BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q01650 (507 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6IRS-B nrPDB 1013 0.0 6F2W-A nrPDB 179 2e-45 6F34-A nrPDB 96 5e-20 3GIA-A nrPDB 62 6e-10 3NCY-A nrPDB 61 1e-09 5J4I-A nrPDB 59 4e-09 4DJI-A nrPDB 28 6.4 6D9T-A nrPDB 28 7.0 6AGB-I nrPDB 28 7.1 >6IRS-B nrPDB Length = 527 Score = 1013 bits (2618), Expect = 0.0, Method: Compositional matrix adjust. Identities = 505/506 (99%), Positives = 505/506 (99%) Query: 2 AGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVG 61 AGAGPKRRALAAPAAEEKEEAREKMLAAKSADGS PAGEGEGVTLQRNITLLNGVAIIVG Sbjct: 22 AGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSEPAGEGEGVTLQRNITLLNGVAIIVG 81 Query: 62 TIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYML 121 TIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYML Sbjct: 82 TIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYML 141 Query: 122 EVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLL 181 EVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLL Sbjct: 142 EVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLL 201 Query: 182 LTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVG 241 LTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVG Sbjct: 202 LTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVG 261 Query: 242 NIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLS 301 NIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLS Sbjct: 262 NIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLS 321 Query: 302 TEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPS 361 TEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPS Sbjct: 322 TEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPS 381 Query: 362 ILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421 ILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR Sbjct: 382 ILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 441 Query: 422 KPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKNK 481 KPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKNK Sbjct: 442 KPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKNK 501 Query: 482 PKWLLQGIFSTTVLCQKLMQVVPQET 507 PKWLLQGIFSTTVLCQKLMQVVPQET Sbjct: 502 PKWLLQGIFSTTVLCQKLMQVVPQET 527 >6F2W-A nrPDB Length = 444 Score = 179 bits (455), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 134/436 (30%), Positives = 222/436 (50%), Gaps = 18/436 (4%) Query: 47 QRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAEL 106 + ++ + + ++VGT+IG+GIF PT V AG+PGL L+ W G+ +I G L AE+ Sbjct: 1 MKEVSGITALTVVVGTVIGAGIFFKPTAVYGAAGAPGLGLLAWFVAGIITIAGGLTVAEI 60 Query: 107 GTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLK--PLFPTC 164 GT ++GG Y+ +VYG FL W +++I P++ +A++FAT + L + Sbjct: 61 GTIYPQTGGMMIYLEKVYGRWLGFLVGWAQMVIYYPANIAALAIIFATQFVNLFALSDST 120 Query: 165 PVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDV 224 VP A L + L VN K + +Q KL+ L +II+ G + G G V Sbjct: 121 IVPT------AILTSIFLMGVNFLGTKYSGWIQTLATILKLIPLVVIIVAGLLYPG-GGV 173 Query: 225 SNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPI 284 L P FS E T + + AL + LFAY GW + + EM NP + LP II L I Sbjct: 174 IRLVP-FSVE-THPVLTSFGSALIATLFAYDGWINVGTLAGEMKNPGKMLPKVIIGGLSI 231 Query: 