BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P95189 (260 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5YHT-A nrPDB 505 e-144 4N81-A nrPDB 116 1e-26 5EQA-A nrPDB 108 3e-24 2P3V-A nrPDB 103 7e-23 2PCR-A nrPDB 101 3e-22 4AS5-A nrPDB 89 1e-18 2BJI-A nrPDB 86 2e-17 5ZHH-A nrPDB 84 6e-17 3LV0-A nrPDB 83 1e-16 5J16-A nrPDB 82 3e-16 2CZH-A nrPDB 81 4e-16 1IMD-A nrPDB 78 4e-15 2Q74-A nrPDB 77 7e-15 4O7I-A nrPDB 74 5e-14 6IB8-A nrPDB 73 1e-13 3QMF-A nrPDB 70 8e-13 1G0H-A nrPDB 70 1e-12 1VDW-A nrPDB 64 9e-11 3B8B-A nrPDB 62 2e-10 1JP4-A nrPDB 59 2e-09 1KA0-A nrPDB 57 9e-09 1XI6-A nrPDB 55 2e-08 1LBZ-A nrPDB 54 5e-08 2WEF-A nrPDB 51 4e-07 5ESY-A nrPDB 50 1e-06 5DJK-A nrPDB 42 4e-04 1INP-A nrPDB 32 0.29 2OF7-A nrPDB 30 0.78 4WZ6-A nrPDB 30 0.79 2PZF-A nrPDB 29 1.6 1LML-A nrPDB 29 1.9 4M77-E nrPDB 28 3.2 2FE1-A nrPDB 28 5.1 >5YHT-A nrPDB Length = 267 Score = 505 bits (1301), Expect = e-144, Method: Compositional matrix adjust. Identities = 259/260 (99%), Positives = 260/260 (100%) Query: 1 MSHDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRP 60 +SHDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRP Sbjct: 8 VSHDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRP 67 Query: 61 GDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL 120 GDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL Sbjct: 68 GDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL 127 Query: 121 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT 180 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT Sbjct: 128 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT 187 Query: 181 VWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG 240 VWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG Sbjct: 188 VWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG 247 Query: 241 SAVATNGLLHDEVLTRLNAG 260 SAVATNGLLHDEVLTRLNAG Sbjct: 248 SAVATNGLLHDEVLTRLNAG 267 >4N81-A nrPDB Length = 259 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 82/223 (36%), Positives = 115/223 (51%), Gaps = 7/223 (3%) Query: 4 DDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDG 63 DD+ LA LAD A ++ R F A L ID K D +PVT ADR E +R L ++RP DG Sbjct: 8 DDIRLAHRLADVAADIIRPFFRA-PLTIDLKADHSPVTKADRGAEQAMRAILEQERPEDG 66 Query: 64 VLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRR 123 + GEE G S R W++DPIDGT+ F+ G + +LIAL+EDG P +G+++ P Q R Sbjct: 67 IFGEEMGVSRPDARRLWVLDPIDGTRAFIGGRASFGTLIALVEDGRPVLGIINQPIHQER 126 Query: 124 WWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWR 183 W + S +G H S L A L+ +S + + G F + Sbjct: 127 WVGVKDLP--TSFNGEVIH---TRSCPALDHALLATTSPWLFEKEG-EVHFDKIRLKCRD 180 Query: 184 VRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGG 226 GD +Y L++ G D+ E + +D AAL +V AGG Sbjct: 181 TLLGGDCYNYGLLSLGHCDLVVEQGLKFYDFAALVPIVEGAGG 223 >5EQA-A nrPDB Length = 277 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 76/227 (33%), Positives = 119/227 (52%), Gaps = 16/227 (7%) Query: 13 ADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFG-- 70 A+ A ++ R F + I K DL+PVT AD++ E + + + P V GEE G Sbjct: 25 ANAAGDVIRKYFRKNNFDIIHKNDLSPVTIADQSAEEAMVSVILDNFPSHAVYGEEKGWR 84 Query: 71 GSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGR 130 W++DPIDGTK+F+ G P++ +LIALL++G P +G++ P L+ RW G+ Sbjct: 85 CKQDSADYVWVLDPIDGTKSFITGKPLFGTLIALLQNGTPILGIIDQPVLKERWIGITGK 144 Query: 131 GAFASVDGARPHRLSVSSVAELHSASLSFSS---LSGWARPGLRERFIGLTDTVWRVRAY 187 +++G +S + A+L A L +S SG A E FI + D V ++ Y Sbjct: 145 R--TTLNG---QEVSTRTCADLSQAYLYTTSPHLFSGDA----EEAFIRVRDKV-KIPLY 194 Query: 188 G-DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDG 233 G D +Y L++ G VD+ E + +D AL V+ +GG +T G Sbjct: 195 GCDCYAYALLSSGFVDLVVESGLKPYDFLALIPVIEGSGGVITDWKG 241 >2P3V-A nrPDB Length = 256 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 15/251 (5%) Query: 4 DDLMLALALADRADELTRVRFGALDLRIDTKPDLTP-VTDADRAVESDVRQTLGRDRPGD 62 D L ++ L + L + +G +D ++ K VT+ DR + + + + P + Sbjct: 2 DRLDFSIKLLRKVGHLLMIHWGRVD-NVEKKTGFKDIVTEIDREAQRMIVDEIRKFFPDE 60 Query: 63 GVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQR 122 ++ EE G R WI+DPIDGT NFV G+P ++ +A +E+G +GVV APAL Sbjct: 61 NIMAEE--GIFEKGDRLWIIDPIDGTINFVHGLPNFSISLAYVENGEVKLGVVHAPALNE 118 Query: 123 RWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVW 182 +A G GAF +G R +S+ E ++ S+ +G + +R Sbjct: 119 TLYAEEGSGAF--FNGERIRVSENASLEECVGSTGSYVDFTGKFIERMEKR-------TR 169 Query: 183 RVRAYGD-FLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGV-AGPHGG 240 R+R G L+ V G VD +++ WD+AA I+V+EAGG +T G A Sbjct: 170 RIRILGSAALNAAYVGAGRVDFFVTWRINPWDIAAGLIIVKEAGGMVTDFSGKEANAFSK 229 Query: 241 SAVATNGLLHD 251 + + +NGL+HD Sbjct: 230 NFIFSNGLIHD 240 >2PCR-A nrPDB Length = 264 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 73/247 (29%), Positives = 121/247 (48%), Gaps = 21/247 (8%) Query: 18 ELTRVRFGALDLR-IDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFT 76 ++ + FG + I+ K + V+ D+ E +++ + + P V+GEE G + + Sbjct: 20 QVLKENFGKVKKENIEEKGEKDFVSYVDKTSEERIKEVILKFFPDHEVVGEEMGAEGSGS 79 Query: 77 GRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASV 136 +W +DP+DGTKN++ G P++A + L++ P VG V P + +W A+G GA+ V Sbjct: 80 EYRWFIDPLDGTKNYINGFPIFAVSVGLVKGEEPIVGAVYLPYFDKLYWGAKGLGAY--V 137 Query: 137 DGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLT---DTVWRV----RAYGD 189 +G R+ V L A + + G+ R+ I L D + V R Sbjct: 138 NG---KRIKVKDNESLKHAGVVY----GFPSRSRRDISIYLNIFKDVFYEVGSMRRPGAA 190 Query: 190 FLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGS-AVATNGL 248 + C+VAEG D E ++ WD+ A ++++EAGG T V P G S +A N Sbjct: 191 AVDLCMVAEGIFDGMMEFEMKPWDITAGLVILKEAGGVYTL---VGEPFGVSDIIAGNKA 247 Query: 249 LHDEVLT 255 LHD +L Sbjct: 248 LHDFILQ 254 >4AS5-A nrPDB Length = 277 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 72/241 (29%), Positives = 111/241 (46%), Gaps = 22/241 (9%) Query: 9 ALALADRADELTRVRF-GALDLRIDTKP-DLTPVTDADRAVESDVRQTLGRDRPGDGVLG 66 A+ LA +A E+ R +D+ I + P DL VTD + VE + ++ P +G Sbjct: 12 AVILARQAGEMIREALKNEMDVMIKSSPADLVTVTD--QKVEKMLMSSIKEKYPCHSFIG 69 Query: 67 EEF---GGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQR 122 EE G T FT + W++DPIDGT NFV P A I L + G+V + + Sbjct: 70 EESVAAGEKTVFTEQPTWVIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGIVYSCVEDK 129 Query: 123 RWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVW 182 + +G+GAF + +L VS ++ + SL + L +P + + + Sbjct: 130 MYTGRKGKGAFCN-----GQKLQVSQQEDI-TKSLLVTELGSSRKPETLRIVLSNMEKLC 183 Query: 183 RVRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAG 236 + +G ++ CLVA G D E + WD+A I+V EAGG L +D G Sbjct: 184 SIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVL--MDVTGG 241 Query: 237 P 237 P Sbjct: 242 P 242 >2BJI-A nrPDB Length = 277 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 76/243 (31%), Positives = 112/243 (46%), Gaps = 26/243 (10%) Query: 9 ALALADRADELTRVRF-GALDLRIDTKP-DLTPVTDADRAVESDVRQTLGRDRPGDGVLG 66 A+ LA +A E+ R +++ + + P DL VT D+ VE + ++ P +G Sbjct: 12 AVTLAGQAGEVVREALKNEMNIMVKSSPADL--VTATDQKVEKMLITSIKEKYPSHSFIG 69 Query: 67 EEF---GGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQR 122 EE G + T WI+DPIDGT NFV G P A I + + G+V + + Sbjct: 70 EESVAAGEKSILTDNPTWIIDPIDGTTNFVHGFPFVAVSIGFVVNKKMEFGIVYSCLEDK 129 Query: 123 RWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLR-------ERFI 175 + +G+GAF + +L VS ++ + SL + L P ER + Sbjct: 130 MYTGRKGKGAFCN-----GQKLQVSHQEDI-TKSLLVTELGSSRTPETVRIILSNIERLL 183 Query: 176 GLTDTVWRVRAYGD-FLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGV 234 L + +R G L+ CLVA GA D E + WD+A I+V EAGG L LD Sbjct: 184 CL--PIHGIRGVGTAALNMCLVAAGAADAYYEMGIHCWDVAGAGIIVTEAGGVL--LDVT 239 Query: 235 AGP 237 GP Sbjct: 240 GGP 242 >5ZHH-A nrPDB Length = 270 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 78/224 (34%), Positives = 104/224 (46%), Gaps = 20/224 (8%) Query: 40 VTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQ-----WIVDPIDGTKNFVRG 94 VT AD+A E+ V + + R P +L EE G G Q W +DP+DGT N+ Sbjct: 43 VTAADKASEAVVLEIIRRHFPQHSILAEESGK----LGNQDNEYLWAIDPLDGTTNYAHQ 98 Query: 95 VPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHS 154 P + I LL +GVP VGV+ P + A G GA RP + VS +EL S Sbjct: 99 YPAFCVSIGLLINGVPQVGVIYDPFHDELFRGAAGLGA---TRNRRP--IKVSDTSEL-S 152 Query: 155 ASLSFSSLSGWARP---GLRERFIGLTDTVWRVRAYGD-FLSYCLVAEGAVDIAAEPQVS 210 SL + + R F LT VR G L VA G VD E +S Sbjct: 153 KSLLVTGFAYDRRETPDNNYAEFCHLTHLTQGVRRSGSAALDLAHVACGRVDGYWERGIS 212 Query: 211 VWDLAALDIVVREAGGRLTSLDGVA-GPHGGSAVATNGLLHDEV 253 WD+ A I++ EAGG++T+ D G +ATNG +HD + Sbjct: 213 PWDVVAGVILLEEAGGKVTAYDSTPLKIATGRILATNGSIHDNL 256 >3LV0-A nrPDB Length = 267 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 70/214 (32%), Positives = 99/214 (46%), Gaps = 17/214 (7%) Query: 28 DLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTG----RQWIVD 83 +L++ K V+ ADR E + L + RP G L EE S G ++IVD Sbjct: 34 NLQVSLKGPADYVSQADRKAEKIIFNELSKARPKFGFLMEE---SEEIIGEDSQHRFIVD 90 Query: 84 PIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHR 143 P+DGT NF+ G+P +A IAL G GV+ P + A RG GAF + R Sbjct: 91 PLDGTTNFLHGIPFFAVSIALESQGKIVAGVIYNPINDELFTAERGSGAFFN-----DRR 145 Query: 144 LSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDF----LSYCLVAEG 199 VS+ L ++ + + RPG I L + + V F L VA G Sbjct: 146 CRVSARRRLEDCVIA-TGMPHLGRPGHGTYLIELRNVMAEVSGIRRFGTAALDLAYVAAG 204 Query: 200 AVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDG 233 D E + +WD+AA ++VREAGG +T +G Sbjct: 205 RTDGFWEDNLQIWDMAAGILMVREAGGFVTDKEG 238 >5J16-A nrPDB Length = 283 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 74/238 (31%), Positives = 111/238 (46%), Gaps = 24/238 (10%) Query: 28 DLRIDTKPDLTP-VTDADRAVESDVRQTLGRDRPGDGVLGEEFGGST--TFTGRQWIVDP 84 +L I+TK + VT+ D+A E + T+ P VLGEE G T G W+VDP Sbjct: 33 NLTIETKSNPNDLVTNVDKATEDFIFDTILETYPNHQVLGEEGHGHDIDTSKGTVWVVDP 92 Query: 85 IDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRL 144 IDGT NFV +A I + DG P G V + A G GA+ G++P Sbjct: 93 IDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVLYHAKVGEGAYR---GSQP--- 146 Query: 145 SVSSVAELHSASLSFSSL---SGW-ARPGLRERFIGLTDTVWRVRAYGD-FLSYCLVAEG 199 + L+ ++L S + W +P L E F + + RAYG L VA G Sbjct: 147 ----LKPLNDSNLRQSIIGINPNWLTKPILGEIFKEIVNDSRSARAYGSAALEIVSVATG 202 Query: 200 AVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDG----VAGPHGGSAVATNGLLHDEV 253 ++ P++ WD A +++ E G+ ++L G ++GP+ S + N LH E+ Sbjct: 203 NLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPN--SILVGNRGLHQEI 258 >2CZH-A nrPDB Length = 299 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 73/240 (30%), Positives = 105/240 (43%), Gaps = 20/240 (8%) Query: 9 ALALADRADELTRVRFGALDLRIDTKPDLTP-VTDADRAVESDVRQTLGRDRPGDGVLGE 67 A+ LA RA ++ R + R+ TK VT+ D VE + L P + E Sbjct: 34 AVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAE 92 Query: 68 EF---GGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRR 123 E G T WI+DPIDGT NFV P A I GV+ +R Sbjct: 93 EAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERL 152 Query: 124 WWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWR 183 + RGRGAF + RL VS +L S +L + + P + F+ + + Sbjct: 153 YTGRRGRGAFCN-----GQRLRVSGETDL-SKALVLTEIGPKRDPATLKLFLSNMERLLH 206 Query: 184 VRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGP 237 +A+G L+ C +A GA D + + WDLAA +++REAGG + +D GP Sbjct: 207 AKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIV--IDTSGGP 264 >1IMD-A nrPDB Length = 277 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 69/241 (28%), Positives = 108/241 (44%), Gaps = 22/241 (9%) Query: 9 ALALADRADEL-TRVRFGALDLRIDTKP-DLTPVTDADRAVESDVRQTLGRDRPGDGVLG 66 A+ LA +A E+ +++ + + P DL VT D+ VE + ++ P +G Sbjct: 12 AVTLARQAGEVVCEAIKNEMNVMLKSSPVDL--VTATDQKVEKMLISSIKEKYPSHSFIG 69 Query: 67 EEF---GGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQR 122 EE G + T WI+DPIDGT NFV P A I + GVV + + Sbjct: 70 EESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGK 129 Query: 123 RWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVW 182 + A +G+GAF + +L VS ++ + SL + L P + + ++ Sbjct: 130 MYTARKGKGAFCN-----GQKLQVSQQEDI-TKSLLVTELGSSRTPETVRMVLSNMEKLF 183 Query: 183 RVRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAG 236 + +G ++ CLVA G D E + WD+A I+V EAGG L +D G Sbjct: 184 CIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVL--MDVTGG 241 Query: 237 P 237 P Sbjct: 242 P 242 >2Q74-A nrPDB Length = 299 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 82/227 (36%), Positives = 104/227 (45%), Gaps = 8/227 (3%) Query: 39 PVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGR-----QWIVDPIDGTKNFVR 93 PVT D E +R L + RPGD +LGEE GG T W++DPIDGT NFV Sbjct: 55 PVTVVDTDTERLLRDRLAQLRPGDPILGEEGGGPADVTATPSDRVTWVLDPIDGTVNFVY 114 Query: 94 GVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELH 153 G+P +A I G+ G V+ A + + AA G GA + + R H L + V EL Sbjct: 115 GIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLGAHLTDERGR-HVLRCTGVDELS 173 Query: 154 SASLSFS-SLSGWARPGLRERFIGLTDTVWRVRAYGD-FLSYCLVAEGAVDIAAEPQVSV 211 A L S R E + V VR G L C+VA G +D E V V Sbjct: 174 MALLGTGFGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLCMVAAGRLDAYYEHGVQV 233 Query: 212 WDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 258 WD AA ++ EAG R+ AG G VA + DE+L L Sbjct: 234 WDCAAGALIAAEAGARVLLSTPRAGGAGLVVVAAAPGIADELLAALQ 280 >4O7I-A nrPDB Length = 325 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 79/313 (25%), Positives = 129/313 (41%), Gaps = 64/313 (20%) Query: 1 MSHD-DLMLALALADRADELT-RVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRD 58 MS D +L LAL + + ++T V L + K D +PVT D +V++ V + + Sbjct: 1 MSFDKELALALEIVQVSCKITTSVAEHTLTDQTQIKNDKSPVTVGDYSVQAYVNKKIHET 60 Query: 59 RPGDGVLGEE---------------------------------FGGSTTFTGRQWIVDPI 85 P D ++ EE G ST GR W++DPI Sbjct: 61 FPEDQIVAEEDTKTIPEDIFAKVCKHVQIYSDMKDDEIRKSIDLGNSTGGKGRHWVLDPI 120 Query: 86 DGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGA----FASVDGARP 141 DGT F+R +A +A + DG VGV+ P + A +G F+ D Sbjct: 121 DGTLGFLRR-EQYAVCLAFMIDGDIKVGVLGCPNFEGGLIVAAQKGCGAKMFSVNDIKNG 179 Query: 142 HRLSVSSVAELHSASLSFS---SLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAE 198 + VS+ + S S + +R + +T R+ + +++ +A Sbjct: 180 KDIHVSTTPKTSDMCFCESVEVSHTDQSRSKTITERLQVTKPPVRMDSQCKYMA---IAS 236 Query: 199 GAVDI------AAEPQVSVWDLAALDIVVREAGGRLTSLDG----------VAGPHGGSA 242 G D+ Q +WD AA ++V+EAGG++T + G + HG Sbjct: 237 GRADVYLRLPRNLSYQEKIWDHAAGYLIVKEAGGKVTDIYGNDLDFSLGRTLCNNHG--I 294 Query: 243 VATNGLLHDEVLT 255 VA+NG+LH+E + Sbjct: 295 VASNGILHEETVN 307 >6IB8-A nrPDB Length = 271 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 63/204 (30%), Positives = 100/204 (49%), Gaps = 21/204 (10%) Query: 40 VTDADRAVESDVRQTLGRDRPGDGVLGEEFGG-STTFTGRQWIVDPIDGTKNFVRGVPVW 98 VT+ D+A E+ + T+ + P ++ EE G T QW++DP+DGT NF++ +P + Sbjct: 44 VTNVDKAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHF 103 Query: 99 ASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLS 158 A IA+ G V VV P + A RG+G A ++G +RL S+ +L L+ Sbjct: 104 AVSIAVRIKGRTEVAVVYDPMRNELFTATRGQG--AQLNG---YRLRGSTARDLDGTILA 158 Query: 159 FSSLSGWARPGLR--ERFIGLTDTVWRVRAYGDF-------LSYCLVAEGAVDIAAEPQV 209 +G+ + +I + ++ A DF L VA G VD E + Sbjct: 159 ----TGFPFKAKQYATTYINIVGKLFNECA--DFRRTGSAALDLAYVAAGRVDGFFEIGL 212 Query: 210 SVWDLAALDIVVREAGGRLTSLDG 233 WD AA +++VREAGG ++ G Sbjct: 213 RPWDFAAGELLVREAGGIVSDFTG 236 >3QMF-A nrPDB Length = 273 Score = 70.5 bits (171), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 58/227 (25%), Positives = 96/227 (42%), Gaps = 17/227 (7%) Query: 40 VTDADRAVESDVRQTLGRDRPGDGVLGEEFGGS--TTFTGRQWIVDPIDGTKNFVRGVPV 97 VT+ D+ ++ +Q L P +L EE + T WI+DPIDGT N V+ Sbjct: 51 VTNVDKQIQQQFQQFLATYFPEHQLLAEEKSNAMITNEINHLWIMDPIDGTANLVKQQED 110 Query: 98 WASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFAS-VDGARPHRLSVS-SVAELHSA 155 + ++A +G P + V ++ + A RG GAF + + P L + ++ ++ Sbjct: 111 YCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGIKMEEPPSLKLEDAIISFNAQ 170 Query: 156 SLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLA 215 ++ ++ R +G A G L VA+G WD+A Sbjct: 171 VMNLDTVQDLFDASFSYRLVG---------ACG--LDSMRVAKGQFGAHINTNPKPWDIA 219 Query: 