BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P9WP55 (310 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2Q3D-A nrPDB 618 e-178 4I1Y-A nrPDB 510 e-145 4LMA-A nrPDB 385 e-107 4LMB-A nrPDB 379 e-106 5XA2-A nrPDB 358 1e-99 4AEC-A nrPDB 356 6e-99 2ISQ-A nrPDB 335 1e-92 2EGU-A nrPDB 320 6e-88 3VBE-A nrPDB 313 5e-86 5J5V-A nrPDB 309 1e-84 2PQM-A nrPDB 293 5e-80 3T4P-A nrPDB 290 7e-79 3FCA-A nrPDB 284 3e-77 5XCN-X nrPDB 278 2e-75 5XEM-A nrPDB 274 3e-74 2EFY-A nrPDB 259 9e-70 3X43-A nrPDB 247 5e-66 5XW3-A nrPDB 243 7e-65 6AHI-A nrPDB 243 7e-65 2JC3-A nrPDB 235 2e-62 4OFX-A nrPDB 233 7e-62 1M54-A nrPDB 233 7e-62 4COO-A nrPDB 233 1e-61 5MMS-A nrPDB 232 2e-61 2BHS-A nrPDB 230 5e-61 5B1I-A nrPDB 224 4e-59 3PC3-A nrPDB 221 2e-58 5OHX-A nrPDB 218 2e-57 6C2H-A nrPDB 191 3e-49 5JJC-A nrPDB 186 1e-47 5I7O-A nrPDB 173 8e-44 5B55-A nrPDB 170 7e-43 5D84-A nrPDB 148 3e-36 3VSD-A nrPDB 83 2e-16 5X2L-A nrPDB 61 6e-10 3L6C-A nrPDB 50 1e-06 1TDJ-A nrPDB 50 1e-06 6NMX-A nrPDB 47 1e-05 6HUL-B nrPDB 44 8e-05 5EY5-B nrPDB 42 3e-04 3IAU-A nrPDB 41 5e-04 5OCW-B nrPDB 41 8e-04 4NEG-A nrPDB 37 0.007 2D1F-A nrPDB 37 0.012 6AMI-A nrPDB 36 0.018 5KIN-B nrPDB 35 0.041 5YGR-A nrPDB 34 0.072 5YBW-A nrPDB 34 0.077 1VE5-A nrPDB 34 0.082 1X1Q-A nrPDB 34 0.10 5C3U-A nrPDB 33 0.11 1V71-A nrPDB 33 0.18 4CNG-A nrPDB 32 0.30 5CVC-A nrPDB 32 0.36 2ZSJ-A nrPDB 31 0.56 3DAH-A nrPDB 31 0.80 3PZD-A nrPDB 30 1.3 2GN1-A nrPDB 30 1.6 1BWR-A nrPDB 29 2.2 1UIN-A nrPDB 28 3.4 3R0X-A nrPDB 28 5.3 >2Q3D-A nrPDB Length = 313 Score = 618 bits (1594), Expect = e-178, Method: Compositional matrix adjust. Identities = 310/310 (100%), Positives = 310/310 (100%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL Sbjct: 4 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 63 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD Sbjct: 64 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 123 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG Sbjct: 124 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 183 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI Sbjct: 184 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 243 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL Sbjct: 244 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 303 Query: 301 STPLFADVAD 310 STPLFADVAD Sbjct: 304 STPLFADVAD 313 >4I1Y-A nrPDB Length = 314 Score = 510 bits (1314), Expect = e-145, Method: Compositional matrix adjust. Identities = 263/310 (84%), Positives = 290/310 (93%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 M+IAE+I QLIG TPLVRLRRVTDGA AD+VAKLE FNPA S+KDRIGVAM+ AAE+AGL Sbjct: 5 MTIAENIAQLIGGTPLVRLRRVTDGAAADVVAKLESFNPAGSIKDRIGVAMIDAAEKAGL 64 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 IKPDTIILEPTSGNTGIALAMV AARGY+CVLTMP+TMS+ERRMLLRAYGAEL+LTPGA+ Sbjct: 65 IKPDTIILEPTSGNTGIALAMVSAARGYKCVLTMPDTMSIERRMLLRAYGAELVLTPGAE 124 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM+GAIAKAEELAKTD RYF+PQQFENPANPA+H VTTAEEVWRDTDGKVDI V+GVGTG Sbjct: 125 GMAGAIAKAEELAKTDDRYFIPQQFENPANPAVHAVTTAEEVWRDTDGKVDIFVSGVGTG 184 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GTITGVAQVIK+R+PSA+FVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLD LVDE+ Sbjct: 185 GTITGVAQVIKQRRPSAQFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDLALVDEV 244 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 ITVGN+DAL +ARR+A EEGLL GISSGAA AA ++A RPENAGKLIVVVLPDFGERYL Sbjct: 245 ITVGNDDALELARRMATEEGLLFGISSGAAVWAARELAHRPENAGKLIVVVLPDFGERYL 304 Query: 301 STPLFADVAD 310 ST LFAD+++ Sbjct: 305 STVLFADLSE 314 >4LMA-A nrPDB Length = 326 Score = 385 bits (989), Expect = e-107, Method: Compositional matrix adjust. Identities = 201/313 (64%), Positives = 249/313 (79%), Gaps = 3/313 (0%) Query: 1 MSIAEDITQLIGRTPLVRLRRV--TDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQA 58 M IA D+T+L+GRTPLV+L R+ +G + IV KLE NPA SVKDRIG M+ +AE+A Sbjct: 8 MRIAHDVTELVGRTPLVQLNRIPQAEGCLGRIVMKLEGMNPAASVKDRIGTHMINSAEKA 67 Query: 59 GLIKPDTIIL-EPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTP 117 GLI P+T +L EPTSGNTGIALAM AA+GYR +LTMPETMSLERR +L+AYGA L LTP Sbjct: 68 GLINPETTVLVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELTP 127 Query: 118 GADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 G+ GM GAI +A+++ + ++ QQF NP+NP IHR+TTAEE+W+DT+G+VD +VAGV Sbjct: 128 GSQGMKGAILRAQQIVDSIPGAYMLQQFRNPSNPEIHRLTTAEEIWQDTEGQVDFIVAGV 187 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLV 237 GTGGTITGVA+VIK RKPS + VAVEP SPV+SGG GPH IQGIGAGF+P VL DL+ Sbjct: 188 GTGGTITGVAEVIKSRKPSFQVVAVEPFNSPVISGGNPGPHKIQGIGAGFIPEVLRTDLI 247 Query: 238 DEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGE 297 DE+ITV +E+A RRLA+EEGLL GISSGA AA+Q+A+RPEN GKLIVV+ P FGE Sbjct: 248 DEVITVSDEEAFQFGRRLAKEEGLLSGISSGANLCAAIQLAQRPENEGKLIVVIQPSFGE 307 Query: 298 RYLSTPLFADVAD 310 RYLST +F ++ + Sbjct: 308 RYLSTLMFQNIEE 320 >4LMB-A nrPDB Length = 322 Score = 379 bits (973), Expect = e-106, Method: Compositional matrix adjust. Identities = 207/313 (66%), Positives = 246/313 (78%), Gaps = 3/313 (0%) Query: 1 MSIAEDITQLIGRTPLVRLRR--VTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQA 58 M IA DITQL+GRTPLV+L R V +G A IV KLE NPA SVKDRIGV+M++ AE A Sbjct: 8 MLIARDITQLVGRTPLVQLNRIPVAEGVKARIVVKLESMNPAASVKDRIGVSMVEDAEAA 67 Query: 59 GLIKPD-TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTP 117 GLI PD TI++EPTSGNTGIALAMV AA+GYR VLTMPETMSLERR +L+AYGA+L LTP Sbjct: 68 GLIHPDKTILVEPTSGNTGIALAMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELTP 127 Query: 118 GADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 G+ GM GAI +AEE+ + + QQF NPANP IHR TTAEE+W DTDG VDIV+ GV Sbjct: 128 GSQGMEGAITRAEEIVENTPNAYSLQQFRNPANPKIHRETTAEEIWADTDGLVDIVIGGV 187 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLV 237 GTGGTITG+A+ IK R+P + +AVEP+ SPVLSGGQ GPH IQGIGAGF+P + +L+ Sbjct: 188 GTGGTITGIAETIKPRRPQFQAIAVEPSNSPVLSGGQPGPHKIQGIGAGFIPAIFRPELI 247 Query: 238 DEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGE 297 DE+I V + +A ARRLAR+EGLL GIS+GAA AA+QV +RPEN KLIV++ P FGE Sbjct: 248 DEVIIVDDTEAFAYARRLARQEGLLSGISAGAALWAAIQVGKRPENEDKLIVMIQPSFGE 307 Query: 298 RYLSTPLFADVAD 310 RYLST LF D+ D Sbjct: 308 RYLSTALFKDLED 320 >5XA2-A nrPDB Length = 309 Score = 358 bits (920), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 194/309 (62%), Positives = 242/309 (78%), Gaps = 2/309 (0%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 M I +D ++ IGRTPLV++ R+T G + ++AK+E NPA SVK RIG AM+ AEQ+G Sbjct: 1 MPIFKDNSESIGRTPLVQINRLTAGLSSRVLAKIEGRNPAYSVKCRIGAAMIWDAEQSGK 60 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 +KP ++EPTSGNTGIALA VCAARGY+ LTMPETMS+ERRM+L+++GA+L+LTPGAD Sbjct: 61 LKPGMHVVEPTSGNTGIALAFVCAARGYKLTLTMPETMSIERRMMLKSFGADLVLTPGAD 120 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM GAI+KAEELA +F+PQQF+NPANPAIH TT E+W DT+G+VD+ VAGVGTG Sbjct: 121 GMKGAISKAEELA-AQPGWFIPQQFKNPANPAIHVKTTGPEIWNDTEGQVDVFVAGVGTG 179 Query: 181 GTITGVAQVIK-ERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDE 239 GTITGVA+ +K E+K VAVEPAASPVL+GG G H IQGIGAGFVP D+ +VDE Sbjct: 180 GTITGVARFLKHEKKHPVHVVAVEPAASPVLAGGPAGRHKIQGIGAGFVPDTFDRSVVDE 239 Query: 240 IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERY 299 I++V +++A+ AR+LA EEG+ GIS GAA AL+VA RPE AGK IV VLPD GERY Sbjct: 240 ILSVTDDEAIETARKLAMEEGISCGISCGAAMAGALKVAARPEFAGKTIVTVLPDAGERY 299 Query: 300 LSTPLFADV 308 LST LF ++ Sbjct: 300 LSTALFENL 308 >4AEC-A nrPDB Length = 430 Score = 356 bits (914), Expect = 6e-99, Method: Compositional matrix adjust. Identities = 183/311 (58%), Positives = 239/311 (76%), Gaps = 1/311 (0%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 ++IA++++QLIG+TP+V L + G VA+I AKLE P SVKDRIG +M+ AEQ G Sbjct: 111 LNIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGF 170 Query: 61 IKP-DTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA 119 I P ++++EPTSGNTGI LA + A+RGYR +LTMP +MS+ERR+LL+A+GAEL+LT A Sbjct: 171 ISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPA 230 Query: 120 DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGT 179 GM+GA+ KAEE+ K ++ QQF+NPANP IH TT E+W DT GKVDI VAG+GT Sbjct: 231 KGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGT 290 Query: 180 GGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDE 239 GGTITGV + IKE+ P + + VEP S +LSGG+ GPH IQGIGAGF+P LDQ ++DE Sbjct: 291 GGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDE 350 Query: 240 IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERY 299 +I + +E+A+ A++LA +EGL+VGISSGAA AA++VA+RPENAGKLI VV P FGERY Sbjct: 351 VIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERY 410 Query: 300 LSTPLFADVAD 310 LSTPLF + + Sbjct: 411 LSTPLFQSIRE 421 >2ISQ-A nrPDB Length = 320 Score = 335 bits (859), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 177/305 (58%), Positives = 233/305 (76%), Gaps = 3/305 (0%) Query: 3 IAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 62 IA+D+T+LIG TPLV L V +G V + AKLE P +SVKDRIG +M+ AE+ GLIK Sbjct: 3 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 62 Query: 63 P-DTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG 121 P +++++EPTSGNTG+ LA AA+GY+ ++TMP +MS ERR++L A+G EL+LT A G Sbjct: 63 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 122 Query: 122 MSGAIAKAEE-LAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 M GAIAKAEE LAKT Y + QQFENPANP IH TT E+W+ T GK+D V+G+GTG Sbjct: 123 MKGAIAKAEEILAKTPNGYML-QQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTG 181 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GTITG + +KE+ + + VEP S +LSGG+ GPH IQGIGAGF+P VL+ DL+DE+ Sbjct: 182 GTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEV 241 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 + V +++++++AR+LA +EGLLVGISSGAA AA+++A+RPENAGKL V + P FGERYL Sbjct: 242 VQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYL 301 Query: 301 STPLF 305 ST LF Sbjct: 302 STVLF 306 >2EGU-A nrPDB Length = 308 Score = 320 bits (820), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 186/299 (62%), Positives = 228/299 (76%), Gaps = 2/299 (0%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 IT+LIG TP V+L R+ D AD+ KLEF NP +SVKDRI +AM++AAE+AG +KP Sbjct: 8 ITELIGDTPAVKLNRIVDEDSADVYLKLEFMNPGSSVKDRIALAMIEAAEKAGKLKPGDT 67 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAI 126 I+EPTSGNTGI LAMV AA+GY+ VL MP+TMSLERR LLRAYGAEL+LTPGA GM GAI Sbjct: 68 IVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAELVLTPGAQGMRGAI 127 Query: 127 AKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGV 186 AKAEEL + + YF+PQQF+N ANP IHR+TT +E+ ++D VAGVGTGGTITG Sbjct: 128 AKAEELVR-EHGYFMPQQFKNEANPEIHRLTTGKEIVEQMGDQLDAFVAGVGTGGTITGA 186 Query: 187 AQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGNE 246 +V++E P+ + AVEPA SPVLSGG+ GPH IQGIGAGFVP +LD + D +ITV E Sbjct: 187 GKVLREAYPNIKIYAVEPADSPVLSGGKPGPHKIQGIGAGFVPDILDTSIYDGVITVTTE 246 Query: 247 DALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPLF 305 +A ARR AREEG+L GISSGAA AAL+VA+ GK ++ ++P GERYLSTPL+ Sbjct: 247 EAFAAARRAAREEGILGGISSGAAIHAALKVAKE-LGKGKKVLAIIPSNGERYLSTPLY 304 >3VBE-A nrPDB Length = 344 Score = 313 bits (803), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 162/308 (52%), Positives = 218/308 (70%), Gaps = 1/308 (0%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLI 61 +I + ++QLIGRTPLV L +VT+G A + K E P S+KDR AM+ AE+ LI Sbjct: 24 NIKKHVSQLIGRTPLVYLNKVTEGCGAYVAVKQEMMQPTASIKDRPAYAMITDAEEKNLI 83 Query: 62 KP-DTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 P T ++EPTSGN GI++A + A +GY+ VLTMP SLERR+ +RA+GAELILT A Sbjct: 84 TPGKTTLIEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDPAK 143 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM G + KA EL + + QQF NPAN +H TT E+W DT+G+VDI V G+G+G Sbjct: 144 GMGGTVKKAYELLENTPNAHMLQQFSNPANTQVHFETTGPEIWEDTNGQVDIFVMGIGSG 203 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GT++GV Q +K + P+ + VEP+ S VL+GG+ GPH I G G GF P +LD D+++++ Sbjct: 204 GTVSGVGQYLKSKNPNVKIYGVEPSESNVLNGGKPGPHHITGNGVGFKPDILDLDVMEKV 263 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 + V +EDA+N+AR LA +EGL+VGISSGA TVAAL++A+ PEN GKLIV V P FGERYL Sbjct: 264 LEVSSEDAVNMARVLALKEGLMVGISSGANTVAALRLAQLPENKGKLIVTVHPSFGERYL 323 Query: 301 STPLFADV 308 S+ LF ++ Sbjct: 324 SSVLFQEL 331 >5J5V-A nrPDB Length = 323 Score = 309 bits (791), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 179/315 (56%), Positives = 221/315 (70%), Gaps = 12/315 (3%) Query: 3 IAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 62 I ED + IG TPLVRL R+ +G I+AK+E NP+ SVK RIG M+ AE+ G++K Sbjct: 4 IFEDNSLTIGHTPLVRLNRIGNG---RILAKVESRNPSFSVKCRIGANMIWDAEKRGVLK 60 Query: 63 PDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGM 122 P ++EPTSGNTGIALA V AARGY+ LTMPETMS+ERR LL+A GA L+LT GA GM Sbjct: 61 PGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAKGM 120 Query: 123 SGAIAKAEEL-AKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGG 181 GAI KAEE+ A ++Y + QQF NPANP IH TT E+W DTDG+VD+ +AGVGTGG Sbjct: 121 KGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVFIAGVGTGG 180 Query: 182 TITGVAQVIKERKPSARF--VAVEPAASPVLSGG------QKGPHPIQGIGAGFVPPVLD 233 T+TGV++ IK K VAVEP SPV++ + GPH IQGIGAGF+P LD Sbjct: 181 TLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGEEIKPGPHKIQGIGAGFIPANLD 240 Query: 234 QDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLP 293 LVD++I + NE+A++ ARRL EEG+L GISSGAA AAL++ K IVV+LP Sbjct: 241 LKLVDKVIGITNEEAISTARRLMEEEGILAGISSGAAVAAALKLQEDESFTNKNIVVILP 300 Query: 294 DFGERYLSTPLFADV 308 GERYLST LFAD+ Sbjct: 301 SSGERYLSTALFADL 315 >2PQM-A nrPDB Length = 343 Score = 293 bits (751), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 156/308 (50%), Positives = 209/308 (67%), Gaps = 6/308 (1%) Query: 3 IAEDITQLIGRTPLVRLRRVTDG----AVADIVAKLEFFNPANSVKDRIGVAMLQAAEQA 58 I +I + IG TPLV L VT+ I+ KLE+FNP +SVKDR+G ++ A + Sbjct: 13 IYHNILETIGGTPLVELHGVTEHPRIKKGTRILVKLEYFNPMSSVKDRVGFNIVYQAIKD 72 Query: 59 GLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPG 118 G +KP I+E TSGNTGIAL A GYR + MP TMS+ER+M+++A+GAELILT G Sbjct: 73 GRLKPGMEIIESTSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFGAELILTEG 132 Query: 119 ADGMSGAIAKAEELAKTD-QRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 GM GAI + ++ K + +YFV QF NP N A H T A E+W DTDG+VDIVV+ V Sbjct: 133 KKGMPGAIEEVNKMIKENPGKYFVANQFGNPDNTAAHHYT-ANEIWEDTDGEVDIVVSAV 191 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLV 237 GT GT+ GVA+ +KE+K + +AVEP S VL G KGPH IQGIGAGF+P + ++ V Sbjct: 192 GTSGTVIGVAEKLKEKKKGIKIIAVEPEESAVLEGKAKGPHGIQGIGAGFIPDIYKKEFV 251 Query: 238 DEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGE 297 DEII + +DA +AR + + +G++ G+SSGAA +A L+ A +PEN GK IV+++P GE Sbjct: 252 DEIIPIKTQDAWKMARAVVKYDGIMCGMSSGAAILAGLKEAEKPENEGKTIVIIVPSCGE 311 Query: 298 RYLSTPLF 305 RYLST L+ Sbjct: 312 RYLSTDLY 319 >3T4P-A nrPDB Length = 334 Score = 290 bits (741), Expect = 7e-79, Method: Compositional matrix adjust. Identities = 159/310 (51%), Positives = 212/310 (68%), Gaps = 2/310 (0%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAG-L 60 ++A+ I QLIG+TP + L ++ + A +V K+E NP SVKDR+G A+ AE+ G L Sbjct: 10 NVAQSIDQLIGQTPALYLNKLNNTK-AKVVLKMECENPMASVKDRLGFAIYDKAEKEGKL 68 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 I +I++E +SGNTG++LA + A RGY+ ++TMPE+MSLERR LLR +GAE+ILTP A Sbjct: 69 IPGKSIVVESSSGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLLRIFGAEVILTPAAL 128 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM GA+A A+++ + + QF N IH TT E+W T+ VD +AGVGTG Sbjct: 129 GMKGAVAMAKKIVAANPNAVLADQFATKYNALIHEETTGPEIWEQTNHNVDCFIAGVGTG 188 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GT+TGVA+ +K+ AR VAVEP SPVLSGG+ GPH IQGIG GFVP VLD+ L+DE+ Sbjct: 189 GTLTGVARALKKMGSHARIVAVEPTESPVLSGGKPGPHKIQGIGPGFVPDVLDRSLIDEV 248 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 + V +DA+ A +L R +G+ G S GA AAL++A RPE GK IV V+P FGERYL Sbjct: 249 LCVAGDDAIETALKLTRSDGVFCGFSGGANVYAALKIAERPEMEGKTIVTVIPSFGERYL 308 Query: 301 STPLFADVAD 310 ST L+ V D Sbjct: 309 STTLYRSVRD 318 >3FCA-A nrPDB Length = 291 Score = 284 bits (727), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 159/296 (53%), Positives = 207/296 (69%), Gaps = 9/296 (3%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 + +LIG TP+VRL D + I KLE NP SVKDR + M+ AE+ GL+K Sbjct: 2 MERLIGSTPIVRL----DSIDSRIALKLEKNNPGGSVKDRPALFMILDAEKRGLLKNG-- 55 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAI 126 I+EPTSGN GIA+AM+ A RG+R +LTMPETMS+ERR +L+ GAEL+LTPG GM GA+ Sbjct: 56 IVEPTSGNMGIAIAMIGAKRGHRVILTMPETMSVERRKVLKMLGAELVLTPGELGMKGAV 115 Query: 127 AKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGV 186 KA E+++ + + QFENP N H+ TT E+ + D ++D VAGVGTGGTI+GV Sbjct: 116 EKALEISRETGAHML-NQFENPYNVYSHQFTTGPEILKQMDYQIDAFVAGVGTGGTISGV 174 Query: 187 AQVIKERKPSA-RFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGN 245 +V+K + + VAVEPA SPVLSGGQ G H IQGIGAGFVP +LD+ ++DE+ITV + Sbjct: 175 GRVLKGFFGNGVKIVAVEPAKSPVLSGGQPGKHAIQGIGAGFVPKILDRSVIDEVITVED 234 Query: 246 EDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLS 301 E+A +AR LA++EGLLVGISSGA AAL+VA++ + +V V PD ERYLS Sbjct: 235 EEAYEMARYLAKKEGLLVGISSGANVAAALKVAQKLGPDAR-VVTVAPDHAERYLS 289 >5XCN-X nrPDB Length = 350 Score = 278 bits (710), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 176/316 (55%), Positives = 218/316 (68%), Gaps = 10/316 (3%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 M+I D + IG TPLVRL+ G ++V K+E NP+ SVK RIG M+ AE+ G Sbjct: 35 MAIYADNSYSIGNTPLVRLKHF--GHNGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDGT 92 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 + I++ TSGNTGIALA V AARGY+ LTMPETMSLER+ LL G L+LT GA Sbjct: 93 LTKGKEIVDATSGNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEGAK 152 Query: 121 GMSGAIAKAEELAKTD-QRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGT 179 G GAIAKAEE+ +D RY + +QFENPANP IHR TT E+W+DTDGKVD+VVAGVGT Sbjct: 153 GAKGAIAKAEEIVASDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAGVGT 212 Query: 180 GGTITGVAQVIK-ERKPSARFVAVEPAASPVLS---GGQK---GPHPIQGIGAGFVPPVL 232 GG+ITG+++ IK + VAVEP SPV+S G++ GPH IQGIGAGF+P L Sbjct: 213 GGSITGISRAIKLDFGKQITSVAVEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNL 272 Query: 233 DQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVL 292 D ++D + TV ++ AL ARRL EEG+L GISSGAA AA ++A+ PE A KLIVV+L Sbjct: 273 DLSIIDRVETVDSDTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVIL 332 Query: 293 PDFGERYLSTPLFADV 308 P ERYLST LF + Sbjct: 333 PSASERYLSTALFEGI 348 >5XEM-A nrPDB Length = 310 Score = 274 bits (701), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 145/303 (47%), Positives = 200/303 (66%), Gaps = 3/303 (0%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLI 61 S+A + LIG TPLV++ + D +I KLE NP S KDRI + M++ AE+ GLI Sbjct: 5 SLANSVIDLIGNTPLVKINNI-DTFGNEIYVKLEGSNPGRSTKDRIALKMIEEAEKEGLI 63 Query: 62 KPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG 121 DT+I+E TSGNTGI LAM+CA + Y+ + MP+TMS+ER L+RAYG E+ILT G+ G Sbjct: 64 DKDTVIIEATSGNTGIGLAMICAVKNYKLKIVMPDTMSIERIQLMRAYGTEVILTDGSLG 123 Query: 122 MSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGG 181 M + K EEL K +++YFVP QF N NP H TTAEE+ +D + KVD+ + G GTGG Sbjct: 124 MKACLEKLEELKKNEKKYFVPNQFTNVNNPKAHYETTAEEILKDLNNKVDVFICGTGTGG 183 Query: 182 TITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGA--GFVPPVLDQDLVDE 239 + +G A+ +KE+ P+ + VEPA+SP+LS G GPH IQG+G G +P V D L D+ Sbjct: 184 SFSGTAKKLKEKLPNIKTFPVEPASSPLLSKGYIGPHKIQGMGMSIGGIPAVYDGSLADD 243 Query: 240 IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERY 299 I+ ++DA + R L+ +EG+L GIS+GA AAL ++ + G IVV+ D GE+Y Sbjct: 244 ILVCEDDDAFEMMRELSFKEGILGGISTGATFKAALDYSKENADKGLKIVVLSTDSGEKY 303 Query: 300 LST 302 LS Sbjct: 304 LSN 306 >2EFY-A nrPDB Length = 304 Score = 259 bits (663), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 152/299 (50%), Positives = 203/299 (67%), Gaps = 4/299 (1%) Query: 11 IGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDT--IIL 68 IG+TP+VRL +V + +A++ KLE NP S+KDR M++ AE+ G+++P + +I+ Sbjct: 7 IGKTPVVRLAKVVEPDMAEVWVKLEGLNPGGSIKDRPAWYMIKDAEERGILRPGSGQVIV 66 Query: 69 EPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAK 128 EPTSGNTGI LAM+ A+RGYR +LTMP MS ER+ +L+A+GAEL+LT M A + Sbjct: 67 EPTSGNTGIGLAMIAASRGYRLILTMPAQMSEERKRVLKAFGAELVLTDPERRMLAAREE 126 Query: 129 AEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQ 188 A L K + F+P QF+NPAN H TT E++ +G++D V G GTGGTITGV + Sbjct: 127 ALRL-KEELGAFMPDQFKNPANVRAHYETTGPELYEALEGRIDAFVYGSGTGGTITGVGR 185 Query: 189 VIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGNEDA 248 +KER P + +AVEPA S VLSGG+ G H QG+G GF+P LD L+D +I V EDA Sbjct: 186 YLKERIPHVKVIAVEPARSNVLSGGKMGQHGFQGMGPGFIPENLDLSLLDGVIQVWEEDA 245 Query: 249 LNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPLFAD 307 +ARRLAREEGL +G+SSG AALQVAR GK + + PD G +YLSTPL+A+ Sbjct: 246 FPLARRLAREEGLFLGMSSGGIVWAALQVARE-LGPGKRVACISPDGGWKYLSTPLYAE 303 >3X43-A nrPDB Length = 332 Score = 247 bits (630), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 148/307 (48%), Positives = 203/307 (66%), Gaps = 6/307 (1%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 M + I IGRTP+VRL+R+ + + K+E FNP SVKDR+ ++++ AE GL Sbjct: 1 MPLFNSILDTIGRTPIVRLQRMAPEHTS-VYVKVESFNPGGSVKDRLALSVVLDAEAKGL 59 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 +KP I+E TSGN GIALAMV AARGYR V M +T S+ERR L+RAYG +L+L PG Sbjct: 60 LKPGDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLVLFPGHL 119 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGK-VDIVVAGVGT 179 G G A+ELA+ +F +QF+NPANP+ HR TTA E+ D GK +D V G GT Sbjct: 120 GSKGGNLIADELAEK-YGWFRARQFDNPANPSYHRETTASEILADFAGKRLDHFVTGFGT 178 Query: 180 GGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDE 239 GT+TGV Q+++ +P R VA+EP+ + +L+ G+ PH IQG+ FVP VLD+ ++D+ Sbjct: 179 TGTLTGVGQMLRVARPEVRVVALEPSNAAMLARGEWSPHQIQGLAPNFVPGVLDRSVIDD 238 Query: 240 IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARR-PENAGKLIVVVLPDFGER 298 ++T+ A + +RRLA EEG+ GIS+GA AL +A PE G +++ +LPD GER Sbjct: 239 LVTMDEVTARDTSRRLAAEEGIFAGISAGATVATALSIAEHAPE--GTVLLAMLPDTGER 296 Query: 299 YLSTPLF 305 YLST LF Sbjct: 297 YLSTFLF 303 >5XW3-A nrPDB Length = 315 Score = 243 bits (620), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 128/305 (41%), Positives = 184/305 (60%), Gaps = 2/305 (0%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 M++ + +LIG TP+V + R + + AKLEF+NP SVKDR+G +++ A + GL Sbjct: 1 MNVYRGVHELIGHTPIVEITRFSLPEGVRLFAKLEFYNPGGSVKDRLGRELIEDALEKGL 60 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 + I+EPT+GNTGI LA+ R ++ +PE S+E++ L++A GA ++ TP Sbjct: 61 VTEGGTIIEPTAGNTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATVVHTPTEQ 120 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM+GAIAKA+EL + P QF N ANP + T E+W +G+++I VAG GTG Sbjct: 121 GMTGAIAKAKELVNEIPNSYSPSQFANEANPRAYFKTLGPELWSALNGEINIFVAGAGTG 180 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GT G A +KE+ + V VEP S +L+GG+ G H +GIG F+PP L DEI Sbjct: 181 GTFMGTASYLKEKNIDIKTVIVEPEGS-ILNGGKAGSHETEGIGLEFIPPFLKTSYFDEI 239 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 T+ + +A + LA++EGLLVG SSGAA A+L A + G IV + PD ERYL Sbjct: 240 HTISDRNAFLRVKELAQKEGLLVGSSSGAAFHASLLEAEKAA-PGTNIVTIFPDSSERYL 298 Query: 301 STPLF 305 S ++ Sbjct: 299 SKDIY 303 >6AHI-A nrPDB Length = 314 Score = 243 bits (620), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 131/309 (42%), Positives = 193/309 (62%), Gaps = 8/309 (2%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAV---ADIVAKLEFFNPANSVKDRIGVAMLQAAEQ 57 M I + IGRTP+ + D + + I AKLE NP SVKDR+G ++ + Sbjct: 1 MMIITTMQDAIGRTPVFKFTN-KDYPIPLNSAIYAKLEHLNPGGSVKDRLGQYLIGEGFK 59 Query: 58 AGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTP 117 G I T I+EPT+GNTGIALA+V + + +PE S E++ ++RA GA +I TP Sbjct: 60 TGKITSKTTIIEPTAGNTGIALALVAIKHHLKTIFVVPEKFSTEKQQIMRALGALVINTP 119 Query: 118 GADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 ++G+SGAI K++ELA++ ++P QFENP NPA + T A E+ ++ + VAG+ Sbjct: 120 TSEGISGAIKKSKELAESIPDSYLPLQFENPDNPAAYYHTLAPEIVQELGTNLTSFVAGI 179 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLV 237 G+GGT G A+ +KER P+ R + VEP S +L+GG+ GPH I+GIG F+PP + + Sbjct: 180 GSGGTFAGTARYLKERIPAIRLIGVEPEGS-ILNGGEPGPHEIEGIGVEFIPPFFENLDI 238 Query: 238 DEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARR-PENAGKLIVVVLPDFG 296 D T+ +E+ + R+LA++ GLLVG SSGAA VAAL+ A+R PE G ++ + PD Sbjct: 239 DGFETISDEEGFSYTRKLAKKNGLLVGSSSGAAFVAALKEAQRLPE--GSQVLTIFPDVA 296 Query: 297 ERYLSTPLF 305 +RYLS ++ Sbjct: 297 DRYLSKGIY 305 >2JC3-A nrPDB Length = 303 Score = 235 bits (599), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 128/301 (42%), Positives = 183/301 (60%), Gaps = 10/301 (3%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 + Q IG TPLV+L+R+ ++I KLE NPA SVKDR ++M+ AE+ G IKP + Sbjct: 4 LEQTIGNTPLVKLQRIGPDNGSEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDV 63 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAI 126 ++E TSGNTGIALAM+ A +GYR L MP+ MS ERR +RAYGAELIL GM GA Sbjct: 64 LIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGAR 123 Query: 127 AKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGV 186 A +++ + + QF NP NP H TT E+WR T G++ V+ +GT GTITGV Sbjct: 124 DLALAMSERGEGKLL-DQFNNPDNPYAHYTTTGPEIWRQTSGRITHFVSSMGTTGTITGV 182 Query: 187 AQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGNE 246 ++ ++E++ V ++P + G ++ P A ++P + + LVDE++ + Sbjct: 183 SRFLREQEKPVTIVGLQPEEGSSIPGIRRWP-------AEYMPGIFNASLVDEVLDIHQN 235 Query: 247 DALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPLFA 306 DA N R LA EG+ G+SSG A AL+VAR G ++V ++ D G+RYLST +F Sbjct: 236 DAENTMRELAVREGIFCGVSSGGAVAGALRVAR--ATPGAIVVAIICDRGDRYLSTGVFG 293 Query: 307 D 307 + Sbjct: 294 E 294 >4OFX-A nrPDB Length = 319 Score = 233 bits (595), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 137/310 (44%), Positives = 197/310 (63%), Gaps = 6/310 (1%) Query: 3 IAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 62 + ++I Q+IG+TP+VRL R+ ++ K EF NP SVKDRIG AM+++AE+ G IK Sbjct: 5 VLDNILQVIGKTPVVRLHRIGQSLPCELYGKCEFLNPGGSVKDRIGAAMIESAEKQGKIK 64 Query: 63 PDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTP---GA 119 P ++EPTSGNTGI +A+ A +GYR ++TMPE MS E++++L A GA + TP Sbjct: 65 PGDTLIEPTSGNTGIGIALAGAVKGYRVIITMPEKMSHEKQVVLEALGATIYRTPTEAAY 124 Query: 120 DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGT 179 D I+ A+ L + ++ Q+ N NP IH TT +E+ D + +VV GVGT Sbjct: 125 DDPESHISLAKRLNQEIPNSYILDQYSNAENPDIHYQTTGQEILDDMGENLSMVVMGVGT 184 Query: 180 GGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDE 239 GGTI GVA+ +KE PS + + V+P S + G + P+ ++GIG F+P VLD +L+DE Sbjct: 185 GGTIIGVAKKLKEVNPSIQIIGVDPIGSILGGGDEIKPYLVEGIGYDFIPEVLDNNLIDE 244 Query: 240 IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERY 299 I + ++D+ +ARRL REEGLLVG SSG+A AA Q A+R + G+ +V+LPD Y Sbjct: 245 YIKINDKDSFLMARRLIREEGLLVGGSSGSAVWAACQAAQRLKE-GERCLVILPDAIRNY 303 Query: 300 LSTPLFADVA 309 L+ F D A Sbjct: 304 LTK--FVDDA 311 >1M54-A nrPDB Length = 363 Score = 233 bits (594), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 128/313 (40%), Positives = 189/313 (60%), Gaps = 11/313 (3%) Query: 2 SIAEDITQLIGRTPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAG 59 I DI + IG TP+VR+ ++ G +++AK EFFN SVKDRI + M++ AE+ G Sbjct: 32 KILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDG 91 Query: 60 LIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA 119 +KP I+EPTSGNTGI LA+ A RGYRC++ MPE MS E+ +LRA GAE++ TP Sbjct: 92 TLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN 151 Query: 120 ---DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAG 176 D + A L + Q+ N +NP H TTA+E+ + DGK+D++VA Sbjct: 152 ARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVAS 211 Query: 177 VGTGGTITGVAQVIKERKPSARFVAVEPAASPV-----LSGGQKGPHPIQGIGAGFVPPV 231 VGTGGTITG+A+ +KE+ P R + V+P S + L+ ++ + ++GIG F+P V Sbjct: 212 VGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTV 271 Query: 232 LDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVV 291 LD+ +VD+ +E+A AR L +EGLL G S+G+ A++ A+ + G+ VV+ Sbjct: 272 LDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQE-GQRCVVI 330 Query: 292 LPDFGERYLSTPL 304 LPD Y++ L Sbjct: 331 LPDSVRNYMTKFL 343 >4COO-A nrPDB Length = 563 Score = 233 bits (593), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 128/312 (41%), Positives = 189/312 (60%), Gaps = 11/312 (3%) Query: 3 IAEDITQLIGRTPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 I DI + IG TP+VR+ ++ G +++AK EFFN SVKDRI + M++ AE+ G Sbjct: 98 ILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGT 157 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA- 119 +KP I+EPTSGNTGI LA+ A RGYRC++ MPE MS E+ +LRA GAE++ TP Sbjct: 158 LKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNA 217 Query: 120 --DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 D + A L + Q+ N +NP H TTA+E+ + DGK+D++VA V Sbjct: 218 RFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASV 277 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPV-----LSGGQKGPHPIQGIGAGFVPPVL 232 GTGGTITG+A+ +KE+ P R + V+P S + L+ ++ + ++GIG F+P VL Sbjct: 278 GTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVL 337 Query: 233 DQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVL 292 D+ +VD+ +E+A AR L +EGLL G S+G+ A++ A+ + G+ VV+L Sbjct: 338 DRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQE-GQRCVVIL 396 Query: 293 PDFGERYLSTPL 304 PD Y++ L Sbjct: 397 PDSVRNYMTKFL 408 >5MMS-A nrPDB Length = 408 Score = 232 bits (591), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 127/309 (41%), Positives = 188/309 (60%), Gaps = 11/309 (3%) Query: 3 IAEDITQLIGRTPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 I DI + IG TP+VR+ ++ G +++AK EFFN SVKDRI + M++ AE+ G Sbjct: 76 ILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGT 135 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA- 119 +KP I+EPTSGNTGI LA+ A RGYRC++ MPE MS E+ +LRA GAE++ TP Sbjct: 136 LKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNA 195 Query: 120 --DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 D + A L + Q+ N +NP H TTA+E+ + DGK+D++VA V Sbjct: 196 RFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASV 255 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPV-----LSGGQKGPHPIQGIGAGFVPPVL 232 GTGGTITG+A+ +KE+ P R + V+P S + L+ ++ + ++GIG F+P VL Sbjct: 256 GTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVL 315 Query: 233 DQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVL 292 D+ +VD+ +E+A AR L +EGLL G S+G+ A++ A+ + G+ VV+L Sbjct: 316 DRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQE-GQRCVVIL 374 Query: 293 PDFGERYLS 301 PD Y++ Sbjct: 375 PDSVRNYMT 383 >2BHS-A nrPDB Length = 303 Score = 230 bits (587), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 126/301 (41%), Positives = 181/301 (60%), Gaps = 10/301 (3%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 + Q IG TPLV+L+R+ +++ KLE NPA SVKDR ++M+ AE+ G IKP + Sbjct: 4 LEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDV 63 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAI 126 ++E TSGNTGIALAM+ A +GYR L MP+ MS ERR +RAYGAELIL GM GA Sbjct: 64 LIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGAR 123 Query: 127 AKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGV 186 A E+A + + QF NP NP H TT E+W+ T G++ V+ +GT GTITGV Sbjct: 124 DLALEMANRGEGKLL-DQFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTGTITGV 182 Query: 187 AQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGNE 246 ++ ++E+ V ++P + G ++ P ++P + + LVDE++ + Sbjct: 183 SRFMREQSKPVTIVGLQPEEGSSIPGIRRWPTE-------YLPGIFNASLVDEVLDIHQR 235 Query: 247 DALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPLFA 306 DA N R LA EG+ G+SSG A AL+VA+ N ++V ++ D G+RYLST +F Sbjct: 236 DAENTMRELAVREGIFCGVSSGGAVAGALRVAK--ANPDAVVVAIICDRGDRYLSTGVFG 293 Query: 307 D 307 + Sbjct: 294 E 294 >5B1I-A nrPDB Length = 311 Score = 224 bits (570), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 130/305 (42%), Positives = 186/305 (60%), Gaps = 5/305 (1%) Query: 5 EDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPD 64 + + +LIG TPL+ L + + I AKLE FNP S+ DR+G +++ Q G + Sbjct: 4 QHVQELIGHTPLMALP-IEVPNHSHIYAKLEMFNPGGSIADRLGAYLIEDGLQRGRVNAK 62 Query: 65 TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSG 124 T I+EPT+GNTGI LA+ A R +L +PE S+E+++L++A GAE++ TP +G+ G Sbjct: 63 TTIIEPTAGNTGIGLALATQAHHLRTILVVPEKFSMEKQVLMQALGAEIVHTPSEEGIKG 122 Query: 125 AIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTIT 184 AI KAE LA T +VP QF+NPANPA + T A E+ D + VAG G+GGT Sbjct: 123 AIRKAEALAATISNSYVPMQFKNPANPAAYYHTLAPEILADMPAPITAFVAGAGSGGTFA 182 Query: 185 GVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVG 244 GVA ++ + + + V VEP S +L+GG H +GIG F+PP DQ +D+ +T+ Sbjct: 183 GVAAYLQAQDSATKAVVVEPEGS-ILNGGPAHAHRTEGIGVEFIPPFFDQVRIDQTLTIA 241 Query: 245 NEDALNVARRLAREEGLLVGISSGAATVAALQVARR-PENAGKLIVVVLPDFGERYLSTP 303 + DA R LAR+ GLL+G SSGAA A+LQ+A P N+ IV + PD ERYLS Sbjct: 242 DNDAFAQVRHLARDHGLLIGSSSGAALAASLQLATNLPANSH--IVTIFPDSSERYLSQK 299 Query: 304 LFADV 308 ++ + Sbjct: 300 IYTKL 304 >3PC3-A nrPDB Length = 527 Score = 221 bits (564), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 134/309 (43%), Positives = 183/309 (59%), Gaps = 11/309 (3%) Query: 3 IAEDITQLIGRTPLVRLRRV--TDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 I +I ++IG TPLV+L + +DG ++ AK EF NP SVKDRIG M+Q AE+ GL Sbjct: 50 ITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGL 109 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTP--- 117 +KP I+EPTSGNTGI LAM CA +GY+C++ MPE MS E+ LR GA++I TP Sbjct: 110 LKPGYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEA 169 Query: 118 GADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 D G I A++L + V Q+ N NP H TA E+ D KVD++V Sbjct: 170 AYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSA 229 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPV-----LSGGQKGPHPIQGIGAGFVPPVL 232 GT GTI+G+ + IKE+ PS + V V+P S + L+ + ++GIG F P V Sbjct: 230 GTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPPTVF 289 Query: 233 DQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVL 292 D +VD +G+ D ++RRL EEGLL G SSG A AAL+ AR+ + G+ VV+L Sbjct: 290 DDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHARKLKK-GQRCVVIL 348 Query: 293 PDFGERYLS 301 PD Y++ Sbjct: 349 PDGIRNYMT 357 >5OHX-A nrPDB Length = 504 Score = 218 bits (555), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 138/310 (44%), Positives = 194/310 (62%), Gaps = 14/310 (4%) Query: 3 IAEDITQLIGRTPLVRLRRV--TDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 I DI IG+TPL++L + + G +I AK EF NP SVKDRI M+Q AE GL Sbjct: 35 IMPDILTAIGQTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAEDKGL 94 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 +KP I+EPTSGNTGI LAM A RGY+C++ MPE MS E+ L A GA++I TP Sbjct: 95 LKPGCTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTEA 154 Query: 121 GMSG---AIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 I+ A++L K + Q+ NP NP H TA E+W+ +GK+D +VAG Sbjct: 155 SWHSPEAHISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLVAGA 214 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPVL-----SGGQKGPHPIQGIGAGFVPPVL 232 GTGGTI+G+ + +KE P+ + +AV+P S +L S + G + ++GIG F+P VL Sbjct: 215 GTGGTISGIGRKLKELSPNIKIIAVDPKGS-ILDPSSDSQNEVGFYEVEGIGYDFIPTVL 273 Query: 233 DQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARR-PENAGKLIVVV 291 D++++D+ I + ++LN AR L R+EGLL G SSGAA +AAL++A+ PE K +V++ Sbjct: 274 DRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAALIAALKIAKDIPEE--KRMVII 331 Query: 292 LPDFGERYLS 301 LPD YL+ Sbjct: 332 LPDGIRNYLT 341 >6C2H-A nrPDB Length = 375 Score = 191 bits (485), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 117/315 (37%), Positives = 176/315 (55%), Gaps = 18/315 (5%) Query: 5 EDITQLIGRTPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 62 ++ L+G TPL+ L+++ G I AKLE +NP S+KDRI +M++ AE +G I Sbjct: 34 HNVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASGRIH 93 Query: 63 PD-TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA-- 119 P + ++EPTSGNTGI LA++ A +GYR ++T+PE MS E+ +L+A GAE+I TP A Sbjct: 94 PSRSTLIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAA 153 Query: 120 -DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTD-----GKVDIV 173 D I A++L K + Q+ N NP H T E+ R + + V Sbjct: 154 WDSPESHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAV 213 Query: 174 VAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPV-----LSGGQKGPHPIQGIGAGFV 228 VAG GTGGTI+G+++ +KE+ + V +P S + L+ + ++GIG FV Sbjct: 214 VAGAGTGGTISGISKYLKEQNDKIQIVGADPFGSILAQPENLNKTDITDYKVEGIGYDFV 273 Query: 229 PPVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVAR-RPE-NAGK 286 P VLD+ L+D ++ + AR+L EG+LVG SSG+A A ++ PE Sbjct: 274 PQVLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYCEDHPELTEDD 333 Query: 287 LIVVVLPDFGERYLS 301 +IV + PD YL+ Sbjct: 334 VIVAIFPDSIRSYLT 348 >5JJC-A nrPDB Length = 342 Score = 186 bits (472), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 120/306 (39%), Positives = 171/306 (55%), Gaps = 18/306 (5%) Query: 11 IGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEP 70 IG TPL+RL + ++ DI K EF NP SVKDR + +++ AE+ GL++P +I+E Sbjct: 9 IGNTPLIRLSKASELTGCDIYGKAEFLNPGQSVKDRAALYIIRDAEKRGLLRPGGVIVEG 68 Query: 71 TSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG--------M 122 T+GNTGI L MV A GYR + +PET S E++ LR GAELI P A + Sbjct: 69 TAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELIEVPAAPYRNPNNAVRL 128 Query: 123 SGAIAKAEELAKTDQRYFV-PQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGG 181 SG + AE+LAKT+ + QF+N N H TTA+E+WRDT ++D VA VG+GG Sbjct: 129 SGRL--AEQLAKTEPNGAIWANQFDNTVNRQAHIETTAQEIWRDTSDQIDGFVAAVGSGG 186 Query: 182 TITGVAQVIKERKPSARFVAVEP---AASPVLSGGQ---KGPHPIQGIGAGFVPPVLDQD 235 T+ G A +KER + + +P A + G+ +G +GIG G + L+ Sbjct: 187 TLAGTAIGLKERNHNIKIALADPHGAALHAFYTTGELKAEGDSITEGIGQGRITANLEGF 246 Query: 236 LVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDF 295 D + + +AL++ L EEGL +G SSG A+++A+ G IV VL D+ Sbjct: 247 TPDFSYQIPDAEALDILFALVEEEGLCLGGSSGINIAGAIRLAKDL-GPGHTIVTVLCDY 305 Query: 296 GERYLS 301 G RY S Sbjct: 306 GNRYQS 311 >5I7O-A nrPDB Length = 326 Score = 173 bits (439), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 123/319 (38%), Positives = 178/319 (55%), Gaps = 17/319 (5%) Query: 1 MSIAEDITQLIGRTPLVRLRRVT-------DGAVADIVAKLEFFNPANSVKDRIGVAMLQ 53 M+ + + Q +G TPLV L+R++ DG + AKLE NP S+KDR V M++ Sbjct: 4 MARYDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIE 63 Query: 54 AAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAEL 113 AE GL++P ILEPTSGNTGI+LAM +GYR + MPE S+ERR LL YGA++ Sbjct: 64 QAEADGLLRPGATILEPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQI 123 Query: 114 ILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIV 173 I + G + A+A A+ELA T+ + + Q+ NPAN H T E+ D ++ Sbjct: 124 IFSAAEGGSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADLP-EITHF 182 Query: 174 VAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLD 233 VAG+GT GT+ G + ++E + + VA EP +G + ++ + GFVP + D Sbjct: 183 VAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYG-------EGVYALRNMDEGFVPELYD 235 Query: 234 QDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKL--IVVV 291 +++ +VG DA+ R L EG+ GIS+GA AAL V AG+ I +V Sbjct: 236 PEILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALV 295 Query: 292 LPDFGERYLSTPLFADVAD 310 + D G +YLST +A D Sbjct: 296 VADAGWKYLSTGAYAGSLD 314 >5B55-A nrPDB Length = 340 Score = 170 bits (431), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 116/305 (38%), Positives = 175/305 (57%), Gaps = 11/305 (3%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 + L+G+TP++ L G I K E +N S+KDR+ L+ A + IK Sbjct: 13 LENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAP 72 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD-GMSGA 125 I+E TSGNTGIA + + A G+ ++ MP+ MS ER+ L+R++GA++IL + G G+ Sbjct: 73 IVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGS 132 Query: 126 IAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEV---WRDTDGKVDIVVAGVGTGGT 182 I K +E AK + ++P QF N N H E+ + + +D VAGVGTGGT Sbjct: 133 IEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGT 192 Query: 183 ITGVAQVIKERKPSARFVAVEPAASPVLSGGQK-GPHPIQGIGAGFVPPVLDQDLVDEII 241 + G+ + IKE +A+ +EP SP LS G K H I+GI F+P ++ D +D ++ Sbjct: 193 VMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISNEFIPDLVKLDKLDNVV 252 Query: 242 TVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGK--LIVVVLPDFGERY 299 +V + DA+ +A++LA+ GL VGISSGA + AL + + GK +IV V PD ++Y Sbjct: 253 SVDDGDAIVMAQKLAK-CGLGVGISSGANFIGALMLQNK---LGKDSVIVTVFPDDNKKY 308 Query: 300 LSTPL 304 LST L Sbjct: 309 LSTDL 313 >5D84-A nrPDB Length = 326 Score = 148 bits (374), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 100/295 (33%), Positives = 161/295 (54%), Gaps = 10/295 (3%) Query: 11 IGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEP 70 +G+TP+V+L ++ ++ AKLE+ NP S+KDR +++ + GLI +T ++E Sbjct: 16 VGQTPMVQLHQLF--PKHEVFAKLEYMNPGGSMKDRPAKYIIEHGIKHGLITENTHLIES 73 Query: 71 TSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGA--ELILTPGADG--MSGAI 126 TSGN GIALAM+ +G + + +S ++++YGA E++ P A G + I Sbjct: 74 TSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGANVEMVEEPDAHGGYLMTRI 133 Query: 127 AKAEE-LAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITG 185 AK +E LA D Y++ Q+ N N H E+ +D VA V T G+I G Sbjct: 134 AKVQELLATIDDAYWI-NQYANELNWQSHYHGAGTEIVETIKQPIDYFVAPVSTTGSIMG 192 Query: 186 VAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGN 245 +++ IKE P+A+ VAV+ S V+ G + + GIGA VP +L++ ++++I V + Sbjct: 193 MSRKIKEVHPNAQIVAVDAKGS-VIFGDKPINRELPGIGASRVPEILNRSEINQVIHVDD 251 Query: 246 EDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 + R+L EG+ G S+G+ A Q+ E G IV +LPD G+RYL Sbjct: 252 YQSALGCRKLIDYEGIFAGGSTGSIIAAIEQLITSIEE-GATIVTILPDRGDRYL 305 >3VSD-A nrPDB Length = 389 Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 86/292 (29%), Positives = 141/292 (48%), Gaps = 16/292 (5%) Query: 14 TPLVRLRRVTDGAVADIVAKLEFFNPAN-SVKDRIGVAMLQAAEQAGLIKPDTIILEPTS 72 TPLVR R V + KLE++NP + SV DR V ++ + ++ +++ + TS Sbjct: 97 TPLVRSRLQLPNGVR-VWLKLEWYNPFSLSVADRPAVEIISRLSRR--VEKGSLVADATS 153 Query: 73 GNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEEL 132 N G+AL+ V GYR + +P ++L R GA++I+ P A + + + Sbjct: 154 SNFGVALSAVARLYGYRARVYLPGAAEEFGKLLPRLLGAQVIVDPEAPSTVHLLPRVMKD 213 Query: 133 AKTDQRYFVPQQFENPANPAIHRVTTAEEVW-RDTDGKVDI--VVAGVGTGGTITGVAQV 189 +K + V QF N AN H TA E++ + G + + V +GT G ++ A Sbjct: 214 SKNEGFVHV-NQFYNDANFEAHMRGTAREIFVQSRRGGLALRGVAGSLGTSGHMSAAAFY 272 Query: 190 IKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGNEDAL 249 ++ PS R V V+PA + G I+ + G + + D+ + V E+A+ Sbjct: 273 LQSVDPSIRAVLVQPAQGDSIPG-------IRRVETGMLW-INMLDISYTLAEVTLEEAM 324 Query: 250 NVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLS 301 +AR +GL++G S GAA A + A + VVV+PD G +YLS Sbjct: 325 EAVVEVARSDGLVIGPSGGAAVKALAKKAAEGDLEPGDYVVVVPDTGFKYLS 376 >5X2L-A nrPDB Length = 348 Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 73/264 (27%), Positives = 115/264 (43%), Gaps = 27/264 (10%) Query: 29 DIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGY 88 ++ K E F S K R + +++ L + ++ +SGN G AL G Sbjct: 41 NLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGI 100 Query: 89 RCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAK--AEELAKTDQRYFVPQQFE 