BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P93832 (405 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5J32-A nrPDB 747 0.0 3U1H-A nrPDB 424 e-119 1A05-A nrPDB 397 e-111 4IWH-A nrPDB 396 e-110 1V5B-A nrPDB 372 e-103 1CM7-A nrPDB 365 e-101 1CNZ-A nrPDB 362 e-100 1XAD-A nrPDB 358 2e-99 1IDM-A nrPDB 346 1e-95 3VMJ-A nrPDB 343 9e-95 1VLC-A nrPDB 340 7e-94 3VML-A nrPDB 338 3e-93 3VMK-A nrPDB 332 2e-91 3UDO-A nrPDB 315 3e-86 3ASJ-A nrPDB 189 2e-48 2G4O-A nrPDB 188 4e-48 3FMX-X nrPDB 180 1e-45 1WPW-A nrPDB 180 1e-45 4Y1P-A nrPDB 176 1e-44 5HN5-A nrPDB 168 4e-42 2D1C-A nrPDB 167 8e-42 3TY3-A nrPDB 154 5e-38 5YVT-A nrPDB 152 2e-37 3BLV-B nrPDB 138 5e-33 2IV0-A nrPDB 137 1e-32 2E5M-A nrPDB 135 3e-32 5GRH-B nrPDB 116 2e-26 3BLX-A nrPDB 116 2e-26 1XGV-A nrPDB 97 1e-20 1HQS-A nrPDB 96 3e-20 2D4V-A nrPDB 90 1e-18 1AI3-A nrPDB 89 4e-18 5M2E-A nrPDB 83 2e-16 3DMS-A nrPDB 80 2e-15 6C0E-A nrPDB 74 1e-13 4AOY-A nrPDB 42 4e-04 1ZOR-A nrPDB 39 0.004 2UXQ-A nrPDB 31 0.84 6BL1-B nrPDB 31 1.2 4GYR-A nrPDB 30 1.6 1PC2-A nrPDB 29 4.2 4HCX-A nrPDB 28 6.1 2PWJ-A nrPDB 28 6.6 2RI0-A nrPDB 28 7.8 5XJV-A nrPDB 28 8.3 2QFY-A nrPDB 28 8.9 >5J32-A nrPDB Length = 403 Score = 747 bits (1928), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/367 (100%), Positives = 367/367 (100%) Query: 39 GKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEE 98 GKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEE Sbjct: 37 GKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEE 96 Query: 99 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS 158 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS Sbjct: 97 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS 156 Query: 159 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 218 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE Sbjct: 157 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 216 Query: 219 TARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD 278 TARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD Sbjct: 217 TARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD 276 Query: 279 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT 338 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT Sbjct: 277 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT 336 Query: 339 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD 398 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD Sbjct: 337 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD 396 Query: 399 SQVPASV 405 SQVPASV Sbjct: 397 SQVPASV 403 >3U1H-A nrPDB Length = 390 Score = 424 bits (1089), Expect = e-119, Method: Compositional matrix adjust. Identities = 220/366 (60%), Positives = 259/366 (70%), Gaps = 2/366 (0%) Query: 39 GKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEE 98 G + I +LPGDGIGPEV+ A VL+ G EF F IGGAA+D G PLPEE Sbjct: 20 GAMKKKIAVLPGDGIGPEVMEAAIEVLKAVAERFGHEFEFEYGLIGGAAIDEAGTPLPEE 79 Query: 99 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS 158 T+ + SDA+LLGA+GG KWD N LRPEKGLL IR L +FANLRP V L DAS Sbjct: 80 TLDVCRGSDAILLGAVGGPKWDQNPSELRPEKGLLGIRKGLDLFANLRPVKVYDSLADAS 139 Query: 159 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 218 LK+EV EGVDL++VRELTGG+YFGEP + E GEE +T +Y EI+RI R AFE Sbjct: 140 PLKKEVIEGVDLVIVRELTGGLYFGEPS--ERYEEGEEAAVDTLLYTREEIERIIRKAFE 197 Query: 219 TARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD 278 A R+ K+ SVDKANVLE+S LWR+ +A EYPDVEL HM VDNAAMQL+R+P+QFD Sbjct: 198 LALTRKKKVTSVDKANVLESSRLWREVAEEVAKEYPDVELEHMLVDNAAMQLIRNPRQFD 257 Query: 279 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT 338 IVT N+FGDILSDEASMITGS+GMLPSASLS G GL+EP+HGSAPDIAG+ ANPLAT Sbjct: 258 VIVTENMFGDILSDEASMITGSLGMLPSASLSTDGLGLYEPVHGSAPDIAGKGIANPLAT 317 Query: 339 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD 398 ILSAAM+L+Y G E+ AK IE AV L G+RT DI G K V EM +EV +V Sbjct: 318 ILSAAMMLRYSFGLEEEAKAIEKAVEKVLAEGYRTADIAKPGGKYVSTTEMTDEVKAAVV 377 Query: 399 SQVPAS 404 ++ S Sbjct: 378 DELATS 383 >1A05-A nrPDB Length = 358 Score = 397 bits (1021), Expect = e-111, Method: Compositional matrix adjust. Identities = 200/354 (56%), Positives = 255/354 (72%), Gaps = 2/354 (0%) Query: 45 ITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAK 104 I + GDGIGPE+V+ A+ VL + E +GGAALD PLP ++ A Sbjct: 4 IAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDPLPAASLQLAM 63 Query: 105 ESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREV 164 +DAV+LGA+GG +WD RPE+GLL++R L ++ANLRPA + PQL+DAS L+ E+ Sbjct: 64 AADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLRPEL 123 Query: 165 AEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRR 224 VD++VVRELTG IYFG+PRG++ +G+ GFNT VY EI RIA VAF A+ RR Sbjct: 124 VRDVDILVVRELTGDIYFGQPRGLEVI-DGKRRGFNTMVYDEDEIRRIAHVAFRAAQGRR 182 Query: 225 GKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNN 284 +LCSVDKANVLE + LWR+ VT +A +YPDV LSHMYVDNAAMQL+R P QFD ++T N Sbjct: 183 KQLCSVDKANVLETTRLWREVVTEVARDYPDVRLSHMYVDNAAMQLIRAPAQFDVLLTGN 242 Query: 285 IFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAM 344 +FGDILSDEAS +TGSIGMLPSASL + G ++EPIHGSAPDIAGQDKANPLATILS AM Sbjct: 243 MFGDILSDEASQLTGSIGMLPSASLGE-GRAMYEPIHGSAPDIAGQDKANPLATILSVAM 301 Query: 345 LLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD 398 +L++ L E A+R+E AV L+ G RT DI + GT ++G K MG V+ +++ Sbjct: 302 MLRHSLNAEPWAQRVEAAVQRVLDQGLRTADIAAPGTPVIGTKAMGAAVVNALN 355 >4IWH-A nrPDB Length = 363 Score = 396 bits (1017), Expect = e-110, Method: Compositional matrix adjust. Identities = 200/357 (56%), Positives = 254/357 (71%), Gaps = 8/357 (2%) Query: 45 ITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAK 104 I +LPGDGIGPE+V+ A VL +F P+GGA + G PLP+ T++ AK Sbjct: 11 IAVLPGDGIGPEIVNEAVKVLNALDE----KFELEHAPVGGAGYEASGHPLPDATLALAK 66 Query: 105 ESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREV 164 E+DA+L GA+G +K+D+ E+ LRPE+ +L +R L++FAN RPA PQLVDAS LK E+ Sbjct: 67 EADAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPEL 126 Query: 165 AEGVDLMVVRELTGGIYFGEPRGIKTNENG----EEVGFNTEVYAAHEIDRIARVAFETA 220 G+D+++VREL G IYFG+PRG++ +G E GF+T Y+ E+ RIA VAF+ A Sbjct: 127 VAGLDILIVRELNGDIYFGQPRGVRAAPDGPFAGEREGFDTMRYSEPEVRRIAHVAFQAA 186 Query: 221 RKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 +KR KL SVDK+NVLE S WR + ++ EY DVELSHMYVDNAAMQL + PKQFD I Sbjct: 187 QKRAKKLLSVDKSNVLETSQFWRDVMIDVSKEYADVELSHMYVDNAAMQLAKAPKQFDVI 246 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 VT N+FGDILSDEASM+TGSIGMLPSASL + GL+EP HGSAPDIAG+ ANPLATIL Sbjct: 247 VTGNMFGDILSDEASMLTGSIGMLPSASLDKNNKGLYEPSHGSAPDIAGKGIANPLATIL 306 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 397 SAAMLL+Y L + A RIE AV L G+RTGDI + G + VG MG+ V+ ++ Sbjct: 307 SAAMLLRYSLNRAEQADRIERAVKTVLEQGYRTGDIATPGCRQVGTAAMGDAVVAAL 363 >1V5B-A nrPDB Length = 366 Score = 372 bits (954), Expect = e-103, Method: Compositional matrix adjust. Identities = 193/358 (53%), Positives = 247/358 (68%), Gaps = 2/358 (0%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETIS 101 + + +LPGDGIGPEV+ A VL+ +G E F IGGAA+D G PLPEET+ Sbjct: 2 KMKLAVLPGDGIGPEVMDAAIRVLKTVLDNDGHEAVFENALIGGAAIDEAGTPLPEETLD 61 Query: 102 AAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLK 161 + SDA+LLGA+GG KWD+N LRPEKGLL +R + +FANLRP L++AS LK Sbjct: 62 ICRRSDAILLGAVGGPKWDHNPASLRPEKGLLGLRKEMGLFANLRPVKAYATLLNASPLK 121 Query: 162 REVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETAR 221 RE E VDL++VRELTGG+YFG P + GE +T Y EI+RI AF+ A+ Sbjct: 122 RERVENVDLVIVRELTGGLYFGRPS--ERRGPGENEVVDTLAYTREEIERIIEKAFQLAQ 179 Query: 222 KRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIV 281 RR KL SVDKANVLE+S +WR+ A +YPDVELSHM VD+ AMQL+ +P QFD IV Sbjct: 180 IRRKKLASVDKANVLESSRMWREIAEETAKKYPDVELSHMLVDSTAMQLIANPGQFDVIV 239 Query: 282 TNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILS 341 T N+FGDILSD AS+ITGS+GMLPSASL G++EP+HGSAPDIAGQ KANPL T+LS Sbjct: 240 TENMFGDILSDLASVITGSLGMLPSASLRSDRFGMYEPVHGSAPDIAGQGKANPLGTVLS 299 Query: 342 AAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDS 399 AA++L+Y G EK A IE AV L +G+ TGD+ A K+V E+ + +++ +++ Sbjct: 300 AALMLRYSFGLEKEAAAIEKAVDDVLQDGYCTGDLQVANGKVVSTIELTDRLIEKLNN 357 >1CM7-A nrPDB Length = 363 Score = 365 bits (938), Expect = e-101, Method: Compositional matrix adjust. Identities = 187/359 (52%), Positives = 252/359 (70%), Gaps = 4/359 (1%) Query: 41 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETI 100 K Y I +LPGDGIGPEV++ A VL + + +GGAA+D G PLP T+ Sbjct: 3 KNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATV 62 Query: 101 SAAKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLVDAST 159 +++DAVL G++GG KW++ +PE+G LL +R K+F+NLRPA + L Sbjct: 63 EGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCP 122 Query: 160 LKREVA-EGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 218 L+ ++A G D++ VRELTGGIYFG+P+G + E F+TEVY EI+RIAR+AFE Sbjct: 123 LRADIAANGFDILCVRELTGGIYFGQPKG-REGSGQYEKAFDTEVYHRFEIERIARIAFE 181 Query: 219 TARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD 278 +ARKRR K+ S+DKANVL++SILWR+ V +A+EYPDVEL+HMY+DNA MQL++DP QFD Sbjct: 182 SARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQFD 241 Query: 279 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT 338 ++ +N+FGDILSDE +MITGS+GMLPSASL++ G GL+EP GSAPDIAG++ ANP+A Sbjct: 242 VLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQ 301 Query: 339 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 397 ILS A+LL+Y L + AA IE A+ AL G RTGD+ + G V EMG+ + + V Sbjct: 302 ILSLALLLRYSLDADDAACAIERAINRALEEGIRTGDL-ARGAAAVSTDEMGDIIARYV 359 >1CNZ-A nrPDB Length = 363 Score = 362 bits (928), Expect = e-100, Method: Compositional matrix adjust. Identities = 185/359 (51%), Positives = 249/359 (69%), Gaps = 4/359 (1%) Query: 41 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETI 100 K Y I +LPGDGIGPEV++ A V+ S + +GG A+D G PLP+ T+ Sbjct: 3 KNYHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATV 62 Query: 101 SAAKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLVDAST 159 +++DA+L G++GG KW+N +PE+G LL +R K+F+NLRPA + L Sbjct: 63 EGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCP 122 Query: 160 LKREVA-EGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 218 L+ ++A G D++ VRELTGGIYFG+P+G + E F+TEVY EI+RIAR+AFE Sbjct: 123 LRADIAANGFDILCVRELTGGIYFGQPKG-REGSGQYEKAFDTEVYHRFEIERIARIAFE 181 Query: 219 TARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD 278 +ARKRR K+ S+DKANVL++SILWR+ V +A YPDVEL+HMY+DNA MQL++DP QFD Sbjct: 182 SARKRRRKVTSIDKANVLQSSILWREIVNDVAKTYPDVELAHMYIDNATMQLIKDPSQFD 241 Query: 279 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT 338 ++ +N+FGDILSDE +MITGS+GMLPSASL++ G GL+EP GSAPDIAG++ ANP+A Sbjct: 242 VLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQ 301 Query: 339 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 397 ILS A+LL+Y L AA IE A+ AL G RTGD+ + G V EMG+ + + V Sbjct: 302 ILSLALLLRYSLDANDAATAIEQAINRALEEGVRTGDL-ARGAAAVSTDEMGDIIARYV 359 >1XAD-A nrPDB Length = 345 Score = 358 bits (919), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 182/323 (56%), Positives = 223/323 (69%), Gaps = 6/323 (1%) Query: 45 ITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAK 104 + +LPGDGIGPEV A VL+ EG+ + P GGAA+D G P PE T + Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVE 62 Query: 105 ESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREV 164 E++AVLLG++GG KWD N + LRPEKGLL IR L +FANLRP V L DAS LK+E Sbjct: 63 EAEAVLLGSVGGPKWDQNPRELRPEKGLLSIRKQLDLFANLRPVKVFESLSDASPLKKEY 122 Query: 165 AEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRR 224 + VD ++VRELTGGIYFGEPRG+ E +NTE Y+ E++R+ARVAFE ARKRR Sbjct: 123 IDNVDFVIVRELTGGIYFGEPRGMSEAE-----AWNTERYSKPEVERVARVAFEAARKRR 177 Query: 225 GKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNN 284 + SVDKANVLE WRK V + YPDV L H YVD AM LVR P +FD +VT N Sbjct: 178 KHVVSVDKANVLEVGEFWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGN 237 Query: 285 IFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAM 344 IFGDILSD AS++ GS+G+LPSASL P +FEP+HGSAPDIAG+ ANP A ILSAAM Sbjct: 238 IFGDILSDLASVLPGSLGLLPSASLGRGTP-VFEPVHGSAPDIAGKGIANPTAAILSAAM 296 Query: 345 LLKYGLGEEKAAKRIEDAVLVAL 367 +L++ G + A+++EDAV AL Sbjct: 297 MLEHAFGLVELARKVEDAVAKAL 319 >1IDM-A nrPDB Length = 343 Score = 346 bits (887), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 178/323 (55%), Positives = 222/323 (68%), Gaps = 8/323 (2%) Query: 45 ITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAK 104 + +LPGDGIGPEV A VL+ EG+ + P GGAA+D G P PE T + Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVE 62 Query: 105 ESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREV 164 E++AVLLG++GG KW +RPE+GLL +R + +FANLRPA V P L S LK E+ Sbjct: 63 EAEAVLLGSVGGPKWGTGS--VRPEQGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEI 120 Query: 165 AEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRR 224 A GVD+++VRELTGGIYFGEPRG+ E +NTE Y+ E++R+ARVAFE ARKRR Sbjct: 121 ARGVDVLIVRELTGGIYFGEPRGMSEAE-----AWNTERYSKPEVERVARVAFEAARKRR 175 Query: 225 GKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNN 284 + SVDKANVLE WRK V + YPDV L H YVD AM LVR P +FD +VT N Sbjct: 176 KHVVSVDKANVLEVGEFWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGN 235 Query: 285 IFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAM 344 IFGDILSD AS++ GS+G+LPSASL P +FEP+HGSAPDIAG+ ANP A ILSAAM Sbjct: 236 IFGDILSDLASVLPGSLGLLPSASLGRGTP-VFEPVHGSAPDIAGKGIANPTAAILSAAM 294 Query: 345 LLKYGLGEEKAAKRIEDAVLVAL 367 +L++ G + A+++EDAV AL Sbjct: 295 MLEHAFGLVELARKVEDAVAKAL 317 >3VMJ-A nrPDB Length = 375 Score = 343 bits (880), Expect = 9e-95, Method: Compositional matrix adjust. Identities = 172/342 (50%), Positives = 242/342 (70%), Gaps = 3/342 (0%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 Y I +L GDGIGPEV++ A+ VL+ + G+ + E +GG A+D G PLPE T+ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLVDASTLK 161 + +DA+L G++GG KW+ + +PE+G LL +R ++F NLRPA + L S L+ Sbjct: 74 CEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHMSPLR 133 Query: 162 REV-AEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA 220 ++ A G D++ VRELTGGIYFG+P+G + E E F+T Y+ EI RIAR+AFE A Sbjct: 134 SDISARGFDVLCVRELTGGIYFGKPKG-RQGEGESEEAFDTMRYSRREISRIARIAFEAA 192 Query: 221 RKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 R RR K+ SVDKANVL S+LWR+ V +A ++PDVEL H+Y+DNA MQL+R P +FD + Sbjct: 193 RGRRKKVTSVDKANVLACSVLWRQVVEEVAVDFPDVELEHIYIDNATMQLLRRPDEFDVM 252 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 + +N+FGDILSDE +M+TGS+G+L SAS++ +G GLFEP GSAPDIAG+ ANP+A IL Sbjct: 253 LCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGLFEPAGGSAPDIAGKGIANPIAQIL 312 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTK 382 SAA++L++ L +E+AA IE AV ALN+G+ TG++ S+ + Sbjct: 313 SAALMLRHSLKQEEAASAIERAVTKALNSGYLTGELLSSDQR 354 >1VLC-A nrPDB Length = 366 Score = 340 bits (872), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 182/356 (51%), Positives = 238/356 (66%), Gaps = 9/356 (2%) Query: 45 ITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAK 104 I +LPGDGIGPEVV A VL+ G F IGG A+D G PLPEET Sbjct: 15 IAVLPGDGIGPEVVREALKVLEVVEKKTGKTFEKVFGHIGGDAIDRFGEPLPEETKKICL 74 Query: 105 ESDAVLLGAIGGYKWDNNEKHLRPE-KGLLQIRAALKVFANLRPATVLPQLVDASTLKRE 163 E+DA+ LG++GG KWD+ RPE GLL +R L ++AN+RP V LV S LK + Sbjct: 75 EADAIFLGSVGGPKWDDLPPEKRPEIGGLLALRKMLNLYANIRPIKVYRSLVHVSPLKEK 134 Query: 164 V-AEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARK 222 V GVDL+ VREL+ G+Y+G+PRG+ EE GF+T +Y ++RIAR AFE A+ Sbjct: 135 VIGSGVDLVTVRELSYGVYYGQPRGLD-----EEKGFDTMIYDRKTVERIARTAFEIAKN 189 Query: 223 RRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVT 282 RR K+ SVDKANVL +S+LWRK V +A EYPDVEL+H+YVDNAAMQL+ P QFD I+T Sbjct: 190 RRKKVTSVDKANVLYSSMLWRKVVNEVAREYPDVELTHIYVDNAAMQLILKPSQFDVILT 