BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q00539 (523 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5ZWN-V nrPDB 1067 0.0 6R5K-D nrPDB 67 2e-11 2DH7-A nrPDB 64 2e-10 6AH0-4 nrPDB 63 4e-10 3SXL-A nrPDB 58 8e-09 6QX9-R nrPDB 58 9e-09 6ID0-O nrPDB 56 5e-08 6QDV-M nrPDB 55 5e-08 5ZWM-4 nrPDB 54 2e-07 2XS5-A nrPDB 52 6e-07 2XS2-A nrPDB 51 2e-06 2YTC-A nrPDB 50 2e-06 5MDU-A nrPDB 48 9e-06 4EGL-A nrPDB 48 1e-05 1P1T-A nrPDB 48 1e-05 3NNA-A nrPDB 47 2e-05 3HI9-A nrPDB 47 2e-05 5SZW-A nrPDB 47 2e-05 4FXV-A nrPDB 47 3e-05 2YWK-A nrPDB 46 3e-05 5ZWN-Q nrPDB 46 4e-05 6G90-B nrPDB 46 4e-05 1FNX-H nrPDB 46 4e-05 1FXL-A nrPDB 45 7e-05 2RT3-A nrPDB 45 9e-05 1D8Z-A nrPDB 45 1e-04 2CJK-A nrPDB 44 1e-04 6FF4-1 nrPDB 44 1e-04 6GD1-A nrPDB 44 2e-04 6D0Y-A nrPDB 44 2e-04 5ZWM-X nrPDB 43 3e-04 4LMZ-A nrPDB 42 5e-04 1SXL-A nrPDB 42 6e-04 5MMM-v nrPDB 42 0.001 2SXL-A nrPDB 41 0.001 2MYF-A nrPDB 40 0.003 4PKD-B nrPDB 39 0.006 2KN4-A nrPDB 39 0.006 2LEC-A nrPDB 39 0.007 1D9A-A nrPDB 39 0.007 6QX9-1A nrPDB 38 0.008 6ASO-A nrPDB 38 0.009 1X5P-A nrPDB 37 0.018 2CPE-A nrPDB 37 0.020 5OO6-B nrPDB 37 0.021 6GML-X nrPDB 37 0.021 3CW1-K nrPDB 37 0.023 1H6K-X nrPDB 37 0.027 6QX9-1K nrPDB 36 0.033 2DH8-A nrPDB 36 0.034 5EV3-A nrPDB 36 0.038 2BZ2-A nrPDB 36 0.039 5EN1-A nrPDB 36 0.039 5MQF-o nrPDB 36 0.040 2RS2-A nrPDB 36 0.045 1UAW-A nrPDB 36 0.047 2CQB-A nrPDB 35 0.061 6C8U-1 nrPDB 35 0.11 6AH0-p nrPDB 35 0.11 6EM1-o nrPDB 34 0.12 5X3Y-A nrPDB 34 0.12 2MST-A nrPDB 34 0.12 3MDF-A nrPDB 34 0.13 2KU7-A nrPDB 34 0.13 2CQ3-A nrPDB 34 0.13 2DH9-A nrPDB 34 0.14 1X4A-A nrPDB 34 0.17 2ERR-A nrPDB 33 0.23 3N9U-C nrPDB 33 0.24 2DGS-A nrPDB 33 0.29 1RK8-A nrPDB 33 0.37 1OO0-B nrPDB 33 0.37 2MGZ-B nrPDB 33 0.41 5YVG-X nrPDB 33 0.42 4ZKA-A nrPDB 32 0.50 5LJ5-M nrPDB 32 0.60 2EVZ-A nrPDB 32 0.63 1QM9-A nrPDB 32 0.78 6D6V-H nrPDB 32 0.84 2CQH-A nrPDB 32 0.95 2DGP-A nrPDB 31 1.1 2MKI-A nrPDB 31 1.2 3U1M-A nrPDB 31 1.4 2RUG-A nrPDB 31 1.4 5YZG-w nrPDB 30 2.2 3EX7-B nrPDB 30 2.2 2J0Q-D nrPDB 30 2.2 2HYI-B nrPDB 30 2.2 1P27-B nrPDB 30 2.2 3NNH-A nrPDB 30 2.5 1L6J-A nrPDB 30 3.4 2I2Y-A nrPDB 29 4.0 4WKR-A nrPDB 29 4.6 4F19-A nrPDB 28 9.7 >5ZWN-V nrPDB Length = 523 Score = 1067 bits (2760), Expect = 0.0, Method: Compositional matrix adjust. Identities = 523/523 (100%), Positives = 523/523 (100%) Query: 1 MSYKQTTYYPSRGNLVRNDSSPYTNTISSETNNSSTSVLSLQGASNVSLGTTGNQLYMGD 60 MSYKQTTYYPSRGNLVRNDSSPYTNTISSETNNSSTSVLSLQGASNVSLGTTGNQLYMGD Sbjct: 1 MSYKQTTYYPSRGNLVRNDSSPYTNTISSETNNSSTSVLSLQGASNVSLGTTGNQLYMGD 60 Query: 61 LDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAA 120 LDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAA Sbjct: 61 LDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAA 120 Query: 121 NALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLF 180 NALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLF Sbjct: 121 NALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLF 180 Query: 181 ELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPT 240 ELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPT Sbjct: 181 ELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPT 240 Query: 241 SGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQ 300 SGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQ Sbjct: 241 SGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQ 300 Query: 301 QPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLS 360 QPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLS Sbjct: 301 QPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLS 360 Query: 361 AEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYIPS 420 AEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYIPS Sbjct: 361 AEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYIPS 420 Query: 421 STCEAPVLPDNNVSSTMLPGCQILNYSNPYANANGLGSNNFSFYSNNNATNTQATSLLAD 480 STCEAPVLPDNNVSSTMLPGCQILNYSNPYANANGLGSNNFSFYSNNNATNTQATSLLAD Sbjct: 421 STCEAPVLPDNNVSSTMLPGCQILNYSNPYANANGLGSNNFSFYSNNNATNTQATSLLAD 480 Query: 481 TSSMDLSGTGGQQVIMQGSEAVVNSTNAMLNRLEQGSNGFMFA 523 TSSMDLSGTGGQQVIMQGSEAVVNSTNAMLNRLEQGSNGFMFA Sbjct: 481 TSSMDLSGTGGQQVIMQGSEAVVNSTNAMLNRLEQGSNGFMFA 523 >6R5K-D nrPDB Length = 581 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 90/421 (21%), Positives = 163/421 (38%), Gaps = 84/421 (19%) Query: 43 GASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGP 102 G+ + S+ + LY+GDL+P+ + + I++ +G + ++R+ + Sbjct: 31 GSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVS-SIRVCRDAIT---------- 79 Query: 103 KNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNN 162 K + GY +V+F + H A + + ++ W S + SL SGN Sbjct: 80 KTSLGYAYVNF--NDHEAGRKAIEQLNYTPIKGRLCRIMW-----SQRDPSLRKKGSGN- 131 Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 IF+ +L P++ L++ F + + +KI D+ G SKG+GFV F + A+ Sbjct: 132 --IFIKNLHPDIDNKALYDTF-SVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAI 187 Query: 223 SEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSL-----NNENVDSRFLS------ 271 + G+ LNG+ I V P +++ S + ++L N+E D +F Sbjct: 188 DALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFG 247 Query: 272 ---------------KGQSFLS-------------------NGNN---NMGFKRNHMSQF 294 KG F++ NG K+N Sbjct: 248 PIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHV 307 Query: 295 IYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI-----PVGKC 349 + + L +F+ L V +++L F P+GTI K+ K Sbjct: 308 LKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKG 367 Query: 350 CGFVQYVDRLSAEAAIAG-----MQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQ 404 GFV + A AI + G P+ V ++ + +++ L QQ N ++ Q Sbjct: 368 FGFVCFSTPEEATKAITEKNQQIVAGKPLY---VAIAQRKDVRRSQLAQQIQARNQMRYQ 424 Query: 405 Q 405 Q Sbjct: 425 Q 425 >2DH7-A nrPDB Length = 105 Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 35/93 (37%), Positives = 49/93 (52%), Gaps = 12/93 (12%) Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 N+ +FVGDL+P +T + F + S A++V D TG SKGYGFV F N + + Sbjct: 14 NHFHVFVGDLSPEITTEDIKSAFAP-FGKISDARVVKDMATGKSKGYGFVSFYNKLDAEN 72 Query: 221 ALSEMQGVFLNGRAIKV-----------GPTSG 242 A+ M G +L GR I+ GP+SG Sbjct: 73 AIVHMGGQWLGGRQIRTNWATRKPPAPSGPSSG 105 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 12/90 (13%) Query: 299 QQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTI----VYVKIPVGKC--CGF 352 Q++ + NHF VF+G LS +T +++++ F PFG I V + GK GF Sbjct: 8 QKKDTSNHFH------VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGF 61 Query: 353 VQYVDRLSAEAAIAGMQGFPIANSRVRLSW 382 V + ++L AE AI M G + ++R +W Sbjct: 62 VSFYNKLDAENAIVHMGGQWLGGRQIRTNW 91 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 21/90 (23%), Positives = 41/90 (45%), Gaps = 13/90 (14%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFP 114 +++GDL P ++ +A G+ + + R++ M ++GY FV F Sbjct: 17 HVFVGDLSPEITTEDIKSAFAPFGKIS-DARVV----------KDMATGKSKGYGFVSFY 65 Query: 115 SSTHAANALLKNGMLIPNFPNKKLKLNWAT 144 + A NA++ G ++++ NWAT Sbjct: 66 NKLDAENAIVHMGGQW--LGGRQIRTNWAT 93 >6AH0-4 nrPDB Length = 424 Score = 62.8 bits (151), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 49/181 (27%), Positives = 81/181 (44%), Gaps = 17/181 (9%) Query: 63 PTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSR-SSMGPKN-----NQGYCFVDFPSS 116 P ++N ++ + ++ ++W L G ++ PK+ +QGY FV+F S Sbjct: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64 Query: 117 THAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTE 176 A A+ M+ K +++N A++ N + N IF+G+L P + E Sbjct: 65 EDADYAIKIMNMI--KLYGKPIRVNKASAHNKNLDVGAN---------IFIGNLDPEIDE 113 Query: 177 SQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIK 236 L++ F KI+ D TG SKGY F+ F + D A+ M G +L R I Sbjct: 114 KLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPIT 173 Query: 237 V 237 V Sbjct: 174 V 174 Score = 33.1 bits (74), Expect = 0.32, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 34/75 (45%), Gaps = 6/75 (8%) Query: 312 NTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCC------GFVQYVDRLSAEAAI 365 + TV++GGL V+E L F G +V +P + GFV+++ A+ AI Sbjct: 12 DATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAI 71 Query: 366 AGMQGFPIANSRVRL 380 M + +R+ Sbjct: 72 KIMNMIKLYGKPIRV 86 >3SXL-A nrPDB Length = 184 Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 37/127 (29%), Positives = 65/127 (51%), Gaps = 15/127 (11%) Query: 107 GYCFVDFPSSTHAANAL-LKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSI 165 GY FVDF S + A+ + NG+ + N K+LK+++A +S + ++ Sbjct: 57 GYAFVDFTSEMDSQRAIKVLNGITVRN---KRLKVSYARPG----------GESIKDTNL 103 Query: 166 FVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEM 225 +V +L +T+ QL +F +Y S I+ D++TG +G FV++ +E Q A+S + Sbjct: 104 YVTNLPRTITDDQLDTIF-GKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISAL 162 Query: 226 QGVFLNG 232 V G Sbjct: 163 NNVIPEG 169 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Query: 150 SNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGF 209 ++ L N +N ++ V L ++T+ +L+ LF + +I+ D TG S GY F Sbjct: 2 ESDDLMNDPRASNTNLIVNYLPQDMTDRELYALF-RAIGPINTCRIMRDYKTGYSFGYAF 60 Query: 210 VKFTNSDEQQLALSEMQGVFLNGRAIKV 237 V FT+ + Q A+ + G+ + + +KV Sbjct: 61 VDFTSEMDSQRAIKVLNGITVRNKRLKV 88 Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 6/63 (9%) Query: 312 NTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCG------FVQYVDRLSAEAAI 365 +T +++ L +T+D+L F +G+IV I K G FV+Y R A+ AI Sbjct: 100 DTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAI 159 Query: 366 AGM 368 + + Sbjct: 160 SAL 162 >6QX9-R nrPDB Length = 480 Score = 58.2 bits (139), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 1/77 (1%) Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 ++ IF GDL V + L F +R+ S AK++ D+ TG +KGYGFV F + + Sbjct: 379 DDFRIFCGDLGNEVNDDILARAF-SRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVR 437 Query: 221 ALSEMQGVFLNGRAIKV 237 A+ EM G ++ R IK+ Sbjct: 438 AMREMNGKYVGSRPIKL 454 >6ID0-O nrPDB Length = 420 Score = 55.8 bits (133), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Query: 302 PSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSA 361 P L+ D TT+++GGL +TE +LR +F FG I + + + C F+Q+ R +A Sbjct: 221 PRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAA 280 Query: 362 E-AAIAGMQGFPIANSRVRLSWGRS 385 E AA + R+ + WGRS Sbjct: 281 EVAAEKSFNKLIVNGRRLNVKWGRS 305 >6QDV-M nrPDB Length = 289 Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Query: 302 PSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSA 361 P L+ D TT+++GGL +TE +LR +F FG I + + + C F+Q+ R +A Sbjct: 204 PRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAA 263 Query: 362 E-AAIAGMQGFPIANSRVRLSWGRS 385 E AA + R+ + WGRS Sbjct: 264 EVAAEKSFNKLIVNGRRLNVKWGRS 288 >5ZWM-4 nrPDB Length = 213 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 55/231 (23%), Positives = 90/231 (38%), Gaps = 60/231 (25%) Query: 159 SGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQ 218 SGN +++VG++ P +T+ QL+ELFI + K D+V +GY F++F N + Sbjct: 7 SGN--TVYVGNIDPRITKEQLYELFI-QINPVLRIKYPKDKVLQAYQGYAFIEFYNQGDA 63 Query: 219 QLALSEMQG-VFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFL 277 Q A+ M V L R IKV + Sbjct: 64 QYAIKIMNNTVRLYDRLIKVRQVTN----------------------------------- 88 Query: 278 SNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFG 337 S G N+ N I P+ + +FI L+ + D+L F FG Sbjct: 89 STGTTNLP--SNISKDMILPIAK--------------LFIKNLADSIDSDQLVKIFNKFG 132 Query: 338 TIV----YVKIPVGKC-CGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWG 383 ++ + GK C +V + D A+ AI + +AN+R+ + + Sbjct: 133 KLIREPEIFYLSNGKLKCAYVYFEDFEKADLAIKSLNNQLVANNRITVDYA 183 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 40/187 (21%), Positives = 82/187 (43%), Gaps = 34/187 (18%) Query: 50 GTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNN---- 105 +GN +Y+G++DP K Q++ + N +R+ + PK+ Sbjct: 5 ADSGNTVYVGNIDPRITK---EQLYELFIQINPVLRIKY-------------PKDKVLQA 48 Query: 106 -QGYCFVDFPSSTHAANAL-LKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSG--N 161 QGY F++F + A A+ + N + ++ +K+ T+S +N N K Sbjct: 49 YQGYAFIEFYNQGDAQYAIKIMNNTV--RLYDRLIKVRQVTNSTGTTNLPSNISKDMILP 106 Query: 162 NCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGY---GFVKFTNSDEQ 218 +F+ +LA ++ QL ++F N++ I ++ +S G +V F + ++ Sbjct: 107 IAKLFIKNLADSIDSDQLVKIF-NKFGKL----IREPEIFYLSNGKLKCAYVYFEDFEKA 161 Query: 219 QLALSEM 225 LA+ + Sbjct: 162 DLAIKSL 168 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 14/90 (15%) Query: 304 LNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCC------GFVQYVD 357 +N+ D NT V++G + +T+++L F ++ +K P K F+++ + Sbjct: 1 MNYSADSGNT-VYVGNIDPRITKEQLYELFIQINPVLRIKYPKDKVLQAYQGYAFIEFYN 59 Query: 358 RLSAEAAIAGMQGFPIANSRVRLSWGRSAK 387 + A+ AI I N+ VRL + R K Sbjct: 60 QGDAQYAI------KIMNNTVRL-YDRLIK 82 >2XS5-A nrPDB Length = 87 Score = 52.0 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 30/82 (36%), Positives = 49/82 (59%), Gaps = 6/82 (7%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNS-DEQQLAL 222 ++FVG + + E+++ F RY S KI+ D+ TG+SKGYGFV F N D Q++ Sbjct: 11 TVFVGGIDVRMDETEIRSFFA-RYGSVKEVKIITDR-TGVSKGYGFVSFYNDVDVQKIVE 68 Query: 223 SEMQGVFLNGRAIKVGPTSGQQ 244 S++ +G+ +K+GP +Q Sbjct: 69 SQIN---FHGKKLKLGPAIRKQ 87 Score = 36.6 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 7/67 (10%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI-----PVGKCCGFVQYVDRLSAEAA 364 PN TVF+GG+ + E E+R++F +G++ VKI V K GFV + + + + Sbjct: 9 PN--TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKI 66 Query: 365 IAGMQGF 371 + F Sbjct: 67 VESQINF 73 >2XS2-A nrPDB Length = 102 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 30/82 (36%), Positives = 49/82 (59%), Gaps = 6/82 (7%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNS-DEQQLAL 222 ++FVG + + E+++ F RY S KI+ D+ TG+SKGYGFV F N D Q++ Sbjct: 11 TVFVGGIDVRMDETEIRSFFA-RYGSVKEVKIITDR-TGVSKGYGFVSFYNDVDVQKIVE 68 Query: 223 SEMQGVFLNGRAIKVGPTSGQQ 244 S++ +G+ +K+GP +Q Sbjct: 69 SQIN---FHGKKLKLGPAIRKQ 87 Score = 35.8 bits (81), Expect = 0.048, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 7/67 (10%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI-----PVGKCCGFVQYVDRLSAEAA 364 PN TVF+GG+ + E E+R++F +G++ VKI V K GFV + + + + Sbjct: 9 PN--TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKI 66 Query: 365 IAGMQGF 371 + F Sbjct: 67 VESQINF 73 >2YTC-A nrPDB Length = 85 Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Query: 309 DPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAE-AAIAG 367 D TT+++GGL +TE +LR +F FG I + + + C F+Q+ R +AE AA Sbjct: 9 DKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEVAAEKS 68 Query: 368 MQGFPIANSRVRLSWGR 384 + R+ + WGR Sbjct: 69 FNKLIVNGRRLNVKWGR 85 >5MDU-A nrPDB Length = 157 Score = 48.1 bits (113), Expect = 9e-06, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 40/70 (57%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPI 373 T+F+GG++ V E LR+ F+ FG++ + + GF++ R +AE A M+ P Sbjct: 24 TLFLGGITRSVREPVLRSMFERFGSVQSLILNHNYRHGFLKMFRRDAAEKAQVAMENVPF 83 Query: 374 ANSRVRLSWG 383 A++ +R WG Sbjct: 84 ADTTIRTKWG 93 >4EGL-A nrPDB Length = 177 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 31/109 (28%), Positives = 55/109 (50%), Gaps = 5/109 (4%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 + V L N+T+ +L LF + AK++ D+V G S GYGFV + + + + A++ Sbjct: 5 LIVNYLPQNMTQDELRSLF-SSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 63 Query: 225 MQGVFLNGRAIKVGPTSGQQQHVSGNNDY----NRSSSSLNNENVDSRF 269 + G+ L + IKV + + N Y R+ + + E++ SRF Sbjct: 64 LNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 112 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 33/162 (20%), Positives = 81/162 (50%), Gaps = 26/162 (16%) Query: 67 KNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAANAL-LK 125 ++ +R +++S+GE + +++ + + + GY FV++ ++ A A+ Sbjct: 16 QDELRSLFSSIGEVE-SAKLIRDKVAGH----------SLGYGFVNYVTAKDAERAINTL 64 Query: 126 NGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFIN 185 NG+ +K +K+++A S +K N +++ L +T+ + ++F + Sbjct: 65 NGL---RLQSKTIKVSYARPSS-------EVIKDAN---LYISGLPRTMTQKDVEDMF-S 110 Query: 186 RYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQG 227 R+ +++++ DQ TG+S+G F++F E + A++ G Sbjct: 111 RFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 152 Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 6/72 (8%) Query: 324 VTEDELRAYFQPFGTIVYVKIPVGKCCG------FVQYVDRLSAEAAIAGMQGFPIANSR 377 +T+DELR+ F G + K+ K G FV YV AE AI + G + + Sbjct: 14 MTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKT 73 Query: 378 VRLSWGRSAKQT 389 +++S+ R + + Sbjct: 74 IKVSYARPSSEV 85 >1P1T-A nrPDB Length = 104 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 24/81 (29%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 S+FVG++ TE QL ++F + ++V+D+ TG KGYGF ++ + + A+ Sbjct: 10 SVFVGNIPYEATEEQLKDIF-SEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMR 68 Query: 224 EMQGVFLNGRAIKVGPTSGQQ 244 + G +GRA++V + ++ Sbjct: 69 NLNGREFSGRALRVDNAASEK 89 Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 6/86 (6%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAEAAIAG 367 +VF+G + TE++L+ F G +V ++ K GF +Y D+ +A +A+ Sbjct: 10 SVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRN 69 Query: 368 MQGFPIANSRVRLSWGRSAKQTALLQ 393 + G + +R+ S K L+ Sbjct: 70 LNGREFSGRALRVDNAASEKNKEELK 95 >3NNA-A nrPDB Length = 175 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 42/175 (24%), Positives = 81/175 (46%), Gaps = 25/175 (14%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEA-NINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 ++++G + TW + +R+++ G INV L + S++ P ++G CFV F Sbjct: 5 KMFVGQVPRTWSEKDLRELFEQYGAVYEINV-------LRDRSQN---PPQSKGCCFVTF 54 Query: 114 PSSTHAANA--LLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLA 171 + A A L N ++P + +++ A S NN++ + K +F+G ++ Sbjct: 55 YTRKAALEAQNALHNMKVLPGM-HHPIQMKPADS---EKNNAVEDRK------LFIGMIS 104 Query: 172 PNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQ 226 TE+ + +F + + +I+ G+S+G FV FT Q A+ M Sbjct: 105 KKCTENDIRVMF-SSFGQIEECRILRGP-DGLSRGCAFVTFTTRAMAQTAIKAMH 157 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 12/83 (14%) Query: 296 YPVQQQPSLNHFTDPNNTT----VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG---- 347 +P+Q +P+ ++ NN +FIG +S TE+++R F FG I +I G Sbjct: 78 HPIQMKPAD---SEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGL 134 Query: 348 -KCCGFVQYVDRLSAEAAIAGMQ 369 + C FV + R A+ AI M Sbjct: 135 SRGCAFVTFTTRAMAQTAIKAMH 157 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 11/88 (12%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKI--------PVGKCCGFVQYVDR---LSAEA 363 +F+G + +E +LR F+ +G + + + P K C FV + R L A+ Sbjct: 6 MFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 65 Query: 364 AIAGMQGFPIANSRVRLSWGRSAKQTAL 391 A+ M+ P + +++ S K A+ Sbjct: 66 ALHNMKVLPGMHHPIQMKPADSEKNNAV 93 >3HI9-A nrPDB Length = 84 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 + V L N+T+ +L LF + AK++ D+V G S GYGFV + + + + A++ Sbjct: 7 LIVNYLPQNMTQDELRSLF-SSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 65 Query: 225 MQGVFLNGRAIKV 237 + G+ L + IKV Sbjct: 66 LNGLRLQSKTIKV 78 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 6/81 (7%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCC------GFVQYVDRLSAEA 363 P T + + L +T+DELR+ F G + K+ K GFV YV AE Sbjct: 2 PGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 61 Query: 364 AIAGMQGFPIANSRVRLSWGR 384 AI + G + + +++S+ R Sbjct: 62 AINTLNGLRLQSKTIKVSYAR 82 >5SZW-A nrPDB Length = 101 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 + V L N+T+ +L LF + AK++ D+V G S GYGFV + + + + A++ Sbjct: 24 LIVNYLPQNMTQDELRSLF-SSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 82 Query: 225 MQGVFLNGRAIKV 237 + G+ L + IKV Sbjct: 83 LNGLRLQSKTIKV 95 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 6/82 (7%) Query: 309 DPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCG------FVQYVDRLSAE 362 D T + + L +T+DELR+ F G + K+ K G FV YV AE Sbjct: 18 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 77 Query: 363 AAIAGMQGFPIANSRVRLSWGR 384 AI + G + + +++S+ R Sbjct: 78 RAINTLNGLRLQSKTIKVSYAR 99 >4FXV-A nrPDB Length = 99 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 + V L N+T+ +L LF + AK++ D+V G S GYGFV + + + + A++ Sbjct: 22 LIVNYLPQNMTQDELRSLF-SSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80 Query: 225 MQGVFLNGRAIKV 237 + G+ L + IKV Sbjct: 81 LNGLRLQSKTIKV 93 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 6/67 (8%) Query: 324 VTEDELRAYFQPFGTIVYVKIPVGKCCG------FVQYVDRLSAEAAIAGMQGFPIANSR 377 +T+DELR+ F G + K+ K G FV YV AE AI + G + + Sbjct: 31 MTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKT 90 Query: 378 VRLSWGR 384 +++S+ R Sbjct: 91 IKVSYAR 97 >2YWK-A nrPDB Length = 95 Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 29/80 (36%), Positives = 45/80 (56%), Gaps = 3/80 (3%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++FVG+L V E L+ELF+ + + I D+ G K +GFV F + + A++ Sbjct: 18 TVFVGNLEARVREEILYELFL-QAGPLTKVTICKDR-EGKPKSFGFVCFKHPESVSYAIA 75 Query: 224 EMQGVFLNGRAIKV-GPTSG 242 + G+ L GR I V GP+SG Sbjct: 76 LLNGIRLYGRPINVSGPSSG 95 >5ZWN-Q nrPDB Length = 300 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 4/83 (4%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 +IF+G L ++ E +L + F+ ++ +IV D++T SKGY F+ F + ++A Sbjct: 108 TIFIGRLPYDLDEIELQKYFV-KFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFK 166 Query: 224 EM---QGVFLNGRAIKVGPTSGQ 243 E+ +G+ + R V G+ Sbjct: 167 EIGVHRGIQIKDRICIVDIERGR 189 Score = 36.2 bits (82), Expect = 0.040, Method: Compositional matrix adjust. Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 12/91 (13%) Query: 308 TDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCC------GFVQYVDRLSA 361 TDP T +FIG L + E EL+ YF FG I ++I K F+ + D +S+ Sbjct: 103 TDPYRT-IFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISS 161 Query: 362 EAA---IAGMQGFPIANS--RVRLSWGRSAK 387 + A I +G I + V + GR+ K Sbjct: 162 KMAFKEIGVHRGIQIKDRICIVDIERGRTVK 192 >6G90-B nrPDB Length = 300 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 4/83 (4%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 +IF+G L ++ E +L + F+ ++ +IV D++T SKGY F+ F + ++A Sbjct: 108 TIFIGRLPYDLDEIELQKYFV-KFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFK 166 Query: 224 EM---QGVFLNGRAIKVGPTSGQ 243 E+ +G+ + R V G+ Sbjct: 167 EIGVHRGIQIKDRICIVDIERGR 189 Score = 35.4 bits (80), Expect = 0.054, Method: Compositional matrix adjust. Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 12/91 (13%) Query: 308 TDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCC------GFVQYVDRLSA 361 TDP T +FIG L + E EL+ YF FG I ++I K F+ + D +S+ Sbjct: 103 TDPYRT-IFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISS 161 Query: 362 EAA---IAGMQGFPIANS--RVRLSWGRSAK 387 + A I +G I + V + GR+ K Sbjct: 162 KMAFKEIGVHRGIQIKDRICIVDIERGRTVK 192 >1FNX-H nrPDB Length = 174 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 15/122 (12%) Query: 107 GYCFVDFPSSTHAANAL-LKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSI 165 GY FV++ A A+ NG+ K +K+++A S + S + ++ Sbjct: 47 GYGFVNYSDPNDADKAINTLNGL---KLQTKTIKVSYARPSSA----------SIRDANL 93 Query: 166 FVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEM 225 +V L +++ ++ +LF ++Y ++I+ DQ TG+S+G GF++F E + A+ + Sbjct: 94 YVSGLPKTMSQKEMEQLF-SQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGL 152 Query: 226 QG 227 G Sbjct: 153 NG 154 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 + V L N+T+ + LF K+V D++TG S GYGFV +++ ++ A++ Sbjct: 7 LIVNYLPQNMTQDEFKSLF-GSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 65 Query: 225 MQGVFLNGRAIKV 237 + G+ L + IKV Sbjct: 66 LNGLKLQTKTIKV 78 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 6/79 (7%) Query: 312 NTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCG------FVQYVDRLSAEAAI 365 T + + L +T+DE ++ F G I K+ K G FV Y D A+ AI Sbjct: 4 KTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAI 63 Query: 366 AGMQGFPIANSRVRLSWGR 384 + G + +++S+ R Sbjct: 64 NTLNGLKLQTKTIKVSYAR 82 >1FXL-A nrPDB Length = 167 Score = 45.1 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 34/122 (27%), Positives = 63/122 (51%), Gaps = 15/122 (12%) Query: 107 GYCFVDFPSSTHAANAL-LKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSI 165 GY FV++ A A+ NG+ K +K+++A S + S + ++ Sbjct: 45 GYGFVNYIDPKDAEKAINTLNGL---RLQTKTIKVSYARPSSA----------SIRDANL 91 Query: 166 FVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEM 225 +V L +T+ +L +LF ++Y ++I+ DQVTG+S+G GF++F E + A+ + Sbjct: 92 YVSGLPKTMTQKELEQLF-SQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 150 Query: 226 QG 227 G Sbjct: 151 NG 152 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 1/74 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++ V L N+T+ + LF K+V D++TG S GYGFV + + + + A++ Sbjct: 4 NLIVNYLPQNMTQEEFRSLF-GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 62 Query: 224 EMQGVFLNGRAIKV 237 + G+ L + IKV Sbjct: 63 TLNGLRLQTKTIKV 76 Score = 35.8 bits (81), Expect = 0.045, Method: Composition-based stats. Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 11/120 (9%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCG------FVQYVDRLSAEAA 364 + T + + L +T++E R+ F G I K+ K G FV Y+D AE A Sbjct: 1 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 60 Query: 365 IAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNS-LQVQQQQPGLQQ--PNYGYIPSS 421 I + G + +++S+ R + +A ++ A L S L Q L+Q YG I +S Sbjct: 61 INTLNGLRLQTKTIKVSYARPS--SASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS 118 >2RT3-A nrPDB Length = 97 Score = 44.7 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 27/72 (37%), Positives = 41/72 (56%), Gaps = 5/72 (6%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIA 374 VF+G L + +TEDE+R +PFG I +KI + FV + L+ AAI +Q P+ Sbjct: 21 VFLGNLPNGITEDEIREDLEPFGPIDQIKIVTERNIAFVHF---LNIAAAIKAVQELPLN 77 Query: 375 N--SRVRLSWGR 384 S+ R+ +GR Sbjct: 78 PKWSKRRIYYGR 89 >1D8Z-A nrPDB Length = 89 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 + V L N+T+ + LF K+V D++TG S GYGFV +++ ++ A++ Sbjct: 7 LIVNYLPQNMTQDEFKSLF-GSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 65 Query: 225 MQGVFLNGRAIKV 237 + G+ L + IKV Sbjct: 66 LNGLKLQTKTIKV 78 Score = 34.7 bits (78), Expect = 0.10, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 6/78 (7%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCG------FVQYVDRLSAEAAIA 366 T + + L +T+DE ++ F G I K+ K G FV Y D A+ AI Sbjct: 5 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 64 Query: 367 GMQGFPIANSRVRLSWGR 384 + G + +++S+ R Sbjct: 65 TLNGLKLQTKTIKVSYAR 82 >2CJK-A nrPDB Length = 167 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 1/51 (1%) Query: 162 NCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKF 212 +C +F+G L + TE L E F +Y + + KI+ D TG S+G+GF+ F Sbjct: 3 SCKMFIGGLNWDTTEDNLREYF-GKYGTVTDLKIMKDPATGRSRGFGFLSF 52 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 19/52 (36%), Positives = 35/52 (67%), Gaps = 1/52 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSD 216 IFVG + P+V + FE F +++ + A+++ D+ TG S+G+GFV + ++D Sbjct: 90 IFVGGIGPDVRPKE-FEEFFSQWGTIIDAQLMLDKDTGQSRGFGFVTYDSAD 140 Score = 36.2 bits (82), Expect = 0.033, Method: Composition-based stats. Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 4/42 (9%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKI----PVGKCCGF 352 +FIGGL+ TED LR YF +GT+ +KI G+ GF Sbjct: 6 MFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGF 47 >6FF4-1 nrPDB Length = 322 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 IF+G L +TE + +F ++Y + +V D+ TG SKG+ F+ + + LA+ Sbjct: 38 IFLGGLPYELTEGDIICVF-SQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDN 96 Query: 225 MQGVFLNGRAIKVGPTS 241 G+ + GR I+V S Sbjct: 97 FNGIKIKGRTIRVDHVS 113 Score = 33.1 bits (74), Expect = 0.33, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 6/72 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCG------FVQYVDRLSAEAAIAGM 368 +F+GGL +TE ++ F +G IV + + K G F+ Y D+ S A+ Sbjct: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97 Query: 369 QGFPIANSRVRL 380 G I +R+ Sbjct: 98 NGIKIKGRTIRV 109 >6GD1-A nrPDB Length = 206 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 IF+ +L + E L+++F + + ++ K++ D T KG+GFV TN +E +A++ Sbjct: 125 CIFIYNLGQDADEGILWQMF-GPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIA 183 Query: 224 EMQGVFLNGRAIKV 237 + G L + ++V Sbjct: 184 SLNGYRLGDKILQV 197 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 12/90 (13%) Query: 304 LNHFTDPN------NTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP----VGKC--CG 351 L F D N +FI L E L F PFG + VK+ KC G Sbjct: 109 LKEFLDANLAGSAMGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFG 168 Query: 352 FVQYVDRLSAEAAIAGMQGFPIANSRVRLS 381 FV + A AIA + G+ + + +++S Sbjct: 169 FVTMTNYEEAAMAIASLNGYRLGDKILQVS 198 >6D0Y-A nrPDB Length = 176 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 31/133 (23%), Positives = 64/133 (48%), Gaps = 6/133 (4%) Query: 112 DFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLA 171 +FP AA+ + G+L + ++L+ + +N +C+++VG+L+ Sbjct: 10 EFPGRLEAADPM-SGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLS 68 Query: 172 PNVTESQLFELFINRYASTSHAKIVH--DQVTGMSKGYGFVKFTNSDEQQLALSEMQGVF 229 TE Q++ELF S KI+ D++ + G+ FV++ + + + A+ + G Sbjct: 69 FYTTEEQIYELFSK---SGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTR 125 Query: 230 LNGRAIKVGPTSG 242 L+ R I+ +G Sbjct: 126 LDDRIIRTDWDAG 138 Score = 37.0 bits (84), Expect = 0.022, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 6/78 (7%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK----CCG--FVQYVDRLSAEAA 364 + T+++G LS TE+++ F G I + + + K CG FV+Y R AE A Sbjct: 58 KSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENA 117 Query: 365 IAGMQGFPIANSRVRLSW 382 + + G + + +R W Sbjct: 118 MRYINGTRLDDRIIRTDW 135 >5ZWM-X nrPDB Length = 148 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 28/108 (25%), Positives = 54/108 (50%), Gaps = 7/108 (6%) Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 +N I++G+L +TE + +F + Y + D+ TG S+G+ ++K+ + L Sbjct: 29 DNAYIYIGNLNRELTEGDILTVF-SEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTIL 87 Query: 221 ALSEMQGVFLNGRAIKVGPT------SGQQQHVSGNNDYNRSSSSLNN 262 A+ + G + GRA+K+ T S Q+ + + + +R S NN Sbjct: 88 AVDNLNGFKIGGRALKIDHTFYRPKRSLQKYYEAVKEELDRDIVSKNN 135 Score = 29.3 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 6/76 (7%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP----VGKCCGF--VQYVDRLSAEAA 364 +N ++IG L+ +TE ++ F +G V V + G+ GF ++Y D+ S A Sbjct: 29 DNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTILA 88 Query: 365 IAGMQGFPIANSRVRL 380 + + GF I +++ Sbjct: 89 VDNLNGFKIGGRALKI 104 >4LMZ-A nrPDB Length = 180 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 6/80 (7%) Query: 296 YPVQQQPSLNHFTDP-NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG-----KC 349 +P+Q +P+ + ++ + +FIG +S E+++R F PFG I +I G + Sbjct: 83 HPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRG 142 Query: 350 CGFVQYVDRLSAEAAIAGMQ 369 C FV + R A+ AI M Sbjct: 143 CAFVTFSTRAMAQNAIKAMH 162 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/100 (23%), Positives = 46/100 (46%), Gaps = 11/100 (11%) Query: 309 DPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI--------PVGKCCGFVQYVDR-- 358 DP+ +F+G + +E EL+ F+P+G + + + P K C FV + R Sbjct: 5 DPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKA 64 Query: 359 -LSAEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAML 397 L A+ A+ ++ P + +++ S K A+ + + Sbjct: 65 ALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLF 104 >1SXL-A nrPDB Length = 97 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 1/75 (1%) Query: 158 KSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE 217 +S + +++V +L +T+ QL +F +Y S I+ D++TG +G FV++ +E Sbjct: 9 ESIKDTNLYVTNLPRTITDDQLDTIF-GKYGSIVQKNILRDKLTGRPRGVAFVRYNKREE 67 Query: 218 QQLALSEMQGVFLNG 232 Q A+S + V G Sbjct: 68 AQEAISALNNVIPEG 82 Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 6/63 (9%) Query: 312 NTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCG------FVQYVDRLSAEAAI 365 +T +++ L +T+D+L F +G+IV I K G FV+Y R A+ AI Sbjct: 13 DTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAI 72 Query: 366 AGM 368 + + Sbjct: 73 SAL 75 >5MMM-v nrPDB Length = 260 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 40/192 (20%), Positives = 80/192 (41%), Gaps = 18/192 (9%) Query: 50 GTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYC 109 G +LY+G++ + + +R I G I +M++ R + Sbjct: 80 GEGARRLYVGNIPRNLNNDELRTIVEEHGAIEI-AEVMYDKYSGRSRR----------FG 128 Query: 110 FVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCS----I 165 FV + ANA+++ + +K+K+N + + + + Sbjct: 129 FVTM-KTVEDANAVIEK-LNDTEIGGRKIKVNITEKPLEGMDIATTQAEDSQFVESPYKV 186 Query: 166 FVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEM 225 ++G+LA VT ++L + F + AK+ T S G+GFV F++ +E + A+ + Sbjct: 187 YIGNLAKTVT-NELLKDFFSEKGKVLGAKVQRTPGTSKSNGFGFVSFSSEEEVEAAIQAL 245 Query: 226 QGVFLNGRAIKV 237 L G+ I+V Sbjct: 246 NNSVLEGQKIRV 257 Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust. Identities = 17/77 (22%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 ++VG++ N+ +L + + + A++++D+ +G S+ +GFV ++ + + Sbjct: 86 LYVGNIPRNLNNDEL-RTIVEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANAVIEK 144 Query: 225 MQGVFLNGRAIKVGPTS 241 + + GR IKV T Sbjct: 145 LNDTEIGGRKIKVNITE 161 >2SXL-A nrPDB Length = 88 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Query: 160 GNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQ 219 +N ++ V L ++T+ +L+ LF + +I+ D TG S GY FV FT+ + Q Sbjct: 1 ASNTNLIVNYLPQDMTDRELYALF-RAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQ 59 Query: 220 LALSEMQGVFLNGRAIKV 237 A+ + G+ + + +KV Sbjct: 60 RAIKVLNGITVRNKRLKV 77 >2MYF-A nrPDB Length = 89 Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 23/88 (26%), Positives = 45/88 (51%), Gaps = 7/88 (7%) Query: 305 NHFTDPNNTTV-FIGGLSSLVTEDELRAYFQPFGTIVYVKIPV------GKCCGFVQYVD 357 +H +D N T + F+GG+ + E L F FG I +++P+ + FV+YV+ Sbjct: 2 SHMSDNNATDILFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVE 61 Query: 358 RLSAEAAIAGMQGFPIANSRVRLSWGRS 385 A+ A+ M F + R+ +++ ++ Sbjct: 62 VDDAKHALYNMNNFELNGKRIHVNYSKT 89 Score = 37.4 bits (85), Expect = 0.018, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 43/81 (53%), Gaps = 3/81 (3%) Query: 159 SGNNCS--IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSD 216 S NN + +FVG + + E L+++F + + + ++ + T ++G+ FV++ D Sbjct: 5 SDNNATDILFVGGIDETIDEKSLYDIF-SSFGDIRNIEVPLNMTTKKNRGFAFVEYVEVD 63 Query: 217 EQQLALSEMQGVFLNGRAIKV 237 + + AL M LNG+ I V Sbjct: 64 DAKHALYNMNNFELNGKRIHV 84 Score = 29.3 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 13/81 (16%) Query: 44 ASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEA-NINVRMMWNNTLNNGSRSSMGP 102 S++S + L++G +D T D+ ++ I++S G+ NI V + +M Sbjct: 1 GSHMSDNNATDILFVGGIDETIDEKSLYDIFSSFGDIRNIEVPL------------NMTT 48 Query: 103 KNNQGYCFVDFPSSTHAANAL 123 K N+G+ FV++ A +AL Sbjct: 49 KKNRGFAFVEYVEVDDAKHAL 69 >4PKD-B nrPDB Length = 279 Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 8/85 (9%) Query: 308 TDPNNTTVFIGGLSSLVTEDELR----AYFQPFGTIVYVKIPVG---KCCGFVQYVDRLS 360 T PN+T ++I L+ + +DEL+ A F FG I+ + + + FV + + S Sbjct: 5 TRPNHT-IYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSS 63 Query: 361 AEAAIAGMQGFPIANSRVRLSWGRS 385 A A+ MQGFP + +R+ + ++ Sbjct: 64 ATNALRSMQGFPFYDKPMRIQYAKT 88 Score = 36.6 bits (83), Expect = 0.031, Method: Compositional matrix adjust. Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++FV + + TES+L F Y +V+ + +G +GY F+++ + + A Sbjct: 168 TLFVARVNYDTTESKLRREF-EVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYK 226 Query: 224 EMQGVFLNGRAIKVGPTSGQ 243 G ++GR + V G+ Sbjct: 227 HADGKKIDGRRVLVDVERGR 246 >2KN4-A nrPDB Length = 158 Score = 38.5 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 S+ V +L + L +F +Y I D+ T S+G+ FV+F + + + A+ Sbjct: 72 SLKVDNLTYRTSPDTLRRVF-EKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 130 Query: 224 EMQGVFLNGRAIKV 237 M G L+GR ++V Sbjct: 131 AMDGAVLDGRELRV 144 Score = 31.6 bits (70), Expect = 0.95, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 6/81 (7%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCC------GFVQYVDRLSAEAAIA 366 T++ + L+ + D LR F+ +G + V IP + FV++ D+ AE A+ Sbjct: 71 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 130 Query: 367 GMQGFPIANSRVRLSWGRSAK 387 M G + +R+ R + Sbjct: 131 AMDGAVLDGRELRVQMARYGR 151 >2LEC-A nrPDB Length = 135 Score = 38.5 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 S+ V +L + L +F +Y I D+ T S+G+ FV+F + + + A+ Sbjct: 49 SLKVDNLTYRTSPDTLRRVF-EKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 107 Query: 224 EMQGVFLNGRAIKV 237 M G L+GR ++V Sbjct: 108 AMDGAVLDGRELRV 121 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 6/81 (7%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCC------GFVQYVDRLSAEAAIA 366 T++ + L+ + D LR F+ +G + V IP + FV++ D+ AE A+ Sbjct: 48 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 107 Query: 367 GMQGFPIANSRVRLSWGRSAK 387 M G + +R+ R + Sbjct: 108 AMDGAVLDGRELRVQMARYGR 128 >1D9A-A nrPDB Length = 85 Score = 38.5 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 40/66 (60%), Gaps = 1/66 (1%) Query: 162 NCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLA 221 + +++V L +++ ++ +LF ++Y ++I+ DQ TG+S+G GF++F E + A Sbjct: 1 DANLYVSGLPKTMSQKEMEQLF-SQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEA 59 Query: 222 LSEMQG 227 + + G Sbjct: 60 IKGLNG 65 >6QX9-1A nrPDB Length = 282 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 8/85 (9%) Query: 308 TDPNNTTVFIGGLSSLVTEDELR----AYFQPFGTIVYVKIPVG---KCCGFVQYVDRLS 360 T PN+T ++I L+ + +DEL+ A F FG I+ + + + FV + + S Sbjct: 6 TRPNHT-IYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSS 64 Query: 361 AEAAIAGMQGFPIANSRVRLSWGRS 385 A A+ MQGFP + +R+ + ++ Sbjct: 65 ATNALRSMQGFPFYDKPMRIQYAKT 89 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Query: 293 QFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKC-CG 351 Q + P Q P+ +P N +F+ L E L F F V++ G+ Sbjct: 188 QQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIA 247 Query: 352 FVQYVDRLSAEAAIAGMQGFPIA-NSRVRLSWGRS 385 FV++ + + A AA +QGF I N+ +++S+ + Sbjct: 248 FVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK 282 >6ASO-A nrPDB Length = 424 Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 34/59 (57%), Gaps = 8/59 (13%) Query: 315 VFIGGLSS-LVTEDELRAYFQPFGTIVYVKIPVGK-------CCGFVQYVDRLSAEAAI 365 + I LS+ L+ E+ LR F+ FG+I + IP G+ CC F+ + ++ SAE A+ Sbjct: 186 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL 244 >1X5P-A nrPDB Length = 97 Score = 37.4 bits (85), Expect = 0.018, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 2/63 (3%) Query: 329 LRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAKQ 388 LR F PFG I+ + + + C FV Y SA+ A+A + G + + +++++ R KQ Sbjct: 30 LRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQVESVQLKVNIAR--KQ 87 Query: 389 TAL 391 L Sbjct: 88 PML 90 >2CPE-A nrPDB Length = 113 Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 14/90 (15%) Query: 309 DPNNTTVFIGGLSSLVTEDELRAYFQPFGTI------------VYVKIPVGKCCG--FVQ 354 D +N+ +++ GL+ VT D+L +F+ G + +Y+ GK G V Sbjct: 12 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 71 Query: 355 YVDRLSAEAAIAGMQGFPIANSRVRLSWGR 384 Y D +A+AA+ G S++++S R Sbjct: 72 YEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 101 >5OO6-B nrPDB Length = 158 Score = 37.0 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 46/83 (55%), Gaps = 5/83 (6%) Query: 162 NCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVH--DQVTGMSKGYGFVKFTNSDEQQ 219 +C+++VG+L+ TE Q++ELF S KI+ D++ + G+ FV++ + + + Sbjct: 41 SCTLYVGNLSFYTTEEQIYELF---SKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAE 97 Query: 220 LALSEMQGVFLNGRAIKVGPTSG 242 A+ + G L+ R I+ +G Sbjct: 98 NAMRYINGTRLDDRIIRTDWDAG 120 Score = 35.4 bits (80), Expect = 0.059, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 6/81 (7%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK----CCG--FVQYVDRLSAEAAIAG 367 T+++G LS TE+++ F G I + + + K CG FV+Y R AE A+ Sbjct: 43 TLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRY 102 Query: 368 MQGFPIANSRVRLSWGRSAKQ 388 + G + + +R W K+ Sbjct: 103 INGTRLDDRIIRTDWDAGFKE 123 >6GML-X nrPDB Length = 404 Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 31/56 (55%) Query: 329 LRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGR 384 LR F PFG I+ + + + C FV Y SA+ A+A + G + + +++++ R Sbjct: 300 LRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQVESVQLKVNIAR 355 >3CW1-K nrPDB Length = 216 Score = 37.0 bits (84), Expect = 0.023, Method: Compositional matrix adjust. Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++FV + + TES+L F Y +V+ + +G +GY F+++ + + A Sbjct: 104 TLFVARVNYDTTESKLRREF-EVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYK 162 Query: 224 EMQGVFLNGRAIKVGPTSGQ 243 G ++GR + V G+ Sbjct: 163 HADGKKIDGRRVLVDVERGR 182 >1H6K-X nrPDB Length = 98 Score = 36.6 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 12/86 (13%) Query: 162 NCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSK-----GYGFVKFTNSD 216 +C+++VG+L+ TE Q++ELF S + + + G+ K G+ FV++ + Sbjct: 18 SCTLYVGNLSFYTTEEQIYELF-------SKSGDIKKIIMGLDKMKTACGFCFVEYYSRA 70 Query: 217 EQQLALSEMQGVFLNGRAIKVGPTSG 242 + + A+ + G L+ R I+ +G Sbjct: 71 DAENAMRYINGTRLDDRIIRTDWDAG 96 Score = 36.2 bits (82), Expect = 0.037, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 5/74 (6%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK---CCG--FVQYVDRLSAEAAIAGM 368 T+++G LS TE+++ F G I + + + K CG FV+Y R AE A+ + Sbjct: 20 TLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKTACGFCFVEYYSRADAENAMRYI 79 Query: 369 QGFPIANSRVRLSW 382 G + + +R W Sbjct: 80 NGTRLDDRIIRTDW 93 >6QX9-1K nrPDB Length = 437 Score = 36.2 bits (82), Expect = 0.033, Method: Compositional matrix adjust. Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++FV + + TES+L F Y +V+ + +G +GY F+++ + + A Sbjct: 104 TLFVARVNYDTTESKLRREF-EVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYK 162 Query: 224 EMQGVFLNGRAIKV 237 G ++GR + V Sbjct: 163 HADGKKIDGRRVLV 176 >2DH8-A nrPDB Length = 105 Score = 36.2 bits (82), Expect = 0.034, Method: Composition-based stats. Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 2/85 (2%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 +FVG L + T+ L F ++Y I+ D+ T S+G+GFVKF + + L+ Sbjct: 19 LFVGGLDWSTTQETLRSYF-SQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLAS 77 Query: 225 MQGVFLNGRAIKVGPTSGQQQHVSG 249 L+GR I P + + SG Sbjct: 78 RPHT-LDGRNIDPKPCTPRGMQPSG 101 Score = 29.6 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 6/49 (12%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCC------GFVQYVD 357 +F+GGL T++ LR+YF +G +V I K GFV++ D Sbjct: 19 LFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKD 67 >5EV3-A nrPDB Length = 201 Score = 36.2 bits (82), Expect = 0.038, Method: Compositional matrix adjust. Identities = 30/143 (20%), Positives = 66/143 (46%), Gaps = 14/143 (9%) Query: 105 NQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKL----NWATSSYSNSNNSL------ 154 ++ + F++F S A+ +G++ F + LK+ ++ + N S+ Sbjct: 54 DKNFAFLEFRSVDETTQAMAFDGII---FQGQSLKIRRPHDYQPLPGMSENPSVYVPGVV 110 Query: 155 NNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTN 214 + V + +F+G L + + Q+ EL + + +V D TG+SKGY F ++ + Sbjct: 111 STVVPDSAHKLFIGGLPNYLNDDQVKEL-LTSFGPLKAFNLVKDSATGLSKGYAFCEYVD 169 Query: 215 SDEQQLALSEMQGVFLNGRAIKV 237 + A++ + G+ L + + V Sbjct: 170 INVTDQAIAGLNGMQLGDKKLLV 192 Score = 32.7 bits (73), Expect = 0.45, Method: Compositional matrix adjust. Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIP------VGKCCGFVQYVDRLSAEAAIAGM 368 +FIGGL + + +D+++ FG + + + K F +YVD + AIAG+ Sbjct: 121 LFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGL 180 Query: 369 QGFPIANSRV 378 G + + ++ Sbjct: 181 NGMQLGDKKL 190 >2BZ2-A nrPDB Length = 121 Score = 36.2 bits (82), Expect = 0.039, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 2/63 (3%) Query: 329 LRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAKQ 388 LR F PFG I+ + + + C FV Y SA+ A+A + G + + +++++ R KQ Sbjct: 54 LRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQVESVQLKVNIAR--KQ 111 Query: 389 TAL 391 L Sbjct: 112 PML 114 >5EN1-A nrPDB Length = 184 Score = 36.2 bits (82), Expect = 0.039, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSD 216 +FVG + + E L + F Y +I+ D+ +G +G+GFV F + D Sbjct: 102 KLFVGGIKEDTEEHHLRDYF-EEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD 153 Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 6/59 (10%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTI---VYVKIPVGKCC---GFVQYVDRLSAEAAIAG 367 +FIGGLS TE+ LR Y++ +G + V ++ P K GFV + +AA+A Sbjct: 12 LFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAA 70 Score = 28.1 bits (61), Expect = 9.7, Method: Compositional matrix adjust. Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 +F+G L+ TE L + ++ + ++ D + S+G+GFV F++ E A++ Sbjct: 11 KLFIGGLSFETTEESLRNYY-EQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMA 69 >5MQF-o nrPDB Length = 301 Score = 36.2 bits (82), Expect = 0.040, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 ++VG LA V + L FI + + +I D T +G+ FV+F +++ A+ Sbjct: 8 LYVGGLAEEVDDKVLHAAFIP-FGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDN 66 Query: 225 MQGVFLNGRAIKV 237 M L GR I+V Sbjct: 67 MNESELFGRTIRV 79 Score = 35.0 bits (79), Expect = 0.088, Method: Compositional matrix adjust. Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 6/80 (7%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAEAAIAG 367 +++GGL+ V + L A F PFG I ++IP+ + FV++ A AAI Sbjct: 7 VLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDN 66 Query: 368 MQGFPIANSRVRLSWGRSAK 387 M + +R++ + + Sbjct: 67 MNESELFGRTIRVNLAKPMR 86 >2RS2-A nrPDB Length = 109 Score = 35.8 bits (81), Expect = 0.045, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTN 214 + C +F+G L+ T+ L E F ++ ++ D +T S+G+GFV F + Sbjct: 24 SGCKMFIGGLSWQTTQEGLREYF-GQFGEVKECLVMRDPLTKRSRGFGFVTFMD 76 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 6/58 (10%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTI---VYVKIPVGKCC---GFVQYVDRLSAEAAIA 366 +FIGGLS T++ LR YF FG + + ++ P+ K GFV ++D+ + +A Sbjct: 28 MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLA 85 >1UAW-A nrPDB Length = 77 Score = 35.8 bits (81), Expect = 0.047, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTN 214 C +F+G L+ T+ L E F ++ ++ D +T S+G+GFV F + Sbjct: 1 CKMFIGGLSWQTTQEGLREYF-GQFGEVKECLVMRDPLTKRSRGFGFVTFMD 51 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 6/58 (10%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTI---VYVKIPVGKCC---GFVQYVDRLSAEAAIA 366 +FIGGLS T++ LR YF FG + + ++ P+ K GFV ++D+ + +A Sbjct: 3 MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLA 60 >2CQB-A nrPDB Length = 102 Score = 35.4 bits (80), Expect = 0.061, Method: Composition-based stats. Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 12/89 (13%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 ++VG LA V + L FI + + +I D T +G+ FV+F +++ A+ Sbjct: 15 LYVGGLAEEVDDKVLHAAFIP-FGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDN 73 Query: 225 MQGVFLNGRAIKV-----------GPTSG 242 M L GR I+V GP+SG Sbjct: 74 MNESELFGRTIRVNLAKPMRIKESGPSSG 102 Score = 33.1 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 6/79 (7%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAEAAIAGM 368 +++GGL+ V + L A F PFG I ++IP+ + FV++ A AAI M Sbjct: 15 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 74 Query: 369 QGFPIANSRVRLSWGRSAK 387 + +R++ + + Sbjct: 75 NESELFGRTIRVNLAKPMR 93 >6C8U-1 nrPDB Length = 115 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 6/68 (8%) Query: 305 NHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTI---VYVKIPVGKCC---GFVQYVDR 358 N + N +FIGGLS + D LR YF FG I + ++ P K GFV + D Sbjct: 17 NLYFQSNAGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADP 76 Query: 359 LSAEAAIA 366 S + + Sbjct: 77 ASVDKVLG 84 Score = 29.3 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTN 214 N +F+G L+ + L + F +++ ++ D T S+G+GFV F + Sbjct: 23 NAGKMFIGGLSWQTSPDSLRDYF-SKFGEIRECMVMRDPTTKRSRGFGFVTFAD 75 >6AH0-p nrPDB Length = 225 Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust. Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 7/81 (8%) Query: 312 NTTVFIGGLSSLVTEDELR----AYFQPFGTIV-YVKIPVGKCCG--FVQYVDRLSAEAA 364 N T++I ++ + ++EL+ A F FG +V V + K G FV + + S+ A Sbjct: 6 NHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNA 65 Query: 365 IAGMQGFPIANSRVRLSWGRS 385 + +QGFP +R+ + ++ Sbjct: 66 LRQLQGFPFYGKPMRIQYAKT 86 >6EM1-o nrPDB Length = 220 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 I+V L E +L + F ++ ++ ++ TG S+ YGF++F N ++ +A Sbjct: 93 IYVSRLPHGFHEKELSKYFA-QFGDLKEVRLARNKKTGNSRHYGFLEFVNKEDAMIAQES 151 Query: 225 MQGVFLNGRAIKV 237 M L G ++V Sbjct: 152 MNNYLLMGHLLQV 164 >5X3Y-A nrPDB Length = 96 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSD 216 IFVG L+ N T + F ++ A ++ D+ T +G+GFV F + D Sbjct: 7 IFVGGLSVNTTVEDVKHYF-EQFGKVDDAMLMFDKTTNRHRGFGFVTFESED 57 Score = 28.9 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 18/25 (72%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTI 339 +F+GGLS T ++++ YF+ FG + Sbjct: 7 IFVGGLSVNTTVEDVKHYFEQFGKV 31 >2MST-A nrPDB Length = 75 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSD 216 IFVG L+ N T + F ++ A ++ D+ T +G+GFV F + D Sbjct: 2 IFVGGLSVNTTVEDVKHYF-EQFGKVDDAMLMFDKTTNRHRGFGFVTFESED 52 Score = 28.9 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 18/25 (72%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTI 339 +F+GGLS T ++++ YF+ FG + Sbjct: 2 IFVGGLSVNTTVEDVKHYFEQFGKV 26 >3MDF-A nrPDB Length = 85 Score = 34.3 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 ++VG LA V + L FI + + +I D T +G+ FV+F +++ A+ Sbjct: 10 LYVGGLAEEVDDKVLHAAFIP-FGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDN 68 Query: 225 MQGVFLNGRAIKV 237 M L GR I+V Sbjct: 69 MNESELFGRTIRV 81 Score = 33.5 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 6/76 (7%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAEAAIAGM 368 +++GGL+ V + L A F PFG I ++IP+ + FV++ A AAI M Sbjct: 10 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 69 Query: 369 QGFPIANSRVRLSWGR 384 + +R++ + Sbjct: 70 NESELFGRTIRVNLAK 85 >2KU7-A nrPDB Length = 140 Score = 34.3 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 ++VG LA V + L FI + + +I D T +G+ FV+F +++ A+ Sbjct: 66 LYVGGLAEEVDDKVLHAAFIP-FGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDN 124 Query: 225 MQGVFLNGRAIKV 237 M L GR I+V Sbjct: 125 MNESELFGRTIRV 137 Score = 33.1 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 6/73 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAEAAIAGM 368 +++GGL+ V + L A F PFG I ++IP+ + FV++ A AAI M Sbjct: 66 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 125 Query: 369 QGFPIANSRVRLS 381 + +R++ Sbjct: 126 NESELFGRTIRVN 138 >2CQ3-A nrPDB Length = 103 Score = 34.3 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 11/50 (22%) Query: 204 SKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKV-----------GPTSG 242 SKG+GFV F NS + A ++ G + GR I+V GP+SG Sbjct: 54 SKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNSGPSSG 103 >2DH9-A nrPDB Length = 89 Score = 34.3 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 10/91 (10%) Query: 159 SGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQ 218 S + IFV +L + T L + F N +A I + G SKG G VKF + + Sbjct: 2 SSGSSGIFVRNLPFDFTWKMLKDKF-NECGHVLYADIKMEN--GKSKGCGVVKFESPEVA 58 Query: 219 QLALSEMQGVFLNGRAIKV-------GPTSG 242 + A M G+ L+GR I V GP+SG Sbjct: 59 ERACRMMNGMKLSGREIDVRIDRNASGPSSG 89 >1X4A-A nrPDB Length = 109 Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPV---GKCCGFVQYVDRLSAEAAIAG 367 N+ +++G L + ++ F +G I + + G FV++ D AE A+ G Sbjct: 21 NDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYG 80 Query: 368 MQGFPIANSRVRLSWGRSAKQTA 390 G+ R+R+ + RS + T Sbjct: 81 RDGYDYDGYRLRVEFPRSGRGTG 103 >2ERR-A nrPDB Length = 109 Score = 33.5 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 15/40 (37%), Positives = 23/40 (57%) Query: 204 SKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQ 243 SKG+GFV F NS + A ++ G + GR I+V + + Sbjct: 68 SKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATAR 107 >3N9U-C nrPDB Length = 156 Score = 33.5 bits (75), Expect = 0.24, Method: Compositional matrix adjust. Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 3/85 (3%) Query: 161 NNCSIFVGDLAPNVTESQLFELF--INRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQ 218 +++VG + T+ QL ++ I Y K ++ G SKGY V + + Sbjct: 54 RRAAVYVGSFSWWTTDQQLIQVIRSIGVY-DVVELKFAENRANGQSKGYAEVVVASENSV 112 Query: 219 QLALSEMQGVFLNGRAIKVGPTSGQ 243 L + G LNG + V P + Q Sbjct: 113 HKLLELLPGKVLNGEKVDVRPATRQ 137 >2DGS-A nrPDB Length = 99 Score = 33.1 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 10/59 (16%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKI--------PVGKCCGFVQYVDRLSAEAAI 365 +F+GG+ E ELR YF+ FG + V + P G GF+ + D S + A+ Sbjct: 13 IFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRG--FGFITFEDEQSVDQAV 69 Score = 33.1 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 3/56 (5%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 IFVG + N E++L E F ++ + +++D +G+GF+ F DEQ + Sbjct: 13 IFVGGIPHNCGETELREYF-KKFGVVTEVVMIYDAEKQRPRGFGFITF--EDEQSV 65 >1RK8-A nrPDB Length = 165 Score = 32.7 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 +FV + E ++ E F + Y + + D+ TG SKGY V++ + A Sbjct: 75 LFVTSIHEEAQEDEIQEKFCD-YGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEA 133 Query: 225 MQGVFLNGRAIKV 237 + G + G+ I+V Sbjct: 134 LNGAEIMGQTIQV 146 >1OO0-B nrPDB Length = 110 Score = 32.7 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 +FV + E ++ E F + Y + + D+ TG SKGY V++ + A Sbjct: 29 LFVTSIHEEAQEDEIQEKFCD-YGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEA 87 Query: 225 MQGVFLNGRAIKV 237 + G + G+ I+V Sbjct: 88 LNGAEIMGQTIQV 100 >2MGZ-B nrPDB Length = 105 Score = 32.7 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 2/73 (2%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 IFVG L + ++ L E F ++ A ++ D+ T S+GYGFV + + A + Sbjct: 19 IFVGGLPYHTSDKTLHEYF-EQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACKD 77 Query: 225 MQGVFLNGRAIKV 237 + ++GR V Sbjct: 78 PNPI-IDGRKANV 89 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 6/58 (10%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCC------GFVQYVDRLSAEAA 364 T +F+GGL ++ L YF+ FG I + + GFV DR SAE A Sbjct: 17 TKIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERA 74 >5YVG-X nrPDB Length = 528 Score = 32.7 bits (73), Expect = 0.42, Method: Compositional matrix adjust. Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 14/86 (16%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTI------------VYVKIPVGKCCG--FVQYV 356 +N T+F+ GL VT + + YF+ G I +Y GK G V + Sbjct: 285 DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 344 Query: 357 DRLSAEAAIAGMQGFPIANSRVRLSW 382 D SA+AAI G + + +++S+ Sbjct: 345 DPPSAKAAIDWFDGKEFSGNPIKVSF 370 >4ZKA-A nrPDB Length = 100 Score = 32.3 bits (72), Expect = 0.50, Method: Composition-based stats. Identities = 15/40 (37%), Positives = 23/40 (57%) Query: 204 SKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQ 243 SKG+GFV F NS + A ++ G + GR I+V + + Sbjct: 47 SKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATAR 86 >5LJ5-M nrPDB Length = 339 Score = 32.0 bits (71), Expect = 0.60, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 9/66 (13%) Query: 312 NTTVFIGGLSSLV---------TEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAE 362 N T+++GG+ + E +R F G I ++ K CGFV++ + +AE Sbjct: 134 NKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYVESKNCGFVKFKYQANAE 193 Query: 363 AAIAGM 368 A M Sbjct: 194 FAKEAM 199 >2EVZ-A nrPDB Length = 229 Score = 32.0 bits (71), Expect = 0.63, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 7/77 (9%) Query: 162 NCSIFVGDLAPN-VTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 N + V +L P VT LF LF Y KI+ ++ K V+ + ++ QL Sbjct: 34 NSVLLVSNLNPERVTPQSLFILF-GVYGDVQRVKILFNK-----KENALVQMADGNQAQL 87 Query: 221 ALSEMQGVFLNGRAIKV 237 A+S + G L+G+ I++ Sbjct: 88 AMSHLNGHKLHGKPIRI 104 >1QM9-A nrPDB Length = 198 Score = 31.6 bits (70), Expect = 0.78, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 7/77 (9%) Query: 162 NCSIFVGDLAPN-VTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 N + V +L P VT LF LF Y KI+ ++ K V+ + ++ QL Sbjct: 3 NSVLLVSNLNPERVTPQSLFILF-GVYGDVQRVKILFNK-----KENALVQMADGNQAQL 56 Query: 221 ALSEMQGVFLNGRAIKV 237 A+S + G L+G+ I++ Sbjct: 57 AMSHLNGHKLHGKPIRI 73 >6D6V-H nrPDB Length = 542 Score = 31.6 bits (70), Expect = 0.84, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 12/76 (15%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 LY+ L P K T+ I+ + NIN+ + N+ L QG+ F++F S Sbjct: 249 LYIDFLPPKCSKQTLVSIFGNFRIININLPLQKNSQL------------CQGFAFIEFFS 296 Query: 116 STHAANALLKNGMLIP 131 A AL+ IP Sbjct: 297 EEEANQALITKNSSIP 312 >2CQH-A nrPDB Length = 93 Score = 31.6 bits (70), Expect = 0.95, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 19/90 (21%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 +++G+L+P VT L +LF +R + QV + GY FV + + + A+ Sbjct: 11 LYIGNLSPAVTADDLRQLFGDRKLPLA------GQVL-LKSGYAFVDYPDQNWAIRAIET 63 Query: 225 MQG-VFLNGRAIKV-----------GPTSG 242 + G V L+G+ ++V GP+SG Sbjct: 64 LSGKVELHGKIMEVDYSVSKKLRSSGPSSG 93 >2DGP-A nrPDB Length = 106 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 9/81 (11%) Query: 309 DPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI------PVGKCCGFVQYVDR---L 359 D + +FIG + + E +L+ F+ FG I + + + K C F+ Y +R L Sbjct: 10 DHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESAL 69 Query: 360 SAEAAIAGMQGFPIANSRVRL 380 A++A+ + P N +++ Sbjct: 70 KAQSALHEQKTLPGMNRPIQV 90 >2MKI-A nrPDB Length = 203 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 12/26 (46%), Positives = 18/26 (69%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIV 340 VF+GGL + EDE+ A F+ FG ++ Sbjct: 15 VFVGGLPPDIDEDEITASFRRFGPLI 40 >3U1M-A nrPDB Length = 240 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 9/67 (13%) Query: 311 NNTTVFIGGLSSLV---------TEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSA 361 N T+++GG+ + E +R F G I ++ K CGFV++ + +A Sbjct: 133 KNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYVESKNCGFVKFKYQANA 192 Query: 362 EAAIAGM 368 E A M Sbjct: 193 EFAKEAM 199 >2RUG-A nrPDB Length = 114 Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 13/26 (50%), Positives = 18/26 (69%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIV 340 VF+GGL + EDE+ A F+ FG +V Sbjct: 11 VFVGGLPPDIDEDEITASFRRFGPLV 36 >5YZG-w nrPDB Length = 174 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF------VQYVDRLSAEAAIAGM 368 +F+ G+ TE+++ F +G I + + + + G+ V+Y A+AA+ G+ Sbjct: 75 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 134 Query: 369 QGFPIANSRVRLSW 382 G + + + W Sbjct: 135 NGQDLMGQPISVDW 148 >3EX7-B nrPDB Length = 126 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF------VQYVDRLSAEAAIAGM 368 +F+ G+ TE+++ F +G I + + + + G+ V+Y A+AA+ G+ Sbjct: 25 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 84 Query: 369 QGFPIANSRVRLSW 382 G + + + W Sbjct: 85 NGQDLMGQPISVDW 98 >2J0Q-D nrPDB Length = 109 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF------VQYVDRLSAEAAIAGM 368 +F+ G+ TE+++ F +G I + + + + G+ V+Y A+AA+ G+ Sbjct: 10 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 69 Query: 369 QGFPIANSRVRLSW 382 G + + + W Sbjct: 70 NGQDLMGQPISVDW 83 >2HYI-B nrPDB Length = 91 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF------VQYVDRLSAEAAIAGM 368 +F+ G+ TE+++ F +G I + + + + G+ V+Y A+AA+ G+ Sbjct: 12 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 71 Query: 369 QGFPIANSRVRLSW 382 G + + + W Sbjct: 72 NGQDLMGQPISVDW 85 >1P27-B nrPDB Length = 106 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF------VQYVDRLSAEAAIAGM 368 +F+ G+ TE+++ F +G I + + + + G+ V+Y A+AA+ G+ Sbjct: 26 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 85 Query: 369 QGFPIANSRVRLSW 382 G + + + W Sbjct: 86 NGQDLMGQPISVDW 99 >3NNH-A nrPDB Length = 88 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 11/69 (15%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKI--------PVGKCCGFVQYVDR---LSAEA 363 +F+G + +E +LR F+ +G + + + P K C FV + R L A+ Sbjct: 6 MFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 65 Query: 364 AIAGMQGFP 372 A+ M+ P Sbjct: 66 ALHNMKVLP 74 >1L6J-A nrPDB Length = 425 Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 20/31 (64%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKI 195 +F GDL N+T+ QL E ++ RY T A++ Sbjct: 11 LFPGDLRTNLTDRQLAEEYLYRYGYTRVAEM 41 >2I2Y-A nrPDB Length = 150 Score = 29.3 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 6/84 (7%) Query: 162 NCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLA 221 +C ++VG+L N +++L F Y + + G+ FV+F + + A Sbjct: 73 DCKVYVGNLGNNGNKTELERAF-GYYGPLRSVWVARN-----PPGFAFVEFEDPRDAADA 126 Query: 222 LSEMQGVFLNGRAIKVGPTSGQQQ 245 + E+ G L G ++V ++G+++ Sbjct: 127 VRELDGRTLCGCRVRVELSNGEKR 150 >4WKR-A nrPDB Length = 208 Score = 29.3 bits (64), Expect = 4.6, Method: Compositional matrix adjust. Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 158 KSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE 217 K + +++V L NV S + +F + + + I H + TG KG+ FV+F ++ Sbjct: 120 KDEDERTVYVELLPKNVNHSWIERVF-GKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQ 178 Query: 218 QQLALSEMQGVFLN 231 A+ FLN Sbjct: 179 AAKAIE-----FLN 187 >4F19-A nrPDB Length = 381 Score = 28.1 bits (61), Expect = 9.7, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 23/45 (51%) Query: 221 ALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENV 265 AL + GV G A +G SG + NNDY + + + N+NV Sbjct: 13 ALYQTSGVLTAGFAQYIGVGSGNGKAAFLNNDYTKFQAGVTNKNV 57 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5ZWN-V nrPDB 761 0.0 6R5K-D nrPDB 312 3e-85 6AH0-4 nrPDB 173 2e-43 5MMM-v nrPDB 165 3e-41 5ZWM-4 nrPDB 155 5e-38 1FXL-A nrPDB 148 8e-36 4EGL-A nrPDB 142 4e-34 3NNA-A nrPDB 141 7e-34 1FNX-H nrPDB 140 2e-33 6D0Y-A nrPDB 135 5e-32 4LMZ-A nrPDB 132 3e-31 3SXL-A nrPDB 131 5e-31 6QDV-M nrPDB 113 2e-25 6ID0-O nrPDB 113 2e-25 6FF4-1 nrPDB 109 4e-24 5ZWM-X nrPDB 108 7e-24 2DH7-A nrPDB 105 5e-23 5SZW-A nrPDB 104 7e-23 1P1T-A nrPDB 102 3e-22 2YTC-A nrPDB 101 7e-22 2SXL-A nrPDB 101 9e-22 3HI9-A nrPDB 101 1e-21 4FXV-A nrPDB 100 2e-21 1D8Z-A nrPDB 100 3e-21 6GD1-A nrPDB 98 7e-21 6QX9-R nrPDB 98 1e-20 1SXL-A nrPDB 95 7e-20 2YWK-A nrPDB 94 1e-19 5MDU-A nrPDB 93 4e-19 5ZWN-Q nrPDB 91 8e-19 6G90-B nrPDB 91 1e-18 2CJK-A nrPDB 86 4e-17 2RT3-A nrPDB 85 8e-17 2XS5-A nrPDB 79 4e-15 2XS2-A nrPDB 79 4e-15 Sequences not found previously or not previously below threshold: 5OO6-B nrPDB 125 5e-29 1H6K-X nrPDB 104 1e-22 5EV3-A nrPDB 96 3e-20 1D9A-A nrPDB 86 3e-17 4PKD-B nrPDB 83 2e-16 4CQ1-A nrPDB 82 6e-16 6AH0-p nrPDB 82 7e-16 5MQF-o nrPDB 81 8e-16 5EN1-A nrPDB 80 4e-15 2CQB-A nrPDB 78 7e-15 6QX9-1A nrPDB 78 1e-14 3NNH-A nrPDB 78 1e-14 3MDF-A nrPDB 76 3e-14 2KU7-A nrPDB 76 3e-14 5YZG-w nrPDB 76 4e-14 2EVZ-A nrPDB 76 5e-14 2LEC-A nrPDB 75 8e-14 2KN4-A nrPDB 75 8e-14 3EX7-B nrPDB 74 1e-13 1P27-B nrPDB 74 1e-13 1QM9-A nrPDB 74 1e-13 2J0Q-D nrPDB 73 2e-13 2HYI-B nrPDB 73 2e-13 2MYF-A nrPDB 73 3e-13 2MGZ-B nrPDB 72 6e-13 6ASO-A nrPDB 71 1e-12 2DH8-A nrPDB 70 2e-12 6EM1-o nrPDB 70 2e-12 2DGP-A nrPDB 69 5e-12 2ERR-A nrPDB 69 6e-12 6QX9-1K nrPDB 69 6e-12 3CW1-K nrPDB 69 6e-12 2DGQ-A nrPDB 68 7e-12 2RS2-A nrPDB 68 7e-12 2MKI-A nrPDB 68 7e-12 1UAW-A nrPDB 68 8e-12 1RK8-A nrPDB 68 8e-12 1OO0-B nrPDB 68 8e-12 2CQ3-A nrPDB 68 1e-11 6FYY-r nrPDB 66 4e-11 2DH9-A nrPDB 66 4e-11 6C8U-1 nrPDB 66 4e-11 2I2Y-A nrPDB 66 5e-11 4ZKA-A nrPDB 65 6e-11 2DGS-A nrPDB 65 8e-11 4WKR-A nrPDB 63 3e-10 1X4A-A nrPDB 63 3e-10 2MMY-A nrPDB 63 4e-10 2DO0-A nrPDB 62 7e-10 2CQH-A nrPDB 62 7e-10 2LCW-A nrPDB 58 7e-09 3JB9-k nrPDB 58 8e-09 1X5O-A nrPDB 58 9e-09 3JB9-a nrPDB 58 1e-08 2LA6-A nrPDB 57 2e-08 2CPD-A nrPDB 57 2e-08 5X3Y-A nrPDB 57 2e-08 2MST-A nrPDB 57 2e-08 3JB9-Y nrPDB 57 2e-08 2CPE-A nrPDB 56 4e-08 5O20-A nrPDB 56 5e-08 5O1W-A nrPDB 56 5e-08 2BZ2-A nrPDB 56 5e-08 2F9J-A nrPDB 55 1e-07 5YVG-X nrPDB 54 1e-07 6GML-X nrPDB 54 2e-07 1X5P-A nrPDB 52 6e-07 6D6V-H nrPDB 52 6e-07 6FEC-u nrPDB 51 1e-06 5LJ5-M nrPDB 50 3e-06 3U1M-A nrPDB 50 3e-06 3Q2T-C nrPDB 49 5e-06 2LXI-A nrPDB 48 9e-06 3P6Y-C nrPDB 46 4e-05 3N9U-C nrPDB 46 5e-05 2LKZ-A nrPDB 46 6e-05 6FYY-p nrPDB 45 6e-05 2RUG-A nrPDB 45 8e-05 2KVI-A nrPDB 45 1e-04 3NS5-A nrPDB 45 1e-04 2XNQ-A nrPDB 44 1e-04 2CPI-A nrPDB 43 4e-04 2M2B-A nrPDB 42 5e-04 5OPT-h nrPDB 42 6e-04 5WSG-X nrPDB 42 6e-04 5WU6-A nrPDB 42 7e-04 2MKK-A nrPDB 41 0.001 5K1H-B nrPDB 40 0.003 2E5G-A nrPDB 39 0.003 2NLW-A nrPDB 39 0.003 2KRB-A nrPDB 38 0.008 5OSG-h nrPDB 38 0.009 1JMT-A nrPDB 38 0.011 4YH8-A nrPDB 38 0.015 2AD9-A nrPDB 37 0.017 3S8S-A nrPDB 37 0.024 5Y88-M nrPDB 36 0.049 2MQN-A nrPDB 35 0.081 5Z9X-A nrPDB 34 0.14 2B7M-A nrPDB 34 0.15 3DXB-A nrPDB 34 0.21 2PEH-A nrPDB 33 0.29 4NOX-A nrPDB 33 0.33 2W9X-A nrPDB 33 0.35 3HBX-A nrPDB 33 0.41 2VOD-A nrPDB 33 0.51 2DNR-A nrPDB 32 0.71 3I6D-A nrPDB 31 1.5 2DIU-A nrPDB 30 2.3 1S79-A nrPDB 30 2.6 >5ZWN-V nrPDB Length = 523 Score = 761 bits (1965), Expect = 0.0, Method: Composition-based stats. Identities = 523/523 (100%), Positives = 523/523 (100%) Query: 1 MSYKQTTYYPSRGNLVRNDSSPYTNTISSETNNSSTSVLSLQGASNVSLGTTGNQLYMGD 60 MSYKQTTYYPSRGNLVRNDSSPYTNTISSETNNSSTSVLSLQGASNVSLGTTGNQLYMGD Sbjct: 1 MSYKQTTYYPSRGNLVRNDSSPYTNTISSETNNSSTSVLSLQGASNVSLGTTGNQLYMGD 60 Query: 61 LDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAA 120 LDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAA Sbjct: 61 LDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAA 120 Query: 121 NALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLF 180 NALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLF Sbjct: 121 NALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLF 180 Query: 181 ELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPT 240 ELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPT Sbjct: 181 ELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPT 240 Query: 241 SGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQ 300 SGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQ Sbjct: 241 SGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQ 300 Query: 301 QPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLS 360 QPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLS Sbjct: 301 QPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLS 360 Query: 361 AEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYIPS 420 AEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYIPS Sbjct: 361 AEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYIPS 420 Query: 421 STCEAPVLPDNNVSSTMLPGCQILNYSNPYANANGLGSNNFSFYSNNNATNTQATSLLAD 480 STCEAPVLPDNNVSSTMLPGCQILNYSNPYANANGLGSNNFSFYSNNNATNTQATSLLAD Sbjct: 421 STCEAPVLPDNNVSSTMLPGCQILNYSNPYANANGLGSNNFSFYSNNNATNTQATSLLAD 480 Query: 481 TSSMDLSGTGGQQVIMQGSEAVVNSTNAMLNRLEQGSNGFMFA 523 TSSMDLSGTGGQQVIMQGSEAVVNSTNAMLNRLEQGSNGFMFA Sbjct: 481 TSSMDLSGTGGQQVIMQGSEAVVNSTNAMLNRLEQGSNGFMFA 523 >6R5K-D nrPDB Length = 581 Score = 312 bits (799), Expect = 3e-85, Method: Composition-based stats. Identities = 95/444 (21%), Positives = 168/444 (37%), Gaps = 90/444 (20%) Query: 43 GASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGP 102 G+ + S+ + LY+GDL+P+ + + I++ +G + ++R+ + Sbjct: 31 GSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVS-SIRVCRDAIT---------- 79 Query: 103 KNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNN 162 K + GY +V+F + H A + + ++ W S + SL SGN Sbjct: 80 KTSLGYAYVNF--NDHEAGRKAIEQLNYTPIKGRLCRIMW-----SQRDPSLRKKGSGN- 131 Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 IF+ +L P++ L++ F + + +KI D+ G SKG+GFV F + A+ Sbjct: 132 --IFIKNLHPDIDNKALYDTF-SVFGDILSSKIATDEN-GKSKGFGFVHFEEEGAAKEAI 187 Query: 223 SEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSL-----NNENVDSRFLS------ 271 + G+ LNG+ I V P +++ S + ++L N+E D +F Sbjct: 188 DALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFG 247 Query: 272 ---------------KGQSFLS-------------------NGNN---NMGFKRNHMSQF 294 KG F++ NG K+N Sbjct: 248 PIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHV 307 Query: 295 IYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPV-----GKC 349 + + L +F+ L V +++L F P+GTI K+ K Sbjct: 308 LKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKG 367 Query: 350 CGFVQYVDRLSAEAAIAGMQGFPIANSR--VRLSWGRSAKQTALLQQAMLSNSLQVQQQQ 407 GFV + A AI +A V ++ + +++ L QQ N ++ QQ Sbjct: 368 FGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMRYQQAT 427 Query: 408 ----------PGLQQPN--YGYIP 419 PG P YG +P Sbjct: 428 AAAAAAAAGMPGQFMPPMFYGVMP 451 Score = 123 bits (307), Expect = 3e-28, Method: Composition-based stats. Identities = 53/289 (18%), Positives = 113/289 (39%), Gaps = 42/289 (14%) Query: 140 LNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQ 199 LN + S + ++ S++VGDL P+V+E+ L+++F + S S ++ D Sbjct: 19 LNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIF-SPIGSVSSIRVCRDA 77 Query: 200 VTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKV-----GPTSGQQ--QHVSGNND 252 +T S GY +V F + + + A+ ++ + GR ++ P+ ++ ++ N Sbjct: 78 ITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNL 137 Query: 253 YNRSSSSLNNENVDSRF--------------LSKGQSFLSNGNNNMGFKR-NHMSQFIYP 297 + + + S F SKG F+ + + ++ + Sbjct: 138 HP-DIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLN 196 Query: 298 VQQQPSLNHFTDPNN-----------TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPV 346 Q+ H + T +++ ++S T+++ + F FG IV + Sbjct: 197 GQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEK 256 Query: 347 G-----KCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAKQTA 390 K GFV Y A A+ + + ++ + GR+ K+ Sbjct: 257 DADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYV--GRAQKKNE 303 >6AH0-4 nrPDB Length = 424 Score = 173 bits (437), Expect = 2e-43, Method: Composition-based stats. Identities = 48/184 (26%), Positives = 81/184 (44%), Gaps = 17/184 (9%) Query: 63 PTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSR-SSMGPKN-----NQGYCFVDFPSS 116 P ++N ++ + ++ ++W L G ++ PK+ +QGY FV+F S Sbjct: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64 Query: 117 THAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTE 176 A A+ M+ K +++N A++ N + +IF+G+L P + E Sbjct: 65 EDADYAIKIMNMI--KLYGKPIRVNKASAHNKNLDVG---------ANIFIGNLDPEIDE 113 Query: 177 SQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIK 236 L++ F KI+ D TG SKGY F+ F + D A+ M G +L R I Sbjct: 114 KLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPIT 173 Query: 237 VGPT 240 V Sbjct: 174 VSYA 177 Score = 106 bits (265), Expect = 2e-23, Method: Composition-based stats. Identities = 43/257 (16%), Positives = 93/257 (36%), Gaps = 63/257 (24%) Query: 158 KSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE 217 + + +++VG L V+E L+ELF+ + + + D+VTG +GYGFV+F + ++ Sbjct: 8 ERNQDATVYVGGLDEKVSEPLLWELFL-QAGPVVNTHMPKDRVTGQHQGYGFVEFLSEED 66 Query: 218 QQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFL 277 A+ M + L G+ I+V S Sbjct: 67 ADYAIKIMNMIKLYGKPIRVNKASAH---------------------------------- 92 Query: 278 SNGNNNMGFKRNHMSQFIYP-VQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPF 336 N N+ N + P + ++ + F+ I ++ + + Sbjct: 93 ---NKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGV----ILQTPKIMRDPD-------- 137 Query: 337 GTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWG-----RSAKQTAL 391 K F+ + +++AAI M G + N + +S+ + + + Sbjct: 138 -------TGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSA 190 Query: 392 LQQAMLSNSLQVQQQQP 408 ++ + + + Q +P Sbjct: 191 AERLLAAQNPLSQADRP 207 Score = 54.5 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 46/108 (42%), Gaps = 13/108 (12%) Query: 44 ASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPK 103 A N +L N +++G+LDP D+ + +++ G ++M + Sbjct: 91 AHNKNLDVGAN-IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTG---------- 139 Query: 104 NNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSN 151 N++GY F++F S + A+ M N+ + +++A S Sbjct: 140 NSKGYAFINFASFDASDAAI--EAMNGQYLCNRPITVSYAFKKDSKGE 185 >5MMM-v nrPDB Length = 260 Score = 165 bits (418), Expect = 3e-41, Method: Composition-based stats. Identities = 40/195 (20%), Positives = 78/195 (40%), Gaps = 18/195 (9%) Query: 50 GTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYC 109 G +LY+G++ + + +R I G I +M++ R + Sbjct: 80 GEGARRLYVGNIPRNLNNDELRTIVEEHGAIEI-AEVMYDKYSGRSRR----------FG 128 Query: 110 FVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCS----I 165 FV + ANA+++ + +K+K+N + + + + Sbjct: 129 FVTM-KTVEDANAVIEK-LNDTEIGGRKIKVNITEKPLEGMDIATTQAEDSQFVESPYKV 186 Query: 166 FVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEM 225 ++G+LA VT L + F + AK+ T S G+GFV F++ +E + A+ + Sbjct: 187 YIGNLAKTVTNELLKDFF-SEKGKVLGAKVQRTPGTSKSNGFGFVSFSSEEEVEAAIQAL 245 Query: 226 QGVFLNGRAIKVGPT 240 L G+ I+V Sbjct: 246 NNSVLEGQKIRVNKA 260 Score = 102 bits (253), Expect = 5e-22, Method: Composition-based stats. Identities = 39/224 (17%), Positives = 85/224 (37%), Gaps = 56/224 (25%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++VG++ N+ +L + + + + A++++D+ +G S+ +GFV ++ + Sbjct: 85 RLYVGNIPRNLNNDELRTI-VEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANAVIE 143 Query: 224 EMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNN 283 ++ + GR IKV + + E +D Sbjct: 144 KLNDTEIGGRKIKV------------------NITEKPLEGMD----------------- 168 Query: 284 MGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVK 343 + + SQF+ + V+IG L+ VT + L+ +F G ++ K Sbjct: 169 IATTQAEDSQFVESPYK--------------VYIGNLAKTVTNELLKDFFSEKGKVLGAK 214 Query: 344 I------PVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLS 381 + GFV + EAAI + + ++R++ Sbjct: 215 VQRTPGTSKSNGFGFVSFSSEEEVEAAIQALNNSVLEGQKIRVN 258 Score = 54.1 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 29/77 (37%), Gaps = 6/77 (7%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI------PVGKCCGFVQYVDRLSAEAA 364 +++G + + DELR + G I ++ + GFV A A Sbjct: 82 GARRLYVGNIPRNLNNDELRTIVEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANAV 141 Query: 365 IAGMQGFPIANSRVRLS 381 I + I +++++ Sbjct: 142 IEKLNDTEIGGRKIKVN 158 >5ZWM-4 nrPDB Length = 213 Score = 155 bits (391), Expect = 5e-38, Method: Composition-based stats. Identities = 52/226 (23%), Positives = 86/226 (38%), Gaps = 58/226 (25%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 +++VG++ P +T+ QL+ELFI + K D+V +GY F++F N + Q A+ Sbjct: 10 TVYVGNIDPRITKEQLYELFI-QINPVLRIKYPKDKVLQAYQGYAFIEFYNQGDAQYAIK 68 Query: 224 EMQG-VFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNN 282 M V L R IKV + S G Sbjct: 69 IMNNTVRLYDRLIKVRQVTN-----------------------------------STGTT 93 Query: 283 NMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTI--- 339 N+ N I P+ + +FI L+ + D+L F FG + Sbjct: 94 NLP--SNISKDMILPIAK--------------LFIKNLADSIDSDQLVKIFNKFGKLIRE 137 Query: 340 -VYVKIPVGKC-CGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWG 383 + GK C +V + D A+ AI + +AN+R+ + + Sbjct: 138 PEIFYLSNGKLKCAYVYFEDFEKADLAIKSLNNQLVANNRITVDYA 183 Score = 95.3 bits (235), Expect = 6e-20, Method: Composition-based stats. Identities = 42/221 (19%), Positives = 89/221 (40%), Gaps = 28/221 (12%) Query: 51 TTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCF 110 +GN +Y+G++DP K + +++ + + ++ + L QGY F Sbjct: 6 DSGNTVYVGNIDPRITKEQLYELFIQINPV-LRIKYPKDKVLQA----------YQGYAF 54 Query: 111 VDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSG--NNCSIFVG 168 ++F + A A+ ++ +K+ T+S +N N K +F+ Sbjct: 55 IEFYNQGDAQYAIKIMN-NTVRLYDRLIKVRQVTNSTGTTNLPSNISKDMILPIAKLFIK 113 Query: 169 DLAPNVTESQLFELFINRYASTSHAKIVHDQV-----TGMSKGYGFVKFTNSDEQQLALS 223 +LA ++ QL ++F N++ K++ + G K +V F + ++ LA+ Sbjct: 114 NLADSIDSDQLVKIF-NKFG-----KLIREPEIFYLSNGKLK-CAYVYFEDFEKADLAIK 166 Query: 224 EMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNEN 264 + + I V +++ GN Y L N+ Sbjct: 167 SLNNQLVANNRITVDYAF--KENGKGNAKYGDDVDRLLNKE 205 Score = 52.2 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 38/83 (45%), Gaps = 7/83 (8%) Query: 307 FTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLS 360 ++ + TV++G + +T+++L F ++ +K P K F+++ ++ Sbjct: 3 YSADSGNTVYVGNIDPRITKEQLYELFIQINPVLRIKYPKDKVLQAYQGYAFIEFYNQGD 62 Query: 361 AEAAIAGMQG-FPIANSRVRLSW 382 A+ AI M + + +++ Sbjct: 63 AQYAIKIMNNTVRLYDRLIKVRQ 85 >1FXL-A nrPDB Length = 167 Score = 148 bits (372), Expect = 8e-36, Method: Composition-based stats. Identities = 42/188 (22%), Positives = 84/188 (44%), Gaps = 26/188 (13%) Query: 52 TGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFV 111 + L + L + R ++ S+GE + +++ + + GY FV Sbjct: 1 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIE-SCKLVRDKITG----------QSLGYGFV 49 Query: 112 DFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLA 171 ++ A A+ N + K +K+++A S + S + +++V L Sbjct: 50 NYIDPKDAEKAI--NTLNGLRLQTKTIKVSYARPSSA----------SIRDANLYVSGLP 97 Query: 172 PNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLN 231 +T+ +L +LF ++Y ++I+ DQVTG+S+G GF++F E + A+ + G + Sbjct: 98 KTMTQKELEQLF-SQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPS 156 Query: 232 G--RAIKV 237 G I V Sbjct: 157 GATEPITV 164 Score = 116 bits (289), Expect = 3e-26, Method: Composition-based stats. Identities = 27/111 (24%), Positives = 51/111 (45%), Gaps = 5/111 (4%) Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 ++ V L N+T+ + LF K+V D++TG S GYGFV + + + + A+ Sbjct: 3 TNLIVNYLPQNMTQEEFRSLF-GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI 61 Query: 223 SEMQGVFLNGRAIKVGPTSGQQQHVSGNNDY----NRSSSSLNNENVDSRF 269 + + G+ L + IKV + N Y ++ + E + S++ Sbjct: 62 NTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQY 112 Score = 81.0 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 13/121 (10%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEAA 364 + T + + L +T++E R+ F G I K+ K GFV Y+D AE A Sbjct: 1 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 60 Query: 365 IAGMQGFPIANSRVRLSWGR----SAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYIPS 420 I + G + +++S+ R S + L + Q + +Q Q YG I + Sbjct: 61 INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQ---YGRIIT 117 Query: 421 S 421 S Sbjct: 118 S 118 Score = 60.2 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 51/126 (40%), Gaps = 12/126 (9%) Query: 270 LSKGQSFLSNGNNNMGFKR----NHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVT 325 S G F++ + K N + ++ + + +++ GL +T Sbjct: 42 QSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMT 101 Query: 326 EDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAEAAIAGMQGFPIANSR-- 377 + EL F +G I+ +I V + GF+++ R+ AE AI G+ G + + Sbjct: 102 QKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEP 161 Query: 378 VRLSWG 383 + + + Sbjct: 162 ITVKFA 167 Score = 48.3 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 47/125 (37%), Gaps = 13/125 (10%) Query: 19 DSSPYTNTISSETNNSSTSVLSLQGASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLG 78 D+ NT++ + T +S S+ S+ LY+ L T + + Q+++ G Sbjct: 56 DAEKAINTLNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYG 113 Query: 79 EANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKL 138 I R++ + ++G F+ F A A+ P+ + + Sbjct: 114 RI-ITSRILVDQVTG----------VSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPI 162 Query: 139 KLNWA 143 + +A Sbjct: 163 TVKFA 167 >4EGL-A nrPDB Length = 177 Score = 142 bits (357), Expect = 4e-34, Method: Composition-based stats. Identities = 35/193 (18%), Positives = 87/193 (45%), Gaps = 26/193 (13%) Query: 52 TGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFV 111 L + L ++ +R +++S+GE + +++ + + + GY FV Sbjct: 1 GRTNLIVNYLPQNMTQDELRSLFSSIGEVE-SAKLIRDKVAGH----------SLGYGFV 49 Query: 112 DFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLA 171 ++ ++ A A+ N + +K +K+++A S + + ++++ L Sbjct: 50 NYVTAKDAERAI--NTLNGLRLQSKTIKVSYARPSS----------EVIKDANLYISGLP 97 Query: 172 PNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLN 231 +T+ + ++F +R+ +++++ DQ TG+S+G F++F E + A++ G Sbjct: 98 RTMTQKDVEDMF-SRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPP 156 Query: 232 G--RAIKVGPTSG 242 G I V + Sbjct: 157 GSSEPITVKFAAN 169 Score = 124 bits (311), Expect = 9e-29, Method: Composition-based stats. Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 5/111 (4%) Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 ++ V L N+T+ +L LF + AK++ D+V G S GYGFV + + + + A+ Sbjct: 3 TNLIVNYLPQNMTQDELRSLF-SSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAI 61 Query: 223 SEMQGVFLNGRAIKVGPTSGQQQHVSGNNDY----NRSSSSLNNENVDSRF 269 + + G+ L + IKV + + N Y R+ + + E++ SRF Sbjct: 62 NTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 112 Score = 84.1 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 6/80 (7%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEAA 364 T + + L +T+DELR+ F G + K+ K GFV YV AE A Sbjct: 1 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 60 Query: 365 IAGMQGFPIANSRVRLSWGR 384 I + G + + +++S+ R Sbjct: 61 INTLNGLRLQSKTIKVSYAR 80 Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 42/101 (41%), Gaps = 11/101 (10%) Query: 291 MSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG--- 347 S+ I +PS D ++I GL +T+ ++ F FG I+ ++ V Sbjct: 70 QSKTIKVSYARPSSEVIKD---ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTT 126 Query: 348 ---KCCGFVQYVDRLSAEAAIAGMQGF--PIANSRVRLSWG 383 + F+++ R AE AI G P ++ + + + Sbjct: 127 GLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFA 167 >3NNA-A nrPDB Length = 175 Score = 141 bits (355), Expect = 7e-34, Method: Composition-based stats. Identities = 42/175 (24%), Positives = 81/175 (46%), Gaps = 25/175 (14%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEA-NINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 ++++G + TW + +R+++ G INV L + S++ P ++G CFV F Sbjct: 5 KMFVGQVPRTWSEKDLRELFEQYGAVYEINV-------LRDRSQN---PPQSKGCCFVTF 54 Query: 114 PSSTHAANA--LLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLA 171 + A A L N ++P + +++ A S NN++ + K +F+G ++ Sbjct: 55 YTRKAALEAQNALHNMKVLPGM-HHPIQMKPADS---EKNNAVEDRK------LFIGMIS 104 Query: 172 PNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQ 226 TE+ + +F + + +I+ G+S+G FV FT Q A+ M Sbjct: 105 KKCTENDIRVMF-SSFGQIEECRILRGP-DGLSRGCAFVTFTTRAMAQTAIKAMH 157 Score = 94.9 bits (234), Expect = 8e-20, Method: Composition-based stats. Identities = 30/148 (20%), Positives = 55/148 (37%), Gaps = 30/148 (20%) Query: 252 DYNRSSSSLNNENVDSRF-----------------LSKGQSFLSNGNNNMGFKRNHMSQ- 293 R+ S + + ++ SKG F++ + + Sbjct: 10 QVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHN 69 Query: 294 ------FIYPVQQQPSLNHFTDP-NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPV 346 +P+Q +P+ + + + +FIG +S TE+++R F FG I +I Sbjct: 70 MKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILR 129 Query: 347 G-----KCCGFVQYVDRLSAEAAIAGMQ 369 G + C FV + R A+ AI M Sbjct: 130 GPDGLSRGCAFVTFTTRAMAQTAIKAMH 157 Score = 67.2 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 42/121 (34%), Gaps = 6/121 (4%) Query: 160 GNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTG--MSKGYGFVKFTNSDE 217 + +FVG + +E L ELF +Y + ++ D+ SKG FV F Sbjct: 1 SDAIKMFVGQVPRTWSEKDLRELFE-QYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKA 59 Query: 218 QQLALSEMQGVFL---NGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQ 274 A + + + + I++ P ++ + + S D R + Sbjct: 60 ALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSF 119 Query: 275 S 275 Sbjct: 120 G 120 Score = 56.0 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 28/68 (41%), Gaps = 8/68 (11%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG--------KCCGFVQYVDRLSAEAAI 365 +F+G + +E +LR F+ +G + + + K C FV + R +A A Sbjct: 5 KMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 64 Query: 366 AGMQGFPI 373 + + Sbjct: 65 NALHNMKV 72 >1FNX-H nrPDB Length = 174 Score = 140 bits (352), Expect = 2e-33, Method: Composition-based stats. Identities = 38/197 (19%), Positives = 85/197 (43%), Gaps = 26/197 (13%) Query: 51 TTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCF 110 + L + L ++ + ++ S+G+ + +++ + + GY F Sbjct: 2 DSKTNLIVNYLPQNMTQDEFKSLFGSIGDIE-SCKLVRDKITG----------QSLGYGF 50 Query: 111 VDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDL 170 V++ A A+ N + K +K+++A S + S + +++V L Sbjct: 51 VNYSDPNDADKAI--NTLNGLKLQTKTIKVSYARPSSA----------SIRDANLYVSGL 98 Query: 171 APNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFL 230 +++ ++ +LF ++Y ++I+ DQ TG+S+G GF++F E + A+ + G Sbjct: 99 PKTMSQKEMEQLF-SQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKP 157 Query: 231 NG--RAIKVGPTSGQQQ 245 G I V + Q Sbjct: 158 LGAAEPITVKFANNPSQ 174 Score = 112 bits (280), Expect = 4e-25, Method: Composition-based stats. Identities = 28/111 (25%), Positives = 52/111 (46%), Gaps = 5/111 (4%) Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 ++ V L N+T+ + LF K+V D++TG S GYGFV +++ ++ A+ Sbjct: 5 TNLIVNYLPQNMTQDEFKSLF-GSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAI 63 Query: 223 SEMQGVFLNGRAIKVGPTSGQQQHVSGNNDY----NRSSSSLNNENVDSRF 269 + + G+ L + IKV + N Y ++ S E + S++ Sbjct: 64 NTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQY 114 Score = 75.7 bits (184), Expect = 4e-14, Method: Composition-based stats. Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 13/121 (10%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEAA 364 + T + + L +T+DE ++ F G I K+ K GFV Y D A+ A Sbjct: 3 SKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKA 62 Query: 365 IAGMQGFPIANSRVRLSWGR----SAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYIPS 420 I + G + +++S+ R S + L + Q + +Q Q YG I + Sbjct: 63 INTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQ---YGRIIT 119 Query: 421 S 421 S Sbjct: 120 S 120 Score = 59.9 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 25/131 (19%), Positives = 55/131 (41%), Gaps = 12/131 (9%) Query: 270 LSKGQSFLSNGNNNMGFKR----NHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVT 325 S G F++ + N K N + ++ + + +++ GL ++ Sbjct: 44 QSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMS 103 Query: 326 EDELRAYFQPFGTIVYVKIP------VGKCCGFVQYVDRLSAEAAIAGMQGF-PIANSR- 377 + E+ F +G I+ +I V + GF+++ R+ AE AI G+ G P+ + Sbjct: 104 QKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEP 163 Query: 378 VRLSWGRSAKQ 388 + + + + Q Sbjct: 164 ITVKFANNPSQ 174 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 48/131 (36%), Gaps = 13/131 (9%) Query: 18 NDSSPYTNTISSETNNSSTSVLSLQGASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASL 77 ND+ NT++ + T +S S+ S+ LY+ L T + + Q+++ Sbjct: 57 NDADKAINTLNGLKLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMSQKEMEQLFSQY 114 Query: 78 GEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKK 137 G I R++ + ++G F+ F A A+ P + Sbjct: 115 GRI-ITSRILLDQATG----------VSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEP 163 Query: 138 LKLNWATSSYS 148 + + +A + Sbjct: 164 ITVKFANNPSQ 174 >6D0Y-A nrPDB Length = 176 Score = 135 bits (339), Expect = 5e-32, Method: Composition-based stats. Identities = 32/164 (19%), Positives = 72/164 (43%), Gaps = 6/164 (3%) Query: 112 DFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLA 171 +FP AA+ + G+L + ++L+ + +N +C+++VG+L+ Sbjct: 10 EFPGRLEAADPM-SGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLS 68 Query: 172 PNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLN 231 TE Q++ELF ++ + D++ + G+ FV++ + + + A+ + G L+ Sbjct: 69 FYTTEEQIYELF-SKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLD 127 Query: 232 GRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQS 275 R I+ +G ++ Y R S + + G+ Sbjct: 128 DRIIRTDWDAGFKE----GRQYGRGRSGGQVRDEYRQDYDAGRG 167 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 44/104 (42%), Gaps = 6/104 (5%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEA 363 + T+++G LS TE+++ F G I + + + K FV+Y R AE Sbjct: 57 KKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAEN 116 Query: 364 AIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQ 407 A+ + G + + +R W K+ + ++ + +Q Sbjct: 117 AMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQ 160 Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 37/98 (37%), Gaps = 13/98 (13%) Query: 45 SNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKN 104 L LY+G+L + + ++++ G+ + + K Sbjct: 51 EQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGL-----------DKMKKT 99 Query: 105 NQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNW 142 G+CFV++ S A NA+ + ++ ++ +W Sbjct: 100 ACGFCFVEYYSRADAENAMRY--INGTRLDDRIIRTDW 135 >4LMZ-A nrPDB Length = 180 Score = 132 bits (332), Expect = 3e-31, Method: Composition-based stats. Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 23/174 (13%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFP 114 ++++G + +W + +++++ G N L + S++ P ++G CFV F Sbjct: 10 KMFVGQIPRSWSEKELKELFEPYGAV------YQINVLRDRSQN---PPQSKGCCFVTFY 60 Query: 115 SSTHAANA--LLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAP 172 + A A L N +P + +++ A S +N++ + K +F+G ++ Sbjct: 61 TRKAALEAQNALHNIKTLPGM-HHPIQMKPADS---EKSNAVEDRK------LFIGMVSK 110 Query: 173 NVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQ 226 E+ + +F + + +I+ G+S+G FV F+ Q A+ M Sbjct: 111 KCNENDIRVMF-SPFGQIEECRILRGP-DGLSRGCAFVTFSTRAMAQNAIKAMH 162 Score = 96.5 bits (238), Expect = 3e-20, Method: Composition-based stats. Identities = 29/113 (25%), Positives = 50/113 (44%), Gaps = 13/113 (11%) Query: 270 LSKGQSFLSNGNNNMGFKRNHMSQFI-------YPVQQQPSLNHFTDP-NNTTVFIGGLS 321 SKG F++ + + I +P+Q +P+ + ++ + +FIG +S Sbjct: 50 QSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVS 109 Query: 322 SLVTEDELRAYFQPFGTIVYVKIPVG-----KCCGFVQYVDRLSAEAAIAGMQ 369 E+++R F PFG I +I G + C FV + R A+ AI M Sbjct: 110 KKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMH 162 Score = 66.4 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 44/122 (36%), Gaps = 6/122 (4%) Query: 159 SGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTG--MSKGYGFVKFTNSD 216 + +FVG + + +E +L ELF Y + ++ D+ SKG FV F Sbjct: 5 DPDAIKMFVGQIPRSWSEKELKELFE-PYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRK 63 Query: 217 EQQLALSEMQGVF-LNG--RAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKG 273 A + + + L G I++ P ++ + + S D R + Sbjct: 64 AALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSP 123 Query: 274 QS 275 Sbjct: 124 FG 125 Score = 58.7 bits (140), Expect = 5e-09, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 31/71 (43%), Gaps = 8/71 (11%) Query: 309 DPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG--------KCCGFVQYVDRLS 360 DP+ +F+G + +E EL+ F+P+G + + + K C FV + R + Sbjct: 5 DPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKA 64 Query: 361 AEAAIAGMQGF 371 A A + Sbjct: 65 ALEAQNALHNI 75 >3SXL-A nrPDB Length = 184 Score = 131 bits (330), Expect = 5e-31, Method: Composition-based stats. Identities = 43/182 (23%), Positives = 81/182 (44%), Gaps = 26/182 (14%) Query: 52 TGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFV 111 + L + L + ++ ++G N R+M + + GY FV Sbjct: 13 SNTNLIVNYLPQDMTDRELYALFRAIGPIN-TCRIMRDYKTGY----------SFGYAFV 61 Query: 112 DFPSSTHAANAL-LKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDL 170 DF S + A+ + NG+ + N K+LK+++A +S + +++V +L Sbjct: 62 DFTSEMDSQRAIKVLNGITVRN---KRLKVSYARPG----------GESIKDTNLYVTNL 108 Query: 171 APNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFL 230 +T+ QL +F +Y S I+ D++TG +G FV++ +E Q A+S + V Sbjct: 109 PRTITDDQLDTIF-GKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIP 167 Query: 231 NG 232 G Sbjct: 168 EG 169 Score = 107 bits (267), Expect = 1e-23, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 54/116 (46%), Gaps = 5/116 (4%) Query: 160 GNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQ 219 +N ++ V L ++T+ +L+ LF + +I+ D TG S GY FV FT+ + Q Sbjct: 12 ASNTNLIVNYLPQDMTDRELYALFRA-IGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQ 70 Query: 220 LALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDY----NRSSSSLNNENVDSRFLS 271 A+ + G+ + + +KV + + N Y R+ + + + ++ S Sbjct: 71 RAIKVLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGS 126 Score = 65.6 bits (158), Expect = 5e-11, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 8/90 (8%) Query: 303 SLNHFTDP--NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQ 354 S + DP +NT + + L +T+ EL A F+ G I +I FV Sbjct: 3 SDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVD 62 Query: 355 YVDRLSAEAAIAGMQGFPIANSRVRLSWGR 384 + + ++ AI + G + N R+++S+ R Sbjct: 63 FTSEMDSQRAIKVLNGITVRNKRLKVSYAR 92 >5OO6-B nrPDB Length = 158 Score = 125 bits (313), Expect = 5e-29, Method: Composition-based stats. Identities = 28/153 (18%), Positives = 66/153 (43%), Gaps = 5/153 (3%) Query: 123 LLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFEL 182 + G+L + ++L+ + +N +C+++VG+L+ TE Q++EL Sbjct: 2 AMSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYEL 61 Query: 183 FINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSG 242 F ++ + D++ + G+ FV++ + + + A+ + G L+ R I+ +G Sbjct: 62 F-SKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAG 120 Query: 243 QQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQS 275 ++ Y R S + + G+ Sbjct: 121 FKE----GRQYGRGRSGGQVRDEYRQDYDAGRG 149 Score = 60.2 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 44/104 (42%), Gaps = 6/104 (5%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEA 363 + T+++G LS TE+++ F G I + + + K FV+Y R AE Sbjct: 39 KKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAEN 98 Query: 364 AIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQ 407 A+ + G + + +R W K+ + ++ + +Q Sbjct: 99 AMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQ 142 Score = 47.2 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 37/98 (37%), Gaps = 13/98 (13%) Query: 45 SNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKN 104 L LY+G+L + + ++++ G+ + + K Sbjct: 33 EQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGL-----------DKMKKT 81 Query: 105 NQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNW 142 G+CFV++ S A NA+ + ++ ++ +W Sbjct: 82 ACGFCFVEYYSRADAENAMRY--INGTRLDDRIIRTDW 117 >6QDV-M nrPDB Length = 289 Score = 113 bits (282), Expect = 2e-25, Method: Composition-based stats. Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Query: 293 QFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF 352 + + P L+ D TT+++GGL +TE +LR +F FG I + + + C F Sbjct: 195 KLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAF 254 Query: 353 VQYVDRLSAE-AAIAGMQGFPIANSRVRLSWGRS 385 +Q+ R +AE AA + R+ + WGRS Sbjct: 255 IQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRS 288 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 34/93 (36%), Gaps = 8/93 (8%) Query: 152 NSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVK 211 L+ + +++VG L +TE+ L F ++ +V Q F++ Sbjct: 204 PRLDPPEDKTITTLYVGGLGDTITETDLRNHFY-QFGEIRTITVVQRQQ------CAFIQ 256 Query: 212 FTNSDEQQ-LALSEMQGVFLNGRAIKVGPTSGQ 243 F + A + +NGR + V Q Sbjct: 257 FATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQ 289 Score = 35.6 bits (80), Expect = 0.058, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 28/91 (30%), Gaps = 18/91 (19%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 LY+G L T + +R + GE ++ Q F+ F + Sbjct: 217 LYVGGLGDTITETDLRNHFYQFGEIR-----------------TITVVQRQQCAFIQFAT 259 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNWATSS 146 AA + ++L + W S Sbjct: 260 R-QAAEVAAEKSFNKLIVNGRRLNVKWGRSQ 289 >6ID0-O nrPDB Length = 420 Score = 113 bits (282), Expect = 2e-25, Method: Composition-based stats. Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Query: 293 QFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF 352 + + P L+ D TT+++GGL +TE +LR +F FG I + + + C F Sbjct: 212 KLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAF 271 Query: 353 VQYVDRLSAE-AAIAGMQGFPIANSRVRLSWGRS 385 +Q+ R +AE AA + R+ + WGRS Sbjct: 272 IQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRS 305 Score = 59.5 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 39/115 (33%), Gaps = 8/115 (6%) Query: 152 NSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVK 211 L+ + +++VG L +TE+ L F ++ +V Q F++ Sbjct: 221 PRLDPPEDKTITTLYVGGLGDTITETDLRNHFY-QFGEIRTITVVQRQQ------CAFIQ 273 Query: 212 FTNSDEQQ-LALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENV 265 F + A + +NGR + V Q + S + E V Sbjct: 274 FATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPV 328 Score = 38.3 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 33/110 (30%), Gaps = 18/110 (16%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 LY+G L T + +R + GE ++ Q F+ F + Sbjct: 234 LYVGGLGDTITETDLRNHFYQFGEIR-----------------TITVVQRQQCAFIQFAT 276 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSI 165 AA + ++L + W S + + + + + Sbjct: 277 R-QAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKL 325 >6FF4-1 nrPDB Length = 322 Score = 109 bits (271), Expect = 4e-24, Method: Composition-based stats. Identities = 31/137 (22%), Positives = 58/137 (42%), Gaps = 11/137 (8%) Query: 139 KLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHD 198 +LN ++ + + ++ IF+G L +TE + +F ++Y + +V D Sbjct: 12 ELNEREVQLGVADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVF-SQYGEIVNINLVRD 70 Query: 199 QVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSS 258 + TG SKG+ F+ + + LA+ G+ + GR I+V S Y Sbjct: 71 KKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSN----------YRAPKD 120 Query: 259 SLNNENVDSRFLSKGQS 275 S ++V + KG Sbjct: 121 SEEIDDVTRQLQEKGCG 137 Score = 55.2 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 46/110 (41%), Gaps = 9/110 (8%) Query: 306 HFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCG------FVQYVDRL 359 H ++ +F+GGL +TE ++ F +G IV + + K G F+ Y D+ Sbjct: 29 HSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQR 88 Query: 360 SAEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPG 409 S A+ G I +R+ + + ++ + + Q Q+ G Sbjct: 89 STILAVDNFNGIKIKGRTIRVDHVSNYRAPKDSEEI---DDVTRQLQEKG 135 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 9/102 (8%), Positives = 39/102 (38%), Gaps = 13/102 (12%) Query: 53 GNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVD 112 +++G L + + +++ GE +N+ ++ + ++G+CF+ Sbjct: 35 SAWIFLGGLPYELTEGDIICVFSQYGEI-VNINLVRDKKTGK----------SKGFCFLC 83 Query: 113 FPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSL 154 + A+ + + ++++ ++ + ++ Sbjct: 84 YEDQRSTILAV--DNFNGIKIKGRTIRVDHVSNYRAPKDSEE 123 >5ZWM-X nrPDB Length = 148 Score = 108 bits (269), Expect = 7e-24, Method: Composition-based stats. Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 13/139 (9%) Query: 130 IPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYAS 189 I +K+L+ + S N + +N I++G+L +TE + +F + Y Sbjct: 4 IQQINDKELQSGILSPHQSWHN------EYKDNAYIYIGNLNRELTEGDILTVF-SEYGV 56 Query: 190 TSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPT------SGQ 243 + D+ TG S+G+ ++K+ + LA+ + G + GRA+K+ T S Q Sbjct: 57 PVDVILSRDENTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPKRSLQ 116 Query: 244 QQHVSGNNDYNRSSSSLNN 262 + + + + +R S NN Sbjct: 117 KYYEAVKEELDRDIVSKNN 135 Score = 45.6 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 37/82 (45%), Gaps = 6/82 (7%) Query: 306 HFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRL 359 H +N ++IG L+ +TE ++ F +G V V + + +++Y D+ Sbjct: 24 HNEYKDNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQR 83 Query: 360 SAEAAIAGMQGFPIANSRVRLS 381 S A+ + GF I +++ Sbjct: 84 STILAVDNLNGFKIGGRALKID 105 Score = 35.2 bits (79), Expect = 0.077, Method: Composition-based stats. Identities = 10/88 (11%), Positives = 34/88 (38%), Gaps = 13/88 (14%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 +Y+G+L+ + + +++ G ++V + + +QG+ ++ + Sbjct: 33 IYIGNLNRELTEGDILTVFSEYG-VPVDVILSRDENTG----------ESQGFAYLKYED 81 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNWA 143 A+ + + + LK++ Sbjct: 82 QRSTILAV--DNLNGFKIGGRALKIDHT 107 >2DH7-A nrPDB Length = 105 Score = 105 bits (261), Expect = 5e-23, Method: Composition-based stats. Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Query: 153 SLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKF 212 S + N+ +FVGDL+P +T + F + S A++V D TG SKGYGFV F Sbjct: 6 SGQKKDTSNHFHVFVGDLSPEITTEDIKSAFA-PFGKISDARVVKDMATGKSKGYGFVSF 64 Query: 213 TNSDEQQLALSEMQGVFLNGRAIKVGPTSGQ 243 N + + A+ M G +L GR I+ + + Sbjct: 65 YNKLDAENAIVHMGGQWLGGRQIRTNWATRK 95 Score = 91.4 bits (225), Expect = 9e-19, Method: Composition-based stats. Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 12/91 (13%) Query: 299 QQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGF 352 Q++ + NHF VF+G LS +T +++++ F PFG I ++ K GF Sbjct: 8 QKKDTSNHFH------VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGF 61 Query: 353 VQYVDRLSAEAAIAGMQGFPIANSRVRLSWG 383 V + ++L AE AI M G + ++R +W Sbjct: 62 VSFYNKLDAENAIVHMGGQWLGGRQIRTNWA 92 Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 47/103 (45%), Gaps = 14/103 (13%) Query: 43 GASNVSLGTTGN-QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMG 101 G+S T+ + +++GDL P ++ +A G+ + + R++ + Sbjct: 4 GSSGQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKIS-DARVVKDMATGK------- 55 Query: 102 PKNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWAT 144 ++GY FV F + A NA++ G ++++ NWAT Sbjct: 56 ---SKGYGFVSFYNKLDAENAIVHMG--GQWLGGRQIRTNWAT 93 >5SZW-A nrPDB Length = 101 Score = 104 bits (260), Expect = 7e-23, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%) Query: 153 SLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKF 212 + + ++ V L N+T+ +L LF + AK++ D+V G S GYGFV + Sbjct: 12 AEDCRGDIGRTNLIVNYLPQNMTQDELRSLF-SSIGEVESAKLIRDKVAGHSLGYGFVNY 70 Query: 213 TNSDEQQLALSEMQGVFLNGRAIKVGPTSGQ 243 + + + A++ + G+ L + IKV Sbjct: 71 VTAKDAERAINTLNGLRLQSKTIKVSYARPS 101 Score = 85.7 bits (210), Expect = 5e-17, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 6/82 (7%) Query: 309 DPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAE 362 D T + + L +T+DELR+ F G + K+ K GFV YV AE Sbjct: 18 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 77 Query: 363 AAIAGMQGFPIANSRVRLSWGR 384 AI + G + + +++S+ R Sbjct: 78 RAINTLNGLRLQSKTIKVSYAR 99 Score = 73.7 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 43/95 (45%), Gaps = 13/95 (13%) Query: 52 TGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFV 111 L + L ++ +R +++S+GE + +++ + + + GY FV Sbjct: 20 GRTNLIVNYLPQNMTQDELRSLFSSIGEVE-SAKLIRDKVAGH----------SLGYGFV 68 Query: 112 DFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSS 146 ++ ++ A A+ N + +K +K+++A S Sbjct: 69 NYVTAKDAERAI--NTLNGLRLQSKTIKVSYARPS 101 >1H6K-X nrPDB Length = 98 Score = 104 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Query: 145 SSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMS 204 + +N +C+++VG+L+ TE Q++ELF ++ + D++ + Sbjct: 1 DQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELF-SKSGDIKKIIMGLDKMK-TA 58 Query: 205 KGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQ 244 G+ FV++ + + + A+ + G L+ R I+ +G + Sbjct: 59 CGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFK 98 Score = 59.5 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 36/78 (46%), Gaps = 5/78 (6%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK-----CCGFVQYVDRLSAEAA 364 + T+++G LS TE+++ F G I + + + K FV+Y R AE A Sbjct: 16 KKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKTACGFCFVEYYSRADAENA 75 Query: 365 IAGMQGFPIANSRVRLSW 382 + + G + + +R W Sbjct: 76 MRYINGTRLDDRIIRTDW 93 Score = 46.0 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 38/98 (38%), Gaps = 14/98 (14%) Query: 45 SNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKN 104 L LY+G+L + + ++++ G+ + M + K Sbjct: 10 EQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIK-KIIMGLDKM-----------KT 57 Query: 105 NQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNW 142 G+CFV++ S A NA+ + ++ ++ +W Sbjct: 58 ACGFCFVEYYSRADAENAMRY--INGTRLDDRIIRTDW 93 >1P1T-A nrPDB Length = 104 Score = 102 bits (254), Expect = 3e-22, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 S+FVG++ TE QL ++F + ++V+D+ TG KGYGF ++ + + A+ Sbjct: 10 SVFVGNIPYEATEEQLKDIF-SEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMR 68 Query: 224 EMQGVFLNGRAIKVGPTSGQQQHVSGNND 252 + G +GRA++V + ++ + Sbjct: 69 NLNGREFSGRALRVDNAASEKNKEELKSL 97 Score = 58.7 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 43/97 (44%), Gaps = 6/97 (6%) Query: 305 NHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDR 358 + D + +VF+G + TE++L+ F G +V ++ K GF +Y D+ Sbjct: 1 DPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQ 60 Query: 359 LSAEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQA 395 +A +A+ + G + +R+ S K L+ Sbjct: 61 ETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSL 97 Score = 49.1 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 13/98 (13%), Positives = 43/98 (43%), Gaps = 13/98 (13%) Query: 48 SLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQG 107 ++ + +++G++ + ++ I++ +G ++ R++++ +G Sbjct: 3 AVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPV-VSFRLVYDRETGKP----------KG 51 Query: 108 YCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATS 145 Y F ++ A +A+ + F + L+++ A S Sbjct: 52 YGFCEYQDQETALSAM--RNLNGREFSGRALRVDNAAS 87 >2YTC-A nrPDB Length = 85 Score = 101 bits (251), Expect = 7e-22, Method: Composition-based stats. Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Query: 308 TDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAE-AAIA 366 D TT+++GGL +TE +LR +F FG I + + + C F+Q+ R +AE AA Sbjct: 8 EDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEVAAEK 67 Query: 367 GMQGFPIANSRVRLSWGR 384 + R+ + WGR Sbjct: 68 SFNKLIVNGRRLNVKWGR 85 Score = 53.7 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 34/90 (37%), Gaps = 8/90 (8%) Query: 153 SLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKF 212 S ++ + +++VG L +TE+ L F ++ +V Q F++F Sbjct: 3 SGSSGEDKTITTLYVGGLGDTITETDLRNHFY-QFGEIRTITVVQRQQ------CAFIQF 55 Query: 213 TNSDEQQ-LALSEMQGVFLNGRAIKVGPTS 241 + A + +NGR + V Sbjct: 56 ATRQAAEVAAEKSFNKLIVNGRRLNVKWGR 85 Score = 34.4 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 32/103 (31%), Gaps = 19/103 (18%) Query: 43 GASNVSLGT-TGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMG 101 G+S S T LY+G L T + +R + GE ++ Sbjct: 1 GSSGSSGEDKTITTLYVGGLGDTITETDLRNHFYQFGEIR-----------------TIT 43 Query: 102 PKNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWAT 144 Q F+ F + AA + ++L + W Sbjct: 44 VVQRQQCAFIQFATR-QAAEVAAEKSFNKLIVNGRRLNVKWGR 85 >2SXL-A nrPDB Length = 88 Score = 101 bits (251), Expect = 9e-22, Method: Composition-based stats. Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Query: 160 GNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQ 219 +N ++ V L ++T+ +L+ LF + +I+ D TG S GY FV FT+ + Q Sbjct: 1 ASNTNLIVNYLPQDMTDRELYALFRA-IGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQ 59 Query: 220 LALSEMQGVFLNGRAIKVGPTSGQQQHVS 248 A+ + G+ + + +KV + + Sbjct: 60 RAIKVLNGITVRNKRLKVSYARPGGESIK 88 Score = 65.3 bits (157), Expect = 6e-11, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 6/81 (7%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEA 363 +NT + + L +T+ EL A F+ G I +I FV + + ++ Sbjct: 1 ASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQR 60 Query: 364 AIAGMQGFPIANSRVRLSWGR 384 AI + G + N R+++S+ R Sbjct: 61 AIKVLNGITVRNKRLKVSYAR 81 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 40/98 (40%), Gaps = 15/98 (15%) Query: 52 TGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFV 111 + L + L + ++ ++G N R+M + + GY FV Sbjct: 2 SNTNLIVNYLPQDMTDRELYALFRAIGPIN-TCRIMRDYKTGY----------SYGYAFV 50 Query: 112 DFPSSTHAANAL-LKNGMLIPNFPNKKLKLNWATSSYS 148 DF S + A+ + NG+ + N K+LK+++A Sbjct: 51 DFTSEMDSQRAIKVLNGITVRN---KRLKVSYARPGGE 85 >3HI9-A nrPDB Length = 84 Score = 101 bits (250), Expect = 1e-21, Method: Composition-based stats. Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 1/81 (1%) Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 ++ V L N+T+ +L LF + AK++ D+V G S GYGFV + + + + A+ Sbjct: 5 TNLIVNYLPQNMTQDELRSLF-SSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAI 63 Query: 223 SEMQGVFLNGRAIKVGPTSGQ 243 + + G+ L + IKV Sbjct: 64 NTLNGLRLQSKTIKVSYARPS 84 Score = 84.9 bits (208), Expect = 9e-17, Method: Composition-based stats. Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 6/81 (7%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEA 363 P T + + L +T+DELR+ F G + K+ K GFV YV AE Sbjct: 2 PGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 61 Query: 364 AIAGMQGFPIANSRVRLSWGR 384 AI + G + + +++S+ R Sbjct: 62 AINTLNGLRLQSKTIKVSYAR 82 Score = 73.7 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 44/97 (45%), Gaps = 13/97 (13%) Query: 50 GTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYC 109 G L + L ++ +R +++S+GE + +++ + + + GY Sbjct: 1 GPGRTNLIVNYLPQNMTQDELRSLFSSIGEVE-SAKLIRDKVAGH----------SLGYG 49 Query: 110 FVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSS 146 FV++ ++ A A+ N + +K +K+++A S Sbjct: 50 FVNYVTAKDAERAI--NTLNGLRLQSKTIKVSYARPS 84 >4FXV-A nrPDB Length = 99 Score = 100 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 1/83 (1%) Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 ++ V L N+T+ +L LF + AK++ D+V G S GYGFV + + + + Sbjct: 18 QGTNLIVNYLPQNMTQDELRSLF-SSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 76 Query: 221 ALSEMQGVFLNGRAIKVGPTSGQ 243 A++ + G+ L + IKV Sbjct: 77 AINTLNGLRLQSKTIKVSYARPS 99 Score = 82.6 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 6/80 (7%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEAA 364 T + + L +T+DELR+ F G + K+ K GFV YV AE A Sbjct: 18 QGTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77 Query: 365 IAGMQGFPIANSRVRLSWGR 384 I + G + + +++S+ R Sbjct: 78 INTLNGLRLQSKTIKVSYAR 97 Score = 72.6 bits (176), Expect = 4e-13, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 44/94 (46%), Gaps = 13/94 (13%) Query: 53 GNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVD 112 G L + L ++ +R +++S+GE + +++ + + + GY FV+ Sbjct: 19 GTNLIVNYLPQNMTQDELRSLFSSIGEVE-SAKLIRDKVAGH----------SLGYGFVN 67 Query: 113 FPSSTHAANALLKNGMLIPNFPNKKLKLNWATSS 146 + ++ A A+ N + +K +K+++A S Sbjct: 68 YVTAKDAERAI--NTLNGLRLQSKTIKVSYARPS 99 >1D8Z-A nrPDB Length = 89 Score = 99.5 bits (246), Expect = 3e-21, Method: Composition-based stats. Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 1/82 (1%) Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 ++ V L N+T+ + LF K+V D++TG S GYGFV +++ ++ A+ Sbjct: 5 TNLIVNYLPQNMTQDEFKSLF-GSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAI 63 Query: 223 SEMQGVFLNGRAIKVGPTSGQQ 244 + + G+ L + IKV Sbjct: 64 NTLNGLKLQTKTIKVSYARPSS 85 Score = 74.1 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 6/85 (7%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEAA 364 + T + + L +T+DE ++ F G I K+ K GFV Y D A+ A Sbjct: 3 SKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKA 62 Query: 365 IAGMQGFPIANSRVRLSWGRSAKQT 389 I + G + +++S+ R + + Sbjct: 63 INTLNGLKLQTKTIKVSYARPSSAS 87 Score = 64.9 bits (156), Expect = 8e-11, Method: Composition-based stats. Identities = 15/98 (15%), Positives = 39/98 (39%), Gaps = 13/98 (13%) Query: 51 TTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCF 110 + L + L ++ + ++ S+G+ + +++ + + GY F Sbjct: 2 DSKTNLIVNYLPQNMTQDEFKSLFGSIGDIE-SCKLVRDKITG----------QSLGYGF 50 Query: 111 VDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYS 148 V++ A A+ N + K +K+++A S + Sbjct: 51 VNYSDPNDADKAI--NTLNGLKLQTKTIKVSYARPSSA 86 >6GD1-A nrPDB Length = 206 Score = 98.4 bits (243), Expect = 7e-21, Method: Composition-based stats. Identities = 24/107 (22%), Positives = 49/107 (45%), Gaps = 1/107 (0%) Query: 139 KLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHD 198 K+ + N S IF+ +L + E L+++F + + ++ K++ D Sbjct: 100 KVGALSKGQLKEFLDANLAGSAMGWCIFIYNLGQDADEGILWQMF-GPFGAVTNVKVIRD 158 Query: 199 QVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQ 245 T KG+GFV TN +E +A++ + G L + ++V + + Sbjct: 159 FNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSH 205 Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 6/74 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAEAAIAGM 368 +FI L E L F PFG + VK+ K GFV + A AIA + Sbjct: 126 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 185 Query: 369 QGFPIANSRVRLSW 382 G+ + + +++S+ Sbjct: 186 NGYRLGDKILQVSF 199 Score = 37.9 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 39/92 (42%), Gaps = 13/92 (14%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 +++ +L D+ + Q++ G NV+++ + N +G+ FV + Sbjct: 126 IFIYNLGQDADEGILWQMFGPFGAVT-NVKVIRDFNTNK----------CKGFGFVTMTN 174 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNWATSSY 147 AA A+ + +K L++++ T+ Sbjct: 175 YEEAAMAIAS--LNGYRLGDKILQVSFKTNKS 204 >6QX9-R nrPDB Length = 480 Score = 97.6 bits (241), Expect = 1e-20, Method: Composition-based stats. Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 9/100 (9%) Query: 141 NWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQV 200 +W S + ++ IF GDL V + L F +R+ S AK++ D+ Sbjct: 367 SWEDPSLLEWD--------ADDFRIFCGDLGNEVNDDILARAF-SRFPSFLKAKVIRDKR 417 Query: 201 TGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPT 240 TG +KGYGFV F + + A+ EM G ++ R IK+ + Sbjct: 418 TGKTKGYGFVSFKDPSDYVRAMREMNGKYVGSRPIKLRKS 457 Score = 51.4 bits (121), Expect = 9e-07, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 33/78 (42%), Gaps = 6/78 (7%) Query: 309 DPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAE 362 D ++ +F G L + V +D L F F + + K+ K GFV + D Sbjct: 377 DADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYV 436 Query: 363 AAIAGMQGFPIANSRVRL 380 A+ M G + + ++L Sbjct: 437 RAMREMNGKYVGSRPIKL 454 Score = 38.3 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 13/98 (13%), Positives = 36/98 (36%), Gaps = 13/98 (13%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFP 114 +++ GDL + + + + ++ + +++ + +GY FV F Sbjct: 382 RIFCGDLGNEVNDDILARAFSRFPSF-LKAKVIRDKRTGK----------TKGYGFVSFK 430 Query: 115 SSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNN 152 + A+ + M ++ +KL + N + Sbjct: 431 DPSDYVRAMRE--MNGKYVGSRPIKLRKSMWKDRNLDV 466 >5EV3-A nrPDB Length = 201 Score = 96.1 bits (237), Expect = 3e-20, Method: Composition-based stats. Identities = 34/201 (16%), Positives = 78/201 (38%), Gaps = 24/201 (11%) Query: 53 GNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVD 112 +LY+G++ + + + N +R+ ++ ++ + F++ Sbjct: 8 ARRLYVGNIPFGITEEAMMDFF------NAQMRLGGLTQAPGNPVLAVQINQDKNFAFLE 61 Query: 113 FPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSG------------ 160 F S A+ +G++ F + LK+ ++ S Sbjct: 62 FRSVDETTQAMAFDGII---FQGQSLKIR--RPHDYQPLPGMSENPSVYVPGVVSTVVPD 116 Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 + +F+G L + + Q+ EL + + +V D TG+SKGY F ++ + + Sbjct: 117 SAHKLFIGGLPNYLNDDQVKELLTS-FGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQ 175 Query: 221 ALSEMQGVFLNGRAIKVGPTS 241 A++ + G+ L + + V S Sbjct: 176 AIAGLNGMQLGDKKLLVQRAS 196 Score = 69.9 bits (169), Expect = 3e-12, Method: Composition-based stats. Identities = 36/233 (15%), Positives = 76/233 (32%), Gaps = 66/233 (28%) Query: 164 SIFVGDLAPNVTESQLFELFINRY----------ASTSHAKIVHDQVTGMSKGYGFVKFT 213 ++VG++ +TE + + F + +I D+ + F++F Sbjct: 10 RLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKN------FAFLEFR 63 Query: 214 NSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKG 273 + DE A+ G+ G+++K+ R + Sbjct: 64 SVDETTQAM-AFDGIIFQGQSLKIR----------------RPHDYQPLPGMSENPSVYV 106 Query: 274 QSFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYF 333 +S + K +FIGGL + + +D+++ Sbjct: 107 PGVVSTVVPDSAHK---------------------------LFIGGLPNYLNDDQVKELL 139 Query: 334 QPFGTIVYVKIPVG------KCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRL 380 FG + + K F +YVD + AIAG+ G + + ++ + Sbjct: 140 TSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLV 192 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 19/133 (14%), Positives = 43/133 (32%), Gaps = 32/133 (24%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQ-----------PFGTIVYVKIPVGKCCGFVQYVDR 358 +++G + +TE+ + +F P ++ V+I K F+++ Sbjct: 6 RQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSV 65 Query: 359 LSAEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYI 418 A+ G +++ Q PG+ + Y+ Sbjct: 66 DETTQAM-AFDGIIFQGQSLKIRRPHD------------------YQPLPGMSENPSVYV 106 Query: 419 PSSTCEAPVLPDN 431 P + V+PD+ Sbjct: 107 PGVV--STVVPDS 117 >1SXL-A nrPDB Length = 97 Score = 94.9 bits (234), Expect = 7e-20, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 11/93 (11%) Query: 140 LNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQ 199 +++A +S + +++V +L +T+ QL +F +Y S I+ D+ Sbjct: 1 MSYARPG----------GESIKDTNLYVTNLPRTITDDQLDTIF-GKYGSIVQKNILRDK 49 Query: 200 VTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNG 232 +TG +G FV++ +E Q A+S + V G Sbjct: 50 LTGRPRGVAFVRYNKREEAQEAISALNNVIPEG 82 Score = 57.9 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 32/79 (40%), Gaps = 6/79 (7%) Query: 300 QQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFV 353 + +T +++ L +T+D+L F +G+IV I K FV Sbjct: 1 MSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFV 60 Query: 354 QYVDRLSAEAAIAGMQGFP 372 +Y R A+ AI+ + Sbjct: 61 RYNKREEAQEAISALNNVI 79 Score = 48.3 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 30/91 (32%), Gaps = 11/91 (12%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 LY+ +L T + + I+ G + ++ + G FV + Sbjct: 16 LYVTNLPRTITDDQLDTIFGKYGSI-VQKNILRDKLTGRPR----------GVAFVRYNK 64 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNWATSS 146 A A+ +IP ++ L + A Sbjct: 65 REEAQEAISALNNVIPEGGSQPLSVRLAEEH 95 >2YWK-A nrPDB Length = 95 Score = 94.1 bits (232), Expect = 1e-19, Method: Composition-based stats. Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 7/100 (7%) Query: 144 TSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGM 203 +S S + + ++FVG+L V E L+ELF+ + + I D+ G Sbjct: 2 SSGSSGMFPAQEEA----DRTVFVGNLEARVREEILYELFL-QAGPLTKVTICKDR-EGK 55 Query: 204 SKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKV-GPTSG 242 K +GFV F + + A++ + G+ L GR I V GP+SG Sbjct: 56 PKSFGFVCFKHPESVSYAIALLNGIRLYGRPINVSGPSSG 95 Score = 56.0 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 5/81 (6%) Query: 306 HFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG-----KCCGFVQYVDRLS 360 + + TVF+G L + V E+ L F G + V I K GFV + S Sbjct: 10 PAQEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCFKHPES 69 Query: 361 AEAAIAGMQGFPIANSRVRLS 381 AIA + G + + +S Sbjct: 70 VSYAIALLNGIRLYGRPINVS 90 >5MDU-A nrPDB Length = 157 Score = 92.6 bits (228), Expect = 4e-19, Method: Composition-based stats. Identities = 23/71 (32%), Positives = 40/71 (56%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFP 372 T+F+GG++ V E LR+ F+ FG++ + + GF++ R +AE A M+ P Sbjct: 23 RTLFLGGITRSVREPVLRSMFERFGSVQSLILNHNYRHGFLKMFRRDAAEKAQVAMENVP 82 Query: 373 IANSRVRLSWG 383 A++ +R WG Sbjct: 83 FADTTIRTKWG 93 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 32/79 (40%), Gaps = 7/79 (8%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++F+G + +V E L +F R+ S + H+ +GF+K D + A Sbjct: 24 TLFLGGITRSVREPVLRSMFE-RFGSVQSLILNHNYR------HGFLKMFRRDAAEKAQV 76 Query: 224 EMQGVFLNGRAIKVGPTSG 242 M+ V I+ G Sbjct: 77 AMENVPFADTTIRTKWGVG 95 Score = 36.4 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 13/82 (15%), Positives = 29/82 (35%), Gaps = 2/82 (2%) Query: 61 LDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAA 120 + P K R ++ ++ ++ + GS S+ +N + F+ A Sbjct: 13 IPPDSIKVYSRTLFLGGITRSVREPVLRSMFERFGSVQSLILNHNYRHGFLKMFRRDAAE 72 Query: 121 NALLKNGMLIPNFPNKKLKLNW 142 A + M F + ++ W Sbjct: 73 KAQV--AMENVPFADTTIRTKW 92 >5ZWN-Q nrPDB Length = 300 Score = 91.4 bits (225), Expect = 8e-19, Method: Composition-based stats. Identities = 34/149 (22%), Positives = 60/149 (40%), Gaps = 8/149 (5%) Query: 144 TSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGM 203 N N + + +IF+G L ++ E +L + F+ ++ +IV D++T Sbjct: 88 RLQNWNPNVDPHIKDTDPYRTIFIGRLPYDLDEIELQKYFV-KFGEIEKIRIVKDKITQK 146 Query: 204 SKGYGFVKFTNSDEQQLALSEM---QGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSL 260 SKGY F+ F + ++A E+ +G+ + R V G+ Sbjct: 147 SKGYAFIVFKDPISSKMAFKEIGVHRGIQIKDRICIVDIERGRTVKYFKPRRLGGGLGGR 206 Query: 261 NNENVDSRFLSKGQSFLSNGNNNMGFKRN 289 N DSR + F S +N +RN Sbjct: 207 GYSNRDSRLPGR---FASASTSN-PAERN 231 Score = 49.1 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 34/138 (24%), Positives = 52/138 (37%), Gaps = 14/138 (10%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAEAAIA 366 T+FIG L + E EL+ YF FG I ++I K F+ + D +S++ A Sbjct: 107 RTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFK 166 Query: 367 GMQ---GFPIANS--RVRLSWGRSAKQTALLQQAMLSNSLQVQQQQ---PGLQQPNYGYI 418 + G I + V + GR+ K + + PG Sbjct: 167 EIGVHRGIQIKDRICIVDIERGRTVKYFKPRRLGGGLGGRGYSNRDSRLPGRFASASTSN 226 Query: 419 PSSTCEAPVLPDNNVSST 436 P+ AP LP SS+ Sbjct: 227 PAERNYAPRLPRRETSSS 244 Score = 36.4 bits (82), Expect = 0.034, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 30/75 (40%), Gaps = 11/75 (14%) Query: 54 NQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 +++G L D+ +++ + GE +R++ + ++GY F+ F Sbjct: 107 RTIFIGRLPYDLDEIELQKYFVKFGEIE-KIRIVKDKITQK----------SKGYAFIVF 155 Query: 114 PSSTHAANALLKNGM 128 + A + G+ Sbjct: 156 KDPISSKMAFKEIGV 170 >6G90-B nrPDB Length = 300 Score = 91.1 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 34/147 (23%), Positives = 60/147 (40%), Gaps = 8/147 (5%) Query: 146 SYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSK 205 N N + + +IF+G L ++ E +L + F+ ++ +IV D++T SK Sbjct: 90 QNWNPNVDPHIKDTDPYRTIFIGRLPYDLDEIELQKYFV-KFGEIEKIRIVKDKITQKSK 148 Query: 206 GYGFVKFTNSDEQQLALSEM---QGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNN 262 GY F+ F + ++A E+ +G+ + R V G+ Sbjct: 149 GYAFIVFKDPISSKMAFKEIGVHRGIQIKDRICIVDIERGRTVKYFKPRRLGGGLGGRGY 208 Query: 263 ENVDSRFLSKGQSFLSNGNNNMGFKRN 289 N DSR + F S +N +RN Sbjct: 209 SNRDSRLPGR---FASASTSN-PAERN 231 Score = 49.1 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 34/138 (24%), Positives = 52/138 (37%), Gaps = 14/138 (10%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAEAAIA 366 T+FIG L + E EL+ YF FG I ++I K F+ + D +S++ A Sbjct: 107 RTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFK 166 Query: 367 GMQ---GFPIANS--RVRLSWGRSAKQTALLQQAMLSNSLQVQQQQ---PGLQQPNYGYI 418 + G I + V + GR+ K + + PG Sbjct: 167 EIGVHRGIQIKDRICIVDIERGRTVKYFKPRRLGGGLGGRGYSNRDSRLPGRFASASTSN 226 Query: 419 PSSTCEAPVLPDNNVSST 436 P+ AP LP SS+ Sbjct: 227 PAERNYAPRLPRRETSSS 244 Score = 36.4 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 30/75 (40%), Gaps = 11/75 (14%) Query: 54 NQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 +++G L D+ +++ + GE +R++ + ++GY F+ F Sbjct: 107 RTIFIGRLPYDLDEIELQKYFVKFGEIE-KIRIVKDKITQK----------SKGYAFIVF 155 Query: 114 PSSTHAANALLKNGM 128 + A + G+ Sbjct: 156 KDPISSKMAFKEIGV 170 >1D9A-A nrPDB Length = 85 Score = 86.1 bits (211), Expect = 3e-17, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 3/86 (3%) Query: 162 NCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLA 221 + +++V L +++ ++ +LF ++Y ++I+ DQ TG+S+G GF++F E + A Sbjct: 1 DANLYVSGLPKTMSQKEMEQLF-SQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEA 59 Query: 222 LSEMQGVFLNG--RAIKVGPTSGQQQ 245 + + G G I V + Q Sbjct: 60 IKGLNGQKPLGAAEPITVKFANNPSQ 85 Score = 55.2 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 42/85 (49%), Gaps = 8/85 (9%) Query: 312 NTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP------VGKCCGFVQYVDRLSAEAAI 365 + +++ GL +++ E+ F +G I+ +I V + GF+++ R+ AE AI Sbjct: 1 DANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAI 60 Query: 366 AGMQGF-PIANSR-VRLSWGRSAKQ 388 G+ G P+ + + + + + Q Sbjct: 61 KGLNGQKPLGAAEPITVKFANNPSQ 85 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 33/95 (34%), Gaps = 11/95 (11%) Query: 54 NQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 LY+ L T + + Q+++ G I R++ + ++G F+ F Sbjct: 2 ANLYVSGLPKTMSQKEMEQLFSQYGRI-ITSRILLDQATG----------VSRGVGFIRF 50 Query: 114 PSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYS 148 A A+ P + + + +A + Sbjct: 51 DKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQ 85 >2CJK-A nrPDB Length = 167 Score = 85.7 bits (210), Expect = 4e-17, Method: Composition-based stats. Identities = 31/191 (16%), Positives = 75/191 (39%), Gaps = 27/191 (14%) Query: 53 GNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVD 112 ++++G L+ ++ +R+ + G ++++M + ++G+ F+ Sbjct: 3 SCKMFIGGLNWDTTEDNLREYFGKYGTVT-DLKIMKDPATGR----------SRGFGFLS 51 Query: 113 FPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAP 172 F + + +L K + A IFVG + P Sbjct: 52 FEKPSSVDEVVKTQHILD----GKVIDPKRAIPRDEQDKTG----------KIFVGGIGP 97 Query: 173 NVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNG 232 +V + E F +++ + A+++ D+ TG S+G+GFV + ++D + + Sbjct: 98 DVRPKEFEEFF-SQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADAVDRVCQN-KFIDFKD 155 Query: 233 RAIKVGPTSGQ 243 R I++ + Sbjct: 156 RKIEIKRAEPR 166 Score = 84.1 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 25/113 (22%), Positives = 43/113 (38%), Gaps = 3/113 (2%) Query: 160 GNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQ 219 +C +F+G L + TE L E F +Y + + KI+ D TG S+G+GF+ F Sbjct: 1 KESCKMFIGGLNWDTTEDNLREYF-GKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVD 59 Query: 220 LALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSK 272 + L+G+ I + + + F S+ Sbjct: 60 EVVKTQH--ILDGKVIDPKRAIPRDEQDKTGKIFVGGIGPDVRPKEFEEFFSQ 110 Score = 48.3 bits (113), Expect = 9e-06, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 9/77 (11%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI------PVGKCCGFVQYVDRLSAEA 363 + +FIGGL+ TED LR YF +GT+ +KI + GF+ + S + Sbjct: 1 KESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDE 60 Query: 364 AIAG---MQGFPIANSR 377 + + G I R Sbjct: 61 VVKTQHILDGKVIDPKR 77 >2RT3-A nrPDB Length = 97 Score = 84.9 bits (208), Expect = 8e-17, Method: Composition-based stats. Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 5/75 (6%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFP 372 VF+G L + +TEDE+R +PFG I +KI + FV + L+ AAI +Q P Sbjct: 19 RNVFLGNLPNGITEDEIREDLEPFGPIDQIKIVTERNIAFVHF---LNIAAAIKAVQELP 75 Query: 373 IAN--SRVRLSWGRS 385 + S+ R+ +GR Sbjct: 76 LNPKWSKRRIYYGRD 90 Score = 51.8 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 7/80 (8%) Query: 146 SYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSK 205 S SNS+ L +SG ++F+G+L +TE ++ E + + KIV ++ Sbjct: 2 SASNSSVLLAVQQSGACRNVFLGNLPNGITEDEIRED-LEPFGPIDQIKIVTERN----- 55 Query: 206 GYGFVKFTNSDEQQLALSEM 225 FV F N A+ E+ Sbjct: 56 -IAFVHFLNIAAAIKAVQEL 74 >4PKD-B nrPDB Length = 279 Score = 83.4 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 37/250 (14%), Positives = 79/250 (31%), Gaps = 24/250 (9%) Query: 158 KSGNNCSIFVGDLAPNVTESQL----FELFINRYASTSHAKIVHDQVTGMSKGYGFVKFT 213 ++ N +I++ +L + + +L + +F +++ + +G FV F Sbjct: 4 ETRPNHTIYINNLNEKIKKDELKKSLYAIF-SQFGQILDILVSRSL---KMRGQAFVIFK 59 Query: 214 NSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVS------GNNDYNRSSSSLNNENVDS 267 AL MQG + +++ ++ D R + + Sbjct: 60 EVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRGSGSGSGSG 119 Query: 268 RFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNT--TVFIGGLSSLVT 325 + ++ N + T+F+ ++ T Sbjct: 120 SGSGAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTT 179 Query: 326 EDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEAAIAGMQGFPIANSRVR 379 E +LR F+ +G I + + K F++Y +A G I RV Sbjct: 180 ESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVL 239 Query: 380 LS--WGRSAK 387 + GR+ K Sbjct: 240 VDVERGRTVK 249 Score = 60.6 bits (145), Expect = 1e-09, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 7/86 (8%) Query: 307 FTDPNNTTVFIGGLSSLVTEDELRA----YFQPFGTIVYVKIPVG---KCCGFVQYVDRL 359 N T++I L+ + +DEL+ F FG I+ + + + FV + + Sbjct: 3 PETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVS 62 Query: 360 SAEAAIAGMQGFPIANSRVRLSWGRS 385 SA A+ MQGFP + +R+ + ++ Sbjct: 63 SATNALRSMQGFPFYDKPMRIQYAKT 88 >4CQ1-A nrPDB Length = 196 Score = 81.8 bits (200), Expect = 6e-16, Method: Composition-based stats. Identities = 44/229 (19%), Positives = 86/229 (37%), Gaps = 41/229 (17%) Query: 162 NCSIFVGDLAPNV-TESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 N + V +L + T LF LF Y KI++++ ++ + ++ QL Sbjct: 2 NTVLLVSNLNEEMVTPQSLFTLF-GVYGDVQRVKILYNKKDS-----ALIQMADGNQSQL 55 Query: 221 ALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNG 280 A++ + G + G+ I+V + L E +D + L+K Sbjct: 56 AMNHLNGQKMYGKIIRV-------------TLSKHQTVQLPREGLDDQGLTKDFG----- 97 Query: 281 NNNMGFKRNHMSQFIYPVQQQPSLNHFTD--PNNTTVFIGGLSSLVTEDELRAYFQPF-G 337 N R ++P +F + P + T+ + + V E++LR F G Sbjct: 98 --NSPLHR----------FKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGG 145 Query: 338 TIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIA-NSRVRLSWGRS 385 T+ K +Q A A+ + + + N +R+S+ +S Sbjct: 146 TVKAFKFFQDHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKS 194 Score = 31.4 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 33/79 (41%), Gaps = 9/79 (11%) Query: 1 MSYKQTTYYPSRGNLVRNDSSPYTNTISSETNNSSTSVLSLQGASN-VSLGTTGNQLYMG 59 +S QT P G +D ++ + NS G+ N ++ L++ Sbjct: 74 LSKHQTVQLPREG---LDDQG-----LTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLS 125 Query: 60 DLDPTWDKNTVRQIWASLG 78 ++ P+ + +R ++A+ G Sbjct: 126 NIPPSVAEEDLRTLFANTG 144 >6AH0-p nrPDB Length = 225 Score = 81.8 bits (200), Expect = 7e-16, Method: Composition-based stats. Identities = 38/229 (16%), Positives = 77/229 (33%), Gaps = 16/229 (6%) Query: 162 NCSIFVGDLAPNVTESQL----FELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE 217 N +I++ ++ + + +L + LF +++ + T +G FV F Sbjct: 6 NHTIYINNMNDKIKKEELKRSLYALF-SQFGHVVDIVALK---TMKMRGQAFVIFKELGS 61 Query: 218 QQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFL 277 AL ++QG G+ +++ +S + + Sbjct: 62 STNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATTTN 121 Query: 278 SNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFG 337 N P+ P N +F+ L E L F F Sbjct: 122 KKPGQGTPNSANTQGN------STPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFP 175 Query: 338 TIVYVKIPVGKC-CGFVQYVDRLSAEAAIAGMQGFPIANSR-VRLSWGR 384 V++ G+ FV++ + A AA +QGF I S +++++ + Sbjct: 176 GFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAK 224 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 22/141 (15%) Query: 312 NTTVFIGGLSSLVTEDELR----AYFQPFG---TIVYVKIPVGKCCGFVQYVDRLSAEAA 364 N T++I ++ + ++EL+ A F FG IV +K + FV + + S+ A Sbjct: 6 NHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNA 65 Query: 365 IAGMQGFPIANSRVRLSWGR------SAKQTALLQQAM---------LSNSLQVQQQQPG 409 + +QGFP +R+ + + S + + + + ++PG Sbjct: 66 LRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATTTNKKPG 125 Query: 410 LQQPNYGYIPSSTCEAPVLPD 430 PN ++ P +PD Sbjct: 126 QGTPNSANTQGNSTPNPQVPD 146 >5MQF-o nrPDB Length = 301 Score = 81.4 bits (199), Expect = 8e-16, Method: Composition-based stats. Identities = 37/189 (19%), Positives = 64/189 (33%), Gaps = 13/189 (6%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 ++VG LA V + L FI + + +I D T +G+ FV+F +++ A+ Sbjct: 8 LYVGGLAEEVDDKVLHAAFI-PFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDN 66 Query: 225 MQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNM 284 M L GR I+V + +R S + + +F K + Sbjct: 67 MNESELFGRTIRVNLAKPMR----IKEGSSRPVWSDD--DWLKKFSGKTLEENKEEEGSE 120 Query: 285 GFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPF-GTIVYVK 343 K P+ ++ N + IG + + LR+ P Sbjct: 121 PPKAETQEG--EPIAKKARSNPQVYMDIK---IGNKPAGRIQMLLRSDVVPMTAENFRCL 175 Query: 344 IPVGKCCGF 352 K GF Sbjct: 176 CTHEKGFGF 184 Score = 63.7 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 6/83 (7%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP------VGKCCGFVQYVDRLSAEAA 364 +++GGL+ V + L A F PFG I ++IP + FV++ A AA Sbjct: 4 TKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAA 63 Query: 365 IAGMQGFPIANSRVRLSWGRSAK 387 I M + +R++ + + Sbjct: 64 IDNMNESELFGRTIRVNLAKPMR 86 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 40/98 (40%), Gaps = 15/98 (15%) Query: 49 LGTTGNQLYMGDLDPTWDKNTVRQIWASLGEA-NINVRMMWNNTLNNGSRSSMGPKNNQG 107 + TT LY+G L D + + G+ +I + + + + ++G Sbjct: 1 MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYET------------EKHRG 48 Query: 108 YCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATS 145 + FV+F + AA A+ + M + +++N A Sbjct: 49 FAFVEFELAEDAAAAI--DNMNESELFGRTIRVNLAKP 84 >5EN1-A nrPDB Length = 184 Score = 79.5 bits (194), Expect = 4e-15, Method: Composition-based stats. Identities = 35/192 (18%), Positives = 73/192 (38%), Gaps = 20/192 (10%) Query: 54 NQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 +L++G L + ++R + G+ V +M + K ++G+ FV F Sbjct: 10 RKLFIGGLSFETTEESLRNYYEQWGKLTDCV-VMRD----------PASKRSRGFGFVTF 58 Query: 114 PSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPN 173 S A+ + + ++ A + + + +FVG + + Sbjct: 59 SSMAEVDAAMAAR---PHSIDGRVVEPKRAVAREESGKPGAHVTVKK----LFVGGIKED 111 Query: 174 VTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGR 233 E L + F Y +I+ D+ +G +G+GFV F + D + + +NG Sbjct: 112 TEEHHLRDYFE-EYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDK-IVLQKYHTINGH 169 Query: 234 AIKVGPTSGQQQ 245 +V +Q+ Sbjct: 170 NAEVRKALSRQE 181 Score = 66.0 bits (159), Expect = 3e-11, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 39/93 (41%), Gaps = 5/93 (5%) Query: 155 NNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTN 214 + +F+G L+ TE L + ++ + ++ D + S+G+GFV F++ Sbjct: 2 KKREKEQFRKLFIGGLSFETTEESLRNYYE-QWGKLTDCVVMRDPASKRSRGFGFVTFSS 60 Query: 215 SDEQQLALSE----MQGVFLNGRAIKVGPTSGQ 243 E A++ + G + + SG+ Sbjct: 61 MAEVDAAMAARPHSIDGRVVEPKRAVAREESGK 93 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 6/68 (8%) Query: 306 HFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRL 359 +FIGGLS TE+ LR Y++ +G + + + GFV + Sbjct: 3 KREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMA 62 Query: 360 SAEAAIAG 367 +AA+A Sbjct: 63 EVDAAMAA 70 Score = 46.4 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 50/146 (34%), Gaps = 10/146 (6%) Query: 228 VFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFK 287 +F+ G + + S + + + F S ++ + M + Sbjct: 12 LFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAAR 71 Query: 288 -RNHMSQFIYP---VQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVK 343 + + + P V ++ S +F+GG+ E LR YF+ +G I ++ Sbjct: 72 PHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIE 131 Query: 344 IPVG------KCCGFVQYVDRLSAEA 363 I + GFV + D + Sbjct: 132 IITDRQSGKKRGFGFVTFDDHDPVDK 157 Score = 38.7 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 11/92 (11%), Positives = 31/92 (33%), Gaps = 14/92 (15%) Query: 52 TGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFV 111 T +L++G + +++ +R + G+ + + ++ + G+ FV Sbjct: 99 TVKKLFVGGIKEDTEEHHLRDYFEEYGKID-TIEIITDRQSGKKR----------GFGFV 147 Query: 112 DFPSSTHAANALLKNGMLIPNFPNKKLKLNWA 143 F +L+ ++ A Sbjct: 148 TFDDHDPVDKIVLQK---YHTINGHNAEVRKA 176 >2XS5-A nrPDB Length = 87 Score = 79.1 bits (193), Expect = 4e-15, Method: Composition-based stats. Identities = 28/81 (34%), Positives = 46/81 (56%), Gaps = 4/81 (4%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++FVG + + E+++ F RY S KI+ D+ TG+SKGYGFV F N + Q + Sbjct: 11 TVFVGGIDVRMDETEIRSFFA-RYGSVKEVKIITDR-TGVSKGYGFVSFYNDVDVQKIVE 68 Query: 224 EMQGVFLNGRAIKVGPTSGQQ 244 + +G+ +K+GP +Q Sbjct: 69 S--QINFHGKKLKLGPAIRKQ 87 Score = 51.8 bits (122), Expect = 8e-07, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 5/59 (8%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG-----KCCGFVQYVDRLSAEAAIAG 367 TVF+GG+ + E E+R++F +G++ VKI K GFV + + + + + Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVES 69 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 16/90 (17%) Query: 54 NQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 N +++G +D D+ +R +A G V+++ + T ++GY FV F Sbjct: 10 NTVFVGGIDVRMDETEIRSFFARYGSVK-EVKIITDRT-----------GVSKGYGFVSF 57 Query: 114 PSSTHAANALLKNGMLIPNFPNKKLKLNWA 143 + ++++ + F KKLKL A Sbjct: 58 YNDVDVQK-IVESQIN---FHGKKLKLGPA 83 >2XS2-A nrPDB Length = 102 Score = 79.1 bits (193), Expect = 4e-15, Method: Composition-based stats. Identities = 28/81 (34%), Positives = 46/81 (56%), Gaps = 4/81 (4%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++FVG + + E+++ F RY S KI+ D+ TG+SKGYGFV F N + Q + Sbjct: 11 TVFVGGIDVRMDETEIRSFFA-RYGSVKEVKIITDR-TGVSKGYGFVSFYNDVDVQKIVE 68 Query: 224 EMQGVFLNGRAIKVGPTSGQQ 244 + +G+ +K+GP +Q Sbjct: 69 S--QINFHGKKLKLGPAIRKQ 87 Score = 51.8 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 9/83 (10%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG-----KCCGFVQYVDRLSAEAAIAGM 368 TVF+GG+ + E E+R++F +G++ VKI K GFV + + + + + Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVESQ 70 Query: 369 QGFPIANSRVRLSWGRSAKQTAL 391 +++L G + ++ L Sbjct: 71 IN--FHGKKLKL--GPAIRKQNL 89 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 16/90 (17%) Query: 54 NQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 N +++G +D D+ +R +A G V+++ + T ++GY FV F Sbjct: 10 NTVFVGGIDVRMDETEIRSFFARYGSVK-EVKIITDRT-----------GVSKGYGFVSF 57 Query: 114 PSSTHAANALLKNGMLIPNFPNKKLKLNWA 143 + ++++ + F KKLKL A Sbjct: 58 YNDVDVQK-IVESQIN---FHGKKLKLGPA 83 >2CQB-A nrPDB Length = 102 Score = 78.4 bits (191), Expect = 7e-15, Method: Composition-based stats. Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 ++VG LA V + L FI + + +I D T +G+ FV+F +++ A+ Sbjct: 15 LYVGGLAEEVDDKVLHAAFI-PFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDN 73 Query: 225 MQGVFLNGRAIKVGPTSGQQQHVSG 249 M L GR I+V + SG Sbjct: 74 MNESELFGRTIRVNLAKPMRIKESG 98 Score = 63.7 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 6/83 (7%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP------VGKCCGFVQYVDRLSAEAA 364 +++GGL+ V + L A F PFG I ++IP + FV++ A AA Sbjct: 11 TKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAA 70 Query: 365 IAGMQGFPIANSRVRLSWGRSAK 387 I M + +R++ + + Sbjct: 71 IDNMNESELFGRTIRVNLAKPMR 93 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 42/103 (40%), Gaps = 15/103 (14%) Query: 44 ASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEA-NINVRMMWNNTLNNGSRSSMGP 102 + + + TT LY+G L D + + G+ +I + + + Sbjct: 3 SGSSGMATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYET------------ 50 Query: 103 KNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATS 145 + ++G+ FV+F + AA A+ + M + +++N A Sbjct: 51 EKHRGFAFVEFELAEDAAAAI--DNMNESELFGRTIRVNLAKP 91 >6QX9-1A nrPDB Length = 282 Score = 77.6 bits (189), Expect = 1e-14, Method: Composition-based stats. Identities = 43/281 (15%), Positives = 86/281 (30%), Gaps = 58/281 (20%) Query: 158 KSGNNCSIFVGDLAPNVTESQL----FELFINRYASTSHAKIVHDQVTGMSKGYGFVKFT 213 ++ N +I++ +L + + +L + +F +++ + +G FV F Sbjct: 5 ETRPNHTIYINNLNEKIKKDELKKSLYAIF-SQFGQILDILVSRSL---KMRGQAFVIFK 60 Query: 214 NSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVS---------GNNDYNRSSSSLNNEN 264 AL MQG + +++ ++ R S Sbjct: 61 EVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPA 120 Query: 265 VDSRFLSKGQSFLSNGNNN-------MGFKRNHMSQF----------------------- 294 G + + M M Sbjct: 121 TKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQI 180 Query: 295 ---------IYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP 345 + P Q P+ +P N +F+ L E L F F V++ Sbjct: 181 PPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLV 240 Query: 346 VGKC-CGFVQYVDRLSAEAAIAGMQGFPI-ANSRVRLSWGR 384 G+ FV++ + + A AA +QGF I N+ +++S+ + Sbjct: 241 PGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAK 281 Score = 60.2 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 7/86 (8%) Query: 307 FTDPNNTTVFIGGLSSLVTEDELRA----YFQPFGTIVYVKIPVG---KCCGFVQYVDRL 359 N T++I L+ + +DEL+ F FG I+ + + + FV + + Sbjct: 4 PETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVS 63 Query: 360 SAEAAIAGMQGFPIANSRVRLSWGRS 385 SA A+ MQGFP + +R+ + ++ Sbjct: 64 SATNALRSMQGFPFYDKPMRIQYAKT 89 Score = 39.1 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 35/93 (37%), Gaps = 7/93 (7%) Query: 149 NSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYG 208 + ++ N +F+ +L E L LF N++ ++V + Sbjct: 194 QMPPAQPLSENPPNHILFLTNLPEETNELMLSMLF-NQFPGFKEVRLVPGRHD-----IA 247 Query: 209 FVKFTNSDEQQLALSEMQGVFL-NGRAIKVGPT 240 FV+F N + A +QG + A+K+ Sbjct: 248 FVEFDNEVQAGAARDALQGFKITQNNAMKISFA 280 >3NNH-A nrPDB Length = 88 Score = 77.6 bits (189), Expect = 1e-14, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 45/94 (47%), Gaps = 14/94 (14%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEA-NINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 ++++G + TW + +R+++ G INV L + S++ P ++G CFV F Sbjct: 5 KMFVGQVPRTWSEKDLRELFEQYGAVYEINV-------LRDRSQN---PPQSKGCCFVTF 54 Query: 114 PSSTHAANA--LLKNGMLIPNFPNKKLKLNWATS 145 + A A L N ++P + +++ A S Sbjct: 55 YTRKAALEAQNALHNMKVLPGM-HHPIQMKPADS 87 Score = 63.3 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 30/73 (41%), Gaps = 3/73 (4%) Query: 160 GNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTG--MSKGYGFVKFTNSDE 217 + +FVG + +E L ELF +Y + ++ D+ SKG FV F Sbjct: 1 SDAIKMFVGQVPRTWSEKDLRELFE-QYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKA 59 Query: 218 QQLALSEMQGVFL 230 A + + + + Sbjct: 60 ALEAQNALHNMKV 72 Score = 56.0 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 28/68 (41%), Gaps = 8/68 (11%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG--------KCCGFVQYVDRLSAEAAI 365 +F+G + +E +LR F+ +G + + + K C FV + R +A A Sbjct: 5 KMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 64 Query: 366 AGMQGFPI 373 + + Sbjct: 65 NALHNMKV 72 >3MDF-A nrPDB Length = 85 Score = 76.4 bits (186), Expect = 3e-14, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 ++VG LA V + L FI + + +I D T +G+ FV+F +++ A+ Sbjct: 10 LYVGGLAEEVDDKVLHAAFI-PFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDN 68 Query: 225 MQGVFLNGRAIKVG 238 M L GR I+V Sbjct: 69 MNESELFGRTIRVN 82 Score = 62.2 bits (149), Expect = 5e-10, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 6/80 (7%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP------VGKCCGFVQYVDRLSAEAA 364 +++GGL+ V + L A F PFG I ++IP + FV++ A AA Sbjct: 6 TKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAA 65 Query: 365 IAGMQGFPIANSRVRLSWGR 384 I M + +R++ + Sbjct: 66 IDNMNESELFGRTIRVNLAK 85 Score = 49.5 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 41/98 (41%), Gaps = 15/98 (15%) Query: 48 SLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEA-NINVRMMWNNTLNNGSRSSMGPKNNQ 106 S+ TT LY+G L D + + G+ +I + + + + ++ Sbjct: 2 SMATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYET------------EKHR 49 Query: 107 GYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWAT 144 G+ FV+F + AA A+ + M + +++N A Sbjct: 50 GFAFVEFELAEDAAAAI--DNMNESELFGRTIRVNLAK 85 >2KU7-A nrPDB Length = 140 Score = 76.4 bits (186), Expect = 3e-14, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 ++VG LA V + L FI + + +I D T +G+ FV+F +++ A+ Sbjct: 66 LYVGGLAEEVDDKVLHAAFI-PFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDN 124 Query: 225 MQGVFLNGRAIKVG 238 M L GR I+V Sbjct: 125 MNESELFGRTIRVN 138 Score = 61.0 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 6/77 (7%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP------VGKCCGFVQYVDRLSAEAA 364 +++GGL+ V + L A F PFG I ++IP + FV++ A AA Sbjct: 62 TKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAA 121 Query: 365 IAGMQGFPIANSRVRLS 381 I M + +R++ Sbjct: 122 IDNMNESELFGRTIRVN 138 Score = 46.8 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 39/94 (41%), Gaps = 15/94 (15%) Query: 51 TTGNQLYMGDLDPTWDKNTVRQIWASLGEA-NINVRMMWNNTLNNGSRSSMGPKNNQGYC 109 TT LY+G L D + + G+ +I + + + + ++G+ Sbjct: 61 TTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYET------------EKHRGFA 108 Query: 110 FVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWA 143 FV+F + AA A+ + M + +++N A Sbjct: 109 FVEFELAEDAAAAI--DNMNESELFGRTIRVNLA 140 >5YZG-w nrPDB Length = 174 Score = 76.0 bits (185), Expect = 4e-14, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 40/106 (37%), Gaps = 1/106 (0%) Query: 134 PNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHA 193 + ++ S + +S +FV + TE + + F Y + Sbjct: 44 EGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFA-EYGEIKNI 102 Query: 194 KIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGP 239 + D+ TG KGY V++ E Q A+ + G L G+ I V Sbjct: 103 HLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDW 148 Score = 54.9 bits (130), Expect = 8e-08, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 39/104 (37%), Gaps = 6/104 (5%) Query: 285 GFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI 344 G + + Q +F+ G+ TE+++ F +G I + + Sbjct: 45 GSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHL 104 Query: 345 PVGKCCGF------VQYVDRLSAEAAIAGMQGFPIANSRVRLSW 382 + + G+ V+Y A+AA+ G+ G + + + W Sbjct: 105 NLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDW 148 Score = 35.2 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 32/87 (36%), Gaps = 13/87 (14%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 L++ + + + +A GE N+ + + +GY V++ + Sbjct: 75 LFVTGVHEEATEEDIHDKFAEYGEIK-NIHLNLDRRTGYL----------KGYTLVEYET 123 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNW 142 A A+ G+ + + + ++W Sbjct: 124 YKEAQAAM--EGLNGQDLMGQPISVDW 148 >2EVZ-A nrPDB Length = 229 Score = 75.7 bits (184), Expect = 5e-14, Method: Composition-based stats. Identities = 45/230 (19%), Positives = 86/230 (37%), Gaps = 42/230 (18%) Query: 162 NCSIFVGDLAPN-VTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 N + V +L P VT LF LF Y KI+ ++ V+ + ++ QL Sbjct: 34 NSVLLVSNLNPERVTPQSLFILF-GVYGDVQRVKILFNKKEN-----ALVQMADGNQAQL 87 Query: 221 ALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNG 280 A+S + G L+G+ I++ + L E + + L+K Sbjct: 88 AMSHLNGHKLHGKPIRI-------------TLSKHQNVQLPREGQEDQGLTKDYG----- 129 Query: 281 NNNMGFKRNHMSQFIYPVQQQPSLNHFTD--PNNTTVFIGGLSSLVTEDELRAYFQPFGT 338 N R ++P +F + P + T+ + + V+E++L+ F G Sbjct: 130 --NSPLHR----------FKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGG 177 Query: 339 IVY--VKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIA-NSRVRLSWGRS 385 +V + +Q A A+ + + N +R+S+ +S Sbjct: 178 VVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKS 227 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 