BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q02046 (320 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1EDZ-A nrPDB 660 0.0 5O2A-B nrPDB 91 5e-19 4A5O-A nrPDB 88 6e-18 6DEB-A nrPDB 87 1e-17 5NHS-A nrPDB 82 3e-16 3L07-A nrPDB 77 1e-14 4CJX-A nrPDB 76 2e-14 4A26-A nrPDB 75 5e-14 5TC4-A nrPDB 73 2e-13 5ZF1-A nrPDB 69 2e-12 6APE-A nrPDB 68 6e-12 1DIA-A nrPDB 61 8e-10 2C2Y-A nrPDB 54 1e-07 4B4V-A nrPDB 53 2e-07 3NGX-A nrPDB 50 1e-06 3RWB-A nrPDB 37 0.009 5Y3K-A nrPDB 33 0.16 2X6Q-A nrPDB 30 1.1 3U4C-A nrPDB 30 1.2 3OEC-A nrPDB 30 1.4 5M6C-E nrPDB 30 1.7 5MRJ-A nrPDB 30 1.7 4FXY-P nrPDB 30 2.0 5LV0-A nrPDB 30 2.0 2DPD-A nrPDB 29 2.3 6IB8-A nrPDB 29 2.4 3WOH-A nrPDB 28 3.7 1LU9-A nrPDB 28 4.1 2BDQ-A nrPDB 28 6.0 4E6P-A nrPDB 28 7.1 1C7O-A nrPDB 28 7.8 1HXH-A nrPDB 27 8.1 1Y23-A nrPDB 27 9.0 3F3S-A nrPDB 27 9.6 >1EDZ-A nrPDB Length = 320 Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/320 (100%), Positives = 320/320 (100%) Query: 1 MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKT 60 MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKT Sbjct: 1 MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKT 60 Query: 61 SESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDV 120 SESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDV Sbjct: 61 SESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDV 120 Query: 121 EGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKC 180 EGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKC Sbjct: 121 EGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKC 180 Query: 181 IVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLK 240 IVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLK Sbjct: 181 IVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLK 240 Query: 241 KCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTI 300 KCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTI Sbjct: 241 KCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTI 300 Query: 301 AMLLRNMLRLVRNVELSKEK 320 AMLLRNMLRLVRNVELSKEK Sbjct: 301 AMLLRNMLRLVRNVELSKEK 320 >5O2A-B nrPDB Length = 289 Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 82/319 (25%), Positives = 140/319 (43%), Gaps = 60/319 (18%) Query: 6 RTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMG 65 + I +A+ +E+ V+ + + P L L ++PA+++Y +K E +G Sbjct: 5 KIIDGKTIAQQVRSEVAQKVQA-RIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVG 63 Query: 66 F---RYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEG 122 F YDL + L E I N D++++GI+V+ P+ + + + + +KDV+G Sbjct: 64 FVSRSYDLPETTSEAELLELIDTLNADNTIDGILVHLPLPAGIDNVKVLERIHPDKDVDG 123 Query: 123 LNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIV 182 + Y+ R + RL+ PCTP IV +LE I +G +V Sbjct: 124 FHP------YNVGRLCQRAPRLR---PCTPRGIVTLLERYNIDT---------FGLNAVV 165 Query: 183 INRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKC 242 I S IVGRP++ L G T +FT+ +HHVE Sbjct: 166 IGASNIVGRPMSMELLLAGCTTTVT-----HRFTKNL-----RHHVE------------- 202 Query: 243 SLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK---------NFSDDVKEKASLYVP 293 ++D++I V + P ++IKEGA+ I+ + +D ++AS P Sbjct: 203 --NADLLIVAVGKPGF-IPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITP 259 Query: 294 MTGKV---TIAMLLRNMLR 309 + G V T+A L+ N L+ Sbjct: 260 VPGGVGPMTVATLIENTLQ 278 >4A5O-A nrPDB Length = 286 Score = 87.8 bits (216), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 91/314 (28%), Positives = 131/314 (41%), Gaps = 66/314 (21%) Query: 13 VAETFNTEIINNVEEYKKTHNGQG---PLLVGFLANNDPAAKMYATWTQKTSESMGF--- 66 +A +I V E ++ QG P L L DPA+++Y +K E +GF Sbjct: 13 IAANLRQQIAQRVTERRQ----QGLRVPGLAVILVGTDPASQVYVAHKRKDCEEVGFLSQ 68 Query: 67 RYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHV 126 YDL +D L I + N D +++GI+V P+ + L + + +KDV+G H Sbjct: 69 AYDLPAETSQDDLLALIDRLNDDPAIDGILVQLPLPAHLDASLLLERIHPDKDVDGF-HP 127 Query: 127 YYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRS 186 Y N+ L R+ + PCTP I+ +L G LYG +V+ S Sbjct: 128 Y------NIGRL--AQRMPLLRPCTPKGIMTLLAS---------TGADLYGMDAVVVGAS 170 Query: 187 EIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDS 246 IVGRP+A L G TV +FTR DL ++ D Sbjct: 171 NIVGRPMALELLLGGCTVTVT-----HRFTR------------DLADHVS------RADL 207 Query: 247 DVVITGVPSENYKFPTEYIKEGAVCINFACTKN----FSDDVK-----EKASLYVPMTGK 297 VV G P E+IKEGA+ I+ + DV+ ++AS P+ G Sbjct: 208 VVVAAGKPG---LVKGEWIKEGAIVIDVGINRQADGRLVGDVEYEVAAQRASWITPVPGG 264 Query: 298 V---TIAMLLRNML 308 V T A LL N L Sbjct: 265 VGPMTRACLLENTL 278 >6DEB-A nrPDB Length = 285 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 78/287 (27%), Positives = 126/287 (43%), Gaps = 58/287 (20%) Query: 42 FLANNDPAAKMYATWTQKTSESMGFR---YDLRVIEDKDFLEEAIIQANGDDSVNGIMVY 98 L ++PA++ Y K E G + Y L ++ L I N DDSV+GI+V Sbjct: 39 ILVGDNPASQTYVKSKAKACEECGIKSLVYHLNENITQNELLALINTLNHDDSVHGILVQ 98 Query: 99 FPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKI 158 P+ + + + + KDV+G + + NV YL+ LPCTPL ++K+ Sbjct: 99 LPLPDHICKDLILESIISSKDVDGFHPI-------NVGYLNLGLE-SGFLPCTPLGVMKL 150 Query: 159 LEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRG 218 L+ +I L GK ++I S IVGRP+A +L N GATV + Sbjct: 151 LKAYEI---------DLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKT------- 194 Query: 219 ESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK 278 +DL Y+ +D++I N ++ +KEG + ++ + Sbjct: 195 ----------KDLSLYTR--------QADLIIVAAGCVNL-LRSDMVKEGVIVVDVGINR 235 Query: 279 NFS---------DDVKEKASLYVPMTGKV---TIAMLLRNMLRLVRN 313 S ++V +K+S P+ G V TIAMLL N ++ +N Sbjct: 236 LESGKIVGDVDFEEVSKKSSYITPVPGGVGPMTIAMLLENTVKSAKN 282 >5NHS-A nrPDB Length = 296 Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 90/321 (28%), Positives = 134/321 (41%), Gaps = 60/321 (18%) Query: 4 PGRTILASKVAETFNTEIINNVEEYKKTHNGQG-PLLVGFLANNDPAAKMYATWTQKTSE 62 P R + ++AE E+ V+ + GQ P L L DPA+ +Y ++ +E Sbjct: 11 PARILDGRRIAEDLLDELKTRVD--ARLAAGQPRPGLAVVLVGGDPASTVYVRNKRRAAE 68 Query: 63 SMG---FRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKD 119 +G F YDL + L I Q N D ++GI+V P+ G A L + KD Sbjct: 69 KVGIEAFDYDLPAGTGEAELLSLIDQLNADPKIHGILVQLPLPGIADASRLIHRIDPRKD 128 Query: 120 VEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKK 179 V+G + QN+ H +E L+ PCTP IV +L + G+ Sbjct: 129 VDGF---HPQNVGH---LALREFGLR---PCTPRGIVTLLAHTD---------QPVRGRN 170 Query: 180 CIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLL 239 ++ S VGRP+A L G TV KFT + L+ HV D D+L Sbjct: 171 ATIVGVSNHVGRPMALELLIAGCTVSCC-----HKFTPADVLQT---HVRD-----ADIL 217 Query: 240 KKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK----NFSDDV-----KEKASL 290 VV G P P +++K GAV I+ + DV ++AS Sbjct: 218 --------VVAVGRPG---LIPGDWVKPGAVVIDVGINRLDDGRLVGDVGFEAAAQRASW 266 Query: 291 YVPMTGKV---TIAMLLRNML 308 P+ G V T+A L++N + Sbjct: 267 ITPVPGGVGPMTVATLMQNTI 287 >3L07-A nrPDB Length = 285 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 82/306 (26%), Positives = 126/306 (41%), Gaps = 62/306 (20%) Query: 23 NNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMGFRYDLRVIED---KDFL 79 V+EYK H P LV + NDPA+K Y +K +G + + + + L Sbjct: 22 TQVQEYKH-HTAITPKLVAIIVGNDPASKTYVASKEKACAQVGIDSQVITLPEHTTESEL 80 Query: 80 EEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLD 139 E I Q N D SV+ I+V P+ + + + EKDV+G + NV L Sbjct: 81 LELIDQLNNDSSVHAILVQLPLPAHINKNNVIYSIKPEKDVDGFHPT-------NVGRLQ 133 Query: 140 KENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLAN 199 ++ K + CTP I+ L+ Y G + G +V+ S +VG+P++ LL N Sbjct: 134 LRDK-KCLESCTPKG---IMTMLREY------GIKTEGAYAVVVGASNVVGKPVSQLLLN 183 Query: 200 DGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYK 259 ATV + +FT LK + +D++I V N+ Sbjct: 184 AKATVTTC-----HRFTTD--------------------LKSHTTKADILIVAVGKPNF- 217 Query: 260 FPTEYIKEGAVCINFACTKNFSDD----------VKEKASLYVPMTGKV---TIAMLLRN 306 + +KEGAV I+ N D VK+K + P+ G V TI LL N Sbjct: 218 ITADMVKEGAVVIDVGI--NHVDGKIVGDVDFAAVKDKVAAITPVPGGVGPMTITELLYN 275 Query: 307 MLRLVR 312 + + Sbjct: 276 TFQCAQ 281 >4CJX-A nrPDB Length = 319 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 79/313 (25%), Positives = 139/313 (44%), Gaps = 43/313 (13%) Query: 13 VAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMGFR---YD 69 VA+ E+ V ++ + G+ P L + ++ Y +K + + GFR + Sbjct: 33 VAKAIQKELTEEVALLERRYKGRRPGLSTIICGKRKDSQTYVRLKRKAAAACGFRNFSVE 