BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P9WQH7 (548 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2A7S-A nrPDB 1124 0.0 3IBB-A nrPDB 728 0.0 5INF-A nrPDB 566 e-161 3N6R-B nrPDB 561 e-160 1X0U-A nrPDB 527 e-150 1ON3-A nrPDB 502 e-142 4L6W-A nrPDB 347 6e-96 4Q0G-A nrPDB 255 4e-68 3U9S-B nrPDB 237 1e-62 5IKL-B nrPDB 209 3e-54 3GLM-A nrPDB 139 3e-33 1PIX-A nrPDB 127 1e-29 2F9Y-B nrPDB 66 4e-11 5KDR-B nrPDB 61 1e-09 1OD4-A nrPDB 59 6e-09 2F9Y-A nrPDB 59 7e-09 5VJ1-D nrPDB 58 1e-08 5KDR-A nrPDB 32 0.69 2E6G-A nrPDB 32 0.82 4RUH-A nrPDB 31 1.3 1XR6-A nrPDB 30 3.1 >2A7S-A nrPDB Length = 548 Score = 1124 bits (2907), Expect = 0.0, Method: Compositional matrix adjust. Identities = 548/548 (100%), Positives = 548/548 (100%) Query: 1 MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTAR 60 MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTAR Sbjct: 1 MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTAR 60 Query: 61 ERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVF 120 ERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVF Sbjct: 61 ERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVF 120 Query: 121 GGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGV 180 GGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGV Sbjct: 121 GGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGV 180 Query: 181 IPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHT 240 IPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHT Sbjct: 181 IPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHT 240 Query: 241 HMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLEL 300 HMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLEL Sbjct: 241 HMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLEL 300 Query: 301 DTLIPDSPNQPYDMHEVITRLLDDEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFA 360 DTLIPDSPNQPYDMHEVITRLLDDEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFA Sbjct: 301 DTLIPDSPNQPYDMHEVITRLLDDEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFA 360 Query: 361 GCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEAT 420 GCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEAT Sbjct: 361 GCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEAT 420 Query: 421 VPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAAN 480 VPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAAN Sbjct: 421 VPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAAN 480 Query: 481 GEDIDKLRLRLQQEYEDTLVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPP 540 GEDIDKLRLRLQQEYEDTLVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPP Sbjct: 481 GEDIDKLRLRLQQEYEDTLVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPP 540 Query: 541 KKHGNVPL 548 KKHGNVPL Sbjct: 541 KKHGNVPL 548 >3IBB-A nrPDB Length = 530 Score = 728 bits (1879), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/535 (68%), Positives = 418/535 (78%), Gaps = 13/535 (2%) Query: 17 EHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELD 76 E DIHTTAGKLA+L +R EE+ H AVEK HAKGKLTARERI LLDE SFVELD Sbjct: 6 EQQPDIHTTAGKLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELD 65 Query: 77 ALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQ 136 A+HRSTNF L RP GDGVVTGYGT+DGR V +FSQD TVFGG+LGEVYG+KIVKV Sbjct: 66 EFARHRSTNFGLDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVM 125 Query: 137 ELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHV 196 + A+KTG P++GIND GARIQEGV SLG Y IFR N ASGVIPQISL++G AGG V Sbjct: 126 DFALKTGCPVVGINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAV 185 Query: 197 YSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQ 256 YSPA+TDF +MVDQTS MFITGPDVIKTVTGE+V EELGGA TH + SG AH+ A E+ Sbjct: 186 YSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEK 245 Query: 257 DAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENL--TDEDLELDTLIPDSPNQPYDM 314 DA +YV++LLSYLP NN ++ P + P E +L TDED ELDT++PDS NQPYDM Sbjct: 246 DAVEYVKQLLSYLPSNNLSEPPAF-------PEEADLAVTDEDAELDTIVPDSANQPYDM 298 Query: 315 HEVITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAAR 373 H VI +LDD EF E Q +A NI+ GFGR++GRPVGIVANQP FAGCLDI ASEKAAR Sbjct: 299 HSVIEHVLDDAEFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAAR 358 Query: 374 FVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYG 433 FVRTCD FN+P++ VDVPGFLPG DQE++GIIRRGAKL++AY EATVP ITVITRKA+G Sbjct: 359 FVRTCDAFNVPVLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFG 418 Query: 434 GAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQ 493 GAY VMGSK +G D+NLAWPTAQIAVMGA GAV ++R+ +A+A G+D + R RL Q Sbjct: 419 GAYAVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIADA---GDDAEATRARLIQ 475 Query: 494 EYEDTLVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548 EYED L+NPY AAERGYVDAVI PS TR +I LR L K LPPKKHGN+PL Sbjct: 476 EYEDALLNPYTAAERGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPL 530 >5INF-A nrPDB Length = 538 Score = 566 bits (1458), Expect = e-161, Method: Compositional matrix adjust. Identities = 289/526 (54%), Positives = 360/526 (68%), Gaps = 10/526 (1%) Query: 24 TTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRS 83 +TA ++A+L R EE++ + A ++ H KGKLTAR RI LLD SFVELD +HR+ Sbjct: 22 STADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRT 81 Query: 84 TNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTG 143 G RP GDGVVTG+GTIDGR VC+FS D T GGS+GE +G K+VK+ + A+ G Sbjct: 82 VE--AGIPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVG 139 Query: 144 RPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTD 203 P+IGIND GARIQEGV+S+ Y+ + N+ +SGVIPQISLIMG AGG VYSPALTD Sbjct: 140 CPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTD 199 Query: 204 FVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVR 263 F +MV S MF+TGP+V+ V GE+VT E+LGG H SG AHY EQDA +V+ Sbjct: 200 FTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQ 259 Query: 264 ELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD 323 LL YLPPNN AP Y G +T+ DL LDT+IPDS Q YDM +VIT +LD Sbjct: 260 TLLGYLPPNNLDPAPVYDHDCAPG-----ITEADLALDTVIPDSEQQVYDMADVITAVLD 314 Query: 324 D-EFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFN 382 D ++LEI +A+NI+ GR++G V +VANQP H AG LDI+ASEKAARF+R CD FN Sbjct: 315 DGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFN 374 Query: 383 IPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSK 442 IP++ +DVPG+LPG QE+ GIIRRG KL YAY E+TVPKITVITRKAYGG Y VMGS+ Sbjct: 375 IPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSR 434 Query: 443 DMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNP 502 +G D +AWPTA+IAVMGA+ AV ++R++L AA E+ ++ L +Y NP Sbjct: 435 QIGADRVMAWPTAEIAVMGANSAVPILHRREL--AAVPPEERAAVKENLVDDYRRRFGNP 492 Query: 503 YVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548 Y AA GYVD VI PS TR + AL L K P +KHGN+PL Sbjct: 493 YEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 538 >3N6R-B nrPDB Length = 531 Score = 561 bits (1445), Expect = e-160, Method: Compositional matrix adjust. Identities = 281/527 (53%), Positives = 361/527 (68%), Gaps = 16/527 (3%) Query: 23 HTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHR 82 H L +L RR + G+ ++ H +GKLTARER+ LLDE SF E D HR Sbjct: 20 HMMKDILEQLEDRRAAARLGGGQKRIDAQHGRGKLTARERVDLLLDEGSFEEFDMFVTHR 79 Query: 83 STNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKT 142 T+FN+ +++P GDGVVTG+GTI+GR V +FSQD TV GGS+ E + +KI K+ ++A++ Sbjct: 80 CTDFNMQDQKPAGDGVVTGWGTINGRVVYVFSQDFTVLGGSVSETHSKKICKIMDMAMQN 139 Query: 143 GRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALT 202 G P+IGIND GARIQEGV SL Y +F+ NI+ASGV+PQIS+IMG AGG VYSPA+T Sbjct: 140 GAPVIGINDSGGARIQEGVDSLAGYGEVFQRNIMASGVVPQISMIMGPCAGGAVYSPAMT 199 Query: 203 DFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYV 262 DF+ MV +S MF+TGPDV+KTVT E+V+ EELGGA TH KS A A + +A V Sbjct: 200 DFIFMVKDSSYMFVTGPDVVKTVTNEQVSAEELGGATTHTRKSSVADAAFENDVEALAEV 259 Query: 263 RELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLL 322 R L+ +LP NN + P P ++ + LDTL+PD+PN PYDM E+I +L Sbjct: 260 RRLVDFLPLNN-------REKPPVRPFFDDPDRIEPSLDTLVPDNPNTPYDMKELIHKLA 312 Query: 323 DD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCF 381 D+ +F EIQ +A+NI+ GF R++GR VG+VANQP AGCLDI++S KAARFVR CD F Sbjct: 313 DEGDFYEIQEEFAKNIITGFIRLEGRTVGVVANQPLVLAGCLDIDSSRKAARFVRFCDAF 372 Query: 382 NIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGS 441 IP++ L+DVPGFLPGT QEY G+I+ GAKLLYAYGEATVP +TVITRKAYGGAY VM S Sbjct: 373 EIPLLTLIDVPGFLPGTSQEYGGVIKHGAKLLYAYGEATVPMVTVITRKAYGGAYVVMSS 432 Query: 442 KDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVN 501 K + D N AWPTA++AVMGA GA ++R L D +K+ + +YE+ N Sbjct: 433 KHLRADFNYAWPTAEVAVMGAKGATEIIHRGDLG-------DPEKI-AQHTADYEERFAN 484 Query: 502 PYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548 P+VA+ERG+VD VI P TR + A L K Q+P KKH N+PL Sbjct: 485 PFVASERGFVDEVIQPRSTRKRVARAFASLRNKSVQMPWKKHDNIPL 531 >1X0U-A nrPDB Length = 522 Score = 527 bits (1357), Expect = e-150, Method: Compositional matrix adjust. Identities = 264/523 (50%), Positives = 354/523 (67%), Gaps = 15/523 (2%) Query: 29 LAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNL 88 + EL + +E++ G++ ++ H+KGKLTARER+ L D+ F E+ A R+T F L Sbjct: 12 IEELRQLKEKAYKGGGDERIQFQHSKGKLTARERLALLFDDGKFNEIMTFATTRATEFGL 71 Query: 89 GEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIG 148 ++R GDGVVTG+G +DGR V ++QD TV GGSLGE + KIV+ ELA+K G P++G Sbjct: 72 DKQRFYGDGVVTGWGKVDGRTVFAYAQDFTVLGGSLGETHANKIVRAYELALKVGAPVVG 131 Query: 149 INDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVIMV 208 IND GARIQEG +SL Y +F+ N++ASGVIPQI+++ G AAGG VYSPALTDF+IM+ Sbjct: 132 INDSGGARIQEGALSLEGYGAVFKMNVMASGVIPQITIMAGPAAGGAVYSPALTDFIIMI 191 Query: 209 D-QTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELLS 267 MF+TGP++ K V GEEV+ ++LGGA H KSG H+ EQ+A + + LLS Sbjct: 192 KGDAYYMFVTGPEITKVVLGEEVSFQDLGGAVVHATKSGVVHFMVDSEQEAINLTKRLLS 251 Query: 268 