BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P97784 (606 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4K0R-A nrPDB 1263 0.0 4I6J-A nrPDB 888 0.0 3FY4-A nrPDB 515 e-146 4JZY-A nrPDB 374 e-104 1OWP-A nrPDB 191 6e-49 4U63-A nrPDB 172 4e-43 1NP7-A nrPDB 163 2e-40 1U3C-A nrPDB 152 3e-37 2VTB-B nrPDB 147 1e-35 1DNP-A nrPDB 139 4e-33 2E0I-A nrPDB 139 5e-33 2J08-A nrPDB 94 2e-19 5O8D-A nrPDB 40 0.002 3S9V-A nrPDB 33 0.43 1W6K-A nrPDB 31 1.5 3QR1-A nrPDB 30 3.2 4A5V-A nrPDB 30 4.1 3QR0-A nrPDB 28 9.2 >4K0R-A nrPDB Length = 617 Score = 1263 bits (3268), Expect = 0.0, Method: Compositional matrix adjust. Identities = 606/606 (100%), Positives = 606/606 (100%) Query: 1 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE 60 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE Sbjct: 1 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE 60 Query: 61 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA 120 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA Sbjct: 61 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA 120 Query: 121 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMT 180 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMT Sbjct: 121 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMT 180 Query: 181 PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMN 240 PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMN Sbjct: 181 PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMN 240 Query: 241 ANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA 300 ANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA Sbjct: 241 ANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA 300 Query: 301 TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA 360 TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA Sbjct: 301 TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA 360 Query: 361 VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR 420 VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR Sbjct: 361 VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR 420 Query: 421 RTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN 480 RTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN Sbjct: 421 RTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN 480 Query: 481 IERMKQIYQQLSRYRGLGLLASVPSNSNGNGGLMGYAPGENVPSCSSSGNGGLMGYAPGE 540 IERMKQIYQQLSRYRGLGLLASVPSNSNGNGGLMGYAPGENVPSCSSSGNGGLMGYAPGE Sbjct: 481 IERMKQIYQQLSRYRGLGLLASVPSNSNGNGGLMGYAPGENVPSCSSSGNGGLMGYAPGE 540 Query: 541 NVPSCSGGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGTGLSSGKRPSQEEDAQSVGPKV 600 NVPSCSGGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGTGLSSGKRPSQEEDAQSVGPKV Sbjct: 541 NVPSCSGGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGTGLSSGKRPSQEEDAQSVGPKV 600 Query: 601 QRQSSN 606 QRQSSN Sbjct: 601 QRQSSN 606 >4I6J-A nrPDB Length = 544 Score = 888 bits (2294), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/504 (80%), Positives = 460/504 (91%) Query: 2 GVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLED 61 G ++VHWFRKGLRLHDNPAL ++GA +RCVYILDPWFA SS+VGINRWRFLLQ LED Sbjct: 20 GASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLED 79 Query: 62 LDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAG 121 LD +LRKLNSRLFV+RGQPADVFPRLFKEW +T+L+ EYDSEPFGKERDAAI K+A EAG Sbjct: 80 LDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAG 139 Query: 122 VEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTP 181 VEV+ SHTLYDLD+IIELNG +PPLTYKRFQ L+S+ME + PA ++S + C Sbjct: 140 VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAE 199 Query: 182 LSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNA 241 + ++HD+ YGVPSLEELGF T+GL AVW GGETEAL RL++HLERKAWVAN+ERPRMNA Sbjct: 200 IQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNA 259 Query: 242 NSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAAT 301 NSLLASPTGLSPYLRFGCLSCRLFY++L DLYKKVK+NS+PPLSL+GQLLWREFFYTAAT Sbjct: 260 NSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAAT 319 Query: 302 NNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAV 361 NNPRFD+MEGNPIC+QIPWD+NPEALAKWAEG+TGFPWIDAIMTQLRQEGWIHHLARHAV Sbjct: 320 NNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAV 379 Query: 362 ACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRR 421 ACFLTRGDLW+SWE G++VF+ELLLDAD+S+NAGSWMWLSCS+FFQQFFHCYCPVGFGRR Sbjct: 380 ACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRR 439 Query: 422 TDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNI 481 TDP+GDYIRRYLP L+GFP++YIY+PWNAPE +QK AKC+IGV+YP+P+VNHAE SRLNI Sbjct: 440 TDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNI 499 Query: 482 ERMKQIYQQLSRYRGLGLLASVPS 505 ERMKQIYQQLSRYRGL LLASVPS Sbjct: 500 ERMKQIYQQLSRYRGLCLLASVPS 523 >3FY4-A nrPDB Length = 537 Score = 515 bits (1327), Expect = e-146, Method: Compositional matrix adjust. Identities = 252/501 (50%), Positives = 342/501 (68%), Gaps = 21/501 (4%) Query: 2 GVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFA---------GSSNVGINRW 52 G ++ WFRKGLR+HDNPAL+ +G++ + V+++DP + GSS G+NR Sbjct: 4 GSGSLIWFRKGLRVHDNPALEYASKGSEFMYPVFVIDPHYMESDPSAFSPGSSRAGVNRI 63 Query: 53 RFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAA 112 RFLL+ L+DLD++L+KL SRL V +G+P +V R +EW + +L EYD++P+ + D Sbjct: 64 RFLLESLKDLDSSLKKLGSRLLVFKGEPGEVLVRCLQEWKVKRLCFEYDTDPYYQALDVK 123 Query: 113 IKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITS 172 +K A+ GVEV +SHTL++ IIE NGG+PPL+Y+ F + EP ++ + S Sbjct: 124 VKDYASSTGVEVFSPVSHTLFNPAHIIEKNGGKPPLSYQSFLKVAG--EPSCAKSELVMS 181 Query: 173 DVIGKCMTPLSDDHDEKYG-VPSLEELGFDTDGLSSAVWP---GGETEALTRLERHLERK 228 + P+ D + VPSLEELG+ D A W GGE+EAL RL + + K Sbjct: 182 ---YSSLPPIGDIGNLGISEVPSLEELGYKDD--EQADWTPFRGGESEALKRLTKSISDK 236 Query: 229 AWVANFERPRMNANSLLA-SPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLY 287 AWVANFE+P+ + ++ L + T +SPYL+FGCLS R FY L ++YK VKK++SPP+SL Sbjct: 237 AWVANFEKPKGDPSAFLKPATTVMSPYLKFGCLSSRYFYQCLQNIYKDVKKHTSPPVSLL 296 Query: 288 GQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQL 347 GQLLWREFFYT A P FDKM+GN IC QIPW+++ LA W +G+TG+PWIDAIM QL Sbjct: 297 GQLLWREFFYTTAFGTPNFDKMKGNRICKQIPWNEDHAMLAAWRDGKTGYPWIDAIMVQL 356 Query: 348 RQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQ 407 + GW+HHLARH VACFLTRGDL+I WE+G VFE LL+D+DW+IN G+WMWLSCSSFF Sbjct: 357 LKWGWMHHLARHCVACFLTRGDLFIHWEQGRDVFERLLIDSDWAINNGNWMWLSCSSFFY 416 Query: 408 QFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYP 467 QF Y P+ FG++ DP+G YIR +LPVL+ P +YIY+PW AP +Q A C++G +YP Sbjct: 417 QFNRIYSPISFGKKYDPDGKYIRHFLPVLKDMPKQYIYEPWTAPLSVQTKANCIVGKDYP 476 Query: 468 KPMVNHAEASRLNIERMKQIY 488 KPMV H AS+ +M + Y Sbjct: 477 KPMVLHDSASKECKRKMGEAY 497 >4JZY-A nrPDB Length = 536 Score = 374 bits (961), Expect = e-104, Method: Compositional matrix adjust. Identities = 211/516 (40%), Positives = 295/516 (57%), Gaps = 35/516 (6%) Query: 2 GVNAVHWFRKGLRLHDNPALKECIQGAD---TIRCVYILDPWFAGSSNVGINRWRFLLQC 58 G N + WFR GLRLHDNPAL + D + V+I D AG+ NVG NR RFLL Sbjct: 6 GANVI-WFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDS 64 Query: 59 LEDLDANLRKLNS---RLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKK 115 L+D+D L+ RL V G+PA +F RL ++ + ++ IE D EP ERD +I+ Sbjct: 65 LQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRS 124 Query: 116 LATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKM-EPLEMPADTITSDV 174 L E ++ + ++SHTL+D +IE NGG PPLTY+ F V + P AD D Sbjct: 125 LCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDA 184 Query: 175 IGKCMTPL------------SDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLE 222 + P + +H YG + +GF L+ W GGET+AL L+ Sbjct: 185 TFVELDPEFCRSLKLFEQLPTPEHFNVYG----DNMGF----LAKINWRGGETQALLLLD 236 Query: 223 RHL--ERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVK--K 278 L E+ A+ F P ++ SP +S +LRFGCLS R FY+ + DL+K V+ Sbjct: 237 ERLKVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLGV 296 Query: 279 NSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDK-NPEALAKWAEGRTGF 337 + + GQL+WRE+FYT + NNP +D+MEGN IC+ IPW K N L W G+TGF Sbjct: 297 QMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGF 356 Query: 338 PWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSW 397 P ID M QL EGW+HH R+ VA FLTRG LW SWE G++ F + LLDADWS+ AG+W Sbjct: 357 PLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNW 416 Query: 398 MWLSCSSFFQQFFHCY--CPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQ 455 MW+S S+F + CPV +R DP+G YI++Y+P L P +++++PW Q Sbjct: 417 MWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQ 476 Query: 456 KVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQL 491 + +CLIGV+YP+ +++ + A + N+ MK + L Sbjct: 477 EQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSL 512 >1OWP-A nrPDB Length = 484 Score = 191 bits (486), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 138/494 (27%), Positives = 234/494 (47%), Gaps = 26/494 (5%) Query: 1 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE 60 M + W R+ LRL DN L + + ++ LDP S+++ R +L CL+ Sbjct: 1 MAAPILFWHRRDLRLSDNIGLAAARAQSAQLIGLFCLDPQILQSADMAPARVAYLQGCLQ 60 Query: 61 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA 120 +L ++ SRL +++G P + P+L ++ + D EP+G++RD + A Sbjct: 61 ELQQRYQQAGSRLLLLQGDPQHLIPQLAQQLQAEAVYWNQDIEPYGRDRDGQVAAALKTA 120 Query: 121 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRF-QTLVSKMEPLEMPADTITSDVIGKCM 179 G+ + L+ D+I+ G P Y F + ++ +P + T D+ + + Sbjct: 121 GIRAVQLWDQLLHSPDQILS-GSGNPYSVYGPFWKNWQAQPKPTPVATPTELVDLSPEQL 179 Query: 180 TPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRM 239 T ++ + +P+L++LGFD DG V P GET A+ RL+ +R +A+++ P+ Sbjct: 180 TAIAPLLLSE--LPTLKQLGFDWDG-GFPVEP-GETAAIARLQEFCDRA--IADYD-PQR 232 Query: 240 NANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSP-PLSLYGQ-LLWREFFY 297 N + A +GLSP L+FG + R + + + + + + + ++ Q L WREF+ Sbjct: 233 NFPA-EAGTSGLSPALKFGAIGIRQAWQAASAAHALSRSDEARNSIRVWQQELAWREFYQ 291 Query: 298 TAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLA 357 A + P + Q PW+ W + +TG+P +DA M QL + GW+H+ Sbjct: 292 HALYHFPSLADGPYRSLWQQFPWENREALFTAWTQAQTGYPIVDAAMRQLTETGWMHNRC 351 Query: 358 RHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVG 417 R VA FLT+ DL I W G + F + L+D D + N G W W + S + + P Sbjct: 352 RMIVASFLTK-DLIIDWRRGEQFFMQHLVDGDLAANNGGWQWSASSGMDPKPLRIFNPAS 410 Query: 418 FGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEAS 477 ++ D YI+R+LP LR K + I + YP P+VNH Sbjct: 411 QAKKFDATATYIKRWLPELRHVHPKDL---------ISGEITPIERRGYPAPIVNH---- 457 Query: 478 RLNIERMKQIYQQL 491 L ++ K +Y QL Sbjct: 458 NLRQKQFKALYNQL 471 >4U63-A nrPDB Length = 498 Score = 172 bits (436), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 137/474 (28%), Positives = 212/474 (44%), Gaps = 21/474 (4%) Query: 6 VHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDAN 65 + WFRK LRL DN AL ++ + VYI + + G W +L L L ++ Sbjct: 28 IVWFRKDLRLSDNLALLAAVEHGGPVIPVYIREK--SAGPLGGAQEW-WLHHSLAALSSS 84 Query: 66 LRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVI 125 L K RL + G + L E + +P G D A+K+ + G+ V Sbjct: 85 LEKAGGRLVLASGDAERILRDLISETGADTVVWNRRYDPTGMATDKALKQKLRDDGLTVR 144 Query: 126 VRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTPLSDD 185 L++ ++ +GG P Y F + + PAD S K P S+ Sbjct: 145 SFSGQLLHEPSRLQTKSGG-PYRVYTPFWRALEGSDEPHAPADPPKSLTAPKVW-PKSEK 202 Query: 186 HDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLE--RKAWVANFERPRMNANS 243 +P+ + D S +W GET AL +L+ ++ K + + P A S Sbjct: 203 LSNWKLLPTKPDWAKDF----SDIWTPGETGALDKLDDFIDGALKGYEEGRDFPAKPATS 258 Query: 244 LLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNN 303 LL SP+L G +S + L + + N +++WREF Y + Sbjct: 259 LL------SPHLAAGEISPAAVWHATKGLSRHIASNDIS--RFRKEIVWREFCYHLLFHF 310 Query: 304 PRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVAC 363 P + N W + ++ W G TG+P +DA M QL Q G +H+ R VA Sbjct: 311 PELGEKNWNDSFDAFSWRDDEKSFKAWTRGMTGYPIVDAGMRQLWQHGTMHNRVRMIVAS 370 Query: 364 FLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCS-SFFQQFFHCYCPVGFGRRT 422 FL + L I W +G K F + L+DAD + NA +W W++ S + FF + P+ G + Sbjct: 371 FLIK-HLLIDWRKGEKWFRDTLVDADPASNAANWQWVAGSGADASPFFRIFNPILQGEKF 429 Query: 423 DPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEA 476 D +GDY+RR++P L KYI+ P+ AP+ K A +G YP P+V+H +A Sbjct: 430 DGDGDYVRRFVPELEKLERKYIHKPFEAPKDALKKAGVELGKTYPLPIVDHGKA 483 >1NP7-A nrPDB Length = 489 Score = 163 bits (412), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 138/493 (27%), Positives = 225/493 (45%), Gaps = 28/493 (5%) Query: 8 WFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINR---WR--FLLQCLEDL 62 WFR LRLHD+ L ++ I VY DP ++ G + WR FL Q +++L Sbjct: 11 WFRNDLRLHDHEPLHRALKSGLAITAVYCYDPRQFAQTHQGFAKTGPWRSNFLQQSVQNL 70 Query: 63 DANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAA--IKKLATEA 120 +L+K+ ++L V G P V P++ K+ I +I Y E +E D + K T Sbjct: 71 AESLQKVGNKLLVTTGLPEQVIPQIAKQ--INAKTIYYHREVTQEELDVERNLVKQLTIL 128 Query: 121 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMT 180 G+E TL + + + P + +F+ + K + P S ++ Sbjct: 129 GIEAKGYWGSTLCHPEDL-PFSIQDLPDLFTKFRKDIEKKKISIRPCFFAPSQLL----- 182 Query: 181 PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMN 240 P + E P + D S + GGET L RL+ + + +++ R Sbjct: 183 PSPNIKLELTAPPPEFFPQINFDHRSVLAFQGGETAGLARLQDYFWHGDRLKDYKETR-- 240 Query: 241 ANSLLAS--PTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYT 298 N ++ + + SP+L GCLS R Y ++ ++ N S ++ +LLWR+FF Sbjct: 241 -NGMVGADYSSKFSPWLALGCLSPRFIYQEVKRYEQERVSNDSTHWLIF-ELLWRDFFRF 298 Query: 299 AATN--NPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHL 356 A N F++ G + PW ++ W G+TG+P +DA M +L G++ + Sbjct: 299 VAQKYGNKLFNR--GGLLNKNFPWQEDQVRFELWRSGQTGYPLVDANMRELNLTGFMSNR 356 Query: 357 ARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPV 416 R VA FL + +L I W G + FE L+D D N G+W + + + F + Sbjct: 357 GRQNVASFLCK-NLGIDWRWGAEWFESCLIDYDVCSNWGNWNYTAGIGNDARDFRYFNIP 415 Query: 417 GFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEA 476 ++ DP G Y+R +LP L+ P I+ PW QK +GV+YP+P VN ++ Sbjct: 416 KQSQQYDPQGTYLRHWLPELKNLPGDKIHQPWLLSATEQKQWGVQLGVDYPRPCVNFHQS 475 Query: 477 --SRLNIERMKQI 487 +R IE+M I Sbjct: 476 VEARRKIEQMGVI 488 >1U3C-A nrPDB Length = 509 Score = 152 bits (385), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 137/497 (27%), Positives = 222/497 (44%), Gaps = 31/497 (6%) Query: 6 VHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVG-INRWRFLLQCLEDLDA 64 + WFR+ LR+ DNPAL ++ I +++ P G + G ++RW +L L LD+ Sbjct: 15 IVWFRRDLRVEDNPALAAAVRAGPVI-ALFVWAPEEEGHYHPGRVSRW-WLKNSLAQLDS 72 Query: 65 NLRKLNSRLFVIRGQPADV-FPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVE 123 +LR L + L R + + K +++ + +P RD K + T G+ Sbjct: 73 SLRSLGTCLITKRSTDSVASLLDVVKSTGASQIFFNHLYDPLSLVRDHRAKDVLTAQGIA 132 Query: 124 VIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKM-----EPLEMPADTITSDVIGKC 178 V + LY+ ++ + G+P + F M PL P I+ DV Sbjct: 133 VRSFNADLLYEPWEVTD-ELGRPFSMFAAFWERCLSMPYDPESPLLPPKKIISGDVSKCV 191 Query: 179 MTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPR 238 PL + D + G +L + S W G+ T + L + + R Sbjct: 192 ADPLVFEDDSEKGSNALLARAW------SPGWSNGDKALTTFINGPL------LEYSKNR 239 Query: 239 MNANSLLASPTGLSPYLRFGCLSCR----LFYFKLTDLYKKVKKNSSPPLSLYGQLL-WR 293 A+S A+ + LSP+L FG +S R L K + + ++L+ + + R Sbjct: 240 