BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q00796 (357 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1PL8-A nrPDB 728 0.0 3QE3-A nrPDB 651 0.0 1E3J-A nrPDB 418 e-117 3M6I-A nrPDB 281 2e-76 5VM2-A nrPDB 222 2e-58 2DQ4-A nrPDB 172 2e-43 6DKH-A nrPDB 168 3e-42 3GFB-A nrPDB 154 4e-38 5KIA-A nrPDB 146 1e-35 2DFV-A nrPDB 144 6e-35 4EJ6-A nrPDB 133 1e-31 4ILK-A nrPDB 131 6e-31 2EER-A nrPDB 122 2e-28 4UEJ-A nrPDB 118 3e-27 4CPD-A nrPDB 118 4e-27 3PII-A nrPDB 112 2e-25 4OH1-A nrPDB 111 5e-25 5K1S-A nrPDB 100 1e-21 3IP1-A nrPDB 98 5e-21 1LLU-A nrPDB 96 2e-20 1HSO-A nrPDB 96 2e-20 4EEZ-A nrPDB 95 4e-20 1R37-A nrPDB 94 1e-19 1HSZ-A nrPDB 92 4e-19 5YLN-A nrPDB 92 4e-19 1EE2-A nrPDB 92 5e-19 1U3W-A nrPDB 91 6e-19 3COS-A nrPDB 91 8e-19 1YKF-A nrPDB 90 1e-18 1H2B-A nrPDB 88 6e-18 3S2F-A nrPDB 87 1e-17 3FPC-A nrPDB 87 1e-17 1E3E-A nrPDB 87 1e-17 1D1T-A nrPDB 87 2e-17 4Z6K-A nrPDB 86 2e-17 4DLA-A nrPDB 85 4e-17 5ENV-A nrPDB 84 7e-17 3FSR-A nrPDB 84 1e-16 4RQU-A nrPDB 83 2e-16 1CDO-A nrPDB 81 9e-16 3MEQ-A nrPDB 80 1e-15 3FPL-A nrPDB 80 1e-15 2OUI-A nrPDB 79 3e-15 4JJI-A nrPDB 78 6e-15 6FG0-A nrPDB 78 6e-15 1F8F-A nrPDB 78 7e-15 4RVS-A nrPDB 77 8e-15 2DPH-A nrPDB 76 2e-14 2H6E-A nrPDB 75 3e-14 1KEV-A nrPDB 74 6e-14 6N7L-A nrPDB 74 8e-14 1P0F-A nrPDB 74 1e-13 4JLW-A nrPDB 73 2e-13 5TNX-A nrPDB 72 3e-13 1MC5-A nrPDB 71 7e-13 4GKV-A nrPDB 69 2e-12 3UOG-A nrPDB 69 4e-12 5YAT-A nrPDB 68 5e-12 3WLE-A nrPDB 64 9e-11 4A10-A nrPDB 62 4e-10 3FBG-A nrPDB 60 1e-09 3QWB-A nrPDB 60 2e-09 1KOL-A nrPDB 57 1e-08 1YB5-A nrPDB 55 6e-08 3JYN-A nrPDB 55 6e-08 1Q1N-A nrPDB 54 9e-08 4OAQ-A nrPDB 53 2e-07 3TWO-A nrPDB 52 4e-07 1QOR-A nrPDB 50 1e-06 4A27-A nrPDB 49 2e-06 4EYE-A nrPDB 49 3e-06 1YQX-A nrPDB 48 5e-06 3TQH-A nrPDB 48 7e-06 5H82-A nrPDB 46 2e-05 1WLY-A nrPDB 46 3e-05 1UUF-A nrPDB 45 3e-05 2VWH-A nrPDB 45 4e-05 5FI5-A nrPDB 45 4e-05 2VN8-A nrPDB 45 4e-05 2CDC-A nrPDB 44 9e-05 3HZZ-A nrPDB 44 1e-04 5H83-A nrPDB 43 2e-04 3B70-A nrPDB 42 3e-04 4J6F-A nrPDB 40 0.001 5Z0C-A nrPDB 40 0.001 5A3V-A nrPDB 40 0.002 4IDE-A nrPDB 39 0.003 5VKT-A nrPDB 39 0.003 2WEK-A nrPDB 36 0.027 2VCY-A nrPDB 34 0.076 6C49-A nrPDB 33 0.14 2OBY-A nrPDB 33 0.21 4DVJ-A nrPDB 32 0.33 2CF5-A nrPDB 32 0.52 2HPW-A nrPDB 31 0.67 4MAG-A nrPDB 31 0.87 1CS1-A nrPDB 30 1.1 3WID-A nrPDB 29 2.4 3MGG-A nrPDB 29 2.5 6DEO-A nrPDB 28 6.7 >1PL8-A nrPDB Length = 356 Score = 728 bits (1879), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/356 (99%), Positives = 355/356 (99%) Query: 2 AAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI 61 AAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI Sbjct: 1 AAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI 60 Query: 62 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA 121 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA Sbjct: 61 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA 120 Query: 122 TPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA 181 TPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA Sbjct: 121 TPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA 180 Query: 182 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLG 241 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLG Sbjct: 181 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLG 240 Query: 242 CKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYC 301 CKPEVTIECTGAEASIQAGIYATRSGG LVLVGLGSEMTTVPLLHAAIREVDIKGVFRYC Sbjct: 241 CKPEVTIECTGAEASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYC 300 Query: 302 NTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP 357 NTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP Sbjct: 301 NTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP 356 >3QE3-A nrPDB Length = 355 Score = 651 bits (1679), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/355 (87%), Positives = 335/355 (94%), Gaps = 2/355 (0%) Query: 5 AKP--NNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIV 62 AKP NLSLVVHGPGDLRLENYPIPEPGPNEVLL+MHSVGICGSDVHYW++GRIG+F+V Sbjct: 1 AKPAAENLSLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVV 60 Query: 63 KKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCAT 122 KKPMVLGHEASGTV KVGS V+HL+PGDRVAI+PGAPR+ DEFCK+GRYNLSP+IFFCAT Sbjct: 61 KKPMVLGHEASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCAT 120 Query: 123 PPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAG 182 PPDDGNLCRFYKHNA FCYKLPDNVTFEEGALIEPLSVGIHACRR GVTLG+KVLVCGAG Sbjct: 121 PPDDGNLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAG 180 Query: 183 PIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGC 242 PIG+V LL AKAMGAAQVVVTDLSA+RLSKAKE+GAD +L+IS ESP+EIA+KVEG LG Sbjct: 181 PIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVEGLLGS 240 Query: 243 KPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCN 302 KPEVTIECTG E SIQAGIYAT SGG LVLVGLGSEMT+VPL+HAA REVDIKGVFRYCN Sbjct: 241 KPEVTIECTGVETSIQAGIYATHSGGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRYCN 300 Query: 303 TWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP 357 TWP+AISMLASKSVNVKPLVTHRFPLEKALEAFET KKGLGLK+M+KCDPSDQNP Sbjct: 301 TWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGLKVMIKCDPSDQNP 355 >1E3J-A nrPDB Length = 352 Score = 418 bits (1074), Expect = e-117, Method: Compositional matrix adjust. Identities = 207/347 (59%), Positives = 255/347 (73%), Gaps = 5/347 (1%) Query: 8 NNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMV 67 +NLS V++ DLRLE PIPEP +EVLL+M VGICGSDVHY+E+GRI +FIVK PMV Sbjct: 4 DNLSAVLYKQNDLRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMV 63 Query: 68 LGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDG 127 +GHEASGTV KVG +VKHLK GDRVA+EPG P +FCK G+YNL P + FCATPPDDG Sbjct: 64 IGHEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTFCATPPDDG 123 Query: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMV 187 NL R+Y H A FC+KLPDNV+ EEGAL+EPLSVG+HACRR GV LG VLV GAGPIG+V Sbjct: 124 NLARYYVHAADFCHKLPDNVSLEEGALLEPLSVGVHACRRAGVQLGTTVLVIGAGPIGLV 183 Query: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQI--SKESPQEIARKVEGQLGCKPE 245 ++L AKA GA VV T S RL AK GAD+ L + +KE I ++ +G P Sbjct: 184 SVLAAKAYGAF-VVCTARSPRRLEVAKNCGADVTLVVDPAKEEESSIIERIRSAIGDLPN 242 Query: 246 VTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWP 305 VTI+C+G E I GI TR+GG L+LVG+GS+M TVPL++A RE+DIK VFRYCN +P Sbjct: 243 VTIDCSGNEKCITIGINITRTGGTLMLVGMGSQMVTVPLVNACAREIDIKSVFRYCNDYP 302 Query: 306 VAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLG--LKIMLKC 350 +A+ M+AS NVK LVTH F LE+ ++AFE +K +K+M+ C Sbjct: 303 IALEMVASGRCNVKQLVTHSFKLEQTVDAFEAARKKADNTIKVMISC 349 >3M6I-A nrPDB Length = 363 Score = 281 bits (720), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 157/347 (45%), Positives = 221/347 (63%), Gaps = 11/347 (3%) Query: 1 MAAAAKPNNLSLVVHGPGDLRL-ENYPIPEP-------GPNEVLLRMHSVGICGSDVHYW 52 MA++A N+ + + DL + E P E EV + + S GICGSDVH+W Sbjct: 1 MASSASKTNIGVFTNPQHDLWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFW 60 Query: 53 EYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYN 112 ++G IG IV+ VLGHE++G V V SVK +K GDRVAIEP E C GRYN Sbjct: 61 KHGCIGPMIVECDHVLGHESAGEVIAVHPSVKSIKVGDRVAIEPQVICNACEPCLTGRYN 120 Query: 113 LSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTL 172 + F +TPP G L R+ H A +C+K+ N+++E GA++EPLSV + +R GV L Sbjct: 121 GCERVDFLSTPPVPGLLRRYVNHPAVWCHKI-GNMSYENGAMLEPLSVALAGLQRAGVRL 179 Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL-QISKESPQE 231 G VL+CGAGPIG++T+L AKA GA +V+TD+ RL AKEI ++V ++ + S +E Sbjct: 180 GDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEICPEVVTHKVERLSAEE 239 Query: 232 IARK-VEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIR 290 A+K VE G +P V +ECTG E+SI A I+A + GG + ++G+G +P + A++R Sbjct: 240 SAKKIVESFGGIEPAVALECTGVESSIAAAIWAVKFGGKVFVIGVGKNEIQIPFMRASVR 299 Query: 291 EVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFET 337 EVD++ +RYCNTWP AI ++ + V++ LVTHRFPLE AL+AFET Sbjct: 300 EVDLQFQYRYCNTWPRAIRLVENGLVDLTRLVTHRFPLEDALKAFET 346 >5VM2-A nrPDB Length = 347 Score = 222 bits (566), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 128/333 (38%), Positives = 190/333 (57%), Gaps = 11/333 (3%) Query: 9 NLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKP--- 65 N ++ PG +++ + IP P +EVL+++ VGICGSDVH +E G FI K Sbjct: 3 NSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESG---PFIPPKDPNQ 59 Query: 66 -MVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP 124 + LGHE +GTV VGS V+ KPGDRV IEPG P + +C G+YN+ P + F AT P Sbjct: 60 EIGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQP 119 Query: 125 D-DGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGP 183 + G L + H +F YKLPDN+ EG L+EP +VG+HA V G K+++ GAG Sbjct: 120 NYRGALTHYLCHPESFTYKLPDNMDTMEGTLVEPAAVGMHAAMLADVKPGKKIIILGAGC 179 Query: 184 IGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCK 243 IG++TL K +GA ++ V D+ RL+ A+++GA +V+ +KE IAR + Sbjct: 180 IGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAKED--TIARCQQFTEDMG 237 Query: 244 PEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNT 303 ++ E G+ +++ Y GG +++VG + + L REV I+ VFRY N Sbjct: 238 ADIVFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGASAINFLKIN-REVTIQTVFRYANR 296 Query: 304 WPVAISMLASKSVNVKPLVTHRFPLEKALEAFE 336 +PV I ++S +VK +VTH + +AFE Sbjct: 297 YPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >2DQ4-A nrPDB Length = 343 Score = 172 bits (436), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 108/340 (31%), Positives = 175/340 (51%), Gaps = 18/340 (5%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 L L + P+PEPGP E+L+R+ + ICG+D+H W++ ++ P+V GHE SG VE V Sbjct: 13 LTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPLVTGHEFSGVVEAV 72 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAF 139 G V+ + GD V++E C+ G Y++ + DG + A Sbjct: 73 GPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQILGV-DRDGGFAEYVVVPAEN 131 Query: 140 CYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQ 199 + P ++ FE A++EP +H G G VL+ GAGPIG++ +V +A GA Sbjct: 132 AWVNPKDLPFEVAAILEPFGNAVHTVYAGSGVSGKSVLITGAGPIGLMAAMVVRASGAGP 191 Query: 200 VVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQA 259 ++V+D + RL+ A+ AD ++ +E E+ R+V G EV +E +G EA+I Sbjct: 192 ILVSDPNPYRLAFARPY-ADRLVNPLEEDLLEVVRRVTGS---GVEVLLEFSGNEAAIHQ 247 Query: 260 GIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVF-------RYCNTWPVAISMLA 312 G+ A GG ++G+ S+ P+ E+ ++G+ R TW +++ Sbjct: 248 GLMALIPGGEARILGIPSD----PIRFDLAGELVMRGITAFGIAGRRLWQTWMQGTALVY 303 Query: 313 SKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDP 352 S V++ PL+THR PL + EAF G +K++L DP Sbjct: 304 SGRVDLSPLLTHRLPLSRYREAFGLLASGQAVKVIL--DP 341 >6DKH-A nrPDB Length = 346 Score = 168 bits (426), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 99/307 (32%), Positives = 160/307 (52%), Gaps = 11/307 (3%) Query: 33 NEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRV 92 N L+++ GICGSD+HY++ G++GNF++K PMVLGHE G V + S L G V Sbjct: 31 NGTLVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTV 88 Query: 93 AIEPGAPRENDEFCKMGRYNLSPSIFFCAT----PPDDGNLCRFYKHNAAFCYKLPDNVT 148 AI P P + ++C N + F + P DG R+ + C P Sbjct: 89 AINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKAD 148 Query: 149 FEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSAT 208 + A EPL+V IHA + G G +V + G GPIG + + K +GAA++V D+S Sbjct: 149 EKVMAFAEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPR 208 Query: 209 RLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGG 268 LS KE+GAD+++ + + + +G +V+ E +G +S+ + TR+ G Sbjct: 209 SLSLGKEMGADVLVN-PQNDDMDHWKAEKGYF----DVSFEVSGHPSSVNTCLEVTRARG 263 Query: 269 NLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPL 328 +V VG+G M P++ +E+ ++G FR+ + + A+S LA+ +N PL++ +P Sbjct: 264 VMVQVGMGGAMAEFPMMTLIGKEISLRGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPF 323 Query: 329 EKALEAF 335 EA Sbjct: 324 TDLEEAL 330 >3GFB-A nrPDB Length = 350 Score = 154 bits (390), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 101/328 (30%), Positives = 171/328 (52%), Gaps = 12/328 (3%) Query: 27 IPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHL 86 +P+PGP EVL+++ + ICG+D+H +E+ +K P ++GHE +G V +VG V+ L Sbjct: 24 VPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEVGPGVEDL 83 Query: 87 KPGDRVAIEPGAPRENDEFCKMGRYNL--SPSIFFCATPPDDGNLCRFYKHNAAFCYKLP 144 + GD +++E CK RY++ + IF DG + A +K P Sbjct: 84 QVGDYISVETHIVCGKCYACKHNRYHVCQNTKIFGVDM---DGVFAHYAIVPAKNAWKNP 140 Query: 145 DNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTD 204 ++ E AL EPL + G + G L+ GAGP+G++ + VAKA GA V+V++ Sbjct: 141 KDMPPEYAALQEPLGNAVDTVLAGPIA-GRSTLITGAGPLGLLGIAVAKASGAYPVIVSE 199 Query: 205 LSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYAT 264 S R AK++GAD V+ +E P + + G EV +E +GA +++ G+ A Sbjct: 200 PSEFRRKLAKKVGADYVVNPFEEDPVKFVMDITDGAGV--EVFLEFSGAPKALEQGLKAV 257 Query: 265 RSGGNLVLVGLGSEMTTVPLLHAAI-REVDIKGVF--RYCNTWPVAISMLASKSVNVKPL 321 GG + L+GL T+ + I + +++ G+ TW S++ S +N+ P+ Sbjct: 258 TPGGRVSLLGLFPREVTIDFNNLIIFKALEVHGITGRHLWETWYTVSSLIQSGKLNLDPI 317 Query: 322 VTHRFP-LEKALEAFETFKKGLGLKIML 348 +TH++ +K EAFE + G K++ Sbjct: 318 ITHKYKGFDKFEEAFELMRAGKTGKVVF 345 >5KIA-A nrPDB Length = 351 Score = 146 bits (369), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 93/341 (27%), Positives = 171/341 (50%), Gaps = 8/341 (2%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 L+ + GPG L L PE G N+VL+++ ICG+D+H W++ + PM +G Sbjct: 12 LAKLERGPG-LTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVG 70 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNL 129 HE G + ++G V+ GDRV+ E C+ GR +L + +G Sbjct: 71 HEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNR-EGAF 129 Query: 130 CRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTL 189 + A +K+P ++ + A+ +P H + +G VL+ GAGPIG++ + Sbjct: 130 AEYLAIPAFNAFKIPPEISDDLAAIFDPFGNATHTALSFNL-VGEDVLITGAGPIGVMAV 188 Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249 +AK +GA VV+TD++ RL A+ +GA + +S+ES +++ + G +V +E Sbjct: 189 AIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRESLRDVMADLHMTEGF--DVGLE 246 Query: 250 CTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVF--RYCNTWPVA 307 +G ++ + + + GG + L+G+ T + + ++IKG++ TW Sbjct: 247 MSGVPSAFTSLLESMNHGGKVALLGIPPAQTAIDWNQVIFKGLEIKGIYGREMFETWYKM 306 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 ++ML S +++ P++THRF ++ + F G K++L Sbjct: 307 VAMLQS-GLDLSPIITHRFAVDDYEKGFAAMLSGESGKVIL 346 >2DFV-A nrPDB Length = 347 Score = 144 bits (363), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 98/329 (29%), Positives = 172/329 (52%), Gaps = 14/329 (4%) Query: 27 IPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHL 86 +P+PGP EVL+++ + ICG+D+H +E+ +K P ++GHE +G V ++G V+ + Sbjct: 23 VPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIGPGVEGI 82 Query: 87 KPGDRVAIEPGAPRENDEFCKMGRYNL--SPSIFFCATPPDDGNLCRFYKHNAAFCYKLP 144 + GD V++E C+ G+Y++ + IF T DG + A +K P Sbjct: 83 EVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGVDT---DGVFAEYAVVPAQNIWKNP 139 Query: 145 DNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTD 204 ++ E L EPL + G ++ G VL+ GAGP+G++ + VAKA GA V+V++ Sbjct: 140 KSIPPEYATLQEPLGNAVDTVLAGPIS-GKSVLITGAGPLGLLGIAVAKASGAYPVIVSE 198 Query: 205 LSATRLSKAKEIGADLVLQ-ISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYA 263 S R AK++GAD V+ ++ +E+ +G +V +E +GA +++ G+ A Sbjct: 199 PSDFRRELAKKVGADYVINPFEEDVVKEVMDITDGN---GVDVFLEFSGAPKALEQGLQA 255 Query: 264 TRSGGNLVLVGLGSEMTTVPLLHAAI-REVDIKGVF--RYCNTWPVAISMLASKSVNVKP 320 G + L+GL T+ + I + + I G+ TW +L S +N+ P Sbjct: 256 VTPAGRVSLLGLYPGKVTIDFNNLIIFKALTIYGITGRHLWETWYTVSRLLQSGKLNLDP 315 Query: 321 LVTHRFP-LEKALEAFETFKKGLGLKIML 348 ++TH++ +K EAFE + G K++ Sbjct: 316 IITHKYKGFDKYEEAFELMRAGKTGKVVF 344 >4EJ6-A nrPDB Length = 370 Score = 133 bits (335), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 86/319 (26%), Positives = 156/319 (48%), Gaps = 13/319 (4%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVE 77 G++ + N IPEPGP+++L+++ + GICG+D H G F P+ LGHE G V Sbjct: 33 GNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLH----GEFPSTPPVTLGHEFCGIVV 88 Query: 78 KVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNA 137 + GS+V+ + PG R+ +P C+ GR NL ++ DG + Sbjct: 89 EAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLRAIGIH-RDGGFAEYVLVPR 147 Query: 138 AFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGA 197 +++P + GA EPL+ +H G+ G V + G G IG++T+ +A+ GA Sbjct: 148 KQAFEIPLTLDPVHGAFCEPLACCLHGVDLSGIKAGSTVAILGGGVIGLLTVQLARLAGA 207 Query: 198 AQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP---EVTIECTGAE 254 V+++ AT+ A+E+GA + S ++ + G +G P +V IEC G Sbjct: 208 TTVILSTRQATKRRLAEEVGATATVD---PSAGDVVEAIAGPVGLVPGGVDVVIECAGVA 264 Query: 255 ASIQAGIYATRSGGNLVLVGL--GSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLA 312 +++ ++GG +V++G+ E + RE+ + G F A ++A Sbjct: 265 ETVKQSTRLAKAGGTVVILGVLPQGEKVEIEPFDILFRELRVLGSFINPFVHRRAADLVA 324 Query: 313 SKSVNVKPLVTHRFPLEKA 331 + ++ + +++ R L++A Sbjct: 325 TGAIEIDRMISRRISLDEA 343 >4ILK-A nrPDB Length = 359 Score = 131 bits (329), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 96/332 (28%), Positives = 154/332 (46%), Gaps = 13/332 (3%) Query: 11 SLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGH 70 S+++ P L + IP P EV +++ GICGSD H + R N K P V+GH Sbjct: 23 SILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIY---RGHNPFAKYPRVIGH 79 Query: 71 EASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLC 130 E G ++ VG V+ + G+RVA++P + C +G+ N+ ++ D G Sbjct: 80 EFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGVHAD-GGFS 138 Query: 131 RFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLL 190 + A +K+P+ V + +IEP ++ + G T VLV GAGPIG+ + Sbjct: 139 EYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTENDTVLVYGAGPIGLTIVQ 198 Query: 191 VAKAM-GAAQVVVTDLSATRLSKAKEIGADLVLQISKESP--QEIARKVEGQLGCKPEVT 247 V K + V+V D RL KAKE GAD + S ++P + A K G KP + Sbjct: 199 VLKGVYNVKNVIVADRIDERLEKAKESGADWAINNS-QTPLGESFAEK-----GIKPTLI 252 Query: 248 IECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVA 307 I+ + ++ + +VL+G SE + V +E+ I N +PV Sbjct: 253 IDAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKELSIFSSRLNANKFPVV 312 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFK 339 I L+ + + L+TH F + +A F+ Sbjct: 313 IDWLSKGLIKPEKLITHTFDFQHVADAISLFE 344 >2EER-A nrPDB Length = 347 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 101/341 (29%), Positives = 162/341 (47%), Gaps = 19/341 (5%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI------VKKPMVLGHEAS 73 L+LE+ PIP+P ++VL+++ + G+C SDVH + GR GN VK P+ LGHE + Sbjct: 13 LKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQ-GRFGNLRIVEDLGVKLPVTLGHEIA 71 Query: 74 GTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFY 133 G +E+VG V GD VA+ P N +C++G +L S + D Sbjct: 72 GRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLCDSPRWLGINYDGAYAEYVL 131 Query: 134 KHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA-GPIGMVTLLVA 192 + + YKL E L A R+ + ++V GA G +G + + +A Sbjct: 132 VPHYKYLYKLRRLSAVEAAPLTCSGVTTYRAVRKASLDPSKTLVVIGAGGGLGTMAIQIA 191 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESP-QEIARKVEGQLGCKPEVTIECT 251 KA+ A ++ D+ L AK GAD V+ S + P EI R +G+ + I+ Sbjct: 192 KAVSGATIIGVDVREEALEAAKRAGADYVINASSQDPVSEIRRITQGK---GADAVIDLN 248 Query: 252 GAEASIQAGIYATRSGGNLVLVGL-GSEMTT-VPLLHAAIREVDIKGVFRYCNTWPVAIS 309 +E ++ Y G V+VGL G+++ PL+ + EV G + + I Sbjct: 249 NSEKTLSIYPYVLAKQGKYVMVGLFGADLKYHAPLI--TLNEVQFIGSLVGNQSDFLGIM 306 Query: 310 MLASKSVNVKPLVTHRFPLEKALEAFETFK--KGLGLKIML 348 LA VKP+VT LE+A EA + + K +G ++++ Sbjct: 307 SLAEAG-KVKPMVTKTMKLEEANEAIDNLENFKAVGRQVLV 346 >4UEJ-A nrPDB Length = 346 Score = 118 bits (296), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 96/351 (27%), Positives = 157/351 (44%), Gaps = 39/351 (11%) Query: 11 SLVVHGPGDLRLENYPIPE-PGPNEVLLRMHSVGICGSDV--------HYWEYGRIGNFI 61 S+V G +R+ IPE +EV +++ S G+CGSD+ HY+ Sbjct: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY--------- 53 Query: 62 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA 121 P+ LGHE SG ++ VGS V L PGD VA P P C G Y+ F Sbjct: 54 ---PITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIG 110 Query: 122 TPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA 181 + DG + + LP ++ E+GA IEP++VG+HA V++ GA Sbjct: 111 SR-RDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGA 169 Query: 182 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESP---QEIARKVEG 238 G IG++ + A A+GA V D+S+ +L+ AK GA S+ S Q + R++ Sbjct: 170 GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF 229 Query: 239 QLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSE---MTTVPLLHAAIREVDIK 295 ++ +E G +++ + L LVG + +T+ +E+ + Sbjct: 230 N-----QLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVI 284 Query: 296 GVF-RYCNTWP-----VAISMLASKSVNVKPLVTHRFPLEKALEAFETFKK 340 G + Y + WP A +L + ++++PL+ HR E +A + Sbjct: 285 GSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIAR 335 >4CPD-A nrPDB Length = 347 Score = 118 bits (295), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 94/327 (28%), Positives = 154/327 (47%), Gaps = 18/327 (5%) Query: 32 PNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDR 91 P + L+R+H GICGSD+H + G V VLGHE G VE VG ++ L+PGD Sbjct: 25 PLDALVRVHLAGICGSDLHLYH----GKIPVLPGSVLGHEFVGQVEAVGEGIQDLQPGDW 80 Query: 92 VAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNL-------CRFYKHNAAFCYKLP 144 V +C+ +YNL P GNL R N KLP Sbjct: 81 VVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPMFGNLQGAQAEILRVPFSNVNL-RKLP 139 Query: 145 DNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVT 203 N++ E + LS +G + G V V GAGP+G++ + VA+ +GA++++ Sbjct: 140 PNLSPERAIFAGDILSTAYGGLIQGQLRPGDSVAVIGAGPVGLMAIEVAQVLGASKILAI 199 Query: 204 DLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYA 263 D RL +A +GA + + +E+P R G P++ +E G A++ + Sbjct: 200 DRIPERLERAASLGA-IPINAEQENPVRRVRSETNDEG--PDLVLEAVGGAATLSLALEM 256 Query: 264 TRSGGNLVLVGLGSEMT-TVPLLHAAIREVDIK-GVFRYCNTWPVAISMLASKSVNVKPL 321 R GG + VG+ + + PL ++++ + G+ +++LAS + + + Sbjct: 257 VRPGGRVSAVGVDNAPSFPFPLASGLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERI 316 Query: 322 VTHRFPLEKALEAFETFKKGLGLKIML 348 V+H PLE+A +E F + LK++L Sbjct: 317 VSHYLPLEEAPRGYELFDRKEALKVLL 343 >3PII-A nrPDB Length = 339 Score = 112 bits (281), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 102/331 (30%), Positives = 149/331 (45%), Gaps = 26/331 (7%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMVLGHEASGTVE 77 L+++ P EVL+R+ + G+C +D+H G++ VK P++ GHE G VE Sbjct: 13 LKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAH----GDWPVKPKLPLIPGHEGVGIVE 68 Query: 78 KVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD-----DGNLCRF 132 +VG V HLK GDRV I P C Y LS C + DG + Sbjct: 69 EVGPGVTHLKVGDRVGI----PWLYSA-CGHCDYCLSGQETLCEHQKNAGYSVDGGYAEY 123 Query: 133 YKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGMVTLLV 191 + A + K+PDN++FEE A I V + A + G G V + G G G V + Sbjct: 124 CRAAADYVVKIPDNLSFEEAAPIFCAGVTTYKALKVTGAKPGEWVAIYGIGGFGHVAVQY 183 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECT 251 AKAMG VV D+ +L AKE+GADLV+ KE + ++ G + + Sbjct: 184 AKAMG-LNVVAVDIGDEKLELAKELGADLVVNPLKEDAAKFMKEKVGGV----HAAVVTA 238 Query: 252 GAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKG-VFRYCNTWPVAISM 310 ++ + Q+ + R GG VLVGL E +P+ + + I G + A+ Sbjct: 239 VSKPAFQSAYNSIRRGGACVLVGLPPEEMPIPIFDTVLNGIKIIGSIVGTRKDLQEALQF 298 Query: 311 LASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 A V + PLEK E F+ KG Sbjct: 299 AAEGKVKT---IIEVQPLEKINEVFDRMLKG 326 >4OH1-A nrPDB Length = 351 Score = 111 bits (277), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 87/343 (25%), Positives = 162/343 (47%), Gaps = 20/343 (5%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK----PMVLGHEAS 73 G + + P+PEP E+ +++ ICGSD H G +G PM GHE S Sbjct: 19 GTVDMMEAPMPEPKDEEIRIKVVYASICGSDTHILT-GNLGEMESTTRSMLPMSFGHELS 77 Query: 74 GTVEKVGSSVKHL--KPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCR 131 G ++KVGS+ + + K G +V E C+ G+ NL ++ + Sbjct: 78 GVIDKVGSTAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSNMGYRMN-----GFSE 132 Query: 132 FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLV 191 + ++ + + +PD+ ++ AL+EPL+V + + + ++ G V + GAG +GM+ + + Sbjct: 133 YAVYHMSQIFPIPDDADLKDYALVEPLTVALSSAEQAKISYGKSVAIMGAGGLGMMLVQL 192 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECT 251 A+ GA+ + V D+ +L A E GAD L ++E E A ++ G + + +E T Sbjct: 193 ARLAGASTITVFDIVPEKLELALENGADYALNSAEEGVAERAIELAGG---RYDCVLEGT 249 Query: 252 GAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL-LHAAI--REVDIKGVFRYCNTWPVAI 308 GA A+ + G+ G+ V + + +P+ L + + + I G+ + +P +I Sbjct: 250 GATAAAKLGLQLLARDGDAVYFAMYGKDPILPVNLQSDLYWDQKHIHGMIQGAWQFPKSI 309 Query: 309 SMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCD 351 M+ ++ ++ L +AFE KI++K D Sbjct: 310 RMIP--RMDFSKIIQKEHTLTNYKQAFEDLYSKKYAKIVIKMD 350 >5K1S-A nrPDB Length = 362 Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 95/326 (29%), Positives = 159/326 (48%), Gaps = 22/326 (6%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF-IVKKPMVLGHEASGTV 76 G+L++E P+P PG EVLLR+H+ G+C DV R GN P +LGHEA+G V Sbjct: 30 GNLKMETMPMPRPGRGEVLLRVHACGVCYHDV----INRRGNLPRTSVPAILGHEAAGEV 85 Query: 77 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNL--SPSIFFCATPPDDGNLCRFYK 134 +VG K GDR A + C+ GR +L + + FF P G +F Sbjct: 86 IEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTDNRFFGEELP--GGYAQFMV 143 Query: 135 HNAAFCYKLPDNVTFEEGALI-EPLSVGIHACR-RGGVTLGHKVLVCGA-GPIGMVTLLV 191 ++P ++ + E A + +H R RG V G VL+ GA G +G+ ++ + Sbjct: 144 APVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTRGKVRAGETVLITGASGGVGLSSVQL 203 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK--ESPQEIARKVEGQLGCKPEVTIE 249 A+ GA + VT S ++ KE GAD V+ +S+ + ++ ++ + G +V +E Sbjct: 204 ARLDGARVIAVTS-SEAKVQALKEAGADEVI-VSRGLDFASDVRKRTQ---GAGVDVAVE 258 Query: 250 CTGAEASIQAGIYATRSGGNLVLVG-LGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAI 308 G+ A+ + + GG +V+VG L S M + ++E++I G + + Sbjct: 259 IVGS-ATFDQTLKSMAPGGRVVVVGNLESGMVQLNPGLVIVKELEILGAYATTQA-ELDE 316 Query: 309 SMLASKSVNVKPLVTHRFPLEKALEA 334 ++ + + V+ VT PL +A +A Sbjct: 317 ALRLTATGGVRQFVTDAVPLAEAAKA 342 >3IP1-A nrPDB Length = 404 Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 95/350 (27%), Positives = 160/350 (45%), Gaps = 35/350 (10%) Query: 19 DLRLENYPIPE-PGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK----PMVLGHEAS 73 ++R+E P P P E+++++ + GICGSDVH + G + P+ LGHE S Sbjct: 41 EVRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGHEFS 100 Query: 74 GTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPD-----D 126 G V + G + + R I G P +E G F C + D Sbjct: 101 GVVVEAGPEAINRRTNKRFEI--GEPVCAEEMLWCGHCRPCAEGFPNHCENLNELGFNVD 158 Query: 127 GNLCRFYKHNAAFCYKLPD-------NVTFEEGALIEPLSVGIHAC--RRGGVTLGHKVL 177 G + K +A + + L + + F G+L+EP SV +A R GG+ G V+ Sbjct: 159 GAFAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLVEPTSVAYNAVIVRGGGIRPGDNVV 218 Query: 178 VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVE 237 + G GPIG+ + + K GA++V++++ S R + AKE+GAD V+ +KE+ E Sbjct: 219 ILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDPTKENFVEAVLDYT 278 Query: 238 GQLGCKPEVTIECTGAEA----SIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAA--IRE 291 LG K + +E TG I+ I+ R G N + + +PL +R Sbjct: 279 NGLGAK--LFLEATGVPQLVWPQIEEVIWRAR-GINATVAIVARADAKIPLTGEVFQVRR 335 Query: 292 VDIKGVFRYC--NTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFK 339 I G + T+P IS++AS +++ +++ +E+ E + + Sbjct: 336 AQIVGSQGHSGHGTFPRVISLMAS-GMDMTKIISKTVSMEEIPEYIKRLQ 384 >1LLU-A nrPDB Length = 342 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 90/294 (30%), Positives = 135/294 (45%), Gaps = 25/294 (8%) Query: 13 VVHGPGD-LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPM--VLG 69 VVH G LR+E +P PGP +VL+++ + G+C +D+H E G++ VK P+ + G Sbjct: 11 VVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAE----GDWPVKPPLPFIPG 66 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD---- 125 HE G V VGS V +K GDRV I P C + L+ C + + Sbjct: 67 HEGVGYVAAVGSGVTRVKEGDRVGI----PWLYTA-CGCCEHCLTGWETLCESQQNTGYS 121 Query: 126 -DGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGP 183 +G + + + LP NV F E A I V ++ ++ G V + G G Sbjct: 122 VNGGYAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVYKGLKQTNARPGQWVAISGIGG 181 Query: 184 IGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQE-IARKVEGQLGC 242 +G V + A+AMG V D+ +L A+++GA L + +E P E I R + G G Sbjct: 182 LGHVAVQYARAMGL-HVAAIDIDDAKLELARKLGASLTVNARQEDPVEAIQRDIGGAHG- 239 Query: 243 KPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKG 296 V + A QA I R GG + LVGL P+ ++ + I G Sbjct: 240 ---VLVTAVSNSAFGQA-IGMARRGGTIALVGLPPGDFPTPIFDVVLKGLHIAG 289 >1HSO-A nrPDB Length = 374 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 97/364 (26%), Positives = 156/364 (42%), Gaps = 47/364 (12%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 +E + P +EV ++M +VGICG+D H G + P++LGHEA+G VE V Sbjct: 21 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILGHEAAGIVESV 76 Query: 80 GSSVKHLKPGDRV---AI------------EPGAPRENDEFCKMGRYNLSPSIFFCATPP 124 G V +KPGD+V AI E +ND G S F C P Sbjct: 77 GEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKP 136 Query: 125 DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTLG 173 + F + Y + D + PL S G A VT G Sbjct: 137 ----IHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG 192 Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQE 231 V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Q K+ QE Sbjct: 193 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 252 Query: 232 IARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSE-----MTTVPL 284 + +++ +G + + + E G ++ A + G V+VG+ + M + L Sbjct: 253 VLKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL 308 Query: 285 LHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL 344 L + I G F+ P ++ +K ++ L+TH P EK E F+ G + Sbjct: 309 LTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSI 368 Query: 345 KIML 348 + +L Sbjct: 369 RTIL 372 >4EEZ-A nrPDB Length = 348 Score = 95.1 bits (235), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 86/316 (27%), Positives = 145/316 (45%), Gaps = 19/316 (6%) Query: 32 PNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDR 91 PNE LL M G+C +D+H G+F K VLGHE G V+++G+ V L+ GDR Sbjct: 26 PNEALLDMEYCGVCHTDLHV----AAGDFGNKAGTVLGHEGIGIVKEIGADVSSLQVGDR 81 Query: 92 VAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD-----DGNLCRFYKHNAAFCYKLPDN 146 V++ E C Y +S + FC + DG + A + K+PD Sbjct: 82 VSVAWFF-----EGCGHCEYCVSGNETFCREVKNAGYSVDGGMAEEAIVVADYAVKVPDG 136 Query: 147 VTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDL 205 + E + I V + A + GV G ++ GAG +G + + AK + A+V+ D+ Sbjct: 137 LDPIEASSITCAGVTTYKAIKVSGVKPGDWQVIFGAGGLGNLAIQYAKNVFGAKVIAVDI 196 Query: 206 SATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATR 265 + +L+ AK+IGAD+ + +P + +K+ G LG + I C A + + + + + Sbjct: 197 NQDKLNLAKKIGADVTINSGDVNPVDEIKKITGGLGVQS--AIVCAVARIAFEQAVASLK 254 Query: 266 SGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHR 325 G +V V + + T+ + V++ G +A + VKP+V R Sbjct: 255 PMGKMVAVAVPNTEMTLSVPTVVFDGVEVAGSL-VGTRLDLAEAFQFGAEGKVKPIVATR 313 Query: 326 FPLEKALEAFETFKKG 341 LE+ + + K G Sbjct: 314 -KLEEINDIIDEMKAG 328 >1R37-A nrPDB Length = 347 Score = 93.6 bits (231), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 91/340 (26%), Positives = 154/340 (45%), Gaps = 17/340 (5%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI------VKKPMVLGHEAS 73 L L+ +P+P +VL+++ + G+C SDVH + GR GN VK P+ LGHE + Sbjct: 13 LSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQ-GRFGNLRIVEDLGVKLPVTLGHEIA 71 Query: 74 GTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFY 133 G +E+VG V GD VA+ P N +C++G +L S + D Sbjct: 72 GKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLCDSPRWLGINFDGAYAEYVI 131 Query: 134 KHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVT-LGHKVLVCGAGPIGMVTLLVA 192 + + YKL E L A R+ + ++V G +G + + +A Sbjct: 132 VPHYKYMYKLRRLNAVEAAPLTCSGITTYRAVRKASLDPTKTLLVVGAGGGLGTMAVQIA 191 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTG 252 KA+ A ++ D+ + AK GAD V+ S + P R++ G + I+ Sbjct: 192 KAVSGATIIGVDVREEAVEAAKRAGADYVINASMQDPLAEIRRITESKGV--DAVIDLNN 249 Query: 253 AEASIQAGIYATRSGGNLVLVGL-GSEM-TTVPLLHAAIREVDIKGVFRYCNTWPVAISM 310 +E ++ A G V+VGL G+++ PL+ + E+ G + + I Sbjct: 250 SEKTLSVYPKALAKQGKYVMVGLFGADLHYHAPLI--TLSEIQFVGSLVGNQSDFLGIMR 307 Query: 311 LASKSVNVKPLVTHRFPLEKALEAFETFK--KGLGLKIML 348 LA VKP++T LE+A EA + + K +G ++++ Sbjct: 308 LAEAG-KVKPMITKTMKLEEANEAIDNLENFKAIGRQVLI 346 >1HSZ-A nrPDB Length = 374 Score = 91.7 bits (226), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 97/367 (26%), Positives = 158/367 (43%), Gaps = 53/367 (14%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 +E+ + P EV ++M +VGIC +D H GN + P++LGHEA+G VE V Sbjct: 21 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVS----GNLVTPLPVILGHEAAGIVESV 76 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGN----------- 128 G V +KPGD+V I P+ C R +P +C D GN Sbjct: 77 GEGVTTVKPGDKV-IPLFTPQ-----CGKCRVCKNPESNYC-LKNDLGNPRGTLQDGTRR 129 Query: 129 -LCR------FYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGV 170 CR F + Y + D + PL S G A V Sbjct: 130 FTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKV 189 Query: 171 TLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKES 228 T G V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Q K+ Sbjct: 190 TPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 249 Query: 229 PQEIARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL---GSEMTTVP 283 QE+ +++ +G + + + E G ++ A + G V+VG+ ++ P Sbjct: 250 IQEVLKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 305 Query: 284 LLHAAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 +L R + G F+ P ++ +K ++ L+TH P EK E F+ G Sbjct: 306 MLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 365 Query: 342 LGLKIML 348 ++ +L Sbjct: 366 KSIRTVL 372 >5YLN-A nrPDB Length = 356 Score = 91.7 bits (226), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 85/338 (25%), Positives = 150/338 (44%), Gaps = 26/338 (7%) Query: 32 PNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDR 91 P + ++R+ ICG+D+H + G + + +LGHE G VE+VG V + K GD+ Sbjct: 29 PTDAIVRIVKTTICGTDLHIIK-GDVPT--CQSGTILGHEGIGIVEEVGEGVSNFKKGDK 85 Query: 92 VAIEPGAPRENDEFCKMGRY----NLSPSIFFCATPPDDGNLCRFYK--HNAAFCYKLPD 145 V I +CK G Y + IF DG + + H Y P+ Sbjct: 86 VLISCVCACGKCYYCKKGIYAHCEDEGGWIFGHLI---DGMQAEYLRVPHADNTLYHTPE 142 Query: 146 NVTFEEGALIEPL-----SVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQV 200 +++ E ++ + +G+ +G V G V + G+GP+G+ LL A+ A++ Sbjct: 143 DLSDEALVMLSDILPTGYEIGV---LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKL 199 Query: 201 VVTDLSATRLSKAKEIGADLVLQISKESPQEIARKV-EGQLGCKPEVTIECTGAEASIQA 259 ++ DL RL A GA +++ P++ +++ + G +V IE G A+ Sbjct: 200 IMVDLDDNRLETALSFGA--THKVNSSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDF 257 Query: 260 GIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVK 319 G + G+ + L IR +++ NT P + L S + + Sbjct: 258 CQKIIGVDGTVANCGVHGKPVEFDLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPE 317 Query: 320 PLVTHRFPLEKALEAFETFKKGL---GLKIMLKCDPSD 354 LVTH F L + +A+E F K +K++++ D S+ Sbjct: 318 KLVTHYFKLSEIEKAYEVFSKAADHHAIKVIIENDISE 355 >1EE2-A nrPDB Length = 373 Score = 91.7 bits (226), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 93/363 (25%), Positives = 156/363 (42%), Gaps = 46/363 (12%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 +E + P +EV ++M + GIC SD H G + P++ GHEA+G VE + Sbjct: 21 FSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVS----GTLVAPLPVIAGHEAAGIVESI 76 Query: 80 GSSVKHLKPGDRVAIEPGAPREND-EFCKMGRYNL--------------SPSIFFCATPP 124 G V ++PGD+V I P+ CK NL S F C P Sbjct: 77 GEGVTTVRPGDKV-IPLFIPQCGKCSVCKHPEGNLCLKNLSMPRGTMQDGTSRFTCRGKP 135 Query: 125 DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTLG 173 + F + Y + D ++ + PL S G A + VT G Sbjct: 136 ----IHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGYGSAVKVAKVTQG 191 Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQE 231 V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Q K+ QE Sbjct: 192 STCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQE 251 Query: 232 IARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSE-----MTTVPLL 285 + ++ + + E G ++ A + + G V+VG+ + M + LL Sbjct: 252 VLTEMSNG---GVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLL 308 Query: 286 HAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLK 345 + I G F+ ++ P ++ +K + PL+TH P EK E F+ + G ++ Sbjct: 309 SGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGKSIR 368 Query: 346 IML 348 +L Sbjct: 369 TIL 371 >1U3W-A nrPDB Length = 374 Score = 91.3 bits (225), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 94/364 (25%), Positives = 158/364 (43%), Gaps = 47/364 (12%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 +E + P +EV ++M + GIC SD H GN + P++LGHEA+G VE V Sbjct: 21 FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS----GNLVTPLPVILGHEAAGIVESV 76 Query: 80 GSSVKHLKPGDRV----AIEPGAPR-----------ENDEFCKMGRYNLSPSIFFCATPP 124 G V +KPGD+V + G R +ND G F C+ P Sbjct: 77 GEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP 136 Query: 125 DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTLG 173 + F + Y + D + PL S G A + VT G Sbjct: 137 ----IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG 192 Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQE 231 V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Q K+ QE Sbjct: 193 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 252 Query: 232 IARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL---GSEMTTVPLLH 286 + +++ +G + + + E G ++ A + G V+VG+ ++ P+L Sbjct: 253 VLKEMTDGGV----DFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL 308 Query: 287 AAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL 344 R I G F+ + P ++ +K ++ L+T+ P EK E F+ + G + Sbjct: 309 LTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFDLLRSGKSI 368 Query: 345 KIML 348 + +L Sbjct: 369 RTVL 372 >3COS-A nrPDB Length = 381 Score = 90.9 bits (224), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 92/370 (24%), Positives = 165/370 (44%), Gaps = 54/370 (14%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 L +E + P +EV +++ + +C +D + G + P+++GHEA+G VE + Sbjct: 23 LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIVESI 79 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA------TPPDDGNL---- 129 G V ++KPGD+V I AP C+ ++ LSP C +P D L Sbjct: 80 GPGVTNVKPGDKV-IPLYAP-----LCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDK 133 Query: 130 -----CR------FYKHNAAFCY---------KLPDNVTFEEGALIE-PLSVGIHAC-RR 167 C+ F+ + Y K+ D+ E L+ S G A Sbjct: 134 TSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINN 193 Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQ---I 224 VT G V G G +G+ ++ KA GA++++ D+++ + KAK +GA L + Sbjct: 194 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDL 253 Query: 225 SKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL--GSEMTT 281 K + I +G + + ++C G +++A + T +G G+ +G+ GS+ T Sbjct: 254 HKPIQEVIIELTKGGV----DFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 309 Query: 282 V---PLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETF 338 V L+ G ++ ++ P ++ +K N+ LVTH P +K EAF+ Sbjct: 310 VFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 369 Query: 339 KKGLGLKIML 348 +G ++ +L Sbjct: 370 NQGKSIRTIL 379 >1YKF-A nrPDB Length = 352 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 94/341 (27%), Positives = 143/341 (41%), Gaps = 31/341 (9%) Query: 28 PEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLK 87 P PGP + ++R +V C SD+H G IG + M+LGHEA G V +VGS VK K Sbjct: 20 PAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGE---RHNMILGHEAVGEVVEVGSEVKDFK 76 Query: 88 PGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDGNLCRFYKHNAA--FCYKL 143 PGDRV + P + G + S + + + DG F+ N A L Sbjct: 77 PGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGEFFHVNDADMNLAHL 136 Query: 144 PDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVV 202 P + E +I + ++ G H + LG V V G GP+G++ + AK GA +++ Sbjct: 137 PKEIPLEAAVMIPDMMTTGFHGAELADIELGATVAVLGIGPVGLMAVAGAKLRGAGRIIA 196 Query: 203 TDLSATRLSKAKEIGADLVLQISKESPQE--IARKVEGQLGCKPEVTIECTGAEASIQA- 259 + AK GA ++ K+ P E I EG+ G + G A I A Sbjct: 197 VGSRPVCVDAAKYYGATDIVN-YKDGPIESQIMNLTEGK-GVDAAI---IAGGNADIMAT 251 Query: 260 GIYATRSGGNLVLVGLGSEMTTVPL----LHAAIREVDIKGVFRYCNTWPVA--ISMLAS 313 + + GG + V E +P+ + IKG + I ++ Sbjct: 252 AVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKTIKGGLCPGGRLRMERLIDLVFY 311 Query: 314 KSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSD 354 K V+ LVTH F F+ +K +++K P D Sbjct: 312 KRVDPSKLVTHVF------RGFDNIEKAF---MLMKDKPKD 343 >1H2B-A nrPDB Length = 359 Score = 87.8 bits (216), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 75/284 (26%), Positives = 130/284 (45%), Gaps = 12/284 (4%) Query: 20 LRLENYPIPE-PGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEK 78 LR+E+ P G +V++R+ G+C +D+H + K P LGHE G +E+ Sbjct: 28 LRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPKLPYTLGHENVGYIEE 87 Query: 79 VGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAA 138 V V+ L+ GD V + P C+ G ++ F D G F + + Sbjct: 88 VAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEFPGLNID-GGFAEFMRTSHR 146 Query: 139 FCYKLPDNVTFEEGALIEPLS-VGIHACR---RGGVTL--GHKVLVCGAGPIGMVTLLVA 192 KLP +++ E+ + PL+ GI A R + TL G V + G G +G + + + Sbjct: 147 SVIKLPKDISREKLVEMAPLADAGITAYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLL 206 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTG 252 K M A V+ D+ +L A+ +GAD V+ ++ +++ G+ V ++ G Sbjct: 207 KVMTPATVIALDVKEEKLKLAERLGADHVVDARRDPVKQVMELTRGR---GVNVAMDFVG 263 Query: 253 AEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKG 296 ++A++ Y G L++VG G E+ P + EV +G Sbjct: 264 SQATVDYTPYLLGRMGRLIIVGYGGEL-RFPTIRVISSEVSFEG 306 >3S2F-A nrPDB Length = 340 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 80/287 (27%), Positives = 130/287 (45%), Gaps = 26/287 (9%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMVLGHEASGTVE 77 L ++ P+P+PGP +V +++ + G+C +D+H + G++ VK P + GHE G V Sbjct: 15 LTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAAD----GDWPVKPTLPFIPGHEGVGYVS 70 Query: 78 KVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD-----DGNLCRF 132 VGS V +K GDRV G P C + L C + +G + Sbjct: 71 AVGSGVSRVKEGDRV----GVPWLYSA-CGYCEHCLQGWETLCEKQQNTGYSVNGGYGEY 125 Query: 133 YKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTL---GHKVLVCGAGPIGMVTL 189 + + LPD V F E A I L G+ + VT G V++ G G +G V + Sbjct: 126 VVADPNYVGLLPDKVGFVEIAPI--LCAGVTVYKGLKVTDTRPGQWVVISGIGGLGHVAV 183 Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249 A+AMG +V D+ +L+ A+ +GA++ + P +K ++G V + Sbjct: 184 QYARAMG-LRVAAVDIDDAKLNLARRLGAEVAVNARDTDPAAWLQK---EIGGAHGVLVT 239 Query: 250 CTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKG 296 +A QA I R GG + L GL P+ ++ + I+G Sbjct: 240 AVSPKAFSQA-IGMVRRGGTIALNGLPPGDFGTPIFDVVLKGITIRG 285 >3FPC-A nrPDB Length = 352 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/218 (29%), Positives = 102/218 (46%), Gaps = 9/218 (4%) Query: 28 PEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLK 87 P PGP + ++R +V C SD+H G IG + M+LGHEA G V +VGS VK K Sbjct: 20 PAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGE---RHNMILGHEAVGEVVEVGSEVKDFK 76 Query: 88 PGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDGNLCRFYKHNAA--FCYKL 143 PGDRV + P + G + S + + + DG F+ N A L Sbjct: 77 PGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGEFFHVNDADMNLAHL 136 Query: 144 PDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVV 202 P + E +I + ++ G H + LG V V G GP+G++++ A +GA ++ Sbjct: 137 PKEIPLEAAVMIPDMMTTGFHGAELANIKLGDTVCVIGIGPVGLMSVAGANHLGAGRIFA 196 Query: 203 TDLSATRLSKAKEIGA-DLVLQISKESPQEIARKVEGQ 239 A E GA D++ + + ++I + +G+ Sbjct: 197 VGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGK 234 >1E3E-A nrPDB Length = 376 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 93/370 (25%), Positives = 161/370 (43%), Gaps = 57/370 (15%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 L +E + P EV +++ + +C +D++ + + F P+VLGHE +G VE V Sbjct: 21 LCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKALF----PVVLGHECAGIVESV 76 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCAT------PPDDGNL---- 129 G V + KPGD+V I AP+ CK + LSP C P D L Sbjct: 77 GPGVTNFKPGDKV-IPFFAPQ-----CKRCKLCLSPLTNLCGKLRNFKYPTIDQELMEDR 130 Query: 130 -----CR------------FYKHNA---AFCYKLPDNVTFEEGALIEP-LSVGI-HACRR 167 C+ F ++ A ++ D E LI S G A Sbjct: 131 TSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFSSGYGAAINT 190 Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKE 227 VT G V G G +G+ ++ K GA++++ D++ + KAK +GA L Sbjct: 191 AKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALGATDCL----- 245 Query: 228 SPQEIARKVEGQL----GCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSEMTTV 282 +P+E+ + V+ + + +++C G +++A + T G G+ +VG + T+ Sbjct: 246 NPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKVDEMTI 305 Query: 283 PLLHAAIREVDIKGVF----RYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETF 338 P + + I G F + ++ P +S +K ++ LVTH P E +A + Sbjct: 306 PTVDVILGR-SINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESINDAIDLM 364 Query: 339 KKGLGLKIML 348 K+G ++ +L Sbjct: 365 KEGKSIRTIL 374 >1D1T-A nrPDB Length = 373 Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 92/356 (25%), Positives = 152/356 (42%), Gaps = 32/356 (8%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 +E + P EV +++ + GIC +D H + G + K P+++GHEA+G VE + Sbjct: 21 FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIK----GTMVSKFPVIVGHEATGIVESI 76 Query: 80 GSSVKHLKPGDRV-------AIEPGAPREND-EFCK----MGRYNLSPSI--FFCATPP- 124 G V +KPGD+V E A R D C GR L+ F C P Sbjct: 77 GEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPV 136 Query: 125 ----DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIE-PLSVGI-HACRRGGVTLGHKVLV 178 + + + + K+ D E+ LI S G A + G V G +V Sbjct: 137 HHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVV 196 Query: 179 CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEG 238 G G +G+ ++ K+ GA++++ DL+ + KA +GA + K+S + I+ + Sbjct: 197 FGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-PKDSTKPISEVLSE 255 Query: 239 QLGCKPEVTIECTG-AEASIQAGIYATRSGGNLVLVGL---GSEMTTVPLLHAAIREVD- 293 G T E G E I A + G V+VG+ +T P+L R Sbjct: 256 MTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKG 315 Query: 294 -IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 + G + + P ++ +K ++ L+TH P +K E FE G ++ +L Sbjct: 316 CVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVL 371 >4Z6K-A nrPDB Length = 346 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 86/330 (26%), Positives = 145/330 (43%), Gaps = 24/330 (7%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVK--KPMVLGHEASGTVE 77 L++E IP PG E++++M + G+C +D+H E G++ VK P + GHE G + Sbjct: 13 LQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVE----GDWPVKPSPPFIPGHEGVGLIT 68 Query: 78 KVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD-----DGNLCRF 132 VG V H+K GDRV + C + L C + + +G+ + Sbjct: 69 AVGEGVTHVKEGDRVGVAWLYSA-----CGHCTHCLGGWETLCESQQNSGYSVNGSFAEY 123 Query: 133 YKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGMVTLLV 191 NA + +P++V E A + V ++ + G V++ G G +G + + Sbjct: 124 VLANANYVGIIPESVDSIEIAPVLCAGVTVYKGLKMTDTKPGDWVVISGIGGLGHMAVQY 183 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECT 251 A AMG V D+ +L+ AK++GA + + P E +K ++G + Sbjct: 184 AIAMG-LNVAAVDIDDDKLAFAKKLGAKVTVNAKNTDPAEYLQK---EIGGAHGALVTAV 239 Query: 252 GAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISML 311 A+A QA + R GG LV GL V + + + I+G + S+ Sbjct: 240 SAKAFDQA-LSMLRRGGTLVCNGLPPGDFPVSIFDTVLNGITIRGSI-VGTRLDLQESLD 297 Query: 312 ASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 + + VK VT PLE + FE ++G Sbjct: 298 MAAAGKVKATVTAE-PLENINDIFERMRQG 326 >4DLA-A nrPDB Length = 396 Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 90/360 (25%), Positives = 148/360 (41%), Gaps = 37/360 (10%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 L +E+ + P EV +++ +C +D + W P VLGHEA+G VE V Sbjct: 39 LVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEGLF---PCVLGHEAAGIVESV 95 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD---DGNLCRFYKHN 136 G V ++PGD V A +FCK G+ NL + AT + RF N Sbjct: 96 GEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKV-RAATGVGVMMNDRKSRF-SIN 153 Query: 137 AAFCYKLPDNVTFEEGALIEPLSV---------------------GIHAC-RRGGVTLGH 174 Y TF + ++ +SV G+ A V G Sbjct: 154 GKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPTGLGAVWNTAKVEPGS 213 Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 234 V V G G +G+ AKA GA++++ D+ + + +AK G + KE Q I + Sbjct: 214 IVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVTEFIN-PKEHEQPIQQ 272 Query: 235 KVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL---GSEMTTVP--LLHAA 288 + + + EC G + +++ + G G V+VG+ G E++T P L+ Sbjct: 273 VIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASGQEISTRPFQLVTGR 332 Query: 289 IREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 + + G F+ + P + K + V +TH L +AF+ G L+++L Sbjct: 333 VWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKAFDLMHDGDCLRVVL 392 >5ENV-A nrPDB Length = 347 Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 72/263 (27%), Positives = 124/263 (47%), Gaps = 13/263 (4%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF--IVKKPMVLGHEASGT 75 G L ++ P+P+P NE+L+ + G+C +D+H W G++ VK P+V GHE +G Sbjct: 16 GKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWH----GDWPLPVKLPLVGGHEGAGV 71 Query: 76 VEKVGSSVKHLKPGDRVAIEP-GAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYK 134 V +G +VK K GD I+ E+C++G + P DG+ ++ Sbjct: 72 VVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLSGY-THDGSFQQYAT 130 Query: 135 HNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCG-AGPIGMVTLLVA 192 +A +P + A I + ++ A + + GH V + G AG +G + + A Sbjct: 131 ADAVQAAHIPQGTDLAQVAPILCAGITVYKALKSANLMAGHWVAISGAAGGLGSLAVQYA 190 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTG 252 KAMG +V+ D + + IG ++ + +KE ++I V I + Sbjct: 191 KAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTKE--KDIVGAVLKATDGGAHGVINVSV 247 Query: 253 AEASIQAGIYATRSGGNLVLVGL 275 +EA+I+A R+ G VLVG+ Sbjct: 248 SEAAIEASTRYVRANGTTVLVGM 270 >3FSR-A nrPDB Length = 352 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 61/201 (30%), Positives = 93/201 (46%), Gaps = 8/201 (3%) Query: 28 PEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLK 87 P PGP + ++R +V C SD+H G IG + M+LGHEA G V +VGS VK K Sbjct: 20 PAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGE---RHNMILGHEAVGEVVEVGSEVKDFK 76 Query: 88 PGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDGNLCRFYKHNAA--FCYKL 143 PGDRV + P + G + S + + + DG F+ N A L Sbjct: 77 PGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGEFFHVNDADMNLAHL 136 Query: 144 PDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVV 202 P + E +I + ++ G H + +G V+V G G +G++ + AK GA +++ Sbjct: 137 PKEIPLEAAVMIPDMMTTGFHGAELADIQMGSSVVVIGIGAVGLMGIAGAKLRGAGRIIG 196 Query: 203 TDLSATRLSKAKEIGADLVLQ 223 + AK GA +L Sbjct: 197 VGSRPICVEAAKFYGATDILN 217 >4RQU-A nrPDB Length = 375 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 101/371 (27%), Positives = 157/371 (42%), Gaps = 59/371 (15%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWE-YGRIGNFIVKKPMVLGHEASGTVEK 78 L +E + P +EV +++ +C +DV++WE G+ F P + GHEA G VE Sbjct: 18 LVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLF----PRIFGHEAGGIVES 73 Query: 79 VGSSVKHLKPGDRV----AIEPGAPR----ENDEFCKMGRYNLSPSIFFCATPPDDGNLC 130 VG V L+PGD V E G R E C + R N DG Sbjct: 74 VGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGMI-----HDGE-S 127 Query: 131 RFYKHNAAFCYKLPDNVTFEEGALIE-----------PLS-VGIHACRRG---GVTL--- 172 RF N Y TF E ++ PL V I +C G TL Sbjct: 128 RF-SINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGATLNVA 186 Query: 173 ----GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIG-ADLVLQISKE 227 G V + G G +G+ A+ GA++++ D ++ R +AKE G + V + Sbjct: 187 KPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVNPKDHD 246 Query: 228 SP--QEIARKVEGQLGCKPEVTIECTGA-EASIQAGIYATRSGGNLVLVGLGSE---MTT 281 P Q IA +G + + ++ECTG+ +A IQA G VLVG+ S+ T Sbjct: 247 KPIQQVIAEMTDGGV----DRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFKT 302 Query: 282 VPLLHAAIREVDIKGVF----RYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFET 337 P+ + E +KG F + P + +K + ++ +TH P + +AF+ Sbjct: 303 HPM--NFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDY 360 Query: 338 FKKGLGLKIML 348 KG ++ ++ Sbjct: 361 MLKGESIRCII 371 >1CDO-A nrPDB Length = 374 Score = 80.9 bits (198), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 90/367 (24%), Positives = 157/367 (42%), Gaps = 53/367 (14%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 L +E + P NE+ +++ + G+C +D+++ G+ + P+VLGHE +G VE V Sbjct: 21 LVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKDGF---PVVLGHEGAGIVESV 77 Query: 80 GSSVKHLKPGDRV----AIEPG------APRENDEFCKMGRYNLSPSIFFCATPPDDGNL 129 G V +PG++V + G +P+ N C G N SP + +P + Sbjct: 78 GPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQ--CVKGWANESPDVM---SPKETRFT 132 Query: 130 CR------FYKHNAAFCYKLPDNVTFEEGALIEP---------LSVGIH-----ACRRGG 169 C+ F + Y + + + A I+P L G+ A Sbjct: 133 CKGRKVLQFLGTSTFSQYTVVNQIAV---AKIDPSAPLDTVCLLGCGVSTGFGAAVNTAK 189 Query: 170 VTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGA-DLVLQISKES 228 V G V G G +G+ ++ + GA +++ DL+ + KAK GA D V Sbjct: 190 VEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATDFVNPNDHSE 249 Query: 229 P--QEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGS--EMTTVP 283 P Q +++ G + + ++EC G ++ + + G G VLVG ++ T P Sbjct: 250 PISQVLSKMTNGGV----DFSLECVGNVGVMRNALESCLKGWGVSVLVGWTDLHDVATRP 305 Query: 284 LLHAAIREV--DIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 + A R + G F+ + P + K V + +THR PLE +A + K G Sbjct: 306 IQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAIDLMKHG 365 Query: 342 LGLKIML 348 ++ +L Sbjct: 366 KCIRTVL 372 >3MEQ-A nrPDB Length = 365 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/214 (30%), Positives = 101/214 (47%), Gaps = 22/214 (10%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMVLGHEASGTVE 77 L ++ PIP+PGP ++ + + + G+C +D+H E G++ VK P + GHE G V Sbjct: 38 LTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAE----GDWPVKPNPPFIPGHEGVGFVS 93 Query: 78 KVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD-----DGNLCRF 132 VGS VKH+K GDRV I P C R+ L C + +G + Sbjct: 94 AVGSGVKHVKEGDRVGI----PWLYTA-CGHCRHCLGGWETLCEEQLNTGYSVNGGFAEY 148 Query: 133 YKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTL---GHKVLVCGAGPIGMVTL 189 + F LP N+ F E A + L G+ + VT G V++ G G +G + + Sbjct: 149 VVADPNFVGHLPKNIDFNEIAPV--LCAGVTVYKGLKVTDTKPGDWVVISGIGGLGHMAV 206 Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQ 223 A+AMG V D+ +L A+ +GA + + Sbjct: 207 QYARAMG-LNVAAVDIDDRKLDLARRLGATVTVN 239 >3FPL-A nrPDB Length = 351 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 75/265 (28%), Positives = 117/265 (44%), Gaps = 16/265 (6%) Query: 28 PEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLK 87 P G + ++R +V C SD+H G +G+ +K M+LGHEA G V +VGS VK K Sbjct: 20 PVAGSYDAIVRPLAVSPCTSDIHTVFEGALGD---RKNMILGHEAVGEVVEVGSEVKDFK 76 Query: 88 PGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDGNLCRFYKHNAA--FCYKL 143 PGDRV + P + G S + + + DG ++ N A L Sbjct: 77 PGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGVFGEYFHVNDADMNLAIL 136 Query: 144 PDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVV 202 P ++ E +I + ++ G H + LG V V G GP+G++ + AK GA +++ Sbjct: 137 PKDMPLENAVMITDMMTTGFHGAELADIELGATVAVLGIGPVGLMAVAGAKLRGAGRIIA 196 Query: 203 TDLSATRLSKAKEIGADLVLQISKESPQE--IARKVEGQLGCKPEVTIECTGAEASIQA- 259 + AK GA ++ K+ P E I EG+ G + G A I A Sbjct: 197 VGSRPVCVDAAKYYGATDIVN-YKDGPIESQIMNLTEGK-GVDAAI---IAGGNADIMAT 251 Query: 260 GIYATRSGGNLVLVGLGSEMTTVPL 284 + + GG + V E +P+ Sbjct: 252 AVKIVKPGGTIANVNYFGEGEVLPV 276 >2OUI-A nrPDB Length = 360 Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 87/341 (25%), Positives = 147/341 (43%), Gaps = 19/341 (5%) Query: 12 LVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHE 71 L + G G + IPE GP + L+R ++ C SD H G IG+ + M+LGHE Sbjct: 4 LAMLGIGRIGWIEKKIPECGPLDALVRPLALAPCTSDTHTVWAGAIGD---RHDMILGHE 60 Query: 72 ASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDGNL 129 A G + KVGS VK LK GD+V + P +E + G S + + + DG Sbjct: 61 AVGQIVKVGSLVKRLKVGDKVIVPAITPDWGEEESQRGYPMHSGGMLGGWKFSNFKDGVF 120 Query: 130 CRFYKHNAAFCY--KLPDNVTFEEGALIEPL-SVGIHACRRGGVTLGHKVLVCGAGPIGM 186 + N A LP ++ E+ ++ + + G H + LG V V G GP+G+ Sbjct: 121 SEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGAELANIKLGDTVCVIGIGPVGL 180 Query: 187 VTLLVAKAMGAAQVVVTDLSATRLSKAKEIGA-DLVLQISKESPQEIARKVEGQLGCKPE 245 +++ A +GA ++ A E GA D++ + + ++I + +G+ + Sbjct: 181 MSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGK--GVDK 238 Query: 246 VTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL----LHAAIREVDIKGVFRYC 301 V I QA + + G ++ V E +P+ + I G Sbjct: 239 VVIAGGDVHTFAQA-VKMIKPGSDIGNVNYLGEGDNIPIPRSEWGVGMGHKHIHGGLTPG 297 Query: 302 NTWPVA--ISMLASKSVNVKPLVTHRFP-LEKALEAFETFK 339 + S++++ ++ L+THRF LEK +A K Sbjct: 298 GRVRMEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMK 338 >4JJI-A nrPDB Length = 378 Score = 78.2 bits (191), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 86/360 (23%), Positives = 150/360 (41%), Gaps = 37/360 (10%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 L +E+ + P EV +++ +C +D + W G+ + P +LGHEA+G VE V Sbjct: 21 LVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWS-GKDPEGLF--PCILGHEAAGIVESV 77 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD---DGNLCRFYKHN 136 G V ++ GD V A +FCK G+ NL + AT + RF N Sbjct: 78 GEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKV-RSATGVGIMMNDRKSRF-SVN 135 Query: 137 AAFCYKLPDNVTFEEGALIEPLSV---------------------GIHAC-RRGGVTLGH 174 Y TF + ++ +SV G+ A V G Sbjct: 136 GKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPTGLGAVWNTAKVEPGS 195 Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 234 V + G G +G+ AK GA++++ D+ + + AK+ G + + K+ + I Sbjct: 196 NVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVNEFVN-PKDHDKPIQE 254 Query: 235 KVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL---GSEMTTVP--LLHAA 288 + + + EC G + ++A + G G V+VG+ G E++T P L+ Sbjct: 255 VIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASGQEISTRPFQLVTGR 314 Query: 289 IREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 + + G F+ P + +K + V +TH L + +AF+ +G L+ +L Sbjct: 315 VWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKAFDLLHEGTCLRCVL 374 >6FG0-A nrPDB Length = 352 Score = 77.8 bits (190), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 70/259 (27%), Positives = 115/259 (44%), Gaps = 11/259 (4%) Query: 24 NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSV 83 + P P PGP E+LL++ + G+C SD+ + + P+ LGHE GTV ++G V Sbjct: 17 DIPTPTPGPGEILLKVTAAGLCHSDITVMDM-PAAQYAGGLPLTLGHEGVGTVAELGEGV 75 Query: 84 KHLKPGDRVAIEPGAPRENDEFCKMGRYNL-SPSIFFCATPPDDGNLCRFYKH----NAA 138 GD VA+ C GR N + + TPP G+ ++ +A Sbjct: 76 TGFGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGITPPGYGSPGSMAEYMIVDSAR 135 Query: 139 FCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLG--HKVLVCGAGPIGMVTLLVAKAMG 196 + D L + HA R LG +V G G +G V + + +A+ Sbjct: 136 HLVPIGDLDPVAAAPLTDAGLTPYHAISRVLPLLGPGSTAVVIGVGGLGHVGIQILRAVS 195 Query: 197 AAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEAS 256 AA+V+ DL RL+ A+E+GAD ++ S + R++ G G + GA+++ Sbjct: 196 AARVIAVDLDDDRLALAREVGADAAVK-SGAGAADAIRELTGGQGAT--AVFDFVGAQST 252 Query: 257 IQAGIYATRSGGNLVLVGL 275 I G++ +VG+ Sbjct: 253 IDTAQQVVAVDGHISVVGI 271 >1F8F-A nrPDB Length = 371 Score = 77.8 bits (190), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 77/281 (27%), Positives = 126/281 (44%), Gaps = 34/281 (12%) Query: 19 DLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEK 78 D L+ I +P +EVL+++ + G+C +D+ R + V P VLGHE SG +E Sbjct: 18 DFELQALKIRQPQGDEVLVKVVATGMCHTDLIV----RDQKYPVPLPAVLGHEGSGIIEA 73 Query: 79 VGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDGN--LC---- 130 +G +V L+ GD V + G + + C G F + +GN LC Sbjct: 74 IGPNVTELQVGDHVVLSYGYCGKCTQ-CNTGNPAYCSEFFGRNFSGADSEGNHALCTHDQ 132 Query: 131 -----RFYKHNAAFCYKLP---DNVTFEEGALIE---PLSVGIH----ACRRG-GVTLGH 174 F+ ++ Y L + V + IE PL GI AC VT Sbjct: 133 GVVNDHFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACINALKVTPAS 192 Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 234 + GAG +G+ LL AK GA+ ++ D+ +RL AK++GA V+ + P + Sbjct: 193 SFVTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSKTQDPVAAIK 252 Query: 235 KV-EGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVG 274 ++ +G + +E TG+ ++ G+ A G + +VG Sbjct: 253 EITDGGV----NFALESTGSPEILKQGVDALGILGKIAVVG 289 >4RVS-A nrPDB Length = 329 Score = 77.4 bits (189), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 94/357 (26%), Positives = 150/357 (42%), Gaps = 64/357 (17%) Query: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGT 75 GPG LR + P P+PG E+L++ ++G+ D ++ R G + + P V+G E GT Sbjct: 12 GPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYF----RSGQYPRELPFVIGSEVCGT 67 Query: 76 VEKVGSSV----KHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCR 131 VE VG V + GDRV + N + + FC P Sbjct: 68 VEAVGPGVTAADTAISVGDRVV----SASANGAYAE-----------FCTAP-------- 104 Query: 132 FYKHNAAFCYKLPDNVTFE--EGALIEPLSV-----GIHACRRGGVTLGHKVLVCGAGPI 184 A+ K+PD+VT E AL++ L+ ++ +RG L H GAG + Sbjct: 105 -----ASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVH----AGAGGV 155 Query: 185 GMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 G++ A +G +V+ T +A + +K+ GAD+VL +++ Q R E G Sbjct: 156 GLILTQWATHLG-VRVITTVSTAEKAKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGV 214 Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVP------LLHAAIREVDIKGVF 298 + + GA + A + + G L L G S VP L A + +F Sbjct: 215 QAVYDGVGA-TTFDASLASLAVRGTLALFGAAS--GPVPPVDPQRLNAAGSVYLTRPSLF 271 Query: 299 RYCNT-----WPVAISMLASKSVNVKPLVTHRFPLEKALEAFETF--KKGLGLKIML 348 + T W A A + + V R+PL AL A + +K +G ++L Sbjct: 272 HFTRTGEEFSWRAAELFDAIGNEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLL 328 >2DPH-A nrPDB Length = 398 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 83/278 (29%), Positives = 122/278 (43%), Gaps = 45/278 (16%) Query: 9 NLSLVVHGPGDLRLENYPIPEPGPNE------VLLRMHSVGICGSDVHYWEYGRIGNFIV 62 N S+V HG DLR+E P P+ N V+L++ S ICGSD H + G FIV Sbjct: 3 NKSVVYHGTRDLRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSDQHIYR----GRFIV 58 Query: 63 KKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF---- 118 K VLGHE +G V + GS V+ + GD V++ CK R ++ + Sbjct: 59 PKGHVLGHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCENNLVNPD 118 Query: 119 -------------------FCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLS 159 + P D L +F A K+ D +T + + L Sbjct: 119 ADLGAFGFDLKGWSGGQAEYVLVPYADYMLLKFGDKEQAM-EKIKD-LTL----ISDILP 172 Query: 160 VGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGAD 219 G H C GV G V + GAGP+G A+ +GAA V+V D + RL + G + Sbjct: 173 TGFHGCVSAGVKPGSHVYIAGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGFE 232 Query: 220 LVLQISKESPQEIARKVEGQLGCKPEVT--IECTGAEA 255 + + +P + +++ LG KPEV ++ G EA Sbjct: 233 -TIDLRNSAP--LRDQIDQILG-KPEVDCGVDAVGFEA 266 >2H6E-A nrPDB Length = 344 Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 75/328 (22%), Positives = 146/328 (44%), Gaps = 15/328 (4%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 L +E+ IPEP EVL+R+ G+C +D+ W+ G + P++LGHE +GT+ +V Sbjct: 16 LSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWK-GVEAKQGFRLPIILGHENAGTIVEV 74 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAF 139 G K +K GD V + +C+ G++N+ + + G ++ + Sbjct: 75 GELAK-VKKGDNVVVYATWGDLTCRYCREGKFNICKNQIIPGQTTNGGFSEYMLVKSSRW 133 Query: 140 CYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGH----KVLVCGAGPIGMVTLLVAKAM 195 KL E L + + + A R+ + V+V G G + + T+ + KA+ Sbjct: 134 LVKLNSLSPVEAAPLADAGTTSMGAIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKAL 193 Query: 196 GAAQVVVTDLSATRLSK--AKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGA 253 + + +S ++ + A E+GAD V ++ + + + K+ LG + I+ G Sbjct: 194 -MKNITIVGISRSKKHRDFALELGADYVSEM--KDAESLINKLTDGLGA--SIAIDLVGT 248 Query: 254 EASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLAS 313 E + G ++LVG+ + ++ A+ + G Y + + + S Sbjct: 249 EETTYNLGKLLAQEGAIILVGMEGKRVSLEAFDTAVWNKKLLGS-NYGSLNDLEDVVRLS 307 Query: 314 KSVNVKPLVTHRFPLEKALEAFETFKKG 341 +S +KP + + PL+ +AF +G Sbjct: 308 ESGKIKPYII-KVPLDDINKAFTNLDEG 334 >1KEV-A nrPDB Length = 351 Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 58/201 (28%), Positives = 93/201 (46%), Gaps = 8/201 (3%) Query: 28 PEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLK 87 P G + ++R +V C SD+H G +G+ +K M+LGHEA G V +VGS VK K Sbjct: 20 PVAGSYDAIVRPLAVSPCTSDIHTVFEGALGD---RKNMILGHEAVGEVVEVGSEVKDFK 76 Query: 88 PGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDGNLCRFYKHNAA--FCYKL 143 PGDRV + P + G S + + + DG ++ N A L Sbjct: 77 PGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGVFGEYFHVNDADMNLAIL 136 Query: 144 PDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVV 202 P ++ E +I + ++ G H + +G V+V G G +G++ + AK GA +++ Sbjct: 137 PKDMPLENAVMITDMMTTGFHGAELADIQMGSSVVVIGIGAVGLMGIAGAKLRGAGRIIG 196 Query: 203 TDLSATRLSKAKEIGADLVLQ 223 + AK GA +L Sbjct: 197 VGSRPICVEAAKFYGATDILN 217 >6N7L-A nrPDB Length = 353 Score = 74.3 bits (181), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 88/339 (25%), Positives = 145/339 (42%), Gaps = 28/339 (8%) Query: 13 VVHGPGD-LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIV--KKPMVLG 69 VV G G+ L+++ P+ EPG EVL+++ + G+C +D+H + G++ K P++ G Sbjct: 18 VVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVD----GDWPAKPKMPLIPG 73 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD---- 125 HE G V G +K GD V G P C Y ++ C + Sbjct: 74 HEGVGIVVACGPDA-MVKEGDAV----GVPWLYSA-CGCCDYCITGWETLCEAQQNGGYS 127 Query: 126 -DGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGP 183 DG + ++ + L NV F E A I V ++ + G V + G G Sbjct: 128 VDGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVYKGLKETETKPGEWVAISGIGG 187 Query: 184 IGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESP-QEIARKVEGQLGC 242 +G V + AKAMG V D++ +L AK++GADL + P + ++V G G Sbjct: 188 LGHVAVQYAKAMG-MHVAAIDVADDKLELAKKLGADLTVNAKTTDPGTYLHKEVGGMHG- 245 Query: 243 KPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCN 302 + + + + GI R G + L GL +P+ ++ + ++G Sbjct: 246 ----ALITAVSPIAFKQGIDVLRRKGTIALNGLPPGSFELPIFETVLKRITVRGSIVGTR 301 Query: 303 TWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 A++ + VK VT LE + F+ KKG Sbjct: 302 KDLQEALDFANEGL-VKATVTSA-KLEDINDVFDKMKKG 338 >1P0F-A nrPDB Length = 373 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 97/378 (25%), Positives = 151/378 (39%), Gaps = 69/378 (18%) Query: 15 HGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASG 74 H P L LE + P +EV +++ + GICGSD + F P++LGHEA G Sbjct: 19 HKP--LSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPSKF----PVILGHEAVG 72 Query: 75 TVEKVGSSVKHLKPGDRV----AIEPGAPR----ENDEFC-------KMGRYNLSPSIFF 119 VE +G+ V +KPGD+V + G+ R N FC K G S F Sbjct: 73 VVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAKTGLMADMTSRFT 132 Query: 120 CATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVG-------IHACRRG---- 168 C P Y L TF E ++ ++V + +C G Sbjct: 133 CRGKP---------------IYNLMGTSTFTEYTVVADIAVAKIDPKAPLESCLIGCGFA 177 Query: 169 ----------GVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGA 218 VT G V G G +G ++ KA GA++++ + KA E+GA Sbjct: 178 TGYGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGA 237 Query: 219 DLVLQ---ISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVG 274 L K + I K G + + +EC G ++ + +T G G V++G Sbjct: 238 TECLNPKDYDKPIYEVICEKTNGGV----DYAVECAGRIETMMNALQSTYCGSGVTVVLG 293 Query: 275 LGS-EMTTVPLLHAAIREVDIKG-VFRYCNTWPVA--ISMLASKSVNVKPLVTHRFPLEK 330 L S + +KG VF V+ + K +NV LV+ + L++ Sbjct: 294 LASPNERLPLDPLLLLTGRSLKGSVFGGFKGEEVSRLVDDYMKKKINVNFLVSTKLTLDQ 353 Query: 331 ALEAFETFKKGLGLKIML 348 +AFE G G++ ++ Sbjct: 354 INKAFELLSSGQGVRSIM 371 >4JLW-A nrPDB Length = 399 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 81/279 (29%), Positives = 126/279 (45%), Gaps = 47/279 (16%) Query: 9 NLSLVVHGPGDLRLENYPIP---EPGPNE----VLLRMHSVGICGSDVHYWEYGRIGNFI 61 N +V GPG + ++N P P +P + V+LR+ S ICGSD H G Sbjct: 4 NRGVVYLGPGKVEVQNIPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVR----GRTT 59 Query: 62 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAI-----------------------EPGA 98 + +VLGHE +G V ++G V+ +K GD V++ P Sbjct: 60 APEGLVLGHEITGEVVEIGRGVETMKIGDLVSVPFNVACGHCRTCKEQHTGVCLTVNPAR 119 Query: 99 PRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPL 158 + MG + + + P D NL + AA K+ D L + L Sbjct: 120 AGGAYGYVDMGGW-VGGQAEYVLVPYADFNLLKLPNREAAM-EKIRDLT-----CLSDIL 172 Query: 159 SVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGA 218 G H GV G V + GAGP+G+ A+ +GAA V+V D++ TRL+ AK+ G Sbjct: 173 PTGYHGAVTAGVGPGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQGF 232 Query: 219 DLVLQISKESPQEIARKVEGQLGCKPEV--TIECTGAEA 255 ++ +SK++P + ++ LG +PEV ++ G EA Sbjct: 233 EIA-DLSKDTP--LHEQIAALLG-EPEVDCAVDAVGFEA 267 >5TNX-A nrPDB Length = 383 Score = 72.4 bits (176), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 79/282 (28%), Positives = 115/282 (40%), Gaps = 38/282 (13%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 +E I P +EVL+R+ + G+C +D+ R + V P VLGHE +G VE V Sbjct: 30 FSIEPARIRAPRGDEVLVRVVATGLCHTDLIV----RDQYYPVPLPAVLGHEGAGVVEAV 85 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF---FCATPPDDGNLCR----- 131 G +VK L GD V + GA C G F F D R Sbjct: 86 GPNVKTLAAGDHVVLTYGACGHCAS-CAGGHGAYCRQFFALNFGGADADGQTALRDAAGE 144 Query: 132 -----FYKHNAAFCY---------KLPDNVTFEEGALIEPLSVGIHA-----CRRGGVTL 172 F+ ++ Y K+P E L+ PL GI V Sbjct: 145 PLHDHFFAQSSFASYALARENNAIKVPKEAPLE---LLGPLGCGIQTGAGAVINSLAVRT 201 Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 G GAG +GM ++ A+ GA ++ D+ +RL+ A E+GA + SKE ++ Sbjct: 202 GSSFASFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAIN-SKEV--DV 258 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVG 274 + G + +E TG A + GI A S G + +VG Sbjct: 259 VDAIREITGGGVDYALESTGLPAVLSQGIDALGSRGTMGVVG 300 >1MC5-A nrPDB Length = 374 Score = 71.2 bits (173), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 88/367 (23%), Positives = 157/367 (42%), Gaps = 50/367 (13%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGR-IGNFIVKKPMVLGHEASGTVEK 78 L +E + P +EV +++ + +C +D + G F P++LGHE +G VE Sbjct: 20 LSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF----PVILGHEGAGIVES 75 Query: 79 VGSSVKHLKPGDRVAIEPGAPREND-EFCKMGRYNLSPSIFFCATP---PD-------DG 127 VG V LK GD V I P+ + +FC + NL I PD G Sbjct: 76 VGEGVTKLKAGDTV-IPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKG 134 Query: 128 NLCRFYKHNAAFC-YKLPDNVTFEEGALIEPLSVGIHACRRG-GVTLGHKVL-------- 177 Y + F Y + +++ A I+PL+ C G G++ G+ Sbjct: 135 KTILHYMGTSTFSEYTVVADISV---AKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEP 191 Query: 178 --VC---GAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 VC G G +G+ ++ K GA++++ D++ + ++AKE GA + +PQ+ Sbjct: 192 GSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI-----NPQDF 246 Query: 233 ARKVEGQL----GCKPEVTIECTGAEASIQAGIYATRSG----GNLVLVGLGSEMTTVP- 283 ++ ++ L + + EC G ++A + A G + + G E+ T P Sbjct: 247 SKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPF 306 Query: 284 -LLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 L+ + G ++ + P +S SK + V VTH ++ +AFE G Sbjct: 307 QLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGK 366 Query: 343 GLKIMLK 349 ++ ++K Sbjct: 367 SIRTVVK 373 >4GKV-A nrPDB Length = 336 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 74/267 (27%), Positives = 125/267 (46%), Gaps = 15/267 (5%) Query: 34 EVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVA 93 E LL+M G+C +D+H + G+F K ++LGHE G V +VG V LKPGDR + Sbjct: 26 EALLKMECCGVCHTDLHV----KNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRAS 81 Query: 94 IE---PGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFE 150 + G + E+C G L S+ A DG + A + K+PD + Sbjct: 82 VAWFYEGCG--HCEYCNSGNETLCRSVKN-AGYSVDGGMAEECIVVADYAVKVPDGLDSA 138 Query: 151 EGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATR 209 + I V + A + + G + + G G +G + L AK + A+V+ D++ + Sbjct: 139 AASSITCAGVTTYKAVKLSKIRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQ 198 Query: 210 LSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGN 269 L A E+GADL + E +I ++ G + A+A+ + + A R+GG Sbjct: 199 LKLATEMGADLAINSHTEDAAKIVQEKTG----GAHAAVVTAVAKAAFNSAVDAVRAGGR 254 Query: 270 LVLVGLGSEMTTVPLLHAAIREVDIKG 296 +V VGL E ++ + + +++ G Sbjct: 255 VVAVGLPPESMSLDIPRLVLDGIEVVG 281 >3UOG-A nrPDB Length = 363 Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 75/277 (27%), Positives = 117/277 (42%), Gaps = 44/277 (15%) Query: 17 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTV 76 P DL+L P+PE G +++++R +V + D E G + P V + SG V Sbjct: 38 PHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGM--GLDLAFPFVPASDMSGVV 95 Query: 77 EKVGSSVKHLKPGDRV----------AIEPGAPRENDEFCKMG--------RYNLSPSIF 118 E VG SV +PGDRV + PG R + +G Y + P + Sbjct: 96 EAVGKSVTRFRPGDRVISTFAPGWLDGLRPGTGR-TPAYETLGGAHPGVLSEYVVLPEGW 154 Query: 119 FCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLV 178 F A P +AA LP AL+E +G + G +V+V Sbjct: 155 FVAAPK---------SLDAAEASTLPCAGLTAWFALVE----------KGHLRAGDRVVV 195 Query: 179 CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEG 238 G G + + L +AKA G A+V+VT S +L +A +GAD + +E E + G Sbjct: 196 QGTGGVALFGLQIAKATG-AEVIVTSSSREKLDRAFALGADHGINRLEEDWVERVYALTG 254 Query: 239 QLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGL 275 G + +E G A + + A G + ++G+ Sbjct: 255 DRGA--DHILEIAGG-AGLGQSLKAVAPDGRISVIGV 288 >5YAT-A nrPDB Length = 350 Score = 68.2 bits (165), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 72/288 (25%), Positives = 137/288 (47%), Gaps = 16/288 (5%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIV--KKPMVLGHEASGT 75 G L ++ P+P+P NE+L+ + G+C +D+H W+ G++ + K P+V GHE +G Sbjct: 19 GPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWK----GDWPLDNKLPLVGGHEGAGV 74 Query: 76 VEKVGSSVKHLKPGDRVAIEP-GAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYK 134 V G +V + GD I+ N E+C G + S + + DG+ ++ Sbjct: 75 VVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAES-SCAKADLSGFTHDGSFQQYAT 133 Query: 135 HNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGMVTLL-VA 192 +A ++P E A I + ++ A + + +G V + GAG + A Sbjct: 134 ADATQAARIPKEADLAEVAPILCAGITVYKALKTADLRIGQWVAISGAGGGLGSLAVQYA 193 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTG 252 KA+G +V+ D A + K +GA++ + +K +++ +V+ P I + Sbjct: 194 KALG-LRVLGIDGGADKGEFVKSLGAEVFVDFTK--TKDVVAEVQKLTNGGPHGVINVSV 250 Query: 253 AEASIQAGIYATRSGGNLVLVGL--GSEMTTVPLLHAAIREVDIKGVF 298 + +I + R+ G +VLVGL G+ + + H ++ ++IKG + Sbjct: 251 SPHAINQSVQYVRTLGKVVLVGLPSGAVVNSDVFWH-VLKSIEIKGSY 297 >3WLE-A nrPDB Length = 341 Score = 64.3 bits (155), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 82/293 (27%), Positives = 130/293 (44%), Gaps = 23/293 (7%) Query: 12 LVVHGPGDLRLEN-YPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGH 70 V + L+L N P+ +P ++LL++ +VG+C SD+H G V+GH Sbjct: 15 FVFNKQSGLKLRNDLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEG----LDCGDNYVMGH 70 Query: 71 EASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDGN 128 E +GTV VG V + K GDRVA ++C+ N+ + F + D G Sbjct: 71 EIAGTVAAVGDDVINYKVGDRVACVGPNGCGGCKYCRGAIDNVCKNAFGDWFGLGYDGGY 130 Query: 129 LCRFYKHNAAFCYKLPDNVTFE-EGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMV 187 ++PDNV+ + A + + HA + V+ +L+ GAG +G Sbjct: 131 QQYLLVTRPRNLSRIPDNVSADVAAASTDAVLTPYHAIKMAQVSPTSNILLIGAGGLGGN 190 Query: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKE--SPQEIARKVEGQLGCKPE 245 + VAKA G A+V V D +AK++GAD V + E SP + C Sbjct: 191 AIQVAKAFG-AKVTVLDKKKEARDQAKKLGADAVYETLPESISPGSFS-------ACFDF 242 Query: 246 VTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVF 298 V++ +A+ G ++ VGLG+ + L A+RE+ I G F Sbjct: 243 VSV-----QATFDVCQKYVEPKGVIMPVGLGAPNLSFNLGDLALREIRILGSF 290 >4A10-A nrPDB Length = 447 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 77/299 (25%), Positives = 122/299 (40%), Gaps = 50/299 (16%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHY---W--------------EYGRIGNFIV 62 LRL P+PE P+EVL V + S ++Y W + R G + Sbjct: 50 LRLGEVPMPELAPDEVL-----VAVMASSINYNTVWSAMFEPIPTFHFLKQNARQGGWAT 104 Query: 63 KKPM---VLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFF 119 + VLG + SG V + G V+ KPGD V + P A + E G L Sbjct: 105 RHDQPYHVLGSDCSGVVVRTGIGVRRWKPGDHVIVHP-AHVDEQEPATHGDGMLGTEQRA 163 Query: 120 CATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVG-----IHACRRGGVTLGH 174 + G L + A+ P ++T+EE A + PL G + + R + G Sbjct: 164 WGFETNFGGLAEYGVVRASQLLPKPAHLTWEEAA-VSPLCAGTAYRMLVSDRGAQMKQGD 222 Query: 175 KVLVCGA-GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK------- 226 VL+ GA G +G + K G V V SA + + + +G DLV+ ++ Sbjct: 223 IVLIWGASGGLGSYAIQFVKNGGGIPVAVVS-SAQKEAAVRALGCDLVINRAELGITDDI 281 Query: 227 --------ESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGS 277 E+ +++A+ V + G +P++ E TG + + R GG +V G S Sbjct: 282 ADDPRRVVETGRKLAKLVVEKAGREPDIVFEHTG-RVTFGLSVIVARRGGTVVTCGSSS 339 >3FBG-A nrPDB Length = 346 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 55/217 (25%), Positives = 91/217 (41%), Gaps = 47/217 (21%) Query: 24 NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSV 83 N IPEP +E+L+++ S+ + D R+ + + K P VLG +A G VE VG+ V Sbjct: 24 NLDIPEPKVHEILVKIQSISVNPVDTK----QRLMD-VSKAPRVLGFDAIGVVESVGNEV 78 Query: 84 KHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKL 143 GD V ++ +P +G+ + N K Sbjct: 79 TMFNQGDIV-------------------------YYSGSPDQNGSNAEYQLINERLVAKA 113 Query: 144 PDNVTFEEG------------ALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLV 191 P N++ E+ L + + + G TL +++ GAG +G + + Sbjct: 114 PKNISAEQAVSLPLTGITAYETLFDVFGISRNRNENEGKTL---LIINGAGGVGSIATQI 170 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKES 228 AKA G +V+ T + K++GAD+VL KES Sbjct: 171 AKAYG-LRVITTASRNETIEWTKKMGADIVLN-HKES 205 >3QWB-A nrPDB Length = 334 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 32/218 (14%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWE-YGRIGNFIVKKPMVLGHEASGTVEK 78 ++ E+YP+P E+L++ G V+Y E Y R G + +KP VLG EASGTV Sbjct: 23 IKYEDYPVPSISEEELLIKNKYTG-----VNYIESYFRKGIYPCEKPYVLGREASGTVVA 77 Query: 79 VGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAA 138 G V + + GD+VA N F + + + + D L K AA Sbjct: 78 KGKGVTNFEVGDQVAY-----ISNSTFAQYSKISSQGPVMKLPKGTSDEEL----KLYAA 128 Query: 139 FCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAA 198 ++ ++F A + ++G L L AG +G++ + K GA Sbjct: 129 GLLQVLTALSFTNEA---------YHVKKGDYVL----LFAAAGGVGLILNQLLKMKGAH 175 Query: 199 QVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKV 236 + V + +L AKE GA+ ++ SKE +I R+V Sbjct: 176 TIAVAS-TDEKLKIAKEYGAEYLINASKE---DILRQV 209 >1KOL-A nrPDB Length = 398 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 70/246 (28%), Positives = 108/246 (43%), Gaps = 40/246 (16%) Query: 35 VLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAI 94 V+L++ S ICGSD H G + +VLGHE +G V + G V++L+ GD V++ Sbjct: 36 VILKVVSTNICGSDQHMVR----GRTTAQVGLVLGHEITGEVIEKGRDVENLQIGDLVSV 91 Query: 95 -----------------------EPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCR 131 P + MG + + + P D NL + Sbjct: 92 PFNVACGRCRSCKEMHTGVCLTVNPARAGGAYGYVDMGDWTGGQAEYVL-VPYADFNLLK 150 Query: 132 FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLV 191 + A K+ D L + L G H GV G V V GAGP+G+ Sbjct: 151 LPDRDKAM-EKIRDLT-----CLSDILPTGYHGAVTAGVGPGSTVYVAGAGPVGLAAAAS 204 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEV--TIE 249 A+ +GAA V+V DL+ RL+ AK G ++ +S ++P + ++ LG +PEV ++ Sbjct: 205 ARLLGAAVVIVGDLNPARLAHAKAQGFEIA-DLSLDTP--LHEQIAALLG-EPEVDCAVD 260 Query: 250 CTGAEA 255 G EA Sbjct: 261 AVGFEA 266 >1YB5-A nrPDB Length = 351 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 84/339 (24%), Positives = 140/339 (41%), Gaps = 47/339 (13%) Query: 16 GPGDLRLE-NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMVLGHEA 72 GP L+L + +P P ++VL+++H+ G+ + Y R G + K P G + Sbjct: 40 GPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVET----YIRSGTYSRKPLLPYTPGSDV 95 Query: 73 SGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRF 132 +G +E VG + K GDRV F +T G + Sbjct: 96 AGVIEAVGDNASAFKKGDRV-------------------------FTSSTI--SGGYAEY 128 Query: 133 YKHNAAFCYKLPDNVTFEEGALIE-PLSVGIHACRRGG-VTLGHKVLVCGA-GPIGMVTL 189 YKLP+ + F++GA I P A V G VLV GA G +G+ Sbjct: 129 ALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAAC 188 Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249 +A+A G +++ T + + GA V + + + +K G+ G ++ IE Sbjct: 189 QIARAYGL-KILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGI--DIIIE 245 Query: 250 CTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNT----WP 305 A ++ + GG +++VG + P A +E I GV + +T Sbjct: 246 ML-ANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMA-KESSIIGVTLFSSTKEEFQQ 303 Query: 306 VAISMLASKSVN-VKPLVTHRFPLEKALEAFETFKKGLG 343 A ++ A + +KP++ ++PLEK EA E G G Sbjct: 304 YAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSG 342 >3JYN-A nrPDB Length = 325 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 63/226 (27%), Positives = 97/226 (42%), Gaps = 37/226 (16%) Query: 14 VHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEAS 73 V GP L ++ PGP V++R ++G+ D +Y F+ P LG E + Sbjct: 10 VGGPEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPFL---PSGLGAEGA 66 Query: 74 GTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFY 133 G VE VG V K GDRVA G E + NL Sbjct: 67 GVVEAVGDEVTRFKVGDRVAYGTGPLGAYSEVHVLPEANL-------------------- 106 Query: 134 KHNAAFCYKLPDNVTFEEGA--LIEPLSVGIHACRRGGVTLGHKVLV-CGAGPIGMVTLL 190 KL D+V+FE+ A +++ L+V + V G +L AG +G + Sbjct: 107 -------VKLADSVSFEQAAALMLKGLTVQYLLRQTYQVKPGEIILFHAAAGGVGSLACQ 159 Query: 191 VAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKV 236 AKA+G A+++ T S + + AK +GA + S E ++A++V Sbjct: 160 WAKALG-AKLIGTVSSPEKAAHAKALGAWETIDYSHE---DVAKRV 201 >1Q1N-A nrPDB Length = 360 Score = 53.9 bits (128), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 93/345 (26%), Positives = 149/345 (43%), Gaps = 60/345 (17%) Query: 29 EPGP---NEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVG-SSVK 84 +P P +++ +++ + G+CGSD+H G GN +K P+V+GHE G V K+G S Sbjct: 27 DPKPFYDHDIDIKIEACGVCGSDIH-CAAGHWGN--MKMPLVVGHEIVGKVVKLGPKSNS 83 Query: 85 HLKPGDRVAIEPGAPRENDEFCKMGRYNLSPS----IFFCATPPDDG--------NLCRF 132 LK G RV + GA + C + + P + + P +DG N R Sbjct: 84 GLKVGQRVGV--GAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDGYVSQGGYANYVRV 141 Query: 133 YKHNAAFCYKLPDNVTFEEGALIEPLSVG----IHACRRGGVTLGHKVLVCGAGPIGMVT 188 ++H F +P+N+ L PL G R G G KV + G G IG + Sbjct: 142 HEH---FVVPIPENIP---SHLAAPLLCGGLTVYSPLVRNGCGPGKKVGIVGLGGIGSMG 195 Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP---- 244 L++KAMGA V++ S R A ++GAD IA EG G K Sbjct: 196 TLISKAMGAETYVISRSSRKR-EDAMKMGAD----------HYIATLEEGDWGEKYFDTF 244 Query: 245 EVTIECTGAEASIQAGIY--ATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIK----GVF 298 ++ + C + I I A + GG +V + + + + L ++ V I G Sbjct: 245 DLIVVCASSLTDIDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPYGLKAVSISYSALGSI 304 Query: 299 RYCNTWPVAISMLASKSVNVKPLVTHRFPLEKA--LEAFETFKKG 341 + N + +++ K + + P+ +A EAFE +KG Sbjct: 305 KELNQ---LLKLVSEKDIKI---WVETLPVGEAGVHEAFERMEKG 343 >4OAQ-A nrPDB Length = 367 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 53/210 (25%), Positives = 92/210 (43%), Gaps = 15/210 (7%) Query: 21 RLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVG 80 +L +Y + P++V+L+ G+C SD+H G + + +V+GHE G V VG Sbjct: 24 KLASYERKQINPHDVVLKNEVCGLCYSDIHTLSAG--WQPLQRDNLVVGHEIIGEVIAVG 81 Query: 81 SSVKHLKPGDRVAIEPGAP---------RENDEFCKMGRYNLSPSIFFCATPPDDGNLCR 131 V K GDRV I + +N+++CK G + G Sbjct: 82 DEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYCKQGAATYNSKDVRSNNYVTQGGYSS 141 Query: 132 FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHA--CRRGGVTL-GHKVLVCGAGPIGMVT 188 + F + +P+++ GA + + + + R G+ G V + G G +G + Sbjct: 142 HSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNLGLDARGKNVGIIGIGGLGHLA 201 Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGA 218 L A AMG A V S+++ +A ++GA Sbjct: 202 LQFANAMG-ANVTAFSRSSSKKEQAMKLGA 230 >3TWO-A nrPDB Length = 348 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 62/260 (23%), Positives = 101/260 (38%), Gaps = 36/260 (13%) Query: 31 GPNEVLLRMHSVGICGSDVHY----WEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHL 86 GP +VL+ + GIC SD+H W+ G PM+ GHE +G +++VG VK Sbjct: 28 GPRDVLIDILYAGICHSDIHSAYSEWKEGIY-------PMIPGHEIAGIIKEVGKGVKKF 80 Query: 87 KPGDRVAI----------EPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHN 136 K GD V + +P ++FC + F P G + Sbjct: 81 KIGDVVGVGCFVNSCKACKP-CKEHQEQFCTKVVFTYDCLDSFHDNEPHMGGYSNNIVVD 139 Query: 137 AAFCYKLPDNVTFEEGALIEPLSVGIHA-CRRGGVTLGHKVLVCGAGPIGMVTLLVAKAM 195 + + N E+ A + + ++ + VT G KV V G G +G + + A AM Sbjct: 140 ENYVISVDKNAPLEKVAPLLCAGITTYSPLKFSKVTKGTKVGVAGFGGLGSMAVKYAVAM 199 Query: 196 GAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEA 255 G A+V V + + A +G K+ +E+ + I Sbjct: 200 G-AEVSVFARNEHKKQDALSMGVKHFYTDPKQCKEEL------------DFIISTIPTHY 246 Query: 256 SIQAGIYATRSGGNLVLVGL 275 ++ + G+L LVGL Sbjct: 247 DLKDYLKLLTYNGDLALVGL 266 >1QOR-A nrPDB Length = 327 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 66/241 (27%), Positives = 104/241 (43%), Gaps = 38/241 (15%) Query: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK-PMVLGHEASG 74 GP L+ + +P NE+ + ++GI D Y R G + P LG EA+G Sbjct: 12 GPEVLQAVEFTPADPAENEIQVENKAIGINFIDT----YIRSGLYPPPSLPSGLGTEAAG 67 Query: 75 TVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYK 134 V KVGS VKH+K GDRV A +G Y+ +I Sbjct: 68 IVSKVGSGVKHIKAGDRVVYAQSA---------LGAYSSVHNII---------------A 103 Query: 135 HNAAFCYKLPDNVTFEEGA--LIEPLSVGIHACRRGGVTLGHKVLV-CGAGPIGMVTLLV 191 AA LP ++FE+ A ++ L+V + + + L AG +G++ Sbjct: 104 DKAAI---LPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQW 160 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECT 251 AKA+G A+++ T +A + A + GA V+ +E E +++ G G K V + Sbjct: 161 AKALG-AKLIGTVGTAQKAQSALKAGAWQVINYREEDLVERLKEITG--GKKVRVVYDSV 217 Query: 252 G 252 G Sbjct: 218 G 218 >4A27-A nrPDB Length = 349 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 43/138 (31%), Positives = 60/138 (43%), Gaps = 30/138 (21%) Query: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGT 75 G LRL +PEP E+ +R+ + G+ D+ + G I N K P+V G E SG Sbjct: 14 GLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQ-GNIDN-PPKTPLVPGFECSGI 71 Query: 76 VEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKH 135 VE +G SVK + GDRV M N + TP + Sbjct: 72 VEALGDSVKGYEIGDRV---------------MAFVNYNAWAEVVCTPVE---------- 106 Query: 136 NAAFCYKLPDNVTFEEGA 153 F YK+PD+++F E A Sbjct: 107 ---FVYKIPDDMSFSEAA 121 >4EYE-A nrPDB Length = 342 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 88/351 (25%), Positives = 137/351 (39%), Gaps = 71/351 (20%) Query: 14 VHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSD--VHYWEYGRIGNFIVKKPMVLGHE 71 + GP L + P GPN V++ + + G+C D + EY ++ P V G E Sbjct: 30 LSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGEY----QLKMEPPFVPGIE 85 Query: 72 ASGTVEKV--GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYN----LSPSIFFCATPP- 124 +G V GS +K PGDRV F +G Y ++PS TPP Sbjct: 86 TAGVVRSAPEGSGIK---PGDRVM----------AFNFIGGYAERVAVAPSNIL-PTPPQ 131 Query: 125 -DDGNLCRFYK--HNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA 181 DD H F Y RRG + G VLV GA Sbjct: 132 LDDAEAVALIANYHTMYFAY-----------------------ARRGQLRAGETVLVLGA 168 Query: 182 GPIGMVTLL-VAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL 240 + +AK MGA + V + +A K +GAD+VL + +E + R+ G Sbjct: 169 AGGIGTAAIQIAKGMGAKVIAVVNRTAAT-EFVKSVGADIVLPL-EEGWAKAVREATGGA 226 Query: 241 GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGS-EMTTVPLLHAAIREVDIKGV-- 297 G ++ ++ G A A + S G L++VG + + T+ + +R + GV Sbjct: 227 GV--DMVVDPIGGPAFDDA-VRTLASEGRLLVVGFAAGGIPTIKVNRLLLRNASLIGVAW 283 Query: 298 -------FRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 Y + L ++ ++P V+ R PL + +A + F G Sbjct: 284 GEFLRTHADYLYETQAGLEKLVAE--GMRPPVSARIPLSEGRQALQDFADG 332 >1YQX-A nrPDB Length = 366 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 71/271 (26%), Positives = 115/271 (42%), Gaps = 29/271 (10%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHY----WEYGRIGNFIVKKPMVLGHEAS 73 G L N+ G +V ++ G+C SD+H W + P+V GHE Sbjct: 27 GHLSPFNFSRRATGEEDVRFKVLYCGVCHSDLHSIKNDWGFSMY-------PLVPGHEIV 79 Query: 74 GTVEKVGSSVKHLKPGDRVAIE--PGAPRENDEFCKMGRYNLSPSIFFC-ATPPDDGNLC 130 G V +VGS VK + GD+V + GA E C N P + A+ DG + Sbjct: 80 GEVTEVGSKVKKVNVGDKVGVGCLVGACHSC-ESCANDLENYCPKMILTYASIYHDGTIT 138 Query: 131 R--FYKH---NAAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGHKVLVCGAGP 183 + H N + + PDN+ + GA + + +++ + G G + + G G Sbjct: 139 YGGYSNHMVANERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGG 198 Query: 184 IGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCK 243 +G V + AKA G+ V++ + + K GAD L +S++ QE + G L Sbjct: 199 LGHVAVKFAKAFGSKVTVISTSPSKKEEALKNFGADSFL-VSRD--QEQMQAAAGTL--- 252 Query: 244 PEVTIECTGAEASIQAGIYATRSGGNLVLVG 274 + I+ A + +S G L+LVG Sbjct: 253 -DGIIDTVSAVHPLLPLFGLLKSHGKLILVG 282 >3TQH-A nrPDB Length = 321 Score = 47.8 bits (112), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 56/217 (25%), Positives = 93/217 (42%), Gaps = 32/217 (14%) Query: 17 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK-----PMVLGHE 71 P L+L + P PE N++L+++H+ + D ++ F+ KK P LG++ Sbjct: 18 PKVLKLVDTPTPEYRKNQMLIKVHAASLNPID---YKTRNGSGFVAKKLKNNLPSGLGYD 74 Query: 72 ASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCR 131 SG V ++GS V ++ GD+V G P D C Y CA+P D + + Sbjct: 75 FSGEVIELGSDVNNVNIGDKVMGIAGFP---DHPCCYAEY-------VCASP--DTIIQK 122 Query: 132 FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLV 191 K + LP L ++ ++G V L H GAG +G + + + Sbjct: 123 LEKLSFLQAASLP------TAGLTALQALNQAEVKQGDVVLIH----AGAGGVGHLAIQL 172 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKES 228 AK G V+T S + K +GA+ + +E Sbjct: 173 AKQKGTT--VITTASKRNHAFLKALGAEQCINYHEED 207 >5H82-A nrPDB Length = 389 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 65/247 (26%), Positives = 99/247 (40%), Gaps = 42/247 (17%) Query: 31 GPNEVLLRMHSVGICGSDVHYWE--YGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKP 88 G ++V ++ G+C DV + YG K P V GHE G V ++G+ VK K Sbjct: 52 GEHDVQFKVLYCGLCDWDVITTKNTYG-----TTKYPFVPGHEIMGIVTEIGNKVKKFKV 106 Query: 89 GDRVAIEPGAPREND-EFCKMGRYNLSPSIFFC--ATPPDDGNLC----------RFYK- 134 GD+V + E C G P + + D+ N R Y Sbjct: 107 GDKVGVGNFIGSCGKCERCNEGLEPYCPKVIYTDGTAFSDENNTVYGDVSGDGEDRIYGG 166 Query: 135 ------HNAAFCYKLPDNVTFEEG-----ALIEPLSVGIH-ACRRGGVTLGHKVLVCGAG 182 N ++ P+N+ G I P S H + G+++G V G G Sbjct: 167 YSNIMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIG----VVGFG 222 Query: 183 PIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIA---RKVEGQ 239 IG + + AKA GA V++ + + ++ G D L ISKE P+E+ ++G Sbjct: 223 RIGKLAVKFAKAFGANVTVISTSISKKQEAIEKYGVDRFL-ISKE-PEEMKAAESTLDGI 280 Query: 240 LGCKPEV 246 C P V Sbjct: 281 FDCVPSV 287 >1WLY-A nrPDB Length = 333 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 55/241 (22%), Positives = 101/241 (41%), Gaps = 38/241 (15%) Query: 10 LSLVVH---GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKP- 65 ++ V+H GP + E + PGP +V LR ++G+ D Y G +V +P Sbjct: 3 MAAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDT-YHRAGIPHPLVVGEPP 61 Query: 66 MVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD 125 +V+G EA+ VE+VG V G+RV C P Sbjct: 62 IVVGFEAAAVVEEVGPGVTDFTVGERV---------------------------CTCLPP 94 Query: 126 DGNLCRFYKHNAAFCYKLPDNVTFEE----GALIEPLSVGIHACRRGGVTLGHKVLV-CG 180 G + + A K+P ++ ++ G +++ ++ + V G VL+ Sbjct: 95 LGAYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMTAQYLLHQTHKVKPGDYVLIHAA 154 Query: 181 AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL 240 AG +G + + A+ +GA V+ T + + A+++G + S + E+ R++ G Sbjct: 155 AGGMGHIMVPWARHLGAT-VIGTVSTEEKAETARKLGCHHTINYSTQDFAEVVREITGGK 213 Query: 241 G 241 G Sbjct: 214 G 214 >1UUF-A nrPDB Length = 369 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 60/212 (28%), Positives = 83/212 (39%), Gaps = 28/212 (13%) Query: 29 EPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKP 88 EPGPN+V + + G+C SD+H G P V GHE G V VG V+ P Sbjct: 44 EPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVY---PCVPGHEIVGRVVAVGDQVEKYAP 100 Query: 89 GDRVAIEPGAPR-ENDEFCKMGRYNLSPSI---FFCATPPDDGNLCRFYKHNAAFC--YK 142 GD V + ++ E C+ G N + + TP + G+ Y Y Sbjct: 101 GDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYV 160 Query: 143 LPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGM-----------VTLLV 191 L E+ A + PL G+T + AGP + + + Sbjct: 161 LRIRHPQEQLAAVAPLLC-------AGITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKL 213 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQ 223 A AMGA V T A R AK +GAD V+ Sbjct: 214 AHAMGAHVVAFTTSEAKR-EAAKALGADEVVN 244 >2VWH-A nrPDB Length = 357 Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 51/179 (28%), Positives = 77/179 (43%), Gaps = 15/179 (8%) Query: 26 PIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKH 85 P PEP E L+R VG+ G+D G G + +VLGHEA G V V + Sbjct: 19 PRPEPESGEALVRTLRVGVDGTDHEVIAGGHGGFPEGEDHLVLGHEAVGVV--VDPNDTE 76 Query: 86 LKPGDRV---AIEPGAPRENDEFCKMGRYNLSPS--IFFCATPPDDGNLCRFYKHNAAFC 140 L+ GD V P A N E+ + + +++P F G + F+ + Sbjct: 77 LEEGDIVVPTVRRPPASGTN-EYFERDQPDMAPDGMYFERGIVGAHGYMSEFFTSPEKYL 135 Query: 141 YKLPDNVTFEEGALIEPLSVG------IHACRRGGVTLGHKVLVCGAGPIGMVTLLVAK 193 ++P + E G LIEP+S+ +A R V G G +G++TL + K Sbjct: 136 VRIPRSQA-ELGFLIEPISITEKALEHAYASRSAFDWDPSSAFVLGNGSLGLLTLAMLK 193 >5FI5-A nrPDB Length = 357 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 61/220 (27%), Positives = 95/220 (43%), Gaps = 26/220 (11%) Query: 24 NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSV 83 N+ G ++V L++ G C D E + P VLGHE G V +VGS V Sbjct: 34 NFSRRATGEHDVQLKVLYCGTCQYD---REMSKNKFGFTSYPYVLGHEIVGEVTEVGSKV 90 Query: 84 KHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKH-------N 136 + K GD+V + + E C+M + +C P+ G++ Y N Sbjct: 91 QKFKVGDKVGV--ASIIETCGKCEMCTNEVEN---YC---PEAGSIDSNYGACSNIAVIN 142 Query: 137 AAFCYKLPDNVTFEEGALIEPLSVGIHAC----RRGGVTLGHKVLVCGAGPIGMVTLLVA 192 F + P+N+ + G + L GI A R G G ++ + G G +G V L A Sbjct: 143 ENFVIRWPENLPLDSGVPL--LCAGITAYSPMKRYGLDKPGKRIGIAGLGGLGHVALRFA 200 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 KA GA V++ + ++ GAD L S +P+E+ Sbjct: 201 KAFGAKVTVISSSLKKKREAFEKFGADSFLVSS--NPEEM 238 >2VN8-A nrPDB Length = 375 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 79/356 (22%), Positives = 138/356 (38%), Gaps = 87/356 (24%) Query: 32 PNEVLLRMHSVGICGSDVHYWE-YGRIGNFIVKKPM-----------VLGHEASGTVEKV 79 PNEV++++H+ + DV+ YG + + P+ LG + SG V + Sbjct: 50 PNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMEC 109 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP-DDGNLCRFYKHNAA 138 G VK+ KPGD V + A PP G L F + Sbjct: 110 GLDVKYFKPGDEV--------------------------WAAVPPWKQGTLSEFVVVSGN 143 Query: 139 FCYKLPDNVTFEEGALIEPLSVGIHAC--RRGGVT----LGHKVLVCGA-GPIGMVTLLV 191 P ++T + A + +++ + + GG+ G +VL+ GA G +G + V Sbjct: 144 EVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQV 203 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP-EVTIEC 250 KA A V A+ L +++GAD V+ S +E + + KP + ++ Sbjct: 204 MKAWDAHVTAVCSQDASEL--VRKLGADDVIDYKSGSVEEQLKSL------KPFDFILDN 255 Query: 251 TGAEASIQAGIYATRSGG------------NLVLVGLGSEM--TTVPLLHAAIREVDIKG 296 G A + + G N+ +G+ M T V + A++ KG Sbjct: 256 VGGSTETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHF-WKG 314 Query: 297 V-FRYCNTWPVAISMLASKSVN----------VKPLVTHRFPLEKALEAFETFKKG 341 V +R+ A M + ++ ++P++ FP K EAF ++G Sbjct: 315 VHYRW------AFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERG 364 >2CDC-A nrPDB Length = 366 Score = 43.9 bits (102), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 78/321 (24%), Positives = 131/321 (40%), Gaps = 58/321 (18%) Query: 2 AAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI 61 A KP N + V + +L++Y ++ +R GICG+D G++ Sbjct: 3 AIIVKPPNAGVQVKDVDEKKLDSY-------GKIKIRTIYNGICGADREIVN-GKLTLST 54 Query: 62 V---KKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF 118 + K +VLGHEA G VE+ S GD V N C + R L Sbjct: 55 LPKGKDFLVLGHEAIGVVEE---SYHGFSQGDLVM------PVNRRGCGICRNCLVGRPD 105 Query: 119 FCAT--------PPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLS----------- 159 FC T DG + ++ + + K+P ++ + G L +PL+ Sbjct: 106 FCETGEFGEAGIHKMDGFMREWWYDDPKYLVKIPKSIE-DIGILAQPLADIEKSIEEILE 164 Query: 160 ----VGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE 215 V + C G + KVLV G GPIG++ L+ + G + T + + Sbjct: 165 VQKRVPVWTCDDGTLNC-RKVLVVGTGPIGVLFTLLFRTYGLEVWMANRREPTEVEQT-- 221 Query: 216 IGADLVLQISKESPQEIAR---KVEGQLGCKPEVTIECTGAEASIQAGIYATR-SGGNLV 271 V++ +K + + K++ +G K +V I+ TGA+ +I + G L Sbjct: 222 -----VIEETKTNYYNSSNGYDKLKDSVG-KFDVIIDATGADVNILGNVIPLLGRNGVLG 275 Query: 272 LVGLGSEMTTVPLLHAAIREV 292 L G S +VPL + ++E+ Sbjct: 276 LFGF-STSGSVPLDYKTLQEI 295 >3HZZ-A nrPDB Length = 467 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 68/297 (22%), Positives = 114/297 (38%), Gaps = 58/297 (19%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHY---W--------------EYGRIGNFIV 62 + L+ P+PE GP E L V + S V+Y W YG++ Sbjct: 76 IHLDEVPVPELGPGEAL-----VAVMASSVNYNSVWTSIFEPVSTFAFLERYGKLSPLTK 130 Query: 63 KKPM---VLGHEASGTVEKVGSSVKHLKPGDRV-----AIEPGAPRENDEFCKMGRYNLS 114 + + ++G + +G V + G V +PGD V ++E +P +D+ L Sbjct: 131 RHDLPYHIIGSDLAGVVLRTGPGVNAWQPGDEVVAHCLSVELESPDGHDDTM------LD 184 Query: 115 PSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGA---LIEPLSVGIHACRRG-GV 170 P + G L P ++T+EE A L+ + R G + Sbjct: 185 PEQRIWGFETNFGGLAEIALVKTNQLMPKPKHLTWEEAAAPGLVNSTAYRQLVSRNGAAM 244 Query: 171 TLGHKVLVCGA-GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKE-- 227 G VL+ GA G +G A A GA + V S + + +GA+ ++ + E Sbjct: 245 KQGDNVLIWGASGGLGSYATQFALAGGANPICVVS-SPQKAEICRSMGAEAIIDRNAEGY 303 Query: 228 ---------SPQEIAR---KVEGQLGCKP-EVTIECTGAEASIQAGIYATRSGGNLV 271 P+E R ++ G + ++ E G E + A +Y TR GG + Sbjct: 304 KFWKDEHTQDPKEWKRFGKRIRELTGGEDIDIVFEHPGRE-TFGASVYVTRKGGTIT 359 >5H83-A nrPDB Length = 360 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%) Query: 24 NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSV 83 N+ G N+V ++ G C D+ + G + K P V+GHE G V ++GS V Sbjct: 31 NFSRRATGENDVQFKVLYCGTCNYDLE-MSTNKFG--MTKYPFVIGHEIVGVVTEIGSKV 87 Query: 84 KHLKPGDRVAI 94 + K GD+V + Sbjct: 88 QKFKVGDKVGV 98 >3B70-A nrPDB Length = 371 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 40/150 (26%), Positives = 61/150 (40%), Gaps = 27/150 (18%) Query: 7 PNNLSLVVHGPGDLRLENY-PIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKP 65 P +L V+ ++ + N P P ++V +R+ +V I SD G F Sbjct: 10 PQQTALTVNDHDEVTVWNAAPCPMLPRDQVYVRVEAVAINPSDTKM-----RGQFATPW- 63 Query: 66 MVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD 125 LG + +GTV VGS V H++ GDRV GA E C PD Sbjct: 64 AFLGTDYAGTVVAVGSDVTHIQVGDRVY---GAQNE-----------------MCPRTPD 103 Query: 126 DGNLCRFYKHNAAFCYKLPDNVTFEEGALI 155 G ++ K+P ++FE+ A + Sbjct: 104 QGAFSQYTVTRGRVWAKIPKGLSFEQAAAL 133 >4J6F-A nrPDB Length = 382 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 56/238 (23%), Positives = 92/238 (38%), Gaps = 31/238 (13%) Query: 23 ENYPIPEPGPNEVLLRMHSVGICGSDVHYWE--YG------------RIGNFIVKKPMVL 68 + P+P P EVL+++ + G+ +DV E YG R GN + P + Sbjct: 52 RDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSAVSTWRRHGNTLT-FPRIQ 110 Query: 69 GHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGN 128 G + G + VG V + G+RV + +F R + S + DG Sbjct: 111 GTDTVGHIVAVGEGVDRARIGERVMV---------DFSIYNRDDDSLADIDYMGHGRDGG 161 Query: 129 LCRFYKHNAAFCYKLPDNVT-FEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA-GPIGM 186 + A + + ++T E G R + G VLV GA G +G Sbjct: 162 YAEYMALPAENAHVVATDLTDIELATFCCAYLTGERMLERARLAAGETVLVTGASGGVGS 221 Query: 187 VTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 + +A+A GA + V + + +IGA V+ ++A VE G +P Sbjct: 222 AIIQLARARGAVPIAVA--GPGKEAAMLDIGAQAVV---TRGQGDLAEAVEAASGGRP 274 >5Z0C-A nrPDB Length = 374 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 25/64 (39%), Positives = 34/64 (53%), Gaps = 3/64 (4%) Query: 31 GPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGD 90 G +V ++ GIC SD+HY + N I P + GHE G V +VGS V K GD Sbjct: 37 GELDVTFKVLYCGICHSDLHYIK-NEWSNTIY--PALPGHEIVGEVTEVGSKVNKFKVGD 93 Query: 91 RVAI 94 +V + Sbjct: 94 KVGV 97 >5A3V-A nrPDB Length = 329 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 8/83 (9%) Query: 15 HGPGDLRLENY--PIPEPGPNEVLLRMHSVGICGSDVHYW--EYGRIGNFIVKK-PMVLG 69 +G G LE+ P+P P NEV L++ + + D W + G I F+ +K P + Sbjct: 14 YGGGAAGLEHVQVPVPTPKSNEVCLKLEATSLNPVD---WKIQKGMIRPFLPRKFPCIPA 70 Query: 70 HEASGTVEKVGSSVKHLKPGDRV 92 + +G V +VGS VK+ K GD+V Sbjct: 71 TDVAGEVVEVGSGVKNFKAGDKV 93 >4IDE-A nrPDB Length = 332 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 56/250 (22%), Positives = 100/250 (40%), Gaps = 35/250 (14%) Query: 27 IPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHL 86 +PE ++VL+++ + + D G + P + G++ +G V KVGS V Sbjct: 47 VPEIKEDQVLIKVVAASLNPVDFKR-ALGYFKDTDSPLPTIPGYDVAGVVVKVGSQVTKF 105 Query: 87 KPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDN 146 K GD V G N + + P G+L + + P N Sbjct: 106 KVGDEV---------------YGDLNETALV----NPTRFGSLAEYTAADERVLAHKPKN 146 Query: 147 VTFEEGALIEPLSVGI--HACRRGGVTLGHKVLVCGAGPIGMVTLL-VAKAMGAAQVVVT 203 ++F E A + PL++ R ++ G VLV G ++ +AK + A V Sbjct: 147 LSFIEAASL-PLAIETAHEGLERAELSAGKSVLVLGGAGGVGTHIIQLAKHVFGASKVAA 205 Query: 204 DLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYA 263 S +L + +GADL + +KE+ +++ K +V + G + A Sbjct: 206 TASTKKLDLLRTLGADLAIDYTKENFEDLPEKF--------DVVYDAVG---ETDKAVKA 254 Query: 264 TRSGGNLVLV 273 + GG +V + Sbjct: 255 VKEGGKVVTI 264 >5VKT-A nrPDB Length = 362 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 4/96 (4%) Query: 31 GPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGD 90 G +V +++ GIC +D+H + GN + P+V GHE G V VG V K GD Sbjct: 33 GDADVTIKVLFCGICHTDLHVIK-NEWGNAMY--PVVPGHEVVGVVTDVGHGVTKFKAGD 89 Query: 91 RVAIEPGAPR-ENDEFCKMGRYNLSPSIFFCATPPD 125 V + E C G N P + + D Sbjct: 90 TVGVGYFVDSCRTCESCSTGHENYCPDLVLTSNGVD 125 >2WEK-A nrPDB Length = 341 Score = 35.8 bits (81), Expect = 0.027, Method: Compositional matrix adjust. Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 12/74 (16%) Query: 26 PIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTV--------- 76 P+P PG ++L+R VG+ SD++Y GR + VK P +G E G V Sbjct: 26 PVPLPGDGDLLVRNRFVGVNASDINYSA-GRY-DPSVKPPFDIGFEGIGEVVALGLSASA 83 Query: 77 -EKVGSSVKHLKPG 89 VG +V ++ PG Sbjct: 84 RYTVGQAVAYMAPG 97 >2VCY-A nrPDB Length = 344 Score = 34.3 bits (77), Expect = 0.076, Method: Compositional matrix adjust. Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 11/98 (11%) Query: 2 AAAAKPNNLSLVVHGP-GD----LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGR 56 +A+A+P + +V+G GD + L+N + ++V ++M + I SD++ + Sbjct: 6 SASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQ--- 62 Query: 57 IGNF--IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRV 92 GN+ + + P V G+E V VGS+V LKPGD V Sbjct: 63 -GNYGLLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWV 99 >6C49-A nrPDB Length = 350 Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 11/70 (15%) Query: 29 EPGPNEVLLRMHSVGICGSDV----HYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVK 84 E P++V +++ G+C SD+ + W P+V GHE G + +GS K Sbjct: 35 ELQPHQVEVKVEYCGLCHSDISVLNNEWHS-------TVYPVVAGHEIIGRIVALGSEAK 87 Query: 85 HLKPGDRVAI 94 L+ G RV I Sbjct: 88 GLQIGQRVGI 97 >2OBY-A nrPDB Length = 338 Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust. Identities = 59/253 (23%), Positives = 95/253 (37%), Gaps = 48/253 (18%) Query: 12 LVVH-----GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI--VKK 64 L VH GP +L ++ P PG EVLL++ + + +D+ R G + Sbjct: 8 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQ----RQGQYDPPPGA 63 Query: 65 PMVLGHEASGTVEKVGSSVK-HLKPGDR-VAIEPGAPRENDEFCKMGRYNLSPSIFFCAT 122 +LG EASG V ++G + H K GD +A+ PG Sbjct: 64 SNILGLEASGHVAELGPGCQGHWKIGDTAMALLPG------------------------- 98 Query: 123 PPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGHKVLV-C 179 G ++ +P+ +T + A I + G V G VL+ Sbjct: 99 ----GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHA 154 Query: 180 GAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQ 239 G +G + + + GA +VT S +L A+++GA KE E K Sbjct: 155 GLSGVGTAAIQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKG 213 Query: 240 LGCKPEVTIECTG 252 G + ++C G Sbjct: 214 AGVN--LILDCIG 224 >4DVJ-A nrPDB Length = 363 Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust. Identities = 45/225 (20%), Positives = 83/225 (36%), Gaps = 38/225 (16%) Query: 19 DLRLENYPIPEPGP--NEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTV 76 D L + +P+P P +++L+ + +V + D ++ R V+G++A+G V Sbjct: 37 DASLLDIELPKPAPAGHDILVEVKAVSVNPVD---YKVRRSTPPDGTDWKVIGYDAAGIV 93 Query: 77 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHN 136 VG V +PGD V F+ + G F+ + Sbjct: 94 SAVGPDVTLFRPGDEV-------------------------FYAGSIIRPGTNAEFHLVD 128 Query: 137 AAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKV--------LVCGAGPIGMVT 188 + P + + E A + S+ + + V +V GAG +G + Sbjct: 129 ERIVGRKPKTLDWAEAAALPLTSITAWEAFFDRLDVNKPVPGAAPAILIVGGAGGVGSIA 188 Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIA 233 + +A+ V+ T K +GA V+ SK E+A Sbjct: 189 VQIARQRTDLTVIATASRPETQEWVKSLGAHHVIDHSKPLAAEVA 233 >2CF5-A nrPDB Length = 357 Score = 31.6 bits (70), Expect = 0.52, Method: Compositional matrix adjust. Identities = 56/210 (26%), Positives = 93/210 (44%), Gaps = 22/210 (10%) Query: 24 NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGR-IGNFIVKKPMVLGHEASGTVEKVGSS 82 Y + E GP +V +R+ GIC +D+H + + N+ PMV GHE G V +VGS Sbjct: 26 TYTLRETGPEDVNIRIICCGICHTDLHQTKNDLGMSNY----PMVPGHEVVGEVVEVGSD 81 Query: 83 VKHLKPGD-------RVAIEPGAPREND--EFC--KMGRYNLSPSIFFCATPPDDGNLCR 131 V GD +P E D ++C K+ YN + P G + Sbjct: 82 VSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIWSYN----DVYINGQPTQGGFAK 137 Query: 132 FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHA--CRRGGVTLGHKVLVCGAGPIGMVTL 189 + F K+P+ + E+ A + V +++ G G + + G G +G + + Sbjct: 138 ATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGGILGLGGVGHMGV 197 Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGAD 219 +AKAMG V++ + R +++GAD Sbjct: 198 KIAKAMGHHVTVISSSNKKREEALQDLGAD 227 >2HPW-A nrPDB Length = 235 Score = 31.2 bits (69), Expect = 0.67, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Query: 105 FCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHA 164 FC +Y + FF +T PD + R + Y + VT+E G L ++V Sbjct: 72 FC-FAKYPRHIADFFKSTQPDGYSQDRIISFDNDGQYDVKAKVTYENGTLYNRVTVKGTG 130 Query: 165 CRRGGVTLGHKVL 177 + G LG +VL Sbjct: 131 FKSNGNILGMRVL 143 >4MAG-A nrPDB Length = 307 Score = 30.8 bits (68), Expect = 0.87, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 30/51 (58%), Gaps = 2/51 (3%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVL 68 G+++L YP + G + +L+ ++G D+ Y E+GR+G +I + V+ Sbjct: 33 GEIKLALYPSAQLGDDRAMLQQLTLGDL--DITYAEFGRMGLWIPRAEAVM 81 >1CS1-A nrPDB Length = 386 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 42/167 (25%), Positives = 65/167 (38%), Gaps = 19/167 (11%) Query: 191 VAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCK-PEVTIE 249 +A+ +GA VV + L +GADLVL + + V G + K P+V E Sbjct: 162 LAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTE 221 Query: 250 CTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAIS 309 +I G+ L+L GL T VP + A R + + + +Y T P+ Sbjct: 222 LAWWANNI--GVTGGAFDSYLLLRGL---RTLVPRMELAQR--NAQAIVKYLQTQPL--- 271 Query: 310 MLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQN 356 VK L P + E +KG G + + D +Q Sbjct: 272 --------VKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQT 310 >3WID-A nrPDB Length = 369 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 14/91 (15%) Query: 11 SLVVHGP-GDLRLENYPIPEPGPNEVLLRMHSVGICGSD------VHYWEYGRIG-NFIV 62 ++V P G ++ +PEP E L+ +GICG+D + Y G NF Sbjct: 6 AIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENF-- 63 Query: 63 KKPMVLGHEASGTVEKVGSSVKHLKPGDRVA 93 +VLGHEA V V S ++K GD V Sbjct: 64 ---LVLGHEALLQVLDV-SDNNYIKRGDFVV 90 >3MGG-A nrPDB Length = 276 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE 215 G KVL G G IG T+++AK A++ D+S L KA+E Sbjct: 38 GAKVLEAGCG-IGAQTVILAKNNPDAEITSIDISPESLEKARE 79 >6DEO-A nrPDB Length = 682 Score = 28.1 bits (61), Expect = 6.7, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 20/41 (48%) Query: 272 LVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLA 312 LV ++ T + A +E DI G+ R C W V + +A Sbjct: 179 LVVFSGQVPTTAIGTDAFQEADIVGISRSCTKWNVMVKNVA 219 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1PL8-A nrPDB 469 e-132 3QE3-A nrPDB 446 e-126 1E3J-A nrPDB 369 e-102 2DFV-A nrPDB 316 8e-87 3GFB-A nrPDB 315 2e-86 5VM2-A nrPDB 310 8e-85 3M6I-A nrPDB 307 4e-84 2DQ4-A nrPDB 306 1e-83 1HSO-A nrPDB 304 3e-83 5KIA-A nrPDB 299 1e-81 1HSZ-A nrPDB 299 1e-81 1U3W-A nrPDB 299 1e-81 1EE2-A nrPDB 291 3e-79 3PII-A nrPDB 288 3e-78 3COS-A nrPDB 285 2e-77 1E3E-A nrPDB 284 3e-77 2EER-A nrPDB 282 2e-76 4DLA-A nrPDB 281 4e-76 4JJI-A nrPDB 279 9e-76 4OH1-A nrPDB 277 4e-75 1D1T-A nrPDB 276 1e-74 1MC5-A nrPDB 274 3e-74 4ILK-A nrPDB 273 1e-73 1CDO-A nrPDB 273 1e-73 1LLU-A nrPDB 272 2e-73 4EJ6-A nrPDB 270 8e-73 4Z6K-A nrPDB 269 2e-72 4RQU-A nrPDB 267 6e-72 5YLN-A nrPDB 266 1e-71 6N7L-A nrPDB 266 1e-71 3MEQ-A nrPDB 265 2e-71 4CPD-A nrPDB 264 5e-71 3S2F-A nrPDB 260 6e-70 6DKH-A nrPDB 260 8e-70 1YKF-A nrPDB 254 6e-68 1R37-A nrPDB 253 1e-67 3FPC-A nrPDB 250 7e-67 4UEJ-A nrPDB 249 1e-66 3FSR-A nrPDB 249 2e-66 4EEZ-A nrPDB 248 3e-66 1H2B-A nrPDB 247 5e-66 3FPL-A nrPDB 247 5e-66 1P0F-A nrPDB 242 2e-64 1KEV-A nrPDB 242 2e-64 5ENV-A nrPDB 241 5e-64 5K1S-A nrPDB 240 7e-64 2OUI-A nrPDB 239 1e-63 3IP1-A nrPDB 236 8e-63 1F8F-A nrPDB 228 2e-60 5TNX-A nrPDB 226 9e-60 5YAT-A nrPDB 222 1e-58 4GKV-A nrPDB 221 4e-58 2H6E-A nrPDB 219 1e-57 6FG0-A nrPDB 214 7e-56 3WLE-A nrPDB 207 4e-54 3UOG-A nrPDB 205 2e-53 3TWO-A nrPDB 192 2e-49 1UUF-A nrPDB 191 3e-49 1YB5-A nrPDB 191 5e-49 4A10-A nrPDB 189 2e-48 1YQX-A nrPDB 187 9e-48 3HZZ-A nrPDB 183 1e-46 4RVS-A nrPDB 182 2e-46 1WLY-A nrPDB 182 3e-46 4J6F-A nrPDB 180 7e-46 5H82-A nrPDB 179 2e-45 3JYN-A nrPDB 178 4e-45 5Z0C-A nrPDB 178 4e-45 4OAQ-A nrPDB 175 2e-44 1Q1N-A nrPDB 173 1e-43 5FI5-A nrPDB 171 3e-43 3QWB-A nrPDB 171 3e-43 1QOR-A nrPDB 170 5e-43 2DPH-A nrPDB 163 9e-41 4JLW-A nrPDB 163 1e-40 5H83-A nrPDB 162 2e-40 3TQH-A nrPDB 155 3e-38 1KOL-A nrPDB 153 9e-38 2CDC-A nrPDB 152 3e-37 2VN8-A nrPDB 147 7e-36 4EYE-A nrPDB 147 9e-36 3FBG-A nrPDB 145 4e-35 2VWH-A nrPDB 144 5e-35 4A27-A nrPDB 126 2e-29 5A3V-A nrPDB 125 2e-29 3B70-A nrPDB 120 1e-27 Sequences not found previously or not previously below threshold: 6C49-A nrPDB 167 5e-42 5VKT-A nrPDB 166 2e-41 2CF5-A nrPDB 139 2e-33 4Y1B-A nrPDB 139 2e-33 2OBY-A nrPDB 137 7e-33 4IDE-A nrPDB 135 2e-32 4DVJ-A nrPDB 130 1e-30 2WEK-A nrPDB 119 1e-27 2VCY-A nrPDB 116 1e-26 3SLK-A nrPDB 102 4e-22 3WID-A nrPDB 96 3e-20 5LB9-A nrPDB 89 3e-18 5GXF-A nrPDB 84 1e-16 1O89-A nrPDB 79 2e-15 1V3V-A nrPDB 74 8e-14 2Y05-A nrPDB 69 4e-12 2VNA-A nrPDB 65 4e-11 2ZB3-A nrPDB 62 4e-10 2J3K-A nrPDB 58 6e-09 1XLT-A nrPDB 40 0.002 4DIO-A nrPDB 40 0.002 5EKU-A nrPDB 38 0.005 4M36-A nrPDB 38 0.005 2EGU-A nrPDB 38 0.005 3MGG-A nrPDB 38 0.005 4AEC-A nrPDB 38 0.007 1X14-A nrPDB 38 0.007 1ZCJ-A nrPDB 37 0.011 1W1U-A nrPDB 37 0.016 4N7R-A nrPDB 37 0.018 1I9G-A nrPDB 37 0.018 4OM8-A nrPDB 37 0.019 3ZWA-A nrPDB 37 0.019 2RIR-A nrPDB 36 0.024 1CYD-A nrPDB 36 0.027 5ILO-A nrPDB 36 0.028 3VPX-A nrPDB 36 0.030 2ISQ-A nrPDB 36 0.033 1E3W-A nrPDB 36 0.033 5Z1Z-A nrPDB 35 0.036 2ZJ1-A nrPDB 35 0.036 1ZFN-A nrPDB 35 0.038 3D3W-A nrPDB 35 0.043 4CUK-A nrPDB 35 0.046 3GRP-A nrPDB 35 0.051 1BW9-B nrPDB 35 0.051 3EMK-A nrPDB 35 0.053 6BII-A nrPDB 35 0.054 5D84-A nrPDB 35 0.055 5F8E-A nrPDB 35 0.056 2O23-A nrPDB 35 0.058 1V9L-A nrPDB 35 0.060 5JXW-A nrPDB 35 0.064 1DOD-A nrPDB 35 0.064 4XIJ-A nrPDB 35 0.066 1GPJ-A nrPDB 35 0.070 5UYY-A nrPDB 35 0.074 4E4T-A nrPDB 35 0.076 3C3P-A nrPDB 34 0.088 2B25-A nrPDB 34 0.10 6C55-A nrPDB 34 0.11 2HMT-A nrPDB 34 0.11 2VHY-A nrPDB 34 0.13 4K2X-A nrPDB 33 0.13 6BQ5-A nrPDB 33 0.14 5BUT-A nrPDB 33 0.14 4J90-A nrPDB 33 0.14 2YVG-A nrPDB 33 0.15 6DLL-A nrPDB 33 0.16 1DXY-A nrPDB 33 0.16 1ZFJ-A nrPDB 33 0.17 4A6N-B nrPDB 33 0.18 3FBT-A nrPDB 33 0.20 5FUB-A nrPDB 33 0.20 1XDW-A nrPDB 33 0.20 2A9F-A nrPDB 33 0.20 5VMT-A nrPDB 33 0.22 3G1U-A nrPDB 33 0.22 4COO-A nrPDB 33 0.23 5JJC-A nrPDB 33 0.23 4XGI-A nrPDB 33 0.23 1V8B-A nrPDB 33 0.26 1M54-A nrPDB 33 0.26 5MMS-A nrPDB 33 0.28 5U9P-A nrPDB 33 0.29 3HM2-A nrPDB 32 0.31 6ACF-A nrPDB 32 0.32 3X2F-A nrPDB 32 0.32 3PPI-A nrPDB 32 0.32 1VH3-A nrPDB 32 0.34 1JWB-B nrPDB 32 0.34 6APH-A nrPDB 32 0.35 3GDH-A nrPDB 32 0.37 3KTC-A nrPDB 32 0.38 5XW3-A nrPDB 32 0.38 3OND-A nrPDB 32 0.42 1KR5-A nrPDB 32 0.42 3EGI-A nrPDB 32 0.45 5UOG-A nrPDB 32 0.47 2EKL-A nrPDB 32 0.49 1J6U-A nrPDB 32 0.54 6MAT-A nrPDB 32 0.57 2YYZ-A nrPDB 32 0.58 2EEZ-A nrPDB 32 0.59 4EJ0-A nrPDB 32 0.59 3F9I-A nrPDB 32 0.59 3AOE-A nrPDB 32 0.60 6GBN-A nrPDB 32 0.64 4IZO-A nrPDB 32 0.64 4BUB-A nrPDB 32 0.64 3NJ4-A nrPDB 32 0.65 6DHM-A nrPDB 32 0.65 6CU3-A nrPDB 31 0.66 4K28-A nrPDB 31 0.66 1JG3-A nrPDB 31 0.69 6F3O-A nrPDB 31 0.71 2AS0-A nrPDB 31 0.73 3X43-A nrPDB 31 0.76 2BRY-A nrPDB 31 0.78 4TXK-A nrPDB 31 0.78 1QO8-A nrPDB 31 0.79 5IJZ-A nrPDB 31 0.87 5NMX-A nrPDB 31 0.90 5T5Q-A nrPDB 31 0.96 5TQV-A nrPDB 31 0.98 3BKW-A nrPDB 31 0.98 4RL6-A nrPDB 31 1.1 1DL5-A nrPDB 31 1.1 4V61-BD nrPDB 31 1.1 3LLV-A nrPDB 30 1.2 4FHN-X nrPDB 30 1.2 1CRW-G nrPDB 30 1.3 6J0Z-C nrPDB 30 1.3 4YRY-B nrPDB 30 1.5 3N58-A nrPDB 30 1.5 1O54-A nrPDB 30 1.6 6ABI-A nrPDB 30 1.6 1MV8-A nrPDB 30 1.7 3GDF-A nrPDB 30 1.7 1L1F-A nrPDB 30 1.7 3KYD-B nrPDB 30 1.9 3JTM-A nrPDB 30 1.9 3KYC-B nrPDB 30 2.0 3JTJ-A nrPDB 30 2.0 3HG7-A nrPDB 30 2.0 1HL3-A nrPDB 30 2.0 2YFH-A nrPDB 30 2.0 5MGZ-A nrPDB 30 2.1 3H9U-A nrPDB 30 2.3 4WJI-A nrPDB 30 2.3 3NNK-A nrPDB 30 2.3 2D1F-A nrPDB 30 2.4 3HDH-A nrPDB 29 2.5 3K8D-A nrPDB 29 2.6 5AOV-A nrPDB 29 2.6 5B37-A nrPDB 29 2.8 6HNS-A nrPDB 29 2.8 4PZE-A nrPDB 29 3.0 1F14-A nrPDB 29 3.1 4LRT-B nrPDB 29 3.2 4DIM-A nrPDB 29 3.2 3FEO-A nrPDB 29 3.3 3DC2-A nrPDB 29 3.4 5Y0R-A nrPDB 29 3.5 3GG9-A nrPDB 29 3.6 2JFH-A nrPDB 29 3.7 5M65-A nrPDB 29 3.8 3FG2-P nrPDB 29 3.8 2WWR-A nrPDB 29 3.9 3D64-A nrPDB 29 4.0 3UKH-A nrPDB 29 4.1 2YXL-A nrPDB 29 4.1 3M9X-A nrPDB 29 4.2 6GAW-AK nrPDB 28 4.3 4KUG-A nrPDB 28 4.3 4F86-A nrPDB 28 4.3 2YQ5-A nrPDB 28 4.3 3EBC-A nrPDB 28 4.4 3E45-A nrPDB 28 4.4 2W2L-A nrPDB 28 4.4 1QP8-A nrPDB 28 4.7 5JE5-A nrPDB 28 4.8 1VKF-A nrPDB 28 4.8 1YFM-A nrPDB 28 4.8 3AOE-E nrPDB 28 4.9 3JD5-K nrPDB 28 5.0 1LTH-T nrPDB 28 5.1 3OC4-A nrPDB 28 5.2 5GUP-m nrPDB 28 5.3 5JFC-L nrPDB 28 5.3 3A26-A nrPDB 28 5.3 5VJ7-A nrPDB 28 5.6 4PY5-A nrPDB 28 5.6 2EXX-A nrPDB 28 5.7 4PRK-A nrPDB 28 5.8 5AJ4-AK nrPDB 28 6.1 5EES-A nrPDB 28 6.2 4GBJ-A nrPDB 28 6.5 5D8N-A nrPDB 28 6.9 1FOH-A nrPDB 28 7.0 3VZS-A nrPDB 28 7.1 1DB3-A nrPDB 28 7.1 3OJO-A nrPDB 28 7.3 1URG-A nrPDB 28 7.3 3K8Z-A nrPDB 28 7.4 4XWI-A nrPDB 28 7.6 2W6I-D nrPDB 28 7.6 3RHA-A nrPDB 28 7.7 3H9E-O nrPDB 28 7.9 4OUR-B nrPDB 28 8.0 3TQV-A nrPDB 28 8.5 4X4J-A nrPDB 28 8.7 1VLM-A nrPDB 28 8.7 1EUZ-A nrPDB 28 9.0 5B1I-A nrPDB 27 9.5 4P4L-A nrPDB 27 9.6 5J46-A nrPDB 27 9.9 2G5C-A nrPDB 27 9.9 2B4Q-A nrPDB 27 10.0 >1PL8-A nrPDB Length = 356 Score = 469 bits (1206), Expect = e-132, Method: Composition-based stats. Identities = 355/356 (99%), Positives = 355/356 (99%) Query: 2 AAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI 61 AAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI Sbjct: 1 AAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI 60 Query: 62 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA 121 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA Sbjct: 61 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA 120 Query: 122 TPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA 181 TPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA Sbjct: 121 TPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA 180 Query: 182 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLG 241 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLG Sbjct: 181 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLG 240 Query: 242 CKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYC 301 CKPEVTIECTGAEASIQAGIYATRSGG LVLVGLGSEMTTVPLLHAAIREVDIKGVFRYC Sbjct: 241 CKPEVTIECTGAEASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYC 300 Query: 302 NTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP 357 NTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP Sbjct: 301 NTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP 356 >3QE3-A nrPDB Length = 355 Score = 446 bits (1148), Expect = e-126, Method: Composition-based stats. Identities = 311/355 (87%), Positives = 335/355 (94%), Gaps = 2/355 (0%) Query: 5 AKP--NNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIV 62 AKP NLSLVVHGPGDLRLENYPIPEPGPNEVLL+MHSVGICGSDVHYW++GRIG+F+V Sbjct: 1 AKPAAENLSLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVV 60 Query: 63 KKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCAT 122 KKPMVLGHEASGTV KVGS V+HL+PGDRVAI+PGAPR+ DEFCK+GRYNLSP+IFFCAT Sbjct: 61 KKPMVLGHEASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCAT 120 Query: 123 PPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAG 182 PPDDGNLCRFYKHNA FCYKLPDNVTFEEGALIEPLSVGIHACRR GVTLG+KVLVCGAG Sbjct: 121 PPDDGNLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAG 180 Query: 183 PIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGC 242 PIG+V LL AKAMGAAQVVVTDLSA+RLSKAKE+GAD +L+IS ESP+EIA+KVEG LG Sbjct: 181 PIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVEGLLGS 240 Query: 243 KPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCN 302 KPEVTIECTG E SIQAGIYAT SGG LVLVGLGSEMT+VPL+HAA REVDIKGVFRYCN Sbjct: 241 KPEVTIECTGVETSIQAGIYATHSGGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRYCN 300 Query: 303 TWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP 357 TWP+AISMLASKSVNVKPLVTHRFPLEKALEAFET KKGLGLK+M+KCDPSDQNP Sbjct: 301 TWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGLKVMIKCDPSDQNP 355 >1E3J-A nrPDB Length = 352 Score = 369 bits (947), Expect = e-102, Method: Composition-based stats. Identities = 207/347 (59%), Positives = 255/347 (73%), Gaps = 5/347 (1%) Query: 8 NNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMV 67 +NLS V++ DLRLE PIPEP +EVLL+M VGICGSDVHY+E+GRI +FIVK PMV Sbjct: 4 DNLSAVLYKQNDLRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMV 63 Query: 68 LGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDG 127 +GHEASGTV KVG +VKHLK GDRVA+EPG P +FCK G+YNL P + FCATPPDDG Sbjct: 64 IGHEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTFCATPPDDG 123 Query: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMV 187 NL R+Y H A FC+KLPDNV+ EEGAL+EPLSVG+HACRR GV LG VLV GAGPIG+V Sbjct: 124 NLARYYVHAADFCHKLPDNVSLEEGALLEPLSVGVHACRRAGVQLGTTVLVIGAGPIGLV 183 Query: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADL--VLQISKESPQEIARKVEGQLGCKPE 245 ++L AKA GA VV T S RL AK GAD+ V+ +KE I ++ +G P Sbjct: 184 SVLAAKAYGAF-VVCTARSPRRLEVAKNCGADVTLVVDPAKEEESSIIERIRSAIGDLPN 242 Query: 246 VTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWP 305 VTI+C+G E I GI TR+GG L+LVG+GS+M TVPL++A RE+DIK VFRYCN +P Sbjct: 243 VTIDCSGNEKCITIGINITRTGGTLMLVGMGSQMVTVPLVNACAREIDIKSVFRYCNDYP 302 Query: 306 VAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL--GLKIMLKC 350 +A+ M+AS NVK LVTH F LE+ ++AFE +K +K+M+ C Sbjct: 303 IALEMVASGRCNVKQLVTHSFKLEQTVDAFEAARKKADNTIKVMISC 349 >2DFV-A nrPDB Length = 347 Score = 316 bits (811), Expect = 8e-87, Method: Composition-based stats. Identities = 96/332 (28%), Positives = 168/332 (50%), Gaps = 8/332 (2%) Query: 21 RLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVG 80 L +P+PGP EVL+++ + ICG+D+H +E+ +K P ++GHE +G V ++G Sbjct: 17 ELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIG 76 Query: 81 SSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFC 140 V+ ++ GD V++E C+ G+Y++ + DG + A Sbjct: 77 PGVEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGVDT-DGVFAEYAVVPAQNI 135 Query: 141 YKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQV 200 +K P ++ E L EPL + G ++ G VL+ GAGP+G++ + VAKA GA V Sbjct: 136 WKNPKSIPPEYATLQEPLGNAVDTVLAGPIS-GKSVLITGAGPLGLLGIAVAKASGAYPV 194 Query: 201 VVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAG 260 +V++ S R AK++GAD V+ +E + + G +V +E +GA +++ G Sbjct: 195 IVSEPSDFRRELAKKVGADYVINPFEEDVVKEVMDITD--GNGVDVFLEFSGAPKALEQG 252 Query: 261 IYATRSGGNLVLVGLGSEMTTVPLLHAAI-REVDIKGVF--RYCNTWPVAISMLASKSVN 317 + A G + L+GL T+ + I + + I G+ TW +L S +N Sbjct: 253 LQAVTPAGRVSLLGLYPGKVTIDFNNLIIFKALTIYGITGRHLWETWYTVSRLLQSGKLN 312 Query: 318 VKPLVTHRFP-LEKALEAFETFKKGLGLKIML 348 + P++TH++ +K EAFE + G K++ Sbjct: 313 LDPIITHKYKGFDKYEEAFELMRAGKTGKVVF 344 >3GFB-A nrPDB Length = 350 Score = 315 bits (806), Expect = 2e-86, Method: Composition-based stats. Identities = 100/332 (30%), Positives = 169/332 (50%), Gaps = 8/332 (2%) Query: 21 RLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVG 80 L +P+PGP EVL+++ + ICG+D+H +E+ +K P ++GHE +G V +VG Sbjct: 18 ELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEVG 77 Query: 81 SSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFC 140 V+ L+ GD +++E CK RY++ + DG + A Sbjct: 78 PGVEDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKIFGV-DMDGVFAHYAIVPAKNA 136 Query: 141 YKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQV 200 +K P ++ E AL EPL + G G L+ GAGP+G++ + VAKA GA V Sbjct: 137 WKNPKDMPPEYAALQEPLGNAVDTV-LAGPIAGRSTLITGAGPLGLLGIAVAKASGAYPV 195 Query: 201 VVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAG 260 +V++ S R AK++GAD V+ +E P + + G EV +E +GA +++ G Sbjct: 196 IVSEPSEFRRKLAKKVGADYVVNPFEEDPVKFVMDITD--GAGVEVFLEFSGAPKALEQG 253 Query: 261 IYATRSGGNLVLVGLGSEMTTVPLLHAAI-REVDIKGVF--RYCNTWPVAISMLASKSVN 317 + A GG + L+GL T+ + I + +++ G+ TW S++ S +N Sbjct: 254 LKAVTPGGRVSLLGLFPREVTIDFNNLIIFKALEVHGITGRHLWETWYTVSSLIQSGKLN 313 Query: 318 VKPLVTHRFP-LEKALEAFETFKKGLGLKIML 348 + P++TH++ +K EAFE + G K++ Sbjct: 314 LDPIITHKYKGFDKFEEAFELMRAGKTGKVVF 345 >5VM2-A nrPDB Length = 347 Score = 310 bits (793), Expect = 8e-85, Method: Composition-based stats. Identities = 127/332 (38%), Positives = 189/332 (56%), Gaps = 9/332 (2%) Query: 9 NLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKP--- 65 N ++ PG +++ + IP P +EVL+++ VGICGSDVH +E G K P Sbjct: 3 NSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESG--PFIPPKDPNQE 60 Query: 66 MVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD 125 + LGHE +GTV VGS V+ KPGDRV IEPG P + +C G+YN+ P + F AT P+ Sbjct: 61 IGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPN 120 Query: 126 D-GNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPI 184 G L + H +F YKLPDN+ EG L+EP +VG+HA V G K+++ GAG I Sbjct: 121 YRGALTHYLCHPESFTYKLPDNMDTMEGTLVEPAAVGMHAAMLADVKPGKKIIILGAGCI 180 Query: 185 GMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 G++TL K +GA ++ V D+ RL+ A+++GA +V+ +KE IAR + Sbjct: 181 GLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAKEDT--IARCQQFTEDMGA 238 Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTW 304 ++ E G+ +++ Y GG +++VG + + L REV I+ VFRY N + Sbjct: 239 DIVFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGASAINFLKIN-REVTIQTVFRYANRY 297 Query: 305 PVAISMLASKSVNVKPLVTHRFPLEKALEAFE 336 PV I ++S +VK +VTH + +AFE Sbjct: 298 PVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >3M6I-A nrPDB Length = 363 Score = 307 bits (787), Expect = 4e-84, Method: Composition-based stats. Identities = 153/347 (44%), Positives = 218/347 (62%), Gaps = 11/347 (3%) Query: 1 MAAAAKPNNLSLVVHGPGDLRLENYPIP--------EPGPNEVLLRMHSVGICGSDVHYW 52 MA++A N+ + + DL + E EV + + S GICGSDVH+W Sbjct: 1 MASSASKTNIGVFTNPQHDLWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFW 60 Query: 53 EYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYN 112 ++G IG IV+ VLGHE++G V V SVK +K GDRVAIEP E C GRYN Sbjct: 61 KHGCIGPMIVECDHVLGHESAGEVIAVHPSVKSIKVGDRVAIEPQVICNACEPCLTGRYN 120 Query: 113 LSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTL 172 + F +TPP G L R+ H A +C+K+ N+++E GA++EPLSV + +R GV L Sbjct: 121 GCERVDFLSTPPVPGLLRRYVNHPAVWCHKI-GNMSYENGAMLEPLSVALAGLQRAGVRL 179 Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV-LQISKESPQE 231 G VL+CGAGPIG++T+L AKA GA +V+TD+ RL AKEI ++V ++ + S +E Sbjct: 180 GDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEICPEVVTHKVERLSAEE 239 Query: 232 IARKVEGQLGC-KPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIR 290 A+K+ G +P V +ECTG E+SI A I+A + GG + ++G+G +P + A++R Sbjct: 240 SAKKIVESFGGIEPAVALECTGVESSIAAAIWAVKFGGKVFVIGVGKNEIQIPFMRASVR 299 Query: 291 EVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFET 337 EVD++ +RYCNTWP AI ++ + V++ LVTHRFPLE AL+AFET Sbjct: 300 EVDLQFQYRYCNTWPRAIRLVENGLVDLTRLVTHRFPLEDALKAFET 346 >2DQ4-A nrPDB Length = 343 Score = 306 bits (784), Expect = 1e-83, Method: Composition-based stats. Identities = 108/339 (31%), Positives = 172/339 (50%), Gaps = 10/339 (2%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVE 77 L L + P+PEPGP E+L+R+ + ICG+D+H W++ ++ P+V GHE SG VE Sbjct: 11 EGLTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPLVTGHEFSGVVE 70 Query: 78 KVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNA 137 VG V+ + GD V++E C+ G Y++ + DG + A Sbjct: 71 AVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQILGV-DRDGGFAEYVVVPA 129 Query: 138 AFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGA 197 + P ++ FE A++EP +H G G VL+ GAGPIG++ +V +A GA Sbjct: 130 ENAWVNPKDLPFEVAAILEPFGNAVHTVYAGSGVSGKSVLITGAGPIGLMAAMVVRASGA 189 Query: 198 AQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASI 257 ++V+D + RL+ A+ AD ++ +E E+ R+V G EV +E +G EA+I Sbjct: 190 GPILVSDPNPYRLAFARPY-ADRLVNPLEEDLLEVVRRVT---GSGVEVLLEFSGNEAAI 