216 ALDIVVREAGGRLTSLDGVAGPH--GGSAVATNGLLHDEVLTRLNAG 260 A + ++T+LDG A H G + +N H+ VL LNA Sbjct: 220 AQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKILNAN 266 >1G0H-A nrPDB Length = 252 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 26/179 (14%) Query: 63 GVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQR 122 ++ EE G + ++DPIDG+ NF+ G+P +A + ++ P G+ + Sbjct: 61 NIVSEELGVIDNSSEWTVVIDPIDGSFNFINGIPFFAFCFGVFKNNEPYYGLTYEFLTKS 120 Query: 123 RWWAARGRGAFAS-----VDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGL 177 + A +G+GA+ + V P+ + +S P + L Sbjct: 121 FYEAYKGKGAYLNGRKIKVKDFNPNNIVIS------------------YYPSKKIDLEKL 162 Query: 178 TDTVWRVRAYGDF-LSYCLVAEGAVD--IAAEPQVSVWDLAALDIVVREAGGRLTSLDG 233 + V RVR +G F L C VA+G +D P+V D+A+ I+ +EAG +T +G Sbjct: 163 RNKVKRVRIFGAFGLEMCYVAKGTLDAVFDVRPKVRAVDIASSYIICKEAGALITDENG 221 >1VDW-A nrPDB Length = 254 Score = 63.5 bits (153), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 48/176 (27%), Positives = 84/176 (47%), Gaps = 19/176 (10%) Query: 61 GDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL 120 G V+ EE G + +VDP+DG+ NF+ G+P +A +A+ + P + P + Sbjct: 62 GVNVVSEEIGRIDQGSDYTVVVDPLDGSYNFINGIPFFAVSVAIFHEKDPIYAFIYEPIV 121 Query: 121 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT 180 +R + G+G++ ++G ++ V +AE S+SF + + + D Sbjct: 122 ERLYEGIPGKGSY--LNG---EKIKVRELAE--KPSISFYTKGKGTK---------IIDK 165 Query: 181 VWRVRAYGDF-LSYCLVAEGAVDIAAEPQVSV--WDLAALDIVVREAGGRLTSLDG 233 V R R G L +A GA+D + + + D+AA ++ REAG + LDG Sbjct: 166 VKRTRTLGAIALELAYLARGALDAVVDIRNYLRPTDIAAGVVIAREAGAIVKDLDG 221 >3B8B-A nrPDB Length = 292 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 55/205 (26%), Positives = 92/205 (44%), Gaps = 44/205 (21%) Query: 28 DLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQ-----WIV 82 D I+ K D +P+T ADR + L + P VL EE G + R+ WIV Sbjct: 48 DFEIERKADNSPLTIADRKAHEAIVAILN-ETPF-PVLSEE-GKHMDYAVRRGWDTLWIV 104 Query: 83 DPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFAS------- 135 DP+DGTK F++ + IAL+++ VP +GV+ P + ++A G GA+ Sbjct: 105 DPLDGTKEFIKRNGEFTVNIALVQNAVPVMGVIYVPVKKELYFAVEGTGAYKCSGIVGLE 164 Query: 136 -----------------VDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLT 178 + AR H ++V+S + L + ++ + L+++ G Sbjct: 165 DEGVTLQQMIEKSERMPLADARDHFIAVASRSHLTPETETYIA-------DLKKKH-GNV 216 Query: 179 DTVWRVRAYGDFLSYCLVAEGAVDI 203 + + + G + CLVAEG D+ Sbjct: 217 ELI----SSGSSIKICLVAEGKADV 237 >1JP4-A nrPDB Length = 308 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 70/302 (23%), Positives = 113/302 (37%), Gaps = 68/302 (22%) Query: 2 SHDDLM----LALALADRADELTRVRFGALDLRIDTKPDLTPV-TDADRAVESDVRQTLG 56 SH+ LM A ++A +A + R DL I K T + T ADR V+ + +L Sbjct: 4 SHNVLMRLVASAYSIAQKAGTIVRCVIAEGDLGIVQKTSATDLQTKADRMVQMSICSSLS 63 Query: 57 RDRPGDGVLGEE------------FGGSTTFTGRQ----------------WIVDPIDGT 88 R P ++GEE G + +Q W VDP+DGT Sbjct: 64 RKFPKLTIIGEEDLPPGEVDQELIEDGQSEEILKQPCPSQYSAIKEEDLVVW-VDPVDGT 122 Query: 89 KNFVRGVPVWAS-LIALLEDGVPSVGVVSAP----------ALQRRWWAARGRGAFASVD 137 K + G+ + LI + +G G+++ P L R W G GAF Sbjct: 123 KEYTEGLLDNVTVLIGIAYEGKAIAGIINQPYYNYQAGPDAVLGRTIWGVLGLGAFGFQL 182 Query: 138 GARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVA 197 P + + HS L ++ D V RV G+ + + Sbjct: 183 KEAPAGKHIITTTRSHSNKLVTDCIAAMN-----------PDNVLRVGGAGNKIIQLIEG 231 Query: 198 EGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRL 257 + + + A P WD A ++++ GG+LT + G N L +D+ + + Sbjct: 232 KASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHG------------NPLQYDKEVKHM 279 Query: 258 NA 259 N+ Sbjct: 280 NS 281 >1KA0-A nrPDB Length = 357 Score = 57.0 bits (136), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 56/199 (28%), Positives = 85/199 (42%), Gaps = 28/199 (14%) Query: 77 GRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWW----------- 125 GR W +DPIDGTK F+RG +A +AL+ DGV +G + P L + Sbjct: 136 GRFWCLDPIDGTKGFLRG-EQFAVCLALIVDGVVQLGCIGCPNLVLSSYGAQDLKGHESF 194 Query: 126 -----AARGRGAFA--SVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLT 178 A RG GAF S D ++ V + + ++ + + I Sbjct: 195 GYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDM-ITLEGVEKGHSSHDEQTAIKNK 253 Query: 179 DTVWRVRAYGDFLSYCLVAEGAVD------IAAEPQVSVWDLAALDIVVREAGGRLT-SL 231 + + YCL+A G D I Q +WD AA +++V EAGG T ++ Sbjct: 254 LNISKSLHLDSQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVHEAGGIHTDAM 313 Query: 232 DGVAGPHG-GSAVATNGLL 249 + V G G +AT G++ Sbjct: 314 EDVPLDFGNGRTLATKGVI 332 >1XI6-A nrPDB Length = 262 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 49/168 (29%), Positives = 76/168 (45%), Gaps = 18/168 (10%) Query: 61 GDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL 120 G V+ EE G + IVDP+DG+ NF+ G+P +A +A+ + P ++ P Sbjct: 70 GVNVVSEEVGVIDNESEYTVIVDPLDGSYNFIAGIPFFALSLAVFKKDKPIYAIIYEPMT 129 Query: 121 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT 180 +R + G GAF ++G R+ V + S+SF S R + + Sbjct: 130 ERFFEGIPGEGAF--LNG---KRIKVRKTPD-EKPSISFYS---------RGKGHEIVKH 174 Query: 181 VWRVRAYGDF-LSYCLVAEGAVD--IAAEPQVSVWDLAALDIVVREAG 225 V R R G L +A GA+D + V D+AA I+ +EAG Sbjct: 175 VKRTRTLGAIALELAYLAMGALDGVVDVRKYVRPTDIAAGTIIAKEAG 222 >1LBZ-A nrPDB Length = 252 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 65/235 (27%), Positives = 100/235 (42%), Gaps = 40/235 (17%) Query: 36 DLTPVTDADRAVESDVRQTLGRDR-----PGDGVLGEEFGGSTTFTGRQWI-VDPIDGTK 89 D TP ADR E + L ++R GVLGE G ++ +DP+DGT Sbjct: 38 DGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGE---------GDVFVALDPLDGTF 88 Query: 90 NFVRGVPVWA-SLIALLEDGVPS--VGVVSAPALQRRWWAARGRGAFASVDGARPHRLSV 146 N RG+PV++ SL D + G V A ++ A GA+ + R+ V Sbjct: 89 NATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYY-ADSSGAYRN-----GERIEV 142 Query: 147 SSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAE 206 S EL+ ++ + + P R R G T A G F + +DI Sbjct: 143 SDAEELYCNAIIYYPDRKF--PFKRMRIFGSAATELCFFADGSFDCF-------LDIRPG 193 Query: 207 PQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG-------SAVATNGLLHDEVL 254 + ++D AA + +AGG++T LDG + + + VA N LH ++L Sbjct: 194 KMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLL 248 >2WEF-A nrPDB Length = 311 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 62/264 (23%), Positives = 96/264 (36%), Gaps = 50/264 (18%) Query: 9 ALALADRADELTRVRFGALDLRIDTKPDLTPV-TDADRAVESDVRQTLGRDRPGDGVLGE 67 A ++A +A + R DL I K T + T ADR + + +L R P ++GE Sbjct: 11 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 70 Query: 68 EFGGSTT-----FTGRQWI----------------------VDPIDGTKNFVRGVPVWAS 100 E S QW VDP+DGTK + G+ + Sbjct: 71 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 130 Query: 101 -LIALLEDGVPSVGVVSAP----------ALQRRWWAARGRGAFASVDGARPHRLSVSSV 149 LI + +G GV++ P L R W G GAF P + + Sbjct: 131 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITT 190 Query: 150 AELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQV 209 HS L ++ D V RV G+ + + + + + A P Sbjct: 191 TRSHSNKLVTDCVAAMN-----------PDAVLRVGGAGNKIIQLIEGKASAYVFASPGC 239 Query: 210 SVWDLAALDIVVREAGGRLTSLDG 233 WD A ++++ GG+LT + G Sbjct: 240 KKWDTCAPEVILHAVGGKLTDIHG 263 >5ESY-A nrPDB Length = 346 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 35/109 (32%), Positives = 51/109 (46%), Gaps = 22/109 (20%) Query: 76 TGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRR------------ 123 GR W++DPIDGTK F+RG +A + LLE+G +GV++ P L Sbjct: 127 NGRHWVLDPIDGTKGFLRG-DQYAVALGLLEEGKVVLGVLACPNLPLASIAGNNKNKSSS 185 Query: 124 ------WWAARGRGAFASV--DGARPHRLSVSSVAELHSASLSFSSLSG 164 ++A G G + + + P ++ VSSV AS F S G Sbjct: 186 DEIGCLFFATIGSGTYMQLLDSKSSPVKVQVSSVENPEEASF-FESFEG 233 >5DJK-A nrPDB Length = 288 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 27/64 (42%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 44 DRAVESDVRQTLGRDRPGDGVLGEEFGG--STTFTGRQWIVDPIDGTKNF-VRGVPVWAS 100 DR S + + L +RPGD VL EE + + R WI+DP+DGT+ F G WA Sbjct: 71 DRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRDDWAV 130 Query: 101 LIAL 104 IAL Sbjct: 131 HIAL 134 >1INP-A nrPDB Length = 400 Score = 32.0 bits (71), Expect = 0.29, Method: Compositional matrix adjust. Identities = 44/184 (23%), Positives = 68/184 (36%), Gaps = 34/184 (18%) Query: 82 VDPIDGTKNFVRG----------VPVWASLIALL------EDGVPSVGVVSAPALQRRWW 125 VDPID T +++G P + +L + GVP +GV++ P + + Sbjct: 152 VDPIDSTYQYIKGSADITPNQGIFPSGLQCVTVLIGVYDIQTGVPLMGVINQPFVSQDLH 211 Query: 126 AARGRGAFA---SVDGARPHRL----SVSSVAELHSASLSFSSLSGWARPGL------RE 172 R +G S G H L S S +E S S G R + +E Sbjct: 212 TRRWKGQCYWGLSYLGTNIHSLLPPVSTRSNSEAQSQGTQNPSSEGSCRFSVVISTSEKE 271 Query: 173 RFIGLTDTVWRVRAY----GDFLSYCLVAEGA-VDIAAEPQVSVWDLAALDIVVREAGGR 227 G V R + + S C++ A + I +E WD A ++R GG Sbjct: 272 TIKGALSHVCGERIFRAAGAGYKSLCVILGLADIYIFSEDTTFKWDSCAAHAILRAMGGG 331 Query: 228 LTSL 231 + L Sbjct: 332 MVDL 335 >2OF7-A nrPDB Length = 260 Score = 30.4 bits (67), Expect = 0.78, Method: Compositional matrix adjust. Identities = 21/58 (36%), Positives = 24/58 (41%) Query: 153 HSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVS 210 H A+ S S +G RPGLRER T R YG A IA +VS Sbjct: 24 HMAARSAPSPAGAPRPGLRERKKTRTREAIRAATYGLIRQQGYEATTVEQIAERAEVS 81 >4WZ6-A nrPDB Length = 290 Score = 30.4 bits (67), Expect = 0.79, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Query: 153 HSASLSFSSLSGWARPG-LRERFIGLTDTVWRVRA 186 HS +SF S + W PG ++E IG++ +R R+ Sbjct: 97 HSGRISFCSQNSWIMPGTIKENIIGVSYDEYRYRS 131 >2PZF-A nrPDB Length = 228 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 153 HSASLSFSSLSGWARPG-LRERFIGLTDTVWRVRA 186 HS +SF S W PG ++E IG++ +R R+ Sbjct: 67 HSGRISFCSQFSWIMPGTIKENIIGVSYDEYRYRS 101 >1LML-A nrPDB Length = 478 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 16/27 (59%) Query: 93 RGVPVWASLIALLEDGVPSVGVVSAPA 119 GV WA+ DG P+VGV++ PA Sbjct: 122 EGVLAWATTCQTFSDGHPAVGVINIPA 148 >4M77-E nrPDB Length = 93 Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust. Identities = 14/58 (24%), Positives = 28/58 (48%), Gaps = 2/58 (3%) Query: 35 PDLTPVTDADRAVESDVRQTLGRDRPGDGVL--GEEFGGSTTFTGRQWIVDPIDGTKN 90 P++ P+ D+ + V L +R +G L ++F +W++DP D ++N Sbjct: 4 PEILPLEVIDKTINQKVLIVLQSNREFEGTLVGFDDFVNVILEDAVEWLIDPEDESRN 61 >2FE1-A nrPDB Length = 156 Score = 27.7 bits (60), Expect = 5.1, Method: Compositional matrix adjust. Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 7/94 (7%) Query: 145 SVSSVAELHSASLSFSSLSG--W--ARPGL--RERFIGLTDTVWRVRAYGDFLSYCLVAE 198 +VS ELH+ L+ ++ W AR GL + + + +W SY V + Sbjct: 51 AVSQAQELHTLDLAAYEVANDLWKHARRGLLREDEASNMLEELWEFFKALKVHSYAEVLK 110 Query: 199 GAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLD 232 A +A + V+V+D AA + + GG+L +LD Sbjct: 111 DAFALALKHGVTVYD-AAYVALAEKIGGKLLTLD 143 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5YHT-A nrPDB 332 7e-92 2P3V-A nrPDB 226 5e-60 4AS5-A nrPDB 226 5e-60 2BJI-A nrPDB 225 1e-59 4N81-A nrPDB 224 3e-59 1IMD-A nrPDB 223 8e-59 5ZHH-A nrPDB 218 2e-57 2PCR-A nrPDB 218 2e-57 5EQA-A nrPDB 214 4e-56 2CZH-A nrPDB 212 1e-55 6IB8-A nrPDB 205 2e-53 4O7I-A nrPDB 201 3e-52 5J16-A nrPDB 201 3e-52 3LV0-A nrPDB 199 1e-51 1JP4-A nrPDB 193 5e-50 3QMF-A nrPDB 188 2e-48 2WEF-A nrPDB 186 6e-48 2Q74-A nrPDB 167 3e-42 1VDW-A nrPDB 165 2e-41 1G0H-A nrPDB 162 2e-40 1XI6-A nrPDB 159 8e-40 1LBZ-A nrPDB 158 3e-39 1KA0-A nrPDB 156 7e-39 3B8B-A nrPDB 136 8e-33 5ESY-A nrPDB 119 1e-27 5DJK-A nrPDB 81 4e-16 Sequences not found previously or not previously below threshold: 4QXD-A nrPDB 92 2e-19 1INP-A nrPDB 59 2e-09 1BK4-A nrPDB 32 0.25 2F3D-A nrPDB 32 0.27 3RSJ-A nrPDB 32 0.32 2FHY-A nrPDB 31 0.49 5Q0C-A nrPDB 31 0.80 3K85-A nrPDB 30 1.1 6AYU-A nrPDB 30 1.1 2AN2-A nrPDB 30 1.1 4XQ7-A nrPDB 30 1.2 3E4D-A nrPDB 30 1.3 2QVR-A nrPDB 28 4.2 1WSR-A nrPDB 28 4.2 6DLH-A nrPDB 28 4.4 1LML-A nrPDB 27 6.2 6NIB-A nrPDB 27 6.7 >5YHT-A nrPDB Length = 267 Score = 332 bits (852), Expect = 7e-92, Method: Composition-based stats. Identities = 259/260 (99%), Positives = 260/260 (100%) Query: 1 MSHDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRP 60 +SHDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRP Sbjct: 8 VSHDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRP 67 Query: 61 GDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL 120 GDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL Sbjct: 68 GDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL 127 Query: 121 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT 180 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT Sbjct: 128 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT 187 Query: 181 VWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG 240 VWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG Sbjct: 188 VWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG 247 Query: 241 SAVATNGLLHDEVLTRLNAG 260 SAVATNGLLHDEVLTRLNAG Sbjct: 248 SAVATNGLLHDEVLTRLNAG 267 >2P3V-A nrPDB Length = 256 Score = 226 bits (577), Expect = 5e-60, Method: Composition-based stats. Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 15/251 (5%) Query: 4 DDLMLALALADRADELTRVRFGALDLRIDTKPDLTP-VTDADRAVESDVRQTLGRDRPGD 62 D L ++ L + L + +G +D ++ K VT+ DR + + + + P + Sbjct: 2 DRLDFSIKLLRKVGHLLMIHWGRVD-NVEKKTGFKDIVTEIDREAQRMIVDEIRKFFPDE 60 Query: 63 GVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQR 122 ++ EE G R WI+DPIDGT NFV G+P ++ +A +E+G +GVV APAL Sbjct: 61 NIMAEE--GIFEKGDRLWIIDPIDGTINFVHGLPNFSISLAYVENGEVKLGVVHAPALNE 118 Query: 123 RWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVW 182 +A G GAF +G R +S+ E ++ S+ +G + +R Sbjct: 119 TLYAEEGSGAF--FNGERIRVSENASLEECVGSTGSYVDFTGKFIERMEKR-------TR 169 Query: 183 RVRAYGD-FLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGV-AGPHGG 240 R+R G L+ V G VD +++ WD+AA I+V+EAGG +T G A Sbjct: 170 RIRILGSAALNAAYVGAGRVDFFVTWRINPWDIAAGLIIVKEAGGMVTDFSGKEANAFSK 229 Query: 241 SAVATNGLLHD 251 + + +NGL+HD Sbjct: 230 NFIFSNGLIHD 240 >4AS5-A nrPDB Length = 277 Score = 226 bits (577), Expect = 5e-60, Method: Composition-based stats. Identities = 70/255 (27%), Positives = 112/255 (43%), Gaps = 19/255 (7%) Query: 6 LMLALALADRADELTRVRF-GALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGV 64 + A+ LA +A E+ R +D+ I + P VT D+ VE + ++ P Sbjct: 9 MDYAVILARQAGEMIREALKNEMDVMIKSSP-ADLVTVTDQKVEKMLMSSIKEKYPCHSF 67 Query: 65 LGEEF---GGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL 120 +GEE G T FT + W++DPIDGT NFV P A I L + G+V + Sbjct: 68 IGEESVAAGEKTVFTEQPTWVIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGIVYSCVE 127 Query: 121 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT 180 + + +G+GAF + +L VS ++ + SL + L +P + + Sbjct: 128 DKMYTGRKGKGAFCN-----GQKLQVSQQEDI-TKSLLVTELGSSRKPETLRIVLSNMEK 181 Query: 181 VWRVRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGV 234 + + +G ++ CLVA G D E + WD+A I+V EAGG L + G Sbjct: 182 LCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTGG 241 Query: 235 AGP-HGGSAVATNGL 248 +A N + Sbjct: 242 PFDLMSRRIIAANSI 256 >2BJI-A nrPDB Length = 277 Score = 225 bits (574), Expect = 1e-59, Method: Composition-based stats. Identities = 69/266 (25%), Positives = 114/266 (42%), Gaps = 20/266 (7%) Query: 6 LMLALALADRADELTRVRF-GALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGV 64 + A+ LA +A E+ R +++ + + P VT D+ VE + ++ P Sbjct: 9 MDYAVTLAGQAGEVVREALKNEMNIMVKSSP-ADLVTATDQKVEKMLITSIKEKYPSHSF 67 Query: 65 LGEEF---GGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL 120 +GEE G + T WI+DPIDGT NFV G P A I + + G+V + Sbjct: 68 IGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHGFPFVAVSIGFVVNKKMEFGIVYSCLE 127 Query: 121 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT 180 + + +G+GAF + +L VS ++ + SL + L P + + Sbjct: 128 DKMYTGRKGKGAFCN-----GQKLQVSHQEDI-TKSLLVTELGSSRTPETVRIILSNIER 181 Query: 181 VWRVRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGV 234 + + +G L+ CLVA GA D E + WD+A I+V EAGG L + G Sbjct: 182 LLCLPIHGIRGVGTAALNMCLVAAGAADAYYEMGIHCWDVAGAGIIVTEAGGVLLDVTGG 241 Query: 235 AGPHGGS--AVATNGLLHDEVLTRLN 258 ++N L + + + Sbjct: 242 PFDLMSRRVIASSNKTLAERIAKEIQ 267 >4N81-A nrPDB Length = 259 Score = 224 bits (570), Expect = 3e-59, Method: Composition-based stats. Identities = 83/258 (32%), Positives = 122/258 (47%), Gaps = 10/258 (3%) Query: 4 DDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDG 63 DD+ LA LAD A ++ R F A L ID K D +PVT ADR E +R L ++RP DG Sbjct: 8 DDIRLAHRLADVAADIIRPFFRA-PLTIDLKADHSPVTKADRGAEQAMRAILEQERPEDG 66 Query: 64 VLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRR 123 + GEE G S R W++DPIDGT+ F+ G + +LIAL+EDG P +G+++ P Q R Sbjct: 67 IFGEEMGVSRPDARRLWVLDPIDGTRAFIGGRASFGTLIALVEDGRPVLGIINQPIHQER 126 Query: 124 WWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWR 183 W + + + S L A L+ +S + + G F + Sbjct: 127 WVGVKDLPTSFN-----GEVIHTRSCPALDHALLATTSPWLFEKEG-EVHFDKIRLKCRD 180 Query: 184 VRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPH---GG 240 GD +Y L++ G D+ E + +D AAL +V AGG + G Sbjct: 181 TLLGGDCYNYGLLSLGHCDLVVEQGLKFYDFAALVPIVEGAGGIMRDWQNRPLNKNSVGE 240 Query: 241 SAVATNGLLHDEVLTRLN 258 A + L + L+ + Sbjct: 241 VIAAGDHHLIEPALSAME 258 >1IMD-A nrPDB Length = 277 Score = 223 bits (567), Expect = 8e-59, Method: Composition-based stats. Identities = 68/266 (25%), Positives = 113/266 (42%), Gaps = 20/266 (7%) Query: 6 LMLALALADRADELTRVRF-GALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGV 64 + A+ LA +A E+ +++ + + P + VT D+ VE + ++ P Sbjct: 9 MDYAVTLARQAGEVVCEAIKNEMNVMLKSSP-VDLVTATDQKVEKMLISSIKEKYPSHSF 67 Query: 65 LGEEF---GGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL 120 +GEE G + T WI+DPIDGT NFV P A I + GVV + Sbjct: 68 IGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE 127 Query: 121 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT 180 + + A +G+GAF + +L VS ++ + SL + L P + + Sbjct: 128 GKMYTARKGKGAFCN-----GQKLQVSQQEDI-TKSLLVTELGSSRTPETVRMVLSNMEK 181 Query: 181 VWRVRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGV 234 ++ + +G ++ CLVA G D E + WD+A I+V EAGG L + G Sbjct: 182 LFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGG 241 Query: 235 AGPHGGS--AVATNGLLHDEVLTRLN 258 A N +L + + + Sbjct: 242 PFDLMSRRVIAANNRILAERIAKEIQ 267 >5ZHH-A nrPDB Length = 270 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 79/246 (32%), Positives = 109/246 (44%), Gaps = 13/246 (5%) Query: 19 LTRVRFGALDLRIDTKPDLTP-VTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTT-FT 76 + + G L+ I K VT AD+A E+ V + + R P +L EE G Sbjct: 21 VLQGYLGKLEDAITEKGRPGDLVTAADKASEAVVLEIIRRHFPQHSILAEESGKLGNQDN 80 Query: 77 GRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASV 136 W +DP+DGT N+ P + I LL +GVP VGV+ P + A G GA + Sbjct: 81 EYLWAIDPLDGTTNYAHQYPAFCVSIGLLINGVPQVGVIYDPFHDELFRGAAGLGATRNR 140 Query: 137 DGARPHRLSVSSVAELHSASLSFSSLSGWARP---GLRERFIGLTDTVWRVRAYGD-FLS 192 + VS +EL S SL + + R F LT VR G L Sbjct: 141 -----RPIKVSDTSEL-SKSLLVTGFAYDRRETPDNNYAEFCHLTHLTQGVRRSGSAALD 194 Query: 193 YCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAG-PHGGSAVATNGLLHD 251 VA G VD E +S WD+ A I++ EAGG++T+ D G +ATNG +HD Sbjct: 195 LAHVACGRVDGYWERGISPWDVVAGVILLEEAGGKVTAYDSTPLKIATGRILATNGSIHD 254 Query: 252 EVLTRL 257 + L Sbjct: 255 NLSRAL 260 >2PCR-A nrPDB Length = 264 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 71/256 (27%), Positives = 120/256 (46%), Gaps = 15/256 (5%) Query: 6 LMLALALADRADELTRVRFGALDLR-IDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGV 64 L +A A ++ + FG + I+ K + V+ D+ E +++ + + P V Sbjct: 8 LEVAKIAALAGGQVLKENFGKVKKENIEEKGEKDFVSYVDKTSEERIKEVILKFFPDHEV 67 Query: 65 LGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRW 124 +GEE G + + +W +DP+DGTKN++ G P++A + L++ P VG V P + + Sbjct: 68 VGEEMGAEGSGSEYRWFIDPLDGTKNYINGFPIFAVSVGLVKGEEPIVGAVYLPYFDKLY 127 Query: 125 WAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRV 184 W A+G GA+ + R+ V L A + + +R + D + V Sbjct: 128 WGAKGLGAYVN-----GKRIKVKDNESLKHAGVVY-GFPSRSRRDISIYLNIFKDVFYEV 181 Query: 185 ----RAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG 240 R + C+VAEG D E ++ WD+ A ++++EAGG T V P G Sbjct: 182 GSMRRPGAAAVDLCMVAEGIFDGMMEFEMKPWDITAGLVILKEAGGVYTL---VGEPFGV 238 Query: 241 S-AVATNGLLHDEVLT 255 S +A N LHD +L Sbjct: 239 SDIIAGNKALHDFILQ 254 >5EQA-A nrPDB Length = 277 Score = 214 bits (544), Expect = 4e-56, Method: Composition-based stats. Identities = 76/264 (28%), Positives = 122/264 (46%), Gaps = 18/264 (6%) Query: 7 MLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLG 66 +A A+ A ++ R F + I K DL+PVT AD++ E + + + P V G Sbjct: 19 DVANKAANAAGDVIRKYFRKNNFDIIHKNDLSPVTIADQSAEEAMVSVILDNFPSHAVYG 78 Query: 67 EEFG--GSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRW 124 EE G W++DPIDGTK+F+ G P++ +LIALL++G P +G++ P L+ RW Sbjct: 79 EEKGWRCKQDSADYVWVLDPIDGTKSFITGKPLFGTLIALLQNGTPILGIIDQPVLKERW 138 Query: 125 WAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRV 184 G+ + +S + A+L A L +S E FI + D V Sbjct: 139 IGITGKRTTLN-----GQEVSTRTCADLSQAYLYTTS-PHLFSGDAEEAFIRVRDKVKIP 192 Query: 185 RAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDG---------VA 235 D +Y L++ G VD+ E + +D AL V+ +GG +T G ++ Sbjct: 193 LYGCDCYAYALLSSGFVDLVVESGLKPYDFLALIPVIEGSGGVITDWKGHQLRWEASPLS 252 Query: 236 GPHGGSAV-ATNGLLHDEVLTRLN 258 + V A + +H + L L Sbjct: 253 IATSFNVVAAGDKQIHQQALDSLQ 276 >2CZH-A nrPDB Length = 299 Score = 212 bits (539), Expect = 1e-55, Method: Composition-based stats. Identities = 71/240 (29%), Positives = 102/240 (42%), Gaps = 18/240 (7%) Query: 9 ALALADRADELTRVRFGALDLRIDTKPDLTP-VTDADRAVESDVRQTLGRDRPGDGVLGE 67 A+ LA RA ++ R + R+ TK VT+ D VE + L P + E Sbjct: 34 AVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAE 92 Query: 68 E---FGGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRR 123 E G T WI+DPIDGT NFV P A I GV+ +R Sbjct: 93 EAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERL 152 Query: 124 WWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWR 183 + RGRGAF + RL VS +L S +L + + P + F+ + + Sbjct: 153 YTGRRGRGAFCN-----GQRLRVSGETDL-SKALVLTEIGPKRDPATLKLFLSNMERLLH 206 Query: 184 VRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGP 237 +A+G L+ C +A GA D + + WDLAA +++REAGG + G Sbjct: 207 AKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLD 266 >6IB8-A nrPDB Length = 271 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 74/261 (28%), Positives = 114/261 (43%), Gaps = 11/261 (4%) Query: 3 HDDLMLALALADRADELTRVRFGALD-LRIDTKPDLTPVTDADRAVESDVRQTLGRDRPG 61 H L +A+ A +A L + D + K VT+ D+A E+ + T+ + P Sbjct: 6 HPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQ 65 Query: 62 DGVLGEEFGG-STTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL 120 ++ EE G T QW++DP+DGT NF++ +P +A IA+ G V VV P Sbjct: 66 HTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMR 125 Query: 121 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFI--GLT 178 + A RG+GA + +RL S+ +L L+ + I L Sbjct: 126 NELFTATRGQGAQLN-----GYRLRGSTARDLDGTILATGFPFKAKQYATTYINIVGKLF 180 Query: 179 DTVWRVRAYGD-FLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAG- 236 + R G L VA G VD E + WD AA +++VREAGG ++ G Sbjct: 181 NECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNY 240 Query: 237 PHGGSAVATNGLLHDEVLTRL 257 G+ VA N + +L + Sbjct: 241 MLTGNIVAGNPRVVKAMLANM 261 >4O7I-A nrPDB Length = 325 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 77/314 (24%), Positives = 127/314 (40%), Gaps = 60/314 (19%) Query: 1 MSHD-DLMLALALADRADELT-RVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRD 58 MS D +L LAL + + ++T V L + K D +PVT D +V++ V + + Sbjct: 1 MSFDKELALALEIVQVSCKITTSVAEHTLTDQTQIKNDKSPVTVGDYSVQAYVNKKIHET 60 Query: 59 RPGDGVLGEE---------------------------------FGGSTTFTGRQWIVDPI 85 P D ++ EE G ST GR W++DPI Sbjct: 61 FPEDQIVAEEDTKTIPEDIFAKVCKHVQIYSDMKDDEIRKSIDLGNSTGGKGRHWVLDPI 120 Query: 86 DGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGA----FASVDGARP 141 DGT F+R +A +A + DG VGV+ P + A +G F+ D Sbjct: 121 DGTLGFLRR-EQYAVCLAFMIDGDIKVGVLGCPNFEGGLIVAAQKGCGAKMFSVNDIKNG 179 Query: 142 HRLSVSSVAELHSASLSFS---SLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAE 198 + VS+ + S S + +R + +T R+ + +++ +A Sbjct: 180 KDIHVSTTPKTSDMCFCESVEVSHTDQSRSKTITERLQVTKPPVRMDSQCKYMA---IAS 236 Query: 199 GAVDIAA------EPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG--------SAVA 244 G D+ Q +WD