BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P80067 (462 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1JQP-A nrPDB 914 0.0 3PDF-A nrPDB 757 0.0 4OEL-A nrPDB 630 0.0 4CDF-B nrPDB 313 1e-85 3QJ3-A nrPDB 148 4e-36 1NB3-A nrPDB 145 3e-35 6CZS-A nrPDB 140 1e-33 4OEM-B nrPDB 132 4e-31 2O6X-A nrPDB 129 2e-30 3QT4-A nrPDB 121 8e-28 2PNS-A nrPDB 120 1e-27 3KFQ-A nrPDB 118 5e-27 1CPJ-A nrPDB 118 7e-27 1EF7-A nrPDB 117 1e-26 1DEU-A nrPDB 117 2e-26 4HWY-A nrPDB 116 2e-26 4P6E-A nrPDB 116 2e-26 3PBH-A nrPDB 116 2e-26 6MIS-A nrPDB 115 3e-26 3BCN-A nrPDB 115 4e-26 6BKI-A nrPDB 115 5e-26 1CJL-A nrPDB 114 6e-26 1MIR-A nrPDB 114 8e-26 3P5W-A nrPDB 114 9e-26 2B1M-A nrPDB 114 1e-25 4YYW-A nrPDB 114 1e-25 2BDZ-A nrPDB 114 1e-25 2C0Y-A nrPDB 113 2e-25 7PCK-A nrPDB 112 2e-25 3HWN-A nrPDB 112 3e-25 4I05-A nrPDB 112 3e-25 3OF9-A nrPDB 112 5e-25 5OGQ-A nrPDB 111 5e-25 3CBK-A nrPDB 110 9e-25 4BS5-A nrPDB 110 2e-24 1IWD-A nrPDB 109 2e-24 1S4V-A nrPDB 109 3e-24 4I04-A nrPDB 109 3e-24 1O0E-A nrPDB 108 4e-24 5A24-A nrPDB 108 4e-24 1CQD-A nrPDB 107 8e-24 5EF4-A nrPDB 107 9e-24 5JA7-A nrPDB 107 1e-23 3F75-A nrPDB 107 1e-23 4YYQ-A nrPDB 107 2e-23 2ACT-A nrPDB 106 2e-23 2VHS-A nrPDB 106 3e-23 3BPF-A nrPDB 105 3e-23 2CIO-A nrPDB 105 4e-23 4YYR-A nrPDB 104 6e-23 4QRX-A nrPDB 104 7e-23 1AEC-A nrPDB 103 1e-22 4PI3-A nrPDB 101 5e-22 1M6D-A nrPDB 100 1e-21 6EXO-A nrPDB 100 2e-21 3BPM-A nrPDB 100 2e-21 5VPK-A nrPDB 99 4e-21 2DCB-A nrPDB 99 4e-21 1YAL-A nrPDB 98 9e-21 5JT8-A nrPDB 97 2e-20 3U8E-A nrPDB 96 2e-20 3IOQ-A nrPDB 95 6e-20 1PCI-A nrPDB 91 9e-19 5VCN-A nrPDB 88 9e-18 1SP4-B nrPDB 86 3e-17 1CSB-B nrPDB 86 3e-17 1PPO-A nrPDB 86 3e-17 1ICF-A nrPDB 84 9e-17 1XKG-A nrPDB 84 1e-16 2FO5-A nrPDB 82 5e-16 5FPW-A nrPDB 82 7e-16 1GEC-E nrPDB 81 8e-16 5I4H-B nrPDB 64 2e-10 5I4H-A nrPDB 60 2e-09 3CH2-X nrPDB 47 3e-05 3OIS-A nrPDB 35 0.093 4K7C-A nrPDB 34 0.16 4D59-A nrPDB 33 0.20 4CI7-A nrPDB 33 0.20 2C1G-A nrPDB 30 2.8 5WDK-A nrPDB 29 5.2 4AYL-A nrPDB 29 5.3 >1JQP-A nrPDB Length = 438 Score = 914 bits (2362), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/438 (99%), Positives = 436/438 (99%) Query: 25 DTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYF 84 DTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYF Sbjct: 1 DTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYF 60 Query: 85 TLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMAN 144 TLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMAN Sbjct: 61 TLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMAN 120 Query: 145 HSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRR 204 HSEKVYVNVAHLGGLQEKYSERLYSH+HNFVKAINSVQKSWTATTY YEKLSIRDLIRR Sbjct: 121 HSEKVYVNVAHLGGLQEKYSERLYSHHHNFVKAINSVQKSWTATTYRRYEKLSIRDLIRR 180 Query: 205 SGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLG 264 SGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLG Sbjct: 181 SGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLG 240 Query: 265 MLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYT 324 MLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYT Sbjct: 241 MLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYT 300 Query: 325 ATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHS 384 ATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHS Sbjct: 301 ATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHS 360 Query: 385 GIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 GIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT Sbjct: 361 GIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 420 Query: 445 DECAIESIAMAAIPIPKL 462 DECAIESIAMAAIPIPKL Sbjct: 421 DECAIESIAMAAIPIPKL 438 >3PDF-A nrPDB Length = 441 Score = 757 bits (1954), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/439 (80%), Positives = 391/439 (89%), Gaps = 1/439 (0%) Query: 25 DTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYF 84 DTPANCTY DLLGTWVFQVG + +NCSVM P E+KVV++L+KLDTAYD++GNSG+F Sbjct: 1 DTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVVYLQKLDTAYDDLGNSGHF 60 Query: 85 TLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMAN 144 T+IYNQGFEIVLNDYKWFAFFKY+ +GS+ +YC+ETMTGWVHDVLGRNWACF GKK+ Sbjct: 61 TIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGT 120 Query: 145 HSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRR 204 SE VYVN AHL QEKYS RLY ++HNFVKAIN++QKSWTATTY EYE L++ D+IRR Sbjct: 121 ASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRR 180 Query: 205 SG-HSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASL 263 SG HS +I RPKPAP+T EIQQ+IL LP SWDWRNV GINFVSPVRNQ SCGSCYSFAS+ Sbjct: 181 SGGHSRKIPRPKPAPLTAEIQQKILFLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASM 240 Query: 264 GMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPY 323 GMLEARIRILTNNSQTPILSPQEVVSCS YAQGC+GGFPYLIAGKYAQDFG+VEE CFPY Sbjct: 241 GMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPY 300 Query: 324 TATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYH 383 T TD+PCK KE+C RYYSSEY+YVGGFYGGCNEALMKLELV HGPMAVAFEV+DDFLHY Sbjct: 301 TGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYK 360 Query: 384 SGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG 443 GIYHHTGL DPFNPFELTNHAVLLVGYG D +G+DYWIVKNSWG+ WGE+GYFRIRRG Sbjct: 361 KGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRG 420 Query: 444 TDECAIESIAMAAIPIPKL 462 TDECAIESIA+AA PIPKL Sbjct: 421 TDECAIESIAVAATPIPKL 439 >4OEL-A nrPDB Length = 370 Score = 630 bits (1624), Expect = 0.0, Method: Compositional matrix adjust. Identities = 294/369 (79%), Positives = 327/369 (88%), Gaps = 1/369 (0%) Query: 25 DTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYF 84 DTPANCTY DLLGTWVFQVG + +NCSVM P E+KVV++L+KLDTAYD++GNSG+F Sbjct: 1 DTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVVYLQKLDTAYDDLGNSGHF 60 Query: 85 TLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMAN 144 T+IYNQGFEIVLNDYKWFAFFKY+ +GS+ +YC+ETMTGWVHDVLGRNWACF GKK+ Sbjct: 61 TIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGT 120 Query: 145 HSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRR 204 SE VYVN AHL QEKYS RLY ++HNFVKAIN++QKSWTATTY EYE L++ D+IRR Sbjct: 121 ASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRR 180 Query: 205 SG-HSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASL 263 SG HS +I RPKPAP+T EIQQ+IL LP SWDWRNV GINFVSPVRNQ SCGSCYSFAS+ Sbjct: 181 SGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASM 240 Query: 264 GMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPY 323 GMLEARIRILTNNSQTPILSPQEVVSCS YAQGC+GGFPYLIAGKYAQDFG+VEE CFPY Sbjct: 241 GMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPY 300 Query: 324 TATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYH 383 T TD+PCK KE+C RYYSSEY+YVGGFYGGCNEALMKLELV HGPMAVAFEV+DDFLHY Sbjct: 301 TGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYK 360 Query: 384 SGIYHHTGL 392 GIYHHTGL Sbjct: 361 KGIYHHTGL 369 >4CDF-B nrPDB Length = 166 Score = 313 bits (801), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 146/165 (88%), Positives = 153/165 (92%) Query: 228 LSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEV 287 L LP SWDWRNV GINFVSPVRNQ SCGSCYSFAS+GMLEARIRILTNNSQTPILSPQEV Sbjct: 1 LHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEV 60 Query: 288 VSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 VSCS YAQGC+GGFPYLIAGKYAQDFG+VEE CFPYT TD+PCK KE+C RYYSSEY+YV Sbjct: 61 VSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYV 120 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGL 392 GGFYGGCNEALMKLELV HGPMAVAFEV+DDFLHY GIYHHTGL Sbjct: 121 GGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGL 165 >3QJ3-A nrPDB Length = 331 Score = 148 bits (374), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 87/227 (38%), Positives = 121/227 (53%), Gaps = 21/227 (9%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S+DWR+ VSPV+NQ SCGS ++F+S G +E++++I +S Q++V C Sbjct: 117 PASFDWRDQ---GMVSPVKNQGSCGSSWAFSSTGAIESQMKIANGAGYDSSVSEQQLVDC 173 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGF 350 P A GC GG+ AQ+ G+ E +PY D C N + S Y Y+ Sbjct: 174 VPNALGCSGGWMNDAFTYVAQNGGIDSEGAYPYEMADGNCHYDPNQVAARLSGYVYL--- 230 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTN---HAVL 407 G +E ++ + GP+AVAF+ D F Y G+Y +NP TN HAVL Sbjct: 231 -SGPDENMLADMVATKGPVAVAFDADDPFGSYSGGVY--------YNPTCETNKFTHAVL 281 Query: 408 LVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRI-RRGTDECAIESIA 453 +VGYG + G DYW+VKNSWG WG GYF+I R + C I +A Sbjct: 282 IVGYGNE--NGQDYWLVKNSWGDGWGLDGYFKIARNANNHCGIAGVA 326 >1NB3-A nrPDB Length = 220 Score = 145 bits (367), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 89/231 (38%), Positives = 128/231 (55%), Gaps = 15/231 (6%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR + NFVSPV+NQ SCGSC++F++ G LE+ + I T + L+ Q++V C Sbjct: 2 PPSMDWR--KKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLS--LAEQQLVDC 57 Query: 291 SPY--AQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVG 348 + GC GG P + G++ E+ +PY D CK + + + + V Sbjct: 58 AQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKD---VA 114 Query: 349 GFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 EA+++ + + P++ AFEV +DFL Y GIY T P + NHAVL Sbjct: 115 NITMNDEEAMVE-AVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHK--TP-DKVNHAVLA 170 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459 VGYG++ G+ YWIVKNSWG QWG +GYF I RG + C + + A IP+ Sbjct: 171 VGYGEE--NGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPL 219 >6CZS-A nrPDB Length = 335 Score = 140 bits (352), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 86/231 (37%), Positives = 124/231 (53%), Gaps = 15/231 (6%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR + NFVSPV+NQ +CGS ++F++ G LE+ I I T + L+ Q++V C Sbjct: 117 PPSVDWR--KKGNFVSPVKNQGACGSSWTFSTTGALESAIAIATGKMLS--LAEQQLVDC 172 Query: 291 SP--YAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVG 348 + GC GG P + G++ E+ +PY D CK + + + + Sbjct: 173 AQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANIT 232 Query: 349 GFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 + +E M + + P++ AFEV DF+ Y +GIY T P + NHAVL Sbjct: 233 IY----DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHK--TP-DKVNHAVLA 285 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459 VGYG+ G+ YWIVKNSWG QWG +GYF I RG + C + + A IP+ Sbjct: 286 VGYGEK--NGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPL 334 >4OEM-B nrPDB Length = 70 Score = 132 bits (331), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 59/69 (85%), Positives = 64/69 (92%) Query: 394 DPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIA 453 DPFNPFELTNHAVLLVGYG D +G+DYWIVKNSWG+ WGE+GYFRIRRGTDECAIESIA Sbjct: 1 DPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIA 60 Query: 454 MAAIPIPKL 462 +AA PIPKL Sbjct: 61 VAATPIPKL 69 >2O6X-A nrPDB Length = 310 Score = 129 bits (324), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 86/234 (36%), Positives = 129/234 (55%), Gaps = 22/234 (9%) Query: 229 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 ++P+ DWR +V+ V++Q +CGS ++F++ G +E + + N + S Q++V Sbjct: 91 AVPDKIDWRES---GYVTEVKDQGNCGSGWAFSTTGTMEGQY--MKNERTSISFSEQQLV 145 Query: 289 SCS-PYAQ-GCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYY 346 CS P+ GC GG A +Y + FG+ E+ +PYTA + C+ + + +Y Sbjct: 146 DCSRPWGNNGCGGGL-MENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGFYT 204 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAV 406 V + G +E +K + GP AVA +V DF+ Y SGIY S +P + NHAV Sbjct: 205 V---HSG-SEVELKNLVGAEGPAAVAVDVESDFMMYRSGIYQ----SQTCSPLRV-NHAV 255 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFR-IRRGTDECAIESIAMAAIPI 459 L VGYG G DYWIVKNSWG WGE GY R +R + C I S+ A++P+ Sbjct: 256 LAVGYGTQG--GTDYWIVKNSWGLSWGERGYIRMVRNRGNMCGIASL--ASLPM 305 >3QT4-A nrPDB Length = 329 Score = 121 bits (303), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 95/295 (32%), Positives = 143/295 (48%), Gaps = 34/295 (11%) Query: 166 RLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPK-PAPITDEIQ 224 ++ HN F K V S + + K + R G+ +PK P + Sbjct: 57 KIAEHNAKFEKG--EVTYSKAMNQFGDMSKEEFLAYVNR----GKAQKPKHPENLRMPYV 110 Query: 225 QQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSP 284 L S DWR+ N VS V++Q CGS +SF++ G +E ++ + + LS Sbjct: 111 SSKKPLAASVDWRS----NAVSEVKDQGQCGSSWSFSTTGAVEGQLAL--QRGRLTSLSE 164 Query: 285 QEVVSCSPY--AQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSS 342 Q ++ CS GCDGG+ A Y D+G++ E+ +PY A C R+ SS Sbjct: 165 QNLIDCSSSYGNAGCDGGW-MDSAFSYIHDYGIMSESAYPYEAQGDYC-------RFDSS 216 Query: 343 E-YYYVGGFYG--GCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPF 399 + + G+Y +E + + + GP+AVA + D+ Y G+++ N Sbjct: 217 QSVTTLSGYYDLPSGDENSLADAVGQAGPVAVAIDATDELQFYSGGLFYDQ----TCNQS 272 Query: 400 ELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFR-IRRGTDECAIESIA 453 +L NH VL+VGYG D G DYWI+KNSWGS WGESGY+R +R + C I + A Sbjct: 273 DL-NHGVLVVGYGSD--NGQDYWILKNSWGSGWGESGYWRQVRNYGNNCGIATAA 324 >2PNS-A nrPDB Length = 208 Score = 120 bits (302), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 84/229 (36%), Positives = 119/229 (51%), Gaps = 34/229 (14%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE DWR V+PV+NQ CGSC++F+++ +E+ +I T N + LS Q++V Sbjct: 1 LPEQIDWRKK---GAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGNLIS--LSEQQLVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVE-ENCFPYTATDAPCKPKENCLRYYSSEYYYVG 348 C+ GC GG ++ A +Y D G ++ E +PY A PC+ + +R + Sbjct: 56 CNKKNHGCKGG-AFVYAYQYIIDNGGIDTEANYPYKAVQGPCRAAKKVVR--------ID 106 Query: 349 GFYG--GCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHA 405 G+ G CNE +K + V P VA + F HY SGI+ S P NH Sbjct: 107 GYKGVPHCNENALK-KAVASQPSVVAIDASSKQFQHYKSGIF-----SGPCG--TKLNHG 158 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR--GTDECAIESI 452 V++VGY KD YWIV+NSWG WGE GY R++R G C I + Sbjct: 159 VVIVGYWKD------YWIVRNSWGRYWGEQGYIRMKRVGGCGLCGIARL 201 >3KFQ-A nrPDB Length = 221 Score = 118 bits (296), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 81/230 (35%), Positives = 119/230 (51%), Gaps = 20/230 (8%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP+S DWR +V+PV+NQ+ CGSC++F++ G LE ++ + LS Q +V Sbjct: 1 LPKSVDWRKK---GYVTPVKNQKQCGSCWAFSATGALEGQM--FRKTGKLVSLSEQNLVD 55 Query: 290 CS-PYA-QGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 CS P QGC+GGF ++ G+ E +PY A D CK + + + V Sbjct: 56 CSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVAQDTGFTVV 115 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHAV 406 G +ALMK + GP++VA + H F Y SGIY S + +H V Sbjct: 116 AP---GKEKALMKA-VATVGPISVAMDAGHSSFQFYKSGIYFEPDCSS-----KNLDHGV 166 Query: 407 LLVGYGKDPVTGLD--YWIVKNSWGSQWGESGYFRIRRGTDE-CAIESIA 453 L+VGYG + + YW+VKNSWG +WG +GY +I + + C I + A Sbjct: 167 LVVGYGFEGANSDNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAA 216 >1CPJ-A nrPDB Length = 260 Score = 118 bits (295), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 86/269 (31%), Positives = 129/269 (47%), Gaps = 54/269 (20%) Query: 228 LSLPESWD----WRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILS 283 ++LPES+D W N I + +R+Q SCGSC++F ++ + RI I TN +S Sbjct: 5 INLPESFDAREQWSNCPTI---AQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVS 61 Query: 284 PQEVVSCSPY--AQGCDGGFP-----------YLIAGKYAQDFGVVEENCFPYT------ 324 +++++C GC+GG+P + G Y G C PYT Sbjct: 62 AEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIG-----CLPYTIPPCEH 116 Query: 325 ---ATDAPCK-----PKEN--CLRYYSSEY-----YYVGGFYGGCNEALMKLELVKHGPM 369 PC PK N C YS+ Y Y + +E + E+ K+GP+ Sbjct: 117 HVNGARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPV 176 Query: 370 AVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWG 429 AF V DFL Y SG+Y H + HA+ ++G+G + G+ YW+V NSW Sbjct: 177 EGAFTVFSDFLTYKSGVYKHEAGD------VMGGHAIRILGWGIE--NGVPYWLVANSWN 228 Query: 430 SQWGESGYFRIRRGTDECAIESIAMAAIP 458 + WG++G+F+I RG + C IES +A IP Sbjct: 229 ADWGDNGFFKILRGENHCGIESEIVAGIP 257 >1EF7-A nrPDB Length = 242 Score = 117 bits (293), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 107/230 (46%), Gaps = 27/230 (11%) Query: 230 LPESWDWRNVRGINFVSPVRNQ---ESCGSCYSFASLGMLEARIRILTNNSQ-TPILSPQ 285 LP+SWDWRNV G+N+ S RNQ + CGSC++ AS + RI I + + +LS Q Sbjct: 1 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 60 Query: 286 EVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENC--------- 336 V+ C A C+GG L YA G+ +E C Y A D C C Sbjct: 61 NVIDCGN-AGSCEGGND-LSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKEC 118 Query: 337 --LRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSD 394 +R Y+ + VG + M E+ +GP++ + +Y GIY Sbjct: 119 HAIRNYT--LWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAE----- 171 Query: 395 PFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 + NH V + G+G G +YWIV+NSWG WGE G+ RI T Sbjct: 172 -YQDTTYINHVVSVAGWGISD--GTEYWIVRNSWGEPWGERGWLRIVTST 218 >1DEU-A nrPDB Length = 277 Score = 117 bits (292), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 82/250 (32%), Positives = 114/250 (45%), Gaps = 38/250 (15%) Query: 209 GRILRPKPAPITDEIQQQILS---LPESWDWRNVRGINFVSPVRNQ---ESCGSCYSFAS 262 GR P+P + LS LP+SWDWRNV G+N+ S RNQ + CGSC++ AS Sbjct: 20 GRTTYPRP--------HEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHAS 71 Query: 263 LGMLEARIRILTNNS-QTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCF 321 + RI I + + +LS Q V+ C A C+GG L YA G+ +E C Sbjct: 72 TSAMADRINIKRKGAWPSTLLSVQNVIDCGN-AGSCEGGND-LSVWDYAHQHGIPDETCN 129 Query: 322 PYTATDAPCKPKENC-----------LRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMA 370 Y A D C C +R Y+ + VG + M E+ +GP++ Sbjct: 130 NYQAKDQECDKFNQCGTCNEFKECHAIRNYT--LWRVGDYGSLSGREKMMAEIYANGPIS 187 Query: 371 VAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGS 430 + +Y GIY + NH V + G+G G +YWIV+NSWG Sbjct: 188 CGIMATERLANYTGGIYAE------YQDTTYINHVVSVAGWGIS--DGTEYWIVRNSWGE 239 Query: 431 QWGESGYFRI 440 WGE G+ RI Sbjct: 240 PWGERGWLRI 249 >4HWY-A nrPDB Length = 340 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 96/321 (29%), Positives = 139/321 (43%), Gaps = 56/321 (17%) Query: 174 FVKAINSVQKS-WTATTYEEYEKLSIRDLIRRSG----HSGRILRPKPAPITDEIQQQIL 228 FV +N + + W A + +++R+ R +G ++ + PK +E + Sbjct: 36 FVDRVNRLNRGIWKAKYDGVMQNITLREAKRLNGVIKKNNNASILPKRRFTEEEARAP-- 93 Query: 229 SLPESWD----WRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSP 284 LP S+D W N I + +Q +CGSC++ A+ + R + I + Sbjct: 94 -LPSSFDSAEAWPNCPTI---PQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHISAG 149 Query: 285 QEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDA-----------PCK-- 331 + CS GC+GG P A Y G+V + C PY PC Sbjct: 150 DLLACCSDCGDGCNGGDPDR-AWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQF 208 Query: 332 ----PKEN---------CLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDD 378 PK N + Y S Y + G E EL GP VAF+V++D Sbjct: 209 NFDTPKCNYTCDDPTIPVVNYRSWTSYALQG------EDDYMRELFFRGPFEVAFDVYED 262 Query: 379 FLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYF 438 F+ Y+SG+YHH L HAV LVG+G G+ YW + NSW ++WG GYF Sbjct: 263 FIAYNSGVYHHVSGQ------YLGGHAVRLVGWGTS--NGVPYWKIANSWNTEWGMDGYF 314 Query: 439 RIRRGTDECAIESIAMAAIPI 459 IRRG+ EC IE A IP+ Sbjct: 315 LIRRGSSECGIEDGGSAGIPL 335 >4P6E-A nrPDB Length = 230 Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 78/228 (34%), Positives = 120/228 (52%), Gaps = 22/228 (9%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP+S DWR +G V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V Sbjct: 7 LPDSVDWRE-KGC--VTEVKYQGSCGACWAFSAVGALEAQLKLKT--GKLVSLSAQNLVD 61 Query: 290 CSPYA---QGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYY 346 CS +GC+GGF + G+ + +PY A D C+ S+Y Sbjct: 62 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTE 121 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHA 405 + YG E ++K + GP++V + H F Y SG+Y+ + + NH Sbjct: 122 LP--YG--REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT------QNVNHG 171 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT-DECAIESI 452 VL+VGYG + G +YW+VKNSWG +GE GY R+ R + C I S Sbjct: 172 VLVVGYGD--LNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASF 217 >3PBH-A nrPDB Length = 317 Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 87/279 (31%), Positives = 132/279 (47%), Gaps = 50/279 (17%) Query: 216 PAPITDEIQQQILSLPESWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILT 274 P P + + L LP S+D R + +R+Q SCGSC++F ++ + RI I T Sbjct: 50 PKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHT 109 