BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P77774 (392 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3P1L-A nrPDB 752 0.0 4PK1-A nrPDB 751 0.0 4HDJ-A nrPDB 182 2e-46 4IMM-A nrPDB 135 2e-32 1FLG-A nrPDB 47 2e-05 1YIQ-A nrPDB 39 0.004 1KB0-A nrPDB 37 0.011 1KV9-A nrPDB 37 0.013 2AD6-A nrPDB 35 0.041 5WLC-LV nrPDB 35 0.051 1H4I-A nrPDB 33 0.21 6FKW-A nrPDB 33 0.27 4TQO-B nrPDB 32 0.39 5YZG-W nrPDB 31 1.0 6QDV-o nrPDB 31 1.2 3N2Z-B nrPDB 29 2.7 3KLB-A nrPDB 29 3.4 6DAM-A nrPDB 29 3.5 1PQU-A nrPDB 28 5.6 5XM3-A nrPDB 28 8.6 >3P1L-A nrPDB Length = 393 Score = 752 bits (1941), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/375 (99%), Positives = 373/375 (99%) Query: 18 SGCSLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADR 77 S SLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADR Sbjct: 19 SHMSLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADR 78 Query: 78 AGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTS 137 AGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTS Sbjct: 79 AGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTS 138 Query: 138 DGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGE 197 DGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGE Sbjct: 139 DGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGE 198 Query: 198 SAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGV 257 SAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGV Sbjct: 199 SAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGV 258 Query: 258 VFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLW 317 VFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLW Sbjct: 259 VFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLW 318 Query: 318 TQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGK 377 TQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGK Sbjct: 319 TQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGK 378 Query: 378 LLIQAKDGTVYSITR 392 LLIQAKDGTVYSITR Sbjct: 379 LLIQAKDGTVYSITR 393 >4PK1-A nrPDB Length = 645 Score = 751 bits (1940), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/373 (99%), Positives = 372/373 (99%) Query: 20 CSLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAG 79 SLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAG Sbjct: 273 ASLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAG 332 Query: 80 LVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDG 139 LVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDG Sbjct: 333 LVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDG 392 Query: 140 TVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESA 199 TVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESA Sbjct: 393 TVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESA 452 Query: 200 PTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVF 259 PTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVF Sbjct: 453 PTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVF 512 Query: 260 ALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQ 319 ALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQ Sbjct: 513 ALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQ 572 Query: 320 SDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLL 379 SDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLL Sbjct: 573 SDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLL 632 Query: 380 IQAKDGTVYSITR 392 IQAKDGTVYSITR Sbjct: 633 IQAKDGTVYSITR 645 >4HDJ-A nrPDB Length = 367 Score = 182 bits (463), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 109/357 (30%), Positives = 179/357 (50%), Gaps = 10/357 (2%) Query: 35 LPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWS 94 L + + + WS SVG G G+ Y+ L PA+ + +YAA G V A+ + G +W Sbjct: 17 LTDFKEEVVLSKQWSRSVGDGQGDLYNLLEPAVDGSTIYAASAEGRVMAIQRETGDVLWK 76 Query: 95 VSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSR 154 L L T+ G V AL+ + G W +V E LS Sbjct: 77 KDLERPVSGGVGVGYGLVLVGTLRG----------DVIALDEATGKKKWTKRVNSEVLSA 126 Query: 155 PVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVGGDNG 214 P + +V++ T + +L L+ A G +W +P L+LRG AP A A+ G +G Sbjct: 127 PATNGDVVVVQTQDDKLIGLDAASGDQRWIYESTVPVLTLRGTGAPLIAGNMALAGLASG 186 Query: 215 RVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRS 274 +V AV +++G IW+QR++ G +E+DR+ D+D ++ ++ ++Y G ALD+ S Sbjct: 187 KVVAVDVQRGLPIWEQRVAIPQGRSELDRVVDIDGGLLLSGDTLYVVSYQGRAAALDVNS 246 Query: 275 GQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYN 334 G+++W+RE S IY+ + V L G +LW L R L++P +++ Sbjct: 247 GRLLWQREASSYVGVAEGFGNIYVSQASGSVEGLDSRGASSLWNNDALARRQLSAPAVFS 306 Query: 335 GNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSIT 391 N+VVGD EGY+H ++ DGRFV +++VDS G + P+ + + G + + T Sbjct: 307 SNVVVGDLEGYVHLLSQVDGRFVGRERVDSDGVRVRPLVVGSWMYVFGNGGKLVAYT 363 >4IMM-A nrPDB Length = 399 Score = 135 bits (341), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 93/324 (28%), Positives = 160/324 (49%), Gaps = 19/324 (5%) Query: 67 LADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTV--SGGHVYI 124 LAD ++ AA R+G+V + E W +++GGV + G I Sbjct: 80 LADGMI-AASRSGIVSGY------------MGESIAWQYNAEDVITGGVGIDDQGSVAVI 126 Query: 125 GSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWT 184 G+ ++ AL+ G W ++A +L+ ++S V++ T++G + L+ GA W Sbjct: 127 GTRSGKLIALDARTGAARWVVELASSSLAPALISGDKVIVITNSGTIFGLDINSGATVWQ 186 Query: 185 VNLDMPSLSLRGESAPTTAFGAAV-VGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDR 243 +P+ S+RG + P V +GG +GR+ A+ G +W +R+ A GS EID+ Sbjct: 187 YATQVPNTSVRGMAKPLALDARTVLIGGADGRIHALDTMTGAPVWTRRVGLAMGSGEIDQ 246 Query: 244 LSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQND 303 L D+D TP VV+ ++A +Y+G L D+ +G+ M+ EL S + + + Sbjct: 247 LRDIDGTPTVVDHYLYAASYSGQLAGFDMTTGRTMFVSELSSTKKLTTLADAVIGSSTDG 306 Query: 304 RVMALTIDGGVTLWTQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVD 363 V+A G LW DL +R LT+PV + VGD++G +H +N G+ ++ + + Sbjct: 307 DVVAFNRMTGEKLWENHDLKYRGLTNPVTIGTYIAVGDADGVVHILN-HQGQIIS--RAN 363 Query: 364 SSGFQTEPVAADGKLLIQAKDGTV 387 + G T + +L Q+ DG V Sbjct: 364 TKGALTNLTVINNRLYAQSADGVV 387 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 67/287 (23%), Positives = 123/287 (42%), Gaps = 71/287 (24%) Query: 77 RAGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNT 136 R+G + AL+A G W V LA S PAL +SG V + + ++ L+ Sbjct: 129 RSGKLIALDARTGAARWVVELASS----SLAPAL------ISGDKVIVITNSGTIFGLDI 178 Query: 137 SDGTVAWQ-------TKVAGEALSRPVVSDG-LVLIHTSNGQLQALNEADGAVKWT--VN 186 + G WQ T V G +++P+ D VLI ++G++ AL+ GA WT V Sbjct: 179 NSGATVWQYATQVPNTSVRG--MAKPLALDARTVLIGGADGRIHALDTMTGAPVWTRRVG 236 Query: 187 LDMPSLS---LRG-ESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEID 242 L M S LR + PT +G+++ M G+ ++ +S+ + + ++ Sbjct: 237 LAMGSGEIDQLRDIDGTPTVVDHYLYAASYSGQLAGFDMTTGRTMF---VSELSSTKKLT 293 Query: 243 RLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWK------RELG---SVNDFIVDG 293 L+D V + +G++ A + +G+ +W+ R L ++ +I G Sbjct: 294 TLADA----------VIGSSTDGDVVAFNRMTGEKLWENHDLKYRGLTNPVTIGTYIAVG 343 Query: 294 NR---IYLVDQ--------------------NDRVMALTIDGGVTLW 317 + +++++ N+R+ A + DG VT+W Sbjct: 344 DADGVVHILNHQGQIISRANTKGALTNLTVINNRLYAQSADGVVTVW 390 >1FLG-A nrPDB Length = 582 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 18/153 (11%) Query: 31 KMSPLPTV--ENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADD 88 + SPL V +N F T AWS S G + ++D V+Y + AL+A Sbjct: 29 RWSPLKQVNADNVFKLTPAWSYSFGDEKQRGQES-QAIVSDGVIYVTASYSRLFALDAKT 87 Query: 89 GKEIWSVSLAEKDGWFSKEPA--LLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTK 146 GK +W+ + D P +++ G + G V+ G+ A V ALN + G V W+ K Sbjct: 88 GKRLWTYNHRLPD---DIRPCCDVVNRGAAIYGDKVFFGTLDASVVALNKNTGKVVWKKK 144 Query: 147 VAGEAL------SRPVVSDG----LVLIHTSNG 169 A + +V DG ++LIH S+G Sbjct: 145 FADHGAGYTMTGAPTIVKDGKTGKVLLIHGSSG 177 Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust. Identities = 18/84 (21%), Positives = 37/84 (44%), Gaps = 11/84 (13%) Query: 252 VVVNGVVFALAYNGNLTALDLRSGQIMWKRELGSVNDF-----------IVDGNRIYLVD 300 +V +GV++ A L ALD ++G+ +W +D + G++++ Sbjct: 65 