92 Query: 70 LRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQ 129 L ++ LE +I+ N +++ + I+V P+ + + EKD + L Sbjct: 93 LPANVTQEALEREVIRLNEEEACHSIVVQLPLPPHIDKVAALSKIKPEKDADCL------ 146 Query: 130 NLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIV 189 L NV L R +I+PCT A++++L G + GK+ +V+ R +I Sbjct: 147 -LPVNVGQLHIRERNPAIVPCTASAVMELLRC---------SGVEICGKRVVVLGRGDIA 196 Query: 190 GRPLAALLANDGATVYSV----DVNNIQKFTRGESLKLNKHHVEDL--GEYSEDLLKKCS 243 G P+A LLAN+ ATV V + +I R + ++ L GE+ +K + Sbjct: 197 GLPVATLLANEDATVTVVHSATPLCDIADIVRASDIVVSAAGQPGLVRGEW----IKLGA 252 Query: 244 LDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPM---TGKVTI 300 DV T V ++ K P Y G VC + A +++A+ P+ G VT+ Sbjct: 253 AVIDVGTTPV-ADPSKVPG-YRLVGDVCFDVA---------RKRAAYITPVPGGVGPVTV 301 Query: 301 AMLLRNMLRLVRN 313 +MLL+N L + + Sbjct: 302 SMLLKNTLTMFKR 314 >4A26-A nrPDB Length = 300 Score = 74.7 bits (182), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 81/327 (24%), Positives = 134/327 (40%), Gaps = 62/327 (18%) Query: 4 PGRTILASK-VAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSE 62 P I+ K +A +E+ + V ++ + G+ P L + +K Y K + Sbjct: 4 PSAQIIDGKAIAAAIRSELKDKVAALRELYGGRVPGLASIIVGQRMDSKKYVQLKHKAAA 63 Query: 63 SMGF-RYDLRVIED--KDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKD 119 +G +++ + ED ++ LE + + N D + +GI+V P+ + + + + KD Sbjct: 64 EVGMASFNVELPEDISQEVLEVNVEKLNNDPNCHGIIVQLPLPKHLNENRAIEKIHPHKD 123 Query: 120 VEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKK 179 + L L NV L + R PCT ++ +L+ I + GK+ Sbjct: 124 ADAL-------LPVNVGLLHYKGREPPFTPCTAKGVIVLLKRCGI---------EMAGKR 167 Query: 180 CIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLL 239 +V+ RS IVG P+AALL + ATV V G +ED++ Sbjct: 168 AVVLGRSNIVGAPVAALLMKENATVTIVHS----------------------GTSTEDMI 205 Query: 240 KKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK----------NFSDDV----- 284 +D+VI + Y E+IKEGA ++ T DV Sbjct: 206 DYLR-TADIVIAAMGQPGY-VKGEWIKEGAAVVDVGTTPVPDPSRKDGYRLVGDVCFEEA 263 Query: 285 KEKASLYVPMTGKV---TIAMLLRNML 308 +A+ P+ G V TIAMLL N L Sbjct: 264 AARAAWISPVPGGVGPMTIAMLLENTL 290 >5TC4-A nrPDB Length = 316 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 80/328 (24%), Positives = 141/328 (42%), Gaps = 57/328 (17%) Query: 8 ILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMGFR 67 I K+A+ E+ VEE+ + N + P L L +PA+ Y + + +G Sbjct: 6 ISGRKLAQQIKQEVRQEVEEWVASGNKR-PHLSVILVGENPASHSYVLNKTRAAAVVGIN 64 Query: 68 YDLRVIEDKDFLEE----AIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGL 123 + +++ EE I + N DD+V+G++V P+ + ++ + V +KDV+G Sbjct: 65 SET-IMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGF 123 Query: 124 NHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVI 183 + + + LD+ S+LP TP + +I++ I GK +V Sbjct: 124 HVINVGRM-----CLDQ----YSMLPATPWGVWEIIKRTGIPT---------LGKNVVVA 165 Query: 184 NRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCS 243 RS+ VG P+A LL DGA + G++ H ++ LKK + Sbjct: 166 GRSKNVGMPIAMLLHTDGA----------HERPGGDATVTISHRY-----TPKEQLKKHT 210 Query: 244 LDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFS--------------DDVKEKAS 289 + +D+VI+ N + IKEGA I+ + + V++KA Sbjct: 211 ILADIVISAAGIPNL-ITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAG 269 Query: 290 LYVPMTGKV---TIAMLLRNMLRLVRNV 314 P+ G V T+AML++N + + V Sbjct: 270 YITPVPGGVGPMTVAMLMKNTIIAAKKV 297 >5ZF1-A nrPDB Length = 301 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 76/332 (22%), Positives = 139/332 (41%), Gaps = 61/332 (18%) Query: 5 GRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESM 64 R + +A E+ + ++ N + P + + +DPA+ Y + ++ + Sbjct: 2 ARILDGKALAMEIKKELKQKIAQWVSLGN-RAPTIRCIIVGDDPASHTYVRNKVEAAKFV 60 Query: 65 GFRYDLRVIEDKDFLEEAIIQA----NGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDV 120 G L + D D EE ++ N D+SV+GI+V PV ++ + + EKD+ Sbjct: 61 GIDA-LTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDI 119 Query: 121 EGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKC 180 +G + + L + L +I+P T LA+V++L+ I +G+ Sbjct: 120 DGFHIINIGRLCVD---------LPTIVPATALAVVEMLKRFNIDT---------FGRNA 161 Query: 181 IVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYS-EDLL 239 +VI RS+ VG P+A +L +D R ES V Y+ +D L Sbjct: 162 VVIGRSKNVGMPIAMMLHSD---------------KRHESGLGMDATVTICHRYTPKDKL 206 Query: 240 KKCSLDSDVVI--TGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEK---------- 287 + ++D++I TG+P + +K GA I+ T ++ K + Sbjct: 207 EAYCRNADIIITATGLPK---LIKADMVKPGATIIDVGITTRTDENGKSRLVGDVDYEEV 263 Query: 288 ---ASLYVPMTGKV---TIAMLLRNMLRLVRN 313 A P+ G V T+AML+ N + ++ Sbjct: 264 SKIAGAITPVPGGVGPMTVAMLMHNTFQAAQS 295 >6APE-A nrPDB Length = 298 Score = 67.8 bits (164), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 55/220 (25%), Positives = 98/220 (44%), Gaps = 26/220 (11%) Query: 37 PLLVGFLANNDPAAKMYATWTQKTSESMGFRYDLRVIED---KDFLEEAIIQANGDDSVN 93 P L L DPA+ Y K E +G +DL+ +++ + L I N D +++ Sbjct: 45 PKLAVILVGKDPASITYVNMKIKACERVGMDFDLKTLQENVTEAELLSLIKDYNTDQNIS 104 Query: 94 GIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPL 153 G++V P+ + + + + + KDV+G +H + + +S LP TP+ Sbjct: 105 GVLVQLPLPRHIDSKMVLEAIDPSKDVDG---------FHPLNIGKLCTQKESFLPATPM 155 Query: 154 AIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQ 213 ++++L+ I + GK +I S I+G+PL+ L+ N GA SV V +I Sbjct: 156 GVMRLLKHYHI---------EIKGKDVAIIGASNIIGKPLSMLMLNAGA---SVSVCHI- 202 Query: 214 KFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGV 253 T+ S + +G DL+K L V+ + Sbjct: 203 -LTKDISFYTQNADIVCVGVGKPDLIKASMLKKGAVVVDI 241 >1DIA-A nrPDB Length = 306 Score = 60.8 bits (146), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 80/331 (24%), Positives = 134/331 (40%), Gaps = 71/331 (21%) Query: 4 PGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSES 63 P + +++ + N V + K+ G P L N + +Y K +E Sbjct: 3 PAEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEE 62 Query: 64 MGFRYD----LRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFG--NAQDQYLQQVVCKE 117 +G + R + + ++ I N D +V+G +V P+ + + + + E Sbjct: 63 IGIKATHIKLPRTTTESEVMK-YITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPE 121 Query: 118 KDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYG 177 KDV+GL + N L + + +PCTP LE +K G + G Sbjct: 122 KDVDGLTSI-------NAGRLARGDLNDCFIPCTPKGC---LELIK------ETGVPIAG 165 Query: 178 KKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSED 237 + +V+ RS+IVG P+ LL + ATV + H E++ + D Sbjct: 166 RHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSK-------------TAHLDEEVNKG--D 210 Query: 238 LLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFS---------------- 281 +L VV TG P E K E+IK GA+ I+ C N+ Sbjct: 211 IL--------VVATGQP-EMVK--GEWIKPGAIVID--CGINYVPDDKKPNGRKVVGDVA 257 Query: 282 -DDVKEKASLYVPMTGKV---TIAMLLRNML 308 D+ KE+AS P+ G V T+AML+++ + Sbjct: 258 YDEAKERASFITPVPGGVGPMTVAMLMQSTV 288 >2C2Y-A nrPDB Length = 281 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 68/290 (23%), Positives = 103/290 (35%), Gaps = 55/290 (18%) Query: 34 GQGPLLVGFLANNDPAAKMYATWTQKTSESMGF---RYDLRVIEDKDFLEEAIIQANGDD 90 G+ P L L +DP ++ Y +G R DL L E I + N + Sbjct: 30 GRTPGLGTILVGDDPGSQAYVRGKHADCAKVGITSIRRDLPADISTATLNETIDELNANP 89 Query: 91 SVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPC 150 G +V P+ + + + V KD +GL+ L + LPC Sbjct: 90 DCTGYIVQLPLPKHLDENAALERVDPAKDADGLHPTNLGRLVLGT---------PAPLPC 140 Query: 151 TPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVN 210 TP IV +L I + G +VI R VGRPL LL Sbjct: 141 TPRGIVHLLRRYDIS---------IAGAHVVVIGRGVTVGRPLGLLLTR----------- 180 Query: 211 NIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAV 270 R E+ + H + D L + +D+V+ V + + ++ GA Sbjct: 181 ------RSENATVTLCHTG-----TRD-LPALTRQADIVVAAV-GVAHLLTADMVRPGAA 227 Query: 271 CINFACTK-------NFSDDVKEKASLYVPMTGKV---TIAMLLRNMLRL 310 I+ ++ + DV E A P G V T A LL N++ L Sbjct: 228 VIDVGVSRTDDGLVGDVHPDVWELAGHVSPNPGGVGPLTRAFLLTNVVEL 277 >4B4V-A nrPDB Length = 303 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 69/294 (23%), Positives = 115/294 (39%), Gaps = 58/294 (19%) Query: 27 EYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMG---FRYDLRVIEDKDFLEEAI 83 E K G+ P+L L +D A+ Y +G + +L + L I Sbjct: 44 EALKAKTGRTPILATILVGDDGASATYVRMKGNACRRVGMDSLKIELPQETTTEQLLAEI 103 Query: 84 IQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENR 143 + N + V+GI++ PV ++ + KDV+G+ + + R E Sbjct: 104 EKLNANPDVHGILLQHPVPAQIDERACFDAISLAKDVDGVTCLGFG------RMAMGEAA 157 Query: 144 LKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGAT 203 S TP I+ IL+ NN+ + GK +V+ RS I+G+P+A +L AT Sbjct: 158 YGS---ATPAGIMTILK----ENNI-----EIAGKHAVVVGRSAILGKPMAMMLLQANAT 205 Query: 204 VYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTE 263 V +R ++L +L+K+ +I G + + Sbjct: 206 VTIC-------HSRTQNLP--------------ELVKQAD-----IIVGAVGKAELIQKD 239 Query: 264 YIKEGAVCINFACTKNFSDDV--------KEKASLYVPMTGKV---TIAMLLRN 306 +IK+GAV ++ V +E AS Y P+ G V TI L+R Sbjct: 240 WIKQGAVVVDAGFHPRDGGGVGDIQLQGIEEIASAYTPVPGGVGPMTITTLIRQ 293 >3NGX-A nrPDB Length = 276 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 48/176 (27%), Positives = 80/176 (45%), Gaps = 24/176 (13%) Query: 32 HNGQGPLLVGFLANNDPAAKMYATWTQKTSESMGFRYDLRVIED---KDFLEEAIIQANG 88 +G P L ++ AA +YA + + +G DL +D KD L+ I Sbjct: 23 RSGLEPSLKLIQIGDNEAASIYARAKIRRGKKIGIAVDLEKYDDISMKDLLKR-IDDLAK 81 Query: 89 DDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSIL 148 D +NGIM+ P+ + + + KDV+ L+ Y Q L L++E ++ Sbjct: 82 DPQINGIMIENPLPKGFDYYEIVRNIPYYKDVDALSP-YNQGLIA----LNRE----FLV 132 Query: 149 PCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATV 204 P TP A++ I+++ + N ++NRS +VGRPL+ +L N TV Sbjct: 133 PATPRAVIDIMDYYGYHEN-----------TVTIVNRSPVVGRPLSMMLLNRNYTV 177 >3RWB-A nrPDB Length = 247 Score = 37.4 bits (85), Expect = 0.009, Method: Compositional matrix adjust. Identities = 17/37 (45%), Positives = 24/37 (64%) Query: 174 RLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVN 210 RL GK +V ++ +G+ +AA LA DGATV D+N Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDIN 39 >5Y3K-A nrPDB Length = 802 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 26/43 (60%) Query: 127 YYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLL 169 ++Q L +R +NRL ++LPCT + K L+ L++ NN L Sbjct: 602 FFQGLRSLIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYL 644 >2X6Q-A nrPDB Length = 416 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 6/56 (10%) Query: 21 IINNVEEYKKTHN---GQGPLLVGFLANNDPAAKMYATWTQKTSESMGFRYDLRVI 73 I + +E Y+K G LLVG +A++DP +Y +KT +G YD++V+ Sbjct: 246 IFDVIEIYRKVKEKIPGVQLLLVGVMAHDDPEGWIY---FEKTLRKIGEDYDVKVL 298 >3U4C-A nrPDB Length = 281 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 17/91 (18%) Query: 168 LLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHH 227 L+P G+ + + V+ S+ +G+ +A LA+ Q F SL +N + Sbjct: 14 LVPRGSHMSKRTAFVMGASQGIGKAIALKLAD-------------QHF----SLVINSRN 56 Query: 228 VEDLGEYSEDLLKKCSLDSDVVITGVPSENY 258 ++++ ED+L K S +V+ G S+ + Sbjct: 57 LDNIESVKEDILAKHPEASVIVLAGDMSDQH 87 >3OEC-A nrPDB Length = 317 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 5/65 (7%) Query: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQK---FTRG--ESLKLNKHH 227 NRL GK + + GR A LA DGA + ++D+ Q + +G E LK Sbjct: 42 NRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRL 101 Query: 228 VEDLG 232 VE+ G Sbjct: 102 VEEQG 106 >5M6C-E nrPDB Length = 193 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 2/47 (4%) Query: 129 QNLYHNVRY--LDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGN 173 Q+L N + L+ + K L P I+ + EF KIY N P G+ Sbjct: 14 QDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGD 60 >5MRJ-A nrPDB Length = 396 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 20/138 (14%) Query: 102 FGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIV----- 156 +GNA D + V K + G V++ L V+ ++ N L ++ A+V Sbjct: 153 WGNA-DAVVDFAVANGKMIRGHTLVWHSQLPDWVKQINDRNTLTQVIEDHVTAMVTRYKG 211 Query: 157 KILEFLKIYNNLLPE-GN-------RLYGKKCIVIN-RSEIVGRPLAALLANDGATVYSV 207 KI+ + + N + E GN R+ G+ + I R+ P A L ND Y++ Sbjct: 212 KIVHW-DVVNEIFSEDGNLRDSVFSRVLGEDFVGIAFRAARAADPNAKLYIND----YNL 266 Query: 208 DVNNIQKFTRGESLKLNK 225 D N K TRG K+N+ Sbjct: 267 DNANYAKVTRGMVEKVNR 284 >4FXY-P nrPDB Length = 693 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 3/39 (7%) Query: 168 LLPEGNRLYGKKCIVINRSE-IVGRPLAALLANDGATVY 205 LLP+G+R+ +V+N S+ + GRP +LL +D Y Sbjct: 448 LLPDGSRMMSVAALVVNFSQPVAGRP--SLLRHDEVRTY 484 >5LV0-A nrPDB Length = 686 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 3/39 (7%) Query: 168 LLPEGNRLYGKKCIVINRSE-IVGRPLAALLANDGATVY 205 LLP+G+R+ +V+N S+ + GRP +LL +D Y Sbjct: 441 LLPDGSRMMAVAALVVNFSQPVAGRP--SLLRHDEVRTY 477 >2DPD-A nrPDB Length = 122 Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 20/34 (58%) Query: 155 IVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEI 188 +VK FLK+Y + E RLYG K + + RSE Sbjct: 12 LVKQRAFLKLYMITMTEQERLYGLKLLEVLRSEF 45 >6IB8-A nrPDB Length = 271 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 8/64 (12%) Query: 202 ATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFP 261 A VY N + TRG+ +LN + + G + DL D ++ TG P + ++ Sbjct: 118 AVVYDPMRNELFTATRGQGAQLNGYRLR--GSTARDL------DGTILATGFPFKAKQYA 169 Query: 262 TEYI 265 T YI Sbjct: 170 TTYI 173 >3WOH-A nrPDB Length = 251 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 175 LYGKKCIVINRSEIVGRPLAALLANDGATVYSVDV--NNIQKFTRGESLKLN 224 L GK +V S +GR +A LA DGA V V V ++ K T+GE +L Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLG 60 >1LU9-A nrPDB Length = 287 Score = 28.5 bits (62), Expect = 4.1, Method: Compositional matrix adjust. Identities = 15/33 (45%), Positives = 20/33 (60%) Query: 172 GNRLYGKKCIVINRSEIVGRPLAALLANDGATV 204 G + GKK +V+ + VG AALLA +GA V Sbjct: 114 GGSVKGKKAVVLAGTGPVGMRSAALLAGEGAEV 146 >2BDQ-A nrPDB Length = 224 Score = 28.1 bits (61), Expect = 6.0, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 20/32 (62%) Query: 236 EDLLKKCSLDSDVVITGVPSENYKFPTEYIKE 267 ED+L+ L+SD ++ G+ + N TE I++ Sbjct: 80 EDILRAVELESDALVLGILTSNNHIDTEAIEQ 111 >4E6P-A nrPDB Length = 259 Score = 27.7 bits (60), Expect = 7.1, Method: Compositional matrix adjust. Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 174 RLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVN 210 RL GK ++ + +GR A +GATV D++ Sbjct: 5 RLEGKSALITGSARGIGRAFAEAYVREGATVAIADID 41 >1C7O-A nrPDB Length = 399 Score = 27.7 bits (60), Expect = 7.8, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 88 GDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSI 147 GD + VY+P F ++Q + + C+ + +G YY + + L K+ K++ Sbjct: 113 GDGVIIITPVYYPFFMAIKNQERKIIECELLEKDG----YYTIDFQKLEKLSKDKNNKAL 168 Query: 148 LPCTP 152 L C+P Sbjct: 169 LFCSP 173 >1HXH-A nrPDB Length = 253 Score = 27.3 bits (59), Expect = 8.1, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 20/38 (52%) Query: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVN 210 NRL GK +V + VG + LL +GA V D+N Sbjct: 2 NRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDIN 39 >1Y23-A nrPDB Length = 145 Score = 27.3 bits (59), Expect = 9.0, Method: Compositional matrix adjust. Identities = 10/31 (32%), Positives = 23/31 (74%) Query: 211 NIQKFTRGESLKLNKHHVEDLGEYSEDLLKK 241 +I + T+G +L + K H+E++ E++++L K+ Sbjct: 33 DISQVTKGHTLVIPKTHIENVYEFTDELAKQ 63 >3F3S-A nrPDB Length = 313 Score = 27.3 bits (59), Expect = 9.6, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 3/75 (4%) Query: 180 CIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLL 239 C+VI S ++GR A L A+ G V D+ Q E+++ +E G L Sbjct: 5 CVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLS 64 Query: 240 KKCSLDSDVVITGVP 254 + L +I+G P Sbjct: 65 VEEQLS---LISGCP 76 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1EDZ-A nrPDB 409 e-115 5O2A-B nrPDB 293 6e-80 4A5O-A nrPDB 292 1e-79 4A26-A nrPDB 285 2e-77 5NHS-A nrPDB 283 7e-77 5ZF1-A nrPDB 275 2e-74 6DEB-A nrPDB 275 2e-74 3L07-A nrPDB 272 1e-73 5TC4-A nrPDB 268 3e-72 1DIA-A nrPDB 268 3e-72 4CJX-A nrPDB 262 1e-70 6APE-A nrPDB 249 1e-66 4B4V-A nrPDB 249 2e-66 2C2Y-A nrPDB 247 5e-66 3NGX-A nrPDB 197 5e-51 Sequences not found previously or not previously below threshold: 4PPM-A nrPDB 41 5e-04 2EEZ-A nrPDB 38 0.007 1MLD-A nrPDB 36 0.017 1SMK-A nrPDB 36 0.025 4WLE-A nrPDB 36 0.028 1O5I-A nrPDB 35 0.037 1DOH-A nrPDB 35 0.040 1LU9-A nrPDB 34 0.061 3W8F-A nrPDB 34 0.12 4JA0-A nrPDB 34 0.12 3RWB-A nrPDB 34 0.12 4FS8-A nrPDB 34 0.12 3WOH-A nrPDB 33 0.17 3CKY-A nrPDB 32 0.35 4KDC-A nrPDB 32 0.45 1K24-A nrPDB 31 0.49 4NBT-A nrPDB 31 0.61 6CI9-A nrPDB 31 0.70 