYTVVRCIRSLSVC 230 Query: 288 PQEAIQAVIDVRIPKRL-VELLSHESTLVQTP---ALRAVGNIVTGNDLQTQVVINAGVL 343 P A+I + L VEL + + QT A+R + + T + TQ++I Sbjct: 231 PSNK-PALISLGCLPALYVELCTAKDERSQTAILVAMRNLSDSATNEENLTQLIIK---- 285 Query: 344 PALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAE--YKTKK 401 L ++ + + AC T+SN+T NT Q V I LV + + + Sbjct: 286 --LLEIIRVANDGMTACACGTLSNLTCNNTRNKQTVCSHGGIDALVTAIRRLPEVEEVTE 343 Query: 402 EACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALEN 454 A A+ + ++ + L + D LE +I+ L + N Sbjct: 344 PALCALRHCTARHSLAEEAQSELRFCQAFPVILDQLETLRTPVIKAALGVIRN 396 >3IFQ-A nrPDB Length = 553 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 65/333 (19%), Positives = 129/333 (38%), Gaps = 19/333 (5%) Query: 88 ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVV--PRLVEFMRENQPE 145 LP++T+ LN +D A + Q+ +E + ++ P+LV + Sbjct: 20 ALPELTKLLNDEDPVVVTKAAMIVNQLSKKEAS-------RRALMGSPQLVAAVVRTMQN 72 Query: 146 MLQLEAAWALTNIASGTSAQTK---VVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAG 202 L+ A T+I S + + + +P +++L + V AI L N+ Sbjct: 73 TSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLL 132 Query: 203 DSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTL 262 + V + ++ ++ L N N P + T L L G + + + L Sbjct: 133 YQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQAL 192 Query: 263 AKLIYSMDTE-TLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALR 321 +++ + E L + LS P A+++ + L + L+ S + L Sbjct: 193 VQIMRNYSYEKLLWTTSRVLKVLSVCPSNK-PAIVEAGGMQALGKHLTSNSPRLVQNCLW 251 Query: 322 AVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVID 381 + N+ +D+ T+ VL L LS N+ A T+SN+T N++ V Sbjct: 252 TLRNL---SDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQ 308 Query: 382 ANLIPPLVK-LLEVAE-YKTKKEACWAISNASS 412 + + L+ +L + + A A+ + +S Sbjct: 309 NSGVEALIHAILRAGDKDDITEPAVCALRHLTS 341 Score = 48.9 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 41/198 (20%), Positives = 75/198 (37%), Gaps = 41/198 (20%) Query: 80 QFYSQLQQELPQMTQQLNSDDMQEQLSATVKF-RQI-LSREHRPPIDVVIQAGVVPRLVE 137 Q +L +P + + LN + + AT+ R + L + P+ A V+PRLV+ Sbjct: 350 QNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQE---AAVIPRLVQ 406 Query: 138 FMRENQPEMLQLEAAWALTNIASGTSA------QTKVVVDA------------------- 172 + + + A ++A+GT + + +V+ Sbjct: 407 LLVKAHQD--------AQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIF 458 Query: 173 --DAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPS 230 + +PLF+QLLY+ ++ A L +A D D + A P++ L +S Sbjct: 459 RLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAA-DAIDAEGASAPLMELLHSRNEG 517 Query: 231 LIRTATWTLSNLCRGKKP 248 A L + K P Sbjct: 518 TATYAAAVLFRISEDKNP 535 >5ZHX-A nrPDB Length = 487 Score = 55.9 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 58/336 (17%), Positives = 121/336 (36%), Gaps = 33/336 (9%) Query: 170 VDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLF----- 224 VDA + +QLL + EV Q ALGN+ DS + ++ + ++ L Sbjct: 15 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQ 74 Query: 225 NSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYL 284 N+ + A L+ L K+ ++ + + K I E + + ++ L Sbjct: 75 NAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFE---VLAPL 131 Query: 285 SDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGN---------DLQTQ 335 ++ +Q V + + + L+E++ V + + + TG+ D Q Sbjct: 132 AENDAIKLQLV-EAGLVECLLEIV---QQKVDSDKEDDITELKTGSDLMVLLLLGDESMQ 187 Query: 336 VVINAGVLPALRLLLS---SPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLL 392 + G + +LS S ++ I+N A N ++D ++ L+ LL Sbjct: 188 KLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANF-ARNDANCIHMVDNGIVEKLMDLL 246 Query: 393 EV----AEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVT 448 + + A A+ N + + + ++S G + + L+ + Sbjct: 247 DRHVEDGNVTVQHAALSALRNLAIPVINKAK----MLSAGVTEAVLKFLKSEMPPVQFKL 302 Query: 449 LDALENILKMGEADKEARGLNINENADFIEKAGGME 484 L L ++ E G N+ +E + Sbjct: 303 LGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKD 338 >3L6X-A nrPDB Length = 584 Score = 48.9 bits (115), Expect = 6e-06, Method: Composition-based stats. Identities = 35/155 (22%), Positives = 71/155 (45%), Gaps = 7/155 (4%) Query: 233 RTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAI 292 R + +L +L +G P P+W LP + ++ +A + +L + + Sbjct: 26 RGSLASLDSLRKGGPPPPNWR--QPELPEVIAMLGFRLDAVKSNAAAYLQHLC-YRNDKV 82 Query: 293 QA-VIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVI-NAGVLPALRLLL 350 + V ++ LV LL H V A A+ NI G D ++ I N +PAL LL Sbjct: 83 KTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLL 142 Query: 351 SSPKE-NIKKEACWTISNITAGNTEQIQAVIDANL 384 ++ ++ + T+ N+++ ++ +++ ++D L Sbjct: 143 RKARDMDLTEVITGTLWNLSSHDSIKME-IVDHAL 176 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 5/136 (3%) Query: 302 KRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEA 361 ++ +L V++ A + ++ ND V +P L LL PK+ + A Sbjct: 51 PEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGA 110 Query: 362 CWTISNITAGN-TEQIQAVIDANLIPPLVKLLEVAEYKTKKEAC----WAISNASSGGLQ 416 C + NI+ G + A+ + + +P LV+LL A E W +S+ S ++ Sbjct: 111 CGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKME 170 Query: 417 RPDIIRYLVSQGCIKP 432 D + ++ I P Sbjct: 171 IVDHALHALTDEVIIP 186 >2QNA-A nrPDB Length = 762 Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 49/128 (38%), Gaps = 6/128 (4%) Query: 297 DVRIPKRLVELLS----HESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSS 352 + I ++ + + + A+ A G I+ G + + +P L L+ Sbjct: 235 EDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKD 294 Query: 353 PKENIKKEACWTISNITA-GNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNAS 411 P ++ A WT+ I I V A L+ L++ L AE + CWA S+ + Sbjct: 295 PSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLS-AEPRVASNVCWAFSSLA 353 Query: 412 SGGLQRPD 419 + D Sbjct: 354 EAAYEAAD 361 Score = 36.2 bits (82), Expect = 0.032, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 13/120 (10%) Query: 131 VVPRLVEFMREN-QPEMLQLE--AAWALTNIASGT--SAQTKVVVDADAVPLFIQLLYTG 185 +VP ++ F++E+ + + A A I G S +V+ A+P I+L+ Sbjct: 238 IVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQ--AMPTLIELMKDP 295 Query: 186 SVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFN---SNKPSLIRTATWTLSNL 242 SV V++ A W +G + + + + P+L S +P + W S+L Sbjct: 296 SVVVRDTAAWTVGRICELLP---EAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSL 352 >2Q5D-A nrPDB Length = 876 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 49/128 (38%), Gaps = 6/128 (4%) Query: 297 DVRIPKRLVELLS----HESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSS 352 + I ++ + + + A+ A G I+ G + + +P L L+ Sbjct: 360 EDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKD 419 Query: 353 PKENIKKEACWTISNITA-GNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNAS 411 P ++ A WT+ I I V A L+ L++ L AE + CWA S+ + Sbjct: 420 PSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLS-AEPRVASNVCWAFSSLA 478 Query: 412 SGGLQRPD 419 + D Sbjct: 479 EAAYEAAD 486 Score = 36.2 bits (82), Expect = 0.041, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 13/120 (10%) Query: 131 VVPRLVEFMREN-QPEMLQLE--AAWALTNIASGT--SAQTKVVVDADAVPLFIQLLYTG 185 +VP ++ F++E+ + + A A I G S +V+ A+P I+L+ Sbjct: 363 IVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQ--AMPTLIELMKDP 420 Query: 186 SVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFN---SNKPSLIRTATWTLSNL 242 SV V++ A W +G + + + + P+L S +P + W S+L Sbjct: 421 