285 VTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL--GVMSWIIPVFVGLSCFGSVNGS 342 V VY+LTN+AY L + Q+ ++ A + HL G+ S ++ + + +S FG +NG Sbjct: 232 VMAVYLLTNIAYLFVLDSSQLAGTDTPAALVAS-HLFEGIGSKLVTIGILISVFGGINGY 290 Query: 343 LFTSSRLFFVGSREGHLP--SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF 400 + + R+ + + + LP + I+P+ P+ + + ++ + + + Sbjct: 291 IISGLRVPYALATQKMLPFSDWFARINPKTNLPINGGLVMLGIAIVMILTGQFNQLTDLI 350 Query: 401 SFFNWLCVALAIIGMIWLRHRKPELERPIKVNL--ALPVFFILACLFLIAVSFWKTPVEC 458 F W + L I +I LR +P++ERP +V +P+ I+ L++I + P Sbjct: 351 VFVIWFFITLTFIAVIILRKTQPDIERPYRVPFYPVIPLIAIIGGLYIIFNTLIVQPKNA 410 Query: 459 GIGFTIILSGLPVYFF 474 IG + L G+P+YF+ Sbjct: 411 FIGILLTLIGIPIYFY 426 >6F34-A nrPDB Length = 461 Score = 95.5 bits (236), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 106/421 (25%), Positives = 183/421 (43%), Gaps = 49/421 (11%) Query: 78 EAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIEL 137 E P L L + G+ + ALCYAE +T+ SG Y Y +G L A++ W +L Sbjct: 55 EHAGPALVLS-FILSGLACVFAALCYAEFASTVPVSGSAYTYSYATFGELIAWILGW-DL 112 Query: 138 LIIRPSSQYIVALVFATYLLKPL------FPTC------PVPEEAAKLVACLCVLLLTAV 185 ++ + VA+ ++ Y L P P L A + VL +T + Sbjct: 113 ILEYGVASSAVAVGWSGYFQGLLSGFGIELPKALTSAYDPAKGTFIDLPAIIIVLFITFL 172 Query: 186 NCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVL 245 K + R A K+ + L + +G + + + P + F G + Sbjct: 173 LNLGAKKSARFNAVIVAIKVAVVLLFLAVGVWYVKPENWTPFMP-YGFSGVATGAATV-- 229 Query: 246 ALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQM 305 FAY G++ ++ EE+ NP R++P+ II+SL + TL+Y+ +L + EQ+ Sbjct: 230 -----FFAYIGFDAVSTAAEEVRNPQRDMPIGIIVSLLVCTLLYIAVSLVLTGIVPYEQL 284 Query: 306 LSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNG-------SLFTSSRLFFVGSREGH 358 VA H W+ G G++ G S++ +RLF+ SR+G Sbjct: 285 NVKNPVAFALNYIH---QDWV----AGFISLGAIAGITTVLLVSMYGQTRLFYAISRDGL 337 Query: 359 LPSILSMIHPQLLTPVPSLVFTCVMTLLYAFS---KDIFSVINFFSFFNWLCVALAIIGM 415 LP + + I P P + T ++A + + N + F ++ V+ IG+ Sbjct: 338 LPKVFARISPTRQVPYVNTWLTGAAVAVFAGIIPLNKLAELTNIGTLFAFITVS---IGV 394 Query: 416 IWLRHRKPELERPIKVNL--ALPVFFILACLFLIAVSFWKTPVECGIGF-TIILSGLPVY 472 + LR +P+L+R +V +P+ +L C +L+ + P IGF + +L GL +Y Sbjct: 395 LVLRKTQPDLKRAFRVPFVPVVPILAVLFCGYLVL----QLPAMTWIGFVSWLLIGLVIY 450 Query: 473 F 473 F Sbjct: 451 F 451 >3GIA-A nrPDB Length = 444 Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 84/327 (25%), Positives = 149/327 (45%), Gaps = 35/327 (10%) Query: 47 QRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAEL 106 + ++L V++ VG +IG+ IF + GV + L + G+++++ A Y +L Sbjct: 5 NKKLSLWEAVSMAVGVMIGASIF-SIFGVGAKIAGRNLP-ETFILSGIYALLVAYSYTKL 62 Query: 107 GTTISKSGGDYAYMLE------VYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL 160 G I + G A++ + + G+L + LW+ +I S + A FA Y L PL Sbjct: 63 GAKIVSNAGPIAFIHKAIGDNIITGALS--ILLWMSYVI----SIALFAKGFAGYFL-PL 115 Query: 161 FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIG 220 P+ + V TA+N + KA R + KLL L L I G + I Sbjct: 116 I-NAPINTFNIAITEIGIVAFFTALNFFGSKAVGRAEFFIVLVKLLILGLFIFAGLITIH 174 Query: 221 KGDV-SNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAII 279 V +L P+ V ++ A +Y G+ + +E + NP +N+P AI Sbjct: 175 PSYVIPDLAPS--------AVSGMIFASAIFFLSYMGFGVITNASEHIENPKKNVPRAIF 226 Query: 280 