YLPPNNSTDAPRYQAAAPTGPIEENLTDEDLE-LDTLIPDSPNQPYDMHEVITRLLDD-E 325 YLP NN + P P D D ++ ++P+ +PY+M E+I +++D+ E Sbjct: 252 YLPSNNMEEPPYIDTGDPA--------DRDATGVEQIVPNDAAKPYNMREIIYKIVDNGE 303 Query: 326 FLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPI 385 FLE+ +AQNI+VGF RI G VGIVAN P F G +DI+A++KAARF+R CD FNIP+ Sbjct: 304 FLEVHKHWAQNIIVGFARIAGNVVGIVANNPEEFGGSIDIDAADKAARFIRFCDAFNIPL 363 Query: 386 VMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMG 445 + LVD PG++PGTDQEY GIIR GAK+LYA+ EATVPKITVI RK+YGGA+ M K +G Sbjct: 364 ISLVDTPGYVPGTDQEYKGIIRHGAKMLYAFAEATVPKITVIVRKSYGGAHIAMSIKSLG 423 Query: 446 CDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNPYVA 505 D+ AWPTA+IAV G GAV +YR+++ + A+N +D+ K R+ EY NPY A Sbjct: 424 ADLVYAWPTAEIAVTGPEGAVRILYRKEI-QQASNPDDVLKQRI---AEYRKLFANPYWA 479 Query: 506 AERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548 AE+G VD VI P TR I L +L+ K PKKHGN+PL Sbjct: 480 AEKGLVDDVIEPKDTRRVIVAGLEMLKTKREYRYPKKHGNIPL 522 >1ON3-A nrPDB Length = 523 Score = 502 bits (1293), Expect = e-142, Method: Compositional matrix adjust. Identities = 266/525 (50%), Positives = 344/525 (65%), Gaps = 14/525 (2%) Query: 24 TTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRS 83 T G++ +L ++R+ GE VEK H++GK TARER+ LLD SF E+ A KHR+ Sbjct: 11 TMEGRVEQLAEQRQVIEAGGGERRVEKQHSQGKQTARERLNNLLDPHSFDEVGAFRKHRT 70 Query: 84 TNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTG 143 T F + + DGVVTG GTI GR V SQD TV GGS GE K+V+ E A+ TG Sbjct: 71 TLFGMDKAVVPADGVVTGRGTILGRPVHAASQDFTVMGGSAGETQSTKVVETMEQALLTG 130 Query: 144 RPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTD 203 P + D GARIQEG+ SL Y ++F N+ SGV+PQI++I G AGG YSPALTD Sbjct: 131 TPFLFFYDSGGARIQEGIDSLSGYGKMFFANVKLSGVVPQIAIIAGPCAGGASYSPALTD 190 Query: 204 FVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVR 263 F+IM + + MFITGP VIK+VTGE+VT +ELGGA HMA SG H+ A + A + Sbjct: 191 FIIMT-KKAHMFITGPQVIKSVTGEDVTADELGGAEAHMAISGNIHFVAEDDDAAELIAK 249 Query: 264 ELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD 323 +LLS+LP NN+ +A P + N EL ++P + YD+ +VI +++D Sbjct: 250 KLLSFLPQNNTEEASFVN---PNNDVSPNT-----ELRDIVPIDGKKGYDVRDVIAKIVD 301 Query: 324 -DEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFN 382 ++LE++AGYA N+V F R++GR VGIVANQP+ +GCLDINAS+KAA FV CD FN Sbjct: 302 WGDYLEVKAGYATNLVTAFARVNGRSVGIVANQPSVMSGCLDINASDKAAEFVNFCDSFN 361 Query: 383 IPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSK 442 IP+V LVDVPGFLPG QEY GIIR GAK+LYAY EATVPKITV+ RKAYGG+Y M ++ Sbjct: 362 IPLVQLVDVPGFLPGVQQEYGGIIRHGAKMLYAYSEATVPKITVVLRKAYGGSYLAMCNR 421 Query: 443 DMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNP 502 D+G D AWP+A+IAVMGA GA ++R+++ A +D D +R +EY++ P Sbjct: 422 DLGADAVYAWPSAEIAVMGAEGAANVIFRKEIKAA----DDPDAMRAEKIEEYQNAFNTP 477 Query: 503 YVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVP 547 YVAA RG VD VI P+ TR I +AL + K P KKHGN P Sbjct: 478 YVAAARGQVDDVIDPADTRRKIASALEMYATKRQTRPAKKHGNFP 522 >4L6W-A nrPDB Length = 493 Score = 347 bits (891), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 197/456 (43%), Positives = 277/456 (60%), Gaps = 27/456 (5%) Query: 97 GVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGAR 156 GV+ GT++G F D TV GG++G IV + AI+ P++GI GAR Sbjct: 61 GVLAAAGTVNGVRTIAFCTDGTVMGGAMGVEGCTHIVNAYDTAIEDQSPIVGIWHSGGAR 120 Query: 157 IQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFI 216 + EGV +L ++F I ASG IPQIS+++G AAGG Y PALTD V+M + S++F+ Sbjct: 121 LAEGVRALHAVGQVFEAMIRASGYIPQISVVVGFAAGGAAYGPALTDVVVMAPE-SRVFV 179 Query: 217 TGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTD 276 TGPDV+++VTGE+V M LGG TH KSG H A E DA+D R L+ D Sbjct: 180 TGPDVVRSVTGEDVDMASLGGPETHHKKSGVCHIVADDELDAYDRGRRLVGLFCQQGHFD 239 Query: 277 APRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLDDE--FLEIQAGYA 334 + +A D ++ L+P+S + YD+ ++T +LD + F E QA +A Sbjct: 240 RSKAEAG-------------DTDIHALLPESSRRAYDVRPIVTAILDADTPFDEFQANWA 286 Query: 335 QNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGF 394 ++VVG GR+ GR VG++AN P GCL+ ++EKAARFVR CD F IP+V++VDVPG+ Sbjct: 287 PSMVVGLGRLSGRTVGVLANNPLRLGGCLNSESAEKAARFVRLCDAFGIPLVVVVDVPGY 346 Query: 395 LPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPT 454 LPG DQE+ G++RRGAKLL+A+GE TVP++T++TRK YGGAY M S+ + AWP Sbjct: 347 LPGVDQEWGGVVRRGAKLLHAFGECTVPRVTLVTRKTYGGAYIAMNSRSLNATKVFAWPD 406 Query: 455 AQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNPYVAAERGYVDAV 514 A++AVMGA AVG +++++L AAA + + L +L E+E A + G VD Sbjct: 407 AEVAVMGAKAAVGILHKKKL--AAAPEHEREALHDQLAAEHERIAGGVDSALDIGVVDEK 464 Query: 515 IPPSHTRGYIGTALRLLERKIAQLPPK--KHGNVPL 548 I P+HTR + AL AQ P + +H N+PL Sbjct: 465 IDPAHTRSKLTEAL-------AQAPARRGRHKNIPL 493 >4Q0G-A nrPDB Length = 529 Score = 255 bits (651), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 171/513 (33%), Positives = 265/513 (51%), Gaps = 30/513 (5%) Query: 29 LAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDS-FVELDALAKHRSTNFN 87 +AEL+ + + E A ++ ++GKL RER+ LLD S F+EL LA Sbjct: 20 VAELNNKLAAAALGGNERARKRHVSRGKLLPRERVDRLLDPGSPFLELAPLA----AGGM 75 Query: 88 LGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLI 147 G++ P G G++TG G + GR I + DATV GG+ + +K ++ QE+A++ P I Sbjct: 76 YGDESP-GAGIITGIGRVSGRQCVIVANDATVKGGTYYPMTVKKHLRAQEVALQNMLPCI 134 Query: 148 GINDGAGA---RIQEGVVSLGLYSRIFRNN-ILASGVIPQISLIMGAAAGGHVYSPALTD 203 + D GA R E + RIF N +++ IPQ++ ++G+ G Y PA++D Sbjct: 135 YLVDSGGAFLPRQDEVFPDREHFGRIFYNQATMSAKGIPQVAAVLGSCTAGGAYVPAMSD 194 Query: 204 FVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVR 263 ++V + +F+ GP ++K TGE V+ EELGG H SG + A ++DA VR Sbjct: 195 EAVIVREQGTIFLGGPPLVKAATGEIVSAEELGGGDLHSRTSGVTDHLADDDEDALRIVR 254 Query: 264 ELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD 323 + P ++ P P EL ++P P PYD+HEV+ R++D Sbjct: 255 AIADTFGPCEPAQWDVRRSVEPKYP--------QAELYDVVPPDPRVPYDVHEVVVRIVD 306 Query: 324 -DEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFN 382 EF E +A Y + +V F R+ G PVGIVAN G L ++ K A F+ CD Sbjct: 307 GSEFSEFKAKYGKTLVTAFARVHGHPVGIVANN-----GVLFSESALKGAHFIELCDKRK 361 Query: 383 IPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSK 442 IP++ L ++ GF+ G D E GI + GAK++ A A VPK+TV+ +YG M + Sbjct: 362 IPLLFLQNIAGFMVGRDYEAGGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGR 421 Query: 443 DMGCDVNLAWPTAQIAVMG---ASGAVGFVYRQQLAEAAA--NGEDIDKLRLRLQQEYED 497 WP A+I+VMG A+ + V +QL+ A + ++ + + ++ +YED Sbjct: 422 AYSPRFLWMWPNARISVMGGEQAASVLATVRGEQLSAAGTPWSPDEEEAFKAPIRAQYED 481 Query: 498 TLVNPYVAAERGYVDAVIPPSHTRGYIGTALRL 530 NPY + R + D +I P+ TR +G AL L Sbjct: 482 Q-GNPYYSTARLWDDGIIDPADTRTVVGLALSL 513 >3U9S-B nrPDB Length = 555 Score = 237 bits (604), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 169/495 (34%), Positives = 249/495 (50%), Gaps = 33/495 (6%) Query: 40 LHPVGEDAVEKVH-AKGKLTARERIYALLDEDS-FVELDALAKHRSTNFNLGEKRPLGDG 97 +H G A + H A+GKL RERI LLD S F+EL ALA H + G Sbjct: 56 IHEGGGSAAQARHSARGKLLVRERINRLLDPGSPFLELSALAAHEVYGEEVAAA-----G 110 Query: 98 VVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGA-- 155 +V G G ++G + I DATV GG+ + +K ++ Q +A++ P I + D GA Sbjct: 111 IVAGIGRVEGVECMIVGNDATVKGGTYYPLTVKKHLRAQAIALENRLPCIYLVDSGGANL 170 Query: 156 -RIQEGVVSLGLYSRIFRN--NILASGVIPQISLIMGAAAGGHVYSPALTDFVIMVDQTS 212 R E + RIF N N+ A G IPQI+++MG+ G Y PA++D +MV + + Sbjct: 171 PRQDEVFPDREHFGRIFFNQANMSARG-IPQIAVVMGSCTAGGAYVPAMSDETVMVREQA 229 Query: 213 QMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELLSYLPPN 272 +F+ GP ++K TGE V+ EELGGA H SG A + A + A R ++ L Sbjct: 230 TIFLAGPPLVKAATGEVVSAEELGGADVHCKVSGVADHYAEDDDHALAIARRCVANL--- 286 Query: 273 NSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD-DEFLEIQA 331 N + Q AP P+ EL +IP QPYD+ EVI RL+D EF E +A Sbjct: 287 NWRKQGQLQCRAPRAPLYPA-----EELYGVIPADSKQPYDVREVIARLVDGSEFDEFKA 341 Query: 332 GYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDV 391 + +V GF + G P+ I+AN FA A++K A F+ IP++ L ++ Sbjct: 342 LFGTTLVCGFAHLHGYPIAILANNGILFA-----EAAQKGAHFIELACQRGIPLLFLQNI 396 Query: 392 PGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVNLA 451 GF+ G E GI + GAKL+ A A VPK TV+ ++G M + Sbjct: 397 TGFMVGQKYEAGGIAKHGAKLVTAVACARVPKFTVLIGGSFGAGNYGMCGRAYDPRFLWM 456 Query: 452 WPTAQIAVMGASGAVGFVYRQQLAEAAANGEDID-----KLRLRLQQEYEDTLVNPYVAA 506 WP A+I VMG A G + + + +A G+ + K++ + ++YE +PY ++ Sbjct: 457 WPNARIGVMGGEQAAGVLAQVKREQAERAGQQLGVEEEAKIKAPILEQYEHQ-GHPYYSS 515 Query: 507 ERGYVDAVIPPSHTR 521 R + D VI P+ TR Sbjct: 516 ARLWDDGVIDPAQTR 530 >5IKL-B nrPDB Length = 537 Score = 209 bits (531), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 143/493 (29%), Positives = 246/493 (49%), Gaps = 27/493 (5%) Query: 46 DAVEKVHAKGKLTARERIYALLDEDS-FVELDALAKHRSTNFNLGEKRPLGDGVVTGYGT 104 +A K +G+L RER+ LLD + F+EL +LA ++ + G + G + Sbjct: 41 EARPKFEKRGQLLPRERLALLLDPGAPFLELSSLAGYKLHDDKDGTQA---GGGIIAGIG 97 Query: 105 IDGRDVCIFS-QDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVS 163 C+ S ++ + GG++ +K +++Q++A++ P++ + + GA + Sbjct: 98 YIAGVRCLVSASNSAIKGGTISPTGLKKTLRLQQIAMENKLPVVTLTESGGANLNYAAEI 157 Query: 164 LGLYSRIFRNNILASGV-IPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVI 222 +R F N S + IPQ++++ G++ G Y P L+D+V++V ++MF+ GP ++ Sbjct: 158 FVEGARGFANQARISAMGIPQVTVVHGSSTAGGAYQPGLSDYVVVVRGKAKMFLAGPPLL 217 Query: 223 KTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDA-PRYQ 281 K TGE + EELGGA H +GTA Y A + D RE++ LP N A P Sbjct: 218 KAATGEIASDEELGGAELHAQVAGTAEYLAENDADGVRLAREIVGMLPWNAQLPARPARS 277 Query: 282 AAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD-DEFLEIQAGYAQNIVVG 340 P P+EE L ++P P +PYD+ E++ R+ D EFL+ + + V G Sbjct: 278 WREPLYPVEELL--------GVVPADPKKPYDVREIVARIADGSEFLDFKNEFDGQTVCG 329 Query: 341 FGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQ 400 RI+G G++ N G + + KAA+F++ C+ N P++ L + GF+ GT+ Sbjct: 330 HLRIEGHACGLIGNN-----GPITPQGAAKAAQFIQLCEQSNTPLLFLHNTTGFMVGTES 384 Query: 401 EYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVM 460 E G+I+ G+K++ A A VPK+T++ +YG M + + AWP ++ AVM Sbjct: 385 ERQGVIKHGSKMIQAVANARVPKLTLVVGGSYGAGNYAMCGRGLDPRFIFAWPNSRTAVM 444 Query: 461 GASGAVGFVYRQQLAEA-AANGEDIDKLRLRLQQEYEDTLVNPYVAAERG----YVDAVI 515 G + A G V R E A G++ D L + + ++ A G + D ++ Sbjct: 445 GGAQA-GKVLRIVTEEKHAKEGKEADPKMLEMLETVTAQKLDSQSTALYGTASLWDDGLV 503 Query: 516 PPSHTRGYIGTAL 528 P +R +G L Sbjct: 504 DPRDSRRLLGYLL 516 >3GLM-A nrPDB Length = 588 Score = 139 bits (351), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 137/545 (25%), Positives = 237/545 (43%), Gaps = 76/545 (13%) Query: 30 AELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNLG 89 +++H+ +++L G + EK++ +G+L+A +RI AL+D ++ L++L + F Sbjct: 36 SDIHESIKKALD-AGITSEEKLNERGQLSAMQRINALIDPGTWCPLNSLFNPENNKFGT- 93 Query: 90 EKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGI 149 +V G G +DG+ V I + D G+ E +++ + A PLI + Sbjct: 94 ------TNIVNGLGRVDGKWVYIVASDNKKMAGAWVPGQAENLIRCSDAAKMMHLPLIYL 147 Query: 150 NDGAGARI--QEGVVS--LGLYSRIFRNNILASGVIPQISLIMG---AAAGGHVYSPALT 202 + +G Q+ V G + FRN+ L IP I I G A G H SP Sbjct: 148 LNCSGVEFPNQDKVYPNRRGGGTPFFRNSELNQLGIPVIVGIYGTNPAGGGYHSISPT-- 205 Query: 203 DFVIMVDQTSQMFITGPDVIKTVT---------GEEVTMEELGGAHTHMAKSGTA--HYA 251 +++ Q + M + G ++ + E++ ++ + + G+ HY Sbjct: 206 --ILIAHQDANMAVGGAGILSGMNPKGYIDDEAAEQIIAAQIENSKLKVPAPGSVPIHYD 263 Query: 252 ASG--------EQDAFDYVRELLSYLPPNN----STDAPRYQAAAPTGPIEENLTDEDLE 299 +G + D +++ +SYLP N D P+ AP P E+ Sbjct: 264 ETGFFREVYQNDLGVIDGIKKYISYLPAYNLEFFRVDTPK----APQLPAED-------- 311 Query: 300 LDTLIPDSPNQPYDMHEVITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVAN---- 354 L ++IP + +PYD++EVI RL D+ EF E + GY +V G +++G VG++AN Sbjct: 312 LYSIIPMNQKRPYDIYEVIARLFDNSEFSEYKKGYGPEMVTGLAKVNGLLVGVIANVQGL 371 Query: 355 ---------QPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGI 405 G L K FV C IP++ L D G G + E + Sbjct: 372 LMNYPEYKQNSVGIGGKLYRQGLIKMNEFVTLCARDRIPLIWLQDTTGIDVGDEAEKAEL 431 Query: 406 IRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVN---LAWPTAQIAVMGA 462 + G L+Y+ + +P + + RKA A+ V+G G + N + + VM Sbjct: 432 LGLGQSLIYSIENSKLPSLEITIRKASAAAHYVLGGPQ-GNNTNVFSIGTGACEYYVMPG 490 Query: 463 SGAVGFVYRQQLAEAAANGEDIDKLRLRLQ---QEYEDTLVNPYVAAERGYVDAVIPPSH 519 A +Y ++L +A GED+ + ++ Q Y D P E+G VD ++ + Sbjct: 491 ETAANAMYSRKLVKAKKAGEDLQPIIGKMNDMIQMYTDK-SRPKYCTEKGMVDEIVDMTE 549 Query: 520 TRGYI 524 R YI Sbjct: 550 VRPYI 554 >1PIX-A nrPDB Length = 587 Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 144/550 (26%), Positives = 229/550 (41%), Gaps = 82/550 (14%) Query: 31 ELHKRREESLHPVGEDAVE------KVHAKGKLTARERIYALLDEDSFVELDALAKHRST 84 E K+ EE +H + ++A E V+ +G+LTA +RI L++ S+ L+ L Sbjct: 29 EQLKKIEEEIHQLIKEAQEAGKADADVNKRGELTALQRIEKLVEPGSWRPLNTL------ 82 Query: 85 NFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGR 144 FN + +V G G ++G+ + + D G+ E +++ + A Sbjct: 83 -FNPQGNKNGSVAIVKGLGRVNGKWCVVVASDNKKLAGAWVPGQAECLLRASDTAKTLHV 141 Query: 145 PLIGINDGAGARI--QEGVV--SLGLYSRIFRNNILASGVIPQISLIMG---AAAGGHVY 197 PL+ + + +G + QE V G + FRN L IP I I G A G H Sbjct: 142 PLVYVLNCSGVKFDEQEKVYPNRRGGGTPFFRNAELNQLGIPVIVGIYGTNPAGGGYHSI 201 Query: 198 SPALTDFVIMVDQTSQMFITGPDV-----------------IKTVTGEEVTMEELGGAHT 240 SP VI+ + + M + G + I + E G Sbjct: 202 SPT----VIIAHEKANMAVGGAGIMGGMNPKGHVDLEYANEIADMVDRTGKTEPPGAVDI 257 Query: 241 HMAKSGTAHYAASGEQDAFD----YVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDE 296 H ++G + E+ + YV L Y P D P+ AP P ++ Sbjct: 258 HYTETGFMREVYASEEGVLEGIKKYVGMLPKYDPEFFRVDDPK----APAFPADD----- 308 Query: 297 DLELDTLIPDSPNQPYDMHEVITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVAN- 354 L +++P + + YD++ VI RL D+ E E + GY +V G +++G VG+VAN Sbjct: 309 ---LYSMVPLNDKRAYDIYNVIARLFDNSELHEYKKGYGPEMVTGLAKVNGLLVGVVANV 365 Query: 355 ------QPTHFA-------GCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQE 401 P + A G L K FV C +PIV + D G G D E Sbjct: 366 QGLLMNYPEYKAAGSVGIGGKLYRQGLVKMNEFVTLCARDRLPIVWIQDTTGIDVGNDAE 425 Query: 402 YNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVN---LAWPTAQIA 458 ++ G L+Y+ + +P+ + RK A+ V+G G D N + +IA Sbjct: 426 KAELLGLGQSLIYSIQTSHIPQFEITLRKGTAAAHYVLGGPQ-GNDTNAFSIGTAATEIA 484 Query: 459 VMGASGAVGFVYRQQLAEAAANGED----IDKLRLRLQQEYEDTLVNPYVAAERGYVDAV 514 VM A +Y ++LA+ G+D IDK+ +Q Y T P V AE G VD + Sbjct: 485 VMNGETAATAMYSRRLAKDRKAGKDLQPTIDKMNNLIQAFY--TKSRPKVCAELGLVDEI 542 Query: 515 IPPSHTRGYI 524 + + RGY+ Sbjct: 543 VDMNKIRGYV 552 >2F9Y-B nrPDB Length = 304 Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 57/194 (29%), Positives = 91/194 (46%), Gaps = 25/194 (12%) Query: 56 KLTARERIYALLDEDSFVEL-------DALAKHRSTNFN---------LGEKRPLGDGVV 99 ++TAR R+++LLDE S VEL D L S + GEK D +V Sbjct: 54 RMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEK----DALV 109 Query: 100 TGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQE 159 GT+ G V + + GGS+G V G + V+ E A++ PLI + GAR+QE Sbjct: 110 VMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQE 169 Query: 160 GVVSLGLYSRIFRNNILASGV---IPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFI 216 ++SL ++ + LA +P IS++ GG S A+ + + + + + Sbjct: 170 ALMSLMQMAKT--SAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGF 227 Query: 217 TGPDVIKTVTGEEV 230 GP VI+ E++ Sbjct: 228 AGPRVIEQTVREKL 241 >5KDR-B nrPDB Length = 285 Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 9/117 (7%) Query: 57 LTARERIYALLDEDSFVELD-ALAKHRSTNF--------NLGEKRPLGDGVVTGYGTIDG 107 LTA +RI A+ DE SF E D + +F +K L + VVTG +DG Sbjct: 61 LTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDG 120 Query: 108 RDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSL 164 + D+ GS+G V GEKI ++ + + P I + GAR+QEG++SL Sbjct: 121 MKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISL 177 >1OD4-A nrPDB Length = 805 Score = 58.9 bits (141), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 97/402 (24%), Positives = 163/402 (40%), Gaps = 75/402 (18%) Query: 136 QELAIKTGRPLIGINDGAGARIQEGV-VSLGLYSRIFRNNILASGVIPQISLIMGAAAGG 194 + IKT +IG DG G G + G SR + + I I+L+ + G Sbjct: 258 ERFVIKT---IIGSEDGLGVECLRGSGLIAGATSRAYHD-------IFTITLVTCRSVGI 307 Query: 195 HVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTME--ELGGAHTHMAKSGTAHYAA 252 Y L I V + + +TG I + G EV +LGG M +G +H A Sbjct: 308 GAYLVRLGQRAIQV-EGQPIILTGAPAINKMLGREVYTSNLQLGGTQI-MYNNGVSHLTA 365 Query: 253 SGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPY 312 + + + E +SY+P + P I E D +D P + ++ Y Sbjct: 366 VDDLAGVEKIVEWMSYVPAKRNMPVP----------ILETKDTWDRPVD-FTPTN-DETY 413 Query: 313 DMHEVITR----------LLDD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAG 361 D+ +I L D F E +G+A+ +VVG R+ G P+G++ + Sbjct: 414 DVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVEN 473 Query: 362 CL-----DINASE-------------KAARFVRTCDCFN----IPIVMLVDVPGFLPGTD 399 + + N++E A + + + FN +P+++L + GF G Sbjct: 474 LIPADPANPNSAETLIQEPGQVWHPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQR 533 Query: 400 QEYNGIIRRGAKLLYAYGEATVPKITVI--TRKAYGGAYCVM------GSKDMGCDVNLA 451 +N +++ G+ ++ A + P I I T + GG++ V+ +M DVN Sbjct: 534 DMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVN-- 591 Query: 452 WPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLR-LRLQ 492 A+ V+ G VG +R++ N D DK R LR Q Sbjct: 592 ---ARAGVLEPQGMVGIKFRREKLLDTMNRLD-DKYRELRSQ 629 >2F9Y-A nrPDB Length = 339 Score = 58.5 bits (140), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 61/215 (28%), Positives = 90/215 (41%), Gaps = 21/215 (9%) Query: 308 PNQPYDMHEVITRLLDDEFLEIQA--GYAQN--IVVGFGRIDGRPVGIVANQPTHFA--- 360 P +PY + V RL DEF E+ YA + IV G R+DGRPV I+ +Q Sbjct: 90 PQRPYTLDYV--RLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEK 147 Query: 361 -----GCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYA 415 G KA R ++ + F +PI+ +D PG PG E G A+ L Sbjct: 148 IRRNFGMPAPEGYRKALRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLRE 207 Query: 416 YGEATVPKI-TVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQ-Q 473 VP + TVI GGA + +G VN+ + +V+ G +++ Sbjct: 208 MSRLGVPVVCTVIGEGGSGGALAI----GVGDKVNM-LQYSTYSVISPEGCASILWKSAD 262 Query: 474 LAEAAANGEDIDKLRLRLQQEYEDTLVNPYVAAER 508 A AA I + RL+ + + + P A R Sbjct: 263 KAPLAAEAMGIIRPRLKELKLIDSIIPEPLGGAHR 297 >5VJ1-D nrPDB Length = 287 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 58/182 (31%), Positives = 85/182 (46%), Gaps = 12/182 (6%) Query: 56 KLTARERIYALLDEDSFVEL-DALAKHRSTNFNLGEKRPLGD-GVVTGYGTIDGRDVCIF 113 +L AR+R ALLD SF EL D A +S P D GVV G +DG+ + Sbjct: 15 ELGARQRARALLDAGSFRELLDPFAGVQSPWLERQGIVPQADDGVVVARGLLDGQPAVLA 74 Query: 114 SQDATVFGGSLGEVYGEKIVKVQELAIKTG------RPLIGINDGAGARIQEGVVSLGLY 167 + + GGSLGEV G KI ELA + R L+ + G G R+QE + L Sbjct: 75 AIEGAFQGGSLGEVSGAKIAGALELAAEDNRNGVPTRALLLLETG-GVRLQEANLGLAAI 133 Query: 168 SRIFRNNILASGVIPQISLIMGAAA--GGHVYSPALTDFVIMVDQTSQMFITGPDVIKTV 225 + I + P +++I G GG + L +V +V + +++ + GP VI+ Sbjct: 134 AEIQAAIVDLQRYQPVVAVIAGPVGCFGGMSIAAGLCSYV-LVTREARLGLNGPQVIEQE 192 Query: 226 TG 227 G Sbjct: 193 AG 194 >5KDR-A nrPDB Length = 327 Score = 32.0 bits (71), Expect = 0.69, Method: Compositional matrix adjust. Identities = 58/249 (23%), Positives = 94/249 (37%), Gaps = 61/249 (24%) Query: 70 DSFVELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDA---------TVF 120 DSF+EL H NF P ++ G G ++GR V + Q F Sbjct: 90 DSFMEL-----HGDRNFR---DDP---AMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNF 138 Query: 121 GGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNI-LASG 179 G + E Y K +++ + A K RP+ D GA + G I N I +AS Sbjct: 139 GMAHPEGY-RKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASL 197 Query: 180 VIPQISLIMGAAAGGHVYSPALTDFVIMVDQTS-------------------------QM 214 +P I++++G G + + V+M++ ++ M Sbjct: 198 KVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETM 257 Query: 215 FITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQ--------------DAFD 260 IT D+ + ++V E LGGAH + + A +A Q D F+ Sbjct: 258 KITAHDIKQLGIIDDVISEPLGGAHKDIEQQALAIKSAFVAQLDSLESLSRDEIANDRFE 317 Query: 261 YVRELLSYL 269 R + SY+ Sbjct: 318 