BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P93031 (373 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1N7G-A nrPDB 780 0.0 1DB3-A nrPDB 401 e-112 6GPK-A nrPDB 396 e-111 5UZH-A nrPDB 394 e-110 2Z95-A nrPDB 353 9e-98 1RPN-A nrPDB 325 2e-89 2PK3-A nrPDB 135 4e-32 1KEU-A nrPDB 79 3e-15 2HUN-A nrPDB 79 4e-15 1OC2-A nrPDB 74 7e-14 1BXK-A nrPDB 73 2e-13 6BI4-A nrPDB 68 6e-12 1ORR-A nrPDB 68 6e-12 1R66-A nrPDB 60 1e-09 2PZM-A nrPDB 60 1e-09 3RUE-A nrPDB 57 1e-08 2Q1W-A nrPDB 54 8e-08 1WVG-A nrPDB 52 5e-07 2C20-A nrPDB 47 1e-05 1GY8-A nrPDB 45 4e-05 4LIS-A nrPDB 45 7e-05 1RKX-A nrPDB 42 4e-04 1Z45-A nrPDB 41 0.001 4R1T-A nrPDB 36 0.023 1ZZE-A nrPDB 33 0.19 2NNL-D nrPDB 32 0.30 4WOK-A nrPDB 32 0.31 2P4H-X nrPDB 32 0.50 4R1U-A nrPDB 30 1.2 3ENK-A nrPDB 30 1.3 4QUK-A nrPDB 30 1.6 5Z6T-A nrPDB 30 2.1 2V6G-A nrPDB 30 2.3 6G4Q-B nrPDB 29 2.8 5ZCM-A nrPDB 29 3.1 1K8C-A nrPDB 29 3.2 3SXP-A nrPDB 29 4.1 3U9L-A nrPDB 29 4.2 5U9C-A nrPDB 28 4.5 6CE1-A nrPDB 28 5.0 5EX8-A nrPDB 28 7.3 >1N7G-A nrPDB Length = 381 Score = 780 bits (2013), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/373 (100%), Positives = 373/373 (100%) Query: 1 MASENNGSRSDSESITAPKADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIR 60 MASENNGSRSDSESITAPKADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIR Sbjct: 1 MASENNGSRSDSESITAPKADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIR 60 Query: 61 RSSNFNTQRINHIYIDPHNVNKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVA 120 RSSNFNTQRINHIYIDPHNVNKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVA Sbjct: 61 RSSNFNTQRINHIYIDPHNVNKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVA 120 Query: 121 VSFEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH 180 VSFEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH Sbjct: 121 VSFEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH 180 Query: 181 PRSPYAASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL 240 PRSPYAASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL Sbjct: 181 PRSPYAASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL 240 Query: 241 QTKLFLGNLQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGL 300 QTKLFLGNLQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGL Sbjct: 241 QTKLFLGNLQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGL 300 Query: 301 NWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKV 360 NWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKV Sbjct: 301 NWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKV 360 Query: 361 LVDAGYMDAKQQP 373 LVDAGYMDAKQQP Sbjct: 361 LVDAGYMDAKQQP 373 >1DB3-A nrPDB Length = 372 Score = 401 bits (1030), Expect = e-112, Method: Compositional matrix adjust. Identities = 195/366 (53%), Positives = 255/366 (69%), Gaps = 31/366 (8%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+ALITG+TGQDGSYL EFLL KGYEVHG+ RR+S+FNT+R++HIY DPH N LH Sbjct: 2 KVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKF-HLH 60 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 Y DL+D S+L R + ++PDEVYNL A SHVAVSFE P+YTADV A G LRLLEA+R Sbjct: 61 YGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAIRFLG 120 Query: 149 IDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 ++ + ++YQA +SE++G PQ ETTPF+PRSPYA +K A+W TVNYRE+YG++A Sbjct: 121 LE--KKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKLYAYWITVNYRESYGMYA 178 Query: 208 CNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL 267 CNGILFNHESPRRGE FVTRKITRA+ I GL++ L+LGN+ + RDWG A DYV+ W+ Sbjct: 179 CNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKMQWM 238 Query: 268 MLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWK------------------------ 303 MLQQE+P+D+V+AT ++V +F++++ LG+ + Sbjct: 239 MLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAPGVK 298 Query: 304 ---DYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKV 360 + +D RYFRPAEV+ L GD +KA E LGWKP++ ++V MV DLE AK+ + Sbjct: 299 PGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMVANDLEAAKKHSL 358 Query: 361 LVDAGY 366 L GY Sbjct: 359 LKSHGY 364 >6GPK-A nrPDB Length = 373 Score = 396 bits (1018), Expect = e-111, Method: Compositional matrix adjust. Identities = 193/347 (55%), Positives = 253/347 (72%), Gaps = 20/347 (5%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 R +ALITGITGQDGSYL EFLL KGYEVHG++RRSS+FNT RI H+Y +P + MKL Sbjct: 24 RNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKL 83 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 HY DLTD++ L + I+ +KP E+YNL AQSHV +SF++ +YTADV G LRLL+AV++ Sbjct: 84 HYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTC 143 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLF 206 + + +VK+YQA +S+++G PQ ETTPF+PRSPY A+K A+W VN+REAY LF Sbjct: 144 GLIN--SVKFYQASTSQLYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLF 201 Query: 207 ACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMW 266 A NGILFNHESPRRG NFVTRKI+R++ +I +G LGNL A RDWG A DYVEAMW Sbjct: 202 AVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMW 261 Query: 267 LMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLG--LNW---------------KDYVEID 309 LMLQ ++P+D+V+AT E H+V EF++ SF ++G + W K +V +D Sbjct: 262 LMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWEGKNENEVGRCKETGKVHVTVD 321 Query: 310 QRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAK 356 +Y+RP EVD LQGD +KAK+ L WKP+V F++LV+ MV D+EL + Sbjct: 322 LKYYRPTEVDFLQGDCTKAKQKLNWKPRVAFDELVREMVHADVELMR 368 >5UZH-A nrPDB Length = 345 Score = 394 bits (1011), Expect = e-110, Method: Compositional matrix adjust. Identities = 203/346 (58%), Positives = 249/346 (71%), Gaps = 21/346 (6%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+ALITGITGQDGSYL EFLL KGY V+G+IRRSS+FNT R+ H+Y D H + KA KL Sbjct: 2 KVALITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIH-ITKAKFKLL 60 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 Y DLTD +L I IKPDE+YNLAAQSHV VSFE+P+YTA+V G LRLLEA+R+ Sbjct: 61 YGDLTDTGNLISIIAKIKPDEIYNLAAQSHVKVSFEMPEYTANVDGIGTLRLLEAIRACG 120 Query: 149 IDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 ++ + K+YQA +SE++G PQ ETTPF+PRSPYA +K ++W VNYREAY +FA Sbjct: 121 LE--KKTKFYQASTSELYGLVQEVPQKETTPFYPRSPYACAKLYSYWIVVNYREAYNMFA 178 Query: 208 CNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL 267 NGILFNHES RRG FVTRKIT A+ RIK+GLQ L+LGNL A RDWG A DYVEAMWL Sbjct: 179 LNGILFNHESIRRGPTFVTRKITMAVARIKLGLQDCLYLGNLDAERDWGHAKDYVEAMWL 238 Query: 268 MLQQEKPDDYVVATEEGHTVEEFLDVSFGYLG--LNWKD---------------YVEIDQ 310 MLQQE+P D+ VAT E H+V EF++ +F +G + WK V +D Sbjct: 239 MLQQEQPRDFCVATGEKHSVREFVEKAFACIGQTVEWKGERGTVEEHGVVDGVVRVRVDP 298 Query: 311 RYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAK 356 RYFRP EVD L GD + A+ VLGWK +V FE+LV+ MV+ D+EL + Sbjct: 299 RYFRPTEVDQLLGDPTLAETVLGWKRKVSFEELVRGMVEGDIELLQ 344 >2Z95-A nrPDB Length = 345 Score = 353 bits (905), Expect = 9e-98, Method: Compositional matrix adjust. Identities = 187/352 (53%), Positives = 240/352 (68%), Gaps = 28/352 (7%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K ALITGI GQDG+YL + LL KGYEV+G RRS F + R+ + I+ +K+ Sbjct: 4 KRALITGIRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIEND------VKII 57 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 + DL + S++ R I+ ++PDEVYNLAAQS V VSFE P TA+V A G LR+LEA+R+ Sbjct: 58 HMDLLEFSNIIRTIEKVQPDEVYNLAAQSFVGVSFEQPILTAEVDAIGVLRILEALRTVK 117 Query: 149 IDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 D+ K+YQA +SEMFG PQ+E TPF+PRSPYA +K HW TVNYREAY +FA Sbjct: 118 PDT----KFYQASTSEMFGKVQEIPQTEKTPFYPRSPYAVAKLFGHWITVNYREAYNMFA 173 Query: 208 CNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL 267 C+GILFNHESP RG FVTRKIT +L RIK GLQ KL LGNL A RDWG+A +YVEAMWL Sbjct: 174 CSGILFNHESPLRGIEFVTRKITYSLARIKYGLQDKLVLGNLNAKRDWGYAPEYVEAMWL 233 Query: 268 MLQQEKPDDYVVATEEGHTVEEFL---------DVSFGYLGLNWKD--------YVEIDQ 310 M+QQ +PDDYV+AT E HTV EF+ D+ + G+N K VE+ + Sbjct: 234 MMQQPEPDDYVIATGETHTVREFVEKAAKIAGFDIEWVGEGINEKGIDRNTGKVIVEVSE 293 Query: 311 RYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLV 362 +FRPAEVD L G+ KA + LGWKP+ F++LV++M++ DL+ + +V V Sbjct: 294 EFFRPAEVDILVGNPEKAMKKLGWKPRTTFDELVEIMMEADLKRVRDREVSV 345 >1RPN-A nrPDB Length = 335 Score = 325 bits (832), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 169/329 (51%), Positives = 224/329 (68%), Gaps = 11/329 (3%) Query: 31 ALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYA 90 AL+TGITGQDG+YL + LL KGY VHGL+ R S+ R+ + I+ ++ Sbjct: 17 ALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGD------IQYEDG 70 Query: 91 DLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTID 150 D+ DA S++R + +P EVYNLAAQS V S+ P T V G LLEA+R + + Sbjct: 71 DMADACSVQRAVIKAQPQEVYNLAAQSFVGASWNQPVTTGVVDGLGVTHLLEAIRQFSPE 130 Query: 151 SGRTVKYYQAGSSEMFGSTPPP-QSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFACN 209 + ++YQA +SEMFG Q E TPF+PRSPY +K HW TVNYRE++GL A + Sbjct: 131 T----RFYQASTSEMFGLIQAERQDENTPFYPRSPYGVAKLYGHWITVNYRESFGLHASS 186 Query: 210 GILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWLML 269 GILFNHESP RG FVTRK+T A+ RIK+G Q +L LGN+ A RDWGFAGDYVEAMWLML Sbjct: 187 GILFNHESPLRGIEFVTRKVTDAVARIKLGKQQELRLGNVDAKRDWGFAGDYVEAMWLML 246 Query: 270 QQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDASKAK 329 QQ+K DDYVVAT TV + ++F ++GL+++D+++ID +FRPAEVD L G+ +KA+ Sbjct: 247 QQDKADDYVVATGVTTTVRDMCQIAFEHVGLDYRDFLKIDPAFFRPAEVDVLLGNPAKAQ 306 Query: 330 EVLGWKPQVGFEKLVKMMVDEDLELAKRE 358 VLGWKP+ ++L++MMV+ DL RE Sbjct: 307 RVLGWKPRTSLDELIRMMVEADLRRVSRE 335 >2PK3-A nrPDB Length = 321 Score = 135 bits (339), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 102/317 (32%), Positives = 150/317 (47%), Gaps = 27/317 (8%) Query: 31 ALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYA 90 ALITG+ G G YL L + EV F T R N + N ++ L Sbjct: 15 ALITGVAGFVGKYLANHLTEQNVEV---------FGTSRNNEAKLP----NVEMISL--- 58 Query: 91 DLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTID 150 D+ D+ +++ I IKPD +++LAA+S V S+ T G L +L+AVR +D Sbjct: 59 DIMDSQRVKKVISDIKPDYIFHLAAKSSVKDSWLNKKGTFSTNVFGTLHVLDAVRDSNLD 118 Query: 151 SGRTVKYYQAGSSEMFGSTPP---PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 + GSSE +G P P SE P SPY SK + Y +AYG+ Sbjct: 119 C----RILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAYGMDI 174 Query: 208 CNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLF-LGNLQASRDWGFAGDYVEAMW 266 + FNH P + FVT+ + + I++ Q + +GNL+A RD+ D V+A W Sbjct: 175 IHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDFTDVRDIVQAYW 234 Query: 267 LMLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDA 325 L+ Q K D Y V + G +++ LD+ N K E++ RP+EV L G Sbjct: 235 LLSQYGKTGDVYNVCSGIGTRIQDVLDLLLAM--ANVKIDTELNPLQLRPSEVPTLIGSN 292 Query: 326 SKAKEVLGWKPQVGFEK 342 + K+ GWKP++ EK Sbjct: 293 KRLKDSTGWKPRIPLEK 309 >1KEU-A nrPDB Length = 361 Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 77/287 (26%), Positives = 118/287 (41%), Gaps = 32/287 (11%) Query: 87 LHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRS 146 +AD+ D++ + R + +PD V +LAA+SHV S P + G LLE R Sbjct: 54 FEHADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVARK 113 Query: 147 HTI----DSGRTVKYYQAGSSEMFGSTPPPQ-----------SETTPFHPRSPYAASKCA 191 + D +++ + E++G P P +ETT + P SPY+ASK + Sbjct: 114 YWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKAS 173 Query: 192 AHWYTVNYREAYGLFACNGILFNHESPRR-GENFVTRKITRALGRIKVGLQTKLFLGNLQ 250 + +R YGL N+ P E + I AL G ++ G Sbjct: 174 SDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALE----GKPLPIY-GKGD 228 Query: 251 ASRDWGFAGDYVEAMWLMLQQEKP-DDYVVATEEGHTVEEFLDVSFGYLGL------NWK 303 RDW + D+ A+ +++ + K + Y + GH ++ LDV F L Sbjct: 229 QIRDWLYVEDHARALHMVVTEGKAGETYNIG---GHNEKKNLDVVFTICDLLDEIVPKAT 285 Query: 304 DYVE-IDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVD 349 Y E I RP DA K LGWKP FE ++ V+ Sbjct: 286 SYREQITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVE 332 >2HUN-A nrPDB Length = 336 Score = 78.6 bits (192), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 86/336 (25%), Positives = 146/336 (43%), Gaps = 23/336 (6%) Query: 32 LITGITGQDGSYLTEFLLGK--GYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 L+TG G GS ++L K +EV + + N + + DP +K Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPR---YTFVKGDV 63 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 AD L R K D V +LAA+SHV S P+ G LLE++R Sbjct: 64 ADYELVKELVR-----KVDGVVHLAAESHVDRSISSPEIFLHSNVIGTYTLLESIRRENP 118 Query: 150 DSGRTVKYYQAGSSEMFGSTPPPQ-SETTPFHPRSPYAASKCAAHWYTVNYREAYGLFAC 208 + V++ + E++G +E P SPY+A+K A+ + + Y L A Sbjct: 119 E----VRFVHVSTDEVYGDILKGSFTENDRLMPSSPYSATKAASDMLVLGWTRTYNLNAS 174 Query: 209 NGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL- 267 N+ P + F + I + + R +GL+ ++ G + RDW + D+V A+ L Sbjct: 175 ITRCTNNYGPYQ---FPEKLIPKTIIRASLGLKIPIY-GTGKNVRDWLYVEDHVRAIELV 230 Query: 268 MLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDASK 327 +L+ E + Y ++ E T E + + +G ++ +E+ + RP D+ K Sbjct: 231 LLKGESREIYNISAGEEKTNLEVVKIILRLMGKG-EELIELVED--RPGHDLRYSLDSWK 287 Query: 328 AKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLVD 363 L W+P+ F++ +K +D L+ K LVD Sbjct: 288 ITRDLKWRPKYTFDEGIKKTIDWYLKNEWWWKPLVD 323 >1OC2-A nrPDB Length = 348 Score = 74.3 bits (181), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 87/363 (23%), Positives = 150/363 (41%), Gaps = 42/363 (11%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K ++TG G GS ++ +VH + + + N I V +L Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRV-----ELV 59 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 D+ DA + + K D + + AA+SH S P G LLEA R + Sbjct: 60 VGDIADAELVDKL--AAKADAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKYD 117 Query: 149 IDSGRTVKYYQAGSSEMFGSTP-----PPQSE--------TTPFHPRSPYAASKCAAHWY 195 I +++ + E++G P P E T ++P SPY+++K A+ Sbjct: 118 I------RFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSPYSSTKAASDLI 171 Query: 196 TVNYREAYGLFACNGILFNHESP-RRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRD 254 + ++G+ A N+ P + E F+ R+IT L G++ KL+ G + RD Sbjct: 172 VKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILA----GIKPKLY-GEGKNVRD 226 Query: 255 WGFAGDYVEAMWLMLQQEK-PDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYF 313 W D+ +W +L + + + Y++ + +E L++ +G Y D Sbjct: 227 WIHTNDHSTGVWAILTKGRMGETYLIGADGEKNNKEVLELILEKMGQPKDAY---DHVTD 283 Query: 314 RPAEVDNLQGDASKAKEVLGWKPQV-----GFEKLVKMMVDEDLELAKREKVLVDAGYMD 368 R DASK ++ LGW PQ G E+ ++ D + + K EK V+A Y Sbjct: 284 RAGHDLRYAIDASKLRDELGWTPQFTDFSEGLEETIQWYTD-NQDWWKAEKEAVEANYAK 342 Query: 369 AKQ 371 ++ Sbjct: 343 TQE 345 >1BXK-A nrPDB Length = 355 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 92/343 (26%), Positives = 141/343 (41%), Gaps = 38/343 (11%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 RKI LITG G GS L +++ + + ++ + T N + + P Sbjct: 2 RKI-LITGGAGFIGSALVRYIINETSDAVVVVDKL----TYAGNLMSLAP-VAQSERFAF 55 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 D+ D + L R +PD V +LAA+SHV S + P + G LLEA R++ Sbjct: 56 EKVDICDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNIVGTYTLLEAARAY 115 Query: 148 ----TIDSGRTVKYYQAGSSEMFG---STPPPQSETTPFHPRSPYAASKCAAHWYTVNYR 200 T D +++ + E++G ST +ETTP+ P SPY+ASK ++ + Sbjct: 116 WNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAWL 175 Query: 201 EAYGLFACNGILFNHESPRR-GENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAG 259 YGL N+ P E + I AL G ++ GN Q RDW + Sbjct: 176 RTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALA----GKSLPVY-GNGQQIRDWLYVE 230 Query: 260 DYVEAMWLMLQQEK-PDDYVVATEEGHTVEEFLDVSFGYLGL-------------NWKDY 305 D+ A++ + K + Y + GH + LDV L +++D Sbjct: 231 DHARALYCVATTGKVGETYNIG---GHNERKNLDVVETICELLEELAPNKPHGVAHYRDL 287 Query: 306 VEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMV 348 + RP DASK LG PQ FE ++ V Sbjct: 288 ITFVAD--RPGHDLRYAIDASKIARELGCVPQETFESGMRKTV 328 >6BI4-A nrPDB Length = 346 Score = 68.2 bits (165), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 83/323 (25%), Positives = 137/323 (42%), Gaps = 37/323 (11%) Query: 32 LITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYAD 91 L+TG G GS ++L + YE + +I + + +N++ + N +K + Sbjct: 28 LVTGGAGFIGSNFVHYML-QSYETYKIINFDALTYSGNLNNVKSIQDHPNYYFVK---GE 83 Query: 92 LTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFE--IPDYTADVVATGALRLLEAVRSHTI 149 + + L I + N AA+SHV S E IP Y +V+ G + LLE V+ + Sbjct: 84 IQNGELLEHVIKERDVQVIVNFAAESHVDRSIENPIPFYDTNVI--GTVTLLELVKKYP- 140 Query: 150 DSGRTVKYYQAGSSEMFGSTPPPQ--SETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 +K Q + E++GS +E TP P SPY++SK +A + Y + Y L Sbjct: 141 ----HIKLVQVSTDEVYGSLGKTGRFTEETPLAPNSPYSSSKASADMIALAYYKTYQLPV 196 Query: 208 CNGILFNHESP-RRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMW 266 N+ P + E + +T AL K+ L G+ RDW D+ A+ Sbjct: 197 IVTRCSNNYGPYQYPEKLIPLMVTNALEGKKLPL-----YGDGLNVRDWLHVTDHCSAID 251 Query: 267 LMLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEI------DQRYFRPAEVD 319 ++L + + + Y + T E ++ LG KD + D+RY AE Sbjct: 252 VVLHKGRVGEVYNIGGNNEKTNVEVVEQIITLLGKTKKDIEYVTDRLGHDRRYAINAE-- 309 Query: 320 NLQGDASKAKEVLGWKPQVGFEK 342 K K W+P+ FE+ Sbjct: 310 -------KMKNEFDWEPKYTFEQ 325 >1ORR-A nrPDB Length = 347 Score = 68.2 bits (165), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 82/345 (23%), Positives = 127/345 (36%), Gaps = 42/345 (12%) Query: 32 LITGITGQDGSYLTEFLLGKGYEV---HGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 LITG G GS L F L +G ++ L R+ + N ++ + + Sbjct: 5 LITGGCGFLGSNLASFALSQGIDLIVFDNLSRKGATDNLHWLSSL---------GNFEFV 55 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 + D+ + + + R I PD ++LA Q + S + P ++ G L LLEAVR + Sbjct: 56 HGDIRNKNDVTRLITKYMPDSCFHLAGQVAMTTSIDNPCMDFEINVGGTLNLLEAVRQYN 115 Query: 149 IDSG-------------RTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWY 195 + KY + + P E+T SPY SK AA Y Sbjct: 116 SNCNIIYSSTNKVYGDLEQYKYNETETRYTCVDKPNGYDESTQLDFHSPYGCSKGAADQY 175 Query: 196 TVNYREAYGLFACNGILFNHESPRRGENFVTRK------ITRALGRIKVGLQTKLFL-GN 248 ++Y +GL N ++F H S G F T + IK G+ + GN Sbjct: 176 MLDYARIFGL---NTVVFRHSSMYGGRQFATYDQGWVGWFCQKAVEIKNGINKPFTISGN 232 Query: 249 LQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEI 308 + RD A D + + L G V + L +DY I Sbjct: 233 GKQVRDVLHAEDMISLYFTALANVSKIRGNAFNIGGTIVNSLSLLELFKLL---EDYCNI 289 Query: 309 DQRY----FRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVD 349 D R+ R ++ D K + W P+V + V+ M D Sbjct: 290 DMRFTNLPVRESDQRVFVADIKKITNAIDWSPKVSAKDGVQKMYD 334 >1R66-A nrPDB Length = 337 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 80/322 (24%), Positives = 127/322 (39%), Gaps = 38/322 (11%) Query: 32 LITGITGQDGSYLTEFLLGKGY------EVHGLIRRSSNFNTQRINHIYIDPHNVNKALM 85 L+TG G GS+ LL Y EV ++ S + R N + P + + L Sbjct: 4 LVTGGAGFIGSHFVRQLLAGAYPDVPADEV--IVLDSLTYAGNRAN---LAPVDADPRLR 58 Query: 86 KLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVR 145 +H D+ DA L R + + D + + AA+SHV S + G LL+ Sbjct: 59 FVH-GDIRDAGLLARELRGV--DAIVHFAAESHVDRSIAGASVFTETNVQGTQTLLQC-- 113 Query: 146 SHTIDSGRTVKYYQAGSSEMFGSTPPPQ-SETTPFHPRSPYAASKCAAHWYTVNYREAYG 204 +D+G + + E++GS +E++P P SPYAASK + Y YG Sbjct: 114 --AVDAG-VGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARAYHRTYG 170 Query: 205 L-----FACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAG 259 L CN N+ + E + +T L G L+ G+ R+W Sbjct: 171 LDVRITRCCN----NYGPYQHPEKLIPLFVTNLLD----GGTLPLY-GDGANVREWVHTD 221 Query: 260 DYVEAMWLMLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEV 318 D+ + L+L + + Y + T E + LG +W ++ R Sbjct: 222 DHCRGIALVLAGGRAGEIYHIGGGLELTNRELTGILLDSLGADWSSVRKVADRKGHDLRY 281 Query: 319 DNLQGDASKAKEVLGWKPQVGF 340 D K + LG++PQV F Sbjct: 282 SL---DGGKIERELGYRPQVSF 300 >2PZM-A nrPDB Length = 330 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 83/320 (25%), Positives = 135/320 (42%), Gaps = 44/320 (13%) Query: 32 LITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYAD 91 LITG G GS L E L +G+E+ + NF T + + P ++++ Sbjct: 24 LITGGAGCLGSNLIEHWLPQGHEILVI----DNFATGKREVL---PPVAGLSVIE---GS 73 Query: 92 LTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVAT---GALRLLEAVRSHT 148 +TDA L R D KP V H A +++ PD A+ AT G++ + +A Sbjct: 74 VTDAGLLERAFDSFKPTHVV------HSAAAYKDPDDWAEDAATNVQGSINVAKAASKAG 127 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPP-QSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 + R + + A + P P S T PF + Y SK A EA+ + + Sbjct: 128 VK--RLLNFQTALCYGRPATVPIPIDSPTAPF---TSYGISKTAG--------EAFLMMS 174 Query: 208 CNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL 267 ++ + G I R+K G K F + RD+ D++ L Sbjct: 175 DVPVVSLRLANVTGPRLAIGPIPTFYKRLKAG--QKCFCSD--TVRDFLDMSDFLAIADL 230 Query: 268 MLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPA--EVDNLQGD 324 LQ+ +P + V+T EGH+++E DV Y+G + V + P +V ++ D Sbjct: 231 SLQEGRPTGVFNVSTGEGHSIKEVFDVVLDYVGATLAEPVPV----VAPGADDVPSVVLD 286 Query: 325 ASKAKEVLGWKPQVGFEKLV 344 SK + GWK +V F+ + Sbjct: 287 PSKTETEFGWKAKVDFKDTI 306 >3RUE-A nrPDB Length = 351 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 81/325 (24%), Positives = 130/325 (40%), Gaps = 17/325 (5%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSS--NFNTQRINHIYIDPHNVNKALMK 86 K LITG+ G GS L E LL V GL S+ +N + + ++ Sbjct: 26 KTWLITGVAGFIGSNLLEKLLKLNQVVIGLDNFSTGHQYNLDEVKTLVSTEQWSRFCFIE 85 Query: 87 LHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRS 146 DLT + + +D V + AA V S P T TG L +L A ++ Sbjct: 86 GDIRDLTTCEQVMKGVD-----HVLHQAALGSVPRSIVDPITTNATNITGFLNILHAAKN 140 Query: 147 HTIDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGL 205 + S + A SS +G P P+ E +P SPYA +K Y Y YG Sbjct: 141 AQVQS-----FTYAASSSTYGDHPALPKVEENIGNPLSPYAVTKYVNEIYAQVYARTYGF 195 Query: 206 FACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAM 265 FN R+ N + + G+ + SRD+ + + ++ Sbjct: 196 KTIGLRYFNVFGRRQDPNGAYAAVIPKWTAAMLKGDDVYINGDGETSRDFCYIDNVIQMN 255 Query: 266 WL-MLQQEKPDD--YVVATEEGHTVEEFLDVSFGYLGL-NWKDYVEIDQRYFRPAEVDNL 321 L L ++ D Y VA + T+ E + L L + D + I R FR +V + Sbjct: 256 ILSALAKDSAKDNIYNVAVGDRTTLNELSGYIYDELNLIHHIDKLSIKYREFRSGDVRHS 315 Query: 322 QGDASKAKEVLGWKPQVGFEKLVKM 346 Q D +KA ++L ++P + + +++ Sbjct: 316 QADVTKAIDLLKYRPNIKIREGLRL 340 >2Q1W-A nrPDB Length = 333 Score = 54.3 bits (129), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 74/317 (23%), Positives = 124/317 (39%), Gaps = 53/317 (16%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K ITGI GQ GS++ E LL +G +V G+ NF T R H+ P+ + Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGI----DNFATGRREHLKDHPN------LTFV 71 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIP-DYTADVV--ATGALRLLEAVR 145 + D + + + I ++PD V H A S++ P D+ D + G +++A + Sbjct: 72 EGSIADHALVNQLIGDLQPDAVV------HTAASYKDPDDWYNDTLTNCVGGSNVVQAAK 125 Query: 146 SHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGL 205 + + GR V Y+Q + + P Q HPR+P +S + +Y E GL Sbjct: 126 KNNV--GRFV-YFQ---TALCYGVKPIQQPVRLDHPRNPANSSYAISKSANEDYLEYSGL 179 Query: 206 FACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNL---------QASRDWG 256 +FVT ++ +G V +F L +A RD+ Sbjct: 180 -----------------DFVTFRLANVVGPRNVSGPLPIFFQRLSEGKKCFVTKARRDFV 222 Query: 257 FAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPA 316 F D A + Y ++ ++E D + L Y E + R P Sbjct: 223 FVKDLARATVRAVDGVGHGAYHFSSGTDVAIKELYDAVVEAMAL--PSYPEPEIRELGPD 280 Query: 317 EVDNLQGDASKAKEVLG 333 + ++ D S+ + G Sbjct: 281 DAPSILLDPSRTIQDFG 297 >1WVG-A nrPDB Length = 359 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 40/121 (33%), Positives = 56/121 (46%), Gaps = 15/121 (12%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRS----SNFNTQRINHIYIDPHNVNKAL 84 K +TG TG GS+L+ +L G V G + S F R+N L Sbjct: 10 KRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIVRLND-----------L 58 Query: 85 MKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAV 144 M+ H D+ D LR I KP+ V+++AAQ V +S+E P T G + LLE V Sbjct: 59 MESHIGDIRDFEKLRSSIAEFKPEIVFHMAAQPLVRLSYEQPIKTYSTNVMGTVHLLETV 118 Query: 145 R 145 + Sbjct: 119 K 119 >2C20-A nrPDB Length = 330 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 70/276 (25%), Positives = 109/276 (39%), Gaps = 40/276 (14%) Query: 86 KLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVR 145 K + DL D + LR + V + AA S V VS E P + GAL LLE + Sbjct: 47 KFYNGDLRDKAFLRDVFTQENIEAVMHFAADSLVGVSMEKPLQYYNNNVYGALCLLEVMD 106 Query: 146 SHTIDSGRTVKYYQAGSSEMFGSTPPPQ-SETTPFHPRSPYAASKCAA----HWYTVNYR 200 +D K+ + ++ +G +E T +P + Y +K A HWY+ Sbjct: 107 EFKVD-----KFIFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQASN 161 Query: 201 EAYGLF--------ACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFL------ 246 Y +F NGI+ P T I L ++ +G + K+ + Sbjct: 162 LRYKIFRYFNVAGATPNGIIGEDHRPE------THLIPLVL-QVALGQREKIMMFGDDYN 214 Query: 247 -GNLQASRDWGFAGDYVEAMWLMLQQ----EKPDDYVVATEEGHTVEEFLDVSFGYLGLN 301 + RD+ D V A +L L+ + D Y + G +V+E +D N Sbjct: 215 TPDGTCIRDYIHVEDLVAAHFLGLKDLQNGGESDFYNLGNGNGFSVKEIVDAVREVT--N 272 Query: 302 WKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQ 337 + E+ R R + L + KAKE LGW P+ Sbjct: 273 HEIPAEVAPR--RAGDPARLVASSQKAKEKLGWDPR 306 >1GY8-A nrPDB Length = 397 Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 71/275 (25%), Positives = 105/275 (38%), Gaps = 54/275 (19%) Query: 108 DEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFG 167 D V ++ A V S P D G LRLL+A+ H D K + S+ +FG Sbjct: 95 DAVVHMCAFLAVGESVRDPLKYYDNNVVGILRLLQAMLLHKCD-----KIIFSSSAAIFG 149 Query: 168 --------STPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFACNGILFN----H 215 + P P SPY SK A + EAYG+ FN H Sbjct: 150 NPTMGSVSTNAEPIDINAKKSPESPYGESKLIAERMIRDCAEAYGIKGICLRYFNACGAH 209 Query: 216 ESPRRGENF--VTRKITRALGRI--KVGLQTKLFLGNLQAS------------------- 252 E GE++ T I LGR+ + +L + ++ Sbjct: 210 EDGDIGEHYQGSTHLIPIILGRVMSDIAPDQRLTIHEDASTDKRMPIFGTDYPTPDGTCV 269 Query: 253 RDWGFAGDYVEAMWLML---QQEKPDD-------YVVATEEGHTVEEFLDVSFGYLGLNW 302 RD+ D A L L ++ P+D + + T G++V E ++V+ G + Sbjct: 270 RDYVHVCDLASAHILALDYVEKLGPNDKSKYFSVFNLGTSRGYSVREVIEVARKTTG-HP 328 Query: 303 KDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQ 337 E +R PA L + KA+EVLGWKP+ Sbjct: 329 IPVRECGRREGDPAY---LVAASDKAREVLGWKPK 360 >4LIS-A nrPDB Length = 371 Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 97/386 (25%), Positives = 148/386 (38%), Gaps = 65/386 (16%) Query: 27 PRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMK 86 P L+TG TG GS+ T LL GY+V + N + + +N I + ++ + Sbjct: 2 PSGSVLVTGGTGYIGSFTTLALLEAGYKVV-VADNLYNSSAEALNRIEL----ISGKKAE 56 Query: 87 LHYADLTDASSLRRWIDVIKP--DEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAV 144 D+TD ++ + + P D V + AA V S E P V G + LL ++ Sbjct: 57 FAQLDVTDEAAFDKVFEA-HPDIDSVIHFAALKAVGESGEKPLDYYHVNVYGTICLLRSM 115 Query: 145 RSHTIDSGRTVKYYQAGSSEMFGSTPP-----PQSETTPFHPRSPYAASKCAAHWYTVNY 199 H + + S+ ++G P E P P +PY +K A + Sbjct: 116 VRHNV-----TNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIELAITDV 170 Query: 200 REAYGLFA-----------CNGIL---FN----HESPRRGEN--FVTRKITRALGRIKVG 239 A A NG L FN H S GE+ V + L ++ G Sbjct: 171 INAQRNNAKKAGNETEAAKWNGALLRYFNPAGAHPSGIMGEDPQGVPYNLLPLLAQVATG 230 Query: 240 LQTKLFL-GNLQASRDWGFAGDYVEAMWLMLQQEKPDDYV-----------VATEEGHTV 287 + KL + G+ AS D DY+ + L K +Y+ + T G TV Sbjct: 231 KREKLLVFGDDYASHDGTAIRDYIHILDLADGHLKALNYLRANNPGVRAWNLGTGRGSTV 290 Query: 288 EEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMM 347 E + +G + E+ R R +V NL + ++A LGWK Q E+ Sbjct: 291 YEMIRAFSKAVGRDLP--YEVAPR--RAGDVLNLTSNPTRANTELGWKAQRTLEQAC--- 343 Query: 348 VDEDLELAKREKVLVDAGYMDAKQQP 373 EDL L + GY +QQP Sbjct: 344 --EDLWLWTKNN---PQGY---RQQP 361 >1RKX-A nrPDB Length = 357 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 84/347 (24%), Positives = 132/347 (38%), Gaps = 53/347 (15%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRS----SNFNTQRINHIYIDPHNVNKAL 84 K +TG TG G +L+ +L G V G + S F T R+ Sbjct: 10 KRVFVTGHTGFKGGWLSLWLQTMGATVKGYSLTAPTVPSLFETARV-----------ADG 58 Query: 85 MKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAV 144 M+ D+ D + L I +P+ V+++AAQ V +S+ P T G + LLEA+ Sbjct: 59 MQSEIGDIRDQNKLLESIREFQPEIVFHMAAQPLVRLSYSEPVETYSTNVMGTVYLLEAI 118 Query: 145 RS----HTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYR 200 R + + + K Y ++G E PY+ SK A T +YR Sbjct: 119 RHVGGVKAVVNITSDKCYD-NKEWIWG-----YRENEAMGGYDPYSNSKGCAELVTSSYR 172 Query: 201 EAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL------QTKLFLGNLQASRD 254 ++ A G + R N + AL RI + + + N A R Sbjct: 173 NSFFNPANYGQHGTAVATVRAGNVIGGG-DWALDRIVPDILRAFEQSQPVIIRNPHAIRP 231 Query: 255 WGFAGDYVEAMWLMLQQE-------------KPDDYVVATEEGHTVEEFLDVSFGYLGLN 301 W + + L+ Q+ P+D AT + VE+ V + G + Sbjct: 232 WQHVLEPLSGYLLLAQKLYTDGAEYAEGWNFGPND-ADATPVKNIVEQM--VKYWGEGAS 288 Query: 302 WKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMV 348 W ++D P E L+ D SKAK LGW P+ ++ +V Sbjct: 289 W----QLDGN-AHPHEAHYLKLDCSKAKMQLGWHPRWNLNTTLEYIV 330 >1Z45-A nrPDB Length = 699 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 75/341 (21%), Positives = 129/341 (37%), Gaps = 34/341 (9%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 KI L+TG G GS+ L+ GY+ + SN + + + + K + + Sbjct: 12 KIVLVTGGAGYIGSHTVVELIENGYDCV-VADNLSNSTYDSVARLEV----LTKHHIPFY 66 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 DL D L + K D V + A V S +IP G + LLE ++ + Sbjct: 67 EVDLCDRKGLEKVFKEYKIDSVIHFAGLKAVGESTQIPLRYYHNNILGTVVLLELMQQYN 126 Query: 149 IDSGRTVKYYQAGSSEMFGSTPP-----PQSETTPFHPRSPYAASKCAAH-----WYTVN 198 + K+ + S+ ++G P E P P +PY +K A Y + Sbjct: 127 VS-----KFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENILNDLYNSD 181 Query: 199 YRE-AYGLFACNGILFNHESPRRGEN--FVTRKITRALGRIKVGLQTKLFL-GNLQASRD 254 + + + + H S GE+ + + + ++ VG + KL++ G+ SRD Sbjct: 182 KKSWKFAILRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDYDSRD 241 Query: 255 WGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDY------VEI 308 DY+ + L Y+ A E + ++ G ++ Y I Sbjct: 242 GTPIRDYIHVVDLAKGHIAALQYLEAYNENEGLCREWNLGSGKGSTVFEVYHAFCKASGI 301 Query: 309 DQRY----FRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVK 345 D Y R +V NL +AK L W+ ++ E K Sbjct: 302 DLPYKVTGRRAGDVLNLTAKPDRAKRELKWQTELQVEDSCK 342 >4R1T-A nrPDB Length = 337 Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 ++ +TG G S+L + LL KGY V G +R + + + K + L Sbjct: 11 QVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLREL-----EGAKERLTLC 65 Query: 89 YADLTDASSLRRWID 103 ADL D SLR I+ Sbjct: 66 KADLLDYQSLREAIN 80 >1ZZE-A nrPDB Length = 342 Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 19 KADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNF-NTQR 69 K D+ V+ + L+TG G S++ E LL GY+V G R +S N Q+ Sbjct: 2 KIDNAVLPEGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQK 53 >2NNL-D nrPDB Length = 337 Score = 32.3 bits (72), Expect = 0.30, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Query: 32 LITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYAD 91 +TG +G GS+L LL +GY V +R + N +++ H+ P + + L AD Sbjct: 9 CVTGASGFIGSWLVMRLLERGYTVRATVRDPT--NVKKVKHLLDLPK--AETHLTLWKAD 64 Query: 92 LTDASSLRRWI 102 L D S I Sbjct: 65 LADEGSFDEAI 75 >4WOK-A nrPDB Length = 336 Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust. Identities = 40/159 (25%), Positives = 63/159 (39%), Gaps = 16/159 (10%) Query: 91 DLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTID 150 D+ D + L ++ P V + AA ++V S E P G LL+A R Sbjct: 61 DILDQARLVETMEKYAPVAVIHFAASAYVGESVEDPAKYYRNNVGGTQSLLDACRLT--- 117 Query: 151 SGRTVKYYQAGSSEMFG-STPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGL---- 205 RT + S +G + P E +P +PY +K A +Y AYGL Sbjct: 118 --RTQNVIFSSSCATYGVPSRLPIGEGEAQNPINPYGRTKLIAEHMLADYAVAYGLRYVA 175 Query: 206 ---FACNGILFNHESPRRGE---NFVTRKITRALGRIKV 238 F +G + E + + + + R + A GR+ V Sbjct: 176 LRYFNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDV 214 >2P4H-X nrPDB Length = 322 Score = 32.0 bits (71), Expect = 0.50, Method: Compositional matrix adjust. Identities = 43/145 (29%), Positives = 65/145 (44%), Gaps = 26/145 (17%) Query: 31 ALITGITGQDGSYLTEFLLGKGYEVHGLIR------RSSNFNTQRINHIYIDPHNVNKAL 84 +TG TG GS++ + LL GY V+ IR R +F T N+ A Sbjct: 4 VCVTGGTGFLGSWIIKSLLENGYSVNTTIRADPERKRDVSFLT-----------NLPGAS 52 Query: 85 MKLHY--ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLE 142 KLH+ ADL++ S I+ +++ A+ AVS E + GAL +L+ Sbjct: 53 EKLHFFNADLSNPDSFAAAIEGCV--GIFHTASPIDFAVS-EPEEIVTKRTVDGALGILK 109 Query: 143 A-VRSHTIDSGRTVKYYQAGSSEMF 166 A V S T+ + Y +GS+ F Sbjct: 110 ACVNSKTV---KRFIYTSSGSAVSF 131 >4R1U-A nrPDB Length = 349 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 22 STVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVN 81 S+V + +TG G S+L + LL +GY V G +R + + + Sbjct: 21 SSVSGGDQTVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKEL-----EGA 75 Query: 82 KALMKLHYADLTDASSLRRWI 102 + + LH DL D S++ + Sbjct: 76 RERLTLHKVDLLDLQSIQSVV 96 >3ENK-A nrPDB Length = 341 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 77/331 (23%), Positives = 118/331 (35%), Gaps = 31/331 (9%) Query: 32 LITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYAD 91 L+TG G GS+ LL GY+V + + N++R I+ + H D Sbjct: 9 LVTGGAGYIGSHTAVELLAHGYDV---VIADNLVNSKREAIARIE--KITGKTPAFHETD 63 Query: 92 LTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTIDS 151 ++D +L R D + AA V S P L LL +R Sbjct: 64 VSDERALARIFDAHPITAAIHFAALKAVGESVAKPIEYYRNNLDSLLSLLRVMRE----- 118 Query: 152 GRTVKYYQAGSSEMFGSTP--PPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFACN 209 R VK SS P P ET P +PY +K A + A + Sbjct: 119 -RAVKRIVFSSSATVYGVPERSPIDETFPLSATNPYGQTKLMAEQILRDVEAADPSWRVA 177 Query: 210 GI-LFN----HESPRRGEN--FVTRKITRALGRIKVGLQTKL-FLGNLQASRDWGFAGDY 261 + FN HES GE+ + + + ++ VG KL G+ + D DY Sbjct: 178 TLRYFNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDY 237 Query: 262 VEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLN-WKDYVEIDQRYF------- 313 + + L D + + TV L GY L + + + R Sbjct: 238 IHVVDLARGHIAALDALERRDASLTVN--LGTGRGYSVLEVVRAFEKASGRAVPYELVAR 295 Query: 314 RPAEVDNLQGDASKAKEVLGWKPQVGFEKLV 344 RP +V + + A E +GWK + E++ Sbjct: 296 RPGDVAECYANPAAAAETIGWKAERDLERMC 326 >4QUK-A nrPDB Length = 319 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 12/44 (27%), Positives = 25/44 (56%), Gaps = 2/44 (4%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHI 73 + +TG +G S+L LL +GY V +R + + ++++H+ Sbjct: 2 VVCVTGASGYIASWLVRLLLHRGYTVKATVRDPN--DPKKVDHL 43 >5Z6T-A nrPDB Length = 343 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 11/73 (15%) Query: 31 ALITGITGQDGS--YLTEFLLGKGYEV---HGLIRRSSNFNTQRINHIYIDPHNVNKAL- 84 A+ TG DG+ Y E L+G G + G+++R F T ++ + Y P NV KAL Sbjct: 59 AIKTGYRLFDGAEDYANEKLVGAGVKKAIDEGIVKREDLFLTSKLWNNYHHPDNVEKALN 118 Query: 85 -----MKLHYADL 92 +++ Y DL Sbjct: 119 RTLSDLQVDYVDL 131 >2V6G-A nrPDB Length = 364 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 9/76 (11%) Query: 30 IALITGITGQDGSYLTEFL-----LGKGYEVHGLIRRS--SNFNTQRINHIYIDPHNVNK 82 +ALI G+TG G+ L E L G ++V+G+ RR+ + IN++ D + + Sbjct: 3 VALIVGVTGIIGNSLAEILPLADTPGGPWKVYGVARRTRPAWHEDNPINYVQCDISDPDD 62 Query: 83 ALMKLHYADLTDASSL 98 + KL + LTD + + Sbjct: 63 SQAKL--SPLTDVTHV 76 >6G4Q-B nrPDB Length = 415 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 5/46 (10%) Query: 81 NKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIP 126 + L L DL +A+ + V+K E+ LA Q+HV V F++P Sbjct: 372 DSGLKILACDDLDEAARM-----VVKLSEIVTLAKQAHVDVKFQLP 412 >5ZCM-A nrPDB Length = 341 Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 6/42 (14%) Query: 57 GLIRRSSNFNTQRINHIYIDPHNVNKAL------MKLHYADL 92 GL+ R F T ++ + Y DP NV AL MKL Y DL Sbjct: 85 GLVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDL 126 >1K8C-A nrPDB Length = 322 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 6/42 (14%) Query: 57 GLIRRSSNFNTQRINHIYIDPHNVNKAL------MKLHYADL 92 GL++R F T ++ + Y DP NV AL +K+ Y DL Sbjct: 69 GLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDL 110 >3SXP-A nrPDB Length = 362 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 47/212 (22%), Positives = 84/212 (39%), Gaps = 15/212 (7%) Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 AD+ + LRR ++ + D +++ AA S + + + L LLE RS Sbjct: 75 ADINNPLDLRR-LEKLHFDYLFHQAAVSDTTMLNQ--ELVMKTNYQAFLNLLEIARS--- 128 Query: 150 DSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFACN 209 + K A S+ ++G+T P P + Y SK + +++ Sbjct: 129 ---KKAKVIYASSAGVYGNTKAPNVVGKNESPENVYGFSKLCMDEFVLSHSNDNVQVGLR 185 Query: 210 GILFNHESPRR--GENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL 267 FN PR E + + ALG + + KLF Q RD+ + D ++A Sbjct: 186 --YFNVYGPREFYKEKTASMVLQLALGAMAFK-EVKLFEFGEQL-RDFVYIEDVIQANVK 241 Query: 268 MLQQEKPDDYVVATEEGHTVEEFLDVSFGYLG 299 ++ +K Y V + + E + + +LG Sbjct: 242 AMKAQKSGVYNVGYSQARSYNEIVSILKEHLG 273 >3U9L-A nrPDB Length = 324 Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 5/84 (5%) Query: 24 VVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHI--YIDPHNVN 81 +V +KI LITG + G E L G G+ V+ +R N + I + ++V+ Sbjct: 1 MVMSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVD 60 Query: 82 KALMKLHYADLTDASSLRRWIDVI 105 ++L D+ S+ R ID I Sbjct: 61 LRTLEL---DVQSQVSVDRAIDQI 81 >5U9C-A nrPDB Length = 292 Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust. Identities = 26/73 (35%), Positives = 32/73 (43%), Gaps = 4/73 (5%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 RKI LITG TG G+Y+T L Y V R + N + YI K + L Sbjct: 6 RKI-LITGGTGMLGAYVTSALKDTDYNVIVTERNTLNLSVPEAIFSYI---TAEKPDVIL 61 Query: 88 HYADLTDASSLRR 100 H+A TD R Sbjct: 62 HFAAETDVDLCER 74 >6CE1-A nrPDB Length = 686 Score = 28.5 bits (62), Expect = 5.0, Method: Compositional matrix adjust. Identities = 16/54 (29%), Positives = 26/54 (48%) Query: 318 VDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLVDAGYMDAKQ 371 VD+ Q +VL K + + K V+ +D + E+ KRE L + +D Q Sbjct: 540 VDDEQVKTISINQVLSNKDLINYNKFVQSCIDWNREVLKRELGLAECDIIDIPQ 593 >5EX8-A nrPDB Length = 424 Score = 28.1 bits (61), Expect = 7.3, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 7/58 (12%) Query: 256 GFAGDYVEAM-----WLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEI 308 G A D V + WLM++Q P + + E+ TV E+LD + YL + K + + Sbjct: 264 GAAADQVARLLAAGAWLMVEQ--PAQFALLREKPETVPEWLDETMRYLTTDEKTHPRV 319 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1N7G-A nrPDB 535 e-152 1DB3-A nrPDB 406 e-114 6GPK-A nrPDB 396 e-111 5UZH-A nrPDB 395 e-110 2Z95-A nrPDB 372 e-103 1RPN-A nrPDB 365 e-101 2HUN-A nrPDB 322 1e-88 6BI4-A nrPDB 319 2e-87 1BXK-A nrPDB 315 2e-86 1KEU-A nrPDB 312 2e-85 1OC2-A nrPDB 308 2e-84 1R66-A nrPDB 294 5e-80 2PK3-A nrPDB 286 8e-78 4LIS-A nrPDB 272 2e-73 1Z45-A nrPDB 270 5e-73 1ORR-A nrPDB 270 6e-73 3RUE-A nrPDB 267 8e-72 2PZM-A nrPDB 241 4e-64 2C20-A nrPDB 240 1e-63 1RKX-A nrPDB 239 1e-63 1WVG-A nrPDB 231 4e-61 2Q1W-A nrPDB 227 9e-60 1GY8-A nrPDB 222 2e-58 Sequences not found previously or not previously below threshold: 1UDA-A nrPDB 213 9e-56 1I3M-A nrPDB 207 8e-54 4WOK-A nrPDB 191 3e-49 3ENK-A nrPDB 189 1e-48 6BWL-A nrPDB 173 8e-44 2Q1T-A nrPDB 144 7e-35 3SXP-A nrPDB 135 2e-32 2C54-A nrPDB 111 4e-25 1EQ2-A nrPDB 105 3e-23 2X86-A nrPDB 102 2e-22 4WKG-A nrPDB 101 4e-22 3M2P-A nrPDB 95 4e-20 1GFS-A nrPDB 94 8e-20 3WMX-A nrPDB 87 1e-17 4G5H-A nrPDB 84 1e-16 3SC6-A nrPDB 84 1e-16 4EJ0-A nrPDB 84 1e-16 4KTT-E nrPDB 83 2e-16 2NNL-D nrPDB 81 6e-16 5B6K-A nrPDB 80 2e-15 4J2O-A nrPDB 79 2e-15 2P4H-X nrPDB 76 2e-14 1VL0-A nrPDB 75 5e-14 4BKP-A nrPDB 74 1e-13 4WPG-A nrPDB 73 2e-13 2GN9-A nrPDB 72 4e-13 4R1T-A nrPDB 71 8e-13 3HFS-A nrPDB 66 2e-11 3RFT-A nrPDB 66 2e-11 2GGS-A nrPDB 66 2e-11 4R1U-A nrPDB 65 6e-11 4PVC-A nrPDB 64 8e-11 6AQY-A nrPDB 63 2e-10 5U9C-A nrPDB 62 5e-10 1KC3-A nrPDB 59 2e-09 1ZZE-A nrPDB 58 9e-09 4QQR-A nrPDB 56 3e-08 4QUK-A nrPDB 56 4e-08 6GCS-E nrPDB 54 7e-08 4NBT-A nrPDB 48 5e-06 1K2W-A nrPDB 48 6e-06 4AVY-A nrPDB 47 1e-05 3SLK-A nrPDB 47 1e-05 5YWN-A nrPDB 46 2e-05 5U9P-A nrPDB 44 7e-05 3PVZ-A nrPDB 44 8e-05 5ILO-A nrPDB 44 9e-05 2FWM-X nrPDB 43 2e-04 3WOH-A nrPDB 42 4e-04 4B4O-A nrPDB 42 5e-04 3U9L-A nrPDB 41 7e-04 6CGE-A nrPDB 40 0.002 1A27-A nrPDB 40 0.002 3A28-C nrPDB 40 0.002 1QYD-A nrPDB 40 0.002 2V6G-A nrPDB 40 0.002 2GDZ-A nrPDB 39 0.002 1GEG-A nrPDB 39 0.002 4E6P-A nrPDB 39 0.002 1YXM-A nrPDB 39 0.003 3U5T-A nrPDB 39 0.003 3PXX-A nrPDB 39 0.003 4DBZ-A nrPDB 39 0.004 3OSU-A nrPDB 39 0.004 1UZM-A nrPDB 38 0.005 2NM0-A nrPDB 38 0.006 3RWB-A nrPDB 38 0.006 5D01-A nrPDB 38 0.006 4BO1-A nrPDB 38 0.007 1CYD-A nrPDB 38 0.010 4IS3-A nrPDB 38 0.010 5OVL-A nrPDB 38 0.011 5OVJ-A nrPDB 38 0.011 3RKU-A nrPDB 37 0.011 3V2G-A nrPDB 37 0.012 3KZV-A nrPDB 37 0.013 4MOW-A nrPDB 37 0.015 6CI9-A nrPDB 37 0.015 3UN1-A nrPDB 37 0.017 3OEC-A nrPDB 36 0.019 3D3W-A nrPDB 36 0.019 5ITV-A nrPDB 36 0.020 5CDY-A nrPDB 36 0.024 3V8B-A nrPDB 36 0.026 5VT6-A nrPDB 36 0.030 3RSH-A nrPDB 36 0.030 6NRP-A nrPDB 36 0.033 3WTC-A nrPDB 36 0.034 2HRB-A nrPDB 35 0.044 2UVD-A nrPDB 35 0.051 4RZI-B nrPDB 35 0.053 1HE4-A nrPDB 35 0.053 4K6F-A nrPDB 35 0.058 3ZV3-A nrPDB 35 0.064 4KMS-A nrPDB 35 0.065 2BC1-A nrPDB 34 0.070 6D9T-A nrPDB 34 0.087 2QYS-A nrPDB 34 0.090 1H5Q-A nrPDB 34 0.097 3WYE-A nrPDB 34 0.11 3KYB-A nrPDB 33 0.19 5LCX-A nrPDB 33 0.21 1Q7C-A nrPDB 33 0.22 2B4Q-A nrPDB 33 0.26 3EZL-A nrPDB 32 0.28 4IIN-A nrPDB 32 0.30 5DBI-A nrPDB 32 0.35 2YV2-A nrPDB 32 0.42 3VZS-A nrPDB 32 0.42 3DWF-A nrPDB 32 0.43 3F9I-A nrPDB 32 0.45 2Q2Q-A nrPDB 32 0.46 1OOE-A nrPDB 32 0.46 1BDB-A nrPDB 32 0.51 5WQO-A nrPDB 32 0.54 4XRR-A nrPDB 32 0.55 4HP8-A nrPDB 32 0.55 6EL3-D nrPDB 31 0.60 3V48-A nrPDB 31 0.70 3K8Z-A nrPDB 31 0.76 6QX9-4B nrPDB 31 0.77 4Z9Y-A nrPDB 31 0.91 3EMK-A nrPDB 31 0.91 3E9N-A nrPDB 31 0.92 6HRD-A nrPDB 31 1.2 1O89-A nrPDB 30 1.4 3H0K-A nrPDB 30 1.5 3LYL-A nrPDB 30 1.6 4FQE-A nrPDB 30 1.7 1HXH-A nrPDB 30 1.7 5NR1-A nrPDB 30 1.9 2GU2-A nrPDB 30 1.9 5YSS-A nrPDB 30 2.1 2ZCU-A nrPDB 30 2.2 2O23-A nrPDB 29 2.4 1P33-A nrPDB 29 2.8 4RZH-A nrPDB 29 3.0 2DKN-A nrPDB 29 3.1 5GXF-A nrPDB 29 3.4 4FC7-A nrPDB 29 3.7 3K44-A nrPDB 29 3.8 4UUM-A nrPDB 29 4.2 4IIV-A nrPDB 29 4.2 1VCN-A nrPDB 29 4.3 5GUP-v nrPDB 27 8.6 >1N7G-A nrPDB Length = 381 Score = 535 bits (1379), Expect = e-152, Method: Composition-based stats. Identities = 373/373 (100%), Positives = 373/373 (100%) Query: 1 MASENNGSRSDSESITAPKADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIR 60 MASENNGSRSDSESITAPKADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIR Sbjct: 1 MASENNGSRSDSESITAPKADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIR 60 Query: 61 RSSNFNTQRINHIYIDPHNVNKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVA 120 RSSNFNTQRINHIYIDPHNVNKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVA Sbjct: 61 RSSNFNTQRINHIYIDPHNVNKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVA 120 Query: 121 VSFEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH 180 VSFEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH Sbjct: 121 VSFEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH 180 Query: 181 PRSPYAASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL 240 PRSPYAASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL Sbjct: 181 PRSPYAASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL 240 Query: 241 QTKLFLGNLQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGL 300 QTKLFLGNLQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGL Sbjct: 241 QTKLFLGNLQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGL 300 Query: 301 NWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKV 360 NWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKV Sbjct: 301 NWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKV 360 Query: 361 LVDAGYMDAKQQP 373 LVDAGYMDAKQQP Sbjct: 361 LVDAGYMDAKQQP 373 >1DB3-A nrPDB Length = 372 Score = 406 bits (1044), Expect = e-114, Method: Composition-based stats. Identities = 195/367 (53%), Positives = 255/367 (69%), Gaps = 31/367 (8%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 K+ALITG+TGQDGSYL EFLL KGYEVHG+ RR+S+FNT+R++HIY DPH N L Sbjct: 1 SKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKF-HL 59 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 HY DL+D S+L R + ++PDEVYNL A SHVAVSFE P+YTADV A G LRLLEA+R Sbjct: 60 HYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAIRFL 119 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLF 206 ++ + ++YQA +SE++G PQ ETTPF+PRSPYA +K A+W TVNYRE+YG++ Sbjct: 120 GLE--KKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKLYAYWITVNYRESYGMY 177 Query: 207 ACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMW 266 ACNGILFNHESPRRGE FVTRKITRA+ I GL++ L+LGN+ + RDWG A DYV+ W Sbjct: 178 ACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKMQW 237 Query: 267 LMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWK----------------------- 303 +MLQQE+P+D+V+AT ++V +F++++ LG+ + Sbjct: 238 MMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAPGV 297 Query: 304 ----DYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREK 359 + +D RYFRPAEV+ L GD +KA E LGWKP++ ++V MV DLE AK+ Sbjct: 298 KPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMVANDLEAAKKHS 357 Query: 360 VLVDAGY 366 +L GY Sbjct: 358 LLKSHGY 364 >6GPK-A nrPDB Length = 373 Score = 396 bits (1018), Expect = e-111, Method: Composition-based stats. Identities = 192/349 (55%), Positives = 251/349 (71%), Gaps = 20/349 (5%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 R +ALITGITGQDGSYL EFLL KGYEVHG++RRSS+FNT RI H+Y +P + MKL Sbjct: 24 RNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKL 83 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 HY DLTD++ L + I+ +KP E+YNL AQSHV +SF++ +YTADV G LRLL+AV++ Sbjct: 84 HYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTC 143 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLF 206 + + +VK+YQA +S+++G PQ ETTPF+PRSPY A+K A+W VN+REAY LF Sbjct: 144 GLIN--SVKFYQASTSQLYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLF 201 Query: 207 ACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMW 266 A NGILFNHESPRRG NFVTRKI+R++ +I +G LGNL A RDWG A DYVEAMW Sbjct: 202 AVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMW 261 Query: 267 LMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNW-----------------KDYVEID 309 LMLQ ++P+D+V+AT E H+V EF++ SF ++G K +V +D Sbjct: 262 LMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWEGKNENEVGRCKETGKVHVTVD 321 Query: 310 QRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKRE 358 +Y+RP EVD LQGD +KAK+ L WKP+V F++LV+ MV D+EL + Sbjct: 322 LKYYRPTEVDFLQGDCTKAKQKLNWKPRVAFDELVREMVHADVELMRTN 370 >5UZH-A nrPDB Length = 345 Score = 395 bits (1014), Expect = e-110, Method: Composition-based stats. Identities = 201/347 (57%), Positives = 247/347 (71%), Gaps = 21/347 (6%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 K+ALITGITGQDGSYL EFLL KGY V+G+IRRSS+FNT R+ H+Y D H + KA KL Sbjct: 1 SKVALITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIH-ITKAKFKL 59 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 Y DLTD +L I IKPDE+YNLAAQSHV VSFE+P+YTA+V G LRLLEA+R+ Sbjct: 60 LYGDLTDTGNLISIIAKIKPDEIYNLAAQSHVKVSFEMPEYTANVDGIGTLRLLEAIRAC 119 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLF 206 ++ + K+YQA +SE++G PQ ETTPF+PRSPYA +K ++W VNYREAY +F Sbjct: 120 GLE--KKTKFYQASTSELYGLVQEVPQKETTPFYPRSPYACAKLYSYWIVVNYREAYNMF 177 Query: 207 ACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMW 266 A NGILFNHES RRG FVTRKIT A+ RIK+GLQ L+LGNL A RDWG A DYVEAMW