ISLPIVTLVYVLTNLAYFTTLSTEQML--SSEAVAVD----FGNYHLGVMSWIIPVFVGL 333 IS+ IV VYV ++ L ++++ S A+AV GN LG + +I + Sbjct: 227 ISILIVMFVYVGVAISAIGNLPIDELIKASENALAVAAKPFLGN--LGFL--LISIGALF 282 Query: 334 SCFGSVNGSLFTSSRLFFVGSREGHLP 360 S ++N +++ + + + +++G LP Sbjct: 283 SISSAMNATIYGGANVAYSLAKDGELP 309 >3NCY-A nrPDB Length = 445 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 84/343 (24%), Positives = 142/343 (41%), Gaps = 28/343 (8%) Query: 58 IIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDY 117 ++ G I+GSG+F+ P + A + G+A+ W + ++ ++ YA++ + GG Y Sbjct: 18 MVSGNIMGSGVFLLPANL---AATGGIAIYGWLVTIIGALALSMVYAKMSSLDPSPGGSY 74 Query: 118 AYMLEVYGSLPAF---LKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLV 174 AY +G + + W+ I I +V L FP P + Sbjct: 75 AYARRCFGPFLGYQTNVLYWLACWI-----GNIAMVVIGVGYLSYFFPILKDPL--VLTL 127 Query: 175 ACLCVL-LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIG----KGDVSNLDP 229 C+ VL + +N K TRVQ A LAL+ ++G G KG+ Sbjct: 128 TCVAVLWIFVLLNIVGPKMITRVQ-----AVATVLALVPIVGIAVFGWFWFKGETYMAAW 182 Query: 230 NFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVY 289 N S T G I L L+++ G + + NP RN+P+A I + I + Y Sbjct: 183 NVSGMNT---FGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIAAVCY 239 Query: 290 VLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS-CFGSVNGSLFTSSR 348 VL+ A + + S + D LG + I F + C GS+ G + + Sbjct: 240 VLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSLGGWTLLAGQ 299 Query: 349 LFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSK 391 + +G P I + ++ + TPV L+ V+ ++ FS Sbjct: 300 TAKAAADDGLFPPIFARVN-KAGTPVAGLLIVGVLMTIFQFSS 341 >5J4I-A nrPDB Length = 453 Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 87/347 (25%), Positives = 143/347 (41%), Gaps = 36/347 (10%) Query: 58 IIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGAL----CYAELGTTISKS 113 ++ G I+GSG+F+ P + A + G+A+ W + +I+GAL YA++ Sbjct: 18 MVSGNIMGSGVFLLPANL---ASTGGIAIYGW----LVTIIGALGLSMVYAKMSFLDPSP 70 Query: 114 GGDYAYMLEVYGSLPAF---LKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEA 170 GG YAY +G + + W+ I I +V L FP P Sbjct: 71 GGSYAYARRCFGPFLGYQTNVLYWLACWI-----GNIAMVVIGVGYLSYFFPILKDPL-- 123 Query: 171 AKLVACLCVL-LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIG----KGDVS 225 + C+ VL + +N K TRVQ A LALI ++G G +G+ Sbjct: 124 VLTITCVVVLWIFVLLNIVGPKMITRVQ-----AVATVLALIPIVGIAVFGWFWFRGETY 178 Query: 226 NLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIV 285 N S GT G I L L+++ G + + NP RN+P+A I + I Sbjct: 179 MAAWNVSGLGT---FGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIA 235 Query: 286 TLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS-CFGSVNGSLF 344 + YVL+ A + + S + D LG + I F + C GS+ G Sbjct: 236 AVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSLGGWTL 295 Query: 345 TSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSK 391 + + + +G P I + ++ + TPV L+ ++ ++ S Sbjct: 296 LAGQTAKAAADDGLFPPIFARVN-KAGTPVAGLIIVGILMTIFQLSS 341 >4DJI-A nrPDB Length = 511 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 28/195 (14%) Query: 101 LCYAELGTTIS-KSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFA----TY 155 LC AE+ T + GG +A++ G F + L I + +I L F +Y Sbjct: 59 LCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQI--AIGFIPMLYFVLGALSY 