SVVVRDTAAWTVGRICELLP---EAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSL 477 >1M5N-S nrPDB Length = 485 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 46/119 (38%), Gaps = 6/119 (5%) Query: 297 DVRIPKRLVELLS----HESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSS 352 + I ++ + + + A+ A G I+ G + + +P L L+ Sbjct: 360 EDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKD 419 Query: 353 PKENIKKEACWTISNITA-GNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNA 410 P ++ A WT+ I I V A L+ L++ L AE + CWA S+ Sbjct: 420 PSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLS-AEPRVASNVCWAFSSL 477 Score = 35.5 bits (80), Expect = 0.064, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 13/120 (10%) Query: 131 VVPRLVEFMREN-QPEMLQLE--AAWALTNIASGT--SAQTKVVVDADAVPLFIQLLYTG 185 +VP ++ F++E+ + + A A I G S +V+ A+P I+L+ Sbjct: 363 IVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQ--AMPTLIELMKDP 420 Query: 186 SVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFN---SNKPSLIRTATWTLSNL 242 SV V++ A W +G + + + + P+L S +P + W S+L Sbjct: 421 SVVVRDTAAWTVGRICELLP---EAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSL 477 >2OT8-A nrPDB Length = 852 Score = 37.0 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 5/114 (4%) Query: 175 VPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQC-NAMEPILGLFNSNKPSLIR 233 +PL +LL+ VKE I LG +A ++ + P L S+K +L+R Sbjct: 361 LPLLKELLFHHEWVVKESGILVLGAIA---EGCMQGMIPYLPELIPHLIQCLSDKKALVR 417 Query: 234 TAT-WTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSD 286 + T WTLS QP + + + L K I + AC A + L + Sbjct: 418 SITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEE 471 Score = 35.5 bits (80), Expect = 0.067, Method: Composition-based stats. Identities = 58/367 (15%), Positives = 119/367 (32%), Gaps = 87/367 (23%) Query: 131 VVPRLVEFMRENQPEMLQLEAAW-ALTNIASGTSAQTKVVVDADA--------VPLFIQL 181 ++P+L + E A+ AL I ++ ++D+D +P F+Q Sbjct: 129 LLPKLCSLLDSEDYNTC--EGAFGALQKICEDSAE----ILDSDVLDRPLNIMIPKFLQF 182 Query: 182 LYTGSVEVKEQAIWALGN----------------------VAGDS-TDYRDYVLQCNAME 218 S +++ A+ + +AGD + R V C A+ Sbjct: 183 FKHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEPEVRKNV--CRALV 240 Query: 219 PILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVS--------------------QA 258 +L + + + + + + Sbjct: 241 MLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKL 300 Query: 259 LPTLAKLIYSMDTETLV------------DAC--WAISYLSDGPQEAIQAVIDVRIPKRL 304 +P L + D + ++ D W + S + + V + + Sbjct: 301 IPVLVNGMKYSDIDIILLKGDVEGGSGGDDTISDWNLRKCSAAALDVLANVYRDELLPHI 360 Query: 305 V----ELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKE 360 + ELL H +V+ + +G I G +Q + ++P L LS K ++ Sbjct: 361 LPLLKELLFHHEWVVKESGILVLGAIAEGC-MQGMIPYLPELIPHLIQCLSDKKALVRSI 419 Query: 361 ACWTISNITAGNTEQIQAVIDANLIPPLVKLLEV---AEYKTKKEACWAISNASSGGLQR 417 CWT+S + D L P + +LL+ + + ++ AC A A+ Sbjct: 420 TCWTLSRYA---HWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAF--ATLEEEAC 474 Query: 418 PDIIRYL 424 +++ YL Sbjct: 475 TELVPYL 481 >3SL9-A nrPDB Length = 167 Score = 37.0 bits (84), Expect = 0.020, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 61/159 (38%), Gaps = 5/159 (3%) Query: 76 SADQQFYSQLQQ-ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAG-VVP 133 ++ Q ++L +P++T+ LN +D A V Q+ +E ++++ +V Sbjct: 1 GSNYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASR--HAIMRSPQMVS 58 Query: 134 RLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQA 193 +V M+ A L N+ S + + +P +++L + V A Sbjct: 59 AIVRTMQNTNDVETARCTAGTLHNL-SHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYA 117 Query: 194 IWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLI 232 I L N+ + V ++ ++ L N + Sbjct: 118 ITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFL 156 >1OYZ-A nrPDB Length = 280 Score = 36.6 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 31/132 (23%), Positives = 52/132 (39%), Gaps = 10/132 (7%) Query: 156 TNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCN 215 TN+ T+ V+ D +PL I LL + +V+ A +A+ D++D RD ++ Sbjct: 142 TNVRRATAFAISVINDKATIPLLINLLKDPNGDVRNWAAFAININKYDNSDIRDCFVEML 201 Query: 216 AMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQA---------LPTLAKLI 266 + + R LS LC K + + +A LP L ++ Sbjct: 202 QDKNEEVRIEAIIGLSYRKDKRVLSVLCDELKKNTVYDDIIEAAGELGDKTLLPVLDTML 261 Query: 267 YS-MDTETLVDA 277 Y D E + A Sbjct: 262 YKFDDNEIITSA 273 >4XRI-A nrPDB Length = 882 Score = 35.8 bits (81), Expect = 0.047, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 53/146 (36%), Gaps = 9/146 (6%) Query: 255 VSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAI-QAVIDVRIPKRLVELLSHEST 313 + + + + D A A + DGP+E + + ++ + L+ ++ ES Sbjct: 374 IPPVIQFVEHNLRHADWHFRDAAVSAFGAIMDGPEEKVLEPIVKTGMQP-LIAMMEDESI 432 Query: 314 LVQTPALRAVGNIVTGNDLQTQVVINAGVL--PALRLLLSSPKENIKKEACWTISNIT-- 369 V+ A+G I + L L++SPK + CW + NI Sbjct: 433 QVRDSTAYALGRITEACSEAIDPNTHLEPLIRSLFNGLMNSPK--MAASCCWALMNIAER 490 Query: 370 -AGNTEQIQAVIDANLIPPLVKLLEV 394 AG Q + + + LL V Sbjct: 491 FAGEPGAAQNPLTPHFNQSVTNLLTV 516 >4G3A-A nrPDB Length = 237 Score = 35.5 bits (80), Expect = 0.064, Method: Composition-based stats. Identities = 37/181 (20%), Positives = 69/181 (38%), Gaps = 19/181 (10%) Query: 281 ISYLSDGPQEAIQAVIDVR-IPKRLVELLSHESTLVQTPALRAVGNIVT--GNDLQTQVV 337 +++LSD + D+ + L+ L+ + +L A ++ G+D Sbjct: 32 VTFLSDDTNSIV--CTDMGFLIDGLMPWLTGSHFKIAQKSLEAFSELIKRLGSDFNA--- 86 Query: 338 INAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEY 397 A VLP + L ++ ++++A + ++ QA+ID + Sbjct: 87 YTATVLPHVIDRLGDSRDTVREKAQLLLRDLMEHRVLPPQALIDK----LATSCFKHKNA 142 Query: 398 KTKKEACWAISNASSG-GLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENIL 456 K ++E I NA G Q+ + Y I P+C LL + E + L I Sbjct: 143 KVREEFLQTIVNALHEYGTQQLSVRVY------IPPVCALLGDPTVNVREAAIQTLVEIY 196 Query: 457 K 457 K Sbjct: 197 K 197 >5OWU-A nrPDB Length = 861 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 32/173 (18%), Positives = 65/173 (37%), Gaps = 23/173 (13%) Query: 251 DWSVVSQALPTLAKLI--YSMDTETLVDACWAIS---------YLSDGPQEAIQAVIDVR 299 S + +P L L+ + D E D W +S + + ++ V++ Sbjct: 318 ALSSIKDVVPNLLNLLTRQNEDPE---DDDWNVSMSAGACLQLFAQNCGNHILEPVLEF- 373 Query: 300 IPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKK 359 + + ++ ++ + A+ A G+I+ G D + LP++ L++ +K+ Sbjct: 374 ----VEQNITADNWRNREAAVMAFGSIMDGPDKVQRTYYVHQALPSILNLMNDQSLQVKE 429 Query: 360 EACWTISNITAGNTEQI--QAVIDANLIPPLVKLLEVAEYKTKKEACWAISNA 410 W I I E I Q + + L+ L + + T W I N Sbjct: 430 TTAWCIGRIADSVAESIDPQQHLPGVVQACLIGLQDHPKVATN--CSWTIINL 480 Score = 34.3 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 47/116 (40%), Gaps = 5/116 (4%) Query: 131 VVPRLVEFMREN---QPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSV 187 ++ ++EF+ +N + A A +I G + A+P + L+ S+ Sbjct: 366 ILEPVLEFVEQNITADNWRNREAAVMAFGSIMDGPDKVQRTYYVHQALPSILNLMNDQSL 425 Query: 188 EVKEQAIWALGNVAGDSTDYRDYVLQC-NAMEPILGLFNSNKPSLIRTATWTLSNL 242 +VKE W +G +A + D ++ L + P + +WT+ NL Sbjct: 426 QVKETTAWCIGRIADSVAESIDPQQHLPGVVQACLIGLQDH-PKVATNCSWTIINL 480 >1K8C-A nrPDB Length = 322 Score = 32.8 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 8/61 (13%) Query: 362 CWTISNITAGNTEQIQAVIDANLIPPLVKLLEVA-EYKTKKEACWAISNASSGGLQRPDI 420 CW ++N TAG EQ+ I A +L + A +Y +KE + A GL + + Sbjct: 23 CWKLANATAG--EQVYQAIKAGY-----RLFDGAEDYGNEKEVGDGVKRAIDEGLVKREE 75 Query: 421 I 421 I Sbjct: 76 I 76 >3DA4-A nrPDB Length = 279 Score = 