249 Query: 283 NNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSA 342 N+FGDILSDE++ + GS+G+LPSAS D L+EP GSAPDIAG++ ANP+A ILS Sbjct: 250 TNMFGDILSDESAALPGSLGLLPSASFGDK--NLYEPAGGSAPDIAGKNIANPIAQILSL 307 Query: 343 AMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD 398 AM+L++ G + A++IE AV + + G+RT DI K V +MG+ + K ++ Sbjct: 308 AMMLEHSFGMVEEARKIERAVELVIEEGYRTRDIAEDPEKAVSTSQMGDLICKKLE 363 >3VML-A nrPDB Length = 375 Score = 338 bits (866), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 170/342 (49%), Positives = 242/342 (70%), Gaps = 3/342 (0%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 Y I +L GDGIGPEV++ A+ VL+ + G+ + E +GG A+D G PLPE T+ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLVDASTLK 161 + +DAVL G++GG KW++ + +PE+G LL +R ++F N+RPA + P L S L+ Sbjct: 74 CEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPLR 133 Query: 162 REVAE-GVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA 220 +++E G D++ VRELTGGIYFG+P+G + E E F+T Y+ EI RIA++AFE+A Sbjct: 134 SDISEKGFDILCVRELTGGIYFGKPKG-RQGEGENEEAFDTMRYSRKEIRRIAKIAFESA 192 Query: 221 RKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 + RR K+ SVDKANVL S+LWR+ V +A +YPDVEL H+Y+DNA MQL+R P +FD + Sbjct: 193 QGRRKKVTSVDKANVLACSVLWREVVEEVAKDYPDVELEHIYIDNATMQLLRRPNEFDVM 252 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 + +N+FGDI+SDE +M+TGS+G+L S S++ G G++EP GSAPDIAGQ ANP+A IL Sbjct: 253 LCSNLFGDIVSDEIAMLTGSMGLLASISMNSQGFGMYEPAGGSAPDIAGQGIANPVAQIL 312 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTK 382 SAA+LL++ L E AA IE AV ALN+G+ TG++ S+ + Sbjct: 313 SAALLLRHSLKLEDAALAIEAAVSKALNSGYLTGELLSSDQR 354 >3VMK-A nrPDB Length = 375 Score = 332 bits (851), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 170/359 (47%), Positives = 247/359 (68%), Gaps = 5/359 (1%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 Y I +L GDGIGPEV++ A+ VL + + E +GGAA+D G PLPE T+ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLAAVEKRFDLSIEYSEYDVGGAAIDNHGCPLPEATLKG 73 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLVDASTLK 161 + +DAVL G++GG KW++ + +PE+G LL +R ++F N+RPA + P L S L+ Sbjct: 74 CEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPLR 133 Query: 162 REVAE-GVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA 220 +++E G D++ VRELTGGIYFG+P+G + E E F+T Y+ EI RIA++AFE+A Sbjct: 134 SDISEKGFDILCVRELTGGIYFGKPKG-RQGEGENEEAFDTMRYSRKEIRRIAKIAFESA 192 Query: 221 RKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 + RR K+ SVDKANVL S+LWR+ V +A +YPDVEL H+Y+DNA MQL+R P +FD + Sbjct: 193 QGRRKKVTSVDKANVLACSVLWREVVEEVAKDYPDVELEHIYIDNATMQLLRRPNEFDVM 252 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 + +N+FGDI+SDE +M+TGS+G+L S S++ G G++EP GSAPDIAGQ ANP+A IL Sbjct: 253 LCSNLFGDIVSDEIAMLTGSMGLLASISMNSQGFGMYEPAGGSAPDIAGQGIANPVAQIL 312 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAG--TKLVGCKEMGEEVLKSV 397 SAA+LL++ L E AA IE AV AL++G+ T ++ A ++ +MG+ + +++ Sbjct: 313 SAALLLRHSLKLEDAALAIEAAVSKALSDGYLTCELLPASERSQAKSTSQMGDYIAQAI 371 >3UDO-A nrPDB Length = 361 Score = 315 bits (806), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 177/368 (48%), Positives = 242/368 (65%), Gaps = 13/368 (3%) Query: 37 SPGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLP 96 S K Y + +L GDGIGP V+ A +L F E IGGA++D GV L Sbjct: 1 SNAMKTYKVAVLAGDGIGPLVMKEALKILTFIAQKYNFSFELNEAKIGGASIDAYGVALS 60 Query: 97 EETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLV 155 +ET+ ++SDA+L G++GG KWDN RPE+ LL +R +FANLRP + L Sbjct: 61 DETLKLCEQSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLT 120 Query: 156 DASTLKREVAE-GVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIAR 214 AS LK E+ + GVD++ VRELTGGIYFG+ + G+E ++TE+Y EI+RIAR Sbjct: 121 HASPLKNEIIQKGVDILCVRELTGGIYFGK------QDLGKESAYDTEIYTKKEIERIAR 174 Query: 215 VAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDP 274 +AFE+AR R+ K+ +DKANVL +SILWR+ V +A +Y D+ L +MYVDNAAMQ+V++P Sbjct: 175 IAFESARIRKKKVHLIDKANVLASSILWREVVANVAKDYQDINLEYMYVDNAAMQIVKNP 234 Query: 275 KQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKAN 334 FD ++ +N+FGDILSDE + I GS+G+L SASL+D G GL+EP GSAPDIA + AN Sbjct: 235 SIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNIAN 294 Query: 335 PLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGE--- 391 P+A ILSAA++LKY EE+AA+ IE+A+ +AL G T D+ + EMG+ Sbjct: 295 PIAQILSAALMLKYSFKEEQAAQDIENAISLALAQGKMTKDL--NAKSYLNTDEMGDCIL 352 Query: 392 EVLKSVDS 399 E+LK D+ Sbjct: 353 EILKENDN 360 >3ASJ-A nrPDB Length = 334 Score = 189 bits (479), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 135/340 (39%), Positives = 180/340 (52%), Gaps = 34/340 (10%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 Y I L+ GDGIG EV+ A+ VL+ G + F E G + G +PEET+ Sbjct: 3 YRICLIEGDGIGHEVIPAARRVLEATG----LPLEFVEAEAGWETFERRGTSVPEETVEK 58 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKGLL----QIRAALKVFANLRPATVLPQLVDAS 158 A L GA R G +R L ++AN+RPA P V S Sbjct: 59 ILSCHATLFGA--------ATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRP--VPGS 108 Query: 159 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 218 GVDL++VRE T G+Y + R +V V + +RI R A Sbjct: 109 R------PGVDLVIVRENTEGLYVEQERRYL------DVAIADAVISKKASERIGRAALR 156 Query: 219 TARKR-RGKLCSVDKANVLEASI-LWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQ 276 A R R L KANVL + L+ V +A ++P V + + VDN AMQLV P++ Sbjct: 157 IAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPER 216 Query: 277 FDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPL 336 FD IVT N+ GDILSD A+ + G +G+ PS ++ D+ +FEP+HGSAPDIAG+ ANP Sbjct: 217 FDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDT-TAVFEPVHGSAPDIAGKGIANPT 275 Query: 337 ATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDI 376 A ILSAAM+L Y LGE++AAKR+E AV + L G RT D+ Sbjct: 276 AAILSAAMMLDY-LGEKEAAKRVEKAVDLVLERGPRTPDL 314 >2G4O-A nrPDB Length = 337 Score = 188 bits (477), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 130/325 (40%), Positives = 184/325 (56%), Gaps = 22/325 (6%) Query: 45 ITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAK 104 + ++ GDGIGPEV + A VL + GV+ ++ G G LP+ ++ + Sbjct: 4 LAIIAGDGIGPEVTAEAVKVLDAV--VPGVQKTSYDL--GARRFHATGEVLPDSVVAELR 59 Query: 105 ESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREV 164 DA+LLGAIG + + LL++R L NLRPA + P + AS L Sbjct: 60 NHDAILLGAIGDPSVPSG---VLERGLLLRLRFELDHHINLRPARLYPGV--ASPLSGN- 113 Query: 165 AEGVDLMVVRELTGGIYFGEPRGIKT---NENGEEVGFNTEVYAAHEIDRIARVAFETAR 221 G+D +VVRE T G Y G I+ NE EV NT A + R+ AFE AR Sbjct: 114 -PGIDFVVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNT----AFGVRRVVADAFERAR 168 Query: 222 KRRGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 +RR L V K NVL A LW + V + YPDVE+++ +VD A + ++ DP +FD I Sbjct: 169 RRRKHLTLVHKTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVI 228 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASL--SDSGPGLFEPIHGSAPDIAGQDKANPLAT 338 VT+N+FGDI++D A+ + G IG+ S ++ + + P +FEP+HGSAPDIAGQ A+P A Sbjct: 229 VTDNLFGDIITDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAA 288 Query: 339 ILSAAMLLKYGLGEEKAAKRIEDAV 363 I+S A+LL + LGE AA R++ AV Sbjct: 289 IMSVALLLSH-LGEHDAAARVDRAV 312 >3FMX-X nrPDB Length = 364 Score = 180 bits (456), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 118/341 (34%), Positives = 178/341 (52%), Gaps = 14/341 (4%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLV-GVPLPEETIS 101 + I +PGDGIG EV+ VL+ A G+ F L G +P++ Sbjct: 6 FRIAAIPGDGIGLEVLPEGIRVLEAAALKHGLALEFDTFEWASCDYYLQHGKMMPDDWAE 65 Query: 102 AAKESDAVLLGAIGGYKW-DNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTL 160 K+ DA+ GA+G W D H+ LL+ R + N+RP + P V + Sbjct: 66 QLKQYDAIYFGAVG---WPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPG-VPCALA 121 Query: 161 KREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA 220 R+V + +D +VVRE T G Y GI E+ ++ +DRI + AF+ A Sbjct: 122 NRKVGD-IDFVVVRENTEGEY-SSLGGIMFENTENEIVIQESIFTRRGVDRILKYAFDLA 179 Query: 221 RKR-RGKLCSVDKANVLEASI-LWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD 278 KR R + S K+N + S+ W KR A+A+ YP V ++D + V P++FD Sbjct: 180 EKRERKHVTSATKSNGMAISMPYWDKRTEAMAAHYPHVSWDKQHIDILCARFVLQPERFD 239 Query: 279 TIVTNNIFGDILSDEASMITGSIGMLPSASLS--DSGPGLFEPIHGSAPDIAGQDKANPL 336 +V +N+FGDILSD G+IG+ PSA+L+ + P LFEP+HGSAPDI G++ ANP+ Sbjct: 240 VVVASNLFGDILSDLGPACAGTIGIAPSANLNPERNFPSLFEPVHGSAPDIFGKNIANPI 299 Query: 337 ATILSAAMLLKY-GLGEEKAAKRIEDAVLVALNNGFRTGDI 376 A I S A++L++ G G+E+ +R D +L A+ G + Sbjct: 300 AMIWSGALMLEFLGQGDER-YQRAHDDMLNAIERVIADGSV 339 >1WPW-A nrPDB Length = 336 Score = 180 bits (456), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 120/331 (36%), Positives = 184/331 (55%), Gaps = 34/331 (10%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 +T+ L+ GDGIGPE+VS +K +L + L + + E+ G AL G LP++++ Sbjct: 2 FTVALIQGDGIGPEIVSKSKRILAKINELYSLPIEYIEVEAGDRALARYGEALPKDSLKI 61 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKR 162 ++D +L G +G D ++++R ++AN+RPA +P +D Sbjct: 62 IDKADIILKGPVGESAADV----------VVKLRQIYDMYANIRPAKSIPG-IDTKY--- 107 Query: 163 EVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARK 222 VD+++VRE T +Y G + +G VG A E RIA+V A + Sbjct: 108 ---GNVDILIVRENTEDLYKGFEHIV---SDGVAVGMKIITRFASE--RIAKVGLNFALR 159 Query: 223 RRGKLCSVDKANVLEAS--ILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 RR K+ V KANV+ + + + L + VE S MYVD AA LVR+P+ FD I Sbjct: 160 RRKKVTCVHKANVMRITDGLFAEACRSVLKGK---VEYSEMYVDAAAANLVRNPQMFDVI 216 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 VT N++GDILSDEAS I GS+G+ PSA++ D LFEP+HG+A DIAG++ NP A +L Sbjct: 217 VTENVYGDILSDEASQIAGSLGIAPSANIGDK-KALFEPVHGAAFDIAGKNIGNPTAFLL 275 Query: 341 SAAMLLK--YGLGEE----KAAKRIEDAVLV 365 S +M+ + Y L + KA++ +E+A+ + Sbjct: 276 SVSMMYERMYELSNDDRYIKASRALENAIYL 306 >4Y1P-A nrPDB Length = 337 Score = 176 bits (447), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 128/370 (34%), Positives = 191/370 (51%), Gaps = 47/370 (12%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 + + L+ GDGIGPEVVS +K +L + + + E+ G + G LP++++ Sbjct: 3 FVVALIQGDGIGPEVVSKSKTILARLNEKFSLPIEYIEVEAGDTTKNKFGDALPKDSLRV 62 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKR 162 +++D +L G +G D ++++R ++ANLRPA LP L + Sbjct: 63 IEKADMILKGPVGETAADV----------VVKLRLMYDLYANLRPAKSLPGLENKFG--- 109 Query: 163 EVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARK 222 VD++VVRE T +Y G I +G VG AA RIA+VA A + Sbjct: 110 ----DVDILVVRENTEDLYKGLEHVI---SDGVTVGIKVITRAAST--RIAQVALNQALR 160 Query: 223 RRGKLCSVDKANVLEAS--ILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 R+ K+ V K+NV+ + + L + VE S MYVD AA LVR+P+ FD I Sbjct: 161 RKKKVVCVHKSNVMRITDGLFAESCRNVLKGK---VEYSEMYVDAAAANLVRNPQAFDVI 217 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 VT N +GDILSDEA I GS+G+ PSA++ D LFEP+HG+A DIAG++ ANP A +L Sbjct: 218 VTENTYGDILSDEAGQIAGSLGISPSANIGDR-KSLFEPVHGAAFDIAGKNIANPTAFLL 276 Query: 341 SAAMLLKY------GLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKL---VGCKEMGE 391 S M+L + AAK + DA+ +YS G L VG + Sbjct: 277 SVGMMLDRMQELSGDIRYNNAAKSLRDAIY----------SVYSEGKYLTPDVGGSSTTD 326 Query: 392 EVLKSVDSQV 401 E++ ++ S++ Sbjct: 327 EMISAIRSKI 336 >5HN5-A nrPDB Length = 353 Score = 168 bits (426), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 119/313 (38%), Positives = 168/313 (53%), Gaps = 44/313 (14%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGA-ALDLVGVPLPEETIS 101 Y + ++PGDGIGPEV+ A VL+ V F + E GG G P+ EE + Sbjct: 2 YRVAVIPGDGIGPEVIDGAVRVLKAVTGR--VRFEYYE---GGVDVFQECGSPIREEDLE 56 Query: 102 AAKESDAVLLGA------IGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLV 155 + SDAVL GA + GY+ +L +R L ++ANLR ++P L Sbjct: 57 EIRRSDAVLFGATTTPFDLPGYR-----------SLILTLRKELGLYANLR---IIPDL- 101 Query: 156 DASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARV 215 G ++++VRE + G+YFG I NG V + + +RIAR Sbjct: 102 ---------RTGREIVIVRENSEGLYFG----IGAVVNGRAV--DVRLITREGAERIARF 146 Query: 216 AFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPK 275 A E A+ R + V KANVL +R+ V +A E VE+ +D+ ++LVR+P Sbjct: 147 AVEQAKARGSFITFVHKANVLTGDKFFRRIVREVAGE-EGVEVRDAIIDSFTIKLVRNPW 205 Query: 276 QFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANP 335 + I++ N+FGDILSD A++ GSIG++PS + D G LFEP+HGSAPDIAG+ ANP Sbjct: 206 EHGVILSENLFGDILSDLATVHAGSIGIVPSGNYGD-GIALFEPVHGSAPDIAGKGIANP 264 Query: 336 LATILSAAMLLKY 348 + ILS AMLL Y Sbjct: 265 IGAILSGAMLLDY 277 >2D1C-A nrPDB Length = 496 Score = 167 bits (423), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 126/351 (35%), Positives = 186/351 (52%), Gaps = 36/351 (10%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVP--LPEET 99 R IT++PGDGIGPE V VL+ A + + + RE GA++ G+ +P+ET Sbjct: 19 RKLITVIPGDGIGPECVEATLKVLEAAKA--PLAYEVRE---AGASVFRRGIASGVPQET 73 Query: 100 ISAAKESDAVLLGAIG---GYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVD 156 I + +++ VL G + GY EK + +R + +AN+RP P + Sbjct: 74 IESIRKTRVVLKGPLETPVGY----GEKSAN-----VTLRKLFETYANVRPVREFPNVPT 124 Query: 157 ASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVA 216 G+DL+VVRE +Y G + V ++ + ++I R A Sbjct: 125 PYA-----GRGIDLVVVRENVEDLYAG-----IEHMQTPSVAQTLKLISWKGSEKIVRFA 174 Query: 217 FETARKR-RGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDP 274 FE AR R K+ K+N+++ A ++ +A EYPD+E H+ VDNAA QLV+ P Sbjct: 175 FELARAEGRKKVHCATKSNIMKLAEGTLKRAFEQVAQEYPDIEAVHIIVDNAAHQLVKRP 234 Query: 275 KQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKAN 334 +QF+ IVT N+ GDILSD S + G +G PSA++ + +FE +HGSAP AG++ N Sbjct: 235 EQFEVIVTTNMNGDILSDLTSGLIGGLGFAPSANIGNE-VAIFEAVHGSAPKYAGKNVIN 293 Query: 335 PLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNG-FRTGDI--YSAGTK 382 P A +LSA M+L+Y L E A IE+A+L L G TGD+ Y G K Sbjct: 294 PTAVLLSAVMMLRY-LEEFATADLIENALLYTLEEGRVLTGDVVGYDRGAK 343 >3TY3-A nrPDB Length = 366 Score = 154 bits (390), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 108/348 (31%), Positives = 181/348 (52%), Gaps = 34/348 (9%) Query: 41 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETI 100 +R + L+P DGIG EVV A+ +++ + ++F+F ++ G + G LPE T+ Sbjct: 9 RRIVLGLIPADGIGKEVVPAARRLMENLPAKHKLKFDFIDLDAGWGTFERTGKALPERTV 68 Query: 101 SAAK-ESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAST 159 K E +A L GA+ K ++ +R + ++AN+RP + Sbjct: 69 ERLKTECNAALFGAV----QSPTHKVAGYSSPIVALRKKMGLYANVRPV---------KS 115 Query: 160 LKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFET 219 L + VDL++VRE T +Y E R ++ N G+ V + +I ++AFE Sbjct: 116 LDGAKGKPVDLVIVRENTECLYVKEERMVQ-NTPGKRVAEAIRRISEEASTKIGKMAFEI 174 Query: 220 ARKR-------------RGKLCSVDKANVLEASI-LWR---KRVTALASEYPDVELSHMY 262 A+ R + + + K+NV+ + L+R + +L Y + + Sbjct: 175 AKSRQKIRESGTYSIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYASINVDEQI 234 Query: 263 VDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHG 322 VD+ +L R+P+ FD +V N++GDILSD A+ + GS+G++PSA++ D+ + EP+HG Sbjct: 235 VDSMVYRLFREPECFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGDNFV-MSEPVHG 293 Query: 323 SAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNG 370 SAPDIAG+ ANP+AT S A++L++ +G + AA I AV L G Sbjct: 294 SAPDIAGRGIANPVATFRSVALMLEF-MGHQDAAADIYTAVDKVLTEG 340 >5YVT-A nrPDB Length = 339 Score = 152 bits (385), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 114/360 (31%), Positives = 177/360 (49%), Gaps = 36/360 (10%) Query: 44 TITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETI--- 100 T+TL+PGDGIGPE+ + + F+ + PI ++ + P Sbjct: 6 TVTLIPGDGIGPEISAAVMKI-----------FDAAKAPIQWEERNVTAIQGPGGKWMIP 54 Query: 101 SAAKES-DAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAST 159 S AKES D +G G K H P LL +R ++AN+RP + T Sbjct: 55 SEAKESMDKNKMGLKGPLKTPIAAGH--PSMNLL-LRKTFDLYANVRPCVSIEGYKTPYT 111 Query: 160 LKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFET 219 V+++ +RE T G Y G I + V + ++ RIA AFE Sbjct: 112 -------DVNIVTIRENTEGEYSGIEHVIV-----DGVVQSIKLITEGASKRIAEFAFEY 159 Query: 220 ARK-RRGKLCSVDKANVLEASI-LWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQF 277 AR R + +V KAN++ S L+ ++ +A D++ + MY+D + +V+DP QF Sbjct: 160 ARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQF 219 Query: 278 DTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLA 337 D +V N++GDILSD + + G +G+ PS ++ +G +FE +HG+APDIAG+D ANP A Sbjct: 220 DVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTA 279 Query: 338 TILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 397 +LSA M+L++ +G A RIE A + +G K C + EE+ + V Sbjct: 280 LLLSAVMMLRH-MGLFDHAARIEAACFATIKDGKSLTKDLGGNAK---CSDFTEEICRRV 335 >3BLV-B nrPDB Length = 354 Score = 138 bits (347), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 112/363 (30%), Positives = 182/363 (50%), Gaps = 56/363 (15%) Query: 37 SPGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGV--- 93 +P +YT++ + GDGIGPE+ K + A +PI + D+ + Sbjct: 16 NPSTGKYTVSFIEGDGIGPEISKSVKKIFSAA-----------NVPIEWESCDVSPIFVN 64 Query: 94 ---PLPEETISAAKESDAVLLGAIG-----GYKWDNNEKHLRPEKGLLQIRAALKVFANL 145 +P+ + + ++ L G + G++ N L +R +FAN+ Sbjct: 65 GLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLN-----------LTLRKTFGLFANV 113 Query: 146 RPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYA 205 RPA + + E VDL+++RE T G Y G + V + ++ Sbjct: 114 RPAKSIEGF-------KTTYENVDLVLIRENTEGEYSGIEHIVCPG-----VVQSIKLIT 161 Query: 206 AHEIDRIARVAFETARK-RRGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYV 263 +R+ R AFE AR R ++ V K+ + A L+ L+ EYPD+ L + Sbjct: 162 RDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELI 221 Query: 264 DNAAMQLVRDPKQF-DTI-VTNNIFGDILSD-EASMITGSIGMLPSASLSDSGPGLFEPI 320 DN+ +++V +P + D + V N++GDILSD + + GS+G+ PSA++ +FE + Sbjct: 222 DNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHK-ISIFEAV 280 Query: 321 HGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNG--FRTGDIYS 378 HGSAPDIAGQDKANP A +LS+ M+L + +G A +I++AVL + +G RTGD+ Sbjct: 281 HGSAPDIAGQDKANPTALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDL-- 337 Query: 379 AGT 381 AGT Sbjct: 338 AGT 340 >2IV0-A nrPDB Length = 412 Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 126/400 (31%), Positives = 191/400 (47%), Gaps = 63/400 (15%) Query: 45 ITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAK 104 I GDGIG +VV A VL A G E + ++ G A L G LP++T++A K Sbjct: 30 IPYFEGDGIGKDVVPAAIRVLDAAADKIGKEVVWFQVYAGEDAYKLYGNYLPDDTLNAIK 89 Query: 105 ESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAST 159 E L G + GGY+ N + IR L ++AN+RP L + S Sbjct: 90 EFRVALKGPLTTPVGGGYRSLN-----------VTIRQVLDLYANVRPVYYLKGV--PSP 136 Query: 160 LKREVAEGVDLMVVRELTGGIYFG--EPRGIK---------TNENG----EEVGFNTEVY 204 +K E V+ ++ RE T +Y G PRG + NE G E+ G + Sbjct: 137 IKH--PEKVNFVIFRENTEDVYAGIEWPRGSEEALKLIRFLKNEFGVTIREDSGIGIKPI 194 Query: 205 AAHEIDRIARVAFETA-RKRRGKLCSVDKANVLE----ASILWRKRVTALA-SEY--PDV 256 + R+ R+A A R + V K N+++ A W V EY + Sbjct: 195 SEFATKRLVRMAIRYAIENNRKSVTLVHKGNIMKYTEGAFRDWGYEVAKQEFGEYCITED 254 Query: 257 ELSHMY---------------VDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSI 301 EL Y DN Q++ ++D I N+ GD LSD A+ + G + Sbjct: 255 ELWDKYGGKQPEGKIVVKDRIADNMFQQILTRTDEYDVIALPNLNGDYLSDAAAALIGGL 314 Query: 302 GMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIED 361 G+ P +++ D G G+FEP+HGSAP AGQ+K NP A IL+ A++ +Y +G + A++ I+ Sbjct: 315 GIAPGSNIGD-GIGVFEPVHGSAPKYAGQNKVNPTAEILTGALMFEY-IGWKDASEMIKK 372 Query: 362 AVLVALNNGFRTGDIYS--AGTKLVGCKEMGEEVLKSVDS 399 AV + +++G T DI+ GTK VG +E E V++++ S Sbjct: 373 AVEMTISSGIVTYDIHRHMGGTK-VGTREFAEAVVENLQS 411 >2E5M-A nrPDB Length = 409 Score = 135 bits (340), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 123/406 (30%), Positives = 194/406 (47%), Gaps = 73/406 (17%) Query: 44 TITLLPGDGIGPEVVSIAKNVLQQA-----GSLEGVEFNFREMPIGGAALDLVGVPLPEE 98 I + GDGIGPE+ + A V+ +A GS E + E+ G A LV P+E Sbjct: 26 VILYIEGDGIGPEITNAAIKVINKAVERAYGS--SREIKWLEVYAGEKAEKLVNDRFPKE 83 Query: 99 TISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQ 153 T + VL G + G+K N + IR L ++AN+RP + Sbjct: 84 TQEMLLKYRVVLKGPLETPIGKGWKSVN-----------VAIRLMLDLYANIRPVKYIEG 132 Query: 154 LVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEE----------------- 196 L S LK E VD+++ RE T +Y RGI+ N EE Sbjct: 133 L--ESPLKH--PEKVDMIIFRENTDDLY----RGIEYPFNSEEAKKIRDFLRKELKVEIE 184 Query: 197 --VGFNTEVYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLEASI-LWRKRVTALA-S 251 G +V + ++ RI R+A + A +R K+ + K NV++ + +R+ +A Sbjct: 185 DDTGIGIKVMSKYKTQRITRLAIQYAIEHKRKKVTIMHKGNVMKYTEGAFREWAYEVALK 244 Query: 252 EYPD-----------------VELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEA 294 EY D + L+ DN Q++ P+++D I+ N+ GD +SD A Sbjct: 245 EYRDFIVTEEEINQGKPDQGKIILNDRIADNMFQQIIIRPEEYDIILAPNVNGDYISDAA 304 Query: 295 SMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEK 354 + G+IGML A++ D G G+FE IHG+AP AG++ ANP I + ++L++ +G + Sbjct: 305 GALIGNIGMLGGANIGDEG-GMFEAIHGTAPKYAGKNVANPTGIIKAGELMLRW-MGWNE 362 Query: 355 AAKRIEDAVLVALNNGFRTGDIYS-AGTKLVGCKEMGEEVLKSVDS 399 AA IE A+ +A+ + T DI G K +G KE +E++K +D+ Sbjct: 363 AADLIEKAINMAIRDKKVTQDIARFMGVKALGTKEYADELIKIMDT 408 >5GRH-B nrPDB Length = 354 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 100/350 (28%), Positives = 170/350 (48%), Gaps = 42/350 (12%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETIS 101 R+T+T++PGDGIGPE++ K+V + A V +F E+ + A D + I Sbjct: 15 RHTVTMIPGDGIGPELMLHVKSVFRHAC----VPVDFEEVHVSSNA-DEEDI---RNAIM 66 Query: 102 AAKESDAVLLGAIG-------GYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQL 154 A + + L G I +K NN +R +L ++AN+ LP + Sbjct: 67 AIRRNRVALKGNIETNHNLPPSHKSRNN-----------ILRTSLDLYANVIHCKSLPGV 115 Query: 155 VDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIAR 214 V + +D+++VRE T G Y +E+ V + ++ + RIA Sbjct: 116 VTRH-------KDIDILIVRENTEGEYSS-----LEHESVAGVVESLKIITKAKSLRIAE 163 Query: 215 VAFETARKR-RGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYVDNAAMQLVR 272 AF+ A++ R K+ +V KAN+++ L+ + +A+ YP + +M VDN MQLV Sbjct: 164 YAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVS 223 Query: 273 DPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDK 332 P+QFD +V N++G+I+++ + + G G++ A+ + IA ++ Sbjct: 224 RPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNI 283 Query: 333 ANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNN-GFRTGDIYSAGT 381 ANP AT+L++ M+L + L A I AVL +++N T DI GT Sbjct: 284 ANPTATLLASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQGT 332 >3BLX-A nrPDB Length = 349 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 102/341 (29%), Positives = 167/341 (48%), Gaps = 41/341 (12%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPE---E 98 R+T+TL+PGDG+G E+ + + F +PI +++ E E Sbjct: 17 RFTVTLIPGDGVGKEITDSVRTI-----------FEAENIPIDWETINIKQTDHKEGVYE 65 Query: 99 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS 158 + + K + L G W + +R L ++AN+ L Sbjct: 66 AVESLKRNKIGLKGL-----WHTPADQTGHGSLNVALRKQLDIYANVALFKSL------K 114 Query: 159 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 218 +K + + +DL+V+RE T G + G +E+ V + +V + +RIAR AF+ Sbjct: 115 GVKTRIPD-IDLIVIRENTEGEFSG-----LEHESVPGVVESLKVMTRPKTERIARFAFD 168 Query: 219 TARK-RRGKLCSVDKANVLE-ASILWRKRVTALAS-EYPDVELSHMYVDNAAMQLVRDPK 275 A+K R + +V KAN+++ L+R +T + EYPD+++S + VDNA+MQ V P Sbjct: 169 FAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPH 228 Query: 276 QFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAP---DIAGQDK 332 QFD +VT +++G IL + + + G G++ A+ +FEP GS DI GQ+ Sbjct: 229 QFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRD-YAVFEP--GSRHVGLDIKGQNV 285 Query: 333 ANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRT 373 ANP A ILS+ ++L + LG + A RI AV + G T Sbjct: 286 ANPTAMILSSTLMLNH-LGLNEYATRISKAVHETIAEGKHT 325 >1XGV-A nrPDB Length = 435 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 106/406 (26%), Positives = 174/406 (42%), Gaps = 71/406 (17%) Query: 44 TITLLPGDGIGPEVVSIAKNVLQQA------GSLEGVEFNFREMPIGGAALDLVGVPLPE 97 + + GDG+GPEVV A V+ A GS V + E+ G A + G LP+ Sbjct: 37 VVAFIRGDGVGPEVVESALKVVDAAVKKVYGGSRRIV---WWELLAGHLAREKCGELLPK 93 Query: 98 ETISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLP 152 T+ + + L G + GY+ N + IR AL ++AN+RP Sbjct: 94 ATLEGIRLARVALKGPLETPVGTGYRSLN-----------VAIRQALDLYANIRPVRYYG 142 Query: 153 QLVDASTLKREVAEGVDLMVVRELTGGIYFG-----------EPRGIKTNENG----EEV 197 Q + A+ VD+++ RE T +Y G R E G E+ Sbjct: 143 Q-----PAPHKYADRVDMVIFRENTEDVYAGIEWPHDSPEAARIRRFLAEEFGISIREDA 197 Query: 198 GFNTEVYAAHEIDRIARVAFETARKRRGKLCSV-DKANVLE----ASILW---------R 243 G + + R+ A E A + + ++ K N+++ A + W R Sbjct: 198 GIGVKPISRFATRRLMERALEWALRNGNTVVTIMHKGNIMKYTEGAFMRWAYEVALEKFR 257 Query: 244 KRVTA---LASEYPDVE------LSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEA 294 + V + +Y V ++ DN Q++ P + IV N+ GD +SD A Sbjct: 258 EHVVTEQEVQEKYGGVRPEGKILVNDRIADNMLQQIITRPWDYQVIVAPNLNGDYISDAA 317 Query: 295 SMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEK 354 S + G IGM ++ D G + EP+HG+AP AG+D NP A ILSA++L+ +G + Sbjct: 318 SALVGGIGMAAGMNMGD-GIAVAEPVHGTAPKYAGKDLINPSAEILSASLLIGEFMGWRE 376 Query: 355 AAKRIEDAVLVALNNGFRTGDI--YSAGTKLVGCKEMGEEVLKSVD 398 +E A+ A+ + T D+ + G + + E E ++ +D Sbjct: 377 VKSIVEYAIRKAVQSKKVTQDLARHMPGVQPLRTSEYTETLIAYID 422 >1HQS-A nrPDB Length = 423 Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 109/424 (25%), Positives = 176/424 (41%), Gaps = 92/424 (21%) Query: 45 ITLLPGDGIGPEVVSIAKNVLQQA--GSLEG-VEFNFREMPIGGAALDLVGVPLPEETIS 101 I + GDG GP++ + A VL+ A + +G + ++E+ G A + G LP ET+ Sbjct: 22 IPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEVYAGEKAYNKTGEWLPAETLD 81 Query: 102 AAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVD 156 +E + G + GG + N + +R L +F LRP + Sbjct: 82 VIREYFIAIKGPLTTPVGGGIRSLN-----------VALRQELDLFVCLRPVRYFTGV-- 128 Query: 157 ASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEV------------------- 197 S +KR E D+++ RE T IY GI+ + EEV Sbjct: 129 PSPVKR--PEDTDMVIFRENTEDIY----AGIEYAKGSEEVQKLISFLQNELNVNKIRFP 182 Query: 198 ---GFNTEVYAAHEIDRIARVAFETARKR-RGKLCSVDKANVLE----ASILWRKRVTAL 249 G + + R+ R A + A + R + V K N+++ A W + Sbjct: 183 ETSGIGIKPVSEEGTSRLVRAAIDYAIEHGRKSVTLVHKGNIMKFTEGAFKNWGYELAE- 241 Query: 250 ASEYPDVELSHMYVDNAA--------------------------------MQLVRDPKQF 277 EY D + D A Q++ P +F Sbjct: 242 -KEYGDKVFTWAQYDRIAEEQGKDAANKAQSEAEAAGKIIIKDSIADIFLQQILTRPNEF 300 Query: 278 DTIVTNNIFGDILSDEASMITGSIGMLPSASLS-DSGPGLFEPIHGSAPDIAGQDKANPL 336 D + T N+ GD +SD + G IG+ P A+++ ++G +FE HG+AP AG DK NP Sbjct: 301 DVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLDKVNPS 360 Query: 337 ATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDI--YSAGTKLVGCKEMGEEVL 394 + ILS +LL++ LG +AA + ++ + + T D G V C E GEE++ Sbjct: 361 SVILSGVLLLEH-LGWNEAADLVIKSMEKTIASKVVTYDFARLMDGATEVKCSEFGEELI 419 Query: 395 KSVD 398 K++D Sbjct: 420 KNMD 423 >2D4V-A nrPDB Length = 429 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 109/395 (27%), Positives = 173/395 (43%), Gaps = 80/395 (20%) Query: 45 ITLLPGDGIGPEVVSIAKNVLQQA-GSLEG--VEFNFREMPIGGAALDLVG--VPLPEET 99 I + GDGIG +V ++V+ A + G + + E+ G A+ L G LP+ET Sbjct: 29 IPFIEGDGIGCDVTPAMRSVVDAAVAKVYGGQRQIAWMELFAGQKAVQLYGEGQYLPDET 88 Query: 100 ISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQL 154 ++A +E + G + GG + N + +R L ++ LRP + Sbjct: 89 MAAIREYKVAIKGPLETPVGGGIRSLN-----------VAMRQDLDLYVCLRPV----RY 133 Query: 155 VDASTLKREVAEGVDLMVVRELTGGIYFG--EPRGIKTNEN-----GEEVGFNTEVYAAH 207 + + E VD+++ RE + IY G P G E EE+G + Sbjct: 134 FEGTPSPMRHPEKVDMVIFRENSEDIYAGIEWPAGSPEAEKIIRFLREEMGVTKIRFPDS 193 Query: 208 EIDRIARVAFETARK--RR--------GK--LCSVDKANVLEAS---------------- 239 I V+ E + + RR GK + V K N+++ + Sbjct: 194 SAIGIKPVSTEGSERLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGGFRDWGYALAEREF 253 Query: 240 ----ILWRKRVTALASE------------YPDVEL--SHMYVDNAAMQLVRDPKQFDTIV 281 WR++ +E D +L + DN Q++ P+ + + Sbjct: 254 AGRVFTWRQKAAISKAEGKAAGQKAEQQAIADGKLIIKDVIADNFLQQILLRPEDYSVVA 313 Query: 282 TNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILS 341 T N+ GD +SD + G IGM P A+LSD+ +FE HG+APDIAGQ KANP + ILS Sbjct: 314 TLNLNGDYVSDALAAEVGGIGMAPGANLSDTH-AIFEATHGTAPDIAGQGKANPSSLILS 372 Query: 342 AAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDI 376 A M+L++ LG +AA+ I A+ + G TGD+ Sbjct: 373 AVMMLEH-LGWGEAAQAIVAAMNATIAAGEVTGDL 406 >1AI3-A nrPDB Length = 416 Score = 88.6 bits (218), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 102/406 (25%), Positives = 172/406 (42%), Gaps = 71/406 (17%) Query: 45 ITLLPGDGIG----PEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVG--VPLPEE 98 I + GDGIG P ++ + +++A E + ++ E+ G + + G V LP E Sbjct: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGE-RKISWMEIYTGEKSTQVYGQDVWLPAE 87 Query: 99 TISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQ 153 T+ +E + G + GG + N + +R L ++ LRP + Sbjct: 88 TLDLIREYRVAIKGPLTTPVGGGIRSLN-----------VALRQELDLYICLRPV----R 132 Query: 154 LVDASTLKREVAEGVDLMVVRELTGGIYFG------------------EPRGIKTNENGE 195 + + E D+++ RE + IY G E G+K E Sbjct: 133 YYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPE 192 Query: 196 EVGFNTEVYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLE----ASILWRKRVT--- 247 G + + R+ R A E A R + V K N+++ A W ++ Sbjct: 193 HCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREE 252 Query: 248 ----------ALASEYP----DVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDE 293 L + P ++ + + D Q++ P ++D I N+ GD +SD Sbjct: 253 FGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDA 312 Query: 294 ASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEE 353 + G IG+ P A++ D LFE HG+AP AGQDK NP + ILSA M+L++ +G Sbjct: 313 LAAQVGGIGIAPGANIGDEC-ALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWT 370 Query: 354 KAAKRIEDAVLVALNNGFRTGDI--YSAGTKLVGCKEMGEEVLKSV 397 +AA I + A+N T D G KL+ C E G+ +++++ Sbjct: 371 EAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 >5M2E-A nrPDB Length = 418 Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 106/407 (26%), Positives = 168/407 (41%), Gaps = 71/407 (17%) Query: 41 KRYTITLLPGDGIG----PEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVG--VP 94 K I + GDGIG P ++ + +++A E + + E+ G A + Sbjct: 27 KNPIIPFIEGDGIGVDISPVMIKVVDAAVEKAYKGER-KIAWMEVYAGEKATQVYDQDTW 85 Query: 95 LPEETISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPAT 149 LP+ET+ A ++ + G + GG + N + +R L ++ RP Sbjct: 86 LPQETLDAVRDYVVSIKGPLTTPVGGGIRSLN-----------VALRQQLDLYVCQRPVR 134 Query: 150 VLPQLVDASTLKREVAEGVDLMVVRELTGGIYFG------------------EPRGIKTN 191 + S +K+ VD+++ RE + IY G E G+K Sbjct: 135 WFEGV--PSPVKK--PGDVDMVIFRENSEDIYAGVEWKAGSPEAEKVIKFLTEEMGVKKI 190 Query: 192 ENGEEVGFNTEVYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLE----ASILWRKRV 246 E G + + R+ R A + A R + V K N+++ A W V Sbjct: 191 RFTENCGIGIKPVSQEGTKRLVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFKDWGYEV 250 Query: 247 T--ALASEYPD---------------VELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDI 289 +E D V + + D Q++ P ++D I T N+ GD Sbjct: 251 ARDEFGAELLDGGPWMQFKNPKTGKNVVVKDVIADAMLQQILLRPAEYDVIATLNLNGDY 310 Query: 290 LSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYG 349 LSD + G IG+ P A+LSDS +FE HG+AP AGQDK NP + ILSA M+L++ Sbjct: 311 LSDALAAEVGGIGIAPGANLSDS-VAMFEATHGTAPKYAGQDKVNPGSLILSAEMMLRH- 368 Query: 350 LGEEKAAKRIEDAVLVALNNGFRTGDI--YSAGTKLVGCKEMGEEVL 394 +G +AA I A+ T D G L+ C E G+ ++ Sbjct: 369 MGWTEAADLIIKGTNGAIAAKTVTYDFERLMDGATLLSCSEFGDAMI 415 >3DMS-A nrPDB Length = 427 Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 104/408 (25%), Positives = 171/408 (41%), Gaps = 73/408 (17%) Query: 45 ITLLPGDGIGPEVVSIAKNVLQQA-----GSLEGVEFNFREMPIGGAALDLVG--VPLPE 97 I + GDG G ++ + V+ A G + + ++ E+ G A + G