28/220 (12%), Positives = 64/220 (29%), Gaps = 50/220 (22%) Query: 50 GTTGNQLYMGDLDPT-WDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGY 108 G + L + +L+P ++ ++ G+ V++++N N Sbjct: 31 GAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQ-RVKILFNKKEN--------------- 74 Query: 109 CFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNN------------ 156 V A A+ + K +++ + Sbjct: 75 ALVQMADGNQAQLAMSH--LNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSP 132 Query: 157 ------VKSGNNCSIF-------VGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGM 203 S N +IF + ++ P+V+E L LF + K Sbjct: 133 LHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFF-----QK 187 Query: 204 SKGYGFVKFTNSDEQQLALSEMQGVFLN-GRAIKVGPTSG 242 + ++ + +E AL ++ L ++V + Sbjct: 188 DRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKS 227 Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 27/132 (20%), Positives = 51/132 (38%), Gaps = 11/132 (8%) Query: 308 TDPNNTTVFIGGL-SSLVTEDELRAYFQPFGTIVYVKIP-VGKCCGFVQYVDRLSAEAAI 365 N+ + + L VT L F +G + VKI K VQ D A+ A+ Sbjct: 30 AGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAM 89 Query: 366 AGMQGFPIANSRVRLSWGRSAKQTALLQQAM--------LSNSLQVQQQQPGLQQPNYGY 417 + + G + +R++ + + L ++ NS + ++PG + + Sbjct: 90 SHLNGHKLHGKPIRITLSKH-QNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIF 148 Query: 418 IPSSTCEAPVLP 429 PS+T +P Sbjct: 149 PPSATLHLSNIP 160 >2LEC-A nrPDB Length = 135 Score = 74.9 bits (182), Expect = 8e-14, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 S+ V +L + L +F +Y I D+ T S+G+ FV+F + + + A+ Sbjct: 48 TSLKVDNLTYRTSPDTLRRVFE-KYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAM 106 Query: 223 SEMQGVFLNGRAIKVGPTS 241 M G L+GR ++V Sbjct: 107 DAMDGAVLDGRELRVQMAR 125 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 44/116 (37%), Gaps = 11/116 (9%) Query: 283 NMGFKRNHMSQFIYPVQQ-----QPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFG 337 + + +HM+ Q T++ + L+ + D LR F+ +G Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYG 72 Query: 338 TIVYVKIPVGK------CCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAK 387 + V IP + FV++ D+ AE A+ M G + +R+ R + Sbjct: 73 RVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGR 128 Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 36/94 (38%), Gaps = 13/94 (13%) Query: 51 TTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCF 110 L + +L +T+R+++ G +V + + K ++G+ F Sbjct: 45 EGMTSLKVDNLTYRTSPDTLRRVFEKYGRVG-DVYIPRDRYT----------KESRGFAF 93 Query: 111 VDFPSSTHAANALLKNGMLIPNFPNKKLKLNWAT 144 V F A +A+ + M ++L++ A Sbjct: 94 VRFHDKRDAEDAM--DAMDGAVLDGRELRVQMAR 125 >2KN4-A nrPDB Length = 158 Score = 74.9 bits (182), Expect = 8e-14, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 S+ V +L + L +F +Y I D+ T S+G+ FV+F + + + A+ Sbjct: 71 TSLKVDNLTYRTSPDTLRRVFE-KYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAM 129 Query: 223 SEMQGVFLNGRAIKVGPTS 241 M G L+GR ++V Sbjct: 130 DAMDGAVLDGRELRVQMAR 148 Score = 55.2 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 28/134 (20%), Positives = 50/134 (37%), Gaps = 8/134 (5%) Query: 262 NENVDSRFLSKGQSFLSN--GNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGG 319 E VD+ K +N G + + F +H T++ + Sbjct: 18 TEAVDAATAEKVFKQYANDNGVDGEWTYDDATKTFTVTEGSHHHHHHMDVEGMTSLKVDN 77 Query: 320 LSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEAAIAGMQGFPI 373 L+ + D LR F+ +G + V IP + FV++ D+ AE A+ M G + Sbjct: 78 LTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVL 137 Query: 374 ANSRVRLSWGRSAK 387 +R+ R + Sbjct: 138 DGRELRVQMARYGR 151 Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 36/94 (38%), Gaps = 13/94 (13%) Query: 51 TTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCF 110 L + +L +T+R+++ G +V + + K ++G+ F Sbjct: 68 EGMTSLKVDNLTYRTSPDTLRRVFEKYGRVG-DVYIPRDRYT----------KESRGFAF 116 Query: 111 VDFPSSTHAANALLKNGMLIPNFPNKKLKLNWAT 144 V F A +A+ + M ++L++ A Sbjct: 117 VRFHDKRDAEDAM--DAMDGAVLDGRELRVQMAR 148 >3EX7-B nrPDB Length = 126 Score = 74.1 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 37/95 (38%), Gaps = 1/95 (1%) Query: 145 SSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMS 204 S + +S +FV + TE + + F Y + + D+ TG Sbjct: 5 DSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFA-EYGEIKNIHLNLDRRTGYL 63 Query: 205 KGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGP 239 KGY V++ E Q A+ + G L G+ I V Sbjct: 64 KGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDW 98 Score = 54.5 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 36/90 (40%), Gaps = 6/90 (6%) Query: 299 QQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF------ 352 Q +F+ G+ TE+++ F +G I + + + + G+ Sbjct: 9 QDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTL 68 Query: 353 VQYVDRLSAEAAIAGMQGFPIANSRVRLSW 382 V+Y A+AA+ G+ G + + + W Sbjct: 69 VEYETYKEAQAAMEGLNGQDLMGQPISVDW 98 Score = 35.2 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 32/87 (36%), Gaps = 13/87 (14%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 L++ + + + +A GE N+ + + +GY V++ + Sbjct: 25 LFVTGVHEEATEEDIHDKFAEYGEIK-NIHLNLDRRTGYL----------KGYTLVEYET 73 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNW 142 A A+ G+ + + + ++W Sbjct: 74 YKEAQAAM--EGLNGQDLMGQPISVDW 98 >1P27-B nrPDB Length = 106 Score = 74.1 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 37/95 (38%), Gaps = 1/95 (1%) Query: 145 SSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMS 204 S + +S +FV + TE + + F Y + + D+ TG Sbjct: 6 DSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFA-EYGEIKNIHLNLDRRTGYL 64 Query: 205 KGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGP 239 KGY V++ E Q A+ + G L G+ I V Sbjct: 65 KGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDW 99 Score = 54.5 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 36/90 (40%), Gaps = 6/90 (6%) Query: 299 QQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF------ 352 Q +F+ G+ TE+++ F +G I + + + + G+ Sbjct: 10 QDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTL 69 Query: 353 VQYVDRLSAEAAIAGMQGFPIANSRVRLSW 382 V+Y A+AA+ G+ G + + + W Sbjct: 70 VEYETYKEAQAAMEGLNGQDLMGQPISVDW 99 Score = 35.2 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 32/87 (36%), Gaps = 13/87 (14%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 L++ + + + +A GE N+ + + +GY V++ + Sbjct: 26 LFVTGVHEEATEEDIHDKFAEYGEIK-NIHLNLDRRTGYL----------KGYTLVEYET 74 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNW 142 A A+ G+ + + + ++W Sbjct: 75 YKEAQAAM--EGLNGQDLMGQPISVDW 99 >1QM9-A nrPDB Length = 198 Score = 74.1 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 45/230 (19%), Positives = 86/230 (37%), Gaps = 42/230 (18%) Query: 162 NCSIFVGDLAPN-VTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 N + V +L P VT LF LF Y KI+ ++ V+ + ++ QL Sbjct: 3 NSVLLVSNLNPERVTPQSLFILF-GVYGDVQRVKILFNKKEN-----ALVQMADGNQAQL 56 Query: 221 ALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNG 280 A+S + G L+G+ I++ + L E + + L+K Sbjct: 57 AMSHLNGHKLHGKPIRI-------------TLSKHQNVQLPREGQEDQGLTKDYG----- 98 Query: 281 NNNMGFKRNHMSQFIYPVQQQPSLNHFTD--PNNTTVFIGGLSSLVTEDELRAYFQPFGT 338 N R ++P +F + P + T+ + + V+E++L+ F G Sbjct: 99 --NSPLHR----------FKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGG 146 Query: 339 IVY--VKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIA-NSRVRLSWGRS 385 +V + +Q A A+ + + N +R+S+ +S Sbjct: 147 VVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKS 196 Score = 41.8 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 51/129 (39%), Gaps = 11/129 (8%) Query: 311 NNTTVFIGGL-SSLVTEDELRAYFQPFGTIVYVKIP-VGKCCGFVQYVDRLSAEAAIAGM 368 N+ + + L VT L F +G + VKI K VQ D A+ A++ + Sbjct: 2 GNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHL 61 Query: 369 QGFPIANSRVRLSWGRSAKQTALLQQAM--------LSNSLQVQQQQPGLQQPNYGYIPS 420 G + +R++ + + L ++ NS + ++PG + + PS Sbjct: 62 NGHKLHGKPIRITLSKH-QNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPS 120 Query: 421 STCEAPVLP 429 +T +P Sbjct: 121 ATLHLSNIP 129 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 27/218 (12%), Positives = 63/218 (28%), Gaps = 50/218 (22%) Query: 52 TGNQLYMGDLDPT-WDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCF 110 + L + +L+P ++ ++ G+ V++++N N Sbjct: 2 GNSVLLVSNLNPERVTPQSLFILFGVYGDVQ-RVKILFNKKEN---------------AL 45 Query: 111 VDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNN-------------- 156 V A A+ + K +++ + Sbjct: 46 VQMADGNQAQLAMSH--LNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLH 103 Query: 157 ----VKSGNNCSIF-------VGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSK 205 S N +IF + ++ P+V+E L LF + K + Sbjct: 104 RFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFF-----QKDR 158 Query: 206 GYGFVKFTNSDEQQLALSEMQGVFLN-GRAIKVGPTSG 242 ++ + +E AL ++ L ++V + Sbjct: 159 KMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKS 196 >2J0Q-D nrPDB Length = 109 Score = 73.3 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 1/75 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 +FV + TE + + F Y + + D+ TG KGY V++ E Q A+ Sbjct: 10 LFVTGVHEEATEEDIHDKFA-EYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEG 68 Query: 225 MQGVFLNGRAIKVGP 239 + G L G+ I V Sbjct: 69 LNGQDLMGQPISVDW 83 Score = 53.7 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF------VQYVDRLSAEAAIAGM 368 +F+ G+ TE+++ F +G I + + + + G+ V+Y A+AA+ G+ Sbjct: 10 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 69 Query: 369 QGFPIANSRVRLSW 382 G + + + W Sbjct: 70 NGQDLMGQPISVDW 83 Score = 35.2 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 32/87 (36%), Gaps = 13/87 (14%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 L++ + + + +A GE N+ + + +GY V++ + Sbjct: 10 LFVTGVHEEATEEDIHDKFAEYGEIK-NIHLNLDRRTGYL----------KGYTLVEYET 58 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNW 142 A A+ G+ + + + ++W Sbjct: 59 YKEAQAAM--EGLNGQDLMGQPISVDW 83 >2HYI-B nrPDB Length = 91 Score = 73.3 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 1/75 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 +FV + TE + + F Y + + D+ TG KGY V++ E Q A+ Sbjct: 12 LFVTGVHEEATEEDIHDKFA-EYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEG 70 Query: 225 MQGVFLNGRAIKVGP 239 + G L G+ I V Sbjct: 71 LNGQDLMGQPISVDW 85 Score = 53.7 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGF------VQYVDRLSAEAAIAGM 368 +F+ G+ TE+++ F +G I + + + + G+ V+Y A+AA+ G+ Sbjct: 12 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 71 Query: 369 QGFPIANSRVRLSW 382 G + + + W Sbjct: 72 NGQDLMGQPISVDW 85 Score = 35.2 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 32/87 (36%), Gaps = 13/87 (14%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 L++ + + + +A GE N+ + + +GY V++ + Sbjct: 12 LFVTGVHEEATEEDIHDKFAEYGEIK-NIHLNLDRRTGYL----------KGYTLVEYET 60 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNW 142 A A+ G+ + + + ++W Sbjct: 61 YKEAQAAM--EGLNGQDLMGQPISVDW 85 >2MYF-A nrPDB Length = 89 Score = 73.3 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 +FVG + + E L+++F + + + ++ + T ++G+ FV++ D+ + AL Sbjct: 13 LFVGGIDETIDEKSLYDIF-SSFGDIRNIEVPLNMTTKKNRGFAFVEYVEVDDAKHALYN 71 Query: 225 MQGVFLNGRAIKVGPT 240 M LNG+ I V + Sbjct: 72 MNNFELNGKRIHVNYS 87 Score = 63.3 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 23/88 (26%), Positives = 44/88 (50%), Gaps = 7/88 (7%) Query: 305 NHFTDPNNTT-VFIGGLSSLVTEDELRAYFQPFGTIVYVKIP------VGKCCGFVQYVD 357 +H +D N T +F+GG+ + E L F FG I +++P + FV+YV+ Sbjct: 2 SHMSDNNATDILFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVE 61 Query: 358 RLSAEAAIAGMQGFPIANSRVRLSWGRS 385 A+ A+ M F + R+ +++ ++ Sbjct: 62 VDDAKHALYNMNNFELNGKRIHVNYSKT 89 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 15/101 (14%) Query: 45 SNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEA-NINVRMMWNNTLNNGSRSSMGPK 103 S++S + L++G +D T D+ ++ I++S G+ NI V + +M K Sbjct: 2 SHMSDNNATDILFVGGIDETIDEKSLYDIFSSFGDIRNIEVPL------------NMTTK 49 Query: 104 NNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWAT 144 N+G+ FV++ A +AL M K++ +N++ Sbjct: 50 KNRGFAFVEYVEVDDAKHALY--NMNNFELNGKRIHVNYSK 88 >2MGZ-B nrPDB Length = 105 Score = 71.8 bits (174), Expect = 6e-13, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 158 KSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE 217 + IFVG L + ++ L E F ++ A ++ D+ T S+GYGFV + Sbjct: 12 RDTMFTKIFVGGLPYHTSDKTLHEYFE-QFGDIEEAVVITDRNTQKSRGYGFVTMKDRAS 70 Query: 218 QQLALSEMQGVFLNGRAIKVG 238 + A + + ++GR V Sbjct: 71 AERACKDPNPI-IDGRKANVN 90 Score = 50.6 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 7/79 (8%) Query: 309 DPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAE 362 D T +F+GGL ++ L YF+ FG I + + GFV DR SAE Sbjct: 13 DTMFTKIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAE 72 Query: 363 AAIAGMQGFPIANSRVRLS 381 A I + ++ Sbjct: 73 RACKD-PNPIIDGRKANVN 90 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 32/98 (32%), Gaps = 14/98 (14%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFP 114 ++++G L T+ + + G+ V + NT + ++GY FV Sbjct: 18 KIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNT-----------QKSRGYGFVTMK 66 Query: 115 SSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNN 152 A A P +K +N A N Sbjct: 67 DRASAERACKDPN---PIIDGRKANVNLAYLGAKPRTN 101 >6ASO-A nrPDB Length = 424 Score = 71.0 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 51/365 (13%), Positives = 115/365 (31%), Gaps = 72/365 (19%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 L+M + P++ + +R + + +++R+ S+ ++ + ++D S Sbjct: 93 LWMTNFPPSYTQRNIRDLLQDINVVALSIRL-----------PSLRFNTSRRFAYIDVTS 141 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNV- 174 A + K L K++ ++++ + I + +L+ + Sbjct: 142 KEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGR-----EIMIRNLSTELL 196 Query: 175 TESQLFELFINRYASTSHAKIVHDQVT-GMSKGYGFVKFTNSDEQQLALSEMQGVFLNGR 233 E+ L E F + S I Q + F+ F N D + AL M L R Sbjct: 197 DENLLRESFEG-FGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNR 254 Query: 234 AIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQ 293 I V + ++ N+ R +S N++ +++ Sbjct: 255 EISV--SLADKKPFLERNEVKRLLASRNSKELETLI------------------------ 288 Query: 294 FIYPVQQQPSLNHFTDPNNTTVFIGGLSSL--VTEDELRAYFQPFGTIVYVKIPVGKCCG 351 L +D + ++ L + E ++R + Sbjct: 289 ---------CLFPLSDKVSPSLICQFLQEEIHINEKDIRKIL----------LVSDFNGA 329 Query: 352 FVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQ-----VQQQ 406 + + D A + + G +R K+ QQ ++ + ++ Sbjct: 330 IIIFRDSKFAAKMLMILNGSQFQGKVIRSGTINDMKRYYNNQQNHSMKHVKPSCINMMEK 389 Query: 407 QPGLQ 411 P LQ Sbjct: 390 GPNLQ 394 Score = 47.2 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 19/136 (13%), Positives = 54/136 (39%), Gaps = 6/136 (4%) Query: 162 NCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLA 221 C++++ + P+ T+ + +L + ++ + S+ + ++ T+ ++ + Sbjct: 90 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRF-NTSRRFAYIDVTSKEDARYC 148 Query: 222 LSEMQGVFLNGRAI--KVGPTSGQQQHVSGNNDYNRSSS--SLNNENVDSRFLSKGQ-SF 276 + ++ G+ + G + KV + + R +L+ E +D L + F Sbjct: 149 VEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGF 208 Query: 277 LSNGNNNMGFKRNHMS 292 S N+ + S Sbjct: 209 GSIEKINIPAGQKEHS 224 Score = 37.5 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 28/74 (37%), Gaps = 4/74 (5%) Query: 309 DPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP----VGKCCGFVQYVDRLSAEAA 364 + TTV + L ++++ YF+ G I++V + +++ A AA Sbjct: 11 NRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRFARIEFARYDGALAA 70 Query: 365 IAGMQGFPIANSRV 378 I N + Sbjct: 71 ITKTHKVVGQNEII 84 >2DH8-A nrPDB Length = 105 Score = 70.3 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 2/86 (2%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 +FVG L + T+ L F ++Y I+ D+ T S+G+GFVKF + + L+ Sbjct: 18 KLFVGGLDWSTTQETLRSYF-SQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLA 76 Query: 224 EMQGVFLNGRAIKVGPTSGQQQHVSG 249 + L+GR I P + + SG Sbjct: 77 S-RPHTLDGRNIDPKPCTPRGMQPSG 101 Score = 47.9 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 6/54 (11%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI------PVGKCCGFVQYVDR 358 +F+GGL T++ LR+YF +G +V I + GFV++ D Sbjct: 15 EIGKLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDP 68 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 39/98 (39%), Gaps = 16/98 (16%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFP 114 +L++G LD + + T+R ++ GE ++ +M + T N ++G+ FV F Sbjct: 18 KLFVGGLDWSTTQETLRSYFSQYGEV-VDCVIMKDKTTN----------QSRGFGFVKFK 66 Query: 115 SSTH-----AANALLKNGMLIPNFPNKKLKLNWATSSY 147 A+ +G I P + + S Sbjct: 67 DPNCVGTVLASRPHTLDGRNIDPKPCTPRGMQPSGPSS 104 >6EM1-o nrPDB Length = 220 Score = 69.9 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 21/105 (20%), Positives = 42/105 (40%), Gaps = 1/105 (0%) Query: 134 PNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHA 193 K+K + + + I+V L E +L + F ++ Sbjct: 62 GTHKIKRLNPKKQANEKKSKDKKTLEEYSGIIYVSRLPHGFHEKELSKYFA-QFGDLKEV 120 Query: 194 KIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVG 238 ++ ++ TG S+ YGF++F N ++ +A M L G ++V Sbjct: 121 RLARNKKTGNSRHYGFLEFVNKEDAMIAQESMNNYLLMGHLLQVR 165 Score = 51.8 bits (122), Expect = 8e-07, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 37/88 (42%), Gaps = 6/88 (6%) Query: 299 QQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKC------CGF 352 +++ + + +++ L E EL YF FG + V++ K GF Sbjct: 77 EKKSKDKKTLEEYSGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGF 136 Query: 353 VQYVDRLSAEAAIAGMQGFPIANSRVRL 380 +++V++ A A M + + +++ Sbjct: 137 LEFVNKEDAMIAQESMNNYLLMGHLLQV 164 >2DGP-A nrPDB Length = 106 Score = 69.1 bits (167), Expect = 5e-12, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 39/94 (41%), Gaps = 4/94 (4%) Query: 150 SNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGF 209 ++ + +K + +F+G + N+ E L LF + ++ D+ TGM KG F Sbjct: 1 GSSGSSGMKDHDAIKLFIGQIPRNLDEKDLKPLFE-EFGKIYELTVLKDRFTGMHKGCAF 59 Query: 210 VKFTNSDEQQLALSEMQGVFL---NGRAIKVGPT 240 + + + A S + R I+V P Sbjct: 60 LTYCERESALKAQSALHEQKTLPGMNRPIQVKPA 93 Score = 59.1 bits (141), Expect = 5e-09, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 37/87 (42%), Gaps = 9/87 (10%) Query: 304 LNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVD 357 + D + +FIG + + E +L+ F+ FG I + + K C F+ Y + Sbjct: 5 SSGMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCE 64 Query: 358 RLSAEAAIAGMQGF---PIANSRVRLS 381 R SA A + + P N +++ Sbjct: 65 RESALKAQSALHEQKTLPGMNRPIQVK 91 Score = 51.8 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 12/92 (13%), Positives = 35/92 (38%), Gaps = 14/92 (15%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFP 114 +L++G + D+ ++ ++ G+ + ++ + ++G F+ + Sbjct: 15 KLFIGQIPRNLDEKDLKPLFEEFGKI-YELTVLKDRFTG----------MHKGCAFLTYC 63 Query: 115 SSTHAANA--LLKNGMLIPNFPNKKLKLNWAT 144 A A L +P N+ +++ A Sbjct: 64 ERESALKAQSALHEQKTLPGM-NRPIQVKPAD 94 >2ERR-A nrPDB Length = 109 Score = 68.7 bits (166), Expect = 6e-12, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 42/100 (42%), Gaps = 9/100 (9%) Query: 144 TSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGM 203 S+ N+ N + V ++ + L ++F ++ +I+ Sbjct: 17 RGSHMNTENKSQPK------RLHVSNIPFRFRDPDLRQMF-GQFGKILDVEII--FNERG 67 Query: 204 SKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQ 243 SKG+GFV F NS + A ++ G + GR I+V + + Sbjct: 68 SKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATAR 107 Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 36/87 (41%), Gaps = 7/87 (8%) Query: 302 PSLNHFTDPNNTT---VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG----KCCGFVQ 354 P +H N + + + + + +LR F FG I+ V+I K GFV Sbjct: 16 PRGSHMNTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVT 75 Query: 355 YVDRLSAEAAIAGMQGFPIANSRVRLS 381 + + A+ A + G + ++ ++ Sbjct: 76 FENSADADRAREKLHGTVVEGRKIEVN 102 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 44/92 (47%), Gaps = 15/92 (16%) Query: 54 NQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 +L++ ++ + +RQ++ G+ ++V +++N + ++G+ FV F Sbjct: 30 KRLHVSNIPFRFRDPDLRQMFGQFGKI-LDVEIIFNE------------RGSKGFGFVTF 76 Query: 114 PSSTHAANALLKNGMLIPNFPNKKLKLNWATS 145 +S A A + + +K+++N AT+ Sbjct: 77 ENSADADRA--REKLHGTVVEGRKIEVNNATA 106 >6QX9-1K nrPDB Length = 437 Score = 68.7 bits (166), Expect = 6e-12, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++FV + + TES+L F Y +V+ + +G +GY F+++ + + A Sbjct: 104 TLFVARVNYDTTESKLRREFE-VYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYK 162 Query: 224 EMQGVFLNGRAIKVGPTSGQ 243 G ++GR + V G+ Sbjct: 163 HADGKKIDGRRVLVDVERGR 182 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 8/82 (9%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEAAIAG 367 T+F+ ++ TE +LR F+ +G I + + K F++Y +A Sbjct: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163 Query: 368 MQGFPIANSRVRLS--WGRSAK 387 G I RV + GR+ K Sbjct: 164 ADGKKIDGRRVLVDVERGRTVK 185 >3CW1-K nrPDB Length = 216 Score = 68.7 bits (166), Expect = 6e-12, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++FV + + TES+L F Y +V+ + +G +GY F+++ + + A Sbjct: 104 TLFVARVNYDTTESKLRREFE-VYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYK 162 Query: 224 EMQGVFLNGRAIKVGPTSGQ 243 G ++GR + V G+ Sbjct: 163 HADGKKIDGRRVLVDVERGR 182 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 8/82 (9%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK------CCGFVQYVDRLSAEAAIAG 367 T+F+ ++ TE +LR F+ +G I + + K F++Y +A Sbjct: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163 Query: 368 MQGFPIANSRVRLS--WGRSAK 387 G I RV + GR+ K Sbjct: 164 ADGKKIDGRRVLVDVERGRTVK 185 >2DGQ-A nrPDB Length = 108 Score = 68.3 bits (165), Expect = 7e-12, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 4/95 (4%) Query: 158 KSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE 217 K + +FVG + + E L LF + ++ D++TG+ KG F+ + D Sbjct: 11 KDHDAIKLFVGQIPRGLDEQDLKPLFE-EFGRIYELTVLKDRLTGLHKGCAFLTYCARDS 69 Query: 218 QQLALSEMQGVFL---NGRAIKVGPTSGQQQHVSG 249 A S + R I+V P + + + SG Sbjct: 70 ALKAQSALHEQKTLPGMNRPIQVKPAASEGRGESG 104 Score = 59.1 bits (141), Expect = 5e-09, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 37/92 (40%), Gaps = 9/92 (9%) Query: 306 HFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRL 359 D + +F+G + + E +L+ F+ FG I + + K C F+ Y R Sbjct: 9 PMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARD 68 Query: 360 SAEAAIAGMQGF---PIANSRVRLSWGRSAKQ 388 SA A + + P N +++ S + Sbjct: 69 SALKAQSALHEQKTLPGMNRPIQVKPAASEGR 100 Score = 49.1 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 16/106 (15%), Positives = 41/106 (38%), Gaps = 15/106 (14%) Query: 43 GASNVSLGTTGN-QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMG 101 G+S V + +L++G + D+ ++ ++ G + ++ + Sbjct: 4 GSSGVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRI-YELTVLKDRLTG-------- 54 Query: 102 PKNNQGYCFVDFPSSTHAANA--LLKNGMLIPNFPNKKLKLNWATS 145 ++G F+ + + A A L +P N+ +++ A S Sbjct: 55 --LHKGCAFLTYCARDSALKAQSALHEQKTLPGM-NRPIQVKPAAS 97 >2RS2-A nrPDB Length = 109 Score = 68.3 bits (165), Expect = 7e-12, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Query: 160 GNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQ 219 + C +F+G L+ T+ L E F ++ ++ D +T S+G+GFV F + Sbjct: 23 SSGCKMFIGGLSWQTTQEGLREYF-GQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVD 81 Query: 220 LALSEMQGVFLNGRAI--KVGPTSGQQ 244 L++ + L+ + I KV Q Sbjct: 82 KVLAQSR-HELDSKTIDPKVAFPRRAQ 107 Score = 47.9 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 7/68 (10%) Query: 302 PSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQY 355 P +H + +FIGGLS T++ LR YF FG + + + GFV + Sbjct: 16 PRGSHMGS-SGCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTF 74 Query: 356 VDRLSAEA 363 +D+ + Sbjct: 75 MDQAGVDK 82 Score = 37.1 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 38/101 (37%), Gaps = 14/101 (13%) Query: 49 LGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGY 108 +G++G ++++G L + +R+ + GE + +M + K ++G+ Sbjct: 21 MGSSGCKMFIGGLSWQTTQEGLREYFGQFGEVKECL-VMRDPLT----------KRSRGF 69 Query: 109 CFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSN 149 FV F L ++ +K + A + Sbjct: 70 GFVTFMDQAGVDKVLAQS---RHELDSKTIDPKVAFPRRAQ 107 >2MKI-A nrPDB Length = 203 Score = 68.3 bits (165), Expect = 7e-12, Method: Composition-based stats. Identities = 36/185 (19%), Positives = 68/185 (36%), Gaps = 19/185 (10%) Query: 49 LGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGY 108 + ++++G L P D++ + + G ++ + S+S PK GY Sbjct: 8 VERYSRKVFVGGLPPDIDEDEITASFRRFG------PLIVDWPHKAESKSYFPPK---GY 58 Query: 109 CFVDFPSSTHA----ANALLKNGMLI-----PNFPNKKLKLNWATSSYSNSNNSLNNVKS 159 F+ F + + ++G L P +K +++ S S+ + Sbjct: 59 AFLLFQDESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLD 118 Query: 160 GNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQ 219 +IFVG + + +L + Y +A I D KG G V F+N Sbjct: 119 PRK-TIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYI 177 Query: 220 LALSE 224 A+S Sbjct: 178 AAISA 182 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 26/63 (41%), Gaps = 8/63 (12%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTI--------VYVKIPVGKCCGFVQYVDRLSAEAA 364 VF+GGL + EDE+ A F+ FG + K F+ + D S +A Sbjct: 13 RKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQAL 72 Query: 365 IAG 367 I Sbjct: 73 IDA 75 >1UAW-A nrPDB Length = 77 Score = 68.3 bits (165), Expect = 8e-12, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 2/73 (2%) Query: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 C +F+G L+ T+ L E F ++ ++ D +T S+G+GFV F + L Sbjct: 1 CKMFIGGLSWQTTQEGLREYF-GQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVL 59 Query: 223 SEMQGVFLNGRAI 235 ++ + L+ + I Sbjct: 60 AQSR-HELDSKTI 71 Score = 46.0 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 6/56 (10%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYVDRLSAEA 363 +FIGGLS T++ LR YF FG + + + GFV ++D+ + Sbjct: 2 KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDK 57 Score = 32.5 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 26/70 (37%), Gaps = 11/70 (15%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFP 114 ++++G L + +R+ + GE + +M + K ++G+ FV F Sbjct: 2 KMFIGGLSWQTTQEGLREYFGQFGEVKECL-VMRDPLT----------KRSRGFGFVTFM 50 Query: 115 SSTHAANALL 124 L Sbjct: 51 DQAGVDKVLA 60 >1RK8-A nrPDB Length = 165 Score = 68.3 bits (165), Expect = 8e-12, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 39/100 (39%), Gaps = 2/100 (2%) Query: 141 NWATSSYSNSNN-SLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQ 199 ++ + + +S +FV + E ++ E F Y + + D+ Sbjct: 50 SYERVRNEDDDELEPGPQRSVEGWILFVTSIHEEAQEDEIQEKFC-DYGEIKNIHLNLDR 108 Query: 200 VTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGP 239 TG SKGY V++ + A + G + G+ I+V Sbjct: 109 RTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDW 148 Score = 52.5 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 43/122 (35%), Gaps = 18/122 (14%) Query: 272 KGQSFLSNGNNNMGFK-----RNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTE 326 KG+ F S+ N RN + P +F+ + E Sbjct: 34 KGRGFGSDSNTREAIHSYERVRNEDDDELEP-------GPQRSVEGWILFVTSIHEEAQE 86 Query: 327 DELRAYFQPFGTIVYVKIPVGKCCGF------VQYVDRLSAEAAIAGMQGFPIANSRVRL 380 DE++ F +G I + + + + GF V+Y A AA + G I +++ Sbjct: 87 DEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQV 146 Query: 381 SW 382 W Sbjct: 147 DW 148 Score = 36.0 bits (81), Expect = 0.047, Method: Composition-based stats. Identities = 11/87 (12%), Positives = 34/87 (39%), Gaps = 13/87 (14%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 L++ + ++ +++ + GE N+ + + ++GY V++ + Sbjct: 75 LFVTSIHEEAQEDEIQEKFCDYGEIK-NIHLNLDRRTG----------FSKGYALVEYET 123 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNW 142 A A K + + ++++W Sbjct: 124 HKQALAA--KEALNGAEIMGQTIQVDW 148 >1OO0-B nrPDB Length = 110 Score = 68.3 bits (165), Expect = 8e-12, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 39/100 (39%), Gaps = 2/100 (2%) Query: 141 NWATSSYSNSNN-SLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQ 199 ++ + + +S +FV + E ++ E F Y + + D+ Sbjct: 4 SYERVRNEDDDELEPGPQRSVEGWILFVTSIHEEAQEDEIQEKFC-DYGEIKNIHLNLDR 62 Query: 200 VTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGP 239 TG SKGY V++ + A + G + G+ I+V Sbjct: 63 RTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDW 102 Score = 49.5 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 36/101 (35%), Gaps = 13/101 (12%) Query: 288 RNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG 347 RN + P +F+ + EDE++ F +G I + + + Sbjct: 9 RNEDDDELEP-------GPQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLD 61 Query: 348 KCCGF------VQYVDRLSAEAAIAGMQGFPIANSRVRLSW 382 + GF V+Y A AA + G I +++ W Sbjct: 62 RRTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDW 102 Score = 36.0 bits (81), Expect = 0.047, Method: Composition-based stats. Identities = 11/87 (12%), Positives = 34/87 (39%), Gaps = 13/87 (14%) Query: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 L++ + ++ +++ + GE N+ + + ++GY V++ + Sbjct: 29 LFVTSIHEEAQEDEIQEKFCDYGEIK-NIHLNLDRRTG----------FSKGYALVEYET 77 Query: 116 STHAANALLKNGMLIPNFPNKKLKLNW 142 A A K + + ++++W Sbjct: 78 HKQALAA--KEALNGAEIMGQTIQVDW 102 >2CQ3-A nrPDB Length = 103 Score = 68.0 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 + V ++ + L ++F ++ +I+ SKG+GFV F NS + A Sbjct: 17 RLHVSNIPFRFRDPDLRQMF-GQFGKILDVEII--FNERGSKGFGFVTFENSADADRARE 