IVSDGVIYVTASYSRLFALDAKTGKRLWTYNHRLPDDIRPCCDVVNRGAAIYGDKVFFGT 124 Query: 301 QNDRVMALTIDGGVTLWTQSDLLH 324 + V+AL + G +W + H Sbjct: 125 LDASVVALNKNTGKVVWKKKFADH 148 Score = 27.7 bits (60), Expect = 9.0, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 16/30 (53%) Query: 66 ALADNVVYAADRAGLVKALNADDGKEIWSV 95 A A N+V+ G KA +A GKE+W Sbjct: 494 ATAGNLVFTGTGDGYFKAFDAKSGKELWKF 523 >1YIQ-A nrPDB Length = 689 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 24/142 (16%) Query: 238 STEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWK--------RELGSVNDF 289 S ++D V+ TP+VV+GV++ + ALD R G+++WK R + D Sbjct: 53 SYKLDLDRGVEATPIVVDGVMYTTGPFSVVYALDARDGRLIWKYDPQSDRHRAGEACCDA 112 Query: 290 IVDG-----NRIYLVDQNDRVMALTIDGGVTLW---TQSDLL--HRLLTSPVLYNGNLVV 339 + G ++Y+ + R+ A+ G W T++D + + +P + NG +V+ Sbjct: 113 VNRGVAVWKGKVYVGVLDGRLEAIDAKTGQRAWSVDTRADHKRSYTITGAPRVVNGKVVI 172 Query: 340 GDS------EGYLHWINVEDGR 355 G+ GY+ + E G+ Sbjct: 173 GNGGAEFGVRGYVTAYDAETGK 194 Score = 36.6 bits (83), Expect = 0.019, Method: Compositional matrix adjust. Identities = 48/165 (29%), Positives = 67/165 (40%), Gaps = 22/165 (13%) Query: 65 PALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDGWFSKEPAL--LSGGVTVSGGHV 122 P + D V+Y +V AL+A DG+ IW + D + E ++ GV V G V Sbjct: 66 PIVVDGVMYTTGPFSVVYALDARDGRLIWKYD-PQSDRHRAGEACCDAVNRGVAVWKGKV 124 Query: 123 YIGSEKAQVYALNTSDGTVAWQT------KVAGEALSRPVVSDGLVLIHTS------NGQ 170 Y+G ++ A++ G AW K + P V +G V+I G Sbjct: 125 YVGVLDGRLEAIDAKTGQRAWSVDTRADHKRSYTITGAPRVVNGKVVIGNGGAEFGVRGY 184 Query: 171 LQALNEADGAVKW---TVNLDMPSLSLRG---ESAPTTAFGAAVV 209 + A + G W TV D P L G E A T FG A V Sbjct: 185 VTAYDAETGKEAWRFYTVPGD-PKLPPEGKGMEIAAKTWFGDAYV 228 >1KB0-A nrPDB Length = 677 Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust. Identities = 30/141 (21%), Positives = 62/141 (43%), Gaps = 24/141 (17%) Query: 238 STEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRE--------LGSVNDF 289 S ++ V+ TPVVV+G+++ A + A+D R+G +W + D Sbjct: 60 SYNLESTRGVEATPVVVDGIMYVSASWSVVHAIDTRTGNRIWTYDPQIDRSTGFKGCCDV 119 Query: 290 IVDG-----NRIYLVDQNDRVMALTIDGGVTLWTQSDLLHR-----LLTSPVLYNGNLVV 339 + G ++Y+ + R++AL G +W Q+ + + +P ++ G +++ Sbjct: 120 VNRGVALWKGKVYVGAWDGRLIALDAATGKEVWHQNTFEGQKGSLTITGAPRVFKGKVII 179 Query: 340 GDS------EGYLHWINVEDG 354 G+ GY+ + E G Sbjct: 180 GNGGAEYGVRGYITAYDAETG 200 Score = 35.8 bits (81), Expect = 0.031, Method: Compositional matrix adjust. Identities = 38/160 (23%), Positives = 63/160 (39%), Gaps = 9/160 (5%) Query: 130 QVYALNTSDGTVAWQTKVAGE--ALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNL 187 Q+ A N D +AW + + PVV DG++ + S + A++ G WT + Sbjct: 46 QINAANVKDLGLAWSYNLESTRGVEATPVVVDGIMYVSASWSVVHAIDTRTGNRIWTYDP 105 Query: 188 DMP-SLSLRG-----ESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQA-TGSTE 240 + S +G G VG +GR+ A+ G+ +W Q + GS Sbjct: 106 QIDRSTGFKGCCDVVNRGVALWKGKVYVGAWDGRLIALDAATGKEVWHQNTFEGQKGSLT 165 Query: 241 IDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWK 280 I V V++ G +TA D +G+ W+ Sbjct: 166 ITGAPRVFKGKVIIGNGGAEYGVRGYITAYDAETGERKWR 205 Score = 35.0 bits (79), Expect = 0.060, Method: Compositional matrix adjust. Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 13/132 (9%) Query: 65 PALADNVVYAADRAGLVKALNADDGKEIWSVSLA-EKDGWFSKEPALLSGGVTVSGGHVY 123 P + D ++Y + +V A++ G IW+ ++ F +++ GV + G VY Sbjct: 73 PVVVDGIMYVSASWSVVHAIDTRTGNRIWTYDPQIDRSTGFKGCCDVVNRGVALWKGKVY 132 Query: 124 IGSEKAQVYALNTSDGTVAW-QTKVAGEALS-----RPVVSDGLVLI------HTSNGQL 171 +G+ ++ AL+ + G W Q G+ S P V G V+I + G + Sbjct: 133 VGAWDGRLIALDAATGKEVWHQNTFEGQKGSLTITGAPRVFKGKVIIGNGGAEYGVRGYI 192 Query: 172 QALNEADGAVKW 183 A + G KW Sbjct: 193 TAYDAETGERKW 204 >1KV9-A nrPDB Length = 668 Score = 37.0 bits (84), Expect = 0.013, Method: Compositional matrix adjust. Identities = 28/132 (21%), Positives = 55/132 (41%), Gaps = 6/132 (4%) Query: 155 PVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAV------ 208 P+ DG++ S ++ A++ A G W + ++ + R G A+ Sbjct: 62 PLFHDGVIYTSMSWSRVIAVDAASGKELWRYDPEVAKVKARTSCCDAVNRGVALWGDKVY 121 Query: 209 VGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLT 268 VG +GR+ A+ + G+ IW Q+ + I V V++ G ++ Sbjct: 122 VGTLDGRLIALDAKTGKAIWSQQTTDPAKPYSITGAPRVVKGKVIIGNGGAEYGVRGFVS 181 Query: 269 ALDLRSGQIMWK 280 A D +G++ W+ Sbjct: 182 AYDADTGKLAWR 193 Score = 34.7 bits (78), Expect = 0.066, Method: Compositional matrix adjust. Identities = 23/119 (19%), Positives = 57/119 (47%), Gaps = 17/119 (14%) Query: 240 EIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRE------------LGSVN 287 ++D ++ TP+ +GV++ + A+D SG+ +W+ + +VN Sbjct: 51 DLDNTRGLEATPLFHDGVIYTSMSWSRVIAVDAASGKELWRYDPEVAKVKARTSCCDAVN 110 Query: 288 DFI-VDGNRIYLVDQNDRVMALTIDGGVTLWTQSDL----LHRLLTSPVLYNGNLVVGD 341 + + G+++Y+ + R++AL G +W+Q + + +P + G +++G+ Sbjct: 111 RGVALWGDKVYVGTLDGRLIALDAKTGKAIWSQQTTDPAKPYSITGAPRVVKGKVIIGN 169 Score = 32.0 bits (71), Expect = 0.53, Method: Compositional matrix adjust. Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 16/111 (14%) Query: 65 PALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSG------GVTVS 118 P D V+Y + V A++A GKE+W D +K A S GV + Sbjct: 62 PLFHDGVIYTSMSWSRVIAVDAASGKELWRY-----DPEVAKVKARTSCCDAVNRGVALW 116 Query: 119 GGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEA-----LSRPVVSDGLVLI 164 G VY+G+ ++ AL+ G W + A P V G V+I Sbjct: 117 GDKVYVGTLDGRLIALDAKTGKAIWSQQTTDPAKPYSITGAPRVVKGKVII 167 Score = 28.1 bits (61), Expect = 6.5, Method: Compositional matrix adjust. Identities = 27/114 (23%), Positives = 46/114 (40%), Gaps = 5/114 (4%) Query: 170 QLQALNEADGAVKWTVNLDMPSLSLRG-ESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIW 228 Q+ A N + W ++LD + RG E+ P G RV AV G+ +W Sbjct: 35 QIDASNVRSLGLAWYMDLD----NTRGLEATPLFHDGVIYTSMSWSRVIAVDAASGKELW 90 Query: 229 QQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRE 282 + A V+ + V+ +G L ALD ++G+ +W ++ Sbjct: 91 RYDPEVAKVKARTSCCDAVNRGVALWGDKVYVGTLDGRLIALDAKTGKAIWSQQ 144 >2AD6-A nrPDB Length = 571 Score = 35.4 bits (80), Expect = 0.041, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 32/64 (50%) Query: 220 LMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMW 279 L + G+++WQ + Q + + VD G + NG+L ALD ++G+I W Sbjct: 80 LNDPGKIVWQHKPKQDASTKAVMCCDVVDRGLAYGAGQIVKKQANGHLLALDAKTGKINW 139 Query: 280 KREL 283 + E+ Sbjct: 140 EVEV 143 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 3/67 (4%) Query: 126 SEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDG-LVLIHTSNGQLQALNEADGAVKWT 184 E Q+ A + + G W A + + G LV T +G L+AL+ DG W Sbjct: 441 KEMGQIRAFDLTTGKAKWTKWEKFAAWGGTLYTKGGLVWYATLDGYLKALDNKDGKELW- 499 Query: 185 VNLDMPS 191 N MPS Sbjct: 500 -NFKMPS 505 >5WLC-LV nrPDB Length = 707 Score = 35.0 bits (79), Expect = 0.051, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 1/66 (1%) Query: 301 QNDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQ 360 QNDR + GG+ T+ R L + N +L VG S L+ +N+E GRF+ Sbjct: 118 QNDRSIQFQNKGGLHYTTRIPKFGRSLVYNKV-NCDLYVGASGNELYRLNLEKGRFLNPF 176 Query: 361 KVDSSG 366 K+D+ G Sbjct: 177 KLDTEG 182 >1H4I-A nrPDB Length = 599 Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust. Identities = 40/171 (23%), Positives = 64/171 (37%), Gaps = 30/171 (17%) Query: 112 SGGVTVSGGHVYIG-SEKAQVYALNTSD-GTVAWQTKVAGEALSRPVVSDGLVLIHTSNG 169 G V G +YI S +AL D GT+ WQ K +R V LV Sbjct: 55 EGAPLVVDGKMYIHTSFPNNTFALGLDDPGTILWQDKPKQNPAARAVACCDLV------- 107 Query: 170 QLQALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQ 229 G W + P+L L+ + +G V+A+ E G+ +W+ Sbjct: 108 -------NRGLAYWPGDGKTPALILKTQL--------------DGNVAALNAETGETVWK 146 Query: 230 QRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWK 280 S + + V V++ L G LTA D+++G+ +W+ Sbjct: 147 VENSDIKVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVKTGEQVWR 197 >6FKW-A nrPDB Length = 577 Score = 32.7 bits (73), Expect = 0.27, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 6/79 (7%) Query: 240 EIDRLSDVDTTPVVV-NGVVFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYL 298 EI V + PVV G+ F +G A+D+++G+++W+++LGS + GN I Sbjct: 459 EIHEHFPVWSGPVVTAGGLAFYGTMDGWFKAVDIKTGKVLWQQKLGSG----IIGNPITF 