116 Query: 156 LLK-PLFPTCPVPEEAAKLVACLCVLLLTAVNCYS-VKAATRVQD-AFAAAKLLALALII 212 +LK P P+ K +A L +L A+ + K R+ F A LL ++I Sbjct: 117 ILKWPALNEDPI----TKTIAALIILWALALTQFGGTKYTARIAKVGFFAGILLPAFILI 172 Query: 213 LLGFVQIGKG-------DVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTE 265 L + + G D P+FS GT ++ + + +Y G Sbjct: 173 ALAAIYLHSGAPVAIEMDSKTFFPDFSKVGT-------LVVFVAFILSYMGVEASATHVN 225 Query: 266 EMINPYRNLPLAIII 280 EM NP R+ PLA+++ Sbjct: 226 EMSNPGRDYPLAMLL 240 >6D9T-A nrPDB Length = 400 Score = 28.5 bits (62), Expect = 7.0, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 1/59 (1%) Query: 331 VGLSCFGSVNGSLFTSSRLFFVGSREGH-LPSILSMIHPQLLTPVPSLVFTCVMTLLYA 388 +G++C+ S+ GS ++ L + GH + I S I ++ P+P+++F V YA Sbjct: 23 IGITCYPSMGGSGIIATELGIKLAERGHEVHFITSNIPFRIRKPLPNMIFHQVEVNQYA 81 >6AGB-I nrPDB Length = 293 Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust. Identities = 18/39 (46%), Positives = 22/39 (56%), Gaps = 1/39 (2%) Query: 95 FSIVGALCYAELGTTISKSGGDYAYMLEVYGS-LPAFLK 132 F IV AL +E G T+S + D + YGS LP FLK Sbjct: 104 FDIVAALPISEKGLTLSTTNLDIDLLTFQYGSRLPTFLK 142 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6IRS-B nrPDB 650 0.0 6F2W-A nrPDB 366 e-101 6F34-A nrPDB 315 2e-86 3NCY-A nrPDB 270 9e-73 5J4I-A nrPDB 270 1e-72 3GIA-A nrPDB 224 6e-59 Sequences not found previously or not previously below threshold: 4DJI-A nrPDB 80 3e-15 6BWF-A nrPDB 34 0.12 6DG4-A nrPDB 29 4.9 6HUO-B nrPDB 29 6.6 4COF-A nrPDB 28 9.3 >6IRS-B nrPDB Length = 527 Score = 650 bits (1677), Expect = 0.0, Method: Composition-based stats. Identities = 505/506 (99%), Positives = 505/506 (99%) Query: 2 AGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVG 61 AGAGPKRRALAAPAAEEKEEAREKMLAAKSADGS PAGEGEGVTLQRNITLLNGVAIIVG Sbjct: 22 AGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSEPAGEGEGVTLQRNITLLNGVAIIVG 81 Query: 62 TIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYML 121 TIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYML Sbjct: 82 TIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYML 141 Query: 122 EVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLL 181 EVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLL Sbjct: 142 EVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLL 201 Query: 182 LTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVG 241 LTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVG Sbjct: 202 LTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVG 261 Query: 242 NIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLS 301 NIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLS Sbjct: 262 NIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLS 321 Query: 302 TEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPS 361 TEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPS Sbjct: 322 TEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPS 381 Query: 362 ILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421 ILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR Sbjct: 382 ILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 441 Query: 422 KPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKNK 481 KPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKNK Sbjct: 442 KPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKNK 501 Query: 482 PKWLLQGIFSTTVLCQKLMQVVPQET 507 PKWLLQGIFSTTVLCQKLMQVVPQET Sbjct: 502 PKWLLQGIFSTTVLCQKLMQVVPQET 527 >6F2W-A nrPDB Length = 444 Score = 366 bits (939), Expect = e-101, Method: Composition-based stats. Identities = 129/433 (29%), Positives = 219/433 (50%), Gaps = 12/433 (2%) Query: 47 QRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAEL 106 + ++ + + ++VGT+IG+GIF PT V AG+PGL L+ W G+ +I G L AE+ Sbjct: 1 MKEVSGITALTVVVGTVIGAGIFFKPTAVYGAAGAPGLGLLAWFVAGIITIAGGLTVAEI 60 Query: 107 GTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPV 166 GT ++GG Y+ +VYG FL W +++I P++ +A++FAT + + Sbjct: 61 GTIYPQTGGMMIYLEKVYGRWLGFLVGWAQMVIYYPANIAALAIIFATQFVNLF----AL 116 Query: 167 PEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSN 226 + A L + L VN K + +Q KL+ L +II+ G + G G V Sbjct: 117 SDSTIVPTAILTSIFLMGVNFLGTKYSGWIQTLATILKLIPLVVIIVAGLLYPG-GGVIR 175 Query: 227 LDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVT 286 L P FS E T + + AL + LFAY GW + + EM NP + LP II L IV Sbjct: 176 LVP-FSVE-THPVLTSFGSALIATLFAYDGWINVGTLAGEMKNPGKMLPKVIIGGLSIVM 233 Query: 287 LVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL-GVMSWIIPVFVGLSCFGSVNGSLFT 345 VY+LTN+AY L + Q+ ++ A ++ G+ S ++ + + +S FG +NG + + Sbjct: 234 AVYLLTNIAYLFVLDSSQLAGTDTPAALVASHLFEGIGSKLVTIGILISVFGGINGYIIS 293 Query: 346 SSRLFFVGSREGHLP--SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFF 403 R+ + + + LP + I+P+ P+ + + ++ + + + F Sbjct: 294 GLRVPYALATQKMLPFSDWFARINPKTNLPINGGLVMLGIAIVMILTGQFNQLTDLIVFV 353 Query: 404 NWLCVALAIIGMIWLRHRKPELERPIKVNL--ALPVFFILACLFLIAVSFWKTPVECGIG 461 W + L I +I LR +P++ERP +V +P+ I+ L++I + P IG Sbjct: 354 IWFFITLTFIAVIILRKTQPDIERPYRVPFYPVIPLIAIIGGLYIIFNTLIVQPKNAFIG 413 Query: 462 FTIILSGLPVYFF 474 + L G+P+YF+ Sbjct: 414 ILLTLIGIPIYFY 426 >6F34-A nrPDB Length = 461 Score = 315 bits (808), Expect = 2e-86, Method: Composition-based stats. Identities = 113/451 (25%), Positives = 200/451 (44%), Gaps = 35/451 (7%) Query: 41 GEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGA 100 +G +L++ + + + +G IIG+GIFV E P L L + G+ + A Sbjct: 18 AKGASLRKELGAFDLTMLGIGAIIGTGIFVLTGVAAAEHAGPALVLS-FILSGLACVFAA 76 Query: 101 LCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL 160 LCYAE +T+ SG Y Y +G L A++ W +L++ + VA+ ++ Y L Sbjct: 77 LCYAEFASTVPVSGSAYTYSYATFGELIAWILGW-DLILEYGVASSAVAVGWSGYFQGLL 135 Query: 161 ------FPTC------PVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLAL 208 P P L A + VL +T + K + R A K+ + Sbjct: 136 SGFGIELPKALTSAYDPAKGTFIDLPAIIIVLFITFLLNLGAKKSARFNAVIVAIKVAVV 195 Query: 209 ALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMI 268 L + +G + + + P + F G + FAY G++ ++ EE+ Sbjct: 196 LLFLAVGVWYVKPENWTPFMP-YGFSGVATGAATV-------FFAYIGFDAVSTAAEEVR 247 Query: 269 NPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIP 328 NP R++P+ II+SL + TL+Y+ +L + EQ+ VA H ++ I Sbjct: 248 NPQRDMPIGIIVSLLVCTLLYIAVSLVLTGIVPYEQLNVKNPVAFALNYIHQDWVAGFIS 307 Query: 329 VFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYA 388 + + S++ +RLF+ SR+G LP + + I P P + T ++A Sbjct: 308 LGAIAGITTVLLVSMYGQTRLFYAISRDGLLPKVFARISPTRQVPYVNTWLTGAAVAVFA 367 Query: 389 