3DWF-A nrPDB 31 0.83 3RAC-A nrPDB 31 1.0 1HXH-A nrPDB 31 1.0 3QQW-A nrPDB 31 1.0 5PGZ-A nrPDB 30 1.3 3RSH-A nrPDB 30 1.5 4BVA-A nrPDB 30 1.7 1BRW-A nrPDB 30 1.7 2I99-A nrPDB 30 1.7 3F9I-A nrPDB 30 1.7 4DIO-A nrPDB 29 2.4 4Z53-A nrPDB 29 2.5 4TRR-A nrPDB 29 2.6 3OML-A nrPDB 29 2.6 5HUN-A nrPDB 29 2.6 2UVD-A nrPDB 29 2.9 4MOW-A nrPDB 29 3.0 5J3U-A nrPDB 29 3.2 4KPF-A nrPDB 29 3.3 2PKW-A nrPDB 29 3.7 4CQL-A nrPDB 29 3.8 1HYE-A nrPDB 29 4.0 5CDY-A nrPDB 28 4.1 4DMM-A nrPDB 28 4.2 5K1S-A nrPDB 28 4.6 4E6P-A nrPDB 28 4.6 3M84-A nrPDB 28 4.8 3WTC-A nrPDB 28 5.3 3D3W-A nrPDB 28 5.6 5XAN-A nrPDB 28 6.0 2X9N-A nrPDB 28 7.3 3FTP-A nrPDB 27 9.2 >1EDZ-A nrPDB Length = 320 Score = 409 bits (1051), Expect = e-115, Method: Composition-based stats. Identities = 320/320 (100%), Positives = 320/320 (100%) Query: 1 MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKT 60 MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKT Sbjct: 1 MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKT 60 Query: 61 SESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDV 120 SESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDV Sbjct: 61 SESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDV 120 Query: 121 EGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKC 180 EGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKC Sbjct: 121 EGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKC 180 Query: 181 IVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLK 240 IVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLK Sbjct: 181 IVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLK 240 Query: 241 KCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTI 300 KCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTI Sbjct: 241 KCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTI 300 Query: 301 AMLLRNMLRLVRNVELSKEK 320 AMLLRNMLRLVRNVELSKEK Sbjct: 301 AMLLRNMLRLVRNVELSKEK 320 >5O2A-B nrPDB Length = 289 Score = 293 bits (750), Expect = 6e-80, Method: Composition-based stats. Identities = 77/321 (23%), Positives = 133/321 (41%), Gaps = 60/321 (18%) Query: 5 GRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESM 64 + I +A+ +E+ V+ + + P L L ++PA+++Y +K E + Sbjct: 4 AKIIDGKTIAQQVRSEVAQKVQA-RIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEV 62 Query: 65 GF---RYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVE 121 GF YDL + L E I N D++++GI+V+ P+ + + + + +KDV+ Sbjct: 63 GFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVHLPLPAGIDNVKVLERIHPDKDVD 122 Query: 122 GLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCI 181 G + L R + PCTP IV +LE I +G + Sbjct: 123 GFHPYNVGRLC---------QRAPRLRPCTPRGIVTLLERYNIDT---------FGLNAV 164 Query: 182 VINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKK 241 VI S IVGRP++ L G T +FT+ L+ Sbjct: 165 VIGASNIVGRPMSMELLLAGCTTTVT-----HRFTKN--------------------LRH 199 Query: 242 CSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK---------NFSDDVKEKASLYV 292 ++D++I V + P ++IKEGA+ I+ + +D ++AS Sbjct: 200 HVENADLLIVAVGKPGF-IPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYIT 258 Query: 293 PMTGKV---TIAMLLRNMLRL 310 P+ G V T+A L+ N L+ Sbjct: 259 PVPGGVGPMTVATLIENTLQA 279 >4A5O-A nrPDB Length = 286 Score = 292 bits (747), Expect = 1e-79, Method: Composition-based stats. Identities = 83/325 (25%), Positives = 128/325 (39%), Gaps = 60/325 (18%) Query: 5 GRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESM 64 + I +A +I V E ++ + P L L DPA+++Y +K E + Sbjct: 5 AQLIDGKAIAANLRQQIAQRVTE-RRQQGLRVPGLAVILVGTDPASQVYVAHKRKDCEEV 63 Query: 65 GF---RYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVE 121 GF YDL +D L I + N D +++GI+V P+ + L + + +KDV+ Sbjct: 64 GFLSQAYDLPAETSQDDLLALIDRLNDDPAIDGILVQLPLPAHLDASLLLERIHPDKDVD 123 Query: 122 GLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCI 181 G + L R+ + PCTP I+ +L G LYG + Sbjct: 124 GFHPYNIGRL---------AQRMPLLRPCTPKGIMTLLA---------STGADLYGMDAV 165 Query: 182 VINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKK 241 V+ S IVGRP+A L G TV +FTR L Sbjct: 166 VVGASNIVGRPMALELLLGGCTVTVT-----HRFTRD--------------------LAD 200 Query: 242 CSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK----NFSDDVK-----EKASLYV 292 +D+V+ E+IKEGA+ I+ + DV+ ++AS Sbjct: 201 HVSRADLVVVAAGKPG-LVKGEWIKEGAIVIDVGINRQADGRLVGDVEYEVAAQRASWIT 259 Query: 293 PMTGKV---TIAMLLRNMLRLVRNV 314 P+ G V T A LL N L ++ Sbjct: 260 PVPGGVGPMTRACLLENTLHAAEHL 284 >4A26-A nrPDB Length = 300 Score = 285 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 79/329 (24%), Positives = 130/329 (39%), Gaps = 61/329 (18%) Query: 5 GRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESM 64 + I +A +E+ + V ++ + G+ P L + +K Y K + + Sbjct: 6 AQIIDGKAIAAAIRSELKDKVAALRELYGGRVPGLASIIVGQRMDSKKYVQLKHKAAAEV 65 Query: 65 G---FRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVE 121 G F +L ++ LE + + N D + +GI+V P+ + + + + KD + Sbjct: 66 GMASFNVELPEDISQEVLEVNVEKLNNDPNCHGIIVQLPLPKHLNENRAIEKIHPHKDAD 125 Query: 122 GLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCI 181 L L NV L + R PCT ++ +L+ I + GK+ + Sbjct: 126 AL-------LPVNVGLLHYKGREPPFTPCTAKGVIVLLKRCGI---------EMAGKRAV 169 Query: 182 VINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKK 241 V+ RS IVG P+AALL + ATV V G +ED++ Sbjct: 170 VLGRSNIVGAPVAALLMKENATVTIVHS----------------------GTSTEDMIDY 207 Query: 242 CSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK----------NFSDDV-----KE 286 +D+VI + Y E+IKEGA ++ T DV Sbjct: 208 L-RTADIVIAAMGQPGY-VKGEWIKEGAAVVDVGTTPVPDPSRKDGYRLVGDVCFEEAAA 265 Query: 287 KASLYVPMTGKV---TIAMLLRNMLRLVR 312 +A+ P+ G V TIAMLL N L + Sbjct: 266 RAAWISPVPGGVGPMTIAMLLENTLEAFK 294 >5NHS-A nrPDB Length = 296 Score = 283 bits (723), Expect = 7e-77, Method: Composition-based stats. Identities = 79/323 (24%), Positives = 124/323 (38%), Gaps = 58/323 (17%) Query: 4 PGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSES 63 P R + ++AE E+ V+ + P L L DPA+ +Y ++ +E Sbjct: 11 PARILDGRRIAEDLLDELKTRVDARLAAGQPR-PGLAVVLVGGDPASTVYVRNKRRAAEK 69 Query: 64 MG---FRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDV 120 +G F YDL + L I Q N D ++GI+V P+ G A L + KDV Sbjct: 70 VGIEAFDYDLPAGTGEAELLSLIDQLNADPKIHGILVQLPLPGIADASRLIHRIDPRKDV 129 Query: 121 EGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKC 180 +G + R + PCTP IV +L + G+ Sbjct: 130 DGFHPQNVG---------HLALREFGLRPCTPRGIVTLLAHTD---------QPVRGRNA 171 Query: 181 IVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLK 240 ++ S VGRP+A L G TV KFT D+L+ Sbjct: 172 TIVGVSNHVGRPMALELLIAGCTVSCC-----HKFTPA------------------DVLQ 208 Query: 241 KCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK----NFSDDV-----KEKASLY 291 D+D+++ V P +++K GAV I+ + DV ++AS Sbjct: 209 THVRDADILVVAVGRPG-LIPGDWVKPGAVVIDVGINRLDDGRLVGDVGFEAAAQRASWI 267 Query: 292 VPMTGKV---TIAMLLRNMLRLV 311 P+ G V T+A L++N + Sbjct: 268 TPVPGGVGPMTVATLMQNTIEAA 290 >5ZF1-A nrPDB Length = 301 Score = 275 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 71/329 (21%), Positives = 132/329 (40%), Gaps = 55/329 (16%) Query: 5 GRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESM 64 R + +A E+ + ++ N + P + + +DPA+ Y + ++ + Sbjct: 2 ARILDGKALAMEIKKELKQKIAQWVSLGN-RAPTIRCIIVGDDPASHTYVRNKVEAAKFV 60 Query: 65 GFRY---DLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVE 121 G + ++ L I N D+SV+GI+V PV ++ + + EKD++ Sbjct: 61 GIDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDID 120 Query: 122 GLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCI 181 G + + L + L +I+P T LA+V++L+ I +G+ + Sbjct: 121 GFHIINIGRLCVD---------LPTIVPATALAVVEMLKRFNIDT---------FGRNAV 162 Query: 182 VINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSE-DLLK 240 VI RS+ VG P+A +L +D R ES V Y+ D L+ Sbjct: 163 VIGRSKNVGMPIAMMLHSD---------------KRHESGLGMDATVTICHRYTPKDKLE 207 Query: 241 KCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEK------------- 287 ++D++IT + +K GA I+ T ++ K + Sbjct: 208 AYCRNADIIITATGLPK-LIKADMVKPGATIIDVGITTRTDENGKSRLVGDVDYEEVSKI 266 Query: 288 ASLYVPMTGKV---TIAMLLRNMLRLVRN 313 A P+ G V T+AML+ N + ++ Sbjct: 267 AGAITPVPGGVGPMTVAMLMHNTFQAAQS 295 >6DEB-A nrPDB Length = 285 Score = 275 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 80/327 (24%), Positives = 132/327 (40%), Gaps = 60/327 (18%) Query: 2 SKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTS 61 S + ++ E+ + K G L L ++PA++ Y K Sbjct: 1 SNAMTLLDGKALSAKIKEELKEKNQFLKS--KGIESCLAVILVGDNPASQTYVKSKAKAC 58 Query: 62 ESMGFR---YDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEK 118 E G + Y L ++ L I N DDSV+GI+V P+ + + + + K Sbjct: 59 EECGIKSLVYHLNENITQNELLALINTLNHDDSVHGILVQLPLPDHICKDLILESIISSK 118 Query: 119 DVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGK 178 DV+G + + NV YL+ LPCTPL ++K+L+ +I L GK Sbjct: 119 DVDGFHPI-------NVGYLNLG-LESGFLPCTPLGVMKLLKAYEI---------DLEGK 161 Query: 179 KCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDL 238 ++I S IVGRP+A +L N GATV + Sbjct: 162 DAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKD------------------------- 196 Query: 239 LKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK---------NFSDDVKEKAS 289 L + +D++I N ++ +KEG + ++ + ++V +K+S Sbjct: 197 LSLYTRQADLIIVAAGCVN-LLRSDMVKEGVIVVDVGINRLESGKIVGDVDFEEVSKKSS 255 Query: 290 LYVPMTGKV---TIAMLLRNMLRLVRN 313 P+ G V TIAMLL N ++ +N Sbjct: 256 YITPVPGGVGPMTIAMLLENTVKSAKN 282 >3L07-A nrPDB Length = 285 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 81/322 (25%), Positives = 126/322 (39%), Gaps = 58/322 (18%) Query: 7 TILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMGF 66 I +++ + V+EYK H P LV + NDPA+K Y +K +G Sbjct: 6 LIDGKSLSKDLKERLATQVQEYKH-HTAITPKLVAIIVGNDPASKTYVASKEKACAQVGI 64 Query: 67 RYD---LRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGL 123 L + L E I Q N D SV+ I+V P+ + + + EKDV+G Sbjct: 65 DSQVITLPEHTTESELLELIDQLNNDSSVHAILVQLPLPAHINKNNVIYSIKPEKDVDGF 124 Query: 124 NHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVI 183 + NV L ++ K + CTP I+ +L I G +V+ Sbjct: 125 HPT-------NVGRLQLRDK-KCLESCTPKGIMTMLREYGIKT---------EGAYAVVV 167 Query: 184 NRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCS 243 S +VG+P++ LL N ATV + +FT LK + Sbjct: 168 GASNVVGKPVSQLLLNAKATVTTC-----HRFTTD--------------------LKSHT 202 Query: 244 LDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSD--------DVKEKASLYVPMT 295 +D++I V N+ + +KEGAV I+ VK+K + P+ Sbjct: 203 TKADILIVAVGKPNF-ITADMVKEGAVVIDVGINHVDGKIVGDVDFAAVKDKVAAITPVP 261 Query: 296 GKV---TIAMLLRNMLRLVRNV 314 G V TI LL N + + + Sbjct: 262 GGVGPMTITELLYNTFQCAQEL 283 >5TC4-A nrPDB Length = 316 Score = 268 bits (684), Expect = 3e-72, Method: Composition-based stats. Identities = 78/336 (23%), Positives = 140/336 (41%), Gaps = 55/336 (16%) Query: 5 GRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESM 64 I K+A+ E+ VEE+ + N + P L L +PA+ Y + + + Sbjct: 3 AVVISGRKLAQQIKQEVRQEVEEWVASGNKR-PHLSVILVGENPASHSYVLNKTRAAAVV 61 Query: 65 GFRYDL---RVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVE 121 G + ++ L I + N DD+V+G++V P+ + ++ + V +KDV+ Sbjct: 62 GINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVD 121 Query: 122 GLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCI 181 G + + + + S+LP TP + +I++ I GK + Sbjct: 122 GFHVINVGRMCLD---------QYSMLPATPWGVWEIIKRTGIPT---------LGKNVV 163 Query: 182 VINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKK 241 V RS+ VG P+A LL DGA + G++ H ++ LKK Sbjct: 164 VAGRSKNVGMPIAMLLHTDGA----------HERPGGDATVTISHRYT-----PKEQLKK 208 Query: 242 CSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFS--------------DDVKEK 287 ++ +D+VI+ N + IKEGA I+ + + V++K Sbjct: 209 HTILADIVISAAGIPN-LITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQK 267 Query: 288 ASLYVPMTGKV---TIAMLLRNMLRLVRNVELSKEK 320 A P+ G V T+AML++N + + V +E+ Sbjct: 268 AGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEER 303 >1DIA-A nrPDB Length = 306 Score = 268 bits (684), Expect = 3e-72, Method: Composition-based stats. Identities = 67/333 (20%), Positives = 124/333 (37%), Gaps = 65/333 (19%) Query: 4 PGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSES 63 P + +++ + N V + K+ G P L N + +Y K +E Sbjct: 3 PAEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEE 62 Query: 64 MGFRYD---LRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFG--NAQDQYLQQVVCKEK 118 +G + L + + + I N D +V+G +V P+ + + + + EK Sbjct: 63 IGIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEK 122 Query: 119 DVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGK 178 DV+GL + N L + + +PCTP +++++ G + G+ Sbjct: 123 DVDGLTSI-------NAGRLARGDLNDCFIPCTPKGCLELIK---------ETGVPIAGR 166 Query: 179 KCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDL 238 +V+ RS+IVG P+ LL + ATV + Sbjct: 167 HAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTAH------------------------- 201 Query: 239 LKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACT----------KNFSDDV---- 284 L + D+++ E+IK GA+ I+ + DV Sbjct: 202 LDEEVNKGDILVVATGQP-EMVKGEWIKPGAIVIDCGINYVPDDKKPNGRKVVGDVAYDE 260 Query: 285 -KEKASLYVPMTGKV---TIAMLLRNMLRLVRN 313 KE+AS P+ G V T+AML+++ + + Sbjct: 261 AKERASFITPVPGGVGPMTVAMLMQSTVESAKR 293 >4CJX-A nrPDB Length = 319 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 78/319 (24%), Positives = 137/319 (42%), Gaps = 39/319 (12%) Query: 5 GRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESM 64 I VA+ E+ V ++ + G+ P L + ++ Y +K + + Sbjct: 25 AVVIDGRAVAKAIQKELTEEVALLERRYKGRRPGLSTIICGKRKDSQTYVRLKRKAAAAC 84 Query: 65 GFR---YDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVE 121 GFR +L ++ LE +I+ N +++ + I+V P+ + + EKD + Sbjct: 85 GFRNFSVELPANVTQEALEREVIRLNEEEACHSIVVQLPLPPHIDKVAALSKIKPEKDAD 144 Query: 122 GLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCI 181 L L NV L R +I+PCT A++++L G + GK+ + Sbjct: 145 CL-------LPVNVGQLHIRERNPAIVPCTASAVMELLRC---------SGVEICGKRVV 188 Query: 182 VINRSEIVGRPLAALLANDGATVYSVDV----NNIQKFTRGESLKLNKHHVEDLGEYSED 237 V+ R +I G P+A LLAN+ ATV V +I R + ++ L + Sbjct: 189 VLGRGDIAGLPVATLLANEDATVTVVHSATPLCDIADIVRASDIVVSAAGQPGLVRG--E 246 Query: 238 LLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGK 297 +K + DV T V ++ K P Y G VC + A +++A+ P+ G Sbjct: 247 WIKLGAAVIDVGTTPV-ADPSKVPG-YRLVGDVCFDVA---------RKRAAYITPVPGG 295 Query: 298 ---VTIAMLLRNMLRLVRN 313 VT++MLL+N L + + Sbjct: 296 VGPVTVSMLLKNTLTMFKR 314 >6APE-A nrPDB Length = 298 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 65/322 (20%), Positives = 122/322 (37%), Gaps = 60/322 (18%) Query: 7 TILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMGF 66 + +A + ++ N ++ + + P L L DPA+ Y K E +G Sbjct: 16 LLDGQALAYSIEKDLKNKIQIITVQVHKR-PKLAVILVGKDPASITYVNMKIKACERVGM 74 Query: 67 RYDLRV---IEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGL 123 +DL+ + L I N D +++G++V P+ + + + + + KDV+G Sbjct: 75 DFDLKTLQENVTEAELLSLIKDYNTDQNISGVLVQLPLPRHIDSKMVLEAIDPSKDVDGF 134 Query: 124 NHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVI 183 + + L + +S LP TP+ ++++L+ I + GK +I Sbjct: 135 HPLNIGKLC---------TQKESFLPATPMGVMRLLKHYHI---------EIKGKDVAII 176 Query: 184 NRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCS 243 S I+G+PL+ L+ N GA+V + T+ S Sbjct: 177 GASNIIGKPLSMLMLNAGASVSVCHI-----LTKDISFYTQ------------------- 212 Query: 244 LDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSD---------DVKEKASLYVPM 294 ++D+V GV + +K+GAV ++ + ++ A P+ Sbjct: 213 -NADIVCVGVGKPD-LIKASMLKKGAVVVDIGINHLNDGRIVGDVDFTNAQKVAGFITPV 270 Query: 295 TGKV---TIAMLLRNMLRLVRN 313 V TI LL N L Sbjct: 271 PKGVGPMTIVSLLENTLIAFEK 292 >4B4V-A nrPDB Length = 303 Score = 249 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 65/323 (20%), Positives = 113/323 (34%), Gaps = 59/323 (18%) Query: 5 GRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESM 64 + +A+ ++ VE K G+ P+L L +D A+ Y + Sbjct: 23 ALVLDGRALAKQIEENLLVRVEALK-AKTGRTPILATILVGDDGASATYVRMKGNACRRV 81 Query: 65 GFR---YDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVE 121 G +L + L I + N + V+GI++ PV ++ + KDV+ Sbjct: 82 GMDSLKIELPQETTTEQLLAEIEKLNANPDVHGILLQHPVPAQIDERACFDAISLAKDVD 141 Query: 122 GLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCI 181 G+ + + + + TP I+ IL+ I + GK + Sbjct: 142 GVTCLGFGRMAMG---------EAAYGSATPAGIMTILKENNI---------EIAGKHAV 183 Query: 182 VINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKK 241 V+ RS I+G+P+A +L ATV L + Sbjct: 184 VVGRSAILGKPMAMMLLQANATVTICHSRTQN-------------------------LPE 218 Query: 242 CSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDV--------KEKASLYVP 293 +D+ I G + ++IK+GAV ++ V +E AS Y P Sbjct: 219 LVKQADI-IVGAVGKAELIQKDWIKQGAVVVDAGFHPRDGGGVGDIQLQGIEEIASAYTP 277 Query: 294 MTGKV---TIAMLLRNMLRLVRN 313 + G V TI L+R + Sbjct: 278 VPGGVGPMTITTLIRQTVEAAEK 300 >2C2Y-A nrPDB Length = 281 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 69/324 (21%), Positives = 107/324 (33%), Gaps = 61/324 (18%) Query: 5 GRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESM 64 + + ++ V G+ P L L +DP ++ Y + Sbjct: 3 AIMLDGKATRDEIFGDLKQRVAALDAA--GRTPGLGTILVGDDPGSQAYVRGKHADCAKV 60 Query: 65 GF---RYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVE 121 G R DL L E I + N + G +V P+ + + + V KD + Sbjct: 61 GITSIRRDLPADISTATLNETIDELNANPDCTGYIVQLPLPKHLDENAALERVDPAKDAD 120 Query: 122 GLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCI 181 GL+ L + LPCTP IV +L I + G + Sbjct: 121 GLHPTNLGRLVLGT---------PAPLPCTPRGIVHLLRRYDIS---------IAGAHVV 162 Query: 182 VINRSEIVGRPLAALLAN--DGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLL 239 VI R VGRPL LL + ATV + D L Sbjct: 163 VIGRGVTVGRPLGLLLTRRSENATVTLCH------------------------TGTRD-L 197 Query: 240 KKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK-------NFSDDVKEKASLYV 292 + +D+V+ V + + ++ GA I+ ++ + DV E A Sbjct: 198 PALTRQADIVVAAVG-VAHLLTADMVRPGAAVIDVGVSRTDDGLVGDVHPDVWELAGHVS 256 Query: 293 PMTGKV---TIAMLLRNMLRLVRN 313 P G V T A LL N++ L Sbjct: 257 PNPGGVGPLTRAFLLTNVVELAER 280 >3NGX-A nrPDB Length = 276 Score = 197 bits (501), Expect = 5e-51, Method: Composition-based stats. Identities = 60/320 (18%), Positives = 113/320 (35%), Gaps = 64/320 (20%) Query: 6 RTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMG 65 + + ++AE + +E +G P L ++ AA +YA + + +G Sbjct: 2 KILRGEEIAEKKAENLHGIIE-----RSGLEPSLKLIQIGDNEAASIYARAKIRRGKKIG 56 Query: 66 FRYDLRVIEDKD--FLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGL 123 DL +D L + I D +NGIM+ P+ + + + KDV+ L Sbjct: 57 IAVDLEKYDDISMKDLLKRIDDLAKDPQINGIMIENPLPKGFDYYEIVRNIPYYKDVDAL 116 Query: 124 NHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVI 183 + + N + ++P TP A++ I+++ + N ++ Sbjct: 117 SPYNQGLIALN---------REFLVPATPRAVIDIMDYYGYHEN-----------TVTIV 156 Query: 184 NRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCS 243 NRS +VGRPL+ +L N TV + + Sbjct: 157 NRSPVVGRPLSMMLLNRNYTVSVCHSKTKD-------------------------IGSMT 191 Query: 244 LDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFS--------DDVKEKASLYVPMT 295 S +V+ V + E + G+V I+ +D+ E P+ Sbjct: 192 RSSKIVVVAVGRPGFLNR-EMVTPGSVVIDVGINYVNDKVVGDANFEDLSEYVEAITPVP 250 Query: 296 GKV---TIAMLLRNMLRLVR 312 G V T +L N+++ Sbjct: 251 GGVGPITATNILENVVKAAE 270 >4PPM-A nrPDB Length = 861 Score = 41.4 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 34/220 (15%), Positives = 71/220 (32%), Gaps = 13/220 (5%) Query: 91 SVNGIMVYFPVFGN---AQDQYLQQVV---CKEKDVEGLNHVYYQNLYHNVRYLDKENRL 144 + G++ Y P+ + A + + V +E +G V V + Sbjct: 61 TCEGVIKYMPLVADEMLADARGIAARVVQGIEELAGDGAELVGLGGFTSIVGRRGEATAE 120 Query: 145 KSILPCTPLAIVKILEFLK-IYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGAT 203 KS +P T + K + R + ++ + L+ LL G + Sbjct: 121 KSPVPVTSGNSLTTYAGYKALMQIQSWLEIRPEEEPVAIVGYPGSICLALSRLLLAHGFS 180 Query: 204 VYSVDVNNIQKFTRGES-LKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPT 262 ++ + + S L H L EDL +C L + G + + Sbjct: 181 LHLLHRAGNHDRSELLSHLPEEYHSRVTLTSDPEDLYPRCKLFAAATSAGGVIDPARLQ- 239 Query: 263 EYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTIAM 302 G++ I+ A ++ + + + + + G A Sbjct: 240 ----PGSIFIDVALPRDIASETRPARDDILIIDGGCVTAT 275 >2EEZ-A nrPDB Length = 369 Score = 37.5 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 43/130 (33%), Gaps = 3/130 (2%) Query: 152 PLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNN 211 P + LE K +L G +VI VG A + GA V +DVN+ Sbjct: 140 PQVGAQFLEKPKGGRGVLLGGVPGVAPASVVILGGGTVGTNAAKIALGMGAQVTILDVNH 199 Query: 212 IQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYI---KEG 268 + + + + ++ L V+ + + KEG Sbjct: 200 KRLQYLDDVFGGRVITLTATEANIKKSVQHADLLIGAVLVPGAKAPKLVTRDMLSLMKEG 259 Query: 269 AVCINFACTK 278 AV ++ A + Sbjct: 260 AVIVDVAVDQ 269 >1MLD-A nrPDB Length = 314 Score = 36.4 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 31/97 (31%), Gaps = 2/97 (2%) Query: 178 KKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSED 237 K V+ S +G+PL+ LL N + L + G + Sbjct: 1 AKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGPE 60 Query: 238 LLKKCSLDSDVVI--TGVPSENYKFPTEYIKEGAVCI 272 L C DVV+ GVP + + A + Sbjct: 61 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 97 >1SMK-A nrPDB Length = 326 Score = 36.0 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 19/113 (16%), Positives = 38/113 (33%), Gaps = 9/113 (7%) Query: 177 GKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTR-GESLKLNKHHVEDLGEYS 235 G K ++ + +G+PLA L V + + ++ + G Sbjct: 8 GFKVAILGAAGGIGQPLAM-LMKMNPLVSVLHLYDVVNAPGVTADISHMDTGAVVRGFLG 66 Query: 236 EDLLKKCSLDSDVVIT--GVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKE 286 + L+ D++I GVP + + K IN K + + + Sbjct: 67 QQQLEAALTGMDLIIVPAGVPRKPGMTRDDLFK-----INAGIVKTLCEGIAK 114 >4WLE-A nrPDB Length = 340 Score = 35.6 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 31/97 (31%), Gaps = 2/97 (2%) Query: 178 KKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSED 237 K V+ S +G+PL+ LL N + L + G + Sbjct: 27 AKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPE 86 Query: 238 LLKKCSLDSDVVI--TGVPSENYKFPTEYIKEGAVCI 272 L C DVV+ GVP + + A + Sbjct: 87 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 123 >1O5I-A nrPDB Length = 249 Score = 35.2 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 39/95 (41%), Gaps = 8/95 (8%) Query: 163 KIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLK 222 KI+++ + K +V+ S +GR +A +L+ +GA V N E LK Sbjct: 5 KIHHHHHHMELGIRDKGVLVLAASRGIGRAVADVLSQEGAEVTICARNE-------ELLK 57 Query: 223 LNKHHVEDLGEYSE-DLLKKCSLDSDVVITGVPSE 256 + H + DLL + + D+++ Sbjct: 58 RSGHRYVVCDLRKDLDLLFEKVKEVDILVLNAGGP 92 >1DOH-A nrPDB Length = 283 Score = 35.2 bits (79), Expect = 0.040, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 19/47 (40%) Query: 160 EFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYS 206 ++ I L P+ L GK +V +GR +A L G V Sbjct: 12 KYDAIPGPLGPQSASLEGKVALVTGAGRGIGREMAMELGRRGCKVIV 58 >1LU9-A nrPDB Length = 287 Score = 34.5 bits (77), Expect = 0.061, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 40/112 (35%), Gaps = 2/112 (1%) Query: 163 KIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLK 222 + + G + GKK +V+ + VG AALLA +GA V + +S+ Sbjct: 105 GVALVVKAAGGSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVN 164 Query: 223 LNKHHVEDLGEYSEDLLKKCSLDSD--VVITGVPSENYKFPTEYIKEGAVCI 272 E ++D + ++ V G + E ++ I Sbjct: 165 KRFKVNVTAAETADDASRAEAVKGAHFVFTAGAIGLELLPQAAWQNESSIEI 216 >3W8F-A nrPDB Length = 260 Score = 33.7 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 27/79 (34%), Gaps = 2/79 (2%) Query: 175 LYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEY 234 L GKK +V + +G +A LA GA V + R S +K V+ Y Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVK--AYY 59 Query: 235 SEDLLKKCSLDSDVVITGV 253 L D + Sbjct: 60 LNADLSDAQATRDFIAKAA 78 >4JA0-A nrPDB Length = 425 Score = 33.7 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 28/88 (31%), Gaps = 2/88 (2%) Query: 12 KVAETFNTEIINNVEEYKKTHNGQGPLL--VGFLANNDPAAKMYATWTQKTSESMGFRYD 69 V + N K + P + + PA + + K + +G D Sbjct: 238 TVTAADLDTVKRNFAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVD 297 Query: 70 LRVIEDKDFLEEAIIQANGDDSVNGIMV 97 LRV EE + + +G +V Sbjct: 298 LRVTSAHKATEETLRIMQQYEDTHGALV 325 >3RWB-A nrPDB Length = 247 Score = 33.7 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 44/115 (38%), Gaps = 15/115 (13%) Query: 174 RLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESL----KLNKHHVE 229 RL GK +V ++ +G+ +AA LA DGATV D+N S+ + + Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADIS 62 Query: 230 DLGEYSE--DLLKKCSLDSDVVITGVPSENYKFPTE-----YIKEGAVCINFACT 277 D G ++ + D+++ + + + K I+ T Sbjct: 63 DPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRK----IIDVNLT 113 >4FS8-A nrPDB Length = 383 Score = 33.7 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 32/124 (25%), Positives = 43/124 (34%), Gaps = 5/124 (4%) Query: 199 