146 + +P+T +++ ++AYGA ++ +D +AK EE T+ P Q Sbjct: 101 PAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEE---TEGIMVHPNQ-- 155 Query: 147 NPANPAI--HRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEP 204 PA+ + T A EV VD +V VG GG + G+A +K KPS + A EP Sbjct: 156 ---EPAVIAGQGTIALEVLNQVP-LVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEP 211 Query: 205 A-ASPVLSGGQKGP-----HPIQGIGAGFVPPV------LDQDLVDEIITVGNEDALNVA 252 + A KG +P + I G + + +DLVD+I TV ED + A Sbjct: 212 SNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPIIRDLVDDIFTV-TEDEIKCA 270 Query: 253 RRLAREE-GLLVGISSGAATVAAL 275 +L E LL+ ++G A L Sbjct: 271 TQLVWERMKLLIEPTAGVGVAAVL 294 >3L6C-A nrPDB Length = 339 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 80/291 (27%), Positives = 129/291 (44%), Gaps = 35/291 (12%) Query: 6 DITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDT 65 +I + TP++ + A ++ K E F S K R + ++ GLI PDT Sbjct: 18 NIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIR-----GLI-PDT 71 Query: 66 I------ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA 119 + ++ +SGN G AL G + +P+T +++ ++AYGA ++ + + Sbjct: 72 LEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPS 131 Query: 120 DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAI--HRVTTAEEVWRDTDGKVDIVVAGV 177 D +A+ + +T+ P Q PA+ + T A EV VD +V V Sbjct: 132 DESRENVAQ-RIIQETEGILVHPNQ-----EPAVIAGQGTIALEVLNQVP-LVDALVVPV 184 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPA-ASPVLSGGQKGP-----HPIQGIGAGFVPPV 231 G GG + G+A IK KPS + A EP+ A KG HP + I G + Sbjct: 185 GGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSI 244 Query: 232 ------LDQDLVDEIITVGNEDALNVARRLAREE-GLLVGISSGAATVAAL 275 + +DLVD++ TV ED + A +L E LL+ ++G A L Sbjct: 245 GLNTWPIIRDLVDDVFTV-TEDEIKYATQLVWERMKLLIEPTAGVGLAAVL 294 >1TDJ-A nrPDB Length = 514 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 80/277 (28%), Positives = 130/277 (46%), Gaps = 25/277 (9%) Query: 14 TPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI--ILEPT 71 TPL ++ +++ I+ K E P +S K R AM+ AGL + ++ + Sbjct: 32 TPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMM-----AGLTEEQKAHGVITAS 86 Query: 72 SGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEE 131 +GN +A A G + ++ MP + + +R +G E++L GA+ A AKA E Sbjct: 87 AGNHAQGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLLH-GAN-FDEAKAKAIE 144 Query: 132 LAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIK 191 L++ +VP F++P A + T A E+ + D +D V VG GG GVA +IK Sbjct: 145 LSQQQGFTWVP-PFDHPMVIA-GQGTLALELLQ-QDAHLDRVFVPVGGGGLAAGVAVLIK 201 Query: 192 ERKPSARFVAVEPAASPVLSGGQKGPHPI---------QGIGA---GFVPPVLDQDLVDE 239 + P + +AVE S L HP+ +G+ G L Q+ +D+ Sbjct: 202 QLMPQIKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDD 261 Query: 240 IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQ 276 IITV + DA+ A + E+ V SGA +A ++ Sbjct: 262 IITV-DSDAICAAMKDLFEDVRAVAEPSGALALAGMK 297 >6NMX-A nrPDB Length = 354 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 77/304 (25%), Positives = 123/304 (40%), Gaps = 32/304 (10%) Query: 12 GRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPT 71 G TPL+ L ++++ ++ K E NP S KDR V + A++ G DTI+ T Sbjct: 29 GNTPLIHLPKLSEQLGIELHVKTEGVNPTGSFKDRGMVMAVAKAKEEG---NDTIMCAST 85 Query: 72 SGNTGIALAMVCAARGYRCVLTMPE-TMSLERRMLLRAYGAELILTPGADGMSGAIAKAE 130 GNT A A A +C++ +P ++ + YGAE+I G A+ Sbjct: 86 -GNTSAAAAAYAARANMKCIVIIPNGKIAFGKLAQAVMYGAEIIAIDG--NFDDALKIVR 142 Query: 131 ELAKTDQRYFVPQQFENPANPAIHRV----TTAEEVWRDTDGKVDIVVAGVGTGGTITGV 186 + + P N NP +R+ T A EV D++ VG G I+ Sbjct: 143 SICEKS-----PIALVNSVNP--YRLEGQKTAAFEVCEQLGEAPDVLAIPVGNAGNISAY 195 Query: 187 AQVIKERK-------PSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLD------ 233 + KE P R E +A+ V + + P I P D Sbjct: 196 WKGFKEYHEKNGTSLPKMRGFEAEGSAAIVRNEVIENPETIATAIRIGNPASWDKAVKAA 255 Query: 234 QDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPE-NAGKLIVVVL 292 ++ +I V +++ L+ + +AREEG+ S A+ L+ + E G +V VL Sbjct: 256 EESNGKIDEVTDDEILHAYQLIAREEGVFAEPGSCASIAGVLKQVKSGEIPKGSKVVAVL 315 Query: 293 PDFG 296 G Sbjct: 316 TGNG 319 >6HUL-B nrPDB Length = 425 Score = 43.9 bits (102), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 58/233 (24%), Positives = 96/233 (41%), Gaps = 38/233 (16%) Query: 11 IGR-TPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTII 67 IGR TPL R +R+ + A I K E P S K + A++ G+ + ++ Sbjct: 72 IGRPTPLFRAKRLEEYLKTPARIYFKYEGATPTGSHKINTAIPQAYFAKEEGI---EHVV 128 Query: 68 LEPTSGNTGIALAMVCAARGYRCVLTMPETMSLE----RRMLLRAYGAELILTP------ 117 E +G G A+A+ + + + M + +S E RR +++ YGA + +P Sbjct: 129 TETGAGQWGTAVALAASMYNMKSTIFMVK-VSYEQKPMRRSIMQLYGANVYASPTNLTEY 187 Query: 118 ------------GADGMSGAIAKAEELA-KTDQRYFVPQQFENPANPAIHRVTTAEEVWR 164 G+ G+ A+++A E A K + RY V + +H+ +E Sbjct: 188 GRKILETNPQHPGSLGI--AMSEAIEYALKNEFRYLVGSVLDVVL---LHQSVIGQETIT 242 Query: 165 DTD---GKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQ 214 D DI++ VG G G K R++AV A P S G+ Sbjct: 243 QLDLLGEDADILIGCVGGGSNFGGFTYPFIGNKKGKRYIAVSSAEIPKFSKGE 295 >5EY5-B nrPDB Length = 399 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 85/347 (24%), Positives = 148/347 (42%), Gaps = 60/347 (17%) Query: 7 ITQLIGR-TPLVRLRRVT-DGAVADIVAKLEFFNP--ANSVKDRIGVAMLQAAEQAGLIK 62 + +GR TPL +T D A I K E N A+ + + +G A+L A + Sbjct: 43 LRDYVGRPTPLYFAENLTKDLGGAKIYLKREDLNHTGAHKINNALGQALL-----AKRMG 97 Query: 63 PDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRML----LRAYGAELI-LTP 117 +I E +G G+A A V A G CV+ M +ER+ L ++ GA++ +T Sbjct: 98 KKRVIAETGAGQHGVATATVAAMFGLECVVYMG-AEDIERQALNVFRMKLLGAKVRPVTS 156 Query: 118 GADGMSGAIAKA--EELAKTDQRYFVPQQFENPA-NPAIHR---VTTAEEVWR---DTDG 168 G+ + AI +A + + + +++ P P + R EE + + +G Sbjct: 157 GSRTLKDAINEAMRDWVTNVEDTFYIIGSVVGPHPYPMMVRDFQSVIGEEARQQILEKEG 216 Query: 169 KV-DIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKG------PHPIQ 221 ++ D +VA VG G G+ + + S R + VE A + +G P + Sbjct: 217 RLPDAIVACVGGGSNAMGIFHPFIDDE-SVRLIGVEAAGKGIETGKHAATLSAGRPGVLH 275 Query: 222 G------------------IGAGFVPP-------VLDQDLVDEIITVGNEDALNVARRLA 256 G I AG P L E ++V +++AL + L+ Sbjct: 276 GAMTYLLQDEDGQIIEAHSISAGLDYPGVGPEHAYLKDTGRAEYVSVTDDEALEAFQLLS 335 Query: 257 REEGLLVGISSGAATVAALQVARRPE-NAGKLIVVVLPDFGERYLST 302 R EG++ + S A A+++A PE + ++IVV L G++ ++T Sbjct: 336 RTEGIIPALESSHAVAYAMKLA--PELSKDQIIVVNLSGRGDKDVNT 380 >3IAU-A nrPDB Length = 366 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 56/206 (27%), Positives = 89/206 (43%), Gaps = 20/206 (9%) Query: 13 RTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTS 72 +PL +++D + K E S K R M+ + L D ++ ++ Sbjct: 60 ESPLELAEKLSDRLGVNFYIKREDKQRVFSFKLRGAYNMMSNLSREEL---DKGVITASA 116 Query: 73 GN--TGIALA---MVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIA 127 GN G+ALA + C A+ + MP T + +RA G +++L A Sbjct: 117 GNHAQGVALAGQRLNCVAK-----IVMPTTTPQIKIDAVRALGGDVVLY--GKTFDEAQT 169 Query: 128 KAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVA 187 A EL++ D ++P F++P + T E+ R + V VG GG I GVA Sbjct: 170 HALELSEKDGLKYIPP-FDDPG-VIKGQGTIGTEINRQLK-DIHAVFIPVGGGGLIAGVA 226 Query: 188 QVIKERKPSARFVAVEP--AASPVLS 211 K+ P+ + + VEP AAS LS Sbjct: 227 TFFKQIAPNTKIIGVEPYGAASMTLS 252 >5OCW-B nrPDB Length = 442 Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 61/222 (27%), Positives = 92/222 (41%), Gaps = 35/222 (15%) Query: 14 TPLVRLRRVTDGA-VADIVAKLEFFNPANSVK--DRIGVAMLQAAEQAGLIKPDTIILEP 70 +PL R++ A A I K E N S K + +G A+L A + G + +I E Sbjct: 102 SPLYEATRLSQHAGSARIFLKREDLNHTGSHKINNVLGQALL--ARRMGKTR---VIAET 156 Query: 71 TSGNTGIALAMVCAARGYRCVLTMP------ETMSLERRMLLRAYGAELI-LTPGADGMS 123 +G G+A A CA G CV+ M + +++ R LL GAE++ + G+ + Sbjct: 157 GAGQHGVATATACALLGLDCVIYMGGIDTARQALNVARMRLL---GAEVVAVQTGSKTLK 213 Query: 124 GAIAKA--EELAKTDQRYFVPQQFENPANPA--------IHRVTTAE---EVWRDTDGKV 170 AI +A + +A D Y+ F A P R+ E ++ Sbjct: 214 DAINEAFRDWVANADNTYYC---FGTAAGPHPFPTMVRDFQRIIGMEARVQIQGQAGRLP 270 Query: 171 DIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSG 212 D VVA VG G G+ + P R V E A V +G Sbjct: 271 DAVVACVGGGSNAIGIFHAFLD-DPGVRLVGFEAAGDGVETG 311 >4NEG-A nrPDB Length = 400 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 11/112 (9%) Query: 7 ITQLIGR-TPLVRLRRVTDGAV-ADIVAKLEFFNP--ANSVKDRIGVAMLQAAEQAGLIK 62 + +GR TPL +T+ A I K E N A+ + + IG A+L A + Sbjct: 55 LKTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALL-----AVRMG 109 Query: 63 PDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELI 114 ++ E +G G+A A VCA G CV+ M E RR L + EL+ Sbjct: 110 KKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDV--RRQKLNVFRMELL 159 >2D1F-A nrPDB Length = 360 Score = 37.0 bits (84), Expect = 0.012, Method: Compositional matrix adjust. Identities = 73/286 (25%), Positives = 109/286 (38%), Gaps = 28/286 (9%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 +T L G TPL+ ++ I K+E NP S KDR M A A L Sbjct: 32 VTLLEGGTPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDR---GMTMAVTDA-LAHGQRA 87 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPE-TMSLERRMLLRAYGAELILTPGADGMSGA 125 +L ++GNT + A A G C + +P+ +++ + +GA++I + G Sbjct: 88 VLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQ------IDGN 141 Query: 126 IAKAEELAKTDQRYFVPQQFENPANPA-IHRVTTAEEVWRDTDGKV-DIVVAGVGTGGTI 183 ELA+ F N NP I TA D G D+ VG G I Sbjct: 142 FDDCLELARKMAADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNI 201 Query: 184 TGVAQVIKERKPSA------RFVAVEPAASPVLSGGQKGPHPIQ-------GIGAGFVPP 230 T + E R + + A + L G+ HP G A + Sbjct: 202 TAYWKGYTEYHQLGLIDKLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASWTSA 261 Query: 231 V-LDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAAL 275 V Q + +E+ L +AR EG+ V +S AA++A L Sbjct: 262 VEAQQQSKGRFLAASDEEILAAYHLVARVEGVFVEPAS-AASIAGL 306 >6AMI-A nrPDB Length = 396 Score = 36.2 bits (82), Expect = 0.018, Method: Compositional matrix adjust. Identities = 81/345 (23%), Positives = 140/345 (40%), Gaps = 67/345 (19%) Query: 14 TPLVRLRRVTD---GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEP 70 TPL +R+T+ GA + + A+ + IG A+L A + +I E Sbjct: 51 TPLYYAKRLTEKIGGAKVYLKREDLVHGGAHKTNNAIGQALL-----AKFMGKTRLIAET 105 Query: 71 TSGNTGIALAMVCAARGYRCVLTMP------ETMSLERRMLLRAYGAELI-LTPGADGMS 123 +G G+A AM A G + + M + M++ R LL GA +I + G+ + Sbjct: 106 GAGQHGVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLL---GANVIPVNSGSRTLK 162 Query: 124 GAIAKA--EELAKTDQRYFVPQQFENPA---------NPAIHRVTTAEEVWRDTDGKV-D 171 AI +A + +A + +++ P I R A+ + + +G++ D Sbjct: 163 DAINEALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQIL--EAEGQLPD 220 Query: 172 IVVAGVGTGGTITGVAQ-VIKERKPSARFVAVEPAA--------SPVLSGGQKG-PH--- 218 ++VA VG G G+ + ++K + V VE S L+ GQ G H Sbjct: 221 VIVACVGGGSNAMGIFYPFVNDKK--VKLVGVEAGGKGLESGKHSASLNAGQVGVSHGML 278 Query: 219 ------------PIQGIGAGFVPP-------VLDQDLVDEIITVGNEDALNVARRLAREE 259 P I G P L + E + V +E+AL L+R E Sbjct: 279 SYFLQDEEGQIKPSHSIAPGLDYPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSRTE 338 Query: 260 GLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPL 304 G++ + S A A+++A+ ++I+V L G++ L L Sbjct: 339 GIIPALESAHAVAYAMKLAKEMSRD-EIIIVNLSGRGDKDLDIVL 382 >5KIN-B nrPDB Length = 407 Score = 35.0 bits (79), Expect = 0.041, Method: Compositional matrix adjust. Identities = 87/360 (24%), Positives = 141/360 (39%), Gaps = 79/360 (21%) Query: 2 SIAEDITQL----IGR-TPLVRLRRVTDG-AVADIVAKLEFFNPANSVKDRIGVAMLQAA 55 S E++ QL +GR TPL + +T A I K E N + K + + A Sbjct: 43 SFQEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA 102 Query: 56 EQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELI- 114 ++ G K II E +G G+A A A C + M E +R L + EL+ Sbjct: 103 KRMGKKK---IIAETGAGQHGVATATAAALFNMECTIYMGEEDV--KRQALNVFRMELLG 157 Query: 115 -----LTPGADGMSGAIAKA--EELAKTDQRYFV------PQQFENPANPAIHRV----- 156 +T G+ + A+ A +A D +++ P F P I R Sbjct: 158 AKVEAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPF-----PEIVRDFQSVI 212 Query: 157 -TTAEEVWRDTDGKV--DIVVAGVGTGGTITGVAQVIKERKPSARF--------VAVEPA 205 A++ +RD G+ D +VA VG G G+ E + A + V E Sbjct: 213 GREAKQQYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHH 272 Query: 206 ASPVLSGGQKGPHPIQG------------------IGAGFVPPVL--DQDLVDEI----- 240 A+ + G P + G I AG P + + +I Sbjct: 273 AATLTKG---RPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASY 329 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARR--PENAGKLIVVVLPDFGER 298 + V +E+AL + L+R EG++ + S A A+++A+ PE K ++V L G++ Sbjct: 330 VPVTDEEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPE---KSMIVCLSGRGDK 386 >5YGR-A nrPDB Length = 404 Score = 34.3 bits (77), Expect = 0.072, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Query: 45 DRIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRM 104 + + A L E IK D + + T GN G +A G + V+ MP+ SL R Sbjct: 99 NSLSFAALNTPEIKEKIK-DCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAE 157 Query: 105 LLRAYGAELILT 116 +R +GAE +T Sbjct: 158 NIRHHGAECTIT 169 >5YBW-A nrPDB Length = 329 Score = 34.3 bits (77), Expect = 0.077, Method: Compositional matrix adjust. Identities = 46/204 (22%), Positives = 80/204 (39%), Gaps = 24/204 (11%) Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELI-LTPGADGMSGA 125 ++ +SGN G ALA G +C + +P+T + + YGAE++ P Sbjct: 80 VVTHSSGNHGQALAWASKRAGVKCCVVVPKTAPQVKFDAMENYGAEVVKCEPNPTSRKET 139 Query: 126 IAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITG 185 E LAK+ ++ + + + T A E+ + +D ++ V GG +G Sbjct: 140 ---CEGLAKSRGYKYISSS--DDYDVIAGQGTIALELLQQ-QPDLDAILVSVSAGGMASG 193 Query: 186 VAQVIKERKPSARFVAVEPAASPVLSGGQK----GPHP------------IQGIGAGFVP 229 + K K + VEP + K P+P +Q G P Sbjct: 194 ICVYTKNTKSDLKVFLVEPEGKMLEECISKRERLWPNPPQFLDTIADGIILQQCGNKTWP 253 Query: 230 PVLDQDLVDEIITVGNEDALNVAR 253 +L+ E+ITV N++ + R Sbjct: 254 IILELP-EKEVITVNNDNIVEAMR 276 >1VE5-A nrPDB Length = 311 Score = 33.9 bits (76), Expect = 0.082, Method: Compositional matrix adjust. Identities = 39/146 (26%), Positives = 60/146 (41%), Gaps = 17/146 (11%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 I RTPL+ R + ++ K E S K R ++ A E Sbjct: 14 IAPYTHRTPLLTSRLLDGLLGKRLLLKAEHLQKTGSFKARGALSKALALEN------PKG 67 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAI 126 +L +SGN +A G + ++ MPE S ++ RAYGAE++ G Sbjct: 68 LLAVSSGNHAQGVAYAAQVLGVKALVVMPEDASPYKKACARAYGAEVV-------DRGVT 120 Query: 127 AKA-EELAKTDQR---YFVPQQFENP 148 AK EE+A+ Q Y + F++P Sbjct: 121 AKNREEVARALQEETGYALIHPFDDP 146 >1X1Q-A nrPDB Length = 418 Score = 33.9 bits (76), Expect = 0.10, Method: Compositional matrix adjust. Identities = 83/338 (24%), Positives = 142/338 (42%), Gaps = 63/338 (18%) Query: 7 ITQLIGR-TPLVRLRRVTD-GAVADIVAKLE--FFNPANSVKDRIGVAMLQAAEQAGLIK 62 + Q GR TPL +R+++ A + K E A+ + + +G A+L A + Sbjct: 70 LRQFAGRPTPLYHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALL-----ARRMG 124 Query: 63 PDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRML----LRAYGAELI-LTP 117 +I E +G G+++A V A G CV+ M E + R+ L ++ GAE+ + Sbjct: 125 KRRVIAETGAGQHGVSVATVAALFGLECVVYMGEE-DVRRQALNVFRMKLLGAEVRPVAA 183 Query: 118 GADGMSGAIAKAEELAKTDQR--YFVPQQFENPA-NPAIHR---VTTAEEVWRDT---DG 168 G+ + A +A T+ R +++ P P + R EEV R + G Sbjct: 184 GSRTLKDATNEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLELFG 243 Query: 169 KV-DIVVAGVGTGGTITGVAQ---VIKERKPSARFVAVEPAASPVLSG--------GQKG 216 ++ D ++A VG G G+ + E +P + + VE A + +G G++G Sbjct: 244 RLPDALIAAVGGGSNAIGLFAPFAYLPEGRP--KLIGVEAAGEGLSTGRHAASIGAGKRG 301 Query: 217 -----------PH-----PIQGIGAGFVPPVLDQDL-------VDEIITVGNEDALNVAR 253 H P + AG P + + V E +V +E+AL + Sbjct: 302 VLHGSYMYLLYDHDGQITPAHSVSAGLDYPGVGPEHSYYADAGVAEYASVTDEEALEGFK 361 Query: 254 RLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVV 291 LAR EG++ + S A A +V PE +VV+ Sbjct: 362 LLARLEGIIPALESAHAIAYAAKVV--PEMDKDQVVVI 397 >5C3U-A nrPDB Length = 366 Score = 33.5 bits (75), Expect = 0.11, Method: Compositional matrix adjust. Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 8/137 (5%) Query: 5 EDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDR-IGVAMLQAAEQAGLIKP 63 +D+ L TPL+ +T ++ K+E P+ SVK R IG QA + G Sbjct: 13 DDLQSLHVATPLLHAPNLTKELECNVFLKMENIQPSGSVKMRGIGAFCYQAVQTRGT--- 69 Query: 64 DTIILEPTSG-NTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGM 122 I SG NT +A++ G ++ +P+ + +R G+ LIL + Sbjct: 70 -NIQFVCGSGPNTVLAVSYCARQLGVEAIIVVPKATNERICQSIRTDGSHLILY--GENW 126 Query: 123 SGAIAKAEELAKTDQRY 139 + A A +L + + Y Sbjct: 127 TAAEVHARKLVRRNGIY 143 >1V71-A nrPDB Length = 323 Score = 32.7 bits (73), Expect = 0.18, Method: Compositional matrix adjust. Identities = 66/297 (22%), Positives = 125/297 (42%), Gaps = 26/297 (8%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLI 61 S +E I + +TP++ V VA++ K E F + K R L A Q Sbjct: 15 SASERIKKFANKTPVLTSSTVNKEFVAEVFFKCENFQKMGAFKFR---GALNALSQLNEA 71 Query: 62 KPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG 121 + +L +SGN A+A+ G + MP + + YG ++I+ Sbjct: 72 QRKAGVLTFSSGNHAQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQVIMYDRYKD 131 Query: 122 MSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGG 181 +AK E+++ + +P +++P A + T A+E++ + G +D + +G GG Sbjct: 132 DREKMAK--EISEREGLTIIPP-YDHPHVLA-GQGTAAKELFEEV-GPLDALFVCLGGGG 186 Query: 182 TITGVAQVIKERKPSARFVAVEPAASPVLSGGQKG-----------PHPI----QGIGAG 226 ++G A + P+ VEP A + GQ+ P I Q G Sbjct: 187 LLSGSALAARHFAPNCEVYGVEPEAG---NDGQQSFRKGSIVHIDTPKTIADGAQTQHLG 243 Query: 227 FVPPVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPEN 283 + ++ VD+I+TV +E+ ++ + A ++V + + AA + + +N Sbjct: 244 NYTFSIIKEKVDDILTVSDEELIDCLKFYAARMKIVVEPTGCLSFAAARAMKEKLKN 300 >4CNG-A nrPDB Length = 255 Score = 32.3 bits (72), Expect = 0.30, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 1/42 (2%) Query: 130 EELAKTDQRYFVPQQFENPANPAIHRV-TTAEEVWRDTDGKV 170 EE+AK+D F+P E P H V E+WR+ D KV Sbjct: 140 EEIAKSDFLLFIPANPEYPVLNLSHAVGIVLYELWRNRDNKV 181 >5CVC-A nrPDB Length = 346 Score = 32.0 bits (71), Expect = 0.36, Method: Compositional matrix adjust. Identities = 42/208 (20%), Positives = 79/208 (37%), Gaps = 28/208 (13%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 I + RTP++ + + K E F A + K R + A + + K Sbjct: 30 IAPYVHRTPVMSSTSIDAMVGKKLFFKCECFQKAGAFKIRGASNSIFALDDEQVSKG--- 86 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAI 126 ++ +SGN A+A+ RG + +P + ++ YG +I + Sbjct: 87 VVTHSSGNHAAAVALAAKLRGIPAHIVIPRNAPASKVENVKCYGGHIIWSD--------- 137 Query: 127 AKAEELAKTDQRYFVPQQFENPANPA-IHRVTTAEEV---------WRDTDGKVDIVVAG 176 A + R +V ++ + IH + + + + ++D ++ Sbjct: 138 ------ASIESREYVSKRVQEETGAVLIHPINSKYTISGQGTVSLELLEQVPEIDTIIVP 191 Query: 177 VGTGGTITGVAQVIKERKPSARFVAVEP 204 + GG I+GVA K PS R +A EP Sbjct: 192 ISGGGLISGVALAAKAINPSIRILAAEP 219 >2ZSJ-A nrPDB Length = 352 Score = 31.2 bits (69), Expect = 0.56, Method: Compositional matrix adjust. Identities = 65/263 (24%), Positives = 106/263 (40%), Gaps = 33/263 (12%) Query: 7 ITQLIGRTPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPD 64 +T G TPL+ + G I K E NP S KDR + A +AG Sbjct: 24 VTLYEGNTPLIEADNLARAIGFKGKIYLKYEGLNPTGSFKDRGMTLAISKAVEAG----K 79 Query: 65 TIILEPTSGNTGIALAMVCAARGYRCVLTMPE-TMSLERRMLLRAYGAELILTPGADGMS 123 ++ ++GNT + A A G R + +P+ +++ + YGA+++ + Sbjct: 80 RAVICASTGNTSASAAAYAARAGLRAYVLLPKGAVAIGKLSQAMIYGAKVL------AIQ 133 Query: 124 GAIAKAEELAKTDQRYFVPQQFENPANPAIHRV----TTAEEVWRDTDGKV-DIVVAGVG 178 G A + + F P + N NP +R+ T A E+ DT G+ D VG Sbjct: 134 GTFDDALNIVRKIGENF-PVEIVNSVNP--YRIEGQKTAAFEI-CDTLGEAPDYHFIPVG 189 Query: 179 TGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQ-KGPHPIQGIGAGFVPPVLDQDLV 237 G IT + K + + P + G Q +G PI G+ P+ + + Sbjct: 190 NAGNITAYWKGFKIYYEEGKITKL-----PRMMGWQAEGAAPIV---KGY--PIKNPQTI 239 Query: 238 DEIITVGNEDALNVARRLAREEG 260 I +GN + A + A+E G Sbjct: 240 ATAIKIGNPYSWKSALKAAQESG 262 >3DAH-A nrPDB Length = 319 Score = 30.8 bits (68), Expect = 0.80, Method: Compositional matrix adjust. Identities = 18/37 (48%), Positives = 20/37 (54%), Gaps = 3/37 (8%) Query: 177 VGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGG 213 V T GT+ AQV+KER F A PVLSGG Sbjct: 226 VDTAGTLCKAAQVLKERGAKQVFAY---ATHPVLSGG 259 >3PZD-A nrPDB Length = 511 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 2/67 (2%) Query: 117 PGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAG 176 PG++ A+ E L KT R FVP + E A IHR V+ G I + Sbjct: 161 PGSEMEKYALFTYESLKKTKCREFVPSRDEIEA--LIHRQEMTSTVYCHGGGSCKITINS 218 Query: 177 VGTGGTI 183 T G + Sbjct: 219 HTTAGEV 225 >2GN1-A nrPDB Length = 342 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 24/254 (9%) Query: 11 IGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEP 70 I +T + R ++ +I K E S K R L + +A K ++ Sbjct: 38 IYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTEAEKRKG---VVAC 94 Query: 71 TSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAE 130 ++GN +++ CA G + MP+ + Y AE++L D + IAK Sbjct: 95 SAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLH--GDNFNDTIAKVS 152 Query: 131 ELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVI 190 E+ +T+ R F+P +++P A + T E+ D VD V+ +G GG I G+A I Sbjct: 153 EIVETEGRIFIPP-YDDPKVIA-GQGTIGLEIMEDL-YDVDNVIVPIGGGGLIAGIAIAI 209 Query: 191 KERKPSARFVAVEP------AASPVLSGGQKGPHPIQGIGAGFV----PPVLDQ----DL 236 K P+ + + V+ AAS G+ H G A P L +L Sbjct: 210 KSINPTIKVIGVQAENVHGMAAS--YYTGEITTHRTTGTLADGCDVSRPGNLTYEIVREL 267 Query: 237 VDEIITVGNEDALN 250 VD+I+ V ++ N Sbjct: 268 VDDIVLVSEDEIRN 281 >1BWR-A nrPDB Length = 233 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 15/61 (24%) Query: 157 TTAEEVWRDTDGKVD-----IVVAGVGTG----------GTITGVAQVIKERKPSARFVA 201 +T +WR +G+++ IVV VG+ G I + Q++ ER+P AR V Sbjct: 76 STQHVLWRLENGELEHIRPKIVVVWVGSNNHGHTAEQVTGGIKAIVQLVNERQPQARVVV 135 Query: 202 V 202 + Sbjct: 136 L 136 >1UIN-A nrPDB Length = 351 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 72/295 (24%), Positives = 115/295 (38%), Gaps = 36/295 (12%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADI--VAKLEFFNPANSVKDR-IGVAMLQAAEQAGLIKP 63 I+ L G TPL+ L+ + I AK E NP S KDR + +A+ +A E Sbjct: 22 ISLLEGSTPLIPLKGPEEARKKGIRLYAKYEGLNPTGSFKDRGMTLAVSKAVEGGA---- 77 Query: 64 DTIILEPTSGNTGIALAMVCAARGYRCVLTMPE-TMSLERRMLLRAYGAELILTPGADGM 122 + ++GNT + A A G ++ +P ++L + +GA ++ G Sbjct: 78 -QAVACASTGNTAASAAAYAARAGILAIVVLPAGYVALGKVAQSLVHGARIVQVEG--NF 134 Query: 123 SGAIAKAEELAKTDQRYFVPQQFENPANPAIHRV----TTAEEVWRDTDGKVDIVVAGVG 178 A+ ++L + P N NP HR+ T A EV + VG Sbjct: 135 DDALRLTQKLTEA-----FPVALVNSVNP--HRLEGQKTLAFEVVDELGDAPHYHALPVG 187 Query: 179 TGGTITG------VAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQ-------GIGA 225 G IT + + K R + + A + L G+ P G A Sbjct: 188 NAGNITAHWMGYKAYHALGKAKRLPRMLGFQAAGAAPLVLGRPVERPETLATAIRIGNPA 247 Query: 226 GFVPPVLDQDLVDEII-TVGNEDALNVARRLAREEGLLVGISSGAATVAALQVAR 279 + V ++ +I V +E+ L R LAREEG+ +S AA ++ R Sbjct: 248 SWQGAVRAKEESGGVIEAVTDEEILFAYRYLAREEGIFCEPASAAAMAGVFKLLR 302 >3R0X-A nrPDB Length = 448 Score = 28.1 bits (61), Expect = 5.3, Method: Compositional matrix adjust. Identities = 27/124 (21%), Positives = 57/124 (45%), Gaps = 24/124 (19%) Query: 40 ANSVKDRIGVA-MLQAAE----QAGLIKPD---TIILEP--------------TSGNTGI 77 + S+K R G+ +L AE +AGL+ D +++L P ++GN G+ Sbjct: 112 SGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGL 171 Query: 78 ALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEELAKTDQ 137 ++ ++ A G++ + M ++ LR++G ++ D A+ + + A++D Sbjct: 172 SIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYE--DDYGVAVEQGRKAAQSDP 229 Query: 138 RYFV 141 F Sbjct: 230 NCFF 233 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2Q3D-A nrPDB 460 e-130 4I1Y-A nrPDB 417 e-117 5XA2-A nrPDB 408 e-114 4LMA-A nrPDB 402 e-112 4AEC-A nrPDB 400 e-112 4LMB-A nrPDB 394 e-110 3VBE-A nrPDB 392 e-109 4COO-A nrPDB 384 e-107 2ISQ-A nrPDB 383 e-107 1M54-A nrPDB 381 e-106 5MMS-A nrPDB 381 e-106 5XW3-A nrPDB 369 e-103 3FCA-A nrPDB 368 e-102 3T4P-A nrPDB 367 e-102 5J5V-A nrPDB 365 e-101 2EGU-A nrPDB 363 e-101 2PQM-A nrPDB 362 e-100 2EFY-A nrPDB 360 e-100 5XEM-A nrPDB 360 e-100 2BHS-A nrPDB 359 1e-99 6AHI-A nrPDB 358 1e-99 2JC3-A nrPDB 357 4e-99 4OFX-A nrPDB 353 6e-98 5OHX-A nrPDB 353 8e-98 3PC3-A nrPDB 350 4e-97 5XCN-X nrPDB 339 1e-93 6C2H-A nrPDB 337 4e-93 3X43-A nrPDB 331 2e-91 5B1I-A nrPDB 323 6e-89 5JJC-A nrPDB 311 3e-85 5D84-A nrPDB 304 2e-83 5B55-A nrPDB 300 5e-82 5I7O-A nrPDB 298 3e-81 5X2L-A nrPDB 226 1e-59 3VSD-A nrPDB 222 2e-58 6NMX-A nrPDB 213 7e-56 5EY5-B nrPDB 211 4e-55 3L6C-A nrPDB 199 2e-51 1TDJ-A nrPDB 193 6e-50 5OCW-B nrPDB 188 3e-48 6HUL-B nrPDB 172 1e-43 3IAU-A nrPDB 172 2e-43 Sequences not found previously or not previously below threshold: 6AMI-A nrPDB 179 1e-45 5KIN-B nrPDB 173 8e-44 5KZM-B nrPDB 164 5e-41 4NEG-A nrPDB 160 8e-40 1X1Q-A nrPDB 157 5e-39 1CX9-B nrPDB 152 1e-37 2ZSJ-A nrPDB 147 5e-36 5YBW-A nrPDB 144 5e-35 2D1F-A nrPDB 143 8e-35 1V71-A nrPDB 138 2e-33 1UIN-A nrPDB 133 1e-31 2GN1-A nrPDB 128 2e-30 5CVC-A nrPDB 117 7e-27 6EQN-B nrPDB 112 2e-25 1VE5-A nrPDB 111 3e-25 1PWH-A nrPDB 103 1e-22 5C3U-A nrPDB 92 3e-19 1E5X-A nrPDB 87 9e-18 4D9F-A nrPDB 87 9e-18 5YGR-A nrPDB 84 9e-17 1J0B-A nrPDB 82 3e-16 4H27-A nrPDB 82 4e-16 1RQX-A nrPDB 80 9e-16 2RKB-A nrPDB 78 6e-15 4D9G-A nrPDB 74 6e-14 3SS9-X nrPDB 63 1e-10 3R0X-A nrPDB 60 9e-10 1J0D-A nrPDB 60 1e-09 2VCY-A nrPDB 38 0.005 1VB3-A nrPDB 38 0.007 3IP1-A nrPDB 36 0.025 4E77-A nrPDB 36 0.030 5OC1-A nrPDB 35 0.040 4EI8-A nrPDB 34 0.11 2UUU-A nrPDB 34 0.11 3AOE-E nrPDB 33 0.21 1G3N-B nrPDB 33 0.21 2UUQ-A nrPDB 32 0.31 4RVS-A nrPDB 31 0.49 1R18-A nrPDB 31 0.61 4J6F-A nrPDB 31 0.79 5Y2D-A nrPDB 31 0.82 1PL8-A nrPDB 30 1.00 5Y28-A nrPDB 30 1.0 1DEL-A nrPDB 30 1.2 1ZYK-A nrPDB 30 1.3 2Y4O-A nrPDB 30 1.3 3N0G-A nrPDB 30 1.7 5G2R-A nrPDB 30 2.0 2AN1-A nrPDB 30 2.1 3J9R-A nrPDB 29 2.2 3CJR-A nrPDB 29 2.5 4HAO-A nrPDB 29 2.6 1IHO-A nrPDB 29 3.3 3FBG-A nrPDB 29 3.5 3KIZ-A nrPDB 28 4.1 3GUZ-A nrPDB 28 4.1 2VPQ-A nrPDB 28 5.0 3GFB-A nrPDB 28 5.1 5YLN-A nrPDB 28 5.4 1GPJ-A nrPDB 28 6.0 3DM5-A nrPDB 28 6.0 1U6I-A nrPDB 28 6.5 6ETZ-A nrPDB 28 7.8 2DR1-A nrPDB 27 9.3 1E3W-A nrPDB 27 9.5 >2Q3D-A nrPDB Length = 313 Score = 460 bits (1184), Expect = e-130, Method: Composition-based stats. Identities = 310/310 (100%), Positives = 310/310 (100%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL Sbjct: 4 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 63 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD Sbjct: 64 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 123 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG Sbjct: 124 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 183 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI Sbjct: 184 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 243 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL Sbjct: 244 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 303 Query: 301 STPLFADVAD 310 STPLFADVAD Sbjct: 304 STPLFADVAD 313 >4I1Y-A nrPDB Length = 314 Score = 417 bits (1071), Expect = e-117, Method: Composition-based stats. Identities = 263/310 (84%), Positives = 290/310 (93%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 M+IAE+I QLIG TPLVRLRRVTDGA AD+VAKLE FNPA S+KDRIGVAM+ AAE+AGL Sbjct: 5 MTIAENIAQLIGGTPLVRLRRVTDGAAADVVAKLESFNPAGSIKDRIGVAMIDAAEKAGL 64 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 IKPDTIILEPTSGNTGIALAMV AARGY+CVLTMP+TMS+ERRMLLRAYGAEL+LTPGA+ Sbjct: 65 IKPDTIILEPTSGNTGIALAMVSAARGYKCVLTMPDTMSIERRMLLRAYGAELVLTPGAE 124 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM+GAIAKAEELAKTD RYF+PQQFENPANPA+H VTTAEEVWRDTDGKVDI V+GVGTG Sbjct: 125 GMAGAIAKAEELAKTDDRYFIPQQFENPANPAVHAVTTAEEVWRDTDGKVDIFVSGVGTG 184 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GTITGVAQVIK+R+PSA+FVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLD LVDE+ Sbjct: 185 GTITGVAQVIKQRRPSAQFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDLALVDEV 244 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 ITVGN+DAL +ARR+A EEGLL GISSGAA AA ++A RPENAGKLIVVVLPDFGERYL Sbjct: 245 ITVGNDDALELARRMATEEGLLFGISSGAAVWAARELAHRPENAGKLIVVVLPDFGERYL 304 Query: 301 STPLFADVAD 310 ST LFAD+++ Sbjct: 305 STVLFADLSE 314 >5XA2-A nrPDB Length = 309 Score = 408 bits (1048), Expect = e-114, Method: Composition-based stats. Identities = 194/310 (62%), Positives = 242/310 (78%), Gaps = 2/310 (0%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 M I +D ++ IGRTPLV++ R+T G + ++AK+E NPA SVK RIG AM+ AEQ+G Sbjct: 1 MPIFKDNSESIGRTPLVQINRLTAGLSSRVLAKIEGRNPAYSVKCRIGAAMIWDAEQSGK 60 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 +KP ++EPTSGNTGIALA VCAARGY+ LTMPETMS+ERRM+L+++GA+L+LTPGAD Sbjct: 61 LKPGMHVVEPTSGNTGIALAFVCAARGYKLTLTMPETMSIERRMMLKSFGADLVLTPGAD 120 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM GAI+KAEELA +F+PQQF+NPANPAIH TT E+W DT+G+VD+ VAGVGTG Sbjct: 121 GMKGAISKAEELA-AQPGWFIPQQFKNPANPAIHVKTTGPEIWNDTEGQVDVFVAGVGTG 179 Query: 181 GTITGVAQVIK-ERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDE 239 GTITGVA+ +K E+K VAVEPAASPVL+GG G H IQGIGAGFVP D+ +VDE Sbjct: 180 GTITGVARFLKHEKKHPVHVVAVEPAASPVLAGGPAGRHKIQGIGAGFVPDTFDRSVVDE 239 Query: 240 IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERY 299 I++V +++A+ AR+LA EEG+ GIS GAA AL+VA RPE AGK IV VLPD GERY Sbjct: 240 ILSVTDDEAIETARKLAMEEGISCGISCGAAMAGALKVAARPEFAGKTIVTVLPDAGERY 299 Query: 300 LSTPLFADVA 309 LST LF ++ Sbjct: 300 LSTALFENLR 309 >4LMA-A nrPDB Length = 326 Score = 402 bits (1032), Expect = e-112, Method: Composition-based stats. Identities = 199/313 (63%), Positives = 246/313 (78%), Gaps = 3/313 (0%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVA--DIVAKLEFFNPANSVKDRIGVAMLQAAEQA 58 M IA D+T+L+GRTPLV+L R+ IV KLE NPA SVKDRIG M+ +AE+A Sbjct: 8 MRIAHDVTELVGRTPLVQLNRIPQAEGCLGRIVMKLEGMNPAASVKDRIGTHMINSAEKA 67 Query: 59 GLIKPDTII-LEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTP 117 GLI P+T + +EPTSGNTGIALAM AA+GYR +LTMPETMSLERR +L+AYGA L LTP Sbjct: 68 GLINPETTVLVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELTP 127 Query: 118 GADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 G+ GM GAI +A+++ + ++ QQF NP+NP IHR+TTAEE+W+DT+G+VD +VAGV Sbjct: 128 GSQGMKGAILRAQQIVDSIPGAYMLQQFRNPSNPEIHRLTTAEEIWQDTEGQVDFIVAGV 187 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLV 237 GTGGTITGVA+VIK RKPS + VAVEP SPV+SGG GPH IQGIGAGF+P VL DL+ Sbjct: 188 GTGGTITGVAEVIKSRKPSFQVVAVEPFNSPVISGGNPGPHKIQGIGAGFIPEVLRTDLI 247 Query: 238 DEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGE 297 DE+ITV +E+A RRLA+EEGLL GISSGA AA+Q+A+RPEN GKLIVV+ P FGE Sbjct: 248 DEVITVSDEEAFQFGRRLAKEEGLLSGISSGANLCAAIQLAQRPENEGKLIVVIQPSFGE 307 Query: 298 RYLSTPLFADVAD 310 RYLST +F ++ + Sbjct: 308 RYLSTLMFQNIEE 320 >4AEC-A nrPDB Length = 430 Score = 400 bits (1027), Expect = e-112, Method: Composition-based stats. Identities = 183/311 (58%), Positives = 239/311 (76%), Gaps = 1/311 (0%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 ++IA++++QLIG+TP+V L + G VA+I AKLE P SVKDRIG +M+ AEQ G Sbjct: 111 LNIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGF 170 Query: 61 IKPD-TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA 119 I P ++++EPTSGNTGI LA + A+RGYR +LTMP +MS+ERR+LL+A+GAEL+LT A Sbjct: 171 ISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPA 230 Query: 120 DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGT 179 GM+GA+ KAEE+ K ++ QQF+NPANP IH TT E+W DT GKVDI VAG+GT Sbjct: 231 KGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGT 290 Query: 180 GGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDE 239 GGTITGV + IKE+ P + + VEP S +LSGG+ GPH IQGIGAGF+P LDQ ++DE Sbjct: 291 GGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDE 350 Query: 240 IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERY 299 +I + +E+A+ A++LA +EGL+VGISSGAA AA++VA+RPENAGKLI VV P FGERY Sbjct: 351 VIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERY 410 Query: 300 LSTPLFADVAD 310 LSTPLF + + Sbjct: 411 LSTPLFQSIRE 421 >4LMB-A nrPDB Length = 322 Score = 394 bits (1012), Expect = e-110, Method: Composition-based stats. Identities = 205/313 (65%), Positives = 244/313 (77%), Gaps = 3/313 (0%) Query: 1 MSIAEDITQLIGRTPLVRLRRV--TDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQA 58 M IA DITQL+GRTPLV+L R+ +G A IV KLE NPA SVKDRIGV+M++ AE A Sbjct: 8 MLIARDITQLVGRTPLVQLNRIPVAEGVKARIVVKLESMNPAASVKDRIGVSMVEDAEAA 67 Query: 59 GLIKPDTII-LEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTP 117 GLI PD I +EPTSGNTGIALAMV AA+GYR VLTMPETMSLERR +L+AYGA+L LTP Sbjct: 68 GLIHPDKTILVEPTSGNTGIALAMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELTP 127 Query: 118 GADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 G+ GM GAI +AEE+ + + QQF NPANP IHR TTAEE+W DTDG VDIV+ GV Sbjct: 128 GSQGMEGAITRAEEIVENTPNAYSLQQFRNPANPKIHRETTAEEIWADTDGLVDIVIGGV 187 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLV 237 GTGGTITG+A+ IK R+P + +AVEP+ SPVLSGGQ GPH IQGIGAGF+P + +L+ Sbjct: 188 GTGGTITGIAETIKPRRPQFQAIAVEPSNSPVLSGGQPGPHKIQGIGAGFIPAIFRPELI 247 Query: 238 DEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGE 297 DE+I V + +A ARRLAR+EGLL GIS+GAA AA+QV +RPEN KLIV++ P FGE Sbjct: 248 DEVIIVDDTEAFAYARRLARQEGLLSGISAGAALWAAIQVGKRPENEDKLIVMIQPSFGE 307 Query: 298 RYLSTPLFADVAD 310 RYLST LF D+ D Sbjct: 308 RYLSTALFKDLED 320 >3VBE-A nrPDB Length = 344 Score = 392 bits (1007), Expect = e-109, Method: Composition-based stats. Identities = 162/310 (52%), Positives = 218/310 (70%), Gaps = 1/310 (0%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLI 61 +I + ++QLIGRTPLV L +VT+G A + K E P S+KDR AM+ AE+ LI Sbjct: 24 NIKKHVSQLIGRTPLVYLNKVTEGCGAYVAVKQEMMQPTASIKDRPAYAMITDAEEKNLI 83 Query: 62 KPD-TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 P T ++EPTSGN GI++A + A +GY+ VLTMP SLERR+ +RA+GAELILT A Sbjct: 84 TPGKTTLIEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDPAK 143 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM G + KA EL + + QQF NPAN +H TT E+W DT+G+VDI V G+G+G Sbjct: 144 GMGGTVKKAYELLENTPNAHMLQQFSNPANTQVHFETTGPEIWEDTNGQVDIFVMGIGSG 203 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GT++GV Q +K + P+ + VEP+ S VL+GG+ GPH I G G GF P +LD D+++++ Sbjct: 204 GTVSGVGQYLKSKNPNVKIYGVEPSESNVLNGGKPGPHHITGNGVGFKPDILDLDVMEKV 263 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 + V +EDA+N+AR LA +EGL+VGISSGA TVAAL++A+ PEN GKLIV V P FGERYL Sbjct: 264 LEVSSEDAVNMARVLALKEGLMVGISSGANTVAALRLAQLPENKGKLIVTVHPSFGERYL 323 Query: 301 STPLFADVAD 310 S+ LF ++ Sbjct: 324 SSVLFQELRQ 333 >4COO-A nrPDB Length = 563 Score = 384 bits (986), Expect = e-107, Method: Composition-based stats. Identities = 128/313 (40%), Positives = 189/313 (60%), Gaps = 11/313 (3%) Query: 2 SIAEDITQLIGRTPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAG 59 I DI + IG TP+VR+ ++ G +++AK EFFN SVKDRI + M++ AE+ G Sbjct: 97 KILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDG 156 Query: 60 LIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA 119 +KP I+EPTSGNTGI LA+ A RGYRC++ MPE MS E+ +LRA GAE++ TP Sbjct: 157 TLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN 216 Query: 120 ---DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAG 176 D + A L + Q+ N +NP H TTA+E+ + DGK+D++VA Sbjct: 217 ARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVAS 276 Query: 177 VGTGGTITGVAQVIKERKPSARFVAVEPAASPV-----LSGGQKGPHPIQGIGAGFVPPV 231 VGTGGTITG+A+ +KE+ P R + V+P S + L+ ++ + ++GIG F+P V Sbjct: 277 VGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTV 336 Query: 232 LDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVV 291 LD+ +VD+ +E+A AR L +EGLL G S+G+ A++ A+ + G+ VV+ Sbjct: 337 LDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQ-EGQRCVVI 395 Query: 292 LPDFGERYLSTPL 304 LPD Y++ L Sbjct: 396 LPDSVRNYMTKFL 408 >2ISQ-A nrPDB Length = 320 Score = 383 bits (983), Expect = e-107, Method: Composition-based stats. Identities = 172/305 (56%), Positives = 229/305 (75%), Gaps = 1/305 (0%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLI 61 IA+D+T+LIG TPLV L V +G V + AKLE P +SVKDRIG +M+ AE+ GLI Sbjct: 2 RIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLI 61 Query: 62 KPD-TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 KP ++++EPTSGNTG+ LA AA+GY+ ++TMP +MS ERR++L A+G EL+LT A Sbjct: 62 KPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAK 121 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM GAIAKAEE+ ++ QQFENPANP IH TT E+W+ T GK+D V+G+GTG Sbjct: 122 GMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTG 181 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GTITG + +KE+ + + VEP S +LSGG+ GPH IQGIGAGF+P VL+ DL+DE+ Sbjct: 182 GTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEV 241 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 + V +++++++AR+LA +EGLLVGISSGAA AA+++A+RPENAGKL V + P FGERYL Sbjct: 242 VQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYL 301 Query: 301 STPLF 305 ST LF Sbjct: 302 STVLF 306 >1M54-A nrPDB Length = 363 Score = 381 bits (980), Expect = e-106, Method: Composition-based stats. Identities = 128/313 (40%), Positives = 189/313 (60%), Gaps = 11/313 (3%) Query: 2 SIAEDITQLIGRTPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAG 59 I DI + IG TP+VR+ ++ G +++AK EFFN SVKDRI + M++ AE+ G Sbjct: 32 KILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDG 91 Query: 60 LIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA 119 +KP I+EPTSGNTGI LA+ A RGYRC++ MPE MS E+ +LRA GAE++ TP Sbjct: 92 TLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN 151 Query: 120 ---DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAG 176 D + A L + Q+ N +NP H TTA+E+ + DGK+D++VA Sbjct: 152 ARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVAS 211 Query: 177 VGTGGTITGVAQVIKERKPSARFVAVEPAASPV-----LSGGQKGPHPIQGIGAGFVPPV 231 VGTGGTITG+A+ +KE+ P R + V+P S + L+ ++ + ++GIG F+P V Sbjct: 212 VGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTV 271 Query: 232 LDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVV 291 LD+ +VD+ +E+A AR L +EGLL G S+G+ A++ A+ + G+ VV+ Sbjct: 272 LDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQ-EGQRCVVI 330 Query: 292 LPDFGERYLSTPL 304 LPD Y++ L Sbjct: 331 LPDSVRNYMTKFL 343 >5MMS-A nrPDB Length = 408 Score = 381 bits (979), Expect = e-106, Method: Composition-based stats. Identities = 128/313 (40%), Positives = 189/313 (60%), Gaps = 11/313 (3%) Query: 2 SIAEDITQLIGRTPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAG 59 I DI + IG TP+VR+ ++ G +++AK EFFN SVKDRI + M++ AE+ G Sbjct: 75 KILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDG 134 Query: 60 LIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA 119 +KP I+EPTSGNTGI LA+ A RGYRC++ MPE MS E+ +LRA GAE++ TP Sbjct: 135 TLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN 194 Query: 120 ---DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAG 176 D + A L + Q+ N +NP H TTA+E+ + DGK+D++VA Sbjct: 195 ARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVAS 254 Query: 177 VGTGGTITGVAQVIKERKPSARFVAVEPAASPV-----LSGGQKGPHPIQGIGAGFVPPV 231 VGTGGTITG+A+ +KE+ P R + V+P S + L+ ++ + ++GIG F+P V Sbjct: 255 VGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTV 314 Query: 232 LDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVV 291 LD+ +VD+ +E+A AR L +EGLL G S+G+ A++ A+ + G+ VV+ Sbjct: 315 LDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQ-EGQRCVVI 373 Query: 292 LPDFGERYLSTPL 304 LPD Y++ L Sbjct: 374 LPDSVRNYMTKFL 386 >5XW3-A nrPDB Length = 315 Score = 369 bits (948), Expect = e-103, Method: Composition-based stats. Identities = 128/307 (41%), Positives = 184/307 (59%), Gaps = 2/307 (0%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 M++ + +LIG TP+V + R + + AKLEF+NP SVKDR+G +++ A + GL Sbjct: 1 MNVYRGVHELIGHTPIVEITRFSLPEGVRLFAKLEFYNPGGSVKDRLGRELIEDALEKGL 60 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 + I+EPT+GNTGI LA+ R ++ +PE S+E++ L++A GA ++ TP Sbjct: 61 VTEGGTIIEPTAGNTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATVVHTPTEQ 120 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM+GAIAKA+EL + P QF N ANP + T E+W +G+++I VAG GTG Sbjct: 121 GMTGAIAKAKELVNEIPNSYSPSQFANEANPRAYFKTLGPELWSALNGEINIFVAGAGTG 180 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GT G A +KE+ + V VEP S +L+GG+ G H +GIG F+PP L DEI Sbjct: 181 GTFMGTASYLKEKNIDIKTVIVEPEGS-ILNGGKAGSHETEGIGLEFIPPFLKTSYFDEI 239 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 T+ + +A + LA++EGLLVG SSGAA A+L A + G IV + PD ERYL Sbjct: 240 HTISDRNAFLRVKELAQKEGLLVGSSSGAAFHASLLEAEKAA-PGTNIVTIFPDSSERYL 298 Query: 301 STPLFAD 307 S ++ Sbjct: 299 SKDIYKG 305 >3FCA-A nrPDB Length = 291 Score = 368 bits (945), Expect = e-102, Method: Composition-based stats. Identities = 159/296 (53%), Positives = 205/296 (69%), Gaps = 9/296 (3%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 + +LIG TP+VRL D + I KLE NP SVKDR + M+ AE+ GL+K Sbjct: 2 MERLIGSTPIVRL----DSIDSRIALKLEKNNPGGSVKDRPALFMILDAEKRGLLKNG-- 55 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAI 126 I+EPTSGN GIA+AM+ A RG+R +LTMPETMS+ERR +L+ GAEL+LTPG GM GA+ Sbjct: 56 IVEPTSGNMGIAIAMIGAKRGHRVILTMPETMSVERRKVLKMLGAELVLTPGELGMKGAV 115 Query: 127 AKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGV 186 KA E+++ + QFENP N H+ TT E+ + D ++D VAGVGTGGTI+GV Sbjct: 116 EKALEISRETG-AHMLNQFENPYNVYSHQFTTGPEILKQMDYQIDAFVAGVGTGGTISGV 174 Query: 187 AQVIKERKPS-ARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGN 245 +V+K + + VAVEPA SPVLSGGQ G H IQGIGAGFVP +LD+ ++DE+ITV + Sbjct: 175 GRVLKGFFGNGVKIVAVEPAKSPVLSGGQPGKHAIQGIGAGFVPKILDRSVIDEVITVED 234 Query: 246 EDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLS 301 E+A +AR LA++EGLLVGISSGA AAL+VA++ +V V PD ERYLS Sbjct: 235 EEAYEMARYLAKKEGLLVGISSGANVAAALKVAQKL-GPDARVVTVAPDHAERYLS 289 >3T4P-A nrPDB Length = 334 Score = 367 bits (943), Expect = e-102, Method: Composition-based stats. Identities = 158/310 (50%), Positives = 212/310 (68%), Gaps = 2/310 (0%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLI 61 ++A+ I QLIG+TP + L ++ + A +V K+E NP SVKDR+G A+ AE+ G + Sbjct: 10 NVAQSIDQLIGQTPALYLNKLNN-TKAKVVLKMECENPMASVKDRLGFAIYDKAEKEGKL 68 Query: 62 KPD-TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 P +I++E +SGNTG++LA + A RGY+ ++TMPE+MSLERR LLR +GAE+ILTP A Sbjct: 69 IPGKSIVVESSSGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLLRIFGAEVILTPAAL 128 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 GM GA+A A+++ + + QF N IH TT E+W T+ VD +AGVGTG Sbjct: 129 GMKGAVAMAKKIVAANPNAVLADQFATKYNALIHEETTGPEIWEQTNHNVDCFIAGVGTG 188 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 GT+TGVA+ +K+ AR VAVEP SPVLSGG+ GPH IQGIG GFVP VLD+ L+DE+ Sbjct: 189 GTLTGVARALKKMGSHARIVAVEPTESPVLSGGKPGPHKIQGIGPGFVPDVLDRSLIDEV 248 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 + V +DA+ A +L R +G+ G S GA AAL++A RPE GK IV V+P FGERYL Sbjct: 249 LCVAGDDAIETALKLTRSDGVFCGFSGGANVYAALKIAERPEMEGKTIVTVIPSFGERYL 308 Query: 301 STPLFADVAD 310 ST L+ V D Sbjct: 309 STTLYRSVRD 318 >5J5V-A nrPDB Length = 323 Score = 365 bits (937), Expect = e-101, Method: Composition-based stats. Identities = 178/316 (56%), Positives = 221/316 (69%), Gaps = 12/316 (3%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLI 61 I ED + IG TPLVRL R+ +G I+AK+E NP+ SVK RIG M+ AE+ G++ Sbjct: 3 KIFEDNSLTIGHTPLVRLNRIGNG---RILAKVESRNPSFSVKCRIGANMIWDAEKRGVL 59 Query: 62 KPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG 121 KP ++EPTSGNTGIALA V AARGY+ LTMPETMS+ERR LL+A GA L+LT GA G Sbjct: 60 KPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAKG 119 Query: 122 MSGAIAKAEELAKTDQ-RYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 M GAI KAEE+ ++ +Y + QQF NPANP IH TT E+W DTDG+VD+ +AGVGTG Sbjct: 120 MKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVFIAGVGTG 179 Query: 181 GTITGVAQVIKERKPSARF--VAVEPAASPVLSGG------QKGPHPIQGIGAGFVPPVL 232 GT+TGV++ IK K VAVEP SPV++ + GPH IQGIGAGF+P L Sbjct: 180 GTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGEEIKPGPHKIQGIGAGFIPANL 239 Query: 233 DQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVL 292 D LVD++I + NE+A++ ARRL EEG+L GISSGAA AAL++ K IVV+L Sbjct: 240 DLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGAAVAAALKLQEDESFTNKNIVVIL 299 Query: 293 PDFGERYLSTPLFADV 308 P GERYLST LFAD+ Sbjct: 300 PSSGERYLSTALFADL 315 >2EGU-A nrPDB Length = 308 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 186/302 (61%), Positives = 228/302 (75%), Gaps = 2/302 (0%) Query: 5 EDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPD 64 IT+LIG TP V+L R+ D AD+ KLEF NP +SVKDRI +AM++AAE+AG +KP Sbjct: 6 NSITELIGDTPAVKLNRIVDEDSADVYLKLEFMNPGSSVKDRIALAMIEAAEKAGKLKPG 65 Query: 65 TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSG 124 I+EPTSGNTGI LAMV AA+GY+ VL MP+TMSLERR LLRAYGAEL+LTPGA GM G Sbjct: 66 DTIVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAELVLTPGAQGMRG 125 Query: 125 AIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTIT 184 AIAKAEEL + + YF+PQQF+N ANP IHR+TT +E+ ++D VAGVGTGGTIT Sbjct: 126 AIAKAEELVR-EHGYFMPQQFKNEANPEIHRLTTGKEIVEQMGDQLDAFVAGVGTGGTIT 184 Query: 185 GVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVG 244 G +V++E P+ + AVEPA SPVLSGG+ GPH IQGIGAGFVP +LD + D +ITV Sbjct: 185 GAGKVLREAYPNIKIYAVEPADSPVLSGGKPGPHKIQGIGAGFVPDILDTSIYDGVITVT 244 Query: 245 NEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPL 304 E+A ARR AREEG+L GISSGAA AAL+VA+ GK ++ ++P GERYLSTPL Sbjct: 245 TEEAFAAARRAAREEGILGGISSGAAIHAALKVAKEL-GKGKKVLAIIPSNGERYLSTPL 303 Query: 305 FA 306 + Sbjct: 304 YQ 305 >2PQM-A nrPDB Length = 343 Score = 362 bits (929), Expect = e-100, Method: Composition-based stats. Identities = 156/310 (50%), Positives = 208/310 (67%), Gaps = 6/310 (1%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGA----VADIVAKLEFFNPANSVKDRIGVAMLQAAEQ 57 I +I + IG TPLV L VT+ I+ KLE+FNP +SVKDR+G ++ A + Sbjct: 12 RIYHNILETIGGTPLVELHGVTEHPRIKKGTRILVKLEYFNPMSSVKDRVGFNIVYQAIK 71 Query: 58 AGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTP 117 G +KP I+E TSGNTGIAL A GYR + MP TMS+ER+M+++A+GAELILT Sbjct: 72 DGRLKPGMEIIESTSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFGAELILTE 131 Query: 118 GADGMSGAIAKAEELAKTDQR-YFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAG 176 G GM GAI + ++ K + YFV QF NP N A H T A E+W DTDG+VDIVV+ Sbjct: 132 GKKGMPGAIEEVNKMIKENPGKYFVANQFGNPDNTAAHHYT-ANEIWEDTDGEVDIVVSA 190 Query: 177 VGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDL 236 VGT GT+ GVA+ +KE+K + +AVEP S VL G KGPH IQGIGAGF+P + ++ Sbjct: 191 VGTSGTVIGVAEKLKEKKKGIKIIAVEPEESAVLEGKAKGPHGIQGIGAGFIPDIYKKEF 250 Query: 237 VDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFG 296 VDEII + +DA +AR + + +G++ G+SSGAA +A L+ A +PEN GK IV+++P G Sbjct: 251 VDEIIPIKTQDAWKMARAVVKYDGIMCGMSSGAAILAGLKEAEKPENEGKTIVIIVPSCG 310 Query: 297 ERYLSTPLFA 306 ERYLST L+ Sbjct: 311 ERYLSTDLYK 320 >2EFY-A nrPDB Length = 304 Score = 360 bits (925), Expect = e-100, Method: Composition-based stats. Identities = 152/303 (50%), Positives = 204/303 (67%), Gaps = 4/303 (1%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDT- 65 + IG+TP+VRL +V + +A++ KLE NP S+KDR M++ AE+ G+++P + Sbjct: 3 VEGAIGKTPVVRLAKVVEPDMAEVWVKLEGLNPGGSIKDRPAWYMIKDAEERGILRPGSG 62 Query: 66 -IILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSG 124 +I+EPTSGNTGI LAM+ A+RGYR +LTMP MS ER+ +L+A+GAEL+LT M Sbjct: 63 QVIVEPTSGNTGIGLAMIAASRGYRLILTMPAQMSEERKRVLKAFGAELVLTDPERRMLA 122 Query: 125 AIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTIT 184 A +A L K + F+P QF+NPAN H TT E++ +G++D V G GTGGTIT Sbjct: 123 AREEALRL-KEELGAFMPDQFKNPANVRAHYETTGPELYEALEGRIDAFVYGSGTGGTIT 181 Query: 185 GVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVG 244 GV + +KER P + +AVEPA S VLSGG+ G H QG+G GF+P LD L+D +I V Sbjct: 182 GVGRYLKERIPHVKVIAVEPARSNVLSGGKMGQHGFQGMGPGFIPENLDLSLLDGVIQVW 241 Query: 245 NEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPL 304 EDA +ARRLAREEGL +G+SSG AALQVAR GK + + PD G +YLSTPL Sbjct: 242 EEDAFPLARRLAREEGLFLGMSSGGIVWAALQVAREL-GPGKRVACISPDGGWKYLSTPL 300 Query: 305 FAD 307 +A+ Sbjct: 301 YAE 303 >5XEM-A nrPDB Length = 310 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 145/303 (47%), Positives = 200/303 (66%), Gaps = 3/303 (0%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLI 61 S+A + LIG TPLV++ + D +I KLE NP S KDRI + M++ AE+ GLI Sbjct: 5 SLANSVIDLIGNTPLVKINNI-DTFGNEIYVKLEGSNPGRSTKDRIALKMIEEAEKEGLI 63 Query: 62 KPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG 121 DT+I+E TSGNTGI LAM+CA + Y+ + MP+TMS+ER L+RAYG E+ILT G+ G Sbjct: 64 DKDTVIIEATSGNTGIGLAMICAVKNYKLKIVMPDTMSIERIQLMRAYGTEVILTDGSLG 123 Query: 122 MSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGG 181 M + K EEL K +++YFVP QF N NP H TTAEE+ +D + KVD+ + G GTGG Sbjct: 124 MKACLEKLEELKKNEKKYFVPNQFTNVNNPKAHYETTAEEILKDLNNKVDVFICGTGTGG 183 Query: 182 TITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGA--GFVPPVLDQDLVDE 239 + +G A+ +KE+ P+ + VEPA+SP+LS G GPH IQG+G G +P V D L D+ Sbjct: 184 SFSGTAKKLKEKLPNIKTFPVEPASSPLLSKGYIGPHKIQGMGMSIGGIPAVYDGSLADD 243 Query: 240 IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERY 299 I+ ++DA + R L+ +EG+L GIS+GA AAL ++ + G IVV+ D GE+Y Sbjct: 244 ILVCEDDDAFEMMRELSFKEGILGGISTGATFKAALDYSKENADKGLKIVVLSTDSGEKY 303 Query: 300 LST 302 LS Sbjct: 304 LSN 306 >2BHS-A nrPDB Length = 303 Score = 359 bits (921), Expect = 1e-99, Method: Composition-based stats. Identities = 126/304 (41%), Positives = 181/304 (59%), Gaps = 10/304 (3%) Query: 4 AEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKP 63 + Q IG TPLV+L+R+ +++ KLE NPA SVKDR ++M+ AE+ G IKP Sbjct: 1 MSTLEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKP 60 Query: 64 DTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMS 123 +++E TSGNTGIALAM+ A +GYR L MP+ MS ERR +RAYGAELIL GM Sbjct: 61 GDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGME 120 Query: 124 GAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTI 183 GA A E+A + + QF NP NP H TT E+W+ T G++ V+ +GT GTI Sbjct: 121 GARDLALEMANRGEGK-LLDQFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTGTI 179 Query: 184 TGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITV 243 TGV++ ++E+ V ++P + G ++ P ++P + + LVDE++ + Sbjct: 180 TGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWP-------TEYLPGIFNASLVDEVLDI 232 Query: 244 GNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTP 303 DA N R LA EG+ G+SSG A AL+VA+ N ++V ++ D G+RYLST Sbjct: 233 HQRDAENTMRELAVREGIFCGVSSGGAVAGALRVAK--ANPDAVVVAIICDRGDRYLSTG 290 Query: 304 LFAD 307 +F + Sbjct: 291 VFGE 294 >6AHI-A nrPDB Length = 314 Score = 358 bits (920), Expect = 1e-99, Method: Composition-based stats. Identities = 128/307 (41%), Positives = 189/307 (61%), Gaps = 4/307 (1%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVAD--IVAKLEFFNPANSVKDRIGVAMLQAAEQA 58 M I + IGRTP+ + + I AKLE NP SVKDR+G ++ + Sbjct: 1 MMIITTMQDAIGRTPVFKFTNKDYPIPLNSAIYAKLEHLNPGGSVKDRLGQYLIGEGFKT 60 Query: 59 GLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPG 118 G I T I+EPT+GNTGIALA+V + + +PE S E++ ++RA GA +I TP Sbjct: 61 GKITSKTTIIEPTAGNTGIALALVAIKHHLKTIFVVPEKFSTEKQQIMRALGALVINTPT 120 Query: 119 ADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVG 178 ++G+SGAI K++ELA++ ++P QFENP NPA + T A E+ ++ + VAG+G Sbjct: 121 SEGISGAIKKSKELAESIPDSYLPLQFENPDNPAAYYHTLAPEIVQELGTNLTSFVAGIG 180 Query: 179 TGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVD 238 +GGT G A+ +KER P+ R + VEP S +L+GG+ GPH I+GIG F+PP + +D Sbjct: 181 SGGTFAGTARYLKERIPAIRLIGVEPEGS-ILNGGEPGPHEIEGIGVEFIPPFFENLDID 239 Query: 239 EIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGER 298 T+ +E+ + R+LA++ GLLVG SSGAA VAAL+ A+R G ++ + PD +R Sbjct: 240 GFETISDEEGFSYTRKLAKKNGLLVGSSSGAAFVAALKEAQRL-PEGSQVLTIFPDVADR 298 Query: 299 YLSTPLF 305 YLS ++ Sbjct: 299 YLSKGIY 305 >2JC3-A nrPDB Length = 303 Score = 357 bits (916), Expect = 4e-99, Method: Composition-based stats. Identities = 128/304 (42%), Positives = 183/304 (60%), Gaps = 10/304 (3%) Query: 4 AEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKP 63 + Q IG TPLV+L+R+ ++I KLE NPA SVKDR ++M+ AE+ G IKP Sbjct: 1 MNTLEQTIGNTPLVKLQRIGPDNGSEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEIKP 60 Query: 64 DTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMS 123 +++E TSGNTGIALAM+ A +GYR L MP+ MS ERR +RAYGAELIL GM Sbjct: 61 GDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGME 120 Query: 124 GAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTI 183 GA A +++ + + QF NP NP H TT E+WR T G++ V+ +GT GTI Sbjct: 121 GARDLALAMSERGEGK-LLDQFNNPDNPYAHYTTTGPEIWRQTSGRITHFVSSMGTTGTI 179 Query: 184 TGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITV 243 TGV++ ++E++ V ++P + G ++ P A ++P + + LVDE++ + Sbjct: 180 TGVSRFLREQEKPVTIVGLQPEEGSSIPGIRRWP-------AEYMPGIFNASLVDEVLDI 232 Query: 244 GNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTP 303 DA N R LA EG+ G+SSG A AL+VAR G ++V ++ D G+RYLST Sbjct: 233 HQNDAENTMRELAVREGIFCGVSSGGAVAGALRVAR--ATPGAIVVAIICDRGDRYLSTG 290 Query: 304 LFAD 307 +F + Sbjct: 291 VFGE 294 >4OFX-A nrPDB Length = 319 Score = 353 bits (906), Expect = 6e-98, Method: Composition-based stats. Identities = 134/306 (43%), Positives = 195/306 (63%), Gaps = 4/306 (1%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLI 61 + ++I Q+IG+TP+VRL R+ ++ K EF NP SVKDRIG AM+++AE+ G I Sbjct: 4 MVLDNILQVIGKTPVVRLHRIGQSLPCELYGKCEFLNPGGSVKDRIGAAMIESAEKQGKI 63 Query: 62 KPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA-- 119 KP ++EPTSGNTGI +A+ A +GYR ++TMPE MS E++++L A GA + TP Sbjct: 64 KPGDTLIEPTSGNTGIGIALAGAVKGYRVIITMPEKMSHEKQVVLEALGATIYRTPTEAA 123 Query: 120 -DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVG 178 D I+ A+ L + ++ Q+ N NP IH TT +E+ D + +VV GVG Sbjct: 124 YDDPESHISLAKRLNQEIPNSYILDQYSNAENPDIHYQTTGQEILDDMGENLSMVVMGVG 183 Query: 179 TGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVD 238 TGGTI GVA+ +KE PS + + V+P S + G + P+ ++GIG F+P VLD +L+D Sbjct: 184 TGGTIIGVAKKLKEVNPSIQIIGVDPIGSILGGGDEIKPYLVEGIGYDFIPEVLDNNLID 243 Query: 239 EIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGER 298 E I + ++D+ +ARRL REEGLLVG SSG+A AA Q A+R + G+ +V+LPD Sbjct: 244 EYIKINDKDSFLMARRLIREEGLLVGGSSGSAVWAACQAAQRLK-EGERCLVILPDAIRN 302 Query: 299 YLSTPL 304 YL+ + Sbjct: 303 YLTKFV 308 >5OHX-A nrPDB Length = 504 Score = 353 bits (905), Expect = 8e-98, Method: Composition-based stats. Identities = 135/312 (43%), Positives = 192/312 (61%), Gaps = 10/312 (3%) Query: 2 SIAEDITQLIGRTPLVRLRRV--TDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAG 59 I DI IG+TPL++L + + G +I AK EF NP SVKDRI M+Q AE G Sbjct: 34 KIMPDILTAIGQTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAEDKG 93 Query: 60 LIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA 119 L+KP I+EPTSGNTGI LAM A RGY+C++ MPE MS E+ L A GA++I TP Sbjct: 94 LLKPGCTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTE 153 Query: 120 ---DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAG 176 I+ A++L K + Q+ NP NP H TA E+W+ +GK+D +VAG Sbjct: 154 ASWHSPEAHISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLVAG 213 Query: 177 VGTGGTITGVAQVIKERKPSARFVAVEPAASPV----LSGGQKGPHPIQGIGAGFVPPVL 232 GTGGTI+G+ + +KE P+ + +AV+P S + S + G + ++GIG F+P VL Sbjct: 214 AGTGGTISGIGRKLKELSPNIKIIAVDPKGSILDPSSDSQNEVGFYEVEGIGYDFIPTVL 273 Query: 233 DQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVL 292 D++++D+ I + ++LN AR L R+EGLL G SSGAA +AAL++A+ K +V++L Sbjct: 274 DRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAALIAALKIAKDI-PEEKRMVIIL 332 Query: 293 PDFGERYLSTPL 304 PD YL+ + Sbjct: 333 PDGIRNYLTKFV 344 >3PC3-A nrPDB Length = 527 Score = 350 bits (899), Expect = 4e-97, Method: Composition-based stats. Identities = 134/312 (42%), Positives = 184/312 (58%), Gaps = 11/312 (3%) Query: 3 IAEDITQLIGRTPLVRLRRV--TDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 I +I ++IG TPLV+L + +DG ++ AK EF NP SVKDRIG M+Q AE+ GL Sbjct: 50 ITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGL 109 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA- 119 +KP I+EPTSGNTGI LAM CA +GY+C++ MPE MS E+ LR GA++I TP Sbjct: 110 LKPGYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEA 169 Query: 120 --DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGV 177 D G I A++L + V Q+ N NP H TA E+ D KVD++V Sbjct: 170 AYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSA 229 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPV-----LSGGQKGPHPIQGIGAGFVPPVL 232 GT GTI+G+ + IKE+ PS + V V+P S + L+ + ++GIG F P V Sbjct: 230 GTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPPTVF 289 Query: 233 DQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVL 292 D +VD +G+ D ++RRL EEGLL G SSG A AAL+ AR+ + G+ VV+L Sbjct: 290 DDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHARKLK-KGQRCVVIL 348 Query: 293 PDFGERYLSTPL 304 PD Y++ + Sbjct: 349 PDGIRNYMTKFV 360 >5XCN-X nrPDB Length = 350 Score = 339 bits (869), Expect = 1e-93, Method: Composition-based stats. Identities = 175/317 (55%), Positives = 216/317 (68%), Gaps = 10/317 (3%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 M+I D + IG TPLVRL+ G ++V K+E NP+ SVK RIG M+ AE+ G Sbjct: 35 MAIYADNSYSIGNTPLVRLKHF--GHNGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDGT 92 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 + I++ TSGNTGIALA V AARGY+ LTMPETMSLER+ LL G L+LT GA Sbjct: 93 LTKGKEIVDATSGNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEGAK 152 Query: 121 GMSGAIAKAEELAKTDQ-RYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGT 179 G GAIAKAEE+ +D RY + +QFENPANP IHR TT E+W+DTDGKVD+VVAGVGT Sbjct: 153 GAKGAIAKAEEIVASDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAGVGT 212 Query: 180 GGTITGVAQVIK-ERKPSARFVAVEPAASPVLSGG------QKGPHPIQGIGAGFVPPVL 232 GG+ITG+++ IK + VAVEP SPV+S + GPH IQGIGAGF+P L Sbjct: 213 GGSITGISRAIKLDFGKQITSVAVEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNL 272 Query: 233 DQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVL 292 D ++D + TV ++ AL ARRL EEG+L GISSGAA AA ++A+ PE A KLIVV+L Sbjct: 273 DLSIIDRVETVDSDTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVIL 332 Query: 293 PDFGERYLSTPLFADVA 309 P ERYLST LF + Sbjct: 333 PSASERYLSTALFEGIE 349 >6C2H-A nrPDB Length = 375 Score = 337 bits (864), Expect = 4e-93, Method: Composition-based stats. Identities = 116/318 (36%), Positives = 176/318 (55%), Gaps = 18/318 (5%) Query: 5 EDITQLIGRTPLVRLRRVTDGAVAD--IVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 62 ++ L+G TPL+ L+++ I AKLE +NP S+KDRI +M++ AE +G I Sbjct: 34 HNVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASGRIH 93 Query: 63 PD-TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA-- 119 P + ++EPTSGNTGI LA++ A +GYR ++T+PE MS E+ +L+A GAE+I TP A Sbjct: 94 PSRSTLIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAA 153 Query: 120 -DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTD-----GKVDIV 173 D I A++L K + Q+ N NP H T E+ R + + V Sbjct: 154 WDSPESHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAV 213 Query: 174 VAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPV-----LSGGQKGPHPIQGIGAGFV 228 VAG GTGGTI+G+++ +KE+ + V +P S + L+ + ++GIG FV Sbjct: 214 VAGAGTGGTISGISKYLKEQNDKIQIVGADPFGSILAQPENLNKTDITDYKVEGIGYDFV 273 Query: 229 PPVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVAR-RPE-NAGK 286 P VLD+ L+D ++ + AR+L EG+LVG SSG+A A ++ PE Sbjct: 274 PQVLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYCEDHPELTEDD 333 Query: 287 LIVVVLPDFGERYLSTPL 304 +IV + PD YL+ + Sbjct: 334 VIVAIFPDSIRSYLTKFV 351 >3X43-A nrPDB Length = 332 Score = 331 bits (849), Expect = 2e-91, Method: Composition-based stats. Identities = 147/311 (47%), Positives = 203/311 (65%), Gaps = 4/311 (1%) Query: 1 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGL 60 M + I IGRTP+VRL+R+ + + K+E FNP SVKDR+ ++++ AE GL Sbjct: 1 MPLFNSILDTIGRTPIVRLQRMAPEHTS-VYVKVESFNPGGSVKDRLALSVVLDAEAKGL 59 Query: 61 IKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 +KP I+E TSGN GIALAMV AARGYR V M +T S+ERR L+RAYG +L+L PG Sbjct: 60 LKPGDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLVLFPGHL 119 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGK-VDIVVAGVGT 179 G G A+ELA+ +F +QF+NPANP+ HR TTA E+ D GK +D V G GT Sbjct: 120 GSKGGNLIADELAEK-YGWFRARQFDNPANPSYHRETTASEILADFAGKRLDHFVTGFGT 178 Query: 180 GGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDE 239 GT+TGV Q+++ +P R VA+EP+ + +L+ G+ PH IQG+ FVP VLD+ ++D+ Sbjct: 179 TGTLTGVGQMLRVARPEVRVVALEPSNAAMLARGEWSPHQIQGLAPNFVPGVLDRSVIDD 238 Query: 240 IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERY 299 ++T+ A + +RRLA EEG+ GIS+GA AL +A G +++ +LPD GERY Sbjct: 239 LVTMDEVTARDTSRRLAAEEGIFAGISAGATVATALSIAEH-APEGTVLLAMLPDTGERY 297 Query: 300 LSTPLFADVAD 310 LST LF V + Sbjct: 298 LSTFLFDGVDE 308 >5B1I-A nrPDB Length = 311 Score = 323 bits (828), Expect = 6e-89, Method: Composition-based stats. Identities = 129/308 (41%), Positives = 185/308 (60%), Gaps = 3/308 (0%) Query: 2 SIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLI 61 + + + +LIG TPL+ L + + I AKLE FNP S+ DR+G +++ Q G + Sbjct: 1 MLIQHVQELIGHTPLMALP-IEVPNHSHIYAKLEMFNPGGSIADRLGAYLIEDGLQRGRV 59 Query: 62 KPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG 121 T I+EPT+GNTGI LA+ A R +L +PE S+E+++L++A GAE++ TP +G Sbjct: 60 NAKTTIIEPTAGNTGIGLALATQAHHLRTILVVPEKFSMEKQVLMQALGAEIVHTPSEEG 119 Query: 122 MSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGG 181 + GAI KAE LA T +VP QF+NPANPA + T A E+ D + VAG G+GG Sbjct: 120 IKGAIRKAEALAATISNSYVPMQFKNPANPAAYYHTLAPEILADMPAPITAFVAGAGSGG 179 Query: 182 TITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEII 241 T GVA ++ + + + V VEP S +L+GG H +GIG F+PP DQ +D+ + Sbjct: 180 TFAGVAAYLQAQDSATKAVVVEPEGS-ILNGGPAHAHRTEGIGVEFIPPFFDQVRIDQTL 238 Query: 242 TVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLS 301 T+ + DA R LAR+ GLL+G SSGAA A+LQ+A A IV + PD ERYLS Sbjct: 239 TIADNDAFAQVRHLARDHGLLIGSSSGAALAASLQLATNL-PANSHIVTIFPDSSERYLS 297 Query: 302 TPLFADVA 309 ++ + Sbjct: 298 QKIYTKLE 305 >5JJC-A nrPDB Length = 342 Score = 311 bits (796), Expect = 3e-85, Method: Composition-based stats. Identities = 118/313 (37%), Positives = 173/313 (55%), Gaps = 14/313 (4%) Query: 3 IAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 62 + + IG TPL+RL + ++ DI K EF NP SVKDR + +++ AE+ GL++ Sbjct: 1 MFNSVLDTIGNTPLIRLSKASELTGCDIYGKAEFLNPGQSVKDRAALYIIRDAEKRGLLR 60 Query: 63 PDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD-- 120 P +I+E T+GNTGI L MV A GYR + +PET S E++ LR GAELI P A Sbjct: 61 PGGVIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELIEVPAAPYR 120 Query: 121 GMSGAI----AKAEELAKTDQRYFV-PQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVA 175 + A+ AE+LAKT+ + QF+N N H TTA+E+WRDT ++D VA Sbjct: 121 NPNNAVRLSGRLAEQLAKTEPNGAIWANQFDNTVNRQAHIETTAQEIWRDTSDQIDGFVA 180 Query: 176 GVGTGGTITGVAQVIKERKPSARFVAVEPAASPV---LSGGQ---KGPHPIQGIGAGFVP 229 VG+GGT+ G A +KER + + +P + + + G+ +G +GIG G + Sbjct: 181 AVGSGGTLAGTAIGLKERNHNIKIALADPHGAALHAFYTTGELKAEGDSITEGIGQGRIT 240 Query: 230 PVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIV 289 L+ D + + +AL++ L EEGL +G SSG A+++A+ G IV Sbjct: 241 ANLEGFTPDFSYQIPDAEALDILFALVEEEGLCLGGSSGINIAGAIRLAKDL-GPGHTIV 299 Query: 290 VVLPDFGERYLST 302 VL D+G RY S Sbjct: 300 TVLCDYGNRYQSK 312 >5D84-A nrPDB Length = 326 Score = 304 bits (780), Expect = 2e-83, Method: Composition-based stats. Identities = 98/300 (32%), Positives = 160/300 (53%), Gaps = 8/300 (2%) Query: 5 EDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPD 64 + + +G+TP+V+L ++ ++ AKLE+ NP S+KDR +++ + GLI + Sbjct: 10 DSLLDSVGQTPMVQLHQLFP--KHEVFAKLEYMNPGGSMKDRPAKYIIEHGIKHGLITEN 67 Query: 65 TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGA--ELILTPGADG- 121 T ++E TSGN GIALAM+ +G + + +S ++++YGA E++ P A G Sbjct: 68 THLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGANVEMVEEPDAHGG 127 Query: 122 -MSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 180 + IAK +EL T + Q+ N N H E+ +D VA V T Sbjct: 128 YLMTRIAKVQELLATIDDAYWINQYANELNWQSHYHGAGTEIVETIKQPIDYFVAPVSTT 187 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 240 G+I G+++ IKE P+A+ VAV+ S V+ G + + GIGA VP +L++ ++++ Sbjct: 188 GSIMGMSRKIKEVHPNAQIVAVDAKGS-VIFGDKPINRELPGIGASRVPEILNRSEINQV 246 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 I V + + R+L EG+ G S+G+ A Q+ E G IV +LPD G+RYL Sbjct: 247 IHVDDYQSALGCRKLIDYEGIFAGGSTGSIIAAIEQLITSIE-EGATIVTILPDRGDRYL 305 >5B55-A nrPDB Length = 340 Score = 300 bits (768), Expect = 5e-82, Method: Composition-based stats. Identities = 114/306 (37%), Positives = 174/306 (56%), Gaps = 7/306 (2%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 + L+G+TP++ L G I K E +N S+KDR+ L+ A + IK Sbjct: 13 LENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAP 72 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD-GMSGA 125 I+E TSGNTGIA + + A G+ ++ MP+ MS ER+ L+R++GA++IL + G G+ Sbjct: 73 IVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGS 132 Query: 126 IAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEV---WRDTDGKVDIVVAGVGTGGT 182 I K +E AK + ++P QF N N H E+ + + +D VAGVGTGGT Sbjct: 133 IEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGT 192 Query: 183 ITGVAQVIKERKPSARFVAVEPAASPVLSGGQK-GPHPIQGIGAGFVPPVLDQDLVDEII 241 + G+ + IKE +A+ +EP SP LS G K H I+GI F+P ++ D +D ++ Sbjct: 193 VMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISNEFIPDLVKLDKLDNVV 252 Query: 242 TVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLS 301 +V + DA+ +A++LA + GL VGISSGA + AL + + +IV