73 Query: 224 EMQGVFLNGRAIKVGPTSGQ 243 ++ G + GR I+V + + Sbjct: 74 KLHGTVVEGRKIEVNNATAR 93 Score = 54.5 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Query: 315 VFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG----KCCGFVQYVDRLSAEAAIAGMQG 370 + + + + +LR F FG I+ V+I K GFV + + A+ A + G Sbjct: 18 LHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHG 77 Query: 371 FPIANSRVRLS 381 + ++ ++ Sbjct: 78 TVVEGRKIEVN 88 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 45/94 (47%), Gaps = 15/94 (15%) Query: 52 TGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFV 111 T +L++ ++ + +RQ++ G+ ++V +++N + ++G+ FV Sbjct: 14 TPKRLHVSNIPFRFRDPDLRQMFGQFGKI-LDVEIIFNE------------RGSKGFGFV 60 Query: 112 DFPSSTHAANALLKNGMLIPNFPNKKLKLNWATS 145 F +S A A + + +K+++N AT+ Sbjct: 61 TFENSADADRA--REKLHGTVVEGRKIEVNNATA 92 >6FYY-r nrPDB Length = 274 Score = 66.0 bits (159), Expect = 4e-11, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 48/114 (42%), Gaps = 2/114 (1%) Query: 130 IPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYAS 189 IP + A S + ++ + + C++ + + N E+ L E + +A Sbjct: 160 IPGQYVPPSRRAGARDPSS--DAYRDSRERDDMCTLKIMQVNENADENSLREELLFPFAP 217 Query: 190 TSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQ 243 +V ++ TG S+G FV F++ + + AL + G ++V + + Sbjct: 218 IPRVSVVRNKETGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPK 271 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 34/95 (35%), Gaps = 8/95 (8%) Query: 297 PVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRA-YFQPFGTIVYVKIPVGK------C 349 P + D + T+ I ++ E+ LR PF I V + K Sbjct: 176 PSSDAYRDSRERD-DMCTLKIMQVNENADENSLREELLFPFAPIPRVSVVRNKETGKSRG 234 Query: 350 CGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGR 384 FV + AE A+ + G N +R+ W + Sbjct: 235 LAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSK 269 >2DH9-A nrPDB Length = 89 Score = 66.0 bits (159), Expect = 4e-11, Method: Composition-based stats. Identities = 29/92 (31%), Positives = 40/92 (43%), Gaps = 3/92 (3%) Query: 158 KSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE 217 S + IFV +L + T L + F N +A I + G SKG G VKF + + Sbjct: 1 GSSGSSGIFVRNLPFDFTWKMLKDKF-NECGHVLYADIKME--NGKSKGCGVVKFESPEV 57 Query: 218 QQLALSEMQGVFLNGRAIKVGPTSGQQQHVSG 249 + A M G+ L+GR I V SG Sbjct: 58 AERACRMMNGMKLSGREIDVRIDRNASGPSSG 89 Score = 48.7 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 33/80 (41%), Gaps = 4/80 (5%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI----PVGKCCGFVQYVDRLSAEAAIA 366 ++ +F+ L T L+ F G ++Y I K CG V++ AE A Sbjct: 4 GSSGIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACR 63 Query: 367 GMQGFPIANSRVRLSWGRSA 386 M G ++ + + R+A Sbjct: 64 MMNGMKLSGREIDVRIDRNA 83 >6C8U-1 nrPDB Length = 115 Score = 65.6 bits (158), Expect = 4e-11, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 36/87 (41%), Gaps = 4/87 (4%) Query: 160 GNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQ 219 N +F+G L+ + L + F +++ ++ D T S+G+GFV F + Sbjct: 22 SNAGKMFIGGLSWQTSPDSLRDYF-SKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVD 80 Query: 220 LALSEMQGVFLNGRAI--KVGPTSGQQ 244 L + L+ + I KV Q Sbjct: 81 KVLGQPH-HELDSKTIDPKVAFPRRAQ 106 Score = 48.7 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 6/67 (8%) Query: 303 SLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG------KCCGFVQYV 356 + N + N +FIGGLS + D LR YF FG I + + GFV + Sbjct: 15 TENLYFQSNAGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFA 74 Query: 357 DRLSAEA 363 D S + Sbjct: 75 DPASVDK 81 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 19/116 (16%), Positives = 38/116 (32%), Gaps = 14/116 (12%) Query: 43 GASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGP 102 G N+ + ++++G L +++R ++ GE +M + T Sbjct: 14 GTENLYFQSNAGKMFIGGLSWQTSPDSLRDYFSKFGEIR-ECMVMRDPTT---------- 62 Query: 103 KNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVK 158 K ++G+ FV F L G +K + A + K Sbjct: 63 KRSRGFGFVTFADPASVDKVL---GQPHHELDSKTIDPKVAFPRRAQPKMVTRTKK 115 >2I2Y-A nrPDB Length = 150 Score = 65.6 bits (158), Expect = 5e-11, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 40/83 (48%), Gaps = 6/83 (7%) Query: 162 NCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLA 221 +C ++VG+L N +++L F Y + + G+ FV+F + + A Sbjct: 73 DCKVYVGNLGNNGNKTELERAF-GYYGPLRSVWVARNPP-----GFAFVEFEDPRDAADA 126 Query: 222 LSEMQGVFLNGRAIKVGPTSGQQ 244 + E+ G L G ++V ++G++ Sbjct: 127 VRELDGRTLCGCRVRVELSNGEK 149 Score = 54.5 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 34/80 (42%), Gaps = 1/80 (1%) Query: 310 PNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGK-CCGFVQYVDRLSAEAAIAGM 368 P + V++G L + + EL F +G + V + FV++ D A A+ + Sbjct: 71 PLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVREL 130 Query: 369 QGFPIANSRVRLSWGRSAKQ 388 G + RVR+ K+ Sbjct: 131 DGRTLCGCRVRVELSNGEKR 150 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 16/69 (23%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFP 114 ++Y+G+L +K + + + G RS +N G+ FV+F Sbjct: 75 KVYVGNLGNNGNKTELERAFGYYGPL----------------RSVWVARNPPGFAFVEFE 118 Query: 115 SSTHAANAL 123 AA+A+ Sbjct: 119 DPRDAADAV 127 >4ZKA-A nrPDB Length = 100 Score = 65.3 bits (157), Expect = 6e-11, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 38/89 (42%), Gaps = 3/89 (3%) Query: 155 NNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTN 214 N + V ++ + L ++F ++ +I+ SKG+GFV F N Sbjct: 1 NTENKSQPKRLHVSNIPFRFRDPDLRQMF-GQFGKILDVEII--FNERGSKGFGFVTFEN 57 Query: 215 SDEQQLALSEMQGVFLNGRAIKVGPTSGQ 243 S + A ++ G + GR I+V + + Sbjct: 58 SADADRAREKLHGTVVEGRKIEVNNATAR 86 Score = 53.3 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 32/81 (39%), Gaps = 4/81 (4%) Query: 305 NHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG----KCCGFVQYVDRLS 360 N + + + + +LR F FG I+ V+I K GFV + + Sbjct: 1 NTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSAD 60 Query: 361 AEAAIAGMQGFPIANSRVRLS 381 A+ A + G + ++ ++ Sbjct: 61 ADRAREKLHGTVVEGRKIEVN 81 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 44/92 (47%), Gaps = 15/92 (16%) Query: 54 NQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 +L++ ++ + +RQ++ G+ ++V +++N + ++G+ FV F Sbjct: 9 KRLHVSNIPFRFRDPDLRQMFGQFGKI-LDVEIIFNE------------RGSKGFGFVTF 55 Query: 114 PSSTHAANALLKNGMLIPNFPNKKLKLNWATS 145 +S A A + + +K+++N AT+ Sbjct: 56 ENSADADRA--REKLHGTVVEGRKIEVNNATA 85 >2DGS-A nrPDB Length = 99 Score = 64.9 bits (156), Expect = 8e-11, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 IFVG + N E++L E F ++ + +++D +G+GF+ F + A+ Sbjct: 12 KIFVGGIPHNCGETELREYF-KKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAV- 69 Query: 224 EMQGVFLNGRAIKVGPTSGQQQHVSG 249 M + G+ ++V + SG Sbjct: 70 NMHFHDIMGKKVEVKRAEPRDSKSSG 95 Score = 53.3 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 9/84 (10%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP------VGKCCGFVQYVDRLSAEAAIAG 367 +F+GG+ E ELR YF+ FG + V + + GF+ + D S + A+ Sbjct: 12 KIFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVN- 70 Query: 368 MQGFPIANSRVRLSWG--RSAKQT 389 M I +V + R +K + Sbjct: 71 MHFHDIMGKKVEVKRAEPRDSKSS 94 Score = 44.5 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 16/97 (16%), Positives = 35/97 (36%), Gaps = 14/97 (14%) Query: 54 NQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 N++++G + + +R+ + G V M+++ G+ F+ F Sbjct: 11 NKIFVGGIPHNCGETELREYFKKFGVV-TEVVMIYDAEKQRPR----------GFGFITF 59 Query: 114 PSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNS 150 A+ M + KK+++ A S S Sbjct: 60 EDEQSVDQAV---NMHFHDIMGKKVEVKRAEPRDSKS 93 >4WKR-A nrPDB Length = 208 Score = 62.9 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 26/137 (18%), Positives = 52/137 (37%), Gaps = 3/137 (2%) Query: 93 NNGSRSSMGPKNNQGYCFVDFPSSTHAANALLKNGMLIPN--FPNKKLKLNWATSSYSNS 150 + K+ GY + S + L +G LI + ++L+ + Sbjct: 53 KDRFLREQIEKSRDGYVDISLLVSFNKMKKLTTDGKLIARALRSSAVVELDLEGTRIRRK 112 Query: 151 NNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFV 210 K + +++V L NV S + +F + + + I H + TG KG+ FV Sbjct: 113 KPLGERPKDEDERTVYVELLPKNVNHSWIERVF-GKCGNVVYISIPHYKSTGDPKGFAFV 171 Query: 211 KFTNSDEQQLALSEMQG 227 +F ++ A+ + Sbjct: 172 EFETKEQAAKAIEFLNN 188 Score = 51.4 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 31/79 (39%), Gaps = 6/79 (7%) Query: 300 QQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPV------GKCCGFV 353 ++P D + TV++ L V + F G +VY+ IP K FV Sbjct: 112 KKPLGERPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFV 171 Query: 354 QYVDRLSAEAAIAGMQGFP 372 ++ + A AI + P Sbjct: 172 EFETKEQAAKAIEFLNNPP 190 >1X4A-A nrPDB Length = 109 Score = 62.9 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 43/84 (51%), Gaps = 5/84 (5%) Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 N+C I+VG+L P++ + ++F +Y + + ++ G + FV+F + + + Sbjct: 21 NDCRIYVGNLPPDIRTKDIEDVFY-KYGAIRDIDL-KNRRGGPP--FAFVEFEDPRDAED 76 Query: 221 ALSEMQGVFLNGRAIKVG-PTSGQ 243 A+ G +G ++V P SG+ Sbjct: 77 AVYGRDGYDYDGYRLRVEFPRSGR 100 Score = 61.8 bits (148), Expect = 6e-10, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 38/86 (44%), Gaps = 3/86 (3%) Query: 307 FTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKC---CGFVQYVDRLSAEA 363 N+ +++G L + ++ F +G I + + + FV++ D AE Sbjct: 17 PAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAED 76 Query: 364 AIAGMQGFPIANSRVRLSWGRSAKQT 389 A+ G G+ R+R+ + RS + T Sbjct: 77 AVYGRDGYDYDGYRLRVEFPRSGRGT 102 Score = 44.1 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 36/97 (37%), Gaps = 16/97 (16%) Query: 50 GTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYC 109 G ++Y+G+L P + ++ G + L N GP + Sbjct: 19 GNNDCRIYVGNLPPDIRTKDIEDVFYKYGAI-------RDIDLKNRR---GGPP----FA 64 Query: 110 FVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSS 146 FV+F A +A+ G ++ +L++ + S Sbjct: 65 FVEFEDPRDAEDAVY--GRDGYDYDGYRLRVEFPRSG 99 >2MMY-A nrPDB Length = 97 Score = 62.6 bits (150), Expect = 4e-10, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 36/94 (38%), Gaps = 9/94 (9%) Query: 160 GNNCSIFVGDLAPNVTESQLFELFINRYASTSH--------AKIVHDQVTGMSKGYGFVK 211 +N +IFV L V+ Q+ E F + + D+ TG KG V Sbjct: 5 SDNNTIFVQGLGEGVSTDQVGEFF-KQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVS 63 Query: 212 FTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQ 245 F + + A+ G +G IKV + + + Sbjct: 64 FDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPE 97 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 35/90 (38%), Gaps = 14/90 (15%) Query: 308 TDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVY--------------VKIPVGKCCGFV 353 +N T+F+ GL V+ D++ +F+ G I K V Sbjct: 3 HMSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 62 Query: 354 QYVDRLSAEAAIAGMQGFPIANSRVRLSWG 383 + D SA+AAI G + +++S+ Sbjct: 63 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFA 92 >2DO0-A nrPDB Length = 114 Score = 61.8 bits (148), Expect = 7e-10, Method: Composition-based stats. Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%) Query: 146 SYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSK 205 S S+ +L + G+ ++FV +L V +L E+F + A I+ D+ G S+ Sbjct: 1 GSSGSSGALQAGRLGS--TVFVANLDYKVGWKKLKEVF-SMAGVVVRADILEDK-DGKSR 56 Query: 206 GYGFVKFTNSDEQQLALSEMQGVFLNGRAIKV 237 G G V F S E A+S G L R + V Sbjct: 57 GIGTVTFEQSIEAVQAISMFNGQLLFDRPMHV 88 Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 29/75 (38%), Gaps = 5/75 (6%) Query: 312 NTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIP-----VGKCCGFVQYVDRLSAEAAIA 366 +TVF+ L V +L+ F G +V I + G V + + A AI+ Sbjct: 15 GSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAIS 74 Query: 367 GMQGFPIANSRVRLS 381 G + + + + Sbjct: 75 MFNGQLLFDRPMHVK 89 >2CQH-A nrPDB Length = 93 Score = 61.8 bits (148), Expect = 7e-10, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 44/93 (47%), Gaps = 8/93 (8%) Query: 158 KSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE 217 S +++G+L+P VT L +LF +R + ++ GY FV + + + Sbjct: 4 GSSGMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLK-------SGYAFVDYPDQNW 56 Query: 218 QQLALSEMQG-VFLNGRAIKVGPTSGQQQHVSG 249 A+ + G V L+G+ ++V + ++ SG Sbjct: 57 AIRAIETLSGKVELHGKIMEVDYSVSKKLRSSG 89 Score = 42.1 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 1/75 (1%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFP- 372 ++IG LS VT D+LR F + ++ + FV Y D+ A AI + G Sbjct: 10 KLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGKVE 69 Query: 373 IANSRVRLSWGRSAK 387 + + + + S K Sbjct: 70 LHGKIMEVDYSVSKK 84 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 23/102 (22%) Query: 43 GASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGP 102 G+S S N+LY+G+L P + +RQ++ G+ + + L + Sbjct: 1 GSSGSS---GMNKLYIGNLSPAVTADDLRQLF---GDRKL--PLAGQVLLKS-------- 44 Query: 103 KNNQGYCFVDFPSSTHAANAL-LKNGMLIPNFPNKKLKLNWA 143 GY FVD+P A A+ +G + K ++++++ Sbjct: 45 ----GYAFVDYPDQNWAIRAIETLSGKV--ELHGKIMEVDYS 80 >2LCW-A nrPDB Length = 116 Score = 58.3 bits (139), Expect = 7e-09, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 36/99 (36%), Gaps = 9/99 (9%) Query: 156 NVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSH--------AKIVHDQVTGMSKGY 207 + +N +IFV L NVT + + F + + D+ TG KG Sbjct: 1 EQDNSDNNTIFVQGLGENVTIESVADYF-KQIGIIKTNKKTGQPMINLYTDRETGKLKGE 59 Query: 208 GFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQH 246 V F + + A+ G +G IKV + + Sbjct: 60 ATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADF 98 Score = 38.3 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 14/92 (15%) Query: 306 HFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVK--------------IPVGKCCG 351 + +N T+F+ GL VT + + YF+ G I K K Sbjct: 1 EQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEA 60 Query: 352 FVQYVDRLSAEAAIAGMQGFPIANSRVRLSWG 383 V + D SA+AAI G + + +++S+ Sbjct: 61 TVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFA 92 >3JB9-k nrPDB Length = 111 Score = 58.3 bits (139), Expect = 8e-09, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 47/99 (47%), Gaps = 9/99 (9%) Query: 311 NNTTVFIGGLSSLVTEDELRA----YFQPFGT---IVYVKIPVGKCCGFVQYVDRLSAEA 363 N T+++ L+ + +++LR F +GT IV +K P + V + D +A Sbjct: 2 NQNTLYVNNLNDKINKNDLRTALYMLFSTYGTVVDIVALKTPKMRGQAHVVFFDPSAAAI 61 Query: 364 AIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQ 402 A+ ++ F +++ + S ++ ++++ + N + Sbjct: 62 AMKALKNFIFFGKEMKIQYAHS--KSKIIERIVAENDSR 98 Score = 52.2 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 11/90 (12%), Positives = 34/90 (37%), Gaps = 6/90 (6%) Query: 161 NNCSIFVGDLAPNVTESQLFE---LFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE 217 N +++V +L + ++ L + + Y + + +G V F + Sbjct: 2 NQNTLYVNNLNDKINKNDLRTALYMLFSTYGTVVDIVALKTP---KMRGQAHVVFFDPSA 58 Query: 218 QQLALSEMQGVFLNGRAIKVGPTSGQQQHV 247 +A+ ++ G+ +K+ + + + Sbjct: 59 AAIAMKALKNFIFFGKEMKIQYAHSKSKII 88 >1X5O-A nrPDB Length = 114 Score = 57.9 bits (138), Expect = 9e-09, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 39/87 (44%), Gaps = 2/87 (2%) Query: 148 SNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGY 207 S + + + ++++ +L ++ E +L + + + +I+ D +G S+G Sbjct: 11 SGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENM-LKPFGQVISTRILRD-SSGTSRGV 68 Query: 208 GFVKFTNSDEQQLALSEMQGVFLNGRA 234 GF + ++++ + + G F+ Sbjct: 69 GFARMESTEKCEAVIGHFNGKFIKTPP 95 Score = 52.2 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 37/101 (36%), Gaps = 16/101 (15%) Query: 278 SNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFG 337 S+G++ + +Q +Q P T ++I L + E EL +PFG Sbjct: 2 SSGSSGL-KASGVQAQMAKQQEQDP----------TNLYISNLPLSMDEQELENMLKPFG 50 Query: 338 TIVYVKIPVG-----KCCGFVQYVDRLSAEAAIAGMQGFPI 373 ++ +I + GF + EA I G I Sbjct: 51 QVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 91 Score = 29.4 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 32/96 (33%), Gaps = 15/96 (15%) Query: 33 NSSTSVLSLQGASNVSL---GTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWN 89 +S +S L G LY+ +L + D+ + + G+ I+ R++ + Sbjct: 2 SSGSSGLKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQV-ISTRILRD 60 Query: 90 NTLNNGSRSSMGPKNNQGYCFVDFPSSTHAANALLK 125 + ++G F S+ + Sbjct: 61 S-----------SGTSRGVGFARMESTEKCEAVIGH 85 >3JB9-a nrPDB Length = 354 Score = 57.6 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 2/83 (2%) Query: 304 LNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEA 363 + D ++F+ G+ + + ++R +F+ +G + V C FV + R SAE Sbjct: 203 MEPPKDKKIASLFLIGVEDELADYKIRKHFEQYGPLKSVVCSHRAKCAFVNFKTRSSAEI 262 Query: 364 AIAGM--QGFPIANSRVRLSWGR 384 A A I R+++ WG+ Sbjct: 263 AAAASPDGNVVIEGFRLKVQWGK 285 >2LA6-A nrPDB Length = 99 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 34/89 (38%), Gaps = 9/89 (10%) Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSH--------AKIVHDQVTGMSKGYGFVKF 212 +N +IFV L NVT + + F + + D+ TG KG V F Sbjct: 12 DNNTIFVQGLGENVTIESVADYF-KQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSF 70 Query: 213 TNSDEQQLALSEMQGVFLNGRAIKVGPTS 241 + + A+ G +G IKV + Sbjct: 71 DDPPSAKAAIDWFDGKEFSGNPIKVSFAT 99 Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 14/87 (16%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVK--------------IPVGKCCGFVQYV 356 +N T+F+ GL VT + + YF+ G I K K V + Sbjct: 12 DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 71 Query: 357 DRLSAEAAIAGMQGFPIANSRVRLSWG 383 D SA+AAI G + + +++S+ Sbjct: 72 DPPSAKAAIDWFDGKEFSGNPIKVSFA 98 >2CPD-A nrPDB Length = 99 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 9/74 (12%) Query: 165 IFVGDLAPNVTESQLFELFIN-RYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 ++V +L + +E + + F N + + K + D Y FV F+N ++ A+ Sbjct: 18 LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD--------YAFVHFSNREDAVEAMK 69 Query: 224 EMQGVFLNGRAIKV 237 + G L+G I+V Sbjct: 70 ALNGKVLDGSPIEV 83 Score = 48.7 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 11/84 (13%), Positives = 32/84 (38%) Query: 305 NHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAA 364 + T + +++ L +E+ + F ++ + FV + +R A A Sbjct: 8 DEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEA 67 Query: 365 IAGMQGFPIANSRVRLSWGRSAKQ 388 + + G + S + ++ + + Sbjct: 68 MKALNGKVLDGSPIEVTLAKPVDK 91 >5X3Y-A nrPDB Length = 96 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 32/75 (42%), Gaps = 5/75 (6%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLA-- 221 IFVG L+ N T + F ++ A ++ D+ T +G+GFV F + D + Sbjct: 6 KIFVGGLSVNTTVEDVKHYFE-QFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE 64 Query: 222 --LSEMQGVFLNGRA 234 E+ + + Sbjct: 65 IHFHEINNKMVECKK 79 Score = 44.1 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 25/56 (44%), Gaps = 6/56 (10%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKI------PVGKCCGFVQYVDRLSAEA 363 +F+GGLS T ++++ YF+ FG + + + GFV + E Sbjct: 6 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEK 61 Score = 36.8 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 38/110 (34%), Gaps = 14/110 (12%) Query: 50 GTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYC 109 G+ ++++G L V+ + G+ + + +M++ T N ++G+ Sbjct: 1 GSHMKKIFVGGLSVNTTVEDVKHYFEQFGKVD-DAMLMFDKTTNR----------HRGFG 49 Query: 110 FVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKS 159 FV F S + NK ++ A S +S Sbjct: 50 FVTFESEDIVEKVCEIH---FHEINNKMVECKKAQPKEVMSPTGSARGRS 96 >2MST-A nrPDB Length = 75 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 32/75 (42%), Gaps = 5/75 (6%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLA-- 221 IFVG L+ N T + F ++ A ++ D+ T +G+GFV F + D + Sbjct: 1 KIFVGGLSVNTTVEDVKHYFE-QFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE 59 Query: 222 --LSEMQGVFLNGRA 234 E+ + + Sbjct: 60 IHFHEINNKMVECKK 74 Score = 44.1 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 25/56 (44%), Gaps = 6/56 (10%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKI------PVGKCCGFVQYVDRLSAEA 363 +F+GGLS T ++++ YF+ FG + + + GFV + E Sbjct: 1 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEK 56 Score = 34.1 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 27/63 (42%), Gaps = 11/63 (17%) Query: 55 QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFP 114 ++++G L V+ + G+ + + +M++ T N ++G+ FV F Sbjct: 1 KIFVGGLSVNTTVEDVKHYFEQFGKVD-DAMLMFDKTTNR----------HRGFGFVTFE 49 Query: 115 SST 117 S Sbjct: 50 SED 52 >3JB9-Y nrPDB Length = 388 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 310 PNNTTVFIGGLSSLVTEDELRA-YFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGM 368 N T+++GG++ +E+ + +F +G I +++ + F+ Y++ +A+ A M Sbjct: 171 RQNYTLYVGGITPTDDIEEIVSRHFAEWGDIERIRVLNSRGIAFITYLNEANAQFAKEAM 230 Query: 369 QGFPI-ANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQ 406 + + + + W + A + N +++++ Sbjct: 231 AHQSLDHDECLNVRWATTDPNPA----SQARNQRRLEER 265 Score = 48.3 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 15/96 (15%), Positives = 32/96 (33%), Gaps = 7/96 (7%) Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 N +++VG + P ++ + +++ S+G F+ + N Q Sbjct: 172 QNYTLYVGGITPTDDIEEIVSRHFAEWGDIERIRVL------NSRGIAFITYLNEANAQF 225 Query: 221 ALSEMQGVFL-NGRAIKVGPTSGQQQHVSGNNDYNR 255 A M L + + V + S + R Sbjct: 226 AKEAMAHQSLDHDECLNVRWATTDPNPASQARNQRR 261 >2CPE-A nrPDB Length = 113 Score = 56.0 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 37/100 (37%), Gaps = 9/100 (9%) Query: 158 KSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAK--------IVHDQVTGMSKGYGF 209 + +N +I+V L +VT L + F + K I D+ TG KG Sbjct: 11 EDSDNSAIYVQGLNDSVTLDDLADFF-KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 69 Query: 210 VKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSG 249 V + + + A+ G G +KV + SG Sbjct: 70 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSG 109 >5O20-A nrPDB Length = 180 Score = 55.6 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 34/89 (38%), Gaps = 3/89 (3%) Query: 296 YPVQQQPSLNHFTDPN-NTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQ 354 PV +L + T+FIGG+ + E +L +PF + V + + FV+ Sbjct: 33 KPVSYDSTLPPDHIKVYSRTLFIGGVPLNMKEWDLANVLKPFAEVQSVILNNSRKHAFVK 92 Query: 355 YVDRLSAEAAIAGMQGFPIANSRVRLSWG 383 R AE + +R WG Sbjct: 93 VYSRHEAENVLQNFNKD--GALPLRTRWG 119 >5O1W-A nrPDB Length = 191 Score = 55.6 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 34/89 (38%), Gaps = 3/89 (3%) Query: 296 YPVQQQPSLNHFTDPN-NTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQ 354 PV +L + T+FIGG+ + E +L +PF + V + + FV+ Sbjct: 23 KPVSYDSTLPPDHIKVYSRTLFIGGVPLNMKEWDLANVLKPFAEVQSVILNNSRKHAFVK 82 Query: 355 YVDRLSAEAAIAGMQGFPIANSRVRLSWG 383 R AE + +R WG Sbjct: 83 VYSRHEAENVLQNFNKD--GALPLRTRWG 109 >2BZ2-A nrPDB Length = 121 Score = 55.6 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 51/110 (46%), Gaps = 13/110 (11%) Query: 275 SFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQ 334 + G++ F+R+ +P ++ P T+++ G +T LR F Sbjct: 13 GLVPRGSHMGPFRRSDS----FPERRAPR-------KGNTLYVYG--EDMTPTLLRGAFS 59 Query: 335 PFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGR 384 PFG I+ + + + C FV Y SA+ A+A + G + + +++++ R Sbjct: 60 PFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQVESVQLKVNIAR 109 Score = 52.2 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 36/103 (34%), Gaps = 9/103 (8%) Query: 146 SYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSK 205 + S++ +++V ++T + L F + + + + D + Sbjct: 23 PFRRSDSFPERRAPRKGNTLYVYG--EDMTPTLLRGAF-SPFGNIID--LSMDP----PR 73 Query: 206 GYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVS 248 FV + + A++E+ G + +KV Q + Sbjct: 74 NCAFVTYEKMESADQAVAELNGTQVESVQLKVNIARKQPMLDA 116 >2F9J-A nrPDB Length = 125 Score = 54.9 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 33/73 (45%), Gaps = 4/73 (5%) Query: 165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 + + +L +T +++++F +Y ++ + T +G +V + + + + A Sbjct: 21 LMIRNLPYKITAEEMYDIF-GKYGPIRQIRVGNTPET---RGTAYVVYEDIFDAKNACDH 76 Query: 225 MQGVFLNGRAIKV 237 + G + R + V Sbjct: 77 LSGFNVCNRYLVV 89 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 43/102 (42%), Gaps = 3/102 (2%) Query: 312 NTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPV---GKCCGFVQYVDRLSAEAAIAGM 368 N + I L +T +E+ F +G I +++ + +V Y D A+ A + Sbjct: 18 NRILMIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTAYVVYEDIFDAKNACDHL 77 Query: 369 QGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGL 410 GF + N + + + + + + L++ +++ G+ Sbjct: 78 SGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGI 119 >5YVG-X nrPDB Length = 528 Score = 54.1 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 39/114 (34%), Gaps = 9/114 (7%) Query: 141 NWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSH-------- 192 N + + + +N +IFV L NVT + + F + Sbjct: 265 NKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYF-KQIGIIKTNKKTGQPM 323 Query: 193 AKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQH 246 + D+ TG KG V F + + A+ G +G IKV + + Sbjct: 324 INLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADF 377 Score = 36.0 bits (81), Expect = 0.039, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 14/94 (14%) Query: 304 LNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVK--------------IPVGKC 349 + + +N T+F+ GL VT + + YF+ G I K K Sbjct: 278 DSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKG 337 Query: 350 CGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWG 383 V + D SA+AAI G + + +++S+ Sbjct: 338 EATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFA 371 >6GML-X nrPDB Length = 404 Score = 54.1 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 45/108 (41%), Gaps = 2/108 (1%) Query: 305 NHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAA 364 T+++ G +T LR F PFG I+ + + + C FV Y SA+ A Sbjct: 278 ERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQA 335 Query: 365 IAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGLQQ 412 +A + G + + +++++ R + SL VQ G + Sbjct: 336 VAELNGTQVESVQLKVNIARKQPMLDAATGKSVWGSLAVQNSPKGCHR 383 Score = 51.4 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 36/103 (34%), Gaps = 9/103 (8%) Query: 146 SYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSK 205 + S++ +++V ++T + L F + + + + D + Sbjct: 269 PFRRSDSFPERRAPRKGNTLYVYG--EDMTPTLLRGAF-SPFGNIID--LSMDP----PR 319 Query: 206 GYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVS 248 FV + + A++E+ G + +KV Q + Sbjct: 320 NCAFVTYEKMESADQAVAELNGTQVESVQLKVNIARKQPMLDA 362 >1X5P-A nrPDB Length = 97 Score = 51.8 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 2/80 (2%) Query: 305 NHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAA 364 T+++ G +T LR F PFG I+ + + + C FV Y SA+ A Sbjct: 8 ERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQA 65 Query: 365 IAGMQGFPIANSRVRLSWGR 384 +A + G + + +++++ R Sbjct: 66 VAELNGTQVESVQLKVNIAR 85 Score = 48.7 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 16/97 (16%), Positives = 34/97 (35%), Gaps = 9/97 (9%) Query: 153 SLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKF 212 S +++V ++T + L F + + + + D + FV + Sbjct: 6 SGERRAPRKGNTLYVYG--EDMTPTLLRGAF-SPFGNIID--LSMDP----PRNCAFVTY 56 Query: 213 TNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSG 249 + A++E+ G + +KV Q SG Sbjct: 57 EKMESADQAVAELNGTQVESVQLKVNIARKQPMLDSG 93 >6D6V-H nrPDB Length = 542 Score = 51.8 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 45/321 (14%), Positives = 99/321 (30%), Gaps = 45/321 (14%) Query: 91 TLNNGSRSSMGPKNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNS 150 G + KN++ Y + S L+++ + K+K++ Sbjct: 177 VSTYGIENQSQKKNHKNYKNQNATFSKKDLIHLIRDSLKESKIL--KVKMDSLKVKRRFP 234 Query: 151 NNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFV 210 N +K+ ++++ L P ++ L +F N + + + + + +G+ F+ Sbjct: 235 FNLEQALKNSKQRTLYIDFLPPKCSKQTLVSIFGNF--RIININLPLQKNSQLCQGFAFI 292 Query: 211 KFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFL 270 +F + +E AL + GQ R + + F Sbjct: 293 EFFSEEEANQALITKNSSIPKELILLTEKKIGQGSI--------RIITYKKWQEEKQSFK 344 Query: 271 SKGQSFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELR 330 ++ N NM R +F+ + + ++ L Sbjct: 345 ELSKNQNEQKNKNMNQSRKASDEFV-----------------------SIDVEIKQNCLI 381 Query: 331 AYFQ-PFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAKQT 389 P GT+ + + G+ Y D + + ++ + + T Sbjct: 382 KIINIPQGTLKAEVVLAVRHLGYEFYCDYIDENSNQINSNKISLSTQQ---------QNT 432 Query: 390 ALLQQAMLSNSLQVQQQQPGL 410 A + N+L Q Q P L Sbjct: 433 AQCSNIQIENNLIQQDQHPQL 453 Score = 37.1 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 13/87 (14%) Query: 47 VSLGTTGNQ-LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNN 105 +L + + LY+ L P K T+ I+ + NIN+ + N+ L Sbjct: 239 QALKNSKQRTLYIDFLPPKCSKQTLVSIFGNFRIININLPLQKNSQL------------C 286 Query: 106 QGYCFVDFPSSTHAANALLKNGMLIPN 132 QG+ F++F S A AL+ IP Sbjct: 287 QGFAFIEFFSEEEANQALITKNSSIPK 313 >6FEC-u nrPDB Length = 636 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 5/110 (4%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVT-GMSKGYGFVKFTNSDEQQLAL 222 + F+G+L +VTE + E F + S ++ + KG+G+ +F + D AL Sbjct: 122 TAFLGNLPYDVTEESIKEFFRGL--NISAVRLPREPSNPERLKGFGYAEFEDLDSLLSAL 179 Query: 223 SEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSK 272 S L R I+V Q + + R + +++ D+ + ++ Sbjct: 180 SL-NEESLGNRRIRVDVADQAQDKDRDDRSFGRD-RNRDSDKTDTDWRAR 227 Score = 32.5 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 9/81 (11%) Query: 314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG-------KCCGFVQYVDRLSAEAAIA 366 T F+G L VTE+ ++ +F+ I V++P K G+ ++ D S +A++ Sbjct: 122 