245 Query: 258 QAGIYATRSGGNLVLVGLGSEMTTVPL-LHAAIREVDIKG--VFRYCNTWPVAISMLASK 314 G+ A GG ++G+ S+ L +R + G R TW +++ S Sbjct: 246 HQGLMALIPGGEARILGIPSDPIRFDLAGELVMRGITAFGIAGRRLWQTWMQGTALVYSG 305 Query: 315 SVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPS 353 V++ PL+THR PL + EAF G +K++L DP Sbjct: 306 RVDLSPLLTHRLPLSRYREAFGLLASGQAVKVIL--DPK 342 >1HSO-A nrPDB Length = 374 Score = 304 bits (779), Expect = 3e-83, Method: Composition-based stats. Identities = 91/359 (25%), Positives = 148/359 (41%), Gaps = 37/359 (10%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 +E + P +EV ++M +VGICG+D H G + P++LGHEA+G VE V Sbjct: 21 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILGHEAAGIVESV 76 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS---------------PSIFFCATPP 124 G V +KPGD+V CK N S F C P Sbjct: 77 GEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKP 136 Query: 125 DD-----GNLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGI-HACRRGGVTLGHKVL 177 ++ + K+ E+ LI S G A VT G Sbjct: 137 IHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCA 196 Query: 178 VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQI--SKESPQEIARK 235 V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + K+ QE+ ++ Sbjct: 197 VFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE 256 Query: 236 VEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSE-----MTTVPLLHAAI 289 + + + E G ++ A + G V+VG+ + M + LL Sbjct: 257 MTDG---GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRT 313 Query: 290 REVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 + I G F+ P ++ +K ++ L+TH P EK E F+ G ++ +L Sbjct: 314 WKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTIL 372 >5KIA-A nrPDB Length = 351 Score = 299 bits (766), Expect = 1e-81, Method: Composition-based stats. Identities = 93/341 (27%), Positives = 170/341 (49%), Gaps = 8/341 (2%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 L+ + GPG L L PE G N+VL+++ ICG+D+H W++ + PM +G Sbjct: 12 LAKLERGPG-LTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVG 70 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNL 129 HE G + ++G V+ GDRV+ E C+ GR +L + +G Sbjct: 71 HEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVN-REGAF 129 Query: 130 CRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTL 189 + A +K+P ++ + A+ +P H + G VL+ GAGPIG++ + Sbjct: 130 AEYLAIPAFNAFKIPPEISDDLAAIFDPFGNATHTALSFNLV-GEDVLITGAGPIGVMAV 188 Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249 +AK +GA VV+TD++ RL A+ +GA + +S+ES +++ + G +V +E Sbjct: 189 AIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRESLRDVMADLHMTEG--FDVGLE 246 Query: 250 CTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFR--YCNTWPVA 307 +G ++ + + + GG + L+G+ T + + ++IKG++ TW Sbjct: 247 MSGVPSAFTSLLESMNHGGKVALLGIPPAQTAIDWNQVIFKGLEIKGIYGREMFETWYKM 306 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 ++ML S +++ P++THRF ++ + F G K++L Sbjct: 307 VAMLQSG-LDLSPIITHRFAVDDYEKGFAAMLSGESGKVIL 346 >1HSZ-A nrPDB Length = 374 Score = 299 bits (765), Expect = 1e-81, Method: Composition-based stats. Identities = 88/369 (23%), Positives = 149/369 (40%), Gaps = 37/369 (10%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 +++ +E+ + P EV ++M +VGIC +D H GN + P++LG Sbjct: 11 AAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVS----GNLVTPLPVILG 66 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS--------------- 114 HEA+G VE VG V +KPGD+V CK N Sbjct: 67 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 126 Query: 115 PSIFFCATPPDD-----GNLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGI-HACRR 167 F C P ++ + K+ E+ LI S G A Sbjct: 127 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 186 Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQI--S 225 VT G V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Sbjct: 187 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 246 Query: 226 KESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSE-----M 279 K+ QE+ +++ + + E G ++ A + G V+VG+ + Sbjct: 247 KKPIQEVLKEMTDG---GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSI 303 Query: 280 TTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFK 339 + LL + + G F+ P ++ +K ++ L+TH P EK E F+ Sbjct: 304 NPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLH 363 Query: 340 KGLGLKIML 348 G ++ +L Sbjct: 364 SGKSIRTVL 372 >1U3W-A nrPDB Length = 374 Score = 299 bits (765), Expect = 1e-81, Method: Composition-based stats. Identities = 88/359 (24%), Positives = 150/359 (41%), Gaps = 37/359 (10%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 +E + P +EV ++M + GIC SD H GN + P++LGHEA+G VE V Sbjct: 21 FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS----GNLVTPLPVILGHEAAGIVESV 76 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS---------------PSIFFCATPP 124 G V +KPGD+V CK N F C+ P Sbjct: 77 GEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP 136 Query: 125 DD-----GNLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGI-HACRRGGVTLGHKVL 177 ++ + K+ E+ LI S G A + VT G Sbjct: 137 IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCA 196 Query: 178 VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQI--SKESPQEIARK 235 V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + K+ QE+ ++ Sbjct: 197 VFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE 256 Query: 236 VEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSE-----MTTVPLLHAAI 289 + + + E G ++ A + G V+VG+ + + + LL Sbjct: 257 MTDG---GVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRT 313 Query: 290 REVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 + I G F+ + P ++ +K ++ L+T+ P EK E F+ + G ++ +L Sbjct: 314 WKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFDLLRSGKSIRTVL 372 >1EE2-A nrPDB Length = 373 Score = 291 bits (745), Expect = 3e-79, Method: Composition-based stats. Identities = 86/366 (23%), Positives = 151/366 (41%), Gaps = 32/366 (8%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 +++ +E + P +EV ++M + GIC SD H G + P++ G Sbjct: 11 AAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVS----GTLVAPLPVIAG 66 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS--------------P 115 HEA+G VE +G V ++PGD+V CK NL Sbjct: 67 HEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKNLSMPRGTMQDGT 126 Query: 116 SIFFCATPPDD-----GNLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGI-HACRRG 168 S F C P ++ + K+ E+ L+ S G A + Sbjct: 127 SRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGYGSAVKVA 186 Query: 169 GVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKES 228 VT G V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + ++ Sbjct: 187 KVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVN-PQDY 245 Query: 229 PQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSE-----MTTV 282 + I + + + E G ++ A + + G V+VG+ + M + Sbjct: 246 KKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQNLSMNPM 305 Query: 283 PLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 LL + I G F+ ++ P ++ +K + PL+TH P EK E F+ + G Sbjct: 306 LLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGK 365 Query: 343 GLKIML 348 ++ +L Sbjct: 366 SIRTIL 371 >3PII-A nrPDB Length = 339 Score = 288 bits (736), Expect = 3e-78, Method: Composition-based stats. Identities = 98/347 (28%), Positives = 155/347 (44%), Gaps = 13/347 (3%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 ++V L+++ P EVL+R+ + G+C +D+H K P++ G Sbjct: 3 AAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDW--PVKPKLPLIPG 60 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEP-GAPRENDEFCKMGRYNLSPSIFFCATPPDDGN 128 HE G VE+VG V HLK GDRV I + + ++C G+ L DG Sbjct: 61 HEGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLCEHQKNAG-YSVDGG 119 Query: 129 LCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGMV 187 + + A + K+PDN++FEE A I V + A + G G V + G G G V Sbjct: 120 YAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTYKALKVTGAKPGEWVAIYGIGGFGHV 179 Query: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVT 247 + AKAMG VV D+ +L AKE+GADLV+ KE + ++ G Sbjct: 180 AVQYAKAMGL-NVVAVDIGDEKLELAKELGADLVVNPLKEDAAKFMKEKVG----GVHAA 234 Query: 248 IECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVA 307 + ++ + Q+ + R GG VLVGL E +P+ + + I G + Sbjct: 235 VVTAVSKPAFQSAYNSIRRGGACVLVGLPPEEMPIPIFDTVLNGIKIIGSIVGTRK-DLQ 293 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL-GLKIMLKCDPS 353 ++ + VK ++ PLEK E F+ KG +++L + Sbjct: 294 EALQFAAEGKVKTII-EVQPLEKINEVFDRMLKGQINGRVVLTLEDK 339 >3COS-A nrPDB Length = 381 Score = 285 bits (730), Expect = 2e-77, Method: Composition-based stats. Identities = 78/371 (21%), Positives = 152/371 (40%), Gaps = 36/371 (9%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 ++ L +E + P +EV +++ + +C +D + G + P+++G Sbjct: 13 AAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVG 69 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDG-- 127 HEA+G VE +G V ++KPGD+V +FC NL I +P D Sbjct: 70 HEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 129 Query: 128 ----------------------NLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGIHA 164 ++ + K+ D+ E L+ S G A Sbjct: 130 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 189 Query: 165 C-RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQ 223 VT G V G G +G+ ++ KA GA++++ D+++ + KAK +GA L Sbjct: 190 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 249 Query: 224 ISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSEMTTV 282 ++ + I + + ++C G +++A + T +G G+ +G+ + + Sbjct: 250 -PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 308 Query: 283 PLLH-----AAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFET 337 + G ++ ++ P ++ +K N+ LVTH P +K EAF+ Sbjct: 309 TVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDL 368 Query: 338 FKKGLGLKIML 348 +G ++ +L Sbjct: 369 MNQGKSIRTIL 379 >1E3E-A nrPDB Length = 376 Score = 284 bits (728), Expect = 3e-77, Method: Composition-based stats. Identities = 79/369 (21%), Positives = 150/369 (40%), Gaps = 35/369 (9%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 ++ L +E + P EV +++ + +C +D++ + + F P+VLG Sbjct: 11 AAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKALF----PVVLG 66 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDG-- 127 HE +G VE VG V + KPGD+V + + C NL + P D Sbjct: 67 HECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYPTIDQEL 126 Query: 128 ----------------------NLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGIHA 164 + ++ + A ++ D E LI S G A Sbjct: 127 MEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFSSGYGA 186 Query: 165 C-RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQ 223 VT G V G G +G+ ++ K GA++++ D++ + KAK +GA L Sbjct: 187 AINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALGATDCLN 246 Query: 224 ISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSEMTTV 282 + + + + + +++C G +++A + T G G+ +VG + T+ Sbjct: 247 PRELD-KPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKVDEMTI 305 Query: 283 PLLHAAIR---EVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFK 339 P + + G ++ ++ P +S +K ++ LVTH P E +A + K Sbjct: 306 PTVDVILGRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESINDAIDLMK 365 Query: 340 KGLGLKIML 348 +G ++ +L Sbjct: 366 EGKSIRTIL 374 >2EER-A nrPDB Length = 347 Score = 282 bits (721), Expect = 2e-76, Method: Composition-based stats. Identities = 97/339 (28%), Positives = 154/339 (45%), Gaps = 15/339 (4%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI------VKKPMVLGHEAS 73 L+LE+ PIP+P ++VL+++ + G+C SDVH + GR GN VK P+ LGHE + Sbjct: 13 LKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQ-GRFGNLRIVEDLGVKLPVTLGHEIA 71 Query: 74 GTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFY 133 G +E+VG V GD VA+ P N +C++G +L S + DG + Sbjct: 72 GRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLCDSPRWLGINY-DGAYAEYV 130 Query: 134 KHNA-AFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA-GPIGMVTLLV 191 + YKL E L A R+ + ++V GA G +G + + + Sbjct: 131 LVPHYKYLYKLRRLSAVEAAPLTCSGVTTYRAVRKASLDPSKTLVVIGAGGGLGTMAIQI 190 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECT 251 AKA+ A ++ D+ L AK GAD V+ S + P R++ G + I+ Sbjct: 191 AKAVSGATIIGVDVREEALEAAKRAGADYVINASSQDPVSEIRRIT--QGKGADAVIDLN 248 Query: 252 GAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISML 311 +E ++ Y G V+VGL + EV G + + I L Sbjct: 249 NSEKTLSIYPYVLAKQGKYVMVGLFGADLKYHAPLITLNEVQFIGSLVGNQSDFLGIMSL 308 Query: 312 ASKSVNVKPLVTHRFPLEKALEAFETFK--KGLGLKIML 348 A VKP+VT LE+A EA + + K +G ++++ Sbjct: 309 AEAG-KVKPMVTKTMKLEEANEAIDNLENFKAVGRQVLV 346 >4DLA-A nrPDB Length = 396 Score = 281 bits (718), Expect = 4e-76, Method: Composition-based stats. Identities = 84/370 (22%), Positives = 147/370 (39%), Gaps = 33/370 (8%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 ++ L +E+ + P EV +++ +C +D + W P VLG Sbjct: 29 AAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEGL---FPCVLG 85 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF---FCATPPDD 126 HEA+G VE VG V ++PGD V A +FCK G+ NL + +D Sbjct: 86 HEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAATGVGVMMND 145 Query: 127 ------------------GNLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGIHAC-R 166 ++ + K+ E+ L+ + G+ A Sbjct: 146 RKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPTGLGAVWN 205 Query: 167 RGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK 226 V G V V G G +G+ AKA GA++++ D+ + + +AK G + K Sbjct: 206 TAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVTEFIN-PK 264 Query: 227 ESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL---GSEMTTV 282 E Q I + + + + EC G + +++ + G G V+VG+ G E++T Sbjct: 265 EHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASGQEISTR 324 Query: 283 P--LLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKK 340 P L+ + + G F+ + P + K + V +TH L +AF+ Sbjct: 325 PFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKAFDLMHD 384 Query: 341 GLGLKIMLKC 350 G L+++L Sbjct: 385 GDCLRVVLDM 394 >4JJI-A nrPDB Length = 378 Score = 279 bits (715), Expect = 9e-76, Method: Composition-based stats. Identities = 78/368 (21%), Positives = 146/368 (39%), Gaps = 33/368 (8%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 ++ L +E+ + P EV +++ +C +D + W P +LG Sbjct: 11 AAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEGL---FPCILG 67 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF---FCATPPDD 126 HEA+G VE VG V ++ GD V A +FCK G+ NL + +D Sbjct: 68 HEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATGVGIMMND 127 Query: 127 ------------------GNLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGIHAC-R 166 ++ + K+ ++ L+ + G+ A Sbjct: 128 RKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPTGLGAVWN 187 Query: 167 RGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK 226 V G V + G G +G+ AK GA++++ D+ + + AK+ G + + K Sbjct: 188 TAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVNEFVN-PK 246 Query: 227 ESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL---GSEMTTV 282 + + I + + + EC G + ++A + G G V+VG+ G E++T Sbjct: 247 DHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASGQEISTR 306 Query: 283 P--LLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKK 340 P L+ + + G F+ P + +K + V +TH L + +AF+ + Sbjct: 307 PFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKAFDLLHE 366 Query: 341 GLGLKIML 348 G L+ +L Sbjct: 367 GTCLRCVL 374 >4OH1-A nrPDB Length = 351 Score = 277 bits (709), Expect = 4e-75, Method: Composition-based stats. Identities = 84/342 (24%), Positives = 155/342 (45%), Gaps = 18/342 (5%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYG---RIGNFIVKKPMVLGHEASG 74 G + + P+PEP E+ +++ ICGSD H PM GHE SG Sbjct: 19 GTVDMMEAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSG 78 Query: 75 TVEKVGSSVK--HLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRF 132 ++KVGS+ + K G +V E C+ G+ NL ++ + + Sbjct: 79 VIDKVGSTAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSNMGYRMN-----GFSEY 133 Query: 133 YKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVA 192 ++ + + +PD+ ++ AL+EPL+V + + + ++ G V + GAG +GM+ + +A Sbjct: 134 AVYHMSQIFPIPDDADLKDYALVEPLTVALSSAEQAKISYGKSVAIMGAGGLGMMLVQLA 193 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTG 252 + GA+ + V D+ +L A E GAD L ++E E A ++ G + + +E TG Sbjct: 194 RLAGASTITVFDIVPEKLELALENGADYALNSAEEGVAERAIELA---GGRYDCVLEGTG 250 Query: 253 AEASIQAGIYATRSGGNLVLVGLGSEMTTVPLL---HAAIREVDIKGVFRYCNTWPVAIS 309 A A+ + G+ G+ V + + +P+ + I G+ + +P +I Sbjct: 251 ATAAAKLGLQLLARDGDAVYFAMYGKDPILPVNLQSDLYWDQKHIHGMIQGAWQFPKSIR 310 Query: 310 MLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCD 351 M+ ++ ++ L +AFE KI++K D Sbjct: 311 MI--PRMDFSKIIQKEHTLTNYKQAFEDLYSKKYAKIVIKMD 350 >1D1T-A nrPDB Length = 373 Score = 276 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 81/366 (22%), Positives = 148/366 (40%), Gaps = 32/366 (8%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 +++ +E + P EV +++ + GIC +D H + G + K P+++G Sbjct: 11 AAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIK----GTMVSKFPVIVG 66 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS--------------P 115 HEA+G VE +G V +KPGD+V C+ NL Sbjct: 67 HEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 126 Query: 116 SIFFCATPP-----DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGIHA-CRRG 168 + F C P + + + + K+ D E+ LI S G A + G Sbjct: 127 TRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 186 Query: 169 GVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKES 228 V G +V G G +G+ ++ K+ GA++++ DL+ + KA +GA + K+S Sbjct: 187 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI-SPKDS 245 Query: 229 PQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSEMTTVP---- 283 + I+ + G T E G ++ + + G V+VG+ + Sbjct: 246 TKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM 305 Query: 284 -LLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 L + + G + + P ++ +K ++ L+TH P +K E FE G Sbjct: 306 LLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ 365 Query: 343 GLKIML 348 ++ +L Sbjct: 366 SIRTVL 371 >1MC5-A nrPDB Length = 374 Score = 274 bits (702), Expect = 3e-74, Method: Composition-based stats. Identities = 77/377 (20%), Positives = 140/377 (37%), Gaps = 32/377 (8%) Query: 1 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF 60 MA ++ L +E + P +EV +++ + +C +D + + Sbjct: 1 MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSG---ADP 57 Query: 61 IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFC 120 P++LGHE +G VE VG V LK GD V +FC + NL I Sbjct: 58 EGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVT 117 Query: 121 ATPP--DDGN------------------LCRFYKHNAAFCYKLPDNVTFEEGALIEP-LS 159 DG + K+ ++ L+ +S Sbjct: 118 QGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGIS 177 Query: 160 VGIHA-CRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGA 218 G A + G V G G +G+ ++ K GA++++ D++ + ++AKE GA Sbjct: 178 TGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGA 237 Query: 219 DLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG----GNLVLVG 274 + ++ + I + + + EC G ++A + A G + + Sbjct: 238 TECIN-PQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAA 296 Query: 275 LGSEMTTVPLLHAAIREV--DIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKAL 332 G E+ T P R G ++ + P +S SK + V VTH ++ Sbjct: 297 SGEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEIN 356 Query: 333 EAFETFKKGLGLKIMLK 349 +AFE G ++ ++K Sbjct: 357 KAFELMHSGKSIRTVVK 373 >4ILK-A nrPDB Length = 359 Score = 273 bits (697), Expect = 1e-73, Method: Composition-based stats. Identities = 96/342 (28%), Positives = 155/342 (45%), Gaps = 11/342 (3%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 S+++ P L + IP P EV +++ GICGSD H + R N K P V+G Sbjct: 22 KSILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIY---RGHNPFAKYPRVIG 78 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNL 129 HE G ++ VG V+ + G+RVA++P + C +G+ N+ ++ DG Sbjct: 79 HEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGVH-ADGGF 137 Query: 130 CRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTL 189 + A +K+P+ V + +IEP ++ + G T VLV GAGPIG+ + Sbjct: 138 SEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTENDTVLVYGAGPIGLTIV 197 Query: 190 LVAK-AMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248 V K V+V D RL KAKE GAD + S+ E + G KP + I Sbjct: 198 QVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPLGESFAE----KGIKPTLII 253 Query: 249 ECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAI 308 + + ++ + +VL+G SE + V +E+ I N +PV I Sbjct: 254 DAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKELSIFSSRLNANKFPVVI 313 Query: 309 SMLASKSVNVKPLVTHRFPLEKALEAFETFK--KGLGLKIML 348 L+ + + L+TH F + +A F+ + K++L Sbjct: 314 DWLSKGLIKPEKLITHTFDFQHVADAISLFELDQKHCCKVLL 355 >1CDO-A nrPDB Length = 374 Score = 273 bits (697), Expect = 1e-73, Method: Composition-based stats. Identities = 78/367 (21%), Positives = 148/367 (40%), Gaps = 31/367 (8%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 ++ L +E + P NE+ +++ + G+C +D+++ G+ + P+VLG Sbjct: 11 AAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKD---GFPVVLG 67 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP----- 124 HE +G VE VG V +PG++V + FC+ + N + +P Sbjct: 68 HEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANESPDVMSPK 127 Query: 125 ---------------DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGIHA-CRR 167 ++ N K+ + + L+ +S G A Sbjct: 128 ETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTGFGAAVNT 187 Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKE 227 V G V G G +G+ ++ + GA +++ DL+ + KAK GA + + Sbjct: 188 AKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATDFVN-PND 246 Query: 228 SPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGS--EMTTVPL 284 + I++ + + ++EC G ++ + + G G VLVG ++ T P+ Sbjct: 247 HSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWTDLHDVATRPI 306 Query: 285 LHAAIREV--DIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 A R + G F+ + P + K V + +THR PLE +A + K G Sbjct: 307 QLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAIDLMKHGK 366 Query: 343 GLKIMLK 349 ++ +L Sbjct: 367 CIRTVLS 373 >1LLU-A nrPDB Length = 342 Score = 272 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 89/345 (25%), Positives = 142/345 (41%), Gaps = 14/345 (4%) Query: 10 LSLVVHGPGD-LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVL 68 + VVH G LR+E +P PGP +VL+++ + G+C +D+H E P + Sbjct: 8 KAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDW--PVKPPLPFIP 65 Query: 69 GHEASGTVEKVGSSVKHLKPGDRVAIEP-GAPRENDEFCKMGRYNLSPSIFFCATPPDDG 127 GHE G V VGS V +K GDRV I E C G L S + G Sbjct: 66 GHEGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQNTGYSVN-G 124 Query: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGM 186 + + + LP NV F E A I V ++ ++ G V + G G +G Sbjct: 125 GYAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVYKGLKQTNARPGQWVAISGIGGLGH 184 Query: 187 VTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEV 246 V + A+AMG V D+ +L A+++GA L + +E P E ++ G Sbjct: 185 VAVQYARAMGLH-VAAIDIDDAKLELARKLGASLTVNARQEDPVEAIQRDIG----GAHG 239 Query: 247 TIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPV 306 + + ++ I R GG + LVGL P+ ++ + I G Sbjct: 240 VLVTAVSNSAFGQAIGMARRGGTIALVGLPPGDFPTPIFDVVLKGLHIAGSIVGTRADLQ 299 Query: 307 AISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL-GLKIMLKC 350 A + + VK + H L+ + + + G +I+L+ Sbjct: 300 EALDFAGEGL-VKATI-HPGKLDDINQILDQMRAGQIEGRIVLEM 342 >4EJ6-A nrPDB Length = 370 Score = 270 bits (690), Expect = 8e-73, Method: Composition-based stats. Identities = 86/341 (25%), Positives = 161/341 (47%), Gaps = 7/341 (2%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 ++ + G++ + N IPEPGP+++L+++ + GICG+D H G F P+ LG Sbjct: 25 KAVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLH----GEFPSTPPVTLG 80 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNL 129 HE G V + GS+V+ + PG R+ +P C+ GR NL ++ DG Sbjct: 81 HEFCGIVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLRAIGIH-RDGGF 139 Query: 130 CRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTL 189 + +++P + GA EPL+ +H G+ G V + G G IG++T+ Sbjct: 140 AEYVLVPRKQAFEIPLTLDPVHGAFCEPLACCLHGVDLSGIKAGSTVAILGGGVIGLLTV 199 Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249 +A+ GA V+++ AT+ A+E+GA + S E G + +V IE Sbjct: 200 QLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEAIAGPVGLVPGGVDVVIE 259 Query: 250 CTGAEASIQAGIYATRSGGNLVLVGL--GSEMTTVPLLHAAIREVDIKGVFRYCNTWPVA 307 C G +++ ++GG +V++G+ E + RE+ + G F A Sbjct: 260 CAGVAETVKQSTRLAKAGGTVVILGVLPQGEKVEIEPFDILFRELRVLGSFINPFVHRRA 319 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 ++A+ ++ + +++ R L++A + +K+++ Sbjct: 320 ADLVATGAIEIDRMISRRISLDEAPDVISNPAAAGEVKVLV 360 >4Z6K-A nrPDB Length = 346 Score = 269 bits (687), Expect = 2e-72, Method: Composition-based stats. Identities = 86/338 (25%), Positives = 145/338 (42%), Gaps = 17/338 (5%) Query: 10 LSLVVHGPGD-LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PM 66 + V+H G L++E IP PG E++++M + G+C +D+H E G++ VK P Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVE----GDWPVKPSPPF 57 Query: 67 VLGHEASGTVEKVGSSVKHLKPGDRVAIEP-GAPRENDEFCKMGRYNLSPSIFFCATPPD 125 + GHE G + VG V H+K GDRV + + + C G L S + Sbjct: 58 IPGHEGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQNSGYSVN 117 Query: 126 DGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPI 184 G+ + NA + +P++V E A + V ++ + G V++ G G + Sbjct: 118 -GSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVYKGLKMTDTKPGDWVVISGIGGL 176 Query: 185 GMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 G + + A AMG V D+ +L+ AK++GA + + P E +K G Sbjct: 177 GHMAVQYAIAMGL-NVAAVDIDDDKLAFAKKLGAKVTVNAKNTDPAEYLQKEIG----GA 231 Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTW 304 + + + + R GG LV GL V + + + I+G Sbjct: 232 HGALVTAVSAKAFDQALSMLRRGGTLVCNGLPPGDFPVSIFDTVLNGITIRGSIVGT-RL 290 Query: 305 PVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 + S+ + + VK VT PLE + FE ++G Sbjct: 291 DLQESLDMAAAGKVKATVTAE-PLENINDIFERMRQGK 327 >4RQU-A nrPDB Length = 375 Score = 267 bits (682), Expect = 6e-72, Method: Composition-based stats. Identities = 73/370 (19%), Positives = 141/370 (38%), Gaps = 33/370 (8%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 ++ L +E + P +EV +++ +C +DV++WE P + G Sbjct: 8 AAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPL---FPRIFG 64 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFF---CATPPDD 126 HEA G VE VG V L+PGD V C N+ + D Sbjct: 65 HEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGMIHD 124 Query: 127 GN------------------LCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGIHA-CR 166 G + ++ K+ + ++ ++ LS G+ A Sbjct: 125 GESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGATLN 184 Query: 167 RGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK 226 G V + G G +G+ A+ GA++++ D ++ R +AKE G + K Sbjct: 185 VAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVN-PK 243 Query: 227 ESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSEMT----- 280 + + I + + + ++ECTG+ ++ G G VLVG+ S+ Sbjct: 244 DHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFKTH 303 Query: 281 TVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKK 340 + L+ + G ++ P + +K + ++ +TH P + +AF+ K Sbjct: 304 PMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDYMLK 363 Query: 341 GLGLKIMLKC 350 G ++ ++ Sbjct: 364 GESIRCIITM 373 >5YLN-A nrPDB Length = 356 Score = 266 bits (680), Expect = 1e-71, Method: Composition-based stats. Identities = 86/355 (24%), Positives = 148/355 (41%), Gaps = 15/355 (4%) Query: 10 LSLVVHGPGDLRLENYPIPEP-GPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVL 68 + PG + P P + ++R+ ICG+D+H + + +L Sbjct: 6 KAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVP---TCQSGTIL 62 Query: 69 GHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS-PSIFFCATPPDDG 127 GHE G VE+VG V + K GD+V I +CK G Y + DG Sbjct: 63 GHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHCEDEGGWIFGHLIDG 122 Query: 128 NLCRFYKHN--AAFCYKLPDNVTFEEGALI-EPLSVGIH-ACRRGGVTLGHKVLVCGAGP 183 + + Y P++++ E ++ + L G +G V G V + G+GP Sbjct: 123 MQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKGKVEPGCSVAIIGSGP 182 Query: 184 IGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKV-EGQLGC 242 +G+ LL A+ A++++ DL RL A GA + S P++ +++ + G Sbjct: 183 VGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSS--DPEKAIKEIYDLTDGR 240 Query: 243 KPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCN 302 +V IE G A+ G + G+ + L IR +++ N Sbjct: 241 GVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEFDLDKLWIRNINVTTGLVSTN 300 Query: 303 TWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL---GLKIMLKCDPSD 354 T P + L S + + LVTH F L + +A+E F K +K++++ D S+ Sbjct: 301 TTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSKAADHHAIKVIIENDISE 355 >6N7L-A nrPDB Length = 353 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 86/346 (24%), Positives = 144/346 (41%), Gaps = 15/346 (4%) Query: 7 PNNLSLVVHGPGD-LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKP 65 + VV G G+ L+++ P+ EPG EVL+++ + G+C +D+H + K P Sbjct: 12 KTMKAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAK--PKMP 69 Query: 66 MVLGHEASGTVEKVGSSVKHLKPGDRVAIEP-GAPRENDEFCKMGRYNLSPSIFFCATPP 124 ++ GHE G V G +K GD V + + ++C G L + Sbjct: 70 LIPGHEGVGIVVACGPDA-MVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQN-GGYS 127 Query: 125 DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGP 183 DG + ++ + L NV F E A I V ++ + G V + G G Sbjct: 128 VDGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVYKGLKETETKPGEWVAISGIGG 187 Query: 184 IGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCK 243 +G V + AKAMG V D++ +L AK++GADL + P K G + Sbjct: 188 LGHVAVQYAKAMGMH-VAAIDVADDKLELAKKLGADLTVNAKTTDPGTYLHKEVGGM--- 243 Query: 244 PEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNT 303 + + + + GI R G + L GL +P+ ++ + ++G Sbjct: 244 -HGALITAVSPIAFKQGIDVLRRKGTIALNGLPPGSFELPIFETVLKRITVRGSIVGTRK 302 Query: 304 WPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL-GLKIML 348 A++ + VK VT LE + F+ KKG +I+L Sbjct: 303 DLQEALDFANEGL-VKATVTSA-KLEDINDVFDKMKKGQIDGRIVL 346 >3MEQ-A nrPDB Length = 365 Score = 265 bits (678), Expect = 2e-71, Method: Composition-based stats. Identities = 79/346 (22%), Positives = 141/346 (40%), Gaps = 18/346 (5%) Query: 2 AAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI 61 + AK ++V L ++ PIP+PGP ++ + + + G+C +D+H E G++ Sbjct: 20 GSMAKTMKAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAE----GDWP 75 Query: 62 VKK--PMVLGHEASGTVEKVGSSVKHLKPGDRVAIEP-GAPRENDEFCKMGRYNLSPSIF 118 VK P + GHE G V VGS VKH+K GDRV I + C G L Sbjct: 76 VKPNPPFIPGHEGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEEQL 135 Query: 119 FCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVL 177 + G + + F LP N+ F E A + V ++ + G V+ Sbjct: 136 NTGYSVN-GGFAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVYKGLKVTDTKPGDWVV 194 Query: 178 VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK--ESPQEIARK 235 + G G +G + + A+AMG V D+ +L A+ +GA + + + I ++ Sbjct: 195 ISGIGGLGHMAVQYARAMGL-NVAAVDIDDRKLDLARRLGATVTVNAKTVADPAAYIRKE 253 Query: 236 VEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIK 295 +G + + + + + GG + L GL + + + + V ++ Sbjct: 254 TDGGAQG----VLVTAVSPKAFEQALGMVARGGTVSLNGLPPGDFPLSIFNMVLNGVTVR 309 Query: 296 GVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 G + S+ + VK + LE F+ ++G Sbjct: 310 GSIVGT-RLDLQESLDFAADGKVKATI-QTGKLEDINAIFDDMRQG 353 >4CPD-A nrPDB Length = 347 Score = 264 bits (675), Expect = 5e-71, Method: Composition-based stats. Identities = 94/349 (26%), Positives = 161/349 (46%), Gaps = 17/349 (4%) Query: 10 LSLVVHGPGDLRLENYPIPEPG-PNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVL 68 ++V + ++ P P + L+R+H GICGSD+H + G V VL Sbjct: 2 RAVVFENKERVAVKEVNAPRLQHPLDALVRVHLAGICGSDLHLYH----GKIPVLPGSVL 57 Query: 69 GHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGN 128 GHE G VE VG ++ L+PGD V +C+ +YNL P GN Sbjct: 58 GHEFVGQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPMFGN 117 Query: 129 L----CRFYKHNAAFC--YKLPDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGA 181 L + + KLP N++ E + LS +G + G V V GA Sbjct: 118 LQGAQAEILRVPFSNVNLRKLPPNLSPERAIFAGDILSTAYGGLIQGQLRPGDSVAVIGA 177 Query: 182 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLG 241 GP+G++ + VA+ +GA++++ D RL +A +GA + + +E+P R G Sbjct: 178 GPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGA-IPINAEQENPVRRVRSETNDEG 236 Query: 242 CKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMT-TVPLLHAAIREVDIK-GVFR 299 P++ +E G A++ + R GG + VG+ + + PL ++++ + G+ Sbjct: 237 --PDLVLEAVGGAATLSLALEMVRPGGRVSAVGVDNAPSFPFPLASGLVKDLTFRIGLAN 294 Query: 300 YCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 +++LAS + + +V+H PLE+A +E F + LK++L Sbjct: 295 VHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYELFDRKEALKVLL 343 >3S2F-A nrPDB Length = 340 Score = 260 bits (665), Expect = 6e-70, Method: Composition-based stats. Identities = 80/334 (23%), Positives = 143/334 (42%), Gaps = 17/334 (5%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMVLGHEASGTVE 77 L ++ P+P+PGP +V +++ + G+C +D+H + G++ VK P + GHE G V Sbjct: 15 LTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAAD----GDWPVKPTLPFIPGHEGVGYVS 70 Query: 78 KVGSSVKHLKPGDRVAIEP-GAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHN 136 VGS V +K GDRV + + E C G L + G + + Sbjct: 71 AVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQNTGYSVN-GGYGEYVVAD 129 Query: 137 AAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAM 195 + LPD V F E A I V ++ + G V++ G G +G V + A+AM Sbjct: 130 PNYVGLLPDKVGFVEIAPILCAGVTVYKGLKVTDTRPGQWVVISGIGGLGHVAVQYARAM 189 Query: 196 GAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEA 255 G +V D+ +L+ A+ +GA++ + P +K G + + Sbjct: 190 GL-RVAAVDIDDAKLNLARRLGAEVAVNARDTDPAAWLQKEIG----GAHGVLVTAVSPK 244 Query: 256 SIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKS 315 + I R GG + L GL P+ ++ + I+G + + S+ + Sbjct: 245 AFSQAIGMVRRGGTIALNGLPPGDFGTPIFDVVLKGITIRGSIVGTRS-DLQESLDFAAH 303 Query: 316 VNVKPLVTHRFPLEKALEAFETFKKGL-GLKIML 348 +VK V+ L+ + F ++G +++L Sbjct: 304 GDVKATVS-TAKLDDVNDVFGRLREGKVEGRVVL 336 >6DKH-A nrPDB Length = 346 Score = 260 bits (664), Expect = 8e-70, Method: Composition-based stats. Identities = 99/307 (32%), Positives = 160/307 (52%), Gaps = 11/307 (3%) Query: 33 NEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRV 92 N L+++ GICGSD+HY++ G++GNF++K PMVLGHE G V + S L G V Sbjct: 31 NGTLVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTV 88 Query: 93 AIEPGAPRENDEFCKMGRYNLSPSIFFCAT----PPDDGNLCRFYKHNAAFCYKLPDNVT 148 AI P P + ++C N + F + P DG R+ + C P Sbjct: 89 AINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKAD 148 Query: 149 FEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSAT 208 + A EPL+V IHA + G G +V + G GPIG + + K +GAA++V D+S Sbjct: 149 EKVMAFAEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPR 208 Query: 209 RLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGG 268 LS KE+GAD+++ + + + +G +V+ E +G +S+ + TR+ G Sbjct: 209 SLSLGKEMGADVLVNPQNDD-MDHWKAEKGYF----DVSFEVSGHPSSVNTCLEVTRARG 263 Query: 269 NLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPL 328 +V VG+G M P++ +E+ ++G FR+ + + A+S LA+ +N PL++ +P Sbjct: 264 VMVQVGMGGAMAEFPMMTLIGKEISLRGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPF 323 Query: 329 EKALEAF 335 EA Sbjct: 324 TDLEEAL 330 >1YKF-A nrPDB Length = 352 Score = 254 bits (648), Expect = 6e-68, Method: Composition-based stats. Identities = 88/344 (25%), Positives = 139/344 (40%), Gaps = 17/344 (4%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 + G + P PGP + ++R +V C SD+H G IG + M+LG Sbjct: 2 KGFAMLSIGKVGWIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGE---RHNMILG 58 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDG 127 HEA G V +VGS VK KPGDRV + P + G + S + + + DG Sbjct: 59 HEAVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDG 118 Query: 128 NLCRFYKHNAA--FCYKLPDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPI 184 F+ N A LP + E +I + ++ G H + LG V V G GP+ Sbjct: 119 VFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGAELADIELGATVAVLGIGPV 178 Query: 185 GMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 G++ + AK GA +++ + AK GA ++ K+ P E ++ + G Sbjct: 179 GLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNY-KDGPIE-SQIMNLTEGKGV 236 Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL----LHAAIREVDIKGVFRY 300 + I G + + + GG + V E +P+ + IKG Sbjct: 237 DAAIIAGGNADIMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKTIKGGLCP 296 Query: 301 CNTWPV--AISMLASKSVNVKPLVTHRFP-LEKALEAFETFKKG 341 + I ++ K V+ LVTH F + +AF K Sbjct: 297 GGRLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDK 340 >1R37-A nrPDB Length = 347 Score = 253 bits (645), Expect = 1e-67, Method: Composition-based stats. Identities = 89/339 (26%), Positives = 148/339 (43%), Gaps = 15/339 (4%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI------VKKPMVLGHEAS 73 L L+ +P+P +VL+++ + G+C SDVH + GR GN VK P+ LGHE + Sbjct: 13 LSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQ-GRFGNLRIVEDLGVKLPVTLGHEIA 71 Query: 74 GTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFY 133 G +E+VG V GD VA+ P N +C++G +L S + DG + Sbjct: 72 GKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLCDSPRWLGINF-DGAYAEYV 130 Query: 134 KHNA-AFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHK-VLVCGAGPIGMVTLLV 191 + YKL E L A R+ + ++V G +G + + + Sbjct: 131 IVPHYKYMYKLRRLNAVEAAPLTCSGITTYRAVRKASLDPTKTLLVVGAGGGLGTMAVQI 190 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECT 251 AKA+ A ++ D+ + AK GAD V+ S + P R++ G + I+ Sbjct: 191 AKAVSGATIIGVDVREEAVEAAKRAGADYVINASMQDPLAEIRRITESKG--VDAVIDLN 248 Query: 252 GAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISML 311 +E ++ A G V+VGL + E+ G + + I L Sbjct: 249 NSEKTLSVYPKALAKQGKYVMVGLFGADLHYHAPLITLSEIQFVGSLVGNQSDFLGIMRL 308 Query: 312 ASKSVNVKPLVTHRFPLEKALEAFETFK--KGLGLKIML 348 A VKP++T LE+A EA + + K +G ++++ Sbjct: 309 AEAG-KVKPMITKTMKLEEANEAIDNLENFKAIGRQVLI 346 >3FPC-A nrPDB Length = 352 Score = 250 bits (639), Expect = 7e-67, Method: Composition-based stats. Identities = 82/344 (23%), Positives = 131/344 (38%), Gaps = 17/344 (4%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 + G + P PGP + ++R +V C SD+H G IG + M+LG Sbjct: 2 KGFAMLSIGKVGWIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGE---RHNMILG 58 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDG 127 HEA G V +VGS VK KPGDRV + P + G + S + + + DG Sbjct: 59 HEAVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDG 118 Query: 128 NLCRFYKHNAA--FCYKLPDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPI 184 F+ N A LP + E +I + ++ G H + LG V V G GP+ Sbjct: 119 VFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGAELANIKLGDTVCVIGIGPV 178 Query: 185 GMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 G++++ A +GA ++ A E GA ++ E K G Sbjct: 179 GLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKG--V 236 Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL----LHAAIREVDIKGVFRY 300 + + G + + + G ++ V E + + + I G Sbjct: 237 DKVVIAGGDVHTFAQAVKMIKPGSDIGNVNYLGEGDNIDIPRSEWGVGMGHKHIHGGLCP 296 Query: 301 CNTWPV--AISMLASKSVNVKPLVTHRFP-LEKALEAFETFKKG 341 + I ++ K V+ LVTH F + +AF K Sbjct: 297 GGRLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDK 340 >4UEJ-A nrPDB Length = 346 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 92/350 (26%), Positives = 154/350 (44%), Gaps = 18/350 (5%) Query: 10 LSLVVHGPGDLRLENYPIPEPGP-NEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVL 68 S+V G +R+ IPE +EV +++ S G+CGSD+ + P+ L Sbjct: 2 KSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY----PITL 57 Query: 69 GHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGN 128 GHE SG ++ VGS V L PGD VA P P C G Y+ F + DG Sbjct: 58 GHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGS-RRDGG 116 Query: 129 LCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVT 188 + + LP ++ E+GA IEP++VG+HA V++ GAG IG++ Sbjct: 117 FAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLA 176 Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248 + A A+GA V D+S+ +L+ AK GA S+ S ++ + ++ + Sbjct: 177 IQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL--RFNQLIL 234 Query: 249 ECTGAEASIQAGIYATRSGGNLVLVGLGSEM---TTVPLLHAAIREVDIKGVFR------ 299 E G +++ + L LVG + T+ +E+ + G + Sbjct: 235 ETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPW 294 Query: 300 YCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKK-GLGLKIML 348 W A +L + ++++PL+ HR E +A + + K++L Sbjct: 295 PGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 >3FSR-A nrPDB Length = 352 Score = 249 bits (635), Expect = 2e-66, Method: Composition-based stats. Identities = 82/344 (23%), Positives = 134/344 (38%), Gaps = 17/344 (4%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 + G + P PGP + ++R +V C SD+H G IG + M+LG Sbjct: 2 KGFAMLSIGKVGWIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGE---RHNMILG 58 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDG 127 HEA G V +VGS VK KPGDRV + P + G + S + + + DG Sbjct: 59 HEAVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDG 118 Query: 128 NLCRFYKHNAA--FCYKLPDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPI 184 F+ N A LP + E +I + ++ G H + +G V+V G G + Sbjct: 119 VFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGAELADIQMGSSVVVIGIGAV 178 Query: 185 GMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 G++ + AK GA +++ + AK GA +L + K+ G Sbjct: 179 GLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGHIVDQVMKLTNGKG--V 236 Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL----LHAAIREVDIKGVFRY 300 + I G ++ + + GG + + + + + IKG Sbjct: 237 DRVIMAGGGSETLSQAVSMVKPGGIISNINYHGSGDALLIPRVEWGCGMAHKTIKGGLCP 296 Query: 301 CNTWPV--AISMLASKSVNVKPLVTHRFP-LEKALEAFETFKKG 341 + I ++ K V+ LVTH F + +AF K Sbjct: 297 GGRLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDK 340 >4EEZ-A nrPDB Length = 348 Score = 248 bits (634), Expect = 3e-66, Method: Composition-based stats. Identities = 88/336 (26%), Positives = 150/336 (44%), Gaps = 12/336 (3%) Query: 10 LSLVVHGP-GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVL 68 ++V H P G L + PNE LL M G+C +D+H G+F K VL Sbjct: 3 AAVVRHNPDGYADLVEKELRAIKPNEALLDMEYCGVCHTDLHV----AAGDFGNKAGTVL 58 Query: 69 GHEASGTVEKVGSSVKHLKPGDRVAIEPG-APRENDEFCKMGRYNLSPSIFFCATPPDDG 127 GHE G V+++G+ V L+ GDRV++ + E+C G + DG Sbjct: 59 GHEGIGIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFCREVKNAG-YSVDG 117 Query: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGM 186 + A + K+PD + E + I V + A + GV G ++ GAG +G Sbjct: 118 GMAEEAIVVADYAVKVPDGLDPIEASSITCAGVTTYKAIKVSGVKPGDWQVIFGAGGLGN 177 Query: 187 VTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEV 246 + + AK + A+V+ D++ +L+ AK+IGAD+ + +P + +K+ G LG + Sbjct: 178 LAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDVNPVDEIKKITGGLGVQS-- 235 Query: 247 TIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPV 306 I C A + + + + + G +V V + + T+ + V++ G + Sbjct: 236 AIVCAVARIAFEQAVASLKPMGKMVAVAVPNTEMTLSVPTVVFDGVEVAGSLVGT-RLDL 294 Query: 307 AISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 A + VKP+V R LE+ + + K G Sbjct: 295 AEAFQFGAEGKVKPIVATR-KLEEINDIIDEMKAGK 329 >1H2B-A nrPDB Length = 359 Score = 247 bits (631), Expect = 5e-66, Method: Composition-based stats. Identities = 77/331 (23%), Positives = 141/331 (42%), Gaps = 16/331 (4%) Query: 20 LRLENYPIPEP-GPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEK 78 LR+E+ P G +V++R+ G+C +D+H + K P LGHE G +E+ Sbjct: 28 LRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPKLPYTLGHENVGYIEE 87 Query: 79 VGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAA 138 V V+ L+ GD V + P C+ G ++ F DG F + + Sbjct: 88 VAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEFPGLNI-DGGFAEFMRTSHR 146 Query: 139 FCYKLPDNVTFEEGALIEPLS----VGIHACRRGGVT--LGHKVLVCGAGPIGMVTLLVA 192 KLP +++ E+ + PL+ A ++ T G V + G G +G + + + Sbjct: 147 SVIKLPKDISREKLVEMAPLADAGITAYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLL 206 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTG 252 K M A V+ D+ +L A+ +GAD V+ ++ +++ G V ++ G Sbjct: 207 KVMTPATVIALDVKEEKLKLAERLGADHVVDARRDPVKQVMELTR---GRGVNVAMDFVG 263 Query: 253 AEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCN-TWPVAISML 311 ++A++ Y G L++VG G E+ P + EV +G +++ Sbjct: 264 SQATVDYTPYLLGRMGRLIIVGYGGEL-RFPTIRVISSEVSFEGSLVGNYVELHELVTLA 322 Query: 312 ASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 V V+ + L++ + E +KG Sbjct: 323 LQGKVRVEVDI---HKLDEINDVLERLEKGE 350 >3FPL-A nrPDB Length = 351 Score = 247 bits (631), Expect = 5e-66, Method: Composition-based stats. Identities = 84/344 (24%), Positives = 137/344 (39%), Gaps = 17/344 (4%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 + G L P G + ++R +V C SD+H G +G+ +K M+LG Sbjct: 2 KGFAMLGINKLGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGD---RKNMILG 58 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDG 127 HEA G V +VGS VK KPGDRV + P + G S + + + DG Sbjct: 59 HEAVGEVVEVGSEVKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDG 118 Query: 128 NLCRFYKHNAA--FCYKLPDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPI 184 ++ N A LP ++ E +I + ++ G H + LG V V G GP+ Sbjct: 119 VFGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGAELADIELGATVAVLGIGPV 178 Query: 185 GMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 G++ + AK GA +++ + AK GA ++ K+ P E ++ + G Sbjct: 179 GLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNY-KDGPIE-SQIMNLTEGKGV 236 Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL----LHAAIREVDIKGVFRY 300 + I G + + + GG + V E +P+ + IKG Sbjct: 237 DAAIIAGGNADIMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKTIKGGLCP 296 Query: 301 CNTWPVAI--SMLASKSVNVKPLVTHRFP-LEKALEAFETFKKG 341 + M+ V++ LVTH + + EA K Sbjct: 297 GGRLRAEMLRDMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDK 340 >1P0F-A nrPDB Length = 373 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 84/366 (22%), Positives = 140/366 (38%), Gaps = 33/366 (9%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 ++ L LE + P +EV +++ + GICGSD + K P++LG Sbjct: 12 AAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEI----IPSKFPVILG 67 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS--------------- 114 HEA G VE +G+ V +KPGD+V + CK N Sbjct: 68 HEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAKTGLMADM 127 Query: 115 PSIFFCATPP-----DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHA-CRRG 168 S F C P + K+ E + + G A Sbjct: 128 TSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLESCLIGCGFATGYGAAVNTA 187 Query: 169 GVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKES 228 VT G V G G +G ++ KA GA++++ + KA E+GA L K+ Sbjct: 188 KVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATECLN-PKDY 246 Query: 229 PQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSEMT-----TV 282 + I + + + +EC G ++ + +T G G V++GL S + Sbjct: 247 DKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNERLPLDPL 306 Query: 283 PLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 LL + + G F+ + K +NV LV+ + L++ +AFE G Sbjct: 307 LLLTGRSLKGSVFGGFKG-EEVSRLVDDYMKKKINVNFLVSTKLTLDQINKAFELLSSGQ 365 Query: 343 GLKIML 348 G++ ++ Sbjct: 366 GVRSIM 371 >1KEV-A nrPDB Length = 351 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 78/344 (22%), Positives = 132/344 (38%), Gaps = 17/344 (4%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 + G L P G + ++R +V C SD+H G +G+ +K M+LG Sbjct: 2 KGFAMLGINKLGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGD---RKNMILG 58 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDG 127 HEA G V +VGS VK KPGDRV + P + G S + + + DG Sbjct: 59 HEAVGEVVEVGSEVKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDG 118 Query: 128 NLCRFYKHNAA--FCYKLPDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPI 184 ++ N A LP ++ E +I + ++ G H + +G V+V G G + Sbjct: 119 VFGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGAELADIQMGSSVVVIGIGAV 178 Query: 185 GMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 G++ + AK GA +++ + AK GA +L + K+ G Sbjct: 179 GLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGHIVDQVMKLTNGKG--V 236 Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL----LHAAIREVDIKGVFRY 300 + I G ++ + + GG + + + + + IKG Sbjct: 237 DRVIMAGGGSETLSQAVSMVKPGGIISNINYHGSGDALLIPRVEWGCGMAHKTIKGGLCP 296 Query: 301 CNTWPVAI--SMLASKSVNVKPLVTHRFP-LEKALEAFETFKKG 341 + M+ V++ LVTH + + EA K Sbjct: 297 GGRLRAEMLRDMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDK 340 >5ENV-A nrPDB Length = 347 Score = 241 bits (614), Expect = 5e-64, Method: Composition-based stats. Identities = 79/335 (23%), Positives = 143/335 (42%), Gaps = 12/335 (3%) Query: 12 LVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHE 71 + G L ++ P+P+P NE+L+ + G+C +D+H W VK P+V GHE Sbjct: 10 IFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDW--PLPVKLPLVGGHE 67 Query: 72 ASGTVEKVGSSVKHLKPGDRVAIEP-GAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLC 130 +G V +G +VK K GD I+ E+C++G + P DG+ Sbjct: 68 GAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLSG-YTHDGSFQ 126 Query: 131 RFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCG-AGPIGMVT 188 ++ +A +P + A I + ++ A + + GH V + G AG +G + Sbjct: 127 QYATADAVQAAHIPQGTDLAQVAPILCAGITVYKALKSANLMAGHWVAISGAAGGLGSLA 186 Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248 + AKAMG +V+ D + + IG ++ + +KE ++I V I Sbjct: 187 VQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTKE--KDIVGAVLKATDGGAHGVI 243 Query: 249 ECTGAEASIQAGIYATRSGGNLVLVGLGSEMT-TVPLLHAAIREVDIKGVFRYCNTWPVA 307 + +EA+I+A R+ G VLVG+ + + + ++ + I G + Sbjct: 244 NVSVSEAAIEASTRYVRANGTTVLVGMPAGAKCCSDVFNQVVKSISIVGSYVGNRADTRE 303 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 ++ + P+ L E +E +KG Sbjct: 304 ALDFFARGLVKSPI--KVVGLSTLPEIYEKMEKGQ 336 >5K1S-A nrPDB Length = 362 Score = 240 bits (612), Expect = 7e-64, Method: Composition-based stats. Identities = 94/337 (27%), Positives = 155/337 (45%), Gaps = 15/337 (4%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI-VKKPMVLGHEASGTV 76 G+L++E P+P PG EVLLR+H+ G+C DV R GN P +LGHEA+G V Sbjct: 30 GNLKMETMPMPRPGRGEVLLRVHACGVCYHDV----INRRGNLPRTSVPAILGHEAAGEV 85 Query: 77 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHN 136 +VG K GDR A + C+ GR +L + G +F Sbjct: 86 IEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTDNRFFGEELPGGYAQFMVAP 145 Query: 137 AAFCYKLPDNVTFEEGALIEP-LSVGIHACR-RGGVTLGHKVLVCGA-GPIGMVTLLVAK 193 ++P ++ + E A + +H R RG V G VL+ GA G +G+ ++ +A+ Sbjct: 146 VGGLGRVPASLPWNEAATVCCTTGTAVHTVRTRGKVRAGETVLITGASGGVGLSSVQLAR 205 Query: 194 AMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGA 253 GA +V+ S ++ KE GAD V+ RK G +V +E G+ Sbjct: 206 LDGA-RVIAVTSSEAKVQALKEAGADEVIVSRGLDFASDVRKRT--QGAGVDVAVEIVGS 262 Query: 254 EASIQAGIYATRSGGNLVLVG-LGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLA 312 A+ + + GG +V+VG L S M + ++E++I G + + ++ Sbjct: 263 -ATFDQTLKSMAPGGRVVVVGNLESGMVQLNPGLVIVKELEILGAYATTQA-ELDEALRL 320 Query: 313 SKSVNVKPLVTHRFPLEKALEA-FETFKKGLGLKIML 348 + + V+ VT PL +A +A F + + +++L Sbjct: 321 TATGGVRQFVTDAVPLAEAAKAHFRLENREVAGRLVL 357 >2OUI-A nrPDB Length = 360 Score = 239 bits (611), Expect = 1e-63, Method: Composition-based stats. Identities = 84/342 (24%), Positives = 139/342 (40%), Gaps = 17/342 (4%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 L + G G + IPE GP + L+R ++ C SD H G IG+ + M+LG Sbjct: 2 KGLAMLGIGRIGWIEKKIPECGPLDALVRPLALAPCTSDTHTVWAGAIGD---RHDMILG 58 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDG 127 HEA G + KVGS VK LK GD+V + P +E + G S + + + DG Sbjct: 59 HEAVGQIVKVGSLVKRLKVGDKVIVPAITPDWGEEESQRGYPMHSGGMLGGWKFSNFKDG 118 Query: 128 NLCRFYKHNAA--FCYKLPDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPI 184 + N A LP ++ E+ ++ + ++ G H + LG V V G GP+ Sbjct: 119 VFSEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGAELANIKLGDTVCVIGIGPV 178 Query: 185 GMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 G++++ A +GA ++ A E GA ++ E K G Sbjct: 179 GLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKG--V 236 Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL----LHAAIREVDIKGVFRY 300 + + G + + + G ++ V E +P+ + I G Sbjct: 237 DKVVIAGGDVHTFAQAVKMIKPGSDIGNVNYLGEGDNIPIPRSEWGVGMGHKHIHGGLTP 296 Query: 301 CNTWP--VAISMLASKSVNVKPLVTHRFP-LEKALEAFETFK 339 S++++ ++ L+THRF LEK +A K Sbjct: 297 GGRVRMEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMK 338 >3IP1-A nrPDB Length = 404 Score = 236 bits (603), Expect = 8e-63, Method: Composition-based stats. Identities = 93/356 (26%), Positives = 159/356 (44%), Gaps = 31/356 (8%) Query: 19 DLRLENYPIPEP-GPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVK----KPMVLGHEAS 73 ++R+E P P P E+++++ + GICGSDVH + G + P+ LGHE S Sbjct: 41 EVRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGHEFS 100 Query: 74 GTVEKVGSSV------KHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDG 127 G V + G K + G+ V E + C G N ++ DG Sbjct: 101 GVVVEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLNELGFNV-DG 159 Query: 128 NLCRFYKHNAAFCYKLPD-------NVTFEEGALIEPLSVGIHAC--RRGGVTLGHKVLV 178 + K +A + + L + + F G+L+EP SV +A R GG+ G V++ Sbjct: 160 AFAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLVEPTSVAYNAVIVRGGGIRPGDNVVI 219 Query: 179 CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEG 238 G GPIG+ + + K GA++V++++ S R + AKE+GAD V+ +KE+ E Sbjct: 220 LGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDPTKENFVEAVLDYTN 279 Query: 239 QLGCKPEVTIECTGAEASIQAGIYAT---RSGGNLVLVGLGSEMTTVPLLHAA--IREVD 293 LG K + +E TG + I G N + + +PL +R Sbjct: 280 GLGAK--LFLEATGVPQLVWPQIEEVIWRARGINATVAIVARADAKIPLTGEVFQVRRAQ 337 Query: 294 IKGVFRYC--NTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIM 347 I G + T+P IS++AS +++ +++ +E+ E + + L + Sbjct: 338 IVGSQGHSGHGTFPRVISLMASG-MDMTKIISKTVSMEEIPEYIKRLQTDKSLVKV 392 >1F8F-A nrPDB Length = 371 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 79/361 (21%), Positives = 136/361 (37%), Gaps = 39/361 (10%) Query: 19 DLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEK 78 D L+ I +P +EVL+++ + G+C +D+ R + V P VLGHE SG +E Sbjct: 18 DFELQALKIRQPQGDEVLVKVVATGMCHTDLIV----RDQKYPVPLPAVLGHEGSGIIEA 73 Query: 79 VGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDG----------- 127 +G +V L+ GD V + G C G F D Sbjct: 74 IGPNVTELQVGDHVVLSYGY-CGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHALCTHDQ 132 Query: 128 -----------NLCRFYKHNAAFCYKLPDNVTFEEGALIEP-LSVGIHACRRG-GVTLGH 174 + + K+ +V E + + G AC VT Sbjct: 133 GVVNDHFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACINALKVTPAS 192 Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 234 + GAG +G+ LL AK GA+ ++ D+ +RL AK++GA V+ + P + Sbjct: 193 SFVTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSKTQDPVAAIK 252 Query: 235 KVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLG--SEMTTVPLLHAAIREV 292 ++ +E TG+ ++ G+ A G + +VG + + Sbjct: 253 EITDG---GVNFALESTGSPEILKQGVDALGILGKIAVVGAPQLGTTAQFDVNDLLLGGK 309 Query: 293 DIKGVFRYCNT----WPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 I GV + P + + LV + ++ +A +KG+ LK ++ Sbjct: 310 TILGVVEGSGSPKKFIPELVRLYQQGKFPFDQLV-KFYAFDEINQAAIDSRKGITLKPII 368 Query: 349 K 349 K Sbjct: 369 K 369 >5TNX-A nrPDB Length = 383 Score = 226 bits (577), Expect = 9e-60, Method: Composition-based stats. Identities = 87/363 (23%), Positives = 137/363 (37%), Gaps = 45/363 (12%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 +E I P +EVL+R+ + G+C +D+ R + V P VLGHE +G VE V Sbjct: 30 FSIEPARIRAPRGDEVLVRVVATGLCHTDLIV----RDQYYPVPLPAVLGHEGAGVVEAV 85 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF--FCATPPDDG---------- 127 G +VK L GD V + GA + C G F DG Sbjct: 86 GPNVKTLAAGDHVVLTYGA-CGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGE 144 Query: 128 ----------NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHA-----CRRGGVTL 172 + + K+P E L+ PL GI V Sbjct: 145 PLHDHFFAQSSFASYALARENNAIKVPKEAPLE---LLGPLGCGIQTGAGAVINSLAVRT 201 Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 G GAG +GM ++ A+ GA ++ D+ +RL+ A E+GA + + + Sbjct: 202 GSSFASFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVDVVDA 261 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLG--SEMTTVPLLHAAIR 290 R++ G + +E TG A + GI A S G + +VG + + Sbjct: 262 IREIT---GGGVDYALESTGLPAVLSQGIDALGSRGTMGVVGAPKLGTKAEFDVNSLLLG 318 Query: 291 EVDIKGVFRYCNT----WPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKI 346 I+G+ + P + + LV +PLE+ +A G+ LK Sbjct: 319 GHTIRGIVEGDSVPQTFIPQLVQLHLQGRFPFDRLV-KFYPLEQINQAAADSSSGITLKP 377 Query: 347 MLK 349 +L+ Sbjct: 378 ILR 380 >5YAT-A nrPDB Length = 350 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 75/349 (21%), Positives = 148/349 (42%), Gaps = 13/349 (3%) Query: 1 MAAAAKPNNLSLVVHG-PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGN 59 M+ +++ G L ++ P+P+P NE+L+ + G+C +D+H W+ Sbjct: 1 MSPTIPTTQKAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDW--P 58 Query: 60 FIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEP-GAPRENDEFCKMGRYNLSPSIF 118 K P+V GHE +G V G +V + GD I+ N E+C G + Sbjct: 59 LDNKLPLVGGHEGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKAD 118 Query: 119 FCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVL 177 DG+ ++ +A ++P E A I + ++ A + + +G V Sbjct: 119 LSGF-THDGSFQQYATADATQAARIPKEADLAEVAPILCAGITVYKALKTADLRIGQWVA 177 Query: 178 V-CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKV 236 + G +G + + AKA+G +V+ D A + K +GA++ + +K +++ +V Sbjct: 178 ISGAGGGLGSLAVQYAKALGL-RVLGIDGGADKGEFVKSLGAEVFVDFTKT--KDVVAEV 234 Query: 237 EGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTV-PLLHAAIREVDIK 295 + P I + + +I + R+ G +VLVGL S + ++ ++IK Sbjct: 235 QKLTNGGPHGVINVSVSPHAINQSVQYVRTLGKVVLVGLPSGAVVNSDVFWHVLKSIEIK 294 Query: 296 GVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL 344 G + L ++ + VK + L + + +E + G + Sbjct: 295 GSYVGNREDSAEAIDLFTRGL-VKAPI-KIIGLSELAKVYEQMEAGAII 341 >4GKV-A nrPDB Length = 336 Score = 221 bits (563), Expect = 4e-58, Method: Composition-based stats. Identities = 82/335 (24%), Positives = 141/335 (42%), Gaps = 13/335 (3%) Query: 10 LSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69 + VV + + + E LL+M G+C +D+H + G+F K ++LG Sbjct: 2 KAAVVTKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHV----KNGDFGDKTGVILG 57 Query: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGA-PRENDEFCKMGRYNLSPSIFFCATPPDDGN 128 HE G V +VG V LKPGDR ++ + E+C G L S+ DG Sbjct: 58 HEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGY-SVDGG 116 Query: 129 LCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGMV 187 + A + K+PD + + I V + A + + G + + G G +G + Sbjct: 117 MAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIRPGQWIAIYGLGGLGNL 176 Query: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVT 247 L AK + A+V+ D++ +L A E+GADL + E +I ++ G Sbjct: 177 ALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDAAKIVQEKTGGAHAAVV-- 234 Query: 248 IECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVA 307 A+A+ + + A R+GG +V VGL E ++ + + +++ G + Sbjct: 235 --TAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDGIEVVGSLVGTRQ-DLT 291 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 + + V P V R PL F ++G Sbjct: 292 EAFQFAAEGKVVPKVALR-PLADINTIFTEMEEGK 325 >2H6E-A nrPDB Length = 344 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 77/329 (23%), Positives = 140/329 (42%), Gaps = 13/329 (3%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVE 77 L +E+ IPEP EVL+R+ G+C +D+ W+ G + P++LGHE +GT+ Sbjct: 14 EPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWK-GVEAKQGFRLPIILGHENAGTIV 72 Query: 78 KVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNA 137 +VG K +K GD V + +C+ G++N+ + + G ++ Sbjct: 73 EVGELAK-VKKGDNVVVYATWGDLTCRYCREGKFNICKNQIIPGQTTNGGFSEYMLVKSS 131 Query: 138 AFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGH----KVLVCGAGPIGMVTLLVAK 193 + KL E L + + + A R+ + V+V G G + + T+ + K Sbjct: 132 RWLVKLNSLSPVEAAPLADAGTTSMGAIRQALPFISKFAEPVVIVNGIGGLAVYTIQILK 191 Query: 194 A-MGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTG 252 A M +V S A E+GAD V + + + K+ LG + I+ G Sbjct: 192 ALMKNITIVGISRSKKHRDFALELGADYV--SEMKDAESLINKLTDGLGA--SIAIDLVG 247 Query: 253 AEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLA 312 E + G ++LVG+ + ++ A+ + G Y + + + Sbjct: 248 TEETTYNLGKLLAQEGAIILVGMEGKRVSLEAFDTAVWNKKLLGS-NYGSLNDLEDVVRL 306 Query: 313 SKSVNVKPLVTHRFPLEKALEAFETFKKG 341 S+S +KP + + PL+ +AF +G Sbjct: 307 SESGKIKPYII-KVPLDDINKAFTNLDEG 334 >6FG0-A nrPDB Length = 352 Score = 214 bits (544), Expect = 7e-56, Method: Composition-based stats. Identities = 73/330 (22%), Positives = 133/330 (40%), Gaps = 15/330 (4%) Query: 21 RLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVG 80 + + P P PGP E+LL++ + G+C SD+ + + P+ LGHE GTV ++G Sbjct: 14 VVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDM-PAAQYAGGLPLTLGHEGVGTVAELG 72 Query: 81 SSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP----DDGNLCRFYKHN 136 V GD VA+ C GR N P G++ + + Sbjct: 73 EGVTGFGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGITPPGYGSPGSMAEYMIVD 132 Query: 137 -AAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGHKVLVCGAGPIGMVTLLVAK 193 A + D L + HA R + G +V G G +G V + + + Sbjct: 133 SARHLVPIGDLDPVAAAPLTDAGLTPYHAISRVLPLLGPGSTAVVIGVGGLGHVGIQILR 192 Query: 194 AMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGA 253 A+ AA+V+ DL RL+ A+E+GAD ++ S + R++ G G + GA Sbjct: 193 AVSAARVIAVDLDDDRLALAREVGADAAVK-SGAGAADAIRELTGGQGATA--VFDFVGA 249 Query: 254 EASIQAGIYATRSGGNLVLVGL-GSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLA 312 +++I G++ +VG+ V + + + +++ Sbjct: 250 QSTIDTAQQVVAVDGHISVVGIHAGAHAKVGFWMIPFGASVVTPYWGTRSELMEVVALAR 309 Query: 313 SKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 + +++ T F L++ A+ ++G Sbjct: 310 AGRLDIH---TETFTLDEGPAAYRRLREGS 336 >3WLE-A nrPDB Length = 341 Score = 207 bits (528), Expect = 4e-54, Method: Composition-based stats. Identities = 85/343 (24%), Positives = 141/343 (41%), Gaps = 23/343 (6%) Query: 2 AAAAKPNNLSLVVHGPGDLRLE-NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF 60 A + + V + L+L + P+ +P ++LL++ +VG+C SD+H G Sbjct: 5 AMSIPSSQYGFVFNKQSGLKLRNDLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEG----L 60 Query: 61 IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF-- 118 V+GHE +GTV VG V + K GDRVA ++C+ N+ + F Sbjct: 61 DCGDNYVMGHEIAGTVAAVGDDVINYKVGDRVACVGPNGCGGCKYCRGAIDNVCKNAFGD 120 Query: 119 FCATPPDDGNLCRFYKHNAAFCYKLPDNVTFE-EGALIEPLSVGIHACRRGGVTLGHKVL 177 + D G ++PDNV+ + A + + HA + V+ +L Sbjct: 121 WFGLGYDGGYQQYLLVTRPRNLSRIPDNVSADVAAASTDAVLTPYHAIKMAQVSPTSNIL 180 Query: 178 VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVE 237 + GAG +G + VAKA GA +V V D +AK++GAD V + ES Sbjct: 181 LIGAGGLGGNAIQVAKAFGA-KVTVLDKKKEARDQAKKLGADAVYETLPESISP------ 233 Query: 238 GQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGV 297 + +A+ G ++ VGLG+ + L A+RE+ I G Sbjct: 234 ----GSFSACFDFVSVQATFDVCQKYVEPKGVIMPVGLGAPNLSFNLGDLALREIRILGS 289 Query: 298 F-RYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFK 339 F N + +++ V V L++ E E + Sbjct: 290 FWGTTNDLDDVLKLVSEGKVKP---VVRSAKLKELPEYIEKLR 329 >3UOG-A nrPDB Length = 363 Score = 205 bits (522), Expect = 2e-53, Method: Composition-based stats. Identities = 76/338 (22%), Positives = 139/338 (41%), Gaps = 18/338 (5%) Query: 17 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTV 76 P DL+L P+PE G +++++R +V + D E G + P V + SG V Sbjct: 38 PHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGM--GLDLAFPFVPASDMSGVV 95 Query: 77 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHN 136 E VG SV +PGDRV + GR + G L + Sbjct: 96 EAVGKSVTRFRPGDRVISTFAPGWLDGLRPGTGR----TPAYETLGGAHPGVLSEYVVLP 151 Query: 137 AAFCYKLPDNVTFEEGALIEPLSVGIH--ACRRGGVTLGHKVLVCGAGPIGMVTLLVAKA 194 + P ++ E + + + +G + G +V+V G G + + L +AKA Sbjct: 152 EGWFVAAPKSLDAAEASTLPCAGLTAWFALVEKGHLRAGDRVVVQGTGGVALFGLQIAKA 211 Query: 195 MGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAE 254 GA +V+VT S +L +A +GAD + +E E + G G + +E G Sbjct: 212 TGA-EVIVTSSSREKLDRAFALGADHGINRLEEDWVERVYALTGDRGA--DHILEIAGG- 267 Query: 255 ASIQAGIYATRSGGNLVLVGLGSE-MTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLAS 313 A + + A G + ++G+ + P+ ++ ++G+ A+ L Sbjct: 268 AGLGQSLKAVAPDGRISVIGVLEGFEVSGPVGPLLLKSPVVQGISVG---HRRALEDLVG 324 Query: 314 K--SVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLK 349 + +KP++ R+ + EA +G K++++ Sbjct: 325 AVDRLGLKPVIDMRYKFTEVPEALAHLDRGPFGKVVIE 362 >3TWO-A nrPDB Length = 348 Score = 192 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 64/359 (17%), Positives = 115/359 (32%), Gaps = 38/359 (10%) Query: 12 LVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHE 71 + + ++ GP +VL+ + GIC SD+H PM+ GHE Sbjct: 9 AIFSKDEHFKPHDFSRHAVGPRDVLIDILYAGICHSDIHSAYSEWKEGI---YPMIPGHE 65 Query: 72 ASGTVEKVGSSVKHLKPGDRVAIEPGA-PRENDEFCKMGRYNLSPSIF--------FCAT 122 +G +++VG VK K GD V + + + CK + + F Sbjct: 66 IAGIIKEVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKVVFTYDCLDSFHDN 125 Query: 123 PPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLS-VGIHACRRGGVTLGHKVLVCGA 181 P G + + + N E+ A + + VT G KV V G Sbjct: 126 EPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTYSPLKFSKVTKGTKVGVAGF 185 Query: 182 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLG 241 G +G + + A AMGA +V V + + A +G K+ +E+ Sbjct: 186 GGLGSMAVKYAVAMGA-EVSVFARNEHKKQDALSMGVKHFYTDPKQCKEEL--------- 235 Query: 242 CKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL---LHAAIREVDIKGVF 298 + I ++ + G+L LVGL L + + G Sbjct: 236 ---DFIISTIPTHYDLKDYLKLLTYNGDLALVGLPPVEVAPVLSVFDFIHLGNRKVYGSL 292 Query: 299 RYC-NTWPVAISMLASKSV--NVKPLVTHRFPLEKALEAFETFKKGLG-LKIMLKCDPS 353 + ++ + ++ A+ G + ++ S Sbjct: 293 IGGIKETQEMVDFSIKHNIYPEIDLILGK-----DIDTAYHNLTHGKAKFRYVIDMKKS 346 >1UUF-A nrPDB Length = 369 Score = 191 bits (486), Expect = 3e-49, Method: Composition-based stats. Identities = 72/343 (20%), Positives = 118/343 (34%), Gaps = 44/343 (12%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79 L + EPGPN+V + + G+C SD+H G P V GHE G V V Sbjct: 35 LEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTV---YPCVPGHEIVGRVVAV 91 Query: 80 GSSVKHLKPGDRVAIEPGA-PRENDEFCKMGRYNLSPSIF-FCATPPDD------GNLCR 131 G V+ PGD V + ++ E C+ G N + +P D G + Sbjct: 92 GDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPDEPGHTLGGYSQ 151 Query: 132 FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGP-------- 183 + + ++ E+ A + PL G+T + AGP Sbjct: 152 QIVVHERYVLRIR--HPQEQLAAVAPLLC-------AGITTYSPLRHWQAGPGKKVGVVG 202 Query: 184 ---IGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL 240 +G + + +A AMGA V T S + AK +GAD V+ K Sbjct: 203 IGGLGHMGIKLAHAMGAHVVAFTT-SEAKREAAKALGADEVVNSRNADEMAAHLK----- 256 Query: 241 GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVP-LLHAAIREVDIKGV-F 298 + + A ++ + G + LVG + P + + ++ I G Sbjct: 257 --SFDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKSPEVFNLIMKRRAIAGSMI 314 Query: 299 RYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 + A + ++ EA+E +G Sbjct: 315 GGIPETQEMLDFCAEHGIVAD---IEMIRADQINEAYERMLRG 354 >1YB5-A nrPDB Length = 351 Score = 191 bits (485), Expect = 5e-49, Method: Composition-based stats. Identities = 83/348 (23%), Positives = 142/348 (40%), Gaps = 49/348 (14%) Query: 14 VHGPGDLRLE-NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMVLGH 70 GP L+L + +P P ++VL+++H+ G+ + + R G + K P G Sbjct: 38 FGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYI----RSGTYSRKPLLPYTPGS 93 Query: 71 EASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLC 130 + +G +E VG + K GDRV + G Sbjct: 94 DVAGVIEAVGDNASAFKKGDRV---------------------------FTSSTISGGYA 126 Query: 131 RFYKHNAAFCYKLPDNVTFEEGALIE-PLSVGIHA-CRRGGVTLGHKVLVCGA-GPIGMV 187 + YKLP+ + F++GA I P A V G VLV GA G +G+ Sbjct: 127 EYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLA 186 Query: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVT 247 +A+A G +++ T + + GA V + + + +K G+ G ++ Sbjct: 187 ACQIARAYGL-KILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGI--DII 243 Query: 248 IECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNT---- 303 IE A ++ + GG +++VG + P A +E I GV + +T Sbjct: 244 IEML-ANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMA-KESSIIGVTLFSSTKEEF 301 Query: 304 WPVAISMLASKSVN-VKPLVTHRFPLEKALEAFETFKKGLG--LKIML 348 A ++ A + +KP++ ++PLEK EA E G G K++L Sbjct: 302 QQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMIL 349 >4A10-A nrPDB Length = 447 Score = 189 bits (480), Expect = 2e-48, Method: Composition-based stats. Identities = 85/351 (24%), Positives = 139/351 (39%), Gaps = 40/351 (11%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYW------------EYGRIGNFIVKKP-- 65 LRL P+PE P+EVL+ + + I + V + R G + + Sbjct: 50 LRLGEVPMPELAPDEVLVAVMASSINYNTVWSAMFEPIPTFHFLKQNARQGGWATRHDQP 109 Query: 66 -MVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP 124 VLG + SG V + G V+ KPGD V + P A + E G L Sbjct: 110 YHVLGSDCSGVVVRTGIGVRRWKPGDHVIVHP-AHVDEQEPATHGDGMLGTEQRAWGFET 168 Query: 125 DDGNLCRFYKHNAAFCYKLPDNVTFEEGALI-EPLSVGIHAC---RRGGVTLGHKVLVCG 180 + G L + A+ P ++T+EE A+ R + G VL+ G Sbjct: 169 NFGGLAEYGVVRASQLLPKPAHLTWEEAAVSPLCAGTAYRMLVSDRGAQMKQGDIVLIWG 228 Query: 181 A-GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK------------- 226 A G +G + K G V V SA + + + +G DLV+ ++ Sbjct: 229 ASGGLGSYAIQFVKNGGGIPVAVV-SSAQKEAAVRALGCDLVINRAELGITDDIADDPRR 287 Query: 227 --ESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSE-MTTVP 283 E+ +++A+ V + G +P++ E TG + + R GG +V G S + T Sbjct: 288 VVETGRKLAKLVVEKAGREPDIVFEHTGR-VTFGLSVIVARRGGTVVTCGSSSGYLHTFD 346 Query: 284 LLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEA 334 + ++ I G + A + L S V P ++ +PL +A EA Sbjct: 347 NRYLWMKLKKIVGSHGANHEEQQATNRLFE-SGAVVPAMSAVYPLAEAAEA 396 >1YQX-A nrPDB Length = 366 Score = 187 bits (474), Expect = 9e-48, Method: Composition-based stats. Identities = 74/333 (22%), Positives = 120/333 (36%), Gaps = 23/333 (6%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVE 77 G L N+ G +V ++ G+C SD+H + P+V GHE G V Sbjct: 27 GHLSPFNFSRRATGEEDVRFKVLYCGVCHSDLHSIKNDWG---FSMYPLVPGHEIVGEVT 83 Query: 78 KVGSSVKHLKPGDRVAIEPGAP-RENDEFCKMGRYNLSPSIFF-CATPPDD-----GNLC 130 +VGS VK + GD+V + + E C N P + A+ D G Sbjct: 84 EVGSKVKKVNVGDKVGVGCLVGACHSCESCANDLENYCPKMILTYASIYHDGTITYGGYS 143 Query: 131 RFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGHKVLVCGAGPIGMVT 188 N + + PDN+ + GA + + +++ + G G + + G G +G V Sbjct: 144 NHMVANERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGGLGHVA 203 Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248 + AKA G+ V++ + + K GAD L QE + G L + I Sbjct: 204 VKFAKAFGSKVTVISTSPSKKEEALKNFGADSFLVSRD---QEQMQAAAGTL----DGII 256 Query: 249 ECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGV-FRYCNTWPVA 307 + A + +S G L+LVG + +P + G Sbjct: 257 DTVSAVHPLLPLFGLLKSHGKLILVGAPEKPLELPAFSLIAGRKIVAGSGIGGMKETQEM 316 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFKK 340 I A ++ V + A E K Sbjct: 317 IDFAAKHNITADIEVIST---DYLNTAMERLAK 346 >3HZZ-A nrPDB Length = 467 Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats. Identities = 70/365 (19%), Positives = 126/365 (34%), Gaps = 48/365 (13%) Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYW------------EYGRIGNFIVKKPM- 66 + L+ P+PE GP E L+ + + + + V YG++ + + Sbjct: 76 IHLDEVPVPELGPGEALVAVMASSVNYNSVWTSIFEPVSTFAFLERYGKLSPLTKRHDLP 135 Query: 67 --VLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP 124 ++G + +G V + G V +PGD V + L P Sbjct: 136 YHIIGSDLAGVVLRTGPGVNAWQPGDEVVAHCLSVELESPD-GHDDTMLDPEQRIWGFET 194 Query: 125 DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR------GGVTLGHKVLV 178 + G L P ++T+EE A P V A R+ + G VL+ Sbjct: 195 NFGGLAEIALVKTNQLMPKPKHLTWEEAA--APGLVNSTAYRQLVSRNGAAMKQGDNVLI 252 Query: 179 CGA-GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQI-----------SK 226 GA G +G A A GA + V S + + +GA+ ++ Sbjct: 253 WGASGGLGSYATQFALAGGANPICVV-SSPQKAEICRSMGAEAIIDRNAEGYKFWKDEHT 311 Query: 227 ESPQEIA---RKVEGQLGCKP-EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSE-MTT 281 + P+E +++ G + ++ E G E + A +Y TR GG + S M Sbjct: 312 QDPKEWKRFGKRIRELTGGEDIDIVFEHPGRE-TFGASVYVTRKGGTITTCASTSGYMHE 370 Query: 282 VPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEA----FET 337 + + I G + N + + P ++ + LE+ +A Sbjct: 371 YDNRYLWMSLKRIIGS-HFANYREAYEANRLIAKGKIHPTLSKTYSLEETGQAAYDVHRN 429 Query: 338 FKKGL 342 +G Sbjct: 430 LHQGK 434 >4RVS-A nrPDB Length = 329 Score = 182 bits (463), Expect = 2e-46, Method: Composition-based stats. Identities = 88/349 (25%), Positives = 140/349 (40%), Gaps = 50/349 (14%) Query: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGT 75 GPG LR + P P+PG E+L++ ++G+ D ++ R G + + P V+G E GT Sbjct: 12 GPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYF----RSGQYPRELPFVIGSEVCGT 67 Query: 76 VEKVGSSV----KHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCR 131 VE VG V + GDRV + +G Sbjct: 68 VEAVGPGVTAADTAISVGDRVV----------------------------SASANGAYAE 99 Query: 132 FYKHNAAFCYKLPDNVTFEEG--ALIEPLSVGIHACRRGGVTLGHKVLV-CGAGPIGMVT 188 F A+ K+PD+VT E AL++ L+ V G VLV GAG +G++ Sbjct: 100 FCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLIL 159 Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248 A +G +V+ T +A + +K+ GAD+VL +++ Q R E G + Sbjct: 160 TQWATHLG-VRVITTVSTAEKAKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGVQAVY 218 Query: 249 ECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVP----LLHAAIREVDIKGVFRYCNT- 303 + GA + A + + G L L G S L A + +F + T Sbjct: 219 DGVGA-TTFDASLASLAVRGTLALFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTRTG 277 Query: 304 ----WPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 W A A + + V R+PL AL A + + + ++ Sbjct: 278 EEFSWRAAELFDAIGNEAITVAVGGRYPLADALRAHQDLEARKTVGSVV 326 >1WLY-A nrPDB Length = 333 Score = 182 bits (461), Expect = 3e-46, Method: Composition-based stats. Identities = 69/357 (19%), Positives = 135/357 (37%), Gaps = 49/357 (13%) Query: 10 LSLVVH---GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPM 66 ++ V+H GP + E + PGP +V LR ++G+ D ++ + + P+ Sbjct: 3 MAAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAGIPHPLVVGEPPI 62 Query: 67 VLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDD 126 V+G EA+ VE+VG V G+RV C P Sbjct: 63 VVGFEAAAVVEEVGPGVTDFTVGERV---------------------------CTCLPPL 95 Query: 127 GNLCRFYKHNAAFCYKLPDNVTFE----EGALIEPLSVGIHACRRGGVTLGHKVLV-CGA 181 G + + A K+P ++ + G +++ ++ + V G VL+ A Sbjct: 96 GAYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMTAQYLLHQTHKVKPGDYVLIHAAA 155 Query: 182 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLG 241 G +G + + A+ +GA V+ T + + A+++G + S + E+ R++ G G Sbjct: 156 GGMGHIMVPWARHLGA-TVIGTVSTEEKAETARKLGCHHTINYSTQDFAEVVREITGGKG 214 Query: 242 CKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSE--MTTVPLLHAAIRE---VDIKG 296 +V + G + ++Q + R G G S + +R + Sbjct: 215 --VDVVYDSIG-KDTLQKSLDCLRPRGMCAAYGHASGVADPIRVVEDLGVRGSLFITRPA 271 Query: 297 VFRY---CNTWPVAIS--MLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 ++ Y + A K+ + V FPL +A A + + ++ Sbjct: 272 LWHYMSNRSEIDEGSKCLFDAVKAGVLHSSVAKTFPLREAAAAHKYMGGRQTIGSIV 328 >4J6F-A nrPDB Length = 382 Score = 180 bits (457), Expect = 7e-46, Method: Composition-based stats. Identities = 69/372 (18%), Positives = 131/372 (35%), Gaps = 36/372 (9%) Query: 1 MAAAAKPNNLSLVVHGPGDLR----LENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYG- 55 M + ++++ G G L + P+P P EVL+++ + G+ +DV E Sbjct: 26 MMHSVPKTMTAVLLTGHGGLEKLVYSRDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAY 85 Query: 56 ------------RIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPREND 103 R + P + G + G + VG V + G+RV + Sbjct: 86 GTEDDPSAVSTWRRHGNTLTFPRIQGTDTVGHIVAVGEGVDRARIGERVMV--------- 136 Query: 104 EFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNV-TFEEGALIEPLSVGI 162 +F R + S + DG + A + + ++ E G Sbjct: 137 DFSIYNRDDDSLADIDYMGHGRDGGYAEYMALPAENAHVVATDLTDIELATFCCAYLTGE 196 Query: 163 HACRRGGVTLGHKVLVCGA-GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 221 R + G VLV GA G +G + +A+A GA + V + + +IGA V Sbjct: 197 RMLERARLAAGETVLVTGASGGVGSAIIQLARARGAVPIAVAG--PGKEAAMLDIGAQAV 254 Query: 222 LQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVG-LGSEMT 280 + + E G G +V + G + R G G + + Sbjct: 255 VTRGQGDLAEAVEAASG--GRPIDVVADLVGGP-LFNDLLKILRPEGRYTTAGAIAGPVV 311 Query: 281 TVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEA-FETFK 339 + L ++++++ G + + + ++PLV +PL + A + Sbjct: 312 QLDLRTMYLKQLELHGSSQGSRADFRRLVRYIEEK-KIRPLVGGVYPLSEFHRAQTDFMA 370 Query: 340 KGLGLKIMLKCD 351 K K+++ D Sbjct: 371 KNFVGKLVVVPD 382 >5H82-A nrPDB Length = 389 Score = 179 bits (454), Expect = 2e-45, Method: Composition-based stats. Identities = 69/346 (19%), Positives = 116/346 (33%), Gaps = 34/346 (9%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVE 77 G L + G ++V ++ G+C DV + K P V GHE G V Sbjct: 39 GLLSPFKFLRRTTGEHDVQFKVLYCGLCDWDVITTKN---TYGTTKYPFVPGHEIMGIVT 95 Query: 78 KVGSSVKHLKPGDRVAIEPGAP-RENDEFCKMGRYNLSPSIFFC-ATPPDD--------- 126 ++G+ VK K GD+V + E C G P + + T D Sbjct: 96 EIGNKVKKFKVGDKVGVGNFIGSCGKCERCNEGLEPYCPKVIYTDGTAFSDENNTVYGDV 155 Query: 127 ---------GNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLS-VGIHACRRGGV-TLGHK 175 G N ++ P+N+ G I V R G+ G Sbjct: 156 SGDGEDRIYGGYSNIMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLS 215 Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARK 235 + V G G IG + + AKA GA V++ + + ++ G D L + + A Sbjct: 216 IGVVGFGRIGKLAVKFAKAFGANVTVISTSISKKQEAIEKYGVDRFLISKEPEEMKAAES 275 Query: 236 VEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIK 295 + +C + + + + G V++G+ E +P+ + Sbjct: 276 T-------LDGIFDCVPSVHPLHPLLNLLKFEGTFVMLGVAVEAYELPVSPLLMGRRKFV 328 Query: 296 GVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 G + A+K V + P++ A E KG Sbjct: 329 GSISGTMKETQEMLDFAAKHNIVSDI--ELIPMDYVNTALERIAKG 372 >3JYN-A nrPDB Length = 325 Score = 178 bits (451), Expect = 4e-45, Method: Composition-based stats. Identities = 80/351 (22%), Positives = 131/351 (37%), Gaps = 51/351 (14%) Query: 13 VVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEA 72 V GP L ++ PGP V++R ++G+ D +Y F P LG E Sbjct: 9 TVGGPEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPF---LPSGLGAEG 65 Query: 73 SGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRF 132 +G VE VG V K GDRVA G G Sbjct: 66 AGVVEAVGDEVTRFKVGDRVAYGTG---------------------------PLGAYSEV 98 Query: 133 YKHNAAFCYKLPDNVTFEEGA--LIEPLSVGIHACRRGGVTLGHKVLV-CGAGPIGMVTL 189 + A KL D+V+FE+ A +++ L+V + V G +L AG +G + Sbjct: 99 HVLPEANLVKLADSVSFEQAAALMLKGLTVQYLLRQTYQVKPGEIILFHAAAGGVGSLAC 158 Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249 AKA+GA +++ T S + + AK +GA + S E + ++ G K V + Sbjct: 159 QWAKALGA-KLIGTVSSPEKAAHAKALGAWETIDYSHEDVAKRVLELTD--GKKCPVVYD 215 Query: 250 CTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDI------KGVFRYCNT 303 G + + + + G +V G S + L ++ + G + Sbjct: 216 GVG-QDTWLTSLDSVAPRGLVVSFGNASGPVSGVNLGILAQKDSVYVTRPTLGSYANNAQ 274 Query: 304 W-----PVAISMLASKSVNVKPLVTHRFPLEKALEA-FETFKKGLGLKIML 348 MLAS + V + ++ L+ A +A E + +L Sbjct: 275 NLQTMADELFDMLASGKLKVDGI--EQYALKDAAKAQIELSARRTTGSTIL 323 >5Z0C-A nrPDB Length = 374 Score = 178 bits (451), Expect = 4e-45, Method: Composition-based stats. Identities = 69/333 (20%), Positives = 116/333 (34%), Gaps = 23/333 (6%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVE 77 G L + G +V ++ GIC SD+HY + P + GHE G V Sbjct: 24 GHLSPFTFSRRATGELDVTFKVLYCGICHSDLHYIKNEWSNTI---YPALPGHEIVGEVT 80 Query: 78 KVGSSVKHLKPGDRVAIEPGAP-RENDEFCKMGRYNLSPSI------FFCATPPDDGNLC 130 +VGS V K GD+V + + C N P+ + + G Sbjct: 81 EVGSKVNKFKVGDKVGVGCIVGSCHSCPNCNNHLENYCPNRILTFGSRYYDGTLNHGGYS 140 Query: 131 RFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGHKVLVCGAGPIGMVT 188 F ++PD + + A + + +++ R G G V V G G +G + Sbjct: 141 DLMVVQEHFAVRIPDALPLDSAAPLLCAGITVYSPLRYYGLDKPGLHVGVVGLGGLGHMA 200 Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248 + AKA G VV+ A + +GA + + E + G + + I Sbjct: 201 VKFAKAFGVKVTVVSTSPAKKEDAISGLGAHSFILSTD---AEQMQAAVGTM----DGII 253 Query: 249 ECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGV-FRYCNTWPVA 307 + A + I +S G LV+VG + +P+ + + G Sbjct: 254 DTVSASHPLPPLISLLKSHGKLVMVGDPPKPLELPVFPLLLGRKMVAGSAIGGMKETQEM 313 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFKK 340 I A + V P++ A + K Sbjct: 314 IDFAAKEGVRAD---VEVIPMDYVNTAMQRVSK 343 >4OAQ-A nrPDB Length = 367 Score = 175 bits (445), Expect = 2e-44, Method: Composition-based stats. Identities = 70/361 (19%), Positives = 133/361 (36%), Gaps = 30/361 (8%) Query: 1 MAAAAKPNNLSLVVHGPGDL---RLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRI 57 M A V P + +L +Y + P++V+L+ G+C SD+H G Sbjct: 1 MTKAVPDKFQGFAVSDPKNWNRPKLASYERKQINPHDVVLKNEVCGLCYSDIHTLSAGW- 59 Query: 58 GNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRE---------NDEFCKM 108 + + +V+GHE G V VG V K GDRV I + N+++CK Sbjct: 60 -QPLQRDNLVVGHEIIGEVIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYCKQ 118 Query: 109 GRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHA--CR 166 G + G + F + +P+++ GA + + + + R Sbjct: 119 GAATYNSKDVRSNNYVTQGGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIR 178 Query: 167 RGGVTL-GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQIS 225 G+ G V + G G +G + L A AMGA V S+++ +A ++GA + Sbjct: 179 NLGLDARGKNVGIIGIGGLGHLALQFANAMGA-NVTAFSRSSSKKEQAMKLGAHDFVATG 237 Query: 226 KESPQEIARKVEGQLGCKPEVTIECTGAEA--SIQAGIYATRSGGNLVLVGLGSEMTTVP 283 ++ + + + C ++ + + V VGL Sbjct: 238 ED------KTWYKNYDDHFDFILNCASGIDGLNLSEYLSTLKVDKKFVSVGLPPSEDKFE 291 Query: 284 LLHAA-IREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKAL--EAFETFKK 340 + +++ G + V + + NV+P++ P+ + +A + Sbjct: 292 VSPFTFLQQGASFGSSLLGSKTEVKEMLNLAAKHNVRPMI-EEVPISEENCAKALDRCHA 350 Query: 341 G 341 G Sbjct: 351 G 351 >1Q1N-A nrPDB Length = 360 Score = 173 bits (439), Expect = 1e-43, Method: Composition-based stats. Identities = 77/330 (23%), Positives = 138/330 (41%), Gaps = 30/330 (9%) Query: 29 EPGP---NEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGS-SVK 84 +P P +++ +++ + G+CGSD+H G GN K P+V+GHE G V K+G S Sbjct: 27 DPKPFYDHDIDIKIEACGVCGSDIH-CAAGHWGNM--KMPLVVGHEIVGKVVKLGPKSNS 83 Query: 85 HLKPGDRVAIEPGA-PRENDEFCKMGRYNLSPS-IFFCATPPDD-----GNLCRFYKHNA 137 LK G RV + + CK + + P +D G + + + Sbjct: 84 GLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDGYVSQGGYANYVRVHE 143 Query: 138 AFCYKLPDNVTFEEGALIEPLSVGIHA-CRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMG 196 F +P+N+ A + + +++ R G G KV + G G IG + L++KAMG Sbjct: 144 HFVVPIPENIPSHLAAPLLCGGLTVYSPLVRNGCGPGKKVGIVGLGGIGSMGTLISKAMG 203 Query: 197 AAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEAS 256 A V S+ + A ++GAD + +E + K ++ + C + Sbjct: 204 AETY-VISRSSRKREDAMKMGADHYIATLEEG--DWGEKYFDTF----DLIVVCASSLTD 256 Query: 257 IQAGI--YATRSGGNLVLVGLGSEMTTVPLLHAAIREVDI-KGVFRYCNTWPVAISMLAS 313 I I A + GG +V + + + + L ++ V I + +++ Sbjct: 257 IDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPYGLKAVSISYSALGSIKELNQLLKLVSE 316 Query: 314 KSVNVKPLVTHRFPLEK--ALEAFETFKKG 341 K + + P+ + EAFE +KG Sbjct: 317 KDIKI---WVETLPVGEAGVHEAFERMEKG 343 >5FI5-A nrPDB Length = 357 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 67/326 (20%), Positives = 113/326 (34%), Gaps = 19/326 (5%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVE 77 G N+ G ++V L++ G C D E + P VLGHE G V Sbjct: 28 GLFSPFNFSRRATGEHDVQLKVLYCGTCQYD---REMSKNKFGFTSYPYVLGHEIVGEVT 84 Query: 78 KVGSSVKHLKPGDRVAIEPGA-PRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHN 136 +VGS V+ K GD+V + E C N P + G N Sbjct: 85 EVGSKVQKFKVGDKVGVASIIETCGKCEMCTNEVENYCPEAGSIDSNY--GACSNIAVIN 142 Query: 137 AAFCYKLPDNVTFEEGALIEPLSVGIHAC--RRGGVTLGHKVLVCGAGPIGMVTLLVAKA 194 F + P+N+ + G + + ++ R G G ++ + G G +G V L AKA Sbjct: 143 ENFVIRWPENLPLDSGVPLLCAGITAYSPMKRYGLDKPGKRIGIAGLGGLGHVALRFAKA 202 Query: 195 MGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAE 254 GA V++ + ++ GAD L S +P+E+ + I+ Sbjct: 203 FGAKVTVISSSLKKKREAFEKFGADSFLVSS--NPEEMQ-----GAAGTLDGIIDTIPGN 255 Query: 255 ASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYC-NTWPVAISMLAS 313 S++ + + G L+++G VP + + I A Sbjct: 256 HSLEPLLALLKPLGKLIILGAPEMPFEVPAPSLLMGGKVMAASTAGSMKEIQEMIEFAAE 315 Query: 314 KSVNVKPLVTHRFPLEKALEAFETFK 339 ++ ++ A E Sbjct: 316 HNIVAD---VEVISIDYVNTAMERLD 338 >3QWB-A nrPDB Length = 334 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 71/359 (19%), Positives = 136/359 (37%), Gaps = 49/359 (13%) Query: 7 PNNLSLV----VHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIV 62 P ++ + G ++ E+YP+P E+L++ G+ + Y R G + Sbjct: 6 PEQQKVILIDEIGGYDVIKYEDYPVPSISEEELLIKNKYTGVN----YIESYFRKGIYPC 61 Query: 63 KKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCAT 122 +KP VLG EASGTV G V + + GD+VA N F + + + + Sbjct: 62 EKPYVLGREASGTVVAKGKGVTNFEVGDQVAY-----ISNSTFAQYSKISSQGPVMKLPK 116 Query: 123 PPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKV-LVCGA 181 D + + L++ L+ V G V L A Sbjct: 117 GTSD------------------EELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFAAA 158 Query: 182 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLG 241 G +G++ + K GA + + +L AKE GA+ ++ SKE + + ++ G Sbjct: 159 GGVGLILNQLLKMKGAHT-IAVASTDEKLKIAKEYGAEYLINASKEDI--LRQVLKFTNG 215 Query: 242 CKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSE-MTTVPLLHAAIREVD-----IK 295 + + + G + + + + A + G V G S + + + + + + Sbjct: 216 KGVDASFDSVG-KDTFEISLAALKRKGVFVSFGNASGLIPPFSITRLSPKNITLVRPQLY 274 Query: 296 GVFRYCNTWPVAIS----MLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL-KIMLK 349 G W ++ SK +N+K + +PL A + + K++L+ Sbjct: 275 GYIADPEEWKYYSDEFFGLVNSKKLNIK--IYKTYPLRDYRTAAADIESRKTVGKLVLE 331 >1QOR-A nrPDB Length = 327 Score = 170 bits (432), Expect = 5e-43, Method: Composition-based stats. Identities = 77/339 (22%), Positives = 129/339 (38%), Gaps = 48/339 (14%) Query: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGT 75 GP L+ + +P NE+ + ++GI D + P LG EA+G Sbjct: 12 GPEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGL---YPPPSLPSGLGTEAAGI 68 Query: 76 VEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKH 135 V KVGS VKH+K GDRV A G + Sbjct: 69 VSKVGSGVKHIKAGDRVVYAQSA---------------------------LGAYSSVHNI 101 Query: 136 NAAFCYKLPDNVTFEEGA--LIEPLSVGIHACRRGGVTLGHKVLV-CGAGPIGMVTLLVA 192 A LP ++FE+ A ++ L+V + + + L AG +G++ A Sbjct: 102 IADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQWA 161 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTG 252 KA+GA +++ T +A + A + GA V+ +E E +++ G G K V + G Sbjct: 162 KALGA-KLIGTVGTAQKAQSALKAGAWQVINYREEDLVERLKEITG--GKKVRVVYDSVG 218 Query: 253 AEASIQAGIYATRSGGNLVLVGLGSEMTT-VPLLHAAIREV------DIKGVFRYCNTW- 304 + + + + + G +V G S T V L + ++G Sbjct: 219 RD-TWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREELT 277 Query: 305 ---PVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKK 340 S++AS + V ++PL+ A A E + Sbjct: 278 EASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILES 316 >6C49-A nrPDB Length = 350 Score = 167 bits (424), Expect = 5e-42, Method: Composition-based stats. Identities = 66/350 (18%), Positives = 123/350 (35%), Gaps = 18/350 (5%) Query: 9 NLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVL 68 + L + E P++V +++ G+C SD+ P+V Sbjct: 15 QAYAAMQAGEKLVPYKFDAGELQPHQVEVKVEYCGLCHSDISVLNNEWHSTV---YPVVA 71 Query: 69 GHEASGTVEKVGSSVKHLKPGDRVAIEPGA-PRENDEFCKMGRYNLSPSIFFCATPPDDG 127 GHE G + +GS K L+ G RV I A + + C G+ L G Sbjct: 72 GHEIIGRIVALGSEAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENIATIVGHAG 131 Query: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIH-ACRRGGVTLGHKVLVCGAGPIGM 186 + + LP+++ E + + + + + H V V G G +G Sbjct: 132 GFADKVRAGWQWAIPLPEDLDPESAGPLLCGGITVFDPLLKHKIQATHHVGVIGIGGLGH 191 Query: 187 VTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEV 246 + + + KA G ++ + + + K +GAD V+ + + K ++ Sbjct: 192 IAIKLLKAWG-CEITAFSSNPDKTEELKAMGADHVVNSRDTEAVKAQK-------GKFDL 243 Query: 247 TIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGV-FRYCNTWP 305 + + +A I G+L +GL E V + + G Sbjct: 244 LLSTVNVTLNWRAFISTLAPNGSLHFLGLTLEPVPVSVGSLIDGAKSVTGSPTGSPAALR 303 Query: 306 VAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL-KIMLKCDPSD 354 + A K + + FP+ + EA E G +I+LK D ++ Sbjct: 304 QLLKFAARKKIAPQ---IELFPMSQLNEAIERLHSGQARYRIVLKADFAE 350 >5VKT-A nrPDB Length = 362 Score = 166 bits (420), Expect = 2e-41, Method: Composition-based stats. Identities = 66/334 (19%), Positives = 116/334 (34%), Gaps = 23/334 (6%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVE 77 G L ++ G +V +++ GIC +D+H + GN + P+V GHE G V Sbjct: 20 GHLSPYSFSARIQGDADVTIKVLFCGICHTDLHVIK-NEWGNAM--YPVVPGHEVVGVVT 76 Query: 78 KVGSSVKHLKPGDRVAIEPGA-PRENDEFCKMGRYNLSPSIFFCATPPDD--------GN 128 VG V K GD V + E C G N P + + D G Sbjct: 77 DVGHGVTKFKAGDTVGVGYFVDSCRTCESCSTGHENYCPDLVLTSNGVDHHHHGATTKGG 136 Query: 129 LCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHA--CRRGGVTLGHKVLVCGAGPIGM 186 + F ++P+++ + A + V +++ + G + V G G +G Sbjct: 137 FSDVLVVSQDFVVRVPESLPLDGAAPLLCAGVTVYSPMAQYALNEPGKHLGVVGLGGLGH 196 Query: 187 VTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEV 246 + + AKA G V++ R +GAD L + + A + Sbjct: 197 MAVKFAKAFGMTVTVISSSPGKRDEALGRLGADAFLVSHDAAQMKAAAAT-------LDG 249 Query: 247 TIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPV 306 I+ A I + + G +V+VG S +P + G + Sbjct: 250 IIDTVSAGHQIVPLLALLKPMGQMVVVGAPSTPLELPAYAIITGGKRVAGN-GVGSVADC 308 Query: 307 AISMLASKSVNVKPLVTHRFPLEKALEAFETFKK 340 + + V + ++ A E +K Sbjct: 309 QAMLDFAGEHGVTADI-EVVQMDYVNTAIERLEK 341 >2DPH-A nrPDB Length = 398 Score = 163 bits (413), Expect = 9e-41, Method: Composition-based stats. Identities = 92/400 (23%), Positives = 154/400 (38%), Gaps = 73/400 (18%) Query: 9 NLSLVVHGPGDLRLENYPIPEPG------PNEVLLRMHSVGICGSDVHYWEYGRIGNFIV 62 N S+V HG DLR+E P P+ + V+L++ S ICGSD H + G FIV Sbjct: 3 NKSVVYHGTRDLRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSDQHIYR----GRFIV 58 Query: 63 KKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPS------ 116 K VLGHE +G V + GS V+ + GD V++ CK R ++ + Sbjct: 59 PKGHVLGHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCENNLVNPD 118 Query: 117 ----IFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEG--------ALIEPLSVGIHA 164 F G + A Y L E+ + + L G H Sbjct: 119 ADLGAFGFDLKGWSGGQAEYVLVPYAD-YMLLKFGDKEQAMEKIKDLTLISDILPTGFHG 177 Query: 165 CRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQI 224 C GV G V + GAGP+G A+ +GAA V+V D + RL + G + + + Sbjct: 178 CVSAGVKPGSHVYIAGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGFE-TIDL 236 Query: 225 SKESPQEIARKVEGQLGC-KPEVTIECTGAEA--------------SIQAGIYATRSGGN 269 +P + +++ LG + + ++ G EA ++ + R+GG Sbjct: 237 RNSAP--LRDQIDQILGKPEVDCGVDAVGFEAHGLGDEANTETPNGALNSLFDVVRAGGA 294 Query: 270 LVLVGL-------------GSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISM------ 310 + + G+ GS + + + I + ++ Sbjct: 295 IGIPGIYVGSDPDPVNKDAGSGRLHLDFGKMWTKSIRIMTGMAPVTNYNRHLTEAILWDQ 354 Query: 311 --LASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348 SK +N++ L++A + + F KG K ++ Sbjct: 355 MPYLSKVMNIE-----VITLDQAPDGYAKFDKGSPAKFVI 389 >4JLW-A nrPDB Length = 399 Score = 163 bits (412), Expect = 1e-40, Method: Composition-based stats. Identities = 87/394 (22%), Positives = 154/394 (39%), Gaps = 61/394 (15%) Query: 9 NLSLVVHGPGDLRLENYPIPEPGP-------NEVLLRMHSVGICGSDVHYWEYGRIGNFI 61 N +V GPG + ++N P P+ + V+LR+ S ICGSD H G Sbjct: 4 NRGVVYLGPGKVEVQNIPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVR----GRTT 59 Query: 62 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS------- 114 + +VLGHE +G V ++G V+ +K GD V++ + CK + Sbjct: 60 APEGLVLGHEITGEVVEIGRGVETMKIGDLVSVPFNVACGHCRTCKEQHTGVCLTVNPAR 119 Query: 115 --PSIFFCATPPDDGNLCRFYKHN--AAFCYKLP-DNVTFEEG----ALIEPLSVGIHAC 165 + + G + KLP E+ L + L G H Sbjct: 120 AGGAYGYVDMGGWVGGQAEYVLVPYADFNLLKLPNREAAMEKIRDLTCLSDILPTGYHGA 179 Query: 166 RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQIS 225 GV G V + GAGP+G+ A+ +GAA V+V D++ TRL+ AK+ G ++ +S Sbjct: 180 VTAGVGPGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQGFEIA-DLS 238 Query: 226 KESPQEIARKVEGQLGC-KPEVTIECTGAEA---------------SIQAGIYATRSGGN 269 K++P + ++ LG + + ++ G EA + + + TR G Sbjct: 239 KDTP--LHEQIAALLGEPEVDCAVDAVGFEARGHGHSGSQQEAPATVLNSLMGITRVAGK 296 Query: 270 LVLVGLGSEMTTVPLLHAAI-REVDIKGVFRYCNTW-------------PVAISMLASKS 315 + + GL + AA + I+ + + + + Sbjct: 297 IGIPGLYVTEDPGAVDAAAKHGALSIRFGLGWAKSHSFHTGQTPVMKYNRQLMQAIMWDR 356 Query: 316 VNVKPLVT-HRFPLEKALEAFETFKKGLGLKIML 348 + + +V L+ A + + F G+ K ++ Sbjct: 357 IKIADIVGVEVITLDDAPKGYGEFDAGVPKKFVI 390 >5H83-A nrPDB Length = 360 Score = 162 bits (411), Expect = 2e-40, Method: Composition-based stats. Identities = 68/328 (20%), Positives = 117/328 (35%), Gaps = 19/328 (5%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVE 77 G N+ G N+V ++ G C D+ + G + K P V+GHE G V Sbjct: 25 GFFSPFNFSRRATGENDVQFKVLYCGTCNYDLEM-STNKFG--MTKYPFVIGHEIVGVVT 81 Query: 78 KVGSSVKHLKPGDRVAIEPGAP-RENDEFCKMGRYNLSPSIFFCATPP--DDGNLCRFYK 134 ++GS V+ K GD+V + E E C G N + + G C Sbjct: 82 EIGSKVQKFKVGDKVGVGGFVGACEKCEMCVNGVENNCSKVESTDGHFGNNFGGCCNIMV 141 Query: 135 HNAAFCYKLPDNVTFEEGALIEPLSVGIHA--CRRGGVTLGHKVLVCGAGPIGMVTLLVA 192 N + P+N+ G + + ++ R G G + + G G +G + + A Sbjct: 142 VNEKYAVVWPENLPLHSGVPLLCAGITTYSPLRRYGLDKPGLNIGIAGLGGLGHLAIRFA 201 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTG 252 KA GA +++ + ++ G D L +P+E+ + I+ Sbjct: 202 KAFGAKVTLISSSVKKKREALEKFGVDSFL--LNSNPEEMQ-----GAYGTLDGIIDTMP 254 Query: 253 AEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYC-NTWPVAISML 311 SI + + G L+++G+ E VP + I G I Sbjct: 255 VAHSIVPFLALLKPLGKLIILGVPEEPFEVPAPALLMGGKLIAGSAAGSMKETQEMIDFA 314 Query: 312 ASKSVNVKPLVTHRFPLEKALEAFETFK 339 A ++ P++ A E K Sbjct: 315 AKHNIVAD---VEVIPIDYLNTAMERIK 339 >3TQH-A nrPDB Length = 321 Score = 155 bits (392), Expect = 3e-38, Method: Composition-based stats. Identities = 65/339 (19%), Positives = 124/339 (36%), Gaps = 52/339 (15%) Query: 13 VVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK-----PMV 67 P L+L + P PE N++L+++H+ + D ++ F+ KK P Sbjct: 14 QFGPPKVLKLVDTPTPEYRKNQMLIKVHAASLNPID---YKTRNGSGFVAKKLKNNLPSG 70 Query: 68 LGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDG 127 LG++ SG V ++GS V ++ GD+V G P C Sbjct: 71 LGYDFSGEVIELGSDVNNVNIGDKVMGIAGFPDHPC--C--------------------- 107 Query: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLS-VGIHACRRGGVTLGHKVLV-CGAGPIG 185 + + + + ++F + A + + A + V G VL+ GAG +G Sbjct: 108 -YAEYVCASPDTIIQKLEKLSFLQAASLPTAGLTALQALNQAEVKQGDVVLIHAGAGGVG 166 Query: 186 MVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPE 245 + + +AK G + T S + K +GA+ + +E + Sbjct: 167 HLAIQLAKQKGTTVI--TTASKRNHAFLKALGAEQCINYHEEDFLLAIS-------TPVD 217 Query: 246 VTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWP 305 I+ G + I I + G +V V + + + + G+ + + Sbjct: 218 AVIDLVGGDVGI-QSIDCLKETGCIVSVPTITAGRVIEVAKQ--KHRRAFGLLK---QFN 271 Query: 306 VAISMLASKSVNVKPL---VTHRFPLEKALEAFETFKKG 341 + K V+ L ++ F L +A+ A E + G Sbjct: 272 IEELHYLGKLVSEDKLRIEISRIFQLSEAVTAHELLETG 310 >1KOL-A nrPDB Length = 398 Score = 153 bits (387), Expect = 9e-38, Method: Composition-based stats. Identities = 86/394 (21%), Positives = 150/394 (38%), Gaps = 61/394 (15%) Query: 9 NLSLVVHGPGDLRLENYPIPEPG-------PNEVLLRMHSVGICGSDVHYWEYGRIGNFI 61 N +V G G + ++ P+ + V+L++ S ICGSD H G Sbjct: 3 NRGVVYLGSGKVEVQKIDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVR----GRTT 58 Query: 62 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS------- 114 + +VLGHE +G V + G V++L+ GD V++ CK + Sbjct: 59 AQVGLVLGHEITGEVIEKGRDVENLQIGDLVSVPFNVACGRCRSCKEMHTGVCLTVNPAR 118 Query: 115 --PSIFFCATPPDDGNLCRFYKHN--AAFCYKLPD-NVTFEEG----ALIEPLSVGIHAC 165 + + G + KLPD + E+ L + L G H Sbjct: 119 AGGAYGYVDMGDWTGGQAEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGA 178 Query: 166 RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQIS 225 GV G V V GAGP+G+ A+ +GAA V+V DL+ RL+ AK G ++ +S Sbjct: 179 VTAGVGPGSTVYVAGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFEIA-DLS 237 Query: 226 KESPQEIARKVEGQLGC-KPEVTIECTGAEA---------------SIQAGIYATRSGGN 269 ++P + ++ LG + + ++ G EA + + + TR G Sbjct: 238 LDTP--LHEQIAALLGEPEVDCAVDAVGFEARGHGHEGAKHEAPATVLNSLMQVTRVAGK 295 Query: 270 LVLVGLGSEMTTVPLLHAA-IREVDIKGVFRYCNTW-------------PVAISMLASKS 315 + + GL + AA I + I+ + + + + Sbjct: 296 IGIPGLYVTEDPGAVDAAAKIGSLSIRFGLGWAKSHSFHTGQTPVMKYNRALMQAIMWDR 355 Query: 316 VNVKPLVT-HRFPLEKALEAFETFKKGLGLKIML 348 +N+ +V L+ A + F G+ K ++ Sbjct: 356 INIAEVVGVQVISLDDAPRGYGEFDAGVPKKFVI 389 >2CDC-A nrPDB Length = 366 Score = 152 bits (383), Expect = 3e-37, Method: Composition-based stats. Identities = 80/380 (21%), Positives = 144/380 (37%), Gaps = 52/380 (13%) Query: 2 AAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGR--IGN 59 A KP N + V + +L++Y ++ +R GICG+D Sbjct: 3 AIIVKPPNAGVQVKDVDEKKLDSY-------GKIKIRTIYNGICGADREIVNGKLTLSTL 55 Query: 60 FIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFF 119 K +VLGHEA G VE+ S GD V C +GR + + F Sbjct: 56 PKGKDFLVLGHEAIGVVEE---SYHGFSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEF 112 Query: 120 C--ATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLS---------------VGI 162 DG + ++ + + K+P ++ + G L +PL+ V + Sbjct: 113 GEAGIHKMDGFMREWWYDDPKYLVKIPKSIE-DIGILAQPLADIEKSIEEILEVQKRVPV 171 Query: 163 HACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL 222 C G + KVLV G GPIG++ L+ + G + T + + V+ Sbjct: 172 WTCDDGTLNC-RKVLVVGTGPIGVLFTLLFRTYGLEVWMANRREPTEVEQT-------VI 223 Query: 223 QISKESPQEIARKVEGQLG--CKPEVTIECTGAEASIQAGIY-ATRSGGNLVLVGLGSEM 279 + +K + + + K +V I+ TGA+ +I + G L L G S Sbjct: 224 EETKTNYYNSSNGYDKLKDSVGKFDVIIDATGADVNILGNVIPLLGRNGVLGLFGF-STS 282 Query: 280 TTVPLLHAAIREV-----DIKGVFRYCNTW--PVAISMLASKSVNVKP---LVTHRFPLE 329 +VPL + ++E+ I G+ + + + K++ K L+T + Sbjct: 283 GSVPLDYKTLQEIVHTNKTIIGLVNGQKPHFQQAVVHLASWKTLYPKAAKMLITKTVSIN 342 Query: 330 KALEAFETFKKGLGLKIMLK 349 E + ++ +I ++ Sbjct: 343 DEKELLKVLREKEHGEIKIR 362 >2VN8-A nrPDB Length = 375 Score = 147 bits (371), Expect = 7e-36, Method: Composition-based stats. Identities = 77/358 (21%), Positives = 139/358 (38%), Gaps = 76/358 (21%) Query: 32 PNEVLLRMHSVGICGSDVHYWE-YGRIGNFIVKKPM-----------VLGHEASGTVEKV 79 PNEV++++H+ + DV+ YG + + P+ LG + SG V + Sbjct: 50 PNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMEC 109 Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP-DDGNLCRFYKHNAA 138 G VK+ KPGD V + A PP G L F + Sbjct: 110 GLDVKYFKPGDEV--------------------------WAAVPPWKQGTLSEFVVVSGN 143 Query: 139 FCYKLPDNVTFEEGALIEPLSVGIHAC--RRGGVT----LGHKVLVCGA-GPIGMVTLLV 191 P ++T + A + +++ + + GG+ G +VL+ GA G +G + V Sbjct: 144 EVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQV 203 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECT 251 KA A V A+ +++GAD V+ S +E + ++ + ++ Sbjct: 204 MKAWDAHVTAVCSQDAS--ELVRKLGADDVIDYKSGSVEEQLKSLK-----PFDFILDNV 256 Query: 252 GAEASIQAGIYATRSGG------------NLVLVGLGSEM--TTVPLLHAAIREVDIKGV 297 G A + + G N+ +G+ M T V + A++ KGV Sbjct: 257 GGSTETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHF-WKGV 315 Query: 298 FRYCNTWPVA----ISMLAS--KSVNVKPLVTHRFPLEKALEAFETFKKGLG-LKIML 348 Y + +A + +A + ++P++ FP K EAF ++G K ++ Sbjct: 316 -HYRWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 372 >4EYE-A nrPDB Length = 342 Score = 147 bits (370), Expect = 9e-36, Method: Composition-based stats. Identities = 81/349 (23%), Positives = 130/349 (37%), Gaps = 52/349 (14%) Query: 14 VHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEAS 73 + GP L + P GPN V++ + + G+C D + ++ P V G E + Sbjct: 30 LSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGEY--QLKMEPPFVPGIETA 87 Query: 74 GTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFY 133 G V +KPGDRV G Sbjct: 88 GVVRSAPEG-SGIKPGDRVMAFNFI----------------------------GGYAERV 118 Query: 134 KHNAAFCYKLPDNVTFEEG-ALIEPLSVGIHA-CRRGGVTLGHKVLVC-GAGPIGMVTLL 190 + P + E ALI A RRG + G VLV AG IG + Sbjct: 119 AVAPSNILPTPPQLDDAEAVALIANYHTMYFAYARRGQLRAGETVLVLGAAGGIGTAAIQ 178 Query: 191 VAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIEC 250 +AK MGA + V + +A K +GAD+VL + +E + R+ G G ++ ++ Sbjct: 179 IAKGMGAKVIAVVNRTAAT-EFVKSVGADIVLPL-EEGWAKAVREATG--GAGVDMVVDP 234 Query: 251 TGAEASIQAGIYATRSGGNLVLVGL-GSEMTTVPLLHAAIREVDIKGV---------FRY 300 G A + S G L++VG + T+ + +R + GV Y Sbjct: 235 IGGPA-FDDAVRTLASEGRLLVVGFAAGGIPTIKVNRLLLRNASLIGVAWGEFLRTHADY 293 Query: 301 CNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL-GLKIML 348 + L ++ ++P V+ R PL + +A + F G K++L Sbjct: 294 LYETQAGLEKLVAEG--MRPPVSARIPLSEGRQALQDFADGKVYGKMVL 340 >3FBG-A nrPDB Length = 346 Score = 145 bits (365), Expect = 4e-35, Method: Composition-based stats. Identities = 60/344 (17%), Positives = 116/344 (33%), Gaps = 58/344 (16%) Query: 14 VHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEAS 73 + + N IPEP +E+L+++ S+ + D + K P VLG +A Sbjct: 14 LSDGNLFKTFNLDIPEPKVHEILVKIQSISVNPVDTKQRLMD-----VSKAPRVLGFDAI 68 Query: 74 GTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFY 133 G VE VG+ V GD V ++ +P +G+ + Sbjct: 69 GVVESVGNEVTMFNQGDIV-------------------------YYSGSPDQNGSNAEYQ 103 Query: 134 KHNAAFCYKLPDNVTFEEGALIEPLSVGIHA--------CRRGGVTLGHKVLVC-GAGPI 184 N K P N++ E+ + + + R G +L+ GAG + Sbjct: 104 LINERLVAKAPKNISAEQAVSLPLTGITAYETLFDVFGISRNRNENEGKTLLIINGAGGV 163 Query: 185 GMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 G + +AKA G +V+ T + K++GAD+VL + + + + Q Sbjct: 164 GSIATQIAKAYGL-RVITTASRNETIEWTKKMGADIVLNHKE----SLLNQFKTQGIELV 218 Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTW 304 + + I + G++ + A++ + + Sbjct: 219 DYVFCTFNTDMYYDDMIQLVKPRGHIATI----VAFENDQDLNALKPKSLSFSHEF---- 270 Query: 305 PVAISMLASKSVNVKPLVTHRFPLEKA-LEAFETFKKGLGLKIM 347 M A ++ H LE + + + K++ Sbjct: 271 -----MFARPLNQTDDMIKHHEYLEDITNKVEQNIYQPTTTKVI 309 >2VWH-A nrPDB Length = 357 Score = 144 bits (364), Expect = 5e-35, Method: Composition-based stats. Identities = 77/348 (22%), Positives = 129/348 (37%), Gaps = 31/348 (8%) Query: 12 LVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHE 71 V G + P PEP E L+R VG+ G+D G G + +VLGHE Sbjct: 5 AVKRGEDRPVVIEKPRPEPESGEALVRTLRVGVDGTDHEVIAGGHGGFPEGEDHLVLGHE 64 Query: 72 ASGTVEKVGSSVKHLKPGDRVA--IEPGAPRENDEFCKMGRYNLSPSIFFC--ATPPDDG 127 A G V V + L+ GD V + +E+ + + +++P + G Sbjct: 65 AVGVV--VDPNDTELEEGDIVVPTVRRPPASGTNEYFERDQPDMAPDGMYFERGIVGAHG 122 Query: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVG------IHACRRGGVTLGHKVLVCGA 181 + F+ + ++P + E G LIEP+S+ +A R V G Sbjct: 123 YMSEFFTSPEKYLVRIPRSQA-ELGFLIEPISITEKALEHAYASRSAFDWDPSSAFVLGN 181 Query: 182 GPIGMVTLLVAKA--MGAAQVVVTDLSAT---RLSKAKEIGADLVLQISKESPQEIARKV 236 G +G++TL + K G + + +E+ A V S+++P E V Sbjct: 182 GSLGLLTLAMLKVDDKGYENLYCLGRRDRPDPTIDIIEELDATYV--DSRQTPVEDVPDV 239 Query: 237 EGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSE-MTTVPLL----HAAIRE 291 Q+ + E TG + A G L+G+ S+ V + Sbjct: 240 YEQM----DFIYEATGFPKHAIQSVQALAPNGVGALLGVPSDWAFEVDAGAFHREMVLHN 295 Query: 292 VDIKGVFRYCNTWPVAISMLASKSVN--VKPLVTHRFPLEKALEAFET 337 + G A ++ +K ++ LVT PL + AF+ Sbjct: 296 KALVGSVNSHVEHFEAATVTFTKLPKWFLEDLVTGVHPLSEFEAAFDD 343 >2CF5-A nrPDB Length = 357 Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats. Identities = 68/333 (20%), Positives = 124/333 (37%), Gaps = 23/333 (6%) Query: 18 GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVE 77 G L Y + E GP +V +R+ GIC +D+H + + PMV GHE G V Sbjct: 20 GILSPYTYTLRETGPEDVNIRIICCGICHTDLHQTKND---LGMSNYPMVPGHEVVGEVV 76 Query: 78 KVGSSVKHLKPGD-RVAIEPGAPRENDEFCKMGRYNLSPSIFFC------ATPPDDGNLC 130 +VGS V GD C+ P + P G Sbjct: 77 EVGSDVSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIWSYNDVYINGQPTQGGFA 136 Query: 131 RFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHA--CRRGGVTLGHKVLVCGAGPIGMVT 188 + + F K+P+ + E+ A + V +++ G G + + G G +G + Sbjct: 137 KATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGGILGLGGVGHMG 196 Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGA-DLVLQISKESPQEIARKVEGQLGCKPEVT 247 + +AKAMG V++ + R +++GA D V+ + E+A + + Sbjct: 197 VKIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSDQAKMSELADSL--------DYV 248 Query: 248 IECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVA 307 I+ +++ + + G L+L+G+ + + I G F Sbjct: 249 IDTVPVHHALEPYLSLLKLDGKLILMGVINNPLQFLTPLLMLGRKVITGSFIGSMK-ETE 307 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFKK 340 + K + ++ ++ AFE +K Sbjct: 308 EMLEFCKEKGLSSII-EVVKMDYVNTAFERLEK 339 >4Y1B-A nrPDB Length = 425 Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats. Identities = 69/364 (18%), Positives = 134/364 (36%), Gaps = 44/364 (12%) Query: 15 HGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHY-------WEYGRIGNFIVKKPMV 67 R E +P GP +VL+++ + G+ ++V R + + Sbjct: 53 RPVDAFRTEVVDVPPVGPGQVLVKVMAAGVNYNNVWAALGEPLDVIAARQKQGATEDFHI 112 Query: 68 LGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNL-SPSIFFCATPPDD 126 G + SG V VG V LKPG V + E+ + ++G + S + + Sbjct: 113 GGSDLSGIVWAVGDGV-RLKPGAEVVVLACRWDESAQDIRLGADPVTSSTQRVWGYEENY 171 Query: 127 GNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR------GGVTLGHKVLVCG 180 G+ +F + C+ P +++ A ++ A R+ V G VL+ G Sbjct: 172 GSFAQFAVVDEYMCHPKPQRLSW--AAASCYMATAATAYRQLFGWEPHTVRPGDPVLIWG 229 Query: 181 -AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK---------ESPQ 230 AG +G + + + + +G V V S R +GA + + + + Sbjct: 230 GAGGLGSIAIQLVRHVGGIPVAVV-SSEERGEFCMRLGAKGWIDRREFDHWGRLPDTTDE 288 Query: 231 EIARK-VEGQLGCK------------PEVTIECTGAEASIQAGIYATRSGGNLVLV-GLG 276 E ++ ++G P + +E +GA+ +I IY + G +V+ G Sbjct: 289 EAMKQWLDGARAFGRRFWEVLGERRAPRIVLEHSGAD-TIPTSIYMADNAGMVVICGGTT 347 Query: 277 SEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFE 336 V L +R+ ++G I+ L + + P ++ F E+ A + Sbjct: 348 GYNGDVDLRFLWMRQKRLQGSHAASAREAREITRLIDQG-AIDPCLSRTFGFEEIGLAHQ 406 Query: 337 TFKK 340 Sbjct: 407 LIHD 410 >2OBY-A nrPDB Length = 338 Score = 137 bits (345), Expect = 7e-33, Method: Composition-based stats. Identities = 68/355 (19%), Positives = 122/355 (34%), Gaps = 57/355 (16%) Query: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPM--VLGHEAS 73 GP +L ++ P PG EVLL++ + + +D+ R G + +LG EAS Sbjct: 17 GPENLYVKEVAKPSPGEGEVLLKVAASALNRADL----MQRQGQYDPPPGASNILGLEAS 72 Query: 74 GTVEKVGSSVK-HLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRF 132 G V ++G + H K GD G ++ Sbjct: 73 GHVAELGPGCQGHWKIGDTAMALLP----------------------------GGGQAQY 104 Query: 133 YKHNAAFCYKLPDNVTFEEGALI-EPLSVGIHACRR-GGVTLGHKVLV-CGAGPIGMVTL 189 +P+ +T + A I E G V G VL+ G +G + Sbjct: 105 VTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAI 164 Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249 + + GA +VT S +L A+++GA KE E ++ G + ++ Sbjct: 165 QLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEA--TLKFTKGAGVNLILD 221 Query: 250 CTGAEASIQAGIYATRSGGNLVLVG-LGSEMTTVPLLHAAI-REVDIKGV---------- 297 C G + + + G VL G +G PL + + + Sbjct: 222 CIGG-SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYK 280 Query: 298 --FRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL-KIMLK 349 T + + P++ +P+ + EA + + + KI+L+ Sbjct: 281 QMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLE 335 >4IDE-A nrPDB Length = 332 Score = 135 bits (341), Expect = 2e-32, Method: Composition-based stats. Identities = 65/329 (19%), Positives = 119/329 (36%), Gaps = 47/329 (14%) Query: 24 NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSV 83 + +PE ++VL+++ + + D G + P + G++ +G V KVGS V Sbjct: 44 SVAVPEIKEDQVLIKVVAASLNPVDFK-RALGYFKDTDSPLPTIPGYDVAGVVVKVGSQV 102 Query: 84 KHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKL 143 K GD V + + P G+L + + Sbjct: 103 TKFKVGDEVYGDL-------------------NETALVNPTRFGSLAEYTAADERVLAHK 143 Query: 144 PDNVTFEEGALI-EPLSVGIHACRRGGVTLGHKVLVCGAGPIGMV-TLLVAKA-MGAAQV 200 P N++F E A + + R ++ G VLV G + +AK GA++V Sbjct: 144 PKNLSFIEAASLPLAIETAHEGLERAELSAGKSVLVLGGAGGVGTHIIQLAKHVFGASKV 203 Query: 201 VVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAG 260 T + +L + +GADL + +KE+ +++ K +V + G Sbjct: 204 AATASTK-KLDLLRTLGADLAIDYTKENFEDLPEK--------FDVVYDAVG---ETDKA 251 Query: 261 IYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKP 320 + A + GG +V + +G L + + L S V Sbjct: 252 VKAVKEGGKVVTI-VGPATPPAILFVLTSKG----------SVLEKLKPYLESGKVKPVL 300 Query: 321 LVTHRFPLEKALEAFETFKKGLG-LKIML 348 T +P K +EAF + K+++ Sbjct: 301 DPTSPYPFTKVVEAFGYLESSRATGKVVV 329 >4DVJ-A nrPDB Length = 363 Score = 130 bits (326), Expect = 1e-30, Method: Composition-based stats. Identities = 57/349 (16%), Positives = 105/349 (30%), Gaps = 58/349 (16%) Query: 24 NYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSV 83 P P P +++L+ + +V + D K V+G++A+G V VG V Sbjct: 44 ELPKPAPAGHDILVEVKAVSVNPVDYKVRRSTPPDGTDWK---VIGYDAAGIVSAVGPDV 100 Query: 84 KHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKL 143 +PGD V F+ + G F+ + + Sbjct: 101 TLFRPGDEV-------------------------FYAGSIIRPGTNAEFHLVDERIVGRK 135 Query: 144 PDNVTFEEGALIEPLSVGIHAC-----RRGGVTLGHKVLVC---GAGPIGMVTLLVAKAM 195 P + + E A + S+ G + GAG +G + + +A+ Sbjct: 136 PKTLDWAEAAALPLTSITAWEAFFDRLDVNKPVPGAAPAILIVGGAGGVGSIAVQIARQR 195 Query: 196 GAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEA 255 V+ T K +GA V+ SK +A +V P T + Sbjct: 196 TDLTVIATASRPETQEWVKSLGAHHVIDHSKP----LAAEVAALGLGAPAFVFSTTHTDK 251 Query: 256 SIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKS 315 G L+ + + ++ + V I + M Sbjct: 252 HAAEIADLIAPQGRFCLI---DDPSAFDIMLFKRKAVSIHHELMFTRPMFGTPDMSEQGR 308 Query: 316 V--NVKPLV-------THRFPLEKAL-----EAFETFKKGLG-LKIMLK 349 + +V LV T L +A + G K++++ Sbjct: 309 LLNDVSRLVDEGRLRTTLTNRLSPINAANLKQAHALVESGTARGKVVIE 357 >4A27-A nrPDB Length = 349 Score = 126 bits (316), Expect = 2e-29, Method: Composition-based stats. Identities = 68/374 (18%), Positives = 116/374 (31%), Gaps = 84/374 (22%) Query: 14 VHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEAS 73 G LRL +PEP E+ +R+ + G+ D+ + + K P+V G E S Sbjct: 12 FGGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNI--DNPPKTPLVPGFECS 69 Query: 74 GTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFY 133 G VE +G SVK + GDRV N + Sbjct: 70 GIVEALGDSVKGYEIGDRVM---------------AFVNYNAW-------------AEVV 101 Query: 134 KHNAAFCYKLPDNVTFEEGALIEPLSVGIHAC--RRGGVTLGHKVLVCGA-GPIGMVTLL 190 F YK+PD+++F E A V + + G VLV A G +G Sbjct: 102 CTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSAGGGVGQAVAQ 161 Query: 191 VAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIEC 250 + + V T + + K+ + + + QE+ R ++ ++C Sbjct: 162 LCSTVPNVTVFGTAST-FKHEAIKDS-VTHLFDRNADYVQEVKR----ISAEGVDIVLDC 215 Query: 251 TGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVA--I 308 + + G+ + G +L G + I Sbjct: 216 LCGDNT-GKGLSLLKPLGTYILYGSS--------NMVTGETKSFFSFAKSWWQVEKVNPI 266 Query: 309 SMLASKSV---------------------------------NVKPLVTHRFPLEKALEAF 335 + V +KP+V + LE+ EA Sbjct: 267 KLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKEAM 326 Query: 336 ETFK-KGLGLKIML 348 + +G K++L Sbjct: 327 QRIHDRGNIGKLIL 340 >5A3V-A nrPDB Length = 329 Score = 125 bits (315), Expect = 2e-29, Method: Composition-based stats. Identities = 59/343 (17%), Positives = 109/343 (31%), Gaps = 40/343 (11%) Query: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGT 75 G L P+P P NEV L++ + + D + K P + + +G Sbjct: 17 GAAGLEHVQVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGE 76 Query: 76 VEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKH 135 V +VGS VK+ K GD+V + G L F Sbjct: 77 VVEVGSGVKNFKAGDKVVA-------------------------VLSHLGGGGLAEFAVA 111 Query: 136 NAAFCYKLPDN--------VTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMV 187 K P + ++ L+ G + ++ +G +G Sbjct: 112 TEKLTVKRPQEVGAAEAAALPVAGLTALQALTNPAGLKLDGTGKKANILVTAASGGVGHY 171 Query: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVT 247 + +AK A A + K +GAD VL ++ G K + Sbjct: 172 AVQLAKLANAHVTATCG--ARNIEFVKSLGADEVLDYKTPEGA----ALKSPSGKKYDAV 225 Query: 248 IECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVA 307 + C + +G + + + M T + + + + + + Sbjct: 226 VHCANGIPFSVFEPNLSENGKVIDITPGPNAMWTYAVKKITMSKKQLVPLLLIPKAENLE 285 Query: 308 ISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG-LGLKIMLK 349 + K VK ++ + PL KA +A+ G KI+++ Sbjct: 286 FMVNLVKEGKVKTVIDSKHPLSKAEDAWAKSIDGHATGKIIVE 328 >3B70-A nrPDB Length = 371 Score = 120 bits (300), Expect = 1e-27, Method: Composition-based stats. Identities = 71/376 (18%), Positives = 117/376 (31%), Gaps = 75/376 (19%) Query: 7 PNNLSLVVHGPGDLRLENY-PIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKP 65 P +L V+ ++ + N P P ++V +R+ +V I SD G F Sbjct: 10 PQQTALTVNDHDEVTVWNAAPCPMLPRDQVYVRVEAVAINPSDTKMR-----GQFATPWA 64 Query: 66 MVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD 125 LG + +GTV VGS V H++ GDRV C PD Sbjct: 65 F-LGTDYAGTVVAVGSDVTHIQVGDRV--------------------YGAQNEMCPRTPD 103 Query: 126 DGNLCRFYKHNAAFCYKLPDNVTFEEGALI-EPLSVGIHACRRGGVTLGH---------- 174 G ++ K+P ++FE+ A + +S A + G+ L Sbjct: 104 QGAFSQYTVTRGRVWAKIPKGLSFEQAAALPAGISTAGLAMKLLGLPLPSPSADQPPTHS 163 Query: 175 ---KVLVCGAGPIGMVTL-----LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK 226 VLV G G + + G + S AK GA+ V Sbjct: 164 KPVYVLVYG----GSTATATVTMQMLRLSGYIPIATC--SPHNFDLAKSRGAEEVFDYRA 217 Query: 227 ESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYAT-RSGGNLVLVGLGSEMTTVPLL 285 + + R ++C S A R+GG+ V + E + Sbjct: 218 PNLAQTIRTYTKN---NLRYALDCITNVESTTFCFAAIGRAGGHYVSLNPFPEHAATRKM 274 Query: 286 HAAIREV--DIKGVFRYC-----------------NTWPVAISMLASKSVNVKPLVTHRF 326 + I G + W +A ++ + PL + Sbjct: 275 VTTDWTLGPTIFGEGSTWPAPYGRPGSEEERQFGEDLWRIAGQLVEDGRLVHHPLRVVQG 334 Query: 327 PLEKALEAFETFKKGL 342 + + E +KG Sbjct: 335 GFDHIKQGMELVRKGE 350 >2WEK-A nrPDB Length = 341 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 60/275 (21%), Positives = 104/275 (37%), Gaps = 41/275 (14%) Query: 23 ENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSS 82 + P+P PG ++L+R VG+ SD++Y GR + VK P +G E G V +G S Sbjct: 23 RDCPVPLPGDGDLLVRNRFVGVNASDINY-SAGRY-DPSVKPPFDIGFEGIGEVVALGLS 80 Query: 83 VK-HLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCY 141 G VA G+ + A+ Sbjct: 81 ASARYTVGQAVAYMAP-----------------------------GSFAEYTVVPASIAT 111 Query: 142 KLPDNVTFEEGALIEPLSVGIHACR-RGGVTLGHKVLV-CGAGPIGMVTLLVAKAMGAAQ 199 +P +V E L+ + + + GG++ G KVLV AG G + ++K Sbjct: 112 PVP-SVKPEYLTLLVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKA-KCH 169 Query: 200 VVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQA 259 V+ T S + + K +G D + E + ++ + +V E G A Sbjct: 170 VIGTCSSDEKSAFLKSLGCDRPINYKTEPVGTVLKQ---EYPEGVDVVYESVGG-AMFDL 225 Query: 260 GIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDI 294 + A + G L+++G S T P + ++ + Sbjct: 226 AVDALATKGRLIVIGFISGYQT-PTGLSPVKAGTL 259 >2VCY-A nrPDB Length = 344 Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats. Identities = 61/371 (16%), Positives = 131/371 (35%), Gaps = 54/371 (14%) Query: 2 AAAAKPNNLSLVVHGPG-----DLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGR 56 +A+A+P + +V+G + L+N + ++V ++M + I SD++ + Sbjct: 6 SASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNY 65 Query: 57 IGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPS 116 + + P V G+E V VGS+V LKPGD V Sbjct: 66 --GLLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVI----------------------- 100 Query: 117 IFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGH 174 G + ++P ++ + A + + + G Sbjct: 101 ----PANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGD 156 Query: 175 KVLVCGA-GPIGMVTLLVAKAMGAAQVVVTDLSAT--RL-SKAKEIGADLVLQISKESPQ 230 V+ + +G + +A A+G + V +L + K +GA+ V+ + Sbjct: 157 SVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRP 216 Query: 231 EIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLV-GLGSEMTTVPLLHAAI 289 E+ + +P + + C G ++S + + GG +V G+ + + Sbjct: 217 EMKNFFKDM--PQPRLALNCVGGKSSTE-LLRQLARGGTMVTYGGMAKQPVVASVSLLIF 273 Query: 290 REVDIKGVF-------RYCNTWPVAISML--ASKSVNVKPLVTHRFPLEKALEAFET-FK 339 +++ ++G + + + I L + + + PL+ A E K Sbjct: 274 KDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEASMK 333 Query: 340 KGLGLKIMLKC 350 + K +L Sbjct: 334 PFISSKQILTM 344 >3SLK-A nrPDB Length = 795 Score = 102 bits (253), Expect = 4e-22, Method: Composition-based stats. Identities = 66/348 (18%), Positives = 109/348 (31%), Gaps = 57/348 (16%) Query: 18 GDLRLENYPIP--EPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGT 75 L L + P G EV + M + G+ D G LG E +G Sbjct: 222 DGLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALGMYPGVAS------LGSEGAGV 275 Query: 76 VEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKH 135 V + G V L PGDRV P G L Sbjct: 276 VVETGPGVTGLAPGDRVMG--------------------------MIPKAFGPLA---VA 306 Query: 136 NAAFCYKLPDNVTFEEGA--LIEPLSVGIHACRRGGVTLGHKVLV-CGAGPIGMVTLLVA 192 + ++P +F A I L+ G+ G +LV AG +GM + +A Sbjct: 307 DHRMVTRIPAGWSFARAASVPIVFLTAYYALVDLAGLRPGESLLVHSAAGGVGMAAIQLA 366 Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTG 252 + +GA S + A E+ + + ++ G G +V + Sbjct: 367 RHLGAEVYA--TASEDKWQ-AVELSREHLASSRTCDFEQQFLGATG--GRGVDVVLNSLA 421 Query: 253 AEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHA-------AIREVDIKGVFRYCNTWP 305 E A + GG + +G V + A A V+ G R Sbjct: 422 GE-FADASLRMLPRGGRFLELGKTDVRDPVEVADAHPGVSYQAFDTVEA-GPQRIGEMLH 479 Query: 306 VAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL-KIMLKCDP 352 + + + + P+ + + +A EA + + K++L P Sbjct: 480 ELVELFEGRVLEPLPV--TAWDVRQAPEALRHLSQARHVGKLVLTMPP 525 >3WID-A nrPDB Length = 369 Score = 95.8 bits (237), Expect = 3e-20, Method: Composition-based stats. Identities = 72/371 (19%), Positives = 129/371 (34%), Gaps = 49/371 (13%) Query: 11 SLVVHGP-GDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMV 67 ++V P G ++ +PEP E L+ +GICG+D + + +V Sbjct: 6 AIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLV 65 Query: 68 LGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS----PSIFFCATP 123 LGHEA V V S ++K GD V P C++GR + P Sbjct: 66 LGHEALLQVLDV-SDNNYIKRGDFVVPLVRRP-GKCVNCRIGRQDNCSIGDPDKHEAGIT 123 Query: 124 PDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVT------------ 171 G + + K+ D + L EPL + A V Sbjct: 124 GLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDST 183 Query: 172 -LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVT--DLSATRLSKAKEIGADLVLQISKES 228 +G K++V G+G + V K G +V D + ++ + G K+ Sbjct: 184 FIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDETENKMKMMDDFGV-GFSNYLKDM 242 Query: 229 PQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLH-- 286 P +I ++ ++ +G ++I + + G ++L G + P+ Sbjct: 243 PDKI------------DLLVDTSGDPSTIFKFVKKVNNNGVVILFGFNGKAPGYPVNGED 290 Query: 287 ---AAIREVDIKGV-----FRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETF 338 R + I G Y + +K ++T+ E+ F+ Sbjct: 291 IDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKPEETNIFFQK- 349 Query: 339 KKGLGLKIMLK 349 KG +K ++K Sbjct: 350 PKGE-IKTVIK 359 >5LB9-A nrPDB Length = 385 Score = 88.9 bits (219), Expect = 3e-18, Method: Composition-based stats. Identities = 61/347 (17%), Positives = 114/347 (32%), Gaps = 48/347 (13%) Query: 32 PNEVLLRMHSVGICGSDVHYWEY------GRIGNFIVKKPMVL-GHEASGTVEKVGSSVK 84 PNEV+++ + SD++ + + F +P G+E V KVGS+V Sbjct: 54 PNEVIVKTLGSPVNPSDINQIQGVYPSKPAKTTGFGTTEPAAPCGNEGLFEVIKVGSNVS 113 Query: 85 HLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLP 144 L+ GD V N DD + + P Sbjct: 114 SLEAGDWVIPS--------------HVNFGTWRTHALGNDDD--FIKLPNPAQSKANGKP 157 Query: 145 DNVTFEEGALIE--PLSVGIHACRRGGVTLGHKVLVC--GAGPIGMVTLLVAKAMGAAQV 200 + +T +GA I PL + +T G + G +G + K + + Sbjct: 158 NGLTINQGATISVNPLVAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSI 217 Query: 201 VVTDLSA---TRLSKAKEIGADLVLQISKESPQEI---ARKVEGQLGCKPEVTIECTGAE 254 V ++ KE+GA V+ + + +E ++ Q G + ++ + C G + Sbjct: 218 SVIRDRPNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQSGGEAKLALNCVGGK 277 Query: 255 ASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY----------CNTW 304 +S +G L G+ + T+P + G + +T Sbjct: 278 SSTGIARKLNNNGLMLTYGGMSFQPVTIPTSLYIFKNFTSAGFWVTELLKNNKELKTSTL 337 Query: 305 PVAISMLASKSV----NVKPLVTHRFPLEK-ALEAFETFKKGLGLKI 346 I+ + +++ L PL + + K G L Sbjct: 338 NQIIAWYEEGKLTDAKSIETLYDGTKPLHELYQDGVANSKDGKQLIT 384 >5GXF-A nrPDB Length = 330 Score = 83.5 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 53/298 (17%), Positives = 96/298 (32%), Gaps = 42/298 (14%) Query: 6 KPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKP 65 K L L + P+ EV + + + D G G + K P Sbjct: 9 KDEESGKTQAAVKQLSLTDLPV-----GEVTVAVEYSTVNYKD--GLCIGPGGGLVRKYP 61 Query: 66 MVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPD 125 V G + +GTVE SS + KPGD+V + + Sbjct: 62 HVPGIDFAGTVEN--SSDERYKPGDKVVLTG----------------------WRVGEAH 97 Query: 126 DGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLS----VGIHACRRGGVTLGH-KVLVCG 180 G + A + LP+ + + + + + A G+T GH VLV G Sbjct: 98 WGGYSQKANVRADWLVPLPEGLDTRQAMAVGTAGFTAMLAVMALEDHGLTPGHGPVLVTG 157 Query: 181 -AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQ 239 AG +G V + +G +V +GA ++ E + + R +E + Sbjct: 158 AAGGVGSVATAILAHLG-YEVAAVTGRPETADYLTSLGATQIV-ARDEINETVKRPLESE 215 Query: 240 LGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGV 297 + ++ G + + G ++ +R V++ G+ Sbjct: 216 IWAGC---VDAVGGAMLARVLGQMKYGASVAAVGLAGGAGLPATVIPFLLRGVNLLGI 270 >1O89-A nrPDB Length = 345 Score = 79.3 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 51/284 (17%), Positives = 90/284 (31%), Gaps = 44/284 (15%) Query: 21 RLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVG 80 L+ +PE +V + +H + D G I PM+ G + +GTV Sbjct: 40 TLDESRLPE---GDVTVDVHWSSLNYKDALAITG--KGKIIRNFPMIPGIDFAGTVRT-- 92 Query: 81 SSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFC 140 S G V + EN G L + + Sbjct: 93 SEDPRFHAGQEVLLTGWGVGEN----------------------HWGGLAEQARVKGDWL 130 Query: 141 YKLPDNVTFEEGALIEPLS----VGIHACRRGGVTL--GHKVLVCGAGPIGMVTLLVAKA 194 +P + + +I + + A GV G V+ +G +G + + Sbjct: 131 VAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVGSTAVALLHK 190 Query: 195 MGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAE 254 +G QVV + K +GA VL ++ E + I+ G + Sbjct: 191 LG-YQVVAVSGRESTHEYLKSLGASRVL--PRDEFAESRPLEKQVWAG----AIDTVG-D 242 Query: 255 ASIQAGIYATRSGGNLVLVGLGSEMT-TVPLLHAAIREVDIKGV 297 + + GG + GL T ++ +R V ++GV Sbjct: 243 KVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGV 286 >1V3V-A nrPDB Length = 333 Score = 74.3 bits (181), Expect = 8e-14, Method: Composition-based stats. Identities = 62/347 (17%), Positives = 104/347 (29%), Gaps = 62/347 (17%) Query: 17 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVL-GHEASGT 75 D L+ +P EVLL + + Y RI + +K+ V+ G + + Sbjct: 23 QSDFELKTVELPPLKNGEVLLEALFLSVDP-------YMRIASKRLKEGAVMMGQQVARV 75 Query: 76 VEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKH 135 VE S G V + G + DG Sbjct: 76 VE---SKNSAFPAGSIVLAQSG---------------------WTTHFISDGKGLE---- 107 Query: 136 NAAFCYKLPDNVTF--EEGALIEPLSVGIHAC-RRGGVTLGHKVLV-CGAGPIGMVTLLV 191 + PD + G + P GV G VLV AG +G V + Sbjct: 108 --KLLTEWPDKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGETVLVSAAAGAVGSVVGQI 165 Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECT 251 AK G +VV S +++ K+IG D + E ++ + + Sbjct: 166 AKLKG-CKVVGAAGSDEKIAYLKQIGFDAAFNYKTVNSLE--EALKKASPDGYDCYFDNV 222 Query: 252 GAEASIQAGIYATRSGGNLVLVG---LGSEMTTVPLL----HAAIREVDIKGVFRYCNT- 303 G E + + + G + + G + + M +P +++ I+G Y Sbjct: 223 GGE-FLNTVLSQMKDFGKIAICGAISVYNRMDQLPPGPSPESIIYKQLRIEGFIVYRWQG 281 Query: 304 ------WPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL 344 + + + VT E AF G L Sbjct: 282 DVREKALRDLMKWVLEGKIQYHEHVTKG--FENMPAAFIEMLNGANL 326 >2Y05-A nrPDB Length = 328 Score = 68.9 bits (167), Expect = 4e-12, Method: Composition-based stats. Identities = 52/287 (18%), Positives = 92/287 (32%), Gaps = 32/287 (11%) Query: 83 VKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP-DDGNLCRFYKHNAAFCY 141 K LK GD + + A + + + + + T DG Sbjct: 53 AKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLE------KLLT 106 Query: 142 KLPDNVTFEEG---ALIEPLSVGIHACRRGGVTLGHKVLV-CGAGPIGMVTLLVAKAMGA 197 + PD + + L+ GV G V+V AG +G V +AK G Sbjct: 107 EWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKG- 165 Query: 198 AQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASI 257 +VV S +++ +++G D+V + + ++ + + G E Sbjct: 166 CKVVGAVGSDEKVAYLQKLGFDVVFNYKT--VESLEETLKKASPDGYDCYFDNVGGE-FS 222 Query: 258 QAGIYATRSGGNLVLVGLGSE-MTTVPLLHAAIREVDI--------KGVFRYCNTWPV-- 306 I + G + + G S T PL E+ I V+R+ Sbjct: 223 NTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKA 282 Query: 307 ---AISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL-KIMLK 349 + + + K + E AF KG L K ++K Sbjct: 283 LKDLLKWVLEGKIQYKEYIIEG--FENMPAAFMGMLKGDNLGKTIVK 327 >2VNA-A nrPDB Length = 357 Score = 65.4 bits (158), Expect = 4e-11, Method: Composition-based stats. Identities = 61/352 (17%), Positives = 113/352 (32%), Gaps = 59/352 (16%) Query: 18 GDLRLENYPIPE-PGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPM--VLGHEASG 74 + R+E +P+ +V +R + + ++I + V+ G Sbjct: 22 ENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVDGGGIG 81 Query: 75 TVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP-DDGNLCRFY 133 +E+ S +L GD V P + + L + P DG+L F Sbjct: 82 IIEE--SKHTNLTKGDFVT-SFYWPWQT-------KVILDGNSLEKVDPQLVDGHLSYFL 131 Query: 134 KHNAAFCYKLPDNVTFEEGALIEPLSVGIHAC-RRGGVTLGH--KVLVCGA-GPIGMVTL 189 GA+ P + +G +T G ++V GA G G V Sbjct: 132 ------------------GAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAG 173 Query: 190 LVAKAMGAAQVVVT-DLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248 + +G ++VV + E+G D + K++ E R+ +V Sbjct: 174 QIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRE---SCPAGVDVYF 230 Query: 249 ECTGAEASIQAGIYATRSGGNLVLVG--------LGSEMTTVPLLHAAIREVDI----KG 296 + G S I +++L G + P + A +E +I Sbjct: 231 DNVGGNIS-DTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFL 289 Query: 297 VFRYCNTWP----VAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL 344 V Y + + + +K V + LE AF++ G + Sbjct: 290 VLNYKDKFEPGILQLSQWFKEGKLKIKETVING--LENMGAAFQSMMTGGNI 339 >2ZB3-A nrPDB Length = 353 Score = 61.9 bits (149), Expect = 4e-10, Method: Composition-based stats. Identities = 57/347 (16%), Positives = 108/347 (31%), Gaps = 55/347 (15%) Query: 18 GDLRLENYPIP-EPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEA--SG 74 + R+E + +P +V +R + + +++ + + G Sbjct: 23 ENFRVEEFSLPDALNEGQVQVRTLYLSVDPYMRCKMNEDTGTDYLAPWQLAQVADGGGIG 82 Query: 75 TVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYK 134 VE+ S + L GD V + G + P + DG+L F Sbjct: 83 VVEE--SKHQKLTKGDFVTSFYWPWQTKAILDGNGLEKVDPQLV-------DGHLSYFLG 133 Query: 135 HNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGH--KVLVCGA-GPIGMVTLLV 191 + L+ I +G ++ G ++V GA G G + + Sbjct: 134 -----------------AIGMPGLTSLIGVQEKGHISAGSNQTMVVSGAAGACGSLAGQI 176 Query: 192 AKAMGAAQVVVT-DLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIEC 250 +G ++VV L E+G D + + E R+ +V + Sbjct: 177 GHLLGCSRVVGICGTQEKCLFLTSELGFDAAVNYKTGNVAEQLRE---ACPGGVDVYFDN 233 Query: 251 TGAEASIQAGIYATRSGGNLVLVG--------LGSEMTTVPLLHAAIREVDI----KGVF 298 G + S A I +++L G + P + A +E +I V Sbjct: 234 VGGDIS-NAVISQMNENSHIILCGQISQYSNDVPYPPPLPPAVEAIRKERNITRERFTVL 292 Query: 299 RYCNTWP----VAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 Y + + + VK + LE AF++ G Sbjct: 293 NYKDKFEPGILQLSQWFKEGKLKVKETMAKG--LENMGVAFQSMMTG 337 >2J3K-A nrPDB Length = 345 Score = 58.1 bits (139), Expect = 6e-09, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 44/110 (40%), Gaps = 6/110 (5%) Query: 171 TLGHKVLVCGA-GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAK-EIGADLVLQISKES 228 G V V A G +G + +AK MG VV + S ++ K + G D +ES Sbjct: 154 KEGETVYVSAASGAVGQLVGQLAKMMGCY-VVGSAGSKEKVDLLKTKFGFDDAFNYKEES 212 Query: 229 PQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSE 278 ++ ++ ++ E G + A + G + + G+ S+ Sbjct: 213 --DLTAALKRCFPNGIDIYFENVGG-KMLDAVLVNMNMHGRIAVCGMISQ 259 >1XLT-A nrPDB Length = 384 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 1/50 (2%) Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIG 217 G +VLV G G G+ + AK +GA V+ TD+ A + + +G Sbjct: 167 AGTVPPARVLVFGVGVAGLQAIATAKRLGA-VVMATDVRAATKEQVESLG 215 >4DIO-A nrPDB Length = 405 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 30/174 (17%), Positives = 58/174 (33%), Gaps = 26/174 (14%) Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKE 227 G K+ V GAG G+ + A+ +GA V TD+ + +GA + +E Sbjct: 185 AGTVPAAKIFVMGAGVAGLQAIATARRLGA-VVSATDVRPAAKEQVASLGAKFIAVEDEE 243 Query: 228 ----------------SPQEIARKVEGQLGCKPEVTIECT---GAEA---SIQAGIYATR 265 Q + + K ++ I G A + + + + Sbjct: 244 FKAAETAGGYAKEMSGEYQVKQAALVAEHIAKQDIVITTALIPGRPAPRLVTREMLDSMK 303 Query: 266 SGGNLVLVGL--GSEMTTVPLLHAA-IREVDIKGVFRYCNTWPVAISMLASKSV 316 G +V + + G + + V I G + S+L +K++ Sbjct: 304 PGSVVVDLAVERGGNIEGAEAGKVTEVGGVRIVGHLNVAGRIAASASLLYAKNL 357 >5EKU-A nrPDB Length = 390 Score = 38.4 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 162 IHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE 215 + + VT VL GAG G+++L+ AK +GA VV + S A+E Sbjct: 85 YYEVLKKHVTPETGVLEIGAGS-GLLSLMAAK-LGAKWVVAVEGSEELAKLARE 136 >4M36-A nrPDB Length = 343 Score = 38.4 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 162 IHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE 215 + + VT VL GAG G+++L+ AK +GA VV + S A+E Sbjct: 50 YYEVLKKHVTPETGVLEIGAGS-GLLSLMAAK-LGAKWVVAVEGSEELAKLARE 101 >2EGU-A nrPDB Length = 308 Score = 38.4 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 33/79 (41%), Gaps = 2/79 (2%) Query: 164 ACRRGGVTLGHKVL--VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 221 A + G + G ++ G IG+ + AK A V+ +S R + + GA+LV Sbjct: 56 AEKAGKLKPGDTIVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAELV 115 Query: 222 LQISKESPQEIARKVEGQL 240 L + + K E + Sbjct: 116 LTPGAQGMRGAIAKAEELV 134 >3MGG-A nrPDB Length = 276 Score = 38.4 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 23/113 (20%), Positives = 41/113 (36%), Gaps = 19/113 (16%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQE 231 G KVL G G IG T+++AK A++ D+S L KA+E K + Sbjct: 37 PGAKVLEAGCG-IGAQTVILAKNNPDAEITSIDISPESLEKARE-------NTEKNGIKN 88 Query: 232 IARKVEGQL-----GCKPEVTIEC------TGAEASIQAGIYATRSGGNLVLV 273 + + C E ++++ + GG + ++ Sbjct: 89 VKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVI 141 >4AEC-A nrPDB Length = 430 Score = 38.1 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 35/86 (40%), Gaps = 3/86 (3%) Query: 164 ACRRGGVTLGHKVLV---CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADL 220 A ++G ++ G VLV G IG+ + ++ + +S R K GA+L Sbjct: 165 AEQKGFISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAEL 224 Query: 221 VLQISKESPQEIARKVEGQLGCKPEV 246 VL + +K E L P+ Sbjct: 225 VLTDPAKGMTGAVQKAEEILKNTPDA 250 >1X14-A nrPDB Length = 401 Score = 37.7 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 24/52 (46%), Gaps = 1/52 (1%) Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGAD 219 G KV+V GAG G+ + A ++GA V D + + +GA+ Sbjct: 167 AGKVPPAKVMVIGAGVAGLAAIGAANSLGA-IVRAFDTRPEVKEQVQSMGAE 217 >1ZCJ-A nrPDB Length = 463 Score = 37.3 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 20/52 (38%), Gaps = 3/52 (5%) Query: 166 RRGGVTLGHKVLVCGAGPIG-MVTLLVAKAMGAAQVVVTDLSATRLSKAKEI 216 + V V G G +G + + A+ VV + +L AK+I Sbjct: 30 KTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 79 >1W1U-A nrPDB Length = 557 Score = 36.5 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 35/184 (19%), Positives = 57/184 (30%), Gaps = 11/184 (5%) Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKE 227 GG G VL G G +G L A GA + + +R+ E + Sbjct: 162 GGSLKGKWVLTAGLGGMGGAQPLAATLAGACS-LNIESQQSRIDFRLE---TRYVDEQAT 217 Query: 228 SPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHA 287 + ++ ++I G A I + G +V PL Sbjct: 218 DLDDALVRIAKYTAEGKAISIALHGNAAEI--LPELVKRGVRPDMV-TDQTSAHDPLNGY 274 Query: 288 AIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIM 347 + T P A+ A +S+ V V +K + TF G ++ M Sbjct: 275 LPAGWTWEQYRDRAQTEPAAVVKAAKQSMAVH--VQAMLDFQK--QGVPTFDYGNNIRQM 330 Query: 348 LKCD 351 K + Sbjct: 331 AKEE 334 >4N7R-A nrPDB Length = 472 Score = 36.5 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 32/94 (34%), Gaps = 6/94 (6%) Query: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHK------VLVCGA 181 R + V E +SV A + L + V GA Sbjct: 156 GFGRNISGLFKHAITVGKRVRTETNIASGAVSVSSAAVELALMKLPQSSNVSARMCVIGA 215 Query: 182 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE 215 G +G + + A G +VVV + S R+S +E Sbjct: 216 GKMGKLVIKHLMAKGCTKVVVVNRSEERVSAIRE 249 >1I9G-A nrPDB Length = 280 Score = 36.5 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 42/112 (37%), Gaps = 6/112 (5%) Query: 165 CRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMG-AAQVVVTDLSATRLSKAKEIGADLVLQ 223 G + G +VL GAG G +TL + +A+G A QV+ + A A+ Sbjct: 92 VHEGDIFPGARVLEAGAGS-GALTLSLLRAVGPAGQVISYEQRADHAEHARRN-VSGCYG 149 Query: 224 ISKESPQEIARKVEGQL---GCKPEVTIECTGAEASIQAGIYATRSGGNLVL 272 ++ + + + G ++ + A +GG L++ Sbjct: 150 QPPDNWRLVVSDLADSELPDGSVDRAVLDMLAPWEVLDAVSRLLVAGGVLMV 201 >4OM8-A nrPDB Length = 309 Score = 36.5 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 38/216 (17%), Positives = 77/216 (35%), Gaps = 61/216 (28%) Query: 175 KVLVCGAGPIG-MVTLLVAKAMGAAQVVVTDLSATRLSKAKEI----------------- 216 + + G G +G + +A+ G QVV D++ + +A+ + Sbjct: 4 NIAIIGLGTMGPGMAARLAR--GGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPS 61 Query: 217 -----------------GADLVLQISKESP---QEIARKVEGQLGCKPEVTIECTGAEAS 256 GADLV++ E+ ++ R ++G +G V + +G + Sbjct: 62 AGVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPIT 121 Query: 257 -IQAGIYATRSGGNLVLVGL--GSEMTTVPLLHAAIREV-------DIKGVFRYCNTWPV 306 +QA I +VG+ + +P++ E I+ + R PV Sbjct: 122 KLQAHISYPER-----MVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIGLLPV 176 Query: 307 AISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 342 + +V V +R EA + ++G+ Sbjct: 177 VVKK------DVPGFVENRVLYALLREAVDLVERGV 206 >3ZWA-A nrPDB Length = 742 Score = 36.5 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 20/52 (38%), Gaps = 3/52 (5%) Query: 166 RRGGVTLGHKVLVCGAGPIG-MVTLLVAKAMGAAQVVVTDLSATRLSKAKEI 216 + V V G G +G + + A+ VV + +L AK+I Sbjct: 309 KTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 358 >2RIR-A nrPDB Length = 300 Score = 36.1 bits (82), Expect = 0.024, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 41/100 (41%), Gaps = 7/100 (7%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 G +V V G G GM A+GA V SA L++ E+G ++ + +E Sbjct: 157 GSQVAVLGLGRTGMTIARTFAALGANVKVGARSSAH-LARITEMG---LVPFHTDELKEH 212 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQAGIY---ATRSGGN 269 + ++ + P + + T + + A+R GG Sbjct: 213 VKDIDICINTIPSMILNQTVLSSMTPKTLILDLASRPGGT 252 >1CYD-A nrPDB Length = 244 Score = 35.8 bits (81), Expect = 0.027, Method: Composition-based stats. Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Query: 173 GHKVLVCGAG-PIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE 215 G + LV GAG IG T+ A GA V VT ++ +S AKE Sbjct: 7 GLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKE 50 >5ILO-A nrPDB Length = 271 Score = 35.8 bits (81), Expect = 0.028, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 31/88 (35%), Gaps = 8/88 (9%) Query: 173 GHKVLVCG-AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV-------LQI 224 G +V G AG IG+ A GAA+V + DL K A + + Sbjct: 15 GKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDV 74 Query: 225 SKESPQEIARKVEGQLGCKPEVTIECTG 252 + + E + + ++ + G Sbjct: 75 ANKKGVEATYEEIAKTFGNIDIVVNVAG 102 >3VPX-A nrPDB Length = 364 Score = 35.8 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 22/51 (43%), Gaps = 2/51 (3%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKA-KEIGADLV 221 G V V G G + GA ++++TD++ + +A GA V Sbjct: 172 AGKTVAVQGVGNVAYALCEYLHEEGA-KLIITDINEEAVQRAVDAFGATAV 221 >2ISQ-A nrPDB Length = 320 Score = 35.8 bits (81), Expect = 0.033, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 30/85 (35%), Gaps = 3/85 (3%) Query: 164 ACRRGGVTLGHKVLV---CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADL 220 A ++G + G VL+ G +G+ AK + +S R G +L Sbjct: 55 AEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVEL 114 Query: 221 VLQISKESPQEIARKVEGQLGCKPE 245 VL + + K E L P Sbjct: 115 VLTDPAKGMKGAIAKAEEILAKTPN 139 >1E3W-A nrPDB Length = 261 Score = 35.8 bits (81), Expect = 0.033, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL---QISKESPQEI 232 V+ GA +G+ T GA V++ ++ ++AK++G + + ++ E + Sbjct: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQAG 260 A + + + +V + C G +I+ Sbjct: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKTY 101 >5Z1Z-A nrPDB Length = 329 Score = 35.4 bits (80), Expect = 0.036, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 221 G V G G IG+ L + K G +++ D + + A E+G + V Sbjct: 144 GKTAGVIGTGKIGVAMLRILKGFGM-RLLAFDPYPS--AAALELGVEYV 189 >2ZJ1-A nrPDB Length = 495 Score = 35.4 bits (80), Expect = 0.036, Method: Composition-based stats. Identities = 25/103 (24%), Positives = 39/103 (37%), Gaps = 16/103 (15%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 G KVL+CG G +G K GA +V VT++ +A G D+V Sbjct: 275 GKKVLICGYGDVGKGCAEAMKGQGA-RVSVTEIDPINALQAMMEGFDVV----------- 322 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQ-AGIYATRSGGNLVLVG 274 + ++ + TG + I I A + L +G Sbjct: 323 ---TVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIG 362 >1ZFN-A nrPDB Length = 253 Score = 35.4 bits (80), Expect = 0.038, Method: Composition-based stats. Identities = 22/133 (16%), Positives = 44/133 (33%), Gaps = 24/133 (18%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE--IGADLVLQISKESPQE 231 +VL+ G G +G L G +V+ D LS + + + K + Sbjct: 31 SQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQ 90 Query: 232 --------------IARKVEG----QLGCKPEVTIECTGAEASIQ----AGIYATRSGGN 269 + +++ G + +V ++CT A+ Q A + Sbjct: 91 QRLTQLNPDIQLTALQQRLTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLIT 150 Query: 270 LVLVGLGSEMTTV 282 VG G ++ + Sbjct: 151 ASAVGFGGQLMVL 163 >3D3W-A nrPDB Length = 244 Score = 35.4 bits (80), Expect = 0.043, Method: Composition-based stats. Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Query: 172 LGHKVLVCGAG-PIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE 215 G +VLV GAG IG T+ A GA V V+ A S +E Sbjct: 6 AGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRE 50 >4CUK-A nrPDB Length = 338 Score = 35.0 bits (79), Expect = 0.046, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 22/49 (44%), Gaps = 3/49 (6%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 221 G V G G IG+ L + K G +++ D + A ++G + V Sbjct: 144 GKTAGVIGTGKIGVAALRILKGFGM-RLLAFDPYPST--AALDLGVEYV 189 >3GRP-A nrPDB Length = 266 Score = 35.0 bits (79), Expect = 0.051, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 30/85 (35%), Gaps = 4/85 (4%) Query: 172 LGHKVLVCGA-GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL---QISKE 227 G K LV GA G IG A GA + A ++G D+ + +S Sbjct: 26 TGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLSDR 85 Query: 228 SPQEIARKVEGQLGCKPEVTIECTG 252 + +V + ++ + G Sbjct: 86 KSIKQLAEVAEREMEGIDILVNNAG 110 >1BW9-B nrPDB Length = 356 Score = 35.0 bits (79), Expect = 0.051, Method: Composition-based stats. Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 161 GIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADL 220 A R G G VLV G G +G +A GA Q++V D R++ A +G Sbjct: 164 ATVAHRGLGSLDGLTVLVQGLGAVGGSLASLAAEAGA-QLLVADTDTERVAHAVALGHTA 222 Query: 221 V 221 V Sbjct: 223 V 223 >3EMK-A nrPDB Length = 246 Score = 35.0 bits (79), Expect = 0.053, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 28/85 (32%), Gaps = 4/85 (4%) Query: 172 LGHKVLVCGA-GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL---QISKE 227 G K LV GA G +G A GA + A E+G + + +S Sbjct: 6 TGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLSDR 65 Query: 228 SPQEIARKVEGQLGCKPEVTIECTG 252 + + + ++ + G Sbjct: 66 EAVKALGQKAEEEMGGVDILVNNAG 90 >6BII-A nrPDB Length = 333 Score = 35.0 bits (79), Expect = 0.054, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 20/47 (42%), Gaps = 2/47 (4%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGAD 219 G + + G G IG AK G ++ + + KE+GA+ Sbjct: 150 GKTIGIVGFGRIGQAIAKRAKGFGMR--ILYTARSRKPEAEKELGAE 194 >5D84-A nrPDB Length = 326 Score = 35.0 bits (79), Expect = 0.055, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Query: 163 HACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTD--LSATRLSKAKEIGADL 220 H + G +T ++ +G +G+ ++AK G V D +S T L K GA++ Sbjct: 57 HGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGANV 116 >5F8E-A nrPDB Length = 377 Score = 35.0 bits (79), Expect = 0.056, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 41/109 (37%), Gaps = 8/109 (7%) Query: 170 VTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSK----AKEIG-ADLVLQI 224 + G V G G G L+A+A GA++ D S ++ A +G A+ + Sbjct: 185 LRSGADVADFGCGS-GRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFER 243 Query: 225 SKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLV 273 E+ + + + + +Q A R GG L++V Sbjct: 244 H--DLAELDKVGAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMV 290 >2O23-A nrPDB Length = 265 Score = 35.0 bits (79), Expect = 0.058, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL---QISKESPQEI 232 V+ GA +G+ T GA+ V++ ++ ++AK++G + V ++ E + Sbjct: 16 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 75 Query: 233 ARKVEGQLGCKPEVTIECTGAEAS 256 A + + +V + C G + Sbjct: 76 ALALAKGKFGRVDVAVNCAGIAVA 99 >1V9L-A nrPDB Length = 421 Score = 34.6 bits (78), Expect = 0.060, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 18/34 (52%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLS 206 G V + G G +G T + MGA + V+D++ Sbjct: 210 GKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDIN 243 >5JXW-A nrPDB Length = 498 Score = 34.6 bits (78), Expect = 0.064, Method: Composition-based stats. Identities = 33/174 (18%), Positives = 60/174 (34%), Gaps = 39/174 (22%) Query: 169 GVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKES 228 + G K++V G G +G +GA +V+VT++ LQ S E Sbjct: 267 QMLAGKKIVVLGYGEVGKGCAQGLSGVGA-RVIVTEIDPIC-----------ALQASMEG 314 Query: 229 PQEIARKVEGQLGCKPEVTIECTGAEASIQ-AGIYATRSGGNLVLVGLGSEMTTVPLLHA 287 Q + + + ++ I TG + I + + + +G + Sbjct: 315 YQVSVLE---DVVSEADIFITATGNKDVITVEHMRKMKENAYIANIGHFDD--------- 362 Query: 288 AIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 341 E+D+ G+ Y K + VK V H+F ++ KG Sbjct: 363 ---EIDVYGLENYPG----------IKVIEVKQNV-HKFTFPDTQKSVILLCKG 402 >1DOD-A nrPDB Length = 394 Score = 34.6 bits (78), Expect = 0.064, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 43/118 (36%), Gaps = 14/118 (11%) Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATR-----LSKAKEIGADLVLQISKESPQ 230 V + GAGP G++ + G V++ + + E G ++ + +E+ Sbjct: 5 VAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQG---MVDLLREAGV 61 Query: 231 EIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAA 288 + +G + E+ G I + SGG V V G T L+ A Sbjct: 62 DRRMARDGLVHEGVEIAF--AGQRRRID--LKRL-SGGKTVTV-YGQTEVTRDLMEAR 113 >4XIJ-A nrPDB Length = 275 Score = 34.6 bits (78), Expect = 0.066, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 21/63 (33%), Gaps = 4/63 (6%) Query: 160 VGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATR----LSKAKE 215 + T G LV G+G ++ +G ++ + + + A+ Sbjct: 113 TDVDGVTGALGTAGDSALVIGSGGTAPAAVVALAELGVQRITIVARDEGKASRLVDLARR 172 Query: 216 IGA 218 GA Sbjct: 173 CGA 175 >1GPJ-A nrPDB Length = 404 Score = 34.6 bits (78), Expect = 0.070, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 5/69 (7%) Query: 158 LSVGIHACRRGGVTLGH----KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATR-LSK 212 +S+G A LG VLV GAG +G G V+V + + R + Sbjct: 148 VSIGSAAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVEL 207 Query: 213 AKEIGADLV 221 A+++G + V Sbjct: 208 ARDLGGEAV 216 >5UYY-A nrPDB Length = 381 Score = 34.6 bits (78), Expect = 0.074, Method: Composition-based stats. Identities = 28/184 (15%), Positives = 55/184 (29%), Gaps = 23/184 (12%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIA 233 KV++ G G IG L K + D+ ++ +AKE+ V+ Q Sbjct: 18 KKVVLIGTGLIGGSLALAIKKDHDVTITGYDIFQEQVERAKEL---HVVDEIAVDLQHAC 74 Query: 234 RKVEGQLGCKPEVTIECTGAEASIQAGIYA----TRSGGNLVLVGLGSEMTTVPLLHAAI 289 + + + + E + + R + VG Sbjct: 75 EE--------AHLIVFASPVEETKKLLHKLASFHLREDVIVTDVGSTKGSIMNEAEALFS 126 Query: 290 REVDIKGVFRYCNTWPVAISMLASKSVN-----VKPLVTHRFPLEKALEAFETFKKGLGL 344 +E+ G + + + + P+ H P E E + + KG G Sbjct: 127 KEISFIGGHPMAGSHKTGVESAKAHLFENAFYILTPM--HHVPNEHVEE-LKDWLKGTGS 183 Query: 345 KIML 348 ++ Sbjct: 184 HFLV 187 >4E4T-A nrPDB Length = 419 Score = 34.6 bits (78), Expect = 0.076, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 38/120 (31%), Gaps = 11/120 (9%) Query: 157 PLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEI 216 P S+ + G + + G G +G + A++MG +V V D A Sbjct: 19 PGSMTATPDSVSPILPGAWLGMVGGGQLGRMFCFAAQSMG-YRVAVLDPDP-----ASPA 72 Query: 217 GADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEAS---IQAGIYATRSGGNLVLV 273 GA V + + + G V+ E A+ A G V V Sbjct: 73 GA--VADRHLRAAYDDEAALAELAGLCEAVSTEFENVPAASLDFLARTTFVAPAGRCVAV 130 >3C3P-A nrPDB Length = 210 Score = 34.2 bits (77), Expect = 0.088, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 31/91 (34%), Gaps = 2/91 (2%) Query: 127 GNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGM 186 G A + + E I G + V+V G G +G Sbjct: 11 GAYLDGLLPEADPVVAAMEQIARERNIPIVDRQTGRLLYLLARIKQPQLVVVPGDG-LGC 69 Query: 187 VTLLVAKAMG-AAQVVVTDLSATRLSKAKEI 216 + A+A+ +++VV+ D + A+ + Sbjct: 70 ASWWFARAISISSRVVMIDPDRDNVEHARRM 100 >2B25-A nrPDB Length = 336 Score = 34.2 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Query: 169 GVTLGHKVLVCGAGPIGMVTLLVAKAMGA-AQVVVTDLSATRLSKAKE 215 + G VL G+G G ++L ++KA+G+ +V+ ++ AK+ Sbjct: 102 DINPGDTVLEAGSGSGG-MSLFLSKAVGSQGRVISFEVRKDHHDLAKK 148 >6C55-A nrPDB Length = 340 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 22/65 (33%), Gaps = 1/65 (1%) Query: 157 PLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEI 216 +V + G K+ V G G G K G V+ + KAKE Sbjct: 1 MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRS-FDKAKED 59 Query: 217 GADLV 221 G D+ Sbjct: 60 GFDVF 64 >2HMT-A nrPDB Length = 144 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 29/82 (35%), Gaps = 8/82 (9%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL-QISKESPQEI 232 + V G G G + MG +V+ D++ +++ V+ ++E+ Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEEN---- 61 Query: 233 ARKVEGQLGCKPEVTIECTGAE 254 ++ E I GA Sbjct: 62 --ELLSLGIRNFEYVIVAIGAN 81 >2VHY-A nrPDB Length = 377 Score = 33.8 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 42/106 (39%), Gaps = 7/106 (6%) Query: 169 GVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV--LQISK 226 GV V+V GAG G +A MGA V V D++ +L +++ A+ + Sbjct: 165 GVEPAD-VVVIGAGTAGYNAARIANGMGA-TVTVLDINIDKL---RQLDAEFCGRIHTRY 219 Query: 227 ESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVL 272 S E+ V+ V + A + + A G +++ Sbjct: 220 SSAYELEGAVKRADLVIGAVLVPGAKAPKLVSNSLVAHMKPGAVLV 265 >4K2X-A nrPDB Length = 523 Score = 33.4 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 23/44 (52%), Gaps = 1/44 (2%) Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGAD 219 V++ GAGP G++ + GA + +V + A + +K +G Sbjct: 25 VVIAGAGPTGLMLACELRLAGA-RTLVLERLAEPVDFSKALGVH 67 >6BQ5-A nrPDB Length = 331 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 13/92 (14%), Positives = 25/92 (27%), Gaps = 5/92 (5%) Query: 160 VGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGA- 218 +H V + G G G + + +VV+ D+ + K Sbjct: 90 CLVHPALLHHPMP-KNVFIMG-GGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVV 147 Query: 219 --DLVLQISKESPQEIARKVEGQLGCKPEVTI 248 + E A+ K +V + Sbjct: 148 NKEAFHDSRLEVVINDAKAELEGKEEKYDVIV 179 >5BUT-A nrPDB Length = 288 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 29/82 (35%), Gaps = 8/82 (9%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL-QISKESPQEI 232 + V G G G + MG +V+ D++ +++ V+ ++E+ Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEEN---- 61 Query: 233 ARKVEGQLGCKPEVTIECTGAE 254 ++ E I GA Sbjct: 62 --ELLSLGIRNFEYVIVAIGAN 81 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 29/82 (35%), Gaps = 8/82 (9%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL-QISKESPQEI 232 + V G G G + MG +V+ D++ +++ V+ ++E+ Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEEN---- 203 Query: 233 ARKVEGQLGCKPEVTIECTGAE 254 ++ E I GA Sbjct: 204 --ELLSLGIRNFEYVIVAIGAN 223 >4J90-A nrPDB Length = 222 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 28/82 (34%), Gaps = 8/82 (9%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL-QISKESPQEI 232 + V G G G MG +V+ D++ +++ V+ ++E+ Sbjct: 7 KQFAVIGLGRFGGSICKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEEN---- 61 Query: 233 ARKVEGQLGCKPEVTIECTGAE 254 ++ E I GA Sbjct: 62 --ELLSLGIRNFEYVIVAIGAN 81 >2YVG-A nrPDB Length = 408 Score = 33.4 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 45/129 (34%), Gaps = 17/129 (13%) Query: 144 PDNVTFEEGA--LIEPLSVGIHACR-RGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQV 200 P + +GA + L A R + G+ ++L+ G G IG+ A+ G V Sbjct: 113 PRALPTLQGATMPVHTLRTLEDARRIQAGLRPQSRLLIVGGGVIGLELAATARTAGVH-V 171 Query: 201 VVTDLSATRLSKA-------------KEIGADLVLQISKESPQEIARKVEGQLGCKPEVT 247 + + +S+A G DL + S + ++ ++ Sbjct: 172 SLVETQPRLMSRAAPATLADFVARYHAAQGVDLRFERSVTGSVDGVVLLDDGTRIAADMV 231 Query: 248 IECTGAEAS 256 + G A+ Sbjct: 232 VVGIGVLAN 240 >6DLL-A nrPDB Length = 398 Score = 33.4 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 44/118 (37%), Gaps = 14/118 (11%) Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATR-----LSKAKEIGADLVLQISKESPQ 230 V + GAGP G++ + G ++V +A + E G + + +E+ Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIVERQTAEYVLGRIRAGVLEQG---TVDLLREAGV 64 Query: 231 EIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAA 288 EG + E+ + G + + A GG V+V G T L+ A Sbjct: 65 AERMDREGLVHEGVELLV--GGRRQRLD--LKALT-GGKTVMV-YGQTEVTRDLMQAR 116 >1DXY-A nrPDB Length = 333 Score = 33.4 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 23/136 (16%), Positives = 40/136 (29%), Gaps = 18/136 (13%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATR-----------LSKAKEIGADLVL 222 V V G G IG V + + K GA +V+ D + K+ V+ Sbjct: 146 QTVGVMGTGHIGQVAIKLFKGFGA-KVIAYDPYPMKGDHPDFDYVSLEDLFKQ---SDVI 201 Query: 223 QISKESPQE---IARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEM 279 + ++ I + L + I + + G L VG+ + Sbjct: 202 DLHVPGIEQNTHIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAGVGIDTYE 261 Query: 280 TTVPLLHAAIREVDIK 295 L + K Sbjct: 262 YETEDLLNLAKHGSFK 277 >1ZFJ-A nrPDB Length = 491 Score = 33.1 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 2/87 (2%) Query: 193 KAMGAAQVVVTDLSATRLSKAKEIGAD-LVLQISKESPQEIARKVEGQLGCKPEVTIECT 251 + + AA V VT + R E GAD +V+ + + RK+ P T+ Sbjct: 221 RLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNRTL-IA 279 Query: 252 GAEASIQAGIYATRSGGNLVLVGLGSE 278 G A+ + +G ++V VG+G Sbjct: 280 GNIATAEGARALYDAGVDVVKVGIGPG 306 >4A6N-B nrPDB Length = 398 Score = 33.1 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 6/92 (6%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIA 233 V + G GP+G+ + + G V V + R A+ G L + K S QE Sbjct: 27 KNVAIIGGGPVGLTMAKLLQQNG-IDVSVYERDNDRE--ARIFGGT--LDLHKGSGQEAM 81 Query: 234 RKVEGQLGCKPEVTIECTGAEASIQAGIYATR 265 +K G L ++ + A + I +T+ Sbjct: 82 KK-AGLLQTYYDLALPMGVNIADEKGNILSTK 112 >3FBT-A nrPDB Length = 282 Score = 33.1 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 15/118 (12%), Positives = 33/118 (27%), Gaps = 23/118 (19%) Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATR------------LSKAKEIGADLVLQ 223 +V G+G L K A + V + + + + D+++ Sbjct: 125 CVVLGSGGAARAVLQYLKDNFAKDIYVVTRNPEKTSEIYGEFKVISYDELSNLKGDVIIN 184 Query: 224 ------ISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGL 275 KE + ++V + ++ + R G + GL Sbjct: 185 CTPKGMYPKEGESPVDKEVVAKFSSAVDLIYNPVET-----LFLKYARESGVKAVNGL 237 >5FUB-A nrPDB Length = 337 Score = 33.1 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 25/54 (46%) Query: 179 CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 CG G I + L+AK G V + ++ K+ G D V+ + +E + + Sbjct: 53 CGTGVISLFCALLAKPAGVYAVEASSMAEHTEELVKQNGCDGVVTVFQERAENL 106 >1XDW-A nrPDB Length = 331 Score = 33.1 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 12/26 (46%) Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQV 200 V V G G IG V + MGA + Sbjct: 148 TVGVVGLGRIGRVAAQIFHGMGATVI 173 >2A9F-A nrPDB Length = 398 Score = 33.1 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 28/164 (17%), Positives = 58/164 (35%), Gaps = 11/164 (6%) Query: 142 KLPDNVTFEEGALIEPLSVGIHACRRGGVTLGH-KVLVCGAGPIGMVTLLVAKAMGAAQV 200 +P + G I L+ ++ + +L ++V G G G+ A GA +V Sbjct: 156 HIPVFHDDQHGTAIVVLAAIFNSLKLLKKSLDEVSIVVNGGGSAGLSITRKLLAAGATKV 215 Query: 201 VVTD----LSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEAS 256 V D ++ ++ A L I+K + +E ++ I A Sbjct: 216 TVVDKFGIINEQEAAQL----APHHLDIAKVTNREFKSGTLEDALEGADIFI-GVSAPGV 270 Query: 257 IQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY 300 ++A + ++ V+ + + + + A I G R Sbjct: 271 LKAE-WISKMAARPVIFAMANPIPEIYPDEALEAGAYIVGTGRS 313 >5VMT-A nrPDB Length = 342 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 41/121 (33%), Gaps = 17/121 (14%) Query: 175 KVLVCGAGPIGMVTL-LVAKAMGAAQVVVTDLSAT--------------RLSKAKEIGAD 219 KV + G G IG + L + KA G V DL+ R E+ D Sbjct: 12 KVAINGFGRIGRLALRQIEKAHGIEVAAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDD 71 Query: 220 -LVLQISKESPQEIARKVEGQLGC-KPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGS 277 +V+ + E G +V +ECTG + R+G V++ Sbjct: 72 AIVVNGREIKVFANPNPEELPWGELGVDVVLECTGFFTNKTKAEAHIRAGARKVVISAPG 131 Query: 278 E 278 Sbjct: 132 G 132 >3G1U-A nrPDB Length = 437 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 30/86 (34%), Gaps = 15/86 (17%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQE 231 G VCG G +G +A GA +VVVT++ + + S + Sbjct: 211 AGKTCCVCGYGDVGKGCAAALRAFGA-RVVVTEVDP--------------INALQASMEG 255 Query: 232 IARKVEGQLGCKPEVTIECTGAEASI 257 + + + + TG + I Sbjct: 256 YQVALVEDVMADAHIFVTTTGNDDII 281 >4COO-A nrPDB Length = 563 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 30/75 (40%), Gaps = 5/75 (6%) Query: 164 ACRRGGVTLGHKVL--VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 221 A R G + G ++ G IG+ + V+ +S+ ++ + +GA++V Sbjct: 152 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 211 Query: 222 ---LQISKESPQEIA 233 +SP+ Sbjct: 212 RTPTNARFDSPESHV 226 >5JJC-A nrPDB Length = 342 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 8/63 (12%) Query: 164 ACRRGGVTLGHKVLVCG-AG--PIGMVTLLVAKAMGAAQVVVT--DLSATRLSKAKEIGA 218 A +RG + G V+V G AG IG+ +VAKA+G +V S + + +GA Sbjct: 53 AEKRGLLRPG-GVIVEGTAGNTGIGL--TMVAKALGYRTAIVIPETASQEKKDALRLLGA 109 Query: 219 DLV 221 +L+ Sbjct: 110 ELI 112 >4XGI-A nrPDB Length = 436 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 50/143 (34%), Gaps = 29/143 (20%) Query: 158 LSVGIHACRRGGVTL-GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLS-----ATRLS 211 VG A ++ GV + G ++ V G G +G + + + GA + V D + + Sbjct: 215 FVVGCEAAKKKGVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVIAVQDHTGTIHQPAGVD 274 Query: 212 KAKEI-------------GAD-------LVLQISKESPQEIARKVEGQLGCKPE--VTIE 249 AK + GA+ ++ P + ++ + K + +E Sbjct: 275 TAKLLDHVGRTGGVAGFEGAEPMPNDEFWTVETEILIPAALENQITEKNASKIRTKIIVE 334 Query: 250 CTGAEASIQAGIYATRSGGNLVL 272 + A + G LV+ Sbjct: 335 GANGPTTT-AADDILSANGVLVI 356 >1V8B-A nrPDB Length = 479 Score = 32.7 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 43/112 (38%), Gaps = 16/112 (14%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 G V++CG G +G K +GA +V +T++ +A G ++V Sbjct: 257 GKIVVICGYGDVGKGCASSMKGLGA-RVYITEIDPICAIQAVMEGFNVV----------- 304 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQ-AGIYATRSGGNLVLVGLGSEMTTVP 283 ++ K + I CTG I+ + ++ + +G + V Sbjct: 305 ---TLDEIVDKGDFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHFDDEIQVN 353 >1M54-A nrPDB Length = 363 Score = 32.7 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 30/75 (40%), Gaps = 5/75 (6%) Query: 164 ACRRGGVTLGHKVL--VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 221 A R G + G ++ G IG+ + V+ +S+ ++ + +GA++V Sbjct: 87 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 146 Query: 222 ---LQISKESPQEIA 233 +SP+ Sbjct: 147 RTPTNARFDSPESHV 161 >5MMS-A nrPDB Length = 408 Score = 32.7 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 30/75 (40%), Gaps = 5/75 (6%) Query: 164 ACRRGGVTLGHKVL--VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 221 A R G + G ++ G IG+ + V+ +S+ ++ + +GA++V Sbjct: 130 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 189 Query: 222 ---LQISKESPQEIA 233 +SP+ Sbjct: 190 RTPTNARFDSPESHV 204 >5U9P-A nrPDB Length = 265 Score = 32.7 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 35/90 (38%), Gaps = 9/90 (10%) Query: 173 GHKVLVCGAG-PIGMVTLLVAKAMGAAQVVVTDLSATRLS-KAKE-----IGADLVLQIS 225 G + L+ G+G IG+ GAA +V+ D + + + A+ AD + Sbjct: 20 GRRALITGSGRGIGLTLARGLAEAGAA-IVINDRNEEKAATLARRFRDEGFAADHAVFDV 78 Query: 226 KESPQEIARKVEGQLGCKP-EVTIECTGAE 254 E Q A E + ++ + G + Sbjct: 79 AEHAQVRAAIDEFEARVGAIDILVNNAGIQ 108 >3HM2-A nrPDB Length = 178 Score = 32.3 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 35/107 (32%), Gaps = 11/107 (10%) Query: 182 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSK----AKEIGADLVLQISKESPQEIARKVE 237 G G + + ++ V ++S R + A +G + + + +P+ Sbjct: 34 GGSGSIAIEWLRSTPQTTAVCFEISEERRERILSNAINLGVSDRIAVQQGAPRAF----- 88 Query: 238 GQLGCKPEVTIECTG--AEASIQAGIYATRSGGNLVLVGLGSEMTTV 282 + P+V G A A GG LV + E + Sbjct: 89 DDVPDNPDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAVTVESEQM 135 >6ACF-A nrPDB Length = 367 Score = 32.3 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 8/53 (15%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAM---GAAQVVVTDLSATRLSKA-KEIGADLV 221 G V V G +G V + + + GA +++VTD++ +++A +E GA V Sbjct: 173 GKVVAVQG---VGNVAYHLCRHLHEEGA-KLIVTDINKEAVARAVEEFGAKAV 221 >3X2F-A nrPDB Length = 411 Score = 32.3 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 52/150 (34%), Gaps = 18/150 (12%) Query: 170 VTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESP 229 + G V+V G G G L A +GA +V+VT++ + +A G + Sbjct: 194 LVAGKNVVVAGYGWCGRGIALRAAGLGA-RVIVTEVDPVKAVEAIMDGFTV------MPM 246 Query: 230 QEIARKVEGQLGCKPEVTIECTGAEASI-QAGIYATRSGGNLVLVGLGSEMTTVPLLHAA 288 +E + + I +G + + I + + G L G + V +L Sbjct: 247 KEAVKI--------ADFVITASGNTDVLSKEDILSLKDGAVLANAGHFNVEIPVRVLEEI 298 Query: 289 IREV--DIKGVFRYCNTWPVAISMLASKSV 316 E V Y + +LA + Sbjct: 299 AVEKFEARPNVTGYTLENGKTVFLLAEGRL 328 >3PPI-A nrPDB Length = 281 Score = 32.3 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 35/98 (35%), Gaps = 7/98 (7%) Query: 180 GAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIG--ADLV-LQISKESPQEIARKV 236 GAG +G T+ A G V+ + + A E+G A+ V ++ E A + Sbjct: 38 GAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSEDSVLAAIEA 97 Query: 237 EGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVG 274 QLG + G + G+ +G Sbjct: 98 ANQLGRLRYAVVAHGG----FGVAQRIVQRDGSPADMG 131 >1VH3-A nrPDB Length = 262 Score = 32.3 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 21/51 (41%), Gaps = 5/51 (9%) Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVL-----QISKESPQEIARKVE 237 A GA++V++ + AK GA++ + E E+ K+ Sbjct: 37 ALQSGASRVIIATDNENVADVAKSFGAEVCMTSVNHNSGTERLAEVVEKLA 87 >1JWB-B nrPDB Length = 249 Score = 32.3 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 13/33 (39%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLS 206 +VL+ G G +G + G + + D Sbjct: 32 SRVLIVGLGGLGCAASQYLASAGVGNLTLLDFD 64 >6APH-A nrPDB Length = 445 Score = 32.3 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 3/84 (3%) Query: 161 GIHACRRGG--VTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGA 218 + A RR + G +V+VCG G +G T + G + V VT++ +A G Sbjct: 212 AVDAIRRATDVMLAGKRVVVCGFGDVGKGTAASFRGAG-SIVTVTEIDPICALQAAMEGY 270 Query: 219 DLVLQISKESPQEIARKVEGQLGC 242 ++ + +I G G Sbjct: 271 EVKQLDTVVDNADIIITTTGNFGI 294 >3GDH-A nrPDB Length = 241 Score = 32.3 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 13/89 (14%), Positives = 33/89 (37%), Gaps = 4/89 (4%) Query: 128 NLCRFYKHNAAFCYKLPDNVTFEEGA--LIEPLSVGIHACRRGGVTLGHKVLVCGAGPIG 185 L +++ + D + + + P + H R + V+V +G Sbjct: 31 ELAKYWAQRYRLFSRFDDGIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVG 90 Query: 186 MVTLLVAKAMGAAQVVVTDLSATRLSKAK 214 T+ A + +V+ D+ +++ A+ Sbjct: 91 GNTIQFA--LTGMRVIAIDIDPVKIALAR 117 >3KTC-A nrPDB Length = 333 Score = 32.3 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 36/87 (41%), Gaps = 16/87 (18%) Query: 18 GDLRLENYPIP-EPGPNEVLLR-------MHSVGICGSDVHYWEYGRIGNFIVKKP---- 65 G+L + P P PG ++ + ++GI + Y + G F P Sbjct: 46 GELSYVDLPYPFTPGVTLSEVKDALKDAGLKAIGI--TPEIYLQKWSRGAFTNPDPAARA 103 Query: 66 --MVLGHEASGTVEKVGSSVKHLKPGD 90 L HE++G V ++G++ + PG Sbjct: 104 AAFELMHESAGIVRELGANYVKVWPGQ 130 >5XW3-A nrPDB Length = 315 Score = 32.3 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 28/166 (16%), Positives = 56/166 (33%), Gaps = 26/166 (15%) Query: 164 ACRRGGVTLGHKVL--VCGAGPIGMVTLLVAKAMGAAQVVVTDLSA---TRLSKAKEIGA 218 A +G VT G ++ G IG+ + + +V+V + K +GA Sbjct: 55 ALEKGLVTEGGTIIEPTAGNTGIGLALAALQHDL---RVIVCVPEKFSIEKQELMKALGA 111 Query: 219 DLVLQISKESPQEIARKVEGQLGCKPE-VTIECTGAEASIQAGIYATRSGGNLVLVGLGS 277 +V +++ K + + P + EA+ +A Sbjct: 112 TVVHTPTEQGMTGAIAKAKELVNEIPNSYSPSQFANEANPRAYFKTLGP----------- 160 Query: 278 EMTTVPLLHAAIREVDIK-GVFRYCNTWPVAISMLASKSVNVKPLV 322 L A E++I T+ S L K++++K ++ Sbjct: 161 -----ELWSALNGEINIFVAGAGTGGTFMGTASYLKEKNIDIKTVI 201 >3OND-A nrPDB Length = 488 Score = 31.9 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 47/128 (36%), Gaps = 20/128 (15%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQE 231 G +V G G +G K GA +V+VT++ LQ + E Q Sbjct: 264 AGKVAVVAGYGDVGKGCAAALKQAGA-RVIVTEIDPIC-----------ALQATMEGLQV 311 Query: 232 IARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHA---- 287 + + + ++ + TG + I + + N ++ +G + +L Sbjct: 312 L---TLEDVVSEADIFVTTTGNKDIIMLD-HMKKMKNNAIVCNIGHFDNEIDMLGLETHP 367 Query: 288 AIREVDIK 295 ++ + IK Sbjct: 368 GVKRITIK 375 >1KR5-A nrPDB Length = 226 Score = 31.9 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 27/127 (21%), Positives = 46/127 (36%), Gaps = 20/127 (15%) Query: 169 GVTLGHKVLVCGAGPIGMVTLLVAKAMG-AAQVVVTDLSATRLSKAKEIGADLVLQISKE 227 + G K L G+G + A+ +G +V+ D KE+ D V + K+ Sbjct: 74 QLHEGAKALDVGSGSGILTAC-FARMVGCTGKVIGID-------HIKELVDDSVNNVRKD 125 Query: 228 SPQEIAR-KVEGQLGCK---------PEVTIECTGAEASIQAGIYATRSGGNLVL-VGLG 276 P ++ +V+ +G + A QA I + GG L+L VG Sbjct: 126 DPTLLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPA 185 Query: 277 SEMTTVP 283 + Sbjct: 186 GGNQMLE 192 >3EGI-A nrPDB Length = 206 Score = 31.9 bits (71), Expect = 0.45, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 19/39 (48%), Gaps = 2/39 (5%) Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAK 214 V+V +G T+ A + +V+ D+ +++ A+ Sbjct: 46 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 82 >5UOG-A nrPDB Length = 344 Score = 31.9 bits (71), Expect = 0.47, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 44/128 (34%), Gaps = 23/128 (17%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 G V + G G IG+ +A G + + + + +G Sbjct: 164 GRTVGLFGLGRIGLAIARRLEAFGVS-IAYHTRTPR-----EGLGFTY------------ 205 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQA----GIYATRSGGNLVLVGLGSEMTTVPLLHAA 288 + G + + G ++++A + A G L+ VG GS + L+ A Sbjct: 206 HPTLVGMAEAVDTLIVIVPGTASTLKAVNADVLSALGPKGVLINVGRGSTVDEAALVT-A 264 Query: 289 IREVDIKG 296 ++ I G Sbjct: 265 LQNGTIAG 272 >2EKL-A nrPDB Length = 313 Score = 31.9 bits (71), Expect = 0.49, Method: Composition-based stats. Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 2/50 (4%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 221 G + + G G IG ++A AMG +V+ D+ R KA++I A V Sbjct: 141 AGKTIGIVGFGRIGTKVGIIANAMGM-KVLAYDILDIR-EKAEKINAKAV 188 >1J6U-A nrPDB Length = 469 Score = 31.5 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 9/55 (16%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 178 VCGAGPIGMVTLLVAKAMGAAQVVVTDLSA-TRLSKAKEIGADLVLQISKESPQE 231 G G IGM + + + V +++ R + +++G + + S ++ + Sbjct: 17 FVGIGGIGMSAVALHEFSNGNDVYGSNIEETERTAYLRKLGIPIFVPHSADNWYD 71 >6MAT-A nrPDB Length = 813 Score = 31.5 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 22/73 (30%) Query: 219 DLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSE 278 D + S + +++G I T I I G + VGL S Sbjct: 612 DSLSDASARVVNTLLTELDGVGDRSGIYVIGATNRPDMIDEAIRRPGRLGTSIYVGLPSA 671 Query: 279 MTTVPLLHAAIRE 291 V +L R Sbjct: 672 EDRVKILKTLYRN 684 >2YYZ-A nrPDB Length = 359 Score = 31.5 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 14/96 (14%) Query: 13 VVHGPGDLRLENYPIPEPGPNEVLLRMHSVGI----CGSDVHYWEYGRIGNFIVKKPMVL 68 V + L+ ++ I P P +V L+ VGI C E G V +P L Sbjct: 249 VENKQTILKRDDVIIKLPEPVDVKLKEVVVGIRPEHCRISRERVENSIPGVVYVVEP--L 306 Query: 69 GHEAS-------GTVEKV-GSSVKHLKPGDRVAIEP 96 G + G + KV G + K +PG+ V + P Sbjct: 307 GRDIIVNVKTEKGEIIKVFGDTGKAPQPGENVFLVP 342 >2EEZ-A nrPDB Length = 369 Score = 31.5 bits (70), Expect = 0.59, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 44/100 (44%), Gaps = 6/100 (6%) Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEI--GADLVLQISKESPQEI 232 V++ G G +G +A MGA QV + D++ RL ++ G + L ++ + ++ Sbjct: 168 SVVILGGGTVGTNAAKIALGMGA-QVTILDVNHKRLQYLDDVFGGRVITLTATEANIKKS 226 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVL 272 + + +G V + A + + + G +++ Sbjct: 227 VQHADLLIGA---VLVPGAKAPKLVTRDMLSLMKEGAVIV 263 >4EJ0-A nrPDB Length = 342 Score = 31.5 bits (70), Expect = 0.59, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 31/83 (37%), Gaps = 3/83 (3%) Query: 175 KVLVCGAGP-IGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIA 233 ++V GA IG + G +++ D + TR K K + D + + + + Sbjct: 14 TLIVTGAAGFIGANLVKALNERGETRIIAVD-NLTRADKFKNL-VDCEIDDYLDKTEFVE 71 Query: 234 RKVEGQLGCKPEVTIECTGAEAS 256 R G G V E ++ Sbjct: 72 RFARGDFGKVRAVFHEGACSDTM 94 >3F9I-A nrPDB Length = 249 Score = 31.5 bits (70), Expect = 0.59, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 25/59 (42%), Gaps = 10/59 (16%) Query: 172 LGHKVLVCGAG-PIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESP 229 G L+ GA IG + +G ++V+++ + +L K +G K++ Sbjct: 13 TGKTSLITGASSGIGSAIARLLHKLG-SKVIISGSNEEKL---KSLG-----NALKDNY 62 >3AOE-A nrPDB Length = 424 Score = 31.5 bits (70), Expect = 0.60, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 30/86 (34%), Gaps = 12/86 (13%) Query: 158 LSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIG 217 ++ A + G G +V + G G +G GA V V D + T Sbjct: 204 ITAAAAAEKIGLQVEGARVAIQGFGNVGNAAARAFHDHGARVVAVQDHTGT--------- 254 Query: 218 ADLVLQISKESPQEIARKVEGQLGCK 243 V + P ++ R V+ G + Sbjct: 255 ---VYNEAGIDPYDLLRHVQEFGGVR 277 >6GBN-A nrPDB Length = 438 Score = 31.5 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 16/115 (13%), Positives = 41/115 (35%), Gaps = 16/115 (13%) Query: 170 VTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESP 229 + G +V G G +G + + GA +V+VT++ +A Sbjct: 216 MMAGKVAVVAGYGDVGKGSAASLRGAGA-RVIVTEIDPICALQA------------AMDG 262 Query: 230 QEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL 284 E+ + + + ++ + TG + I + +++ +G + + Sbjct: 263 YEVKKMADAVK--RADIVVTATGNKNIITGEHFKAMRD-KVIVCNIGHFDNEIDM 314 >4IZO-A nrPDB Length = 419 Score = 31.5 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 40/117 (34%), Gaps = 5/117 (4%) Query: 157 PLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEI 216 P S+ + G + + G G +G + A+AMG +V V D T + A Sbjct: 19 PGSMTALPNPNSPILPGAWLGMVGGGQLGRMFCFAAQAMG-YRVAVLDPDPTSPAGAV-- 75 Query: 217 GADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLV 273 AD L+ + + +A + E + + + G V + Sbjct: 76 -ADKHLRAAYDDEAALAELAQLCDAVSTEFENVPAASLDFLAQSTF-VAPAGRCVAI 130 >4BUB-A nrPDB Length = 498 Score = 31.5 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 18/122 (14%), Positives = 41/122 (33%), Gaps = 30/122 (24%) Query: 169 GVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRL----SKAKEIGADLVL-- 222 ++ G ++V GAG + + A ++ AD+V+ Sbjct: 361 KISQGRVIVVFGAGG--------------------NSDRGKRPMMSEVASKL-ADVVILT 399 Query: 223 --QISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMT 280 E P++I + + + + +I+ + G ++V+ G G E Sbjct: 400 TDDPRGEDPEQIMEDLIKGIDKRKPYLVLF-DRREAIETALTIANRGDSVVIAGRGHERY 458 Query: 281 TV 282 + Sbjct: 459 QI 460 >3NJ4-A nrPDB Length = 435 Score = 31.5 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 20/45 (44%), Gaps = 2/45 (4%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSA-TRLSKAKE 215 G +V G G +G + GA +V++T++ L A E Sbjct: 215 AGKVAVVAGYGDVGKGCAQALRGFGA-RVIITEIDPINALQAAME 258 >6DHM-A nrPDB Length = 582 Score = 31.5 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 20/130 (15%), Positives = 38/130 (29%), Gaps = 12/130 (9%) Query: 79 VGSSVKHLKPGDRVAIEPGAPRENDEFC-KMGRYNLSPSIFFCATPPDDGNLCRFYKHNA 137 +G V P D E D + +G Y+++ P G + Sbjct: 239 IGPGVDVPAP-DMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATG 297 Query: 138 AFCYK-LPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMG 196 + + + + I ++ G V G G +G+ ++ G Sbjct: 298 RGVFHGIENFINEASYMSILGMTPGFG---------DKTFAVQGFGNVGLHSMRYLHRFG 348 Query: 197 AAQVVVTDLS 206 A V V + Sbjct: 349 AKCVAVGESD 358 >6CU3-A nrPDB Length = 336 Score = 31.1 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 30/75 (40%), Gaps = 5/75 (6%) Query: 177 LVCGAGPIGMVTLLVAKAMGAAQVVVT---DLSATRLSKAKEIGADLVLQISKESPQEIA 233 +V G + L A GA +V+ D+ + G V+++ K ++IA Sbjct: 54 VVLDIGCGTGILCLFAAKAGAKRVIGIDMSDIIDKARQIVSDNGYSHVIELIKGKVEDIA 113 Query: 234 RKVEGQLGCKPEVTI 248 + G K ++ I Sbjct: 114 QLPFGIE--KVDIII 126 >4K28-A nrPDB Length = 269 Score = 31.1 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 24/54 (44%), Gaps = 2/54 (3%) Query: 164 ACRRGGVTLGHKVLVCGAGPIGMVTLLVAKA-MGAAQVVVTDLSATRLSKAKEI 216 A + G G + LV G G +G + A A G A + + D S R+ E+ Sbjct: 116 AHKHGFEPAGKRALVIGCGGVG-SAIAYALAEAGIASITLCDPSTARMGAVCEL 168 >1JG3-A nrPDB Length = 235 Score = 31.1 bits (69), Expect = 0.69, Method: Composition-based stats. Identities = 24/177 (13%), Positives = 49/177 (27%), Gaps = 21/177 (11%) Query: 129 LCRFYKHNAAF--CYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGM 186 R+ + + + + G + + + G +L G G Sbjct: 46 YPRYLSVEDKYKKYAHIDEPLPIPAGQTVSAPHMVAIMLEIANLKPGMNILEVGTGSGWN 105 Query: 187 VTL--LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKP 244 L + K V + + AK + + + + + P Sbjct: 106 AALISEIVK----TDVYTIERIPELVEFAKR-------NLERAGVKNVHVILGDGSKGFP 154 Query: 245 -----EVTIECTGAEASIQAGIYATRSGGNLVL-VGLGSEMTTVPLLHAAIREVDIK 295 +V I GA + I + GG L++ VG + + + IK Sbjct: 155 PKAPYDVIIVTAGAPKIPEPLIEQLKIGGKLIIPVGSYHLWQELLEVRKTKDGIKIK 211 >6F3O-A nrPDB Length = 472 Score = 31.1 bits (69), Expect = 0.71, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 37/103 (35%), Gaps = 2/103 (1%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 G + LV G G +G + + G V V ++ +A G ++V Sbjct: 224 GKQALVIGYGDVGKGSSQSLRQEGM-IVKVAEVDPICAMQACMDGFEVVSPYKNGINDGT 282 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQAG-IYATRSGGNLVLVG 274 ++ L K ++ + TG A + A + + +G Sbjct: 283 EASIDAALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIG 325 >2AS0-A nrPDB Length = 396 Score = 31.1 bits (69), Expect = 0.73, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 37/110 (33%), Gaps = 27/110 (24%) Query: 170 VTLGHKVL--VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKE 227 V G +VL G + A GA +V+ D S + AKE Sbjct: 215 VQPGDRVLDVFTYTGG---FAIHAA-IAGADEVIGIDKSPRAIETAKE-------NAKLN 263 Query: 228 SPQEIARKVEG----------QLGCKPEVTI----ECTGAEASIQAGIYA 263 ++ + + G + G K ++ + E ++AG+ A Sbjct: 264 GVEDRMKFIVGSAFEEMEKLQKKGEKFDIVVLDPPAFVQHEKDLKAGLRA 313 >3X43-A nrPDB Length = 332 Score = 31.1 bits (69), Expect = 0.76, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Query: 158 LSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVT--DLSATRLSKAKE 215 LSV + A +G + G ++ C +G +G+ +VA A G V V S R + Sbjct: 48 LSVVLDAEAKGLLKPGDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRA 107 Query: 216 IGADLVL 222 G LVL Sbjct: 108 YGGKLVL 114 >2BRY-A nrPDB Length = 497 Score = 31.1 bits (69), Expect = 0.78, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 19/38 (50%) Query: 165 CRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVV 202 ++G K LV GAGP G+ + +GA V+V Sbjct: 84 YQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 121 >4TXK-A nrPDB Length = 615 Score = 31.1 bits (69), Expect = 0.78, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 19/38 (50%) Query: 165 CRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVV 202 ++G K LV GAGP G+ + +GA V+V Sbjct: 76 YQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 113 >1QO8-A nrPDB Length = 566 Score = 31.1 bits (69), Expect = 0.79, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 18/35 (51%) Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVV 202 G + +VLV GAG G L AK GA ++V Sbjct: 116 AGPSETTQVLVVGAGSAGFNASLAAKKAGANVILV 150 >5IJZ-A nrPDB Length = 447 Score = 30.7 bits (68), Expect = 0.87, Method: Composition-based stats. Identities = 25/135 (18%), Positives = 46/135 (34%), Gaps = 11/135 (8%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLS-----ATRLSKAKEIGADLV----LQ 223 G K++V G+G + + A+ +GA + +D S + AK V + Sbjct: 233 GQKIIVSGSGNVATYAIEKAQELGATVIGFSDSSGWVHTPNGVDVAKLREIKEVRRARVS 292 Query: 224 ISKESPQEIARKVEGQ-LGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTV 282 + + + +G K ++ + C G V G+ M + Sbjct: 293 VYADEVEGATYHTDGSIWDLKCDIALPCATQNELNGENAKTLADNG-CRFVAEGANMPST 351 Query: 283 PLLHAAIREVDIKGV 297 P RE DI+ Sbjct: 352 PEAVEVFRERDIRFG 366 >5NMX-A nrPDB Length = 425 Score = 30.7 bits (68), Expect = 0.90, Method: Composition-based stats. Identities = 9/22 (40%), Positives = 11/22 (50%) Query: 175 KVLVCGAGPIGMVTLLVAKAMG 196 +V V GAGP G+ K G Sbjct: 3 RVAVLGAGPSGLTAARYLKQAG 24 >5T5Q-A nrPDB Length = 247 Score = 30.7 bits (68), Expect = 0.96, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 31/85 (36%), Gaps = 8/85 (9%) Query: 175 KVLVCGA-GPIGMVTLLVAKAMGAAQVVVTDLSATRLS-KAKEIG-----ADLVLQISKE 227 +++ GA G IG + A GA +V+TDL L A +G A + S Sbjct: 11 TLVLTGANGGIGRAIAELFHASGA-NLVLTDLDREGLDAFAASLGSPERIATIKADASSA 69 Query: 228 SPQEIARKVEGQLGCKPEVTIECTG 252 E + + + + G Sbjct: 70 DDAEKTVALAMERFGGIDFLVPSAG 94 >5TQV-A nrPDB Length = 233 Score = 30.7 bits (68), Expect = 0.98, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 34/83 (40%), Gaps = 7/83 (8%) Query: 174 HKVLVCGAG-PIGMVTL-LVAKAMGAAQVVVTDLSATRLSKAKEIGAD-LVLQISKESPQ 230 VL+ GA +G + + V+ T L+ + +GA L I++ P+ Sbjct: 10 KTVLIVGASRGLGREFVRQYQR--DGWNVIATARDDASLAALRALGAHAHALDITQ--PE 65 Query: 231 EIARKVEGQLGCKPEVTIECTGA 253 +IA G + +V + +G Sbjct: 66 QIAALGWKLDGERLDVAVVVSGV 88 >3BKW-A nrPDB Length = 243 Score = 30.7 bits (68), Expect = 0.98, Method: Composition-based stats. Identities = 28/172 (16%), Positives = 52/172 (30%), Gaps = 17/172 (9%) Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248 A GA+ V+ DLS L++A+ G D + + ++ + + + Sbjct: 58 CRWAHEHGASYVLGLDLSEKMLARARAAGPDTGITYERADLDKLHLPQDSFDLAYSSLAL 117 Query: 249 ECTGAEASIQAGI-YATRSGGNLVL-----VGLGSEMTTVPLLHAAIREVDIKGVFRYCN 302 A + + A GG+ V + + + R I RY Sbjct: 118 HYVEDVARLFRTVHQALSPGGHFVFSTEHPIYMAPARPGWAIDAEGRRTWPID---RYLV 174 Query: 303 TWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSD 354 P LA V V + G ++ + + P+D Sbjct: 175 EGPRKTDWLAKGVVKHHRTVGTTLN--------ALIRSGFAIEHVEEFCPTD 218 >4RL6-A nrPDB Length = 427 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 26/181 (14%), Positives = 56/181 (30%), Gaps = 15/181 (8%) Query: 174 HKVLVCGAGPIGMVTL-LVAK-AMGAAQVVVTDLSATRLS--KAKEIGADLV-LQISKES 228 ++LV G G + V + + + + ++++ + ++ KAK G ++ + Sbjct: 2 SRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLKAKLEGKTSTKIETAALD 61 Query: 229 PQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGN-LVLVGLGSEMTTVPLLHA 287 ++ + KPE + + +G + + +E T P A Sbjct: 62 ADKVEEVIALIGSYKPEAVLNVALPYQDLTIMDACLATGVHYIDTANYEAEDTEDPEWRA 121 Query: 288 AI----REVDIKGVFRYCNTWPVAISMLASK-----SVNVKPLVTHRFPLEKALEAFETF 338 +E+ F Y W + P VT F F+ Sbjct: 122 IYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSGFDPGVTSVFSAYALKHYFDEI 181 Query: 339 K 339 Sbjct: 182 H 182 >1DL5-A nrPDB Length = 317 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 43/109 (39%), Gaps = 12/109 (11%) Query: 169 GVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRL-SKAKE----IGADLVLQ 223 G+ G +VL G G G ++++ +G +VV+ + ++ AK +G + V+ Sbjct: 72 GLDKGMRVLEIG-GGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVERLGIENVIF 130 Query: 224 ISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVL 272 + + + +V G + + + GG +++ Sbjct: 131 VCGDGYYGVPE------FSPYDVIFVTVGVDEVPETWFTQLKEGGRVIV 173 >4V61-BD nrPDB Length = 352 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 30/82 (36%), Gaps = 7/82 (8%) Query: 187 VTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEV 246 T+ + K G + ++ +AK GAD+V +E+ +++G + Sbjct: 175 ATVSLPKGTGKTVKIAVLAQGDKIDEAKAAGADIV------GGEELIEQIKGGF-MDFDK 227 Query: 247 TIECTGAEASIQAGIYATRSGG 268 I + A + + G Sbjct: 228 LIATSDMMAKVASLGRILGPRG 249 >3LLV-A nrPDB Length = 141 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 28/64 (43%), Gaps = 5/64 (7%) Query: 177 LVCG--AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 234 +V G A +G+ + A G +V+ D S ++ ++ G D V+ + + Sbjct: 10 IVIGSEAAGVGL--VRELTAAG-KKVLAVDKSKEKIELLEDEGFDAVIADPTDESFYRSL 66 Query: 235 KVEG 238 +EG Sbjct: 67 DLEG 70 >4FHN-X nrPDB Length = 450 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 25/63 (39%), Gaps = 8/63 (12%) Query: 152 GALIEPLSVGIHAC--------RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVT 203 G+LI P + G R G G +V V G+G + + A GA + + Sbjct: 206 GSLIRPEATGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITAS 265 Query: 204 DLS 206 D S Sbjct: 266 DSS 268 >1CRW-G nrPDB Length = 333 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 27/127 (21%), Positives = 41/127 (32%), Gaps = 19/127 (14%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDL-----------------SATRLSKAKEI 216 K+ + G G IG + L A MGA V V D + E Sbjct: 1 SKIGINGFGRIGRLVLRAALEMGAQVVAVNDPFIALEYMVYMFKYDSTHGMFKGEVKAED 60 Query: 217 GADLVLQISKESPQEIARKVEGQLG-CKPEVTIECTGAEASIQAGIYATRSGGNLVLVGL 275 GA LV+ K + + E +E TG +I+ + G V++ Sbjct: 61 GA-LVVDGKKITVFNEMKPENIPWSKAGAEYIVESTGVFTTIEKASAHFKGGAKKVIISA 119 Query: 276 GSEMTTV 282 S + Sbjct: 120 PSADAPM 126 >6J0Z-C nrPDB Length = 491 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIG 217 V+V GAGP G++ + G + VVV D A + +++ +G Sbjct: 6 SDVVVVGAGPTGLMLAGELRLAGVS-VVVLDKLAEPIKESRALG 48 >4YRY-B nrPDB Length = 468 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 20/46 (43%) Query: 170 VTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE 215 + +G KV V GAG M A +GA +V + R A+ Sbjct: 276 IRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARR 321 >3N58-A nrPDB Length = 464 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Query: 170 VTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESP 229 + G +VCG G +G + GA +V VT++ +A G ++V S Sbjct: 244 MMAGKVAVVCGYGDVGKGSAQSLAGAGA-RVKVTEVDPICALQAAMDGFEVVTLDDAAST 302 Query: 230 QEIARKVEGQLGC 242 +I G Sbjct: 303 ADIVVTTTGNKDV 315 >1O54-A nrPDB Length = 277 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 44/282 (15%), Positives = 77/282 (27%), Gaps = 68/282 (24%) Query: 79 VGSSVKHLKPGDRVAI--------------------EPGAPRENDEFCKMGRYNLSPSIF 118 VG LKPGDRV + G N+ F K + S Sbjct: 13 VGKVADTLKPGDRVLLSFEDESEFLVDLEKDKKLHTHLGIIDLNEVFEKGPGEIIRTSAG 72 Query: 119 FCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLV 178 + P + +F L V G +++ Sbjct: 73 KKGYILIPSLIDEIMNMKRRTQIVYPKDSSFIAMML--------------DVKEGDRIID 118 Query: 179 CGAGPIGMVTLLVAKAMGAA-QVVVTDLSATRLSKAKEIGADLVLQISKESPQEI----A 233 G G M + +A+A+G++ +V + A+ ++K E Sbjct: 119 TGVGSGAMCAV-LARAVGSSGKVFAYEKREEFAKLAES-------NLTKWGLIERVTIKV 170 Query: 234 RKVEGQLGCK--PEVTIECTGAEASIQAGIYATRSGGNLVLV--------GLGSEMTTVP 283 R + K + ++ I A + GG V ++ +P Sbjct: 171 RDISEGFDEKDVDALFLDVPDPWNYIDKCWEALKGGGRFATVCPTTNQVQETLKKLQELP 230 Query: 284 LLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHR 325 + + E +FR P + V +V H Sbjct: 231 FIRIEVWE----SLFRPYKPVPERLR-------PVDRMVAHT 261 >6ABI-A nrPDB Length = 358 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 7/50 (14%), Positives = 15/50 (30%), Gaps = 2/50 (4%) Query: 198 AQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVT 247 +++ D+ K+ GAD + + L +V Sbjct: 27 TKIIFFDIKDYDKEFFKKYGADY--NFEMTFLKVRLTEETANLTKGYDVV 74 >1MV8-A nrPDB Length = 436 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 34/89 (38%), Gaps = 10/89 (11%) Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 234 ++ + G G +G + +V+ D+S+T++ G +++ E+ + R Sbjct: 2 RISIFGLGYVG-AVCAGCLSARGHEVIGVDVSSTKIDLI-NQGKSPIVEPGLEALLQQGR 59 Query: 235 KVEGQLGCKP--------EVTIECTGAEA 255 + G +V+ C G + Sbjct: 60 QTGRLSGTTDFKKAVLDSDVSFICVGTPS 88 >3GDF-A nrPDB Length = 267 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 42/113 (37%), Gaps = 13/113 (11%) Query: 173 GHKVLVCGAGPIGMVTLLVAKA---MGAAQVVVTDLSAT-RLSKAKEIGADLVLQI---- 224 G V+V GA + + A+ MGAA + A KE+ ++ Sbjct: 20 GKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKAYK 79 Query: 225 ----SKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLV 273 S ES +++ + V G + + I GA A + + ++V V Sbjct: 80 CQVDSYESCEKLVKDVVADFG-QIDAFIANAGATADSGILDGSVEAWNHVVQV 131 >1L1F-A nrPDB Length = 505 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 13/100 (13%), Positives = 31/100 (31%), Gaps = 10/100 (10%) Query: 108 MGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYK-LPDNVTFEEGALIEPLSVGIHACR 166 +G Y+++ P G + + + + + I ++ G Sbjct: 191 IGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG--- 247 Query: 167 RGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLS 206 +V G G +G+ ++ GA + V + Sbjct: 248 ------DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESD 281 >3KYD-B nrPDB Length = 551 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 17/41 (41%) Query: 166 RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLS 206 G +VLV GAG IG L G + + + DL Sbjct: 12 ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 52 >3JTM-A nrPDB Length = 351 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 26/73 (35%), Gaps = 5/73 (6%) Query: 158 LSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIG 217 + A G + GAG IG + L K G ++ D KE G Sbjct: 153 AGIAYRAYDL----EGKTIGTVGAGRIGKLLLQRLKPFG-CNLLYHDRLQMAPELEKETG 207 Query: 218 ADLVLQISKESPQ 230 A V +++ P+ Sbjct: 208 AKFVEDLNEMLPK 220 >3KYC-B nrPDB Length = 660 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 17/41 (41%) Query: 166 RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLS 206 G +VLV GAG IG L G + + + DL Sbjct: 30 ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 70 >3JTJ-A nrPDB Length = 253 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 31/85 (36%), Gaps = 2/85 (2%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQI--SKESP 229 G + P+ + + A A GA +V+V + + G ++ L + Sbjct: 20 PGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGT 79 Query: 230 QEIARKVEGQLGCKPEVTIECTGAE 254 + +A +E ++ + G E Sbjct: 80 ERLAEVIEHYGFADDDIIVNVQGDE 104 >3HG7-A nrPDB Length = 324 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 35/117 (29%), Gaps = 13/117 (11%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 G +L+ G G IG K G + V+ R G D V Q+ Sbjct: 140 GRTLLILGTGSIGQHIAHTGKHFGMKVLGVSRSGRERA------GFDQVYQLP------A 187 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQAG-IYATRSGGNLVLVGLGSEMTTVPLLHAA 288 K+ Q V A + G L VG G+ + LL A Sbjct: 188 LNKMLAQADVIVSVLPATRETHHLFTASRFEHCKPGAILFNVGRGNAINEGDLLTAL 244 >1HL3-A nrPDB Length = 358 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 12/24 (50%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMG 196 G + + G G +G L AKA G Sbjct: 171 GETLGIIGLGRVGQAVALRAKAFG 194 >2YFH-A nrPDB Length = 448 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 30/145 (20%), Positives = 48/145 (33%), Gaps = 23/145 (15%) Query: 152 GALIEPLSVGIHAC--------RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVT 203 G+LI P + G R G G +V V G+G + + A GA + + Sbjct: 202 GSLIRPEATGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITAS 261 Query: 204 DLS----------ATRLSKAKEIGAD---LVLQISKESPQEIARKVEGQLGCKPEVTIEC 250 D S +L++ EI A V +KE + ++ + C Sbjct: 262 DSSGTVVDESGFTKEKLARLIEIKASRDGRVADYAKEFGLVYLEG-QQPWSLPVDIALPC 320 Query: 251 TG-AEASIQAGIYATRSGGNLVLVG 274 E + A +G V G Sbjct: 321 ATQNELDVDAAHQLIANGVKAVAEG 345 >5MGZ-A nrPDB Length = 236 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 30/177 (16%), Positives = 58/177 (32%), Gaps = 25/177 (14%) Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADL--VLQIS 225 G+ G V+ G + +L ++ + +V DLS + A+E A+ L+ Sbjct: 35 AGIADGQTVVDLCCGSGELEVILSSR-FPSLNLVGVDLSEDMVRIAREYAAEQGKALEFR 93 Query: 226 KESPQEIARKVEGQLGCKPEVTIE------CTGAEASIQAGIYATRSGGNLVLVGLGSEM 279 Q +A + L K ++ + T A+ + + GG ++ + Sbjct: 94 HGDAQLLAGMED--LAGKADLVVSRNAFHRLTRLPAAFDTMLRLAKPGGAVLNCSF---I 148 Query: 280 TTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFP-LEKALEAF 335 + R R ++ + LA H P L+ EA Sbjct: 149 HPSDFDESGFRAWVTFLNQRPWDSEMQIVWALAH----------HYAPRLDDYREAL 195 >3H9U-A nrPDB Length = 436 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 20/45 (44%), Gaps = 2/45 (4%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSA-TRLSKAKE 215 G VCG G +G + GA +VVVT++ L A E Sbjct: 210 AGKTACVCGYGDVGKGCAAALRGFGA-RVVVTEVDPINALQAAME 253 >4WJI-A nrPDB Length = 293 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 41/123 (33%), Gaps = 9/123 (7%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMG-AAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 + + G G IG + A +VVT S L +A E+G + Sbjct: 5 QTIALIGIGLIGSSIARDIREKQLAGTIVVTTRSEATLKRAGELG------LGDRYTLSA 58 Query: 233 ARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREV 292 A VEG V + +GA A+ A + G + VG + ++V Sbjct: 59 AEAVEGADLVVVSVPVGASGAVAAEIAA--HLKPGAIVTDVGSTKGSVIAQMAPHLPKDV 116 Query: 293 DIK 295 Sbjct: 117 HFV 119 >3NNK-A nrPDB Length = 411 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 15/34 (44%) Query: 160 VGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAK 193 GI A + G KVLV G G + +A+ Sbjct: 75 AGIEAILVSAIRPGDKVLVPVFGRFGHLLCEIAR 108 >2D1F-A nrPDB Length = 360 Score = 29.6 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 42/121 (34%), Gaps = 13/121 (10%) Query: 151 EGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTL-LVAKA-MGAAQVVVTDLS-A 207 L + G V P G + + +A+A M A+++ D + Sbjct: 86 RAVLCASTGNTSASAAAYAARAGITCAV--LIPQGKIAMGKLAQAVMHGAKIIQIDGNFD 143 Query: 208 TRLSKAKEIGADL--------VLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQA 259 L A+++ AD V + E + A ++ LG P+V G +I A Sbjct: 144 DCLELARKMAADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNITA 203 Query: 260 G 260 Sbjct: 204 Y 204 >3HDH-A nrPDB Length = 302 Score = 29.2 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE 215 V V G G +G VA A G VV+ D + L+K+K+ Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK 56 >3K8D-A nrPDB Length = 264 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 30/74 (40%), Gaps = 2/74 (2%) Query: 210 LSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGN 269 L +A+E GA+ ++ + +++AR VE G + + + + Sbjct: 50 LERARESGAERIIVAT--DHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDD 107 Query: 270 LVLVGLGSEMTTVP 283 V+V + + +P Sbjct: 108 TVIVNVQGDEPMIP 121 >5AOV-A nrPDB Length = 336 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 18/48 (37%), Gaps = 2/48 (4%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADL 220 G + + G G IG AK ++ + KE+GA+ Sbjct: 150 GKTIGIVGFGRIGQAIARRAKGFNMR--ILYYSRTRKSQAEKELGAEY 195 >5B37-A nrPDB Length = 361 Score = 29.2 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 24/52 (46%), Gaps = 6/52 (11%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQV--VVTDLSATRLSKAKEI-GADLV 221 G KV V G G +G + + + V V+D+ + + K + GA +V Sbjct: 169 GMKVAVQGLGNVGKN---LCRHLHEHDVQLFVSDVDPIKAEEVKRLFGATVV 217 >6HNS-A nrPDB Length = 454 Score = 29.2 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 14/27 (51%), Gaps = 3/27 (11%) Query: 175 KVLVCGAGPIGMV---TLLVAKAMGAA 198 +V + GAGP G+ A A GAA Sbjct: 4 RVAIIGAGPCGLAQLRAFQSAAAKGAA 30 >4PZE-A nrPDB Length = 284 Score = 29.2 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 48/146 (32%), Gaps = 13/146 (8%) Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGA---DLVLQISKESPQE 231 V + GAG +G +G VV+ D+S + K A D +++ K + + Sbjct: 5 TVGIVGAGTMGNGIAQACAVVGL-NVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEAD 63 Query: 232 IARKVEGQLGCKP-------EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPL 284 A + G ++ IE ++ I G V + S +++ + Sbjct: 64 KASALARIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENVIIASNTSSISI 123 Query: 285 LHA--AIREVDIKGVFRYCNTWPVAI 308 D + N PV Sbjct: 124 TKLAAVTSRADRFIGMHFFNPVPVMA 149 >1F14-A nrPDB Length = 310 Score = 29.2 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKE 215 V V G G +G VA A G VV+ D + L+K+K+ Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK 56 >4LRT-B nrPDB Length = 323 Score = 29.2 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 44/103 (42%), Gaps = 13/103 (12%) Query: 173 GHKVL-VCGAGPIG---MVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKES 228 G V + G G IG ++ L ++ + +V D ++ L++A+++G ++ S E Sbjct: 22 GKAVAAIVGPGNIGTDLLIKLQRSEHIEVRYMVGVDPASEGLARARKLG----VEASAEG 77 Query: 229 PQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLV 271 + + P++ E T A+A + +G + Sbjct: 78 VDWLLEQ-----DELPDLVFEATSAKAHLANAPRYAEAGITAI 115 >4DIM-A nrPDB Length = 403 Score = 29.2 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 29/65 (44%), Gaps = 3/65 (4%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIA 233 ++L+ GAG + AK +G + T +A + AD + + +P E+ Sbjct: 8 KRLLILGAGRGQLGLYKAAKELGIHTIAGTMPNAHKPCLNL---ADEISYMDISNPDEVE 64 Query: 234 RKVEG 238 +KV+ Sbjct: 65 QKVKD 69 >3FEO-A nrPDB Length = 437 Score = 28.8 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 12/29 (41%) Query: 42 VGICGSDVHYWEYGRIGNFIVKKPMVLGH 70 ICGSD+H + + P + H Sbjct: 93 CNICGSDIHPVGWCAASGKPLVPPRTIQH 121 >3DC2-A nrPDB Length = 529 Score = 28.8 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 12/29 (41%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVV 201 G V V G G IG + A GA V Sbjct: 142 GKTVGVVGLGRIGQLVAQRIAAFGAYVVA 170 >5Y0R-A nrPDB Length = 425 Score = 28.8 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 18/49 (36%), Gaps = 4/49 (8%) Query: 209 RLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASI 257 R A +G D+VL E P A + G ++ TG + Sbjct: 55 RAEIALRMGVDVVL----ELPVVFATQDAGGFAFGAVCVLDATGVVTDV 99 >3GG9-A nrPDB Length = 352 Score = 28.8 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 20/46 (43%) Query: 168 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKA 213 G V G + + G G IG + +A G +V ++ ++A Sbjct: 155 GRVLKGQTLGIFGYGKIGQLVAGYGRAFGMNVLVWGRENSKERARA 200 >2JFH-A nrPDB Length = 445 Score = 28.8 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 33/95 (34%), Gaps = 6/95 (6%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAA-QVVVTDLSATRLSKAKEIGADLVLQISKESPQ 230 G V++ G G G+ + A G +V+ T ++ L K E ++ S Sbjct: 5 QGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPE-----AVERHTGSLN 59 Query: 231 EIARKVEGQLGCKPEVTIECTGAEASIQAGIYATR 265 + + P + + A+ AGI Sbjct: 60 DEWLMAADLIVASPGIALAHPSLSAAADAGIEIVG 94 >5M65-A nrPDB Length = 479 Score = 28.8 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 32/78 (41%), Gaps = 4/78 (5%) Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEI 232 G +V G G +G + + G +V+V+++ +A G ++V + E Sbjct: 260 GKVAMVAGFGDVGKGSAASLRQAG-CRVMVSEVDPICALQAAMEGYEVV---TMEDAAPR 315 Query: 233 ARKVEGQLGCKPEVTIEC 250 A G K +TIE Sbjct: 316 ADIFVTATGNKDIITIEH 333 >3FG2-P nrPDB Length = 404 Score = 28.8 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 26/108 (24%), Positives = 36/108 (33%), Gaps = 17/108 (15%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIA 233 V+V GAG IG+ A+A G VV A + A +V + Sbjct: 143 KHVVVIGAGFIGLEFAATARAKGLEVDVV--------ELAPRVMARVVTPEISSYFHDRH 194 Query: 234 RKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGN-----LVLVGLG 276 G + + T A S GN LV+VG+G Sbjct: 195 ----SGAGIRMHYGVRATEIAAEGDRVTGVVLSDGNTLPCDLVVVGVG 238 >2WWR-A nrPDB Length = 330 Score = 28.8 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 16/48 (33%), Gaps = 1/48 (2%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 221 V + G G IG K G + + T A E A+ V Sbjct: 156 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAA-EFQAEFV 202 >3D64-A nrPDB Length = 494 Score = 28.8 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 18/45 (40%), Gaps = 2/45 (4%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATR-LSKAKE 215 G +V G G +G + +GA VT++ L A E Sbjct: 276 AGKIAVVAGYGDVGKGCAQSLRGLGATVW-VTEIDPICALQAAME 319 >3UKH-A nrPDB Length = 519 Score = 28.8 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 15/33 (45%) Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSAT 208 VLV GAGP G+ + ++ D + T Sbjct: 9 VLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNET 41 >2YXL-A nrPDB Length = 450 Score = 28.8 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 42/109 (38%), Gaps = 11/109 (10%) Query: 141 YKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVT--LLVAKAMGAA 198 Y + F EG +I A G V+ A P G T + K G Sbjct: 228 YNFDTSSAFNEGKIIVQEEASAVASIVLDPKPGETVVDLAAAPGGKTTHLAELMKNKG-- 285 Query: 199 QVVVTDLSATRL----SKAKEIGADLV---LQISKESPQEIARKVEGQL 240 ++ D+ R+ K +G +V ++ ++++P+ I +V ++ Sbjct: 286 KIYAFDVDKMRMKRLKDFVKRMGIKIVKPLVKDARKAPEIIGEEVADKV 334 >3M9X-A nrPDB Length = 313 Score = 28.8 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 26/63 (41%) Query: 210 LSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGN 269 + KA+ +GA + +Q + + + ++E + +V + + + + G Sbjct: 25 VKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGI 84 Query: 270 LVL 272 VL Sbjct: 85 KVL 87 >6GAW-AK nrPDB Length = 196 Score = 28.4 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 15/33 (45%) Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSA 207 +V+V G GP + + G + +TD + Sbjct: 150 RVVVKGLGPGRLSAIKGLTMGGLEVISITDNTP 182 >4KUG-A nrPDB Length = 290 Score = 28.4 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 36/90 (40%), Gaps = 15/90 (16%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSK--------AKEIGADLVLQIS 225 KV V GAG +G + A G +V+V D+ + + ++ A + + Sbjct: 2 KKVFVLGAGTMGAGIVQAFAAKG-CEVIVRDIKEEFVDRGIATITKSLSKLVAKEKI--T 58 Query: 226 KESPQEIARKVEGQLGCKP----EVTIECT 251 + +EI ++ G K ++ +E Sbjct: 59 EADKEEILSRISGTTDMKLAADCDLVVEAA 88 >4F86-A nrPDB Length = 320 Score = 28.4 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 23/59 (38%), Gaps = 6/59 (10%) Query: 166 RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSK----AKEIGADL 220 G V G ++ G G G + +A +V LSA + A+E+G D Sbjct: 119 HLGPVGPGDTLVDAGCGRGGSMV--MAHQRFGCKVEGVTLSAAQAEFGNRRARELGIDD 175 >2YQ5-A nrPDB Length = 343 Score = 28.4 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 12/27 (44%) Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVV 201 V + G G IG + AMGA + Sbjct: 150 TVGLIGVGHIGSAVAEIFSAMGAKVIA 176 >3EBC-A nrPDB Length = 317 Score = 28.4 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 17/26 (65%) Query: 47 SDVHYWEYGRIGNFIVKKPMVLGHEA 72 SD+ + +Y + + +K P ++GHEA Sbjct: 52 SDLTFKQYEYLNDLFMKNPAIIGHEA 77 >3E45-A nrPDB Length = 257 Score = 28.4 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 17/26 (65%) Query: 47 SDVHYWEYGRIGNFIVKKPMVLGHEA 72 SD+ + +Y + + +K P ++GHEA Sbjct: 49 SDLTFKQYEYLNDLFMKNPAIIGHEA 74 >2W2L-A nrPDB Length = 348 Score = 28.4 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 50/141 (35%), Gaps = 15/141 (10%) Query: 181 AGPIGMVTLL--VAK----AMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 234 G +G+ + +A+ +G ++V D++ K +GA+ V +S +E+AR Sbjct: 166 LGAVGLGAIQKEIARKAVHGLGM-KLVYYDVAPADAETEKALGAERV-----DSLEELAR 219 Query: 235 KVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDI 294 + + P + + +A A + G +V G ++ L+ A + Sbjct: 220 RSDCVSVSVPYMKLTH---HLIDEAFFAAMKPGSRIVNTARGPVISQDALIAALKSGKLL 276 Query: 295 KGVFRYCNTWPVAISMLASKS 315 P L Sbjct: 277 SAGLDVHEFEPQVSKELIEMK 297 >1QP8-A nrPDB Length = 303 Score = 28.4 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 23/65 (35%), Gaps = 8/65 (12%) Query: 172 LGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQE 231 G KV V G G IG + A+GA QV + G +E+ +E Sbjct: 123 QGEKVAVLGLGEIGTRVGKILAALGA-QVRGFSRTPKE-------GPWRFTNSLEEALRE 174 Query: 232 IARKV 236 V Sbjct: 175 ARAAV 179 >5JE5-A nrPDB Length = 247 Score = 28.4 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 9/20 (45%), Positives = 13/20 (65%) Query: 196 GAAQVVVTDLSATRLSKAKE 215 GAA+VV D+S + A+E Sbjct: 63 GAAKVVGVDISEKMIELARE 82 >1VKF-A nrPDB Length = 188 Score = 28.4 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 31/88 (35%), Gaps = 8/88 (9%) Query: 173 GHKVLV-----CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKE 227 G V V G G G +L K GA ++ + AK+ G VL+ Sbjct: 56 GKTVFVDMDFVNGLGE-GEEAILFVKKAGADGII--TIKPKNYVVAKKNGIPAVLRFFAL 112 Query: 228 SPQEIARKVEGQLGCKPEVTIECTGAEA 255 + + R +E +V GA A Sbjct: 113 DSKAVERGIEQIETLGVDVVEVLPGAVA 140 >1YFM-A nrPDB Length = 488 Score = 28.4 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Query: 50 HYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHL 86 H + GR P+ LG E SG V++V + ++ + Sbjct: 205 HIVKIGRTH-LQDATPLTLGQEFSGYVQQVENGIQRV 240 >3AOE-E nrPDB Length = 419 Score = 28.4 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 6/75 (8%) Query: 150 EEGALIEPLSVGIHACRRGGVTL-GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDL--- 205 ++ A + L V +R G+ L G +V+V G G +G L A+ +G V V Sbjct: 194 DDAAGLGALLVLEALAKRRGLDLRGARVVVQGLGQVGAAVALHAERLGMRVVAVATSMGG 253 Query: 206 --SATRLSKAKEIGA 218 + L A+ + A Sbjct: 254 MYAPEGLDVAEVLSA 268 >3JD5-K nrPDB Length = 197 Score = 28.4 bits (62), Expect = 5.0, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 15/33 (45%) Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSA 207 +V+V G GP + + G + +TD + Sbjct: 151 RVVVKGLGPGRLSAIKGLTMGGLEVISITDNTP 183 >1LTH-T nrPDB Length = 319 Score = 28.4 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 20/39 (51%), Gaps = 1/39 (2%) Query: 175 KVLVCGAGPIGMVTLLVAKAMG-AAQVVVTDLSATRLSK 212 K+ V GAG +G A G A ++V+ D++ R+ Sbjct: 9 KLAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEA 47 >3OC4-A nrPDB Length = 452 Score = 28.4 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 9/16 (56%), Positives = 10/16 (62%) Query: 174 HKVLVCGAGPIGMVTL 189 V V GAGPIGM + Sbjct: 148 QTVAVIGAGPIGMEAI 163 >5GUP-m nrPDB Length = 175 Score = 28.4 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 25/66 (37%), Gaps = 4/66 (6%) Query: 236 VEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIK 295 V G +GC + + G+ + ++ GG LV+ G + M T + + Sbjct: 35 VSGGVGCG--IVLNFGGS--FLGLMVFLIYLGGMLVVFGYTTAMATEMYPEVWVSNKTVF 90 Query: 296 GVFRYC 301 G F Sbjct: 91 GAFVSG 96 >5JFC-L nrPDB Length = 474 Score = 28.4 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 16/30 (53%), Gaps = 2/30 (6%) Query: 173 GHKVLVCGAGPIGMV-TLLVAKAMGAAQVV 201 G KV + GAGP G+ +AK MG + Sbjct: 154 GKKVAIIGAGPAGLTCAADLAK-MGYEVTI 182 >3A26-A nrPDB Length = 301 Score = 28.4 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 19/48 (39%), Gaps = 1/48 (2%) Query: 165 CRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSK 212 R V +++V IG ++L +A G A+V+ + Sbjct: 140 VRMAKVAKPDELVVDMFAGIGHLSLPIA-VYGKAKVIAIEKDPYTFKF 186 >5VJ7-A nrPDB Length = 476 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 16/30 (53%), Gaps = 2/30 (6%) Query: 173 GHKVLVCGAGPIGMV-TLLVAKAMGAAQVV 201 G KV + GAGP G+ +AK MG + Sbjct: 154 GKKVAIIGAGPAGLTCAADLAK-MGYEVTI 182 >4PY5-A nrPDB Length = 271 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 22/54 (40%) Query: 195 MGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248 +G V L + E+G ++S E +E+A ++ K ++ I Sbjct: 87 VGPLVVACIVADEKCLKRLIELGVKDSKKLSNEKVEELASEITETCHGKVKLLI 140 >2EXX-A nrPDB Length = 306 Score = 28.0 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 30/63 (47%), Gaps = 8/63 (12%) Query: 165 CRRGGVTLGHKVLVCGAGPIGMVTLLVAKAM---GAAQVVVTDLSATRLSKAKEI---GA 218 ++ G+ + K++V G G VA+ + G +V V + + AKE+ GA Sbjct: 2 YKKAGLMVDKKLVVV-FGGTGAQGGSVARTLLEDGTFKVRVVTRNPRK-KAAKELRLQGA 59 Query: 219 DLV 221 ++V Sbjct: 60 EVV 62 >4PRK-A nrPDB Length = 336 Score = 28.0 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 12/28 (42%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVV 201 + + G G IG + AMGA + Sbjct: 147 KTIGLIGVGHIGSAVAQIFSAMGAKVLA 174 >5AJ4-AK nrPDB Length = 136 Score = 28.0 bits (61), Expect = 6.1, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 15/33 (45%) Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSA 207 +V+V G GP + + G + +TD + Sbjct: 90 RVVVKGLGPGRLSAIKGLTMGGLEVISITDNTP 122 >5EES-A nrPDB Length = 247 Score = 28.0 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 19/113 (16%), Positives = 35/113 (30%), Gaps = 16/113 (14%) Query: 187 VTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEV 246 V +L AK +V + L EIG D + + EV Sbjct: 4 VGVLGAKGRVGQTIVAAVNESDDLELVAEIGVDD--------------DLSLLVDNGAEV 49 Query: 247 TIECTGAEASIQAGIYATRSGGNLVLVGLGS-EMTTVPLLHAAIREVDIKGVF 298 ++ T ++ + + G +VG + + + + D GV Sbjct: 50 VVDFT-TPNAVMGNLEFCINNGISAVVGTTGFDDARLEQVRDWLEGKDNVGVL 101 >4GBJ-A nrPDB Length = 297 Score = 28.0 bits (61), Expect = 6.5, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 23/51 (45%), Gaps = 1/51 (1%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQI 224 K+ G G +G + G ++VV + +A++ ++GA +V Sbjct: 6 EKIAFLGLGNLGTPIAEILLEAG-YELVVWNRTASKAEPLTKLGATVVENA 55 >5D8N-A nrPDB Length = 529 Score = 28.0 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 27/72 (37%), Gaps = 5/72 (6%) Query: 214 KEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQ----AGIYATRSGGN 269 IGA ++++ + + QL + + +E + GG Sbjct: 47 LAIGATE-NDMARDENSKFKNPLLQQLDSELNGLLSAASSEEDFSGKSGQSVNLRFPGGR 105 Query: 270 LVLVGLGSEMTT 281 + LVGLGS ++ Sbjct: 106 ITLVGLGSSASS 117 >1FOH-A nrPDB Length = 664 Score = 28.0 bits (61), Expect = 7.0, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 18/70 (25%) Query: 176 VLVCGAGPIGMVTL----LVAKAMGAAQVVVTDLSATR-------------LSKAKEIG- 217 VL+ GAGP G++ + +V + D +T+ L K +G Sbjct: 10 VLIVGAGPAGLMAARVLSEYVRQKPDLKVRIIDKRSTKVYNGQADGLQCRTLESLKNLGL 69 Query: 218 ADLVLQISKE 227 AD +L + + Sbjct: 70 ADKILSEAND 79 >3VZS-A nrPDB Length = 257 Score = 28.0 bits (61), Expect = 7.1, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 25/80 (31%), Gaps = 7/80 (8%) Query: 180 GAGPIGMVTLLVAKAMGAAQVVVTDLSATR----LSKAKEIGADLVL---QISKESPQEI 232 G G IG G V ++ R L + K +G D + ++ + Sbjct: 22 GMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVADWDSTKT 81 Query: 233 ARKVEGQLGCKPEVTIECTG 252 A + +V I G Sbjct: 82 AFDKVKSEVGEVDVLINNAG 101 >1DB3-A nrPDB Length = 372 Score = 28.0 bits (61), Expect = 7.1, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 20/53 (37%), Gaps = 1/53 (1%) Query: 39 MHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV-GSSVKHLKPGD 90 + + G+ S + E I + G E G V V G +KPGD Sbjct: 249 VIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAPGVKPGD 301 >3OJO-A nrPDB Length = 431 Score = 27.7 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 21/41 (51%), Gaps = 3/41 (7%) Query: 173 GHKVLVCGAGPIGM-VTLLVAKAMGAAQVVVTDLSATRLSK 212 G K+ V G G IG+ +++ AK V+ D++ + K Sbjct: 11 GSKLTVVGLGYIGLPTSIMFAKH--GVDVLGVDINQQTIDK 49 >1URG-A nrPDB Length = 402 Score = 27.7 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 29/199 (14%), Positives = 51/199 (25%), Gaps = 45/199 (22%) Query: 175 KVLVCGAGP----IGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQ 230 V GP + + AKA G + V+ S Sbjct: 33 TVWSWQTGPELQDVKQIAAQWAKAHGDKVI--------------------VVDQSSNPKG 72 Query: 231 EIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLV--GLGSEMTTVPLLHAA 288 + G P+V G G + V G+ + P Sbjct: 73 FQFYATAARTGKGPDVVF---GMPHDNNG---VFAEEGLMAPVPSGVLNTGLYAP---NT 123 Query: 289 IREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVT----------HRFPLEKALEAFETF 338 I + + G ++ +K + +P T H F ++A F+ Sbjct: 124 IDAIKVNGTMYSVPVSVQVAAIYYNKKLVPQPPQTWAEFVKDANAHGFMYDQANLYFDYA 183 Query: 339 KKGLGLKIMLKCDPSDQNP 357 G + K + +P Sbjct: 184 IIGGYGGYVFKDNNGTLDP 202 >3K8Z-A nrPDB Length = 423 Score = 27.7 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 20/47 (42%) Query: 158 LSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTD 204 + + A +RG G +V+V G G G GA V ++D Sbjct: 205 ICIKEAAKKRGIDIKGARVVVQGFGNAGSYLAKFMHDAGAKVVGISD 251 >4XWI-A nrPDB Length = 262 Score = 27.7 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK-ESPQEIARKVEGQLGCKPEVTIEC 250 A+ A++VVV L+ + GA+ +L ++ S + +V +LG + + Sbjct: 47 ARKSAASRVVVATDDERILAACQGFGAEALLTRAEHNSGTDRLEEVASRLGLASDAIVVN 106 Query: 251 T 251 Sbjct: 107 V 107 >2W6I-D nrPDB Length = 528 Score = 27.7 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 35/205 (17%), Positives = 63/205 (30%), Gaps = 52/205 (25%) Query: 167 RGGVTLGHKVLVCGA--------------------GPIGMVTLLVAKAMGAAQV--VVTD 204 + G T G V V GA G + L VA+ +G + V + D Sbjct: 55 KAGATTGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMD 114 Query: 205 LSAT--RLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEV--------------TI 248 + R K + GA + + + E+ I + + + + + Sbjct: 115 GTEGLVRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFV 174 Query: 249 ECTGAEASIQAGIYAT------RSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVF---- 298 E + + + GI GG + L G TV ++ G + Sbjct: 175 EMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFA 234 Query: 299 ----RYCNTWPVAISMLASKSVNVK 319 R + M+ S +N+K Sbjct: 235 GVGERTREGNDLYHEMIESGVINLK 259 >3RHA-A nrPDB Length = 482 Score = 27.7 bits (60), Expect = 7.7, Method: Composition-based stats. Identities = 8/24 (33%), Positives = 12/24 (50%) Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQ 199 V++ GAGP G+ K G + Sbjct: 10 VVIVGAGPSGLTAARELKKAGLSV 33 >3H9E-O nrPDB Length = 346 Score = 27.7 bits (60), Expect = 7.9, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 40/134 (29%), Gaps = 19/134 (14%) Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTD--LSATRLSKAKEIGADL------------ 220 V + G G IG + L G V V D + + + + Sbjct: 9 TVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDPEYMVYMFKYDSTHGRYKGSVEFRNG 68 Query: 221 --VLQISKESPQEIARKVEGQL-GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGS 277 V+ + S + + +E TG SIQA +G V++ S Sbjct: 69 QLVVDNHEISVYQCKEPKQIPWRAVGSPYVVESTGVYLSIQAASDHISAGAQRVVISAPS 128 Query: 278 EMTTVPLLHAAIRE 291 P+ + E Sbjct: 129 PDA--PMFVMGVNE 140 >4OUR-B nrPDB Length = 544 Score = 27.7 bits (60), Expect = 8.0, Method: Composition-based stats. Identities = 16/112 (14%), Positives = 39/112 (34%), Gaps = 11/112 (9%) Query: 245 EVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKG-----VFR 299 + + GA S + + A L L + D+ G V++ Sbjct: 135 DPALSIAGAVQSQKLAVRAISQ-----LQALPGGDIKLLCDTVVESVRDLTGYDRVMVYK 189 Query: 300 YCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCD 351 + + + SK +++P + +P +A K +++++ C+ Sbjct: 190 FHEDEHGEV-VAESKRDDLEPYIGLHYPATDIPQASRFLFKQNRVRMIVDCN 240 >3TQV-A nrPDB Length = 287 Score = 27.7 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 29/89 (32%), Gaps = 2/89 (2%) Query: 181 AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQEIARKVEG 238 AG I K V V + L++A AD+V+ S E G Sbjct: 182 AGGIAKAVTKAKKLDSNKVVEVEVTNLDELNQAIAAKADIVMLDNFSGEDIDIAVSIARG 241 Query: 239 QLGCKPEVTIECTGAEASIQAGIYATRSG 267 ++ + I+ A + G+ G Sbjct: 242 KVALEVSGNIDRNSIVAIAKTGVDFISVG 270 >4X4J-A nrPDB Length = 507 Score = 27.7 bits (60), Expect = 8.7, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 22/44 (50%), Gaps = 1/44 (2%) Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGAD 219 V++ GAGP G++ + G VVV + R +++ +G Sbjct: 25 VVIAGAGPAGLMLAGELRLAGIG-VVVLERLPARTGESRGLGFT 67 >1VLM-A nrPDB Length = 219 Score = 27.7 bits (60), Expect = 8.7, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 34/100 (34%), Gaps = 14/100 (14%) Query: 259 AGIYATRSGGNLVLVGLGSEMTTVPLLHAAIRE--------VDIKGVFRYCNTWPVAISM 310 + G V +G+G+ VPL E +GVF T Sbjct: 40 QAVKCLLPEGRGVEIGVGTGRFAVPLKIKIGVEPSERMAEIARKRGVFVLKGTAENLP-- 97 Query: 311 LASKSVNVKPLVTHRFPLEK----ALEAFETFKKGLGLKI 346 L +S + +VT ++ EA+ KKG L + Sbjct: 98 LKDESFDFALMVTTICFVDDPERALKEAYRILKKGGYLIV 137 >1EUZ-A nrPDB Length = 419 Score = 27.7 bits (60), Expect = 9.0, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 17/35 (48%), Gaps = 1/35 (2%) Query: 173 GHKVLVCGAGPIGMVTLLVAK-AMGAAQVVVTDLS 206 G K+ V G G G T +AK +G V V+D Sbjct: 212 GKKIAVQGYGNAGYYTAKLAKEQLGMTVVAVSDSR 246 >5B1I-A nrPDB Length = 311 Score = 27.3 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 30/76 (39%), Gaps = 2/76 (2%) Query: 164 ACRRGGVTLGHKVL--VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 221 +RG V ++ G IG+ A + VV S + + +GA++V Sbjct: 53 GLQRGRVNAKTTIIEPTAGNTGIGLALATQAHHLRTILVVPEKFSMEKQVLMQALGAEIV 112 Query: 222 LQISKESPQEIARKVE 237 S+E + RK E Sbjct: 113 HTPSEEGIKGAIRKAE 128 >4P4L-A nrPDB Length = 277 Score = 27.3 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 19/41 (46%) Query: 177 LVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIG 217 LV G+G ++ +G + V ++ + ++ ++G Sbjct: 121 LVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLG 161 >5J46-A nrPDB Length = 189 Score = 27.3 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 12/30 (40%), Gaps = 3/30 (10%) Query: 183 PIGMVTLLVAKAMGAAQVVVTDLSATRLSK 212 IG+ V +V+V D+S + Sbjct: 66 GIGLAATQVDVH---ERVIVIDVSEDKNEL 92 >2G5C-A nrPDB Length = 281 Score = 27.3 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 21/45 (46%), Gaps = 1/45 (2%) Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAA-QVVVTDLSATRLSKAKEIG 217 VL+ G G +G + G ++ D++ +SKA ++G Sbjct: 2 QNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLG 46 >2B4Q-A nrPDB Length = 276 Score = 27.3 bits (59), Expect = 10.0, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 28/88 (31%), Gaps = 6/88 (6%) Query: 172 LGHKVLVCGAG-PIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGA-----DLVLQIS 225 G LV G IG + GA + + A + A + +S Sbjct: 28 AGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPADLS 87 Query: 226 KESPQEIARKVEGQLGCKPEVTIECTGA 253 E+ + G+L + ++ + G Sbjct: 88 SEAGARRLAQALGELSARLDILVNNAGT 115 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.140 0.369 Lambda K H 0.267 0.0426 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,703,913 Number of Sequences: 36641 Number of extensions: 579853 Number of successful extensions: 3823 Number of sequences better than 10.0: 414 Number of HSP's better than 10.0 without gapping: 324 Number of HSP's successfully gapped in prelim test: 207 Number of HSP's that attempted gapping in prelim test: 2756 Number of HSP's gapped (non-prelim): 599 length of query: 357 length of database: 10,336,785 effective HSP length: 98 effective length of query: 259 effective length of database: 6,745,967 effective search space: 1747205453 effective search space used: 1747205453 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)