KFRNIGSYI 326 >2E6G-A nrPDB Length = 244 Score = 31.6 bits (70), Expect = 0.82, Method: Compositional matrix adjust. Identities = 14/57 (24%), Positives = 25/57 (43%) Query: 196 VYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAA 252 +YSP L Q ++F+ PD ++ G +T+ A+ H + H+ A Sbjct: 11 IYSPGLWALAEAASQFGEVFVAAPDTEQSAAGHAITIAHPVRAYPHPSPLHAPHFPA 67 >4RUH-A nrPDB Length = 475 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 23/108 (21%) Query: 67 LDEDSFVELDALAKHR-----STNFNLGEKRPLGDGVVTGYGTIDGRDVCIF-------S 114 LDE F D K S N+ LG+K+P YG R +C F + Sbjct: 173 LDELIFARKDTFFKDVDYVCISDNYWLGKKKP-----CITYGL---RGICYFFIEVECSN 224 Query: 115 QD--ATVFGGSLGEVYGEKIVKVQELAIKTGRPLI-GINDGAGARIQE 159 +D + V+GGS+ E + I+ + L K G LI GIN+ A +E Sbjct: 225 KDLHSGVYGGSVHEAMTDLILLMGSLVDKRGNILIPGINEAVAAVTEE 272 >1XR6-A nrPDB Length = 460 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 51/120 (42%), Gaps = 21/120 (17%) Query: 35 RREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAK---HRSTNFNLGEK 91 R +E+L G D K +L +E+I A + +E ++ R+T NL K Sbjct: 140 RLKEALDKYGVDLPMITFLKDELRKKEKISA--GKTRVIEASSINDTILFRTTFGNLFSK 197 Query: 92 RPLGDGVVTGYGT--------------IDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQE 137 L GVVTG +DG CI + D T + GS+ V+ + + KV E Sbjct: 198 FHLNPGVVTGSAVGCDPETFWSKIPVMLDGD--CIMAFDYTNYDGSIHPVWFQALKKVLE 255 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2A7S-A nrPDB 788 0.0 3IBB-A nrPDB 710 0.0 3N6R-B nrPDB 674 0.0 5INF-A nrPDB 647 0.0 1ON3-A nrPDB 644 0.0 1X0U-A nrPDB 640 0.0 4Q0G-A nrPDB 547 e-156 3U9S-B nrPDB 532 e-151 5IKL-B nrPDB 492 e-139 3GLM-A nrPDB 465 e-131 4L6W-A nrPDB 465 e-131 1PIX-A nrPDB 446 e-125 1OD4-A nrPDB 267 1e-71 2F9Y-A nrPDB 173 2e-43 2F9Y-B nrPDB 168 4e-42 5KDR-B nrPDB 153 3e-37 5VJ1-D nrPDB 146 2e-35 Sequences not found previously or not previously below threshold: 5KDR-A nrPDB 110 2e-24 5VIP-A nrPDB 40 0.002 1O9J-A nrPDB 37 0.030 2PG0-A nrPDB 33 0.30 5Y6T-A nrPDB 32 0.81 2E7J-A nrPDB 32 0.88 4PY5-A nrPDB 32 0.88 2ZYA-A nrPDB 32 0.91 4DYD-A nrPDB 31 1.0 4HST-B nrPDB 31 1.1 4JCS-A nrPDB 31 1.1 5NNZ-B nrPDB 31 1.2 4JWV-A nrPDB 31 1.2 5W8P-A nrPDB 31 1.8 4K1W-A nrPDB 31 2.1 4Q1V-A nrPDB 30 2.7 4HJH-A nrPDB 30 2.7 4IS3-A nrPDB 30 3.1 2YRI-A nrPDB 30 3.4 5H9U-C nrPDB 29 4.0 4IZC-A nrPDB 29 6.0 5T12-A nrPDB 29 8.2 >2A7S-A nrPDB Length = 548 Score = 788 bits (2036), Expect = 0.0, Method: Composition-based stats. Identities = 548/548 (100%), Positives = 548/548 (100%) Query: 1 MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTAR 60 MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTAR Sbjct: 1 MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTAR 60 Query: 61 ERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVF 120 ERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVF Sbjct: 61 ERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVF 120 Query: 121 GGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGV 180 GGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGV Sbjct: 121 GGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGV 180 Query: 181 IPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHT 240 IPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHT Sbjct: 181 IPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHT 240 Query: 241 HMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLEL 300 HMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLEL Sbjct: 241 HMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLEL 300 Query: 301 DTLIPDSPNQPYDMHEVITRLLDDEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFA 360 DTLIPDSPNQPYDMHEVITRLLDDEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFA Sbjct: 301 DTLIPDSPNQPYDMHEVITRLLDDEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFA 360 Query: 361 GCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEAT 420 GCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEAT Sbjct: 361 GCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEAT 420 Query: 421 VPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAAN 480 VPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAAN Sbjct: 421 VPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAAN 480 Query: 481 GEDIDKLRLRLQQEYEDTLVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPP 540 GEDIDKLRLRLQQEYEDTLVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPP Sbjct: 481 GEDIDKLRLRLQQEYEDTLVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPP 540 Query: 541 KKHGNVPL 548 KKHGNVPL Sbjct: 541 KKHGNVPL 548 >3IBB-A nrPDB Length = 530 Score = 710 bits (1833), Expect = 0.0, Method: Composition-based stats. Identities = 362/533 (67%), Positives = 417/533 (78%), Gaps = 9/533 (1%) Query: 17 EHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELD 76 E DIHTTAGKLA+L +R EE+ H AVEK HAKGKLTARERI LLDE SFVELD Sbjct: 6 EQQPDIHTTAGKLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELD 65 Query: 77 ALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQ 136 A+HRSTNF L RP GDGVVTGYGT+DGR V +FSQD TVFGG+LGEVYG+KIVKV Sbjct: 66 EFARHRSTNFGLDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVM 125 Query: 137 ELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHV 196 + A+KTG P++GIND GARIQEGV SLG Y IFR N ASGVIPQISL++G AGG V Sbjct: 126 DFALKTGCPVVGINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAV 185 Query: 197 YSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQ 256 YSPA+TDF +MVDQTS MFITGPDVIKTVTGE+V EELGGA TH + SG AH+ A E+ Sbjct: 186 YSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEK 245 Query: 257 DAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHE 316 DA +YV++LLSYLP NN ++ P + A + +TDED ELDT++PDS NQPYDMH Sbjct: 246 DAVEYVKQLLSYLPSNNLSEPPAFPEEA-----DLAVTDEDAELDTIVPDSANQPYDMHS 300 Query: 317 VITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFV 375 VI +LDD EF E Q +A NI+ GFGR++GRPVGIVANQP FAGCLDI ASEKAARFV Sbjct: 301 VIEHVLDDAEFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFV 360 Query: 376 RTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGA 435 RTCD FN+P++ VDVPGFLPG DQE++GIIRRGAKL++AY EATVP ITVITRKA+GGA Sbjct: 361 RTCDAFNVPVLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGA 420 Query: 436 YCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEY 495 Y VMGSK +G D+NLAWPTAQIAVMGA GAV ++R+ +A+A G+D + R RL QEY Sbjct: 421 YAVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIADA---GDDAEATRARLIQEY 477 Query: 496 EDTLVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548 ED L+NPY AAERGYVDAVI PS TR +I LR L K LPPKKHGN+PL Sbjct: 478 EDALLNPYTAAERGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPL 530 >3N6R-B nrPDB Length = 531 Score = 674 bits (1739), Expect = 0.0, Method: Composition-based stats. Identities = 281/527 (53%), Positives = 360/527 (68%), Gaps = 16/527 (3%) Query: 23 HTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHR 82 H L +L RR + G+ ++ H +GKLTARER+ LLDE SF E D HR Sbjct: 20 HMMKDILEQLEDRRAAARLGGGQKRIDAQHGRGKLTARERVDLLLDEGSFEEFDMFVTHR 79 Query: 83 STNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKT 142 T+FN+ +++P GDGVVTG+GTI+GR V +FSQD TV GGS+ E + +KI K+ ++A++ Sbjct: 80 CTDFNMQDQKPAGDGVVTGWGTINGRVVYVFSQDFTVLGGSVSETHSKKICKIMDMAMQN 139 Query: 143 GRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALT 202 G P+IGIND GARIQEGV SL Y +F+ NI+ASGV+PQIS+IMG AGG VYSPA+T Sbjct: 140 GAPVIGINDSGGARIQEGVDSLAGYGEVFQRNIMASGVVPQISMIMGPCAGGAVYSPAMT 199 Query: 203 DFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYV 262 DF+ MV +S MF+TGPDV+KTVT E+V+ EELGGA TH KS A A + +A V Sbjct: 200 DFIFMVKDSSYMFVTGPDVVKTVTNEQVSAEELGGATTHTRKSSVADAAFENDVEALAEV 259 Query: 263 RELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLL 322 R L+ +LP NN P P ++ + LDTL+PD+PN PYDM E+I +L Sbjct: 260 RRLVDFLPLNNREKPPVR-------PFFDDPDRIEPSLDTLVPDNPNTPYDMKELIHKLA 312 Query: 323 DD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCF 381 D+ +F EIQ +A+NI+ GF R++GR VG+VANQP AGCLDI++S KAARFVR CD F Sbjct: 313 DEGDFYEIQEEFAKNIITGFIRLEGRTVGVVANQPLVLAGCLDIDSSRKAARFVRFCDAF 372 Query: 382 NIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGS 441 IP++ L+DVPGFLPGT QEY G+I+ GAKLLYAYGEATVP +TVITRKAYGGAY VM S Sbjct: 373 EIPLLTLIDVPGFLPGTSQEYGGVIKHGAKLLYAYGEATVPMVTVITRKAYGGAYVVMSS 432 Query: 442 KDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVN 501 K + D N AWPTA++AVMGA GA ++R L D +K+ + +YE+ N Sbjct: 433 KHLRADFNYAWPTAEVAVMGAKGATEIIHRGDLG-------DPEKI-AQHTADYEERFAN 484 Query: 502 PYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548 P+VA+ERG+VD VI P TR + A L K Q+P KKH N+PL Sbjct: 485 PFVASERGFVDEVIQPRSTRKRVARAFASLRNKSVQMPWKKHDNIPL 531 >5INF-A nrPDB Length = 538 Score = 647 bits (1670), Expect = 0.0, Method: Composition-based stats. Identities = 289/526 (54%), Positives = 360/526 (68%), Gaps = 10/526 (1%) Query: 24 TTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRS 83 +TA ++A+L R EE++ + A ++ H KGKLTAR RI LLD SFVELD +HR+ Sbjct: 22 STADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRT 81 Query: 84 TNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTG 143 G RP GDGVVTG+GTIDGR VC+FS D T GGS+GE +G K+VK+ + A+ G Sbjct: 82 V--EAGIPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVG 139 Query: 144 RPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTD 203 P+IGIND GARIQEGV+S+ Y+ + N+ +SGVIPQISLIMG AGG VYSPALTD Sbjct: 140 CPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTD 199 Query: 204 FVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVR 263 F +MV S MF+TGP+V+ V GE+VT E+LGG H SG AHY EQDA +V+ Sbjct: 200 FTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQ 259 Query: 264 ELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD 323 LL YLPPNN AP Y G +T+ DL LDT+IPDS Q YDM +VIT +LD Sbjct: 260 TLLGYLPPNNLDPAPVYDHDCAPG-----ITEADLALDTVIPDSEQQVYDMADVITAVLD 314 Query: 324 D-EFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFN 382 D ++LEI +A+NI+ GR++G V +VANQP H AG LDI+ASEKAARF+R CD FN Sbjct: 315 DGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFN 374 Query: 383 IPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSK 442 IP++ +DVPG+LPG QE+ GIIRRG KL YAY E+TVPKITVITRKAYGG Y VMGS+ Sbjct: 375 IPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSR 434 Query: 443 DMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNP 502 +G D +AWPTA+IAVMGA+ AV ++R++L AA E+ ++ L +Y NP Sbjct: 435 QIGADRVMAWPTAEIAVMGANSAVPILHRREL--AAVPPEERAAVKENLVDDYRRRFGNP 492 Query: 503 YVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548 Y AA GYVD VI PS TR + AL L K P +KHGN+PL Sbjct: 493 YEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 538 >1ON3-A nrPDB Length = 523 Score = 644 bits (1661), Expect = 0.0, Method: Composition-based stats. Identities = 265/525 (50%), Positives = 342/525 (65%), Gaps = 14/525 (2%) Query: 24 TTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRS 83 T G++ +L ++R+ GE VEK H++GK TARER+ LLD SF E+ A KHR+ Sbjct: 11 TMEGRVEQLAEQRQVIEAGGGERRVEKQHSQGKQTARERLNNLLDPHSFDEVGAFRKHRT 70 Query: 84 TNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTG 143 T F + + DGVVTG GTI GR V SQD TV GGS GE K+V+ E A+ TG Sbjct: 71 TLFGMDKAVVPADGVVTGRGTILGRPVHAASQDFTVMGGSAGETQSTKVVETMEQALLTG 130 Query: 144 RPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTD 203 P + D GARIQEG+ SL Y ++F N+ SGV+PQI++I G AGG YSPALTD Sbjct: 131 TPFLFFYDSGGARIQEGIDSLSGYGKMFFANVKLSGVVPQIAIIAGPCAGGASYSPALTD 190 Query: 204 FVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVR 263 F+IM + MFITGP VIK+VTGE+VT +ELGGA HMA SG H+ A + A + Sbjct: 191 FIIMTK-KAHMFITGPQVIKSVTGEDVTADELGGAEAHMAISGNIHFVAEDDDAAELIAK 249 Query: 264 ELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD 323 +LLS+LP NN+ +A P + N EL ++P + YD+ +VI +++D Sbjct: 250 KLLSFLPQNNTEEASFVN---PNNDVSPN-----TELRDIVPIDGKKGYDVRDVIAKIVD 301 Query: 324 -DEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFN 382 ++LE++AGYA N+V F R++GR VGIVANQP+ +GCLDINAS+KAA FV CD FN Sbjct: 302 WGDYLEVKAGYATNLVTAFARVNGRSVGIVANQPSVMSGCLDINASDKAAEFVNFCDSFN 361 Query: 383 IPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSK 442 IP+V LVDVPGFLPG QEY GIIR GAK+LYAY EATVPKITV+ RKAYGG+Y M ++ Sbjct: 362 IPLVQLVDVPGFLPGVQQEYGGIIRHGAKMLYAYSEATVPKITVVLRKAYGGSYLAMCNR 421 Query: 443 DMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNP 502 D+G D AWP+A+IAVMGA GA ++R+++ +D D +R +EY++ P Sbjct: 422 DLGADAVYAWPSAEIAVMGAEGAANVIFRKEI----KAADDPDAMRAEKIEEYQNAFNTP 477 Query: 503 YVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVP 547 YVAA RG VD VI P+ TR I +AL + K P KKHGN P Sbjct: 478 YVAAARGQVDDVIDPADTRRKIASALEMYATKRQTRPAKKHGNFP 522 >1X0U-A nrPDB Length = 522 Score = 640 bits (1651), Expect = 0.0, Method: Composition-based stats. Identities = 262/522 (50%), Positives = 353/522 (67%), Gaps = 13/522 (2%) Query: 29 LAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNL 88 + EL + +E++ G++ ++ H+KGKLTARER+ L D+ F E+ A R+T F L Sbjct: 12 IEELRQLKEKAYKGGGDERIQFQHSKGKLTARERLALLFDDGKFNEIMTFATTRATEFGL 71 Query: 89 GEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIG 148 ++R GDGVVTG+G +DGR V ++QD TV GGSLGE + KIV+ ELA+K G P++G Sbjct: 72 DKQRFYGDGVVTGWGKVDGRTVFAYAQDFTVLGGSLGETHANKIVRAYELALKVGAPVVG 131 Query: 149 INDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVIMV 208 IND GARIQEG +SL Y +F+ N++ASGVIPQI+++ G AAGG VYSPALTDF+IM+ Sbjct: 132 INDSGGARIQEGALSLEGYGAVFKMNVMASGVIPQITIMAGPAAGGAVYSPALTDFIIMI 191 Query: 209 DQTS-QMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELLS 267 + MF+TGP++ K V GEEV+ ++LGGA H KSG H+ EQ+A + + LLS Sbjct: 192 KGDAYYMFVTGPEITKVVLGEEVSFQDLGGAVVHATKSGVVHFMVDSEQEAINLTKRLLS 251 Query: 268 YLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLDD-EF 326 YLP NN + P P + ++ ++P+ +PY+M E+I +++D+ EF Sbjct: 252 YLPSNNMEEPPYIDTGDPA-------DRDATGVEQIVPNDAAKPYNMREIIYKIVDNGEF 304 Query: 327 LEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIV 386 LE+ +AQNI+VGF RI G VGIVAN P F G +DI+A++KAARF+R CD FNIP++ Sbjct: 305 LEVHKHWAQNIIVGFARIAGNVVGIVANNPEEFGGSIDIDAADKAARFIRFCDAFNIPLI 364 Query: 387 MLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGC 446 LVD PG++PGTDQEY GIIR GAK+LYA+ EATVPKITVI RK+YGGA+ M K +G Sbjct: 365 SLVDTPGYVPGTDQEYKGIIRHGAKMLYAFAEATVPKITVIVRKSYGGAHIAMSIKSLGA 424 Query: 447 DVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNPYVAA 506 D+ AWPTA+IAV G GAV +YR+++ + A+N +D+ K R EY NPY AA Sbjct: 425 DLVYAWPTAEIAVTGPEGAVRILYRKEI-QQASNPDDVLKQR---IAEYRKLFANPYWAA 480 Query: 507 ERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548 E+G VD VI P TR I L +L+ K PKKHGN+PL Sbjct: 481 EKGLVDDVIEPKDTRRVIVAGLEMLKTKREYRYPKKHGNIPL 522 >4Q0G-A nrPDB Length = 529 Score = 547 bits (1408), Expect = e-156, Method: Composition-based stats. Identities = 167/513 (32%), Positives = 259/513 (50%), Gaps = 30/513 (5%) Query: 29 LAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDS-FVELDALAKHRSTNFN 87 +AEL+ + + E A ++ ++GKL RER+ LLD S F+EL LA Sbjct: 20 VAELNNKLAAAALGGNERARKRHVSRGKLLPRERVDRLLDPGSPFLELAPLAA-----GG 74 Query: 88 LGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLI 147 + G G++TG G + GR I + DATV GG+ + +K ++ QE+A++ P I Sbjct: 75 MYGDESPGAGIITGIGRVSGRQCVIVANDATVKGGTYYPMTVKKHLRAQEVALQNMLPCI 134 Query: 148 GINDGAGA---RIQEGVVSLGLYSRIFRNNI-LASGVIPQISLIMGAAAGGHVYSPALTD 203 + D GA R E + RIF N +++ IPQ++ ++G+ G Y PA++D Sbjct: 135 YLVDSGGAFLPRQDEVFPDREHFGRIFYNQATMSAKGIPQVAAVLGSCTAGGAYVPAMSD 194 Query: 204 FVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVR 263 ++V + +F+ GP ++K TGE V+ EELGG H SG + A ++DA VR Sbjct: 195 EAVIVREQGTIFLGGPPLVKAATGEIVSAEELGGGDLHSRTSGVTDHLADDDEDALRIVR 254 Query: 264 ELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD 323 + P ++ P P EL ++P P PYD+HEV+ R++D Sbjct: 255 AIADTFGPCEPAQWDVRRSVEPKYP--------QAELYDVVPPDPRVPYDVHEVVVRIVD 306 Query: 324 -DEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFN 382 EF E +A Y + +V F R+ G PVGIVAN G L ++ K A F+ CD Sbjct: 307 GSEFSEFKAKYGKTLVTAFARVHGHPVGIVANN-----GVLFSESALKGAHFIELCDKRK 361 Query: 383 IPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSK 442 IP++ L ++ GF+ G D E GI + GAK++ A A VPK+TV+ +YG M + Sbjct: 362 IPLLFLQNIAGFMVGRDYEAGGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGR 421 Query: 443 DMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANG-----EDIDKLRLRLQQEYED 497 WP A+I+VMG A + + + +A G ++ + + ++ +YED Sbjct: 422 AYSPRFLWMWPNARISVMGGEQAASVLATVRGEQLSAAGTPWSPDEEEAFKAPIRAQYED 481 Query: 498 TLVNPYVAAERGYVDAVIPPSHTRGYIGTALRL 530 NPY + R + D +I P+ TR +G AL L Sbjct: 482 Q-GNPYYSTARLWDDGIIDPADTRTVVGLALSL 513 >3U9S-B nrPDB Length = 555 Score = 532 bits (1369), Expect = e-151, Method: Composition-based stats. Identities = 170/519 (32%), Positives = 253/519 (48%), Gaps = 30/519 (5%) Query: 14 RSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDS-F 72 RS E + T ++ L G A + A+GKL RERI LLD S F Sbjct: 31 RSAEFAANAATMLEQVNALRTLLGRIHEGGGSAAQARHSARGKLLVRERINRLLDPGSPF 90 Query: 73 VELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKI 132 +EL ALA H + G+V G G ++G + I DATV GG+ + +K Sbjct: 91 LELSALAAHEVYGEEVAAA-----GIVAGIGRVEGVECMIVGNDATVKGGTYYPLTVKKH 145 Query: 133 VKVQELAIKTGRPLIGINDGAGA---RIQEGVVSLGLYSRIFRNNI-LASGVIPQISLIM 188 ++ Q +A++ P I + D GA R E + RIF N +++ IPQI+++M Sbjct: 146 LRAQAIALENRLPCIYLVDSGGANLPRQDEVFPDREHFGRIFFNQANMSARGIPQIAVVM 205 Query: 189 GAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTA 248 G+ G Y PA++D +MV + + +F+ GP ++K TGE V+ EELGGA H SG A Sbjct: 206 GSCTAGGAYVPAMSDETVMVREQATIFLAGPPLVKAATGEVVSAEELGGADVHCKVSGVA 265 Query: 249 HYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSP 308 + A + A R ++ L N + Q AP P+ EL +IP Sbjct: 266 DHYAEDDDHALAIARRCVANL---NWRKQGQLQCRAPRAPLYPA-----EELYGVIPADS 317 Query: 309 NQPYDMHEVITRLLD-DEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINA 367 QPYD+ EVI RL+D EF E +A + +V GF + G P+ I+AN G L A Sbjct: 318 KQPYDVREVIARLVDGSEFDEFKALFGTTLVCGFAHLHGYPIAILANN-----GILFAEA 372 Query: 368 SEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVI 427 ++K A F+ IP++ L ++ GF+ G E GI + GAKL+ A A VPK TV+ Sbjct: 373 AQKGAHFIELACQRGIPLLFLQNITGFMVGQKYEAGGIAKHGAKLVTAVACARVPKFTVL 432 Query: 428 TRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANG-----E 482 ++G M + WP A+I VMG A G + + + +A G E Sbjct: 433 IGGSFGAGNYGMCGRAYDPRFLWMWPNARIGVMGGEQAAGVLAQVKREQAERAGQQLGVE 492 Query: 483 DIDKLRLRLQQEYEDTLVNPYVAAERGYVDAVIPPSHTR 521 + K++ + ++YE +PY ++ R + D VI P+ TR Sbjct: 493 EEAKIKAPILEQYEHQ-GHPYYSSARLWDDGVIDPAQTR 530 >5IKL-B nrPDB Length = 537 Score = 492 bits (1267), Expect = e-139, Method: Composition-based stats. Identities = 144/516 (27%), Positives = 253/516 (49%), Gaps = 24/516 (4%) Query: 34 KRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDS-FVELDALAKHRSTNFNLGEKR 92 + E+ + +A K +G+L RER+ LLD + F+EL +LA ++ + G + Sbjct: 29 RELEQKVLDKAAEARPKFEKRGQLLPRERLALLLDPGAPFLELSSLAGYKLHDDKDGTQA 88 Query: 93 PLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDG 152 G G G I G + + ++ + GG++ +K +++Q++A++ P++ + + Sbjct: 89 GGGII--AGIGYIAGVRCLVSASNSAIKGGTISPTGLKKTLRLQQIAMENKLPVVTLTES 146 Query: 153 AGARIQEGVVSLGLYSRIFRNNILAS-GVIPQISLIMGAAAGGHVYSPALTDFVIMVDQT 211 GA + +R F N S IPQ++++ G++ G Y P L+D+V++V Sbjct: 147 GGANLNYAAEIFVEGARGFANQARISAMGIPQVTVVHGSSTAGGAYQPGLSDYVVVVRGK 206 Query: 212 SQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELLSYLPP 271 ++MF+ GP ++K TGE + EELGGA H +GTA Y A + D RE++ LP Sbjct: 207 AKMFLAGPPLLKAATGEIASDEELGGAELHAQVAGTAEYLAENDADGVRLAREIVGMLPW 266 Query: 272 NNSTDA-PRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD-DEFLEI 329 N A P P P+E EL ++P P +PYD+ E++ R+ D EFL+ Sbjct: 267 NAQLPARPARSWREPLYPVE--------ELLGVVPADPKKPYDVREIVARIADGSEFLDF 318 Query: 330 QAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLV 389 + + V G RI+G G++ N G + + KAA+F++ C+ N P++ L Sbjct: 319 KNEFDGQTVCGHLRIEGHACGLIGNN-----GPITPQGAAKAAQFIQLCEQSNTPLLFLH 373 Query: 390 DVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVN 449 + GF+ GT+ E G+I+ G+K++ A A VPK+T++ +YG M + + Sbjct: 374 NTTGFMVGTESERQGVIKHGSKMIQAVANARVPKLTLVVGGSYGAGNYAMCGRGLDPRFI 433 Query: 450 LAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNPYVAAERG 509 AWP ++ AVMG + A + + A G++ D L + + ++ A G Sbjct: 434 FAWPNSRTAVMGGAQAGKVLRIVTEEKHAKEGKEADPKMLEMLETVTAQKLDSQSTALYG 493 Query: 510 ----YVDAVIPPSHTRGYIGTALRLLERKIAQLPPK 541 + D ++ P +R +G L + + P K Sbjct: 494 TASLWDDGLVDPRDSRRLLGYLLDICA-EAEARPLK 528 >3GLM-A nrPDB Length = 588 Score = 465 bits (1196), Expect = e-131, Method: Composition-based stats. Identities = 132/540 (24%), Positives = 229/540 (42%), Gaps = 66/540 (12%) Query: 30 AELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNLG 89 +++H+ +++L G + EK++ +G+L+A +RI AL+D ++ L++L + F Sbjct: 36 SDIHESIKKALD-AGITSEEKLNERGQLSAMQRINALIDPGTWCPLNSLFNPENNKFGT- 93 Query: 90 EKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGI 149 +V G G +DG+ V I + D G+ E +++ + A PLI + Sbjct: 94 ------TNIVNGLGRVDGKWVYIVASDNKKMAGAWVPGQAENLIRCSDAAKMMHLPLIYL 147 Query: 150 NDGAGARI--QEGVVS--LGLYSRIFRNNILASGVIPQISLIMG---AAAGGHVYSPALT 202 + +G Q+ V G + FRN+ L IP I I G A G H SP Sbjct: 148 LNCSGVEFPNQDKVYPNRRGGGTPFFRNSELNQLGIPVIVGIYGTNPAGGGYHSISPT-- 205 Query: 203 DFVIMVDQTSQMFITGPDVIKTVT---------GEEVTMEEL----------GGAHTHMA 243 +++ Q + M + G ++ + E++ ++ G H Sbjct: 206 --ILIAHQDANMAVGGAGILSGMNPKGYIDDEAAEQIIAAQIENSKLKVPAPGSVPIHYD 263 Query: 244 KSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTL 303 ++G + D +++ +SYLP N AP P E+ L ++ Sbjct: 264 ETGFFREVYQNDLGVIDGIKKYISYLPAYNLEFFRVDTPKAPQLPAED--------LYSI 315 Query: 304 IPDSPNQPYDMHEVITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVAN-------- 354 IP + +PYD++EVI RL D+ EF E + GY +V G +++G VG++AN Sbjct: 316 IPMNQKRPYDIYEVIARLFDNSEFSEYKKGYGPEMVTGLAKVNGLLVGVIANVQGLLMNY 375 Query: 355 -----QPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRG 409 G L K FV C IP++ L D G G + E ++ G Sbjct: 376 PEYKQNSVGIGGKLYRQGLIKMNEFVTLCARDRIPLIWLQDTTGIDVGDEAEKAELLGLG 435 Query: 410 AKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCD--VNLAWPTAQIAVMGASGAVG 467 L+Y+ + +P + + RKA A+ V+G ++ + VM A Sbjct: 436 QSLIYSIENSKLPSLEITIRKASAAAHYVLGGPQGNNTNVFSIGTGACEYYVMPGETAAN 495 Query: 468 FVYRQQLAEAAANGEDIDKLRLR---LQQEYEDTLVNPYVAAERGYVDAVIPPSHTRGYI 524 +Y ++L +A GED+ + + + Q Y D P E+G VD ++ + R YI Sbjct: 496 AMYSRKLVKAKKAGEDLQPIIGKMNDMIQMYTD-KSRPKYCTEKGMVDEIVDMTEVRPYI 554 >4L6W-A nrPDB Length = 493 Score = 465 bits (1195), Expect = e-131, Method: Composition-based stats. Identities = 197/456 (43%), Positives = 277/456 (60%), Gaps = 27/456 (5%) Query: 97 GVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGAR 156 GV+ GT++G F D TV GG++G IV + AI+ P++GI GAR Sbjct: 61 GVLAAAGTVNGVRTIAFCTDGTVMGGAMGVEGCTHIVNAYDTAIEDQSPIVGIWHSGGAR 120 Query: 157 IQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFI 216 + EGV +L ++F I ASG IPQIS+++G AAGG Y PALTD V+M + S++F+ Sbjct: 121 LAEGVRALHAVGQVFEAMIRASGYIPQISVVVGFAAGGAAYGPALTDVVVMAPE-SRVFV 179 Query: 217 TGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTD 276 TGPDV+++VTGE+V M LGG TH KSG H A E DA+D R L+ D Sbjct: 180 TGPDVVRSVTGEDVDMASLGGPETHHKKSGVCHIVADDELDAYDRGRRLVGLFCQQGHFD 239 Query: 277 APRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLDDE--FLEIQAGYA 334 + +A D ++ L+P+S + YD+ ++T +LD + F E QA +A Sbjct: 240 RSKAEAG-------------DTDIHALLPESSRRAYDVRPIVTAILDADTPFDEFQANWA 286 Query: 335 QNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGF 394 ++VVG GR+ GR VG++AN P GCL+ ++EKAARFVR CD F IP+V++VDVPG+ Sbjct: 287 PSMVVGLGRLSGRTVGVLANNPLRLGGCLNSESAEKAARFVRLCDAFGIPLVVVVDVPGY 346 Query: 395 LPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPT 454 LPG DQE+ G++RRGAKLL+A+GE TVP++T++TRK YGGAY M S+ + AWP Sbjct: 347 LPGVDQEWGGVVRRGAKLLHAFGECTVPRVTLVTRKTYGGAYIAMNSRSLNATKVFAWPD 406 Query: 455 AQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNPYVAAERGYVDAV 514 A++AVMGA AVG +++++L AAA + + L +L E+E A + G VD Sbjct: 407 AEVAVMGAKAAVGILHKKKL--AAAPEHEREALHDQLAAEHERIAGGVDSALDIGVVDEK 464 Query: 515 IPPSHTRGYIGTALRLLERKIAQLPPK--KHGNVPL 548 I P+HTR + AL AQ P + +H N+PL Sbjct: 465 IDPAHTRSKLTEAL-------AQAPARRGRHKNIPL 493 >1PIX-A nrPDB Length = 587 Score = 446 bits (1147), Expect = e-125, Method: Composition-based stats. Identities = 136/547 (24%), Positives = 224/547 (40%), Gaps = 74/547 (13%) Query: 30 AELHKRREESLHPVGEDAVE------KVHAKGKLTARERIYALLDEDSFVELDALAKHRS 83 E K+ EE +H + ++A E V+ +G+LTA +RI L++ S+ L+ L Sbjct: 28 EEQLKKIEEEIHQLIKEAQEAGKADADVNKRGELTALQRIEKLVEPGSWRPLNTL----- 82 Query: 84 TNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTG 143 FN + +V G G ++G+ + + D G+ E +++ + A Sbjct: 83 --FNPQGNKNGSVAIVKGLGRVNGKWCVVVASDNKKLAGAWVPGQAECLLRASDTAKTLH 140 Query: 144 RPLIGINDGAGARI--QEGVVS--LGLYSRIFRNNILASGVIPQISLIMG---AAAGGHV 196 PL+ + + +G + QE V G + FRN L IP I I G A G H Sbjct: 141 VPLVYVLNCSGVKFDEQEKVYPNRRGGGTPFFRNAELNQLGIPVIVGIYGTNPAGGGYHS 200 Query: 197 YSPALTDFVIMVDQTSQMFITGPDV-----------------IKTVTGEEVTMEELGGAH 239 SP VI+ + + M + G + I + E G Sbjct: 201 ISPT----VIIAHEKANMAVGGAGIMGGMNPKGHVDLEYANEIADMVDRTGKTEPPGAVD 256 Query: 240 THMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLE 299 H ++G + E+ + +++ + LP + AP P ++ Sbjct: 257 IHYTETGFMREVYASEEGVLEGIKKYVGMLPKYDPEFFRVDDPKAPAFPADD-------- 308 Query: 300 LDTLIPDSPNQPYDMHEVITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVAN---- 354 L +++P + + YD++ VI RL D+ E E + GY +V G +++G VG+VAN Sbjct: 309 LYSMVPLNDKRAYDIYNVIARLFDNSELHEYKKGYGPEMVTGLAKVNGLLVGVVANVQGL 368 Query: 355 ----------QPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNG 404 G L K FV C +PIV + D G G D E Sbjct: 369 LMNYPEYKAAGSVGIGGKLYRQGLVKMNEFVTLCARDRLPIVWIQDTTGIDVGNDAEKAE 428 Query: 405 IIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVN---LAWPTAQIAVMG 461 ++ G L+Y+ + +P+ + RK A+ V+G G D N + +IAVM Sbjct: 429 LLGLGQSLIYSIQTSHIPQFEITLRKGTAAAHYVLGGPQ-GNDTNAFSIGTAATEIAVMN 487 Query: 462 ASGAVGFVYRQQLAEAAANGED----IDKLRLRLQQEYEDTLVNPYVAAERGYVDAVIPP 517 A +Y ++LA+ G+D IDK+ +Q Y P V AE G VD ++ Sbjct: 488 GETAATAMYSRRLAKDRKAGKDLQPTIDKMNNLIQAFYT--KSRPKVCAELGLVDEIVDM 545 Query: 518 SHTRGYI 524 + RGY+ Sbjct: 546 NKIRGYV 552 >1OD4-A nrPDB Length = 805 Score = 267 bits (681), Expect = 1e-71, Method: Composition-based stats. Identities = 99/450 (22%), Positives = 172/450 (38%), Gaps = 73/450 (16%) Query: 136 QELAIKTGRPLIGINDGAGARIQEGV-VSLGLYSRIFRNNILASGVIPQISLIMGAAAGG 194 + IKT +IG DG G G + G SR + + I I+L+ + G Sbjct: 258 ERFVIKT---IIGSEDGLGVECLRGSGLIAGATSRAYHD-------IFTITLVTCRSVGI 307 Query: 195 HVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTME--ELGGAHTHMAKSGTAHYAA 252 Y L I V + + +TG I + G EV +LGG M +G +H A Sbjct: 308 GAYLVRLGQRAIQV-EGQPIILTGAPAINKMLGREVYTSNLQLGGTQI-MYNNGVSHLTA 365 Query: 253 SGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPY 312 + + + E +SY+P + P I E D +D P + ++ Y Sbjct: 366 VDDLAGVEKIVEWMSYVPAKRNMPVP----------ILETKDTWDRPVD-FTPTN-DETY 413 Query: 313 DMHEVIT----------RLLDD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAG 361 D+ +I L D F E +G+A+ +VVG R+ G P+G++ + Sbjct: 414 DVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVEN 473 Query: 362 CL-----DINASE-------------KAARFVRTCDCFN----IPIVMLVDVPGFLPGTD 399 + + N++E A + + + FN +P+++L + GF G Sbjct: 474 LIPADPANPNSAETLIQEPGQVWHPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQR 533 Query: 400 QEYNGIIRRGAKLLYAYGEATVPKITVI--TRKAYGGAYCVM------GSKDMGCDVNLA 451 +N +++ G+ ++ A + P I I T + GG++ V+ +M DVN Sbjct: 534 DMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVN-- 591 Query: 452 WPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNPYVAAERGYV 511 A+ V+ G VG +R++ N D LR Q + + + Sbjct: 592 ---ARAGVLEPQGMVGIKFRREKLLDTMNRLDDKYRELRSQLSNKSLAPEVHQQISKQLA 648 Query: 512 DAVIPPSHTRGYIGTALRLLERKIAQLPPK 541 D G I L + +++ K Sbjct: 649 DRERELLPIYGQISLQFADLHDRSSRMVAK 678 >2F9Y-A nrPDB Length = 339 Score = 173 bits (437), Expect = 2e-43, Method: Composition-based stats. Identities = 61/215 (28%), Positives = 90/215 (41%), Gaps = 21/215 (9%) Query: 308 PNQPYDMHEVITRLLDDEFLEIQA--GYAQN--IVVGFGRIDGRPVGIVANQPTHFA--- 360 P +PY + V RL DEF E+ YA + IV G R+DGRPV I+ +Q Sbjct: 90 PQRPYTLDYV--RLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEK 147 Query: 361 -----GCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYA 415 G KA R ++ + F +PI+ +D PG PG E G A+ L Sbjct: 148 IRRNFGMPAPEGYRKALRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLRE 207 Query: 416 YGEATVPKI-TVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQ-Q 473 VP + TVI GGA + +G VN+ + +V+ G +++ Sbjct: 208 MSRLGVPVVCTVIGEGGSGGALAI----GVGDKVNM-LQYSTYSVISPEGCASILWKSAD 262 Query: 474 LAEAAANGEDIDKLRLRLQQEYEDTLVNPYVAAER 508 A AA I + RL+ + + + P A R Sbjct: 263 KAPLAAEAMGIIRPRLKELKLIDSIIPEPLGGAHR 297 Score = 62.1 bits (149), Expect = 6e-10, Method: Composition-based stats. Identities = 56/293 (19%), Positives = 94/293 (32%), Gaps = 60/293 (20%) Query: 21 DIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAK 80 ++H K EL ++ L + + + R+ +F E D LA Sbjct: 59 EVHRLREKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRL-------AFDEFDELAG 111 Query: 81 HRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDA--------TVFGGSLGEVYGEKI 132 R+ + +V G +DGR V I G K Sbjct: 112 DRAYADDK--------AIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKA 163 Query: 133 VKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRN-NILASGVIPQISLIMGAA 191 +++ ++A + P+I D GA G G I RN ++ +P + ++G Sbjct: 164 LRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEG 223 Query: 192 AGGHVYSPALTDFVIMVD--------------------QTSQ-----MFITGPDVIKTVT 226 G + + D V M+ + M I P + + Sbjct: 224 GSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIRPRLKELKL 283 Query: 227 GEEVTMEELGGAHTH---MAKSGTAHYAAS-GEQDAF-------DYVRELLSY 268 + + E LGGAH + MA S A A + D + L+SY Sbjct: 284 IDSIIPEPLGGAHRNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSY 336 >2F9Y-B nrPDB Length = 304 Score = 168 bits (426), Expect = 