BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P9WHH9 (464 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3II4-A nrPDB 943 0.0 1EBD-A nrPDB 300 1e-81 3URH-A nrPDB 295 3e-80 2YQU-A nrPDB 286 1e-77 6AON-A nrPDB 280 7e-76 5TR3-A nrPDB 278 5e-75 5U8W-A nrPDB 277 8e-75 3LAD-A nrPDB 275 2e-74 5J5Z-A nrPDB 275 4e-74 1DXL-A nrPDB 273 1e-73 2QAE-A nrPDB 271 3e-73 1V59-A nrPDB 271 6e-73 2EQ6-A nrPDB 259 1e-69 4JDR-A nrPDB 254 7e-68 6CMZ-A nrPDB 251 5e-67 1LVL-A nrPDB 241 3e-64 6BZ0-A nrPDB 239 2e-63 5X1Y-B nrPDB 210 9e-55 5U25-A nrPDB 196 2e-50 4YWO-A nrPDB 194 9e-50 1OJT-A nrPDB 191 7e-49 2R9Z-A nrPDB 174 6e-44 1ZK7-A nrPDB 172 2e-43 3O0H-A nrPDB 172 3e-43 6DU7-A nrPDB 172 4e-43 4DNA-A nrPDB 167 9e-42 6N7F-A nrPDB 160 2e-39 6B4O-A nrPDB 157 8e-39 2YAU-A nrPDB 151 5e-37 1GEU-A nrPDB 150 9e-37 3L8K-A nrPDB 149 3e-36 2WOV-A nrPDB 147 8e-36 1XDI-A nrPDB 145 4e-35 5VDN-A nrPDB 142 3e-34 5V36-A nrPDB 140 8e-34 2HQM-A nrPDB 140 1e-33 2AAQ-A nrPDB 139 3e-33 4NEW-A nrPDB 137 8e-33 1FEC-A nrPDB 135 3e-32 5U1O-A nrPDB 132 5e-31 3IC9-A nrPDB 129 2e-30 2NVK-X nrPDB 120 9e-28 1ZDL-A nrPDB 119 2e-27 1ONF-A nrPDB 115 4e-26 4KPR-E nrPDB 113 2e-25 5W1J-A nrPDB 102 3e-22 2CFY-A nrPDB 102 3e-22 2X8H-A nrPDB 99 6e-21 4LA1-A nrPDB 97 2e-20 4B1B-A nrPDB 96 2e-20 5ER0-A nrPDB 82 6e-16 3Q6J-A nrPDB 79 3e-15 4FX9-A nrPDB 66 3e-11 2BC1-A nrPDB 65 5e-11 2CDU-A nrPDB 65 5e-11 3CGD-A nrPDB 65 6e-11 3ICS-A nrPDB 64 1e-10 3IWA-A nrPDB 64 1e-10 3FG2-P nrPDB 63 2e-10 3LXD-A nrPDB 62 4e-10 4GCM-A nrPDB 53 2e-07 2Q7V-A nrPDB 53 3e-07 2YVG-A nrPDB 52 7e-07 5MIU-A nrPDB 52 8e-07 1NHQ-A nrPDB 51 9e-07 1Q1R-A nrPDB 50 2e-06 3NTA-A nrPDB 49 4e-06 5JCN-A nrPDB 49 4e-06 1YQZ-A nrPDB 48 9e-06 5MJK-A nrPDB 47 2e-05 5KVH-A nrPDB 46 3e-05 4EMJ-A nrPDB 46 3e-05 5UTH-A nrPDB 45 1e-04 5UWY-A nrPDB 44 1e-04 3OC4-A nrPDB 44 2e-04 3KLJ-A nrPDB 43 3e-04 2V3B-A nrPDB 42 4e-04 6BWT-A nrPDB 42 5e-04 5XHU-A nrPDB 42 6e-04 3F8P-A nrPDB 42 8e-04 5U63-A nrPDB 40 0.002 5W4C-A nrPDB 40 0.003 5NA1-A nrPDB 39 0.004 2A87-A nrPDB 39 0.005 2ZBW-A nrPDB 37 0.018 4ZN0-A nrPDB 37 0.019 3AB1-A nrPDB 36 0.042 5USX-A nrPDB 35 0.057 1NAA-A nrPDB 33 0.20 3RHA-A nrPDB 33 0.29 1F6M-A nrPDB 32 0.50 4JNQ-A nrPDB 32 0.52 3BHF-A nrPDB 32 0.68 3NIX-A nrPDB 32 0.83 6HA8-c nrPDB 32 0.85 3COX-A nrPDB 31 0.91 1REO-A nrPDB 31 0.98 2HJH-A nrPDB 31 1.5 3KVE-A nrPDB 30 1.5 3KRZ-A nrPDB 30 1.7 2EW2-A nrPDB 30 1.7 1ZOV-A nrPDB 30 1.8 1XHC-A nrPDB 30 1.8 1F8S-A nrPDB 30 1.8 4IAO-A nrPDB 30 2.0 5YGQ-A nrPDB 30 2.4 3ATQ-A nrPDB 30 2.6 2QA2-A nrPDB 30 2.7 6BPY-A nrPDB 30 3.1 3IHM-A nrPDB 29 4.2 2GMH-A nrPDB 29 4.4 5BR7-A nrPDB 29 5.0 1VDC-A nrPDB 28 6.5 3WFI-A nrPDB 28 7.6 6CR0-A nrPDB 28 8.2 2D1C-A nrPDB 28 8.2 4YKF-A nrPDB 28 8.7 5L3D-A nrPDB 28 8.8 4CBQ-A nrPDB 28 9.0 2BRY-A nrPDB 28 9.1 5KXJ-A nrPDB 28 9.9 >3II4-A nrPDB Length = 466 Score = 943 bits (2438), Expect = 0.0, Method: Compositional matrix adjust. Identities = 464/464 (100%), Positives = 464/464 (100%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH 60 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH Sbjct: 3 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH 62 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT Sbjct: 63 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 122 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG 180 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG Sbjct: 123 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG 182 Query: 181 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD 240 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD Sbjct: 183 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD 242 Query: 241 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN 300 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN Sbjct: 243 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN 302 Query: 301 VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL 360 VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL Sbjct: 303 VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL 362 Query: 361 TEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELL 420 TEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELL Sbjct: 363 TEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELL 422 Query: 421 PELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 PELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF Sbjct: 423 PELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 466 >1EBD-A nrPDB Length = 455 Score = 300 bits (767), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 179/450 (39%), Positives = 257/450 (57%), Gaps = 5/450 (1%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTK 64 + +V+GAGPGGYVAAIRAAQLG IVE GGVCLNVGCIPSKAL+ +A + K Sbjct: 5 ETLVVGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALI-SASHRYEQAK 63 Query: 65 DAKAFGISGE-VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV 123 ++ GI E VT D+ + V + GV L+K NK+ + G F DANT+ V Sbjct: 64 HSEEMGIKAENVTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAYFVDANTVRV 123 Query: 124 DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIG 183 +N ++ TF NAIIATGS +P S ++ + E+PKS+++ G G IG Sbjct: 124 -VNGDSAQTYTFKNAIIATGSRPIELPNFKFSNRILDSTGALNLGEVPKSLVVIGGGYIG 182 Query: 184 MEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGS 243 +E G N+G VTI+E L + ++ I+K+ KK GV ++T + + Sbjct: 183 IELGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKKRLKKKGVEVVTNALAKGAEERED 242 Query: 244 QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGH 303 VTVT +G + + A+ VL +G PN + GL++ G+ +T+R I VD RT+V + Sbjct: 243 GVTVTYEANGETKTIDADYVLVTVGRRPNTDELGLEQIGIKMTNRGLIEVDQQCRTSVPN 302 Query: 304 IYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQ 363 I+AIGD+ LAH A +G VAAE IAG + D+ +P F P AS G EQ Sbjct: 303 IFAIGDIVPGPALAHKASYEGKVAAEAIAGHPSAV--DYVAIPAVVFSDPECASVGYFEQ 360 Query: 364 QARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPEL 423 QA++EG DV+ AKFPF AN +A + D GF+KLV + G ++G ++G + ++++ EL Sbjct: 361 QAKDEGIDVIAAKFPFAANGRALALNDTDGFLKLVVRKEDGVIIGAQIIGPNASDMIAEL 420 Query: 424 TLAQRWDLTASELARNVHTHPTMSEALQEC 453 LA +TA ++A +H HPT+ E E Sbjct: 421 GLAIEAGMTAEDIALTIHAHPTLGEIAMEA 450 >3URH-A nrPDB Length = 491 Score = 295 bits (755), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 175/462 (37%), Positives = 259/462 (56%), Gaps = 13/462 (2%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY-WGGVCLNVGCIPSKALLRNAELV 59 M YD++V+G+GPGGYV AI+AAQLG+ A+VE + +GG CLNVGCIPSKALL +E+ Sbjct: 23 MMAYDLIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGGTCLNVGCIPSKALLHASEMF 82 Query: 60 HIFTKDAKAFGI---SGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFA 116 H +A G+ + ++ +A+ + + V GV FL KKNKI G G Sbjct: 83 HQAQHGLEALGVEVANPKLNLQKMMAHKDA--TVKSNVDGVSFLFKKNKIDGFQGTGKVL 140 Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLS---ANVVTYEEQILSRELPKS 173 + V G + + N +IATGS +PG ++ +V+ + ++P S Sbjct: 141 GQGKVSVTNEKGEEQVLEAKNVVIATGSDVAGIPGVEVAFDEKTIVSSTGALALEKVPAS 200 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 +I+ G G IG+E G V G VT+VEFL L D +V+K++++ K G+ Sbjct: 201 MIVVGGGVIGLELGSVWARLGAKVTVVEFLDTILGGMDGEVAKQLQRMLTKQGIDFKLGA 260 Query: 234 KVE-SIADG-GSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAI 291 KV ++ G G++VT K G A L AE VL A G P+ +G GL KAGV L R + Sbjct: 261 KVTGAVKSGDGAKVTFEPVKGGEATTLDAEVVLIATGRKPSTDGLGLAKAGVVLDSRGRV 320 Query: 292 GVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFC 351 +D + +T++ +YAIGDV LAH AE +GV AE IAG ++ ++P + Sbjct: 321 EIDRHFQTSIAGVYAIGDVVRGPMLAHKAEDEGVAVAEIIAGQAGHV--NYDVIPGVVYT 378 Query: 352 QPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHL 411 QP VAS G TE++ + G + KFPFTAN +A + GFVK++AD + +LGGH+ Sbjct: 379 QPEVASVGKTEEELKAAGVAYKIGKFPFTANGRARAMLQTDGFVKILADKETDRVLGGHI 438 Query: 412 VGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQEC 453 +G E++ E+ + + ++ +L R H HPTMSEA++E Sbjct: 439 IGFGAGEMIHEIAVLMEFGGSSEDLGRTCHAHPTMSEAVKEA 480 >2YQU-A nrPDB Length = 455 Score = 286 bits (733), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 172/452 (38%), Positives = 249/452 (55%), Gaps = 11/452 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIF 62 YD++V+GAGPGGYVAAIRAAQLG+ +VE K GG CL VGCIPSKALL E ++ Sbjct: 2 YDLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGGTCLRVGCIPSKALLETTERIYEA 61 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 K + G V D KV + GV FL KKN I G F +L Sbjct: 62 KKGLLGAKVKG-VELDLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTARFLSERKVL 120 Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVPGTSLS-ANVVTYEEQILSRELPKSIIIAGAGA 181 V+ E + +IATGS+ + P + VVT E + E+PK +I+ G G Sbjct: 121 VEETG---EELEARYILIATGSAPLIPPWAQVDYERVVTSTEALSFPEVPKRLIVVGGGV 177 Query: 182 IGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADG 241 IG+E G V G +V ++E++ R LP D +VS+ E+ FKK G+TI T +V ++ Sbjct: 178 IGLELGVVWHRLGAEVIVLEYMDRILPTMDLEVSRAAERVFKKQGLTIRTGVRVTAVVPE 237 Query: 242 GSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNV 301 V + V L+A++VL A+G P EG L+ AG++ +R I VD+++RT V Sbjct: 238 AKGARVELEGGEV---LEADRVLVAVGRRPYTEGLSLENAGLSTDERGRIPVDEHLRTRV 294 Query: 302 GHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLT 361 HIYAIGDV LAH A +G+ A E + D++ +P + P +A+ G T Sbjct: 295 PHIYAIGDVVRGPMLAHKASEEGIAAVEHMV--RGFGHVDYQAIPSVVYTHPEIAAVGYT 352 Query: 362 EQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLP 421 E++ + +G V KFP++A+ +A +G+ GF+K++A AK +LG H +G V ++L Sbjct: 353 EEELKAQGIPYKVGKFPYSASGRARAMGETEGFIKVLAHAKTDRILGVHGIGARVGDVLA 412 Query: 422 ELTLAQRWDLTASELARNVHTHPTMSEALQEC 453 E LA + +A +L R H HP++SE L+E Sbjct: 413 EAALALFFKASAEDLGRAPHAHPSLSEILKEA 444 >6AON-A nrPDB Length = 478 Score = 280 bits (717), Expect = 7e-76, Method: Compositional matrix adjust. Identities = 176/476 (36%), Positives = 253/476 (53%), Gaps = 18/476 (3%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW---------GGVCLNVGCIPSKALL 53 +DVVV+GAGPGGY+AAIRAAQLG+S A ++ W GG C NVGCIPSKALL Sbjct: 7 QFDVVVIGAGPGGYIAAIRAAQLGMSVACIDA--WQNGQGGPAPGGTCTNVGCIPSKALL 64 Query: 54 RNAELVHIFTKDAKAFGISGE-VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGY 112 +++E GI + V+ R V + G+ +L KKNK+T HG Sbjct: 65 QSSEHYEQANHHFAEHGIEVKGVSLKLDTLIGRKNTVVKQNNDGILYLFKKNKVTYFHGK 124 Query: 113 GTFADANTLLVDLNDGGTESVTF--DNAIIATGSSTRLVPGTSL-SANVVTYEEQILSRE 169 G FA + GT + I+ATGSS R +PG N+++ + + Sbjct: 125 GAFAGQVDGGWSIKVTGTTDADLVAKHVIVATGSSARELPGLPFDEKNILSNDGALNIGA 184 Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTI 229 +PK + + GAG IG+E G V + G +VTI+E +P L D V+KE K F K G+ I Sbjct: 185 VPKKLGVIGAGVIGLEMGSVWRRLGAEVTILEAMPEFLAAADQQVAKEALKSFAKQGLDI 244 Query: 230 LTATKVESIADGGSQVTVT-VTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDR 288 T K+ I +TV V G Q+L +K++ +IG P G + G+ L +R Sbjct: 245 QTGVKIGEIKAAAKSITVPYVDAKGAEQKLVVDKLIVSIGRVPYTGGLNAEAVGLKLDER 304 Query: 289 KAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRA 348 + VD+ +TN+ +++A+GDV LAH AE +GV AE IAG + +P Sbjct: 305 GFVAVDEDCKTNLPNVWAVGDVVRGPMLAHKAEEEGVAVAERIAGQHGHV--NFATVPWV 362 Query: 349 TFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLG 408 + P +A G TEQQ + EG + FPF AN +A +GD +GF K++ADAK E+LG Sbjct: 363 IYTSPEIAWVGKTEQQLKAEGREYKAGSFPFMANGRARALGDTTGFAKVIADAKTDEVLG 422 Query: 409 GHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 H++G +EL+ E + A ++AR H HPT+SEA++E + +NF Sbjct: 423 VHIIGPMASELISEAVTIMEFRGAAEDIARICHAHPTLSEAVKEAALAVDKRTLNF 478 >5TR3-A nrPDB Length = 481 Score = 278 bits (710), Expect = 5e-75, Method: Compositional matrix adjust. Identities = 176/460 (38%), Positives = 247/460 (53%), Gaps = 13/460 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY--------WGGVCLNVGCIPSKALLRN 55 +DVVV+GAGPGGYVAAI+AAQLGL TA +E KY GG CLNVGCIPSKALL + Sbjct: 8 FDVVVIGAGPGGYVAAIKAAQLGLKTACIE-KYTDAEGKLALGGTCLNVGCIPSKALLDS 66 Query: 56 AELVHIFTKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGT 114 + + GIS GEV D R + + GV L K N +T I G+G Sbjct: 67 SWKYKEAKESFNVHGISTGEVKMDVAAMVGRKAGIVKNLTGGVATLFKANGVTSIQGHGK 126 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILS-RELPKS 173 + V DG TE + +N I+A+GS +P + NV+ L + +PK Sbjct: 127 LLAGKKVEVTKADGTTEVIEAENVILASGSRPIDIPPAPVDQNVIVDSTGALEFQAVPKR 186 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + + GAG IG+E G V G +VT++E L L D VSKE +K K G+ I Sbjct: 187 LGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTKQGLDIKLGA 246 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 +V G++V VT T Q++ +K++ A+G P +GV + +R I V Sbjct: 247 RVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRPVTTDLLASDSGVTIDERGYIFV 306 Query: 294 DDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 DDY T+V +YAIGDV + LAH A +G++ E I G + ++ ++P + P Sbjct: 307 DDYCATSVPGVYAIGDVVRGMMLAHKASEEGIMVVERIKGHKAQM--NYDLIPSVIYTHP 364 Query: 354 NVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVG 413 +A G TEQ + EG +V V FPF A+ +A D GFVK++ADAK +LG H++G Sbjct: 365 EIAWVGKTEQALKAEGVEVNVGTFPFAASGRAMAANDTGGFVKVIADAKTDRVLGVHVIG 424 Query: 414 HDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQEC 453 AEL+ + +A + +A +L V +HPT+SEAL E Sbjct: 425 PSAAELVQQGAIAMEFGTSAEDLGMMVFSHPTLSEALHEA 464 >5U8W-A nrPDB Length = 481 Score = 277 bits (708), Expect = 8e-75, Method: Compositional matrix adjust. Identities = 177/471 (37%), Positives = 254/471 (53%), Gaps = 13/471 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY--------WGGVCLNVGCIPSKALLRN 55 +DVVV+GAGPGGYVAAIRAAQLGL TA +E KY GG CLNVGCIPSKALL + Sbjct: 8 FDVVVIGAGPGGYVAAIRAAQLGLKTACIE-KYIGKEGKVALGGTCLNVGCIPSKALLDS 66 Query: 56 AELVHIFTKDAKAFGISGE-VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGT 114 + H + K GI + VT D R + + G+ L K N +T G+G Sbjct: 67 SYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGK 126 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILS-RELPKS 173 + V DG T+ + +N IIA+GS +P L+ +++ L + +PK Sbjct: 127 LLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKK 186 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + + GAG IG+E G V G +VT++E L + LP D ++KE K K G+ I Sbjct: 187 LGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGA 246 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 +V + QVTVT T Q+ +K++ A+G P +GV L +R I V Sbjct: 247 RVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYV 306 Query: 294 DDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 DD+ +T+V ++AIGDV LAH A +GV+ AE IAG + ++ ++P + P Sbjct: 307 DDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQM--NYDLIPSVIYTHP 364 Query: 354 NVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVG 413 +A G TEQ + EG +V V FPF A+ +A D +G VK++ADAK +LG H++G Sbjct: 365 EIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIG 424 Query: 414 HDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 AEL+ + + + +A +L V +HPT+SEAL E + GH I+ Sbjct: 425 PSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHI 475 >3LAD-A nrPDB Length = 476 Score = 275 bits (704), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 175/470 (37%), Positives = 251/470 (53%), Gaps = 13/470 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY--------WGGVCLNVGCIPSKALLRN 55 +DV+V+GAGPGGYVAAI++AQLGL TA++E KY GG CLNVGCIPSKALL + Sbjct: 4 FDVIVIGAGPGGYVAAIKSAQLGLKTALIE-KYKGKEGKTALGGTCLNVGCIPSKALLDS 62 Query: 56 AELVHIFTKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGT 114 + H + K GIS GEV D R ++ GV L+K N +T G+G Sbjct: 63 SYKFHEAHESFKLHGISTGEVAIDVPTMIARKDQIVRNLTGGVASLIKANGVTLFEGHGK 122 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILS-RELPKS 173 + V DG ++ + +N I+A+GS +P + +V+ L + +P Sbjct: 123 LLAGKKVEVTAADGSSQVLDTENVILASGSKPVEIPPAPVDQDVIVDSTGALDFQNVPGK 182 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + + GAG IG+E G V G +VT++E + + LP D V+KE +K K G+ IL Sbjct: 183 LGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLKILLGA 242 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 +V QVTV + +K++ A+G P +GV L +R I V Sbjct: 243 RVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYV 302 Query: 294 DDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 DDY T+V +YAIGDV LAH A +GVV AE IAG + ++ ++P + P Sbjct: 303 DDYCATSVPGVYAIGDVVRGAMLAHKASEEGVVVAERIAGHKAQM--NYDLIPAVIYTHP 360 Query: 354 NVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVG 413 +A G TEQ + EG + V FPF A+ +A D +GFVK++ADAK +LG H++G Sbjct: 361 EIAGVGKTEQALKAEGVAINVGVFPFAASGRAMAANDTAGFVKVIADAKTDRVLGVHVIG 420 Query: 414 HDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMIN 463 AEL+ + +A + +A +L V HP +SEAL E + GH I+ Sbjct: 421 PSAAELVQQGAIAMEFGTSAEDLGMMVFAHPALSEALHEAALAVSGHAIH 470 >5J5Z-A nrPDB Length = 496 Score = 275 bits (702), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 168/469 (35%), Positives = 247/469 (52%), Gaps = 11/469 (2%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHI-F 62 DV V+G+GPGGYVAAI+AAQLG T +E + GG CLNVGCIPSKALL N+ H+ Sbjct: 30 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAH 89 Query: 63 TKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTL 121 KD + GI EV + ++ + G+ L K+NK+ ++GYG N + Sbjct: 90 GKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQV 149 Query: 122 LVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILS-RELPKSIIIAGAG 180 DGGT+ + N +IATGS PG ++ + + LS +++P+ +++ GAG Sbjct: 150 TATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAG 209 Query: 181 AIGMEFGYVLKNYGVDVTIVEFLPR-ALPNEDADVSKEIEKQFKKLGVTILTATKVESI- 238 IG+E G V + G DVT VEFL D ++SK ++ +K G TKV Sbjct: 210 VIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGAT 269 Query: 239 --ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY 296 +DG V++ G A+ + + +L IG P + GL++ G+ L R I V+ Sbjct: 270 KKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTR 329 Query: 297 MRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVA 356 +T + +IYAIGDV LAH AE +G++ E +AG D+ +P + P VA Sbjct: 330 FQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHI--DYNCVPSVIYTHPEVA 387 Query: 357 SFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDV 416 G +E+Q + EG + V KFPF AN++A D G VK++ +LG H++G Sbjct: 388 WVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGA 447 Query: 417 AELLPELTLAQRWDLTASELARNVHTHPTMSEALQEC-FHGLVGHMINF 464 E++ E LA + + +AR H HPT+SEA +E G INF Sbjct: 448 GEMVNEAALALEYGASCEVIARVCHAHPTLSEAFREANLAASFGKSINF 496 >1DXL-A nrPDB Length = 470 Score = 273 bits (699), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 168/453 (37%), Positives = 249/453 (54%), Gaps = 7/453 (1%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-YWGGVCLNVGCIPSKALLRNAELVHIFT 63 DVV++G GPGGYVAAI+AAQLG T +E + GG CLNVGCIPSKALL ++ + H Sbjct: 8 DVVIIGGGPGGYVAAIKAAQLGFKTTCIEKRGALGGTCLNVGCIPSKALLHSSHMYHEAK 67 Query: 64 KDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 G+ V D + K G+ L KKNK+T + GYG F + + Sbjct: 68 HSFANHGVKVSNVEIDLAAMMGQKDKAVSNLTRGIEGLFKKNKVTYVKGYGKFVSPSEIS 127 Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVPGTSL-SANVVTYEEQILSRELPKSIIIAGAGA 181 VD +G V + IIATGS + +PG ++ +V+ + E+PK +++ GAG Sbjct: 128 VDTIEGENTVVKGKHIIIATGSDVKSLPGVTIDEKKIVSSTGALALSEIPKKLVVIGAGY 187 Query: 182 IGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADG 241 IG+E G V G +VT+VEF +P DA++ K+ ++ +K G+ TKV + Sbjct: 188 IGLEMGSVWGRIGSEVTVVEFASEIVPTMDAEIRKQFQRSLEKQGMKFKLKTKVVGVDTS 247 Query: 242 GSQVTVTVTKDGVAQE--LKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRT 299 G V +TV ++ ++A+ VL + G P G LDK GV I V++ T Sbjct: 248 GDGVKLTVEPSAGGEQTIIEADVVLVSAGRTPFTSGLNLDKIGVETDKLGRILVNERFST 307 Query: 300 NVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFG 359 NV +YAIGDV LAH AE GV E +AG + D+ +P + P VAS G Sbjct: 308 NVSGVYAIGDVIPGPMLAHKAEEDGVACVEYLAG--KVGHVDYDKVPGVVYTNPEVASVG 365 Query: 360 LTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAEL 419 TE+Q + G + V KFPF AN++A + + G VK++A+ + ++LG H++ + EL Sbjct: 366 KTEEQVKETGVEYRVGKFPFMANSRAKAIDNAEGLVKIIAEKETDKILGVHIMAPNAGEL 425 Query: 420 LPELTLAQRWDLTASELARNVHTHPTMSEALQE 452 + E +A ++D ++ ++AR H HPTMSEA++E Sbjct: 426 IHEAAIALQYDASSEDIARVCHAHPTMSEAIKE 458 >2QAE-A nrPDB Length = 468 Score = 271 bits (694), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 169/454 (37%), Positives = 242/454 (53%), Gaps = 9/454 (1%) Query: 18 AAIRAAQLGLSTAIVEPK-YWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGE-- 74 A+I+AAQLG+ TA VE + GG CLNVGCIPSKALL L H + +G+ G Sbjct: 17 ASIKAAQLGMKTACVEKRGALGGTCLNVGCIPSKALLHATHLYHDAHANFARYGLMGGEG 76 Query: 75 VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVT 134 VT D + + +G GV +L KKNK+T G G+F A+++ V+ DG E + Sbjct: 77 VTMDSAKMQQQKERAVKGLTGGVEYLFKKNKVTYYKGEGSFETAHSIRVNGLDGKQEMLE 136 Query: 135 FDNAIIATGSSTRLVPGTSLSANVVTYEEQILS-RELPKSIIIAGAGAIGMEFGYVLKNY 193 IIATGS +P VV L+ +PK++++ G G IG+E G V Sbjct: 137 TKKTIIATGSEPTELPFLPFDEKVVLSSTGALALPRVPKTMVVIGGGVIGLELGSVWARL 196 Query: 194 GVDVTIVEFLPRALPNEDADVSKEIEKQF-KKLGVTILTATKVESIADGGSQVTVTVT-K 251 G +VT+VEF PR P D DV+ + K + +T+TKV + G V++ V K Sbjct: 197 GAEVTVVEFAPRCAPTLDEDVTNALVGALAKNEKMKFMTSTKVVGGTNNGDSVSLEVEGK 256 Query: 252 DGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDV- 310 +G + + E +L ++G P G GLDK VA +R + + D+ T++ +YAIGDV Sbjct: 257 NGKRETVTCEALLVSVGRRPFTGGLGLDKINVAKNERGFVKIGDHFETSIPDVYAIGDVV 316 Query: 311 NGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGY 370 + LAH AE +GV AE +AG ++ ++P + P VAS G +E + + EG Sbjct: 317 DKGPMLAHKAEDEGVACAEILAGKPGHV--NYGVIPAVIYTMPEVASVGKSEDELKKEGV 374 Query: 371 DVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWD 430 V KFPF AN++A V GFVK++ D +LG H+V EL+ E LA + Sbjct: 375 AYKVGKFPFNANSRAKAVSTEDGFVKVLVDKATDRILGVHIVCTTAGELIGEACLAMEYG 434 Query: 431 LTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 ++ ++ R H HPTMSEAL+E L INF Sbjct: 435 ASSEDVGRTCHAHPTMSEALKEACMALFAKTINF 468 >1V59-A nrPDB Length = 478 Score = 271 bits (692), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 175/465 (37%), Positives = 248/465 (53%), Gaps = 20/465 (4%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-YWGGVCLNVGCIPSKALLRNAELVHIF 62 +DVV++G GP GYVAAI+AAQLG +TA VE + GG CLNVGCIPSKALL N+ L H Sbjct: 6 HDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSHLFHQM 65 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRV----AGVHFLMKKNKITEIHGYGTFADA 118 +A+ GI +V D I +K + V G+ L KKNK+T G G+F D Sbjct: 66 HTEAQKRGI--DVNGDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGSFEDE 123 Query: 119 NTLLVDLNDGGTESVTFD------NAIIATGSSTRLVPGTSLSANVVTYEEQILS-RELP 171 + V DG +V D N I+ATGS PG + + LS +E+P Sbjct: 124 TKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTGALSLKEIP 183 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 K + I G G IG+E G V G VT+VEF P+ + D +V+K +K KK G+ Sbjct: 184 KRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLKKQGLDFKL 243 Query: 232 ATKVESIADGGS----QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 +TKV S ++ V TK + L+AE +L A+G P + G G +K G+ + Sbjct: 244 STKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDK 303 Query: 288 RKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPR 347 R + +DD + HI +GDV LAH AE +G+ A E + ++ +P Sbjct: 304 RGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEMLKTGHGHV--NYNNIPS 361 Query: 348 ATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELL 407 + P VA G TE+Q + G D + KFPF AN++A D GFVK++ D+K +L Sbjct: 362 VMYSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQDTEGFVKILIDSKTERIL 421 Query: 408 GGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQE 452 G H++G + E++ E LA + +A ++AR H HPT+SEA +E Sbjct: 422 GAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKE 466 >2EQ6-A nrPDB Length = 464 Score = 259 bits (663), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 177/470 (37%), Positives = 252/470 (53%), Gaps = 17/470 (3%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH 60 M YD++V+G GPGGY AAIRAAQLGL VE GGVCLNVGCIP+KALL AE +H Sbjct: 4 MKTYDLIVIGTGPGGYHAAIRAAQLGLKVLAVEAGEVGGVCLNVGCIPTKALLHAAETLH 63 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 K A+ FG+ + D +V + GV L+K N + + G+ Sbjct: 64 -HLKVAEGFGLKAKPELDLKKLGGWRDQVVKKLTGGVGTLLKGNGVELLRGFARLVGPKE 122 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRE-LPKSIIIAGA 179 + V G E + I+ATGS + G +V + E LPK +++ G Sbjct: 123 VEV-----GGERYGAKSLILATGSEPLELKGFPFGEDVWDSTRALKVEEGLPKRLLVIGG 177 Query: 180 GAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKV---E 236 GA+G+E G V + G +VT++E++P LP D + + + + +K G+ + T TK E Sbjct: 178 GAVGLELGQVYRRLGAEVTLIEYMPEILPQGDPETAALLRRALEKEGIRVRTKTKAVGYE 237 Query: 237 SIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY 296 DG V + + G +E+ +KVL A+G P EG GL+KAGV + +R I V+ Sbjct: 238 KKKDG-LHVRLEPAEGGEGEEVVVDKVLVAVGRKPRTEGLGLEKAGVKVDERGFIRVNAR 296 Query: 297 MRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVA 356 M T+V +YAIGD LAH A +G++AAE AG ++ D+++ P + P A Sbjct: 297 METSVPGVYAIGDAARPPLLAHKAMREGLIAAENAAGKDSAF--DYQV-PSVVYTSPEWA 353 Query: 357 SFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDV 416 GLTE++A+ GY V V KFP A+ +A +G G VK+V D + LLG +VG Sbjct: 354 GVGLTEEEAKRAGYKVKVGKFPLAASGRALTLGGAEGMVKVVGDEETDLLLGVFIVGPQA 413 Query: 417 AELLPELTLAQRWDLTASELARNVHTHPTMSEALQ---ECFHGLVGHMIN 463 EL+ E LA T ++LA VH HPT+SE+L E FH H++N Sbjct: 414 GELIAEAALALEMGATLTDLALTVHPHPTLSESLMEAAEAFHKQAIHILN 463 >4JDR-A nrPDB Length = 474 Score = 254 bits (648), Expect = 7e-68, Method: Compositional matrix adjust. Identities = 180/473 (38%), Positives = 256/473 (54%), Gaps = 28/473 (5%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY--WGGVCLNVGCIPSKALLRNAELVHIFT 63 VVVLGAGP GY AA R A LGL T IVE +Y GGVCLNVGCIPSKALL A+++ Sbjct: 9 VVVLGAGPAGYSAAFRCADLGLETVIVE-RYNTLGGVCLNVGCIPSKALLHVAKVI---- 63 Query: 64 KDAKAFGISGEVTFDYGIAYDRSR----KVAEGRVAGVHFLMKKNKITEIHGYGTFADAN 119 ++AKA G V + D+ R KV G+ + K K+ ++G G F AN Sbjct: 64 EEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGAN 123 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTS-LSANVVTYEEQILSRELPKSIIIAG 178 TL V+ +G T + FDNAIIA GS +P + + + +E+P+ +++ G Sbjct: 124 TLEVEGENGKT-VINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLVMG 182 Query: 179 AGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADV----SKEIEKQFKKLGVTILTATK 234 G IG+E G V G + +VE + +P D D+ +K I K+F + T +TA Sbjct: 183 GGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKFNLMLETKVTA-- 240 Query: 235 VESIADGGSQVTVTVT-KDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 VE+ DG + VT+ K A+ + + VL AIG PN + KAGV + DR I V Sbjct: 241 VEAKEDG---IYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRV 297 Query: 294 DDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 D +RTNV HI+AIGD+ G LAH +G VAAE IAG + D +++P + +P Sbjct: 298 DKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYF--DPKVIPSIAYTEP 355 Query: 354 NVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVG 413 VA GLTE++A+ +G A FP+ A+ +A G KL+ D + ++GG +VG Sbjct: 356 EVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVG 415 Query: 414 HDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL---QECFHGLVGHMIN 463 + ELL E+ LA A ++A +H HPT+ E++ E F G + + N Sbjct: 416 TNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPN 468 >6CMZ-A nrPDB Length = 466 Score = 251 bits (641), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 163/468 (34%), Positives = 248/468 (52%), Gaps = 17/468 (3%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 H ++V+G GPGGYVAAIRA QLG+ T +VE GG CLN+GCIPSKAL+ A+ Sbjct: 8 HTTLLVIGGGPGGYVAAIRAGQLGIPTVLVERDRLGGTCLNIGCIPSKALIHVADAFEQA 67 Query: 63 TKDA--KAFGI---SGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFAD 117 A A GI + E+ +A+ + + GV L+KK+ + +HG D Sbjct: 68 CGHAGEGALGIRVRAPEIDIAKSVAWKDG--IVDRLTRGVGALLKKSGVRVLHGEARVID 125 Query: 118 ANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIA 177 T+ V ++ G + ++ ++ATGS +P +VV+ + + LPK +++ Sbjct: 126 GKTVEV-VSAGHAVRIGCEHLLLATGSEPVELPSMPFGGHVVSSTDALSPATLPKRLVVV 184 Query: 178 GAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVES 237 GAG IG+E G V + GVDV++VE R LP DA++ + + +LGV + KV Sbjct: 185 GAGYIGLELGIVYRKLGVDVSVVEAAERVLPAYDAELVRPVADSLARLGVRLWLGHKVLG 244 Query: 238 IADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDR--KAIGVDD 295 + G+ V V DG Q L A++VL A+G P V+G+GL+ + DR +A+ +DD Sbjct: 245 LDKHGA-VRVQAA-DGAEQTLPADRVLVAVGRRPRVDGFGLE---TLMLDRNGRALRIDD 299 Query: 296 YMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNV 355 RT++ +++AIGDV G LAH A AQG + AE IAG + +P F P + Sbjct: 300 TCRTSMRNVWAIGDVAGEPMLAHRAMAQGEMVAELIAGRRRQFM--PAAIPAVCFTDPEI 357 Query: 356 ASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHD 415 + G + A G D + A FPF AN +A + GFV++VA + ++G VG Sbjct: 358 VTAGWSPDDAHAAGVDCLSASFPFAANGRAMTLQATDGFVRVVARRDNHLIVGWQAVGRG 417 Query: 416 VAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMIN 463 V+EL + + ++ +H HPT+ EALQE +GH ++ Sbjct: 418 VSELAAAFSQSLEMGARLEDIGGTIHAHPTLGEALQEAALRALGHALH 465 >1LVL-A nrPDB Length = 458 Score = 241 bits (616), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 156/460 (33%), Positives = 244/460 (53%), Gaps = 30/460 (6%) Query: 16 YVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTK--DAKAFGIS- 72 YVAAIRA QLG+ T +VE + GG CLN+GCIPSKAL+ AE H ++ + GIS Sbjct: 18 YVAAIRAGQLGIPTVLVEGQALGGTCLNIGCIPSKALIHVAEQFHQASRFTEPSPLGISV 77 Query: 73 GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTES 132 D G + + + GV L+KK+ + +HG+ D + VD + Sbjct: 78 ASPRLDIGQSVAWKDGIVDRLTTGVAALLKKHGVKVVHGWAKVLDGKQVEVD-----GQR 132 Query: 133 VTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKN 192 + ++ ++ATGSS+ +P L V++ E + + LP+ +++ G G IG+E G + Sbjct: 133 IQCEHLLLATGSSSVELPMLPLGGPVISSTEALAPKALPQHLVVVGGGYIGLELGIAYRK 192 Query: 193 YGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKD 252 G V++VE R LP D++++ + + KKLG+ + VE +G + D Sbjct: 193 LGAQVSVVEARERILPTYDSELTAPVAESLKKLGIALHLGHSVEGYENG-----CLLAND 247 Query: 253 GVAQELK--AEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDV 310 G +L+ A++VL A+G P +G+ L+ + + + AI +D+ +T++ +++AIGDV Sbjct: 248 GKGGQLRLEADRVLVAVGRRPRTKGFNLECLDLKM-NGAAIAIDERCQTSMHNVWAIGDV 306 Query: 311 NGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRA----TFCQPNVASFGLTEQQAR 366 G LAH A AQG + AE IAG R P A F P V G T +QA Sbjct: 307 AGEPMLAHRAMAQGEMVAEIIAGKA------RRFEPAAIAAVCFTDPEVVVVGKTPEQAS 360 Query: 367 NEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLA 426 +G D +VA+FPF AN +A + SGFV++VA + +LG VG V+EL A Sbjct: 361 QQGLDCIVAQFPFAANGRAMSLESKSGFVRVVARRDNHLILGWQAVGVAVSEL--STAFA 418 Query: 427 QRWDLTAS--ELARNVHTHPTMSEALQECFHGLVGHMINF 464 Q ++ A ++A +H HPT+ EA+QE +GH ++ Sbjct: 419 QSLEMGACLEDVAGTIHAHPTLGEAVQEAALRALGHALHI 458 >6BZ0-A nrPDB Length = 480 Score = 239 bits (611), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 158/469 (33%), Positives = 241/469 (51%), Gaps = 10/469 (2%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY------WGGVCLNVGCIPSKALLRNA 56 +D+VV+G GPGGY AAIRAAQLG A +E + GG CLNVGCIPSKALL ++ Sbjct: 7 QFDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALLDSS 66 Query: 57 ELVHIFTKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTF 115 GI+ GEV FD R K+ + G+ L+K N I + G G Sbjct: 67 HRYEDTVHHLADHGITTGEVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGIEWLKGTGKL 126 Query: 116 ADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILS-RELPKSI 174 + ++G T+ + I+A+GS +P + +++ L+ E+PK + Sbjct: 127 LAGKKVEFVPHEGETQILEPKYVILASGSVPVNIPVAPVDQDIIVDSTGALNFPEVPKRL 186 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATK 234 + GAG IG+E G V + G +V + E + LP D +SKE +K K G+ I K Sbjct: 187 GVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGLDIRIGAK 246 Query: 235 VESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVD 294 V G +VTV T+ G +E +K++ +G EG + +G+ LT+R + V+ Sbjct: 247 VSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLLAEDSGIKLTERGLVEVN 306 Query: 295 DYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPN 354 D+ T+V +YAIGD+ LAH A +GV+A E I G ++ + + P Sbjct: 307 DHCATSVEGVYAIGDLVRGPMLAHKAMEEGVMAVERIHGHAAQV--NYDTIISIIYTHPE 364 Query: 355 VASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGH 414 A GLTE+QA+ +G++V +F F N +A G+ +GFVK VADAK LLG H++G Sbjct: 365 AAWVGLTEEQAKEKGHEVKTGQFGFAVNGRALAAGEGAGFVKFVADAKTDRLLGMHVIGP 424 Query: 415 DVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMIN 463 ++++ + +A + + +L HPT SE + E + G I+ Sbjct: 425 AASDIVHQGMIALEFVSSVEDLQLMTFGHPTFSEVVHEAALAVDGRAIH 473 >5X1Y-B nrPDB Length = 554 Score = 210 bits (535), Expect = 9e-55, Method: Compositional matrix adjust. Identities = 137/453 (30%), Positives = 241/453 (53%), Gaps = 12/453 (2%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 +YD++++G+G + +AI+A + G ++E GG C+N+GC+PSK LLR E++H+ Sbjct: 84 NYDLLIIGSGAAAFSSAIKAIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEIIHL- 142 Query: 63 TKDAKAFGI---SGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADAN 119 +KD G+ +GEV + + + V+E R L+ + I G F DA+ Sbjct: 143 SKDNPFIGLQTSAGEVDL-ASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDAS 201 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSA-NVVTYEEQILSRELPKSIIIAG 178 T V++N + F +IATG+S L + L + +T + +++PK + + G Sbjct: 202 T--VEVNGAKLSAKRF---LIATGASPSLPQISGLEKMDYLTSTTLLELKKIPKRLTVIG 256 Query: 179 AGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESI 238 +G IGME G + + G ++T+++ R L D ++S+ +EK + G+ ++ E + Sbjct: 257 SGYIGMELGQLFHHLGSEITLMQRSERLLKEYDPEISESVEKALIEQGINLVKGATFERV 316 Query: 239 ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMR 298 G V VT +G + ++++++L A G PN + L AGV I ++D+ + Sbjct: 317 EQSGEIKRVYVTVNGSREVIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEILINDFGQ 376 Query: 299 TNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASF 358 T+ IYA GDV Q +VA +G + + G + D ++P TF P VA+ Sbjct: 377 TSNEKIYAAGDVTLGPQFVYVAAYEGGIITDNAIGGLNKKI-DLSVVPAVTFTNPTVATV 435 Query: 359 GLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAE 418 GLTE+QA+ +GYDV + P A +A + +G KLVADA+ ++LG H+V + + Sbjct: 436 GLTEEQAKEKGYDVKTSVLPLDAVPRAIVNRETTGVFKLVADAETLKVLGVHIVSENAGD 495 Query: 419 LLPELTLAQRWDLTASELARNVHTHPTMSEALQ 451 ++ +LA ++ LT +L + + TM+E L+ Sbjct: 496 VIYAASLAVKFGLTVEDLTETLAPYLTMAEGLK 528 >5U25-A nrPDB Length = 602 Score = 196 bits (497), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 171/464 (36%), Positives = 240/464 (51%), Gaps = 22/464 (4%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHI 61 YDVVVLG GPGGY AA AA GL AIVE K GGVCLNVGCIPSKALL NA ++ Sbjct: 125 EYDVVVLGGGPGGYSAAFAAADEGLKVAIVERYKTLGGVCLNVGCIPSKALLHNAAVID- 183 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVA----GVHFLMKKNKITEIHGYGTFAD 117 + + +G + + D R +G V+ G+ + K K+ I G G F D Sbjct: 184 ---EVRHLAANGIKYPEPELDIDMLRAYKDGVVSRLTGGLAGMAKSRKVDVIQGDGQFLD 240 Query: 118 ANTLLVDLNDGGT----------ESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILS 167 + L V L G + V F N IIA GS +P ++ + Sbjct: 241 PHHLEVSLTAGDAYEQAAPTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALAL 300 Query: 168 RELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGV 227 +E+P ++I G G IG+E G V G + +VE + + D D+ K +KQ + Sbjct: 301 KEVPGKLLIIGGGIIGLEMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYRFD 360 Query: 228 TILTATKVESIADGGSQVTVTVTKDGVAQE-LKAEKVLQAIGFAPNVEGYGLDKAGVALT 286 I+ TK ++ V VT +E + + VL A G APN + +KAGVA+T Sbjct: 361 NIMVNTKTVAVEPKEDGVYVTFEGANAPKEPQRYDAVLVAAGRAPNGKLISAEKAGVAVT 420 Query: 287 DRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLP 346 DR I VD MRTNV HIYAIGD+ G LAH A +G VAAE AG + D R++P Sbjct: 421 DRGFIEVDKQMRTNVPHIYAIGDIVGQPMLAHKAVHEGHVAAENCAGHKAYF--DARVIP 478 Query: 347 RATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGEL 406 + P VA G TE A+ G + A FP+ A+ +A G +GF KL+ DA+ G + Sbjct: 479 GVAYTSPEVAWVGETELSAKASGRKITKANFPWAASGRAIANGCDNGFTKLIFDAETGRI 538 Query: 407 LGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 +GG +VG + +++ E+ LA A+++ + +H HPT+ E++ Sbjct: 539 IGGGIVGPNGGDMIGEVCLAIEMGCDAADIGKTIHPHPTLGESI 582 >4YWO-A nrPDB Length = 462 Score = 194 bits (492), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 144/451 (31%), Positives = 228/451 (50%), Gaps = 24/451 (5%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 + + ++G G G+ A I+A +LG+ ++ GG C+NVGC+PSK +L AE I+ Sbjct: 16 HKLAIIGYGAAGFAAMIKANELGVKPVLIGKGEIGGTCVNVGCVPSKRMLYIAE---IYK 72 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV 123 K + G EV + ++ V E R L+ + I G F + V Sbjct: 73 KAREVTG--SEVYPPFSSFQEKDGLVQEMRKTKYEDLLSYYDVELIQGEARFISPHA--V 128 Query: 124 DLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILSRELPKSIIIAGAGA 181 +N E+ F +IATGSS + +PG T E + S+ + G A Sbjct: 129 KVNGQVIEAEKF---VIATGSSPLIPRIPGLD-KVGFWTNREALSPDRRIDSLAVIGGRA 184 Query: 182 IGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADG 241 + +EF + V+V I++ P +P+ + + S E + + GV ++T V+ + G Sbjct: 185 LALEFAQMYSRMKVEVAILQRSPVLIPDWEPEASVEARRIMENDGVAVVTGVNVKEVRKG 244 Query: 242 GSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNV 301 ++ +T E++A+++L A G PNV+ GL+ AGV L +R I VDD +RT+ Sbjct: 245 AGKIVITDKG-----EVEADEILLATGRKPNVD-LGLENAGVRLNERGGIKVDDELRTDN 298 Query: 302 GHIYAIGDVNGLLQLAHVAEAQGVVAAET-IAGAETLTLGDHRMLPRATFCQPNVASFGL 360 HIYA GDV G L +A QG +A E + G+ D +P+ F QPN+A GL Sbjct: 299 PHIYAAGDVLGGKMLEALAGRQGSIATENALTGSHKRV--DENAVPQVIFTQPNLARVGL 356 Query: 361 TEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELL 420 TE +AR + +V P ++ AKA + GFVK+V +G ++G H VG +VAE++ Sbjct: 357 TEAEARAKEGEVEARVLPMSSVAKAEIINSRLGFVKMV--TMNGRIVGVHAVGENVAEMI 414 Query: 421 PELTLAQRWDLTASELARNVHTHPTMSEALQ 451 E LA R+ T +L VH PT++E+L+ Sbjct: 415 GEAALAIRFGATVHDLIDTVHMFPTIAESLR 445 >1OJT-A nrPDB Length = 482 Score = 191 bits (484), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 169/464 (36%), Positives = 237/464 (51%), Gaps = 22/464 (4%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHI 61 YDVVVLG GPGGY AA AA GL AIVE K GGVCLNVGCIPSKALL NA ++ Sbjct: 6 EYDVVVLGGGPGGYSAAFAAADEGLKVAIVERYKTLGGVCLNVGCIPSKALLHNAAVI-- 63 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVA----GVHFLMKKNKITEIHGYGTFAD 117 + + +G + + D R +G V+ G+ + K K+ I G G F D Sbjct: 64 --DEVRHLAANGIKYPEPELDIDMLRAYKDGVVSRLTGGLAGMAKSRKVDVIQGDGQFLD 121 Query: 118 ANTLLVDLNDGGT----------ESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILS 167 + L V L G + V F N IIA GS +P ++ + Sbjct: 122 PHHLEVSLTAGDAYEQAAPTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALAL 181 Query: 168 RELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGV 227 +E+P ++I G G IG+E G V G + +VE + + D D+ K +KQ + Sbjct: 182 KEVPGKLLIIGGGIIGLEMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYRFD 241 Query: 228 TILTATKVESIADGGSQVTVTVTKDGVAQE-LKAEKVLQAIGFAPNVEGYGLDKAGVALT 286 I+ TK ++ V VT +E + + VL A G APN + +KAGVA+T Sbjct: 242 NIMVNTKTVAVEPKEDGVYVTFEGANAPKEPQRYDAVLVAAGRAPNGKLISAEKAGVAVT 301 Query: 287 DRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLP 346 DR I VD MRTNV HIYAIGD+ G LAH A +G VAAE AG + D R++P Sbjct: 302 DRGFIEVDKQMRTNVPHIYAIGDIVGQPMLAHKAVHEGHVAAENCAGHKAYF--DARVIP 359 Query: 347 RATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGEL 406 + P VA G TE A+ + A FP+ A+ +A G F KL+ DA+ G + Sbjct: 360 GVAYTSPEVAWVGETELSAKASARKITKANFPWAASGRAIANGCDKPFTKLIFDAETGRI 419 Query: 407 LGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 +GG +VG + +++ E+ LA A+++ + +H HPT+ E++ Sbjct: 420 IGGGIVGPNGGDMIGEVCLAIEMGCDAADIGKTIHPHPTLGESI 463 >2R9Z-A nrPDB Length = 463 Score = 174 bits (442), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 136/458 (29%), Positives = 220/458 (48%), Gaps = 27/458 (5%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 H+D++ +G G GG A +AA G A++E K GG C+NVGC+P K + + L Sbjct: 4 HFDLIAIGGGSGGLAVAEKAAAFGKRVALIESKALGGTCVNVGCVPKKVMWYASHLAEA- 62 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGR---VAGVHFL----MKKNKITEIHGYGTF 115 +DA FG+ G D R VA GR + ++ +++ IT + G+ F Sbjct: 63 VRDAPGFGVQAS-----GGTLDWPRLVA-GRDRYIGAINSFWDGYVERLGITRVDGHARF 116 Query: 116 ADANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILSRELPKS 173 DA+T+ V+ + ++ D+ +IATG + +PG L +T + ++ PK Sbjct: 117 VDAHTIEVE-----GQRLSADHIVIATGGRPIVPRLPGAELG---ITSDGFFALQQQPKR 168 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + I GAG IG+E +L+++G +VT+V R L D +S + + G+ Sbjct: 169 VAIIGAGYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLLSATLAENMHAQGIETHLEF 228 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 V ++ + +Q T V +DG E + V+ A+G APN GL+ AG+ + + Sbjct: 229 AVAAL-ERDAQGTTLVAQDGTRLE-GFDSVIWAVGRAPNTRDLGLEAAGIEVQSNGMVPT 286 Query: 294 DDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 D Y TNV +YA+GD+ G QL VA A G AE + ++ D+ +P F P Sbjct: 287 DAYQNTNVPGVYALGDITGRDQLTPVAIAAGRRLAERLFDGQSERKLDYDNIPTVVFAHP 346 Query: 354 NVASFGLTEQQARNEGYDVV-VAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLV 412 ++ GL+E +AR DV+ V + FT A P +KLV ++G H++ Sbjct: 347 PLSKVGLSEPEARERLGDVLTVYETSFTPMRYALNEHGPKTAMKLVCAGPEQRVVGVHVI 406 Query: 413 GHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 G E+L +A + T ++ V HP +E L Sbjct: 407 GDGADEMLQGFAVAVKMGATKADFDNTVAIHPGSAEEL 444 >1ZK7-A nrPDB Length = 467 Score = 172 bits (437), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 142/464 (30%), Positives = 215/464 (46%), Gaps = 39/464 (8%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKD 65 V V+G+G AA++A + G ++E GG C+NVGC+PSK ++R A + H+ Sbjct: 7 VAVIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHL---- 62 Query: 66 AKAFGISGEVTFDYGIA-----YDRSR-------KVAEGRVAGVHFLMKKNK-ITEIHGY 112 E FD GIA DRS+ +V E R A ++ N IT +HG Sbjct: 63 ------RRESPFDGGIAATVPTIDRSKLLAQQQARVDELRHAKYEGILGGNPAITVVHGE 116 Query: 113 GTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV-TYEEQILSRELP 171 F D +L V LN+GG V FD ++ATG+S + P L + T E + S +P Sbjct: 117 ARFKDDQSLTVRLNEGGERVVMFDRCLVATGASPAVPPIPGLKESPYWTSTEALASDTIP 176 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVE----FLPRALPNEDADVSKEIEKQFKKLGV 227 + + + G+ + +E G VT++ F ED + + + F+ G+ Sbjct: 177 ERLAVIGSSVVALELAQAFARLGSKVTVLARNTLFF-----REDPAIGEAVTAAFRAEGI 231 Query: 228 TILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 +L T+ +A + +T T EL+A+K+L A G PN LD AGV + Sbjct: 232 EVLEHTQASQVAHMDGEFVLTTTHG----ELRADKLLVATGRTPNTRSLALDAAGVTVNA 287 Query: 288 RKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPR 347 + AI +D MRT+ +IYA GD Q +VA A G AA + G + D +P Sbjct: 288 QGAIVIDQGMRTSNPNIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAAL--DLTAMPA 345 Query: 348 ATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELL 407 F P VA+ G +E +A ++G + +A D GF+KLV + L+ Sbjct: 346 VVFTDPQVATVGYSEAEAHHDGIETDSRTLTLDNVPRALANFDTRGFIKLVIEEGSHRLI 405 Query: 408 GGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQ 451 G V + EL+ LA R +T ELA + + TM E L+ Sbjct: 406 GVQAVAPEAGELIQTAALAIRNRMTVQELADQLFPYLTMVEGLK 449 >3O0H-A nrPDB Length = 484 Score = 172 bits (436), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 131/453 (28%), Positives = 220/453 (48%), Gaps = 19/453 (4%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 +D+ V+G+G GG AA A LG AI E GG C+ GC+P K ++ F+ Sbjct: 27 FDLFVIGSGSGGVRAARLAGALGKRVAIAEEYRIGGTCVIRGCVPKKLYFYASQYAQEFS 86 Query: 64 KDAKAFGIS-GEVTFDY-GIAYDRSRKVAEGRVAGVHFLMKKNKITEIH-GYGTFADANT 120 K FG + F++ + ++++++ R+ G++ +N I+ F D +T Sbjct: 87 KSI-GFGWKYADPIFNWEKLVAAKNKEIS--RLEGLYREGLQNSNVHIYESRAVFVDEHT 143 Query: 121 LLVDLNDGGTESVTFDNAIIATGS---STRLVPGTSLSANVVTYEEQILSRELPKSIIIA 177 L + + E ++ + +IATG+ S + G+ L +T E +LPKSI+I Sbjct: 144 LELSVTG---ERISAEKILIATGAKIVSNSAIKGSDLC---LTSNEIFDLEKLPKSIVIV 197 Query: 178 GAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVES 237 G G IG+EF + GV T++ L N D D+ + + G++I+ V Sbjct: 198 GGGYIGVEFANIFHGLGVKTTLLHRGDLILRNFDYDLRQLLNDAMVAKGISIIYEATVSQ 257 Query: 238 IADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYM 297 + + V +T Q + A++V+ A G PN G GL++AGV + + A+ VD+ M Sbjct: 258 VQSTENCYNVVLTN---GQTICADRVMLATGRVPNTTGLGLERAGVKVNEFGAVVVDEKM 314 Query: 298 RTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVAS 357 TNV HI+A+GDV G +QL VA + + A T T D+ ++ A F QP + + Sbjct: 315 TTNVSHIWAVGDVTGHIQLTPVAIHDAMCFVKN-AFENTSTTPDYDLITTAVFSQPEIGT 373 Query: 358 FGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVA 417 GL+E+ A + V + + F F+KLV D + ++G H++G + Sbjct: 374 VGLSEEDALHRYKRVEIYRTVFRPMRNVLSGSPEKMFMKLVVDGESRIVVGAHVLGENAG 433 Query: 418 ELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 E+ + ++ + LT + + HPTMSE L Sbjct: 434 EIAQLIGISLKGKLTKDIFDKTMAVHPTMSEEL 466 >6DU7-A nrPDB Length = 448 Score = 172 bits (435), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 136/448 (30%), Positives = 218/448 (48%), Gaps = 42/448 (9%) Query: 21 RAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGI-SGEVTFDY 79 RA + G A++E K GG C+NVGC+P K + A++ F + + +G + ++ FD+ Sbjct: 21 RAGEHGAQAAVIEEKKLGGTCVNVGCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDF 80 Query: 80 GI------AY-DRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTES 132 +Y DR+R +G K+N + I G+ F D++T+ V+ E Sbjct: 81 ATLRRNRESYIDRARSSYDGS-------FKRNGVDLIEGHAEFVDSHTVSVN-----GEL 128 Query: 133 VTFDNAIIATGSSTRL--VPGTSL---SANVVTYEEQILSRELPKSIIIAGAGAIGMEFG 187 + + +IATG+ + +PG L S +V +EE LP+S+ I GAG I +E Sbjct: 129 IRAKHIVIATGAHPSIPNIPGAELGGSSDDVFAWEE------LPESVAILGAGYIAVELA 182 Query: 188 YVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT---ATKVESIADGGSQ 244 VL +GV + R L D+ + + + K+ ++ + + T K+E DG Sbjct: 183 GVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEMERTNLPLHTHKVPVKLEKTTDG--- 239 Query: 245 VTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHI 304 +T+ +DG + A +V+ A G PNV+G L+KAGV L +R I VD+Y T V I Sbjct: 240 ITIHF-EDGTSH--TASQVIWATGRRPNVKGLQLEKAGVTLNERGFIQVDEYQNTVVEGI 296 Query: 305 YAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQ 364 YA+GDV G +L VA G +E + +T D+ +P F P + + GLTE+Q Sbjct: 297 YALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDYSTIPTVVFSHPAIGTVGLTEEQ 356 Query: 365 ARNE-GYDVV-VAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPE 422 A E G D + V K F + A KL+ +++G H +G+ V E++ Sbjct: 357 AIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLITAGSEEKVVGLHGIGYGVDEMIQG 416 Query: 423 LTLAQRWDLTASELARNVHTHPTMSEAL 450 +A + T ++ V HPT SE Sbjct: 417 FAVAIKMGATKADFDATVAIHPTSSEEF 444 >4DNA-A nrPDB Length = 463 Score = 167 bits (423), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 142/454 (31%), Positives = 221/454 (48%), Gaps = 20/454 (4%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 YD+ V+G G GG + AA LG AI E +GG C+ GC+P K + ++ F Sbjct: 6 YDLFVIGGGSGGVRSGRLAAALGKKVAIAEEFRYGGTCVIRGCVPKKLYVYASQFAEHF- 64 Query: 64 KDAKAFGIS-GEVTFDYG-IAYDRSRKVAEGRVAGVHFLMKKNKITEI-HGYGTFADANT 120 +DA FG + GE FD+ + + +++A R+ G++ N EI A NT Sbjct: 65 EDAAGFGWTVGESRFDWAKLVAAKEQEIA--RLEGLYRKGLANAGAEILDTRAELAGPNT 122 Query: 121 LLVDLNDGGTESVTFDNAIIATG---SSTRLVPGTSLSANVVTYEEQILSRELPKSIIIA 177 + + L G T VT + +IA G S +PG L +T E LP+SI+IA Sbjct: 123 VKL-LASGKT--VTAERIVIAVGGHPSPHDALPGHEL---CITSNEAFDLPALPESILIA 176 Query: 178 GAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVES 237 G G I +EF + GV T++ L D D+ + + ++ G+ IL ++S Sbjct: 177 GGGYIAVEFANIFHGLGVKTTLIYRGKEILSRFDQDMRRGLHAAMEEKGIRILCEDIIQS 236 Query: 238 I-ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY 296 + AD + T K G E+ A++V+ A+G PN G GL+ AGV + AI VD + Sbjct: 237 VSADADGRRVATTMKHG---EIVADQVMLALGRMPNTNGLGLEAAGVRTNELGAIIVDAF 293 Query: 297 MRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVA 356 RT+ IYA+GDV +QL VA + + ET T DH ++ A F QP + Sbjct: 294 SRTSTPGIYALGDVTDRVQLTPVAIHEAMCFIET-EYKNNPTSPDHDLIATAVFSQPEIG 352 Query: 357 SFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDV 416 + G+TE++A + ++ V + F +KLV +A +++G H++GHD Sbjct: 353 TVGITEEEAARKFQEIEVYRAEFRPMKATLSGRKEKTIMKLVVNAADRKVVGAHILGHDA 412 Query: 417 AELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 E+ L ++ R T + R + HPT +E L Sbjct: 413 GEMAQLLGISLRAGCTKDDFDRTMAVHPTAAEEL 446 >6N7F-A nrPDB Length = 453 Score = 160 bits (404), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 131/451 (29%), Positives = 209/451 (46%), Gaps = 13/451 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 YD +V+G G G +A RAA G + E K GG C+N+GC+P K + A++ I Sbjct: 8 YDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVNLGCVPKKVMWYGAQVADILG 67 Query: 64 KDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRV-AGVHFLMKKNKITEIHGYGTFADANTL 121 AK +G E FD+ +R+ R+ A ++N + I+ Y F DA+T+ Sbjct: 68 TYAKDYGFDFKEKAFDFK-QLKANRQAYIDRIHASYERGFEQNGVDRIYDYAVFKDAHTV 126 Query: 122 LVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGA 181 + + T + +IATG + P + ++ + E+PK + GAG Sbjct: 127 EI-----AGQLYTAPHILIATGGHP-VFPDIEGAQYGISSDGFFALDEVPKRTAVVGAGY 180 Query: 182 IGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADG 241 I +E VL G + R L + D + + + G + T +V + Sbjct: 181 IAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHTHAEVAKVVKN 240 Query: 242 GSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNV 301 + KDG QE++ ++++ AIG PN+EG+ LDK GV L D+ I D Y T+V Sbjct: 241 TDESLTLYLKDG--QEVEVDQLIWAIGRKPNLEGFSLDKTGVTLNDKGYIETDAYENTSV 298 Query: 302 GHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLT 361 IYA+GDVNG L L VA A G +E + +T D++ + F P + S GL+ Sbjct: 299 KGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKLDYQNVATVIFSHPVIGSVGLS 358 Query: 362 EQQA-RNEGYDVV-VAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAEL 419 E+ A + G + V + FT+ A +KLV +++G H +G+ V E+ Sbjct: 359 EEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMKLVTVGDTEKIVGLHGIGYGVDEM 418 Query: 420 LPELTLAQRWDLTASELARNVHTHPTMSEAL 450 + +A + T ++ V HPT SE Sbjct: 419 IQGFAVAIKMGATKADFDNTVAIHPTGSEEF 449 >6B4O-A nrPDB Length = 452 Score = 157 bits (397), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 135/464 (29%), Positives = 218/464 (46%), Gaps = 33/464 (7%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH 60 M YD +V+G G GG +A RA G + ++E GG C+NVGC+P K + + + ++ Sbjct: 4 MKTYDYIVIGGGSGGIASANRAGMHGANVLLIEGNEIGGTCVNVGCVPKKVMWQASSMME 63 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFL-------MKKNKITEIHGYG 113 + +D +G FD I +++ E R + FL + N I IHGY Sbjct: 64 MMERDTAGYG------FDVEIKNFSFKQLVENREKYIDFLHGAYNRGLDSNNIERIHGYA 117 Query: 114 TFADANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILSRELP 171 TF T+ V+ GTE T + +IATG + +PG + + + E+P Sbjct: 118 TFTGEQTIEVN----GTE-YTAPHILIATGGRPKKLGIPGEEYALDSNGF---FALEEMP 169 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTI-- 229 K ++ GAG I E L G + R L + D +S+++ ++++++G+ I Sbjct: 170 KRVVFVGAGYIAAELAGTLHGLGAETHWAFRHERPLRSFDDMLSEKVVERYQEMGMQIHP 229 Query: 230 -LTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDR 288 T K+E A +T ++G + + + V+ G PN + GL+ VAL ++ Sbjct: 230 NATPAKIEKTAQNEYVITF---ENG--ESITTDAVIFGTGRQPNTDQLGLENTKVALDEK 284 Query: 289 KAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRA 348 + VD + T IYA+GDV G + L VA A G +E + +T D+ ++P Sbjct: 285 GYVKVDKFQNTTQNGIYAVGDVIGKIDLTPVAIAAGRRLSERLFNGQTDLYLDYNLVPTV 344 Query: 349 TFCQPNVASFGLTEQQARNE-GYDVV-VAKFPFTANAKAHGVGDPSGFVKLVADAKHGEL 406 F P VA+ GLTE+ A E G D V + + FT A G +KL+ K ++ Sbjct: 345 VFTHPPVATIGLTEKAALEEYGEDQVKIYRSSFTPMYFALGEYRQKCDMKLICVGKEEKI 404 Query: 407 LGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 +G H +G V E+L +A + T ++ V HPT SE Sbjct: 405 VGLHGIGIGVDEMLQGFAVAIKMGATKADFDNTVAIHPTGSEEF 448 >2YAU-A nrPDB Length = 511 Score = 151 bits (382), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 135/474 (28%), Positives = 214/474 (45%), Gaps = 37/474 (7%) Query: 4 YDVVVLGAGPGGYVAAIRAA-QLGLSTAIVE------PKYW---GGVCLNVGCIPSKALL 53 YD+VVLGAG GG A AA A+V+ P + GG C+NVGC+P K ++ Sbjct: 25 YDLVVLGAGSGGLEAGWNAAVTHKKKVAVVDVQATHGPPLFAALGGTCVNVGCVPKKLMV 84 Query: 54 RNAELVHIFTKDAKAFGISGE---VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIH 110 A+ + + +++ FG + + ++ KV + + H Sbjct: 85 TGAQYMDLI-RESGGFGWEMDRESLCPNWKTLIAAKNKVVNSINESYKSMFADTEGLSFH 143 Query: 111 -GYGTFADANTLLV----DLNDGGTESVTFDNAIIATGS-STRL-VPGTSLSANVVTYEE 163 G+G DA+T++V D + E++ + +IATGS TRL VPG +T E Sbjct: 144 MGFGALQDAHTVVVRKSEDPHSDVLETLDTEYILIATGSWPTRLGVPGDEF---CITSNE 200 Query: 164 QILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA---LPNEDADVSKEIEK 220 + PK ++ G G I +EF + Y V+ R L D +V K + K Sbjct: 201 AFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPCGGYVDLCYRGDLILRGFDTEVRKSLTK 260 Query: 221 QFKKLGVTI---LTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYG 277 Q G+ + L TK+ DG + V DG ++ ++V+ AIG P + Sbjct: 261 QLGANGIRVRTNLNPTKITKNEDGSNHVHF---NDGTEEDY--DQVMLAIGRVPRSQALQ 315 Query: 278 LDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETL 337 LDKAGV A+ VD Y +T+V +IYAIGDV + L VA +G ET+ G + Sbjct: 316 LDKAGVRTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGAAFVETVFGGKPR 375 Query: 338 TLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTA-NAKAHGVGDPSGFVK 396 DH + A F P + + G+TE++A V V FT G ++ Sbjct: 376 AT-DHTKVACAVFSIPPIGTCGMTEEEAAKNYETVAVYASSFTPLMHNISGSKHKEFMIR 434 Query: 397 LVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 ++ + +GE+LG H++G E++ + + + S+ + HPT +E L Sbjct: 435 IITNESNGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTIGVHPTSAEEL 488 >1GEU-A nrPDB Length = 450 Score = 150 bits (380), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 131/456 (28%), Positives = 208/456 (45%), Gaps = 21/456 (4%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAEL---V 59 HYD + +G G GG + RAA G A++E K GG C+NVGC+P K + A++ + Sbjct: 4 HYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVNVGCVPKKVMWHAAQIREAI 63 Query: 60 HIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRV-AGVHFLMKKNKITEIHGYGTFADA 118 H++ D + ++ IA SR R+ ++ KN + I G+ F DA Sbjct: 64 HMYGPDYGFDTTINKFNWETLIA---SRTAYIDRIHTSYENVLGKNNVDVIKGFARFVDA 120 Query: 119 NTLLVDLNDGGTESVTFDNAIIATG--SSTRLVPGTSLSANVVTYEEQILSRELPKSIII 176 TL V+ E++T D+ +IATG S +PG + + LP+ + + Sbjct: 121 KTLEVN-----GETITADHILIATGGRPSHPDIPGVEYGIDSDGF---FALPALPERVAV 172 Query: 177 AGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVE 236 GAG IG+E G V+ G + E LP+ D +S+ + + G + T + Sbjct: 173 VGAGYIGVELGGVINGLGAKTHLFEMFDAPLPSFDPMISETLVEVMNAEGPQLHTNAIPK 232 Query: 237 SIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY 296 ++ +DG ++ + ++ AIG P + L+ AGV ++ I VD Y Sbjct: 233 AVVKNTDGSLTLELEDGRSETVDC--LIWAIGREPANDNINLEAAGVKTNEKGYIVVDKY 290 Query: 297 MRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVA 356 TN+ IYA+GD G ++L VA A G +E + + D+ +P F P + Sbjct: 291 QNTNIEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHLDYSNIPTVVFSHPPIG 350 Query: 357 SFGLTEQQARNEGYD--VVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGH 414 + GLTE QAR + D V V K FTA A +KLV +++G H +G Sbjct: 351 TVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMKLVCVGSEEKIVGIHGIGF 410 Query: 415 DVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 + E+L +A + T + V HPT +E Sbjct: 411 GMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEF 446 >3L8K-A nrPDB Length = 466 Score = 149 bits (375), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 135/458 (29%), Positives = 217/458 (47%), Gaps = 23/458 (5%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-YWGGVCLNVGCIPSKALLRNAELVHIF 62 YDVVV+GAG GY A R A+ + + +PK GG CL GC+PSK + + Sbjct: 5 YDVVVIGAGGAGYHGAFRLAKAKYNVLMADPKGELGGNCLYSGCVPSKTVREVIQTAWRL 64 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNK-ITEIHGYGTFADANTL 121 T A ++ D+ DR V E R M + + +T GY D + Sbjct: 65 TNIANV-----KIPLDFSTVQDRKDYVQELRFKQHKRNMSQYETLTFYKGYVKIKDPTHV 119 Query: 122 LVDLNDGGTESVTFDNAIIATGSST---RLVPGTSL---SANVVTYEEQILSRELPKSII 175 +V ++G IIA+G+ T RL PG S ++ Y+ R+LP+ ++ Sbjct: 120 IVKTDEGKEIEAETRYMIIASGAETAKLRL-PGVEYCLTSDDIFGYKTSF--RKLPQDMV 176 Query: 176 IAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVSKEIEKQFKKLGVTILT-AT 233 I GAG IG+E + + GV I+E L RAL ED D+ + KL + + T Sbjct: 177 IIGAGYIGLEIASIFRLMGVQTHIIEMLDRALITLEDQDIVNTL-LSILKLNIKFNSPVT 235 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 +V+ I D +V + TKDG + + V+ A G P + G + G++++ + I V Sbjct: 236 EVKKIKDDEYEVIYS-TKDGSKKSIFTNSVVLAAGRRPVIPE-GAREIGLSIS-KTGIVV 292 Query: 294 DDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETI-AGAETLTLGDHRMLPRATFCQ 352 D+ M+TN+ +++A GD NGL H A + AA I A + D + +P + Sbjct: 293 DETMKTNIPNVFATGDANGLAPYYHAAVRMSIAAANNIMANGMPVDYVDVKSIPVTIYTI 352 Query: 353 PNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLV 412 P+++ G+ +AR G ++V A++ + A G G +KL+ + L+G ++ Sbjct: 353 PSLSYVGILPSKARKMGIEIVEAEYNMEEDVSAQIYGQKEGVLKLIFERGSMRLIGAWMI 412 Query: 413 GHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 G L+ EL LA + L A +LA HP+ +E + Sbjct: 413 GVHSQYLINELGLAVAYGLNAKQLASFAEQHPSTNEII 450 >2WOV-A nrPDB Length = 495 Score = 147 bits (372), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 136/486 (27%), Positives = 207/486 (42%), Gaps = 61/486 (12%) Query: 4 YDVVVLGAGPGGYVAAIRAAQL-GLSTAIVE------PKYW---GGVCLNVGCIPSKALL 53 +D+VV+GAG GG A AA L G A+V+ P ++ GG C+NVGC+P K ++ Sbjct: 8 FDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMV 67 Query: 54 RNAELVHIFTKDA----------------KAFGISGEVTFDYGIAYDRSRKVAEGRVAGV 97 A+ + + A K E D +Y+ EG + Sbjct: 68 TGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEG----L 123 Query: 98 HFLMKKNKITEIHGYGTFADANTLLV----DLNDGGTESVTFDNAIIATGSSTRL--VPG 151 F + G+G+ N ++V D E + D+ ++ATGS ++ +PG Sbjct: 124 DFFL---------GWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPG 174 Query: 152 TSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNY---GVDVTIVEFLPRALP 208 + ++ E E P+ ++ G G I +EF + Y G VT+ L Sbjct: 175 IE---HCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILR 231 Query: 209 NEDADVSKEIEKQFKKLGVTILT---ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQ 265 D + +E+ KQ G+ I+T KV DG VT K L + V+ Sbjct: 232 GFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDGSKHVTFESGK-----TLDVDVVMM 286 Query: 266 AIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGV 325 AIG P L GV LT + + VD++ RTNV +IYAIGD+ L L VA +G Sbjct: 287 AIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGA 346 Query: 326 VAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKA 385 +T+ G + DH + A F P + + GL E+ A E V V FT Sbjct: 347 ALVDTVFGNKPRKT-DHTRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHN 405 Query: 386 HGVGDPSGFV-KLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHP 444 FV K+V + G +LG HL+G E++ + + R + S+ + HP Sbjct: 406 ISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHP 465 Query: 445 TMSEAL 450 T +E L Sbjct: 466 TSAEEL 471 >1XDI-A nrPDB Length = 499 Score = 145 bits (366), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 133/470 (28%), Positives = 213/470 (45%), Gaps = 22/470 (4%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTA---IVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 +V+LG GP GY AA+ AA T +++ GG + C+PSK + + L Sbjct: 5 IVILGGGPAGYEAALVAATSHPETTQVTVIDCDGIGGAAVLDDCVPSKTFIASTGL---R 61 Query: 63 TKDAKAFGISGEVTFD-----YGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFAD 117 T+ +A + + FD + R + +A + A + + + I G G D Sbjct: 62 TELRRAPHLGFHIDFDDAKISLPQIHARVKTLAAAQSADITAQLLSMGVQVIAGRGELID 121 Query: 118 ANTLLVDLN------DGGTESVTFDNAIIATGSSTRLVPGTSLSA-NVVTYEEQILSREL 170 + L DG T D ++ATG+S R++P ++T+ + L Sbjct: 122 STPGLARHRIKATAADGSTSEHEADVVLVATGASPRILPSAQPDGERILTWRQLYDLDAL 181 Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL 230 P +I+ G+G G EF GV VT+V LP EDAD + +E+ F + GV + Sbjct: 182 PDHLIVVGSGVTGAEFVDAYTELGVPVTVVASQDHVLPYEDADAALVLEESFAERGVRLF 241 Query: 231 TATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKA 290 + S+ G+ V VT+T DG + ++ L IG PN G GL++ G+ L Sbjct: 242 KNARAASVTRTGAGVLVTMT-DG--RTVEGSHALMTIGSVPNTSGLGLERVGIQLGRGNY 298 Query: 291 IGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATF 350 + VD RT IYA GD GLL LA VA QG +A G E ++ R + F Sbjct: 299 LTVDRVSRTLATGIYAAGDCTGLLPLASVAAMQGRIAMYHALG-EGVSPIRLRTVAATVF 357 Query: 351 CQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGH 410 +P +A+ G+ + P NA+A GFVK+ G ++GG Sbjct: 358 TRPEIAAVGVPQSVIDAGSVAARTIMLPLRTNARAKMSEMRHGFVKIFCRRSTGVVIGGV 417 Query: 411 LVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGH 460 +V +EL+ + +A + +T +ELA+ + +P++S ++ E L+ H Sbjct: 418 VVAPIASELILPIAVAVQNRITVNELAQTLAVYPSLSGSITEAARRLMAH 467 >5VDN-A nrPDB Length = 463 Score = 142 bits (358), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 128/462 (27%), Positives = 208/462 (45%), Gaps = 33/462 (7%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAEL---V 59 HYD + +G G GG + RAA G A++E K GG C+NVGC+P K + A++ + Sbjct: 17 HYDYLAIGGGSGGIASINRAAMYGKKCALIEAKQLGGTCVNVGCVPKKVMWHAAQIAEAI 76 Query: 60 HIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFL-------MKKNKITEIHGY 112 H++ D +G FD + + +K+ R A + + + NK+ I G+ Sbjct: 77 HLYGPD---YG------FDTTVNHFDWKKLIANRTAYIDRIHQSYERGLGNNKVDVIQGF 127 Query: 113 GTFADANTLLVDLNDGGTESVTFDNAIIATG--SSTRLVPGTSLSANVVTYEEQILSREL 170 F DA+T+ V+ E++T D+ +IATG S +PG + + E E+ Sbjct: 128 ARFVDAHTVEVN-----GETITADHILIATGGRPSHPDIPGAEYGIDSDGFFEL---DEM 179 Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL 230 PK + + GAG I +E VL G + + L D + + + + G + Sbjct: 180 PKRVAVVGAGYIAVEIAGVLNGLGTETHLFVRKHAPLRTFDPLIVETLLEVMNTEGPKLH 239 Query: 231 TATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKA 290 T + +++ ++G E+ + ++ AIG P + L GV D+ Sbjct: 240 TESVPKAVIKNADGSLTLQLENGT--EVTVDHLIWAIGREPATDNLNLSVTGVKTNDKGY 297 Query: 291 IGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATF 350 I VD + TNV IYA+GD G+++L VA A G +E + + D+ +P F Sbjct: 298 IEVDKFQNTNVKGIYAVGDNTGVVELTPVAVAAGRRLSERLFNNKPDEHLDYSNIPTVVF 357 Query: 351 CQPNVASFGLTEQQARNEGYD--VVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLG 408 P + + GLTE QAR + D V V FTA A +KLV +++G Sbjct: 358 SHPPIGTIGLTEPQAREKFGDDQVKVYTSSFTAMYSAVTQHRQPCRMKLVCVGAEEKIVG 417 Query: 409 GHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 H +G + E+L +A + T + V HPT +E Sbjct: 418 IHGIGFGMDEILQGFAVAMKMGATKKDFDNTVAIHPTAAEEF 459 >5V36-A nrPDB Length = 453 Score = 140 bits (354), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 125/454 (27%), Positives = 210/454 (46%), Gaps = 17/454 (3%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 YD +V+G G GG +A RAA G + E K GG C+NVGC+P K + A++ Sbjct: 7 QYDYIVIGGGSGGIASANRAAMHGAKVILFEGKQVGGTCVNVGCVPKKVMWYGAQVAETI 66 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKK----NKITEIHGYGTFADA 118 A +G +VT +D ++ + + +H ++ N + ++GY TF DA Sbjct: 67 NNYAADYGF--DVTTQ-AFHFDVLKQNRQAYIDRIHDSYERGFDSNGVERVYGYATFVDA 123 Query: 119 NTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAG 178 +T+ V E T + +IATG L+P S +T + +PK + G Sbjct: 124 HTVEV-----AGEHYTAPHILIATGGHA-LLPDIPGSEYGITSDGFFELDAIPKRTAVVG 177 Query: 179 AGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESI 238 AG I +E +L G + + R L D ++ + + KK G + T + + + Sbjct: 178 AGYIAVEISGILHALGSETHLFVRRDRPLRKFDKEIVGTLVDEMKKDGPHLHTFSVPKEV 237 Query: 239 ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMR 298 + ++G +E + ++ AIG A N +G+ L+ GV L R I D + Sbjct: 238 IKNTDNSLTLILENG--EEYTVDTLIWAIGRAANTKGFNLEVTGVTLDSRGFIATDAFEN 295 Query: 299 TNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASF 358 TNV +YA+GDVNG L+L VA G +E + + D++ + F P + S Sbjct: 296 TNVEGLYALGDVNGKLELTPVAVKAGRQLSERLFNHKPQAKMDYKDVATVIFSHPVIGSI 355 Query: 359 GLTEQQARNE--GYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDV 416 GL+E+ A ++ +V V + FT+ A + +KLV + +++G H +G+ V Sbjct: 356 GLSEEAALDQYGEENVTVYRSTFTSMYTAVTSHRQACKMKLVTVGEDEKIVGLHGIGYGV 415 Query: 417 AELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 E++ +A + T ++ V HPT SE Sbjct: 416 DEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEF 449 >2HQM-A nrPDB Length = 479 Score = 140 bits (352), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 127/466 (27%), Positives = 205/466 (43%), Gaps = 27/466 (5%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 HYD +V+G G GG +A RAA G T +VE K GG C+NVGC+P K + ++L Sbjct: 11 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA-TR 69 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFL-------MKKNKITEIHGYGTF 115 A +G+ + D + + R A VH L ++K K+ + G+ F Sbjct: 70 VSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARF 129 Query: 116 ADANTLLVDLNDGGTESVTFDNAIIATGSSTRL---VPGTSL---SANVVTYEEQILSRE 169 + V D TE + ++ ++ATG +PG L S EEQ Sbjct: 130 NKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQ----- 184 Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTI 229 PK +++ GAG IG+E V G + +V L D + I + K G+ + Sbjct: 185 -PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINV 243 Query: 230 LTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRK 289 +K+ + + + + ++++ IG ++ G G + G+ L Sbjct: 244 HKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHD 302 Query: 290 AIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLG--DHRMLPR 347 I D+Y TNV +IY++GDV G ++L VA A G + + G E D+ +P Sbjct: 303 QIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPS 362 Query: 348 ATFCQPNVASFGLTEQQARNEGY---DVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHG 404 F P S G++E++A E Y ++ V FTA A K+V + Sbjct: 363 VIFSHPEAGSIGISEKEAI-EKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNE 421 Query: 405 ELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 +++G H+VG AE+L +A + T ++ V HPT +E L Sbjct: 422 KVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 467 >2AAQ-A nrPDB Length = 479 Score = 139 bits (349), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 137/469 (29%), Positives = 215/469 (45%), Gaps = 37/469 (7%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI-F 62 YD +V+G G GG +A RAA+LG A+VE GG C+NVGC+P K + A VH F Sbjct: 22 YDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTA--VHSEF 79 Query: 63 TKDAKAFGI-SGEVTFDYGIAYDRSRKVAEGRVAGVHFL-------MKKNKITEIHGYGT 114 D +G S E F++ R + E R A V L + K+ I I G+ Sbjct: 80 MHDHADYGFPSCEGKFNW-------RVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAA 132 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATG--SST---RLVPGTSLSANVVTYEEQILSRE 169 F ++++ + T + +IATG ST +PG SL +T + E Sbjct: 133 FTSDPKPTIEVSG---KKYTAPHILIATGGMPSTPHESQIPGASLG---ITSDGFFQLEE 186 Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTI 229 LP +I GAG I +E +L G +++ + L + D+ +S ++ + GV + Sbjct: 187 LPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEV 246 Query: 230 LTATKVESIAD--GGSQVTVTVTKDGVAQEL----KAEKVLQAIGFAPNVEGYGLDKAGV 283 L ++V+ + G +V++ G + + +L AIG PN + L+K G+ Sbjct: 247 LKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGI 306 Query: 284 ALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHR 343 D+ I VD++ TNV IYA+GDV G L VA A G A + + + D+ Sbjct: 307 QTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYN 366 Query: 344 MLPRATFCQPNVASFGLTEQQARNEG--YDVVVAKFPFTANAKAHGVGDPSGFVKLVADA 401 +P F P + + GLTE +A ++ +V FT A +K+V Sbjct: 367 NIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCAN 426 Query: 402 KHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 K +++G H+ G E+L +A + T ++ V HPT SE L Sbjct: 427 KEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 475 >4NEW-A nrPDB Length = 492 Score = 137 bits (346), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 131/487 (26%), Positives = 213/487 (43%), Gaps = 64/487 (13%) Query: 4 YDVVVLGAGPGGYVAAIRAAQL-GLSTAIVE------PKYW---GGVCLNVGCIPSKALL 53 +D+VV+GAG GG AA AA L A+++ P ++ GG C+NVGC+P K ++ Sbjct: 6 FDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMV 65 Query: 54 RNAELVHIFTKDAKAFG-----------------ISGEVTFDYGIAYDRSRKVAEGRVAG 96 A+ + +++ FG + E + +YD + EG Sbjct: 66 TGAQYME-HLRESAGFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEG---- 120 Query: 97 VHFLMKKNKITEIHGYGTFADANTLLV----DLNDGGTESVTFDNAIIATGSSTRL--VP 150 + F + G+G+ N + V D E + ++ ++A+GS + +P Sbjct: 121 LEFFL---------GWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIP 171 Query: 151 GTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGV---DVTIVEFLPRAL 207 G + ++ E E P+ ++ G G I +EF + Y VT+ L Sbjct: 172 GIE---HCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMIL 228 Query: 208 PNEDADVSKEIEKQFKKLGVTILT---ATKVESIADGGSQVTVTVTKDGVAQELKAEKVL 264 D + +E+ KQ G+ ILT KVE ADG VT K ++ + V+ Sbjct: 229 RGFDHTLREELTKQLTANGIQILTKENPAKVELNADGSKSVTFESGK-----KMDFDLVM 283 Query: 265 QAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQG 324 AIG +P + L AGV + + + VD+Y RTNV +IYAIGDV + L VA + Sbjct: 284 MAIGRSPRTKDLQLQNAGVMIKN-GGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEA 342 Query: 325 VVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTA-NA 383 +T+ G T DH + A F P + + GL E+ A V V FT Sbjct: 343 AALVDTVFGT-TPRKTDHTRVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMH 401 Query: 384 KAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTH 443 K G + K++ + G +LG HL+G + E++ + + + + S+ + H Sbjct: 402 KVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVH 461 Query: 444 PTMSEAL 450 PT +E L Sbjct: 462 PTSAEEL 468 >1FEC-A nrPDB Length = 490 Score = 135 bits (341), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 135/476 (28%), Positives = 211/476 (44%), Gaps = 41/476 (8%) Query: 4 YDVVVLGAGPGGYVAAIRAAQL-GLSTAIVE-------PKY--WGGVCLNVGCIPSKALL 53 YD+VV+GAG GG A AA L A+++ P Y GG C+NVGC+P K ++ Sbjct: 4 YDLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPKKLMV 63 Query: 54 RNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGR-VAGVH-----FLMKKNKIT 107 A + + A G E+ + ++ A+ + V+G++ +T Sbjct: 64 TGANYMDTIRESA---GFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTEGLT 120 Query: 108 EIHGYGTFADANTLLV----DLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTY 161 G+G D +T+LV D N E++ + ++ATGS + + G L +T Sbjct: 121 FHQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHLGIEGDDL---CITS 177 Query: 162 EEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA---LPNEDADVSKEI 218 E E PK + G G I +EF + Y V+ R L D+++ K++ Sbjct: 178 NEAFYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRKQL 237 Query: 219 EKQFKKLGVTILT---ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEG 275 +Q + G+ + T KV ADG V V + G E + V+ AIG P + Sbjct: 238 TEQLRANGINVRTHENPAKVTKNADGTRHV---VFESGA--EADYDVVMLAIGRVPRSQT 292 Query: 276 YGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAE 335 L+KAGV + AI VD Y +TNV +IYAIGDV + L VA +G +T+ A Sbjct: 293 LQLEKAGVEVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVF-AN 351 Query: 336 TLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTA-NAKAHGVGDPSGF 394 DH + A F P + G E+ A + V V + FT G Sbjct: 352 KPRATDHTKVACAVFSIPPMGVCGYVEEDAAKKYDQVAVYESSFTPLMHNISGSTYKKFM 411 Query: 395 VKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 V++V + GE+LG H++G E++ + + + S+ + HPT +E L Sbjct: 412 VRIVTNHADGEVLGVHMLGDSSPEIIQSVAICLKMGAKISDFYNTIGVHPTSAEEL 467 >5U1O-A nrPDB Length = 458 Score = 132 bits (331), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 126/458 (27%), Positives = 213/458 (46%), Gaps = 22/458 (4%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61 TH+D + +G G GG +A RAA G A++E + GG C+NVGC+P K + A++ Sbjct: 10 THFDYICIGGGSGGIASANRAAMYGAKVALIEAQDLGGTCVNVGCVPKKVMWHGAQIAEA 69 Query: 62 FTKDAKAFGISGEVT-FDYGIAYDRSRKVAEGRV-AGVHFLMKKNKITEIHGYGTFADAN 119 A+ +G +V FD+ + SR+ GR+ ++ NK+ I G+ F D Sbjct: 70 MNLYAEDYGFDVDVKGFDWSKLVE-SRQAYIGRIHQSYDRVLGNNKVNVIKGFAKFVDEK 128 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILSRELPKSIIIA 177 T+ V+ E T D+ +IA G + +PG + + + E PK + + Sbjct: 129 TVEVN-----GEHYTADHILIAVGGRPTIPNIPGAEYGIDSNGFFDL---AEQPKRVAVV 180 Query: 178 GAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT-ATKVE 236 GAG I +E VL G + + L + D + + + + G T+ T + E Sbjct: 181 GAGYIAVEIAGVLHALGTETHLFVRKESPLRSFDPMIIDTLVEVMEAEGPTLHTHSVPKE 240 Query: 237 SIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY 296 + + +T+ + ++G +Q + ++++ AIG P + L GVA ++ I VD+Y Sbjct: 241 VVKEADGSLTLHL-ENGESQNV--DQLIWAIGRHPATDAINLASTGVATNEKGYIKVDEY 297 Query: 297 MRTNVGHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNV 355 TNV IY +GD+ G ++L VA G +E + + D+ ++P F P + Sbjct: 298 QETNVKGIYCVGDIMEGGIELTPVAVKAGRQLSERLFNNKPNAKMDYDLVPTVVFSHPPI 357 Query: 356 ASFGLTEQQARNEGY---DVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLV 412 + GLT Q+A E Y ++ V FTA A +KLV + ++G H + Sbjct: 358 GTIGLTTQEAE-EKYGKDNIKVYTSGFTAMYTAVTKHRQPCKMKLVCAGEEETVVGLHGI 416 Query: 413 GHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 G V E++ +A + T ++ V HPT SE Sbjct: 417 GFTVDEMIQGFGVAMKMGATKADFDSVVAIHPTGSEEF 454 >3IC9-A nrPDB Length = 492 Score = 129 bits (325), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 122/461 (26%), Positives = 190/461 (41%), Gaps = 24/461 (5%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAI-VEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 DV ++G G G + A RAA+ + +E +G C VGC+PSK L+ A+ + Sbjct: 10 DVAIIGTGTAG-MGAYRAAKKHTDKVVLIEGGAYGTTCARVGCMPSKLLIAAADASY-HA 67 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAG--VHFLMKKNKITEIHGYGTFADANTL 121 FGI + G A + + R G V + ++ +I G+ F D +TL Sbjct: 68 SQTDLFGIQVDRISVNGKAVMKRIQTERDRFVGFVVESVESFDEQDKIRGFAKFLDEHTL 127 Query: 122 LVDLNDGGTESVTFDNAIIATGSSTRL-----VPGTSLSANVVTYEEQILSRELPKSIII 176 VD V +IATGS G+ L N +E +LPKS+ + Sbjct: 128 QVD----DHSQVIAKRIVIATGSRPNYPEFLAAAGSRLLTNDNLFE----LNDLPKSVAV 179 Query: 177 AGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVE 236 G G IG+E G L GV V + +D ++ + EK F + A + Sbjct: 180 FGPGVIGLELGQALSRLGVIVKVFGRSGSVANLQDEEMKRYAEKTFNEEFYFDAKARVIS 239 Query: 237 SIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY 296 +I + + K G + VL A G NV+ GL+ + L + + D+ Sbjct: 240 TIEKEDAVEVIYFDKSGQKTTESFQYVLAATGRKANVDKLGLENTSIELDKKNSPLFDEL 299 Query: 297 -MRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNV 355 ++T+V HI+ GD N L L H A G VA + G R F +P V Sbjct: 300 TLQTSVDHIFVAGDANNTLTLLHEAADDGKVAGTNAGAYPVIAQGQRRAPLSVVFTEPQV 359 Query: 356 ASFGLTEQQ-----ARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGH 410 AS GL+ +Q A + + VV + F ++ +G G + + AD GE LG Sbjct: 360 ASVGLSLRQIEDLYADQDAANYVVGQVSFEGQGRSRVMGKNKGLLNVYADRTSGEFLGAE 419 Query: 411 LVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQ 451 + G + L A++ +T + HP + E L+ Sbjct: 420 MFGPAAEHIGHLLAWARQQQMTVQAMLTMPFYHPVIEEGLR 460 >2NVK-X nrPDB Length = 488 Score = 120 bits (302), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 139/480 (28%), Positives = 213/480 (44%), Gaps = 55/480 (11%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTA---IVEPK-----YWG--GVCLNVGCIPSKALL 53 YD++V+G G G A A G A V+P WG G C+NVGCIP K L+ Sbjct: 10 YDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKK-LM 68 Query: 54 RNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKV--AEGRVAGVHFL----MKKNKIT 107 A L+ +A A+G + D I D + V + + V+++ ++ K+ Sbjct: 69 HQASLLGEAVHEAAAYGWN----VDDKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVE 124 Query: 108 EIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQI 165 I+G G+F D++TLL L G ++T +IA G R +PG ++ + + + Sbjct: 125 YINGLGSFVDSHTLLAKLKS-GERTITAQTFVIAVGGRPRYPDIPG-AVEYGITSDDLFS 182 Query: 166 LSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKL 225 L RE P ++ GAG IG+E LK G + T++ L D +++ + ++ Sbjct: 183 LDRE-PGKTLVVGAGYIGLECAGFLKGLGYEPTVM-VRSIVLRGFDQQMAELVAASMEER 240 Query: 226 GVTILTAT---KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAG 282 G+ L T VE DG V + G E + VL AIG V+ L AG Sbjct: 241 GIPFLRKTVPLSVEKQDDGKLLVKYKNVETGEESEDVYDTVLWAIGRKGLVDDLNLPNAG 300 Query: 283 VALTDRKAIGVDDYMRTNVGHIYAIGD-VNGLLQLAHVAEAQGVVAAETIAGAETLTLGD 341 V + K I VD TNV +IYA+GD + G +L VA G + A + G T + D Sbjct: 301 VTVQKDK-IPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRM-D 358 Query: 342 HRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGF------- 394 ++ + F A GL+E+ A V +F HG P+ F Sbjct: 359 YKDVATTVFTPLEYACVGLSEEDA--------VKQFGADEIEVFHGYYKPTEFFIPQKSV 410 Query: 395 ----VKLVADAKHGE--LLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSE 448 +K VA+ +HG+ + G H +G E++ A + LT + L V HPT +E Sbjct: 411 RYCYLKAVAE-RHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAE 469 >1ZDL-A nrPDB Length = 517 Score = 119 bits (299), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 125/475 (26%), Positives = 209/475 (44%), Gaps = 42/475 (8%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAI---VEPK----YW--GGVCLNVGCIPSKALLR 54 +D++V+G G GG A AAQLG A+ VEP W GG C+NVGCIP K L+ Sbjct: 33 FDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKK-LMH 91 Query: 55 NAELVHIFTKDAKAFG--ISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGY 112 A L+ +DA +G ++ V ++ + + + G ++ K+ + Sbjct: 92 QAALLGGMIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIK 151 Query: 113 GTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANV---VTYEEQILSRE 169 +F D +T+ G ++ ++ +IATG R T + + +T ++ +E Sbjct: 152 ASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYP--TQVKGALEYGITSDDIFWLKE 209 Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNE--DADVSKEIEKQFKKLGV 227 P ++ GA + +E L G+D T+ + R++P D +S + + + G Sbjct: 210 SPGKTLVVGASYVALECAGFLTGIGLDTTV---MMRSIPLRGFDQQMSSLVTEHMESHGT 266 Query: 228 TIL---TATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVA 284 L + ++ + QVT G + VL AIG P L+KAG++ Sbjct: 267 QFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGIS 326 Query: 285 LTDR-KAIGVDDYMRTNVGHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGAETLTLGDH 342 + + I VD T+V HIYAIGDV G +L A G + A+ + G + TL D+ Sbjct: 327 TNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSS-TLMDY 385 Query: 343 RMLPRATFCQPNVASFGLTEQQA-------RNEGYDVVVAKFPFTANAKAHGVGDPS-GF 394 +P F GL+E++A E Y FT + D S + Sbjct: 386 SNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADR-----DASQCY 440 Query: 395 VKLVADAKHGEL-LGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSE 448 +K+V + +L LG H +G + E+ L + + +++ + V HPT SE Sbjct: 441 IKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSE 495 >1ONF-A nrPDB Length = 500 Score = 115 bits (288), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 131/497 (26%), Positives = 218/497 (43%), Gaps = 57/497 (11%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 YD++V+G G GG AA RAA+ A+VE GG C+NVGC+P K + NA VH Sbjct: 3 YDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMF-NAASVHDIL 61 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFL-MKKNKITEIHGYGTFADANTLL 122 ++++ +G + +F+ + +R K + R+ ++ + K+K+ G +F N +L Sbjct: 62 ENSRHYGFDTKFSFNLPLLVERRDKYIQ-RLNNIYRQNLSKDKVDLYEGTASFLSENRIL 120 Query: 123 V----DLN--DGG---TESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKS 173 + D N D G E + N +IA G+ P + N ++ +E +E K Sbjct: 121 IKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPPVKGIE-NTISSDEFFNIKE-SKK 178 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 I I G+G I +E V+K G+D I R L D V +E KK + I+T Sbjct: 179 IGIVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTFA 238 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 V I + DG E + V+ +G +P+ E L+K V T+ I V Sbjct: 239 DVVEIKKVSDKNLSIHLSDGRIYE-HFDHVIYCVGRSPDTENLKLEKLNVE-TNNNYIVV 296 Query: 294 DDYMRTNVGHIYAIG------------DVNGL----------------------LQLAHV 319 D+ RT+V +IYA+G D+N L +QL V Sbjct: 297 DENQRTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPV 356 Query: 320 AEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARN----EGYDVVVA 375 A G + A+ + +T +++++P F P + + GL+E+ A E + + Sbjct: 357 AINAGRLLADRLFLKKTRK-TNYKLIPTVIFSHPPIGTIGLSEEAAIQIYGKENVKIYES 415 Query: 376 KFP--FTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTA 433 KF F + ++KLV K + G H++G + E++ +A + + T Sbjct: 416 KFTNLFFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGFAVALKMNATK 475 Query: 434 SELARNVHTHPTMSEAL 450 + + HPT +E Sbjct: 476 KDFDETIPIHPTAAEEF 492 >4KPR-E nrPDB Length = 499 Score = 113 bits (283), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 108/435 (24%), Positives = 195/435 (44%), Gaps = 37/435 (8%) Query: 38 GGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGV 97 GG C+NVGCIP K L+ A L+ KD++ +G E T + +++ + + + + Sbjct: 56 GGTCVNVGCIPKK-LMHQAALLGQALKDSRNYGWKLEDTVKHD--WEKMTESVQNHIGSL 112 Query: 98 HF----LMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPG 151 ++ +++ K+ + YG F + ++ N G + + + +IATG R +PG Sbjct: 113 NWGYRVALREKKVVYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPG 172 Query: 152 TSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIV--EFLPRALPN 209 ++ ++ P ++ GA + +E L G+DVT++ L R Sbjct: 173 D--KEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGF-- 228 Query: 210 EDADVSKEIEKQFKKLGVTIL---TATKVESIADGGS---QVTVTVTKDGVAQELKAEKV 263 D D++ +I + ++ G+ + TK+E I G +VT T E + V Sbjct: 229 -DQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDEFNTV 287 Query: 264 LQAIGFAPNVEGYGLDKAGVALTDRKA-IGVDDYMRTNVGHIYAIGDV-NGLLQLAHVAE 321 L A+G GL+ GV + ++ I V D +TNV +IYAIGD+ G L+L VA Sbjct: 288 LLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAI 347 Query: 322 AQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARN-------EGYDVVV 374 G + A+ + G T+ D+ +P F GL+E++A E Y Sbjct: 348 QAGRLLAQRLYGGSTVKC-DYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFF 406 Query: 375 AKFPFTANAKAHGVGDPSGFVKLVADAKHGE-LLGGHLVGHDVAELLPELTLAQRWDLTA 433 +T ++ + + K++ + K E ++G H++G + E+ A + LT Sbjct: 407 WPLEWTVPSRDNN----KCYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTK 462 Query: 434 SELARNVHTHPTMSE 448 +L + HP +E Sbjct: 463 QQLDSTIGIHPVCAE 477 >5W1J-A nrPDB Length = 584 Score = 102 bits (254), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 124/481 (25%), Positives = 197/481 (40%), Gaps = 47/481 (9%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE-----P--KYWG--GVCLNVGCIPSKALLR 54 YD+V++G G GG A +A+ G A+++ P WG G C+NVGCIP K L+ Sbjct: 104 YDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGTCVNVGCIPKK-LMH 162 Query: 55 NAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFL-------MKKNKIT 107 A L++ + +DAK+FG +D K+ EG +H L M + Sbjct: 163 QAALLNHYMEDAKSFG------WDVDKGPHDWVKMVEGIQDHIHALNFGYRSSMMNANVK 216 Query: 108 EIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILS 167 ++ G D +T+ G +++T + I+ATG R P +T ++ Sbjct: 217 YLNALGEIVDPHTIKTTNKQGIVKNITTNTIIVATGERPRYPPIPGAKEYGITSDDLFTL 276 Query: 168 RELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIV--EFLPRALPNEDADVSKEIEKQFKKL 225 P + GA + +E L + G DVT++ R D ++ I K Sbjct: 277 DHNPGKTLCVGASYVSLECAGFLSSIGCDVTVMVRSIFLRGF---DQQMAGLISDYIAKY 333 Query: 226 GVTILTATKVESI-------ADGGSQVTVTVT---KDGVAQELKAEKVLQAIGFAPNVEG 275 GV + S+ + G V +DG + VL A+G P Sbjct: 334 GVKFVRPCVPTSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTN 393 Query: 276 YGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGA 334 GL V T+ + + VDD RTNV +IYAIGDV N QL +A G A + A Sbjct: 394 IGLQNVDVKTTNGRVV-VDDEERTNVPNIYAIGDVSNAGYQLTPLAIQAGKNLARRLYTA 452 Query: 335 ETLTLGDHRMLPRATFCQPNVASFGLTEQQARN----EGYDVVVAKFPFTANAKAHGVGD 390 + D+ +P F GL+E+ A + + +V + F H D Sbjct: 453 DDCRT-DYTNVPTTVFTPLEYGCIGLSEENAISKFGEDNIEVFHSYFQPLEWTVPHR-PD 510 Query: 391 PSGFVKLVADAK-HGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEA 449 + + KL+ + + ++G H+ G + E+ +A + R + HPT SE Sbjct: 511 NTCYAKLIINKQDDNRVVGFHVFGPNAGEVTQGYAVAMHLGARKEDFDRTIGIHPTCSET 570 Query: 450 L 450 Sbjct: 571 F 571 >2CFY-A nrPDB Length = 521 Score = 102 bits (254), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 119/480 (24%), Positives = 213/480 (44%), Gaps = 46/480 (9%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAI---VEP----KYW--GGVCLNVGCIPSKALLR 54 YD++++G G GG AA AAQ G + V P W GG C+NVGCIP K L+ Sbjct: 35 YDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKK-LMH 93 Query: 55 NAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHF----LMKKNKITEIH 110 A L+ +D++ +G E T + +DR + + + +++ +++ K+ + Sbjct: 94 QAALLGQALQDSRNYGWKVEETVKHD--WDRMIEAVQNHIGSLNWGYRVALREKKVVYEN 151 Query: 111 GYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILSR 168 YG F + + N G + + + +IATG R +PG ++ ++ Sbjct: 152 AYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGD--KEYCISSDDLFSLP 209 Query: 169 ELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIV--EFLPRALPNEDADVSKEIEKQFKKLG 226 P ++ GA + +E L G+DVT++ L R D D++ +I + ++ G Sbjct: 210 YCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGF---DQDMANKIGEHMEEHG 266 Query: 227 VTIL---TATKVESIADGGSQVTVTVTKDGVAQEL---KAEKVLQAIGFAPNVEGYGLDK 280 + + KVE I G V + ++E+ + V+ AIG GL+ Sbjct: 267 IKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLET 326 Query: 281 AGVALTDRKA-IGVDDYMRTNVGHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGAETLT 338 GV + ++ I V D +TNV +IYAIGD+ ++L VA G + A+ + T+ Sbjct: 327 VGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVK 386 Query: 339 LGDHRMLPRATFCQPNVASFGLTEQQARN-------EGYDVVVAKFPFTANAKAHGVGDP 391 D+ +P F + GL+E++A E Y +T ++ + Sbjct: 387 C-DYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNN---- 441 Query: 392 SGFVKLVADAKHGE-LLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 + K++ + K E ++G H++G + E+ A + LT +L + HP +E Sbjct: 442 KCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVF 501 >2X8H-A nrPDB Length = 598 Score = 98.6 bits (244), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 129/478 (26%), Positives = 212/478 (44%), Gaps = 38/478 (7%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAI---VEPK----YWG--GVCLNVGCIPSKALLR 54 YD++V+G G GG A AA+ G TA+ VEP WG G C+NVGCIP K L+ Sbjct: 108 YDLIVIGGGSGGLAAGKEAAKYGAKTAVLDYVEPTPIGTTWGLGGTCVNVGCIPKK-LMH 166 Query: 55 NAELVHIFTKDAKAFGIS---GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHG 111 A L+ +DA+ FG S +++ ++ + + G ++ N++T ++ Sbjct: 167 QAGLLSHALEDAEHFGWSLDRSKISHNWSTMVEGVQSHIGSLNWGYKVALRDNQVTYLNA 226 Query: 112 YGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILSRE 169 G + + + + ++T + I+ATG + +PG +T ++ Sbjct: 227 KGRLISPHEVQITDKNQKVSTITGNKIILATGERPKYPEIPGAVEYG--ITSDDLFSLPY 284 Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIV--EFLPRALPNEDAD-VSKEIEK---QFK 223 P ++ GA + +E L + G DVT++ L R + A+ V +E +F Sbjct: 285 FPGKTLVIGASYVALECAGFLASLGGDVTVMVRSILLRGFDQQMAEKVGDYMENHGVKFA 344 Query: 224 KLGV----TILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLD 279 KL V L E+ G V T DG E + E V+ A+G P + + Sbjct: 345 KLCVPDEIKQLKVVDTENNKPGLLLVKGHYT-DGKKFEEEFETVIFAVGREPQLSKVLCE 403 Query: 280 KAGVALTDRKAIGVDDYMRTNVGHIYAIGDVN-GLLQLAHVA-EAQGVVAAETIAGAETL 337 GV L + D +T V ++YAIGD+N G QL VA +A +A AGA L Sbjct: 404 TVGVKLDKNGRVVCTDDEQTTVSNVYAIGDINAGKPQLTPVAIQAGRYLARRLFAGATEL 463 Query: 338 TLGDHRMLPRATFCQPNVASFGLTEQQA----RNEGYDVVVAKFPFTANAKAHGVGDPSG 393 T D+ + F + GL+E+ A ++ +V + F AH D Sbjct: 464 T--DYSNVATTVFTPLEYGACGLSEEDAIEKYGDKDIEVYHSNFKPLEWTVAHR-EDNVC 520 Query: 394 FVKLVA-DAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 ++KLV + + +LG H++G + E+ +A + T ++ R + HPT SE Sbjct: 521 YMKLVCRKSDNMRVLGLHVLGPNAGEITQGYAVAIKMGATKADFDRTIGIHPTCSETF 578 >4LA1-A nrPDB Length = 602 Score = 97.1 bits (240), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 123/461 (26%), Positives = 197/461 (42%), Gaps = 38/461 (8%) Query: 21 RAAQLGLSTAI---VEPK----YWG--GVCLNVGCIPSKALLRNAELVHIFTKDAKAFGI 71 AA+ G A+ VEP WG G C+NVGCIP K L+ A L+ +DA+ FG Sbjct: 131 EAAKYGAKIAVLDYVEPTPMGTTWGLGGTCVNVGCIPKK-LMHQAGLLSHSLEDAQHFGW 189 Query: 72 S---GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDG 128 S E++ D+ + + G ++ N +T ++ G + + + + Sbjct: 190 SLDKSEISHDWSTMVEGVQSHIGSLNWGYKVSLRDNAVTYLNARGMLLSPHEVQITEKNK 249 Query: 129 GTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEF 186 ++T + I+ATG + +PG +T ++ P ++ GA + ++ Sbjct: 250 KVSTITGNKIILATGERPKYPEIPGAIEYG--ITSDDLFSLPYFPGKTLVVGASYVALKC 307 Query: 187 GYVLKNYGVDVTIV--EFLPRALPNEDAD-VSKEIEK---QFKKLGV----TILTATKVE 236 L + G DVT++ L R + A+ V +E +F KL V T L E Sbjct: 308 AGFLASLGGDVTVMVRSILLRGFDQQMAEKVGDYMENHGVKFAKLCVPDEITQLKPVDTE 367 Query: 237 SIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY 296 + G V T DG E + E V+ A+G P + + GV L + D Sbjct: 368 NNKPGLLLVKGHYT-DGKKFEEEFETVIFAVGREPQLSKLNCEAVGVKLDKNGRVVCSDD 426 Query: 297 MRTNVGHIYAIGDVN-GLLQLAHVA-EAQGVVAAETIAGAETLTLGDHRMLPRATFCQPN 354 +T V +IYAIGD+N G QL VA A +A AGA LT D+ + F Sbjct: 427 EQTTVSNIYAIGDINAGKPQLTPVAIHAGRYLARRLFAGATELT--DYSNVATTVFTPLE 484 Query: 355 VASFGLTEQQA----RNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVAD-AKHGELLGG 409 + GL+E+ A + +V + F AH D ++KLV + + +LG Sbjct: 485 YGACGLSEEDAIEKYGDNDIEVYHSHFKPLEWTVAHR-EDNVCYMKLVCRISDNMRVLGL 543 Query: 410 HLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 H++G + E+ +A + T + R + HPT SE Sbjct: 544 HVLGPNAGEITQGYAVAIKMGATKEDFDRTIGIHPTCSETF 584 >4B1B-A nrPDB Length = 542 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 114/489 (23%), Positives = 205/489 (41%), Gaps = 48/489 (9%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAI---VEPK----YWG--GVCLNVGCIPSKALLR 54 YD VV+G GPGG +A AA G + V+P WG G C+NVGC+P K + Sbjct: 43 YDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMHY 102 Query: 55 NAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVA--EGRVAGVHFL----MKKNKITE 108 + IF D+KA+G FD + +D + V + + ++F ++ +K+ Sbjct: 103 AGHMGSIFKLDSKAYGWK----FD-NLKHDWKKLVTTVQSHIRSLNFSYMTGLRSSKVKY 157 Query: 109 IHGYGTFADANTLLVDLND--GGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQIL 166 I+G D NT+ L E+VT +IATG + + + + I Sbjct: 158 INGLAKLKDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELSITSDDIF 217 Query: 167 S-RELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKL 225 S ++ P ++ GA + +E L + G DVT V L D + +++ ++ Sbjct: 218 SLKKDPGKTLVVGASYVALECSGFLNSLGYDVT-VAVRSIVLRGFDQQCAVKVKLYMEEQ 276 Query: 226 GVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVAL 285 GV + + ++ V + EL + VL AIG +++G L+ + + Sbjct: 277 GVMFKNGILPKKLTKMDDKILVEFSDK--TSEL-YDTVLYAIGRKGDIDGLNLESLNMNV 333 Query: 286 TDRKAIGVDDYMR-TNVGHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGAETLTLGDHR 343 + D++ TN+ I+A+GDV + +LA VA G + A + ++ + D+ Sbjct: 334 NKSNNKIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRLF-KDSDEIMDYS 392 Query: 344 MLPRATFCQPNVASFGLTEQQAR----NEGYDVVVAKFPFTANAKAHGVG---------- 389 +P + + + G +E++A +V + +F + H Sbjct: 393 YIPTSIYTPIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAVHRQKHIRAQKDEYD 452 Query: 390 ---DPSGFVKLVA-DAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPT 445 + KLV + ++G H VG + E+ + LA R + + + HPT Sbjct: 453 LDVSSTCLAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALRLKVKKKDFDNCIGIHPT 512 Query: 446 MSEALQECF 454 +E+ F Sbjct: 513 DAESFMNLF 521 >5ER0-A nrPDB Length = 518 Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 88/341 (25%), Positives = 147/341 (43%), Gaps = 29/341 (8%) Query: 117 DANTLLV-DLNDGGTESVTFDNAIIATGSSTRL--VPG-----TSLSANVVTYEEQILSR 168 D T+ V DL + + ++D ++ +GS + +PG L N + I Sbjct: 135 DQKTVTVEDLTNHAQTTESYDKLVMTSGSWPIVPKIPGIDSDRVKLCKNWAHAQALIEDA 194 Query: 169 ELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNE-DADVSKEIEKQFKKLGV 227 + K I + GAG IG E G DVT+++ + R +P DAD + IE+ ++ GV Sbjct: 195 KEAKRITVIGAGYIGAELAEAYSTTGHDVTLIDAMARVMPKYFDADFTDVIEQDYRDHGV 254 Query: 228 TILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 + VES D + +T+ K+ +L + IGF PN + L K V + Sbjct: 255 QLALGETVESFTDSATGLTIKTDKNSYETDL----AILCIGFRPNTD---LLKGKVDMAP 307 Query: 288 RKAIGVDDYMRTNVGHIYAIGDV----------NGLLQLAHVAEAQGVVAAETIAGAETL 337 AI DDYMR++ I+A GD N + LA A QG++ + + Sbjct: 308 NGAIITDDYMRSSNPDIFAAGDSAAVHYNPTHQNAYIPLATNAVRQGILVGKNLVKPTVK 367 Query: 338 TLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKL 397 +G A + + + S GLT A+ +G + + +P + L Sbjct: 368 YMGTQSSSGLALYDR-TIVSTGLTLAAAKQQGLNAEQVIVEDNYRPEFMPSTEPV-LMSL 425 Query: 398 VADAKHGELLGGHLVG-HDVAELLPELTLAQRWDLTASELA 437 V D +LGG L+ +DV++ L++ + + T +LA Sbjct: 426 VFDPDTHRILGGALMSKYDVSQSANTLSVCIQNENTIDDLA 466 >3Q6J-A nrPDB Length = 523 Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 113/474 (23%), Positives = 191/474 (40%), Gaps = 64/474 (13%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIF 62 YD + +G G G + +G IV+ + GG C + C+P H+F Sbjct: 44 YDAIFIGGGAAGRFGSAYLRAMGGRQLIVDRWPFLGGSCPHNACVPH----------HLF 93 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 + A ++ + Y D + KV + F +N HG F L Sbjct: 94 SDCAAELMLARTFSGQYWFP-DMTEKVVGIKEVVDLFRAGRNGP---HGIMNFQSKEQLN 149 Query: 123 VD--LN-----------DGGTESVTFDNAIIATGSS--TRLVPGTSLSANVVTYEEQILS 167 ++ LN + + N I+A G+ T VPG + ++ L Sbjct: 150 LEYILNCPAKVIDNHTVEAAGKVFKAKNLILAVGAGPGTLDVPGVNAKG---VFDHATLV 206 Query: 168 RELP----KSIIIAGAGAIGMEFGYVLKNYGVD-VTIVEFLPRALPNEDADVSKEIEKQF 222 EL ++++ G +E+G G V +V P L +D + + + Sbjct: 207 EELDYEPGSTVVVVGGSKTAVEYGCFFNATGRRTVMLVRTEPLKLI-KDNETRAYVLDRM 265 Query: 223 KKLGVTILTA---TKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLD 279 K+ G+ I++ T++E A+G Q V +T +G E++ E +G L Sbjct: 266 KEQGMEIISGSNVTRIEEDANGRVQAVVAMTPNG---EMRIETDFVFLGLGEQPRSAELA 322 Query: 280 KA-GVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLT 338 K G+ L + + V++Y++T+V ++YA+GD+ G A G AA + G E ++ Sbjct: 323 KILGLDLGPKGEVLVNEYLQTSVPNVYAVGDLIGGPMEMFKARKSGCYAARNVMG-EKIS 381 Query: 339 LGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPF-TAN--------------- 382 + P V+ G+ E++AR G+++V K P T N Sbjct: 382 Y-TPKNYPDFLHTHYEVSFLGMGEEEARAAGHEIVTIKMPPDTENGLNVALPASDRTMLY 440 Query: 383 AKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASEL 436 A G SGF K+V DAK ++LG H VG+ + L + + LT EL Sbjct: 441 AFGKGTAHMSGFQKIVIDAKTRKVLGAHHVGYGAKDAFQYLNVLIKQGLTVDEL 494 >4FX9-A nrPDB Length = 453 Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 95/327 (29%), Positives = 147/327 (44%), Gaps = 44/327 (13%) Query: 126 NDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYE--------EQILSRELPKSII 175 +GG +S +D + A G+S ++ + G +L V T + + + + ++++ Sbjct: 97 ENGGEKSYEWDYLVFANGASPQVPAIEGVNLKG-VFTADLPPDALAIREYMEKYKVENVV 155 Query: 176 IAGAGAIGMEFGYVLKNYGVDVTIV----EFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 I G G IG+E G +VT++ L R+ E D+ +E K+ L + +T Sbjct: 156 IIGGGYIGIEMAEAFAAQGKNVTMIVRGERVLRRSFDKEVTDILEEKLKKHVNLRLQEIT 215 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAI 291 K+E G +V VT G E KAE V+ A G PN+E + GV + + AI Sbjct: 216 -MKIE----GEERVEKVVTDAG---EYKAELVILATGIKPNIEL--AKQLGVRIGETGAI 265 Query: 292 GVDDYMRTNVGHIYAIGDV----------NGLLQLAHVAEAQGVVAAETIAGAETLTLGD 341 ++ M+T+V ++YA GDV + LA G VA IAG E G Sbjct: 266 WTNEKMQTSVENVYAAGDVAETRHVITGRRVWVPLAPAGNKMGYVAGSNIAGKELHFPG- 324 Query: 342 HRMLPRAT--FCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVA 399 +L A F + GLTE +A EGYDV A F + + G ++K V Sbjct: 325 --VLGTAVTKFMDVEIGKTGLTEMEALKEGYDVRTA-FIKASTRPHYYPGGREIWLKGVV 381 Query: 400 DAKHGELLGGHLVGHDVAELLPELTLA 426 D + LLG +VG D+ LP + A Sbjct: 382 DNETNRLLGVQVVGSDI---LPRIDTA 405 >2BC1-A nrPDB Length = 490 Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 86/355 (24%), Positives = 147/355 (41%), Gaps = 45/355 (12%) Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLVP--GTSLSANVVTYEEQI--------- 165 DA T+ L DG T+D I ATGS L P G + + +E + Sbjct: 121 DAKTVTA-LVDGKNHVETYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLY 179 Query: 166 ---------LSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVS 215 L + K + + GAG IG+E + G +V +++ + L D D++ Sbjct: 180 QNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLT 239 Query: 216 KEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEG 275 + K ++ G+ + V+ +A G + K+ E + V+ A+GF PN Sbjct: 240 DLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKN----EYDVDMVILAVGFRPNTT- 294 Query: 276 YGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDV----------NGLLQLAHVAEAQGV 325 L + L A V+ T++ +YAIGD + LA A G+ Sbjct: 295 --LGNGKIDLFRNGAFLVNKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGI 352 Query: 326 VAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKA 385 VAA G + +G + + ++ S GLT ++A+ G+D V + +T N K Sbjct: 353 VAAHNACGTDLEGIGVQGSNGISIYGL-HMVSTGLTLEKAKRLGFDAAVTE--YTDNQKP 409 Query: 386 HGV--GDPSGFVKLVADAKHGELLGGHLVGH-DVAELLPELTLAQRWDLTASELA 437 + G+ +K+V D +LG + DV+ + +LA + +T +LA Sbjct: 410 EFIEHGNFPVTIKIVYDKDSRRILGAQMAAREDVSMGIHMFSLAIQEGVTIEKLA 464 >2CDU-A nrPDB Length = 452 Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 58/192 (30%), Positives = 97/192 (50%), Gaps = 16/192 (8%) Query: 126 NDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV----TYEE-QILSRELPK--SIIIAG 178 N+ TE+ +D I+ TGS + P + ++ V Y + + L E PK +I I G Sbjct: 99 NEEKTEA--YDKLIMTTGSKPTVPPIPGIDSSRVYLCKNYNDAKKLFEEAPKAKTITIIG 156 Query: 179 AGAIGMEFGYVLKNYGVDVTIVEFLPRALPNE-DADVSKEIEKQFKKLGVTILTATKVES 237 +G IG E N +V +++ R L D + + + K ++ GV ++ +KV + Sbjct: 157 SGYIGAELAEAYSNQNYNVNLIDGHERVLYKYFDKEFTDILAKDYEAHGVNLVLGSKVAA 216 Query: 238 IADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYM 297 + ++ +T T DG +E+K++ + IGF PN E L K VA+ D AI D+YM Sbjct: 217 FEEVDDEI-ITKTLDG--KEIKSDIAILCIGFRPNTE---LLKGKVAMLDNGAIITDEYM 270 Query: 298 RTNVGHIYAIGD 309 ++ I+A GD Sbjct: 271 HSSNRDIFAAGD 282 >3CGD-A nrPDB Length = 480 Score = 65.1 bits (157), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 79/308 (25%), Positives = 128/308 (41%), Gaps = 41/308 (13%) Query: 134 TFDNAIIATGSST-------RLVPGTSLSANVVTYEEQILSRELPK--SIIIAGAGAIGM 184 ++D +IATG R + G L + E + + E K + I G GAIG+ Sbjct: 140 SYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGL 199 Query: 185 EFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQ 244 E G V ++E D D+++ I K+ K + ILT V++ G + Sbjct: 200 EMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHHIEILTNENVKAFK-GNER 258 Query: 245 VTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHI 304 V T G KA+ VL ++G PN + L+ + + AI V+ YM+TNV + Sbjct: 259 VEAVETDKGT---YKADLVLVSVGVKPNTDF--LEGTNIRTNHKGAIEVNAYMQTNVQDV 313 Query: 305 YAIGD----------VNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRAT----- 349 YA GD ++ + + A QG +A L + D R + T Sbjct: 314 YAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAG--------LNMLDKRRAFKGTLGTGI 365 Query: 350 --FCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELL 407 F +A GL E++A+ K T A + P ++KL+ + +LL Sbjct: 366 IKFMNLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPL-YLKLLYRSDTKQLL 424 Query: 408 GGHLVGHD 415 GG ++G + Sbjct: 425 GGQVIGEE 432 >3ICS-A nrPDB Length = 588 Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 76/289 (26%), Positives = 132/289 (45%), Gaps = 44/289 (15%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL 230 P+ + G G IG+E L+ G++VT+VE + +P D +++ + + K V ++ Sbjct: 187 PRHATVIGGGFIGVEMVENLRERGIEVTLVEMANQVMPPIDYEMAAYVHEHMKNHDVELV 246 Query: 231 TATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKA 290 V+++ + G+ V + K G ++ + ++ AIG P E AG+AL R Sbjct: 247 FEDGVDALEENGAVVRL---KSGSV--IQTDMLILAIGVQP--ESSLAKGAGLALGVRGT 299 Query: 291 IGVDDYMRTNVGHIYAIGD----------VNGLLQLAHVAEAQGVVAAETIAG-AETL-- 337 I V++ +T+ HIYAIGD ++ LA A QG + A+ I G ++L Sbjct: 300 IKVNEKFQTSDPHIYAIGDAIEVKDFVTETETMIPLAWPANRQGRMLADIIHGHTDSLYK 359 Query: 338 -TLGDHRMLPRATFCQPNVASFGLTEQ--QARNEGYDVVVAKFPFTANAKAHGVGDPSG- 393 TLG A VA+ GL E+ + N Y+VV A +H P+ Sbjct: 360 GTLGTS----VAKVFDLTVATTGLNEKILKRLNIPYEVV------HVQANSHAGYYPNAT 409 Query: 394 --FVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNV 440 +KL+ + G++ G +G D + +R D+ A+ + N+ Sbjct: 410 PVLIKLIFNKDSGKIYGAQTLGRDGVD--------KRMDVIATAIKANL 450 >3IWA-A nrPDB Length = 472 Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 74/272 (27%), Positives = 117/272 (43%), Gaps = 29/272 (10%) Query: 124 DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVT----------YEEQILSRELPKS 173 +L G ++ +D ++A GS P + VT + I + E+ K+ Sbjct: 103 NLRTGERRTLKYDKLVLALGSKANRPPVEGMDLAGVTPVTNLDEAEFVQHAISAGEVSKA 162 Query: 174 IIIAGAGAIGMEFGYVLKN-YGVDVTIVEFLPRALPN-EDADVSKEIEKQFKKLGVTILT 231 +I+ G G IG+E L + +G+D T+VE + +P +S+ + +K V + T Sbjct: 163 VIVGG-GFIGLEMAVSLADMWGIDTTVVELADQIMPGFTSKSLSQMLRHDLEKNDVVVHT 221 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAI 291 KV + +V +T + L A+ V+ A G +PN + D AG+ L R AI Sbjct: 222 GEKVVRLEGENGKVARVITD---KRTLDADLVILAAGVSPNTQ-LARD-AGLELDPRGAI 276 Query: 292 GVDDYMRTNVGHIYAIGDV----------NGLLQLAHVAEAQGVVAAETIAGAETLTLGD 341 VD MRT+ I+A GD G L +A QG V +A + G Sbjct: 277 IVDTRMRTSDPDIFAGGDCVTIPNLVTGKPGFFPLGSMANRQGRVIGTNLADGDATFPGA 336 Query: 342 HRMLPRATFCQPNVASFGLTEQQARNEGYDVV 373 F + + + GLT + A EGYD V Sbjct: 337 VGSWAVKLF-EGSASGAGLTVEGALREGYDAV 367 >3FG2-P nrPDB Length = 404 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 56/189 (29%), Positives = 89/189 (47%), Gaps = 20/189 (10%) Query: 132 SVTFDNAIIATGSSTRLVPGTSLSANVVTY-----EEQILSRELP--KSIIIAGAGAIGM 184 ++ + + ++ATG+ R++ + S V Y E ++L + +P K +++ GAG IG+ Sbjct: 96 AIEYGHLVLATGARNRMLDVPNASLPDVLYLRTLDESEVLRQRMPDKKHVVVIGAGFIGL 155 Query: 185 EFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKL----GVTILTATKVESIAD 240 EF + G++V +VE PR + V+ EI F G+ + + IA Sbjct: 156 EFAATARAKGLEVDVVELAPRVMARV---VTPEISSYFHDRHSGAGIRMHYGVRATEIAA 212 Query: 241 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN 300 G +VT V DG L + V+ +G PNVE A L I VD + T+ Sbjct: 213 EGDRVTGVVLSDG--NTLPCDLVVVGVGVIPNVE----IAAAAGLPTAAGIIVDQQLLTS 266 Query: 301 VGHIYAIGD 309 HI AIGD Sbjct: 267 DPHISAIGD 275 >3LXD-A nrPDB Length = 415 Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 62/197 (31%), Positives = 96/197 (48%), Gaps = 17/197 (8%) Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVP--GTSLSA--NVVTYEE-QILSREL---PKSI 174 V L DG ++ + I ATG R + G L+ V T E+ L EL K+ Sbjct: 98 VKLGDG--SAIEYGKLIWATGGDPRRLSCVGADLAGVHAVRTKEDADRLMAELDAGAKNA 155 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEI-EKQFKKLGVTILTAT 233 ++ G G IG+E VL +GV+VT++E LPR L + E + + + GV + T Sbjct: 156 VVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVAGEALSEFYQAEHRAHGVDLRTGA 215 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 ++ I G++VT +DG + A+ V+ IG P V L AG + + V Sbjct: 216 AMDCIEGDGTKVTGVRMQDGSV--IPADIVIVGIGIVPCVG--ALISAGA--SGGNGVDV 269 Query: 294 DDYMRTNVGHIYAIGDV 310 D++ RT++ +YAIGD Sbjct: 270 DEFCRTSLTDVYAIGDC 286 >4GCM-A nrPDB Length = 312 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 88/343 (25%), Positives = 136/343 (39%), Gaps = 61/343 (17%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLN---VGCIPSKALLRNAELVH 60 +D+ ++GAGP G AA+ A++ L T ++E GG N V P ++ +L Sbjct: 7 FDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLST 66 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 + AK FG + YG I + G + N Sbjct: 67 KMFEHAKKFG----AVYQYG------------------------DIKSVEDKGEYKVINF 98 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRL--VPG-TSLSANVVTYEEQILSRELP-KSIII 176 G + +T IIATG+ + VPG L V+Y K + + Sbjct: 99 --------GNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFV 150 Query: 177 AGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEI--EKQFKKLGVTILTATK 234 G G +E G L + VTIV D ++ I ++ FK + + + Sbjct: 151 IGGGDSAVEEGTFLTKFADKVTIVH-------RRDELRAQRILQDRAFKNDKIDFIWSHT 203 Query: 235 VESIADGGSQV---TVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAI 291 ++SI + +V T+T TKDG + +A+ V IG P + G+ D I Sbjct: 204 LKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPF--KDLGIT-NDVGYI 260 Query: 292 GVDDYMRTNVGHIYAIGDV--NGLLQLAHVAEAQGVVAAETIA 332 D M T+V I+A GDV GL Q+ A G +AA++ A Sbjct: 261 VTKDDMTTSVPGIFAAGDVRDKGLRQIV-TATGDGSIAAQSAA 302 >2Q7V-A nrPDB Length = 325 Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 81/336 (24%), Positives = 123/336 (36%), Gaps = 72/336 (21%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY------WGGVCLNVGCIPSKALLRNAE 57 YDVV++G GP G AAI + LST I+E W N P + E Sbjct: 9 YDVVIIGGGPAGLTAAIYTGRAQLSTLILEKGMPGGQIAWSEEVENFPGFPEP--IAGME 66 Query: 58 LVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFAD 117 L + A+ FG E+ G+ +D + V G + + + Sbjct: 67 LAQRMHQQAEKFGAKVEMDEVQGVQHDATSHPYPFTVRGYNGEYRAKAV----------- 115 Query: 118 ANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPG----------TSLSANVVTYEEQI 165 I+ATG+ R +PG T + + Y+ Sbjct: 116 ---------------------ILATGADPRKLGIPGEDNFWGKGVSTCATCDGFFYKG-- 152 Query: 166 LSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKL 225 K +++ G G +E G L + +VT++ N+ A + F Sbjct: 153 ------KKVVVIGGGDAAVEEGMFLTKFADEVTVIHRRDTLRANKVAQA-----RAFANP 201 Query: 226 GVTILTATKVESI--ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGV 283 + + T VE I AD S V + K G EL + V IG PN K V Sbjct: 202 KMKFIWDTAVEEIQGADSVSGVKLRNLKTGEVSELATDGVFIFIGHVPNT---AFVKDTV 258 Query: 284 ALTDRKAIGVDDYMRTNVGHIYAIGDVNGLL--QLA 317 +L D + V D + TN+ ++A GDV+ + QLA Sbjct: 259 SLRDDGYVDVRDEIYTNIPMLFAAGDVSDYIYRQLA 294 >2YVG-A nrPDB Length = 408 Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 60/204 (29%), Positives = 96/204 (47%), Gaps = 23/204 (11%) Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLVP---GTSLSANVV-TYEE--QILSREL 170 D V L+DG T + + ++ATG++ R +P G ++ + + T E+ +I + Sbjct: 86 DPQAHTVALSDGRT--LPYGTLVLATGAAPRALPTLQGATMPVHTLRTLEDARRIQAGLR 143 Query: 171 PKS-IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVSKEIEKQFKKLGVT 228 P+S ++I G G IG+E + GV V++VE PR + A ++ + + GV Sbjct: 144 PQSRLLIVGGGVIGLELAATARTAGVHVSLVETQPRLMSRAAPATLADFVARYHAAQGVD 203 Query: 229 ILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDK-AGVALTD 287 + V DG V + DG + A+ V+ IG N L + AG+A D Sbjct: 204 LRFERSVTGSVDG-----VVLLDDGT--RIAADMVVVGIGVLAN---DALARAAGLACDD 253 Query: 288 RKAIGVDDYMRTNVGHIYAIGDVN 311 I VD Y RT +YA+GDV Sbjct: 254 --GIFVDAYGRTTCPDVYALGDVT 275 >5MIU-A nrPDB Length = 535 Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 45/178 (25%), Positives = 87/178 (48%), Gaps = 29/178 (16%) Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLVP-----GTSLSANVVTYEE-------Q 164 D +V LNDG +TF+ +IATG + R + G + + + + + Sbjct: 159 DVRGNMVKLNDGS--QITFEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRALE 216 Query: 165 ILSRELPKSIIIAGAGAIGMEFGYVL--KNYGVDVTIVEFLP------RALPNEDADVSK 216 +SRE+ KSI + G G +G E L K+ + +++ P + LP ++ + Sbjct: 217 KISREV-KSITVIGEGFLGSELACALGRKSQASGIEVIQLFPEKGNMGKILPQYLSNWTM 275 Query: 217 EIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVE 274 E + K+ GV ++ V+S+ G ++ + + KDG ++++ + ++ A+G PNVE Sbjct: 276 E---KVKREGVKVMPNAIVQSVGVSGGRLLIKL-KDG--RKVETDHIVTAVGLEPNVE 327 >1NHQ-A nrPDB Length = 447 Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 68/291 (23%), Positives = 118/291 (40%), Gaps = 49/291 (16%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRAL-PNEDADVSKEIEKQFKKLGVTILT 231 ++++ G+G IG+E G VT+++ L R L D + + + ++ + +TI T Sbjct: 151 NVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDRPLGVYLDKEFTDVLTEEMEANNITIAT 210 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAI 291 VE G V K+ +L V+ A+G PN K + L I Sbjct: 211 GETVERYEGDGRVQKVVTDKNAYDADL----VVVAVGVRPNTAWL---KGTLELHPNGLI 263 Query: 292 GVDDYMRTNVGHIYAIGDVNGL----------LQLAHVAEAQGVVAAET----------I 331 D+YMRT+ ++A+GD + + LA A QG A + + Sbjct: 264 KTDEYMRTSEPDVFAVGDATLIKYNPADTEVNIALATNARKQGRFAVKNLEEPVKPFPGV 323 Query: 332 AGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYD----VVVAKFPFTANAKAHG 387 G+ L + D++ AS G+ E A+ G + VV + N Sbjct: 324 QGSSGLAVFDYKF-----------ASTGINEVMAQKLGKETKAVTVVEDYLMDFNPDKQ- 371 Query: 388 VGDPSGFVKLVADAKHGELLGGHLVGH-DVAELLPELTLAQRWDLTASELA 437 + KLV D + ++LG L+ D+ + ++LA + +T +LA Sbjct: 372 ----KAWFKLVYDPETTQILGAQLMSKADLTANINAISLAIQAKMTIEDLA 418 >1Q1R-A nrPDB Length = 431 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 55/200 (27%), Positives = 92/200 (46%), Gaps = 21/200 (10%) Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVP---GTSLSANVVTY-----EEQILSREL--PK 172 V L+DG ++ +D ++ATG R +P G AN Y + + + R+L Sbjct: 93 VILSDG--RALDYDRLVLATGGRPRPLPVASGAVGKANNFRYLRTLEDAECIRRQLIADN 150 Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDA-DVSKEIEKQFKKLGVTILT 231 +++ G G IG+E + VT+++ R L A VS E ++ GV I T Sbjct: 151 RLVVIGGGYIGLEVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDIRT 210 Query: 232 ATKVE--SIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRK 289 T+V ++ +VT + +DG L A+ V+ IG PN E + L Sbjct: 211 GTQVCGFEMSTDQQKVTAVLCEDGT--RLPADLVIAGIGLIPNCEL----ASAAGLQVDN 264 Query: 290 AIGVDDYMRTNVGHIYAIGD 309 I ++++M+T+ I A+GD Sbjct: 265 GIVINEHMQTSDPLIMAVGD 284 >3NTA-A nrPDB Length = 574 Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 82/353 (23%), Positives = 147/353 (41%), Gaps = 50/353 (14%) Query: 125 LNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYE-------EQILSRELPKSI--- 174 L DG ++D +++ G++ +VP N +T+ ++IL ++ Sbjct: 96 LLDGSEYQESYDTLLLSPGAAP-IVPPIPGVDNPLTHSLRNIPDMDRILQTIQMNNVEHA 154 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATK 234 + G G IG+E L + G+ T++E + + D +++ + + GV + T Sbjct: 155 TVVGGGFIGLEMMESLHHLGIKTTLLELADQVMTPVDREMAGFAHQAIRDQGVDLRLGTA 214 Query: 235 VESIADGGSQVTVTVTKDGVAQE-------------------LKAEKVLQAIGFAPNVEG 275 + ++ QV V D ++ L+ + ++ AIG P E Sbjct: 