AA ++V+EAGG++T + G VA Sbjct: 237 GRADVYLRLPRNLSYQEKIWDHAAGYLIVKEAGGKVTDIYGNDLDFSLGRTLCNNHGIVA 296 Query: 245 TNGLLHDEVLTRLN 258 +NG+LH+E + + Sbjct: 297 SNGILHEETVNVVK 310 >5J16-A nrPDB Length = 283 Score = 201 bits (510), Expect = 3e-52, Method: Composition-based stats. Identities = 74/256 (28%), Positives = 109/256 (42%), Gaps = 21/256 (8%) Query: 8 LALALADRADELTRVRFGALDLRIDTKPDLTP-VTDADRAVESDVRQTLGRDRPGDGVLG 66 A L A + +L I+TK + VT+ D+A E + T+ P VLG Sbjct: 14 FAQGLIQEAGIRIKQ-LMEQNLTIETKSNPNDLVTNVDKATEDFIFDTILETYPNHQVLG 72 Query: 67 EEFGGSTTFT--GRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRW 124 EE G T G W+VDPIDGT NFV +A I + DG P G V + Sbjct: 73 EEGHGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVLY 132 Query: 125 WAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSG----WARPGLRERFIGLTDT 180 A G GA+ G++P + L+ ++L S + +P L E F + + Sbjct: 133 HAKVGEGAYR---GSQP-------LKPLNDSNLRQSIIGINPNWLTKPILGEIFKEIVND 182 Query: 181 VWRVRAYGD-FLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHG 239 RAYG L VA G ++ P++ WD A +++ E G+ ++L G Sbjct: 183 SRSARAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTIS 242 Query: 240 GS--AVATNGLLHDEV 253 G + N LH E+ Sbjct: 243 GPNSILVGNRGLHQEI 258 >3LV0-A nrPDB Length = 267 Score = 199 bits (505), Expect = 1e-51, Method: Composition-based stats. Identities = 74/258 (28%), Positives = 113/258 (43%), Gaps = 13/258 (5%) Query: 10 LALADRADELTRVRFGAL-DLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEE 68 + A +A +G + +L++ K V+ ADR E + L + RP G L EE Sbjct: 15 VQAAMKAGRSLVRDYGEVQNLQVSLKGPADYVSQADRKAEKIIFNELSKARPKFGFLMEE 74 Query: 69 FGGS-TTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAA 127 + ++IVDP+DGT NF+ G+P +A IAL G GV+ P + A Sbjct: 75 SEEIIGEDSQHRFIVDPLDGTTNFLHGIPFFAVSIALESQGKIVAGVIYNPINDELFTAE 134 Query: 128 RGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT---VWRV 184 RG GAF + R L ++ + + RPG I L + V + Sbjct: 135 RGSGAFFNDRRCRVSA-----RRRLEDCVIA-TGMPHLGRPGHGTYLIELRNVMAEVSGI 188 Query: 185 RAYG-DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPH-GGSA 242 R +G L VA G D E + +WD+AA ++VREAGG +T +G + Sbjct: 189 RRFGTAALDLAYVAAGRTDGFWEDNLQIWDMAAGILMVREAGGFVTDKEGGNDIFRKKNI 248 Query: 243 VATNGLLHDEVLTRLNAG 260 +A N + ++ L G Sbjct: 249 IAGNEHIRIKLERALKKG 266 >1JP4-A nrPDB Length = 308 Score = 193 bits (491), Expect = 5e-50, Method: Composition-based stats. Identities = 67/301 (22%), Positives = 107/301 (35%), Gaps = 66/301 (21%) Query: 2 SHDDLM----LALALADRADELTRVRFGALDLRIDTKPDLTPV-TDADRAVESDVRQTLG 56 SH+ LM A ++A +A + R DL I K T + T ADR V+ + +L Sbjct: 4 SHNVLMRLVASAYSIAQKAGTIVRCVIAEGDLGIVQKTSATDLQTKADRMVQMSICSSLS 63 Query: 57 RDRPGDGVLGEEFGGSTT---------------------------FTGRQWIVDPIDGTK 89 R P ++GEE VDP+DGTK Sbjct: 64 RKFPKLTIIGEEDLPPGEVDQELIEDGQSEEILKQPCPSQYSAIKEEDLVVWVDPVDGTK 123 Query: 90 NFVRGVPVWA-SLIALLEDGVPSVGVVSAP----------ALQRRWWAARGRGAFASVDG 138 + G+ LI + +G G+++ P L R W G GAF Sbjct: 124 EYTEGLLDNVTVLIGIAYEGKAIAGIINQPYYNYQAGPDAVLGRTIWGVLGLGAFGFQLK 183 Query: 139 ARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAE 198 P + + HS L ++ D V RV G+ + + + Sbjct: 184 EAPAGKHIITTTRSHSNKLVTDCIAAM-----------NPDNVLRVGGAGNKIIQLIEGK 232 Query: 199 GAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 258 + + A P WD A ++++ GG+LT + G N L +D+ + +N Sbjct: 233 ASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHG------------NPLQYDKEVKHMN 280 Query: 259 A 259 + Sbjct: 281 S 281 >3QMF-A nrPDB Length = 273 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 60/241 (24%), Positives = 100/241 (41%), Gaps = 18/241 (7%) Query: 27 LDLRIDTKPDLTP-VTDADRAVESDVRQTLGRDRPGDGVLGEEFGG--STTFTGRQWIVD 83 +++ +TK VT+ D+ ++ +Q L P +L EE T WI+D Sbjct: 37 MEMTTETKRHRFDLVTNVDKQIQQQFQQFLATYFPEHQLLAEEKSNAMITNEINHLWIMD 96 Query: 84 PIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFAS-VDGARPH 142 PIDGT N V+ + ++A +G P + V ++ + A RG GAF + + P Sbjct: 97 PIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGIKMEEPP 156 Query: 143 RLSVSS-VAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAV 201 L + + ++ ++ ++ R +G A G L VA+G Sbjct: 157 SLKLEDAIISFNAQVMNLDTVQDLFDASFSYRLVG---------ACG--LDSMRVAKGQF 205 Query: 202 DIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPH--GGSAVATNGLLHDEVLTRLNA 259 WD+AA + ++T+LDG A H G + +N H+ VL LNA Sbjct: 206 GAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKILNA 265 Query: 260 G 260 Sbjct: 266 N 266 >2WEF-A nrPDB Length = 311 Score = 186 bits (473), Expect = 6e-48, Method: Composition-based stats. Identities = 65/293 (22%), Positives = 104/293 (35%), Gaps = 62/293 (21%) Query: 6 LMLALALADRADELTRVRFGALDLRIDTKPDLTPV-TDADRAVESDVRQTLGRDRPGDGV 64 + A ++A +A + R DL I K T + T ADR + + +L R P + Sbjct: 8 VASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTI 67 Query: 65 LGEEFGGSTT-----FTGRQWI----------------------VDPIDGTKNFVRGVPV 97 +GEE S QW VDP+DGTK + G+ Sbjct: 68 IGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLD 127 Query: 98 WA-SLIALLEDGVPSVGVVSAP----------ALQRRWWAARGRGAFASVDGARPHRLSV 146 LI + +G GV++ P L R W G GAF P + Sbjct: 128 NVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHI 187 Query: 147 SSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAE 206 + HS L ++ D V RV G+ + + + + + A Sbjct: 188 ITTTRSHSNKLVTDCVAAM-----------NPDAVLRVGGAGNKIIQLIEGKASAYVFAS 236 Query: 207 PQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLNA 259 P WD A ++++ GG+LT + G N L + + + +N+ Sbjct: 237 PGCKKWDTCAPEVILHAVGGKLTDIHG------------NVLQYHKDVKHMNS 277 >2Q74-A nrPDB Length = 299 Score = 167 bits (423), Expect = 3e-42, Method: Composition-based stats. Identities = 86/242 (35%), Positives = 109/242 (45%), Gaps = 9/242 (3%) Query: 25 GALDLRIDTKPDLT-PVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGR----- 78 G D + K T PVT D E +R L + RPGD +LGEE GG T Sbjct: 40 GDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPILGEEGGGPADVTATPSDRV 99 Query: 79 QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDG 138 W++DPIDGT NFV G+P +A I G+ G V+ A + + AA G GA + + Sbjct: 100 TWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLGAHLTDER 159 Query: 139 ARPHRLSVSSVAELHSASLSFS-SLSGWARPGLRERFIGLTDTVWRVRAYGDF-LSYCLV 196 R H L + V EL A L S R E + V VR G L C+V Sbjct: 160 GR-HVLRCTGVDELSMALLGTGFGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLCMV 218 Query: 197 AEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTR 256 A G +D E V VWD AA ++ EAG R+ AG G VA + DE+L Sbjct: 219 AAGRLDAYYEHGVQVWDCAAGALIAAEAGARVLLSTPRAGGAGLVVVAAAPGIADELLAA 278 Query: 257 LN 258 L Sbjct: 279 LQ 280 >1VDW-A nrPDB Length = 254 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 57/250 (22%), Positives = 101/250 (40%), Gaps = 29/250 (11%) Query: 8 LALALADRADELTRVRFG--ALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVL 65 +A+ + D FG I P D+ E+ + G V+ Sbjct: 9 IAIDIIRDFDHNIMPLFGNPKASETISISPSGDETKVVDKVAENIIISKFKDL--GVNVV 66 Query: 66 GEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWW 125 EE G + +VDP+DG+ NF+ G+P +A +A+ + P + P ++R + Sbjct: 67 SEEIGRIDQGSDYTVVVDPLDGSYNFINGIPFFAVSVAIFHEKDPIYAFIYEPIVERLYE 126 Query: 126 AARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVR 185 G+G++ + ++ V +AE S+SF + + + D V R R Sbjct: 127 GIPGKGSYLN-----GEKIKVRELAE--KPSISFYTKGKGTK---------IIDKVKRTR 170 Query: 186 AYGD-FLSYCLVAEGAVDIAAEPQ--VSVWDLAALDIVVREAGGRLTSLDGV------AG 236 G L +A GA+D + + + D+AA ++ REAG + LDG + Sbjct: 171 TLGAIALELAYLARGALDAVVDIRNYLRPTDIAAGVVIAREAGAIVKDLDGKDVEITFSA 230 Query: 237 PHGGSAVATN 246 + +A N Sbjct: 231 TEKVNIIAAN 240 >1G0H-A nrPDB Length = 252 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 59/258 (22%), Positives = 106/258 (41%), Gaps = 27/258 (10%) Query: 12 LADRADELTRVRFGALDLR--IDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEF 69 +A ++ FG D + T P D+ E + L ++ EE Sbjct: 10 IAKEIEKEILPYFGRKDKSYVVGTSPSGDETEIFDKISEDIALKYLKSL--NVNIVSEEL 67 Query: 70 GGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARG 129 G + ++DPIDG+ NF+ G+P +A + ++ P G+ + + A +G Sbjct: 68 GVIDNSSEWTVVIDPIDGSFNFINGIPFFAFCFGVFKNNEPYYGLTYEFLTKSFYEAYKG 