BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P78417 (241 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3LFL-A nrPDB 490 e-139 3QAG-A nrPDB 337 4e-93 3WD6-A nrPDB 159 1e-39 3RBT-A nrPDB 122 1e-28 4QQ7-A nrPDB 96 1e-20 2VO4-A nrPDB 78 4e-15 4J2F-A nrPDB 75 2e-14 4CHS-A nrPDB 74 4e-14 5G5A-A nrPDB 73 1e-13 5IQY-A nrPDB 72 2e-13 4PQI-A nrPDB 71 5e-13 5J5N-A nrPDB 70 7e-13 6EP7-A nrPDB 70 9e-13 5D9W-A nrPDB 69 2e-12 4AGS-A nrPDB 67 9e-12 5ELG-A nrPDB 67 1e-11 2CZ2-A nrPDB 65 3e-11 5ECL-B nrPDB 65 3e-11 1FW1-A nrPDB 65 3e-11 1E6B-A nrPDB 63 1e-10 5LOL-A nrPDB 62 2e-10 1GWC-A nrPDB 57 7e-09 3IBH-A nrPDB 55 3e-08 4MK3-A nrPDB 55 3e-08 3UBL-A nrPDB 55 3e-08 5N9U-A nrPDB 52 2e-07 4IGJ-A nrPDB 52 3e-07 4PXO-A nrPDB 52 3e-07 6JWK-A nrPDB 52 3e-07 3M3M-A nrPDB 52 3e-07 3PR8-A nrPDB 51 4e-07 4PNG-A nrPDB 50 6e-07 4YH2-A nrPDB 48 3e-06 1OYJ-A nrPDB 48 4e-06 3R2Q-A nrPDB 47 5e-06 3NIV-A nrPDB 47 6e-06 2IL3-A nrPDB 46 2e-05 2PMT-A nrPDB 44 5e-05 3TOT-A nrPDB 44 6e-05 3VWX-A nrPDB 44 9e-05 3M8N-A nrPDB 43 1e-04 5NR1-A nrPDB 43 1e-04 2JL4-A nrPDB 42 2e-04 2FHE-A nrPDB 42 2e-04 1AW9-A nrPDB 42 2e-04 5A5K-A nrPDB 42 3e-04 3UAR-A nrPDB 41 4e-04 2PVQ-A nrPDB 41 4e-04 1F2E-A nrPDB 41 5e-04 2GDR-A nrPDB 40 8e-04 4MDC-A nrPDB 40 0.001 5F07-A nrPDB 40 0.001 4PTS-A nrPDB 39 0.001 2D2Z-A nrPDB 39 0.002 5F06-A nrPDB 37 0.006 3M1G-A nrPDB 36 0.015 4Q5F-A nrPDB 36 0.015 2R5G-A nrPDB 36 0.017 1N2A-A nrPDB 36 0.019 3C8E-A nrPDB 35 0.020 2WRT-A nrPDB 35 0.025 1AXD-A nrPDB 35 0.036 1JLV-A nrPDB 35 0.042 3GX0-A nrPDB 34 0.072 5F05-A nrPDB 33 0.083 5Y7I-A nrPDB 33 0.11 2FIC-A nrPDB 32 0.25 5F0G-A nrPDB 31 0.49 1FHE-A nrPDB 31 0.58 1XWK-A nrPDB 31 0.59 6GCB-A nrPDB 30 0.84 2KLX-A nrPDB 30 0.84 1TU7-A nrPDB 30 0.94 4K0G-A nrPDB 29 1.5 1B4P-A nrPDB 29 1.5 4TR1-A nrPDB 29 1.8 3IR4-A nrPDB 29 1.9 3GTU-B nrPDB 29 2.0 3GRX-A nrPDB 29 2.0 2DC5-A nrPDB 29 2.1 3QMX-A nrPDB 28 2.6 5FWG-A nrPDB 28 2.6 4G0L-A nrPDB 28 3.1 3NH5-A nrPDB 28 3.2 1G7O-A nrPDB 28 3.2 1PN9-A nrPDB 28 3.4 5LLW-B nrPDB 28 5.1 3FK2-A nrPDB 28 5.1 5LLY-D nrPDB 27 5.5 5IRC-A nrPDB 27 7.3 6GC9-A nrPDB 27 7.9 >3LFL-A nrPDB Length = 240 Score = 490 bits (1262), Expect = e-139, Method: Compositional matrix adjust. Identities = 240/241 (99%), Positives = 240/241 (99%), Gaps = 1/241 (0%) Query: 1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP 60 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP Sbjct: 1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP 60 Query: 61 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF 120 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF Sbjct: 61 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF 120 Query: 121 SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW 180 SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKL EVLTNKKTTFFGGNSISMIDYLIWPW Sbjct: 121 SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKL-EVLTNKKTTFFGGNSISMIDYLIWPW 179 Query: 181 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG 240 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG Sbjct: 180 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG 239 Query: 241 L 241 L Sbjct: 240 L 240 >3QAG-A nrPDB Length = 239 Score = 337 bits (863), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 156/239 (65%), Positives = 189/239 (79%), Gaps = 1/239 (0%) Query: 1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP 60 MSG++ R+LGKGS PPGPVPEG IRIYSMRFCP++ RTRLVLKAK IRHEV+NINL+NKP Sbjct: 1 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP 60 Query: 61 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF 120 EW++ K+PFG +PVLE SQ QLIYES I CEYLD+AYPG+KL P DPYE+A QKM+LELF Sbjct: 61 EWYYTKHPFGHIPVLETSQSQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF 120 Query: 121 SKVPSLVG-SFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP 179 SKVP L + ++ + LK R+EF+ LEE+L + TTFFGG SISMIDYL+WP Sbjct: 121 SKVPHLTKECLVALRSGRESTNLKAALRQEFSNLEEILEYQNTTFFGGTSISMIDYLLWP 180 Query: 180 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACD 238 WFERL+ + +CV HTP L+LW++AMK DPTVSALL + +QGFL LY QN+P A D Sbjct: 181 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVSALLMDKSIFQGFLNLYFQNNPNAFD 239 >3WD6-A nrPDB Length = 256 Score = 159 bits (401), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 92/232 (39%), Positives = 129/232 (55%), Gaps = 13/232 (5%) Query: 5 SARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFF 64 + + L KG P P G +R+Y+MR+CP+A+RT L L AK I +EV+NI+L +KPEW Sbjct: 13 NTKHLRKGD--PLPPFNGKLRVYNMRYCPYAQRTILALNAKQIDYEVVNIDLIDKPEWLT 70 Query: 65 KKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVP 124 K+ F VP +E ++ IYES +T EYLDE YP + LLP DP +KA K+I+E + + Sbjct: 71 TKSAFAKVPAIEIAEDVTIYESLVTVEYLDEVYPKRPLLPQDPLKKALDKIIVEASAPIQ 130 Query: 125 SL---VGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWF 181 SL + F + N+E A + K ++E L N+ T F G+ DY+IWPWF Sbjct: 131 SLFIKILKFSDTVNEEHVAA----YHKALDFIQEQLKNRGTVFLDGSEPGYADYMIWPWF 186 Query: 182 ERLEAMKLNECVDHTPK----LKLWMAAMKEDPTVSALLTSEKDWQGFLELY 229 ERL A +E V P L ++ M +D VS L + F E Y Sbjct: 187 ERLRAFAHDERVRLEPSKYSLLLEYIDNMLKDSAVSQYLIPLEILAKFHEAY 238 >3RBT-A nrPDB Length = 246 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 77/232 (33%), Positives = 118/232 (50%), Gaps = 20/232 (8%) Query: 3 GESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEW 62 G S+ G PP P +R+Y + P+ R LVL+AK I++EV ++ PEW Sbjct: 7 GTYFHSVNAGVIPP-PALTDKLRLYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEW 65 Query: 63 FFKKNPFGLVPVLE--NSQG-QLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILEL 119 F KNP +PVLE QG + ++ES + C+YLDE Y L DPY KA ++++E Sbjct: 66 FRAKNPRLKIPVLEIPTDQGDRFLFESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIER 125 Query: 120 FSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP 179 F+++ + GS ++A E+ + E+ LTN+ T +FGGN M+DY++WP Sbjct: 126 FNEL--IKGSL--ECFDTNFAFGSEQIIQTLEIFEKELTNRGTNYFGGNRPGMLDYMVWP 181 Query: 180 WFERLEAMKLNECVDHT---------PKLKLWMAAMKEDPTVSALLTSEKDW 222 W ERL ++ CV+ P W M+ D V S +++ Sbjct: 182 WVERLYLLR---CVNDRKFVEKKSLFPNFADWGDQMQLDDIVKKHAHSPQEY 230 >4QQ7-A nrPDB Length = 207 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 65/206 (31%), Positives = 102/206 (49%), Gaps = 9/206 (4%) Query: 20 PEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQ 79 P + +YS CPF++R RLVL KG+ E+ +++L NKPE NP+G VP+L + Sbjct: 2 PGSMMVLYSGTTCPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILV-ER 60 Query: 80 GQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMIL-----ELFSKVPSLVGSFIRSQ 134 ++YES I EY+DE +P +L+P DP ++A ++ L ELF V +L ++ Sbjct: 61 DLILYESNIINEYIDERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAA 120 Query: 135 NKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVD 194 K ++ + R T+L + K + G SM+D I P RL+ + + Sbjct: 121 EK-NHEKARLAIRDRLTQLAPIFV--KNKYMLGEEFSMLDVAIAPLLWRLDHYGIELSKN 177 Query: 195 HTPKLKLWMAAMKEDPTVSALLTSEK 220 P +K + AL SEK Sbjct: 178 AAPLMKYAERIFSRPAYIEALTPSEK 203 >2VO4-A nrPDB Length = 219 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 58/202 (28%), Positives = 100/202 (49%), Gaps = 9/202 (4%) Query: 33 PFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQGQLIYESAITCE 91 PF R R+ L KGI++E +L+NK + NP +PVL ++ G+ I ES I + Sbjct: 14 PFGMRVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHN-GKPICESLIAVQ 72 Query: 92 YLDEAYPGKK-LLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEF 150 Y++E + + LLP DPY++A + + K +G I + E+ K+EF + Sbjct: 73 YIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEEKEAAKKEFIEAL 132 Query: 151 TKLEEVLTNKKTTFFGGNSISMIDYLIWP---WFERLEAMKLNECVDHTPKLKLWMA-AM 206 LEE L +K T+FGG+++ +D + P WF+ E PK W + Sbjct: 133 KLLEEQLGDK--TYFGGDNLGFVDIALVPFYTWFKAYETFGTLNIESECPKFIAWAKRCL 190 Query: 207 KEDPTVSALLTSEKDWQGFLEL 228 +++ +L +K ++ ++L Sbjct: 191 QKESVAKSLPDQQKVYEFIMDL 212 >4J2F-A nrPDB Length = 223 Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 56/201 (27%), Positives = 90/201 (44%), Gaps = 7/201 (3%) Query: 33 PFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGL-VPVLENSQGQLIYESAITCE 91 PF+ R LK KGI +E + +L NK + NP +PVL + G+ I ES I E Sbjct: 14 PFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVLVHG-GKPICESTIILE 72 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 YLDE +P LLP DP+E+A + ++ + + + R++ +E +K T Sbjct: 73 YLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRTKGEELEKAVKNCLEVLKT 132 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYL---IWPWFERLEAMKLNECVDHT--PKLKLWMAAM 206 E + +FGG+ I ++D I W +E + + ++ P+L W Sbjct: 133 IEEHAMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIEEVAGVKVLESQKFPRLHAWTENF 192 Query: 207 KEDPTVSALLTSEKDWQGFLE 227 KE P + L F + Sbjct: 193 KEAPIIKENLPDRDQMTAFFK 213 >4CHS-A nrPDB Length = 219 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 56/193 (29%), Positives = 92/193 (47%), Gaps = 8/193 (4%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQGQLIYESAITC 90 PF R R+ L KGI +E +L+NK + NP +PVL ++ G+ I ES I Sbjct: 13 SPFGMRVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHN-GKPISESLIAV 71 Query: 91 EYLDEAYPGKK-LLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKE 149 +Y++E + + LLP DPY++A + + +G I + E+ K+EF + Sbjct: 72 QYIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSKGEEKEAAKKEFIEA 131 Query: 150 FTKLEEVLTNKKTTFFGGNSISMIDYLIWP---WFERLEAMKLNECVDHTPKLKLWMAAM 206 LEE L +K T+FGG++I +D + P WF+ E + P+ W Sbjct: 132 LKLLEEQLGDK--TYFGGDNIGFVDIALVPFYTWFKVYETFGSLNIENECPRFVAWAKRC 189 Query: 207 KEDPTVSALLTSE 219 + +V+ L + Sbjct: 190 LQKESVAKSLPDQ 202 >5G5A-A nrPDB Length = 221 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 9/193 (4%) Query: 34 FAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGL-VPVLENSQGQLIYESAITCEY 92 F RTR+ L+ K ++ + +L NK + NP +PVL ++ G + ES I EY Sbjct: 15 FGMRTRIALEEKNVKFDYREQDLWNKSPILLEMNPVHKKIPVLIHN-GNPVCESLIQIEY 73 Query: 93 LDEAYPGKK-LLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 +DE +P K LLP DPY++A K + K I E++ K+EF + Sbjct: 74 IDEVWPSKTPLLPSDPYQRAQAKFWGDFIDKKVYASARLIWGAKGEEHEAGKKEFIEILK 133 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLI---WPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 LE L +K T+FGG + +D + + WFE E PKL W E Sbjct: 134 TLESELGDK--TYFGGETFGYVDIALIGFYSWFEAYEKFGSFSIEAECPKLIAWGKRCVE 191 Query: 209 DPTVS-ALLTSEK 220 +V+ +L SEK Sbjct: 192 RESVAKSLPDSEK 204 >5IQY-A nrPDB Length = 216 Score = 72.0 bits (175), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 46/154 (29%), Positives = 76/154 (49%), Gaps = 11/154 (7%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 CPF++R L L+ K I +E+ ++L NKPEWF K +P G VPV + G+ I +S + + Sbjct: 23 CPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKVPVFNSGDGKWIADSDVITQ 82 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 ++E +P L+ Y K+ PS V F++S++ D G ++ E Sbjct: 83 VIEEKFPTPSLVTPPEYASVGSKIF-------PSFV-KFLKSKDASD--GSEKALLDELQ 132 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLE 185 L+E L + G ++S D + P L+ Sbjct: 133 ALDEHL-KAHGPYISGENVSAADLSLGPKLFHLQ 165 >4PQI-A nrPDB Length = 241 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 70/250 (28%), Positives = 114/250 (45%), Gaps = 36/250 (14%) Query: 1 MSGESA--RSLGKGSAPP-------GPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEV 51 M+ SA +S+ + APP P+ +G+ ++Y+ CPFA+R + KG++ E+ Sbjct: 1 MATASALDKSVPEKLAPPLDATAEQPPLFDGTTKLYTCYTCPFAQRVWITRNFKGLQDEI 60 Query: 52 --ININLKNKPEWFFKK-NPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPY 108 + + L+N+P W+ +K P VP LE++ G++ ES +YL+ + G LLP DP Sbjct: 61 KLVPLILQNRPAWYPEKVYPPNKVPSLEHN-GKITGESLDLIKYLESNFEGPSLLPKDP- 118 Query: 109 EKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKE----FTKLEEVLTN-KKTT 163 A ++ ELFS G+ Y K + KE F LE L Sbjct: 119 --AKKEFAEELFSYTDKFNGTV--------YTAFKGDLAKEAGPAFDHLENALHKFDDGP 168 Query: 164 FFGGNSISMIDYLIWPWFERLEAMKLN----ECVDHTPKLKLWMAAMKEDPTVSALLTSE 219 FF G S++D P+ ERL L + KL W+ + + + A ++ Sbjct: 169 FFLGKEFSLVDIAYIPFVERLNIFLLEVFKYDITAGRQKLAAWIEEVNK---IEAYKQTK 225 Query: 220 KDWQGFLELY 229 D + +E Y Sbjct: 226 TDPKELVEFY 235 >5J5N-A nrPDB Length = 231 Score = 70.1 bits (170), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 55/189 (29%), Positives = 88/189 (46%), Gaps = 8/189 (4%) Query: 33 PFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQGQLIYESAITCE 91 PF R RL L KG+++E +L NK + NP +PVL ++ G+ + ES I + Sbjct: 26 PFGMRVRLALAEKGVKYEYSEEDLWNKSALLLQMNPVNKQIPVLVHN-GKPVCESLIIVQ 84 Query: 92 YLDEAYPGKK-LLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEF 150 Y+DE + LLP DPY++A + + K +G I ++ E+ K++F Sbjct: 85 YIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKKGEEQEAAKKDFIDSL 144 Query: 151 TKLEEVLTNKKTTFFGGNSISMIDYLIWP---WFERLEAMKLNECVDHTPKLKLWMAAMK 207 +E L +K +FGG +I +D + P WF E + PK+ + Sbjct: 145 KLMEGELGDK--PYFGGETIGYVDIALVPFYSWFYAYETIGNFNIEAECPKMIAYCKRCL 202 Query: 208 EDPTVSALL 216 + TVS L Sbjct: 203 QKETVSKAL 211 >6EP7-A nrPDB Length = 220 Score = 70.1 bits (170), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 56/193 (29%), Positives = 91/193 (47%), Gaps = 9/193 (4%) Query: 34 FAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQGQLIYESAITCEY 92 + RTR+ L+ K +++E +L NK + NP +PVL + +G+ I ES I +Y Sbjct: 15 YGMRTRIALEEKKVKYEYREEDLSNKSPLLLQMNPIHKKIPVLIH-EGKPICESIIQVQY 73 Query: 93 LDEAYPGKK-LLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 +DE +P +LP DPY++A + + K + + S++ E K EF + Sbjct: 74 IDELWPDTNPILPSDPYQRAQARFWADYIDKKTYVPCKALWSESGEKQEAAKIEFIEVLK 133 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYL---IWPWFERLEAMKLNECVDHTPKLKLWMA-AMK 207 L+ L +K +FGGN ++D + WF E + V PKL W +K Sbjct: 134 TLDSELGDK--YYFGGNEFGLVDIAFIGFYSWFRTYEEVANLSIVLEFPKLMAWAQRCLK 191 Query: 208 EDPTVSALLTSEK 220 + AL S+K Sbjct: 192 RESVAKALPDSDK 204 >5D9W-A nrPDB Length = 230 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 48/154 (31%), Positives = 78/154 (50%), Gaps = 11/154 (7%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 PF++R L L+ K + +E+ I+++NKP+WF K +P G VPV G+ I +S + + Sbjct: 37 SPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKVPVFNGGDGKWIPDSDVITQ 96 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 ++E YP L+ P E A + SK+ S +F++S++ D G ++ E Sbjct: 97 VIEEKYPTPSLV--TPPEYAS------VGSKIFSCFTTFLKSKDPND--GSEKALLTELQ 146 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLE 185 LEE L F G +IS D + P L+ Sbjct: 147 ALEEHL-KAHGPFINGQNISAADLSLAPKLYHLQ 179 >4AGS-A nrPDB Length = 471 Score = 66.6 bits (161), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 54/189 (28%), Positives = 85/189 (44%), Gaps = 12/189 (6%) Query: 4 ESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWF 63 E+ R L SAP G + +YS FCPF +R RL + + + ++ + L +PEW+ Sbjct: 234 ENYRHLVPESAPMMGANGGHV-LYSNLFCPFVDRARLASELRKFQMHIVEVPLHPQPEWY 292 Query: 64 FKKNPFGLVPVLENSQGQLIYESAITCEYLD-EAYPGKKLLPDDPYEKACQKMILELFSK 122 NP VP L G+ ++ES + +Y+D A G L+P EK + + Sbjct: 293 KYINPRDTVPALFTPSGEAVHESQLIVQYIDCVATKGSALVPRGDAEKEYE--VGFFVEN 350 Query: 123 VPSLVGSFIR--SQNKEDYAGLKEEFRKEFTKLEEVLTNK---KTTFFGGNSISMIDYLI 177 VG + + ED K E + +LE+ L + FFGG ++ D I Sbjct: 351 AGYFVGGLMSWIIRGGED---AKAELQWAAGELEQQLAKHPFGEGPFFGGKRMNAGDVAI 407 Query: 178 WPWFERLEA 186 P+ R +A Sbjct: 408 LPFLVRAKA 416 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 45/179 (25%), Positives = 85/179 (47%), Gaps = 17/179 (9%) Query: 17 GPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK-PEWFFKKNPFGLVPVL 75 G + ++++Y CPF R +V + K + ++ + + L+ + P+W+ + NP VP L Sbjct: 20 GHMAARALKLYVSATCPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPTL 79 Query: 76 E--NSQGQLIYESAITCEYLDEA-YPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIR 132 E N+ + ++ES + +YLD + P L+ A Q+ +E F + VG FI Sbjct: 80 EVGNADKRFMFESMLIAQYLDNSGAPAGALMGSS----AAQRHQIEFFL---AQVGDFIG 132 Query: 133 SQNKEDYAGLKEEFRKEFTK----LEEVLTNKKTT--FFGGNSISMIDYLIWPWFERLE 185 + + L E RK ++ +L +TT ++ +M D + P+ RL+ Sbjct: 133 AAHGLLRDPLSGEKRKAMDDNAAYVDGLLAANQTTGPYYCDGEFTMADVALVPFLVRLK 191 >5ELG-A nrPDB Length = 221 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 43/155 (27%), Positives = 74/155 (47%), Gaps = 11/155 (7%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 CPF++R L L+ K + +++ INL +KP+WF +P G VPVL+ + + +S + Sbjct: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD-KWVTDSDVIVG 78 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 L+E Y PD P + + + S + G+F++S++ D G + E Sbjct: 79 ILEEKY------PDPPLKTPAE--FASVGSNIFGTFGTFLKSKDSND--GSEHALLVELE 128 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEA 186 LE L + F G +S +D + P L+ Sbjct: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQV 163 >2CZ2-A nrPDB Length = 223 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 48/162 (29%), Positives = 77/162 (47%), Gaps = 9/162 (5%) Query: 37 RTRLVLKAKGIRHEVININL-----KNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 R R+ L KGI +E++ INL + E F NP VP L+ G I +S E Sbjct: 26 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID-GITIVQSLAIME 84 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSK--VPSLVGSFIRSQNKEDYAGLKEE-FRK 148 YL+E P +LLP DP ++A +MI +L + P S ++ +E+ ++ Sbjct: 85 YLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITS 144 Query: 149 EFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLN 190 F LE++L + + G+ +SM D + P E K++ Sbjct: 145 GFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD 186 >5ECL-B nrPDB Length = 223 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 55/205 (26%), Positives = 89/205 (43%), Gaps = 8/205 (3%) Query: 34 FAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQGQLIYESAITCEY 92 F R R+ L+ KG+ E + NK + NP +PVL ++ G+ + ES +Y Sbjct: 21 FGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLVHN-GKPVCESLNVVQY 79 Query: 93 LDEAYPGKK-LLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 +DEA+P K P DPY +A + + K + + + E+ K+EF + Sbjct: 80 VDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKGEEQEAGKKEFIEAVK 139 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIW---PWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 LE L +K +FGG+S +D + WF+ E +PKL W E Sbjct: 140 ILESELGDK--PYFGGDSFGYVDISLITFSSWFQAYEKFGNFSIESESPKLIAWAKRCME 197 Query: 209 DPTVSALLTSEKDWQGFLELYLQNS 233 +VS L + + Y +N+ Sbjct: 198 KESVSKSLPDSEKIVAYAAEYRKNN 222 >1FW1-A nrPDB Length = 216 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 53/175 (30%), Positives = 79/175 (45%), Gaps = 25/175 (14%) Query: 37 RTRLVLKAKGIRHEVININL-KNKPEWFFKK----NPFGLVPVLENSQGQLIYESAITCE 91 R R+ L KGI ++ + INL K+ + F K NP VP L+ G I++S E Sbjct: 19 RVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLK-IDGITIHQSLAIIE 77 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKE-- 149 YL+E P +LLP DP ++A +MI +L + G QN + EE + Sbjct: 78 YLEETRPTPRLLPQDPKKRASVRMISDLIA------GGIQPLQNLSVLKQVGEEMQLTWA 131 Query: 150 -------FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTP 197 F LE++L + + G+ ++M D + P E K VD TP Sbjct: 132 QNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFK----VDLTP 182 >1E6B-A nrPDB Length = 221 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 53/169 (31%), Positives = 77/169 (45%), Gaps = 11/169 (6%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEW---FFKKNPFGLVPVLEN 77 E +++YS A R R+ L KG+ +E I +NL ++ F K NP G VP L + Sbjct: 6 EEKLKLYSYWRSSCAHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVD 65 Query: 78 SQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKAC--QKMILELFSKVPSLVGSFIRS-- 133 +I +S YLDE YP LLP D +++A Q M + L P + IR Sbjct: 66 GD-VVINDSFAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIE 124 Query: 134 ---QNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP 179 +E A + K FT LE++L N G+ I + D + P Sbjct: 125 EKINVEEKTAWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAP 173 >5LOL-A nrPDB Length = 215 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 45/154 (29%), Positives = 74/154 (48%), Gaps = 11/154 (7%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 CPF++R L L+ K + ++ IN+ +KP+WF +P G VPV++ G+ + +S + Sbjct: 22 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVK-LDGKWVADSDVIVG 80 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 L+E YP L P E A + SK+ +F++S++ D G ++ E Sbjct: 81 LLEEKYPEPSL--KTPPEFAS------VGSKIFGAFVTFLKSKDAND--GSEKALVDELE 130 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLE 185 LE L F G I+ +D + P LE Sbjct: 131 ALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 164 >1GWC-A nrPDB Length = 230 Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 54/182 (29%), Positives = 91/182 (50%), Gaps = 12/182 (6%) Query: 33 PFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQGQLIYESAITCE 91 PF R +L L KG+ +E + +L K E K NP +PVL ++ G + ES I + Sbjct: 16 PFVTRVKLALALKGLSYEDVEEDLYKKSELLLKSNPVHKKIPVLIHN-GAPVCESMIILQ 74 Query: 92 YLDEAYP--GKKLLPDDPYEKACQKM-ILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRK 148 Y+DE + G LLP DPYE+A + + + K+ + ++R + +E+ + K++ Sbjct: 75 YIDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKTEEEKSEGKKQAFA 134 Query: 149 EFTKLEEVL--TNKKTTFFGGNSISMIDYL---IWPWFERLEAMKLNECVD--HTPKLKL 201 LE L +K FFGG+ + ++D + W + EA+ ++ D TP L Sbjct: 135 AVGVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSWMKVTEALSGDKIFDAAKTPLLAA 194 Query: 202 WM 203 W+ Sbjct: 195 WV 196 >3IBH-A nrPDB Length = 233 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 61/210 (29%), Positives = 83/210 (39%), Gaps = 23/210 (10%) Query: 26 IYSMRFCPFAERTRLVLKAKGIRHEV--ININL----KNKPEWFFKKNPFGLVPVLENSQ 79 IY P+ R R+ L K + V + INL KPE F KN G VPVLE Sbjct: 21 IYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPE-FLAKNYSGTVPVLELDD 79 Query: 80 GQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMI-----LELFSKV--------PSL 126 G LI E EY+D L P EK M+ LEL V P L Sbjct: 80 GTLIAECTAITEYIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGL 139 Query: 127 VGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEA 186 QNKE +++ + VL ++ + G+S SM D + Sbjct: 140 GPEVELYQNKEWGLRQRDKALHGMHYFDTVL--RERPYVAGDSFSMADITVIAGLIFAAI 197 Query: 187 MKLNECVDHTPKLKLWMAAMKEDPTVSALL 216 +KL + + L+ W M++ P+V LL Sbjct: 198 VKL-QVPEECEALRAWYKRMQQRPSVKKLL 226 >4MK3-A nrPDB Length = 226 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 47/88 (53%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL 82 S+++Y+ + P+A + R+VL K I +E+I N+ + + NP G VP L G Sbjct: 22 SMKLYASQTSPYARKVRVVLAEKKIDYEMIEENVWSPDTTIGRFNPLGKVPCLVMEDGGA 81 Query: 83 IYESAITCEYLDEAYPGKKLLPDDPYEK 110 +++S + EY D P +L+P E+ Sbjct: 82 VFDSRVIAEYADTLSPVSRLIPQGSRER 109 >3UBL-A nrPDB Length = 242 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 34/106 (32%), Positives = 59/106 (55%), Gaps = 6/106 (5%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLI 83 I+++ + + +L + KG+ +E I I ++ E F K +P G +PVLE G+ I Sbjct: 4 IKLHGASISNYVNKVKLGILEKGLEYEQIRIA-PSQEEDFLKISPMGKIPVLE-MDGKFI 61 Query: 84 YESAITCEYLDEAYPGK-KLLPDDPYEKACQK---MILELFSKVPS 125 +ES E+LD +P KL+P+DP+E A + I+E + +P+ Sbjct: 62 FESGAILEFLDTIFPQTPKLIPEDPWEAARVREISTIIETYLDIPA 107 >5N9U-A nrPDB Length = 218 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 43/155 (27%), Positives = 71/155 (45%), Gaps = 12/155 (7%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 CPF +R L L+ K I ++ INL +KP+WF + +P G VPV++ + + +S + Sbjct: 20 CPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKVPVVKIDD-KWVADSDVIVG 78 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 L+E P L + K+ PS V F++S++ D G ++ +E Sbjct: 79 ILEEKNPEPPLATPPEFASVGSKIF-------PSFV-KFLKSKDPND--GTEQALLEELK 128 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEA 186 L+ L F G I+ +D + P LE Sbjct: 129 ALDGHL-KVHGPFIAGEKITAVDLSLAPKLYHLEV 162 >4IGJ-A nrPDB Length = 242 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 43/168 (25%), Positives = 79/168 (47%), Gaps = 13/168 (7%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEW---FFKKNPFGLVPVLE--- 76 ++R+YS A R RL L KG+ +E ++L + ++ +NP VPVLE Sbjct: 24 TLRLYSYWRSSSAWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEE 83 Query: 77 NSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILE-LFSKVPSLVGSFIRSQN 135 + + L+ +S E+L+E +P LLP D + +A + + E + S + + + Sbjct: 84 DGRTHLLVQSMAILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRML 143 Query: 136 KEDYAGLKEEFRKEF-----TKLEEVLTNKKTTFFGGNSISMID-YLI 177 +E G E+ + F LE + + F G++ ++ D YL+ Sbjct: 144 REKVPGWDREWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLV 191 >4PXO-A nrPDB Length = 238 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 51/174 (29%), Positives = 84/174 (48%), Gaps = 19/174 (10%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL----KNKPEWFFKKNPFGLVPVLENSQ 79 +++Y A R R+ L KGI +E + ++L ++KP+ F NP G VP L + Sbjct: 24 VKMYGNWRSAAAFRVRIALNLKGIAYEEVFLDLDAGDQHKPD-FLAINPQGAVPALFDGD 82 Query: 80 GQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFS-KVPSLVGSFIRSQNKED 138 G + +S +YL+E G LLP++P +A + + ++ + L +R+ E+ Sbjct: 83 GPPLTQSLAILDYLEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFLMEN 142 Query: 139 YAGLKEEFRKEFTK---------LEEVLTNKKTT--FFGGNSISMIDY-LIWPW 180 Y GL E EF + LE L+N+ T F G+++S D LI W Sbjct: 143 Y-GLPRERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISLW 195 >6JWK-A nrPDB Length = 222 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 3/91 (3%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWF---FKKNPFGLVPVLENSQG 80 +++YS + R R+ L KG+ ++V+ +NL+ + ++NP G +P L ++ G Sbjct: 1 MQLYSFFNSSTSYRVRIALALKGLDYQVVPVNLRQGEQLRPADRQRNPMGALPTLVDADG 60 Query: 81 QLIYESAITCEYLDEAYPGKKLLPDDPYEKA 111 + +S +YLD P +L+P DP +A Sbjct: 61 RRFSQSLAIIDYLDAVQPEPRLIPLDPLHRA 91 >3M3M-A nrPDB Length = 210 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 48/195 (24%), Positives = 87/195 (44%), Gaps = 25/195 (12%) Query: 37 RTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYL 93 + +L+L G+ +E +++ + E F KNP G +PVLE G ++ES +L Sbjct: 17 KIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLELEDGTCLWESNAILNFL 76 Query: 94 DEAYPGKKLLPDDP--YEKACQKMILELFSKVPSL-VGSFIRSQNKEDYAGLKEEFRKEF 150 + G + LP +P + Q E +S P + V FI+ Y GL EE R+E+ Sbjct: 77 AD---GSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQL-----YEGLPEERREEY 128 Query: 151 TKLE-------EVLTNK--KTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKL 201 KL +V+ + +T + G S+ D ++ + + + + P ++ Sbjct: 129 LKLHKRGYKALDVMEKQLSRTPYLVGEHYSIADIALYAYTHVADEGGFD--LSRYPGIQA 186 Query: 202 WMAAMKEDPTVSALL 216 WM ++ P +L Sbjct: 187 WMQRVQSHPRHVPML 201 >3PR8-A nrPDB Length = 229 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 52/224 (23%), Positives = 101/224 (45%), Gaps = 28/224 (12%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL 82 S+++Y + +L L KG+ E + P+ + +P G VPVLE G Sbjct: 2 SLKLYGFSVSNYYNMVKLALLEKGLTFEEVTFYGGQAPQAL-EVSPRGKVPVLETEHG-F 59 Query: 83 IYESAITCEYLDEAYPGKKLLPDDPYEKACQKMIL---ELFSKVPSLVGSFIRSQNKEDY 139 + E+++ +Y+++ GK LLP DP+ +A + +L EL+ ++P+ R+ E + Sbjct: 60 LSETSVILDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPA------RTCYAESF 113 Query: 140 AGL------KEEFRKE----FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMK- 188 G+ KE+ R + F L+ + + G +++ D + + A+ Sbjct: 114 FGMSVEPLIKEKARADLLAGFATLKR--NGRFAPYVAGEQLTLADLMFCFSVDLANAVGK 171 Query: 189 --LN-ECVDHTPKLKLWMAAMKEDPTVSALLTS-EKDWQGFLEL 228 LN + + P+ K + M E+P + +L E F+E+ Sbjct: 172 KVLNIDFLADFPQAKALLQLMGENPHMPRILADKEASMPAFMEM 215 >4PNG-A nrPDB Length = 229 Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 20/198 (10%) Query: 26 IYSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLENSQGQL 82 +Y + P +L L A + +E + +N + K E F KKNP VP LE+ G Sbjct: 12 LYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLED-DGHY 70 Query: 83 IYESAITCEYLDEAYPGK--KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYA 140 I++S YL Y GK L P D ++A L S V + + +RS K +A Sbjct: 71 IWDSHAIIAYLVSKY-GKTDSLYPKDLLQRAVVDQRLHFESGV--IFANALRSITKPLFA 127 Query: 141 GLKEEFRKE--------FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNEC 192 G + KE + LE+ L + GN +++ D+ I LE + Sbjct: 128 GKQTMIPKERYDAIIEVYDFLEKFLAGND--YVAGNQLTIADFSIISTVSSLEVFVKVDT 185 Query: 193 VDHTPKLKLWMAAMKEDP 210 + P++ W +++ P Sbjct: 186 TKY-PRIAAWFKRLQKLP 202 >4YH2-A nrPDB Length = 222 Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 44/197 (22%), Positives = 88/197 (44%), Gaps = 14/197 (7%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEW---FFKKNPFGLVPVLENSQG 80 + +Y + P +L L A + +E +N+++ + + + +KNP VP LE+ G Sbjct: 4 LTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDD-G 62 Query: 81 QLIYESAITCEYLDEAYP-GKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKED- 138 I++S YL Y L P DP ++A L S V + + IRS +K Sbjct: 63 HYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGV--VFANGIRSISKSVL 120 Query: 139 YAGLKEEFRKEFTKLEEVLTNKKT-----TFFGGNSISMIDYLIWPWFERLEAMKLNECV 193 + G + ++ + + E+ +T + GN +++ D+ + LEA + Sbjct: 121 FQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTT 180 Query: 194 DHTPKLKLWMAAMKEDP 210 + P++ W+ +++ P Sbjct: 181 KY-PRIGAWIKKLEQLP 196 >1OYJ-A nrPDB Length = 231 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 27/74 (36%), Positives = 43/74 (58%), Gaps = 3/74 (4%) Query: 33 PFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGL-VPVLENSQGQLIYESAITCE 91 PF +R R+ + KG+ E +L NK + + NP +PVL ++ G+ + ES + + Sbjct: 16 PFGQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVHRKIPVLLHA-GRPVSESLVILQ 74 Query: 92 YLDEAYPGK-KLLP 104 YLD+A+PG LLP Sbjct: 75 YLDDAFPGTPHLLP 88 >3R2Q-A nrPDB Length = 202 Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 34/125 (27%), Positives = 54/125 (43%) Query: 33 PFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEY 92 PF + ++L KGI E IN N + NP G VPVL +G+ ++S I EY Sbjct: 10 PFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECWFDSPIIAEY 69 Query: 93 LDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTK 152 ++ +LP DP E + I L + +R Q + ++E ++ K Sbjct: 70 IELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSEDELLRQREK 129 Query: 153 LEEVL 157 + L Sbjct: 130 INRSL 134 >3NIV-A nrPDB Length = 222 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 30/83 (36%), Positives = 44/83 (53%), Gaps = 6/83 (7%) Query: 37 RTRLVLKAKGIRHEVININLKN-----KPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 R R+ L K I +E I ++L N + + NP LVP L+ GQ++ +S + Sbjct: 16 RVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLD-INGQILSQSMAIID 74 Query: 92 YLDEAYPGKKLLPDDPYEKACQK 114 YL+E +P LLP DP+ KA K Sbjct: 75 YLEEIHPEMPLLPKDPFMKATLK 97 >2IL3-A nrPDB Length = 221 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 56/202 (27%), Positives = 86/202 (42%), Gaps = 24/202 (11%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKN----KPEWFFKKNPFGLVPVLENS 78 ++ +Y++ P L KA G+ E INL KPE F K NP +PVL+++ Sbjct: 3 NLVLYTLHLSPPCRAVELTAKALGLELEQKTINLLTGDHLKPE-FVKLNPQHTIPVLDDN 61 Query: 79 QGQLIYESAITCEYLDEAYPGK--KLLPDDPYEKACQKMILELFSKVPSLVGSFI----- 131 G +I ES YL Y GK L P DP ++A L S V FI Sbjct: 62 -GTIITESHAIMIYLVTKY-GKDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERIL 119 Query: 132 ---RSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMK 188 +S ED E +K + LE+ L + F G ++++ D+ + + Sbjct: 120 FFGKSDIPEDRV---EYVQKSYELLEDTLVDD---FVAGPTMTIADFSCISTISSIMGVV 173 Query: 189 LNECVDHTPKLKLWMAAMKEDP 210 E H P++ W+ +K+ P Sbjct: 174 PLEQSKH-PRIYAWIDRLKQLP 194 >2PMT-A nrPDB Length = 203 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 44/188 (23%), Positives = 84/188 (44%), Gaps = 11/188 (5%) Query: 39 RLVLKAKGIRHEVININLKNKP----EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLD 94 +VL+ G+ + I+L+ K + F NP G VPVL+ G ++ E +YL Sbjct: 15 HIVLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVLQLDNGDILTEGVAIVQYLA 74 Query: 95 EAYPGKKLL-PDDPYEKACQKMILE-LFSKVPSLVGSFIRSQNKEDYA-GLKEEFRKEFT 151 + P + L+ P E+ Q L L S+V S E Y +K + + +F Sbjct: 75 DLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPLFSSDTPESYLPVVKNKLKSKFV 134 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPT 211 + +VL+ +K G+ ++ D ++ + + L+ + L+ ++A + + P Sbjct: 135 YINDVLSKQKCV--CGDHFTVADAYLFTLSQWAPHVALD--LTDLSHLQDYLARIAQRPN 190 Query: 212 VSALLTSE 219 V + L +E Sbjct: 191 VHSALVTE 198 >3TOT-A nrPDB Length = 226 Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 38/78 (48%) Query: 33 PFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEY 92 P+ + R+VL K I ++ + ++ N + NP G VP L G +++S + EY Sbjct: 12 PYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQFNPLGKVPCLVMDDGGALFDSRVIAEY 71 Query: 93 LDEAYPGKKLLPDDPYEK 110 D P +L+P E+ Sbjct: 72 ADTLSPVARLIPPSGRER 89 >3VWX-A nrPDB Length = 222 Score = 43.5 bits (101), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 57/203 (28%), Positives = 88/203 (43%), Gaps = 22/203 (10%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLENS 78 G + +Y + P L LKA + E +NL K E + KKNP VP LE Sbjct: 2 GKLVLYGIDPSPPVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLEED 61 Query: 79 QGQLIYESAITCEYLDEAYPGK--KLLPDDPYEKAC--QKMILE---LFSKVPSLVGS-- 129 G LI++S YL Y GK L P D ++A Q+M E LF + + Sbjct: 62 -GHLIWDSHAIMAYLVSKY-GKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPL 119 Query: 130 FIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKL 189 F R+Q + + + + + LE L N K + G+ +++ D+ I L A Sbjct: 120 FFRNQTQIPQHQI-DSIVESYGFLESFLKNNK--YMAGDHLTIADFSIVTSVTSLVAFA- 175 Query: 190 NECVDHT--PKLKLWMAAMKEDP 210 +D + PKL W+ +++ P Sbjct: 176 --EIDQSKFPKLSAWLKSLQSLP 196 >3M8N-A nrPDB Length = 225 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 38/197 (19%), Positives = 86/197 (43%), Gaps = 16/197 (8%) Query: 25 RIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQGQ 81 ++YSM+ + + RL L + + +++ +++ F KNP G VP+LE + G+ Sbjct: 5 KLYSMQRSGNSYKVRLALALLDAPYRAVEVDILRGESRTPDFLAKNPSGQVPLLETAPGR 64 Query: 82 LIYESAITCEYLDEAYPGKKLLPDDPYEK--ACQKMILELFSKVPSLVGSF-----IRSQ 134 + ES YL G L PD ++ A Q M E + P++ ++ ++ Sbjct: 65 YLAESNAILWYLA---VGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKGG 121 Query: 135 NKEDYAGLKEEFRKEFTKLEEVLTNKKTT-FFGGNSISMIDYLIWPWFERLEAMKLNECV 193 L++ + + L+ + + KT +F +++ D ++ + + + + Sbjct: 122 RDLQTHALEDWLERGYAALQVMENHLKTNDYFAAGQLTIADIALYGYTHVADQCDFD--L 179 Query: 194 DHTPKLKLWMAAMKEDP 210 P + W+ +++ P Sbjct: 180 STFPAVNAWLRRVEQTP 196 >5NR1-A nrPDB Length = 228 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 40/159 (25%), Positives = 68/159 (42%), Gaps = 18/159 (11%) Query: 33 PFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQ---LIYESAIT 89 P + + RL L K + + + P F NP G+ PVL ++ Q +I E+ Sbjct: 14 PASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMPPVLVETKHQRNLVICETRAI 73 Query: 90 CEYLDEAYPGKKLLPDDPYEKACQKMILELFS-KVPSLVGSFIRSQNKE---------DY 139 E+++E LL DP E+A + +L+ F K + V F+ + E D Sbjct: 74 LEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGFLLHEKMEKRLLRMGAPDL 133 Query: 140 AGL---KEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDY 175 A L +E R +E +L + + G +S+ D+ Sbjct: 134 AALRQGREALRMHLGYIESLLQTRD--WLAGRRMSLADF 170 >2JL4-A nrPDB Length = 213 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 +++Y+ + R R+ L KG+ +E + ++L ++ + F NP LVP L+ Sbjct: 2 MKLYNFWRSGTSHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTG-A 60 Query: 81 QLIYESAITCEYLDEAYPGKKLLPDD 106 Q++ +S E+L+E YP LLP D Sbjct: 61 QVLIQSPAIIEWLEEQYPTPALLPAD 86 >2FHE-A nrPDB Length = 216 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 44/191 (23%), Positives = 86/191 (45%), Gaps = 18/191 (9%) Query: 38 TRLVLKAKGIRHEVININLKNKPEWFFKKNPFGL----VPVLENSQGQLIYESAITCEYL 93 RL+L+ G ++E + +WF KK GL +P + + +L AI Sbjct: 16 VRLLLEYLGEKYEEQIYERDDGEKWFSKKFELGLDLPNLPYYIDDKCKLTQSLAILRYIA 75 Query: 94 DEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKL 153 D+ ++ E+A MI L R + + LKE + K+ Sbjct: 76 DK----HGMIGTTSEERARVSMIE---GAAVDLRQGISRISYQPKFEQLKEGYLKDLPTT 128 Query: 154 EEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEAMKLNE--CVDHTPKLKLWMAAMKED 209 ++ ++ K + G S+S +D+++ +E L+A++ E C+DH P L+ +M+ ++ Sbjct: 129 MKMWSDFLGKNPYLRGTSVSHVDFMV---YEALDAIRYLEPHCLDHFPNLQQFMSRIEAL 185 Query: 210 PTVSALLTSEK 220 P++ A + S + Sbjct: 186 PSIKAYMESNR 196 >1AW9-A nrPDB Length = 216 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 6/86 (6%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 +++Y M P R VL KG+ E++ ++L +K F NPFG +P L + Sbjct: 3 LKLYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDGD- 61 Query: 81 QLIYESAITCEYLDEAYP--GKKLLP 104 ++++ES Y+ Y G LLP Sbjct: 62 EVLFESRAINRYIASKYASEGTDLLP 87 >5A5K-A nrPDB Length = 212 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 47/207 (22%), Positives = 83/207 (40%), Gaps = 20/207 (9%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKN---KPEWFFKKNPFGLVPVLENS 78 I+++ R + L K + E++++ LK+ K E F +NPFG VP E+ Sbjct: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 Query: 79 QGQLIYESAITCEYLDEAY--PGKKLLPDDPYEKACQKMILELFSKVPS-----LVGSFI 131 +L AIT +Y+ Y G LL D + Q I+ + +V + Sbjct: 62 DLKLFESRAIT-QYIAHRYENQGTNLLQTDS-KNISQYAIMAIGMQVEDHQFDPVASKLA 119 Query: 132 RSQNKEDYAGLKEE---FRKEFTKLEEVLTN-----KKTTFFGGNSISMIDYLIWPWFER 183 Q + GL + +E KL +VL K+ + G + ++ D P + Sbjct: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY 179 Query: 184 LEAMKLNECVDHTPKLKLWMAAMKEDP 210 L + P++ W+A + + P Sbjct: 180 LLGTPTKKLFTERPRVNEWVAEITKRP 206 >3UAR-A nrPDB Length = 227 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 4/70 (5%) Query: 39 RLVLKAKGIRHEVININLKNKPEW----FFKKNPFGLVPVLENSQGQLIYESAITCEYLD 94 +VL+ G+ E+ N++L K F + NP G VP L+ GQ++ E + +YL Sbjct: 17 HIVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQLDDGQVLTEDQVILQYLA 76 Query: 95 EAYPGKKLLP 104 + P L+P Sbjct: 77 DLKPESGLMP 86 >2PVQ-A nrPDB Length = 201 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 16/178 (8%) Query: 39 RLVLKAKGIRHEVININLKNKPEW----FFKKNPFGLVPVLENSQGQLIYESAITCEYLD 94 ++L G+ +E+ ++LK K +F NP G VP LE G +I ++A +Y+ Sbjct: 15 HIILSEAGLPYELEAVDLKAKKTADGGDYFAVNPRGAVPALEVKPGTVITQNAAILQYIG 74 Query: 95 EAYPGKKLLPD-DPYEKACQKMILELFSKV-PSLVGSFIRSQNKEDYAGLKEEFRKEFTK 152 + P E+A + L S + + G F + ++E AG+ + + Sbjct: 75 DHSDVAAFKPAYGSIERARLQEALGFCSDLHAAFSGLFAPNLSEEARAGVIANINRRLGQ 134 Query: 153 LEEVLTNKKTTFFGGNSISMIDY----LIWPWFERLE------AMKLNECVDHTPKLK 200 LE +L++K + G + Y + W ++L+ A+KL E V P ++ Sbjct: 135 LEAMLSDKNAYWLGDDFTQPDAYASVIIGWGVGQKLDLSAYPKALKLRERVLARPNVQ 192 >1F2E-A nrPDB Length = 201 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 44/199 (22%), Positives = 77/199 (38%), Gaps = 33/199 (16%) Query: 39 RLVLKAKGIRHEVININLKNKP----EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLD 94 + L+ G E + ++L + E F NP G VP L G+ + E+ Y+ Sbjct: 15 HIALRETGADFEAVKVDLAVRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILLYIA 74 Query: 95 EAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGS---------FIRSQNKEDYAGLKEE 145 + P L P E + + L S++ S +GS F + + E A E Sbjct: 75 DQNPASGLA---PAEGSLDRY--RLLSRL-SFLGSEFHKAFVPLFAPATSDEAKAAAAES 128 Query: 146 FRKEFTKLEEVLTNKKTTFFGGNSISMID-----YLIWPWFERLEAMKLNECVDHTPKLK 200 + L++ L + + GN+ S+ D L WP + ++ + P L Sbjct: 129 VKNHLAALDKELAGRD--HYAGNAFSVADIYLYVMLGWPAYVGID-------MAAYPALG 179 Query: 201 LWMAAMKEDPTVSALLTSE 219 + + + P V A L +E Sbjct: 180 AYAGKIAQRPAVGAALKAE 198 >2GDR-A nrPDB Length = 202 Score = 40.0 bits (92), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 4/72 (5%) Query: 39 RLVLKAKGIRHEVININLKNKP----EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLD 94 + L+ G+ E++ ++L +K + + + NP G VP L+ G+ + E +Y+ Sbjct: 15 HIALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCLQLDDGRTLTEGPAIVQYVA 74 Query: 95 EAYPGKKLLPDD 106 + PGK+L P + Sbjct: 75 DQVPGKQLAPAN 86 >4MDC-A nrPDB Length = 252 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 4/99 (4%) Query: 26 IYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYE 85 +Y P + RL+L G + E+ F NP G +PV + + + Sbjct: 26 LYHHPMSPASRFVRLILSEYGYQTELSEEQPWENRRDFLTLNPAGTLPVYVDDSMRALCG 85 Query: 86 SAITCEYLDEAY----PGKKLLPDDPYEKACQKMILELF 120 + I EYLDE ++LL +DP+++A + + E F Sbjct: 86 ATIISEYLDETSGIMKRDRRLLAEDPFQRAEIRRLTEWF 124 >5F07-A nrPDB Length = 213 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 22/212 (10%) Query: 24 IRIY--SMRFCPFAERTRLVLKAKGIRHEVININLKNK----PEWFFKKNPFGLVPVLEN 77 +++Y ++ CP +R L KG+ ++++++L + PE F K PFG VPV+E+ Sbjct: 2 VKVYGPAVAVCP--QRVMACLLEKGVEFDLVHVDLDSGEQKLPE-FLLKQPFGQVPVVED 58 Query: 78 SQGQLIYESAITCEYLDEAYP--GKKLLPDDPYEKACQKMILEL----FSKVPSLVGSFI 131 +L +ES Y Y G LL + EKA LE+ F+ + + + Sbjct: 59 GDFKL-FESRAIIRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIEAHNFNDLVFNIVFQV 117 Query: 132 RSQNKEDYAGLKEEFRKEFTKLEEVLTN-----KKTTFFGGNSISMIDYLIWPWFERL-E 185 + G E R KLE+VL K+ + G+S ++ D P L Sbjct: 118 VILPRIGQQGDSELVRTYEEKLEKVLDVYEKRLSKSKYLAGDSFTLADLSHLPATRYLVN 177 Query: 186 AMKLNECVDHTPKLKLWMAAMKEDPTVSALLT 217 L V KL W + P L+ Sbjct: 178 EAGLGHLVKDRKKLNAWWEDISSRPAWKKLMN 209 >4PTS-A nrPDB Length = 348 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 46/204 (22%), Positives = 84/204 (41%), Gaps = 35/204 (17%) Query: 18 PVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININL----KNKPEWFFKKNPFGLVP 73 PV G R+ + R CP+A RT +V + G+ + V+++ L +K W F +P G+ P Sbjct: 42 PVEPGRYRLIAARACPWANRTLIVRRLLGLEN-VLSLGLCGPTHDKNSWTFDLDPGGVDP 100 Query: 74 VLENSQGQLIYE-------SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSK--VP 124 VL + + YE IT + E G+ + D P + + + P Sbjct: 101 VLGIPRLKDAYEKRFPGYPKGITVPAVVEIATGEVVTNDFPQITIDFSLEWTAYHRDGAP 160 Query: 125 SLVGSFIRSQNKEDYAGLKEE--------------------FRKEFTKLEEVLTN-KKTT 163 L +R++ E G+ E + + FTKL+E+ + Sbjct: 161 QLYPEHLRAEIDEVSKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLFTKLDELSERLAQQR 220 Query: 164 FFGGNSISMIDYLIWPWFERLEAM 187 + G++I+ D ++ R +A+ Sbjct: 221 YLVGDTITEADVRLFTTLARFDAV 244 >2D2Z-A nrPDB Length = 261 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 43/181 (23%), Positives = 75/181 (41%), Gaps = 7/181 (3%) Query: 28 SMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESA 87 S+ CPF++R ++L KG+ V ++LK KP P G P ++ + Sbjct: 31 SIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPPFITFNSEVKTDVN 89 Query: 88 ITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFR 147 E+L+E K L P +++F+K ++I++ E L+ Sbjct: 90 KIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAK----FSAYIKNSRPEANEALERGLL 145 Query: 148 KEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMK 207 K KL+E L + NS+ I + + + E M L +C + PKL + K Sbjct: 146 KTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNE-MTLADC-NLLPKLHIVKVVAK 203 Query: 208 E 208 + Sbjct: 204 K 204 >5F06-A nrPDB Length = 216 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 46/204 (22%), Positives = 80/204 (39%), Gaps = 18/204 (8%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 +++Y R L K + E++ ++L ++K F KNPFG +P LE Sbjct: 2 LKLYGAPMSTCTSRVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDL 61 Query: 81 QLIYESAITCEYLDEAYPGKK---LLPDDPYEKACQKMILELFSK-----VPSLVGSFIR 132 L AIT Y+ E + G + ++ E A K+ E+ S + +V F+ Sbjct: 62 TLFESRAITS-YIAEKFKGTGYDLIRHENLKEAASVKVWTEVESHRYNPAIAPIVFQFMV 120 Query: 133 S---QNKEDYAGLKEEFRKEFTKLEEVLTNK--KTTFFGGNSISMIDYLIWPWFERLEAM 187 + N D + + K K+ ++ K T + G+ S+ D P+ L Sbjct: 121 APLRGNSPDQTIIDDNVEK-LGKVLDIYEAKLSSTKYLAGDFYSLADLHHLPYTYYLMKT 179 Query: 188 KLNECVDHTPKLKLWMAAMKEDPT 211 V+ P +K W + P Sbjct: 180 PAASVVNERPHVKAWWEDISSRPA 203 >3M1G-A nrPDB Length = 362 Score = 35.8 bits (81), Expect = 0.015, Method: Compositional matrix adjust. Identities = 46/206 (22%), Positives = 83/206 (40%), Gaps = 39/206 (18%) Query: 18 PVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPE----WFFKKNPFGLVP 73 PV G R+ + R CP+A RT + + G+ + VI++ L W F +P L P Sbjct: 56 PVEAGRYRLVAARACPWAHRTVITRRLLGLEN-VISLGLTGPTHDVRSWTFDLDPNHLDP 114 Query: 74 VLENSQGQLI-------YESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSK--VP 124 VL+ + Q Y IT L E K + D P + + F + P Sbjct: 115 VLQIPRLQDAYFNRFPDYPRGITVPALVEESSKKVVTNDYPSITIDFNLEWKQFHREGAP 174 Query: 125 SLVGSFIRSQ----------------NKEDYAGLKEEFRKEFTK-------LEEVLTNKK 161 +L + +R + + +AG +E + + + LE+ L+ ++ Sbjct: 175 NLYPAELREEMAPVMKRIFTEVNNGVYRTGFAGSQEAHNEAYKRLWVALDWLEDRLSTRR 234 Query: 162 TTFFGGNSISMIDYLIWPWFERLEAM 187 + G+ I+ D ++P R +A+ Sbjct: 235 --YLMGDHITEADIRLYPTLVRFDAV 258 >4Q5F-A nrPDB Length = 218 Score = 35.8 bits (81), Expect = 0.015, Method: Compositional matrix adjust. Identities = 48/215 (22%), Positives = 87/215 (40%), Gaps = 29/215 (13%) Query: 17 GPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLE 76 G +P+ + + +R E RL+ G++ E + ++ P K PFG +P+LE Sbjct: 11 GSMPQYKLTYFDIR--GLGEGARLIFHQAGVKFEDNRLKREDWPA-LKPKTPFGQLPLLE 67 Query: 77 NSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNK 136 G+++ +SA YL + L P E+A I + F + + R Sbjct: 68 -VDGEVLAQSAAIYRYLGRQF---GLAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAG 123 Query: 137 EDYAGLKEEFRKEFTK---------LEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEA- 186 + G KE+ KE LE+ L + + G S++ D +I E+ Sbjct: 124 FE-EGDKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESL 182 Query: 187 --------MKLNECVDHT---PKLKLWMAAMKEDP 210 ++L + ++H P +K W+A + P Sbjct: 183 IPDFLSGHLQLKKYIEHVRELPNIKKWIAERPKTP 217 >2R5G-A nrPDB Length = 247 Score = 35.8 bits (81), Expect = 0.017, Method: Compositional matrix adjust. Identities = 35/168 (20%), Positives = 67/168 (39%), Gaps = 21/168 (12%) Query: 28 SMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESA 87 S+ CPF +R ++L KG++ V +++ KPE P G P +L + Sbjct: 26 SIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAP-GTNPPFLVYNKELKTDFI 84 Query: 88 ITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFR 147 E+L++ + P K + LF+K ++I++ KE ++ Sbjct: 85 KIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAK----FSAYIKNTQKEANKNFEKSLL 140 Query: 148 KEFTKLEEVLTN----------------KKTTFFGGNSISMIDYLIWP 179 KEF +L++ L + F G+ +++ D + P Sbjct: 141 KEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLP 188 >1N2A-A nrPDB Length = 201 Score = 35.8 bits (81), Expect = 0.019, Method: Compositional matrix adjust. Identities = 45/198 (22%), Positives = 85/198 (42%), Gaps = 19/198 (9%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKP----EWFFKKNPFGLVPVLENSQGQLIYESA 87 C A + + L+ G +++++L K + +F NP G VP L G L+ E Sbjct: 10 CSLA--SHITLRESGKDFTLVSVDLMKKRLENGDDYFAVNPKGQVPALLLDDGTLLTEGV 67 Query: 88 ITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGS----FIRSQNKEDYA-GL 142 +YL ++ P ++LL P + +E + + + + R E+Y + Sbjct: 68 AIMQYLADSVPDRQLLA--PVNSISRYKTIEWLNYIATELHKGFTPLFRPDTPEEYKPTV 125 Query: 143 KEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLN-ECVDHTPKLKL 201 + + K+ + E L K + G ++ D ++ A+KLN E ++H + Sbjct: 126 RAQLEKKLQYVNEAL--KDEHWICGQRFTIADAYLFTVLRWAYAVKLNLEGLEH---IAA 180 Query: 202 WMAAMKEDPTVSALLTSE 219 +M M E P V L++E Sbjct: 181 FMQRMAERPEVQDALSAE 198 >3C8E-A nrPDB Length = 288 Score = 35.4 bits (80), Expect = 0.020, Method: Compositional matrix adjust. Identities = 44/184 (23%), Positives = 75/184 (40%), Gaps = 26/184 (14%) Query: 18 PVPEGSIRIYSMRFCPFAERTR------LVLKAKGIRHEVININLKNKPEW---FFKKNP 68 PV + +++YS+ P ++ L L G ++ I + + ++ F + NP Sbjct: 39 PVGKHPLQLYSLG-TPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNP 97 Query: 69 FGLVPVLENSQGQ---LIYESAITCEYLDEAYPGKKLLPDDPYEKA-CQKMILELFSKVP 124 +P L + ++ES YL E + LP D ++ + L P Sbjct: 98 NSKIPALRDHTHNPPIRVFESGSILLYLAEKF--GYFLPQDLAKRTETMNWLFWLQGAAP 155 Query: 125 SLVGSFIRSQNKEDYAGLKEE-----FRKEFTKLEEVLTNK--KTTFFGGNSISMIDYLI 177 L G F + YA +K E F E +L +VL + + F G+ ++ D I Sbjct: 156 FLGGGFGHFYH---YAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAI 212 Query: 178 WPWF 181 WPWF Sbjct: 213 WPWF 216 >2WRT-A nrPDB Length = 218 Score = 35.0 bits (79), Expect = 0.025, Method: Compositional matrix adjust. Identities = 38/171 (22%), Positives = 77/171 (45%), Gaps = 18/171 (10%) Query: 58 NKPEWFFKKNPFGL----VPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQ 113 ++ +W K GL +P + + +L AI D+ +L P E+A Sbjct: 37 DREKWLGDKFNMGLDLPNLPYYIDDKCKLTQSVAIMRYIADK----HGMLGSTPEERARI 92 Query: 114 KMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTN--KKTTFFGGNSIS 171 MI L F+R + +K ++ KE ++ +N + G+S+S Sbjct: 93 SMIE---GAAMDLRMGFVRVCYNPKFEEVKGDYLKELPTTLKMWSNFLGDRHYLTGSSVS 149 Query: 172 MIDYLIWPWFERLEAMKL--NECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 +D+++ +E L+ ++ +C++ PKLK + + +++ P + A + SEK Sbjct: 150 HVDFMV---YEALDCIRYLAPQCLEDFPKLKEFKSRIEDLPKIKAYMESEK 197 >1AXD-A nrPDB Length = 209 Score = 34.7 bits (78), Expect = 0.036, Method: Compositional matrix adjust. Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 29/196 (14%) Query: 37 RTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQGQL-IYESAITCEY 92 R L+ G +E++ IN ++K +NPFG VP L++ G L ++ES C+Y Sbjct: 16 RCATALEEAGSDYEIVPINFATAEHKSPEHLVRNPFGQVPALQD--GDLYLFESRAICKY 73 Query: 93 ---------LDEAYPGKKLLPD-------DPYEKACQKMILELFSKVPSLVGSFIRSQNK 136 L E + + D + Y A ++ ++ P L G+ + Sbjct: 74 AARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLIS-PMLGGTTDQKVVD 132 Query: 137 EDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHT 196 E+ E+ +K E LT K + G+ +S+ D L A +D Sbjct: 133 ENL----EKLKKVLEVYEARLT--KCKYLAGDFLSLADLNHVSVTLCLFATPYASVLDAY 186 Query: 197 PKLKLWMAAMKEDPTV 212 P +K W + + E P+V Sbjct: 187 PHVKAWWSGLMERPSV 202 >1JLV-A nrPDB Length = 209 Score = 34.7 bits (78), Expect = 0.042, Method: Compositional matrix adjust. Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 14/79 (17%) Query: 52 ININLKN-------KPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGK--KL 102 +N+ L N KPE F K NP +P L ++ G ++ES C YL E Y GK KL Sbjct: 26 LNLKLTNLMAGEHMKPE-FLKINPQHCIPTLVDN-GFALWESRAICTYLAEKY-GKDDKL 82 Query: 103 LPDDPYEKAC--QKMILEL 119 P DP ++A Q++ ++ Sbjct: 83 YPKDPQKRAVVNQRLYFDM 101 >3GX0-A nrPDB Length = 215 Score = 33.9 bits (76), Expect = 0.072, Method: Compositional matrix adjust. Identities = 44/207 (21%), Positives = 86/207 (41%), Gaps = 27/207 (13%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKN----KPEWFFKKNPFGLVPVL------ENSQGQ 81 P + L L+ + + +I ++L +PE F + +P +P + + + Sbjct: 9 TPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPE-FLRISPNNKIPAIVDHSPADGGEPL 67 Query: 82 LIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAG 141 ++ES YL E L + E+A + LF +V L G + + ++A Sbjct: 68 SLFESGAILLYLAEK--TGLFLSHETRERAA--TLQWLFWQVGGL-GPMLGQNHHFNHAA 122 Query: 142 LK------EEFRKEFTKLEEVLTNK--KTTFFGGNSISMIDYLIWPWFERLEAMKLNECV 193 + E ++ E +L VL + + + GG + S+ D WPW +++ + Sbjct: 123 PQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYSIADIACWPWVNAWTRQRIDLAM 182 Query: 194 DHTPKLKLWMAAMKEDP-TVSALLTSE 219 P +K W ++ P T ALL ++ Sbjct: 183 --YPAVKNWHERIRSRPATGQALLKAQ 207 >5F05-A nrPDB Length = 212 Score = 33.5 bits (75), Expect = 0.083, Method: Compositional matrix adjust. Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 ++++ +R L K + E++N+NL ++K E NPFG VP + Sbjct: 3 LKLHGSVLSTNTQRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDL 62 Query: 81 QLIYESAITCEYLDEAYPGK 100 +L +ES +Y+ Y K Sbjct: 63 KL-FESRAISQYVAHQYASK 81 >5Y7I-A nrPDB Length = 261 Score = 33.1 bits (74), Expect = 0.11, Method: Compositional matrix adjust. Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 9/177 (5%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 CPF +R +VL KG++ V ++++ KP P G P G L + E Sbjct: 46 CPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLAP-GTNPPFLLYNGTLKTDFIKIEE 104 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 +L++ + P K + ++F+K + + +N + ++ +EF Sbjct: 105 FLEQTLAPPRYPHLSPVNKESFDVGADIFAKFSAFI------KNSPNNPLQEKNLLREFK 158 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 +L++ L + NS+ I + + + + L +C + PKL + A K+ Sbjct: 159 RLDDYLNSPLPEEIDHNSVETITVSNRKFLDG-DRLTLADC-NLLPKLHVIRVAAKK 213 >2FIC-A nrPDB Length = 251 Score = 32.0 bits (71), Expect = 0.25, Method: Compositional matrix adjust. Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 6/80 (7%) Query: 84 YESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSL----VGSFIRSQNKEDY 139 YES T + DEA K +K ++M ++L ++PSL VG ++ + + Sbjct: 167 YESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNT--FQSI 224 Query: 140 AGLKEEFRKEFTKLEEVLTN 159 AGL+E F KE +KL + L + Sbjct: 225 AGLEENFHKEMSKLNQNLND 244 >5F0G-A nrPDB Length = 215 Score = 30.8 bits (68), Expect = 0.49, Method: Compositional matrix adjust. Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 7/76 (9%) Query: 59 KPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKK--LLPDDPYEKACQKMI 116 KPE F K NP +P L ++ G I+ES YL E Y GK LLP+DP ++A Sbjct: 40 KPE-FVKLNPQHTIPTLVDN-GFSIWESRAIAVYLVEKY-GKDDYLLPNDPKKRAVINQ- 95 Query: 117 LELFSKVPSLVGSFIR 132 L+ + +L SF + Sbjct: 96 -RLYFDMGTLYESFAK 110 >1FHE-A nrPDB Length = 217 Score = 30.8 bits (68), Expect = 0.58, Method: Compositional matrix adjust. Identities = 15/59 (25%), Positives = 36/59 (61%), Gaps = 5/59 (8%) Query: 164 FFGGNSISMIDYLIWPWFERLEAMKL--NECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 + G+S+S +D+++ +E L++++ C+D PKLK + + ++ P + A + S++ Sbjct: 141 YLTGSSVSHVDFML---YETLDSIRYLAPHCLDEFPKLKEFKSRIEALPKIKAYMESKR 196 >1XWK-A nrPDB Length = 218 Score = 30.8 bits (68), Expect = 0.59, Method: Compositional matrix adjust. Identities = 17/62 (27%), Positives = 35/62 (56%), Gaps = 5/62 (8%) Query: 161 KTTFFGGNSISMIDYLIWPWFERLEAMKLNE--CVDHTPKLKLWMAAMKEDPTVSALLTS 218 K +F GN I+ +D+L+ ++ L+ ++ E C+D P LK +++ + +SA + S Sbjct: 144 KRPWFAGNKITFVDFLV---YDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKS 200 Query: 219 EK 220 + Sbjct: 201 SR 202 >6GCB-A nrPDB Length = 325 Score = 30.0 bits (66), Expect = 0.84, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 5/87 (5%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQG 80 +G +Y CP+A RT +V K KG+ E++ + + + P + PFG V ++ Sbjct: 45 KGRYHLYVAYSCPWATRTLIVRKIKGLE-EIVGVTIVS-PLFSAHGWPFGDVSPFPGAEA 102 Query: 81 QLIYESAITCE-YL--DEAYPGKKLLP 104 Y + + YL D Y G+ +P Sbjct: 103 DPFYNAQYVRDLYLRADPKYEGRFTVP 129 >2KLX-A nrPDB Length = 89 Score = 30.0 bits (66), Expect = 0.84, Method: Compositional matrix adjust. Identities = 15/57 (26%), Positives = 27/57 (47%) Query: 17 GPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVP 73 GP I +Y+ CP+ +R R +L KG+++ I+ + + E + N P Sbjct: 1 GPGSMKEIILYTRPNCPYCKRARDLLDKKGVKYTDIDASTSLRQEMVQRANGRNTFP 57 >1TU7-A nrPDB Length = 208 Score = 30.0 bits (66), Expect = 0.94, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 7/68 (10%) Query: 149 EFTKLEEVLTNKKT--TFFGGNSISMIDYLIWPWFERLEAMKLNE--CVDHTPKLKLWMA 204 E K E++L + G+ IS DY + FE L+ ++ + C+D P LK++ Sbjct: 124 ELAKFEKLLATRGNGRNLILGDKISYADYAL---FEELDVHQILDPHCLDKFPLLKVFHQ 180 Query: 205 AMKEDPTV 212 MK+ P + Sbjct: 181 RMKDRPKL 188 >4K0G-A nrPDB Length = 251 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 23/43 (53%) Query: 33 PFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVL 75 PF++R +VL KG+ V ++ K + E K P G +P L Sbjct: 35 PFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFL 77 >1B4P-A nrPDB Length = 217 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 5/60 (8%) Query: 161 KTTFFGGNSISMIDYLIWPWFERLEAMKLNE--CVDHTPKLKLWMAAMKEDPTVSALLTS 218 K +F GN I+ +D+L+ ++ L+ ++ E C+D P LK ++A + +S + S Sbjct: 143 KQPWFAGNKITYVDFLV---YDVLDQHRIFEPKCLDAFPNLKDFVARFEGLKKISDYMKS 199 >4TR1-A nrPDB Length = 92 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 13/52 (25%), Positives = 29/52 (55%), Gaps = 1/52 (1%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP-EWFFKKNPFGLVP 73 +I IY+ +CP++++ +L +KG+ + +++ +K E K + VP Sbjct: 3 NITIYTKNYCPYSKKAVSLLSSKGVDFKEVDVTHDSKAFEDVMAKTGWDTVP 54 >3IR4-A nrPDB Length = 218 Score = 28.9 bits (63), Expect = 1.9, Method: Compositional matrix adjust. Identities = 19/84 (22%), Positives = 39/84 (46%), Gaps = 6/84 (7%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG--LVPVLENSQ 79 ++++Y CPF + R++ G+++ + +N+ + G +VP+L+ Sbjct: 2 NAMKLYIYDHCPFCVKARMIF---GLKNIPVELNVLQNDDEATPTRMIGQKMVPILQKDD 58 Query: 80 GQLIYESAITCEYLDEAYPGKKLL 103 + + ES Y+D GK LL Sbjct: 59 SRYLPESMDIVHYVDN-LDGKPLL 81 >3GTU-B nrPDB Length = 224 Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust. Identities = 22/102 (21%), Positives = 49/102 (48%), Gaps = 3/102 (2%) Query: 121 SKVPSLVGSFIRSQNKEDYAGLKEEFRKEF-TKLEEV-LTNKKTTFFGGNSISMIDYLIW 178 ++V IR D+ LK ++ +E +L++ + K ++F G ++ +D+L + Sbjct: 105 NQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTY 164 Query: 179 PWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 ++ +C+D P LK +M + ++A L S++ Sbjct: 165 DILDQNRIFD-PKCLDEFPNLKAFMCRFEALEKIAAYLQSDQ 205 >3GRX-A nrPDB Length = 82 Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust. Identities = 14/52 (26%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLK-NKPEWFFKKNPFGLVP 73 ++ IY+ CP++ R + +L +KG+ + + I+ K E K++ VP Sbjct: 2 NVEIYTKETCPYSHRAKALLSSKGVSFQELPIDGNAAKREEMIKRSGRTTVP 53 >2DC5-A nrPDB Length = 231 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 14/60 (23%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Query: 161 KTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 K +F G+ I+ +D++ + ER + + +C+D P LK ++A + +S + + + Sbjct: 151 KRPWFAGDKITFVDFIAYDVLERNQVFEA-KCLDAFPNLKDFIARFEGLKKISDYMKTSR 209 >3QMX-A nrPDB Length = 99 Score = 28.5 bits (62), Expect = 2.6, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 19/42 (45%) Query: 17 GPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKN 58 G I IY+ CPF R +LK KG+ + I+ N Sbjct: 11 GSAVSAKIEIYTWSTCPFCMRALALLKRKGVEFQEYCIDGDN 52 >5FWG-A nrPDB Length = 217 Score = 28.5 bits (62), Expect = 2.6, Method: Compositional matrix adjust. Identities = 14/60 (23%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Query: 161 KTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 K +F G+ ++ +D+L + ++ + +C+D P LK ++A + +SA + S + Sbjct: 143 KRPWFAGDKVTYVDFLAYDILDQYHIFE-PKCLDAFPNLKDFLARFEGLKKISAYMKSSR 201 >4G0L-A nrPDB Length = 328 Score = 28.1 bits (61), Expect = 3.1, Method: Compositional matrix adjust. Identities = 44/210 (20%), Positives = 78/210 (37%), Gaps = 42/210 (20%) Query: 25 RIYSMRFCPFAERTRLVLKAKGIRHEVININLKN----KPEWFFK------------KNP 68 +Y CP+A RT ++ K KG+ I++++ N + W F +N Sbjct: 56 HLYVSLACPWAHRTLIMRKLKGLE-PFISVSVVNPLMLENGWTFDDSFPGATGDTLYQNE 114 Query: 69 F---------------GLVPVLENSQGQLIY--ESAITCEYLDEAYPGKKLLPDDPYEKA 111 F VPVL + + I ESA + A+ D Y A Sbjct: 115 FLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPA 174 Query: 112 CQKMILELFSKVPSLVGSFIR----SQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGG 167 Q I EL + V + + + ++E Y + + +LE++L + + G Sbjct: 175 LQTKIDELNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQHR--YLTG 232 Query: 168 NSISMIDYLIWPWFERLEAMKLNE--CVDH 195 N ++ D +W R + + + C H Sbjct: 233 NQLTEADIRLWTTLVRFDPVYVTHFKCDKH 262 >3NH5-A nrPDB Length = 327 Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 13/54 (24%) Query: 64 FKKNPFGLVPVLENSQGQLIYESAITCEYLDE--------AYPGKKLLPDDPYE 109 ++ F +PVL N +A C YLD + G PDDPYE Sbjct: 50 LQRPSFSAMPVLANPAA-----TAACCRYLDRDLNRSCTLTFLGSTATPDDPYE 98 >1G7O-A nrPDB Length = 215 Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust. Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGI---RHEVININLKNKPEWFFKKNPFGLVPVLENSQG 80 +++Y CP+ + R++ K I H ++N + + +K VP+L+ Sbjct: 1 MKLYIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVGQKQ----VPILQKDDS 56 Query: 81 QLIYESAITCEYLDEAYPGKKLL 103 + + ES Y+D+ GK LL Sbjct: 57 RYMPESMDIVHYVDK-LDGKPLL 78 >1PN9-A nrPDB Length = 209 Score = 28.1 bits (61), Expect = 3.4, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 7/65 (10%) Query: 59 KPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGK--KLLPDDPYEKAC--QK 114 KPE F K NP +P L ++ G ++ES YL E Y GK KL P DP ++A Q+ Sbjct: 40 KPE-FLKLNPQHCIPTLVDN-GFALWESRAIQIYLAEKY-GKDDKLYPKDPQKRAVVNQR 96 Query: 115 MILEL 119 + ++ Sbjct: 97 LYFDM 101 >5LLW-B nrPDB Length = 685 Score = 27.7 bits (60), Expect = 5.1, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 17/29 (58%) Query: 68 PFGLVPVLENSQGQLIYESAITCEYLDEA 96 PFG + ++E Q++Y SA + EY A Sbjct: 32 PFGAMLIVEKDTQQIVYASANSAEYFSVA 60 >3FK2-A nrPDB Length = 246 Score = 27.7 bits (60), Expect = 5.1, Method: Compositional matrix adjust. Identities = 12/47 (25%), Positives = 22/47 (46%) Query: 188 KLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSP 234 K+N + W M+ D + LT+ + +Q +EL++Q P Sbjct: 194 KVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCP 240 >5LLY-D nrPDB Length = 529 Score = 27.3 bits (59), Expect = 5.5, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 17/29 (58%) Query: 68 PFGLVPVLENSQGQLIYESAITCEYLDEA 96 PFG + ++E Q++Y SA + EY A Sbjct: 32 PFGAMLIVEKDTQQIVYASANSAEYFSVA 60 >5IRC-A nrPDB Length = 201 Score = 26.9 bits (58), Expect = 7.3, Method: Compositional matrix adjust. Identities = 12/47 (25%), Positives = 22/47 (46%) Query: 188 KLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSP 234 K+N + W M+ D + LT+ + +Q +EL++Q P Sbjct: 149 KVNLMTSENLSICFWPTLMRPDFSSMDALTATRSYQTIIELFIQQCP 195 >6GC9-A nrPDB Length = 327 Score = 26.9 bits (58), Expect = 7.9, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININL 56 +G +Y CP+A RT +V K KG+ E I++++ Sbjct: 46 KGRYHLYVSYACPWATRTLIVRKIKGLE-EFIDVSV 80 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3LFL-A nrPDB 332 7e-92 3QAG-A nrPDB 287 3e-78 2VO4-A nrPDB 204 3e-53 5J5N-A nrPDB 204 3e-53 4CHS-A nrPDB 202 1e-52 3WD6-A nrPDB 201 2e-52 4J2F-A nrPDB 198 1e-51 5ECL-B nrPDB 196 6e-51 5G5A-A nrPDB 194 3e-50 3RBT-A nrPDB 189 7e-49 6EP7-A nrPDB 189 1e-48 4QQ7-A nrPDB 171 4e-43 2CZ2-A nrPDB 162 1e-40 4PQI-A nrPDB 159 9e-40 5ELG-A nrPDB 158 2e-39 1FW1-A nrPDB 157 4e-39 4AGS-A nrPDB 157 5e-39 5IQY-A nrPDB 156 8e-39 5D9W-A nrPDB 155 1e-38 1E6B-A nrPDB 154 5e-38 4PNG-A nrPDB 151 2e-37 3IBH-A nrPDB 151 2e-37 4YH2-A nrPDB 151 3e-37 1GWC-A nrPDB 150 7e-37 5LOL-A nrPDB 147 5e-36 3VWX-A nrPDB 147 5e-36 3PR8-A nrPDB 144 3e-35 5F07-A nrPDB 144 3e-35 1OYJ-A nrPDB 143 6e-35 3TOT-A nrPDB 141 2e-34 5N9U-A nrPDB 141 3e-34 3M8N-A nrPDB 141 3e-34 4IGJ-A nrPDB 141 3e-34 3M3M-A nrPDB 140 6e-34 4PXO-A nrPDB 139 1e-33 5A5K-A nrPDB 137 5e-33 2IL3-A nrPDB 136 8e-33 2PMT-A nrPDB 136 9e-33 4MK3-A nrPDB 136 9e-33 5NR1-A nrPDB 136 1e-32 3R2Q-A nrPDB 133 6e-32 4MDC-A nrPDB 131 2e-31 1AW9-A nrPDB 129 1e-30 3UAR-A nrPDB 127 3e-30 2GDR-A nrPDB 126 1e-29 2FHE-A nrPDB 125 2e-29 2JL4-A nrPDB 123 6e-29 1F2E-A nrPDB 122 1e-28 3NIV-A nrPDB 121 3e-28 3UBL-A nrPDB 119 1e-27 2D2Z-A nrPDB 114 3e-26 2PVQ-A nrPDB 112 1e-25 6JWK-A nrPDB 111 3e-25 4PTS-A nrPDB 106 8e-24 Sequences not found previously or not previously below threshold: 5F06-A nrPDB 126 6e-30 5EY6-A nrPDB 116 9e-27 4RI7-A nrPDB 111 2e-25 1AXD-A nrPDB 110 5e-25 6F05-A nrPDB 110 6e-25 3LG6-A nrPDB 109 9e-25 5F05-A nrPDB 109 9e-25 1JLV-A nrPDB 104 5e-23 1PN9-A nrPDB 100 6e-22 1N2A-A nrPDB 99 2e-21 3C8E-A nrPDB 99 2e-21 5ZWP-A nrPDB 97 4e-21 2WRT-A nrPDB 96 2e-20 3MAK-A nrPDB 94 5e-20 4IKH-A nrPDB 94 5e-20 5F0G-A nrPDB 93 8e-20 3GX0-A nrPDB 93 1e-19 1V2A-A nrPDB 92 2e-19 4MPF-A nrPDB 91 5e-19 5Y7I-A nrPDB 91 5e-19 3GH6-A nrPDB 90 9e-19 1VF1-A nrPDB 88 3e-18 3LSZ-A nrPDB 88 3e-18 1FHE-A nrPDB 87 6e-18 1G6W-A nrPDB 87 7e-18 4GTU-A nrPDB 86 2e-17 2R5G-A nrPDB 85 2e-17 1F3B-A nrPDB 85 3e-17 2DC5-A nrPDB 84 8e-17 4K0G-A nrPDB 83 9e-17 3M1G-A nrPDB 83 1e-16 3FY7-A nrPDB 82 2e-16 2VCT-A nrPDB 82 2e-16 1PL2-A nrPDB 82 2e-16 1HNA-A nrPDB 82 2e-16 2VCV-A nrPDB 82 2e-16 2C3Q-A nrPDB 81 4e-16 3I6A-A nrPDB 81 5e-16 5LCZ-A nrPDB 81 6e-16 1B48-A nrPDB 79 1e-15 1DUG-A nrPDB 79 2e-15 1B8X-A nrPDB 78 3e-15 1BG5-A nrPDB 78 3e-15 3GTU-B nrPDB 77 5e-15 1EV4-A nrPDB 77 5e-15 1XWK-A nrPDB 76 1e-14 1GUL-A nrPDB 76 2e-14 5D73-A nrPDB 76 2e-14 5FWG-A nrPDB 76 2e-14 1YQ1-A nrPDB 75 3e-14 4FQU-A nrPDB 74 4e-14 5AN1-A nrPDB 74 4e-14 1B4P-A nrPDB 73 9e-14 4Q5R-A nrPDB 73 9e-14 4Q5F-A nrPDB 73 1e-13 2AAW-A nrPDB 71 3e-13 1GSQ-A nrPDB 70 8e-13 4WR5-A nrPDB 70 1e-12 3PPU-A nrPDB 69 2e-12 2GLR-A nrPDB 68 3e-12 3BBY-A nrPDB 68 4e-12 1GSU-A nrPDB 67 5e-12 5F8B-A nrPDB 67 5e-12 4G0L-A nrPDB 67 7e-12 18GS-A nrPDB 66 2e-11 4Q5Q-A nrPDB 65 2e-11 1TU7-A nrPDB 64 6e-11 1ZL9-A nrPDB 64 8e-11 6GCB-A nrPDB 63 1e-10 4BVY-B nrPDB 63 1e-10 1U3I-A nrPDB 62 2e-10 3KXO-A nrPDB 62 2e-10 2WDU-A nrPDB 61 3e-10 5Y9Z-A nrPDB 61 5e-10 6GC9-A nrPDB 61 6e-10 2CA8-A nrPDB 61 6e-10 6GZF-A nrPDB 60 9e-10 4LMW-A nrPDB 60 1e-09 4USS-A nrPDB 60 1e-09 1G7O-A nrPDB 58 3e-09 3IR4-A nrPDB 57 5e-09 2YV7-A nrPDB 56 1e-08 2HNL-A nrPDB 54 8e-08 1M0U-A nrPDB 52 2e-07 5LKB-A nrPDB 49 2e-06 4LMV-A nrPDB 49 2e-06 2PBJ-A nrPDB 48 3e-06 5CAX-A nrPDB 44 8e-05 3GRX-A nrPDB 40 0.001 3QMX-A nrPDB 38 0.003 4LA1-A nrPDB 38 0.004 2X8H-A nrPDB 37 0.005 2KLX-A nrPDB 37 0.010 3NZN-A nrPDB 35 0.038 4TR1-A nrPDB 35 0.040 3IC4-A nrPDB 34 0.047 1Z7R-A nrPDB 32 0.26 1NM3-A nrPDB 32 0.26 5W1J-A nrPDB 31 0.37 4XRU-B nrPDB 31 0.51 1H75-A nrPDB 31 0.51 2LQQ-A nrPDB 31 0.57 1HX8-A nrPDB 30 0.77 2MZC-A nrPDB 30 0.91 4RK9-A nrPDB 30 0.92 3LGC-A nrPDB 30 1.2 3PFO-A nrPDB 29 1.4 3GNJ-A nrPDB 29 2.1 4FIW-A nrPDB 29 2.2 2DYB-A nrPDB 29 2.4 1R7H-A nrPDB 28 3.0 1H6H-A nrPDB 28 3.4 2LV3-A nrPDB 28 3.7 3UG7-A nrPDB 28 4.5 3MZS-A nrPDB 28 4.7 3N9Z-A nrPDB 28 4.8 4PFT-A nrPDB 27 5.7 >3LFL-A nrPDB Length = 240 Score = 332 bits (852), Expect = 7e-92, Method: Composition-based stats. Identities = 240/241 (99%), Positives = 240/241 (99%), Gaps = 1/241 (0%) Query: 1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP 60 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP Sbjct: 1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP 60 Query: 61 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF 120 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF Sbjct: 61 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF 120 Query: 121 SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW 180 SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLE VLTNKKTTFFGGNSISMIDYLIWPW Sbjct: 121 SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLE-VLTNKKTTFFGGNSISMIDYLIWPW 179 Query: 181 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG 240 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG Sbjct: 180 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG 239 Query: 241 L 241 L Sbjct: 240 L 240 >3QAG-A nrPDB Length = 239 Score = 287 bits (734), Expect = 3e-78, Method: Composition-based stats. Identities = 156/239 (65%), Positives = 189/239 (79%), Gaps = 1/239 (0%) Query: 1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP 60 MSG++ R+LGKGS PPGPVPEG IRIYSMRFCP++ RTRLVLKAK IRHEV+NINL+NKP Sbjct: 1 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP 60 Query: 61 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF 120 EW++ K+PFG +PVLE SQ QLIYES I CEYLD+AYPG+KL P DPYE+A QKM+LELF Sbjct: 61 EWYYTKHPFGHIPVLETSQSQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF 120 Query: 121 SKVPSLVGS-FIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP 179 SKVP L + ++ + LK R+EF+ LEE+L + TTFFGG SISMIDYL+WP Sbjct: 121 SKVPHLTKECLVALRSGRESTNLKAALRQEFSNLEEILEYQNTTFFGGTSISMIDYLLWP 180 Query: 180 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACD 238 WFERL+ + +CV HTP L+LW++AMK DPTVSALL + +QGFL LY QN+P A D Sbjct: 181 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVSALLMDKSIFQGFLNLYFQNNPNAFD 239 >2VO4-A nrPDB Length = 219 Score = 204 bits (519), Expect = 3e-53, Method: Composition-based stats. Identities = 58/215 (26%), Positives = 99/215 (46%), Gaps = 8/215 (3%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQG 80 + + PF R R+ L KGI++E +L+NK + NP +PVL ++ G Sbjct: 3 DEVVLLDFWPSPFGMRVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHN-G 61 Query: 81 QLIYESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDY 139 + I ES I +Y++E + + LLP DPY++A + + K +G I + E+ Sbjct: 62 KPICESLIAVQYIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEEK 121 Query: 140 AGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP---WFERLEAMKLNECVDHT 196 K+EF + LEE L +K T+FGG+++ +D + P WF+ E Sbjct: 122 EAAKKEFIEALKLLEEQLGDK--TYFGGDNLGFVDIALVPFYTWFKAYETFGTLNIESEC 179 Query: 197 PKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQ 231 PK W + +V+ L ++ F+ + Sbjct: 180 PKFIAWAKRCLQKESVAKSLPDQQKVYEFIMDLRK 214 >5J5N-A nrPDB Length = 231 Score = 204 bits (518), Expect = 3e-53, Method: Composition-based stats. Identities = 56/215 (26%), Positives = 96/215 (44%), Gaps = 8/215 (3%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGL-VPVLENSQG 80 + + PF R RL L KG+++E +L NK + NP +PVL ++ G Sbjct: 15 DQVTLLDFWPSPFGMRVRLALAEKGVKYEYSEEDLWNKSALLLQMNPVNKQIPVLVHN-G 73 Query: 81 QLIYESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDY 139 + + ES I +Y+DE + LLP DPY++A + + K +G I ++ E+ Sbjct: 74 KPVCESLIIVQYIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKKGEEQ 133 Query: 140 AGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP---WFERLEAMKLNECVDHT 196 K++F +E L +K +FGG +I +D + P WF E + Sbjct: 134 EAAKKDFIDSLKLMEGELGDK--PYFGGETIGYVDIALVPFYSWFYAYETIGNFNIEAEC 191 Query: 197 PKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQ 231 PK+ + + TVS L + F+ + ++ Sbjct: 192 PKMIAYCKRCLQKETVSKALEDPQKVYDFVLMLMK 226 >4CHS-A nrPDB Length = 219 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 57/216 (26%), Positives = 97/216 (44%), Gaps = 8/216 (3%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQ 79 + + PF R R+ L KGI +E +L+NK + NP +PVL ++ Sbjct: 2 TDEVVLLDFWPSPFGMRVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHN- 60 Query: 80 GQLIYESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKED 138 G+ I ES I +Y++E + + LLP DPY++A + + +G I + E+ Sbjct: 61 GKPISESLIAVQYIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSKGEE 120 Query: 139 YAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP---WFERLEAMKLNECVDH 195 K+EF + LEE L +K T+FGG++I +D + P WF+ E + Sbjct: 121 KEAAKKEFIEALKLLEEQLGDK--TYFGGDNIGFVDIALVPFYTWFKVYETFGSLNIENE 178 Query: 196 TPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQ 231 P+ W + +V+ L + F+ + Sbjct: 179 CPRFVAWAKRCLQKESVAKSLPDQHKVYEFVVEIRK 214 >3WD6-A nrPDB Length = 256 Score = 201 bits (511), Expect = 2e-52, Method: Composition-based stats. Identities = 88/231 (38%), Positives = 128/231 (55%), Gaps = 7/231 (3%) Query: 5 SARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFF 64 + + L KG P P G +R+Y+MR+CP+A+RT L L AK I +EV+NI+L +KPEW Sbjct: 13 NTKHLRKGD--PLPPFNGKLRVYNMRYCPYAQRTILALNAKQIDYEVVNIDLIDKPEWLT 70 Query: 65 KKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVP 124 K+ F VP +E ++ IYES +T EYLDE YP + LLP DP +KA K+I+E + + Sbjct: 71 TKSAFAKVPAIEIAEDVTIYESLVTVEYLDEVYPKRPLLPQDPLKKALDKIIVEASAPIQ 130 Query: 125 SLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERL 184 SL ++ + + + + K ++E L N+ T F G+ DY+IWPWFERL Sbjct: 131 SLFIKILKFSDTVNEEHV-AAYHKALDFIQEQLKNRGTVFLDGSEPGYADYMIWPWFERL 189 Query: 185 EAMKLNECVDHTPK----LKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQ 231 A +E V P L ++ M +D VS L + F E Y + Sbjct: 190 RAFAHDERVRLEPSKYSLLLEYIDNMLKDSAVSQYLIPLEILAKFHEAYTK 240 >4J2F-A nrPDB Length = 223 Score = 198 bits (504), Expect = 1e-51, Method: Composition-based stats. Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 7/214 (3%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGL-VPVLENSQGQL 82 ++++ PF+ R LK KGI +E + +L NK + NP +PVL + G+ Sbjct: 5 LKLHGAWPSPFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVLVHG-GKP 63 Query: 83 IYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGL 142 I ES I EYLDE +P LLP DP+E+A + ++ + + + R++ +E + Sbjct: 64 ICESTIILEYLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRTKGEELEKAV 123 Query: 143 KEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYL---IWPWFERLEAMKLNECVD--HTP 197 K T E + +FGG+ I ++D I W +E + + ++ P Sbjct: 124 KNCLEVLKTIEEHAMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIEEVAGVKVLESQKFP 183 Query: 198 KLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQ 231 +L W KE P + L F + + Sbjct: 184 RLHAWTENFKEAPIIKENLPDRDQMTAFFKRRRE 217 >5ECL-B nrPDB Length = 223 Score = 196 bits (499), Expect = 6e-51, Method: Composition-based stats. Identities = 55/213 (25%), Positives = 90/213 (42%), Gaps = 8/213 (3%) Query: 26 IYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQGQLIY 84 + F R R+ L+ KG+ E + NK + NP +PVL ++ G+ + Sbjct: 13 LLDYWPSMFGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLVHN-GKPVC 71 Query: 85 ESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLK 143 ES +Y+DEA+P K P DPY +A + + K + + + E+ K Sbjct: 72 ESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKGEEQEAGK 131 Query: 144 EEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIW---PWFERLEAMKLNECVDHTPKLK 200 +EF + LE L +K +FGG+S +D + WF+ E +PKL Sbjct: 132 KEFIEAVKILESELGDK--PYFGGDSFGYVDISLITFSSWFQAYEKFGNFSIESESPKLI 189 Query: 201 LWMAAMKEDPTVSALLTSEKDWQGFLELYLQNS 233 W E +VS L + + Y +N+ Sbjct: 190 AWAKRCMEKESVSKSLPDSEKIVAYAAEYRKNN 222 >5G5A-A nrPDB Length = 221 Score = 194 bits (493), Expect = 3e-50, Method: Composition-based stats. Identities = 59/215 (27%), Positives = 92/215 (42%), Gaps = 8/215 (3%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQG 80 + + F RTR+ L+ K ++ + +L NK + NP +PVL ++ G Sbjct: 3 DEVILLDFWPSMFGMRTRIALEEKNVKFDYREQDLWNKSPILLEMNPVHKKIPVLIHN-G 61 Query: 81 QLIYESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDY 139 + ES I EY+DE +P K LLP DPY++A K + K I E++ Sbjct: 62 NPVCESLIQIEYIDEVWPSKTPLLPSDPYQRAQAKFWGDFIDKKVYASARLIWGAKGEEH 121 Query: 140 AGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLI---WPWFERLEAMKLNECVDHT 196 K+EF + LE L +K T+FGG + +D + + WFE E Sbjct: 122 EAGKKEFIEILKTLESELGDK--TYFGGETFGYVDIALIGFYSWFEAYEKFGSFSIEAEC 179 Query: 197 PKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQ 231 PKL W E +V+ L + F+ + Sbjct: 180 PKLIAWGKRCVERESVAKSLPDSEKIIKFVPELRK 214 >3RBT-A nrPDB Length = 246 Score = 189 bits (481), Expect = 7e-49, Method: Composition-based stats. Identities = 79/248 (31%), Positives = 117/248 (47%), Gaps = 17/248 (6%) Query: 3 GESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEW 62 G S+ G PP P +R+Y + P+ R LVL+AK I++EV ++ PEW Sbjct: 7 GTYFHSVNAGVIPP-PALTDKLRLYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEW 65 Query: 63 FFKKNPFGLVPVLE--NSQG-QLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILEL 119 F KNP +PVLE QG + ++ES + C+YLDE Y L DPY KA ++++E Sbjct: 66 FRAKNPRLKIPVLEIPTDQGDRFLFESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIER 125 Query: 120 FSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP 179 F+++ ++A E+ + E+ LTN+ T +FGGN M+DY++WP Sbjct: 126 FNELIKGSLE----CFDTNFAFGSEQIIQTLEIFEKELTNRGTNYFGGNRPGMLDYMVWP 181 Query: 180 WFERLEAM------KLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNS 233 W ERL + K E P W M+ D V S Q + + Y Sbjct: 182 WVERLYLLRCVNDRKFVEKKSLFPNFADWGDQMQLDDIVKKHAHS---PQEYFDYYKNAR 238 Query: 234 PEACDYGL 241 + Y L Sbjct: 239 AHSMGYYL 246 >6EP7-A nrPDB Length = 220 Score = 189 bits (479), Expect = 1e-48, Method: Composition-based stats. Identities = 55/216 (25%), Positives = 93/216 (43%), Gaps = 8/216 (3%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLENSQ 79 E I + + RTR+ L+ K +++E +L NK + NP +PVL + Sbjct: 2 EEEIILLDYWASMYGMRTRIALEEKKVKYEYREEDLSNKSPLLLQMNPIHKKIPVLIHE- 60 Query: 80 GQLIYESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKED 138 G+ I ES I +Y+DE +P +LP DPY++A + + K + + S++ E Sbjct: 61 GKPICESIIQVQYIDELWPDTNPILPSDPYQRAQARFWADYIDKKTYVPCKALWSESGEK 120 Query: 139 YAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYL---IWPWFERLEAMKLNECVDH 195 K EF + L+ L +K +FGGN ++D + WF E + V Sbjct: 121 QEAAKIEFIEVLKTLDSELGDK--YYFGGNEFGLVDIAFIGFYSWFRTYEEVANLSIVLE 178 Query: 196 TPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQ 231 PKL W + +V+ L + + + Sbjct: 179 FPKLMAWAQRCLKRESVAKALPDSDKVLKSVSDHRK 214 >4QQ7-A nrPDB Length = 207 Score = 171 bits (432), Expect = 4e-43, Method: Composition-based stats. Identities = 64/208 (30%), Positives = 102/208 (49%), Gaps = 9/208 (4%) Query: 20 PEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQ 79 P + +YS CPF++R RLVL KG+ E+ +++L NKPE NP+G VP+L Sbjct: 2 PGSMMVLYSGTTCPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILVERD 61 Query: 80 GQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMIL-----ELFSKVPSLVGSFIRSQ 134 ++YES I EY+DE +P +L+P DP ++A ++ L ELF V +L ++ Sbjct: 62 L-ILYESNIINEYIDERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAA 120 Query: 135 NKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVD 194 ++++ + R T+L + K + G SM+D I P RL+ + + Sbjct: 121 -EKNHEKARLAIRDRLTQLAPIFV--KNKYMLGEEFSMLDVAIAPLLWRLDHYGIELSKN 177 Query: 195 HTPKLKLWMAAMKEDPTVSALLTSEKDW 222 P +K + AL SEK Sbjct: 178 AAPLMKYAERIFSRPAYIEALTPSEKVM 205 >2CZ2-A nrPDB Length = 223 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 9/187 (4%) Query: 12 GSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININL-----KNKPEWFFKK 66 GS+ + G +YS + R R+ L KGI +E++ INL + E F Sbjct: 1 GSSGSSGMQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTL 60 Query: 67 NPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSK--VP 124 NP VP L+ G I +S EYL+E P +LLP DP ++A +MI +L + P Sbjct: 61 NPMKQVPALKI-DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQP 119 Query: 125 SLVGSFIRSQNKEDYAGLKEEFR-KEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFER 183 S ++ +E+ ++ F LE++L + + G+ +SM D + P Sbjct: 120 LQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVAN 179 Query: 184 LEAMKLN 190 E K++ Sbjct: 180 AERFKVD 186 >4PQI-A nrPDB Length = 241 Score = 159 bits (402), Expect = 9e-40, Method: Composition-based stats. Identities = 68/248 (27%), Positives = 115/248 (46%), Gaps = 28/248 (11%) Query: 1 MSGESA--RSLGKGSAPP-------GPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEV 51 M+ SA +S+ + APP P+ +G+ ++Y+ CPFA+R + KG++ E+ Sbjct: 1 MATASALDKSVPEKLAPPLDATAEQPPLFDGTTKLYTCYTCPFAQRVWITRNFKGLQDEI 60 Query: 52 --ININLKNKPEWFFKK-NPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPY 108 + + L+N+P W+ +K P VP LE++ G++ ES +YL+ + G LLP DP Sbjct: 61 KLVPLILQNRPAWYPEKVYPPNKVPSLEHN-GKITGESLDLIKYLESNFEGPSLLPKDP- 118 Query: 109 EKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTN-KKTTFFGG 167 A ++ ELFS G+ + + L +E F LE L FF G Sbjct: 119 --AKKEFAEELFSYTDKFNGTVYTAFKGD----LAKEAGPAFDHLENALHKFDDGPFFLG 172 Query: 168 NSISMIDYLIWPWFERLEAMKLN----ECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQ 223 S++D P+ ERL L + KL W+ + + + A ++ D + Sbjct: 173 KEFSLVDIAYIPFVERLNIFLLEVFKYDITAGRQKLAAWIEEVNK---IEAYKQTKTDPK 229 Query: 224 GFLELYLQ 231 +E Y + Sbjct: 230 ELVEFYKK 237 >5ELG-A nrPDB Length = 221 Score = 158 bits (399), Expect = 2e-39, Method: Composition-based stats. Identities = 51/197 (25%), Positives = 85/197 (43%), Gaps = 15/197 (7%) Query: 28 SMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESA 87 + CPF++R L L+ K + +++ INL +KP+WF +P G VPVL+ + + +S Sbjct: 16 HLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD-KWVTDSD 74 Query: 88 ITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFR 147 + L+E YP L P E A S + G+F++S++ D G + Sbjct: 75 VIVGILEEKYPDPPL--KTPAEFASV------GSNIFGTFGTFLKSKDSND--GSEHALL 124 Query: 148 KEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLE----AMKLNECVDHTPKLKLWM 203 E LE L + F G +S +D + P L+ K + P + +M Sbjct: 125 VELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYM 184 Query: 204 AAMKEDPTVSALLTSEK 220 + + T EK Sbjct: 185 KTLFSLDSFEKTKTEEK 201 >1FW1-A nrPDB Length = 216 Score = 157 bits (397), Expect = 4e-39, Method: Composition-based stats. Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 11/193 (5%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININL-----KNKPEWFFKKNPFGLVPVLE 76 G +YS + R R+ L KGI ++ + INL + + F NP VP L+ Sbjct: 4 GKPILYSYFRSSCSWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLK 63 Query: 77 NSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSK--VPSLVGSFIRSQ 134 G I++S EYL+E P +LLP DP ++A +MI +L + P S ++ Sbjct: 64 I-DGITIHQSLAIIEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQV 122 Query: 135 NKEDY-AGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECV 193 +E + F LE++L + + G+ ++M D + P E K++ + Sbjct: 123 GEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVD--L 180 Query: 194 DHTPKLKLWMAAM 206 P + + Sbjct: 181 TPYPTISSINKRL 193 >4AGS-A nrPDB Length = 471 Score = 157 bits (396), Expect = 5e-39, Method: Composition-based stats. Identities = 59/232 (25%), Positives = 97/232 (41%), Gaps = 17/232 (7%) Query: 4 ESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWF 63 E+ R L SAP G + +YS FCPF +R RL + + + ++ + L +PEW+ Sbjct: 234 ENYRHLVPESAPMMGANGGHV-LYSNLFCPFVDRARLASELRKFQMHIVEVPLHPQPEWY 292 Query: 64 FKKNPFGLVPVLENSQGQLIYESAITCEYLD-EAYPGKKLLPDDPYEKACQKMILELFSK 122 NP VP L G+ ++ES + +Y+D A G L+P EK + Sbjct: 293 KYINPRDTVPALFTPSGEAVHESQLIVQYIDCVATKGSALVPRGDAEKEY--EVGFFVEN 350 Query: 123 VPSLVGSFIR--SQNKEDYAGLKEEFRKEFTKLEEVLTNK---KTTFFGGNSISMIDYLI 177 VG + + ED K E + +LE+ L + FFGG ++ D I Sbjct: 351 AGYFVGGLMSWIIRGGED---AKAELQWAAGELEQQLAKHPFGEGPFFGGKRMNAGDVAI 407 Query: 178 WPWFERLEAM-----KLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQG 224 P+ R +A + H P L A P ++ + ++++ Sbjct: 408 LPFLVRAKAFMPEFSGGYDLFAHFPLLNGLAEAGMATPEAKSVFRTLEEYKE 459 Score = 107 bits (266), Expect = 6e-24, Method: Composition-based stats. Identities = 40/223 (17%), Positives = 84/223 (37%), Gaps = 16/223 (7%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLK-NKPEWFFKKNPFGLVPVLENS--QG 80 +++Y CPF R +V + K + ++ + + L+ P+W+ + NP VP LE Sbjct: 27 LKLYVSATCPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPTLEVGNADK 86 Query: 81 QLIYESAITCEYLD-EAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDY 139 + ++ES + +YLD P L+ ++ + L +R Sbjct: 87 RFMFESMLIAQYLDNSGAPAGALMGSSAAQRHQIEFFLAQVGDFIGAAHGLLR---DPLS 143 Query: 140 AGLKEEFRKEFTKLEEVLTNKK--TTFFGGNSISMIDYLIWPWFERLE----AMKLNECV 193 ++ ++ +L + ++ +M D + P+ RL+ + Sbjct: 144 GEKRKAMDDNAAYVDGLLAANQTTGPYYCDGEFTMADVALVPFLVRLKPALMYYAGYDVF 203 Query: 194 DHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEA 236 P++K AA + +V + +E Y PE+ Sbjct: 204 CKAPRMKALWAAAAQRASVRETSPTAAQC---IENYRHLVPES 243 >5IQY-A nrPDB Length = 216 Score = 156 bits (394), Expect = 8e-39, Method: Composition-based stats. Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 15/193 (7%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 CPF++R L L+ K I +E+ ++L NKPEWF K +P G VPV + G+ I +S + + Sbjct: 23 CPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKVPVFNSGDGKWIADSDVITQ 82 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 ++E +P L+ P E A SK+ F++S++ D G ++ E Sbjct: 83 VIEEKFPTPSLV--TPPEYASV------GSKIFPSFVKFLKSKDASD--GSEKALLDELQ 132 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFER----LEAMKLNECVDHTPKLKLWMAAMK 207 L+E L + G ++S D + P LE K + ++ + + A+ Sbjct: 133 ALDEHL-KAHGPYISGENVSAADLSLGPKLFHLQVALEHFKGWKIPENLTSVHAYTKALF 191 Query: 208 EDPTVSALLTSEK 220 + + + Sbjct: 192 SRESFVKTKPANQ 204 >5D9W-A nrPDB Length = 230 Score = 155 bits (392), Expect = 1e-38, Method: Composition-based stats. Identities = 51/197 (25%), Positives = 88/197 (44%), Gaps = 15/197 (7%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 PF++R L L+ K + +E+ I+++NKP+WF K +P G VPV G+ I +S + + Sbjct: 37 SPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKVPVFNGGDGKWIPDSDVITQ 96 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 ++E YP L+ P E A SK+ S +F++S++ D G ++ E Sbjct: 97 VIEEKYPTPSLV--TPPEYASV------GSKIFSCFTTFLKSKDPND--GSEKALLTELQ 146 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFER----LEAMKLNECVDHTPKLKLWMAAMK 207 LEE L F G +IS D + P LE K + + + + A+ Sbjct: 147 ALEEHL-KAHGPFINGQNISAADLSLAPKLYHLQVALEHFKGWKIPEDLTNVHAYTEALF 205 Query: 208 EDPTVSALLTSEKDWQG 224 + +++ Sbjct: 206 SRESFIKTKAAKEHLIA 222 >1E6B-A nrPDB Length = 221 Score = 154 bits (388), Expect = 5e-38, Method: Composition-based stats. Identities = 57/226 (25%), Positives = 89/226 (39%), Gaps = 25/226 (11%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPE---WFFKKNPFGLVPVLEN 77 E +++YS A R R+ L KG+ +E I +NL + F K NP G VP L + Sbjct: 6 EEKLKLYSYWRSSCAHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVD 65 Query: 78 SQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF--SKVPSLVGSFIR--- 132 +I +S YLDE YP LLP D +++A + + P + IR Sbjct: 66 GD-VVINDSFAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIE 124 Query: 133 --SQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLN 190 +E A + K FT LE++L N G+ I + D + P Sbjct: 125 EKINVEEKTAWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHGA------ 178 Query: 191 ECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEA 236 + + M+ PT++ S + F + P+A Sbjct: 179 --------INRFQINMEPYPTLAKCYESYNELPAFQNALPEKQPDA 216 >4PNG-A nrPDB Length = 229 Score = 151 bits (382), Expect = 2e-37, Method: Composition-based stats. Identities = 51/220 (23%), Positives = 87/220 (39%), Gaps = 19/220 (8%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLENSQ 79 + +Y + P +L L A + +E + +N + K E F KKNP VP LE Sbjct: 9 KLILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLE-DD 67 Query: 80 GQLIYESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKED 138 G I++S YL Y L P D ++A L S V + + +RS K Sbjct: 68 GHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGV--IFANALRSITKPL 125 Query: 139 YAGL--------KEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLN 190 +AG + + + LE+ L + GN +++ D+ I LE Sbjct: 126 FAGKQTMIPKERYDAIIEVYDFLEKFLAGND--YVAGNQLTIADFSIISTVSSLEVFVKV 183 Query: 191 ECVDHTPKLKLWMAAMKEDPTV-SALLTSEKDWQGFLELY 229 + P++ W +++ P A + ++ F+ Y Sbjct: 184 DTTK-YPRIAAWFKRLQKLPYYEEANGNGARTFESFIREY 222 >3IBH-A nrPDB Length = 233 Score = 151 bits (382), Expect = 2e-37, Method: Composition-based stats. Identities = 54/213 (25%), Positives = 80/213 (37%), Gaps = 21/213 (9%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGI--RHEVININLK---NKPEWFFKKNPFGLVPVLEN 77 + IY P+ R R+ L K + + + INL +K F KN G VPVLE Sbjct: 18 KMIIYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLEL 77 Query: 78 SQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMI-------------LELFSKVP 124 G LI E EY+D L P EK M+ + P Sbjct: 78 DDGTLIAECTAITEYIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATP 137 Query: 125 SLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERL 184 L QNKE +++ + VL ++ + G+S SM D + Sbjct: 138 GLGPEVELYQNKEWGLRQRDKALHGMHYFDTVL--RERPYVAGDSFSMADITVIAGLIFA 195 Query: 185 EAMKLNECVDHTPKLKLWMAAMKEDPTVSALLT 217 +KL + + L+ W M++ P+V LL Sbjct: 196 AIVKL-QVPEECEALRAWYKRMQQRPSVKKLLE 227 >4YH2-A nrPDB Length = 222 Score = 151 bits (380), Expect = 3e-37, Method: Composition-based stats. Identities = 46/205 (22%), Positives = 82/205 (40%), Gaps = 18/205 (8%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLENSQ 79 + +Y + P +L L A + +E +N+++ + + +KNP VP LE Sbjct: 3 KLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLE-DD 61 Query: 80 GQLIYESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKED 138 G I++S YL Y L P DP ++A L S V G IRS +K Sbjct: 62 GHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANG--IRSISKSV 119 Query: 139 YAGLKEEFRKE--------FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLN 190 + + KE + +E L + + GN +++ D+ + LEA Sbjct: 120 LFQGQTKVPKERYDAIIEIYDFVETFLKGQD--YIAGNQLTIADFSLVSSVASLEAFVAL 177 Query: 191 ECVDHTPKLKLWMAAMKEDPTVSAL 215 + P++ W+ +++ P Sbjct: 178 DTTK-YPRIGAWIKKLEQLPYYEEA 201 >1GWC-A nrPDB Length = 230 Score = 150 bits (378), Expect = 7e-37, Method: Composition-based stats. Identities = 58/216 (26%), Positives = 97/216 (44%), Gaps = 12/216 (5%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGL-VPVLENSQ 79 +++ PF R +L L KG+ +E + +L K E K NP +PVL ++ Sbjct: 4 GDDLKLLGAWPSPFVTRVKLALALKGLSYEDVEEDLYKKSELLLKSNPVHKKIPVLIHN- 62 Query: 80 GQLIYESAITCEYLDEAY--PGKKLLPDDPYEKACQKMILELF-SKVPSLVGSFIRSQNK 136 G + ES I +Y+DE + G LLP DPYE+A + + K+ + ++R + + Sbjct: 63 GAPVCESMIILQYIDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKTE 122 Query: 137 EDYAGLKEEFRKEFTKLEEVL--TNKKTTFFGGNSISMIDYLI---WPWFERLEAMKLNE 191 E+ + K++ LE L +K FFGG+ + ++D + W + EA+ ++ Sbjct: 123 EEKSEGKKQAFAAVGVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSWMKVTEALSGDK 182 Query: 192 CVDH--TPKLKLWMAAMKEDPTVSALLTSEKDWQGF 225 D TP L W+ E A L F Sbjct: 183 IFDAAKTPLLAAWVERFIELDAAKAALPDVGRLLEF 218 >5LOL-A nrPDB Length = 215 Score = 147 bits (370), Expect = 5e-36, Method: Composition-based stats. Identities = 47/197 (23%), Positives = 83/197 (42%), Gaps = 15/197 (7%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 CPF++R L L+ K + ++ IN+ +KP+WF +P G VPV++ G+ + +S + Sbjct: 22 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIVG 80 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 L+E YP L P E A SK+ +F++S++ D G ++ E Sbjct: 81 LLEEKYPEPSL--KTPPEFASV------GSKIFGAFVTFLKSKDAND--GSEKALVDELE 130 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLE----AMKLNECVDHTPKLKLWMAAMK 207 LE L F G I+ +D + P LE K + ++ + A+ Sbjct: 131 ALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALF 190 Query: 208 EDPTVSALLTSEKDWQG 224 + ++ Sbjct: 191 SRESFENTKAKKEIVVA 207 >3VWX-A nrPDB Length = 222 Score = 147 bits (370), Expect = 5e-36, Method: Composition-based stats. Identities = 50/200 (25%), Positives = 79/200 (39%), Gaps = 16/200 (8%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLENS 78 G + +Y + P L LKA + E +NL K E + KKNP VP LE Sbjct: 2 GKLVLYGIDPSPPVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLE-E 60 Query: 79 QGQLIYESAITCEYLDEAY-PGKKLLPDDPYEKACQKMILELFSKVPSLVG-------SF 130 G LI++S YL Y L P D ++A + + V G F Sbjct: 61 DGHLIWDSHAIMAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLF 120 Query: 131 IRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLN 190 R+Q + + + + + LE L K + G+ +++ D+ I L A Sbjct: 121 FRNQTQIPQHQI-DSIVESYGFLESFL--KNNKYMAGDHLTIADFSIVTSVTSLVAFAEI 177 Query: 191 ECVDHTPKLKLWMAAMKEDP 210 + PKL W+ +++ P Sbjct: 178 DQ-SKFPKLSAWLKSLQSLP 196 >3PR8-A nrPDB Length = 229 Score = 144 bits (364), Expect = 3e-35, Method: Composition-based stats. Identities = 46/226 (20%), Positives = 90/226 (39%), Gaps = 16/226 (7%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL 82 S+++Y + +L L KG+ E + P+ + +P G VPVLE G Sbjct: 2 SLKLYGFSVSNYYNMVKLALLEKGLTFEEVTFYGGQAPQA-LEVSPRGKVPVLETEHG-F 59 Query: 83 IYESAITCEYLDEAYPGKKLLPDDPYEKACQKMIL-------ELFSKVPSLVGSFIRSQN 135 + E+++ +Y+++ GK LLP DP+ +A + +L EL ++ F S Sbjct: 60 LSETSVILDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPARTCYAESFFGMSVE 119 Query: 136 KEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMK----LNE 191 + + F L+ + + G +++ D + + A+ + Sbjct: 120 PLIKEKARADLLAGFATLKR--NGRFAPYVAGEQLTLADLMFCFSVDLANAVGKKVLNID 177 Query: 192 CVDHTPKLKLWMAAMKEDPTVSALLTS-EKDWQGFLELYLQNSPEA 236 + P+ K + M E+P + +L E F+E+ E Sbjct: 178 FLADFPQAKALLQLMGENPHMPRILADKEASMPAFMEMIRSGKREG 223 >5F07-A nrPDB Length = 213 Score = 144 bits (363), Expect = 3e-35, Method: Composition-based stats. Identities = 49/209 (23%), Positives = 82/209 (39%), Gaps = 16/209 (7%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPE---WFFKKNPFGLVPVLENSQG 80 +++Y +R L KG+ ++++++L + + F K PFG VPV+E+ Sbjct: 2 VKVYGPAVAVCPQRVMACLLEKGVEFDLVHVDLDSGEQKLPEFLLKQPFGQVPVVEDGDF 61 Query: 81 QLIYESAITCEYLDEAYP--GKKLLPDDPYEKACQKMILEL----FSKVPSLVGSFIRSQ 134 + ++ES Y Y G LL + EKA LE+ F+ + + + Sbjct: 62 K-LFESRAIIRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVVIL 120 Query: 135 NKEDYAGLKEEFRKEFTKLEEVLTN-----KKTTFFGGNSISMIDYLIWPWFERL-EAMK 188 + G E R KLE+VL K+ + G+S ++ D P L Sbjct: 121 PRIGQQGDSELVRTYEEKLEKVLDVYEKRLSKSKYLAGDSFTLADLSHLPATRYLVNEAG 180 Query: 189 LNECVDHTPKLKLWMAAMKEDPTVSALLT 217 L V KL W + P L+ Sbjct: 181 LGHLVKDRKKLNAWWEDISSRPAWKKLMN 209 >1OYJ-A nrPDB Length = 231 Score = 143 bits (361), Expect = 6e-35, Method: Composition-based stats. Identities = 52/221 (23%), Positives = 87/221 (39%), Gaps = 14/221 (6%) Query: 19 VPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-LVPVLEN 77 E + + PF +R R+ + KG+ E +L NK + + NP +PVL + Sbjct: 2 AEEKELVLLDFWVSPFGQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVHRKIPVLLH 61 Query: 78 SQGQLIYESAITCEYLDEAYPG-KKLLPD-------DPYEKACQKMILELFSKVPSLVGS 129 + G+ + ES + +YLD+A+PG LLP Y +A + + + GS Sbjct: 62 A-GRPVSESLVILQYLDDAFPGTPHLLPPANSGDADAAYARATARFWADYVDRKLYDCGS 120 Query: 130 FIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKK-TTFFGGNSISMIDYLIWP---WFERLE 185 + E A E + LE L +++ GG + +D + P WF E Sbjct: 121 RLWRLKGEPQAAAGREMAEILRTLEAELGDREFFGGGGGGRLGFVDVALVPFTAWFYSYE 180 Query: 186 AMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFL 226 + P+L W +V L S + F+ Sbjct: 181 RCGGFSVEEVAPRLAAWARRCGRIDSVVKHLPSPEKVYDFV 221 >3TOT-A nrPDB Length = 226 Score = 141 bits (356), Expect = 2e-34, Method: Composition-based stats. Identities = 38/215 (17%), Positives = 82/215 (38%), Gaps = 13/215 (6%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLI 83 +++ P+ + R+VL K I ++ + ++ N + NP G VP L G + Sbjct: 3 MKLIGSHASPYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQFNPLGKVPCLVMDDGGAL 62 Query: 84 YESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAG-L 142 ++S + EY D P +L+P E+ + L + + Q + Sbjct: 63 FDSRVIAEYADTLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTPEQRS 122 Query: 143 KEEFRKEFTKLEEVLTN-----KKTTFFGGNSISMIDYLIWPWFERLE-AMKLNECVDHT 196 + ++ K++E L T+ GN +++ D + L+ + + Sbjct: 123 ESWITRQHHKIDEALKAMSRGLADRTWCNGNHLTLADIAVGCALAYLDFRQPQVDWREQH 182 Query: 197 PKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQ 231 L + +++ P+ L ++ + LY Q Sbjct: 183 ANLAAFYTRIEKRPS---FLETQPQAE---NLYFQ 211 >5N9U-A nrPDB Length = 218 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 47/193 (24%), Positives = 82/193 (42%), Gaps = 16/193 (8%) Query: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 CPF +R L L+ K I ++ INL +KP+WF + +P G VPV++ + + +S + Sbjct: 20 CPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKVPVVKIDD-KWVADSDVIVG 78 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 L+E P L P E A SK+ F++S++ D G ++ +E Sbjct: 79 ILEEKNPEPPL--ATPPEFASV------GSKIFPSFVKFLKSKDPND--GTEQALLEELK 128 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLE----AMKLNECVDHTPKLKLWMAAMK 207 L+ L F G I+ +D + P LE K D+ + ++ + Sbjct: 129 ALDGHLKVH-GPFIAGEKITAVDLSLAPKLYHLEVALGHFKNWPIPDNLTHVLNYIKLLF 187 Query: 208 EDPTVSALLTSEK 220 + +E+ Sbjct: 188 SRESFKKTRAAEE 200 >3M8N-A nrPDB Length = 225 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 38/198 (19%), Positives = 84/198 (42%), Gaps = 16/198 (8%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 ++YSM+ + + RL L + + +++ +++ F KNP G VP+LE + G Sbjct: 4 YKLYSMQRSGNSYKVRLALALLDAPYRAVEVDILRGESRTPDFLAKNPSGQVPLLETAPG 63 Query: 81 QLIYESAITCEYLDEAYPGKKLLPDDPYEKAC--QKMILELFSKVPSLVGSFIRSQ---- 134 + + ES YL G L PD ++A Q M E + P++ ++ Sbjct: 64 RYLAESNAILWYLA---VGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKG 120 Query: 135 -NKEDYAGLKEEFRKEFTKLEEVLTNKKT-TFFGGNSISMIDYLIWPWFERLEAMKLNEC 192 L++ + + L+ + + KT +F +++ D ++ + + + Sbjct: 121 GRDLQTHALEDWLERGYAALQVMENHLKTNDYFAAGQLTIADIALYGYTHVADQCDFD-- 178 Query: 193 VDHTPKLKLWMAAMKEDP 210 + P + W+ +++ P Sbjct: 179 LSTFPAVNAWLRRVEQTP 196 >4IGJ-A nrPDB Length = 242 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 46/210 (21%), Positives = 86/210 (40%), Gaps = 14/210 (6%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEW---FFKKNPFGLVPVLE--- 76 ++R+YS A R RL L KG+ +E ++L + ++ +NP VPVLE Sbjct: 24 TLRLYSYWRSSSAWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEE 83 Query: 77 NSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILE-LFSKVPSLVGSFIRSQN 135 + + L+ +S E+L+E +P LLP D + +A + + E + S + + + Sbjct: 84 DGRTHLLVQSMAILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRML 143 Query: 136 KEDYAGLKEE-----FRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLN 190 +E G E + LE + + F G++ ++ D + P L+ Sbjct: 144 REKVPGWDREWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRFGLD 203 Query: 191 ECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 ++ P L+ A A + Sbjct: 204 --LEPYPTLRRVDEACAALAPFQAAHPDRQ 231 >3M3M-A nrPDB Length = 210 Score = 140 bits (352), Expect = 6e-34, Method: Composition-based stats. Identities = 42/206 (20%), Positives = 85/206 (41%), Gaps = 19/206 (9%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 ++Y + +L+L G+ +E +++ + E F KNP G +PVLE G Sbjct: 4 YKVYGDYRSGNCYKIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLELEDG 63 Query: 81 QLIYESAITCEYLDEAYPGKKLLPDDPYEK--ACQKMILELFSKVPSLVGSF-------I 131 ++ES +L + G + LP +P + Q E +S P + + + Sbjct: 64 TCLWESNAILNFLAD---GSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYEGL 120 Query: 132 RSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNE 191 + +E+Y L + K +E+ L+ T + G S+ D ++ + + + Sbjct: 121 PEERREEYLKLHKRGYKALDVMEKQLSR--TPYLVGEHYSIADIALYAYTHVADEGGFD- 177 Query: 192 CVDHTPKLKLWMAAMKEDPTVSALLT 217 + P ++ WM ++ P +L Sbjct: 178 -LSRYPGIQAWMQRVQSHPRHVPMLD 202 >4PXO-A nrPDB Length = 238 Score = 139 bits (350), Expect = 1e-33, Method: Composition-based stats. Identities = 46/212 (21%), Positives = 84/212 (39%), Gaps = 16/212 (7%) Query: 20 PEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLE 76 + +++Y A R R+ L KGI +E + ++L F NP G VP L Sbjct: 20 FQSMVKMYGNWRSAAAFRVRIALNLKGIAYEEVFLDLDAGDQHKPDFLAINPQGAVPALF 79 Query: 77 NSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFS-KVPSLVGSFIRSQN 135 + G + +S +YL+E G LLP++P +A + + ++ + L +R+ Sbjct: 80 DGDGPPLTQSLAILDYLEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFL 139 Query: 136 KEDY--------AGLKEEFRKEFTKLEEVLTNKKTT--FFGGNSISMIDYLIWPWFERLE 185 E+Y L+ F LE L+N+ T F G+++S D + + Sbjct: 140 MENYGLPRERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISLWVGTG 199 Query: 186 AMKLNECVDHTPKLKLWMAAMKEDPTVSALLT 217 ++ P +K + V+ Sbjct: 200 IFGID--TAAYPTVKRISEEVLALDAVARAHP 229 >5A5K-A nrPDB Length = 212 Score = 137 bits (344), Expect = 5e-33, Method: Composition-based stats. Identities = 43/210 (20%), Positives = 82/210 (39%), Gaps = 18/210 (8%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKN---KPEWFFKKNPFGLVPVLENS 78 I+++ R + L K + E++++ LK+ K E F +NPFG VP E+ Sbjct: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 Query: 79 QGQLIYESAITCEYLDEAYP--GKKLLPDDPY---EKACQKMILELFSKVPS-LVGSFIR 132 + ++ES +Y+ Y G LL D + A + +++ + Sbjct: 62 DLK-LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 Query: 133 SQNKEDYAGLKEE---FRKEFTKLEEVLTN-----KKTTFFGGNSISMIDYLIWPWFERL 184 Q + GL + +E KL +VL K+ + G + ++ D P + L Sbjct: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 Query: 185 EAMKLNECVDHTPKLKLWMAAMKEDPTVSA 214 + P++ W+A + + P Sbjct: 181 LGTPTKKLFTERPRVNEWVAEITKRPASEK 210 >2IL3-A nrPDB Length = 221 Score = 136 bits (343), Expect = 8e-33, Method: Composition-based stats. Identities = 51/206 (24%), Positives = 79/206 (38%), Gaps = 20/206 (9%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLENS 78 ++ +Y++ P L KA G+ E INL F K NP +PVL + Sbjct: 2 SNLVLYTLHLSPPCRAVELTAKALGLELEQKTINLLTGDHLKPEFVKLNPQHTIPVL-DD 60 Query: 79 QGQLIYESAITCEYLDEAY-PGKKLLPDDPYEKACQKMILELFSKVPSLVGSFI------ 131 G +I ES YL Y L P DP ++A L S V FI Sbjct: 61 NGTIITESHAIMIYLVTKYGKDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILF 120 Query: 132 --RSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKL 189 +S ED E +K + LE+ L + F G ++++ D+ + + Sbjct: 121 FGKSDIPEDRV---EYVQKSYELLEDTLVD---DFVAGPTMTIADFSCISTISSIMGVVP 174 Query: 190 NECVDHTPKLKLWMAAMKEDPTVSAL 215 E H P++ W+ +K+ P Sbjct: 175 LEQSKH-PRIYAWIDRLKQLPYYEEA 199 >2PMT-A nrPDB Length = 203 Score = 136 bits (342), Expect = 9e-33, Method: Composition-based stats. Identities = 46/212 (21%), Positives = 90/212 (42%), Gaps = 20/212 (9%) Query: 24 IRIY----SMRFCPFAERTRLVLKAKGIRHEVININLKNKP----EWFFKKNPFGLVPVL 75 +++Y S P +VL+ G+ + I+L+ K + F NP G VPVL Sbjct: 1 MKLYYTPGSCSLSP-----HIVLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVL 55 Query: 76 ENSQGQLIYESAITCEYLDEAYPGKKLL-PDDPYEKACQKMILELF-SKVPSLVGSFIRS 133 + G ++ E +YL + P + L+ P E+ Q L S+V S Sbjct: 56 QLDNGDILTEGVAIVQYLADLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPLFSS 115 Query: 134 QNKEDY-AGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNEC 192 E Y +K + + +F + +VL+ +K G+ ++ D ++ + + L+ Sbjct: 116 DTPESYLPVVKNKLKSKFVYINDVLSKQKC--VCGDHFTVADAYLFTLSQWAPHVALD-- 171 Query: 193 VDHTPKLKLWMAAMKEDPTVSALLTSEKDWQG 224 + L+ ++A + + P V + L +E + Sbjct: 172 LTDLSHLQDYLARIAQRPNVHSALVTEGLIKE 203 >4MK3-A nrPDB Length = 226 Score = 136 bits (342), Expect = 9e-33, Method: Composition-based stats. Identities = 38/197 (19%), Positives = 83/197 (42%), Gaps = 9/197 (4%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL 82 S+++Y+ + P+A + R+VL K I +E+I N+ + + NP G VP L G Sbjct: 22 SMKLYASQTSPYARKVRVVLAEKKIDYEMIEENVWSPDTTIGRFNPLGKVPCLVMEDGGA 81 Query: 83 IYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSF-IRSQNKEDYAG 141 +++S + EY D P +L+P E+ + L + + +++ Sbjct: 82 VFDSRVIAEYADTLSPVSRLIPQGSRERLEVRCWEALADGLLDAALLARLEVTQRKESER 141 Query: 142 LKEEFRKEFTKLEEVLTN-----KKTTFFGGNSISMIDYLIWPWFERLEAMKLNECV--D 194 + +++ +K++ LT T+ G ++ D + L+ + + D Sbjct: 142 SESWVQRQRSKIDAALTAMSTGLADKTWCTGTHYTLADVAVGCALAYLD-FRFPDIAWRD 200 Query: 195 HTPKLKLWMAAMKEDPT 211 P L + +++ + Sbjct: 201 RHPNLVAFQEKIEKRQS 217 >5NR1-A nrPDB Length = 228 Score = 136 bits (342), Expect = 1e-32, Method: Composition-based stats. Identities = 41/210 (19%), Positives = 76/210 (36%), Gaps = 19/210 (9%) Query: 26 IYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQ---L 82 ++ P + + RL L K + + + P F NP G+ PVL ++ Q + Sbjct: 7 LHHFPLDPASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMPPVLVETKHQRNLV 66 Query: 83 IYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSL-VGSFIRSQNKEDYA- 140 I E+ E+++E LL DP E+A + +L+ F + V F+ + E Sbjct: 67 ICETRAILEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGFLLHEKMEKRLL 126 Query: 141 -----------GLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKL 189 +E R +E +L + + G +S+ D+ ++ Sbjct: 127 RMGAPDLAALRQGREALRMHLGYIESLLQTRD--WLAGRRMSLADFAAAAHLSVIDYFG- 183 Query: 190 NECVDHTPKLKLWMAAMKEDPTVSALLTSE 219 + K W +K P +L Sbjct: 184 DVPWKDFQAAKTWYMKLKSRPCFRPILADR 213 >3R2Q-A nrPDB Length = 202 Score = 133 bits (335), Expect = 6e-32, Method: Composition-based stats. Identities = 42/203 (20%), Positives = 77/203 (37%), Gaps = 7/203 (3%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLI 83 +++ PF + ++L KGI E IN N + NP G VPVL +G+ Sbjct: 1 MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECW 60 Query: 84 YESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLK 143 ++S I EY++ +LP DP E + I L + +R Q + + Sbjct: 61 FDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSE 120 Query: 144 EEFRKEFTKLEEVLTNKKTTFFGG----NSISMIDYLIWPWFERLE--AMKLNECVDHTP 197 +E ++ K+ L + G +++++ I L + CVD P Sbjct: 121 DELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIACAVGYLNFRRVAPGWCVD-RP 179 Query: 198 KLKLWMAAMKEDPTVSALLTSEK 220 L + + + + + Sbjct: 180 HLVKLVENLFSRESFARTEPPKA 202 >4MDC-A nrPDB Length = 252 Score = 131 bits (330), Expect = 2e-31, Method: Composition-based stats. Identities = 44/221 (19%), Positives = 75/221 (33%), Gaps = 24/221 (10%) Query: 20 PEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQ 79 + +Y P + RL+L G + E+ F NP G +PV + Sbjct: 20 FQSMPTLYHHPMSPASRFVRLILSEYGYQTELSEEQPWENRRDFLTLNPAGTLPVYVDDS 79 Query: 80 GQLIYESAITCEYLDEAY----PGKKLLPDDPYEKACQKMILELFSKV-------PSLVG 128 + + + I EYLDE ++LL +DP+++A + + E F + P + Sbjct: 80 MRALCGATIISEYLDETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLVRE 139 Query: 129 SFIRSQNKEDYAG----------LKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIW 178 + Q D G + R+ L + G+ IS D Sbjct: 140 RIFKLQMTPDQGGGAPDSKILRTSRSNIRQHMKYL--SWLAGSRPWLAGDRISYGDLAAA 197 Query: 179 PWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSE 219 L+ + + P K W +K P+ LL Sbjct: 198 AAISVLDYLGEIDW-SDAPTAKEWYQRLKSRPSFRPLLAER 237 >1AW9-A nrPDB Length = 216 Score = 129 bits (324), Expect = 1e-30, Method: Composition-based stats. Identities = 43/204 (21%), Positives = 75/204 (36%), Gaps = 14/204 (6%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 +++Y M P R VL KG+ E++ ++L +K F NPFG +P L + Sbjct: 3 LKLYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDGD- 61 Query: 81 QLIYESAITCEYLDEAY--PGKKLLPDD-PYEKACQKMILELFSKVPSLVGSFIRSQNKE 137 ++++ES Y+ Y G LLP K + +E P+ + + Sbjct: 62 EVLFESRAINRYIASKYASEGTDLLPATASAAKLEVWLEVESHHFYPNASPLVFQLLVRP 121 Query: 138 DYAGLKEE--FRKEFTKLEEVLTN-----KKTTFFGGNSISMIDYLIWPWFERLEAMKLN 190 G + K +L +VL + + G+ ++ D + L Sbjct: 122 LLGGAPDAAVVDKHAEQLAKVLDVYEAHLARNKYLAGDEFTLADANHASYLLYLSKTPKA 181 Query: 191 ECVDHTPKLKLWMAAMKEDPTVSA 214 V P +K W A+ P Sbjct: 182 GLVAARPHVKAWWEAIVARPAFQK 205 >3UAR-A nrPDB Length = 227 Score = 127 bits (320), Expect = 3e-30, Method: Composition-based stats. Identities = 47/216 (21%), Positives = 89/216 (41%), Gaps = 14/216 (6%) Query: 24 IRIYSMR-FCPFAERTRLVLKAKGIRHEVININLKNKPE----WFFKKNPFGLVPVLENS 78 +++Y C A +VL+ G+ E+ N++L K F + NP G VP L+ Sbjct: 3 MKLYYFPGACSLAP--HIVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQLD 60 Query: 79 QGQLIYESAITCEYLDEAYPGKKLLPDDP-YEKACQKMILELFS-KVPSLVGSFIRSQNK 136 GQ++ E + +YL + P L+P +E+ L S ++ G F ++ Sbjct: 61 DGQVLTEDQVILQYLADLKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFGPFWNPESP 120 Query: 137 EDYAGLKEEFR-KEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDH 195 E + + +E+ L + G+ S+ D + E +K++ + Sbjct: 121 EASKQIALGLLSRRLDYVEDRLE-AGGPWLMGDRYSVADAYLSTVLGWCEYLKID--LSK 177 Query: 196 TPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQ 231 P++ ++ + P V A + +E Q LY Q Sbjct: 178 WPRILAYLERNQARPAVQAAMKAEGLIQA-ENLYFQ 212 >5F06-A nrPDB Length = 216 Score = 126 bits (317), Expect = 6e-30, Method: Composition-based stats. Identities = 43/208 (20%), Positives = 76/208 (36%), Gaps = 20/208 (9%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLK---NKPEWFFKKNPFGLVPVLENSQG 80 +++Y R L K + E++ ++L +K F KNPFG +P LE Sbjct: 2 LKLYGAPMSTCTSRVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDL 61 Query: 81 QLIYESAITCEYLDEAYPGKKL---LPDDPYEKACQKMILELFSK---------VPSLVG 128 ++ES Y+ E + G ++ E A K+ E+ S V + Sbjct: 62 T-LFESRAITSYIAEKFKGTGYDLIRHENLKEAASVKVWTEVESHRYNPAIAPIVFQFMV 120 Query: 129 SFIRSQNKEDYAGLK--EEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEA 186 + +R + + E+ K E L++ T + G+ S+ D P+ L Sbjct: 121 APLRGNSPDQTIIDDNVEKLGKVLDIYEAKLSS--TKYLAGDFYSLADLHHLPYTYYLMK 178 Query: 187 MKLNECVDHTPKLKLWMAAMKEDPTVSA 214 V+ P +K W + P Sbjct: 179 TPAASVVNERPHVKAWWEDISSRPAFKK 206 >2GDR-A nrPDB Length = 202 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 35/207 (16%), Positives = 82/207 (39%), Gaps = 20/207 (9%) Query: 24 IRIY----SMRFCPFAERTRLVLKAKGIRHEVININLKNKP----EWFFKKNPFGLVPVL 75 +++Y + P + L+ G+ E++ ++L +K + + + NP G VP L Sbjct: 1 MKLYYSPGACSLSP-----HIALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCL 55 Query: 76 ENSQGQLIYESAITCEYLDEAYPGKKLLPD-DPYEKACQKMILELFSKVPS--LVGSFIR 132 + G+ + E +Y+ + PGK+L P +E+ + L S F Sbjct: 56 QLDDGRTLTEGPAIVQYVADQVPGKQLAPANGSFERYHLQQWLNFISSELHKSFSPLFNP 115 Query: 133 SQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNEC 192 + + E +++ ++ L + G+ +S+ D ++ + ++ Sbjct: 116 ASSDEWKNAVRQSLNTRLGQVARQLE--HAPYLLGDQLSVADIYLFVVLGWSAYVNID-- 171 Query: 193 VDHTPKLKLWMAAMKEDPTVSALLTSE 219 + P L+ + + V + L +E Sbjct: 172 LSPWPSLQAFQGRVGGREAVQSALRAE 198 >2FHE-A nrPDB Length = 216 Score = 125 bits (313), Expect = 2e-29, Method: Composition-based stats. Identities = 42/193 (21%), Positives = 88/193 (45%), Gaps = 18/193 (9%) Query: 36 ERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGL----VPVLENSQGQLIYESAITCE 91 + RL+L+ G ++E + +WF KK GL +P + + + + +S Sbjct: 14 QPVRLLLEYLGEKYEEQIYERDDGEKWFSKKFELGLDLPNLPYYIDDKCK-LTQSLAILR 72 Query: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 Y+ + ++ E+A MI L R + + LKE + K+ Sbjct: 73 YIADK---HGMIGTTSEERARVSMIE---GAAVDLRQGISRISYQPKFEQLKEGYLKDLP 126 Query: 152 KLEEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEAMKLNE--CVDHTPKLKLWMAAMK 207 ++ ++ K + G S+S +D++++ E L+A++ E C+DH P L+ +M+ ++ Sbjct: 127 TTMKMWSDFLGKNPYLRGTSVSHVDFMVY---EALDAIRYLEPHCLDHFPNLQQFMSRIE 183 Query: 208 EDPTVSALLTSEK 220 P++ A + S + Sbjct: 184 ALPSIKAYMESNR 196 >2JL4-A nrPDB Length = 213 Score = 123 bits (309), Expect = 6e-29, Method: Composition-based stats. Identities = 39/212 (18%), Positives = 85/212 (40%), Gaps = 17/212 (8%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQ 79 +++Y+ + R R+ L KG+ +E + ++L ++ + F NP LVP L+ Sbjct: 1 KMKLYNFWRSGTSHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTG- 59 Query: 80 GQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFS-KVPSLVGSFIRSQNKED 138 Q++ +S E+L+E YP LLP D + + + + + + I ++ Sbjct: 60 AQVLIQSPAIIEWLEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEYLRKT 119 Query: 139 YAGLKEEFR--------KEFTKLEEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEAMK 188 + + F E +L K+ + G++ ++ D + P E + Sbjct: 120 FGADEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESARRFQ 179 Query: 189 LNECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 ++ + P ++ AA E + + Sbjct: 180 VD--LTPYPLIRAVDAACGELDAFRRAAPAAQ 209 >1F2E-A nrPDB Length = 201 Score = 122 bits (307), Expect = 1e-28, Method: Composition-based stats. Identities = 37/188 (19%), Positives = 70/188 (37%), Gaps = 11/188 (5%) Query: 39 RLVLKAKGIRHEVININLKNKP----EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLD 94 + L+ G E + ++L + E F NP G VP L G+ + E+ Y+ Sbjct: 15 HIALRETGADFEAVKVDLAVRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILLYIA 74 Query: 95 EAYPGKKLLP-DDPYEKACQKMILELFSKVPS--LVGSFIRSQNKEDYAGLKEEFRKEFT 151 + P L P + ++ L V F + + E A E + Sbjct: 75 DQNPASGLAPAEGSLDRYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAAAESVKNHLA 134 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPT 211 L++ L + + GN+ S+ D ++ + ++ + P L + + + P Sbjct: 135 ALDKELAGRD--HYAGNAFSVADIYLYVMLGWPAYVGID--MAAYPALGAYAGKIAQRPA 190 Query: 212 VSALLTSE 219 V A L +E Sbjct: 191 VGAALKAE 198 >3NIV-A nrPDB Length = 222 Score = 121 bits (303), Expect = 3e-28, Method: Composition-based stats. Identities = 45/211 (21%), Positives = 81/211 (38%), Gaps = 19/211 (9%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK-----PEWFFKKNPFGLVPVLEN 77 S+ +Y R R+ L K I +E I ++L N + + NP LVP L+ Sbjct: 2 SLILYDYFRSTACYRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDI 61 Query: 78 SQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFS-KVPSLVGSFIRSQNK 136 + GQ++ +S +YL+E +P LLP DP+ KA K + + + + L + ++ K Sbjct: 62 N-GQILSQSMAIIDYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRLK 120 Query: 137 EDYAGLKEEFRK--------EFTKLEEVLT--NKKTTFFGGNSISMIDYLIWPWFERLEA 186 E + +E+ + F EE L + G+ + + D + P Sbjct: 121 EQFNANEEQVLEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQVYNAHR 180 Query: 187 MKLNECVDHTPKLKLWMAAMKEDPTVSALLT 217 + + P + P Sbjct: 181 FHFD--MASYPIINEINEYCLTLPAFHDAAP 209 >3UBL-A nrPDB Length = 242 Score = 119 bits (297), Expect = 1e-27, Method: Composition-based stats. Identities = 41/167 (24%), Positives = 74/167 (44%), Gaps = 5/167 (2%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL 82 I+++ + + +L + KG+ +E I I ++ E F K +P G +PVLE G+ Sbjct: 3 MIKLHGASISNYVNKVKLGILEKGLEYEQIRIAP-SQEEDFLKISPMGKIPVLEM-DGKF 60 Query: 83 IYESAITCEYLDEAYP-GKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAG 141 I+ES E+LD +P KL+P+DP+E A + I + + I + Sbjct: 61 IFESGAILEFLDTIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSPE 120 Query: 142 LKEEFRKEFTKLEEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEA 186 + EE K + L + + + GN ++ D + L+ Sbjct: 121 IVEEVHSTLVKGIKALQRVVRFSPYIAGNVFTLADCSGFAHLSVLDE 167 >5EY6-A nrPDB Length = 217 Score = 116 bits (290), Expect = 9e-27, Method: Composition-based stats. Identities = 40/216 (18%), Positives = 76/216 (35%), Gaps = 21/216 (9%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLK---NKPEWFFKKNPFGLVPVLENSQG 80 +++Y R + L K + ++I +++ +K + K PFG VP ++ Sbjct: 4 VKVYGPPLSTAVSRVLVTLLEKDVPFQIIPVDMSKGEHKKPDYLKIQPFGQVPAFQDES- 62 Query: 81 QLIYESAITCEYLDEAYP---GKKLLPDDPYEKACQKMILELF-------SKVPSLVGSF 130 ++ES C Y+ E Y K L +P E+A +E S +F Sbjct: 63 ISLFESRSICRYVCEKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVFQLAF 122 Query: 131 IRSQNKEDYAGL----KEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERL-E 185 N G+ +E+ K E+ L ++ F G+ + D P + L Sbjct: 123 APRMNIPQDQGVIKQNEEKLGKVLDIYEQRLG--ESRFLAGDEFTFADLSHLPNGDYLVN 180 Query: 186 AMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKD 221 A + W + + + ++ K Sbjct: 181 ATDKGHLFTSRENVGRWWNEISDRESWKKVIEMRKS 216 >2D2Z-A nrPDB Length = 261 Score = 114 bits (286), Expect = 3e-26, Method: Composition-based stats. Identities = 43/181 (23%), Positives = 75/181 (41%), Gaps = 7/181 (3%) Query: 28 SMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESA 87 S+ CPF++R ++L KG+ V ++LK KP P G P ++ + Sbjct: 31 SIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPPFITFNSEVKTDVN 89 Query: 88 ITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFR 147 E+L+E K L P +++F+K ++I++ E L+ Sbjct: 90 KIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAK----FSAYIKNSRPEANEALERGLL 145 Query: 148 KEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMK 207 K KL+E L + NS+ I + + + E M L +C + PKL + K Sbjct: 146 KTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNE-MTLADC-NLLPKLHIVKVVAK 203 Query: 208 E 208 + Sbjct: 204 K 204 >2PVQ-A nrPDB Length = 201 Score = 112 bits (280), Expect = 1e-25, Method: Composition-based stats. Identities = 41/204 (20%), Positives = 78/204 (38%), Gaps = 14/204 (6%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPE----WFFKKNPFGLVPVLENSQ 79 +++Y + + ++L G+ +E+ ++LK K +F NP G VP LE Sbjct: 1 MKLY-YKVGAASLAPHIILSEAGLPYELEAVDLKAKKTADGGDYFAVNPRGAVPALEVKP 59 Query: 80 GQLIYESAITCEYLDEAYPGKKLLPD-DPYEKACQKMILELFSKVPSLVGS-FIRSQNKE 137 G +I ++A +Y+ + P E+A + L S + + F + ++E Sbjct: 60 GTVITQNAAILQYIGDHSDVAAFKPAYGSIERARLQEALGFCSDLHAAFSGLFAPNLSEE 119 Query: 138 DYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYL--IWPWFERLEAMKLNECVDH 195 AG+ + +LE +L++K + G + Y I W + + Sbjct: 120 ARAGVIANINRRLGQLEAMLSDKNAYWLGDDFTQPDAYASVIIGW-----GVGQKLDLSA 174 Query: 196 TPKLKLWMAAMKEDPTVSALLTSE 219 PK + P V E Sbjct: 175 YPKALKLRERVLARPNVQKAFKEE 198 >4RI7-A nrPDB Length = 215 Score = 111 bits (278), Expect = 2e-25, Method: Composition-based stats. Identities = 45/210 (21%), Positives = 69/210 (32%), Gaps = 14/210 (6%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLK---NKPEWFFKKNPFGLVPVLENSQG 80 + IY C R L K + +I I+L K + K PFG VP ++ Sbjct: 5 VTIYGPPLCTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDES- 63 Query: 81 QLIYESAITCEYLDEAYPG---KKLLPDDPYEKACQKMILE-----LFSKVPSLVGSFIR 132 ++ES C Y+ + Y K L D KA +E LV + Sbjct: 64 ITLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFGPPSGDLVHDLLF 123 Query: 133 SQNKEDYAGLKEEFRKEFTKLEEVLTN-KKTTFFGGNSISMIDYLIWPWFERL-EAMKLN 190 S D A +K+ K L+ +T F G+ S D P + L + Sbjct: 124 SSVPVDEALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADLSHLPNGDYLVNSTDKG 183 Query: 191 ECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 + W + + +L K Sbjct: 184 YLFTSRKNVNRWWTEISNRESWKKVLEMRK 213 >6JWK-A nrPDB Length = 222 Score = 111 bits (278), Expect = 3e-25, Method: Composition-based stats. Identities = 39/210 (18%), Positives = 81/210 (38%), Gaps = 15/210 (7%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWF---FKKNPFGLVPVLENSQG 80 +++YS + R R+ L KG+ ++V+ +NL+ + ++NP G +P L ++ G Sbjct: 1 MQLYSFFNSSTSYRVRIALALKGLDYQVVPVNLRQGEQLRPADRQRNPMGALPTLVDADG 60 Query: 81 QLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFS-KVPSL-------VGSFIR 132 + +S +YLD P +L+P DP +A + L + + L + + Sbjct: 61 RRFSQSLAIIDYLDAVQPEPRLIPLDPLHRAQALELALLVACDIHPLNNVRVLKYLTQVL 120 Query: 133 SQNKEDYAGLKE-EFRKEFTKLEEVLT-NKKTTFFGGNSISMIDYLIWPWFERLEAMKLN 190 + ED + E +L +++ FF G + +++ + P M + Sbjct: 121 GIDAEDRQRWYAHWVAEGLAAAETLLNRHRRGAFFAGAAAGIVECCLVPQLANARRMGCD 180 Query: 191 ECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 + P L + Sbjct: 181 --LAPYPALLELEGRCLALEAFQRASPERQ 208 >1AXD-A nrPDB Length = 209 Score = 110 bits (276), Expect = 5e-25, Method: Composition-based stats. Identities = 40/203 (19%), Positives = 79/203 (38%), Gaps = 13/203 (6%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 +++Y R L+ G +E++ IN ++K +NPFG VP L++ Sbjct: 3 MKLYGAVMSWNLTRCATALEEAGSDYEIVPINFATAEHKSPEHLVRNPFGQVPALQDGDL 62 Query: 81 QLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILEL----FSKVPSLVGSFIRSQNK 136 ++ES C+Y + L + E A + +E+ ++ + + + Sbjct: 63 -YLFESRAICKYAARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLISPM 121 Query: 137 EDYAGLKEEFRKEFTKLEEVLTN-----KKTTFFGGNSISMIDYLIWPWFERLEAMKLNE 191 ++ + KL++VL K + G+ +S+ D L A Sbjct: 122 LGGTTDQKVVDENLEKLKKVLEVYEARLTKCKYLAGDFLSLADLNHVSVTLCLFATPYAS 181 Query: 192 CVDHTPKLKLWMAAMKEDPTVSA 214 +D P +K W + + E P+V Sbjct: 182 VLDAYPHVKAWWSGLMERPSVQK 204 >6F05-A nrPDB Length = 215 Score = 110 bits (275), Expect = 6e-25, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 79/207 (38%), Gaps = 19/207 (9%) Query: 24 IRIYS-MRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQ 79 +++Y P +R + L KG+ E I ++L ++K + PFG VP + + Sbjct: 3 LKVYGPHFASP--KRALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGD 60 Query: 80 GQLIYESAITCEYLDEAY--PGKKLLPDDPYEKACQKMILELFSKV--PSLVGSFIRSQN 135 + I+ES Y+ E Y G LL ++ + L++ + P L+ + Sbjct: 61 YK-IFESRAVMRYVAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMF 119 Query: 136 KED--YAGLKEEFRKEFTKLEEVLTN-----KKTTFFGGNSISMIDYLIWPWFERLEA-M 187 + ++ ++ KL VL K+ + G+ +S+ D P+ + L + Sbjct: 120 ASVMGFPSDEKLIKESEEKLAGVLDVYEAHLSKSKYLAGDFVSLADLAHLPFTDYLVGPI 179 Query: 188 KLNECVDHTPKLKLWMAAMKEDPTVSA 214 + + W + P Sbjct: 180 GKAYMIKDRKHVSAWWDDISSRPAWKE 206 >3LG6-A nrPDB Length = 235 Score = 109 bits (273), Expect = 9e-25, Method: Composition-based stats. Identities = 43/222 (19%), Positives = 83/222 (37%), Gaps = 24/222 (10%) Query: 16 PGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPE---WFFKKNPFGLV 72 PG + + +Y + R R+ K I + +NL + + NP V Sbjct: 2 PGSMTTPNFELYGYFRSSCSGRLRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTV 61 Query: 73 PVLENSQ----------GQLIYESAITCEYLDEAYPG--KKLLPD--DPYEKACQKMILE 118 P+L S I +S EYL+EA P + LLP +P +A + I Sbjct: 62 PLLVVSNINNTVSPSSASFSIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICN 121 Query: 119 LFSKVPSLVGSF-----IRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMI 173 + + V + +++ + + ++ + F +E++L F G+ I++ Sbjct: 122 IIACDVQPVTNLKIQKKVKALDGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLA 181 Query: 174 DYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSAL 215 D + P E + ++ + P K M ++ V Sbjct: 182 DVCLVPAVWAAERVGMD--LARFPITKRVFEEMLKEEAVQKA 221 >5F05-A nrPDB Length = 212 Score = 109 bits (273), Expect = 9e-25, Method: Composition-based stats. Identities = 40/206 (19%), Positives = 77/206 (37%), Gaps = 14/206 (6%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 ++++ +R L K + E++N+NL ++K E NPFG VP + Sbjct: 3 LKLHGSVLSTNTQRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDL 62 Query: 81 QLIYESAITCEYLDEAYPGKKL-LPDDPYEKACQKMILELFSKVPSL-VGSFIRSQNKED 138 + ++ES +Y+ Y K L A + E+ S + Q + Sbjct: 63 K-LFESRAISQYVAHQYASKGTQLGAAGNGYATILVWQEVESHQFDPSASKLVWEQVFKP 121 Query: 139 YAGLKEE---FRKEFTKLEEVLTN-----KKTTFFGGNSISMIDYLIWPWFERLEAMKLN 190 GL + + L +VL ++ + +S ++ D P + L Sbjct: 122 VFGLPTDAALVAETEVTLGKVLDVYEARLSQSKYLASDSFTLADLHHLPNIQALLGTPSK 181 Query: 191 ECVDHTPKLKLWMAAMKEDPTVSALL 216 + D P + W+A++ P +L Sbjct: 182 KLFDSRPHVSAWVASITGRPAWGKVL 207 >4PTS-A nrPDB Length = 348 Score = 106 bits (265), Expect = 8e-24, Method: Composition-based stats. Identities = 52/257 (20%), Positives = 99/257 (38%), Gaps = 41/257 (15%) Query: 18 PVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININL----KNKPEWFFKKNPFGLVP 73 PV G R+ + R CP+A RT +V + G+ + V+++ L +K W F +P G+ P Sbjct: 42 PVEPGRYRLIAARACPWANRTLIVRRLLGLEN-VLSLGLCGPTHDKNSWTFDLDPGGVDP 100 Query: 74 VLENSQGQLIYESA-------ITCEYLDEAYPGKKLLPDDPYEKACQKMILELF--SKVP 124 VL + + YE IT + E G+ + D P + + P Sbjct: 101 VLGIPRLKDAYEKRFPGYPKGITVPAVVEIATGEVVTNDFPQITIDFSLEWTAYHRDGAP 160 Query: 125 SLVGSFIRSQNKEDYAGLKEE--------------------FRKEFTKLEEVLTN-KKTT 163 L +R++ E G+ E + + FTKL+E+ + Sbjct: 161 QLYPEHLRAEIDEVSKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLFTKLDELSERLAQQR 220 Query: 164 FFGGNSISMIDYLIWPWFERLEAM--KLNEC----VDHTPKLKLWMAAMKEDPTVSALLT 217 + G++I+ D ++ R +A+ +C + P L + + + P Sbjct: 221 YLVGDTITEADVRLFTTLARFDAVYHGHFKCNRSKLSEMPVLWAYARDLFQTPGFGDTTD 280 Query: 218 SEKDWQGFLELYLQNSP 234 + Q + ++ +P Sbjct: 281 FTQIKQHYYIVHSDINP 297 >1JLV-A nrPDB Length = 209 Score = 104 bits (258), Expect = 5e-23, Method: Composition-based stats. Identities = 39/218 (17%), Positives = 78/218 (35%), Gaps = 19/218 (8%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 + Y + ++ A G+ + NL ++ F K NP +P L ++ G Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVELNLKLTNLMAGEHMKPEFLKINPQHCIPTLVDN-G 59 Query: 81 QLIYESAITCEYLDEAY-PGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRS------ 133 ++ES C YL E Y KL P DP ++A L + +L F Sbjct: 60 FALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYF--DMGTLYQRFADYYYPQIF 117 Query: 134 QNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECV 193 + A +++ + L L K + G+S+++ D + + + Sbjct: 118 AKQPANAENEKKMKDAVDFLNTFLDGHK--YVAGDSLTIADLTVLATVSTYDVAGFE--L 173 Query: 194 DHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQ 231 P + W +++ +E + F + + + Sbjct: 174 AKYPHVAAWYERTRKE--APGAAINEAGIEEFRKYFEK 209 >1PN9-A nrPDB Length = 209 Score = 100 bits (249), Expect = 6e-22, Method: Composition-based stats. Identities = 37/196 (18%), Positives = 71/196 (36%), Gaps = 17/196 (8%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQG 80 + Y + ++ A G+ + +L ++ F K NP +P L ++ G Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVELNLKLTDLMKGEHMKPEFLKLNPQHCIPTLVDN-G 59 Query: 81 QLIYESAITCEYLDEAY-PGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDY 139 ++ES YL E Y KL P DP ++A L + +L F + + Sbjct: 60 FALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYF--DMGTLYQRFADYHYPQIF 117 Query: 140 AGL------KEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECV 193 A +++ + L L ++ + GN +++ D + E + Sbjct: 118 AKQPANPENEKKMKDAVGFLNTFLEGQE--YAAGNDLTIADLSLAATIATYEVAGFD--F 173 Query: 194 DHTPKLKLWMAAMKED 209 P + W A K + Sbjct: 174 APYPNVAAWFARCKAN 189 >1N2A-A nrPDB Length = 201 Score = 99.0 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 43/204 (21%), Positives = 86/204 (42%), Gaps = 14/204 (6%) Query: 24 IRI-YSMRFCPFAERTRLVLKAKGIRHEVININLKNKP----EWFFKKNPFGLVPVLENS 78 +++ Y C A + L+ G +++++L K + +F NP G VP L Sbjct: 1 MKLFYKPGACSLAS--HITLRESGKDFTLVSVDLMKKRLENGDDYFAVNPKGQVPALLLD 58 Query: 79 QGQLIYESAITCEYLDEAYPGKKLL-PDDPYEKACQKMILELFS-KVPSLVGSFIRSQNK 136 G L+ E +YL ++ P ++LL P + + L + ++ R Sbjct: 59 DGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIATELHKGFTPLFRPDTP 118 Query: 137 EDYA-GLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDH 195 E+Y ++ + K+ + E L ++ + G ++ D ++ A+KLN ++ Sbjct: 119 EEYKPTVRAQLEKKLQYVNEALKDEH--WICGQRFTIADAYLFTVLRWAYAVKLN--LEG 174 Query: 196 TPKLKLWMAAMKEDPTVSALLTSE 219 + +M M E P V L++E Sbjct: 175 LEHIAAFMQRMAERPEVQDALSAE 198 >3C8E-A nrPDB Length = 288 Score = 98.6 bits (244), Expect = 2e-21, Method: Composition-based stats. Identities = 41/242 (16%), Positives = 89/242 (36%), Gaps = 34/242 (14%) Query: 2 SGESARSLGKGSAPP-----GPVPEGSIRIYSMRFCPFAERTRLVLKAK------GIRHE 50 +G + ++ + + P PV + +++YS+ P ++ ++L+ G ++ Sbjct: 18 AGGAFANINRPVSGPTHEKTLPVGKHPLQLYSLGT-PNGQKVTIMLEELLALGVTGAEYD 76 Query: 51 VININLKNKPEW---FFKKNPFGLVPVLENSQGQL---IYESAITCEYLDEAYPGKKLLP 104 I + + ++ F + NP +P L + ++ES YL E + LP Sbjct: 77 AWLIRIGDGDQFSSGFVEVNPNSKIPALRDHTHNPPIRVFESGSILLYLAEKFG--YFLP 134 Query: 105 DDPYEKACQKMILELFSKVPSLVGS-------FIRSQNKEDYAGLKEEFRKEFTKLEEVL 157 D ++ L +G + + + E ++ L++ L Sbjct: 135 QDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQL 194 Query: 158 TNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVD-----HTPKLKLWMAAMKEDPTV 212 K F G+ ++ D IWPWF + + + + ++ W + E P V Sbjct: 195 AQHK--FVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAV 252 Query: 213 SA 214 Sbjct: 253 KR 254 >5ZWP-A nrPDB Length = 208 Score = 97.5 bits (241), Expect = 4e-21, Method: Composition-based stats. Identities = 39/194 (20%), Positives = 67/194 (34%), Gaps = 17/194 (8%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLENSQG 80 + Y + + KA GI +NL+ F K NP +P L + Sbjct: 1 MDFYYLPGSAPCRSVLMTAKALGIELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDGDF 60 Query: 81 QLIYESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDY 139 ++ES YL E Y L P P ++A L + +L SF + + Sbjct: 61 -ALWESRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYF--DMGTLYKSFADYYYPQIF 117 Query: 140 AGLK------EEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECV 193 A ++ F L L + + G+S+++ D + E + + Sbjct: 118 AKAPADPELFKKIETAFDFLNTFLKGHE--YAAGDSLTVADLALLASVSTFEVASFD--I 173 Query: 194 DHTPKLKLWMAAMK 207 P + W A +K Sbjct: 174 SKYPNVAKWYANLK 187 >2WRT-A nrPDB Length = 218 Score = 95.6 bits (236), Expect = 2e-20, Method: Composition-based stats. Identities = 34/170 (20%), Positives = 76/170 (44%), Gaps = 14/170 (8%) Query: 57 KNKPEWFFKKNPFGL----VPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKAC 112 ++ +W K GL +P + + + + +S Y+ + +L P E+A Sbjct: 36 DDREKWLGDKFNMGLDLPNLPYYIDDKCK-LTQSVAIMRYIADK---HGMLGSTPEERAR 91 Query: 113 QKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTN--KKTTFFGGNSI 170 MI L F+R + +K ++ KE ++ +N + G+S+ Sbjct: 92 ISMIE---GAAMDLRMGFVRVCYNPKFEEVKGDYLKELPTTLKMWSNFLGDRHYLTGSSV 148 Query: 171 SMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 S +D++++ + + + +C++ PKLK + + +++ P + A + SEK Sbjct: 149 SHVDFMVYEALDCIRYLAP-QCLEDFPKLKEFKSRIEDLPKIKAYMESEK 197 >3MAK-A nrPDB Length = 209 Score = 94.0 bits (232), Expect = 5e-20, Method: Composition-based stats. Identities = 40/212 (18%), Positives = 72/212 (33%), Gaps = 18/212 (8%) Query: 27 YSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLENSQGQLI 83 Y + + KA G+ +NL+ F K NP +P L ++ G + Sbjct: 5 YYLPGSSPCRSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDN-GFAL 63 Query: 84 YESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGL 142 +ES YL E Y L P P ++A L + +L SF + +A Sbjct: 64 WESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYF--DMGTLYQSFANYYYPQVFAKA 121 Query: 143 K------EEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHT 196 ++ F L L + + G+S+++ D + E K + Sbjct: 122 PADPEAFKKIEAAFEFLNTFLEGQD--YAAGDSLTVADIALVATVSTFEVAKFE--ISKY 177 Query: 