Query: 275 NNSQTPILSPQEVVSC--SPYAQGCDGGFP-----------YLIAGKYAQDFGVVEENCF 321 N + +S +++++C S GC+GG+P + G Y G C Sbjct: 110 NAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVG-----CR 164 Query: 322 PYT---------ATDAPC-------KPKENCLRYYSSEY-----YYVGGFYGGCNEALMK 360 PY+ + PC K + C YS Y Y + +E + Sbjct: 165 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 224 Query: 361 LELVKHGPMAVAFEVHDDFLHYHSGIYHH-TGLSDPFNPFELTNHAVLLVGYGKDPVTGL 419 E+ K+GP+ AF V+ DFL Y SG+Y H TG + HA+ ++G+G + G Sbjct: 225 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEM-------MGGHAIRILGWGVE--NGT 275 Query: 420 DYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIP 458 YW+V NSW + WG++G+F+I RG D C IES +A IP Sbjct: 276 PYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 314 >6MIS-A nrPDB Length = 215 Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 73/218 (33%), Positives = 113/218 (51%), Gaps = 29/218 (13%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 +P+S DWR+ V+ V+NQ CGSC++FAS+ +E+ +I N + LS Q+V+ Sbjct: 1 VPQSIDWRDS---GAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVS--LSEQQVLD 55 Query: 290 CSPYAQGCDGG-----FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEY 344 C+ + GC GG + ++I+ K GV +PY A CK Y + Y Sbjct: 56 CA-VSYGCKGGWINKAYSFIISNK-----GVASAAIYPYKAAKGTCKTNGVPNSAYITRY 109 Query: 345 YYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNH 404 YV N + V + P+A A + +F HY G++ + P NH Sbjct: 110 TYVQR-----NNERNMMYAVSNQPIAAALDASGNFQHYKRGVF-----TGPCG--TRLNH 157 Query: 405 AVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR 442 A++++GYG+D +G +WIV+NSWG+ WGE GY R+ R Sbjct: 158 AIVIIGYGQDS-SGKKFWIVRNSWGAGWGEGGYIRLAR 194 >3BCN-A nrPDB Length = 209 Score = 115 bits (288), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 84/233 (36%), Positives = 117/233 (50%), Gaps = 42/233 (18%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE DWR +G V P++NQ CGSC++F+++ +E+ +I T N + LS Q++V Sbjct: 1 LPEHVDWR-AKGA--VIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLIS--LSEQQLVD 55 Query: 290 CSPYAQGCDGGF-----PYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEY 344 CS GC GG+ Y+IA + G+ E +PY A PC+ + +R Sbjct: 56 CSKKNHGCKGGYFDRAYQYIIA-----NGGIDTEANYPYKAFQGPCRAAKKVVR------ 104 Query: 345 YYVGGFYG--GCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFEL 401 + G G CNE +K V P VA + F HY GI+ + P Sbjct: 105 --IDGCKGVPQCNENALK-NAVASQPSVVAIDASSKQFQHYKGGIF-----TGPCG--TK 154 Query: 402 TNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR--GTDECAIESI 452 NH V++VGYGKD YWIV+NSWG WGE GY R++R G C I + Sbjct: 155 LNHGVVIVGYGKD------YWIVRNSWGRHWGEQGYTRMKRVGGCGLCGIARL 201 >6BKI-A nrPDB Length = 215 Score = 115 bits (287), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 75/230 (32%), Positives = 117/230 (50%), Gaps = 26/230 (11%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 +P+S D+R +V+PV+NQ CGSC++F+S G LE +++ T + LSPQ +V Sbjct: 1 VPDSIDYRKK---GYVTPVKNQGQCGSCWAFSSAGALEGQLKKKT--GKLLALSPQNLVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C GC GG+ Q+ G+ E+ +PY D E+C+ +++ G Sbjct: 56 CVTENYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQD------ESCMYNAAAKAAKCRG 109 Query: 350 F----YGGCNEALMKLELVKHGPMAVAFEVH-DDFLHYHSGIYHHTGLSDPFNPFELTNH 404 + G NE +K + + GP++V+ + F Y G+Y+ D + NH Sbjct: 110 YREIPVG--NEKALKRAVARVGPISVSIDASLASFQFYSRGVYY-----DENCDRDNVNH 162 Query: 405 AVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE-CAIESIA 453 AVL+VGYG G +WI+KNSWG WG GY + R + C I ++A Sbjct: 163 AVLVVGYGTQ--KGSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMA 210 >1CJL-A nrPDB Length = 312 Score = 114 bits (286), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 97/304 (31%), Positives = 148/304 (48%), Gaps = 46/304 (15%) Query: 161 EKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPIT 220 E +++ H+F A+N+ + T EE+ ++ + L R G++ + P+ Sbjct: 39 ELHNQEYREGKHSFTMAMNA----FGDMTSEEFRQV-MNGLQNRKPRKGKVFQE---PL- 89 Query: 221 DEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTP 280 P S DWR +V+PV+NQ CGS ++F++ G LE ++ + Sbjct: 90 ------FYEAPRSVDWREK---GYVTPVKNQGQCGSSWAFSATGALEGQM--FRKTGRLI 138 Query: 281 ILSPQEVVSCS-PYA-QGCDGGFPYLIAGKYAQDFGVVE-ENCFPYTATDAPCKPKENCL 337 LS Q +V CS P +GC+GG A +Y QD G ++ E +PY AT+ CK Sbjct: 139 SLSEQNLVDCSGPEGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCK------ 191 Query: 338 RYYSSEYYYV--GGFYG--GCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGL 392 Y+ +Y GF +ALMK + GP++VA + H+ FL Y GIY Sbjct: 192 --YNPKYSVANDAGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIYF---- 244 Query: 393 SDPFNPFELTNHAVLLVGYGKDPV--TGLDYWIVKNSWGSQWGESGYFRIRRG-TDECAI 449 +P E +H VL+VGYG + G YW+VKNSWG +WG GY ++ + + C I Sbjct: 245 -EPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 303 Query: 450 ESIA 453 S A Sbjct: 304 ASAA 307 >1MIR-A nrPDB Length = 322 Score = 114 bits (286), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 85/269 (31%), Positives = 128/269 (47%), Gaps = 54/269 (20%) Query: 228 LSLPESWD----WRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILS 283 ++LPES+D W N I + +R+Q SCGS ++F ++ + RI I TN +S Sbjct: 61 INLPESFDAREQWSNCPTI---AQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVS 117 Query: 284 PQEVVSCSPY--AQGCDGGFP-----------YLIAGKYAQDFGVVEENCFPYT------ 324 +++++C GC+GG+P + G Y G C PYT Sbjct: 118 AEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIG-----CLPYTIPPCEH 172 Query: 325 ---ATDAPCK-----PKEN--CLRYYSSEY-----YYVGGFYGGCNEALMKLELVKHGPM 369 PC PK N C YS+ Y Y + +E + E+ K+GP+ Sbjct: 173 HVNGARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPV 232 Query: 370 AVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWG 429 AF V DFL Y SG+Y H + HA+ ++G+G + G+ YW+V NSW Sbjct: 233 EGAFTVFSDFLTYKSGVYKHEAGD------VMGGHAIRILGWGIE--NGVPYWLVANSWN 284 Query: 430 SQWGESGYFRIRRGTDECAIESIAMAAIP 458 + WG++G+F+I RG + C IES +A IP Sbjct: 285 ADWGDNGFFKILRGENHCGIESEIVAGIP 313 >3P5W-A nrPDB Length = 220 Score = 114 bits (285), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 80/230 (34%), Positives = 117/230 (50%), Gaps = 24/230 (10%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP+ DWR+ V +++Q CGSC++F+++ +E +I T + + LS QE+V Sbjct: 1 LPDYVDWRSS---GAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLIS--LSEQELVD 55 Query: 290 C--SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C + +GCDGGF + G+ E +PYTA + C +Y S + Y Sbjct: 56 CGRTQNTRGCDGGFMTDGFQFIINNGGINTEANYPYTAEEGQCNLDLQQEKYVSIDTYEN 115 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAV 406 + N V + P++VA E +F HY SGI+ + P +HAV Sbjct: 116 VPY----NNEWALQTAVAYQPVSVALEAAGYNFQHYSSGIF-----TGPCGT--AVDHAV 164 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR---GTDECAIESIA 453 +VGYG + G+DYWIVKNSWG+ WGE GY RI+R G +C I A Sbjct: 165 TIVGYGTEG--GIDYWIVKNSWGTTWGEEGYMRIQRNVGGVGQCGIAKKA 212 >2B1M-A nrPDB Length = 246 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 76/218 (34%), Positives = 108/218 (49%), Gaps = 18/218 (8%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 PESWDW +G+ ++ V+ Q CGS ++F++ G +EA I T N + LS QE++ C Sbjct: 3 PESWDWSK-KGV--ITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVS--LSEQELIDC 57 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKE----NCLRYYSSEYYY 346 ++GC G+ Y + G+ E +PY A D CK E + Y + Sbjct: 58 VDESEGCYNGWHYQSFEWVVKHGGIASEADYPYKARDGKCKANEIQDKVTIDNYGVQILS 117 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAV 406 +L L + P++V+ + D F Y GIY S P+ NH V Sbjct: 118 NESTESEAESSLQSFVLEQ--PISVSIDAKD-FHFYSGGIYDGGNCSSPYG----INHFV 170 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 L+VGYG + G+DYWI KNSWG WG GY RI+R T Sbjct: 171 LIVGYGSE--DGVDYWIAKNSWGEDWGIDGYIRIQRNT 206 >4YYW-A nrPDB Length = 220 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 72/220 (32%), Positives = 124/220 (56%), Gaps = 25/220 (11%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE+ DWR+ ++ P+R+Q CGSC+ F+ ++E ++I+T+ P LS QE++ Sbjct: 1 LPETVDWRSKGAVD---PIRDQGKCGSCWVFSVTVVVEGIVKIVTDT--LPSLSEQELLD 55 Query: 290 CSPYAQ--GCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYS-SEYYY 346 C+P + GC GG+ +D G+ E+ +PYTA C ++ + S Y Sbjct: 56 CAPSYKDLGCKGGWMDKAYDYIIKDRGITSESDYPYTARKGACDSRKATEVVATISSYED 115 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFL-HYHSGIYHHT-GLSDPFNPFELTNH 404 V NE +K + V + P++VA + + Y SG++ + G+++ +H Sbjct: 116 VPAD----NEDALK-KAVANQPVSVAIDASSAAVKEYSSGVFVGSCGVAN--------DH 162 Query: 405 AVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 AV++VGYG + +G++YW+V+NSWG++WGE GY ++ R T Sbjct: 163 AVVVVGYGTE--SGVNYWLVRNSWGTKWGEEGYMKLERDT 200 >2BDZ-A nrPDB Length = 214 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 73/215 (33%), Positives = 109/215 (50%), Gaps = 24/215 (11%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 PES DWR V+PV+NQ CGSC++F+++ +E +I+T Q LS QE++ C Sbjct: 2 PESIDWREK---GAVTPVKNQNPCGSCWAFSTVATIEGINKIITG--QLISLSEQELLDC 56 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGF 350 + GCDGG+ + +Y D GV E +PY C+ K+ + Y G Sbjct: 57 ERRSHGCDGGYQ-TTSLQYVVDNGVHTEREYPYEKKQGRCRAKDK----KGPKVYITGYK 111 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAVLLV 409 Y N+ + ++ + + P++V + F Y GIY ++ T+HAV V Sbjct: 112 YVPANDEISLIQAIANQPVSVVTDSRGRGFQFYKGGIYEGPCGTN-------TDHAVTAV 164 Query: 410 GYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 GYGK Y ++KNSWG WGE GY RI+R + Sbjct: 165 GYGKT------YLLLKNSWGPNWGEKGYIRIKRAS 193 >2C0Y-A nrPDB Length = 315 Score = 113 bits (282), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 77/228 (33%), Positives = 119/228 (52%), Gaps = 22/228 (9%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP+S DWR +G V+ V+ Q SCG+ ++F+++G LEA++++ T + LS Q +V Sbjct: 99 LPDSVDWRE-KGC--VTEVKYQGSCGAAWAFSAVGALEAQLKLKT--GKLVSLSAQNLVD 153 Query: 290 CSPYA---QGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYY 346 CS +GC+GGF + G+ + +PY A D C+ S+Y Sbjct: 154 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTE 213 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHA 405 + YG E ++K + GP++V + H F Y SG+Y+ + + NH Sbjct: 214 LP--YG--REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT------QNVNHG 263 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT-DECAIESI 452 VL+VGYG + G +YW+VKNSWG +GE GY R+ R + C I S Sbjct: 264 VLVVGYGD--LNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASF 309 >7PCK-A nrPDB Length = 314 Score = 112 bits (281), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 76/245 (31%), Positives = 120/245 (48%), Gaps = 25/245 (10%) Query: 218 PITDEIQQQILSLPESWDWR-----NVRGINFVSPVRNQESCGSCYSFASLGMLEARIRI 272 P++ L +PE W+ R + R +V+PV+NQ CGSC++F+S+G LE +++ Sbjct: 81 PLSHSRSNDTLYIPE-WEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 139 Query: 273 LTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKP 332 T + LSPQ +V C GC GG+ ++ G+ E+ +PY + Sbjct: 140 KT--GKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQE----- 192 Query: 333 KENCLRYYSSEYYYVGGFYG--GCNEALMKLELVKHGPMAVAFEVH-DDFLHYHSGIYHH 389 E+C+ + + G+ NE +K + + GP++VA + F Y G+Y+ Sbjct: 193 -ESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYY- 250 Query: 390 TGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE-CA 448 D + NHAVL VGYG G +WI+KNSWG WG GY + R + C Sbjct: 251 ----DESCNSDNLNHAVLAVGYGIQ--KGNKHWIIKNSWGENWGNKGYILMARNKNNACG 304 Query: 449 IESIA 453 I ++A Sbjct: 305 IANLA 309 >3HWN-A nrPDB Length = 258 Score = 112 bits (281), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 85/234 (36%), Positives = 121/234 (51%), Gaps = 31/234 (13%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR +V+PV+NQ CGSC++F++ G LE ++ + LS Q +V C Sbjct: 40 PRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQM--FRKTGRLISLSEQNLVDC 94 Query: 291 S-PYA-QGCDGGFPYLIAGKYAQDFGVVE-ENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 S P +GC+GG A +Y QD G ++ E +PY AT+ CK Y+ +Y Sbjct: 95 SGPQGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCK--------YNPKYSVA 145 Query: 348 --GGFYG--GCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELT 402 GF +ALMK + GP++VA + H+ FL Y GIY S E Sbjct: 146 NDAGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIYFEPDCSS-----EDM 199 Query: 403 NHAVLLVGYGKDPVTGLD--YWIVKNSWGSQWGESGYFRIRRG-TDECAIESIA 453 +H VL+VGYG + + YW+VKNSWG +WG GY ++ + + C I S A Sbjct: 200 DHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAA 253 >4I05-A nrPDB Length = 285 Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 81/276 (29%), Positives = 127/276 (46%), Gaps = 41/276 (14%) Query: 212 LRPKPAPITDEIQQQILSLPESWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARI 270 LR P D + +P S+D R ++ +R+Q CGSC++F ++ + R Sbjct: 17 LRRTRRPTVDHNDWNV-EIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRS 75 Query: 271 RILTNNSQTPILSPQEVVSC-SPYAQGCDGGF----------PYLIAGKYAQDFGVVEEN 319 I + Q LS +++SC GC+GG ++ G ++ E Sbjct: 76 CIQSGGKQNVELSAVDLLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPY 135 Query: 320 CFPYTATDA-----PC--------KPKENCLRYYSSEYYY-----VGGFYGGCNEALMKL 361 FP PC + K+ C + Y + Y + +E ++ Sbjct: 136 PFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQK 195 Query: 362 ELVKHGPMAVAFEVHDDFLHYHSGIYHH-TGLSDPFNPFELTNHAVLLVGYGKDPVTGLD 420 E++K+GP+ F V++DFL+Y SGIY H TG + L HA+ ++G+G + Sbjct: 196 EIMKYGPVEAGFTVYEDFLNYKSGIYKHITGET-------LGGHAIRIIGWGVE--NKAP 246 Query: 421 YWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAA 456 YW++ NSW WGE+GYFRI RG DEC+IES A Sbjct: 247 YWLIANSWNEDWGENGYFRIVRGRDECSIESEVTAG 282 >3OF9-A nrPDB Length = 221 Score = 112 bits (279), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 85/234 (36%), Positives = 122/234 (52%), Gaps = 31/234 (13%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR +V+PV+NQ CGSC++F++ G LE ++ + LS Q +V C Sbjct: 3 PRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQM--FRKTGRLISLSEQNLVDC 57 Query: 291 S-PYA-QGCDGGFPYLIAGKYAQDFGVVE-ENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 S P +GC+GG A +Y QD G ++ E +PY AT+ CK Y+ +Y Sbjct: 58 SGPQGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCK--------YNPKYSVA 108 Query: 348 G--GFYG--GCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELT 402 GF +ALMK + GP++VA + H+ FL Y GIY +P E Sbjct: 109 NDTGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIYF-----EPDCSSEDM 162 Query: 403 NHAVLLVGYGKDPVTGLD--YWIVKNSWGSQWGESGYFRIRRG-TDECAIESIA 453 +H VL+VGYG + + YW+VKNSWG +WG GY ++ + + C I S A Sbjct: 163 DHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAA 216 >5OGQ-A nrPDB Length = 254 Score = 111 bits (278), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 77/260 (29%), Positives = 123/260 (47%), Gaps = 40/260 (15%) Query: 228 LSLPESWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQE 286 + +P S+D R ++ +R+Q CGSC++F ++ + R I + Q LS + Sbjct: 1 VEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVD 60 Query: 287 VVSC-SPYAQGCDGGF----------PYLIAGKYAQDFGVVEENCFPYTATDA-----PC 330 ++SC GC+GG ++ G ++ E FP PC Sbjct: 61 LLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPC 120 Query: 331 --------KPKENCLRYYSSEYYY-----VGGFYGGCNEALMKLELVKHGPMAVAFEVHD 377 + K+ C + Y + Y + +E ++ E++K+GP+ F V++ Sbjct: 121 GSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVYE 180 Query: 378 DFLHYHSGIYHH-TGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESG 436 DFL+Y SGIY H TG + L HA+ ++G+G + YW++ NSW WGE+G Sbjct: 181 DFLNYKSGIYKHITGET-------LGGHAIRIIGWGVE--NKAPYWLIANSWNEDWGENG 231 Query: 437 YFRIRRGTDECAIESIAMAA 456 YFRI RG DEC+IES A Sbjct: 232 YFRIVRGRDECSIESEVTAG 251 >3CBK-A nrPDB Length = 266 Score = 110 bits (276), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 82/269 (30%), Positives = 126/269 (46%), Gaps = 54/269 (20%) Query: 228 LSLPESWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQE 286 L LP S+D R + +R+Q SCGS ++F ++ + RI I TN + +S ++ Sbjct: 5 LKLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEVSAED 64 Query: 287 VVSC--SPYAQGCDGGFP-----------YLIAGKYAQDFGVVEENCFPYTATDAPCKPK 333 +++C S GC+GG+P + G Y G C PY+ PC+ Sbjct: 65 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVG-----CRPYSI--PPCEAH 117 Query: 334 ENCLR-----------------------YYSSEYYYVGGFYGGCNEALMKLELVKHGPMA 370 N R Y ++Y + +E + E+ K+GP+ Sbjct: 118 VNGARPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVE 177 Query: 371 VAFEVHDDFLHYHSGIYHH-TGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWG 429 AF V+ DFL Y SG+Y H TG + HA+ ++G+G + G YW+V NSW Sbjct: 178 GAFSVYSDFLLYKSGVYQHVTGEM-------MGGHAIRILGWGVE--NGTPYWLVANSWN 228 Query: 430 SQWGESGYFRIRRGTDECAIESIAMAAIP 458 + WG++G+F+I RG D C IES +A IP Sbjct: 229 TDWGDNGFFKILRGQDHCGIESEVVAGIP 257 >4BS5-A nrPDB Length = 225 Score = 110 bits (274), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 80/235 (34%), Positives = 120/235 (51%), Gaps = 35/235 (14%) Query: 229 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 +LP++ DWR +G V+ V+ Q SCG+C++F+++G LE ++++ T + LS Q +V Sbjct: 7 TLPDTVDWRE-KGC--VTEVKYQGSCGACWAFSAVGALEGQLKLKT--GKLISLSAQNLV 61 Query: 289 SCSPYAQ----GCDGGFPYLIAGKYAQDFGVVEENC-FPYTATDAPC-----KPKENCLR 338 CS + GC GG+ A +Y D G +E + +PY A D C C R Sbjct: 62 DCSNEEKYGNKGCGGGY-MTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSR 120 Query: 339 YYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFN 397 Y + +E +K + GP++V + H F Y SG+Y DP Sbjct: 121 YIQLPF---------GDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVY-----DDPSC 166 Query: 398 PFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRI-RRGTDECAIES 451 + NH VL+VGYG + G DYW+VKNSWG +G+ GY R+ R + C I S Sbjct: 167 TGNV-NHGVLVVGYG--TLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIAS 218 >1IWD-A nrPDB Length = 215 Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 76/227 (33%), Positives = 114/227 (50%), Gaps = 35/227 (15%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP DWR+ +N ++NQ+ CGSC++F+++ +E+ +I T Q LS QE+V Sbjct: 1 LPSFVDWRSKGAVN---SIKNQKQCGSCWAFSAVAAVESINKIRT--GQLISLSEQELVD 55 Query: 290 CSPYAQGCDGG-----FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEY 344 C + GC+GG F Y+I + G+ + +PY+A CKP LR S Sbjct: 56 CDTASHGCNGGWMNNAFQYIIT-----NGGIDTQQNYPYSAVQGSCKPYR--LRVVS--- 105 Query: 345 YYVGGFYGGC--NEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFEL 401 + GF NE+ ++ + P++V E F HY SGI+ + P + Sbjct: 106 --INGFQRVTRNNESALQSAVASQ-PVSVTVEAAGAPFQHYSSGIF-----TGPCGTAQ- 156 Query: 402 TNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECA 448 NH V++VGYG +G +YWIV+NSWG WG GY + R A Sbjct: 157 -NHGVVIVGYGTQ--SGKNYWIVRNSWGQNWGNQGYIWMERNVASSA 200 >1S4V-A nrPDB Length = 229 Score = 109 bits (272), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 82/238 (34%), Positives = 122/238 (51%), Gaps = 23/238 (9%) Query: 229 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 ++P S DWR +G V+ V++Q CGSC++F+++ +E +I TN + LS QE+V Sbjct: 1 TVPASVDWRK-KGA--VTSVKDQGQCGSCWAFSTIVAVEGINQIKTN--KLVSLSEQELV 55 Query: 289 SC-SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCK-PKENCLRYYSSEYYY 346 C + QGC+GG Q G+ E +PY A D C KEN + Sbjct: 56 DCDTDQNQGCNGGLMDYAFEFIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHEN 115 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEVH-DDFLHYHSGIYHHTGLSDPFNPFELTNHA 405 V N+ L+ V + P++VA + DF Y G++ + ++ +H Sbjct: 116 VPE-----NDENALLKAVANQPVSVAIDAGGSDFQFYSEGVFTGSCGTE-------LDHG 163 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG-TDECAIESIAM-AAIPIPK 461 V +VGYG + G YW VKNSWG +WGE GY R+ RG +D+ + IAM A+ PI K Sbjct: 164 VAIVGYGT-TIDGTKYWTVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYPIKK 220 >4I04-A nrPDB Length = 323 Score = 109 bits (272), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 80/276 (28%), Positives = 126/276 (45%), Gaps = 41/276 (14%) Query: 212 LRPKPAPITDEIQQQILSLPESWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARI 270 LR P D + +P S+D R ++ +R+Q CGS ++F ++ + R Sbjct: 55 LRRTRRPTVDHNDWNV-EIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRS 113 Query: 271 RILTNNSQTPILSPQEVVSC-SPYAQGCDGGF----------PYLIAGKYAQDFGVVEEN 319 I + Q LS +++SC GC+GG ++ G ++ E Sbjct: 114 CIQSGGKQNVELSAVDLLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPY 173 Query: 320 CFPYTATDA-----PC--------KPKENCLRYYSSEYYY-----VGGFYGGCNEALMKL 361 FP PC + K+ C + Y + Y + +E ++ Sbjct: 174 PFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQK 233 Query: 362 ELVKHGPMAVAFEVHDDFLHYHSGIYHH-TGLSDPFNPFELTNHAVLLVGYGKDPVTGLD 420 E++K+GP+ F V++DFL+Y SGIY H TG + L HA+ ++G+G + Sbjct: 234 EIMKYGPVEAGFTVYEDFLNYKSGIYKHITGET-------LGGHAIRIIGWGVE--NKAP 284 Query: 421 YWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAA 456 YW++ NSW WGE+GYFRI RG DEC+IES A Sbjct: 285 YWLIANSWNEDWGENGYFRIVRGRDECSIESEVTAG 320 >1O0E-A nrPDB Length = 208 Score = 108 bits (271), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 81/229 (35%), Positives = 114/229 (49%), Gaps = 34/229 (14%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE DWR V+PV+NQ SCGSC++F+++ +E+ +I T N + LS QE+V Sbjct: 1 LPEQIDWRKK---GAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGNLIS--LSEQELVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENC-FPYTATDAPCKPKENCLRYYSSEYYYVG 348 C GC GG ++ A +Y + G ++ +PY A PC+ +S+ + Sbjct: 56 CDKKNHGCLGG-AFVFAYQYIINNGGIDTQANYPYKAVQGPCQA--------ASKVVSID 106 Query: 349 GFYGG--CNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHA 405 G+ G CNE +K + V P VA + F Y SGI+ S P NH Sbjct: 107 GYNGVPFCNEXALK-QAVAVQPSTVAIDASSAQFQQYSSGIF-----SGPCG--TKLNHG 158 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR--GTDECAIESI 452 V +VGY + YWIV+NSWG WGE GY R+ R G C I + Sbjct: 159 VTIVGYQAN------YWIVRNSWGRYWGEKGYIRMLRVGGCGLCGIARL 201 >5A24-A nrPDB Length = 222 Score = 108 bits (270), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 72/217 (33%), Positives = 105/217 (48%), Gaps = 17/217 (7%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 +P + DWR V+PV+NQ+ CG C++F+++ +E +I T + LS +++V Sbjct: 1 VPAAVDWRTA---GAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTS--LSEEQIVD 55 Query: 290 CSPYA--QGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C +GC+GG P + G+ E+ +PYTA P Y Sbjct: 56 CDTNGNDKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGG--SPGTCSASSYQPAASIT 113 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAV 406 G N + P++VA + D F Y SGIY S P N +HAV Sbjct: 114 GYQDVPANNEQALQQAAATQPISVAIDASDPSFQSYSSGIY-----SGPCN--TNLDHAV 166 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG 443 +VGYG DP +G YWIVKNSWG+ WG+ GY ++ G Sbjct: 167 TVVGYGTDPNSGNSYWIVKNSWGTSWGQEGYIWMQMG 203 >1CQD-A nrPDB Length = 221 Score = 107 bits (268), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 79/237 (33%), Positives = 115/237 (48%), Gaps = 26/237 (10%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP+S DWR V PV+NQ CGSC++F+++ +E +I+T + + LS Q++V Sbjct: 3 LPDSIDWRENGA---VVPVKNQGGCGSCWAFSTVAAVEGINQIVTGDLIS--LSEQQLVD 57 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C+ GC GG+ + G+ E +PY D C N Y V Sbjct: 58 CTTANHGCRGGWMNPAFQFIVNNGGINSEETYPYRGQDGICNSTVNAPVVSIDSYENVPS 117 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 NE ++ + V + P++V + DF Y SGI+ TG + NHA+ + Sbjct: 118 H----NEQSLQ-KAVANQPVSVTMDAAGRDFQLYRSGIF--TGSCNI-----SANHALTV 165 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTD----ECAIESIAMAAIPIPK 461 VGYG + D+WIVKNSWG WGESGY R R + +C I A+ P+ K Sbjct: 166 VGYGTE--NDKDFWIVKNSWGKNWGESGYIRAERNIENPDGKCGI--TRFASYPVKK 218 >5EF4-A nrPDB Length = 385 Score = 107 bits (268), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 77/251 (30%), Positives = 121/251 (48%), Gaps = 34/251 (13%) Query: 218 PITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNS 277 P D I + +P+ DWR N V+ V+ Q CGSC++FA++ LE I T Sbjct: 118 PNKDFIYANVTKIPDKVDWREK---NAVTDVKGQGGCGSCWAFAAVVALEGINAIRT--G 172 Query: 278 QTPILSPQEVVSCSPYAQGCDGG-----FPYLIAGKYAQDFGVVEENCFPYTATDAPCKP 332 + S Q++V C GCDGG F Y+I + G+ E +PY Sbjct: 173 KLVKFSEQQLVDCDMTNAGCDGGLMEPAFTYVI-----KHGGIAPEASYPYVGK------ 221 Query: 333 KENCLRYYSSEYYYVGGFYG--GCNEALMKLELVKHGPMAVAFEVHDDFLHYHS-GIYHH 389 +E C + + + G G +E ++ + V H P+A ++ L ++S G+Y Sbjct: 222 RETCDKAKIKDVLKIDGRQNVPGLDEEALR-KAVAHQPVATGIQLSGHGLQFYSEGVYTG 280 Query: 390 TGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAI 449 ++P NH V +VGYG++ G+ +W VKNSWG WGE GY ++RG + + Sbjct: 281 DCGTEP-------NHGVGIVGYGENE-KGIKFWTVKNSWGPTWGEKGYIHLQRGARKEGL 332 Query: 450 ESIAM-AAIPI 459 +AM ++ PI Sbjct: 333 CGVAMHSSFPI 343 >5JA7-A nrPDB Length = 223 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 74/228 (32%), Positives = 112/228 (49%), Gaps = 24/228 (10%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P+S D+R +V+PV+NQ CGS ++F+S+G LE +++ T + LSPQ +V C Sbjct: 10 PDSVDYRKK---GYVTPVKNQGQCGSSWAFSSVGALEGQLKKKT--GKLLNLSPQNLVDC 64 Query: 291 SPYAQGCDGGFPYLIAGKYAQ-DFGVVEENCFPYTATDAPC--KPKENCLRYYSSEYYYV 347 GC GG+ A +Y Q + G+ E+ +PY + C P + Sbjct: 65 VSENDGCGGGY-MTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPE 123 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVH-DDFLHYHSGIYHHTGLSDPFNPFELTNHAV 406 G NE +K + + GP++VA + F Y G+Y+ + + NHAV Sbjct: 124 G------NEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNS-----DNLNHAV 172 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE-CAIESIA 453 L VGYG G +WI+KNSWG WG GY + R + C I ++A Sbjct: 173 LAVGYGIQ--KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLA 218 >3F75-A nrPDB Length = 224 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 76/219 (34%), Positives = 110/219 (50%), Gaps = 34/219 (15%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP DWR+ RG V+PV++Q CGSC++F++ G LE + LS QE++ Sbjct: 7 LPAGVDWRS-RGC--VTPVKDQRDCGSCWAFSTTGALEGAH--CAKTGKLVSLSEQELMD 61 Query: 290 CSPYA--QGCDGG-----FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSS 342 CS Q C GG F Y++ G+ E+ +PY A D C+ ++C + Sbjct: 62 CSRAEGNQSCSGGEMNDAFQYVL-----DSGGICSEDAYPYLARDEECRA-QSCEKVVK- 114 Query: 343 EYYYVGGFYG--GCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPF 399 + GF +EA MK L K P+++A E F YH G++ + +D Sbjct: 115 ----ILGFKDVPRRSEAAMKAALAKS-PVSIAIEADQMPFQFYHEGVFDASCGTD----- 164 Query: 400 ELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYF 438 +H VLLVGYG D + D+WI+KNSWG+ WG GY Sbjct: 165 --LDHGVLLVGYGTDKESKKDFWIMKNSWGTGWGRDGYM 201 >4YYQ-A nrPDB Length = 217 Score = 107 bits (266), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 73/226 (32%), Positives = 117/226 (51%), Gaps = 31/226 (13%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE+ DWR+ +N P+RNQ CGSC++F+++ +E+ +I+T + + Sbjct: 1 LPETVDWRSKGAVN---PIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLLDCA 57 Query: 290 CSPYAQGCDGG-----FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEY 344 S GC GG F Y+I Q+ G+ ++ +PYT C+ + S Y Sbjct: 58 QSYKNLGCQGGWVNKAFEYII-----QNRGITSQSNYPYTGHKGQCRTGLASIATIDS-Y 111 Query: 345 YYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHT-GLSDPFNPFELT 402 YV NE +K V + P++VA E F Y SG++ + G++ Sbjct: 112 QYVPSN----NENALK-NAVANQPVSVAVEAAGRAFQLYKSGVFTGSCGVA--------I 158 Query: 403 NHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECA 448 +HAV+L+GYGK G+DYW+++NSWG+ WGE GY +++R + A Sbjct: 159 DHAVVLIGYGK--YNGVDYWLLRNSWGTNWGEQGYMKLQRNVAQSA 202 >2ACT-A nrPDB Length = 220 Score = 106 bits (265), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 77/234 (32%), Positives = 116/234 (49%), Gaps = 34/234 (14%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP DWR+ V +++Q CG C++F+++ +E I +T+ S LS QE++ Sbjct: 1 LPSYVDWRSA---GAVVDIKSQGECGGCWAFSAIATVEG-INKITSGSLIS-LSEQELID 55 Query: 290 C--SPYAQGCDGG-----FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSS 342 C + +GCDGG F ++I D G+ E +PYTA D C +Y + Sbjct: 56 CGRTQNTRGCDGGYITDGFQFII-----NDGGINTEENYPYTAQDGDCDVALQDQKYVTI 110 Query: 343 EYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFEL 401 + Y + N V + P++VA + D F Y SGI+ + P Sbjct: 111 DTYENVPY----NNEWALQTAVTYQPVSVALDAAGDAFKQYASGIF-----TGPCGT--A 159 Query: 402 TNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR---GTDECAIESI 452 +HA+++VGYG + G+DYWIVKNSW + WGE GY RI R G C I ++ Sbjct: 160 VDHAIVIVGYGTEG--GVDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATM 211 >2VHS-A nrPDB Length = 217 Score = 106 bits (264), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 84/232 (36%), Positives = 119/232 (51%), Gaps = 30/232 (12%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR +V+PV+NQ CG+ Y+F++ G LE ++ + LS Q +V C Sbjct: 2 PRSVDWREK---GYVTPVKNQGQCGASYAFSATGALEGQM--FRKTGRLISLSEQNLVDC 56 Query: 291 S-PYA-QGCDGGFPYLIAGKYAQDFGVVE-ENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 S P +GC+GG A +Y QD G ++ E +PY AT+ CK Y+ +Y Sbjct: 57 SGPQGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCK--------YNPKYSVA 107 Query: 348 G--GFYG--GCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELT 402 GF +ALMK + GP++VA + H+ FL Y GIY + S Sbjct: 108 NDVGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIYFSSDCS-----SSSL 161 Query: 403 NHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG-TDECAIESIA 453 NHA+L+VGYG YW+VKNSWG +WG GY ++ + + C I S A Sbjct: 162 NHAMLVVGYGFIS-NNQKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAA 212 >3BPF-A nrPDB Length = 241 Score = 105 bits (263), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 78/227 (34%), Positives = 115/227 (50%), Gaps = 32/227 (14%) Query: 233 SWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSP 292 ++DWR G V+PV++Q++CGSC++F+S+G +E++ I N T LS QE+V CS Sbjct: 21 AYDWRLHSG---VTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLIT--LSEQELVDCSF 75 Query: 293 YAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAP--CKPKENCLRYYSSEYYYVGGF 350 GC+GG + G+ + +PY +DAP C +Y Y V Sbjct: 76 KNYGCNGGLINNAFEDMIELGGICPDGDYPYV-SDAPNLCNIDRCTEKYGIKNYLSV--- 131 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVG 410 + +K L GP++++ V DDF Y GI+ + NHAV+LVG Sbjct: 132 ----PDNKLKEALRFLGPISISVAVSDDFAFYKEGIFDGE-------CGDQLNHAVMLVG 180 Query: 411 YG-KDPVTGLD-------YWIVKNSWGSQWGESGYFRIRRGTDECAI 449 +G K+ V L Y+I+KNSWG QWGE G+ I TDE + Sbjct: 181 FGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGERGFINIE--TDESGL 225 >2CIO-A nrPDB Length = 212 Score = 105 bits (262), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 42/225 (18%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 +PE DWR V+PV+NQ SCGSC++F+++ +E I+I T N S QE++ Sbjct: 1 IPEYVDWRQK---GAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQ--YSEQELLD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C + GC+GG+P+ AQ +G+ N +PY C+ +E G Sbjct: 56 CDRRSYGCNGGYPWSALQLVAQ-YGIHYRNTYPYEGVQRYCRSREK-------------G 101 Query: 350 FYGGCNEALMKLELVKHG---------PMAVAFEVH-DDFLHYHSGIYHHTGLSDPFNPF 399 Y + + +++ G P++V E DF Y GI+ P Sbjct: 102 PYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIF-----VGPCG-- 154 Query: 400 ELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 +HAV VGYG + Y ++KNSWG+ WGE+GY RI+RGT Sbjct: 155 NKVDHAVAAVGYGPN------YILIKNSWGTGWGENGYIRIKRGT 193 >4YYR-A nrPDB Length = 222 Score = 104 bits (260), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 71/221 (32%), Positives = 119/221 (53%), Gaps = 23/221 (10%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE+ DWR ++G V+P+RNQ CGSC++F+ + ++E +I+T+ + P LS Q++V Sbjct: 1 LPETVDWR-IQGA--VNPIRNQGRCGSCWAFSVVVVVEGITKIVTD--ELPSLSEQQLVD 55 Query: 290 CSPYAQ--GCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPC-KPKENCLRYYSSEYYY 346 C+ + GC GG+ ++ G+ ++ +PYTA C K + + Y + Sbjct: 56 CATSYKNLGCSGGWMTKAYDYIIKNGGITSQSNYPYTAKKGECNKDLASQIVATIDSYEH 115 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHA 405 V NE +K V + P++V E F Y SG++ + + +HA Sbjct: 116 VPRN----NENALK-NAVANQPVSVTIEAGGRAFELYKSGVFVGSCGTK-------LDHA 163 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE 446 V+ +GYG + +DYW+V+NSWG+ WGE GY +++R E Sbjct: 164 VVAIGYGSE--NDVDYWLVRNSWGTNWGERGYIKLQRNVAE 202 >4QRX-A nrPDB Length = 363 Score = 104 bits (260), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 72/228 (31%), Positives = 113/228 (49%), Gaps = 44/228 (19%) Query: 228 LSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEV 287 +++PE DWR +G V+PV+NQ SCGS ++F+++ +E+ I+I T N S QE+ Sbjct: 150 VNIPEYVDWRQ-KGA--VTPVKNQGSCGSAWAFSAVSTIESIIKIRTGNLNE--YSEQEL 204 Query: 288 VSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 + C + GC+GG+P+ AQ +G+ N +PY C+ +E Sbjct: 205 LDCDRRSYGCNGGYPWSALQLVAQ-YGIHYRNTYPYEGVQRYCRSREK------------ 251 Query: 348 GGFYGGCNEALMKLELVKHG---------PMAVAFEVH-DDFLHYHSGIYHHTGLSDPFN 397 G Y + + +++ G P++V E DF Y GI+ Sbjct: 252 -GPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIF--------VG 302 Query: 398 P-FELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 P +HAV VGYG + Y +++NSWG+ WGE+GY RI+RGT Sbjct: 303 PCGNKVDHAVAAVGYGPN------YILIRNSWGTGWGENGYIRIKRGT 344 >1AEC-A nrPDB Length = 218 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 75/234 (32%), Positives = 115/234 (49%), Gaps = 34/234 (14%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP DWR+ V +++Q CG C++F+++ +E +I+T + LS QE++ Sbjct: 1 LPSYVDWRSA---GAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLIS--LSEQELID 55 Query: 290 C--SPYAQGCDGG-----FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSS 342 C + +GC+GG F ++I + G+ E +PYTA D C +Y + Sbjct: 56 CGRTQNTRGCNGGYITDGFQFII-----NNGGINTEENYPYTAQDGECNVDLQNEKYVTI 110 Query: 343 EYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFEL 401 + Y + N V + P++VA + D F Y SGI+ + P Sbjct: 111 DTYENVPY----NNEWALQTAVTYQPVSVALDAAGDAFKQYSSGIF-----TGPCGT--A 159 Query: 402 TNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR---GTDECAIESI 452 +HAV +VGYG + G+DYWIVKNSW + WGE GY RI R G C I ++ Sbjct: 160 IDHAVTIVGYGTEG--GIDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATM 211 >4PI3-A nrPDB Length = 216 Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 77/236 (32%), Positives = 115/236 (48%), Gaps = 33/236 (13%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRI----LTNNSQTPILSPQE 286 P + DWR RG V+ V++Q CGSC++F+++G +E + + LTN LS Q Sbjct: 3 PAAVDWR-ARGA--VTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTN------LSEQM 53 Query: 287 VVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYY 346 +VSC GC GG A ++ V E N YT P E ++ + Sbjct: 54 LVSCDKTDSGCSGGLM-----NNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHT 108 Query: 347 VGGFYGG-----CNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFEL 401 VG G +EA + L +GP+AVA + ++ Y G+ E Sbjct: 109 VGATITGHVELPQDEAQIAAWLAVNGPVAVAVDA-SSWMTYTGGVMTSC-------VSEQ 160 Query: 402 TNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAI 457 +H VLLVGY + YWI+KNSW +QWGE GY RI +G+++C ++ A +A+ Sbjct: 161 LDHGVLLVGYNDSAA--VPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAV 214 >1M6D-A nrPDB Length = 214 Score = 100 bits (250), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 70/230 (30%), Positives = 109/230 (47%), Gaps = 22/230 (9%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P WDWR+ V+ V++Q CGSC++F+ G +E + N LS QE++ C Sbjct: 2 PPEWDWRSK---GAVTKVKDQGMCGSCWAFSVTGNVEGQW--FLNQGTLLSLSEQELLDC 56 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGF 350 + C GG P G+ E+ + Y C+ + Y + + Sbjct: 57 DKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCQFSAEKAKVYIQDSVELSQ- 115 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPF---ELTNHAVL 407 NE + L K GP++VA + Y H G+S P P L +HAVL Sbjct: 116 ----NEQKLAAWLAKRGPISVAINA------FGMQFYRH-GISRPLRPLCSPWLIDHAVL 164 Query: 408 LVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAI 457 LVGYG+ + + +W +KNSWG+ WGE GY+ + RG+ C + ++A +A+ Sbjct: 165 LVGYGQR--SDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAV 212 >6EXO-A nrPDB Length = 215 Score = 100 bits (248), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 70/237 (29%), Positives = 119/237 (50%), Gaps = 35/237 (14%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPI--LSPQEVV 288 P + DWR +G V+PV++Q CGSC++F+++G +E + ++ N P+ LS Q +V Sbjct: 2 PAAVDWRE-KGA--VTPVKDQGQCGSCWAFSTIGNIEGQWQVAGN----PLVSLSEQMLV 54 Query: 289 SCSPYAQGCDGG-----FPYLIAGKYAQDFGVVEENCFPYTATDAP---CKPKENCLRYY 340 SC GC GG F +++ F E +PY + + C+ + + Sbjct: 55 SCDTIDFGCGGGLMDNAFNWIVNSNGGNVF---TEASYPYVSGNGEQPQCQMNGHEIGAA 111 Query: 341 SSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFE 400 +++ + +E + L ++GP+A+A + F+ Y+ GI E Sbjct: 112 ITDHVDLPQ-----DEDAIAAYLAENGPLAIAVDATS-FMDYNGGILTSC-------TSE 158 Query: 401 LTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAI 457 +H VLLVGY + + YWI+KNSW + WGE GY RI +GT++C + +A+ Sbjct: 159 QLDHGVLLVGY--NDASNPPYWIIKNSWSNMWGEDGYIRIEKGTNQCLMNQAVSSAV 213 >3BPM-A nrPDB Length = 243 Score = 100 bits (248), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 72/223 (32%), Positives = 104/223 (46%), Gaps = 30/223 (13%) Query: 233 SWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSP 292 ++DWR G V+PV++Q CGSC++F+S+G +E++ I + S QE+V CS Sbjct: 23 AYDWRLHGG---VTPVKDQALCGSCWAFSSVGSVESQYAI--RKKALFLFSEQELVDCSV 77 Query: 293 YAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTAT-DAPCKPKENCLRYYSSEYYYVGGFY 351 GC GG+ G+ ++ +PY + C K RY Y + Sbjct: 78 KNNGCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIKSYVSI---- 133 Query: 352 GGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGY 411 + K L GP++++ DDF Y G Y + P NHAV+LVGY Sbjct: 134 ---PDDKFKEALRYLGPISISIAASDDFAFYRGGFYDGECGAAP-------NHAVILVGY 183 Query: 412 GKDPVTGLD--------YWIVKNSWGSQWGESGYFRIRRGTDE 446 G + D Y+I+KNSWGS WGE GY + TDE Sbjct: 184 GMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLE--TDE 224 >5VPK-A nrPDB Length = 223 Score = 99.0 bits (245), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 78/234 (33%), Positives = 112/234 (47%), Gaps = 24/234 (10%) Query: 228 LSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEV 287 +++P D R++R V+P+R Q CGSC++F+ + E+ N S LS QE+ Sbjct: 9 VNVPSELDLRSLR---TVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLD--LSEQEL 63 Query: 288 VSCSPYAQGCDGG-FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYY 346 V C+ GC G P I +Y Q GVVEE +PY A + C+ + N Y S Y Sbjct: 64 VDCAS-QHGCHGDTIPRGI--EYIQQNGVVEERSYPYVAREQQCR-RPNSQHYGISNYCQ 119 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEVHD--DFLHYHS-GIYHHTGLSDPFNPFELTN 403 + Y + + + H +AV + D F HY I H N ++ Sbjct: 120 I---YPPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHD------NGYQPNY 170 Query: 404 HAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAI 457 HAV +VGYG G+DYWIV+NSW + WG+SGY + G + IE I Sbjct: 171 HAVNIVGYGS--TQGVDYWIVRNSWDTTWGDSGYGYFQAGNNLMMIEQYPYVVI 222 >2DCB-A nrPDB Length = 256 Score = 99.0 bits (245), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 83/269 (30%), Positives = 122/269 (45%), Gaps = 58/269 (21%) Query: 230 LPESWD----WRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQ 285 LPES+D W N I +R+Q SCGSC++F ++ + RI I +N +S + Sbjct: 1 LPESFDAREQWPNCPTIK---EIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAE 57 Query: 286 EVVSCSPYAQGCDGG--FP-----------YLIAGKYAQDFGVVEENCFPYT-------- 324 ++++C G FP + G Y G C PY+ Sbjct: 58 DMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVG-----CRPYSIPPCEHHV 112 Query: 325 -ATDAPC-------KPKENCLRYYSSEYYYVGGFYGGC-------NEALMKLELVKHGPM 369 + PC K + C YS Y F GC NE + E+ K+GP+ Sbjct: 113 NGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHF--GCSSYSVANNEKEIMAEIYKNGPV 170 Query: 370 AVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWG 429 AF V+ DFL Y SG+Y H + HA+ ++G+G + G YW+V NSW Sbjct: 171 EGAFSVYSDFLLYKSGVYQHVSGEI------MGGHAIRILGWGVE--NGTPYWLVGNSWN 222 Query: 430 SQWGESGYFRIRRGTDECAIESIAMAAIP 458 + WG++G+F+I RG D C IES +A +P Sbjct: 223 TDWGDNGFFKILRGQDHCGIESEIVAGMP 251 >1YAL-A nrPDB Length = 218 Score = 97.8 bits (242), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 71/219 (32%), Positives = 106/219 (48%), Gaps = 32/219 (14%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P+S DWR +G V+PV+NQ +CGSC++F+++ +E +I+T N LS QE+V C Sbjct: 2 PQSIDWR-AKGA--VTPVKNQGACGSCWAFSTIATVEGINKIVTGNLLE--LSEQELVDC 56 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCK------PKENCLRYYSSEY 344 ++ GC GG+ + +Y + GV +PY A C+ PK Y Sbjct: 57 DKHSYGCKGGYQ-TTSLQYVANNGVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVP- 114 Query: 345 YYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTN 403 C + L + + P++V E F Y SG++ + + Sbjct: 115 -------SNCETSF--LGALANQPLSVLVEAGGKPFQLYKSGVFDGPCGTK-------LD 158 Query: 404 HAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR 442 HAV VGYG G +Y I+KNSWG WGE GY R++R Sbjct: 159 HAVTAVGYGTS--DGKNYIIIKNSWGPNWGEKGYMRLKR 195 >5JT8-A nrPDB Length = 333 Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 92/318 (28%), Positives = 147/318 (46%), Gaps = 32/318 (10%) Query: 148 KVYVNVAHLGGLQEKYSERL-YSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSG 206 KVY N + + E+L + HN + + ++ + +E+ SG Sbjct: 37 KVYRNAEEEARREHHFKEQLKWVEEHNGIDGVEYAINEYSDMSEQEFS-------FHLSG 89 Query: 207 HSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGML 266 K + + SLP+++DWR + + +R Q SCGSC++FA+ G+ Sbjct: 90 GGLNFTYMKMEAAKEPLINTYGSLPQNFDWRQKARL---TRIRQQGSCGSCWAFAAAGVA 146 Query: 267 