127 Query: 130 RGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGD 189 +GA+ + ++ V + + ++ S P + L + V RVR +G Sbjct: 128 KGAYLN-----GRKIKV---KDFNPNNIVIS-----YYPSKKIDLEKLRNKVKRVRIFGA 174 Query: 190 F-LSYCLVAEGAVDI--AAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGS----- 241 F L C VA+G +D P+V D+A+ I+ +EAG +T +G + Sbjct: 175 FGLEMCYVAKGTLDAVFDVRPKVRAVDIASSYIICKEAGALITDENGDELKFDLNATDRL 234 Query: 242 --AVATNGLLHDEVLTRL 257 VA + + D +L L Sbjct: 235 NIIVANSKEMLDIILDLL 252 >1XI6-A nrPDB Length = 262 Score = 159 bits (403), Expect = 8e-40, Method: Composition-based stats. Identities = 55/234 (23%), Positives = 88/234 (37%), Gaps = 22/234 (9%) Query: 9 ALALADRADELTRVRFGALD--LRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLG 66 A+ + + FG D + P D+ E + + G V+ Sbjct: 18 AIDIISDFETTIMPFFGNPDGGKLVKISPSGDETKLVDKLAEDLILSRITEL--GVNVVS 75 Query: 67 EEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWA 126 EE G + IVDP+DG+ NF+ G+P +A +A+ + P ++ P +R + Sbjct: 76 EEVGVIDNESEYTVIVDPLDGSYNFIAGIPFFALSLAVFKKDKPIYAIIYEPMTERFFEG 135 Query: 127 ARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRA 186 G GAF + R+ V + S+SF S + V R R Sbjct: 136 IPGEGAFLN-----GKRIKVRKTPD-EKPSISFYSRGKGH---------EIVKHVKRTRT 180 Query: 187 YGD-FLSYCLVAEGAVD--IAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGP 237 G L +A GA+D + V D+AA I+ +EAG + G Sbjct: 181 LGAIALELAYLAMGALDGVVDVRKYVRPTDIAAGTIIAKEAGALIKDSAGKDID 234 >1LBZ-A nrPDB Length = 252 Score = 158 bits (399), Expect = 3e-39, Method: Composition-based stats. Identities = 66/265 (24%), Positives = 105/265 (39%), Gaps = 33/265 (12%) Query: 9 ALALADRADELTRVRFGALDLRIDTKP-----DLTPVTDADRAVESDVRQTLGRDRPGDG 63 AL ++ R ++ LR K D TP ADR E + L ++R Sbjct: 6 ALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKER--VT 63 Query: 64 VLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPS---VGVVSAPAL 120 V+ EE G +DP+DGT N RG+PV++ + G V A Sbjct: 64 VVTEESGVLGEG-DVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLAT 122 Query: 121 QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT 180 ++A GA+ + R+ VS EL+ ++ + + P R R G T Sbjct: 123 GDEYYA-DSSGAYRN-----GERIEVSDAEELYCNAIIYYPDRKF--PFKRMRIFGSAAT 174 Query: 181 VWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG 240 A G F + +DI + ++D AA + +AGG++T LDG + + Sbjct: 175 ELCFFADGSFDCF-------LDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKK 227 Query: 241 -------SAVATNGLLHDEVLTRLN 258 + VA N LH ++L + Sbjct: 228 FDMQERLNIVAANEKLHPKLLELIK 252 >1KA0-A nrPDB Length = 357 Score = 156 bits (395), Expect = 7e-39, Method: Composition-based stats. Identities = 74/329 (22%), Positives = 117/329 (35%), Gaps = 86/329 (26%) Query: 5 DLMLALALADRADELTRVRFGAL----DLRIDTKPDLTPVTDADRAVESDVRQTLGRDRP 60 +L++A +A LT+ + D TK D +PVT D A ++ + + + P Sbjct: 6 ELLVATQAVRKASLLTKRIQSEVISHKDSTTITKNDNSPVTTGDYAAQTIIINAIKSNFP 65 Query: 61 GD-----------------GVLGEEFGGSTTF---------------------------- 75 D G+L E + Sbjct: 66 DDKVVGEESSSGLSDAFVSGILNEIKANDEVYNKNYKKDDFLFTNDQFPLKSLEDVRQII 125 Query: 76 ---------TGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL------ 120 GR W +DPIDGTK F+RG +A +AL+ DGV +G + P L Sbjct: 126 DFGNYEGGRKGRFWCLDPIDGTKGFLRG-EQFAVCLALIVDGVVQLGCIGCPNLVLSSYG 184 Query: 121 ----------QRRWWAARGRGAFAS--VDGARPHRLSVSSVAELHSASLSFSSLSGWARP 168 + A RG GAF S D ++ V + + ++ + Sbjct: 185 AQDLKGHESFGYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDM-ITLEGVEKGHSS 243 Query: 169 GLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAA------EPQVSVWDLAALDIVVR 222 + I + + YCL+A G D+ Q +WD AA +++V Sbjct: 244 HDEQTAIKNKLNISKSLHLDSQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVH 303 Query: 223 EAGGRLTS-LDGVAGPHG-GSAVATNGLL 249 EAGG T ++ V G G +AT G++ Sbjct: 304 EAGGIHTDAMEDVPLDFGNGRTLATKGVI 332 >3B8B-A nrPDB Length = 292 Score = 136 bits (343), Expect = 8e-33, Method: Composition-based stats. Identities = 60/241 (24%), Positives = 99/241 (41%), Gaps = 49/241 (20%) Query: 7 MLALALADRADELTRVRFG--ALDLRIDTKPDLTPVTDADRAVESDVRQTLGRD-RPGDG 63 M A+ A +A E + D I+ K D +P+T ADR + L P Sbjct: 25 MAAIDAALKAGEKILSIYEDPKSDFEIERKADNSPLTIADRKAHEAIVAILNETPFP--- 81 Query: 64 VLGEEFGGSTTFT-----GRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAP 118 VL EE G + WIVDP+DGTK F++ + IAL+++ VP +GV+ P Sbjct: 82 VLSEE-GKHMDYAVRRGWDTLWIVDPLDGTKEFIKRNGEFTVNIALVQNAVPVMGVIYVP 140 Query: 119 ALQRRWWAARGRGAFAS------------------------VDGARPHRLSVSSVAELHS 154 + ++A G GA+ + AR H ++V+S + L Sbjct: 141 VKKELYFAVEGTGAYKCSGIVGLEDEGVTLQQMIEKSERMPLADARDHFIAVASRSHLTP 200 Query: 155 ASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSV-WD 213 + ++ + ++ G + + + G + CLVAEG D+ ++ WD Sbjct: 201 ETETYIA--------DLKKKHGNVELI----SSGSSIKICLVAEGKADVYPRFAPTMEWD 248 Query: 214 L 214 Sbjct: 249 T 249 >5ESY-A nrPDB Length = 346 Score = 119 bits (298), Expect = 1e-27, Method: Composition-based stats. Identities = 67/311 (21%), Positives = 100/311 (32%), Gaps = 85/311 (27%) Query: 30 RIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGV--LGEEFGG---------------- 71 + +K D +PVT AD ++ V L ++ + + EE G Sbjct: 32 DVQSKSDKSPVTVADYGSQAVVSLVLEKELSSEPFSLVAEEDSGDLRKDGSQDTLERITK 91 Query: 72 -------------------------------STTFTGRQWIVDPIDGTKNFVRGVPVWAS 100 GR W++DPIDGTK F+RG +A Sbjct: 92 LVNDTLATEESFNGSTLSTDDLLRAIDCGTSEGGPNGRHWVLDPIDGTKGFLRG-DQYAV 150 Query: 101 LIALLEDGVPSVGVVSAPALQR------------------RWWAARGRGAFASV--DGAR 140 + LLE+G +GV++ P L ++A G G + + + Sbjct: 151 ALGLLEEGKVVLGVLACPNLPLASIAGNNKNKSSSDEIGCLFFATIGSGTYMQLLDSKSS 210 Query: 141 PHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVR-AYGDFLSYCLVAEG 199 P ++ VSSV AS F S G I V Y ++ G Sbjct: 211 PVKVQVSSVENPEEASF-FESFEGAHSLHDLSSSIANKLGVKAPPVRIDSQAKYGALSRG 269 Query: 200 AVDIAAE-----PQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG--------SAVATN 246 I + +WD A IVV EAGG +T G + N Sbjct: 270 DGAIYLRFPHKGYREKIWDHVAGAIVVTEAGGIVTDAAGKPLDFSKGKYLDLDTGIIVAN 329 Query: 247 GLLHDEVLTRL 257 L +L + Sbjct: 330 EKLMPLLLKAV 340 >4QXD-A nrPDB Length = 293 Score = 92.1 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 40/237 (16%), Positives = 72/237 (30%), Gaps = 43/237 (18%) Query: 26 ALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQ------ 79 ++ I K D + VT D + + + P ++GEE + + Sbjct: 27 KEEVEIKYKSDGSEVTQVDTQSQQIIFSIIKNKYPTINIIGEEDVENGIPDNQLPTITQL 86 Query: 80 ----------------WIVDPIDGTKNFVR-GVPVWASLIALLEDGVPSVGVVSAPALQR 122 VDP+DGT + L+ + G P +G+VS P Sbjct: 87 SFGSLENKIININDIIIYVDPLDGTDCYTHKQYDSVCVLVGVTYKGKPMIGIVSKPFYNN 146 Query: 123 RWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVW 182 A + +S S+ L+ + S + + I + Sbjct: 147 EITFAI------------ENYISSISLQPLNDKIIFVCS-----KKNDIQHLIKSFPDPY 189 Query: 183 RVR-AYGDFLSYCLVAEGAVDIAAEPQVS--VWDLAALDIVVREAGGRLTSLDGVAG 236 V+ G + DI P + WD A +++ GG + + G Sbjct: 190 EVKYKGGSGAKMMAIIHQEADIYYHPLIQSCTWDTLAAQVILEAQGGIVCDIYGNPL 246 >5DJK-A nrPDB Length = 288 Score = 81.0 bits (198), Expect = 4e-16, Method: Composition-based stats. Identities = 54/204 (26%), Positives = 74/204 (36%), Gaps = 25/204 (12%) Query: 42 DADRAVESDVRQTLGRDRPGDGVLGEEFGG--STTFTGRQWIVDPIDGTKNF-VRGVPVW 98 DR S + + L +RPGD VL EE + + R WI+DP+DGT+ F G W Sbjct: 69 AGDRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRDDW 128 Query: 99 ASLIALL---EDGVPSV--GVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELH 153 A IAL +G P + V+ PA + GA P + + + Sbjct: 129 AVHIALWRRSSNGQPEITDAAVALPARGNVVYRTD-----TVTSGAAPAGVPGTLRIAVS 183 Query: 154 SASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVS-VW 212 + RP I T + V V +G VD W Sbjct: 184 A-----------TRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEW 232 Query: 213 DLAALDIVVREAGGRLTSLDGVAG 236 D AA V+ AG + LDG Sbjct: 233 DSAAPAGVMLAAGMHASRLDGSPL 256 >1INP-A nrPDB Length = 400 Score = 59.0 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 42/247 (17%), Positives = 75/247 (30%), Gaps = 36/247 (14%) Query: 21 RVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRD-RPGDGVLGEEFGGSTTFTGRQ 79 ++ +T L+ V + ++ + + + +D D L Sbjct: 91 