Sbjct: 178 ALNGILFNHESIRRGPTFVTRKITMAVARIKLGLQDCLYLGNLDAERDWGHAKDYVEAMW 237 Query: 267 LMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWK-----------------DYVEID 309 LMLQQE+P D+ VAT E H+V EF++ +F +G + V +D Sbjct: 238 LMLQQEQPRDFCVATGEKHSVREFVEKAFACIGQTVEWKGERGTVEEHGVVDGVVRVRVD 297 Query: 310 QRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAK 356 RYFRP EVD L GD + A+ VLGWK +V FE+LV+ MV+ D+EL + Sbjct: 298 PRYFRPTEVDQLLGDPTLAETVLGWKRKVSFEELVRGMVEGDIELLQ 344 >2Z95-A nrPDB Length = 345 Score = 372 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 185/352 (52%), Positives = 237/352 (67%), Gaps = 28/352 (7%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K ALITGI GQDG+YL + LL KGYEV+G RRS F + R+ + I+ +K+ Sbjct: 4 KRALITGIRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIEND------VKII 57 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 + DL + S++ R I+ ++PDEVYNLAAQS V VSFE P TA+V A G LR+LEA+R+ Sbjct: 58 HMDLLEFSNIIRTIEKVQPDEVYNLAAQSFVGVSFEQPILTAEVDAIGVLRILEALRTVK 117 Query: 149 IDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 D K+YQA +SEMFG PQ+E TPF+PRSPYA +K HW TVNYREAY +FA Sbjct: 118 PD----TKFYQASTSEMFGKVQEIPQTEKTPFYPRSPYAVAKLFGHWITVNYREAYNMFA 173 Query: 208 CNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL 267 C+GILFNHESP RG FVTRKIT +L RIK GLQ KL LGNL A RDWG+A +YVEAMWL Sbjct: 174 CSGILFNHESPLRGIEFVTRKITYSLARIKYGLQDKLVLGNLNAKRDWGYAPEYVEAMWL 233 Query: 268 MLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNW-----------------KDYVEIDQ 310 M+QQ +PDDYV+AT E HTV EF++ + G + K VE+ + Sbjct: 234 MMQQPEPDDYVIATGETHTVREFVEKAAKIAGFDIEWVGEGINEKGIDRNTGKVIVEVSE 293 Query: 311 RYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLV 362 +FRPAEVD L G+ KA + LGWKP+ F++LV++M++ DL+ + +V V Sbjct: 294 EFFRPAEVDILVGNPEKAMKKLGWKPRTTFDELVEIMMEADLKRVRDREVSV 345 >1RPN-A nrPDB Length = 335 Score = 365 bits (936), Expect = e-101, Method: Composition-based stats. Identities = 169/331 (51%), Positives = 224/331 (67%), Gaps = 11/331 (3%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 + AL+TGITGQDG+YL + LL KGY VHGL+ R S+ R+ + I+ ++ Sbjct: 15 RSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGD------IQYE 68 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 D+ DA S++R + +P EVYNLAAQS V S+ P T V G LLEA+R + Sbjct: 69 DGDMADACSVQRAVIKAQPQEVYNLAAQSFVGASWNQPVTTGVVDGLGVTHLLEAIRQFS 128 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPP-QSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 + ++YQA +SEMFG Q E TPF+PRSPY +K HW TVNYRE++GL A Sbjct: 129 PE----TRFYQASTSEMFGLIQAERQDENTPFYPRSPYGVAKLYGHWITVNYRESFGLHA 184 Query: 208 CNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL 267 +GILFNHESP RG FVTRK+T A+ RIK+G Q +L LGN+ A RDWGFAGDYVEAMWL Sbjct: 185 SSGILFNHESPLRGIEFVTRKVTDAVARIKLGKQQELRLGNVDAKRDWGFAGDYVEAMWL 244 Query: 268 MLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDASK 327 MLQQ+K DDYVVAT TV + ++F ++GL+++D+++ID +FRPAEVD L G+ +K Sbjct: 245 MLQQDKADDYVVATGVTTTVRDMCQIAFEHVGLDYRDFLKIDPAFFRPAEVDVLLGNPAK 304 Query: 328 AKEVLGWKPQVGFEKLVKMMVDEDLELAKRE 358 A+ VLGWKP+ ++L++MMV+ DL RE Sbjct: 305 AQRVLGWKPRTSLDELIRMMVEADLRRVSRE 335 >2HUN-A nrPDB Length = 336 Score = 322 bits (825), Expect = 1e-88, Method: Composition-based stats. Identities = 82/339 (24%), Positives = 143/339 (42%), Gaps = 23/339 (6%) Query: 30 IALITGITGQDGSYLTEFLLGKG--YEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 L+TG G GS ++L K +EV + + N + + DP Sbjct: 5 KLLVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPRY------TF 58 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 D+ D ++ + K D V +LAA+SHV S P+ G LLE++R Sbjct: 59 VKGDVADYELVKELVR--KVDGVVHLAAESHVDRSISSPEIFLHSNVIGTYTLLESIRRE 116 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPPP-QSETTPFHPRSPYAASKCAAHWYTVNYREAYGLF 206 + V++ + E++G +E P SPY+A+K A+ + + Y L Sbjct: 117 NPE----VRFVHVSTDEVYGDILKGSFTENDRLMPSSPYSATKAASDMLVLGWTRTYNLN 172 Query: 207 ACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMW 266 A N+ P + F + I + + R +GL+ ++ G + RDW + D+V A+ Sbjct: 173 ASITRCTNNYGPYQ---FPEKLIPKTIIRASLGLKIPIY-GTGKNVRDWLYVEDHVRAIE 228 Query: 267 LMLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDA 325 L+L + + + Y ++ E T E + + +G + I+ RP D+ Sbjct: 229 LVLLKGESREIYNISAGEEKTNLEVVKIILRLMGKGEEL---IELVEDRPGHDLRYSLDS 285 Query: 326 SKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLVDA 364 K L W+P+ F++ +K +D L+ K LVD Sbjct: 286 WKITRDLKWRPKYTFDEGIKKTIDWYLKNEWWWKPLVDE 324 >6BI4-A nrPDB Length = 346 Score = 319 bits (816), Expect = 2e-87, Method: Composition-based stats. Identities = 82/337 (24%), Positives = 139/337 (41%), Gaps = 21/337 (6%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 L+TG G GS ++L + YE + +I + + +N++ + N +K Sbjct: 26 NILVTGGAGFIGSNFVHYML-QSYETYKIINFDALTYSGNLNNVKSIQDHPNYYFVK--- 81 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 ++ + L I + N AA+SHV S E P D G + LLE V+ + Sbjct: 82 GEIQNGELLEHVIKERDVQVIVNFAAESHVDRSIENPIPFYDTNVIGTVTLLELVKKYP- 140 Query: 150 DSGRTVKYYQAGSSEMFGSTPPP--QSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 +K Q + E++GS +E TP P SPY++SK +A + Y + Y L Sbjct: 141 ----HIKLVQVSTDEVYGSLGKTGRFTEETPLAPNSPYSSSKASADMIALAYYKTYQLPV 196 Query: 208 CNGILFNHESPRR-GENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMW 266 N+ P + E + +T AL G + L+ G+ RDW D+ A+ Sbjct: 197 IVTRCSNNYGPYQYPEKLIPLMVTNALE----GKKLPLY-GDGLNVRDWLHVTDHCSAID 251 Query: 267 LMLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDA 325 ++L + + + Y + T E ++ LG KD I+ R +A Sbjct: 252 VVLHKGRVGEVYNIGGNNEKTNVEVVEQIITLLGKTKKD---IEYVTDRLGHDRRYAINA 308 Query: 326 SKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLV 362 K K W+P+ FE+ ++ V + + K L Sbjct: 309 EKMKNEFDWEPKYTFEQGLQETVQWYEKNEEWWKPLK 345 >1BXK-A nrPDB Length = 355 Score = 315 bits (807), Expect = 2e-86, Method: Composition-based stats. Identities = 90/362 (24%), Positives = 139/362 (38%), Gaps = 33/362 (9%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 + LITG G GS L +++ + + ++ + T N + + P Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKL----TYAGNLMSLAP-VAQSERFAFE 56 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 D+ D + L R +PD V +LAA+SHV S + P + G LLEA R++ Sbjct: 57 KVDICDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNIVGTYTLLEAARAYW 116 Query: 149 ----IDSGRTVKYYQAGSSEMFGST---PPPQSETTPFHPRSPYAASKCAAHWYTVNYRE 201 D +++ + E++G +ETTP+ P SPY+ASK ++ + Sbjct: 117 NALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAWLR 176 Query: 202 AYGLFACNGILFNHESPRR-GENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGD 260 YGL N+ P E + I AL G ++ GN Q RDW + D Sbjct: 177 TYGLPTLITNCSNNYGPYHFPEKLIPLMILNALA----GKSLPVY-GNGQQIRDWLYVED 231 Query: 261 YVEAMWLMLQQEK-PDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVE-----------I 308 + A++ + K + Y + GH + LDV L + I Sbjct: 232 HARALYCVATTGKVGETYNIG---GHNERKNLDVVETICELLEELAPNKPHGVAHYRDLI 288 Query: 309 DQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLVDAGYMD 368 RP DASK LG PQ FE ++ V L K + D Y Sbjct: 289 TFVADRPGHDLRYAIDASKIARELGCVPQETFESGMRKTVQWYLANESWWKQVQDGSYQG 348 Query: 369 AK 370 + Sbjct: 349 ER 350 >1KEU-A nrPDB Length = 361 Score = 312 bits (798), Expect = 2e-85, Method: Composition-based stats. Identities = 86/367 (23%), Positives = 141/367 (38%), Gaps = 37/367 (10%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 LITG G GS + ++ + I + + + + + + Sbjct: 2 KILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLT--YAGNLESLSDISESNRYN---FEH 56 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 AD+ D++ + R + +PD V +LAA+SHV S P + G LLE R + Sbjct: 57 ADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVARKYWS 116 Query: 150 ----DSGRTVKYYQAGSSEMFGSTPPPQ-----------SETTPFHPRSPYAASKCAAHW 194 D +++ + E++G P P +ETT + P SPY+ASK ++ Sbjct: 117 ALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDH 176 Query: 195 YTVNYREAYGLFACNGILFNHESPRR-GENFVTRKITRALGRIKVGLQTKLFLGNLQASR 253 +R YGL N+ P E + I AL G ++ G R Sbjct: 177 LVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALE----GKPLPIY-GKGDQIR 231 Query: 254 DWGFAGDYVEAMWLMLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYV------ 306 DW + D+ A+ +++ + K + Y + GH ++ LDV F L + Sbjct: 232 DWLYVEDHARALHMVVTEGKAGETYNIG---GHNEKKNLDVVFTICDLLDEIVPKATSYR 288 Query: 307 -EIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLVDAG 365 +I RP DA K LGWKP FE ++ V+ L + + Sbjct: 289 EQITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLANTQWVNNVKSGA 348 Query: 366 YMDAKQQ 372 Y +Q Sbjct: 349 YQSWIEQ 355 >1OC2-A nrPDB Length = 348 Score = 308 bits (789), Expect = 2e-84, Method: Composition-based stats. Identities = 84/363 (23%), Positives = 144/363 (39%), Gaps = 42/363 (11%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K ++TG G GS ++ +VH + + + N I ++L Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDR-----VELV 59 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 D+ DA + + K D + + AA+SH S P G LLEA R + Sbjct: 60 VGDIADAELVDKL--AAKADAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKYD 117 Query: 149 IDSGRTVKYYQAGSSEMFGSTP-----PPQSE--------TTPFHPRSPYAASKCAAHWY 195 I +++ + E++G P P E T ++P SPY+++K A+ Sbjct: 118 I------RFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSPYSSTKAASDLI 171 Query: 196 TVNYREAYGLFACNGILFNHESPR-RGENFVTRKITRALGRIKVGLQTKLFLGNLQASRD 254 + ++G+ A N+ P E F+ R+IT L IK G + RD Sbjct: 172 VKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILAGIK-----PKLYGEGKNVRD 226 Query: 255 WGFAGDYVEAMWLMLQQEK-PDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYF 313 W D+ +W +L + + + Y++ + +E L++ +G Y D Sbjct: 227 WIHTNDHSTGVWAILTKGRMGETYLIGADGEKNNKEVLELILEKMGQPKDAY---DHVTD 283 Query: 314 RPAEVDNLQGDASKAKEVLGWKPQVG-----FEKLVKMMVDEDLELAKREKVLVDAGYMD 368 R DASK ++ LGW PQ E+ ++ D + + K EK V+A Y Sbjct: 284 RAGHDLRYAIDASKLRDELGWTPQFTDFSEGLEETIQWYTD-NQDWWKAEKEAVEANYAK 342 Query: 369 AKQ 371 ++ Sbjct: 343 TQE 345 >1R66-A nrPDB Length = 337 Score = 294 bits (751), Expect = 5e-80, Method: Composition-based stats. Identities = 77/340 (22%), Positives = 125/340 (36%), Gaps = 26/340 (7%) Query: 30 IALITGITGQDGSYLTEFLLGKGY-EV---HGLIRRSSNFNTQRINHIYIDPHNVNKALM 85 L+TG G GS+ LL Y +V ++ S + R N +D + Sbjct: 2 RLLVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLTYAGNRANLAPVDADP----RL 57 Query: 86 KLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVR 145 + + D+ DA L R + + D + + AA+SHV S + G LL+ Sbjct: 58 RFVHGDIRDAGLLARELRGV--DAIVHFAAESHVDRSIAGASVFTETNVQGTQTLLQCAV 115 Query: 146 SHTIDSGRTVKYYQAGSSEMFGSTPPPQ-SETTPFHPRSPYAASKCAAHWYTVNYREAYG 204 + + + E++GS +E++P P SPYAASK + Y YG Sbjct: 116 DAGV-----GRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARAYHRTYG 170 Query: 205 LFACNGILFNHESPR-RGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVE 263 L N+ P E + +T L G L+ G+ R+W D+ Sbjct: 171 LDVRITRCCNNYGPYQHPEKLIPLFVTNLLD----GGTLPLY-GDGANVREWVHTDDHCR 225 Query: 264 AMWLMLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQ 322 + L+L + + Y + T E + LG +W ++ R Sbjct: 226 GIALVLAGGRAGEIYHIGGGLELTNRELTGILLDSLGADWSSVRKVADRK---GHDLRYS 282 Query: 323 GDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLV 362 D K + LG++PQV F + V E + L Sbjct: 283 LDGGKIERELGYRPQVSFADGLARTVRWYRENRGWWEPLK 322 >2PK3-A nrPDB Length = 321 Score = 286 bits (732), Expect = 8e-78, Method: Composition-based stats. Identities = 100/327 (30%), Positives = 152/327 (46%), Gaps = 27/327 (8%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 ALITG+ G G YL L + EV F T R N + +++ Sbjct: 14 RALITGVAGFVGKYLANHLTEQNVEV---------FGTSRNNEAKLP-------NVEMIS 57 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 D+ D+ +++ I IKPD +++LAA+S V S+ T G L +L+AVR + Sbjct: 58 LDIMDSQRVKKVISDIKPDYIFHLAAKSSVKDSWLNKKGTFSTNVFGTLHVLDAVRDSNL 117 Query: 150 DSGRTVKYYQAGSSEMFGSTPP---PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLF 206 D + GSSE +G P P SE P SPY SK + Y +AYG+ Sbjct: 118 DC----RILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAYGMD 173 Query: 207 ACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLF-LGNLQASRDWGFAGDYVEAM 265 + FNH P + FVT+ + + I++ Q + +GNL+A RD+ D V+A Sbjct: 174 IIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDFTDVRDIVQAY 233 Query: 266 WLMLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGD 324 WL+ Q K D Y V + G +++ LD+ N K E++ RP+EV L G Sbjct: 234 WLLSQYGKTGDVYNVCSGIGTRIQDVLDLLLAM--ANVKIDTELNPLQLRPSEVPTLIGS 291 Query: 325 ASKAKEVLGWKPQVGFEKLVKMMVDED 351 + K+ GWKP++ EK + ++ Sbjct: 292 NKRLKDSTGWKPRIPLEKSLFEILQSY 318 >4LIS-A nrPDB Length = 371 Score = 272 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 95/385 (24%), Positives = 144/385 (37%), Gaps = 63/385 (16%) Query: 27 PRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMK 86 P L+TG TG GS+ T LL GY+V + N + + +N I + ++ + Sbjct: 2 PSGSVLVTGGTGYIGSFTTLALLEAGYKVV-VADNLYNSSAEALNRIEL----ISGKKAE 56 Query: 87 LHYADLTDASSLRRWIDVI-KPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVR 145 D+TD ++ + + D V + AA V S E P V G + LL ++ Sbjct: 57 FAQLDVTDEAAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDYYHVNVYGTICLLRSMV 116 Query: 146 SHTIDSGRTVKYYQAGSSEMFGSTPP-----PQSETTPFHPRSPYAASKCAAHWYTVNYR 200 H + + S+ ++G P E P P +PY +K A + Sbjct: 117 RHNV-----TNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIELAITDVI 171 Query: 201 EAYGLFA-----------CNG---ILFN----HESPRRGEN--FVTRKITRALGRIKVGL 240 A A NG FN H S GE+ V + L ++ G Sbjct: 172 NAQRNNAKKAGNETEAAKWNGALLRYFNPAGAHPSGIMGEDPQGVPYNLLPLLAQVATGK 231 Query: 241 QTK-LFLGNLQASRDWGFAGDYVEAMWLMLQQEKPDDY-----------VVATEEGHTVE 288 + K L G+ AS D DY+ + L K +Y + T G TV Sbjct: 232 REKLLVFGDDYASHDGTAIRDYIHILDLADGHLKALNYLRANNPGVRAWNLGTGRGSTVY 291 Query: 289 EFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMV 348 E + +G + E+ R R +V NL + ++A LGWK Q E+ Sbjct: 292 EMIRAFSKAVGRDLP--YEVAPR--RAGDVLNLTSNPTRANTELGWKAQRTLEQAC---- 343 Query: 349 DEDLELAKREKVLVDAGYMDAKQQP 373 EDL L + GY +QQP Sbjct: 344 -EDLWLWTKNN---PQGY---RQQP 361 >1Z45-A nrPDB Length = 699 Score = 270 bits (691), Expect = 5e-73, Method: Composition-based stats. Identities = 77/357 (21%), Positives = 131/357 (36%), Gaps = 39/357 (10%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 KI L+TG G GS+ L+ GY+ + SN + + + + K + Sbjct: 11 SKIVLVTGGAGYIGSHTVVELIENGYDCV-VADNLSNSTYDSVARLEV----LTKHHIPF 65 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 + DL D L + K D V + A V S +IP G + LLE ++ + Sbjct: 66 YEVDLCDRKGLEKVFKEYKIDSVIHFAGLKAVGESTQIPLRYYHNNILGTVVLLELMQQY 125 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPP-----PQSETTPFHPRSPYAASKCAAHWYTVNYREA 202 + K+ + S+ ++G P E P P +PY +K A + + Sbjct: 126 NVS-----KFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENILNDLYNS 180 Query: 203 ------YGLFACNGILFNHESPRRGEN--FVTRKITRALGRIKVGLQTKLFL-GNLQASR 253 + + + H S GE+ + + + ++ VG + KL++ G+ SR Sbjct: 181 DKKSWKFAILRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDYDSR 240 Query: 254 DWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDY------VE 307 D DY+ + L Y+ A E + ++ G ++ Y Sbjct: 241 DGTPIRDYIHVVDLAKGHIAALQYLEAYNENEGLCREWNLGSGKGSTVFEVYHAFCKASG 300 Query: 308 IDQRY----FRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKV 360 ID Y R +V NL +AK L W+ ++ E K DL E Sbjct: 301 IDLPYKVTGRRAGDVLNLTAKPDRAKRELKWQTELQVEDSCK-----DLWKWTTENP 352 >1ORR-A nrPDB Length = 347 Score = 270 bits (690), Expect = 6e-73, Method: Composition-based stats. Identities = 82/345 (23%), Positives = 126/345 (36%), Gaps = 36/345 (10%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 LITG G GS L F L +G ++ S T ++ + + + + Sbjct: 3 KLLITGGCGFLGSNLASFALSQGIDLIVFDNLSRKGATDNLHWL------SSLGNFEFVH 56 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 D+ + + + R I PD ++LA Q + S + P ++ G L LLEAVR + Sbjct: 57 GDIRNKNDVTRLITKYMPDSCFHLAGQVAMTTSIDNPCMDFEINVGGTLNLLEAVRQYNS 116 Query: 150 DSG-------------RTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYT 196 + KY + + P E+T SPY SK AA Y Sbjct: 117 NCNIIYSSTNKVYGDLEQYKYNETETRYTCVDKPNGYDESTQLDFHSPYGCSKGAADQYM 176 Query: 197 VNYREAYGLFACNGILFNHESPRRGENFVTRK------ITRALGRIKVGLQTKLFL-GNL 249 ++Y +GL N ++F H S G F T + IK G+ + GN Sbjct: 177 LDYARIFGL---NTVVFRHSSMYGGRQFATYDQGWVGWFCQKAVEIKNGINKPFTISGNG 233 Query: 250 QASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEID 309 + RD A D + + L G V +S L +DY ID Sbjct: 234 KQVRDVLHAEDMISLYFTALANVSKIRGNAFNIGGTIVN---SLSLLELFKLLEDYCNID 290 Query: 310 QRY----FRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDE 350 R+ R ++ D K + W P+V + V+ M D Sbjct: 291 MRFTNLPVRESDQRVFVADIKKITNAIDWSPKVSAKDGVQKMYDW 335 >3RUE-A nrPDB Length = 351 Score = 267 bits (681), Expect = 8e-72, Method: Composition-based stats. Identities = 82/335 (24%), Positives = 133/335 (39%), Gaps = 17/335 (5%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSS--NFNTQRINHIYIDPHNVNKALMK 86 K LITG+ G GS L E LL V GL S+ +N + + ++ Sbjct: 26 KTWLITGVAGFIGSNLLEKLLKLNQVVIGLDNFSTGHQYNLDEVKTLVSTEQWSRFCFIE 85 Query: 87 LHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRS 146 DLT + + + D V + AA V S P T TG L +L A ++ Sbjct: 86 GDIRDLTTCEQVMKGV-----DHVLHQAALGSVPRSIVDPITTNATNITGFLNILHAAKN 140 Query: 147 HTIDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGL 205 + S + A SS +G P P+ E +P SPYA +K Y Y YG Sbjct: 141 AQVQS-----FTYAASSSTYGDHPALPKVEENIGNPLSPYAVTKYVNEIYAQVYARTYGF 195 Query: 206 FACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAM 265 FN R+ N + + G+ + SRD+ + + ++ Sbjct: 196 KTIGLRYFNVFGRRQDPNGAYAAVIPKWTAAMLKGDDVYINGDGETSRDFCYIDNVIQMN 255 Query: 266 WL-MLQQEKPDD--YVVATEEGHTVEEFLDVSFGYLGL-NWKDYVEIDQRYFRPAEVDNL 321 L L ++ D Y VA + T+ E + L L + D + I R FR +V + Sbjct: 256 ILSALAKDSAKDNIYNVAVGDRTTLNELSGYIYDELNLIHHIDKLSIKYREFRSGDVRHS 315 Query: 322 QGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAK 356 Q D +KA ++L ++P + + +++ + + K Sbjct: 316 QADVTKAIDLLKYRPNIKIREGLRLSMPWYVRFLK 350 >2PZM-A nrPDB Length = 330 Score = 241 bits (615), Expect = 4e-64, Method: Composition-based stats. Identities = 80/332 (24%), Positives = 135/332 (40%), Gaps = 41/332 (12%) Query: 27 PRK---IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKA 83 PR LITG G GS L E L +G+E+ + NF T + + P + Sbjct: 16 PRGSHMRILITGGAGCLGSNLIEHWLPQGHEILVID----NFATGKREVL---PPVAGLS 68 Query: 84 LMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTAD---VVATGALRL 140 +++ +TDA L R D KP V + AA +++ PD A+ G++ + Sbjct: 69 VIE---GSVTDAGLLERAFDSFKPTHVVHSAA------AYKDPDDWAEDAATNVQGSINV 119 Query: 141 LEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYR 200 +A + R + + A + P P +P P + Y SK A Sbjct: 120 AKAASKAGVK--RLLNFQTALCYGRPATVPIPID--SPTAPFTSYGISKTAG-------- 167 Query: 201 EAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGD 260 EA+ + + ++ + G I R+K G K F + RD+ D Sbjct: 168 EAFLMMSDVPVVSLRLANVTGPRLAIGPIPTFYKRLKAG--QKCFCSD--TVRDFLDMSD 223 Query: 261 YVEAMWLMLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVD 319 ++ L LQ+ +P + V+T EGH+++E DV Y+G + V + +V Sbjct: 224 FLAIADLSLQEGRPTGVFNVSTGEGHSIKEVFDVVLDYVGATLAEPVPVVAP--GADDVP 281 Query: 320 NLQGDASKAKEVLGWKPQVGFEKLVKMMVDED 351 ++ D SK + GWK +V F+ + + Sbjct: 282 SVVLDPSKTETEFGWKAKVDFKDTITGQLAWY 313 >2C20-A nrPDB Length = 330 Score = 240 bits (611), Expect = 1e-63, Method: Composition-based stats. Identities = 79/357 (22%), Positives = 131/357 (36%), Gaps = 45/357 (12%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 LI G G GS+ + L+ +G V + + + K + Sbjct: 2 NSILICGGAGYIGSHAVKKLVDEGLSVVVVDN------------LQTGHEDAITEGAKFY 49 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 DL D + LR + V + AA S V VS E P + GAL LLE + Sbjct: 50 NGDLRDKAFLRDVFTQENIEAVMHFAADSLVGVSMEKPLQYYNNNVYGALCLLEVMDEFK 109 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPP-QSETTPFHPRSPYAASKCAA----HWYTVNYREAY 203 +D K+ + ++ +G +E T +P + Y +K A HWY+ Y Sbjct: 110 VD-----KFIFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQASNLRY 164 Query: 204 GLFACNGILFNHESPRRGENFVTRK-ITRALGRIKVGLQTKLFL-------GNLQASRDW 255 +F + + GE+ + + ++ +G + K+ + + RD+ Sbjct: 165 KIFRYFNVAGATPNGIIGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDY 224 Query: 256 GFAGDYVEAMWLMLQ----QEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQR 311 D V A +L L+ + D Y + G +V+E +D N + E+ R Sbjct: 225 IHVEDLVAAHFLGLKDLQNGGESDFYNLGNGNGFSVKEIVDAVREVT--NHEIPAEVAPR 282 Query: 312 YFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLVDAGYMD 368 R + L + KAKE LGW P+ K + +E A GY Sbjct: 283 --RAGDPARLVASSQKAKEKLGWDPRYVNVKTI-------IEHAWNWHQKQPNGYEK 330 >1RKX-A nrPDB Length = 357 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 87/374 (23%), Positives = 137/374 (36%), Gaps = 58/374 (15%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRS----SNFNTQRINHIYIDPHNVNKAL 84 K +TG TG G +L+ +L G V G + S F T R+ Sbjct: 10 KRVFVTGHTGFKGGWLSLWLQTMGATVKGYSLTAPTVPSLFETARVAD-----------G 58 Query: 85 MKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAV 144 M+ D+ D + L I +P+ V+++AAQ V +S+ P T G + LLEA+ Sbjct: 59 MQSEIGDIRDQNKLLESIREFQPEIVFHMAAQPLVRLSYSEPVETYSTNVMGTVYLLEAI 118 Query: 145 RSHT----IDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYR 200 R + + + K Y ++G E PY+ SK A T +YR Sbjct: 119 RHVGGVKAVVNITSDKCYD-NKEWIWG-----YRENEAMGGYDPYSNSKGCAELVTSSYR 172 Query: 201 EAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL------QTKLFLGNLQASRD 254 ++ A G + R N + AL RI + + + N A R Sbjct: 173 NSFFNPANYGQHGTAVATVRAGNVIGGG-DWALDRIVPDILRAFEQSQPVIIRNPHAIRP 231 Query: 255 WGFAGDYVEAMWLMLQQE-------------KPDDYVVATEEGHTVEEFLDVSFGYLGLN 301 W + + L+ Q+ P+D AT + VE+ V + G + Sbjct: 232 WQHVLEPLSGYLLLAQKLYTDGAEYAEGWNFGPND-ADATPVKNIVEQM--VKYWGEGAS 288 Query: 302 WKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAK----- 356 W ++D P E L+ D SKAK LGW P+ ++ +V Sbjct: 289 W----QLDGN-AHPHEAHYLKLDCSKAKMQLGWHPRWNLNTTLEYIVGWHKNWLSGTDMH 343 Query: 357 REKVLVDAGYMDAK 370 + YM+ K Sbjct: 344 EYSITEINNYMNTK 357 >1WVG-A nrPDB Length = 359 Score = 231 bits (589), Expect = 4e-61, Method: Composition-based stats. Identities = 76/353 (21%), Positives = 130/353 (36%), Gaps = 37/353 (10%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRS----SNFNTQRINHIYIDPHNVNKAL 84 K +TG TG GS+L+ +L G V G + S F R+N + Sbjct: 10 KRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIVRLNDL----------- 58 Query: 85 MKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAV 144 M+ H D+ D LR I KP+ V+++AAQ V +S+E P T G + LLE V Sbjct: 59 MESHIGDIRDFEKLRSSIAEFKPEIVFHMAAQPLVRLSYEQPIKTYSTNVMGTVHLLETV 118 Query: 145 RSHT----IDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYR 200 + + + + K Y ++G E P PY+ SK A +R Sbjct: 119 KQVGNIKAVVNITSDKCYD-NREWVWG-----YRENEPMGGYDPYSNSKGCAELVASAFR 172 Query: 201 EAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL------QTKLFLGNLQASRD 254 ++ A + R N + A R+ + ++ + N + R Sbjct: 173 NSFFNPANYEQHGVGLASVRAGNVIGGG-DWAKDRLIPDILRSFENNQQVIIRNPYSIRP 231 Query: 255 WGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEF----LDVSFGYLGLNWKDYVE-ID 309 W + + ++ Q+ + + + ++ + W D + Sbjct: 232 WQHVLEPLSGYIVVAQRLYTEGAKFSEGWNFGPRDEDAKTVEFIVDKMVTLWGDDASWLL 291 Query: 310 QRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLV 362 P E L+ D SKA LGW P+ G + + +V + E +L+ Sbjct: 292 DGENHPHEAHYLKLDCSKANMQLGWHPRWGLTETLSRIVKWHKAWIRGEDMLI 344 >2Q1W-A nrPDB Length = 333 Score = 227 bits (577), Expect = 9e-60, Method: Composition-based stats. Identities = 70/328 (21%), Positives = 124/328 (37%), Gaps = 53/328 (16%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K ITGI GQ GS++ E LL +G +V G+ NF T R H+ P+ + Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGID----NFATGRREHLKDHPN------LTFV 71 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTAD---VVATGALRLLEAVR 145 + D + + + I ++PD V + AA S++ PD + G +++A + Sbjct: 72 EGSIADHALVNQLIGDLQPDAVVHTAA------SYKDPDDWYNDTLTNCVGGSNVVQAAK 125 Query: 146 SHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGL 205 + + ++ ++ +G P Q HPR+P +S + +Y E GL Sbjct: 126 KNNV-----GRFVYFQTALCYG-VKPIQQPVRLDHPRNPANSSYAISKSANEDYLEYSGL 179 Query: 206 FACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNL---------QASRDWG 256 +FVT ++ +G V +F L +A RD+ Sbjct: 180 -----------------DFVTFRLANVVGPRNVSGPLPIFFQRLSEGKKCFVTKARRDFV 222 Query: 257 FAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPA 316 F D A + Y ++ ++E D + L Y E + R P Sbjct: 223 FVKDLARATVRAVDGVGHGAYHFSSGTDVAIKELYDAVVEAMAL--PSYPEPEIRELGPD 280 Query: 317 EVDNLQGDASKAKEVLGWKPQVGFEKLV 344 + ++ D S+ + G ++ V Sbjct: 281 DAPSILLDPSRTIQDFGKIEFTPLKETV 308 >1GY8-A nrPDB Length = 397 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 87/400 (21%), Positives = 137/400 (34%), Gaps = 76/400 (19%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNK------- 82 L+ G G GS+ LL ++ + + +H+ + K Sbjct: 4 RVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTH-GKSDHVETRENVARKLQQSDGP 62 Query: 83 ------ALMKLHYADLTDASSLRRWIDVIKP-DEVYNLAAQSHVAVSFEIPDYTADVVAT 135 L D+ + L P D V ++ A V S P D Sbjct: 63 KPPWADRYAALEVGDVRNEDFLNGVFTRHGPIDAVVHMCAFLAVGESVRDPLKYYDNNVV 122 Query: 136 GALRLLEAVRSHTIDSGRTVKYYQAGSSEMFG--------STPPPQSETTPFHPRSPYAA 187 G LRLL+A+ H D K + S+ +FG + P P SPY Sbjct: 123 GILRLLQAMLLHKCD-----KIIFSSSAAIFGNPTMGSVSTNAEPIDINAKKSPESPYGE 177 Query: 188 SKCAAHWYTVNYREAYGLFACNGILFN----HESPRRGENF--VTRKITRALGRIK---- 237 SK A + EAYG+ FN HE GE++ T I LGR+ Sbjct: 178 SKLIAERMIRDCAEAYGIKGICLRYFNACGAHEDGDIGEHYQGSTHLIPIILGRVMSDIA 237 Query: 238 ------------VGLQTKLF-----LGNLQASRDWGFAGDYVEAMWLML---QQEKPDD- 276 + +F + RD+ D A L L ++ P+D Sbjct: 238 PDQRLTIHEDASTDKRMPIFGTDYPTPDGTCVRDYVHVCDLASAHILALDYVEKLGPNDK 297 Query: 277 ------YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDASKAKE 330 + + T G++V E ++V+ G + E +R PA L + KA+E Sbjct: 298 SKYFSVFNLGTSRGYSVREVIEVARKTTG-HPIPVRECGRREGDPA---YLVAASDKARE 353 Query: 331 VLGWKPQVGFEKLVKMMVDEDLELAKREKVLVDAGYMDAK 370 VLGWKP+ ++ +E + + + GY + Sbjct: 354 VLGWKPKYD-------TLEAIMETSWKFQRTHPNGYASQE 386 >1UDA-A nrPDB Length = 338 Score = 213 bits (542), Expect = 9e-56, Method: Composition-based stats. Identities = 70/359 (19%), Positives = 123/359 (34%), Gaps = 42/359 (11%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 L+TG +G GS+ LL G++V L + + Sbjct: 2 RVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLC-----NSKRSVLPVIERLGGKHPTFVE 56 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 D+ + + + + D V + A V S + P D G LRL+ A+R+ + Sbjct: 57 GDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVNGTLRLISAMRAANV 116 Query: 150 DSGRTVKYYQAGSSEMFGSTPP-PQSETTPFH-PRSPYAASKCAAHWYTVNYREAY---- 203 + + S+ ++G P P E+ P P+SPY SK + ++A Sbjct: 117 K-----NFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSKLMVEQILTDLQKAQPDWS 171 Query: 204 -GLFACNGILFNHESPRRGEN--FVTRKITRALGRIKVGLQTKL-FLGNLQASRDWGFAG 259 L + H S GE+ + + + ++ VG + L GN + D Sbjct: 172 IALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIFGNDYPTEDGTGVR 231 Query: 260 DYVEAMWLMLQQEKPDD----------YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEID 309 DY+ M L + Y + G++V + ++ G Sbjct: 232 DYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVNAFSKACGK--PVNYHFA 289 Query: 310 QRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLVDAGYMD 368 R R ++ DASKA L W+ +++ + D + GY D Sbjct: 290 PR--REGDLPAYWADASKADRELNWRVTRTLDEMAQ-----DTWHWQSRH---PQGYPD 338 >1I3M-A nrPDB Length = 348 Score = 207 bits (526), Expect = 8e-54, Method: Composition-based stats. Identities = 69/353 (19%), Positives = 126/353 (35%), Gaps = 35/353 (9%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNF-NTQRINHIYIDPHNVNKALMKLH 88 L+TG G GS+ LL GY + + F + + ++ Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 D+ D +L+R V + A + S + P V TG ++LLE +++H Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLKAMGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123 Query: 149 IDSGRTVKYYQAGSSEMFGSTP-PPQSETTPFHP-RSPYAASKCAAHWYTVNYREAYG-- 204 + + S+ ++G+ P E P +PY SK + +A Sbjct: 124 VK-----NLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTW 178 Query: 205 ---LFACNGILFNHESPRRGEN--FVTRKITRALGRIKVGLQTKL-FLGNLQA------S 252 L H S GE+ + + + ++ +G + L GN Sbjct: 179 NVVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGV 238 Query: 253 RDWGFAGDYVEAMWLMLQQEKPD----DYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEI 308 RD+ D + L++ K Y + T G++V + + G K ++ Sbjct: 239 RDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGK--KIPYKV 296 Query: 309 DQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVL 361 R R +V + S A+E LGW +G +++ EDL +++ Sbjct: 297 VAR--REGDVAACYANPSLAQEELGWTAALGLDRMC-----EDLWRWQKQNPS 342 >4WOK-A nrPDB Length = 336 Score = 191 bits (486), Expect = 3e-49, Method: Composition-based stats. Identities = 69/335 (20%), Positives = 106/335 (31%), Gaps = 40/335 (11%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 L+ G G GS+ + L G+GY S+ H Sbjct: 12 NNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLST-------------GHQSAVRWGDFV 58 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 D+ D + L ++ P V + AA ++V S E P G LL+A R Sbjct: 59 EGDILDQARLVETMEKYAPVAVIHFAASAYVGESVEDPAKYYRNNVGGTQSLLDACR--- 115 Query: 149 IDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 RT + S +G P E +P +PY +K A +Y AYGL Sbjct: 116 --LTRTQNVIFSSSCATYGVPSRLPIGEGEAQNPINPYGRTKLIAEHMLADYAVAYGLRY 173 Query: 208 CNGILFNHESPRRGENF------VTRKITRALGRIKVGLQTKLFLG------NLQASRDW 255 FN T I RA+ L G + RD+ Sbjct: 174 VALRYFNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYETPDGTCIRDY 233 Query: 256 GFAGDYVEAMWLMLQQ----EKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQR 311 D A L ++ + T G ++ E + G + V + R Sbjct: 234 IHVTDLARAHVLAVEHLKEAGGNLAVNLGTGRGTSIREIVQSIGRLTGRS----VPVAMR 289 Query: 312 YFRPAEVDNLQGDASKAKEVLGWKPQVG-FEKLVK 345 R + L D + A E LG+ + +++ Sbjct: 290 ARRAGDPPALYADPALAAEKLGFHTVYSDLDTIIR 324 >3ENK-A nrPDB Length = 341 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 72/353 (20%), Positives = 117/353 (33%), Gaps = 40/353 (11%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 + L+TG G GS+ LL GY+V + N + I I + Sbjct: 5 KGTILVTGGAGYIGSHTAVELLAHGYDVV-IADNLVNSKREAIARIEK----ITGKTPAF 59 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 H D++D +L R D + AA V S P L LL +R Sbjct: 60 HETDVSDERALARIFDAHPITAAIHFAALKAVGESVAKPIEYYRNNLDSLLSLLRVMRER 119 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPP--PQSETTPFHPRSPYAASKCAAHWYTVNYREA--- 202 + + + S+ ++G P P ET P +PY +K A + A Sbjct: 120 AVK-----RIVFSSSATVYG-VPERSPIDETFPLSATNPYGQTKLMAEQILRDVEAADPS 173 Query: 203 --YGLFACNGILFNHESPRRGEN--FVTRKITRALGRIKVGLQTKLFL-------GNLQA 251 + HES GE+ + + + ++ VG KL + + Sbjct: 174 WRVATLRYFNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTG 233 Query: 252 SRDWGFAGDYVEAMWLMLQQEKPDD----YVVATEEGHTVEEFLDVSFGYLGLNWKDYVE 307 RD+ D L + D + T G++V E + G E Sbjct: 234 VRDYIHVVDLARGHIAALDALERRDASLTVNLGTGRGYSVLEVVRAFEKASGR--AVPYE 291 Query: 308 IDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKV 360 + R RP +V + + A E +GWK + E++ D + Sbjct: 292 LVAR--RPGDVAECYANPAAAAETIGWKAERDLERMC-----ADHWRWQENNP 337 >6BWL-A nrPDB Length = 328 Score = 173 bits (439), Expect = 8e-44, Method: Composition-based stats. Identities = 69/339 (20%), Positives = 129/339 (38%), Gaps = 26/339 (7%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 L+TG G G ++ + LL +EV ++ +N T I + L + Sbjct: 2 KILVTGGAGFIGRWVVKRLLQDKHEVW-ILDNLANSTTANITEFA-----HDLNLKQCIQ 55 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 D+ D + + + D Y+LAA +V S + T + G LLE ++ + Sbjct: 56 GDIKDKKLVAQLFENNSFDLCYHLAASINVQDSIDDARATFENDTIGTFNLLEQCLNYDV 115 Query: 150 DSGRTVKYYQAGSSEMFGSTPP--PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 K + ++ SE P P SPYA SK AA ++Y AY L Sbjct: 116 ------KMVFMSTCMVYDKATNIQGISELDPIKPASPYAGSKIAAENMVLSYYYAYKLPV 169 Query: 208 CNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL 267 FN P + + + + ++ G+ + +RD + D + + Sbjct: 170 VVIRPFNTYGPFQKTGGEGGVVAIFINNKLDNVPLNIY-GDGKQTRDLLYVEDCADFVVA 228 Query: 268 MLQQEKPDDY--VVATEEGHTVEEFLDVSFG-YLGLNWKDYVEIDQRYFRPAEVDNLQGD 324 K + + T + ++ + ++ G + + ++ +E+ L + Sbjct: 229 AGYSAKANGHIINAGTGQDISINKLAELISGNKVSIQHVTHIHPQ------SEIQKLLCN 282 Query: 325 ASKAKEVLGWKPQVGFEKLVKMMVDE--DLELAKREKVL 361 KAK +L W+P+V E V + L++ +EK L Sbjct: 283 YEKAKTILNWEPKVSLEDGVIKTEEWIKSLKINPKEKEL 321 >2Q1T-A nrPDB Length = 377 Score = 144 bits (362), Expect = 7e-35, Method: Composition-based stats. Identities = 65/337 (19%), Positives = 110/337 (32%), Gaps = 33/337 (9%) Query: 30 IALITGITGQDGSYLTEFLLGKGY-EVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 ++ G G GS L + LL G +VH + S + + ++ Sbjct: 34 NVMVVGGAGFVGSNLVKRLLELGVNQVHVVDNLLS----------AEKINVPDHPAVRFS 83 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 +TD + L D D V++LA S P + L+L E ++ Sbjct: 84 ETSITDDALLASLQDEY--DYVFHLATYHGNQSSIHDPLADHENNTLTTLKLYERLKHFK 141 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPR---SPYAASKCAAHWYTVNYREAYGL 205 +E ET SPY+ SK +Y+V Y + + L Sbjct: 142 RLKKVVYSAAGCSIAEKTFDDAKATEETDIVSLHNNDSPYSMSKIFGEFYSVYYHKQHQL 201 Query: 206 FACNGILFNHESP---------RRGENFVTRKITRALGRIKV-GLQTKLFLGNLQASRDW 255 N P R V R +T + G+ L G A+RD+ Sbjct: 202 PTVRARFQNVYGPGEILGAGRWRGTPATVWRNVTPTFIYKALKGMPLPLENG-GVATRDF 260 Query: 256 GFAGDYVEAMWLMLQQEKPDD-YVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFR 314 F D + P Y +A+ + ++ + G N E+D+ R Sbjct: 261 IFVEDVANGLIACAADGTPGGVYNIASGKETSIADLATKINEITGNN----TELDRLPKR 316 Query: 315 PAEVD-NLQGDASKAKEVLGWKPQVGFEKLVKMMVDE 350 P + G KA+ LG+ V + ++ ++ Sbjct: 317 PWDNSGKRFGSPEKARRELGFSADVSIDDGLRKTIEW 353 >3SXP-A nrPDB Length = 362 Score = 135 bits (340), Expect = 2e-32, Method: Composition-based stats. Identities = 61/323 (18%), Positives = 107/323 (33%), Gaps = 18/323 (5%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNT-QRINHIYIDPHNVNKALMKL 87 + LITG G GS L + ++ NT N H N K Sbjct: 11 QTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIGFKG 70 Query: 88 HY--ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVR 145 AD+ + LRR + + D +++ AA S + + L LLE R Sbjct: 71 EVIAADINNPLDLRRL-EKLHFDYLFHQAAVS--DTTMLNQELVMKTNYQAFLNLLEIAR 127 Query: 146 SHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGL 205 + K A S+ ++G+T P P + Y SK + +++ Sbjct: 128 ------SKKAKVIYASSAGVYGNTKAPNVVGKNESPENVYGFSKLCMDEFVLSHSN--DN 179 Query: 206 FACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAM 265 FN PR T + L + + + RD+ + D ++A Sbjct: 180 VQVGLRYFNVYGPREFYKEKTASMVLQLALGAMAFKEVKLFEFGEQLRDFVYIEDVIQAN 239 Query: 266 WLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDA 325 ++ +K Y V + + E + + +LG Y++ +F + Q Sbjct: 240 VKAMKAQKSGVYNVGYSQARSYNEIVSILKEHLGDFKVTYIKNPYAFF----QKHTQAHI 295 Query: 326 SKAKEVLGWKPQVGFEKLVKMMV 348 L + P E +K + Sbjct: 296 EPTILDLDYTPLYDLESGIKDYL 318 >2C54-A nrPDB Length = 379 Score = 111 bits (278), Expect = 4e-25, Method: Composition-based stats. Identities = 57/339 (16%), Positives = 116/339 (34%), Gaps = 38/339 (11%) Query: 33 ITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYADL 92 ITG G S++ L +G+ V + + ++ + H DL Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVI---------ASDWKKNEHMTEDMFCD---EFHLVDL 81 Query: 93 TDASSLRRWIDVIKPDEVYNLAAQ-SHVAVSFEIPDYTADVVATGALRLLEAVRSHTIDS 151 + + + + D V+NLAA + + ++EA R + I Sbjct: 82 RVMENCLKVTEGV--DHVFNLAADMGGMGFIQSNHSVIMYNNTMISFNMIEAARINGIK- 138 Query: 152 GRTVKYYQAGSSEMFGSTPPPQSETT----------PFHPRSPYAASKCAAHWYTVNYRE 201 +++ A S+ ++ Q ETT P P+ Y + A +Y + Sbjct: 139 ----RFFYASSACIYPEFK--QLETTNVSLKESDAWPAEPQDAYGLERLATEELCKHYNK 192 Query: 202 AYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKL-FLGNLQASRDWGFAGD 260 +G+ G N P K A R + G+ +R + F + Sbjct: 193 DFGIECRIGRFHNIYGPFGTWKGGREKAPAAFCRKAQTSTDRFEMWGDGLQTRSFTFIDE 252 Query: 261 YVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDN 320 VE + + + + + + ++E ++ E ++ + + R Sbjct: 253 CVEGVLRLTKSDFREPVNIGSDEMVSMNEMAEMVLSFEEKKLPIHHIPGPEGVRGRN--- 309 Query: 321 LQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREK 359 D + KE LGW P + ++ +++ E ++EK Sbjct: 310 --SDNNLIKEKLGWAPNMRLKEGLRITYFWIKEQIEKEK 346 >1EQ2-A nrPDB Length = 310 Score = 105 bits (262), Expect = 3e-23, Method: Composition-based stats. Identities = 55/328 (16%), Positives = 101/328 (30%), Gaps = 32/328 (9%) Query: 31 ALITGITGQDGSYLTEFLLGKGY-EVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 ++TG G GS + + L KG ++ + + + L+ Sbjct: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNL--------------VDLNI 47 Query: 90 ADLTDASS-LRRWIDVI---KPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVR 145 AD D L + + + +++ A S ++ Y D + LL Sbjct: 48 ADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTE-WDGK-YMMDNNYQYSKELLHYCL 105 Query: 146 SHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH-PRSPYAASKCAAHWYTVNYREAYG 204 R + + A S+ +G E+ + P + Y SK Y Sbjct: 106 E------REIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEAN 159 Query: 205 LFACNGILFNHESPRRGENFVTRKITRAL-GRIKVGLQTKLFLGNLQASRDWGFAGDYVE 263 FN PR G + L ++ G KLF G+ RD+ + GD + Sbjct: 160 SQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVAD 219 Query: 264 AMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQG 323 L+ + + T + + D + Y +Y+ + Q Sbjct: 220 VNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPF-PDKLKGRYQAFTQA 278 Query: 324 DASKAKEVLGW-KPQVGFEKLVKMMVDE 350 D + G+ KP + V + Sbjct: 279 DLTNL-RAAGYDKPFKTVAEGVTEYMAW 305 >2X86-A nrPDB Length = 357 Score = 102 bits (255), Expect = 2e-22, Method: Composition-based stats. Identities = 54/330 (16%), Positives = 103/330 (31%), Gaps = 32/330 (9%) Query: 29 KIALITGITGQDGSYLTEFLLGKGY-EVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 ++ ++TG G GS + + L KG ++ + + + L Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNL--------------VDL 92 Query: 88 HYADLTDASS-LRRWIDVI---KPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEA 143 + AD D L + + + +++ A S ++ Y D + LL Sbjct: 93 NIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTE-WDGK-YMMDNNYQYSKELLHY 150 Query: 144 VRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH-PRSPYAASKCAAHWYTVNYREA 202 R + + A S+ +G E+ + P + + SK Y Sbjct: 151 CLE------REIPFLYASSAATYGGRTSDFIESREYEKPLNVFGYSKFLFDEYVRQILPE 204 Query: 203 YGLFACNGILFNHESPRRGENFVTRKITRAL-GRIKVGLQTKLFLGNLQASRDWGFAGDY 261 FN PR G + L ++ G KLF G+ RD+ + GD Sbjct: 205 ANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDV 264 Query: 262 VEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNL 321 + L+ + + T + + D + Y +Y+ + Sbjct: 265 ADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPF-PDKLKGRYQAFT 323 Query: 322 QGDASKAKEVLGW-KPQVGFEKLVKMMVDE 350 Q D + G+ KP + V + Sbjct: 324 QADLTNL-RAAGYDKPFKTVAEGVTEYMAW 352 >4WKG-A nrPDB Length = 660 Score = 101 bits (252), Expect = 4e-22, Method: Composition-based stats. Identities = 74/377 (19%), Positives = 126/377 (33%), Gaps = 56/377 (14%) Query: 7 GSRSDSESITAPKADSTVVEPRKIALITGITGQDGSYLTEFLL-GKGYEVHGLIRRSSNF 65 GSR +S+ + R LI G+ G G++LTE LL YEV+GL Sbjct: 301 GSRLNSQP-------ACTARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDI----- 348 Query: 66 NTQRINHIYIDPHNVNKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEI 125 + I+ PH D++ S V K D V L A + Sbjct: 349 GSDAISRFLNHPH------FHFVEGDISIHSEWIE-YHVKKCDVVLPLVAIATPIEYTRN 401 Query: 126 PDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH----- 180 P ++ LR++ + + +SE++G + + Sbjct: 402 PLRVFELDFEENLRIIRYCVKY------RKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGP 455 Query: 181 ---PRSPYAASKCAAHWYTVNYREAYGLFACNGILFNHESPR-----RGENFVTRKITRA 232 PR Y+ SK Y E GL FN PR +R IT+ Sbjct: 456 VNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQL 515 Query: 233 LGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWLMLQQEK----PDDYVVATEEGH-TV 287 + + G KL G + R + D +EA++ +++ + + E ++ Sbjct: 516 ILNLVEGSPIKLIDG-GKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASI 574 Query: 288 EEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQG-----------DASKAKEVLGWKP 336 EE ++ + + FR E + G A L W+P Sbjct: 575 EELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNAHRCLDWEP 634 Query: 337 QVGFEKLVKMMVDEDLE 353 ++ ++ + +D L Sbjct: 635 KIDMQETIDETLDFFLR 651 >3M2P-A nrPDB Length = 311 Score = 95.3 bits (235), Expect = 4e-20, Method: Composition-based stats. Identities = 65/317 (20%), Positives = 102/317 (32%), Gaps = 36/317 (11%) Query: 33 ITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYADL 92 +TG TG G Y+ E + G L R N + +D Sbjct: 7 VTGGTGFLGQYVVESIKNDGNTPIILTRSIGNKAIN---------------DYEYRVSDY 51 Query: 93 TDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTIDSG 152 T + + D D V +LAA + L +A + I Sbjct: 52 TLEDLINQLND---VDAVVHLAA----TRGSQGKISEFHDNEILTQNLYDACYENNIS-- 102 Query: 153 RTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFACNGI 211 A + + P +E P Y SK A Y GL N Sbjct: 103 ---NIVYASTISAYSDETSLPWNEKELPLPDLMYGVSKLACEHIGNIYSRKKGLCIKNLR 159 Query: 212 LFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWLMLQQ 271 F H +N I R + G Q L N A R++ +A D +++ L+Q Sbjct: 160 -FAHLYGFNEKN--NYMINRFFRQAFHGEQLTLH-ANSVAKREFLYAKDAAKSVIYALKQ 215 Query: 272 EK-PDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDASKAKE 330 EK + + + + T E + G KD + + + + D+SKAKE Sbjct: 216 EKVSGTFNIGSGDALTNYEVANTINNAFGN--KDNLLVKNPNANEG-IHSSYMDSSKAKE 272 Query: 331 VLGWKPQVGFEKLVKMM 347 +L + F V+ + Sbjct: 273 LLDFSTDYNFATAVEEI 289 >1GFS-A nrPDB Length = 321 Score = 94.1 bits (232), Expect = 8e-20, Method: Composition-based stats. Identities = 59/352 (16%), Positives = 107/352 (30%), Gaps = 58/352 (16%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 ++ I G G GS + L +G +V ++R N Sbjct: 3 KQRVFIAGHRGMVGSAIRRQLEQRG-DVELVLRTRDELN--------------------- 40 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQ-SHVAVSFEIPDYTADVVATGALRLLEAVRS 146 L D+ ++ + + D+VY AA+ + + P ++ A Sbjct: 41 ----LLDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQ 96 Query: 147 HTIDSGRTVKYYQAGSSEMFGSTPP-PQSETTPF----HPRS-PYAASKCAAHWYTVNYR 200 + ++ K GSS ++ P +E+ P + PYA +K A +Y Sbjct: 97 NDVN-----KLLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYN 151 Query: 201 EAYGLFACNGILFNHESP---RRGEN--FVTRKITRALGRIKVGLQTKLFLGNLQASRDW 255 YG + + N P N + + R + G+ R++ Sbjct: 152 RQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREF 211 Query: 256 GFAGDYVEA----------MWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDY 305 D A +WL Q V T T+ E +G + Sbjct: 212 LHVDDMAAASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGR-- 269 Query: 306 VEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKR 357 + +P D ++ + LGW ++ E + LE R Sbjct: 270 --VVFDASKPDGTPRKLLDVTRLHQ-LGWYHEISLEAGLASTYQWFLENQDR 318 >3WMX-A nrPDB Length = 358 Score = 87.2 bits (214), Expect = 1e-17, Method: Composition-based stats. Identities = 66/331 (19%), Positives = 108/331 (32%), Gaps = 36/331 (10%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKA-LMKLH 88 LI G GQ GS L L + R N I D + + Sbjct: 27 KILIVGANGQIGSELALALAER---------------YGRTNVITSDVVPTGRHVHLTHE 71 Query: 89 YADLTDASSLRRWIDVIKPDEVYNL-AAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 + TD L ++ +VY L AA S + P + ++ T L +LE R Sbjct: 72 MLNATDRGELATVVERHGITQVYLLAAALSATGE--KAPQWAWNLNMTSLLNVLELARQT 129 Query: 148 TIDSGRTVKYYQAGSSEMFG-STPPPQSE-TTPFHPRSPYAASKCAAHWYTVNYREAYGL 205 ++ + + S FG +TP Q+ T P + Y SK A + Y +G+ Sbjct: 130 GLE-----RVFWPSSIAAFGPTTPAGQTPQKTVMEPTTVYGISKQAGEGWCRWYHANHGV 184 Query: 206 FACNGILFNHESPRRGENFVTRKIT-RALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEA 264 + S + T G FL +A + D + A Sbjct: 185 DVRSVRYPGLISHKTPPGGGTTDYAVDIFHAAVTGEPYTCFLKEDEAL-PMMYMPDAIRA 243 Query: 265 MWLMLQQE-----KPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVD 319 +++ + Y +A T + + ++ E D R Sbjct: 244 TIELMEAPADKLSERGSYNIA-GMSFTPAQIAAAIREQV-PGFQIRYEPDYRQAIAQGWP 301 Query: 320 NLQGDASKAKEVLGWKPQVGFEKLVKMMVDE 350 + D S A+ GWK Q G +++V M+ Sbjct: 302 D-SIDDSVARADWGWKAQYGLKEMVADMLAN 331 >4G5H-A nrPDB Length = 363 Score = 84.1 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 43/274 (15%), Positives = 79/274 (28%), Gaps = 34/274 (12%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 KI LITG TG G+ + + L + + R N + +K + Sbjct: 26 KILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDE-------KKQDDIRKKYNNSKLKFY 78 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 D+ D+ S+ + + D V++ AA V P G +L++ Sbjct: 79 IGDVRDSQSVETAMRDV--DYVFHAAALKQVPSCEFFPVEAVKTNIIGTENVLQSAIHQN 136 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFAC 208 + K + + +P + SK V + + Sbjct: 137 VK-----KVICLSTDK-------------AAYPINAMGISKAMMEKVFVAKSR--NIRSE 176 Query: 209 NG-ILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL 267 I I + +IK G L + + +R D VE + Sbjct: 177 QTLICGTRYGNVMASRGS--VIPLFIDKIKAG--EPLTITDPDMTRFLMSLEDAVELVVH 232 Query: 268 MLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLN 301 + + D +V TV + + Sbjct: 233 AFKHAETGDIMVQKAPSSTVGDLATALLELFEAD 266 >3SC6-A nrPDB Length = 287 Score = 83.7 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 49/297 (16%), Positives = 94/297 (31%), Gaps = 46/297 (15%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 ++ +ITG GQ G L E L + Y+++ ++ Sbjct: 5 KERVIITGANGQLGKQLQEELNPEEYDIYPFDKKLL------------------------ 40 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 D+T+ S +++ + I+P + + AA + V + + D + A GA + A + Sbjct: 41 ---DITNISQVQQVVQEIRPHIIIHCAAYTKVDQAEKERDLAYVINAIGARNVAVASQLV 97 Query: 148 TIDSGRTVKYYQAGSSEMF-GSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLF 206 K + +F G P E P + Y ASK A + Y + Sbjct: 98 G------AKLVYISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKELHNKYFIV 151 Query: 207 ACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMW 266 + + + G NFV I ++G + + + D + Sbjct: 152 RTSWLYGKY-----GNNFVKTMI-------RLGKEREEISVVADQIGSPTYVADLNVMIN 199 Query: 267 LMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQG 323 ++ Y V+ + EF F Y + + + A Sbjct: 200 KLIHTSLYGTYHVSNTGSCSWFEFAKKIFSYANMKVNVLPVSTEEFGAAAARPKYSI 256 >4EJ0-A nrPDB Length = 342 Score = 83.7 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 50/345 (14%), Positives = 94/345 (27%), Gaps = 45/345 (13%) Query: 30 IALITGITGQDGSYLTEFLLGKGY-EVHGLIRRSSNFNTQRINHIYIDPHNVNKALMK-L 87 ++TG G G+ L + L +G + + + + + ID + ++ Sbjct: 14 TLIVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERF 73 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 D K V++ A S + Y D + +L+A + Sbjct: 74 ARGDF------------GKVRAVFHEGACSDTMET--DGRYMMDNNFRYSRAVLDACLAQ 119 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFA 207 + A S+ ++G + E P + Y SK Sbjct: 120 GAQ------FLYASSAAIYGGSSRFVEEREVEAPLNVYGYSKFLFDQVIRRVMPGAKSQI 173 Query: 208 CNGILFNHESPRRGENFVTRKIT-RALGRIKVGLQTKLF-----LGNLQASRDWGFAGDY 261 FN PR + + + + KLF G + +RD+ D Sbjct: 174 AGFRYFNVYGPRESHKGRMASVAFHNFNQFRAEGKVKLFGEYSGYGPGEQTRDFVSVEDV 233 Query: 262 VEAMWLMLQQ-EKPDDYVVATEEGHTVEE----FLDVSFGYLGLNWKDYVE--------- 307 + EK + + T + ++ G E Sbjct: 234 AKVNLYFFDHPEKSGIFNLGTGRAQPFNDIAATVVNTLRALEGQPALTLAEQVEQGLVEY 293 Query: 308 -IDQRYFRPAEVDNLQGDASKAKEVLGWK-PQVGFEKLVKMMVDE 350 R Q D +K G+ P + ++ V V Sbjct: 294 VPFPDALRGKYQCFTQADQTKL-RAAGYDAPFLTVQEGVDRYVRW 337 >4KTT-E nrPDB Length = 327 Score = 83.0 bits (203), Expect = 2e-16, Method: Composition-based stats. Identities = 56/344 (16%), Positives = 96/344 (27%), Gaps = 42/344 (12%) Query: 27 PRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMK 86 P + L+TG TG G + + + G R + K Sbjct: 20 PNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRA--------------------RPK 