TAFLGNLPYDVTEESIKEFFRGL-NISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALS 180 Query: 367 GMQGFPIANSRVRLSWGRSAK 387 + N R+R+ A+ Sbjct: 181 L-NEESLGNRRIRVDVADQAQ 200 >5LJ5-M nrPDB Length = 339 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 31/73 (42%), Gaps = 9/73 (12%) Query: 310 PNNTTVFIGGLSSLVT---------EDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLS 360 N T+++GG+ + E +R F G I ++ K CGFV++ + + Sbjct: 132 KKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYVESKNCGFVKFKYQAN 191 Query: 361 AEAAIAGMQGFPI 373 AE A M + Sbjct: 192 AEFAKEAMSNQTL 204 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 31/183 (16%), Positives = 53/183 (28%), Gaps = 27/183 (14%) Query: 160 GNNCSIFVGDLAPNVTESQLF--------ELFINRYASTSHAKIVHDQVTGMSKGYGFVK 211 N +++VG + + L +R + V SK GFVK Sbjct: 132 KKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYV------ESKNCGFVK 185 Query: 212 FTNSDEQQLALSEMQGVFL---NGRAIKVGPTSGQQQHVSGNNDYNRSSSSLN-NENVDS 267 F + A M L + + G V N+ ++ E + Sbjct: 186 FKYQANAEFAKEAMSNQTLLLPSDKEWD-DRREGTGLLVKWANEDPDPAAQKRLQEELKL 244 Query: 268 RFLSKGQSFLSNGNNNMG----FKRNHMSQFIYPVQQ----QPSLNHFTDPNNTTVFIGG 319 L+ ++N N+ G K N +P + L + + FI Sbjct: 245 ESLNMMVHLINNNTNSAGTEVNNKNNERLDRTFPEASVDNVKKRLLPLDNGMESDDFIEK 304 Query: 320 LSS 322 L Sbjct: 305 LKK 307 >3U1M-A nrPDB Length = 240 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 31/73 (42%), Gaps = 9/73 (12%) Query: 310 PNNTTVFIGGLSSLVT---------EDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLS 360 N T+++GG+ + E +R F G I ++ K CGFV++ + + Sbjct: 132 KKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYVESKNCGFVKFKYQAN 191 Query: 361 AEAAIAGMQGFPI 373 AE A M + Sbjct: 192 AEFAKEAMSNQTL 204 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 24/79 (30%), Gaps = 14/79 (17%) Query: 160 GNNCSIFVGDLAPNVTESQLF--------ELFINRYASTSHAKIVHDQVTGMSKGYGFVK 211 N +++VG + + L +R + V SK GFVK Sbjct: 132 KKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYV------ESKNCGFVK 185 Query: 212 FTNSDEQQLALSEMQGVFL 230 F + A M L Sbjct: 186 FKYQANAEFAKEAMSNQTL 204 >3Q2T-C nrPDB Length = 229 Score = 48.7 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 41/102 (40%), Gaps = 3/102 (2%) Query: 159 SGNNCSIFVGDLAPNVTESQLFELFIN-RYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE 217 +G ++++G+L T+ L E + K ++ G SKG+ V + Sbjct: 65 TGKRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEAS 124 Query: 218 QQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSS 259 + + + L+G+ V P +Q +S +R ++ Sbjct: 125 SKKLMDLLPKRELHGQNPVVTPV--NKQFLSQFEMQSRKTTQ 164 >2LXI-A nrPDB Length = 91 Score = 47.9 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 9/56 (16%), Positives = 24/56 (42%) Query: 169 DLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 L TE + + +++ ++ +G S+G+ FV+F++ + + Sbjct: 8 MLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEA 63 Score = 39.1 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 33/85 (38%), Gaps = 11/85 (12%) Query: 61 LDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAA 120 L ++ +R S G VR+M N + ++G+ FV+F A Sbjct: 9 LPQAATEDDIRGQLQSHGVQAREVRLMRNKSSG----------QSRGFAFVEFSHLQDAT 58 Query: 121 NALLKNGMLIPNFPNKKLKLNWATS 145 + N + N +K+ ++++ Sbjct: 59 RWMEANQHSL-NILGQKVSMHYSDP 82 Score = 34.8 bits (78), Expect = 0.083, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 26/76 (34%), Gaps = 8/76 (10%) Query: 315 VFIGGLSSLVTEDELRAYFQPFG-TIVYVKIPVGK------CCGFVQYVDRLSAEAAIAG 367 V + L TED++R Q G V++ K FV++ A + Sbjct: 4 VMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEA 63 Query: 368 -MQGFPIANSRVRLSW 382 I +V + + Sbjct: 64 NQHSLNILGQKVSMHY 79 >3P6Y-C nrPDB Length = 90 Score = 46.0 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 31/77 (40%), Gaps = 1/77 (1%) Query: 165 IFVGDLAPNVTESQLFELFIN-RYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 +++G+L T+ L E + K ++ G SKG+ V + + + Sbjct: 4 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 63 Query: 224 EMQGVFLNGRAIKVGPT 240 + L+G+ V P+ Sbjct: 64 LLPKRELHGQNPVVTPS 80 >3N9U-C nrPDB Length = 156 Score = 45.6 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 36/100 (36%), Gaps = 3/100 (3%) Query: 161 NNCSIFVGDLAPNVTESQLFELFINRYA--STSHAKIVHDQVTGMSKGYGFVKFTNSDEQ 218 +++VG + T+ QL ++ I K ++ G SKGY V + + Sbjct: 54 RRAAVYVGSFSWWTTDQQLIQV-IRSIGVYDVVELKFAENRANGQSKGYAEVVVASENSV 112 Query: 219 QLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSS 258 L + G LNG + V P + Q R Sbjct: 113 HKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECV 152 >2LKZ-A nrPDB Length = 95 Score = 45.6 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 43/85 (50%), Gaps = 7/85 (8%) Query: 164 SIFVGDLAPNVTESQLFELFINRYAS--TSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLA 221 +I + ++AP+ + ++ YAS ++ +++ D+ T ++G+ FV+ +++ + Sbjct: 11 TIILRNIAPHTVVDSIMTA-LSPYASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQL 69 Query: 222 LSEMQG----VFLNGRAIKVGPTSG 242 L +Q + ++G+ I V Sbjct: 70 LQILQSLHPPLKIDGKTIGVDFAKS 94 Score = 32.1 bits (71), Expect = 0.59, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 34/89 (38%), Gaps = 13/89 (14%) Query: 60 DLDPTWDKNTVRQIWASLGEANIN-VRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTH 118 ++ P +++ + +N +R++ + N+G+ FV S+ Sbjct: 16 NIAPHTVVDSIMTALSPYASLAVNNIRLIKDKQTQ----------QNRGFAFVQLSSAMD 65 Query: 119 AANALLKNGMLIPNFP--NKKLKLNWATS 145 A+ L L P K + +++A S Sbjct: 66 ASQLLQILQSLHPPLKIDGKTIGVDFAKS 94 >6FYY-p nrPDB Length = 763 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 16/96 (16%), Positives = 37/96 (38%), Gaps = 14/96 (14%) Query: 176 ESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAI 235 + L LF ++ + + D+ TG +KG+ FV+ + ++ + + G L+ + Sbjct: 96 KKALTSLF-SKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLK-- 152 Query: 236 KVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLS 271 + Y N+++ D+ F Sbjct: 153 ----HRLFLYTMKDVERY-------NSDDFDTEFRE 177 >2RUG-A nrPDB Length = 114 Score = 45.2 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 27/68 (39%), Gaps = 13/68 (19%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHD---QVTGMS----KGYGFVKFTNSD 216 +FVG L P++ E ++ F R+ +V D + S KGY F+ F Sbjct: 10 KVFVGGLPPDIDEDEITASF-RRFGP-----LVVDWPHKAESKSYFPPKGYAFLLFQEES 63 Query: 217 EQQLALSE 224 Q + Sbjct: 64 SVQALIDA 71 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 26/63 (41%), Gaps = 8/63 (12%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTI--------VYVKIPVGKCCGFVQYVDRLSAEAA 364 VF+GGL + EDE+ A F+ FG + K F+ + + S +A Sbjct: 9 RKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQAL 68 Query: 365 IAG 367 I Sbjct: 69 IDA 71 Score = 33.3 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 36/98 (36%), Gaps = 18/98 (18%) Query: 54 NQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDF 113 ++++G L P D++ + + G ++ + S+S PK GY F+ F Sbjct: 9 RKVFVGGLPPDIDEDEITASFRRFG------PLVVDWPHKAESKSYFPPK---GYAFLLF 59 Query: 114 PSSTH---------AANALLKNGMLIPNFPNKKLKLNW 142 + + L + P +K +++ Sbjct: 60 QEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRP 97 >2KVI-A nrPDB Length = 96 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 18/97 (18%) Query: 164 SIFVGDLA-PNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 +F+G+L NV++ LF +F + Y I +GF++F N + A+ Sbjct: 12 RLFIGNLPLKNVSKEDLFRIF-SPYGHIMQINI--------KNAFGFIQFDNPQSVRDAI 62 Query: 223 ----SEMQ-GVFLNGRAIKVGPTSGQQQHVSGNNDYN 254 EM G L ++V ++ + Q G++ N Sbjct: 63 ECESQEMNFGKKL---ILEVSSSNARPQFDHGDHGTN 96 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 3/57 (5%) Query: 310 PNNTTVFIGGLS-SLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAI 365 P + +FIG L V++++L F P+G I+ + I GF+Q+ + S AI Sbjct: 8 PPKSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINIKN--AFGFIQFDNPQSVRDAI 62 >3NS5-A nrPDB Length = 91 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 28/58 (48%), Gaps = 1/58 (1%) Query: 176 ESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGR 233 + L LF ++ + + D+ TG +KG+ FV+ + ++ + + G L+ + Sbjct: 26 KKALTSLF-SKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLK 82 >2XNQ-A nrPDB Length = 97 Score = 44.1 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 15/84 (17%) Query: 153 SLNNVKSGNNCSIFVGDLA-PNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVK 211 L S +F+G+L NV++ LF +F + Y I +GF++ Sbjct: 13 GLVPRGSHMKSRLFIGNLPLKNVSKEDLFRIF-SPYGHIMQINI--------KNAFGFIQ 63 Query: 212 FTNSDEQQLAL----SEMQ-GVFL 230 F N + A+ EM G L Sbjct: 64 FDNPQSVRDAIECESQEMNFGKKL 87 Score = 43.3 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 7/65 (10%) Query: 302 PSLNHFTDPNNTTVFIGGLS-SLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLS 360 P +H + +FIG L V++++L F P+G I+ + I GF+Q+ + S Sbjct: 16 PRGSHM----KSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINIKN--AFGFIQFDNPQS 69 Query: 361 AEAAI 365 AI Sbjct: 70 VRDAI 74 >2CPI-A nrPDB Length = 111 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 30/81 (37%), Gaps = 12/81 (14%) Query: 315 VFIGGLSSLVTEDELR---AYFQPFGTIVYVKIPVGKCCG---------FVQYVDRLSAE 362 VF+ GLS + + E+ YF FG I V I +V Y+ A Sbjct: 18 VFVVGLSQRLADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDAL 77 Query: 363 AAIAGMQGFPIANSRVRLSWG 383 AI + + ++ S G Sbjct: 78 RAIQCVNNVVVDGRTLKASLG 98 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 34/77 (44%), Gaps = 5/77 (6%) Query: 165 IFVGDLAPNVTESQLFE--LFINRYASTSHAKIVHDQVTGMSKG---YGFVKFTNSDEQQ 219 +FV L+ + + ++ + + ++ I + S+G +V + S++ Sbjct: 18 VFVVGLSQRLADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDAL 77 Query: 220 LALSEMQGVFLNGRAIK 236 A+ + V ++GR +K Sbjct: 78 RAIQCVNNVVVDGRTLK 94 >2M2B-A nrPDB Length = 131 Score = 42.1 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 50/94 (53%), Gaps = 4/94 (4%) Query: 162 NCSIFVGDLAPNVT-ESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 N +I + +L P+ T +S L L S+S+ +++ D+ T +++G+ F++ + + QL Sbjct: 23 NDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIEAAQL 82 Query: 221 --ALSEMQ-GVFLNGRAIKVGPTSGQQQHVSGNN 251 L + + ++G+ I V G ++ ++ N Sbjct: 83 LQILQALHPPLTIDGKTINVEFAKGSKRDMASNE 116 >5OPT-h nrPDB Length = 257 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 32/97 (32%), Gaps = 10/97 (10%) Query: 160 GNNCSIFVGDLAP-NVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQ 218 N+ +FV + + T+ Q+ ELF + Y +V Sbjct: 154 ANSSVVFVSPIFRASTTKKQILELFSGM--KVLRLRTYR-------NNYAYVYLDTPAAA 204 Query: 219 QLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNR 255 Q A+ E G G+ ++V ++ + R Sbjct: 205 QRAVKEKNGAEFRGKQLRVALSTRSLAKDRARAERAR 241 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 21/206 (10%), Positives = 49/206 (23%), Gaps = 66/206 (32%) Query: 207 YGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVD 266 Y + F N+ + A+ G G + V P + Sbjct: 111 YAIIFFENAAAVKKAIDLFNGKEFMGNVLSVVPAKTTPKPDPHA---------------- 154 Query: 267 SRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTE 326 N F+ P+ + + T +F G Sbjct: 155 ----------------------NSSVVFVSPIFRAST----TKKQILELFSGM------- 181 Query: 327 DELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRL-----S 381 ++ ++ +V +A+ A+ G ++R+ S Sbjct: 182 -----------KVLRLRTYRN-NYAYVYLDTPAAAQRAVKEKNGAEFRGKQLRVALSTRS 229 Query: 382 WGRSAKQTALLQQAMLSNSLQVQQQQ 407 + + + M + ++ Sbjct: 230 LAKDRARAERARLLMAAQKFNKRKNH 255 >5WSG-X nrPDB Length = 111 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 28/83 (33%), Gaps = 7/83 (8%) Query: 164 SIFVGDLAPNVTESQLFE---LFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 +++V L + +L L + + +G F+ D+ L Sbjct: 29 TLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSM----NFKKQRGQAFITMRTIDQASL 84 Query: 221 ALSEMQGVFLNGRAIKVGPTSGQ 243 A + G G+ +KV + + Sbjct: 85 AQISLNGERFFGKPLKVEFSKSE 107 >5WU6-A nrPDB Length = 485 Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 8/92 (8%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 S+FV +V +QL E F+ + A +V D+ G+ + V+ + + A+ Sbjct: 5 SVFVSGFPRDVDSAQLSEYFLA-FGPV--ASVVMDKDKGV---FAIVEMGDVG-AREAVL 57 Query: 224 EMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNR 255 L G ++V P Q++ S + + Sbjct: 58 SQSQHSLGGHRLRVRP-REQKEFQSPASKSPK 88 Score = 38.3 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 28/71 (39%), Gaps = 2/71 (2%) Query: 311 NNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKC-CGFVQYVDRLSAEAAIAGMQ 369 +VF+ G V +L YF FG + V + K V+ D + A A+ Sbjct: 2 GLRSVFVSGFPRDVDSAQLSEYFLAFGPVASVVMDKDKGVFAIVEMGD-VGAREAVLSQS 60 Query: 370 GFPIANSRVRL 380 + R+R+ Sbjct: 61 QHSLGGHRLRV 71 >2MKK-A nrPDB Length = 213 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 24/186 (12%), Positives = 51/186 (27%), Gaps = 24/186 (12%) Query: 53 GNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVD 112 ++++G + + + + G ++ G +GY ++ Sbjct: 18 SCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWP---------GKDGKHPRCPPKGYVYLV 68 Query: 113 FPSSTHA---ANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNC------ 163 F A + + K++ + N Sbjct: 69 FELEKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQR 128 Query: 164 -----SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQ 218 ++FVG L + L + + + +A I D+ G G V F N Sbjct: 129 LDPSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHK-YPIGSGRVTFNNQRSY 187 Query: 219 QLALSE 224 A+S Sbjct: 188 LKAVSA 193 Score = 32.1 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 16/106 (15%), Positives = 39/106 (36%), Gaps = 8/106 (7%) Query: 300 QQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG--------KCCG 351 Q P N+ + VF+GG+ +TE L F+ FG++ K Sbjct: 6 QLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGYV 65 Query: 352 FVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAML 397 ++ + S + + P++ + + + + + ++ + Sbjct: 66 YLVFELEKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQV 111 Score = 31.4 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 28/79 (35%), Gaps = 3/79 (3%) Query: 148 SNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGM--SK 205 S N +C +F+G + ++TE+ L F + S S D K Sbjct: 4 SGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTF-RVFGSLSVEWPGKDGKHPRCPPK 62 Query: 206 GYGFVKFTNSDEQQLALSE 224 GY ++ F + L Sbjct: 63 GYVYLVFELEKSVRSLLQA 81 >5K1H-B nrPDB Length = 576 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 13/106 (12%), Positives = 46/106 (43%), Gaps = 10/106 (9%) Query: 156 NVKSGNNCSIFVGDLAP------NVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGF 209 G + I V ++ ++ + ++F +++ ++ + G +KGY F Sbjct: 9 QEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIF-SKFGKITNDFYP--EEDGKTKGYIF 65 Query: 210 VKFTNSDEQQLALSEMQGVFLNGR-AIKVGPTSGQQQHVSGNNDYN 254 +++ + A+ G L+ + +V + ++++ +++++ Sbjct: 66 LEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWD 111 >2E5G-A nrPDB Length = 94 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 164 SIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALS 223 S+FV V +QL E F+ + A +V D+ G+ + V+ + + A+ Sbjct: 10 SVFVSGFPRGVDSAQLSEYFLA-FGPV--ASVVMDKDKGV---FAIVEMGDVG-AREAVL 62 Query: 224 EMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNR 255 L G ++V P Q++ S + + Sbjct: 63 SQSQHSLGGHRLRVRP-REQKEFQSPASKSPK 93 Score = 38.7 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 28/69 (40%), Gaps = 2/69 (2%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKC-CGFVQYVDRLSAEAAIAGMQGF 371 +VF+ G V +L YF FG + V + K V+ D + A A+ Sbjct: 9 RSVFVSGFPRGVDSAQLSEYFLAFGPVASVVMDKDKGVFAIVEMGD-VGAREAVLSQSQH 67 Query: 372 PIANSRVRL 380 + R+R+ Sbjct: 68 SLGGHRLRV 76 >2NLW-A nrPDB Length = 105 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 12/84 (14%), Positives = 34/84 (40%), Gaps = 9/84 (10%) Query: 156 NVKSGNNCSIFVGDLAP------NVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGF 209 G + I V ++ ++ + ++F +++ ++ + G +KGY F Sbjct: 9 QEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIF-SKFGKITNDFYP--EEDGKTKGYIF 65 Query: 210 VKFTNSDEQQLALSEMQGVFLNGR 233 +++ + A+ G L+ + Sbjct: 66 LEYASPAHAVDAVKNADGYKLDKQ 89 >2KRB-A nrPDB Length = 81 Score = 38.3 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 33/78 (42%), Gaps = 9/78 (11%) Query: 162 NCSIFVGDLAP------NVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNS 215 + I V ++ ++ + ++F +++ ++ + G +KGY F+++ + Sbjct: 1 DSVIVVDNVPQVGPDRLEKLKNVIHKIF-SKFGKITNDFYP--EEDGKTKGYIFLEYASP 57 Query: 216 DEQQLALSEMQGVFLNGR 233 A+ G L+ + Sbjct: 58 AHAVDAVKNADGYKLDKQ 75 >5OSG-h nrPDB Length = 235 Score = 38.3 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 21/148 (14%), Positives = 50/148 (33%), Gaps = 19/148 (12%) Query: 106 QGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSI 165 Q Y V F +S A+ + + + A +S + N+ + Sbjct: 88 QRYALVFFENSAAVKKAIDL--FNEKEVLGQTVLVVPAKASPKPDAHE-------NSSCV 138 Query: 166 FVGDL-APNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSE 224 FV + P+ T++Q+ ELF ++ + + + + + + E Sbjct: 139 FVSPIFRPSTTKAQVMELFAGV--KVQRLRMYR-------QNFAYAYLDSPAAAKKFVEE 189 Query: 225 MQGVFLNGRAIKVGPTSGQQQHVSGNND 252 G G ++V ++ + + + Sbjct: 190 KNGTAFRGHTLRVALSARSLEKLRARQE 217 Score = 32.1 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 10/68 (14%), Positives = 21/68 (30%), Gaps = 7/68 (10%) Query: 184 INRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQ 243 + ++ + Y V F NS + A+ + G+ + V P Sbjct: 74 FSAAGKVVKVQLRRQR-------YALVFFENSAAVKKAIDLFNEKEVLGQTVLVVPAKAS 126 Query: 244 QQHVSGNN 251 + + N Sbjct: 127 PKPDAHEN 134 Score = 30.2 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 8/53 (15%), Positives = 19/53 (35%), Gaps = 1/53 (1%) Query: 328 ELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRL 380 + F G +V V++ + V + + + + AI + V + Sbjct: 69 DATNVFSAAGKVVKVQL-RRQRYALVFFENSAAVKKAIDLFNEKEVLGQTVLV 120 >1JMT-A nrPDB Length = 104 Score = 37.9 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 25/59 (42%), Gaps = 1/59 (1%) Query: 177 SQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAI 235 ++F +Y + D + G +VKF ++ + A+ ++ + NG+ I Sbjct: 41 EEVFTEMEEKYGEVEEMNVC-DNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPI 98 Score = 34.1 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 6/62 (9%), Positives = 18/62 (29%), Gaps = 5/62 (8%) Query: 322 SLVTEDELRAYFQPFGTIVYVKIPVGKC-----CGFVQYVDRLSAEAAIAGMQGFPIANS 376 E+ + +G + + + +V++ AE A+ + Sbjct: 37 DEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQ 96 Query: 377 RV 378 + Sbjct: 97 PI 98 >4YH8-A nrPDB Length = 216 Score = 37.5 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 27/76 (35%), Gaps = 11/76 (14%) Query: 171 APNVTESQLFELF----------INRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 T+ +L E F ++Y + D V G +V+F + Q Sbjct: 61 GKKFTQRELAEQFDAFYEDMFCEFSKYGEVEQLVVC-DNVGDHLVGNVYVRFKYEESAQN 119 Query: 221 ALSEMQGVFLNGRAIK 236 A+ ++ + + R + Sbjct: 120 AIDDLNSRWYSQRPVY 135 Score = 32.5 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 32/99 (32%), Gaps = 10/99 (10%) Query: 287 KRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTE--DELRAYFQPFGTIVYVKI 344 K N + P + N +PN L+ +++ F +G + + + Sbjct: 39 KPNFSQTILCPNMYK---NPIHEPNGKKFTQRELAEQFDAFYEDMFCEFSKYGEVEQLVV 95 Query: 345 PVGKC-----CGFVQYVDRLSAEAAIAGMQGFPIANSRV 378 +V++ SA+ AI + + V Sbjct: 96 CDNVGDHLVGNVYVRFKYEESAQNAIDDLNSRWYSQRPV 134 >2AD9-A nrPDB Length = 119 Score = 37.1 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 5/70 (7%) Query: 302 PSLNHFTDPNN-----TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYV 356 P +H D + + I L VTE E+ + PFG + + + GK F++ Sbjct: 16 PRGSHMGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMN 75 Query: 357 DRLSAEAAIA 366 +A + Sbjct: 76 TEEAANTMVN 85 >3S8S-A nrPDB Length = 110 Score = 36.8 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 29/83 (34%), Gaps = 1/83 (1%) Query: 170 LAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVF 229 L NV E+ L ++ +Y +I+ T G V FT++ + + + Sbjct: 14 LNDNVRETFLKDM-CRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTS 72 Query: 230 LNGRAIKVGPTSGQQQHVSGNND 252 + G I QQ + Sbjct: 73 VMGNIIHAQLDIKGQQRMKYYEL 95 >5Y88-M nrPDB Length = 364 Score = 35.6 bits (80), Expect = 0.049, Method: Composition-based stats. Identities = 22/169 (13%), Positives = 55/169 (32%), Gaps = 18/169 (10%) Query: 224 EMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNN 283 ++ V L G I P+ N R++S + S L K + L Sbjct: 114 SLKNVKLGGAQITSDPSEADNIVDKLKNILLRATS-----DGPSTPLIKNTTALYKNEKG 168 Query: 284 MGFKRNHMS----QFIYPVQQQPSLNHF-TDPNNTTVFIGGLSSLVTEDELRAYFQPF-- 336 +N + +++ P F +P+ + F+ + + + E ++ Sbjct: 169 ANEVKNLEKYASVDISHILKKLPLNESFLKNPSTKSFFLYNIDASIPEWKITDTVSQLLG 228 Query: 337 ------GTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVR 379 G + + + CG +++ E ++ + + ++ Sbjct: 229 IKKWKDGNSLSLIVNHKAKCGGLRFQSSELGERFVSKISETLVTPKGLK 277 >2MQN-A nrPDB Length = 216 Score = 34.8 bits (78), Expect = 0.081, Method: Composition-based stats. Identities = 19/136 (13%), Positives = 46/136 (33%), Gaps = 10/136 (7%) Query: 160 GNNCSIFVGDLAP-NVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQ 218 ++ + V L + ++F +F Y + K + + G V+ + Sbjct: 6 ADSPVLMVYGLDQSKMNCDRVFNVFC-LYGNVEKVKFMKSKP-----GAAMVEMADGYAV 59 Query: 219 QLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLS 278 A++ + F+ G+ + V +Q + Y S + ++ S + S Sbjct: 60 DRAITHLNNNFMFGQKMNV--CVSKQPAIMPGQSYGLEDGSCSYKD-FSESRNNRFSTPE 116 Query: 279 NGNNNMGFKRNHMSQF 294 N +++ F Sbjct: 117 QAAKNRIQHPSNVLHF 132 >5Z9X-A nrPDB Length = 409 Score = 34.1 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 16/115 (13%), Positives = 38/115 (33%), Gaps = 18/115 (15%) Query: 118 HAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTES 177 A+ A+ ++ + +K + + +F+ + NV Sbjct: 283 DASAAMKLALAVVEKRVDTTIKPSK-------------EMLEVEKAKLFLHKIPNNVPSE 329 Query: 178 QLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNG 232 +L ++ ++ T K Q G F F +S++ A + G+ + Sbjct: 330 ELEQVLSGKF--TLDVKQAKTQ--GRYY-CAFALFHSSEDADQAFEHIDGIEMTD 379 >2B7M-A nrPDB Length = 566 Score = 34.1 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 38/271 (14%), Positives = 85/271 (31%), Gaps = 23/271 (8%) Query: 123 LLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNV--TESQLF 180 +L+ G+ ++ + + N + + + L + +E+QL Sbjct: 30 ILQKGINQVGLKQYTQVVHKLDDMLEDIQSGQANREENSEFHGILTHLEQLIKRSEAQLR 89 Query: 181 ELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLA--LSEMQGVFLNGRAIKVG 238 FI+ S D ++K F + + L+ L G G I+ Sbjct: 90 VYFISILNSIKPF----DPQINITKKMPFPYYEDQQLGALSWILDYFHGNS-EGSIIQ-D 143 Query: 239 PTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNM-GFKRNHMSQFIYP 297 G++ + + + KG S +++ + GF N S + Sbjct: 144 ILVGERSKLILKCMAFLEPFAKEISTAKNAPYEKGSSGMNSYTEALLGFIANEKS-LVDD 202 Query: 298 VQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVD 357 + Q + + + S + + AY + FG + + + GF + Sbjct: 203 LYSQYTESKPH-----------VLSQILSPLISAYAKLFGANLKIVRSNLENFGFFSFEL 251 Query: 358 RLSAEAAIAGMQGFPIANSRVRLSWGRSAKQ 388 S ++G + N + + +Q Sbjct: 252 VESINDVKKSLRGKELQNYNLLQDCTQEVRQ 282 >3DXB-A nrPDB Length = 222 Score = 33.7 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 30/72 (41%), Gaps = 12/72 (16%) Query: 169 DLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYG-----FVKFTNSDEQQLALS 223 DL VTE ++ + + I++ + G + FV+F+ + E A+ Sbjct: 141 DLEGEVTEE------CGKFGAVNRV-IIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQ 193 Query: 224 EMQGVFLNGRAI 235 + G + GR + Sbjct: 194 ALNGRWFAGRKV 205 Score = 33.3 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 22/71 (30%), Gaps = 13/71 (18%) Query: 321 SSLVTED---ELRAYFQPFGTIVYVKIPVGKCCG----------FVQYVDRLSAEAAIAG 367 + +D E+ FG + V I K FV++ AI Sbjct: 135 PKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQA 194 Query: 368 MQGFPIANSRV 378 + G A +V Sbjct: 195 LNGRWFAGRKV 205 >2PEH-A nrPDB Length = 105 Score = 33.3 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 8/44 (18%), Positives = 19/44 (43%) Query: 209 FVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNND 252 F++F + A+ ++ G + GR +K + + V + Sbjct: 60 FLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAE 103 >4NOX-A nrPDB Length = 746 Score = 32.9 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 200 VTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGR-AIKVG 238 GMS + FV++++ E A+ ++ V L+ + ++V Sbjct: 85 DDGMSLRFAFVEYSSPAEASAAVRQLDYVPLDKKHTLRVN 124 >2W9X-A nrPDB Length = 366 Score = 32.9 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 20/133 (15%), Positives = 45/133 (33%), Gaps = 9/133 (6%) Query: 109 CFVDFPSSTHAAN--ALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKS---GNNC 163 VD+P + A + + + + + S + G++ Sbjct: 93 GKVDYPVESLAPGKHRVRLEKLTETQSTSGRFLGFYTDPSAKPLALPKRKRQIEFIGDSF 152 Query: 164 SIFVGDLAP--NVTESQLFELFINR--YASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQ 219 ++ G+ +P T+ +LF+ ++ + + D S G+G V+ N Sbjct: 153 TVGYGNTSPSRECTDEELFKTTNSQMAFGPLTAKAFDADYQINASSGFGIVRNYNGTSPD 212 Query: 220 LALSEMQGVFLNG 232 +L + LN Sbjct: 213 KSLLSLYPYTLNN 225 >3HBX-A nrPDB Length = 502 Score = 32.5 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 47/349 (13%), Positives = 103/349 (29%), Gaps = 45/349 (12%) Query: 14 NLVRNDSSPYTNTISSETNNSSTSVLS--LQGASNV----SLGTTGNQLYMG-DLDPTWD 66 N V D P T + + N + + L+ A ++G++ + G W Sbjct: 83 NYVDMDEYPVTTELQNRCVNMIAHLFNAPLEEAETAVGVGTVGSSEAIMLAGLAFKRKWQ 142 Query: 67 KNTVRQ---IWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAANAL 123 + + NV++ W K ++GY +V A + + Sbjct: 143 NKRKAEGKPVDKPNIVTGANVQVCWEKFARYFEVELKEVKLSEGY-YV--MDPQQAVDMV 199 Query: 124 LKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFV-----GDLAPNVTESQ 178 +N + + L + N N ++G + I V G +AP + Sbjct: 200 DENTICVAAILGSTLNGEFEDVKLLNDLLVEKNKETGWDTPIHVDAASGGFIAPFLYPEL 259 Query: 179 LFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDE-QQLALSEMQGVFLNGRAIKV 237 ++ R + + + G G+V + N ++ + + + + + + Sbjct: 260 EWDF---RLPLVKSINVSGHKYGLVYAGIGWVIWRNKEDLPEELIFHINYLGADQPTFTL 316 Query: 238 GPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYP 297 + G Q ++ R G N+ + Sbjct: 317 NFSKGSSQVIAQYYQLIR--------------------LGHEGYRNVMENCRENMIVLRE 356 Query: 298 -VQQQPSLNHFTDPNNTTVFIGGLSSLV--TEDELRAYFQPFGTIVYVK 343 +++ N + + L TE E+ + +G IV Sbjct: 357 GLEKTERFNIVSKDEGVPLVAFSLKDSSCHTEFEISDMLRRYGWIVPAY 405 >2VOD-A nrPDB Length = 193 Score = 32.5 bits (72), Expect = 0.51, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 34/82 (41%), Gaps = 6/82 (7%) Query: 287 KRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPV 346 K P+ + + + D N +V+I G + T D+++ + + G ++ +++ Sbjct: 85 KTKIRRSPSKPLPEV-TDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRR 143 Query: 347 G-----KCCGFVQYVDRLSAEA 363 K FV + SA+ Sbjct: 144 TLHKAFKGSIFVVFDSIESAKK 165 >2DNR-A nrPDB Length = 91 Score = 31.7 bits (70), Expect = 0.71, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Query: 327 DELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLS 381 DEL F FG ++ ++ K +V +++ SA + + G + N + ++ Sbjct: 30 DELLQQFASFGEVILIRFVEDKM--WVTFLEGSSALN-VLSLNGKELLNRTITIA 81 Score = 31.7 bits (70), Expect = 0.77, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 23/67 (34%), Gaps = 10/67 (14%) Query: 177 SQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIK 236 +L + F + + + V D++ +V F LS + G L R I Sbjct: 30 DELLQQFAS-FGEVILIRFVEDKM--------WVTFLEGSSALNVLS-LNGKELLNRTIT 79 Query: 237 VGPTSGQ 243 + S Sbjct: 80 IALKSPS 86 >3I6D-A nrPDB Length = 470 Score = 31.0 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 41/144 (28%), Gaps = 27/144 (18%) Query: 271 SKGQSFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELR 330 +K F+S G ++ K FI P + D + F + V E+ + Sbjct: 116 TKIAPFVSTGLFSLSGKARAAMDFILP-----ASKTKDDQSLGEFFRRRVGDEVVENLIE 170 Query: 331 AYFQPF--GTIVYVKIPVGKCCGFVQYV-DRLSAEAAIAGMQGFPIANSRVRLSWGRSAK 387 G I + + F Q+ + I GM+ S Sbjct: 171 PLLSGIYAGDIDKLSLMST----FPQFYQTEQKHRSLILGMKKTRPQGS----------- 215 Query: 388 QTALLQQAMLSNSLQVQQQQPGLQ 411 QQ Q Q GLQ Sbjct: 216 ----GQQLTAKKQGQFQTLSTGLQ 235 >2DIU-A nrPDB Length = 96 Score = 30.2 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 30/71 (42%), Gaps = 1/71 (1%) Query: 313 TTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCC-GFVQYVDRLSAEAAIAGMQGF 371 T +++ L + + + K+ C ++++++ SAE A M+ Sbjct: 10 TLLYVYNLPANKDGKSVSNRLRRLSDNCGGKVLSITGCSAILRFINQDSAERAQKRMENE 69 Query: 372 PIANSRVRLSW 382 + +R+ +S+ Sbjct: 70 DVFGNRIIVSF 80 >1S79-A nrPDB Length = 103 Score = 29.8 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 28/62 (45%), Gaps = 5/62 (8%) Query: 307 FTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVG-----KCCGFVQYVDRLSA 361 D N +V+I G + T D+++ + + G ++ +++ K FV + SA Sbjct: 6 KNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESA 65 Query: 362 EA 363 + Sbjct: 66 KK 67 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.119 0.293 Lambda K H 0.267 0.0373 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,574,361 Number of Sequences: 36641 Number of extensions: 604114 Number of successful extensions: 2172 Number of sequences better than 10.0: 145 Number of HSP's better than 10.0 without gapping: 204 Number of HSP's successfully gapped in prelim test: 46 Number of HSP's that attempted gapping in prelim test: 1358 Number of HSP's gapped (non-prelim): 571 length of query: 523 length of database: 10,336,785 effective HSP length: 102 effective length of query: 421 effective length of database: 6,599,403 effective search space: 2778348663 effective search space used: 2778348663 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 61 (28.2 bits)