KIIMRLGPTEEETVALLSKVLNGNKLASEALAKVVHQDVFFSDPALDSVEINIPQDILGI 150 Query: 80 WIVDPIDGTKNFVRGVPV--------------WASLIALL--EDGVPSVGVVSAPALQRR 123 W+ DPID T +++G LI + + GVP +GV++ P + + Sbjct: 151 WV-DPIDSTYQYIKGSADITPNQGIFPSGLQCVTVLIGVYDIQTGVPLMGVINQPFVSQD 209 Query: 124 WWAARGRGAFASVDGARPHRLS-----VSSVAELHSASLSFSSLSGWAR----------- 167 R +G + VS+ + + S + S Sbjct: 210 LHTRRWKGQCYWGLSYLGTNIHSLLPPVSTRSNSEAQSQGTQNPSSEGSCRFSVVISTSE 269 Query: 168 PGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAA--EPQVSVWDLAALDIVVREAG 225 + + RA G V G DI E WD A ++R G Sbjct: 270 KETIKGALSHVCGERIFRAAGAGYKSLCVILGLADIYIFSEDTTFKWDSCAAHAILRAMG 329 Query: 226 GRLTSLD 232 G + L Sbjct: 330 GGMVDLK 336 >1BK4-A nrPDB Length = 337 Score = 32.1 bits (71), Expect = 0.25, Method: Composition-based stats. Identities = 31/233 (13%), Positives = 62/233 (26%), Gaps = 41/233 (17%) Query: 37 LTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGS-----TTFTGRQWIVDPIDGTKNF 91 V D V L ++ EE + DP+DG+ N Sbjct: 67 GDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSN- 125 Query: 92 VRGVPVWASLIALLEDGVPS----------------VGV-VSAPALQRRWWAARGRGAFA 134 + + ++ + G + A G +F Sbjct: 126 IDCLVSIGTIFGIYRKKSTDEPSTKDALQPGRNLVAAGYALYGSATMLVLAGGSGVNSFM 185 Query: 135 SVDGARPHRLSVSSVAELHSASLSFS---SLSGWARPGLRERFIGLTDTVWRVRAYGDFL 191 +D A + V ++ +S + P + E YG Sbjct: 186 -LDPAIGEFILVDKNVKIKKKGNIYSLNEGYAKDFDPAVTEYIQKKKFPPDNSSPYGARY 244 Query: 192 SYCLVAE-------GAVDIAAEPQVSV-------WDLAALDIVVREAGGRLTS 230 +VA+ G + + + S ++ + ++ +AGG T+ Sbjct: 245 VGSMVADVHRTLVYGGIFLYPANKKSPDGKLRLLYECNPMAFIMEKAGGMATT 297 >2F3D-A nrPDB Length = 338 Score = 32.1 bits (71), Expect = 0.27, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 16/59 (27%), Gaps = 5/59 (8%) Query: 37 LTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGS-----TTFTGRQWIVDPIDGTKN 90 V D V L ++ EE + DP+DG+ N Sbjct: 68 GDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSN 126 >3RSJ-A nrPDB Length = 413 Score = 31.7 bits (70), Expect = 0.32, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 29/93 (31%), Gaps = 2/93 (2%) Query: 27 LDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIVDPI- 85 K DL + DR VE + + +P + S G+ ++D I Sbjct: 296 NTDNFVRKNDLAYINVVDRDVEYRLYADISIAKPEKIIKLIRTSNSNNSLGQIIVMDSIG 355 Query: 86 -DGTKNFVRGVPVWASLIALLEDGVPSVGVVSA 117 + T NF L+ + + + Sbjct: 356 NNCTMNFQNNNGGNIGLLGFHSNNLVASSWYYN 388 >2FHY-A nrPDB Length = 374 Score = 31.3 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 15/59 (25%), Gaps = 5/59 (8%) Query: 37 LTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFG-----GSTTFTGRQWIVDPIDGTKN 90 V D V L ++ EE DP+DG+ N Sbjct: 104 GDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSN 162 >5Q0C-A nrPDB Length = 339 Score = 30.5 bits (67), Expect = 0.80, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 16/59 (27%), Gaps = 5/59 (8%) Query: 37 LTPVTDADRAVESDVRQTLGRDRPGDGVLGEE-----FGGSTTFTGRQWIVDPIDGTKN 90 V D S V L ++ EE DP+DG+ N Sbjct: 68 GDEVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSN 126 >3K85-A nrPDB Length = 357 Score = 30.1 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 35/99 (35%), Gaps = 8/99 (8%) Query: 42 DADRAVESDVRQTLGRDRPGDGVLGE------EFGGSTTFTGRQWIVDPIDGTKNFVRG- 94 D S V GR R ++ E E + + ID ++G Sbjct: 191 IVDELESSMVLYFTGRSRSSAAIINEQKKNTSEGNQTAIEAMHKIKQSAIDTKLALLKGD 250 Query: 95 VPVWASLIAL-LEDGVPSVGVVSAPALQRRWWAARGRGA 132 V +A ++ E+ G ++ P +Q + A G GA Sbjct: 251 VGEFARILGEGWENKKKMAGAITNPMIQEAFDVATGAGA 289 >6AYU-A nrPDB Length = 347 Score = 30.1 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 5/124 (4%) Query: 66 GEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWW 125 GEE G + VDPIDG+ +G+ A + + D + + + Sbjct: 82 GEEVGN-GDGPECDFAVDPIDGSTLMSKGM-TNAISVLAVADRGTMFDPSAVFYMNKI-- 137 Query: 126 AARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVR 185 A G A +D P ++ +VA++ S+ ++ RP + + T R+R Sbjct: 138 -AVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRPRHAQLIHDVRATGARIR 196 Query: 186 AYGD 189 D Sbjct: 197 LITD 200 >2AN2-A nrPDB Length = 360 Score = 30.1 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 21/91 (23%), Gaps = 10/91 (10%) Query: 23 RFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIV 82 L+ + V+ D + + EE G W++ Sbjct: 277 ALVELNKAVLYSYKKQGVSIVDHHTAASQFKRFEEQ--------EEEAGRKLTGDWTWLI 328 Query: 83 DPIDG--TKNFVRGVPVWASLIALLEDGVPS 111 PI G T F R P Sbjct: 329 PPISGSATHIFHRSYDNSIVKPNYFYQDKPY 359 >4XQ7-A nrPDB Length = 359 Score = 29.7 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 19/61 (31%), Gaps = 1/61 (1%) Query: 36 DLTPVTDADRAVE-SDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRG 94 D T D +E + + + E+ R I+DP D T N G Sbjct: 257 DEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKKERPIILDPADPTLNVAEG 316 Query: 95 V 95 Sbjct: 317 Y 317 >3E4D-A nrPDB Length = 278 Score = 29.7 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 27/89 (30%), Gaps = 10/89 (11%) Query: 129 GRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAY- 187 G GA S S+ A + + S + W+ P L + R A Sbjct: 151 GHGAMTIALKNPERFKSCSAFAPIVAP-----SSADWSEPALEKYLGADRAAWRRYDACS 205 Query: 188 ----GDFLSYCLVAEGAVDIAAEPQVSVW 212 G L+ +G D E + W Sbjct: 206 LVEDGARFPEFLIDQGKADSFLEKGLRPW 234 >2QVR-A nrPDB Length = 332 Score = 28.2 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 26/234 (11%), Positives = 59/234 (25%), Gaps = 50/234 (21%) Query: 42 DADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTG-----RQWIVDPIDGTKNFVRGVP 96 D ++ L G+ EE F G ++DP+DG+ N Sbjct: 64 KLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNI----- 118 Query: 97 VWASLIALLE----------------------DGVPSVG-VVSAPALQRRWWAARGRGAF 133 + + + + G VV + + G AF Sbjct: 119 DVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAF 178 Query: 134 A--------SVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVR 185 + R ++ + + T+ + R Sbjct: 179 TYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDKSTNRPYTSR 238 Query: 186 AYGDFLSYCL--VAEGAVDIAAEPQVSV-------WDLAALDIVVREAGGRLTS 230 G ++ + +G + + ++ + + +AGG+ + Sbjct: 239 YIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYECNPMAFLAEQAGGKASD 292 >1WSR-A nrPDB Length = 375 Score = 27.8 bits (60), Expect = 4.2, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 15/40 (37%) Query: 219 IVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 258 + EAGG L L G V +N ++ L + Sbjct: 90 LFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKDLALMQ 129 >6DLH-A nrPDB Length = 734 Score = 27.8 bits (60), Expect = 4.4, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 25/61 (40%) Query: 69 FGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAAR 128 G ++ T + VD + G N G PVW+S I L DG S L ++ Sbjct: 609 DGILSSDTEIKITVDHVAGFTNLGNGAPVWSSPILNLTDGKGSFAYNYTLQLGTDYYDFE 668 Query: 129 G 129 G Sbjct: 669 G 669 >1LML-A nrPDB Length = 478 Score = 27.4 bits (59), Expect = 6.2, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 16/29 (55%) Query: 93 RGVPVWASLIALLEDGVPSVGVVSAPALQ 121 GV WA+ DG P+VGV++ PA Sbjct: 122 EGVLAWATTCQTFSDGHPAVGVINIPAAN 150 >6NIB-A nrPDB Length = 367 Score = 27.4 bits (59), Expect = 6.7, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 14/35 (40%) Query: 43 ADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTG 77 D+ + + + L + P V+G E +G Sbjct: 320 GDKKWDDEAIRVLSKTFPHHEVVGIEGSREIVLSG 354 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.125 0.326 Lambda K H 0.267 0.0387 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,274,328 Number of Sequences: 36641 Number of extensions: 366248 Number of successful extensions: 1130 Number of sequences better than 10.0: 47 Number of HSP's better than 10.0 without gapping: 66 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 950 Number of HSP's gapped (non-prelim): 95 length of query: 260 length of database: 10,336,785 effective HSP length: 95 effective length of query: 165 effective length of database: 6,855,890 effective search space: 1131221850 effective search space used: 1131221850 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 58 (27.0 bits)