V LPE Sbjct: 39 IPYIEGDGTGFDITPVMIKVVDAAVEKAYGGKKKI--HWMEIYAGEKATKVYGPDVWLPE 96 Query: 98 ETISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLP 152 ET+ KE + G + GG + N + +R L ++ LRP + Sbjct: 97 ETLQVLKEYVVSIKGPLTTPVGGGIRSLN-----------VALRQELDLYVCLRP---IQ 142 Query: 153 QLVDASTLKREVAEGVDLMVVRELTGGIYFG------------------EPRGIKTNENG 194 + RE E ++++ RE + IY G E G+K Sbjct: 143 YFKGVPSPVRE-PEKTNMVIFRENSEDIYAGIEWAAESEQAKKVIKFLQEEMGVKKIRFP 201 Query: 195 EEVGFNTEVYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLEASI-LWRKRVTALASE 252 + G + + +R+ R A + A R + V K N+++ + +R ALA + Sbjct: 202 QTSGIGIKPVSKEGTERLVRKAIQYAIDNDRKSVTLVHKGNIMKFTEGAFRDAGYALAQK 261 Query: 253 YPDVEL--------------------SHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSD 292 EL D Q++ P ++D I T N+ GD +SD Sbjct: 262 EFGAELIDGGPWMKFKNPKTGNEIVVKDSIADAFLQQILLRPAEYDVIATLNLNGDYISD 321 Query: 293 EASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGE 352 + G IG+ P A+LSDS +FE HG+AP AG+D NP + ILSA M+L++ LG Sbjct: 322 ALAAQVGGIGIAPGANLSDS-VAMFEATHGTAPKYAGKDYVNPGSEILSAEMMLRH-LGW 379 Query: 353 EKAAKRIEDAVLVALNNGFRTGDI--YSAGTKLVGCKEMGEEVLKSVD 398 +AA I A+ ++ T D G V C G+ ++++++ Sbjct: 380 TEAADVIISAMEKSIKQKRVTYDFARLMEGATQVSCSGFGQVLIENME 427 >6C0E-A nrPDB Length = 419 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 94/366 (25%), Positives = 157/366 (42%), Gaps = 69/366 (18%) Query: 45 ITLLPGDGIG----PEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVG--VPLPEE 98 I + GDGIG P ++ + +Q+A + ++ E+ G A + G LP+E Sbjct: 32 IPFIEGDGIGVDVTPPMIRVVDAAVQKAYG-NKRKISWMEVYAGEKATKVYGGDQWLPKE 90 Query: 99 TISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQ 153 T+ A K+ + G + GG + N + IR + ++ LRP + Sbjct: 91 TLDAMKKYVVSIKGPLTTPVGGGIRSLN-----------VAIRQDMDLYVCLRP---IRY 136 Query: 154 LVDASTLKREVAEGVDLMVVRELTGGIYFG------------------EPRGIKTNENGE 195 + RE + D+++ RE + IY G + G+K E Sbjct: 137 FNGVPSPVREPWK-TDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPE 195 Query: 196 EVGFNTEVYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLE----ASILWRKRV---T 247 G + + R+ + A + A R + V K N+++ A W +V + Sbjct: 196 HCGIGVKPVSREGTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDS 255 Query: 248 ALASEY---PDVELSH-----------MYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDE 293 A EY P +E + + D Q++ P+ + I T N+ GD +SD Sbjct: 256 FGAKEYQGGPWMEFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATLNLNGDYISDA 315 Query: 294 ASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEE 353 + G IG+ P A++SD +FE HG+AP AGQ+K NP + ILSA M+L++ +G Sbjct: 316 LAAQVGGIGIAPGANISDQ-MAVFEATHGTAPKYAGQNKVNPGSIILSAEMMLRH-MGWY 373 Query: 354 KAAKRI 359 +AA I Sbjct: 374 EAADLI 379 >4AOY-A nrPDB Length = 402 Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 17/163 (10%) Query: 252 EYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSD 311 E +++ + +D+A +++R N GD++SD + GS+ M+ S +S Sbjct: 238 EAKNLQYFYTLIDDAVARIIRSEGGM-VWACKNYDGDVMSDMVASAFGSLAMMTSVLVSP 296 Query: 312 SGPGLFEPIHGSA-----PDIAGQDKA-NPLATILSAAMLLKY-----GLGE-EKAAKRI 359 G FE HG+ + G++ + N +ATI + LK G+ E A ++ Sbjct: 297 DGKYEFEAAHGTVTRHYYKHLKGEETSTNSMATIFAWTGALKKRGELDGIKELVDFATKL 356 Query: 360 EDAVLVALNNGFRTGDIYSAG----TKLVGCKEMGEEVLKSVD 398 E A + + NG T D+ S K+V ++ +E+ K+ + Sbjct: 357 EQASVQTIENGVMTKDLASLSEVPEKKIVNTEDFLKEIRKTFE 399 >1ZOR-A nrPDB Length = 399 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 43/161 (26%), Positives = 74/161 (45%), Gaps = 19/161 (11%) Query: 256 VELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPG 315 V +M +D+AA Q++R N GDI+SD + GS+G++ S +S G Sbjct: 239 VNYRYMLIDDAAAQILRSEGGM-LWACMNYEGDIMSDMIASGFGSLGLMTSVLVSPDGVY 297 Query: 316 LFEPIHGSAPD-----IAGQDKA-NPLATILSAAMLLKYGLGE-------EKAAKRIEDA 362 FE HG+ + G+ + NP A+I + ++ GE + A ++E A Sbjct: 298 EFEAAHGTVRRHYYRYLKGEKTSTNPTASIFAWTGAIR-KRGELDGTPEVCEFADKLEKA 356 Query: 363 VLVALNNGFRTGDIYSAG----TKLVGCKEMGEEVLKSVDS 399 V+ + +G T D+ K V +E +EV K+++ Sbjct: 357 VINTIESGVITKDLQPFTEPPIDKYVTLEEFIDEVKKNLEK 397 >2UXQ-A nrPDB Length = 402 Score = 31.2 bits (69), Expect = 0.84, Method: Compositional matrix adjust. Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 14/108 (12%) Query: 282 TNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQD------KANP 335 N GD++SD + GS+ M+ S +S G +E HG+ Q NP Sbjct: 266 CKNYDGDVMSDMVASAFGSLAMMSSVLVSPYGYFEYEAAHGTVQRHYYQHLKGERTSTNP 325 Query: 336 LATILSAAMLLKYGLGEEKA-------AKRIEDAVLVALNNGFRTGDI 376 +A I + L+ GE +E + + +G+ TGD+ Sbjct: 326 VALIYAWTGALR-KRGELDGTPDLCAFCDSLEAITIECIESGYMTGDL 372 >6BL1-B nrPDB Length = 425 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 34/138 (24%), Positives = 57/138 (41%), Gaps = 14/138 (10%) Query: 252 EYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSD 311 E + H +D+ Q ++ F N GD+ SD + GS+GM+ S + Sbjct: 240 EAQKIWYEHRLIDDMVAQAMKSEGGF-IWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCP 298 Query: 312 SGPGL-FEPIHGSAPDI-----AGQDKA-NPLATILSAAMLLKY--GLGEEKA----AKR 358 G + E HG+ GQ+ + NP+A+I + L + L K A Sbjct: 299 DGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANA 358 Query: 359 IEDAVLVALNNGFRTGDI 376 +E+ + + GF T D+ Sbjct: 359 LEEVSIETIEAGFMTKDL 376 >4GYR-A nrPDB Length = 621 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 18/49 (36%), Positives = 23/49 (46%) Query: 121 NNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVD 169 NN ++P KGLL + +L TV V TL R +AEG D Sbjct: 209 NNLVGVKPTKGLLSTSGVVPACRSLDCVTVFAASVAEGTLIRRIAEGYD 257 >1PC2-A nrPDB Length = 152 Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust. Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 3/46 (6%) Query: 92 GVPLPEETI---SAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQ 134 G+ L EE + S ++ D V A+G Y+ EK L+ +GLLQ Sbjct: 54 GIVLLEELLPKGSKEEQRDYVFYLAVGNYRLKEYEKALKYVRGLLQ 99 >4HCX-A nrPDB Length = 409 Score = 28.5 bits (62), Expect = 6.1, Method: Compositional matrix adjust. Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 13/106 (12%) Query: 284 NIFGDILSDEASMITGSIGMLPSASLSDSGPGL-FEPIHGSAPDIAGQDKA------NPL 336 N GD+ SD + GS+G++ S ++ G + E HG+ Q +A NP+ Sbjct: 274 NYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPI 333 Query: 337 ATILSAAMLLKY-----GLGEE-KAAKRIEDAVLVALNNGFRTGDI 376 A+I + L++ G E A ++E V+ + +G T D+ Sbjct: 334 ASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDL 379 >2PWJ-A nrPDB Length = 171 Score = 28.1 bits (61), Expect = 6.6, Method: Compositional matrix adjust. Identities = 38/159 (23%), Positives = 68/159 (42%), Gaps = 22/159 (13%) Query: 54 GPEVVSIAKNV-LQQAGSL-EGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLL 111 G +++S A NV LQ+A + EGVE F P+ D+ K+ V+ Sbjct: 6 GTDILSAASNVSLQKARTWDEGVESKFSTTPVN----DIF------------KDKKVVIF 49 Query: 112 GAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLM 171 G G Y + KH+ P K + A V + + A P V+A K + + ++ Sbjct: 50 GLPGAYTGVCSSKHVPPYKHNIDKFKAKGVDSVICVAINDPYTVNAWAEKIQAKDAIEFY 109 Query: 172 VVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEID 210 + G F + + T+ + +G +E ++A+ +D Sbjct: 110 --GDFDGS--FHKSLELTTDLSAGLLGIRSERWSAYVVD 144 >2RI0-A nrPDB Length = 234 Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 20/32 (62%) Query: 324 APDIAGQDKANPLATILSAAMLLKYGLGEEKA 355 A D+ Q + LA+I+SA M+L GEEKA Sbjct: 165 AEDVPKQAISMGLASIMSAKMILLMAFGEEKA 196 >5XJV-A nrPDB Length = 185 Score = 27.7 bits (60), Expect = 8.3, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 3/39 (7%) Query: 323 SAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIED 361 S P++ G+DKA P +IL LL+ G + +A R+++ Sbjct: 5 SLPELGGEDKATPAPSILELEELLRAG---KSSASRVDE 40 >2QFY-A nrPDB Length = 427 Score = 27.7 bits (60), Expect = 8.9, Method: Compositional matrix adjust. Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Query: 256 VELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPG 315 + H +D+ Q+++ F + N GD+ SD + GS+G++ S ++ G Sbjct: 260 IHYEHRLIDDMVAQMIKSKGGF-IMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKT 318 Query: 316 L-FEPIHGS 323 E HG+ Sbjct: 319 FESEAAHGT 327 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5J32-A nrPDB 499 e-141 3U1H-A nrPDB 488 e-138 3VMK-A nrPDB 464 e-131 3VML-A nrPDB 464 e-131 1CM7-A nrPDB 461 e-130 3VMJ-A nrPDB 460 e-130 1CNZ-A nrPDB 459 e-130 1V5B-A nrPDB 453 e-128 1VLC-A nrPDB 451 e-127 1A05-A nrPDB 439 e-123 4IWH-A nrPDB 437 e-123 1XAD-A nrPDB 425 e-119 3UDO-A nrPDB 420 e-118 1IDM-A nrPDB 413 e-116 2IV0-A nrPDB 377 e-105 1AI3-A nrPDB 372 e-103 5M2E-A nrPDB 365 e-101 1HQS-A nrPDB 363 e-101 2E5M-A nrPDB 362 e-100 5YVT-A nrPDB 360 e-100 3DMS-A nrPDB 358 2e-99 3ASJ-A nrPDB 358 3e-99 6C0E-A nrPDB 355 1e-98 3FMX-X nrPDB 355 2e-98 3TY3-A nrPDB 344 4e-95 4Y1P-A nrPDB 344 4e-95 1XGV-A nrPDB 343 6e-95 2D1C-A nrPDB 343 8e-95 1WPW-A nrPDB 340 9e-94 2D4V-A nrPDB 337 5e-93 3BLV-B nrPDB 337 6e-93 5GRH-B nrPDB 331 3e-91 3BLX-A nrPDB 324 4e-89 2G4O-A nrPDB 315 2e-86 5HN5-A nrPDB 309 1e-84 4AOY-A nrPDB 150 1e-36 Sequences not found previously or not previously below threshold: 1ZOR-A nrPDB 138 6e-33 2UXQ-A nrPDB 124 7e-29 6BL1-B nrPDB 116 2e-26 5I96-A nrPDB 115 4e-26 4HCX-A nrPDB 114 8e-26 3US8-A nrPDB 112 4e-25 2QFY-A nrPDB 108 3e-24 6DUE-A nrPDB 36 0.026 4JQP-A nrPDB 33 0.25 3ABT-A nrPDB 32 0.39 1EAR-A nrPDB 32 0.42 5L3D-A nrPDB 32 0.54 1IY9-A nrPDB 30 1.8 3R4T-A nrPDB 30 2.0 5ZQM-A nrPDB 30 2.1 3RHD-A nrPDB 30 2.1 1VGT-A nrPDB 30 2.8 6AJJ-A nrPDB 29 3.7 2HI1-A nrPDB 29 4.5 5ZBN-A nrPDB 28 5.8 1AL8-A nrPDB 28 5.8 2CDH-0 nrPDB 28 8.3 3O3U-N nrPDB 28 8.7 >5J32-A nrPDB Length = 403 Score = 499 bits (1284), Expect = e-141, Method: Composition-based stats. Identities = 367/367 (100%), Positives = 367/367 (100%) Query: 39 GKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEE 98 GKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEE Sbjct: 37 GKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEE 96 Query: 99 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS 158 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS Sbjct: 97 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS 156 Query: 159 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 218 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE Sbjct: 157 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 216 Query: 219 TARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD 278 TARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD Sbjct: 217 TARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD 276 Query: 279 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT 338 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT Sbjct: 277 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT 336 Query: 339 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD 398 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD Sbjct: 337 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD 396 Query: 399 SQVPASV 405 SQVPASV Sbjct: 397 SQVPASV 403 >3U1H-A nrPDB Length = 390 Score = 488 bits (1255), Expect = e-138, Method: Composition-based stats. Identities = 220/366 (60%), Positives = 259/366 (70%), Gaps = 2/366 (0%) Query: 39 GKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEE 98 G + I +LPGDGIGPEV+ A VL+ G EF F IGGAA+D G PLPEE Sbjct: 20 GAMKKKIAVLPGDGIGPEVMEAAIEVLKAVAERFGHEFEFEYGLIGGAAIDEAGTPLPEE 79 Query: 99 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS 158 T+ + SDA+LLGA+GG KWD N LRPEKGLL IR L +FANLRP V L DAS Sbjct: 80 TLDVCRGSDAILLGAVGGPKWDQNPSELRPEKGLLGIRKGLDLFANLRPVKVYDSLADAS 139 Query: 159 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 218 LK+EV EGVDL++VRELTGG+YFGEP + E GEE +T +Y EI+RI R AFE Sbjct: 140 PLKKEVIEGVDLVIVRELTGGLYFGEPS--ERYEEGEEAAVDTLLYTREEIERIIRKAFE 197 Query: 219 TARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD 278 A R+ K+ SVDKANVLE+S LWR+ +A EYPDVEL HM VDNAAMQL+R+P+QFD Sbjct: 198 LALTRKKKVTSVDKANVLESSRLWREVAEEVAKEYPDVELEHMLVDNAAMQLIRNPRQFD 257 Query: 279 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT 338 IVT N+FGDILSDEASMITGS+GMLPSASLS G GL+EP+HGSAPDIAG+ ANPLAT Sbjct: 258 VIVTENMFGDILSDEASMITGSLGMLPSASLSTDGLGLYEPVHGSAPDIAGKGIANPLAT 317 Query: 339 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD 398 ILSAAM+L+Y G E+ AK IE AV L G+RT DI G K V EM +EV +V Sbjct: 318 ILSAAMMLRYSFGLEEEAKAIEKAVEKVLAEGYRTADIAKPGGKYVSTTEMTDEVKAAVV 377 Query: 399 SQVPAS 404 ++ S Sbjct: 378 DELATS 383 >3VMK-A nrPDB Length = 375 Score = 464 bits (1195), Expect = e-131, Method: Composition-based stats. Identities = 170/359 (47%), Positives = 247/359 (68%), Gaps = 5/359 (1%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 Y I +L GDGIGPEV++ A+ VL + + E +GGAA+D G PLPE T+ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLAAVEKRFDLSIEYSEYDVGGAAIDNHGCPLPEATLKG 73 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLVDASTLK 161 + +DAVL G++GG KW++ + +PE+G LL +R ++F N+RPA + P L S L+ Sbjct: 74 CEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPLR 133 Query: 162 REVAE-GVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA 220 +++E G D++ VRELTGGIYFG+P+G + E E F+T Y+ EI RIA++AFE+A Sbjct: 134 SDISEKGFDILCVRELTGGIYFGKPKG-RQGEGENEEAFDTMRYSRKEIRRIAKIAFESA 192 Query: 221 RKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 + RR K+ SVDKANVL S+LWR+ V +A +YPDVEL H+Y+DNA MQL+R P +FD + Sbjct: 193 QGRRKKVTSVDKANVLACSVLWREVVEEVAKDYPDVELEHIYIDNATMQLLRRPNEFDVM 252 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 + +N+FGDI+SDE +M+TGS+G+L S S++ G G++EP GSAPDIAGQ ANP+A IL Sbjct: 253 LCSNLFGDIVSDEIAMLTGSMGLLASISMNSQGFGMYEPAGGSAPDIAGQGIANPVAQIL 312 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAG--TKLVGCKEMGEEVLKSV 397 SAA+LL++ L E AA IE AV AL++G+ T ++ A ++ +MG+ + +++ Sbjct: 313 SAALLLRHSLKLEDAALAIEAAVSKALSDGYLTCELLPASERSQAKSTSQMGDYIAQAI 371 >3VML-A nrPDB Length = 375 Score = 464 bits (1193), Expect = e-131, Method: Composition-based stats. Identities = 175/363 (48%), Positives = 251/363 (69%), Gaps = 5/363 (1%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 Y I +L GDGIGPEV++ A+ VL+ + G+ + E +GG A+D G PLPE T+ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLVDASTLK 161 + +DAVL G++GG KW++ + +PE+G LL +R ++F N+RPA + P L S L+ Sbjct: 74 CEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPLR 133 Query: 162 REVAE-GVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA 220 +++E G D++ VRELTGGIYFG+P+G + E E F+T Y+ EI RIA++AFE+A Sbjct: 134 SDISEKGFDILCVRELTGGIYFGKPKG-RQGEGENEEAFDTMRYSRKEIRRIAKIAFESA 192 Query: 221 RKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 + RR K+ SVDKANVL S+LWR+ V +A +YPDVEL H+Y+DNA MQL+R P +FD + Sbjct: 193 QGRRKKVTSVDKANVLACSVLWREVVEEVAKDYPDVELEHIYIDNATMQLLRRPNEFDVM 252 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 + +N+FGDI+SDE +M+TGS+G+L S S++ G G++EP GSAPDIAGQ ANP+A IL Sbjct: 253 LCSNLFGDIVSDEIAMLTGSMGLLASISMNSQGFGMYEPAGGSAPDIAGQGIANPVAQIL 312 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGT--KLVGCKEMGEEVLKSVD 398 SAA+LL++ L E AA IE AV ALN+G+ TG++ S+ K +MG+ + +V Sbjct: 313 SAALLLRHSLKLEDAALAIEAAVSKALNSGYLTGELLSSDQRHKAKTTVQMGDFIADAVK 372 Query: 399 SQV 401 + V Sbjct: 373 AGV 375 >1CM7-A nrPDB Length = 363 Score = 461 bits (1186), Expect = e-130, Method: Composition-based stats. Identities = 187/360 (51%), Positives = 251/360 (69%), Gaps = 4/360 (1%) Query: 40 KKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEET 99 K Y I +LPGDGIGPEV++ A VL + + +GGAA+D G PLP T Sbjct: 2 SKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPAT 61 Query: 100 ISAAKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLVDAS 158 + +++DAVL G++GG KW++ +PE+G LL +R K+F+NLRPA + L Sbjct: 62 VEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFC 121 Query: 159 TLKREVA-EGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAF 217 L+ ++A G D++ VRELTGGIYFG+P+G + E F+TEVY EI+RIAR+AF Sbjct: 122 