514 Query: 299 VDQNDRVMALTIDGGVTLW 317 + D+ + + GV W Sbjct: 515 LGP-DKKQYVAVYSGVGGW 532 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/81 (23%), Positives = 32/81 (39%), Gaps = 9/81 (11%) Query: 76 DRAGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALN 135 D G +A GK +W + + + SG V +GG + G+ A++ Sbjct: 441 DYYGAFICYDALKGKRVWEIH---------EHFPVWSGPVVTAGGLAFYGTMDGWFKAVD 491 Query: 136 TSDGTVAWQTKVAGEALSRPV 156 G V WQ K+ + P+ Sbjct: 492 IKTGKVLWQQKLGSGIIGNPI 512 Score = 28.5 bits (62), Expect = 5.0, Method: Compositional matrix adjust. Identities = 57/256 (22%), Positives = 96/256 (37%), Gaps = 33/256 (12%) Query: 66 ALADNVVYAADRAGLVKALNADDGKEIWSVSLAE--KDGWFSKEPALLSGGVT--VSGGH 121 A A+ ++ G + AL+A+ GKE+W + A+ K + P ++ V VSGG Sbjct: 113 AYANGKIFMTTLDGQIIALDANTGKELWKMKHADVTKGETITGAPLVVKDKVLVGVSGGE 172 Query: 122 VYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALN------ 175 + + +V A + + G W G + SD G Sbjct: 173 FGV---RGRVGAYDINTGNRVWLAYSQGPDEEVLLDSDFNKEFPQHGGPGDGTKTWPGEQ 229 Query: 176 -EADGAVKWTVNLDMPSLSL--RGESAPTTAFGAAVVGGDNGRVSAVLMEQ---GQMIWQ 229 + G W P+L L G S P T GGDN + + G+ W Sbjct: 230 WKLGGGTTWGWYSYDPALDLFYYGTSNPGTWNAEQRKGGDNKWSCTIFARRPDTGKARWA 289 Query: 230 QRISQATGSTEIDRLSDVDTTPVVVNG----VVFALAYNGNLTALDLRSGQIM------- 278 +++ S + D ++++ + V G + NG LD R+GQ++ Sbjct: 290 YQMTPWD-SWDYDGVNEMILPDLTVKGKKTPCLVHFDRNGFGYVLDRRTGQLIEAQPFVY 348 Query: 279 --WKRELGSVNDFIVD 292 W +E+ ND V+ Sbjct: 349 VNWAKEISKENDRPVE 364 Score = 28.5 bits (62), Expect = 5.4, Method: Compositional matrix adjust. Identities = 15/59 (25%), Positives = 26/59 (44%) Query: 228 WQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGSV 286 WQ Q + + + V+ NG +F +G + ALD +G+ +WK + V Sbjct: 89 WQYTPVQNSQAVAVACCDVVNRGLAYANGKIFMTTLDGQIIALDANTGKELWKMKHADV 147 >4TQO-B nrPDB Length = 573 Score = 32.3 bits (72), Expect = 0.39, Method: Compositional matrix adjust. Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 9/79 (11%) Query: 79 GLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSD 138 G VKA+NA GK W V ++ A+ G + +G V+ G+ + A +T Sbjct: 446 GQVKAMNAVTGKMEWEV---------PEKFAVWGGTLATAGDLVFYGTLDGFIKARDTRT 496 Query: 139 GTVAWQTKVAGEALSRPVV 157 G + WQ ++ + P+ Sbjct: 497 GELKWQFQLPSGVIGHPIT 515 >5YZG-W nrPDB Length = 579 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 9/56 (16%) Query: 264 NGNLTALDLRSGQIM--WKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLW 317 + + D+RSG+I+ + R LG+VN I VD+N R ++ + D + +W Sbjct: 397 DKKIVQWDIRSGEIVQEYDRHLGAVNT-------IVFVDENRRFVSTSDDKSLRVW 445 >6QDV-o nrPDB Length = 513 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 9/56 (16%) Query: 264 NGNLTALDLRSGQIM--WKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLW 317 + + D+RSG+I+ + R LG+VN I VD+N R ++ + D + +W Sbjct: 331 DKKIVQWDIRSGEIVQEYDRHLGAVNT-------IVFVDENRRFVSTSDDKSLRVW 379 >3N2Z-B nrPDB Length = 446 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 9/58 (15%) Query: 132 YALNTSDGTVAWQTKVAGEALSRPVVSDGLVL---------IHTSNGQLQALNEADGA 180 YA N AW KV + L P VSD L+L + +GQ++ LN ++ A Sbjct: 248 YASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETA 305 >3KLB-A nrPDB Length = 162 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 8/44 (18%) Query: 36 PTVENQFTPT--------TAWSTSVGSGIGNFYSNLHPALADNV 71 PT+ N F + ++TS GSGIGN NLH A D V Sbjct: 94 PTIINTFLESYDFAGKIVVPFATSGGSGIGNCEKNLHKAYPDIV 137 >6DAM-A nrPDB Length = 617 Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust. Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 18/117 (15%) Query: 131 VYALNTSDGTVAWQTKVAGEA-LSRPVVS-----------DGLVLIHTSNGQLQALNEAD 178 VYA++ V W+ +A ++ PV+ DG + + S+ L AL+ Sbjct: 101 VYAIDQKTQAVIWEYTPQQDADVTIPVMCCDTVNRGLAYGDGKIFLQQSDTVLTALDAKT 160 Query: 179 GAVKWTVNLDMPSLSLRGESAPTTAFGAAVVG------GDNGRVSAVLMEQGQMIWQ 229 G W+V P L + AP + G G G ++A + G++ W+ Sbjct: 161 GKRVWSVQNGDPKLGMTNTQAPLVVKDKVITGISGGEFGVRGFLAAYNIRTGELDWK 217 >1PQU-A nrPDB Length = 371 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 43/177 (24%), Positives = 70/177 (39%), Gaps = 21/177 (11%) Query: 193 SLRGESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPV 252 +R ++ PT FGAA+ G + +L E GQ + + G E +++ + P+ Sbjct: 208 KMRADNFPTDNFGAALGGSLIPWIDKLLPETGQTKEEWK-----GYAETNKILGLSDNPI 262 Query: 253 VVNGVVFAL-AYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMAL--- 308 V+G+ + A N A ++ + + L + I N V ND+ + L Sbjct: 263 PVDGLCVRIGALRCNSQAFTIKLKKDL---PLEEIEQIIASHNEWVKVIPNDKEITLREL 319 Query: 309 ---TIDGGVTLWTQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKV 362 + G TL L +L P Y VGD L W E R + +Q V Sbjct: 320 TPAKVTG--TLSVPVGRLRKLAMGPE-YLAAFTVGDQ---LLWGAAEPVRRILKQLV 370 >5XM3-A nrPDB Length = 627 Score = 27.7 bits (60), Expect = 8.6, Method: Compositional matrix adjust. Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 10/73 (13%) Query: 213 NGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDL 272 +G+V A G+ W++ +++ S T G+VF +G + A D Sbjct: 483 SGQVKAYNAITGEFAWEK----------MEKFSVWGGTTATEGGLVFYGTLDGFIKARDA 532 Query: 273 RSGQIMWKRELGS 285 +G+++WK +L S Sbjct: 533 DTGKLLWKFKLPS 545 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4PK1-A nrPDB 538 e-153 3P1L-A nrPDB 538 e-153 4HDJ-A nrPDB 424 e-119 4IMM-A nrPDB 360 e-100 1FLG-A nrPDB 156 2e-38 Sequences not found previously or not previously below threshold: 1KV9-A nrPDB 79 3e-15 1YIQ-A nrPDB 74 9e-14 1KB0-A nrPDB 73 2e-13 6FKW-A nrPDB 62 4e-10 2AD6-A nrPDB 49 2e-06 1LRW-A nrPDB 49 3e-06 2D0V-A nrPDB 49 4e-06 1H4I-A nrPDB 47 1e-05 4TQO-B nrPDB 47 2e-05 5XM3-A nrPDB 45 6e-05 6DAM-A nrPDB 42 4e-04 2OAS-A nrPDB 31 0.94 5JKJ-A nrPDB 31 1.1 3NDO-A nrPDB 30 1.8 3G9W-A nrPDB 30 2.1 1Q90-A nrPDB 28 9.0 >4PK1-A nrPDB Length = 645 Score = 538 bits (1387), Expect = e-153, Method: Composition-based stats. Identities = 372/372 (100%), Positives = 372/372 (100%) Query: 21 SLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGL 80 SLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGL Sbjct: 274 SLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGL 333 Query: 81 VKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGT 140 VKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGT Sbjct: 334 VKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGT 393 Query: 141 VAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAP 200 VAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAP Sbjct: 394 VAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAP 453 Query: 201 TTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFA 260 TTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFA Sbjct: 454 TTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFA 513 Query: 261 LAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQS 320 LAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQS Sbjct: 514 LAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQS 573 Query: 321 DLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLI 380 DLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLI Sbjct: 574 DLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLI 633 Query: 381 QAKDGTVYSITR 392 QAKDGTVYSITR Sbjct: 634 QAKDGTVYSITR 645 >3P1L-A nrPDB Length = 393 Score = 538 bits (1386), Expect = e-153, Method: Composition-based stats. Identities = 373/375 (99%), Positives = 373/375 (99%) Query: 18 SGCSLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADR 77 S SLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADR Sbjct: 19 SHMSLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADR 78 Query: 78 AGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTS 137 AGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTS Sbjct: 79 AGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTS 138 Query: 138 DGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGE 197 DGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGE Sbjct: 139 DGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGE 198 Query: 198 SAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGV 257 SAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGV Sbjct: 199 SAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGV 258 Query: 258 VFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLW 317 VFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLW Sbjct: 259 VFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLW 318 Query: 318 TQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGK 377 TQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGK Sbjct: 319 TQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGK 378 Query: 378 LLIQAKDGTVYSITR 392 LLIQAKDGTVYSITR Sbjct: 379 LLIQAKDGTVYSITR 393 >4HDJ-A nrPDB Length = 367 Score = 424 bits (1089), Expect = e-119, Method: Composition-based stats. Identities = 109/357 (30%), Positives = 179/357 (50%), Gaps = 10/357 (2%) Query: 35 LPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWS 94 L + + + WS SVG G G+ Y+ L PA+ + +YAA G V A+ + G +W Sbjct: 17 LTDFKEEVVLSKQWSRSVGDGQGDLYNLLEPAVDGSTIYAASAEGRVMAIQRETGDVLWK 76 Query: 95 VSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSR 154 L L T+ G V AL+ + G W +V E LS Sbjct: 77 KDLERPVSGGVGVGYGLVLVGTLRG----------DVIALDEATGKKKWTKRVNSEVLSA 126 Query: 155 PVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVGGDNG 214 P + +V++ T + +L L+ A G +W +P L+LRG AP A A+ G +G Sbjct: 127 PATNGDVVVVQTQDDKLIGLDAASGDQRWIYESTVPVLTLRGTGAPLIAGNMALAGLASG 186 Query: 215 RVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRS 274 +V AV +++G IW+QR++ G +E+DR+ D+D ++ ++ ++Y G ALD+ S Sbjct: 187 KVVAVDVQRGLPIWEQRVAIPQGRSELDRVVDIDGGLLLSGDTLYVVSYQGRAAALDVNS 246 Query: 275 GQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYN 334 G+++W+RE S IY+ + V L G +LW L R L++P +++ Sbjct: 247 GRLLWQREASSYVGVAEGFGNIYVSQASGSVEGLDSRGASSLWNNDALARRQLSAPAVFS 306 Query: 335 GNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSIT 391 N+VVGD EGY+H ++ DGRFV +++VDS G + P+ + + G + + T Sbjct: 307 SNVVVGDLEGYVHLLSQVDGRFVGRERVDSDGVRVRPLVVGSWMYVFGNGGKLVAYT 363 >4IMM-A nrPDB Length = 399 Score = 360 bits (923), Expect = e-100, Method: Composition-based stats. Identities = 93/326 (28%), Positives = 160/326 (49%), Gaps = 19/326 (5%) Query: 65 PALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTV--SGGHV 122 LAD ++ AA R+G+V + E W +++GGV + G Sbjct: 78 APLADGMI-AASRSGIVSGY------------MGESIAWQYNAEDVITGGVGIDDQGSVA 124 Query: 123 YIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVK 182 IG+ ++ AL+ G W ++A +L+ ++S V++ T++G + L+ GA Sbjct: 125 VIGTRSGKLIALDARTGAARWVVELASSSLAPALISGDKVIVITNSGTIFGLDINSGATV 184 Query: 183 WTVNLDMPSLSLRGESAPTTAFGAAV-VGGDNGRVSAVLMEQGQMIWQQRISQATGSTEI 241 W +P+ S+RG + P V +GG +GR+ A+ G +W +R+ A GS EI Sbjct: 185 WQYATQVPNTSVRGMAKPLALDARTVLIGGADGRIHALDTMTGAPVWTRRVGLAMGSGEI 244 Query: 242 DRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQ 301 D+L D+D TP VV+ ++A +Y+G L D+ +G+ M+ EL S + + Sbjct: 245 DQLRDIDGTPTVVDHYLYAASYSGQLAGFDMTTGRTMFVSELSSTKKLTTLADAVIGSST 304 Query: 302 NDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQK 361 + V+A G LW DL +R LT+PV + VGD++G +H +N G+ ++ + Sbjct: 305 DGDVVAFNRMTGEKLWENHDLKYRGLTNPVTIGTYIAVGDADGVVHILN-HQGQIIS--R 361 Query: 362 VDSSGFQTEPVAADGKLLIQAKDGTV 387 ++ G T + +L Q+ DG V Sbjct: 362 ANTKGALTNLTVINNRLYAQSADGVV 387 >1FLG-A nrPDB Length = 582 Score = 156 bits (393), Expect = 2e-38, Method: Composition-based stats. Identities = 59/231 (25%), Positives = 88/231 (38%), Gaps = 42/231 (18%) Query: 31 KMSPLPTV--ENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADD 88 + SPL V +N F T AWS S G + ++D V+Y + AL+A Sbjct: 29 RWSPLKQVNADNVFKLTPAWSYSFGDEKQRGQES-QAIVSDGVIYVTASYSRLFALDAKT 87 Query: 89 GKEIWSVSLAEKDGWFSKEPA--LLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTK 146 GK +W+ + D P +++ G + G V+ G+ A V ALN + G V W+ K Sbjct: 88 GKRLWTYNHRLPD---DIRPCCDVVNRGAAIYGDKVFFGTLDASVVALNKNTGKVVWKKK 144 Query: 147 VAGEAL------SRPVVSDG----LVLIHTSN-------GQLQALNEADGAVKWTVNLDM 189 A + +V DG ++LIH S+ G+L A + G W Sbjct: 145 FADHGAGYTMTGAPTIVKDGKTGKVLLIHGSSGDEFGVVGRLFARDPDTGEEIWM----- 199 Query: 190 PSLSLRGESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTE 240 P G NG+ S V + W + TG E Sbjct: 200 ---------RPFVEGHM---GRLNGKDSTVTGDVKAPSWPDDRNSPTGKVE 238 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 34/197 (17%), Positives = 68/197 (34%), Gaps = 38/197 (19%) Query: 215 RVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRS 274 +V+A + + W + ++ +V +GV++ A L ALD ++ Sbjct: 35 QVNADNVFKLTPAWSYSFGDEKQRGQ-------ESQAIVSDGVIYVTASYSRLFALDAKT 87 Query: 275 GQIMW---------KRELGSVN--DFIVDGNRIYLVDQNDRVMALTIDGGVTLWT----Q 319 G+ +W R V + G++++ + V+AL + G +W Sbjct: 88 GKRLWTYNHRLPDDIRPCCDVVNRGAAIYGDKVFFGTLDASVVALNKNTGKVVWKKKFAD 147 Query: 320 SDLLHRLLTSPVLY----NGNLVV-----GDSEGYLHWINVEDGRFVAQQKVDSSGFQTE 370 + + +P + G +++ GD G + GR A+ Sbjct: 148 HGAGYTMTGAPTIVKDGKTGKVLLIHGSSGDEFGVV-------GRLFARDPDTGEEIWMR 200 Query: 371 PVAADGKLLIQAKDGTV 387 P + KD TV Sbjct: 201 PFVEGHMGRLNGKDSTV 217 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 31/82 (37%), Gaps = 9/82 (10%) Query: 76 DRAGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALN 135 D G ++A++ GK +W L +G + +G V+ G+ A + Sbjct: 463 DHVGSLRAMDPVSGKVVWEHKEHLP---------LWAGVLATAGNLVFTGTGDGYFKAFD 513 Query: 136 TSDGTVAWQTKVAGEALSRPVV 157 G W+ + +S P+ Sbjct: 514 AKSGKELWKFQTGSGIVSPPIT 535 Score = 32.8 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 29/72 (40%), Gaps = 10/72 (13%) Query: 214 GRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLR 273 G + A+ G+++W+ + + +VF +G A D + Sbjct: 466 GSLRAMDPVSGKVVWEHKEHLPLWA----------GVLATAGNLVFTGTGDGYFKAFDAK 515 Query: 274 SGQIMWKRELGS 285 SG+ +WK + GS Sbjct: 516 SGKELWKFQTGS 527 Score = 29.0 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 3/56 (5%) Query: 265 GNLTALDLRSGQIMW--KRELGSVND-FIVDGNRIYLVDQNDRVMALTIDGGVTLW 317 G+L A+D SG+++W K L GN ++ + A G LW Sbjct: 466 GSLRAMDPVSGKVVWEHKEHLPLWAGVLATAGNLVFTGTGDGYFKAFDAKSGKELW 521 >1KV9-A nrPDB Length = 668 Score = 79.4 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 36/171 (21%), Positives = 65/171 (38%), Gaps = 17/171 (9%) Query: 31 KMSPLPTVE--NQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADD 88 + SPL ++ N + AW + + G P D V+Y + V A++A Sbjct: 29 RFSPLKQIDASNVRSLGLAWYMDLDNTRG---LEATPLFHDGVIYTSMSWSRVIAVDAAS 85 Query: 89 GKEIWSVSLA-EKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKV 147 GKE+W K + ++ GV + G VY+G+ ++ AL+ G W + Sbjct: 86 GKELWRYDPEVAKVKARTSCCDAVNRGVALWGDKVYVGTLDGRLIALDAKTGKAIWSQQT 145 Query: 148 AGEAL------SRPVVSDGLVLIHTSN-----GQLQALNEADGAVKWTVNL 187 A + VV +++ + G + A + G + W Sbjct: 146 TDPAKPYSITGAPRVVKGKVIIGNGGAEYGVRGFVSAYDADTGKLAWRFYT 196 Score = 59.0 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 58/286 (20%), Positives = 103/286 (36%), Gaps = 55/286 (19%) Query: 67 LADNVVYAADRAGLVKALNADDGKEI---WSVSLAEKDGWFSKEPALLSGGVTVSGGHVY 123 L+ YA R +K ++A + + + W + L G L G +Y Sbjct: 19 LSHGRTYAEQRFSPLKQIDASNVRSLGLAWYMDLDNTRG--------LEATPLFHDGVIY 70 Query: 124 IGSEKAQVYALNTSDGTVAW-----QTKVAGEALSRPVVS------DGLVLIHTSNGQLQ 172 ++V A++ + G W KV V+ V + T +G+L Sbjct: 71 TSMSWSRVIAVDAASGKELWRYDPEVAKVKARTSCCDAVNRGVALWGDKVYVGTLDGRLI 130 Query: 173 ALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVG------GDNGRVSAVLMEQGQM 226 AL+ G W+ P+ AP G ++G G G VSA + G++ Sbjct: 131 ALDAKTGKAIWSQQTTDPAKPYSITGAPRVVKGKVIIGNGGAEYGVRGFVSAYDADTGKL 190 Query: 227 IWQ--------------QRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDL 272 W+ + +A + + D+ + V + ++AY+ L L + Sbjct: 191 AWRFYTVPGDPALPYEHPELREAAKTWQGDQYWKLGGGGTVWD----SMAYDPELDLLYV 246 Query: 273 RSGQ-IMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLW 317 +G W RE+ S G+ +YL ++A+ D G W Sbjct: 247 GTGNGSPWNREVRSPGG----GDNLYLSS----ILAIRPDTGKLAW 284 Score = 49.0 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 55/119 (46%), Gaps = 17/119 (14%) Query: 240 EIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWK--RELGSVN---------- 287 ++D ++ TP+ +GV++ + A+D SG+ +W+ E+ V Sbjct: 51 DLDNTRGLEATPLFHDGVIYTSMSWSRVIAVDAASGKELWRYDPEVAKVKARTSCCDAVN 110 Query: 288 -DFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQS----DLLHRLLTSPVLYNGNLVVGD 341 + G+++Y+ + R++AL G +W+Q + + +P + G +++G+ Sbjct: 111 RGVALWGDKVYVGTLDGRLIALDAKTGKAIWSQQTTDPAKPYSITGAPRVVKGKVIIGN 169 Score = 31.7 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 48/269 (17%), Positives = 75/269 (27%), Gaps = 39/269 (14%) Query: 81 VKALNADDGKEIWSVSLAEKDGWF--------------SKEPALLSGGVTVSGGHVYIGS 126 + A+ D GK W + D W +P + +G + Sbjct: 272 ILAIRPDTGKLAWHYQVTPGDSWDFTATQQITLAELNIDGKPRKVLMQAPKNGFFYVLDR 331 Query: 127 EKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVN 186 ++ + G V W KV A RPV + G + + GA W Sbjct: 332 TNGKLISA-EKFGKVTWAEKV-DLATGRPVEAPG---VRYEKEPIVMWPSPFGAHNWHSM 386 Query: 187 LDMPSLSL------------RGESAPTT---AFGAAVVGGDNGRVSAVLMEQGQMIWQQR 231 P L R E AF A D V A ++ + W Sbjct: 387 SFNPGTGLVYIPYQEVPGVYRNEGKDFVTRKAFNTAAGFADATDVPAAVVSGALLAWDPV 446 Query: 232 ISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGSVNDFI- 290 +A + T +VF G + A G+ +W+ E S Sbjct: 447 KQKAAWKVPYPTHWN-GGTLSTAGNLVFQGTAAGQMHAYSADKGEALWQFEAQSGIVAAP 505 Query: 291 ---VDGNRIYLVDQNDRVMALTIDGGVTL 316 R Y+ T+ GG ++ Sbjct: 506 MTFELAGRQYVAIMAGWGGVATLTGGESM 534 >1YIQ-A nrPDB Length = 689 Score = 74.4 bits (181), Expect = 9e-14, Method: Composition-based stats. Identities = 44/201 (21%), Positives = 70/201 (34%), Gaps = 20/201 (9%) Query: 28 DVVKMSPLPTV--ENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALN 85 D + SPL + +N AWS + G P + D V+Y +V AL+ Sbjct: 30 DEQRYSPLKQISDQNVGQLGLAWSYKLDLDRG---VEATPIVVDGVMYTTGPFSVVYALD 86 Query: 86 ADDGKEIWSVSLAEKDGWFSKEPA--LLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAW 143 A DG+ IW + D + E ++ GV V G VY+G ++ A++ G AW Sbjct: 87 ARDGRLIWKYD-PQSDRHRAGEACCDAVNRGVAVWKGKVYVGVLDGRLEAIDAKTGQRAW 145 Query: 144 QTKVAGE-------ALSRPVVSDGLVLIHTSN-----GQLQALNEADGAVKWTVNLDMPS 191 + + VV+ +V+ + G + A + G W Sbjct: 146 SVDTRADHKRSYTITGAPRVVNGKVVIGNGGAEFGVRGYVTAYDAETGKEAWRFYTVPGD 205 Query: 192 LSLRGESAPTTAFGAAVVGGD 212 L E G Sbjct: 206 PKLPPEGKGMEIAAKTWFGDA 226 Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 32/142 (22%), Positives = 61/142 (42%), Gaps = 24/142 (16%) Query: 238 STEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGS------------ 285 S ++D V+ TP+VV+GV++ + ALD R G+++WK + S Sbjct: 53 SYKLDLDRGVEATPIVVDGVMYTTGPFSVVYALDARDGRLIWKYDPQSDRHRAGEACCDA 112 Query: 286 -VNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWT-----QSDLLHRLLTSPVLYNGNLVV 339 V ++Y+ + R+ A+ G W+ + + +P + NG +V+ Sbjct: 113 VNRGVAVWKGKVYVGVLDGRLEAIDAKTGQRAWSVDTRADHKRSYTITGAPRVVNGKVVI 172 Query: 340 GD------SEGYLHWINVEDGR 355 G+ GY+ + E G+ Sbjct: 173 GNGGAEFGVRGYVTAYDAETGK 194 Score = 44.8 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 35/142 (24%), Positives = 53/142 (37%), Gaps = 21/142 (14%) Query: 153 SRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAV---- 208 + P+V DG++ + AL+ DG + W + S R A A V Sbjct: 64 ATPIVVDGVMYTTGPFSVVYALDARDGRLIWKYDPQ--SDRHRAGEACCDAVNRGVAVWK 121 Query: 209 ----VGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFA---- 260 VG +GR+ A+ + GQ W + R + P VVNG V Sbjct: 122 GKVYVGVLDGRLEAIDAKTGQRAWS-----VDTRADHKRSYTITGAPRVVNGKVVIGNGG 176 Query: 261 --LAYNGNLTALDLRSGQIMWK 280 G +TA D +G+ W+ Sbjct: 177 AEFGVRGYVTAYDAETGKEAWR 198 Score = 41.3 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 9/100 (9%) Query: 260 ALAYNGNLTALDLRSGQIMWKRELGSVND---FIVDGNRIYLVDQNDRVMALTIDGGVTL 316 A +++G L A D Q W+ ++ + GN ++ + RV+A D G L Sbjct: 450 AKSWSGKLIAWDPVKQQAAWEVPYVTIFNGGTLSTAGNLVFEGSADGRVIAYAADTGEKL 509 Query: 317 WTQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRF 356 W Q ++ +PV Y+ D E Y+ ++ G F Sbjct: 510 WEQPA-ASGVMAAPVTYSV-----DGEQYVTFMAGWGGAF 543 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 49/125 (39%), Gaps = 6/125 (4%) Query: 151 ALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVG 210 + L + + +G+L A + W ++P +++ +TA G Sbjct: 437 GMMPEGAEGLLEMAKSWSGKLIAWDPVKQQAAW----EVPYVTIFNGGTLSTAGNLVFEG 492 Query: 211 GDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTAL 270 +GRV A + G+ +W+Q A+G VD V + A++ AL Sbjct: 493 SADGRVIAYAADTGEKLWEQ--PAASGVMAAPVTYSVDGEQYVTFMAGWGGAFSTFAGAL 550 Query: 271 DLRSG 275 LR+G Sbjct: 551 SLRAG 555 Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 1/82 (1%) Query: 77 RAGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGG-VTVSGGHVYIGSEKAQVYALN 135 GL++ + GK I + ++ W + +GG ++ +G V+ GS +V A Sbjct: 443 AEGLLEMAKSWSGKLIAWDPVKQQAAWEVPYVTIFNGGTLSTAGNLVFEGSADGRVIAYA 502 Query: 136 TSDGTVAWQTKVAGEALSRPVV 157 G W+ A ++ PV Sbjct: 503 ADTGEKLWEQPAASGVMAAPVT 524 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 10/27 (37%), Positives = 15/27 (55%) Query: 68 ADNVVYAADRAGLVKALNADDGKEIWS 94 A N+V+ G V A AD G+++W Sbjct: 485 AGNLVFEGSADGRVIAYAADTGEKLWE 511 >1KB0-A nrPDB Length = 677 Score = 73.3 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 40/170 (23%), Positives = 69/170 (40%), Gaps = 18/170 (10%) Query: 31 KMSPLPTVE--NQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADD 88 + S L + N AWS ++ S G P + D ++Y + +V A++ Sbjct: 40 RYSRLDQINAANVKDLGLAWSYNLESTRG---VEATPVVVDGIMYVSASWSVVHAIDTRT 96 Query: 89 GKEIWSVSLA-EKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAW-QTK 146 G IW+ ++ F +++ GV + G VY+G+ ++ AL+ + G W Q Sbjct: 97 GNRIWTYDPQIDRSTGFKGCCDVVNRGVALWKGKVYVGAWDGRLIALDAATGKEVWHQNT 156 Query: 147 VAGEALS-----RPVVSDGLVLI------HTSNGQLQALNEADGAVKWTV 185 G+ S P V G V+I + G + A + G KW Sbjct: 157 FEGQKGSLTITGAPRVFKGKVIIGNGGAEYGVRGYITAYDAETGERKWRW 206 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 43/206 (20%), Positives = 72/206 (34%), Gaps = 20/206 (9%) Query: 84 LNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAW 143 + DG I + + D + S Q+ A N D +AW Sbjct: 11 VQRVDGDFIRANAARTPDWPTIGVDYAETR-----------YSRLDQINAANVKDLGLAW 59 Query: 144 QTKVAGE--ALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMP-SLSLRGESAP 200 + + PVV DG++ + S + A++ G WT + + S +G Sbjct: 60 SYNLESTRGVEATPVVVDGIMYVSASWSVVHAIDTRTGNRIWTYDPQIDRSTGFKGCCDV 119 Query: 201 TTAF-----GAAVVGGDNGRVSAVLMEQGQMIWQQRISQAT-GSTEIDRLSDVDTTPVVV 254 G VG +GR+ A+ G+ +W Q + GS I V V++ Sbjct: 120 VNRGVALWKGKVYVGAWDGRLIALDAATGKEVWHQNTFEGQKGSLTITGAPRVFKGKVII 179 Query: 255 NGVVFALAYNGNLTALDLRSGQIMWK 280 G +TA D +G+ W+ Sbjct: 180 GNGGAEYGVRGYITAYDAETGERKWR 205 Score = 44.8 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 28/142 (19%), Positives = 60/142 (42%), Gaps = 24/142 (16%) Query: 238 STEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELG------------- 284 S ++ V+ TPVVV+G+++ A + A+D R+G +W + Sbjct: 60 SYNLESTRGVEATPVVVDGIMYVSASWSVVHAIDTRTGNRIWTYDPQIDRSTGFKGCCDV 119 Query: 285 SVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSDLLHRLLT-----SPVLYNGNLVV 339 + ++Y+ + R++AL G +W Q+ + + +P ++ G +++ Sbjct: 120 VNRGVALWKGKVYVGAWDGRLIALDAATGKEVWHQNTFEGQKGSLTITGAPRVFKGKVII 179 Query: 340 GD------SEGYLHWINVEDGR 355 G+ GY+ + E G Sbjct: 180 GNGGAEYGVRGYITAYDAETGE 201 Score = 37.5 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 28/79 (35%), Gaps = 9/79 (11%) Query: 79 GLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSD 138 G + A + K WSV G +T +G V+ G+ ++ A + + Sbjct: 457 GRLLAWDPVAQKAAWSVEHVSPWNG---------GTLTTAGNVVFQGTADGRLVAYHAAT 507 Query: 139 GTVAWQTKVAGEALSRPVV 157 G W+ ++ P Sbjct: 508 GEKLWEAPTGTGVVAAPST 526 Score = 31.7 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 3/57 (5%) Query: 265 GNLTALDLRSGQIMWKRE-LGSVND--FIVDGNRIYLVDQNDRVMALTIDGGVTLWT 318 G L A D + + W E + N GN ++ + R++A G LW Sbjct: 457 GRLLAWDPVAQKAAWSVEHVSPWNGGTLTTAGNVVFQGTADGRLVAYHAATGEKLWE 513 Score = 27.4 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 38/140 (27%), Gaps = 29/140 (20%) Query: 180 AVKWTVNLDMPSLSLRGESAPTTAFGAAVVGGDN--GRVSAVLMEQGQMIWQ-QRISQAT 236 KW N P G T F A GR+ A + W + +S Sbjct: 421 DKKWEFNQAGPGKPQSGTGWNTAKFFNAEPPKSKPFGRLLAWDPVAQKAAWSVEHVSPWN 480 Query: 237 GSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGS----------- 285 G T VVF +G L A +G+ +W+ G+ Sbjct: 481 G-----------GTLTTAGNVVFQGTADGRLVAYHAATGEKLWEAPTGTGVVAAPSTYMV 529 Query: 286 ----VNDFIVDGNRIYLVDQ 301 V +Y + Sbjct: 530 DGRQYVSVAVGWGGVYGLAA 549 >6FKW-A nrPDB Length = 577 Score = 62.1 bits (149), Expect = 