V PD ++YLS Sbjct: 253 SVDDGDAIVMAQKLA-KCGLGVGISSGANFIGALMLQNKL-GKDSVIVTVFPDDNKKYLS 310 Query: 302 TPLFAD 307 T L + Sbjct: 311 TDLMRE 316 >5I7O-A nrPDB Length = 326 Score = 298 bits (762), Expect = 3e-81, Method: Composition-based stats. Identities = 123/319 (38%), Positives = 177/319 (55%), Gaps = 17/319 (5%) Query: 1 MSIAEDITQLIGRTPLVRLRRVT-------DGAVADIVAKLEFFNPANSVKDRIGVAMLQ 53 M+ + + Q +G TPLV L+R++ DG + AKLE NP S+KDR V M++ Sbjct: 4 MARYDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIE 63 Query: 54 AAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAEL 113 AE GL++P ILEPTSGNTGI+LAM +GYR + MPE S+ERR LL YGA++ Sbjct: 64 QAEADGLLRPGATILEPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQI 123 Query: 114 ILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIV 173 I + G + A+A A+ELA T+ + + Q+ NPAN H T E+ D + Sbjct: 124 IFSAAEGGSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADLPE-ITHF 182 Query: 174 VAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLD 233 VAG+GT GT+ G + ++E + + VA EP +G + ++ + GFVP + D Sbjct: 183 VAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYG-------EGVYALRNMDEGFVPELYD 235 Query: 234 QDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKL--IVVV 291 +++ +VG DA+ R L EG+ GIS+GA AAL V AG+ I +V Sbjct: 236 PEILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALV 295 Query: 292 LPDFGERYLSTPLFADVAD 310 + D G +YLST +A D Sbjct: 296 VADAGWKYLSTGAYAGSLD 314 >5X2L-A nrPDB Length = 348 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 80/313 (25%), Positives = 133/313 (42%), Gaps = 21/313 (6%) Query: 6 DITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDT 65 +I I TP++ + ++ K E F S K R + +++ L + Sbjct: 18 NIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPK 77 Query: 66 IILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGA 125 ++ +SGN G AL G + +P+T +++ ++AYGA ++ +D Sbjct: 78 AVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESREN 137 Query: 126 IAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITG 185 +AK +T+ P Q PA + T A EV VD +V VG GG + G Sbjct: 138 VAK-RVTEETEGIMVHPNQ--EPA-VIAGQGTIALEVLNQVP-LVDALVVPVGGGGMLAG 192 Query: 186 VAQVIKERKPSARFVAVEPA-ASPVLSGGQKGP-----HPIQGIGAGFVPPV------LD 233 +A +K KPS + A EP+ A KG +P + I G + + Sbjct: 193 IAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPII 252 Query: 234 QDLVDEIITVGNEDALNVARRLAREE-GLLVGISSGAATVAAL-QVARRPENAGKLIVVV 291 +DLVD+I TV ++ + A +L E LL+ ++G A L Q + K I +V Sbjct: 253 RDLVDDIFTVTEDE-IKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIV 311 Query: 292 LPDFGERYLSTPL 304 L G L++ + Sbjct: 312 L-SGGNVDLTSSI 323 >3VSD-A nrPDB Length = 389 Score = 222 bits (566), Expect = 2e-58, Method: Composition-based stats. Identities = 84/292 (28%), Positives = 139/292 (47%), Gaps = 16/292 (5%) Query: 14 TPLVRLRRVTDGAVADIVAKLEFFNPAN-SVKDRIGVAMLQAAEQAGLIKPDTIILEPTS 72 TPLVR R+ + KLE++NP + SV DR V ++ + ++ +++ + TS Sbjct: 97 TPLVR-SRLQLPNGVRVWLKLEWYNPFSLSVADRPAVEIISRLSRR--VEKGSLVADATS 153 Query: 73 GNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEEL 132 N G+AL+ V GYR + +P ++L R GA++I+ P A + + + Sbjct: 154 SNFGVALSAVARLYGYRARVYLPGAAEEFGKLLPRLLGAQVIVDPEAPSTVHLLPRVMKD 213 Query: 133 AKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDT---DGKVDIVVAGVGTGGTITGVAQV 189 +K + V QF N AN H TA E++ + + V +GT G ++ A Sbjct: 214 SKNEGFVHV-NQFYNDANFEAHMRGTAREIFVQSRRGGLALRGVAGSLGTSGHMSAAAFY 272 Query: 190 IKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGNEDAL 249 ++ PS R V V+PA + G I+ + G + + D+ + V E+A+ Sbjct: 273 LQSVDPSIRAVLVQPAQGDSIPG-------IRRVETGMLW-INMLDISYTLAEVTLEEAM 324 Query: 250 NVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLS 301 +AR +GL++G S GAA A + A + VVV+PD G +YLS Sbjct: 325 EAVVEVARSDGLVIGPSGGAAVKALAKKAAEGDLEPGDYVVVVPDTGFKYLS 376 >6NMX-A nrPDB Length = 354 Score = 213 bits (543), Expect = 7e-56, Method: Composition-based stats. Identities = 74/310 (23%), Positives = 125/310 (40%), Gaps = 28/310 (9%) Query: 12 GRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPT 71 G TPL+ L ++++ ++ K E NP S KDR V + A++ G + I+ + Sbjct: 29 GNTPLIHLPKLSEQLGIELHVKTEGVNPTGSFKDRGMVMAVAKAKEEG----NDTIMCAS 84 Query: 72 SGNTGIALAMVCAARGYRCVLTMPE-TMSLERRMLLRAYGAELILTPGADGMSGAIAKAE 130 +GNT A A A +C++ +P ++ + YGAE+I G A+ Sbjct: 85 TGNTSAAAAAYAARANMKCIVIIPNGKIAFGKLAQAVMYGAEIIAIDG--NFDDALKIVR 142 Query: 131 ELAKTDQRYFVPQQFENPANPA--IHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQ 188 + + V N NP + T A EV D++ VG G I+ + Sbjct: 143 SICEKSPIALV-----NSVNPYRLEGQKTAAFEVCEQLGEAPDVLAIPVGNAGNISAYWK 197 Query: 189 VIKERK-------PSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLD------QD 235 KE P R E +A+ V + + P I P D ++ Sbjct: 198 GFKEYHEKNGTSLPKMRGFEAEGSAAIVRNEVIENPETIATAIRIGNPASWDKAVKAAEE 257 Query: 236 LVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPE-NAGKLIVVVLPD 294 +I V +++ L+ + +AREEG+ S A+ L+ + E G +V VL Sbjct: 258 SNGKIDEVTDDEILHAYQLIAREEGVFAEPGSCASIAGVLKQVKSGEIPKGSKVVAVLTG 317 Query: 295 FGERYLSTPL 304 G + +T + Sbjct: 318 NGLKDPNTAV 327 >5EY5-B nrPDB Length = 399 Score = 211 bits (537), Expect = 4e-55, Method: Composition-based stats. Identities = 80/344 (23%), Positives = 137/344 (39%), Gaps = 54/344 (15%) Query: 7 ITQLIGR-TPLVRLRRVT-DGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPD 64 + +GR TPL +T D A I K E N + K + A++ G Sbjct: 43 LRDYVGRPTPLYFAENLTKDLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMG---KK 99 Query: 65 TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRML----LRAYGAELI-LTPGA 119 +I E +G G+A A V A G CV+ M +ER+ L ++ GA++ +T G+ Sbjct: 100 RVIAETGAGQHGVATATVAAMFGLECVVYMG-AEDIERQALNVFRMKLLGAKVRPVTSGS 158 Query: 120 DGMSGAIAKA--EELAKTDQRYFVPQQFENPA-NPAIHR---VTTAEEVWRDT----DGK 169 + AI +A + + + +++ P P + R EE + Sbjct: 159 RTLKDAINEAMRDWVTNVEDTFYIIGSVVGPHPYPMMVRDFQSVIGEEARQQILEKEGRL 218 Query: 170 VDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKG------PHPIQG- 222 D +VA VG G G+ + + S R + VE A + +G P + G Sbjct: 219 PDAIVACVGGGSNAMGIFHPFIDDE-SVRLIGVEAAGKGIETGKHAATLSAGRPGVLHGA 277 Query: 223 -----------------IGAGFVPP-------VLDQDLVDEIITVGNEDALNVARRLARE 258 I AG P L E ++V +++AL + L+R Sbjct: 278 MTYLLQDEDGQIIEAHSISAGLDYPGVGPEHAYLKDTGRAEYVSVTDDEALEAFQLLSRT 337 Query: 259 EGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLST 302 EG++ + S A A+++A + ++IVV L G++ ++T Sbjct: 338 EGIIPALESSHAVAYAMKLAPEL-SKDQIIVVNLSGRGDKDVNT 380 >3L6C-A nrPDB Length = 339 Score = 199 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 81/319 (25%), Positives = 136/319 (42%), Gaps = 21/319 (6%) Query: 6 DITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDT 65 +I + TP++ + A ++ K E F S K R + ++ L Sbjct: 18 NIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPK 77 Query: 66 IILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGA 125 ++ +SGN G AL G + +P+T +++ ++AYGA ++ + +D Sbjct: 78 AVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESREN 137 Query: 126 IAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITG 185 +A+ + +T+ P Q PA + T A EV VD +V VG GG + G Sbjct: 138 VAQ-RIIQETEGILVHPNQ--EPA-VIAGQGTIALEVLNQVP-LVDALVVPVGGGGMVAG 192 Query: 186 VAQVIKERKPSARFVAVEPA-ASPVLSGGQKGP-----HPIQGIGAGFVPPV------LD 233 +A IK KPS + A EP+ A KG HP + I G + + Sbjct: 193 IAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPII 252 Query: 234 QDLVDEIITVGNEDALNVARRLAREE-GLLVGISSGAATVAAL-QVARRPENAGKLIVVV 291 +DLVD++ TV ++ + A +L E LL+ ++G A L Q + K I +V Sbjct: 253 RDLVDDVFTVTEDE-IKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIV 311 Query: 292 LPDFGERYLSTPLFADVAD 310 L G L++ + A+ Sbjct: 312 L-SGGNVDLTSLSWVKQAE 329 >1TDJ-A nrPDB Length = 514 Score = 193 bits (492), Expect = 6e-50, Method: Composition-based stats. Identities = 81/306 (26%), Positives = 135/306 (44%), Gaps = 27/306 (8%) Query: 14 TPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSG 73 TPL ++ +++ I+ K E P +S K R AM+ + + ++ ++G Sbjct: 32 TPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGLTEE---QKAHGVITASAG 88 Query: 74 NTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEELA 133 N +A A G + ++ MP + + +R +G E++L A AKA EL+ Sbjct: 89 NHAQGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLLH--GANFDEAKAKAIELS 146 Query: 134 KTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIKER 193 + +VP F++P + T A E+ + D +D V VG GG GVA +IK+ Sbjct: 147 QQQGFTWVPP-FDHPM-VIAGQGTLALELLQQ-DAHLDRVFVPVGGGGLAAGVAVLIKQL 203 Query: 194 KPSARFVAVEPAASPVLSGGQKGPHPI---------QGIGA---GFVPPVLDQDLVDEII 241 P + +AVE S L HP+ +G+ G L Q+ +D+II Sbjct: 204 MPQIKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDII 263 Query: 242 TVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPEN-AGKLIVVVLPDF----- 295 TV + DA+ A + E+ V SGA +A ++ N G+ + +L Sbjct: 264 TV-DSDAICAAMKDLFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSGANVNFH 322 Query: 296 GERYLS 301 G RY+S Sbjct: 323 GLRYVS 328 >5OCW-B nrPDB Length = 442 Score = 188 bits (477), Expect = 3e-48, Method: Composition-based stats. Identities = 81/340 (23%), Positives = 123/340 (36%), Gaps = 59/340 (17%) Query: 14 TPLVRLRRVTDGAV-ADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTS 72 +PL R++ A A I K E N S K + A + G + +I E + Sbjct: 102 SPLYEATRLSQHAGSARIFLKREDLNHTGSHKINNVLGQALLARRMGKTR---VIAETGA 158 Query: 73 GNTGIALAMVCAARGYRCVLTMPETMSLERRML----LRAYGAELI-LTPGADGMSGAIA 127 G G+A A CA G CV+ M + R+ L +R GAE++ + G+ + AI Sbjct: 159 GQHGVATATACALLGLDCVIYMGG-IDTARQALNVARMRLLGAEVVAVQTGSKTLKDAIN 217 Query: 128 KA--EELAKTDQRYFVPQQFENPANPAI-------HRVTTAEE----VWRDTDGKVDIVV 174 +A + +A D Y+ F A P + E + D VV Sbjct: 218 EAFRDWVANADNTYYC---FGTAAGPHPFPTMVRDFQRIIGMEARVQIQGQAGRLPDAVV 274 Query: 175 AGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKG------PHPIQG------ 222 A VG G G+ + P R V E A V +G P G Sbjct: 275 ACVGGGSNAIGIFHAFLD-DPGVRLVGFEAAGDGVETGRHAATFTAGSPGAFHGSFSYLL 333 Query: 223 ------------IGAGFVPP-------VLDQDLVDEIITVGNEDALNVARRLAREEGLLV 263 I AG P L + + + + +A++ L R EG++ Sbjct: 334 QDEDGQTIESHSISAGLDYPGVGPEHAWLKEAGRVDYRPITDSEAMDAFGLLCRMEGIIP 393 Query: 264 GISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTP 303 I S A AL++ G +IVV L G++ + T Sbjct: 394 AIESAHAVAGALKLGVEL-GRGAVIVVNLSGRGDKDVETA 432 >6AMI-A nrPDB Length = 396 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 72/338 (21%), Positives = 124/338 (36%), Gaps = 53/338 (15%) Query: 14 TPLVRLRRVTDG-AVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTS 72 TPL +R+T+ A + K E + K + A A + +I E + Sbjct: 51 TPLYYAKRLTEKIGGAKVYLKREDLVHGGAHKTN---NAIGQALLAKFMGKTRLIAETGA 107 Query: 73 GNTGIALAMVCAARGYRCVLTMPETMSLERRML----LRAYGAELI-LTPGADGMSGAIA 127 G G+A AM A G + + M +ER+ + ++ GA +I + G+ + AI Sbjct: 108 GQHGVATAMAGALLGMKVDIYMG-AEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAIN 166 Query: 128 KA--EELAKTDQRYFVPQQFENPA-NPAIHR---VTTAEE----VWRDTDGKVDIVVAGV 177 +A + +A + +++ P P I R E + D++VA V Sbjct: 167 EALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACV 226 Query: 178 GTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGP-------------------- 217 G G G+ + V VE + SG Sbjct: 227 GGGSNAMGIFYPF-VNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVSHGMLSYFLQDE 285 Query: 218 ----HPIQGIGAGFVPP-------VLDQDLVDEIITVGNEDALNVARRLAREEGLLVGIS 266 P I G P L + E + V +E+AL L+R EG++ + Sbjct: 286 EGQIKPSHSIAPGLDYPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSRTEGIIPALE 345 Query: 267 SGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPL 304 S A A+++A+ + ++I+V L G++ L L Sbjct: 346 SAHAVAYAMKLAKEM-SRDEIIIVNLSGRGDKDLDIVL 382 >5KIN-B nrPDB Length = 407 Score = 173 bits (439), Expect = 8e-44, Method: Composition-based stats. Identities = 75/343 (21%), Positives = 125/343 (36%), Gaps = 55/343 (16%) Query: 7 ITQLIGR-TPLVRLRRVTDG-AVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPD 64 + Q +GR TPL + +T A I K E N + K + + A++ G Sbjct: 52 LRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLAKRMG---KK 108 Query: 65 TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRML----LRAYGAELI-LTPGA 119 II E +G G+A A A C + M E ++R+ L + GA++ +T G+ Sbjct: 109 KIIAETGAGQHGVATATAAALFNMECTIYMGE-EDVKRQALNVFRMELLGAKVEAVTDGS 167 Query: 120 DGMSGAIAKAE--ELAKTDQRYFVPQQFENPAN-PAIHR---VTTAEEVWRDTDGK---- 169 + A+ A +A D +++ P P I R E + Sbjct: 168 RVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDLTGRD 227 Query: 170 -VDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKG------PHPIQG 222 D +VA VG G G+ E + S E A V + P + G Sbjct: 228 LPDALVACVGGGSNAIGLFHPFVEDE-SVAMYGTEAAGLGVDTEHHAATLTKGRPGVLHG 286 Query: 223 ------------------IGAGFVPPVLDQD-------LVDEIITVGNEDALNVARRLAR 257 I AG P + + + V +E+AL + L+R Sbjct: 287 SLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTDEEALEGFQLLSR 346 Query: 258 EEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 EG++ + S A A+++A+ +IV L G++ + Sbjct: 347 VEGIIPALESSHAIAFAVKLAKELGPEKSMIVC-LSGRGDKDV 388 >6HUL-B nrPDB Length = 425 Score = 172 bits (437), Expect = 1e-43, Method: Composition-based stats. Identities = 78/350 (22%), Positives = 127/350 (36%), Gaps = 64/350 (18%) Query: 10 LIGR-TPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 IGR TPL R +R+ + A I K E P S K + A++ G+ + + Sbjct: 71 SIGRPTPLFRAKRLEEYLKTPARIYFKYEGATPTGSHKINTAIPQAYFAKEEGI---EHV 127 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLE----RRMLLRAYGAELILTPGADGM 122 + E +G G A+A+ + + + M +S E RR +++ YGA + +P Sbjct: 128 VTETGAGQWGTAVALAASMYNMKSTIFMV-KVSYEQKPMRRSIMQLYGANVYASPTNLTE 186 Query: 123 SG----------------AIAKAEELA-KTDQRYFVPQQFENPANPAIHRVTTAEEVWRD 165 G A+++A E A K + RY V + +H+ +E Sbjct: 187 YGRKILETNPQHPGSLGIAMSEAIEYALKNEFRYLVGSVLDVVL---LHQSVIGQETITQ 243 Query: 166 TD---GKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPH---- 218 D DI++ VG G G K R++AV A P S G+ Sbjct: 244 LDLLGEDADILIGCVGGGSNFGGFTYPFIGNKKGKRYIAVSSAEIPKFSKGEYKYDFPDS 303 Query: 219 -------PIQGIGAGFVPP-----------------VLDQDLVDEIITVGNEDALNVARR 254 + +G +VPP +L ++ + E + A+ Sbjct: 304 AGLLPLVKMITLGKDYVPPPIYAGGLRYHGVAPTLSLLTKEGIVEWREYNEREIFEAAKI 363 Query: 255 LAREEGLLVGISSGAATVAALQVA--RRPENAGKLIVVVLPDFGERYLST 302 +G++ S A A + A R N K+IV L G LS Sbjct: 364 FIENQGIVPAPESAHAIRAVVDEAIEARKNNERKVIVFNLSGHGLLDLSN 413 >3IAU-A nrPDB Length = 366 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 62/296 (20%), Positives = 113/296 (38%), Gaps = 22/296 (7%) Query: 13 RTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTS 72 +PL +++D + K E S K R M+ + L D ++ ++ Sbjct: 60 ESPLELAEKLSDRLGVNFYIKREDKQRVFSFKLRGAYNMMSNLSREEL---DKGVITASA 116 Query: 73 GNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEEL 132 GN +A+ + MP T + +RA G +++L A A EL Sbjct: 117 GNHAQGVALAGQRLNCVAKIVMPTTTPQIKIDAVRALGGDVVLY--GKTFDEAQTHALEL 174 Query: 133 AKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIKE 192 ++ D ++P F++P + T E+ R + V VG GG I GVA K+ Sbjct: 175 SEKDGLKYIPP-FDDPG-VIKGQGTIGTEINRQLK-DIHAVFIPVGGGGLIAGVATFFKQ 231 Query: 193 RKPSARFVAVEPAASPVLSGGQKGPHPIQ---------GIGAGFVPPVL---DQDLVDEI 240 P+ + + VEP + ++ H ++ G+ V Q+L+D + Sbjct: 232 IAPNTKIIGVEPYGAASMTLSLHEGHRVKLSNVDTFADGVAVALVGEYTFAKCQELIDGM 291 Query: 241 ITVGNEDALNVARRLAREEGL-LVGISSGAATVAALQVARRPENAGKLIVVVLPDF 295 + V D ++ A + +EG ++ S A A + + IV + Sbjct: 292 VLVA-NDGISAAIKDVYDEGRNILETSGAVAIAGAAAYCEFYKIKNENIVAIASGA 346 >5KZM-B nrPDB Length = 396 Score = 164 bits (415), Expect = 5e-41, Method: Composition-based stats. Identities = 72/343 (20%), Positives = 131/343 (38%), Gaps = 52/343 (15%) Query: 7 ITQLIGR-TPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDT 65 + + GR T L + R + + K E + K + A++ G Sbjct: 48 LQEYAGRPTALTKTRNIVKNTRTKLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KKE 104 Query: 66 IILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRM----LLRAYGAELI-LTPGAD 120 II E +G G+A A+ CA +C + M +ER+ ++ GAE+I + G+ Sbjct: 105 IIAETGAGQHGVATALACALLDLKCRVYMGAK-DVERQSPNVFRMKLMGAEVIPVHSGSA 163 Query: 121 GMSGAIAKA--EELAKTDQRYFVPQQFENPAN-PAIHRV---TTAEEVWRDT----DGKV 170 + A +A + A + +++ P P I R EE + Sbjct: 164 TLKDACNEALRDWSANYSKAHYLLGTAAGPHPFPTIVREFQRMIGEETKQQMLAKEGRLP 223 Query: 171 DIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGP--HPIQGIGAGFV 228 D V+A VG G G+ + + + + + VEPA + +G P H GI G Sbjct: 224 DAVIACVGGGSNAIGMFADFID-EKNVKLIGVEPAGKGIETGEHGAPLKHGKTGIFFGMK 282 Query: 229 PPVLDQD-----------------------------LVDEIITVGNEDALNVARRLAREE 259 P++ + + +++AL+ + L ++E Sbjct: 283 APLMQNSDGQIEESYSISAGLDFPSVGPQHAHLLAIGRAKYASATDDEALDAFKLLCKKE 342 Query: 260 GLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLST 302 G++ + S A AL++A N +L+VV L G++ + T Sbjct: 343 GIIPALESSHALAHALKLAYEDPNKEQLLVVNLSGRGDKDIFT 385 >4NEG-A nrPDB Length = 400 Score = 160 bits (405), Expect = 8e-40, Method: Composition-based stats. Identities = 69/344 (20%), Positives = 125/344 (36%), Gaps = 54/344 (15%) Query: 5 EDITQLIGR-TPLVRLRRVTDGAV-ADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 62 + +GR TPL +T+ A I K E N + K + A A + Sbjct: 53 HYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKIN---NTIGQALLAVRMG 109 Query: 63 PDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRML----LRAYGAELI-LTP 117 ++ E +G G+A A VCA G CV+ M E + R+ L + GA++ + Sbjct: 110 KKKVVAETGAGQHGVATATVCALLGLECVIFMGE-EDVRRQKLNVFRMELLGAKVESVAA 168 Query: 118 GADGMSGAIAKAE--ELAKTDQRYFVPQQFENPAN-PAIHR---VTTAEEVWRD---TDG 168 G+ + A+ +A ++ +++ P P I R E + +G Sbjct: 169 GSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEG 228 Query: 169 KV-DIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGP---------- 217 K+ + VVA +G G G+ VE A V + Sbjct: 229 KLPEAVVACIGGGSNAMGMFYPF-VHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLH 287 Query: 218 --------------HPIQGIGAGFVPP-------VLDQDLVDEIITVGNEDALNVARRLA 256 I AG P +L ++ +++AL + L Sbjct: 288 GSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLT 347 Query: 257 REEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 300 ++EG++ + S A AL++A + + + +V+ L G++ + Sbjct: 348 KKEGIIPALESSHAVAYALKLAPQMK-EDEGLVICLSGRGDKDV 390 >1X1Q-A nrPDB Length = 418 Score = 157 bits (398), Expect = 5e-39, Method: Composition-based stats. Identities = 74/351 (21%), Positives = 132/351 (37%), Gaps = 58/351 (16%) Query: 5 EDITQLIGR-TPLVRLRRVTDG-AVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 62 + Q GR TPL +R+++ A + K E + K + A + G Sbjct: 68 HYLRQFAGRPTPLYHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALLARRMG--- 124 Query: 63 PDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRML----LRAYGAELI-LTP 117 +I E +G G+++A V A G CV+ M E + R+ L ++ GAE+ + Sbjct: 125 KRRVIAETGAGQHGVSVATVAALFGLECVVYMGE-EDVRRQALNVFRMKLLGAEVRPVAA 183 Query: 118 GADGMSGAIAKA--EELAKTDQRYFVPQQFENPA-NPAIHR---VTTAEEVWRD----TD 167 G+ + A +A + + +++ P P + R EEV R Sbjct: 184 GSRTLKDATNEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLELFG 243 Query: 168 GKVDIVVAGVGTGGTITGV---AQVIKERKPSARFVAVEPAASPVLSGGQKGP------- 217 D ++A VG G G+ + E +P + + VE A + +G Sbjct: 244 RLPDALIAAVGGGSNAIGLFAPFAYLPEGRP--KLIGVEAAGEGLSTGRHAASIGAGKRG 301 Query: 218 -----------------HPIQGIGAGFVPP-------VLDQDLVDEIITVGNEDALNVAR 253 P + AG P V E +V +E+AL + Sbjct: 302 VLHGSYMYLLYDHDGQITPAHSVSAGLDYPGVGPEHSYYADAGVAEYASVTDEEALEGFK 361 Query: 254 RLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPL 304 LAR EG++ + S A A +V + +++V+ L G++ ++ + Sbjct: 362 LLARLEGIIPALESAHAIAYAAKVVPEMD-KDQVVVINLSGRGDKDVTEVM 411 >1CX9-B nrPDB Length = 397 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 75/346 (21%), Positives = 128/346 (36%), Gaps = 52/346 (15%) Query: 4 AEDITQLIGR-TPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 62 A+ + GR T L + + +T G + K E + K + A++ G Sbjct: 46 ADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG--- 102 Query: 63 PDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRM----LLRAYGAELI-LTP 117 II E +G G+A A+ A G +C + M +ER+ +R GAE+I + Sbjct: 103 KSEIIAETGAGQHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHS 161 Query: 118 GADGMSGAIAKA--EELAKTDQRYFVPQQFENPA-NPAIHRV---TTAEE----VWRDTD 167 G+ + A +A + + +++ P P I R EE + Sbjct: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEG 221 Query: 168 GKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGP--HPIQGIGA 225 D V+A VG G G+ S + VEP + +G P H GI Sbjct: 222 RLPDAVIACVGGGSNAIGMFADFI-NDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280 Query: 226 GFVPP-----------------------------VLDQDLVDEIITVGNEDALNVARRLA 256 G P L+ + +++ +++AL + L Sbjct: 281 GMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLC 340 Query: 257 REEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLST 302 R EG++ + S A AL++ R +L+VV L G++ + T Sbjct: 341 RHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFT 386 >2ZSJ-A nrPDB Length = 352 Score = 147 bits (372), Expect = 5e-36, Method: Composition-based stats. Identities = 63/313 (20%), Positives = 109/313 (34%), Gaps = 31/313 (9%) Query: 12 GRTPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILE 69 G TPL+ + G I K E NP S KDR + A +AG ++ Sbjct: 29 GNTPLIEADNLARAIGFKGKIYLKYEGLNPTGSFKDRGMTLAISKAVEAG----KRAVIC 84 Query: 70 PTSGNTGIALAMVCAARGYRCVLTMPE-TMSLERRMLLRAYGAELILTPGADGMSGAIAK 128 ++GNT + A A G R + +P+ +++ + YGA+++ G A+ Sbjct: 85 ASTGNTSASAAAYAARAGLRAYVLLPKGAVAIGKLSQAMIYGAKVLAIQG--TFDDALNI 142 Query: 129 AEELAKTDQRYFVPQQFENPANPA--IHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGV 186 ++ + V N NP + T A E+ D VG G IT Sbjct: 143 VRKIGENFPVEIV-----NSVNPYRIEGQKTAAFEICDTLGEAPDYHFIPVGNAGNITAY 197 Query: 187 AQVIKERKPSARF------VAVEPAASPVLSGGQK--GPHPIQGIGAGFVPPVLD----- 233 + K + + + + + G P I P Sbjct: 198 WKGFKIYYEEGKITKLPRMMGWQAEGAAPIVKGYPIKNPQTIATAIKIGNPYSWKSALKA 257 Query: 234 -QDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVV-V 291 Q+ +I V + + L + +A EG+ +S A+ +++ R G +V Sbjct: 258 AQESGGKIDAVSDSEILYAYKLIASTEGVFCEPASAASVAGLIKLVREGFFKGGEVVTCT 