PLRADIAANGFDILCVRELTGGIYFGQPKG-REGSGQYEKAFDTEVYHRFEIERIARIAF 180 Query: 218 ETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQF 277 E+ARKRR K+ S+DKANVL++SILWR+ V +A+EYPDVEL+HMY+DNA MQL++DP QF Sbjct: 181 ESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQF 240 Query: 278 DTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLA 337 D ++ +N+FGDILSDE +MITGS+GMLPSASL++ G GL+EP GSAPDIAG++ ANP+A Sbjct: 241 DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIA 300 Query: 338 TILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 397 ILS A+LL+Y L + AA IE A+ AL G RTGD+ G V EMG+ + + V Sbjct: 301 QILSLALLLRYSLDADDAACAIERAINRALEEGIRTGDLAR-GAAAVSTDEMGDIIARYV 359 >3VMJ-A nrPDB Length = 375 Score = 460 bits (1183), Expect = e-130, Method: Composition-based stats. Identities = 177/363 (48%), Positives = 251/363 (69%), Gaps = 5/363 (1%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 Y I +L GDGIGPEV++ A+ VL+ + G+ + E +GG A+D G PLPE T+ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLVDASTLK 161 + +DA+L G++GG KW+ + +PE+G LL +R ++F NLRPA + L S L+ Sbjct: 74 CEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHMSPLR 133 Query: 162 REV-AEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA 220 ++ A G D++ VRELTGGIYFG+P+G + E E F+T Y+ EI RIAR+AFE A Sbjct: 134 SDISARGFDVLCVRELTGGIYFGKPKG-RQGEGESEEAFDTMRYSRREISRIARIAFEAA 192 Query: 221 RKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 R RR K+ SVDKANVL S+LWR+ V +A ++PDVEL H+Y+DNA MQL+R P +FD + Sbjct: 193 RGRRKKVTSVDKANVLACSVLWRQVVEEVAVDFPDVELEHIYIDNATMQLLRRPDEFDVM 252 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 + +N+FGDILSDE +M+TGS+G+L SAS++ +G GLFEP GSAPDIAG+ ANP+A IL Sbjct: 253 LCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGLFEPAGGSAPDIAGKGIANPIAQIL 312 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGT--KLVGCKEMGEEVLKSVD 398 SAA++L++ L +E+AA IE AV ALN+G+ TG++ S+ K +MG+ + +V Sbjct: 313 SAALMLRHSLKQEEAASAIERAVTKALNSGYLTGELLSSDQRHKAKTTVQMGDFIADAVK 372 Query: 399 SQV 401 + V Sbjct: 373 AGV 375 >1CNZ-A nrPDB Length = 363 Score = 459 bits (1182), Expect = e-130, Method: Composition-based stats. Identities = 185/360 (51%), Positives = 248/360 (68%), Gaps = 4/360 (1%) Query: 40 KKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEET 99 K Y I +LPGDGIGPEV++ A V+ S + +GG A+D G PLP+ T Sbjct: 2 SKNYHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKAT 61 Query: 100 ISAAKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLVDAS 158 + +++DA+L G++GG KW+N +PE+G LL +R K+F+NLRPA + L Sbjct: 62 VEGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFC 121 Query: 159 TLKREVA-EGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAF 217 L+ ++A G D++ VRELTGGIYFG+P+G + E F+TEVY EI+RIAR+AF Sbjct: 122 PLRADIAANGFDILCVRELTGGIYFGQPKG-REGSGQYEKAFDTEVYHRFEIERIARIAF 180 Query: 218 ETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQF 277 E+ARKRR K+ S+DKANVL++SILWR+ V +A YPDVEL+HMY+DNA MQL++DP QF Sbjct: 181 ESARKRRRKVTSIDKANVLQSSILWREIVNDVAKTYPDVELAHMYIDNATMQLIKDPSQF 240 Query: 278 DTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLA 337 D ++ +N+FGDILSDE +MITGS+GMLPSASL++ G GL+EP GSAPDIAG++ ANP+A Sbjct: 241 DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIA 300 Query: 338 TILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 397 ILS A+LL+Y L AA IE A+ AL G RTGD+ G V EMG+ + + V Sbjct: 301 QILSLALLLRYSLDANDAATAIEQAINRALEEGVRTGDLAR-GAAAVSTDEMGDIIARYV 359 >1V5B-A nrPDB Length = 366 Score = 453 bits (1166), Expect = e-128, Method: Composition-based stats. Identities = 193/362 (53%), Positives = 247/362 (68%), Gaps = 2/362 (0%) Query: 41 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETI 100 + + +LPGDGIGPEV+ A VL+ +G E F IGGAA+D G PLPEET+ Sbjct: 1 MKMKLAVLPGDGIGPEVMDAAIRVLKTVLDNDGHEAVFENALIGGAAIDEAGTPLPEETL 60 Query: 101 SAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTL 160 + SDA+LLGA+GG KWD+N LRPEKGLL +R + +FANLRP L++AS L Sbjct: 61 DICRRSDAILLGAVGGPKWDHNPASLRPEKGLLGLRKEMGLFANLRPVKAYATLLNASPL 120 Query: 161 KREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA 220 KRE E VDL++VRELTGG+YFG P + GE +T Y EI+RI AF+ A Sbjct: 121 KRERVENVDLVIVRELTGGLYFGRPS--ERRGPGENEVVDTLAYTREEIERIIEKAFQLA 178 Query: 221 RKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 + RR KL SVDKANVLE+S +WR+ A +YPDVELSHM VD+ AMQL+ +P QFD I Sbjct: 179 QIRRKKLASVDKANVLESSRMWREIAEETAKKYPDVELSHMLVDSTAMQLIANPGQFDVI 238 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 VT N+FGDILSD AS+ITGS+GMLPSASL G++EP+HGSAPDIAGQ KANPL T+L Sbjct: 239 VTENMFGDILSDLASVITGSLGMLPSASLRSDRFGMYEPVHGSAPDIAGQGKANPLGTVL 298 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDSQ 400 SAA++L+Y G EK A IE AV L +G+ TGD+ A K+V E+ + +++ +++ Sbjct: 299 SAALMLRYSFGLEKEAAAIEKAVDDVLQDGYCTGDLQVANGKVVSTIELTDRLIEKLNNS 358 Query: 401 VP 402 Sbjct: 359 AA 360 >1VLC-A nrPDB Length = 366 Score = 451 bits (1160), Expect = e-127, Method: Composition-based stats. Identities = 181/358 (50%), Positives = 238/358 (66%), Gaps = 9/358 (2%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 I +LPGDGIGPEVV A VL+ G F IGG A+D G PLPEET Sbjct: 13 MKIAVLPGDGIGPEVVREALKVLEVVEKKTGKTFEKVFGHIGGDAIDRFGEPLPEETKKI 72 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPE-KGLLQIRAALKVFANLRPATVLPQLVDASTLK 161 E+DA+ LG++GG KWD+ RPE GLL +R L ++AN+RP V LV S LK Sbjct: 73 CLEADAIFLGSVGGPKWDDLPPEKRPEIGGLLALRKMLNLYANIRPIKVYRSLVHVSPLK 132 Query: 162 RE-VAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA 220 + + GVDL+ VREL+ G+Y+G+PRG+ EE GF+T +Y ++RIAR AFE A Sbjct: 133 EKVIGSGVDLVTVRELSYGVYYGQPRGLD-----EEKGFDTMIYDRKTVERIARTAFEIA 187 Query: 221 RKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 + RR K+ SVDKANVL +S+LWRK V +A EYPDVEL+H+YVDNAAMQL+ P QFD I Sbjct: 188 KNRRKKVTSVDKANVLYSSMLWRKVVNEVAREYPDVELTHIYVDNAAMQLILKPSQFDVI 247 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 +T N+FGDILSDE++ + GS+G+LPSAS D L+EP GSAPDIAG++ ANP+A IL Sbjct: 248 LTTNMFGDILSDESAALPGSLGLLPSASFGDKN--LYEPAGGSAPDIAGKNIANPIAQIL 305 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVD 398 S AM+L++ G + A++IE AV + + G+RT DI K V +MG+ + K ++ Sbjct: 306 SLAMMLEHSFGMVEEARKIERAVELVIEEGYRTRDIAEDPEKAVSTSQMGDLICKKLE 363 >1A05-A nrPDB Length = 358 Score = 439 bits (1128), Expect = e-123, Method: Composition-based stats. Identities = 200/358 (55%), Positives = 255/358 (71%), Gaps = 2/358 (0%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 I + GDGIGPE+V+ A+ VL + E +GGAALD PLP ++ Sbjct: 2 KKIAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDPLPAASLQL 61 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKR 162 A +DAV+LGA+GG +WD RPE+GLL++R L ++ANLRPA + PQL+DAS L+ Sbjct: 62 AMAADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLRP 121 Query: 163 EVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARK 222 E+ VD++VVRELTG IYFG+PRG++ +G+ GFNT VY EI RIA VAF A+ Sbjct: 122 ELVRDVDILVVRELTGDIYFGQPRGLEVI-DGKRRGFNTMVYDEDEIRRIAHVAFRAAQG 180 Query: 223 RRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVT 282 RR +LCSVDKANVLE + LWR+ VT +A +YPDV LSHMYVDNAAMQL+R P QFD ++T Sbjct: 181 RRKQLCSVDKANVLETTRLWREVVTEVARDYPDVRLSHMYVDNAAMQLIRAPAQFDVLLT 240 Query: 283 NNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSA 342 N+FGDILSDEAS +TGSIGMLPSASL G ++EPIHGSAPDIAGQDKANPLATILS Sbjct: 241 GNMFGDILSDEASQLTGSIGMLPSASLG-EGRAMYEPIHGSAPDIAGQDKANPLATILSV 299 Query: 343 AMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDSQ 400 AM+L++ L E A+R+E AV L+ G RT DI + GT ++G K MG V+ +++ + Sbjct: 300 AMMLRHSLNAEPWAQRVEAAVQRVLDQGLRTADIAAPGTPVIGTKAMGAAVVNALNLK 357 >4IWH-A nrPDB Length = 363 Score = 437 bits (1125), Expect = e-123, Method: Composition-based stats. Identities = 201/367 (54%), Positives = 255/367 (69%), Gaps = 8/367 (2%) Query: 35 VASPGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVP 94 +A I +LPGDGIGPE+V+ A VL F P+GGA + G P Sbjct: 1 MAHHHHHHMKIAVLPGDGIGPEIVNEAVKVLNALDEK----FELEHAPVGGAGYEASGHP 56 Query: 95 LPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQL 154 LP+ T++ AKE+DA+L GA+G +K+D+ E+ LRPE+ +L +R L++FAN RPA PQL Sbjct: 57 LPDATLALAKEADAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQL 116 Query: 155 VDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENG----EEVGFNTEVYAAHEID 210 VDAS LK E+ G+D+++VREL G IYFG+PRG++ +G E GF+T Y+ E+ Sbjct: 117 VDASPLKPELVAGLDILIVRELNGDIYFGQPRGVRAAPDGPFAGEREGFDTMRYSEPEVR 176 Query: 211 RIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQL 270 RIA VAF+ A+KR KL SVDK+NVLE S WR + ++ EY DVELSHMYVDNAAMQL Sbjct: 177 RIAHVAFQAAQKRAKKLLSVDKSNVLETSQFWRDVMIDVSKEYADVELSHMYVDNAAMQL 236 Query: 271 VRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQ 330 + PKQFD IVT N+FGDILSDEASM+TGSIGMLPSASL + GL+EP HGSAPDIAG+ Sbjct: 237 AKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSASLDKNNKGLYEPSHGSAPDIAGK 296 Query: 331 DKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMG 390 ANPLATILSAAMLL+Y L + A RIE AV L G+RTGDI + G + VG MG Sbjct: 297 GIANPLATILSAAMLLRYSLNRAEQADRIERAVKTVLEQGYRTGDIATPGCRQVGTAAMG 356 Query: 391 EEVLKSV 397 + V+ ++ Sbjct: 357 DAVVAAL 363 >1XAD-A nrPDB Length = 345 Score = 425 bits (1093), Expect = e-119, Method: Composition-based stats. Identities = 186/355 (52%), Positives = 232/355 (65%), Gaps = 11/355 (3%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 + +LPGDGIGPEV A VL+ EG+ + P GGAA+D G P PE T Sbjct: 1 MKVAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKG 60 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKR 162 +E++AVLLG++GG KWD N + LRPEKGLL IR L +FANLRP V L DAS LK+ Sbjct: 61 VEEAEAVLLGSVGGPKWDQNPRELRPEKGLLSIRKQLDLFANLRPVKVFESLSDASPLKK 120 Query: 163 EVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARK 222 E + VD ++VRELTGGIYFGEPRG+ E +NTE Y+ E++R+ARVAFE ARK Sbjct: 121 EYIDNVDFVIVRELTGGIYFGEPRGMSEAE-----AWNTERYSKPEVERVARVAFEAARK 175 Query: 223 RRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVT 282 RR + SVDKANVLE WRK V + YPDV L H YVD AM LVR P +FD +VT Sbjct: 176 RRKHVVSVDKANVLEVGEFWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVT 235 Query: 283 NNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSA 342 NIFGDILSD AS++ GS+G+LPSASL G +FEP+HGSAPDIAG+ ANP A ILSA Sbjct: 236 GNIFGDILSDLASVLPGSLGLLPSASLGR-GTPVFEPVHGSAPDIAGKGIANPTAAILSA 294 Query: 343 AMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 397 AM+L++ G + A+++EDAV AL D+ + G + VL+ + Sbjct: 295 AMMLEHAFGLVELARKVEDAVAKALLETP-PPDLGGSA----GTEAFTATVLRHL 344 >3UDO-A nrPDB Length = 361 Score = 420 bits (1080), Expect = e-118, Method: Composition-based stats. Identities = 174/364 (47%), Positives = 239/364 (65%), Gaps = 10/364 (2%) Query: 37 SPGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLP 96 S K Y + +L GDGIGP V+ A +L F E IGGA++D GV L Sbjct: 1 SNAMKTYKVAVLAGDGIGPLVMKEALKILTFIAQKYNFSFELNEAKIGGASIDAYGVALS 60 Query: 97 EETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKG-LLQIRAALKVFANLRPATVLPQLV 155 +ET+ ++SDA+L G++GG KWDN RPE+ LL +R +FANLRP + L Sbjct: 61 DETLKLCEQSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLT 120 Query: 156 DASTLKREVA-EGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIAR 214 AS LK E+ +GVD++ VRELTGGIYFG + G+E ++TE+Y EI+RIAR Sbjct: 121 HASPLKNEIIQKGVDILCVRELTGGIYFG------KQDLGKESAYDTEIYTKKEIERIAR 174 Query: 215 VAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDP 274 +AFE+AR R+ K+ +DKANVL +SILWR+ V +A +Y D+ L +MYVDNAAMQ+V++P Sbjct: 175 IAFESARIRKKKVHLIDKANVLASSILWREVVANVAKDYQDINLEYMYVDNAAMQIVKNP 234 Query: 275 KQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKAN 334 FD ++ +N+FGDILSDE + I GS+G+L SASL+D G GL+EP GSAPDIA + AN Sbjct: 235 SIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNIAN 294 Query: 335 PLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVL 394 P+A ILSAA++LKY EE+AA+ IE+A+ +AL G T D+ + EMG+ +L Sbjct: 295 PIAQILSAALMLKYSFKEEQAAQDIENAISLALAQGKMTKDL--NAKSYLNTDEMGDCIL 352 Query: 395 KSVD 398 + + Sbjct: 353 EILK 356 >1IDM-A nrPDB Length = 343 Score = 413 bits (1062), Expect = e-116, Method: Composition-based stats. Identities = 182/355 (51%), Positives = 231/355 (65%), Gaps = 13/355 (3%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 + +LPGDGIGPEV A VL+ EG+ + P GGAA+D G P PE T Sbjct: 1 MKVAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKG 60 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKR 162 +E++AVLLG++GG KW +RPE+GLL +R + +FANLRPA V P L S LK Sbjct: 61 VEEAEAVLLGSVGGPKW--GTGSVRPEQGLLSLRKSQDLFANLRPAKVFPGLERLSPLKE 118 Query: 163 EVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARK 222 E+A GVD+++VRELTGGIYFGEPRG+ E +NTE Y+ E++R+ARVAFE ARK Sbjct: 119 EIARGVDVLIVRELTGGIYFGEPRGMSEAE-----AWNTERYSKPEVERVARVAFEAARK 173 Query: 223 RRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVT 282 RR + SVDKANVLE WRK V + YPDV L H YVD AM LVR P +FD +VT Sbjct: 174 RRKHVVSVDKANVLEVGEFWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVT 233 Query: 283 NNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSA 342 NIFGDILSD AS++ GS+G+LPSASL G +FEP+HGSAPDIAG+ ANP A ILSA Sbjct: 234 GNIFGDILSDLASVLPGSLGLLPSASLGR-GTPVFEPVHGSAPDIAGKGIANPTAAILSA 292 Query: 343 AMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 397 AM+L++ G + A+++EDAV AL D+ + G + VL+ + Sbjct: 293 AMMLEHAFGLVELARKVEDAVAKALLETP-PPDLGGSA----GTEAFTATVLRHL 342 >2IV0-A nrPDB Length = 412 Score = 377 bits (967), Expect = e-105, Method: Composition-based stats. Identities = 118/402 (29%), Positives = 187/402 (46%), Gaps = 61/402 (15%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETIS 101 I GDGIG +VV A VL A G E + ++ G A L G LP++T++ Sbjct: 27 NPIIPYFEGDGIGKDVVPAAIRVLDAAADKIGKEVVWFQVYAGEDAYKLYGNYLPDDTLN 86 Query: 102 AAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVD 156 A KE L G + GGY+ N + IR L ++AN+RP L + Sbjct: 87 AIKEFRVALKGPLTTPVGGGYRSLN-----------VTIRQVLDLYANVRPVYYLKGV-- 133 Query: 157 ASTLKREVAEGVDLMVVRELTGGIYFG--EPRGIKT---------NENG----EEVGFNT 201 + E V+ ++ RE T +Y G PRG + NE G E+ G Sbjct: 134 --PSPIKHPEKVNFVIFRENTEDVYAGIEWPRGSEEALKLIRFLKNEFGVTIREDSGIGI 191 Query: 202 EVYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLEAS-ILWRKRVTALAS----EY-- 253 + + R+ R+A A R + V K N+++ + +R +A EY Sbjct: 192 KPISEFATKRLVRMAIRYAIENNRKSVTLVHKGNIMKYTEGAFRDWGYEVAKQEFGEYCI 251 Query: 254 ---------------PDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMIT 298 + + DN Q++ ++D I N+ GD LSD A+ + Sbjct: 252 TEDELWDKYGGKQPEGKIVVKDRIADNMFQQILTRTDEYDVIALPNLNGDYLSDAAAALI 311 Query: 299 GSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKR 358 G +G+ P +++ D G G+FEP+HGSAP AGQ+K NP A IL+ A++ +Y +G + A++ Sbjct: 312 GGLGIAPGSNIGD-GIGVFEPVHGSAPKYAGQNKVNPTAEILTGALMFEY-IGWKDASEM 369 Query: 359 IEDAVLVALNNGFRTGDIYS-AGTKLVGCKEMGEEVLKSVDS 399 I+ AV + +++G T DI+ G VG +E E V++++ S Sbjct: 370 IKKAVEMTISSGIVTYDIHRHMGGTKVGTREFAEAVVENLQS 411 >1AI3-A nrPDB Length = 416 Score = 372 bits (956), Expect = e-103, Method: Composition-based stats. Identities = 100/408 (24%), Positives = 165/408 (40%), Gaps = 69/408 (16%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLE---GVEFNFREMPIGGAALDLVGV--PLP 96 I + GDGIG +V V+ A + ++ E+ G + + G LP Sbjct: 26 NPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLP 85 Query: 97 EETISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVL 151 ET+ +E + G + GG + N + +R L ++ LRP Sbjct: 86 AETLDLIREYRVAIKGPLTTPVGGGIRSLN-----------VALRQELDLYICLRPVRYY 134 Query: 152 PQLVDASTLKREVAEGVDLMVVRELTGGIYFG------------------EPRGIKTNEN 193 + + E D+++ RE + IY G E G+K Sbjct: 135 QG----TPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRF 190 Query: 194 GEEVGFNTEVYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLEAS-ILWRKRVTALAS 251 E G + + R+ R A E A R + V K N+++ + ++ LA Sbjct: 191 PEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAR 250 Query: 252 