FS---KDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLA--LPVFFILAC 443 + + N + F ++ V+ IG++ LR +P+L+R +V +P+ +L C Sbjct: 368 GIIPLNKLAELTNIGTLFAFITVS---IGVLVLRKTQPDLKRAFRVPFVPVVPILAVLFC 424 Query: 444 LFLIAVSFWKTPVECGIGF-TIILSGLPVYF 473 +L+ + P IGF + +L GL +YF Sbjct: 425 GYLVL----QLPAMTWIGFVSWLLIGLVIYF 451 >3NCY-A nrPDB Length = 445 Score = 270 bits (691), Expect = 9e-73, Method: Composition-based stats. Identities = 97/433 (22%), Positives = 171/433 (39%), Gaps = 37/433 (8%) Query: 49 NITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGT 108 + L+ ++ G I+GSG+F+ P + A + G+A+ W + ++ ++ YA++ + Sbjct: 9 KVGLIPVTLMVSGNIMGSGVFLLPANL---AATGGIAIYGWLVTIIGALALSMVYAKMSS 65 Query: 109 TISKSGGDYAYMLEVYGSLPAF---LKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCP 165 GG YAY +G + + W+ I I +V L FP Sbjct: 66 LDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWI-----GNIAMVVIGVGYLSYFFPILK 120 Query: 166 VPEEAAKLVACLCVL-LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIG---- 220 P + C+ VL + +N K TRVQ A LAL+ ++G G Sbjct: 121 DPL--VLTLTCVAVLWIFVLLNIVGPKMITRVQ-----AVATVLALVPIVGIAVFGWFWF 173 Query: 221 KGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIII 280 KG+ N S T G I L L+++ G + + NP RN+P+A I Sbjct: 174 KGETYMAAWNVSGMNT---FGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIG 230 Query: 281 SLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS-CFGSV 339 + I + YVL+ A + + S + D LG + I F + C GS+ Sbjct: 231 GVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSL 290 Query: 340 NGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFS-------KD 392 G + + + +G P I + ++ + TPV L+ V+ ++ FS K+ Sbjct: 291 GGWTLLAGQTAKAAADDGLFPPIFARVN-KAGTPVAGLLIVGVLMTIFQFSSMSPNAAKE 349 Query: 393 IFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFW 452 V + F + ++ L H RP+ L + + C++ + S Sbjct: 350 FGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPLY--LLITFVAFVYCIWAVIGSGA 407 Query: 453 KTPVECGIGFTII 465 K + + +I Sbjct: 408 KEVMWSFVTLMVI 420 >5J4I-A nrPDB Length = 453 Score = 270 bits (689), Expect = 1e-72, Method: Composition-based stats. Identities = 98/433 (22%), Positives = 170/433 (39%), Gaps = 37/433 (8%) Query: 49 NITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGT 108 + L+ ++ G I+GSG+F+ P + A + G+A+ W + ++ ++ YA++ Sbjct: 9 KVGLIPVTLMVSGNIMGSGVFLLPANL---ASTGGIAIYGWLVTIIGALGLSMVYAKMSF 65 Query: 109 TISKSGGDYAYMLEVYGSLPAF---LKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCP 165 GG YAY +G + + W+ I I +V L FP Sbjct: 66 LDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWI-----GNIAMVVIGVGYLSYFFPILK 120 Query: 166 VPEEAAKLVACLCVL-LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIG---- 220 P + C+ VL + +N K TRVQ A LALI ++G G Sbjct: 121 DPL--VLTITCVVVLWIFVLLNIVGPKMITRVQ-----AVATVLALIPIVGIAVFGWFWF 173 Query: 221 KGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIII 280 +G+ N S GT G I L L+++ G + + NP RN+P+A I Sbjct: 174 RGETYMAAWNVSGLGT---FGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIG 230 Query: 281 SLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS-CFGSV 339 + I + YVL+ A + + S + D LG + I F + C GS+ Sbjct: 231 GVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSL 290 Query: 340 NGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFS-------KD 