317 Query: 292 LPDFGERYLSTPL 304 L G + T + Sbjct: 318 LTGNGLKDPDTAI 330 >5YBW-A nrPDB Length = 329 Score = 144 bits (364), Expect = 5e-35, Method: Composition-based stats. Identities = 58/280 (20%), Positives = 105/280 (37%), Gaps = 26/280 (9%) Query: 4 AEDITQLIGRTPLVRLRR----VTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAG 59 + I++ I TP+ V A K E S K R + + A + Sbjct: 15 YDRISKHILYTPVFTSPTFDRMVGSKAGRQFYFKAENLQKTGSFKARGALNAILCALERE 74 Query: 60 LIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA 119 ++ +SGN G ALA G +C + +P+T + + YGAE++ Sbjct: 75 PSLAG--VVTHSSGNHGQALAWASKRAGVKCCVVVPKTAPQVKFDAMENYGAEVVKCEPN 132 Query: 120 DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGT 179 E LAK+ ++ + + + T A E+ + +D ++ V Sbjct: 133 PTSR--KETCEGLAKSRGYKYISS--SDDYDVIAGQGTIALELLQQQP-DLDAILVSVSA 187 Query: 180 GGTITGVAQVIKERKPSARFVAVEPAASP---VLSGGQK-GPHPIQ---GIGAGFV---- 228 GG +G+ K K + VEP +S ++ P+P Q I G + Sbjct: 188 GGMASGICVYTKNTKSDLKVFLVEPEGKMLEECISKRERLWPNPPQFLDTIADGIILQQC 247 Query: 229 ----PPVLDQDLVDEIITVGNEDALNVARRLAREEGLLVG 264 P++ + E+ITV N++ + R + L++ Sbjct: 248 GNKTWPIILELPEKEVITVNNDNIVEAMRFVFARMKLVIE 287 >2D1F-A nrPDB Length = 360 Score = 143 bits (362), Expect = 8e-35, Method: Composition-based stats. Identities = 67/311 (21%), Positives = 108/311 (34%), Gaps = 28/311 (9%) Query: 12 GRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPT 71 G TPL+ ++ I K+E NP S KDR + A G +L + Sbjct: 37 GGTPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDALAHG----QRAVLCAS 92 Query: 72 SGNTGIALAMVCAARGYRCVLTMPE-TMSLERRMLLRAYGAELILTPGADGMSGAIAKAE 130 +GNT + A A G C + +P+ +++ + +GA++I G + A Sbjct: 93 TGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDG--NFDDCLELAR 150 Query: 131 ELAKTDQRYFVPQQFENPANP--AIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQ 188 ++A N NP + T A E+ D+ VG G IT + Sbjct: 151 KMAADFPT----ISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNITAYWK 206 Query: 189 VIKERK------PSARFVAVEPAASPVLSGGQKGPHP--IQGIGAGFVPPVL------DQ 234 E R + + A + L G+ HP I P Q Sbjct: 207 GYTEYHQLGLIDKLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASWTSAVEAQQ 266 Query: 235 DLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRP-ENAGKLIVVVLP 293 + +E+ L +AR EG+ V +S A+ L+ G +V + Sbjct: 267 QSKGRFLAASDEEILAAYHLVARVEGVFVEPASAASIAGLLKAIDDGWVARGSTVVCTVT 326 Query: 294 DFGERYLSTPL 304 G + T L Sbjct: 327 GNGLKDPDTAL 337 >1V71-A nrPDB Length = 323 Score = 138 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 63/302 (20%), Positives = 122/302 (40%), Gaps = 25/302 (8%) Query: 13 RTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTS 72 +TP++ V VA++ K E F + K R + L +A + +L +S Sbjct: 26 KTPVLTSSTVNKEFVAEVFFKCENFQKMGAFKFRGALNALSQLNEA---QRKAGVLTFSS 82 Query: 73 GNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEEL 132 GN A+A+ G + MP + + YG ++I+ A+E+ Sbjct: 83 GNHAQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQVIMYDRYK--DDREKMAKEI 140 Query: 133 AKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIKE 192 ++ + +P +++P + T A+E++ + G +D + +G GG ++G A + Sbjct: 141 SEREGLTIIPP-YDHPH-VLAGQGTAAKELFEEV-GPLDALFVCLGGGGLLSGSALAARH 197 Query: 193 RKPSARFVAVEPAASP-----VLSGGQKGPHPIQGIGAGFVPPVL-------DQDLVDEI 240 P+ VEP A G + I G L ++ VD+I Sbjct: 198 FAPNCEVYGVEPEAGNDGQQSFRKGSIVHIDTPKTIADGAQTQHLGNYTFSIIKEKVDDI 257 Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDF---GE 297 +TV +E+ ++ + A ++V + + AA A + + K I +++ E Sbjct: 258 LTVSDEELIDCLKFYAARMKIVVEPTGCLSFAAA--RAMKEKLKNKRIGIIISGGNVDIE 315 Query: 298 RY 299 RY Sbjct: 316 RY 317 >1UIN-A nrPDB Length = 351 Score = 133 bits (334), Expect = 1e-31, Method: Composition-based stats. Identities = 70/317 (22%), Positives = 113/317 (35%), Gaps = 31/317 (9%) Query: 7 ITQLIGRTPLVRLRRVTD--GAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPD 64 I+ L G TPL+ L+ + + AK E NP S KDR + A + G Sbjct: 22 ISLLEGSTPLIPLKGPEEARKKGIRLYAKYEGLNPTGSFKDRGMTLAVSKAVEGG----A 77 Query: 65 TIILEPTSGNTGIALAMVCAARGYRCVLTMPE-TMSLERRMLLRAYGAELILTPGADGMS 123 + ++GNT + A A G ++ +P ++L + +GA ++ G Sbjct: 78 QAVACASTGNTAASAAAYAARAGILAIVVLPAGYVALGKVAQSLVHGARIVQVEG--NFD 135 Query: 124 GAIAKAEELAKTDQRYFVPQQFENPANPA--IHRVTTAEEVWRDTDGKVDIVVAGVGTGG 181 A+ ++L + V N NP + T A EV + VG G Sbjct: 136 DALRLTQKLTEAFPVALV-----NSVNPHRLEGQKTLAFEVVDELGDAPHYHALPVGNAG 190 Query: 182 TITGVAQVIKERKPSA------RFVAVEPAASPVLSGGQK--GPHPIQGIGAGFVPPVLD 233 IT K R + + A + L G+ P + P Sbjct: 191 NITAHWMGYKAYHALGKAKRLPRMLGFQAAGAAPLVLGRPVERPETLATAIRIGNPASWQ 250 Query: 234 QDLVDE------IITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRP-ENAGK 286 + + I V +E+ L R LAREEG+ +S AA ++ R Sbjct: 251 GAVRAKEESGGVIEAVTDEEILFAYRYLAREEGIFCEPASAAAMAGVFKLLREGRLEPES 310 Query: 287 LIVVVLPDFGERYLSTP 303 +V+ L G + +T Sbjct: 311 TVVLTLTGHGLKDPATA 327 >2GN1-A nrPDB Length = 342 Score = 128 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 61/266 (22%), Positives = 109/266 (40%), Gaps = 20/266 (7%) Query: 11 IGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEP 70 I +T + R ++ +I K E S K R L + +A + ++ Sbjct: 38 IYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTEA---EKRKGVVAC 94 Query: 71 TSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAE 130 ++GN +++ CA G + MP+ + Y AE++L D + IAK Sbjct: 95 SAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLH--GDNFNDTIAKVS 152 Query: 131 ELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVI 190 E+ +T+ R F+P +++P + T E+ D VD V+ +G GG I G+A I Sbjct: 153 EIVETEGRIFIPP-YDDP-KVIAGQGTIGLEIMEDL-YDVDNVIVPIGGGGLIAGIAIAI 209 Query: 191 KERKPSARFVAVEPAA----SPVLSGGQKGPHPIQGIGAGF----VPPVLD----QDLVD 238 K P+ + + V+ + G+ H G A P L ++LVD Sbjct: 210 KSINPTIKVIGVQAENVHGMAASYYTGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVD 269 Query: 239 EIITVGNEDALNVARRLAREEGLLVG 264 +I+ V ++ N L + ++ Sbjct: 270 DIVLVSEDEIRNSMIALIQRNKVITE 295 >5CVC-A nrPDB Length = 346 Score = 117 bits (293), Expect = 7e-27, Method: Composition-based stats. Identities = 52/283 (18%), Positives = 97/283 (34%), Gaps = 25/283 (8%) Query: 7 ITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTI 66 I + RTP++ + + K E F A + K R + A + Sbjct: 30 IAPYVHRTPVMSSTSIDAMVGKKLFFKCECFQKAGAFKIRGASNSI-FALDDEQVSKG-- 86 Query: 67 ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAI 126 ++ +SGN A+A+ RG + +P + ++ YG +I + + + Sbjct: 87 VVTHSSGNHAAAVALAAKLRGIPAHIVIPRNAPASKVENVKCYGGHIIWSDASIESREYV 146 Query: 127 AKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGV 186 +K + + + N + T + E+ +D ++ + GG I+GV Sbjct: 147 SK--RVQEETGAVLIHP--INSKYTISGQGTVSLELLEQVPE-IDTIIVPISGGGLISGV 201 Query: 187 AQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQ-----GIGAGFVPPVLDQD------ 235 A K PS R +A EP + + + I I G + D Sbjct: 202 ALAAKAINPSIRILAAEPKGADDSAQSKAAGKIITLPSTNTIADGLRAFLGDLTWPVVRD 261 Query: 236 ---LVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAAL 275 V + DA+ + + + + V S AAL Sbjct: 262 LVDDVIVVDDTAIVDAMKMCYEILK---VAVEPSGAIGLAAAL 301 >6EQN-B nrPDB Length = 425 Score = 112 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 67/359 (18%), Positives = 129/359 (35%), Gaps = 67/359 (18%) Query: 11 IGR-TPLVRLRRVTDGAVADI--VAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTII 67 +GR TP++R +R+ + +I K+E + S K +A + A+ L + Sbjct: 72 VGRPTPIIRAKRLEEYLGNNIKIYLKMESYTYTGSHKINSALAHVYYAK---LDNAKFVT 128 Query: 68 LEPTSGNTGIALAMVCAARGYRCVLTMPET---MSLERRMLLRAYGAEL----------- 113 E +G G ++A+ A + + M T R+ +++ YGAE+ Sbjct: 129 TETGAGQWGSSVALASALFRMKAHIFMVRTSYYAKPYRKYMMQMYGAEVHPSPSDLTEFG 188 Query: 114 -------ILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDT 166 PG+ G+ AI+ A E A + +V N + + E + Sbjct: 189 RQLLAKDSNHPGSLGI--AISDAVEYAHKNGGKYVVGSVVNSD--IMFKTIAGMEAKKQM 244 Query: 167 ---DGKVDIVVAGVGTGGTITGVAQVI-----KERKPSARFVAVEPAASPVLSGG-QKGP 217 D ++ VG G +A + K +++A + P ++ G K Sbjct: 245 ELIGEDPDYIIGVVGGGSNYAALAYPFLGDELRSGKVRRKYIASGSSEVPKMTKGVYKYD 304 Query: 218 HP----------IQGIGAGFVPP-----------------VLDQDLVDEIITVGNEDALN 250 +P + IG+ FVPP +L + + E++ Sbjct: 305 YPDTAKLLPMLKMYTIGSDFVPPPVYAGGLRYHGVAPTLSLLISKGIVQARDYSQEESFK 364 Query: 251 VARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPLFADVA 309 A+ + EG + + A ++A + +G+ V++ G L +A V Sbjct: 365 WAKLFSELEGYIPAPETSHALPILAEIAEEAKKSGERKTVLVSFSGHGLLDLGNYASVL 423 >1VE5-A nrPDB Length = 311 Score = 111 bits (279), Expect = 3e-25, Method: Composition-based stats. Identities = 67/314 (21%), Positives = 112/314 (35%), Gaps = 30/314 (9%) Query: 4 AEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKP 63 I RTPL+ R + ++ K E S K R ++ +A ++ Sbjct: 11 FRRIAPYTHRTPLLTSRLLDGLLGKRLLLKAEHLQKTGSFKARGALS------KALALEN 64 Query: 64 DTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMS 123 +L +SGN +A G + ++ MPE S ++ RAYGAE++ Sbjct: 65 PKGLLAVSSGNHAQGVAYAAQVLGVKALVVMPEDASPYKKACARAYGAEVV--DRGVTAK 122 Query: 124 GAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGK---VDIVVAGVGTG 180 A L + Y + F++P + T E+ V+A VG G Sbjct: 123 NREEVARALQEETG-YALIHPFDDPL-VIAGQGTAGLELLAQAGRMGVFPGAVLAPVGGG 180 Query: 181 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPH-------------PIQGIGAGF 227 G + G+A +K P+ + VEP A+ + ++ + G Sbjct: 181 GLLAGLATAVKALSPTTLVLGVEPEAADDAKRSLEAGRILRLEAPPRTRADGVRTLSLGE 240 Query: 228 VPPVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKL 287 + ++ VD I+TV E L R L +V + A L+ R Sbjct: 241 RTFPILRERVDGILTVSEEALLEAERLLFTRTKQVVEPTGALPLAAVLEHGARLPQT--- 297 Query: 288 IVVVLPDFGERYLS 301 + +L G R S Sbjct: 298 -LALLLSGGNRDFS 310 >1PWH-A nrPDB Length = 327 Score = 103 bits (256), Expect = 1e-22, Method: Composition-based stats. Identities = 61/307 (19%), Positives = 115/307 (37%), Gaps = 31/307 (10%) Query: 13 RTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTS 72 +TPL ++ A + K++ P+ S K R + + + G + ++ Sbjct: 10 KTPLRDSMALSKVAGTSVFLKMDSSQPSGSFKIRGIGHLCKMKAKQGC----KHFVCSSA 65 Query: 73 GNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEEL 132 GN G+A A G + +P T L+ GA + + + + AI A+ L Sbjct: 66 GNAGMATAYAARRLGLPATIVVPSTTPALTIERLKNEGATVEVV--GEMLDEAIQLAKAL 123 Query: 133 AKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIKE 192 K + + F++P H + +E+ K +V VG GG + GV Q ++E Sbjct: 124 EKNNPGWVYISPFDDPLIWEGH-TSLVKELKETLSAKPGAIVLSVGGGGLLCGVVQGLRE 182 Query: 193 RK-PSARFVAVEPAA-----SPVLSGGQKGPHPIQ---------GIGAGFVPPVLDQDLV 237 +A+E + V G I +GA + + + Sbjct: 183 VGWEDVPIIAMETFGAHSFHAAVKEGKLVTLPKITSVAKALGVNTVGAQTLKLFYEHPIF 242 Query: 238 DEIITVGNEDALNVARRLAREEGLLVGISSGAATVAA-------LQVARRPENAGKLIVV 290 E+ + +++A+ + +E +LV + GAA A LQ R + +VV Sbjct: 243 SEV--ISDQEAVTAIEKFVDDEKILVEPACGAALAAVYSGVVCRLQAEARLQTPLASLVV 300 Query: 291 VLPDFGE 297 ++ Sbjct: 301 IVCGGSN 307 >5C3U-A nrPDB Length = 366 Score = 91.9 bits (227), Expect = 3e-19, Method: Composition-based stats. Identities = 63/318 (19%), Positives = 116/318 (36%), Gaps = 35/318 (11%) Query: 3 IAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 62 + +D+ L TPL+ +T ++ K+E P+ SVK R A A Q + Sbjct: 11 LFDDLQSLHVATPLLHAPNLTKELECNVFLKMENIQPSGSVKMRGIGAFCYQAVQ---TR 67 Query: 63 PDTIILEPTSG-NTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG 121 I SG NT +A++ G ++ +P+ + +R G+ LIL + Sbjct: 68 GTNIQFVCGSGPNTVLAVSYCARQLGVEAIIVVPKATNERICQSIRTDGSHLILY--GEN 125 Query: 122 MSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAG----- 176 + A A +L + + +VP ++ H T +E+ + + Sbjct: 126 WTAAEVHARKLVRRNGI-YVPSS-DHALIWQGH-STIVQELKTQLNDNPPAAIICPVGGG 182 Query: 177 VGTGGTITGVAQVIKERK-PSARFVAVEPAASP-----VLSGGQKGPHPIQGIGAGFV-- 228 G I G ++E +AVE S V++G I + Sbjct: 183 GLLNGVIMG----LQEADWKDVPVIAVETHGSNAFQASVVAGELVIMEKNNTIATSLISK 238 Query: 229 ---PPVLDQDLVDEIIT--VGNEDALNVARRLAREEGLLVGISSGAATV----AALQVAR 279 L+ L ++ V + A + R A + +LV S+GAA ++ Sbjct: 239 AVSSKSLELSLNHPVVPFAVSDAMAADAVRLFAEDFKMLVEASAGAALSLCYTHLIRDIL 298 Query: 280 RPENAGKLIVVVLPDFGE 297 + K +VV++ + Sbjct: 299 PSLSPAKDVVVLVTGGSD 316 >1E5X-A nrPDB Length = 486 Score = 86.9 bits (214), Expect = 9e-18, Method: Composition-based stats. Identities = 58/311 (18%), Positives = 108/311 (34%), Gaps = 41/311 (13%) Query: 12 GRTPLVRLRRVTDG--AVADIVAKLEFFNPANSVKDRIGVAMLQAAEQ-AGLIKPDTIIL 68 G + L R + D+ K + S KD ++ + + +P + Sbjct: 129 GNSNLFWAERFGKQFLGMNDLWVKHCGISHTGSFKDLGMTVLVSQVNRLRKMKRPVVGVG 188 Query: 69 EPTSGNTGIALAMVCAARGYRCVLTMP-ETMSLERRMLLRAYGAELILTPGADGMSGAIA 127 ++G+T AL+ CA+ G ++ +P +S+ + + A GA ++ G + Sbjct: 189 CASTGDTSAALSAYCASAGIPSIVFLPANKISMAQLVQPIANGAFVLSIDT--DFDGCMK 246 Query: 128 KAEELAKTDQRYFVPQQFENPANP--AIHRVTTAEEVWRDTDGKV-DIVVAGVGTGGTIT 184 E+ Y N N + T A E+ + D +V D V+ G G I Sbjct: 247 LIREITAELPIY-----LANSLNSLRLEGQKTAAIEILQQFDWQVPDWVIVPGGNLGNIY 301 Query: 185 GVAQVIK--------ERKPSARFVAVEPAASPVL-----SGGQK-----GPHPIQGIGAG 226 + K +R P R V + A + L SG + Sbjct: 302 AFYKGFKMCQELGLVDRIP--RMVCAQAANANPLYLHYKSGWKDFKPMTASTTFASAIQI 359 Query: 227 FVPPVLDQDLV-----DEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRP 281 P +D+ + + I+ E+ L A A G+ + +G A A ++ + Sbjct: 360 GDPVSIDRAVYALKKCNGIVEEATEEELMDAMAQADSTGMFICPHTGVALTALFKLRNQG 419 Query: 282 --ENAGKLIVV 290 + +VV Sbjct: 420 VIAPTDRTVVV 430 >4D9F-A nrPDB Length = 342 Score = 86.9 bits (214), Expect = 9e-18, Method: Composition-based stats. Identities = 58/311 (18%), Positives = 109/311 (35%), Gaps = 26/311 (8%) Query: 8 TQLIGR-TPLVRLRRVTDGAVADIVAKLEFFNP--ANSVKDRIGVAMLQAAEQAGLIKPD 64 + IG TPL L R++D +I K + P K R ++ A + G Sbjct: 26 LEFIGAPTPLEYLPRLSDYLGREIYIKRDDVTPIAMGGNKLRKLEFLVADALREG----A 81 Query: 65 TIILEPTS--GNTGIALAMVCAARGYRCVLTM--------PETMSLERRMLLRAYGAELI 114 ++ + N A V A G CV + ++ R+LL + ++ Sbjct: 82 DTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIE 141 Query: 115 LTPGADGMSGAI-AKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDG--KVD 171 + + A + R +V + A A+ V +A E+ + + + Sbjct: 142 MCDALTDPDAQLQTLATRIEAQGFRPYVIPVGGSSALGAMGYVESALEIAQQCEEVVGLS 201 Query: 172 IVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPV 231 VV G+ GT G+A ++ P + V + S + G + Sbjct: 202 SVVVASGSAGTHAGLAVGLEHLMPDVELIGVTVSRSVAEQKPKVIALQQAIAGQLALTAT 261 Query: 232 LDQDLVDEIIT----VGNEDALNVARRLAREEGLLVGIS-SGAATVAALQ-VARRPENAG 285 D L D+ V N+ + + LA EG+L+ +G A + ++++ N Sbjct: 262 ADIHLWDDYFAPGYGVPNDAGMEAVKLLASLEGVLLDPVYTGKAMAGLIDGISQKRFNDD 321 Query: 286 KLIVVVLPDFG 296 I+ + Sbjct: 322 GPILFIHTGGA 332 >5YGR-A nrPDB Length = 404 Score = 83.8 bits (206), Expect = 9e-17, Method: Composition-based stats. Identities = 77/361 (21%), Positives = 126/361 (34%), Gaps = 75/361 (20%) Query: 14 TPLVRLRRVTDGAV-ADIVAKLE----FFNP----ANSVK-------------DRIGVAM 51 TPL L ++ I K E N S + + A Sbjct: 46 TPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFKGLGGSYAVGKYLADKLQCDINSLSFAA 105 Query: 52 LQAAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGA 111 L E IK D + + T GN G +A G + V+ MP+ SL R +R +GA Sbjct: 106 LNTPEIKEKIK-DCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIRHHGA 164 Query: 112 ELILTPGADGMSGAIAKAEELAKTDQRYFVPQQ-------FENPANPAIHRVTTAEEVWR 164 E +T A+ A +A+T +V Q E P +T A E + Sbjct: 165 ECTITD--LNYDDAVRLAHRMAQTKG--WVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYE 220 Query: 165 DTDG----KVDIVV--AGVGT-GGTITGVA-QVIKERKPSARFVAVEPAASPVLSG---- 212 ++ AGVG+ G++ G + ++E P+ + VEP + L Sbjct: 221 QLAETNSPLPTHLILQAGVGSFAGSVMGYFVEKMQENIPN--IIVVEPHQANCLYQSAVM 278 Query: 213 GQKGPHPIQG----IGAGF---VPPVLDQDLVDE----IITVGNEDALNVARRLAR---- 257 PH + G I AG P ++ ++ + I+ + A R A Sbjct: 279 DDGQPHCVTGDMATIMAGLACGEPNIISWPIIRDNTSCFISADDCLAAKGMRISAAPRPG 338 Query: 258 EEGLLVGISSGAATVAAL----------QVARRPENAGKLIVVVLPDFGERYLSTPLFAD 307 + + SGA V L +A R + V+++ G+ S ++ D Sbjct: 339 TDTPFISGESGAIGVGLLYELMNNMHYQDLANRLQLDASAHVLLISTEGDT--SPDIYED 396 Query: 308 V 308 + Sbjct: 397 I 397 >1J0B-A nrPDB Length = 325 Score = 82.3 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 61/312 (19%), Positives = 117/312 (37%), Gaps = 32/312 (10%) Query: 13 RTPLVRLRRVTDGAVADIVAKLEFFNP--ANSVKDRIGVAMLQAAEQAGLIKPDTIILEP 70 TP+ L ++ AD+ K + K R +L A G +++ Sbjct: 21 ETPIQYLPNISREIGADVYIKRDDLTGLGIGGNKIRKLEYLLGDALSKG----ADVVITV 76 Query: 71 TS--GNTGIALAMVCAARGYRCVLTMPETMSLERRMLL-RAYGAELILTPGADG---MSG 124 + N + G +L + L+ LL + G E + D M Sbjct: 77 GAVHSNHAFVTGLAAKKLGLDAILVLRGKEELKGNYLLDKIMGIETRVYDAKDSFELMKY 136 Query: 125 AIAKAEELAKTDQR-YFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTI 183 A AEEL + ++ Y +P +P + E+ ++ K D +V G+GGT+ Sbjct: 137 AEEIAEELKREGRKPYVIPPGGASPIGTLGYVRAVG-EIATQSEVKFDSIVVAAGSGGTL 195 Query: 184 TGVAQVIKERKPSARFVAV------EPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLV 237 G++ + R V + E S + + ++ + G+ P + D Sbjct: 196 AGLSLGLSILNEDIRPVGIAVGRFGEVMTSKLDNLIKEAAELL-GVKVEVRPELYDYSF- 253 Query: 238 DEIITVGNEDALNVARRLAREEGLLVGIS-SGAATVAALQVARRPENAGKLIVVVLPD-- 294 E + E A + R++ EG+++ +G A + +AR+ E G+ I+ + Sbjct: 254 GEYGKITGEVA-QIIRKVGTREGIILDPVYTGKAFYGLVDLARKGEL-GEKILFIHTGGI 311 Query: 295 -----FGERYLS 301 +G++ LS Sbjct: 312 SGTFHYGDKLLS 323 >4H27-A nrPDB Length = 364 Score = 81.5 bits (200), Expect = 4e-16, Method: Composition-based stats. Identities = 56/307 (18%), Positives = 111/307 (36%), Gaps = 31/307 (10%) Query: 13 RTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTS 72 +TP+ ++ A + K++ P+ S K R + + G + +S Sbjct: 46 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGC----AHFVCSSS 101 Query: 73 GNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEEL 132 GN G+A A G + +P T L+ GA + + + + A A+ L Sbjct: 102 GNAGMAAAYAARQLGVPATIVVPGTTPALTIERLKNEGATVKVV--GELLDEAFELAKAL 159 Query: 133 AKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIKE 192 AK + + F++P H + +E+ K + VG GG + GV Q ++E Sbjct: 160 AKNNPGWVYIPPFDDPLIWEGH-ASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQE 218 Query: 193 RK-PSARFVAVEPAASPVLSGGQKGPH--------------PIQGIGAGFVPPVLDQDLV 237 +A+E + ++ +GA + + + Sbjct: 219 VGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIF 278 Query: 238 DEIITVGNEDALNVARRLAREEGLLVGISSGAATVAA-------LQVARRPENAGKLIVV 290 E+ + +++A+ + +E +LV + GAA A LQ+ +VV Sbjct: 279 SEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 336 Query: 291 VLPDFGE 297 ++ Sbjct: 337 IVCGGSN 343 >1RQX-A nrPDB Length = 338 Score = 80.4 bits (197), Expect = 9e-16, Method: Composition-based stats. Identities = 73/312 (23%), Positives = 112/312 (35%), Gaps = 37/312 (11%) Query: 10 LIGRTPLVRLRRVTDGAVADI--VAKLEFFNPA---NSVKDRIGVAMLQAAEQAGLIKPD 64 G TP+ L R++ + AK E N K R ++ A G D Sbjct: 12 TFGPTPIQPLARLSKHLGGKVHLYAKREDCNSGLAFGGNKTRKLEYLIPEALAQGC---D 68 Query: 65 TII-LEPTSGNTGIALAMVCAARGYRCVLTMPETMS--------LERRMLLRAYGAELIL 115 T++ + N +A V A G +CVL ++ + + R GA++ L Sbjct: 69 TLVSIGGIQSNQTRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIQMSRILGADVRL 128 Query: 116 TPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIH------RVTTAEEVWRD---T 166 P DG ++ E A R + + PA + H V AEEV Sbjct: 129 VP--DGFDIGFRRSWEDALESVRAAGGKPYAIPAGCSDHPLGGLGFVGFAEEVRAQEAEL 186 Query: 167 DGKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIG-A 225 K D VV TG T G+ + R + V+ +A P + Q Q Sbjct: 187 GFKFDYVVVCSVTGSTQAGMVVGFAADGRADRVIGVDASAKPAQTREQITRIARQTAEKV 246 Query: 226 GFVPPVLDQDLV-DEIIT-----VGNEDALNVARRLAREEGLLVGIS-SGAATVAALQVA 278 G ++ D+V DE + NE L R AR EG+L G + +++ Sbjct: 247 GLERDIMRADVVLDERFAGPEYGLPNEGTLEAIRLCARTEGMLTDPVYEGKSMHGMIEMV 306 Query: 279 RRPE-NAGKLIV 289 R E G ++ Sbjct: 307 RNGEFPEGSRVL 318 >2RKB-A nrPDB Length = 318 Score = 77.7 bits (190), Expect = 6e-15, Method: Composition-based stats. Identities = 73/304 (24%), Positives = 122/304 (40%), Gaps = 28/304 (9%) Query: 14 TPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSG 73 TPL+ ++ A + K E P+ S K R Q + G ++ + G Sbjct: 8 TPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMAKKGC----RHLVCSSGG 63 Query: 74 NTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEELA 133 N GIA A G + +PE+ SL+ L+ GAE+ LT A +A+ELA Sbjct: 64 NAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLT--GKVWDEANLRAQELA 121 Query: 134 KTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIKER 193 K D VP F++P H + +E+ +V VG GG + GV + E Sbjct: 122 KRDGWENVPP-FDHPLIWKGH-ASLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGLLEV 179 Query: 194 K-PSARFVAVEPAASPVLSGGQKGPHPI---------QGIGAGFVPPV-LDQDLVDEIIT 242 +A+E + + + + +GA V L+ V +I + Sbjct: 180 GWQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIHS 239 Query: 243 --VGNEDALNVARRLAREEGLLVGISSGAATVAALQ-VARRPENAG------KLIVVVLP 293 V + +A++ ++L +E +LV + GAA A + RR + G +VV++ Sbjct: 240 EVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSVVVIVC 299 Query: 294 DFGE 297 Sbjct: 300 GGNN 303 >4D9G-A nrPDB Length = 398 Score = 74.2 bits (181), Expect = 6e-14, Method: Composition-based stats. Identities = 59/307 (19%), Positives = 93/307 (30%), Gaps = 49/307 (15%) Query: 14 TPLVRLRRVTDGAVAD-IVAKLEFFNPA-NSVKDRIGVAMLQAA--EQ------------ 57 TPL L + + I+ K E N+ K G + E+ Sbjct: 45 TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSFEH 104 Query: 58 -AGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILT 116 I T GN G +A G V+ MP+ + ER + GAE I+T Sbjct: 105 LKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAECIVT 164 Query: 117 PGA------DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDG-- 168 M A E+ + + + P T A+E Sbjct: 165 DMNYDDTVRLTMQHAQQHGWEVVQ--DTAWEGYT-KIPTWIMQGYATLADEAVEQMREMG 221 Query: 169 -KVDIVVAGVGTGGTITGVAQVIKERKP--SARFVAVEPAASPVL-SGGQKGP-----HP 219 V+ G G GV + + + + VEP + + G KG Sbjct: 222 VTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIVNVGGD 281 Query: 220 IQGIGAGFV--------PPVLDQDLVDEIITVGNEDALNVARRLAREEG---LLVGISSG 268 + I AG +L ++ + I+ + A R L G ++ SG Sbjct: 282 MATIMAGLACGEPNPLGWEIL-RNCATQFISCQDSVAALGMRVLGNPYGNDPRIISGESG 340 Query: 269 AATVAAL 275 A + L Sbjct: 341 AVGLGVL 347 >3SS9-X nrPDB Length = 442 Score = 63.0 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 64/308 (20%), Positives = 116/308 (37%), Gaps = 55/308 (17%) Query: 24 DGAVADIVAKLEFFNP-ANSVKDRIGVAMLQA-----AEQAGLIKPDT------------ 65 ++ K + P + S+K R G+ + A A +AGL+ D Sbjct: 97 QPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQ 156 Query: 66 -----IILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGAD 120 I ++GN G+++ ++ A G++ + M ++ LR++G ++ Sbjct: 157 FFSQYSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDY 216 Query: 121 GMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEV---WRDTDGKVDI----- 172 G+ A+ + + A++D F EN + + + + VD Sbjct: 217 GV--AVEEGRKAAQSDPNCFFIDD-ENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLF 273 Query: 173 VVAGVGTGGTITGVAQVIK-ERKPSARFVAVEPAASPV-LSGGQKGPH---PIQGIG--- 224 V G GG GVA +K EP SP L G G H +Q IG Sbjct: 274 VYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDN 333 Query: 225 ------------AGFVPPVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATV 272 +GFV +++ L+D T+ ++ ++ LA+EEG+ + S+ A Sbjct: 334 LTAADGLAVGRASGFVGRAMER-LLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMA 392 Query: 273 AALQVARR 280 +V Sbjct: 393 GPQRVCAS 400 >3R0X-A nrPDB Length = 448 Score = 60.3 bits (145), Expect = 9e-10, Method: Composition-based stats. Identities = 62/291 (21%), Positives = 114/291 (39%), Gaps = 54/291 (18%) Query: 40 ANSVKDRIGVA-MLQAAEQ----AGLIKPDT-----------------IILEPTSGNTGI 77 + S+K R G+ +L AE+ AGL+ D I ++GN G+ Sbjct: 112 SGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGL 171 Query: 78 ALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEELAKTDQ 137 ++ ++ A G++ + M ++ LR++G ++ G+ A+ + + A++D Sbjct: 172 SIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGV--AVEQGRKAAQSDP 229 Query: 138 RYFVPQQFENPANPAIHRVTTAEEV---WRDTDGKVDI-----VVAGVGTGGTITGVAQV 189 F EN + + + + VD V G GG GVA Sbjct: 230 NCFFIDD-ENSRTLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFG 288 Query: 190 IK-ERKPSARFVAVEPAASPV-LSGGQKGPH---PIQGIG---------------AGFVP 229 +K + EP SP L G G H +Q IG +GFV Sbjct: 289 LKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTAADGLAVGRASGFVG 348 Query: 230 PVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARR 280 +++ L+D + T+ ++ ++ LA+EEG+ + S+ A ++ Sbjct: 349 RAMER-LLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICAS 398 >1J0D-A nrPDB Length = 341 Score = 59.9 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 50/286 (17%), Positives = 94/286 (32%), Gaps = 34/286 (11%) Query: 10 LIGRTPLVRLRRVTDGAVA--DIVAKLEFFNPA---NSVKDRIGVAMLQAAEQAGLIKPD 64 G +P+ L R++ + ++ AK E N R ++ + Sbjct: 12 TFGPSPISNLNRLSQHLGSKVNVYAKREDCNSGLAFGGNTLRKLEYIVPDIVEGDYTH-- 69 Query: 65 TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSL-----------ERRMLLRAYGAEL 113 + + N +A + A G +CVL + + + L R GA++ Sbjct: 70 LVSIGGRQSNQTRMVAALAAKLGKKCVLIQEDWVPIPEAEKDVYNRVGNIELSRIMGADV 129 Query: 114 ILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTT------AEEVWRD-- 165 + + + A L + + P + PA + H+ A+EV Sbjct: 130 RVIEDGFDIGMRKSFANALQELEDAGHKP--YPIPAGCSEHKYGGLGFVGFADEVINQEV 187 Query: 166 -TDGKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQK-----GPHP 219 K D +V TG T G+ + + +A++ + + + Q Sbjct: 188 ELGIKFDKIVVCCVTGSTTAGILAGMAQYGRQDDVIAIDASFTSEKTKEQTLRIANNTAK 247 Query: 220 IQGIGAGFVPPVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGI 265 + G+ F LD V NE + R A +EG+L Sbjct: 248 LIGVEHEFKDFTLDTRFAYPCYGVPNEGTIEAIRTCAEQEGVLTDP 293 >2VCY-A nrPDB Length = 344 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 39/88 (44%), Gaps = 13/88 (14%) Query: 36 FFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMV--CAARGYRCVLT 93 NP ML EQ ++P +++ S N+G+ A++ AA G R + Sbjct: 136 GVNPC------TAYRMLMDFEQ---LQPGDSVIQNAS-NSGVGQAVIQIAAALGLRTINV 185 Query: 94 MPETMSLERR-MLLRAYGAELILTPGAD 120 + + +++ L++ GAE ++T Sbjct: 186 VRDRPDIQKLSDRLKSLGAEHVITEEEL 213 >1VB3-A nrPDB Length = 428 Score = 37.6 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 58/292 (19%), Positives = 86/292 (29%), Gaps = 40/292 (13%) Query: 34 LEFFN-PANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMV-CAARGYRCV 91 LE F+ P + KD G M Q KP IL TSG+TG A+A + V Sbjct: 96 LELFHGPTLAFKDFGGRFMAQMLTHIAGDKP-VTILTATSGDTGAAVAHAFYGLPNVKVV 154 Query: 92 LTMP-ETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPAN 150 + P +S + L G + A ++ ++ N AN Sbjct: 155 ILYPRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALG--LNSAN 212 Query: 151 PAIHRVTTAE-----EVWRDTDGKV-DIVVAGVGTGGTITGVAQVIKERK---PSARFVA 201 A+ E + + +V V G + + + P RF+A Sbjct: 213 SINISRLLAQICYYFEAVAQLPQETRNQLVVSV-PSGNFGDLTAGLLAKSLGLPVKRFIA 271 Query: 202 VEPAASPV---LSGGQKGPHPIQ----------------GIGAGFVPPVLDQDLVDEIIT 242 V L GQ P Q + F + + Sbjct: 272 ATNVNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELG-YAA 330 Query: 243 VGNEDALNVARRLAREEGLLVGISSGAATVA-ALQVARRPENAGKLIVVVLP 293 V +E R L +E G AA AL+ P G + P Sbjct: 331 VDDETTQQTMREL-KELGYTSEPH--AAVAYRALRDQLNPGEYGLFLGTAHP 379 >3IP1-A nrPDB Length = 404 Score = 35.7 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 2/70 (2%) Query: 57 QAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILT 116 + G I+P ++ G I LA V + + S RR L + GA+ ++ Sbjct: 207 RGGGIRPGDNVVILGGG--PIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVID 264 Query: 117 PGADGMSGAI 126 P + A+ Sbjct: 265 PTKENFVEAV 274 >4E77-A nrPDB Length = 429 Score = 35.7 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 46/252 (18%), Positives = 77/252 (30%), Gaps = 31/252 (12%) Query: 49 VAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRA 108 +A ++ A + + II+EP +GN C+ +PE + R L Sbjct: 187 LASVRQAFEQYPQEVACIIVEPVAGN-------------MNCIPPLPEFLPGLR-ALCDE 232 Query: 109 YGAELILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDG 168 +GA LI+ G A+A A++ + P + EV Sbjct: 233 FGALLIIDEVMTGFRVALAGAQDYYHVIPDLTCLGKIIGGGMP-VGAFGGRREVMNAL-- 289 Query: 169 KVDIVVAGVGT-GGTITGVAQVI--KERKPSARFVAVEPAASPVLSGGQKGPHPIQGI-- 223 V GT G +A + L+ G + + I Sbjct: 290 APTGPVYQAGTLSGNPIAMAAGFACLTEISQVGVYETLTELTDSLATGLRHAAKEENIPL 349 Query: 224 -----GAGFVPPVLDQDLVDEIITVG--NEDALNVARRLAREEGLLVGISSGAATVAALQ 276 G F + D V V + + L EEG+ + S A + Sbjct: 350 VVNHVGGMFGLFFTNADTVTCYQDVMNCDVERFKRFFHLMLEEGVYLAPS--AFEAGFMS 407 Query: 277 VARRPENAGKLI 288 +A E+ K + Sbjct: 408 LAHSNEDIQKTV 419 >5OC1-A nrPDB Length = 565 Score = 34.9 bits (79), Expect = 0.040, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 45/129 (34%), Gaps = 15/129 (11%) Query: 171 DIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPP 230 D VV G G G + VA + E P + +E S G + P + G VP Sbjct: 3 DYVVVGAGNAGNV--VAARLTE-DPDVSVLVLEAGVSDENVLGAEAPL----LAPGLVP- 54 Query: 231 VLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVV 290 + + + A R +A G ++G SS + + + E+ Sbjct: 55 ----NSIFDWNYTTTAQAGYNGRSIAYPRGRMLGGSS--SVHYMVMMRGSTEDFD-RYAA 107 Query: 291 VLPDFGERY 299 V D G + Sbjct: 108 VTGDEGWNW 116 >4EI8-A nrPDB Length = 389 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 28/141 (19%), Positives = 54/141 (38%), Gaps = 6/141 (4%) Query: 111 AELILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKV 170 A++I TPG ++ K+ +L + ++ Q N + T EE+ + Sbjct: 240 AQVINTPGVLSLAKLELKSNQLDTENPLGYL-TQLGNALEKGVLYDTEREELESAKKSAL 298 Query: 171 DIVVAGVGTG-----GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGA 225 IV + + G + + +KER P + P + + ++ + A Sbjct: 299 SIVTSPLRAGRLYNFSFLNQMENFLKERTPYVDERPIAPYVNKHTTKKEEDIVKFYSVVA 358 Query: 226 GFVPPVLDQDLVDEIITVGNE 246 G P D++DEI + E Sbjct: 359 GLPLPKRVSDIIDEITRIKEE 379 >2UUU-A nrPDB Length = 584 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 43/146 (29%), Gaps = 28/146 (19%) Query: 111 AELILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKV 170 A + T G + I K V P H E K Sbjct: 113 ARITHTFG-KSLRDLIRVRIGQVKNAPDLIVL--------PHSHEEV---ERLVQLAHKY 160 Query: 171 DIVVAGVGTGGTITGVAQVI--------KERKPSARFVAVEPAA-SPVLSGGQKGP---- 217 ++V+ +G G I G + + + + + + V+ + + G GP Sbjct: 161 NVVIIPMGGGSNIVGAIEPVSNERFTVSIDMRRMNKVLWVDRREMTACIQVGIMGPELEK 220 Query: 218 --HPIQGIGAGFVPPVLDQDLVDEII 241 H QG+ G P + + + Sbjct: 221 QLHK-QGVSLGHDPDSFEFSTLGGWL 245 >3AOE-E nrPDB Length = 419 Score = 32.6 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 21/60 (35%), Gaps = 3/60 (5%) Query: 55 AEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLT---MPETMSLERRMLLRAYGA 111 A++ GL ++ G G A+A+ G R V M + E + A Sbjct: 209 AKRRGLDLRGARVVVQGLGQVGAAVALHAERLGMRVVAVATSMGGMYAPEGLDVAEVLSA 268 >1G3N-B nrPDB Length = 168 Score = 32.6 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 4/58 (6%) Query: 12 GRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILE 69 GRT L ++ ++ + NP +KDR G A++ A +AG + +LE Sbjct: 38 GRTALQVMKLGNPEIARRLLLR--GANP--DLKDRTGFAVIHDAARAGFLDTLQTLLE 91 >2UUQ-A nrPDB Length = 414 Score = 32.2 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 46/126 (36%), Gaps = 17/126 (13%) Query: 95 PETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEELAKTDQRYFVPQQFEN-PANPAI 153 P + R+++ R + + T + + E+L V + F+ P+ Sbjct: 101 PPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVA 160 Query: 154 HRVTTAEEVWRDTDGKVDIVVA-----GVGTG-----GTITGVAQVIKERKPSARFVAVE 203 H + EE W DG +VA G TG G++ + ER+ + E Sbjct: 161 HYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFTGLIERRRT------E 214 Query: 204 PAASPV 209 PA + Sbjct: 215 PADDAI 220 >4RVS-A nrPDB Length = 329 Score = 31.4 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 31/72 (43%), Gaps = 4/72 (5%) Query: 62 KPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG 121 + DT+++ +G G+ L G R + T+ E+ L + GA+++L D Sbjct: 142 RGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTA---EKAKLSKDAGADVVLDYPEDA 198 Query: 122 MSGAIAKAEELA 133 A + EL Sbjct: 199 WQFA-GRVRELT 209 >1R18-A nrPDB Length = 227 Score = 31.1 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 47/210 (22%), Positives = 77/210 (36%), Gaps = 32/210 (15%) Query: 107 RAYGAE---LILTPGADGMSGAIAKAEELAKTDQRYFVP-QQFENPANP--------AIH 154 R+ GA LI G+ + A A+ + +TD++++ P + + P A H Sbjct: 10 RSVGANNEDLIRQLKDHGVIASDAVAQAMKETDRKHYSPRNPYMDAPQPIGGGVTISAPH 69 Query: 155 RVTTAEEVWRD-TDGKVDIVVAGVGTGGTITGVAQVIKER--KPSARFVAVEPAASPVLS 211 A E RD I+ G G+G + IK + R V +E A V Sbjct: 70 MHAFALEYLRDHLKPGARILDVGSGSGYLTACFYRYIKAKGVDADTRIVGIEHQAELVRR 129 Query: 212 GGQKGPHPIQGIGAGFVPPVLDQDLVD-EIITVGNEDALNVARRLAREEGLLVGISSGAA 270 A D+ ++D + + D A + VG AA Sbjct: 130 SK-----------ANLNTD--DRSMLDSGQLLIVEGDGRKGYPPNAPYNAIHVG---AAA 173 Query: 271 TVAALQVARRPENAGKLIVVVLPDFGERYL 300 ++ + + G+LIV V PD G +Y+ Sbjct: 174 PDTPTELINQLASGGRLIVPVGPDGGSQYM 203 >4J6F-A nrPDB Length = 382 Score = 30.7 bits (68), Expect = 0.79, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 7/82 (8%) Query: 48 GVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLR 107 G ML+ A L +T+++ SG G A+ + ARG + + + Sbjct: 195 GERMLERAR---LAAGETVLVTGASGGVGSAIIQLARARGAVPIAV----AGPGKEAAML 247 Query: 108 AYGAELILTPGADGMSGAIAKA 129 GA+ ++T G ++ A+ A Sbjct: 248 DIGAQAVVTRGQGDLAEAVEAA 269 >5Y2D-A nrPDB Length = 465 Score = 30.7 bits (68), Expect = 0.82, Method: Composition-based stats. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 7/43 (16%) Query: 38 NPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALA 80 NP NS G A++ + GL+ +T I+ T GN GI A Sbjct: 207 NPGNS-----GGALID--SRGGLVGINTAIISKTGGNHGIGFA 242 >1PL8-A nrPDB Length = 356 Score = 30.3 bits (67), Expect = 1.00, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 29/77 (37%), Gaps = 2/77 (2%) Query: 54 AAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAEL 113 A + G + +L +G G+ +V A G V+ +S R + GA+L Sbjct: 162 HACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVV--TDLSATRLSKAKEIGADL 219 Query: 114 ILTPGADGMSGAIAKAE 130 +L + K E Sbjct: 220 VLQISKESPQEIARKVE 236 >5Y28-A nrPDB Length = 357 Score = 30.3 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 7/43 (16%) Query: 38 NPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALA 80 NP NS G A++ + GL+ +T I+ T GN GI A Sbjct: 207 NPGNS-----GGALID--SRGGLVGINTAIISKTGGNHGIGFA 242 >1DEL-A nrPDB Length = 241 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 17/45 (37%), Gaps = 3/45 (6%) Query: 87 GYRCVLTMPETMSLERRMLLRAYGAELILT--PGADGMSGAIAKA 129 GY + P+T RA GA +I PG I +A Sbjct: 167 GYDYYIV-PDTRQDHEMDAARAMGATVIHVVRPGQKSNDTHITEA 210 >1ZYK-A nrPDB Length = 345 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 50/144 (34%), Gaps = 15/144 (10%) Query: 104 MLLRAYGAELILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPA--NPAIHRVTTAEE 161 +L A G +I+ P +A+EL F+ Q+ +PA N A R T Sbjct: 120 DVLEALGYNIIVPP---------ERAKELVNKTNFVFLFAQYYHPAMKNVANVRKTLGIR 170 Query: 162 VWRDTDGKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQ 221 + G + + GV S ++ +L G+ G + Sbjct: 171 TIFNILGPLT---NPANAKYQLMGVFSKDHLDLLSKSAYELD-FNKIILVYGEPGIDEVS 226 Query: 222 GIGAGFVPPVLDQDLVDEIITVGN 245 IG F+ V + + + + V + Sbjct: 227 PIGNTFMKIVSKRGIEEVKLNVTD 250 >2Y4O-A nrPDB Length = 443 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 22/48 (45%) Query: 242 TVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIV 289 +V + + +AR L +VG+SSG +AA + + ++ Sbjct: 390 SVTDGERAALARELQHRIKTMVGVSSGVTVLAAGGIPATATGKARRVI 437 >3N0G-A nrPDB Length = 555 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 30/77 (38%), Gaps = 4/77 (5%) Query: 96 ETMSLERRMLLRAYGAELILTPGADGMSGA----IAKAEELAKTDQRYFVPQQFENPANP 151 E + + + +L Y A + G + + A I+ +EL++ + +Q + Sbjct: 142 ENLKEDTKAILSLYEASFLALEGENILDEARVFAISHLKELSEEKIGKELAEQVNHALEL 201 Query: 152 AIHRVTTAEEVWRDTDG 168 +HR T E + Sbjct: 202 PLHRRTQRLEAVWSIEA 218 >5G2R-A nrPDB Length = 471 Score = 29.5 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 39/105 (37%), Gaps = 14/105 (13%) Query: 60 LIKPDTIILEPTSGNTGIA-------LAMVCAARGYRCVLTMPETMSLERRMLLRAY--- 109 ++ ++EPT+G G +V A +C + + +R+ L + Sbjct: 200 ILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEA 259 Query: 110 ---GAELILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANP 151 G ++ILT G M G + L + + + + P P Sbjct: 260 VSSGVDIILTSGGVSM-GDRDFVKPLLEEKGKVYFSKVLMKPGKP 303 >2AN1-A nrPDB Length = 292 Score = 29.5 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 24/83 (28%), Gaps = 7/83 (8%) Query: 115 LTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVV 174 P A + + L V QQ + T E+ + D + Sbjct: 15 RHPTALTTHEMLYR--WLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQAD-----LA 67 Query: 175 AGVGTGGTITGVAQVIKERKPSA 197 VG G + G A+ + + Sbjct: 68 VVVGGDGNMLGAARTLARYDINV 90 >3J9R-A nrPDB Length = 386 Score = 29.1 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 31/89 (34%), Gaps = 4/89 (4%) Query: 46 RIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTM--PETMSLERR 103 R G+ L + +P ++ S +A AM A R + + P + Sbjct: 108 RTGLQALLDGKSRFNAQPRLLVAPGHSAQQAVATAMDGLAEKLRAIAILDGPNSTDEAAV 167 Query: 104 MLLRAYGAE--LILTPGADGMSGAIAKAE 130 + +G++ ++ PG A A Sbjct: 168 AYAKNFGSKRLFMVDPGVQVWDSATNAAR 196 >3CJR-A nrPDB Length = 254 Score = 29.1 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 24/57 (42%) Query: 201 AVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGNEDALNVARRLAR 257 A++P + GG +G +G F P +D VG+ED L RR + Sbjct: 12 ALDPILPGLFDGGARGLWEREGEVWAFFPAPVDLPYEGVWEEVGDEDWLEAWRRDLK 68 >4HAO-A nrPDB Length = 304 Score = 29.1 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 25/72 (34%), Gaps = 7/72 (9%) Query: 131 ELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVI 190 L V QQ + N + T D K D+ V VG G + G A+V+ Sbjct: 30 WLKARGYAVMVEQQIAHDLN--LTDAITGS--LADIGQKADLAVV-VGGDGNMLGAARVL 84 Query: 191 KERKPSARFVAV 202 + + V Sbjct: 85 ARYD--IKVIGV 94 >1IHO-A nrPDB Length = 283 Score = 28.7 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 8/89 (8%) Query: 96 ETMSLERRML--LRAYGAELILTPGADGM-SGAIAKAEELAKTDQRYFV-----PQQFEN 147 ET+ L R+ + LR G + L P + G + +E V P QF+ Sbjct: 5 ETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADVVVVSIFVNPMQFDR 64 Query: 148 PANPAIHRVTTAEEVWRDTDGKVDIVVAG 176 P + A + T E+ + KVD+V A Sbjct: 65 PEDLARYPRTLQEDCEKLNKRKVDLVFAP 93 >3FBG-A nrPDB Length = 346 Score = 28.7 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 40/116 (34%), Gaps = 8/116 (6%) Query: 58 AGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTP 117 + T+++ +G G + A G R + T ++E + GA+++L Sbjct: 146 RNENEGKTLLIINGAGGVGSIATQIAKAYGLRVITTASRNETIEWTKKM---GADIVLNH 202 Query: 118 GADGMSGAIAKAEELAKTDQRYFVPQQFENPA----NPAIHRVTT-AEEVWRDTDG 168 ++ + EL F + + P H T A E +D + Sbjct: 203 KESLLNQFKTQGIELVDYVFCTFNTDMYYDDMIQLVKPRGHIATIVAFENDQDLNA 258 >3KIZ-A nrPDB Length = 394 Score = 28.4 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 13/32 (40%) Query: 151 PAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGT 182 P +E+ GK+D VV G G T Sbjct: 264 PTRTYAPLMKEIIHQYKGKLDGVVHCSGGGQT 295 >3GUZ-A nrPDB Length = 176 Score = 28.4 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 8/89 (8%) Query: 96 ETMSLERRML--LRAYGAELILTPGADGM-SGAI-----AKAEELAKTDQRYFVPQQFEN 147 ET+ L R+ + LR G + L P + G + AKA + P QF+ Sbjct: 5 ETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADVVAVSIFVNPMQFDR 64 Query: 148 PANPAIHRVTTAEEVWRDTDGKVDIVVAG 176 P + A + T E+ + KVD+V A Sbjct: 65 PEDLARYPRTLQEDCEKLNKRKVDLVFAP 93 >2VPQ-A nrPDB Length = 451 Score = 28.0 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 23/47 (48%) Query: 96 ETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEELAKTDQRYFVP 142 + M ++ A + + PG+DG+ +++A+++AK + Sbjct: 110 QKMGIKDVAKAEMIKANVPVVPGSDGLMKDVSEAKKIAKKIGYPVII 156 >3GFB-A nrPDB Length = 350 Score = 28.0 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 5/61 (8%) Query: 58 AGLIKPDTIILEPTSGNTGI-ALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILT 116 AG I + ++ +G G+ +A+ A+ Y +++ P S RR L + GA+ ++ Sbjct: 163 AGPIAGRSTLI-TGAGPLGLLGIAVAKASGAYPVIVSEP---SEFRRKLAKKVGADYVVN 218 Query: 117 P 117 P Sbjct: 219 P 219 >5YLN-A nrPDB Length = 356 Score = 28.0 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 33/102 (32%), Gaps = 4/102 (3%) Query: 58 AGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTP 117 G ++P + SG G+A A++ A L M + + R ++GA Sbjct: 166 KGKVEPGCSVAIIGSGPVGLA-ALLTAQFYSPAKLIMVD-LDDNRLETALSFGAT--HKV 221 Query: 118 GADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTA 159 + AI + +L + PA + Sbjct: 222 NSSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIG 263 >1GPJ-A nrPDB Length = 404 Score = 28.0 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 5/73 (6%) Query: 47 IGVAMLQAAEQA-GLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLER-RM 104 IG A ++ AE+ G + T+++ +G G +A RG R VL + ER Sbjct: 150 IGSAAVELAERELGSLHDKTVLV-VGAGEMGKTVAKSLVDRGVRAVLV--ANRTYERAVE 206 Query: 105 LLRAYGAELILTP 117 L R G E + Sbjct: 207 LARDLGGEAVRFD 219 >3DM5-A nrPDB Length = 443 Score = 28.0 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 24/164 (14%), Positives = 51/164 (31%), Gaps = 14/164 (8%) Query: 97 TMSLERRMLLRAYGAELILTPGA---DGMSGAIAKAEELAKTDQRYFVPQQFENPANPAI 153 ++ E ++ G ++I+ A I + ++++ + V + Sbjct: 169 KLAKEGVDYFKSKGVDIIIVDTAGRHKEDKALIEEMKQISNVIHPHEVILVIDGTIGQQA 228 Query: 154 HRVTTAEE----VWRDTDGKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPV 209 + A + + K+D G G + IK + +EP P Sbjct: 229 YNQALAFKEATPIGSIIVTKLDGSAKGGGALSAVAATGAPIKFIGTGEKIDDIEPFDPPR 288 Query: 210 LSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGNEDALNVAR 253 G IQG+ F +++ + + ED R Sbjct: 289 FVSRLLGLGDIQGLLEKF-------KELEKEVEIKEEDIERFLR 325 >1U6I-A nrPDB Length = 283 Score = 27.6 bits (60), Expect = 6.5, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 56/150 (37%), Gaps = 29/150 (19%) Query: 23 TDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMV 82 +++A E+ PA + D G+ + E+ GL I+++P Sbjct: 79 GPSKAREMLADSEY--PAVIIGDAPGLKVKDEMEEQGL---GYILVKPD----------- 122 Query: 83 CAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAE--ELAKTDQRYF 140 A G R P M++ L++ A + + I KA+ E+++ D Sbjct: 123 -AMLGARREFLDPVEMAIYNADLMKVLAATGVFRVVQEAFDELIEKAKEDEISENDLPKL 181 Query: 141 VPQ--------QFENPANPAIHRVTTAEEV 162 V +FENP A+ + A E+ Sbjct: 182 VIDRNTLLEREEFENPY--AMVKAMAALEI 209 >6ETZ-A nrPDB Length = 989 Score = 27.6 bits (60), Expect = 7.8, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 25/64 (39%), Gaps = 5/64 (7%) Query: 177 VGTGGTITGVAQVIKERKPSARFVAVEPAAS----PVLSGGQKGPHPIQGIGAGFVPPVL 232 GTG + +++ K+R PS R + E S V S IG G P + Sbjct: 421 AGTGRNLAAMSRWTKDRDPS-RPIHYEGDWSSEHVDVYSRMYASQAETALIGQGIEPALN 479 Query: 233 DQDL 236 D L Sbjct: 480 DAAL 483 >2DR1-A nrPDB Length = 386 Score = 27.2 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 2/59 (3%) Query: 241 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERY 299 + + + L + + E LLV SSG + A + GK++V ++ FG+RY Sbjct: 54 VHMDTVERLREFLEVEKGEVLLV-PSSGTGIMEA-SIRNGVSKGGKVLVTIIGAFGKRY 110 >1E3W-A nrPDB Length = 261 Score = 27.2 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 21/68 (30%) Query: 71 TSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAE 130 T G +G+ L+ G + + + E + G I P + A Sbjct: 16 TGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAAL 75 Query: 131 ELAKTDQR 138 LAK Sbjct: 76 TLAKEKFG 83 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.147 0.396 Lambda K H 0.267 0.0447 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,548,157 Number of Sequences: 36641 Number of extensions: 526645 Number of successful extensions: 2424 Number of sequences better than 10.0: 139 Number of HSP's better than 10.0 without gapping: 136 Number of HSP's successfully gapped in prelim test: 85 Number of HSP's that attempted gapping in prelim test: 1958 Number of HSP's gapped (non-prelim): 237 length of query: 310 length of database: 10,336,785 effective HSP length: 97 effective length of query: 213 effective length of database: 6,782,608 effective search space: 1444695504 effective search space used: 1444695504 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.2 bits)