BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P63098 (170 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4ORC-B nrPDB 343 3e-95 4IL1-A nrPDB 342 4e-95 5B8I-B nrPDB 207 2e-54 2E30-A nrPDB 132 1e-31 2BEC-A nrPDB 112 7e-26 6O20-F nrPDB 86 9e-18 5A2H-A nrPDB 86 1e-17 3WFN-B nrPDB 86 1e-17 4E53-A nrPDB 85 1e-17 2F2P-A nrPDB 85 1e-17 2N6A-A nrPDB 85 1e-17 3EK4-A nrPDB 84 3e-17 6HCS-A nrPDB 83 5e-17 5I0I-E nrPDB 83 6e-17 4OY4-A nrPDB 81 2e-16 2L1W-A nrPDB 80 3e-16 3U0K-A nrPDB 80 4e-16 1GGZ-A nrPDB 79 1e-15 5T7C-A nrPDB 78 2e-15 2ZFD-A nrPDB 78 2e-15 1UHN-A nrPDB 78 2e-15 1BJF-A nrPDB 77 5e-15 1CLM-A nrPDB 76 8e-15 4I2Y-A nrPDB 75 1e-14 2LM5-A nrPDB 74 4e-14 1DGU-A nrPDB 74 4e-14 1V1G-A nrPDB 73 7e-14 2L2E-A nrPDB 73 8e-14 5UKG-A nrPDB 72 9e-14 6EPA-A nrPDB 72 1e-13 2LCP-A nrPDB 71 2e-13 3DD4-A nrPDB 70 4e-13 4DS7-A nrPDB 70 5e-13 2JU0-A nrPDB 70 5e-13 5M6C-E nrPDB 69 1e-12 2TN4-A nrPDB 69 1e-12 2LMV-A nrPDB 68 2e-12 5ZOR-A nrPDB 68 2e-12 1LKJ-A nrPDB 67 3e-12 2LHI-A nrPDB 67 3e-12 3KF9-A nrPDB 66 6e-12 2R2I-A nrPDB 66 6e-12 1TOP-A nrPDB 65 2e-11 2JNF-A nrPDB 64 5e-11 2GGM-A nrPDB 64 5e-11 2OBH-A nrPDB 63 7e-11 1JBA-A nrPDB 63 8e-11 2NA0-A nrPDB 62 8e-11 2LAP-A nrPDB 62 9e-11 1S6C-A nrPDB 62 9e-11 5YPX-A nrPDB 62 9e-11 1S1E-A nrPDB 62 1e-10 3NCG-A nrPDB 62 1e-10 2LHH-A nrPDB 61 2e-10 5D43-A nrPDB 61 2e-10 2AAO-A nrPDB 61 3e-10 2JUL-A nrPDB 60 5e-10 1DTL-A nrPDB 59 9e-10 2JNX-A nrPDB 59 1e-09 1S6I-A nrPDB 58 2e-09 3O4Y-A nrPDB 58 2e-09 4JWQ-A nrPDB 58 2e-09 2I94-A nrPDB 57 4e-09 2GGZ-A nrPDB 57 4e-09 2RO9-A nrPDB 56 8e-09 3QRX-A nrPDB 55 1e-08 1FW4-A nrPDB 55 1e-08 2HF5-A nrPDB 55 2e-08 3K21-A nrPDB 55 2e-08 2KN2-A nrPDB 54 2e-08 2ROB-A nrPDB 54 2e-08 4MVF-A nrPDB 54 4e-08 2LC5-A nrPDB 54 4e-08 2KZ2-A nrPDB 53 5e-08 2M29-A nrPDB 53 6e-08 2D8N-A nrPDB 53 7e-08 3PM8-A nrPDB 52 1e-07 1JFJ-A nrPDB 52 2e-07 1M39-A nrPDB 50 4e-07 2K2I-A nrPDB 49 1e-06 2K2A-A nrPDB 48 2e-06 3AAJ-A nrPDB 48 2e-06 4YZB-A nrPDB 48 2e-06 2M5E-A nrPDB 48 2e-06 2K7C-A nrPDB 47 4e-06 3MSE-B nrPDB 46 6e-06 2BL0-B nrPDB 46 6e-06 2LV7-A nrPDB 46 7e-06 3Q5I-A nrPDB 46 8e-06 2E6W-A nrPDB 46 9e-06 3LIJ-A nrPDB 46 9e-06 3L19-A nrPDB 46 1e-05 5JOL-A nrPDB 45 1e-05 5JN2-A nrPDB 45 1e-05 4RGJ-A nrPDB 45 1e-05 3IFK-A nrPDB 45 2e-05 5JOJ-A nrPDB 45 2e-05 1JC2-A nrPDB 45 2e-05 5ZGM-A nrPDB 44 3e-05 3FWC-A nrPDB 43 6e-05 2B1U-A nrPDB 43 7e-05 5H7D-E nrPDB 43 7e-05 3KHE-A nrPDB 42 1e-04 3HZT-A nrPDB 42 1e-04 4WPX-A nrPDB 42 1e-04 1RTP-1 nrPDB 42 1e-04 2L50-A nrPDB 42 2e-04 1G33-A nrPDB 42 2e-04 4N5X-A nrPDB 42 2e-04 1OZS-A nrPDB 41 2e-04 2I08-A nrPDB 41 2e-04 5PAL-A nrPDB 41 2e-04 5COC-A nrPDB 41 2e-04 4Q57-A nrPDB 41 2e-04 4ZCV-A nrPDB 40 4e-04 3SIA-A nrPDB 40 4e-04 5E37-A nrPDB 40 5e-04 1TNP-A nrPDB 40 6e-04 1TRF-A nrPDB 40 6e-04 2PMY-A nrPDB 40 6e-04 2RO8-A nrPDB 40 7e-04 1GGW-A nrPDB 40 7e-04 6IIE-A nrPDB 39 0.001 2N7L-C nrPDB 39 0.001 5VLN-A nrPDB 39 0.001 2M97-A nrPDB 39 0.001 5XND-A nrPDB 38 0.002 3TZ1-A nrPDB 38 0.002 2BL0-C nrPDB 38 0.002 3E3R-A nrPDB 38 0.002 4GJF-A nrPDB 38 0.003 5VE9-A nrPDB 37 0.004 3PAT-A nrPDB 37 0.004 5MWC-D nrPDB 37 0.004 2LVK-A nrPDB 37 0.004 2AMI-A nrPDB 37 0.005 1RK9-A nrPDB 37 0.006 5OTJ-D nrPDB 37 0.006 5CPV-A nrPDB 37 0.006 5XOP-A nrPDB 37 0.006 1OQP-A nrPDB 36 0.008 2KSZ-A nrPDB 36 0.009 2N8Y-A nrPDB 35 0.012 1W7I-B nrPDB 35 0.012 5CSF-A nrPDB 35 0.014 1H4B-A nrPDB 35 0.015 2M7M-A nrPDB 35 0.016 1Y1X-A nrPDB 35 0.017 2K7B-A nrPDB 35 0.018 1S6J-A nrPDB 35 0.019 1YX7-A nrPDB 35 0.022 1F55-A nrPDB 34 0.024 4PAL-A nrPDB 34 0.029 1C7W-A nrPDB 34 0.032 2OPO-A nrPDB 34 0.035 2Q4U-A nrPDB 33 0.050 2WCE-A nrPDB 33 0.055 1SR6-C nrPDB 33 0.062 2KQY-A nrPDB 33 0.065 2M8U-A nrPDB 33 0.083 2KGR-A nrPDB 32 0.094 3DF0-A nrPDB 32 0.10 1ZMZ-A nrPDB 32 0.11 1KFU-L nrPDB 32 0.11 3I5I-C nrPDB 32 0.11 4D1E-A nrPDB 32 0.11 2NLN-A nrPDB 32 0.12 2KYF-A nrPDB 32 0.14 2LUC-A nrPDB 32 0.14 1TTX-A nrPDB 32 0.14 1SJJ-A nrPDB 32 0.14 1A75-A nrPDB 32 0.15 5B7X-A nrPDB 32 0.16 4HRG-A nrPDB 32 0.16 4FTG-A nrPDB 32 0.16 1QX2-A nrPDB 32 0.17 5HYD-A nrPDB 32 0.20 4OCI-A nrPDB 31 0.20 1BU3-A nrPDB 31 0.23 5VP3-A nrPDB 31 0.24 6AGI-A nrPDB 31 0.25 1QXP-A nrPDB 31 0.26 1TIZ-A nrPDB 31 0.28 2G9B-A nrPDB 31 0.30 1NSH-A nrPDB 31 0.34 1ZFS-A nrPDB 30 0.45 1N2D-A nrPDB 30 0.47 1QLS-A nrPDB 30 0.48 2FCE-A nrPDB 30 0.48 5TBY-E nrPDB 30 0.54 2L0P-A nrPDB 30 0.58 2I18-A nrPDB 30 0.62 3AKA-A nrPDB 30 0.68 2Y5I-A nrPDB 29 0.79 1NYA-A nrPDB 29 0.79 4NSC-A nrPDB 29 0.84 4OKH-A nrPDB 29 0.85 1CB1-A nrPDB 29 0.94 6MI5-X nrPDB 29 0.99 2LVV-A nrPDB 29 1.1 4L9M-A nrPDB 29 1.2 3BOW-B nrPDB 28 1.3 1BOD-A nrPDB 28 1.3 6EAZ-A nrPDB 28 1.4 1NP8-A nrPDB 28 1.5 5I2L-A nrPDB 28 1.5 4NQG-A nrPDB 28 1.6 2HPS-A nrPDB 28 1.8 4MN0-A nrPDB 28 1.9 1KQV-A nrPDB 28 2.1 1KFX-S nrPDB 28 2.3 2MA2-A nrPDB 27 3.4 2MBX-A nrPDB 27 3.7 1S36-A nrPDB 27 4.1 1B7T-Y nrPDB 27 4.2 5H53-B nrPDB 27 4.7 1DFK-Y nrPDB 27 4.7 5ZH6-A nrPDB 27 5.0 3DTP-E nrPDB 27 5.1 1IJ5-A nrPDB 27 5.4 1I84-U nrPDB 27 5.5 2JOJ-A nrPDB 27 5.6 1O1A-B nrPDB 27 5.6 6DS2-B nrPDB 27 5.7 2JTT-A nrPDB 27 6.2 3KPX-A nrPDB 27 6.4 2MJW-B nrPDB 27 6.4 5Z1Q-A nrPDB 26 6.7 3ERV-A nrPDB 26 7.5 2KY4-A nrPDB 26 8.8 >4ORC-B nrPDB Length = 170 Score = 343 bits (879), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 170/170 (100%), Positives = 170/170 (100%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID 60 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID Sbjct: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID 60 Query: 61 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV 120 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV Sbjct: 61 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV 120 Query: 121 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV Sbjct: 121 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 >4IL1-A nrPDB Length = 823 Score = 342 bits (877), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 168/168 (100%), Positives = 168/168 (100%) Query: 3 NEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF 62 NEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF Sbjct: 160 NEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF 219 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN Sbjct: 220 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 279 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV Sbjct: 280 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 327 Score = 83.6 bits (205), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 51/147 (34%), Positives = 82/147 (55%), Gaps = 9/147 (6%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ NL + Sbjct: 61 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGE 115 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEF 153 + VD+ I AD DGDG++++EEF Sbjct: 116 KLTDEEVDEMIREADIDGDGQVNYEEF 142 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 41/165 (24%), Positives = 69/165 (41%), Gaps = 38/165 (23%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E +L E + V +I D DG+G+V+ Sbjct: 79 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 138 Query: 72 FKEFI-----------------------EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYIS 108 ++EF+ E S F D+ ++L F+ D+D G +S Sbjct: 139 YEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFD--ADEIKRLGKRFKKLDLDNSGSLS 196 Query: 109 NGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 E +L + Q +V + I D DG+G + F+EF Sbjct: 197 VEEFM---------SLPELQQNPLVQRVIDIFDTDGNGEVDFKEF 232 >5B8I-B nrPDB Length = 171 Score = 207 bits (527), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 100/157 (63%), Positives = 126/157 (80%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDF 72 S+FD +E+ RL KRF KLD D SG++ +EF+SLP++ NPL R+I IFD DG G+VDF Sbjct: 13 SNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLSTRMIAIFDEDGGGDVDF 72 Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQI 132 +EF+ G+S FS KG+KE+KLRFAF++YD+D+DG+ISNGELF VLKMMVG+NLKD QLQQI Sbjct: 73 QEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNLKDMQLQQI 132 Query: 133 VDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVD 169 VDKTI+ AD DGDGRISFEEF +V D+ M +D Sbjct: 133 VDKTIMEADLDGDGRISFEEFTRMVENTDVSMSMTLD 169 >2E30-A nrPDB Length = 195 Score = 132 bits (331), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 73/169 (43%), Positives = 99/169 (58%), Gaps = 15/169 (8%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 F +I RL RF LD +G+LS E+F +PEL NPL R+I+ F +G +V+F+ Sbjct: 23 FSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRG 82 Query: 75 FIEGVSQFSVKGDKEQ---------------KLRFAFRIYDMDKDGYISNGELFQVLKMM 119 F+ ++ F D E+ KL FAFR+YD+DKD IS EL QVL+MM Sbjct: 83 FMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEKISRDELLQVLRMM 142 Query: 120 VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVV 168 VG N+ D QL I D+TI AD+DGD ISF EF V+ +D+ +KM + Sbjct: 143 VGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSI 191 >2BEC-A nrPDB Length = 202 Score = 112 bits (281), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 61/172 (35%), Positives = 94/172 (54%), Gaps = 16/172 (9%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 F + RL RF+ LD + G LS + + L NPL R+I+ F DG+ VDF Sbjct: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPG 82 Query: 75 FIEGVSQFSVKGD----------------KEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 F+ ++ F D + KL +AF++YD+D+DG IS E+ QVL++ Sbjct: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 Query: 119 MVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 MVG + + QL+ I D+T+ AD+DGDG +SF EF + +D+ +KM + + Sbjct: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 >6O20-F nrPDB Length = 169 Score = 85.9 bits (211), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 51/151 (33%), Positives = 84/151 (55%), Gaps = 9/151 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 21 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 80 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ NL + Sbjct: 81 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGE 135 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + VD+ I AD DGDG++++EEF ++ Sbjct: 136 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 166 >5A2H-A nrPDB Length = 149 Score = 85.5 bits (210), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 53/151 (35%), Positives = 84/151 (55%), Gaps = 9/151 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M D+I + F D D G ++ +E + + L QNP +Q +I+ D DG Sbjct: 1 MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E++L+ AFR++D D++G+IS EL V+ NL + Sbjct: 61 NGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVM-----TNLGE 115 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + VD+ I AD DGDG+I++EEF V+ Sbjct: 116 KLTDEEVDEMIREADVDGDGQINYEEFVKVM 146 >3WFN-B nrPDB Length = 182 Score = 85.5 bits (210), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 51/151 (33%), Positives = 84/151 (55%), Gaps = 9/151 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 7 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 66 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ NL + Sbjct: 67 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGE 121 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + VD+ I AD DGDG++++EEF ++ Sbjct: 122 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 152 Score = 30.0 bits (66), Expect = 0.48, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 51/99 (51%), Gaps = 8/99 (8%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E +L E + V +I D DG+G+V+ Sbjct: 85 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 144 Query: 72 FKEFIEGVSQFSVKGDKEQK---LRFAFRIYDMDKDGYI 107 ++EF++ ++ G +E L+ A+R + + + G+I Sbjct: 145 YEEFVQMMTAKGGGGGEEVSAVVLQRAYRGH-LARRGFI 182 >4E53-A nrPDB Length = 185 Score = 85.1 bits (209), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 51/151 (33%), Positives = 84/151 (55%), Gaps = 9/151 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 8 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 67 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ NL + Sbjct: 68 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGE 122 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + VD+ I AD DGDG++++EEF ++ Sbjct: 123 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 29.6 bits (65), Expect = 0.76, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 4/86 (4%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E +L E + V +I D DG+G+V+ Sbjct: 86 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 145 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFR 97 ++EF++ ++ G K++ +FR Sbjct: 146 YEEFVQMMTAKGGGGGAATKIQASFR 171 >2F2P-A nrPDB Length = 179 Score = 85.1 bits (209), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 51/151 (33%), Positives = 84/151 (55%), Gaps = 9/151 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ NL + Sbjct: 61 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGE 115 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + VD+ I AD DGDG++++EEF ++ Sbjct: 116 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 >2N6A-A nrPDB Length = 173 Score = 85.1 bits (209), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 51/146 (34%), Positives = 84/146 (57%), Gaps = 9/146 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I + F D D G+++ +E + + L QNP +Q +I+ D DGNG +DF Sbjct: 9 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 68 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 EF+ +++ D E+++R AFR++D D +GYIS EL V+ NL + + V Sbjct: 69 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEEV 123 Query: 134 DKTIINADKDGDGRISFEEFCAVVGG 159 D+ I AD DGDG++++EEF ++ G Sbjct: 124 DEMIREADIDGDGQVNYEEFVQMMTG 149 >3EK4-A nrPDB Length = 451 Score = 84.0 bits (206), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 54/162 (33%), Positives = 89/162 (54%), Gaps = 11/162 (6%) Query: 2 GNEASYPLEMCS--HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---V 55 GN + LE + ++I + F D D G+++ +E + + L QNP + Sbjct: 292 GNILGHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAEL 351 Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 Q +I+ D DGNG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V Sbjct: 352 QDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 411 Query: 116 LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + NL + + VD+ I AD DGDG++++EEF ++ Sbjct: 412 M-----TNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 448 >6HCS-A nrPDB Length = 167 Score = 83.2 bits (204), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 50/151 (33%), Positives = 83/151 (54%), Gaps = 9/151 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL + NL + Sbjct: 61 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFM-----TNLGE 115 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + VD+ I AD DGDG++++EEF ++ Sbjct: 116 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 >5I0I-E nrPDB Length = 145 Score = 82.8 bits (203), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 50/144 (34%), Positives = 83/144 (57%), Gaps = 9/144 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I + F D D G+++ +E + + L QNP +Q +I+ D DGNG +DF Sbjct: 6 EQIAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 65 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 EF+ +++ D E+++R AFR++D D +GYIS EL V+ NL + + V Sbjct: 66 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEEV 120 Query: 134 DKTIINADKDGDGRISFEEFCAVV 157 D+ I AD DGDG++++EEF ++ Sbjct: 121 DEMIREADIDGDGQVNYEEFVQMM 144 Score = 29.3 bits (64), Expect = 0.78, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 4/66 (6%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E +L E + V +I D DG+G+V+ Sbjct: 77 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 136 Query: 72 FKEFIE 77 ++EF++ Sbjct: 137 YEEFVQ 142 >4OY4-A nrPDB Length = 415 Score = 81.3 bits (199), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 49/144 (34%), Positives = 83/144 (57%), Gaps = 9/144 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I + F D D G+++ +E + + L QNP +Q +I+ D DG+G +DF Sbjct: 15 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFP 74 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 EF+ +++ D E+++R AFR++D D +GYIS EL V+ NL + + V Sbjct: 75 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEEV 129 Query: 134 DKTIINADKDGDGRISFEEFCAVV 157 D+ I AD DGDG++++EEF ++ Sbjct: 130 DEMIREADIDGDGQVNYEEFVQMM 153 >2L1W-A nrPDB Length = 149 Score = 80.5 bits (197), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 48/135 (35%), Positives = 83/135 (61%), Gaps = 9/135 (6%) Query: 27 FKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVSQF 82 F D D G ++VEE + + L QNP +Q +I D DGNG ++F EF+ +++ Sbjct: 16 FGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLMAKK 75 Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 D E++L+ AF+++D D++GYIS EL V+ + +G L D +++Q++ + AD Sbjct: 76 VKDTDAEEELKEAFKVFDKDQNGYISASELRHVM-INLGEKLTDEEVEQMIKE----ADL 130 Query: 143 DGDGRISFEEFCAVV 157 DGDG++++EEF ++ Sbjct: 131 DGDGQVNYEEFVKMM 145 Score = 35.4 bits (80), Expect = 0.014, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF ++D D DG I+ EL V++ + N + +LQ ++ + D DG+G I F+EF Sbjct: 15 AFGLFDKDGDGCITVEELATVIRSL-DQNPTEEELQDMISEV----DADGNGTIEFDEFL 69 Query: 155 AVVG 158 +++ Sbjct: 70 SLMA 73 Score = 33.5 bits (75), Expect = 0.052, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 4/65 (6%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVD 71 D D + L + FK D D +G +S E ++L E + V+++I D DG+G+V+ Sbjct: 78 DTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVN 137 Query: 72 FKEFI 76 ++EF+ Sbjct: 138 YEEFV 142 Score = 27.3 bits (59), Expect = 3.0, Method: Compositional matrix adjust. Identities = 12/21 (57%), Positives = 14/21 (66%) Query: 141 DKDGDGRISFEEFCAVVGGLD 161 DKDGDG I+ EE V+ LD Sbjct: 20 DKDGDGCITVEELATVIRSLD 40 >3U0K-A nrPDB Length = 442 Score = 80.5 bits (197), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 49/144 (34%), Positives = 83/144 (57%), Gaps = 9/144 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I + F D D G+++ +E + + L QNP +Q +I+ D DG+G +DF Sbjct: 301 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFP 360 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 EF+ +++ D E+++R AFR++D D +GYIS EL V+ NL + + V Sbjct: 361 EFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEEV 415 Query: 134 DKTIINADKDGDGRISFEEFCAVV 157 D+ I AD DGDG++++EEF ++ Sbjct: 416 DEMIREADIDGDGQVNYEEFVQMM 439 Score = 30.0 bits (66), Expect = 0.59, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 4/66 (6%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E +L E + V +I D DG+G+V+ Sbjct: 372 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 431 Query: 72 FKEFIE 77 ++EF++ Sbjct: 432 YEEFVQ 437 >1GGZ-A nrPDB Length = 148 Score = 78.6 bits (192), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 49/144 (34%), Positives = 80/144 (55%), Gaps = 9/144 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIF---DTDGNGEVDFK 73 +++ + F D D G ++ E + + L QNP + D+ D DGNG VDF Sbjct: 7 EQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFP 66 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 EF+ +++ D E+++R AFR++D D +G++S EL V+ + G L D + V Sbjct: 67 EFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRL-GEKLSDEE----V 121 Query: 134 DKTIINADKDGDGRISFEEFCAVV 157 D+ I AD DGDG++++EEF V+ Sbjct: 122 DEMIRAADTDGDGQVNYEEFVRVL 145 >5T7C-A nrPDB Length = 193 Score = 78.2 bits (191), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 46/131 (35%), Positives = 77/131 (58%), Gaps = 13/131 (9%) Query: 35 SGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKE 89 +G L+V+EF + P + + V FDT+G+G +DF+EFI +S S +G E Sbjct: 40 TGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTS-RGKLE 98 Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKM---MVGNNLK----DTQLQQIVDKTIINADK 142 QKL++AF +YD+D +GYIS E+ ++++ MV + +K ++ ++ DK D Sbjct: 99 QKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDT 158 Query: 143 DGDGRISFEEF 153 + DG++S EEF Sbjct: 159 NNDGKLSLEEF 169 Score = 28.5 bits (62), Expect = 1.6, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 18/24 (75%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFM 44 KR K F+++D +N G LS+EEF+ Sbjct: 147 KRTDKIFRQMDTNNDGKLSLEEFI 170 Score = 27.7 bits (60), Expect = 2.5, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 18/76 (23%) Query: 21 KRLGKRFKKLDLDNSGSLS--------------VEEFMSLPELQQNPLVQRVIDIF---D 63 ++L F DLD +G +S V M +PE + P +R IF D Sbjct: 99 QKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTP-EKRTDKIFRQMD 157 Query: 64 TDGNGEVDFKEFIEGV 79 T+ +G++ +EFI G Sbjct: 158 TNNDGKLSLEEFIRGA 173 >2ZFD-A nrPDB Length = 226 Score = 78.2 bits (191), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 52/151 (34%), Positives = 88/151 (58%), Gaps = 8/151 (5%) Query: 15 FDADEIKRLGKRFKKLD--LDNSGSLSVEEF-MSLPEL--QQNPLVQRVIDIFDTDGNGE 69 F EI+ L + FKK+ + + G ++ EEF ++L + +++ RV D+FDT NG Sbjct: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI 101 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV---GNNLKD 126 + F+EF +S F + K+ F+F++YD+ + G+I E+ Q++ + G NLKD Sbjct: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 T ++ I+DKT AD DG+I EE+ ++V Sbjct: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 >1UHN-A nrPDB Length = 189 Score = 78.2 bits (191), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 52/151 (34%), Positives = 88/151 (58%), Gaps = 8/151 (5%) Query: 15 FDADEIKRLGKRFKKLD--LDNSGSLSVEEF-MSLPEL--QQNPLVQRVIDIFDTDGNGE 69 F EI+ L + FKK+ + + G ++ EEF ++L + +++ RV D+FDT NG Sbjct: 11 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI 70 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV---GNNLKD 126 + F+EF +S F + K+ F+F++YD+ + G+I E+ Q++ + G NLKD Sbjct: 71 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 130 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 T ++ I+DKT AD DG+I EE+ ++V Sbjct: 131 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 161 >1BJF-A nrPDB Length = 193 Score = 76.6 bits (187), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 46/131 (35%), Positives = 76/131 (58%), Gaps = 13/131 (9%) Query: 35 SGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKE 89 SG LS+EEF + P + + V FD +G+G +DF+EFI +S S +G E Sbjct: 40 SGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTS-RGKLE 98 Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKM---MVGNNLK----DTQLQQIVDKTIINADK 142 QKL++AF +YD+D +GYIS E+ ++++ MV + +K ++ ++ +K D Sbjct: 99 QKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDT 158 Query: 143 DGDGRISFEEF 153 + DG++S EEF Sbjct: 159 NRDGKLSLEEF 169 Score = 28.1 bits (61), Expect = 2.0, Method: Compositional matrix adjust. Identities = 19/75 (25%), Positives = 33/75 (44%), Gaps = 16/75 (21%) Query: 21 KRLGKRFKKLDLDNSGSLS--------------VEEFMSLPELQQNP--LVQRVIDIFDT 64 ++L F DLD +G +S V M +PE + P +++ DT Sbjct: 99 QKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDT 158 Query: 65 DGNGEVDFKEFIEGV 79 + +G++ +EFI G Sbjct: 159 NRDGKLSLEEFIRGA 173 >1CLM-A nrPDB Length = 148 Score = 75.9 bits (185), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 50/144 (34%), Positives = 82/144 (56%), Gaps = 9/144 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I + F D D G+++ +E + + L QNP +Q +I+ D DGNG +DF Sbjct: 7 EQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 66 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 EF+ +++ + D E++L AF+++D D +G IS EL V+ + G L D + V Sbjct: 67 EFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNL-GEKLTDDE----V 121 Query: 134 DKTIINADKDGDGRISFEEFCAVV 157 D+ I AD DGDG I++EEF ++ Sbjct: 122 DEMIREADIDGDGHINYEEFVRMM 145 >4I2Y-A nrPDB Length = 421 Score = 75.5 bits (184), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 53/161 (32%), Positives = 87/161 (54%), Gaps = 14/161 (8%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ 56 MG EA+ ++I + F D D G+++ +E + + L QNP +Q Sbjct: 268 MGWEATR-----DQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ 322 Query: 57 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL 116 +I+ D DG+G DF EF+ +++ D E+++R AFR++D D +GYI EL V+ Sbjct: 323 DMINEVDADGDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVM 382 Query: 117 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + G L D + VD+ I AD DGDG++++EEF ++ Sbjct: 383 TDL-GEKLTDEE----VDEMIRVADIDGDGQVNYEEFVQMM 418 >2LM5-A nrPDB Length = 214 Score = 73.9 bits (180), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 38/128 (29%), Positives = 71/128 (55%), Gaps = 5/128 (3%) Query: 36 GSLSVEEFMSLPELQQNPLVQRVIDIFDTD-GNGEVDFKEFIEGVSQFSVKGDKEQKLRF 94 + E+ +SLPEL+ NP +R+ +F T + F++F++ +S FS + K + Sbjct: 74 AQVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHY 133 Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVG----NNLKDTQLQQIVDKTIINADKDGDGRISF 150 AFRI+D D DG ++ +L +++ + G L ++++Q++D + +D D DG I+ Sbjct: 134 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 193 Query: 151 EEFCAVVG 158 EF V+ Sbjct: 194 SEFQHVIS 201 >1DGU-A nrPDB Length = 183 Score = 73.9 bits (180), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 38/128 (29%), Positives = 71/128 (55%), Gaps = 5/128 (3%) Query: 36 GSLSVEEFMSLPELQQNPLVQRVIDIFDTD-GNGEVDFKEFIEGVSQFSVKGDKEQKLRF 94 + E+ +SLPEL+ NP +R+ +F T + F++F++ +S FS + K + Sbjct: 43 AQVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHY 102 Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVG----NNLKDTQLQQIVDKTIINADKDGDGRISF 150 AFRI+D D DG ++ +L +++ + G L ++++Q++D + +D D DG I+ Sbjct: 103 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 162 Query: 151 EEFCAVVG 158 EF V+ Sbjct: 163 SEFQHVIS 170 >1V1G-A nrPDB Length = 222 Score = 72.8 bits (177), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 45/160 (28%), Positives = 85/160 (53%), Gaps = 8/160 (5%) Query: 2 GNEASYPLEMCSHFDADEIKRLGKRFKKLD--LDNSGSLSVEEF---MSLPELQQNPLVQ 56 G E L + F +E++ L + FKKL + + G + EEF + ++N Sbjct: 18 GYEDPELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQLALFRNRNRRNLFAD 77 Query: 57 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL 116 R+ D+FD NG ++F EF+ + F +K++FAF++YD+ + G+I EL +++ Sbjct: 78 RIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELKEMV 137 Query: 117 KMMVGNN---LKDTQLQQIVDKTIINADKDGDGRISFEEF 153 ++ + L + ++ +VDK + AD+ DG+I +E+ Sbjct: 138 VALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEW 177 >2L2E-A nrPDB Length = 190 Score = 72.8 bits (177), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 58/175 (33%), Positives = 94/175 (53%), Gaps = 24/175 (13%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGN 67 + FD E+++ K F K D SG L+ EF + P + + V ++FD D N Sbjct: 20 TRFDKKELQQWYKGFFK-DCP-SGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKN 77 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MVGNNL 124 G +DFKEFI +S S +G+ KL +AF++YD+D +G IS E+ +++ MVG+ + Sbjct: 78 GYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMV 136 Query: 125 K-----DTQLQQIVDKTIINADKDGDGRISFEEFC-------AVVGGLDIHKKMV 167 K DT ++ V+K DK+ DG+++ EEFC +V L ++ +V Sbjct: 137 KLPEDEDTP-EKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 >5UKG-A nrPDB Length = 419 Score = 72.4 bits (176), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 48/144 (33%), Positives = 81/144 (56%), Gaps = 9/144 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I + F D D G+++ +E + + L QNP +Q +I+ D DG+G DF Sbjct: 278 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFP 337 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 EF+ +++ E+++R AFR++D D +GYI EL V+ + G L D + V Sbjct: 338 EFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDL-GEKLTDEE----V 392 Query: 134 DKTIINADKDGDGRISFEEFCAVV 157 D+ I AD DGDG++++EEF ++ Sbjct: 393 DEMIRVADIDGDGQVNYEEFVQMM 416 >6EPA-A nrPDB Length = 187 Score = 72.0 bits (175), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 50/156 (32%), Positives = 86/156 (55%), Gaps = 14/156 (8%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 L ++F EI++ K F K D N G L+ + F+ + P+ + V +FD Sbjct: 16 LTTDTYFTEKEIRQWHKGFLK-DCPN-GLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFD 73 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV---LKMMV 120 + +G ++F+EFI +S + +G+ ++KL +AFR+YD+D DGYI+ E++ + + MV Sbjct: 74 ENNDGAIEFEEFIRALS-ITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMV 132 Query: 121 GNNLK---DTQLQQIVDKTIINADKDGDGRISFEEF 153 G + + Q+ VDK DK+ D R++ EEF Sbjct: 133 GQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEF 168 >2LCP-A nrPDB Length = 190 Score = 71.2 bits (173), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 39/124 (31%), Positives = 74/124 (59%), Gaps = 15/124 (12%) Query: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV-- 115 V ++FD + +G ++F EFI+ +S S +G ++KLR+AF++YD+D DGYI+ E+ + Sbjct: 68 VFNVFDENKDGRIEFSEFIQALSVTS-RGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVD 126 Query: 116 -LKMMVGNNL----KDTQLQQIVDKTIINADKDGDGRISFEEF-------CAVVGGLDIH 163 + MVGN + ++ ++ VD+ DK+ DG+++ +EF ++V L ++ Sbjct: 127 AIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLY 186 Query: 164 KKMV 167 +V Sbjct: 187 DGLV 190 Score = 32.0 bits (71), Expect = 0.15, Method: Compositional matrix adjust. Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 5/94 (5%) Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 +G++D F + QF GD + F F ++D +KDG I E Q L + L D Sbjct: 40 SGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTL-D 98 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 +L+ D D DG I+ E +V + Sbjct: 99 EKLRWAFKL----YDLDNDGYITRNEMLDIVDAI 128 Score = 30.4 bits (67), Expect = 0.35, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 18/86 (20%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM--------------SLPELQQNP- 53 L + S DE +L FK DLDN G ++ E + LPE + P Sbjct: 89 LSVTSRGTLDE--KLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPE 146 Query: 54 -LVQRVIDIFDTDGNGEVDFKEFIEG 78 V R+ + D + +G++ +EF EG Sbjct: 147 KRVDRIFAMMDKNADGKLTLQEFQEG 172 >3DD4-A nrPDB Length = 229 Score = 70.1 bits (170), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 53/162 (32%), Positives = 87/162 (53%), Gaps = 15/162 (9%) Query: 4 EASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRV 58 EA LE S F E++ L + FK + SG ++ E F + P+ + Sbjct: 50 EALELLEAQSKFTKKELQILYRGFK--NECPSGVVNEETFKEIYSQFFPQGDSTTYAHFL 107 Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 + FDTD NG V F++FI+G+S ++G ++KL +AF +YD++KDGYI+ E+ ++K Sbjct: 108 FNAFDTDHNGAVSFEDFIKGLS-ILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA 166 Query: 119 ---MVGNN----LKDTQLQQIVDKTIINADKDGDGRISFEEF 153 M+G LK+ +Q V+ DK+ DG ++ +EF Sbjct: 167 IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEF 208 >4DS7-A nrPDB Length = 147 Score = 69.7 bits (169), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 47/152 (30%), Positives = 78/152 (51%), Gaps = 10/152 (6%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIF---DTDG 66 M + ++I + F D DNSGS+S E + + L +P V D+ D DG Sbjct: 1 MSQNLTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEAEVADLMNEIDVDG 60 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 N ++F EF+ +S+ D EQ+L AF+++D + DG IS EL VL +G L D Sbjct: 61 NHAIEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLT-SIGEKLTD 119 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 ++ +++ + DG G I+ ++F A++ Sbjct: 120 AEVDEMLREV-----SDGSGEINIKQFAALLS 146 >2JU0-A nrPDB Length = 190 Score = 69.7 bits (169), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 52/178 (29%), Positives = 91/178 (51%), Gaps = 22/178 (12%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 L+ ++FD EI++ K F L SG L+ E+F+ + P + +FD Sbjct: 16 LKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL-------FQVL 116 D NG + F+EFI +S S +G E+KL +AF +YD++ DGYI+ E+ ++++ Sbjct: 74 KDNNGFIHFEEFITVLSTTS-RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 Query: 117 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF-------CAVVGGLDIHKKMV 167 MV N + + V K DK+ DG I+ +EF +++G L+++ ++ Sbjct: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI 190 >5M6C-E nrPDB Length = 193 Score = 68.9 bits (167), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 44/131 (33%), Positives = 75/131 (57%), Gaps = 13/131 (9%) Query: 35 SGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKE 89 +G L+V+EF + P + + V FDT+ +G +DF+EFI +S S +G E Sbjct: 40 TGILNVDEFKKIYANFFPYGDASKFAEHVFRNFDTNSDGTIDFREFIIALSVTS-RGRLE 98 Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKM---MVGNNLK----DTQLQQIVDKTIINADK 142 QKL +AF +YD+D +GYIS E+ ++++ MV + +K ++ ++ +K D Sbjct: 99 QKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDT 158 Query: 143 DGDGRISFEEF 153 + DG++S EEF Sbjct: 159 NNDGKLSLEEF 169 Score = 29.6 bits (65), Expect = 0.66, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 34/75 (45%), Gaps = 16/75 (21%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEF--------------MSLPELQQNP--LVQRVIDIFDT 64 ++L F DLD +G +S EE M +PE + P +++ DT Sbjct: 99 QKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDT 158 Query: 65 DGNGEVDFKEFIEGV 79 + +G++ +EFI G Sbjct: 159 NNDGKLSLEEFIRGA 173 >2TN4-A nrPDB Length = 159 Score = 68.6 bits (166), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 12/158 (7%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPE-LQQNPLVQR---VIDIFDTD 65 E S+ + I F D D G +SV+E ++ L Q P + +I+ D D Sbjct: 6 EARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDED 65 Query: 66 GNGEVDFKEF-IEGVSQFS--VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 G+G +DF+EF + V Q KG E++L FRI+D + DGYI EL ++ + G Sbjct: 66 GSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFR-ASGE 124 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 ++ D +++ ++ + DK+ DGRI F+EF ++ G+ Sbjct: 125 HVTDEEIESLMK----DGDKNNDGRIDFDEFLKMMEGV 158 >2LMV-A nrPDB Length = 148 Score = 68.2 bits (165), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 47/149 (31%), Positives = 83/149 (55%), Gaps = 9/149 (6%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-PELQQNPL---VQRVIDIFDTDGNG 68 S ++I F + D + +G ++ E +L L QNP +Q +I + + NG Sbjct: 2 SELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNG 61 Query: 69 EVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQ 128 +++F EF +++ + D E+++R AF+I+D D DG+IS EL V+ + +G + D + Sbjct: 62 QLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVM-INLGEKVTDEE 120 Query: 129 LQQIVDKTIINADKDGDGRISFEEFCAVV 157 +D+ I AD DGDG I++EEF ++ Sbjct: 121 ----IDEMIREADFDGDGMINYEEFVWMI 145 Score = 26.2 bits (56), Expect = 7.8, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 4/70 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVD 71 + D + + + FK D D G +S E ++L E + + +I D DG+G ++ Sbjct: 78 ETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEKVTDEEIDEMIREADFDGDGMIN 137 Query: 72 FKEFIEGVSQ 81 ++EF+ +SQ Sbjct: 138 YEEFVWMISQ 147 >5ZOR-A nrPDB Length = 149 Score = 68.2 bits (165), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 48/140 (34%), Positives = 75/140 (53%), Gaps = 18/140 (12%) Query: 27 FKKLDLDNSGSLSVEE---------FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 F D D SG++ EE F LP + V+R + +T+ NG +++ EF Sbjct: 13 FNLFDADGSGAIDAEEMALAMKGLGFGDLPRDE----VERTVRSMNTNANGLIEYGEFER 68 Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTI 137 V + D +++ AF+++D+DK G IS L +V K++ G N D LQ++ I Sbjct: 69 MVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLL-GENPGDDVLQEM----I 123 Query: 138 INADKDGDGRISFEEFCAVV 157 AD+DGDG +SFEEF +V+ Sbjct: 124 AEADEDGDGEVSFEEFKSVM 143 >1LKJ-A nrPDB Length = 146 Score = 67.4 bits (163), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 10/151 (6%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIF---DTDGN 67 S+ ++I + F D DN+GS+S E + + L +P V D+ D DGN Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 60 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 +++F EF+ +S+ D EQ+L AF+++D + DG IS EL VL +G L D Sbjct: 61 HQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVL-TSIGEKLTDA 119 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 ++ ++ + DG G I+ ++F A++ Sbjct: 120 EVDDMLREV-----SDGSGEINIQQFAALLS 145 >2LHI-A nrPDB Length = 176 Score = 67.0 bits (162), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 46/150 (30%), Positives = 78/150 (52%), Gaps = 10/150 (6%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIF---DTDGN 67 S+ ++I + F D DN+GS+S E + + L +P V D+ D DGN Sbjct: 2 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 61 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 +++F EF+ +S+ D EQ+L AF+++D + DG IS EL VL +G L D Sbjct: 62 HQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVL-TSIGEKLTDA 120 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVV 157 ++ ++ + DG G I+ ++F A++ Sbjct: 121 EVDDMLREV-----SDGSGEINIQQFAALL 145 >3KF9-A nrPDB Length = 149 Score = 66.2 bits (160), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 44/135 (32%), Positives = 81/135 (60%), Gaps = 9/135 (6%) Query: 27 FKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVSQF 82 F D D SG++ +E +++ L P ++++I D DG+G +DF+EF++ ++ Sbjct: 14 FDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTIDFEEFLQMMTAK 73 Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 + D +++ AFR++D D+ G IS L +V K + G N+ D +LQ+++D+ AD+ Sbjct: 74 MGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKEL-GENMTDEELQEMIDE----ADR 128 Query: 143 DGDGRISFEEFCAVV 157 DGDG ++ EEF ++ Sbjct: 129 DGDGEVNEEEFFRIM 143 Score = 31.2 bits (69), Expect = 0.25, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 53/105 (50%), Gaps = 9/105 (8%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDF 72 +EIK++ +D D SG++ EEF+ + E + + +FD D G++ F Sbjct: 44 EEIKKM---IADIDKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISF 100 Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 117 K ++ V++ + +++L+ D D DG ++ E F+++K Sbjct: 101 KN-LKRVAKELGENMTDEELQEMIDEADRDGDGEVNEEEFFRIMK 144 Score = 28.1 bits (61), Expect = 2.1, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 4/64 (6%) Query: 25 KRFKKLDLDNSGSLSVEEFMSLP-ELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVS 80 K F+ D D +G +S + + EL +N +Q +ID D DG+GEV+ +EF + Sbjct: 85 KAFRLFDDDETGKISFKNLKRVAKELGENMTDEELQEMIDEADRDGDGEVNEEEFFRIMK 144 Query: 81 QFSV 84 + S+ Sbjct: 145 KTSL 148 >2R2I-A nrPDB Length = 198 Score = 66.2 bits (160), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 40/126 (31%), Positives = 70/126 (55%), Gaps = 8/126 (6%) Query: 35 SGSLSVEEFMSLPELQQ-----NPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKE 89 SG L++ EF L+ N V+++ + FD + +G +DF E++ +S +KG + Sbjct: 29 SGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDFNKDGYIDFMEYVAALS-LVLKGKVD 87 Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL--QQIVDKTIINADKDGDGR 147 QKLR+ F++YD+D +G I GEL ++K + N + + ++ + D +GDG Sbjct: 88 QKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGE 147 Query: 148 ISFEEF 153 +S EEF Sbjct: 148 LSLEEF 153 Score = 29.3 bits (64), Expect = 0.87, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 11/72 (15%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSL-----------PELQQNPLVQRVIDIFDTDGNGE 69 ++L FK D+D +G + E +++ + V D D +G+GE Sbjct: 88 QKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGE 147 Query: 70 VDFKEFIEGVSQ 81 + +EF+EGV + Sbjct: 148 LSLEEFMEGVQK 159 >1TOP-A nrPDB Length = 162 Score = 64.7 bits (156), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 47/148 (31%), Positives = 80/148 (54%), Gaps = 12/148 (8%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPE-LQQNPLVQR---VIDIFDTDGNGEVDFKEF 75 I F D D G +S +E ++ L QNP + +I+ D DG+G +DF+EF Sbjct: 19 IAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEF 78 Query: 76 -IEGVSQFS--VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQI 132 + V Q KG E++L FRI+D + DG+I EL ++L+ G ++ + ++ + Sbjct: 79 LVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILR-ATGEHVTEEDIEDL 137 Query: 133 VDKTIINADKDGDGRISFEEFCAVVGGL 160 + ++DK+ DGRI F+EF ++ G+ Sbjct: 138 MK----DSDKNNDGRIDFDEFLKMMEGV 161 >2JNF-A nrPDB Length = 158 Score = 63.5 bits (153), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 50/159 (31%), Positives = 82/159 (51%), Gaps = 14/159 (8%) Query: 12 CSHFDADEIKRLGKRFKKLDL-DNSGSLSVEEFMSLPEL----QQNPLVQRVIDIFDTDG 66 S ++++K L F+ + + SG +S ++ + E+ Q ++++ID FD G Sbjct: 4 VSKLSSNQVKLLETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLIDEFDPFG 63 Query: 67 NGEVDFKEF-IEGVSQFSVKGDKEQ---KLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 NG++DF F I G + + EQ +LR AFR+YD + +GYIS + ++L Sbjct: 64 NGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILA----- 118 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 L +T + +D I D DG G + FEEF V+ G D Sbjct: 119 ELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVMTGGD 157 >2GGM-A nrPDB Length = 172 Score = 63.5 bits (153), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 41/138 (29%), Positives = 83/138 (60%), Gaps = 9/138 (6%) Query: 30 LDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVK 85 D D +G++ V+E +++ L P ++++I D +G G+++F +F+ ++Q + Sbjct: 40 FDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSE 99 Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 D ++++ AF+++D D+ G IS L +V K + G NL D +LQ+++D+ AD+DGD Sbjct: 100 KDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-GENLTDEELQEMIDE----ADRDGD 154 Query: 146 GRISFEEFCAVVGGLDIH 163 G +S +EF ++ ++ Sbjct: 155 GEVSEQEFLRIMKKTSLY 172 Score = 28.9 bits (63), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 4/64 (6%) Query: 25 KRFKKLDLDNSGSLSVEEFMSLP-ELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVS 80 K FK D D +G +S + + EL +N +Q +ID D DG+GEV +EF+ + Sbjct: 108 KAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMK 167 Query: 81 QFSV 84 + S+ Sbjct: 168 KTSL 171 >2OBH-A nrPDB Length = 143 Score = 62.8 bits (151), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 42/135 (31%), Positives = 81/135 (60%), Gaps = 9/135 (6%) Query: 27 FKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVSQF 82 F D D +G++ V+E +++ L P ++++I D +G G+++F +F+ ++Q Sbjct: 12 FDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQK 71 Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 + D ++++ AF+++D D+ G IS L +V K + G NL D +LQ+++D AD+ Sbjct: 72 MSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-GENLTDEELQEMID----EADR 126 Query: 143 DGDGRISFEEFCAVV 157 DGDG +S +EF ++ Sbjct: 127 DGDGEVSEQEFLRIM 141 >1JBA-A nrPDB Length = 204 Score = 62.8 bits (151), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 44/154 (28%), Positives = 81/154 (52%), Gaps = 19/154 (12%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNP----LVQRVIDIFDTDGNGEVD 71 DA +++ K+F L+ SG+L + EF ++ N V+ + FDT+G+ +D Sbjct: 20 DAAQLQEWYKKF--LEECPSGTLFMHEFKRFFKVPDNEEATQYVEAMFRAFDTNGDNTID 77 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV------LKMMVGNNLK 125 F E++ ++ ++G E KL++ F+IYD D++G I EL + LK ++ Sbjct: 78 FLEYVAALN-LVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEVE 136 Query: 126 DTQ------LQQIVDKTIINADKDGDGRISFEEF 153 Q +++VD+ + D++GDG++S EF Sbjct: 137 AEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEF 170 Score = 26.6 bits (57), Expect = 6.0, Method: Compositional matrix adjust. Identities = 14/50 (28%), Positives = 25/50 (50%) Query: 32 LDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQ 81 L + S+ VE L +V R+ + D +G+G++ EF+EG + Sbjct: 127 LKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARR 176 >2NA0-A nrPDB Length = 205 Score = 62.4 bits (150), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 41/127 (32%), Positives = 69/127 (54%), Gaps = 9/127 (7%) Query: 35 SGSLSVEEFMSLPELQQ-NPL----VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKE 89 SG L++ EF L+ +P V+++ + FD + +G +DF E+ E +KG E Sbjct: 31 SGQLTLYEFRQFFGLKNLSPWASQYVEQMFETFDFNKDGYIDFMEY-EAALSLVLKGKVE 89 Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVG-NNLKDTQL--QQIVDKTIINADKDGDG 146 QKLR+ F++YD+D +G I EL +++ + N D+ + ++ D D +GDG Sbjct: 90 QKLRWYFKLYDVDGNGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDG 149 Query: 147 RISFEEF 153 +S EEF Sbjct: 150 ELSLEEF 156 Score = 28.5 bits (62), Expect = 1.4, Method: Compositional matrix adjust. Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 12/73 (16%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSL------------PELQQNPLVQRVIDIFDTDGNG 68 ++L FK D+D +G + +E +++ + V D +G+G Sbjct: 90 QKLRWYFKLYDVDGNGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDG 149 Query: 69 EVDFKEFIEGVSQ 81 E+ +EF+EGV + Sbjct: 150 ELSLEEFMEGVQK 162 >2LAP-A nrPDB Length = 167 Score = 62.4 bits (150), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 49/169 (28%), Positives = 87/169 (51%), Gaps = 16/169 (9%) Query: 1 MGNEASYPLEMCSHFD----ADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLV 55 MGN YPL S D +EI+ L + F++ D D G ++ + + + + P Sbjct: 1 MGNCVKYPLRNLSRKDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTE 60 Query: 56 QRVIDI---FDTDGNGEVDFKEFIE--GVSQFSVKGDK--EQKLRFAFRIYDMDKDGYIS 108 +I++ + + G VDF +F+E G + D ++LR AFR +D + DG IS Sbjct: 61 MELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEIS 120 Query: 109 NGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 EL + ++ ++G+ + +++I I + D +GDGR+ FEEF ++ Sbjct: 121 TSELREAMRKLLGHQVGHRDIEEI----IRDVDLNGDGRVDFEEFVRMM 165 Score = 34.3 bits (77), Expect = 0.024, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 44/76 (57%), Gaps = 5/76 (6%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 S++ ++ ++LR AFR +D DKDGYI+ +L ++ M G + +L ++ + +N Sbjct: 18 SLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTM-GYMPTEMELIELSQQINMNL-- 74 Query: 143 DGDGRISFEEFCAVVG 158 G + F++F ++G Sbjct: 75 --GGHVDFDDFVELMG 88 Score = 29.3 bits (64), Expect = 0.84, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 5/67 (7%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL----VQRVIDIFDTDGNGEVDFKE 74 +K L F++ D + G +S E ++ +L + + ++ +I D +G+G VDF+E Sbjct: 101 VKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEE 160 Query: 75 FIEGVSQ 81 F+ +S+ Sbjct: 161 FVRMMSR 167 >1S6C-A nrPDB Length = 183 Score = 62.4 bits (150), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 47/157 (29%), Positives = 81/157 (51%), Gaps = 15/157 (9%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 LE ++F E++ L + FK + SG ++ E F + P + + + FD Sbjct: 9 LEAQTNFTKRELQVLYRGFK--NECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFD 66 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MV 120 T G V F++F+ +S ++G +KLR+ F +YD++KDGYI+ E+ ++K M+ Sbjct: 67 TTQTGSVKFEDFVTALS-ILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMM 125 Query: 121 GNN----LKDTQLQQIVDKTIINADKDGDGRISFEEF 153 G LK+ +Q VD DK+ DG ++ +EF Sbjct: 126 GKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEF 162 >5YPX-A nrPDB Length = 223 Score = 62.4 bits (150), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 33/109 (30%), Positives = 63/109 (57%), Gaps = 5/109 (4%) Query: 49 LQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYIS 108 + ++ L+ RV FD D + + E++EG+S F ++G ++K+ + F ++D++ DGYIS Sbjct: 77 MTEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVF-LRGTLDEKMEYTFTVFDLNGDGYIS 135 Query: 109 NGELFQVLKMMVGNNLK----DTQLQQIVDKTIINADKDGDGRISFEEF 153 E+FQ+LK + D ++ +V+ + D D D R+S ++F Sbjct: 136 REEMFQMLKTCLVKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKKDF 184 >1S1E-A nrPDB Length = 224 Score = 62.4 bits (150), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 47/157 (29%), Positives = 81/157 (51%), Gaps = 15/157 (9%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 LE ++F E++ L + FK + SG ++ E F + P + + + FD Sbjct: 42 LEAQTNFTKRELQVLYRGFK--NECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFD 99 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MV 120 T G V F++F+ +S ++G +KLR+ F +YD++KDGYI+ E+ ++K M+ Sbjct: 100 TTQTGSVKFEDFVTALS-ILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMM 158 Query: 121 GNN----LKDTQLQQIVDKTIINADKDGDGRISFEEF 153 G LK+ +Q VD DK+ DG ++ +EF Sbjct: 159 GKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEF 195 >3NCG-A nrPDB Length = 486 Score = 62.4 bits (150), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 24/158 (15%) Query: 18 DEIKRLGKRFKKLDLDNSGSL-------SVEEFMSLPELQQNPLVQR-----------VI 59 DE K+L + F+KLD +N G L EFM L + N L+Q ++ Sbjct: 328 DETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLM 387 Query: 60 DIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM 119 + D DG+G +++ EFI ++ +E+ R AF+++D D G IS ELF++ Sbjct: 388 PLLDMDGSGSIEYSEFIASAIDRTILLSRERMER-AFKMFDKDGSGKISTKELFKLFS-Q 445 Query: 120 VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 ++++ +L+ I+++ D + DG + F EF ++ Sbjct: 446 ADSSIQMEELESIIEQ----VDNNKDGEVDFNEFVEML 479 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 6/67 (8%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEF 75 +R+ + FK D D SG +S +E L +Q L + +I+ D + +GEVDF EF Sbjct: 417 ERMERAFKMFDKDGSGKISTKELFKLFSQADSSIQMEEL-ESIIEQVDNNKDGEVDFNEF 475 Query: 76 IEGVSQF 82 +E + F Sbjct: 476 VEMLQNF 482 >2LHH-A nrPDB Length = 128 Score = 61.2 bits (147), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 41/123 (33%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIF---DTDGN 67 S+ ++I + F D DN+GS+S E + + L +P V D+ D DGN Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 60 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 +++F EF+ +S+ D EQ+L AF+++D + DG IS EL VL +G L D Sbjct: 61 HQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVL-TSIGEKLTDA 119 Query: 128 QLQ 130 +L+ Sbjct: 120 ELE 122 Score = 34.3 bits (77), Expect = 0.028, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 38/64 (59%), Gaps = 5/64 (7%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF ++D D +G IS+ EL V++ + G + + ++ ++++ D DG+ +I F EF Sbjct: 15 AFALFDKDNNGSISSSELATVMRSL-GLSPSEAEVNDLMNEI----DVDGNHQIEFSEFL 69 Query: 155 AVVG 158 A++ Sbjct: 70 ALMS 73 >5D43-A nrPDB Length = 178 Score = 61.2 bits (147), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 42/150 (28%), Positives = 87/150 (58%), Gaps = 9/150 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 D+ + + + F D D SG++ V+E +++ L P ++++I D + G++ F Sbjct: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 +F+ ++Q + D ++++ AFR++D D+ G IS L +V + G +L D +LQ+++ Sbjct: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEMI 146 Query: 134 DKTIINADKDGDGRISFEEFCAVVGGLDIH 163 D+ AD+DGDG ++ EEF ++ +++ Sbjct: 147 DE----ADRDGDGEVNEEEFLKIMKKTNLY 172 >2AAO-A nrPDB Length = 166 Score = 60.8 bits (146), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 44/144 (30%), Positives = 76/144 (52%), Gaps = 12/144 (8%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIF---DTDGNGEVDFK 73 +EI L + F +D D SG ++ EE + L + N ++D+ D D +G +D+K Sbjct: 24 EEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTIDYK 83 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 EFI + K ++E L AF +D D GYI+ EL Q + ++D ++++++ Sbjct: 84 EFIAATLHLN-KIEREDHLFAAFTYFDKDGSGYITPDELQQACEEF---GVEDVRIEELM 139 Query: 134 DKTIINADKDGDGRISFEEFCAVV 157 + D+D DGRI + EF A++ Sbjct: 140 R----DVDQDNDGRIDYNEFVAMM 159 Score = 33.9 bits (76), Expect = 0.041, Method: Compositional matrix adjust. Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 10/81 (12%) Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKT 136 E +S+ + G KE F + D DK G I+ EL LK VG NLK++++ ++ Sbjct: 19 ESLSEEEIAGLKEM-----FNMIDADKSGQITFEELKAGLK-RVGANLKESEILDLMQA- 71 Query: 137 IINADKDGDGRISFEEFCAVV 157 AD D G I ++EF A Sbjct: 72 ---ADVDNSGTIDYKEFIAAT 89 >2JUL-A nrPDB Length = 256 Score = 60.1 bits (144), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 65/115 (56%), Gaps = 8/115 (6%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDG 105 P+ + + FD DGNG + F++F+ G+S ++G +KL++AF +YD++KDG Sbjct: 122 FPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLS-ILLRGTVHEKLKWAFNLYDINKDG 180 Query: 106 YISNGELFQVLKM---MVGNN----LKDTQLQQIVDKTIINADKDGDGRISFEEF 153 I+ E+ ++K M+G + L++ + V++ D++ DG ++ +EF Sbjct: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 >1DTL-A nrPDB Length = 161 Score = 59.3 bits (142), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 43/133 (32%), Positives = 74/133 (55%), Gaps = 12/133 (9%) Query: 36 GSLSVEEFMSLPE-LQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVSQF---SVKGDK 88 GS+S +E + L QNP +Q +ID D DG+G VDF EF+ + + KG Sbjct: 34 GSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKS 93 Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRI 148 E++L FR++D + DGYI EL +++ G + + +++++ + DK+ DGRI Sbjct: 94 EEELSDLFRMFDKNADGYIDLEEL-KIMLQATGETITEDDIEELMK----DGDKNNDGRI 148 Query: 149 SFEEFCAVVGGLD 161 ++EF + G++ Sbjct: 149 DYDEFLEFMKGVE 161 >2JNX-A nrPDB Length = 134 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 42/135 (31%), Positives = 69/135 (51%), Gaps = 15/135 (11%) Query: 27 FKKLDLDNSGSLSVEEFMSLPE----LQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQF 82 FK+LD + GS+S EE + ++ L+Q + D DGNGE+D EF + + Sbjct: 6 FKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKFAAAV 65 Query: 83 SVK--GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA 140 + D++ L+ +++ D D DG ++ E V K +++VD+ I+ A Sbjct: 66 KEQDLSDEKVGLKILYKLMDADGDGKLTKEE--------VTTFFKKFGYEKVVDQ-IMKA 116 Query: 141 DKDGDGRISFEEFCA 155 D +GDG I+ EEF A Sbjct: 117 DANGDGYITLEEFLA 131 >1S6I-A nrPDB Length = 188 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 47/152 (30%), Positives = 76/152 (50%), Gaps = 16/152 (10%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDG 66 +EI L + FK +D DNSG+++ +E EL ++ ++ ++D D D Sbjct: 1 AERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESE-IKDLMDAADIDK 59 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 +G +D+ EFI + K ++E+ L AF +D D GYI+ E+ Q KD Sbjct: 60 SGTIDYGEFIAATVHLN-KLEREENLVSAFSYFDKDGSGYITLDEIQQA--------CKD 110 Query: 127 TQLQQI-VDKTIINADKDGDGRISFEEFCAVV 157 L I +D I D+D DG+I + EF A++ Sbjct: 111 FGLDDIHIDDMIKEIDQDNDGQIDYGEFAAMM 142 >3O4Y-A nrPDB Length = 196 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 44/145 (30%), Positives = 76/145 (52%), Gaps = 11/145 (7%) Query: 19 EIKRLGKRFKKLDLDNSGS---LSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEF 75 ++++L F LD + G+ L + + + L P ++D D+DG+G +D+ EF Sbjct: 53 DVQKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNFDLLLDQIDSDGSGNIDYTEF 112 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN---NLKDTQLQQI 132 + + + ++ + AFR++D+D DG I+ EL VL GN N+ + + Q Sbjct: 113 L--AAAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVL--FNGNKRGNITERDVNQ- 167 Query: 133 VDKTIINADKDGDGRISFEEFCAVV 157 V K I DK+GDG+I F EF ++ Sbjct: 168 VKKMIREVDKNGDGKIDFYEFSEMM 192 >4JWQ-A nrPDB Length = 199 Score = 57.8 bits (138), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 44/145 (30%), Positives = 75/145 (51%), Gaps = 11/145 (7%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQR---VIDIFDTDGNGEVDFKEF 75 ++++L F LD D G+++ + E L Q ++D D+DG+G +D+ EF Sbjct: 56 DLQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEF 115 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVD- 134 + + K ++ + AFR++D+D DG I+ EL +L N K + Q+ V+ Sbjct: 116 L--AAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHIL---YNGNKKGSITQKDVNQ 170 Query: 135 --KTIINADKDGDGRISFEEFCAVV 157 K I DK+ DG+I F EFC ++ Sbjct: 171 VKKMIQEVDKNNDGKIDFYEFCEMM 195 >2I94-A nrPDB Length = 202 Score = 57.0 bits (136), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 34/116 (29%), Positives = 60/116 (51%), Gaps = 8/116 (6%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 L++ + F +E+ + F L SG ++ +EF ++ PE Q V FD Sbjct: 17 LQLNTKFTEEELSSWYQSF--LKECPSGRITRQEFQTIYSKFFPEADPKAYAQHVFRSFD 74 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM 119 + +G +DFKE++ + S G QKL +AF +YD+D +G IS E+ +++ + Sbjct: 75 ANSDGTLDFKEYVIALHMTSA-GKTNQKLEWAFSLYDVDGNGTISKNEVLEIVTAI 129 Score = 29.6 bits (65), Expect = 0.67, Method: Compositional matrix adjust. Identities = 23/94 (24%), Positives = 39/94 (41%), Gaps = 5/94 (5%) Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 +G + +EF S+F + D + + FR +D + DG + E L M Sbjct: 41 SGRITRQEFQTIYSKFFPEADPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAG---- 96 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 + Q ++ D DG+G IS E +V + Sbjct: 97 -KTNQKLEWAFSLYDVDGNGTISKNEVLEIVTAI 129 >2GGZ-A nrPDB Length = 211 Score = 57.0 bits (136), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 40/125 (32%), Positives = 66/125 (52%), Gaps = 7/125 (5%) Query: 35 SGSLSVEEFMSLPELQ-----QNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKE 89 SG ++ EF +L LQ N + +V + FDT+ +G VDF EFI V+ ++ E Sbjct: 34 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN-LIMQEKME 92 Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT-QLQQIVDKTIINADKDGDGRI 148 QKL++ F++YD D +G I EL + + N + T ++ ++ D + DG + Sbjct: 93 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 152 Query: 149 SFEEF 153 + EEF Sbjct: 153 TLEEF 157 Score = 26.9 bits (58), Expect = 4.9, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 10/71 (14%) Query: 21 KRLGKRFKKLDLDNSGSLSVEE----FMSLPEL--QQNPLVQRVIDI----FDTDGNGEV 70 ++L FK D D +GS+ E FM++ L QQ + I++ D + +GE+ Sbjct: 93 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 152 Query: 71 DFKEFIEGVSQ 81 +EFI G+++ Sbjct: 153 TLEEFINGMAK 163 >2RO9-A nrPDB Length = 69 Score = 55.8 bits (133), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 31/71 (43%), Positives = 47/71 (66%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D E++L+ AFR++D D++G+IS EL V+ + G L D + VD+ I AD DGDG Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNL-GEKLTDEE----VDEMIREADVDGDG 55 Query: 147 RISFEEFCAVV 157 +I++EEF V+ Sbjct: 56 QINYEEFVKVM 66 Score = 27.7 bits (60), Expect = 2.5, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 4/63 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFK 73 D + L + F+ D D +G +S E +L E + V +I D DG+G+++++ Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 74 EFI 76 EF+ Sbjct: 61 EFV 63 >3QRX-A nrPDB Length = 169 Score = 55.5 bits (132), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 40/135 (29%), Positives = 75/135 (55%), Gaps = 9/135 (6%) Query: 27 FKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVSQF 82 F D D SG++ +E +++ L P ++++I D DG+G +DF+EF+ ++ Sbjct: 34 FDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAK 93 Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 + D +++ AFR++D D G I+ +L +V K + G NL + +LQ++ I AD+ Sbjct: 94 MGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKEL-GENLTEEELQEM----IAEADR 148 Query: 143 DGDGRISFEEFCAVV 157 + D I +EF ++ Sbjct: 149 NDDNEIDEDEFIRIM 163 >1FW4-A nrPDB Length = 71 Score = 55.1 bits (131), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 29/71 (40%), Positives = 45/71 (63%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D E+++R AFR++D D +GYIS EL V+ NL + + VD+ I AD DGDG Sbjct: 3 DSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEEVDEMIREADIDGDG 57 Query: 147 RISFEEFCAVV 157 ++++EEF ++ Sbjct: 58 QVNYEEFVQMM 68 Score = 30.0 bits (66), Expect = 0.52, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 4/66 (6%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E +L E + V +I D DG+G+V+ Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 60 Query: 72 FKEFIE 77 ++EF++ Sbjct: 61 YEEFVQ 66 >2HF5-A nrPDB Length = 68 Score = 54.7 bits (130), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 26/62 (41%), Positives = 41/62 (66%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 +Q +I+ D DGNG +DF EF+ +++ D E+++R AFR++D D +GYIS EL Sbjct: 3 LQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRH 62 Query: 115 VL 116 V+ Sbjct: 63 VM 64 >3K21-A nrPDB Length = 191 Score = 54.7 bits (130), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 43/145 (29%), Positives = 75/145 (51%), Gaps = 11/145 (7%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPE---LQQNPLVQRVIDIFDTDGNGEVDFKEF 75 ++++L F LD D G ++ E+ E L+ ++D D+DG+G++D+ EF Sbjct: 50 DVEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEF 109 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDK 135 I + K ++ + AFR++D+D DG I+ EL +L N K Q+ V++ Sbjct: 110 I--AAALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHIL---YNGNKKGNITQRDVNR 164 Query: 136 T---IINADKDGDGRISFEEFCAVV 157 I + DK+ DG+I F EF ++ Sbjct: 165 VKRMIRDVDKNNDGKIDFHEFSEMM 189 >2KN2-A nrPDB Length = 92 Score = 54.3 bits (129), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 27/71 (38%), Positives = 50/71 (70%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D E++L+ AF+++D D++GYIS EL V+ + +G L D +++Q++ + AD DGDG Sbjct: 6 DAEEELKEAFKVFDKDQNGYISASELRHVM-INLGEKLTDEEVEQMIKE----ADLDGDG 60 Query: 147 RISFEEFCAVV 157 ++++EEF ++ Sbjct: 61 QVNYEEFVKMM 71 Score = 37.0 bits (84), Expect = 0.004, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 4/67 (5%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGE 69 H D D + L + FK D D +G +S E ++L E + V+++I D DG+G+ Sbjct: 2 HMDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQ 61 Query: 70 VDFKEFI 76 V+++EF+ Sbjct: 62 VNYEEFV 68 >2ROB-A nrPDB Length = 70 Score = 54.3 bits (129), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 27/71 (38%), Positives = 50/71 (70%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D E++L+ AF+++D D++GYIS EL V+ + +G L D +++Q++ + AD DGDG Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVM-INLGEKLTDEEVEQMIKE----ADLDGDG 55 Query: 147 RISFEEFCAVV 157 ++++EEF ++ Sbjct: 56 QVNYEEFVKMM 66 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 38/65 (58%), Gaps = 6/65 (9%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVD 71 DA+E L + FK D D +G +S E ++L E + V+++I D DG+G+V+ Sbjct: 1 DAEE--ELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVN 58 Query: 72 FKEFI 76 ++EF+ Sbjct: 59 YEEFV 63 >4MVF-A nrPDB Length = 506 Score = 53.5 bits (127), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 40/155 (25%), Positives = 77/155 (49%), Gaps = 8/155 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM----SLPELQQNPLVQRVIDIFDTDG 66 + H EI L F LD+DNSG+LS +E + + + P + +V+ D++ Sbjct: 350 IAKHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNA 409 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 +G++ + +F+ KE L F+ +D+D +G IS EL ++ +++++ Sbjct: 410 SGQIHYTDFLAATIDKQTYLKKEVCL-IPFKFFDIDGNGKISVEELKRIFGR---DDIEN 465 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 + + +D + D +GDG I F EF ++ L+ Sbjct: 466 PLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKLE 500 >2LC5-A nrPDB Length = 151 Score = 53.5 bits (127), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 41/134 (30%), Positives = 74/134 (55%), Gaps = 10/134 (7%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDI---FDTDGNGEVDF 72 A+E + + F+ D DN L+ EE + + L NP Q++ +I +D D +G+ D Sbjct: 10 AEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKDNSGKFDQ 69 Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQ---- 128 + F+ + ++ + D + ++ AF I+D +K+GYIS EL VL + G L + + Sbjct: 70 ETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTTL-GEKLTEQEVDDL 128 Query: 129 LQQI-VDKTIINAD 141 L++I V++ +IN D Sbjct: 129 LKEIGVEEGLINVD 142 Score = 33.1 bits (74), Expect = 0.065, Method: Compositional matrix adjust. Identities = 18/74 (24%), Positives = 39/74 (52%), Gaps = 5/74 (6%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 + +++Q+ + AF+++D D D ++ EL V++ + N K Q + + + + DKD Sbjct: 8 LTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTK-----QKISEIVKDYDKD 62 Query: 144 GDGRISFEEFCAVV 157 G+ E F ++ Sbjct: 63 NSGKFDQETFLTIM 76 >2KZ2-A nrPDB Length = 94 Score = 53.1 bits (126), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 30/71 (42%), Positives = 45/71 (63%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D E+++R AFR+ D D +GYIS EL V+ + G L D + VD+ I AD DGDG Sbjct: 26 DSEEEIREAFRVEDKDGNGYISAAELRHVMTNL-GEKLTDEE----VDEMIREADIDGDG 80 Query: 147 RISFEEFCAVV 157 ++++EEF ++ Sbjct: 81 QVNYEEFVQMM 91 Score = 28.5 bits (62), Expect = 1.3, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 4/66 (6%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E +L E + V +I D DG+G+V+ Sbjct: 24 DTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 83 Query: 72 FKEFIE 77 ++EF++ Sbjct: 84 YEEFVQ 89 >2M29-A nrPDB Length = 171 Score = 53.1 bits (126), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 34/95 (35%), Positives = 54/95 (56%), Gaps = 8/95 (8%) Query: 67 NGEVDFKEFIEGVS----QFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 G VDF+EF+E +S + + ++LR AFR +D D+DG I+ EL Q ++G Sbjct: 78 GGFVDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGE 137 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 L+ T+L D+ + D +GDG I F+EF ++ Sbjct: 138 PLEGTEL----DEMLREMDLNGDGTIDFDEFVMML 168 Score = 30.8 bits (68), Expect = 0.34, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 5/62 (8%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPL----VQRVIDIFDTDGNGEVDFKE 74 ++ L F++ D D G ++V E + P L PL + ++ D +G+G +DF E Sbjct: 104 VRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTIDFDE 163 Query: 75 FI 76 F+ Sbjct: 164 FV 165 >2D8N-A nrPDB Length = 207 Score = 52.8 bits (125), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 12/126 (9%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 L++ + F +E+ + F L +G ++ ++F S+ P+ Q V FD Sbjct: 24 LQLNTKFSEEELCSWYQSF--LKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVFRSFD 81 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL----KMM 119 ++ +G +DFKE++ + + G QKL +AF +YD+D +G IS E+ +++ KM+ Sbjct: 82 SNLDGTLDFKEYVIAL-HMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMI 140 Query: 120 VGNNLK 125 ++K Sbjct: 141 TPEDVK 146 >3PM8-A nrPDB Length = 197 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 39/147 (26%), Positives = 73/147 (49%), Gaps = 8/147 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM----SLPELQQNPLVQRVIDIFDTDG 66 + H EI L F LD+DNSG+LS +E + + + P + +V+ D++ Sbjct: 47 IAKHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNA 106 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 +G++ + +F+ KE L F+ +D+D +G IS EL ++ +++++ Sbjct: 107 SGQIHYTDFLAATIDKQTYLKKEVCL-IPFKFFDIDGNGKISVEELKRIFGR---DDIEN 162 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEF 153 + + +D + D +GDG I F EF Sbjct: 163 PLIDKAIDSLLQEVDLNGDGEIDFHEF 189 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/61 (37%), Positives = 37/61 (60%), Gaps = 6/61 (9%) Query: 27 FKKLDLDNSGSLSVEEFMSL--PELQQNPLVQRVIDIF----DTDGNGEVDFKEFIEGVS 80 FK D+D +G +SVEE + + +NPL+ + ID D +G+GE+DF EF+ +S Sbjct: 135 FKFFDIDGNGKISVEELKRIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMS 194 Query: 81 Q 81 + Sbjct: 195 K 195 >1JFJ-A nrPDB Length = 134 Score = 51.6 bits (122), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 41/134 (30%), Positives = 72/134 (53%), Gaps = 15/134 (11%) Query: 27 FKKLDLDNSGSLSVEE---FMSLPELQQNP-LVQRVIDIFDTDGNGEVDFKEFIE--GVS 80 FK++D++ G++S EE F+S +N L+Q + D DGNGE+D EF + G Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFYGSI 65 Query: 81 QFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA 140 Q D + L+ +++ D+D DG ++ E V + K ++++ ++ ++ A Sbjct: 66 QGQDLSDDKIGLKVLYKLMDVDGDGKLTKEE--------VTSFFKKHGIEKVAEQ-VMKA 116 Query: 141 DKDGDGRISFEEFC 154 D +GDG I+ EEF Sbjct: 117 DANGDGYITLEEFL 130 Score = 27.3 bits (59), Expect = 3.0, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 9/67 (13%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNN--LKDTQLQQIVDKTIINADKDGDGRISFEEF 153 F+ D++ DG +S ++ +K V +K+ QL Q++ K+I D DG+G I EF Sbjct: 6 FKEIDVNGDGAVS----YEEVKAFVSKKRAIKNEQLLQLIFKSI---DADGNGEIDQNEF 58 Query: 154 CAVVGGL 160 G + Sbjct: 59 AKFYGSI 65 >1M39-A nrPDB Length = 89 Score = 50.1 bits (118), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 30/94 (31%), Positives = 59/94 (62%), Gaps = 5/94 (5%) Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 ++F +F+ ++Q + D ++++ AF+++D D+ G IS L +V K + G NL D +L Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-GENLTDEEL 59 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 Q+++D+ AD+DGDG +S +EF ++ ++ Sbjct: 60 QEMIDE----ADRDGDGEVSEQEFLRIMKKTSLY 89 Score = 29.3 bits (64), Expect = 0.94, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 4/64 (6%) Query: 25 KRFKKLDLDNSGSLSVEEFMSLP-ELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVS 80 K FK D D +G +S + + EL +N +Q +ID D DG+GEV +EF+ + Sbjct: 25 KAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMK 84 Query: 81 QFSV 84 + S+ Sbjct: 85 KTSL 88 >2K2I-A nrPDB Length = 79 Score = 48.5 bits (114), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 31/85 (36%), Positives = 52/85 (61%), Gaps = 6/85 (7%) Query: 79 VSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII 138 + S K KE+ L+ AF+++D D+ G IS L +V K + G NL D +LQ+++D+ Sbjct: 1 TQKMSEKDTKEEILK-AFKLFDDDETGKISFKNLKRVAKEL-GENLTDEELQEMIDE--- 55 Query: 139 NADKDGDGRISFEEFCAVVGGLDIH 163 AD+DGDG +S +EF ++ ++ Sbjct: 56 -ADRDGDGEVSEQEFLRIMKKTSLY 79 Score = 29.3 bits (64), Expect = 0.92, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 4/64 (6%) Query: 25 KRFKKLDLDNSGSLSVEEFMSLP-ELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVS 80 K FK D D +G +S + + EL +N +Q +ID D DG+GEV +EF+ + Sbjct: 15 KAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMK 74 Query: 81 QFSV 84 + S+ Sbjct: 75 KTSL 78 >2K2A-A nrPDB Length = 70 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 5/73 (6%) Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRI 148 +Q+LR AFR+YD + +GYIS + ++L L +T + +D I D DG G + Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILA-----ELDETLSSEDLDAMIDEIDADGSGTV 56 Query: 149 SFEEFCAVVGGLD 161 FEEF V+ G D Sbjct: 57 DFEEFMGVMTGGD 69 Score = 29.3 bits (64), Expect = 0.94, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSV----EEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 76 + L + F+ D + +G +S E L E + + +ID D DG+G VDF+EF+ Sbjct: 3 QELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFM 62 >3AAJ-A nrPDB Length = 167 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 49/156 (31%), Positives = 69/156 (44%), Gaps = 23/156 (14%) Query: 23 LGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL----VQRVIDIFDTDGNGEVDFKEFIE 77 L F+++D D SG +S E +L P V+ +I +FD + V+F EF Sbjct: 6 LWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEF-T 64 Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTI 137 GV ++ FR YD D G I EL Q L G L D Q D I Sbjct: 65 GVWKYITDWQN------VFRTYDRDNSGMIDKNELKQALS---GYRLSD----QFHDILI 111 Query: 138 INADKDGDGRISFEEF---CAVVGGL-DIHKKMVVD 169 D+ G G+I+F++F C V+ L DI ++ D Sbjct: 112 RKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTD 147 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 17/87 (19%) Query: 27 FKKLDLDNSGSLSVEEF------MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVS 80 F+ D DNSG + E L + + L+++ FD G G++ F +FI+G Sbjct: 77 FRTYDRDNSGMIDKNELKQALSGYRLSDQFHDILIRK----FDRQGRGQIAFDDFIQGCI 132 Query: 81 QFSVKGDKEQKLRFAFRIYDMDKDGYI 107 Q+L FR YD D+DG+I Sbjct: 133 VL-------QRLTDIFRRYDTDQDGWI 152 >4YZB-A nrPDB Length = 491 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 33/156 (21%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS------------LPELQQNPL---VQRVIDIF 62 +E L K F+++D + G L +E M + L Q+ + V++V+D Sbjct: 336 EETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLDAV 395 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKE-----QKLRFAFRIYDMDKDGYISNGELFQVLK 117 D D NG +++ EF+ +V D++ Q+L AF ++D D G IS+ EL + Sbjct: 396 DFDKNGFIEYSEFV------TVAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIF- 448 Query: 118 MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 G + D++ + + + D++ DG + FEEF Sbjct: 449 ---GVSEVDSETWR---RVLAEVDRNNDGEVDFEEF 478 Score = 32.7 bits (73), Expect = 0.074, Method: Compositional matrix adjust. Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 19/120 (15%) Query: 49 LQQNPLVQRVIDIFDTDGNGEVDFKEFIEG-VSQFSVKGDKEQKL---RFAFRI------ 98 ++ N + QR+ D +G+G++D +E +EG V +KG+ L F + Sbjct: 339 VELNKIFQRM----DKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLDA 394 Query: 99 YDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 D DK+G+I E + V + K +Q +++ D DG G+IS E + G Sbjct: 395 VDFDKNGFIEYSEF-----VTVAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIFG 449 >2M5E-A nrPDB Length = 73 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 29/71 (40%), Positives = 43/71 (60%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D E++L AF+++D D +G IS EL V+ + G L D + VD+ I AD DGDG Sbjct: 5 DSEEELIEAFKVFDRDGNGLISAAELRHVMTNL-GEKLTDDE----VDEMIREADIDGDG 59 Query: 147 RISFEEFCAVV 157 I++EEF ++ Sbjct: 60 HINYEEFVRMM 70 Score = 26.9 bits (58), Expect = 4.0, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 4/63 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFK 73 D + L + FK D D +G +S E +L E + V +I D DG+G ++++ Sbjct: 5 DSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYE 64 Query: 74 EFI 76 EF+ Sbjct: 65 EFV 67 >2K7C-A nrPDB Length = 72 Score = 47.0 bits (110), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 24/68 (35%), Positives = 43/68 (63%), Gaps = 4/68 (5%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 ++LR AFR +D + DG IS EL + ++ ++G+ + +++I I + D +GDGR+ Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEI----IRDVDLNGDGRVD 62 Query: 150 FEEFCAVV 157 FEEF ++ Sbjct: 63 FEEFVRMM 70 Score = 29.6 bits (65), Expect = 0.65, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 5/67 (7%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL----VQRVIDIFDTDGNGEVDFKE 74 +K L F++ D + G +S E ++ +L + + ++ +I D +G+G VDF+E Sbjct: 6 VKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEE 65 Query: 75 FIEGVSQ 81 F+ +S+ Sbjct: 66 FVRMMSR 72 >3MSE-B nrPDB Length = 180 Score = 46.2 bits (108), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 41/146 (28%), Positives = 74/146 (50%), Gaps = 19/146 (13%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEE-FMSLPELQQNPL-VQRVIDIFDTDGNGEVDFKEF 75 + IK + + F KLD +++GSLS E + L + + R++ D + G + + EF Sbjct: 36 NHIKYINELFYKLDTNHNGSLSHREIYTVLASVGIKKWDINRILQALDINDRGNITYTEF 95 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL--KMMVGNNLKDTQL---- 129 + G ++ K + L+ AF D D+DGYIS ++ ++ K++ N++ + L Sbjct: 96 MAGCYRW--KNIESTFLKAAFNKIDKDEDGYISKSDIVSLVHDKVLDNNDIDNFFLSVHS 153 Query: 130 --QQIVDKTIINADKDGDGRISFEEF 153 + I + IIN +ISF+EF Sbjct: 154 IKKGIPREHIIN-------KISFQEF 172 >2BL0-B nrPDB Length = 145 Score = 46.2 bits (108), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 43/144 (29%), Positives = 74/144 (51%), Gaps = 20/144 (13%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIFDTDGNGEVDFKEF 75 AD+I+ F+ D DN G +S+EE S L L +NP + I G+++ KEF Sbjct: 4 ADQIQEC---FQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTI-----KGQLNAKEF 55 Query: 76 ----IEGVSQFSVKGDKEQKLRF--AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 + V + +K EQ AFR D + +G I EL Q+L + +G+ L +++ Sbjct: 56 DLATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLL-LNLGDALTSSEV 114 Query: 130 QQIVDKTIINADKDGDGRISFEEF 153 ++++ + ++ GDG I++E F Sbjct: 115 EELMKEVSVS----GDGAINYESF 134 >2LV7-A nrPDB Length = 100 Score = 46.2 bits (108), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 24/75 (32%), Positives = 46/75 (61%), Gaps = 5/75 (6%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 + D+ +++R AF+++D D +G+IS EL ++ + G + +L+ I+ + D D Sbjct: 30 IPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSL-GYMPNEVELEVIIQRL----DMD 84 Query: 144 GDGRISFEEFCAVVG 158 GDG++ FEEF ++G Sbjct: 85 GDGQVDFEEFVTLLG 99 Score = 34.3 bits (77), Expect = 0.031, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 4/63 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFK 73 DE++ + + FK D D +G +S +E SL + ++ +I D DG+G+VDF+ Sbjct: 33 DELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFE 92 Query: 74 EFI 76 EF+ Sbjct: 93 EFV 95 >3Q5I-A nrPDB Length = 504 Score = 46.2 bits (108), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 47/164 (28%), Positives = 76/164 (46%), Gaps = 30/164 (18%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-----------LPELQQ-NPLVQRVIDIFDTD 65 +E K L FKKLD + G L +E + L EL+ V ++ D D Sbjct: 352 EERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVDFD 411 Query: 66 GNGEVDFKEFIEGVSQFSVKGDK-----EQKLRFAFRIYDMDKDGYISNGELFQVLKMMV 120 NG +++ EFI SV DK E++LR AF ++D DK G I+ EL + + Sbjct: 412 KNGYIEYSEFI------SVCMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLFGLT- 464 Query: 121 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHK 164 + ++ + + AD++ D I F+EF +++ + HK Sbjct: 465 ------SISEKTWNDVLGEADQNKDNMIDFDEFVSMMHKICDHK 502 >2E6W-A nrPDB Length = 100 Score = 45.8 bits (107), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 46/78 (58%), Gaps = 7/78 (8%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MVGNN----LKDTQLQQIVDK 135 S G +KL++AF +YD++KDGYI+ E+ ++K M+G + L++ + V++ Sbjct: 2 SHMGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVER 61 Query: 136 TIINADKDGDGRISFEEF 153 D++ DG ++ EEF Sbjct: 62 FFEKMDRNQDGVVTIEEF 79 >3LIJ-A nrPDB Length = 494 Score = 45.8 bits (107), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 45/172 (26%), Positives = 78/172 (45%), Gaps = 35/172 (20%) Query: 9 LEMCSHFDA-DEIKRLGKRFKKLDLDNSGSLSVEEFMS--------------LPELQQNP 53 L M S + +E K L F+ +D + G L +E + LP+++ Sbjct: 333 LYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESE- 391 Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQ-----KLRFAFRIYDMDKDGYIS 108 V ++ D D NG +D+ EF+ +V D++ KL AF+ +D D +G IS Sbjct: 392 -VDAILGAADFDRNGYIDYSEFV------TVAMDRKSLLSKDKLESAFQKFDQDGNGKIS 444 Query: 109 NGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 EL V + ++L+ ++++ D + DG + FEEFC ++ L Sbjct: 445 VDELASVFGL---DHLESKTWKEMIS----GIDSNNDGDVDFEEFCKMIQKL 489 Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 22/170 (12%) Query: 4 EASYPLEMCSHFDAD-EIKRLGKRFKKL-DLDNSGSLSVEEFMSLP-ELQQNPLVQRVID 60 E + EMCS ++ E+ L + + NS L+ + + +L + + D Sbjct: 291 EHPWIKEMCSKKESGIELPSLANAIENMRKFQNSQKLAQAALLYMASKLTSQEETKELTD 350 Query: 61 IF---DTDGNGEVDFKEFIEGVSQFSVKGDK---------EQKLRFAFRIYDMDKDGYIS 108 IF D +G+G++D +E I+G S+ S G++ E ++ D D++GYI Sbjct: 351 IFRHIDKNGDGQLDRQELIDGYSKLS--GEEVAVFDLPQIESEVDAILGAADFDRNGYID 408 Query: 109 NGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 E F + M + L +L+ K D+DG+G+IS +E +V G Sbjct: 409 YSE-FVTVAMDRKSLLSKDKLESAFQKF----DQDGNGKISVDELASVFG 453 >3L19-A nrPDB Length = 214 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 46/172 (26%), Positives = 78/172 (45%), Gaps = 35/172 (20%) Query: 9 LEMCSHFDA-DEIKRLGKRFKKLDLDNSGSLSVEEFMS--------------LPELQQNP 53 L M S + +E K L F+ +D + G L +E + LP+++ Sbjct: 50 LYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESE- 108 Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQ-----KLRFAFRIYDMDKDGYIS 108 V ++ D D NG +D+ EF+ +V D++ KL AF+ +D D +G IS Sbjct: 109 -VDAILGAADFDRNGYIDYSEFV------TVAMDRKSLLSKDKLESAFQKFDQDGNGKIS 161 Query: 109 NGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 EL V + ++L+ +++ I D + DG + FEEFC ++ L Sbjct: 162 VDELASVFGL---DHLESKTWKEM----ISGIDSNNDGDVDFEEFCKMIQKL 206 >5JOL-A nrPDB Length = 82 Score = 45.4 bits (106), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Query: 79 VSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII 138 +++ SV ++ +LR AF D D +GYIS EL + K L ++++I + + Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAAC-LPLPGYRVREITENLMA 59 Query: 139 NADKDGDGRISFEEFCAVVGGL 160 D D DGRISF+EF + GL Sbjct: 60 TGDLDQDGRISFDEFIKIFHGL 81 >5JN2-A nrPDB Length = 525 Score = 45.1 bits (105), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 44/156 (28%), Positives = 72/156 (46%), Gaps = 33/156 (21%) Query: 18 DEIKRLGKRFKKLDLDNSGSL-------SVEEFMSLPELQQNPL--------VQRVIDIF 62 DE K L F K+D + G L +E M + + L V +V+D Sbjct: 373 DETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAV 432 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKE-----QKLRFAFRIYDMDKDGYISNGELFQVLK 117 D D NG +++ EF+ +V D++ ++L AFR++D D G IS+ EL + Sbjct: 433 DFDKNGYIEYSEFV------TVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIF- 485 Query: 118 MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 G + D++ + V + DK+ DG + F+EF Sbjct: 486 ---GVSDVDSETWKSV---LSEVDKNNDGEVDFDEF 515 Score = 32.0 bits (71), Expect = 0.14, Method: Compositional matrix adjust. Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 31/156 (19%) Query: 32 LDNSGSLSVEEFMSLPELQQNPLV------------QRVIDIF---DTDGNGEVDFKEFI 76 LDN+ L++ +F +L Q L+ + + IF D +G+G++D E I Sbjct: 341 LDNA-ILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELI 399 Query: 77 EGVSQF-SVKGDK---------EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 EG + +KG E ++ D DK+GYI E + V + K Sbjct: 400 EGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEF-----VTVAMDRKT 454 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 ++ +++ D D G+IS E + G D+ Sbjct: 455 LLSRERLERAFRMFDSDNSGKISSTELATIFGVSDV 490 >4RGJ-A nrPDB Length = 520 Score = 45.1 bits (105), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 44/157 (28%), Positives = 74/157 (47%), Gaps = 35/157 (22%) Query: 18 DEIKRLGKRFKKLDLDNSGSL-------SVEEFMSLPELQQNPL--------VQRVIDIF 62 DE K L K FKK+D + G L +E + L + L V ++++ Sbjct: 368 DETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSI 427 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKE-----QKLRFAFRIYDMDKDGYISNGELFQVLK 117 D D NG +++ EF+ +V D++ ++L AF+++D D G IS EL Q+ Sbjct: 428 DLDQNGYIEYSEFL------TVSIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQLFG 481 Query: 118 MM-VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 + V + T L+++ D++ DG I F+EF Sbjct: 482 LSDVSSECWKTVLKEV--------DQNNDGEIDFKEF 510 Score = 33.1 bits (74), Expect = 0.067, Method: Compositional matrix adjust. Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 21/130 (16%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQF-SVKGDKEQKLRFAFRIY----- 99 L + + + ++ D +G+G++D E I G + +KG+ L A Y Sbjct: 364 LTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQI 423 Query: 100 ----DMDKDGYISNGELFQV---LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 D+D++GYI E V K+++ + ++K DKDG G+IS E Sbjct: 424 LNSIDLDQNGYIEYSEFLTVSIDRKLLLST--------ERLEKAFKLFDKDGSGKISANE 475 Query: 153 FCAVVGGLDI 162 + G D+ Sbjct: 476 LAQLFGLSDV 485 >3IFK-A nrPDB Length = 90 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 4/84 (4%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I + F D D G+++ +E + + L QNP +Q +I+ D DGNG +DF Sbjct: 7 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 66 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFR 97 EF+ +++ D E+++R AFR Sbjct: 67 EFLTMMARKMKDTDSEEEIREAFR 90 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF ++D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F EF Sbjct: 15 AFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQDMINE----VDADGNGTIDFPEFL 69 Query: 155 AVVG 158 ++ Sbjct: 70 TMMA 73 >5JOJ-A nrPDB Length = 97 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Query: 79 VSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII 138 +++ SV ++ +LR AF D D +GYIS EL + K L ++++I + + Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAAC-LPLPGYRVREITENLMA 59 Query: 139 NADKDGDGRISFEEFCAVVGGL 160 D D DGRISF+EF + GL Sbjct: 60 TGDLDQDGRISFDEFIKIFHGL 81 >1JC2-A nrPDB Length = 76 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 25/77 (32%), Positives = 48/77 (62%), Gaps = 5/77 (6%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 KG E++L FRI+D + DG+I EL ++L+ G ++ +++ ++ + ++DK+ Sbjct: 4 AKGKSEEELANCFRIFDKNADGFIDIEELGEILR-ATGEHV----IEEDIEDLMKDSDKN 58 Query: 144 GDGRISFEEFCAVVGGL 160 DGRI F+EF ++ G+ Sbjct: 59 NDGRIDFDEFLKMMEGV 75 >5ZGM-A nrPDB Length = 110 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 9/93 (9%) Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV--GNNLK 125 G D+K F + V +KG E +++ F I D D+ G+I EL VLK G +L Sbjct: 23 GTFDYKRFFQLVG---LKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLS 79 Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 DT+ + + + D D DG+I +EF +V Sbjct: 80 DTETKAL----LAAGDSDHDGKIGADEFAKMVA 108 >3FWC-A nrPDB Length = 161 Score = 43.1 bits (100), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 38/135 (28%), Positives = 68/135 (50%), Gaps = 9/135 (6%) Query: 27 FKKLDLDNSGSLSVEEFMSLPELQQNPLVQR----VIDIFDTDGNGEVDFKEFIEGVSQF 82 F D++N G L E + L +R +ID +D++G + + +F + + Sbjct: 29 FSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEK 88 Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 +K D +++ AF+++D D G IS L +V K + G L D +L+ ++++ D Sbjct: 89 ILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKEL-GETLTDEELRAMIEEF----DL 143 Query: 143 DGDGRISFEEFCAVV 157 DGDG I+ EF A+ Sbjct: 144 DGDGEINENEFIAIC 158 >2B1U-A nrPDB Length = 71 Score = 42.7 bits (99), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 5/67 (7%) Query: 92 LRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFE 151 L+ AFR +D D DG+I+ EL + + + G L Q+ +D I AD D DGR+++E Sbjct: 8 LQVAFRAFDQDGDGHITVDELRRAMAGL-GQPLP----QEELDAMIREADVDQDGRVNYE 62 Query: 152 EFCAVVG 158 EF ++ Sbjct: 63 EFARMLA 69 Score = 28.9 bits (63), Expect = 1.1, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 4/59 (6%) Query: 27 FKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF----DTDGNGEVDFKEFIEGVSQ 81 F+ D D G ++V+E PL Q +D D D +G V+++EF ++Q Sbjct: 12 FRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARMLAQ 70 >5H7D-E nrPDB Length = 120 Score = 42.7 bits (99), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 5/69 (7%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 Q + AF ++D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I Sbjct: 56 QAFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQDMINEV----DADGNGTID 110 Query: 150 FEEFCAVVG 158 F EF ++ Sbjct: 111 FPEFLTMMA 119 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 4/63 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I+ + F D D G+++ +E + + L QNP +Q +I+ D DGNG +DF Sbjct: 53 NQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 112 Query: 74 EFI 76 EF+ Sbjct: 113 EFL 115 >3KHE-A nrPDB Length = 191 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 41/160 (25%), Positives = 72/160 (45%), Gaps = 33/160 (20%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS---------------LPELQQNPLVQRVIDIF 62 +E K L + F++LD + G L +E + L Q V ++ Sbjct: 37 EETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSV 96 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKE-----QKLRFAFRIYDMDKDGYISNGELFQVLK 117 D D NG +++ EF+ +V DK+ ++L AF+ +D D G I+N EL ++ Sbjct: 97 DFDRNGYIEYSEFV------TVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFG 150 Query: 118 MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + + D Q++ + DK+ DG + FEEF ++ Sbjct: 151 V---TEVDDETWHQVLQE----CDKNNDGEVDFEEFVEMM 183 Score = 36.2 bits (82), Expect = 0.007, Method: Compositional matrix adjust. Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 21/126 (16%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQF-SVKGDK---------EQKLRFA 95 L L++ + ++ D +G+G++D KE IEG + KGD E ++ Sbjct: 33 LTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHI 92 Query: 96 FRIYDMDKDGYISNGELFQVL---KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 + D D++GYI E V ++++ QQ D DG G+I+ EE Sbjct: 93 LQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQF--------DSDGSGKITNEE 144 Query: 153 FCAVVG 158 + G Sbjct: 145 LGRLFG 150 >3HZT-A nrPDB Length = 467 Score = 42.0 bits (97), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 41/156 (26%), Positives = 70/156 (44%), Gaps = 33/156 (21%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS---------------LPELQQNPLVQRVIDIF 62 +E K L + F++LD + G L +E + L Q V ++ Sbjct: 311 EETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSV 370 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKE-----QKLRFAFRIYDMDKDGYISNGELFQVLK 117 D D NG +++ EF+ +V DK+ ++L AF+ +D D G I+N EL ++ Sbjct: 371 DFDRNGYIEYSEFV------TVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFG 424 Query: 118 MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 + + D Q++ + DK+ DG + FEEF Sbjct: 425 V---TEVDDETWHQVLQE----CDKNNDGEVDFEEF 453 Score = 36.6 bits (83), Expect = 0.005, Method: Compositional matrix adjust. Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 21/130 (16%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQF-SVKGDK---------EQKLRFA 95 L L++ + ++ D +G+G++D KE IEG + KGD E ++ Sbjct: 307 LTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHI 366 Query: 96 FRIYDMDKDGYISNGELFQVL---KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 + D D++GYI E V ++++ QQ D DG G+I+ EE Sbjct: 367 LQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQF--------DSDGSGKITNEE 418 Query: 153 FCAVVGGLDI 162 + G ++ Sbjct: 419 LGRLFGVTEV 428 Score = 32.7 bits (73), Expect = 0.075, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 2/59 (3%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQ--NPLVQRVIDIFDTDGNGEVDFKEFIE 77 +RL F++ D D SG ++ EE L + + + +V+ D + +GEVDF+EF+E Sbjct: 397 ERLLAAFQQFDSDGSGKITNEELGRLFGVTEVDDETWHQVLQECDKNNDGEVDFEEFVE 455 >4WPX-A nrPDB Length = 177 Score = 42.0 bits (97), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 42/167 (25%), Positives = 78/167 (46%), Gaps = 23/167 (13%) Query: 8 PLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEF--------MSLPELQQNPLV---- 55 P E + ++ R+ + F+ D + G LS EEF LP+ Q ++ Sbjct: 13 PREDYNKLSDEQKTRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHG 72 Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSV-----KGDKEQKLRFAFRIYDMDKDGYISNG 110 QR + + D +++F +Q + D +LR AFR++D+D G I+ Sbjct: 73 QRPAN-WPHDQECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITED 131 Query: 111 ELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 +L +V + VGNN+ D +Q ++++ D +G G + +EF ++ Sbjct: 132 DLRKVCQ-QVGNNIPDADIQAMIEEF----DSNGKGGVDEDEFLRLM 173 >1RTP-1 nrPDB Length = 109 Score = 42.0 bits (97), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 36/115 (31%), Positives = 57/115 (49%), Gaps = 9/115 (7%) Query: 45 SLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKD 104 S+ +L +++ I F + D K+F + V D +K+ F I D DK Sbjct: 1 SMTDLLSAEDIKKAIGAFTAADS--FDHKKFFQMVGLKKKSADDVKKV---FHILDKDKS 55 Query: 105 GYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA-DKDGDGRISFEEFCAVVG 158 G+I EL +LK ++ +D ++ KT++ A DKDGDG+I EEF +V Sbjct: 56 GFIEEDELGSILKGF-SSDARDLSAKET--KTLMAAGDKDGDGKIGVEEFSTLVA 107 >2L50-A nrPDB Length = 102 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 20/54 (37%), Positives = 33/54 (61%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 IS ++L+ + + L DT ++ DK I N D + DGRISF+E+ ++GG+ Sbjct: 32 ISKSSFREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGI 85 >1G33-A nrPDB Length = 73 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/64 (40%), Positives = 37/64 (57%), Gaps = 4/64 (6%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA-DKDGDGRISFEEFC 154 F I D DK G+I EL +LK ++ +D ++ KT++ A DKDGDG+I EEF Sbjct: 11 FHILDKDKSGFIEEDELGSILKGF-SSDARDLSAKET--KTLMAAGDKDGDGKIGVEEFS 67 Query: 155 AVVG 158 +V Sbjct: 68 TLVA 71 >4N5X-A nrPDB Length = 199 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 37/151 (24%), Positives = 71/151 (47%), Gaps = 15/151 (9%) Query: 7 YPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ----RVIDIF 62 + L + DA++ R F+ LD + G + + E PL Q ++ Sbjct: 8 FVLPTAASQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTG 67 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 D + +G++DF+EF++ + D E+K++ AF+ D + DG I E+ Q L+ + G Sbjct: 68 DVNKDGKLDFEEFMKYLK------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTL-GL 120 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 + + Q + I+ + D DG + + E+ Sbjct: 121 TISEQQAELILQ----SIDVDGTMTVDWNEW 147 >1OZS-A nrPDB Length = 73 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 46/78 (58%), Gaps = 5/78 (6%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 +KG E++L FR++D + DGYI EL +++ G + + +++++ + DK+ Sbjct: 1 MKGKSEEELSDLFRMFDKNADGYIDLEEL-KIMLQATGETITEDDIEELMK----DGDKN 55 Query: 144 GDGRISFEEFCAVVGGLD 161 DGRI ++EF + G++ Sbjct: 56 NDGRIDYDEFLEFMKGVE 73 >2I08-A nrPDB Length = 78 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF +YD D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F EF Sbjct: 15 AFSLYDKDGDGTITTKELGTVMRSL-GLNPTEAELQDMINE----VDADGNGTIDFPEFL 69 Query: 155 AVVG 158 ++ Sbjct: 70 TMMA 73 Score = 33.9 bits (76), Expect = 0.037, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 4/63 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I + F D D G+++ +E + + L NP +Q +I+ D DGNG +DF Sbjct: 7 EQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFP 66 Query: 74 EFI 76 EF+ Sbjct: 67 EFL 69 >5PAL-A nrPDB Length = 109 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 9/93 (9%) Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV--GNNLK 125 G D+K F V +KG + +++ F I D D+ G+I EL VLK G +L Sbjct: 22 GTFDYKRFFHLVG---LKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLN 78 Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 DT+ + + + D D DG+I +EF +V Sbjct: 79 DTETKAL----LAAGDSDHDGKIGADEFAKMVA 107 >5COC-A nrPDB Length = 130 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 15/122 (12%) Query: 42 EFMSLPEL---QQNPLVQRVIDIFDTDGN--GEVDFKEFIEGVSQFSVKGDKEQKLRFAF 96 E + LP L Q+N +Q + D N E + ++ + KE AF Sbjct: 15 EILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKCLNDAQAAAEECIAEFKE-----AF 69 Query: 97 RIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAV 156 ++D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F EF + Sbjct: 70 SLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQDMINEV----DADGNGTIDFPEFLTM 124 Query: 157 VG 158 + Sbjct: 125 MA 126 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 11/78 (14%) Query: 3 NEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRV 58 N+A E C I + F D D G+++ +E + + L QNP +Q + Sbjct: 52 NDAQAAAEEC-------IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM 104 Query: 59 IDIFDTDGNGEVDFKEFI 76 I+ D DGNG +DF EF+ Sbjct: 105 INEVDADGNGTIDFPEFL 122 >4Q57-A nrPDB Length = 65 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF ++D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F EF Sbjct: 7 AFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQDMINE----VDADGNGTIDFPEFL 61 Query: 155 AVVG 158 ++ Sbjct: 62 TMMA 65 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 4/61 (6%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFKEF 75 I + F D D G+++ +E + + L QNP +Q +I+ D DGNG +DF EF Sbjct: 1 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 60 Query: 76 I 76 + Sbjct: 61 L 61 >4ZCV-A nrPDB Length = 165 Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 36/142 (25%), Positives = 68/142 (47%), Gaps = 15/142 (10%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ----RVIDIFDTDGNGEVD 71 DA++ R F+ LD + G + + E PL Q ++ D + +G++D Sbjct: 8 DAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLD 67 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 F+EF++ + D E+K++ AF+ D + DG I E+ Q L+ + G + + Q + Sbjct: 68 FEEFMKYLK------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTL-GLTISEQQAEL 120 Query: 132 IVDKTIINADKDGDGRISFEEF 153 I+ + D DG + + E+ Sbjct: 121 ILQ----SIDVDGTMTVDWNEW 138 >3SIA-A nrPDB Length = 220 Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 6/78 (7%) Query: 3 NEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM--SLPE-LQQNP-LVQRV 58 N +PL + D+ R+ + F +D D SG+L + E M P ++ +P R+ Sbjct: 35 NTWWFPL--LNTIPLDQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRLSPQTALRM 92 Query: 59 IDIFDTDGNGEVDFKEFI 76 + IFDTD NG + F EF+ Sbjct: 93 MRIFDTDFNGHISFYEFM 110 Score = 32.0 bits (71), Expect = 0.14, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 6/86 (6%) Query: 39 SVEEFMSLPELQQNPLVQ--RVIDIF---DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLR 93 SV P L PL Q R+ F D D +G ++ E + G ++ + LR Sbjct: 32 SVRNTWWFPLLNTIPLDQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRLSPQTALR 91 Query: 94 FAFRIYDMDKDGYISNGELFQVLKMM 119 RI+D D +G+IS E + K M Sbjct: 92 MM-RIFDTDFNGHISFYEFMAMYKFM 116 >5E37-A nrPDB Length = 356 Score = 40.0 bits (92), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 39/148 (26%), Positives = 73/148 (49%), Gaps = 18/148 (12%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPE---------LQQNPL----VQRVIDIFDTD 65 +++ L +RFK D+D +G + EE +L E + Q+ L ++R ++ +D + Sbjct: 27 KMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVN 86 Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 +G + F+EF + + + + AF+ D +G I EL ++ + GN + Sbjct: 87 KDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASL-GNPV- 144 Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEF 153 L+++VD + DKD G+I F EF Sbjct: 145 --SLEKLVDLMQMY-DKDDSGQIEFPEF 169 Score = 32.3 bits (72), Expect = 0.098, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 12/78 (15%) Query: 88 KEQKLRFAFRIYDMDKDGYISNGELFQVLK--------MMVGNNLKDTQLQQIVDKTIIN 139 K ++L F++ D+D +G+I EL +L+ MM + L + +L++ +++ +N Sbjct: 27 KMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVN 86 Query: 140 ADKDGDGRISFEEFCAVV 157 D G ISFEEF ++ Sbjct: 87 KD----GVISFEEFKQII 100 Score = 29.3 bits (64), Expect = 0.90, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 32/54 (59%), Gaps = 4/54 (7%) Query: 27 FKKLDLDNSGSLSVEEFMSLPELQQNPL-VQRVIDI---FDTDGNGEVDFKEFI 76 FK +D +G++ E L NP+ +++++D+ +D D +G+++F EF+ Sbjct: 117 FKAVDKSGNGTIGATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEFPEFL 170 >1TNP-A nrPDB Length = 90 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 38/67 (56%), Gaps = 5/67 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF ++D D G IS EL V++M+ G N +L I+++ D+DG G I F Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMRML-GQNPTKEELDAIIEEV----DEDGSGTIDF 75 Query: 151 EEFCAVV 157 EEF ++ Sbjct: 76 EEFLVMM 82 Score = 33.1 bits (74), Expect = 0.064, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 4/61 (6%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPE-LQQNPL---VQRVIDIFDTDGNGEVDFKEF 75 I F D D G +S +E ++ L QNP + +I+ D DG+G +DF+EF Sbjct: 19 IAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEF 78 Query: 76 I 76 + Sbjct: 79 L 79 >1TRF-A nrPDB Length = 76 Score = 39.7 bits (91), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 38/67 (56%), Gaps = 5/67 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF ++D D G IS EL V++M+ G N +L I+++ D+DG G I F Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMRML-GQNPTKEELDAIIEEV----DEDGSGTIDF 64 Query: 151 EEFCAVV 157 EEF ++ Sbjct: 65 EEFLVMM 71 Score = 32.7 bits (73), Expect = 0.073, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 12/71 (16%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPE-LQQNPL---VQRVIDIFDTD 65 EM + F A F D D G +S +E ++ L QNP + +I+ D D Sbjct: 6 EMIAEFKA--------AFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDED 57 Query: 66 GNGEVDFKEFI 76 G+G +DF+EF+ Sbjct: 58 GSGTIDFEEFL 68 >2PMY-A nrPDB Length = 91 Score = 39.7 bits (91), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-PELQQNPL-VQRVIDIFDTDGNGEVDFK 73 D +E+ RL F D + SG L EEF +L EL+ P + V D D +G + F+ Sbjct: 22 DGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDGAITFQ 81 Query: 74 EFIEG 78 EF G Sbjct: 82 EFARG 86 >2RO8-A nrPDB Length = 79 Score = 39.7 bits (91), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF ++D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F EF Sbjct: 15 AFSLFDKDGDGCITTKELGTVMRSL-GQNPTEAELQDMINE----VDADGNGTIDFPEFL 69 Query: 155 AVVG 158 ++ Sbjct: 70 NLMA 73 Score = 36.2 bits (82), Expect = 0.007, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 4/63 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I + F D D G ++ +E + + L QNP +Q +I+ D DGNG +DF Sbjct: 7 EQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 66 Query: 74 EFI 76 EF+ Sbjct: 67 EFL 69 >1GGW-A nrPDB Length = 140 Score = 39.7 bits (91), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 27/110 (24%), Positives = 60/110 (54%), Gaps = 11/110 (10%) Query: 51 QNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQ---FSVKGDKEQKLRFAFRIYDMDKDGYI 107 QNP + + +I ++ EVD ++F++ +++ F + GD E+ ++ F+++D D G I Sbjct: 36 QNPTLAEITEI-ESTLPAEVDMEQFLQVLNRPNGFDMPGDPEEFVK-GFQVFDKDATGMI 93 Query: 108 SNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 GEL VL + G L + ++ +++ + DG +++ +F ++ Sbjct: 94 GVGELRYVLTSL-GEKLSNEEMDELLKGVPVK-----DGMVNYHDFVQMI 137 >6IIE-A nrPDB Length = 93 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 4/73 (5%) Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQ-VLKMMVGNNLKD---TQLQQIVDKTIINAD 141 G E KL F F++YD D++G + + E+ + +L+MM D ++L+ I+ + + D Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEID 64 Query: 142 KDGDGRISFEEFC 154 DG G +S E+ Sbjct: 65 YDGSGSVSQAEWV 77 >2N7L-C nrPDB Length = 141 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/73 (36%), Positives = 45/73 (61%), Gaps = 8/73 (10%) Query: 88 KEQKLRF--AFRIYDM-DKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDG 144 +EQK F AF I+ + +DG IS EL +V++M+ G N +LQ+++D+ D+DG Sbjct: 29 EEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRML-GQNPTPEELQEMIDEV----DEDG 83 Query: 145 DGRISFEEFCAVV 157 G + F+EF ++ Sbjct: 84 SGTVDFDEFLVMM 96 Score = 32.3 bits (72), Expect = 0.10, Method: Compositional matrix adjust. Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 4/45 (8%) Query: 36 GSLSVEEFMSLPE-LQQNPL---VQRVIDIFDTDGNGEVDFKEFI 76 GS+S +E + L QNP +Q +ID D DG+G VDF EF+ Sbjct: 49 GSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFL 93 >5VLN-A nrPDB Length = 120 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/73 (36%), Positives = 45/73 (61%), Gaps = 8/73 (10%) Query: 88 KEQKLRF--AFRIYDM-DKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDG 144 +EQK F AF I+ + +DG IS EL +V++M+ G N +LQ+++D+ D+DG Sbjct: 14 EEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRML-GQNPTPEELQEMIDEV----DEDG 68 Query: 145 DGRISFEEFCAVV 157 G + F+EF ++ Sbjct: 69 SGTVDFDEFLVMM 81 Score = 32.3 bits (72), Expect = 0.091, Method: Compositional matrix adjust. Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 4/45 (8%) Query: 36 GSLSVEEFMSLPE-LQQNPL---VQRVIDIFDTDGNGEVDFKEFI 76 GS+S +E + L QNP +Q +ID D DG+G VDF EF+ Sbjct: 34 GSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFL 78 >2M97-A nrPDB Length = 69 Score = 38.5 bits (88), Expect = 0.001, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 40/69 (57%), Gaps = 5/69 (7%) Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRI 148 E++L FRI+D D +G+I E +++ + G L D + VD+ ++D D +GRI Sbjct: 2 EEELSECFRIFDKDGNGFIDREEFGDIIR-LTGEQLTD----EDVDEIFGDSDTDKNGRI 56 Query: 149 SFEEFCAVV 157 F+EF ++ Sbjct: 57 DFDEFLKMM 65 Score = 31.6 bits (70), Expect = 0.17, Method: Compositional matrix adjust. Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 4/60 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID-IF---DTDGNGEVDFKEFI 76 + L + F+ D D +G + EEF + L L +D IF DTD NG +DF EF+ Sbjct: 3 EELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFL 62 >5XND-A nrPDB Length = 114 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 33/118 (27%), Positives = 52/118 (44%), Gaps = 11/118 (9%) Query: 44 MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDK 103 M+ + ++ V +D G D K+F + + G +++ AF I D DK Sbjct: 6 MAFASVLKDAEVTAALD--GCKAAGSFDHKKFFKACG---LSGKSTDEVKKAFAIIDQDK 60 Query: 104 DGYISNGELFQVLKMMVGN-NLKDTQLQQIVDKTIINA-DKDGDGRISFEEFCAVVGG 159 G+I EL K+ + N L K + A D DGDG+I +EF A++ G Sbjct: 61 SGFIEEEEL----KLFLQNFKAGARALSDAETKAFLKAGDSDGDGKIGIDEFAAMIKG 114 >3TZ1-A nrPDB Length = 74 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 39/65 (60%), Gaps = 5/65 (7%) Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRI 148 E++L+ AFR+ D +K G I L +LK + G+ L + +++ ++ +T D DG G + Sbjct: 6 ERELKEAFRVLDKEKKGVIKVDVLRWILKSL-GDELTEDEIENMIAET----DTDGSGTV 60 Query: 149 SFEEF 153 +EEF Sbjct: 61 DYEEF 65 Score = 27.3 bits (59), Expect = 3.6, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 7/65 (10%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGNGEV 70 D DE + L + F+ LD + G + V+ + EL ++ ++ +I DTDG+G V Sbjct: 3 DLDE-RELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDE-IENMIAETDTDGSGTV 60 Query: 71 DFKEF 75 D++EF Sbjct: 61 DYEEF 65 >2BL0-C nrPDB Length = 142 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 6/95 (6%) Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 D GNG++ F EF+ + + + E LR AFR +D + GYI L L + +G+ Sbjct: 52 DATGNGKIQFPEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDAL-LNLGD 110 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 LK + + + I +K G+I ++ F + Sbjct: 111 RLKPHEFAEFLG--ITETEK---GQIRYDNFINTM 140 >3E3R-A nrPDB Length = 204 Score = 37.7 bits (86), Expect = 0.002, Method: Compositional matrix adjust. Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 16/153 (10%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGN 67 C A I+ L + F++LD D S SL +EF L + + V +D +G+ Sbjct: 28 CLSRGASGIQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGS 87 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL------KMMVG 121 G +D +EF+ + + + +E + AF D DG ++ +L V K+ G Sbjct: 88 GTLDLEEFLRAL-RPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSG 146 Query: 122 NNLKDTQLQQIVDKTIINAD-KDGDGRISFEEF 153 +D L++ +D N D + DG+++ EF Sbjct: 147 EWTEDEVLRRFLD----NFDSSEKDGQVTLAEF 175 >4GJF-A nrPDB Length = 89 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 27/69 (39%), Positives = 42/69 (60%), Gaps = 8/69 (11%) Query: 88 KEQKLRF--AFRIY-DMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDG 144 +EQK F AF I+ +DG IS EL +V++M+ G N +LQ+++D+ D+DG Sbjct: 14 EEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRML-GQNPTPEELQEMIDEV----DEDG 68 Query: 145 DGRISFEEF 153 G + F+EF Sbjct: 69 SGTVDFDEF 77 Score = 30.4 bits (67), Expect = 0.42, Method: Compositional matrix adjust. Identities = 16/31 (51%), Positives = 20/31 (64%), Gaps = 3/31 (9%) Query: 49 LQQNPL---VQRVIDIFDTDGNGEVDFKEFI 76 L QNP +Q +ID D DG+G VDF EF+ Sbjct: 48 LGQNPTPEELQEMIDEVDEDGSGTVDFDEFL 78 >5VE9-A nrPDB Length = 91 Score = 37.0 bits (84), Expect = 0.004, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 4/57 (7%) Query: 27 FKKLDLDNSGSLSVEEFMSLPELQQNPLVQ----RVIDIFDTDGNGEVDFKEFIEGV 79 F+++D D G ++ +EF+ + P + V DIFD DG+G +D+ EF+ + Sbjct: 33 FRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAAL 89 Score = 30.4 bits (67), Expect = 0.35, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 5/62 (8%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 FR D D+DG I+ E + ++ + T+L+ I D+DGDG I + EF A Sbjct: 33 FRRIDKDQDGKITRQEF---IDGILASKFPTTKLEMTAVADIF--DRDGDGYIDYYEFVA 87 Query: 156 VV 157 + Sbjct: 88 AL 89 Score = 28.9 bits (63), Expect = 1.0, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 56 QRVIDIF---DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 RV+D F D D +G++ +EFI+G+ K + A I+D D DGYI E Sbjct: 27 SRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVA-DIFDRDGDGYIDYYEF 85 Query: 113 FQVL 116 L Sbjct: 86 VAAL 89 >3PAT-A nrPDB Length = 110 Score = 37.0 bits (84), Expect = 0.004, Method: Compositional matrix adjust. Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 6/64 (9%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMV--GNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 F+ D D G+I EL VLK G +L D + + + ADKDGDG+I +EF Sbjct: 48 FKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLK----AADKDGDGKIGIDEF 103 Query: 154 CAVV 157 +V Sbjct: 104 ETLV 107 >5MWC-D nrPDB Length = 311 Score = 37.0 bits (84), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRI 148 E++L FR +D D DG+I E +++ + G L D +I ++D D +GRI Sbjct: 150 EEELSECFRTFDKDGDGFIDREEFGGIIR-LTGEQLTDEDPDEIFG----DSDTDKNGRI 204 Query: 149 SFEEFCAVV 157 F+EF +V Sbjct: 205 DFDEFLKMV 213 Score = 30.0 bits (66), Expect = 0.50, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 4/63 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID-IF---DTDGNGEVDFKEFI 76 + L + F+ D D G + EEF + L L D IF DTD NG +DF EF+ Sbjct: 151 EELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFL 210 Query: 77 EGV 79 + V Sbjct: 211 KMV 213 >2LVK-A nrPDB Length = 77 Score = 37.0 bits (84), Expect = 0.004, Method: Compositional matrix adjust. Identities = 24/63 (38%), Positives = 37/63 (58%), Gaps = 6/63 (9%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL--VQRVIDIFDTDGNGEVDFK 73 AD+++R+ FK+ D + G +S+ E +L L VQR++ DTDG+G +DF Sbjct: 1 ADDMERI---FKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFN 57 Query: 74 EFI 76 EFI Sbjct: 58 EFI 60 Score = 30.8 bits (68), Expect = 0.30, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 9/68 (13%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE--- 152 F+ +D + DG IS EL L+ + + + Q + + D DGDG I F E Sbjct: 8 FKRFDTNGDGKISLSELTDALRTLGSTSADEVQ------RMMAEIDTDGDGFIDFNEFIS 61 Query: 153 FCAVVGGL 160 FC GL Sbjct: 62 FCNANPGL 69 Score = 26.9 bits (58), Expect = 4.8, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 4/59 (6%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQF-SVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 ++R+ FDT+G+G++ E + + S D+ Q++ D D DG+I E Sbjct: 4 MERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRM---MAEIDTDGDGFIDFNEF 59 >2AMI-A nrPDB Length = 96 Score = 36.6 bits (83), Expect = 0.005, Method: Compositional matrix adjust. Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 +++Q++R AF ++D D G I EL +V +G K +++ K I DKDG G Sbjct: 27 EQKQEIREAFDLFDTDGSGTIDAKEL-KVAMRALGFEPKKEEIK----KMISEIDKDGSG 81 Query: 147 RISFEEFCAVV 157 I FEEF ++ Sbjct: 82 TIDFEEFLTMM 92 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%) Query: 50 QQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDG 105 +Q ++ D+FDTDG+G +D KE + + KE+ + I ++DKDG Sbjct: 27 EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKM---ISEIDKDG 79 Score = 30.4 bits (67), Expect = 0.45, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 4/54 (7%) Query: 27 FKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEVDFKEFI 76 F D D SG++ +E +++ L P ++++I D DG+G +DF+EF+ Sbjct: 36 FDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFL 89 >1RK9-A nrPDB Length = 110 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 9/116 (7%) Query: 44 MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDK 103 MS+ +L +++ + F D K+F + V D +K+ F + D DK Sbjct: 1 MSMTDLLNAEDIKKAVGAFSA--TDSFDHKKFFQMVGLKKKSADDVKKV---FHMLDKDK 55 Query: 104 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA-DKDGDGRISFEEFCAVVG 158 G+I EL +LK G + L K ++ A DKDGDG+I +EF +V Sbjct: 56 SGFIEEDELGFILK---GFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVA 108 >5OTJ-D nrPDB Length = 110 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 24/63 (38%), Positives = 37/63 (58%), Gaps = 6/63 (9%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL--VQRVIDIFDTDGNGEVDFK 73 AD+++R+ FK+ D + G +S+ E +L L VQR++ DTDG+G +DF Sbjct: 2 ADDMERI---FKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFN 58 Query: 74 EFI 76 EFI Sbjct: 59 EFI 61 Score = 31.2 bits (69), Expect = 0.25, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 9/68 (13%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE--- 152 F+ +D + DG IS EL L+ + + + Q + + D DGDG I F E Sbjct: 9 FKRFDTNGDGKISLSELTDALRTLGSTSADEVQ------RMMAEIDTDGDGFIDFNEFIS 62 Query: 153 FCAVVGGL 160 FC GL Sbjct: 63 FCNANPGL 70 Score = 27.7 bits (60), Expect = 2.6, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 28/54 (51%), Gaps = 4/54 (7%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQF-SVKGDKEQKLRFAFRIYDMDKDGYI 107 ++R+ FDT+G+G++ E + + S D+ Q++ D D DG+I Sbjct: 5 MERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEI---DTDGDGFI 55 >5CPV-A nrPDB Length = 109 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 6/65 (9%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQ-LQQIVDKTIINA-DKDGDGRISFEE 152 AF I D DK G+I EL K+ + N D + L KT + A D DGDG+I +E Sbjct: 47 AFAIIDQDKSGFIEEDEL----KLFLQNFKADARALTDGETKTFLKAGDSDGDGKIGVDE 102 Query: 153 FCAVV 157 F A+V Sbjct: 103 FTALV 107 >5XOP-A nrPDB Length = 66 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 38/67 (56%), Gaps = 9/67 (13%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNN--LKDTQLQQIVDKTIINADKDGDGRISFEEF 153 F+ D++ DG +S ++ +K V +K+ QL Q++ K+I DKDGDG I FEEF Sbjct: 6 FKEIDVNGDGAVS----YEEVKAFVSKKRAIKNEQLLQLIFKSI---DKDGDGFIDFEEF 58 Query: 154 CAVVGGL 160 G + Sbjct: 59 AKFYGSI 65 Score = 33.5 bits (75), Expect = 0.053, Method: Compositional matrix adjust. Identities = 20/53 (37%), Positives = 33/53 (62%), Gaps = 4/53 (7%) Query: 27 FKKLDLDNSGSLSVEE---FMSLPELQQNP-LVQRVIDIFDTDGNGEVDFKEF 75 FK++D++ G++S EE F+S +N L+Q + D DG+G +DF+EF Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEF 58 >1OQP-A nrPDB Length = 77 Score = 35.8 bits (81), Expect = 0.008, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D +++ AFR++D D G I+ +L +V K + G NL + +LQ++ I AD++ D Sbjct: 6 DSREEILKAFRLFDDDNSGTITIKDLRRVAKEL-GENLTEEELQEM----IAEADRNDDN 60 Query: 147 RISFEEFCAVV 157 I +EF ++ Sbjct: 61 EIDEDEFIRIM 71 >2KSZ-A nrPDB Length = 76 Score = 35.8 bits (81), Expect = 0.009, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 42/73 (57%), Gaps = 7/73 (9%) Query: 88 KEQKLRF--AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 +EQ + F AF ++D D DG I+ EL V++ + N + +LQ ++ + D DG+ Sbjct: 6 EEQIVDFKEAFGLFDKDGDGCITVEELATVIRSL-DQNPTEEELQDMISEV----DADGN 60 Query: 146 GRISFEEFCAVVG 158 G I F+EF +++ Sbjct: 61 GTIEFDEFLSLMA 73 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 4/63 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I + F D D G ++VEE + + L QNP +Q +I D DGNG ++F Sbjct: 7 EQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFD 66 Query: 74 EFI 76 EF+ Sbjct: 67 EFL 69 Score = 26.9 bits (58), Expect = 4.2, Method: Compositional matrix adjust. Identities = 12/21 (57%), Positives = 14/21 (66%) Query: 141 DKDGDGRISFEEFCAVVGGLD 161 DKDGDG I+ EE V+ LD Sbjct: 20 DKDGDGCITVEELATVIRSLD 40 >2N8Y-A nrPDB Length = 153 Score = 35.4 bits (80), Expect = 0.012, Method: Compositional matrix adjust. Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 10/114 (8%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL---------PELQQNPLVQRVIDIFD 63 S +++ F D D+SG+L EEF + + Q R++ I D Sbjct: 2 SSISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVD 61 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 117 + G V F+ FI+ +S+ + D ++ +F+I DK+ YI+ EL + L Sbjct: 62 PNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITMDELRRELP 114 >1W7I-B nrPDB Length = 151 Score = 35.4 bits (80), Expect = 0.012, Method: Compositional matrix adjust. Identities = 34/148 (22%), Positives = 69/148 (46%), Gaps = 16/148 (10%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIFDTDGNGE---- 69 F+ D+++ + F+ D G + + + L QNP V+ + + E Sbjct: 4 FNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSR 63 Query: 70 -VDFKEFI---EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 VDF+ F+ + V++ +G E L FR++D + +G + EL VL + G + Sbjct: 64 RVDFETFLPMLQAVAKNRGQGTYEDYLE-GFRVFDKEGNGKVMGAELRHVLTTL-GEKMT 121 Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEF 153 + +++ T++ +D +G I++E F Sbjct: 122 EEEVE-----TVLAGHEDSNGCINYEAF 144 >5CSF-A nrPDB Length = 95 Score = 35.4 bits (80), Expect = 0.014, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 30/52 (57%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 + EL +++ + + L++ + Q++VDK + D DGDG F+EF A V Sbjct: 31 LKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVA 82 Score = 35.0 bits (79), Expect = 0.014, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 26/39 (66%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 L E+++ +V +V++ D DG+GE DF+EF+ V+ + Sbjct: 48 LEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTT 86 >1H4B-A nrPDB Length = 84 Score = 35.0 bits (79), Expect = 0.015, Method: Compositional matrix adjust. Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 7/68 (10%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 DK ++ R F+ +D + DG IS EL + LK + G+ D V + D DGDG Sbjct: 7 DKAERERI-FKRFDANGDGKISAAELGEALKTL-GSITPDE-----VKHMMAEIDTDGDG 59 Query: 147 RISFEEFC 154 ISF+EF Sbjct: 60 FISFQEFT 67 Score = 26.6 bits (57), Expect = 5.6, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 5/55 (9%) Query: 27 FKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 FK+ D + G +S E +L + + + + +I DTDG+G + F+EF + Sbjct: 15 FKRFDANGDGKISAAELGEALKTLGSITPDEVKHMMAEI-DTDGDGFISFQEFTD 68 >2M7M-A nrPDB Length = 66 Score = 35.0 bits (79), Expect = 0.016, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 4/53 (7%) Query: 27 FKKLDLDNSGSLSVEE---FMSLPELQQNP-LVQRVIDIFDTDGNGEVDFKEF 75 FK++D++ G++S EE F+S +N L+Q + D DGNGE+D EF Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEF 58 Score = 28.1 bits (61), Expect = 2.0, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 9/67 (13%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNN--LKDTQLQQIVDKTIINADKDGDGRISFEEF 153 F+ D++ DG +S ++ +K V +K+ QL Q++ K+I D DG+G I EF Sbjct: 6 FKEIDVNGDGAVS----YEEVKAFVSKKRAIKNEQLLQLIFKSI---DADGNGEIDQNEF 58 Query: 154 CAVVGGL 160 G + Sbjct: 59 AKFYGSI 65 >1Y1X-A nrPDB Length = 191 Score = 35.0 bits (79), Expect = 0.017, Method: Compositional matrix adjust. Identities = 31/138 (22%), Positives = 64/138 (46%), Gaps = 16/138 (11%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDFKEFI 76 + L + F+ +D D SG++SV E + P ++++ ++D + +GE+ F EF Sbjct: 27 QELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDKNHSGEITFDEF- 85 Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKT 136 + + F + +R FR D DG + + E+ L + G + + Q ++ K Sbjct: 86 KDLHHFIL------SMREGFRKRDSSGDGRLDSNEVRAAL-LSSGYQVSEQTFQALMRK- 137 Query: 137 IINADKDGDGRISFEEFC 154 D+ G + F+++ Sbjct: 138 ---FDRQRRGSLGFDDYV 152 >2K7B-A nrPDB Length = 76 Score = 35.0 bits (79), Expect = 0.018, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 44/76 (57%), Gaps = 5/76 (6%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 S++ ++ ++LR AFR +D DKDGYI+ +L ++ M G + +L ++ + +N Sbjct: 3 SLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTM-GYMPTEMELIELSQQINMNL-- 59 Query: 143 DGDGRISFEEFCAVVG 158 G + F++F ++G Sbjct: 60 --GGHVDFDDFVELMG 73 >1S6J-A nrPDB Length = 87 Score = 34.7 bits (78), Expect = 0.019, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 6/71 (8%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-----LPELQQNPLVQRVIDIFDTD 65 M +EI L + FK +D DNSG+++ +E EL ++ ++ ++D D D Sbjct: 13 MAERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESE-IKDLMDAADID 71 Query: 66 GNGEVDFKEFI 76 +G +D+ EFI Sbjct: 72 KSGTIDYGEFI 82 >1YX7-A nrPDB Length = 83 Score = 34.7 bits (78), Expect = 0.022, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Query: 92 LRFAFRIYDMDKDGYISNGELFQVLKMM-VGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 L AF+ D + DGY++ EL + + L ++++ K I ADK+ DG+IS Sbjct: 9 LEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGKISK 68 Query: 151 EEF 153 EEF Sbjct: 69 EEF 71 >1F55-A nrPDB Length = 77 Score = 34.3 bits (77), Expect = 0.024, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 38/64 (59%), Gaps = 5/64 (7%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF ++D D +G IS+ EL V++ + G + + ++ ++++ D DG+ +I F EF Sbjct: 15 AFALFDKDNNGSISSSELATVMRSL-GLSPSEAEVNDLMNEI----DVDGNHQIEFSEFL 69 Query: 155 AVVG 158 A++ Sbjct: 70 ALMS 73 Score = 33.5 bits (75), Expect = 0.045, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 4/74 (5%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIF---DTDGN 67 S+ ++I + F D DN+GS+S E + + L +P V D+ D DGN Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 60 Query: 68 GEVDFKEFIEGVSQ 81 +++F EF+ +S+ Sbjct: 61 HQIEFSEFLALMSR 74 >4PAL-A nrPDB Length = 108 Score = 34.3 bits (77), Expect = 0.029, Method: Compositional matrix adjust. Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 9/87 (10%) Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV--GNNLKDTQLQ 130 KEF V S D +K AF + D DK G+I EL L+ L D + + Sbjct: 27 KEFFAKVGLASKSLDDVKK---AFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETK 83 Query: 131 QIVDKTIINADKDGDGRISFEEFCAVV 157 + + DKDGDG I +EF A++ Sbjct: 84 AF----LADGDKDGDGMIGVDEFAAMI 106 >1C7W-A nrPDB Length = 81 Score = 33.9 bits (76), Expect = 0.032, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 4/74 (5%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 V+ D E+++ AF+++D + DG I E +++ + L D + V++ + AD+D Sbjct: 2 VRQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAE----VEEAMKEADED 57 Query: 144 GDGRISFEEFCAVV 157 G+G I EF ++ Sbjct: 58 GNGVIDIPEFMDLI 71 >2OPO-A nrPDB Length = 86 Score = 33.9 bits (76), Expect = 0.035, Method: Compositional matrix adjust. Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 6/59 (10%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 F+ +D + DG IS+ EL LK + G+ D V + + D DGDG ISF+EF Sbjct: 17 FKRFDTNGDGKISSSELGDALKTL-GSVTPDE-----VRRMMAEIDTDGDGFISFDEFT 69 Score = 26.2 bits (56), Expect = 6.9, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 5/55 (9%) Query: 27 FKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 FK+ D + G +S E +L + + V+R++ DTDG+G + F EF + Sbjct: 17 FKRFDTNGDGKISSSELGDALKTLGSVTPDE-VRRMMAEIDTDGDGFISFDEFTD 70 >2Q4U-A nrPDB Length = 272 Score = 33.5 bits (75), Expect = 0.050, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 3/66 (4%) Query: 96 FRIYDMDKDGYISNGELFQVLK---MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 +R YD D GYIS EL LK + + +L + D + DK+ DGR+ + Sbjct: 110 WRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLND 169 Query: 153 FCAVVG 158 ++ Sbjct: 170 LARILA 175 >2WCE-A nrPDB Length = 95 Score = 33.1 bits (74), Expect = 0.055, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 36/65 (55%), Gaps = 2/65 (3%) Query: 96 FRIYDMDKDGY--ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 F Y + K + +S GEL Q+L + N +K+ + + ++D+ D + D ++ F+EF Sbjct: 18 FHQYSVRKGHFDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEF 77 Query: 154 CAVVG 158 ++V Sbjct: 78 ISMVA 82 >1SR6-C nrPDB Length = 156 Score = 33.1 bits (74), Expect = 0.062, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 3/63 (4%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF+ +D + G+IS EL VL + G L D + +I+ T + D +G+ + +E+F Sbjct: 89 AFKTFDREGQGFISGAELRHVLTAL-GERLSDEDVDEIIKLTDLQEDLEGN--VKYEDFV 145 Query: 155 AVV 157 V Sbjct: 146 KKV 148 >2KQY-A nrPDB Length = 108 Score = 33.1 bits (74), Expect = 0.065, Method: Compositional matrix adjust. Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 7/88 (7%) Query: 71 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ 130 ++K F V S D+ +K+ F I D DK G+I EL LK + T + Sbjct: 25 NYKSFFSTVGLSSKTPDQIKKV---FGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAE 81 Query: 131 QIVDKTIINA-DKDGDGRISFEEFCAVV 157 K + A D DGDG+I EEF ++V Sbjct: 82 T---KAFLAAGDTDGDGKIGVEEFQSLV 106 >2M8U-A nrPDB Length = 77 Score = 32.7 bits (73), Expect = 0.083, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 5/63 (7%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF+++D D +GY++ L +VL N L D +++ I AD G + +E F Sbjct: 16 AFKVFDRDGNGYVTVDYLRKVL-----NELGDMMPADEIEEMIYEADPQNSGYVQYETFV 70 Query: 155 AVV 157 ++ Sbjct: 71 GML 73 >2KGR-A nrPDB Length = 111 Score = 32.3 bits (72), Expect = 0.094, Method: Compositional matrix adjust. Identities = 20/86 (23%), Positives = 41/86 (47%), Gaps = 7/86 (8%) Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKT 136 V++++V K R F +D G+++ Q +++ ++L QL I + + Sbjct: 1 PPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGP---QARTILMQSSLPQAQLASIWNLS 57 Query: 137 IINADKDGDGRISFEEFCAVVGGLDI 162 D D DG+++ EEF + +D+ Sbjct: 58 ----DIDQDGKLTAEEFILAMHLIDV 79 >3DF0-A nrPDB Length = 714 Score = 32.3 bits (72), Expect = 0.10, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 15/90 (16%) Query: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 117 ++D+ D DG+G++ KEF + K QK + +R D+D+ G +++ E+ + L+ Sbjct: 580 MVDMLDEDGSGKLGLKEFY-------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALE 632 Query: 118 MMVGNNLKDTQLQQIV------DKTIINAD 141 G L QL Q++ D+ II+ D Sbjct: 633 -EAGFKLP-CQLHQVIVARFADDELIIDFD 660 >1ZMZ-A nrPDB Length = 98 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 9/86 (10%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSL-PEL--QQNPLVQRVIDIFDTDGNGEVDFKEFIEGV 79 + FKK ++ +S S + MS PEL +Q ++ D+FD DG G +D KE + Sbjct: 1 MASNFKKANMASS---SQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAM 57 Query: 80 SQFSVKGDKEQKLRFAFRIYDMDKDG 105 + KE+ + I ++DK+G Sbjct: 58 RALGFEPKKEEIKKM---ISEIDKEG 80 Score = 31.2 bits (69), Expect = 0.23, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 42/71 (59%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 +++Q++R AF ++D D G I EL +V +G K ++++++ + DK+G G Sbjct: 28 EQKQEIREAFDLFDADGTGTIDVKEL-KVAMRALGFEPKKEEIKKMISEI----DKEGTG 82 Query: 147 RISFEEFCAVV 157 +++F +F V+ Sbjct: 83 KMNFGDFLTVM 93 >1KFU-L nrPDB Length = 699 Score = 32.3 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 15/90 (16%) Query: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 117 ++D+ D+DG+G++ KEF + K QK + +R D+D+ G +++ E+ + L+ Sbjct: 579 MVDMLDSDGSGKLGLKEFY-------ILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALE 631 Query: 118 MMVGNNLKDTQLQQIV------DKTIINAD 141 G + QL Q++ D+ II+ D Sbjct: 632 -EAGFKMP-CQLHQVIVARFADDQLIIDFD 659 >3I5I-C nrPDB Length = 159 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 7/109 (6%) Query: 49 LQQNPLVQRVIDIFDTDGNGEVDFK--EFIEGVSQFSVK--GDKEQKLRFAFRIYDMDKD 104 L NP +V T GE +K E + + S K G + AF+ +D + Sbjct: 40 LGMNPTEAQVHQHGGTKKMGEKAYKLEEILPIYEEMSSKDTGTAADEFMEAFKTFDREGQ 99 Query: 105 GYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 G IS+ E+ VLKM+ G + + Q I T + +D DG I +E+ Sbjct: 100 GLISSAEIRNVLKML-GERITEDQCNDIF--TFCDIREDIDGNIKYEDL 145 >4D1E-A nrPDB Length = 876 Score = 32.3 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 18/56 (32%), Positives = 32/56 (57%), Gaps = 1/56 (1%) Query: 57 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 R++ + D +G G V F+ FI+ +++ + D +++ +FRI DK YI EL Sbjct: 778 RIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKP-YILAEEL 832 >2NLN-A nrPDB Length = 108 Score = 32.3 bits (72), Expect = 0.12, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 6/64 (9%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGN--NLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 FR D D+ GY+ EL L+ + L +++ + ++D AD DGDG+I +EF Sbjct: 47 FRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDA----ADNDGDGKIGADEF 102 Query: 154 CAVV 157 +V Sbjct: 103 QEMV 106 >2KYF-A nrPDB Length = 108 Score = 32.0 bits (71), Expect = 0.14, Method: Compositional matrix adjust. Identities = 25/68 (36%), Positives = 34/68 (50%), Gaps = 4/68 (5%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA-DKDGDGRIS 149 +L+ FRI D D+ G+I EL L+ T + KT + A D DGDG+I Sbjct: 42 QLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASET---KTFLAAADHDGDGKIG 98 Query: 150 FEEFCAVV 157 EEF +V Sbjct: 99 AEEFQEMV 106 >2LUC-A nrPDB Length = 105 Score = 32.0 bits (71), Expect = 0.14, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 32/63 (50%), Gaps = 3/63 (4%) Query: 103 KDGY---ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 KDGY +S E + + K+ + ++D+ + D + DG++ F EF ++GG Sbjct: 27 KDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFLNLIGG 86 Query: 160 LDI 162 L + Sbjct: 87 LAM 89 Score = 26.9 bits (58), Expect = 4.9, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 30/49 (61%), Gaps = 9/49 (18%) Query: 37 SLSVEEFMSL--PEL------QQNP-LVQRVIDIFDTDGNGEVDFKEFI 76 +LS EF+S EL Q++P ++ R++ DT+ +G++DF EF+ Sbjct: 33 TLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFL 81 >1TTX-A nrPDB Length = 109 Score = 32.0 bits (71), Expect = 0.14, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 6/64 (9%) Query: 96 FRIYDMDKDGYISNGEL-FQVLKMMVG-NNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 FR D D+ GY+ EL F + K G L +++ + + + AD DGDG+I EEF Sbjct: 48 FRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSL----MAAADNDGDGKIGAEEF 103 Query: 154 CAVV 157 +V Sbjct: 104 QEMV 107 >1SJJ-A nrPDB Length = 863 Score = 32.0 bits (71), Expect = 0.14, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 5/99 (5%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFK 73 +++ F D +G + E+F +S+ R++ I D + G V F+ Sbjct: 722 EQMNEFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPNRMGVVTFQ 781 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 FI+ +S+ + D ++ +F+I DK+ YI+ EL Sbjct: 782 AFIDFMSRETADTDTADQVMASFKILAGDKN-YITVDEL 819 >1A75-A nrPDB Length = 108 Score = 32.0 bits (71), Expect = 0.15, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 8/81 (9%) Query: 80 SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL---FQVLKMMVGNNLKDTQLQQIVDKT 136 ++ + G ++ AF D DK G+I EL QV K L D + + + Sbjct: 31 AKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGA-RALTDAETKAFLK-- 87 Query: 137 IINADKDGDGRISFEEFCAVV 157 D DGDG I EE+ A+V Sbjct: 88 --AGDSDGDGAIGVEEWVALV 106 >5B7X-A nrPDB Length = 156 Score = 31.6 bits (70), Expect = 0.16, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 14/86 (16%) Query: 73 KEF-IEG----VSQFSVKGDKEQ--------KLRFAFRIYDMDKDGYISNGELFQVLKMM 119 KEF IEG + QF + ++EQ KLR AF ++D DKDG I +L L Sbjct: 56 KEFAIEGETFQIEQFELIMEREQSKPDTREIKLRKAFEVFDQDKDGKIKASDLAHNL-TT 114 Query: 120 VGNNLKDTQLQQIVDKTIINADKDGD 145 VG+ + +++++ I + D D Sbjct: 115 VGDKMTKEEVEKVFSILGITMESDID 140 >4HRG-A nrPDB Length = 115 Score = 31.6 bits (70), Expect = 0.16, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 + + F F + DK GY++ +L +++ L++ + VDK + + D+ DG++ Sbjct: 11 ETMMFTFHKFAGDK-GYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKDLDQCRDGKVG 69 Query: 150 FEEFCAVVGGLDI 162 F+ F +++ GL I Sbjct: 70 FQSFFSLIAGLTI 82 >4FTG-A nrPDB Length = 96 Score = 31.6 bits (70), Expect = 0.16, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 + + F F + DK GY++ +L +++ L++ + VDK + + D+ DG++ Sbjct: 9 ETMMFTFHKFAGDK-GYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKDLDQCRDGKVG 67 Query: 150 FEEFCAVVGGLDI 162 F+ F +++ GL I Sbjct: 68 FQSFFSLIAGLTI 80 >1QX2-A nrPDB Length = 76 Score = 31.6 bits (70), Expect = 0.17, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 40/71 (56%), Gaps = 7/71 (9%) Query: 90 QKLRFAFRIYDMDKDG---YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 ++++ AF ++ K+G IS EL V++ + + LK +D+ I DK+GDG Sbjct: 5 EEIKGAFEVFAA-KEGDPNQISKEELKLVMQTLGPSLLKGMS---TLDEMIEEVDKNGDG 60 Query: 147 RISFEEFCAVV 157 +SFEEF ++ Sbjct: 61 EVSFEEFLVMM 71 >5HYD-A nrPDB Length = 99 Score = 31.6 bits (70), Expect = 0.20, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 29/56 (51%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S GEL +L+ + L + Q+VDK + + D + D + F EF +V L + Sbjct: 29 LSKGELKLLLQRELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVAALTV 84 Score = 28.5 bits (62), Expect = 1.5, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 4/62 (6%) Query: 25 KRFK--KLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQF 82 KRFK K +L + EF+S ++ LV +++ D + + EVDF EF+ V+ Sbjct: 25 KRFKLSKGELKLLLQRELTEFLSCQ--KETQLVDKIVQDLDANKDNEVDFNEFVVMVAAL 82 Query: 83 SV 84 +V Sbjct: 83 TV 84 >4OCI-A nrPDB Length = 146 Score = 31.2 bits (69), Expect = 0.20, Method: Compositional matrix adjust. Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 9/126 (7%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDT-DGNGEV---DFKEFIEG 78 L + F D D G L++ EF SL + +V I T + N +V ++ F Sbjct: 8 LKESFLLFDGDGDGYLTLNEFESLVRVL--GVVMETSAIASTYNSNSKVRGMSYELFTSC 65 Query: 79 VSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII 138 SQ K + +++ A + D DK G+I EL ++L +G+N++ ++ + T + Sbjct: 66 FSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILS-TIGDNMEQKEITDLF--TFM 122 Query: 139 NADKDG 144 D+ G Sbjct: 123 GIDEQG 128 >1BU3-A nrPDB Length = 109 Score = 31.2 bits (69), Expect = 0.23, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA-DKDGDGRISFEEF 153 AF + D DK G+I EL L++ T + K + A D DGDG I +E+ Sbjct: 47 AFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAET---KAFLKAGDSDGDGAIGVDEW 103 Query: 154 CAVV 157 A+V Sbjct: 104 AALV 107 >5VP3-A nrPDB Length = 206 Score = 31.2 bits (69), Expect = 0.24, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 19/29 (65%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPE 48 ++RL KRF DLD G ++++E M P+ Sbjct: 33 LERLYKRFDTFDLDTDGKMTMDEIMYWPD 61 >6AGI-A nrPDB Length = 382 Score = 31.2 bits (69), Expect = 0.25, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 9/78 (11%) Query: 31 DLDNSGSLSVEEFMSLPELQQNPLV--QRVIDIFDTDGNGEVDFKEFIEGVSQF------ 82 +L G +S E++ L + P + ++FDTDGN VD KEF+ F Sbjct: 81 NLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEK 140 Query: 83 -SVKGDKEQKLRFAFRIY 99 +KGD+E++ ++Y Sbjct: 141 REIKGDEEKRAMLRLQLY 158 >1QXP-A nrPDB Length = 900 Score = 31.2 bits (69), Expect = 0.26, Method: Compositional matrix adjust. Identities = 20/79 (25%), Positives = 42/79 (53%), Gaps = 9/79 (11%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 + ++++ D DGNG++ G+ +F++ ++ + FR +D+DK G +S E+ Sbjct: 579 CRSMVNLMDRDGNGKL-------GLVEFNILWNRIRNYLTIFRKFDLDKSGSMSAYEMRM 631 Query: 115 VLKMMVGNNLKDTQLQQIV 133 ++ G L QL Q++ Sbjct: 632 AIE-AAGFKLP-CQLHQVI 648 Score = 26.9 bits (58), Expect = 3.9, Method: Compositional matrix adjust. Identities = 31/152 (20%), Positives = 65/152 (42%), Gaps = 28/152 (18%) Query: 25 KRFKKLDLDNSG---SLSVEEFMSL--------PELQQNPL----VQRVIDIFDTDGNGE 69 ++F+KL + +G +S E M++ P+L+ + + ++ + D+D G+ Sbjct: 731 RQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGK 790 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 + F+E F + +K + ++ ++ D+ G I + EL + L Sbjct: 791 LGFEE-------FKYLWNNIKKWQGIYKRFETDRSGTIGSNELPGAFEA------AGFHL 837 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 Q + II D G + F+ F + + LD Sbjct: 838 NQHIYSMIIRRYSDETGNMDFDNFISCLVRLD 869 >1TIZ-A nrPDB Length = 67 Score = 30.8 bits (68), Expect = 0.28, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 6/60 (10%) Query: 27 FKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQ 81 F+K D + G LS++EF + P Q +V+ +I D DGNGE++ EF + + Sbjct: 7 FEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEI-DVDGNGELNADEFTSCIEK 65 >2G9B-A nrPDB Length = 263 Score = 30.8 bits (68), Expect = 0.30, Method: Compositional matrix adjust. Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 19/127 (14%) Query: 25 KRFKKLDLDNSGSLSVEEFMS-LPELQQNP-----------LVQRVIDIFDTDGNGEVDF 72 K ++K D D+SG + EE + L +L + ++ +FD++ +G+++ Sbjct: 107 KTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLEL 166 Query: 73 KEFIEGVS---QFSVK--GDKEQKLRF--AFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 E + F +K G K F AF +YD D +GYI EL +LK + N + Sbjct: 167 TEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQ 226 Query: 126 DTQLQQI 132 + + I Sbjct: 227 ELDINNI 233 Score = 30.8 bits (68), Expect = 0.34, Method: Compositional matrix adjust. Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 24/168 (14%) Query: 5 ASYPLEMCSHFDADEIKRL-GKRFKKLDLDNSGSLSVEEFMSLPE---LQQNPLVQRVID 60 AS E+ HFDAD L GK + L ++E + + L+ +P ++ +D Sbjct: 15 ASQFFEIWLHFDADGSGYLEGKELQNL---------IQELLQARKKAGLELSPEMKTFVD 65 Query: 61 IFDTDGNGEVDFKEFIEGVSQ-------FSVKGDKE-QKLRFAFRIYDMDKDGYISNGEL 112 + +G++ E + F + K ++ +R YD D G+I EL Sbjct: 66 QYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL 125 Query: 113 FQVLKMMV---GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 LK ++ + DT+L + D + D + DG++ E ++ Sbjct: 126 KNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 173 >1NSH-A nrPDB Length = 101 Score = 30.8 bits (68), Expect = 0.34, Method: Compositional matrix adjust. Identities = 16/63 (25%), Positives = 33/63 (52%), Gaps = 3/63 (4%) Query: 103 KDGY---ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 KDG+ +S E + + K+ + ++D+ + D + DG++ F+EF ++GG Sbjct: 23 KDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGG 82 Query: 160 LDI 162 L + Sbjct: 83 LAV 85 >1ZFS-A nrPDB Length = 93 Score = 30.4 bits (67), Expect = 0.45, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 30/56 (53%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S EL +L+ + + L + VDK + D++GDG + F+EF +V L + Sbjct: 28 LSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAALTV 83 Score = 29.3 bits (64), Expect = 0.81, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 28/44 (63%), Gaps = 1/44 (2%) Query: 42 EFMSLPELQQNP-LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 E S ++Q++ V +++ D +G+GEVDF+EF+ V+ +V Sbjct: 40 ELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAALTV 83 >1N2D-A nrPDB Length = 148 Score = 30.0 bits (66), Expect = 0.47, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 4/59 (6%) Query: 25 KRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGV 79 K F+ D +++G +SV + L E + V ++ + D NGE+D+K+FIE V Sbjct: 87 KAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFIEDV 145 Score = 26.6 bits (57), Expect = 6.4, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 5/60 (8%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF+++D + G +S G+L +L + G L D + VD+ + + D +G I +++F Sbjct: 88 AFQVFDKESTGKVSVGDLRYMLTGL-GEKLTDAE----VDELLKGVEVDSNGEIDYKKFI 142 >1QLS-A nrPDB Length = 99 Score = 30.0 bits (66), Expect = 0.48, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 21/31 (67%) Query: 132 IVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 ++D+ + D D DG++ F+EF ++GGL I Sbjct: 57 VLDRMMKKLDLDSDGQLDFQEFLNLIGGLAI 87 Score = 26.6 bits (57), Expect = 5.9, Method: Compositional matrix adjust. Identities = 11/44 (25%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Query: 42 EFMSLPELQQNP-LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 E + + Q++P ++ R++ D D +G++DF+EF+ + ++ Sbjct: 44 ELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFLNLIGGLAI 87 Score = 26.6 bits (57), Expect = 6.1, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 17/24 (70%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSL 46 L + KKLDLD+ G L +EF++L Sbjct: 58 LDRMMKKLDLDSDGQLDFQEFLNL 81 >2FCE-A nrPDB Length = 70 Score = 30.0 bits (66), Expect = 0.48, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 4/59 (6%) Query: 25 KRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGV 79 K F+ D +++G +SV + L E + V ++ + D NGE+D+K+FIE V Sbjct: 9 KAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFIEDV 67 Score = 26.9 bits (58), Expect = 4.4, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 5/60 (8%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF+++D + G +S G+L +L + G L D + VD+ + + D +G I +++F Sbjct: 10 AFQVFDKESTGKVSVGDLRYMLTGL-GEKLTDAE----VDELLKGVEVDSNGEIDYKKFI 64 >5TBY-E nrPDB Length = 166 Score = 30.0 bits (66), Expect = 0.54, Method: Compositional matrix adjust. Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 8/69 (11%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 Q+ + AF I D ++DG+I +L + N+K+ ++ +++ K+ G I+ Sbjct: 27 QEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMI--------KEAPGPIN 78 Query: 150 FEEFCAVVG 158 F F + G Sbjct: 79 FTVFLTMFG 87 >2L0P-A nrPDB Length = 94 Score = 30.0 bits (66), Expect = 0.58, Method: Compositional matrix adjust. Identities = 16/56 (28%), Positives = 30/56 (53%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S EL ++L+ + L + VDK + D++GDG + F+E+ +V L + Sbjct: 29 LSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAALTV 84 Score = 28.1 bits (61), Expect = 1.8, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 21/30 (70%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 V +V+ D +G+GEVDF+E++ V+ +V Sbjct: 55 VDKVMKELDENGDGEVDFQEYVVLVAALTV 84 >2I18-A nrPDB Length = 64 Score = 29.6 bits (65), Expect = 0.62, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 35/63 (55%), Gaps = 9/63 (14%) Query: 92 LRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFE 151 L+ +++ D+D DG ++ E V + K ++++ ++ ++ AD +GDG I+ E Sbjct: 7 LKVLYKLMDVDGDGKLTKEE--------VTSFFKKHGIEKVAEQ-VMKADANGDGYITLE 57 Query: 152 EFC 154 EF Sbjct: 58 EFL 60 >3AKA-A nrPDB Length = 166 Score = 29.6 bits (65), Expect = 0.68, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 3/61 (4%) Query: 52 NPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGE 111 P + + + DTDG+G V + ++ F V E R A D D DG + E Sbjct: 97 RPFLHAALGVADTDGDGAVTVADTARALTAFGV---PEDLARQAAAALDTDGDGKVGETE 153 Query: 112 L 112 + Sbjct: 154 I 154 >2Y5I-A nrPDB Length = 99 Score = 29.3 bits (64), Expect = 0.79, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 26/36 (72%), Gaps = 1/36 (2%) Query: 50 QQNP-LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 Q++P LV+++++ D++ + EVDF EF+ V+ +V Sbjct: 49 QKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVAALTV 84 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 15/56 (26%), Positives = 29/56 (51%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S GEL ++L + + L + +V+K + + D + D + F EF +V L + Sbjct: 29 LSKGELKELLNAELTDFLMSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVAALTV 84 >1NYA-A nrPDB Length = 176 Score = 29.3 bits (64), Expect = 0.79, Method: Compositional matrix adjust. Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 39/161 (24%) Query: 22 RLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTD-GNGEVDFKEFIEGVS 80 RL KRF + D D +G+L +F Q + + F D G EV Sbjct: 8 RLKKRFDRWDFDGNGALERADF--------EKEAQHIAEAFGKDAGAAEV---------- 49 Query: 81 QFSVKGDKEQKLRFAF-RIYD-------MDKDGYISNGELFQVLKMMV---GNNLKDTQL 129 Q L+ AF ++D + DG ++ + +V + ++ G + L Sbjct: 50 ---------QTLKNAFGGLFDYLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVL 100 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 +V + DK+ DG+I+ +EF A + L + K + Sbjct: 101 GPVVKGIVGMCDKNADGQINADEFAAWLTALGMSKAEAAEA 141 >4NSC-A nrPDB Length = 401 Score = 29.3 bits (64), Expect = 0.84, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 22/34 (64%) Query: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQK 91 V +FD DGNGE+ KEF+ + Q ++G ++ K Sbjct: 341 VFALFDCDGNGELSNKEFVSIMKQRLMRGLEKPK 374 Score = 26.6 bits (57), Expect = 6.2, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 6/48 (12%) Query: 32 LDNSGSLSVEEFMSLPELQQNPLVQRVIDI----FDTDGNGEVDFKEF 75 L G +S +++ L + P QR +I FD +G+GEVD +EF Sbjct: 123 LGECGLISFSDYIFLTTVLSTP--QRNFEIAFKMFDLNGDGEVDMEEF 168 >4OKH-A nrPDB Length = 189 Score = 29.3 bits (64), Expect = 0.85, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 10/86 (11%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 + +I + DTDG+G+++ +EF K QK+ F+ YD D+ G I++ E+ Sbjct: 57 CRSMIALMDTDGSGKLNLQEF----HHLWNKIKAWQKI---FKHYDTDQSGTINSYEMRN 109 Query: 115 VLK---MMVGNNLKDTQLQQIVDKTI 137 + + N L D + DK + Sbjct: 110 AVNDAGFHLNNQLYDIITMRYADKHM 135 Score = 28.1 bits (61), Expect = 1.9, Method: Compositional matrix adjust. Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 6/83 (7%) Query: 30 LDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKE 89 +D D SG L+++EF L + Q++ +DTD +G ++ E V+ + + Sbjct: 64 MDTDGSGKLNLQEFHHL--WNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQ 121 Query: 90 Q----KLRFAFRIYDMDKDGYIS 108 +R+A + ++D D +I Sbjct: 122 LYDIITMRYADKHMNIDFDSFIC 144 Score = 27.3 bits (59), Expect = 3.0, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 10/97 (10%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPE---LQQNPLVQRVIDIFDTDGNGEV 70 H ++IK K FK D D SG+++ E + N + +I + D + + Sbjct: 78 HHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNI 137 Query: 71 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYI 107 DF FI + E R AF +D D DG I Sbjct: 138 DFDSFICCFVRL------EGMFR-AFHAFDKDGDGII 167 >1CB1-A nrPDB Length = 78 Score = 29.3 bits (64), Expect = 0.94, Method: Compositional matrix adjust. Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 3/51 (5%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 +S EL Q+++ + LK + +D DK+GDG +SFEEF +V Sbjct: 26 LSKEELKQLIQAEFPSLLKGPR---TLDDLFQELDKNGDGEVSFEEFQVLV 73 >6MI5-X nrPDB Length = 117 Score = 29.3 bits (64), Expect = 0.99, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 43/116 (37%), Gaps = 23/116 (19%) Query: 53 PLVQRVIDI--FDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNG 110 P +DI FD D +G +D KE + S AF D DKDG + Sbjct: 1 PTTTTKVDIAAFDPDKDGTIDLKEALAAGSA-------------AFDKLDPDKDGTLDAK 47 Query: 111 ELF-----QVLKMMVGNN---LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 EL LK + +N L + V+ A+ D DG I E + G Sbjct: 48 ELKGRVSEADLKKLDPDNDGTLDKKEYLAAVEAQFKAANPDNDGTIDARELASPAG 103 Score = 27.7 bits (60), Expect = 2.8, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 16/66 (24%) Query: 15 FDADEIK-RLGKR-FKKLDLDNSGSLSVEEFMSLPELQ---QNPLVQRVIDIFDTDGNGE 69 DA E+K R+ + KKLD DN G+L +E+++ E Q NP D +G Sbjct: 44 LDAKELKGRVSEADLKKLDPDNDGTLDKKEYLAAVEAQFKAANP-----------DNDGT 92 Query: 70 VDFKEF 75 +D +E Sbjct: 93 IDAREL 98 >2LVV-A nrPDB Length = 226 Score = 28.9 bits (63), Expect = 1.1, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 8/74 (10%) Query: 7 YPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL----VQRVIDI 61 + L +C +D E+ + F +D D S L ++EF +LP+L++ + V + Sbjct: 122 FRLMLCYIYDIFELTVM---FDTMDKDGSLLLELQEFKEALPKLKEWGVDITDATTVFNE 178 Query: 62 FDTDGNGEVDFKEF 75 DT+G+G V F EF Sbjct: 179 IDTNGSGVVTFDEF 192 >4L9M-A nrPDB Length = 559 Score = 28.9 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 13/26 (50%), Positives = 16/26 (61%) Query: 128 QLQQIVDKTIINADKDGDGRISFEEF 153 +Q++VD N D D DG IS EEF Sbjct: 422 HVQRMVDSVFKNYDHDQDGYISQEEF 447 Score = 28.1 bits (61), Expect = 1.9, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 14/62 (22%) Query: 55 VQRVIDI----FDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNG 110 VQR++D +D D +G + +EF + + F F+F + D D++G IS Sbjct: 423 VQRMVDSVFKNYDHDQDGYISQEEFEKIAASFP----------FSFCVMDKDREGLISRD 472 Query: 111 EL 112 E+ Sbjct: 473 EI 474 >3BOW-B nrPDB Length = 184 Score = 28.5 bits (62), Expect = 1.3, Method: Compositional matrix adjust. Identities = 32/152 (21%), Positives = 65/152 (42%), Gaps = 28/152 (18%) Query: 25 KRFKKLDLDNSG---SLSVEEFMSL--------PELQQNPL----VQRVIDIFDTDGNGE 69 ++F+KL + +G +S E M++ P+L+ + + ++ + D+D G+ Sbjct: 15 RQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGK 74 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 + F+E F + +K + ++ +D D+ G I + EL + L Sbjct: 75 LGFEE-------FKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEA------AGFHL 121 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 Q + II D G + F+ F + + LD Sbjct: 122 NQHIYSMIIRRYSDETGNMDFDNFISCLVRLD 153 >1BOD-A nrPDB Length = 74 Score = 28.5 bits (62), Expect = 1.3, Method: Compositional matrix adjust. Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 ++L+ F YD + DG +S EL +L+ + LK +D+ DK+GDG +S Sbjct: 5 EELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMS---TLDELFEELDKNGDGEVS 61 Query: 150 FEEFCAVV 157 FEEF +V Sbjct: 62 FEEFQVLV 69 >6EAZ-A nrPDB Length = 379 Score = 28.5 bits (62), Expect = 1.4, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 22/38 (57%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQI 132 F+I+D+D D +S+GE VLK + L +Q Q + Sbjct: 314 VFKIFDLDGDECLSHGEFLGVLKNRMHRGLWVSQQQSV 351 >1NP8-A nrPDB Length = 159 Score = 28.5 bits (62), Expect = 1.5, Method: Compositional matrix adjust. Identities = 32/152 (21%), Positives = 65/152 (42%), Gaps = 28/152 (18%) Query: 25 KRFKKLDLDNSG---SLSVEEFMSL--------PELQQNPL----VQRVIDIFDTDGNGE 69 ++F+KL + +G +S E M++ P+L+ + + ++ + D+D G+ Sbjct: 11 RQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGK 70 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 + F+E F + +K + ++ +D D+ G I + EL + L Sbjct: 71 LGFEE-------FKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEA------AGFHL 117 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 Q + II D G + F+ F + + LD Sbjct: 118 NQHIYSMIIRRYSDETGNMDFDNFISCLVRLD 149 >5I2L-A nrPDB Length = 120 Score = 28.5 bits (62), Expect = 1.5, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 5/61 (8%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 F+ YD +DG+I EL K+M+ L Q + I D+D D ++SF EF Sbjct: 37 FKQYDAGRDGFIDLMEL----KLMM-EKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLL 91 Query: 156 V 156 + Sbjct: 92 I 92 >4NQG-A nrPDB Length = 197 Score = 28.5 bits (62), Expect = 1.6, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 1/48 (2%) Query: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDG 105 + DI D DGNG V E+I+ ++ + Q F D+D DG Sbjct: 119 LFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQ-CEATFAHCDLDGDG 165 >2HPS-A nrPDB Length = 186 Score = 28.1 bits (61), Expect = 1.8, Method: Compositional matrix adjust. Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 11/61 (18%) Query: 100 DMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII---NADKDGDGRISFEEFCAV 156 D DKDGY+S E F+ VG +L D DK I D + +G+IS +EF Sbjct: 112 DTDKDGYVSLPE-FKAFLQAVGPDLTD-------DKAITCFNTLDFNKNGQISRDEFLVT 163 Query: 157 V 157 V Sbjct: 164 V 164 >4MN0-A nrPDB Length = 208 Score = 28.1 bits (61), Expect = 1.9, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 18/29 (62%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPE 48 + RL KRF DLD+ G + ++E + P+ Sbjct: 35 LSRLYKRFDTFDLDSDGKMEMDEVLYWPD 63 >1KQV-A nrPDB Length = 79 Score = 28.1 bits (61), Expect = 2.1, Method: Compositional matrix adjust. Identities = 12/26 (46%), Positives = 17/26 (65%) Query: 132 IVDKTIINADKDGDGRISFEEFCAVV 157 +D+ DK+GDG +SFEEF +V Sbjct: 49 TLDELFEELDKNGDGEVSFEEFQVLV 74 >1KFX-S nrPDB Length = 184 Score = 27.7 bits (60), Expect = 2.3, Method: Compositional matrix adjust. Identities = 30/158 (18%), Positives = 69/158 (43%), Gaps = 26/158 (16%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSL--------PELQQNPL----VQRVIDIFD 63 +++E+++ + F +L D+ +S E M++ P+L+ + + ++ + D Sbjct: 10 ESEEVRQFRRLFAQLAGDDM-EVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMD 68 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNN 123 +D G++ F+E F + ++ + ++ +D D+ G I + EL + Sbjct: 69 SDTTGKLGFEE-------FKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEA----- 116 Query: 124 LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 L + + II D G + F+ F + + LD Sbjct: 117 -AGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLD 153 Score = 27.7 bits (60), Expect = 2.5, Method: Compositional matrix adjust. Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 24/97 (24%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEF--------MSLPELQQNPLVQRVIDIFDTDGNGE 69 + IKR +K+ D D SG++ E L E N +++R +D +G Sbjct: 85 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRY-----SDESGN 139 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIY-DMDKDG 105 +DF FI + +L FR + +DKDG Sbjct: 140 MDFDNFISCLV----------RLDAMFRAFKSLDKDG 166 >2MA2-A nrPDB Length = 81 Score = 27.3 bits (59), Expect = 3.4, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 19/31 (61%) Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 ++++V+ N D DGDG IS EEF + G Sbjct: 10 HIEKMVESVFRNFDVDGDGHISQEEFQIIRG 40 >2MBX-A nrPDB Length = 109 Score = 27.3 bits (59), Expect = 3.7, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 9/92 (9%) Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN-NLKD 126 G D K F ++ + ++ F I D DK ++ EL K+ + N + Sbjct: 23 GSFDHKAFF---TKVGLAAKSPADIKKVFEIIDQDKSDFVEEDEL----KLFLQNFSAGA 75 Query: 127 TQLQQIVDKTIINA-DKDGDGRISFEEFCAVV 157 L K + A D DGDG+I +EF A++ Sbjct: 76 RALSDAETKVFLKAGDSDGDGKIGVDEFGAMI 107 >1S36-A nrPDB Length = 195 Score = 26.9 bits (58), Expect = 4.1, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 23/48 (47%), Gaps = 1/48 (2%) Query: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDG 105 V DIFD DG+G + E+ + + S ++ FR D+D G Sbjct: 118 VFDIFDKDGSGTITLDEW-KAYGKISGISPSQEDCEATFRHCDLDNSG 164 Score = 26.6 bits (57), Expect = 6.0, Method: Compositional matrix adjust. Identities = 27/115 (23%), Positives = 46/115 (40%), Gaps = 15/115 (13%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQ---FSVKGDKEQKLRFA------FRIYDMDKDGY 106 + + D D +GNG++ E + S ++ EQ R FR M+ Sbjct: 23 KHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCGMEYGKE 82 Query: 107 ISNGELFQVLKMMVGNNLK------DTQLQQIVDKTIINADKDGDGRISFEEFCA 155 I+ + K + + LK T +++ D DKDG G I+ +E+ A Sbjct: 83 IAFPQFLDGFKQLATSELKKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKA 137 >1B7T-Y nrPDB Length = 156 Score = 26.9 bits (58), Expect = 4.2, Method: Compositional matrix adjust. Identities = 16/67 (23%), Positives = 35/67 (52%), Gaps = 9/67 (13%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 Q+++ AF + D+D+DG++S E + + +G D +L ++ K+ G ++ Sbjct: 18 QEMKEAFSMIDVDRDGFVSK-EDIKAISEQLGRAPDDKELTAML--------KEAPGPLN 68 Query: 150 FEEFCAV 156 F F ++ Sbjct: 69 FTMFLSI 75 >5H53-B nrPDB Length = 146 Score = 26.9 bits (58), Expect = 4.7, Method: Compositional matrix adjust. Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 8/69 (11%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 Q+ + AF + D ++DG I +L M N+K+ +L ++ K+ G I+ Sbjct: 5 QEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMM--------KEASGPIN 56 Query: 150 FEEFCAVVG 158 F F + G Sbjct: 57 FTVFLTMFG 65 >1DFK-Y nrPDB Length = 139 Score = 26.9 bits (58), Expect = 4.7, Method: Compositional matrix adjust. Identities = 15/67 (22%), Positives = 36/67 (53%), Gaps = 9/67 (13%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 Q+++ AF + D+D+DG++S ++ + + +G D +L ++ K+ G ++ Sbjct: 7 QEMKEAFSMIDVDRDGFVSKEDI-KAISEQLGRAPDDKELTAML--------KEAPGPLN 57 Query: 150 FEEFCAV 156 F F ++ Sbjct: 58 FTMFLSI 64 >5ZH6-A nrPDB Length = 107 Score = 26.6 bits (57), Expect = 5.0, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 12/67 (17%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA-----DKDGDGRISF 150 F I D D+ G+I EL L+ N T + +D+T NA D D DG+I Sbjct: 46 FDILDQDRSGFIEVDELKLFLQ-----NFSATARE--LDETETNAFLAAGDSDHDGKIGV 98 Query: 151 EEFCAVV 157 +EF A+V Sbjct: 99 DEFKAMV 105 >3DTP-E nrPDB Length = 196 Score = 26.6 bits (57), Expect = 5.1, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 9/69 (13%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 Q+ + AF++ D DKDG+IS ++ ++L +Q +D + A G I+ Sbjct: 57 QEFKEAFQLIDQDKDGFISKNDIRATF-----DSLGRLCTEQELDSMVAEA----PGPIN 107 Query: 150 FEEFCAVVG 158 F F + G Sbjct: 108 FTMFLTIFG 116 >1IJ5-A nrPDB Length = 323 Score = 26.6 bits (57), Expect = 5.4, Method: Compositional matrix adjust. Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 24/149 (16%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMS---LPELQQNPLVQRVIDIFDTDGNGEVDFK 73 A+++ L F+K+D +++G+LS +EF + + + D D + +V F Sbjct: 184 ANDLAALVADFRKIDTNSNGTLSRKEFREHFVRLGFDKKSVQDALFRYADEDESDDVGFS 243 Query: 74 EFIE-GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQI 132 E++ G+ LR + D DK G +S E+ +V L+D + + Sbjct: 244 EYVHLGLCLLV--------LRILYAFADFDKSGQLSKEEVQKV--------LEDAHIPES 287 Query: 133 VDKTIIN----ADKDGDGRISFEEFCAVV 157 K + D D +S++EF +V Sbjct: 288 ARKKFEHQFSVVDVDDSKSLSYQEFVMLV 316 >1I84-U nrPDB Length = 166 Score = 26.6 bits (57), Expect = 5.5, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 8/64 (12%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF + D + DG I +L + M N+K+ +L ++ K+ G I+F F Sbjct: 30 AFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMI--------KEASGPINFTVFL 81 Query: 155 AVVG 158 + G Sbjct: 82 TMFG 85 >2JOJ-A nrPDB Length = 77 Score = 26.6 bits (57), Expect = 5.6, Method: Compositional matrix adjust. Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 1/73 (1%) Query: 50 QQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISN 109 +Q ++ D+FDT+ G +D+ E + K + L YD + +GYI Sbjct: 4 EQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILEL-MNEYDREGNGYIGF 62 Query: 110 GELFQVLKMMVGN 122 + ++ + N Sbjct: 63 DDFLDIMTEKIKN 75 >1O1A-B nrPDB Length = 145 Score = 26.6 bits (57), Expect = 5.6, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 8/64 (12%) Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF + D + DG I +L + M N+K+ +L ++ K+ G I+F F Sbjct: 12 AFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMI--------KEASGPINFTVFL 63 Query: 155 AVVG 158 + G Sbjct: 64 TMFG 67 >6DS2-B nrPDB Length = 114 Score = 26.6 bits (57), Expect = 5.7, Method: Compositional matrix adjust. Identities = 16/63 (25%), Positives = 38/63 (60%), Gaps = 3/63 (4%) Query: 107 ISNGELFQVLKMMVGNNLK-DTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI--H 163 ++ GE ++++ + N LK + + +++++ + + D + D ++SFEEF ++ L H Sbjct: 32 LNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARLTWASH 91 Query: 164 KKM 166 +KM Sbjct: 92 EKM 94 >2JTT-A nrPDB Length = 90 Score = 26.6 bits (57), Expect = 6.2, Method: Compositional matrix adjust. Identities = 13/56 (23%), Positives = 35/56 (62%), Gaps = 6/56 (10%) Query: 107 ISNGELFQVLK--MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 +S EL ++++ + +G+ L+D ++ +++D + D++ D ++F+E+ +G L Sbjct: 29 LSKKELKELIQKELTIGSKLQDAEIVKLMD----DLDRNKDQEVNFQEYITFLGAL 80 >3KPX-A nrPDB Length = 198 Score = 26.6 bits (57), Expect = 6.4, Method: Compositional matrix adjust. Identities = 12/18 (66%), Positives = 13/18 (72%) Query: 25 KRFKKLDLDNSGSLSVEE 42 K FK DLDNSG L V+E Sbjct: 156 KTFKHCDLDNSGKLDVDE 173 >2MJW-B nrPDB Length = 94 Score = 26.6 bits (57), Expect = 6.4, Method: Compositional matrix adjust. Identities = 14/54 (25%), Positives = 29/54 (53%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 ++ GEL +++ + L+ + + VDK + + D +GD ++ F EF V + Sbjct: 28 LTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAI 81 >5Z1Q-A nrPDB Length = 95 Score = 26.2 bits (56), Expect = 6.7, Method: Compositional matrix adjust. Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 1/73 (1%) Query: 50 QQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISN 109 +Q ++ D+FDT+ G +D+ E + K + L YD + +GYI Sbjct: 24 EQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILEL-MNEYDREGNGYIGF 82 Query: 110 GELFQVLKMMVGN 122 + ++ + N Sbjct: 83 DDFLDIMTEKIKN 95 >3ERV-A nrPDB Length = 236 Score = 26.2 bits (56), Expect = 7.5, Method: Compositional matrix adjust. Identities = 24/94 (25%), Positives = 35/94 (37%), Gaps = 26/94 (27%) Query: 94 FAFRIYDMDKDGY-ISNGELFQVLKMMVGNNLKDTQLQQI----------------VDKT 136 F IY + GY + +G LFQ+ K + N D + I + T Sbjct: 93 FVGNIYTFSESGYGVYHGPLFQLAKKYLPNKAVDLTGKSIEELYKSVKAGQPVVIITNAT 152 Query: 137 IINADKD---------GDGRISFEEFCAVVGGLD 161 D+D GD I++ E C V+ G D Sbjct: 153 FAPLDEDEFTTWETNNGDVSITYNEHCVVLIGYD 186 >2KY4-A nrPDB Length = 149 Score = 25.8 bits (55), Expect = 8.8, Method: Compositional matrix adjust. Identities = 10/14 (71%), Positives = 12/14 (85%) Query: 66 GNGEVDFKEFIEGV 79 GNGE+ KEFIEG+ Sbjct: 49 GNGEITVKEFIEGL 62 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4IL1-A nrPDB 209 6e-55 4ORC-B nrPDB 195 8e-51 3U0K-A nrPDB 172 1e-43 3EK4-A nrPDB 171 1e-43 4OY4-A nrPDB 170 2e-43 4I2Y-A nrPDB 165 7e-42 5UKG-A nrPDB 165 7e-42 5B8I-B nrPDB 155 8e-39 3WFN-B nrPDB 153 4e-38 2N6A-A nrPDB 151 2e-37 2F2P-A nrPDB 148 1e-36 6O20-F nrPDB 148 1e-36 4E53-A nrPDB 145 7e-36 6HCS-A nrPDB 143 5e-35 5I0I-E nrPDB 138 9e-34 2E30-A nrPDB 138 1e-33 2BEC-A nrPDB 137 2e-33 1CLM-A nrPDB 136 6e-33 5A2H-A nrPDB 135 8e-33 1GGZ-A nrPDB 134 2e-32 5T7C-A nrPDB 128 1e-30 1BJF-A nrPDB 126 5e-30 2LHI-A nrPDB 123 3e-29 2L1W-A nrPDB 123 5e-29 1V1G-A nrPDB 121 1e-28 2L2E-A nrPDB 121 2e-28 2LAP-A nrPDB 120 3e-28 2LMV-A nrPDB 119 5e-28 5M6C-E nrPDB 119 5e-28 4MVF-A nrPDB 119 8e-28 4DS7-A nrPDB 118 9e-28 2JUL-A nrPDB 118 1e-27 2JU0-A nrPDB 118 2e-27 3DD4-A nrPDB 116 4e-27 5D43-A nrPDB 116 4e-27 2LCP-A nrPDB 116 4e-27 2GGM-A nrPDB 116 4e-27 1LKJ-A nrPDB 116 6e-27 3QRX-A nrPDB 115 8e-27 1S1E-A nrPDB 115 9e-27 1S6C-A nrPDB 115 1e-26 3LIJ-A nrPDB 113 3e-26 3HZT-A nrPDB 113 3e-26 2R2I-A nrPDB 112 6e-26 3KF9-A nrPDB 112 9e-26 2ZFD-A nrPDB 111 2e-25 5JN2-A nrPDB 111 2e-25 3Q5I-A nrPDB 110 3e-25 3PM8-A nrPDB 110 3e-25 2TN4-A nrPDB 110 4e-25 4RGJ-A nrPDB 108 1e-24 2NA0-A nrPDB 108 1e-24 1TOP-A nrPDB 108 1e-24 6EPA-A nrPDB 108 1e-24 1UHN-A nrPDB 108 2e-24 4WPX-A nrPDB 108 2e-24 2AAO-A nrPDB 107 2e-24 4YZB-A nrPDB 106 3e-24 3NCG-A nrPDB 106 5e-24 3L19-A nrPDB 105 1e-23 1JBA-A nrPDB 105 1e-23 2OBH-A nrPDB 105 1e-23 3FWC-A nrPDB 103 4e-23 2GGZ-A nrPDB 103 5e-23 1S6I-A nrPDB 103 6e-23 2LHH-A nrPDB 102 9e-23 3KHE-A nrPDB 102 9e-23 2I94-A nrPDB 101 1e-22 3O4Y-A nrPDB 100 4e-22 4JWQ-A nrPDB 100 5e-22 2D8N-A nrPDB 99 9e-22 2JNF-A nrPDB 98 2e-21 2M29-A nrPDB 97 3e-21 3K21-A nrPDB 97 3e-21 5ZOR-A nrPDB 97 3e-21 2LC5-A nrPDB 95 1e-20 1DTL-A nrPDB 93 6e-20 1DGU-A nrPDB 92 9e-20 5E37-A nrPDB 92 9e-20 2LM5-A nrPDB 91 2e-19 4N5X-A nrPDB 91 3e-19 2BL0-B nrPDB 88 2e-18 4ZCV-A nrPDB 86 8e-18 2JNX-A nrPDB 86 8e-18 1JFJ-A nrPDB 82 9e-17 3IFK-A nrPDB 82 1e-16 1GGW-A nrPDB 82 2e-16 5YPX-A nrPDB 81 2e-16 3AAJ-A nrPDB 79 1e-15 5COC-A nrPDB 77 4e-15 2HF5-A nrPDB 75 1e-14 1FW4-A nrPDB 75 1e-14 2KN2-A nrPDB 75 1e-14 2KZ2-A nrPDB 74 3e-14 1M39-A nrPDB 73 4e-14 5H7D-E nrPDB 72 1e-13 3MSE-B nrPDB 72 2e-13 2LV7-A nrPDB 71 2e-13 2RO9-A nrPDB 71 3e-13 2M5E-A nrPDB 71 3e-13 2ROB-A nrPDB 70 5e-13 2RO8-A nrPDB 69 1e-12 2I08-A nrPDB 69 1e-12 2K7C-A nrPDB 68 1e-12 3SIA-A nrPDB 68 2e-12 2E6W-A nrPDB 67 3e-12 5JOJ-A nrPDB 67 6e-12 5JOL-A nrPDB 66 9e-12 4Q57-A nrPDB 65 2e-11 2K2I-A nrPDB 64 3e-11 2B1U-A nrPDB 64 3e-11 1JC2-A nrPDB 62 2e-10 2K2A-A nrPDB 61 3e-10 5ZGM-A nrPDB 60 4e-10 2M97-A nrPDB 58 2e-09 5PAL-A nrPDB 57 3e-09 2N7L-C nrPDB 57 4e-09 1OZS-A nrPDB 56 5e-09 2L50-A nrPDB 56 6e-09 5VLN-A nrPDB 56 6e-09 1TNP-A nrPDB 56 7e-09 1TRF-A nrPDB 56 1e-08 6IIE-A nrPDB 55 1e-08 1RTP-1 nrPDB 55 2e-08 2PMY-A nrPDB 50 5e-07 1G33-A nrPDB 45 2e-05 Sequences not found previously or not previously below threshold: 3J04-B nrPDB 79 8e-16 5MWC-D nrPDB 79 1e-15 2BL0-C nrPDB 77 5e-15 3JAX-C nrPDB 77 5e-15 1W7I-B nrPDB 74 3e-14 3DTP-E nrPDB 72 2e-13 3I5H-B nrPDB 70 5e-13 3E3R-A nrPDB 69 7e-13 5TBY-E nrPDB 68 2e-12 6FSA-D nrPDB 68 3e-12 1B7T-Y nrPDB 67 4e-12 5H53-C nrPDB 66 1e-11 5TBY-C nrPDB 66 1e-11 2AMI-A nrPDB 65 1e-11 1DFK-Y nrPDB 64 3e-11 2OS8-B nrPDB 64 3e-11 1Y1X-A nrPDB 63 5e-11 1I84-U nrPDB 63 7e-11 1F55-A nrPDB 61 2e-10 2N8Y-A nrPDB 61 2e-10 5H53-B nrPDB 61 2e-10 1O1A-B nrPDB 61 2e-10 1SR6-C nrPDB 61 2e-10 4D1E-A nrPDB 60 4e-10 1SJJ-A nrPDB 60 4e-10 5B7X-A nrPDB 59 1e-09 1OQP-A nrPDB 59 1e-09 2W4G-C nrPDB 59 1e-09 3TS5-B nrPDB 59 1e-09 2KSZ-A nrPDB 58 2e-09 1ZMZ-A nrPDB 58 3e-09 5XND-A nrPDB 57 3e-09 2G9B-A nrPDB 57 4e-09 1N2D-A nrPDB 57 5e-09 3JBH-C nrPDB 56 1e-08 2EC6-B nrPDB 56 1e-08 3AKA-A nrPDB 55 2e-08 1C7W-A nrPDB 55 2e-08 4OCI-A nrPDB 55 2e-08 5Z1Q-A nrPDB 54 3e-08 1YX7-A nrPDB 53 5e-08 3I5I-C nrPDB 53 7e-08 5OTJ-D nrPDB 53 7e-08 1RK9-A nrPDB 53 9e-08 2M8U-A nrPDB 53 9e-08 2LVV-A nrPDB 52 9e-08 2JOJ-A nrPDB 52 1e-07 4GJF-A nrPDB 52 1e-07 1QX2-A nrPDB 52 1e-07 2Q4U-A nrPDB 52 1e-07 3PAT-A nrPDB 51 3e-07 1S6J-A nrPDB 51 3e-07 1H4B-A nrPDB 50 4e-07 2OPO-A nrPDB 50 5e-07 2LVK-A nrPDB 50 5e-07 4P5X-A nrPDB 50 6e-07 1JF0-A nrPDB 50 7e-07 5ZH6-A nrPDB 49 1e-06 4P5W-A nrPDB 49 1e-06 3KPX-A nrPDB 48 2e-06 2KYF-A nrPDB 48 2e-06 2KQY-A nrPDB 48 2e-06 3TZ1-A nrPDB 48 2e-06 1IJ5-A nrPDB 48 2e-06 2K7B-A nrPDB 48 3e-06 5E1J-A nrPDB 48 3e-06 3CS1-A nrPDB 47 3e-06 1QXP-A nrPDB 47 4e-06 2I18-A nrPDB 47 5e-06 4PAL-A nrPDB 47 5e-06 1S36-A nrPDB 46 6e-06 1KFX-S nrPDB 46 7e-06 1ZFS-A nrPDB 46 1e-05 2M1U-A nrPDB 45 1e-05 4OKH-A nrPDB 45 1e-05 2LUC-A nrPDB 45 2e-05 1A75-A nrPDB 45 2e-05 1BU3-A nrPDB 44 3e-05 5XOP-A nrPDB 44 3e-05 5VE9-A nrPDB 44 3e-05 2WCE-A nrPDB 44 3e-05 5HYD-A nrPDB 44 3e-05 2M7M-A nrPDB 44 3e-05 1NSH-A nrPDB 44 3e-05 2L0P-A nrPDB 44 4e-05 1Q80-A nrPDB 44 4e-05 1TTX-A nrPDB 43 5e-05 3BOW-B nrPDB 43 5e-05 4L9M-A nrPDB 43 5e-05 5VT9-A nrPDB 43 5e-05 1JUO-A nrPDB 43 5e-05 5CPV-A nrPDB 43 6e-05 1QLS-A nrPDB 43 8e-05 2NLN-A nrPDB 43 9e-05 1TIZ-A nrPDB 43 9e-05 1BOD-A nrPDB 42 1e-04 1NYA-A nrPDB 42 1e-04 3H4S-E nrPDB 42 1e-04 2VRG-A nrPDB 42 1e-04 5MRA-A nrPDB 42 1e-04 4I5L-B nrPDB 42 1e-04 3A4U-B nrPDB 42 1e-04 1CB1-A nrPDB 42 1e-04 2M7L-A nrPDB 42 2e-04 2MBX-A nrPDB 41 2e-04 5I2L-A nrPDB 41 2e-04 1SL8-A nrPDB 41 2e-04 3LCP-C nrPDB 41 2e-04 4YGB-B nrPDB 41 3e-04 2NCO-A nrPDB 41 3e-04 4MEW-A nrPDB 41 3e-04 1GJY-A nrPDB 41 3e-04 5CSF-A nrPDB 40 4e-04 4NQG-A nrPDB 40 6e-04 1KFU-L nrPDB 40 6e-04 2HPS-A nrPDB 40 7e-04 4HRG-A nrPDB 40 8e-04 4FTG-A nrPDB 39 8e-04 1F4Q-A nrPDB 39 9e-04 2FCE-A nrPDB 39 0.001 3DF0-A nrPDB 39 0.001 2Y5I-A nrPDB 39 0.001 4MSP-A nrPDB 39 0.001 1UHK-A nrPDB 39 0.001 4I5K-A nrPDB 38 0.001 2MJW-B nrPDB 38 0.002 6MI5-X nrPDB 38 0.003 2MA2-A nrPDB 38 0.003 2KGR-A nrPDB 38 0.003 1NP8-A nrPDB 37 0.004 2SAS-A nrPDB 36 0.005 6DS2-B nrPDB 36 0.007 1KQV-A nrPDB 36 0.009 5LPU-C nrPDB 36 0.010 6EAZ-A nrPDB 36 0.010 4CFQ-A nrPDB 36 0.011 6DU8-A nrPDB 35 0.013 5W1A-B nrPDB 35 0.018 2AUC-A nrPDB 35 0.018 4YBH-B nrPDB 35 0.018 3NSO-A nrPDB 35 0.020 6AGH-A nrPDB 34 0.026 4NSC-A nrPDB 34 0.031 4DUQ-A nrPDB 34 0.038 4AOM-A nrPDB 33 0.054 5HLO-A nrPDB 33 0.057 6AGI-A nrPDB 33 0.065 2JTT-A nrPDB 33 0.073 2VTG-A nrPDB 33 0.078 2MHH-A nrPDB 32 0.15 2G2B-A nrPDB 32 0.15 5C5V-A nrPDB 32 0.15 5NRM-B nrPDB 32 0.17 5CUY-A nrPDB 31 0.18 1C07-A nrPDB 31 0.18 4C0K-A nrPDB 31 0.21 5CUU-A nrPDB 31 0.22 3A8R-A nrPDB 31 0.22 2JXC-A nrPDB 31 0.23 1WY9-A nrPDB 31 0.25 5VP3-A nrPDB 31 0.29 5KU1-A nrPDB 30 0.43 5NRK-B nrPDB 30 0.59 1IQ3-A nrPDB 30 0.60 5X2E-A nrPDB 30 0.66 2D58-A nrPDB 30 0.70 2KHN-A nrPDB 29 0.86 4JB3-A nrPDB 29 0.93 5MKE-A nrPDB 29 1.0 1NUB-A nrPDB 29 1.1 2CXJ-A nrPDB 29 1.1 6D1W-A nrPDB 29 1.2 2JQ6-A nrPDB 29 1.3 1YUT-A nrPDB 29 1.3 2KAY-A nrPDB 28 1.5 2KFH-A nrPDB 28 1.5 3VSL-A nrPDB 28 1.6 4TX3-A nrPDB 28 1.7 4MN0-A nrPDB 28 2.0 5MVF-A nrPDB 28 2.1 4U3S-B nrPDB 28 2.3 4GFT-A nrPDB 28 2.4 2JMM-A nrPDB 28 2.8 1DJX-A nrPDB 28 2.9 4F4Z-B nrPDB 28 3.0 5EX6-C nrPDB 27 3.2 4PCW-A nrPDB 27 3.3 6IBE-A nrPDB 27 3.3 1PHK-A nrPDB 27 3.4 2UVV-A nrPDB 27 3.9 4CJ1-A nrPDB 27 4.2 2QPT-A nrPDB 26 5.8 1NKS-A nrPDB 26 6.3 4WI0-B nrPDB 26 6.4 4N9F-U nrPDB 26 6.6 1FI6-A nrPDB 26 6.6 2Y3N-B nrPDB 26 6.9 1SRA-A nrPDB 26 7.1 4AQI-A nrPDB 26 7.6 4JGH-D nrPDB 26 7.9 1EUC-B nrPDB 26 8.1 3ICE-A nrPDB 26 8.2 5J6D-A nrPDB 26 8.3 3OZ6-A nrPDB 26 8.6 6EM8-A nrPDB 26 9.2 1OHZ-B nrPDB 26 9.2 6G18-t nrPDB 26 9.7 >4IL1-A nrPDB Length = 823 Score = 209 bits (531), Expect = 6e-55, Method: Composition-based stats. Identities = 168/168 (100%), Positives = 168/168 (100%) Query: 3 NEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF 62 NEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF Sbjct: 160 NEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF 219 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN Sbjct: 220 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 279 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV Sbjct: 280 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 327 Score = 172 bits (436), Expect = 7e-44, Method: Composition-based stats. Identities = 52/153 (33%), Positives = 85/153 (55%), Gaps = 9/153 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ + G L D Sbjct: 61 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTD 119 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + VD+ I AD DGDG++++EEF ++ Sbjct: 120 EE----VDEMIREADIDGDGQVNYEEFVQMMTA 148 Score = 83.5 bits (205), Expect = 4e-17, Method: Composition-based stats. Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 34/172 (19%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E + L V +I D DG+G+V+ Sbjct: 79 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 138 Query: 72 FKEFIEGVSQFSV---------------------KGDKEQKLRFAFRIYDMDKDGYISNG 110 ++EF++ ++ D+ ++L F+ D+D G +S Sbjct: 139 YEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVE 198 Query: 111 ELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 E +L + Q +V + I D DG+G + F+EF V + Sbjct: 199 EFM---------SLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSV 241 >4ORC-B nrPDB Length = 170 Score = 195 bits (496), Expect = 8e-51, Method: Composition-based stats. Identities = 170/170 (100%), Positives = 170/170 (100%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID 60 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID Sbjct: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID 60 Query: 61 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV 120 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV Sbjct: 61 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV 120 Query: 121 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV Sbjct: 121 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 >3U0K-A nrPDB Length = 442 Score = 172 bits (435), Expect = 1e-43, Method: Composition-based stats. Identities = 50/154 (32%), Positives = 84/154 (54%), Gaps = 9/154 (5%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTD 65 ++I + F D D G+++ +E + + L QNP +Q +I+ D D Sbjct: 293 PTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD 352 Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 G+G +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ + G L Sbjct: 353 GDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLT 411 Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 D + VD+ I AD DGDG++++EEF ++ Sbjct: 412 DEE----VDEMIREADIDGDGQVNYEEFVQMMTA 441 Score = 56.9 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E + L V +I D DG+G+V+ Sbjct: 372 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 431 Query: 72 FKEFIEGVSQF 82 ++EF++ ++ Sbjct: 432 YEEFVQMMTAK 442 >3EK4-A nrPDB Length = 451 Score = 171 bits (433), Expect = 1e-43, Method: Composition-based stats. Identities = 55/164 (33%), Positives = 90/164 (54%), Gaps = 11/164 (6%) Query: 2 GNEASYPLEMCSH--FDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---V 55 GN + LE + ++I + F D D G+++ +E + + L QNP + Sbjct: 292 GNILGHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAEL 351 Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 Q +I+ D DGNG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V Sbjct: 352 QDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 411 Query: 116 LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + + G L D + VD+ I AD DGDG++++EEF ++ Sbjct: 412 MTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTA 450 Score = 55.3 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E + L V +I D DG+G+V+ Sbjct: 381 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 440 Query: 72 FKEFIEGVSQF 82 ++EF++ ++ Sbjct: 441 YEEFVQMMTAK 451 >4OY4-A nrPDB Length = 415 Score = 170 bits (431), Expect = 2e-43, Method: Composition-based stats. Identities = 54/163 (33%), Positives = 89/163 (54%), Gaps = 10/163 (6%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGN 67 ++I + F D D G+++ +E + + L QNP +Q +I+ D DG+ Sbjct: 9 SDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGD 68 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 G +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ + G L D Sbjct: 69 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTDE 127 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVV-GGLDIHKKMVVD 169 + VD+ I AD DGDG++++EEF ++ L+ K V D Sbjct: 128 E----VDEMIREADIDGDGQVNYEEFVQMMTAKLECEKMYVRD 166 >4I2Y-A nrPDB Length = 421 Score = 165 bits (419), Expect = 7e-42, Method: Composition-based stats. Identities = 53/163 (32%), Positives = 87/163 (53%), Gaps = 14/163 (8%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ 56 MG EA+ ++I + F D D G+++ +E + + L QNP +Q Sbjct: 268 MGWEATR-----DQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ 322 Query: 57 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL 116 +I+ D DG+G DF EF+ +++ D E+++R AFR++D D +GYI EL V+ Sbjct: 323 DMINEVDADGDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVM 382 Query: 117 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + G L D + VD+ I AD DGDG++++EEF ++ Sbjct: 383 TDL-GEKLTDEE----VDEMIRVADIDGDGQVNYEEFVQMMTA 420 Score = 53.4 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G + E + L V +I + D DG+G+V+ Sbjct: 351 DTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVN 410 Query: 72 FKEFIEGVSQF 82 ++EF++ ++ Sbjct: 411 YEEFVQMMTAK 421 >5UKG-A nrPDB Length = 419 Score = 165 bits (418), Expect = 7e-42, Method: Composition-based stats. Identities = 52/163 (31%), Positives = 86/163 (52%), Gaps = 14/163 (8%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ 56 +G EAS ++I + F D D G+++ +E + + L QNP +Q Sbjct: 266 LGWEAS-----NGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ 320 Query: 57 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL 116 +I+ D DG+G DF EF+ +++ E+++R AFR++D D +GYI EL V+ Sbjct: 321 DMINEVDADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVM 380 Query: 117 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + G L D + VD+ I AD DGDG++++EEF ++ Sbjct: 381 TDL-GEKLTDEE----VDEMIRVADIDGDGQVNYEEFVQMMTA 418 Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 49/126 (38%), Gaps = 14/126 (11%) Query: 35 SGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRF 94 +G L+ E+ + +FD DG+G + KE + + + E +L+ Sbjct: 272 NGQLTEEQIAEF---------KEAFSLFDKDGDGTITTKELGTVM-RSLGQNPTEAELQD 321 Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 D D DG E ++ + + + ++++ DKDG+G I E Sbjct: 322 MINEVDADGDGTFDFPEFLTMMARKMSYRVTEEEIRE----AFRVFDKDGNGYIGAAELR 377 Query: 155 AVVGGL 160 V+ L Sbjct: 378 HVMTDL 383 Score = 55.3 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 38/78 (48%), Gaps = 7/78 (8%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDT 64 +M +EI + F+ D D +G + E + +L + V +I + D Sbjct: 345 RKMSYRVTEEEI---REAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADI 401 Query: 65 DGNGEVDFKEFIEGVSQF 82 DG+G+V+++EF++ ++ Sbjct: 402 DGDGQVNYEEFVQMMTAK 419 >5B8I-B nrPDB Length = 171 Score = 155 bits (392), Expect = 8e-39, Method: Composition-based stats. Identities = 100/157 (63%), Positives = 126/157 (80%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDF 72 S+FD +E+ RL KRF KLD D SG++ +EF+SLP++ NPL R+I IFD DG G+VDF Sbjct: 13 SNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLSTRMIAIFDEDGGGDVDF 72 Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQI 132 +EF+ G+S FS KG+KE+KLRFAF++YD+D+DG+ISNGELF VLKMMVG+NLKD QLQQI Sbjct: 73 QEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNLKDMQLQQI 132 Query: 133 VDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVD 169 VDKTI+ AD DGDGRISFEEF +V D+ M +D Sbjct: 133 VDKTIMEADLDGDGRISFEEFTRMVENTDVSMSMTLD 169 >3WFN-B nrPDB Length = 182 Score = 153 bits (386), Expect = 4e-38, Method: Composition-based stats. Identities = 52/153 (33%), Positives = 85/153 (55%), Gaps = 9/153 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 7 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 66 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ + G L D Sbjct: 67 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTD 125 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + VD+ I AD DGDG++++EEF ++ Sbjct: 126 EE----VDEMIREADIDGDGQVNYEEFVQMMTA 154 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 4/78 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E + L V +I D DG+G+V+ Sbjct: 85 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 144 Query: 72 FKEFIEGVSQFSVKGDKE 89 ++EF++ ++ G +E Sbjct: 145 YEEFVQMMTAKGGGGGEE 162 >2N6A-A nrPDB Length = 173 Score = 151 bits (381), Expect = 2e-37, Method: Composition-based stats. Identities = 52/150 (34%), Positives = 85/150 (56%), Gaps = 9/150 (6%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVD 71 ++I + F D D G+++ +E + + L QNP +Q +I+ D DGNG +D Sbjct: 7 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTID 66 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 F EF+ +++ D E+++R AFR++D D +GYIS EL V+ + G L D + Sbjct: 67 FPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTDEE--- 122 Query: 132 IVDKTIINADKDGDGRISFEEFCAVVGGLD 161 VD+ I AD DGDG++++EEF ++ G Sbjct: 123 -VDEMIREADIDGDGQVNYEEFVQMMTGAS 151 >2F2P-A nrPDB Length = 179 Score = 148 bits (374), Expect = 1e-36, Method: Composition-based stats. Identities = 52/153 (33%), Positives = 85/153 (55%), Gaps = 9/153 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ + G L D Sbjct: 61 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTD 119 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + VD+ I AD DGDG++++EEF ++ Sbjct: 120 EE----VDEMIREADIDGDGQVNYEEFVQMMTA 148 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E + L V +I D DG+G+V+ Sbjct: 79 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 138 Query: 72 FKEFIEGVSQF 82 ++EF++ ++ Sbjct: 139 YEEFVQMMTAK 149 >6O20-F nrPDB Length = 169 Score = 148 bits (374), Expect = 1e-36, Method: Composition-based stats. Identities = 52/153 (33%), Positives = 85/153 (55%), Gaps = 9/153 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 21 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 80 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ + G L D Sbjct: 81 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTD 139 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + VD+ I AD DGDG++++EEF ++ Sbjct: 140 EE----VDEMIREADIDGDGQVNYEEFVQMMTA 168 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E + L V +I D DG+G+V+ Sbjct: 99 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 158 Query: 72 FKEFIEGVSQF 82 ++EF++ ++ Sbjct: 159 YEEFVQMMTAK 169 >4E53-A nrPDB Length = 185 Score = 145 bits (367), Expect = 7e-36, Method: Composition-based stats. Identities = 52/151 (34%), Positives = 85/151 (56%), Gaps = 9/151 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 8 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 67 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ + G L D Sbjct: 68 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTD 126 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + VD+ I AD DGDG++++EEF ++ Sbjct: 127 EE----VDEMIREADIDGDGQVNYEEFVQMM 153 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 11/102 (10%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E + L V +I D DG+G+V+ Sbjct: 86 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 145 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113 ++EF++ ++ G K++ +FR G+I+ +L Sbjct: 146 YEEFVQMMTAKGGGGGAATKIQASFR-------GHITRKKLK 180 >6HCS-A nrPDB Length = 167 Score = 143 bits (360), Expect = 5e-35, Method: Composition-based stats. Identities = 51/153 (33%), Positives = 84/153 (54%), Gaps = 9/153 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M ++I + F D D G+++ +E + + L QNP +Q +I+ D DG Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E+++R AFR++D D +GYIS EL + + G L D Sbjct: 61 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNL-GEKLTD 119 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + VD+ I AD DGDG++++EEF ++ Sbjct: 120 EE----VDEMIREADIDGDGQVNYEEFVQMMTA 148 Score = 48.8 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E L V +I D DG+G+V+ Sbjct: 79 DTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKLTDEEVDEMIREADIDGDGQVN 138 Query: 72 FKEFIEGVSQFSVKGDKE 89 ++EF++ ++ E Sbjct: 139 YEEFVQMMTAKLEGTGLE 156 >5I0I-E nrPDB Length = 145 Score = 138 bits (349), Expect = 9e-34, Method: Composition-based stats. Identities = 51/150 (34%), Positives = 84/150 (56%), Gaps = 9/150 (6%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNG 68 ++I + F D D G+++ +E + + L QNP +Q +I+ D DGNG Sbjct: 1 DQLTEEQIAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNG 60 Query: 69 EVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQ 128 +DF EF+ +++ D E+++R AFR++D D +GYIS EL V+ + G L D + Sbjct: 61 TIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTDEE 119 Query: 129 LQQIVDKTIINADKDGDGRISFEEFCAVVG 158 VD+ I AD DGDG++++EEF ++ Sbjct: 120 ----VDEMIREADIDGDGQVNYEEFVQMMT 145 Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 5/69 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF + D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRSL-GQNPTEAELQDMINEV----DADGNGTIDF 64 Query: 151 EEFCAVVGG 159 EF ++ Sbjct: 65 PEFLTMMAR 73 >2E30-A nrPDB Length = 195 Score = 138 bits (347), Expect = 1e-33, Method: Composition-based stats. Identities = 74/182 (40%), Positives = 104/182 (57%), Gaps = 15/182 (8%) Query: 3 NEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF 62 +E ++ + F +I RL RF LD +G+LS E+F +PEL NPL R+I+ F Sbjct: 11 DEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAF 70 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKEQ---------------KLRFAFRIYDMDKDGYI 107 +G +V+F+ F+ ++ F D E+ KL FAFR+YD+DKD I Sbjct: 71 FPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEKI 130 Query: 108 SNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMV 167 S EL QVL+MMVG N+ D QL I D+TI AD+DGD ISF EF V+ +D+ +KM Sbjct: 131 SRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMS 190 Query: 168 VD 169 + Sbjct: 191 IR 192 >2BEC-A nrPDB Length = 202 Score = 137 bits (346), Expect = 2e-33, Method: Composition-based stats. Identities = 61/174 (35%), Positives = 96/174 (55%), Gaps = 16/174 (9%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDF 72 + F + RL RF+ LD + G LS + + L NPL R+I+ F DG+ VDF Sbjct: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDF 80 Query: 73 KEFIEGVSQFSVKGDKE----------------QKLRFAFRIYDMDKDGYISNGELFQVL 116 F+ ++ F D++ KL +AF++YD+D+DG IS E+ QVL Sbjct: 81 PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL 140 Query: 117 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 ++MVG + + QL+ I D+T+ AD+DGDG +SF EF + +D+ +KM + + Sbjct: 141 RLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 >1CLM-A nrPDB Length = 148 Score = 136 bits (342), Expect = 6e-33, Method: Composition-based stats. Identities = 50/150 (33%), Positives = 82/150 (54%), Gaps = 9/150 (6%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGN 67 ++I + F D D G+++ +E + + L QNP +Q +I+ D DGN Sbjct: 1 AQELTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 60 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 G +DF EF+ +++ + D E++L AF+++D D +G IS EL V+ + G L D Sbjct: 61 GTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNL-GEKLTDD 119 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + VD+ I AD DGDG I++EEF ++ Sbjct: 120 E----VDEMIREADIDGDGHINYEEFVRMM 145 Score = 60.3 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 5/69 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF ++D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F Sbjct: 11 EFKEAFALFDKDGDGTITTKELGTVMRSL-GQNPTEAELQDMINEV----DADGNGTIDF 65 Query: 151 EEFCAVVGG 159 EF +++ Sbjct: 66 PEFLSLMAR 74 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 5/105 (4%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 + +FD DG+G + KE + + + E +L+ D D +G I E + Sbjct: 13 KEAFALFDKDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLSL 71 Query: 116 LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 + +K+ ++ + + D+DG+G IS E V+ L Sbjct: 72 MAR----KMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNL 112 >5A2H-A nrPDB Length = 149 Score = 135 bits (341), Expect = 8e-33, Method: Composition-based stats. Identities = 54/151 (35%), Positives = 85/151 (56%), Gaps = 9/151 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M D+I + F D D G ++ +E + + L QNP +Q +I+ D DG Sbjct: 1 MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 NG +DF EF+ +++ D E++L+ AFR++D D++G+IS EL V+ + G L D Sbjct: 61 NGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNL-GEKLTD 119 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + VD+ I AD DGDG+I++EEF V+ Sbjct: 120 EE----VDEMIREADVDGDGQINYEEFVKVM 146 Score = 59.2 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 5/77 (6%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 + D+ + + AF ++D D DG I+ EL V++ + G N + +LQ ++++ D Sbjct: 4 QLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSL-GQNPTEAELQDMINEV----DA 58 Query: 143 DGDGRISFEEFCAVVGG 159 DG+G I F EF ++ Sbjct: 59 DGNGTIDFPEFLNLMAR 75 Score = 45.3 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDT 64 L D D + L + F+ D D +G +S E + L V +I D Sbjct: 72 LMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADV 131 Query: 65 DGNGEVDFKEFIEGVSQF 82 DG+G+++++EF++ + Sbjct: 132 DGDGQINYEEFVKVMMAK 149 >1GGZ-A nrPDB Length = 148 Score = 134 bits (337), Expect = 2e-32, Method: Composition-based stats. Identities = 48/150 (32%), Positives = 81/150 (54%), Gaps = 9/150 (6%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGN 67 +++ + F D D G ++ E + + L QNP ++ ++ D DGN Sbjct: 1 ADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGN 60 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 G VDF EF+ +++ D E+++R AFR++D D +G++S EL V+ + G L D Sbjct: 61 GTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRL-GEKLSDE 119 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + VD+ I AD DGDG++++EEF V+ Sbjct: 120 E----VDEMIRAADTDGDGQVNYEEFVRVL 145 Score = 60.7 bits (146), Expect = 3e-10, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF ++D D DG I+ EL V++ + G N + +L+ + D+DG+G + F Sbjct: 11 EFKEAFSLFDKDGDGCITTRELGTVMRSL-GQNPTEAELRD----MMSEIDRDGNGTVDF 65 Query: 151 EEFCAVVGG 159 EF ++ Sbjct: 66 PEFLGMMAR 74 Score = 48.8 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 5/105 (4%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 + +FD DG+G + +E + + + E +LR D D +G + E + Sbjct: 13 KEAFSLFDKDGDGCITTRELGTVM-RSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFLGM 71 Query: 116 LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 + +KDT ++ + + DKDG+G +S E V+ L Sbjct: 72 MAR----KMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRL 112 >5T7C-A nrPDB Length = 193 Score = 128 bits (322), Expect = 1e-30, Method: Composition-based stats. Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 15/164 (9%) Query: 4 EASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRV 58 E L + F E++ K F L +G L+V+EF + P + + V Sbjct: 11 EVLQDLRENTEFTDHELQEWYKGF--LKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHV 68 Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 FDT+G+G +DF+EFI +S S +G EQKL++AF +YD+D +GYIS E+ ++++ Sbjct: 69 FRTFDTNGDGTIDFREFIIALSVTS-RGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQA 127 Query: 119 M-------VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 + + ++ ++ DK D + DG++S EEF Sbjct: 128 IYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIR 171 >1BJF-A nrPDB Length = 193 Score = 126 bits (317), Expect = 5e-30, Method: Composition-based stats. Identities = 51/164 (31%), Positives = 83/164 (50%), Gaps = 15/164 (9%) Query: 4 EASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRV 58 E L + F EI+ K F L SG LS+EEF + P + + V Sbjct: 11 EVMQDLLESTDFTEHEIQEWYKGF--LRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHV 68 Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 FD +G+G +DF+EFI +S S +G EQKL++AF +YD+D +GYIS E+ ++++ Sbjct: 69 FRTFDANGDGTIDFREFIIALSVTS-RGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQA 127 Query: 119 M-------VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 + + ++ ++ +K D + DG++S EEF Sbjct: 128 IYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIR 171 >2LHI-A nrPDB Length = 176 Score = 123 bits (310), Expect = 3e-29, Method: Composition-based stats. Identities = 44/154 (28%), Positives = 78/154 (50%), Gaps = 10/154 (6%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQR---VIDIFDTDGN 67 S+ ++I + F D DN+GS+S E + + L +P +++ D DGN Sbjct: 2 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 61 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 +++F EF+ +S+ D EQ+L AF+++D + DG IS EL VL + G L D Sbjct: 62 HQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI-GEKLTDA 120 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 ++ ++ + DG G I+ ++F A++ Sbjct: 121 EVDDMLREV-----SDGSGEINIQQFAALLSKGS 149 Score = 45.3 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 5/82 (6%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFM----SLPELQQNPLVQRVIDIFDTDGNGEVD 71 D + L + FK D + G +S E S+ E + V ++ +DG+GE++ Sbjct: 79 SNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREV-SDGSGEIN 137 Query: 72 FKEFIEGVSQFSVKGDKEQKLR 93 ++F +S+ S G + + LR Sbjct: 138 IQQFAALLSKGSSTGTRRKALR 159 Score = 26.1 bits (56), Expect = 7.1, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 121 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +NL + Q+ + + DKD +G IS E V+ L + Sbjct: 2 SSNLTEEQIAEF-KEAFALFDKDNNGSISSSELATVMRSLGL 42 >2L1W-A nrPDB Length = 149 Score = 123 bits (308), Expect = 5e-29, Method: Composition-based stats. Identities = 50/147 (34%), Positives = 84/147 (57%), Gaps = 9/147 (6%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEV 70 ++I + F D D G ++VEE + + L QNP +Q +I D DGNG + Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTI 63 Query: 71 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ 130 +F EF+ +++ D E++L+ AF+++D D++GYIS EL V+ + G L D +++ Sbjct: 64 EFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINL-GEKLTDEEVE 122 Query: 131 QIVDKTIINADKDGDGRISFEEFCAVV 157 Q I AD DGDG++++EEF ++ Sbjct: 123 Q----MIKEADLDGDGQVNYEEFVKMM 145 Score = 55.0 bits (131), Expect = 1e-08, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 5/68 (7%) Query: 92 LRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFE 151 + AF ++D D DG I+ EL V++ L ++ + I D DG+G I F+ Sbjct: 12 FKEAFGLFDKDGDGCITVEELATVIRS-----LDQNPTEEELQDMISEVDADGNGTIEFD 66 Query: 152 EFCAVVGG 159 EF +++ Sbjct: 67 EFLSLMAK 74 >1V1G-A nrPDB Length = 222 Score = 121 bits (304), Expect = 1e-28, Method: Composition-based stats. Identities = 46/165 (27%), Positives = 84/165 (50%), Gaps = 8/165 (4%) Query: 2 GNEASYPLEMCSHFDADEIKRLGKRFKKLDL--DNSGSLSVEEFMSLP---ELQQNPLVQ 56 G E L + F +E++ L + FKKL + G + EEF ++N Sbjct: 18 GYEDPELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQLALFRNRNRRNLFAD 77 Query: 57 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL 116 R+ D+FD NG ++F EF+ + F +K++FAF++YD+ + G+I EL +++ Sbjct: 78 RIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELKEMV 137 Query: 117 KMMVGNN---LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 ++ + L + ++ +VDK + AD+ DG+I +E+ V Sbjct: 138 VALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVS 182 >2L2E-A nrPDB Length = 190 Score = 121 bits (304), Expect = 2e-28, Method: Composition-based stats. Identities = 55/178 (30%), Positives = 92/178 (51%), Gaps = 22/178 (12%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 L + FD E+++ K F SG L+ EF + P + + V ++FD Sbjct: 16 LVRSTRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFD 73 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MV 120 D NG +DFKEFI +S S +G+ KL +AF++YD+D +G IS E+ +++ MV Sbjct: 74 ADKNGYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMV 132 Query: 121 GNNLK----DTQLQQIVDKTIINADKDGDGRISFEEFC-------AVVGGLDIHKKMV 167 G+ +K + ++ V+K DK+ DG+++ EEFC +V L ++ +V Sbjct: 133 GSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 >2LAP-A nrPDB Length = 167 Score = 120 bits (301), Expect = 3e-28, Method: Composition-based stats. Identities = 47/171 (27%), Positives = 86/171 (50%), Gaps = 16/171 (9%) Query: 1 MGNEASYPLEMCSHFD----ADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLV 55 MGN YPL S D +EI+ L + F++ D D G ++ + + + + P Sbjct: 1 MGNCVKYPLRNLSRKDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTE 60 Query: 56 QRVID---IFDTDGNGEVDFKEFIEGVSQFSVKGDKE----QKLRFAFRIYDMDKDGYIS 108 +I+ + + G VDF +F+E + + + ++LR AFR +D + DG IS Sbjct: 61 MELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEIS 120 Query: 109 NGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 EL + ++ ++G+ + +++I I + D +GDGR+ FEEF ++ Sbjct: 121 TSELREAMRKLLGHQVGHRDIEEI----IRDVDLNGDGRVDFEEFVRMMSR 167 >2LMV-A nrPDB Length = 148 Score = 119 bits (299), Expect = 5e-28, Method: Composition-based stats. Identities = 46/150 (30%), Positives = 81/150 (54%), Gaps = 9/150 (6%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNG 68 S ++I F + D + +G ++ E + + L QNP +Q +I + + NG Sbjct: 2 SELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNG 61 Query: 69 EVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQ 128 +++F EF +++ + D E+++R AF+I+D D DG+IS EL V+ NL + Sbjct: 62 QLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVM-----INLGEKV 116 Query: 129 LQQIVDKTIINADKDGDGRISFEEFCAVVG 158 + +D+ I AD DGDG I++EEF ++ Sbjct: 117 TDEEIDEMIREADFDGDGMINYEEFVWMIS 146 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 38/69 (55%), Gaps = 5/69 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF +D + G I+ EL +++ + G N + +LQ + I A+ + +G+++F Sbjct: 11 EFKDAFVQFDKEGTGKIATRELGTLMRTL-GQNPTEAELQDL----IAEAENNNNGQLNF 65 Query: 151 EEFCAVVGG 159 EFC ++ Sbjct: 66 TEFCGIMAK 74 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 4/66 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFM----SLPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 76 + + + FK D D G +S E +L E + + +I D DG+G ++++EF+ Sbjct: 83 EEMREAFKIFDRDGDGFISPAELRFVMINLGEKVTDEEIDEMIREADFDGDGMINYEEFV 142 Query: 77 EGVSQF 82 +SQ Sbjct: 143 WMISQK 148 >5M6C-E nrPDB Length = 193 Score = 119 bits (299), Expect = 5e-28, Method: Composition-based stats. Identities = 48/164 (29%), Positives = 82/164 (50%), Gaps = 15/164 (9%) Query: 4 EASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRV 58 E L + F E++ K F L +G L+V+EF + P + + V Sbjct: 11 EMLQDLRENTEFSELELQEWYKGF--LKDCPTGILNVDEFKKIYANFFPYGDASKFAEHV 68 Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 FDT+ +G +DF+EFI +S S +G EQKL +AF +YD+D +GYIS E+ ++++ Sbjct: 69 FRNFDTNSDGTIDFREFIIALSVTS-RGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQA 127 Query: 119 M-------VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 + + ++ ++ +K D + DG++S EEF Sbjct: 128 IYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIR 171 >4MVF-A nrPDB Length = 506 Score = 119 bits (298), Expect = 8e-28, Method: Composition-based stats. Identities = 40/155 (25%), Positives = 76/155 (49%), Gaps = 8/155 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEE----FMSLPELQQNPLVQRVIDIFDTDG 66 + H EI L F LD+DNSG+LS +E + + P + +V+ D++ Sbjct: 350 IAKHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNA 409 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 +G++ + +F+ KE L F+ +D+D +G IS EL ++ +++++ Sbjct: 410 SGQIHYTDFLAATIDKQTYLKKEVCL-IPFKFFDIDGNGKISVEELKRIFGR---DDIEN 465 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 + + +D + D +GDG I F EF ++ L+ Sbjct: 466 PLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKLE 500 >4DS7-A nrPDB Length = 147 Score = 118 bits (297), Expect = 9e-28, Method: Composition-based stats. Identities = 46/153 (30%), Positives = 79/153 (51%), Gaps = 10/153 (6%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66 M + ++I + F D DNSGS+S E + + L +P V +++ D DG Sbjct: 1 MSQNLTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEAEVADLMNEIDVDG 60 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 N ++F EF+ +S+ D EQ+L AF+++D + DG IS EL VL + G L D Sbjct: 61 NHAIEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI-GEKLTD 119 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 ++ +++ + DG G I+ ++F A++ Sbjct: 120 AEVDEMLREV-----SDGSGEINIKQFAALLSK 147 Score = 26.1 bits (56), Expect = 8.2, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 19/43 (44%), Gaps = 1/43 (2%) Query: 120 VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 + NL + Q+ + + DKD G IS E V+ L + Sbjct: 1 MSQNLTEEQIAEF-KEAFALFDKDNSGSISASELATVMRSLGL 42 >2JUL-A nrPDB Length = 256 Score = 118 bits (295), Expect = 1e-27, Method: Composition-based stats. Identities = 41/163 (25%), Positives = 82/163 (50%), Gaps = 15/163 (9%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM-----SLPELQQNPLVQRVIDIFD 63 L+ + F E++ L + FK + +G + + F P+ + + FD Sbjct: 82 LQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFD 139 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MV 120 DGNG + F++F+ G+S ++G +KL++AF +YD++KDG I+ E+ ++K M+ Sbjct: 140 ADGNGAIHFEDFVVGLS-ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 Query: 121 GNN----LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 G + L++ + V++ D++ DG ++ +EF Sbjct: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 >2JU0-A nrPDB Length = 190 Score = 118 bits (295), Expect = 2e-27, Method: Composition-based stats. Identities = 51/178 (28%), Positives = 90/178 (50%), Gaps = 22/178 (12%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 L+ ++FD EI++ K F L SG L+ E+F+ + P + +FD Sbjct: 16 LKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFD 73 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF-------QVL 116 D NG + F+EFI +S + +G E+KL +AF +YD++ DGYI+ E+ +++ Sbjct: 74 KDNNGFIHFEEFITVLS-TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMM 132 Query: 117 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF-------CAVVGGLDIHKKMV 167 MV N + + V K DK+ DG I+ +EF +++G L+++ ++ Sbjct: 133 GSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI 190 >3DD4-A nrPDB Length = 229 Score = 116 bits (292), Expect = 4e-27, Method: Composition-based stats. Identities = 51/168 (30%), Positives = 85/168 (50%), Gaps = 15/168 (8%) Query: 4 EASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRV 58 EA LE S F E++ L + FK + SG ++ E F + P+ + Sbjct: 50 EALELLEAQSKFTKKELQILYRGFK--NECPSGVVNEETFKEIYSQFFPQGDSTTYAHFL 107 Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 + FDTD NG V F++FI+G+S ++G ++KL +AF +YD++KDGYI+ E+ ++K Sbjct: 108 FNAFDTDHNGAVSFEDFIKGLS-ILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA 166 Query: 119 MVGNN-------LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + LK+ +Q V+ DK+ DG ++ +EF Sbjct: 167 IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQK 214 >5D43-A nrPDB Length = 178 Score = 116 bits (291), Expect = 4e-27, Method: Composition-based stats. Identities = 42/154 (27%), Positives = 86/154 (55%), Gaps = 9/154 (5%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNP---LVQRVIDIFDTDGNGE 69 D+ + + + F D D SG++ V+E ++ L P ++++I D + G+ Sbjct: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 + F +F+ ++Q + D ++++ AFR++D D+ G IS L +V + G +L D +L Sbjct: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEEL 142 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 Q+++D+ AD+DGDG ++ EEF ++ +++ Sbjct: 143 QEMIDE----ADRDGDGEVNEEEFLKIMKKTNLY 172 >2LCP-A nrPDB Length = 190 Score = 116 bits (291), Expect = 4e-27, Method: Composition-based stats. Identities = 51/183 (27%), Positives = 92/183 (50%), Gaps = 22/183 (12%) Query: 4 EASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRV 58 E L ++F E+++ K F K SG L F + P V Sbjct: 11 EVVEELTRKTYFTEKEVQQWYKGFIK--DCPSGQLDAAGFQKIYKQFFPFGDPTKFATFV 68 Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 ++FD + +G ++F EFI+ +S S +G ++KLR+AF++YD+D DGYI+ E+ ++ Sbjct: 69 FNVFDENKDGRIEFSEFIQALSVTS-RGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDA 127 Query: 119 ---MVGNNL----KDTQLQQIVDKTIINADKDGDGRISFEEF-------CAVVGGLDIHK 164 MVGN + ++ ++ VD+ DK+ DG+++ +EF ++V L ++ Sbjct: 128 IYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYD 187 Query: 165 KMV 167 +V Sbjct: 188 GLV 190 >2GGM-A nrPDB Length = 172 Score = 116 bits (291), Expect = 4e-27, Method: Composition-based stats. Identities = 42/154 (27%), Positives = 88/154 (57%), Gaps = 9/154 (5%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL---VQRVIDIFDTDGNGE 69 ++ + + + F D D +G++ V+E ++ L P ++++I D +G G+ Sbjct: 24 ELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGK 83 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 ++F +F+ ++Q + D ++++ AF+++D D+ G IS L +V K + G NL D +L Sbjct: 84 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-GENLTDEEL 142 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 Q+++D+ AD+DGDG +S +EF ++ ++ Sbjct: 143 QEMIDE----ADRDGDGEVSEQEFLRIMKKTSLY 172 >1LKJ-A nrPDB Length = 146 Score = 116 bits (290), Expect = 6e-27, Method: Composition-based stats. Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 10/152 (6%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQR---VIDIFDTDGN 67 S+ ++I + F D DN+GS+S E + + L +P +++ D DGN Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 60 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 +++F EF+ +S+ D EQ+L AF+++D + DG IS EL VL + G L D Sbjct: 61 HQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI-GEKLTDA 119 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 ++ ++ + DG G I+ ++F A++ Sbjct: 120 EVDDMLREV-----SDGSGEINIQQFAALLSK 146 >3QRX-A nrPDB Length = 169 Score = 115 bits (289), Expect = 8e-27, Method: Composition-based stats. Identities = 40/153 (26%), Positives = 79/153 (51%), Gaps = 9/153 (5%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL---VQRVIDIFDTDGNGEV 70 ++ + + + F D D SG++ +E ++ L P ++++I D DG+G + Sbjct: 22 LTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTI 81 Query: 71 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ 130 DF+EF+ ++ + D +++ AFR++D D G I+ +L +V K + G NL + +LQ Sbjct: 82 DFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKEL-GENLTEEELQ 140 Query: 131 QIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 + I AD++ D I +EF ++ + Sbjct: 141 E----MIAEADRNDDNEIDEDEFIRIMKKTSLF 169 Score = 61.1 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 5/80 (6%) Query: 80 SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIIN 139 + + +++Q++R AF ++D D G I EL ++ + K+ + K I Sbjct: 18 GRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEE-----IKKMISE 72 Query: 140 ADKDGDGRISFEEFCAVVGG 159 DKDG G I FEEF ++ Sbjct: 73 IDKDGSGTIDFEEFLTMMTA 92 >1S1E-A nrPDB Length = 224 Score = 115 bits (289), Expect = 9e-27, Method: Composition-based stats. Identities = 48/185 (25%), Positives = 89/185 (48%), Gaps = 22/185 (11%) Query: 4 EASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRV 58 E LE ++F E++ L + FK + SG ++ E F + P + + Sbjct: 37 EGLEQLEAQTNFTKRELQVLYRGFK--NECPSGVVNEETFKQIYAQFFPHGDASTYAHYL 94 Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 + FDT G V F++F+ +S ++G +KLR+ F +YD++KDGYI+ E+ ++K Sbjct: 95 FNAFDTTQTGSVKFEDFVTALS-ILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKA 153 Query: 119 MVGNN-------LKDTQLQQIVDKTIINADKDGDGRISFEEFCA-------VVGGLDIHK 164 + LK+ +Q VD DK+ DG ++ +EF ++ L + + Sbjct: 154 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQ 213 Query: 165 KMVVD 169 ++V+ Sbjct: 214 NVMVE 218 >1S6C-A nrPDB Length = 183 Score = 115 bits (287), Expect = 1e-26, Method: Composition-based stats. Identities = 46/164 (28%), Positives = 80/164 (48%), Gaps = 15/164 (9%) Query: 4 EASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRV 58 E LE ++F E++ L + FK + SG ++ E F + P + + Sbjct: 4 EGLEQLEAQTNFTKRELQVLYRGFK--NECPSGVVNEETFKQIYAQFFPHGDASTYAHYL 61 Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 + FDT G V F++F+ +S ++G +KLR+ F +YD++KDGYI+ E+ ++K Sbjct: 62 FNAFDTTQTGSVKFEDFVTALS-ILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKA 120 Query: 119 MVGNN-------LKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 + LK+ +Q VD DK+ DG ++ +EF Sbjct: 121 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLE 164 >3LIJ-A nrPDB Length = 494 Score = 113 bits (284), Expect = 3e-26, Method: Composition-based stats. Identities = 43/167 (25%), Positives = 65/167 (38%), Gaps = 21/167 (12%) Query: 8 PLEMCSHFD-ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPEL------------QQNPL 54 L M S +E K L F+ +D + G L +E + Q Sbjct: 332 LLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESE 391 Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 V ++ D D NG +D+ EF+ + KL AF+ +D D +G IS EL Sbjct: 392 VDAILGAADFDRNGYIDYSEFVTVAMDRKSLL-SKDKLESAFQKFDQDGNGKISVDELAS 450 Query: 115 VLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 V + D + + I D + DG + FEEFC ++ L Sbjct: 451 VFGL-------DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLC 490 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 43/107 (40%), Gaps = 3/107 (2%) Query: 53 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 P + I+ N + + + ++ ++ ++L FR D + DG + EL Sbjct: 309 PSLANAIENMRKFQNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQEL 368 Query: 113 FQVLKMMVGNNLKDT---QLQQIVDKTIINADKDGDGRISFEEFCAV 156 + G + Q++ VD + AD D +G I + EF V Sbjct: 369 IDGYSKLSGEEVAVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTV 415 >3HZT-A nrPDB Length = 467 Score = 113 bits (283), Expect = 3e-26, Method: Composition-based stats. Identities = 42/172 (24%), Positives = 71/172 (41%), Gaps = 24/172 (13%) Query: 9 LEMCSHFDA-DEIKRLGKRFKKLDLDNSGSLSVEEFM---------------SLPELQQN 52 L M S +E K L + F++LD + G L +E + L Q Sbjct: 301 LFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIE 360 Query: 53 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 V ++ D D NG +++ EF+ + ++L AF+ +D D G I+N EL Sbjct: 361 AEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLL-SRERLLAAFQQFDSDGSGKITNEEL 419 Query: 113 FQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHK 164 ++ + + D Q + DK+ DG + FEEF ++ + K Sbjct: 420 GRLFGV---TEVDDETWHQ----VLQECDKNNDGEVDFEEFVEMMQKICDVK 464 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV------GNNLKDTQL 129 + + ++ ++L FR D + DG + EL + + ++ ++L +Q+ Sbjct: 300 MLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQI 359 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAV 156 + VD + + D D +G I + EF V Sbjct: 360 EAEVDHILQSVDFDRNGYIEYSEFVTV 386 Score = 31.5 bits (70), Expect = 0.18, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 23/45 (51%) Query: 108 SNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 S+ +L Q + +G+ L + + + + D +GDG++ +E Sbjct: 291 SSQKLAQAAMLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKE 335 >2R2I-A nrPDB Length = 198 Score = 112 bits (281), Expect = 6e-26, Method: Composition-based stats. Identities = 45/160 (28%), Positives = 80/160 (50%), Gaps = 10/160 (6%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQ-----QNPLVQRVIDIFDT 64 + A E + K+F SG L++ EF L+ N V+++ + FD Sbjct: 6 KAVEELSATECHQWYKKFMT--ECPSGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDF 63 Query: 65 DGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNL 124 + +G +DF E++ +S +KG +QKLR+ F++YD+D +G I GEL ++K + N Sbjct: 64 NKDGYIDFMEYVAALS-LVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINR 122 Query: 125 KDTQL--QQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 + + ++ + D +GDG +S EEF V ++ Sbjct: 123 CNEAMTAEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEV 162 >3KF9-A nrPDB Length = 149 Score = 112 bits (280), Expect = 9e-26, Method: Composition-based stats. Identities = 44/153 (28%), Positives = 86/153 (56%), Gaps = 9/153 (5%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL---VQRVIDIFDTDGNGEV 70 ++ + + + F D D SG++ +E ++ L P ++++I D DG+G + Sbjct: 2 LTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTI 61 Query: 71 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ 130 DF+EF++ ++ + D +++ AFR++D D+ G IS L +V K + G N+ D +LQ Sbjct: 62 DFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKEL-GENMTDEELQ 120 Query: 131 QIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 +++D+ AD+DGDG ++ EEF ++ + Sbjct: 121 EMIDE----ADRDGDGEVNEEEFFRIMKKTSLF 149 >2ZFD-A nrPDB Length = 226 Score = 111 bits (277), Expect = 2e-25, Method: Composition-based stats. Identities = 53/164 (32%), Positives = 86/164 (52%), Gaps = 8/164 (4%) Query: 2 GNEASYPLEMCSHFDADEIKRLGKRFKKLDL--DNSGSLSVEEFM---SLPELQQNPLVQ 56 G L + F EI+ L + FKK+ + G ++ EEF +++ Sbjct: 29 GLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFAD 88 Query: 57 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL 116 RV D+FDT NG + F+EF +S F + K+ F+F++YD+ + G+I E+ Q++ Sbjct: 89 RVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 Query: 117 KMMV---GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + G NLKDT ++ I+DKT AD DG+I EE+ ++V Sbjct: 149 VATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 Score = 26.8 bits (58), Expect = 4.3, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 21/55 (38%), Gaps = 6/55 (10%) Query: 104 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 DG I+ E + N K++ D+ D +G + FEEF + Sbjct: 64 DGLINKEEFQ---LALFKTNKKESL---FADRVFDLFDTKHNGILGFEEFARALS 112 >5JN2-A nrPDB Length = 525 Score = 111 bits (277), Expect = 2e-25, Method: Composition-based stats. Identities = 46/170 (27%), Positives = 73/170 (42%), Gaps = 24/170 (14%) Query: 8 PLEMCSHFD-ADEIKRLGKRFKKLDLDNSGSLS-------VEEFMSLPELQQNPL----- 54 L M S DE K L F K+D + G L +E M + + L Sbjct: 362 LLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAV 421 Query: 55 ---VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGE 111 V +V+D D D NG +++ EF+ ++L AFR++D D G IS+ E Sbjct: 422 EHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLL-SRERLERAFRMFDSDNSGKISSTE 480 Query: 112 LFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 L + G + D++ + V + DK+ DG + F+EF ++ L Sbjct: 481 LATIF----GVSDVDSETWKSV---LSEVDKNNDGEVDFDEFQQMLLKLC 523 Score = 30.7 bits (68), Expect = 0.33, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 19/44 (43%) Query: 109 NGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 +L Q + +G+ L + + DK+GDG++ E Sbjct: 354 TQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAE 397 >3Q5I-A nrPDB Length = 504 Score = 110 bits (276), Expect = 3e-25, Method: Composition-based stats. Identities = 41/161 (25%), Positives = 72/161 (44%), Gaps = 20/161 (12%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN------------PLVQRVIDIFD 63 +E K L FKKLD + G L +E + + +N V ++ D Sbjct: 350 TLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVD 409 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNN 123 D NG +++ EFI + E++LR AF ++D DK G I+ EL + + Sbjct: 410 FDKNGYIEYSEFISVCMDKQILF-SEERLRRAFNLFDTDKSGKITKEELANLFGLT---- 464 Query: 124 LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHK 164 + ++ + + AD++ D I F+EF +++ + HK Sbjct: 465 ---SISEKTWNDVLGEADQNKDNMIDFDEFVSMMHKICDHK 502 Score = 48.8 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ---VLKMMVGNNLKDTQLQQI 132 I + ++ ++L F+ D + DG + EL + VL+ + +++ Sbjct: 341 ILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEE 400 Query: 133 VDKTIINADKDGDGRISFEEFCAV 156 VD + D D +G I + EF +V Sbjct: 401 VDNILKEVDFDKNGYIEYSEFISV 424 Score = 31.1 bits (69), Expect = 0.22, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 21/41 (51%) Query: 112 LFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 L Q + +G+ L + ++ + DK+GDG++ +E Sbjct: 336 LAQAAILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKE 376 >3PM8-A nrPDB Length = 197 Score = 110 bits (276), Expect = 3e-25, Method: Composition-based stats. Identities = 39/153 (25%), Positives = 74/153 (48%), Gaps = 8/153 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEE----FMSLPELQQNPLVQRVIDIFDTDG 66 + H EI L F LD+DNSG+LS +E + + P + +V+ D++ Sbjct: 47 IAKHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNA 106 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 +G++ + +F+ KE L F+ +D+D +G IS EL ++ +++++ Sbjct: 107 SGQIHYTDFLAATIDKQTYLKKEVCL-IPFKFFDIDGNGKISVEELKRIFGR---DDIEN 162 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + + +D + D +GDG I F EF ++ Sbjct: 163 PLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSK 195 Score = 47.6 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 6/63 (9%) Query: 27 FKKLDLDNSGSLSVEEFMSLPELQ--QNPLVQRVID----IFDTDGNGEVDFKEFIEGVS 80 FK D+D +G +SVEE + +NPL+ + ID D +G+GE+DF EF+ +S Sbjct: 135 FKFFDIDGNGKISVEELKRIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMS 194 Query: 81 QFS 83 + Sbjct: 195 KKK 197 >2TN4-A nrPDB Length = 159 Score = 110 bits (274), Expect = 4e-25, Method: Composition-based stats. Identities = 48/158 (30%), Positives = 83/158 (52%), Gaps = 12/158 (7%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQR---VIDIFDTD 65 E S+ + I F D D G +SV+E + + L Q P + +I+ D D Sbjct: 6 EARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDED 65 Query: 66 GNGEVDFKEFIEGVSQFSV---KGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 G+G +DF+EF+ + + KG E++L FRI+D + DGYI EL ++ + G Sbjct: 66 GSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRA-SGE 124 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 ++ D +++ ++ + DK+ DGRI F+EF ++ G+ Sbjct: 125 HVTDEEIESLMK----DGDKNNDGRIDFDEFLKMMEGV 158 Score = 53.4 bits (127), Expect = 4e-08, Method: Composition-based stats. Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 5/81 (6%) Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKT 136 + ++ + + + + AF ++D D G IS EL V++M L T ++ +D Sbjct: 4 QAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRM-----LGQTPTKEELDAI 58 Query: 137 IINADKDGDGRISFEEFCAVV 157 I D+DG G I FEEF ++ Sbjct: 59 IEEVDEDGSGTIDFEEFLVMM 79 >4RGJ-A nrPDB Length = 520 Score = 108 bits (271), Expect = 1e-24, Method: Composition-based stats. Identities = 44/172 (25%), Positives = 73/172 (42%), Gaps = 24/172 (13%) Query: 8 PLEMCSHFDA-DEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPL-------- 54 L M S DE K L K FKK+D + G L E L +L+ Sbjct: 357 LLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAI 416 Query: 55 ---VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGE 111 V ++++ D D NG +++ EF+ + E +L AF+++D D G IS E Sbjct: 417 EYEVDQILNSIDLDQNGYIEYSEFLTVSIDRKLLLSTE-RLEKAFKLFDKDGSGKISANE 475 Query: 112 LFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 L Q+ + ++ + + D++ DG I F+EF ++ L + Sbjct: 476 LAQLFGLSDVSS-------ECWKTVLKEVDQNNDGEIDFKEFRDMLVKLCNY 520 Score = 31.8 bits (71), Expect = 0.14, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 21/45 (46%) Query: 108 SNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 S +L Q + +G+ L + + K DK+GDG++ E Sbjct: 348 STQKLAQAALLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNE 392 >2NA0-A nrPDB Length = 205 Score = 108 bits (270), Expect = 1e-24, Method: Composition-based stats. Identities = 43/158 (27%), Positives = 74/158 (46%), Gaps = 11/158 (6%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQ-----QNPLVQRVIDIFDT 64 + + E + K+F SG L++ EF L+ + V+++ + FD Sbjct: 8 KSVEELSSTECHQWYKKFMT--ECPSGQLTLYEFRQFFGLKNLSPWASQYVEQMFETFDF 65 Query: 65 DGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNL 124 + +G +DF E+ +S +KG EQKLR+ F++YD+D +G I EL +++ + N Sbjct: 66 NKDGYIDFMEYEAALS-LVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRAINP 124 Query: 125 KDTQL---QQIVDKTIINADKDGDGRISFEEFCAVVGG 159 ++ D D +GDG +S EEF V Sbjct: 125 CSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQK 162 Score = 42.2 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 41/100 (41%), Gaps = 14/100 (14%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMSL------------PELQQNPLVQRVIDIFDTD 65 ++ R FK D+D +G + +E +++ + V D + Sbjct: 89 EQKLRWY--FKLYDVDGNGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVN 146 Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDG 105 G+GE+ +EF+EGV + + D + RI ++G Sbjct: 147 GDGELSLEEFMEGVQKDQMLLDTLTRSLDLTRIVRRLQNG 186 >1TOP-A nrPDB Length = 162 Score = 108 bits (270), Expect = 1e-24, Method: Composition-based stats. Identities = 45/158 (28%), Positives = 81/158 (51%), Gaps = 12/158 (7%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQR---VIDIFDTD 65 E + + I F D D G +S +E + + L QNP + +I+ D D Sbjct: 9 EARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDED 68 Query: 66 GNGEVDFKEFIEGVSQFSV---KGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 G+G +DF+EF+ + + KG E++L FRI+D + DG+I EL ++L+ Sbjct: 69 GSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRAT--- 125 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 + ++ ++ + ++DK+ DGRI F+EF ++ G+ Sbjct: 126 --GEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMMEGV 161 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 5/81 (6%) Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKT 136 + ++ + + + + AF ++D D G IS EL V++ M+G N +L D Sbjct: 7 QAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMR-MLGQNPTKEEL----DAI 61 Query: 137 IINADKDGDGRISFEEFCAVV 157 I D+DG G I FEEF ++ Sbjct: 62 IEEVDEDGSGTIDFEEFLVMM 82 >6EPA-A nrPDB Length = 187 Score = 108 bits (270), Expect = 1e-24, Method: Composition-based stats. Identities = 50/172 (29%), Positives = 89/172 (51%), Gaps = 21/172 (12%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFD 63 L ++F EI++ K F L +G L+ + F+ + P+ + V +FD Sbjct: 16 LTTDTYFTEKEIRQWHKGF--LKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFD 73 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MV 120 + +G ++F+EFI +S + +G+ ++KL +AFR+YD+D DGYI+ E++ ++ MV Sbjct: 74 ENNDGAIEFEEFIRALS-ITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMV 132 Query: 121 GNNLK---DTQLQQIVDKTIINADKDGDGRISFEEF-------CAVVGGLDI 162 G + + Q+ VDK DK+ D R++ EEF +V L + Sbjct: 133 GQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSL 184 >1UHN-A nrPDB Length = 189 Score = 108 bits (269), Expect = 2e-24, Method: Composition-based stats. Identities = 52/161 (32%), Positives = 85/161 (52%), Gaps = 8/161 (4%) Query: 5 ASYPLEMCSHFDADEIKRLGKRFKKLDL--DNSGSLSVEEFM---SLPELQQNPLVQRVI 59 L + F EI+ L + FKK+ + G ++ EEF +++ RV Sbjct: 1 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF 60 Query: 60 DIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM 119 D+FDT NG + F+EF +S F + K+ F+F++YD+ + G+I E+ Q++ Sbjct: 61 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 120 Query: 120 V---GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + G NLKDT ++ I+DKT AD DG+I EE+ ++V Sbjct: 121 LAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 161 Score = 26.1 bits (56), Expect = 7.4, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 19/55 (34%), Gaps = 6/55 (10%) Query: 104 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 DG I+ E + + + D+ D +G + FEEF + Sbjct: 33 DGLINKEEFQ------LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALS 81 >4WPX-A nrPDB Length = 177 Score = 108 bits (269), Expect = 2e-24, Method: Composition-based stats. Identities = 42/167 (25%), Positives = 78/167 (46%), Gaps = 23/167 (13%) Query: 8 PLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM--------SLPELQQNPLV---- 55 P E + ++ R+ + F+ D + G LS EEF LP+ Q ++ Sbjct: 13 PREDYNKLSDEQKTRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHG 72 Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQ-----FSVKGDKEQKLRFAFRIYDMDKDGYISNG 110 QR + + D +++F +Q + D +LR AFR++D+D G I+ Sbjct: 73 QRPAN-WPHDQECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITED 131 Query: 111 ELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 +L +V + VGNN+ D +Q ++++ D +G G + +EF ++ Sbjct: 132 DLRKVCQQ-VGNNIPDADIQAMIEEF----DSNGKGGVDEDEFLRLM 173 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 1/39 (2%) Query: 122 NNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 N L D Q + + + D + DG +S+EEF V+ L Sbjct: 18 NKLSDEQ-KTRISEAFELFDSNKDGLLSYEEFRFVLRAL 55 >2AAO-A nrPDB Length = 166 Score = 107 bits (268), Expect = 2e-24, Method: Composition-based stats. Identities = 44/159 (27%), Positives = 75/159 (47%), Gaps = 12/159 (7%) Query: 8 PLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIF---D 63 + +EI L + F +D D SG ++ EE + L + N ++D+ D Sbjct: 14 LRVIAESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAAD 73 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNN 123 D +G +D+KEFI + K ++E L AF +D D GYI+ EL Q + + Sbjct: 74 VDNSGTIDYKEFIAATLHLN-KIEREDHLFAAFTYFDKDGSGYITPDELQQACEEFGVED 132 Query: 124 LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 + +++ + + D+D DGRI + EF A++ I Sbjct: 133 V-------RIEELMRDVDQDNDGRIDYNEFVAMMQKGSI 164 Score = 47.6 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 8/87 (9%) Query: 72 FKEFIEGVSQFSVKGDKEQK---LRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQ 128 +F + + + E++ L+ F + D DK G I+ EL LK VG NLK+++ Sbjct: 6 MNKFKKMALRVIAESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKR-VGANLKESE 64 Query: 129 LQQIVDKTIINADKDGDGRISFEEFCA 155 + ++ AD D G I ++EF A Sbjct: 65 ILDLM----QAADVDNSGTIDYKEFIA 87 Score = 43.0 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPE--LQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVS 80 L F D D SG ++ +E E ++ ++ ++ D D +G +D+ EF+ + Sbjct: 101 LFAAFTYFDKDGSGYITPDELQQACEEFGVEDVRIEELMRDVDQDNDGRIDYNEFVAMMQ 160 Query: 81 QFSVKG 86 + S+ G Sbjct: 161 KGSITG 166 Score = 27.6 bits (60), Expect = 2.7, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 20/50 (40%) Query: 2 GNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQ 51 G L+ E R+ + + +D DN G + EF+++ + Sbjct: 114 GYITPDELQQACEEFGVEDVRIEELMRDVDQDNDGRIDYNEFVAMMQKGS 163 >4YZB-A nrPDB Length = 491 Score = 106 bits (266), Expect = 3e-24, Method: Composition-based stats. Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 24/170 (14%) Query: 8 PLEMCSHFD-ADEIKRLGKRFKKLDLDNSGSLSVEEFMS----LPELQQNPL-------- 54 L M S +E L K F+++D + G L +E M L +L+ + Sbjct: 325 LLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAI 384 Query: 55 ---VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGE 111 V++V+D D D NG +++ EF+ Q+L AF ++D D G IS+ E Sbjct: 385 EFEVEQVLDAVDFDKNGFIEYSEFVTVAMDRKTLL-SRQRLERAFGMFDADGSGKISSSE 443 Query: 112 LFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 L + + ++ + + + D++ DG + FEEF ++ L Sbjct: 444 LATIFGVSEVDS-------ETWRRVLAEVDRNNDGEVDFEEFRQMLLKLC 486 Score = 31.8 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 21/44 (47%) Query: 109 NGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 +L + +G+ L + ++K DK+GDG++ +E Sbjct: 317 TQKLAAAALLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQE 360 >3NCG-A nrPDB Length = 486 Score = 106 bits (265), Expect = 5e-24, Method: Composition-based stats. Identities = 46/170 (27%), Positives = 81/170 (47%), Gaps = 25/170 (14%) Query: 8 PLEMCSHFDA-DEIKRLGKRFKKLDLDNSGSLS-------VEEFMSLPELQQNPLVQ--- 56 L M S DE K+L + F+KLD +N G L EFM L + N L+Q Sbjct: 317 LLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEG 376 Query: 57 --------RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYIS 108 ++ + D DG+G +++ EFI ++ +++ AF+++D D G IS Sbjct: 377 STIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILL-SRERMERAFKMFDKDGSGKIS 435 Query: 109 NGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 ELF++ + ++ +L+ I+++ D + DG + F EF ++ Sbjct: 436 TKELFKLFSQADSS-IQMEELESIIEQV----DNNKDGEVDFNEFVEMLQ 480 Score = 53.8 bits (128), Expect = 3e-08, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 4/70 (5%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQ----QNPLVQRVIDIFDTDGNGEVDFKEFI 76 +R+ + FK D D SG +S +E L Q ++ +I+ D + +GEVDF EF+ Sbjct: 417 ERMERAFKMFDKDGSGKISTKELFKLFSQADSSIQMEELESIIEQVDNNKDGEVDFNEFV 476 Query: 77 EGVSQFSVKG 86 E + F Sbjct: 477 EMLQNFVRNE 486 Score = 28.0 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 7/47 (14%), Positives = 17/47 (36%) Query: 109 NGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 +L Q + + + L + + + D + DG + +E Sbjct: 309 EKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVR 355 >3L19-A nrPDB Length = 214 Score = 105 bits (262), Expect = 1e-23, Method: Composition-based stats. Identities = 43/167 (25%), Positives = 65/167 (38%), Gaps = 21/167 (12%) Query: 8 PLEMCSHFD-ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPEL------------QQNPL 54 L M S +E K L F+ +D + G L +E + Q Sbjct: 49 LLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESE 108 Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 V ++ D D NG +D+ EF+ + KL AF+ +D D +G IS EL Sbjct: 109 VDAILGAADFDRNGYIDYSEFVTVAMDRKSLL-SKDKLESAFQKFDQDGNGKISVDELAS 167 Query: 115 VLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 V + D + + I D + DG + FEEFC ++ L Sbjct: 168 VFGL-------DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLC 207 Score = 48.8 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 39/70 (55%), Gaps = 2/70 (2%) Query: 22 RLGKRFKKLDLDNSGSLSVEEFMSLPELQ--QNPLVQRVIDIFDTDGNGEVDFKEFIEGV 79 +L F+K D D +G +SV+E S+ L ++ + +I D++ +G+VDF+EF + + Sbjct: 144 KLESAFQKFDQDGNGKISVDELASVFGLDHLESKTWKEMISGIDSNNDGDVDFEEFCKMI 203 Query: 80 SQFSVKGDKE 89 + + + Sbjct: 204 QKLCSNNEPQ 213 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 43/107 (40%), Gaps = 3/107 (2%) Query: 53 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 P + I+ N + + + ++ ++ ++L FR D + DG + EL Sbjct: 26 PSLANAIENMRKFQNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQEL 85 Query: 113 FQVLKMMVGNNLKDT---QLQQIVDKTIINADKDGDGRISFEEFCAV 156 + G + Q++ VD + AD D +G I + EF V Sbjct: 86 IDGYSKLSGEEVAVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTV 132 >1JBA-A nrPDB Length = 204 Score = 105 bits (262), Expect = 1e-23, Method: Composition-based stats. Identities = 44/156 (28%), Positives = 81/156 (51%), Gaps = 19/156 (12%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNP----LVQRVIDIFDTDGNGEVD 71 DA +++ K+F L+ SG+L + EF ++ N V+ + FDT+G+ +D Sbjct: 20 DAAQLQEWYKKF--LEECPSGTLFMHEFKRFFKVPDNEEATQYVEAMFRAFDTNGDNTID 77 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV------LKMMVGNNLK 125 F E++ ++ ++G E KL++ F+IYD D++G I EL + LK ++ Sbjct: 78 FLEYVAALN-LVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEVE 136 Query: 126 DTQ------LQQIVDKTIINADKDGDGRISFEEFCA 155 Q +++VD+ + D++GDG++S EF Sbjct: 137 AEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVE 172 Score = 36.8 bits (84), Expect = 0.004, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 33/81 (40%), Gaps = 21/81 (25%) Query: 22 RLGKRFKKLDLDNSGSLSVEEFMSLPE---------------------LQQNPLVQRVID 60 +L FK D D +G + +E + + E L +V R+ Sbjct: 96 KLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFL 155 Query: 61 IFDTDGNGEVDFKEFIEGVSQ 81 + D +G+G++ EF+EG + Sbjct: 156 LVDENGDGQLSLNEFVEGARR 176 >2OBH-A nrPDB Length = 143 Score = 105 bits (262), Expect = 1e-23, Method: Composition-based stats. Identities = 42/148 (28%), Positives = 86/148 (58%), Gaps = 9/148 (6%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL---VQRVIDIFDTDGNGEVD 71 ++ + + + F D D +G++ V+E ++ L P ++++I D +G G+++ Sbjct: 1 TEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMN 60 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 F +F+ ++Q + D ++++ AF+++D D+ G IS L +V K + G NL D +LQ+ Sbjct: 61 FGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-GENLTDEELQE 119 Query: 132 IVDKTIINADKDGDGRISFEEFCAVVGG 159 ++D+ AD+DGDG +S +EF ++ Sbjct: 120 MIDE----ADRDGDGEVSEQEFLRIMKK 143 >3FWC-A nrPDB Length = 161 Score = 103 bits (257), Expect = 4e-23, Method: Composition-based stats. Identities = 39/151 (25%), Positives = 75/151 (49%), Gaps = 9/151 (5%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQR----VIDIFDTD 65 + S ++ + + + F D++N G L E + L +R +ID +D++ Sbjct: 12 PLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSE 71 Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 G + + +F + + +K D +++ AF+++D D G IS L +V K + G L Sbjct: 72 GRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKEL-GETLT 130 Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEFCAV 156 D +L+ ++++ D DGDG I+ EF A+ Sbjct: 131 DEELRAMIEEF----DLDGDGEINENEFIAI 157 Score = 41.1 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 40/85 (47%), Gaps = 4/85 (4%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQ 56 M + Y + D + + + F+ D D++G +S++ L E + ++ Sbjct: 76 MKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELR 135 Query: 57 RVIDIFDTDGNGEVDFKEFIEGVSQ 81 +I+ FD DG+GE++ EFI + Sbjct: 136 AMIEEFDLDGDGEINENEFIAICTD 160 >2GGZ-A nrPDB Length = 211 Score = 103 bits (256), Expect = 5e-23, Method: Composition-based stats. Identities = 42/147 (28%), Positives = 69/147 (46%), Gaps = 9/147 (6%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQ-----QNPLVQRVIDIFDTDGNGEVDFK 73 E + F SG ++ EF +L LQ N + +V + FDT+ +G VDF Sbjct: 20 ETHVWYRTFMM--EYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 77 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT-QLQQI 132 EFI V+ + EQKL++ F++YD D +G I EL + + N + T ++ Sbjct: 78 EFIAAVNLIM-QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEF 136 Query: 133 VDKTIINADKDGDGRISFEEFCAVVGG 159 ++ D + DG ++ EEF + Sbjct: 137 INLVFHKIDINNDGELTLEEFINGMAK 163 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 36/94 (38%), Gaps = 5/94 (5%) Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 +G EF + + + + + +D +KDG++ E + +++ Sbjct: 34 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM-----Q 88 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 +++Q + D DG+G I E + + Sbjct: 89 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV 122 Score = 29.5 bits (65), Expect = 0.78, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 3/58 (5%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDG 66 L +E L F K+D++N G L++EEF++ Q L++ V FD Sbjct: 125 LNGQQTLSPEEFINL--VFHKIDINNDGELTLEEFINGMAKDQ-DLLEIVYKSFDFSN 179 >1S6I-A nrPDB Length = 188 Score = 103 bits (256), Expect = 6e-23, Method: Composition-based stats. Identities = 43/152 (28%), Positives = 75/152 (49%), Gaps = 12/152 (7%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGN 67 +EI L + FK +D DNSG+++ +E + + L ++ ++D D D + Sbjct: 1 AERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKS 60 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 G +D+ EFI + K ++E+ L AF +D D GYI+ E+ Q K +++ Sbjct: 61 GTIDYGEFIAATVHLN-KLEREENLVSAFSYFDKDGSGYITLDEIQQACKDFGLDDI--- 116 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 +D I D+D DG+I + EF A++ Sbjct: 117 ----HIDDMIKEIDQDNDGQIDYGEFAAMMRK 144 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 20/123 (16%), Positives = 43/123 (34%), Gaps = 21/123 (17%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMSLPE--LQQNPLVQRVIDIFDTDGNGEVDFKEF 75 + + L F D D SG ++++E + + + +I D D +G++D+ EF Sbjct: 79 EREENLVSAFSYFDKDGSGYITLDEIQQACKDFGLDDIHIDDMIKEIDQDNDGQIDYGEF 138 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDK 135 + + +G I + + L + L D Q+++ Sbjct: 139 AAMMRKRK-------------------GNGGIGRRTMRKTLNLRDALGLVDNGSNQVIEG 179 Query: 136 TII 138 Sbjct: 180 YFK 182 >2LHH-A nrPDB Length = 128 Score = 102 bits (254), Expect = 9e-23, Method: Composition-based stats. Identities = 39/123 (31%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQR---VIDIFDTDGN 67 S+ ++I + F D DN+GS+S E + + L +P +++ D DGN Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 60 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 +++F EF+ +S+ D EQ+L AF+++D + DG IS EL VL + G L D Sbjct: 61 HQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI-GEKLTDA 119 Query: 128 QLQ 130 +L+ Sbjct: 120 ELE 122 Score = 53.0 bits (126), Expect = 6e-08, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 5/69 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF ++D D +G IS+ EL V++ + G + + + V+ + D DG+ +I F Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSL-GLSPSEAE----VNDLMNEIDVDGNHQIEF 65 Query: 151 EEFCAVVGG 159 EF A++ Sbjct: 66 SEFLALMSR 74 >3KHE-A nrPDB Length = 191 Score = 102 bits (254), Expect = 9e-23, Method: Composition-based stats. Identities = 40/172 (23%), Positives = 70/172 (40%), Gaps = 24/172 (13%) Query: 9 LEMCSHFDA-DEIKRLGKRFKKLDLDNSGSLSVEEFM---------------SLPELQQN 52 L M S +E K L + F++LD + G L +E + L Q Sbjct: 27 LFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIE 86 Query: 53 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 V ++ D D NG +++ EF+ + ++L AF+ +D D G I+N EL Sbjct: 87 AEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLL-SRERLLAAFQQFDSDGSGKITNEEL 145 Query: 113 FQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHK 164 ++ + + + + DK+ DG + FEEF ++ + K Sbjct: 146 GRLFGVT-------EVDDETWHQVLQECDKNNDGEVDFEEFVEMMQKICDVK 190 Score = 44.9 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV------GNNLKDTQL 129 + + ++ ++L FR D + DG + EL + + ++ ++L +Q+ Sbjct: 26 MLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQI 85 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAV 156 + VD + + D D +G I + EF V Sbjct: 86 EAEVDHILQSVDFDRNGYIEYSEFVTV 112 Score = 29.1 bits (64), Expect = 0.84, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 23/45 (51%) Query: 108 SNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 S+ +L Q + +G+ L + + + + D +GDG++ +E Sbjct: 17 SSQKLAQAAMLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKE 61 >2I94-A nrPDB Length = 202 Score = 101 bits (252), Expect = 1e-22, Method: Composition-based stats. Identities = 39/169 (23%), Positives = 75/169 (44%), Gaps = 17/169 (10%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLV 55 + E L++ + F +E+ + F L SG ++ +EF ++ PE Sbjct: 9 LSKEILEELQLNTKFTEEELSSWYQSF--LKECPSGRITRQEFQTIYSKFFPEADPKAYA 66 Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 Q V FD + +G +DFKE++ + + G QKL +AF +YD+D +G IS E+ ++ Sbjct: 67 QHVFRSFDANSDGTLDFKEYVIAL-HMTSAGKTNQKLEWAFSLYDVDGNGTISKNEVLEI 125 Query: 116 LKMM---------VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 + + + ++ +K K D +++ +EF Sbjct: 126 VTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIE 174 Score = 34.9 bits (79), Expect = 0.017, Method: Composition-based stats. Identities = 10/75 (13%), Positives = 27/75 (36%), Gaps = 5/75 (6%) Query: 88 KEQKLRFAFRIYDMD-KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 E++L ++ + + G I+ E + + + + + D + DG Sbjct: 24 TEEELSSWYQSFLKECPSGRITRQE----FQTIYSKFFPEADPKAYAQHVFRSFDANSDG 79 Query: 147 RISFEEFCAVVGGLD 161 + F+E+ + Sbjct: 80 TLDFKEYVIALHMTS 94 >3O4Y-A nrPDB Length = 196 Score = 100 bits (249), Expect = 4e-22, Method: Composition-based stats. Identities = 42/144 (29%), Positives = 73/144 (50%), Gaps = 7/144 (4%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPE---LQQNPLVQRVIDIFDTDGNGEVDFKEF 75 ++++L F LD + G+++ + E L P ++D D+DG+G +D+ EF Sbjct: 53 DVQKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNFDLLLDQIDSDGSGNIDYTEF 112 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL-KMMVGNNLKDTQLQQIVD 134 + + ++ + AFR++D+D DG I+ EL VL N+ + + Q V Sbjct: 113 LAAAID--RRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNGNKRGNITERDVNQ-VK 169 Query: 135 KTIINADKDGDGRISFEEFCAVVG 158 K I DK+GDG+I F EF ++ Sbjct: 170 KMIREVDKNGDGKIDFYEFSEMMK 193 Score = 31.8 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 6/36 (16%), Positives = 18/36 (50%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPEL 49 + ++ ++ K +++D + G + EF + +L Sbjct: 159 NITERDVNQVKKMIREVDKNGDGKIDFYEFSEMMKL 194 >4JWQ-A nrPDB Length = 199 Score = 99.6 bits (247), Expect = 5e-22, Method: Composition-based stats. Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 11/146 (7%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQR---VIDIFDTDGNGEVDFKEF 75 ++++L F LD D G+++ + E L Q ++D D+DG+G +D+ EF Sbjct: 56 DLQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEF 115 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVD- 134 + K ++ + AFR++D+D DG I+ EL + + N K + Q+ V+ Sbjct: 116 LAAA--LDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHI---LYNGNKKGSITQKDVNQ 170 Query: 135 --KTIINADKDGDGRISFEEFCAVVG 158 K I DK+ DG+I F EFC ++ Sbjct: 171 VKKMIQEVDKNNDGKIDFYEFCEMMK 196 Score = 43.8 bits (102), Expect = 3e-05, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 29/69 (42%), Gaps = 9/69 (13%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNP---------LVQRVIDIFDTDGNGEVDFK 73 + F+ D+DN G ++ E + V+++I D + +G++DF Sbjct: 130 IYCAFRVFDVDNDGEITTAELAHILYNGNKKGSITQKDVNQVKKMIQEVDKNNDGKIDFY 189 Query: 74 EFIEGVSQF 82 EF E + Sbjct: 190 EFCEMMKLK 198 Score = 29.9 bits (66), Expect = 0.57, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 24/50 (48%), Gaps = 3/50 (6%) Query: 4 EASYPLEMCSH---FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQ 50 E ++ L + ++ ++ K +++D +N G + EF + +L+ Sbjct: 149 ELAHILYNGNKKGSITQKDVNQVKKMIQEVDKNNDGKIDFYEFCEMMKLK 198 >2D8N-A nrPDB Length = 207 Score = 98.9 bits (245), Expect = 9e-22, Method: Composition-based stats. Identities = 40/169 (23%), Positives = 81/169 (47%), Gaps = 17/169 (10%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNPLV 55 + E L++ + F +E+ + F L +G ++ ++F S+ P+ Sbjct: 16 LSKEILEELQLNTKFSEEELCSWYQSF--LKDCPTGRITQQQFQSIYAKFFPDTDPKAYA 73 Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ- 114 Q V FD++ +G +DFKE++ + + G QKL +AF +YD+D +G IS E+ + Sbjct: 74 QHVFRSFDSNLDGTLDFKEYVIAL-HMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEI 132 Query: 115 ---VLKMMVGNNLK-----DTQLQQIVDKTIINADKDGDGRISFEEFCA 155 + KM+ ++K + ++ +K K+ D +++ +EF Sbjct: 133 VMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIE 181 Score = 32.2 bits (72), Expect = 0.100, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 28/72 (38%), Gaps = 5/72 (6%) Query: 88 KEQKLRFAFRIYDMD-KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 E++L ++ + D G I+ Q + + DT + + D + DG Sbjct: 31 SEEELCSWYQSFLKDCPTGRIT----QQQFQSIYAKFFPDTDPKAYAQHVFRSFDSNLDG 86 Query: 147 RISFEEFCAVVG 158 + F+E+ + Sbjct: 87 TLDFKEYVIALH 98 >2JNF-A nrPDB Length = 158 Score = 97.7 bits (242), Expect = 2e-21, Method: Composition-based stats. Identities = 47/160 (29%), Positives = 80/160 (50%), Gaps = 14/160 (8%) Query: 11 MCSHFDADEIKRLGKRFKKLDL-DNSGSLSVEEFMSLPEL----QQNPLVQRVIDIFDTD 65 S ++++K L F+ + + SG +S ++ + E+ Q ++++ID FD Sbjct: 3 DVSKLSSNQVKLLETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLIDEFDPF 62 Query: 66 GNGEVDFKEF----IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVG 121 GNG++DF F + + +Q+LR AFR+YD + +GYIS + ++L Sbjct: 63 GNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILA---- 118 Query: 122 NNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 L +T + +D I D DG G + FEEF V+ G D Sbjct: 119 -ELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVMTGGD 157 >2M29-A nrPDB Length = 171 Score = 97.3 bits (241), Expect = 3e-21, Method: Composition-based stats. Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 12/141 (8%) Query: 26 RFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIFDTDG---NGEVDFKEFIEGVSQ 81 F++ D D G + E + L P ++++ G VDF+EF+E +S Sbjct: 33 AFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELISP 92 Query: 82 FSVKGDKE----QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTI 137 + ++LR AFR +D D+DG I+ EL Q ++G L+ T+L D+ + Sbjct: 93 KLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTEL----DEML 148 Query: 138 INADKDGDGRISFEEFCAVVG 158 D +GDG I F+EF ++ Sbjct: 149 REMDLNGDGTIDFDEFVMMLS 169 Score = 27.2 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 7/32 (21%), Positives = 17/32 (53%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQ 50 E L + +++DL+ G++ +EF+ + Sbjct: 140 EGTELDEMLREMDLNGDGTIDFDEFVMMLSTG 171 >3K21-A nrPDB Length = 191 Score = 97.3 bits (241), Expect = 3e-21, Method: Composition-based stats. Identities = 41/144 (28%), Positives = 72/144 (50%), Gaps = 7/144 (4%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPE---LQQNPLVQRVIDIFDTDGNGEVDFKEF 75 ++++L F LD D G ++ E+ E L+ ++D D+DG+G++D+ EF Sbjct: 50 DVEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEF 109 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL-KMMVGNNLKDTQLQQIVD 134 I K ++ + AFR++D+D DG I+ EL +L N+ + V Sbjct: 110 IAAA--LDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGNITQRDV-NRVK 166 Query: 135 KTIINADKDGDGRISFEEFCAVVG 158 + I + DK+ DG+I F EF ++ Sbjct: 167 RMIRDVDKNNDGKIDFHEFSEMMK 190 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 35/86 (40%), Gaps = 6/86 (6%) Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 + F++ + +KL+ F + D D GYI+ +L + G +L Sbjct: 32 LKFQKLAMTIIAQQSNDYDVEKLKSTFLVLDEDGKGYITKEQLKK------GLEKDGLKL 85 Query: 130 QQIVDKTIINADKDGDGRISFEEFCA 155 D + D DG G+I + EF A Sbjct: 86 PYNFDLLLDQIDSDGSGKIDYTEFIA 111 Score = 31.1 bits (69), Expect = 0.25, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 18/36 (50%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPEL 49 + ++ R+ + + +D +N G + EF + +L Sbjct: 156 NITQRDVNRVKRMIRDVDKNNDGKIDFHEFSEMMKL 191 >5ZOR-A nrPDB Length = 149 Score = 96.9 bits (240), Expect = 3e-21, Method: Composition-based stats. Identities = 48/148 (32%), Positives = 79/148 (53%), Gaps = 13/148 (8%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPL----VQRVIDIFDTDGNGE 69 ++I + F D D SG++ EE +++ L L V+R + +T+ NG Sbjct: 4 LTDEQI---REAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGL 60 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 +++ EF V + D +++ AF+++D+DK G IS L +V K ++G N D L Sbjct: 61 IEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAK-LLGENPGDDVL 119 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVV 157 Q+ I AD+DGDG +SFEEF +V+ Sbjct: 120 QE----MIAEADEDGDGEVSFEEFKSVM 143 Score = 46.1 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 37/71 (52%), Gaps = 4/71 (5%) Query: 88 KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR 147 ++++R AF ++D D G I E+ +K + +L + V++T+ + + + +G Sbjct: 5 TDEQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDL----PRDEVERTVRSMNTNANGL 60 Query: 148 ISFEEFCAVVG 158 I + EF +V Sbjct: 61 IEYGEFERMVK 71 Score = 39.9 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN----PLVQRVIDIFDTDGNGEVDF 72 D + + K F+ DLD G +S + +L ++Q +I D DG+GEV F Sbjct: 77 KDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPGDDVLQEMIAEADEDGDGEVSF 136 Query: 73 KEFIEGVSQFSVK 85 +EF + Q K Sbjct: 137 EEFKSVMMQMRGK 149 >2LC5-A nrPDB Length = 151 Score = 95.4 bits (236), Expect = 1e-20, Method: Composition-based stats. Identities = 39/153 (25%), Positives = 78/153 (50%), Gaps = 10/153 (6%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDI---FDTD 65 E A+E + + F+ D DN L+ EE + + L NP Q++ +I +D D Sbjct: 3 EQKKVLTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKD 62 Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 +G+ D + F+ + ++ + D + ++ AF I+D +K+GYIS EL VL + G L Sbjct: 63 NSGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTTL-GEKLT 121 Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 + ++ ++ + + +G I+ ++F ++ Sbjct: 122 EQEVDDLLKEIGVE-----EGLINVDDFVKLIT 149 >1DTL-A nrPDB Length = 161 Score = 93.1 bits (230), Expect = 6e-20, Method: Composition-based stats. Identities = 46/160 (28%), Positives = 77/160 (48%), Gaps = 13/160 (8%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLD-NSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDT 64 ++ F L GS+S +E + L QNP +Q +ID D Sbjct: 7 AAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDE 66 Query: 65 DGNGEVDFKEFIEGVSQFSV---KGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVG 121 DG+G VDF EF+ + + KG E++L FR++D + DGYI EL +L+ Sbjct: 67 DGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQAT-- 124 Query: 122 NNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 +T + +++ + + DK+ DGRI ++EF + G++ Sbjct: 125 ---GETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE 161 >1DGU-A nrPDB Length = 183 Score = 92.3 bits (228), Expect = 9e-20, Method: Composition-based stats. Identities = 38/132 (28%), Positives = 71/132 (53%), Gaps = 5/132 (3%) Query: 37 SLSVEEFMSLPELQQNPLVQRVIDIFDTD-GNGEVDFKEFIEGVSQFSVKGDKEQKLRFA 95 + E+ +SLPEL+ NP +R+ +F T + F++F++ +S FS + K +A Sbjct: 44 QVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYA 103 Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGN----NLKDTQLQQIVDKTIINADKDGDGRISFE 151 FRI+D D DG ++ +L +++ + G L ++++Q++D + +D D DG I+ Sbjct: 104 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 163 Query: 152 EFCAVVGGLDIH 163 EF V+ Sbjct: 164 EFQHVISRSPDF 175 Score = 34.5 bits (78), Expect = 0.022, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 29/69 (42%), Gaps = 13/69 (18%) Query: 26 RFKKLDLDNSGSLSVEEF-------------MSLPELQQNPLVQRVIDIFDTDGNGEVDF 72 F+ D D+ G+L+ E+ L + L+ +++ D D +G ++ Sbjct: 103 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 162 Query: 73 KEFIEGVSQ 81 EF +S+ Sbjct: 163 SEFQHVISR 171 >5E37-A nrPDB Length = 356 Score = 92.3 bits (228), Expect = 9e-20, Method: Composition-based stats. Identities = 37/154 (24%), Positives = 72/154 (46%), Gaps = 18/154 (11%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN-------------PLVQRVIDIF 62 +++ L +RFK D+D +G + EE +L E ++ ++R ++ + Sbjct: 24 SKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQY 83 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 D + +G + F+EF + + + + AF+ D +G I EL ++ + GN Sbjct: 84 DVNKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASL-GN 142 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAV 156 + L+++VD + DKD G+I F EF + Sbjct: 143 PVS---LEKLVDLMQMY-DKDDSGQIEFPEFLLM 172 Score = 58.8 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 43/84 (51%), Gaps = 9/84 (10%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNL----KDTQLQQIVDKTIINADKDGD 145 ++L F++ D+D +G+I EL +L+ M + + + +++ + D + D Sbjct: 29 EELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVNKD 88 Query: 146 GRISFEEFCAVVGGLDIHKKMVVD 169 G ISFEEF ++ + ++++ Sbjct: 89 GVISFEEFKQII-----YDGLLLE 107 >2LM5-A nrPDB Length = 214 Score = 91.2 bits (225), Expect = 2e-19, Method: Composition-based stats. Identities = 38/132 (28%), Positives = 71/132 (53%), Gaps = 5/132 (3%) Query: 37 SLSVEEFMSLPELQQNPLVQRVIDIFDTD-GNGEVDFKEFIEGVSQFSVKGDKEQKLRFA 95 + E+ +SLPEL+ NP +R+ +F T + F++F++ +S FS + K +A Sbjct: 75 QVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYA 134 Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGN----NLKDTQLQQIVDKTIINADKDGDGRISFE 151 FRI+D D DG ++ +L +++ + G L ++++Q++D + +D D DG I+ Sbjct: 135 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 194 Query: 152 EFCAVVGGLDIH 163 EF V+ Sbjct: 195 EFQHVISRSPDF 206 Score = 34.2 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 29/69 (42%), Gaps = 13/69 (18%) Query: 26 RFKKLDLDNSGSLSVEEF-------------MSLPELQQNPLVQRVIDIFDTDGNGEVDF 72 F+ D D+ G+L+ E+ L + L+ +++ D D +G ++ Sbjct: 134 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 193 Query: 73 KEFIEGVSQ 81 EF +S+ Sbjct: 194 SEFQHVISR 202 >4N5X-A nrPDB Length = 199 Score = 90.8 bits (224), Expect = 3e-19, Method: Composition-based stats. Identities = 36/151 (23%), Positives = 70/151 (46%), Gaps = 15/151 (9%) Query: 7 YPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ----RVIDIF 62 + L + DA++ R F+ LD + G + + E PL Q ++ Sbjct: 8 FVLPTAASQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTG 67 Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 D + +G++DF+EF++ + D E+K++ AF+ D + DG I E+ Q L+ + G Sbjct: 68 DVNKDGKLDFEEFMKYLK------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTL-GL 120 Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 + + Q + + + D DG + + E+ Sbjct: 121 TISEQQAE----LILQSIDVDGTMTVDWNEW 147 Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 S ++ + F+ D + DG + GEL + L+ + +D + +K D Sbjct: 15 SQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE-----EKIFTTGDV 69 Query: 143 DGDGRISFEEFCAVVG 158 + DG++ FEEF + Sbjct: 70 NKDGKLDFEEFMKYLK 85 >2BL0-B nrPDB Length = 145 Score = 87.7 bits (216), Expect = 2e-18, Method: Composition-based stats. Identities = 43/149 (28%), Positives = 77/149 (51%), Gaps = 20/149 (13%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 AD+I+ F+ D DN G +S+EE S L L +NP + I G+++ KE Sbjct: 3 SADQIQEC---FQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTI-----KGQLNAKE 54 Query: 75 F----IEGVSQFSVKGDKEQ--KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQ 128 F + V + +K EQ ++ AFR D + +G I EL Q+L + G+ L ++ Sbjct: 55 FDLATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNL-GDALTSSE 113 Query: 129 LQQIVDKTIINADKDGDGRISFEEFCAVV 157 +++++ + ++ GDG I++E F ++ Sbjct: 114 VEELMKEVSVS----GDGAINYESFVDML 138 >4ZCV-A nrPDB Length = 165 Score = 85.8 bits (211), Expect = 8e-18, Method: Composition-based stats. Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 15/142 (10%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ----RVIDIFDTDGNGEVD 71 DA++ R F+ LD + G + + E PL Q ++ D + +G++D Sbjct: 8 DAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLD 67 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 F+EF++ + D E+K++ AF+ D + DG I E+ Q L+ + G + + Q + Sbjct: 68 FEEFMKYLK------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTL-GLTISEQQAE- 119 Query: 132 IVDKTIINADKDGDGRISFEEF 153 + + D DG + + E+ Sbjct: 120 ---LILQSIDVDGTMTVDWNEW 138 Score = 40.7 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 5/68 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + F+ D + DG + GEL + L+ + +D + +K D + DG++ F Sbjct: 14 RYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE-----EKIFTTGDVNKDGKLDF 68 Query: 151 EEFCAVVG 158 EEF + Sbjct: 69 EEFMKYLK 76 >2JNX-A nrPDB Length = 134 Score = 85.8 bits (211), Expect = 8e-18, Method: Composition-based stats. Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 15/138 (10%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSL----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGV 79 FK+LD + GS+S EE + ++ L+Q + D DGNGE+D EF + Sbjct: 3 EALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKFA 62 Query: 80 SQFSVKGDKEQK--LRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTI 137 + + ++K L+ +++ D D DG ++ E V K +++VD+ I Sbjct: 63 AAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEE--------VTTFFKKFGYEKVVDQ-I 113 Query: 138 INADKDGDGRISFEEFCA 155 + AD +GDG I+ EEF A Sbjct: 114 MKADANGDGYITLEEFLA 131 Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 3/106 (2%) Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113 + + + D +G+G V ++E VS EQ L+ F+ D+D +G I E Sbjct: 1 MAEALFKQLDANGDGSVSYEEVKAFVSSKRP-IKNEQLLQLIFKAIDIDGNGEIDLAEFT 59 Query: 114 QVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + + +L D ++ + D DGDG+++ EE Sbjct: 60 KFAAAVKEQDLSDEKVG--LKILYKLMDADGDGKLTKEEVTTFFKK 103 Score = 39.5 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 24/68 (35%), Gaps = 5/68 (7%) Query: 93 RFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 F+ D + DG +S E+ + +Q++ D DG+G I E Sbjct: 3 EALFKQLDANGDGSVSYEEVKAFVSSKRPIK-----NEQLLQLIFKAIDIDGNGEIDLAE 57 Query: 153 FCAVVGGL 160 F + Sbjct: 58 FTKFAAAV 65 Score = 37.2 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 28/61 (45%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 76 +DE L +K +D D G L+ EE + + V I D +G+G + +EF+ Sbjct: 71 SDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGYEKVVDQIMKADANGDGYITLEEFL 130 Query: 77 E 77 Sbjct: 131 A 131 Score = 26.8 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 18/42 (42%), Gaps = 9/42 (21%) Query: 14 HFDADEIKRLGKRF---------KKLDLDNSGSLSVEEFMSL 46 +E+ K+F K D + G +++EEF++ Sbjct: 91 KLTKEEVTTFFKKFGYEKVVDQIMKADANGDGYITLEEFLAF 132 >1JFJ-A nrPDB Length = 134 Score = 82.3 bits (202), Expect = 9e-17, Method: Composition-based stats. Identities = 38/138 (27%), Positives = 69/138 (50%), Gaps = 15/138 (10%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSL----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIE-- 77 FK++D++ G++S EE + ++ L+Q + D DGNGE+D EF + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTI 137 G Q D + L+ +++ D+D DG ++ E V + K ++++ ++ Sbjct: 63 GSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEE--------VTSFFKKHGIEKVAEQV- 113 Query: 138 INADKDGDGRISFEEFCA 155 + AD +GDG I+ EEF Sbjct: 114 MKADANGDGYITLEEFLE 131 Score = 55.3 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 3/111 (2%) Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113 + + + D +G+G V ++E ++ EQ L+ F+ D D +G I E Sbjct: 1 MAEALFKEIDVNGDGAVSYEE-VKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFA 59 Query: 114 QVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHK 164 + + G +L D ++ + D DGDG+++ EE + I K Sbjct: 60 KFYGSIQGQDLSDDKIG--LKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEK 108 Score = 35.3 bits (80), Expect = 0.012, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 27/55 (49%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 L +K +D+D G L+ EE S + V + D +G+G + +EF+E Sbjct: 77 LKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKADANGDGYITLEEFLE 131 >3IFK-A nrPDB Length = 90 Score = 82.3 bits (202), Expect = 1e-16, Method: Composition-based stats. Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 4/90 (4%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGN 67 ++I + F D D G+++ +E + + L QNP +Q +I+ D DGN Sbjct: 1 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 60 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFR 97 G +DF EF+ +++ D E+++R AFR Sbjct: 61 GTIDFPEFLTMMARKMKDTDSEEEIREAFR 90 Score = 61.1 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 5/69 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF ++D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQDMINEV----DADGNGTIDF 65 Query: 151 EEFCAVVGG 159 EF ++ Sbjct: 66 PEFLTMMAR 74 Score = 37.2 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 33/76 (43%), Gaps = 1/76 (1%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 + +FD DG+G + KE + + + E +L+ D D +G I E + Sbjct: 13 KEAFSLFDKDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTM 71 Query: 116 LKMMVGNNLKDTQLQQ 131 + + + + ++++ Sbjct: 72 MARKMKDTDSEEEIRE 87 >1GGW-A nrPDB Length = 140 Score = 81.5 bits (200), Expect = 2e-16, Method: Composition-based stats. Identities = 30/139 (21%), Positives = 65/139 (46%), Gaps = 12/139 (8%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPEL-QQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQ 81 + F D +G + L QNP + + ++ EVD ++F++ +++ Sbjct: 7 YKQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAEI-TEIESTLPAEVDMEQFLQVLNR 65 Query: 82 ---FSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII 138 F + GD E+ ++ F+++D D G I GEL VL + G L + ++ +++ + Sbjct: 66 PNGFDMPGDPEEFVK-GFQVFDKDATGMIGVGELRYVLTSL-GEKLSNEEMDELLKGVPV 123 Query: 139 NADKDGDGRISFEEFCAVV 157 DG +++ +F ++ Sbjct: 124 K-----DGMVNYHDFVQMI 137 Score = 33.4 bits (75), Expect = 0.057, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 29/65 (44%), Gaps = 5/65 (7%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFM----SLPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 + + K F+ D D +G + V E SL E N + ++ +G V++ + Sbjct: 74 DPEEFVKGFQVFDKDATGMIGVGELRYVLTSLGEKLSNEEMDELLKGVPV-KDGMVNYHD 132 Query: 75 FIEGV 79 F++ + Sbjct: 133 FVQMI 137 >5YPX-A nrPDB Length = 223 Score = 81.1 bits (199), Expect = 2e-16, Method: Composition-based stats. Identities = 41/158 (25%), Positives = 77/158 (48%), Gaps = 11/158 (6%) Query: 4 EASYPLEMCSHFDADEIKRL----GKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVI 59 E Y HF E++ L + L +D + L + + ++ L+ RV Sbjct: 30 EELYKTSCQKHFTKTEVESLIICYKNLLEGLKMDRN--LFRDILHQKFNMTEDLLMDRVF 87 Query: 60 DIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM 119 FD D + + E++EG+S F ++G ++K+ + F ++D++ DGYIS E+FQ+LK Sbjct: 88 RAFDKDSDSYISLTEWVEGLSVF-LRGTLDEKMEYTFTVFDLNGDGYISREEMFQMLKTC 146 Query: 120 VGNNLKDTQLQQ----IVDKTIINADKDGDGRISFEEF 153 + + + +V+ + D D D R+S ++F Sbjct: 147 LVKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKKDF 184 Score = 39.9 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 35/86 (40%), Gaps = 5/86 (5%) Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQI 132 + + ++ + FR +D D D YIS E + L + + L + Sbjct: 64 RNLFRDILHQKFNMTEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLDEK----- 118 Query: 133 VDKTIINADKDGDGRISFEEFCAVVG 158 ++ T D +GDG IS EE ++ Sbjct: 119 MEYTFTVFDLNGDGYISREEMFQMLK 144 Score = 27.2 bits (59), Expect = 3.3, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 24/57 (42%), Gaps = 4/57 (7%) Query: 113 FQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVD 169 + + ++ T+ ++D+ DKD D IS E+ GL + + +D Sbjct: 64 RNLFRDILHQKFNMTE-DLLMDRVFRAFDKDSDSYISLTEWV---EGLSVFLRGTLD 116 >3J04-B nrPDB Length = 143 Score = 79.2 bits (194), Expect = 8e-16, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 57/144 (39%), Gaps = 5/144 (3%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 FD +I+ + F +D + G + E+ + ++ ++ G ++F Sbjct: 1 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEGMMSEAPGPINFTM 60 Query: 75 FIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVD 134 F+ + D E +R AF +D + G+I L ++L M D + VD Sbjct: 61 FLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTM-----GDRFTDEEVD 115 Query: 135 KTIINADKDGDGRISFEEFCAVVG 158 + A D G ++ EF ++ Sbjct: 116 EMYREAPIDKKGNFNYVEFTRILK 139 >5MWC-D nrPDB Length = 311 Score = 78.8 bits (193), Expect = 1e-15, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 5/87 (5%) Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTI 137 + + E++L FR +D D DG+I E +++ + G L D D+ Sbjct: 139 MANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIR-LTGEQLTDEDP----DEIF 193 Query: 138 INADKDGDGRISFEEFCAVVGGLDIHK 164 ++D D +GRI F+EF +V + + Sbjct: 194 GDSDTDKNGRIDFDEFLKMVENVQLSM 220 Score = 57.3 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN----PLVQRVIDIFDTDGNGEVDFKEFI 76 + L + F+ D D G + EEF + L + DTD NG +DF EF+ Sbjct: 151 EELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFL 210 Query: 77 EGV 79 + V Sbjct: 211 KMV 213 Score = 42.6 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 36/83 (43%), Gaps = 3/83 (3%) Query: 35 SGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRF 94 G + ++ + + FD DG+G +D +EF G+ + + + ++ Sbjct: 135 DGPVMANSLTAM--VPSEEELSECFRTFDKDGDGFIDREEF-GGIIRLTGEQLTDEDPDE 191 Query: 95 AFRIYDMDKDGYISNGELFQVLK 117 F D DK+G I E ++++ Sbjct: 192 IFGDSDTDKNGRIDFDEFLKMVE 214 Score = 27.6 bits (60), Expect = 2.8, Method: Composition-based stats. Identities = 8/45 (17%), Positives = 18/45 (40%), Gaps = 2/45 (4%) Query: 14 HFDADEIKRLG--KRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ 56 +++ + F D D +G + +EF+ + E Q + Sbjct: 178 RLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFLKMVENVQLSMAD 222 >3AAJ-A nrPDB Length = 167 Score = 78.8 bits (193), Expect = 1e-15, Method: Composition-based stats. Identities = 47/156 (30%), Positives = 67/156 (42%), Gaps = 23/156 (14%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQQ----NP-LVQRVIDIFDTDGNGEVDFKEFIE 77 L F+++D D SG +S E NP V+ +I +FD + V+F EF Sbjct: 6 LWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEF-T 64 Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTI 137 GV ++ FR YD D G I EL Q + G L D Q D I Sbjct: 65 GVWKYITDWQN------VFRTYDRDNSGMIDKNELKQ---ALSGYRLSD----QFHDILI 111 Query: 138 INADKDGDGRISFEEFCA---VVGGL-DIHKKMVVD 169 D+ G G+I+F++F V+ L DI ++ D Sbjct: 112 RKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTD 147 Score = 55.7 bits (133), Expect = 9e-09, Method: Composition-based stats. Identities = 26/93 (27%), Positives = 36/93 (38%), Gaps = 9/93 (9%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPEL--QQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 I F+ D DNSG + E + +I FD G G++ F +FI+ Sbjct: 70 ITDWQNVFRTYDRDNSGMIDKNELKQALSGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQ 129 Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNG 110 G D FR YD D+DG+I Sbjct: 130 GCIVLQRLTDI-------FRRYDTDQDGWIQVS 155 >5COC-A nrPDB Length = 130 Score = 76.9 bits (188), Expect = 4e-15, Method: Composition-based stats. Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 15/125 (12%) Query: 40 VEEFMSLPEL---QQNPLVQRVIDIFDTDGN--GEVDFKEFIEGVSQFSVKGDKEQKLRF 94 E + LP L Q+N +Q + D N E + ++ + + + Sbjct: 13 FYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKCLNDAQAAAEECIA-----EFKE 67 Query: 95 AFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 AF ++D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F EF Sbjct: 68 AFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQDMINEV----DADGNGTIDFPEFL 122 Query: 155 AVVGG 159 ++ Sbjct: 123 TMMAR 127 Score = 69.6 bits (169), Expect = 7e-13, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 4/80 (5%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDT 64 L + I + F D D G+++ +E + + L QNP +Q +I+ D Sbjct: 51 LNDAQAAAEECIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDA 110 Query: 65 DGNGEVDFKEFIEGVSQFSV 84 DGNG +DF EF+ +++ Sbjct: 111 DGNGTIDFPEFLTMMARKMK 130 >2BL0-C nrPDB Length = 142 Score = 76.9 bits (188), Expect = 5e-15, Method: Composition-based stats. Identities = 31/145 (21%), Positives = 62/145 (42%), Gaps = 10/145 (6%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPEL----QQNPLVQRVIDIFDTDGNGEVDF 72 D++ + F+ D + +G ++ E ++ + + + + D GNG++ F Sbjct: 2 DDQVSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQF 61 Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQI 132 EF+ + + + E LR AFR +D + GYI L L + G+ LK + + Sbjct: 62 PEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNL-GDRLKPHEFAEF 120 Query: 133 VDKTIINADKDGDGRISFEEFCAVV 157 + T G+I ++ F + Sbjct: 121 LGITETE-----KGQIRYDNFINTM 140 Score = 49.9 bits (118), Expect = 5e-07, Method: Composition-based stats. Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 5/73 (6%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D+ + + AF ++D ++ G+I+ L VLK G ++ ++ AD G+G Sbjct: 3 DQVSEFKEAFELFDSERTGFITKEGLQTVLKQF-GVRVEPAAF----NEMFNEADATGNG 57 Query: 147 RISFEEFCAVVGG 159 +I F EF +++G Sbjct: 58 KIQFPEFLSMMGR 70 >3JAX-C nrPDB Length = 151 Score = 76.5 bits (187), Expect = 5e-15, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 65/151 (43%), Gaps = 14/151 (9%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIFDTDGNGEVD-- 71 F ++ + F+ D G + + + L QNP V+ + + E++ Sbjct: 4 FSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLK 63 Query: 72 ---FKEFIEGVSQFSVKGDKE--QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD 126 F++F+ + + D+ + R++D + +G + E+ VL + G + + Sbjct: 64 TLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTL-GEKMTE 122 Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 +++Q+V +D +G I++EE +V Sbjct: 123 EEVEQLVAGH-----EDSNGCINYEELVRMV 148 >2HF5-A nrPDB Length = 68 Score = 75.4 bits (184), Expect = 1e-14, Method: Composition-based stats. Identities = 26/65 (40%), Positives = 42/65 (64%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 +Q +I+ D DGNG +DF EF+ +++ D E+++R AFR++D D +GYIS EL Sbjct: 3 LQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRH 62 Query: 115 VLKMM 119 V+ + Sbjct: 63 VMTNL 67 Score = 40.3 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 +L+ D D +G I E ++ +KDT ++ + + DKDG+G IS Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISA 57 Query: 151 EEFCAVVGGL 160 E V+ L Sbjct: 58 AELRHVMTNL 67 Score = 34.5 bits (78), Expect = 0.024, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLP-----ELQQNPLVQRVIDIFDTDGNGEVDFKEF 75 L ++D D +G++ EF+++ + ++ +FD DGNG + E Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 Query: 76 IEGVS 80 ++ Sbjct: 61 RHVMT 65 Score = 29.5 bits (65), Expect = 0.65, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 15/32 (46%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLP 47 D D + + + F+ D D +G +S E + Sbjct: 33 DTDSEEEIREAFRVFDKDGNGYISAAELRHVM 64 >1FW4-A nrPDB Length = 71 Score = 75.4 bits (184), Expect = 1e-14, Method: Composition-based stats. Identities = 30/75 (40%), Positives = 46/75 (61%), Gaps = 5/75 (6%) Query: 85 KGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDG 144 D E+++R AFR++D D +GYIS EL V+ + G L D + VD+ I AD DG Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTDEE----VDEMIREADIDG 55 Query: 145 DGRISFEEFCAVVGG 159 DG++++EEF ++ Sbjct: 56 DGQVNYEEFVQMMTA 70 Score = 46.1 bits (108), Expect = 7e-06, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E + L V +I D DG+G+V+ Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 60 Query: 72 FKEFIEGVSQF 82 ++EF++ ++ Sbjct: 61 YEEFVQMMTAK 71 Score = 33.8 bits (76), Expect = 0.037, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Query: 50 QQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISN 109 ++ +FD DGNG + E ++ K ++++ R D+D DG ++ Sbjct: 3 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLT-DEEVDEMIREADIDGDGQVNY 61 Query: 110 GELFQVLKM 118 E Q++ Sbjct: 62 EEFVQMMTA 70 Score = 26.4 bits (57), Expect = 6.7, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 18/35 (51%) Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 DT ++ + + DKDG+G IS E V+ L Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL 35 >2KN2-A nrPDB Length = 92 Score = 75.4 bits (184), Expect = 1e-14, Method: Composition-based stats. Identities = 28/76 (36%), Positives = 48/76 (63%), Gaps = 5/76 (6%) Query: 82 FSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINAD 141 + D E++L+ AF+++D D++GYIS EL V+ + G L D +++Q I AD Sbjct: 1 GHMDTDAEEELKEAFKVFDKDQNGYISASELRHVMINL-GEKLTDEEVEQ----MIKEAD 55 Query: 142 KDGDGRISFEEFCAVV 157 DGDG++++EEF ++ Sbjct: 56 LDGDGQVNYEEFVKMM 71 Score = 46.1 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 4/70 (5%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS----LPELQQNPLVQRVIDIFDTDGNGE 69 H D D + L + FK D D +G +S E L E + V+++I D DG+G+ Sbjct: 2 HMDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQ 61 Query: 70 VDFKEFIEGV 79 V+++EF++ + Sbjct: 62 VNYEEFVKMM 71 Score = 34.2 bits (77), Expect = 0.032, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 30/74 (40%), Gaps = 1/74 (1%) Query: 47 PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGY 106 + ++ +FD D NG + E + K ++++ + D+D DG Sbjct: 3 MDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLT-DEEVEQMIKEADLDGDGQ 61 Query: 107 ISNGELFQVLKMMV 120 ++ E +++ + Sbjct: 62 VNYEEFVKMMMTVR 75 >1W7I-B nrPDB Length = 151 Score = 73.8 bits (180), Expect = 3e-14, Method: Composition-based stats. Identities = 33/151 (21%), Positives = 68/151 (45%), Gaps = 16/151 (10%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIF-----DTDGN 67 F+ D+++ + F+ D G + + + L QNP V+ + D + Sbjct: 3 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 62 Query: 68 GEVDFKEFI---EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNL 124 VDF+ F+ + V++ +G E L FR++D + +G + EL VL + G + Sbjct: 63 RRVDFETFLPMLQAVAKNRGQGTYEDYLE-GFRVFDKEGNGKVMGAELRHVLTTL-GEKM 120 Query: 125 KDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 + +++ ++ +D +G I++E F Sbjct: 121 TEEEVETVLAGH-----EDSNGCINYEAFLK 146 Score = 43.0 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 39/79 (49%), Gaps = 3/79 (3%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D+ ++ + AF ++D DG I + V++ + G N + ++ +++ +D+ Sbjct: 7 DQLEEFKEAFELFDRVGDGKILYSQCGDVMRAL-GQNPTNAEVLKVLGN--PKSDELKSR 63 Query: 147 RISFEEFCAVVGGLDIHKK 165 R+ FE F ++ + ++ Sbjct: 64 RVDFETFLPMLQAVAKNRG 82 >2KZ2-A nrPDB Length = 94 Score = 73.8 bits (180), Expect = 3e-14, Method: Composition-based stats. Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 5/78 (6%) Query: 82 FSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINAD 141 D E+++R AFR+ D D +GYIS EL V+ + G L D + VD+ I AD Sbjct: 21 LMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNL-GEKLTDEE----VDEMIREAD 75 Query: 142 KDGDGRISFEEFCAVVGG 159 DGDG++++EEF ++ Sbjct: 76 IDGDGQVNYEEFVQMMTA 93 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 D D + + + F+ D D +G +S E + L V +I D DG+G+V+ Sbjct: 24 DTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 83 Query: 72 FKEFIEGVSQF 82 ++EF++ ++ Sbjct: 84 YEEFVQMMTAK 94 Score = 33.0 bits (74), Expect = 0.071, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 31/73 (42%), Gaps = 1/73 (1%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDG 105 + + ++ + D DGNG + E ++ K ++++ R D+D DG Sbjct: 22 MKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLT-DEEVDEMIREADIDGDG 80 Query: 106 YISNGELFQVLKM 118 ++ E Q++ Sbjct: 81 QVNYEEFVQMMTA 93 Score = 27.2 bits (59), Expect = 4.1, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 20/37 (54%) Query: 124 LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 +KDT ++ + + DKDG+G IS E V+ L Sbjct: 22 MKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNL 58 >1M39-A nrPDB Length = 89 Score = 73.4 bits (179), Expect = 4e-14, Method: Composition-based stats. Identities = 30/94 (31%), Positives = 59/94 (62%), Gaps = 5/94 (5%) Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 ++F +F+ ++Q + D ++++ AF+++D D+ G IS L +V K + G NL D +L Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-GENLTDEEL 59 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 Q+++D+ AD+DGDG +S +EF ++ ++ Sbjct: 60 QEMIDE----ADRDGDGEVSEQEFLRIMKKTSLY 89 Score = 36.5 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFM----SLPELQQNPLVQRVIDIFDTDGNGEVDF 72 D + + K FK D D +G +S + L E + +Q +ID D DG+GEV Sbjct: 17 KDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSE 76 Query: 73 KEFIEGVSQFSV 84 +EF+ + + S+ Sbjct: 77 QEFLRIMKKTSL 88 Score = 32.6 bits (73), Expect = 0.083, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Query: 44 MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDK 103 + E + + +FD D G++ FK ++ V++ + +++L+ D D Sbjct: 12 QKMSEKDTKEEILKAFKLFDDDETGKISFKN-LKRVAKELGENLTDEELQEMIDEADRDG 70 Query: 104 DGYISNGELFQVLKM 118 DG +S E +++K Sbjct: 71 DGEVSEQEFLRIMKK 85 >5H7D-E nrPDB Length = 120 Score = 71.9 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 19/121 (15%) Query: 42 EFMSLPEL---QQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRI 98 E +LP L Q + ++D N + + K ++ Q + AF + Sbjct: 16 EIFTLPNLNGRQVAAFISSLLDDPSQSAN-----------LLAEAKKLNQIQAFKEAFSL 64 Query: 99 YDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 +D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F EF ++ Sbjct: 65 FDKDGDGTITTKELGTVMRSL-GQNPTEAELQDMINEV----DADGNGTIDFPEFLTMMA 119 Query: 159 G 159 Sbjct: 120 R 120 Score = 70.7 bits (172), Expect = 3e-13, Method: Composition-based stats. Identities = 21/68 (30%), Positives = 39/68 (57%), Gaps = 4/68 (5%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 ++I+ + F D D G+++ +E + + L QNP +Q +I+ D DGNG +DF Sbjct: 53 NQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 112 Query: 74 EFIEGVSQ 81 EF+ +++ Sbjct: 113 EFLTMMAR 120 >3DTP-E nrPDB Length = 196 Score = 71.5 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 60/151 (39%), Gaps = 6/151 (3%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 F +++ + F+ +D D G +S + + + ++ +D + G ++F Sbjct: 51 FTQHQVQEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMVAEAPGPINFTM 110 Query: 75 FIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVD 134 F+ D+E + AF ++D + DG L + L G + VD Sbjct: 111 FLTIFGDRIAGTDEEDVIVNAFNLFD-EGDGKCKEETLKRSLTT-WGEKFSQDE----VD 164 Query: 135 KTIINADKDGDGRISFEEFCAVVGGLDIHKK 165 + + A DG+G I ++F ++ + Sbjct: 165 QALSEAPIDGNGLIDIKKFAQILTKGAKEEG 195 >3MSE-B nrPDB Length = 180 Score = 71.5 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 36/146 (24%), Positives = 71/146 (48%), Gaps = 11/146 (7%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMSLPE--LQQNPLVQRVIDIFDTDGNGEVDFKEF 75 + IK + + F KLD +++GSLS E ++ + + R++ D + G + + EF Sbjct: 36 NHIKYINELFYKLDTNHNGSLSHREIYTVLASVGIKKWDINRILQALDINDRGNITYTEF 95 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL--KMMVGNNLKDT--QLQQ 131 + G ++ K + L+ AF D D+DGYIS ++ ++ K++ N++ + + Sbjct: 96 MAGCYRW--KNIESTFLKAAFNKIDKDEDGYISKSDIVSLVHDKVLDNNDIDNFFLSVHS 153 Query: 132 IVDKTIINADKDGDGRISFEEFCAVV 157 I + +ISF+EF + Sbjct: 154 IKKGIPREHIIN---KISFQEFKDYM 176 >2LV7-A nrPDB Length = 100 Score = 71.1 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 24/73 (32%), Positives = 45/73 (61%), Gaps = 5/73 (6%) Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 D+ +++R AF+++D D +G+IS EL ++ + G + +L+ I+ + D DGD Sbjct: 32 EDELEEIREAFKVFDRDGNGFISKQELGTAMRSL-GYMPNEVELEVIIQRL----DMDGD 86 Query: 146 GRISFEEFCAVVG 158 G++ FEEF ++G Sbjct: 87 GQVDFEEFVTLLG 99 Score = 57.6 bits (138), Expect = 2e-09, Method: Composition-based stats. Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 4/70 (5%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEV 70 DE++ + + FK D D +G +S +E + + L P ++ +I D DG+G+V Sbjct: 30 IPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQV 89 Query: 71 DFKEFIEGVS 80 DF+EF+ + Sbjct: 90 DFEEFVTLLG 99 >2RO9-A nrPDB Length = 69 Score = 70.7 bits (172), Expect = 3e-13, Method: Composition-based stats. Identities = 31/71 (43%), Positives = 47/71 (66%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D E++L+ AFR++D D++G+IS EL V+ + G L D + VD+ I AD DGDG Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNL-GEKLTDEE----VDEMIREADVDGDG 55 Query: 147 RISFEEFCAVV 157 +I++EEF V+ Sbjct: 56 QINYEEFVKVM 66 Score = 43.0 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 32/66 (48%), Gaps = 4/66 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDFKEFI 76 + L + F+ D D +G +S E + L V +I D DG+G+++++EF+ Sbjct: 4 EELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFV 63 Query: 77 EGVSQF 82 + + Sbjct: 64 KVMMAK 69 Score = 33.0 bits (74), Expect = 0.062, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 29/69 (42%), Gaps = 1/69 (1%) Query: 50 QQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISN 109 ++ +FD D NG + E ++ K ++++ R D+D DG I+ Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLT-DEEVDEMIREADVDGDGQINY 59 Query: 110 GELFQVLKM 118 E +V+ Sbjct: 60 EEFVKVMMA 68 >2M5E-A nrPDB Length = 73 Score = 70.7 bits (172), Expect = 3e-13, Method: Composition-based stats. Identities = 29/75 (38%), Positives = 44/75 (58%), Gaps = 5/75 (6%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 + D E++L AF+++D D +G IS EL V+ + G L D + VD+ I AD Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNL-GEKLTDDE----VDEMIREADI 55 Query: 143 DGDGRISFEEFCAVV 157 DGDG I++EEF ++ Sbjct: 56 DGDGHINYEEFVRMM 70 Score = 43.4 bits (101), Expect = 4e-05, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 4/66 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDFKEFI 76 + L + FK D D +G +S E + L V +I D DG+G ++++EF+ Sbjct: 8 EELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFV 67 Query: 77 EGVSQF 82 + Sbjct: 68 RMMVSK 73 Score = 33.0 bits (74), Expect = 0.065, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 31/71 (43%), Gaps = 1/71 (1%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDG 105 + E + +FD DGNG + E ++ K + ++ R D+D DG Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLT-DDEVDEMIREADIDGDG 59 Query: 106 YISNGELFQVL 116 +I+ E +++ Sbjct: 60 HINYEEFVRMM 70 >2ROB-A nrPDB Length = 70 Score = 70.0 bits (170), Expect = 5e-13, Method: Composition-based stats. Identities = 28/71 (39%), Positives = 47/71 (66%), Gaps = 5/71 (7%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D E++L+ AF+++D D++GYIS EL V+ + G L D +++Q I AD DGDG Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINL-GEKLTDEEVEQ----MIKEADLDGDG 55 Query: 147 RISFEEFCAVV 157 ++++EEF ++ Sbjct: 56 QVNYEEFVKMM 66 Score = 42.6 bits (99), Expect = 8e-05, Method: Composition-based stats. Identities = 19/63 (30%), Positives = 35/63 (55%), Gaps = 4/63 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMS----LPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 76 + L + FK D D +G +S E L E + V+++I D DG+G+V+++EF+ Sbjct: 4 EELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFV 63 Query: 77 EGV 79 + + Sbjct: 64 KMM 66 Score = 32.2 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 29/71 (40%), Gaps = 1/71 (1%) Query: 50 QQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISN 109 ++ +FD D NG + E + K ++++ + D+D DG ++ Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLT-DEEVEQMIKEADLDGDGQVNY 59 Query: 110 GELFQVLKMMV 120 E +++ + Sbjct: 60 EEFVKMMMTVR 70 >3I5H-B nrPDB Length = 153 Score = 70.0 bits (170), Expect = 5e-13, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 51/122 (41%), Gaps = 1/122 (0%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFK 73 +++ L + F +D D G + +E+ + ++ + G+++F Sbjct: 9 KLSQRQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAMLKECPGQLNFT 68 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 F+ + D E LR AF ++D D G+I L +L+ M G+N +++ + Sbjct: 69 AFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENM-GDNFSKEEIKNVW 127 Query: 134 DK 135 Sbjct: 128 KD 129 Score = 27.2 bits (59), Expect = 3.3, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 20/67 (29%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQF 82 L F D D G + + L E + + I D + + + V Sbjct: 87 LRNAFSMFDEDGQGFIPEDYLKDLLENMGDNFSKEEIKNVWKDAPLKNKQFNYNKMVDIK 146 Query: 83 SVKGDKE 89 D++ Sbjct: 147 GKAEDED 153 >3E3R-A nrPDB Length = 204 Score = 69.2 bits (168), Expect = 7e-13, Method: Composition-based stats. Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 8/149 (5%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPE----LQQNPLVQRVIDIFDTDGNGEVDFKEF 75 I+ L + F++LD D S SL +EF + + V +D +G+G +D +EF Sbjct: 36 IQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEF 95 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL--QQIV 133 + + + +E + AF D DG ++ +L V ++ + +++ Sbjct: 96 LRALRPPMSQA-REAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVL 154 Query: 134 DKTIINAD-KDGDGRISFEEFCAVVGGLD 161 + + N D + DG+++ EF G+ Sbjct: 155 RRFLDNFDSSEKDGQVTLAEFQDYYSGVS 183 Score = 32.6 bits (73), Expect = 0.082, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 39/98 (39%), Gaps = 12/98 (12%) Query: 7 YPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL-----------V 55 + + + F KLD G ++V++ + + +P + Sbjct: 95 FLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVL 154 Query: 56 QRVIDIFD-TDGNGEVDFKEFIEGVSQFSVKGDKEQKL 92 +R +D FD ++ +G+V EF + S S + +++ Sbjct: 155 RRFLDNFDSSEKDGQVTLAEFQDYYSGVSASMNTDEEF 192 >2RO8-A nrPDB Length = 79 Score = 68.8 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGN 67 ++I + F D D G ++ +E + + L QNP +Q +I+ D DGN Sbjct: 1 ADQLTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 60 Query: 68 GEVDFKEFIEGVSQFSVKG 86 G +DF EF+ +++ Sbjct: 61 GTIDFPEFLNLMARKMKDT 79 Score = 61.5 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 5/69 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF ++D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSL-GQNPTEAELQDMINEV----DADGNGTIDF 65 Query: 151 EEFCAVVGG 159 EF ++ Sbjct: 66 PEFLNLMAR 74 Score = 32.6 bits (73), Expect = 0.078, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 + +FD DG+G + KE + + + E +L+ D D +G I E + Sbjct: 13 KEAFSLFDKDGDGCITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNL 71 Query: 116 L 116 + Sbjct: 72 M 72 >2I08-A nrPDB Length = 78 Score = 68.8 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNG 68 ++I + F D D G+++ +E + + L NP +Q +I+ D DGNG Sbjct: 2 DQLTEEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNG 61 Query: 69 EVDFKEFIEGVSQFSV 84 +DF EF+ +++ Sbjct: 62 TIDFPEFLTMMARIMK 77 Score = 65.0 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 5/73 (6%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF +YD D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F Sbjct: 11 EFKEAFSLYDKDGDGTITTKELGTVMRSL-GLNPTEAELQDMINEV----DADGNGTIDF 65 Query: 151 EEFCAVVGGLDIH 163 EF ++ + + Sbjct: 66 PEFLTMMARIMKY 78 Score = 33.8 bits (76), Expect = 0.040, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 27/65 (41%), Gaps = 1/65 (1%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 + ++D DG+G + KE + + E +L+ D D +G I E + Sbjct: 13 KEAFSLYDKDGDGTITTKELGTVM-RSLGLNPTEAELQDMINEVDADGNGTIDFPEFLTM 71 Query: 116 LKMMV 120 + ++ Sbjct: 72 MARIM 76 >2K7C-A nrPDB Length = 72 Score = 68.4 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 24/70 (34%), Positives = 43/70 (61%), Gaps = 4/70 (5%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 ++LR AFR +D + DG IS EL + ++ ++G+ + +++I I + D +GDGR+ Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEI----IRDVDLNGDGRVD 62 Query: 150 FEEFCAVVGG 159 FEEF ++ Sbjct: 63 FEEFVRMMSR 72 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 5/67 (7%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMS-----LPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 +K L F++ D + G +S E L + ++ +I D +G+G VDF+E Sbjct: 6 VKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEE 65 Query: 75 FIEGVSQ 81 F+ +S+ Sbjct: 66 FVRMMSR 72 Score = 35.7 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 28/62 (45%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 ++ FDT+G+GE+ E E + + + + R D++ DG + E + Sbjct: 9 LRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVR 68 Query: 115 VL 116 ++ Sbjct: 69 MM 70 >3SIA-A nrPDB Length = 220 Score = 68.4 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 19/124 (15%) Query: 3 NEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEF--MSLPEL--QQNPLVQRV 58 N +PL + D+ R+ + F +D D SG+L + E P R+ Sbjct: 35 NTWWFPL--LNTIPLDQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRLSPQTALRM 92 Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMD---KDGYISNGELFQV 115 + IFDTD NG + F EF+ + +F A+ ++ M+ + G + E+ Sbjct: 93 MRIFDTDFNGHISFYEFM-AMYKFM---------ELAYNLFVMNARARSGTLEPHEILPA 142 Query: 116 LKMM 119 L+ + Sbjct: 143 LQQL 146 Score = 36.8 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 7/68 (10%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ-QIVDKTIINADKDGDGRISFEEFC 154 F D D+ G + EL M+G +L Q + + D D +G ISF EF Sbjct: 57 FMGVDRDRSGTLEINEL------MMGQFPGGIRLSPQTALRMMRIFDTDFNGHISFYEFM 110 Query: 155 AVVGGLDI 162 A+ +++ Sbjct: 111 AMYKFMEL 118 >5TBY-E nrPDB Length = 166 Score = 67.7 bits (164), Expect = 2e-12, Method: Composition-based stats. Identities = 23/147 (15%), Positives = 58/147 (39%), Gaps = 6/147 (4%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPLVQRVIDIFDTDGNGEVD 71 S F+ +I+ + F +D + G + + + L + + ID + G ++ Sbjct: 19 SMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEAPGPIN 78 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 F F+ + D E+ + AF+++D + G + + ++L + ++ Sbjct: 79 FTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQA-----ERFSKE 133 Query: 132 IVDKTIINADKDGDGRISFEEFCAVVG 158 VD+ D G + ++ ++ Sbjct: 134 EVDQMFAAFPPDVTGNLDYKNLVHIIT 160 Score = 29.1 bits (64), Expect = 0.86, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 23/65 (35%), Gaps = 4/65 (6%) Query: 25 KRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDFKEFIEGVS 80 FK D + G L + + Q V ++ F D G +D+K + ++ Sbjct: 101 NAFKVFDPEGKGVLKADYVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIIT 160 Query: 81 QFSVK 85 K Sbjct: 161 HGEEK 165 >6FSA-D nrPDB Length = 199 Score = 67.7 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 31/163 (19%), Positives = 67/163 (41%), Gaps = 17/163 (10%) Query: 8 PLEMCSHFDADEIKRLGKRFKKLDLDNSG--SLSVEEFMS-LPELQQNPLVQRVIDIF-- 62 P ++ F ++I+ + F D ++ + L L QNP V+ + Sbjct: 43 PSKIKIEFTPEQIEEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 102 Query: 63 ---DTDGNGEVDFKEFIEGVSQFSVKGD--KEQKLRFAFRIYDMDKDGYISNGELFQVLK 117 + + +DF F+ + S D + R++D + +G + EL VL Sbjct: 103 PKQEELNSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 162 Query: 118 MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA-VVGG 159 + G L + ++++++ +D +G I++E F ++ G Sbjct: 163 TL-GEKLTEDEVEKLM-----AGQEDSNGCINYEAFVKHIMAG 199 >2E6W-A nrPDB Length = 100 Score = 67.3 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 7/81 (8%) Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNN-------LKDTQLQQIVDKTII 138 G +KL++AF +YD++KDGYI+ E+ ++K + L++ + V++ Sbjct: 5 GTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFE 64 Query: 139 NADKDGDGRISFEEFCAVVGG 159 D++ DG ++ EEF Sbjct: 65 KMDRNQDGVVTIEEFLEACQK 85 Score = 35.3 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 30/75 (40%), Gaps = 16/75 (21%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMS----------------LPELQQNPLVQRVIDIFDT 64 ++L F D++ G ++ EE ++ L E V+R + D Sbjct: 9 EKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDR 68 Query: 65 DGNGEVDFKEFIEGV 79 + +G V +EF+E Sbjct: 69 NQDGVVTIEEFLEAC 83 >1B7T-Y nrPDB Length = 156 Score = 66.9 bits (162), Expect = 4e-12, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 63/148 (42%), Gaps = 6/148 (4%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD 71 + +I+ + + F +D+D G +S E+ ++ E + + + G ++ Sbjct: 9 LTKLPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAMLKEAPGPLN 68 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 F F+ S D E+ +R AF ++D + ++ + +L N+ D + Sbjct: 69 FTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLL-----ENMGDNFNKD 123 Query: 132 IVDKTIINADKDGDGRISFEEFCAVVGG 159 + T A +G G+ + +F A++ G Sbjct: 124 EMRMTFKEAPVEG-GKFDYVKFTAMIKG 150 >5JOJ-A nrPDB Length = 97 Score = 66.5 bits (161), Expect = 6e-12, Method: Composition-based stats. Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Query: 79 VSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII 138 +++ SV ++ +LR AF D D +GYIS EL + K L ++++I + + Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAAC-LPLPGYRVREITENLMA 59 Query: 139 NADKDGDGRISFEEFCAVVGGL 160 D D DGRISF+EF + GL Sbjct: 60 TGDLDQDGRISFDEFIKIFHGL 81 Score = 46.1 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 8/71 (11%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLV--------QRVIDIFDTDGN 67 +E+ L + F K+D D +G +S E L + PL + ++ D D + Sbjct: 7 SDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQD 66 Query: 68 GEVDFKEFIEG 78 G + F EFI+ Sbjct: 67 GRISFDEFIKI 77 Score = 27.6 bits (60), Expect = 2.4, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 ++ D ++ ++ + D DG+G ISF E + + Sbjct: 5 SVSDEEMMEL-REAFAKVDTDGNGYISFNELNDLFKAACL 43 >5JOL-A nrPDB Length = 82 Score = 65.7 bits (159), Expect = 9e-12, Method: Composition-based stats. Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Query: 79 VSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII 138 +++ SV ++ +LR AF D D +GYIS EL + K L ++++I + + Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAAC-LPLPGYRVREITENLMA 59 Query: 139 NADKDGDGRISFEEFCAVVGGL 160 D D DGRISF+EF + GL Sbjct: 60 TGDLDQDGRISFDEFIKIFHGL 81 Score = 45.3 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 8/71 (11%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLV--------QRVIDIFDTDGN 67 +E+ L + F K+D D +G +S E L + PL + ++ D D + Sbjct: 7 SDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQD 66 Query: 68 GEVDFKEFIEG 78 G + F EFI+ Sbjct: 67 GRISFDEFIKI 77 Score = 27.6 bits (60), Expect = 3.0, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 ++ D ++ ++ + D DG+G ISF E + + Sbjct: 5 SVSDEEMMEL-REAFAKVDTDGNGYISFNELNDLFKAACL 43 >5H53-C nrPDB Length = 153 Score = 65.7 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 63/156 (40%), Gaps = 14/156 (8%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIFDTDGNGE--- 69 F ++ + F D +++ + L L NP V + N E Sbjct: 4 EFSKEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNA 63 Query: 70 --VDFKEFIEGVSQFSVKGD--KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 ++F++F+ + S D + R++D + +G + EL VL + G +K Sbjct: 64 KKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL-GEKMK 122 Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 + +++ ++ +D +G I++E F + +D Sbjct: 123 EEEVE-----ALMAGQEDSNGCINYEAFVKHIMSID 153 Score = 27.6 bits (60), Expect = 2.8, Method: Composition-based stats. Identities = 8/75 (10%), Positives = 29/75 (38%), Gaps = 3/75 (4%) Query: 6 SYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF--- 62 + ++ D + + + D + +G++ E + + + ++ Sbjct: 73 PMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAG 132 Query: 63 DTDGNGEVDFKEFIE 77 D NG ++++ F++ Sbjct: 133 QEDSNGCINYEAFVK 147 >5TBY-C nrPDB Length = 195 Score = 65.7 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 29/152 (19%), Positives = 61/152 (40%), Gaps = 16/152 (10%) Query: 14 HFDADEIKRLGKRFKKLDLDNSG--SLSVEEFMS-LPELQQNPLVQRVIDIF-----DTD 65 F ++I+ + F D ++ + L L QNP V+ + + Sbjct: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 Query: 66 GNGEVDFKEFIEGVSQFSVKGD--KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNN 123 +DF+ F+ + S D + R++D + +G + EL VL + G Sbjct: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL-GER 163 Query: 124 LKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 L + ++++++ +D +G I++E F Sbjct: 164 LTEDEVEKLM-----AGQEDSNGCINYEAFVK 190 Score = 27.6 bits (60), Expect = 2.5, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 30/76 (39%), Gaps = 7/76 (9%) Query: 9 LEMCSHFDADEIKRLGKRF----KKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIF- 62 L M H ++ + F + D + +G++ E L L + V + Sbjct: 115 LPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMA 174 Query: 63 -DTDGNGEVDFKEFIE 77 D NG ++++ F++ Sbjct: 175 GQEDSNGCINYEAFVK 190 >2AMI-A nrPDB Length = 96 Score = 65.4 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 5/80 (6%) Query: 80 SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIIN 139 + + +++Q++R AF ++D D G I EL ++ + K+ + K I Sbjct: 20 GRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEE-----IKKMISE 74 Query: 140 ADKDGDGRISFEEFCAVVGG 159 DKDG G I FEEF ++ Sbjct: 75 IDKDGSGTIDFEEFLTMMTA 94 Score = 62.7 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 37/73 (50%), Gaps = 4/73 (5%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL---VQRVIDIFDTDGNGEV 70 ++ + + + F D D SG++ +E ++ L P ++++I D DG+G + Sbjct: 24 LTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTI 83 Query: 71 DFKEFIEGVSQFS 83 DF+EF+ ++ Sbjct: 84 DFEEFLTMMTAKM 96 Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 30/64 (46%), Gaps = 1/64 (1%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 ++ D+FDTDG+G +D KE + + K+++++ D D G I E Sbjct: 32 IREAFDLFDTDGSGTIDAKELKVAMRALGFE-PKKEEIKKMISEIDKDGSGTIDFEEFLT 90 Query: 115 VLKM 118 ++ Sbjct: 91 MMTA 94 >4Q57-A nrPDB Length = 65 Score = 64.6 bits (156), Expect = 2e-11, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 5/68 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF ++D D DG I+ EL V++ + G N + +LQ ++++ D DG+G I F Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQDMINEV----DADGNGTIDF 57 Query: 151 EEFCAVVG 158 EF ++ Sbjct: 58 PEFLTMMA 65 Score = 62.7 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 4/65 (6%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFKEF 75 I + F D D G+++ +E + + L QNP +Q +I+ D DGNG +DF EF Sbjct: 1 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 60 Query: 76 IEGVS 80 + ++ Sbjct: 61 LTMMA 65 Score = 34.9 bits (79), Expect = 0.017, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 + +FD DG+G + KE + + + E +L+ D D +G I E + Sbjct: 5 KEAFSLFDKDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTM 63 Query: 116 L 116 + Sbjct: 64 M 64 >2K2I-A nrPDB Length = 79 Score = 64.2 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 28/84 (33%), Positives = 52/84 (61%), Gaps = 5/84 (5%) Query: 80 SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIIN 139 +Q + D ++++ AF+++D D+ G IS L +V K + G NL D +LQ+++D+ Sbjct: 1 TQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-GENLTDEELQEMIDE---- 55 Query: 140 ADKDGDGRISFEEFCAVVGGLDIH 163 AD+DGDG +S +EF ++ ++ Sbjct: 56 ADRDGDGEVSEQEFLRIMKKTSLY 79 Score = 35.7 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFM----SLPELQQNPLVQRVIDIFDTDGNGEVDF 72 D + + K FK D D +G +S + L E + +Q +ID D DG+GEV Sbjct: 7 KDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSE 66 Query: 73 KEFIEGVSQFSV 84 +EF+ + + S+ Sbjct: 67 QEFLRIMKKTSL 78 Score = 32.2 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Query: 44 MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDK 103 + E + + +FD D G++ FK ++ V++ + +++L+ D D Sbjct: 2 QKMSEKDTKEEILKAFKLFDDDETGKISFKN-LKRVAKELGENLTDEELQEMIDEADRDG 60 Query: 104 DGYISNGELFQVLKM 118 DG +S E +++K Sbjct: 61 DGEVSEQEFLRIMKK 75 >2B1U-A nrPDB Length = 71 Score = 63.8 bits (154), Expect = 3e-11, Method: Composition-based stats. Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 5/69 (7%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 + L+ AFR +D D DG+I+ EL + + L Q+ +D I AD D DGR++ Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAG-----LGQPLPQEELDAMIREADVDQDGRVN 60 Query: 150 FEEFCAVVG 158 +EEF ++ Sbjct: 61 YEEFARMLA 69 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQR----VIDIFDTDGNGEVDFKEF 75 ++ L F+ D D G ++V+E PL Q +I D D +G V+++EF Sbjct: 5 LEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEF 64 Query: 76 IEGVSQ 81 ++Q Sbjct: 65 ARMLAQ 70 Score = 34.5 bits (78), Expect = 0.023, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 53 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 +Q FD DG+G + E ++ + +++L R D+D+DG ++ E Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMA-GLGQPLPQEELDAMIREADVDQDGRVNYEEF 64 Query: 113 FQVLKM 118 ++L Sbjct: 65 ARMLAQ 70 Score = 28.0 bits (61), Expect = 2.0, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 15/30 (50%) Query: 131 QIVDKTIINADKDGDGRISFEEFCAVVGGL 160 + + D+DGDG I+ +E + GL Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGL 35 >1DFK-Y nrPDB Length = 139 Score = 63.8 bits (154), Expect = 3e-11, Method: Composition-based stats. Identities = 28/145 (19%), Positives = 62/145 (42%), Gaps = 6/145 (4%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 +I+ + + F +D+D G +S E+ ++ E + + + G ++F Sbjct: 1 LPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAMLKEAPGPLNFTM 60 Query: 75 FIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVD 134 F+ S D E+ +R AF ++D + ++ + +L N+ D + + Sbjct: 61 FLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLL-----ENMGDNFNKDEMR 115 Query: 135 KTIINADKDGDGRISFEEFCAVVGG 159 T A +G G+ + +F A++ G Sbjct: 116 MTFKEAPVEG-GKFDYVKFTAMIKG 139 >2OS8-B nrPDB Length = 157 Score = 63.8 bits (154), Expect = 3e-11, Method: Composition-based stats. Identities = 24/148 (16%), Positives = 57/148 (38%), Gaps = 6/148 (4%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD 71 + +I+ + + F +D + G + + + + + + + G ++ Sbjct: 10 LTKLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEAPGPLN 69 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 F F+ S D E+ +R AF ++D ++ + +L N+ D + Sbjct: 70 FTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLL-----ENMGDNFNKD 124 Query: 132 IVDKTIINADKDGDGRISFEEFCAVVGG 159 + T A +G G+ + F A++ G Sbjct: 125 EMRMTFKEAPVEG-GKFDYVRFVAMIKG 151 >1Y1X-A nrPDB Length = 191 Score = 63.0 bits (152), Expect = 5e-11, Method: Composition-based stats. Identities = 31/140 (22%), Positives = 64/140 (45%), Gaps = 16/140 (11%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLV----QRVIDIFDTDGNGEVDFKEFI 76 + L + F+ +D D SG++SV E + P ++++ ++D + +GE+ F EF Sbjct: 27 QELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDKNHSGEITFDEF- 85 Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKT 136 + + F + +R FR D DG + + E+ L G + + Q ++ K Sbjct: 86 KDLHHFILS------MREGFRKRDSSGDGRLDSNEVRAALLS-SGYQVSEQTFQALMRKF 138 Query: 137 IINADKDGDGRISFEEFCAV 156 D+ G + F+++ + Sbjct: 139 ----DRQRRGSLGFDDYVEL 154 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 5/68 (7%) Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 + Q+L FR D D G IS EL L G +++ + DK+ Sbjct: 23 MNDNQELMEWFRAVDTDGSGAISVPELNAALSSA-GVPFSLATTEKL----LHMYDKNHS 77 Query: 146 GRISFEEF 153 G I+F+EF Sbjct: 78 GEITFDEF 85 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 35/94 (37%), Gaps = 11/94 (11%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEE----FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEF 75 I + + F+K D G L E +S Q ++ FD G + F ++ Sbjct: 92 ILSMREGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQALMRKFDRQRRGSLGFDDY 151 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISN 109 +E ++R F YD ++ G ++ Sbjct: 152 VELSIFVC-------RVRNVFAFYDRERTGQVTF 178 >1I84-U nrPDB Length = 166 Score = 62.7 bits (151), Expect = 7e-11, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 58/154 (37%), Gaps = 6/154 (3%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPLVQRVIDIFDTDGNGEVD 71 S FD EI+ + F +D + G + ++ + + + + +D + +G ++ Sbjct: 17 SMFDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEASGPIN 76 Query: 72 FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 F F+ + D E + AF++ D D G I L ++L G + Sbjct: 77 FTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPEE---- 132 Query: 132 IVDKTIINADKDGDGRISFEEFCAVVGGLDIHKK 165 + D G + ++ C V+ + + Sbjct: 133 -IKNMWAAFPPDVAGNVDYKNICYVITHGEDAEG 165 >1JC2-A nrPDB Length = 76 Score = 61.5 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 46/78 (58%), Gaps = 5/78 (6%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 KG E++L FRI+D + DG+I EL ++L+ + +++ ++ + ++DK Sbjct: 3 DAKGKSEEELANCFRIFDKNADGFIDIEELGEILRAT-----GEHVIEEDIEDLMKDSDK 57 Query: 143 DGDGRISFEEFCAVVGGL 160 + DGRI F+EF ++ G+ Sbjct: 58 NNDGRIDFDEFLKMMEGV 75 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQ----NPLVQRVIDIFDTDGNGEVDFKEFI 76 + L F+ D + G + +EE + ++ ++ D + +G +DF EF+ Sbjct: 10 EELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFDEFL 69 Query: 77 EGV 79 + + Sbjct: 70 KMM 72 >1F55-A nrPDB Length = 77 Score = 61.1 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 4/77 (5%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGN 67 S+ ++I + F D DN+GS+S E + + L +P V +++ D DGN Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 60 Query: 68 GEVDFKEFIEGVSQFSV 84 +++F EF+ +S+ Sbjct: 61 HQIEFSEFLALMSRQLK 77 Score = 53.8 bits (128), Expect = 3e-08, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 5/69 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF ++D D +G IS+ EL V++ + G + + + V+ + D DG+ +I F Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSL-GLSPSEAE----VNDLMNEIDVDGNHQIEF 65 Query: 151 EEFCAVVGG 159 EF A++ Sbjct: 66 SEFLALMSR 74 >2N8Y-A nrPDB Length = 153 Score = 61.1 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 10/111 (9%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS---------LPELQQNPLVQRVIDIFD 63 S +++ F D D+SG+L EEF + + Q R++ I D Sbjct: 2 SSISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVD 61 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 + G V F+ FI+ +S+ + D ++ +F+I DK+ YI+ EL + Sbjct: 62 PNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITMDELRR 111 Score = 36.8 bits (84), Expect = 0.004, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 31/77 (40%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 S+ ++ + R +F +D D G + E L + + D Q + + + D Sbjct: 3 SISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDP 62 Query: 143 DGDGRISFEEFCAVVGG 159 + G ++F+ F + Sbjct: 63 NRLGVVTFQAFIDFMSR 79 >5H53-B nrPDB Length = 146 Score = 61.1 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 56/148 (37%), Gaps = 6/148 (4%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 +I+ + F +D + G + E+ + + + + +D + +G ++F F+ Sbjct: 3 QIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKEASGPINFTVFLT 62 Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTI 137 + D E + AF++ D + G I L ++L D Q+ + Sbjct: 63 MFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELLITQC-----DRFSQEEIKNMW 117 Query: 138 INADKDGDGRISFEEFCAVVGGLDIHKK 165 D G + ++ C V+ D + Sbjct: 118 AAFSPDVGGNVDYKNICYVITHGDAKDQ 145 >1O1A-B nrPDB Length = 145 Score = 61.1 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 46/114 (40%), Gaps = 1/114 (0%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPLVQRVIDIFDTDGNGEVDFK 73 FD EI+ + F +D + G + ++ + + + + +D + +G ++F Sbjct: 1 FDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEASGPINFT 60 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 F+ + D E + AF++ D D G I L ++L G + Sbjct: 61 VFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPEE 114 >1SR6-C nrPDB Length = 156 Score = 61.1 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 10/153 (6%) Query: 14 HFDADEIKRLGKRFKKLD--LDNSGSLSVEEFMSL-PELQQNPLVQRVIDIFDTDGNGE- 69 DEI L F+ D G++ + + L NP + V + T GE Sbjct: 2 KLSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRNEDVFAVGGTHKMGEK 61 Query: 70 -VDFKEFIEGVSQFSVKGD-KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 + F+EF+ AF+ +D + G+IS EL VL + G L D Sbjct: 62 SLPFEEFLPAYEGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTAL-GERLSDE 120 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFC-AVVGG 159 + +I+ T + D +G+ + +E+F V+ G Sbjct: 121 DVDEIIKLTDLQEDLEGN--VKYEDFVKKVMAG 151 >2K2A-A nrPDB Length = 70 Score = 60.7 bits (146), Expect = 3e-10, Method: Composition-based stats. Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 5/73 (6%) Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRI 148 +Q+LR AFR+YD + +GYIS + ++L L +T + +D I D DG G + Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILA-----ELDETLSSEDLDAMIDEIDADGSGTV 56 Query: 149 SFEEFCAVVGGLD 161 FEEF V+ G D Sbjct: 57 DFEEFMGVMTGGD 69 Score = 42.2 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 4/64 (6%) Query: 21 KRLGKRFKKLDLDNSGSLS----VEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 76 + L + F+ D + +G +S E L E + + +ID D DG+G VDF+EF+ Sbjct: 3 QELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFM 62 Query: 77 EGVS 80 ++ Sbjct: 63 GVMT 66 >4D1E-A nrPDB Length = 876 Score = 60.3 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 5/109 (4%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM----SLPELQQNPLVQRVIDIFDTD 65 +++ F D +G + E+F S+ R++ + D + Sbjct: 727 RDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPN 786 Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 G G V F+ FI+ +++ + D +++ +FRI DK YI EL + Sbjct: 787 GQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKP-YILAEELRR 834 Score = 36.5 bits (83), Expect = 0.005, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 31/69 (44%), Gaps = 5/69 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + R +F +D K+G + + + L M G +L + + + + D +G G ++F Sbjct: 739 EFRASFNHFDRRKNGLMDHEDFRACLISM-GYDLGEAEFA----RIMTLVDPNGQGTVTF 793 Query: 151 EEFCAVVGG 159 + F + Sbjct: 794 QSFIDFMTR 802 >1SJJ-A nrPDB Length = 863 Score = 60.3 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 5/109 (4%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM----SLPELQQNPLVQRVIDIFDTD 65 +++ F D +G + E+F S+ R++ I D + Sbjct: 714 RDAKGISQEQMNEFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPN 773 Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 G V F+ FI+ +S+ + D ++ +F+I DK+ YI+ EL + Sbjct: 774 RMGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITVDELRR 821 Score = 31.5 bits (70), Expect = 0.18, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 32/79 (40%), Gaps = 5/79 (6%) Query: 81 QFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA 140 + ++ + R +F +D K G + + L M G N+ + + +I+ Sbjct: 716 AKGISQEQMNEFRASFNHFDRKKTGMMDCEDFRACLISM-GYNMGEAEFARIMSIV---- 770 Query: 141 DKDGDGRISFEEFCAVVGG 159 D + G ++F+ F + Sbjct: 771 DPNRMGVVTFQAFIDFMSR 789 >5ZGM-A nrPDB Length = 110 Score = 60.3 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 11/115 (9%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDG 105 + ++ + + + + F G D+K F + V +KG E +++ F I D D+ G Sbjct: 3 MTKVLKADDINKAVSAF--KDPGTFDYKRFFQLVG---LKGKSEAQVKEVFEILDKDQSG 57 Query: 106 YISNGELFQVLKMMV--GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 +I EL VLK G +L DT+ + + + D D DG+I +EF +V Sbjct: 58 FIEEEELKSVLKGFSAHGRDLSDTETKAL----LAAGDSDHDGKIGADEFAKMVA 108 Score = 36.1 bits (82), Expect = 0.007, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 33/68 (48%), Gaps = 7/68 (10%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPEL-------QQNPLVQRVIDIFDTDGNGEVDFK 73 ++ + F+ LD D SG + EE S+ + + + ++ D+D +G++ Sbjct: 42 AQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTETKALLAAGDSDHDGKIGAD 101 Query: 74 EFIEGVSQ 81 EF + V+Q Sbjct: 102 EFAKMVAQ 109 Score = 35.3 bits (80), Expect = 0.013, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 36/87 (41%), Gaps = 4/87 (4%) Query: 36 GSLSVEEFMSLPELQ--QNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGD--KEQK 91 G+ + F L L+ V+ V +I D D +G ++ +E + FS G + + Sbjct: 23 GTFDYKRFFQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTE 82 Query: 92 LRFAFRIYDMDKDGYISNGELFQVLKM 118 + D D DG I E +++ Sbjct: 83 TKALLAAGDSDHDGKIGADEFAKMVAQ 109 >5B7X-A nrPDB Length = 156 Score = 59.2 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 11/144 (7%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSL-PELQQNPLVQRV---IDIFDTDGNGEVDFKEF 75 +++ F D D G + V++ +L L P V I F +G ++F Sbjct: 12 TQKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAIEGE-TFQIEQF 70 Query: 76 IEGVSQFSVKGDKEQ-KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVD 134 + + K D + KLR AF ++D DKDG I +L L VG+ + +++++ Sbjct: 71 ELIMEREQSKPDTREIKLRKAFEVFDQDKDGKIKASDLAHNLTT-VGDKMTKEEVEKVFS 129 Query: 135 KTIINADKDGDGRISFEEFCAVVG 158 I + D I F +V Sbjct: 130 ILGITMESD----IDLATFLKLVA 149 >1OQP-A nrPDB Length = 77 Score = 58.8 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 43/82 (52%), Gaps = 5/82 (6%) Query: 82 FSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINAD 141 S + D +++ AFR++D D G I+ +L +V K + G NL + +LQ+ I AD Sbjct: 1 GSGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKEL-GENLTEEELQE----MIAEAD 55 Query: 142 KDGDGRISFEEFCAVVGGLDIH 163 ++ D I +EF ++ + Sbjct: 56 RNDDNEIDEDEFIRIMKKTSLF 77 Score = 37.6 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFK 73 D + + K F+ D DNSG++++++ L E +Q +I D + + E+D Sbjct: 6 DSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDED 65 Query: 74 EFIEGVSQFSV 84 EFI + + S+ Sbjct: 66 EFIRIMKKTSL 76 Score = 26.4 bits (57), Expect = 6.6, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Query: 50 QQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISN 109 + + +FD D +G + K+ + V++ + E++L+ D + D I Sbjct: 6 DSREEILKAFRLFDDDNSGTITIKD-LRRVAKELGENLTEEELQEMIAEADRNDDNEIDE 64 Query: 110 GELFQVLKM 118 E +++K Sbjct: 65 DEFIRIMKK 73 >2W4G-C nrPDB Length = 145 Score = 58.8 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 27/146 (18%), Positives = 59/146 (40%), Gaps = 14/146 (9%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMSL-PELQQNPLVQRVIDIF-----DTDGNGEVD 71 DEI + F D +++ + + L QNP + I + ++ Sbjct: 1 DEINDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKIT 60 Query: 72 FKEFIEGVSQFSVKGD--KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 F+EF+ + + D + R++D + +G + EL VL + G + + ++ Sbjct: 61 FEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATL-GEKMTEEEV 119 Query: 130 QQIVDKTIINADKDGDGRISFEEFCA 155 + ++ +D +G I++E F Sbjct: 120 -----EELMKGQEDSNGCINYEAFVK 140 Score = 39.5 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 35/73 (47%), Gaps = 3/73 (4%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 D+ + AF ++D D I+ ++ +++ + G N + ++ +I+ + Sbjct: 1 DEINDFKEAFLLFDRTGDAKITLSQVGDIVRAL-GQNPTNAEINKILGNPSKE--EMNAK 57 Query: 147 RISFEEFCAVVGG 159 +I+FEEF ++ Sbjct: 58 KITFEEFLPMLQA 70 >3TS5-B nrPDB Length = 161 Score = 58.8 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 23/147 (15%), Positives = 56/147 (38%), Gaps = 6/147 (4%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDF 72 + ++ + + F +D + G + + + + + + + G ++F Sbjct: 15 ARLPQKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEAPGPLNF 74 Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQI 132 F+ S D E+ +R AF ++D ++ + +L N+ D + Sbjct: 75 TMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLL-----ENMGDNFNKDE 129 Query: 133 VDKTIINADKDGDGRISFEEFCAVVGG 159 + T A +G G+ + F A++ G Sbjct: 130 MRMTFKEAPVEG-GKFDYVRFVAMIKG 155 >2M97-A nrPDB Length = 69 Score = 58.0 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 5/73 (6%) Query: 88 KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR 147 E++L FRI+D D +G+I E +++ + G L D + VD+ ++D D +GR Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIR-LTGEQLTD----EDVDEIFGDSDTDKNGR 55 Query: 148 ISFEEFCAVVGGL 160 I F+EF ++ + Sbjct: 56 IDFDEFLKMMENV 68 Score = 43.4 bits (101), Expect = 4e-05, Method: Composition-based stats. Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN----PLVQRVIDIFDTDGNGEVDFKEFI 76 + L + F+ D D +G + EEF + L V + DTD NG +DF EF+ Sbjct: 3 EELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFL 62 Query: 77 EGV 79 + + Sbjct: 63 KMM 65 Score = 32.6 bits (73), Expect = 0.092, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Query: 51 QNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNG 110 + IFD DGNG +D +EF + + + + + ++ + F D DK+G I Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDII-RLTGEQLTDEDVDEIFGDSDTDKNGRIDFD 59 Query: 111 ELFQVLK 117 E ++++ Sbjct: 60 EFLKMME 66 >2KSZ-A nrPDB Length = 76 Score = 57.6 bits (138), Expect = 2e-09, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 4/72 (5%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEV 70 ++I + F D D G ++VEE + + L QNP +Q +I D DGNG + Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTI 63 Query: 71 DFKEFIEGVSQF 82 +F EF+ +++ Sbjct: 64 EFDEFLSLMAKK 75 Score = 56.1 bits (134), Expect = 7e-09, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 5/68 (7%) Query: 92 LRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFE 151 + AF ++D D DG I+ EL V++ L ++ + I D DG+G I F+ Sbjct: 12 FKEAFGLFDKDGDGCITVEELATVIRS-----LDQNPTEEELQDMISEVDADGNGTIEFD 66 Query: 152 EFCAVVGG 159 EF +++ Sbjct: 67 EFLSLMAK 74 >1ZMZ-A nrPDB Length = 98 Score = 57.6 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 38/75 (50%), Gaps = 4/75 (5%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQQNPL---VQRVIDIFDTDGNGE 69 ++ + + + F D D +G++ V+E ++ L P ++++I D +G G+ Sbjct: 24 ELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGK 83 Query: 70 VDFKEFIEGVSQFSV 84 ++F +F+ ++Q Sbjct: 84 MNFGDFLTVMTQKMS 98 Score = 53.8 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 5/75 (6%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 + +++Q++R AF ++D D G I EL ++ + K+ + K I DK+ Sbjct: 25 LTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEE-----IKKMISEIDKE 79 Query: 144 GDGRISFEEFCAVVG 158 G G+++F +F V+ Sbjct: 80 GTGKMNFGDFLTVMT 94 Score = 33.8 bits (76), Expect = 0.038, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 30/64 (46%), Gaps = 1/64 (1%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 ++ D+FD DG G +D KE + + K+++++ D + G ++ G+ Sbjct: 33 IREAFDLFDADGTGTIDVKELKVAMRALGFE-PKKEEIKKMISEIDKEGTGKMNFGDFLT 91 Query: 115 VLKM 118 V+ Sbjct: 92 VMTQ 95 >5PAL-A nrPDB Length = 109 Score = 57.3 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 11/115 (9%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDG 105 + ++ + + + I F G D+K F V +KG + +++ F I D D+ G Sbjct: 2 MTKVLKADDINKAISAF--KDPGTFDYKRFFHLVG---LKGKTDAQVKEVFEILDKDQSG 56 Query: 106 YISNGELFQVLKMMV--GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 +I EL VLK G +L DT+ + + D D DG+I +EF +V Sbjct: 57 FIEEEELKGVLKGFSAHGRDLNDTETK----ALLAAGDSDHDGKIGADEFAKMVA 107 Score = 35.3 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 35/87 (40%), Gaps = 4/87 (4%) Query: 36 GSLSVEEFMSLPELQQNPLVQ--RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGD--KEQK 91 G+ + F L L+ Q V +I D D +G ++ +E + FS G + + Sbjct: 22 GTFDYKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTE 81 Query: 92 LRFAFRIYDMDKDGYISNGELFQVLKM 118 + D D DG I E +++ Sbjct: 82 TKALLAAGDSDHDGKIGADEFAKMVAQ 108 Score = 35.3 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 7/68 (10%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPEL------QQNPLV-QRVIDIFDTDGNGEVDFK 73 ++ + F+ LD D SG + EE + + N + ++ D+D +G++ Sbjct: 41 AQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKALLAAGDSDHDGKIGAD 100 Query: 74 EFIEGVSQ 81 EF + V+Q Sbjct: 101 EFAKMVAQ 108 >5XND-A nrPDB Length = 114 Score = 57.3 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 5/92 (5%) Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 G D K+F + + G +++ AF I D DK G+I EL L+ + Sbjct: 28 GSFDHKKFFKACG---LSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALS 84 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + + D DGDG+I +EF A++ G Sbjct: 85 DAE--TKAFLKAGDSDGDGKIGIDEFAAMIKG 114 Score = 36.8 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 27/73 (36%), Gaps = 7/73 (9%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEE-------FMSLPELQQNPLVQRVIDIFDTDGN 67 + K F +D D SG + EE F + + + + D+DG+ Sbjct: 41 LSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDGD 100 Query: 68 GEVDFKEFIEGVS 80 G++ EF + Sbjct: 101 GKIGIDEFAAMIK 113 >2G9B-A nrPDB Length = 263 Score = 57.3 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 61/157 (38%), Gaps = 21/157 (13%) Query: 22 RLGKRFKKLDLDNSGSLSVEEFMSL----------PELQQNPLVQRVIDIFDTDGNGEVD 71 + + + D D SG L +E +L L+ +P ++ +D + +G++ Sbjct: 17 QFFEIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKTFVDQYGQRDDGKIG 76 Query: 72 FKEFIEGV--------SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV--- 120 E + + ++ +R YD D G+I EL LK ++ Sbjct: 77 IVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKA 136 Query: 121 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 + DT+L + D + D + DG++ E ++ Sbjct: 137 NKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 173 Score = 52.6 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 19/131 (14%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPE------------LQQNPLVQRVIDIFDTDGNG 68 + K ++K D D+SG + EE + + + ++ +FD++ +G Sbjct: 103 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 162 Query: 69 EVDFKEFIEGVSQFSVKGDKEQKLR-------FAFRIYDMDKDGYISNGELFQVLKMMVG 121 +++ E + K Q ++ AF +YD D +GYI EL +LK + Sbjct: 163 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 222 Query: 122 NNLKDTQLQQI 132 N ++ + I Sbjct: 223 KNKQELDINNI 233 >2N7L-C nrPDB Length = 141 Score = 56.9 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 49/86 (56%), Gaps = 6/86 (6%) Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDM-DKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 + I + + +++ + + AF I+ + +DG IS EL +V++ M+G N +LQ+ Sbjct: 16 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMR-MLGQNPTPEELQE 74 Query: 132 IVDKTIINADKDGDGRISFEEFCAVV 157 ++D+ D+DG G + F+EF ++ Sbjct: 75 MIDEV----DEDGSGTVDFDEFLVMM 96 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 5/81 (6%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLD-NSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDT 64 ++ F L GS+S +E + L QNP +Q +ID D Sbjct: 22 AAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDE 81 Query: 65 DGNGEVDFKEFIEGVSQFSVK 85 DG+G VDF EF+ + + Sbjct: 82 DGSGTVDFDEFLVMMVRXMKD 102 >1N2D-A nrPDB Length = 148 Score = 56.9 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 60/142 (42%), Gaps = 15/142 (10%) Query: 24 GKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIFDTDGNG------EVDFKEFI 76 F D G+++ + L + NP Q V DI + D + +D + Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGL 66 Query: 77 EGVSQFSVKGDKEQKLR---FAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 V++ + + K AF+++D + G +S G+L +L + G L D + V Sbjct: 67 IEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGL-GEKLTDAE----V 121 Query: 134 DKTIINADKDGDGRISFEEFCA 155 D+ + + D +G I +++F Sbjct: 122 DELLKGVEVDSNGEIDYKKFIE 143 Score = 36.1 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVD 71 + + K F+ D +++G +SV + + L V ++ + D NGE+D Sbjct: 78 TKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEID 137 Query: 72 FKEFIEGVSQ 81 +K+FIE V + Sbjct: 138 YKKFIEDVLR 147 >1OZS-A nrPDB Length = 73 Score = 56.5 bits (135), Expect = 5e-09, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 5/78 (6%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 +KG E++L FR++D + DGYI EL +L+ +T + +++ + + DK+ Sbjct: 1 MKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQAT-----GETITEDDIEELMKDGDKN 55 Query: 144 GDGRISFEEFCAVVGGLD 161 DGRI ++EF + G++ Sbjct: 56 NDGRIDYDEFLEFMKGVE 73 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 29/64 (45%), Gaps = 4/64 (6%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQ----QNPLVQRVIDIFDTDGNGEVDFKEFI 76 + L F+ D + G + +EE + + ++ ++ D + +G +D+ EF+ Sbjct: 7 EELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFL 66 Query: 77 EGVS 80 E + Sbjct: 67 EFMK 70 Score = 33.8 bits (76), Expect = 0.044, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 32/71 (45%), Gaps = 1/71 (1%) Query: 47 PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGY 106 + + + + +FD + +G +D +E ++ + Q + + E + + D + DG Sbjct: 1 MKGKSEEELSDLFRMFDKNADGYIDLEE-LKIMLQATGETITEDDIEELMKDGDKNNDGR 59 Query: 107 ISNGELFQVLK 117 I E + +K Sbjct: 60 IDYDEFLEFMK 70 >2L50-A nrPDB Length = 102 Score = 56.5 bits (135), Expect = 6e-09, Method: Composition-based stats. Identities = 20/55 (36%), Positives = 33/55 (60%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 IS ++L+ + + L DT ++ DK I N D + DGRISF+E+ ++GG+ Sbjct: 31 KISKSSFREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGI 85 Score = 26.1 bits (56), Expect = 7.4, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 16/41 (39%), Gaps = 1/41 (2%) Query: 41 EEFMSLPELQQN-PLVQRVIDIFDTDGNGEVDFKEFIEGVS 80 +E + N ++I D + +G + F E+ + Sbjct: 43 KELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEYWTLIG 83 >5VLN-A nrPDB Length = 120 Score = 56.1 bits (134), Expect = 6e-09, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 49/86 (56%), Gaps = 6/86 (6%) Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDM-DKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 + I + + +++ + + AF I+ + +DG IS EL +V++ M+G N +LQ+ Sbjct: 1 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMR-MLGQNPTPEELQE 59 Query: 132 IVDKTIINADKDGDGRISFEEFCAVV 157 ++D+ D+DG G + F+EF ++ Sbjct: 60 MIDEV----DEDGSGTVDFDEFLVMM 81 Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 5/81 (6%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLD-NSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDT 64 ++ F L GS+S +E + L QNP +Q +ID D Sbjct: 7 AAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDE 66 Query: 65 DGNGEVDFKEFIEGVSQFSVK 85 DG+G VDF EF+ + + Sbjct: 67 DGSGTVDFDEFLVMMVRSMKD 87 >1TNP-A nrPDB Length = 90 Score = 56.1 bits (134), Expect = 7e-09, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQR---VIDIFDTD 65 E + + I F D D G +S +E + + L QNP + +I+ D D Sbjct: 9 EARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDED 68 Query: 66 GNGEVDFKEFIEGVSQFSVK 85 G+G +DF+EF+ + + + Sbjct: 69 GSGTIDFEEFLVMMVRQMKE 88 Score = 56.1 bits (134), Expect = 8e-09, Method: Composition-based stats. Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 5/81 (6%) Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKT 136 + ++ + + + + AF ++D D G IS EL V++ M+G N +L D Sbjct: 7 QAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMR-MLGQNPTKEEL----DAI 61 Query: 137 IINADKDGDGRISFEEFCAVV 157 I D+DG G I FEEF ++ Sbjct: 62 IEEVDEDGSGTIDFEEFLVMM 82 Score = 32.6 bits (73), Expect = 0.098, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 31/82 (37%), Gaps = 1/82 (1%) Query: 42 EFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDM 101 E + + + D+FD DG G++ KE + + + +++L D Sbjct: 9 EARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVM-RMLGQNPTKEELDAIIEEVDE 67 Query: 102 DKDGYISNGELFQVLKMMVGNN 123 D G I E ++ + + Sbjct: 68 DGSGTIDFEEFLVMMVRQMKED 89 >3JBH-C nrPDB Length = 156 Score = 55.7 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 33/148 (22%), Positives = 63/148 (42%), Gaps = 10/148 (6%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-PELQQNPLVQRVIDIFDTDGNGE--VD 71 A E+++ + F+ D + G + + L L P + V +D GE + Sbjct: 4 LKAAEVEKAREHFEIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKNGGSDKRGEKKLT 63 Query: 72 FKEFIEGVSQFSVKGD--KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 +EF+ SQ + + + ++YD ++G + EL VL + G L D + Sbjct: 64 LEEFLPIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSL-GERLTDIEC 122 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVV 157 ++I+ D+D DG + +E F + Sbjct: 123 EEIM----RVCDEDDDGFLKYEPFVKTI 146 Score = 31.8 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 6/82 (7%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 +K + +K R F IYD + +G I +L +L+ + D + + K +DK Sbjct: 3 DLKAAEVEKAREHFEIYDWEGEGKIDARDLGDLLRSL------DCKPTLAMVKKNGGSDK 56 Query: 143 DGDGRISFEEFCAVVGGLDIHK 164 G+ +++ EEF + + K Sbjct: 57 RGEKKLTLEEFLPIFSQIKKEK 78 >2EC6-B nrPDB Length = 133 Score = 55.7 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 23/139 (16%), Positives = 54/139 (38%), Gaps = 6/139 (4%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGV 79 ++ + + F +D + G + + + + + + G ++F F+ Sbjct: 1 MQEMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPDDKELTAMLKEAPGPLNFTMFLSIF 60 Query: 80 SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIIN 139 S D E+ +R AF ++D D ++ + +L N+ D + + T Sbjct: 61 SDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDLL-----ENMGDNFNKDEMRMTFKE 115 Query: 140 ADKDGDGRISFEEFCAVVG 158 A +G G+ + F A++ Sbjct: 116 APVEG-GKFDYVRFVAMIK 133 >1TRF-A nrPDB Length = 76 Score = 55.7 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + AF ++D D G IS EL V++ M+G N +L D I D+DG G I F Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMR-MLGQNPTKEEL----DAIIEEVDEDGSGTIDF 64 Query: 151 EEFCAVV 157 EEF ++ Sbjct: 65 EEFLVMM 71 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 4/74 (5%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQR---VIDIFDTDGNGEV 70 + I F D D G +S +E + + L QNP + +I+ D DG+G + Sbjct: 3 LSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTI 62 Query: 71 DFKEFIEGVSQFSV 84 DF+EF+ + + Sbjct: 63 DFEEFLVMMVRQMK 76 Score = 31.8 bits (71), Expect = 0.14, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 + D+FD DG G++ KE + + + +++L D D G I E + Sbjct: 12 KAAFDMFDADGGGDISTKELGTVM-RMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVM 70 Query: 116 L 116 + Sbjct: 71 M 71 >6IIE-A nrPDB Length = 93 Score = 55.3 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 4/77 (5%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ-VLKMMVGNNLKD---TQLQQIVDKTII 138 G E KL F F++YD D++G + + E+ + +L+MM D ++L+ I+ + + Sbjct: 2 MEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMK 61 Query: 139 NADKDGDGRISFEEFCA 155 D DG G +S E+ Sbjct: 62 EIDYDGSGSVSQAEWVR 78 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 29/70 (41%), Gaps = 13/70 (18%) Query: 22 RLGKRFKKLDLDNSGSLSVEE----FMSLPELQQN---------PLVQRVIDIFDTDGNG 68 +L FK D D +G L E + + + + P++Q ++ D DG+G Sbjct: 10 KLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSG 69 Query: 69 EVDFKEFIEG 78 V E++ Sbjct: 70 SVSQAEWVRA 79 >1RTP-1 nrPDB Length = 109 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 7/114 (6%) Query: 45 SLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKD 104 S+ +L +++ I F + D K+F + V D +K+ F I D DK Sbjct: 1 SMTDLLSAEDIKKAIGAFTAADS--FDHKKFFQMVGLKKKSADDVKKV---FHILDKDKS 55 Query: 105 GYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 G+I EL +LK ++ +D ++ + DKDGDG+I EEF +V Sbjct: 56 GFIEEDELGSILKGF-SSDARDLSAKE-TKTLMAAGDKDGDGKIGVEEFSTLVA 107 Score = 33.0 bits (74), Expect = 0.058, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 7/65 (10%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSLPEL-------QQNPLVQRVIDIFDTDGNGEVDFKEFI 76 K F LD D SG + +E S+ + + ++ D DG+G++ +EF Sbjct: 44 KKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFS 103 Query: 77 EGVSQ 81 V++ Sbjct: 104 TLVAE 108 Score = 32.6 bits (73), Expect = 0.089, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 43/112 (38%), Gaps = 9/112 (8%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN--PLVQRVIDIFDTDGNG 68 M A++IK+ F D S ++F + L++ V++V I D D +G Sbjct: 2 MTDLLSAEDIKKAIGAFTAAD-----SFDHKKFFQMVGLKKKSADDVKKVFHILDKDKSG 56 Query: 69 EVDFKEFIEGVSQFSVKGD--KEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 ++ E + FS ++ + D D DG I E ++ Sbjct: 57 FIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFSTLVAE 108 >3AKA-A nrPDB Length = 166 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 53/156 (33%), Gaps = 32/156 (20%) Query: 22 RLGKRFKKLDLDNSGSLSVEEF-------------------MSLPELQQNPLVQRVIDIF 62 R+ RF D D +G + +F L Q + I Sbjct: 5 RIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGIA 64 Query: 63 DTDGNGEVDFKEFIE-GVSQFSVKGDKEQK-----LRFAFRIYDMDKDGYISNGELFQVL 116 D DG+ + +EF+ V + K D+ + L A + D D DG ++ + + L Sbjct: 65 DRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTARAL 124 Query: 117 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 + + + D DGDG++ E Sbjct: 125 TAFGV-------PEDLARQAAAALDTDGDGKVGETE 153 Score = 42.6 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 30/77 (38%), Gaps = 10/77 (12%) Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT----------QLQQIVDKTII 138 E+++ F +D D +G+I + K ++ + + Sbjct: 3 ERRIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAG 62 Query: 139 NADKDGDGRISFEEFCA 155 AD+DGD RI+ EEF Sbjct: 63 IADRDGDQRITREEFVT 79 Score = 40.3 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 14/93 (15%) Query: 31 DLDNSGSLSVEEF--MSLPELQ---------QNPLVQRVIDIFDTDGNGEVDFKEFIEGV 79 D D ++ EEF ++ L+ P + + + DTDG+G V + + Sbjct: 65 DRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTARAL 124 Query: 80 SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 + F G E R A D D DG + E+ Sbjct: 125 TAF---GVPEDLARQAAAALDTDGDGKVGETEI 154 >1C7W-A nrPDB Length = 81 Score = 54.6 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 42/76 (55%), Gaps = 4/76 (5%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 V+ D E+++ AF+++D + DG I E +++ + L D ++++ + + AD+D Sbjct: 2 VRQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKE----ADED 57 Query: 144 GDGRISFEEFCAVVGG 159 G+G I EF ++ Sbjct: 58 GNGVIDIPEFMDLIKK 73 Score = 39.9 bits (92), Expect = 5e-04, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 31/71 (43%) Query: 48 ELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYI 107 + R +FD +G+G +DF EF + + + + ++ A + D D +G I Sbjct: 3 RQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVI 62 Query: 108 SNGELFQVLKM 118 E ++K Sbjct: 63 DIPEFMDLIKK 73 Score = 37.2 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLP-ELQQNPL----VQRVIDIFDTDGNGEVD 71 D+ + + + FK D + G + +EF + ++ + PL V+ + D DGNG +D Sbjct: 4 QDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVID 63 Query: 72 FKEFIEGVSQ 81 EF++ + + Sbjct: 64 IPEFMDLIKK 73 Score = 30.7 bits (68), Expect = 0.36, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 17/31 (54%) Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 ++ + + D +GDG I F+EF ++ + Sbjct: 7 EEEILRAFKVFDANGDGVIDFDEFKFIMQKV 37 >4OCI-A nrPDB Length = 146 Score = 54.6 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 29/136 (21%), Positives = 56/136 (41%), Gaps = 7/136 (5%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSL-PELQQNPLVQRVIDIFDTDGNGE-VDFKEFIEG 78 + L + F D D G L++ EF SL L + ++++ + ++ F Sbjct: 6 EDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMETSAIASTYNSNSKVRGMSYELFTSC 65 Query: 79 VSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII 138 SQ K + +++ A + D DK G+I EL ++L + + D Q+ + Sbjct: 66 FSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRIL-----STIGDNMEQKEITDLFT 120 Query: 139 NADKDGDGRISFEEFC 154 D G + ++F Sbjct: 121 FMGIDEQGVVKVDDFI 136 Score = 30.7 bits (68), Expect = 0.34, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 20/33 (60%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM 119 + L+ +F ++D D DGY++ E +++++ Sbjct: 3 KHNEDLKESFLLFDGDGDGYLTLNEFESLVRVL 35 Score = 26.1 bits (56), Expect = 8.2, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 17/27 (62%) Query: 131 QIVDKTIINADKDGDGRISFEEFCAVV 157 + + ++ + D DGDG ++ EF ++V Sbjct: 6 EDLKESFLLFDGDGDGYLTLNEFESLV 32 >5Z1Q-A nrPDB Length = 95 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 38/79 (48%), Gaps = 4/79 (5%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQ---QNPLVQRVIDIFDTD 65 + ++ + + + F D + +GS+ E ++ L + P + +++ +D + Sbjct: 16 RVRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDRE 75 Query: 66 GNGEVDFKEFIEGVSQFSV 84 GNG + F +F++ +++ Sbjct: 76 GNGYIGFDDFLDIMTEKIK 94 Score = 46.9 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 47/78 (60%), Gaps = 5/78 (6%) Query: 81 QFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA 140 + + +++Q+++ AF ++D +K G I EL ++ + G ++K ++ +++++ Sbjct: 18 RQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRAL-GFDVKKPEILELMNEY---- 72 Query: 141 DKDGDGRISFEEFCAVVG 158 D++G+G I F++F ++ Sbjct: 73 DREGNGYIGFDDFLDIMT 90 Score = 36.8 bits (84), Expect = 0.004, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 27/64 (42%), Gaps = 1/64 (1%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 ++ D+FDT+ G +D+ E + + ++ YD + +GYI + Sbjct: 29 IKEAFDLFDTNKTGSIDYHELKVAMRALGFDVK-KPEILELMNEYDREGNGYIGFDDFLD 87 Query: 115 VLKM 118 ++ Sbjct: 88 IMTE 91 >1YX7-A nrPDB Length = 83 Score = 53.4 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 1/69 (1%) Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNN-LKDTQLQQIVDKTIINADKDGD 145 + +L AF+ D + DGY++ EL + + L ++++ K I ADK+ D Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSD 63 Query: 146 GRISFEEFC 154 G+IS EEF Sbjct: 64 GKISKEEFL 72 Score = 39.5 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 31/73 (42%), Gaps = 10/73 (13%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMS----------LPELQQNPLVQRVIDIFDTDGNGEV 70 L FKKLD + G ++ E + L + + ++I + D + +G++ Sbjct: 7 AELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGKI 66 Query: 71 DFKEFIEGVSQFS 83 +EF+ ++ Sbjct: 67 SKEEFLNANAELL 79 Score = 29.1 bits (64), Expect = 0.87, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 19/41 (46%) Query: 129 LQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVD 169 ++ ++ D +GDG ++ E + LD +K + D Sbjct: 5 VKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKD 45 >3I5I-C nrPDB Length = 159 Score = 53.0 bits (126), Expect = 7e-08, Method: Composition-based stats. Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 11/155 (7%) Query: 13 SHFDADEIKRLGKRFKKLD--LDNSGSLSVEEFMSLPE-LQQNPLVQRVIDIFDTDGNGE 69 S DEI+ + + F D G + + L L NP +V T GE Sbjct: 1 SQLTKDEIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQHGGTKKMGE 60 Query: 70 VDFK-EFIEGVSQFSVKGDK---EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 +K E I + + D + AF+ +D + G IS+ E+ VLK M+G + Sbjct: 61 KAYKLEEILPIYEEMSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLK-MLGERIT 119 Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEFC-AVVGG 159 + Q I T + +D DG I +E+ V+ G Sbjct: 120 EDQCNDIF--TFCDIREDIDGNIKYEDLMKKVMAG 152 Score = 29.1 bits (64), Expect = 0.90, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 29/74 (39%), Gaps = 6/74 (8%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIFDT---- 64 EM S + FK D + G +S E + L L + + DIF Sbjct: 74 EMSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKMLGERITEDQCNDIFTFCDIR 133 Query: 65 -DGNGEVDFKEFIE 77 D +G + +++ ++ Sbjct: 134 EDIDGNIKYEDLMK 147 >5OTJ-D nrPDB Length = 110 Score = 52.6 bits (125), Expect = 7e-08, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 6/66 (9%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 + F+ +D + DG IS EL L+ + + + V + + D DGDG I Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLGSTSADE------VQRMMAEIDTDGDGFID 56 Query: 150 FEEFCA 155 F EF + Sbjct: 57 FNEFIS 62 Score = 46.1 bits (108), Expect = 7e-06, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 24 GKRFKKLDLDNSGSLSVEEFMS-LPELQQN--PLVQRVIDIFDTDGNGEVDFKEFIEGVS 80 + FK+ D + G +S+ E L L VQR++ DTDG+G +DF EFI + Sbjct: 6 ERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISFCN 65 Query: 81 QFSVKGDKEQKL 92 K+ Sbjct: 66 ANPGLMKDVAKV 77 Score = 36.8 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 27/71 (38%), Gaps = 2/71 (2%) Query: 53 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 ++R+ FDT+G+G++ E + + E + A D D DG+I E Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMA--EIDTDGDGFIDFNEF 60 Query: 113 FQVLKMMVGNN 123 G Sbjct: 61 ISFCNANPGLM 71 >1RK9-A nrPDB Length = 110 Score = 52.6 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 7/115 (6%) Query: 44 MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDK 103 MS+ +L +++ + F + D K+F + V D +K+ F + D DK Sbjct: 1 MSMTDLLNAEDIKKAVGAFSATDS--FDHKKFFQMVGLKKKSADDVKKV---FHMLDKDK 55 Query: 104 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 G+I EL +LK + + + DKDGDG+I +EF +V Sbjct: 56 SGFIEEDELGFILKGFSPDAR--DLSAKETKMLMAAGDKDGDGKIGVDEFSTLVA 108 Score = 31.8 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSLPEL-------QQNPLVQRVIDIFDTDGNGEVDFKEFI 76 K F LD D SG + +E + + + ++ D DG+G++ EF Sbjct: 45 KKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFS 104 Query: 77 EGVSQ 81 V++ Sbjct: 105 TLVAE 109 Score = 30.7 bits (68), Expect = 0.35, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 45/114 (39%), Gaps = 9/114 (7%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN--PLVQRVIDIFDTDG 66 + M +A++IK+ F D S ++F + L++ V++V + D D Sbjct: 1 MSMTDLLNAEDIKKAVGAFSATD-----SFDHKKFFQMVGLKKKSADDVKKVFHMLDKDK 55 Query: 67 NGEVDFKEFIEGVSQFSVKGD--KEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 +G ++ E + FS ++ + D D DG I E ++ Sbjct: 56 SGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAE 109 >2M8U-A nrPDB Length = 77 Score = 52.6 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 35/75 (46%), Gaps = 5/75 (6%) Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 + + ++ AF+++D D +GY++ L +VL + D +++ I AD Sbjct: 4 MNHINTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADE-----IEEMIYEADP 58 Query: 143 DGDGRISFEEFCAVV 157 G + +E F ++ Sbjct: 59 QNSGYVQYETFVGML 73 Score = 36.8 bits (84), Expect = 0.004, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 27/59 (45%), Gaps = 4/59 (6%) Query: 25 KRFKKLDLDNSGSLSVEEFMS----LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGV 79 + FK D D +G ++V+ L ++ ++ +I D +G V ++ F+ + Sbjct: 15 EAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSGYVQYETFVGML 73 >2LVV-A nrPDB Length = 226 Score = 52.3 bits (124), Expect = 9e-08, Method: Composition-based stats. Identities = 34/154 (22%), Positives = 55/154 (35%), Gaps = 23/154 (14%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMS----LPELQQNPL--VQRVIDIFDTDGN-- 67 DA+ R + FK+ D + +G L E + + +L + V FD + Sbjct: 46 DAESKSRRIELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLG 105 Query: 68 ------GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV- 120 GE D EF+E D + L F D D + E + L + Sbjct: 106 NKVKGVGEEDLVEFLEFRLMLCYIYDIFE-LTVMFDTMDKDGSLLLELQEFKEALPKLKE 164 Query: 121 -GNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 G ++ D D +G G ++F+EF Sbjct: 165 WGVDITDATT------VFNEIDTNGSGVVTFDEF 192 Score = 27.6 bits (60), Expect = 2.5, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 25/90 (27%), Gaps = 11/90 (12%) Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 E I + + + F+ +D + G + +VL G D + Sbjct: 35 ERIRCAIPRDKDAESKSRRIELFKQFDTNGTGKLG---FREVLDGCYGILKLDEFTTHLP 91 Query: 134 DKTIINADKDGD--------GRISFEEFCA 155 D DK D G EF Sbjct: 92 DIVQRAFDKAKDLGNKVKGVGEEDLVEFLE 121 >2JOJ-A nrPDB Length = 77 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 38/77 (49%), Gaps = 4/77 (5%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFM-SLPELQ---QNPLVQRVIDIFDTDGNGEV 70 ++ + + + F D + +GS+ E ++ L + P + +++ +D +GNG + Sbjct: 1 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYI 60 Query: 71 DFKEFIEGVSQFSVKGD 87 F +F++ +++ D Sbjct: 61 GFDDFLDIMTEKIKNRD 77 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 46/75 (61%), Gaps = 5/75 (6%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 + +++Q+++ AF ++D +K G I EL ++ + G ++K ++ +++++ D++ Sbjct: 1 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRAL-GFDVKKPEILELMNEY----DRE 55 Query: 144 GDGRISFEEFCAVVG 158 G+G I F++F ++ Sbjct: 56 GNGYIGFDDFLDIMT 70 Score = 35.3 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 27/64 (42%), Gaps = 1/64 (1%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 ++ D+FDT+ G +D+ E + + ++ YD + +GYI + Sbjct: 9 IKEAFDLFDTNKTGSIDYHELKVAMRALGFDVK-KPEILELMNEYDREGNGYIGFDDFLD 67 Query: 115 VLKM 118 ++ Sbjct: 68 IMTE 71 >4GJF-A nrPDB Length = 89 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 48/86 (55%), Gaps = 6/86 (6%) Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDM-DKDGYISNGELFQVLKMMVGNNLKDTQLQQ 131 + I + + +++ + + AF I+ +DG IS EL +V++ M+G N +LQ+ Sbjct: 1 MDDIYKAAVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMR-MLGQNPTPEELQE 59 Query: 132 IVDKTIINADKDGDGRISFEEFCAVV 157 ++D+ D+DG G + F+EF ++ Sbjct: 60 MIDEV----DEDGSGTVDFDEFLVMM 81 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 31/81 (38%), Gaps = 5/81 (6%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLD-NSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDT 64 ++ F G +S +E + L QNP +Q +ID D Sbjct: 7 AAVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDE 66 Query: 65 DGNGEVDFKEFIEGVSQFSVK 85 DG+G VDF EF+ + + Sbjct: 67 DGSGTVDFDEFLVMMVRCMKD 87 >1QX2-A nrPDB Length = 76 Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 5/78 (6%) Query: 86 GDKEQKLRFAFRIYD-MDKD-GYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 ++++ AF ++ + D IS EL V++ + + LK +D+ I DK+ Sbjct: 1 MKSPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMST---LDEMIEEVDKN 57 Query: 144 GDGRISFEEFCAVVGGLD 161 GDG +SFEEF ++ + Sbjct: 58 GDGEVSFEEFLVMMKKIS 75 Score = 37.2 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 7/74 (9%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPE------LQQNPLVQRVIDIFDTDGNGE 69 +EIK + F + D + +S EE + + L+ + +I+ D +G+GE Sbjct: 3 SPEEIKGAFEVFAAKEGDPN-QISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGE 61 Query: 70 VDFKEFIEGVSQFS 83 V F+EF+ + + S Sbjct: 62 VSFEEFLVMMKKIS 75 >2Q4U-A nrPDB Length = 272 Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 55/154 (35%), Gaps = 26/154 (16%) Query: 9 LEMCSHFDADEIKRLGKRFK-KLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGN 67 L+ + ++++ K F D G L +EE ++ Sbjct: 44 LQPKDKITDERVQQIKKSFMSAYDATFDGRLQIEELANM--------------------- 82 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKD- 126 + +E + + D + +R YD D GYIS EL LK + + K Sbjct: 83 -ILPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKKI 141 Query: 127 --TQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 +L + D + DK+ DGR+ + ++ Sbjct: 142 PPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILA 175 Score = 36.8 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 24/148 (16%), Positives = 54/148 (36%), Gaps = 25/148 (16%) Query: 9 LEMCSHFDADEIKRLGKRFKK-LDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGN 67 L+ +++ K D + G L + + + LQ+N L+Q +D Sbjct: 135 LQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDA------ 188 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGE---LFQVLKMMVGNNL 124 S + ++++ F YD+ + G + E + + +V ++ Sbjct: 189 ---------------SSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVKDMMELVRPSI 233 Query: 125 KDTQLQQIVDKTIINADKDGDGRISFEE 152 L + + + + D + DG+I E Sbjct: 234 SGGDLDKFRECLLTHCDMNKDGKIQKSE 261 Score = 36.5 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 5/64 (7%) Query: 99 YDMDKDGYISNGELFQVLKMMV-----GNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 +D D +GYI EL + M+ + + D ++QQI + D DGR+ EE Sbjct: 20 FDADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFDGRLQIEEL 79 Query: 154 CAVV 157 ++ Sbjct: 80 ANMI 83 Score = 29.9 bits (66), Expect = 0.56, Method: Composition-based stats. Identities = 25/111 (22%), Positives = 43/111 (38%), Gaps = 15/111 (13%) Query: 57 RVIDIFDTDGNGEV---DFKEFIEGVSQFSVKGD-----KEQKLRFAF-RIYDMDKDGYI 107 ++ FD D NG + + +F + + D + Q+++ +F YD DG + Sbjct: 15 QIWQHFDADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFDGRL 74 Query: 108 SNGELFQVLKMMVGNNLKDTQLQQIVD------KTIINADKDGDGRISFEE 152 EL ++ N L + + +D K D D G IS E Sbjct: 75 QIEELANMILPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAE 125 >3PAT-A nrPDB Length = 110 Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 10/107 (9%) Query: 55 VQRVIDIFDT-DGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113 + D G + K+F V ++ + +K+ F+ D D G+I EL Sbjct: 9 ADDIKKALDAVKAEGSFNHKKFFALVGLKAMSANDVKKV---FKAIDADASGFIEEEELK 65 Query: 114 QVLKMMV--GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 VLK G +L D + + + ADKDGDG+I +EF +V Sbjct: 66 FVLKSFAADGRDLTDAETK----AFLKAADKDGDGKIGIDEFETLVH 108 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 26/65 (40%), Gaps = 7/65 (10%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSLP-------ELQQNPLVQRVIDIFDTDGNGEVDFKEFI 76 K FK +D D SG + EE + + + + D DG+G++ EF Sbjct: 45 KKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGIDEFE 104 Query: 77 EGVSQ 81 V + Sbjct: 105 TLVHE 109 >1S6J-A nrPDB Length = 87 Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 4/75 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDG 66 M +EI L + FK +D DNSG+++ +E + + L ++ ++D D D Sbjct: 13 MAERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDK 72 Query: 67 NGEVDFKEFIEGVSQ 81 +G +D+ EFI Sbjct: 73 SGTIDYGEFIAATVH 87 Score = 43.8 bits (102), Expect = 3e-05, Method: Composition-based stats. Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 5/64 (7%) Query: 92 LRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFE 151 L+ F++ D D G I+ EL LK VG+ L +++++ ++D AD D G I + Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLKR-VGSELMESEIKDLMD----AADIDKSGTIDYG 79 Query: 152 EFCA 155 EF A Sbjct: 80 EFIA 83 >1H4B-A nrPDB Length = 84 Score = 50.3 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 88 KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR 147 + + F+ +D + DG IS EL + LK + + V + D DGDG Sbjct: 7 DKAERERIFKRFDANGDGKISAAELGEALKTLGSITPDE------VKHMMAEIDTDGDGF 60 Query: 148 ISFEEF 153 ISF+EF Sbjct: 61 ISFQEF 66 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN---PLVQRVIDIFDTDGNGEVDFKEF 75 + + FK+ D + G +S E + + V+ ++ DTDG+G + F+EF Sbjct: 7 DKAERERIFKRFDANGDGKISAAELGEALKTLGSITPDEVKHMMAEIDTDGDGFISFQEF 66 Score = 36.1 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 2/66 (3%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 +R+ FD +G+G++ E E + E K A D D DG+IS E Sbjct: 12 ERIFKRFDANGDGKISAAELGEALKTLGSITPDEVKHMMA--EIDTDGDGFISFQEFTDF 69 Query: 116 LKMMVG 121 + G Sbjct: 70 GRANRG 75 >2PMY-A nrPDB Length = 91 Score = 49.9 bits (118), Expect = 5e-07, Method: Composition-based stats. Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-PELQQNP-LVQRVIDIFDTDGNGEVDFK 73 D +E+ RL F D + SG L EEF +L EL+ P + V D D +G + F+ Sbjct: 22 DGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDGAITFQ 81 Query: 74 EFIEG 78 EF G Sbjct: 82 EFARG 86 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 28/79 (35%), Gaps = 9/79 (11%) Query: 79 VSQFSVKGDKEQ--KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKT 136 + GD E+ +LR F D ++ G + E + + + Sbjct: 14 LYFQGADGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPAD-------AEAV 66 Query: 137 IINADKDGDGRISFEEFCA 155 D D DG I+F+EF Sbjct: 67 FQRLDADRDGAITFQEFAR 85 >2OPO-A nrPDB Length = 86 Score = 49.9 bits (118), Expect = 5e-07, Method: Composition-based stats. Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 6/58 (10%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153 F+ +D + DG IS+ EL LK + + V + + D DGDG ISF+EF Sbjct: 17 FKRFDTNGDGKISSSELGDALKTLGSVTPDE------VRRMMAEIDTDGDGFISFDEF 68 Score = 43.0 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 34/85 (40%), Gaps = 3/85 (3%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN---PLVQRVIDIFDTDGN 67 M + +I + FK+ D + G +S E + + V+R++ DTDG+ Sbjct: 1 MAAEDTPQDIADRERIFKRFDTNGDGKISSSELGDALKTLGSVTPDEVRRMMAEIDTDGD 60 Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKL 92 G + F EF + K+ Sbjct: 61 GFISFDEFTDFARANRGLVKDVSKI 85 Score = 35.7 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 28/66 (42%), Gaps = 2/66 (3%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 +R+ FDT+G+G++ E + + E + A D D DG+IS E Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLGSVTPDEVRRMMA--EIDTDGDGFISFDEFTDF 71 Query: 116 LKMMVG 121 + G Sbjct: 72 ARANRG 77 >2LVK-A nrPDB Length = 77 Score = 49.9 bits (118), Expect = 5e-07, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 6/66 (9%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 + F+ +D + DG IS EL L+ + + + V + + D DGDG I Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGSTSADE------VQRMMAEIDTDGDGFID 55 Query: 150 FEEFCA 155 F EF + Sbjct: 56 FNEFIS 61 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 24 GKRFKKLDLDNSGSLSVEEFMS-LPELQQN--PLVQRVIDIFDTDGNGEVDFKEFIEGVS 80 + FK+ D + G +S+ E L L VQR++ DTDG+G +DF EFI + Sbjct: 5 ERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISFCN 64 Query: 81 QFSVKGDKEQKL 92 K+ Sbjct: 65 ANPGLMKDVAKV 76 Score = 34.9 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 27/71 (38%), Gaps = 2/71 (2%) Query: 53 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 ++R+ FDT+G+G++ E + + E + A D D DG+I E Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMA--EIDTDGDGFIDFNEF 59 Query: 113 FQVLKMMVGNN 123 G Sbjct: 60 ISFCNANPGLM 70 >4P5X-A nrPDB Length = 315 Score = 49.6 bits (117), Expect = 6e-07, Method: Composition-based stats. Identities = 18/115 (15%), Positives = 42/115 (36%), Gaps = 12/115 (10%) Query: 26 RFKKLDLDNSGSLSVEEFMSLPELQ-------QNPLVQRVIDIFDTDGNGEVDFKEFIEG 78 F+ D +G ++ E + N + + F + +++ EF + Sbjct: 98 AFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQF 157 Query: 79 VSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 + + + + R AF + D K G IS + ++ + + L + +V Sbjct: 158 LQELQL-----EHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLV 207 Score = 46.9 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 20/152 (13%), Positives = 56/152 (36%), Gaps = 16/152 (10%) Query: 22 RLGKRFKKL---DLDNSGSLSVEEFMSLPELQQNP------LVQRVIDIFDTDGNGEVDF 72 L F + ++D ++ E+F+ N +VQ + + D +G + + Sbjct: 19 ELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISY 78 Query: 73 KEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ-Q 131 +EF+ S + AF+++D +G ++ + ++ + ++ + Sbjct: 79 QEFLAFESVLCA---PDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCE 135 Query: 132 IVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 + + +++ EF + L + Sbjct: 136 FIRLHFG---HNRKKHLNYTEFTQFLQELQLE 164 Score = 33.0 bits (74), Expect = 0.062, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 39/95 (41%), Gaps = 6/95 (6%) Query: 77 EGVSQFSVKGDKEQKLRFAFRIY---DMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 E V + K +LR F Y ++D + Y++ + Q + + + +IV Sbjct: 5 EAVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNP---KIV 61 Query: 134 DKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVV 168 AD+ DG IS++EF A L M + Sbjct: 62 QLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFI 96 >1JF0-A nrPDB Length = 195 Score = 49.6 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 70/172 (40%), Gaps = 30/172 (17%) Query: 6 SYPLEMCSHFDADE-IKRLGKRFKKLDLDNSGSLSVEEFMSL------PELQQNPLV--- 55 Y +++ + FD + IKR F LD++ +G ++++E +S L P Sbjct: 4 KYAVKLQTDFDNPKWIKRHKFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQR 63 Query: 56 -QRVIDIFDT----DGNGEVDFKEFIEG--------VSQFSVKGDK--EQKLRFAFRIYD 100 Q ++ F + E F EF+EG +++++ + F I+D Sbjct: 64 HQDCVEAFFRGCGLEYGKETKFPEFLEGWKNLANADLAKWARNEPTLIREWGDAVFDIFD 123 Query: 101 MDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 D G I+ E ++ + G + + ++ T + D D G + +E Sbjct: 124 KDGSGTITLDE-WKAYGRISGISPSEEDCEK----TFQHCDLDNSGELDVDE 170 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 27/62 (43%), Gaps = 1/62 (1%) Query: 53 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 V DIFD DG+G + E+ + + S E+ F+ D+D G + E+ Sbjct: 113 EWGDAVFDIFDKDGSGTITLDEW-KAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDEM 171 Query: 113 FQ 114 + Sbjct: 172 TR 173 >5ZH6-A nrPDB Length = 107 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 5/92 (5%) Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 G + K F + + L F I D D+ G+I EL L+ + Sbjct: 21 GSFNHKTFFVTSG---LTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELD 77 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + + + + D D DG+I +EF A+V Sbjct: 78 ETE--TNAFLAAGDSDHDGKIGVDEFKAMVKA 107 Score = 32.6 bits (73), Expect = 0.090, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 28/77 (36%), Gaps = 9/77 (11%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM--------SLPELQQNPLVQRVIDIFDT 64 S L K F LD D SG + V+E + EL + + D+ Sbjct: 32 SGLTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLA-AGDS 90 Query: 65 DGNGEVDFKEFIEGVSQ 81 D +G++ EF V Sbjct: 91 DHDGKIGVDEFKAMVKA 107 >4P5W-A nrPDB Length = 411 Score = 48.8 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 60/155 (38%), Gaps = 16/155 (10%) Query: 19 EIKRLGKRFKK---LDLDNSGSLSVEEFMS-----LPELQQNP-LVQRVIDIFDTDGNGE 69 + L F K ++ + +S +F++ E Q NP V+ + + D +G Sbjct: 35 DPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGL 94 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL-KMMVGNNLKDTQ 128 + F+EF+ S + AF+++D G ++ ++ QV + + ++ Sbjct: 95 ISFQEFVAFESVLCA---PDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIHQHIPFNW 151 Query: 129 LQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 + V K +++ EF + + + Sbjct: 152 DSEFVQLHFGKERKRH---LTYAEFTQFLLEIQLE 183 Score = 30.3 bits (67), Expect = 0.43, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 37/105 (35%), Gaps = 8/105 (7%) Query: 61 IFDTDGNGEVDFKEFI-EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM 119 + +G + +F+ ++ F + + + D KDG IS E ++ Sbjct: 48 SIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVL 107 Query: 120 VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHK 164 + DK G G ++FE+ V G IH+ Sbjct: 108 CA-------PDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIHQ 145 Score = 28.8 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 33/93 (35%), Gaps = 6/93 (6%) Query: 77 EGVSQFSVKGDKEQKLRFAFRIY---DMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 K +LR F Y + + + ++S + + G + + + V Sbjct: 24 AAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNP---KTV 80 Query: 134 DKTIINADKDGDGRISFEEFCAVVGGLDIHKKM 166 + D+ DG ISF+EF A L + Sbjct: 81 ELLSGVVDQTKDGLISFQEFVAFESVLCAPDAL 113 >3KPX-A nrPDB Length = 198 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 34/172 (19%), Positives = 63/172 (36%), Gaps = 30/172 (17%) Query: 6 SYPLEMCSHF-DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLV--------- 55 Y +++ ++F D + R F LD++ +G ++++E +S + Sbjct: 7 KYAVKLKTNFEDPKWVNRHKFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQR 66 Query: 56 -QRVIDIFDT----DGNGEVDFKEFIEG----------VSQFSVKGDKEQKLRFAFRIYD 100 Q ++ F D EV+F F+ G + + K F I+D Sbjct: 67 HQEAVEAFFKKIGLDYGKEVEFPAFVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFD 126 Query: 101 MDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 D G IS E + G D ++ T + D D G++ +E Sbjct: 127 KDGSGSISLDEWKT-YGGISGICPSDEDAEK----TFKHCDLDNSGKLDVDE 173 Score = 38.0 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113 + V DIFD DG+G + E+ S ++ F+ D+D G + E+ Sbjct: 117 WGEAVFDIFDKDGSGSISLDEWKTY-GGISGICPSDEDAEKTFKHCDLDNSGKLDVDEMT 175 Query: 114 Q 114 + Sbjct: 176 R 176 Score = 29.9 bits (66), Expect = 0.51, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 43/113 (38%), Gaps = 15/113 (13%) Query: 56 QRVIDIFDTDGNGEVDFKEFI--------EGVSQFSVKGDKEQKLRFAF-RIYDMDKDGY 106 + + + D +GNG++ E + + + + Q+ AF + +D Sbjct: 26 KFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYGKE 85 Query: 107 ISNGELFQVLKMMVGNNLK------DTQLQQIVDKTIINADKDGDGRISFEEF 153 + K + ++LK + ++ + DKDG G IS +E+ Sbjct: 86 VEFPAFVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEW 138 >2KYF-A nrPDB Length = 108 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 2/75 (2%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 + +L+ FRI D D+ G+I EL L+ T + + AD D Sbjct: 35 MSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASE--TKTFLAAADHD 92 Query: 144 GDGRISFEEFCAVVG 158 GDG+I EEF +V Sbjct: 93 GDGKIGAEEFQEMVQ 107 Score = 34.5 bits (78), Expect = 0.021, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 29/74 (39%), Gaps = 7/74 (9%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLP-------ELQQNPLVQRVIDIFDTD 65 S +L + F+ LD D SG + +E + + + D D Sbjct: 33 SGMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFLAAADHD 92 Query: 66 GNGEVDFKEFIEGV 79 G+G++ +EF E V Sbjct: 93 GDGKIGAEEFQEMV 106 >2KQY-A nrPDB Length = 108 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 5/90 (5%) Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 ++K F V + +++ F I D DK G+I EL LK + T Sbjct: 24 FNYKSFFSTVG---LSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSA 80 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + + D DGDG+I EEF ++V Sbjct: 81 E--TKAFLAAGDTDGDGKIGVEEFQSLVKA 108 Score = 34.9 bits (79), Expect = 0.017, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 29/74 (39%), Gaps = 7/74 (9%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLP-------ELQQNPLVQRVIDIFDTDGN 67 + ++ K F LD D SG + EE + + + + DTDG+ Sbjct: 35 LSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAFLAAGDTDGD 94 Query: 68 GEVDFKEFIEGVSQ 81 G++ +EF V Sbjct: 95 GKIGVEEFQSLVKA 108 >3TZ1-A nrPDB Length = 74 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 5/70 (7%) Query: 88 KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR 147 E++L+ AFR+ D +K G I L +LK L D + ++ I D DG G Sbjct: 5 DERELKEAFRVLDKEKKGVIKVDVLRWILKS-----LGDELTEDEIENMIAETDTDGSGT 59 Query: 148 ISFEEFCAVV 157 + +EEF ++ Sbjct: 60 VDYEEFKCLM 69 Score = 34.5 bits (78), Expect = 0.022, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 4/62 (6%) Query: 22 RLGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 L + F+ LD + G + V+ SL + ++ +I DTDG+G VD++EF Sbjct: 8 ELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEFKC 67 Query: 78 GV 79 + Sbjct: 68 LM 69 >1IJ5-A nrPDB