4e-10, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 61/177 (34%), Gaps = 20/177 (11%) Query: 31 KMSPLPTV--ENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRA-GLVKALN-- 85 + S L + +N AWS S G+ G P + +Y V AL+ Sbjct: 25 RYSELNQINTKNVSRLRLAWSFSTGALRG---HEGGPLVVGTTMYVHSAYPNHVYALDLT 81 Query: 86 ADDGKEIWSVS-LAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQ 144 W + + +++ G+ + G +++ + Q+ AL+ + G W+ Sbjct: 82 QKPYAIKWQYTPVQNSQAVAVACCDVVNRGLAYANGKIFMTTLDGQIIALDANTGKELWK 141 Query: 145 TKVAG-----EALSRPVVSDGLVLIHTSN------GQLQALNEADGAVKWTVNLDMP 190 K A P+V VL+ S G++ A + G W P Sbjct: 142 MKHADVTKGETITGAPLVVKDKVLVGVSGGEFGVRGRVGAYDINTGNRVWLAYSQGP 198 Score = 41.7 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 41/110 (37%), Gaps = 15/110 (13%) Query: 54 SGIGNFYSNLHPALADNVVYAA------DRAGLVKALNADDGKEIWSVSLAEKDGWFSKE 107 G+ Y+ P + NV+ + D G +A GK +W + Sbjct: 413 EGVEATYTAGAPYVGANVLMYSGHEGKDDYYGAFICYDALKGKRVWEIHEHFP------- 465 Query: 108 PALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVV 157 + SG V +GG + G+ A++ G V WQ K+ + P+ Sbjct: 466 --VWSGPVVTAGGLAFYGTMDGWFKAVDIKTGKVLWQQKLGSGIIGNPIT 513 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 35/92 (38%), Gaps = 10/92 (10%) Query: 148 AGEALSRPVVSDGLVLIHTSNGQ------LQALNEADGAVKWTVNLDMPSLSLRGESAPT 201 A P V +++ G+ + G W ++ P S Sbjct: 417 ATYTAGAPYVGANVLMYSGHEGKDDYYGAFICYDALKGKRVWEIHEHFPVWS----GPVV 472 Query: 202 TAFGAAVVGGDNGRVSAVLMEQGQMIWQQRIS 233 TA G A G +G AV ++ G+++WQQ++ Sbjct: 473 TAGGLAFYGTMDGWFKAVDIKTGKVLWQQKLG 504 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 50/293 (17%), Positives = 91/293 (31%), Gaps = 64/293 (21%) Query: 44 PTTAWSTSVGSGIGNFYSNLHPALA--------DNVVYAADRAG-------LVKALNADD 88 P W +G G + + PAL A R G + A D Sbjct: 226 PGEQWK--LGGGTTWGWYSYDPALDLFYYGTSNPGTWNAEQRKGGDNKWSCTIFARRPDT 283 Query: 89 GKEIWSVSLAEKDGW-FSKEPALLSGGVTVSGGH---VYIGSEKAQVYALNTSDGT---- 140 GK W+ + D W + ++ +TV G + Y L+ G Sbjct: 284 GKARWAYQMTPWDSWDYDGVNEMILPDLTVKGKKTPCLVHFDRNGFGYVLDRRTGQLIEA 343 Query: 141 -----VAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLD------- 188 V W +++ E RPV + + N G + Sbjct: 344 QPFVYVNWAKEISKEN-DRPVEIPEKRTKQGVDTKGICPNSMGGKDQQPAAFSPQTGLFY 402 Query: 189 MPSLSL----------RGESAPTTAFGAAVVGGDNGR------VSAVLMEQGQMIWQQRI 232 +P+ ++ AP + G G+ +G+ +W+ Sbjct: 403 VPTNNMCMNYEGVEATYTAGAPYVGANVLMYSGHEGKDDYYGAFICYDALKGKRVWEIHE 462 Query: 233 SQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGS 285 S + V G+ F +G A+D+++G+++W+++LGS Sbjct: 463 HFPVWSGPV----------VTAGGLAFYGTMDGWFKAVDIKTGKVLWQQKLGS 505 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 52/142 (36%), Gaps = 17/142 (11%) Query: 193 SLRG-ESAPTTAFGAAVVGGD-NGRVSAVLMEQG--QMIWQQRISQATGSTEIDRLSDVD 248 +LRG E P V V A+ + Q + WQ Q + + + V+ Sbjct: 50 ALRGHEGGPLVVGTTMYVHSAYPNHVYALDLTQKPYAIKWQYTPVQNSQAVAVACCDVVN 109 Query: 249 TTPVVVNGVVFALAYNGNLTALDLRSGQIMWK-RELGSVNDFIVDGNRIYLVDQ------ 301 NG +F +G + ALD +G+ +WK + + G + + D+ Sbjct: 110 RGLAYANGKIFMTTLDGQIIALDANTGKELWKMKHADVTKGETITGAPLVVKDKVLVGVS 169 Query: 302 ------NDRVMALTIDGGVTLW 317 RV A I+ G +W Sbjct: 170 GGEFGVRGRVGAYDINTGNRVW 191 >2AD6-A nrPDB Length = 571 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 35/177 (19%), Positives = 62/177 (35%), Gaps = 15/177 (8%) Query: 33 SPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRA-GLVKALNADD-GK 90 SPL + + S +G+ N + P + +++Y ALN +D GK Sbjct: 27 SPLAQINKSNVKNVKAAWSFSTGVLNGHEGA-PLVIGDMMYVHSAFPNNTYALNLNDPGK 85 Query: 91 EIWSVSLAEKDGWFSKEPA-LLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQT---- 145 +W + + ++ G+ G + + AL+ G + W+ Sbjct: 86 IVWQHKPKQDASTKAVMCCDVVDRGLAYGAGQIVKKQANGHLLALDAKTGKINWEVEVCD 145 Query: 146 -KVAGEALSRPVVSDGLVLIHTSN------GQLQALNEADGAVKWTVNLDMPSLSLR 195 KV P V+ VL+ S G + A + G +KW S+R Sbjct: 146 PKVGSTLTQAPFVAKDTVLMGCSGAELGVRGAVNAFDLKTGELKWRAFATGSDDSVR 202 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 38/211 (18%), Positives = 72/211 (34%), Gaps = 14/211 (6%) Query: 129 AQVYALNTSDGTVAWQ--TKVAGEALSRPVVSDGLVLIHTS-NGQLQALNEAD-GAVKWT 184 AQ+ N + AW T V P+V ++ +H++ ALN D G + W Sbjct: 30 AQINKSNVKNVKAAWSFSTGVLNGHEGAPLVIGDMMYVHSAFPNNTYALNLNDPGKIVWQ 89 Query: 185 VNLDMPSLSLRGESAPTTAFGAAVVGG------DNGRVSAVLMEQGQMIWQQRISQATGS 238 + + G A G NG + A+ + G++ W+ + Sbjct: 90 HKPKQDASTKAVMCCDVVDRGLAYGAGQIVKKQANGHLLALDAKTGKINWEVEVCDPKVG 149 Query: 239 TEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYL 298 + + + V V++ L G + A DL++G++ W+ +D + Sbjct: 150 STLTQAPFVAKDTVLMGCSGAELGVRGAVNAFDLKTGELKWRAFATGSDDSVRLAKDFNS 209 Query: 299 VDQNDRVMALTIDGGVTLWTQSDLLHRLLTS 329 + + L G W T+ Sbjct: 210 ANPHYGQFGL----GTKTWEGDAWKIGGGTN 236 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 8/78 (10%) Query: 127 EKAQVYALNTSDGTVAWQT--KVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWT 184 E Q+ A + + G W K A GLV T +G L+AL+ DG W Sbjct: 442 EMGQIRAFDLTTGKAKWTKWEKFAAWG-GTLYTKGGLVWYATLDGYLKALDNKDGKELW- 499 Query: 185 VNLDMPSLSLRGESAPTT 202 N MPS G +P T Sbjct: 500 -NFKMPS---GGIGSPMT 513 Score = 36.7 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 30/79 (37%), Gaps = 9/79 (11%) Query: 79 GLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSD 138 G ++A + GK W+ + W G + GG V+ + + AL+ D Sbjct: 444 GQIRAFDLTTGKAKWTK-WEKFAAWG--------GTLYTKGGLVWYATLDGYLKALDNKD 494 Query: 139 GTVAWQTKVAGEALSRPVV 157 G W K+ + P+ Sbjct: 495 GKELWNFKMPSGGIGSPMT 513 Score = 35.1 bits (79), Expect = 0.049, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 33/89 (37%), Gaps = 6/89 (6%) Query: 265 GNLTALDLRSGQ---IMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSD 321 G + A DL +G+ W++ G ++ + + AL G LW Sbjct: 444 GQIRAFDLTTGKAKWTKWEKFAAWGGTLYTKGGLVWYATLDGYLKALDNKDGKELW-NFK 502 Query: 322 LLHRLLTSPVLYN--GNLVVGDSEGYLHW 348 + + SP+ Y+ G +G G W Sbjct: 503 MPSGGIGSPMTYSFKGKQYIGSMYGVGGW 531 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 31/72 (43%), Gaps = 10/72 (13%) Query: 214 GRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLR 273 G++ A + G+ W + ++ + T G+V+ +G L ALD + Sbjct: 444 GQIRAFDLTTGKAKWTK----------WEKFAAWGGTLYTKGGLVWYATLDGYLKALDNK 493 Query: 274 SGQIMWKRELGS 285 G+ +W ++ S Sbjct: 494 DGKELWNFKMPS 505 Score = 28.2 bits (61), Expect = 6.3, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 18/29 (62%) Query: 69 DNVVYAADRAGLVKALNADDGKEIWSVSL 97 +V+ A G +KAL+ DGKE+W+ + Sbjct: 475 GGLVWYATLDGYLKALDNKDGKELWNFKM 503 >1LRW-A nrPDB Length = 600 Score = 49.4 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 33/184 (17%), Positives = 58/184 (31%), Gaps = 23/184 (12%) Query: 32 MSPLPTV--ENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALN-ADD 88 S + + EN AWS S G + + + + D + AL+ + Sbjct: 26 YSEMTDINKENVKQLRPAWSFSTG--VLHGHEGTPLVVGDRMFIHTPFPNTTFALDLNEP 83 Query: 89 GKEIWS-VSLAEKDGWFSKEPALLSGGVTVSGG------HVYIGSEKAQVYALNTSDGTV 141 GK +W +++ G+ G ++ + A++ G Sbjct: 84 GKILWQNKPKQNPTARTVACCDVVNRGLAYWPGDDQVKPLIFRTQLDGHIVAMDAETGET 143 Query: 142 AWQ-----TKVAGEALSRPVVSDGLVLIHTSN------GQLQALNEADGAVKWTVNLDMP 190 W KV P V LVL+ +S G + A + G ++W P Sbjct: 144 RWIMENSDIKVGSTLTIAPYVIKDLVLVGSSGAELGVRGYVTAYDVKSGEMRWRAFATGP 203 Query: 191 SLSL 194 L Sbjct: 204 DEEL 207 Score = 36.7 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 54/289 (18%), Positives = 98/289 (33%), Gaps = 56/289 (19%) Query: 73 YAADRAGLVKALNADDGKEI---WSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSE-K 128 Y A + +N ++ K++ WS S P ++ G ++I + Sbjct: 21 YNAQNYSEMTDINKENVKQLRPAWSFSTGV-LHGHEGTPLVV-------GDRMFIHTPFP 72 Query: 129 AQVYALNTSD-GTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNL 187 +AL+ ++ G + WQ K +R V +V G W + Sbjct: 73 NTTFALDLNEPGKILWQNKPKQNPTARTVACCDVV--------------NRGLAYWPGDD 118 Query: 188 DMPSLSLRGESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDV 247 + L R + +G + A+ E G+ W S + + V Sbjct: 119 QVKPLIFRTQ--------------LDGHIVAMDAETGETRWIMENSDIKVGSTLTIAPYV 164 Query: 248 DTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGSVND---FIVDGN--RIYLVDQN 302 V+V L G +TA D++SG++ W+ ++ D N + +N Sbjct: 165 IKDLVLVGSSGAELGVRGYVTAYDVKSGEMRWRAFATGPDEELLLAEDFNAPNPHYGQKN 224 Query: 303 DRVMALTID----GGVTLWT------QSDLLHRLLTSPVLYNGNLVVGD 