215 LSEVS---YQVQTHVASDAAGEDTAHQHIKGHLSLTLSNGELLETDLLIMAIGVRP--ET 269 Query: 276 YGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGD-------VNG---LLQLAHVAEAQGV 325 AG+A+ + I V+ M+T+ IYA+GD V G L+ LA A QG Sbjct: 270 QLARDAGLAIGELGGIKVNAMMQTSDPAIYAVGDAVEEQDFVTGQACLVPLAGPANRQGR 329 Query: 326 VAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAK-FPFTANAK 384 +AA+ + G E G F V + G E+Q + G + K + TA+ Sbjct: 330 MAADNMFGREERYQGTQGTAICKVF-DLAVGATGKNEKQLKQAG--IAFEKVYVHTASHA 386 Query: 385 AHGVGDPSGFVKLVADAKHGELLGGHLVGHD-VAELLPELTLAQRWDLTASEL 436 ++ G KL+ D G + G VG D + + + + +AQR +T +L Sbjct: 387 SYYPGAEVVSFKLLFDPVKGTIFGAQAVGKDGIDKRIDVMAVAQRAGMTVEQL 439 >5JCN-A nrPDB Length = 451 Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 70/229 (30%), Positives = 104/229 (45%), Gaps = 30/229 (13%) Query: 132 SVTFDNAIIATGSSTRLVP--GT--SLSANVVTYEEQILSRELPKSI--------IIAGA 179 + T++ IIATGSS + GT + S N++ E + +L +I +I G Sbjct: 129 TFTYEILIIATGSSVIKLSDFGTQGADSNNILYLREVDDADKLVAAIQAKKGGKAVIVGG 188 Query: 180 GAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVSKEIEKQFKKLGVTILTAT-KVES 237 G IG+E LK DVT+V P +P AD++ E + GV I+ T V Sbjct: 189 GYIGLELSAALKINDFDVTMVFPEPWCMPRLFTADIAAFYESYYTNKGVKIVKGTVAVGF 248 Query: 238 IADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYM 297 AD VT K+G L+A+ V+ +G P L K VA ++ I D + Sbjct: 249 DADANGDVTAVNLKNGSV--LEADIVVVGVGGRPLTT---LFKGQVA-EEKGGIKTDAFF 302 Query: 298 RTNVGHIYAIGDV--------NGLLQLAHVAEAQGVV--AAETIAGAET 336 T+V +YA+GDV N L ++ HV A+ A + I G E+ Sbjct: 303 ETSVPGVYAVGDVATFPMKMYNELRRVEHVDHARKSAEQAVKAIKGKES 351 >1YQZ-A nrPDB Length = 438 Score = 47.8 bits (112), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 63/285 (22%), Positives = 121/285 (42%), Gaps = 23/285 (8%) Query: 163 EQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQF 222 +Q + +++ GAG + +E L G+ T++ + DAD+++ I + Sbjct: 140 DQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDEL 199 Query: 223 KKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAG 282 K + ++ +I G+++T K G + + +++ +G PN + ++ + Sbjct: 200 DKREIPYRLNEEINAI--NGNEITF---KSGKVEHY--DMIIEGVGTHPNSKF--IESSN 250 Query: 283 VALTDRKAIGVDDYMRTNVGHIYAIGDV----------NGLLQLAHVAEAQGVVAAETIA 332 + L + I V+D TNV +IYAIGD+ + LA A + AE IA Sbjct: 251 IKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIA 310 Query: 333 GAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPS 392 G +T+ F AS G+ + + Y +V AN + G+ Sbjct: 311 GNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHAN---YYPGNSP 367 Query: 393 GFVKLVADAKHGELLGGHLVGHDVAE-LLPELTLAQRWDLTASEL 436 +++ D + ++L VG + A+ + L++A LT EL Sbjct: 368 LHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDEL 412 >5MJK-A nrPDB Length = 327 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 81/326 (24%), Positives = 130/326 (39%), Gaps = 70/326 (21%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCI---PSKALLRNAELVH 60 YDVV++G+GP G AA+ A+ + T ++E GG N I P + EL Sbjct: 25 YDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMGPELSM 84 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 + + G+ F GI E HG D Sbjct: 85 KMAEPLEGLGVENAYGFVTGI--------------------------EDHG-----DYKK 113 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTS-LSANVVTYE---EQILSRELPKSI 174 ++ + ++ T+S+ IIATG++ R +PG A V+Y + R + I Sbjct: 114 IITEDDEFITKSI-----IIATGANHRKLEIPGEEEYGARGVSYCAVCDGAFFRN--QEI 166 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQ--FKKLGVTILTA 232 ++ G G +E L +G VTI + D ++EI +Q FK+ + + Sbjct: 167 LVIGGGDSAVEEALYLTRFGQSVTI-------MHRRDKLRAQEIIQQRAFKEEKINFIWD 219 Query: 233 TKVESIADGGSQVTVTVTKD---GVAQELKAEKVLQAIGFAPNVE---GYGL-DKAGVAL 285 + I ++ V K+ G E + +G P E G+ D+AG + Sbjct: 220 SVPMEIKGDDKKIQSVVYKNVKTGEVTEKAFGGIFIYVGLDPVAEFVSDLGITDEAGWII 279 Query: 286 TDRKAIGVDDYMRTNVGHIYAIGDVN 311 TD D+MRTN+ I+A+GDV Sbjct: 280 TD-------DHMRTNIPGIFAVGDVR 298 >5KVH-A nrPDB Length = 543 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 43/178 (24%), Positives = 85/178 (47%), Gaps = 29/178 (16%) Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLVP-----GTSLSANVVTYEE-------Q 164 D +V LNDG +T++ +IATG + R + G + + + + + Sbjct: 161 DVRDNMVKLNDGS--QITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLE 218 Query: 165 ILSRELPKSIIIAGAGAIGMEFGYVL--KNYGVDVTIVEFLP------RALPNEDADVSK 216 +SRE+ KSI I G G +G E L K + +++ P + LP ++ + Sbjct: 219 KISREV-KSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTM 277 Query: 217 EIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVE 274 E + ++ GV ++ V+S+ ++ + + KDG ++++ + ++ A+G PNVE Sbjct: 278 E---KVRREGVKVMPNAIVQSVGVSSGKLLIKL-KDG--RKVETDHIVAAVGLEPNVE 329 >4EMJ-A nrPDB Length = 410 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 63/208 (30%), Positives = 92/208 (44%), Gaps = 23/208 (11%) Query: 114 TFADANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVV--TYEEQILSRE 169 T D T + L+DG T S D +IATGS R +PG+ L V TY + + R+ Sbjct: 81 TALDVQTRTISLDDGTTLSA--DAIVIATGSRARTMALPGSQLPGVVTLRTYGDVQVLRD 138 Query: 170 LPKS---IIIAGAGAIGMEFGYVLKNYGVDVTIV----EFLPRALPNEDADVSKEIEKQF 222 S ++I G G IG E + G+ VTI+ E L R L + + Sbjct: 139 SWTSATRLLIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRVLGRR---IGAWLRGLL 195 Query: 223 KKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAG 282 +LGV + T V + G Q+ + DG + A+ L +G P + +AG Sbjct: 196 TELGVQVELGTGVVGFS-GEGQLEQVMASDG--RSFVADSALICVGAEPADQLA--RQAG 250 Query: 283 VALTDRKAIGVDDYMRTNVGHIYAIGDV 310 +A DR I VD T ++A+GDV Sbjct: 251 LA-CDRGVI-VDHCGATLAKGVFAVGDV 276 >5UTH-A nrPDB Length = 319 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 80/325 (24%), Positives = 128/325 (39%), Gaps = 65/325 (20%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61 T +DV+++G+GP GY AAI AA+ L + E +GG + + + R Sbjct: 14 TVHDVIIIGSGPAGYTAAIYAARAQLKPLVFEGTQFGGALMTTTEVENYPGFRE------ 67 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTL 121 GI+G D + + G M+ ++ G T+ Sbjct: 68 --------GITGPELMD--------QMREQALRFGADLRMEDVDAVQLEG-----PVKTV 106 Query: 122 LVDLNDGGTESVTFDNAIIATGSSTRL--VPG----TSLSANVVTYEEQILSRELPKSII 175 +V G E+ I+A G++ R VPG T + + + R+ + I+ Sbjct: 107 VV-----GDETHQARAVILAMGAAARHLGVPGEEALTGMGVSTCATCDGFFFRD--QDIV 159 Query: 176 IAGAGAIGMEFGYVLKNYGVDVTIV----EFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 + G G ME L + VT++ EF + E A +++I T LT Sbjct: 160 VVGGGDSAMEEATFLTRFARSVTLIHRRDEFRASKIMLERARANEKI---------TFLT 210 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQE---LKAEKVLQAIGFAPNVEGYGLDKAGVALTDR 288 T++ I +G +VT +D V E L V AIG P E L + V L D Sbjct: 211 NTEITQI-EGDPKVTGVRLRDTVTGEESKLDVTGVFVAIGHDPRSE---LVRGQVELDDE 266 Query: 289 ---KAIGVDDYMRTNVGHIYAIGDV 310 K G Y T++ ++A GD+ Sbjct: 267 GYVKVQGRTTY--TSLDGVFAAGDL 289 >5UWY-A nrPDB Length = 308 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 84/336 (25%), Positives = 129/336 (38%), Gaps = 92/336 (27%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 YD +++G+GP G AA+ AA+ LS AI+E GG N Sbjct: 5 YDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNN-------------------- 44 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHG----YGTFADAN 119 F I +D+ + + K+ E ++K + I+G F D Sbjct: 45 ----TFDIENYPGYDHISGPELAMKMYEP--------LEKFNVENIYGIVQKIENFGDYK 92 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRL--VPG----TSLSANVVTYEEQILSRELPKS 173 +L + D E+ T IIATG+ R+ VPG TS + + R+ + Sbjct: 93 CVLTE--DASYEAKT---VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRD--QD 145 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVE----------FLPRALPNEDAD-----VSKEI 218 +++ G G +E L + VT+V RA N+ D V KEI Sbjct: 146 LLVVGGGDSAVEEAIYLTQFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEI 205 Query: 219 EKQFKKLGVTILTATKVESIAD---GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEG 275 + K+ ++ K + D GG V +G P V G Sbjct: 206 QGNDIKVSNVLIENVKTGQVTDHAFGG--------------------VFIYVGMNP-VTG 244 Query: 276 YGLDKAGVALTDRKA-IGVDDYMRTNVGHIYAIGDV 310 D + +TD + I DD+MRT++ I+AIGDV Sbjct: 245 MVKD---LEITDSEGWIITDDHMRTSIPGIFAIGDV 277 >3OC4-A nrPDB Length = 452 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 51/187 (27%), Positives = 89/187 (47%), Gaps = 21/187 (11%) Query: 134 TFDNAIIATGSS--TRLVPGTSLSANVVTYEEQILS--------RELPKSIIIAGAGAIG 183 ++D I+ATG+S + + G S + ++ Y + LS E +++ + GAG IG Sbjct: 103 SYDKLILATGASQFSTQIRG-SQTEKLLKY--KFLSGALAAVPLLENSQTVAVIGAGPIG 159 Query: 184 MEFGYVLKNYGVDVTIVEFLPRALPNE-DADVSKEIEKQFKKLGVTILTATKVESIADGG 242 ME L V + E L LP D ++ E++K +K V V I + Sbjct: 160 MEAIDFLVKMKKTVHVFESLENLLPKYFDKEMVAEVQKSLEKQAVIFHFEETVLGIEETA 219 Query: 243 SQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVG 302 + + + ++ QE+ + + A+ P + Y LDK D + I VD Y++T+V Sbjct: 220 NGIVLETSE----QEISCDSGIFALNLHPQL-AY-LDKKIQRNLD-QTIAVDAYLQTSVP 272 Query: 303 HIYAIGD 309 +++AIGD Sbjct: 273 NVFAIGD 279 >3KLJ-A nrPDB Length = 385 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 62/254 (24%), Positives = 109/254 (42%), Gaps = 39/254 (15%) Query: 99 FLMKKNKITEIHG-------YGTFADANTLLVDLNDGGTESVTFDNAIIATGS--STRLV 149 L+KKN E + + T D N LV L G E + ++ IIA+GS + V Sbjct: 64 ILIKKNDWYEKNNIKVITSEFATSIDPNNKLVTLKSG--EKIKYEKLIIASGSIANKIKV 121 Query: 150 PGTSLSANVVTYEEQILSRELPKS---IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 P ++ +Y++ + ++ K+ I G G +G+E + + G +I L Sbjct: 122 PHADEIFSLYSYDDALKIKDECKNKGKAFIIGGGILGIELAQAIIDSGTPASIGIILEYP 181 Query: 207 LPNE-DADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQ 265 L + D D ++ + +LG+ I T + E + D +++ V+ Sbjct: 182 LERQLDRDGGLFLKDKLDRLGIKIYTNSNFEEMGD----------------LIRSSCVIT 225 Query: 266 AIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLL----QLAHVAE 321 A+G PN++ + ++ I V+D+M T++ IYA GDV L ++A Sbjct: 226 AVGVKPNLDFI----KDTEIASKRGILVNDHMETSIKDIYACGDVAEFYGKNPGLINIAN 281 Query: 322 AQGVVAAETIAGAE 335 QG VA G + Sbjct: 282 KQGEVAGLNACGED 295 >2V3B-A nrPDB Length = 384 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 56/220 (25%), Positives = 103/220 (46%), Gaps = 25/220 (11%) Query: 129 GTESVTFDNAIIATGSSTRLVP--GTSLSA--NVVTYEEQILSREL---PKSIIIAGAGA 181 G E V + + ++A G+ VP G + A + E+ R+ + +++ GAG Sbjct: 96 GEEEVRYRDLVLAWGAEPIRVPVEGDAQDALYPINDLEDYARFRQAAAGKRRVLLLGAGL 155 Query: 182 IGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVSKEIEKQFKKLGVTILTATKVESIAD 240 IG EF L + G + +V + +P +K ++ + LGV + S+ Sbjct: 156 IGCEFANDLSSGGYQLDVVAPCEQVMPGLLHPAAAKAVQAGLEGLGVRFHLGPVLASLKK 215 Query: 241 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVE-GYGLDKAGVALTDRKAIGVDDYMRT 299 G + ++ DG + + + V+ A+G P E + AG+A+ + I VD +RT Sbjct: 216 AGEGLEAHLS-DG--EVIPCDLVVSAVGLRPRTELAFA---AGLAVN--RGIVVDRSLRT 267 Query: 300 NVGHIYAIGD------VNGLLQLAHVAEAQGVVAAETIAG 333 + +IYA+GD +N L + +A A+ + A+T+AG Sbjct: 268 SHANIYALGDCAEVDGLNLLYVMPLMACARAL--AQTLAG 305 >6BWT-A nrPDB Length = 319 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 80/337 (23%), Positives = 124/337 (36%), Gaps = 84/337 (24%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG---VCLNVGCIPSKAL-LRNAEL 58 H+ +++LG+GP GY AAI AA+ L I+ GG +V P + + EL Sbjct: 7 HHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVYNWPGEPDGIMGPEL 66 Query: 59 VHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADA 118 + K A+ FD I YD + V K K+ Sbjct: 67 MEKLQKQAE--------RFDTQIVYD--------TINAVDLQNKPFKLV----------- 99 Query: 119 NTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELP------- 171 G E T D IIATG++ + + S EE+ + + + Sbjct: 100 ---------GEVEQYTCDTLIIATGATAKYLGLES--------EEKFMGKGVSACATCDG 142 Query: 172 -----KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEK-QFKKL 225 K + + G G +E L N VT++ L +E + K +EK Q + Sbjct: 143 FFYKNKDVAVVGGGNTAVEEALFLSNIAKSVTLIH-RRDTLRSEKILIDKLMEKAQHGNI 201 Query: 226 GVTILTATKVESIAD--GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNV---------- 273 + I T E + D G + + + K ++ V AIG PN Sbjct: 202 NI-IWNTTLEEVLGDDMGVNALRIKNIKTNEESQMGVAGVFIAIGHTPNTSIFAGQLEME 260 Query: 274 EGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDV 310 GY K+G+A D +TN+ ++A GDV Sbjct: 261 NGYIKVKSGLA---------GDATQTNIKGVFAAGDV 288 >5XHU-A nrPDB Length = 329 Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 75/323 (23%), Positives = 127/323 (39%), Gaps = 60/323 (18%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE--PKYWGGVCL--------NVGCIPSKALL 53 YDV ++G GP G A L T ++E PK G V L ++G IP A Sbjct: 3 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPEKIIRDIGGIPGIA-- 60 Query: 54 RNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYG 113 +L+ + A TFD I ++ RV G L I G Sbjct: 61 -GKQLIEQLKEQA--------ATFDPDIVLNQ-------RVTGFERL-DDGTIVLTGSEG 103 Query: 114 TFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKS 173 T+++ G E FD+ A + L Y + L K Sbjct: 104 KKHYTRTVILACGMGTLEVNEFDSEDAARYAGKNL-----------HYGVEKLDAFKGKR 152 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 ++I+G G +++ L+ VT+V ++ V+K K+ V +LT Sbjct: 153 VVISGGGDTAVDWANELEPIAASVTVVH-RREEFGGMESSVTK-----MKQSSVRVLTPY 206 Query: 234 KVESI---ADGGSQVTVTVTKDGVAQELKAEKVLQAIGF----APNVEGYGLDKAGVALT 286 ++E + +G VTV T+ G ++++ ++++ GF P +E +GL+ Sbjct: 207 RLEQLNGDEEGIKSVTVCHTESGQRKDIEIDELIINHGFKIDLGPMME-WGLE------I 259 Query: 287 DRKAIGVDDYMRTNVGHIYAIGD 309 + + D +MRTN+ ++ GD Sbjct: 260 EEGRVKADRHMRTNLPGVFVAGD 282 >3F8P-A nrPDB Length = 323 Score = 41.6 bits (96), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 84/343 (24%), Positives = 135/343 (39%), Gaps = 61/343 (17%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALL---RNAELV 59 +DV+++G GP Y AA+ +A+ L T ++ + GG G + L + ++++ Sbjct: 15 KFDVIIVGLGPAAYGAALYSARYMLKTLVI-GETPGGQLTEAGIVDDYLGLIEIQASDMI 73 Query: 60 HIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADAN 119 +F K + + + + D K+ E R G F++K + E Sbjct: 74 KVFNKHIEKYEVP--------VLLDIVEKI-ENR--GDEFVVKTKRKGEFKA-------- 114 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILSRELPKSIIIA 177 D+ I+ G R VPG A + L K+ ++A Sbjct: 115 ----------------DSVILGIGVKRRKLGVPGEQEFAGRGISYCSVCDAPLFKNRVVA 158 Query: 178 --GAGAIGMEFGYVLKNYGVDVTIVEFLP--RALPNEDADVSKEIEKQFKKLGVTILTAT 233 G G +E +L +Y V ++ +A P V K+ +F +L + Sbjct: 159 VIGGGDSALEGAEILSSYSTKVYLIHRRDTFKAQPIYVETVKKKPNVEF------VLNSV 212 Query: 234 KVESIADGG-SQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKA-I 291 E D QV V K G +EL V IGF P + K+ TD I Sbjct: 213 VKEIKGDKVVKQVVVENLKTGEIKELNVNGVFIEIGFDPPTD---FAKSNGIETDTNGYI 269 Query: 292 GVDDYMRTNVGHIYAIGDVN----GLLQLAHVAEAQGVVAAET 330 VD++MRT+V ++A GD G Q+ A AQG VAA + Sbjct: 270 KVDEWMRTSVPGVFAAGDCTSAWLGFRQVI-TAVAQGAVAATS 311 >5U63-A nrPDB Length = 321 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 69/294 (23%), Positives = 114/294 (38%), Gaps = 67/294 (22%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKA----LLRNA 56 + H +++LG+GP GY AAI AA+ L +V GG I + + + Sbjct: 7 IKHAKLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTDEIENWPGDFEMTTGS 66 Query: 57 ELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFA 116 L+ + A+ F E+ FD+ D S + + F Sbjct: 67 GLMQRMLQHAEKF--ETEIVFDHINRVDLSSRP----------------------FKLFG 102 Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLV--------PGTSLSANVVTYEEQILSR 168 D ++ T D IIATG+S R + G +SA + R Sbjct: 103 D------------VQNFTCDALIIATGASARYIGLPSEENYKGRGVSACATC--DGFFYR 148 Query: 169 ELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEI--EKQFKKL- 225 P +I G G +E L N V ++ D+ +++I ++ +KK+ Sbjct: 149 NKPVGVI--GGGNTAVEEALYLANIASTVHLIH-------RRDSFRAEKILIDRLYKKVE 199 Query: 226 -GVTILTATKV--ESIAD--GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVE 274 G +L + E + D G + + + TK G +ELK + + AIG +PN E Sbjct: 200 EGKIVLHTDRTLDEVLGDNMGVTGLRLANTKTGEKEELKLDGLFVAIGHSPNTE 253 >5W4C-A nrPDB Length = 371 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 87/329 (26%), Positives = 132/329 (40%), Gaps = 60/329 (18%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 H VV++G+GPGG+ AAI A+ L EP + G+ N G P L Sbjct: 30 HSKVVIIGSGPGGHTAAIYLARANL-----EPVLYEGMLAN-GFAPGGQLTT-------- 75 Query: 63 TKDAKAF-----GISGEVTFDYGIAYDRS--RKVAEGRVAGVHFLMKKNKITEIHGYGTF 115 T D + F G++G D A K+ VA V ++ K Y T Sbjct: 76 TTDVENFPGFPEGVTGTEMMDKFRAQSERFGTKIITETVARVDLSVRPFK------YWTE 129 Query: 116 ADANTLLVDLNDGGTESVTFDNAIIATGSSTR--LVPG------TSLSANVVTYEEQILS 167 + +T D I+ATG+S + +PG + +SA V + Sbjct: 130 GEEEEHEF---------MTADTIILATGASAKRLFLPGEETYWQSGISACAVCDGAVPIF 180 Query: 168 RELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKK-LG 226 R+ P ++I G G E L YG V ++ + ++ SK + K+ Sbjct: 181 RQKPLAVI--GGGDSAAEEATYLTKYGSHVYVL------VRRDELRASKIMAKRLTSHPK 232 Query: 227 VTILTAT-KVESIADGG--SQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGV 283 VT+L T E+ DG + +T+ TK G +L + AIG P L K+ V Sbjct: 233 VTVLWNTVATEAKGDGEVLTSLTIKNTKTGETGDLPVNGLFYAIGHEPATS---LVKSQV 289 Query: 284 AL-TDRKAIGVDDYMRTNVGHIYAIGDVN 311 L +D V +T+V ++A GDV Sbjct: 290 ELDSDGYIKTVPGTSQTSVHGVFAAGDVQ 318 >5NA1-A nrPDB Length = 408 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 65/278 (23%), Positives = 103/278 (37%), Gaps = 54/278 (19%) Query: 97 VHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSA 156 V ++KK+K+ + T D + V+ N G + FD ++A G + + Sbjct: 73 VESVLKKDKVNFVQAEVTKIDRDAKKVETNQGIYD---FDILVVALGFVSETFGIEGMKD 129 Query: 157 NVVTYEEQILSRELPK--------------------SIIIAGAGAIGMEF--------GY 188 + E I +REL + SI++ GAG G+EF Sbjct: 130 HAFQIENVITARELSRHIEDKFANYAASKEKDDNDLSILVGGAGFTGVEFLGELTDRIPE 189 Query: 189 VLKNYGVD-----VTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGS 243 + YGVD +T VE P+ LP ++ + GV AT + + + G Sbjct: 190 LCSKYGVDQNKVKITCVEAAPKMLPMFSEELVNHAVSYLEDRGVEFKIATPIVACNEKGF 249 Query: 244 QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDR-KAIGVDDYMRTNVG 302 V V DG Q+L A + A G V G L + R + + D Sbjct: 250 VVEV----DGEKQQLNAGTSVWAAG----VRGSKLMEESFEGVKRGRIVTKQDLTINGYD 301 Query: 303 HIYAIGDVNGLL---------QLAHVAEAQGVVAAETI 331 +I+ IGD + + A +A QG A+ I Sbjct: 302 NIFVIGDCSAFIPAGEERPLPTTAQIAMQQGESVAKNI 339 >2A87-A nrPDB Length = 335 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 4/70 (5%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNA----ELVH 60 DV+V+G+GP GY AA+ AA+ L+ + E +GG + + + RN EL+ Sbjct: 16 DVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNGITGPELMD 75 Query: 61 IFTKDAKAFG 70 + A FG Sbjct: 76 EMREQALRFG 85 >2ZBW-A nrPDB Length = 335 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 74/315 (23%), Positives = 123/315 (39%), Gaps = 38/315 (12%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 H DV+++GAGP G A GLS V+P G L P K + A ++ Sbjct: 5 HTDVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPEPGGQLT-ALYPEKYIYDVAGFPKVY 63 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 KD + F+ V+ L ++ + E G + Sbjct: 64 AKDLVKGLVEQVAPFN-----------------PVYSLGERAETLEREG-------DLFK 99 Query: 123 VDLNDGGTESVTFDNAIIATG----SSTRL-VPG-TSLSANVVTYEEQILSRELPKSIII 176 V + G + T IIA G R+ PG V Y + + K ++I Sbjct: 100 VTTSQG--NAYTAKAVIIAAGVGAFEPRRIGAPGEREFEGRGVYYAVKSKAEFQGKRVLI 157 Query: 177 AGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVE 236 G G +++ L + +T++ P+ +E + KE+ K ++ + +LT ++ Sbjct: 158 VGGGDSAVDWALNLLDTARRITLIHRRPQFRAHEAS--VKELMKAHEEGRLEVLTPYELR 215 Query: 237 SIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYG-LDKAGVALTDRKAIGVDD 295 + +G +V V QE A +V + A + G L G+AL K I VD Sbjct: 216 RV-EGDERVRWAVVFHNQTQEELALEVDAVLILAGYITKLGPLANWGLALEKNK-IKVDT 273 Query: 296 YMRTNVGHIYAIGDV 310 M T++ +YA GD+ Sbjct: 274 TMATSIPGVYACGDI 288 >4ZN0-A nrPDB Length = 311 Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 9/94 (9%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG------VCLNVGCIPSKALLRN 55 + YD++++G GP G A I A + GL T I+E G + N PS + Sbjct: 6 SMYDLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISGQISMADIVENYPGFPS---ISG 62 Query: 56 AELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKV 89 EL+ F A+ G+ +T + + ++K+ Sbjct: 63 LELMERFRTHAQEVGVKTTITEVLSVRSEGTKKI 96 >3AB1-A nrPDB Length = 360 Score = 35.8 bits (81), Expect = 0.042, Method: Compositional matrix adjust. Identities = 37/145 (25%), Positives = 67/145 (46%), Gaps = 15/145 (10%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIV----EFLPRALPNEDADVSKEIEKQFKKLGV 227 K ++I G G +++ L VT+V EF + E+E+ + Sbjct: 164 KRVVIVGGGDSALDWTVGLIKNAASVTLVHRGHEF------QGHGKTAHEVERARANGTI 217 Query: 228 TILTATKVESIADGGSQVTVT--VTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVAL 285 + T+V SI + +T + DG ++A+++L IGF N+ L + + L Sbjct: 218 DVYLETEVASIEESNGVLTRVHLRSSDGSKWTVEADRLLILIGFKSNLGP--LARWDLEL 275 Query: 286 TDRKAIGVDDYMRTNVGHIYAIGDV 310 + A+ VD +M+T+V +YA GD+ Sbjct: 276 YE-NALVVDSHMKTSVDGLYAAGDI 299 >5USX-A nrPDB Length = 319 Score = 35.4 bits (80), Expect = 0.057, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 24/39 (61%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG 39 M H +++LG+GP GY AA+ AA+ L+ ++ GG Sbjct: 4 MKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMQQGG 42 >1NAA-A nrPDB Length = 541 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 22/32 (68%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 T YD +++GAGPGG +AA R ++ G ++E Sbjct: 1 TPYDYIIVGAGPGGIIAADRLSEAGKKVLLLE 32 >3RHA-A nrPDB Length = 482 Score = 33.1 bits (74), Expect = 0.29, Method: Compositional matrix adjust. Identities = 15/31 (48%), Positives = 21/31 (67%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK 35 DVV++GAGP G AA + GLS A++E + Sbjct: 9 DVVIVGAGPSGLTAARELKKAGLSVAVLEAR 39 >1F6M-A nrPDB Length = 320 Score = 32.3 bits (72), Expect = 0.50, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 22/37 (59%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG 39 H +++LG+GP GY AA+ AA+ L ++ GG Sbjct: 5 HSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGG 41 >4JNQ-A nrPDB Length = 345 Score = 32.0 bits (71), Expect = 0.52, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 20/30 (66%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIV 32 H V+V+G+GP GY AAI AA+ L ++ Sbjct: 26 HAPVIVIGSGPAGYTAAIYAARAMLKPVVI 55 >3BHF-A nrPDB Length = 390 Score = 31.6 bits (70), Expect = 0.68, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 22/32 (68%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 TH+DV+V+GAG G A + A+ G+ T +V+ Sbjct: 3 THFDVIVVGAGSMGMAAGYQLAKQGVKTLLVD 34 >3NIX-A nrPDB Length = 421 Score = 31.6 bits (70), Expect = 0.83, Method: Compositional matrix adjust. Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 4/47 (8%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVE----PKYWGGVCLNVGCI 47 DV+V+GAGP G VAA + G IVE P++ G L C+ Sbjct: 7 DVLVIGAGPAGTVAASLVNKSGFKVKIVEKQKFPRFVIGESLLPRCM 53 >6HA8-c nrPDB Length = 218 Score = 31.6 bits (70), Expect = 0.85, Method: Compositional matrix adjust. Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 3/51 (5%) Query: 196 DVTIVEFLPRALPNEDADVSK-EIEKQFKKLGVTILTATKVESIADGGSQV 245 D+ I E++ + L DA VSK EIE+ ++ +TI TA I GGS+V Sbjct: 35 DLKIREYISKRLS--DASVSKVEIERAANRVNITIHTAKPGMVIGKGGSEV 83 >3COX-A nrPDB Length = 507 Score = 31.2 bits (69), Expect = 0.91, Method: Compositional matrix adjust. Identities = 15/27 (55%), Positives = 20/27 (74%) Query: 7 VVLGAGPGGYVAAIRAAQLGLSTAIVE 33 +V+G+G GG VAA+R Q G+ T IVE Sbjct: 15 LVIGSGYGGAVAALRLTQAGIPTQIVE 41 >1REO-A nrPDB Length = 486 Score = 31.2 bits (69), Expect = 0.98, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 21/36 (58%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 PK +++ GAG G+ YVL G VT++E RA Sbjct: 33 PKHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASERA 68 >2HJH-A nrPDB Length = 354 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 13/122 (10%) Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKK--LGVTILTA 232 + A G++ Y+L +YGV + F ALPN+ K I + + L + I T+ Sbjct: 209 VAASQGSMSERPPYILNSYGVLKPDITFFGEALPNK---FHKSIREDILECDLLICIGTS 265 Query: 233 TKVESIADGGSQVT-----VTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 KV +++ + V V + +D V AE L +G+ ++ K G + Sbjct: 266 LKVAPVSEIVNMVPSHVPQVLINRDPVKH---AEFDLSLLGYCDDIAAMVAQKCGWTIPH 322 Query: 288 RK 289 +K Sbjct: 323 KK 324 >3KVE-A nrPDB Length = 486 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 21/36 (58%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 PK +++ GAG G+ YVL G VT++E RA Sbjct: 33 PKHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASERA 68 >3KRZ-A nrPDB Length = 337 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 4/63 (6%) Query: 314 LQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQ---PNVASFGLTEQQARNEGY 370 +QLAH A + ++ E + G + GD LPR + V +FG ++A GY Sbjct: 99 IQLAH-AGRKCNISYEDVVGPSPIKAGDRYKLPRELSVEEIKSIVKAFGEAAKRANLAGY 157 Query: 371 DVV 373 DVV Sbjct: 158 DVV 160 >2EW2-A nrPDB Length = 316 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 20/32 (62%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP 204 I IAGAGA+G G +L G DVT+++ P Sbjct: 5 KIAIAGAGAMGSRLGIMLHQGGNDVTLIDQWP 36 >1ZOV-A nrPDB Length = 386 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 21/32 (65%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 TH+DV+V+GAG G A A+ G+ T +V+ Sbjct: 2 THFDVIVVGAGSMGMAAGYYLAKQGVKTLLVD 33 Score = 28.1 bits (61), Expect = 8.6, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVE 201 +I+ GAG++GM GY L GV +V+ Sbjct: 6 VIVVGAGSMGMAAGYYLAKQGVKTLLVD 33 >1XHC-A nrPDB Length = 367 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 13/70 (18%) Query: 266 AIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGV 325 AIG PNV+ L + T R I +DD RT+ +YAIGD AE G+ Sbjct: 229 AIGIVPNVD---LARRSGIHTGR-GILIDDNFRTSAKDVYAIGD---------CAEYSGI 275 Query: 326 VAAETIAGAE 335 +A A E Sbjct: 276 IAGTAKAAME 285 >1F8S-A nrPDB Length = 498 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 19/31 (61%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVE 201 PK ++I GAG G+ YVL G VT++E Sbjct: 33 PKHVVIVGAGMAGLSAAYVLAGAGHQVTVLE 63 >4IAO-A nrPDB Length = 492 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 13/122 (10%) Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKK--LGVTILTA 232 + A G++ Y+L +YGV + F ALPN+ K I + + L + I T+ Sbjct: 347 VAASQGSMSERPPYILNSYGVLKPDITFFGEALPNK---FHKSIREDILECDLLICIGTS 403 Query: 233 TKVESIADGGSQVT-----VTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 KV +++ + V V + +D V AE L +G+ ++ K G + Sbjct: 404 LKVAPVSEIVNMVPSHVPQVLINRDPVKH---AEFDLSLLGYCDDIAAMVAQKCGWTIPH 460 Query: 288 RK 289 +K Sbjct: 461 KK 462 >5YGQ-A nrPDB Length = 342 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 43/167 (25%), Positives = 66/167 (39%), Gaps = 18/167 (10%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 K I+I G G +++ L +T+V R A S E +Q G L Sbjct: 155 KDILIVGGGDSALDWTLNLNPIAKSMTLVH---RRDDFRGAPHSVEQMRQLVASGKLDLK 211 Query: 232 ATKVESIADGGSQVTVTVTK--DGVAQELKAEKVLQAIGFAPN---VEGYGLDKAGVALT 286 ++ + Q+T K D ++K + +L G V +GLD Sbjct: 212 IGQITELQGDNGQLTGATVKLNDNTTSQIKCDAMLPFFGLTMKLGPVANWGLD------L 265 Query: 287 DRKAIGVDD-YMRTNVGHIYAIGDVN---GLLQLAHVAEAQGVVAAE 329 + I VD TNV I+AIGD+N G L+L +G + A+ Sbjct: 266 ENNLIPVDTGTFETNVPGIFAIGDINTYPGKLKLILSGFHEGALMAQ 312 >3ATQ-A nrPDB Length = 453 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 22/37 (59%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGV 40 YDV+++G G G AA + ++ GL +V+ K W + Sbjct: 7 YDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRI 43 >2QA2-A nrPDB Length = 499 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 21/33 (63%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPR 205 S+I+ GAG G+ L+ GVDV ++E LP+ Sbjct: 14 SVIVVGAGPAGLMLAGELRLGGVDVMVLEQLPQ 46 >6BPY-A nrPDB Length = 374 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 56/224 (25%), Positives = 83/224 (37%), Gaps = 62/224 (27%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNV----GCIPSKALLRN- 55 M H VV++G+GP + AAI LS A ++P + G+ N G + + + N Sbjct: 2 MVHTKVVIIGSGPAAHTAAIY-----LSRAELKPVLYEGMLANGTAAGGQLTTTTDIENF 56 Query: 56 ---------AELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKI 106 AEL+ K + FG +V ++ V K K Sbjct: 57 PGFPDGIGGAELMENMRKQSIRFGT----------------EVITETISRVDLSSKPFK- 99 Query: 107 TEIHGYGTFADANTLLVDLNDGGTE--SVTFDNAIIATGSSTRLV--PG------TSLSA 156 L + NDG + + T D IIATG++ R + PG +SA Sbjct: 100 --------------LWTEWNDGPDKEPACTADAVIIATGANARRLNLPGEETYWQNGISA 145 Query: 157 NVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIV 200 V + R P +I G G E L YG VT++ Sbjct: 146 CAVCDGAVPIFRNKPLYVI--GGGDSAAEEAMFLAKYGSSVTVL 187 >3IHM-A nrPDB Length = 430 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 18/30 (60%) Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTI 199 + K I I GAG G+ G L+ + VDVT+ Sbjct: 21 MKKRIGIVGAGTAGLHLGLFLRQHDVDVTV 50 >2GMH-A nrPDB Length = 584 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 13/21 (61%), Positives = 15/21 (71%) Query: 5 DVVVLGAGPGGYVAAIRAAQL 25 DVV++GAGP G AA R QL Sbjct: 37 DVVIVGAGPAGLSAATRLKQL 57 >5BR7-A nrPDB Length = 393 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 1/36 (2%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAA-QLGLSTAIVEPK 35 M+ +D++V+G+G G A RAA QLG IVE + Sbjct: 1 MSDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKR 36 >1VDC-A nrPDB Length = 333 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 48/178 (26%), Positives = 66/178 (37%), Gaps = 43/178 (24%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVE----------FLPRALPNEDADVSKEIEKQ 221 K + + G G ME L YG V I+ RAL N DV Sbjct: 160 KPLAVIGGGDSAMEEANFLTKYGSKVYIIHRRDAFRASKIMQQRALSNPKIDV------- 212 Query: 222 FKKLGVTILTATKVESIAD------GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVE- 274 I ++ VE+ D GG +V VT D +LK + AIG P + Sbjct: 213 -------IWNSSVVEAYGDGERDVLGGLKVKNVVTGD--VSDLKVSGLFFAIGHEPATKF 263 Query: 275 ---GYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDV-NGLLQLAHVAEAQGVVAA 328 G LD G +T +T+V ++A GDV + + A A G +AA Sbjct: 264 LDGGVELDSDGYVVTKPGT------TQTSVPGVFAAGDVQDKKYRQAITAAGTGCMAA 315 >3WFI-A nrPDB Length = 312 Score = 28.1 bits (61), Expect = 7.6, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 19/29 (65%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVE 201 I IAGAGA+G FG +L G +V +++ Sbjct: 2 KIAIAGAGAMGSRFGLMLHQSGNEVLLID 30 >6CR0-A nrPDB Length = 440 Score = 28.1 bits (61), Expect = 8.2, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 20/33 (60%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY 36 YD +V+GAG G VAA + G S I+E ++ Sbjct: 9 YDAIVVGAGFSGLVAARELSAQGRSVLIIEARH 41 >2D1C-A nrPDB Length = 496 Score = 28.1 bits (61), Expect = 8.2, Method: Compositional matrix adjust. Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 19/109 (17%) Query: 22 AAQLGLSTAIVE------PKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGEV 75 +A +G AI E PKY G +N P+ LL ++ + A A I + Sbjct: 266 SANIGNEVAIFEAVHGSAPKYAGKNVIN----PTAVLLSAVMMLRYLEEFATADLIENAL 321 Query: 76 --TFDYG-------IAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTF 115 T + G + YDR K E A + L K + T++ GY F Sbjct: 322 LYTLEEGRVLTGDVVGYDRGAKTTEYTEAIIQNLGKTPRKTQVRGYKPF 370 >4YKF-A nrPDB Length = 521 Score = 28.1 bits (61), Expect = 8.7, Method: Compositional matrix adjust. Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 11/141 (7%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 K + + G G G+E L VT++EF P ++ V ++ + K + + IL Sbjct: 356 KRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKADQ---VLQDKLRSLKNVDI-ILN 411 Query: 232 ATKVESIADGGSQVTVTVTKDGVA---QELKAEKVLQAIGFAPNVEGYGLDKAGVALTDR 288 A E D GS+V +D V+ ++ + IG PN + V Sbjct: 412 AQTTEVKGD-GSKVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWL---EGAVERNRM 467 Query: 289 KAIGVDDYMRTNVGHIYAIGD 309 I +D TNV ++A GD Sbjct: 468 GEIIIDAKCETNVKGVFAAGD 488 >5L3D-A nrPDB Length = 852 Score = 28.1 bits (61), Expect = 8.8, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 20/28 (71%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVE 201 +II G+G G+ L+++G+DVT++E Sbjct: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLE 308 >4CBQ-A nrPDB Length = 314 Score = 28.1 bits (61), Expect = 9.0, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 21/37 (56%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGV 40 +DVV++G+GP + AAI + L + E GGV Sbjct: 5 HDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGV 41 >2BRY-A nrPDB Length = 497 Score = 28.1 bits (61), Expect = 9.1, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 20/34 (58%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK 35 T+ +V+GAGP G AA+ A LG +VE + Sbjct: 91 TNTKCLVVGAGPCGLRAAVELALLGARVVLVEKR 124 >5KXJ-A nrPDB Length = 557 Score = 27.7 bits (60), Expect = 9.9, Method: Compositional matrix adjust. Identities = 12/19 (63%), Positives = 16/19 (84%) Query: 293 VDDYMRTNVGHIYAIGDVN 311 VDDY RT+V +YAIG+V+ Sbjct: 359 VDDYGRTDVDGLYAIGEVS 377 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3II4-A nrPDB 559 e-160 5U8W-A nrPDB 499 e-142 5TR3-A nrPDB 491 e-139 6N7F-A nrPDB 489 e-138 3LAD-A nrPDB 486 e-138 5J5Z-A nrPDB 485 e-137 3URH-A nrPDB 482 e-136 6BZ0-A nrPDB 477 e-135 5VDN-A nrPDB 474 e-134 1GEU-A nrPDB 474 e-134 1EBD-A nrPDB 473 e-134 1DXL-A nrPDB 472 e-133 2YQU-A nrPDB 464 e-131 1V59-A nrPDB 463 e-131 2R9Z-A nrPDB 463 e-131 2QAE-A nrPDB 461 e-130 6AON-A nrPDB 461 e-130 5U1O-A nrPDB 460 e-130 2EQ6-A nrPDB 459 e-129 6B4O-A nrPDB 458 e-129 6DU7-A nrPDB 454 e-128 5V36-A nrPDB 453 e-128 2HQM-A nrPDB 450 e-127 2AAQ-A nrPDB 448 e-126 1ZDL-A nrPDB 445 e-125 6CMZ-A nrPDB 443 e-124 4JDR-A nrPDB 440 e-124 2X8H-A nrPDB 438 e-123 4LA1-A nrPDB 434 e-122 1LVL-A nrPDB 433 e-122 2YAU-A nrPDB 433 e-121 2WOV-A nrPDB 430 e-121 1FEC-A nrPDB 427 e-120 3O0H-A nrPDB 426 e-119 4KPR-E nrPDB 426 e-119 5X1Y-B nrPDB 424 e-119 2CFY-A nrPDB 420 e-118 4NEW-A nrPDB 419 e-117 5W1J-A nrPDB 414 e-116 4B1B-A nrPDB 410 e-115 2NVK-X nrPDB 409 e-114 1ONF-A nrPDB 398 e-111 4DNA-A nrPDB 393 e-110 4YWO-A nrPDB 381 e-106 1ZK7-A nrPDB 366 e-101 1OJT-A nrPDB 366 e-101 5U25-A nrPDB 362 e-100 3IC9-A nrPDB 330 8e-91 1XDI-A nrPDB 321 5e-88 3L8K-A nrPDB 312 2e-85 3Q6J-A nrPDB 269 2e-72 5ER0-A nrPDB 227 7e-60 2BC1-A nrPDB 227 9e-60 3CGD-A nrPDB 217 8e-57 3ICS-A nrPDB 213 2e-55 3NTA-A nrPDB 211 6e-55 1NHQ-A nrPDB 210 9e-55 1YQZ-A nrPDB 200 1e-51 3IWA-A nrPDB 199 2e-51 2CDU-A nrPDB 198 5e-51 4FX9-A nrPDB 192 2e-49 4GCM-A nrPDB 189 2e-48 5MJK-A nrPDB 186 1e-47 2Q7V-A nrPDB 184 8e-47 5UWY-A nrPDB 183 1e-46 3OC4-A nrPDB 176 2e-44 3F8P-A nrPDB 173 2e-43 5UTH-A nrPDB 167 1e-41 6BWT-A nrPDB 164 7e-41 5XHU-A nrPDB 153 2e-37 1Q1R-A nrPDB 142 3e-34 3LXD-A nrPDB 139 3e-33 3FG2-P nrPDB 137 9e-33 5JCN-A nrPDB 136 2e-32 2V3B-A nrPDB 133 1e-31 3KLJ-A nrPDB 128 7e-30 2YVG-A nrPDB 127 1e-29 4EMJ-A nrPDB 114 1e-25 5KVH-A nrPDB 111 6e-25 5MIU-A nrPDB 108 5e-24 Sequences not found previously or not previously below threshold: 2A87-A nrPDB 155 4e-38 4ZN0-A nrPDB 152 3e-37 5U63-A nrPDB 151 7e-37 1F6M-A nrPDB 149 3e-36 5USX-A nrPDB 142 2e-34 5W4C-A nrPDB 141 6e-34 4CBQ-A nrPDB 131 5e-31 6BPY-A nrPDB 129 2e-30 3D8X-A nrPDB 124 8e-29 2ZBW-A nrPDB 121 9e-28 3ISH-A nrPDB 120 1e-27 3R9U-A nrPDB 116 2e-26 4JNQ-A nrPDB 115 3e-26 3AB1-A nrPDB 115 4e-26 5M5J-A nrPDB 115 6e-26 1VDC-A nrPDB 113 2e-25 5JFC-L nrPDB 112 3e-25 1XHC-A nrPDB 109 3e-24 6GAR-A nrPDB 109 4e-24 3LZX-A nrPDB 108 5e-24 4YKF-A nrPDB 108 7e-24 4YRY-B nrPDB 103 2e-22 1FL2-A nrPDB 103 2e-22 2WHD-A nrPDB 100 1e-21 6GAS-A nrPDB 99 2e-21 5YGQ-A nrPDB 99 4e-21 5VJ7-A nrPDB 98 7e-21 5TWC-A nrPDB 93 2e-19 2VDC-G nrPDB 81 8e-16 4G74-A nrPDB 79 4e-15 5NA1-A nrPDB 77 1e-14 5JWC-A nrPDB 71 9e-13 3H8L-A nrPDB 63 3e-10 1PS9-A nrPDB 62 4e-10 4NTC-A nrPDB 62 7e-10 4FK1-A nrPDB 60 3e-09 2TMD-A nrPDB 55 6e-08 2CVJ-A nrPDB 54 2e-07 3UP5-A nrPDB 53 2e-07 5J7X-A nrPDB 52 4e-07 1NAA-A nrPDB 52 6e-07 3HYW-A nrPDB 51 8e-07 5NMX-A nrPDB 51 9e-07 4C5O-A nrPDB 51 1e-06 4USR-A nrPDB 51 1e-06 4OVI-A nrPDB 50 2e-06 4TLZ-A nrPDB 50 3e-06 5BR7-A nrPDB 47 2e-05 1ZOV-A nrPDB 47 2e-05 5KXJ-A nrPDB 47 2e-05 3K30-A nrPDB 46 4e-05 3T14-A nrPDB 46 4e-05 1Y56-A nrPDB 45 6e-05 3BHF-A nrPDB 45 7e-05 2UZZ-A nrPDB 45 9e-05 3KVE-A nrPDB 45 1e-04 6A37-A nrPDB 45 1e-04 1REO-A nrPDB 44 1e-04 3ATQ-A nrPDB 44 1e-04 4DGK-A nrPDB 43 2e-04 4Y4M-A nrPDB 43 3e-04 2VOU-A nrPDB 43 3e-04 1F8S-A nrPDB 43 3e-04 2JB2-A nrPDB 43 3e-04 6JDK-A nrPDB 43 3e-04 3RHA-A nrPDB 43 4e-04 1I8T-A nrPDB 42 4e-04 4B68-A nrPDB 42 5e-04 2GMH-A nrPDB 42 5e-04 3NIX-A nrPDB 42 6e-04 4Y4N-A nrPDB 42 6e-04 2BXR-A nrPDB 42 6e-04 1O5W-A nrPDB 41 7e-04 3MJ4-A nrPDB 41 8e-04 2GAG-A nrPDB 41 0.001 5EQD-A nrPDB 41 0.001 6CR0-A nrPDB 41 0.001 3ABT-A nrPDB 41 0.002 5L3D-A nrPDB 40 0.002 1QO8-A nrPDB 40 0.002 1KNR-A nrPDB 40 0.002 4C3X-A nrPDB 40 0.002 2BRY-A nrPDB 40 0.003 3WE0-A nrPDB 40 0.003 4TXK-A nrPDB 40 0.003 6HNS-A nrPDB 40 0.003 2VVL-G nrPDB 39 0.004 1F14-A nrPDB 39 0.005 3NK2-X nrPDB 39 0.006 2VHY-A nrPDB 38 0.006 4A6N-B nrPDB 38 0.007 3IHG-A nrPDB 38 0.007 4AP1-A nrPDB 38 0.007 6C6P-A nrPDB 38 0.008 2XVH-A nrPDB 38 0.008 5CQF-A nrPDB 38 0.008 1C0L-A nrPDB 38 0.008 6BRD-A nrPDB 38 0.008 4MOP-A nrPDB 38 0.008 2E5V-A nrPDB 38 0.008 3S61-A nrPDB 38 0.009 3HDH-A nrPDB 38 0.009 2ZXH-A nrPDB 38 0.012 1SEZ-A nrPDB 37 0.016 4K2X-A nrPDB 37 0.021 2GAG-B nrPDB 36 0.025 4MO2-B nrPDB 36 0.028 4UDQ-A nrPDB 36 0.030 3G5Q-A nrPDB 36 0.034 3CP8-A nrPDB 36 0.037 6ER9-A nrPDB 36 0.043 3KYB-A nrPDB 36 0.047 1X14-A nrPDB 36 0.047 5MOG-A nrPDB 35 0.052 6HRD-A nrPDB 35 0.053 4H7U-A nrPDB 35 0.067 4Z2R-A nrPDB 35 0.073 3UKH-A nrPDB 35 0.074 5AYV-A nrPDB 35 0.075 1FOH-A nrPDB 35 0.076 3COX-A nrPDB 35 0.078 6ACQ-A nrPDB 35 0.085 2Y0D-A nrPDB 34 0.095 6H3G-A nrPDB 34 0.096 5EZ7-A nrPDB 34 0.100 3Q9T-A nrPDB 34 0.11 1GPE-A nrPDB 34 0.12 5XGV-A nrPDB 34 0.12 1VRQ-A nrPDB 34 0.12 4A7P-A nrPDB 34 0.12 3F3S-A nrPDB 34 0.14 1RP0-A nrPDB 34 0.15 5KOX-A nrPDB 34 0.16 4MIF-A nrPDB 34 0.16 3BI4-A nrPDB 34 0.18 3FPZ-A nrPDB 34 0.20 6MO6-A nrPDB 33 0.21 4YNU-A nrPDB 33 0.22 3ADO-A nrPDB 33 0.22 5X6R-A nrPDB 33 0.24 2QA2-A nrPDB 33 0.25 3OZ2-A nrPDB 33 0.29 6J0Z-C nrPDB 33 0.30 4RG3-A nrPDB 33 0.30 5L46-A nrPDB 33 0.31 3GG2-A nrPDB 33 0.32 5I68-A nrPDB 33 0.33 2DKH-A nrPDB 33 0.35 4RPJ-A nrPDB 33 0.41 5EB4-A nrPDB 33 0.43 4Z25-A nrPDB 33 0.43 4U2L-A nrPDB 32 0.48 4IV9-A nrPDB 32 0.49 4N9X-A nrPDB 32 0.52 1LQU-A nrPDB 32 0.52 5X68-A nrPDB 32 0.56 2BS2-A nrPDB 32 0.56 3IHM-A nrPDB 32 0.57 5TUF-A nrPDB 32 0.58 1GDH-A nrPDB 32 0.59 1J49-A nrPDB 32 0.60 5XMJ-A nrPDB 32 0.65 4IIN-A nrPDB 31 0.82 4K22-A nrPDB 31 0.82 4B4O-A nrPDB 31 0.88 3CP2-A nrPDB 31 0.92 4HA6-A nrPDB 31 0.96 2WTB-A nrPDB 31 0.96 3G05-A nrPDB 31 1.00 2BKW-A nrPDB 31 1.0 6DLL-A nrPDB 31 1.0 4P9S-A nrPDB 31 1.0 3KKJ-A nrPDB 31 1.0 4KUG-A nrPDB 31 1.1 4XRR-A nrPDB 31 1.1 1E3J-A nrPDB 31 1.1 4EIQ-A nrPDB 31 1.2 4ZCC-A nrPDB 31 1.2 4Z44-A nrPDB 31 1.2 3HN2-A nrPDB 31 1.3 1QU3-A nrPDB 31 1.3 3RED-A nrPDB 31 1.3 6IUM-B nrPDB 31 1.3 1LTX-R nrPDB 31 1.3 3LOV-A nrPDB 31 1.3 2RGJ-A nrPDB 31 1.4 4FSH-A nrPDB 31 1.5 4FQ8-A nrPDB 31 1.5 1XFD-A nrPDB 31 1.6 5Y77-A nrPDB 30 1.7 5NCC-A nrPDB 30 1.7 3BA1-A nrPDB 30 1.9 5TUM-A nrPDB 30 2.0 3JSK-A nrPDB 30 2.0 2EEZ-A nrPDB 30 2.1 3GDN-A nrPDB 30 2.1 1OCX-A nrPDB 30 2.3 1FW8-A nrPDB 30 2.3 2B76-A nrPDB 30 2.4 4JA9-A nrPDB 30 2.4 1QPG-A nrPDB 30 2.4 4REP-A nrPDB 30 2.5 4D3F-A nrPDB 30 2.5 4R16-A nrPDB 30 2.8 3I6D-A nrPDB 30 2.8 2IVE-A nrPDB 30 2.8 2JFH-A nrPDB 29 2.9 2CUL-A nrPDB 29 2.9 3I83-A nrPDB 29 3.2 1KYQ-A nrPDB 29 3.2 5JBN-A nrPDB 29 3.2 3RP7-A nrPDB 29 3.3 2ZJ1-A nrPDB 29 3.3 5U4H-A nrPDB 29 3.4 1PJ5-A nrPDB 29 3.5 3KYD-B nrPDB 29 3.5 1XJ5-A nrPDB 29 3.7 1A17-A nrPDB 29 3.7 3KYC-B nrPDB 29 3.7 4PRK-A nrPDB 29 3.8 3AOE-E nrPDB 29 3.9 4X4J-A nrPDB 29 4.4 2EW2-A nrPDB 29 4.4 3SM8-A nrPDB 29 4.5 4NV4-A nrPDB 29 4.7 2QK4-A nrPDB 29 5.1 4G65-A nrPDB 29 5.2 6F73-A nrPDB 29 5.6 5YL7-A nrPDB 29 5.6 4UEJ-A nrPDB 29 5.7 3LLV-A nrPDB 29 5.7 2X3N-A nrPDB 29 5.9 3QY6-A nrPDB 29 6.0 3HM2-A nrPDB 29 6.1 4CJX-A nrPDB 29 6.1 1YOV-B nrPDB 29 6.2 1UIR-A nrPDB 28 6.4 2CDC-A nrPDB 28 6.6 3E2V-A nrPDB 28 6.7 2NVU-B nrPDB 28 7.0 6APH-A nrPDB 28 7.3 3OJO-A nrPDB 28 7.8 1M9N-A nrPDB 28 9.8 >3II4-A nrPDB Length = 466 Score = 559 bits (1441), Expect = e-160, Method: Composition-based stats. Identities = 464/464 (100%), Positives = 464/464 (100%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH 60 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH Sbjct: 3 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH 62 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT Sbjct: 63 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 122 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG 180 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG Sbjct: 123 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG 182 Query: 181 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD 240 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD Sbjct: 183 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD 242 Query: 241 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN 300 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN Sbjct: 243 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN 302 Query: 301 VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL 360 VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL Sbjct: 303 VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL 362 Query: 361 TEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELL 420 TEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELL Sbjct: 363 TEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELL 422 Query: 421 PELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 PELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF Sbjct: 423 PELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 466 >5U8W-A nrPDB Length = 481 Score = 499 bits (1286), Expect = e-142, Method: Composition-based stats. Identities = 174/471 (36%), Positives = 252/471 (53%), Gaps = 11/471 (2%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-------YWGGVCLNVGCIPSKALLRN 55 +DVVV+GAGPGGYVAAIRAAQLGL TA +E GG CLNVGCIPSKALL + Sbjct: 7 KFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDS 66 Query: 56 AELVHIFTKDAKAFGISGE-VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGT 114 + H + K GI + VT D R + + G+ L K N +T G+G Sbjct: 67 SYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGK 126 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV-TYEEQILSRELPKS 173 + V DG T+ + +N IIA+GS +P L+ +++ + + +PK Sbjct: 127 LLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKK 186 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + + GAG IG+E G V G +VT++E L + LP D ++KE K K G+ I Sbjct: 187 LGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGA 246 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 +V + QVTVT T Q+ +K++ A+G P +GV L +R I V Sbjct: 247 RVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYV 306 Query: 294 DDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 DD+ +T+V ++AIGDV LAH A +GV+ AE IAG + ++ ++P + P Sbjct: 307 DDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQ--MNYDLIPSVIYTHP 364 Query: 354 NVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVG 413 +A G TEQ + EG +V V FPF A+ +A D +G VK++ADAK +LG H++G Sbjct: 365 EIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIG 424 Query: 414 HDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 AEL+ + + + +A +L V +HPT+SEAL E + GH I+ Sbjct: 425 PSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHI 475 >5TR3-A nrPDB Length = 481 Score = 491 bits (1265), Expect = e-139, Method: Composition-based stats. Identities = 175/471 (37%), Positives = 249/471 (52%), Gaps = 11/471 (2%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY-------WGGVCLNVGCIPSKALLRN 55 +DVVV+GAGPGGYVAAI+AAQLGL TA +E GG CLNVGCIPSKALL + Sbjct: 7 KFDVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLALGGTCLNVGCIPSKALLDS 66 Query: 56 AELVHIFTKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGT 114 + + GIS GEV D R + + GV L K N +T I G+G Sbjct: 67 SWKYKEAKESFNVHGISTGEVKMDVAAMVGRKAGIVKNLTGGVATLFKANGVTSIQGHGK 126 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV-TYEEQILSRELPKS 173 + V DG TE + +N I+A+GS +P + NV+ + + +PK Sbjct: 127 LLAGKKVEVTKADGTTEVIEAENVILASGSRPIDIPPAPVDQNVIVDSTGALEFQAVPKR 186 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + + GAG IG+E G V G +VT++E L L D VSKE +K K G+ I Sbjct: 187 LGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTKQGLDIKLGA 246 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 +V G++V VT T Q++ +K++ A+G P +GV + +R I V Sbjct: 247 RVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRPVTTDLLASDSGVTIDERGYIFV 306 Query: 294 DDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 DDY T+V +YAIGDV + LAH A +G++ E I G + ++ ++P + P Sbjct: 307 DDYCATSVPGVYAIGDVVRGMMLAHKASEEGIMVVERIKGHKAQ--MNYDLIPSVIYTHP 364 Query: 354 NVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVG 413 +A G TEQ + EG +V V FPF A+ +A D GFVK++ADAK +LG H++G Sbjct: 365 EIAWVGKTEQALKAEGVEVNVGTFPFAASGRAMAANDTGGFVKVIADAKTDRVLGVHVIG 424 Query: 414 HDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 AEL+ + +A + +A +L V +HPT+SEAL E + G I+ Sbjct: 425 PSAAELVQQGAIAMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGGAIHV 475 >6N7F-A nrPDB Length = 453 Score = 489 bits (1258), Expect = e-138, Method: Composition-based stats. Identities = 128/450 (28%), Positives = 204/450 (45%), Gaps = 11/450 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 YD +V+G G G +A RAA G + E K GG C+N+GC+P K + A++ I Sbjct: 8 YDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVNLGCVPKKVMWYGAQVADILG 67 Query: 64 KDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 AK +G E FD+ + + A ++N + I+ Y F DA+T+ Sbjct: 68 TYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERGFEQNGVDRIYDYAVFKDAHTVE 127 Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAI 182 + + T + +IATG + P + ++ + E+PK + GAG I Sbjct: 128 I-----AGQLYTAPHILIATGGHP-VFPDIEGAQYGISSDGFFALDEVPKRTAVVGAGYI 181 Query: 183 GMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGG 242 +E VL G + R L + D + + + G + T +V + Sbjct: 182 AVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHTHAEVAKVVKNT 241 Query: 243 SQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVG 302 + KDG QE++ ++++ AIG PN+EG+ LDK GV L D+ I D Y T+V Sbjct: 242 DESLTLYLKDG--QEVEVDQLIWAIGRKPNLEGFSLDKTGVTLNDKGYIETDAYENTSVK 299 Query: 303 HIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTE 362 IYA+GDVNG L L VA A G +E + +T D++ + F P + S GL+E Sbjct: 300 GIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKLDYQNVATVIFSHPVIGSVGLSE 359 Query: 363 QQARNEG--YDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELL 420 + A + V + FT+ A +KLV +++G H +G+ V E++ Sbjct: 360 EAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMKLVTVGDTEKIVGLHGIGYGVDEMI 419 Query: 421 PELTLAQRWDLTASELARNVHTHPTMSEAL 450 +A + T ++ V HPT SE Sbjct: 420 QGFAVAIKMGATKADFDNTVAIHPTGSEEF 449 >3LAD-A nrPDB Length = 476 Score = 486 bits (1251), Expect = e-138, Method: Composition-based stats. Identities = 172/471 (36%), Positives = 249/471 (52%), Gaps = 11/471 (2%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-------KYWGGVCLNVGCIPSKALLRN 55 +DV+V+GAGPGGYVAAI++AQLGL TA++E GG CLNVGCIPSKALL + Sbjct: 3 KFDVIVIGAGPGGYVAAIKSAQLGLKTALIEKYKGKEGKTALGGTCLNVGCIPSKALLDS 62 Query: 56 AELVHIFTKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGT 114 + H + K GIS GEV D R ++ GV L+K N +T G+G Sbjct: 63 SYKFHEAHESFKLHGISTGEVAIDVPTMIARKDQIVRNLTGGVASLIKANGVTLFEGHGK 122 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV-TYEEQILSRELPKS 173 + V DG ++ + +N I+A+GS +P + +V+ + + +P Sbjct: 123 LLAGKKVEVTAADGSSQVLDTENVILASGSKPVEIPPAPVDQDVIVDSTGALDFQNVPGK 182 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + + GAG IG+E G V G +VT++E + + LP D V+KE +K K G+ IL Sbjct: 183 LGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLKILLGA 242 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 +V QVTV + +K++ A+G P +GV L +R I V Sbjct: 243 RVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYV 302 Query: 294 DDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 DDY T+V +YAIGDV LAH A +GVV AE IAG + ++ ++P + P Sbjct: 303 DDYCATSVPGVYAIGDVVRGAMLAHKASEEGVVVAERIAGHKAQ--MNYDLIPAVIYTHP 360 Query: 354 NVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVG 413 +A G TEQ + EG + V FPF A+ +A D +GFVK++ADAK +LG H++G Sbjct: 361 EIAGVGKTEQALKAEGVAINVGVFPFAASGRAMAANDTAGFVKVIADAKTDRVLGVHVIG 420 Query: 414 HDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 AEL+ + +A + +A +L V HP +SEAL E + GH I+ Sbjct: 421 PSAAELVQQGAIAMEFGTSAEDLGMMVFAHPALSEALHEAALAVSGHAIHV 471 >5J5Z-A nrPDB Length = 496 Score = 485 bits (1250), Expect = e-137, Method: Composition-based stats. Identities = 164/469 (34%), Positives = 244/469 (52%), Gaps = 11/469 (2%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIFT 63 DV V+G+GPGGYVAAI+AAQLG T +E + GG CLNVGCIPSKALL N+ H+ Sbjct: 30 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAH 89 Query: 64 -KDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTL 121 KD + GI EV + ++ + G+ L K+NK+ ++GYG N + Sbjct: 90 GKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQV 149 Query: 122 LVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV-TYEEQILSRELPKSIIIAGAG 180 DGGT+ + N +IATGS PG ++ + + + + +++P+ +++ GAG Sbjct: 150 TATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAG 209 Query: 181 AIGMEFGYVLKNYGVDVTIVEFLPRALP-NEDADVSKEIEKQFKKLGVTILTATKVESIA 239 IG+E G V + G DVT VEFL D ++SK ++ +K G TKV Sbjct: 210 VIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGAT 269 Query: 240 DGGSQ---VTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY 296 V++ G A+ + + +L IG P + GL++ G+ L R I V+ Sbjct: 270 KKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTR 329 Query: 297 MRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVA 356 +T + +IYAIGDV LAH AE +G++ E +AG D+ +P + P VA Sbjct: 330 FQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVH--IDYNCVPSVIYTHPEVA 387 Query: 357 SFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDV 416 G +E+Q + EG + V KFPF AN++A D G VK++ +LG H++G Sbjct: 388 WVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGA 447 Query: 417 AELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGL-VGHMINF 464 E++ E LA + + +AR H HPT+SEA +E G INF Sbjct: 448 GEMVNEAALALEYGASCEVIARVCHAHPTLSEAFREANLAASFGKSINF 496 >3URH-A nrPDB Length = 491 Score = 482 bits (1240), Expect = e-136, Method: Composition-based stats. Identities = 174/471 (36%), Positives = 252/471 (53%), Gaps = 9/471 (1%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-YWGGVCLNVGCIPSKALLRNAELV 59 M YD++V+G+GPGGYV AI+AAQLG+ A+VE + +GG CLNVGCIPSKALL +E+ Sbjct: 23 MMAYDLIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGGTCLNVGCIPSKALLHASEMF 82 Query: 60 HIFTKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADA 118 H +A G+ + + V GV FL KKNKI G G Sbjct: 83 HQAQHGLEALGVEVANPKLNLQKMMAHKDATVKSNVDGVSFLFKKNKIDGFQGTGKVLGQ 142 Query: 119 NTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSAN---VVTYEEQILSRELPKSII 175 + V G + + N +IATGS +PG ++ + +V+ + ++P S+I Sbjct: 143 GKVSVTNEKGEEQVLEAKNVVIATGSDVAGIPGVEVAFDEKTIVSSTGALALEKVPASMI 202 Query: 176 IAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKV 235 + G G IG+E G V G VT+VEFL L D +V+K++++ K G+ KV Sbjct: 203 VVGGGVIGLELGSVWARLGAKVTVVEFLDTILGGMDGEVAKQLQRMLTKQGIDFKLGAKV 262 Query: 236 ESIADGGS--QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 G +VT K G A L AE VL A G P+ +G GL KAGV L R + + Sbjct: 263 TGAVKSGDGAKVTFEPVKGGEATTLDAEVVLIATGRKPSTDGLGLAKAGVVLDSRGRVEI 322 Query: 294 DDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 D + +T++ +YAIGDV LAH AE +GV AE IAG ++ ++P + QP Sbjct: 323 DRHFQTSIAGVYAIGDVVRGPMLAHKAEDEGVAVAEIIAGQAGHV--NYDVIPGVVYTQP 380 Query: 354 NVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVG 413 VAS G TE++ + G + KFPFTAN +A + GFVK++AD + +LGGH++G Sbjct: 381 EVASVGKTEEELKAAGVAYKIGKFPFTANGRARAMLQTDGFVKILADKETDRVLGGHIIG 440 Query: 414 HDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 E++ E+ + + ++ +L R H HPTMSEA++E I+ Sbjct: 441 FGAGEMIHEIAVLMEFGGSSEDLGRTCHAHPTMSEAVKEAALSTFFKPIHM 491 >6BZ0-A nrPDB Length = 480 Score = 477 bits (1228), Expect = e-135, Method: Composition-based stats. Identities = 157/469 (33%), Positives = 240/469 (51%), Gaps = 10/469 (2%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK------YWGGVCLNVGCIPSKALLRNA 56 +D+VV+G GPGGY AAIRAAQLG A +E + GG CLNVGCIPSKALL ++ Sbjct: 7 QFDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALLDSS 66 Query: 57 ELVHIFTKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTF 115 GI+ GEV FD R K+ + G+ L+K N I + G G Sbjct: 67 HRYEDTVHHLADHGITTGEVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGIEWLKGTGKL 126 Query: 116 ADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV-TYEEQILSRELPKSI 174 + ++G T+ + I+A+GS +P + +++ + E+PK + Sbjct: 127 LAGKKVEFVPHEGETQILEPKYVILASGSVPVNIPVAPVDQDIIVDSTGALNFPEVPKRL 186 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATK 234 + GAG IG+E G V + G +V + E + LP D +SKE +K K G+ I K Sbjct: 187 GVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGLDIRIGAK 246 Query: 235 VESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVD 294 V G +VTV T+ G +E +K++ +G EG + +G+ LT+R + V+ Sbjct: 247 VSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLLAEDSGIKLTERGLVEVN 306 Query: 295 DYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPN 354 D+ T+V +YAIGD+ LAH A +GV+A E I G ++ + + P Sbjct: 307 DHCATSVEGVYAIGDLVRGPMLAHKAMEEGVMAVERIHGHAAQV--NYDTIISIIYTHPE 364 Query: 355 VASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGH 414 A GLTE+QA+ +G++V +F F N +A G+ +GFVK VADAK LLG H++G Sbjct: 365 AAWVGLTEEQAKEKGHEVKTGQFGFAVNGRALAAGEGAGFVKFVADAKTDRLLGMHVIGP 424 Query: 415 DVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMIN 463 ++++ + +A + + +L HPT SE + E + G I+ Sbjct: 425 AASDIVHQGMIALEFVSSVEDLQLMTFGHPTFSEVVHEAALAVDGRAIH 473 >5VDN-A nrPDB Length = 463 Score = 474 bits (1221), Expect = e-134, Method: Composition-based stats. Identities = 121/452 (26%), Positives = 194/452 (42%), Gaps = 11/452 (2%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61 HYD + +G G GG + RAA G A++E K GG C+NVGC+P K + A++ Sbjct: 16 KHYDYLAIGGGSGGIASINRAAMYGKKCALIEAKQLGGTCVNVGCVPKKVMWHAAQIAEA 75 Query: 62 FTKDAKAFGISGEVT-FDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 +G V FD+ + + NK+ I G+ F DA+T Sbjct: 76 IHLYGPDYGFDTTVNHFDWKKLIANRTAYIDRIHQSYERGLGNNKVDVIQGFARFVDAHT 