4e-42, Method: Composition-based stats. Identities = 65/262 (24%), Positives = 104/262 (39%), Gaps = 40/262 (15%) Query: 56 KLTARERIYALLDEDSFVEL-------DALAKHRSTNFNL-----GEKRPLGDGVVTGYG 103 ++TAR R+++LLDE S VEL D L S + ++ D +V G Sbjct: 54 RMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKG 113 Query: 104 TIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVS 163 T+ G V + + GGS+G V G + V+ E A++ PLI + GAR+QE ++S Sbjct: 114 TLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMS 173 Query: 164 LGLYSRIFRNNILAS-GVIPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVI 222 L ++ +P IS++ GG S A+ + + + + + GP VI Sbjct: 174 LMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVI 233 Query: 223 KTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELLSY-------------L 269 + E++ G E+ A D + L Sbjct: 234 EQTVREKLP-------------PGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNL 280 Query: 270 PPNNSTDAPRYQAAAPTGPIEE 291 P N +APR P P +E Sbjct: 281 PAPNP-EAPREGVVVPPVPDQE 301 >5KDR-B nrPDB Length = 285 Score = 153 bits (385), Expect = 3e-37, Method: Composition-based stats. Identities = 51/187 (27%), Positives = 82/187 (43%), Gaps = 10/187 (5%) Query: 57 LTARERIYALLDEDSFVELD-ALAKHRSTNF--------NLGEKRPLGDGVVTGYGTIDG 107 LTA +RI A+ DE SF E D + +F +K L + VVTG +DG Sbjct: 61 LTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDG 120 Query: 108 RDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLY 167 + D+ GS+G V GEKI ++ + + P I + GAR+QEG++SL Sbjct: 121 MKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQM 180 Query: 168 SRIFRNNILAS-GVIPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVT 226 + + S + IS + GG S A + + + + + G VI+ Sbjct: 181 GKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTI 240 Query: 227 GEEVTME 233 E++ + Sbjct: 241 NEKLPDD 247 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 44/272 (16%), Positives = 86/272 (31%), Gaps = 31/272 (11%) Query: 259 FDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVI 318 Y +EL L + D A + + + P D + Sbjct: 39 IMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSAN---PLDFPSYL 95 Query: 319 TRLLDDEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTC 378 ++ E + + G + +V G ++DG G+ G + EK R + C Sbjct: 96 EKI---EKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYC 152 Query: 379 DCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCV 438 +P ++ G + + + L + +A + I+ +T GG Sbjct: 153 TENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSAS 212 Query: 439 MGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDT 498 S D+NL+ P A I G R+ + + + ++ D Sbjct: 213 FASVG---DINLSEPKALIGFAG---------RRVIEQT-------------INEKLPDD 247 Query: 499 LVNPYVAAERGYVDAVIPPSHTRGYIGTALRL 530 E G +D V+ + R + L++ Sbjct: 248 FQTAEFLLEHGQLDKVVHRNDMRQTLSEILKI 279 >5VJ1-D nrPDB Length = 287 Score = 146 bits (369), Expect = 2e-35, Method: Composition-based stats. Identities = 66/264 (25%), Positives = 104/264 (39%), Gaps = 20/264 (7%) Query: 56 KLTARERIYALLDEDSFVEL-DALAKHRSTNFNLGEKRPLGD-GVVTGYGTIDGRDVCIF 113 +L AR+R ALLD SF EL D A +S P D GVV G +DG+ + Sbjct: 15 ELGARQRARALLDAGSFRELLDPFAGVQSPWLERQGIVPQADDGVVVARGLLDGQPAVLA 74 Query: 114 SQDATVFGGSLGEVYGEKIVKVQELAIKTGRP-----LIGINDGAGARIQEGVVSLGLYS 168 + + GGSLGEV G KI ELA + R + + + G R+QE + L + Sbjct: 75 AIEGAFQGGSLGEVSGAKIAGALELAAEDNRNGVPTRALLLLETGGVRLQEANLGLAAIA 134 Query: 169 RIFRNNILASGVIPQISLIMGA--AAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVT 226 I + P +++I G GG + L +V++ + +++ + GP VI+ Sbjct: 135 EIQAAIVDLQRYQPVVAVIAGPVGCFGGMSIAAGLCSYVLVTRE-ARLGLNGPQVIEQEA 193 Query: 227 GEEVTME-------ELGGAHTHMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPR 279 G L G SG A + + D +L+Y Sbjct: 194 GIAEYDSRDRPFIWSLTGGE-QRFASGLADAYLADDLDEVR--TSVLAYFAKGLPARPRC 250 Query: 280 YQAAAPTGPIEENLTDEDLELDTL 303 +A + + T E + + Sbjct: 251 RRAEDYLRRLGDLDTAEQPDAAGV 274 >5KDR-A nrPDB Length = 327 Score = 110 bits (274), Expect = 2e-24, Method: Composition-based stats. Identities = 41/214 (19%), Positives = 73/214 (34%), Gaps = 19/214 (8%) Query: 308 PNQPYDMHEVITRLLDDEFLEIQAGY----AQNIVVGFGRIDGRPVGIVANQPTHFA--- 360 +P + + + D F+E+ ++ G G ++GR V ++ Q Sbjct: 76 QERPTTLDYIPY--IFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDN 133 Query: 361 -----GCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYA 415 G KA R ++ + FN PI +D G PG E G A L Sbjct: 134 IYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIE 193 Query: 416 YGEATVPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYR-QQL 474 VP I ++ + + L + +V+ GA +++ L Sbjct: 194 MASLKVPVIAIVIGEGG----SGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNL 249 Query: 475 AEAAANGEDIDKLRLRLQQEYEDTLVNPYVAAER 508 A+ AA I ++ +D + P A + Sbjct: 250 AKIAAETMKITAHDIKQLGIIDDVISEPLGGAHK 283 Score = 49.4 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 52/249 (20%), Positives = 90/249 (36%), Gaps = 37/249 (14%) Query: 19 TIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDAL 78 +I L K+ +L P + ++ + T + I + D SF+EL Sbjct: 43 QEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERP--TTLDYIPYIFD--SFMEL--- 95 Query: 79 AKHRSTNFNLGEKRPLGDGVVTGYG-TIDGRDVCIFSQDATVFG-GSLGEVYGEKIVKVQ 136 H NF G G + G T+ G+ ++D G K +++ Sbjct: 96 --HGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLM 153 Query: 137 ELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRN-NILASGVIPQISLIMGAAAGGH 195 + A K RP+ D GA + G I N +AS +P I++++G G Sbjct: 154 KQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGG 213 Query: 196 VYSPALTDFVIMVDQTSQ-------------------------MFITGPDVIKTVTGEEV 230 + + V+M++ ++ M IT D+ + ++V Sbjct: 214 ALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDV 273 Query: 231 TMEELGGAH 239 E LGGAH Sbjct: 274 ISEPLGGAH 282 >5VIP-A nrPDB Length = 284 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 36/162 (22%), Positives = 54/162 (33%), Gaps = 21/162 (12%) Query: 339 VGFGRIDGRPVGIVANQP----------THFAGCLDINASEKAARFVRTCDC---FNIPI 385 V +DG PV +A P G L+ A D + Sbjct: 48 VADAELDGYPVRFLAVVPDPDNPFPRARQGEVGLLEGWGLAAAVDEALEADREAPRKRAL 107 Query: 386 VMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATV---PKITVITRKAYGGAYCVMGSK 442 + +VDVP G +E GI + A + AY A + P I ++ KA GA+ Sbjct: 108 LAIVDVPSQAYGRREEALGIHQALAGAVDAYARARLAGHPLIGLLVGKAMSGAFLA---H 164 Query: 443 DMGCDVNLAW--PTAQIAVMGASGAVGFVYRQQLAEAAANGE 482 + +A P + MG + A R A + Sbjct: 165 GYQANRLIALHDPGVMVHAMGKAAAARITLRSVEELEALAAK 206 >1O9J-A nrPDB Length = 501 Score = 36.7 bits (83), Expect = 0.030, Method: Composition-based stats. Identities = 50/304 (16%), Positives = 80/304 (26%), Gaps = 31/304 (10%) Query: 237 GAHTHMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDE 296 T A RE P + DA + + + + Sbjct: 42 NPATEEKICEVEEADKEDVDKAVKAAREAFQMGSPWRTMDASER--GQLIYKLADLIERD 99 Query: 297 DLELDTLIPDSPNQPY------DMHEVITRLLDDEFLEIQAGYAQNIVVGFGRIDGRPVG 350 L L TL + + + D+ I L AG+A I +DG Sbjct: 100 RLLLATLESINAGKVFASAYLMDLDYCIKAL------RYCAGWADKIQGRTIPVDGEFFS 153 Query: 351 IVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGA 410 ++P G + A + P + + P + A Sbjct: 154 YTRHEPIGVCGLIFPWN----APMILLACKIG-PALCCGNTVIVKPAEQTPLTAL--HVA 206 Query: 411 KLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAV-GFV 469 L+ EA P V YG S M D + ++ M A + Sbjct: 207 SLI---KEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKMIQEAAAKSNL 263 Query: 470 YRQQLAEAAANG------EDIDKLRLRLQQEYEDTLVNPYVAAERGYVDAVIPPSHTRGY 523 R L A N D+D Q +AA + +V+ I + Sbjct: 264 KRVTLELGAKNPCIVFADADLDSAVEFAHQGVFTNQGQSCIAASKLFVEEAIYDEFVQRS 323 Query: 524 IGTA 527 + A Sbjct: 324 VERA 327 >2PG0-A nrPDB Length = 385 Score = 33.2 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 53/154 (34%), Gaps = 23/154 (14%) Query: 385 IVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDM 444 +V+ D PGF G E G+ + L+ + +A VP ++ + G Y +M Sbjct: 190 LVVERDTPGFTRGRKLEKVGLHAQDTAELF-FQDAKVPAYNLLGEEGKG-FYYLMEKLQ- 246 Query: 445 GCDVNLAWPTAQIAVMGASGAVGFVYR------QQLAEAAANGEDIDKLRLRLQQEYEDT 498 + + A A ++ +Q + ++ RL + + Sbjct: 247 --------QERLVVAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQFRLAEMATEI 298 Query: 499 LVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLE 532 A R +VD VI I T + + + Sbjct: 299 ------ALGRTFVDRVIEEHMAGKQIVTEVSMAK 326 >5Y6T-A nrPDB Length = 387 Score = 31.7 bits (70), Expect = 0.81, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 37/99 (37%), Gaps = 12/99 (12%) Query: 345 DGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNG 404 +G VG A A+F+ N+ +V +V G T Y Sbjct: 83 NGYVVGTDAQNTMT----------SDLAQFLDVAYANNV-LVFIVLWNGATTPT-SRYRD 130 Query: 405 IIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKD 443 +I +KL +A VP ++ ++ K G + VM + Sbjct: 131 LIYDDSKLQTYIDQALVPMVSALSGKVALGGWEVMNEPE 169 >2E7J-A nrPDB Length = 371 Score = 31.7 bits (70), Expect = 0.88, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 36/99 (36%), Gaps = 15/99 (15%) Query: 411 KLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVY 470 K+ E VP ++ AY + K++G D + +A G G +G Sbjct: 168 KIAKVCSEYDVP---LLVNGAYAIGRMPVSLKEIGADFIVGSGHKSMAASGPIGVMGMK- 223 Query: 471 RQQLAEAAANGEDIDKLRLRLQQEYEDTLVNPYVAAERG 509 E+ ++ LR ++Y++ V RG Sbjct: 224 -----------EEWAEIVLRRSEKYKNKEVELLGCTARG 251 >4PY5-A nrPDB Length = 271 Score = 31.7 bits (70), Expect = 0.88, Method: Composition-based stats. Identities = 28/152 (18%), Positives = 53/152 (34%), Gaps = 9/152 (5%) Query: 195 HVYSPALTDFVIMVDQTSQMFITGPD--VIKTVTGEEV-TMEELGGAHTHMAKSGTAHYA 251 Y L D ++ V ++ + G +K + E V + EL ++G + Sbjct: 30 AQYRLRLNDAILTVYKSGSVVYGGKGREKLKELVAETVLSDTEL--PRIGCNEAGKGEFV 87 Query: 252 ASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQP 311 + L L D+ + E ++ LIP+ N+ Sbjct: 88 GPLVVACIVADEKCLKRLIELGVKDSKKLSNEKVEELASEITETCHGKVKLLIPEKYNRA 147 Query: 312 YDMHEVITRLLDDEFLEIQAG----YAQNIVV 339 Y + I RLL+ + EI + ++ +VV Sbjct: 148 YSKFKNINRLLEAVYREIVSDLCEKFSPKVVV 179 >2ZYA-A nrPDB Length = 480 Score = 31.7 bits (70), Expect = 0.91, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 