197 PKLKLWMAAMKE-DPTVSALLTSEKDWQGFLE 227 + W K+ P +++ + E Sbjct: 178 ANVNRWYENAKKVTPGWEENWAGCLEFKKYFE 209 >4IKH-A nrPDB Length = 244 Score = 94.0 bits (232), Expect = 5e-20, Method: Composition-based stats. Identities = 39/228 (17%), Positives = 82/228 (35%), Gaps = 25/228 (10%) Query: 17 GPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPE---WFFKKNPFGLVP 73 I++YS+ P + ++L+ G+ +E ++ + + + F +P +P Sbjct: 16 PAQFPEWIQLYSLPT-PNGVKVSIMLEEIGLPYEAHRVSFETQDQMTPEFLSVSPNNKIP 74 Query: 74 VLENSQGQ-----LIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILEL----FSKVP 124 + + G ++ES YL + +LL + + L + Sbjct: 75 AILDPHGPGDQPLALFESGAILIYLADKSG--QLLAQESAARYETIQWLMFQMGGIGPMF 132 Query: 125 SLVGSFIRSQNKE-----DYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP 179 VG F + +E E ++ L++ L ++ + G ++ D +P Sbjct: 133 GQVGFFNKFAGREYEDKRPLERYVNEAKRLLGVLDKHLGGRE--WIMGERYTIADIATFP 190 Query: 180 WFERLEAM---KLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQG 224 W L +D+ P++K +A P V L K +G Sbjct: 191 WIRNLIGFYEAGELVGIDNFPEVKRVLAKFVARPAVIRGLEIPKVSEG 238 >5F0G-A nrPDB Length = 215 Score = 93.2 bits (230), Expect = 8e-20, Method: Composition-based stats. Identities = 42/215 (19%), Positives = 69/215 (32%), Gaps = 16/215 (7%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLENSQG 80 + Y M +V KA G+ +N F K NP +P L ++ G Sbjct: 1 MDFYYMPGGGGCRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLVDN-G 59 Query: 81 QLIYESAITCEYLDEAY-PGKKLLPDDPYEKACQKMIL-----ELFSKVPSLVGSFIRSQ 134 I+ES YL E Y LLP+DP ++A L L+ R+ Sbjct: 60 FSIWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFDMGTLYESFAKYYYPLFRTG 119 Query: 135 NKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVD 194 LK F L+ L ++ + G+ +++ D I E + + Sbjct: 120 KPGSDEDLKR-IETAFGFLDTFLEGQE--YVAGDQLTVADIAILSTVSTFEVSEFD--FS 174 Query: 195 HTPKLKLWMAAMKE-DPTVSALLTSEKDWQGFLEL 228 + W K+ P + + Sbjct: 175 KYSNVSRWYDNAKKVTPGWDENWEGLMAMKALFDA 209 >3GX0-A nrPDB Length = 215 Score = 92.9 bits (229), Expect = 1e-19, Method: Composition-based stats. Identities = 38/210 (18%), Positives = 76/210 (36%), Gaps = 23/210 (10%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK---PEWFFKKNPFGLVPVLEN-- 77 I +Y P + L L+ + + +I ++L F + +P +P + + Sbjct: 1 MIDLYFAPT-PNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHS 59 Query: 78 --SQGQLI--YESAITCEYLDEAYPGKKLLPDDPYEKA--CQKMILELFSKVPSLVGSF- 130 G+ + +ES YL E L + E+A Q + ++ P L + Sbjct: 60 PADGGEPLSLFESGAILLYLAEKTG--LFLSHETRERAATLQWLFWQVGGLGPMLGQNHH 117 Query: 131 ----IRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEA 186 + E ++ + L + L N + + GG + S+ D WPW Sbjct: 118 FNHAAPQTIPYAIERYQVETQRLYHVLNKRLEN--SPWLGGENYSIADIACWPWVNAWTR 175 Query: 187 MKLNECVDHTPKLKLWMAAMKEDPTVSALL 216 +++ + P +K W ++ P L Sbjct: 176 QRID--LAMYPAVKNWHERIRSRPATGQAL 203 >1V2A-A nrPDB Length = 210 Score = 92.5 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 37/206 (17%), Positives = 82/206 (39%), Gaps = 21/206 (10%) Query: 27 YSMRFCPFAERTRLVLKAKGIRHEVININLKN--KPEWFFKKNPFGLVPVLENSQGQLIY 84 Y P + L+ K GI + N+ + + + K NP +P L ++ G +++ Sbjct: 4 YYSLISPPCQSAILLAKKLGITLNLKKTNVHDPVERDALTKLNPQHTIPTLVDN-GHVVW 62 Query: 85 ESAITCEYLDEAY-PGKKLLPDDPYEKACQKM-----ILELFSKVPSLVGSFIRSQNKED 138 ES YL E Y L P DP ++ I L+ ++ ++ ++ + D Sbjct: 63 ESYAIVLYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIGTLYKRIIDVIHLVMKKEQPSD 122 Query: 139 YAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPK 198 E+ + LE+ +T + + + +++ D + L +K + ++ P Sbjct: 123 EQ--MEKLKGALDLLEQFVTERA--YAAADHLTVADICLLGTVTALNWLKHD--LEPFPH 176 Query: 199 LKLWMAAMKEDPTVSALLTSEKDWQG 224 ++ W+ V A + +++ Sbjct: 177 IRAWLER------VRAEMPDYEEFSK 196 >4MPF-A nrPDB Length = 266 Score = 90.5 bits (223), Expect = 5e-19, Method: Composition-based stats. Identities = 35/201 (17%), Positives = 70/201 (34%), Gaps = 20/201 (9%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQ 79 + ++ + + K GI E+ ++L ++K + F + N G +P L++ Sbjct: 24 GLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGD 83 Query: 80 GQLIYESAITCEYLDEAYPGK-KLLPDDPYEKACQKMILELFSK-----------VPSLV 127 ++ ES+ YL Y P D +A L + V L Sbjct: 84 F-ILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG 142 Query: 128 GSFIRSQNKEDYAGLKEEFRKEFTKLE-EVLTNKKTTFFGGNSISMIDYLIWPWFERLEA 186 KE + + LE + L ++ F G +++ D + + A Sbjct: 143 PLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDR--PFLAGQQVTLADLMALEELMQPVA 200 Query: 187 MKLNECVDHTPKLKLWMAAMK 207 + E + P+L W ++ Sbjct: 201 LGY-ELFEGRPRLAAWRGRVE 220 >5Y7I-A nrPDB Length = 261 Score = 90.5 bits (223), Expect = 5e-19, Method: Composition-based stats. Identities = 34/217 (15%), Positives = 78/217 (35%), Gaps = 27/217 (12%) Query: 28 SMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESA 87 ++ CPF +R +VL KG++ V ++++ KP P G P G L + Sbjct: 42 NVGNCPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLAP-GTNPPFLLYNGTLKTDFI 100 Query: 88 ITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFR 147 E+L++ + P+ K ++ + + + +FI++ ++ Sbjct: 101 KIEEFLEQTLAPPRY----PHLSPVNKESFDVGADIFAKFSAFIKNSPNNPLQ--EKNLL 154 Query: 148 KEFTKLEEVLTNK----------------KTTFFGGNSISMIDYLIWPWFERLEAMK--- 188 +EF +L++ L + F G+ +++ D + P + Sbjct: 155 REFKRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLLPKLHVIRVAAKKY 214 Query: 189 -LNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQG 224 E DH + ++ E ++ + + Sbjct: 215 CNFEIPDHFTGVWRYLKNADERDEFKQTCPADIEIEK 251 >3GH6-A nrPDB Length = 210 Score = 89.8 bits (221), Expect = 9e-19, Method: Composition-based stats. Identities = 36/214 (16%), Positives = 66/214 (30%), Gaps = 15/214 (7%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININ----LKNKPEWFFKKNPFGLVPVLENSQ 79 + +Y + KA G+ + I + + K NP +P L + Sbjct: 1 MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTL-HDH 59 Query: 80 GQLIYESAITCEYLDEAY-PGKKLLPDDPYEKACQKMILELFSKVPS-LVGSFIRSQNKE 137 G ++ES YL E Y KL P D ++A L + Q Sbjct: 60 GFALWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKSFSEYYYPQIFL 119 Query: 138 DYAGLKEEFRK---EFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVD 194 +E ++K F L L + T+ G S+ D + + Sbjct: 120 KKPANEENYKKIEVAFEFLNTFLEGQ--TYSAGGDYSLADIAFLATVSTFDVAGFD--FK 175 Query: 195 HTPKLKLWMAAMKED-PTVSALLTSEKDWQGFLE 227 + W K+ P ++++ + + Sbjct: 176 RYANVARWYENAKKLTPGWEENWAGCQEFRKYFD 209 >1VF1-A nrPDB Length = 229 Score = 88.2 bits (217), Expect = 3e-18, Method: Composition-based stats. Identities = 36/187 (19%), Positives = 72/187 (38%), Gaps = 11/187 (5%) Query: 38 TRLVLKAKGIRHEVININLKNKPEWFFK--KNPFGLVPVLENSQGQLIYESAITCEYLDE 95 R +L A G+ E + + + + E + F VP++E +L+ ++ Y+ Sbjct: 19 IRWLLAAAGVEFEEVFLETREQYEKLLQSGILMFQQVPMVEIDGMKLV-QTRAILNYIAG 77 Query: 96 AYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAG----LKEEFRKEFT 151 Y L D E+A M + + + SF ++ +++ + F Sbjct: 78 KY---NLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKVKQCAFVVEKATSRYFP 134 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPT 211 E+VL + F GN +S D + +E K ++ + P L+ + + PT Sbjct: 135 AYEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEE-KKSDALSGFPLLQAFKKRISSIPT 193 Query: 212 VSALLTS 218 + L Sbjct: 194 IKKFLAP 200 >3LSZ-A nrPDB Length = 225 Score = 88.2 bits (217), Expect = 3e-18, Method: Composition-based stats. Identities = 34/219 (15%), Positives = 67/219 (30%), Gaps = 31/219 (14%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVINI--------------NLKNKPEWFFKKNP 68 S++IY + + L L + E + + L + NP Sbjct: 2 SLKIYGVYRSRASRPLWL-LAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNP 60 Query: 69 FGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVP---- 124 G +P LE +G ++ ES ++ G +L P E A + Sbjct: 61 LGQIPCLE-EEGLILTESLAITLHIARTQGG-QLGPRSEPEDALMVSWSLFAATAVEPPA 118 Query: 125 ---SLVGSFIRSQNKEDYAG---LKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIW 178 L+ + E A E R+ +LE + + G ++ D + Sbjct: 119 LEIQLIQRSGGGTSPEGQAAIAIAAERLRRPLARLERHFAAED--YLVGGRFTVADLNLA 176 Query: 179 PWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLT 217 +A ++ P + W+ + P ++ Sbjct: 177 ETLRYGQA--HPALLEPFPAVAAWLDRCQSRPAFRLMME 213 >1FHE-A nrPDB Length = 217 Score = 87.1 bits (214), Expect = 6e-18, Method: Composition-based stats. Identities = 41/192 (21%), Positives = 85/192 (44%), Gaps = 14/192 (7%) Query: 35 AERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGL----VPVLENSQGQLIYESAITC 90 A+ RL L+ G +E ++ +W +K GL +P + + + + +S Sbjct: 13 AQPVRLFLEYLGEEYEEHLYGRDDREKWMSEKFNMGLDLPNLPYYIDDKCK-LTQSVAIM 71 Query: 91 EYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEF 150 Y+ + +L P E+A MI L F R + +KEE+ KE Sbjct: 72 RYIADK---HGMLGTTPEERARISMIE---GAAMDLRIGFGRVCYNPKFEEVKEEYVKEL 125 Query: 151 TKLEEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 K ++ ++ + G+S+S +D++++ + + + C+D PKLK + + ++ Sbjct: 126 PKTLKMWSDFLGDRHYLTGSSVSHVDFMLYETLDSIRYLAP-HCLDEFPKLKEFKSRIEA 184 Query: 209 DPTVSALLTSEK 220 P + A + S++ Sbjct: 185 LPKIKAYMESKR 196 >1G6W-A nrPDB Length = 261 Score = 87.1 bits (214), Expect = 7e-18, Method: Composition-based stats. Identities = 40/246 (16%), Positives = 76/246 (30%), Gaps = 47/246 (19%) Query: 20 PEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLE 76 P ++S R P + +VL G + I ++ +++ F NP VP L Sbjct: 17 PLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALI 76 Query: 77 N--SQGQLIYESAITCEYLDEAY---PGKKLLPDDPYE---KACQKMILELFSKVPSLVG 128 + I+ES +L Y G LL D + + + P + Sbjct: 77 DHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQ 136 Query: 129 S-----FIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKK---------------------- 161 + F + +E R+ + +E L ++ Sbjct: 137 ALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPM 196 Query: 162 --------TTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVS 213 + G+ +++ D PW ++ + + P++ W M P V Sbjct: 197 SQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGI-NIKIEFPEVYKWTKHMMRRPAVI 255 Query: 214 ALLTSE 219 L E Sbjct: 256 KALRGE 261 >4GTU-A nrPDB Length = 217 Score = 85.5 bits (210), Expect = 2e-17, Method: Composition-based stats. Identities = 38/201 (18%), Positives = 78/201 (38%), Gaps = 19/201 (9%) Query: 35 AERTRLVLKAKGIRHEVININLKNKP-----EWFFKKNPFGL----VPVLENSQGQLIYE 85 A RL+L+ +E + + P +W +K GL +P L + + I + Sbjct: 13 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHK-ITQ 71 Query: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE 145 S Y+ L + EK ++ ++ + R D+ LK E Sbjct: 72 SNAILCYIARK---HNLCGETEEEKIRVDILE---NQAMDVSNQLARVCYSPDFEKLKPE 125 Query: 146 FRKEFTKLEEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWM 203 + +E + + + K +F G+ I+ +D+L + + + C+D P LK ++ Sbjct: 126 YLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEP-NCLDAFPNLKDFI 184 Query: 204 AAMKEDPTVSALLTSEKDWQG 224 + + +SA + S + Sbjct: 185 SRFEGLEKISAYMKSSRFLPK 205 >2R5G-A nrPDB Length = 247 Score = 85.2 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 36/216 (16%), Positives = 78/216 (36%), Gaps = 25/216 (11%) Query: 28 SMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESA 87 S+ CPF +R ++L KG++ V +++ KPE P G P +L + Sbjct: 26 SIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAP-GTNPPFLVYNKELKTDFI 84 Query: 88 ITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFR 147 E+L++ + P K + LF+K ++I++ KE ++ Sbjct: 85 KIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAK----FSAYIKNTQKEANKNFEKSLL 140 Query: 148 KEFTKLEEVLTNK----------------KTTFFGGNSISMIDYLIWPWF----ERLEAM 187 KEF +L++ L + F G+ +++ D + P + Sbjct: 141 KEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKY 200 Query: 188 KLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQ 223 + + + ++ + +K+ + Sbjct: 201 RDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIE 236 >1F3B-A nrPDB Length = 222 Score = 84.8 bits (208), Expect = 3e-17, Method: Composition-based stats. Identities = 38/190 (20%), Positives = 67/190 (35%), Gaps = 17/190 (8%) Query: 38 TRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-----LVPVLENSQGQLIYESAITCEY 92 R +L A G+ E I PE K G VP++E + + ++ Y Sbjct: 18 IRWLLAAAGVEFEEKFI---QSPEDLEKLKKDGNLMFDQVPMVEIDGMK-LAQTRAILNY 73 Query: 93 LDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFI--RSQNKEDYAGLKEEFRK-- 148 + Y L D E+A M E + ++G + +E L ++ K Sbjct: 74 IATKYD---LYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKTALAKDRTKNR 130 Query: 149 EFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 E+VL + + GN ++ +D + +E + P LK + + + Sbjct: 131 YLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFD-ASLLTPFPLLKAFKSRISS 189 Query: 209 DPTVSALLTS 218 P V L Sbjct: 190 LPNVKKFLQP 199 >2DC5-A nrPDB Length = 231 Score = 83.6 bits (205), Expect = 8e-17, Method: Composition-based stats. Identities = 36/200 (18%), Positives = 78/200 (39%), Gaps = 19/200 (9%) Query: 35 AERTRLVLKAKGIRHEVININLKNKP-----EWFFKKNPFGL----VPVLENSQGQLIYE 85 A RL L+ +E + + P +W +K GL +P L + + I + Sbjct: 21 AHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLPYLIDGSHK-ITQ 79 Query: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE 145 S YL L + E+ ++ +++ R D+ LK Sbjct: 80 SNAILRYLGRK---HNLCGETEEERIRVDILE---NQLMDNRMVLARLCYNADFEKLKPG 133 Query: 146 FRKEFTKLEEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWM 203 + ++ + + + K +F G+ I+ +D++ + ER + + +C+D P LK ++ Sbjct: 134 YLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFE-AKCLDAFPNLKDFI 192 Query: 204 AAMKEDPTVSALLTSEKDWQ 223 A + +S + + + Sbjct: 193 ARFEGLKKISDYMKTSRFLP 212 >4K0G-A nrPDB Length = 251 Score = 83.2 bits (204), Expect = 9e-17, Method: Composition-based stats. Identities = 32/215 (14%), Positives = 79/215 (36%), Gaps = 25/215 (11%) Query: 29 MRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAI 88 + PF++R +VL KG+ V ++ K + E K P G +P L ++ ++ Sbjct: 31 IGNSPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGT-EVHTDTNK 89 Query: 89 TCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRK 148 E+L+ + L++F+K ++I++ N L++ K Sbjct: 90 IEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAK----FSAYIKNSNPALNDNLEKGLLK 145 Query: 149 EFTKLEEVLTNK----------------KTTFFGGNSISMIDYLIWPWFERLEAM----K 188 L+ LT+ + F GN +++ D + P ++ + + Sbjct: 146 ALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYR 205 Query: 189 LNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQ 223 + + +++ ++ +++ + Sbjct: 206 GFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIE 240 >3M1G-A nrPDB Length = 362 Score = 83.2 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 53/276 (19%), Positives = 101/276 (36%), Gaps = 53/276 (19%) Query: 9 LGKGSAPPG--------PVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININL---- 56 + GS P PV G R+ + R CP+A RT + + G+ + VI++ L Sbjct: 39 VPAGSEPIAQEDGTFHWPVEAGRYRLVAARACPWAHRTVITRRLLGLEN-VISLGLTGPT 97 Query: 57 KNKPEWFFKKNPFGLVPVLENSQGQLIYESA-------ITCEYLDEAYPGKKLLPDDPYE 109 + W F +P L PVL+ + Q Y + IT L E K + D P Sbjct: 98 HDVRSWTFDLDPNHLDPVLQIPRLQDAYFNRFPDYPRGITVPALVEESSKKVVTNDYPSI 157 Query: 110 KACQKMILELFSK--VPSLVGSFIRSQ-----------------------NKEDYAGLKE 144 + + F + P+L + +R + ++E + + Sbjct: 158 TIDFNLEWKQFHREGAPNLYPAELREEMAPVMKRIFTEVNNGVYRTGFAGSQEAHNEAYK 217 Query: 145 EFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAM--KLNEC----VDHTPK 198 LE+ L+ + + G+ I+ D ++P R +A+ +C + P Sbjct: 218 RLWVALDWLEDRLSTR--RYLMGDHITEADIRLYPTLVRFDAVYHGHFKCGRNKITEMPN 275 Query: 199 LKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSP 234 L ++ + + P + Q + + + +P Sbjct: 276 LWGYLRDLFQTPGFGDTTDFTEIKQHYYITHAEINP 311 >3FY7-A nrPDB Length = 250 Score = 82.5 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 31/213 (14%), Positives = 75/213 (35%), Gaps = 16/213 (7%) Query: 28 SMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESA 87 S+ CP +R +VL KG+ + ++ + P+ P +P+L ++ Sbjct: 38 SVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAPGSQLPIL-LYDSDAKTDTL 96 Query: 88 ITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFR 147 ++L+E P + ++F K + + + + +Q++ Y L Sbjct: 97 QIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRALA 156 Query: 148 KEFTKL----------EEVLTNKKTTFFGGNSISMIDYLIWPWFERLE----AMKLNECV 193 + + L E L + F G+ +++ D + P ++ + Sbjct: 157 RLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCAHFRQAPIP 216 Query: 194 DHTPKLKLWMA-AMKEDPTVSALLTSEKDWQGF 225 ++ ++ AM+E S + + Sbjct: 217 AELRGVRRYLDSAMQEKEFKYTCPHSAEILAAY 249 >2VCT-A nrPDB Length = 222 Score = 82.5 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 40/189 (21%), Positives = 70/189 (37%), Gaps = 15/189 (7%) Query: 38 TRLVLKAKGIRHEVI----NINLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYL 93 R +L A G+ E +L + F VP++E +L+ ++ Y+ Sbjct: 19 IRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM--FQQVPMVEIDGMKLV-QTRAILNYI 75 Query: 94 DEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGL----KEEFRKE 149 Y L D EKA M +E + + ++ +Q +E A L ++ + Sbjct: 76 ASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQDAKLALIQEKTKNRY 132 Query: 150 FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKED 209 F E+VL + + GN +S D + +E + + P LK + Sbjct: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS-SLISSFPLLKALKTRISNL 191 Query: 210 PTVSALLTS 218 PTV L Sbjct: 192 PTVKKFLQP 200 >1PL2-A nrPDB Length = 222 Score = 82.5 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 40/190 (21%), Positives = 70/190 (36%), Gaps = 17/190 (8%) Query: 38 TRLVLKAKGIRHEVI----NINLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYL 93 TR +L A G+ E +L + F VP++E +L+ E Y+ Sbjct: 19 TRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM--FQQVPMVEIDGMKLVQE-RAILNYI 75 Query: 94 DEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAG----LKEEFR-K 148 Y L D E+A M +E + + ++ + E+ +KE+ + + Sbjct: 76 ASKY---NLYGKDIKERALIDMYIEGIADLGEMIL-LLPVCPPEEKDAKLALIKEKIKNR 131 Query: 149 EFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 F E+VL + + GN +S D + +E + + P LK + Sbjct: 132 YFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS-SLISSFPLLKALKTRISN 190 Query: 209 DPTVSALLTS 218 PTV L Sbjct: 191 LPTVKKFLQP 200 >1HNA-A nrPDB Length = 217 Score = 82.1 bits (201), Expect = 2e-16, Method: Composition-based stats. Identities = 37/200 (18%), Positives = 80/200 (40%), Gaps = 19/200 (9%) Query: 35 AERTRLVLKAKGIRHEVININLKNKP-----EWFFKKNPFGL----VPVLENSQGQLIYE 85 A RL+L+ +E + + P +W +K GL +P L + + I + Sbjct: 13 AHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHK-ITQ 71 Query: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE 145 S Y+ L + E+ + ++ F + D+ LK E Sbjct: 72 SNAILRYIARK---HNLCGESEKEQIREDILENQFMDS---RMQLAKLCYDPDFEKLKPE 125 Query: 146 FRKEFTKLEEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWM 203 + + ++ ++ + K +F G+ I+ +D++ + ER + + C+D P LK ++ Sbjct: 126 YLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEP-SCLDAFPNLKDFI 184 Query: 204 AAMKEDPTVSALLTSEKDWQ 223 + + +SA + S + Sbjct: 185 SRFEGLEKISAYMKSSRFLP 204 >2VCV-A nrPDB Length = 222 Score = 81.7 bits (200), Expect = 2e-16, Method: Composition-based stats. Identities = 37/198 (18%), Positives = 67/198 (33%), Gaps = 19/198 (9%) Query: 38 TRLVLKAKGIRHEVI----NINLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYL 93 R +L A G+ E +L F VP++E +L+ ++ Y+ Sbjct: 19 IRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLM--FQQVPMVEIDGMKLV-QTRAILNYI 75 Query: 94 DEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFR-----K 148 Y L D E+A M E + + ++ + E+ + + Sbjct: 76 ASKY---NLYGKDIKERALIDMYTEGMADLNEMIL-LLPLCRPEEKDAKIALIKEKTKSR 131 Query: 149 EFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 F E+VL + + GN +S D + +E + + + P LK + Sbjct: 132 YFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDS-SLISNFPLLKALKTRISN 190 Query: 209 DPTVSALLT--SEKDWQG 224 PTV L S + Sbjct: 191 LPTVKKFLQPGSPRKPPA 208 >2C3Q-A nrPDB Length = 247 Score = 81.3 bits (199), Expect = 4e-16, Method: Composition-based stats. Identities = 36/202 (17%), Positives = 59/202 (29%), Gaps = 21/202 (10%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININL---KNKPEWFFKKNPFGLVPVLENSQ 79 + +Y + K I E+ ++L ++ + F + NP VP L++ Sbjct: 9 GLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGD 68 Query: 80 GQLIYESAITCEYLDEAYPGKKL-LPDDPYEKACQKMILELFS------------KVPSL 126 + ES YL Y P D +A L Sbjct: 69 FT-LTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMF 127 Query: 127 VGSFIRSQNKEDYAGLKEEFRKEFTKLE-EVLTNKKTTFFGGNSISMIDYLIWPWFERLE 185 + + A E LE + L NK F G IS+ D + Sbjct: 128 PVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKA--FLTGPHISLADLVAITELMH-P 184 Query: 186 AMKLNECVDHTPKLKLWMAAMK 207 + + PKL W ++ Sbjct: 185 VGAGCQVFEGRPKLATWRQRVE 206 >3I6A-A nrPDB Length = 222 Score = 80.9 bits (198), Expect = 5e-16, Method: Composition-based stats. Identities = 39/190 (20%), Positives = 71/190 (37%), Gaps = 17/190 (8%) Query: 38 TRLVLKAKGIRHEVI----NINLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYL 93 TR +L A G+ E +L + F VP++E +L+ ++ Y+ Sbjct: 19 TRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM--FQQVPMVEIDGMKLV-QTRAILNYI 75 Query: 94 DEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAG----LKEEFR-K 148 Y L D E+A M +E + + ++ + E+ +KE+ + + Sbjct: 76 ASKY---NLYGKDIKERALIDMYIEGIADLGEMII-MLPFCPPEEKDAKLALIKEKIKNR 131 Query: 149 EFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 F E+VL + + GN +S D + +E + + P LK + Sbjct: 132 YFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS-SLISSFPLLKALKTRISN 190 Query: 209 DPTVSALLTS 218 PTV L Sbjct: 191 LPTVKKFLQP 200 >5LCZ-A nrPDB Length = 222 Score = 80.5 bits (197), Expect = 6e-16, Method: Composition-based stats. Identities = 36/199 (18%), Positives = 70/199 (35%), Gaps = 15/199 (7%) Query: 38 TRLVLKAKGIRHEVI----NINLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYL 93 TR +L A G+ E +L + F VP++E +L+ ++ Y+ Sbjct: 19 TRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM--FQQVPMVEIDGMKLV-QTRAILNYI 75 Query: 94 DEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFI--RSQNKEDYAGLKEEFRK--E 149 Y L D E+A M E + ++ + +E L ++ K Sbjct: 76 ASKY---NLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQREAKTALAKDRTKNRY 132 Query: 150 FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKED 209 E+VL + + GN ++ +D + +E + P LK + + + Sbjct: 133 LPAFEKVLKSHGQDYLVGNRLTRVDIHLLELLLYVEEFD-ASLLTSFPLLKAFKSRISSL 191 Query: 210 PTVSALLTSEKDWQGFLEL 228 P V L + ++ Sbjct: 192 PNVKKFLQPGSQRKPAMDA 210 >1B48-A nrPDB Length = 221 Score = 79.4 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 39/200 (19%), Positives = 68/200 (34%), Gaps = 11/200 (5%) Query: 25 RIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNP--FGLVPVLENSQGQL 82 ++Y E R +L A G+ E + + + E K FG VP L G + Sbjct: 5 KLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVP-LVEIDGMM 63 Query: 83 IYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAG- 141 + ++ YL Y L D E+ M + + ++ KE Sbjct: 64 LTQTRAILSYLAAKY---NLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESY 120 Query: 142 ---LKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPK 198 L + F E++L + F GN +S D + +E + + P Sbjct: 121 DLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELS-APVLSDFPL 179 Query: 199 LKLWMAAMKEDPTVSALLTS 218 L+ + + PT+ L Sbjct: 180 LQAFKTRISNIPTIKKFLQP 199 >1DUG-A nrPDB Length = 234 Score = 78.6 bits (192), Expect = 2e-15, Method: Composition-based stats. Identities = 32/177 (18%), Positives = 71/177 (40%), Gaps = 18/177 (10%) Query: 52 ININLKNKPEWFFKKNPFGL----VPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDP 107 +W KK GL +P + + + +S Y+ + +L P Sbjct: 30 HLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVK-LTQSMAIIRYIADK---HNMLGGCP 85 Query: 108 YEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNK--KTTFF 165 E+A M+ V + R +D+ LK +F + ++ ++ ++ T+ Sbjct: 86 KERAEISMLE---GAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYL 142 Query: 166 GGNSISMIDYLIWPWFERLEAMKLNE--CVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 G+ ++ D++++ + L+ + + C+D PKL + ++ P + L S K Sbjct: 143 NGDHVTHPDFMLY---DALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSK 196 >1B8X-A nrPDB Length = 280 Score = 78.2 bits (191), Expect = 3e-15, Method: Composition-based stats. Identities = 32/177 (18%), Positives = 71/177 (40%), Gaps = 18/177 (10%) Query: 52 ININLKNKPEWFFKKNPFGL----VPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDP 107 +W KK GL +P + + + +S Y+ + +L P Sbjct: 30 HLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVK-LTQSMAIIRYIADK---HNMLGGCP 85 Query: 108 YEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNK--KTTFF 165 E+A M+ V + R +D+ LK +F + ++ ++ ++ T+ Sbjct: 86 KERAEISMLE---GAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYL 142 Query: 166 GGNSISMIDYLIWPWFERLEAMKLNE--CVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 G+ ++ D++++ + L+ + + C+D PKL + ++ P + L S K Sbjct: 143 NGDHVTHPDFMLY---DALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSK 196 >1BG5-A nrPDB Length = 254 Score = 78.2 bits (191), Expect = 3e-15, Method: Composition-based stats. Identities = 32/177 (18%), Positives = 71/177 (40%), Gaps = 18/177 (10%) Query: 52 ININLKNKPEWFFKKNPFGL----VPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDP 107 +W KK GL +P + + + +S Y+ + +L P Sbjct: 31 HLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVK-LTQSMAIIRYIADK---HNMLGGCP 86 Query: 108 YEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNK--KTTFF 165 E+A M+ V + R +D+ LK +F + ++ ++ ++ T+ Sbjct: 87 KERAEISMLE---GAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYL 143 Query: 166 GGNSISMIDYLIWPWFERLEAMKLNE--CVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 G+ ++ D++++ + L+ + + C+D PKL + ++ P + L S K Sbjct: 144 NGDHVTHPDFMLY---DALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSK 197 >3GTU-B nrPDB Length = 224 Score = 77.5 bits (189), Expect = 5e-15, Method: Composition-based stats. Identities = 38/197 (19%), Positives = 80/197 (40%), Gaps = 19/197 (9%) Query: 35 AERTRLVLKAKGIRHEVINI-----NLKNKPEWFFKKNPFGL----VPVLENSQGQLIYE 85 A RL+L+ +E ++ +W K L +P L + + + I + Sbjct: 17 AHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNK-ITQ 75 Query: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE 145 S Y+ + + EK +I ++V IR D+ LK + Sbjct: 76 SNAILRYIARK---HNMCGETEEEKIRVDIIE---NQVMDFRTQLIRLCYSSDHEKLKPQ 129 Query: 146 FRKEF-TKLEEV-LTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWM 203 + +E +L++ + K ++F G ++ +D+L + ++ +C+D P LK +M Sbjct: 130 YLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDP-KCLDEFPNLKAFM 188 Query: 204 AAMKEDPTVSALLTSEK 220 + ++A L S++ Sbjct: 189 CRFEALEKIAAYLQSDQ 205 >1EV4-A nrPDB Length = 221 Score = 77.5 bits (189), Expect = 5e-15, Method: Composition-based stats. Identities = 36/192 (18%), Positives = 64/192 (33%), Gaps = 21/192 (10%) Query: 38 TRLVLKAKGIRHEVININLKNKPEWFFKKNPFG-----LVPVLENSQGQLIYESAITCEY 92 R +L A G+ + I PE K G VP++E + + ++ Y Sbjct: 18 IRFLLAAAGVEFDEKFI---QSPEDLEKLKKDGNLMFDQVPMVEIDGMK-LAQTRAILNY 73 Query: 93 LDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKE--- 149 + Y L D E+A M E + ++ + D K K+ Sbjct: 74 IATKYD---LYGKDMKERALIDMYSEGILDLTEMIMQLV--ICPPDQKEAKTALAKDRTK 128 Query: 150 ---FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAM 206 E+VL + + GN ++ +D + +E + P LK + + + Sbjct: 129 NRYLPAFEKVLKSHGQDYLVGNKLTRVDIHLLELLLYVEEFD-ASLLTSFPLLKAFKSRI 187 Query: 207 KEDPTVSALLTS 218 P V L Sbjct: 188 SSLPNVKKFLQP 199 >1XWK-A nrPDB Length = 218 Score = 75.9 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 39/202 (19%), Positives = 80/202 (39%), Gaps = 23/202 (11%) Query: 35 AERTRLVLKAKGIRHEVININLKNKP-----EWFFKKNPFGL----VPVLENSQGQLIYE 85 A RL+L+ +E + + P +W +K GL +P L + + I + Sbjct: 14 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHK-ITQ 72 Query: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE 145 S Y+ L + EK ++ ++ ++ LK + Sbjct: 73 SNAILCYIARK---HNLCGETEEEKIRVDILE---NQTMDNHMQLGMICYNPEFEKLKPK 126 Query: 146 FRKEF-TKLE---EVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKL 201 + +E KL+ E L + +F GN I+ +D+L++ + + +C+D P LK Sbjct: 127 YLEELPEKLKLYSEFLGKR--PWFAGNKITFVDFLVYDVLDLHRIFEP-KCLDAFPNLKD 183 Query: 202 WMAAMKEDPTVSALLTSEKDWQ 223 +++ + +SA + S + Sbjct: 184 FISRFEGLEKISAYMKSSRFLP 205 >1GUL-A nrPDB Length = 222 Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 37/189 (19%), Positives = 75/189 (39%), Gaps = 15/189 (7%) Query: 38 TRLVLKAKGIRHEVININLKNKPEWFFKKNPFG----LVPVLENSQGQLIYESAITCEYL 93 R VL A G+ + L+ K + + ++ VP++E +L+ ++ Y+ Sbjct: 19 VRWVLAAAGVEFD--EEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLV-QTRSILHYI 75 Query: 94 DEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVG--SFIR--SQNKEDYAGLKEEFRKE 149 + L + E+ M +E + L+ F++ Q KE ++ + Sbjct: 76 ADK---HNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRY 132 Query: 150 FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKED 209 F E++L +F GN +S+ D ++ LE K+ + P L+ + + Sbjct: 133 FPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEE-KIPNILSAFPFLQEYTVKLSNI 191 Query: 210 PTVSALLTS 218 PT+ L Sbjct: 192 PTIKRFLEP 200 >5D73-A nrPDB Length = 208 Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 42/196 (21%), Positives = 76/196 (38%), Gaps = 9/196 (4%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL 82 S ++ AE RLVL +GI+ IN + P + FG +P L + Q+ Sbjct: 2 SYKLTYFPIRGLAEPIRLVLVDQGIKFTDDRINASDWPSMKSHFH-FGQLPCLYDGDHQI 60 Query: 83 IYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNK-EDYAG 141 + +S +L L + E M E + + I E + Sbjct: 61 V-QSGAILRHLARK---HNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQAYDTEKDSY 116 Query: 142 LKEEFRKEFTKLEEVLTNKKT--TFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKL 199 +K+ E K E++L + F G IS +D++++ + + + C+D P L Sbjct: 117 IKDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDP-HCLDKFPLL 175 Query: 200 KLWMAAMKEDPTVSAL 215 K + M++ P + Sbjct: 176 KAYHQRMEDRPGLKEY 191 >5FWG-A nrPDB Length = 217 Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 38/194 (19%), Positives = 78/194 (40%), Gaps = 19/194 (9%) Query: 38 TRLVLKAKGIRHEVININLKNKP-----EWFFKKNPFGL----VPVLENSQGQLIYESAI 88 RL+L+ +E + + P +W +K GL +P L + + I +S Sbjct: 16 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRK-ITQSNA 74 Query: 89 TCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRK 148 YL L + E+ ++ ++V I D+ K EF K Sbjct: 75 IMRYLARK---HHLCGETEEERIRADIVE---NQVMDNRMQLIMLCYNPDFEKQKPEFLK 128 Query: 149 EFTKLEEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAM 206 + ++ + K +F G+ ++ +D+L + ++ + +C+D P LK ++A Sbjct: 129 TIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEP-KCLDAFPNLKDFLARF 187 Query: 207 KEDPTVSALLTSEK 220 + +SA + S + Sbjct: 188 EGLKKISAYMKSSR 201 >1YQ1-A nrPDB Length = 208 Score = 74.8 bits (182), Expect = 3e-14, Method: Composition-based stats. Identities = 39/203 (19%), Positives = 67/203 (33%), Gaps = 14/203 (6%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL 82 S ++ F E RL+ G++ E + +N P +PVL G Sbjct: 3 SYKLTYFFFRGLGEPIRLLFHLAGVQFEEVRMNPDQTWLDIKDSTPMKQLPVLNI-DGFE 61 Query: 83 IYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGL 142 + +S YL + P E+A + +LF + F + A Sbjct: 62 LPQSGAILRYLARKF---GFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSGKSAEE 118 Query: 143 KEEFRKE---------FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECV 193 E+FR E F L +L + F G+ I+ D ++ L+ L + Sbjct: 119 VEKFRSEFFLPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKNYGLFD-E 177 Query: 194 DHTPKLKLWMAAMKEDPTVSALL 216 KL + P + + Sbjct: 178 SEFTKLAALREKVNSYPGIKEYI 200 >4FQU-A nrPDB Length = 313 Score = 74.4 bits (181), Expect = 4e-14, Method: Composition-based stats. Identities = 43/258 (16%), Positives = 88/258 (34%), Gaps = 47/258 (18%) Query: 20 PEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP------------------- 60 G +Y+ CP+A R ++ KG+ E+I++++ N Sbjct: 41 EPGRYHLYAGFACPWAHRVLIMRALKGLE-EMISVSMVNAYMGENGWTFLPGDDVVPDSI 99 Query: 61 -------EWFFKKNP----FGLVPVLENSQGQLI--YESAITCEYLDEAYPGKKLLPDDP 107 + + +P +P+L + + I ES+ L+ A+ LP D Sbjct: 100 NGADYLYQVYTAADPTYTGRVTIPILWDKVEKRILNNESSEIIRILNSAFDDVGALPGD- 158 Query: 108 YEKACQKMILELFSKVPS--LVGSFIRSQNKEDYAGLKEE---FRKEFTKLEEVLTNKKT 162 Y A + ++ + L RS +E LEE LT ++ Sbjct: 159 YYPAEFRPEIDRINARVYETLNNGVYRSGFATTQEAYEEAFYPLFDTLDWLEEHLTGRE- 217 Query: 163 TFFGGNSISMIDYLIWPWFERLEAM--KLNEC----VDHTPKLKLWMAAMKEDPTVSALL 216 + G+ ++ D ++P R +A+ +C + P L + + V+ + Sbjct: 218 -WLVGDRLTEADIRLFPTLVRFDAIYHGHFKCNLRRIADYPNLSRLVGKLASHERVAPTI 276 Query: 217 TSEKDWQGFLELYLQNSP 234 + + +P Sbjct: 277 NLRHAKAHYYGSHPSVNP 294 >5AN1-A nrPDB Length = 219 Score = 74.4 bits (181), Expect = 4e-14, Method: Composition-based stats. Identities = 36/200 (18%), Positives = 73/200 (36%), Gaps = 19/200 (9%) Query: 35 AERTRLVLKAKGIRHEVININL-----KNKPEWFFKKNPFGL----VPVLENSQGQLIYE 85 + RL+L G E N + +K EW K GL +P + + I + Sbjct: 14 CQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPYYIDGDVK-ITQ 72 Query: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE 145 S YL L P E MI + + + + ++ E Sbjct: 73 SKAIMRYLARK---HGLCGTTPEELVRTDMIECQLTDMHEAFFT-VTYEHYEQKDAYTAS 128 Query: 146 FRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNE-CVDHTPKLKLWMA 204 + + + L ++ +F G+ ++ ID+L + F+ + + L+ C+D L+ + Sbjct: 129 LPAKLRQYSDFLGSR--PWFAGDKLTYIDFLAYEIFD--QHLSLDRTCLDGFKNLQAFQK 184 Query: 205 AMKEDPTVSALLTSEKDWQG 224 ++ + + S K + Sbjct: 185 RFEDLEAIKKYMASPKFLKK 204 >1B4P-A nrPDB Length = 217 Score = 73.2 bits (178), Expect = 9e-14, Method: Composition-based stats. Identities = 37/208 (17%), Positives = 80/208 (38%), Gaps = 21/208 (10%) Query: 38 TRLVLKAKGIRHEVININLKNKP-----EWFFKKNPFGL----VPVLENSQGQLIYESAI 88 RL+L+ +E + + P +W +K GL +P L + + I +S Sbjct: 16 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRK-ITQSNA 74 Query: 89 TCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRK 148 YL L + E+ ++ ++ D+ K E+ + Sbjct: 75 IMRYLARK---HHLCGETEEERIRVDVLE---NQAMDTRLQLAMVCYSPDFERKKPEYLE 128 Query: 149 EFTKLEEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAM 206 + ++ + K +F GN I+ +D+L++ ++ + +C+D P LK ++A Sbjct: 129 GLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQHRIFEP-KCLDAFPNLKDFVARF 187 Query: 207 KEDPTVSALLTSEKDWQG--FLELYLQN 232 + +S + S + F ++ N Sbjct: 188 EGLKKISDYMKSGRFLSKPIFAKMAFWN 215 >4Q5R-A nrPDB Length = 204 Score = 73.2 bits (178), Expect = 9e-14, Method: Composition-based stats. Identities = 39/195 (20%), Positives = 70/195 (35%), Gaps = 12/195 (6%) Query: 27 YSMRFCP---FAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLI 83 Y + +CP E R +L E + P PFG PVLE G+ Sbjct: 5 YKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSM-PFGKTPVLEI-DGKQT 62 Query: 84 YESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAG-- 141 ++S YL + + L D +E MI++ S + + ++ ++ Sbjct: 63 HQSVAISRYLGKQF---GLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQKKW 119 Query: 142 --LKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKL 199 LK+E +TK + + + ++ D+ + L M + V + P L Sbjct: 120 DPLKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQPNL 179 Query: 200 KLWMAAMKEDPTVSA 214 K + P + A Sbjct: 180 KALREKVLGLPAIKA 194 >4Q5F-A nrPDB Length = 218 Score = 73.2 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 42/195 (21%), Positives = 77/195 (39%), Gaps = 16/195 (8%) Query: 38 TRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAY 97 RL+ G++ E + ++ P K PFG +P+LE G+++ +SA YL + Sbjct: 30 ARLIFHQAGVKFEDNRLKREDWPA-LKPKTPFGQLPLLEV-DGEVLAQSAAIYRYLGRQF 87 Query: 98 PGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKE-------- 149 L P E+A I + F + + R + G KE+ KE Sbjct: 88 ---GLAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFE-EGDKEKVLKEVAVPARDK 143 Query: 150 -FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 LE+ L + + G S++ D +I E++ + H +LK ++ ++E Sbjct: 144 HLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDFLSGHL-QLKKYIEHVRE 202 Query: 209 DPTVSALLTSEKDWQ 223 P + + Sbjct: 203 LPNIKKWIAERPKTP 217 >2AAW-A nrPDB Length = 222 Score = 71.3 bits (173), Expect = 3e-13, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 78/214 (36%), Gaps = 20/214 (9%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKN-------PFGLVP 73 +I +Y AE RL+ GI + + N + KN PF VP Sbjct: 13 GDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGV-NGDAFVEFKNFKKEKDTPFEQVP 71 Query: 74 VLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRS 133 +L+ ++ +S YL + Y + + + MI + + Sbjct: 72 ILQIGDL-ILAQSQAIVRYLSKKY---NICGESELNEFYADMIFCGVQDIHYKFNN-TNL 126 Query: 134 QNKEDYAGLKEEFRKEFTKLEEVLTNKKT------TFFGGNSISMIDYLIWPWFERLEAM 187 + + L E+ K E++L T +F GN+++ D ++ ++ +E Sbjct: 127 FKQNETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIET- 185 Query: 188 KLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKD 221 K + + P LK + P + +T+ K+ Sbjct: 186 KYPSSLKNFPLLKAHNEFISNLPNIKNYITNRKE 219 >1GSQ-A nrPDB Length = 202 Score = 70.1 bits (170), Expect = 8e-13, Method: Composition-based stats. Identities = 43/201 (21%), Positives = 69/201 (34%), Gaps = 13/201 (6%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL 82 ++ AE R VL A G + + + P +PVL + G Sbjct: 2 KYTLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMY-SNAMPVL-DIDGTK 59 Query: 83 IYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGS--FIRSQNKEDYA 140 + +S +L + L EK I E + + V F KE Sbjct: 60 MSQSMCIARHLAREF---GLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKEAVQ 116 Query: 141 GLKEEFRKEFT-KLEEVLTNKKTT--FFGGNSISMIDYLIWPWFER-LEAMKLNECVDHT 196 E+ K LE +L + FF GNS+++ D + E L+ E + Sbjct: 117 QNYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTP--ELLKDC 174 Query: 197 PKLKLWMAAMKEDPTVSALLT 217 PK+ + E P ++A L Sbjct: 175 PKIVALRKRVAECPKIAAYLK 195 >4WR5-A nrPDB Length = 244 Score = 69.7 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 67/170 (39%), Gaps = 14/170 (8%) Query: 57 KNKPEWFFKKNPFGL----VPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKAC 112 +W KK GL +P + + + +S + + +L P E+A Sbjct: 60 DEGDKWRNKKFELGLEFPNLPYXIDGDVK-LTQSMAIIRXIADK---HNMLGGCPKERAE 115 Query: 113 QKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNK--KTTFFGGNSI 170 M+ V + R +D+ LK +F + ++ ++ ++ T G+ + Sbjct: 116 ISMLE---GAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTXLNGDHV 172 Query: 171 SMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 + D++++ + + M C+D PKL + ++ P + L S K Sbjct: 173 THPDFMLYDALDVVLXMDPM-CLDAFPKLVCFKKRIEAIPQIDKYLKSSK 221 >3PPU-A nrPDB Length = 352 Score = 68.6 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 42/238 (17%), Positives = 77/238 (32%), Gaps = 54/238 (22%) Query: 19 VPEGSIRIYSMRFCPFAERTRLVLKAKGIR----------------HEVININLKNK--- 59 +G +Y CP+A RT +V K KG+ N++ Sbjct: 73 PEKGRYHLYVSYACPWATRTLIVRKLKGLEDFIGVTVVSPRMGSNGWPFANVDPFPAADS 132 Query: 60 ---------PEWFFKKNP----FGLVPVLENSQGQLIY--ESAITCEYLDEAYPGKKLLP 104 + + K P VPVL + I ES+ + A+ LLP Sbjct: 133 DPLNNAQHVKDLYLKVKPDYDGRFTVPVLWDKHTGTIVNNESSEIIRMFNTAFNH--LLP 190 Query: 105 DDPYE--------KACQKMILEL-FSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEE 155 +D + +A + + + V + V + ++ Y + +LE+ Sbjct: 191 EDKAKLDLYPESLRAKIDEVNDWVYDTVNNGVYKSGFASTQKAYEAAVIPLFESLDRLEK 250 Query: 156 VLTNKKTTFFGGNSISMIDYLIWPWFERLE-------AMKLNECVDHTPKLKLWMAAM 206 +L + + G ++ D ++ R + L D P L WM + Sbjct: 251 MLEGQD--YLIGGQLTEADIRLFVTIVRFDPVYVTHFKCNLRTIRDGYPNLHRWMRKL 306 >2GLR-A nrPDB Length = 209 Score = 68.2 bits (165), Expect = 3e-12, Method: Composition-based stats. Identities = 36/192 (18%), Positives = 71/192 (36%), Gaps = 16/192 (8%) Query: 35 AERTRLVLKAKGIRHEVININLKN----KPEWFFKKNPFGLVPVLENSQGQLIYESAITC 90 A R L + + + EV+ I+ KP +G +P E+ +Y+S Sbjct: 16 AMRMLLADQGQSWKEEVVTIDTWMQGLLKPTCL-----YGQLPKFEDGDLT-LYQSNAIL 69 Query: 91 EYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEF 150 +L + L + E A M+ + + + I + + + Sbjct: 70 RHLGRSL---GLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYENGKNDYVKALPGHL 126 Query: 151 TKLEEVLTNKKTT--FFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 E +L+ + F G+ IS DY + + + C+D+ P L ++A + Sbjct: 127 KPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPG-CLDNFPLLSAYVARLSA 185 Query: 209 DPTVSALLTSEK 220 P + A L+S + Sbjct: 186 RPKIKAFLSSPE 197 >3BBY-A nrPDB Length = 215 Score = 67.8 bits (164), Expect = 4e-12, Method: Composition-based stats. Identities = 32/163 (19%), Positives = 61/163 (37%), Gaps = 14/163 (8%) Query: 28 SMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGL---VPVLENSQGQLIY 84 + F P+ + L+ KG+ + I+L + +G VP+L+ + + Sbjct: 13 AHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTWQGYGQTRRVPLLQIDDFE-LS 71 Query: 85 ESAITCEYLDEAYPGK---KLLPDDPYEKACQKMILELF-SKVPSLVGS------FIRSQ 134 ES+ EYL++ + ++ P D +A + I S + + F ++ Sbjct: 72 ESSAIAEYLEDRFAPPTWERIYPLDLENRARARQIQAWLRSDLMPIREERPTDVVFAGAK 131 Query: 135 NKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLI 177 A K K F E +L + FG I+ D + Sbjct: 132 KAPLTAEGKASAEKLFAMAEHLLVLGQPNLFGEWCIADTDLAL 174 >1GSU-A nrPDB Length = 219 Score = 67.4 bits (163), Expect = 5e-12, Method: Composition-based stats. Identities = 32/203 (15%), Positives = 76/203 (37%), Gaps = 23/203 (11%) Query: 35 AERTRLVLKAKGIRHEVININLKNKPE-----WFFKKNPFGL----VPVLENSQGQLIYE 85 A RL+L+ ++ P+ W +K GL +P L + + + + Sbjct: 13 AHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPYLIDGDVK-LTQ 71 Query: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE 145 S Y+ + + EK ++ + + L +F R D+ LK Sbjct: 72 SNAILRYIARK---HNMCGETEVEKQRVDVLE---NHLMDLRMAFARLCYSPDFEKLKPA 125 Query: 146 FRKEFT----KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKL 201 + ++ +L L ++ +F G+ ++ +D+L + ++ +C + L Sbjct: 126 YLEQLPGKLRQLSRFLGSRS--WFVGDKLTFVDFLAYDVLDQQRMFVP-DCPELQGNLSQ 182 Query: 202 WMAAMKEDPTVSALLTSEKDWQG 224 ++ + +SA + S + + Sbjct: 183 FLQRFEALEKISAYMRSGRFMKA 205 >5F8B-A nrPDB Length = 244 Score = 67.4 bits (163), Expect = 5e-12, Method: Composition-based stats. Identities = 31/197 (15%), Positives = 59/197 (29%), Gaps = 16/197 (8%) Query: 46 GIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPD 105 G+ ++ + + G VP + + ++E Y+ LL Sbjct: 27 GLDLDIRE---TPRTPDHLSISKLGKVPAFQGADSFKLFECMAIALYITSQNEQTTLLGK 83 Query: 106 DPYEKACQKMILELFSK------VPSLVGSFIRSQNKEDY-AGLKEEFRKEFTKLEEVLT 158 D E A + F+ L+ D ++ +EE L Sbjct: 84 DKKEYAEIIKWMSFFNTEIVILMTQQLLPQLGVIPYDRDQVEFFANMTQRSVDVVEEYLQ 143 Query: 159 NKKTTFFGGNSISMIDYLIWPWFE-RLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLT 217 ++ TF G+ +S+ D + P + W + P +A+ Sbjct: 144 DR--TFLVGDQLSLADLFCAGNISLGFQFFYGKAWRQQNPNVSRWYEMVCHQPIYAAVTD 201 Query: 218 SEKDWQGFLELYLQNSP 234 +Q E L N+P Sbjct: 202 ---KFQLLDEPKLTNNP 215 >4G0L-A nrPDB Length = 328 Score = 67.0 bits (162), Expect = 7e-12, Method: Composition-based stats. Identities = 43/258 (16%), Positives = 88/258 (34%), Gaps = 44/258 (17%) Query: 19 VPEGSIRIYSMRFCPFAERTRLVLKAKGIR--------HEVININLKNKP---------- 60 + +Y CP+A RT ++ K KG+ + ++ N Sbjct: 50 AEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDT 109 Query: 61 --------EWFFKKNP----FGLVPVLENSQGQLIY--ESAITCEYLDEAYPGKKLLPDD 106 + + +P VPVL + + I ESA + A+ D Sbjct: 110 LYQNEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGD 169 Query: 107 PYEKACQKMILEL----FSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKT 162 Y A Q I EL + V + V + ++E Y + + +LE++L Sbjct: 170 YYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQH-- 227 Query: 163 TFFGGNSISMIDYLIWPWFERLE-----AMKLNE-CVDHTPKLKLWMAAMKEDPTVSALL 216 + GN ++ D +W R + K ++ + L ++ + + P ++ + Sbjct: 228 RYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETV 287 Query: 217 TSEKDWQGFLELYLQNSP 234 + + + +P Sbjct: 288 NFDHIRNHYFRSHKTINP 305 >18GS-A nrPDB Length = 210 Score = 65.9 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 58/157 (36%), Gaps = 15/157 (9%) Query: 70 GLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGS 129 G +P ++ +Y+S +L L D E A M + V L Sbjct: 51 GQLPKFQDGDLT-LYQSNTILRHLGRTL---GLYGKDQQEAALVDM---VNDGVEDLRCK 103 Query: 130 FIRSQNKEDYAGLKEEFRKEF----TKLEEVLTNKKT--TFFGGNSISMIDYLIWPWFER 183 +I +Y K+++ K E +L+ + TF G+ IS DY + Sbjct: 104 YISLIY-TNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLI 162 Query: 184 LEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220 E + C+D P L ++ + P + A L S + Sbjct: 163 HEVLAPG-CLDAFPLLSAYVGRLSARPKLKAFLASPE 198 >4Q5Q-A nrPDB Length = 219 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 36/198 (18%), Positives = 80/198 (40%), Gaps = 19/198 (9%) Query: 34 FAERTRLVLKAKGIRHEVININL-----KNKPEWFFKKNPFGL----VPVLENSQGQLIY 84 +A+ RL+L G+ + ++ EW +K GL +P + + + Sbjct: 14 YAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLPYYIDGDMK-MT 72 Query: 85 ESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKE 144 ++ YL Y KL + +E+ M + + ++ + IR + LK Sbjct: 73 QTFAILRYLGRKY---KLNGSNDHEEIRISMAEQ---QTEDMMAAMIRVCYDANCDKLKP 126 Query: 145 EFRKEFTKLEEVLTN--KKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLW 202 ++ K ++++ + F G +IS +D+ ++ + ++ M E LK + Sbjct: 127 DYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCHVKVMVP-EVFGQFENLKRY 185 Query: 203 MAAMKEDPTVSALLTSEK 220 + M+ P VS + ++ Sbjct: 186 VERMESLPRVSDYIKKQQ 203 >1TU7-A nrPDB Length = 208 Score = 64.0 bits (154), Expect = 6e-11, Method: Composition-based stats. Identities = 41/199 (20%), Positives = 73/199 (36%), Gaps = 15/199 (7%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKK---NPFGLVPVLENSQ 79 S ++ AE RL L + I+ I+ + + F FG +P L + Sbjct: 2 SYKLTYFSIRGLAEPIRLFLVDQDIKF----IDDRIAKDDFSSIKSQFQFGQLPCLYDGD 57 Query: 80 GQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNK-ED 138 Q++ +S +L Y L ++ E M E + I + E Sbjct: 58 QQIV-QSGAILRHLARKY---NLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMAYETEK 113 Query: 139 YAGLKEEFRKEFTKLEEVLTNKKT--TFFGGNSISMIDYLIWPWFERLEAMKLNECVDHT 196 +K E K E++L + G+ IS DY ++ + + + C+D Sbjct: 114 DPYIKSILPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDP-HCLDKF 172 Query: 197 PKLKLWMAAMKEDPTVSAL 215 P LK++ MK+ P + Sbjct: 173 PLLKVFHQRMKDRPKLKEY 191 >1ZL9-A nrPDB Length = 207 Score = 63.6 bits (153), Expect = 8e-11, Method: Composition-based stats. Identities = 36/198 (18%), Positives = 69/198 (34%), Gaps = 21/198 (10%) Query: 39 RLVLKAKGIRHEVININLKNKPEWFFKK----NPFGLVPVLENSQGQLIYESAITCEYLD 94 R + G ++E + + +W K PFG +P LE G+ + +S +L Sbjct: 19 RQIFAYAGQQYEDNRV---TQEQWPALKETCAAPFGQLPFLEV-DGKKLAQSHAIARFLA 74 Query: 95 EAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSF---IRSQNKEDYAGLKE-----EF 146 + KL +E+A + + + S + + D LK+ F Sbjct: 75 REF---KLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMGFGPGDVETLKKDIFLPAF 131 Query: 147 RKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAM 206 K + L L + F G+S++ ID I + + P+LK + Sbjct: 132 EKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQ--HSADLIAKGGDFSKFPELKAHAEKI 189 Query: 207 KEDPTVSALLTSEKDWQG 224 + P + + + Sbjct: 190 QAIPQIKKWIETRPVTPF 207 >6GCB-A nrPDB Length = 325 Score = 62.8 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 47/239 (19%), Positives = 86/239 (35%), Gaps = 56/239 (23%) Query: 19 VPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVINI----NLKNKPEW-FFKKNPFG--- 70 +G +Y CP+A RT +V K KG+ E++ + L + W F +PF Sbjct: 43 PEKGRYHLYVAYSCPWATRTLIVRKIKGLE-EIVGVTIVSPLFSAHGWPFGDVSPFPGAE 101 Query: 71 -------------------------LVPVLENSQGQLIY--ESAITCEYLDEAYPGKKLL 103 VPVL + + + + ES+ + A+ L Sbjct: 102 ADPFYNAQYVRDLYLRADPKYEGRFTVPVLWDKKTETVVNNESSEIIRIFNTAFNE--FL 159 Query: 104 PDD-----PYEKACQKMILEL----FSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLE 154 P D Y +A + I E+ + V + V + ++ Y + +LE Sbjct: 160 PADKAAIHLYPEALKSEIDEINEWVYDTVNNGVYKAGFATTQQAYEAAVIPLFESLDRLE 219 Query: 155 EVLTNKKTTFFGGNSISMIDYLIWPWFERLE-------AMKLNECVDHTPKLKLWMAAM 206 ++LT K + G+ ++ D ++ R + L D P + LW+ + Sbjct: 220 KILTGKD--YLVGDQLTEADVRLFVTIIRFDPAYVGHFKCNLRTIRDGYPAIHLWLRKL 276 >4BVY-B nrPDB Length = 186 Score = 62.8 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 50/148 (33%), Gaps = 15/148 (10%) Query: 71 LVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSF 130 +PVL+ + G + +L + + LL EKA + LE Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEY----------- 89 Query: 131 IRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLN 190 + D K + L L +K + G + ++ D L++ R Sbjct: 90 --RVTQVDGHSSKNDIHTLLKDLNSYLEDK--VYLTGYNFTLADILLYYGLHRFIVDLTV 145 Query: 191 ECVDHTPKLKLWMAAMKEDPTVSALLTS 218 + + + W + ++ P + L+S Sbjct: 146 QEKEKYLNVSRWFSHIQHYPGIRQHLSS 173 >1U3I-A nrPDB Length = 211 Score = 62.4 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 28/209 (13%), Positives = 74/209 (35%), Gaps = 15/209 (7%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVL----E 76 I++ AE R+ L A G+ +E I+ ++ P+ P G +P + + Sbjct: 3 GEHIKVIYFDGRGRAESIRMTLVAAGVDYEDERISFQDWPKIKPTI-PGGRLPAVKVTDD 61 Query: 77 NSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNK 136 + + + ES Y+ + ++ + E + ++ V + + + Sbjct: 62 HGHVKWMLESLAIARYMAKK---HHMMGETDEEYYSVEKLIGQAEDVEHEYHKTL-MKPQ 117 Query: 137 EDYAGLKEEFRKE-----FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNE 191 E+ + +E F + E L G+ +++ D ++ + + + Sbjct: 118 EEKEKITKEILNGKVPVLFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGF 177 Query: 192 CVDHTPKLKLWMAA-MKEDPTVSALLTSE 219 P++ + P ++ L++ Sbjct: 178 LTGKYPEIHKHRENLLASSPRLAKYLSNR 206 >3KXO-A nrPDB Length = 202 Score = 62.0 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 34/181 (18%), Positives = 65/181 (35%), Gaps = 15/181 (8%) Query: 38 TRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAY 97 R + I++E I + PE PFG +P+LE G +++S YL Sbjct: 21 IRYIFAYLDIQYEDHRIEQADWPEIKSTL-PFGKIPILEV-DGLTLHQSLAIARYL---T 75 Query: 98 PGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFR-----KEFTK 152 L + E+ I++ S + ++ + E Sbjct: 76 KNTDLAGNTEMEQCHVDAIVDTLDDFMSCFP--WAEKKQDVKEQMFNELLTYNAPHLMQD 133 Query: 153 LEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTV 212 L+ L ++ + GNS++ D+ L K + +D+ P+L ++ P V Sbjct: 134 LDTYLGGRE--WLIGNSVTWADFYWEICSTTLLVFKP-DLLDNHPRLVTLRKKVQAIPAV 190 Query: 213 S 213 + Sbjct: 191 A 191 >2WDU-A nrPDB Length = 211 Score = 61.3 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 37/211 (17%), Positives = 71/211 (33%), Gaps = 13/211 (6%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLE----NS 78 +++ +F AE RL+L G++ E + P P G VP+L+ + Sbjct: 5 HFKLWYFQFRGRAEPIRLLLTCAGVKFEDYQFTMDQWPTIKPTL-PGGRVPLLDVTGPDG 63 Query: 79 QGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKED 138 + + ES L + K++ + E + I+ + V + R+ E Sbjct: 64 KLRRYQESMAIARLLARQF---KMMGETDEEYYLIERIIGECEDLYREVYTIFRTPQGEK 120 Query: 139 YAGLKE----EFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVD 194 A +KE + E L + GN I++ D ++ + Sbjct: 121 EAKIKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVMETVPGFLEQ 180 Query: 195 HTPKLKLWMAAM-KEDPTVSALLTSEKDWQG 