392 G + + + +G P I + ++ + TPV L+ ++ ++ S K+ Sbjct: 291 GGWTLLAGQTAKAAADDGLFPPIFARVN-KAGTPVAGLIIVGILMTIFQLSSISPNATKE 349 Query: 393 IFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFW 452 V + F + ++ L H RP LA+ L C++ + S Sbjct: 350 FGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARP--AYLAVTTIAFLYCIWAVVGSGA 407 Query: 453 KTPVECGIGFTII 465 K + + +I Sbjct: 408 KEVMWSFVTLMVI 420 >3GIA-A nrPDB Length = 444 Score = 224 bits (571), Expect = 6e-59, Method: Composition-based stats. Identities = 86/371 (23%), Positives = 158/371 (42%), Gaps = 20/371 (5%) Query: 47 QRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAEL 106 + ++L V++ VG +IG+ IF + GV + L + G+++++ A Y +L Sbjct: 5 NKKLSLWEAVSMAVGVMIGASIF-SIFGVGAKIAGRNLP-ETFILSGIYALLVAYSYTKL 62 Query: 107 GTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPV 166 G I + G A++ + G L I L + S + A FA Y L + P+ Sbjct: 63 GAKIVSNAGPIAFIHKAIGDNIITGALSILLWMSYVISIALFAKGFAGYFLPLI--NAPI 120 Query: 167 PEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDV-S 225 + V TA+N + KA R + KLL L L I G + I V Sbjct: 121 NTFNIAITEIGIVAFFTALNFFGSKAVGRAEFFIVLVKLLILGLFIFAGLITIHPSYVIP 180 Query: 226 NLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIV 285 +L P+ V ++ A +Y G+ + +E + NP +N+P AI IS+ IV Sbjct: 181 DLAPS--------AVSGMIFASAIFFLSYMGFGVITNASEHIENPKKNVPRAIFISILIV 232 Query: 286 TLVYVLTNLAYFTTLSTEQML--SSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSL 343 VYV ++ L ++++ S A+AV + + +I + S ++N ++ Sbjct: 233 MFVYVGVAISAIGNLPIDELIKASENALAVAAKPFLGNLGFLLISIGALFSISSAMNATI 292 Query: 344 FTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAF---SKDIFSVINFF 400 + + + + +++G LP T L T + +L+A + + S+ + Sbjct: 293 YGGANVAYSLAKDGELPEFFERKVWFKST--EGLYITSALGVLFALLFNMEGVASITSAV 350 Query: 401 SFFNWLCVALA 411 +L V L+ Sbjct: 351 FMVIYLFVILS 361 >4DJI-A nrPDB Length = 511 Score = 79.7 bits (195), Expect = 3e-15, Method: Composition-based stats. Identities = 70/383 (18%), Positives = 135/383 (35%), Gaps = 34/383 (8%) Query: 76 LKEAGSPGLALVVWAACG--VFSIVGALCYAELGTTIS-KSGGDYAYMLEVYGSLPAFLK 132 + G +LV + G ++ I LC AE+ T + GG +A++ G F Sbjct: 32 YPTFATSGFSLVFFLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAA 91 Query: 133 LWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKA 192 + L I ++ V +P + A + + L K Sbjct: 92 ISFGYLQIAIGFIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKY 151 Query: 193 ATRVQDA-FAAAKLLALALIILLGFVQIGKG-------DVSNLDPNFSFEGTKLDVGNIV 244 R+ F A LL ++I L + + G D P+FS GT + Sbjct: 152 TARIAKVGFFAGILLPAFILIALAAIYLHSGAPVAIEMDSKTFFPDFSKVGTLVVF---- 207 Query: 245 LALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQ 304 + + +Y G EM NP R+ PLA+++ + + + L+ + + Sbjct: 208 ---VAFILSYMGVEASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNE 264 Query: 305 MLSSEAVAVDFGNY------HLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGH 358 + S V F + +I + L + + SR +V +++ Sbjct: 265 INLSAGVMQTFTVLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNL 324 Query: 359 LPSILSMIHPQLLTPV----PSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALA--- 411 LP+ + ++ + PV LV T + ++ + ++ + + + L Sbjct: 325 LPAAFAKMN-KNGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYF 383 