EARIRILTNNSQTPILSPQEVVSCS-----PYAQ--GCDGGFPYLIAGKYAQDFGVVEEN 319 E+ I Q+ LS QE+V C+ P Q GC G+ A KY G+VEE Sbjct: 147 ESLYSI--QKQQSIELSEQELVDCTYNRYDPSYQCNGCGSGYS-TEAFKYMIRTGLVEER 203 Query: 320 CFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDD- 378 +PY C P RY+ S Y + Y +E +M + +HGP+ + ++ Sbjct: 204 NYPYNMRTQWCDPDVEGQRYHVSGYQQLR--YHSSDEDVM-YTIQQHGPVVIYMHGSNNY 260 Query: 379 FLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYF 438 F + +G+ +D + T+HAV+LVG+G V G+DYWI++NSWG+ WG GY Sbjct: 261 FRNLGNGVLRGVAYNDAY-----TDHAVILVGWG--TVQGVDYWIIRNSWGTGWGNGGYG 313 Query: 439 RIRRGTDECAIESIAMAA 456 + RG + I + A Sbjct: 314 YVERGHNSLGINNYVTYA 331 >3U8E-A nrPDB Length = 222 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 69/230 (30%), Positives = 106/230 (46%), Gaps = 28/230 (12%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR V+ V++Q +CG C++F + G +E I T + +S Q++V C Sbjct: 2 PASIDWRKK---GAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLIS--VSEQQIVDC 56 Query: 291 SPYAQGCDGG-----FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYY 345 GG F ++I + G+ + +PYT D C + Sbjct: 57 DTXXXXXXGGDADDAFRWVI-----TNGGIASDANYPYTGVDGTCDLNKPIAAR------ 105 Query: 346 YVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHA 405 + G+ N + L+ V P++V ++G G S +P + +H Sbjct: 106 -IDGYTNVPNSSSALLDAVAKQPVSVNIYTSSTSFQLYTGPGIFAGSSCSDDPATV-DHT 163 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIES 451 VL+VGYG + T DYWIVKNSWG++WG GY IRR T+ CAI++ Sbjct: 164 VLIVGYGSNG-TNADYWIVKNSWGTEWGIDGYILIRRNTNRPDGVCAIDA 212 >3IOQ-A nrPDB Length = 213 Score = 95.1 bits (235), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 72/216 (33%), Positives = 110/216 (50%), Gaps = 24/216 (11%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 +P S DWR V+PVRNQ CGSC++F+S+ +E +I+T + LS QE++ Sbjct: 1 IPTSIDWRQK---GAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLS--LSEQELLD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C + GC GGFP L A +Y + G+ +PY C+ + + + VG Sbjct: 56 CERRSYGCRGGFP-LYALQYVANSGIHLRQYYPYEGVQRQCRASQ--AKGPKVKTDGVGR 112 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 +AL++ ++ P+++ E F +Y GI+ + P +HAV Sbjct: 113 VPRNNEQALIQRIAIQ--PVSIVVEAKGRAFQNYRGGIF-----AGPCG--TSIDHAVAA 163 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 VGYG D Y ++KNSWG+ WGE GY RI+RG+ Sbjct: 164 VGYGND------YILIKNSWGTGWGEGGYIRIKRGS 193 >1PCI-A nrPDB Length = 322 Score = 91.3 bits (225), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 91/305 (29%), Positives = 140/305 (45%), Gaps = 33/305 (10%) Query: 142 MANHSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKS-WTATTYEEYEKLSIRD 200 M NH+ K Y NV ++ Y ++ N N++ N S W E+ LS + Sbjct: 26 MLNHN-KFYENVD-----EKLYRFEIFKDNLNYIDETNKKNNSYWLGLN--EFADLSNDE 77 Query: 201 LIRRSGHSGRILRPKPAPITDE--IQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCY 258 + + G ++ DE I + I++LPE+ DWR +G V+PVR+Q SCGSC+ Sbjct: 78 FNEK--YVGSLIDATIEQSYDEEFINEDIVNLPENVDWRK-KGA--VTPVRHQGSCGSCW 132 Query: 259 SFASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEE 318 +F+++ +E +I T + LS QE+V C + GC GG+P A +Y G+ Sbjct: 133 AFSAVATVEGINKIRT--GKLVELSEQELVDCERRSHGCKGGYP-PYALEYVAKNGIHLR 189 Query: 319 NCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDD 378 + +PY A C+ K+ + G NE + L + P++V E Sbjct: 190 SKYPYKAKQGTCRAKQVGGPIVKTSGV---GRVQPNNEGNL-LNAIAKQPVSVVVESKGR 245 Query: 379 -FLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGY 437 F Y GI+ + + AV V G G Y ++KNSWG+ WGE GY Sbjct: 246 PFQLYKGGIFEGPCGTK-------VDGAVTAV--GYGKSGGKGYILIKNSWGTAWGEKGY 296 Query: 438 FRIRR 442 RI+R Sbjct: 297 IRIKR 301 >5VCN-A nrPDB Length = 222 Score = 87.8 bits (216), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 70/223 (31%), Positives = 105/223 (47%), Gaps = 22/223 (9%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P D R +R V+P+R Q CGSC++F+ + E+ L +Q+ L+ QE+V C Sbjct: 11 PAEIDLRQMR---TVTPIRMQGGCGSCWAFSGVAATESAY--LAYRNQSLDLAEQELVDC 65 Query: 291 SPYAQGCDGG-FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 + GC G P I +Y Q GVV+E+ + Y A + C+ + N R+ S Y + Sbjct: 66 AS-QHGCHGDTIPRGI--EYIQHNGVVQESYYRYVAREQSCR-RPNAQRFGISNYCQI-- 119 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHD--DFLHYHSGIYHHTGLSDPFNPFELTNHAVL 407 Y + + H +AV + D F HY + N ++ HAV Sbjct: 120 -YPPNANKIREALAQTHSAIAVIIGIKDLDAFRHYDG-----RTIIQRDNGYQPNYHAVN 173 Query: 408 LVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIE 450 +VGY G+DYWIV+NSW + WG++GY D IE Sbjct: 174 IVGYSN--AQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIE 214 >1SP4-B nrPDB Length = 205 Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 42/104 (40%), Positives = 62/104 (59%), Gaps = 8/104 (7%) Query: 355 NEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKD 414 NE + E+ K+GP+ AF V+ DFL Y SG+Y H + HA+ ++G+G + Sbjct: 108 NEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEI------MGGHAIRILGWGVE 161 Query: 415 PVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIP 458 G YW+V NSW + WG++G+F+I RG D C IES +A +P Sbjct: 162 --NGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGMP 203 >1CSB-B nrPDB Length = 205 Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 47/211 (22%) Query: 282 LSPQEVVSC--SPYAQGCDGGFP-----------YLIAGKYAQDFGVVEENCFPYT---- 324 +S +++++C S GC+GG+P + G Y G C PY+ Sbjct: 5 VSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVG-----CRPYSIPPC 59 Query: 325 -----ATDAPC-------KPKENCLRYYSSEY-----YYVGGFYGGCNEALMKLELVKHG 367 + PC K + C YS Y Y + +E + E+ K+G Sbjct: 60 EHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNG 119 Query: 368 PMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNS 427 P+ AF V+ DFL Y SG+Y H + HA+ ++G+G + G YW+V NS Sbjct: 120 PVEGAFSVYSDFLLYKSGVYQHV------TGEMMGGHAIRILGWGVE--NGTPYWLVANS 171 Query: 428 WGSQWGESGYFRIRRGTDECAIESIAMAAIP 458 W + WG++G+F+I RG D C IES +A IP Sbjct: 172 WNTDWGDNGFFKILRGQDHCGIESEVVAGIP 202 >1PPO-A nrPDB Length = 216 Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 70/214 (32%), Positives = 102/214 (47%), Gaps = 20/214 (9%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE+ DWR V+PVR+Q SCGSC++F+++ +E +I T + LS QE+V Sbjct: 1 LPENVDWRKK---GAVTPVRHQGSCGSCWAFSAVATVEGINKIRT--GKLVELSEQELVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C + GC GG+P A +Y G+ + +PY A C+ K+ + G Sbjct: 56 CERRSHGCKGGYPPY-ALEYVAKNGIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGV---G 111 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 NE + L + P++V E F Y GI+ + +HAV Sbjct: 112 RVQPNNEGNL-LNAIAKQPVSVVVESKGRPFQLYKGGIFEGPCGTK-------VDHAVTA 163 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR 442 V G G Y ++KNSWG+ WGE GY RI+R Sbjct: 164 V--GYGKSGGKGYILIKNSWGTAWGEKGYIRIKR 195 >1ICF-A nrPDB Length = 175 Score = 84.3 bits (207), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 69/190 (36%), Positives = 97/190 (51%), Gaps = 28/190 (14%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR +V+PV+NQ CGSC++F++ G LE ++ + LS Q +V C Sbjct: 2 PRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEG--QMFRKTGRLISLSEQNLVDC 56 Query: 291 S-PYA-QGCDGGFPYLIAGKYAQDFGVVE-ENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 S P +GC+GG A +Y QD G ++ E +PY AT+ CK Y+ +Y Sbjct: 57 SGPQGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCK--------YNPKYSVA 107 Query: 348 G--GFYG--GCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELT 402 GF +ALMK + GP++VA + H+ FL Y GIY S E Sbjct: 108 NDTGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIYFEPDCSS-----EDM 161 Query: 403 NHAVLLVGYG 412 +H VL+VGYG Sbjct: 162 DHGVLVVGYG 171 >1XKG-A nrPDB Length = 312 Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 69/223 (30%), Positives = 103/223 (46%), Gaps = 22/223 (9%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P D R +R V+P+R Q CGS ++F+ + E+ L Q+ L+ QE+V C Sbjct: 91 PAEIDLRQMRT---VTPIRMQGGCGSAWAFSGVAATESAY--LAYRDQSLDLAEQELVDC 145 Query: 291 SPYAQGCDGG-FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 + GC G P I +Y Q GVV+E+ + Y A + C+ + N R+ S Y + Sbjct: 146 AS-QHGCHGDTIPRGI--EYIQHNGVVQESYYRYVAREQSCR-RPNAQRFGISNYCQI-- 199 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHD--DFLHYHSGIYHHTGLSDPFNPFELTNHAVL 407 Y + + H +AV + D F HY + N ++ HAV Sbjct: 200 -YPPNANKIREALAQTHSAIAVIIGIKDLDAFRHYDG-----RTIIQRDNGYQPNYHAVN 253 Query: 408 LVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIE 450 +VGY G+DYWIV+NSW + WG++GY D IE Sbjct: 254 IVGYSN--AQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIE 294 >2FO5-A nrPDB Length = 262 Score = 82.0 bits (201), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 70/223 (31%), Positives = 103/223 (46%), Gaps = 26/223 (11%) Query: 227 ILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQE 286 + LP S DWR V+ V++Q CGSC++F+++ +E I T + + LS QE Sbjct: 1 VSDLPPSVDWRQK---GAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVS--LSEQE 55 Query: 287 VVSC-SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSE-- 343 ++ C + GC GG + G++ E +PY A C N R + Sbjct: 56 LIDCDTADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTC----NVARAAQNSPV 111 Query: 344 YYYVGGFY---GGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPF 399 ++ G E L + V + P++VA E F+ Y G++ TG Sbjct: 112 VVHIDGHQDVPANSEEDLARA--VANQPVSVAVEASGKAFMFYSEGVF--TGECG----T 163 Query: 400 ELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR 442 EL +H V +VGYG G YW VKNSWG WGE GY R+ + Sbjct: 164 EL-DHGVAVVGYGV-AEDGKAYWTVKNSWGPSWGEQGYIRVEK 204 >5FPW-A nrPDB Length = 321 Score = 81.6 bits (200), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 86/316 (27%), Positives = 131/316 (41%), Gaps = 48/316 (15%) Query: 173 NFVKAINSVQKS-WTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLP 231 FV IN + W A + + ++ + R +G + P P+ +Q LP Sbjct: 18 TFVDRINQLNGGMWKAVYNGKMQNITFAEAKRLTGAWIQKTSSLP-PVRFTEEQLRTELP 76 Query: 232 ESWD----WRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEV 287 ES+D W N I ++ +Q +C + ++ ++ ++ R + Q I + + Sbjct: 77 ESFDSAEKWPNCPTIREIA---DQSACRASWAVSTASVISDRYCTVGGVQQLRISAAHLL 133 Query: 288 VSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPY----------TATDAPC------- 330 C GC GGFP A +Y ++G+ C PY PC Sbjct: 134 SCCKQCGGGCKGGFPGF-AWRYYVEYGIASSYCQPYPFPHCEHRGAQGNKTPCSKYNFDT 192 Query: 331 -KPKENC-------LRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHY 382 K + C ++Y S Y + +G E K EL +GP F V+ D Y Sbjct: 193 PKCQATCTDKSIPLVKYRGSATYLL--LHG---EEDYKRELYFNGPFVAVFYVYTDLFAY 247 Query: 383 HSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR 442 SG+Y H + F L AV +VG+GK + G YW V N+W + WG GY I R Sbjct: 248 KSGVYRH--VDGDF----LGGTAVKVVGWGK--LNGTPYWKVANTWDTDWGMDGYLLILR 299 Query: 443 GTDECAIESIAMAAIP 458 G +EC IE + A P Sbjct: 300 GNNECNIEHLGFAGTP 315 >1GEC-E nrPDB Length = 216 Score = 81.3 bits (199), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 70/216 (32%), Positives = 104/216 (48%), Gaps = 20/216 (9%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPES DWR +G V+PV++Q C SC++F+++ +E +I T N LS QE+V Sbjct: 1 LPESVDWR-AKGA--VTPVKHQGYCESCWAFSTVATVEGINKIKTGNLVE--LSEQELVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C + GC+ G+ AQ+ G+ +PY A C+ + + G Sbjct: 56 CDLQSYGCNRGYQSTSLQYVAQN-GIHLRAKYPYIAKQQTCRANQVGGPKVKTNGV---G 111 Query: 350 FYGGCNEALMKLELVKHGPMAVAFE-VHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 NE + L + H P++V E DF +Y GI+ + + +HAV Sbjct: 112 RVQSNNEGSL-LNAIAHQPVSVVVESAGRDFQNYKGGIFEGSCGTK-------VDHAVTA 163 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 VG G Y ++KNSWG WGE+GY RIRR + Sbjct: 164 VG--YGKSGGKGYILIKNSWGPGWGENGYIRIRRAS 197 >5I4H-B nrPDB Length = 112 Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 40/102 (39%), Positives = 57/102 (55%), Gaps = 10/102 (9%) Query: 356 EALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKD 414 +ALMK + GP++VA + H+ FL Y GIY +P E +H VL+VGYG + Sbjct: 12 KALMKA-VATVGPISVAIDAGHESFLFYKEGIYF-----EPDCSSEDMDHGVLVVGYGFE 65 Query: 415 PVTGLD--YWIVKNSWGSQWGESGYFRIRRG-TDECAIESIA 453 + YW+VKNSWG +WG GY ++ + + C I S A Sbjct: 66 STESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAA 107 >5I4H-A nrPDB Length = 106 Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 40/104 (38%), Positives = 58/104 (55%), Gaps = 9/104 (8%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR +V+PV+NQ CGS ++F++ G LE ++ + LS Q +V C Sbjct: 3 PRSVDWREK---GYVTPVKNQGQCGSSWAFSATGALEG--QMFRKTGRLISLSEQNLVDC 57 Query: 291 S-PYA-QGCDGGFPYLIAGKYAQDFGVVE-ENCFPYTATDAPCK 331 S P +GC+GG A +Y QD G ++ E +PY AT+ CK Sbjct: 58 SGPQGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCK 100 >3CH2-X nrPDB Length = 265 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 7/68 (10%) Query: 400 ELTNHAVLLVGYGK---DPVTGLDYWIVKNSWGSQWGESGYFRIRR-GTDECA---IESI 452 + +HAV +VGYG YWIV+NSWG WG+ GYF++ G C I S+ Sbjct: 195 DTADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHCHFNFIHSV 254 Query: 453 AMAAIPIP 460 + + +P Sbjct: 255 VIFNVDLP 262 >3OIS-A nrPDB Length = 291 Score = 34.7 bits (78), Expect = 0.093, Method: Compositional matrix adjust. Identities = 16/35 (45%), Positives = 23/35 (65%), Gaps = 4/35 (11%) Query: 404 HAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYF 438 HAVL VGY + + ++ ++NSWG+ GE GYF Sbjct: 237 HAVLCVGYDDE----IRHFRIRNSWGNNVGEDGYF 267 >4K7C-A nrPDB Length = 446 Score = 33.9 bits (76), Expect = 0.16, Method: Compositional matrix adjust. Identities = 19/39 (48%), Positives = 23/39 (58%), Gaps = 3/39 (7%) Query: 401 LTNHAVLLVGYGKDPVTGL-DYWIVKNSWGSQWGESGYF 438 L HA++L G D V G W V+NSWG + GE GYF Sbjct: 361 LMTHAMVLTGV--DLVDGKPTKWKVENSWGEKVGEKGYF 397 >4D59-A nrPDB Length = 406 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 51/240 (21%), Positives = 94/240 (39%), Gaps = 32/240 (13%) Query: 238 NVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEV---VSCSPYA 294 N + +P +NQ S + +SF+ + LEA +++ T LS + + + Y Sbjct: 6 NPMDLGLTTPAKNQGSLNTAWSFSGMSTLEAYLKL--KGYGTYDLSEEHLRWWATGGKYG 63 Query: 295 QGCD--GGFPYLIAGKYAQDF-GVVEENCFPYT-ATDAPCKPKENCLRYYSSEYYYVGGF 350 D G + A Y + G E PY ++A K + + +++ Sbjct: 64 WNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVV 123 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVG 410 ++ +K ++++G + + + + + Y+ T P N HAV +VG Sbjct: 124 RLNKDKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLN------HAVAIVG 177 Query: 411 ----YGKDPVTGL------DYWIVKNSWGSQWGESGYFRIR-------RGTDECAIESIA 453 Y KD W+VK+SWG G+F I TD A++S++ Sbjct: 178 WDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVS 237 >4CI7-A nrPDB Length = 470 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 51/240 (21%), Positives = 94/240 (39%), Gaps = 32/240 (13%) Query: 238 NVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEV---VSCSPYA 294 N + +P +NQ S + +SF+ + LEA +++ T LS + + + Y Sbjct: 70 NPMDLGLTTPAKNQGSLNTAWSFSGMSTLEAYLKL--KGYGTYDLSEEHLRWWATGGKYG 127 Query: 295 QGCD--GGFPYLIAGKYAQDF-GVVEENCFPYT-ATDAPCKPKENCLRYYSSEYYYVGGF 350 D G + A Y + G E PY ++A K + + +++ Sbjct: 128 WNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVV 187 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVG 410 ++ +K ++++G + + + + + Y+ T P N HAV +VG Sbjct: 188 RLNKDKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLN------HAVAIVG 241 Query: 411 ----YGKDPVTGL------DYWIVKNSWGSQWGESGYFRIR-------RGTDECAIESIA 453 Y KD W+VK+SWG G+F I TD A++S++ Sbjct: 242 WDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVS 301 >2C1G-A nrPDB Length = 431 Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust. Identities = 17/62 (27%), Positives = 34/62 (54%), Gaps = 5/62 (8%) Query: 201 LIRRSGHSGRILRPKPAPITDEIQQQI-LSL----PESWDWRNVRGINFVSPVRNQESCG 255 L + G S +++RP ITD+I+ + LS +S DW++ + ++ +++Q + G Sbjct: 320 LTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDWKSKNEASILTEIQHQVANG 379 Query: 256 SC 257 S Sbjct: 380 SI 381 >5WDK-A nrPDB Length = 401 Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 396 FNPFELTN-HAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAM 454 ++ +E T+ H + + G KD G +Y++VKNSWG+ +G + + +I + Sbjct: 327 YDNYETTDDHGMQIYGIAKDQ-EGNEYYMVKNSWGTNSKYNGIWYASKAFVRYKTMNIVV 385 Query: 455 AAIPIPK 461 +PK Sbjct: 386 HKDALPK 392 >4AYL-A nrPDB Length = 246 Score = 28.9 bits (63), Expect = 5.3, Method: Compositional matrix adjust. Identities = 11/19 (57%), Positives = 13/19 (68%) Query: 343 EYYYVGGFYGGCNEALMKL 361 YYY GG GGC +A +KL Sbjct: 151 RYYYAGGLSGGCTKAYLKL 169 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1JQP-A nrPDB 705 0.0 3PDF-A nrPDB 679 0.0 4OEL-A nrPDB 567 e-162 1CJL-A nrPDB 284 5e-77 1PCI-A nrPDB 280 6e-76 3QJ3-A nrPDB 276 9e-75 4QRX-A nrPDB 275 4e-74 6CZS-A nrPDB 273 2e-73 3HWN-A nrPDB 272 3e-73 3QT4-A nrPDB 268 4e-72 1S4V-A nrPDB 266 2e-71 1NB3-A nrPDB 265 2e-71 7PCK-A nrPDB 263 9e-71 5EF4-A nrPDB 262 3e-70 3PBH-A nrPDB 261 6e-70 3KFQ-A nrPDB 259 2e-69 2C0Y-A nrPDB 258 5e-69 3P5W-A nrPDB 256 1e-68 3OF9-A nrPDB 256 2e-68 1CQD-A nrPDB 254 7e-68 2FO5-A nrPDB 251 5e-67 3BCN-A nrPDB 250 8e-67 5JA7-A nrPDB 250 1e-66 2PNS-A nrPDB 249 1e-66 4HWY-A nrPDB 249 1e-66 4P6E-A nrPDB 249 1e-66 2O6X-A nrPDB 248 3e-66 6BKI-A nrPDB 248 3e-66 4BS5-A nrPDB 248 5e-66 1AEC-A nrPDB 248 5e-66 1IWD-A nrPDB 248 6e-66 5JT8-A nrPDB 245 2e-65 1O0E-A nrPDB 245 4e-65 4YYR-A nrPDB 244 5e-65 4I04-A nrPDB 242 3e-64 2VHS-A nrPDB 241 4e-64 4YYW-A nrPDB 241 7e-64 2ACT-A nrPDB 240 9e-64 1MIR-A nrPDB 240 1e-63 3CBK-A nrPDB 240 1e-63 4I05-A nrPDB 240 1e-63 2BDZ-A nrPDB 237 7e-63 1CPJ-A nrPDB 236 1e-62 2B1M-A nrPDB 236 2e-62 6MIS-A nrPDB 235 3e-62 3F75-A nrPDB 234 8e-62 6EXO-A nrPDB 233 1e-61 2CIO-A nrPDB 233 1e-61 1YAL-A nrPDB 233 2e-61 4CDF-B nrPDB 232 2e-61 1PPO-A nrPDB 232 3e-61 5A24-A nrPDB 230 8e-61 5OGQ-A nrPDB 229 2e-60 4YYQ-A nrPDB 229 2e-60 3U8E-A nrPDB 227 9e-60 1GEC-E nrPDB 224 5e-59 4PI3-A nrPDB 220 1e-57 3BPM-A nrPDB 218 4e-57 5FPW-A nrPDB 217 9e-57 3BPF-A nrPDB 216 1e-56 3IOQ-A nrPDB 216 2e-56 1M6D-A nrPDB 213 2e-55 2DCB-A nrPDB 211 5e-55 5VPK-A nrPDB 208 4e-54 1XKG-A nrPDB 207 9e-54 1DEU-A nrPDB 204 8e-53 1ICF-A nrPDB 204 9e-53 5VCN-A nrPDB 201 6e-52 1EF7-A nrPDB 197 1e-50 1CSB-B nrPDB 170 1e-42 1SP4-B nrPDB 147 1e-35 5I4H-A nrPDB 138 4e-33 5I4H-B nrPDB 122 3e-28 4OEM-B nrPDB 118 6e-27 3CH2-X nrPDB 97 1e-20 Sequences not found previously or not previously below threshold: 4CI7-A nrPDB 74 2e-13 4D59-A nrPDB 68 7e-12 3OIS-A nrPDB 61 9e-10 4K7C-A nrPDB 42 8e-04 5WDK-A nrPDB 37 0.020 2QGM-A nrPDB 35 0.075 3X1F-A nrPDB 34 0.18 3WIA-A nrPDB 34 0.18 2CB5-A nrPDB 34 0.20 1A6R-A nrPDB 31 1.0 2Z51-A nrPDB 30 2.9 1G0D-A nrPDB 29 4.2 6G90-C nrPDB 29 5.4 >1JQP-A nrPDB Length = 438 Score = 705 bits (1819), Expect = 0.0, Method: Composition-based stats. Identities = 435/438 (99%), Positives = 436/438 (99%) Query: 25 DTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYF 84 DTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYF Sbjct: 1 DTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYF 60 Query: 85 TLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMAN 144 TLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMAN Sbjct: 61 TLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMAN 120 Query: 145 HSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRR 204 HSEKVYVNVAHLGGLQEKYSERLYSH+HNFVKAINSVQKSWTATTY YEKLSIRDLIRR Sbjct: 121 HSEKVYVNVAHLGGLQEKYSERLYSHHHNFVKAINSVQKSWTATTYRRYEKLSIRDLIRR 180 Query: 205 SGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLG 264 SGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLG Sbjct: 181 SGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLG 240 Query: 265 MLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYT 324 MLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYT Sbjct: 241 MLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYT 300 Query: 325 ATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHS 384 ATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHS Sbjct: 301 ATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHS 360 Query: 385 GIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 GIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT Sbjct: 361 GIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 420 Query: 445 DECAIESIAMAAIPIPKL 462 DECAIESIAMAAIPIPKL Sbjct: 421 DECAIESIAMAAIPIPKL 438 >3PDF-A nrPDB Length = 441 Score = 679 bits (1753), Expect = 0.0, Method: Composition-based stats. Identities = 353/439 (80%), Positives = 391/439 (89%), Gaps = 1/439 (0%) Query: 25 DTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYF 84 DTPANCTY DLLGTWVFQVG + +NCSVM P E+KVV++L+KLDTAYD++GNSG+F Sbjct: 1 DTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVVYLQKLDTAYDDLGNSGHF 60 Query: 85 TLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMAN 144 T+IYNQGFEIVLNDYKWFAFFKY+ +GS+ +YC+ETMTGWVHDVLGRNWACF GKK+ Sbjct: 61 TIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGT 120 Query: 145 HSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRR 204 SE VYVN AHL QEKYS RLY ++HNFVKAIN++QKSWTATTY EYE L++ D+IRR Sbjct: 121 ASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRR 180 Query: 205 SG-HSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASL 263 SG HS +I RPKPAP+T EIQQ+IL LP SWDWRNV GINFVSPVRNQ SCGSCYSFAS+ Sbjct: 181 SGGHSRKIPRPKPAPLTAEIQQKILFLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASM 240 Query: 264 GMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPY 323 GMLEARIRILTNNSQTPILSPQEVVSCS YAQGC+GGFPYLIAGKYAQDFG+VEE CFPY Sbjct: 241 GMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPY 300 Query: 324 TATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYH 383 T TD+PCK KE+C RYYSSEY+YVGGFYGGCNEALMKLELV HGPMAVAFEV+DDFLHY Sbjct: 301 TGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYK 360 Query: 384 SGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG 443 GIYHHTGL DPFNPFELTNHAVLLVGYG D +G+DYWIVKNSWG+ WGE+GYFRIRRG Sbjct: 361 KGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRG 420 Query: 444 TDECAIESIAMAAIPIPKL 462 TDECAIESIA+AA PIPKL Sbjct: 421 TDECAIESIAVAATPIPKL 439 >4OEL-A nrPDB Length = 370 Score = 567 bits (1461), Expect = e-162, Method: Composition-based stats. Identities = 293/368 (79%), Positives = 326/368 (88%), Gaps = 1/368 (0%) Query: 25 DTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYF 84 DTPANCTY DLLGTWVFQVG + +NCSVM P E+KVV++L+KLDTAYD++GNSG+F Sbjct: 1 DTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVVYLQKLDTAYDDLGNSGHF 60 Query: 85 TLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMAN 144 T+IYNQGFEIVLNDYKWFAFFKY+ +GS+ +YC+ETMTGWVHDVLGRNWACF GKK+ Sbjct: 61 TIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGT 120 Query: 145 HSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRR 204 SE VYVN AHL QEKYS RLY ++HNFVKAIN++QKSWTATTY EYE L++ D+IRR Sbjct: 121 ASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRR 180 Query: 205 S-GHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASL 263 S GHS +I RPKPAP+T EIQQ+IL LP SWDWRNV GINFVSPVRNQ SCGSCYSFAS+ Sbjct: 181 SGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASM 240 Query: 264 GMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPY 323 GMLEARIRILTNNSQTPILSPQEVVSCS YAQGC+GGFPYLIAGKYAQDFG+VEE CFPY Sbjct: 241 GMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPY 300 Query: 324 TATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYH 383 T TD+PCK KE+C RYYSSEY+YVGGFYGGCNEALMKLELV HGPMAVAFEV+DDFLHY Sbjct: 301 TGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYK 360 Query: 384 SGIYHHTG 391 GIYHHTG Sbjct: 361 KGIYHHTG 368 >1CJL-A nrPDB Length = 312 Score = 284 bits (727), Expect = 5e-77, Method: Composition-based stats. Identities = 87/320 (27%), Positives = 142/320 (44%), Gaps = 38/320 (11%) Query: 146 SEKVYVNVAHLGGLQ--EKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIR 203 +E+ + ++ E +++ H+F A+N+ + T EE+ ++ + L Sbjct: 22 NEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNA----FGDMTSEEFRQV-MNGLQN 76 Query: 204 RSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASL 263 R G++ + P+ P S DWR +V+PV+NQ CGS ++F++ Sbjct: 77 RKPRKGKVFQ---EPL-------FYEAPRSVDWREK---GYVTPVKNQGQCGSSWAFSAT 123 Query: 264 GMLEARIRILTNNSQTPILSPQEVVSCSP--YAQGCDGGFPYLIAGKYAQDFGVVEENCF 321 G LE ++ T LS Q +V CS +GC+GG + G+ E + Sbjct: 124 GALEGQMFRKTGR--LISLSEQNLVDCSGPEGNEGCNGGLMDYAFQYVQDNGGLDSEESY 181 Query: 322 PYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFL 380 PY AT+ CK + + + E + + GP++VA + H+ FL Sbjct: 182 PYEATEESCKYNPKYSVANDAGFVDI-----PKQEKALMKAVATVGPISVAIDAGHESFL 236 Query: 381 HYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDP--VTGLDYWIVKNSWGSQWGESGYF 438 Y GIY +P E +H VL+VGYG + G YW+VKNSWG +WG GY Sbjct: 237 FYKEGIYF-----EPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYV 291 Query: 439 RIRRG-TDECAIESIAMAAI 457 ++ + + C I S A Sbjct: 292 KMAKDRRNHCGIASAASYPT 311 >1PCI-A nrPDB Length = 322 Score = 280 bits (717), Expect = 6e-76, Method: Composition-based stats. Identities = 91/324 (28%), Positives = 141/324 (43%), Gaps = 37/324 (11%) Query: 142 MANHSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKS-WTATTYEEYEKLSIRD 200 M NH+ K Y NV ++ Y ++ N N++ N S W E+ LS + Sbjct: 26 MLNHN-KFYENVD-----EKLYRFEIFKDNLNYIDETNKKNNSYWLGLN--EFADLSNDE 77 Query: 201 LIRRSGHSGRILRPKPAPITDE--IQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCY 258 + + G ++ DE I + I++LPE+ DWR V+PVR+Q SCGSC+ Sbjct: 78 FNEK--YVGSLIDATIEQSYDEEFINEDIVNLPENVDWRKK---GAVTPVRHQGSCGSCW 132 Query: 259 SFASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEE 318 +F+++ +E +I T + LS QE+V C + GC GG+P A +Y G+ Sbjct: 133 AFSAVATVEGINKIRTG--KLVELSEQELVDCERRSHGCKGGYP-PYALEYVAKNGIHLR 189 Query: 319 NCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDD 378 + +PY A C+ K+ + G NE + L + P++V E Sbjct: 190 SKYPYKAKQGTCRAKQVGGPIVKTSGV---GRVQPNNEGNL-LNAIAKQPVSVVVESKGR 245 Query: 379 -FLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGY 437 F Y GI+ + + AV V G G Y ++KNSWG+ WGE GY Sbjct: 246 PFQLYKGGIFEGPCGTK-------VDGAVTAV--GYGKSGGKGYILIKNSWGTAWGEKGY 296 Query: 438 FRIRRGTDE----CAIESIAMAAI 457 RI+R C + + Sbjct: 297 IRIKRAPGNSPGVCGLYKSSYYPT 320 >3QJ3-A nrPDB Length = 331 Score = 276 bits (707), Expect = 9e-75, Method: Composition-based stats. Identities = 98/328 (29%), Positives = 151/328 (46%), Gaps = 24/328 (7%) Query: 133 NWACFVGKKMANHSEKVYVNVAHLGGLQ--EKYSERLYSHNHNFVKAINSVQKSWTATTY 190 N+ + N E+ + L+ E+++E+ ++ +N +T T Sbjct: 24 NFKTTYARSYVNAKEETFRKQIFQKKLETFEEHNEKYRQGLVSYTLGVNL----FTDMTP 79 Query: 191 EEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRN 250 EE + + ++ H I D + P S+DWR+ VSPV+N Sbjct: 80 EEMKAYTHGLIMPADLHKNGIPIKTRE---DLGLNASVRYPASFDWRDQ---GMVSPVKN 133 Query: 251 QESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYA 310 Q SCGS ++F+S G +E++++I +S Q++V C P A GC GG+ A Sbjct: 134 QGSCGSSWAFSSTGAIESQMKIANGAGYDSSVSEQQLVDCVPNALGCSGGWMNDAFTYVA 193 Query: 311 QDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMA 370 Q+ G+ E +PY D C N + S Y Y+ G +E ++ + GP+A Sbjct: 194 QNGGIDSEGAYPYEMADGNCHYDPNQVAARLSGYVYLSG----PDENMLADMVATKGPVA 249 Query: 371 VAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGS 430 VAF+ D F Y G+Y+ +P HAVL+VGYG + G DYW+VKNSWG Sbjct: 250 VAFDADDPFGSYSGGVYY-----NPTCETNKFTHAVLIVGYGNE--NGQDYWLVKNSWGD 302 Query: 431 QWGESGYFRIRRG-TDECAIESIAMAAI 457 WG GYF+I R + C I +A Sbjct: 303 GWGLDGYFKIARNANNHCGIAGVASVPT 330 >4QRX-A nrPDB Length = 363 Score = 275 bits (702), Expect = 4e-74, Method: Composition-based stats. Identities = 83/323 (25%), Positives = 143/323 (44%), Gaps = 38/323 (11%) Query: 142 MANHSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKS-WTATTYEEYEKLSIRD 200 M H+ K+Y N+ ++ Y ++ N ++ N S W + +S + Sbjct: 70 MLKHN-KIYKNID-----EKIYRFEIFKDNLKYIDETNKKNNSYWLGLN--VFADMSNDE 121 Query: 201 LIRRSGHSGRILRPKPAPITDEIQQQ-ILSLPESWDWRNVRGINFVSPVRNQESCGSCYS 259 + S +E+ +++PE DWR V+PV+NQ SCGS ++ Sbjct: 122 FKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQK---GAVTPVKNQGSCGSAWA 178 Query: 260 FASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEEN 319 F+++ +E+ I+I T N S QE++ C + GC+GG+P+ AQ +G+ N Sbjct: 179 FSAVSTIESIIKIRTGNLN--EYSEQELLDCDRRSYGCNGGYPWSALQLVAQ-YGIHYRN 235 Query: 320 CFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHD-D 378 +PY C+ +E ++ NE + + + P++V E D Sbjct: 236 TYPYEGVQRYCRSREKGPYAAKTDGVR---QVQPYNEGALLYSI-ANQPVSVVLEAAGKD 291 Query: 379 FLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYF 438 F Y GI+ + +HAV VGYG + Y +++NSWG+ WGE+GY Sbjct: 292 FQLYRGGIFVGPCGNK-------VDHAVAAVGYGPN------YILIRNSWGTGWGENGYI 338 Query: 439 RIRRGTDE----CAIESIAMAAI 457 RI+RGT C + + + + Sbjct: 339 RIKRGTGNSYGVCGLYTSSFYPV 361 >6CZS-A nrPDB Length = 335 Score = 273 bits (697), Expect = 2e-73, Method: Composition-based stats. Identities = 91/305 (29%), Positives = 145/305 (47%), Gaps = 25/305 (8%) Query: 160 QEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAP- 218 + + + ++ N + A N+ ++ + + +S ++ + L +P Sbjct: 50 EYHHRLQTFASNWRKINAHNNGNHTFKMALNQ-FSDMSFAEIKH------KYLWSEPQNC 102 Query: 219 --ITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNN 276 + P S DWR NFVSPV+NQ +CGS ++F++ G LE+ I I T Sbjct: 103 SATKSNYLRGTGPYPPSVDWRKKG--NFVSPVKNQGACGSSWTFSTTGALESAIAIATGK 160 Query: 277 SQTPILSPQEVVSCSP--YAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKE 334 + L+ Q++V C+ GC GG P + G++ E+ +PY D CK + Sbjct: 161 MLS--LAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQP 218 Query: 335 NCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSD 394 + + + + +E M + + P++ AFEV DF+ Y +GIY T Sbjct: 219 GKAIGFVKDVANITIY----DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHK 274 Query: 395 PFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAM 454 + NHAVL VGYG+ G+ YWIVKNSWG QWG +GYF I RG + C + + A Sbjct: 275 ---TPDKVNHAVLAVGYGEK--NGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACAS 329 Query: 455 AAIPI 459 IP+ Sbjct: 330 YPIPL 334 >3HWN-A nrPDB Length = 258 Score = 272 bits (695), Expect = 3e-73, Method: Composition-based stats. Identities = 80/281 (28%), Positives = 125/281 (44%), Gaps = 32/281 (11%) Query: 183 KSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGI 242 ++ T EE+ ++ + R G++ + P+ P S DWR Sbjct: 3 NAFGDMTSEEFRQV-MNGFQNRKPRKGKVFQ---EPL-------FYEAPRSVDWREK--- 48 Query: 243 NFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCS--PYAQGCDGG 300 +V+PV+NQ CGSC++F++ G LE ++ T LS Q +V CS +GC+GG Sbjct: 49 GYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGR--LISLSEQNLVDCSGPQGNEGCNGG 106 Query: 301 FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMK 360 + G+ E +PY AT+ CK + + + E + Sbjct: 107 LMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDI-----PKQEKALM 161 Query: 361 LELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDP--VT 417 + GP++VA + H+ FL Y GIY +P E +H VL+VGYG + Sbjct: 162 KAVATVGPISVAIDAGHESFLFYKEGIYF-----EPDCSSEDMDHGVLVVGYGFESTESD 216 Query: 418 GLDYWIVKNSWGSQWGESGYFRIRRG-TDECAIESIAMAAI 457 YW+VKNSWG +WG GY ++ + + C I S A Sbjct: 217 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 257 >3QT4-A nrPDB Length = 329 Score = 268 bits (685), Expect = 4e-72, Method: Composition-based stats. Identities = 94/317 (29%), Positives = 143/317 (45%), Gaps = 31/317 (9%) Query: 147 EKVYVNVAHLGGLQEKYSE---RLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIR 203 +K Y + Q + + ++ HN F K V S + + K + Sbjct: 35 KKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKG--EVTYSKAMNQFGDMSKEEFLAYVN 92 Query: 204 RSGHSGRILRPK-PAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFAS 262 R G+ +PK P + L S DWR+ N VS V++Q CGS +SF++ Sbjct: 93 R----GKAQKPKHPENLRMPYVSSKKPLAASVDWRS----NAVSEVKDQGQCGSSWSFST 144 Query: 263 LGMLEARIRILTNNSQTPILSPQEVVSCSPY--AQGCDGGFPYLIAGKYAQDFGVVEENC 320 G +E ++ + LS Q ++ CS GCDGG+ A Y D+G++ E+ Sbjct: 145 TGAVEGQLALQRGR--LTSLSEQNLIDCSSSYGNAGCDGGWMD-SAFSYIHDYGIMSESA 201 Query: 321 FPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFL 380 +PY A C+ + S YY + +E + + + GP+AVA + D+ Sbjct: 202 YPYEAQGDYCRFDSSQSVTTLSGYYDLPS----GDENSLADAVGQAGPVAVAIDATDELQ 257 Query: 381 HYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRI 440 Y G+++ + NH VL+VGYG D G DYWI+KNSWGS WGESGY+R Sbjct: 258 FYSGGLFYDQTCNQSD-----LNHGVLVVGYGSD--NGQDYWILKNSWGSGWGESGYWRQ 310 Query: 441 RRG-TDECAIESIAMAA 456 R + C I + A Sbjct: 311 VRNYGNNCGIATAASYP 327 >1S4V-A nrPDB Length = 229 Score = 266 bits (679), Expect = 2e-71, Method: Composition-based stats. Identities = 78/237 (32%), Positives = 118/237 (49%), Gaps = 21/237 (8%) Query: 229 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 ++P S DWR V+ V++Q CGSC++F+++ +E +I TN + LS QE+V Sbjct: 1 TVPASVDWRKK---GAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTN--KLVSLSEQELV 55 Query: 289 SCSP-YAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C QGC+GG Q G+ E +PY A D C + S + + Sbjct: 56 DCDTDQNQGCNGGLMDYAFEFIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHE- 114 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAV 406 N+ L+ V + P++VA + DF Y G++ + ++ +H V Sbjct: 115 ---NVPENDENALLKAVANQPVSVAIDAGGSDFQFYSEGVFTGSCGTE-------LDHGV 164 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG-TDECAIESIAM-AAIPIPK 461 +VGYG + G YW VKNSWG +WGE GY R+ RG +D+ + IAM A+ PI K Sbjct: 165 AIVGYGT-TIDGTKYWTVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYPIKK 220 >1NB3-A nrPDB Length = 220 Score = 265 bits (678), Expect = 2e-71, Method: Composition-based stats. Identities = 87/231 (37%), Positives = 124/231 (53%), Gaps = 15/231 (6%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR NFVSPV+NQ SCGSC++F++ G LE+ + I T + L+ Q++V C Sbjct: 2 PPSMDWRKKG--NFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLS--LAEQQLVDC 57 Query: 291 SP--YAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVG 348 + GC GG P + G++ E+ +PY D CK + + + + + Sbjct: 58 AQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANI- 116 Query: 349 GFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 +E M + + P++ AFEV +DFL Y GIY T + NHAVL Sbjct: 117 ---TMNDEEAMVEAVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHK---TPDKVNHAVLA 170 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459 VGYG++ G+ YWIVKNSWG QWG +GYF I RG + C + + A IP+ Sbjct: 171 VGYGEE--NGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPL 219 >7PCK-A nrPDB Length = 314 Score = 263 bits (673), Expect = 9e-71, Method: Composition-based stats. Identities = 79/322 (24%), Positives = 128/322 (39%), Gaps = 35/322 (10%) Query: 144 NHSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIR 203 H ++ V + Y HN ++ + + Sbjct: 17 THRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEV----- 71 Query: 204 RSGHSGRILRPKPAPITDEIQQQILSLPE-------SWDWRNVRGINFVSPVRNQESCGS 256 + + P++ L +PE S D+R +V+PV+NQ CGS Sbjct: 72 -----VQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKK---GYVTPVKNQGQCGS 123 Query: 257 CYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVV 316 C++F+S+G LE +++ T + LSPQ +V C GC GG+ ++ G+ Sbjct: 124 CWAFSSVGALEGQLKKKTG--KLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGID 181 Query: 317 EENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVH 376 E+ +PY + C Y + NE +K + + GP++VA + Sbjct: 182 SEDAYPYVGQEESCMYNPTGKAAKCRGYREIP----EGNEKALKRAVARVGPVSVAIDAS 237 Query: 377 -DDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGES 435 F Y G+Y+ + + NHAVL VGYG G +WI+KNSWG WG Sbjct: 238 LTSFQFYSKGVYYDESCN-----SDNLNHAVLAVGYGIQK--GNKHWIIKNSWGENWGNK 290 Query: 436 GYFRIRRGTDE-CAIESIAMAA 456 GY + R + C I ++A Sbjct: 291 GYILMARNKNNACGIANLASFP 312 >5EF4-A nrPDB Length = 385 Score = 262 bits (669), Expect = 3e-70, Method: Composition-based stats. Identities = 75/309 (24%), Positives = 124/309 (40%), Gaps = 33/309 (10%) Query: 164 SERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPA------ 217 ++ +N + N + K + E+ ++ + + +S Sbjct: 55 RFNVFKYNVRRIHESNKMDKPYKLKVN-EFADMTNLEFVNTYANSKISHFQALRGSAPGS 113 Query: 218 ----PITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRIL 273 P D I + +P+ DWR N V+ V+ Q CGSC++FA++ LE I Sbjct: 114 IDTDPNKDFIYANVTKIPDKVDWREK---NAVTDVKGQGGCGSCWAFAAVVALEGINAIR 170 Query: 274 TNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPK 333 T + S Q++V C GCDGG + G+ E +PY C Sbjct: 171 TG--KLVKFSEQQLVDCDMTNAGCDGGLMEPAFTYVIKHGGIAPEASYPYVGKRETCD-- 226 Query: 334 ENCLRYYSSEYYYVGGFYGGCN-EALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTG 391 + + + G + + V H P+A ++ Y G+Y Sbjct: 227 ----KAKIKDVLKIDGRQNVPGLDEEALRKAVAHQPVATGIQLSGHGLQFYSEGVYTGDC 282 Query: 392 LSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIES 451 ++P NH V +VGYG + G+ +W VKNSWG WGE GY ++RG + + Sbjct: 283 GTEP-------NHGVGIVGYG-ENEKGIKFWTVKNSWGPTWGEKGYIHLQRGARKEGLCG 334 Query: 452 IAM-AAIPI 459 +AM ++ PI Sbjct: 335 VAMHSSFPI 343 >3PBH-A nrPDB Length = 317 Score = 261 bits (666), Expect = 6e-70, Method: Composition-based stats. Identities = 92/319 (28%), Positives = 142/319 (44%), Gaps = 54/319 (16%) Query: 175 VKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESW 234 V +N +W A + + + L R G P P + + L LP S+ Sbjct: 15 VNYVNKRNTTWQAGHN--FYNVDMSYLKRLCG----TFLGGPKPPQRVMFTEDLKLPASF 68 Query: 235 DWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC--S 291 D R + +R+Q SCGSC++F ++ + RI I TN + +S +++++C S Sbjct: 69 DAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGS 128 Query: 292 PYAQGCDGGFP-----------YLIAGKYAQDFGVVEENCFPYT---------ATDAPC- 330 GC+GG+P + G Y G C PY+ + PC Sbjct: 129 MCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVG-----CRPYSIPPCEHHVNGSRPPCT 183 Query: 331 ------KPKENCLRYYSSEY-----YYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDF 379 K + C YS Y Y + +E + E+ K+GP+ AF V+ DF Sbjct: 184 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 243 Query: 380 LHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFR 439 L Y SG+Y H + HA+ ++G+G + G YW+V NSW + WG++G+F+ Sbjct: 244 LLYKSGVYQHVTG------EMMGGHAIRILGWGVE--NGTPYWLVANSWNTDWGDNGFFK 295 Query: 440 IRRGTDECAIESIAMAAIP 458 I RG D C IES +A IP Sbjct: 296 ILRGQDHCGIESEVVAGIP 314 >3KFQ-A nrPDB Length = 221 Score = 259 bits (661), Expect = 2e-69, Method: Composition-based stats. Identities = 77/233 (33%), Positives = 115/233 (49%), Gaps = 20/233 (8%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP+S DWR +V+PV+NQ+ CGSC++F++ G LE ++ T + LS Q +V Sbjct: 1 LPKSVDWRKK---GYVTPVKNQKQCGSCWAFSATGALEGQMFRKTG--KLVSLSEQNLVD 55 Query: 290 CS--PYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 CS QGC+GGF ++ G+ E +PY A D CK + + + V Sbjct: 56 CSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVAQDTGFTVV 115 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHAV 406 E + + GP++VA + H F Y SGIY +P + +H V Sbjct: 116 ----APGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYF-----EPDCSSKNLDHGV 166 Query: 407 LLVGYGKDPVT--GLDYWIVKNSWGSQWGESGYFRIRRGT-DECAIESIAMAA 456 L+VGYG + YW+VKNSWG +WG +GY +I + + C I + A Sbjct: 167 LVVGYGFEGANSDNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYP 219 >2C0Y-A nrPDB Length = 315 Score = 258 bits (658), Expect = 5e-69, Method: Composition-based stats. Identities = 89/330 (26%), Positives = 145/330 (43%), Gaps = 38/330 (11%) Query: 134 WACFVGKKMANHSEKVYVNVAHLGGLQ--EKYSERLYSHNHNFVKAINSVQKSWTATTYE 191 W GK+ +E+ + L+ ++ H++ +N + T E Sbjct: 15 WKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHL----GDMTSE 70 Query: 192 EYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQ 251 E +S+ +R R + K P LP+S DWR V+ V+ Q Sbjct: 71 EV--MSLMSSLRVPSQWQRNITYKSNPNRI--------LPDSVDWREK---GCVTEVKYQ 117 Query: 252 ESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSPY---AQGCDGGFPYLIAGK 308 SCG+ ++F+++G LEA++++ T + LS Q +V CS +GC+GGF Sbjct: 118 GSCGAAWAFSAVGALEAQLKLKTG--KLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQY 175 Query: 309 YAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGP 368 + G+ + +PY A D C+ S+Y + E ++K + GP Sbjct: 176 IIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPY----GREDVLKEAVANKGP 231 Query: 369 MAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNS 427 ++V + H F Y SG+Y+ + + NH VL+VGYG + G +YW+VKNS Sbjct: 232 VSVGVDARHPSFFLYRSGVYYEPSCT------QNVNHGVLVVGYG--DLNGKEYWLVKNS 283 Query: 428 WGSQWGESGYFRIRRGT-DECAIESIAMAA 456 WG +GE GY R+ R + C I S Sbjct: 284 WGHNFGEEGYIRMARNKGNHCGIASFPSYP 313 >3P5W-A nrPDB Length = 220 Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats. Identities = 79/234 (33%), Positives = 116/234 (49%), Gaps = 24/234 (10%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP+ DWR+ V +++Q CGSC++F+++ +E +I T + LS QE+V Sbjct: 1 LPDYVDWRSS---GAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGD--LISLSEQELVD 55 Query: 290 C--SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C + +GCDGGF + G+ E +PYTA + C +Y S + Y Sbjct: 56 CGRTQNTRGCDGGFMTDGFQFIINNGGINTEANYPYTAEEGQCNLDLQQEKYVSIDTYEN 115 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAV 406 + N V + P++VA E +F HY SGI+ + +HAV Sbjct: 116 VPY----NNEWALQTAVAYQPVSVALEAAGYNFQHYSSGIFTGPCGTA-------VDHAV 164 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR---GTDECAIESIAMAAI 457 +VGYG + G+DYWIVKNSWG+ WGE GY RI+R G +C I A + Sbjct: 165 TIVGYGTEG--GIDYWIVKNSWGTTWGEEGYMRIQRNVGGVGQCGIAKKASYPV 