NDGATVYSV-DVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSEN 257 N G+T V + T S L + E K + +D V+ Sbjct: 14 NGGSTPSIRDHVADYYGKTLQSSADLKTSACKLAAAVPESHRKILADIADEVLEKFYGCG 73 Query: 258 YKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTIAMLLRNMLRLVRN-VEL 316 P + EGA ++ C DV AS V GKV +L N L + R VE Sbjct: 74 STLPADGSLEGATVLDLGCGT--GRDVY-LASKLVGEHGKVIGVDMLDNQLEVARKYVEY 130 Query: 317 SKEK 320 EK Sbjct: 131 HAEK 134 >3WOH-A nrPDB Length = 251 Score = 32.9 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 28/86 (32%) Query: 175 LYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEY 234 L GK +V S +GR +A LA DGA V V V++ + Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRC 68 Query: 235 SEDLLKKCSLDSDVVITGVPSENYKF 260 ++ + V + + Sbjct: 69 DVSDAEQVTRCVKAVTADLGPVDILV 94 >3CKY-A nrPDB Length = 301 Score = 32.1 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 33/86 (38%), Gaps = 3/86 (3%) Query: 189 VGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDV 248 +G+P+A L +G TVY+ D+ + + + S D++ ++ + Sbjct: 15 MGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAAS-DIIFTSLPNAGI 73 Query: 249 VITGVPSENYKFPTEYIKEGAVCINF 274 V T + K G V ++ Sbjct: 74 VETVMNGPGGVLSA--CKAGTVIVDM 97 >4KDC-A nrPDB Length = 246 Score = 31.8 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 40/112 (35%), Gaps = 10/112 (8%) Query: 175 LYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEY 234 L+GKK + + G LA +A +GATV +D+ + V+ + E Sbjct: 61 LFGKKVLDVGCG---GGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQET 117 Query: 235 SEDLLKKCSLDSDVVI-------TGVPSENYKFPTEYIKEGAVCINFACTKN 279 E+ K + DVV P + + +K G +N Sbjct: 118 VEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRN 169 >1K24-A nrPDB Length = 253 Score = 31.4 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 10/70 (14%), Positives = 24/70 (34%), Gaps = 8/70 (11%) Query: 49 AAKMYATWTQKTSESMGFRYDLRVIEDKDFLEEA--------IIQANGDDSVNGIMVYFP 100 + + + K ++ +G R D+ ++ EA II D++ G Sbjct: 21 STRAFLKEKHKAAKHIGVRADIPFDANQGIRLEAGFGRSKKNIINLETDENKLGKTKNVK 80 Query: 101 VFGNAQDQYL 110 + + + Sbjct: 81 LPTGVPENRI 90 >4NBT-A nrPDB Length = 240 Score = 31.4 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 44/103 (42%), Gaps = 3/103 (2%) Query: 174 RLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNI-QKFTRGESLKLNKHHVEDLG 232 +L GK ++ ++ +G+ +A A +GA V + D+ ++ E + LN V + Sbjct: 3 KLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHPNVEGMYLNVTDVTGVE 62 Query: 233 EYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIK-EGAVCINF 274 ++ + ++ K D+++ + + + I+ Sbjct: 63 KFYQSVIDKY-GKIDILVNNAGITKDAMTRKMTEAQWDAVIDV 104 >6CI9-A nrPDB Length = 259 Score = 31.0 bits (68), Expect = 0.70, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 25/75 (33%) Query: 175 LYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEY 234 L G+ IV S+ +GR +A AN G V N L + V + Sbjct: 7 LEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRAD 66 Query: 235 SEDLLKKCSLDSDVV 249 D ++ V Sbjct: 67 VTDPEDARRTVAETV 81 >3DWF-A nrPDB Length = 276 Score = 30.6 bits (67), Expect = 0.83, Method: Composition-based stats. Identities = 16/41 (39%), Positives = 19/41 (46%) Query: 167 NLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSV 207 N L GKK IV S+ +GR +A LA GA V Sbjct: 1 NEKFRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVT 41 >3RAC-A nrPDB Length = 373 Score = 30.6 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 23/69 (33%), Gaps = 7/69 (10%) Query: 6 RTILASKVAETFNTEIINNVEEYK--KTHNGQGPLL-----VGFLANNDPAAKMYATWTQ 58 R A E+ ++ + G+ P+ + +DPA+ +A+ Sbjct: 84 RLFDGGGDAVALRPEMTPSIARMAAPRVAAGRTPIRWCYCERVYRRTDDPASLSWASGKA 143 Query: 59 KTSESMGFR 67 S +G Sbjct: 144 AESTQVGIE 152 >1HXH-A nrPDB Length = 253 Score = 30.6 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 35/96 (36%), Gaps = 5/96 (5%) Query: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFT----RGESLKLNKHHV 228 NRL GK +V + VG + LL +GA V D+N GE +H V Sbjct: 2 NRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDV 61 Query: 229 EDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEY 264 +++ ++ + V + P + Sbjct: 62 SSEADWTL-VMAAVQRRLGTLNVLVNNAGILLPGDM 96 >3QQW-A nrPDB Length = 332 Score = 30.6 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 27/81 (33%), Gaps = 7/81 (8%) Query: 240 KKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVT 299 D D+++ G + DV ++A L P+ V Sbjct: 95 PAWRQDVDIIVNGAGGRLAYITVPKATNSGQVAEV---IRYIGDVAKRAGLDKPVPVHVL 151 Query: 300 IAM--LLRNMLRLVR--NVEL 316 I LR++ ++ N+E+ Sbjct: 152 IETHGALRDVFQIAELPNIEV 172 >5PGZ-A nrPDB Length = 276 Score = 30.2 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 15/41 (36%), Positives = 19/41 (46%) Query: 167 NLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSV 207 N L GKK IV S+ +GR +A L+ GA V Sbjct: 8 NEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLT 48 >3RSH-A nrPDB Length = 251 Score = 29.8 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 21/39 (53%) Query: 166 NNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATV 204 +N + + L GK +V S +G+ +A LLA GA V Sbjct: 1 SNAMSQFMNLEGKVALVTGASRGIGKAIAELLAERGAKV 39 >4BVA-A nrPDB Length = 335 Score = 29.8 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 8/40 (20%), Positives = 18/40 (45%) Query: 239 LKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTK 278 +++ +DV+IT + E++K GA ++ Sbjct: 212 VQEAVTGADVIITVTMATEPILFGEWVKPGAHINAVGASR 251 >1BRW-A nrPDB Length = 433 Score = 29.8 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 32/94 (34%), Gaps = 1/94 (1%) Query: 216 TRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFA 275 T + + +D+G + L + DV+ V +K + +++G Sbjct: 339 TAAADGYVAEMAADDIGTAAMWLGAGRAKKEDVIDLAVGIVLHKKIGDRVQKGEALATIH 398 Query: 276 CTKNFSDDVKEKA-SLYVPMTGKVTIAMLLRNML 308 + DVKEK + V L+ + Sbjct: 399 SNRPDVLDVKEKIEAAIRLSPQPVARPPLIYETI 432 >2I99-A nrPDB Length = 312 Score = 29.8 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 27/58 (46%), Gaps = 4/58 (6%) Query: 239 LKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACT----KNFSDDVKEKASLYV 292 +++ +DV+IT + E++K GA + + D++ ++A LYV Sbjct: 190 VQEAVAGADVIITVTLATEPILFGEWVKPGAHINAVGASRPDWRELDDELMKEAVLYV 247 >3F9I-A nrPDB Length = 249 Score = 29.8 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 18/113 (15%), Positives = 41/113 (36%), Gaps = 5/113 (4%) Query: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLG 232 L GK ++ S +G +A LL G+ V + +N +K + + + +E Sbjct: 10 IDLTGKTSLITGASSGIGSAIARLLHKLGSKV-IISGSNEEKLKSLGNALKDNYTIEVCN 68 Query: 233 EYSEDL---LKKCSLDSDVVITGVPSENYKFPTEYIKEG-AVCINFACTKNFS 281 +++ L + + D+++ + + I+ NF Sbjct: 69 LANKEECSNLISKTSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFI 121 >4DIO-A nrPDB Length = 405 Score = 29.1 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 9/70 (12%) Query: 238 LLKKCSLDSDVVITGVPSENYKFPT-------EYIKEGAVCINFACTKNFSDDVKEKASL 290 L+ + D+VIT P + +K G+V ++ A + + + E A Sbjct: 268 LVAEHIAKQDIVITTALIPGRPAPRLVTREMLDSMKPGSVVVDLAVERGGNIEGAE-AGK 326 Query: 291 YVPMTGKVTI 300 + G V I Sbjct: 327 VTEV-GGVRI 335 >4Z53-A nrPDB Length = 742 Score = 29.1 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 26/178 (14%), Positives = 55/178 (30%), Gaps = 31/178 (17%) Query: 24 NVEEYKKTHNGQGPLLVGFLANNDPAAKMY--------ATWTQ-----KTSESMGFRYDL 70 +++ + G + D K Y K + ++ Sbjct: 446 KIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEI 505 Query: 71 RVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQN 130 +K L + I ++ V GI V + L+ + +KD + Y Sbjct: 506 PYEINKANLVKKIDDVRVNNKVAGIA---EVRDESDRDGLRIAIELKKDANTELVLNYLF 562 Query: 131 LYHNVRYLDKENRLKSILPCTPL--AIVKILEFLKIYNNLLPEGNRLYGKKCIVINRS 186 Y ++ ++ + +I TP IV IL + ++ +++ RS Sbjct: 563 KYTDL-QINYNFNMVAIDNFTPRQVGIVPILSSY------------IAHRREVILARS 607 >4TRR-A nrPDB Length = 269 Score = 29.1 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 44/117 (37%), Gaps = 16/117 (13%) Query: 175 LYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVN---------NIQKFTRGESLKLNK 225 L GK +V + +G+ +A LA GA V D+N I K Sbjct: 12 LNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGVAMD 71 Query: 226 HHVEDLGEYSEDLLKKCSLDSDVVITGV------PSENYKFPTEYIKEGAVCINFAC 276 E+ D + + D++++ P ENY F ++ K A+ ++ A Sbjct: 72 VTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSF-ADWKKMQAIHVDGAF 