RKADS--ATTSFLSPHLHFGEVSVRKVFHLVRIKQVAWANEGNEAGEESVNLFLKSIGLR 297 Query: 294 EFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWI 353 E+ + N+P + PW + W +GRTG+P +DA M +L GW+ Sbjct: 298 EYSRYISFNHPYSHERPLLGHLKFFPWAVDENYFKAWRQGRTGYPLVDAGMRELWATGWL 357 Query: 354 HHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCS-SFFQQFFHC 412 H R V+ L + W GMK F + LLDAD +A W +++ + ++F Sbjct: 358 HDRIRVVVSS-FFVKVLQLPWRWGMKYFWDTLLDADLESDALGWQYITGTLPDSREFDRI 416 Query: 413 YCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVN 472 P G + DPNG+Y+RR+LP L P +I+ PWNAPE + + A +G NYP P+V Sbjct: 417 DNPQFEGYKFDPNGEYVRRWLPELSRLPTDWIHHPWNAPESVLQAAGIELGSNYPLPIVG 476 Query: 473 HAEASRLNIERMKQIYQ 489 EA E + Q++Q Sbjct: 477 LDEAKARLHEALSQMWQ 493 >2VTB-B nrPDB Length = 525 Score = 147 bits (372), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 129/453 (28%), Positives = 209/453 (46%), Gaps = 33/453 (7%) Query: 5 AVHWFRKGLRLHDNPALKECIQGADTIRCVYILDP------WFAGSSNVGINRWRFLLQC 58 + WFR LR+ DN AL + +DTI VY LDP F G R FL++C Sbjct: 43 TILWFRNDLRVLDNDALYKAWSSSDTILPVYCLDPRLFHTTHFFNFPKTGALRGGFLMEC 102 Query: 59 LEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKL--SIEYDSEPFGKER--DAAIK 114 L DL NL K L + G+P ++ P L K++ + E SE ER + +K Sbjct: 103 LVDLRKNLMKRGLNLLIRSGKPEEILPSLAKDFGARTVFAHKETCSEEVDVERLVNQGLK 162 Query: 115 KLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDV 174 ++ +E+I T+Y D + + P Y +F+ V E +S Sbjct: 163 RVGNSTKLELI--WGSTMYHKDDL-PFDVFDLPDVYTQFRKSV------EAKCSIRSSTR 213 Query: 175 IGKCM--TPLSDDHDEKYGVPSLEELGFDTDGLSSAV-WPGGETEALTRLERHLERKAWV 231 I + TP DD + VP+LE+LG + ++ + + GGE+ + R+ + +K + Sbjct: 214 IPLSLGPTPSVDDWGD---VPTLEKLGVEPQEVTRGMRFVGGESAGVGRVFEYFWKKDLL 270 Query: 232 ANFERPRMNANSLLAS--PTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQ 289 ++ R N +L T SP+L FGC+S R Y ++ K+ N+S L+ + Sbjct: 271 KVYKETR---NGMLGPDYSTKFSPWLAFGCISPRFIYEEVQRYEKERVANNSTYWVLF-E 326 Query: 290 LLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQ 349 L+WR++F + G P V W ++ + W + +TG+P IDA M +L Sbjct: 327 LIWRDYFRFLSIKCGNSLFHLGGPRNVNGKWSQDQKLFESWRDAKTGYPLIDANMKELST 386 Query: 350 EGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQF 409 G++ + R V FL R D+ + W G + FE LLD D N G+W + + + ++ Sbjct: 387 TGFMSNRGRQIVCSFLVR-DMGLDWRMGAEWFETCLLDYDPCSNYGNWTYGAGVNDPRED 445 Query: 410 FHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAK 442 + P + DP G+Y+ +L LR P + Sbjct: 446 RYFSIPKQ-AQNYDPEGEYVAFWLQQLRRLPKE 477 >1DNP-A nrPDB Length = 471 Score = 139 bits (349), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 124/479 (25%), Positives = 202/479 (42%), Gaps = 38/479 (7%) Query: 8 WFRKGLRLHDNPALKE-CIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANL 66 WFR+ LRLHDN AL C + + +YI P + N+ + + L L L Sbjct: 6 WFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWATHNMSPRQAELINAQLNGLQIAL 65 Query: 67 RKLNSRLFVIRGQ----PADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGV 122 + L ++ ++ E ++T L Y E + RD +++ Sbjct: 66 AEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFYNYQYEVNERARDVEVERALRNVVC 125 Query: 123 EVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMT-P 181 E +D D +I G ++ ++ P + + + +C+ P Sbjct: 126 EG--------FD-DSVILPPGAVMTGNHEMYKVFT----PFKNAWLKRLREGMPECVAAP 172 Query: 182 LSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNA 241 PS+ L + +A +P E A+ +L + + A +E+ R Sbjct: 173 KVRSSGSIEPSPSIT-LNYPRQSFDTAHFPVEEKAAIAQLRQFCQNGA--GEYEQQR--D 227 Query: 242 NSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAAT 301 + + LS L G LS R +L + + + L +L+WREF+ T Sbjct: 228 FPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWL-NELIWREFYRHLIT 286 Query: 302 NNPRFDKMEGNPICV---QIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLAR 358 +P K P ++ W NP L W EG+TG+P +DA M QL GW+H+ R Sbjct: 287 YHPSLCKH--RPFIAWTDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQLNSTGWMHNRLR 344 Query: 359 HAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMW-LSCSSFFQQFFHCYCPVG 417 A FL + DL I W EG + F L+D D + N G W W S + +F + P Sbjct: 345 MITASFLVK-DLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTDAAPYFRIFNPTT 403 Query: 418 FGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEA 476 G + D G++IR++LP LR P K +++PW + K + ++YP+P+V H EA Sbjct: 404 QGEKFDHEGEFIRQWLPELRDVPGKVVHEPWKWAQ------KAGVTLDYPQPIVEHKEA 456 >2E0I-A nrPDB Length = 440 Score = 139 bits (349), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 129/483 (26%), Positives = 193/483 (39%), Gaps = 77/483 (15%) Query: 3 VNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPW----------FAGSSNVGINRW 52 ++ + FR+ LRL DN L + D + V+I DP FA S Sbjct: 1 MDCIFIFRRDLRLEDNTGLNYALSECDRVIPVFIADPRQLINNPYKSEFAVS-------- 52 Query: 53 RFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAA 112 F++ L +LD LRK SRL V G+ V R F + + + + D PF RD Sbjct: 53 -FMINSLLELDDELRKKGSRLNVFFGEAEKVVSRFFNK--VDAIYVNEDYTPFSISRDEK 109 Query: 113 IKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITS 172 I+K+ E G+E + L N + F VSK++ E + Sbjct: 110 IRKVCEENGIEFKAYEDYLLTPKSLFHHRN-------FTSFYNEVSKVKVREPETMEGSF 162 Query: 173 DVIGKCMTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVA 232 DV M + + S ++ GG E L L R+++ + Sbjct: 163 DVTDSSMNV---------------DFLLTFKKIESPLFRGGRREGLYLLHRNVDFRRR-- 205 Query: 233 NFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLW 292 + P N N LSP+L+FG +S R Y+ + V+ +L W Sbjct: 206 --DYPAENNN------YRLSPHLKFGTISMREAYYTQKGKEEFVR-----------ELYW 246 Query: 293 REFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGW 352 R+FF A NP I W+ N W EGRTG+P IDA M L G+ Sbjct: 247 RDFFTLLAYYNPHVFGHCYRREYDNISWENNESYFEAWKEGRTGYPIIDAGMRMLNSTGY 306 Query: 353 IHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHC 412 I+ R VA FL + L++ W G + F L+D D +IN G+W W++ + F Sbjct: 307 INGRVRMLVAFFLVKV-LFVDWRWGERYFATKLVDYDPAINNGNWQWIASTG-VDYMFRV 364 Query: 413 YCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVN 472 + P + DP +I+ ++ L+ P P I + K + YP P+VN Sbjct: 365 FNPWKQQEKFDPEAKFIKEWVEELKDVP----------PSIIHSIYKTKVP-GYPSPIVN 413 Query: 473 HAE 475 E Sbjct: 414 WLE 416 >2J08-A nrPDB Length = 420 Score = 94.0 bits (232), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 66/223 (29%), Positives = 98/223 (43%), Gaps = 12/223 (5%) Query: 213 GETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDL 272 GE AL L LE K ER R++ + LSPY G LS RL Sbjct: 178 GEEAALAGLRAFLEAKLPRYAEERDRLDGEG----GSRLSPYFALGVLSPRL------AA 227 Query: 273 YKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAE 332 ++ ++ +LLWR+F Y + P + +P PW ++ W E Sbjct: 228 WEAERRGGEGARKWVAELLWRDFSYHLLYHFPWMAERPLDPRFQAFPWQEDEALFQAWYE 287 Query: 333 GRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSI 392 G+TG P +DA M +L G++ + AR A F + L + W+ + F LLLD D ++ Sbjct: 288 GKTGVPLVDAAMRELHATGFLSNRARMNAAQFAVK-HLLLPWKRCEEAFRHLLLDGDRAV 346 Query: 393 NAGSWMWLSCSSF-FQQFFHCYCPVGFGRRTDPNGDYIRRYLP 434 N W W +F + PV G R DP G +++R+ P Sbjct: 347 NLQGWQWAGGLGVDAAPYFRVFNPVLQGERHDPEGRWLKRWAP 389 Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 4/108 (3%) Query: 8 WFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLR 67 W R LRLHD+PAL E + + V +LDP + R + L+ + L R Sbjct: 7 WHRGDLRLHDHPALLEALARGPVVGLV-VLDP---NNLKTTPRRRAWFLENVRALREAYR 62 Query: 68 KLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKK 115 L+V+ G P + P + + P+G+ RD +++ Sbjct: 63 ARGGALWVLEGLPWEKVPEAARRLKAKAVYALTSHTPYGRYRDGRVRE 110 >5O8D-A nrPDB Length = 484 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 7/100 (7%) Query: 5 AVHWFRKGLRLHDNPAL---KECIQGADT-IRCVYILDPWFAGSSNVGINRWRFLLQCLE 60 V+W + R DN AL + + A+ + V+ L F GI ++ F+L+ L+ Sbjct: 41 VVYWMSRDQRAEDNWALLFSRAIAKEANVPVVVVFCLTDEFL---EAGIRQYEFMLKGLQ 97 Query: 61 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEY 100 +L+ +L + F +RG P + R K++N L ++ Sbjct: 98 ELEVSLSRKKIPSFFLRGDPGEKISRFVKDYNAGTLVTDF 137 Score = 29.3 bits (64), Expect = 5.4, Method: Compositional matrix adjust. Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 12/118 (10%) Query: 249 TGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQ-LLWREFFYTAATNNPRFD 307 + LSPYL FG +S + ++ +K + N + + L+W+E NP +D Sbjct: 285 SNLSPYLHFGQISSQRVVLEV----EKAESNPGSKKAFLDEILIWKEISDNFCYYNPGYD 340 Query: 308 KMEGNPICVQIPWDKNPE-------ALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLAR 358 E P + + + L ++ G+T P +A +L G +H R Sbjct: 341 GFESFPSWAKESLNAHRNDVRSHIFTLEEFEAGKTHDPLWNASQMELLSTGKMHGYTR 398 >3S9V-A nrPDB Length = 785 Score = 32.7 bits (73), Expect = 0.43, Method: Compositional matrix adjust. Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 16/117 (13%) Query: 30 TIRCVYILDPWFAGSSNV--GINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRL 87 T+ C+ L W G + V GI +R +ED + R + VFP + Sbjct: 108 TLACIITLTLWRTGETQVQKGIEFFRTQAGKMEDEADSHRPSGFEI---------VFPAM 158 Query: 88 FKEWNITKLSIEYDSEPFGKE----RDAAIKKLATEAGVEVIVRISHTLYDLDKIIE 140 KE I L + YD PF K+ R+A +K++ T+ + + ++L L +I++ Sbjct: 159 LKEAKILGLDLPYDL-PFLKQIIEKREAKLKRIPTDVLYALPTTLLYSLEGLQEIVD 214 >1W6K-A nrPDB Length = 732 Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust. Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 9/132 (6%) Query: 368 GDLWI------SWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRR 421 G W+ SWE +F E+ L DW+ S +W C + +CY V Sbjct: 193 GKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYA-VRLSAA 251 Query: 422 TDPNGDYIRRYLPVLRGFPAKYIYDPWN-APEGIQKVAKCLIGVNYP-KPMVNHAEASRL 479 DP +R+ L V ++ N AP+ + L+ V Y + H ++ L Sbjct: 252 EDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALLNLYEHHHSAHL 311 Query: 480 NIERMKQIYQQL 491 ++++Y+ + Sbjct: 312 RQRAVQKLYEHI 323 >3QR1-A nrPDB Length = 813 Score = 30.0 bits (66), Expect = 3.2, Method: Compositional matrix adjust. Identities = 12/25 (48%), Positives = 16/25 (64%) Query: 365 LTRGDLWISWEEGMKVFEELLLDAD 389 L +GD ++ WEEG F E+LL D Sbjct: 22 LIKGDKFLKWEEGSSSFTEILLRVD 46 >4A5V-A nrPDB Length = 161 Score = 29.6 bits (65), Expect = 4.1, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 5/73 (6%) Query: 524 SCSSSGNGGLMGYAPGENVPSCS----GGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGT 579 SC S N G GE VP S C G H+ + D + +K+G+ Sbjct: 10 SCVHSDNKGSRAPTIGEPVPDVSLEQCAAQCKAVDGCTHFTYNDDSKMCHVKEGKPDL-Y 68 Query: 580 GLSSGKRPSQEED 592 L+ GK S+ D Sbjct: 69 DLTGGKTASRSCD 81 >3QR0-A nrPDB Length = 816 Score = 28.5 bits (62), Expect = 9.2, Method: Compositional matrix adjust. Identities = 12/25 (48%), Positives = 16/25 (64%) Query: 365 LTRGDLWISWEEGMKVFEELLLDAD 389 L +GD ++ WEEG F E+LL D Sbjct: 22 LIKGDKFLKWEEGSSGFIEILLRVD 46 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4K0R-A nrPDB 964 0.0 4I6J-A nrPDB 726 0.0 3FY4-A nrPDB 617 e-177 4JZY-A nrPDB 569 e-163 1NP7-A nrPDB 554 e-158 4U63-A nrPDB 537 e-153 1OWP-A nrPDB 521 e-148 1U3C-A nrPDB 498 e-141 1DNP-A nrPDB 492 e-139 2E0I-A nrPDB 484 e-137 2VTB-B nrPDB 483 e-136 2J08-A nrPDB 373 e-103 Sequences not found previously or not previously below threshold: 5O8D-A nrPDB 121 1e-27 3UMV-A nrPDB 71 1e-12 3ZXS-A nrPDB 62 6e-10 5GAM-A nrPDB 37 0.025 5M99-B nrPDB 35 0.12 2X0P-A nrPDB 34 0.21 2B81-A nrPDB 33 0.39 6D97-A nrPDB 33 0.43 6ES9-A nrPDB 32 0.83 3LGB-A nrPDB 31 1.4 3QR1-A nrPDB 30 2.7 4CRV-B nrPDB 30 4.0 5IDU-A nrPDB 30 4.2 5GSM-A nrPDB 29 4.2 1FZ4-C nrPDB 29 4.3 1KB0-A nrPDB 29 4.7 >4K0R-A nrPDB Length = 617 Score = 964 bits (2491), Expect = 0.0, Method: Composition-based stats. Identities = 606/606 (100%), Positives = 606/606 (100%) Query: 1 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE 60 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE Sbjct: 1 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE 60 Query: 61 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA 120 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA Sbjct: 61 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA 120 Query: 121 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMT 180 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMT Sbjct: 121 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMT 180 Query: 181 PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMN 240 PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMN Sbjct: 181 PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMN 240 Query: 241 ANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA 300 ANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA Sbjct: 241 ANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA 300 Query: 301 TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA 360 TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA Sbjct: 301 TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA 360 Query: 361 VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR 420 VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR Sbjct: 361 VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR 420 Query: 421 RTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN 480 RTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN Sbjct: 421 RTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN 480 Query: 481 IERMKQIYQQLSRYRGLGLLASVPSNSNGNGGLMGYAPGENVPSCSSSGNGGLMGYAPGE 540 IERMKQIYQQLSRYRGLGLLASVPSNSNGNGGLMGYAPGENVPSCSSSGNGGLMGYAPGE Sbjct: 481 IERMKQIYQQLSRYRGLGLLASVPSNSNGNGGLMGYAPGENVPSCSSSGNGGLMGYAPGE 540 Query: 541 NVPSCSGGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGTGLSSGKRPSQEEDAQSVGPKV 600 NVPSCSGGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGTGLSSGKRPSQEEDAQSVGPKV Sbjct: 541 NVPSCSGGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGTGLSSGKRPSQEEDAQSVGPKV 600 Query: 601 QRQSSN 606 QRQSSN Sbjct: 601 QRQSSN 606 >4I6J-A nrPDB Length = 544 Score = 726 bits (1873), Expect = 0.0, Method: Composition-based stats. Identities = 405/504 (80%), Positives = 460/504 (91%) Query: 2 GVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLED 61 G ++VHWFRKGLRLHDNPAL ++GA +RCVYILDPWFA SS+VGINRWRFLLQ LED Sbjct: 20 GASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLED 79 Query: 62 LDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAG 121 LD +LRKLNSRLFV+RGQPADVFPRLFKEW +T+L+ EYDSEPFGKERDAAI K+A EAG Sbjct: 80 LDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAG 139 Query: 122 VEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTP 181 VEV+ SHTLYDLD+IIELNG +PPLTYKRFQ L+S+ME + PA ++S + C Sbjct: 140 VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAE 199 Query: 182 LSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNA 241 + ++HD+ YGVPSLEELGF T+GL AVW GGETEAL RL++HLERKAWVAN+ERPRMNA Sbjct: 200 IQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNA 259 Query: 242 NSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAAT 301 NSLLASPTGLSPYLRFGCLSCRLFY++L DLYKKVK+NS+PPLSL+GQLLWREFFYTAAT Sbjct: 260 NSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAAT 319 Query: 302 NNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAV 361 NNPRFD+MEGNPIC+QIPWD+NPEALAKWAEG+TGFPWIDAIMTQLRQEGWIHHLARHAV Sbjct: 320 NNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAV 379 Query: 362 ACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRR 421 ACFLTRGDLW+SWE G++VF+ELLLDAD+S+NAGSWMWLSCS+FFQQFFHCYCPVGFGRR Sbjct: 380 ACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRR 439 Query: 422 TDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNI 481 TDP+GDYIRRYLP L+GFP++YIY+PWNAPE +QK