135 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG 180 + V+ E++T D+ +IATG P + + + E+PK + + GAG Sbjct: 136 VEVN-----GETITADHILIATGGRPSH-PDIPGAEYGIDSDGFFELDEMPKRVAVVGAG 189 Query: 181 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD 240 I +E VL G + + L D + + + + G + T + +++ Sbjct: 190 YIAVEIAGVLNGLGTETHLFVRKHAPLRTFDPLIVETLLEVMNTEGPKLHTESVPKAVIK 249 Query: 241 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN 300 ++G E+ + ++ AIG P + L GV D+ I VD + TN Sbjct: 250 NADGSLTLQLENGT--EVTVDHLIWAIGREPATDNLNLSVTGVKTNDKGYIEVDKFQNTN 307 Query: 301 VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL 360 V IYA+GD G+++L VA A G +E + + D+ +P F P + + GL Sbjct: 308 VKGIYAVGDNTGVVELTPVAVAAGRRLSERLFNNKPDEHLDYSNIPTVVFSHPPIGTIGL 367 Query: 361 TEQQARNEGYD--VVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAE 418 TE QAR + D V V FTA A +KLV +++G H +G + E Sbjct: 368 TEPQAREKFGDDQVKVYTSSFTAMYSAVTQHRQPCRMKLVCVGAEEKIVGIHGIGFGMDE 427 Query: 419 LLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 +L +A + T + V HPT +E Sbjct: 428 ILQGFAVAMKMGATKKDFDNTVAIHPTAAEEF 459 >1GEU-A nrPDB Length = 450 Score = 474 bits (1220), Expect = e-134, Method: Composition-based stats. Identities = 124/452 (27%), Positives = 198/452 (43%), Gaps = 11/452 (2%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61 HYD + +G G GG + RAA G A++E K GG C+NVGC+P K + A++ Sbjct: 3 KHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVNVGCVPKKVMWHAAQIREA 62 Query: 62 FTKDAKAFGISGEVT-FDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 +G + F++ + ++ KN + I G+ F DA T Sbjct: 63 IHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENVLGKNNVDVIKGFARFVDAKT 122 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG 180 L V+ E++T D+ +IATG P + + LP+ + + GAG Sbjct: 123 LEVN-----GETITADHILIATGGRPSH-PDIPGVEYGIDSDGFFALPALPERVAVVGAG 176 Query: 181 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD 240 IG+E G V+ G + E LP+ D +S+ + + G + T +++ Sbjct: 177 YIGVELGGVINGLGAKTHLFEMFDAPLPSFDPMISETLVEVMNAEGPQLHTNAIPKAVVK 236 Query: 241 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN 300 +DG ++ + ++ AIG P + L+ AGV ++ I VD Y TN Sbjct: 237 NTDGSLTLELEDGRSET--VDCLIWAIGREPANDNINLEAAGVKTNEKGYIVVDKYQNTN 294 Query: 301 VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL 360 + IYA+GD G ++L VA A G +E + + D+ +P F P + + GL Sbjct: 295 IEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHLDYSNIPTVVFSHPPIGTVGL 354 Query: 361 TEQQARNEGYD--VVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAE 418 TE QAR + D V V K FTA A +KLV +++G H +G + E Sbjct: 355 TEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMKLVCVGSEEKIVGIHGIGFGMDE 414 Query: 419 LLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 +L +A + T + V HPT +E Sbjct: 415 MLQGFAVALKMGATKKDFDNTVAIHPTAAEEF 446 >1EBD-A nrPDB Length = 455 Score = 473 bits (1218), Expect = e-134, Method: Composition-based stats. Identities = 178/453 (39%), Positives = 255/453 (56%), Gaps = 5/453 (1%) Query: 7 VVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDA 66 +V+GAGPGGYVAAIRAAQLG IVE GGVCLNVGCIPSKAL+ + K + Sbjct: 7 LVVGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALISASHRYEQA-KHS 65 Query: 67 KAFGISGE-VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDL 125 + GI E VT D+ + V + GV L+K NK+ + G F DANT+ V + Sbjct: 66 EEMGIKAENVTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAYFVDANTVRV-V 124 Query: 126 NDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGME 185 N ++ TF NAIIATGS +P S ++ + E+PKS+++ G G IG+E Sbjct: 125 NGDSAQTYTFKNAIIATGSRPIELPNFKFSNRILDSTGALNLGEVPKSLVVIGGGYIGIE 184 Query: 186 FGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQV 245 G N+G VTI+E L + ++ I+K+ KK GV ++T + + V Sbjct: 185 LGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKKRLKKKGVEVVTNALAKGAEEREDGV 244 Query: 246 TVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIY 305 TVT +G + + A+ VL +G PN + GL++ G+ +T+R I VD RT+V +I+ Sbjct: 245 TVTYEANGETKTIDADYVLVTVGRRPNTDELGLEQIGIKMTNRGLIEVDQQCRTSVPNIF 304 Query: 306 AIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQA 365 AIGD+ LAH A +G VAAE IAG + D+ +P F P AS G EQQA Sbjct: 305 AIGDIVPGPALAHKASYEGKVAAEAIAGHPSAV--DYVAIPAVVFSDPECASVGYFEQQA 362 Query: 366 RNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTL 425 ++EG DV+ AKFPF AN +A + D GF+KLV + G ++G ++G + ++++ EL L Sbjct: 363 KDEGIDVIAAKFPFAANGRALALNDTDGFLKLVVRKEDGVIIGAQIIGPNASDMIAELGL 422 Query: 426 AQRWDLTASELARNVHTHPTMSEALQECFHGLV 458 A +TA ++A +H HPT+ E E + Sbjct: 423 AIEAGMTAEDIALTIHAHPTLGEIAMEAAEVAL 455 >1DXL-A nrPDB Length = 470 Score = 472 bits (1214), Expect = e-133, Method: Composition-based stats. Identities = 170/465 (36%), Positives = 249/465 (53%), Gaps = 7/465 (1%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIFT 63 DVV++G GPGGYVAAI+AAQLG T +E GG CLNVGCIPSKALL ++ + H Sbjct: 8 DVVIIGGGPGGYVAAIKAAQLGFKTTCIEKRGALGGTCLNVGCIPSKALLHSSHMYHEAK 67 Query: 64 KDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 G+ V D + K G+ L KKNK+T + GYG F + + Sbjct: 68 HSFANHGVKVSNVEIDLAAMMGQKDKAVSNLTRGIEGLFKKNKVTYVKGYGKFVSPSEIS 127 Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSAN-VVTYEEQILSRELPKSIIIAGAGA 181 VD +G V + IIATGS + +PG ++ +V+ + E+PK +++ GAG Sbjct: 128 VDTIEGENTVVKGKHIIIATGSDVKSLPGVTIDEKKIVSSTGALALSEIPKKLVVIGAGY 187 Query: 182 IGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADG 241 IG+E G V G +VT+VEF +P DA++ K+ ++ +K G+ TKV + Sbjct: 188 IGLEMGSVWGRIGSEVTVVEFASEIVPTMDAEIRKQFQRSLEKQGMKFKLKTKVVGVDTS 247 Query: 242 GSQVTVTVTKD--GVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRT 299 G V +TV G ++A+ VL + G P G LDK GV I V++ T Sbjct: 248 GDGVKLTVEPSAGGEQTIIEADVVLVSAGRTPFTSGLNLDKIGVETDKLGRILVNERFST 307 Query: 300 NVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFG 359 NV +YAIGDV LAH AE GV E +AG + D+ +P + P VAS G Sbjct: 308 NVSGVYAIGDVIPGPMLAHKAEEDGVACVEYLAGK--VGHVDYDKVPGVVYTNPEVASVG 365 Query: 360 LTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAEL 419 TE+Q + G + V KFPF AN++A + + G VK++A+ + ++LG H++ + EL Sbjct: 366 KTEEQVKETGVEYRVGKFPFMANSRAKAIDNAEGLVKIIAEKETDKILGVHIMAPNAGEL 425 Query: 420 LPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 + E +A ++D ++ ++AR H HPTMSEA++E I+ Sbjct: 426 IHEAAIALQYDASSEDIARVCHAHPTMSEAIKEAAMATYDKPIHI 470 >2YQU-A nrPDB Length = 455 Score = 464 bits (1195), Expect = e-131, Method: Composition-based stats. Identities = 172/463 (37%), Positives = 251/463 (54%), Gaps = 11/463 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIF 62 YD++V+GAGPGGYVAAIRAAQLG+ +VE K GG CL VGCIPSKALL E ++ Sbjct: 2 YDLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGGTCLRVGCIPSKALLETTERIYEA 61 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 K + G V D KV + GV FL KKN I G F +L Sbjct: 62 KKGLLGAKVKG-VELDLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTARFLSERKVL 120 Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVPGTSLS-ANVVTYEEQILSRELPKSIIIAGAGA 181 V+ E + +IATGS+ + P + VVT E + E+PK +I+ G G Sbjct: 121 VEE---TGEELEARYILIATGSAPLIPPWAQVDYERVVTSTEALSFPEVPKRLIVVGGGV 177 Query: 182 IGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADG 241 IG+E G V G +V ++E++ R LP D +VS+ E+ FKK G+TI T +V ++ Sbjct: 178 IGLELGVVWHRLGAEVIVLEYMDRILPTMDLEVSRAAERVFKKQGLTIRTGVRVTAVVPE 237 Query: 242 GSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNV 301 V + + L+A++VL A+G P EG L+ AG++ +R I VD+++RT V Sbjct: 238 AKGARVELE---GGEVLEADRVLVAVGRRPYTEGLSLENAGLSTDERGRIPVDEHLRTRV 294 Query: 302 GHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLT 361 HIYAIGDV LAH A +G+ A E + D++ +P + P +A+ G T Sbjct: 295 PHIYAIGDVVRGPMLAHKASEEGIAAVEHMV--RGFGHVDYQAIPSVVYTHPEIAAVGYT 352 Query: 362 EQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLP 421 E++ + +G V KFP++A+ +A +G+ GF+K++A AK +LG H +G V ++L Sbjct: 353 EEELKAQGIPYKVGKFPYSASGRARAMGETEGFIKVLAHAKTDRILGVHGIGARVGDVLA 412 Query: 422 ELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 E LA + +A +L R H HP++SE L+E I+ Sbjct: 413 EAALALFFKASAEDLGRAPHAHPSLSEILKEAALAAWERPIHL 455 >1V59-A nrPDB Length = 478 Score = 463 bits (1192), Expect = e-131, Method: Composition-based stats. Identities = 170/476 (35%), Positives = 248/476 (52%), Gaps = 16/476 (3%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVH 60 +DVV++G GP GYVAAI+AAQLG +TA VE GG CLNVGCIPSKALL N+ L H Sbjct: 4 KSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSHLFH 63 Query: 61 IFTKDAKAFGI--SGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADA 118 +A+ GI +G++ + + G+ L KKNK+T G G+F D Sbjct: 64 QMHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGSFEDE 123 Query: 119 NTLLVDLNDGGTESVTFDNA------IIATGSSTRLVPGTSLSA-NVVTYEEQILSRELP 171 + V DG +V D+ I+ATGS PG + +V+ + +E+P Sbjct: 124 TKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTGALSLKEIP 183 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 K + I G G IG+E G V G VT+VEF P+ + D +V+K +K KK G+ Sbjct: 184 KRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLKKQGLDFKL 243 Query: 232 ATKVESIADGGSQ----VTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 +TKV S + + V TK + L+AE +L A+G P + G G +K G+ + Sbjct: 244 STKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDK 303 Query: 288 RKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPR 347 R + +DD + HI +GDV LAH AE +G+ A E + ++ +P Sbjct: 304 RGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEMLKTGHGHV--NYNNIPS 361 Query: 348 ATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELL 407 + P VA G TE+Q + G D + KFPF AN++A D GFVK++ D+K +L Sbjct: 362 VMYSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQDTEGFVKILIDSKTERIL 421 Query: 408 GGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMIN 463 G H++G + E++ E LA + +A ++AR H HPT+SEA +E I+ Sbjct: 422 GAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANMAAYDKAIH 477 >2R9Z-A nrPDB Length = 463 Score = 463 bits (1192), Expect = e-131, Method: Composition-based stats. Identities = 129/452 (28%), Positives = 211/452 (46%), Gaps = 15/452 (3%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 H+D++ +G G GG A +AA G A++E K GG C+NVGC+P K + + L Sbjct: 4 HFDLIAIGGGSGGLAVAEKAAAFGKRVALIESKALGGTCVNVGCVPKKVMWYASHLAE-A 62 Query: 63 TKDAKAFGISGEV-TFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTL 121 +DA FG+ T D+ + + +++ IT + G+ F DA+T+ Sbjct: 63 VRDAPGFGVQASGGTLDWPRLVAGRDRYIGAINSFWDGYVERLGITRVDGHARFVDAHTI 122 Query: 122 LVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILSRELPKSIIIAGA 179 V+ + ++ D+ +IATG + +PG L +T + ++ PK + I GA Sbjct: 123 EVE-----GQRLSADHIVIATGGRPIVPRLPGAELG---ITSDGFFALQQQPKRVAIIGA 174 Query: 180 GAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIA 239 G IG+E +L+++G +VT+V R L D +S + + G+ V ++ Sbjct: 175 GYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLLSATLAENMHAQGIETHLEFAVAALE 234 Query: 240 DGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRT 299 T+ +DG E + V+ A+G APN GL+ AG+ + + D Y T Sbjct: 235 RDAQGTTLV-AQDGTRLE-GFDSVIWAVGRAPNTRDLGLEAAGIEVQSNGMVPTDAYQNT 292 Query: 300 NVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFG 359 NV +YA+GD+ G QL VA A G AE + ++ D+ +P F P ++ G Sbjct: 293 NVPGVYALGDITGRDQLTPVAIAAGRRLAERLFDGQSERKLDYDNIPTVVFAHPPLSKVG 352 Query: 360 LTEQQARNEGYDV-VVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAE 418 L+E +AR DV V + FT A P +KLV ++G H++G E Sbjct: 353 LSEPEARERLGDVLTVYETSFTPMRYALNEHGPKTAMKLVCAGPEQRVVGVHVIGDGADE 412 Query: 419 LLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 +L +A + T ++ V HP +E L Sbjct: 413 MLQGFAVAVKMGATKADFDNTVAIHPGSAEEL 444 >2QAE-A nrPDB Length = 468 Score = 461 bits (1187), Expect = e-130, Method: Composition-based stats. Identities = 168/454 (37%), Positives = 240/454 (52%), Gaps = 9/454 (1%) Query: 18 AAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGE-- 74 A+I+AAQLG+ TA VE GG CLNVGCIPSKALL L H + +G+ G Sbjct: 17 ASIKAAQLGMKTACVEKRGALGGTCLNVGCIPSKALLHATHLYHDAHANFARYGLMGGEG 76 Query: 75 VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVT 134 VT D + + +G GV +L KKNK+T G G+F A+++ V+ DG E + Sbjct: 77 VTMDSAKMQQQKERAVKGLTGGVEYLFKKNKVTYYKGEGSFETAHSIRVNGLDGKQEMLE 136 Query: 135 FDNAIIATGSSTRLVPGTSLSANVV-TYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNY 193 IIATGS +P VV + + +PK++++ G G IG+E G V Sbjct: 137 TKKTIIATGSEPTELPFLPFDEKVVLSSTGALALPRVPKTMVVIGGGVIGLELGSVWARL 196 Query: 194 GVDVTIVEFLPRALPNEDADVSKEIEKQF-KKLGVTILTATKVESIADGGSQVTVTVT-K 251 G +VT+VEF PR P D DV+ + K + +T+TKV + G V++ V K Sbjct: 197 GAEVTVVEFAPRCAPTLDEDVTNALVGALAKNEKMKFMTSTKVVGGTNNGDSVSLEVEGK 256 Query: 252 DGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVN 311 +G + + E +L ++G P G GLDK VA +R + + D+ T++ +YAIGDV Sbjct: 257 NGKRETVTCEALLVSVGRRPFTGGLGLDKINVAKNERGFVKIGDHFETSIPDVYAIGDVV 316 Query: 312 G-LLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGY 370 LAH AE +GV AE +AG ++ ++P + P VAS G +E + + EG Sbjct: 317 DKGPMLAHKAEDEGVACAEILAGKPGHV--NYGVIPAVIYTMPEVASVGKSEDELKKEGV 374 Query: 371 DVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWD 430 V KFPF AN++A V GFVK++ D +LG H+V EL+ E LA + Sbjct: 375 AYKVGKFPFNANSRAKAVSTEDGFVKVLVDKATDRILGVHIVCTTAGELIGEACLAMEYG 434 Query: 431 LTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 ++ ++ R H HPTMSEAL+E L INF Sbjct: 435 ASSEDVGRTCHAHPTMSEALKEACMALFAKTINF 468 >6AON-A nrPDB Length = 478 Score = 461 bits (1186), Expect = e-130, Method: Composition-based stats. Identities = 172/475 (36%), Positives = 249/475 (52%), Gaps = 14/475 (2%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVE-------PKYWGGVCLNVGCIPSKALLR 54 +DVVV+GAGPGGY+AAIRAAQLG+S A ++ GG C NVGCIPSKALL+ Sbjct: 6 KQFDVVVIGAGPGGYIAAIRAAQLGMSVACIDAWQNGQGGPAPGGTCTNVGCIPSKALLQ 65 Query: 55 NAELVHIFTKDAKAFGISGE-VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYG 113 ++E GI + V+ R V + G+ +L KKNK+T HG G Sbjct: 66 SSEHYEQANHHFAEHGIEVKGVSLKLDTLIGRKNTVVKQNNDGILYLFKKNKVTYFHGKG 125 Query: 114 TFADANTL--LVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEE-QILSREL 170 FA + + + + I+ATGSS R +PG + + + + Sbjct: 126 AFAGQVDGGWSIKVTGTTDADLVAKHVIVATGSSARELPGLPFDEKNILSNDGALNIGAV 185 Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL 230 PK + + GAG IG+E G V + G +VTI+E +P L D V+KE K F K G+ I Sbjct: 186 PKKLGVIGAGVIGLEMGSVWRRLGAEVTILEAMPEFLAAADQQVAKEALKSFAKQGLDIQ 245 Query: 231 TATKVESIADGGSQVTV-TVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRK 289 T K+ I +TV V G Q+L +K++ +IG P G + G+ L +R Sbjct: 246 TGVKIGEIKAAAKSITVPYVDAKGAEQKLVVDKLIVSIGRVPYTGGLNAEAVGLKLDERG 305 Query: 290 AIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRAT 349 + VD+ +TN+ +++A+GDV LAH AE +GV AE IAG + +P Sbjct: 306 FVAVDEDCKTNLPNVWAVGDVVRGPMLAHKAEEEGVAVAERIAGQHGHV--NFATVPWVI 363 Query: 350 FCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGG 409 + P +A G TEQQ + EG + FPF AN +A +GD +GF K++ADAK E+LG Sbjct: 364 YTSPEIAWVGKTEQQLKAEGREYKAGSFPFMANGRARALGDTTGFAKVIADAKTDEVLGV 423 Query: 410 HLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 H++G +EL+ E + A ++AR H HPT+SEA++E + +NF Sbjct: 424 HIIGPMASELISEAVTIMEFRGAAEDIARICHAHPTLSEAVKEAALAVDKRTLNF 478 >5U1O-A nrPDB Length = 458 Score = 460 bits (1184), Expect = e-130, Method: Composition-based stats. Identities = 117/453 (25%), Positives = 198/453 (43%), Gaps = 12/453 (2%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61 TH+D + +G G GG +A RAA G A++E + GG C+NVGC+P K + A++ Sbjct: 10 THFDYICIGGGSGGIASANRAAMYGAKVALIEAQDLGGTCVNVGCVPKKVMWHGAQIAEA 69 Query: 62 FTKDAKAFGISGEVT-FDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 A+ +G +V FD+ + + ++ NK+ I G+ F D T Sbjct: 70 MNLYAEDYGFDVDVKGFDWSKLVESRQAYIGRIHQSYDRVLGNNKVNVIKGFAKFVDEKT 129 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG 180 + V+ E T D+ +IA G +P + + E PK + + GAG Sbjct: 130 VEVN-----GEHYTADHILIAVGGRPT-IPNIPGAEYGIDSNGFFDLAEQPKRVAVVGAG 183 Query: 181 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD 240 I +E VL G + + L + D + + + + G T+ T + + + Sbjct: 184 YIAVEIAGVLHALGTETHLFVRKESPLRSFDPMIIDTLVEVMEAEGPTLHTHSVPKEVVK 243 Query: 241 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN 300 ++G +Q ++++ AIG P + L GVA ++ I VD+Y TN Sbjct: 244 EADGSLTLHLENGESQ--NVDQLIWAIGRHPATDAINLASTGVATNEKGYIKVDEYQETN 301 Query: 301 VGHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFG 359 V IY +GD+ G ++L VA G +E + + D+ ++P F P + + G Sbjct: 302 VKGIYCVGDIMEGGIELTPVAVKAGRQLSERLFNNKPNAKMDYDLVPTVVFSHPPIGTIG 361 Query: 360 LTEQQARNEGY--DVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVA 417 LT Q+A + ++ V FTA A +KLV + ++G H +G V Sbjct: 362 LTTQEAEEKYGKDNIKVYTSGFTAMYTAVTKHRQPCKMKLVCAGEEETVVGLHGIGFTVD 421 Query: 418 ELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 E++ +A + T ++ V HPT SE Sbjct: 422 EMIQGFGVAMKMGATKADFDSVVAIHPTGSEEF 454 >2EQ6-A nrPDB Length = 464 Score = 459 bits (1181), Expect = e-129, Method: Composition-based stats. Identities = 172/467 (36%), Positives = 246/467 (52%), Gaps = 12/467 (2%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH 60 M YD++V+G GPGGY AAIRAAQLGL VE GGVCLNVGCIP+KALL AE +H Sbjct: 4 MKTYDLIVIGTGPGGYHAAIRAAQLGLKVLAVEAGEVGGVCLNVGCIPTKALLHAAETLH 63 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 K A+ FG+ + D +V + GV L+K N + + G+ Sbjct: 64 HL-KVAEGFGLKAKPELDLKKLGGWRDQVVKKLTGGVGTLLKGNGVELLRGFARLVGPKE 122 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRE-LPKSIIIAGA 179 + V G E + I+ATGS + G +V + E LPK +++ G Sbjct: 123 VEV-----GGERYGAKSLILATGSEPLELKGFPFGEDVWDSTRALKVEEGLPKRLLVIGG 177 Query: 180 GAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIA 239 GA+G+E G V + G +VT++E++P LP D + + + + +K G+ + T TK Sbjct: 178 GAVGLELGQVYRRLGAEVTLIEYMPEILPQGDPETAALLRRALEKEGIRVRTKTKAVGYE 237 Query: 240 D--GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYM 297 G V + + G +E+ +KVL A+G P EG GL+KAGV + +R I V+ M Sbjct: 238 KKKDGLHVRLEPAEGGEGEEVVVDKVLVAVGRKPRTEGLGLEKAGVKVDERGFIRVNARM 297 Query: 298 RTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVAS 357 T+V +YAIGD LAH A +G++AAE AG ++ D++ +P + P A Sbjct: 298 ETSVPGVYAIGDAARPPLLAHKAMREGLIAAENAAGKDSAF--DYQ-VPSVVYTSPEWAG 354 Query: 358 FGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVA 417 GLTE++A+ GY V V KFP A+ +A +G G VK+V D + LLG +VG Sbjct: 355 VGLTEEEAKRAGYKVKVGKFPLAASGRALTLGGAEGMVKVVGDEETDLLLGVFIVGPQAG 414 Query: 418 ELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 EL+ E LA T ++LA VH HPT+SE+L E I+ Sbjct: 415 ELIAEAALALEMGATLTDLALTVHPHPTLSESLMEAAEAFHKQAIHI 461 >6B4O-A nrPDB Length = 452 Score = 458 bits (1180), Expect = e-129, Method: Composition-based stats. Identities = 122/453 (26%), Positives = 203/453 (44%), Gaps = 11/453 (2%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH 60 M YD +V+G G GG +A RA G + ++E GG C+NVGC+P K + + + ++ Sbjct: 4 MKTYDYIVIGGGSGGIASANRAGMHGANVLLIEGNEIGGTCVNVGCVPKKVMWQASSMME 63 Query: 61 IFTKDAKAFGISGEV-TFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADAN 119 + +D +G E+ F + + K + + + N I IHGY TF Sbjct: 64 MMERDTAGYGFDVEIKNFSFKQLVENREKYIDFLHGAYNRGLDSNNIERIHGYATFTGEQ 123 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGA 179 T+ V+ T + +IATG + + G + E+PK ++ GA Sbjct: 124 TIEVN-----GTEYTAPHILIATGGRPKKL-GIPGEEYALDSNGFFALEEMPKRVVFVGA 177 Query: 180 GAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIA 239 G I E L G + R L + D +S+++ ++++++G+ I I Sbjct: 178 GYIAAELAGTLHGLGAETHWAFRHERPLRSFDDMLSEKVVERYQEMGMQIHPNATPAKIE 237 Query: 240 DGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRT 299 V ++G + + + V+ G PN + GL+ VAL ++ + VD + T Sbjct: 238 KTAQNEYVITFENG--ESITTDAVIFGTGRQPNTDQLGLENTKVALDEKGYVKVDKFQNT 295 Query: 300 NVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFG 359 IYA+GDV G + L VA A G +E + +T D+ ++P F P VA+ G Sbjct: 296 TQNGIYAVGDVIGKIDLTPVAIAAGRRLSERLFNGQTDLYLDYNLVPTVVFTHPPVATIG 355 Query: 360 LTEQQARNEGYD--VVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVA 417 LTE+ A E + V + + FT A G +KL+ K +++G H +G V Sbjct: 356 LTEKAALEEYGEDQVKIYRSSFTPMYFALGEYRQKCDMKLICVGKEEKIVGLHGIGIGVD 415 Query: 418 ELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 E+L +A + T ++ V HPT SE Sbjct: 416 EMLQGFAVAIKMGATKADFDNTVAIHPTGSEEF 448 >6DU7-A nrPDB Length = 448 Score = 454 bits (1168), Expect = e-128, Method: Composition-based stats. Identities = 122/436 (27%), Positives = 203/436 (46%), Gaps = 16/436 (3%) Query: 20 IRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISG-EVTFD 78 RA + G A++E K GG C+NVGC+P K + A++ F + + +G ++ FD Sbjct: 20 NRAGEHGAQAAVIEEKKLGGTCVNVGCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFD 79 Query: 79 YGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNA 138 + + + K+N + I G+ F D++T+ V+ E + + Sbjct: 80 FATLRRNRESYIDRARSSYDGSFKRNGVDLIEGHAEFVDSHTVSVN-----GELIRAKHI 134 Query: 139 IIATGSSTRL--VPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVD 196 +IATG+ + +PG L + ++ ELP+S+ I GAG I +E VL +GV Sbjct: 135 VIATGAHPSIPNIPGAELGG---SSDDVFAWEELPESVAILGAGYIAVELAGVLHTFGVK 191 Query: 197 VTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQ 256 + R L D+ + + + K+ ++ + + T + +T+ +DG + Sbjct: 192 TDLFVRRDRPLRGFDSYIVEGLVKEMERTNLPLHTHKVPVKLEKTTDGITIHF-EDGTSH 250 Query: 257 ELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQL 316 A +V+ A G PNV+G L+KAGV L +R I VD+Y T V IYA+GDV G +L Sbjct: 251 T--ASQVIWATGRRPNVKGLQLEKAGVTLNERGFIQVDEYQNTVVEGIYALGDVTGEKEL 308 Query: 317 AHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGY--DVVV 374 VA G +E + +T D+ +P F P + + GLTE+QA E + V Sbjct: 309 TPVAIKAGRTLSERLFNGKTTAKMDYSTIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKV 368 Query: 375 AKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTAS 434 K F + A KL+ +++G H +G+ V E++ +A + T + Sbjct: 369 YKSSFASMYSACTRNRQESRFKLITAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKA 428 Query: 435 ELARNVHTHPTMSEAL 450 + V HPT SE Sbjct: 429 DFDATVAIHPTSSEEF 444 >5V36-A nrPDB Length = 453 Score = 453 bits (1165), Expect = e-128, Method: Composition-based stats. Identities = 122/452 (26%), Positives = 202/452 (44%), Gaps = 11/452 (2%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61 YD +V+G G GG +A RAA G + E K GG C+NVGC+P K + A++ Sbjct: 6 KQYDYIVIGGGSGGIASANRAAMHGAKVILFEGKQVGGTCVNVGCVPKKVMWYGAQVAET 65 Query: 62 FTKDAKAFGISGEVT-FDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 A +G F + + + + N + ++GY TF DA+T Sbjct: 66 INNYAADYGFDVTTQAFHFDVLKQNRQAYIDRIHDSYERGFDSNGVERVYGYATFVDAHT 125 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG 180 + V E T + +IATG L+P S +T + +PK + GAG Sbjct: 126 VEV-----AGEHYTAPHILIATGGHA-LLPDIPGSEYGITSDGFFELDAIPKRTAVVGAG 179 Query: 181 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD 240 I +E +L G + + R L D ++ + + KK G + T + + + Sbjct: 180 YIAVEISGILHALGSETHLFVRRDRPLRKFDKEIVGTLVDEMKKDGPHLHTFSVPKEVIK 239 Query: 241 GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN 300 + ++G +E + ++ AIG A N +G+ L+ GV L R I D + TN Sbjct: 240 NTDNSLTLILENG--EEYTVDTLIWAIGRAANTKGFNLEVTGVTLDSRGFIATDAFENTN 297 Query: 301 VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL 360 V +YA+GDVNG L+L VA G +E + + D++ + F P + S GL Sbjct: 298 VEGLYALGDVNGKLELTPVAVKAGRQLSERLFNHKPQAKMDYKDVATVIFSHPVIGSIGL 357 Query: 361 TEQQARNEGYD--VVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAE 418 +E+ A ++ + V V + FT+ A + +KLV + +++G H +G+ V E Sbjct: 358 SEEAALDQYGEENVTVYRSTFTSMYTAVTSHRQACKMKLVTVGEDEKIVGLHGIGYGVDE 417 Query: 419 LLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 ++ +A + T ++ V HPT SE Sbjct: 418 MIQGFAVAIKMGATKADFDNTVAIHPTGSEEF 449 >2HQM-A nrPDB Length = 479 Score = 450 bits (1158), Expect = e-127, Method: Composition-based stats. Identities = 119/460 (25%), Positives = 198/460 (43%), Gaps = 13/460 (2%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61 HYD +V+G G GG +A RAA G T +VE K GG C+NVGC+P K + ++L Sbjct: 10 KHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA-T 68 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFL-------MKKNKITEIHGYGT 114 A +G+ + D + + R A VH L ++K K+ + G+ Sbjct: 69 RVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWAR 128 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSI 174 F + V D TE + ++ ++ATG + E PK + Sbjct: 129 FNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKV 188 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATK 234 ++ GAG IG+E V G + +V L D + I + K G+ + +K Sbjct: 189 VVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSK 248 Query: 235 VESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVD 294 + + + + + ++++ IG ++ G G + G+ L I D Sbjct: 249 IVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIAD 307 Query: 295 DYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLT--LGDHRMLPRATFCQ 352 +Y TNV +IY++GDV G ++L VA A G + + G E D+ +P F Sbjct: 308 EYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSH 367 Query: 353 PNVASFGLTEQQARNEG--YDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGH 410 P S G++E++A + ++ V FTA A K+V + +++G H Sbjct: 368 PEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLH 427 Query: 411 LVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 +VG AE+L +A + T ++ V HPT +E L Sbjct: 428 IVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 467 >2AAQ-A nrPDB Length = 479 Score = 448 bits (1152), Expect = e-126, Method: Composition-based stats. Identities = 126/461 (27%), Positives = 205/461 (44%), Gaps = 21/461 (4%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 YD +V+G G GG +A RAA+LG A+VE GG C+NVGC+P K + A Sbjct: 22 YDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMH 81 Query: 64 KDAKAFGISG-EVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 A +G E F++ + ++ A + K+ I I G+ F Sbjct: 82 DHA-DYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPT 140 Query: 123 VDLNDGGTESVTFDNAIIATGSSTR-----LVPGTSLSANVVTYEEQILSRELPKSIIIA 177 +++ + T + +IATG +PG SL +T + ELP +I Sbjct: 141 IEV---SGKKYTAPHILIATGGMPSTPHESQIPGASLG---ITSDGFFQLEELPGRSVIV 194 Query: 178 GAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVES 237 GAG I +E +L G +++ + L + D+ +S ++ + GV +L ++V+ Sbjct: 195 GAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKE 254 Query: 238 IAD--GGSQVTVTVTKDGVAQEL----KAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAI 291 + G +V++ G + + +L AIG PN + L+K G+ D+ I Sbjct: 255 VKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHI 314 Query: 292 GVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFC 351 VD++ TNV IYA+GDV G L VA A G A + + + D+ +P F Sbjct: 315 IVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFS 374 Query: 352 QPNVASFGLTEQQARNEG--YDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGG 409 P + + GLTE +A ++ +V FT A +K+V K +++G Sbjct: 375 HPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGI 434 Query: 410 HLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 H+ G E+L +A + T ++ V HPT SE L Sbjct: 435 HMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 475 >1ZDL-A nrPDB Length = 517 Score = 445 bits (1144), Expect = e-125, Method: Composition-based stats. Identities = 118/469 (25%), Positives = 198/469 (42%), Gaps = 26/469 (5%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAI---VEPK------YWGGVCLNVGCIPSKALLR 54 +D++V+G G GG A AAQLG A+ VEP GG C+NVGCIP K + Sbjct: 33 FDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLM-H 91 Query: 55 NAELVHIFTKDAKAFGISG--EVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGY 112 A L+ +DA +G V ++ + + + G ++ K+ + Sbjct: 92 QAALLGGMIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIK 151 Query: 113 GTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLV-PGTSLSANVVTYEEQILSRELP 171 +F D +T+ G ++ ++ +IATG R +T ++ +E P Sbjct: 152 ASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITSDDIFWLKESP 211 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 ++ GA + +E L G+D T++ L D +S + + + G L Sbjct: 212 GKTLVVGASYVALECAGFLTGIGLDTTVM-MRSIPLRGFDQQMSSLVTEHMESHGTQFLK 270 Query: 232 A---TKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDR 288 + ++ + QVT G + VL AIG P L+KAG++ + Sbjct: 271 GCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGISTNPK 330 Query: 289 KA-IGVDDYMRTNVGHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLP 346 I VD T+V HIYAIGDV G +L A G + A+ + G + TL D+ +P Sbjct: 331 NQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSS-TLMDYSNVP 389 Query: 347 RATFCQPNVASFGLTEQQAR----NEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAK 402 F GL+E++A E +V A + A ++K+V + Sbjct: 390 TTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQ-CYIKMVCMRE 448 Query: 403 HGE-LLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 + +LG H +G + E+ L + + +++ + V HPT SE + Sbjct: 449 PPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEV 497 >6CMZ-A nrPDB Length = 466 Score = 443 bits (1139), Expect = e-124, Method: Composition-based stats. Identities = 159/466 (34%), Positives = 240/466 (51%), Gaps = 11/466 (2%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 H ++V+G GPGGYVAAIRA QLG+ T +VE GG CLN+GCIPSKAL+ A+ Sbjct: 8 HTTLLVIGGGPGGYVAAIRAGQLGIPTVLVERDRLGGTCLNIGCIPSKALIHVADAFEQA 67 Query: 63 TKDAK--AFGISGEVT-FDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADAN 119 A A GI D + + + GV L+KK+ + +HG D Sbjct: 68 CGHAGEGALGIRVRAPEIDIAKSVAWKDGIVDRLTRGVGALLKKSGVRVLHGEARVIDGK 127 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGA 179 T+ V ++ G + ++ ++ATGS +P +VV+ + + LPK +++ GA Sbjct: 128 TVEV-VSAGHAVRIGCEHLLLATGSEPVELPSMPFGGHVVSSTDALSPATLPKRLVVVGA 186 Query: 180 GAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIA 239 G IG+E G V + GVDV++VE R LP DA++ + + +LGV + KV + Sbjct: 187 GYIGLELGIVYRKLGVDVSVVEAAERVLPAYDAELVRPVADSLARLGVRLWLGHKVLGLD 246 Query: 240 DGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRK-AIGVDDYMR 298 G+ DG Q L A++VL A+G P V+G+GL+ + L A+ +DD R Sbjct: 247 KHGA--VRVQAADGAEQTLPADRVLVAVGRRPRVDGFGLET--LMLDRNGRALRIDDTCR 302 Query: 299 TNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASF 358 T++ +++AIGDV G LAH A AQG + AE IAG + +P F P + + Sbjct: 303 TSMRNVWAIGDVAGEPMLAHRAMAQGEMVAELIAGRRRQFM--PAAIPAVCFTDPEIVTA 360 Query: 359 GLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAE 418 G + A G D + A FPF AN +A + GFV++VA + ++G VG V+E Sbjct: 361 GWSPDDAHAAGVDCLSASFPFAANGRAMTLQATDGFVRVVARRDNHLIVGWQAVGRGVSE 420 Query: 419 LLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 L + + ++ +H HPT+ EALQE +GH ++ Sbjct: 421 LAAAFSQSLEMGARLEDIGGTIHAHPTLGEALQEAALRALGHALHV 466 >4JDR-A nrPDB Length = 474 Score = 440 bits (1132), Expect = e-124, Method: Composition-based stats. Identities = 171/464 (36%), Positives = 244/464 (52%), Gaps = 10/464 (2%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIFTK 64 VVVLGAGP GY AA R A LGL T IVE GGVCLNVGCIPSKALL A+++ Sbjct: 9 VVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVAKVIEEAKA 68 Query: 65 DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVD 124 A+ + GE D KV G+ + K K+ ++G G F ANTL V+ Sbjct: 69 LAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGANTLEVE 128 Query: 125 LNDGGTESVTFDNAIIATGSSTRLVPGTS-LSANVVTYEEQILSRELPKSIIIAGAGAIG 183 +G T + FDNAIIA GS +P + + + +E+P+ +++ G G IG Sbjct: 129 GENGKT-VINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLVMGGGIIG 187 Query: 184 MEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGS 243 +E G V G + +VE + +P D D+ K K+ K ++ TKV ++ Sbjct: 188 LEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKF-NLMLETKVTAVEAKED 246 Query: 244 QVTVTVT-KDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVG 302 + VT+ K A+ + + VL AIG PN + KAGV + DR I VD +RTNV Sbjct: 247 GIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRVDKQLRTNVP 306 Query: 303 HIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTE 362 HI+AIGD+ G LAH +G VAAE IAG + D +++P + +P VA GLTE Sbjct: 307 HIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYF--DPKVIPSIAYTEPEVAWVGLTE 364 Query: 363 QQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPE 422 ++A+ +G A FP+ A+ +A G KL+ D + ++GG +VG + ELL E Sbjct: 365 KEAKEKGISYETATFPWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVGTNGGELLGE 424 Query: 423 LTLAQRWDLTASELARNVHTHPTMSEAL---QECFHGLVGHMIN 463 + LA A ++A +H HPT+ E++ E F G + + N Sbjct: 425 IGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPN 468 >2X8H-A nrPDB Length = 598 Score = 438 bits (1127), Expect = e-123, Method: Composition-based stats. Identities = 117/477 (24%), Positives = 198/477 (41%), Gaps = 34/477 (7%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAI---VEPK------YWGGVCLNVGCIPSKALLR 54 YD++V+G G GG A AA+ G TA+ VEP GG C+NVGCIP K + Sbjct: 108 YDLIVIGGGSGGLAAGKEAAKYGAKTAVLDYVEPTPIGTTWGLGGTCVNVGCIPKKLM-H 166 Query: 55 NAELVHIFTKDAKAFGIS---GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHG 111 A L+ +DA+ FG S +++ ++ + + G ++ N++T ++ Sbjct: 167 QAGLLSHALEDAEHFGWSLDRSKISHNWSTMVEGVQSHIGSLNWGYKVALRDNQVTYLNA 226 Query: 112 YGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELP 171 G + + + + ++T + I+ATG + +T ++ P Sbjct: 227 KGRLISPHEVQITDKNQKVSTITGNKIILATGERPKYPEIPGAVEYGITSDDLFSLPYFP 286 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTI-- 229 ++ GA + +E L + G DVT++ L D +++++ + GV Sbjct: 287 GKTLVIGASYVALECAGFLASLGGDVTVMVRS-ILLRGFDQQMAEKVGDYMENHGVKFAK 345 Query: 230 ---------LTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDK 280 L E+ G V T DG E + E V+ A+G P + + Sbjct: 346 LCVPDEIKQLKVVDTENNKPGLLLVKGHYT-DGKKFEEEFETVIFAVGREPQLSKVLCET 404 Query: 281 AGVALTDRKAIGVDDYMRTNVGHIYAIGDVN-GLLQLAHVAEAQGVVAAETIAGAETLTL 339 GV L + D +T V ++YAIGD+N G QL VA G A + T L Sbjct: 405 VGVKLDKNGRVVCTDDEQTTVSNVYAIGDINAGKPQLTPVAIQAGRYLARRLFAGAT-EL 463 Query: 340 GDHRMLPRATFCQPNVASFGLTEQQARNEG----YDVVVAKFPFTANAKAHGVGDPSGFV 395 D+ + F + GL+E+ A + +V + F AH D ++ Sbjct: 464 TDYSNVATTVFTPLEYGACGLSEEDAIEKYGDKDIEVYHSNFKPLEWTVAHR-EDNVCYM 522 Query: 396 KLVADA-KHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQ 451 KLV + +LG H++G + E+ +A + T ++ R + HPT SE Sbjct: 523 KLVCRKSDNMRVLGLHVLGPNAGEITQGYAVAIKMGATKADFDRTIGIHPTCSETFT 579 >4LA1-A nrPDB Length = 602 Score = 434 bits (1116), Expect = e-122, Method: Composition-based stats. Identities = 109/461 (23%), Positives = 184/461 (39%), Gaps = 34/461 (7%) Query: 20 IRAAQLGLSTAI---VEPK------YWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFG 70 AA+ G A+ VEP GG C+NVGCIP K + A L+ +DA+ FG Sbjct: 130 KEAAKYGAKIAVLDYVEPTPMGTTWGLGGTCVNVGCIPKKLM-HQAGLLSHSLEDAQHFG 188 Query: 71 I---SGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLND 127 E++ D+ + + G ++ N +T ++ G + + + + Sbjct: 189 WSLDKSEISHDWSTMVEGVQSHIGSLNWGYKVSLRDNAVTYLNARGMLLSPHEVQITEKN 248 Query: 128 GGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFG 187 ++T + I+ATG + +T ++ P ++ GA + ++ Sbjct: 249 KKVSTITGNKIILATGERPKYPEIPGAIEYGITSDDLFSLPYFPGKTLVVGASYVALKCA 308 Query: 188 YVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTI-----------LTATKVE 236 L + G DVT++ L D +++++ + GV L E Sbjct: 309 GFLASLGGDVTVMVRS-ILLRGFDQQMAEKVGDYMENHGVKFAKLCVPDEITQLKPVDTE 367 Query: 237 SIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY 296 + G V T DG E + E V+ A+G P + + GV L + D Sbjct: 368 NNKPGLLLVKGHYT-DGKKFEEEFETVIFAVGREPQLSKLNCEAVGVKLDKNGRVVCSDD 426 Query: 297 MRTNVGHIYAIGDVN-GLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNV 355 +T V +IYAIGD+N G QL VA G A + T L D+ + F Sbjct: 427 EQTTVSNIYAIGDINAGKPQLTPVAIHAGRYLARRLFAGAT-ELTDYSNVATTVFTPLEY 485 Query: 356 ASFGLTEQQARNEG----YDVVVAKFPFTANAKAHGVGDPSGFVKLVAD-AKHGELLGGH 410 + GL+E+ A + +V + F AH D ++KLV + + +LG H Sbjct: 486 GACGLSEEDAIEKYGDNDIEVYHSHFKPLEWTVAHR-EDNVCYMKLVCRISDNMRVLGLH 544 Query: 411 LVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQ 451 ++G + E+ +A + T + R + HPT SE Sbjct: 545 VLGPNAGEITQGYAVAIKMGATKEDFDRTIGIHPTCSETFT 585 >1LVL-A nrPDB Length = 458 Score = 433 bits (1114), Expect = e-122, Method: Composition-based stats. Identities = 154/462 (33%), Positives = 245/462 (53%), Gaps = 14/462 (3%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKD 65 ++++G GPGGYVAAIRA QLG+ T +VE + GG CLN+GCIPSKAL+ AE H ++ Sbjct: 8 LLIIGGGPGGYVAAIRAGQLGIPTVLVEGQALGGTCLNIGCIPSKALIHVAEQFHQASRF 67 Query: 66 AKA--FGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 + GIS D G + + + GV L+KK+ + +HG+ D + Sbjct: 68 TEPSPLGISVASPRLDIGQSVAWKDGIVDRLTTGVAALLKKHGVKVVHGWAKVLDGKQVE 127 Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAI 182 VD + + ++ ++ATGSS+ +P L V++ E + + LP+ +++ G G I Sbjct: 128 VD-----GQRIQCEHLLLATGSSSVELPMLPLGGPVISSTEALAPKALPQHLVVVGGGYI 182 Query: 183 GMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGG 242 G+E G + G V++VE R LP D++++ + + KKLG+ + VE +G Sbjct: 183 GLELGIAYRKLGAQVSVVEARERILPTYDSELTAPVAESLKKLGIALHLGHSVEGYENG- 241 Query: 243 SQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVG 302 + G L+A++VL A+G P +G+ L+ + + AI +D+ +T++ Sbjct: 242 --CLLANDGKGGQLRLEADRVLVAVGRRPRTKGFNLECLDLKMN-GAAIAIDERCQTSMH 298 Query: 303 HIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTE 362 +++AIGDV G LAH A AQG + AE IAG + + F P V G T Sbjct: 299 NVWAIGDVAGEPMLAHRAMAQGEMVAEIIAGKARRF--EPAAIAAVCFTDPEVVVVGKTP 356 Query: 363 QQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPE 422 +QA +G D +VA+FPF AN +A + SGFV++VA + +LG VG V+EL Sbjct: 357 EQASQQGLDCIVAQFPFAANGRAMSLESKSGFVRVVARRDNHLILGWQAVGVAVSELSTA 416 Query: 423 LTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 + ++A +H HPT+ EA+QE +GH ++ Sbjct: 417 FAQSLEMGACLEDVAGTIHAHPTLGEAVQEAALRALGHALHI 458 >2YAU-A nrPDB Length = 511 Score = 433 bits (1113), Expect = e-121, Method: Composition-based stats. Identities = 125/469 (26%), Positives = 201/469 (42%), Gaps = 27/469 (5%) Query: 4 YDVVVLGAGPGGYVAAIRAA-QLGLSTAIVEPKY---------WGGVCLNVGCIPSKALL 53 YD+VVLGAG GG A AA A+V+ + GG C+NVGC+P K ++ Sbjct: 25 YDLVVLGAGSGGLEAGWNAAVTHKKKVAVVDVQATHGPPLFAALGGTCVNVGCVPKKLMV 84 Query: 54 RNAELVHIFTKDAKAFGISGE---VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIH 110 A+ + + + + FG + + ++ KV + + H Sbjct: 85 TGAQYMDLIRE-SGGFGWEMDRESLCPNWKTLIAAKNKVVNSINESYKSMFADTEGLSFH 143 Query: 111 -GYGTFADANTLLV----DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQI 165 G+G DA+T++V D + E++ + +IATGS + G +T E Sbjct: 144 MGFGALQDAHTVVVRKSEDPHSDVLETLDTEYILIATGSWPTRL-GVPGDEFCITSNEAF 202 Query: 166 LSRELPKSIIIAGAGAIGMEFGYVLKNY---GVDVTIVEFLPRALPNEDADVSKEIEKQF 222 + PK ++ G G I +EF + Y G V + L D +V K + KQ Sbjct: 203 YLEDAPKRMLCVGGGYIAVEFAGIFNGYKPCGGYVDLCYRGDLILRGFDTEVRKSLTKQL 262 Query: 223 KKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAG 282 G+ + T I DG + ++V+ AIG P + LDKAG Sbjct: 263 GANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEE--DYDQVMLAIGRVPRSQALQLDKAG 320 Query: 283 VALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDH 342 V A+ VD Y +T+V +IYAIGDV + L VA +G ET+ G + DH Sbjct: 321 VRTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGAAFVETVFGGKPRAT-DH 379 Query: 343 RMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTA-NAKAHGVGDPSGFVKLVADA 401 + A F P + + G+TE++A V V FT G ++++ + Sbjct: 380 TKVACAVFSIPPIGTCGMTEEEAAKNYETVAVYASSFTPLMHNISGSKHKEFMIRIITNE 439 Query: 402 KHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 +GE+LG H++G E++ + + + S+ + HPT +E L Sbjct: 440 SNGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTIGVHPTSAEEL 488 >2WOV-A nrPDB Length = 495 Score = 430 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 122/471 (25%), Positives = 197/471 (41%), Gaps = 27/471 (5%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQ-LGLSTAIVEPKY---------WGGVCLNVGCIPSKA 51 +D+VV+GAG GG A AA G A+V+ + GG C+NVGC+P K Sbjct: 6 KAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKL 65 Query: 52 LLRNAELVHIFTKDAKAFGISGE---VTFDYGIAYDRSRKVAEGRVAGVHFLM-KKNKIT 107 ++ A+ + + A FG + V ++ + + + Sbjct: 66 MVTGAQYMDHLRESA-GFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLD 124 Query: 108 EIHGYGTFADANTLLV----DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEE 163 G+G+ N ++V D E + D+ ++ATGS ++ P + ++ E Sbjct: 125 FFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQM-PAIPGIEHCISSNE 183 Query: 164 QILSRELPKSIIIAGAGAIGMEFGYVLKNY---GVDVTIVEFLPRALPNEDADVSKEIEK 220 E P+ ++ G G I +EF + Y G VT+ L D + +E+ K Sbjct: 184 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 243 Query: 221 QFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDK 280 Q G+ I+T ++ + G + L + V+ AIG P L Sbjct: 244 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESG--KTLDVDVVMMAIGRIPRTNDLQLGN 301 Query: 281 AGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLG 340 GV LT + + VD++ RTNV +IYAIGD+ L L VA +G +T+ G + Sbjct: 302 VGVKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKP-RKT 360 Query: 341 DHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTA-NAKAHGVGDPSGFVKLVA 399 DH + A F P + + GL E+ A E V V FT G K+V Sbjct: 361 DHTRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVT 420 Query: 400 DAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 + G +LG HL+G E++ + + R + S+ + HPT +E L Sbjct: 421 NHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEEL 471 >1FEC-A nrPDB Length = 490 Score = 427 bits (1098), Expect = e-120, Method: Composition-based stats. Identities = 125/469 (26%), Positives = 199/469 (42%), Gaps = 27/469 (5%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLS-TAIVEPKY---------WGGVCLNVGCIPSKALL 53 YD+VV+GAG GG A AA L A+++ + GG C+NVGC+P K ++ Sbjct: 4 YDLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPKKLMV 63 Query: 54 RNAELVHIFTKDAKAFGISGE---VTFDYGIAYDRSRKVAEGRVAGVHFLM-KKNKITEI 109 A + + A FG + V ++ K G + +T Sbjct: 64 TGANYMDTIRESA-GFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTEGLTFH 122 Query: 110 HGYGTFADANTLLV----DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQI 165 G+G D +T+LV D N E++ + ++ATGS + + G +T E Sbjct: 123 QGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHL-GIEGDDLCITSNEAF 181 Query: 166 LSRELPKSIIIAGAGAIGMEFGYVLKNY---GVDVTIVEFLPRALPNEDADVSKEIEKQF 222 E PK + G G I +EF + Y G V + L D+++ K++ +Q Sbjct: 182 YLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRKQLTEQL 241 Query: 223 KKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAG 282 + G+ + T + V + G E + V+ AIG P + L+KAG Sbjct: 242 RANGINVRTHENPAKVTKNADGTRHVVFESGA--EADYDVVMLAIGRVPRSQTLQLEKAG 299 Query: 283 VALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDH 342 V + AI VD Y +TNV +IYAIGDV + L VA +G +T+ + DH Sbjct: 300 VEVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFANKPRAT-DH 358 Query: 343 RMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTA-NAKAHGVGDPSGFVKLVADA 401 + A F P + G E+ A + V V + FT G V++V + Sbjct: 359 TKVACAVFSIPPMGVCGYVEEDAAKKYDQVAVYESSFTPLMHNISGSTYKKFMVRIVTNH 418 Query: 402 KHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 GE+LG H++G E++ + + + S+ + HPT +E L Sbjct: 419 ADGEVLGVHMLGDSSPEIIQSVAICLKMGAKISDFYNTIGVHPTSAEEL 467 >3O0H-A nrPDB Length = 484 Score = 426 bits (1096), Expect = e-119, Method: Composition-based stats. Identities = 125/448 (27%), Positives = 204/448 (45%), Gaps = 9/448 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 +D+ V+G+G GG AA A LG AI E GG C+ GC+P K ++ F+ Sbjct: 27 FDLFVIGSGSGGVRAARLAGALGKRVAIAEEYRIGGTCVIRGCVPKKLYFYASQYAQEFS 86 Query: 64 KDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 K FG + F++ K ++ + + F D +TL Sbjct: 87 KSI-GFGWKYADPIFNWEKLVAAKNKEISRLEGLYREGLQNSNVHIYESRAVFVDEHTLE 145 Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAI 182 + + E ++ + +IATG+ S +T E +LPKSI+I G G I Sbjct: 146 LSV---TGERISAEKILIATGAKIVSNSAIKGSDLCLTSNEIFDLEKLPKSIVIVGGGYI 202 Query: 183 GMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGG 242 G+EF + GV T++ L N D D+ + + G++I+ V + Sbjct: 203 GVEFANIFHGLGVKTTLLHRGDLILRNFDYDLRQLLNDAMVAKGISIIYEATVSQVQSTE 262 Query: 243 SQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVG 302 + V +T Q + A++V+ A G PN G GL++AGV + + A+ VD+ M TNV Sbjct: 263 NCYNVVLTN---GQTICADRVMLATGRVPNTTGLGLERAGVKVNEFGAVVVDEKMTTNVS 319 Query: 303 HIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTE 362 HI+A+GDV G +QL VA + + T T D+ ++ A F QP + + GL+E Sbjct: 320 HIWAVGDVTGHIQLTPVAIHDAMCFVKNAF-ENTSTTPDYDLITTAVFSQPEIGTVGLSE 378 Query: 363 QQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPE 422 + A + V + + F F+KLV D + ++G H++G + E+ Sbjct: 379 EDALHRYKRVEIYRTVFRPMRNVLSGSPEKMFMKLVVDGESRIVVGAHVLGENAGEIAQL 438 Query: 423 LTLAQRWDLTASELARNVHTHPTMSEAL 450 + ++ + LT + + HPTMSE L Sbjct: 439 IGISLKGKLTKDIFDKTMAVHPTMSEEL 466 >4KPR-E nrPDB Length = 499 Score = 426 bits (1095), Expect = e-119, Method: Composition-based stats. Identities = 106/456 (23%), Positives = 190/456 (41%), Gaps = 28/456 (6%) Query: 20 IRAAQLGLSTAIVE---------PKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFG 70 AA+ +++ GG C+NVGCIP K + A L+ KD++ +G Sbjct: 29 KEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLM-HQAALLGQALKDSRNYG 87 Query: 71 ISGE--VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDG 128 E V D+ + + G +++ K+ + YG F + ++ N G Sbjct: 88 WKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKVVYENAYGKFIGPHKIMATNNKG 147 Query: 129 GTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGY 188 + + + +IATG R + ++ ++ P ++ GA + +E Sbjct: 148 KEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAG 207 Query: 189 VLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL---TATKVESIADGGS-- 243 L G+DVT++ L D D++ +I + ++ G+ + TK+E I G Sbjct: 208 FLAGIGLDVTVMVRS-ILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGR 266 Query: 244 -QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDR-KAIGVDDYMRTNV 301 +VT T E + VL A+G GL+ GV + ++ I V D +TNV Sbjct: 267 LKVTAKSTNSEETIEDEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNV 326 Query: 302 GHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL 360 +IYAIGD+ G L+L VA G + A+ + G T+ D+ +P F GL Sbjct: 327 PYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSTVKC-DYDNVPTTVFTPLEYGCCGL 385 Query: 361 TEQQAR----NEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVAD-AKHGELLGGHLVGHD 415 +E++A E +V + F + + K++ + + ++G H++G + Sbjct: 386 SEEKAVEKFGEENIEVYHSFFWPLEWTVP-SRDNNKCYAKVICNLKDNERVVGFHVLGPN 444 Query: 416 VAELLPELTLAQRWDLTASELARNVHTHPTMSEALQ 451 E+ A + LT +L + HP +E Sbjct: 445 AGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFT 480 >5X1Y-B nrPDB Length = 554 Score = 424 bits (1090), Expect = e-119, Method: Composition-based stats. Identities = 133/462 (28%), Positives = 234/462 (50%), Gaps = 10/462 (2%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 +YD++++G+G + +AI+A + G ++E GG C+N+GC+PSK LLR E++H Sbjct: 84 NYDLLIIGSGAAAFSSAIKAIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEIIH-L 142 Query: 63 TKDAKAFGISGEV-TFDYGIAYDRSRKVA-EGRVAGVHFLMKKNKITEIHGYGTFADANT 120 +KD G+ D + K+ E R L+ + I G F DA+T Sbjct: 143 SKDNPFIGLQTSAGEVDLASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDAST 202 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSA-NVVTYEEQILSRELPKSIIIAGA 179 + V+ ++ +IATG+S L + L + +T + +++PK + + G+ Sbjct: 203 VEVNGAK-----LSAKRFLIATGASPSLPQISGLEKMDYLTSTTLLELKKIPKRLTVIGS 257 Query: 180 GAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIA 239 G IGME G + + G ++T+++ R L D ++S+ +EK + G+ ++ E + Sbjct: 258 GYIGMELGQLFHHLGSEITLMQRSERLLKEYDPEISESVEKALIEQGINLVKGATFERVE 317 Query: 240 DGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRT 299 G V VT +G + ++++++L A G PN + L AGV I ++D+ +T Sbjct: 318 QSGEIKRVYVTVNGSREVIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEILINDFGQT 377 Query: 300 NVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFG 359 + IYA GDV Q +VA +G + + G D ++P TF P VA+ G Sbjct: 378 SNEKIYAAGDVTLGPQFVYVAAYEGGIITDNAIGG-LNKKIDLSVVPAVTFTNPTVATVG 436 Query: 360 LTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAEL 419 LTE+QA+ +GYDV + P A +A + +G KLVADA+ ++LG H+V + ++ Sbjct: 437 LTEEQAKEKGYDVKTSVLPLDAVPRAIVNRETTGVFKLVADAETLKVLGVHIVSENAGDV 496 Query: 420 LPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHM 461 + +LA ++ LT +L + + TM+E L+ + Sbjct: 497 IYAASLAVKFGLTVEDLTETLAPYLTMAEGLKLAALTFDKDI 538 >2CFY-A nrPDB Length = 521 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 102/456 (22%), Positives = 189/456 (41%), Gaps = 28/456 (6%) Query: 20 IRAAQLGLSTAIVE---------PKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFG 70 AAQ G +++ GG C+NVGCIP K + A L+ +D++ +G Sbjct: 51 KEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLM-HQAALLGQALQDSRNYG 109 Query: 71 ISGE--VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDG 128 E V D+ + + G +++ K+ + YG F + + N G Sbjct: 110 WKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKG 169 Query: 129 GTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGY 188 + + + +IATG R + ++ ++ P ++ GA + +E Sbjct: 170 KEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAG 229 Query: 189 VLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL---TATKVESIADGGSQV 245 L G+DVT++ L D D++ +I + ++ G+ + KVE I G Sbjct: 230 FLAGIGLDVTVMVRS-ILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGR 288 Query: 246 TVTVTKDGVAQEL---KAEKVLQAIGFAPNVEGYGLDKAGVALTDR-KAIGVDDYMRTNV 301 V + ++E+ + V+ AIG GL+ GV + ++ I V D +TNV Sbjct: 289 LRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNV 348 Query: 302 GHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL 360 +IYAIGD+ ++L VA G + A+ + T+ D+ +P F + GL Sbjct: 349 PYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKC-DYENVPTTVFTPLEYGACGL 407 Query: 361 TEQQAR----NEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVAD-AKHGELLGGHLVGHD 415 +E++A E +V + F + + K++ + + ++G H++G + Sbjct: 408 SEEKAVEKFGEENIEVYHSYFWPLEWTIP-SRDNNKCYAKIICNTKDNERVVGFHVLGPN 466 Query: 416 VAELLPELTLAQRWDLTASELARNVHTHPTMSEALQ 451 E+ A + LT +L + HP +E Sbjct: 467 AGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFT 502 >4NEW-A nrPDB Length = 492 Score = 419 bits (1078), Expect = e-117, Method: Composition-based stats. Identities = 115/471 (24%), Positives = 197/471 (41%), Gaps = 28/471 (5%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQ-LGLSTAIVEPK---------YWGGVCLNVGCIPSKA 51 +D+VV+GAG GG AA AA A+++ + GG C+NVGC+P K Sbjct: 4 KIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKL 63 Query: 52 LLRNAELVHIFTKDAKAFGISGE---VTFDYGIAYDRSRKVAEGRVAGVHFLMKK-NKIT 107 ++ A+ + + A FG + + ++ + + + + Sbjct: 64 MVTGAQYMEHLRESA-GFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEGLE 122 Query: 108 EIHGYGTFADANTLLV----DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEE 163 G+G+ N + V D E + ++ ++A+GS + P + ++ E Sbjct: 123 FFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHM-PNIPGIEHCISSNE 181 Query: 164 QILSRELPKSIIIAGAGAIGMEFGYVLKNYGVD---VTIVEFLPRALPNEDADVSKEIEK 220 E P+ ++ G G I +EF + Y VT+ L D + +E+ K Sbjct: 182 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 241 Query: 221 QFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDK 280 Q G+ ILT + + G +++ + V+ AIG +P + L Sbjct: 242 QLTANGIQILTKENPAKVELNADGSKSVTFESG--KKMDFDLVMMAIGRSPRTKDLQLQN 299 Query: 281 AGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLG 340 AGV + + VD+Y RTNV +IYAIGDV + L VA + +T+ G T Sbjct: 300 AGVMI-KNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFG-TTPRKT 357 Query: 341 DHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTA-NAKAHGVGDPSGFVKLVA 399 DH + A F P + + GL E+ A V V FT K G + K++ Sbjct: 358 DHTRVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIIT 417 Query: 400 DAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 + G +LG HL+G + E++ + + + + S+ + HPT +E L Sbjct: 418 NHSDGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEEL 468 >5W1J-A nrPDB Length = 584 Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats. Identities = 118/474 (24%), Positives = 188/474 (39%), Gaps = 31/474 (6%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE-------PKYWG--GVCLNVGCIPSKALLR 54 YD+V++G G GG A +A+ G A+++ WG G C+NVGCIP K + Sbjct: 104 YDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGTCVNVGCIPKKLM-H 162 Query: 55 NAELVHIFTKDAKAFGISGEV-TFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYG 113 A L++ + +DAK+FG + D+ + + G M + ++ G Sbjct: 163 QAALLNHYMEDAKSFGWDVDKGPHDWVKMVEGIQDHIHALNFGYRSSMMNANVKYLNALG 222 Query: 114 TFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKS 173 D +T+ G +++T + I+ATG R P +T ++ P Sbjct: 223 EIVDPHTIKTTNKQGIVKNITTNTIIVATGERPRYPPIPGAKEYGITSDDLFTLDHNPGK 282 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + GA + +E L + G DVT++ L D ++ I K GV + Sbjct: 283 TLCVGASYVSLECAGFLSSIGCDVTVMVRS-IFLRGFDQQMAGLISDYIAKYGVKFVRPC 341 Query: 234 KVESI-------ADGGSQVTVTVT---KDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGV 283 S+ + G V +DG + VL A+G P GL V Sbjct: 342 VPTSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTNIGLQNVDV 401 Query: 284 ALTDRKAIGVDDYMRTNVGHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGAETLTLGDH 342 T + VDD RTNV +IYAIGDV N QL +A G A + A+ D+ Sbjct: 402 KTT-NGRVVVDDEERTNVPNIYAIGDVSNAGYQLTPLAIQAGKNLARRLYTADDCRT-DY 459 Query: 343 RMLPRATFCQPNVASFGLTEQQAR----NEGYDVVVAKFPFTANAKAHGVGDPSGFVKLV 398 +P F GL+E+ A + +V + F H D + + KL+ Sbjct: 460 TNVPTTVFTPLEYGCIGLSEENAISKFGEDNIEVFHSYFQPLEWTVPHRP-DNTCYAKLI 518 Query: 399 ADA-KHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQ 451 + ++G H+ G + E+ +A + R + HPT SE Sbjct: 519 INKQDDNRVVGFHVFGPNAGEVTQGYAVAMHLGARKEDFDRTIGIHPTCSETFT 572 >4B1B-A nrPDB Length = 542 Score = 410 bits (1053), Expect = e-115, Method: Composition-based stats. Identities = 105/484 (21%), Positives = 193/484 (39%), Gaps = 38/484 (7%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE-------PKYWG--GVCLNVGCIPSKALLR 54 YD VV+G GPGG +A AA G + + WG G C+NVGC+P K + Sbjct: 43 YDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMHY 102 Query: 55 NAELVHIFTKDAKAFGISGE-VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYG 113 + IF D+KA+G + + D+ + ++ +K+ I+G Sbjct: 103 AGHMGSIFKLDSKAYGWKFDNLKHDWKKLVTTVQSHIRSLNFSYMTGLRSSKVKYINGLA 162 Query: 114 TFADANTLLVDLNDG--GTESVTFDNAIIATGSSTRLVPGTSLSANV-VTYEEQILSREL 170 D NT+ L E+VT +IATG + + + +T ++ ++ Sbjct: 163 KLKDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELSITSDDIFSLKKD 222 Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL 230 P ++ GA + +E L + G DVT+ L D + +++ ++ GV Sbjct: 223 PGKTLVVGASYVALECSGFLNSLGYDVTV-AVRSIVLRGFDQQCAVKVKLYMEEQGVMFK 281 Query: 231 TATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD-RK 289 + + ++ V + + VL AIG +++G L+ + + Sbjct: 282 