EY--------------------PDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILS 291 E ++ + + D Q++ P ++D I N+ GD +S Sbjct: 251 EEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYIS 310 Query: 292 DEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLG 351 D + G IG+ P A++ D LFE HG+AP AGQDK NP + ILSA M+L++ +G Sbjct: 311 DALAAQVGGIGIAPGANIGDEC-ALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MG 368 Query: 352 EEKAAKRIEDAVLVALNNGFRTGDI--YSAGTKLVGCKEMGEEVLKSV 397 +AA I + A+N T D G KL+ C E G+ +++++ Sbjct: 369 WTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 >5M2E-A nrPDB Length = 418 Score = 365 bits (938), Expect = e-101, Method: Composition-based stats. Identities = 104/440 (23%), Positives = 176/440 (40%), Gaps = 77/440 (17%) Query: 10 RTVKVPATFRAVSKQSLAPFRVRCAVASPGKKRYTITLLPGDGIGPEVVSIAKNVLQQAG 69 + ++VPAT ++ V ++ K I + GDGIG ++ + V+ A Sbjct: 4 QKIQVPATGDKIT--------VNADMSLSVPKNPIIPFIEGDGIGVDISPVMIKVVDAAV 55 Query: 70 SLE---GVEFNFREMPIGGAALDLVG--VPLPEETISAAKESDAVLLGAI-----GGYKW 119 + + E+ G A + LP+ET+ A ++ + G + GG + Sbjct: 56 EKAYKGERKIAWMEVYAGEKATQVYDQDTWLPQETLDAVRDYVVSIKGPLTTPVGGGIRS 115 Query: 120 DNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGG 179 N + +R L ++ RP + + VD+++ RE + Sbjct: 116 LN-----------VALRQQLDLYVCQRPVRWFEGV----PSPVKKPGDVDMVIFRENSED 160 Query: 180 IYFG------------------EPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA- 220 IY G E G+K E G + + R+ R A + A Sbjct: 161 IYAGVEWKAGSPEAEKVIKFLTEEMGVKKIRFTENCGIGIKPVSQEGTKRLVRKALQYAV 220 Query: 221 RKRRGKLCSVDKANVLEAS-ILWRKRVTALASEY--------------------PDVELS 259 R + V K N+++ + ++ +A + +V + Sbjct: 221 DNDRSSVTLVHKGNIMKFTEGAFKDWGYEVARDEFGAELLDGGPWMQFKNPKTGKNVVVK 280 Query: 260 HMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEP 319 + D Q++ P ++D I T N+ GD LSD + G IG+ P A+LSDS +FE Sbjct: 281 DVIADAMLQQILLRPAEYDVIATLNLNGDYLSDALAAEVGGIGIAPGANLSDS-VAMFEA 339 Query: 320 IHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDI--Y 377 HG+AP AGQDK NP + ILSA M+L++ +G +AA I A+ T D Sbjct: 340 THGTAPKYAGQDKVNPGSLILSAEMMLRH-MGWTEAADLIIKGTNGAIAAKTVTYDFERL 398 Query: 378 SAGTKLVGCKEMGEEVLKSV 397 G L+ C E G+ ++ + Sbjct: 399 MDGATLLSCSEFGDAMIAKM 418 >1HQS-A nrPDB Length = 423 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 101/421 (23%), Positives = 167/421 (39%), Gaps = 80/421 (19%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLE---GVEFNFREMPIGGAALDLVGVPLPEE 98 I + GDG GP++ + A VL+ A + ++E+ G A + G LP E Sbjct: 19 NPIIPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEVYAGEKAYNKTGEWLPAE 78 Query: 99 TISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQ 153 T+ +E + G + GG + N + +R L +F LRP Sbjct: 79 TLDVIREYFIAIKGPLTTPVGGGIRSLN-----------VALRQELDLFVCLRPVRYFTG 127 Query: 154 LVDASTLKREVAEGVDLMVVRELTGGIYFGEPRG------------------IKTNENGE 195 + + E D+++ RE T IY G + E Sbjct: 128 V----PSPVKRPEDTDMVIFRENTEDIYAGIEYAKGSEEVQKLISFLQNELNVNKIRFPE 183 Query: 196 EVGFNTEVYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLEAS-ILWRKRVTALA-SE 252 G + + R+ R A + A R + V K N+++ + ++ LA E Sbjct: 184 TSGIGIKPVSEEGTSRLVRAAIDYAIEHGRKSVTLVHKGNIMKFTEGAFKNWGYELAEKE 243 Query: 253 YPD--------------------------------VELSHMYVDNAAMQLVRDPKQFDTI 280 Y D + + D Q++ P +FD + Sbjct: 244 YGDKVFTWAQYDRIAEEQGKDAANKAQSEAEAAGKIIIKDSIADIFLQQILTRPNEFDVV 303 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLS-DSGPGLFEPIHGSAPDIAGQDKANPLATI 339 T N+ GD +SD + G IG+ P A+++ ++G +FE HG+AP AG DK NP + I Sbjct: 304 ATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLDKVNPSSVI 363 Query: 340 LSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIY--SAGTKLVGCKEMGEEVLKSV 397 LS +LL++ LG +AA + ++ + + T D G V C E GEE++K++ Sbjct: 364 LSGVLLLEH-LGWNEAADLVIKSMEKTIASKVVTYDFARLMDGATEVKCSEFGEELIKNM 422 Query: 398 D 398 D Sbjct: 423 D 423 >2E5M-A nrPDB Length = 409 Score = 362 bits (928), Expect = e-100, Method: Composition-based stats. Identities = 115/397 (28%), Positives = 188/397 (47%), Gaps = 51/397 (12%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSL---EGVEFNFREMPIGGAALDLVGVPLPEE 98 + I + GDGIGPE+ + A V+ +A E + E+ G A LV P+E Sbjct: 24 KPVILYIEGDGIGPEITNAAIKVINKAVERAYGSSREIKWLEVYAGEKAEKLVNDRFPKE 83 Query: 99 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS 158 T + VL G + + + IR L ++AN+RP + L S Sbjct: 84 TQEMLLKYRVVLKGPLE------TPIGKGWKSVNVAIRLMLDLYANIRPVKYIEGLE--S 135 Query: 159 TLKREVAEGVDLMVVRELTGGIYFGEP---------------RGIKTNENGEEVGFNTEV 203 LK E VD+++ RE T +Y G R E ++ G +V Sbjct: 136 PLKH--PEKVDMIIFRENTDDLYRGIEYPFNSEEAKKIRDFLRKELKVEIEDDTGIGIKV 193 Query: 204 YAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLEAS-ILWRKRVTALA-SEYPD----- 255 + ++ RI R+A + A +R K+ + K NV++ + +R+ +A EY D Sbjct: 194 MSKYKTQRITRLAIQYAIEHKRKKVTIMHKGNVMKYTEGAFREWAYEVALKEYRDFIVTE 253 Query: 256 ------------VELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGM 303 + L+ DN Q++ P+++D I+ N+ GD +SD A + G+IGM Sbjct: 254 EEINQGKPDQGKIILNDRIADNMFQQIIIRPEEYDIILAPNVNGDYISDAAGALIGNIGM 313 Query: 304 LPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAV 363 L A++ D G G+FE IHG+AP AG++ ANP I + ++L++ +G +AA IE A+ Sbjct: 314 LGGANIGDEG-GMFEAIHGTAPKYAGKNVANPTGIIKAGELMLRW-MGWNEAADLIEKAI 371 Query: 364 LVALNNGFRTGDIYS-AGTKLVGCKEMGEEVLKSVDS 399 +A+ + T DI G K +G KE +E++K +D+ Sbjct: 372 NMAIRDKKVTQDIARFMGVKALGTKEYADELIKIMDT 408 >5YVT-A nrPDB Length = 339 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 106/361 (29%), Positives = 174/361 (48%), Gaps = 34/361 (9%) Query: 44 TITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGV--PLPEETIS 101 T+TL+PGDGIGPE+ + + A + + E + A+ G +P E Sbjct: 6 TVTLIPGDGIGPEISAAVMKIFDAAKA----PIQWEERNV--TAIQGPGGKWMIPSEAKE 59 Query: 102 AAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLK 161 + ++ L G + L +R ++AN+RP + T Sbjct: 60 SMDKNKMGLKGPL------KTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYT-- 111 Query: 162 REVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETAR 221 V+++ +RE T G Y G I + V + ++ RIA AFE AR Sbjct: 112 -----DVNIVTIRENTEGEYSGIEHVI-----VDGVVQSIKLITEGASKRIAEFAFEYAR 161 Query: 222 K-RRGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDT 279 R + +V KAN++ + L+ ++ +A D++ + MY+D + +V+DP QFD Sbjct: 162 NNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDV 221 Query: 280 IVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATI 339 +V N++GDILSD + + G +G+ PS ++ +G +FE +HG+APDIAG+D ANP A + Sbjct: 222 LVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALL 281 Query: 340 LSAAMLLKYGLGEEKAAKRIEDAVLVALNNGF-RTGDIYSAGTKLVGCKEMGEEVLKSVD 398 LSA M+L++ +G A RIE A + +G T D+ C + EE+ + V Sbjct: 282 LSAVMMLRH-MGLFDHAARIEAACFATIKDGKSLTKDLGGNAK----CSDFTEEICRRVK 336 Query: 399 S 399 Sbjct: 337 D 337 >3DMS-A nrPDB Length = 427 Score = 358 bits (920), Expect = 2e-99, Method: Composition-based stats. Identities = 99/413 (23%), Positives = 168/413 (40%), Gaps = 69/413 (16%) Query: 38 PGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLE---GVEFNFREMPIGGAALDLVG-- 92 + I + GDG G ++ + V+ A + ++ E+ G A + G Sbjct: 32 NVSDQPIIPYIEGDGTGFDITPVMIKVVDAAVEKAYGGKKKIHWMEIYAGEKATKVYGPD 91 Query: 93 VPLPEETISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRP 147 V LPEET+ KE + G + GG + N + +R L ++ LRP Sbjct: 92 VWLPEETLQVLKEYVVSIKGPLTTPVGGGIRSLN-----------VALRQELDLYVCLRP 140 Query: 148 ATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFG------------------EPRGIK 189 + E ++++ RE + IY G E G+K Sbjct: 141 IQYFKGV----PSPVREPEKTNMVIFRENSEDIYAGIEWAAESEQAKKVIKFLQEEMGVK 196 Query: 190 TNENGEEVGFNTEVYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLEAS-ILWRKRVT 247 + G + + +R+ R A + A R + V K N+++ + +R Sbjct: 197 KIRFPQTSGIGIKPVSKEGTERLVRKAIQYAIDNDRKSVTLVHKGNIMKFTEGAFRDAGY 256 Query: 248 ALASEYP--------------------DVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFG 287 ALA + ++ + D Q++ P ++D I T N+ G Sbjct: 257 ALAQKEFGAELIDGGPWMKFKNPKTGNEIVVKDSIADAFLQQILLRPAEYDVIATLNLNG 316 Query: 288 DILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLK 347 D +SD + G IG+ P A+LSDS +FE HG+AP AG+D NP + ILSA M+L+ Sbjct: 317 DYISDALAAQVGGIGIAPGANLSDS-VAMFEATHGTAPKYAGKDYVNPGSEILSAEMMLR 375 Query: 348 YGLGEEKAAKRIEDAVLVALNNGFRTGDIY--SAGTKLVGCKEMGEEVLKSVD 398 + LG +AA I A+ ++ T D G V C G+ ++++++ Sbjct: 376 H-LGWTEAADVIISAMEKSIKQKRVTYDFARLMEGATQVSCSGFGQVLIENME 427 >3ASJ-A nrPDB Length = 334 Score = 358 bits (918), Expect = 3e-99, Method: Composition-based stats. Identities = 136/359 (37%), Positives = 187/359 (52%), Gaps = 30/359 (8%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 Y I L+ GDGIG EV+ A+ VL+ G+ F E G + G +PEET+ Sbjct: 3 YRICLIEGDGIGHEVIPAARRVLEAT----GLPLEFVEAEAGWETFERRGTSVPEETVEK 58 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKR 162 A L GA K + +R L ++AN+RPA P Sbjct: 59 ILSCHATLFGAATSP----TRKVPGFFGAIRYLRRRLDLYANVRPAKSRP--------VP 106 Query: 163 EVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARK 222 GVDL++VRE T G+Y + R +V V + +RI R A A Sbjct: 107 GSRPGVDLVIVRENTEGLYVEQERRYL------DVAIADAVISKKASERIGRAALRIAEG 160 Query: 223 R-RGKLCSVDKANVLEAS-ILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTI 280 R R L KANVL + L+ V +A ++P V + + VDN AMQLV P++FD I Sbjct: 161 RPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVI 220 Query: 281 VTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 VT N+ GDILSD A+ + G +G+ PS ++ D+ +FEP+HGSAPDIAG+ ANP A IL Sbjct: 221 VTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTT-AVFEPVHGSAPDIAGKGIANPTAAIL 279 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDS 399 SAAM+L Y LGE++AAKR+E AV + L G RT D+ T + E V++++ S Sbjct: 280 SAAMMLDY-LGEKEAAKRVEKAVDLVLERGPRTPDLGGDAT----TEAFTEAVVEALKS 333 >6C0E-A nrPDB Length = 419 Score = 355 bits (912), Expect = 1e-98, Method: Composition-based stats. Identities = 103/438 (23%), Positives = 171/438 (39%), Gaps = 77/438 (17%) Query: 12 VKVPATFRAVSKQSLAPFRVRCAVASPGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSL 71 +KVPA A++ + V I + GDGIG +V V+ A Sbjct: 7 IKVPAQGEAITVAADHSLHV--------PDNPIIPFIEGDGIGVDVTPPMIRVVDAAVQK 58 Query: 72 ---EGVEFNFREMPIGGAALDLVG--VPLPEETISAAKESDAVLLGAI-----GGYKWDN 121 + ++ E+ G A + G LP+ET+ A K+ + G + GG + N Sbjct: 59 AYGNKRKISWMEVYAGEKATKVYGGDQWLPKETLDAMKKYVVSIKGPLTTPVGGGIRSLN 118 Query: 122 NEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIY 181 + IR + ++ LRP + D+++ RE + IY Sbjct: 119 -----------VAIRQDMDLYVCLRPIRYFNGV----PSPVREPWKTDMVIFRENSEDIY 163 Query: 182 FG------------------EPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA-RK 222 G + G+K E G + + R+ + A + A Sbjct: 164 AGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSREGTTRLVKAAIQYAIDN 223 Query: 223 RRGKLCSVDKANVLE----ASILWRKRVTA---LASEY--------------PDVELSHM 261 R + V K N+++ A W +V A EY + ++ + Sbjct: 224 DRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWMEFKNPKTGKQIIINDV 283 Query: 262 YVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIH 321 D Q++ P+ + I T N+ GD +SD + G IG+ P A++SD +FE H Sbjct: 284 IADAFLQQILLRPEDYSVIATLNLNGDYISDALAAQVGGIGIAPGANISDQ-MAVFEATH 342 Query: 322 GSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDI--YSA 379 G+AP AGQ+K NP + ILSA M+L++ +G +AA I + A+ T D Sbjct: 343 GTAPKYAGQNKVNPGSIILSAEMMLRH-MGWYEAADLIIRGMEGAIEAKTVTYDFERGMQ 401 Query: 380 GTKLVGCKEMGEEVLKSV 397 G LV + ++K + Sbjct: 402 GATLVSSSGFADAMIKHM 419 >3FMX-X nrPDB Length = 364 Score = 355 bits (912), Expect = 2e-98, Method: Composition-based stats. Identities = 113/360 (31%), Positives = 178/360 (49%), Gaps = 10/360 (2%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDL-VGVPLPEETIS 101 + I +PGDGIG EV+ VL+ A G+ F L G +P++ Sbjct: 6 FRIAAIPGDGIGLEVLPEGIRVLEAAALKHGLALEFDTFEWASCDYYLQHGKMMPDDWAE 65 Query: 102 AAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLK 161 K+ DA+ GA+G D H+ LL+ R + N+RP + P + L Sbjct: 66 QLKQYDAIYFGAVGWP--DKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPGV--PCALA 121 Query: 162 REVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETAR 221 +D +VVRE T G Y GI E+ ++ +DRI + AF+ A Sbjct: 122 NRKVGDIDFVVVRENTEGEYSSL-GGIMFENTENEIVIQESIFTRRGVDRILKYAFDLAE 180 Query: 222 KR-RGKLCSVDKANVLEASI-LWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDT 279 KR R + S K+N + S+ W KR A+A+ YP V ++D + V P++FD Sbjct: 181 KRERKHVTSATKSNGMAISMPYWDKRTEAMAAHYPHVSWDKQHIDILCARFVLQPERFDV 240 Query: 280 IVTNNIFGDILSDEASMITGSIGMLPSASLSD--SGPGLFEPIHGSAPDIAGQDKANPLA 337 +V +N+FGDILSD G+IG+ PSA+L+ + P LFEP+HGSAPDI G++ ANP+A Sbjct: 241 VVASNLFGDILSDLGPACAGTIGIAPSANLNPERNFPSLFEPVHGSAPDIFGKNIANPIA 300 Query: 338 TILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 397 I S A++L++ ++ +R D +L A+ G + + +++G + ++ Sbjct: 301 MIWSGALMLEFLGQGDERYQRAHDDMLNAIERVIADGSVTPDMGGTLSTQQVGAAISDTL 360 >3TY3-A nrPDB Length = 366 Score = 344 bits (882), Expect = 4e-95, Method: Composition-based stats. Identities = 114/385 (29%), Positives = 193/385 (50%), Gaps = 39/385 (10%) Query: 34 AVASPGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGV 93 + + +R + L+P DGIG EVV A+ +++ + ++F+F ++ G + G Sbjct: 2 STSMSATRRIVLGLIPADGIGKEVVPAARRLMENLPAKHKLKFDFIDLDAGWGTFERTGK 61 Query: 94 PLPEETISAAK-ESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLP 152 LPE T+ K E +A L GA+ K ++ +R + ++AN+RP L Sbjct: 62 ALPERTVERLKTECNAALFGAVQSP----THKVAGYSSPIVALRKKMGLYANVRPVKSLD 117 Query: 153 QLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRI 212 + VDL++VRE T +Y E R + N G+ V + +I Sbjct: 118 G---------AKGKPVDLVIVRENTECLYVKEERMV-QNTPGKRVAEAIRRISEEASTKI 167 Query: 213 ARVAFETARKRRG-------------KLCSVDKANVLEAS-ILWRK---RVTALASEYPD 255 ++AFE A+ R+ + + K+NV+ + L+R+ +L Y Sbjct: 168 GKMAFEIAKSRQKIRESGTYSIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYAS 227 Query: 256 VELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPG 315 + + VD+ +L R+P+ FD +V N++GDILSD A+ + GS+G++PSA++ D+ Sbjct: 228 INVDEQIVDSMVYRLFREPECFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGDNFV- 286 Query: 316 LFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFR-TG 374 + EP+HGSAPDIAG+ ANP+AT S A++L++ +G + AA I AV L G T Sbjct: 287 MSEPVHGSAPDIAGRGIANPVATFRSVALMLEF-MGHQDAAADIYTAVDKVLTEGKVLTP 345 Query: 375 DIYSAGTKLVGCKEMGEEVLKSVDS 399 D+ G E+ + VL ++ + Sbjct: 346 DLGGKS----GTNEITDAVLANIHN 366 >4Y1P-A nrPDB Length = 337 Score = 344 bits (882), Expect = 4e-95, Method: Composition-based stats. Identities = 124/367 (33%), Positives = 190/367 (51%), Gaps = 41/367 (11%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 + + L+ GDGIGPEVVS +K +L + + + E+ G + G LP++++ Sbjct: 3 FVVALIQGDGIGPEVVSKSKTILARLNEKFSLPIEYIEVEAGDTTKNKFGDALPKDSLRV 62 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKR 162 +++D +L G +G D ++++R ++ANLRPA LP L + Sbjct: 63 IEKADMILKGPVGETAADV----------VVKLRLMYDLYANLRPAKSLPGLENKFG--- 109 Query: 163 EVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARK 222 VD++VVRE T +Y G I + V +V RIA+VA A + Sbjct: 110 ----DVDILVVRENTEDLYKGLEHVI-----SDGVTVGIKVITRAASTRIAQVALNQALR 160 Query: 223 RRGKLCSVDKANVLEAS-ILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIV 281 R+ K+ V K+NV+ + L+ + + VE S MYVD AA LVR+P+ FD IV Sbjct: 161 RKKKVVCVHKSNVMRITDGLFAESCRNVLK--GKVEYSEMYVDAAAANLVRNPQAFDVIV 218 Query: 282 TNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILS 341 T N +GDILSDEA I GS+G+ PSA++ D LFEP+HG+A DIAG++ ANP A +LS Sbjct: 219 TENTYGDILSDEAGQIAGSLGISPSANIGDR-KSLFEPVHGAAFDIAGKNIANPTAFLLS 277 Query: 342 AAMLLKY------GLGEEKAAKRIEDAVLVALNNG-FRTGDIYSAGTKLVGCKEMGEEVL 394 M+L + AAK + DA+ + G + T D VG +E++ Sbjct: 278 VGMMLDRMQELSGDIRYNNAAKSLRDAIYSVYSEGKYLTPD--------VGGSSTTDEMI 329 Query: 395 KSVDSQV 401 ++ S++ Sbjct: 330 SAIRSKI 336 >1XGV-A nrPDB Length = 435 Score = 343 bits (881), Expect = 6e-95, Method: Composition-based stats. Identities = 99/400 (24%), Positives = 164/400 (41%), Gaps = 55/400 (13%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLE---GVEFNFREMPIGGAALDLVGVPLPEE 