341 + D GG T W + DL + +P +N + GD Sbjct: 225 LGLETWEGDAWKIGGGTNWGWYAYDPEVDLFYYGSGNPAPWNETMRPGD 273 Score = 29.4 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 3/56 (5%) Query: 265 GNLTALDLRSGQIMWKR-ELGSVND--FIVDGNRIYLVDQNDRVMALTIDGGVTLW 317 G + A D SG++ W++ E SV G + + + A D G LW Sbjct: 453 GQIKAYDAISGEMKWEKMERFSVWGGTMATAGGLTFYATLDGFIKARDSDTGDLLW 508 Score = 27.8 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 16/32 (50%) Query: 66 ALADNVVYAADRAGLVKALNADDGKEIWSVSL 97 A A + + A G +KA ++D G +W L Sbjct: 481 ATAGGLTFYATLDGFIKARDSDTGDLLWKFKL 512 >2D0V-A nrPDB Length = 597 Score = 48.6 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 37/178 (20%), Positives = 56/178 (31%), Gaps = 23/178 (12%) Query: 37 TVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRA-GLVKALNADD-GKEIWS 94 V+N AWS S G G P + +V+Y AL+ +D G +W Sbjct: 33 NVDNVKQLKHAWSFSTGELHG---HEGAPLVIGDVMYVHSSFPNKTFALDLNDPGHILWQ 89 Query: 95 VS-LAEKDGWFSKEPALLSGGVTVSGG------HVYIGSEKAQVYALNTSDGTVAWQT-- 145 S + L++ G+ G + + ALN G W+ Sbjct: 90 HSPKQDPAARSVACCDLVNRGLAYWPGDDKTPSLIIKTQLDGHLVALNAKTGEEFWKVEN 149 Query: 146 ---KVAGEALSRPVVSDGLVLIHTSN------GQLQALNEADGAVKWTVNLDMPSLSL 194 KV P V L ++ +S G + A N G W P + Sbjct: 150 GDIKVGQTLTQAPYVVHDLAIVGSSGAELGVRGHVTAYNVRTGEQAWRYYATGPDAEI 207 Score = 34.4 bits (77), Expect = 0.078, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 40/120 (33%), Gaps = 25/120 (20%) Query: 248 DTTPVVVNGVVFA-LAYNGNLTALDLRS-GQIMWKRE-----LGSVNDFIVDGNR----- 295 + P+V+ V++ ++ ALDL G I+W+ NR Sbjct: 55 EGAPLVIGDVMYVHSSFPNKTFALDLNDPGHILWQHSPKQDPAARSVACCDLVNRGLAYW 114 Query: 296 ---------IYLVDQNDRVMALTIDGGVTLW--TQSDLL--HRLLTSPVLYNGNLVVGDS 342 I + ++AL G W D+ L +P + + +VG S Sbjct: 115 PGDDKTPSLIIKTQLDGHLVALNAKTGEEFWKVENGDIKVGQTLTQAPYVVHDLAIVGSS 174 >1H4I-A nrPDB Length = 599 Score = 47.1 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 38/188 (20%), Positives = 53/188 (28%), Gaps = 23/188 (12%) Query: 28 DVVKMSPLPTVE--NQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALN 85 D S L + N AW+ S G + N + + + AL Sbjct: 22 DSNNFSDLKQINKGNVKQLRPAWTFSTG--LLNGHEGAPLVVDGKMYIHTSFPNNTFALG 79 Query: 86 ADD-GKEIWS-VSLAEKDGWFSKEPALLSGGVTVSGG------HVYIGSEKAQVYALNTS 137 DD G +W L++ G+ G + V ALN Sbjct: 80 LDDPGTILWQDKPKQNPAARAVACCDLVNRGLAYWPGDGKTPALILKTQLDGNVAALNAE 139 Query: 138 DGTVAWQT-----KVAGEALSRPVVSDGLVLIHTSN------GQLQALNEADGAVKWTVN 186 G W+ KV P V V+I +S G L A + G W Sbjct: 140 TGETVWKVENSDIKVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVKTGEQVWRAY 199 Query: 187 LDMPSLSL 194 P L Sbjct: 200 ATGPDKDL 207 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 32/79 (40%), Gaps = 9/79 (11%) Query: 79 GLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSD 138 G +KA NA G W + W G + +G V+ G+ + A ++ Sbjct: 453 GQIKAYNAITGDYKWEK-MERFAVWG--------GTMATAGDLVFYGTLDGYLKARDSDT 503 Query: 139 GTVAWQTKVAGEALSRPVV 157 G + W+ K+ A+ P+ Sbjct: 504 GDLLWKFKIPSGAIGYPMT 522 Score = 34.4 bits (77), Expect = 0.092, Method: Composition-based stats. Identities = 35/171 (20%), Positives = 60/171 (35%), Gaps = 40/171 (23%) Query: 220 LMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFA-LAYNGNLTALDLRS-GQI 277 ++Q + W G + P+VV+G ++ ++ N AL L G I Sbjct: 36 NVKQLRPAWTFSTGLLNGH---------EGAPLVVDGKMYIHTSFPNNTFALGLDDPGTI 86 Query: 278 MWKRE-----LGSVNDFIVDGNR--------------IYLVDQNDRVMALTIDGGVTLW- 317 +W+ + NR I + V AL + G T+W Sbjct: 87 LWQDKPKQNPAARAVACCDLVNRGLAYWPGDGKTPALILKTQLDGNVAALNAETGETVWK 146 Query: 318 -TQSDLL--HRLLTSPVLYNGNLVVGDS------EGYLHWINVEDGRFVAQ 359 SD+ L +P + +++G S GYL +V+ G V + Sbjct: 147 VENSDIKVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVKTGEQVWR 197 Score = 32.4 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 43/212 (20%), Positives = 78/212 (36%), Gaps = 39/212 (18%) Query: 73 YAADRAGLVKALNADDGKEI---WSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKA 129 Y ++ +K +N + K++ W+ S P ++ G + + S Sbjct: 21 YDSNNFSDLKQINKGNVKQLRPAWTFSTGL-LNGHEGAPLVVDGKMYIH------TSFPN 73 Query: 130 QVYALNTSD-GTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLD 188 +AL D GT+ WQ K +R V LV G W + Sbjct: 74 NTFALGLDDPGTILWQDKPKQNPAARAVACCDLV--------------NRGLAYWPGDGK 119 Query: 189 MPSLSLRGESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVD 248 P+L L+ + +G V+A+ E G+ +W+ S + + V Sbjct: 120 TPALILKTQ--------------LDGNVAALNAETGETVWKVENSDIKVGSTLTIAPYVV 165 Query: 249 TTPVVVNGVVFALAYNGNLTALDLRSGQIMWK 280 V++ L G LTA D+++G+ +W+ Sbjct: 166 KDKVIIGSSGAELGVRGYLTAYDVKTGEQVWR 197 >4TQO-B nrPDB Length = 573 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 34/175 (19%), Positives = 58/175 (33%), Gaps = 23/175 (13%) Query: 40 NQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRA-GLVKALN-ADDGKEIWSVSL 97 N AW+ S G+ G P + D ++Y V A++ D K +W Sbjct: 36 NVKNLKVAWTLSTGTLHG---HEGAPLVVDGIMYIHTPFPNNVYAVDLNDTRKMLWQYKP 92 Query: 98 AE-KDGWFSKEPALLSGGVTV--SGGH----VYIGSEKAQVYALNTSDGTVAWQTK---- 146 + +++ G+ +G H +++ + ALN G W+ + Sbjct: 93 KQNPAARAVACCDVVNRGLAYVPAGEHGPAKIFLNQLDGHIVALNAKTGEEIWKMENSDI 152 Query: 147 -VAGEALSRPVVSDGLVLI------HTSNGQLQALNEADGAVKWTVNLDMPSLSL 194 + P V VL+ G + A N DG +W P L Sbjct: 153 AMGSTLTGAPFVVKDKVLVGSAGAELGVRGYVTAYNIKDGKQEWRAYATGPDEDL 207 Score = 42.5 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 58/139 (41%), Gaps = 31/139 (22%) Query: 248 DTTPVVVNGVVFA-LAYNGNLTALDLRSGQ-IMWK-------------------RELGSV 286 + P+VV+G+++ + N+ A+DL + ++W+ R L V Sbjct: 55 EGAPLVVDGIMYIHTPFPNNVYAVDLNDTRKMLWQYKPKQNPAARAVACCDVVNRGLAYV 114 Query: 287 NDFIVDGNRIYLVDQNDRVMALTIDGGVTLW--TQSDLL--HRLLTSPVLYNGNLVVGDS 342 +I+L + ++AL G +W SD+ L +P + ++VG + Sbjct: 115 PAGEHGPAKIFLNQLDGHIVALNAKTGEEIWKMENSDIAMGSTLTGAPFVVKDKVLVGSA 174 Query: 343 ------EGYLHWINVEDGR 355 GY+ N++DG+ Sbjct: 175 GAELGVRGYVTAYNIKDGK 193 Score = 42.5 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 9/79 (11%) Query: 79 GLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSD 138 G VKA+NA GK W V W G + +G V+ G+ + A +T Sbjct: 446 GQVKAMNAVTGKMEWEVPEKFAV-WG--------GTLATAGDLVFYGTLDGFIKARDTRT 496 Query: 139 GTVAWQTKVAGEALSRPVV 157 G + WQ ++ + P+ Sbjct: 497 GELKWQFQLPSGVIGHPIT 515 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 41/203 (20%), Positives = 72/203 (35%), Gaps = 38/203 (18%) Query: 73 YAADRAGLVKALNA---DDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKA 129 Y+A + +N+ + K W++S P ++ G + + Sbjct: 21 YSATHFSRLTEINSHNVKNLKVAWTLSTG-TLHGHEGAPLVVDGIMYIH------TPFPN 73 Query: 130 QVYALNTS-DGTVAWQTKVAGEALSRPVVSDGLV-----------------LIHTSNGQL 171 VYA++ + + WQ K +R V +V ++ +G + Sbjct: 74 NVYAVDLNDTRKMLWQYKPKQNPAARAVACCDVVNRGLAYVPAGEHGPAKIFLNQLDGHI 133 Query: 172 QALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVG------GDNGRVSAVLMEQGQ 225 ALN G W + ++ AP +VG G G V+A ++ G+ Sbjct: 134 VALNAKTGEEIWKMENSDIAMGSTLTGAPFVVKDKVLVGSAGAELGVRGYVTAYNIKDGK 193 Query: 226 MIWQQRISQATGSTEIDRLSDVD 248 W+ + ATG E D L D D Sbjct: 194 QEWR---AYATGPDE-DLLLDKD 212 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 32/72 (44%), Gaps = 10/72 (13%) Query: 214 GRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLR 273 G+V A+ G+M W+ ++ + T +VF +G + A D R Sbjct: 446 GQVKAMNAVTGKMEWEVP----------EKFAVWGGTLATAGDLVFYGTLDGFIKARDTR 495 Query: 274 SGQIMWKRELGS 285 +G++ W+ +L S Sbjct: 496 TGELKWQFQLPS 507 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 26/61 (42%), Gaps = 4/61 (6%) Query: 169 GQLQALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIW 228 GQ++A+N G ++W ++P TA G +G + A G++ W Sbjct: 446 GQVKAMNAVTGKMEW----EVPEKFAVWGGTLATAGDLVFYGTLDGFIKARDTRTGELKW 501 Query: 229 Q 229 Q Sbjct: 502 Q 502 >5XM3-A nrPDB Length = 627 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 53/176 (30%), Gaps = 23/176 (13%) Query: 39 ENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADD-GKEIWS-VS 96 +N +WS S G + N + + + A++ D+ G W Sbjct: 66 DNVKKLRPSWSFSTG--VLNGHEGAPLVVNGTMYIHTPFPNNTFAIDLDEPGVIKWEHKP 123 Query: 97 LAEKDGWFSKEPALLSGGVTVSGG------HVYIGSEKAQVYALNTSDGTVAWQTK---- 146 + +++ G+ G + V ALN G W+ + Sbjct: 124 KQDPAARAVACCDVVNRGLAYWPGDDKAPAMIVKSLLDGHVVALNAETGEEYWKVENGDI 183 Query: 147 -VAGEALSRPVVSDGLVLIHTSNGQLQAL-------NEADGAVKWTVNLDMPSLSL 194 V + P V+ LV I S+G + + G + W P + Sbjct: 184 SVGQTETAAPFVAKDLV-IQGSSGAELGVRGYVTAYDIHTGEMVWRWYATGPDADV 238 Score = 42.5 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 32/80 (40%), Gaps = 9/80 (11%) Query: 78 AGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTS 137 +G VKA NA G+ W + + W G GG V+ G+ + A + Sbjct: 483 SGQVKAYNAITGEFAWEK-MEKFSVWG--------GTTATEGGLVFYGTLDGFIKARDAD 533 Query: 138 DGTVAWQTKVAGEALSRPVV 157 G + W+ K+ + P+ Sbjct: 534 TGKLLWKFKLPSGVIGHPMT 553 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 38/198 (19%), Positives = 71/198 (35%), Gaps = 34/198 (17%) Query: 73 YAADRAGLVKALNADDGKEI---WSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKA 129 ++ K +N D+ K++ WS S P +++G + + Sbjct: 52 FSGTHYSTAKQINKDNVKKLRPSWSFSTGV-LNGHEGAPLVVNGTMYIH------TPFPN 104 Query: 130 QVYALN-TSDGTVAWQTKVAGEALSRPVVSDGLV---------------LIHTS--NGQL 171 +A++ G + W+ K + +R V +V +I S +G + Sbjct: 105 NTFAIDLDEPGVIKWEHKPKQDPAARAVACCDVVNRGLAYWPGDDKAPAMIVKSLLDGHV 164 Query: 172 QALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVG------GDNGRVSAVLMEQGQ 225 ALN G W V S+ +AP A + G G G V+A + G+ Sbjct: 165 VALNAETGEEYWKVENGDISVGQTETAAPFVAKDLVIQGSSGAELGVRGYVTAYDIHTGE 224 Query: 226 MIWQQRISQATGSTEIDR 243 M+W+ + +D+ Sbjct: 225 MVWRWYATGPDADVGLDK 242 Score = 33.2 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 10/76 (13%) Query: 210 GGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTA 269 G +G+V A G+ W++ +++ S T G+VF +G + A Sbjct: 480 GIGSGQVKAYNAITGEFAWEK----------MEKFSVWGGTTATEGGLVFYGTLDGFIKA 529 Query: 270 LDLRSGQIMWKRELGS 285 D +G+++WK +L S Sbjct: 530 RDADTGKLLWKFKLPS 545 Score = 32.8 bits (73), Expect = 0.27, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 53/148 (35%), Gaps = 15/148 (10%) Query: 147 VAGEALSRPVVSDGLVLIHTSNGQLQALNEAD-GAVKWTVN------------LDMPSLS 193 + G + VV+ + + A++ + G +KW D+ + Sbjct: 82 LNGHEGAPLVVNGTMYIHTPFPNNTFAIDLDEPGVIKWEHKPKQDPAARAVACCDVVNRG 141 Query: 194 LRGESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRIS-QATGSTEIDRLSDVDTTPV 252 L A V +G V A+ E G+ W+ + G TE V V Sbjct: 142 LAYWPGDDKAPAMIVKSLLDGHVVALNAETGEEYWKVENGDISVGQTET-AAPFVAKDLV 200 Query: 253 VVNGVVFALAYNGNLTALDLRSGQIMWK 280 + L G +TA D+ +G+++W+ Sbjct: 201 IQGSSGAELGVRGYVTAYDIHTGEMVWR 228 >6DAM-A nrPDB Length = 617 Score = 42.1 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 38/176 (21%), Positives = 65/176 (36%), Gaps = 24/176 (13%) Query: 73 YAADRAGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSE-KAQV 131 Y R +K +N + K +L + + GG V +YI + V Sbjct: 47 YHGTRYSELKQINTSNVK-----NLQPAWTFSTGVLRGHEGGPLVVNDVMYIHTPFPNTV 101 Query: 132 YALNTSDGTVAWQ-TKVAGEALSRPVV-----------SDGLVLIHTSNGQLQALNEADG 179 YA++ V W+ T ++ PV+ DG + + S+ L AL+ G Sbjct: 102 YAIDQKTQAVIWEYTPQQDADVTIPVMCCDTVNRGLAYGDGKIFLQQSDTVLTALDAKTG 161 Query: 180 AVKWTVNLDMPSLSLRGESAPTTAFGAAVVG------GDNGRVSAVLMEQGQMIWQ 229 W+V P L + AP + G G G ++A + G++ W+ Sbjct: 162 KRVWSVQNGDPKLGMTNTQAPLVVKDKVITGISGGEFGVRGFLAAYNIRTGELDWK 217 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 27/179 (15%), Positives = 68/179 (37%), Gaps = 18/179 (10%) Query: 155 PVVSDGLVLIHTS-NGQLQALNEADGAVKWTV------NLDMPSLSLRGESAPTT-AFGA 206 P+V + ++ IHT + A+++ AV W ++ +P + + G Sbjct: 84 PLVVNDVMYIHTPFPNTVYAIDQKTQAVIWEYTPQQDADVTIPVMCCDTVNRGLAYGDGK 143 Query: 207 AVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALA---- 262 + + ++A+ + G+ +W + +++ VV + V+ ++ Sbjct: 144 IFLQQSDTVLTALDAKTGKRVWSVQNGDPKLG-----MTNTQAPLVVKDKVITGISGGEF 198 Query: 263 -YNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQS 320 G L A ++R+G++ WK + + ++ +V + D + W Sbjct: 199 GVRGFLAAYNIRTGELDWKGYSMGPDADTLINPTKTTTWKDGKVQPVGKDSSTSTWEGD 257 Score = 35.9 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 32/80 (40%), Gaps = 1/80 (1%) Query: 66 ALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDGWFSKEPA-LLSGGVTVSGGHVYI 124 A D ++ ++ AL+A GK +WSV + + A L+ ++G Sbjct: 138 AYGDGKIFLQQSDTVLTALDAKTGKRVWSVQNGDPKLGMTNTQAPLVVKDKVITGISGGE 197 Query: 125 GSEKAQVYALNTSDGTVAWQ 144 + + A N G + W+ Sbjct: 198 FGVRGFLAAYNIRTGELDWK 217 Score = 32.8 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 29/71 (40%), Gaps = 9/71 (12%) Query: 79 GLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSD 138 G A +A GK IWS + SG + +GG V+ G+ + + A++ Sbjct: 483 GQFTAWDATTGKIIWSNKEQFS---------VWSGSLATAGGVVFYGTLEGYLKAVDAKT 533 Query: 139 GTVAWQTKVAG 149 G ++ K Sbjct: 534 GKELYRFKTPS 544 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 27/75 (36%), Gaps = 6/75 (8%) Query: 119 GGHVYIGSEKA-----QVYALNTSDGTVAWQTKVAGEALSRPV-VSDGLVLIHTSNGQLQ 172 G V G E Q A + + G + W K S + + G+V T G L+ Sbjct: 468 GKDVITGKEDGSNNLGQFTAWDATTGKIIWSNKEQFSVWSGSLATAGGVVFYGTLEGYLK 527 Query: 173 ALNEADGAVKWTVNL 187 A++ G + Sbjct: 528 AVDAKTGKELYRFKT 542 Score = 29.4 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 35/95 (36%), Gaps = 13/95 (13%) Query: 265 GNLTALDLRSGQIMW--KRELGSVND-FIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSD 321 G TA D +G+I+W K + + G ++ + A+ G L+ Sbjct: 483 GQFTAWDATTGKIIWSNKEQFSVWSGSLATAGGVVFYGTLEGYLKAVDAKTGKELYR--- 539 Query: 322 LLHRLLTSPVLYNGNLVVGDSEG--YLHWINVEDG 354 +P GN+ + EG Y+ ++ G Sbjct: 540 -----FKTPSGIIGNVNTWEYEGKQYVGVLSGVGG 569 >2OAS-A nrPDB Length = 436 Score = 30.9 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 47/105 (44%), Gaps = 5/105 (4%) Query: 272 LRSGQIMWKRELGSVNDFIVDGNRIYLVDQND-RVMALTIDGGVTLWTQS---DLLHRLL 327 +RSG+ +W +G+ ++D + + ++ ++ L +G +L S L HR Sbjct: 16 IRSGETLWTHSMGATPKVLLDALAKHALTLDNITLLQLHTEGAESLSHPSLLGHLRHRCF 75 Query: 328 TSPVLYNGNLVVGDSEGYLHWINVEDGRF-VAQQKVDSSGFQTEP 371 V L GD++ +++ F +QK+D++ Q P Sbjct: 76 FGGVPTRPLLQSGDADYVPIFLSEVPKLFRSGEQKIDTAIIQVSP 120 >5JKJ-A nrPDB Length = 370 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 50/149 (33%), Gaps = 9/149 (6%) Query: 154 RPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVGGDN 213 V++ G I+ G+ L+ ++ VN+ L G S AV+G Sbjct: 98 PHVITTGPTSINPDTGKPYGLDFPVVTIRDFVNVQKALLESLGISKLY-----AVIGPSM 152 Query: 214 GRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVD----TTPVVVNGVVFALAYNGNLTA 269 G + A+ W +R+ G+ + D + TP+ ++ AY+ Sbjct: 153 GSMQAIDWASAYPGWVERMISVIGAGQSDAWTTAALEHWATPITLDKNWNNGAYSKEQAP 212 Query: 270 LDLRSGQIMWKRELGSVNDFIVDGNRIYL 298 L+ + +M + F Sbjct: 213 LNGLAASLMLITQNALTPSFFNQTGNTLG 241 >3NDO-A nrPDB Length = 231 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 5/82 (6%) Query: 166 TSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVGGDNGRVSAVLMEQGQ 225 T + ++EA + V + P +S+ AP+ AAV G +G+ G Sbjct: 27 TPSDVTALVDEAADLGVFAVCVSPPLVSVAAGVAPSGLAIAAVAGFPSGKHVP-----GI 81 Query: 226 MIWQQRISQATGSTEIDRLSDV 247 + ++ A G+TEID + DV Sbjct: 82 KATEAELAVAAGATEIDMVIDV 103 >3G9W-A nrPDB Length = 223 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 30/61 (49%) Query: 1 MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFY 60 M+ + L+P LL +T S + ++V++ PL TV+ +++ G ++Y Sbjct: 137 MKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYY 196 Query: 61 S 61 S Sbjct: 197 S 197 >1Q90-A nrPDB Length = 292 Score = 27.8 bits (60), Expect = 9.0, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 27/67 (40%), Gaps = 1/67 (1%) Query: 25 SEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKAL 84 SE V +SP P +N+ + G G ++N +Y A AG + A+ Sbjct: 124 SEMVVPILSPDP-AKNKNVSYLKYPIYFGGNRGRGQVYPDGKKSNNTIYNASAAGKIVAI 182 Query: 85 NADDGKE 91 A K+ Sbjct: 183 TALSEKK 189 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.125 0.322 Lambda K H 0.267 0.0386 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,885,427 Number of Sequences: 36641 Number of extensions: 527144 Number of successful extensions: 1878 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 1496 Number of HSP's gapped (non-prelim): 195 length of query: 392 length of database: 10,336,785 effective HSP length: 99 effective length of query: 293 effective length of database: 6,709,326 effective search space: 1965832518 effective search space used: 1965832518 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.8 bits)