216 >3OF9-A nrPDB Length = 221 Score = 256 bits (654), Expect = 2e-68, Method: Composition-based stats. Identities = 74/235 (31%), Positives = 109/235 (46%), Gaps = 21/235 (8%) Query: 229 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 P S DWR +V+PV+NQ CGSC++F++ G LE ++ T LS Q +V Sbjct: 1 EAPRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGR--LISLSEQNLV 55 Query: 289 SCS--PYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYY 346 CS +GC+GG + G+ E +PY AT+ CK + + Sbjct: 56 DCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVD 115 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHA 405 + E + + GP++VA + H+ FL Y GIY +P E +H Sbjct: 116 I-----PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYF-----EPDCSSEDMDHG 165 Query: 406 VLLVGYGKDPV--TGLDYWIVKNSWGSQWGESGYFRIRRG-TDECAIESIAMAAI 457 VL+VGYG + YW+VKNSWG +WG GY ++ + + C I S A Sbjct: 166 VLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 220 >1CQD-A nrPDB Length = 221 Score = 254 bits (648), Expect = 7e-68, Method: Composition-based stats. Identities = 77/238 (32%), Positives = 111/238 (46%), Gaps = 26/238 (10%) Query: 229 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 LP+S DWR V PV+NQ CGSC++F+++ +E +I+T + LS Q++V Sbjct: 2 DLPDSIDWREN---GAVVPVKNQGGCGSCWAFSTVAAVEGINQIVTGD--LISLSEQQLV 56 Query: 289 SCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVG 348 C+ GC GG+ + G+ E +PY D C N Y V Sbjct: 57 DCTTANHGCRGGWMNPAFQFIVNNGGINSEETYPYRGQDGICNSTVNAPVVSIDSYENVP 116 Query: 349 GFYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAVL 407 NE ++ + V + P++V + DF Y SGI+ + NHA+ Sbjct: 117 SH----NEQSLQ-KAVANQPVSVTMDAAGRDFQLYRSGIFTGSCNIS-------ANHALT 164 Query: 408 LVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT----DECAIESIAMAAIPIPK 461 +VGYG + D+WIVKNSWG WGESGY R R +C I A+ P+ K Sbjct: 165 VVGYGTE--NDKDFWIVKNSWGKNWGESGYIRAERNIENPDGKCGITR--FASYPVKK 218 >2FO5-A nrPDB Length = 262 Score = 251 bits (641), Expect = 5e-67, Method: Composition-based stats. Identities = 66/237 (27%), Positives = 98/237 (41%), Gaps = 20/237 (8%) Query: 227 ILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQE 286 + LP S DWR V+ V++Q CGSC++F+++ +E I T + LS QE Sbjct: 1 VSDLPPSVDWRQK---GAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGS--LVSLSEQE 55 Query: 287 VVSCSPY-AQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYY 345 ++ C GC GG + G++ E +PY A C + Sbjct: 56 LIDCDTADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVV-VH 114 Query: 346 YVGGFYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNH 404 G N V + P++VA E F+ Y G++ ++ +H Sbjct: 115 IDGHQDVPANSEEDLARAVANQPVSVAVEASGKAFMFYSEGVFTGECGTE-------LDH 167 Query: 405 AVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT----DECAIESIAMAAI 457 V +VGYG G YW VKNSWG WGE GY R+ + + C I A + Sbjct: 168 GVAVVGYGV-AEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYPV 223 >3BCN-A nrPDB Length = 209 Score = 250 bits (639), Expect = 8e-67, Method: Composition-based stats. Identities = 76/231 (32%), Positives = 106/231 (45%), Gaps = 28/231 (12%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE DWR V P++NQ CGSC++F+++ +E+ +I T N LS Q++V Sbjct: 1 LPEHVDWRAK---GAVIPLKNQGKCGSCWAFSTVTTVESINQIRTGN--LISLSEQQLVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 CS GC GG+ + G+ E +PY A PC+ + +R + Sbjct: 56 CSKKNHGCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPCRAAKKVVRIDGCKGV---- 111 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 CNE +K V P VA + F HY GI+ + NH V++ Sbjct: 112 --PQCNENALK-NAVASQPSVVAIDASSKQFQHYKGGIFTGPCGTK-------LNHGVVI 161 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR--GTDECAIESIAMAAI 457 VGYG DYWIV+NSWG WGE GY R++R G C I + Sbjct: 162 VGYG------KDYWIVRNSWGRHWGEQGYTRMKRVGGCGLCGIARLPFYPT 206 >5JA7-A nrPDB Length = 223 Score = 250 bits (638), Expect = 1e-66, Method: Composition-based stats. Identities = 70/228 (30%), Positives = 108/228 (47%), Gaps = 18/228 (7%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P+S D+R +V+PV+NQ CGS ++F+S+G LE +++ T + LSPQ +V C Sbjct: 10 PDSVDYRKK---GYVTPVKNQGQCGSSWAFSSVGALEGQLKKKTG--KLLNLSPQNLVDC 64 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGF 350 GC GG+ ++ G+ E+ +PY + C Y + Sbjct: 65 VSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIP-- 122 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVH-DDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLV 409 NE +K + + GP++VA + F Y G+Y+ + + NHAVL V Sbjct: 123 --EGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCN-----SDNLNHAVLAV 175 Query: 410 GYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE-CAIESIAMAA 456 GYG G +WI+KNSWG WG GY + R + C I ++A Sbjct: 176 GYGIQK--GNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFP 221 >2PNS-A nrPDB Length = 208 Score = 249 bits (637), Expect = 1e-66, Method: Composition-based stats. Identities = 78/231 (33%), Positives = 108/231 (46%), Gaps = 28/231 (12%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE DWR V+PV+NQ CGSC++F+++ +E+ +I T N LS Q++V Sbjct: 1 LPEQIDWRKK---GAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGN--LISLSEQQLVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C+ GC GG + G+ E +PY A PC+ + +R Y V Sbjct: 56 CNKKNHGCKGGAFVYAYQYIIDNGGIDTEANYPYKAVQGPCRAAKKVVR--IDGYKGVPH 113 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 CNE +K + V P VA + F HY SGI+ + NH V++ Sbjct: 114 ----CNENALK-KAVASQPSVVAIDASSKQFQHYKSGIFSGPCGTK-------LNHGVVI 161 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR--GTDECAIESIAMAAI 457 VGY DYWIV+NSWG WGE GY R++R G C I + Sbjct: 162 VGYW------KDYWIVRNSWGRYWGEQGYIRMKRVGGCGLCGIARLPYYPT 206 >4HWY-A nrPDB Length = 340 Score = 249 bits (637), Expect = 1e-66, Method: Composition-based stats. Identities = 91/315 (28%), Positives = 134/315 (42%), Gaps = 44/315 (13%) Query: 174 FVKAINSVQKS-WTATTYEEYEKLSIRDLIRRSG----HSGRILRPKPAPITDEIQQQIL 228 FV +N + + W A + +++R+ R +G ++ + PK +E + Sbjct: 36 FVDRVNRLNRGIWKAKYDGVMQNITLREAKRLNGVIKKNNNASILPKRRFTEEEARAP-- 93 Query: 229 SLPESWD----WRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSP 284 LP S+D W N + + +Q +CGSC++ A+ + R + I + Sbjct: 94 -LPSSFDSAEAWPNCPT---IPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHISAG 149 Query: 285 QEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATD-----------APCKP- 332 + CS GC+GG P A Y G+V + C PY PC Sbjct: 150 DLLACCSDCGDGCNGGDPDR-AWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQF 208 Query: 333 ---KENCLRYYSSEYYYVGGF-----YGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHS 384 C V + Y E EL GP VAF+V++DF+ Y+S Sbjct: 209 NFDTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDVYEDFIAYNS 268 Query: 385 GIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 G+YHH L HAV LVG+G G+ YW + NSW ++WG GYF IRRG+ Sbjct: 269 GVYHHVSGQ------YLGGHAVRLVGWGTS--NGVPYWKIANSWNTEWGMDGYFLIRRGS 320 Query: 445 DECAIESIAMAAIPI 459 EC IE A IP+ Sbjct: 321 SECGIEDGGSAGIPL 335 >4P6E-A nrPDB Length = 230 Score = 249 bits (637), Expect = 1e-66, Method: Composition-based stats. Identities = 75/232 (32%), Positives = 116/232 (50%), Gaps = 22/232 (9%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP+S DWR V+ V+ Q SCG+C++F+++G LEA++++ T + LS Q +V Sbjct: 7 LPDSVDWREK---GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTG--KLVSLSAQNLVD 61 Query: 290 CSPY---AQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYY 346 CS +GC+GGF + G+ + +PY A D C+ S+Y Sbjct: 62 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTE 121 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHA 405 + E ++K + GP++V + H F Y SG+Y+ + + NH Sbjct: 122 LPY----GREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT------QNVNHG 171 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT-DECAIESIAMAA 456 VL+VGYG + G +YW+VKNSWG +GE GY R+ R + C I S Sbjct: 172 VLVVGYG--DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYP 221 >2O6X-A nrPDB Length = 310 Score = 248 bits (634), Expect = 3e-66, Method: Composition-based stats. Identities = 90/317 (28%), Positives = 143/317 (45%), Gaps = 40/317 (12%) Query: 155 HLGGLQEKYSERLYSHNHNFVKAINSVQ-----------KSWTATTYEEYEKLSIRDLIR 203 G +++ ++ N ++ N +T T+EE++ + ++ R Sbjct: 15 EYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSR 74 Query: 204 RSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASL 263 S + + ++P+ DWR +V+ V++Q +CGS ++F++ Sbjct: 75 ASDILSHGV---------PYEANNRAVPDKIDWRES---GYVTEVKDQGNCGSGWAFSTT 122 Query: 264 GMLEARIRILTNNSQTPILSPQEVVSCSP--YAQGCDGGFPYLIAGKYAQDFGVVEENCF 321 G +E + + N + S Q++V CS GC GG +Y + FG+ E+ + Sbjct: 123 GTMEGQY--MKNERTSISFSEQQLVDCSRPWGNNGCGGGLMENAY-QYLKQFGLETESSY 179 Query: 322 PYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLH 381 PYTA + C+ + + +Y V +E +K + GP AVA +V DF+ Sbjct: 180 PYTAVEGQCRYNKQLGVAKVTGFYTV----HSGSEVELKNLVGAEGPAAVAVDVESDFMM 235 Query: 382 YHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIR 441 Y SGIY S NHAVL VGYG G DYWIVKNSWG WGE GY R+ Sbjct: 236 YRSGIYQSQTCS-----PLRVNHAVLAVGYGTQG--GTDYWIVKNSWGLSWGERGYIRMV 288 Query: 442 RGT-DECAIESIAMAAI 457 R + C I S+A + Sbjct: 289 RNRGNMCGIASLASLPM 305 >6BKI-A nrPDB Length = 215 Score = 248 bits (633), Expect = 3e-66, Method: Composition-based stats. Identities = 73/229 (31%), Positives = 110/229 (48%), Gaps = 18/229 (7%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 +P+S D+R +V+PV+NQ CGSC++F+S G LE +++ T + LSPQ +V Sbjct: 1 VPDSIDYRKK---GYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTG--KLLALSPQNLVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C GC GG+ Q+ G+ E+ +PY D C Y + Sbjct: 56 CVTENYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNAAAKAAKCRGYREIP- 114 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVH-DDFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 NE +K + + GP++V+ + F Y G+Y+ D + NHAVL+ Sbjct: 115 ---VGNEKALKRAVARVGPISVSIDASLASFQFYSRGVYY-----DENCDRDNVNHAVLV 166 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE-CAIESIAMAA 456 VGYG G +WI+KNSWG WG GY + R + C I ++A Sbjct: 167 VGYGTQK--GSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMASFP 213 >4BS5-A nrPDB Length = 225 Score = 248 bits (632), Expect = 5e-66, Method: Composition-based stats. Identities = 71/234 (30%), Positives = 110/234 (47%), Gaps = 23/234 (9%) Query: 229 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 +LP++ DWR V+ V+ Q SCG+C++F+++G LE ++++ T + LS Q +V Sbjct: 7 TLPDTVDWREK---GCVTEVKYQGSCGACWAFSAVGALEGQLKLKTG--KLISLSAQNLV 61 Query: 289 SCSPY----AQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEY 344 CS +GC GG+ + G+ + +PY A D C S Y Sbjct: 62 DCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRY 121 Query: 345 YYVGGFYGGCNEALMKLELVKHGPMAVAFEVH-DDFLHYHSGIYHHTGLSDPFNPFELTN 403 + +E +K + GP++V + F Y SG+Y + N Sbjct: 122 IQLP----FGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTG------NVN 171 Query: 404 HAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR-GTDECAIESIAMAA 456 H VL+VGYG + G DYW+VKNSWG +G+ GY R+ R + C I S Sbjct: 172 HGVLVVGYGT--LDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYP 223 >1AEC-A nrPDB Length = 218 Score = 248 bits (632), Expect = 5e-66, Method: Composition-based stats. Identities = 72/234 (30%), Positives = 111/234 (47%), Gaps = 24/234 (10%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP DWR+ V +++Q CG C++F+++ +E +I+T LS QE++ Sbjct: 1 LPSYVDWRS---AGAVVDIKSQGECGGCWAFSAIATVEGINKIVTG--VLISLSEQELID 55 Query: 290 C--SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C + +GC+GG+ + G+ E +PYTA D C +Y + + Y Sbjct: 56 CGRTQNTRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKYVTIDTYEN 115 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAV 406 + N V + P++VA + D F Y SGI+ + +HAV Sbjct: 116 VPY----NNEWALQTAVTYQPVSVALDAAGDAFKQYSSGIFTGPCGTA-------IDHAV 164 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR---GTDECAIESIAMAAI 457 +VGYG + G+DYWIVKNSW + WGE GY RI R G C I ++ + Sbjct: 165 TIVGYGTEG--GIDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 216 >1IWD-A nrPDB Length = 215 Score = 248 bits (632), Expect = 6e-66, Method: Composition-based stats. Identities = 71/234 (30%), Positives = 105/234 (44%), Gaps = 27/234 (11%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP DWR+ V+ ++NQ+ CGSC++F+++ +E+ +I T Q LS QE+V Sbjct: 1 LPSFVDWRSK---GAVNSIKNQKQCGSCWAFSAVAAVESINKIRTG--QLISLSEQELVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C + GC+GG+ + G+ + +PY+A CKP Y + G Sbjct: 56 CDTASHGCNGGWMNNAFQYIITNGGIDTQQNYPYSAVQGSCKP-------YRLRVVSING 108 Query: 350 FY-GGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAVL 407 F N V P++V E F HY SGI+ + NH V+ Sbjct: 109 FQRVTRNNESALQSAVASQPVSVTVEAAGAPFQHYSSGIFTGPCGTAQ-------NHGVV 161 Query: 408 LVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG----TDECAIESIAMAAI 457 +VGYG +G +YWIV+NSWG WG GY + R C I + Sbjct: 162 IVGYGTQ--SGKNYWIVRNSWGQNWGNQGYIWMERNVASSAGLCGIAQLPSYPT 213 >5JT8-A nrPDB Length = 333 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 89/319 (27%), Positives = 144/319 (45%), Gaps = 32/319 (10%) Query: 148 KVYVNVAHLGGLQEKYSERL-YSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSG 206 KVY N + + E+L + HN + + ++ + +E+ SG Sbjct: 37 KVYRNAEEEARREHHFKEQLKWVEEHNGIDGVEYAINEYSDMSEQEFS-------FHLSG 89 Query: 207 HSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGML 266 K + + SLP+++DWR + + +R Q SCGSC++FA+ G+ Sbjct: 90 GGLNFTYMKMEAAKEPLINTYGSLPQNFDWRQKARL---TRIRQQGSCGSCWAFAAAGVA 146 Query: 267 EARIRILTNNSQTPILSPQEVVSCSPYAQ-------GCDGGFPYLIAGKYAQDFGVVEEN 319 E+ I Q+ LS QE+V C+ GC G+ A KY G+VEE Sbjct: 147 ESLYSIQ--KQQSIELSEQELVDCTYNRYDPSYQCNGCGSGY-STEAFKYMIRTGLVEER 203 Query: 320 CFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDD- 378 +PY C P RY+ S Y + Y +E +M + +HGP+ + ++ Sbjct: 204 NYPYNMRTQWCDPDVEGQRYHVSGYQQL--RYHSSDEDVM-YTIQQHGPVVIYMHGSNNY 260 Query: 379 FLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYF 438 F + +G+ +D + +HAV+LVG+G V G+DYWI++NSWG+ WG GY Sbjct: 261 FRNLGNGVLRGVAYNDAYT-----DHAVILVGWGT--VQGVDYWIIRNSWGTGWGNGGYG 313 Query: 439 RIRRGTDECAIESIAMAAI 457 + RG + I + A Sbjct: 314 YVERGHNSLGINNYVTYAT 332 >1O0E-A nrPDB Length = 208 Score = 245 bits (625), Expect = 4e-65, Method: Composition-based stats. Identities = 77/233 (33%), Positives = 107/233 (45%), Gaps = 32/233 (13%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE DWR V+PV+NQ SCGSC++F+++ +E+ +I T N LS QE+V Sbjct: 1 LPEQIDWRKK---GAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGN--LISLSEQELVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C GC GG + G+ + +PY A PC+ +S+ + G Sbjct: 56 CDKKNHGCLGGAFVFAYQYIINNGGIDTQANYPYKAVQGPCQA--------ASKVVSIDG 107 Query: 350 FYGG--CNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAV 406 + G CNE +K + V P VA + F Y SGI+ + NH V Sbjct: 108 YNGVPFCNEXALK-QAVAVQPSTVAIDASSAQFQQYSSGIFSGPCGTK-------LNHGV 159 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR--GTDECAIESIAMAAI 457 +VGY + YWIV+NSWG WGE GY R+ R G C I + Sbjct: 160 TIVGYQAN------YWIVRNSWGRYWGEKGYIRMLRVGGCGLCGIARLPYYPT 206 >4YYR-A nrPDB Length = 222 Score = 244 bits (623), Expect = 5e-65, Method: Composition-based stats. Identities = 71/239 (29%), Positives = 117/239 (48%), Gaps = 27/239 (11%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE+ DWR V+P+RNQ CGSC++F+ + ++E +I+T+ + P LS Q++V Sbjct: 1 LPETVDWRIQ---GAVNPIRNQGRCGSCWAFSVVVVVEGITKIVTD--ELPSLSEQQLVD 55 Query: 290 C--SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C S GC GG+ ++ G+ ++ +PYTA C + + Y Sbjct: 56 CATSYKNLGCSGGWMTKAYDYIIKNGGITSQSNYPYTAKKGECNKDLASQIVATIDSYE- 114 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAV 406 + N V + P++V E F Y SG++ + + +HAV Sbjct: 115 ---HVPRNNENALKNAVANQPVSVTIEAGGRAFELYKSGVFVGSCGTK-------LDHAV 164 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG----TDECAIESIAMAAIPIPK 461 + +GYG + +DYW+V+NSWG+ WGE GY +++R T +C I + P+ K Sbjct: 165 VAIGYGSE--NDVDYWLVRNSWGTNWGERGYIKLQRNVAEPTGKCGIA--MQSTYPVKK 219 >4I04-A nrPDB Length = 323 Score = 242 bits (617), Expect = 3e-64, Method: Composition-based stats. Identities = 81/305 (26%), Positives = 129/305 (42%), Gaps = 39/305 (12%) Query: 182 QKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNV-R 240 W A + L + + LR P D + +P S+D R Sbjct: 25 NAGWRAEKSNRFHSLDDARIQMGARREEPDLRRTRRPTVDHNDWNV-EIPSSFDSRKKWP 83 Query: 241 GINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCS-PYAQGCDG 299 ++ +R+Q CGS ++F ++ + R I + Q LS +++SC GC+G Sbjct: 84 RCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQNVELSAVDLLSCCESCGLGCEG 143 Query: 300 GF----------PYLIAGKYAQDFGVVEENCFPYTATD-----APC--------KPKENC 336 G ++ G ++ E FP PC + K+ C Sbjct: 144 GILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPCGSKIYKTPRCKQTC 203 Query: 337 LRYYSSEYYY-----VGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTG 391 + Y + Y + +E ++ E++K+GP+ F V++DFL+Y SGIY H Sbjct: 204 QKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVYEDFLNYKSGIYKHIT 263 Query: 392 LSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIES 451 L HA+ ++G+G + YW++ NSW WGE+GYFRI RG DEC+IES Sbjct: 264 G------ETLGGHAIRIIGWGVE--NKAPYWLIANSWNEDWGENGYFRIVRGRDECSIES 315 Query: 452 IAMAA 456 A Sbjct: 316 EVTAG 320 >2VHS-A nrPDB Length = 217 Score = 241 bits (616), Expect = 4e-64, Method: Composition-based stats. Identities = 72/231 (31%), Positives = 104/231 (45%), Gaps = 20/231 (8%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR +V+PV+NQ CG+ Y+F++ G LE ++ T LS Q +V C Sbjct: 2 PRSVDWREK---GYVTPVKNQGQCGASYAFSATGALEGQMFRKTGR--LISLSEQNLVDC 56 Query: 291 S--PYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVG 348 S +GC+GG + G+ E +PY AT+ CK + + Sbjct: 57 SGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDVGFVDI- 115 Query: 349 GFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHAVL 407 E + + GP++VA + H+ FL Y GIY NHA+L Sbjct: 116 ----PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYF-----SSDCSSSSLNHAML 166 Query: 408 LVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG-TDECAIESIAMAAI 457 +VGYG YW+VKNSWG +WG GY ++ + + C I S A Sbjct: 167 VVGYGF-ISNNQKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 216 >4YYW-A nrPDB Length = 220 Score = 241 bits (614), Expect = 7e-64, Method: Composition-based stats. Identities = 69/235 (29%), Positives = 115/235 (48%), Gaps = 25/235 (10%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE+ DWR+ V P+R+Q CGSC+ F+ ++E ++I+T+ P LS QE++ Sbjct: 1 LPETVDWRSK---GAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDT--LPSLSEQELLD 55 Query: 290 C--SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C S GC GG+ +D G+ E+ +PYTA C ++ + Y Sbjct: 56 CAPSYKDLGCKGGWMDKAYDYIIKDRGITSESDYPYTARKGACDSRKATEVVATISSYE- 114 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHDDF-LHYHSGIYHHTGLSDPFNPFELTNHAV 406 + + V + P++VA + Y SG++ + +HAV Sbjct: 115 ---DVPADNEDALKKAVANQPVSVAIDASSAAVKEYSSGVFVGSCGVA-------NDHAV 164 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIESIAMAAI 457 ++VGYG + +G++YW+V+NSWG++WGE GY ++ R T C I + + Sbjct: 165 VVVGYGTE--SGVNYWLVRNSWGTKWGEEGYMKLERDTAHPAGKCGIAMESTYPV 217 >2ACT-A nrPDB Length = 220 Score = 240 bits (613), Expect = 9e-64, Method: Composition-based stats. Identities = 72/234 (30%), Positives = 112/234 (47%), Gaps = 24/234 (10%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LP DWR+ V +++Q CG C++F+++ +E +I + + LS QE++ Sbjct: 1 LPSYVDWRS---AGAVVDIKSQGECGGCWAFSAIATVEGINKITSGS--LISLSEQELID 55 Query: 290 C--SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C + +GCDGG+ D G+ E +PYTA D C +Y + + Y Sbjct: 56 CGRTQNTRGCDGGYITDGFQFIINDGGINTEENYPYTAQDGDCDVALQDQKYVTIDTYEN 115 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAV 406 + N V + P++VA + D F Y SGI+ + +HA+ Sbjct: 116 VPY----NNEWALQTAVTYQPVSVALDAAGDAFKQYASGIFTGPCGTA-------VDHAI 164 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRR---GTDECAIESIAMAAI 457 ++VGYG + G+DYWIVKNSW + WGE GY RI R G C I ++ + Sbjct: 165 VIVGYGTEG--GVDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 216 >1MIR-A nrPDB Length = 322 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 88/315 (27%), Positives = 142/315 (45%), Gaps = 46/315 (14%) Query: 175 VKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESW 234 + IN +W A + + I L + G + P + ++LPES+ Sbjct: 14 INYINKQNTTWQA--GRNFYNVDISYLKKLCG----TVLGGPKLPERVGFSEDINLPESF 67 Query: 235 DWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCS-- 291 D R ++ +R+Q SCGS ++F ++ + RI I TN +S +++++C Sbjct: 68 DAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGI 127 Query: 292 