AKC+IGV+YP+P+VNHAE SRLNI Sbjct: 440 TDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNI 499 Query: 482 ERMKQIYQQLSRYRGLGLLASVPS 505 ERMKQIYQQLSRYRGL LLASVPS Sbjct: 500 ERMKQIYQQLSRYRGLCLLASVPS 523 >3FY4-A nrPDB Length = 537 Score = 617 bits (1592), Expect = e-177, Method: Composition-based stats. Identities = 250/499 (50%), Positives = 341/499 (68%), Gaps = 17/499 (3%) Query: 2 GVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFA---------GSSNVGINRW 52 G ++ WFRKGLR+HDNPAL+ +G++ + V+++DP + GSS G+NR Sbjct: 4 GSGSLIWFRKGLRVHDNPALEYASKGSEFMYPVFVIDPHYMESDPSAFSPGSSRAGVNRI 63 Query: 53 RFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAA 112 RFLL+ L+DLD++L+KL SRL V +G+P +V R +EW + +L EYD++P+ + D Sbjct: 64 RFLLESLKDLDSSLKKLGSRLLVFKGEPGEVLVRCLQEWKVKRLCFEYDTDPYYQALDVK 123 Query: 113 IKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITS 172 +K A+ GVEV +SHTL++ IIE NGG+PPL+Y+ F + EP ++ + S Sbjct: 124 VKDYASSTGVEVFSPVSHTLFNPAHIIEKNGGKPPLSYQSFLKVAG--EPSCAKSELVMS 181 Query: 173 DVIGKCMTPLSDDHDEKYG-VPSLEELGFDTDGLSS-AVWPGGETEALTRLERHLERKAW 230 + P+ D + VPSLEELG+ D + + GGE+EAL RL + + KAW Sbjct: 182 ---YSSLPPIGDIGNLGISEVPSLEELGYKDDEQADWTPFRGGESEALKRLTKSISDKAW 238 Query: 231 VANFERPRMNANSLLAS-PTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQ 289 VANFE+P+ + ++ L T +SPYL+FGCLS R FY L ++YK VKK++SPP+SL GQ Sbjct: 239 VANFEKPKGDPSAFLKPATTVMSPYLKFGCLSSRYFYQCLQNIYKDVKKHTSPPVSLLGQ 298 Query: 290 LLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQ 349 LLWREFFYT A P FDKM+GN IC QIPW+++ LA W +G+TG+PWIDAIM QL + Sbjct: 299 LLWREFFYTTAFGTPNFDKMKGNRICKQIPWNEDHAMLAAWRDGKTGYPWIDAIMVQLLK 358 Query: 350 EGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQF 409 GW+HHLARH VACFLTRGDL+I WE+G VFE LL+D+DW+IN G+WMWLSCSSFF QF Sbjct: 359 WGWMHHLARHCVACFLTRGDLFIHWEQGRDVFERLLIDSDWAINNGNWMWLSCSSFFYQF 418 Query: 410 FHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKP 469 Y P+ FG++ DP+G YIR +LPVL+ P +YIY+PW AP +Q A C++G +YPKP Sbjct: 419 NRIYSPISFGKKYDPDGKYIRHFLPVLKDMPKQYIYEPWTAPLSVQTKANCIVGKDYPKP 478 Query: 470 MVNHAEASRLNIERMKQIY 488 MV H AS+ +M + Y Sbjct: 479 MVLHDSASKECKRKMGEAY 497 >4JZY-A nrPDB Length = 536 Score = 569 bits (1467), Expect = e-163, Method: Composition-based stats. Identities = 208/508 (40%), Positives = 290/508 (57%), Gaps = 19/508 (3%) Query: 2 GVNAVHWFRKGLRLHDNPALKECIQGAD---TIRCVYILDPWFAGSSNVGINRWRFLLQC 58 G N + WFR GLRLHDNPAL + D + V+I D AG+ NVG NR RFLL Sbjct: 6 GANVI-WFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDS 64 Query: 59 LEDLDANLRKLN---SRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKK 115 L+D+D L+ RL V G+PA +F RL ++ + ++ IE D EP ERD +I+ Sbjct: 65 LQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRS 124 Query: 116 LATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKM-EPLEMPADTITSDV 174 L E ++ + ++SHTL+D +IE NGG PPLTY+ F V + P AD D Sbjct: 125 LCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDA 184 Query: 175 IGKCMTPL-SDDHDEKYGVPSLEELGFDTDGLS---SAVWPGGETEALTRLERHL--ERK 228 + P +P+ E D + W GGET+AL L+ L E+ Sbjct: 185 TFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQH 244 Query: 229 AWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVK--KNSSPPLSL 286 A+ F P ++ SP +S +LRFGCLS R FY+ + DL+K V+ + + Sbjct: 245 AFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLGVQMTGGAHI 304 Query: 287 YGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDK-NPEALAKWAEGRTGFPWIDAIMT 345 GQL+WRE+FYT + NNP +D+MEGN IC+ IPW K N L W G+TGFP ID M Sbjct: 305 TGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFPLIDGAMR 364 Query: 346 QLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSF 405 QL EGW+HH R+ VA FLTRG LW SWE G++ F + LLDADWS+ AG+WMW+S S+F Sbjct: 365 QLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVSSSAF 424 Query: 406 FQQFFH--CYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIG 463 + CPV +R DP+G YI++Y+P L P +++++PW Q+ +CLIG Sbjct: 425 ERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQEQYECLIG 484 Query: 464 VNYPKPMVNHAEASRLNIERMKQIYQQL 491 V+YP+ +++ + A + N+ MK + L Sbjct: 485 VHYPERIIDLSMAVKRNMLAMKSLRNSL 512 >1NP7-A nrPDB Length = 489 Score = 554 bits (1428), Expect = e-158, Method: Composition-based stats. Identities = 134/494 (27%), Positives = 219/494 (44%), Gaps = 24/494 (4%) Query: 5 AVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINR---WR--FLLQCL 59 + WFR LRLHD+ L ++ I VY DP ++ G + WR FL Q + Sbjct: 8 VLVWFRNDLRLHDHEPLHRALKSGLAITAVYCYDPRQFAQTHQGFAKTGPWRSNFLQQSV 67 Query: 60 EDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAA--IKKLA 117 ++L +L+K+ ++L V G P V P++ K+ N + Y E +E D + K Sbjct: 68 QNLAESLQKVGNKLLVTTGLPEQVIPQIAKQINAKTIY--YHREVTQEELDVERNLVKQL 125 Query: 118 TEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGK 177 T G+E TL + + + P + +F+ + K + P Sbjct: 126 TILGIEAKGYWGSTLCHPEDL-PFSIQDLPDLFTKFRKDIEKKKISIRPCFF-----APS 179 Query: 178 CMTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERP 237 + P + E P + D S + GGET L RL+ + + +++ Sbjct: 180 QLLPSPNIKLELTAPPPEFFPQINFDHRSVLAFQGGETAGLARLQDYFWHGDRLKDYKET 239 Query: 238 RMNANSLLAS--PTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREF 295 R N ++ + + SP+L GCLS R Y ++ ++ N S ++ +LLWR+F Sbjct: 240 R---NGMVGADYSSKFSPWLALGCLSPRFIYQEVKRYEQERVSNDSTHWLIF-ELLWRDF 295 Query: 296 FYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHH 355 F A G + PW ++ W G+TG+P +DA M +L G++ + Sbjct: 296 FRFVAQKYGNKLFNRGGLLNKNFPWQEDQVRFELWRSGQTGYPLVDANMRELNLTGFMSN 355 Query: 356 LARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCP 415 R VA FL + +L I W G + FE L+D D N G+W + + + F + Sbjct: 356 RGRQNVASFLCK-NLGIDWRWGAEWFESCLIDYDVCSNWGNWNYTAGIGNDARDFRYFNI 414 Query: 416 VGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAE 475 ++ DP G Y+R +LP L+ P I+ PW QK +GV+YP+P VN + Sbjct: 415 PKQSQQYDPQGTYLRHWLPELKNLPGDKIHQPWLLSATEQKQWGVQLGVDYPRPCVNFHQ 474 Query: 476 A--SRLNIERMKQI 487 + +R IE+M I Sbjct: 475 SVEARRKIEQMGVI 488 >4U63-A nrPDB Length = 498 Score = 537 bits (1382), Expect = e-153, Method: Composition-based stats. Identities = 137/488 (28%), Positives = 213/488 (43%), Gaps = 21/488 (4%) Query: 3 VNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDL 62 + WFRK LRL DN AL ++ + VYI + + G W +L L L Sbjct: 25 APVIVWFRKDLRLSDNLALLAAVEHGGPVIPVYIREK--SAGPLGGAQEW-WLHHSLAAL 81 Query: 63 DANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGV 122 ++L K RL + G + L E + +P G D A+K+ + G+ Sbjct: 82 SSSLEKAGGRLVLASGDAERILRDLISETGADTVVWNRRYDPTGMATDKALKQKLRDDGL 141 Query: 123 EVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTPL 182 V L++ ++ +GG P Y F + + PAD S K P Sbjct: 142 TVRSFSGQLLHEPSRLQTKSGG-PYRVYTPFWRALEGSDEPHAPADPPKSLTAPKVW-PK 199 Query: 183 SDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLE--RKAWVANFERPRMN 240 S+ +P+ + D S +W GET AL +L+ ++ K + + P Sbjct: 200 SEKLSNWKLLPTKPDWAKDF----SDIWTPGETGALDKLDDFIDGALKGYEEGRDFPAKP 255 Query: 241 ANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA 300 A SL LSP+L G +S + L + + N +++WREF Y Sbjct: 256 ATSL------LSPHLAAGEISPAAVWHATKGLSRHIASNDIS--RFRKEIVWREFCYHLL 307 Query: 301 TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA 360 + P + N W + ++ W G TG+P +DA M QL Q G +H+ R Sbjct: 308 FHFPELGEKNWNDSFDAFSWRDDEKSFKAWTRGMTGYPIVDAGMRQLWQHGTMHNRVRMI 367 Query: 361 VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSS-FFQQFFHCYCPVGFG 419 VA FL + L I W +G K F + L+DAD + NA +W W++ S FF + P+ G Sbjct: 368 VASFLIK-HLLIDWRKGEKWFRDTLVDADPASNAANWQWVAGSGADASPFFRIFNPILQG 426 Query: 420 RRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRL 479 + D +GDY+RR++P L KYI+ P+ AP+ K A +G YP P+V+H +A Sbjct: 427 EKFDGDGDYVRRFVPELEKLERKYIHKPFEAPKDALKKAGVELGKTYPLPIVDHGKARER 