59 Query: 87 LHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRS 146 +L D++++ I +P + + AA+ V PD + + + L + + Sbjct: 60 FEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAA 119 Query: 147 HTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLF 206 S +F T PP E P + Y +K + L Sbjct: 120 VGAF------LIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLEN----NLG 169 Query: 207 ACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVE--- 263 A + E +T +++ ++ + R D Sbjct: 170 AAVLRIPILYGEV--EKLEESAVTVMFDKVQFSNKSANM--DHWQQRFPTHVKDVATVCR 225 Query: 264 --AMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEI-DQRYFRPAEVDN 320 A ML + + E T E L I D N Sbjct: 226 QLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRN 285 Query: 321 LQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVLVDA 364 Q D SK + LG + F +K + + KR + V Sbjct: 286 AQLDCSKLET-LGIGQRTPFRIGIKESL-WPFLIDKRWRQTVFH 327 >2NNL-D nrPDB Length = 337 Score = 81.4 bits (199), Expect = 6e-16, Method: Composition-based stats. Identities = 58/334 (17%), Positives = 108/334 (32%), Gaps = 33/334 (9%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 + +TG +G GS+L LL +GY V +R + N +++ H+ P + + L Sbjct: 5 SETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPT--NVKKVKHLLDLPKA--ETHLTL 60 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 ADL D S I V+++A + FE D +V+ +L ++S Sbjct: 61 WKADLADEGSFDEAIKGC--TGVFHVA----TPMDFESKDPENEVIKPTIEGMLGIMKSC 114 Query: 148 TIDSGRTVKYYQAGSSE----------MFGSTPPPQSETTPFHPRSP--YAASKCAAHWY 195 + + S+ ++ + E + Y SK A Sbjct: 115 AA-AKTVRRLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKTLAEQA 173 Query: 196 TVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDW 255 Y + + I P + IT AL I + Q + Sbjct: 174 AWKYAKENNIDFITIIPTLVVGPFIMSSMPPSLIT-ALSPITGNEAHYSIIRQGQ----F 228 Query: 256 GFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRP 315 D A + + K + + + + + + + +Y I + Sbjct: 229 VHLDDLCNAHIYLFENPKAEGRYICSSHDCIILDLAKMLREK----YPEY-NIPTEFKGV 283 Query: 316 AEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVD 349 E +SK LG++ + E + VD Sbjct: 284 DENLKSVCFSSKKLTDLGFEFKYSLEDMFTGAVD 317 >5B6K-A nrPDB Length = 366 Score = 79.9 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 59/360 (16%), Positives = 122/360 (33%), Gaps = 46/360 (12%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 ++G TG ++ LL + Y+V G +R + + ++ + N ++K Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEK--GDHLKNVIFKGGDFNYEIVK--- 77 Query: 90 ADLTDASSLRRWIDVIKPDE--VYNLAAQSH-VAVSFEIPDYTADVVATGALRLLEAVRS 146 D++D ++ + D V + A+ H E V G +LE+++ Sbjct: 78 -DISDPTAFDHVFEKHGKDIKVVLHTASPFHFNTTDIEKDLLIPAVN--GTKGILESIKK 134 Query: 147 HTIDSGRTVKYYQA-----GSSEMFGSTPPPQS-----------ETTPFHPRSPYAASKC 190 + + V + + +MF + ++ E+ P Y SK Sbjct: 135 YAAQTVERVVVTSSFAANTSTVDMFYAKDSSKTITEESWNQDTWESCQSDPIRGYCGSKK 194 Query: 191 AAHWYTVNYREA------YGLFACNGILF----NHESPRRGENFVTRKITRALGRIKVGL 240 A ++ A + L N + N+ P + + ++ +L +K Sbjct: 195 FAEKAAWDFYNANKDSVKFKLSIINPVYVFGPQNYVEPGKKILNTSSEVINSLVHLKKDD 254 Query: 241 QTKLFLGNLQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEG-HTVEEFLDVSFGYLG 299 F G D +A L Q+++ + + G T + LD+ Sbjct: 255 PLPEFAG-GH-----IDVRDVAKAHILAFQKDELIEQRLMLHAGLFTTQTLLDIINEQFP 308 Query: 300 LNWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREK 359 P + D SK K++LG++ + +K + + + LE K Sbjct: 309 ELKGKIPAGKPGTGNPDDALTPV-DNSKTKKLLGFE-FIDLKKDLYDTISQILEAEKNSN 366 >4J2O-A nrPDB Length = 363 Score = 79.5 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 40/249 (16%), Positives = 73/249 (29%), Gaps = 34/249 (13%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+ LITG TG G+ + + L + + R + A +K + Sbjct: 24 KVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDE-------KKQDDMRKKYHSAKLKFY 76 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 D+ D +S+ + D +Y+ AA V P G +LEA + Sbjct: 77 IGDVRDYNSILNATRGV--DYIYHAAALKQVPSCEFHPMEAVKTNVLGTENVLEAAIQNH 134 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAY-GLFA 207 + + + + +P + SK V GL Sbjct: 135 VK-----RVVCLSTDK-------------AVYPINAMGISKAMMEKVMVAKSRNLEGLDT 176 Query: 208 CNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWL 267 I I + +I+ G L + + +R D V+ + Sbjct: 177 V--ICGTRYGNVMASRGS--VIPLFVDQIRQGK--PLTITDPNMTRFMMTLEDAVDLVLY 230 Query: 268 MLQQEKPDD 276 + + D Sbjct: 231 AFEHGENGD 239 >2P4H-X nrPDB Length = 322 Score = 76.4 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 60/333 (18%), Positives = 113/333 (33%), Gaps = 42/333 (12%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 + +TG TG GS++ + LL GY V+ IR ++ + ++ + Sbjct: 1 KGRVCVTGGTGFLGSWIIKSLLENGYSVNTTIRADPE---RKRDVSFLTNLPGASEKLHF 57 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 ADL++ S I+ +++ A+ AVS T GAL +L+A Sbjct: 58 FNADLSNPDSFAAAIEGCV--GIFHTASPIDFAVSEPEEIVTKRT-VDGALGILKAC--- 111 Query: 148 TIDSGRTVKYYQAGSSEMF---GSTPPPQSETT-----------PFHPRSPYAASKCAAH 193 ++S ++ S G E+ PF YA SK A Sbjct: 112 -VNSKTVKRFIYTSSGSAVSFNGKDKDVLDESDWSDVDLLRSVKPFGWN--YAVSKTLAE 168 Query: 194 WYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGR---IKVGLQTKLFLGNLQ 250 + + E G+ IL P FV K+ ++ + + +G + ++ + Sbjct: 169 KAVLEFGEQNGIDVVTLIL-----PFIVGRFVCPKLPDSIEKALVLVLGKKEQIGVTRFH 223 Query: 251 ASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQ 310 D A +L+ P + +EE + L + +Y + Sbjct: 224 MV----HVDDVARAHIYLLENSVPGGRYNCSPFIVPIEEMSQL----LSAKYPEYQILTV 275 Query: 311 RYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKL 343 + + L +K G+ + E + Sbjct: 276 DELKEIKGARLPDLNTKKLVDAGFDFKYTIEDM 308 >1VL0-A nrPDB Length = 292 Score = 75.3 bits (183), Expect = 5e-14, Method: Composition-based stats. Identities = 57/337 (16%), Positives = 104/337 (30%), Gaps = 73/337 (21%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 LITG GQ G + + L GK EV + Sbjct: 14 KILITGANGQLGREIQKQLKGKNVEVIPTD---------------------------VQD 46 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 D+T+ ++ ++ + KP+ V N AA + V E D + A G L A S Sbjct: 47 LDITNVLAVNKFFNEKKPNVVINCAAHTAVDKCEEQYDLAYKINAIGPKNLAAAAYSVGA 106 Query: 150 DSGRTVKYYQAGSSEMF-GSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFAC 208 + Q + +F G P +E +P+S Y +K + Y + Sbjct: 107 E------IVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKALNPKYYIVRT 160 Query: 209 NGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAG----DYVEA 264 + + G NFV I +G L+ D D Sbjct: 161 AWLYGD------GNNFVKTMI-------NLGK----THDELKVVHDQVGTPTSTVDLARV 203 Query: 265 MWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGD 324 + ++ ++ + + + +F F G++ K + + RPA+ Sbjct: 204 VLKVIDEKNYGTFHCTCKGICSWYDFAVEIFRLTGIDVKVTPCTTEEFPRPAK------- 256 Query: 325 ASKAKEVLGWKPQVG-FEKLVKMMVDEDLELAKREKV 360 +P+ + + D+ +E + Sbjct: 257 ----------RPKYSVLRNYMLELTTGDITREWKESL 283 >4BKP-A nrPDB Length = 336 Score = 73.7 bits (179), Expect = 1e-13, Method: Composition-based stats. Identities = 46/340 (13%), Positives = 100/340 (29%), Gaps = 50/340 (14%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 L+TG +G G + + + + + + Sbjct: 24 RILVTGGSGLVGKAIQK----------VVADGAGLPGEDWV-------------FVSSKD 60 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQ-SHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 ADLTD + R + ++P V +LAA + + + +L + Sbjct: 61 ADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSA--FE 118 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH--PRSP---YAASKCAAHWYTVNYREAY 203 + + + V + T P ET + P + Y+ +K Y + Y Sbjct: 119 VGARKVVSCL--STCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQY 176 Query: 204 GLFACNGILFNHESP-----RRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFA 258 G I N P + + I + G ++ G R + ++ Sbjct: 177 GCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVW-GTGNPRRQFIYS 235 Query: 259 GDYVEAMWLMLQ---QEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRP 315 D + +L+ + +P V E+ +++E + + + E+ + Sbjct: 236 LDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFH----GEVTFDTTKS 291 Query: 316 AEVDNLQGDASKAKE---VLGWKP-QVGFEKLVKMMVDED 351 SK + + P + ++ D Sbjct: 292 DGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDNY 331 >4WPG-A nrPDB Length = 289 Score = 72.9 bits (177), Expect = 2e-13, Method: Composition-based stats. Identities = 38/199 (19%), Positives = 68/199 (34%), Gaps = 42/199 (21%) Query: 31 ALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYA 90 LITG GQ G+ L L +G + + + Sbjct: 7 ILITGSNGQLGTELRYLLDERGVDYVAVD---------------------------VAEM 39 Query: 91 DLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTAD-VVATGALRLLEAVRSHTI 149 D+T+ + +KP VY+ AA + V + + + + TG+ + +A + Sbjct: 40 DITNEDKVEAVFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGA 99 Query: 150 DSGRTVKYYQAGSSEMF-GSTPPPQS--ETTPFHPRSPYAASKCAAHWYTVNYREAYGLF 206 + +F G+ P Q ET P++ Y +K Y E + + Sbjct: 100 T------LVYISTDYVFDGNKPVGQEWVETDHPDPKTEYGRTKRLGELAVERYAEHFYII 153 Query: 207 ACNGILFNHESPRRGENFV 225 + N+ G+NFV Sbjct: 154 RTAWVFGNY-----GKNFV 167 >2GN9-A nrPDB Length = 344 Score = 71.8 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 38/301 (12%), Positives = 86/301 (28%), Gaps = 44/301 (14%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 + LITG TG G +L ++ ++ + + + M+ Sbjct: 22 QTILITGGTGSFGKCFVRKVLDTTNAKKIIV-----YSRDELKQSEMAMEFNDPR-MRFF 75 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 D+ D L ++ + D + AA HV ++ P GA ++ A + Sbjct: 76 IGDVRDLERLNYALEGV--DICIHAAALKHVPIAEYNPLECIKTNIMGASNVINACLKNA 133 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWY---TVNYREAYGL 205 I + + + +P + Y A+K + N++ + Sbjct: 134 ISQVIAL-----STDK-------------AANPINLYGATKLCSDKLFVSANNFKGSSQT 175 Query: 206 FACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAM 265 N R + ++ +++ + +++ +R W + V + Sbjct: 176 QFSVVRYGNVVGSR-------GSVVPFFKKLVQNKASEIPITDIRMTRFWITLDEGVSFV 228 Query: 266 WLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDA 325 L++ V + + L RP E + Sbjct: 229 LKSLKRMH--------GGEIFVPKIPSMKMTDLAKALAPNTPTKIIGIRPGEKLHEVMIP 280 Query: 326 S 326 Sbjct: 281 K 281 >4R1T-A nrPDB Length = 337 Score = 71.0 bits (172), Expect = 8e-13, Method: Composition-based stats. Identities = 44/272 (16%), Positives = 82/272 (30%), Gaps = 41/272 (15%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 ++ +TG G S+L + LL KGY V G +R + + + + Sbjct: 11 QVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTLCK---- 66 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 ADL D SLR I+ D V++ A+ + P+ + G ++ A Sbjct: 67 -ADLLDYQSLREAINGC--DGVFHTASPV-----TDDPEQMVEPAVIGTKNVINAAAEAN 118 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPP----QSETTPFHP------RSPYAASKCAAHWYTVN 198 + + + ++ ET P ++ Y K A Sbjct: 119 VRRV----VFTSSIGAVYMDPNRDPETVVDETCWSDPDFCKNTKNWYCYGKMVAEQAAWE 174 Query: 199 YREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQA----SRD 254 + G+ V + + V K G+ + + Sbjct: 175 EAKEKGVDLVVIN----------PVLVQGPLLQTTVNASVLHILKYLTGSAKTYANSVQA 224 Query: 255 WGFAGDYVEAMWLMLQQEKP-DDYVVATEEGH 285 + D A L+ + + Y+ A H Sbjct: 225 YVDVKDVALAHILLYETPEASGRYLCAESVLH 256 >3HFS-A nrPDB Length = 338 Score = 66.4 bits (160), Expect = 2e-11, Method: Composition-based stats. Identities = 69/357 (19%), Positives = 115/357 (32%), Gaps = 52/357 (14%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 +K A + G TG S L + LL KGY V+ +R N ++++H+ + +K+ Sbjct: 9 KKTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPD--NQKKVSHLLELQELGD---LKI 63 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYT-ADVVATGALRLLEAVRS 146 ADLTD S I D V+++A H A E P+ G + +++A Sbjct: 64 FRADLTDELSFEAPIAGC--DFVFHVATPVHFAS--EDPENDMIKPAIQGVVNVMKACTR 119 Query: 147 HTI-------DSGRTVKYYQAGSSEMFGSTPPPQSET---TPFHPRSPYAASKCAAHWYT 196 S V Q + + + P Y ASK A Sbjct: 120 AKSVKRVILTSSAAAVTINQLDGTGLVVDEKNWTDIEFLTSAKPPTWGYPASKTLAEKAA 179 Query: 197 VNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGN-------- 248 + E + I + +T + ++ GL L GN Sbjct: 180 WKFAEENNIDLITVI-----PTLMAGSSLTSDVPSSI-----GLAMSLITGNEFLINGMK 229 Query: 249 ----LQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKD 304 L S D A + ++E + +V E + Sbjct: 230 GMQMLSGSVSIAHVEDVCRAHIFVAEKESASGRYICCAANTSVPELAKFLSK---RYPQY 286 Query: 305 YVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKREKVL 361 V D F P L + K + F+ ++ + DE +E K + +L Sbjct: 287 KVPTDFGDFPP--KSKLIISSEKLVKE-----GFSFKYGIEEIYDESVEYFKAKGLL 336 >3RFT-A nrPDB Length = 267 Score = 66.4 bits (160), Expect = 2e-11, Method: Composition-based stats. Identities = 39/188 (20%), Positives = 60/188 (31%), Gaps = 30/188 (15%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K L+TG GQ G + E L E+ L + P + + Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMA-EILRLAD--------------LSPLDPAGPNEECV 48 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIP-DYTADVVATGALRLLEAVRSH 147 DL DA+++ + D + +L +S E P + G L EA R+H Sbjct: 49 QCDLADANAVNAMVAGC--DGIVHLG-----GISVEKPFEQILQGNIIGLYNLYEAARAH 101 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPPPQS--ETTPFHPRSPYAASKCAAHWYTVNYREAYGL 205 + A S+ G P + P P Y SKC Y + +G Sbjct: 102 G-----QPRIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKCFGENLARMYFDKFGQ 156 Query: 206 FACNGILF 213 + Sbjct: 157 ETALVRIG 164 >2GGS-A nrPDB Length = 273 Score = 66.0 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 53/303 (17%), Positives = 94/303 (31%), Gaps = 45/303 (14%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 LITG +GQ G L+ L + +EV + S ++ Sbjct: 2 RTLITGASGQLGIELSRLLSER-HEVIKVYNSSEIQGGYKL------------------- 41 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 DLTD L +I +PD + N AA + V + + A ++ A + Sbjct: 42 -DLTDFPRLEDFIIKKRPDVIINAAAMTDVDKCEIEKEKAYKINAEAVRHIVRAGK---- 96 Query: 150 DSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFACN 209 + +F E +P + Y SK E + L + Sbjct: 97 --VIDSYIVHISTDYVFDGEKGNYKEEDIPNPINYYGLSKLLG--------ETFALQDDS 146 Query: 210 GILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEAMWLML 269 I+ S + + L K K + + A + A+ +L Sbjct: 147 LII--RTSGIFRNKGFPIYVYKTLKEGKTVFAFKGYYSPISARK-------LASAILELL 197 Query: 270 QQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDASKAK 329 + K VA E + E L + + R + + D+S+A+ Sbjct: 198 ELRKTGIIHVA-GERISRFELALKIKEKFNLPGEVKEVDEVRGWIAKRPYDSSLDSSRAR 256 Query: 330 EVL 332 ++L Sbjct: 257 KIL 259 >4R1U-A nrPDB Length = 349 Score = 64.9 bits (156), Expect = 6e-11, Method: Composition-based stats. Identities = 45/290 (15%), Positives = 87/290 (30%), Gaps = 40/290 (13%) Query: 22 STVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVN 81 S+V + +TG G S+L + LL +GY V G +R + + + Sbjct: 21 SSVSGGDQTVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELE-----GA 75 Query: 82 KALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLL 141 + + LH DL D S++ + V++ A+ + PD + G ++ Sbjct: 76 RERLTLHKVDLLDLQSIQSVVHGCH--GVFHTASPV-----TDNPDEMLEPAVNGTKNVI 128 Query: 142 EAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQS------------ETTPFHPRSPYAASK 189 A + + S P E + ++ Y K Sbjct: 129 IASAEAKVR-----RVVFTSSIGTVYMDPNTSRDVVVDESYWSDLEHCK-NTKNWYCYGK 182 Query: 190 CAAHWYTVNYREAYGLFACNGILFNHESPRRGE--NFVTRKITRALGRIKVGLQTKLFLG 247 A + + + P N T I + L K ++ Sbjct: 183 TVAEQSAWDIAKENQVDLVVVNPVVVLGPLLQPTINASTIHILKYLNGAA-----KTYV- 236 Query: 248 NLQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGY 297 A++ + D A L+ + + E E +++ Y Sbjct: 237 --NATQSYVHVKDVALAHLLVYETNSASGRYICCETALHRGEVVEILAKY 284 >4PVC-A nrPDB Length = 342 Score = 64.1 bits (154), Expect = 8e-11, Method: Composition-based stats. Identities = 51/357 (14%), Positives = 117/357 (32%), Gaps = 46/357 (12%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 ++G G ++ + LL + Y+V G R + ++ ++ N K M++ Sbjct: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSAR-----SQEKAENLTEAFGNNPKFSMEVVP 56 Query: 90 ADLTDASSLRRWIDVIKPD--EVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 D++ + D V + A+ ++ D G +L +++ + Sbjct: 57 -DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIP-AVNGVKGILHSIKKY 114 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPPPQS--------------ETTPFHPRSPYAASKCAAH 193 DS V + + +F E+ P + Y SK A Sbjct: 115 AADSVERV-VLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAE 173 Query: 194 WYTVNYRE------AYGLFACNGILFNHESPRRGENFVTR------KITRALGRIKVGLQ 241 + E + L A N + P+ + V + ++ +L + + Sbjct: 174 KAAWEFLEENRDSVKFELTAVNPVY--VFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDK 231 Query: 242 TKLFLGNLQASRDWGFAGDYVEAMWLMLQQEKP-DDYVVATEEGHTVEEFLDVSFGYLGL 300 G + D +A + Q+ + ++ +E T+++ LD+ + Sbjct: 232 IPELFGG------YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPV 285 Query: 301 NWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELAKR 357 + D K+K++LG+K + ++ + + L+ R Sbjct: 286 LKGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFR-NLKETIDDTASQILKFEGR 341 >6AQY-A nrPDB Length = 341 Score = 62.5 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 55/350 (15%), Positives = 102/350 (29%), Gaps = 63/350 (18%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 + L+TG TG G E ++ K + + Sbjct: 26 VILVTGGTGLFGKA-VEHIVKK------------------------EQIKGKWVFLGSKD 60 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEI---PDYTADVVATGALRLLEAVRS 146 DL DA + ++ + +P V +LAA V F+ +L Sbjct: 61 GDLRDADACKQPFEKYRPTYVIHLAA--FVGGLFKNMNFKVSFWLDNVNMNNNILTCCYD 118 Query: 147 HTIDSGRTVKYYQAGSSEMFGSTPPPQSETT-----PFHPRSPYAASKCAAHWYTVNYRE 201 + + + P +E P + YA +K Y E Sbjct: 119 FGVKKTISC----LSTCVFPDKIEYPITEEKLHEGPPHFSNNAYAYAKRMLDMLGRWYNE 174 Query: 202 AY---GLFACNGIL--FNHESPRRGENFVTRKITRALG----RIKVGLQTKLFLGNLQAS 252 G + N P N + L + + + G+ + Sbjct: 175 KAVNEGKSCLFTSVIPTNLFGPHDNFNVEAGHVLPGLMHKCYKAQQNGTDFVVFGSGKPL 234 Query: 253 RDWGFAGDYVEA-MWLML--QQEKPDDYVVATEEGHTVEEFLDVSFGY---LGLNWKDYV 306 R + ++ D +W M Q E+P V+ E+ ++ + G D Sbjct: 235 RQFLYSHDAARMLLWTMFNYQSEEPIMLCVSEEDEKSIGQVAQTIKDAFNFTGNMVFDTS 294 Query: 307 EIDQRYFR-PAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELA 355 + D +Y + + L+ + + + P FE+ +K V LE Sbjct: 295 KADGQYKKTSSNAKFLRLNPT-----FQYTP---FEQAIKETVQWFLENY 336 >5U9C-A nrPDB Length = 292 Score = 61.8 bits (148), Expect = 5e-10, Method: Composition-based stats. Identities = 34/172 (19%), Positives = 55/172 (31%), Gaps = 34/172 (19%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 ++ LITG TG G+Y+T L Y V R + N Sbjct: 5 KRKILITGGTGMLGAYVTSALKDTDYNVIVTERNTLN----------------------- 41 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 L+ ++ +I KPD + + AA++ V + P ++ +A + Sbjct: 42 ----LSVPEAIFSYITAEKPDVILHFAAETDVDLCEREPARAGIYNHLATEQIAQAAKFC 97 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPP-PQSETTPFHPRSPYAASKCAAHWYTVN 198 SS +FG +E P + Y SK N Sbjct: 98 GAW------LLYLSSSNVFGGEGKLSYNELDIPLPMNYYGRSKLIGESSVRN 143 >1KC3-A nrPDB Length = 299 Score = 59.5 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 36/170 (21%), Positives = 60/170 (35%), Gaps = 31/170 (18%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 L+ G TGQ G L L G N I +D H+ Sbjct: 2 NILLFGKTGQVGWELQRSLAPVG------------------NLIALDVHSKEFC------ 37 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 D ++ + + ++PD + N AA + V + P+ + AT +EA+ Sbjct: 38 GDFSNPKGVAETVRKLRPDVIVNAAAHTAVDKAESEPELAQLLNATS----VEAIAKAAN 93 Query: 150 DSGRTVKYYQAGSSEMF-GSTPPPQSETTPFHPRSPYAASKCAAHWYTVN 198 ++G V + +F G+ P ET P + Y +K A + Sbjct: 94 ETGAWV--VHYSTDYVFPGTGDIPWQETDATSPLNVYGKTKLAGEKALQD 141 >1ZZE-A nrPDB Length = 342 Score = 57.5 bits (137), Expect = 9e-09, Method: Composition-based stats. Identities = 35/161 (21%), Positives = 58/161 (36%), Gaps = 22/161 (13%) Query: 19 KADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPH 78 K D+ V+ + L+TG G S++ E LL GY+V G R +S ++ ++ Sbjct: 2 KIDNAVLPEGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSAS-----KLANLQKRWD 56 Query: 79 NVNKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAA-QSHVA--VSFEIPDYTADV-VA 134 + + + + DEV AA +H+A VSF Sbjct: 57 AKYPGRFE--------TAVVEDMLKQGAYDEVIKGAAGVAHIASVVSFSNKYDEVVTPAI 108 Query: 135 TGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSE 175 G L L A + + ++ S + P P E Sbjct: 109 GGTLNALRAAAA----TPSVKRFVLTSS-TVSALIPKPNVE 144 >4QQR-A nrPDB Length = 301 Score = 56.0 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 52/269 (19%), Positives = 86/269 (31%), Gaps = 28/269 (10%) Query: 74 YIDPHNVNKALMKLHYAD--LTDASSLRRWIDVIKPDEVYNLA---AQSHVAVSFEIPDY 128 + + Y L D S+ I+ +KP V+N A + +V Sbjct: 26 GLLGKLCEAQGITYTYGSGRLQDRQSIVADIESVKPSHVFNAAGVTGRPNVDWCESHKVE 85 Query: 129 TADVVATGALRLLEAVRSHTIDSGRTVK--YYQAGSSEMFGSTPPPQSETTPFHPRSPYA 186 T G L L + R + ++ S GS + E TP S Y+ Sbjct: 86 TIRTNVAGTLTLADICREKGLVLINYATGCIFEYDSGHPLGSGIGFKEEDTPNFTGSFYS 145 Query: 187 ASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLF- 245 +K NY L I + +PR NF+T K+ K+ Sbjct: 146 KTKAMVEELLKNYENVCTLRVRMPISSDLTNPR---NFIT----------KIARYEKVVD 192 Query: 246 LGNLQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYL--GLNWK 303 + N D + + M ++ Y + E L++ Y+ WK Sbjct: 193 IPNSMTILD-----ELLPISIEMAKRNLTGIYNFTNPGVVSHNEILEMYRDYIDPSFTWK 247 Query: 304 DYVEIDQRYFRPAEVDNLQGDASKAKEVL 332 ++ +Q A N + DA+K K Sbjct: 248 NFTLEEQAKVIVAPRSNNELDATKLKTEF 276 >4QUK-A nrPDB Length = 319 Score = 55.6 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 55/334 (16%), Positives = 110/334 (32%), Gaps = 34/334 (10%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 + +TG +G S+L LL +GY V +R ++ ++++H+ + K ++L Sbjct: 1 NVVCVTGASGYIASWLVRLLLHRGYTVKATVRDPND--PKKVDHLVKL--DGAKERLQLF 56 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIP-DYTADVVATGALRLLEAVRSH 147 A+L + + + V++ A+ + V + P D G L +L + Sbjct: 57 KANLLEEGAFDSVVQGCH--GVFHTASPFYHDV--KDPQAELIDPALKGTLNVLNSCAK- 111 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPPPQSET---TPFHPRSPYAASKCAAHWYTVNYREAYG 204 S + S P++ +K + WY V+ A Sbjct: 112 ---SPSLKRVVLTSSIAAVAYNGKPRTPDVVVDETWFTDADFCAK-SNLWYVVSATLAEE 167 Query: 205 LFACNGILFNHESPR-RGENFVTRKITRALGRIKVGLQTKLFLGN---LQASRDWGFAGD 260 A + N+ V + + + L G AS W D Sbjct: 168 -AAWKFVKENNIDMVTINPAMVIGPLLQPVLNTSAAAILNLINGAQTFPNASFGWVNVKD 226 Query: 261 YVEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAE--- 317 A L + + H + E + + + + Y + + Sbjct: 227 VANAHILAYE-------NASASGRHCLVERVAHYSEVVRILRELYPSLQLPEKCADDKPY 279 Query: 318 VDNLQGDASKAKEV-LGWKP-QVGFEKLVKMMVD 349 V Q KAK + L + P +V ++ V+ + + Sbjct: 280 VPIYQVSKEKAKSLGLEYTPLEVSIKETVESLKE 313 >6GCS-E nrPDB Length = 375 Score = 54.5 bits (129), Expect = 7e-08, Method: Composition-based stats. Identities = 55/328 (16%), Positives = 102/328 (31%), Gaps = 62/328 (18%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 A + G G GSYLT L G V R H+ + ++ Sbjct: 55 TATVFGANGFLGSYLTAKLAKHGTTVVVPYREEM-----AKRHLKVTGD---LGVVNFLE 106 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 DL + S+ + D V NL + + +F DV GA R+ EAV+ H I Sbjct: 107 MDLRNLESIDEAVR--HSDIVVNLIGREYETKNFN----YYDVHVEGARRIAEAVKKHNI 160 Query: 150 DSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLFACN 209 +Y P S + +K T + + Sbjct: 161 -----ARYIHVS--AFNAEIDSP----------SEFNHTKGLGEQVTKD------IVPWA 197 Query: 210 GILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQA-SRDWGFAGDYVEAMWLM 268 I+ R R+ L R + L N + + D A+ + Sbjct: 198 TIV-------RPAPMFGREDKWFLDR--MARSPCLVSANKFQETSNPVHVIDVAAALERI 248 Query: 269 LQQEK--PDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFRPAEVDNLQGDA- 325 + + + + T ++ +D+ L ++ R E+ A Sbjct: 249 CFDDSTVAQTFELYGPQKFTQKQIIDMVSETL-----------RKEVRHIELPKALYQAY 297 Query: 326 SKAKEVLGWKPQVGFEKLVKMMVDEDLE 353 +KA + + W P +++ + + + ++ Sbjct: 298 TKATQAI-WWPTYSPDQVERQFLSQKID 324 >4NBT-A nrPDB Length = 240 Score = 48.3 bits (113), Expect = 5e-06, Method: Composition-based stats. Identities = 38/211 (18%), Positives = 68/211 (32%), Gaps = 30/211 (14%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+A+ITG G + +G +V ++ + N M L+ Sbjct: 7 KVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYS------------HPNVEGMYLN 54 Query: 89 YADLTDASSL-RRWIDVI-KPDEVYNLAA--QSHVAVSFEIPDYTA--DVVATGALRLLE 142 D+T + ID K D + N A + + + A DV G L Sbjct: 55 VTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLTR 114 Query: 143 AVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREA 202 V +G + +FG+ YAA+K T+ + + Sbjct: 115 LVGPQMQTNGYGSIINISSVVGVFGNIGQAN-----------YAATKAGVIGLTMTWAKE 163 Query: 203 YGLFACNGILFNHESPRRGENFVTRKITRAL 233 + L N + N +P + + + + L Sbjct: 164 FALKGANVRV-NAIAPGYIMTDILKTVPQDL 193 >1K2W-A nrPDB Length = 256 Score = 47.9 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 30/180 (16%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K ALITG G E + +G V N R I P AL Sbjct: 6 KTALITGSARGIGRAFAEAYVREGARVAIADI---NLEAARATAAEIGPAACAIAL---- 58 Query: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAAQ----SHVAVSFEIPDYTADVVATGALR 139 D+TD +S+ R + + D + N AA V ++ E D + +G L Sbjct: 59 --DVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLF 116 Query: 140 LLEAVRSHTIDSGRTVKYYQ-AGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVN 198 +++AV I GR K A + G Y A+K A T + Sbjct: 117 MMQAVARAMIAGGRGGKIINMASQAGRRGEALVGV-----------YCATKAAVISLTQS 165 >4AVY-A nrPDB Length = 242 Score = 47.1 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 35/179 (19%), Positives = 58/179 (32%), Gaps = 33/179 (18%) Query: 31 ALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYA 90 L+TG + G+ + G EV L + H ++ Sbjct: 14 VLVTGGSSGIGAAIAMQFAELGAEVVALGLDADG------------VHAPRHPRIRREEL 61 Query: 91 DLTDASSLRRWIDVI-KPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 D+TD+ L+R + + + D + N A S ++ T + V L L A+ + + Sbjct: 62 DITDSQRLQRLFEALPRLDVLVNNAGISRDREEYD--LATFERVLR--LNLSAAMLASQL 117 Query: 150 DSGRTVK-----YYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAY 203 + A FGS P Y+ASK A T + Y Sbjct: 118 ARPLLAQRGGSILNIASMYSTFGSADRPA-----------YSASKGAIVQLTRSLACEY 165 >3SLK-A nrPDB Length = 795 Score = 47.1 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 44/130 (33%), Gaps = 11/130 (8%) Query: 24 VVEPRKIALITGITGQDGSYLTEFL-LGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNK 82 V + L+TG TG G+ + L + +G L+ R + + Sbjct: 526 VWDAAGTVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELV--AQLTAYG 583 Query: 83 ALMKLHYADLTDASSLRRWI----DVIKPDEVYNLAAQSHVAVS----FEIPDYTADVVA 134 A + L D+ D +L + + D V + A VS E D Sbjct: 584 AEVSLQACDVADRETLAKVLASIPDEHPLTAVVHAAGVLDDGVSESLTVERLDQVLRPKV 643 Query: 135 TGALRLLEAV 144 GA LLE + Sbjct: 644 DGARNLLELI 653 >5YWN-A nrPDB Length = 334 Score = 46.4 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 42/291 (14%), Positives = 89/291 (30%), Gaps = 41/291 (14%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 ++G TG + +L KGY+V G +R S + +Y + + ++K+ Sbjct: 4 SVFVSGATGYLAQQIIALVLSKGYKVVGSVR--SEEKGANLKKLY--GDDFSYEVVKV-- 57 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVAT-GALRLLEAVRSHT 148 L + + P+ L S V E + + A G +L++++ Sbjct: 58 --LEQKGAFDEALKK-HPEVTIFLHTASPVTFEVEDTEKEILIPAINGTKYVLQSIKDVA 114 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPPQS------------ETTPFHPRSPYAASKCAAHWYT 196 R V + + P E + H Y SK A Sbjct: 115 PQITRVVYTSSVVAMSVPEELGSPDVVLSEASWSSLSYEQSKTHGVLAYFGSKQFAERAA 174 Query: 197 VNYREA----YGLFACNGILFNHESPRRGENFVTRKI------TRALGRIKVGLQTKLFL 246 + E + L N + P+ + V + ++ ++ Sbjct: 175 WEFVEQEKPNFALSTVNPVYI--FGPQAKDEEVKGTLNHSAEMVNSVLKLNKDDDVPATT 232 Query: 247 GNLQASRDWGFAGDYVEAMWLMLQQEKP-DDYVVATEEGHTVEEFLDVSFG 296 G + D +A ++++ + ++ + + LDV Sbjct: 233 GT------FIDVRDVAKAHLAAFEKDEAKGERLLLSNTRFNGQTLLDVVRK 277 >5U9P-A nrPDB Length = 265 Score = 44.4 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 41/194 (21%), Positives = 64/194 (32%), Gaps = 33/194 (17%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 + ALITG G L L G + + R+ + + A+ Sbjct: 21 RRALITGSGRGIGLTLARGLAEAGAAIV-INDRNEEKAATLARRFRDEGFAADHAVF--- 76 Query: 89 YADLTDASSLRRWIDVIK-----PDEVYNLAA-QSHVAVSFEIPDYTAD---VVATGALR 139 D+ + + +R ID + D + N A Q + PD V G Sbjct: 77 --DVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFN 134 Query: 140 LLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPR-SPYAASKCAAHWYTV- 197 + +AV H I G K S ++ P +PYAA+K A T Sbjct: 135 VAQAVARHMIARG-HGKIINICS-----------VQSELARPTIAPYAATKGAVRMLTKG 182 Query: 198 ---NYREAYGLFAC 208 ++ YG+ A Sbjct: 183 MCADWAR-YGIQAN 195 >3PVZ-A nrPDB Length = 399 Score = 44.4 bits (103), Expect = 8e-05, Method: Composition-based stats. Identities = 30/188 (15%), Positives = 61/188 (32%), Gaps = 27/188 (14%) Query: 13 ESITAPKADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINH 72 + I A + + V + L+ G G G +T+ + + + ++ S N + + Sbjct: 20 QDINANEKELQSVVSQSRFLVLGGAGSIGQAVTKEIFKRNPQKLHVVDISENNMVELVRD 79 Query: 73 IYIDPHNVNKAL--MKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDY-- 128 I +N L + + ++ + D V NL+A HV S + P Sbjct: 80 IRSSFGYINGDFQTFALDIGSIEYDAFIK---ADGQYDYVLNLSALKHV-RSEKDPFTLM 135 Query: 129 -TADVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAA 187 DV + ++ KY+ + + +P + A Sbjct: 136 RMIDVNVFNTDKTIQ-----QSIDAGAKKYFCVSTDK-------------AANPVNMMGA 177 Query: 188 SKCAAHWY 195 SK + Sbjct: 178 SKRIMEMF 185 >5ILO-A nrPDB Length = 271 Score = 44.4 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 37/208 (17%), Positives = 58/208 (27%), Gaps = 44/208 (21%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K A++TG G G +++ LL G +I N + + + Sbjct: 16 KNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDN-----LEEFVKLRAAHPTQSVMII 70 Query: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAAQSHVAVSFEIPD--YTADVVATGALR-L 140 D+ + + + I D V N+A F D T V G + Sbjct: 71 KMDVANKKGVEATYEEIAKTFGNIDIVVNVAGI------FNDKDVQRTLLVNLGGIINST 124 Query: 141 LEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYR 200 L A+ D+G S + G P Y A+K Sbjct: 125 LSALPYMGKDNGGKGGIV-VNMSSVVGLDPMFIIPV--------YGATKAGI-------- 167 Query: 201 EAYGLFACNGILFNHESPRR--GENFVT 226 +E + G FVT Sbjct: 168 ------INFTRCLANEKYYQRSGIKFVT 189 >2FWM-X nrPDB Length = 250 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 30/179 (16%), Positives = 48/179 (26%), Gaps = 36/179 (20%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K +TG G + G +V G + + + Sbjct: 8 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ----------------EQYPFATE 51 Query: 89 YADLTDASSLRRW-----IDVIKPDEVYNLAAQSHVAV----SFEIPDYTADVVATGALR 139 D+ DA+ + + + + D + N A + S E T V GA Sbjct: 52 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 111 Query: 140 LLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVN 198 L + + R S TP S Y ASK A ++ Sbjct: 112 LFQQT-MNQFRRQRGGAIVTVASDAA----------HTPRIGMSAYGASKAALKSLALS 159 >3WOH-A nrPDB Length = 251 Score = 42.1 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 35/165 (21%), Positives = 57/165 (34%), Gaps = 19/165 (11%) Query: 14 SITAPKADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHI 73 S+T P A S K+AL+TG + G + L G V + + + I Sbjct: 2 SMTGPGALSG-----KVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEI 56 Query: 74 YIDPHNVNKALMKLHYADLTDASSLRRWIDVIK-----PDEVYNLAA--QSHVAVSFEIP 126 D++DA + R + + D + N A + +A S + Sbjct: 57 ERLGGTARSYRC-----DVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDE 111 Query: 127 DYTA--DVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGST 169 DY A + GA ++A I + S +FGS Sbjct: 112 DYDAVMNTNLKGAFLFIKACYFGFIRKRSGSIINISSVSGVFGSA 156 >4B4O-A nrPDB Length = 298 Score = 41.7 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 38/252 (15%), Positives = 66/252 (26%), Gaps = 57/252 (22%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 L+ G TG G+ LT+ L +G+EV + R+ RI + + Sbjct: 2 RVLVGGGTGFIGTALTQLLNARGHEVTLVSRKP---GPGRITWDELAASGLPSC------ 52 Query: 90 ADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDY----TADVVATG----ALRLL 141 D NLA ++ P T G +LL Sbjct: 53 ------------------DAAVNLAGEN-----ILNPLRRWNETFQKEVLGSRLETTQLL 89 Query: 142 EAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYRE 201 + + + S E +P ++ + Sbjct: 90 AKAITKAPQPPKAWVLVTGVAYYQP-SLTAEYDEDSPGGDFDFFSN-------LVTKWEA 141 Query: 202 AYGLFACNGILFNHESPR---RGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFA 258 A L + S RG + + R+ +G +G+ W Sbjct: 142 AARLPGDSTRQVVVRSGVVLGRGGGAMGHMLLPF--RLGLGGP----IGSGHQFFPWIHI 195 Query: 259 GDYVEAMWLMLQ 270 GD + L+ Sbjct: 196 GDLAGILTHALE 207 >3U9L-A nrPDB Length = 324 Score = 41.4 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 48/133 (36%), Gaps = 10/133 (7%) Query: 24 VVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKA 83 +V +KI LITG + G E L G G+ V+ +R N + I + + Sbjct: 1 MVMSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVD 60 Query: 84 LMKLHYADLTDASSLRRWIDVI-----KPDEVYNLAA-QSHVAVSFEIPDYT---ADVVA 134 L L D+ S+ R ID I + D + + A P+ D+ Sbjct: 61 LRTLEL-DVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINV 119 Query: 135 TGALRLLEAVRSH 147 R+ A H Sbjct: 120 LSTQRVNRAALPH 132 >6CGE-A nrPDB Length = 328 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 44/123 (35%), Gaps = 7/123 (5%) Query: 28 RKIALITGITGQDGSYLTEFLLG---KGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKAL 84 R + LITG + G +L L + ++V+ +R + + Sbjct: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 Query: 85 MKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVA---VSFEIPDYT-ADVVATGALRL 140 ++L D ++ R + + D + A + E + DV G +R+ Sbjct: 63 LQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 Query: 141 LEA 143 L+A Sbjct: 123 LQA 125 >1A27-A nrPDB Length = 289 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 44/123 (35%), Gaps = 7/123 (5%) Query: 28 RKIALITGITGQDGSYLTEFLLG---KGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKAL 84 R + LITG + G +L L + ++V+ +R + + Sbjct: 2 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 61 Query: 85 MKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVA---VSFEIPDYT-ADVVATGALRL 140 ++L D ++ R + + D + A + E + DV G +R+ Sbjct: 62 LQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 121 Query: 141 LEA 143 L+A Sbjct: 122 LQA 124 >3A28-C nrPDB Length = 258 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 41/219 (18%), Positives = 69/219 (31%), Gaps = 26/219 (11%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 K+A++TG G ++E L G+++ + Q I + KA+ Sbjct: 2 SKVAMVTGGAQGIGRGISEKLAADGFDI--AVADLPQQEEQAAETIKLIEAADQKAV--F 57 Query: 88 HYADLTDASSLRRWIDVIKP-----DEVYNLAA----QSHVAVSFEIPDYTADVVATGAL 138 D+TD ++ ID D + N A + + V+ E V Sbjct: 58 VGLDVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVF 117 Query: 139 RLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVN 198 ++A + G K A S P S Y+ +K A T Sbjct: 118 FGIQAASRKFDELGVKGKIINAASIAAIQGFPI----------LSAYSTTKFAVRGLTQA 167 Query: 199 YREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIK 237 + A G N +P + +I L +I Sbjct: 168 AAQE---LAPKGHTVNAYAPGIVGTGMWEQIDAELSKIN 203 >1QYD-A nrPDB Length = 313 Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 38/239 (15%), Positives = 67/239 (28%), Gaps = 43/239 (17%) Query: 25 VEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKAL 84 ++ + LI G TG G + + G+ + L R N ++ + Sbjct: 1 MDKKSRVLIVGGTGYIGKRIVNASISLGHPTYVLFRPEVVSNIDKVQMLLYFKQL----G 56 Query: 85 MKLHYADLTDASSLRRWIDVIKPDEVYNLAA---QSHVAVSFEIPDYTADVVATGALRLL 141 KL A L D L + + D V + A SH L+L+ Sbjct: 57 AKLIEASLDDHQRLVDALK--QVDVVISALAGGVLSH--------------HILEQLKLV 100 Query: 142 EAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYRE 201 EA++ ++G ++ + FG P P + E Sbjct: 101 EAIK----EAGNIKRFLPSE----FGM--DPDIMEHALQP----GSITFIDKRKVRRAIE 146 Query: 202 AYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGD 260 A + + N + + G + L G+ W D Sbjct: 147 AASIPYTY-VSSNMFAGYFAGSLAQLD-----GHMMPPRDKVLIYGDGNVKGIWVDEDD 199 >2V6G-A nrPDB Length = 364 Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 54/300 (18%), Positives = 94/300 (31%), Gaps = 41/300 (13%) Query: 28 RKIALITGITGQDGSYLTEFL----LGKG-YEVHGLIRRSSNFNTQRINHIYIDPHNVNK 82 +ALI G+TG G+ L E L G ++V+G+ RR+ P Sbjct: 1 SSVALIVGVTGIIGNSLAEILPLADTPGGPWKVYGVARRT-------------RPAWHED 47 Query: 83 ALMKLHYADLTDASSLRRWIDVIKP-DEVYNLAAQSHVAVSFEIPDYTADVVATGALRLL 141 + D++D + P +V ++ + S E + + +L Sbjct: 48 NPINYVQCDISDP---DDSQAKLSPLTDVTHVFYVTWANRSTEQ--ENCEANSKMFRNVL 102 Query: 142 EAVRSHTID----SGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKC-AAHWYT 196 +AV + + S +T + + G E +G T PR Y Sbjct: 103 DAVIPNCPNLKHISLQTGRKHYMGPFESYGKIESHDPPYTEDLPRLKYMNFYYDLEDIML 162 Query: 197 VNYREAYGLFACNGILFN--HESPRRGENFVTRKITRALGRIKVGLQTKLF----LGNLQ 250 + GL N SP N V A G + + Sbjct: 163 EEVEKKEGLTWSVHRPGNIFGFSPYSMMNLVGTLCVYAAICKHEGKVLRFTGCKAAWDGY 222 Query: 251 ASRDWGFAGDYV--EAMWLMLQ-QEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVE 307 + D A D + +W + K + + V+ + + F V G+ +Y E Sbjct: 223 S--DCSDA-DLIAEHHIWAAVDPYAKNEAFNVSNGDVFKWKHFWKVLAEQFGVECGEYEE 279 >2GDZ-A nrPDB Length = 267 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 36/190 (18%), Positives = 54/190 (28%), Gaps = 23/190 (12%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+AL+TG G E LL KG +V + + Sbjct: 8 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTL----FI 63 Query: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAAQSHVAVSFEIPDYTADVVAT-GALRLLE 142 D+ D LR + + D + N A + ++E V G L+ Sbjct: 64 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAG-VNNEKNWEKTLQINLVSVISGTYLGLD 122 Query: 143 AVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREA 202 + G + S + G P Q Y ASK +T + A Sbjct: 123 YMSKQNGGEGGII----INMSSLAGLMPVAQQPV--------YCASKHGIVGFTRSAALA 170 Query: 203 YGLFACNGIL 212 L L Sbjct: 171 ANLMNSGVRL 180 >1GEG-A nrPDB Length = 256 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 44/201 (21%), Positives = 71/201 (35%), Gaps = 30/201 (14%) Query: 28 RKIALITGITGQ-DGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMK 86 +K+AL+TG GQ G + L+ G+ V N T + I+ + +K Sbjct: 2 KKVALVTG-AGQGIGKAIALRLVKDGFAV---AIADYNDATAKAVASEINQAGGHAVAVK 57 Query: 87 LHYADLTDASSLRRWIDVIKP-----DEVYNLA--AQSHVAVSF--EIPDYTADVVATGA 137 + D++D + ++ + D + N A A S S EI D ++ G Sbjct: 58 V---DVSDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGV 114 Query: 138 LRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTV 197 + ++A G K A S G P+ + Y++SK A T Sbjct: 115 IWGIQAAVEAFKKEGHGGKIINACSQA--GHVGNPE--------LAVYSSSKFAVRGLTQ 164 Query: 198 NYREAYGLFACNGILFNHESP 218 A GI N P Sbjct: 165 TAARD---LAPLGITVNGYCP 182 >4E6P-A nrPDB Length = 259 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 30/140 (21%), Positives = 45/140 (32%), Gaps = 8/140 (5%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K ALITG G E + +G V + Q I + V + + Sbjct: 9 KSALITGSARGIGRAFAEAYVREGATV-AIADIDIERARQAAAEIGPAAYAVQMDVTRQD 67 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQ----SHVAVSFEIPDYTADVVATGALRLLEAV 144 D A+++ D + N AA V ++ E + + G L L+A Sbjct: 68 SIDAAIAATVEHAGG---LDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLFTLQAA 124 Query: 145 RSHTIDSGRTVKYYQAGSSE 164 I GR K S Sbjct: 125 ARQMIAQGRGGKIINMASQA 144 >1YXM-A nrPDB Length = 303 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 17/125 (13%), Positives = 42/125 (33%), Gaps = 10/125 (8%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 ++A++TG G + + LL G V R+ + P ++ + Sbjct: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI- 77 Query: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAAQSHVA----VSFEIPDYTADVVATGALR 139 ++ + + + K + + N ++ +S + + TG Sbjct: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 Query: 140 LLEAV 144 + +AV Sbjct: 138 MCKAV 142 >3U5T-A nrPDB Length = 267 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 35/185 (18%), Positives = 63/185 (34%), Gaps = 31/185 (16%) Query: 23 TVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNK 82 +++E K+A++TG + G+ + L G+ V N+ + + Sbjct: 22 SMMETNKVAIVTGASRGIGAAIAARLASDGFTVVI------NYAGKAAAAEEVAGKIEAA 75 Query: 83 ALMKL-HYADLTDASSLRRWIDVIK-----PDEVYNLAAQSHVAVSFEIPDYTAD----V 132 L AD++D +++RR + D + N A + E D D V Sbjct: 76 GGKALTAQADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAV 135 Query: 133 VATGALRLL-EAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCA 191 G L EA + + + +S++ G P YAA+K Sbjct: 136 NLKGTFNTLREAAQRLRV----GGRIINMSTSQV-GLLHPSYGI---------YAAAKAG 181 Query: 192 AHWYT 196 T Sbjct: 182 VEAMT 186 >3PXX-A nrPDB Length = 287 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 36/132 (27%), Gaps = 13/132 (9%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYE------VHGLIRRSSNFNTQRINHIYIDPHNVNK 82 K+ L+TG G L +G + H + T R Sbjct: 11 KVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEVEKTG 70 Query: 83 ALMKLHYADLTDASSLRRWIDVI-----KPDEVYNLAAQSHVAV--SFEIPDYTADVVAT 135 D+ D +++ R + K D V A + + DV Sbjct: 71 RKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGAHLPVQAFADAFDVDFV 130 Query: 136 GALRLLEAVRSH 147 G + + A + Sbjct: 131 GVINTVHAALPY 142 >4DBZ-A nrPDB Length = 281 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 38/211 (18%), Positives = 70/211 (33%), Gaps = 29/211 (13%) Query: 18 PKADSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIR--RSSNFNTQRINHIYI 75 P+ + ++AL+TG T G + L +G V R + + + Sbjct: 16 PRGSHMATQDSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGV 75 Query: 76 DPHNVNKALMKLHYADLTDASSLRRWIDVIKP-DEVYNLAAQSHVAVSFEIPD----YTA 130 + + + + + + ++ P D + N A + + E+ D Sbjct: 76 EADGRTCDVRSVPEIE----ALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVV 131 Query: 131 DVVATGALRLLEAVRSHT--IDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAAS 188 + TG R+ + V ++ G A + G +PY+AS Sbjct: 132 ETNLTGVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGLVHA-----------APYSAS 180 Query: 189 KCAAHWYTVNYREAYGL-FACNGILFNHESP 218 K V + +A GL A GI N P Sbjct: 181 K----HGVVGFTKALGLELARTGITVNAVCP 207 >3OSU-A nrPDB Length = 246 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 40/217 (18%), Positives = 68/217 (31%), Gaps = 34/217 (15%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL- 87 K AL+TG + G + L +GY V + N+ + + K + Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNV------AVNYAGSKEKAEAVVEEIKAKGVDSFA 58 Query: 88 HYADLTDASSLRRWIDVI-----KPDEVYNLAAQS----HVAVSFEIPDYTADVVATGAL 138 A++ DA ++ I + D + N A + + + + D D G Sbjct: 59 IQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVF 118 Query: 139 RLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVN 198 ++ T R S + G+ P Y A+K T + Sbjct: 119 N---CIQKATPQMLRQRSGAIINLSSVVGAVGNPGQAN--------YVATKAGVIGLTKS 167 Query: 199 YREAYGLFACNGILFNHESPRRGENFVTRKITRALGR 235 A GI N +P F+ +T AL Sbjct: 168 AARE---LASRGITVNAVAP----GFIVSDMTDALSD 197 >1UZM-A nrPDB Length = 247 Score = 38.3 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 32/227 (14%), Positives = 67/227 (29%), Gaps = 44/227 (19%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 + L+TG G + + L G++V R S + Sbjct: 15 SRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSG-----------------APKGLFG 57 Query: 88 HYADLTDASSLRRWIDVIK-----PDEVYNLAAQSH----VAVSFEIPDYTADVVATGAL 138 D+TD+ ++ R ++ + + + A S + ++ E + + TGA Sbjct: 58 VEVDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAF 117 Query: 139 RLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVN 198 R+ + + + S ++G ++ YAASK + Sbjct: 118 RVAQRASRSMQRNKFGRMIFIGSVSGLWG-----------IGNQANYAASKAGVIGMARS 166 Query: 199 YREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLF 245 N + ++ +TRAL + Sbjct: 167 IARE-------LSKANVTANVVAPGYIDTDMTRALDERIQQGALQFI 206 >2NM0-A nrPDB Length = 253 Score = 38.3 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 36/227 (15%), Positives = 66/227 (29%), Gaps = 45/227 (19%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 + L+TG G + G +V R Sbjct: 21 SRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGE-----------------PPEGFLA 63 Query: 88 HYADLTDASSLRRWIDVIK----PDEVYNLAA-----QSHVAVSFEIPDYTADVVATGAL 138 D+TD + + I+ P EV A Q + +S E + TG Sbjct: 64 VKCDITDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTF 123 Query: 139 RLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVN 198 R+++ + + + + + GS YAASK + + Sbjct: 124 RVVKRANRAMLRAKKGRVVLISSVVGLLGSAGQAN-----------YAASKAGLVGFARS 172 Query: 199 YREAYGLFACNGILFNHESPRRGENFVTRKIT-----RALGRIKVGL 240 G I FN +P + +T+ +T + ++ +G Sbjct: 173 LARELG---SRNITFNVVAPGFVDTDMTKVLTDEQRANIVSQVPLGR 216 >3RWB-A nrPDB Length = 247 Score = 38.3 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 49/154 (31%), Gaps = 22/154 (14%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K AL+TG G + L G V + + Sbjct: 7 KTALVTGAAQGIGKAIAARLAADGATVIVSDINAEG---------AKAAAASIGKKARAI 57 Query: 89 YADLTDASSLRRWIDVIK-----PDEVYNLAAQSHVA-VSFEIPDYT-----ADVVATGA 137 AD++D S++ I+ D + N A S V V+++ D DV TG Sbjct: 58 AADISDPGSVKALFAEIQALTGGIDILVNNA--SIVPFVAWDDVDLDHWRKIIDVNLTGT 115 Query: 138 LRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPP 171 + A +G+ + S+ F TP Sbjct: 116 FIVTRAGTDQMRAAGKAGRVISIASNTFFAGTPN 149 >5D01-A nrPDB Length = 379 Score = 38.3 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 28/163 (17%), Positives = 52/163 (31%), Gaps = 18/163 (11%) Query: 35 GITGQDGSYLTEFLLGKGYEVHGLIRRS-SNFNTQRINHIYIDPHNVNKALMKLHYADLT 93 G +G + L + L KG+E+H + NT N + + A+ K DLT Sbjct: 17 GGSGIIATELGKQLAEKGHEIHFITSSIPFRLNTYHPNIHFHEVEVNQYAVFKYPPYDLT 76 Query: 94 DASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLE----AVRSHTI 149 AS + + D ++ A H ++ G + L V + Sbjct: 77 LASKIAEVAERENLDIIHAHYALPHAVCAYLAKQMLKRN--IGIVTTLHGTDITVLGYDP 134 Query: 150 DSGRTVKYYQAGSS-----------EMFGSTPPPQSETTPFHP 181 +++ S E + P + T ++ Sbjct: 135 SLKDLIRFAIESSDRVTAVSSALAAETYDLIKPEKKIETIYNF 177 >4BO1-A nrPDB Length = 269 Score = 37.9 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 43/217 (19%), Positives = 74/217 (34%), Gaps = 21/217 (9%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+AL+TG + G + L G V G +S ++I L+ Sbjct: 28 KVALVTGASRGIGQAIALELGRLGAVVIGTA--TSASGAEKIAETLKANGVEGAGLVLDV 85 Query: 89 YADLTDASSLRRWIDVI-KPDEVYNLAAQS----HVAVSFEIPDYTADVVATGALRLLEA 143 +D + A++L + +P V N A + V + + + RL +A Sbjct: 86 SSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRLSKA 145 Query: 144 VRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAY 203 V + R + GS + G+ YAA+K +T Sbjct: 146 VLR-GMTKARWGRIINIGS--VVGAMGNAGQTN--------YAAAKAGLEGFTRALAREV 194 Query: 204 GLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL 240 G A I N +P + +TR++ A +G Sbjct: 195 GSRA---ITVNAVAPGFIDTDMTRELPEAQREALLGQ 228 >1CYD-A nrPDB Length = 244 Score = 37.5 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 43/252 (17%), Positives = 76/252 (30%), Gaps = 35/252 (13%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 AL+TG G + L G +V + R N+ ++ P ++ Sbjct: 9 RALVTGAGKGIGRDTVKALHASGAKVVAVTR----TNSDLVSLAKECP------GIEPVC 58 Query: 90 ADLTDASSLRRWIDVIKP-DEVYNLAA----QSHVAVSFEIPDYTADVVATGALRLLEAV 144 DL D + + + I P D + N AA Q + V+ E D + V ++ + V Sbjct: 59 VDLGDWDATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMV 118 Query: 145 RSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYG 204 I+ G S + P + Y+++K A T G Sbjct: 119 ARDMINRGVPGSIVNVSSMVAHVTFPNLIT----------YSSTKGAMTMLTKAMAMELG 168 Query: 205 LFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAGDYVEA 264 N T +T ++ + L R + D V + Sbjct: 169 PHKIRVNSVN----------PTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNS 218 Query: 265 MWLMLQQEKPDD 276 + +L Sbjct: 219 ILFLLSDRSAST 230 >4IS3-A nrPDB Length = 268 Score = 37.5 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 47/150 (31%), Gaps = 13/150 (8%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+ +ITG T G + + G +V +T + P Sbjct: 26 KVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFAP-- 83 Query: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAA----QSHVAVSFEIPDYTADVVATGALR 139 DLT ++ + + + D + N A VS E + D+ TG Sbjct: 84 --DLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGVFN 141 Query: 140 LLEAVRSHTIDSGRTVKYYQAGSSEMFGST 169 D+ + V A + +FGS Sbjct: 142 GAWCAYQCMKDAKKGVIINTASVTGIFGSL 171 >5OVL-A nrPDB Length = 300 Score = 37.5 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 45/243 (18%), Positives = 84/243 (34%), Gaps = 50/243 (20%) Query: 10 SDSESITAPKADSTVVEP---RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFN 66 +D+ + TA ++T P + L+TG G + L G++V R S Sbjct: 49 TDNPADTA--GEATAGRPAFVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSG--- 103 Query: 67 TQRINHIYIDPHNVNKALMKLHYADLTDASSLRRWIDVIK-----PDEVYNLAAQS---- 117 + D+TD++++ R ++ + + A S Sbjct: 104 --------------APDDLFGVQCDVTDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAF 149 Query: 118 HVAVSFEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGS-SEMFGSTPPPQSET 176 + ++ E + + TGA R + T+ R + GS S M+G Sbjct: 150 LMRMTEERFEEVINTNLTGAFRCAQRASR-TMQRKRFGRIIFIGSVSGMWG--------- 199 Query: 177 TPFHPRSPYAASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRI 236 ++ YAA+K + A G+ N +P + +TR + RI Sbjct: 200 --IGNQANYAAAKAGLIGMARSISRE---LAKAGVTANVVAPGYIDTEMTRALD---ERI 251 Query: 237 KVG 239 + G Sbjct: 252 QAG 254 >5OVJ-A nrPDB Length = 256 Score = 37.5 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 45/243 (18%), Positives = 84/243 (34%), Gaps = 50/243 (20%) Query: 10 SDSESITAPKADSTVVEP---RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFN 66 +D+ + TA ++T P + L+TG G + L G++V R S Sbjct: 5 TDNPADTA--GEATAGRPAFVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSG--- 59 Query: 67 TQRINHIYIDPHNVNKALMKLHYADLTDASSLRRWIDVIK-----PDEVYNLAAQS---- 117 + D+TD++++ R ++ + + A S Sbjct: 60 --------------APDDLFGVQCDVTDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAF 105 Query: 118 HVAVSFEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGS-SEMFGSTPPPQSET 176 + ++ E + + TGA R + T+ R + GS S M+G Sbjct: 106 LMRMTEERFEEVINTNLTGAFRCAQRASR-TMQRKRFGRIIFIGSVSGMWG--------- 155 Query: 177 TPFHPRSPYAASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRI 236 ++ YAA+K + A G+ N +P + +TR + RI Sbjct: 156 --IGNQANYAAAKAGLIGMARSISRE---LAKAGVTANVVAPGYIDTEMTRALD---ERI 207 Query: 237 KVG 239 + G Sbjct: 208 QAG 210 >3RKU-A nrPDB Length = 287 Score = 37.1 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 46/130 (35%), Gaps = 17/130 (13%) Query: 28 RKIALITGITGQDGSYLTEFLLG--KGYEVHGLIRRSSNFNTQRINHIYIDPHNVNK-AL 84 +K LITG + G L G L R +++ + A Sbjct: 33 KKTVLITGASAGIGKATALEYLEASNGDMKLILAARR----LEKLEELKKTIDQEFPNAK 88 Query: 85 MKLHYADLTDASSLRRWIDVI-----KPDEVYNLAAQSH----VA-VSFEIPDYTADVVA 134 + + D+T A ++ +I+ + D + N A ++ V ++ E D Sbjct: 89 VHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNV 148 Query: 135 TGALRLLEAV 144 T + + +AV Sbjct: 149 TALINITQAV 158 >3V2G-A nrPDB Length = 271 Score = 37.1 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 39/195 (20%), Positives = 63/195 (32%), Gaps = 21/195 (10%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K A +TG + G+ + + L +G V ++ ++ I Sbjct: 32 KTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVA-----I 86 Query: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAAQSHVAVSFEIPDYTA-DVVATGALRLLE 142 AD DA ++ + I D + N A H A E +V+A Sbjct: 87 RADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPFV 146 Query: 143 AVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREA 202 A+RS + G + GS+ +E P+ S Y+ASK A T Sbjct: 147 AIRSASRHLGDGGRIITIGSN---------LAELVPWPGISLYSASKAALAGLTKGLARD 197 Query: 203 YGLFACNGILFNHES 217 G + H Sbjct: 198 LG-PRGITVNIVHPG 211 >3KZV-A nrPDB Length = 254 Score = 37.1 bits (84), Expect = 0.013, Method: Composition-based stats. Identities = 24/180 (13%), Positives = 50/180 (27%), Gaps = 33/180 (18%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+ L+TG++ G + + L + S +++ Y Sbjct: 3 KVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKY-------GDRFFYV 55 Query: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAA-----QSHVAVSFEIPDYTADVVATGAL 138 D+T+ S L++ ++ K D + A Q+ + D+ + Sbjct: 56 VGDITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIV 115 Query: 139 RLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRS--PYAASKCAAHWYT 196 L+ S + S Y +SK A + + Sbjct: 116 SLVGIA--LPELKKTNGNVVFVSSDA------------CNMYFSSWGAYGSSKAALNHFA 161 >4MOW-A nrPDB Length = 256 Score = 36.7 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 30/180 (16%), Positives = 55/180 (30%), Gaps = 33/180 (18%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRI-NHIYIDPHNVNKALMKL 87 K+A++TG + G+ + + L +G V N+ + + + Sbjct: 15 KVAIVTGASKGIGAAIAKALADEGAAVVV------NYASSKAGADAVVSAITEAGGRAVA 68 Query: 88 HYADLTDASSLRRWIDV-----------IKPDEVYNLAAQSHVAVSFEIPDYTADVVATG 136 D++ A+ +R +D + VY A + E D G Sbjct: 69 VGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITE--EHYRRQFDTNVFG 126 Query: 137 ALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYT 196 L +A H + + +S PP S Y+ +K A T Sbjct: 127 VLLTTQAAVKHLGEGASIINISSVVTS-----ITPPASAV--------YSGTKGAVDAIT 173 >6CI9-A nrPDB Length = 259 Score = 36.7 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 32/175 (18%), Positives = 54/175 (30%), Gaps = 31/175 (17%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 + A++TG + G + E G +V R + + + + + Sbjct: 10 RSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDL------DRTVADLSGTRGKVTAV 63 Query: 89 YADLTDASSLRRWIDVIKP-----DEVYNLAAQSHVAVSFEIPDYTAD----VVATGALR 139 AD+TD RR + D V A ++ + V G + Sbjct: 64 RADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVY 123 Query: 140 LLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPR---SPYAASKCA 191 +++A QA ++ G S T P S Y ASK A Sbjct: 124 IVQAA-------------LQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAA 165 >3UN1-A nrPDB Length = 260 Score = 36.7 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 40/245 (16%), Positives = 78/245 (31%), Gaps = 42/245 (17%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 +K+ +ITG + G+ L + Y V T R DP + Sbjct: 28 QKVVVITGASQGIGAGLVRAYRDRNYRVV---------ATSRSIKPSADPD------IHT 72 Query: 88 HYADLTDASSLRRWIDV-----IKPDEVYNLA----AQSHVAVSFEIPDYTADVVATGAL 138 D++ + R + + D + N A A+ V ++ E D+ V G Sbjct: 73 VAGDISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFF 132 Query: 139 RLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVN 198 + + + + G + +S P P + + +K + T + Sbjct: 133 HITQRAAAEMLKQG-SGHIVSITTS----LVDQPMV----GMPSALASLTKGGLNAVTRS 183 Query: 199 YREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFA 258 + + +G+ N SP + + A + + G + RD A Sbjct: 184 LAMEF---SRSGVRVNAVSP----GVIKTPMHPAETHSTLAGLHPV--GRMGEIRDVVDA 234 Query: 259 GDYVE 263 Y+E Sbjct: 235 VLYLE 239 >3OEC-A nrPDB Length = 317 Score = 36.3 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 34/191 (17%), Positives = 56/191 (29%), Gaps = 25/191 (13%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSN----FNTQRINHIYIDPHNVNKAL 84 K+A ITG G L G ++ + + + V + Sbjct: 47 KVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLVEEQG 106 Query: 85 MKLH--YADLTDASSLRRWIDVI-----KPDEVYNLAAQSHVAV--SFEIPDYT--ADVV 133 ++ AD+ D +SL+ +D D + + S+ S ++ Sbjct: 107 RRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDILQTN 166 Query: 134 ATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAH 193 GA AV I+ G+ S G P S YAASK Sbjct: 167 LIGAWHACRAVLPSMIERGQGGSVIFVSS--TVGLRGAPGQ--------SHYAASKHGVQ 216 Query: 194 WYTVNYREAYG 204 ++ G Sbjct: 217 GLMLSLANEVG 227 >3D3W-A nrPDB Length = 244 Score = 36.3 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 33/174 (18%), Positives = 56/174 (32%), Gaps = 25/174 (14%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 + L+TG G + L G V + R ++ +D ++ Sbjct: 8 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD----------LDSLVRECPGIEPV 57 Query: 89 YADLTDASSLRRWIDVIKP-DEVYNLAA----QSHVAVSFEIPDYTADVVATGALRLLEA 143 DL D + R + + P D + N AA Q + V+ E D + +V +++ + Sbjct: 58 CVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQI 117 Query: 144 VRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTV 197 V I G S Q S Y ++K A T Sbjct: 118 VARGLIARGVPGAIVNVSS----------QCSQRAVTNHSVYCSTKGALDMLTK 161 >5ITV-A nrPDB Length = 255 Score = 36.3 bits (82), Expect = 0.020, Method: Composition-based stats. Identities = 32/193 (16%), Positives = 53/193 (27%), Gaps = 28/193 (14%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K LITG G + LG+ V + N + Sbjct: 8 KTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKE--------NNDRLHFV 59 Query: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAAQSHVAVSFEIPDYTAD----VVATGALR 139 D+TD ++ + ++ D + N A VA E+ + V TG Sbjct: 60 QTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFL 119 Query: 140 LLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNY 199 + + H + +G+ + + G P Y ASK T + Sbjct: 120 MSKHALKHMLAAGKG---NIINTCSVGGLVAWPDIPA--------YNASKGGVLQLTKSM 168 Query: 200 REAYGLFACNGIL 212 Y Sbjct: 169 AVDYAKHQIRVNC 181 >5CDY-A nrPDB Length = 244 Score = 36.0 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 44/208 (21%), Positives = 73/208 (35%), Gaps = 26/208 (12%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 KIAL+TG + G + E L+ +G V G +++ N + L+ Sbjct: 6 KIALVTGASRGIGRAIAELLVERGACVIGTA------TSEKGAEAISAYLGENGKGLMLN 59 Query: 89 YADLTDASSLRRWIDVI--KPDEVYNLAAQSHVAVSFEIPD----YTADVVATGALRLLE 142 D T ++ I + D + N A + + + D D T RL + Sbjct: 60 VVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRLSK 119 Query: 143 AVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREA 202 AV + R + GS + G+ YAA+K ++ + Sbjct: 120 AVMRA-MMKKRFGRIITIGS--VVGTMGNAGQVN--------YAAAKAGVIGFSKSLARE 168 Query: 203 YGLFACNGILFNHESPRRGENFVTRKIT 230 A GI N +P E +TR +T Sbjct: 169 ---VASRGITVNVVAPGFIETDMTRTLT 193 >3V8B-A nrPDB Length = 283 Score = 36.0 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 42/136 (30%), Gaps = 16/136 (11%) Query: 22 STVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVN 81 S + +P +ALITG G L G V L R + + + + Sbjct: 22 SMMNQPSPVALITGAGSGIGRATALALAADGVTVGALGRTRT-----EVEEVADEIVGAG 76 Query: 82 KALMKLHYADLTDASSLRRWIDVI-----KPDEVYNLAAQSHVAVSFEI--PDYTADV-- 132 + L AD++D +R + + D V A + V + P + Sbjct: 77 GQAIALE-ADVSDELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIA 135 Query: 133 -VATGALRLLEAVRSH 147 G L + Sbjct: 136 VNLRGTFLTLHLTVPY 151 >5VT6-A nrPDB Length = 269 Score = 36.0 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 37/96 (38%), Gaps = 10/96 (10%) Query: 25 VEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKAL 84 ++ +++A +TG G G+ ++ L G V ++ + + H + Sbjct: 22 MQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRD----- 76 Query: 85 MKLHYADLTDASSLRRWIDVI-----KPDEVYNLAA 115 K + D+ D S R + + K D + N A Sbjct: 77 FKAYAVDVADFESCERCAEKVLADFGKVDVLINNAG 112 >3RSH-A nrPDB Length = 251 Score = 36.0 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 43/223 (19%), Positives = 76/223 (34%), Gaps = 31/223 (13%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+AL+TG + G + E L +G +V G ++ D N M L+ Sbjct: 13 KVALVTGASRGIGKAIAELLAERGAKVIGTA------TSESGAQAISDYLGDNGKGMALN 66 Query: 89 YADLTDASSLRRWIDVI--KPDEVYNLAAQS----HVAVSFEIPDYTADVVATGALRLLE 142 + ++ + I D + N A + + + E + T RL + Sbjct: 67 VTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSK 126 Query: 143 AVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREA 202 AV + R + GS + G+ YAA+K +T + Sbjct: 127 AVLR-GMMKKRQGRIINVGS--VVGTMGNAGQAN--------YAAAKAGVIGFTKSMARE 175 Query: 203 YGLFACNGILFNHESPRRGENFVTRKI-----TRALGRIKVGL 240 A G+ N +P E +T+ + T L ++ G Sbjct: 176 ---VASRGVTVNTVAPGFIETDMTKALNDEQRTATLAQVPAGR 215 >6NRP-A nrPDB Length = 263 Score = 35.6 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 20/143 (13%), Positives = 45/143 (31%), Gaps = 14/143 (9%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 + L+TG + G + L G++V R Q + I N + + Sbjct: 25 RRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMF--- 81 Query: 89 YADLTDASSLRRWIDVIKPDE-----VYNLAAQSHVAV--SFEIPDYT--ADVVATGALR 139 D+ + ++++ ++ V A +H + D+ G Sbjct: 82 --DVNERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYN 139 Query: 140 LLEAVRSHTIDSGRTVKYYQAGS 162 +L+ + I + + S Sbjct: 140 VLKPLIMPMIHLRKGGRIVTLSS 162 >3WTC-A nrPDB Length = 262 Score = 35.6 bits (80), Expect = 0.034, Method: Composition-based stats. Identities = 40/217 (18%), Positives = 65/217 (29%), Gaps = 28/217 (12%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 KIA +TG G + L G +V L + + V Sbjct: 9 KIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALT----- 63 Query: 89 YADLTDASSLRRWIDVIKP-----DEVYNLAAQSHVAVSFE-IP---DYTADVVATGALR 139 AD+++ R + D + N A V + P + + G L Sbjct: 64 -ADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVLW 122 Query: 140 LLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNY 199 ++A + + G K A S E P Y+A+K A T + Sbjct: 123 GMQAAATLFKEKGTKGKIINACSIA--------GHEGYPLLGA--YSATKFAVRALTQSA 172 Query: 200 REAYGLFACNGILFNHESPRRGENFVTRKITRALGRI 236 + A +GI N P + I + + I Sbjct: 173 AKE---LASSGITVNSYCPGIVGTDMWVTIDKRMAEI 206 >2HRB-A nrPDB Length = 274 Score = 35.2 bits (79), Expect = 0.044, Method: Composition-based stats. Identities = 30/212 (14%), Positives = 58/212 (27%), Gaps = 44/212 (20%) Query: 28 RKIALITGITGQDGSYLTEFLLGK-GYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMK 86 ++AL+TG G + L + +V R + + ++ + Sbjct: 2 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDV---ARGQAAVQQLQAEGLSPRFHQ 58 Query: 87 LHYADLTDASSLRRWIDVIK--PDEVYNLAAQSHVAVSFEIP-------DYTADVVATGA 137 L DL +LR ++ + + N AA VA + P + T Sbjct: 59 LDIDDLQSIRALRDFLRKEYGGLNVLVNNAA---VAFKSDDPMPFDIKAEMTLKTNFFAT 115 Query: 138 LRL-------------------LEAVRSH-TIDSGRTVKYY-QAGSSEMFGSTPPPQSET 176 + L+ +R+ +++ + + E Sbjct: 116 RNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVED 175 Query: 177 TP-------FHPRSPYAASKCAAHWYTVNYRE 201 T P SPY SK + Sbjct: 176 TKNEVHEREGWPNSPYGVSKLGVTVLSRILAR 207 >2UVD-A nrPDB Length = 246 Score = 35.2 bits (79), Expect = 0.051, Method: Composition-based stats. Identities = 41/226 (18%), Positives = 71/226 (31%), Gaps = 32/226 (14%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+AL+TG + G + L +G V + N Q+ N + + + + Sbjct: 5 KVALVTGASRGIGRAIAIDLAKQGANVVV----NYAGNEQKANEVVDEIKKLGSDAIA-V 59 Query: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAAQS----HVAVSFEIPDYTADVVATGALR 139 AD+ +A + + + D + N A + + + E D + G Sbjct: 60 RADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFL 119 Query: 140 LLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNY 199 +AV + R + S + G T P Y A+K T Sbjct: 120 CTKAVSRF-MMRQRHGRIVNIAS--VVGVTGNPGQAN--------YVAAKAGVIGLTKTS 168 Query: 200 REAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLF 245 + A I N +P F+ +T L KL Sbjct: 169 AKE---LASRNITVNAIAP----GFIATDMTDVLDENIKAEMLKLI 207 >4RZI-B nrPDB Length = 240 Score = 35.2 bits (79), Expect = 0.053, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 27/67 (40%), Gaps = 3/67 (4%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+ ++TG G+ + + L G +V + NT + + + + M Sbjct: 9 KVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNT---EALGVVANVTDLESMTAA 65 Query: 89 YADLTDA 95 A++TD Sbjct: 66 AAEITDK 72 >1HE4-A nrPDB Length = 206 Score = 35.2 bits (79), Expect = 0.053, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 44/123 (35%), Gaps = 21/123 (17%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K I G TGQ G + GYEV L+R SS + + Sbjct: 4 KKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRL------------PSEGPRPAHVV 51 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 D+ A+ + + + D V V + V++ GA ++ A+++H Sbjct: 52 VGDVLQAADVDKTVAGQ--DAVI-------VLLGTRNDLSPTTVMSEGARNIVAAMKAHG 102 Query: 149 IDS 151 +D Sbjct: 103 VDK 105 >4K6F-A nrPDB Length = 255 Score = 34.8 bits (78), Expect = 0.058, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 35/89 (39%), Gaps = 2/89 (2%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 ++IA++TG G G ++ L G+ V ++ + + ++ + + + Sbjct: 11 KRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPVDV 70 Query: 88 HYADLTDASSLRRWIDVIKP-DEVYNLAA 115 D + + + + P D + N A Sbjct: 71 ADHDSC-QQCIEKIVRDVGPVDILVNNAG 98 >3ZV3-A nrPDB Length = 281 Score = 34.8 bits (78), Expect = 0.064, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 51/151 (33%), Gaps = 24/151 (15%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 +ALITG G L + + +G V L + + +R+ + + H N + Sbjct: 7 VALITGGASGLGRALVDRFVAEGARVAVLDK-----SAERLRELEVA-HGGNAVGVVGDV 60 Query: 90 ADLTDASS-LRRWIDVI-KPDEVYNLAA------------QSHVAVSFEIPDYTADVVAT 135 L D R + K D + A + + +F+ V Sbjct: 61 RSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDD---IFHVNVK 117 Query: 136 GALRLLEAVRSHTIDSGRTVKYYQAGSSEMF 166 G + ++A + S +V + ++ + Sbjct: 118 GYIHAVKACLPALVSSRGSVVF-TISNAGFY 147 >4KMS-A nrPDB Length = 249 Score = 34.8 bits (78), Expect = 0.065, Method: Composition-based stats. Identities = 37/235 (15%), Positives = 74/235 (31%), Gaps = 42/235 (17%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 +IA++TG T G L KG V + SN++ + K +K Sbjct: 10 SEIAIVTGGTRGIGKATALELKNKGLTV--VANFFSNYDAAK--------EMEEKYGIKT 59 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGAL-RLLEAVRS 146 ++ D R+ + I+ + F+ P A ++L + Sbjct: 60 KCWNVADFEECRQAVKEIEEE--------------FKKPVSILVNNAGITKDKMLHRMSH 105 Query: 147 ---HTIDSGRTVKYYQAGSSEM-------FGSTPPPQSETTPFH--PRSPYAASKCAAHW 194 + + + + SS M +G S ++ Y+A+K Sbjct: 106 QDWNDVINVNLNSCFNMSSSVMEQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIG 165 Query: 195 YTVNYRE--AYGLFACNGILFNHESPRR---GENFVTRKITRALGRIKVGLQTKL 244 +T A N I + + V KI ++ + ++G ++ Sbjct: 166 FTKALARETASKNITVNCIAPGYIATEMVGAVPEDVLAKIINSIPKKRLGQPEEI 220 >2BC1-A nrPDB Length = 490 Score = 34.4 bits (77), Expect = 0.070, Method: Composition-based stats. Identities = 34/273 (12%), Positives = 73/273 (26%), Gaps = 39/273 (14%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHI-YIDPHNVNKALMKL 87 K + G G G L E KG EV + + + + N+ + ++L Sbjct: 195 KRVAVVG-AGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQL 253 Query: 88 HYA----DLTDASSLRRWID---VIKPDEVYNLAAQSHVAVSFEIPDYTA---------- 130 + ++ + + I D V Sbjct: 254 AFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLVNKR 313 Query: 131 -DVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEM----------FGSTPPPQSETTPF 179 + G + + + ++ R Y S+ + G+ Sbjct: 314 QETSIPGVYAIGDCATIYD-NATRDTNYIALASNAVRTGIVAAHNACGTDLEGIG-VQGS 371 Query: 180 HPRSPYAASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVG 239 + S Y + T+ + G A +++ P F+ +I Sbjct: 372 NGISIYGL-HMVSTGLTLEKAKRLGFDAAVTEYTDNQKP----EFIEHGNFPVTIKIVYD 426 Query: 240 LQTKLFLGNLQASRDWGFAGDYVEAMWLMLQQE 272 ++ LG A+R+ + L +Q+ Sbjct: 427 KDSRRILGAQMAARE--DVSMGIHMFSLAIQEG 457 >6D9T-A nrPDB Length = 400 Score = 34.4 bits (77), Expect = 0.087, Method: Composition-based stats. Identities = 23/159 (14%), Positives = 49/159 (30%), Gaps = 13/159 (8%) Query: 35 GITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVN-KALMKLHYADLT 93 G +G + L L +G+EVH + + + ++ VN A+ + D+T Sbjct: 32 GGSGIIATELGIKLAERGHEVHFITSNIPFRIRKPLPNMIFHQVEVNQYAVFQYPPYDIT 91 Query: 94 DASSLRRWIDVIKPDEV-YNLAAQSHV-----------AVSFEIPDYTADVVATGALRLL 141 ++ + I D + + A + + + D+ G L Sbjct: 92 LSTKIAEVIKEYDLDLLHMHYAVPHAICGILAREMSGKDIKIMTTLHGTDITVLGYDHSL 151 Query: 142 EAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFH 180 + I+ V ++ E P + Sbjct: 152 QGAIKFGIEKSDIVTSVSKSLAQETHEIIETNKEIIPIY 190 >2QYS-A nrPDB Length = 318 Score = 34.4 bits (77), Expect = 0.090, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 41/98 (41%), Gaps = 10/98 (10%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 + LI G TG G+++ + L G+ + R +S+ T + + ++ ++K Sbjct: 11 KSKILIFGGTGYIGNHMVKGSLKLGHPTYVFTRPNSSKTT-----LLDEFQSLGAIIVK- 64 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEI 125 +L + L + K D V + A + F+I Sbjct: 65 --GELDEHEKLVELMK--KVDVVISALAFPQILDQFKI 98 >1H5Q-A nrPDB Length = 265 Score = 34.0 bits (76), Expect = 0.097, Method: Composition-based stats. Identities = 22/143 (15%), Positives = 37/143 (25%), Gaps = 14/143 (9%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K ++TG G T + G V + R + K + Sbjct: 15 KTIIVTGGNRGIGLAFTRAVAAAGANVAVIYR----SAADAVEVTEKVGKEFGVKT-KAY 69 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDY---------TADVVATGALR 139 D+++ + + I I D ++ VS P DV G Sbjct: 70 QCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFN 129 Query: 140 LLEAVRSHTIDSGRTVKYYQAGS 162 AV + + S Sbjct: 130 TCRAVAKLWLQKQQKGSIVVTSS 152 >3WYE-A nrPDB Length = 256 Score = 34.0 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 42/220 (19%), Positives = 70/220 (31%), Gaps = 30/220 (13%) Query: 28 RKIALITGITGQ-DGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMK 86 +K+AL+TG GQ G + L+ G+ V N T + I+ + +K Sbjct: 2 KKVALVTG-AGQGIGKAIALRLVKDGFAV---AIADYNDATAKAVASEINQAGGHAVAVK 57 Query: 87 LHYADLTDASSLRRWIDVIKP-----DEVYNLAA----QSHVAVSFEIPDYTADVVATGA 137 + D++D + ++ + D + N A + + V+ E V Sbjct: 58 V---DVSDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSV 114 Query: 138 LRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTV 197 ++A G K A S P S Y+ +K A T Sbjct: 115 FFGIQAAVEAFKKEGHGGKIINAASIAAIQGFPI----------LSAYSTTKFAVRGLTQ 164 Query: 198 NYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIK 237 A GI N P + +I L +I Sbjct: 165 TAARD---LAPLGITVNGYCPGIVGTGMWEQIDAELSKIN 201 >3KYB-A nrPDB Length = 390 Score = 33.3 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 24/65 (36%), Gaps = 4/65 (6%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRR---SSNFNTQRINHIYIDPHNVNKAL 84 K LI G G G+ + L KG++VH + +R N R + + H + Sbjct: 3 SKKILIVG-AGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDARDSETNVMVHVYGPHI 61 Query: 85 MKLHY 89 Sbjct: 62 FHTDN 66 >5LCX-A nrPDB Length = 316 Score = 32.9 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 26/101 (25%), Positives = 39/101 (38%), Gaps = 7/101 (6%) Query: 24 VVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKA 83 + E ++ AL+TG G + L KG V R R + NV++ Sbjct: 3 MAEVQRYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLK--ELNVSEN 60 Query: 84 LMKLHYADLTDASSLRRWIDVIKP-----DEVYNLAAQSHV 119 + H D+TD +S+ IK D + N A S V Sbjct: 61 RLVFHQLDVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGV 101 >1Q7C-A nrPDB Length = 244 Score = 32.9 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 30/143 (20%), Positives = 53/143 (37%), Gaps = 19/143 (13%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 KIAL+TG + G + E L +G +V G T + + A K Sbjct: 6 KIALVTGASRGIGRAIAETLAARGAKVIG---------TATSENGAQAISDYLGANGKGL 56 Query: 89 YADLTDASSLRRWIDVIK-----PDEVYNLAAQSHVAVSFEIPD----YTADVVATGALR 139 ++TD +S+ ++ I+ D + N A + + + D + + R Sbjct: 57 MLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFR 116 Query: 140 LLEAVRSHTIDSGRTVKYYQAGS 162 L +AV + R + GS Sbjct: 117 LSKAVMRA-MMKKRHGRIITIGS 138 >2B4Q-A nrPDB Length = 276 Score = 32.9 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 35/206 (16%), Positives = 58/206 (28%), Gaps = 13/206 (6%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 +IAL+TG + G + + LL G V R + A + Sbjct: 30 RIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPADLSSE 89 Query: 89 YADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHT 148 A +L + D + N A S+ + V + L + Sbjct: 90 AGARRLAQALGEL--SARLDILVNNA-----GTSWGAALESYPVSGWEKVMQLNVTSVFS 142 Query: 149 IDSGRTVKYYQAGSSEMFGSTPPPQS---ETTPFHPRSPYAASKCAAHWYTVNYREAYGL 205 ++ S+E S + Y SK A H + + Sbjct: 