127 >3OML-A nrPDB Length = 613 Score = 29.1 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 30/102 (29%), Gaps = 25/102 (24%) Query: 177 GKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSE 236 G+ +V +GR A L A GA V D+ Sbjct: 19 GRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDG------------------- 59 Query: 237 DLLKKCSLDSDVVITGVPSENYKFPTEY--IKEGAVCINFAC 276 +D+V+ + + +Y + +GA I A Sbjct: 60 ----ASQRAADIVVDEIRKAGGEAVADYNSVIDGAKVIETAI 97 >5HUN-A nrPDB Length = 400 Score = 29.1 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 11/85 (12%), Positives = 22/85 (25%), Gaps = 6/85 (7%) Query: 111 QQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKI------LEFLKI 164 DV+G N + + C+P+ L K Sbjct: 13 INNTEPICDVKGFAPFSKDNGIRVGSRGHIFVIREPFVSCSPVGCRTFFLTQGSLLNDKH 72 Query: 165 YNNLLPEGNRLYGKKCIVINRSEIV 189 N + + + + + +S V Sbjct: 73 SNGTVKDRSPFRTLMSVEVGQSPNV 97 >2UVD-A nrPDB Length = 246 Score = 29.1 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 16/40 (40%), Positives = 19/40 (47%) Query: 175 LYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQK 214 L GK +V S +GR +A LA GA V N QK Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQK 41 >4MOW-A nrPDB Length = 256 Score = 29.1 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 174 RLYGKKCIVINRSEIVGRPLAALLANDGATVYS 206 +L GK IV S+ +G +A LA++GA V Sbjct: 11 KLAGKVAIVTGASKGIGAAIAKALADEGAAVVV 43 >5J3U-A nrPDB Length = 261 Score = 28.7 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 39/122 (31%), Gaps = 4/122 (3%) Query: 178 KKCIVINRSEIVGRPLAALLAND--GATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYS 235 + V+ + G ALL N ATV SV ++ + R + K Sbjct: 77 RVVKVVGPGDAFGE--LALLYNAPRAATVTSVSACDLWELGRDTFNAIVKDAATKRRSMY 134 Query: 236 EDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMT 295 + LK + + TE +GA + + V+E +++ Sbjct: 135 DSFLKSVHILDGMDAYERGKVADALRTEMFTDGAYIVRQGELGDVFYIVEEGSAVATKSF 194 Query: 296 GK 297 G Sbjct: 195 GP 196 >4KPF-A nrPDB Length = 496 Score = 28.7 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 26/178 (14%), Positives = 55/178 (30%), Gaps = 31/178 (17%) Query: 24 NVEEYKKTHNGQGPLLVGFLANNDPAAKMY--------ATWTQ-----KTSESMGFRYDL 70 +++ + G + D K Y K + ++ Sbjct: 200 KIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEI 259 Query: 71 RVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQN 130 +K L + I ++ V GI V + L+ + +KD + Y Sbjct: 260 PYEINKANLVKKIDDVRVNNKVAGIA---EVRDESDRDGLRIAIELKKDANTELVLNYLF 316 Query: 131 LYHNVRYLDKENRLKSILPCTPL--AIVKILEFLKIYNNLLPEGNRLYGKKCIVINRS 186 Y ++ ++ + +I TP IV IL + ++ +++ RS Sbjct: 317 KYTDL-QINYNFNMVAIDNFTPRQVGIVPILSSY------------IAHRREVILARS 361 >2PKW-A nrPDB Length = 260 Score = 28.7 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 26/88 (29%), Gaps = 9/88 (10%) Query: 96 MVYF-PVFGNAQDQYLQQV--------VCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKS 146 +VY P+F + Q L + V + D +GL Q V + Sbjct: 167 VVYLDPMFPHRQKSALVKKEMRVFQSLVGPDLDADGLLEPARQLATKRVVVKRPDYAPPL 226 Query: 147 ILPCTPLAIVKILEFLKIYNNLLPEGNR 174 TP AIV IY Sbjct: 227 ADVATPNAIVTKGHRFDIYAGTPLTELE 254 >4CQL-A nrPDB Length = 261 Score = 28.7 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 20/37 (54%) Query: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDV 209 NRL +V +GR ++ LA +GATV + D+ Sbjct: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL 43 >1HYE-A nrPDB Length = 313 Score = 28.7 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 34/103 (33%), Gaps = 8/103 (7%) Query: 178 KKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTR--------GESLKLNKHHVE 229 K +I S VG A LLA + V + + ++L + Sbjct: 1 MKVTIIGASGRVGSATALLLAKEPFMKDLVLIGREHSINKLEGLREDIYDALAGTRSDAN 60 Query: 230 DLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCI 272 E E+L D ++ +GVP + + K A + Sbjct: 61 IYVESDENLRIIDESDVVIITSGVPRKEGMSRMDLAKTNAKIV 103 >5CDY-A nrPDB Length = 244 Score = 28.3 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 15/29 (51%) Query: 176 YGKKCIVINRSEIVGRPLAALLANDGATV 204 GK +V S +GR +A LL GA V Sbjct: 4 EGKIALVTGASRGIGRAIAELLVERGACV 32 >4DMM-A nrPDB Length = 269 Score = 28.3 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 16/43 (37%) Query: 164 IYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYS 206 + L + +V S +GR +A LA GA V Sbjct: 15 VPRGSHMTALPLTDRIALVTGASRGIGRAIALELAAAGAKVAV 57 >5K1S-A nrPDB Length = 362 Score = 28.3 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 47/149 (31%), Gaps = 4/149 (2%) Query: 127 YYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRS 186 Y Q + V L R+ + LP A V ++ R G+ ++ S Sbjct: 138 YAQFMVAPVGGL---GRVPASLPWNEAATVCCTTGTAVHTVRTRGKVR-AGETVLITGAS 193 Query: 187 EIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDS 246 VG L DGA V +V + + E+ L S+ + Sbjct: 194 GGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFASDVRKRTQGAGV 253 Query: 247 DVVITGVPSENYKFPTEYIKEGAVCINFA 275 DV + V S + + + G + Sbjct: 254 DVAVEIVGSATFDQTLKSMAPGGRVVVVG 282 >4E6P-A nrPDB Length = 259 Score = 28.3 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 29/69 (42%), Gaps = 1/69 (1%) Query: 174 RLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGE 233 RL GK ++ + +GR A +GATV D+ +I++ + + + + Sbjct: 5 RLEGKSALITGSARGIGRAFAEAYVREGATVAIADI-DIERARQAAAEIGPAAYAVQMDV 63 Query: 234 YSEDLLKKC 242 +D + Sbjct: 64 TRQDSIDAA 72 >3M84-A nrPDB Length = 350 Score = 28.3 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 21/126 (16%), Positives = 45/126 (35%), Gaps = 11/126 (8%) Query: 161 FLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGES 220 + NL + +V+ +P+ L D +D +++ +G S Sbjct: 79 MCGKFENLGYDLFSAATNDIVVMGA-----KPITFL---DYVAHDKLDPAIMEELVKGMS 130 Query: 221 LKLNKHHVEDLGEYSEDL---LKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACT 277 + V +G + ++ + +D VITG+ E IKEG + + + Sbjct: 131 KACAECGVSLVGGETAEMPGVYQAGEIDMVGVITGIVDRKRIINGENIKEGDIVFGLSSS 190 Query: 278 KNFSDD 283 ++ Sbjct: 191 GLHTNG 196 >3WTC-A nrPDB Length = 262 Score = 27.9 bits (60), Expect = 5.3, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 20/37 (54%) Query: 175 LYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNN 211 L GK V ++ +G+ +A LA DGA V +DV Sbjct: 6 LSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQ 42 >3D3W-A nrPDB Length = 244 Score = 27.9 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 23/60 (38%) Query: 175 LYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEY 234 L G++ +V + +GR L GA V +V + + DLG++ Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDW 64 >5XAN-A nrPDB Length = 750 Score = 27.9 bits (60), Expect = 6.0, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 31/96 (32%), Gaps = 6/96 (6%) Query: 186 SEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLD 245 + V R +A +L + +V +++ + + + +LK +L Sbjct: 197 GKNVNRLMAVVLDDQIQSVATINQRLFRDIQISGNFTPEEASQLAC------VLKSGALP 250 Query: 246 SDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFS 281 +V S + I+ GA+ F Sbjct: 251 IKIVTAAERSIGPSLGADAIRSGAIAALVGIGLVFV 286 >2X9N-A nrPDB Length = 288 Score = 27.5 bits (59), Expect = 7.3, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 18/39 (46%) Query: 168 LLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYS 206 L+P G+ + +V ++ +GR +A L G V Sbjct: 14 LVPRGSHMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVI 52 >3FTP-A nrPDB Length = 270 Score = 27.1 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 11/25 (44%), Positives = 13/25 (52%) Query: 180 CIVINRSEIVGRPLAALLANDGATV 204 IV S +GR +A LA GA V Sbjct: 31 AIVTGASRGIGRAIALELARRGAMV 55 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.117 0.292 Lambda K H 0.267 0.0361 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,364,544 Number of Sequences: 36641 Number of extensions: 391462 Number of successful extensions: 1494 Number of sequences better than 10.0: 73 Number of HSP's better than 10.0 without gapping: 72 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 1307 Number of HSP's gapped (non-prelim): 115 length of query: 320 length of database: 10,336,785 effective HSP length: 97 effective length of query: 223 effective length of database: 6,782,608 effective search space: 1512521584 effective search space used: 1512521584 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.5 bits)