224 PKL + ++ +S L Sbjct: 181 KFPKLHEFHKSLPTSCSRLSEYLKKRAKTPF 211 >5Y9Z-A nrPDB Length = 199 Score = 60.9 bits (146), Expect = 5e-10, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 67/180 (37%), Gaps = 11/180 (6%) Query: 38 TRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAY 97 R + I++E I + P+ PFG +PVLE G +++S YL Sbjct: 18 IRYIFAYLDIKYEDHRIEQADWPKIKPTL-PFGKIPVLEVE-GLTLHQSLAIARYL---T 72 Query: 98 PGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAG---LKEEFRKEFTKLE 154 L E+ +++ SL +Q+ ++ L + L+ Sbjct: 73 KNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWAEENQDLKERTFNDLLTRQAPHLLKDLD 132 Query: 155 EVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSA 214 L +K+ +F GN ++ D+ W + + + P+L ++ P +SA Sbjct: 133 TYLGDKE--WFIGNYVTWADF-YWDICSTTLLVLKPDLLGIYPRLVSLRNKVQAIPAISA 189 >6GC9-A nrPDB Length = 327 Score = 60.5 bits (145), Expect = 6e-10, Method: Composition-based stats. Identities = 42/242 (17%), Positives = 84/242 (34%), Gaps = 62/242 (25%) Query: 19 VPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK------------------- 59 +G +Y CP+A RT +V K KG+ E I++++ + Sbjct: 44 PEKGRYHLYVSYACPWATRTLIVRKIKGLE-EFIDVSVVSPRMGAHGWPFANVDAFPGAD 102 Query: 60 ----------PEWFFKKNP----FGLVPVLENSQGQLIY--ESAITCEYLDEAYPGKKLL 103 + + + NP VP+L + + I ES+ + A+ + L Sbjct: 103 ADPLFGAEHVKDLYMRVNPDYEGRFTVPILWDKKTSAIVNNESSEIIRMFNTAFNDQ--L 160 Query: 104 PDDPYEKACQKMILELFSKVPSLVGSFI------------RSQNKEDYAGLKEEFRKEFT 151 P D KA + E + ++ + +++ Y + Sbjct: 161 PSD---KAAIDLYPEALRGEIDGINEWVYDTVNNGVYKSGFATSQKAYEAAVVPLFESLD 217 Query: 152 KLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLE-------AMKLNECVDHTPKLKLWMA 204 +LE++LT K + G+ ++ D ++ R + + D P + LWM Sbjct: 218 RLEKILTGKD--YLVGDQLTEADIRLFVTIVRFDPVYVGHFKCNIRTIRDGYPAIDLWMR 275 Query: 205 AM 206 + Sbjct: 276 KL 277 >2CA8-A nrPDB Length = 211 Score = 60.5 bits (145), Expect = 6e-10, Method: Composition-based stats. Identities = 27/213 (12%), Positives = 70/213 (32%), Gaps = 13/213 (6%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQG 80 I++ AE R+ L A G+ +E I+ ++ P+ P G +P ++ + Sbjct: 3 GDHIKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTI-PGGRLPAVKITDN 61 Query: 81 ----QLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNK 136 + + ES Y+ + ++ E + ++ + + + Sbjct: 62 HGHVKWMVESLAIARYMAKK---HHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEE 118 Query: 137 EDYAGLKE----EFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNEC 192 E +KE + + E L G+ +++ D ++ + + + Sbjct: 119 EKQKIIKEILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFL 178 Query: 193 VDHTPKLKLWMAA-MKEDPTVSALLTSEKDWQG 224 P++ + P ++ L+ Sbjct: 179 TGKYPEIHKHRENLLASSPRLAKYLSDRAATPF 211 >6GZF-A nrPDB Length = 341 Score = 60.1 bits (144), Expect = 9e-10, Method: Composition-based stats. Identities = 34/259 (13%), Positives = 81/259 (31%), Gaps = 44/259 (16%) Query: 19 VPEGSIRIYSMRFCPFAERTRLVLKAKGIRH--EVININLKNKP---------------- 60 G +Y CP+A RT + KG+ V ++ Sbjct: 51 PEAGRYHLYVSYACPWAHRTLVTRTLKGLEDAISVSVVDPYRAEDGWQFTPEKEGCTHDH 110 Query: 61 --------EWFFKKNP----FGLVPVLENSQGQLIY--ESAITCEYLDEAYPGKKLLPDD 106 E + + P VPVL +++ I ES D + D Sbjct: 111 VHDVDYLRELYVRAAPDVTCRVTVPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVD 170 Query: 107 PYEKACQKMILELFSKV-PSLVGSFIRSQNKEDYAGLKEEFRKEFTKL---EEVLTNKKT 162 Y + Q+ + ++ + + R+ + E + F L ++VL ++ Sbjct: 171 LYPEGYQEKVDQIIDNIYEPINNGVYRAGFATEQEPYDEAVAELFGALAHWDDVLADQ-- 228 Query: 163 TFFGGNSISMIDYLIWPWFERLEAMKLNECV------DHTPKLKLWMAAMKEDPTVSALL 216 + G+ ++ D ++ R + + + L ++ + + ++ + Sbjct: 229 RYLAGDRLTEADIAMFTTLVRFDNVYHTHFMCNVQYIREFDNLWPYLRDLYQTHGIAETV 288 Query: 217 TSEKDWQGFLELYLQNSPE 235 + + + + +P Sbjct: 289 EMDHITEHYYTTHPDVNPH 307 >4LMW-A nrPDB Length = 251 Score = 59.7 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 40/220 (18%), Positives = 81/220 (36%), Gaps = 44/220 (20%) Query: 33 PFAERTRLVLKAKGIRHEVININLKNKPE-------WFFKKNPFG----LVPVLENSQGQ 81 P +TR VL KG+++ + + +K P G +PV+++ + Sbjct: 23 PNTWKTRYVLNFKGLKYRTEWVEYPDIEAVCKQIGAPATEKKPDGRDHYTLPVIQDPNTK 82 Query: 82 -LIYESAITCEYLDEAYPG-KKLLPDDP-------YEKACQKMILELFSKVPSLVGSFIR 132 ++ +S +YL+ YP +L P+ Y+ A +++ +F+ V + V +R Sbjct: 83 AVVADSDAIAKYLESTYPDTPRLFPEGTRAFQHAFYQLARPSVLMPIFNIVVARVWKLLR 142 Query: 133 SQNKEDYAGLKEEFR----------KEFTKLEEVLTN----------KKTTFFGGNSISM 172 +++E + +E+ ++ LE L K G+ ++ Sbjct: 143 PRSQEYFRATREQMLGKKLEEIGSEDDWNALESGLARIKSSLEANGAGKDLLLMGDRVTF 202 Query: 173 IDYLIWPWFERLEAMKLNECVD--HTPKLKL--WMAAMKE 208 D + F L E D L W M++ Sbjct: 203 ADLQLASLFIWLRVSAGEESEDWKRFLSLHEGKWAKFMQQ 242 >4USS-A nrPDB Length = 325 Score = 59.7 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 43/278 (15%), Positives = 85/278 (30%), Gaps = 61/278 (21%) Query: 18 PVPEGSIRIYSMRFCPFAERTRLVLKAKGIR-----HEVININLKNKPEW---------- 62 P G +Y CP+A R LK KG+ V I + K Sbjct: 35 PPESGRYHLYVSYACPWASRCLAYLKIKGLEKAIAFTSVKPIWERTKESDEHMGWVFPAS 94 Query: 63 -----------------------FFKKNPFGL--VPVLENSQGQLIY--ESAITCEYLDE 95 N G VPVL + + + I ES+ + Sbjct: 95 ETEEAGAEPDTLNGARSIRELYELASTNYAGKYTVPVLWDKKLKTIVNNESSEIIRMFNT 154 Query: 96 AYPGKK------LLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKE 149 + L P + + ++ + + V ++ + Y + + Sbjct: 155 EFNDIAENAALDLYPSHLQAQIDETNGW-VYDGINNGVYKCGFARKQGPYEEAAIQLYEA 213 Query: 150 FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAM------KLNECVDHTPKLKLWM 203 K EE+L + + GN++S D ++ R + + + + P + + Sbjct: 214 LDKCEEILGRQ--RYICGNTLSEADIKLFVTLIRFDEVYAVHFKCNKKLLRDYPNMFNYT 271 Query: 204 AAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL 241 + + P +S+ + Q Y + P +G+ Sbjct: 272 KDIFQIPGMSSTVN----MQHIKRHYYGSHPTVNPFGI 305 >1G7O-A nrPDB Length = 215 Score = 58.2 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 32/216 (14%), Positives = 72/216 (33%), Gaps = 36/216 (16%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLI 83 +++Y CP+ + R++ K I E+ ++ L + E + VP+L+ + + Sbjct: 1 MKLYIYDHCPYCLKARMIFGLKNIPVEL-HVLLNDDAETPTRMVGQKQVPILQKDDSRYM 59 Query: 84 YESAITCEYLDEAYPGKKLLPD-DPYEKACQKMILELFSKVPSLVGSFIRSQNKE----- 137 ES Y+D+ L P + + + +K+ L+ F +S E Sbjct: 60 PESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKL--LLPRFAKSAFDEFSTPA 117 Query: 138 ---------------------DYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYL 176 GL + + L++++ G +S D Sbjct: 118 ARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVKPNA--VNGE-LSEDDIQ 174 Query: 177 IWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTV 212 ++P L + ++ + M + + Sbjct: 175 LFPLLRNLTLVAGINWPS---RVADYRDNMAKQTQI 207 >3IR4-A nrPDB Length = 218 Score = 57.4 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 30/213 (14%), Positives = 70/213 (32%), Gaps = 30/213 (14%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLI 83 +++Y CPF + R++ K I E+ + ++ +VP+L+ + + Sbjct: 4 MKLYIYDHCPFCVKARMIFGLKNIPVELNVLQNDDEATPTRMIG-QKMVPILQKDDSRYL 62 Query: 84 YESAITCEYLDEAYPGKKLLPD-DPYEKACQKMILELFSKVPSLVGSFIRSQNKE-DYAG 141 ES Y+D L +P + + + +++ L+ F +S E Sbjct: 63 PESMDIVHYVDNLDGKPLLTGKRNPAIEEWLRKVNGYVNQL--LLPRFAKSAFDEFSTPA 120 Query: 142 LKEEFRKEFTK----LEEVLTNKKT--TFFGGN----------------SISMIDYLIWP 179 ++ F ++ + L + G + +S D ++P Sbjct: 121 ARQYFIRKKEASSGSFDNHLAHSAGLIKKIGDDLRLLDKLIVQPNAVNGELSEDDIHLFP 180 Query: 180 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTV 212 L + K+ + M + + Sbjct: 181 LLRNLTLVAGIHWPT---KVADYRDNMAKQTQI 210 >2YV7-A nrPDB Length = 260 Score = 56.3 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 34/194 (17%), Positives = 68/194 (35%), Gaps = 17/194 (8%) Query: 40 LVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPG 99 L+ + K I +V ++++ P F N P + G I E+ ++ + PG Sbjct: 52 LLAELKTISLKVTTVDMQKPPPDFRT-NFEATHPPILIDNGLAILENEKIERHIMKNIPG 110 Query: 100 K-KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLT 158 L D K +I L+ K+ + + E K+ + L+ Sbjct: 111 GYNLFVQD---KEVATLIENLYVKL-----KLMLVKKDE---AKNNALLSHLRKINDHLS 159 Query: 159 NKKTTFFGGNSISMIDYLIWPWFERLEA----MKLNECVDHTPKLKLWMAAMKEDPTVSA 214 + T F G+++ D + P + + E H L +M M + + Sbjct: 160 ARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQ 219 Query: 215 LLTSEKDWQGFLEL 228 +++D +L Sbjct: 220 SCPADQDIINHYKL 233 >2HNL-A nrPDB Length = 225 Score = 53.6 bits (127), Expect = 8e-08, Method: Composition-based stats. Identities = 37/184 (20%), Positives = 70/184 (38%), Gaps = 17/184 (9%) Query: 38 TRLVLKAKGIRHEVININLKNKPEW--FFKKNPFGLVPVLENSQGQLIYESAITCEYLDE 95 RL+ + +E N + EW + PFG VP+L G ++ ES Sbjct: 42 IRLLFALANVSYED---NRITRDEWKYLKPRTPFGHVPMLNV-SGNVLGESHAIEL---L 94 Query: 96 AYPGKKLLPDDPYEKACQKMIL----ELFSKVPSLVGSFIRSQNKEDYAGLKE-EFRKEF 150 LL + +E+A ++ ELF K+ ++ E + L E + Sbjct: 95 LGGRFGLLGTNDWEEAKIMAVVLNIDELFQKLIPWTHEKNTTKKAELFRNLSESDVMPFL 154 Query: 151 TKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDP 210 + E+ L T GN +S+ D ++ L+ ++ P+L ++ + + P Sbjct: 155 GRYEKFLKESTTGHIVGNKVSVADLTVFNMLMTLDD---EVKLEEYPQLASFVNKIGQMP 211 Query: 211 TVSA 214 + Sbjct: 212 GIKE 215 >1M0U-A nrPDB Length = 249 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 23/175 (13%), Positives = 58/175 (33%), Gaps = 17/175 (9%) Query: 48 RHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDP 107 +E + + P P G +PVLE G+ +++S +L + L P Sbjct: 74 EYEDVRVTRDEWPALKPTM-PMGQMPVLEV-DGKRVHQSISMARFLAKTV---GLCGATP 128 Query: 108 YEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRK--------EFTKLEEVLTN 159 +E ++++ + + + +++ KLE+ + + Sbjct: 129 WEDLQIDIVVDTIND---FRLKIAVVSYEPEDEIKEKKLVTLNAEVIPFYLEKLEQTVKD 185 Query: 160 KKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSA 214 ++ D + + M + ++ P L+ + A+ + A Sbjct: 186 NDG-HLALGKLTWADVYFAGITDYMNYMVKRDLLEPYPALRGVVDAVNALEPIKA 239 >5LKB-A nrPDB Length = 378 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 43/310 (13%), Positives = 84/310 (27%), Gaps = 108/310 (34%) Query: 4 ESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLV------------------LKAK 45 S R P +G +Y CP+A RT + L K Sbjct: 18 SSFRETISKQHPIYKPAKGRYWLYVSLACPWAHRTLITRALKGLTSVIGCSVVHWHLDEK 77 Query: 46 G---IRHEVININ----------------------------------------------- 55 G + E + Sbjct: 78 GWRFLDMEKQLEDSEDFLEHWHDVAGGIRTAKEDSSKSFAEIKNDSQRFMVDATNEPHYG 137 Query: 56 LKNKPEWFFKKNPFG----LVPVLENSQGQLIY--ESAITC---------EYLDEAYPGK 100 K + ++K +P VPVL + + Q I ES+ E++D+ + Sbjct: 138 YKRISDLYYKSDPQYSARFTVPVLWDLETQTIVNNESSEIIRILNSSAFDEFVDDDHKKT 197 Query: 101 KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNK 160 L+P + ++ + + V ++ E Y + K+E++L++K Sbjct: 198 DLVPAQLKTQIDDFNSW-VYDSINNGVYKTGFAEKAEVYESEVNNVFEHLDKVEKILSDK 256 Query: 161 KTT-----------------FFGGNSISMIDYLIWPWFERLE-------AMKLNECVDHT 196 + F G+ ++ D ++ R + Sbjct: 257 YSKLKAKYGEEDRQKILGEFFTVGDQLTEADIRLYTTVIRFDPVYVQHFKCNFTSIRAGY 316 Query: 197 PKLKLWMAAM 206 P + LW+ + Sbjct: 317 PFIHLWVRNL 326 >4LMV-A nrPDB Length = 252 Score = 48.6 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 44/110 (40%), Gaps = 15/110 (13%) Query: 30 RFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKK--NPFGL---------VPVLENS 78 + P + R L KGI+++ + + + K P G VPV+ + Sbjct: 19 PWSPNTWKIRYALNIKGIKYKTEWVEYPDIEDVVKKLGGKPTGKKPDGRDHYTVPVIYDP 78 Query: 79 QGQLIYESAI-TCEYLDEAYPG-KKLLPD--DPYEKACQKMILELFSKVP 124 + + E I +YLD+AYP +L P D ++ A + + P Sbjct: 79 NTKTVVEDGIKIAKYLDDAYPDTPRLFPAGTDAFQAAFDDFVWSVTLAFP 128 >2PBJ-A nrPDB Length = 290 Score = 48.2 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 27/136 (19%), Positives = 55/136 (40%), Gaps = 12/136 (8%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL- 82 + +Y + CPF + R L + ++V+ +N + E K + + VP+L +G+ Sbjct: 15 LTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVLRAE--IKFSSYRKVPILVAQEGESS 72 Query: 83 --IYESAITCE----YLDEAYPGKKLLPDDPYEKACQ---KMILELFSKVPSLVGSFIRS 133 + +S++ YL P ++++ P KA K + E +K ++ Sbjct: 73 QQLNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNDQGKEVTEFGNKYWLMLNEKEAQ 132 Query: 134 QNKEDYAGLKEEFRKE 149 Q EE + Sbjct: 133 QVYSGKEARTEEMKWR 148 Score = 35.5 bits (80), Expect = 0.020, Method: Composition-based stats. Identities = 11/97 (11%), Positives = 35/97 (36%), Gaps = 3/97 (3%) Query: 115 MILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLT---NKKTTFFGGNSIS 171 + +K ++ S+ + L++ R++ + + K F GG + Sbjct: 185 AVEGAVAKYMGAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPN 244 Query: 172 MIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 + D ++ +E + + + ++ W ++ Sbjct: 245 LADLAVYGVLRVMEGLDAFDDLMQHTHIQPWYLRVER 281 >5CAX-A nrPDB Length = 101 Score = 43.6 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 30/72 (41%), Gaps = 6/72 (8%) Query: 18 PVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPE------WFFKKNPFGL 71 + G I +Y + C + ++T+ +L G+ E + ++L + E + NP Sbjct: 16 GIDRGKIVMYGLSTCVWCKKTKKLLTDLGVDFEYVFVDLLEEEEKSNAIKQVSRFNPSVS 75 Query: 72 VPVLENSQGQLI 83 P + + I Sbjct: 76 FPTTILNDEKAI 87 >3GRX-A nrPDB Length = 82 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININL-KNKPEWFFKKNPFGLVPVLENS 78 ++ IY+ CP++ R + +L +KG+ + + I+ K E K++ VP + Sbjct: 1 ANVEIYTKETCPYSHRAKALLSSKGVSFQELPIDGNAAKREEMIKRSGRTTVPQIFID 58 >3QMX-A nrPDB Length = 99 Score = 38.2 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 19/42 (45%) Query: 17 GPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKN 58 G I IY+ CPF R +LK KG+ + I+ N Sbjct: 11 GSAVSAKIEIYTWSTCPFCMRALALLKRKGVEFQEYCIDGDN 52 >4LA1-A nrPDB Length = 602 Score = 37.8 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 34/78 (43%), Gaps = 5/78 (6%) Query: 19 VPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININ-LKNKP---EWFFKKNPFGLVPV 74 + ++ ++S CPF ++ + VL I+H I ++ L N + + VP Sbjct: 21 IESAAVIVFSKTTCPFCKKLKDVLAEAKIKHATIELDQLSNGSVIQKALSNFSKIETVPQ 80 Query: 75 LENSQGQLIYESAITCEY 92 + +G+ I +S Y Sbjct: 81 MFV-RGKFIGDSKAVLNY 97 >2X8H-A nrPDB Length = 598 Score = 37.4 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 34/78 (43%), Gaps = 5/78 (6%) Query: 19 VPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININ-LKNKPEW---FFKKNPFGLVPV 74 V ++ ++S CP+ ++ + VL I+H I ++ L N + VP Sbjct: 15 VDSAAVILFSKTTCPYCKKVKDVLAEAKIKHATIELDQLSNGSAIQKCLASFSKIETVPQ 74 Query: 75 LENSQGQLIYESAITCEY 92 + +G+ I +S +Y Sbjct: 75 MFV-RGKFIGDSQTVLKY 91 >2KLX-A nrPDB Length = 89 Score = 36.6 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Query: 21 EGSIR---IYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLEN 77 GS++ +Y+ CP+ +R R +L KG+++ I+ + + E + N P + Sbjct: 2 PGSMKEIILYTRPNCPYCKRARDLLDKKGVKYTDIDASTSLRQEMVQRANGRNTFPQIFI 61 Query: 78 SQGQL 82 + Sbjct: 62 GDYHV 66 >3NZN-A nrPDB Length = 103 Score = 34.7 bits (78), Expect = 0.038, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 29/72 (40%), Gaps = 6/72 (8%) Query: 18 PVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININL------KNKPEWFFKKNPFGL 71 V G + +Y + C + ++T+ +L G+ + + ++ + E + NP Sbjct: 18 GVDRGKVIMYGLSTCVWCKKTKKLLTDLGVDFDYVYVDRLEGKEEEEAVEEVRRFNPSVS 77 Query: 72 VPVLENSQGQLI 83 P + + I Sbjct: 78 FPTTIINDEKAI 89 >4TR1-A nrPDB Length = 92 Score = 34.7 bits (78), Expect = 0.040, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 32/59 (54%), Gaps = 2/59 (3%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP-EWFFKKNPFGLVP-VLENSQ 79 +I IY+ +CP++++ +L +KG+ + +++ +K E K + VP V + + Sbjct: 3 NITIYTKNYCPYSKKAVSLLSSKGVDFKEVDVTHDSKAFEDVMAKTGWDTVPQVFVDEE 61 >3IC4-A nrPDB Length = 92 Score = 34.3 bits (77), Expect = 0.047, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 26/64 (40%), Gaps = 6/64 (9%) Query: 26 IYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP------EWFFKKNPFGLVPVLENSQ 79 +Y + CP +RT LK +G+ EVI I+ E + VPV+ Sbjct: 16 MYGLSTCPHCKRTLEFLKREGVDFEVIWIDKLEGEERKKVIEKVHSISGSYSVPVVVKGD 75 Query: 80 GQLI 83 ++ Sbjct: 76 KHVL 79 >1Z7R-A nrPDB Length = 117 Score = 32.0 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 34/85 (40%), Gaps = 9/85 (10%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININ-LKNKPEWFFKKNP---FGLVPVLENSQ 79 + ++S +C + R + +L G ++V+ ++ L + + G VP + Sbjct: 23 VVVFSKTYCGYCNRVKQLLTQVGASYKVVELDELSDGSQLQSALAHWTGRGTVPNVFIG- 81 Query: 80 GQLIYESAITCEYLDEAYPGKKLLP 104 G+ I E + +LLP Sbjct: 82 GKQIGGCDTVV----EKHQRNELLP 102 >1NM3-A nrPDB Length = 241 Score = 32.0 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 2/89 (2%) Query: 4 ESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWF 63 A ++ K AP V E SI I++ CPF + + +L KG+ E I + Sbjct: 153 SDADTMLKYLAPQHQVQE-SISIFTKPGCPFCAKAKQLLHDKGLSFEEIILGHDATIVSV 211 Query: 64 FKKNPFGLVPVLENSQGQLIYESAITCEY 92 + VP + G+ I S +Y Sbjct: 212 RAVSGRTTVPQVFIG-GKHIGGSDDLEKY 239 >5W1J-A nrPDB Length = 584 Score = 31.2 bits (69), Expect = 0.37, Method: Composition-based stats. Identities = 7/48 (14%), Positives = 21/48 (43%) Query: 19 VPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKK 66 + ++ +++ FCP+ ++ I ++++LK + K Sbjct: 12 INNAAVLVFAKSFCPYCKKVMERFNNLKIPFGYLDLDLKKNGSDYQKM 59 >4XRU-B nrPDB Length = 394 Score = 30.8 bits (68), Expect = 0.51, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 42/104 (40%), Gaps = 11/104 (10%) Query: 110 KACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE-FRKEFTKLEEVLTNKKTTFFGGN 168 + Q + F +P + + + D G + F K F L+EV T+ + F N Sbjct: 193 RQYQSIRDFKFLDLPHYQQNIQLFKRQLDIFGKEAAPFFKPFNILKEVYTDGREHFVNDN 252 Query: 169 ----SISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 208 I+ D+L + + +R + P+++ W+ + + Sbjct: 253 LSFQQINDDDFLHYQFTDR------EDFEAKYPQIRAWVDQVNQ 290 >1H75-A nrPDB Length = 81 Score = 30.8 bits (68), Expect = 0.51, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 24/60 (40%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL 82 I IY+ C T+ ++ +G E+IN++ + + F +PV+ Sbjct: 2 RITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAAEALRAQGFRQLPVVIAGDLSW 61 >2LQQ-A nrPDB Length = 92 Score = 30.8 bits (68), Expect = 0.57, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 27/66 (40%), Gaps = 2/66 (3%) Query: 21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG--LVPVLENS 78 ++ IY+ +C + R + L A I ++ ++I F G VP ++ + Sbjct: 3 TAALTIYTTSWCGYCLRLKTALTANRIAYDEVDIEHNRAAAEFVGSVNGGNRTVPTVKFA 62 Query: 79 QGQLIY 84 G + Sbjct: 63 DGSTLT 68 >1HX8-A nrPDB Length = 299 Score = 30.5 bits (67), Expect = 0.77, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 22/68 (32%), Gaps = 11/68 (16%) Query: 17 GPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININ---LKNKPEW--FFKKNP--- 68 VP G + PF R L K + + + + +K E N Sbjct: 122 MGVPGGRM---GYDMSPFIRRYAKYLNEKSLSYRAMAFDFCKVKRGKEEGSLRSMNAEKL 178 Query: 69 FGLVPVLE 76 +PVL+ Sbjct: 179 LKTLPVLQ 186 >2MZC-A nrPDB Length = 92 Score = 30.1 bits (66), Expect = 0.91, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 19/45 (42%), Gaps = 5/45 (11%) Query: 21 EGSIR---IYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEW 62 GS+ IY+ CP+ R + +L KG I+ PE Sbjct: 2 PGSMVDVIIYTRPGCPYCARAKALLARKGAEFN--EIDASATPEL 44 >4RK9-A nrPDB Length = 401 Score = 30.1 bits (66), Expect = 0.92, Method: Composition-based stats. Identities = 25/140 (17%), Positives = 47/140 (33%), Gaps = 8/140 (5%) Query: 93 LDEAYPG---KKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKE 149 L E + K+L+ D A ++EL ++ + + + D + + + Sbjct: 214 LAETFKEMQEKQLINKDIL-TAKPSQLVELMAQE-KIGFTLSVTSIGPDTREVNPDIQLG 271 Query: 150 FTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKED 209 V K ++ GG ++ +W E LE K PK +A Sbjct: 272 VMPTPAVYEGDKPSWIGGERHTVA---VWKDSEHLEEAKRFIEFAAQPKYVKKIAEATSF 328 Query: 210 PTVSALLTSEKDWQGFLELY 229 P +E + F + Y Sbjct: 329 PQALTNTEAENYYSKFYDQY 348 >3LGC-A nrPDB Length = 89 Score = 29.7 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 10/68 (14%), Positives = 25/68 (36%), Gaps = 8/68 (11%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVINI-NLKNKPEWFFKKN-------PFGLVPV 74 ++IY+ CP+ + + I + I + + +++ + N P VP Sbjct: 5 KVKIYTRNGCPYCVWAKQWFEENNIAFDETIIDDYAQRSKFYDEMNQSGKVIFPISTVPQ 64 Query: 75 LENSQGQL 82 + + Sbjct: 65 IFIDDEHI 72 >3PFO-A nrPDB Length = 433 Score = 29.3 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 30/85 (35%), Gaps = 2/85 (2%) Query: 48 RHEVININLKNKPEWFF--KKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPD 105 + ++++ + P+ +P G + V+ + S I ++D G L Sbjct: 65 TFSLADVDIASHPKAAPMDTIDPAGSMQVVATADSDGKGRSLILQGHIDVVPEGPVDLWS 124 Query: 106 DPYEKACQKMILELFSKVPSLVGSF 130 DP +A + + + G Sbjct: 125 DPPYEAKVRDGWMIGRGAQDMKGGV 149 >3GNJ-A nrPDB Length = 111 Score = 28.9 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 9/63 (14%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHE----VININLKNKPEWFFKKNPFGLVPVLENSQ 79 + ++S + C ++ VL+ + +E ++++ + F + + G+ +L Sbjct: 26 LVMFSRKNCHVCQKVTPVLEELRLNYEESFGFYYVDVEEEKTLFQRFSLKGVPQILYFKD 85 Query: 80 GQL 82 G+ Sbjct: 86 GEY 88 >4FIW-A nrPDB Length = 77 Score = 28.9 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 24/59 (40%) Query: 24 IRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQL 82 I +Y+ C T+ L G+ +++++I+L + + + PV+ Sbjct: 3 ITVYTKPACVQCNATKKALDRAGLEYDLVDISLDEEAREYVLALGYLQAPVVVADGSHW 61 >2DYB-A nrPDB Length = 341 Score = 28.5 bits (62), Expect = 2.4, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 41/128 (32%), Gaps = 11/128 (8%) Query: 103 LPDDPYEKACQKMILELFSKVPSLVGSF-IRSQNKEDYAGLKEEFRKEFTKLEEVLTNKK 161 LPDD A I E V ++++ Y + ++F L+ L + Sbjct: 18 LPDDVAISANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRY--RQFHALQSKLEERF 75 Query: 162 TTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHT--PKLKLWMAAMKEDPTVSALLTSE 219 +S S P + + + + P L +M ++ P +L E Sbjct: 76 GP----DSKSSALACTLPTLPAKVYVGVKQEIAEMRIPALNAYMKSLLSLPVW--VLMDE 129 Query: 220 KDWQGFLE 227 F + Sbjct: 130 DVRIFFYQ 137 >1R7H-A nrPDB Length = 75 Score = 28.1 bits (61), Expect = 3.0, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 26/62 (41%), Gaps = 4/62 (6%) Query: 23 SIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLV--PVLENSQG 80 SI +Y+ C T+ L G+ + ++I+L ++ + G V PV+E Sbjct: 2 SITLYTKPACVQCTATKKALDRAGLAYNTVDISLDDEARDYVM--ALGYVQAPVVEVDGE 59 Query: 81 QL 82 Sbjct: 60 HW 61 >1H6H-A nrPDB Length = 143 Score = 28.1 bits (61), Expect = 3.4, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 41/128 (32%), Gaps = 11/128 (8%) Query: 103 LPDDPYEKACQKMILELFSKVPSLVGSF-IRSQNKEDYAGLKEEFRKEFTKLEEVLTNKK 161 LPDD A I E V ++++ Y + ++F L+ L + Sbjct: 15 LPDDVAISANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRY--RQFHALQSKLEERF 72 Query: 162 TTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHT--PKLKLWMAAMKEDPTVSALLTSE 219 +S S P + + + + P L +M ++ P +L E Sbjct: 73 GP----DSKSSALACTLPTLPAKVYVGVKQEIAEMRIPALNAYMKSLLSLPVW--VLMDE 126 Query: 220 KDWQGFLE 227 F + Sbjct: 127 DVRIFFYQ 134 >2LV3-A nrPDB Length = 118 Score = 28.1 bits (61), Expect = 3.7, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 26/59 (44%), Gaps = 4/59 (6%) Query: 19 VPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK----PEWFFKKNPFGLVP 73 + + I+S +CP + R + + + G+ + ++ ++ + E + + VP Sbjct: 29 IEGNRVMIFSKSYCPHSTRVKELFSSLGVVYNILELDQVDDGASVQEVLTEISNQKTVP 87 >3UG7-A nrPDB Length = 349 Score = 27.8 bits (60), Expect = 4.5, Method: Composition-based stats. Identities = 26/174 (14%), Positives = 51/174 (29%), Gaps = 40/174 (22%) Query: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE 145 SA T YL E ++ DP E + + G + D EE Sbjct: 43 SAATGVYLAEKGLKVVIVSTDPAHSLRDIFEQEFGHEPTKVKGYDNLYVVEIDPQKAMEE 102 Query: 146 FRKEFTK-----------LEEVLT--------------NKKTTFFGGNSISMIDYLIWPW 180 ++++ LE+ L + + N ++ + P Sbjct: 103 YKEKLKAQIEENPFLGEMLEDQLEMAALSPGTDESAAFDVFLKYMDSNEFDVVIFDTAPT 162 Query: 181 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSP 234 L + + E +D ++ L+ K GF+++ + P Sbjct: 163 GHTLRFLGMPEVMDKY---------------MTKLIKLRKQMSGFMKMMKKLLP 201 >3MZS-A nrPDB Length = 486 Score = 27.8 bits (60), Expect = 4.7, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 13/36 (36%) Query: 4 ESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTR 39 S ++ S P P G + +Y ++R Sbjct: 2 ASTKTPRPYSEIPSPGDNGWLNLYHFWREKGSQRIH 37 >3N9Z-A nrPDB Length = 487 Score = 27.8 bits (60), Expect = 4.8, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 12/36 (33%) Query: 5 SARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRL 40 S RS + P P G + +Y + L Sbjct: 1 STRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHL 36 >4PFT-A nrPDB Length = 544 Score = 27.4 bits (59), Expect = 5.7, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 24/58 (41%), Gaps = 2/58 (3%) Query: 177 IWPWFERLEAM--KLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQN 232 +W W R+E + + + V P+ + W + P V + K + L+ +N Sbjct: 107 VWNWLGRIERVDERTLKFVFSDPRYQEWKQMLINTPIVPKHIWENKTEEEVLQAANEN 164 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.130 0.344 Lambda K H 0.267 0.0402 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,043,929 Number of Sequences: 36641 Number of extensions: 342460 Number of successful extensions: 1582 Number of sequences better than 10.0: 173 Number of HSP's better than 10.0 without gapping: 201 Number of HSP's successfully gapped in prelim test: 67 Number of HSP's that attempted gapping in prelim test: 1062 Number of HSP's gapped (non-prelim): 282 length of query: 241 length of database: 10,336,785 effective HSP length: 94 effective length of query: 147 effective length of database: 6,892,531 effective search space: 1013202057 effective search space used: 1013202057 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 57 (26.6 bits)