486 Query: 480 NIERMKQI 487 + + Sbjct: 487 ALAAYAAV 494 >1OWP-A nrPDB Length = 484 Score = 521 bits (1342), Expect = e-148, Method: Composition-based stats. Identities = 137/494 (27%), Positives = 230/494 (46%), Gaps = 26/494 (5%) Query: 1 MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE 60 M + W R+ LRL DN L + + ++ LDP S+++ R +L CL+ Sbjct: 1 MAAPILFWHRRDLRLSDNIGLAAARAQSAQLIGLFCLDPQILQSADMAPARVAYLQGCLQ 60 Query: 61 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA 120 +L ++ SRL +++G P + P+L ++ + D EP+G++RD + A Sbjct: 61 ELQQRYQQAGSRLLLLQGDPQHLIPQLAQQLQAEAVYWNQDIEPYGRDRDGQVAAALKTA 120 Query: 121 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQ-TLVSKMEPLEMPADTITSDVIGKCM 179 G+ + L+ D+I+ G P Y F ++ +P + T D+ + + Sbjct: 121 GIRAVQLWDQLLHSPDQILS-GSGNPYSVYGPFWKNWQAQPKPTPVATPTELVDLSPEQL 179 Query: 180 TPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRM 239 T ++ + +P+L++LGFD DG V P GET A+ RL+ +R +A+++ P+ Sbjct: 180 TAIAPLLLSE--LPTLKQLGFDWDG-GFPVEP-GETAAIARLQEFCDRA--IADYD-PQR 232 Query: 240 NANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPP--LSLYGQLLWREFFY 297 N + A +GLSP L+FG + R + + + + + + +L WREF+ Sbjct: 233 NFPA-EAGTSGLSPALKFGAIGIRQAWQAASAAHALSRSDEARNSIRVWQQELAWREFYQ 291 Query: 298 TAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLA 357 A + P + Q PW+ W + +TG+P +DA M QL + GW+H+ Sbjct: 292 HALYHFPSLADGPYRSLWQQFPWENREALFTAWTQAQTGYPIVDAAMRQLTETGWMHNRC 351 Query: 358 RHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVG 417 R VA FLT+ DL I W G + F + L+D D + N G W W + S + + P Sbjct: 352 RMIVASFLTK-DLIIDWRRGEQFFMQHLVDGDLAANNGGWQWSASSGMDPKPLRIFNPAS 410 Query: 418 FGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEAS 477 ++ D YI+R+LP LR K + I + YP P+VNH Sbjct: 411 QAKKFDATATYIKRWLPELRHVHPKDL---------ISGEITPIERRGYPAPIVNH---- 457 Query: 478 RLNIERMKQIYQQL 491 L ++ K +Y QL Sbjct: 458 NLRQKQFKALYNQL 471 >1U3C-A nrPDB Length = 509 Score = 498 bits (1281), Expect = e-141, Method: Composition-based stats. Identities = 133/496 (26%), Positives = 218/496 (43%), Gaps = 29/496 (5%) Query: 6 VHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDAN 65 + WFR+ LR+ DNPAL ++ + +++ P G + G +L L LD++ Sbjct: 15 IVWFRRDLRVEDNPALAAAVRAGP-VIALFVWAPEEEGHYHPGRVSRWWLKNSLAQLDSS 73 Query: 66 LRKLNSRLFVIRGQPADV-FPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEV 124 LR L + L R + + K +++ + +P RD K + T G+ V Sbjct: 74 LRSLGTCLITKRSTDSVASLLDVVKSTGASQIFFNHLYDPLSLVRDHRAKDVLTAQGIAV 133 Query: 125 IVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKM-----EPLEMPADTITSDVIGKCM 179 + LY+ ++ + G+P + F M PL P I+ DV Sbjct: 134 RSFNADLLYEPWEVTD-ELGRPFSMFAAFWERCLSMPYDPESPLLPPKKIISGDVSKCVA 192 Query: 180 TPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRM 239 PL + D + G +L + S W G+ T + L + + R Sbjct: 193 DPLVFEDDSEKGSNALLARAW------SPGWSNGDKALTTFINGPL------LEYSKNRR 240 Query: 240 NANSLLASPTGLSPYLRFGCLSCRLFYF----KLTDLYKKVKKNSSPPLSLYGQLL-WRE 294 A+S A+ + LSP+L FG +S R + K + + ++L+ + + RE Sbjct: 241 KADS--ATTSFLSPHLHFGEVSVRKVFHLVRIKQVAWANEGNEAGEESVNLFLKSIGLRE 298 Query: 295 FFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIH 354 + + N+P + PW + W +GRTG+P +DA M +L GW+H Sbjct: 299 YSRYISFNHPYSHERPLLGHLKFFPWAVDENYFKAWRQGRTGYPLVDAGMRELWATGWLH 358 Query: 355 HLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCS-SFFQQFFHCY 413 R V+ L + W GMK F + LLDAD +A W +++ + ++F Sbjct: 359 DRIRVVVSS-FFVKVLQLPWRWGMKYFWDTLLDADLESDALGWQYITGTLPDSREFDRID 417 Query: 414 CPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNH 473 P G + DPNG+Y+RR+LP L P +I+ PWNAPE + + A +G NYP P+V Sbjct: 418 NPQFEGYKFDPNGEYVRRWLPELSRLPTDWIHHPWNAPESVLQAAGIELGSNYPLPIVGL 477 Query: 474 AEASRLNIERMKQIYQ 489 EA E + Q++Q Sbjct: 478 DEAKARLHEALSQMWQ 493 >1DNP-A nrPDB Length = 471 Score = 492 bits (1266), Expect = e-139, Method: Composition-based stats. Identities = 120/492 (24%), Positives = 202/492 (41%), Gaps = 34/492 (6%) Query: 6 VHWFRKGLRLHDNPALKEC-IQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDA 64 + WFR+ LRLHDN AL + + +YI P + N+ + + L L Sbjct: 4 LVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWATHNMSPRQAELINAQLNGLQI 63 Query: 65 NLRKLNSRLFVIRGQP----ADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA 120 L + L ++ ++ E ++T L Y E + RD +++ Sbjct: 64 ALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFYNYQYEVNERARDVEVERALRNV 123 Query: 121 GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMT 180 E D +I G ++ ++ P + + + +C+ Sbjct: 124 VCEGFD---------DSVILPPGAVMTGNHEMYKVFT----PFKNAWLKRLREGMPECVA 170 Query: 181 -PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRM 239 P PS+ L + +A +P E A+ +L + + A +E+ R Sbjct: 171 APKVRSSGSIEPSPSIT-LNYPRQSFDTAHFPVEEKAAIAQLRQFCQNGA--GEYEQQR- 226 Query: 240 NANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTA 299 + + LS L G LS R +L + + + L +L+WREF+ Sbjct: 227 -DFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWL-NELIWREFYRHL 284 Query: 300 ATNNPRFDKM-EGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLAR 358 T +P K ++ W NP L W EG+TG+P +DA M QL GW+H+ R Sbjct: 285 ITYHPSLCKHRPFIAWTDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQLNSTGWMHNRLR 344 Query: 359 HAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSS-FFQQFFHCYCPVG 417 A FL + DL I W EG + F L+D D + N G W W + + +F + P Sbjct: 345 MITASFLVK-DLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTDAAPYFRIFNPTT 403 Query: 418 FGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEAS 477 G + D G++IR++LP LR P K +++PW + K + ++YP+P+V H EA Sbjct: 404 QGEKFDHEGEFIRQWLPELRDVPGKVVHEPWKWAQ------KAGVTLDYPQPIVEHKEAR 457 Query: 478 RLNIERMKQIYQ 489 + + + Sbjct: 458 VQTLAAYEAARK 469 >2E0I-A nrPDB Length = 440 Score = 484 bits (1246), Expect = e-137, Method: Composition-based stats. Identities = 127/486 (26%), Positives = 192/486 (39%), Gaps = 59/486 (12%) Query: 3 VNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFA-GSSNVGINRWRFLLQCLED 61 ++ + FR+ LRL DN L + D + V+I DP + F++ L + Sbjct: 1 MDCIFIFRRDLRLEDNTGLNYALSECDRVIPVFIADPRQLINNPYKSEFAVSFMINSLLE 60 Query: 62 LDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAG 121 LD LRK SRL V G+ V R F + + + D PF RD I+K+ E G Sbjct: 61 LDDELRKKGSRLNVFFGEAEKVVSRFFN--KVDAIYVNEDYTPFSISRDEKIRKVCEENG 118 Query: 122 VEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTP 181 +E + L N + F VSK++ E + DV M Sbjct: 119 IEFKAYEDYLLTPKSLFHHRN-------FTSFYNEVSKVKVREPETMEGSFDVTDSSMNV 171 Query: 182 LSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNA 241 + + S ++ GG E L L R+++ + + P N Sbjct: 172 ---------------DFLLTFKKIESPLFRGGRREGLYLLHRNVDFRRR----DYPAENN 212 Query: 242 NSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAAT 301 N LSP+L+FG +S R Y+ + V+ +L WR+FF A Sbjct: 213 N------YRLSPHLKFGTISMREAYYTQKGKEEFVR-----------ELYWRDFFTLLAY 255 Query: 302 NNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAV 361 NP I W+ N W EGRTG+P IDA M L G+I+ R V Sbjct: 256 YNPHVFGHCYRREYDNISWENNESYFEAWKEGRTGYPIIDAGMRMLNSTGYINGRVRMLV 315 Query: 362 ACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRR 421 A FL + L++ W G + F L+D D +IN G+W W++ + F + P + Sbjct: 316 AFFLVKV-LFVDWRWGERYFATKLVDYDPAINNGNWQWIASTGVD-YMFRVFNPWKQQEK 373 Query: 422 TDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNI 481 DP +I+ ++ L+ P P I + K + YP P+VN E Sbjct: 374 FDPEAKFIKEWVEELKDVP----------PSIIHSIYKTKVP-GYPSPIVNWLERVNYVK 422 Query: 482 ERMKQI 487 K + Sbjct: 423 SEYKNV 428 >2VTB-B nrPDB Length = 525 Score = 483 bits (1242), Expect = e-136, Method: Composition-based stats. Identities = 127/456 (27%), Positives = 209/456 (45%), Gaps = 29/456 (6%) Query: 5 