Query: 412 --IIGMIWLRHRKPELERPIKVN 432 IG I L + P+L+R + Sbjct: 384 MLFIGYIVLVLKHPDLKRTFNIP 406 >6BWF-A nrPDB Length = 954 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 36/264 (13%), Positives = 79/264 (29%), Gaps = 45/264 (17%) Query: 180 LLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNF--SFEGTK 237 + ++ S K D F + +A+ +G G N+ +++ Sbjct: 558 VFMSEAGKISQKIKVWFSDYFNVSDTIAIISF------FVGFGLRFGAKWNYINAYDNHV 611 Query: 238 LDVGNIVLALYSGLF--AYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLA 295 G ++ L + + +N P ++I + + Y++ +A Sbjct: 612 FVAGRLIYCLNIIFWYVRLLDFLAVNQQAG---------PYVMMIGKMVANMFYIVVIMA 662 Query: 296 YFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVG-- 353 +LS H SW + + + + + Sbjct: 663 LV-------LLSFGVPRKAILYPH-EEPSWSLAKDIVFHPY-----WMIFGEVYAYEIDV 709 Query: 354 -SREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAI 412 + + LP+I P T + +Y F + I V +FFN + + + Sbjct: 710 CANDSTLPTICG----------PGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKA 759 Query: 413 IGMIWLRHRKPELERPIKVNLALP 436 I I ++++ LP Sbjct: 760 ISNIVWKYQRYHFIMAYHEKPVLP 783 >6DG4-A nrPDB Length = 263 Score = 28.9 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 7/87 (8%) Query: 1 MAGAGPKRRALAAPAAEEKEEAREKMLAAKSAD-GSAPAGEGEGVTLQR---NITLLNGV 56 M+G P R L P + EE R ++ AA++A+ + A EG L R LL Sbjct: 1 MSGLRPPARQLITPLS---EEWRSRVEAARNANPATELAKTLEGQPLVRRDFEEKLLPAT 57 Query: 57 AIIVGTIIGSGIFVTPTGVLKEAGSPG 83 A + +I IF V + G+P Sbjct: 58 AWLNDNVIIGAIFYIADYVNTKKGAPN 84 >6HUO-B nrPDB Length = 473 Score = 28.5 bits (62), Expect = 6.6, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 29/85 (34%), Gaps = 10/85 (11%) Query: 119 YMLEVYGS-LPAFLKLWIELLIIRPSSQYIVALVFATYL--------LKPLFPTCP-VPE 168 ++L+ Y + + W+ I +S VAL T L L+ P P V Sbjct: 246 FILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKA 305 Query: 169 EAAKLVACLCVLLLTAVNCYSVKAA 193 L+ C + L + V Sbjct: 306 IDMYLMGCFVFVFLALLEYAFVNYI 330 >4COF-A nrPDB Length = 355 Score = 28.1 bits (61), Expect = 9.3, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 34/95 (35%), Gaps = 10/95 (10%) Query: 119 YMLEVYGS-LPAFLKLWIELLIIRPSSQYIVALVFATYL--------LKPLFPTCP-VPE 168 ++L+ Y + + W+ I +S VAL T L L+ P P V Sbjct: 224 FILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKA 283 Query: 169 EAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAA 203 L+ C + L + V Q A AAA Sbjct: 284 IDMYLMGCFVFVFLALLEYAFVNYIFFSQPARAAA 318 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.321 0.132 0.352 Lambda K H 0.267 0.0401 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,185,713 Number of Sequences: 36641 Number of extensions: 708050 Number of successful extensions: 2436 Number of sequences better than 10.0: 50 Number of HSP's better than 10.0 without gapping: 14 Number of HSP's successfully gapped in prelim test: 51 Number of HSP's that attempted gapping in prelim test: 2348 Number of HSP's gapped (non-prelim): 77 length of query: 507 length of database: 10,336,785 effective HSP length: 101 effective length of query: 406 effective length of database: 6,636,044 effective search space: 2694233864 effective search space used: 2694233864 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.4 bits) S2: 61 (28.1 bits)