98 + + GDG+GPEVV A V+ A + E+ G A + G LP+ Sbjct: 35 NPVVAFIRGDGVGPEVVESALKVVDAAVKKVYGGSRRIVWWELLAGHLAREKCGELLPKA 94 Query: 99 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS 158 T+ + + L G + + IR AL ++AN+RP Q Sbjct: 95 TLEGIRLARVALKGPLE------TPVGTGYRSLNVAIRQALDLYANIRPVRYYGQ----- 143 Query: 159 TLKREVAEGVDLMVVRELTGGIYFGEP-----------RGIKTNENG----EEVGFNTEV 203 + A+ VD+++ RE T +Y G R E G E+ G + Sbjct: 144 PAPHKYADRVDMVIFRENTEDVYAGIEWPHDSPEAARIRRFLAEEFGISIREDAGIGVKP 203 Query: 204 YAAHEIDRIARVAFETARKRRGKL-CSVDKANVLE----ASILWRKRVT----------- 247 + R+ A E A + + + K N+++ A + W V Sbjct: 204 ISRFATRRLMERALEWALRNGNTVVTIMHKGNIMKYTEGAFMRWAYEVALEKFREHVVTE 263 Query: 248 -ALASEYPDVE------LSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGS 300 + +Y V ++ DN Q++ P + IV N+ GD +SD AS + G Sbjct: 264 QEVQEKYGGVRPEGKILVNDRIADNMLQQIITRPWDYQVIVAPNLNGDYISDAASALVGG 323 Query: 301 IGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIE 360 IGM ++ D G + EP+HG+AP AG+D NP A ILSA++L+ +G + +E Sbjct: 324 IGMAAGMNMGD-GIAVAEPVHGTAPKYAGKDLINPSAEILSASLLIGEFMGWREVKSIVE 382 Query: 361 DAVLVALNNGFRTGDI--YSAGTKLVGCKEMGEEVLKSVD 398 A+ A+ + T D+ + G + + E E ++ +D Sbjct: 383 YAIRKAVQSKKVTQDLARHMPGVQPLRTSEYTETLIAYID 422 >2D1C-A nrPDB Length = 496 Score = 343 bits (880), Expect = 8e-95, Method: Composition-based stats. Identities = 123/364 (33%), Positives = 187/364 (51%), Gaps = 33/364 (9%) Query: 41 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVP--LPEE 98 R IT++PGDGIGPE V VL+ A + E+ GA++ G+ +P+E Sbjct: 18 GRKLITVIPGDGIGPECVEATLKVLEAAKAPLA-----YEVREAGASVFRRGIASGVPQE 72 Query: 99 TISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDAS 158 TI + +++ VL G + + + +R + +AN+RP P + Sbjct: 73 TIESIRKTRVVLKGPLE------TPVGYGEKSANVTLRKLFETYANVRPVREFPNVPTPY 126 Query: 159 TLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFE 218 G+DL+VVRE +Y G V ++ + ++I R AFE Sbjct: 127 A-----GRGIDLVVVRENVEDLYAGIEHM-----QTPSVAQTLKLISWKGSEKIVRFAFE 176 Query: 219 TARKR-RGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQ 276 AR R K+ K+N+++ A ++ +A EYPD+E H+ VDNAA QLV+ P+Q Sbjct: 177 LARAEGRKKVHCATKSNIMKLAEGTLKRAFEQVAQEYPDIEAVHIIVDNAAHQLVKRPEQ 236 Query: 277 FDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPL 336 F+ IVT N+ GDILSD S + G +G PSA++ + +FE +HGSAP AG++ NP Sbjct: 237 FEVIVTTNMNGDILSDLTSGLIGGLGFAPSANIGNE-VAIFEAVHGSAPKYAGKNVINPT 295 Query: 337 ATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFR-TGDI--YSAGTKLVGCKEMGEEV 393 A +LSA M+L+Y L E A IE+A+L L G TGD+ Y G K E E + Sbjct: 296 AVLLSAVMMLRY-LEEFATADLIENALLYTLEEGRVLTGDVVGYDRGAK---TTEYTEAI 351 Query: 394 LKSV 397 ++++ Sbjct: 352 IQNL 355 >1WPW-A nrPDB Length = 336 Score = 340 bits (871), Expect = 9e-94, Method: Composition-based stats. Identities = 117/367 (31%), Positives = 190/367 (51%), Gaps = 41/367 (11%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 +T+ L+ GDGIGPE+VS +K +L + L + + E+ G AL G LP++++ Sbjct: 2 FTVALIQGDGIGPEIVSKSKRILAKINELYSLPIEYIEVEAGDRALARYGEALPKDSLKI 61 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKR 162 ++D +L G +G D ++++R ++AN+RPA +P + Sbjct: 62 IDKADIILKGPVGESAADV----------VVKLRQIYDMYANIRPAKSIPGIDTKYG--- 108 Query: 163 EVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARK 222 VD+++VRE T +Y G + + V ++ +RIA+V A + Sbjct: 109 ----NVDILIVRENTEDLYKGFEHIV-----SDGVAVGMKIITRFASERIAKVGLNFALR 159 Query: 223 RRGKLCSVDKANVLEAS-ILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIV 281 RR K+ V KANV+ + L+ + ++ VE S MYVD AA LVR+P+ FD IV Sbjct: 160 RRKKVTCVHKANVMRITDGLFAEACRSVLK--GKVEYSEMYVDAAAANLVRNPQMFDVIV 217 Query: 282 TNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILS 341 T N++GDILSDEAS I GS+G+ PSA++ D LFEP+HG+A DIAG++ NP A +LS Sbjct: 218 TENVYGDILSDEASQIAGSLGIAPSANIGDK-KALFEPVHGAAFDIAGKNIGNPTAFLLS 276 Query: 342 AAMLLK--YGLGEEKAAKRIEDAVLVAL-----NNGFRTGDIYSAGTKLVGCKEMGEEVL 394 +M+ + Y L + + A+ A+ T D VG ++++ Sbjct: 277 VSMMYERMYELSNDDRYIKASRALENAIYLVYKERKALTPD--------VGGNATTDDLI 328 Query: 395 KSVDSQV 401 + +++ Sbjct: 329 NEIYNKL 335 >2D4V-A nrPDB Length = 429 Score = 337 bits (864), Expect = 5e-93, Method: Composition-based stats. Identities = 99/421 (23%), Positives = 170/421 (40%), Gaps = 82/421 (19%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLE---GVEFNFREMPIGGAALDLVGV--PLP 96 + I + GDGIG +V ++V+ A + + + E+ G A+ L G LP Sbjct: 26 QPIIPFIEGDGIGCDVTPAMRSVVDAAVAKVYGGQRQIAWMELFAGQKAVQLYGEGQYLP 85 Query: 97 EETISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVL 151 +ET++A +E + G + GG + N + +R L ++ LRP Sbjct: 86 DETMAAIREYKVAIKGPLETPVGGGIRSLN-----------VAMRQDLDLYVCLRPVRYF 134 Query: 152 PQLVDASTLKREVAEGVDLMVVRELTGGIYFG------------------EPRGIKTNEN 193 + E VD+++ RE + IY G E G+ Sbjct: 135 EG----TPSPMRHPEKVDMVIFRENSEDIYAGIEWPAGSPEAEKIIRFLREEMGVTKIRF 190 Query: 194 GEEVGFNTEVYAAHEIDRIARVAFETARKRRG-KLCSVDKANVLEASI------------ 240 + + + +R+ R + A + + V K N+++ + Sbjct: 191 PDSSAIGIKPVSTEGSERLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGGFRDWGYALAE 250 Query: 241 --------LWRKRVTALASEYP--------------DVELSHMYVDNAAMQLVRDPKQFD 278 WR++ +E + + + DN Q++ P+ + Sbjct: 251 REFAGRVFTWRQKAAISKAEGKAAGQKAEQQAIADGKLIIKDVIADNFLQQILLRPEDYS 310 Query: 279 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT 338 + T N+ GD +SD + G IGM P A+LSD+ +FE HG+APDIAGQ KANP + Sbjct: 311 VVATLNLNGDYVSDALAAEVGGIGMAPGANLSDTH-AIFEATHGTAPDIAGQGKANPSSL 369 Query: 339 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIY--SAGTKLVGCKEMGEEVLKS 396 ILSA M+L++ LG +AA+ I A+ + G TGD+ + E +++ Sbjct: 370 ILSAVMMLEH-LGWGEAAQAIVAAMNATIAAGEVTGDLAALRGDVPALSTTEFTAALIRR 428 Query: 397 V 397 Sbjct: 429 F 429 >3BLV-B nrPDB Length = 354 Score = 337 bits (864), Expect = 6e-93, Method: Composition-based stats. Identities = 116/395 (29%), Positives = 184/395 (46%), Gaps = 50/395 (12%) Query: 11 TVKVPATFRAVSKQSLAPFRVRCAVASPGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGS 70 TVK P+ R K +P +YT++ + GDGIGPE+ K + A Sbjct: 2 TVKQPSIGRYTGK------------PNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAAN- 48 Query: 71 LEGVEFNFREMPIGGAALDLVG-VPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPE 129 V + + + + G +P+ + + ++ L G + Sbjct: 49 ---VPIEWESCDVS--PIFVNGLTTIPDPAVQSITKNLVALKGPLA------TPIGKGHR 97 Query: 130 KGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIK 189 L +R +FAN+RPA + E VDL+++RE T G Y G + Sbjct: 98 SLNLTLRKTFGLFANVRPAKSIEGFKTTY-------ENVDLVLIRENTEGEYSGIEHIVC 150 Query: 190 TNENGEEVGFNTEVYAAHEIDRIARVAFETARK-RRGKLCSVDKANVLE-ASILWRKRVT 247 V + ++ +R+ R AFE AR R ++ V K+ + A L+ Sbjct: 151 -----PGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAK 205 Query: 248 ALASEYPDVELSHMYVDNAAMQLVRDPKQFD--TIVTNNIFGDILSDEASMI-TGSIGML 304 L+ EYPD+ L +DN+ +++V +P + V N++GDILSD S + GS+G+ Sbjct: 206 ELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLT 265 Query: 305 PSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVL 364 PSA++ +FE +HGSAPDIAGQDKANP A +LS+ M+L + +G A +I++AVL Sbjct: 266 PSANIGHK-ISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNH-MGLTNHADQIQNAVL 323 Query: 365 VALNNG--FRTGDIYSAGTKLVGCKEMGEEVLKSV 397 + +G RTGD+ T E V+K + Sbjct: 324 STIASGPENRTGDLAGTAT----TSSFTEAVIKRL 354 >5GRH-B nrPDB Length = 354 Score = 331 bits (849), Expect = 3e-91, Method: Composition-based stats. Identities = 103/380 (27%), Positives = 184/380 (48%), Gaps = 39/380 (10%) Query: 22 SKQSLAPFRVRCAVASPGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREM 81 S+Q++ P ++ R+T+T++PGDGIGPE++ K+V + A V +F E+ Sbjct: 2 SEQTIPP-------SAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHAC----VPVDFEEV 50 Query: 82 PIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKV 141 + A D + I A + + L G I N + + +R +L + Sbjct: 51 HVSSNA-DEEDI---RNAIMAIRRNRVALKGNIE--TNHNLPPSHKSRNNI--LRTSLDL 102 Query: 142 FANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNT 201 +AN+ LP +V + +D+++VRE T G Y +E+ V + Sbjct: 103 YANVIHCKSLPGVVTRH-------KDIDILIVRENTEGEYSS-----LEHESVAGVVESL 150 Query: 202 EVYAAHEIDRIARVAFETARKR-RGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELS 259 ++ + RIA AF+ A++ R K+ +V KAN+++ L+ + +A+ YP + Sbjct: 151 KIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFE 210 Query: 260 HMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEP 319 +M VDN MQLV P+QFD +V N++G+I+++ + + G G++ A+ Sbjct: 211 NMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETA 270 Query: 320 IHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNN-GFRTGDIYS 378 + IA ++ ANP AT+L++ M+L + L A I AVL +++N T DI Sbjct: 271 TRNTGKSIANKNIANPTATLLASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIGG 329 Query: 379 AGTKLVGCKEMGEEVLKSVD 398 GT E ++V++ + Sbjct: 330 QGT----TSEAIQDVIRHIR 345 >3BLX-A nrPDB Length = 349 Score = 324 bits (831), Expect = 4e-89, Method: Composition-based stats. Identities = 103/369 (27%), Positives = 173/369 (46%), Gaps = 46/369 (12%) Query: 41 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPE--- 97 R+T+TL+PGDG+G E+ + + + +PI +++ E Sbjct: 16 GRFTVTLIPGDGVGKEITDSVRTIFEA-----------ENIPIDWETINIKQTDHKEGVY 64 Query: 98 ETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDA 157 E + + K + L G W + +R L ++AN+ L + Sbjct: 65 EAVESLKRNKIGLKGL-----WHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTR 119 Query: 158 STLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAF 217 +DL+V+RE T G + G +E+ V + +V + +RIAR AF Sbjct: 120 IP-------DIDLIVIRENTEGEFSG-----LEHESVPGVVESLKVMTRPKTERIARFAF 167 Query: 218 ETARK-RRGKLCSVDKANVLE-ASILWRKRVTALA-SEYPDVELSHMYVDNAAMQLVRDP 274 + A+K R + +V KAN+++ L+R +T + EYPD+++S + VDNA+MQ V P Sbjct: 168 DFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKP 227 Query: 275 KQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAP---DIAGQD 331 QFD +VT +++G IL + + + G G++ A+ +FEP GS DI GQ+ Sbjct: 228 HQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDY-AVFEP--GSRHVGLDIKGQN 284 Query: 332 KANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFR-TGDIYSAGTKLVGCKEMG 390 ANP A ILS+ ++L + LG + A RI AV + G T DI + + Sbjct: 285 VANPTAMILSSTLMLNH-LGLNEYATRISKAVHETIAEGKHTTRDIGGSS----STTDFT 339 Query: 391 EEVLKSVDS 399 E++ + + Sbjct: 340 NEIINKLST 348 >2G4O-A nrPDB Length = 337 Score = 315 bits (807), Expect = 2e-86, Method: Composition-based stats. Identities = 126/357 (35%), Positives = 184/357 (51%), Gaps = 25/357 (7%) Query: 44 TITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAA 103 + ++ GDGIGPEV + A VL +G G LP+ ++ Sbjct: 3 KLAIIAGDGIGPEVTAEAVKVLDAVVP----GVQKTSYDLGARRFHATGEVLPDSVVAEL 58 Query: 104 KESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKRE 163 + DA+LLGAIG + L L NLRPA + P + AS L Sbjct: 59 RNHDAILLGAIGDPSVPSGVLERGLLLRLRF---ELDHHINLRPARLYPGV--ASPLSGN 113 Query: 164 VAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKR 223 G+D +VVRE T G Y G I+ EV V A + R+ AFE AR+R Sbjct: 114 --PGIDFVVVREGTEGPYTGNGGAIRVGT-PNEVATEVSVNTAFGVRRVVADAFERARRR 170 Query: 224 RGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVT 282 R L V K NVL A LW + V + YPDVE+++ +VD A + ++ DP +FD IVT Sbjct: 171 RKHLTLVHKTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVT 230 Query: 283 NNIFGDILSDEASMITGSIGMLPSASL--SDSGPGLFEPIHGSAPDIAGQDKANPLATIL 340 +N+FGDI++D A+ + G IG+ S ++ + + P +FEP+HGSAPDIAGQ A+P A I+ Sbjct: 231 DNLFGDIITDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIM 290 Query: 341 SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 397 S A+LL + LGE AA R++ AV + + G++ + ++GE + ++ Sbjct: 291 SVALLLSH-LGEHDAAARVDRAVEA---------HLATRGSERLATSDVGERIAAAL 337 >5HN5-A nrPDB Length = 353 Score = 309 bits (792), Expect = 1e-84, Method: Composition-based stats. Identities = 119/360 (33%), Positives = 179/360 (49%), Gaps = 37/360 (10%) Query: 43 YTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISA 102 Y + ++PGDGIGPEV+ A VL+ V F + E G G P+ EE + Sbjct: 2 YRVAVIPGDGIGPEVIDGAVRVLKAVTGR--VRFEYYEG--GVDVFQECGSPIREEDLEE 57 Query: 103 AKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKR 162 + SDAVL GA +L +R L ++ANLR + Sbjct: 58 IRRSDAVLFGATTTP-----FDLPGYRSLILTLRKELGLYANLR-------------IIP 99 Query: 163 EVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARK 222 ++ G ++++VRE + G+YFG + + + +RIAR A E A+ Sbjct: 100 DLRTGREIVIVRENSEGLYFGIGAVV------NGRAVDVRLITREGAERIARFAVEQAKA 153 Query: 223 RRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVT 282 R + V KANVL +R+ V +A E VE+ +D+ ++LVR+P + I++ Sbjct: 154 RGSFITFVHKANVLTGDKFFRRIVREVAGE-EGVEVRDAIIDSFTIKLVRNPWEHGVILS 212 Query: 283 NNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSA 342 N+FGDILSD A++ GSIG++PS + D G LFEP+HGSAPDIAG+ ANP+ ILS Sbjct: 213 ENLFGDILSDLATVHAGSIGIVPSGNYGD-GIALFEPVHGSAPDIAGKGIANPIGAILSG 271 Query: 343 AMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDSQVP 402 AMLL Y LG + I AV + NG T D+ +++ ++ ++ + Sbjct: 272 AMLLDY-LGLD--GSLIRAAVRGYVVNGELTPDMGGRA----RTEDVVRGIIGEIEDLLS 324 >4AOY-A nrPDB Length = 402 Score = 150 bits (378), Expect = 1e-36, Method: Composition-based stats. Identities = 73/407 (17%), Positives = 141/407 (34%), Gaps = 56/407 (13%) Query: 39 GKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEE 98 K + + L+ DG E+ I ++++ +E N +G D + + Sbjct: 2 SKIKMKVPLVEMDG--DEMTRIIWRLIKENLLEPYIELNTEYYDLGLENRDKTEDQVTID 59 Query: 99 TISAAKESDAVLLGAIGGY---KWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLV 155 A ++ + A + + + IRA L P + Sbjct: 60 AARAIQKYGVGVKCATITPNAQRVEEYNLKKMWKSPNGTIRAILDGTVFRAPIV----VN 115 Query: 156 DASTLKREVAEGVDLMVVRELTGGIY---------FGEPRGIKTNENGEEVGFNTEVY-- 204 + + + + R G +Y G+ + T+ENGE + Sbjct: 116 SIKPFVKGWKKPIS--IARHAYGDVYKNVEYYVPSAGKAELVFTSENGEVSRQTIHEFDG 173 Query: 205 ---------AAHEIDRIARVAFETARKRRGKLCSVDKANVLEA-SILWRKRVTALAS--- 251 I AR F A L K + + ++ + Sbjct: 174 PGVIMGMHNTDKSIRSFARACFNYALDMNQDLWFSTKDTISKTYDHRFKDIFQEIYENEY 233 Query: 252 ----EYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 307 E +++ + +D+A +++R N GD++SD + GS+ M+ S Sbjct: 234 KEKFEAKNLQYFYTLIDDAVARIIRSEGGM-VWACKNYDGDVMSDMVASAFGSLAMMTSV 292 Query: 308 SLSDSGPGLFEPIHGSA-----PDIAGQDKA-NPLATILSAAMLLKY-----GLGE-EKA 355 +S G FE HG+ + G++ + N +ATI + LK G+ E Sbjct: 293 LVSPDGKYEFEAAHGTVTRHYYKHLKGEETSTNSMATIFAWTGALKKRGELDGIKELVDF 352 Query: 356 AKRIEDAVLVALNNGFRTGDIYSAG----TKLVGCKEMGEEVLKSVD 398 A ++E A + + NG T D+ S K+V ++ +E+ K+ + Sbjct: 353 ATKLEQASVQTIENGVMTKDLASLSEVPEKKIVNTEDFLKEIRKTFE 399 >1ZOR-A nrPDB Length = 399 Score = 138 bits (347), Expect = 6e-33, Method: Composition-based stats. Identities = 70/389 (17%), Positives = 135/389 (34%), Gaps = 51/389 (13%) Query: 54 GPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGA 113 G E+ + ++++ L ++ +G D + E A K+ + A Sbjct: 15 GDEMARVMWKMIKEKLILPYLDIQLVYFDLGIKKRDETDDQITIEAAKAIKKYGVGVKCA 74 Query: 114 IGGY---KWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDL 170 + + IRA L +P + + L + + + Sbjct: 75 TITPDAERVKEYNLKKAWKSPNATIRAYLDGTVFRKPIM----VKNVPPLVKRWKKP--I 128 Query: 171 MVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYA------------------AHEIDRI 212 ++ R G IY ++ E V N E I Sbjct: 129 IIGRHAYGDIYNAVEAKVEGPAEVELVVRNKENKTLLVHKFEGNGVVMAMHNLEKSIRSF 188 Query: 213 ARVAFETARKRRGKLCSVDKANVLEAS-----ILWRKRVTALASEY--PDVELSHMYVDN 265 A+ A + + K + + ++++ V E V +M +D+ Sbjct: 189 AQSCINYAISEKVDIWFATKDTISKVYHAYFKDIFQEEVDKRKEELEKAGVNYRYMLIDD 248 Query: 266 AAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAP 325 AA Q++R N GDI+SD + GS+G++ S +S G FE HG+ Sbjct: 249 AAAQILRSEGGM-LWACMNYEGDIMSDMIASGFGSLGLMTSVLVSPDGVYEFEAAHGTVR 307 Query: 326 D-----IAGQDKA-NPLATILSAAMLLKYGLGEE------KAAKRIEDAVLVALNNGFRT 373 + G+ + NP A+I + ++ + + A ++E AV+ + +G T Sbjct: 308 RHYYRYLKGEKTSTNPTASIFAWTGAIRKRGELDGTPEVCEFADKLEKAVINTIESGVIT 367 Query: 374 GDIY----SAGTKLVGCKEMGEEVLKSVD 398 D+ K V +E +EV K+++ Sbjct: 368 KDLQPFTEPPIDKYVTLEEFIDEVKKNLE 396 >2UXQ-A nrPDB Length = 402 Score = 124 bits (311), Expect = 7e-29, Method: Composition-based stats. Identities = 70/405 (17%), Positives = 142/405 (35%), Gaps = 58/405 (14%) Query: 42 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETIS 101 + L+ DG E+ + +++ L ++ +G D + + Sbjct: 4 QMKTPLVELDG--DEMTRVLWPLIKDKLLLPFIDLQTEYYDLGIEERDRTNDQITIDAAE 61 Query: 102 AAKESDAVLLGAIGGYKWDNNEKHLRPEK---GLLQIRAALKVFANLRPATVLPQLVDAS 158 A K+ + A D E++ E+ +RA L +P + + Sbjct: 62 AIKKYGVGVKNATITPNQDRVEEYGLKEQWKSPNATVRAMLDGTVFRKPIM----VKNIK 117 Query: 159 TLKREVAEGVDLMVVRELTGGIYF---------GEPRGIKTNENGEEVGFNTEVYAAHEI 209 R + ++V R G Y G+ + T++NG+E I Sbjct: 118 PSVRSWQKP--IVVGRHAYGDFYKNAEIFAEAGGKLEIVVTDKNGKETRQTIMEVDEPAI 175 Query: 210 DR-----------IARVAFETARKRRGKLCSVDKANVLE-ASILWRKRVTAL-ASEYPD- 255 + AR FE + ++ K + + ++ + A EY + Sbjct: 176 VQGIHNTVASIGHFARACFEYSLDQKIDCWFATKDTISKQYDQRFKIIFEEIFAQEYKEK 235 Query: 256 -----VELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLS 310 +E + +D+ ++++ N GD++SD + GS+ M+ S +S Sbjct: 236 FAAAGIEYFYTLIDDVVARMMKTEGGM-LWACKNYDGDVMSDMVASAFGSLAMMSSVLVS 294 Query: 311 DSGPGLFEPIHGSA-----PDIAGQDKA-NPLATILSAAMLLKYGLGEEK-------AAK 357 G +E HG+ + G+ + NP+A I + L+ GE Sbjct: 295 PYGYFEYEAAHGTVQRHYYQHLKGERTSTNPVALIYAWTGALRKR-GELDGTPDLCAFCD 353 Query: 358 RIEDAVLVALNNGFRTGDIYS----AGTKLVGCKEMGEEVLKSVD 398 +E + + +G+ TGD+ A K++ E +E+ K + Sbjct: 354 SLEAITIECIESGYMTGDLARICEPAAIKVLDSIEFIDELGKRLQ 398 >6BL1-B nrPDB Length = 425 Score = 116 bits (291), Expect = 2e-26, Method: Composition-based stats. Identities = 67/400 (16%), Positives = 139/400 (34%), Gaps = 51/400 (12%) Query: 54 GPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGA 113 G E+ I ++++ VE + +G D + ++ A K+ + + A Sbjct: 15 GDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCA 74 Query: 114 IGGY---KWDNNEKHLRPEKGLLQIRAALK--VFANLRPATVLPQLVDASTLK------- 161 + + + + IR L VF +P+LV Sbjct: 75 TITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHA 134 Query: 162 -REVAEGVDLMV-----VRELTGGIYFGEPRG-IKTNENGEEVGFNTEVYAAHE-IDRIA 213 + D +V V E+T G + + E G +Y + I+ A Sbjct: 135 YGDQYRATDFVVPGPGKV-EITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFA 193 Query: 214 RVAFETARKRRGKLCSVDKANVLE-ASILWRKRVTAL-ASEYPD------VELSHMYVDN 265 +F+ A + L K +L+ ++ + +Y + H +D+ Sbjct: 194 HSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDD 253 Query: 266 AAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLF-EPIHGSA 324 Q ++ F N GD+ SD + GS+GM+ S + G + E HG+ Sbjct: 254 MVAQAMKSEGGF-IWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTV 312 Query: 325 PDI-----AGQDKA-NPLATILSAAMLLKYGLGEEK------AAKRIEDAVLVALNNGFR 372 GQ+ + NP+A+I + L + + A +E+ + + GF Sbjct: 313 TRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFM 372 Query: 373 TGDIYS--------AGTKLVGCKEMGEEVLKSVDSQVPAS 404 T D+ + + + E +++ +++ ++ + Sbjct: 373 TKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 412 >5I96-A nrPDB Length = 458 Score = 115 bits (287), Expect = 4e-26, Method: Composition-based stats. Identities = 50/298 (16%), Positives = 101/298 (33%), Gaps = 46/298 (15%) Query: 148 ATVLPQLVDASTLK--------REVAEGVDLMVVRELTGGIYF------GEPRGIKTNEN 193 +P+LV T + + D + R T + F G N Sbjct: 154 CKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP 213 Query: 194 GEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEA-SILWRKRVTAL-AS 251 VG I A F+ A +++ L K +L+A ++ + Sbjct: 214 AGGVGMG-MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDK 272 Query: 252 EYP------DVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLP 305 Y + H +D+ Q+++ F N GD+ SD + GS+G++ Sbjct: 273 HYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMT 331 Query: 306 SASLSDSGPGLF-EPIHGSA-----PDIAGQDKA-NPLATILSAAMLLKYGLGEE----- 353 S + G + E HG+ G+ + NP+A+I + L++ + Sbjct: 332 SVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDL 391 Query: 354 -KAAKRIEDAVLVALNNGFRTGDIYS---------AGTKLVGCKEMGEEVLKSVDSQV 401 + A+ +E + + +G T D+ + + + + ++D + Sbjct: 392 IRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 449 >4HCX-A nrPDB Length = 409 Score = 114 bits (285), Expect = 8e-26, Method: Composition-based stats. Identities = 37/221 (16%), Positives = 84/221 (38%), Gaps = 25/221 (11%) Query: 206 AHEIDRIARVAFETARKRRGKLCSVDKANVLEA-SILWRKRVTALASE-------YPDVE 257 I AR +F + + K +L+A +++ + E + Sbjct: 189 KESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAGLT 248 Query: 258 LSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLF 317 H +D+ ++ + N GD+ SD + GS+G++ S ++ G + Sbjct: 249 YEHRLIDDMVAACLKWEGGY-VWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVE 307 Query: 318 -EPIHGSAPDI-----AGQDKA-NPLATILSAAMLLKYGLGEE------KAAKRIEDAVL 364 E HG+ AG+ + NP+A+I + L++ + A ++E V+ Sbjct: 308 AEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVI 367 Query: 365 VALNNGFRTGDIY---SAGTKLVGCKEMGEEVLKSVDSQVP 402 + +G T D+ + +E + + +++ ++ Sbjct: 368 ATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 >3US8-A nrPDB Length = 427 Score = 112 bits (279), Expect = 4e-25, Method: Composition-based stats. Identities = 62/414 (14%), Positives = 139/414 (33%), Gaps = 74/414 (17%) Query: 46 TLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKE 105 ++ DG E+ I ++ ++ + +G D + + +A K+ Sbjct: 32 PVVELDG--DEMTRIIWQFIKDKLIHPYLDLDLEYYDLGVENRDATDDQVTIDAANAIKK 89 Query: 106 SDAVLL--------GAIGGYK----WDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQ 153 + G + +K W + +R G + R + +P+ Sbjct: 90 HGVGVKCATITPDEGRVEEFKLKKMWKSPNGTIRNILGGVIFREPI-------ICKNVPR 142 Query: 154 LVDASTLKREVAEGVDLMVVRELTGGIY-----------------FGEPRGIKTNE--NG 194 LV T ++V R G Y GE ++ + Sbjct: 143 LVPGWTKP--------IIVGRHAFGDQYRATDFKFPGKGKLSIKFVGEDGQTIEHDVYDA 194 Query: 195 EEVGFNTEVYA-AHEIDRIARVAFETARKRRGKLCSVDKANVLEA-SILWRKRV-----T 247 G +Y I AR +F +R+ + K +L+A ++ Sbjct: 195 PGAGVALAMYNLDESITEFARASFNYGLQRKVPVYLSTKNTILKAYDGRFKDIFQKVFDE 254 Query: 248 ALASEYP--DVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLP 305 A+++ + H +D+ ++ + N GD+ SD + GS+G++ Sbjct: 255 EFAAQFKAEKLWYEHRLIDDMVASALKWSGGY-VWACKNYDGDVQSDIVAQGFGSLGLMT 313 Query: 306 SASLSDSGPGLF-EPIHGSA-----PDIAGQDKA-NPLATILSAAMLLKYGLGEE----- 353 S ++ G + E HG+ G++ + N +A+I + L + + Sbjct: 314 SVLMTPDGKTVEAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDGNAEL 373 Query: 354 -KAAKRIEDAVLVALNNGFRTGDIY---SAGTKLVGCKEMGEEVLKSVDSQVPA 403 K ++ +E + + +GF T D+ + +++ +++ + A Sbjct: 374 AKFSETLERVCVDTVESGFMTKDLALLIGPDQPWLSTTGFLDKIDENLRKAMAA 427 >2QFY-A nrPDB Length = 427 Score = 108 bits (271), Expect = 3e-24, Method: Composition-based stats. Identities = 65/418 (15%), Positives = 142/418 (33%), Gaps = 62/418 (14%) Query: 39 GKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEE 98 K + ++ DG E+ I + +++ L ++ + + + + D + ++ Sbjct: 17 SKIKVKQPVVELDG--DEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSDKITQD 74 Query: 99 TISAAKESDAVLLGAIGGY---KWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLV 155 A K+ + A + H + IR L R V+P++ Sbjct: 75 AAEAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTV-FREPIVIPRIP 133 Query: 156 DASTLKREVAEGVDLMVVRELTGGIYF----------GEPRGIKTNENGEEVGFNTEVY- 204 + +++ R G Y K ++ +VY Sbjct: 134 RLVPRWEKP-----IIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYD 188 Query: 205 ------------AAHEIDRIARVAFETARKRRGKLCSVDKANVLE-ASILWRKRVTAL-A 250 I+ A +F+ A ++ L K +L+ ++ + Sbjct: 189 YKGSGVAMAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYE 248 Query: 251 SEYP------DVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGML 304 ++Y + H +D+ Q+++ F + N GD+ SD + GS+G++ Sbjct: 249 AQYKSKFEQLGIHYEHRLIDDMVAQMIKSKGGF-IMALKNYDGDVQSDIVAQGFGSLGLM 307 Query: 305 PSASLSDSGPGLF-EPIHGSA-----PDIAGQDKA-NPLATILSAA------MLLKYGLG 351 S ++ G E HG+ G++ + N +A+I + + L Sbjct: 308 TSILVTPDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPA 367 Query: 352 EEKAAKRIEDAVLVAL-NNGFRTGDIY-----SAGTKLVGCKEMGEEVLKSVDSQVPA 403 K A +E A L + +G T D+ + + V +E + V K + ++ + Sbjct: 368 LCKFANILESATLNTVQQDGIMTKDLALACGNNERSAYVTTEEFLDAVEKRLQKEIKS 425 >6DUE-A nrPDB Length = 787 Score = 36.2 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 17/101 (16%) Query: 221 RKRRGKLCSV-DKANVLEASILWRKRVTALASEYPDVELSHMYVDN-------AAMQLVR 272 +KR + +V NV + +W ++ E PD+ + V +Q+ Sbjct: 17 KKRSSDVHAVDHSGNVYKGFQIWTDLAPSVKEE-PDLMFAKCIVQAGTDKGNLTCVQI-- 73 Query: 273 DPKQFD----TIVTNNIFGDILSDEASMITGSIGMLPSASL 309 DP FD N + L D M G IGMLP ++ Sbjct: 74 DPPGFDEPFEVPQANAWNVNSLID--PMTYGDIGMLPHTNI 112 >4JQP-A nrPDB Length = 342 Score = 33.1 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 26/66 (39%), Gaps = 7/66 (10%) Query: 275 KQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPI-HGSAPDIAGQDKA 333 FD +V D+ +G+ +++ + + HG+A DIAG+ Sbjct: 270 GDFDLVVAM------YHDQGHGPVKVLGLEAGVNVTVGLEVIRTSVDHGTAFDIAGKGVV 323 Query: 334 NPLATI 339 + + + Sbjct: 324 DEGSML 329 >3ABT-A nrPDB Length = 662 Score = 32.3 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 43/128 (33%), Gaps = 15/128 (11%) Query: 287 GDILSDEASMITGSIGMLPSASLS----------DSGPGLFEPIHGSAPDIAGQDKANPL 336 G+ ++D +M+ +G P A +S L+E + P + Sbjct: 152 GNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEF 211 Query: 337 ATILSAAMLLKYGLG---EEKAAKRIEDAVLVALN-NGFRTGDIYSAG-TKLVGCKEMGE 391 +L A L + L + A+ V + D K+V +E + Sbjct: 212 NRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELK 271 Query: 392 EVLKSVDS 399 E+L + + Sbjct: 272 ELLNKMVN 279 >1EAR-A nrPDB Length = 147 Score = 32.3 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 40/104 (38%), Gaps = 11/104 (10%) Query: 160 LKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTE-----VYAAHEIDRIAR 214 L++E G D+ + E +G + +G+ + + + T+ V + + + Sbjct: 35 LRKETENGTDIAIKLENSGTLRYGD---VLYESDDTLIAIRTKLEKVYVIKPQTMQEMGK 91 Query: 215 VAFETARKRRGKLCSVDKANVL-EASILWRKRVTALASEYPDVE 257 +AFE R +C ++ +L K + + Y E Sbjct: 92 MAFEI--GNRHTMCIIEDDEILVRYDKTLEKLIDEVGVSYEQSE 133 >5L3D-A nrPDB Length = 852 Score = 31.9 bits (71), Expect = 0.54, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 43/128 (33%), Gaps = 15/128 (11%) Query: 287 GDILSDEASMITGSIGMLPSASLS----------DSGPGLFEPIHGSAPDIAGQDKANPL 336 G+ ++D +M+ +G P A +S L+E + P + Sbjct: 323 GNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEF 382 Query: 337 ATILSAAMLLKYGLG---EEKAAKRIEDAVLVALN-NGFRTGDIYSAG-TKLVGCKEMGE 391 +L A L + L + A+ V + D K+V +E + Sbjct: 383 NRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELK 442 Query: 392 EVLKSVDS 399 E+L + + Sbjct: 443 ELLNKMVN 450 >1IY9-A nrPDB Length = 275 Score = 30.0 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 26/58 (44%), Gaps = 5/58 (8%) Query: 225 GKLCSVD-KANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIV 281 K VD V+E S + ++A + D + + VD+ M + + Q+D I+ Sbjct: 100 KKATLVDIDGKVIEYSKKFL---PSIAGKLDDPRV-DVQVDDGFMHIAKSENQYDVIM 153 >3R4T-A nrPDB Length = 467 Score = 30.0 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 26/83 (31%), Gaps = 1/83 (1%) Query: 182 FGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASIL 241 GE R + N E V + +V A + A VAF+ A R L A + Sbjct: 137 SGEKRTVLFNSGAEAVENSIKV-ARAHTRKQAVVAFDYAYHGRTNLTMALTAKSMPYKSG 195 Query: 242 WRKRVTALASEYPDVELSHMYVD 264 + + +D Sbjct: 196 FGPFAPEIYRAPVSYPYRDNLLD 218 >5ZQM-A nrPDB Length = 309 Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%) Query: 128 PEKGLLQIRAALK--VFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFG 183 P +R L+ ++ L A +L+ S + E+A+ VDL + E G Y G Sbjct: 182 PWDIDEALRRRLEKRIYIPLPSAKGREELLRISLRELELADDVDLASIAENMEG-YSG 238 >3RHD-A nrPDB Length = 486 Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 60/373 (16%), Positives = 118/373 (31%), Gaps = 56/373 (15%) Query: 13 KVPATFRAVSKQSLAPFRVRCAVAS--PGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGS 70 K+PA R +K+++ V P KRY I + I E +L + Sbjct: 27 KIPALSREEAKEAIDTAEKYKEVMKNLPITKRYNILMNIAKQI-KEKKEELAKIL-AIDA 84 Query: 71 LEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEK 130 + ++ E+ L + E D ++ + + Sbjct: 85 GKPIKQARVEVERSIGTFKLAAFYVKEHRDEVIPSDDRLIF---------TRREPVGIVG 135 Query: 131 GLLQIRAALKVFAN-LRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIK 189 + L + A+ + PA ++ + ++L + E Y P G+ Sbjct: 136 AITPFNFPLNLSAHKIAPAIATGNVIVHHPSSKAPLVCIELAKIIENALKKY-NVPLGVY 194 Query: 190 TNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTAL 249 G E+ +++ I +F + K + KA ++K L Sbjct: 195 NLLTGAGEVVGDEIVVNEKVNMI---SFTGSSKVGELITK--KAG-------FKKIALEL 242 Query: 250 ASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASL 309 P++ L ++ A L++ + V ++ G IL DE S+ Sbjct: 243 GGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISV-GMILVDE--------------SI 287 Query: 310 SDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNN 369 +D +F + NPL L+ + A+ +E V A++ Sbjct: 288 ADKFIEMF------VNKAKVLNVGNPLDEKTDVGPLIS-----VEHAEWVEKVVEKAIDE 336 Query: 370 GFRTGDIYSAGTK 382 G G + G + Sbjct: 337 G---GKLLLGGKR 346 >1VGT-A nrPDB Length = 238 Score = 29.6 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 24/50 (48%), Gaps = 1/50 (2%) Query: 2 AAALQTNIRTVKVPATFRAVSKQSLAPFRVRCAVASPGKKRYTITLLPGD 51 AA ++T + P + ++ Q++ V +A P KR I + PGD Sbjct: 16 AAGFGRRMQT-ECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGD 64 >6AJJ-A nrPDB Length = 943 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 27/66 (40%), Gaps = 10/66 (15%) Query: 285 IFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAM 344 +FG +++ I G + + + + F P+H A P+ T++ + Sbjct: 217 VFGTVIAAALPAIIGGLAIAGALGIMR-LVAEFTPVH---------FFAQPVVTLIGLGI 266 Query: 345 LLKYGL 350 + YGL Sbjct: 267 AIDYGL 272 >2HI1-A nrPDB Length = 330 Score = 28.9 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 16/29 (55%), Gaps = 2/29 (6%) Query: 37 SPGKKRYTITLLPGD--GIGPEVVSIAKN 63 S + T+ + GD GIGPE++ A + Sbjct: 1 SNAMETKTVAITMGDPAGIGPEIIVKALS 29 >5ZBN-A nrPDB Length = 371 Score = 28.5 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 19/47 (40%), Gaps = 3/47 (6%) Query: 233 ANVLEASILWRKRVTALASEYPDVELSHMYV---DNAAMQLVRDPKQ 276 ++ S V +AS P + +YV N QLVR ++ Sbjct: 101 GTIMTLSSWATSSVEEVASTGPGIRFFQLYVYKDRNVVAQLVRRAER 147 >1AL8-A nrPDB Length = 359 Score = 28.5 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 19/47 (40%), Gaps = 3/47 (6%) Query: 233 ANVLEASILWRKRVTALASEYPDVELSHMYV---DNAAMQLVRDPKQ 276 ++ S V +AS P + +YV N QLVR ++ Sbjct: 100 GTIMTLSSWATSSVEEVASTGPGIRFFQLYVYKDRNVVAQLVRRAER 146 >2CDH-0 nrPDB Length = 226 Score = 27.7 bits (60), Expect = 8.3, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 19/47 (40%), Gaps = 3/47 (6%) Query: 233 ANVLEASILWRKRVTALASEYPDVELSHMYV---DNAAMQLVRDPKQ 276 ++ S V +AS P + +YV N QLVR ++ Sbjct: 40 GTIMTLSSWATSSVEEVASTGPGIRFFQLYVYKDRNVVAQLVRRAER 86 >3O3U-N nrPDB Length = 581 Score = 27.7 bits (60), Expect = 8.7, Method: Composition-based stats. Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 10/92 (10%) Query: 20 AVSKQSLAPFRVRCAVASPGKK---RYTITL--LPGDGIGPEVVSIAKNVLQQAGSLEGV 74 AV Q FR + A+ GK+ Y + + +PG PE+V A + + G Sbjct: 438 AVGIQDEGIFRCQ-AMNRNGKETKSNYRVRVYQIPGK---PEIVDSASELTAGVPNKVGT 493 Query: 75 EFNFREMPIGGAALDLVGVPL-PEETISAAKE 105 + P G + L G PL P E + KE Sbjct: 494 CVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKE 525 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.135 0.367 Lambda K H 0.267 0.0416 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,073,540 Number of Sequences: 36641 Number of extensions: 608448 Number of successful extensions: 2356 Number of sequences better than 10.0: 63 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 1957 Number of HSP's gapped (non-prelim): 125 length of query: 405 length of database: 10,336,785 effective HSP length: 99 effective length of query: 306 effective length of database: 6,709,326 effective search space: 2053053756 effective search space used: 2053053756 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)