NGILPKKLTKMDDKILVEFSDKTSEL---YDTVLYAIGRKGDIDGLNLESLNMNVNKSNN 338 Query: 290 AIGVDDYMRTNVGHIYAIGDV-NGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRA 348 I D TN+ I+A+GDV + +LA VA G + A + ++ + D+ +P + Sbjct: 339 KIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRLF-KDSDEIMDYSYIPTS 397 Query: 349 TFCQPNVASFGLTEQQARNEG----YDVVVAKFPFTANAKAHGVGD-------------P 391 + + G +E++A +V + +F + H Sbjct: 398 IYTPIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAVHRQKHIRAQKDEYDLDVSS 457 Query: 392 SGFVKLVA-DAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 450 + KLV + ++G H VG + E+ + LA R + + + HPT +E+ Sbjct: 458 TCLAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALRLKVKKKDFDNCIGIHPTDAESF 517 Query: 451 QECF 454 F Sbjct: 518 MNLF 521 >2NVK-X nrPDB Length = 488 Score = 409 bits (1052), Expect = e-114, Method: Composition-based stats. Identities = 122/472 (25%), Positives = 193/472 (40%), Gaps = 27/472 (5%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE--------PKYWG--GVCLNVGCIPSKALL 53 YD++V+G G G A A G A ++ WG G C+NVGCIP K + Sbjct: 10 YDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLM- 68 Query: 54 RNAELVHIFTKDAKAFGISGE--VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHG 111 A L+ +A A+G + + + D+ + + ++ K+ I+G Sbjct: 69 HQASLLGEAVHEAAAYGWNVDDKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYING 128 Query: 112 YGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELP 171 G+F D++TLL L G ++T +IA G R +T ++ P Sbjct: 129 LGSFVDSHTLLAKLKSG-ERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREP 187 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 ++ GAG IG+E LK G + T++ L D +++ + ++ G+ L Sbjct: 188 GKTLVVGAGYIGLECAGFLKGLGYEPTVMVRS-IVLRGFDQQMAELVAASMEERGIPFLR 246 Query: 232 ATK---VESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDR 288 T VE DG V + G E + VL AIG V+ L AGV + Sbjct: 247 KTVPLSVEKQDDGKLLVKYKNVETGEESEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQKD 306 Query: 289 KAIGVDDYMRTNVGHIYAIGDVN-GLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPR 347 K I VD TNV +IYA+GD+ G +L VA G + A + G T + D++ + Sbjct: 307 K-IPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRM-DYKDVAT 364 Query: 348 ATFCQPNVASFGLTEQQARNEG----YDVVVAKFPFTANAKAHGVGDPSGFVKLVADA-K 402 F A GL+E+ A + +V + T ++K VA+ Sbjct: 365 TVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRY-CYLKAVAERHG 423 Query: 403 HGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECF 454 + G H +G E++ A + LT + L V HPT +E Sbjct: 424 DQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLA 475 >1ONF-A nrPDB Length = 500 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 120/498 (24%), Positives = 205/498 (41%), Gaps = 55/498 (11%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61 YD++V+G G GG AA RAA+ A+VE GG C+NVGC+P K + A + H Sbjct: 1 MVYDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMFNAASV-HD 59 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTL 121 ++++ +G + +F+ + +R K + + K+K+ G +F N + Sbjct: 60 ILENSRHYGFDTKFSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLSENRI 119 Query: 122 LVDLNDG---------GTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPK 172 L+ E + N +IA G+ P + N ++ +E +E K Sbjct: 120 LIKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPPVKGI-ENTISSDEFFNIKE-SK 177 Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTA 232 I I G+G I +E V+K G+D I R L D V +E KK + I+T Sbjct: 178 KIGIVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTF 237 Query: 233 TKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIG 292 V I + DG E + V+ +G +P+ E L+K V I Sbjct: 238 ADVVEIKKVSDKNLSIHLSDGRIYE-HFDHVIYCVGRSPDTENLKLEKLNVETN-NNYIV 295 Query: 293 VDDYMRTNVGHIYAIGDVNGL----------------------------------LQLAH 318 VD+ RT+V +IYA+GD + +QL Sbjct: 296 VDENQRTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTP 355 Query: 319 VAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEG--YDVVVAK 376 VA G + A+ + +T +++++P F P + + GL+E+ A +V + + Sbjct: 356 VAINAGRLLADRLFLKKT-RKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIYGKENVKIYE 414 Query: 377 FPFT----ANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLT 432 FT + ++KLV K + G H++G + E++ +A + + T Sbjct: 415 SKFTNLFFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGFAVALKMNAT 474 Query: 433 ASELARNVHTHPTMSEAL 450 + + HPT +E Sbjct: 475 KKDFDETIPIHPTAAEEF 492 >4DNA-A nrPDB Length = 463 Score = 393 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 129/449 (28%), Positives = 204/449 (45%), Gaps = 10/449 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 YD+ V+G G GG + AA LG AI E +GG C+ GC+P K + ++ F Sbjct: 6 YDLFVIGGGSGGVRSGRLAAALGKKVAIAEEFRYGGTCVIRGCVPKKLYVYASQFAEHF- 64 Query: 64 KDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 +DA FG + GE FD+ + + + A NT+ Sbjct: 65 EDAAGFGWTVGESRFDWAKLVAAKEQEIARLEGLYRKGLANAGAEILDTRAELAGPNTVK 124 Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAI 182 + ++VT + +IA G +T E LP+SI+IAG G I Sbjct: 125 LL---ASGKTVTAERIVIAVGGHPSPHDALPGHELCITSNEAFDLPALPESILIAGGGYI 181 Query: 183 GMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESI-ADG 241 +EF + GV T++ L D D+ + + ++ G+ IL ++S+ AD Sbjct: 182 AVEFANIFHGLGVKTTLIYRGKEILSRFDQDMRRGLHAAMEEKGIRILCEDIIQSVSADA 241 Query: 242 GSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNV 301 + T K G E+ A++V+ A+G PN G GL+ AGV + AI VD + RT+ Sbjct: 242 DGRRVATTMKHG---EIVADQVMLALGRMPNTNGLGLEAAGVRTNELGAIIVDAFSRTST 298 Query: 302 GHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLT 361 IYA+GDV +QL VA + + ET T DH ++ A F QP + + G+T Sbjct: 299 PGIYALGDVTDRVQLTPVAIHEAMCFIETEY-KNNPTSPDHDLIATAVFSQPEIGTVGIT 357 Query: 362 EQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLP 421 E++A + ++ V + F +KLV +A +++G H++GHD E+ Sbjct: 358 EEEAARKFQEIEVYRAEFRPMKATLSGRKEKTIMKLVVNAADRKVVGAHILGHDAGEMAQ 417 Query: 422 ELTLAQRWDLTASELARNVHTHPTMSEAL 450 L ++ R T + R + HPT +E L Sbjct: 418 LLGISLRAGCTKDDFDRTMAVHPTAAEEL 446 >4YWO-A nrPDB Length = 462 Score = 381 bits (978), Expect = e-106, Method: Composition-based stats. Identities = 136/454 (29%), Positives = 221/454 (48%), Gaps = 20/454 (4%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 + + ++G G G+ A I+A +LG+ ++ GG C+NVGC+PSK +L AE+ Sbjct: 16 HKLAIIGYGAAGFAAMIKANELGVKPVLIGKGEIGGTCVNVGCVPSKRMLYIAEIYKKAR 75 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV 123 + EV + ++ V E R L+ + I G F + + V Sbjct: 76 EVT-----GSEVYPPFSSFQEKDGLVQEMRKTKYEDLLSYYDVELIQGEARFISPHAVKV 130 Query: 124 DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSA-NVVTYEEQILSRELPKSIIIAGAGAI 182 + + + + +IATGSS + L T E + S+ + G A+ Sbjct: 131 N-----GQVIEAEKFVIATGSSPLIPRIPGLDKVGFWTNREALSPDRRIDSLAVIGGRAL 185 Query: 183 GMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGG 242 +EF + V+V I++ P +P+ + + S E + + GV ++T V+ + G Sbjct: 186 ALEFAQMYSRMKVEVAILQRSPVLIPDWEPEASVEARRIMENDGVAVVTGVNVKEVRKGA 245 Query: 243 SQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVG 302 ++ +T E++A+++L A G PNV+ GL+ AGV L +R I VDD +RT+ Sbjct: 246 GKIVITD-----KGEVEADEILLATGRKPNVD-LGLENAGVRLNERGGIKVDDELRTDNP 299 Query: 303 HIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTE 362 HIYA GDV G L +A QG +A E + D +P+ F QPN+A GLTE Sbjct: 300 HIYAAGDVLGGKMLEALAGRQGSIATENALTG-SHKRVDENAVPQVIFTQPNLARVGLTE 358 Query: 363 QQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPE 422 +AR + +V P ++ AKA + GFVK+V +G ++G H VG +VAE++ E Sbjct: 359 AEARAKEGEVEARVLPMSSVAKAEIINSRLGFVKMVT--MNGRIVGVHAVGENVAEMIGE 416 Query: 423 LTLAQRWDLTASELARNVHTHPTMSEALQECFHG 456 LA R+ T +L VH PT++E+L+ Sbjct: 417 AALAIRFGATVHDLIDTVHMFPTIAESLRLVALA 450 >1ZK7-A nrPDB Length = 467 Score = 366 bits (940), Expect = e-101, Method: Composition-based stats. Identities = 137/453 (30%), Positives = 213/453 (47%), Gaps = 11/453 (2%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKD 65 V V+G+G AA++A + G ++E GG C+NVGC+PSK ++R A + H+ + Sbjct: 7 VAVIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRES 66 Query: 66 AKAFGISGEV-TFDYGIAYDRSR-KVAEGRVAGVHFLMKKN-KITEIHGYGTFADANTLL 122 GI+ V T D + + +V E R A ++ N IT +HG F D +L Sbjct: 67 PFDGGIAATVPTIDRSKLLAQQQARVDELRHAKYEGILGGNPAITVVHGEARFKDDQSLT 126 Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSAN-VVTYEEQILSRELPKSIIIAGAGA 181 V LN+GG V FD ++ATG+S + P L + T E + S +P+ + + G+ Sbjct: 127 VRLNEGGERVVMFDRCLVATGASPAVPPIPGLKESPYWTSTEALASDTIPERLAVIGSSV 186 Query: 182 IGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADG 241 + +E G VT++ ED + + + F+ G+ +L T+ +A Sbjct: 187 VALELAQAFARLGSKVTVLAR-NTLFFREDPAIGEAVTAAFRAEGIEVLEHTQASQVAHM 245 Query: 242 GSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNV 301 + +T T EL+A+K+L A G PN LD AGV + + AI +D MRT+ Sbjct: 246 DGEFVLTTTHG----ELRADKLLVATGRTPNTRSLALDAAGVTVNAQGAIVIDQGMRTSN 301 Query: 302 GHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLT 361 +IYA GD Q +VA A G AA + G + D +P F P VA+ G + Sbjct: 302 PNIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAA--LDLTAMPAVVFTDPQVATVGYS 359 Query: 362 EQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLP 421 E +A ++G + +A D GF+KLV + L+G V + EL+ Sbjct: 360 EAEAHHDGIETDSRTLTLDNVPRALANFDTRGFIKLVIEEGSHRLIGVQAVAPEAGELIQ 419 Query: 422 ELTLAQRWDLTASELARNVHTHPTMSEALQECF 454 LA R +T ELA + + TM E L+ Sbjct: 420 TAALAIRNRMTVQELADQLFPYLTMVEGLKLAA 452 >1OJT-A nrPDB Length = 482 Score = 366 bits (940), Expect = e-101, Method: Composition-based stats. Identities = 158/456 (34%), Positives = 221/456 (48%), Gaps = 14/456 (3%) Query: 16 YVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGE 74 Y AA AA GL AIVE K GGVCLNVGCIPSKALL NA ++ A E Sbjct: 19 YSAAFAAADEGLKVAIVERYKTLGGVCLNVGCIPSKALLHNAAVIDEVRHLAANGIKYPE 78 Query: 75 VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLN-------- 126 D + V G+ + K K+ I G G F D + L V L Sbjct: 79 PELDIDMLRAYKDGVVSRLTGGLAGMAKSRKVDVIQGDGQFLDPHHLEVSLTAGDAYEQA 138 Query: 127 --DGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGM 184 G + V F N IIA GS +P ++ + +E+P ++I G G IG+ Sbjct: 139 APTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALALKEVPGKLLIIGGGIIGL 198 Query: 185 EFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQ 244 E G V G + +VE + + D D+ K +KQ + I+ TK ++ Sbjct: 199 EMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYRFDNIMVNTKTVAVEPKEDG 258 Query: 245 VTVTVTKDGVAQE-LKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGH 303 V VT +E + + VL A G APN + +KAGVA+TDR I VD MRTNV H Sbjct: 259 VYVTFEGANAPKEPQRYDAVLVAAGRAPNGKLISAEKAGVAVTDRGFIEVDKQMRTNVPH 318 Query: 304 IYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQ 363 IYAIGD+ G LAH A +G VAAE AG + D R++P + P VA G TE Sbjct: 319 IYAIGDIVGQPMLAHKAVHEGHVAAENCAGHKAYF--DARVIPGVAYTSPEVAWVGETEL 376 Query: 364 QARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPEL 423 A+ + A FP+ A+ +A G F KL+ DA+ G ++GG +VG + +++ E+ Sbjct: 377 SAKASARKITKANFPWAASGRAIANGCDKPFTKLIFDAETGRIIGGGIVGPNGGDMIGEV 436 Query: 424 TLAQRWDLTASELARNVHTHPTMSEALQECFHGLVG 459 LA A+++ + +H HPT+ E++ +G Sbjct: 437 CLAIEMGCDAADIGKTIHPHPTLGESIGMAAEVALG 472 >5U25-A nrPDB Length = 602 Score = 362 bits (929), Expect = e-100, Method: Composition-based stats. Identities = 160/456 (35%), Positives = 224/456 (49%), Gaps = 14/456 (3%) Query: 16 YVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGE 74 Y AA AA GL AIVE K GGVCLNVGCIPSKALL NA ++ A E Sbjct: 138 YSAAFAAADEGLKVAIVERYKTLGGVCLNVGCIPSKALLHNAAVIDEVRHLAANGIKYPE 197 Query: 75 VTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLN-------- 126 D + V G+ + K K+ I G G F D + L V L Sbjct: 198 PELDIDMLRAYKDGVVSRLTGGLAGMAKSRKVDVIQGDGQFLDPHHLEVSLTAGDAYEQA 257 Query: 127 --DGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGM 184 G + V F N IIA GS +P ++ + +E+P ++I G G IG+ Sbjct: 258 APTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALALKEVPGKLLIIGGGIIGL 317 Query: 185 EFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQ 244 E G V G + +VE + + D D+ K +KQ + I+ TK ++ Sbjct: 318 EMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYRFDNIMVNTKTVAVEPKEDG 377 Query: 245 VTVTVTKDGVAQE-LKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGH 303 V VT +E + + VL A G APN + +KAGVA+TDR I VD MRTNV H Sbjct: 378 VYVTFEGANAPKEPQRYDAVLVAAGRAPNGKLISAEKAGVAVTDRGFIEVDKQMRTNVPH 437 Query: 304 IYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQ 363 IYAIGD+ G LAH A +G VAAE AG + D R++P + P VA G TE Sbjct: 438 IYAIGDIVGQPMLAHKAVHEGHVAAENCAGHKAYF--DARVIPGVAYTSPEVAWVGETEL 495 Query: 364 QARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPEL 423 A+ G + A FP+ A+ +A G +GF KL+ DA+ G ++GG +VG + +++ E+ Sbjct: 496 SAKASGRKITKANFPWAASGRAIANGCDNGFTKLIFDAETGRIIGGGIVGPNGGDMIGEV 555 Query: 424 TLAQRWDLTASELARNVHTHPTMSEALQECFHGLVG 459 LA A+++ + +H HPT+ E++ +G Sbjct: 556 CLAIEMGCDAADIGKTIHPHPTLGESIGMAAEVALG 591 >3IC9-A nrPDB Length = 492 Score = 330 bits (846), Expect = 8e-91, Method: Composition-based stats. Identities = 117/460 (25%), Positives = 189/460 (41%), Gaps = 14/460 (3%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTK 64 DV ++G G G A A + ++E +G C VGC+PSK L+ A+ + + Sbjct: 10 DVAIIGTGTAGMGAYRAAKKHTDKVVLIEGGAYGTTCARVGCMPSKLLIAAADASYHAS- 68 Query: 65 DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAG--VHFLMKKNKITEIHGYGTFADANTLL 122 FGI + G A + + R G V + ++ +I G+ F D +TL Sbjct: 69 QTDLFGIQVDRISVNGKAVMKRIQTERDRFVGFVVESVESFDEQDKIRGFAKFLDEHTLQ 128 Query: 123 VDLNDGGTESVTFDNAIIATGSSTRLVPG-TSLSANVVTYEEQILSRELPKSIIIAGAGA 181 VD + V +IATGS + + ++T + +LPKS+ + G G Sbjct: 129 VDDHS----QVIAKRIVIATGSRPNYPEFLAAAGSRLLTNDNLFELNDLPKSVAVFGPGV 184 Query: 182 IGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADG 241 IG+E G L GV V + +D ++ + EK F + A + +I Sbjct: 185 IGLELGQALSRLGVIVKVFGRSGSVANLQDEEMKRYAEKTFNEEFYFDAKARVISTIEKE 244 Query: 242 GSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDD-YMRTN 300 + + K G + VL A G NV+ GL+ + L + + D+ ++T+ Sbjct: 245 DAVEVIYFDKSGQKTTESFQYVLAATGRKANVDKLGLENTSIELDKKNSPLFDELTLQTS 304 Query: 301 VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL 360 V HI+ GD N L L H A G VA + G R F +P VAS GL Sbjct: 305 VDHIFVAGDANNTLTLLHEAADDGKVAGTNAGAYPVIAQGQRRAPLSVVFTEPQVASVGL 364 Query: 361 TEQQ-----ARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHD 415 + +Q A + + VV + F ++ +G G + + AD GE LG + G Sbjct: 365 SLRQIEDLYADQDAANYVVGQVSFEGQGRSRVMGKNKGLLNVYADRTSGEFLGAEMFGPA 424 Query: 416 VAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFH 455 + L A++ +T + HP + E L+ Sbjct: 425 AEHIGHLLAWARQQQMTVQAMLTMPFYHPVIEEGLRTALR 464 >1XDI-A nrPDB Length = 499 Score = 321 bits (823), Expect = 5e-88, Method: Composition-based stats. Identities = 127/468 (27%), Positives = 207/468 (44%), Gaps = 18/468 (3%) Query: 6 VVVLGAGPGGYVAAIRAAQLGL---STAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 +V+LG GP GY AA+ AA +++ GG + C+PSK + + L Sbjct: 5 IVILGGGPAGYEAALVAATSHPETTQVTVIDCDGIGGAAVLDDCVPSKTFIASTGLRTEL 64 Query: 63 TKDAKAFGISGEVT---FDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADA- 118 + A G + + R + +A + A + + + I G G D+ Sbjct: 65 RR-APHLGFHIDFDDAKISLPQIHARVKTLAAAQSADITAQLLSMGVQVIAGRGELIDST 123 Query: 119 -----NTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGT-SLSANVVTYEEQILSRELPK 172 + + DG T D ++ATG+S R++P ++T+ + LP Sbjct: 124 PGLARHRIKATAADGSTSEHEADVVLVATGASPRILPSAQPDGERILTWRQLYDLDALPD 183 Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTA 232 +I+ G+G G EF GV VT+V LP EDAD + +E+ F + GV + Sbjct: 184 HLIVVGSGVTGAEFVDAYTELGVPVTVVASQDHVLPYEDADAALVLEESFAERGVRLFKN 243 Query: 233 TKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIG 292 + S+ G+ V VT+T + ++ L IG PN G GL++ G+ L + Sbjct: 244 ARAASVTRTGAGVLVTMTD---GRTVEGSHALMTIGSVPNTSGLGLERVGIQLGRGNYLT 300 Query: 293 VDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQ 352 VD RT IYA GD GLL LA VA QG +A G E ++ R + F + Sbjct: 301 VDRVSRTLATGIYAAGDCTGLLPLASVAAMQGRIAMYHALG-EGVSPIRLRTVAATVFTR 359 Query: 353 PNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLV 412 P +A+ G+ + P NA+A GFVK+ G ++GG +V Sbjct: 360 PEIAAVGVPQSVIDAGSVAARTIMLPLRTNARAKMSEMRHGFVKIFCRRSTGVVIGGVVV 419 Query: 413 GHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGH 460 +EL+ + +A + +T +ELA+ + +P++S ++ E L+ H Sbjct: 420 APIASELILPIAVAVQNRITVNELAQTLAVYPSLSGSITEAARRLMAH 467 >3L8K-A nrPDB Length = 466 Score = 312 bits (799), Expect = 2e-85, Method: Composition-based stats. Identities = 132/467 (28%), Positives = 216/467 (46%), Gaps = 23/467 (4%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-YWGGVCLNVGCIPSKALLRNAELVHI 61 YDVVV+GAG GY A R A+ + + +PK GG CL GC+PSK + + Sbjct: 4 KYDVVVIGAGGAGYHGAFRLAKAKYNVLMADPKGELGGNCLYSGCVPSKTVREVIQTAWR 63 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNK-ITEIHGYGTFADANT 120 T A ++ D+ DR V E R M + + +T GY D Sbjct: 64 LTNIAN-----VKIPLDFSTVQDRKDYVQELRFKQHKRNMSQYETLTFYKGYVKIKDPTH 118 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLV--PGTSLSANVVTYEEQI----LSRELPKSI 174 ++V ++G IIA+G+ T + PG +T ++ R+LP+ + Sbjct: 119 VIVKTDEGKEIEAETRYMIIASGAETAKLRLPGVEY---CLTSDDIFGYKTSFRKLPQDM 175 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVSKEIEKQFKKLGVTILTA- 232 +I GAG IG+E + + GV I+E L RAL ED D+ + KL + + Sbjct: 176 VIIGAGYIGLEIASIFRLMGVQTHIIEMLDRALITLEDQDIVNTLLSIL-KLNIKFNSPV 234 Query: 233 TKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIG 292 T+V+ I D +V + TKDG + + V+ A G P + G + G++++ I Sbjct: 235 TEVKKIKDDEYEV-IYSTKDGSKKSIFTNSVVLAAGRRPVIPE-GAREIGLSISKTG-IV 291 Query: 293 VDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETI-AGAETLTLGDHRMLPRATFC 351 VD+ M+TN+ +++A GD NGL H A + AA I A + D + +P + Sbjct: 292 VDETMKTNIPNVFATGDANGLAPYYHAAVRMSIAAANNIMANGMPVDYVDVKSIPVTIYT 351 Query: 352 QPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHL 411 P+++ G+ +AR G ++V A++ + A G G +KL+ + L+G + Sbjct: 352 IPSLSYVGILPSKARKMGIEIVEAEYNMEEDVSAQIYGQKEGVLKLIFERGSMRLIGAWM 411 Query: 412 VGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLV 458 +G L+ EL LA + L A +LA HP+ +E + ++ Sbjct: 412 IGVHSQYLINELGLAVAYGLNAKQLASFAEQHPSTNEIISYTARKVI 458 >3Q6J-A nrPDB Length = 523 Score = 269 bits (688), Expect = 2e-72, Method: Composition-based stats. Identities = 100/484 (20%), Positives = 179/484 (36%), Gaps = 60/484 (12%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVH 60 YD + +G G G + +G IV+ + GG C + C+P H Sbjct: 42 REYDAIFIGGGAAGRFGSAYLRAMGGRQLIVDRWPFLGGSCPHNACVPH----------H 91 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGY-------- 112 +F+ A ++ + Y D + KV + F +N I + Sbjct: 92 LFSDCAAELMLARTFSGQYWF-PDMTEKVVGIKEVVDLFRAGRNGPHGIMNFQSKEQLNL 150 Query: 113 -------GTFADANTLLVDLNDGGTESVTFDNAIIATGSST--RLVPGTSLSANVVTYEE 163 D +T+ + N I+A G+ VPG + Sbjct: 151 EYILNCPAKVIDNHTVE-----AAGKVFKAKNLILAVGAGPGTLDVPGVNAKGVFDHATL 205 Query: 164 QILSRELPKS-IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQF 222 P S +++ G +E+G G ++ +D + + + Sbjct: 206 VEELDYEPGSTVVVVGGSKTAVEYGCFFNATGRRTVMLVRTEPLKLIKDNETRAYVLDRM 265 Query: 223 KKLGVTILTATKVESIADGGS---QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLD 279 K+ G+ I++ + V I + + Q V +T +G + ++ + V +G P Sbjct: 266 KEQGMEIISGSNVTRIEEDANGRVQAVVAMTPNGEMR-IETDFVFLGLGEQPRSAELAKI 324 Query: 280 KAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTL 339 G+ L + + V++Y++T+V ++YA+GD+ G A G AA + G + Sbjct: 325 -LGLDLGPKGEVLVNEYLQTSVPNVYAVGDLIGGPMEMFKARKSGCYAARNVMGEKISY- 382 Query: 340 GDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPF-TANA--------------- 383 + P V+ G+ E++AR G+++V K P T N Sbjct: 383 -TPKNYPDFLHTHYEVSFLGMGEEEARAAGHEIVTIKMPPDTENGLNVALPASDRTMLYA 441 Query: 384 KAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARN--VH 441 G SGF K+V DAK ++LG H VG+ + L + + LT EL + Sbjct: 442 FGKGTAHMSGFQKIVIDAKTRKVLGAHHVGYGAKDAFQYLNVLIKQGLTVDELGDMDELF 501 Query: 442 THPT 445 +PT Sbjct: 502 LNPT 505 >5ER0-A nrPDB Length = 518 Score = 227 bits (580), Expect = 7e-60, Method: Composition-based stats. Identities = 86/343 (25%), Positives = 145/343 (42%), Gaps = 29/343 (8%) Query: 117 DANTLLV-DLNDGGTESVTFDNAIIATGSSTR--LVPGTS-----LSANVVTYEEQILSR 168 D T+ V DL + + ++D ++ +GS +PG L N + I Sbjct: 135 DQKTVTVEDLTNHAQTTESYDKLVMTSGSWPIVPKIPGIDSDRVKLCKNWAHAQALIEDA 194 Query: 169 ELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVSKEIEKQFKKLGV 227 + K I + GAG IG E G DVT+++ + R +P DAD + IE+ ++ GV Sbjct: 195 KEAKRITVIGAGYIGAELAEAYSTTGHDVTLIDAMARVMPKYFDADFTDVIEQDYRDHGV 254 Query: 228 TILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 + VES D + +T+ K+ + + + IGF PN + K V + Sbjct: 255 QLALGETVESFTDSATGLTIKTDKN----SYETDLAILCIGFRPNTDLL---KGKVDMAP 307 Query: 288 RKAIGVDDYMRTNVGHIYAIGDV----------NGLLQLAHVAEAQGVVAAETIAGAETL 337 AI DDYMR++ I+A GD N + LA A QG++ + + Sbjct: 308 NGAIITDDYMRSSNPDIFAAGDSAAVHYNPTHQNAYIPLATNAVRQGILVGKNLVKPTVK 367 Query: 338 TLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKL 397 +G A + + + S GLT A+ +G + + +P + L Sbjct: 368 YMGTQSSSGLALYDR-TIVSTGLTLAAAKQQGLNAEQVIVEDNYRPEFMPSTEPV-LMSL 425 Query: 398 VADAKHGELLGGHLVG-HDVAELLPELTLAQRWDLTASELARN 439 V D +LGG L+ +DV++ L++ + + T +LA Sbjct: 426 VFDPDTHRILGGALMSKYDVSQSANTLSVCIQNENTIDDLAMV 468 >2BC1-A nrPDB Length = 490 Score = 227 bits (579), Expect = 9e-60, Method: Composition-based stats. Identities = 83/355 (23%), Positives = 143/355 (40%), Gaps = 41/355 (11%) Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLVP--GTSLSANVVTYEE----------- 163 DA T+ L DG T+D I ATGS L P G + + +E Sbjct: 121 DAKTVTA-LVDGKNHVETYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLY 179 Query: 164 -------QILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVS 215 L + K + + GAG IG+E + G +V +++ + L D D++ Sbjct: 180 QNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLT 239 Query: 216 KEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEG 275 + K ++ G+ + V+ +A G + K+ E + V+ A+GF PN Sbjct: 240 DLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKN----EYDVDMVILAVGFRPNTT- 294 Query: 276 YGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDV----------NGLLQLAHVAEAQGV 325 L + L A V+ T++ +YAIGD + LA A G+ Sbjct: 295 --LGNGKIDLFRNGAFLVNKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGI 352 Query: 326 VAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKA 385 VAA G + +G + + ++ S GLT ++A+ G+D V ++ + Sbjct: 353 VAAHNACGTDLEGIGVQGSNGISIYG-LHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEF 411 Query: 386 HGVGDPSGFVKLVADAKHGELLGGHLVG-HDVAELLPELTLAQRWDLTASELARN 439 G+ +K+V D +LG + DV+ + +LA + +T +LA Sbjct: 412 IEHGNFPVTIKIVYDKDSRRILGAQMAAREDVSMGIHMFSLAIQEGVTIEKLALT 466 >3CGD-A nrPDB Length = 480 Score = 217 bits (553), Expect = 8e-57, Method: Composition-based stats. Identities = 93/453 (20%), Positives = 160/453 (35%), Gaps = 59/453 (13%) Query: 6 VVVLGAGPGGYVAAIRAAQL--GLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 V++G G AA++ + + +E G I S A ++ Sbjct: 39 YVIIGGDAAGMSAAMQIVRNDENANVVTLEK----------GEIYSYAQCGLPYVISGAI 88 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV 123 + TF D + ++T++ A Sbjct: 89 ASTEKLIARNVKTFRDKYGIDAKVRH---------------EVTKVDTEKKIVYAEHTKT 133 Query: 124 DLNDGGTESVTFDNAIIATGSST-------RLVPGTSLSANVVTYEEQILSRELPK--SI 174 ++D +IATG R + G L + E + + E K + Sbjct: 134 K----DVFEFSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDV 189 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATK 234 I G GAIG+E G V ++E D D+++ I K+ K + ILT Sbjct: 190 TIIGGGAIGLEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHHIEILTNEN 249 Query: 235 VESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVD 294 V++ G +V T G KA+ VL ++G PN + L+ + + AI V+ Sbjct: 250 VKAFK-GNERVEAVETDKG---TYKADLVLVSVGVKPNTDF--LEGTNIRTNHKGAIEVN 303 Query: 295 DYMRTNVGHIYAIGDVN----------GLLQLAHVAEAQGVVAAETIAGAETLTLGDHRM 344 YM+TNV +YA GD + + A QG +A + G Sbjct: 304 AYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAGLNMLDKRRAFKGTLGT 363 Query: 345 LPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHG 404 F +A GL E++A+ K T A + ++KL+ + Sbjct: 364 -GIIKFMNLTLARTGLNEKEAKGLHIPYKTVKVDSTNMA-GYYPNAKPLYLKLLYRSDTK 421 Query: 405 ELLGGHLVG-HDVAELLPELTLAQRWDLTASEL 436 +LLGG ++G V + + + +A ++ +L Sbjct: 422 QLLGGQVIGEEGVDKRIDVIAMALFNKMSIHDL 454 Score = 36.0 bits (82), Expect = 0.033, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 23/68 (33%), Gaps = 12/68 (17%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTK 64 DV ++G G G A +LG ++E G + + ++ K Sbjct: 188 DVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIGT------------IYDGDMAEYIYK 235 Query: 65 DAKAFGIS 72 +A I Sbjct: 236 EADKHHIE 243 >3ICS-A nrPDB Length = 588 Score = 213 bits (542), Expect = 2e-55, Method: Composition-based stats. Identities = 74/355 (20%), Positives = 148/355 (41%), Gaps = 35/355 (9%) Query: 104 NKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTY 161 +++ +I+ + + T + +D I++ G+ + +PG + + T Sbjct: 114 SEVVKINKEEKTITIKNVTTN----ETYNEAYDVLILSPGAKPIVPSIPGIEEAKALFTL 169 Query: 162 E--------EQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDAD 213 + + + P+ + G G IG+E L+ G++VT+VE + +P D + Sbjct: 170 RNVPDTDRIKAYIDEKKPRHATVIGGGFIGVEMVENLRERGIEVTLVEMANQVMPPIDYE 229 Query: 214 VSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNV 273 ++ + + K V ++ V+++ + G+ V + ++ + ++ AIG P Sbjct: 230 MAAYVHEHMKNHDVELVFEDGVDALEENGAVVRLK-----SGSVIQTDMLILAIGVQP-- 282 Query: 274 EGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNG----------LLQLAHVAEAQ 323 E AG+AL R I V++ +T+ HIYAIGD ++ LA A Q Sbjct: 283 ESSLAKGAGLALGVRGTIKVNEKFQTSDPHIYAIGDAIEVKDFVTETETMIPLAWPANRQ 342 Query: 324 GVVAAETIAGA-ETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTAN 382 G + A+ I G ++L G F VA+ GL E+ + V + Sbjct: 343 GRMLADIIHGHTDSLYKGTLGTSVAKVF-DLTVATTGLNEKILKRLNIPYEVVHVQ-ANS 400 Query: 383 AKAHGVGDPSGFVKLVADAKHGELLGGHLVG-HDVAELLPELTLAQRWDLTASEL 436 + +KL+ + G++ G +G V + + + A + +LT +L Sbjct: 401 HAGYYPNATPVLIKLIFNKDSGKIYGAQTLGRDGVDKRMDVIATAIKANLTVLDL 455 >3NTA-A nrPDB Length = 574 Score = 211 bits (537), Expect = 6e-55, Method: Composition-based stats. Identities = 79/373 (21%), Positives = 143/373 (38%), Gaps = 50/373 (13%) Query: 103 KNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYE 162 K+++ I LL DG ++D +++ G++ + P + + Sbjct: 78 KHEVVAIDRAAKLVTVRRLL----DGSEYQESYDTLLLSPGAAPIVPPIPGVDNPLTHSL 133 Query: 163 EQILSRE---------LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDAD 213 I + + + G G IG+E L + G+ T++E + + D + Sbjct: 134 RNIPDMDRILQTIQMNNVEHATVVGGGFIGLEMMESLHHLGIKTTLLELADQVMTPVDRE 193 Query: 214 VSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQE---------------- 257 ++ + + GV + T + + QV V D ++ Sbjct: 194 MAGFAHQAIRDQGVDLRLGTALSEV---SYQVQTHVASDAAGEDTAHQHIKGHLSLTLSN 250 Query: 258 ---LKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGD----- 309 L+ + ++ AIG P + AG+A+ + I V+ M+T+ IYA+GD Sbjct: 251 GELLETDLLIMAIGVRPETQ--LARDAGLAIGELGGIKVNAMMQTSDPAIYAVGDAVEEQ 308 Query: 310 --VNG---LLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQ 364 V G L+ LA A QG +AA+ + G E G F V + G E+Q Sbjct: 309 DFVTGQACLVPLAGPANRQGRMAADNMFGREERYQGTQGTAICKVF-DLAVGATGKNEKQ 367 Query: 365 ARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDV-AELLPEL 423 + G + TA+ ++ G KL+ D G + G VG D + + + Sbjct: 368 LKQAGI-AFEKVYVHTASHASYYPGAEVVSFKLLFDPVKGTIFGAQAVGKDGIDKRIDVM 426 Query: 424 TLAQRWDLTASEL 436 +AQR +T +L Sbjct: 427 AVAQRAGMTVEQL 439 >1NHQ-A nrPDB Length = 447 Score = 210 bits (535), Expect = 9e-55, Method: Composition-based stats. Identities = 78/342 (22%), Positives = 131/342 (38%), Gaps = 31/342 (9%) Query: 118 ANTLLV-DLNDGGTESVTFDNAIIATGSST--RLVPGTSLSANVVTYEEQILSRELPK-- 172 + + V DL G +D II+ G+ +PG L + Q + K Sbjct: 86 EHQVTVKDLVSGEERVENYDKLIISPGAVPFELDIPGKDLDNIYLMRGRQWAIKLKQKTV 145 Query: 173 -----SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNE-DADVSKEIEKQFKKLG 226 ++++ G+G IG+E G VT+++ L R L D + + + ++ + Sbjct: 146 DPEVNNVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDRPLGVYLDKEFTDVLTEEMEANN 205 Query: 227 VTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALT 286 +TI T VE G V K+ A+ V+ A+G PN K + L Sbjct: 206 ITIATGETVERYEGDGRVQKVVTDKNA----YDADLVVVAVGVRPNTAWL---KGTLELH 258 Query: 287 DRKAIGVDDYMRTNVGHIYAIGDVNGL----------LQLAHVAEAQGVVAAETIAGAET 336 I D+YMRT+ ++A+GD + + LA A QG A + + Sbjct: 259 PNGLIKTDEYMRTSEPDVFAVGDATLIKYNPADTEVNIALATNARKQGRFAVKNLEEPVK 318 Query: 337 LTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVK 396 G A F AS G+ E A+ G + + K Sbjct: 319 PFPGVQGSSGLAVF-DYKFASTGINEVMAQKLGKETKAVTVVEDYLMDF-NPDKQKAWFK 376 Query: 397 LVADAKHGELLGGHLVGH-DVAELLPELTLAQRWDLTASELA 437 LV D + ++LG L+ D+ + ++LA + +T +LA Sbjct: 377 LVYDPETTQILGAQLMSKADLTANINAISLAIQAKMTIEDLA 418 Score = 44.9 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 40/213 (18%), Positives = 77/213 (36%), Gaps = 36/213 (16%) Query: 173 SIIIAG---AGAIGMEFGYVLKNYGV-----DVTIVEFLPRALPNE------DADVSKEI 218 +I+ G G +E L + FL + D + + + Sbjct: 2 KVIVLGSSHGGYEAVEELLNLHPDAEIQWYEKGDFISFLSSGMQLYLEGKVKDVNSVRYM 61 Query: 219 E-KQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAP---NVE 274 ++ + GV + + T++ +I QVTV G + +K++ + G P ++ Sbjct: 62 TGEKMESRGVNVFSNTEITAIQPKEHQVTVKDLVSGEERVENYDKLIISPGAVPFELDIP 121 Query: 275 GYGLDKAGVALTDRKAIGVDDYMRTNVG---HIYAIGDVNGLLQLAHVAEAQGVVAAETI 331 G LD + + AI + +T ++ IG +G + G+ AAE Sbjct: 122 GKDLDNIYLMRGRQWAIKL--KQKTVDPEVNNVVVIG--SGYI---------GIEAAEAF 168 Query: 332 A-GAETLTLGDHRMLPRATFCQPNVASFGLTEQ 363 A + +T+ D P + LTE+ Sbjct: 169 AKAGKKVTVIDILDRPLGVYLDKEFTDV-LTEE 200 Score = 34.9 bits (79), Expect = 0.080, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 16/28 (57%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 VVV+G+G G AA A+ G +++ Sbjct: 152 VVVIGSGYIGIEAAEAFAKAGKKVTVID 179 >1YQZ-A nrPDB Length = 438 Score = 200 bits (508), Expect = 1e-51, Method: Composition-based stats. Identities = 73/355 (20%), Positives = 136/355 (38%), Gaps = 33/355 (9%) Query: 102 KKNKITEIHGYGTFADANTLLVDLNDGGTESVT--FDNAIIATGSSTRLVPGTSLSANVV 159 K+ + H D + LN E +D I++ G+S + G Sbjct: 71 KQITVKTYHEVIAINDERQTVSVLNRKTNEQFEESYDKLILSPGASANSL-GFESDITFT 129 Query: 160 TYE-------EQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDA 212 +Q + +++ GAG + +E L G+ T++ + DA Sbjct: 130 LRNLEDTDAIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDA 189 Query: 213 DVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPN 272 D+++ I + K + ++ +I G+++T K G + + +++ +G PN Sbjct: 190 DMNQPILDELDKREIPYRLNEEINAI--NGNEITF---KSGKVEH--YDMIIEGVGTHPN 242 Query: 273 VEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDV----------NGLLQLAHVAEA 322 + + + + L + I V+D TNV +IYAIGD+ + LA A Sbjct: 243 SKFI--ESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHR 300 Query: 323 QGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTAN 382 + AE IAG +T+ F AS G+ + + Y +V AN Sbjct: 301 AASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHAN 360 Query: 383 AKAHGVGDPSGFVKLVADAKHGELLGGHLVG-HDVAELLPELTLAQRWDLTASEL 436 G+ +++ D + ++L VG + + L++A LT EL Sbjct: 361 Y---YPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDEL 412 >3IWA-A nrPDB Length = 472 Score = 199 bits (507), Expect = 2e-51, Method: Composition-based stats. Identities = 82/358 (22%), Positives = 137/358 (38%), Gaps = 32/358 (8%) Query: 106 ITEIHGYGTFADANTLLVD-LNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQ 164 + E + A+T+ ++ L G ++ +D ++A GS P + VT Sbjct: 84 LVETRAHAIDRAAHTVEIENLRTGERRTLKYDKLVLALGSKANRPPVEGMDLAGVTPVTN 143 Query: 165 ILSRELPK---------SIIIAGAGAIGMEFGYVLKNY-GVDVTIVEFLPRALPNED-AD 213 + E + +I G G IG+E L + G+D T+VE + +P Sbjct: 144 LDEAEFVQHAISAGEVSKAVIVGGGFIGLEMAVSLADMWGIDTTVVELADQIMPGFTSKS 203 Query: 214 VSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNV 273 +S+ + +K V + T KV + +V +T + L A+ V+ A G +PN Sbjct: 204 LSQMLRHDLEKNDVVVHTGEKVVRLEGENGKVARVITD---KRTLDADLVILAAGVSPNT 260 Query: 274 EGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVN----------GLLQLAHVAEAQ 323 + AG+ L R AI VD MRT+ I+A GD G L +A Q Sbjct: 261 Q--LARDAGLELDPRGAIIVDTRMRTSDPDIFAGGDCVTIPNLVTGKPGFFPLGSMANRQ 318 Query: 324 GVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANA 383 G V +A + G F + + + GLT + A EGYD V A Sbjct: 319 GRVIGTNLADGDATFPGAVGSWAVKLF-EGSASGAGLTVEGALREGYDAVNVHVEQFDRA 377 Query: 384 KAHGVGDPSGFVKLVADAKHGELLGGHL---VGHDVAELLPELTLAQRWDLTASELAR 438 + ++LV D +LG +G + + + T +++ Sbjct: 378 HFY-PEKTIMTLQLVVDRPTRRVLGIQGFSTLGDALTARINAVATMLASKPTVEDISN 434 Score = 35.6 bits (81), Expect = 0.051, Method: Composition-based stats. Identities = 31/138 (22%), Positives = 51/138 (36%), Gaps = 27/138 (19%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYG--VDVTIVEFLPRA--------------------LPN 209 K +++ GA A+G + K VT+++ R L Sbjct: 4 KHVVVIGAVALGPKAACRFKRLDPEAHVTMIDQASRISYGGCGIPYYVSGEVSNIESLQA 63 Query: 210 EDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGF 269 +V ++ E V L T+ +I V + + G + LK +K++ A+G Sbjct: 64 TPYNVVRDPEFFRINKDVEALVETRAHAIDRAAHTVEIENLRTGERRTLKYDKLVLALGS 123 Query: 270 ---APNVEGYGLDKAGVA 284 P VEG L AGV Sbjct: 124 KANRPPVEGMDL--AGVT 139 >2CDU-A nrPDB Length = 452 Score = 198 bits (503), Expect = 5e-51, Method: Composition-based stats. Identities = 79/347 (22%), Positives = 142/347 (40%), Gaps = 32/347 (9%) Query: 116 ADANTLLVDLND---GGTESVTFDNAIIATGSSTRLVPGTSLSANVVT-----YEEQILS 167 D T + + D ++ +D I+ TGS + P + ++ V + + L Sbjct: 84 VDPETKTIKVKDLITNEEKTEAYDKLIMTTGSKPTVPPIPGIDSSRVYLCKNYNDAKKLF 143 Query: 168 RELPK--SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVSKEIEKQFKK 224 E PK +I I G+G IG E N +V +++ R L D + + + K ++ Sbjct: 144 EEAPKAKTITIIGSGYIGAELAEAYSNQNYNVNLIDGHERVLYKYFDKEFTDILAKDYEA 203 Query: 225 LGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVA 284 GV ++ +KV + + ++ +E+K++ + IGF PN E K VA Sbjct: 204 HGVNLVLGSKVAAFEEVDDEIITKTLD---GKEIKSDIAILCIGFRPNTELL---KGKVA 257 Query: 285 LTDRKAIGVDDYMRTNVGHIYAIGD----------VNGLLQLAHVAEAQGVVAAETIAGA 334 + D AI D+YM ++ I+A GD N + LA A QG + + Sbjct: 258 MLDNGAIITDEYMHSSNRDIFAAGDSAAVHYNPTNSNAYIPLATNAVRQGRLVGLNLTED 317 Query: 335 ETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDP-SG 393 + +G + + S G+ A+ ++ V++ N + + Sbjct: 318 KVKDMGTQSSSGLKLYGR-TYVSTGINTALAKAN--NLKVSEVIIADNYRPEFMLSTDEV 374 Query: 394 FVKLVADAKHGELLGGHLVG-HDVAELLPELTLAQRWDLTASELARN 439 + LV D K +LGG L HDV++ L++ + T +LA Sbjct: 375 LMSLVYDPKTRVILGGALSSMHDVSQSANVLSVCIQNKNTIDDLAMV 421 >4FX9-A nrPDB Length = 453 Score = 192 bits (489), Expect = 2e-49, Method: Composition-based stats. Identities = 93/359 (25%), Positives = 147/359 (40%), Gaps = 31/359 (8%) Query: 98 HFLMKKNKIT-EIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSA 156 +KK I ++ D + V N GG +S +D + A G+S ++ ++ Sbjct: 69 EVFIKKRGIDLHLNAEVIEVDTGYVRVREN-GGEKSYEWDYLVFANGASPQVPAIEGVNL 127 Query: 157 NVVTYEE---------QILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRAL 207 V + + + + ++++I G G IG+E G +VT++ R L Sbjct: 128 KGVFTADLPPDALAIREYMEKYKVENVVIIGGGYIGIEMAEAFAAQGKNVTMIVRGERVL 187 Query: 208 PN-EDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQA 266 D +V+ +E++ KK V + I G +V VT G E KAE V+ A Sbjct: 188 RRSFDKEVTDILEEKLKKH-VNLRLQEITMKIE-GEERVEKVVTDAG---EYKAELVILA 242 Query: 267 IGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNG----------LLQL 316 G PN+E + GV + + AI ++ M+T+V ++YA GDV + L Sbjct: 243 TGIKPNIE--LAKQLGVRIGETGAIWTNEKMQTSVENVYAAGDVAETRHVITGRRVWVPL 300 Query: 317 AHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAK 376 A G VA IAG E G F + GLTE +A EGYDV A Sbjct: 301 APAGNKMGYVAGSNIAGKELHFPGVLGT-AVTKFMDVEIGKTGLTEMEALKEGYDVRTA- 358 Query: 377 FPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASE 435 F + + G ++K V D + LLG +VG D+ + T + Sbjct: 359 FIKASTRPHYYPGGREIWLKGVVDNETNRLLGVQVVGSDILPRIDTAAAMLMAGFTTKD 417 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 54/149 (36%), Gaps = 22/149 (14%) Query: 168 RELPKSIIIAGAGAIGMEFGYVLKNYGVD--VTIVEFLPRA-------------LPNEDA 212 + K ++I G GA GM +K + V + E L D Sbjct: 3 ENMKKKVVIIGGGAAGMSAASRVKRLKPEWDVKVFEATEWVSHAPCGIPYVVEGLSTPDK 62 Query: 213 DVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPN 272 + E KK G+ + +V + G +V ++G + + + ++ A G +P Sbjct: 63 LMYYPPEVFIKKRGIDLHLNAEVIEVDTGYVRVR----ENGGEKSYEWDYLVFANGASPQ 118 Query: 273 V---EGYGLDKAGVALTDRKAIGVDDYMR 298 V EG L A A+ + +YM Sbjct: 119 VPAIEGVNLKGVFTADLPPDALAIREYME 147 >4GCM-A nrPDB Length = 312 Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 82/341 (24%), Positives = 132/341 (38%), Gaps = 57/341 (16%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLN---VGCIPSKALLRNAELVH 60 +D+ ++GAGP G AA+ A++ L T ++E GG N V P ++ +L Sbjct: 7 FDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLST 66 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 + AK FG + + I + G + Sbjct: 67 KMFEHAKKFG----------------------------AVYQYGDIKSVEDKGEY----- 93 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLV--PGT-SLSANVVTYEEQILSRELP-KSIII 176 + + G + +T IIATG+ + + PG L V+Y K + + Sbjct: 94 ---KVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFV 150 Query: 177 AGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVE 236 G G +E G L + VTIV ++ FK + + + ++ Sbjct: 151 IGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQ-----DRAFKNDKIDFIWSHTLK 205 Query: 237 SIADGGSQ---VTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 SI + + VT+T TKDG + +A+ V IG P + G+ D I Sbjct: 206 SINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPF--KDLGI-TNDVGYIVT 262 Query: 294 DDYMRTNVGHIYAIGDVN--GLLQLAHVAEAQGVVAAETIA 332 D M T+V I+A GDV GL Q+ A G +AA++ A Sbjct: 263 KDDMTTSVPGIFAAGDVRDKGLRQIV-TATGDGSIAAQSAA 302 >5MJK-A nrPDB Length = 327 Score = 186 bits (473), Expect = 1e-47, Method: Composition-based stats. Identities = 72/343 (20%), Positives = 124/343 (36%), Gaps = 57/343 (16%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCI---PSKALLRNAEL 58 YDVV++G+GP G AA+ A+ + T ++E GG N I P + EL Sbjct: 23 KKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMGPEL 82 Query: 59 VHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADA 118 + + G+ F +T I +G D Sbjct: 83 SMKMAEPLEGLGVENAYGF----------------------------VTGIEDHG---DY 111 Query: 119 NTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILSRELPKS--I 174 ++ + ++ T + IIATG++ R +PG + ++ I Sbjct: 112 KKIITEDDEFIT-----KSIIIATGANHRKLEIPGEEEYGARGVSYCAVCDGAFFRNQEI 166 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATK 234 ++ G G +E L +G VTI+ + ++ + ++ FK+ + + + Sbjct: 167 LVIGGGDSAVEEALYLTRFGQSVTIMHRRDKLRA---QEIIQ--QRAFKEEKINFIWDSV 221 Query: 235 VESIADGGSQ---VTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAI 291 I + V K G E + +G P E G+ + I Sbjct: 222 PMEIKGDDKKIQSVVYKNVKTGEVTEKAFGGIFIYVGLDPVAEFVS--DLGI-TDEAGWI 278 Query: 292 GVDDYMRTNVGHIYAIGDVN--GLLQLAHVAEAQGVVAAETIA 332 DD+MRTN+ I+A+GDV Q+ A G AA+ Sbjct: 279 ITDDHMRTNIPGIFAVGDVRQKDFRQIT-TAVGDGAQAAQEAY 320 >2Q7V-A nrPDB Length = 325 Score = 184 bits (467), Expect = 8e-47, Method: Composition-based stats. Identities = 83/341 (24%), Positives = 124/341 (36%), Gaps = 61/341 (17%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGV------CLNVGCIPSKALLRNAE 57 YDVV++G GP G AAI + LST I+E GG N P + E Sbjct: 9 YDVVIIGGGPAGLTAAIYTGRAQLSTLILEKGMPGGQIAWSEEVENFPGFPEP--IAGME 66 Query: 58 LVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFAD 117 L + A+ FG E+ G+ +D + V G + Sbjct: 67 LAQRMHQQAEKFGAKVEMDEVQGVQHDATSHPYPFTVRGYNG------------------ 108 Query: 118 ANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTS----LSANVVTYEEQILSRELP 171 I+ATG+ R +PG + + + Sbjct: 109 --------------EYRAKAVILATGADPRKLGIPGEDNFWGKGVSTCATCDGFFYK--G 152 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 K +++ G G +E G L + +VT++ N+ A + F + + Sbjct: 153 KKVVVIGGGDAAVEEGMFLTKFADEVTVIHRRDTLRANKVAQA-----RAFANPKMKFIW 207 Query: 232 ATKVESI--ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRK 289 T VE I AD S V + K G EL + V IG PN K V+L D Sbjct: 208 DTAVEEIQGADSVSGVKLRNLKTGEVSELATDGVFIFIGHVPNT---AFVKDTVSLRDDG 264 Query: 290 AIGVDDYMRTNVGHIYAIGDVNGLL--QLAHVAEAQGVVAA 328 + V D + TN+ ++A GDV+ + QLA + G AA Sbjct: 265 YVDVRDEIYTNIPMLFAAGDVSDYIYRQLA-TSVGAGTRAA 304 >5UWY-A nrPDB Length = 308 Score = 183 bits (465), Expect = 1e-46, Method: Composition-based stats. Identities = 73/342 (21%), Positives = 123/342 (35%), Gaps = 59/342 (17%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 YD +++G+GP G AA+ AA+ LS AI+E GG N Sbjct: 5 YDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNT------------------- 45 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHG----YGTFADAN 119 F I +D+ + + K+ E ++K + I+G F D Sbjct: 46 -----FDIENYPGYDHISGPELAMKMYEP--------LEKFNVENIYGIVQKIENFGDYK 92 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRLV--PGTSLSANVVTYEEQILSREL--PKSII 175 +L + IIATG+ R++ PG + + + ++ Sbjct: 93 CVLTEDAS-----YEAKTVIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLL 147 Query: 176 IAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKV 235 + G G +E L + VT+V + + ++ F V + + V Sbjct: 148 VVGGGDSAVEEAIYLTQFAKKVTVVHRRDQLRAQKILQ-----DRAFANDKVDFIWDSVV 202 Query: 236 ESIADGGSQ---VTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIG 292 + I + V + K G + V +G P G+ K I Sbjct: 203 KEIQGNDIKVSNVLIENVKTGQVTDHAFGGVFIYVGMNPVT---GMVKDLEITDSEGWII 259 Query: 293 VDDYMRTNVGHIYAIGDVN--GLLQLAHVAEAQGVVAAETIA 332 DD+MRT++ I+AIGDV L Q+ A G +A + + Sbjct: 260 TDDHMRTSIPGIFAIGDVRQKDLRQIT-TAVGDGAIAGQGVY 300 >3OC4-A nrPDB Length = 452 Score = 176 bits (446), Expect = 2e-44, Method: Composition-based stats. Identities = 82/452 (18%), Positives = 154/452 (34%), Gaps = 64/452 (14%) Query: 6 VVVLGAGPGGYVAAIRAAQL--GLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 +V++GA G AAI + + ++++ + VG Sbjct: 5 IVIIGASFAGISAAIASRKKYPQAEISLIDKQA------TVG------------------ 40 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV 123 + G+S ++ E L+ ++ + N L+ Sbjct: 41 --YLSGGLSAYFNHTINELHEARYITEEELRRQKIQLLLNREVVAMD------VENQLIA 92 Query: 124 DLNDGGTESVTFDNAIIATGSS--TRLVPGTS---LSANVVTYEEQILSR--ELPKSIII 176 + ++D I+ATG+S + + G+ L E +++ + Sbjct: 93 WTRKEEQQWYSYDKLILATGASQFSTQIRGSQTEKLLKYKFLSGALAAVPLLENSQTVAV 152 Query: 177 AGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVSKEIEKQFKKLGVTILTATKV 235 GAG IGME L V + E L LP D ++ E++K +K V V Sbjct: 153 IGAGPIGMEAIDFLVKMKKTVHVFESLENLLPKYFDKEMVAEVQKSLEKQAVIFHFEETV 212 Query: 236 ESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDD 295 I + + + + ++ QE+ + + A+ P + + + I VD Sbjct: 213 LGIEETANGIVLETSE----QEISCDSGIFALNLHPQLAYL---DKKIQRNLDQTIAVDA 265 Query: 296 YMRTNVGHIYAIGDV----------NGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRML 345 Y++T+V +++AIGD L + A G+V A + +G R + Sbjct: 266 YLQTSVPNVFAIGDCISVMNEPVAETFYAPLVNNAVRTGLVVANNLEEKTHRFIGSLRTM 325 Query: 346 PRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGE 405 +AS GLTE + + KL+ D Sbjct: 326 GTKV-GDYYLASTGLTETEGLFFPQTLASIIVR---QPAPPLQHGTEILGKLIYDKVTQR 381 Query: 406 LLGGHLVGH-DVAELLPELTLAQRWDLTASEL 436 +LG L + E + L L+ + T ++L Sbjct: 382 VLGAQLCSKNNCLEKINTLALSIQTGQTLTDL 413 Score = 32.2 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 14/111 (12%), Positives = 36/111 (32%), Gaps = 17/111 (15%) Query: 173 SIIIAGAGAIGMEFGYV---------LKNYGVDVTIVEFLPRALPNEDADVSKE------ 217 I+I GA G+ + T+ + +++ Sbjct: 4 KIVIIGASFAGISAAIASRKKYPQAEISLIDKQATVGYLSGGLSAYFNHTINELHEARYI 63 Query: 218 IEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIG 268 E++ ++ + +L +V ++ + T + Q +K++ A G Sbjct: 64 TEEELRRQKIQLLLNREVVAMDVENQLIAWTRKE--EQQWYSYDKLILATG 112 >3F8P-A nrPDB Length = 323 Score = 173 bits (438), Expect = 2e-43, Method: Composition-based stats. Identities = 75/345 (21%), Positives = 130/345 (37%), Gaps = 61/345 (17%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKAL---LRNAELV 59 +DV+++G GP Y AA+ +A+ L T ++ + GG G + ++ ++++ Sbjct: 15 KFDVIIVGLGPAAYGAALYSARYMLKTLVI-GETPGGQLTEAGIVDDYLGLIEIQASDMI 73 Query: 60 HIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADAN 119 +F K + + + + D K+ G F++K + E Sbjct: 74 KVFNKHIEKY--------EVPVLLDIVEKIE---NRGDEFVVKTKRKGEFK--------- 113 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRLV--PGT-SLSANVVTYEEQILSRELPKSII- 175 D+ I+ G R + PG + ++Y + ++ Sbjct: 114 ---------------ADSVILGIGVKRRKLGVPGEQEFAGRGISYCSVCDAPLFKNRVVA 158 Query: 176 IAGAGAIGMEFGYVLKNYGVDVTIVEFLP--RALPNEDADVSKEIEKQFKKLGVTILTAT 233 + G G +E +L +Y V ++ +A P V K K V + + Sbjct: 159 VIGGGDSALEGAEILSSYSTKVYLIHRRDTFKAQPIYVETVKK-------KPNVEFVLNS 211 Query: 234 KVESIADG--GSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAI 291 V+ I QV V K G +EL V IGF P + G+ I Sbjct: 212 VVKEIKGDKVVKQVVVENLKTGEIKELNVNGVFIEIGFDPPTDF--AKSNGIETDTNGYI 269 Query: 292 GVDDYMRTNVGHIYAIGDVN----GLLQLAHVAEAQGVVAAETIA 332 VD++MRT+V ++A GD G Q+ A AQG VAA + Sbjct: 270 KVDEWMRTSVPGVFAAGDCTSAWLGFRQVI-TAVAQGAVAATSAY 313 >5UTH-A nrPDB Length = 319 Score = 167 bits (423), Expect = 1e-41, Method: Composition-based stats. Identities = 72/341 (21%), Positives = 123/341 (36%), Gaps = 60/341 (17%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKAL----LRNAE 57 T +DV+++G+GP GY AAI AA+ L + E +GG + + + + E Sbjct: 14 TVHDVIIIGSGPAGYTAAIYAARAQLKPLVFEGTQFGGALMTTTEVENYPGFREGITGPE 73 Query: 58 LVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFAD 117 L+ + A FG M+ ++ G Sbjct: 74 LMDQMREQALRFGA--------------------------DLRMEDVDAVQLEG-----P 102 Query: 118 ANTLLVDLNDGGTESVTFDNAIIATGSSTRLV--PGTS----LSANVVTYEEQILSRELP 171 T++V G E+ I+A G++ R + PG + + + R+ Sbjct: 103 VKTVVV-----GDETHQARAVILAMGAAARHLGVPGEEALTGMGVSTCATCDGFFFRD-- 155 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 + I++ G G ME L + VT++ + +E+ +T LT Sbjct: 156 QDIVVVGGGDSAMEEATFLTRFARSVTLIHRRDEFRAS-----KIMLERARANEKITFLT 210 Query: 232 ATKVESIADGGS--QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRK 289 T++ I V + T G +L V AIG P E L + V L D Sbjct: 211 NTEITQIEGDPKVTGVRLRDTVTGEESKLDVTGVFVAIGHDPRSE---LVRGQVELDDEG 267 Query: 290 AIGV-DDYMRTNVGHIYAIGDVNGL-LQLAHVAEAQGVVAA 328 + V T++ ++A GD+ + A A G A+ Sbjct: 268 YVKVQGRTTYTSLDGVFAAGDLVDHTYRQAITAAGSGCAAS 308 >6BWT-A nrPDB Length = 319 Score = 164 bits (416), Expect = 7e-41, Method: Composition-based stats. Identities = 75/330 (22%), Positives = 118/330 (35%), Gaps = 62/330 (18%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG---VCLNVGCIPSKA-LLRNAEL 58 H+ +++LG+GP GY AAI AA+ L I+ GG +V P + + EL Sbjct: 7 HHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVYNWPGEPDGIMGPEL 66 Query: 59 VHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADA 118 + K A+ FD I YD + V K K+ Sbjct: 67 MEKLQKQAE--------RFDTQIVYD--------TINAVDLQNKPFKLV----------- 99 Query: 119 NTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSL------SANVVTYEEQILSRELPK 172 G E T D IIATG++ + + S + + + K Sbjct: 100 ---------GEVEQYTCDTLIIATGATAKYLGLESEEKFMGKGVSACATCDGFFYKN--K 148 Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTA 232 + + G G +E L N VT++ L +E + K +EK + I+ Sbjct: 149 DVAVVGGGNTAVEEALFLSNIAKSVTLIHRRDT-LRSEKILIDKLMEKAQHGN-INIIWN 206 Query: 233 TKVESIADGGSQV---TVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRK 289 T +E + V + K ++ V AIG PN + AG + Sbjct: 207 TTLEEVLGDDMGVNALRIKNIKTNEESQMGVAGVFIAIGHTPNTSIF----AGQLEMENG 262 Query: 290 AIGV-----DDYMRTNVGHIYAIGDVNGLL 314 I V D +TN+ ++A GDV + Sbjct: 263 YIKVKSGLAGDATQTNIKGVFAAGDVADHV 292 >2A87-A nrPDB Length = 335 Score = 155 bits (392), Expect = 4e-38, Method: Composition-based stats. Identities = 65/338 (19%), Positives = 114/338 (33%), Gaps = 59/338 (17%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG---VCLNVGCIPSKA-LLRNAELVH 60 DV+V+G+GP GY AA+ AA+ L+ + E +GG +V P + EL+ Sbjct: 16 DVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNGITGPELMD 75 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 + A FG ++ + + +G T Sbjct: 76 EMREQALRFGAD----------------------------LRMEDVESVSLHGPLKSVVT 107 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLV--PGTSL----SANVVTYEEQILSRELPKSI 174 ++ I+A G++ R + PG + + R+ + I Sbjct: 108 -------ADGQTHRARAVILAMGAAARYLQVPGEQELLGRGVSSCATCDGFFFRD--QDI 158 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATK 234 + G G ME L + VT+V + +++ + LT Sbjct: 159 AVIGGGDSAMEEATFLTRFARSVTLVHRRDEFRAS-----KIMLDRARNNDKIRFLTNHT 213 Query: 235 VESIADGG--SQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIG 292 V ++ + + V T G L V AIG P GL + + + + Sbjct: 214 VVAVDGDTTVTGLRVRDTNTGAETTLPVTGVFVAIGHEPRS---GLVREAIDVDPDGYVL 270 Query: 293 V-DDYMRTNVGHIYAIGDVNGL-LQLAHVAEAQGVVAA 328 V T++ ++A GD+ + A A G AA Sbjct: 271 VQGRTTSTSLPGVFAAGDLVDRTYRQAVTAAGSGCAAA 308 >5XHU-A nrPDB Length = 329 Score = 153 bits (387), Expect = 2e-37, Method: Composition-based stats. Identities = 75/361 (20%), Positives = 135/361 (37%), Gaps = 66/361 (18%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE--PKYWGGVCL--------NVGCIPSKALL 53 YDV ++G GP G A L T ++E PK G V L ++G IP + Sbjct: 3 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPEKIIRDIGGIPG---I 59 Query: 54 RNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYG 113 +L+ + A TFD I ++ RV G + I G Sbjct: 60 AGKQLIEQLKEQAA--------TFDPDIVLNQ-------RVTGFER-LDDGTIVLTGSEG 103 Query: 114 TFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKS 173 T+++ G E FD+ A + + Y + L K Sbjct: 104 KKHYTRTVILACGMGTLEVNEFDSEDAARYA-----------GKNLHYGVEKLDAFKGKR 152 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 ++I+G G +++ L+ VT+V ++ V+K K+ V +LT Sbjct: 153 VVISGGGDTAVDWANELEPIAASVTVVHRREE-FGGMESSVTK-----MKQSSVRVLTPY 206 Query: 234 KVESI---ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKA 290 ++E + +G VTV T+ G ++++ ++++ GF ++ + + G+ + + Sbjct: 207 RLEQLNGDEEGIKSVTVCHTESGQRKDIEIDELIINHGFK--IDLGPMMEWGLEI-EEGR 263 Query: 291 IGVDDYMRTNVGHIYAIGD----------VNGLLQLAHVAEAQGVVA----AETIAGAET 336 + D +MRTN+ ++ GD + G A AE +A T Sbjct: 264 VKADRHMRTNLPGVFVAGDAAFYESKLRLIAGGFTEGPTAVNSAKAYLDPKAENMAMYST 323 Query: 337 L 337 Sbjct: 324 H 324 >4ZN0-A nrPDB Length = 311 Score = 152 bits (384), Expect = 3e-37, Method: Composition-based stats. Identities = 66/345 (19%), Positives = 115/345 (33%), Gaps = 64/345 (18%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGV---CLNVGCIPSKALLRNAELVH 60 YD++++G GP G A I A + GL T I+E G V P + EL+ Sbjct: 8 YDLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISGQISMADIVENYPGFPSISGLELME 67 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 F A+ G+ +T + + ++K+ Sbjct: 68 RFRTHAQEVGVKTTITEVLSVRSEGTKKI------------------------------- 96 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLV--PGT-SLSANVVTYEEQILSRELPKSII-I 176 + + G + IIATG++ + + PG L + V+Y I+ + Sbjct: 97 --ITTDSGD---LEAKAVIIATGANPKHLGVPGEKELISKGVSYCAICDGPFFRNKIVAV 151 Query: 177 AGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFK-KLGVTILTATKV 235 G G + L V +V ++ ++ + + ++ + V Sbjct: 152 VGGGNSAVTDALFLSKVAQKVYLVHRRDHL------KAARVLQDRVDGTPNIELILNSHV 205 Query: 236 ESIA------DGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRK 289 I ++ + +EL V +G PN E ++K + Sbjct: 206 LEIVGTREGIKKVEKIILEDVNSRETRELSTNGVFIYVGIHPNTEFVDVEK-----DEGG 260 Query: 290 AIGVDDYMRTNVGHIYAIGDVNGLL--QLAHVAEAQGVVAAETIA 332 I D +M T+ IYA GD QL A G +AA Sbjct: 261 FIKTDRWMETSEKGIYAAGDCRDTPIWQLV-TAVRDGAIAATAAY 304 >5U63-A nrPDB Length = 321 Score = 151 bits (381), Expect = 7e-37, Method: Composition-based stats. Identities = 69/328 (21%), Positives = 119/328 (36%), Gaps = 62/328 (18%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPS----KALLRNA 56 + H +++LG+GP GY AAI AA+ L +V GG I + + + Sbjct: 7 IKHAKLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTDEIENWPGDFEMTTGS 66 Query: 57 ELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFA 116 L+ + A+ F E+ FD+ D S + + Sbjct: 67 GLMQRMLQHAEKF--ETEIVFDHINRVDLSSRPFKLF----------------------- 101 Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLV--PGTSLSANVVTY----EEQILSREL 170 G ++ T D IIATG+S R + P + R Sbjct: 102 -----------GDVQNFTCDALIIATGASARYIGLPSEENYKGRGVSACATCDGFFYRNK 150 Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL 230 P + + G G +E L N V ++ + + + K+ ++ + + Sbjct: 151 P--VGVIGGGNTAVEEALYLANIASTVHLIHRRDSF--RAEKILIDRLYKKVEEGKIVLH 206 Query: 231 TATKVESIADGGSQVT---VTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 T ++ + VT + TK G +ELK + + AIG +PN E + + + L Sbjct: 207 TDRTLDEVLGDNMGVTGLRLANTKTGEKEELKLDGLFVAIGHSPNTEIF---QGQLELN- 262 Query: 288 RKAIGVDDYM-----RTNVGHIYAIGDV 310 I V + T+V ++A GDV Sbjct: 263 NGYIVVKSGLDGNATATSVEGVFAAGDV 290 >1F6M-A nrPDB Length = 320 Score = 149 bits (376), Expect = 3e-36, Method: Composition-based stats. Identities = 63/332 (18%), Positives = 110/332 (33%), Gaps = 63/332 (18%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG---VCLNVGCIPSKA-LLRNAE 57 H +++LG+GP GY AA+ AA+ L ++ GG V P L Sbjct: 4 KHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPL 63 Query: 58 LVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFAD 117 L+ + A F E+ FD+ NK+ + Sbjct: 64 LMERMHEHATKF--ETEIIFDHI-----------------------NKVDLQNRPFRL-- 96 Query: 118 ANTLLVDLNDGGTESVTFDNAIIATGSSTRLV--PGTSLSANVVTY----EEQILSRELP 171 +G T D IIATG+S R + P + R Sbjct: 97 ---------NGDNGEYTCDALIIATGASARYLGLPSEEAFKGRGVSASATCDGFFYRN-- 145 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 + + + G G +E L N +V ++ + + K + + + + + T Sbjct: 146 QKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGF--RAEKILIKRLMDKVENGNIILHT 203 Query: 232 ATKVESIADGGSQVTVTVTKDGV----AQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 +E + VT +D + L + AIG +PN + G + Sbjct: 204 NRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFE----GQLELE 259 Query: 288 RKAIGV-----DDYMRTNVGHIYAIGDVNGLL 314 I V + +T++ ++A GDV + Sbjct: 260 NGYIKVQSGIHGNATQTSIPGVFAAGDVMDHI 291 >5USX-A nrPDB Length = 319 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 67/328 (20%), Positives = 116/328 (35%), Gaps = 62/328 (18%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG---VCLNVGCIPS-KALLRNA 56 M H +++LG+GP GY AA+ AA+ L+ ++ GG V P L Sbjct: 4 MKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMQQGGQLTTTTEVENWPGDPEGLTGP 63 Query: 57 ELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFA 116 L+ + A+ F E+ FD+ D S + F++K Sbjct: 64 GLMDRMKEHAERF--ETEIIFDHINEVDFSTRP---------FVLK-------------- 98 Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSL------SANVVTYEEQILSREL 170 G S + D II+TG+S + + S + + R Sbjct: 99 -----------GDAASYSCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGFFYRN- 146 Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL 230 + + + G G +E L N +V ++ + + + + + + + Sbjct: 147 -QKVAVVGGGNTAVEEALYLSNIAAEVHLIHRRDSF--RAEKILINRLMDKVQNGNIVLH 203 Query: 231 TATKVESIADGGSQVTVTVTKD---GVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 T ++ + VT KD G +EL AIG +PN + + G Sbjct: 204 TDRVLDEVLGDEMGVTGVRLKDVKTGGTEELDVMGAFIAIGHSPNTQIFQ----GQLDMK 259 Query: 288 RKAIGVDDYM-----RTNVGHIYAIGDV 310 I V + +T+V I+A GDV Sbjct: 260 DGYILVKSGLEGNATQTSVEGIFAAGDV 287 >1Q1R-A nrPDB Length = 431 Score = 142 bits (358), Expect = 3e-34, Method: Composition-based stats. Identities = 64/266 (24%), Positives = 102/266 (38%), Gaps = 37/266 (13%) Query: 122 LVDLNDGGTESVTFDNAIIATGSSTRLVP---GTSLSANVVTYEEQILSRELPKS----- 173 V L+DG ++ +D ++ATG R +P G AN Y + E + Sbjct: 92 QVILSDG--RALDYDRLVLATGGRPRPLPVASGAVGKANNFRYLRTLEDAECIRRQLIAD 149 Query: 174 --IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNED-ADVSKEIEKQFKKLGVTIL 230 +++ G G IG+E + VT+++ R L VS E ++ GV I Sbjct: 150 NRLVVIGGGYIGLEVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDIR 209 Query: 231 TATKVESIADGGSQ--VTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDR 288 T T+V Q VT + +DG L A+ V+ IG PN E AG+ + Sbjct: 210 TGTQVCGFEMSTDQQKVTAVLCEDGTR--LPADLVIAGIGLIPNCE--LASAAGLQVD-- 263 Query: 289 KAIGVDDYMRTNVGHIYAIGDVNG----------LLQLAHVAEAQGVVAAETIAGAETLT 338 I ++++M+T+ I A+GD ++ A Q A + G Sbjct: 264 NGIVINEHMQTSDPLIMAVGDCARFHSQLYDRWVRIESVPNALEQARKIAAILCGKVPRD 323 Query: 339 LGDHRMLPRATFCQPNVA--SFGLTE 362 P Q + GL+E Sbjct: 324 ----EAAPWFWSDQYEIGLKMVGLSE 345 Score = 38.3 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 42/116 (36%), Gaps = 20/116 (17%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYG--------VDVTIVEFLPRALPNEDADVSKEIE---- 219 +++I G G G+E + L+ G D T++ L E Sbjct: 5 DNVVIVGTGLAGVEVAFGLRASGWEGNIRLVGDATVIPHHLPPLSKAYLAGKATAESLYL 64 Query: 220 ---KQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPN 272 + + +L T+V +I QV + DG A L ++++ A G P Sbjct: 65 RTPDAYAAQNIQLLGGTQVTAINRDRQQV---ILSDGRA--LDYDRLVLATGGRPR 115 Score = 28.3 bits (62), Expect = 7.4, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 14/28 (50%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 +VV+G G G A A + + +++ Sbjct: 152 LVVIGGGYIGLEVAATAIKANMHVTLLD 179 >5W4C-A nrPDB Length = 371 Score = 141 bits (356), Expect = 6e-34, Method: Composition-based stats. Identities = 75/332 (22%), Positives = 115/332 (34%), Gaps = 60/332 (18%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-----YWGG---VCLNVGCIPSKA-L 52 H VV++G+GPGG+ AAI A+ L + E GG +V P Sbjct: 29 MHSKVVIIGSGPGGHTAAIYLARANLEPVLYEGMLANGFAPGGQLTTTTDVENFPGFPEG 88 Query: 53 LRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGY 112 + E++ F ++ FG K+ VA V ++ K Sbjct: 89 VTGTEMMDKFRAQSERFG----------------TKIITETVARVDLSVRPFK------- 125 Query: 113 GTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLV--PGTSLSANVVTYEEQILSREL 170 + + E +T D I+ATG+S + + PG + + Sbjct: 126 --------YWTEGEEEEHEFMTADTIILATGASAKRLFLPGEETYWQSGISACAVCDGAV 177 Query: 171 P----KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKL- 225 P K + + G G E L YG V ++ SK + K+ Sbjct: 178 PIFRQKPLAVIGGGDSAAEEATYLTKYGSHVYVLVRRDEL------RASKIMAKRLTSHP 231 Query: 226 GVTILTATKVESIADGGS---QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAG 282 VT+L T G +T+ TK G +L + AIG P L K+ Sbjct: 232 KVTVLWNTVATEAKGDGEVLTSLTIKNTKTGETGDLPVNGLFYAIGHEPAT---SLVKSQ 288 Query: 283 VALTDRKAIG-VDDYMRTNVGHIYAIGDVNGL 313 V L I V +T+V ++A GDV Sbjct: 289 VELDSDGYIKTVPGTSQTSVHGVFAAGDVQDK 320 >3LXD-A nrPDB Length = 415 Score = 139 bits (350), Expect = 3e-33, Method: Composition-based stats. Identities = 64/247 (25%), Positives = 102/247 (41%), Gaps = 28/247 (11%) Query: 116 ADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV----TYEEQ----ILS 167 D V L DG ++ + I ATG R + V T E+ Sbjct: 91 LDPAAHTVKLGDGS--AIEYGKLIWATGGDPRRLSCVGADLAGVHAVRTKEDADRLMAEL 148 Query: 168 RELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDAD-VSKEIEKQFKKLG 226 K+ ++ G G IG+E VL +GV+VT++E LPR L + +S+ + + + G Sbjct: 149 DAGAKNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVAGEALSEFYQAEHRAHG 208 Query: 227 VTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALT 286 V + T ++ I G++VT +DG + A+ V+ IG P V A + Sbjct: 209 VDLRTGAAMDCIEGDGTKVTGVRMQDGSV--IPADIVIVGIGIVPCVGALISAGA----S 262 Query: 287 DRKAIGVDDYMRTNVGHIYAIGDVNGL---------LQLAHV--AEAQGVVAAETIAGAE 335 + VD++ RT++ +YAIGD ++L V A AA+ I GA Sbjct: 263 GGNGVDVDEFCRTSLTDVYAIGDCAAHANDFADGAVIRLESVQNANDMATAAAKDICGAP 322 Query: 336 TLTLGDH 342 Sbjct: 323 VPYKATP 329 Score = 28.7 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 15/28 (53%) Query: 7 VVLGAGPGGYVAAIRAAQLGLSTAIVEP 34 VV+G G G AA + G++ ++E Sbjct: 156 VVIGGGYIGLEAAAVLTKFGVNVTLLEA 183 >3FG2-P nrPDB Length = 404 Score = 137 bits (346), Expect = 9e-33, Method: Composition-based stats. Identities = 59/261 (22%), Positives = 97/261 (37%), Gaps = 26/261 (9%) Query: 98 HFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSAN 157 + I I D + L G ++ + + ++ATG+ R++ + S Sbjct: 64 EKFFQDQAIELISDRMVSIDREGRKLLLASGT--AIEYGHLVLATGARNRMLDVPNASLP 121 Query: 158 VVTYEEQILSREL-------PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNE 210 V Y + E+ K +++ GAG IG+EF + G++V +VE PR + Sbjct: 122 DVLYLRTLDESEVLRQRMPDKKHVVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMARV 181 Query: 211 D-ADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGF 269 ++S + G+ + + IA G +VT V DG L + V+ +G Sbjct: 182 VTPEISSYFHDRHSGAGIRMHYGVRATEIAAEGDRVTGVVLSDGN--TLPCDLVVVGVGV 239 Query: 270 APNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDV----------NGLLQLAHV 319 PNVE I VD + T+ HI AIGD ++ Sbjct: 240 IPNVEIAAAAGL----PTAAGIIVDQQLLTSDPHISAIGDCALFESVRFGETMRVESVQN 295 Query: 320 AEAQGVVAAETIAGAETLTLG 340 A Q A + G G Sbjct: 296 ATDQARCVAARLTGDAKPYDG 316 Score = 29.1 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 13/28 (46%), Positives = 15/28 (53%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 VVV+GAG G A A GL +VE Sbjct: 145 VVVIGAGFIGLEFAATARAKGLEVDVVE 172 >5JCN-A nrPDB Length = 451 Score = 136 bits (343), Expect = 2e-32, Method: Composition-based stats. Identities = 65/250 (26%), Positives = 98/250 (39%), Gaps = 35/250 (14%) Query: 124 DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELP------------ 171 L + T++ IIATGSS + + + RE+ Sbjct: 121 TLTSAVGATFTYEILIIATGSSVIKL--SDFGTQGADSNNILYLREVDDADKLVAAIQAK 178 Query: 172 --KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVSKEIEKQFKKLGVT 228 +I G G IG+E LK DVT+V P +P AD++ E + GV Sbjct: 179 KGGKAVIVGGGYIGLELSAALKINDFDVTMVFPEPWCMPRLFTADIAAFYESYYTNKGVK 238 Query: 229 ILTATKVESI-ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 I+ T AD VT K+G L+A+ V+ +G P L K VA + Sbjct: 239 IVKGTVAVGFDADANGDVTAVNLKNGSV--LEADIVVVGVGGRPLTT---LFKGQVA-EE 292 Query: 288 RKAIGVDDYMRTNVGHIYAIGDVNGLLQ--------LAHV--AEAQGVVAAETIAGAET- 336 + I D + T+V +YA+GDV + HV A A + I G E+ Sbjct: 293 KGGIKTDAFFETSVPGVYAVGDVATFPMKMYNELRRVEHVDHARKSAEQAVKAIKGKESG 352 Query: 337 LTLGDHRMLP 346 ++ ++ LP Sbjct: 353 ESVVEYDYLP 362 Score = 30.3 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 29/173 (16%), Positives = 47/173 (27%), Gaps = 32/173 (18%) Query: 16 YVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGEV 75 VAAI+A + G IV Y G L A ++ F +V Sbjct: 171 LVAAIQA-KKGGKAVIVGGGYIG------------LELSAALKINDF-----------DV 206 Query: 76 TFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTF---ADANTLLVDLNDGGTES 132 T + + R A + + G ADAN + +N Sbjct: 207 TMVFPEPWCMPRLFTADIAAFYESYYTNKGVKIVKGTVAVGFDADANGDVTAVNLKNGSV 266 Query: 133 VTFDNAIIATGSST--RLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIG 183 + D ++ G L G + +P + G + Sbjct: 267 LEADIVVVGVGGRPLTTLFKGQVAEEKGGIKTDAFFETSVPGVYAV---GDVA 316 >2V3B-A nrPDB Length = 384 Score = 133 bits (336), Expect = 1e-31, Method: Composition-based stats. Identities = 86/425 (20%), Positives = 152/425 (35%), Gaps = 72/425 (16%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKD 65 +V++G G GY A +L T L+ A+ ++K Sbjct: 7 LVIIGTGLAGYNLAREWRKLDGET--------------------PLLMITADDGRSYSKP 46 Query: 66 AKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDL 125 + G S D G+A +AE A + H T D + + Sbjct: 47 MLSTGFSKNKDAD-GLAMAEPGAMAEQLNARI----------LTHTRVTGIDPGHQRIWI 95 Query: 126 NDGGTESVTFDNAIIATGSSTRLVPGTSLSAN----VVTYEEQILSREL---PKSIIIAG 178 G E V + + ++A G+ VP + + + E+ R+ + +++ G Sbjct: 96 ---GEEEVRYRDLVLAWGAEPIRVPVEGDAQDALYPINDLEDYARFRQAAAGKRRVLLLG 152 Query: 179 AGAIGMEFGYVLKNYGVDVTIVEFLPRALPN-EDADVSKEIEKQFKKLGVTILTATKVES 237 AG IG EF L + G + +V + +P +K ++ + LGV + S Sbjct: 153 AGLIGCEFANDLSSGGYQLDVVAPCEQVMPGLLHPAAAKAVQAGLEGLGVRFHLGPVLAS 212 Query: 238 IADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYM 297 + G + ++ + + + V+ A+G P E AG+A+ + I VD + Sbjct: 213 LKKAGEGLEAHLSD---GEVIPCDLVVSAVGLRPRTE--LAFAAGLAVN--RGIVVDRSL 265 Query: 298 RTNVGHIYAIGDV--NGLLQLAHVA--EAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 RT+ +IYA+GD L L +V A A+T+AG + + +P Sbjct: 266 RTSHANIYALGDCAEVDGLNLLYVMPLMACARALAQTLAGNPSQVA--YGPMPVTVKTP- 322 Query: 354 NVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVG 413 + L V P V +K++ G ++G L G Sbjct: 323 ---ACPL-------------VVSPPPRGMDGQWLVEGSGTDLKVLCRDTAGRVIGYALTG 366 Query: 414 HDVAE 418 V E Sbjct: 367 AAVNE 371 >4CBQ-A nrPDB Length = 314 Score = 131 bits (331), Expect = 5e-31, Method: Composition-based stats. Identities = 66/344 (19%), Positives = 117/344 (34%), Gaps = 63/344 (18%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG--------VCLNVGCIPSKA-LLR 54 +DVV++G+GP + AAI + L + E GG + P + Sbjct: 5 HDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGVAAGGQLTTTTIIENFPGFPNGID 64 Query: 55 NAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGT 114 EL+ ++ +G + + V F + K+ G Sbjct: 65 GNELMMNMRTQSEKYG----------------TTIITETIDHVDFSTQPFKLFTEEG--- 105 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATGSSTR--LVPGTSLSANVVTYEEQILSRELP- 171 + V + IIATG++ + VPG I +P Sbjct: 106 ----------------KEVLTKSVIIATGATAKRMHVPGEDKYWQNGVSACAICDGAVPI 149 Query: 172 ---KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVT 228 K +++ G G ME L YG V I+ ++ E+ + Sbjct: 150 FRNKVLMVVGGGDAAMEEALHLTKYGSKVIILHRRDAFRASKTMQ-----ERVLNHPKIE 204 Query: 229 ILTATKVESIADGGS---QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVAL 285 ++ +++ + G + G + + + AIG +PN + G V Sbjct: 205 VIWNSELVELEGDGDLLNGAKIHNLVSGEYKVVPVAGLFYAIGHSPNSKFLG---GQVKT 261 Query: 286 TDRKAIGVDDYMRTNVGHIYAIGDVNGLL-QLAHVAEAQGVVAA 328 D I + +T+V ++A GDV + + A VA G +AA Sbjct: 262 ADDGYILT-EGPKTSVDGVFACGDVCDRVYRQAIVAAGSGCMAA 304 >6BPY-A nrPDB Length = 374 Score = 129 bits (325), Expect = 2e-30, Method: Composition-based stats. Identities = 65/336 (19%), Positives = 107/336 (31%), Gaps = 59/336 (17%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-----KYWGG---VCLNVGCIPSKA- 51 M H VV++G+GP + AAI ++ L + E GG ++ P Sbjct: 2 MVHTKVVIIGSGPAAHTAAIYLSRAELKPVLYEGMLANGTAAGGQLTTTTDIENFPGFPD 61 Query: 52 LLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHG 111 + AEL+ K + FG EV + D S K + Sbjct: 62 GIGGAELMENMRKQSIRFG--TEVITETISRVDLSSKPFKLWT----------------- 102 Query: 112 YGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLV--PGTSLSANVVTYEEQILSRE 169 + + T D IIATG++ R + PG + Sbjct: 103 ----------EWNDGPDKEPACTADAVIIATGANARRLNLPGEETYWQNGISACAVCDGA 152 Query: 170 LP----KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKL 225 +P K + + G G E L YG VT++ + ++K + Sbjct: 153 VPIFRNKPLYVIGGGDSAAEEAMFLAKYGSSVTVLVRRDKL--RASKAMAKRL---LAHP 207 Query: 226 GVTILTATKVESIADGGS------QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLD 279 VT+ T + + + T G + + A + A+G P L Sbjct: 208 KVTVRFNTVATEVLGEKKPNGLMTHLRIKNTVTGEEEIVDANGLFYAVGHDPAT---ALV 264 Query: 280 KAGVALTDRKAIGVDD-YMRTNVGHIYAIGDVNGLL 314 K + L + I T+ ++A GDV Sbjct: 265 KGQIDLDEDGYIITKPGTSYTSREGVFACGDVQDKR 300 >3KLJ-A nrPDB Length = 385 Score = 128 bits (321), Expect = 7e-30, Method: Composition-based stats. Identities = 71/341 (20%), Positives = 132/341 (38%), Gaps = 66/341 (19%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKD 65 +++LGAGP G+ AA A LG C ++ ++ + + + Sbjct: 12 ILILGAGPAGFSAAK--AALGK-------------CDDI------TMINSEKYL------ 44 Query: 66 AKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDL 125 +++ + + + + K N + T D N LV L Sbjct: 45 -------PYYRPRLNEIIAKNKSIDDILIKKNDWYEKNNIKVITSEFATSIDPNNKLVTL 97 Query: 126 NDGGTESVTFDNAIIATGS--STRLVPGTSLSANVVTYEEQILSRELPK---SIIIAGAG 180 G E + ++ IIA+GS + VP ++ +Y++ + ++ K I G G Sbjct: 98 KSG--EKIKYEKLIIASGSIANKIKVPHADEIFSLYSYDDALKIKDECKNKGKAFIIGGG 155 Query: 181 AIGMEFGYVLKNYGVDVTIVEFLPRAL-PNEDADVSKEIEKQFKKLGVTILTATKVESIA 239 +G+E + + G +I L L D D ++ + +LG+ I T + E + Sbjct: 156 ILGIELAQAIIDSGTPASIGIILEYPLERQLDRDGGLFLKDKLDRLGIKIYTNSNFEEMG 215 Query: 240 DGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRT 299 D +++ V+ A+G PN++ + ++ I V+D+M T Sbjct: 216 D----------------LIRSSCVITAVGVKPNLDFI----KDTEIASKRGILVNDHMET 255 Query: 300 NVGHIYAIGDVNGL----LQLAHVAEAQGVVAAETIAGAET 336 ++ IYA GDV L ++A QG VA G + Sbjct: 256 SIKDIYACGDVAEFYGKNPGLINIANKQGEVAGLNACGEDA 296 >2YVG-A nrPDB Length = 408 Score = 127 bits (319), Expect = 1e-29, Method: Composition-based stats. Identities = 60/245 (24%), Positives = 100/245 (40%), Gaps = 31/245 (12%) Query: 113 GTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVP---GTSLSANVV-TYEEQILSR 168 D V L+DG ++ + ++ATG++ R +P G ++ + + T E+ + Sbjct: 82 AQSFDPQAHTVALSDG--RTLPYGTLVLATGAAPRALPTLQGATMPVHTLRTLEDARRIQ 139 Query: 169 E--LPK-SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRAL-PNEDADVSKEIEKQFKK 224 P+ ++I G G IG+E + GV V++VE PR + A ++ + + Sbjct: 140 AGLRPQSRLLIVGGGVIGLELAATARTAGVHVSLVETQPRLMSRAAPATLADFVARYHAA 199 Query: 225 LGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVA 284 GV + V DG V + DG + A+ V+ IG N AG+A Sbjct: 200 QGVDLRFERSVTGSVDG-----VVLLDDGTR--IAADMVVVGIGVLAN--DALARAAGLA 250 Query: 285 LTDRKAIGVDDYMRTNVGHIYAIGDVNG----------LLQLAHVAEAQGVVAAETIAGA 334 D I VD Y RT +YA+GDV ++ A+ QG+ A + Sbjct: 251 CDD--GIFVDAYGRTTCPDVYALGDVTRQRNPLSGRFERIETWSNAQNQGIAVARHLVDP 308 Query: 335 ETLTL 339 Sbjct: 309 TAPGY 313 >3D8X-A nrPDB Length = 326 Score = 124 bits (312), Expect = 8e-29, Method: Composition-based stats. Identities = 67/343 (19%), Positives = 106/343 (30%), Gaps = 60/343 (17%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG--------VCLNVGCIPSKA-LLRNA 56 V ++G+GP + AAI A+ + + E G + P L + Sbjct: 13 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 72 Query: 57 ELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFA 116 EL+ + + FG + V+ V K K Sbjct: 73 ELMDRMREQSTKFGTE----------------IITETVSKVDLSSKPFK----------- 105 Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTR--LVPGTSLSANVVTYEEQILSRELP--- 171 L + E VT D I+ATG+S + +PG + +P Sbjct: 106 -----LWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFR 160 Query: 172 -KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL 230 K + + G G E L YG V ++ + E K + IL Sbjct: 161 NKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAE-----KNEKIEIL 215 Query: 231 TATKVESIADGGS---QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 T G + + TK +L + AIG P + + V + Sbjct: 216 YNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK---IVAGQVDTDE 272 Query: 288 RKAIG-VDDYMRTNVGHIYAIGDVNG-LLQLAHVAEAQGVVAA 328 I V T+V +A GDV + A + G +AA Sbjct: 273 AGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 315 >2ZBW-A nrPDB Length = 335 Score = 121 bits (303), Expect = 9e-28, Method: Composition-based stats. Identities = 67/321 (20%), Positives = 114/321 (35%), Gaps = 42/321 (13%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHI 61 H DV+++GAGP G A GLS V+P GG + P K + A + Sbjct: 5 HTDVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPEPGGQLTALY--PEKYIYDVAGFPKV 62 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTL 121 + KD + F+ + R + K+T G Sbjct: 63 YAKDLVKGLVEQVAPFNPVYSLGE-------RAETLEREGDLFKVTTSQGNA-------- 107 Query: 122 LVDLNDGGTESVTFDNAIIATGS---STRLV--PGT-SLSANVVTYEEQILSRELPKSII 175 T IIA G R + PG V Y + + K ++ Sbjct: 108 -----------YTAKAVIIAAGVGAFEPRRIGAPGEREFEGRGVYYAVKSKAEFQGKRVL 156 Query: 176 IAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKV 235 I G G +++ L + +T++ P+ KE+ K ++ + +LT ++ Sbjct: 157 IVGGGDSAVDWALNLLDTARRITLIHRRPQF--RAHEASVKELMKAHEEGRLEVLTPYEL 214 Query: 236 ESIADGGSQVTVTVTKDGVAQEL--KAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV 293 + V + +EL + + VL G+ + L G+AL ++ I V Sbjct: 215 RRVEGDERVRWAVVFHNQTQEELALEVDAVLILAGYI--TKLGPLANWGLAL-EKNKIKV 271 Query: 294 DDYMRTNVGHIYAIGDVNGLL 314 D M T++ +YA GD+ Sbjct: 272 DTTMATSIPGVYACGDIVTYP 292 >3ISH-A nrPDB Length = 311 Score = 120 bits (302), Expect = 1e-27, Method: Composition-based stats. Identities = 67/343 (19%), Positives = 119/343 (34%), Gaps = 63/343 (18%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIV-EPKYWGGVCLNVGCIPS----KALLRNAELV 59 D ++G GP G A + A + G+ A++ E GG I + K ++ + + Sbjct: 3 DCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLDFM 62 Query: 60 HIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADAN 119 + + FG+ E+T V + KK D++ Sbjct: 63 QPWQEQCFRFGLKHEMT-------------------AVQRVSKK-------------DSH 90 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSL----SANVVTYEEQILSRELPKS 173 +++ + ++ + IIATG S + + G S + + + K Sbjct: 91 FVILAEDG---KTFEAKSVIIATGGSPKRTGIKGESEYWGKGVSTCATCDGFFYKN--KE 145 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP--RALPNEDADVSKEIEKQFKKLGVTILT 231 + + G G +E L N V ++ R P +E + LT Sbjct: 146 VAVLGGGDTAVEEAIYLANICKKVYLIHRRDGFRCAPI-------TLEHAKNNDKIEFLT 198 Query: 232 ATKVESIADGGSQV---TVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGV--ALT 286 VE I S V ++ T +EL +G+ N + + Sbjct: 199 PYVVEEIKGDASGVSSLSIKNTATNEKRELVVPGFFIFVGYDVNNAVLKQEDNSMLCKCD 258 Query: 287 DRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHV-AEAQGVVAA 328 + +I VD M+TNV ++A GD+ V A + G AA Sbjct: 259 EYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATAA 301 >3R9U-A nrPDB Length = 315 Score = 116 bits (291), Expect = 2e-26, Method: Composition-based stats. Identities = 62/340 (18%), Positives = 115/340 (33%), Gaps = 57/340 (16%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLS-TAIVEPKYWGGVCLNVGCIPSKA----LLRNAELV 59 DV ++G GP G A + A + GL + E GG + I + ++ + Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSEIENYPGVAQVMDGISFM 65 Query: 60 HIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADAN 119 +++ FG+ E+ GV ++K + G+F Sbjct: 66 APWSEQCMRFGLKHEMV-------------------GVEQILK-------NSDGSF---- 95 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSA------NVVTYEEQILSRELPKS 173 + L G TE I+ TGS+ + + + + K Sbjct: 96 --TIKLEGGKTEL--AKAVIVCTGSAPKKAGFKGEDEFFGKGVSTCATCDGFFYKN--KE 149 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + + G G +E L N + ++ +EK K + ++T+ Sbjct: 150 VAVLGGGDTALEEALYLANICSKIYLIHRRDEF-----RAAPSTVEKVKKNEKIELITSA 204 Query: 234 KVESIADGGSQV--TVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGV--ALTDRK 289 V+ + V KDG ++L + +G E D + + + Sbjct: 205 SVDEVYGDKMGVAGVKVKLKDGSIRDLNVPGIFTFVGLNVRNEILKQDDSKFLCNMEEGG 264 Query: 290 AIGVDDYMRTNVGHIYAIGDVN-GLLQLAHVAEAQGVVAA 328 + VD M+T+V ++A GD+ + A G VAA Sbjct: 265 QVSVDLKMQTSVAGLFAAGDLRKDAPKQVICAAGDGAVAA 304 >4JNQ-A nrPDB Length = 345 Score = 115 bits (289), Expect = 3e-26, Method: Composition-based stats. Identities = 66/344 (19%), Positives = 116/344 (33%), Gaps = 66/344 (19%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCL---NVGCIPSKAL-LRNAELVHI 61 V+V+G+GP GY AAI AA+ L ++ GG + +V P A ++ ++ Sbjct: 29 VIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQGGQLMITTDVENYPGYAEPVQGPWMMEQ 88 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTL 121 + A+ G ++ + V ++ + Sbjct: 89 MARQAENVGA----------------QIVHDIITEVETTVRPFR---------------- 116 Query: 122 LVDLNDGGTESVTFDNAIIATGSSTRLVP------GTSLSANVVTYEEQILSRELPKSII 175 L T D IIATG+ + + + + R K ++ Sbjct: 117 ---LKGDSGTIYTCDALIIATGAQAKWLGLESEQTFMGGGVSACATCDGFFYR--GKDVV 171 Query: 176 IAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKV 235 + G G +E L + VTIV + + + + V+++ + + Sbjct: 172 VVGGGNTAVEEALYLSHIAKSVTIVHRRDGF--RAEKIMQDRL---LSRENVSVVWNSVI 226 Query: 236 ESI---------ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALT 286 + I + V + G QE V AIG AP V L + + Sbjct: 227 DEILGTEARPPMGATVTGVRLKNIVTGETQERATHGVFIAIGHAPAV---SLFEGKLKQK 283 Query: 287 DRKAIGVD-DYMRTNVGHIYAIGDVN-GLLQLAHVAEAQGVVAA 328 + D T+V I+A GDV + + A A G +AA Sbjct: 284 PNGYLWTAPDSTATDVPGIFAAGDVTDDIYRQAVTAAGMGCMAA 327 >3AB1-A nrPDB Length = 360 Score = 115 bits (289), Expect = 4e-26, Method: Composition-based stats. Identities = 60/320 (18%), Positives = 111/320 (34%), Gaps = 42/320 (13%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIFT 63 D+ ++G GP G AA + +S I+E GG + P K + A + Sbjct: 16 DLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQLAALY--PEKHIYDVAGFPEVPA 73 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV 123 D + ++ + + + G Sbjct: 74 IDLVESLWAQAERYNPDVVLNETVTKYTKLDDG-------------------------TF 108 Query: 124 DLNDGGTESVTFDNAIIATGS---STRLVP----GTSLSANVVTYEEQILSRELPKSIII 176 + +IA G R +P L+ + V Y + + K ++I Sbjct: 109 ETRTNTGNVYRSRAVLIAAGLGAFEPRKLPQLGNIDHLTGSSVYYAVKSVEDFKGKRVVI 168 Query: 177 AGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVE 236 G G +++ L VT+V + E+E+ + + T+V Sbjct: 169 VGGGDSALDWTVGLIKNAASVTLVHRGHEF--QGHGKTAHEVERARANGTIDVYLETEVA 226 Query: 237 SIADGGSQVTVTVT--KDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVD 294 SI + +T DG ++A+++L IGF N+ L + + L + A+ VD Sbjct: 227 SIEESNGVLTRVHLRSSDGSKWTVEADRLLILIGFKSNLGP--LARWDLELYE-NALVVD 283 Query: 295 DYMRTNVGHIYAIGDVNGLL 314 +M+T+V +YA GD+ Sbjct: 284 SHMKTSVDGLYAAGDIAYYP 303 >5M5J-A nrPDB Length = 325 Score = 115 bits (287), Expect = 6e-26, Method: Composition-based stats. Identities = 66/329 (20%), Positives = 110/329 (33%), Gaps = 54/329 (16%) Query: 13 PGGYVAAIRAAQLGLSTAI---VEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAF 69 P G A I A++ L T + +E +V PS ++ L+ A+ Sbjct: 27 PAGLTAGIYASRANLKTCVFVGIEHTSQMFTTTDVENFPSHTAIKGPALMEAIQNQAEHC 86 Query: 70 GISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGG 129 G + I +HGY Sbjct: 87 GAELLYEDVHSIDV------------------SSRPFKIVHGY----------------E 112 Query: 130 TESVTFDNAIIATGSSTRLVPGTSLSAN---VVTYEEQILSR-ELPKSIIIAGAGAIGME 185 E+ D IIATG++ R + V+ S K +++ G G + E Sbjct: 113 NETTLADALIIATGATARRLDCKGEKEYWQKGVSACAVCDSAMATGKEVVVVGGGDVACE 172 Query: 186 FGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQV 245 L V +V + + + ++K + + I+ + ++ I G V Sbjct: 173 EATYLTKIATKVYMVLRRDKFRAS-----AAMVKKVMNEKLIEIIYDSAIDEIKGDGKCV 227 Query: 246 T---VTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY--MRTN 300 T + KDG + L A + A+G P L K + + I + D+ RT+ Sbjct: 228 TSVSIKNLKDGKTRTLNAGALYWAVGHDPQTSF--LKKGQLEQDEAGYILLKDHPTQRTS 285 Query: 301 VGHIYAIGDVNG-LLQLAHVAEAQGVVAA 328 V ++A GD L + A VA G AA Sbjct: 286 VDGVFAAGDCCDHLYRQAVVAAGSGSKAA 314 >4EMJ-A nrPDB Length = 410 Score = 114 bits (285), Expect = 1e-25, Method: Composition-based stats. Identities = 55/207 (26%), Positives = 87/207 (42%), Gaps = 17/207 (8%) Query: 116 ADANTLLVDLNDGGTESVTFDNAIIATGSSTR--LVPGTSLSANVV--TYEEQILSRELP 171 D T + L+DG T ++ D +IATGS R +PG+ L V TY + + R+ Sbjct: 83 LDVQTRTISLDDGTT--LSADAIVIATGSRARTMALPGSQLPGVVTLRTYGDVQVLRDSW 140 Query: 172 K---SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNED-ADVSKEIEKQFKKLGV 227 ++I G G IG E + G+ VTI+E L + + +LGV Sbjct: 141 TSATRLLIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRVLGRRIGAWLRGLLTELGV 200 Query: 228 TILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 + T V + G Q+ + DG + A+ L +G P +AG+A Sbjct: 201 QVELGTGVVGFS-GEGQLEQVMASDG--RSFVADSALICVGAEP--ADQLARQAGLACD- 254 Query: 288 RKAIGVDDYMRTNVGHIYAIGDVNGLL 314 + + VD T ++A+GDV Sbjct: 255 -RGVIVDHCGATLAKGVFAVGDVASWP 280 Score = 30.6 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 37/118 (31%), Gaps = 19/118 (16%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA-LPNEDADVSKEIEKQ---------- 221 + I G G G L+ G + I LP + +SK + Sbjct: 4 HVAIIGNGVGGFTTAQALRAEGFEGRISLIGDEPHLPYDRPSLSKAVLDGSLERPPILAE 63 Query: 222 ---FKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGY 276 + + + +LT +V ++ Q DG L A+ ++ A G Sbjct: 64 ADWYGEARIDMLTGPEVTAL---DVQTRTISLDDGT--TLSADAIVIATGSRARTMAL 116 Score = 28.3 bits (62), Expect = 8.0, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 17/30 (56%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPK 35 ++++G G G A A +LGLS I+E Sbjct: 146 LLIVGGGLIGCEVATTARKLGLSVTILEAG 175 >1VDC-A nrPDB Length = 333 Score = 113 bits (282), Expect = 2e-25, Method: Composition-based stats. Identities = 69/349 (19%), Positives = 113/349 (32%), Gaps = 70/349 (20%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP-----KYWGG---VCLNVGCIPSKA-LLRNA 56 + ++G+GP + AAI AA+ L + E GG +V P + Sbjct: 11 LCIVGSGPAAHTAAIYAARAELKPLLFEGWMANDIAPGGQLTTTTDVENFPGFPEGILGV 70 Query: 57 ELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFA 116 EL F K ++ FG + V V F K K+ F Sbjct: 71 ELTDKFRKQSERFG----------------TTIFTETVTKVDFSSKPFKL--------FT 106 Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTY----------EEQIL 166 D+ +L D I+A G+ + + + + + Sbjct: 107 DSKAIL------------ADAVILAIGAVAKRLSFVGSGEVLGGFWNRGISACAVCDGAA 154 Query: 167 SRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLG 226 K + + G G ME L YG V I+ ++ ++ Sbjct: 155 PIFRNKPLAVIGGGDSAMEEANFLTKYGSKVYIIHRRDAFRASKIMQ-----QRALSNPK 209 Query: 227 VTILTA-TKVESIADGGSQV----TVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKA 281 + ++ + VE+ DG V V G +LK + AIG P + Sbjct: 210 IDVIWNSSVVEAYGDGERDVLGGLKVKNVVTGDVSDLKVSGLFFAIGHEPATKFL---DG 266 Query: 282 GVALTDRKAIGVDD-YMRTNVGHIYAIGDVNG-LLQLAHVAEAQGVVAA 328 GV L + +T+V ++A GDV + A A G +AA Sbjct: 267 GVELDSDGYVVTKPGTTQTSVPGVFAAGDVQDKKYRQAITAAGTGCMAA 315 >5JFC-L nrPDB Length = 474 Score = 112 bits (281), Expect = 3e-25, Method: Composition-based stats. Identities = 64/363 (17%), Positives = 119/363 (32%), Gaps = 88/363 (24%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIFTK 64 V ++GAGP G A A++G I E GG + + IP L E+V + Sbjct: 157 VAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGG--VLIYGIPEFRL--PKEIVKKELE 212 Query: 65 DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVD 124 + + G+ E + ++ E R Sbjct: 213 NLRRLGVKIE----TNVLVGKTITFEELRE------------------------------ 238 Query: 125 LNDGGTESVTFDNAIIATGS-STRLVPGTSLSANVVTYEEQILSR--------------- 168 +D I TG+ + R+ P ++ N + + L+R Sbjct: 239 ---------EYDAIFIGTGAGTPRIYPWPGVNLNGIYSANEFLTRINLMKAYKFPEYDTP 289 Query: 169 -ELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGV 227 ++ K + + G G M+ G +V I+ R ++ +E K ++ GV Sbjct: 290 IKVGKRVAVIGGGNTAMDAARSALRLGAEVWILYRRTR----KEMTAREEEIKHAEEEGV 345 Query: 228 TILTATKVESIADGGSQ----VTVTVTKDGVAQE--------------LKAEKVLQAIGF 269 + + + + + K G E ++ + + AIG Sbjct: 346 KFMFLVTPKRFIGDENGNLKAIELEKMKLGEPDESGRRRPIPTGETFIMEFDTAIIAIGQ 405 Query: 270 APNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAE 329 PN G+ + + I VD+ + T++ ++A GD +A G AA+ Sbjct: 406 TPNKTFLETVP-GLKVDEWGRIVVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAK 464 Query: 330 TIA 332 I Sbjct: 465 AIH 467 Score = 49.5 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 43/122 (35%), Gaps = 21/122 (17%) Query: 156 ANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALP------- 208 + + EE + K + I GAG G+ L G +VTI E L + Sbjct: 139 DDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLIYGIP 198 Query: 209 --NEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQA 266 ++ K+ + ++LGV I T V G +T + + + + Sbjct: 199 EFRLPKEIVKKELENLRRLGVKIETNVLV------GKTITFEELR------EEYDAIFIG 246 Query: 267 IG 268 G Sbjct: 247 TG 248 >5KVH-A nrPDB Length = 543 Score = 111 bits (278), Expect = 6e-25, Method: Composition-based stats. Identities = 76/357 (21%), Positives = 134/357 (37%), Gaps = 66/357 (18%) Query: 19 AIRAAQLGLSTAIV-EPKYWGGVCLNVGCIP------SKALLRNAE-LVHIFTKDAKAFG 70 +IRA G IV E P SK L + + V + +A G Sbjct: 73 SIRARDPGARVLIVSEDPEL----------PYMRPPLSKELWFSDDPNVTKTLRFKQANG 122 Query: 71 ISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGT 130 + F Y ++ + GV L K + D +V LNDG Sbjct: 123 KERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQ--------LDVRDNMVKLNDGS- 173 Query: 131 ESVTFDNAIIATGSSTRLVP-----GTSLSANVVTYEEQILSREL------PKSIIIAGA 179 +T++ +IATG + R + G + + + + R L KSI I G Sbjct: 174 -QITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGG 232 Query: 180 GAIGMEFGYVL----KNYGVDVTIVEF----LPRALPNEDADVSKEIEKQFKKLGVTILT 231 G +G E L + G +V + + + LP +S ++ ++ GV ++ Sbjct: 233 GFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEY---LSNWTMEKVRREGVKVMP 289 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALT-DRKA 290 V+S+ ++ + KDG ++++ + ++ A+G PNVE G+ + D Sbjct: 290 NAIVQSVGVSSGKLLIK-LKDG--RKVETDHIVAAVGLEPNVE--LAKTGGLEIDSDFGG 344 Query: 291 IGVDDYMRTNVGHIYAIGDVN-------GLLQLAH--VAEAQGVVAAETIAGAETLT 338 V+ ++ +I+ GD G ++ H A G +A E + GA Sbjct: 345 FRVNAELQAR-SNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPY 400 >1XHC-A nrPDB Length = 367 Score = 109 bits (272), Expect = 3e-24, Method: Composition-based stats. Identities = 81/394 (20%), Positives = 143/394 (36%), Gaps = 71/394 (18%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIP--SKALLRNAELVHIFT 63 VV++G GPGG+ A + +Q +++ + +P SK +L + + F Sbjct: 11 VVIVGNGPGGFELAKQLSQT-YEVTVIDKEP----------VPYYSKPML--SHYIAGFI 57 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV 123 + F + D+ R G+ + + D +V Sbjct: 58 PRNRLF----PYSLDW------------YRKRGIEIRLAE--------EAKLIDRGRKVV 93 Query: 124 DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAI- 182 G V +D ++ATG+ R P ++T + + +SI +G I Sbjct: 94 ITEKGE---VPYDTLVLATGARARE-PQIKGKEYLLTLRTIFDADRIKESIENSGEAIII 149 Query: 183 -----GMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVES 237 G+E L G V ++ L D ++S I+ ++ GV +++ Sbjct: 150 GGGFIGLELAGNLAEAGYHVKLIHRGAMFL-GLDEELSNMIKDMLEETGVKFFLNSELLE 208 Query: 238 IADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYM 297 + G +T G ++ + + AIG PNV+ ++G+ + I +DD Sbjct: 209 ANEEG-----VLTNSGF---IEGKVKICAIGIVPNVD--LARRSGIHTG--RGILIDDNF 256 Query: 298 RTNVGHIYAIGDVNGLLQL----AHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQP 353 RT+ +YAIGD + A A Q V A+ + G R F + Sbjct: 257 RTSAKDVYAIGDCAEYSGIIAGTAKAAMEQARVLADILKGEPRRYNFKFRS-TVFKFGKL 315 Query: 354 NVASFGLTEQQARNEGYDVVVAKFPFTANAKAHG 387 +A G T + EG + F N K G Sbjct: 316 QIAIIGNT----KGEGKWIEDNTKVFYENGKIIG 345 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 43/118 (36%), Gaps = 22/118 (18%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRAL---PNEDADVSKEIEKQ-------- 221 ++I G G G E L +VT+++ P P ++ I + Sbjct: 10 KVVIVGNGPGGFELAKQLSQT-YEVTVIDKEPVPYYSKPMLSHYIAGFIPRNRLFPYSLD 68 Query: 222 -FKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIG---FAPNVEG 275 ++K G+ I A + + I G V E+ + ++ A G P ++G Sbjct: 69 WYRKRGIEIRLAEEAKLIDRGRKVVITE------KGEVPYDTLVLATGARAREPQIKG 120 >6GAR-A nrPDB Length = 349 Score = 109 bits (272), Expect = 4e-24, Method: Composition-based stats. Identities = 61/343 (17%), Positives = 106/343 (30%), Gaps = 49/343 (14%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGGVCLNVGCIPSKALLRNAELVHIF 62 +DV V+G GP G +A + + T I+E + GG ++V P K + L+ + Sbjct: 7 FDVTVIGGGPAGLYSAFYSGLREMRTKIIEFHPHLGGK-IHVY--PEKMIWDVGGLLPVT 63 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 + +TF + D + G Sbjct: 64 GDKLIEQLVQQGLTFKPEVVLDTKVESIIRNQDG-------------------------T 98 Query: 123 VDLNDGGTESVTFDNAIIATGS---STRL--VPGTSLSANVVTYEEQILSRELPKSIIIA 177 L E I+ATGS + + G + +I Sbjct: 99 FTLKTSTGEEHFSKTVIVATGSGILKPQKLSIEGAERFEVSNLNYTVKSLKRFKGKTVII 158 Query: 178 -GAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVE 236 G G +++ L+ V + L +A V KQ T + Sbjct: 159 SGGGNSAVDWANELEPIAKKVYVTYRKEE-LSGHEAQV-----KQLMNSSAECFFNTSIT 212 Query: 237 SIADGGSQ-----VTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAI 291 + G + V +T + G L ++V+ G+ ++ + VA+ D I Sbjct: 213 KLIAGDNHEAIEYVELTNHETGEVSHLPIDEVIINHGYERDITLLENSELDVAIIDNYYI 272 Query: 292 GVDDYMRTNVGHIYAIGDV---NGLLQLAHVAEAQGVVAAETI 331 + ++V +YA GD+ G L L A A Sbjct: 273 AGNANSESSVDGLYAAGDILKHEGKLHLIAGAFQDAGNAVNKA 315 >3LZX-A nrPDB Length = 332 Score = 108 bits (270), Expect = 5e-24, Method: Composition-based stats. Identities = 57/348 (16%), Positives = 117/348 (33%), Gaps = 61/348 (17%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCL---------NVGCIPSKA 51 YD+ ++G GP G A S I+E GG +V P Sbjct: 6 KVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPK-- 63 Query: 52 LLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHG 111 +R EL++ + FD I +++ + E + GV L+ + Sbjct: 64 -IRAQELINNLKEQMAK--------FDQTICLEQAVESVEKQADGVFKLVTNEETHY--- 111 Query: 112 YGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVP---GTSLSANVVTYEEQILSR 168 + T+++ +G + R + + Y L + Sbjct: 112 ------SKTVIITAGNGAFK--------------PRKLELENAEQYEGKNLHYFVDDLQK 151 Query: 169 ELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVT 228 + + I G G +++ +L+ +V+I+ + +E + + V Sbjct: 152 FAGRRVAILGGGDSAVDWALMLEPIAKEVSIIHRRDKFRAHEHS------VENLHASKVN 205 Query: 229 ILTATKVESI--ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALT 286 +LT + D Q+ + K + L+ + ++ GF ++ G+ + Sbjct: 206 VLTPFVPAELIGEDKIEQLVLEEVKGDRKEILEIDDLIVNYGFVSSLGPI--KNWGLDI- 262 Query: 287 DRKAIGVDDYMRTNVGHIYAIGDV---NGLLQLAHVAEAQGVVAAETI 331 ++ +I V M TN+ +A GD+ G + L + A Sbjct: 263 EKNSIVVKSTMETNIEGFFAAGDICTYEGKVNLIASGFGEAPTAVNNA 310 >5MIU-A nrPDB Length = 535 Score = 108 bits (270), Expect = 5e-24, Method: Composition-based stats. Identities = 77/357 (21%), Positives = 135/357 (37%), Gaps = 66/357 (18%) Query: 19 AIRAAQLGLSTAIV-EPKYWGGVCLNVGCIP------SKALLRNAELVHIFTKDAKAF-G 70 +IRA G IV E P SK L + + T + + G Sbjct: 71 SIRARDPGARVLIVSEDPEL----------PYMRPPLSKELWFSDDPNVTKTLQFRQWNG 120 Query: 71 ISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGT 130 + F Y ++ + GV L K + D +V LNDG Sbjct: 121 KERSIYFQPPSFYVSAQDLPNIENGGVAVLTGKKVVH--------LDVRGNMVKLNDGS- 171 Query: 131 ESVTFDNAIIATGSSTRLVP-----GTSLSANVVTYEEQILSREL------PKSIIIAGA 179 +TF+ +IATG + R + G + + + + R L KSI + G Sbjct: 172 -QITFEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRALEKISREVKSITVIGE 230 Query: 180 GAIGMEFGYVL--KNYGVDVTIVEFLP------RALPNEDADVSKEIEKQFKKLGVTILT 231 G +G E L K+ + +++ P + LP +S ++ K+ GV ++ Sbjct: 231 GFLGSELACALGRKSQASGIEVIQLFPEKGNMGKILPQY---LSNWTMEKVKREGVKVMP 287 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALT-DRKA 290 V+S+ G ++ + KDG ++++ + ++ A+G PNVE G+ + D Sbjct: 288 NAIVQSVGVSGGRLLIK-LKDG--RKVETDHIVTAVGLEPNVE--LAKTGGLEIDSDFGG 342 Query: 291 IGVDDYMRTNVGHIYAIGDVN-------GLLQLAH--VAEAQGVVAAETIAGAETLT 338 V+ ++ +I+ GD G ++ H A G +A E + GA Sbjct: 343 FRVNAELQAR-SNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPY 398 >4YKF-A nrPDB Length = 521 Score = 108 bits (269), Expect = 7e-24, Method: Composition-based stats. Identities = 52/279 (18%), Positives = 92/279 (32%), Gaps = 22/279 (7%) Query: 67 KAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGY-GTFADANTLLVDL 125 + FG T D + + + + + + I + + L Sbjct: 243 ERFGGQILDTVDIENYISVPKTEGQKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGL 302 Query: 126 ND---GGTESVTFDNAIIATGS--STRLVPGT-SLSANVVTYEEQILSR-ELPKSIIIAG 178 + + + I+ATG+ VPG VTY K + + G Sbjct: 303 HQIETASGAVLKARSIIVATGAKWRNMNVPGEDQYRTKGVTYCPHCDGPLFKGKRVAVIG 362 Query: 179 AGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESI 238 G G+E L VT++EF P D + ++ V I+ + + Sbjct: 363 GGNSGVEAAIDLAGIVEHVTLLEFAPE--MKADQVLQDKLRSL---KNVDIILNAQTTEV 417 Query: 239 ADGGSQVTVTVTKD---GVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDD 295 GS+V +D G ++ + IG PN + V I +D Sbjct: 418 KGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWL---EGAVERNRMGEIIIDA 474 Query: 296 YMRTNVGHIYAIGDVNGLL--QLAHVAEAQGVVAAETIA 332 TNV ++A GD + Q+ +A +G A+ + Sbjct: 475 KCETNVKGVFAAGDCTTVPYKQII-IATGEGAKASLSAF 512 >4YRY-B nrPDB Length = 468 Score = 103 bits (258), Expect = 2e-22, Method: Composition-based stats. Identities = 71/350 (20%), Positives = 113/350 (32%), Gaps = 59/350 (16%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIFTK 64 V V+G+GP G AA A++G I E GG + V IP L +V Sbjct: 143 VAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGG--VLVYGIPEFRL--PKRIVEREVS 198 Query: 65 DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVD 124 + G V F ++ KV E + G F ++ Sbjct: 199 YIRKLG----VNFHLNTVVGKTVKVKELLSEYDAVFIGTGA-----GTPKFMGIPGTNLN 249 Query: 125 LNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGM 184 E +T N + A + E + K + + GAG M Sbjct: 250 GVYSANEFLTRVNLMKA-----------------YLFPEYDTPIRVGKKVAVIGAGNTAM 292 Query: 185 EFGYVLKNYGVD-VTIVEFL-PRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGG 242 + G + V IV R +P +E ++ G+ L T Sbjct: 293 DAARSALRLGAEKVYIVYRRTEREMPAR----REEYHHALEE-GIEFLWLTLPIRYIGDA 347 Query: 243 SQ-------VTVTVTKD------------GVAQELKAEKVLQAIGFAPNVEGYGLDKAGV 283 + V + + + G L+ + V++AIG PN + G+ Sbjct: 348 NGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPN-RVLLSEFPGL 406 Query: 284 ALTDRKAIGVDDY-MRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIA 332 L +R I D+ T+V ++A GD+ A G AA+ I Sbjct: 407 ELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIH 456 Score = 44.1 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 30/106 (28%), Gaps = 21/106 (19%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALP---------NEDADVSKEIEKQF 222 + + + G+G G+ L G V I E + + + Sbjct: 141 EKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYI 200 Query: 223 KKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIG 268 +KLGV T V G V V + + V G Sbjct: 201 RKLGVNFHLNTVV------GKTVKVKELLS------EYDAVFIGTG 234 >1FL2-A nrPDB Length = 310 Score = 103 bits (256), Expect = 2e-22, Method: Composition-based stats. Identities = 48/259 (18%), Positives = 83/259 (32%), Gaps = 19/259 (7%) Query: 67 KAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGY-GTFADANTLLVDL 125 + FG T D + + + + + + I + + L Sbjct: 32 ERFGGQILDTVDIENYISVPKTEGQKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGL 91 Query: 126 ND---GGTESVTFDNAIIATGS--STRLVPGT-SLSANVVTYEEQILSR-ELPKSIIIAG 178 + + + I+ATG+ VPG VTY K + + G Sbjct: 92 HQIETASGAVLKARSIIVATGAKWRNMNVPGEDQYRTKGVTYCPHCDGPLFKGKRVAVIG 151 Query: 179 AGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESI 238 G G+E L VT++EF P D + ++ V I+ + + Sbjct: 152 GGNSGVEAAIDLAGIVEHVTLLEFAPE--MKADQVLQDKLRSL---KNVDIILNAQTTEV 206 Query: 239 ADGGSQVTVTVTKD---GVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDD 295 GS+V +D G ++ + IG PN + V I +D Sbjct: 207 KGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWL---EGAVERNRMGEIIIDA 263 Query: 296 YMRTNVGHIYAIGDVNGLL 314 TNV ++A GD + Sbjct: 264 KCETNVKGVFAAGDCTTVP 282 >2WHD-A nrPDB Length = 351 Score = 100 bits (250), Expect = 1e-21, Method: Composition-based stats. Identities = 66/345 (19%), Positives = 112/345 (32%), Gaps = 66/345 (19%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP-----KYWGG---VCLNVGCIPS-KALLRNA 56 V ++G+GP + AAI AA+ L + E GG +V P + Sbjct: 33 VCIIGSGPAAHTAAIYAARAELKPVLFEGWMANDIAAGGQLTTTTDVENFPGFPTGIMGI 92 Query: 57 ELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFA 116 +L+ + FG + + V V F + ++T Sbjct: 93 DLMDNCRAQSVRFGTN----------------ILSETVTEVDFSARPFRVTS-------- 128 Query: 117 DANTLLVDLNDGGTESVTFDNAIIATGSSTRLV--PGTSLSANVVTYEEQILSRELP--- 171 D+ T+L D ++ATG+ R + G+ N + P Sbjct: 129 DSTTVL------------ADTVVVATGAVARRLYFSGSDTYWNRGISACAVCDGAAPIFR 176 Query: 172 -KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL 230 K I + G G ME G L YG V I+ ++ + + ++ Sbjct: 177 NKPIAVIGGGDSAMEEGNFLTKYGSQVYIIHRRNTFRASKIMQA-----RALSNPKIQVV 231 Query: 231 TATKVES-----IADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVAL 285 ++V + V V G +L+ + AIG P + + L Sbjct: 232 WDSEVVEAYGGAGGGPLAGVKVKNLVTGEVSDLQVSGLFFAIGHEPATKFL---NGQLEL 288 Query: 286 TDRKAIGVDD-YMRTNVGHIYAIGDVNG-LLQLAHVAEAQGVVAA 328 + T+V ++A GDV + A A G +AA Sbjct: 289 HADGYVATKPGSTHTSVEGVFAAGDVQDKKYRQAITAAGSGCMAA 333 >6GAS-A nrPDB Length = 331 Score = 99 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 57/337 (16%), Positives = 114/337 (33%), Gaps = 39/337 (11%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVH 60 YD+ ++G GP G A S I+E GG + P K + A Sbjct: 8 KVYDITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGGQLSALY--PEKYIYDVAGFPK 65 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120 + ++ FD + + + E + G+ F + NK T + + Sbjct: 66 VRAQELVDNLKEQMKKFDPTVCLEEAVDTLEKQADGI-FKLVTNKQTHY--------SKS 116 Query: 121 LLVDLNDGGTESVTFDNAIIATGSSTRLVPG-TSLSANVVTYEEQILSRELPKSIIIAGA 179 +++ +G + + G + Y +++ K +++ G Sbjct: 117 VIITAGNGAFQ------------PRRLELEGTAKYEKKNLHYFVDDMNKFAGKRVVVFGG 164 Query: 180 GAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESI- 238 G +++ +L+ VTIV + +E + + + T + Sbjct: 165 GDSAVDWTMMLEPIAEKVTIVHRRDKFRAHEHS------VENLMNSRAEVSTPYVPVELI 218 Query: 239 -ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYM 297 D QV + K + + V+ GF ++ G+ + + +I V+ M Sbjct: 219 GDDKIEQVVLQHVKTEEKVIIDVDDVIVNYGFVSSLGPI--KNWGLDIQ-KNSILVNSKM 275 Query: 298 RTNVGHIYAIGDV---NGLLQLAHVAEAQGVVAAETI 331 TN+ IYA GD+ G ++L + A Sbjct: 276 ETNIPGIYAAGDICTYEGKVKLIACGFGEAPTAVNNA 312 >5YGQ-A nrPDB Length = 342 Score = 98.8 bits (245), Expect = 4e-21, Method: Composition-based stats. Identities = 67/348 (19%), Positives = 117/348 (33%), Gaps = 62/348 (17%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGGVCLN------VGCIPSKALLRNAE 57 DV+++GAGP G A L + +V+ GG C + IP ++ Sbjct: 8 DVLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVGGQCAELYPEKPIYDIPGIPMVTGHG 67 Query: 58 LVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFAD 117 L + K F TF + K+ + Sbjct: 68 LTEALMEQIKPF----NPTFHLSEMVENVEKIGDPGFR---------------------- 101 Query: 118 ANTLLVDLNDGGTESVTFDNAIIATGS------STRLVPGTSLSANVVTYEEQILSRELP 171 V N G + ++A G + + V Y + + Sbjct: 102 -----VTTNAG--KVFECTVLVVAAGGGSFLPKRPPVPGVEAYEGTSVHYAVRKMEDFRG 154 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP--RALPNEDADVSKEIEKQFKKLGVTI 229 K I+I G G +++ L +T+V R P+ + + + KL + I Sbjct: 155 KDILIVGGGDSALDWTLNLNPIAKSMTLVHRRDDFRGAPHSVEQMRQLVAS--GKLDLKI 212 Query: 230 LTATKVESIADGGSQVTVTVTK--DGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTD 287 ++ + Q+T K D ++K + +L G ++ + G+ L + Sbjct: 213 ---GQITELQGDNGQLTGATVKLNDNTTSQIKCDAMLPFFGLT--MKLGPVANWGLDL-E 266 Query: 288 RKAIGVDD-YMRTNVGHIYAIGDVN---GLLQLAHVAEAQGVVAAETI 331 I VD TNV I+AIGD+N G L+L +G + A+ Sbjct: 267 NNLIPVDTGTFETNVPGIFAIGDINTYPGKLKLILSGFHEGALMAQKA 314 >5VJ7-A nrPDB Length = 476 Score = 98.1 bits (243), Expect = 7e-21, Method: Composition-based stats. Identities = 71/364 (19%), Positives = 116/364 (31%), Gaps = 89/364 (24%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIFTK 64 V ++GAGP G A A++G I E GG + IP L E++ K Sbjct: 157 VAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGG--VLTYGIPEFRL--PKEILRKELK 212 Query: 65 DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVD 124 G+ + G + E Sbjct: 213 KLSLLGVEIKTDHIVGKTITIQELLQE--------------------------------- 239 Query: 125 LNDGGTESVTFDNAIIATGSSTRLVPGTS-LSANVVTYEEQILSR-------ELPK---- 172 +D I TG+ T +P ++ N + + L+R + P+ Sbjct: 240 ----------YDAVFIGTGAGTPKLPNIPGINLNGIYSANEFLTRINLMKAYKFPEYDTP 289 Query: 173 -----SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGV 227 +++ GAG M+ G +VTI R ED E K ++ GV Sbjct: 290 IVVGKKVVVIGAGNTAMDAARSALRLGAEVTIAYRRGR----EDMTARIEEVKHAEEEGV 345 Query: 228 TILTATK-VESIADGGSQVTVTVTK------------------DGVAQELKAEKVLQAIG 268 + VE I D V + G ++A+ V+ AIG Sbjct: 346 KFMFFVNPVEFIGDENGNVKAVKFEKMKPLEERDSRGKRKIVGTGEYITVEADTVIIAIG 405 Query: 269 FAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAA 328 PN + + + + I VD+ + T++ ++A GD +A G AA Sbjct: 406 QTPN-KVLWRATPELKVDEWGRIVVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAA 464 Query: 329 ETIA 332 + I Sbjct: 465 KAIH 468 Score = 47.2 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 30/136 (22%), Positives = 47/136 (34%), Gaps = 25/136 (18%) Query: 156 ANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALP------- 208 + + EE + K + I GAG G+ L G +VTI E L + Sbjct: 139 DDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLTYGIP 198 Query: 209 --NEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQA 266 ++ ++ K+ LGV I T V G +T+ + + V Sbjct: 199 EFRLPKEILRKELKKLSLLGVEIKTDHIV------GKTITI------QELLQEYDAVFIG 246 Query: 267 IGFA----PNVEGYGL 278 G PN+ G L Sbjct: 247 TGAGTPKLPNIPGINL 262 >5TWC-A nrPDB Length = 344 Score = 93.4 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 51/334 (15%), Positives = 104/334 (31%), Gaps = 37/334 (11%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 DV ++G GP G A+ A +S +++ GG P K + + Sbjct: 3 DVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGGKMR---IYPEKIIWDIGGIAPKPC 59 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV 123 + I + F + + + HF ++ ++ Sbjct: 60 HEILKDTIKQGLYFKPEVHLNERVVDIRKKAER-HFEVETEAGEIYTSKAVIIAIGAGII 118 Query: 124 DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIG 183 + + V + Y Q R K ++I+G G Sbjct: 119 NPKQLDVKGVE------------------RYQLTNLHYVVQSYRRFKDKDVLISGGGNTA 160 Query: 184 MEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGS 243 +++ + + VT+V ED + ++ L V + T+++ + Sbjct: 161 LDWAHDIAKIAKSVTVVYR------KEDVSGHEAMKTLVTDLNVKLCPKTRIKYLVGNDD 214 Query: 244 -----QVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMR 298 +V + + G +K + V+ + GF + + + D + Sbjct: 215 ETHISEVVLEHVESGDRHTVKFDDVIISHGFDRCNTLLSETSSKLDMHDDCRVKGFGNTT 274 Query: 299 TNVGHIYAIGDVN---GLLQLAHVAEAQGVVAAE 329 T++ IYA GD+ L A + G AA Sbjct: 275 TSIPGIYACGDIVYHDAKSHLIASAFSDGANAAN 308 >2VDC-G nrPDB Length = 456 Score = 81.5 bits (200), Expect = 8e-16, Method: Composition-based stats. Identities = 45/239 (18%), Positives = 79/239 (33%), Gaps = 45/239 (18%) Query: 138 AIIATG---SSTRLVPGTSLS-----------------ANVVTYEEQILSRELPKSIIIA 177 ++ATG + PG+ L + V E K +++ Sbjct: 211 VLVATGVYKARDIKAPGSGLGNIVAALDYLTTSNKVSLGDTVEAYENGSLNAAGKHVVVL 270 Query: 178 GAGAIGMEFGYVLKNYGV-DVTIVEFLPRA-LPNEDADVSKEIEKQFKKLGVTILTATKV 235 G G M+ G V + R +P +V+ ++ GV + Sbjct: 271 GGGDTAMDCVRTAIRQGATSVKCLYRRDRKNMPGSQREVA-----HAEEEGVEFIWQAAP 325 Query: 236 ES-----IADGGSQVTVTVTKD------------GVAQELKAEKVLQAIGFAPNVEGYGL 278 E + G V + + G ++A+ V++A+GF P Sbjct: 326 EGFTGDTVVTGVRAVRIHLGVADATGRQTPQVIEGSEFTVQADLVIKALGFEPEDLPNAF 385 Query: 279 DKAGVALTDRKAIGVDDYMR-TNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAET 336 D+ + +T + VD + TN+ ++A GD+ L A G AAE I Sbjct: 386 DEPELKVTRWGTLLVDHRTKMTNMDGVFAAGDIVRGASLVVWAIRDGRDAAEGIHAYAK 444 >4G74-A nrPDB Length = 502 Score = 78.8 bits (193), Expect = 4e-15, Method: Composition-based stats. Identities = 50/298 (16%), Positives = 98/298 (32%), Gaps = 65/298 (21%) Query: 97 VHFLMKKNK-ITEIHGYGTFA--DANTLLVDLNDGGTE----------------SVTFDN 137 V+F +KK +T T D NT+ + ++ + +D Sbjct: 101 VNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDY 160 Query: 138 AIIATGSSTRL--VPGTSLSANVV-----------TYEEQILSRE-LPK------SIIIA 177 I A G+ +PG + + + T+ + LPK ++ Sbjct: 161 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 220 Query: 178 -----------GAG----AIGMEFGYVLKNYGVDV--TIVEFLPRALPNEDADVSKEIEK 220 AG + + L +V +VE LP L + +S + Sbjct: 221 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQS 280 Query: 221 QFKKLGVTILTATKVESIADGGSQVTVTVTKDGV--AQELKAEKVLQAIG--FAPNVEGY 276 + + + T V + + +DG + + ++ A G P + Sbjct: 281 HLENTSIKVHLRTAVAKVEEKQLLAKTKH-EDGKITEETIPYGTLIWATGNKARPVITDL 339 Query: 277 GLDKAGVALTDRKAIGVDDYMRTN-VGHIYAIGDV--NGLLQLAHVAEAQGVVAAETI 331 K + ++ + V+D+++ +I+AIGD GL A VA + A+ Sbjct: 340 -FKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNF 396 >5NA1-A nrPDB Length = 408 Score = 77.3 bits (189), Expect = 1e-14, Method: Composition-based stats. Identities = 64/306 (20%), Positives = 104/306 (33%), Gaps = 57/306 (18%) Query: 90 AEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLV 149 E + V ++KK+K+ + T D + V+ N G FD ++A G + Sbjct: 66 YEDVLYPVESVLKKDKVNFVQAEVTKIDRDAKKVETNQG---IYDFDILVVALGFVSETF 122 Query: 150 PGTSLSANVVTYEEQILSRELPKSI--------------------IIAGAGAIGMEFGYV 189 + + E I +REL + I ++ GAG G+EF Sbjct: 123 GIEGMKDHAFQIENVITARELSRHIEDKFANYAASKEKDDNDLSILVGGAGFTGVEFLGE 182 Query: 190 LKNY-------------GVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVE 236 L + V +T VE P+ LP ++ + GV AT + Sbjct: 183 LTDRIPELCSKYGVDQNKVKITCVEAAPKMLPMFSEELVNHAVSYLEDRGVEFKIATPIV 242 Query: 237 SIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDY 296 + + G V V DG Q+L A + A G G L + R I Sbjct: 243 ACNEKGFVVEV----DGEKQQLNAGTSVWAAGVR----GSKLMEESFEGVKRGRIVTKQD 294 Query: 297 MRTN-VGHIYAIGDVNGLLQ---------LAHVAEAQGVVAAETIA---GAETLTLGDHR 343 + N +I+ IGD + + A +A QG A+ I E+ ++ Sbjct: 295 LTINGYDNIFVIGDCSAFIPAGEERPLPTTAQIAMQQGESVAKNIKRILNGESTEEFEYV 354 Query: 344 MLPRAT 349 Sbjct: 355 DRGTVC 360 Score = 32.6 bits (73), Expect = 0.42, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 37/121 (30%), Gaps = 24/121 (19%) Query: 172 KSIIIAGAGAIGM------------EFGYVL----KNYGVDVTIVEFLPRALPNEDADVS 215 K +++ GAG G+ E + Y + T + N DV Sbjct: 12 KKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYHYEATWLHEASAGTLNY-EDVL 70 Query: 216 KEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEG 275 +E KK V + +V I +V + ++ A+GF G Sbjct: 71 YPVESVLKKDKVNFV-QAEVTKIDRDAKKVET------NQGIYDFDILVVALGFVSETFG 123 Query: 276 Y 276 Sbjct: 124 I 124 >5JWC-A nrPDB Length = 521 Score = 71.1 bits (173), Expect = 9e-13, Method: Composition-based stats. Identities = 37/217 (17%), Positives = 71/217 (32%), Gaps = 43/217 (19%) Query: 135 FDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKS--------------------- 173 +D IIA G+ T + ++ + ++ K Sbjct: 129 YDYLIIAVGAKTNTFNINGVDKYAYFVKDIDDALKIRKKFLDILEKCTLPNISNEEKKKM 188 Query: 174 --IIIAGAGAIGMEF-GYVLKNYGVDVTI-------------VEFLPRALPNEDADVSKE 217 + + G G G+E +V I +E LP ++S Sbjct: 189 LHVAVVGGGPTGVEVTAEFADFINKEVKINYKDIFNFISISIIEGGNNLLPTFTQNISDF 248 Query: 218 IEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYG 277 ++ F L + +LT V + + ++ K+ ++L ++ A G Sbjct: 249 TKENFHNLNINVLTNYYVIDVDKHSFHIQSSLNKN-EKKKLSYGLLIWASGL-AQTTLIQ 306 Query: 278 LDKAGVALTDRKAI-GVDDYMRT-NVG--HIYAIGDV 310 + + AI VD+ +R + +IYAIGD Sbjct: 307 KFLKTIPVQANNAILKVDEKLRVIGIPSNNIYAIGDC 343 >3H8L-A nrPDB Length = 409 Score = 62.6 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 47/307 (15%), Positives = 93/307 (30%), Gaps = 59/307 (19%) Query: 90 AEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV--DLNDGGTESVTFDNAIIATGSSTR 147 + + + + I G DA + +V DG +D I+ G+ Sbjct: 55 VDELKVDLSEALPEKGIQFQEGTVEKIDAKSSMVYYTKPDGSMAEEEYDYVIVGIGAHLA 114 Query: 148 LVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGM----------------------- 184 + E + +L + + G I + Sbjct: 115 TELVKGWDKYGYSVCEPEFATKLREKLESFQGGNIAIGSGPFYQGHNPKPKVPENFVPNA 174 Query: 185 ---------EFGYVLKNY--------GVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGV 227 E +L Y V VT+ L + + K + + +LG+ Sbjct: 175 DSACEGPVFEMSLMLHGYFKKKGMLDKVHVTVFSPGEY-LSDLSPNSRKAVASIYNQLGI 233 Query: 228 TILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVAL-T 286 ++ K++ I + D + A+ + P L + L Sbjct: 234 KLVHNFKIKEIRE-------HEIVDEKGNTIPADITIL---LPPYTGNPALKNSTPDLVD 283 Query: 287 DRKAIGVDDYMRTNVG--HIYAIGDVNGL--LQLAHVAEAQGVVAAETIAGAETLTLGDH 342 D I D M ++ ++YA+GD N + +L ++A G +AA+ +A + Sbjct: 284 DGGFIPTDLNM-VSIKYDNVYAVGDANSMTVPKLGYLAVMTGRIAAQHLANRLGVPTKVD 342 Query: 343 RMLPRAT 349 + P Sbjct: 343 KYYPTIV 349 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 42/116 (36%), Gaps = 16/116 (13%) Query: 173 SIIIAGAGAIGMEFGYVLKNY---GVDVTIV-----EFLPRALP------NEDADVSKEI 218 +++ G + Y LK DV ++ + ALP + ++ ++ Sbjct: 3 KVLVLGGRFGALTAAYTLKRLVGSKADVKVINKSRFSYFRPALPHVAIGVRDVDELKVDL 62 Query: 219 EKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVE 274 + + G+ T VE I D S + DG E + + V+ IG E Sbjct: 63 SEALPEKGIQFQEGT-VEKI-DAKSSMVYYTKPDGSMAEEEYDYVIVGIGAHLATE 116 >1PS9-A nrPDB Length = 671 Score = 62.2 bits (150), Expect = 4e-10, Method: Composition-based stats. Identities = 51/308 (16%), Positives = 83/308 (26%), Gaps = 95/308 (30%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-YWGGVCLNVGCIPSKALLRNAELVHIFTK 64 + V+GAGP G AI AA G + + GG IP K Sbjct: 376 LAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYET-------- 427 Query: 65 DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVD 124 + +++ +T +T+ D Sbjct: 428 -----------------------------LRYYRRMIEVTGVT-------LKLNHTVTAD 451 Query: 125 LNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELP--KSIIIAGAGAI 182 FD I+A+G R P + V +L + P + I G G I Sbjct: 452 QLQA------FDETILASGIVPRTPPIDGIDHPKVLSYLDVLRDKAPVGNKVAIIGCGGI 505 Query: 183 GME---------------FGYVLKNYGVDVTI-----VEFLPRALPNEDADVSKEIEKQ- 221 G + +G+D ++ + +P + K Sbjct: 506 GFDTAMYLSQPGESTSQNIAGFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVMLQRKAS 565 Query: 222 -----------------FKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVL 264 GV ++ + I D G V + +G Q L + V+ Sbjct: 566 KPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDDDGLHVVI----NGETQVLAVDNVV 621 Query: 265 QAIGFAPN 272 G PN Sbjct: 622 ICAGQEPN 629 Score = 41.4 bits (96), Expect = 9e-04, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 42/102 (41%), Gaps = 6/102 (5%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 K++ + GAG G+ F G VT+ + +++K+I + ++ T+ Sbjct: 374 KNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQF--NIAKQIPGK-EEFYETLRY 430 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNV 273 ++ + ++ TVT D Q ++ + A G P Sbjct: 431 YRRMIEVTGVTLKLNHTVTAD---QLQAFDETILASGIVPRT 469 >4NTC-A nrPDB Length = 335 Score = 61.8 bits (149), Expect = 7e-10, Method: Composition-based stats. Identities = 60/337 (17%), Positives = 101/337 (29%), Gaps = 51/337 (15%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTK 64 DV+++GAGP G A A+ + + + + RNA+ H+ Sbjct: 16 DVLIIGAGPAGLSTATGLARQLHTAVVFDSGVY----------------RNAKTQHMHN- 58 Query: 65 DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVD 124 G + R+ A+ + + I I L + Sbjct: 59 ---VLGWDHRNPAEL-----RAAGRADLTTRYSTIQFQNSTIEAIR-----QVETNQLFE 105 Query: 125 LNDGGTESVTFDNAIIATGSS--TRLVPGTSLSANVVTYEEQILSRELP---KSIIIAGA 