AVHWFRKGLRLHDNPALKECIQGADTIRCVYILDP------WFAGSSNVGINRWRFLLQC 58 + WFR LR+ DN AL + +DTI VY LDP F G R FL++C Sbjct: 43 TILWFRNDLRVLDNDALYKAWSSSDTILPVYCLDPRLFHTTHFFNFPKTGALRGGFLMEC 102 Query: 59 LEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSI--EYDSEPFGKER--DAAIK 114 L DL NL K L + G+P ++ P L K++ + E SE ER + +K Sbjct: 103 LVDLRKNLMKRGLNLLIRSGKPEEILPSLAKDFGARTVFAHKETCSEEVDVERLVNQGLK 162 Query: 115 KLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDV 174 ++ +E+I T+Y D + + P Y +F+ V E +S Sbjct: 163 RVGNSTKLELI--WGSTMYHKDDL-PFDVFDLPDVYTQFRKSV------EAKCSIRSSTR 213 Query: 175 IGKCMTPLSDDHDEKYGVPSLEELGFDTDGLSSAV-WPGGETEALTRLERHLERKAWVAN 233 I + P + D+ VP+LE+LG + ++ + + GGE+ + R+ + +K + Sbjct: 214 IPLSLGP-TPSVDDWGDVPTLEKLGVEPQEVTRGMRFVGGESAGVGRVFEYFWKKDLLKV 272 Query: 234 FERPRMNANSLLAS--PTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLL 291 ++ R N +L T SP+L FGC+S R Y ++ K+ N+S L+ +L+ Sbjct: 273 YKETR---NGMLGPDYSTKFSPWLAFGCISPRFIYEEVQRYEKERVANNSTYWVLF-ELI 328 Query: 292 WREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEG 351 WR++F + G P V W ++ + W + +TG+P IDA M +L G Sbjct: 329 WRDYFRFLSIKCGNSLFHLGGPRNVNGKWSQDQKLFESWRDAKTGYPLIDANMKELSTTG 388 Query: 352 WIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFH 411 ++ + R V FL R D+ + W G + FE LLD D N G+W + + + ++ Sbjct: 389 FMSNRGRQIVCSFLVR-DMGLDWRMGAEWFETCLLDYDPCSNYGNWTYGAGVNDPRE-DR 446 Query: 412 CYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDP 447 + + DP G+Y+ +L LR P + + P Sbjct: 447 YFSIPKQAQNYDPEGEYVAFWLQQLRRLPKEKRHWP 482 >2J08-A nrPDB Length = 420 Score = 373 bits (958), Expect = e-103, Method: Composition-based stats. Identities = 103/433 (23%), Positives = 163/433 (37%), Gaps = 46/433 (10%) Query: 4 NAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLD 63 + W R LRLHD+PAL E + + V +LDP + R + L+ + L Sbjct: 3 PLLVWHRGDLRLHDHPALLEALARGPVVGLV-VLDP---NNLKTTPRRRAWFLENVRALR 58 Query: 64 ANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVE 123 R L+V+ G P + P + + P+G+ RD +++ Sbjct: 59 EAYRARGGALWVLEGLPWEKVPEAARRLKAKAVYALTSHTPYGRYRDGRVREAL------ 112 Query: 124 VIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTPLS 183 + L ++ + + Y F L P P + + Sbjct: 113 ---PVPLHLLPAPHLLPPDLPRAYRVYTPFSRLYRGAAPPLPPPEALP------------ 157 Query: 184 DDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANS 243 + G E+ G GE AL L LE K ER R++ Sbjct: 158 --KGPEEGEIPREDPGLPLPE-------PGEEAALAGLRAFLEAKLPRYAEERDRLDGEG 208 Query: 244 LLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNN 303 + LSPY G LS RL ++ ++ +LLWR+F Y + Sbjct: 209 ----GSRLSPYFALGVLSPRL------AAWEAERRGGEGARKWVAELLWRDFSYHLLYHF 258 Query: 304 PRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVAC 363 P + +P PW ++ W EG+TG P +DA M +L G++ + AR A Sbjct: 259 PWMAERPLDPRFQAFPWQEDEALFQAWYEGKTGVPLVDAAMRELHATGFLSNRARMNAAQ 318 Query: 364 FLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSS-FFQQFFHCYCPVGFGRRT 422 F + L + W+ + F LLLD D ++N W W +F + PV G R Sbjct: 319 FAVK-HLLLPWKRCEEAFRHLLLDGDRAVNLQGWQWAGGLGVDAAPYFRVFNPVLQGERH 377 Query: 423 DPNGDYIRRYLPV 435 DP G +++R+ P Sbjct: 378 DPEGRWLKRWAPE 390 >5O8D-A nrPDB Length = 484 Score = 121 bits (303), Expect = 1e-27, Method: Composition-based stats. Identities = 72/373 (19%), Positives = 130/373 (34%), Gaps = 30/373 (8%) Query: 4 NAVHWFRKGLRLHDNPALKE----CIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCL 59 V+W + R DN AL + + V+ L F GI ++ F+L+ L Sbjct: 40 PVVYWMSRDQRAEDNWALLFSRAIAKEANVPVVVVFCLTDEFL---EAGIRQYEFMLKGL 96 Query: 60 EDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATE 119 ++L+ +L + F +RG P + R K++N L D P + ++ I+K+ + Sbjct: 97 QELEVSLSRKKIPSFFLRGDPGEKISRFVKDYNAGTLV--TDFSPL-RIKNQWIEKVISG 153 Query: 120 AGVEVIVRISHTLYDLDKIIEL-----NGGQPPLTYKRFQTLVSKMEPLEMPADTITSDV 174 + +H + + + + +P L + L E S Sbjct: 154 ISIPFFEVDAHNVVPCWEASQKHEYAAHTFRPKLYALLPEFLEEFPELEPNSVTPELSAG 213 Query: 175 IGKCMTPLSDDHDEKYGVPSLEELGFDTDGLSSA-VWPGGETEALTRLERHLERKAWVAN 233 G T + L + D L + GE A +E + + Sbjct: 214 AGMVETLSDVLETGVKALLPERALLKNKDPLFEPWHFEPGEKAAKKVMESFIADRLDSYG 273 Query: 234 FERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWR 293 + + + LSPYL FG +S + + ++ K S L L+W+ Sbjct: 274 ----ALRNDPTKNMLSNLSPYLHFGQISSQRV---VLEVEKAESNPGSKKAFLDEILIWK 326 Query: 294 EFFYTAATNNPRFDKMEGNPICVQIPWDKNPE-------ALAKWAEGRTGFPWIDAIMTQ 346 E NP +D E P + + + L ++ G+T P +A + Sbjct: 327 EISDNFCYYNPGYDGFESFPSWAKESLNAHRNDVRSHIFTLEEFEAGKTHDPLWNASQME 386 Query: 347 LRQEGWIHHLARH 359 L G +H R Sbjct: 387 LLSTGKMHGYTRM 399 >3UMV-A nrPDB Length = 506 Score = 71.3 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 85/458 (18%), Positives = 145/458 (31%), Gaps = 47/458 (10%) Query: 5 AVHWFRKGLRLHDN----PALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE 60 V+W + RL DN A A + + L P + + FLL+ L Sbjct: 40 VVYWMLRDQRLADNWALLHAAGLAAASASPLAVAFALFPRPF-LLSARRRQLGFLLRGLR 98 Query: 61 DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYD-SEPFGKERDAAIKKLATE 119 L A+ + F+ G PA++ P L + + L ++ P + DA + L E Sbjct: 99 RLAADAAARHLPFFLFTGGPAEI-PALVQRLGASTLVADFSPLRPVREALDAVVGDLRRE 157 Query: 120 A-GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSK-MEPLEMPADTITSDVIGK 177 A GV V +H + + + + K F+ VSK M+ + + + V Sbjct: 158 APGVAVHQVDAHNVVPVW----TASAKMEYSAKTFRGKVSKVMDEYLVEFPELPAVVPWD 213 Query: 178 CMTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERP 237 P D D E L + L ++ + ++E Sbjct: 214 REQPEGVDWDALIARVCSEAENVPEIDWCEPGEEAAIEALLGSKDGFLTKR--IKSYETD 271 Query: 238 RMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTD---LYKKVKKNSSPPLSLYGQLLWRE 294 R N + + +GLSPYL FG +S + + L K L + +L Sbjct: 272 R-NDPTKPRALSGLSPYLHFGHISAQRCALEAKKCRHLSPKSVDAFLEELVVRRELA-DN 329 Query: 295 FFYTAATNNPRFDKMEGNPICVQIPWDKNPEAL---AKWAEGRTGFPWIDAIMTQLRQEG 351 F Y + E + E + + +T P +A ++ G Sbjct: 330 FCYYQPQYDSLSGAWEWARKTLMDHAADKREHIYTREQLENAKTHDPLWNASQLEMVHHG 389 Query: 352 WIHHLARHAVACFLTRGDLWISWEEGMKVFEELL--------LDADWSINAGSWMWLSCS 403 +H R A + + W G + +D MW C Sbjct: 390 KMHGFMRMYWAKKI------LEWTSGPEEALSTAIYLNDKYEIDGRDPSGYVGCMWSICG 443 Query: 404 SFF-----QQFF---HCYCPVGFGRRTDPNG--DYIRR 431 + F G R+ D + Y++R Sbjct: 444 LHDQGWKERPVFGKIRYMNYAGCKRKFDVDAYISYVKR 481 >3ZXS-A nrPDB Length = 522 Score = 62.1 bits (149), Expect = 6e-10, Method: Composition-based stats. Identities = 66/395 (16%), Positives = 117/395 (29%), Gaps = 38/395 (9%) Query: 17 DNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVI 76 D PAL+ AD + +++ + + +L + L++ R+ Sbjct: 29 DLPALRAADPAADLVVMAEVMEEGTYVPHH--PQKIALILAAMRKFARRLQERGFRVAYS 86 Query: 77 RGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVI-VRISHTLYDL 135 R D P + E + D + + + V + L Sbjct: 87 RLDDPDTGPSIGAELLRRAAETGAREAVATRPGDWRLIEALEAMPLPVRFLPDDRFLCPA 146 Query: 136 DKIIELNGGQPPLTYKRFQTLV--------SKMEPLEMPADTITSDVIGKCMT-----PL 182 D+ G+ L + F + EP + T + PL Sbjct: 147 DEFARWTEGRKQLRMEWFYREMRRRTGLLMEGDEPAGGKWNFDTENRKPAAPDLLRPRPL 206 Query: 183 SDDHD-EKYGVPSLEELGFD--TDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRM 239 + D E V L E F L W EAL L+ + E+ M Sbjct: 207 RFEPDAEVRAVLDLVEARFPRHFGRLRPFHWATDRAEALRALDHFIRESLPRFGDEQDAM 266 Query: 240 NANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLL-WREFFYT 298 A+ S LS + G L + +++ + + Q+L WRE+ Sbjct: 267 LADDPFLSHALLSSSMNLGLLGPMEVCRRAETEWREGRAPLNAVEGFIRQILGWREYVRG 326 Query: 299 A-ATNNPRFDKMEGNPICVQIP---WDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIH 354 + P + + G +P W K T + A + Q R + H Sbjct: 327 IWTLSGPDYIRSNGLGHSAALPPLYWGK-----------PTRMACLSAAVAQTRDLAYAH 375 Query: 355 HLAR-HAVACFLTRGDLWISWEEGMKVFEELLLDA 388 H+ R F + E + + + +DA Sbjct: 376 HIQRLMVTGNFALLA--GVDPAEVHEWYLSVYIDA 408 >5GAM-A nrPDB Length = 735 