32.8 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 24/65 (36%), Gaps = 12/65 (18%) Query: 173 DAVPLFIQLLYT--GSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPS 230 A PL +Q++Y+ S + QA+ T DY+ + A P+ S Sbjct: 32 GAGPLLVQVVYSFFQSPNMCLQAL----------TQLEDYIKKHGASNPLTLQIISTNIG 81 Query: 231 LIRTA 235 A Sbjct: 82 YFCNA 86 >5AVO-A nrPDB Length = 304 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 15/26 (57%) Query: 109 VKFRQILSREHRPPIDVVIQAGVVPR 134 FR++L + P ++ VI G+V R Sbjct: 13 KAFRKLLHEKRSPELNDVIIGGIVTR 38 >5L9W-A nrPDB Length = 684 Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 21/43 (48%), Gaps = 2/43 (4%) Query: 382 ANLIPPLV--KLLEVAEYKTKKEACWAISNASSGGLQRPDIIR 422 +IPPL+ +LE + + W ++A GG+ PD + Sbjct: 87 HAVIPPLIIKYILETYGDEIRDGDLWFANDAVYGGVHNPDQMV 129 >4U15-A nrPDB Length = 418 Score = 30.8 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 21/43 (48%) Query: 195 WALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATW 237 WALGN+A D DYV ++ +L + S+ R T+ Sbjct: 78 WALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTY 120 >4U14-A nrPDB Length = 460 Score = 30.8 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 21/43 (48%) Query: 195 WALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATW 237 WALGN+A D DYV ++ +L + S+ R T+ Sbjct: 78 WALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTY 120 >5DIS-C nrPDB Length = 289 Score = 29.3 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 3/50 (6%) Query: 10 SKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFI 59 S P R + +K+K RRRR +EL+K+KR + + R Sbjct: 22 STAAPHPRLSQYKSKYSSLEQSERRRR---LLELQKSKRLDYVNHARRLA 68 >3NC0-B nrPDB Length = 362 Score = 29.3 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 3/50 (6%) Query: 10 SKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFI 59 S P R + +K+K RRRR +EL+K+KR + + R Sbjct: 22 STAAPHPRLSQYKSKYSSLEQSERRRR---LLELQKSKRLDYVNHARRLA 68 >4V61-AU nrPDB Length = 190 Score = 28.5 bits (62), Expect = 6.8, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 32/82 (39%), Gaps = 7/82 (8%) Query: 14 PEYRR-TNFK---NKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDE 69 PE R F+ + + RRR ++RK K EA + R P A Sbjct: 106 PEERLLNRFRREVMRAGVIQECKRRRFFENTQDVRKRKTREAAKRNRRRRPQ---ARFTP 162 Query: 70 EDESSVSADQQFYSQLQQELPQ 91 +++ V A +Q +LP+ Sbjct: 163 QNKQDVPATKQEADDDNWDLPE 184 >5WVI-Z nrPDB Length = 993 Score = 28.5 bits (62), Expect = 8.5, Method: Composition-based stats. Identities = 15/114 (13%), Positives = 45/114 (39%), Gaps = 7/114 (6%) Query: 47 KRDEALAKRRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLS 106 K+ + + ++ P + ++ + + ++L+ +L + ++L DD + Sbjct: 7 KKQQTIDEQSQISPEKQTPNKKDKKKEEEEQLSEEDAKLKTDLELLVERLKEDDSSLYEA 66 Query: 107 ATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIAS 160 + ++ + VP+ ++F+R P++ + W N+ S Sbjct: 67 SLNALKESIKNSTS-------SMTAVPKPLKFLRPTYPDLCSIYDKWTDPNLKS 113 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.131 0.359 Lambda K H 0.267 0.0407 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,670,277 Number of Sequences: 36641 Number of extensions: 769701 Number of successful extensions: 2916 Number of sequences better than 10.0: 40 Number of HSP's better than 10.0 without gapping: 47 Number of HSP's successfully gapped in prelim test: 31 Number of HSP's that attempted gapping in prelim test: 2151 Number of HSP's gapped (non-prelim): 138 length of query: 542 length of database: 10,336,785 effective HSP length: 102 effective length of query: 440 effective length of database: 6,599,403 effective search space: 2903737320 effective search space used: 2903737320 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 61 (28.1 bits)