179 D S ++ATG + G S Y +++ + Sbjct: 106 ARDNEGHSWYGRKVVLATGVRDIPLDIEGYSECWANGIYHCLFCDGYEERGQETVGVLAL 165 Query: 180 GAIG-----MEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATK 234 G I + + VTI L E ++E G+ A Sbjct: 166 GPIANPARALHLARMALRLSESVTIYTNGNEQLAKEIQQAAEE--SPVGASGLKF-EARP 222 Query: 235 VESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYG--LDKAGVALTDRKAIG 292 + G TV V E K E L P E G + + +T+ I Sbjct: 223 IRRFEKGDVAKTVIVHLG--ESESKTEGFLVY---NPQTEVNGPFAKQLALNMTEGGDIL 277 Query: 293 VDD-YMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAA 328 + T+V ++A+GD L+ A + G +AA Sbjct: 278 TTPPFYETSVPGVFAVGDCATPLKAVTPAVSMGSLAA 314 >4FK1-A nrPDB Length = 304 Score = 59.5 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 52/335 (15%), Positives = 101/335 (30%), Gaps = 53/335 (15%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH 60 M + D V+GAGP G A++ + A+ + + Sbjct: 4 MKYIDCAVIGAGPAGLNASLVLGRARKQIALFDNNT---------------------NRN 42 Query: 61 IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADAN- 119 T+++ F K E + G++ +MK + Sbjct: 43 RVTQNSHGF------------ITRDGIKPEEFKEIGLNEVMKYPSVHYYEKTVVMITKQS 90 Query: 120 TLLVDLNDGGTESVTFDNAIIATGSS---TRLVPGTSLSANVVTYEEQILSRELPKSIII 176 T L ++ + ++ATG + + EL +I Sbjct: 91 TGLFEIVTKDHTKYLAERVLLATGMQEEFPSIPNVREYYGKSLFSCPYCDGWELKDQPLI 150 Query: 177 AGAGAIGMEFGYVLKNYGVDVTIVE--FLPRALPNEDADVSKEIEKQFKKLGVTILTATK 234 I + L +V + ++S+ I + + ++T + Sbjct: 151 I----ISENEDHTLHM----TKLVYNWSTDLVIATNGNELSQTIMDELSNKNIPVITESI 202 Query: 235 VESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVD 294 +GG V + +A + F PN +++ G L +D Sbjct: 203 RTLQGEGGYLKKVEFHSGLRIE--RAGGFIVPTFFRPN---QFIEQLGCELQSNGTFVID 257 Query: 295 DYMRTNVGHIYAIGDVNG-LLQLAHVAEAQGVVAA 328 D+ RT+ +IY G+ +A +QG AA Sbjct: 258 DFGRTSEKNIYLAGETTTQGPSSLIIAASQGNKAA 292 >2TMD-A nrPDB Length = 729 Score = 55.3 bits (132), Expect = 6e-08, Method: Composition-based stats. Identities = 62/369 (16%), Positives = 111/369 (30%), Gaps = 84/369 (22%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGGVCLNVGCIPSKALLRNAELVHIFTK 64 V+++GAGP G AA + G + + + + GG V +P Sbjct: 392 VLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHLNQVAALPG--------------- 436 Query: 65 DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVD 124 + R + L+KKNK +++ + D Sbjct: 437 ------------------LGEWSYHRDYRETQITKLLKKNKESQLA-----LGQKPMTAD 473 Query: 125 LNDGGTESVTFDNAIIATGSS----------TRLVPGTSLSANVVTYEEQILS--RELPK 172 D IIATG+ +PG S EQ++ +++ K Sbjct: 474 ----DVLQYGADKVIIATGARWNTDGTNCLTHDPIPGADASLPDQLTPEQVMDGKKKIGK 529 Query: 173 SIIIAGAG--AIGMEFGYVLKNYGVDVTIVEFLP-----RALPNEDADVSKEIEKQFKKL 225 ++I A + L G +VTIV + + + E ++L Sbjct: 530 RVVILNADTYFMAPSLAEKLATAGHEVTIVSGVHLANYMHFTLEYPNMMRRLHELHVEEL 589 Query: 226 GVTI---LTATKVESIADGGSQVTVTVTKDGVAQE--------LKAEKVLQAIGFAPNVE 274 G + ++E G T GV+ ++ + ++ G Sbjct: 590 GDHFCSRIEPGRMEIYNIWGDGSKRTYRGPGVSPRDANTSHRWIEFDSLVLVTGRHSECT 649 Query: 275 GYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGA 334 + KA ++ ++ IY IGD +L A G A I A Sbjct: 650 LWNELKA----------RESEWAENDIKGIYLIGDAEA-PRLIADATFTGHRVAREIEEA 698 Query: 335 ETLTLGDHR 343 ++ Sbjct: 699 NPQIAIPYK 707 Score = 44.5 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 34/241 (14%), Positives = 72/241 (29%), Gaps = 46/241 (19%) Query: 163 EQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKE----- 217 E+ + S++I GAG G E VL G V + + + + + + Sbjct: 381 EKFRQTKNKDSVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHLNQVAALPGLGEW 440 Query: 218 -IEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGY 276 + +++ +T L + + + + A+KV+ A G N +G Sbjct: 441 SYHRDYRETQITKLL----KKNKESQLALGQKPMTADDVLQYGADKVIIATGARWNTDGT 496 Query: 277 GLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAET 336 + + D + QL G + Sbjct: 497 NC----LTHDP-------------IPG----ADASLPDQLTPEQVMDG---------KKK 526 Query: 337 LTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVK 396 + + F P++A ++ G++V + AN + P+ + Sbjct: 527 IGKRVVILNADTYFMAPSLA------EKLATAGHEVTIVSGVHLANYMHFTLEYPNMMRR 580 Query: 397 L 397 L Sbjct: 581 L 581 >2CVJ-A nrPDB Length = 180 Score = 53.8 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 30/158 (18%), Positives = 55/158 (34%), Gaps = 26/158 (16%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNE----------DADVSKEIEKQF 222 +I+ G G G+ L G+ V +++ + D +E+ ++ Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLKVLVLDGGRSKVKGVSRVPNYPGLLDEPSGEELLRRL 62 Query: 223 KKL----GVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGL 278 + G + V+ + D G V + KAE++L P + Sbjct: 63 EAHARRYGAEVRPGV-VKGVRDMGGVFEVETEEG----VEKAERLLLCTHKDPTLPSL-- 115 Query: 279 DKAGVALTDRK-AIGVDDYMRTNVGHIYAIGDVNGLLQ 315 + LT R I D+ RT+ +YA G G + Sbjct: 116 ----LGLTRRGAYIDTDEGGRTSYPRVYAAGVARGKVP 149 Score = 44.1 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 6/81 (7%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALL----RNAELVH 60 DV+V+G GP G AA+ A+ GL +++ V +P+ L EL+ Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLKVLVLDGGR--SKVKGVSRVPNYPGLLDEPSGEELLR 60 Query: 61 IFTKDAKAFGISGEVTFDYGI 81 A+ +G G+ Sbjct: 61 RLEAHARRYGAEVRPGVVKGV 81 >3UP5-A nrPDB Length = 545 Score = 53.4 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 41/247 (16%), Positives = 71/247 (28%), Gaps = 33/247 (13%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY-WGGVCLNVGCIPSKALLRNAELVH-IF 62 D VV+GAG G A Q G+ +E GG Sbjct: 11 DAVVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGGT------------WYWNRYPGCRL 58 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGY-----GTFAD 117 ++ A+G + + + V+ + + + + Sbjct: 59 DTESYAYGYFALKGIIPEWEWSENFASQPEMLRYVNRAADAMDVRKHYRFNTRVTAARYV 118 Query: 118 ANTLLVDLNDGGTESVTFDNAIIATG----SSTRLVPGTS-LSANVVTYEEQILSRE--- 169 N L ++ E VT I ATG S + G E Sbjct: 119 ENDRLWEVTLDNEEVVTCRFLISATGPLSASRMPDIKGIDSFKGESFHSSRWPTDAEGAP 178 Query: 170 -----LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP-RALPNEDADVSKEIEKQFK 223 K + + G GA G++ + ++ + + P P ++ +SKE + Sbjct: 179 KGVDFTGKRVGVIGTGATGVQIIPIAAETAKELYVFQRTPNWCTPLGNSPMSKEKMDSLR 238 Query: 224 KLGVTIL 230 TIL Sbjct: 239 NRYPTIL 245 >5J7X-A nrPDB Length = 549 Score = 52.2 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 40/234 (17%), Positives = 79/234 (33%), Gaps = 40/234 (17%) Query: 3 HYDVVVLGAG-PGGYVAAIRAAQLGLSTAIVEPKY-WGGVCLN-------VGC-IPSKAL 52 H D +++G+G G Y+ +L L I E + GG N V C +P Sbjct: 12 HLDALIIGSGFSGIYLLHKLRDELKLKVKIFEAESDIGGTWNNNRYPGARVDCPVP---- 67 Query: 53 LRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHG- 111 L ++ ++++ Y +++ + V ++ K H Sbjct: 68 FYAYSLPEVWQ------------SWNWTELYPNQKEI-KSYFDHVDRVLDVRKDCLFHSR 114 Query: 112 --YGTFADANTLLVDLNDGGTESVTFDNAIIATG-SSTRLVPG----TSLSANVVTYEEQ 164 GTF D T + + T ++A G +S +P S + Sbjct: 115 VNEGTF-DEATGRWTVWTTDGKVATAKYLLVAVGFASKSYLPDWKGLDSFKGTIYHSAHW 173 Query: 165 ILSRELP---KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPR-ALPNEDADV 214 + E+ K + + G G+ G++ + + + P LP ++ Sbjct: 174 PEAEEISVKGKKVAVIGTGSTGIQIFQEWAREAEEAFLFQRTPNLCLPMRQQEL 227 >1NAA-A nrPDB Length = 541 Score = 51.8 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 5/44 (11%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW-----GGV 40 T YD +++GAGPGG +AA R ++ G ++E GG Sbjct: 1 TPYDYIIVGAGPGGIIAADRLSEAGKKVLLLERGGPSTKQTGGT 44 >3HYW-A nrPDB Length = 430 Score = 51.4 bits (122), Expect = 8e-07, Method: Composition-based stats. Identities = 44/248 (17%), Positives = 89/248 (35%), Gaps = 42/248 (16%) Query: 100 LMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSA--- 156 L+ K I I+ D + V G + + +D +IATG +LV G Sbjct: 65 LLPKFNIEFINEKAESIDPDANTVTTQSG--KKIEYDYLVIATG--PKLVFGAEGQEENS 120 Query: 157 -NVVTYEEQILSRELPKSI------IIAGA--GAI----GMEFGYVLK--------NYGV 195 ++ T E + +++ + + ++ GA G EF +L Y V Sbjct: 121 TSICTAEHALETQKKLQELYANPGPVVIGAIPGVSCFGPAYEFALMLHYELKKRGIRYKV 180 Query: 196 DVTIVEFLPRALPNEDADVSK---EIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKD 252 +T + P + +E F + + + V++I + + Sbjct: 181 PMTFITSEPYLGHFGVGGIGASKRLVEDLFAERNIDWIANVAVKAIEPDK---VIYEDLN 237 Query: 253 GVAQELKAEKVLQAIGFAPNVEGYGLDKA---GVALTDRKAIGVDD-YMRTNVGHIYAIG 308 G E+ A+ + F P+ +G + + VA K + V+ + +I+ +G Sbjct: 238 GNTHEVPAKFTM----FMPSFQGPEVVASAGDKVANPANKMVIVNRCFQNPTYKNIFGVG 293 Query: 309 DVNGLLQL 316 V + + Sbjct: 294 VVTAIPPI 301 >5NMX-A nrPDB Length = 425 Score = 51.1 bits (121), Expect = 9e-07, Method: Composition-based stats. Identities = 41/207 (19%), Positives = 65/207 (31%), Gaps = 15/207 (7%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGGVCLNVGCI---PSKALLRNAELVHI 61 V VLGAGP G AA Q G + E + GG + ++ ++ Sbjct: 4 VAVLGAGPSGLTAARYLKQAGFEVMVFERYHHVGGTWNYTDETWMSEDGRPVYSSMYQNL 63 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT- 120 F K + F K K+ ++ + Sbjct: 64 FVNLPKELMAFPDFPFHDIEGSYVPSKEVLKYFDNFTDAFDLRKLIKLQHHVENVRPCES 123 Query: 121 ---LLV-DLNDGGTESVTFDNAIIATGSS----TRLVPGTSLSANVVTYEEQILSRELP- 171 + V DL S FD ++ TG + V G S +T+ + S E Sbjct: 124 GWLVTVTDLTTMVEHSFEFDAVVVCTGQTWCPLYPDVEGRSFFRGRLTHAHEFRSPEPFR 183 Query: 172 -KSIIIAGAGAIGMEFGYVLKNYGVDV 197 K ++I GAG G + + +V Sbjct: 184 NKRVLIVGAGPSGHDMALHISYVSKEV 210 Score = 33.7 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 15/35 (42%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 + + + GAG G+ LK G +V + E Sbjct: 2 RRVAVLGAGPSGLTAARYLKQAGFEVMVFERYHHV 36 >4C5O-A nrPDB Length = 357 Score = 51.1 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 52/334 (15%), Positives = 93/334 (27%), Gaps = 69/334 (20%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY-WGGVCLNVGCIPSKALLRNAELV 59 M DVVV+G G G A + GLS I++ + GG + Sbjct: 1 MDSVDVVVIGGGQSGLSAGYFLRRSGLSYVILDAEASPGG---------------AWQHA 45 Query: 60 HIFTKDAKAFGISGEVTFDYGIAY-------DRSRKVAEGRVAGVHFLMKKNKITEIHGY 112 G S + + + +A+ +++ ++ + + Sbjct: 46 WHSLHLFSPAGWSSIPGWPMPASQGPYPARAEVLAYLAQYEQKYALPVLRPIRVQRVSHF 105 Query: 113 GTFADANTLLVDLNDGGTESVTFDNAIIATGSS-----TRLVPGTSLSANVVTYEEQILS 167 G L V DG I ATG+ S + + Sbjct: 106 GE-----RLRVVARDG--RQWLARAVISATGTWGEAYTPEYQGLESFAGIQLHSAHYSTP 158 Query: 168 RELPK-SIIIAGAGAIGMEFGYVLKNYG--VDVTIVEFLPRALPNEDADVSKEIEKQFKK 224 + I G G G +L + T + A +D D E+ ++ Sbjct: 159 APFAGMRVAIIGGGNSG---AQILAEVSTVAETTWITRTEPAFLADDVDGRVLFERATER 215 Query: 225 ----------------LGVTILTATKVESIADGGSQVT---VTVTKDG----VAQELKAE 261 G ++ +++ A G + G E + Sbjct: 216 WKAQQEGREPDLPPGGFGDIVMVPPVLDARARGVLAAVPPPARFSPTGMQWADGTERAFD 275 Query: 262 KVLQAIGFAPNVEGYGLDKAGVAL-TDRKAIGVD 294 V+ GF P + G+ L T + + VD Sbjct: 276 AVIWCTGFRPALSHL----KGLDLVTPQGQVEVD 305 >4USR-A nrPDB Length = 361 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 56/337 (16%), Positives = 104/337 (30%), Gaps = 55/337 (16%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIV-EPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 DV+V+G G A + LS ++ E GG A L + + +F+ Sbjct: 9 DVIVIGGGQAALTTAYFLRRTSLSYLLLDEQPGPGG-----------AWLHAWDSLRLFS 57 Query: 64 KDA--KAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTL 121 A G + G R+ + R + + + D + Sbjct: 58 PAAWSSIAGWPMPSPTEPG-NPTRNDVIDYLRRYEDRYQFPIQRPVRVDTVTRLDDLWRV 116 Query: 122 LVDLNDGGTESVTFDNAIIATG--SSTRLVP--GTSLSANVVTYEEQIL--SRELPKSII 175 G + I ATG S + P G L + + K ++ Sbjct: 117 Q-----AGDQQWLARAVISATGTWSKPFIPPYEGRELFQGAQIHSAHYRTPAPFAGKRVM 171 Query: 176 IAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNED------ADVSKEIEKQFKKLGVT- 228 + G G G + L + + I + P LP+E + + Q + + Sbjct: 172 VVGGGNSGAQVLAELSSVSETLWITQEPPAFLPDEVDGRVLFERATARWKAQQEGRSIDE 231 Query: 229 --------ILTATKVESIADGGSQV---------TVTVTKDGVAQELKAEKVLQAIGFAP 271 ++ E+ G T DG + L + V+ GF P Sbjct: 232 PAGGFGDIVMVPPVREARERGVLVAERPFARFTETGVEWADGRRENL--DAVIWCSGFRP 289 Query: 272 NVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIG 308 ++ L + GV + + V+D +++ +G Sbjct: 290 ALD--HLRELGV-VEADGKVQVEDTRVVKQPNLWLVG 323 >4OVI-A nrPDB Length = 542 Score = 50.3 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 38/244 (15%), Positives = 77/244 (31%), Gaps = 25/244 (10%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLR-----NAELV 59 DV+V+GAG G A R +LG S ++E +VG + A Sbjct: 18 DVLVVGAGFSGLYALYRLRELGRSVHVIE------TAGDVGGV-----WYWNRYPGARCD 66 Query: 60 HIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHG-YGTFADA 118 + +F +++ Y ++ ++ IT D Sbjct: 67 IESIEYCYSFSEEVLQEWNWTERYASQPEILRYINFVADKFDLRSGITFHTTVTAAAFDE 126 Query: 119 NTLLVDLNDGGTESVTFDNAIIATG--SSTRLVPGTSLSANVVTYEEQILSRELP----- 171 T ++ + + I+A+G S +L L P Sbjct: 127 ATNTWTVDTNHGDRIRARYLIMASGQLSVPQLPNFPGLKDFAGNLYHTGNWPHEPVDFSG 186 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA-LPNEDADVSKEIEKQFKKLGVTIL 230 + + + G G+ G++ + ++ + + P +P +A + E KK Sbjct: 187 QRVGVIGTGSSGIQVSPQIAKQAAELFVFQRTPHFAVPARNAPLDPEFLADLKKRYAEFR 246 Query: 231 TATK 234 ++ Sbjct: 247 EESR 250 >4TLZ-A nrPDB Length = 443 Score = 49.5 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 42/114 (36%), Gaps = 11/114 (9%) Query: 103 KNKITEIH-GYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTY 161 +++T I G G D+ + V + T +V N +I+TG R+ G V Sbjct: 144 DSEVTAIRPGPGRPVDSVLVDVSTPEA-TRTVEARNIVISTGLVPRMPAGVQSDEFVWHS 202 Query: 162 EEQIL-----SRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNE 210 + + + +AG G E L + D T+V +P+ Sbjct: 203 SRFLDHFRDRDPRSLRRVAVAGGGQSAAEIVRFLHDNRPD-TVVHA---IMPSY 252 >5BR7-A nrPDB Length = 393 Score = 46.8 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 2/41 (4%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAA-QLGLSTAIVEPKY-WGG 39 M+ +D++V+G+G G A RAA QLG IVE + GG Sbjct: 1 MSDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGG 41 >1ZOV-A nrPDB Length = 386 Score = 46.8 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 14/32 (43%), Positives = 21/32 (65%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 TH+DV+V+GAG G A A+ G+ T +V+ Sbjct: 2 THFDVIVVGAGSMGMAAGYYLAKQGVKTLLVD 33 Score = 28.7 bits (63), Expect = 5.2, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 18/32 (56%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP 204 +I+ GAG++GM GY L GV +V+ Sbjct: 5 DVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFD 36 >5KXJ-A nrPDB Length = 557 Score = 46.8 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 59/374 (15%), Positives = 107/374 (28%), Gaps = 75/374 (20%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW--GGVCLNVGCIPSKALLRNAELVHIF 62 DV+++G+G G A+R A+ ++ G G I A+ + + Sbjct: 10 DVLIIGSGAAGLSLALRLAEKH-KVIVLSKGPVSEGSTFYAQGGI--AAVFDETDSIASH 66 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAG---VHFLMKKNKITEIHGYGTFADAN 119 +D G +R + + ++ N H ++ Sbjct: 67 VEDTLIAGAGICDRHAVEFVASNARTCVQWLIDQGVLFDTHVQPNGKESYHLTREGGHSH 126 Query: 120 TLLVDLNDGGTESVT--------------------FDNAIIATGSSTRLVPGTSLSANVV 159 ++ D + V + II S +PG Sbjct: 127 RRILHAADATGKEVETTLVSRAQNHPNIQVLERSNAVDLII---SDKMGLPGPRRVVGAW 183 Query: 160 TYEEQILSRELP--KSIIIAGAGAI-------------GMEFGYVLKNYGVDVTIVEFLP 204 + E KS+++A GA G + G V +EF Sbjct: 184 IWNRNKEWVETCHAKSVVLATGGASKVYQYTTNPDISSGDGIAMAWRA-GCRVANLEFNQ 242 Query: 205 -RALPNEDADVSKEI-EKQFKKLGVTILTAT------KVESIADGGSQVTVTVTKDGVAQ 256 + + + G + V+ + + V D + Sbjct: 243 FHPTALYHPQARNFLLTEALRGEGAYLKRPDGSRFMPDVDERGELAPRDIVARAIDHEMK 302 Query: 257 ELKAEKVLQAIGFAPN--------VEGYGLDKAGVALTDR------------KAIGVDDY 296 +L A+ + I P+ + L G+ LT + VDDY Sbjct: 303 QLGADCMFLDISHKPDDFVRQHFPMIYAKLLDLGMDLTKEPIPVVPAAHYTCGGVVVDDY 362 Query: 297 MRTNVGHIYAIGDV 310 RT+V +YAIG+V Sbjct: 363 GRTDVDGLYAIGEV 376 >3K30-A nrPDB Length = 690 Score = 45.7 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 65/343 (18%), Positives = 104/343 (30%), Gaps = 87/343 (25%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY-WGGVCLNVGCIPSKALLRNAELVHIFTK 64 V+V+GAGP G AA G + E GG T+ Sbjct: 394 VLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGG---------------------RVTQ 432 Query: 65 DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVD 124 ++ G+S +V E R A + L + Sbjct: 433 ESALPGLSA------------WGRVKEYREAVLAEL---PNVEIYR-----------ESP 466 Query: 125 LNDGGTESVTFDNAIIATGS----------STRLVPGTSLSANVVTYEEQILSRELPKSI 174 + F++ I ATG+ T +P V+ ++ R Sbjct: 467 MTGDDIVEFGFEHVITATGATWRTDGVARFHTTALPIAE-GMQVLGPDDLFAGRLPDGKK 525 Query: 175 IIAG-------AGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADV-SKEIEKQFKKLG 226 ++ G + +L G +V+IV + + I+++ + G Sbjct: 526 VVVYDDDHYYLGGVV----AELLAQKGYEVSIVTPGAQVSSWTNNTFEVNRIQRRLIENG 581 Query: 227 VTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALT 286 V +T V ++ GG V T + +EL+ + V+ P E LD VA Sbjct: 582 VARVTDHAVVAVGAGGVTVRDTYAS--IERELECDAVVMVTARLPR-EELYLDL--VARR 636 Query: 287 DRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAE 329 D I +V I GD A G AAE Sbjct: 637 DAGEIA-------SVRGI---GDAWA-PGTIAAAVWSGRRAAE 668 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 41/115 (35%), Gaps = 3/115 (2%) Query: 163 EQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQF 222 E+I ++E +++ GAG G+E L G DV + E + + + Sbjct: 383 ERIRAKESDARVLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGGRVTQESALPGLSAW 442 Query: 223 KKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYG 277 + V + + + +T D + E E V+ A G +G Sbjct: 443 GR--VKEYREAVLAELPNVEIYRESPMTGDDIV-EFGFEHVITATGATWRTDGVA 494 >3T14-A nrPDB Length = 437 Score = 45.7 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 64/332 (19%), Positives = 99/332 (29%), Gaps = 84/332 (25%) Query: 6 VVVLGAGPGGYVAA---IRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 62 VV+LGAG GG AA A G ++ +A F Sbjct: 7 VVILGAGTGGMPAAYEMKEALGSGHEVTLI----------------------SANDYFQF 44 Query: 63 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLL 122 G+ + D + +++ I I DA Sbjct: 45 VPSNPWVGVGWKERDDIAFP--------------IRHYVERKGIHFIAQSAEQIDAEAQN 90 Query: 123 VDLNDGGTESVTFDNAIIATGSS------TRLVPGTSLSANVVTYEEQILSRELPKSII- 175 + L DG T V +D +IATG P ++ T + + ++++ Sbjct: 91 ITLADGNT--VHYDYLMIATGPKLAFENVPGSDPHEGPVQSIATVDHAERAFAEYQALLR 148 Query: 176 -----IAGA--GAI--------GMEFGYVLKNYGV-----DVTIVEFLPRALP---NEDA 212 + GA GA M LK G+ T + P Sbjct: 149 EPGPIVIGAMAGASCFGPAYEYAMIVASDLKKRGMRDKIPSFTFITSEPYIGHLGIQGVG 208 Query: 213 DVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQEL----KAEKVLQAIG 268 D + K K+ G+ T KV + D VT K +E+ K ++ A Sbjct: 209 DSKGILTKGLKEEGIEAYTNCKVTKVEDNKMYVTQVDEKGETIKEMVLPVKFGMMIPAFK 268 Query: 269 FAPNVEGYGLDKAGVA--LTDRKAIGVDDYMR 298 P V AGV + VD++ R Sbjct: 269 GVPAV-------AGVEGLCNPGGFVLVDEHQR 293 >1Y56-A nrPDB Length = 493 Score = 45.3 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 36/247 (14%), Positives = 74/247 (29%), Gaps = 38/247 (15%) Query: 67 KAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIH--GYGTFADANTLLVD 124 + G G + GI + K + V + + +N + G F LV Sbjct: 137 EERGWLGGDMWLKGIKQEGFNKDSRKVVEELVGKLNENTKIYLETSALGVFDKGEYFLVP 196 Query: 125 LNDG-GTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIG 183 + G + ++ATG+ + + ++P Sbjct: 197 VVRGDKLIEILAKRVVLATGA--------------IDSTMLFENNDMPG----VFRRDFA 238 Query: 184 MEFGYVLK-NYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGG 242 +E V + G V + + E+ ++ ++ G+ + V+ + Sbjct: 239 LEVMNVWEVAPGRKVAV-----------TGSKADEVIQELERWGIDYVHIPNVKRVEGNE 287 Query: 243 SQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGV-DDYMRTNV 301 V + E K + ++ A G P++ + V D+Y R Sbjct: 288 KVERVIDMNN---HEYKVDALIFADGRRPDINPITQAGGKLRFRRGYYSPVLDEYHRIK- 343 Query: 302 GHIYAIG 308 IY G Sbjct: 344 DGIYVAG 350 >3BHF-A nrPDB Length = 390 Score = 44.9 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 14/33 (42%), Positives = 22/33 (66%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP 34 TH+DV+V+GAG G A + A+ G+ T +V+ Sbjct: 3 THFDVIVVGAGSMGMAAGYQLAKQGVKTLLVDA 35 Score = 27.9 bits (61), Expect = 9.2, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 18/32 (56%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP 204 +I+ GAG++GM GY L GV +V+ Sbjct: 6 DVIVVGAGSMGMAAGYQLAKQGVKTLLVDAFD 37 >2UZZ-A nrPDB Length = 372 Score = 44.5 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 18/36 (50%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW 37 YD++++G+G G A A + GL+ + + Sbjct: 1 MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMP 36 >3KVE-A nrPDB Length = 486 Score = 44.5 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 20/35 (57%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPR 205 PK +++ GAG G+ YVL G VT++E R Sbjct: 33 PKHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASER 67 Score = 38.3 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 48/290 (16%), Positives = 84/290 (28%), Gaps = 59/290 (20%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG----VCLNVGCIPSKALLRN------ 55 VVV+GAG G AA A G ++E G N SK Sbjct: 36 VVVVGAGMSGLSAAYVLAGAGHKVTVLEASERAGGRVRTHRN-----SKEGWYANLGPMR 90 Query: 56 -AELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGT 114 E I + + FG++ K RV V+ G Sbjct: 91 IPEKHRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVGEVN-----------KDPGL 139 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTS----LSANVVTYEEQILSRE- 169 + G + GS+ + + T+ L+ ++ L +E Sbjct: 140 LKYPVKPSEEGKSAGQLYEE------SLGSAVKDLKRTNCSYILNKYDTYSTKEYLIKEG 193 Query: 170 --LPKSIIIAG------AGAIGMEFGYVLKNYGVDVTIVE---FLPRALPNEDADVSKEI 218 P ++ + G +G + +++ D I + D Sbjct: 194 NLSPGAVDMIGDLLNEDSGY----YVSFIESLKHD-DIFAYEKRFDEIVGGMDQ----LP 244 Query: 219 EKQFKKLGVTILTATKVESIADGGSQVTVTV-TKDGVAQELKAEKVLQAI 267 ++ + + +V I +QVTVT T + A+ V+ Sbjct: 245 TSMYRAIEEKVKFNARVIKIQQNANQVTVTYQTPEKDTSSNTADYVIVCT 294 >6A37-A nrPDB Length = 552 Score = 44.5 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 29/218 (13%), Positives = 61/218 (27%), Gaps = 26/218 (11%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQ-LGLSTAIVEP-KYWGGVCLNVGCIPSKALLRN-AEL 58 +D +++GAG GG + + L + GG Sbjct: 25 MDFDAIIIGAGFGGLYSLKKLRDDFNLKVRAFDRATEVGGT----------WFWNQYPGA 74 Query: 59 VHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKK----NKITEIHG-YG 113 + + E+ + I R +A + + K I G Sbjct: 75 LSDSETHLYCYSWDKELLQEMEI--KRKYISQPDVLAYLKRVADKHDLRKDIQFETGIRS 132 Query: 114 TFADANTLLVDLNDGGTESVTFDNAIIATG--SSTR--LVPGTSLSANVV--TYEEQILS 167 + D ++ E T I A G ++ + G + T Sbjct: 133 AYFDEENSFWNVTTENDEKFTARFLITALGLLAAPNLPKIKGIETFKGELHHTSRWPKDV 192 Query: 168 RELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPR 205 K + + G G+ G++ + + +T+ + + Sbjct: 193 TFSGKRVGVIGTGSTGVQVITAIASQVKHLTVFQRSAQ 230 >1REO-A nrPDB Length = 486 Score = 44.1 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 20/35 (57%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPR 205 PK +++ GAG G+ YVL G VT++E R Sbjct: 33 PKHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASER 67 >3ATQ-A nrPDB Length = 453 Score = 43.7 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 21/35 (60%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW 37 YDV+++G G G AA + ++ GL +V+ K W Sbjct: 6 KYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPW 40 Score = 38.3 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 38/98 (38%), Gaps = 4/98 (4%) Query: 167 SRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLG 226 +EL ++I G G G Y L G+ + +V+ P + + F KLG Sbjct: 2 MKELKYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRIGDKPCGDAVSKAHFDKLG 61 Query: 227 VTILTATKVESIADG----GSQVTVTVTKDGVAQELKA 260 + ++E+ +G + T +G EL A Sbjct: 62 MPYPKGEELENKINGIKLYSPDMQTVWTVNGEGFELNA 99 >4DGK-A nrPDB Length = 501 Score = 43.4 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 47/271 (17%), Positives = 94/271 (34%), Gaps = 35/271 (12%) Query: 8 VLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGGVCLNVGCIPSKALLRNA---------- 56 V+GAG GG AIR G+ ++E GG V Sbjct: 6 VIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGR-AYVYEDQGFTFDAGPTVITDPSAIE 64 Query: 57 ELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKV-AEGRVAGVHFLMKKNKITEIHGYGTF 115 EL + K K + VT Y + ++ + + + +++ ++ GY F Sbjct: 65 ELFALAGKQLKEYVELLPVTPFYRLCWESGKVFNYDNDQTRLEAQIQQFNPRDVEGYRQF 124 Query: 116 ADANTLLVD---LNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTY-EEQILSRELP 171 D + + L G ++F + + A +L S+ + V +Y E++ L + Sbjct: 125 LDYSRAVFKEGYLKLGTVPFLSFRDMLRAAPQLAKLQAWRSVYSKVASYIEDEHLRQAFS 184 Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDV--TIVEFLPR-----ALPNEDADVSKEIEKQFKK 224 ++ G + T++ L R + + + K F+ Sbjct: 185 FHSLLVGG-----------NPFATSSIYTLIHALEREWGVWFPRGGTGALVQGMIKLFQD 233 Query: 225 LGVTILTATKVESIADGGSQVTVTVTKDGVA 255 LG ++ +V + G+++ +DG Sbjct: 234 LGGEVVLNARVSHMETTGNKIEAVHLEDGRR 264 Score = 31.8 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 16/35 (45%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 K + GAG G+ L+ G+ V ++E + Sbjct: 2 KPTTVIGAGFGGLALAIRLQAAGIPVLLLEQRDKP 36 >4Y4M-A nrPDB Length = 290 Score = 43.0 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 17/31 (54%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK 35 DVV++GAGP G A A+ G ++E Sbjct: 61 DVVIVGAGPSGLTCARYLAKEGFKVVVLERH 91 Score = 34.9 bits (79), Expect = 0.079, Method: Composition-based stats. Identities = 24/149 (16%), Positives = 46/149 (30%), Gaps = 34/149 (22%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFL-----------------------PRALPN 209 ++I GAG G+ L G V ++E L Sbjct: 61 DVVIVGAGPSGLTCARYLAKEGFKVVVLERHLAFGGGTWGGGMGFPYIVVEEPADELLRE 120 Query: 210 EDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGF 269 + + + V + V ++ G +T V +D + +E V+ Sbjct: 121 VGIKLIDMGDGYYVADSVEVPAKLAVAAMDAGAKILTGIVVEDLILREDGVAGVVI---- 176 Query: 270 APNVEGYGLDKAGVALTD---RKAIGVDD 295 Y +++AG+ + R + VD Sbjct: 177 ----NSYAIERAGLHIDPLTIRSKVVVDA 201 >2VOU-A nrPDB Length = 397 Score = 43.0 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 25/60 (41%), Gaps = 2/60 (3%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVS--KEIEKQFKKLGVTI 229 I + G G+ +L++ GVDV + E P+ L + E+ + GV + Sbjct: 6 DRIAVVGGSISGLTAALMLRDAGVDVDVYERSPQPLSGFGTGIVVQPELVHYLLEQGVEL 65 >1F8S-A nrPDB Length = 498 Score = 43.0 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 15/36 (41%), Positives = 20/36 (55%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 PK ++I GAG G+ YVL G VT++E R Sbjct: 33 PKHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERP 68 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 40/283 (14%), Positives = 82/283 (28%), Gaps = 45/283 (15%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGG---VCLNVGCIPSKALLR---NAEL 58 VV++GAG G AA A G ++E + GG N +A Sbjct: 36 VVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRTYRN-----EEAGWYANLGPMR 90 Query: 59 VHIFTKDAKAFGISGEVTFD-YGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFAD 117 + + + + ++ + + D + + V + K + + + A Sbjct: 91 LPEKHRIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVGEVKKDPGLLKYPVKPSEAG 150 Query: 118 ANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRE---LPKSI 174 + + G T S L+ ++ L +E P ++ Sbjct: 151 KSAGQLYEESLGKVVEELKR----TNCSYI------LNKYDTYSTKEYLIKEGDLSPGAV 200 Query: 175 IIAG------AGAIGMEFGYVLKNYGVDVTIVE---FLPRALPNEDADVSKEIEKQFKKL 225 + G +G + +++ D I + D + K Sbjct: 201 DMIGDLLNEDSGY----YVSFIESLKHD-DIFAYEKRFDEIVDGMDKLPTAMYRDIQDK- 254 Query: 226 GVTILTATKVESIADGGSQVTVTV-TKDGVAQELKAEKVLQAI 267 + +V I +VTV T + A+ V+ Sbjct: 255 ---VHFNAQVIKIQQNDQKVTVVYETLSKETPSVTADYVIVCT 294 >2JB2-A nrPDB Length = 489 Score = 43.0 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 18/37 (48%), Gaps = 1/37 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGG 39 + VVVLG GP G +A + G ++E GG Sbjct: 12 HSVVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGG 48 Score = 32.2 bits (72), Expect = 0.50, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 18/34 (52%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 S+++ G G G+ + L+ G VT++E R Sbjct: 13 SVVVLGGGPAGLCSAFELQKAGYKVTVLEARTRP 46 Score = 31.8 bits (71), Expect = 0.69, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 18/40 (45%) Query: 228 TILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAI 267 I+ +V S+ + VTV T G + + A+ + I Sbjct: 253 NIVFGAEVTSMKNVSEGVTVEYTAGGSKKSITADYAICTI 292 >6JDK-A nrPDB Length = 544 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 38/234 (16%), Positives = 76/234 (32%), Gaps = 14/234 (5%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 +D +++GAG G R Q G + E G C P A + + ++ F+ Sbjct: 18 FDALIVGAGFNGIYQLHRLRQEGFKVRLFEAGADMGGIWYWNCYPG-ARVDSHIPIYEFS 76 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV 123 + + F R + ++ L + + F D Sbjct: 77 IEELWRDWNWTERFPAWDELRRYFHYVDKKLD----LSRDIRFGMRVSAAEF-DEARDQW 131 Query: 124 DLNDGGTESVTFDNAIIATG-SSTRLVPGTSLSANVV--TYEEQILSRE----LPKSIII 176 + V I+ TG +S +P + ++ + +E K + + Sbjct: 132 VIRTTDGTVVRARFFILCTGFASKPYIPNYKGLESFAGESFHTGLWPQEGASFTGKRVGV 191 Query: 177 AGAGAIGMEFGYVLKNYGVDVTIVEFLPRA-LPNEDADVSKEIEKQFKKLGVTI 229 G GA G++ +T+ + P LP + + E +++ K I Sbjct: 192 VGTGASGVQVVQEASKDAAHLTVFQRTPILALPMQQRKLDVETQQRMKADYPEI 245 >3RHA-A nrPDB Length = 482 Score = 42.6 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGG 39 DVV++GAGP G AA + GLS A++E GG Sbjct: 9 DVVIVGAGPSGLTAARELKKAGLSVAVLEARDRVGG 44 Score = 40.3 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 40/98 (40%), Gaps = 5/98 (5%) Query: 167 SRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLG 226 + L + ++I GAG G+ LK G+ V ++E R + I+ ++G Sbjct: 3 MQNLDRDVVIVGAGPSGLTAARELKKAGLSVAVLEARDRVGGR---TWTDTIDGAMLEIG 59 Query: 227 VTILTA--TKVESIADGGSQVTVTVTKDGVAQELKAEK 262 ++ T + + D + +DG + + A+ Sbjct: 60 GQWVSPDQTVLMELLDELGLKMYSRYRDGESVYIGADG 97 >1I8T-A nrPDB Length = 367 Score = 42.2 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 26/67 (38%), Gaps = 1/67 (1%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY-WGGVCLNVGCIPSKALLRNAELVHIF 62 YD +++G+G G V A +L ++E + GG C + A + H Sbjct: 2 YDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTEDCEGIQIHKYGAHIFHTN 61 Query: 63 TKDAKAF 69 K + Sbjct: 62 DKYIWDY 68 Score = 28.3 bits (62), Expect = 6.8, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 12/32 (37%) Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 II G+G G LK V ++E Sbjct: 5 IIVGSGLFGAVCANELKKLNKKVLVIEKRNHI 36 >4B68-A nrPDB Length = 501 Score = 42.2 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 15/107 (14%), Positives = 36/107 (33%), Gaps = 15/107 (14%) Query: 124 DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYE-------EQILSRELPKSIII 176 ++ G + +IA G + ++ G ++ + + P +I + Sbjct: 192 NVETGEISARRTRKVVIAIGGTAKMPSGLPQDPRIIHSSKYCTTLPALLKDKSKPYNIAV 251 Query: 177 AGAGAIGMEFGYVLKNY-----GVDVTIVEFLPRALPNEDADVSKEI 218 G+G E + + T++ P++D+ EI Sbjct: 252 LGSGQSAAE---IFHDLQKRYPNSRTTLIMRDSAMRPSDDSPFVNEI 295 >2GMH-A nrPDB Length = 584 Score = 42.2 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 12/51 (23%) Query: 5 DVVVLGAGPGGYVAAIR----AAQLG--LSTAIVEP------KYWGGVCLN 43 DVV++GAGP G AA R AAQ L +VE G CL+ Sbjct: 37 DVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHTLSGACLD 87 >3NIX-A nrPDB Length = 421 Score = 41.8 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 15/33 (45%), Positives = 20/33 (60%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW 37 DV+V+GAGP G VAA + G IVE + + Sbjct: 7 DVLVIGAGPAGTVAASLVNKSGFKVKIVEKQKF 39 Score = 29.1 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 24/80 (30%), Gaps = 15/80 (18%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVE------------FLPRALPNEDADVSKEIEK 220 +++ GAG G ++ G V IVE LPR + + D Sbjct: 7 DVLVIGAGPAGTVAASLVNKSGFKVKIVEKQKFPRFVIGESLLPRCMEHLDE---AGFLD 63 Query: 221 QFKKLGVTILTATKVESIAD 240 K G K + Sbjct: 64 AVKAQGFQQKFGAKFVRGKE 83 >4Y4N-A nrPDB Length = 286 Score = 41.8 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 16/31 (51%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK 35 DV ++G GP G AA A+ G ++E Sbjct: 54 DVAIVGGGPSGLTAARYIAKEGYKVVVLERH 84 Score = 30.6 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 24/140 (17%), Positives = 44/140 (31%), Gaps = 33/140 (23%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFL-------------------PRALPNEDAD 213 + I G G G+ + G V ++E + Sbjct: 54 DVAIVGGGPSGLTAARYIAKEGYKVVVLERHLAFGGGTWGGGMGFPYIVVEEPADEILRE 113 Query: 214 VSKEIEKQ------FKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAI 267 V ++EK + V + V +I G +T V +D V +E + V+ Sbjct: 114 VGVKLEKVEGEDGLYTADSVEVPAKLAVGAIDAGAKVLTGIVVEDLVLRENRVAGVVI-- 171 Query: 268 GFAPNVEGYGLDKAGVALTD 287 Y ++KAG+ + Sbjct: 172 ------NSYAIEKAGLHIDP 185 >2BXR-A nrPDB Length = 527 Score = 41.8 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGG 39 +DVVV+G G G AA + G+S ++E GG Sbjct: 14 FDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGG 50 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 17/34 (50%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 +++ G G G+ +L YGV V ++E R Sbjct: 15 DVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRV 48 >1O5W-A nrPDB Length = 534 Score = 41.4 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 20/37 (54%), Gaps = 1/37 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGG 39 +DVVV+G G G AA ++ ++ ++E GG Sbjct: 22 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGG 58 Score = 36.4 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 17/34 (50%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 +++ G G G+ +L Y ++V ++E R Sbjct: 23 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRV 56 >3MJ4-A nrPDB Length = 397 Score = 41.4 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 10/72 (13%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-YWGGV---CLNVGCIPSKALLR--NAE 57 +D +++GAG G V A R A G IV+ + + GG C + + L+ Sbjct: 30 FDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNAYDCYDDAGV----LIHPYGPH 85 Query: 58 LVHIFTKDAKAF 69 + H +KD + Sbjct: 86 IFHTNSKDVFEY 97 Score = 31.4 bits (70), Expect = 0.82, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 14/32 (43%) Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 +I GAG G L + G V IV+ P Sbjct: 33 LIVGAGFAGSVLAERLASSGQRVLIVDRRPHI 64 >2GAG-A nrPDB Length = 965 Score = 41.0 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 52/287 (18%), Positives = 91/287 (31%), Gaps = 45/287 (15%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIV-EPKYWGGVCLNVGCIPSKALLRNAELVHI 61 H DV+V+GAGP G AA A++ G ++ E GG L+ E + Sbjct: 128 HTDVLVVGAGPAGLAAAREASRSGARVMLLDERAEAGGTLLD----------TAGEQIDG 177 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTL 121 A ++ E+ + + V A ++ + G + Sbjct: 178 MDSSAWIEQVTSELAEAEETTHLQRTTVFGSYDANYLIAAQRRTVHLDGPSGPGVSRERI 237 Query: 122 LVDLNDGGTESVTFDNAIIATGSSTRLV-------PGTSLSANVVTYEEQILSRELPKSI 174 + ++ATG+ R + PG L+ V +Y + R I Sbjct: 238 W---------HIRAKQVVLATGAHERPIVFENNDRPGIMLAGAVRSYLNRYGVRA-GARI 287 Query: 175 IIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATK 234 +A E L G V +++ Q GV +++ + Sbjct: 288 AVATTNDSAYELVRELAATGGVVAVIDARSS---------ISAAAAQAVADGVQVISGSV 338 Query: 235 VESIADGGSQ-----VTVTVTKD---GVAQELKAEKVLQAIGFAPNV 273 V + V + + G Q +A+ + A GF P V Sbjct: 339 VVDTEADENGELSAIVVAELDEARELGGTQRFEADVLAVAGGFNPVV 385 >5EQD-A nrPDB Length = 400 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 2/39 (5%) Query: 3 HYDVVVLGAGPGGYVAAIRAA-QLGLSTAIVEPK-YWGG 39 ++D+ V+G+G G A RAA QLG ++E + + GG Sbjct: 4 NFDLFVVGSGFFGLTIAERAATQLGKRVLVIERRPHIGG 42 Score = 31.8 bits (71), Expect = 0.59, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 13/35 (37%), Gaps = 1/35 (2%) Query: 173 SIIIAGAGAIGMEFGY-VLKNYGVDVTIVEFLPRA 206 + + G+G G+ G V ++E P Sbjct: 6 DLFVVGSGFFGLTIAERAATQLGKRVLVIERRPHI 40 >6CR0-A nrPDB Length = 440 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 31/90 (34%), Gaps = 10/90 (11%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGGV--CLNVGCIPSKAL-----L 53 YD +V+GAG G VAA + G S I+E GG +N P + Sbjct: 7 KIYDAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRTHVVNFLGRPVEIGGAGVHW 66 Query: 54 RNAELVHIFTKDAKAFGISGEVTFDYGIAY 83 + + FG D AY Sbjct: 67 CQPHVFAEMQRY--GFGFKEAPLADLDKAY 94 Score = 31.8 bits (71), Expect = 0.74, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 14/34 (41%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 I+ GAG G+ L G V I+E R Sbjct: 10 DAIVVGAGFSGLVAARELSAQGRSVLIIEARHRL 43 >3ABT-A nrPDB Length = 662 Score = 40.7 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 21/35 (60%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 +II G+G G+ L+++G+DVT++E R Sbjct: 108 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 142 Score = 35.3 bits (80), Expect = 0.063, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%), Gaps = 1/35 (2%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGG 39 V+++G+G G AA + G+ ++E GG Sbjct: 110 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 144 >5L3D-A nrPDB Length = 852 Score = 40.3 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 21/35 (60%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 +II G+G G+ L+++G+DVT++E R Sbjct: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 Score = 34.9 bits (79), Expect = 0.080, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%), Gaps = 1/35 (2%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGG 39 V+++G+G G AA + G+ ++E GG Sbjct: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 >1QO8-A nrPDB Length = 566 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 46/113 (40%), Gaps = 9/113 (7%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKD 65 V+V+GAG G+ A++ A + G + +V+ + G +++ + + TK Sbjct: 124 VLVVGAGSAGFNASLAAKKAGANVILVDKAPFSG---------GNSMISAGGMNAVGTKQ 174 Query: 66 AKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADA 118 A G+ +V + A R+ + ++ + + + + G D Sbjct: 175 QTAHGVEDKVEWFIEDAMKGGRQQNDIKLVTILAEQSADGVQWLESLGANLDD 227 >1KNR-A nrPDB Length = 540 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 58/377 (15%), Positives = 102/377 (27%), Gaps = 81/377 (21%) Query: 5 DVVVLGAGPGGYVAAIRAA-QLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFT 63 DV+++G+G G A+R A Q + P G G I A+ + + Sbjct: 10 DVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEGSTFYAQGGI--AAVFDETDSIDSHV 67 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAG---VHFLMKKNKITEIHGYGTFADANT 120 +D G +R + + ++ N H ++ Sbjct: 68 EDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVLFDTHIQPNGEESYHLTREGGHSHR 127 Query: 121 LLVDLNDGGTESVTF---------------------DNAIIATGSSTRLVPGTSLSANVV 159 ++ D V D + S +PGT Sbjct: 128 RILHAADATGREVETTLVSKALNHPNIRVLERTNAVDLIV----SDKIGLPGTRRVVGAW 183 Query: 160 TYEEQILSRELPKSIIIA----GAGAI-----------GMEFGYVLKNYGVDVTIVEFLP 204 + + E + + GA + G + G V +EF Sbjct: 184 VWNRNKETVETCHAKAVVLATGGASKVYQYTTNPDISSGDGIAMAWRA-GCRVANLEFNQ 242 Query: 205 -RALPNEDADVSKEI-EKQFKKLGVTILTATKVESIADGGSQ------VTVTVTKDGVAQ 256 + + + G + + D + V D + Sbjct: 243 FHPTALYHPQARNFLLTEALRGEGAYLKRPDGTRFMPDFDERGELAPRDIVARAIDHEMK 302 Query: 257 ELKAEKVLQAIGFAP-----------NVEGYGLDKAGVALTDR------------KAIGV 293 L A+ + I P + GL G+ LT + V Sbjct: 303 RLGADCMFLDISHKPADFIRQHFPMIYEKLLGL---GIDLTQEPVPIVPAAHYTCGGVMV 359 Query: 294 DDYMRTNVGHIYAIGDV 310 DD+ RT+V +YAIG+V Sbjct: 360 DDHGRTDVEGLYAIGEV 376 >4C3X-A nrPDB Length = 530 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-YWGGVCLNVG 45 DV+V+G+G G A AA GL+T ++E +GG G Sbjct: 29 DVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSG 70 >2BRY-A nrPDB Length = 497 Score = 39.9 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 13/29 (44%), Positives = 18/29 (62%) Query: 7 VVLGAGPGGYVAAIRAAQLGLSTAIVEPK 35 +V+GAGP G AA+ A LG +VE + Sbjct: 96 LVVGAGPCGLRAAVELALLGARVVLVEKR 124 Score = 30.6 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 46/176 (26%), Gaps = 47/176 (26%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFL--------PRALPNEDADVSKEIEKQF-- 222 ++ GAG G+ L G V +VE P D+ K+F Sbjct: 94 KCLVVGAGPCGLRAAVELALLGARVVLVEKRIKFSRHNVLHLWPFTIHDLRALGAKKFYG 153 Query: 223 -----------------------KKLGVTILTATKVESI-----ADGGSQVTVTVTKDGV 254 LGV I K + G + + Sbjct: 154 RFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVKFTGLQPPPRKGSGWRAQLQPNPPAQ 213 Query: 255 AQELKAEKVLQAIGFAPNVEGY------GLDKAGVALTDRKAIGVDDYMRTNVGHI 304 + + ++ A G EG+ G G+ V++ T V I Sbjct: 214 LASYEFDVLISAAGGKFVPEGFTIREMRGKLAIGITANFVNGRTVEE---TQVPEI 266 >3WE0-A nrPDB Length = 580 Score = 39.9 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 14/34 (41%), Positives = 18/34 (52%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG 39 V ++GAG G VAA +LGL + E GG Sbjct: 68 VAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGG 101 >4TXK-A nrPDB Length = 615 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 13/29 (44%), Positives = 18/29 (62%) Query: 7 VVLGAGPGGYVAAIRAAQLGLSTAIVEPK 35 +V+GAGP G AA+ A LG +VE + Sbjct: 88 LVVGAGPCGLRAAVELALLGARVVLVEKR 116 Score = 30.6 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 46/176 (26%), Gaps = 47/176 (26%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFL--------PRALPNEDADVSKEIEKQF-- 222 ++ GAG G+ L G V +VE P D+ K+F Sbjct: 86 KCLVVGAGPCGLRAAVELALLGARVVLVEKRIKFSRHNVLHLWPFTIHDLRALGAKKFYG 145 Query: 223 -----------------------KKLGVTILTATKVESI-----ADGGSQVTVTVTKDGV 254 LGV I K + G + + Sbjct: 146 RFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVKFTGLQPPPRKGSGWRAQLQPNPPAQ 205 Query: 255 AQELKAEKVLQAIGFAPNVEGY------GLDKAGVALTDRKAIGVDDYMRTNVGHI 304 + + ++ A G EG+ G G+ V++ T V I Sbjct: 206 LASYEFDVLISAAGGKFVPEGFTIREMRGKLAIGITANFVNGRTVEE---TQVPEI 258 >6HNS-A nrPDB Length = 454 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 40/224 (17%), Positives = 70/224 (31%), Gaps = 39/224 (17%) Query: 6 VVVLGAGPGGYV---AAIRAAQLGL---STAIVEPKY-WGG-------VCLNVGCIPSKA 51 V ++GAGP G A AA G E + WGG ++ P Sbjct: 5 VAIIGAGPCGLAQLRAFQSAAAKGAAIPELVCFEKQSDWGGMWNYTWRTGVDEHGEP--- 61 Query: 52 LLRNAELVHIFTKDA------------KAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHF 99 + + ++++ + FG + +D + E AGV Sbjct: 62 -VHGSMYRYLWSNGPKECLEFADYTFDEHFGRPIGSYPPREVLWDYIKGRVEK--AGVRD 118 Query: 100 LMKKNKITEIHGYGTFADANTLLV-DLNDGGTESVTFDNAIIATG--SSTR--LVPGTSL 154 ++ N Y + ++ V D ++ + TFD + A G S+ G Sbjct: 119 YIRFNTAVRQVSYDETSGLFSVTVQDHSNNRVYTETFDYVVNACGHFSTPNTPYFEGFER 178 Query: 155 SANVVTYEEQI--LSRELPKSIIIAGAGAIGMEFGYVLKNYGVD 196 V + K I++ G+ + G YG Sbjct: 179 FGGRVLHAHDFRDALEFKDKDILVVGSSYSAEDIGSQCYKYGAR 222 Score = 29.9 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 29/79 (36%), Gaps = 9/79 (11%) Query: 216 KEIEKQFKKLGVT--ILTATKVESI----ADGGSQVTVTVTKDGVAQELKAEKVLQAIGF 269 I+ + +K GV I T V + G VTV + + V+ A G Sbjct: 105 DYIKGRVEKAGVRDYIRFNTAVRQVSYDETSGLFSVTVQDHSNNRVYTETFDYVVNACGH 164 Query: 270 --APNVEGY-GLDKAGVAL 285 PN + G ++ G + Sbjct: 165 FSTPNTPYFEGFERFGGRV 183 >2VVL-G nrPDB Length = 495 Score = 39.1 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 32/93 (34%), Gaps = 10/93 (10%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGGV--CLNVGCIPSKAL------LRN 55 DV+V+G G G A G T ++E GG N+ P + Sbjct: 41 DVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGRSWSSNIDGYP-YEMGGTWVHWHQ 99 Query: 56 AELVHIFTKDAKAFGISGEVTFDYGIAYDRSRK 88 + + T+ +S F G+ + + R Sbjct: 100 SHVWREITRYKMHNALSPSFNFSRGVNHFQLRT 132 Score = 33.3 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 167 SRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 ++ P +I+ G G G+ L G ++E R Sbjct: 35 DKDGPWDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRI 74 >1F14-A nrPDB Length = 310 Score = 38.7 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 34/98 (34%), Gaps = 3/98 (3%) Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTI 229 + K + + G G +G V G V +V+ L + + + K KK Sbjct: 14 IVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK---KF 70 Query: 230 LTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAI 267 K + T+ + D + + V++AI Sbjct: 71 AENPKAGDECVEKTLSTIATSTDAASVVHSTDLVVEAI 108 >3NK2-X nrPDB Length = 431 Score = 38.7 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 16/37 (43%), Gaps = 1/37 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK-YWGG 39 YD +V+G G G AA G ++E GG Sbjct: 2 YDAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGG 38 Score = 32.6 bits (73), Expect = 0.42, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 15/34 (44%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 I+ G G G++ L N G V ++E R Sbjct: 3 DAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERL 36 >2VHY-A nrPDB Length = 377 Score = 38.3 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 39/113 (34%), Gaps = 15/113 (13%) Query: 125 LNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRE--------------- 169 L D GT S+ ++ A G+ L P + ++ + Sbjct: 107 LLDSGTTSIAYETVQTADGALPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGV 166 Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQF 222 P +++ GAG G + G VT+++ L DA+ I ++ Sbjct: 167 EPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRY 219 Score = 36.4 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 13/29 (44%), Positives = 19/29 (65%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 DVVV+GAG GY AA A +G + +++ Sbjct: 170 DVVVIGAGTAGYNAARIANGMGATVTVLD 198 >4A6N-B nrPDB Length = 398 Score = 38.3 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 34/89 (38%), Gaps = 9/89 (10%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVE----FLPRALPNEDADVSKEIEKQFKKLGV 227 K++ I G G +G+ +L+ G+DV++ E R ++ KK G+ Sbjct: 27 KNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREARIFGGTLDLHKGSGQEAMKKAGL 86 Query: 228 -----TILTATKVESIADGGSQVTVTVTK 251 + V + G+ ++ K Sbjct: 87 LQTYYDLALPMGVNIADEKGNILSTKNVK 115 Score = 34.1 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 18/41 (43%), Gaps = 6/41 (14%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP------KYWGGV 40 V ++G GP G A Q G+ ++ E + +GG Sbjct: 29 VAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREARIFGGT 69 >3IHG-A nrPDB Length = 535 Score = 38.3 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 20/31 (64%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK 35 DV+V+GAG GG A+ A+ G+ +VE + Sbjct: 7 DVLVVGAGLGGLSTAMFLARQGVRVLVVERR 37 Score = 34.5 bits (78), Expect = 0.094, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 16/32 (50%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP 204 +++ GAG G+ L GV V +VE P Sbjct: 7 DVLVVGAGLGGLSTAMFLARQGVRVLVVERRP 38 >4AP1-A nrPDB Length = 549 Score = 38.3 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 33/209 (15%), Positives = 65/209 (31%), Gaps = 14/209 (6%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61 T YDVVV+GAG G A R GL+ E VG + A Sbjct: 20 TSYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASG------VGGVWYWNRYPGARCDVE 73 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITE-IHGYGTFADANT 120 + +F E +++ Y ++ + I D Sbjct: 74 SIDYSYSFSPELEQEWNWSEKYATQPEILAYLEHVADRFDLRRDIRFDTRVTSAVLDEEG 133 Query: 121 LLVDLNDGGTESVTFDNAIIATG----SSTRLVPGTSLSANVVTYEEQILSRELP---KS 173 L + + V+ ++A G ++T G + + + + K Sbjct: 134 LRWTVRTDRGDEVSARFLVVAAGPLSNANTPAFDGLDRFTGDIVHTARWPHDGVDFTGKR 193 Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEF 202 + + G G+ G++ ++ + + + Sbjct: 194 VGVIGTGSSGIQSIPIIAEQAEQLFVFQR 222 >6C6P-A nrPDB Length = 458 Score = 38.3 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 16/29 (55%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEF 202 +II GAG +G VL G VT++E Sbjct: 10 VIIVGAGVLGSALAAVLSRDGRKVTVIER 38 >2XVH-A nrPDB Length = 464 Score = 38.3 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 42/224 (18%), Positives = 77/224 (34%), Gaps = 39/224 (17%) Query: 6 VVVLGAGPGGYVA--AIRAAQ-LGLST---AIVEPKY-WGGVCL---NVGCIPSKALLRN 55 + +LGAGP G A ++AQ G E + WGG G + + + Sbjct: 5 IAILGAGPSGMAQLRAFQSAQEKGAEIPELVCFEKQADWGGQWNYTWRTGLDENGEPVHS 64 Query: 56 AELVHIFTKDA------------KAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKK 103 + ++++ + FG + +D + E AGV ++ Sbjct: 65 SMYRYLWSNGPKECLEFADYTFDEHFGKPIASYPPREVLWDYIKGRVEK--AGVRKYIRF 122 Query: 104 NKITEIHGYGTF-ADANTLLVDLNDGGTESV---TFDNAIIATG--SSTRLVP---GTSL 154 N + F D+ T V + D T+++ FD + TG S+ VP G Sbjct: 123 NTAVR---HVEFNEDSQTFTVTVQDHTTDTIYSEEFDYVVCCTGHFSTP-YVPEFEGFEK 178 Query: 155 SANVVTYEEQI--LSRELPKSIIIAGAGAIGMEFGYVLKNYGVD 196 + + K++++ G+ + G YG Sbjct: 179 FGGRILHAHDFRDALEFKDKTVLLVGSSYSAEDIGSQCYKYGAK 222 >5CQF-A nrPDB Length = 443 Score = 38.3 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 40/240 (16%), Positives = 74/240 (30%), Gaps = 53/240 (22%) Query: 3 HYDVVVLGAGPGG--YVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIP--------SKAL 52 H D + +G GP G A A+ E G L++G + + L Sbjct: 13 HSDAICIGFGPAGIALACAFEDAR--------EASQPLGD-LSIGYLEAAPDTQWHRELL 63 Query: 53 LRNAELVHIFTKD------------AKAFGISGEVTFDYGIA------YDRSRKV--AEG 92 L ++ H +D + FD+G+ ++ S + Sbjct: 64 LAGTDINHHVFRDLVTPRNPRSRFSFAMYLKDQGRMFDFGLLGRPASRHEWSDYLGWVSR 123 Query: 93 RVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGT 152 +V G +TEI + V G N ++++GS+ R+ Sbjct: 124 QVDGHTRF--DTPVTEIDPVIRNGRLQEVRVRTPQGS---FATRNLVLSSGSAPRIPQAF 178 Query: 153 SLSANVVTYEEQILS-------RELPKSIIIAGAGAIGMEFGYVLKNY--GVDVTIVEFL 203 + ++LPK ++ G+G E L + ++V V Sbjct: 179 EALLGPTLFHTSRFLTRLQAFGKQLPKRWLVLGSGQSASESVLELVSRDPAIEVHSVHRC 238 >1C0L-A nrPDB Length = 363 Score = 38.3 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 16/31 (51%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEF 202 K +++ G+G IG+ +L G V I+ Sbjct: 7 KRVVVLGSGVIGLSSALILARKGYSVHILAR 37 >6BRD-A nrPDB Length = 476 Score = 38.0 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 18/33 (54%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY 36 +DV+V+G GP G + A G+ ++E + Sbjct: 2 FDVIVVGGGPTGLMLAGELRLHGVRVLVLEKET 34 Score = 30.6 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 16/29 (55%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVE 201 +I+ G G G+ L+ +GV V ++E Sbjct: 3 DVIVVGGGPTGLMLAGELRLHGVRVLVLE 31 >4MOP-A nrPDB Length = 633 Score = 38.0 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 16/35 (45%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW 37 YDVV++G+GP G A G A+ + Sbjct: 46 KYDVVIVGSGPIGCTYARELVGAGYKVAMFDIGEI 80 Score = 30.6 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 14/32 (43%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP 204 ++I G+G IG + L G V + + Sbjct: 48 DVVIVGSGPIGCTYARELVGAGYKVAMFDIGE 79 >2E5V-A nrPDB Length = 472 Score = 38.0 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 25/172 (14%), Positives = 48/172 (27%), Gaps = 36/172 (20%) Query: 8 VLGAGPGGYVAAIRAAQLGLSTAIVEPK--------YWGGVCLNVGCIPS---------- 49 ++G+G G A + + G ++ + GGV +VG S Sbjct: 4 IIGSGIAGLSAGVALRRAGKKVTLISKRIDGGSTPIAKGGVAASVGSDDSPELHAQDTIR 63 Query: 50 --------KALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLM 101 K + + +++G E + + R + G Sbjct: 64 VGDGLCDVKTVNYVTSEAKNVIETFESWGFEFEEDLRLEGGHTKRRVLHRTDETGREIFN 123 Query: 102 KKNKITEIHGYGTFADANTLLVDLNDGGTE---------SVTFDNAIIATGS 144 K+ G D + + + DG D ++ATG Sbjct: 124 FLLKLAREEGIPIIED-RLVEIRVKDGKVTGFVTEKRGLVEDVDKLVLATGG 174 Score = 30.3 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 14/28 (50%) Query: 176 IAGAGAIGMEFGYVLKNYGVDVTIVEFL 203 I G+G G+ G L+ G VT++ Sbjct: 4 IIGSGIAGLSAGVALRRAGKKVTLISKR 31 >3S61-A nrPDB Length = 463 Score = 38.0 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 40/293 (13%), Positives = 79/293 (26%), Gaps = 74/293 (25%) Query: 79 YGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNA 138 + ++ + + V + ++ ++ + ++ DG T Sbjct: 135 WVASHFQEQSRYGEEVLRIEPMLSAGQVEALR----------VISRNADGEELVRTTRAL 184 Query: 139 IIATGSSTRLVPGT-SLSANVVTYEEQILSRELPK---------SIIIAGAGAIGMEF-- 186 +++ G + R+ +L + + + K I I G G E Sbjct: 185 VVSPGGTPRIPQVFRALKGDGRVFHHSQYLEHMAKQPCSSGKPMKIAIIGGGQSAAEAFI 244 Query: 187 ----------------GYVLKNYGVD-----------VTIVEF-----LPRALPNE---- 210 LK ++ R L Sbjct: 245 DLNDSYPSVQADMILRASALKPADDSPFVNEVFAPKFTDLIYSREHAERERLLREYHNTN 304 Query: 211 ----DADVSKEIEKQFKKLGVT------ILTATKVESIADGGSQVTVTV--TKDGVAQEL 258 D D+ + I F + V+ T VE + + + G Sbjct: 305 YSVVDTDLIERIYGVFYRQKVSGIPRHAFRCMTTVERATATAQGIELALRDAGSGELSVE 364 Query: 259 KAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVG---HIYAIG 308 + V+ A G+ + L+ L D IG D ++T+ IYA G Sbjct: 365 TYDAVILATGYERQLHRQLLEPLAEYLGDH-EIGRDYRLQTDERCKVAIYAQG 416 Score = 29.1 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 30/97 (30%), Gaps = 2/97 (2%) Query: 48 PSKA-LLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKI 106 P L+ + E + + + + D + +V+G+ + Sbjct: 279 PKFTDLIYSREHAER-ERLLREYHNTNYSVVDTDLIERIYGVFYRQKVSGIPRHAFRCMT 337 Query: 107 TEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATG 143 T T L D G T+D I+ATG Sbjct: 338 TVERATATAQGIELALRDAGSGELSVETYDAVILATG 374 >3HDH-A nrPDB Length = 302 Score = 38.0 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 35/98 (35%), Gaps = 3/98 (3%) Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTI 229 L K + + G G +G V G V +V+ L + + + K KK Sbjct: 14 LVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK---KF 70 Query: 230 LTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAI 267 K + +++ + D + + V++AI Sbjct: 71 AENPKAGDEFVEKTLSSISTSTDAASVVHSTDLVVEAI 108 >2ZXH-A nrPDB Length = 637 Score = 37.6 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 31/151 (20%), Positives = 54/151 (35%), Gaps = 10/151 (6%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTA--IVEPKYWGGVCLN--VGCIPSKALLRNAE- 57 +DVVV+G G G AA+ AA++G TA ++ G + N +G I ++R + Sbjct: 27 EFDVVVIGGGHAGIEAALAAARMGAKTAMFVLNADTIGQMSCNPAIGGIAKGIVVREIDA 86 Query: 58 LVHIFTKDAKAFGISGEV--TFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTF 115 L K GI ++ T + + R + +N+ Sbjct: 87 LGGEMGKAIDQTGIQFKMLNTRKGKAVQSPRAQADKKRYREYMKKVCENQENLYIKQEEV 146 Query: 116 AD---ANTLLVDLNDGGTESVTFDNAIIATG 143 D N +V + ++ TG Sbjct: 147 VDIIVKNNQVVGVRTNLGVEYKTKAVVVTTG 177 Score = 28.7 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 10/28 (35%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIV 200 +++ G G G+E G + Sbjct: 29 DVVVIGGGHAGIEAALAAARMGAKTAMF 56 >1SEZ-A nrPDB Length = 504 Score = 37.2 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 37/89 (41%), Gaps = 11/89 (12%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 K + + GAG G+ Y LK +G++VT+ E +A + + G ++ Sbjct: 14 KRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGK---------LRSVSQDG--LIW 62 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKA 260 ++ + VT + G+ ++ + Sbjct: 63 DEGANTMTESEGDVTFLIDSLGLREKQQF 91 Score = 35.3 bits (80), Expect = 0.059, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 17/35 (48%), Gaps = 1/35 (2%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP-KYWGG 39 V V+GAG G AA + GL+ + E GG Sbjct: 16 VAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGG 50 >4K2X-A nrPDB Length = 523 Score = 36.8 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 17/33 (51%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP 34 YDVV+ GAGP G + A G T ++E Sbjct: 21 MRYDVVIAGAGPTGLMLACELRLAGARTLVLER 53 Score = 29.9 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 16/34 (47%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 ++IAGAG G+ L+ G ++E L Sbjct: 24 DVVIAGAGPTGLMLACELRLAGARTLVLERLAEP 57 >2GAG-B nrPDB Length = 405 Score = 36.4 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 26/64 (40%), Gaps = 4/64 (6%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLG--LSTAIVEPKYW-GGVCL-NVGCIPSKALLRNAE 57 YD +++G G G A A+ + A++E + GG N I S L + Sbjct: 20 KSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLWDESA 79 Query: 58 LVHI 61 ++ Sbjct: 80 GIYE 83 >4MO2-B nrPDB Length = 368 Score = 36.4 bits (83), Expect = 0.028, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 22/39 (56%), Gaps = 1/39 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY-WGGVC 41 YD +++G+G G + A A + G + +VE + GG C Sbjct: 2 YDYLIVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGNC 40 >4UDQ-A nrPDB Length = 531 Score = 36.4 bits (83), Expect = 0.030, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 18/35 (51%), Gaps = 1/35 (2%) Query: 2 THYDVVVLGAGPGGYVAAIR-AAQLGLSTAIVEPK 35 T +D V++G G G V A R +A+ ++E Sbjct: 4 TIFDYVIVGGGTAGSVLANRLSARPENRVLLIEAG 38 >3G5Q-A nrPDB Length = 443 Score = 36.0 bits (82), Expect = 0.034, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 18/36 (50%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRAL 207 + + + GAG G E + L GV V + E P+ + Sbjct: 2 ERVNVVGAGLAGSEAAWTLLRLGVPVRLFEMRPKRM 37 >3CP8-A nrPDB Length = 641 Score = 36.0 bits (82), Expect = 0.037, Method: Composition-based stats. Identities = 13/29 (44%), Positives = 19/29 (65%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIV 32 YDV+V+GAG G AA+ A+ GL ++ Sbjct: 22 YDVIVVGAGHAGCEAALAVARGGLHCLLI 50 >6ER9-A nrPDB Length = 549 Score = 35.6 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 32/217 (14%), Positives = 64/217 (29%), Gaps = 30/217 (13%) Query: 5 DVVVLGAGPGGYVAAIRA-AQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIF 62 D VV+GAG GG A + + GL+ + GG Sbjct: 11 DAVVIGAGFGGIYAVHKLHNEQGLTVVGFDKADGPGGT------------WYWNRYPGAL 58 Query: 63 TK-DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGT------- 114 + ++ + S + + + + + ++ + + +GT Sbjct: 59 SDTESHLYRFSFDRDLLQDGTWKTTYITQPEILEYLESVVDRFDLRRHFRFGTEVTSAIY 118 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATG----SSTRLVPGTSLSANVVTYEEQILSRE- 169 D N V + G E + A G + +PG + + Sbjct: 119 LEDENLWEVSTDKG--EVYRAKYVVNAVGLLSAINFPDLPGLDTFEGETIHTAAWPEGKN 176 Query: 170 -LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPR 205 K + + G G+ G + L +T+ P+ Sbjct: 177 LAGKRVGVIGTGSTGQQVITALAPEVEHLTVFVRTPQ 213 >3KYB-A nrPDB Length = 390 Score = 35.6 bits (81), Expect = 0.047, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 15/36 (41%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 K I+I GAG G G L G V I++ Sbjct: 3 SKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHI 38 >1X14-A nrPDB Length = 401 Score = 35.6 bits (81), Expect = 0.047, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 25/74 (33%) Query: 152 TSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNED 211 T + + P +++ GAG G+ + G V + P Sbjct: 153 AHEFGRFFTGQITAAGKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQ 212 Query: 212 ADVSKEIEKQFKKL 225 + ++ +E FK+ Sbjct: 213 SMGAEFLELDFKEE 226 >5MOG-A nrPDB Length = 497 Score = 35.3 bits (80), Expect = 0.052, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 15/35 (42%), Gaps = 1/35 (2%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVE-PKYWGG 39 VV+ GAG G A A G ++E GG Sbjct: 20 VVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGG 54 >6HRD-A nrPDB Length = 317 Score = 35.3 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 25/60 (41%) Query: 169 ELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVT 228 + + + + GAG +G V GV+VT+ E + + K +E+ VT Sbjct: 23 DAIQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLERAVSAGKVT 82 >4H7U-A nrPDB Length = 602 Score = 35.3 bits (80), Expect = 0.067, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 15/33 (45%), Gaps = 1/33 (3%) Query: 4 YDVVVLGAGPGGYVAAIRAAQ-LGLSTAIVEPK 35 YD +V G G G V A R ++ ++E Sbjct: 41 YDFIVAGGGTAGLVVASRLSENSNWKVLVIEAG 73 >4Z2R-A nrPDB Length = 592 Score = 34.9 bits (79), Expect = 0.073, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 20/30 (66%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEP 34 DV+++GAGP G ++A A LG+ + ++ Sbjct: 14 DVLIVGAGPAGAMSATLLASLGIRSLMINR 43 >3UKH-A nrPDB Length = 519 Score = 34.9 bits (79), Expect = 0.074, Method: Composition-based stats. Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 2/37 (5%) Query: 5 DVVVLGAGPGGYVAAIRAAQL-GLSTAIVEP-KYWGG 39 DV+V+GAGP G AA R Q+ G S IV+ + GG Sbjct: 8 DVLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNETPGG 44 >5AYV-A nrPDB Length = 309 Score = 34.9 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 34/95 (35%), Gaps = 23/95 (24%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTA 232 I + GAG+IG FG +L G DVT++ + K G+ + Sbjct: 2 RIYVLGAGSIGSLFGALLARAGNDVTLIGRREQV-------------DAINKNGLHVF-- 46 Query: 233 TKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAI 267 G + TV A E + ++ A+ Sbjct: 47 --------GAEEFTVKPKATIYAPEEPPDLLILAV 73 >1FOH-A nrPDB Length = 664 Score = 34.9 bits (79), Expect = 0.076, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 20/36 (55%), Gaps = 5/36 (13%) Query: 5 DVVVLGAGPGGYVAAIRAAQL-----GLSTAIVEPK 35 DV+++GAGP G +AA ++ L I++ + Sbjct: 9 DVLIVGAGPAGLMAARVLSEYVRQKPDLKVRIIDKR 44 >3COX-A nrPDB Length = 507 Score = 34.9 bits (79), Expect = 0.078, Method: Composition-based stats. Identities = 29/117 (24%), Positives = 41/117 (35%), Gaps = 30/117 (25%) Query: 7 VVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGV----------CLNVGCIPSKALLRNA 56 +V+G+G GG VAA+R Q G+ T IVE LN P K + A Sbjct: 15 LVIGSGYGGAVAALRLTQAGIPTQIVEMGRSWDTPGSDGKIFCGMLN----PDKRSMWLA 70 Query: 57 ELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYG 113 + + FGI+ + R GV + + I G G Sbjct: 71 DKTDQPVSNFMGFGINKSID----------------RYVGVLDSERFSGIKVYQGRG 111 >6ACQ-A nrPDB Length = 302 Score = 34.9 bits (79), Expect = 0.085, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 37/95 (38%), Gaps = 9/95 (9%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 K + + GAG +G G +V + + + ++K + K KK + Sbjct: 22 KKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIE--E 79 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQA 266 ATKVE + V + + D + V++A Sbjct: 80 ATKVEILTRISGTVDLNMAAD-------CDLVIEA 107 >2Y0D-A nrPDB Length = 478 Score = 34.5 bits (78), Expect = 0.095, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 37/103 (35%), Gaps = 12/103 (11%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTA 232 ++ I G+G +G+ G L + G DV DV + GV I Sbjct: 10 NLTIIGSGKVGLVTGACLADIGHDV------------FCLDVDQAKIDILNNGGVPIHEP 57 Query: 233 TKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEG 275 E IA S + + D A + A+G P+ +G Sbjct: 58 GLKEVIARNRSAGRLRFSTDIEAAVAHGDVQFIAVGTPPDEDG 100 >6H3G-A nrPDB Length = 651 Score = 34.5 bits (78), Expect = 0.096, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 16/34 (47%), Gaps = 2/34 (5%) Query: 5 DVVVLGAGPGGYVAAIRAAQLG--LSTAIVEPKY 36 DV+V G GP G V A R A L ++E Sbjct: 8 DVIVCGGGPAGCVVAGRLAYADPTLKVMLIEGGA 41 >5EZ7-A nrPDB Length = 392 Score = 34.5 bits (78), Expect = 0.100, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 18/35 (51%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGG 39 D++++G G G R + G +T +VE GG Sbjct: 9 DILIVGGGIAGLWLNARLRRAGYATVLVESASLGG 43 >3Q9T-A nrPDB Length = 577 Score = 34.5 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 19/35 (54%), Gaps = 1/35 (2%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQL-GLSTAIVEPK 35 +H+D V++G G G A R A+ ++ IVE Sbjct: 5 SHFDFVIVGGGTAGNTVAGRLAENPNVTVLIVEAG 39 >1GPE-A nrPDB Length = 587 Score = 34.1 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 15/37 (40%), Gaps = 1/37 (2%) Query: 2 THYDVVVLGAGPGGYV-AAIRAAQLGLSTAIVEPKYW 37 YD ++ G G G AA + ++E ++ Sbjct: 23 KTYDYIIAGGGLTGLTVAAKLTENPKIKVLVIEKGFY 59 >5XGV-A nrPDB Length = 462 Score = 34.1 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRAL-PNEDADVSKEIEKQFKKLGV 227 ++IIAG G +G+ L GVD ++E P+ ++ + + F + G+ Sbjct: 1 SDTVIIAGGGPVGLMLACELGLAGVDTVVLERHDAPREPSRGGAINATVVELFTQRGI 58 Score = 30.3 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 16/32 (50%), Gaps = 1/32 (3%) Query: 5 DVVVL-GAGPGGYVAAIRAAQLGLSTAIVEPK 35 D V++ G GP G + A G+ T ++E Sbjct: 2 DTVIIAGGGPVGLMLACELGLAGVDTVVLERH 33 >1VRQ-A nrPDB Length = 964 Score = 34.1 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 58/293 (19%), Positives = 92/293 (31%), Gaps = 57/293 (19%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIV-EPKYWGGVCLNVGCIPSKALLRNAELVHI 61 H DV+V+GAGP G AA A++ G ++ E GG L Sbjct: 127 HTDVLVVGAGPAGLAAAREASRSGARVMLLDERPEAGGT-----------------LREA 169 Query: 62 FTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTL 121 + + + R + I T+ Sbjct: 170 SGEQIDGIDAAQWIDAVTEELAAAEETTHLQRTT----VFGSYDANYILAAQR----RTV 221 Query: 122 LVDLNDGGTES------VTFDNAIIATGSSTRLV-------PGTSLSANVVTYEEQILSR 168 +D G S + ++AT + R + PG L+ +V +Y + R Sbjct: 222 HLDGPSGQGVSRERIWHIRAKQVVLATAAHERPIVFENNDRPGIMLAGSVRSYLNRFGVR 281 Query: 169 ELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVT 228 K I +A L G V +++ V+ GVT Sbjct: 282 AGSK-IAVATTNDSVYPLVSELAASGGVVAVIDARQNISAAAAQAVTD---------GVT 331 Query: 229 ILTATKV---ESIADGGSQVTVTVTKD-----GVAQELKAEKVLQAIGFAPNV 273 +LT + V E+ A G + T D G AQ +A+ + + GF P V Sbjct: 332 VLTGSVVANTEADASGELSAVLVATLDEQRNLGEAQRFEADVLAVSGGFNPVV 384 >4A7P-A nrPDB Length = 446 Score = 34.1 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 33/96 (34%), Gaps = 12/96 (12%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTA 232 I + G G +G+ G ++G +V V+ R + +V E L Sbjct: 10 RIAMIGTGYVGLVSGACFSDFGHEVVCVDKDARKIELLHQNVMPIYEPGLDAL------- 62 Query: 233 TKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIG 268 +A ++ T D A+ V A+G Sbjct: 63 -----VASNVKAGRLSFTTDLAEGVKDADAVFIAVG 93 >3F3S-A nrPDB Length = 313 Score = 34.1 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLG 226 ++I G+G IG + + + G V + + + + N ++ KE+ K ++ G Sbjct: 6 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEM-KLLEQAG 57 >1RP0-A nrPDB Length = 284 Score = 34.1 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 5 DVVVLGAGPGGYVAAIRAAQL-GLSTAIVEPK-YWGG 39 DVVV+GAG G AA ++ + AI+E GG Sbjct: 41 DVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGG 77 >5KOX-A nrPDB Length = 476 Score = 33.7 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 17/31 (54%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK 35 DV++ G GP G + A G+ T ++E + Sbjct: 6 DVIIAGGGPTGLMLAGELRLHGVRTVVLEKE 36 Score = 29.5 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 27/70 (38%), Gaps = 10/70 (14%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP--------RALPNEDADVSKE--IEKQF 222 +IIAG G G+ L+ +GV ++E P R L +V + + ++F Sbjct: 6 DVIIAGGGPTGLMLAGELRLHGVRTVVLEKEPTPNQHSRSRGLHARSIEVMDQRGLLERF 65 Query: 223 KKLGVTILTA 232 G Sbjct: 66 LAHGEQFRVG 75 >4MIF-A nrPDB Length = 620 Score = 33.7 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 14/30 (46%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 YDV + G+GP G A L +VE Sbjct: 14 YDVFIAGSGPIGATFAKLCVDANLRVCMVE 43 >3BI4-A nrPDB Length = 516 Score = 33.7 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGV-DVTIVEFLPRA 206 K +II GAG G++ L G+ D ++E R Sbjct: 9 KKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRV 44 >3FPZ-A nrPDB Length = 326 Score = 33.7 bits (76), Expect = 0.20, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 3/38 (7%) Query: 5 DVVVLGAGPGGYVAAIRAAQL--GLSTAIVEPK-YWGG 39 DV+++GAG G AA A+ L I+E GG Sbjct: 67 DVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGG 104 >6MO6-A nrPDB Length = 414 Score = 33.3 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 26/177 (14%), Positives = 48/177 (27%), Gaps = 24/177 (13%) Query: 215 SKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVT-KDGVAQELKAEKVLQAIGFAPNV 273 + +++ ++ +T+ + + + K G Q + E + P Sbjct: 203 ADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVT---PPMS 259 Query: 274 EGYGLDKAGVALTDRKAIGVDDY--MRTNVGHIYAIGDVNGLL---QLAHVAEAQG---V 325 L + VA + VD +++ IGD L A VA G Sbjct: 260 PPDVLKTSPVA-DAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDR 318 Query: 326 VAAETIAGAETLTLGD-HRMLPRATFCQPNVASFGLTEQQARNEGYDVV-VAKFPFT 380 + + D + P G Y + FPF Sbjct: 319 TISVIMKNQTPTKKYDGYTSCPLV---------TGYNRVILAEFDYKAEPLETFPFD 366 >4YNU-A nrPDB Length = 571 Score = 33.3 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQL-GLSTAIVEPKY 36 T YD +V+G G G V A R ++ +S ++E Sbjct: 4 TTYDYIVVGGGTSGLVVANRLSENPDVSVLLLEAGA 39 >3ADO-A nrPDB Length = 319 Score = 33.3 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 27/55 (49%), Gaps = 1/55 (1%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLG 226 ++I G+G +G + + + G V + + PR + ++ KE+ K ++ G Sbjct: 7 GDVLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALENIRKEM-KSLQQSG 60 Score = 30.3 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAI--VEPKYWGGVCLNV 44 DV+++G+G G A+ A G + +EP+ G N+ Sbjct: 8 DVLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALENI 49 >5X6R-A nrPDB Length = 420 Score = 33.3 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 29/73 (39%), Gaps = 5/73 (6%) Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEK---QFKKLG 226 + +S+ I GAG +G G +VT+ +F P D +K ++ G Sbjct: 27 MSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQD--PRLDTTKNKNLKSINLAISARG 84 Query: 227 VTILTATKVESIA 239 + L + ++ Sbjct: 85 IDALKSIDPDACE 97 >2QA2-A nrPDB Length = 499 Score = 33.3 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 14/33 (42%), Positives = 21/33 (63%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPR 205 S+I+ GAG G+ L+ GVDV ++E LP+ Sbjct: 14 SVIVVGAGPAGLMLAGELRLGGVDVMVLEQLPQ 46 Score = 28.7 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 16/28 (57%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 V+V+GAGP G + A G+ ++E Sbjct: 15 VIVVGAGPAGLMLAGELRLGGVDVMVLE 42 >3OZ2-A nrPDB Length = 397 Score = 33.0 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 22/42 (52%) Query: 17 VAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAEL 58 AA AA+ GL T ++E + G + G SK +L A++ Sbjct: 18 TAARYAAKYGLKTLMIEKRPEIGSPVRCGEGLSKGILNEADI 59 >6J0Z-C nrPDB Length = 491 Score = 33.0 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDAD-VSKEIEKQFKKLGVTILT 231 +++ GAG G+ L+ GV V +++ L + A S ++F + G+ Sbjct: 7 DVVVVGAGPTGLMLAGELRLAGVSVVVLDKLAEPIKESRALGFSARTIEEFAQRGLMDRF 66 Query: 232 ATK 234 Sbjct: 67 GEV 69 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 18/30 (60%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEP 34 DVVV+GAGP G + A G+S +++ Sbjct: 7 DVVVVGAGPTGLMLAGELRLAGVSVVVLDK 36 >4RG3-A nrPDB Length = 548 Score = 33.0 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 33/217 (15%), Positives = 67/217 (30%), Gaps = 30/217 (13%) Query: 5 DVVVLGAGPGGYVAAIRA-AQLGLSTAIVEP-KYWGGVCLNVGCIPSKALLRNAELVHIF 62 D VV+GAG GG A + +LGL+T + GG Sbjct: 18 DAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGGT------------WYWNRYPGAL 65 Query: 63 TK-DAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGT------- 114 + ++ + S + + + + + ++ + + +GT Sbjct: 66 SDTESHLYRFSFDRDLLQESTWKTTYITQPEILEYLEDVVDRFDLRRHFKFGTEVTSALY 125 Query: 115 FADANTLLVDLNDGGTESVTFDNAIIATGSSTRL----VPGTSLSANVVTYEEQILSRE- 169 D N V + G E + A G + + +PG + + Sbjct: 126 LDDENLWEVTTDHG--EVYRAKYVVNAVGLLSAINFPNLPGLDTFEGETIHTAAWPEGKS 183 Query: 170 -LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPR 205 + + + G G+ G + L +T+ P+ Sbjct: 184 LAGRRVGVIGTGSTGQQVITSLAPEVEHLTVFVRTPQ 220 >5L46-A nrPDB Length = 841 Score = 33.0 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 26/93 (27%), Gaps = 15/93 (16%) Query: 7 VVLGAGPGGYVAAIRAAQLGLS-TAIVEPKYW--GGVCLNVGCIPSKALLRNAELVHIFT 63 V++G G G A A+ G+ ++E G A L F Sbjct: 26 VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGST------------WHAAGLTTYFH 73 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAG 96 I + Y + + +V G Sbjct: 74 PGINLKKIHYDSIKLYEKLEEETGQVVGFHQPG 106 >3GG2-A nrPDB Length = 450 Score = 33.0 bits (74), Expect = 0.32, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 35/107 (32%), Gaps = 10/107 (9%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDA---DVSKEIEKQFKKLGVT- 228 I + G G +G+ G +V ++ + ++ + + ++ V Sbjct: 4 DIAVVGIGYVGLVSATCFAELGANVRCIDTDRNKIEQLNSGTIPIYEPGLEKMIARNVKA 63 Query: 229 --ILTATKVESIADGGSQVTVTV-TKDGVAQELKAEKVLQA---IGF 269 + T++E + + V T G VL A IG Sbjct: 64 GRLRFGTEIEQAVPEADIIFIAVGTPAGEDGSADMSYVLDAARSIGR 110 >5I68-A nrPDB Length = 663 Score = 33.0 bits (74), Expect = 0.33, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 16/36 (44%), Gaps = 2/36 (5%) Query: 3 HYDVVVLGAGPGGYVAAIRAA--QLGLSTAIVEPKY 36 +D++VLG G G A R A L ++E Sbjct: 6 EFDILVLGGGSSGSCIAGRLANLDHSLKVGLIEAGE 41 >2DKH-A nrPDB Length = 639 Score = 32.6 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 15/33 (45%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 5 DVVVLGAGPGGYV-AAIRAAQLGLSTAIVEPKY 36 DV+++G GP G AA AA + T IVE K Sbjct: 34 DVLIVGCGPAGLTLAAQLAAFPDIRTCIVEQKE 66 >4RPJ-A nrPDB Length = 399 Score = 32.6 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 21/38 (55%), Gaps = 2/38 (5%) Query: 4 YDVVVLGAGPGGYVAAIR-AAQLGLSTAIVEPK-YWGG 39 +D+ V+G+G G A R A QL ++E + + GG Sbjct: 8 FDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGG 45 Score = 28.3 bits (62), Expect = 6.9, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 13/35 (37%), Gaps = 1/35 (2%) Query: 173 SIIIAGAGAIGMEFGY-VLKNYGVDVTIVEFLPRA 206 + + G+G G+ V V ++E P Sbjct: 9 DLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHI 43 >5EB4-A nrPDB Length = 532 Score = 32.6 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 14/34 (41%), Gaps = 1/34 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW 37 YD +V+G G G A ++ ++E Sbjct: 27 YDYIVIGGGTSGCPLAATLSE-KYKVLLLERGTI 59 >4Z25-A nrPDB Length = 652 Score = 32.6 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 17/32 (53%), Gaps = 1/32 (3%) Query: 5 DVVVLGAGPGGYVAAIRAAQ-LGLSTAIVEPK 35 D+V++GAG G + A A+ + ++E Sbjct: 8 DIVIIGAGAAGSLLAHYLARFSNMKIILLEAG 39 >4U2L-A nrPDB Length = 510 Score = 32.2 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 18/31 (58%) Query: 7 VVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW 37 VV+G G G V+A+R + G+ T ++E Sbjct: 9 VVIGTGYGAAVSALRLGEAGVQTLMLEMGQL 39 >4IV9-A nrPDB Length = 557 Score = 32.2 bits (72), Expect = 0.49, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 19/54 (35%), Gaps = 6/54 (11%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGV-DVTIVEFLPRALPN-----EDADVSKEIEK 220 + I GAG G+ L GV DV + E R D + I + Sbjct: 40 RVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAE 93 >4N9X-A nrPDB Length = 411 Score = 32.2 bits (72), Expect = 0.52, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 17/36 (47%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY 36 M +DVV+ G G G A GL A++E + Sbjct: 1 MQSFDVVIAGGGMVGLALACGLQGSGLRIAVLEKQA 36 Score = 28.7 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 17/29 (58%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVE 201 ++IAG G +G+ L+ G+ + ++E Sbjct: 5 DVVIAGGGMVGLALACGLQGSGLRIAVLE 33 >1LQU-A nrPDB Length = 456 Score = 32.2 bits (72), Expect = 0.52, Method: Composition-based stats. Identities = 29/199 (14%), Positives = 63/199 (31%), Gaps = 29/199 (14%) Query: 44 VGCIPSKALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKK 103 VG PS A A L+ + ++ ++ + R + + K+ Sbjct: 9 VGSGPS-AFFAAASLL-KAADTTEDLDMAVDMLEMLPTPWGLVRSGVAPDHPKIKSISKQ 66 Query: 104 NKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGS---STRLVPGTSLSANVVT 160 + T F N ++ + G S +D I A G+ +PG L ++ Sbjct: 67 FEKTAEDPRFRFFG-NVVVGEHVQPGELSERYDAVIYAVGAQSDRMLNIPGEDLPGSIAA 125 Query: 161 YE-----------EQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPN 209 + EQ+ ++ G G + ++ +L D ++ Sbjct: 126 VDFVGWYNAHPHFEQVSPDLSGARAVVIGNGNVALDVARILL---TDPDVLAR------- 175 Query: 210 EDADVSKEIEKQFKKLGVT 228 D++ + + G+ Sbjct: 176 --TDIADHALESLRPRGIQ 192 >5X68-A nrPDB Length = 391 Score = 32.2 bits (72), Expect = 0.56, Method: Composition-based stats. Identities = 6/33 (18%), Positives = 11/33 (33%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP 204 K + + G G +G L + + E Sbjct: 15 KKVAVIGGGLVGSLQACFLAKRNFQIDVYEARE 47 >2BS2-A nrPDB Length = 660 Score = 32.2 bits (72), Expect = 0.56, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 17/28 (60%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIV 32 D +V+G G G AA+ Q GLST ++ Sbjct: 7 DSLVIGGGLAGLRAAVATQQKGLSTIVL 34 >3IHM-A nrPDB Length = 430 Score = 31.8 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 13/30 (43%), Positives = 18/30 (60%) Query: 170 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTI 199 + K I I GAG G+ G L+ + VDVT+ Sbjct: 21 MKKRIGIVGAGTAGLHLGLFLRQHDVDVTV 50 >5TUF-A nrPDB Length = 409 Score = 31.8 bits (71), Expect = 0.58, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW---GGVCLNVGCI 47 H ++V+G G G A + G S ++E GG L++ I Sbjct: 24 KHIKILVIGVGVAGPAVAYWLKRFGFSPVLIEKSAAVRKGGQALDIRGI 72 >1GDH-A nrPDB Length = 320 Score = 31.8 bits (71), Expect = 0.59, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 40/120 (33%), Gaps = 16/120 (13%) Query: 271 PNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAA-- 328 P + +KA + + AI V+ A GD+ +L A G +A Sbjct: 214 PETRYF-FNKATIKSLPQGAIVVNT----------ARGDLVDN-ELVVAALEAGRLAYAG 261 Query: 329 -ETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHG 387 + AG + G + + F A+ E A D++ A F + A Sbjct: 262 FDVFAGEPNINEGYYDLPNTFLFPHIGSAATQAREDMAHQAN-DLIDALFGGADMSYALA 320 >1J49-A nrPDB Length = 333 Score = 31.8 bits (71), Expect = 0.60, Method: Composition-based stats. Identities = 16/102 (15%), Positives = 33/102 (32%), Gaps = 8/102 (7%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + + G G IG F +++ +G V N + + + Sbjct: 149 VGVVGTGHIGQVFMQIMEGFGAKV----ITYDIFRNPELEKKGYYVDSLD----DLYKQA 200 Query: 234 KVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEG 275 V S+ V + D ++K + V+ + P V+ Sbjct: 201 DVISLHVPDVPANVHMINDESIAKMKQDVVIVNVSRGPLVDT 242 >5XMJ-A nrPDB Length = 627 Score = 31.8 bits (71), Expect = 0.65, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 16/30 (53%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIV 32 H DV+ +G G A+ A+ GL T ++ Sbjct: 5 HTDVLCIGGALAGERVAVEASMAGLKTIML 34 >4IIN-A nrPDB Length = 271 Score = 31.4 bits (70), Expect = 0.82, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 26/58 (44%), Gaps = 8/58 (13%) Query: 172 KSIIIAGAGA-IGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVT 228 K+++I GA IG E L + G+ V +A+V+ ++ + ++ G Sbjct: 30 KNVLITGASKGIGAEIAKTLASMGLKV-------WINYRSNAEVADALKNELEEKGYK 80 >4K22-A nrPDB Length = 365 Score = 31.4 bits (70), Expect = 0.82, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 15/31 (48%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFL 203 + I G G +G+ L+ G+ V ++E Sbjct: 5 DVAIVGGGMVGLAVACGLQGSGLRVAVLEQR 35 Score = 30.6 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 16/35 (45%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPK 35 M DV ++G G G A GL A++E + Sbjct: 1 MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQR 35 >4B4O-A nrPDB Length = 298 Score = 31.4 bits (70), Expect = 0.88, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 16/37 (43%), Gaps = 1/37 (2%) Query: 173 SIIIAGA-GAIGMEFGYVLKNYGVDVTIVEFLPRALP 208 +++ G G IG +L G +VT+V P Sbjct: 2 RVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGR 38 >3CP2-A nrPDB Length = 649 Score = 31.4 bits (70), Expect = 0.92, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 20/29 (68%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIV 32 +DV+++G G G AA+ AA++G T ++ Sbjct: 27 FDVIIIGGGHAGTEAAMAAARMGQQTLLL 55 >4HA6-A nrPDB Length = 508 Score = 31.4 bits (70), Expect = 0.96, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 15/33 (45%), Gaps = 1/33 (3%) Query: 5 DVVVLGAGPGG-YVAAIRAAQLGLSTAIVEPKY 36 D+V++G G G +AA + ++E Sbjct: 3 DIVIVGGGSAGSLLAARLSEDPDSRVLLIEAGE 35 >2WTB-A nrPDB Length = 725 Score = 31.4 bits (70), Expect = 0.96, Method: Composition-based stats. Identities = 17/106 (16%), Positives = 34/106 (32%), Gaps = 9/106 (8%) Query: 162 EEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQ 221 ++ L K + I G G +G L V + E + L V ++ + Sbjct: 303 TDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSR 362 Query: 222 FKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAI 267 +K ++ K S+ G + V++A+ Sbjct: 363 VRKGSMSQEKFEKTMSLLKGSLD---------YESFRDVDMVIEAV 399 >3G05-A nrPDB Length = 576 Score = 31.0 bits (69), Expect = 1.00, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 20/29 (68%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIV 32 +DV+++G G G AA+ AA++G T ++ Sbjct: 33 FDVIIIGGGHAGTEAAMAAARMGQQTLLL 61 >2BKW-A nrPDB Length = 385 Score = 31.0 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 28/63 (44%) Query: 141 ATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIV 200 A+ S ++ G+ + ILS+ K++++ G F L++YG V +V Sbjct: 56 ASKSQPFVLAGSGTLGWDIFASNFILSKAPNKNVLVVSTGTFSDRFADCLRSYGAQVDVV 115 Query: 201 EFL 203 L Sbjct: 116 RPL 118 >6DLL-A nrPDB Length = 398 Score = 31.0 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 32/88 (36%), Gaps = 7/88 (7%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTAT 233 + I GAG G+ G +L G+D IVE + + + ++ V +L Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIVERQ-----TAEYVLGRIRAGVLEQGTVDLLREA 62 Query: 234 KVESIADGGSQVT--VTVTKDGVAQELK 259 V D V V + G Q L Sbjct: 63 GVAERMDREGLVHEGVELLVGGRRQRLD 90 >4P9S-A nrPDB Length = 848 Score = 31.0 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 26/93 (27%), Gaps = 15/93 (16%) Query: 7 VVLGAGPGGYVAAIRAAQLGLS-TAIVEPKYW--GGVCLNVGCIPSKALLRNAELVHIFT 63 V++G G G A A+ G+ ++E G A L F Sbjct: 27 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGST------------WHAAGLTTYFH 74 Query: 64 KDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAG 96 I + Y + + +V G Sbjct: 75 PGINLKKIHYDSIKLYERLEEETGQVVGFHQPG 107 >3KKJ-A nrPDB Length = 336 Score = 31.0 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 19/66 (28%), Gaps = 5/66 (7%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNE-----DADVSKEIEKQFKKLGVT 228 I I G G G+ L G V + + + DA + F Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFDKSRGSGGRMSSKRSDAGALDMGAQYFTARDRR 64 Query: 229 ILTATK 234 TA K Sbjct: 65 FATAVK 70 >4KUG-A nrPDB Length = 290 Score = 31.0 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 23/57 (40%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVT 228 K + + GAG +G G +V + + + A ++K + K K +T Sbjct: 2 KKVFVLGAGTMGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKEKIT 58 >4XRR-A nrPDB Length = 456 Score = 31.0 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 36/104 (34%), Gaps = 10/104 (9%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDV--------TIVEFLPRALPNEDADVSKEIEKQF 222 P ++IAGAG +G L G +V T+ + + ++ + Sbjct: 15 PLKVVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEPGLAGAVRD-L 73 Query: 223 KKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQA 266 G + +T + + + T E+ ++++ A Sbjct: 74 AATG-RLTASTSYDPVGAADVVIVTVGTPTDAGHEMVTDQLVAA 116 >1E3J-A nrPDB Length = 352 Score = 31.0 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 14/26 (53%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAI 31 V+V+GAGP G V+ + A G Sbjct: 172 VLVIGAGPIGLVSVLAAKAYGAFVVC 197 >4EIQ-A nrPDB Length = 549 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 31/78 (39%), Gaps = 10/78 (12%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALL--RNAELV--H 60 DV++LG GP G A+ A + +V+ G + P + + R+ EL Sbjct: 28 DVLILGGGPVGMALALDLAHRQVGHLVVDAGD--GTITH----PKVSTIGPRSMELFRRW 81 Query: 61 IFTKDAKAFGISGEVTFD 78 K + G G+ D Sbjct: 82 GVAKQIRTAGWPGDHPLD 99 >4ZCC-A nrPDB Length = 336 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 9/52 (17%), Positives = 15/52 (28%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKL 225 I I G G G+ L + G V + + + + S Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFDKSRGSGGRMSSKRSDAGSLDMGAQ 56 >4Z44-A nrPDB Length = 554 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 19/35 (54%), Gaps = 3/35 (8%) Query: 6 VVVLGAGPGGYVAA---IRAAQLGLSTAIVEPKYW 37 +V++G G G++AA +RA Q + ++E Sbjct: 24 IVIVGGGTAGWMAASYLVRALQQQANITLIESAAI 58 >3HN2-A nrPDB Length = 312 Score = 30.6 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 18/32 (56%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP 204 I I GAGA+G+ +G +L+ G DV + Sbjct: 4 RIAIVGAGALGLYYGALLQRSGEDVHFLLRRD 35 >1QU3-A nrPDB Length = 917 Score = 30.6 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 34/87 (39%), Gaps = 4/87 (4%) Query: 181 AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLG--VTILTATKVESI 238 I +E +YG D+ +E + V +I KL + + TA +V S Sbjct: 711 FINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSH 770 Query: 239 ADGGSQVTVTVTKDGVAQELKAEKVLQ 265 + +V + + + ++ ++ L Sbjct: 771 TPHVKEESVHLAD--MPKVVEVDQALL 795 >3RED-A nrPDB Length = 521 Score = 30.6 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 14/34 (41%), Gaps = 1/34 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW 37 YD V++G G G A ++ ++E Sbjct: 27 YDYVIVGGGTSGCPLAATLSE-KYKVLVLERGTL 59 >6IUM-B nrPDB Length = 701 Score = 30.6 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 28/99 (28%), Positives = 38/99 (38%), Gaps = 5/99 (5%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 + + + GAG +G N G+ VTI+E AL + K E KK LT Sbjct: 293 EKVAVIGAGTMGGGISMNFLNAGIPVTILETKQEALDRGVGIIRKNYENSAKKGK---LT 349 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFA 270 KVE G T D +L E V + +G Sbjct: 350 QEKVEQ--RMGLLSTTLSYDDLKDADLIIEAVFEEMGVK 386 >1LTX-R nrPDB Length = 650 Score = 30.6 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 21/38 (55%), Gaps = 3/38 (7%) Query: 4 YDVVVLGAG-PGGYVAAIRAAQLGLSTAIVE-PKYWGG 39 +DV+V+G G P +AA ++ G V+ Y+GG Sbjct: 9 FDVIVIGTGLPESIIAAA-CSRSGQRVLHVDSRSYYGG 45 >3LOV-A nrPDB Length = 475 Score = 30.6 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 18/37 (48%), Gaps = 3/37 (8%) Query: 6 VVVLGAGPGGYVAAIRAAQL--GLSTAIVEPK-YWGG 39 +V++G G G AA A + L+ ++E GG Sbjct: 7 LVIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGG 43 Score = 29.1 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 16/39 (41%), Gaps = 4/39 (10%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYG---VDVTIVEFLPRA 206 K ++I G G G+ +++T++E R Sbjct: 4 SKRLVIVGGGITGL-AAAYYAERAFPDLNITLLEAGERL 41 >2RGJ-A nrPDB Length = 402 Score = 30.6 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGV-DVTIVEFLPRALP-NEDADVSKEIEKQFKKLGV 227 P I+IAGAG G+ L G+ VT++E P ++ + +LG+ Sbjct: 4 PIDILIAGAGIGGLSCALALHQAGIGKVTLLESSSEIRPLGVGINIQPAAVEALAELGL 62 >4FSH-A nrPDB Length = 271 Score = 30.6 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 18/39 (46%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNE 210 ++ +I G+G LK G+ V+++ PR L Sbjct: 119 QNALILGSGGSAKALACGLKKQGLKVSVLNRSPRGLDFF 157 >4FQ8-A nrPDB Length = 271 Score = 30.6 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 17/39 (43%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNE 210 ++ +I GAG LK G+ V+++ R L Sbjct: 119 QNALILGAGGSAKALACELKKQGLQVSVLNRSSRGLDFF 157 >1XFD-A nrPDB Length = 723 Score = 30.6 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 5/57 (8%) Query: 395 VKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQ 451 KL A A LG H + + E+ +A R + + + HPT E + Sbjct: 619 FKLYASAFSERYLGLHGLDNRAYEMTK---VAHRVSALEEQ--QFLIIHPTADEKIH 670 >5Y77-A nrPDB Length = 473 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 39/121 (32%), Gaps = 10/121 (8%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVT----- 228 + I GAG G +L G V + E P E + I + G Sbjct: 11 VTIIGAGLAGTLVARLLARNGWQVNLFERRPDP-RIETGARGRSINLALAERGAHALRLA 69 Query: 229 -ILTATKVESIADGGSQVTVTVTKDGVAQELKAEK-VLQAIGFAPNVEGY--GLDKAGVA 284 + E++ G V V T + + + V+ +I G + AG + Sbjct: 70 GLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGAS 129 Query: 285 L 285 + Sbjct: 130 I 130 >5NCC-A nrPDB Length = 594 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 15/34 (44%), Gaps = 1/34 (2%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLG-LSTAIVEPK 35 YD +++G G V A R + G ++E Sbjct: 23 KYDYILVGGGTAACVLANRLSADGSKRVLVLEAG 56 >3BA1-A nrPDB Length = 333 Score = 30.3 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 44/127 (34%), Gaps = 11/127 (8%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 K + I G G IG+ + + ++ + N S V + + Sbjct: 165 KRVGIIGLGRIGLAVAERAEAFDCPISYFSRSKKPNTNYTYYGSV----------VELAS 214 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAI 291 + + +A + T + V L + VL IG P+V+ L A V Sbjct: 215 NSDILVVACPLTPETTHIINREVIDALGPKGVLINIGRGPHVDEPELVSALVE-GRLGGA 273 Query: 292 GVDDYMR 298 G+D + R Sbjct: 274 GLDVFER 280 >5TUM-A nrPDB Length = 410 Score = 30.3 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYW---GGVCLNVGCI 47 + ++V+GAG G + G S ++E GG L+V I Sbjct: 24 KNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALDVRGI 72 >3JSK-A nrPDB Length = 344 Score = 30.3 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 3/38 (7%) Query: 5 DVVVLGAGPGGYVAAIRAAQL--GLSTAIVEPK-YWGG 39 D+V++GAG G AA + L L IVE GG Sbjct: 81 DIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGG 118 >2EEZ-A nrPDB Length = 369 Score = 30.3 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 19/41 (46%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNED 211 P S++I G G +G + G VTI++ + L D Sbjct: 166 PASVVILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQYLD 206 >3GDN-A nrPDB Length = 521 Score = 30.3 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 16/41 (39%), Gaps = 1/41 (2%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNV 44 YD V++G G G A ++ ++E NV Sbjct: 27 YDYVIVGGGTSGCPLAATLSE-KYKVLVLERGSLPTAYPNV 66 >1OCX-A nrPDB Length = 182 Score = 29.9 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 21/36 (58%) Query: 143 GSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAG 178 G + PG ++ NVV ++++++P ++++ G Sbjct: 138 GGRAVINPGVTIGDNVVVASGAVVTKDVPDNVVVGG 173 >1FW8-A nrPDB Length = 416 Score = 29.9 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 31/159 (19%), Positives = 50/159 (31%), Gaps = 24/159 (15%) Query: 53 LRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGY 112 + + F K + I G+ FD A + + + + GV ++ + I Sbjct: 162 IIGGGMAFTFKKVLENTEI-GDSIFDKAGAEIVPKLMEKAKAKGVEVVL---PVDFIIAD 217 Query: 113 GTFADANTLLVDLNDGG-------TESVTFDNAIIATGSSTRLV----PGTSLSANVVTY 161 ADANT V +G AT + + + P Sbjct: 218 AFSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAA 277 Query: 162 EEQILSRELPK-----SIIIAGAGAIGMEFGYVLKNYGV 195 + L E+ K + +I G G V K YGV Sbjct: 278 GTKALLDEVVKSSAAGNTVIIGGGDT----ATVAKKYGV 312 >2B76-A nrPDB Length = 602 Score = 29.9 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 10/22 (45%) Query: 289 KAIGVDDYMRTNVGHIYAIGDV 310 I D T + ++A+G+ Sbjct: 360 GGIETDQNCETRIKGLFAVGEC 381 >4JA9-A nrPDB Length = 488 Score = 29.9 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 24/72 (33%), Gaps = 7/72 (9%) Query: 283 VALTDRKAIGVD----DYMRTNVGHIYAIGDVNGLLQLAHVAEAQ--GVVAAETIAGAET 336 + L AI Y+RT YA+GD ++L A+ G Sbjct: 44 IELNPSNAIYYGNRSLAYLRTECYG-YALGDATRAIELDKKYIKGYYRRAASNMALGKFR 102 Query: 337 LTLGDHRMLPRA 348 L D+ + + Sbjct: 103 AALRDYETVVKV 114 >1QPG-A nrPDB Length = 415 Score = 29.9 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 31/159 (19%), Positives = 50/159 (31%), Gaps = 24/159 (15%) Query: 53 LRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGY 112 + + F K + I G+ FD A + + + + GV ++ + I Sbjct: 232 IIGGGMAFTFKKVLENTEI-GDSIFDKAGAEIVPKLMEKAKAKGVEVVL---PVDFIIAD 287 Query: 113 GTFADANTLLVDLNDGG-------TESVTFDNAIIATGSSTRLV----PGTSLSANVVTY 161 ADANT V +G AT + + + P Sbjct: 288 AFSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAA 347 Query: 162 EEQILSRELPK-----SIIIAGAGAIGMEFGYVLKNYGV 195 + L E+ K + +I G G V K YGV Sbjct: 348 GTKALLDEVVKSSAAGNTVIIGGGDT----ATVAKKYGV 382 >4REP-A nrPDB Length = 495 Score = 29.9 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 27/62 (43%), Gaps = 5/62 (8%) Query: 198 TIVEFLPRALPNEDAD-----VSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKD 252 T++ L L D +S+ + + +K+GV V +I ++VT TK+ Sbjct: 205 TMIPHLELGLGTYYPDGGMHRISQSLFELAQKVGVKFRFRESVTNITTSKNKVTGVETKN 264 Query: 253 GV 254 G Sbjct: 265 GS 266 >4D3F-A nrPDB Length = 310 Score = 29.9 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 14/28 (50%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTI 199 KS+ + G G +G V YG VT+ Sbjct: 22 KSVTVIGLGPMGQAMADVFLEYGYSVTV 49 >4R16-A nrPDB Length = 418 Score = 29.9 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 22/53 (41%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKL 225 I + G G IG+ + + G DV + + ++ V+ IE + + Sbjct: 2 RIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPEIDRR 54 >3I6D-A nrPDB Length = 470 Score = 29.9 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 19/42 (45%), Gaps = 8/42 (19%) Query: 172 KSIIIAGAGAIGMEFGYVL-------KNYGVDVTIVEFLPRA 206 K ++I G G G+ KN +++T+VE PR Sbjct: 6 KHVVIIGGGITGL-AAAFYMEKEIKEKNLPLELTLVEASPRV 46 Score = 28.3 bits (62), Expect = 7.1, Method: Composition-based stats. Identities = 7/16 (43%), Positives = 9/16 (56%) Query: 6 VVVLGAGPGGYVAAIR 21 VV++G G G AA Sbjct: 8 VVIIGGGITGLAAAFY 23 >2IVE-A nrPDB Length = 478 Score = 29.9 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 17/34 (50%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRA 206 ++ + G G G+ + L++ G D ++E R Sbjct: 18 NVAVVGGGISGLAVAHHLRSRGTDAVLLESSARL 51 Score = 28.3 bits (62), Expect = 6.9, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 28/85 (32%), Gaps = 7/85 (8%) Query: 207 LPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQA 266 L D + I+ LG +VE +A + + + G EL +V+ A Sbjct: 230 LSTFDGGLQVLIDALAASLGDAAHVGARVEGLAREDGGWRLIIEEHGRRAELSVAQVVLA 289 Query: 267 IG-------FAPNVEGYGLDKAGVA 284 P + AG+A Sbjct: 290 APAHATAKLLRPLDDALAALVAGIA 314 >2JFH-A nrPDB Length = 445 Score = 29.5 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 18/47 (38%), Gaps = 1/47 (2%) Query: 166 LSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDA 212 ++ K+++I G G G+ GV +++ P D Sbjct: 1 MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTP-PGLDK 46 >2CUL-A nrPDB Length = 232 Score = 29.5 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 10/27 (37%), Positives = 15/27 (55%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIV 200 ++I GAG G E + L GV V ++ Sbjct: 6 VLIVGAGFSGAETAFWLAQKGVRVGLL 32 Score = 29.5 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 17/32 (53%) Query: 1 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIV 32 M Y V+++GAG G A AQ G+ ++ Sbjct: 1 MAAYQVLIVGAGFSGAETAFWLAQKGVRVGLL 32 >3I83-A nrPDB Length = 320 Score = 29.5 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 18/32 (56%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP 204 +I++ G GAIG +G +L G V++V Sbjct: 4 NILVIGTGAIGSFYGALLAKTGHCVSVVSRSD 35 >1KYQ-A nrPDB Length = 274 Score = 29.5 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 26/63 (41%), Gaps = 2/63 (3%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIV--EFLPRALPNEDADVSKEIEKQFKKLGVTI 229 K I++ G G +G+ Y L G +T+V + +P + + + +++ Sbjct: 14 KRILLIGGGEVGLTRLYKLMPTGCKLTLVSPDLHKSIIPKFGKFIQNKDQPDYREDAKRF 73 Query: 230 LTA 232 + Sbjct: 74 INP 76 >5JBN-A nrPDB Length = 170 Score = 29.5 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 31/80 (38%), Gaps = 8/80 (10%) Query: 135 FDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYG 194 FD+ I+A +S P +L V ++ ++ + G + +N Sbjct: 32 FDHVILAIAASPSKKPMFTLEERVALAQQATAHL---GNVEVVGFSDL---MANFARNQ- 84 Query: 195 VDVTIVEFLPRALPNEDADV 214 T++ RA+ + + ++ Sbjct: 85 -HATVLIRGLRAVADFEYEM 103 >3RP7-A nrPDB Length = 407 Score = 29.5 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 17/32 (53%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEP 34 H +V+GAG GG AA+ Q G+ + E Sbjct: 23 HMKAIVIGAGIGGLSAAVALKQSGIDCDVYEA 54 >2ZJ1-A nrPDB Length = 495 Score = 29.5 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 44/211 (20%), Positives = 80/211 (37%), Gaps = 41/211 (19%) Query: 79 YGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNA 138 + + + V E GV L + + D +++ND T+S FDN Sbjct: 205 WTKIAESVKGVTEETTTGVLRLYQ---------FAAAGDLAFPAINVNDSVTKS-KFDNK 254 Query: 139 IIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVT 198 G+ L+ G + + + K ++I G G +G +K G V+ Sbjct: 255 Y---GTRHSLIDGINRGTDALIGG---------KKVLICGYGDVGKGCAEAMKGQGARVS 302 Query: 199 IVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKD-GVAQE 257 + E P ++ + G ++T E+I D VT T KD + + Sbjct: 303 VTEIDP----------INALQAMME--GFDVVTVE--EAIGDADIVVTATGNKDIIMLEH 348 Query: 258 LKA--EKVLQA-IGFAPN-VEGYGLDKAGVA 284 +KA + + IG N ++ GL+++G Sbjct: 349 IKAMKDHAILGNIGHFDNEIDMAGLERSGAT 379 >5U4H-A nrPDB Length = 421 Score = 29.5 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 15/109 (13%), Positives = 29/109 (26%), Gaps = 15/109 (13%) Query: 364 QARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDV------- 416 +A +V T + + G +V +L + V Sbjct: 134 EALGAHIEVENGYVHATVDGRLKGG---EVVFDMVTVGGTENILMAAALADGVTTIRNAA 190 Query: 417 --AELLPELTLAQRWDLTASELA-RNVHTHPTMSEALQECFHGLVGHMI 462 E+ + + L + T E+L C + +V I Sbjct: 191 REPEITDLAQMLIKMGAKIEGLDTDTLVV--TGVESLHGCEYAVVADRI 237 >1PJ5-A nrPDB Length = 830 Score = 29.5 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 19/38 (50%), Gaps = 1/38 (2%) Query: 173 SIIIAGAGAIGMEFGYVLKNYG-VDVTIVEFLPRALPN 209 I+I GAG +G L G ++T+++ P +P Sbjct: 6 RIVIIGAGIVGTNLADELVTRGWNNITVLDQGPLNMPG 43 >3KYD-B nrPDB Length = 551 Score = 29.5 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 15/32 (46%), Gaps = 1/32 (3%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYG-VDVTIVEF 202 +++ GAG IG E L G + +++ Sbjct: 20 GRVLVVGAGGIGCELLKNLVLTGFSHIDLIDL 51 >1XJ5-A nrPDB Length = 334 Score = 29.5 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 29/168 (17%), Positives = 59/168 (35%), Gaps = 32/168 (19%) Query: 111 GYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSREL 170 G +L + + F + AT ++ G +T ++ +E+ Sbjct: 57 GEAHSLKVEKVLFQGKSDYQDVIVFQS---ATYGKVLVLDGVIQ----LTERDECAYQEM 109 Query: 171 -----------PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKE-- 217 PK +++ G G G VL+ +I + + DVSK+ Sbjct: 110 ITHLPLCSIPNPKKVLVIGGGD-----GGVLREVARHASIEQIDMCEIDKMVVDVSKQFF 164 Query: 218 --IEKQFKKLGVTILTATKV---ESIADGGSQVTVTVTKD--GVAQEL 258 + ++ V ++ V ++ A+G + + D G A+EL Sbjct: 165 PDVAIGYEDPRVNLVIGDGVAFLKNAAEGSYDAVIVDSSDPIGPAKEL 212 >1A17-A nrPDB Length = 166 Score = 29.5 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 24/72 (33%), Gaps = 7/72 (9%) Query: 283 VALTDRKAIGVD----DYMRTNVGHIYAIGDVNGLLQLAHVAEAQ--GVVAAETIAGAET 336 + L AI Y+RT YA+GD ++L A+ G Sbjct: 40 IELNPSNAIYYGNRSLAYLRTECYG-YALGDATRAIELDKKYIKGYYRRAASNMALGKFR 98 Query: 337 LTLGDHRMLPRA 348 L D+ + + Sbjct: 99 AALRDYETVVKV 110 >3KYC-B nrPDB Length = 660 Score = 29.5 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 15/32 (46%), Gaps = 1/32 (3%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYG-VDVTIVEF 202 +++ GAG IG E L G + +++ Sbjct: 38 GRVLVVGAGGIGCELLKNLVLTGFSHIDLIDL 69 >4PRK-A nrPDB Length = 336 Score = 29.1 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 20/47 (42%), Gaps = 1/47 (2%) Query: 152 TSLSANVVTYEEQILSREL-PKSIIIAGAGAIGMEFGYVLKNYGVDV 197 ++ T + ++S E+ K+I + G G IG + G V Sbjct: 126 ANMDKGDFTNPDSLISNEIYNKTIGLIGVGHIGSAVAQIFSAMGAKV 172 >3AOE-E nrPDB Length = 419 Score = 29.1 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 24/160 (15%), Positives = 50/160 (31%), Gaps = 16/160 (10%) Query: 144 SSTRLVPGTSLSANVVTYEEQILSRELPKS---------IIIAGAGAIGMEFGYVLKNYG 194 + G+ + ++ L K +++ G G +G + G Sbjct: 182 GKPHALGGSEGRDDAAGLGALLVLEALAKRRGLDLRGARVVVQGLGQVGAAVALHAERLG 241 Query: 195 VDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGV 254 + V V + + E+ ++ G E + ++V V ++G Sbjct: 242 MRVVAVATSMGGMYAPEGLDVAEVLSAYEATGSLPRLDLAPEEVFGLEAEVLVLAAREGA 301 Query: 255 AQELKAEKV-------LQAIGFAPNVEGYGLDKAGVALTD 287 +A +V + G P E Y L K + + D Sbjct: 302 LDGDRARQVQAQAVVEVANFGLNPEAEAYLLGKGALVVPD 341 >4X4J-A nrPDB Length = 507 Score = 29.1 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 19/31 (61%) Query: 174 IIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP 204 ++IAGAG G+ L+ G+ V ++E LP Sbjct: 25 VVIAGAGPAGLMLAGELRLAGIGVVVLERLP 55 Score = 28.3 bits (62), Expect = 7.3, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 15/29 (51%) Query: 6 VVVLGAGPGGYVAAIRAAQLGLSTAIVEP 34 VV+ GAGP G + A G+ ++E Sbjct: 25 VVIAGAGPAGLMLAGELRLAGIGVVVLER 53 >2EW2-A nrPDB Length = 316 Score = 29.1 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDVTIVE 201 I IAGAGA+G G +L G DVT+++ Sbjct: 5 KIAIAGAGAMGSRLGIMLHQGGNDVTLID 33 >3SM8-A nrPDB Length = 381 Score = 29.1 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 14/32 (43%), Gaps = 1/32 (3%) Query: 5 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY 36 D +V+GAG G + G ++E + Sbjct: 11 DYLVIGAGIAGASTGYWLSAHG-RVVVLEREA 41 >4NV4-A nrPDB Length = 176 Score = 29.1 bits (64), Expect = 4.7, Method: Composition-based stats. Identities = 12/90 (13%), Positives = 35/90 (38%) Query: 47 IPSKALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKI 106 + K+++ + ++ + ++ + FD + + ++ R+ G+ + K Sbjct: 25 VEGKSMMPTLQDGNMLVVNKVSYHVGDLNRFDVVVFHANKKEDYVKRIIGLPGDHIEYKH 84 Query: 107 TEIHGYGTFADANTLLVDLNDGGTESVTFD 136 +++ G F D L + +T D Sbjct: 85 DKLYVNGQFVDEPYLETYKKEIDGRQLTGD 114 >2QK4-A nrPDB Length = 452 Score = 28.7 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 18/37 (48%), Gaps = 1/37 (2%) Query: 6 VVVLGAGPGGYVAAIRAAQ-LGLSTAIVEPKYWGGVC 41 V+++G+G + A + AQ + +V P G C Sbjct: 27 VLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTAC 63 >4G65-A nrPDB Length = 461 Score = 28.7 bits (63), Expect = 5.2, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 48/137 (35%), Gaps = 14/137 (10%) Query: 162 EEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEI--- 218 E + + I+I G G IG L+ V ++E + ++ I Sbjct: 226 SELQRLEKPYRRIMIVGGGNIGASLAKRLEQT-YSVKLIERNLQRAEKLSEELENTIVFC 284 Query: 219 -----EKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNV 273 ++ + + + + D + ++ + K + A+KV+ I V Sbjct: 285 GDAADQELLTEENIDQVDVFIALTNEDETNIMSAMLAK-----RMGAKKVMVLIQRGAYV 339 Query: 274 EGYGLDKAGVALTDRKA 290 + VA++ ++A Sbjct: 340 DLVQGGVIDVAISPQQA 356 >6F73-A nrPDB Length = 574 Score = 28.7 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 35/99 (35%), Gaps = 15/99 (15%) Query: 9 LGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKA 68 LGAG G+ A A G GG C VG + ++ + + Sbjct: 197 LGAGVEGFEAYAMANSTGHRIV-------GGTCPTVGIVGGYTQGGGHSIL------SSS 243 Query: 69 FGISGEVTFDYGIAYDRSRKVA--EGRVAGVHFLMKKNK 105 +G++ + ++ + R + R + +++ + Sbjct: 244 YGVAADNVLEWEVVTADGRHLVATPTRNSDLYWALSGGG 282 >5YL7-A nrPDB Length = 347 Score = 28.7 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 39/189 (20%), Positives = 63/189 (33%), Gaps = 24/189 (12%) Query: 11 AGPGGYVAAIRAAQ-LGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI---FTKDA 66 AG A A G+ A+++ Y LN +P ++ N + + DA Sbjct: 18 AGGLNLPTAWDTATGSGVVVAVLDTGYRPHADLNANILPGYDMISNLSVANDGGGRDSDA 77 Query: 67 KAFG---ISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLV 123 + G + E + G VA V N + G A + V Sbjct: 78 RDPGDAVAANECGTNGAQNSSWHGTHVAGTVAAV-----TNNGEGVAGVAYNAKVVPVRV 132 Query: 124 DLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV------------TYEEQILSRELP 171 GG S D I A+G S +P S A+V+ T + I + Sbjct: 133 LGKCGGLTSDIADGIIWASGGSVSGIPANSNPADVINMSLGGSGSCSSTTQNAINTARSN 192 Query: 172 KSIIIAGAG 180 ++++ AG Sbjct: 193 GTVVVIAAG 201 >4UEJ-A nrPDB Length = 346 Score = 28.7 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 37/112 (33%), Gaps = 23/112 (20%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVD-VTIVEFLPRALPNEDADVSKEIEKQFKKLGVTIL 230 K++II GAG IG+ G VT ++ L + K F + Sbjct: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLA---------LAKSFGAM----- 207 Query: 231 TATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAG 282 S Q+ + +EL+ +++ P ++ AG Sbjct: 208 --QTFNSSEMSAPQMQSVL------RELRFNQLILETAGVPQTVELAVEIAG 251 >3LLV-A nrPDB Length = 141 Score = 28.7 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 6/33 (18%), Positives = 11/33 (33%) Query: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKY 36 Y+ +V+G+ G G V+ Sbjct: 7 YEYIVIGSEAAGVGLVRELTAAGKKVLAVDKSK 39 >2X3N-A nrPDB Length = 399 Score = 28.7 bits (63), Expect = 5.9, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 16/31 (51%) Query: 3 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVE 33 H DV++ G G GG + A + G +VE Sbjct: 6 HIDVLINGCGIGGAMLAYLLGRQGHRVVVVE 36 >3QY6-A nrPDB Length = 262 Score = 28.7 bits (63), Expect = 6.0, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 17/43 (39%), Gaps = 3/43 (6%) Query: 307 IGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRAT 349 GD +++A A QG+ TI G ++ P A Sbjct: 16 AGDSADSIEMARAAVRQGI---RTIIATPHHNNGVYKNEPAAV 55 >3HM2-A nrPDB Length = 178 Score = 28.7 bits (63), Expect = 6.1, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 15/51 (29%) Query: 5 DVVVLGAG---PGGYVAAIR----AAQLGLSTAIVE--------PKYWGGV 40 DV+ +G G PG + AA + +L + VE K +GG Sbjct: 96 DVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAVTVESEQMLWALRKQFGGT 146 >4CJX-A nrPDB Length = 319 Score = 28.7 bits (63), Expect = 6.1, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 16/31 (51%), Gaps = 1/31 (3%) Query: 172 KSIIIAGAGAI-GMEFGYVLKNYGVDVTIVE 201 K +++ G G I G+ +L N VT+V Sbjct: 185 KRVVVLGRGDIAGLPVATLLANEDATVTVVH 215 >1YOV-B nrPDB Length = 444 Score = 28.7 bits (63), Expect = 6.2, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 20/54 (37%), Gaps = 3/54 (5%) Query: 150 PGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYG-VDVTIVEF 202 P T T Q L +++ GAG +G E L G + +++ Sbjct: 31 PFTHPDFEPSTESLQFLLDTC--KVLVIGAGGLGCELLKNLALSGFRQIHVIDM 82 >1UIR-A nrPDB Length = 314 Score = 28.3 bits (62), Expect = 6.4, Method: Composition-based stats. Identities = 9/54 (16%), Positives = 21/54 (38%), Gaps = 8/54 (14%) Query: 171 PKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKK 224 PK ++I G G G L+ T+ + + D ++ + ++ + Sbjct: 78 PKRVLIVGGG-----EGATLREVLKHPTV---EKAVMVDIDGELVEVAKRHMPE 123 >2CDC-A nrPDB Length = 366 Score = 28.3 bits (62), Expect = 6.6, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 18/33 (54%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLP 204 + +++ G G IG+ F + + YG++V + Sbjct: 182 RKVLVVGTGPIGVLFTLLFRTYGLEVWMANRRE 214 >3E2V-A nrPDB Length = 401 Score = 28.3 bits (62), Expect = 6.7, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 24/85 (28%), Gaps = 12/85 (14%) Query: 380 TANAKAHGVGD---PSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASEL 436 G P+ +VKL+ A + + G +AE A + +L Sbjct: 23 DPMFHGIYNGKQYHPADYVKLLERAAQRHVKNALVTGSSIAESQS----AIELVSSVKDL 78 Query: 437 -----ARNVHTHPTMSEALQECFHG 456 + HP + G Sbjct: 79 SPLKLYHTIGVHPCCVNEFADASQG 103 >2NVU-B nrPDB Length = 805 Score = 28.3 bits (62), Expect = 7.0, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 20/54 (37%), Gaps = 3/54 (5%) Query: 150 PGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYG-VDVTIVEF 202 P T T Q L +++ GAG +G E L G + +++ Sbjct: 392 PFTHPDFEPSTESLQFLLDTC--KVLVIGAGGLGCELLKNLALSGFRQIHVIDM 443 >6APH-A nrPDB Length = 445 Score = 28.3 bits (62), Expect = 7.3, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 32/99 (32%), Gaps = 12/99 (12%) Query: 172 KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILT 231 K +++ G G +G + G VT+ E P + +E K T++ Sbjct: 227 KRVVVCGFGDVGKGTAASFRGAGSIVTVTEIDPIC------ALQAAMEGYEVKQLDTVVD 280 Query: 232 ATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQA-IGF 269 + G + G E +K + IG Sbjct: 281 NADIIITTTGNFGIVR-----GEHFEKMKDKTIVCNIGH 314 >3OJO-A nrPDB Length = 431 Score = 28.3 bits (62), Expect = 7.8, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 13/25 (52%) Query: 173 SIIIAGAGAIGMEFGYVLKNYGVDV 197 + + G G IG+ + +GVDV Sbjct: 13 KLTVVGLGYIGLPTSIMFAKHGVDV 37 >1M9N-A nrPDB Length = 613 Score = 27.9 bits (61), Expect = 9.8, Method: Composition-based stats. Identities = 22/167 (13%), Positives = 41/167 (24%), Gaps = 45/167 (26%) Query: 309 DVNGLLQLA-------HVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPN----VAS 357 D+ G ++ H A G++A + D ++ V+S Sbjct: 74 DLTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMNKQDFSLVRVVVCNLYPFVKTVSS 133 Query: 358 FGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVA 417 G+T +A V K A V +V D Sbjct: 134 PGVTVPEA--------VEKIDIGGVALLRAAAKNHARVTVVCDPAD-------------- 171 Query: 418 ELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 464 ++A+ + + T E + H + Sbjct: 172 ----YSSVAKEMAASKDK--------DTSVETRRHLALKAFTHTAQY 206 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.150 0.422 Lambda K H 0.267 0.0460 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,992,844 Number of Sequences: 36641 Number of extensions: 850698 Number of successful extensions: 5275 Number of sequences better than 10.0: 397 Number of HSP's better than 10.0 without gapping: 430 Number of HSP's successfully gapped in prelim test: 136 Number of HSP's that attempted gapping in prelim test: 3495 Number of HSP's gapped (non-prelim): 970 length of query: 464 length of database: 10,336,785 effective HSP length: 100 effective length of query: 364 effective length of database: 6,672,685 effective search space: 2428857340 effective search space used: 2428857340 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (27.9 bits)