19/47 (40%), Gaps = 2/47 (4%) Query: 392 PGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCV 438 P +PG +E ++ + A E P +T I A G + V Sbjct: 150 PSIMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYI--GADGAGHYV 194 >4DYD-A nrPDB Length = 283 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 38/174 (21%), Positives = 66/174 (37%), Gaps = 13/174 (7%) Query: 350 GIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPI----VMLVDVPGFLPGTDQEYNGI 405 G+ A AG D A++KA +R D + +++ VP L Y + Sbjct: 49 GLAAVYEKEVAGAAD-GAAQKALGGIRYSDDLAQAVKDADLVIEAVPESLDLKRDIYTKL 107 Query: 406 IRRG-AKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASG 464 AK ++A +T+ ++ G + + N W VMG + Sbjct: 108 GELAPAKTIFATNSSTLLPSDLVGYTGRGDKFLALHF------ANHVWVNNTAEVMGTTK 161 Query: 465 AVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNPYV-AAERGYVDAVIPP 517 VY+Q + A+A G +L+ ++L+ P + AA VD + P Sbjct: 162 TDPEVYQQVVEFASAIGMVPIELKKEKAGYVLNSLLVPLLDAAAELLVDGIADP 215 >4HST-B nrPDB Length = 543 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 37/186 (19%), Positives = 61/186 (32%), Gaps = 28/186 (15%) Query: 377 TCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAY 436 CD F++ + + VPGF K+ Y A + + + G Sbjct: 38 ACDRFDMIGLTVPGVPGFPS---------FAHNGKVAYCVTSAFMDIHDLYLEQFAGEGR 88 Query: 437 CVMGSKDMGCDVNLAWPTAQIAVMGASG-AVGFVYRQQLAEAAANGEDIDKLRLRLQQEY 495 D +AW +IAV G + V + A + D L LR Q Sbjct: 89 TARFGNDFEP---VAWSRDRIAVRGGADREFDIVETRHGPVIAGDPRDGAALTLRSVQFA 145 Query: 496 EDTLV-------------NPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKK 542 E L A RG+ +I + G + ++ L R P++ Sbjct: 146 ETDLSFDCLTRMPGASTVAQLYDATRGW--GLIDHNLVAGDVAGSIGHLVRARVPSRPRE 203 Query: 543 HGNVPL 548 +G +P+ Sbjct: 204 NGWLPV 209 >4JCS-A nrPDB Length = 286 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 42/110 (38%), Gaps = 18/110 (16%) Query: 402 YNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAV-- 459 + I+ G + ++ P I + A+G + + + D+ LA P A+ ++ Sbjct: 101 WQQRIKTGLRFIHDMLNLGRPVIAAVDGPAFGAGFAL----SLTADIVLASPRARFSMAY 156 Query: 460 --------MGA----SGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYED 497 +GA AVG ++L + + + RL L E + Sbjct: 157 LRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEAHRLGLVMEVHE 206 >5NNZ-B nrPDB Length = 415 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 21/44 (47%) Query: 58 TARERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVTG 101 + +R L D S EL+ L HR+ + + P GD + TG Sbjct: 110 GSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATG 153 >4JWV-A nrPDB Length = 278 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 29/83 (34%), Gaps = 5/83 (6%) Query: 146 LIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFV 205 IG + GA L + P ++ + G GG + A+ + Sbjct: 83 CIGADVSGGAE--RKTRMALGGGLTGIGGPLVTCKKPMVAAVQGFCVGGG-FELAMCADI 139 Query: 206 IMVDQTSQMFITGPDVIKTVTGE 228 I+ T+Q + P+ + GE Sbjct: 140 IVAADTAQFGL--PETKVGIIGE 160 >5W8P-A nrPDB Length = 370 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 36/257 (14%), Positives = 79/257 (30%), Gaps = 32/257 (12%) Query: 50 KVHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRD 109 V + G+L+ R R + + + + G +G++ ID Sbjct: 33 AVQSWGELSPR-RDNVVFVCHALTADSHVVGPAGPDHITGG---WWEGIIGPGAAIDTDH 88 Query: 110 VCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSR 169 C + + V GG G + + G+P G+R E V + + Sbjct: 89 WCAVATN--VLGGCRGTTGPTSLAR-------DGKPW-------GSRFPEVSVRDQVNAD 132 Query: 170 IFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEE 229 + LA I +++ ++G + GG ++ +M + + V TG++ Sbjct: 133 V---AALAQLGITEVAAVVGGSMGGA----RALEWAVMHPDAVRAALVLA-VGARATGDQ 184 Query: 230 VTMEELGGAHTHMA---KSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPT 286 + + A + G H + + R +++L + P Sbjct: 185 IGTQSTQIAAIQTDPDWQGGDYHGSGRSPGKGLNLARR-IAHLTYRGEVELDTRFGNDPQ 243 Query: 287 GPIEENLTDEDLELDTL 303 + + Sbjct: 244 VGPDGPEDPWADGRYAV 260 >4K1W-A nrPDB Length = 418 Score = 30.5 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 20/50 (40%) Query: 151 DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA 200 G+ I E V ++G Y + I A +P I G G Y PA Sbjct: 138 HANGSDIAETVEAVGHYIDMGYKAIRAQTGVPGIKDAYGVGRGKLYYEPA 187 >4Q1V-A nrPDB Length = 710 Score = 30.1 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 35/256 (13%), Positives = 79/256 (30%), Gaps = 46/256 (17%) Query: 7 RSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDA-----VEKVHAKGKLTARE 61 RS H A ++ + GK+++ + +ES H A +++ K + Sbjct: 381 RSGHFA---------VNVSNGKISQPFENCKESEHSGTLSASGTYLIDRYSTKDQ----P 427 Query: 62 RIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDAT--- 118 R+ L+D +F E L + + GT D + + Sbjct: 428 RVINLVDTKNFKETANLLTAENPYDGYQMPSIETGTIKAADGTTDLHYRLMKPANFDPAK 487 Query: 119 -------VFGG---SLGEVYGEKIVKVQELAIKTGRPLIGINDGAGAR-----IQEGVVS 163 V+GG + + + + + ++ D G+ + Sbjct: 488 KYPVIVYVYGGPHAQCVTGGWQNGARGWDTYMASKGYIMFTIDNRGSSNRGLTFENATFR 547 Query: 164 LGLY--SRIFRNNILASGVIPQI----SLIMGAAAGGHVYSPALTDFVIMVDQTSQMFIT 217 + + +P + + G + GGH+ + + + + ++ + Sbjct: 548 RLGIEEGKDQVKGVEFLKSLPYVDSERIGVHGWSFGGHMTTALMLRY----PEIFKVGVA 603 Query: 218 GPDVIKTVTGEEVTME 233 G VI E + E Sbjct: 604 GGPVIDWGYYEIMYGE 619 >4HJH-A nrPDB Length = 481 Score = 30.1 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 36/193 (18%), Positives = 59/193 (30%), Gaps = 19/193 (9%) Query: 77 ALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQ 136 AL P + T + V F + V GS E G + Sbjct: 289 ALESRFPKVLRTRVGSPYVIASMAQVSTGNSGPVIGFEANGGVLLGSTVERNGRSL---- 344 Query: 137 ELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHV 196 A+ T L+ I A + E L +R + + S + I Sbjct: 345 -TALPTRDALLPILACL-ATVHEKKTPLSTIARSYGFRVALSDRLQNI-----PQEASTA 397 Query: 197 YSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAH----YAA 252 + L D D+ + +F G +++ T + V + G H SG A Y Sbjct: 398 FLALLED----ADKRASLFPAGDAIVRVETIDGVKLFFQSGNAVHYRASGNAPELRCYVE 453 Query: 253 SGEQDAFDYVREL 265 S + ++ L Sbjct: 454 SSDDTQAAKLQAL 466 >4IS3-A nrPDB Length = 268 Score = 29.8 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 24/172 (13%), Positives = 51/172 (29%), Gaps = 11/172 (6%) Query: 17 EHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARE--RIYALLDEDSFVE 74 E ++ T +L EL+ E + + V A A++ R+ +++ Sbjct: 57 ETQEEVDTALAQLKELYPEEEVLGFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITS 116 Query: 75 LDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVK 134 + ++ F + G +G G + I Sbjct: 117 NNVFSRVSEEEFKHIMD-------INVTGVFNGAWCAYQCMKDAKKGVIINTASVTGIFG 169 Query: 135 VQELA--IKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQI 184 + +IG+ G G I + + + N + +G P+I Sbjct: 170 SLSGVGYPASKASVIGLTHGLGREIIRKNIRVVGVAPGVVNTDMTNGNPPEI 221 >2YRI-A nrPDB Length = 353 Score = 29.8 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 37/231 (16%), Positives = 68/231 (29%), Gaps = 27/231 (11%) Query: 34 KRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNLGEKRP 93 +R +++L ++ + +ER+ AL D + ALA S G Sbjct: 13 ERVQKALLRPMRGHLDPEVLRVNRAIQERLAALFDPGEGALVAALAGSGSLGMEAGLANL 72 Query: 94 LGDGVVTGYGTIDGRDVCIFSQDATVFGGSLG------------EVYGEKIVKVQELAIK 141 V+ ++G FSQ G V E + + + Sbjct: 73 DRGPVLV---LVNG----AFSQRVAEMAALHGLDPEVLDFPPGEPVDPEAVARALKRRRY 125 Query: 142 TGRPLIGINDGAGA-RIQE--GVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYS 198 L+ G E G ++ + F + + G++P A G Y+ Sbjct: 126 RMVALVHGETSTGVLNPAEAIGALAKEAGALFFLDAVTTLGMLP-----FSMRAMGVDYA 180 Query: 199 PALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAH 249 + + + K TG+ +L H + G H Sbjct: 181 FTGSQKCLSAPPGLAPIAASLEARKAFTGKRGWYLDLARVAEHWERGGYHH 231 >5H9U-C nrPDB Length = 413 Score = 29.4 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 22/149 (14%), Positives = 50/149 (33%), Gaps = 12/149 (8%) Query: 207 MVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELL 266 +++ + + + GP +TG ++ ++ GGA H + + ++ A Y R + Sbjct: 254 LINPSGRFILGGPHADTGLTGRKIIVDTYGGAVPHGGGAFSGKDPTKVDRSASYYARYMA 313 Query: 267 SYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD--- 323 + + A G + ++PD + E+ ++ D Sbjct: 314 KNIVAAGLARRALVELAYAIGKARPVSLRVETFGTGVLPDEK-----LTEIAKKVFDPRP 368 Query: 324 ----DEFLEIQAGYAQNIVVGFGRIDGRP 348 +E ++ Y G G P Sbjct: 369 LAIIEELDLLRPIYTPTSAYGHFGRPGFP 397 >4IZC-A nrPDB Length = 275 Score = 29.0 bits (63), Expect = 6.0, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 42/116 (36%), Gaps = 16/116 (13%) Query: 174 NILASGVIPQISLIMGAAAGGHVYSPALTDFVIM-------VDQTSQMFITGPDV---IK 223 N + G +P I+ + GA GG + + +M + + + TG + Sbjct: 98 NKMEYGGVPIIAALRGAVVGGGLALASAAHLRVMDQSTYFALPEGQRGIFTGGGATIRVS 157 Query: 224 TVTGEEVTMEELGGAHTH----MAKSGTAHYAASGE--QDAFDYVRELLSYLPPNN 273 + G+ ++ + + A G A Y G A + ++ S LP N Sbjct: 158 DMIGKYRMIDMILTGRVYQGQEAADLGLAQYITEGSSFDKAMELADKIASNLPLTN 213 >5T12-A nrPDB Length = 255 Score = 28.6 bits (62), Expect = 8.2, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 35/103 (33%), Gaps = 13/103 (12%) Query: 413 LYAYGEATVPK---ITVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFV 469 L A A +P+ + V+ R + + + +G VMGA + Sbjct: 161 LSATTLAELPQDRLVGVVVRDGAANSQAAIMVRALGIPT----------VMGADIQPSVL 210 Query: 470 YRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNPYVAAERGYVD 512 +R+ L GE + L QEY+ + + D Sbjct: 211 HRRTLIVDGYRGELLVDPEPVLLQEYQRLISEEIELSRLAEDD 253 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.124 0.306 Lambda K H 0.267 0.0385 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,309,999 Number of Sequences: 36641 Number of extensions: 717027 Number of successful extensions: 2249 Number of sequences better than 10.0: 43 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 2036 Number of HSP's gapped (non-prelim): 79 length of query: 548 length of database: 10,336,785 effective HSP length: 102 effective length of query: 446 effective length of database: 6,599,403 effective search space: 2943333738 effective search space used: 2943333738 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.2 bits)