PYAQGCDGGFPYLIAGKYAQDFGVVEENCF-------PYT---------ATDAPC----- 330 GC+GG+P A + G+V + PYT PC Sbjct: 128 QCGDGCNGGYPSG-AWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPCTGEGD 186 Query: 331 --KPKENCLRYYSSEY-----YYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYH 383 K + C YS+ Y Y + +E + E+ K+GP+ AF V DFL Y Sbjct: 187 TPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYK 246 Query: 384 SGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG 443 SG+Y H + HA+ ++G+G + G+ YW+V NSW + WG++G+F+I RG Sbjct: 247 SGVYKHEAGD------VMGGHAIRILGWGIE--NGVPYWLVANSWNADWGDNGFFKILRG 298 Query: 444 TDECAIESIAMAAIP 458 + C IES +A IP Sbjct: 299 ENHCGIESEIVAGIP 313 >3CBK-A nrPDB Length = 266 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 82/270 (30%), Positives = 125/270 (46%), Gaps = 48/270 (17%) Query: 224 QQQILSLPESWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPIL 282 + L LP S+D R + +R+Q SCGS ++F ++ + RI I TN + + Sbjct: 1 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEV 60 Query: 283 SPQEVVSC--SPYAQGCDGGFP-----------YLIAGKYAQDFGVVEENCFPYT----- 324 S +++++C S GC+GG+P + G Y G C PY+ Sbjct: 61 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVG-----CRPYSIPPCE 115 Query: 325 ----ATDAPC-------KPKENCLRYYSSEY-----YYVGGFYGGCNEALMKLELVKHGP 368 PC K + C YS Y Y + +E + E+ K+GP Sbjct: 116 AHVNGARPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP 175 Query: 369 MAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSW 428 + AF V+ DFL Y SG+Y H + HA+ ++G+G + G YW+V NSW Sbjct: 176 VEGAFSVYSDFLLYKSGVYQHVTG------EMMGGHAIRILGWGVE--NGTPYWLVANSW 227 Query: 429 GSQWGESGYFRIRRGTDECAIESIAMAAIP 458 + WG++G+F+I RG D C IES +A IP Sbjct: 228 NTDWGDNGFFKILRGQDHCGIESEVVAGIP 257 >4I05-A nrPDB Length = 285 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 79/275 (28%), Positives = 124/275 (45%), Gaps = 39/275 (14%) Query: 212 LRPKPAPITDEIQQQILSLPESWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARI 270 LR P D + +P S+D R ++ +R+Q CGSC++F ++ + R Sbjct: 17 LRRTRRPTVDHNDWNV-EIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRS 75 Query: 271 RILTNNSQTPILSPQEVVSCS-PYAQGCDGGF----------PYLIAGKYAQDFGVVEEN 319 I + Q LS +++SC GC+GG ++ G ++ E Sbjct: 76 CIQSGGKQNVELSAVDLLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPY 135 Query: 320 CFPYTATD-----APC--------KPKENCLRYYSSEYYY-----VGGFYGGCNEALMKL 361 FP PC + K+ C + Y + Y + +E ++ Sbjct: 136 PFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQK 195 Query: 362 ELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDY 421 E++K+GP+ F V++DFL+Y SGIY H L HA+ ++G+G + Y Sbjct: 196 EIMKYGPVEAGFTVYEDFLNYKSGIYKHITG------ETLGGHAIRIIGWGVE--NKAPY 247 Query: 422 WIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAA 456 W++ NSW WGE+GYFRI RG DEC+IES A Sbjct: 248 WLIANSWNEDWGENGYFRIVRGRDECSIESEVTAG 282 >2BDZ-A nrPDB Length = 214 Score = 237 bits (605), Expect = 7e-63, Method: Composition-based stats. Identities = 73/232 (31%), Positives = 111/232 (47%), Gaps = 28/232 (12%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 PES DWR V+PV+NQ CGSC++F+++ +E +I+T Q LS QE++ C Sbjct: 2 PESIDWREK---GAVTPVKNQNPCGSCWAFSTVATIEGINKIITG--QLISLSEQELLDC 56 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGF 350 + GCDGG+ +Y D GV E +PY C+ K+ + Y G Sbjct: 57 ERRSHGCDGGYQTTSL-QYVVDNGVHTEREYPYEKKQGRCRAKDK----KGPKVYITGYK 111 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAVLLV 409 Y N+ + ++ + + P++V + F Y GIY ++ +HAV V Sbjct: 112 YVPANDEISLIQAIANQPVSVVTDSRGRGFQFYKGGIYEGPCGTNT-------DHAVTAV 164 Query: 410 GYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIESIAMAAI 457 GYG Y ++KNSWG WGE GY RI+R + C + + + I Sbjct: 165 GYG------KTYLLLKNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFPI 210 >1CPJ-A nrPDB Length = 260 Score = 236 bits (603), Expect = 1e-62, Method: Composition-based stats. Identities = 81/266 (30%), Positives = 129/266 (48%), Gaps = 40/266 (15%) Query: 224 QQQILSLPESWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPIL 282 + ++LPES+D R ++ +R+Q SCGSC++F ++ + RI I TN + Sbjct: 1 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV 60 Query: 283 SPQEVVSCS--PYAQGCDGGFPYLIAGKYAQDFGVVEENCF-------PYT--------- 324 S +++++C GC+GG+P A + G+V + PYT Sbjct: 61 SAEDLLTCCGIQCGDGCNGGYPSG-AWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVN 119 Query: 325 ATDAPC-------KPKENCLRYYSSEY-----YYVGGFYGGCNEALMKLELVKHGPMAVA 372 PC K + C YS+ Y Y + +E + E+ K+GP+ A Sbjct: 120 GARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGA 179 Query: 373 FEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQW 432 F V DFL Y SG+Y H + HA+ ++G+G + G+ YW+V NSW + W Sbjct: 180 FTVFSDFLTYKSGVYKHEAGD------VMGGHAIRILGWGIE--NGVPYWLVANSWNADW 231 Query: 433 GESGYFRIRRGTDECAIESIAMAAIP 458 G++G+F+I RG + C IES +A IP Sbjct: 232 GDNGFFKILRGENHCGIESEIVAGIP 257 >2B1M-A nrPDB Length = 246 Score = 236 bits (601), Expect = 2e-62, Method: Composition-based stats. Identities = 77/233 (33%), Positives = 105/233 (45%), Gaps = 18/233 (7%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 PESWDW ++ V+ Q CGS ++F++ G +EA I T N LS QE++ C Sbjct: 3 PESWDWSKK---GVITKVKFQGQCGSGWAFSATGAIEAAHAIATGN--LVSLSEQELIDC 57 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEY--YYVG 348 ++GC G+ Y + G+ E +PY A D CK E + Y + Sbjct: 58 VDESEGCYNGWHYQSFEWVVKHGGIASEADYPYKARDGKCKANEIQDKVTIDNYGVQILS 117 Query: 349 GFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 V P++V+ + DF Y GIY S P+ NH VL+ Sbjct: 118 NESTESEAESSLQSFVLEQPISVSIDAK-DFHFYSGGIYDGGNCSSPYG----INHFVLI 172 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIESIAMAAI 457 VGYG + G+DYWI KNSWG WG GY RI+R T C + A I Sbjct: 173 VGYGSE--DGVDYWIAKNSWGEDWGIDGYIRIQRNTGNLLGVCGMNYFASYPI 223 >6MIS-A nrPDB Length = 215 Score = 235 bits (600), Expect = 3e-62, Method: Composition-based stats. Identities = 72/232 (31%), Positives = 110/232 (47%), Gaps = 23/232 (9%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 +P+S DWR+ V+ V+NQ CGSC++FAS+ +E+ +I N LS Q+V+ Sbjct: 1 VPQSIDWRDS---GAVTSVKNQGRCGSCWAFASIATVESIYKIKRGN--LVSLSEQQVLD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C+ + GC GG+ + GV +PY A CK Y + Y YV Sbjct: 56 CA-VSYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQR 114 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLV 409 N + V + P+A A + +F HY G++ + NHA++++ Sbjct: 115 -----NNERNMMYAVSNQPIAAALDASGNFQHYKRGVFTGPCGTR-------LNHAIVII 162 Query: 410 GYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT----DECAIESIAMAAI 457 GYG+D +G +WIV+NSWG+ WGE GY R+ R C I + Sbjct: 163 GYGQDS-SGKKFWIVRNSWGAGWGEGGYIRLARDVSSSFGLCGIAMDPLYPT 213 >3F75-A nrPDB Length = 224 Score = 234 bits (596), Expect = 8e-62, Method: Composition-based stats. Identities = 74/235 (31%), Positives = 109/235 (46%), Gaps = 21/235 (8%) Query: 229 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 LP DWR+ V+PV++Q CGSC++F++ G LE T + LS QE++ Sbjct: 6 ELPAGVDWRSR---GCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTG--KLVSLSEQELM 60 Query: 289 SCSPY--AQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYY 346 CS Q C GG G+ E+ +PY A D C+ + + Sbjct: 61 DCSRAEGNQSCSGGEMNDAFQYVLDSGGICSEDAYPYLARDEECRAQSCEKVVKILGFKD 120 Query: 347 VGGFYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHA 405 V +EA MK L K P+++A E F YH G++ + +D +H Sbjct: 121 VPRR----SEAAMKAALAK-SPVSIAIEADQMPFQFYHEGVFDASCGTD-------LDHG 168 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAM-AAIPI 459 VLLVGYG D + D+WI+KNSWG+ WG GY + E + + A+ P+ Sbjct: 169 VLLVGYGTDKESKKDFWIMKNSWGTGWGRDGYMYMAMHKGEEGQCGLLLDASFPV 223 >6EXO-A nrPDB Length = 215 Score = 233 bits (595), Expect = 1e-61, Method: Composition-based stats. Identities = 67/232 (28%), Positives = 109/232 (46%), Gaps = 25/232 (10%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P + DWR V+PV++Q CGSC++F+++G +E + ++ N LS Q +VSC Sbjct: 2 PAAVDWREK---GAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGN--PLVSLSEQMLVSC 56 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVV--EENCFPYT---ATDAPCKPKENCLRYYSSEYY 345 GC GG G E +PY C+ + + +++ Sbjct: 57 DTIDFGCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHV 116 Query: 346 YVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHA 405 + +E + L ++GP+A+A + F+ Y+ GI E +H Sbjct: 117 DL-----PQDEDAIAAYLAENGPLAIAVDATS-FMDYNGGILTS-------CTSEQLDHG 163 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAI 457 VLLVGY + + YWI+KNSW + WGE GY RI +GT++C + +A+ Sbjct: 164 VLLVGY--NDASNPPYWIIKNSWSNMWGEDGYIRIEKGTNQCLMNQAVSSAV 213 >2CIO-A nrPDB Length = 212 Score = 233 bits (595), Expect = 1e-61, Method: Composition-based stats. Identities = 72/233 (30%), Positives = 113/233 (48%), Gaps = 28/233 (12%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 +PE DWR V+PV+NQ SCGSC++F+++ +E I+I T N S QE++ Sbjct: 1 IPEYVDWRQK---GAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLN--QYSEQELLD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C + GC+GG+P+ AQ +G+ N +PY C+ +E ++ Sbjct: 56 CDRRSYGCNGGYPWSALQLVAQ-YGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVR--- 111 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 NE + + + P++V E DF Y GI+ + +HAV Sbjct: 112 QVQPYNEGALLYSI-ANQPVSVVLEAAGKDFQLYRGGIFVGPCGNK-------VDHAVAA 163 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIESIAMAAI 457 VGYG + Y ++KNSWG+ WGE+GY RI+RGT C + + + + Sbjct: 164 VGYGPN------YILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPV 210 >1YAL-A nrPDB Length = 218 Score = 233 bits (593), Expect = 2e-61, Method: Composition-based stats. Identities = 70/233 (30%), Positives = 108/233 (46%), Gaps = 26/233 (11%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P+S DWR V+PV+NQ +CGSC++F+++ +E +I+T N LS QE+V C Sbjct: 2 PQSIDWRAK---GAVTPVKNQGACGSCWAFSTIATVEGINKIVTGN--LLELSEQELVDC 56 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKP-KENCLRYYSSEYYYVGG 349 ++ GC GG+ +Y + GV +PY A C+ + + + Y V Sbjct: 57 DKHSYGCKGGYQTTSL-QYVANNGVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVPS 115 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 N L + + P++V E F Y SG++ + +HAV Sbjct: 116 -----NCETSFLGALANQPLSVLVEAGGKPFQLYKSGVFDGPCGTK-------LDHAVTA 163 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIESIAMAAI 457 VGYG G +Y I+KNSWG WGE GY R++R + C + + Sbjct: 164 VGYGTS--DGKNYIIIKNSWGPNWGEKGYMRLKRQSGNSQGTCGVYKSSYYPF 214 >4CDF-B nrPDB Length = 166 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 145/164 (88%), Positives = 152/164 (92%) Query: 228 LSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEV 287 L LP SWDWRNV GINFVSPVRNQ SCGSCYSFAS+GMLEARIRILTNNSQTPILSPQEV Sbjct: 1 LHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEV 60 Query: 288 VSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 VSCS YAQGC+GGFPYLIAGKYAQDFG+VEE CFPYT TD+PCK KE+C RYYSSEY+YV Sbjct: 61 VSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYV 120 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTG 391 GGFYGGCNEALMKLELV HGPMAVAFEV+DDFLHY GIYHHTG Sbjct: 121 GGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTG 164 >1PPO-A nrPDB Length = 216 Score = 232 bits (591), Expect = 3e-61, Method: Composition-based stats. Identities = 71/233 (30%), Positives = 105/233 (45%), Gaps = 24/233 (10%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE+ DWR V+PVR+Q SCGSC++F+++ +E +I T + LS QE+V Sbjct: 1 LPENVDWRKK---GAVTPVRHQGSCGSCWAFSAVATVEGINKIRTG--KLVELSEQELVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C + GC GG+P A +Y G+ + +PY A C+ K+ + G Sbjct: 56 CERRSHGCKGGYP-PYALEYVAKNGIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGV---G 111 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 NE + L + P++V E F Y GI+ + +HAV Sbjct: 112 RVQPNNEGNL-LNAIAKQPVSVVVESKGRPFQLYKGGIFEGPCGTK-------VDHAVTA 163 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIESIAMAAI 457 V G G Y ++KNSWG+ WGE GY RI+R C + + Sbjct: 164 V--GYGKSGGKGYILIKNSWGTAWGEKGYIRIKRAPGNSPGVCGLYKSSYYPT 214 >5A24-A nrPDB Length = 222 Score = 230 bits (587), Expect = 8e-61, Method: Composition-based stats. Identities = 72/235 (30%), Positives = 107/235 (45%), Gaps = 21/235 (8%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 +P + DWR V+PV+NQ+ CG C++F+++ +E +I T LS +++V Sbjct: 1 VPAAVDWR---TAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGT--LTSLSEEQIVD 55 Query: 290 CSPYA--QGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C +GC+GG P + G+ E+ +PYTA P Y Sbjct: 56 CDTNGNDKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGGS--PGTCSASSYQPAASIT 113 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAV 406 G N + P++VA + D F Y SGIY ++ +HAV Sbjct: 114 GYQDVPANNEQALQQAAATQPISVAIDASDPSFQSYSSGIYSGPCNTN-------LDHAV 166 Query: 407 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIESIAMAAI 457 +VGYG DP +G YWIVKNSWG+ WG+ GY ++ G + C I A Sbjct: 167 TVVGYGTDPNSGNSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGVCGIAMQASYPT 221 >5OGQ-A nrPDB Length = 254 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 75/259 (28%), Positives = 120/259 (46%), Gaps = 38/259 (14%) Query: 228 LSLPESWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQE 286 + +P S+D R ++ +R+Q CGSC++F ++ + R I + Q LS + Sbjct: 1 VEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVD 60 Query: 287 VVSCS-PYAQGCDGGF----------PYLIAGKYAQDFGVVEENCFPYTATD-----APC 330 ++SC GC+GG ++ G ++ E FP PC Sbjct: 61 LLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPC 120 Query: 331 --------KPKENCLRYYSSEYYY-----VGGFYGGCNEALMKLELVKHGPMAVAFEVHD 377 + K+ C + Y + Y + +E ++ E++K+GP+ F V++ Sbjct: 121 GSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVYE 180 Query: 378 DFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGY 437 DFL+Y SGIY H L HA+ ++G+G + YW++ NSW WGE+GY Sbjct: 181 DFLNYKSGIYKHITG------ETLGGHAIRIIGWGVE--NKAPYWLIANSWNEDWGENGY 232 Query: 438 FRIRRGTDECAIESIAMAA 456 FRI RG DEC+IES A Sbjct: 233 FRIVRGRDECSIESEVTAG 251 >4YYQ-A nrPDB Length = 217 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 68/233 (29%), Positives = 114/233 (48%), Gaps = 23/233 (9%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPE+ DWR+ V+P+RNQ CGSC++F+++ +E+ +I+T + + Sbjct: 1 LPETVDWRSK---GAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLLDCA 57 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 S GC GG+ Q+ G+ ++ +PYT C+ + Y YV Sbjct: 58 QSYKNLGCQGGWVNKAFEYIIQNRGITSQSNYPYTGHKGQCRTGLASI-ATIDSYQYVPS 116 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 NE +K V + P++VA E F Y SG++ + +HAV+L Sbjct: 117 ----NNENALK-NAVANQPVSVAVEAAGRAFQLYKSGVFTGSCGVA-------IDHAVVL 164 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG----TDECAIESIAMAAI 457 +GYGK G+DYW+++NSWG+ WGE GY +++R +C + + + + Sbjct: 165 IGYGK--YNGVDYWLLRNSWGTNWGEQGYMKLQRNVAQSAGKCGVARLCLYPV 215 >3U8E-A nrPDB Length = 222 Score = 227 bits (578), Expect = 9e-60, Method: Composition-based stats. Identities = 68/233 (29%), Positives = 100/233 (42%), Gaps = 22/233 (9%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR V+ V++Q +CG C++F + G +E I T +S Q++V C Sbjct: 2 PASIDWRKK---GAVTSVKDQGACGMCWAFGATGAIEGIDAITTGR--LISVSEQQIVDC 56 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGF 350 GG + G+ + +PYT D C + + G+ Sbjct: 57 DTXXXXXXGGDADDAFRWVITNGGIASDANYPYTGVDGTCDLNKPIAA-------RIDGY 109 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHS-GIYHHTGLSDPFNPFELTNHAVLL 408 N + L+ V P++V F Y GI+ + SD +H VL+ Sbjct: 110 TNVPNSSSALLDAVAKQPVSVNIYTSSTSFQLYTGPGIFAGSSCSD---DPATVDHTVLI 166 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIESIAMAAI 457 VGYG + DYWIVKNSWG++WG GY IRR T+ CAI++ Sbjct: 167 VGYGSNGTN-ADYWIVKNSWGTEWGIDGYILIRRNTNRPDGVCAIDAWGSYPT 218 >1GEC-E nrPDB Length = 216 Score = 224 bits (572), Expect = 5e-59, Method: Composition-based stats. Identities = 73/233 (31%), Positives = 108/233 (46%), Gaps = 24/233 (10%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 LPES DWR V+PV++Q C SC++F+++ +E +I T N LS QE+V Sbjct: 1 LPESVDWRAK---GAVTPVKHQGYCESCWAFSTVATVEGINKIKTGN--LVELSEQELVD 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C + GC+ G+ AQ+ G+ +PY A C+ + + G Sbjct: 56 CDLQSYGCNRGYQSTSLQYVAQN-GIHLRAKYPYIAKQQTCRANQVGGPKVKTNGV---G 111 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 NE + L + H P++V E DF +Y GI+ + + +HAV Sbjct: 112 RVQSNNEGSL-LNAIAHQPVSVVVESAGRDFQNYKGGIFEGSCGTK-------VDHAVTA 163 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIESIAMAAI 457 VGYGK G ++KNSWG WGE+GY RIRR + C + + I Sbjct: 164 VGYGKSGGKGY--ILIKNSWGPGWGENGYIRIRRASGNSPGVCGVYRSSYYPI 214 >4PI3-A nrPDB Length = 216 Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats. Identities = 68/232 (29%), Positives = 110/232 (47%), Gaps = 25/232 (10%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P + DWR V+ V++Q CGSC++F+++G +E + + LS Q +VSC Sbjct: 3 PAAVDWR---ARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLA--GHPLTNLSEQMLVSC 57 Query: 291 SPYAQGCDGGFPYLIAGKYAQ--DFGVVEENCFPY---TATDAPCKPKENCLRYYSSEYY 345 GC GG Q + V E+ +PY PC + + + + Sbjct: 58 DKTDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHV 117 Query: 346 YVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHA 405 + +EA + L +GP+AVA + ++ Y G+ E +H Sbjct: 118 EL-----PQDEAQIAAWLAVNGPVAVAVDASS-WMTYTGGVMTS-------CVSEQLDHG 164 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAI 457 VLLVGY + + YWI+KNSW +QWGE GY RI +G+++C ++ A +A+ Sbjct: 165 VLLVGY--NDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAV 214 >3BPM-A nrPDB Length = 243 Score = 218 bits (555), Expect = 4e-57, Method: Composition-based stats. Identities = 72/238 (30%), Positives = 108/238 (45%), Gaps = 32/238 (13%) Query: 233 SWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSP 292 ++DWR G V+PV++Q CGSC++F+S+G +E++ I + S QE+V CS Sbjct: 23 AYDWRLHGG---VTPVKDQALCGSCWAFSSVGSVESQYAIRKKA--LFLFSEQELVDCSV 77 Query: 293 YAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTAT-DAPCKPKENCLRYYSSEYYYVGGFY 351 GC GG+ G+ ++ +PY + C K RY Y + Sbjct: 78 KNNGCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIKSYVSIP--- 134 Query: 352 GGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGY 411 + K L GP++++ DDF Y G Y + P NHAV+LVGY Sbjct: 135 ----DDKFKEALRYLGPISISIAASDDFAFYRGGFYDGECGAAP-------NHAVILVGY 183 Query: 412 GKDPVTGLD--------YWIVKNSWGSQWGESGYFRIRRGTD----ECAIESIAMAAI 457 G + D Y+I+KNSWGS WGE GY + + C+I + A + Sbjct: 184 GMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPL 241 >5FPW-A nrPDB Length = 321 Score = 217 bits (552), Expect = 9e-57, Method: Composition-based stats. Identities = 82/311 (26%), Positives = 123/311 (39%), Gaps = 38/311 (12%) Query: 173 NFVKAINSVQKS-WTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLP 231 FV IN + W A + + ++ + R +G + P P+ +Q LP Sbjct: 18 TFVDRINQLNGGMWKAVYNGKMQNITFAEAKRLTGAWIQKTSSLP-PVRFTEEQLRTELP 76 Query: 232 ESWD----WRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEV 287 ES+D W N I + +Q +C + ++ ++ ++ R + Q I + + Sbjct: 77 ESFDSAEKWPNCPTIR---EIADQSACRASWAVSTASVISDRYCTVGGVQQLRISAAHLL 133 Query: 288 VSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPY----------TATDAPC------- 330 C GC GGFP A +Y ++G+ C PY PC Sbjct: 134 SCCKQCGGGCKGGFPGF-AWRYYVEYGIASSYCQPYPFPHCEHRGAQGNKTPCSKYNFDT 192 Query: 331 -KPKENCLRYYSS--EYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIY 387 K + C +Y + E K EL +GP F V+ D Y SG+Y Sbjct: 193 PKCQATCTDKSIPLVKYRGSATYLLLHGEEDYKRELYFNGPFVAVFYVYTDLFAYKSGVY 252 Query: 388 HHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDEC 447 H L AV +VG+GK + G YW V N+W + WG GY I RG +EC Sbjct: 253 RHVDGD------FLGGTAVKVVGWGK--LNGTPYWKVANTWDTDWGMDGYLLILRGNNEC 304 Query: 448 AIESIAMAAIP 458 IE + A P Sbjct: 305 NIEHLGFAGTP 315 >3BPF-A nrPDB Length = 241 Score = 216 bits (551), Expect = 1e-56, Method: Composition-based stats. Identities = 72/241 (29%), Positives = 112/241 (46%), Gaps = 34/241 (14%) Query: 232 ESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCS 291 ++DWR G V+PV++Q++CGSC++F+S+G +E++ I N + LS QE+V CS Sbjct: 20 AAYDWRLHSG---VTPVKDQKNCGSCWAFSSIGSVESQYAIRKN--KLITLSEQELVDCS 74 Query: 292 PYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAP-CKPKENCLRYYSSEYYYVGGF 350 GC+GG + G+ + +PY + C +Y Y V Sbjct: 75 FKNYGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVP-- 132 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVG 410 + +K L GP++++ V DDF Y GI+ + NHAV+LVG Sbjct: 133 -----DNKLKEALRFLGPISISVAVSDDFAFYKEGIFDGECG-------DQLNHAVMLVG 180 Query: 411 YG--------KDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTD----ECAIESIAMAAIP 458 +G Y+I+KNSWG QWGE G+ I +C + + A IP Sbjct: 181 FGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAF--IP 238 Query: 459 I 459 + Sbjct: 239 L 239 >3IOQ-A nrPDB Length = 213 Score = 216 bits (549), Expect = 2e-56, Method: Composition-based stats. Identities = 68/233 (29%), Positives = 104/233 (44%), Gaps = 28/233 (12%) Query: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVS 289 +P S DWR V+PVRNQ CGSC++F+S+ +E +I+T + Sbjct: 1 IPTSIDWRQK---GAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELL--D 55 Query: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGG 349 C + GC GGFP L A +Y + G+ +PY C+ + ++ G Sbjct: 56 CERRSYGCRGGFP-LYALQYVANSGIHLRQYYPYEGVQRQCRASQAKGPKVKTDGV---G 111 Query: 350 FYGGCNEALMKLELVKHGPMAVAFEVHDD-FLHYHSGIYHHTGLSDPFNPFELTNHAVLL 408 NE + + P+++ E F +Y GI+ + +HAV Sbjct: 112 RVPRNNEQALIQRI-AIQPVSIVVEAKGRAFQNYRGGIFAGPCGTS-------IDHAVAA 163 Query: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE----CAIESIAMAAI 457 VGYG DY ++KNSWG+ WGE GY RI+RG+ C + S ++ Sbjct: 164 VGYGN------DYILIKNSWGTGWGEGGYIRIKRGSGNPQGACGVLSDSVFPT 210 >1M6D-A nrPDB Length = 214 Score = 213 bits (542), Expect = 2e-55, Method: Composition-based stats. Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 16/227 (7%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P WDWR+ V+ V++Q CGSC++F+ G +E + + N LS QE++ C Sbjct: 2 PPEWDWRSK---GAVTKVKDQGMCGSCWAFSVTGNVEGQWFL--NQGTLLSLSEQELLDC 56 Query: 291 SPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGF 350 + C GG P G+ E+ + Y C+ + Y + + Sbjct: 57 DKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCQFSAEKAKVYIQDSVEL--- 113 Query: 351 YGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVG 410 NE + L K GP++VA Y GI + P L +HAVLLVG Sbjct: 114 --SQNEQKLAAWLAKRGPISVAINAFG-MQFYRHGI---SRPLRPLCSPWLIDHAVLLVG 167 Query: 411 YGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAI 457 YG+ + + +W +KNSWG+ WGE GY+ + RG+ C + ++A +A+ Sbjct: 168 YGQR--SDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAV 212 >2DCB-A nrPDB Length = 256 Score = 211 bits (537), Expect = 5e-55, Method: Composition-based stats. Identities = 77/264 (29%), Positives = 120/264 (45%), Gaps = 48/264 (18%) Query: 230 LPESWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 LPES+D R + +R+Q SCGSC++F ++ + RI I +N +S ++++ Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 289 SCSPYAQGC-------DGGFPY------LIAGKYAQDFGVVEENCFPYT---------AT 326 +C G G + + + G Y G C PY+ + Sbjct: 61 TCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVG-----CRPYSIPPCEHHVNGS 115 Query: 327 DAPC-------KPKENCLRYYSSEYYY-----VGGFYGGCNEALMKLELVKHGPMAVAFE 374 PC K + C YS Y + NE + E+ K+GP+ AF Sbjct: 116 RPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFS 175 Query: 375 VHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGE 434 V+ DFL Y SG+Y H + HA+ ++G+G + G YW+V NSW + WG+ Sbjct: 176 VYSDFLLYKSGVYQHVSG------EIMGGHAIRILGWGVE--NGTPYWLVGNSWNTDWGD 227 Query: 435 SGYFRIRRGTDECAIESIAMAAIP 458 +G+F+I RG D C IES +A +P Sbjct: 228 NGFFKILRGQDHCGIESEIVAGMP 251 >5VPK-A nrPDB Length = 223 Score = 208 bits (530), Expect = 4e-54, Method: Composition-based stats. Identities = 75/235 (31%), Positives = 111/235 (47%), Gaps = 22/235 (9%) Query: 226 QILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQ 285 +++P D R++R V+P+R Q CGSC++F+ + E+ N + LS Q Sbjct: 7 NSVNVPSELDLRSLRT---VTPIRMQGGCGSCWAFSGVAATESAYLAYRNT--SLDLSEQ 61 Query: 286 EVVSCSPYAQGCDGG-FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEY 344 E+V C+ GC G P I +Y Q GVVEE +PY A + C+ + N Y S Y Sbjct: 62 ELVDCASQ-HGCHGDTIPRGI--EYIQQNGVVEERSYPYVAREQQCR-RPNSQHYGISNY 117 Query: 345 YYVGGFYGGCNEALMKLELVKHGPMAVAFEVHD--DFLHYHSGIYHHTGLSDPFNPFELT 402 + Y + + + H +AV + D F HY + N ++ Sbjct: 118 CQI---YPPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDG-----RTIIQHDNGYQPN 169 Query: 403 NHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAI 457 HAV +VGYG G+DYWIV+NSW + WG+SGY + G + IE I Sbjct: 170 YHAVNIVGYG--STQGVDYWIVRNSWDTTWGDSGYGYFQAGNNLMMIEQYPYVVI 222 >1XKG-A nrPDB Length = 312 Score = 207 bits (526), Expect = 9e-54, Method: Composition-based stats. Identities = 79/292 (27%), Positives = 124/292 (42%), Gaps = 28/292 (9%) Query: 173 NFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSL-- 230 NF++++ VQ + A + LS+ + R S + S+ Sbjct: 31 NFLESVKYVQSNGGAINH--LSDLSLDEFKNRFLMSAEAFEHLKTQFDLNAETNACSING 88 Query: 231 --PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 P D R +R V+P+R Q CGS ++F+ + E+ + Q+ L+ QE+V Sbjct: 89 NAPAEIDLRQMRT---VTPIRMQGGCGSAWAFSGVAATESAYLAYRD--QSLDLAEQELV 143 Query: 289 SCSPYAQGCDGG-FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C+ GC G P I +Y Q GVV+E+ + Y A + C+ + N R+ S Y + Sbjct: 144 DCASQ-HGCHGDTIPRGI--EYIQHNGVVQESYYRYVAREQSCR-RPNAQRFGISNYCQI 199 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHD--DFLHYHSGIYHHTGLSDPFNPFELTNHA 405 Y + + H +AV + D F HY + N ++ HA Sbjct: 200 ---YPPNANKIREALAQTHSAIAVIIGIKDLDAFRHYDG-----RTIIQRDNGYQPNYHA 251 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAI 457 V +VGY G+DYWIV+NSW + WG++GY D IE I Sbjct: 252 VNIVGY--SNAQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIEEYPYVVI 301 >1DEU-A nrPDB Length = 277 Score = 204 bits (518), Expect = 8e-53, Method: Composition-based stats. Identities = 78/249 (31%), Positives = 108/249 (43%), Gaps = 28/249 (11%) Query: 209 GRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQ---ESCGSCYSFASLGM 265 GR P+P LP+SWDWRNV G+N+ S RNQ + CGSC++ AS Sbjct: 20 GRTTYPRP-----HEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSA 74 Query: 266 LEARIRILTNNSQ-TPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYT 324 + RI I + + +LS Q V+ C C+GG L YA G+ +E C Y Sbjct: 75 MADRINIKRKGAWPSTLLSVQNVIDCGNAG-SCEGG-NDLSVWDYAHQHGIPDETCNNYQ 132 Query: 325 ATDAPCKPKENCL---------RYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEV 375 A D C C + + VG + M E+ +GP++ Sbjct: 133 AKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMA 192 Query: 376 HDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGES 435 + +Y GIY + NH V + G+G G +YWIV+NSWG WGE Sbjct: 193 TERLANYTGGIYAE------YQDTTYINHVVSVAGWGIS--DGTEYWIVRNSWGEPWGER 244 Query: 436 GYFRIRRGT 444 G+ RI T Sbjct: 245 GWLRIVTST 253 >1ICF-A nrPDB Length = 175 Score = 204 bits (518), Expect = 9e-53, Method: Composition-based stats. Identities = 58/189 (30%), Positives = 87/189 (46%), Gaps = 18/189 (9%) Query: 231 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 290 P S DWR +V+PV+NQ CGSC++F++ G LE ++ T LS Q +V C Sbjct: 2 PRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGR--LISLSEQNLVDC 56 Query: 291 S--PYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVG 348 S +GC+GG + G+ E +PY AT+ CK + + + Sbjct: 57 SGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI- 115 Query: 349 GFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHAVL 407 E + + GP++VA + H+ FL Y GIY +P E +H VL Sbjct: 116 ----PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYF-----EPDCSSEDMDHGVL 166 Query: 408 LVGYGKDPV 416 +VGYG + Sbjct: 167 VVGYGFEST 175 >5VCN-A nrPDB Length = 222 Score = 201 bits (510), Expect = 6e-52, Method: Composition-based stats. Identities = 71/232 (30%), Positives = 106/232 (45%), Gaps = 22/232 (9%) Query: 229 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 + P D R +R V+P+R Q CGSC++F+ + E+ N Q+ L+ QE+V Sbjct: 9 NAPAEIDLRQMRT---VTPIRMQGGCGSCWAFSGVAATESAYLAYRN--QSLDLAEQELV 63 Query: 289 SCSPYAQGCDGG-FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYV 347 C+ GC G P I +Y Q GVV+E+ + Y A + C+ + N R+ S Y + Sbjct: 64 DCASQ-HGCHGDTIPRGI--EYIQHNGVVQESYYRYVAREQSCR-RPNAQRFGISNYCQI 119 Query: 348 GGFYGGCNEALMKLELVKHGPMAVAFEVHD--DFLHYHSGIYHHTGLSDPFNPFELTNHA 405 Y + + H +AV + D F HY + N ++ HA Sbjct: 120 ---YPPNANKIREALAQTHSAIAVIIGIKDLDAFRHYDG-----RTIIQRDNGYQPNYHA 171 Query: 406 VLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAI 457 V +VGY G+DYWIV+NSW + WG++GY D IE I Sbjct: 172 VNIVGY--SNAQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIEEYPYVVI 221 >1EF7-A nrPDB Length = 242 Score = 197 bits (500), Expect = 1e-50, Method: Composition-based stats. Identities = 74/228 (32%), Positives = 103/228 (45%), Gaps = 23/228 (10%) Query: 230 LPESWDWRNVRGINFVSPVRNQ---ESCGSCYSFASLGMLEARIRILTNNSQ-TPILSPQ 285 LP+SWDWRNV G+N+ S RNQ + CGSC++ AS + RI I + + +LS Q Sbjct: 1 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 60 Query: 286 EVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCL-------- 337 V+ C C+GG L YA G+ +E C Y A D C C Sbjct: 61 NVIDCGNAG-SCEGG-NDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKEC 118 Query: 338 -RYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPF 396 + + VG + M E+ +GP++ + +Y GIY + Sbjct: 119 HAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAE------Y 172 Query: 397 NPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT 444 NH V + G+G G +YWIV+NSWG WGE G+ RI T Sbjct: 173 QDTTYINHVVSVAGWGIS--DGTEYWIVRNSWGEPWGERGWLRIVTST 218 >1CSB-B nrPDB Length = 205 Score = 170 bits (430), Expect = 1e-42, Method: Composition-based stats. Identities = 64/215 (29%), Positives = 98/215 (45%), Gaps = 47/215 (21%) Query: 278 QTPILSPQEVVSC--SPYAQGCDGGFP-----------YLIAGKYAQDFGVVEENCFPYT 324 + +S +++++C S GC+GG+P + G Y G C PY+ Sbjct: 1 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVG-----CRPYS 55 Query: 325 ---------ATDAPC-------KPKENCLRYYSSEY-----YYVGGFYGGCNEALMKLEL 363 + PC K + C YS Y Y + +E + E+ Sbjct: 56 IPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEI 115 Query: 364 VKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWI 423 K+GP+ AF V+ DFL Y SG+Y H + HA+ ++G+G + G YW+ Sbjct: 116 YKNGPVEGAFSVYSDFLLYKSGVYQHVTG------EMMGGHAIRILGWGVE--NGTPYWL 167 Query: 424 VKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIP 458 V NSW + WG++G+F+I RG D C IES +A IP Sbjct: 168 VANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 202 >1SP4-B nrPDB Length = 205 Score = 147 bits (370), Expect = 1e-35, Method: Composition-based stats. Identities = 55/177 (31%), Positives = 80/177 (45%), Gaps = 34/177 (19%) Query: 303 YLIAGKYAQDFGVVEENCFPYT---------ATDAPC-------KPKENCLRYYSSEYYY 346 + G Y G C PY+ + PC K + C YS Y Sbjct: 40 LVSGGLYNSHVG-----CRPYSIPPCEHHVNGSRPPCTGEGDTPKCNKTCEPGYSPSYKE 94 Query: 347 -----VGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFEL 401 + NE + E+ K+GP+ AF V+ DFL Y SG+Y H + Sbjct: 95 DKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSG------EIM 148 Query: 402 TNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIP 458 HA+ ++G+G + G YW+V NSW + WG++G+F+I RG D C IES +A +P Sbjct: 149 GGHAIRILGWGVE--NGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGMP 203 >5I4H-A nrPDB Length = 106 Score = 138 bits (348), Expect = 4e-33, Method: Composition-based stats. Identities = 36/109 (33%), Positives = 52/109 (47%), Gaps = 7/109 (6%) Query: 229 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 288 P S DWR +V+PV+NQ CGS ++F++ G LE ++ T LS Q +V Sbjct: 1 EAPRSVDWREK---GYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGR--LISLSEQNLV 55 Query: 289 SCS--PYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKEN 335 CS +GC+GG + G+ E +PY AT+ CK Sbjct: 56 DCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPK 104 >5I4H-B nrPDB Length = 112 Score = 122 bits (306), Expect = 3e-28, Method: Composition-based stats. Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 9/109 (8%) Query: 353 GCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGY 411 E + + GP++VA + H+ FL Y GIY +P E +H VL+VGY Sbjct: 8 PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYF-----EPDCSSEDMDHGVLVVGY 62 Query: 412 GKDPV--TGLDYWIVKNSWGSQWGESGYFRIRRG-TDECAIESIAMAAI 457 G + YW+VKNSWG +WG GY ++ + + C I S A Sbjct: 63 GFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 111 >4OEM-B nrPDB Length = 70 Score = 118 bits (295), Expect = 6e-27, Method: Composition-based stats. Identities = 59/69 (85%), Positives = 64/69 (92%) Query: 394 DPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIA 453 DPFNPFELTNHAVLLVGYG D +G+DYWIVKNSWG+ WGE+GYFRIRRGTDECAIESIA Sbjct: 1 DPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIA 60 Query: 454 MAAIPIPKL 462 +AA PIPKL Sbjct: 61 VAATPIPKL 69 >3CH2-X nrPDB Length = 265 Score = 97.5 bits (241), Expect = 1e-20, Method: Composition-based stats. Identities = 54/247 (21%), Positives = 89/247 (36%), Gaps = 40/247 (16%) Query: 247 PVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQG--CDGGFPYL 304 V +Q +C + + FAS LE + +S V +C CD G + Sbjct: 23 QVEDQGNCDTSWIFASKYHLETIRCMKGYEP--TKISALYVANCYKGEHKDRCDEGSSPM 80 Query: 305 IAGKYAQDFG-VVEENCFPY--TATDAPC-------------------KPKENCLRYYSS 342 + +D+G + E+ +PY C K + N L Sbjct: 81 EFLQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPNSLDGKGY 140 Query: 343 EYYYVGGFYGGCNE--ALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFE 400 Y F+ + ++K E++ G + + + G + Sbjct: 141 TAYESERFHDNMDAFVKIIKTEVMNKGSVIAYIKAENV-----MGYEFSGKKVQNLCGDD 195 Query: 401 LTNHAVLLVGYGK---DPVTGLDYWIVKNSWGSQWGESGYFRIRR-GTDECA---IESIA 453 +HAV +VGYG YWIV+NSWG WG+ GYF++ G C I S+ Sbjct: 196 TADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHCHFNFIHSVV 255 Query: 454 MAAIPIP 460 + + +P Sbjct: 256 IFNVDLP 262 >4CI7-A nrPDB Length = 470 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 54/294 (18%), Positives = 99/294 (33%), Gaps = 39/294 (13%) Query: 170 HNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILS 229 +H + + + + S + Y E + D + ++G I P T + S Sbjct: 4 GSHKTLDGVETAEYSESYLQY--LEDVKNGDTAK---YNGVIPFPHEMEGTTLRNKGRSS 58 Query: 230 LPESWDWR---NVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQE 286 LP ++ N + +P +NQ S + +SF+ + LEA +++ T LS + Sbjct: 59 LPSAYKSSVAYNPMDLGLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYG--TYDLSEEH 116 Query: 287 VVSCSPYAQGCDGGF--PYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEY 344 + +A G G+ + G + P D P K Sbjct: 117 L---RWWATGGKYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSN 173 Query: 345 YYVGGFY--------GGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPF 396 ++ +K ++++G V + HY + + Sbjct: 174 MDTAPTQFNVTDVVRLNKDKETVKNAIMQYG------SVTSGYAHYSTYFNKDETAYNCT 227 Query: 397 NPFELTNHAVLLVGYGKD----------PVTGLDYWIVKNSWGSQWGESGYFRI 440 N NHAV +VG+ + W+VK+SWG G+F I Sbjct: 228 NKRAPLNHAVAIVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWI 281 >4D59-A nrPDB Length = 406 Score = 68.2 bits (165), Expect = 7e-12, Method: Composition-based stats. Identities = 41/219 (18%), Positives = 73/219 (33%), Gaps = 31/219 (14%) Query: 242 INFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGF 301 + +P +NQ S + +SF+ + LEA +++ T LS + + +A G G+ Sbjct: 10 LGLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYG--TYDLSEEHL---RWWATGGKYGW 64 Query: 302 --PYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFY-------- 351 + G + P D P K Sbjct: 65 NLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVR 124 Query: 352 GGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGY 411 ++ +K ++++G V + HY + + N NHAV +VG+ Sbjct: 125 LNKDKETVKNAIMQYG------SVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGW 178 Query: 412 GKD----------PVTGLDYWIVKNSWGSQWGESGYFRI 440 + W+VK+SWG G+F I Sbjct: 179 DDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWI 217 >3OIS-A nrPDB Length = 291 Score = 61.3 bits (147), Expect = 9e-10, Method: Composition-based stats. Identities = 52/248 (20%), Positives = 84/248 (33%), Gaps = 44/248 (17%) Query: 216 PAPITDEIQQQILSLPESWDWRNVRGINFVSP---VRNQESCGSCYSFASLGMLEARIRI 272 + I +LP D ++P V +Q GSC + A ++ RI Sbjct: 43 RDFSYTPEKSVIAALPPKVD---------LTPPFQVYDQGRIGSCTANALAAAIQ-FERI 92 Query: 273 LTNNSQTPILSPQEVVSCSPYAQG---CDGGFPYLIAGKYAQDFGVVEENCFPY------ 323 S I S + +G D G K GV E +PY Sbjct: 93 HDKQSPEFIPSRLFIYYNERKIEGHVNYDSGAMIRDGIKVLHKLGVCPEKEWPYGDTPAD 152 Query: 324 -----------TATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVA 372 + + ++ Y +EY V + +K L P Sbjct: 153 PRTEEFPPGAPASKKPSDQCYKDAQNYKITEYSRVA-----QDIDHLKACLAVGSPFVFG 207 Query: 373 FEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQW 432 F V++ ++ +S + N HAVL VGY + + ++ ++NSWG+ Sbjct: 208 FSVYNSWVGNNSLPVRIPLPTK--NDTLEGGHAVLCVGYDDE----IRHFRIRNSWGNNV 261 Query: 433 GESGYFRI 440 GE GYF + Sbjct: 262 GEDGYFWM 269 >4K7C-A nrPDB Length = 446 Score = 41.6 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 387 YHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDY-WIVKNSWGSQWGESGYF 438 + T L HA++L G D V G W V+NSWG + GE GYF Sbjct: 347 FTMTKAERLDYGESLMTHAMVLTG--VDLVDGKPTKWKVENSWGEKVGEKGYF 397 Score = 28.5 bits (62), Expect = 6.6, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 17/30 (56%), Gaps = 4/30 (13%) Query: 248 VRNQESCGSCYSFASLGML----EARIRIL 273 V NQ+ G C+ FA+L + +A+ +I Sbjct: 61 VSNQKQSGRCWMFAALNTMRHGIQAQFKIK 90 >5WDK-A nrPDB Length = 401 Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 396 FNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQ 431 N +H + + G KD G +Y++VKNSWG+ Sbjct: 328 DNYETTDDHGMQIYGIAKDQ-EGNEYYMVKNSWGTN 362 Score = 33.9 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 243 NFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSP 284 N ++ V+NQ G+C+ ++S LE+ + + LS Sbjct: 38 NPITSVKNQNRAGTCWCYSSYSFLESELLRMGKG--EYDLSE 77 >2QGM-A nrPDB Length = 445 Score = 35.1 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 29/72 (40%), Gaps = 2/72 (2%) Query: 258 YSFASLGMLEARIRILTNNSQ--TPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGV 315 ++ A+ +E +L N L Q + + +AQ GG + A G+ Sbjct: 255 WAKATASAIEKFTTMLLPNDYPSIIKLHEQYLADHAMWAQETFGGKTMVWAHNIHIAKGI 314 Query: 316 VEENCFPYTATD 327 ++E +PY A Sbjct: 315 IDEKLYPYVAGQ 326 >3X1F-A nrPDB Length = 352 Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 21/51 (41%), Gaps = 5/51 (9%) Query: 383 HSGIYHHTGLSDPFNPFELTN-HAVLLV----GYGKDPVTGLDYWIVKNSW 428 G++ + + P H V++V GY D +Y +++N W Sbjct: 156 KPGVFMYHCGTKPVLQHIANGMHGVIIVKPKNGYPTDKEVDREYVLIQNEW 206 >3WIA-A nrPDB Length = 287 Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 21/51 (41%), Gaps = 5/51 (9%) Query: 383 HSGIYHHTGLSDPFNPFELTN-HAVLLV----GYGKDPVTGLDYWIVKNSW 428 G++ + + P H V++V GY D +Y +++N W Sbjct: 91 KPGVFMYHCGTKPVLQHIANGMHGVIIVKPKNGYPTDKEVDREYVLIQNEW 141 >2CB5-A nrPDB Length = 453 Score = 33.5 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 17/45 (37%), Gaps = 2/45 (4%) Query: 398 PFELTNHAVLLVGYGKDPVTGLDY--WIVKNSWGSQWGESGYFRI 440 L HA+ + + W V+NSWG G GY + Sbjct: 365 GESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCM 409 >1A6R-A nrPDB Length = 471 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 19/42 (45%), Gaps = 11/42 (26%) Query: 246 SPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEV 287 +PV NQ+S G + FA+ TN + +LS + Sbjct: 79 TPVTNQKSSGRAWLFAA-----------TNQLRLNVLSELNL 109 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 1/38 (2%) Query: 400 ELTNHAVLLVGYGKDPVTGLDY-WIVKNSWGSQWGESG 436 L HA+L+ G D + L + V+NSWG G+ G Sbjct: 382 SLMTHAMLITGCHVDETSKLPLRYRVENSWGKDSGKDG 419 >2Z51-A nrPDB Length = 154 Score = 29.7 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 7/15 (46%), Positives = 9/15 (60%) Query: 243 NFVSPVRNQESCGSC 257 V V+ Q +CGSC Sbjct: 34 GNVVRVKLQGACGSC 48 >1G0D-A nrPDB Length = 695 Score = 29.3 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 29/79 (36%), Gaps = 12/79 (15%) Query: 189 TYEEYEKLSIRDLIRRSGHSGRILRPKPAPITD---EIQQQILSLPESWDWRNVRGINFV 245 + Y +I ++ +G G + P TD + S+P W V Sbjct: 210 SDPVYVGRTITAMVNSNGDRGVLTGRWEEPYTDGVAPYRWT-GSVPILQQWSKAG----V 264 Query: 246 SPVRNQESCGSCYSFASLG 264 PV+ G C+ FA++ Sbjct: 265 RPVKY----GQCWVFAAVA 279 >6G90-C nrPDB Length = 231 Score = 28.9 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 19/50 (38%), Gaps = 3/50 (6%) Query: 117 YCHETMTGWVHDVLGRNWACFVGKKMANHSEKVYVNVAHLGGLQEKYSER 166 YCH +T HD L + VGK + Y N A + + R Sbjct: 8 YCHSYLT---HDTLSVRKSHLVGKNHLRITADYYRNKARDIINKHNHKRR 54 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.132 0.428 Lambda K H 0.267 0.0405 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,531,245 Number of Sequences: 36641 Number of extensions: 826736 Number of successful extensions: 2749 Number of sequences better than 10.0: 89 Number of HSP's better than 10.0 without gapping: 160 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 1943 Number of HSP's gapped (non-prelim): 192 length of query: 462 length of database: 10,336,785 effective HSP length: 100 effective length of query: 362 effective length of database: 6,672,685 effective search space: 2415511970 effective search space used: 2415511970 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 61 (28.1 bits)