143 CIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKELVG 202 Query: 206 FACNGILFNHESPRRGENFVTRKITR 231 N N +P R + +TR I Sbjct: 203 EHINV---NVIAPGRFPSRMTRHIAN 225 >3EZL-A nrPDB Length = 256 Score = 32.5 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 40/228 (17%), Positives = 76/228 (33%), Gaps = 29/228 (12%) Query: 24 VVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKA 83 +V ++IA +TG G G+ + + L G+ V N+ R D + Sbjct: 9 MVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVA----GCGPNSPRRVKWLEDQKALGFD 64 Query: 84 LMKLHYADLTDASSLRRWIDVIK-----PDEVYNLAAQS----HVAVSFEIPDYTADVVA 134 ++ D S ++ D +K D + N A + ++ E D Sbjct: 65 FYASE-GNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNL 123 Query: 135 TGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHW 194 T + + V ++ G + + G F + Y+ +K H Sbjct: 124 TSLFNVTKQVIDGMVERGWGRIINISSVNGQKG----------QFGQTN-YSTAKAGIHG 172 Query: 195 YTVNYREAYGLFACNGILFNHESP-RRGENFVTRKITRALGRIKVGLQ 241 +T++ + A G+ N SP G + V L +I + Sbjct: 173 FTMSLAQE---VATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIP 217 >4IIN-A nrPDB Length = 271 Score = 32.5 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 37/197 (18%), Positives = 60/197 (30%), Gaps = 14/197 (7%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K LITG + G+ + + L G +V I SN ++ A++K Sbjct: 30 KNVLITGASKGIGAEIAKTLASMGLKVW--INYRSNAEVADALKNELEEKGYKAAVIKFD 87 Query: 89 YADLTDASSLRRWIDVIK--PDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRS 146 A +D + I + N A ++ ++ V L S Sbjct: 88 AASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLT------S 141 Query: 147 HTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAYGLF 206 I +K + E + Y+ASK ++ AY Sbjct: 142 AFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTN-YSASK--GGMIAMSKSFAYE-G 197 Query: 207 ACNGILFNHESPRRGEN 223 A I FN +P E Sbjct: 198 ALRNIRFNSVTPGFIET 214 >5DBI-A nrPDB Length = 374 Score = 32.5 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 46/123 (37%), Gaps = 28/123 (22%) Query: 28 RKIALITGITGQDGSYLTEFL----LGKG-YEVHGLIRRSSNFNTQRINHIYIDPHNVNK 82 + +AL+ G+TG GS L E L G ++V+G+ RR P + K Sbjct: 4 KSVALVVGVTGIVGSSLAEVLKLPDTPGGPWKVYGVARRP-------------CPVWLAK 50 Query: 83 ALMKLHYADLTDASSLRRWIDVIK-PDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLL 141 ++ D++D + +K ++ VS+ AT +L Sbjct: 51 KPVEYIQCDVSDNQETISKLSPLKDITHIFY--------VSWIG-SEDCQTNATMFKNIL 101 Query: 142 EAV 144 +V Sbjct: 102 NSV 104 >2YV2-A nrPDB Length = 297 Score = 32.1 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 21/35 (60%) Query: 22 STVVEPRKIALITGITGQDGSYLTEFLLGKGYEVH 56 + +V+ L+ GITG++GS+ + +L G +V Sbjct: 7 AVLVDSETRVLVQGITGREGSFHAKAMLEYGTKVV 41 >3VZS-A nrPDB Length = 257 Score = 32.1 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 47/144 (32%), Gaps = 15/144 (10%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 ++IA +TG G G+ + + L G+ V N+ R + + Sbjct: 14 QRIAYVTGGMGGIGTAICQRLAKDGFRVVA----GCGPNSPRREKWLEQQKALGFDFIAS 69 Query: 88 HYADLTDASSLRRWIDVIK-----PDEVYNLAAQSH--VAVSFEIPDYTA--DVVATGAL 138 ++ D S + D +K D + N A + V D+ A D T Sbjct: 70 E-GNVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLF 128 Query: 139 RLLEAVRSHTIDSGRTVKYYQAGS 162 + + V D G + S Sbjct: 129 NVTKQVIDGMADRG-WGRIVNISS 151 >3DWF-A nrPDB Length = 276 Score = 32.1 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 42/293 (14%), Positives = 87/293 (29%), Gaps = 36/293 (12%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNK-----A 83 K ++TG + G + L G V R + + + + Sbjct: 12 KKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSME 71 Query: 84 LMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEA 143 M + +A +L +D++ + V + + + +V + L A Sbjct: 72 DMTFAEEFVAEAGNLMGGLDMLILNHVL-YNRLTFFHGEIDNVRKSMEVNFHSFVVLSVA 130 Query: 144 VRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAY 203 + S ++ S + G P +PY+ASK A + R + Sbjct: 131 AMPMLMQSQGSIAVV----SSVAGKITYPL--------IAPYSASKFALDGFFSTLRSEF 178 Query: 204 GLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTK-LFLGNLQASR-DWGFAGDY 261 + N + + + + L + A R D + Y Sbjct: 179 LVNKVNVSITLCILGLIDTETAIKATSGIYLGPASPKEECALEIIKGTALRQDEMY---Y 235 Query: 262 VEAMWLMLQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEIDQRYFR 314 V + W+ Y++ +EE + NW + + ++ Y R Sbjct: 236 VGSRWV--------PYLLGNPGRKIMEELSAAEY-----NWDNVLSNEKLYGR 275 >3F9I-A nrPDB Length = 249 Score = 32.1 bits (71), Expect = 0.45, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 36/104 (34%), Gaps = 10/104 (9%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K +LITG + GS + L G +V S N +++ + N K + Sbjct: 15 KTSLITGASSGIGSAIARLLHKLGSKVII-----SGSNEEKLKSLG----NALKDNYTIE 65 Query: 89 YADLTDASSLRRWIDVI-KPDEVYNLAAQSHVAVSFEIPDYTAD 131 +L + I D + A + ++ + D D Sbjct: 66 VCNLANKEECSNLISKTSNLDILVCNAGITSDTLAIRMKDQDFD 109 >2Q2Q-A nrPDB Length = 255 Score = 31.7 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 37/108 (34%), Gaps = 13/108 (12%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K AL+TG T G + + L G ++ + I H Sbjct: 5 KTALVTGSTSGIGLGIAQVLARAGA---NIVLNGFGDPAPALAEIARHGVKAVH-----H 56 Query: 89 YADLTDASSLRRWIDVIK-----PDEVYNLAAQSHVAVSFEIPDYTAD 131 ADL+D + + + + D + N A HVA + P + D Sbjct: 57 PADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWD 104 >1OOE-A nrPDB Length = 236 Score = 31.7 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 27/174 (15%), Positives = 47/174 (27%), Gaps = 23/174 (13%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 ++ G G GS + EF GY V + S+N + + + + L Sbjct: 3 SGKVIVYGGKGALGSAILEFFKKNGYTVLNIDL-SANDQADSNILVDGNKNWTEQEQSIL 61 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSH 147 + + D V+ +A S D+ + ++ Sbjct: 62 --------EQTASSLQGSQVDGVFCVAGGWA-GGSASSKDFVKNADLM--------IKQS 104 Query: 148 TIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSP---YAASKCAAHWYTVN 198 S K A + G P Y +K A H T + Sbjct: 105 VWSSAIAAKL--ATTHLKPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSS 156 >1BDB-A nrPDB Length = 277 Score = 31.7 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 24/150 (16%), Positives = 49/150 (32%), Gaps = 24/150 (16%) Query: 31 ALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYA 90 LITG G L + + +G +V L + + +R+ + D H N + Sbjct: 8 VLITGGASGLGRALVDRFVAEGAKVAVLDK-----SAERLAELETD-HGDNVLGIVGDVR 61 Query: 91 DLTDASSLR-RWIDVI-KPDEVYNLAA------------QSHVAVSFEIPDYTADVVATG 136 L D R + K D + A + + +F+ + G Sbjct: 62 SLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDE---VFHINVKG 118 Query: 137 ALRLLEAVRSHTIDSGRTVKYYQAGSSEMF 166 + ++A + S V + ++ + Sbjct: 119 YIHAVKACLPALVASRGNV-IFTISNAGFY 147 >5WQO-A nrPDB Length = 234 Score = 31.7 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 32/176 (18%), Positives = 55/176 (31%), Gaps = 19/176 (10%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNF------NTQRINHIYIDPHNVNKA 83 LI G + G L + L +G +V + RR + + ++N+ Sbjct: 8 NVLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQH 67 Query: 84 LMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEA 143 ++ + R I +Y Q + E A LRL A Sbjct: 68 DCAERIGEMLGERRIDRLIVNA---GIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARA 124 Query: 144 VRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNY 199 + + G V + + + S S T P Y ASK A + ++ Sbjct: 125 LSG-RVSRGGVVAFMSSQMA----SLALGLSATMPL-----YGASKAALNSLVRSW 170 >4XRR-A nrPDB Length = 456 Score = 31.7 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 22/74 (29%), Gaps = 5/74 (6%) Query: 26 EPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALM 85 EP + ++ G G+ L L G+G EV + R + + Sbjct: 12 EPSPLKVVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEP-----GL 66 Query: 86 KLHYADLTDASSLR 99 DL L Sbjct: 67 AGAVRDLAATGRLT 80 >4HP8-A nrPDB Length = 247 Score = 31.7 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 56/262 (21%), Positives = 81/262 (30%), Gaps = 37/262 (14%) Query: 25 VEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKAL 84 +E RK AL+TG G + L G EV RR+ + + ++ I D N + L Sbjct: 7 LEGRK-ALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPD---ETLDIIAKDGGNASALL 62 Query: 85 MKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFE----IPDYTADVVATGALRL 140 + D D + + D + N A A S E D DV Sbjct: 63 I-----DFADPLAAKDSFTDAGFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFT 117 Query: 141 LEAVRSHTIDSGRTVKYYQAGSSEMF-GSTPPPQSETTPFHPRSPYAASKCAAHWYTVNY 199 +A + GR+ K S F G P Y A+K T Sbjct: 118 TQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPS-----------YTAAKHGVAGLTKLL 166 Query: 200 REAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAG 259 + N N +P E T + RA + ++ G WG + Sbjct: 167 ANEWAAKGINV---NAIAPGYIETNNTEAL-RADAARNKAILERIPAGR------WGHSE 216 Query: 260 DYVEAMWLMLQQEKPDDYVVAT 281 D A + DYV Sbjct: 217 DIAGAAVFLSS--AAADYVHGA 236 >6EL3-D nrPDB Length = 381 Score = 31.3 bits (69), Expect = 0.60, Method: Composition-based stats. Identities = 33/171 (19%), Positives = 59/171 (34%), Gaps = 38/171 (22%) Query: 26 EPRK----IALITGITGQDGSYLTEFL----LGKG-YEVHGLIRRSSNFNTQRINHIYID 76 EP + +ALI G+TG G+ L E L G ++V+G+ RR Sbjct: 13 EPSQSFESVALIIGVTGIVGNSLAEILPLSDTPGGPWKVYGVARRP-------------R 59 Query: 77 PHNVNKALMKLHYADLTDASSLRRWIDVI-KPDEVYNLAAQSHVAVSFEIPDYTADVVAT 135 P + D++DA R + + V+ + + + S + + Sbjct: 60 PTWNADHPIDYIQCDVSDAEDTRSKLSPLTDVTHVFYVTWTNRESES-----ENCEANGS 114 Query: 136 GALRLLEAVRSHTIDSGRTVKYYQAGSSEMFG--------STPPPQSETTP 178 +L+A+ + + Q G+ G PP +E P Sbjct: 115 MLRNVLQAIIPYAPNLRHV--CLQTGTKHYLGPFTNVDGPRHDPPFTEDMP 163 >3V48-A nrPDB Length = 268 Score = 31.3 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 35/90 (38%), Gaps = 8/90 (8%) Query: 18 PKADSTVVEPRKIALITGITGQDGSYLTEFL--LGKGYEVHGLIRRSSNFNTQRINHIYI 75 P AD+ VV LI+G+ G GSY L L + Y+V +R + N + Y Sbjct: 11 PYADAPVV-----VLISGLGG-SGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYS 64 Query: 76 DPHNVNKALMKLHYADLTDASSLRRWIDVI 105 + L A + + + + + Sbjct: 65 IAQMAAELHQALVAAGIEHYAVVGHALGAL 94 >3K8Z-A nrPDB Length = 423 Score = 31.3 bits (69), Expect = 0.76, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 44/117 (37%), Gaps = 10/117 (8%) Query: 7 GSRSDSESITAPKADSTVVEPRKIA--------LITGITGQDGSYLTEFLLGKGYEVHGL 58 G ES TA + E K ++ G GSYL +F+ G +V G+ Sbjct: 190 GGSHGRESATAKGVTICIKEAAKKRGIDIKGARVVVQGFGNAGSYLAKFMHDAGAKVVGI 249 Query: 59 IR-RSSNFNTQRINHIYIDPHNVNKALMKLHYAD-LTDASSLRRWIDVIKPDEVYNL 113 ++ + ++ Y+ + + + D +T+ L D++ P + N Sbjct: 250 SDAYGGLYDPEGLDIDYLLDRRDSFGTVTKLFNDTITNQELLELDCDILVPAAIENQ 306 >6QX9-4B nrPDB Length = 522 Score = 31.3 bits (69), Expect = 0.77, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 22/73 (30%), Gaps = 5/73 (6%) Query: 273 KPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVE-IDQRYFRPAEVDNLQG----DASK 327 P+ Y +AT G + D+ + + F P + L + +K Sbjct: 416 SPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAK 475 Query: 328 AKEVLGWKPQVGF 340 GW P Sbjct: 476 IWTHPGWSPLKTL 488 >4Z9Y-A nrPDB Length = 253 Score = 31.0 bits (68), Expect = 0.91, Method: Composition-based stats. Identities = 41/259 (15%), Positives = 77/259 (29%), Gaps = 35/259 (13%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIY--IDPHNVNKALMK 86 K+ALITG G + L G ++ G+ +++ + + + + Sbjct: 11 KVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRFLSLTADMSNVS 70 Query: 87 LHYADLTDASSLRRWIDVI-KPDEVYNLAA----QSHVAVSFEIPDYTADVVATGALRLL 141 H A + + + D + N A + + S + D ++ + Sbjct: 71 GH------AELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFFMS 124 Query: 142 EAVRSHTIDSGRTVKYYQAGSSEMF-GSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYR 200 + V I G+ K S F G P Y ASK A T Sbjct: 125 QTVARQFIKQGKGGKIINIASMLSFQGGIRVPS-----------YTASKSAVMGVTRLMA 173 Query: 201 EAYGLFACNGI-------LFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASR 253 + N N+ R + +++I + + GL L + Sbjct: 174 NEWAKHGINVNAIAPGYMATNNTQQLRADEERSKEILDRIPAGRWGLPQDLM---GPSVF 230 Query: 254 DWGFAGDYVEAMWLMLQQE 272 A DY+ + + Sbjct: 231 LASSASDYINGYTIAVDGG 249 >3EMK-A nrPDB Length = 246 Score = 31.0 bits (68), Expect = 0.91, Method: Composition-based stats. Identities = 41/252 (16%), Positives = 76/252 (30%), Gaps = 40/252 (15%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 + AL+TG TG G + L +G V +++ + + + + Sbjct: 8 RKALVTGATGGLGEAIARALHAQGAIV-----GLHGTREEKLKELAAE----LGERIFVF 58 Query: 89 YADLTDASSLRRWIDVIK-----PDEVYNLAAQS----HVAVSFEIPDYTADVVATGALR 139 A+L+D +++ + D + N A + V +S E D V T Sbjct: 59 PANLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFN 118 Query: 140 LLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNY 199 L + +H + R + S + G T P Y ASK ++ + Sbjct: 119 LTREL-THPMMRRRNGRIINITS--IVGVTGNPGQAN--------YCASKAGLIGFSKSL 167 Query: 200 REAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGLQTKLFLGNLQASRDWGFAG 259 + I A+ Q +GN+ R A Sbjct: 168 AQEIASRNVTVNC-----------IAPGFIESAMTGKLNEKQKDAIMGNIPMKRMGVGAD 216 Query: 260 DYVEAMWLMLQQ 271 ++L + Sbjct: 217 IAAAVVYLASDE 228 >3E9N-A nrPDB Length = 245 Score = 31.0 bits (68), Expect = 0.92, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 36/89 (40%), Gaps = 10/89 (11%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 +KIA++TG TG G + + L + + V+ L R H+ ++ Sbjct: 5 KKIAVVTGATGGMGIEIVKD-LSRDHIVYALGRNP--------EHLAALAEIEGVEPIES 55 Query: 88 HYA-DLTDASSLRRWIDVIKPDEVYNLAA 115 ++ + + + ++ D + + AA Sbjct: 56 DIVKEVLEEGGVDKLKNLDHVDTLVHAAA 84 >6HRD-A nrPDB Length = 317 Score = 30.6 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 19/109 (17%), Positives = 29/109 (26%), Gaps = 11/109 (10%) Query: 36 ITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYA----- 90 GQ GS + E G EV + R + V+ + Sbjct: 32 GAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLERAVSAGKVTERERDRALG 91 Query: 91 ------DLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVV 133 DL D S + I+ + DE + + PD Sbjct: 92 LLTFTTDLNDLSDRQLVIEAVVEDEAVKSEIFAELDRVVTDPDAVLASN 140 >1O89-A nrPDB Length = 345 Score = 30.2 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 22/66 (33%), Gaps = 2/66 (3%) Query: 21 DSTVVEPRKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNV 80 D+ V ++TG +G GS L GY+V + R S + + Sbjct: 161 DAGVRPQDGEIVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEY--LKSLGASRVLP 218 Query: 81 NKALMK 86 + Sbjct: 219 RDEFAE 224 >3H0K-A nrPDB Length = 178 Score = 30.2 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 16/32 (50%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIR 60 K+ LITG+ G S + L +G +V + Sbjct: 1 KVILITGMPGSGKSEFAKLLKERGAKVIVMSD 32 >3LYL-A nrPDB Length = 247 Score = 30.2 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 37/95 (38%), Gaps = 11/95 (11%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKAL-MKL 87 K+AL+TG + G + L KG V G T + + + K + Sbjct: 6 KVALVTGASRGIGFEVAHALASKGATVVG-------TATSQASAEKFENSMKEKGFKARG 58 Query: 88 HYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVS 122 +++D S++ + IK + NLA V + Sbjct: 59 LVLNISDIESIQNFFAEIKAE---NLAIDILVNNA 90 >4FQE-A nrPDB Length = 222 Score = 30.2 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 29/160 (18%), Positives = 58/160 (36%), Gaps = 13/160 (8%) Query: 161 GSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAY--GLFACNGILFNHESP 218 S + + ++ PF+ + A++ Y N + G +G N+ P Sbjct: 34 SSEVKWAQSSADKTPNKPFNEQVSNGTEVVASYVYKFNSVFSIEPGFSLESGSSNNNYRP 93 Query: 219 R-RGENFVTRKITRALGRIKVGLQTKLFLGNLQASR---------DWGFAGDYVEAMWLM 268 RG VT ++ AL + +G D+ F DY L Sbjct: 94 YLRGRANVTDDLSVALRYRPYFKRNSGNIGKDNTMDKGYTLTGNIDYTFLKDYTIGYELE 153 Query: 269 LQQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDYVEI 308 ++ +++ + + + + +S+ + NWK YVE+ Sbjct: 154 YKKGTSGKTILSDNDDYDITHNVKLSYKW-DKNWKPYVEV 192 >1HXH-A nrPDB Length = 253 Score = 30.2 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 17/27 (62%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEV 55 K+AL+TG G + + LLG+G +V Sbjct: 7 KVALVTGGASGVGLEVVKLLLGEGAKV 33 >5NR1-A nrPDB Length = 228 Score = 29.8 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 21/157 (13%), Positives = 48/157 (30%), Gaps = 15/157 (9%) Query: 123 FEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPR 182 +E+P + +G +L +++ + + ++E P R Sbjct: 38 WEMPPEFTSLNPSGMPPVL-------VETKHQRNLVICETRAILEHIEETETEP-PLLGR 89 Query: 183 SPY--AASKCAAHWYTVNYREAYGLFACNGILFNHESPRRGENFVTRKITRALGRIKVGL 240 P A ++ W+ + F + + + + R R+ +G Sbjct: 90 DPAERAEARRLLQWFDRKFDNEVNGFLLHEKMEKRLLRMGAPDLAALRQGREALRMHLG- 148 Query: 241 QTKLFLGNLQASRDWGFAGDYVEAMWLMLQQEKPDDY 277 ++ +L +RDW A + DY Sbjct: 149 ----YIESLLQTRDWLAGRRMSLADFAAAAHLSVIDY 181 >2GU2-A nrPDB Length = 312 Score = 29.8 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 34/104 (32%), Gaps = 7/104 (6%) Query: 26 EPRKIALITGITG---QDGSYLTEFLLGKGYEVH--GLIRRSSNFNTQRINHIYIDPHNV 80 EP K I G T G +L L G EVH GL + N + + Sbjct: 8 EPIKKIAIFGGTHGNELTGVFLVTHWLKNGAEVHRAGLEVKPFITNPRAVEKCTRYIDCD 67 Query: 81 NKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFE 124 + L + L + + E+ +L + +++ Sbjct: 68 LNRVFDLENLSKEMSEDLPYEVRRAQ--EINHLFGPKNSDDAYD 109 >5YSS-A nrPDB Length = 256 Score = 29.8 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 35/110 (31%), Gaps = 18/110 (16%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K AL+TG T G + + L G + + + P H Sbjct: 6 KTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPG--------YH 57 Query: 89 YADLTDASSLRRWIDVIK-----PDEVYNLAAQSHVAVSFEIPDYTADVV 133 ADL+D + + + + D + N A HV P T V Sbjct: 58 GADLSDEAQIADMMRYAESEFGGVDILINNAGIQHV-----SPIETFPVD 102 >2ZCU-A nrPDB Length = 286 Score = 29.8 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 30/172 (17%), Positives = 53/172 (30%), Gaps = 30/172 (17%) Query: 33 ITGITGQDGSYLTEFLLGK--GYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYA 90 ITG TGQ G Y+ E L+ ++ ++R + + + + A Sbjct: 4 ITGATGQLGHYVIESLMKTVPASQIVAIVRNPA------------KAQALAAQGITVRQA 51 Query: 91 DLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTID 150 D D ++L + V L S V P + + A ++ + Sbjct: 52 DYGDEAALTSAL-----QGVEKLLLISSSEVGQRAPQHRNVIN---------AAKAAGVK 97 Query: 151 SGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREA 202 A +S + ET S + WY+ NY + Sbjct: 98 FIAYTSLLHADTSPL--GLADEHIETEKMLADSGIVYTLLRNGWYSENYLAS 147 >2O23-A nrPDB Length = 265 Score = 29.4 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 38/130 (29%), Gaps = 24/130 (18%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHY 89 +A+ITG G E L+G+G L +S Q Sbjct: 14 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---------GNNCVFAP 64 Query: 90 ADLTDASSLRRWIDVIK-----PDEVYNLAAQSHVAVSFEIPDYTADV----------VA 134 AD+T ++ + + K D N A + + ++ + Sbjct: 65 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 124 Query: 135 TGALRLLEAV 144 G ++ V Sbjct: 125 MGTFNVIRLV 134 >1P33-A nrPDB Length = 289 Score = 29.4 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 20/38 (52%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNT 67 +AL+TG + GS + E L +GY V RS+ + Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADAS 46 >4RZH-A nrPDB Length = 247 Score = 29.0 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 39/226 (17%), Positives = 74/226 (32%), Gaps = 25/226 (11%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 ++AL+TG + G L G +V +SS + I + + Sbjct: 7 QVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQANVA 66 Query: 89 YADLTDASSLRRWIDVI-KPDEVYNLAAQS----HVAVSFEIPDYTADVVATGALRLLEA 143 AD D ++ +D + D + N A + + + E D+ TG +A Sbjct: 67 NADEVD-QLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCTKA 125 Query: 144 VRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAY 203 V + ++ + S + G P Y+A+K +T + Sbjct: 126 VSKLMLK-QKSGRIINITS--VAGMMGNPGQAN--------YSAAKAGVIGFTKTVAKE- 173 Query: 204 GLFACNGILFNHESP-----RRGENFVTRKITRALGRIKVGLQTKL 244 A G+ N +P EN I + + + G ++ Sbjct: 174 --LASRGVTVNAVAPGFIATDMTENLNAEPILQFIPLARYGQPEEV 217 >2DKN-A nrPDB Length = 255 Score = 29.0 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 15/31 (48%) Query: 30 IALITGITGQDGSYLTEFLLGKGYEVHGLIR 60 + ITG G+ L E L G+ V G+ R Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDR 33 >5GXF-A nrPDB Length = 330 Score = 29.0 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 31/85 (36%), Gaps = 9/85 (10%) Query: 31 ALITGITGQDGSYLTEFLLGKGYEVHGLIRR-------SSNFNTQRINHIYIDPHNVNKA 83 L+TG G GS T L GYEV + R +S TQ + I+ Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETADYLTSLGATQIVARDEINETVKRPL 212 Query: 84 LMKLHYA--DLTDASSLRRWIDVIK 106 ++ D + L R + +K Sbjct: 213 ESEIWAGCVDAVGGAMLARVLGQMK 237 >4FC7-A nrPDB Length = 277 Score = 29.0 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 37/121 (30%), Gaps = 14/121 (11%) Query: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 K+A ITG G + E + G R T M Sbjct: 28 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM--- 84 Query: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAAQSHV----AVSFEIPDYTADVVATGALR 139 D+ ++ +D + D + N AA + + A+SF D+ +G Sbjct: 85 --DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 142 Query: 140 L 140 + Sbjct: 143 V 143 >3K44-A nrPDB Length = 146 Score = 29.0 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 9/56 (16%), Positives = 20/56 (35%), Gaps = 7/56 (12%) Query: 148 TIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNYREAY 203 + + + + + S+ + S PP ++ P K + +YR Y Sbjct: 47 ALSTAAEFRDHLSSFSDYYASLGPPNTDNLPEDG-------KLKSEMMIKDYRRYY 95 >4UUM-A nrPDB Length = 341 Score = 28.6 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 8/18 (44%), Positives = 11/18 (61%) Query: 31 ALITGITGQDGSYLTEFL 48 LITG GQ G L+ ++ Sbjct: 7 VLITGAAGQIGYILSHWI 24 >4IIV-A nrPDB Length = 267 Score = 28.6 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 20/144 (13%), Positives = 44/144 (30%), Gaps = 14/144 (9%) Query: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 + L+TG + G + L G+ + R + + +N I N +L Sbjct: 26 SRSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAI-----VANGGNGRL 80 Query: 88 HYADLTDASSLRRWIDVIKPDE-----VYNLAA----QSHVAVSFEIPDYTADVVATGAL 138 D+ + R ++ V + A + A+S + D Sbjct: 81 LSFDVANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFY 140 Query: 139 RLLEAVRSHTIDSGRTVKYYQAGS 162 +++ I + + + S Sbjct: 141 NVIQPCIMPMIGARQGGRIITLSS 164 >1VCN-A nrPDB Length = 550 Score = 28.6 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 15/43 (34%), Gaps = 6/43 (13%) Query: 27 PRKIALITGIT------GQDGSYLTEFLLGKGYEVHGLIRRSS 63 PRK ITG G S L L +GY V + Sbjct: 11 PRKYVFITGGVVSSLGKGILTSSLGALLRARGYRVTAIKIDPY 53 >5GUP-v nrPDB Length = 453 Score = 27.5 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 28/100 (28%), Gaps = 4/100 (4%) Query: 58 LIRRSSNFNTQRINHIYIDPHNVNKALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQS 117 + R S + + A + L DL R + + + N A S Sbjct: 4 ITRAGSFSRFYSLKVAPKALASAAPAGVPLQPQDL----EFTRLPNGLVIASLENYAPAS 59 Query: 118 HVAVSFEIPDYTADVVATGALRLLEAVRSHTIDSGRTVKY 157 + + + D G LL S T + K Sbjct: 60 RIGLFIKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKI 99 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.120 0.300 Lambda K H 0.267 0.0366 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,972,708 Number of Sequences: 36641 Number of extensions: 436140 Number of successful extensions: 1761 Number of sequences better than 10.0: 178 Number of HSP's better than 10.0 without gapping: 111 Number of HSP's successfully gapped in prelim test: 110 Number of HSP's that attempted gapping in prelim test: 1407 Number of HSP's gapped (non-prelim): 233 length of query: 373 length of database: 10,336,785 effective HSP length: 99 effective length of query: 274 effective length of database: 6,709,326 effective search space: 1838355324 effective search space used: 1838355324 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.5 bits)