Score = 37.1 bits (84), Expect = 0.025, Method: Composition-based stats. Identities = 30/208 (14%), Positives = 62/208 (29%), Gaps = 35/208 (16%) Query: 125 IVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTPLSD 184 + T + + + +PPL+Y++ + ++P+ +P D+ + + + Sbjct: 226 REKRDRTHFKRMRFPPFDDDEPPLSYEQHIENIEPLDPINLPLDSQDDEYVKDWLYDSRP 285 Query: 185 DHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFER-------- 236 ++ V + D E L RL L + N+ Sbjct: 286 LEEDSKKVNGTSYKKWSFDLP--------EMSNLYRLSTPLRDEVTDKNYYYLFDKKSFF 337 Query: 237 PRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFF 296 N+ + P L R + + +S ++ + E+ Sbjct: 338 NGKALNNAIPGGPKFEP------LYPRE-------EEEDYNEFNSIDRVIFRVPIRSEY- 383 Query: 297 YTAATNNPRFDKMEGNPICVQIPWDKNP 324 P P V+IPW NP Sbjct: 384 ---KVAFPHL--YNSRPRSVRIPWYNNP 406 >5M99-B nrPDB Length = 505 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 35/124 (28%), Gaps = 21/124 (16%) Query: 301 TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA 360 + G W N + W G G+ M L + R Sbjct: 121 YYIMSLEDHSGQDHWH---WKINSKGQKVWYFGLFGY-----NMPDLNHD---SQKVREE 169 Query: 361 VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR 420 V + D WIS +G+ F D + + W W ++F + + Sbjct: 170 VKKIV---DFWIS--KGVDGFR-----IDAAKHIYGWSWDDGIQESAEYFEWFRDYVLSK 219 Query: 421 RTDP 424 + D Sbjct: 220 KPDA 223 >2X0P-A nrPDB Length = 618 Score = 34.0 bits (76), Expect = 0.21, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 41/119 (34%), Gaps = 8/119 (6%) Query: 213 GETEALTR--LERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLT 270 GE + L + + + + ++ ++ GLSPY G + + L Sbjct: 275 GEEQYLAQQSIRTFFNISRPGKRYVKTSLSILNM-GFMRGLSPYYMAGTPAINEYIHDLI 333 Query: 271 DLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAK 329 ++ N L + +R ++Y AA + + + W +NP L Sbjct: 334 SADPWLRANGFRILREVASMGFRNYYYEAAIDT----DTPYKKMFSAL-WRENPLTLIA 387 >2B81-A nrPDB Length = 323 Score = 32.8 bits (73), Expect = 0.39, Method: Composition-based stats. Identities = 27/212 (12%), Positives = 58/212 (27%), Gaps = 11/212 (5%) Query: 91 WNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTY 150 + Y E+ + + A + G + L D D G + Sbjct: 27 LGVHIPIENYQFHAPTMEKQVELVQKAEQYGFTGVWLRDVLLQDPDFGDPATGQIYDMMI 86 Query: 151 KRFQTLVSKMEPLEMPADTITSDVIGKCMTPLSDDHDEKYGVPSLE-----ELGFDTDGL 205 + + T+ S + D+ + + + D L Sbjct: 87 YLTYLASKTEKIAFGTSATVLSLRHPLRVAKEIATLDQLFPERIMLGVSSGDRRADFKAL 146 Query: 206 SSAVWPGGET--EALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCR 263 + GE EA LE L + ++ +L+ P+ P G Sbjct: 147 GVSHETRGEKFREAFAYLEEILYKNFPSIQSTLGEVHGANLVPKPSKRVPTFITGFSQQN 206 Query: 264 LFYFKLTD----LYKKVKKNSSPPLSLYGQLL 291 + +F Y + + + + + +L+ Sbjct: 207 MEWFAEHGDGWMYYPRSPVHQAGAIGQWRELV 238 >6D97-A nrPDB Length = 547 Score = 32.8 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 41/111 (36%), Gaps = 21/111 (18%) Query: 386 LDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIY 445 + W+ +A +W W+ +F + G I+ ++ L P ++ Sbjct: 49 VQGSWTASA-NWNWIVDPLNGDKFIKVA---------EVQGTEIKSFMESLSKCPKHGLH 98 Query: 446 DPWNAPE------GIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQ 490 +P APE I A ++G +P V ++L + YQQ Sbjct: 99 NPLKAPERYLMYGDISAKAAHMLG----QPTV-LDFFAKLIQRVSPKSYQQ 144 >6ES9-A nrPDB Length = 551 Score = 32.1 bits (71), Expect = 0.83, Method: Composition-based stats. Identities = 31/169 (18%), Positives = 54/169 (31%), Gaps = 9/169 (5%) Query: 180 TPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRM 239 P + D + +E G D D + GGE E L + K + F+ R+ Sbjct: 335 DPETTDWRGLSMFLAEKEPGTDDDPFPTPGMTGGEIEVLG----YRGMKEYELGFDGFRI 390 Query: 240 NANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTA 299 +LL P F L ++ + V S + R+ F + Sbjct: 391 KGENLLGG----EPGRGFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKS 446 Query: 300 ATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLR 348 PR + V+I + + W + ++A M +L Sbjct: 447 LIEFPRVADK-LAMMAVEIMIARQLTYFSAWEKDHGRRCDLEAGMAKLL 494 >3LGB-A nrPDB Length = 194 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 1/49 (2%) Query: 454 IQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRY-RGLGLLA 501 Q V I NYP + N E + N QQLS + +G+GL A Sbjct: 6 AQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSA 54 >3QR1-A nrPDB Length = 813 Score = 30.1 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 18/38 (47%) Query: 360 AVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSW 397 V L +GD ++ WEEG F E+LL D W Sbjct: 17 NVPEQLIKGDKFLKWEEGSSSFTEILLRVDPKGYFLYW 54 >4CRV-B nrPDB Length = 273 Score = 29.7 bits (65), Expect = 4.0, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 22/52 (42%), Gaps = 3/52 (5%) Query: 13 LRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDA 64 LRL DNP +E ++ + D FA R+L Q +++L Sbjct: 225 LRLSDNPRAREALRQC---LPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 273 >5IDU-A nrPDB Length = 410 Score = 29.7 bits (65), Expect = 4.2, Method: Composition-based stats. Identities = 31/163 (19%), Positives = 49/163 (30%), Gaps = 17/163 (10%) Query: 56 LQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKK 115 L D ++ L S + G L + ++ SEP D A Sbjct: 101 HDGLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALSEP-DAGSDVAAMS 159 Query: 116 LATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVI 175 ++ + D DK NGG Y F + A + +D Sbjct: 160 ------LQARAEGDCYVIDGDKTWISNGGIA-DFYVVFARTGEAPGARGISAFIVDADTP 212 Query: 176 GKCMT---------PLSDDHDEKYGVPSLEELGFDTDGLSSAV 209 G + PL+ H + VP + LG +G A+ Sbjct: 213 GLQIAERIDVIAPHPLARLHFDSARVPRSQMLGAPGEGFKIAM 255 >5GSM-A nrPDB Length = 786 Score = 29.4 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 26/195 (13%), Positives = 54/195 (27%), Gaps = 19/195 (9%) Query: 135 LDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTPLSDDHDEKYGVPS 194 + + + PP+TY T + + + + P+ + Sbjct: 125 PNGPLPRDIYYPPITY-LHPTYLEAVGEWYNAVFPVIRKYLYTNGGPIISVSIDDEPSYW 183 Query: 195 LEELG-FDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSP 253 F TD PGG E LE++ + ++ + + + + P Sbjct: 184 ETIFQPFLTDYNEIITKPGGLWE--KWLEQNYTLEDLRRRYKGDFKDYSEIKVPTSFSEP 241 Query: 254 --------YLRFGCLS--CRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNN 303 + + ++ R Y ++ + P L Q+ WR FF +N Sbjct: 242 LPKLIDWHHFKLWMINEYVRWIYERMAREFDVPISILDPYL---LQVAWRHFFTYMREHN 298 Query: 304 PRFDKMEGNPICVQI 318 Sbjct: 299 --LKIHVWTEFWYSF 311 >1FZ4-C nrPDB Length = 389 Score = 29.4 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 27/74 (36%), Gaps = 8/74 (10%) Query: 260 LSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIP 319 L+ + ++ D + + +L+GQ + REFF A PRF P + Sbjct: 229 LAVEGLWQEVFDWNESAFSVHAVYDALFGQFVRREFFQRLA---PRFGD-NLTPFFIN-- 282 Query: 320 WDKNPEALAKWAEG 333 + +G Sbjct: 283 --QAQTYFQIAKQG 294 >1KB0-A nrPDB Length = 677 Score = 29.4 bits (64), Expect = 4.7, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 15/53 (28%), Gaps = 1/53 (1%) Query: 377 GMKV-FEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDY 428 G + + D W W S + F R DP+G + Sbjct: 183 GAEYGVRGYITAYDAETGERKWRWFSVPGDPSKPFEDESMKRAARTWDPSGKW 235 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.126 0.349 Lambda K H 0.267 0.0390 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,741,695 Number of Sequences: 36641 Number of extensions: 998954 Number of successful extensions: 2428 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 2257 Number of HSP's gapped (non-prelim): 59 length of query: 606 length of database: 10,336,785 effective HSP length: 103 effective length of query: 503 effective length of database: 6,562,762 effective search space: 3301069286 effective search space used: 3301069286 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)