Length = 323 Score = 47.6 bits (112), Expect = 2e-06, Method: Composition-based stats. Identities = 32/144 (22%), Positives = 65/144 (45%), Gaps = 14/144 (9%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMS---LPELQQNPLVQRVIDIFDTDGNGEVDFK 73 A+++ L F+K+D +++G+LS +EF + + + D D + +V F Sbjct: 184 ANDLAALVADFRKIDTNSNGTLSRKEFREHFVRLGFDKKSVQDALFRYADEDESDDVGFS 243 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 E++ V LR + D DK G +S E+ +VL+ ++ ++ ++ Sbjct: 244 EYVHLGLCLLV-------LRILYAFADFDKSGQLSKEEVQKVLEDA---HIPESARKKF- 292 Query: 134 DKTIINADKDGDGRISFEEFCAVV 157 + D D +S++EF +V Sbjct: 293 EHQFSVVDVDDSKSLSYQEFVMLV 316 Score = 40.3 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 20/146 (13%), Positives = 51/146 (34%), Gaps = 17/146 (11%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEV 70 ++ L + F + SG S ++ + + + ++++ + + D G + Sbjct: 116 LSEEDTNILRQLFLSSAVSGSGKFSFQDLKQVLAKYADTIPEGPLKKLFVMVENDTKGRM 175 Query: 71 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ 130 + + + + L FR D + +G +S E + + + Sbjct: 176 SYITLVAVANDLAA-------LVADFRKIDTNSNGTLSRKEFREHFVRL------GFDKK 222 Query: 131 QIVDKTIINADKDGDGRISFEEFCAV 156 + D AD+D + F E+ + Sbjct: 223 SVQDALFRYADEDESDDVGFSEYVHL 248 Score = 36.1 bits (82), Expect = 0.007, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 48/136 (35%), Gaps = 15/136 (11%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQF 82 L K F ++ D G +S +++ + DT+ NG + KEF E + Sbjct: 160 LKKLFVMVENDTKGRMSYITLVAVANDLAALVAD--FRKIDTNSNGTLSRKEFREHFVRL 217 Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADK 142 Q FR D D+ + E + ++ ++ AD Sbjct: 218 GFDKKSVQD--ALFRYADEDESDDVGFSEYVHLGLCLL-----------VLRILYAFADF 264 Query: 143 DGDGRISFEEFCAVVG 158 D G++S EE V+ Sbjct: 265 DKSGQLSKEEVQKVLE 280 Score = 33.0 bits (74), Expect = 0.059, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 58/153 (37%), Gaps = 12/153 (7%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 76 A E +RL K L+ D SG + + + +++++ G+G+ F++ Sbjct: 86 AAEKQRLASLLKDLEDDASGYNRLRPSKPMLSEEDTNILRQLFLSSAVSGSGKFSFQDLK 145 Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKT 136 + ++++ E L+ F + + D G +S L V + Sbjct: 146 QVLAKY-ADTIPEGPLKKLFVMVENDTKGRMSYITLVAVANDLAALVAD----------- 193 Query: 137 IINADKDGDGRISFEEFCAVVGGLDIHKKMVVD 169 D + +G +S +EF L KK V D Sbjct: 194 FRKIDTNSNGTLSRKEFREHFVRLGFDKKSVQD 226 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 41/95 (43%), Gaps = 4/95 (4%) Query: 26 RFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF-DTDGNGEVDFKEFIEGVSQFSV 84 F+ D D S + E++ L LV R++ F D D +G++ +E + + + Sbjct: 228 LFRYADEDESDDVGFSEYVHL---GLCLLVLRILYAFADFDKSGQLSKEEVQKVLEDAHI 284 Query: 85 KGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM 119 +K F + D+D +S E ++ +M Sbjct: 285 PESARKKFEHQFSVVDVDDSKSLSYQEFVMLVLLM 319 >2K7B-A nrPDB Length = 76 Score = 47.6 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 33/74 (44%), Gaps = 4/74 (5%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVID---IFDTDGNGE 69 +EI+ L + F++ D D G ++ + + + + P +I+ + + G Sbjct: 3 SLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGH 62 Query: 70 VDFKEFIEGVSQFS 83 VDF +F+E + Sbjct: 63 VDFDDFVELMGPKL 76 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 44/78 (56%), Gaps = 5/78 (6%) Query: 81 QFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA 140 S++ ++ ++LR AFR +D DKDGYI+ +L ++ M G + +L ++ + + Sbjct: 1 DRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTM-GYMPTEMELIELSQQINM-- 57 Query: 141 DKDGDGRISFEEFCAVVG 158 + G + F++F ++G Sbjct: 58 --NLGGHVDFDDFVELMG 73 >5E1J-A nrPDB Length = 741 Score = 47.6 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 39/95 (41%), Gaps = 2/95 (2%) Query: 70 VDFKEFIEGVSQFSVKGDKEQK--LRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127 V + F E +++ D+ ++ L AF + D DK+G I + ++ + + Sbjct: 303 VVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPK 362 Query: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 ++ D D +I+ +EF + + + Sbjct: 363 ISKEEFGLIFDELDDTRDFKINKDEFADLCQAIAL 397 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Query: 54 LVQRVIDIFDTDGNGEVDFKE----FIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISN 109 ++++ + D+D NGE+D + F + + ++ +++ F D +D I+ Sbjct: 326 MLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINK 385 Query: 110 GELFQVLKMMVGNNLKDTQL 129 E + + + K+ Sbjct: 386 DEFADLCQAIALRFQKEEVP 405 Score = 35.7 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 38/84 (45%), Gaps = 11/84 (13%) Query: 18 DEIKR--LGKRFKKLDLDNSGSLSVEEFMSLPELQQN----PLVQR-----VIDIFDTDG 66 D++KR L K F +D D +G + + + L E N P + + + D D Sbjct: 320 DQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTR 379 Query: 67 NGEVDFKEFIEGVSQFSVKGDKEQ 90 + +++ EF + +++ KE+ Sbjct: 380 DFKINKDEFADLCQAIALRFQKEE 403 Score = 28.0 bits (61), Expect = 2.1, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 18/41 (43%) Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKM 166 D +++++K D D +G I + + L ++ + Sbjct: 320 DQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTL 360 >3CS1-A nrPDB Length = 219 Score = 47.2 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 35/161 (21%), Positives = 58/161 (36%), Gaps = 19/161 (11%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF--MSLPELQQNPLVQRV----IDIFDT----- 64 A+ +R + FKK D + +G L +E L L+ + RV FD Sbjct: 43 TAEAKQRRIELFKKFDKNETGKLCYDEVYSGCLEVLKLDEFTSRVRDITKRAFDKSRTLG 102 Query: 65 ---DGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVG 121 + G DF EF+E D + L F D + + E + + + Sbjct: 103 SKLENKGSEDFVEFLEFRLMLCYIYDFFE-LTVMFDEIDASGNMLVDEEEFKRAVPKLEA 161 Query: 122 NNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 K + DK+G G ++F+EF A + + Sbjct: 162 WGAKVEDPAAL----FKELDKNGTGSVTFDEFAAWASAVKL 198 Score = 32.2 bits (72), Expect = 0.10, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 28/71 (39%), Gaps = 5/71 (7%) Query: 22 RLGKRFKKLDLDNSGSLSVEEFM-SLPELQQ----NPLVQRVIDIFDTDGNGEVDFKEFI 76 L F ++D + + EEF ++P+L+ + D +G G V F EF Sbjct: 131 ELTVMFDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAALFKELDKNGTGSVTFDEFA 190 Query: 77 EGVSQFSVKGD 87 S + D Sbjct: 191 AWASAVKLDAD 201 Score = 26.1 bits (56), Expect = 9.0, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 46/143 (32%), Gaps = 44/143 (30%) Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDK---EQKLRFAFRIYDMDKDGYISNGEL----FQV 115 D DG D KE E + Q + +Q+ F+ +D ++ G + E+ +V Sbjct: 18 DKDGKKAKDRKEAWERIRQAIPREKTAEAKQRRIELFKKFDKNETGKLCYDEVYSGCLEV 77 Query: 116 LK-------------------MMVGNNLKDTQLQQIVD------------------KTII 138 LK +G+ L++ + V+ Sbjct: 78 LKLDEFTSRVRDITKRAFDKSRTLGSKLENKGSEDFVEFLEFRLMLCYIYDFFELTVMFD 137 Query: 139 NADKDGDGRISFEEFCAVVGGLD 161 D G+ + EEF V L+ Sbjct: 138 EIDASGNMLVDEEEFKRAVPKLE 160 >1QXP-A nrPDB Length = 900 Score = 46.9 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 35/167 (20%), Positives = 60/167 (35%), Gaps = 27/167 (16%) Query: 9 LEMCSHFDADEIK-RLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ----------- 56 L +EI F KL + +SV+E ++ + Sbjct: 521 LPDEKVLSEEEIDDNFKTLFSKL-AGDDMEISVKELQTILNRIISKHKDLRTNGFSLESC 579 Query: 57 -RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 ++++ D DGNG++ EF ++ FR +D+DK G +S E+ + Sbjct: 580 RSMVNLMDRDGNGKLGLVEFNILWNRIRNYLTI-------FRKFDLDKSGSMSAYEMR-M 631 Query: 116 LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 G L Q IV + D + I F+ F + L+I Sbjct: 632 AIEAAGFKLPCQLHQVIVARF-----ADDELIIDFDNFVRCLVRLEI 673 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 36/91 (39%), Gaps = 10/91 (10%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF---DTDGNGEVDFKEFI 76 IK+ +K+ + D SG++ E E L Q + + +D G +DF FI Sbjct: 803 IKKWQGIYKRFETDRSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFI 862 Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYI 107 + + + AFR D + G I Sbjct: 863 SCLVRLDA-------MFRAFRSLDKNGTGQI 886 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 66/157 (42%), Gaps = 26/157 (16%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSL--------PELQQN----PLVQRVIDIFDT 64 ++E ++ K F +L + +S E M++ P+L+ + + ++ + D+ Sbjct: 727 SEEERQFRKLFVQL-AGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDS 785 Query: 65 DGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNL 124 D G++ F+EF + +K + ++ ++ D+ G I + EL + Sbjct: 786 DTTGKLGFEEF-------KYLWNNIKKWQGIYKRFETDRSGTIGSNELPGAFEAA----- 833 Query: 125 KDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 L Q + II D G + F+ F + + LD Sbjct: 834 -GFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLD 869 Score = 32.6 bits (73), Expect = 0.097, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 63/157 (40%), Gaps = 18/157 (11%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGV 79 ++ L K FK+LD +N+G++ + L ++ ++ + + + + Sbjct: 671 LEILFKIFKQLDPENTGTIQ----LDLISWLSFSVLGKLAAAIEHHHHHHMHYSN----- 721 Query: 80 SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNL---KDTQLQQIVDKT 136 + + ++E++ R F D D +S EL +L +V + D Sbjct: 722 -IEANESEEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSM 779 Query: 137 IINADKDGDGRISFEEFCAVVGGLD----IHKKMVVD 169 + D D G++ FEEF + + I+K+ D Sbjct: 780 VAVMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFETD 816 >2I18-A nrPDB Length = 64 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 36/70 (51%), Gaps = 9/70 (12%) Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 D + L+ +++ D+D DG ++ E V + K ++++ ++ + AD +GD Sbjct: 1 SDDKIGLKVLYKLMDVDGDGKLTKEE--------VTSFFKKHGIEKVAEQV-MKADANGD 51 Query: 146 GRISFEEFCA 155 G I+ EEF Sbjct: 52 GYITLEEFLE 61 Score = 34.9 bits (79), Expect = 0.019, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 27/55 (49%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 L +K +D+D G L+ EE S + V + D +G+G + +EF+E Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKADANGDGYITLEEFLE 61 >4PAL-A nrPDB Length = 108 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 5/90 (5%) Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 KEF V S D ++ AF + D DK G+I EL L+ + T Sbjct: 24 FKHKEFFAKVGLASKSLDD---VKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDA 80 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + + + DKDGDG I +EF A++ Sbjct: 81 E--TKAFLADGDKDGDGMIGVDEFAAMIKA 108 Score = 28.8 bits (63), Expect = 1.1, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 28/75 (37%), Gaps = 9/75 (12%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDI--------FDTDG 66 + + + K F +D D SG + +E L +P + + D D DG Sbjct: 35 LASKSLDDVKKAFYVIDQDKSGFIEEDELK-LFLQNFSPSARALTDAETKAFLADGDKDG 93 Query: 67 NGEVDFKEFIEGVSQ 81 +G + EF + Sbjct: 94 DGMIGVDEFAAMIKA 108 >1S36-A nrPDB Length = 195 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 58/157 (36%), Gaps = 29/157 (18%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRV--------------IDIFDTD 65 IKR F LD++ +G ++++E +S ++ + Sbjct: 19 IKRHKHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCGME 78 Query: 66 GNGEVDFKEFIEGVSQFSVKGDKE----------QKLRFAFRIYDMDKDGYISNGELFQV 115 E+ F +F++G Q + K+ + F I+D D G I+ E ++ Sbjct: 79 YGKEIAFPQFLDGFKQLATSELKKWARNEPTLIREWGDAVFDIFDKDGSGTITLDE-WKA 137 Query: 116 LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 + G + Q+ + T + D D G + +E Sbjct: 138 YGKISGISPS----QEDCEATFRHCDLDNSGDLDVDE 170 Score = 40.3 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 5/92 (5%) Query: 26 RFKKLDLDNSGSLSVEEFMSLPELQQN---PLVQRVIDIFDTDGNGEVDFKEFIEGVSQF 82 F + LD L+ E + V DIFD DG+G + E+ + + Sbjct: 84 AFPQF-LDGFKQLATSELKKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEW-KAYGKI 141 Query: 83 SVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 S ++ FR D+D G + E+ + Sbjct: 142 SGISPSQEDCEATFRHCDLDNSGDLDVDEMTR 173 >1KFX-S nrPDB Length = 184 Score = 46.1 bits (108), Expect = 7e-06, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 10/91 (10%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF---DTDGNGEVDFKEFI 76 IKR +K+ D D SG++ E E L + + ++ +D +G +DF FI Sbjct: 87 IKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFI 146 Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYI 107 + + + AF+ D D G I Sbjct: 147 SCLVRLDA-------MFRAFKSLDKDGTGQI 170 Score = 41.1 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 69/157 (43%), Gaps = 26/157 (16%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSL--------PELQQN----PLVQRVIDIFDT 64 ++E+++ + F +L + +S E M++ P+L+ + + ++ + D+ Sbjct: 11 SEEVRQFRRLFAQL-AGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDS 69 Query: 65 DGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNL 124 D G++ F+EF + ++ + ++ +D D+ G I + EL + G +L Sbjct: 70 DTTGKLGFEEF-------KYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAA-GFHL 121 Query: 125 KDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 + I+ + D G + F+ F + + LD Sbjct: 122 NEHLYNMIIRRY-----SDESGNMDFDNFISCLVRLD 153 >1ZFS-A nrPDB Length = 93 Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 30/57 (52%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S EL +L+ + + L + VDK + D++GDG + F+EF +V L + Sbjct: 27 KLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAALTV 83 Score = 29.9 bits (66), Expect = 0.63, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 29/57 (50%), Gaps = 9/57 (15%) Query: 37 SLSVEEFMSLPELQQNPLVQ---------RVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 LS +E L + + + + +++ D +G+GEVDF+EF+ V+ +V Sbjct: 27 KLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAALTV 83 >2M1U-A nrPDB Length = 93 Score = 45.3 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 40/81 (49%), Gaps = 6/81 (7%) Query: 81 QFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA 140 + S D++ +L AF +D D DG++S E +++ G + + + + + A Sbjct: 17 RGSHMSDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRD--GLPMTEAE----ITEFFEAA 70 Query: 141 DKDGDGRISFEEFCAVVGGLD 161 D + G I ++ F A++ +D Sbjct: 71 DPNNTGFIDYKAFAAMLYSVD 91 Score = 43.0 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 28/67 (41%), Gaps = 3/67 (4%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRV---IDIFDTDGNGEVDFK 73 +DE +L + F D D G +SVEEF + + + D + G +D+K Sbjct: 22 SDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRDGLPMTEAEITEFFEAADPNNTGFIDYK 81 Query: 74 EFIEGVS 80 F + Sbjct: 82 AFAAMLY 88 >4OKH-A nrPDB Length = 189 Score = 45.3 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 10/98 (10%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFD---TDGNGEVDFKE 74 ++IK K FK D D SG+++ E + L ++ DI D + +DF Sbjct: 82 NKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDS 141 Query: 75 FIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 FI + + + AF +D D DG I L Sbjct: 142 FICCFVRL-------EGMFRAFHAFDKDGDGIIKLNVL 172 Score = 40.3 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 26/155 (16%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ------------RVI 59 S +++E ++ FK++ + + +E + N +I Sbjct: 3 SSDQESEEQQQFRNIFKQI-AGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMI 61 Query: 60 DIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM 119 + DTDG+G+++ +EF K QK+ F+ YD D+ G I++ E+ + Sbjct: 62 ALMDTDGSGKLNLQEF----HHLWNKIKAWQKI---FKHYDTDQSGTINSYEMRNAVNDA 114 Query: 120 VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 G +L + I T+ ADK I F+ F Sbjct: 115 -GFHLNNQLYDII---TMRYADKH--MNIDFDSFI 143 Score = 34.2 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 38/91 (41%), Gaps = 4/91 (4%) Query: 79 VSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNL---KDTQLQQIVDK 135 + + +++Q+ R F+ D D I EL +VL +V + + Sbjct: 1 MGSSDQESEEQQQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLKTHGFTLESCRS 59 Query: 136 TIINADKDGDGRISFEEFCAVVGGLDIHKKM 166 I D DG G+++ +EF + + +K+ Sbjct: 60 MIALMDTDGSGKLNLQEFHHLWNKIKAWQKI 90 >2LUC-A nrPDB Length = 105 Score = 44.6 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Query: 79 VSQFSVKGDKEQKLRFAFRIYDM--DKDGY---ISNGELFQVLKMMVGNNLKDTQLQQIV 133 +++ S + E+ + ++ KDGY +S E + + K+ + ++ Sbjct: 1 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL 60 Query: 134 DKTIINADKDGDGRISFEEFCAVVGGLDI 162 D+ + D + DG++ F EF ++GGL + Sbjct: 61 DRMMKKLDTNSDGQLDFSEFLNLIGGLAM 89 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 32/77 (41%), Gaps = 13/77 (16%) Query: 16 DADEIKRLGKRFKKLDLDNSG---SLSVEEFMSLPELQQNPL---------VQRVIDIFD 63 I+ L F+K G +LS EF+S + + R++ D Sbjct: 10 TERCIESLIAVFQKY-AGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLD 68 Query: 64 TDGNGEVDFKEFIEGVS 80 T+ +G++DF EF+ + Sbjct: 69 TNSDGQLDFSEFLNLIG 85 >1A75-A nrPDB Length = 108 Score = 44.6 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 6/78 (7%) Query: 84 VKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV--GNNLKDTQLQQIVDKTIINAD 141 + G ++ AF D DK G+I EL L++ L D + + + D Sbjct: 35 LSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETK----AFLKAGD 90 Query: 142 KDGDGRISFEEFCAVVGG 159 DGDG I EE+ A+V Sbjct: 91 SDGDGAIGVEEWVALVKA 108 Score = 30.7 bits (68), Expect = 0.29, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 28/74 (37%), Gaps = 7/74 (9%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEE-------FMSLPELQQNPLVQRVIDIFDTDGN 67 + K F +D D SG + +E F + + + + D+DG+ Sbjct: 35 LSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAFLKAGDSDGD 94 Query: 68 GEVDFKEFIEGVSQ 81 G + +E++ V Sbjct: 95 GAIGVEEWVALVKA 108 >1G33-A nrPDB Length = 73 Score = 44.6 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 2/73 (2%) Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 ++ F I D DK G+I EL +LK + + + DKDGD Sbjct: 1 MKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDAR--DLSAKETKTLMAAGDKDGD 58 Query: 146 GRISFEEFCAVVG 158 G+I EEF +V Sbjct: 59 GKIGVEEFSTLVA 71 Score = 32.6 bits (73), Expect = 0.097, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 7/65 (10%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQR-------VIDIFDTDGNGEVDFKEFI 76 K F LD D SG + +E S+ + + ++ D DG+G++ +EF Sbjct: 8 KKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFS 67 Query: 77 EGVSQ 81 V++ Sbjct: 68 TLVAE 72 Score = 29.1 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 49 LQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGD--KEQKLRFAFRIYDMDKDGY 106 ++ V++V I D D +G ++ E + FS ++ + D D DG Sbjct: 1 MKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGK 60 Query: 107 ISNGELFQVLKM 118 I E ++ Sbjct: 61 IGVEEFSTLVAE 72 >1BU3-A nrPDB Length = 109 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 5/90 (5%) Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 ++K F V + D ++ AF + D DK G+I EL L++ T Sbjct: 25 FNYKAFFAKVGLTAKSADD---IKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDA 81 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + + D DGDG I +E+ A+V Sbjct: 82 E--TKAFLKAGDSDGDGAIGVDEWAALVKA 109 Score = 30.7 bits (68), Expect = 0.29, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 27/74 (36%), Gaps = 7/74 (9%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEE---FMSLPELQQNPLVQRVIDIF----DTDGN 67 A + K F +D D SG + +E F+ + L F D+DG+ Sbjct: 36 LTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAFLKAGDSDGD 95 Query: 68 GEVDFKEFIEGVSQ 81 G + E+ V Sbjct: 96 GAIGVDEWAALVKA 109 >5XOP-A nrPDB Length = 66 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 4/58 (6%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSL----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 FK++D++ G++S EE + ++ L+Q + D DG+G +DF+EF + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAK 60 Score = 42.6 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 5/68 (7%) Query: 93 RFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 F+ D++ DG +S E+ + +Q++ + DKDGDG I FEE Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIK-----NEQLLQLIFKSIDKDGDGFIDFEE 57 Query: 153 FCAVVGGL 160 F G + Sbjct: 58 FAKFYGSI 65 Score = 41.1 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113 + + + D +G+G V ++E ++ EQ L+ F+ D D DG+I E Sbjct: 1 MAEALFKEIDVNGDGAVSYEE-VKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFA 59 Query: 114 Q 114 + Sbjct: 60 K 60 Score = 27.6 bits (60), Expect = 2.5, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 14/28 (50%) Query: 132 IVDKTIINADKDGDGRISFEEFCAVVGG 159 + + D +GDG +S+EE A V Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSK 28 Score = 27.6 bits (60), Expect = 2.6, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 12/26 (46%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSL 46 + L FK +D D G + EEF Sbjct: 36 QLLQLIFKSIDKDGDGFIDFEEFAKF 61 >5VE9-A nrPDB Length = 91 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 4/57 (7%) Query: 27 FKKLDLDNSGSLSVEEFMSLPELQQNPLVQ----RVIDIFDTDGNGEVDFKEFIEGV 79 F+++D D G ++ +EF+ + P + V DIFD DG+G +D+ EF+ + Sbjct: 33 FRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAAL 89 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 5/63 (7%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 FR D D+DG I+ E + ++ + T+L+ + D+DGDG I + EF A Sbjct: 33 FRRIDKDQDGKITRQEF---IDGILASKFPTTKLE--MTAVADIFDRDGDGYIDYYEFVA 87 Query: 156 VVG 158 + Sbjct: 88 ALH 90 >2WCE-A nrPDB Length = 95 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 31/53 (58%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 +S GEL Q+L + N +K+ + + ++D+ D + D ++ F+EF ++V Sbjct: 30 TLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMVA 82 Score = 29.1 bits (64), Expect = 0.95, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 25/55 (45%), Gaps = 1/55 (1%) Query: 27 FKKLDLDNSGSLSVEEFM-SLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVS 80 F L L +E ++ ++ ++ + D + + +VDF+EFI V+ Sbjct: 28 FDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMVA 82 >5HYD-A nrPDB Length = 99 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 29/57 (50%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S GEL +L+ + L + Q+VDK + + D + D + F EF +V L + Sbjct: 28 KLSKGELKLLLQRELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVAALTV 84 Score = 27.6 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Query: 41 EEFMSLPE-LQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 E ++ LV +++ D + + EVDF EF+ V+ +V Sbjct: 40 RELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVAALTV 84 >2M7M-A nrPDB Length = 66 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 4/58 (6%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSL----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 FK++D++ G++S EE + ++ L+Q + D DGNGE+D EF + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAK 60 Score = 39.5 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 27/68 (39%), Gaps = 5/68 (7%) Query: 93 RFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 F+ D++ DG +S E+ + +Q++ + D DG+G I E Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIK-----NEQLLQLIFKSIDADGNGEIDQNE 57 Query: 153 FCAVVGGL 160 F G + Sbjct: 58 FAKFYGSI 65 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113 + + + D +G+G V ++E ++ EQ L+ F+ D D +G I E Sbjct: 1 MAEALFKEIDVNGDGAVSYEE-VKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFA 59 Query: 114 Q 114 + Sbjct: 60 K 60 Score = 28.4 bits (62), Expect = 1.5, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 14/28 (50%) Query: 132 IVDKTIINADKDGDGRISFEEFCAVVGG 159 + + D +GDG +S+EE A V Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSK 28 >1NSH-A nrPDB Length = 101 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Query: 90 QKLRFAFRIYDMDKDG---YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 + L F+ Y KDG +S E + + K+ + ++D+ + D + DG Sbjct: 11 ESLIAVFQKY-AGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDG 69 Query: 147 RISFEEFCAVVGGLDI 162 ++ F+EF ++GGL + Sbjct: 70 QLDFQEFLNLIGGLAV 85 Score = 31.1 bits (69), Expect = 0.25, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 32/77 (41%), Gaps = 13/77 (16%) Query: 16 DADEIKRLGKRFKKLDLDNSG---SLSVEEFMSLPELQQNPL---------VQRVIDIFD 63 I+ L F+K G +LS EF+S + + R++ D Sbjct: 6 TERCIESLIAVFQKY-AGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLD 64 Query: 64 TDGNGEVDFKEFIEGVS 80 + +G++DF+EF+ + Sbjct: 65 LNSDGQLDFQEFLNLIG 81 >2L0P-A nrPDB Length = 94 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 30/57 (52%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S EL ++L+ + L + VDK + D++GDG + F+E+ +V L + Sbjct: 28 KLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAALTV 84 Score = 27.2 bits (59), Expect = 3.2, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 29/57 (50%), Gaps = 9/57 (15%) Query: 37 SLSVEEFMSLPELQQNPLVQ---------RVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 LS +E L + + + + +V+ D +G+GEVDF+E++ V+ +V Sbjct: 28 KLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAALTV 84 >1Q80-A nrPDB Length = 174 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 32/154 (20%), Positives = 59/154 (38%), Gaps = 26/154 (16%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNP----------LVQRVIDIFD-----T 64 ++++ F ++D D G+++ +F S+ E L+ + ++D Sbjct: 5 VQKMKTYFNRIDFDKDGAITRMDFESMAERFAKESEMKAEHAKVLMDSLTGVWDNFLTAV 64 Query: 65 DGNGEVDFKEFIEGVSQFSV----KGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV 120 G +D FI + + K E L FR D ++D IS E + M+ Sbjct: 65 AGGKGIDETTFINSMKEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDEYG-IFFGML 123 Query: 121 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 G + + + D + DG +S EEF Sbjct: 124 GLDKT------MAPASFDAIDTNNDGLLSLEEFV 151 Score = 29.9 bits (66), Expect = 0.64, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 41/120 (34%), Gaps = 14/120 (11%) Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYD------------MDKDGY 106 + D D +G + +F +F+ + E K A + D + Sbjct: 12 FNRIDFDKDGAITRMDFESMAERFAKE--SEMKAEHAKVLMDSLTGVWDNFLTAVAGGKG 69 Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKM 166 I +K MV N + ++ + D + D IS +E+ G L + K M Sbjct: 70 IDETTFINSMKEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDEYGIFFGMLGLDKTM 129 >1TTX-A nrPDB Length = 109 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 +++ FR D D+ GY+ EL L+ + + + AD DGDG+I Sbjct: 43 QVKDVFRFIDNDQSGYLDEEELKFFLQKF--ESGARELTESETKSLMAAADNDGDGKIGA 100 Query: 151 EEFCAVVG 158 EEF +V Sbjct: 101 EEFQEMVH 108 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 32/82 (39%), Gaps = 9/82 (10%) Query: 6 SYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL--------PELQQNPLVQR 57 S ++ F+ +D D SG L EE EL ++ + Sbjct: 27 PQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESET-KS 85 Query: 58 VIDIFDTDGNGEVDFKEFIEGV 79 ++ D DG+G++ +EF E V Sbjct: 86 LMAAADNDGDGKIGAEEFQEMV 107 Score = 31.8 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 26/64 (40%), Gaps = 2/64 (3%) Query: 55 VQRVIDIFDTDGNGEVDFKE--FIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 V+ V D D +G +D +E F + + E + + D D DG I E Sbjct: 44 VKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEF 103 Query: 113 FQVL 116 +++ Sbjct: 104 QEMV 107 >3BOW-B nrPDB Length = 184 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 10/91 (10%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF---DTDGNGEVDFKEFI 76 IK+ +K+ D D SG++ E E L Q + + +D G +DF FI Sbjct: 87 IKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFI 146 Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYI 107 + + + AFR D + G I Sbjct: 147 SCLVRLDA-------MFRAFRSLDKNGTGQI 170 Score = 38.4 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 32/157 (20%), Positives = 66/157 (42%), Gaps = 26/157 (16%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSL--------PELQQN----PLVQRVIDIFDT 64 ++E ++ K F +L + +S E M++ P+L+ + + ++ + D+ Sbjct: 11 SEEERQFRKLFVQL-AGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDS 69 Query: 65 DGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNL 124 D G++ F+EF + +K + ++ +D D+ G I + EL + Sbjct: 70 DTTGKLGFEEF-------KYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAA----- 117 Query: 125 KDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 L Q + II D G + F+ F + + LD Sbjct: 118 -GFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLD 153 >4L9M-A nrPDB Length = 559 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 10/59 (16%) Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 +V V +D D +G + +EF + + F F+F + D D++G IS E+ Sbjct: 426 MVDSVFKNYDHDQDGYISQEEFEKIAASFP----------FSFCVMDKDREGLISRDEI 474 Score = 37.6 bits (86), Expect = 0.002, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 15/72 (20%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 F+ YD D+DGYIS E ++ + DKD +G IS +E A Sbjct: 431 FKNYDHDQDGYISQEEFEKIAASFPFS--------------FCVMDKDREGLISRDEITA 476 Query: 156 -VVGGLDIHKKM 166 + I+ K+ Sbjct: 477 YFMRASSIYSKL 488 Score = 35.3 bits (80), Expect = 0.012, Method: Composition-based stats. Identities = 13/28 (46%), Positives = 17/28 (60%) Query: 129 LQQIVDKTIINADKDGDGRISFEEFCAV 156 +Q++VD N D D DG IS EEF + Sbjct: 423 VQRMVDSVFKNYDHDQDGYISQEEFEKI 450 Score = 31.1 bits (69), Expect = 0.23, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 24/66 (36%), Gaps = 9/66 (13%) Query: 25 KRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE----FIEGVS 80 FK D D G +S EEF + P + D D G + E F+ S Sbjct: 429 SVFKNYDHDQDGYISQEEFEKIAA--SFPFS---FCVMDKDREGLISRDEITAYFMRASS 483 Query: 81 QFSVKG 86 +S G Sbjct: 484 IYSKLG 489 >5VT9-A nrPDB Length = 152 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 56/142 (39%), Gaps = 10/142 (7%) Query: 18 DEIKRLGKRFKKLDLDNSG-SLSVEEFMSL-PELQQNPLVQRVIDIFDTDGNGEVDFKEF 75 +E+ + + + + SG +S + M L +L P F+ +D+ F Sbjct: 14 EEMVEADEMYARFNARASGGKVSTGDAMILARQLGLAPSYAD-KQAFEEKSGDNLDYASF 72 Query: 76 IEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDK 135 + V + D + L AF +D+ K GY++ ++ +L M G L + + + Sbjct: 73 QKFVGTSTHPEDNIEDLVEAFAYFDVSKHGYLTRKQMGNIL-MTYGEPLTTEEFNALAAE 131 Query: 136 TIINADKDGDGRISFEEFCAVV 157 +I + +FC + Sbjct: 132 YFT------SDQIDYRQFCKAM 147 Score = 33.8 bits (76), Expect = 0.038, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 30/69 (43%), Gaps = 2/69 (2%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTD--GNGEV 70 S D I+ L + F D+ G L+ ++ ++ PL + + + ++ Sbjct: 79 STHPEDNIEDLVEAFAYFDVSKHGYLTRKQMGNILMTYGEPLTTEEFNALAAEYFTSDQI 138 Query: 71 DFKEFIEGV 79 D+++F + + Sbjct: 139 DYRQFCKAM 147 >1JUO-A nrPDB Length = 198 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 49/135 (36%), Gaps = 23/135 (17%) Query: 35 SGSLSVEEFM-----SLPELQQNPLVQR----VIDIFDTDGNGEVDFKEFIEGVSQFSVK 85 G + +E S P ++ + D D +G + F EF E + + Sbjct: 46 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLN-- 103 Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 R F +D D+ G + EL + L M G L + I + N Sbjct: 104 -----GWRQHFISFDTDRSGTVDPQELQKALTTM-GFRLSPQAVNSIAKRYSTN------ 151 Query: 146 GRISFEEFCAVVGGL 160 G+I+F+++ A L Sbjct: 152 GKITFDDYIACCVKL 166 Score = 37.6 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 34/92 (36%), Gaps = 9/92 (9%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPLVQRVIDIFDT-DGNGEVDFKEFIE 77 + + F D D SG++ +E +L + Q V I NG++ F ++I Sbjct: 102 LNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIA 161 Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISN 109 + D FR D + G ++ Sbjct: 162 CCVKLRALTDS-------FRRRDTAQQGVVNF 186 Score = 36.1 bits (82), Expect = 0.007, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 18/130 (13%) Query: 28 KKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGD 87 LD D SG++ EF L + + FDTD +G VD +E + ++ + Sbjct: 80 SMLDRDMSGTMGFNEFKELWAVLNGWRQHFI--SFDTDRSGTVDPQELQKALTTMGFRLS 137 Query: 88 KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR 147 + A R +G I+ + + L D+ D G Sbjct: 138 PQAVNSIAKRY---STNGKITFDDYIACCVKLRA--LTDS---------FRRRDTAQQGV 183 Query: 148 ISF--EEFCA 155 ++F ++F Sbjct: 184 VNFPYDDFIQ 193 Score = 30.7 bits (68), Expect = 0.37, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 19/54 (35%) Query: 103 KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAV 156 +DG I EL + L + + D+D G + F EF + Sbjct: 45 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKEL 98 >5CPV-A nrPDB Length = 109 Score = 43.0 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 5/90 (5%) Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 + K F V S D ++ AF I D DK G+I EL L+ + Sbjct: 25 FNHKAFFAKVGLTSKSADD---VKKAFAIIDQDKSGFIEEDELKLFLQNFKADAR--ALT 79 Query: 130 QQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + D DGDG+I +EF A+V Sbjct: 80 DGETKTFLKAGDSDGDGKIGVDEFTALVKA 109 Score = 28.4 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 26/74 (35%), Gaps = 7/74 (9%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLP-------ELQQNPLVQRVIDIFDTDGN 67 + + K F +D D SG + +E + + + D+DG+ Sbjct: 36 LTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFLKAGDSDGD 95 Query: 68 GEVDFKEFIEGVSQ 81 G++ EF V Sbjct: 96 GKIGVDEFTALVKA 109 >1QLS-A nrPDB Length = 99 Score = 42.6 bits (99), Expect = 8e-05, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 30/60 (50%) Query: 103 KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 + IS E + + ++ + ++D+ + D D DG++ F+EF ++GGL I Sbjct: 28 NNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFLNLIGGLAI 87 Score = 27.6 bits (60), Expect = 2.9, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 25/40 (62%), Gaps = 1/40 (2%) Query: 42 EFMSLPELQQNP-LVQRVIDIFDTDGNGEVDFKEFIEGVS 80 E + + Q++P ++ R++ D D +G++DF+EF+ + Sbjct: 44 ELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFLNLIG 83 >2NLN-A nrPDB Length = 108 Score = 42.6 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 21/70 (30%), Positives = 37/70 (52%), Gaps = 6/70 (8%) Query: 91 KLRFAFRIYDMDKDGYISNGELFQVLKMMVGN--NLKDTQLQQIVDKTIINADKDGDGRI 148 +++ FR D D+ GY+ EL L+ + L +++ + ++D AD DGDG+I Sbjct: 42 QVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMD----AADNDGDGKI 97 Query: 149 SFEEFCAVVG 158 +EF +V Sbjct: 98 GADEFQEMVH 107 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 26/64 (40%), Gaps = 2/64 (3%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDK--EQKLRFAFRIYDMDKDGYISNGEL 112 V+ + D D +G +D E + +F + E + + D D DG I E Sbjct: 43 VKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADEF 102 Query: 113 FQVL 116 +++ Sbjct: 103 QEMV 106 Score = 31.1 bits (69), Expect = 0.22, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 32/82 (39%), Gaps = 9/82 (10%) Query: 6 SYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM--------SLPELQQNPLVQR 57 S ++ F+ +D D SG L +E EL ++ + Sbjct: 26 PQKFFQTSGLSKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESET-KS 84 Query: 58 VIDIFDTDGNGEVDFKEFIEGV 79 ++D D DG+G++ EF E V Sbjct: 85 LMDAADNDGDGKIGADEFQEMV 106 >1TIZ-A nrPDB Length = 67 Score = 42.6 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 5/68 (7%) Query: 93 RFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 + F +D +KDG +S E +V Q+ + K D DG+G ++ +E Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYF-----TQEDIVKFFEEIDVDGNGELNADE 58 Query: 153 FCAVVGGL 160 F + + + Sbjct: 59 FTSCIEKM 66 Score = 36.8 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 1/66 (1%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114 +RV + FD + +G++ EF E FS +E ++F F D+D +G ++ E Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKF-FEEIDVDGNGELNADEFTS 61 Query: 115 VLKMMV 120 ++ M+ Sbjct: 62 CIEKML 67 Score = 34.9 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 6/57 (10%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSLPELQQNPL-----VQRVIDIFDTDGNGEVDFKEF 75 + F+K D + G LS++EF + L +P + + + D DGNGE++ EF Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREV-ALAFSPYFTQEDIVKFFEEIDVDGNGELNADEF 59 >1BOD-A nrPDB Length = 74 Score = 42.2 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 ++L+ F YD + DG +S EL +L+ + LK +D+ DK+GD Sbjct: 1 MKSPEELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMST---LDELFEELDKNGD 57 Query: 146 GRISFEEFCAVVGGLD 161 G +SFEEF +V + Sbjct: 58 GEVSFEEFQVLVKKIS 73 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPE------LQQNPLVQRVIDIFDTDGNGEVDFKE 74 + L F+K D + G LS EE L + L+ + + + D +G+GEV F+E Sbjct: 5 EELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEVSFEE 64 Query: 75 FIEGVSQFS 83 F V + S Sbjct: 65 FQVLVKKIS 73 >1NYA-A nrPDB Length = 176 Score = 42.2 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 52/123 (42%), Gaps = 23/123 (18%) Query: 17 ADEIKRLGKRFK-KLD-------LDNSGSLSVEEFMSLPELQQN------------PLVQ 56 A E++ L F D + + GSL+ E+F+ + E P+V+ Sbjct: 46 AAEVQTLKNAFGGLFDYLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVK 105 Query: 57 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL 116 ++ + D + +G+++ EF ++ G + + AF D + +G +S EL + Sbjct: 106 GIVGMCDKNADGQINADEFAAWLTAL---GMSKAEAAEAFNQVDTNGNGELSLDELLTAV 162 Query: 117 KMM 119 + Sbjct: 163 RDF 165 Score = 39.9 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 34/154 (22%), Positives = 61/154 (39%), Gaps = 37/154 (24%) Query: 22 RLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQ 81 RL KRF + D D +G+L +F Q + + F D Sbjct: 8 RLKKRFDRWDFDGNGALERADF--------EKEAQHIAEAFGKDAGAA------------ 47 Query: 82 FSVKGDKEQKLRFAF-RIYD-------MDKDGYISNGELFQVLKMMV---GNNLKDTQLQ 130 + Q L+ AF ++D + DG ++ + +V + ++ G + L Sbjct: 48 ------EVQTLKNAFGGLFDYLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLG 101 Query: 131 QIVDKTIINADKDGDGRISFEEFCAVVGGLDIHK 164 +V + DK+ DG+I+ +EF A + L + K Sbjct: 102 PVVKGIVGMCDKNADGQINADEFAAWLTALGMSK 135 Score = 34.9 bits (79), Expect = 0.017, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 25/57 (43%), Gaps = 2/57 (3%) Query: 29 KLDLDNSGSLSVEEFMS-LPELQQNPL-VQRVIDIFDTDGNGEVDFKEFIEGVSQFS 83 D + G ++ +EF + L L + + DT+GNGE+ E + V F Sbjct: 110 MCDKNADGQINADEFAAWLTALGMSKAEAAEAFNQVDTNGNGELSLDELLTAVRDFH 166 Score = 28.8 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 30/86 (34%), Gaps = 10/86 (11%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQ----------IVDKTIIN 139 +L+ F +D D +G + + + + + KD + + D Sbjct: 7 DRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAKE 66 Query: 140 ADKDGDGRISFEEFCAVVGGLDIHKK 165 A DG ++ E+F V L + Sbjct: 67 AGVGSDGSLTEEQFIRVTENLIFEQG 92 >3H4S-E nrPDB Length = 135 Score = 42.2 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 17/110 (15%), Positives = 42/110 (38%), Gaps = 4/110 (3%) Query: 52 NPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGE 111 P + ++ + E +++ + +++ + +L F + + I+ Sbjct: 2 EPTEKSMLLETTSTTKMETKYEDMLPVMAEKMDVEEFVSELCKGFSLLADPERHLITAES 61 Query: 112 LFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 L + ++ + Q +V D DGDG ++ EFC ++ L Sbjct: 62 LRRNSGILGIEGMSKEDAQGMV----REGDLDGDGALNQTEFCVLMVRLS 107 Score = 30.3 bits (67), Expect = 0.39, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 32/87 (36%), Gaps = 6/87 (6%) Query: 11 MCSHFDADE-IKRLGKRFKKLDLDNSGSLSVEEFMS-----LPELQQNPLVQRVIDIFDT 64 M D +E + L K F L ++ E E Q ++ D Sbjct: 29 MAEKMDVEEFVSELCKGFSLLADPERHLITAESLRRNSGILGIEGMSKEDAQGMVREGDL 88 Query: 65 DGNGEVDFKEFIEGVSQFSVKGDKEQK 91 DG+G ++ EF + + S + ++ + Sbjct: 89 DGDGALNQTEFCVLMVRLSPEMMEDAE 115 >2VRG-A nrPDB Length = 124 Score = 42.2 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 8/94 (8%) Query: 73 KEFIEGVSQFSVKGDKEQKLRF-AFRIYDMDKDGYISNGELFQVLKMMVGNN-------L 124 E +EGV Q+L+ F+++D D + + EL + + + Sbjct: 31 MEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLM 90 Query: 125 KDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 + +L I+D + + DK+ DG I + EF + Sbjct: 91 SEDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 124 >5MRA-A nrPDB Length = 167 Score = 42.2 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 49/135 (36%), Gaps = 23/135 (17%) Query: 35 SGSLSVEEFM-----SLPELQQNPLVQR----VIDIFDTDGNGEVDFKEFIEGVSQFSVK 85 G + +E S P ++ + D D +G + F EF E + + Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLN-- 72 Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 R F +D D+ G + EL + L M G L + I + N Sbjct: 73 -----GWRQHFISFDTDRSGTVDPQELQKALTTM-GFRLSPQAVNSIAKRYSTN------ 120 Query: 146 GRISFEEFCAVVGGL 160 G+I+F+++ A L Sbjct: 121 GKITFDDYIACCVKL 135 Score = 36.8 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 34/92 (36%), Gaps = 9/92 (9%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPLVQRVIDIFDT-DGNGEVDFKEFIE 77 + + F D D SG++ +E +L + Q V I NG++ F ++I Sbjct: 71 LNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIA 130 Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISN 109 + D FR D + G ++ Sbjct: 131 CCVKLRALTDS-------FRRRDTAQQGVVNF 155 Score = 34.9 bits (79), Expect = 0.016, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 18/130 (13%) Query: 28 KKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGD 87 LD D SG++ EF L + + FDTD +G VD +E + ++ + Sbjct: 49 SMLDRDMSGTMGFNEFKELWAVLNGWRQHFI--SFDTDRSGTVDPQELQKALTTMGFRLS 106 Query: 88 KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR 147 + A R +G I+ + + L D+ D G Sbjct: 107 PQAVNSIAKRY---STNGKITFDDYIACCVKLRA--LTDS---------FRRRDTAQQGV 152 Query: 148 ISF--EEFCA 155 ++F ++F Sbjct: 153 VNFPYDDFIQ 162 Score = 29.9 bits (66), Expect = 0.51, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 21/59 (35%) Query: 103 KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 +DG I EL + L + + D+D G + F EF + L+ Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLN 72 >4I5L-B nrPDB Length = 413 Score = 41.9 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 43/109 (39%), Gaps = 7/109 (6%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPLVQRVIDIFDTDG-- 66 ++ F + + +F +LD D+ + ++ ++ R+ T G Sbjct: 187 QLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAVTRGRK 246 Query: 67 ---NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 G++ + +F+ + K + + FR D+D DG +S EL Sbjct: 247 VQKEGKISYADFVWFLISEEDKKTP-TSIEYWFRCMDLDGDGALSMFEL 294 >3A4U-B nrPDB Length = 143 Score = 41.9 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 8/94 (8%) Query: 73 KEFIEGVSQFSVKGDKEQKLRF-AFRIYDMDKDGYISNGELFQVLKMMVGNN-------L 124 E +EGV Q+L+ F+++D D + + EL + + + Sbjct: 50 MEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLM 109 Query: 125 KDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 + +L I+D + + DK+ DG I + EF + Sbjct: 110 SEDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 143 >1CB1-A nrPDB Length = 78 Score = 41.9 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 87 DKEQKLRFAFRIYD-MDKD-GYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDG 144 +L+ F Y + D +S EL Q+++ + LK + +D DK+G Sbjct: 4 KSPAELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRT---LDDLFQELDKNG 60 Query: 145 DGRISFEEFCAVVGGLD 161 DG +SFEEF +V + Sbjct: 61 DGEVSFEEFQVLVKKIS 77 Score = 32.2 bits (72), Expect = 0.10, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 7/78 (8%) Query: 12 CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-----PELQQNP-LVQRVIDIFDTD 65 + E+K + +++ + D + LS EE L P L + P + + D + Sbjct: 1 SAQKSPAELKSIFEKYAAKEGDPN-QLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKN 59 Query: 66 GNGEVDFKEFIEGVSQFS 83 G+GEV F+EF V + S Sbjct: 60 GDGEVSFEEFQVLVKKIS 77 >2M7L-A nrPDB Length = 144 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/115 (15%), Positives = 42/115 (36%), Gaps = 12/115 (10%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPE----------LQQNPLVQRVID 60 S A++++ + F D ++ G L EF S ++ + + Sbjct: 2 SSSGVTAEQMQEFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQYDAIYN 61 Query: 61 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 NG V F +++ + + + + ++L F KD I+ ++ + Sbjct: 62 NVTKGENG-VSFDNYVQYMKEKNDENPSPEQLNEIFSTIAAGKD-SITETDMQKA 114 >2MBX-A nrPDB Length = 109 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 35/94 (37%), Gaps = 5/94 (5%) Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 G D K F V + ++ F I D DK ++ EL L+ Sbjct: 21 AEGSFDHKAFFTKVG---LAAKSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARA 77 Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + + + D DGDG+I +EF A++ Sbjct: 78 LSDAE--TKVFLKAGDSDGDGKIGVDEFGAMIKA 109 Score = 25.7 bits (55), Expect = 9.5, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 26/74 (35%), Gaps = 7/74 (9%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLP-------ELQQNPLVQRVIDIFDTDGN 67 A + K F+ +D D S + +E + + + D+DG+ Sbjct: 36 LAAKSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAETKVFLKAGDSDGD 95 Query: 68 GEVDFKEFIEGVSQ 81 G++ EF + Sbjct: 96 GKIGVDEFGAMIKA 109 >5I2L-A nrPDB Length = 120 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 4/73 (5%) Query: 8 PLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFD 63 P F +IK + K FK+ D G + + E + E P ++ +I D Sbjct: 18 PYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVD 77 Query: 64 TDGNGEVDFKEFI 76 D + ++ F+EF+ Sbjct: 78 EDFDSKLSFREFL 90 Score = 39.2 bits (90), Expect = 8e-04, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 30/70 (42%), Gaps = 5/70 (7%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 + + F+ YD +DG+I EL ++ L Q + I D+D D ++S Sbjct: 31 KDMEKMFKQYDAGRDGFIDLMELKLMM-----EKLGAPQTHLGLKNMIKEVDEDFDSKLS 85 Query: 150 FEEFCAVVGG 159 F EF + Sbjct: 86 FREFLLIFRK 95 Score = 26.1 bits (56), Expect = 8.4, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 12/30 (40%) Query: 131 QIVDKTIINADKDGDGRISFEEFCAVVGGL 160 + ++K D DG I E ++ L Sbjct: 31 KDMEKMFKQYDAGRDGFIDLMELKLMMEKL 60 >1SL8-A nrPDB Length = 191 Score = 41.1 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 30/81 (37%), Gaps = 4/81 (4%) Query: 37 SLSVEEFMSLPELQQNP---LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLR 93 L+ EE + Q + DI D D NG + E+ + E Sbjct: 90 RLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDC-E 148 Query: 94 FAFRIYDMDKDGYISNGELFQ 114 FR+ D+D+ G + E+ + Sbjct: 149 ETFRVCDIDESGQLDVDEMTR 169 Score = 39.5 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 60/157 (38%), Gaps = 29/157 (18%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFM------SLPELQQNPL-VQRVIDIFDTDGNG---- 68 I R F LD++++G +S++E + + L P +R D + G Sbjct: 15 IGRHKHMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFFGGAGMK 74 Query: 69 ---EVDFKEFIEG--------VSQFSVKGDKEQKL--RFAFRIYDMDKDGYISNGELFQV 115 E ++ E+IEG + ++S +L F I D D++G IS E Sbjct: 75 YGVETEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEWKAY 134 Query: 116 LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 K + ++T D D G++ +E Sbjct: 135 TKSAGIIQSSED-----CEETFRVCDIDESGQLDVDE 166 >3LCP-C nrPDB Length = 93 Score = 41.1 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 31/70 (44%), Gaps = 7/70 (10%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNN-------LKDTQLQQIVDKTIINADKDGDGRI 148 F+++D D + + EL + + + + +L I+D + + DK+ DG I Sbjct: 24 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 83 Query: 149 SFEEFCAVVG 158 + EF + Sbjct: 84 DYAEFAKSLQ 93 >4YGB-B nrPDB Length = 104 Score = 41.1 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 36/86 (41%), Gaps = 7/86 (8%) Query: 80 SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNN-------LKDTQLQQI 132 + ++ ++ F+++D D + + EL + + + + +L I Sbjct: 19 GRHMLEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINI 78 Query: 133 VDKTIINADKDGDGRISFEEFCAVVG 158 +D + + DK+ DG I + EF + Sbjct: 79 IDGVLRDDDKNNDGYIDYAEFAKSLQ 104 >2NCO-A nrPDB Length = 102 Score = 41.1 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Query: 93 RFAFRIYDMDKDGYISNGELFQVLKMMVGNN-LKDTQL-QQIVDKTIINADKDGDGRISF 150 R F+ YD D G + + E+ +LK + + ++ V + AD + DG +S Sbjct: 18 RRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVSL 77 Query: 151 EEFCAVV 157 EE+ ++ Sbjct: 78 EEYEDLI 84 Score = 28.4 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 32/79 (40%), Gaps = 11/79 (13%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSLPELQ--------QNPLVQRV---IDIFDTDGNGEVDF 72 + FK+ D D SG L +E L + P + V + + DT+ +G V Sbjct: 18 RRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVSL 77 Query: 73 KEFIEGVSQFSVKGDKEQK 91 +E+ + + + K + Sbjct: 78 EEYEDLIIKSLQKAGIRVE 96 Score = 26.4 bits (57), Expect = 6.6, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 29/68 (42%), Gaps = 6/68 (8%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKG------DKEQKLRFAFRIYDMDKDGYIS 108 +R+ +D DG+G++ E + + ++ ++ ++ D + DG +S Sbjct: 17 ARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVS 76 Query: 109 NGELFQVL 116 E ++ Sbjct: 77 LEEYEDLI 84 >4MEW-A nrPDB Length = 356 Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 43/109 (39%), Gaps = 7/109 (6%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPLVQRVIDIFDTDG-- 66 ++ F + + +F +LD D+ + ++ ++ R+ T G Sbjct: 179 QLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAVTRGRK 238 Query: 67 ---NGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 G++ + +F+ + K + + FR D+D DG +S EL Sbjct: 239 VQKEGKISYADFVWFLISEEDKKTP-TSIEYWFRCMDLDGDGALSMFEL 286 >1GJY-A nrPDB Length = 167 Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 28/135 (20%), Positives = 48/135 (35%), Gaps = 23/135 (17%) Query: 35 SGSLSVEEFM-----SLPELQQNPLVQR----VIDIFDTDGNGEVDFKEFIEGVSQFSVK 85 G + +E S P ++ + D D +G + F EF E + + Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLN-- 72 Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 R F +D D+ G + EL + L M G L + I + Sbjct: 73 -----GWRQHFISFDSDRSGTVDPQELQKALTTM-GFRLNPQTVNSIAKRYST------S 120 Query: 146 GRISFEEFCAVVGGL 160 G+I+F+++ A L Sbjct: 121 GKITFDDYIACCVKL 135 Score = 35.7 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 34/93 (36%), Gaps = 9/93 (9%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPLVQRVIDIFDT-DGNGEVDFKEFIE 77 + + F D D SG++ +E +L + Q V I +G++ F ++I Sbjct: 71 LNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYSTSGKITFDDYIA 130 Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNG 110 + D FR D + G ++ Sbjct: 131 CCVKLRALTDS-------FRRRDSAQQGMVNFS 156 Score = 34.2 bits (77), Expect = 0.026, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 46/130 (35%), Gaps = 18/130 (13%) Query: 28 KKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGD 87 LD D SG++ EF L + + FD+D +G VD +E + ++ + + Sbjct: 49 SMLDRDMSGTMGFNEFKELWAVLNGWRQHFI--SFDSDRSGTVDPQELQKALTTMGFRLN 106 Query: 88 KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR 147 + A R G I+ + + L D+ D G Sbjct: 107 PQTVNSIAKRY---STSGKITFDDYIACCVKLRA--LTDS---------FRRRDSAQQGM 152 Query: 148 ISF--EEFCA 155 ++F ++F Sbjct: 153 VNFSYDDFIQ 162 Score = 29.9 bits (66), Expect = 0.61, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 21/59 (35%) Query: 103 KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 +DG I EL + L + + D+D G + F EF + L+ Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLN 72 >5CSF-A nrPDB Length = 95 Score = 40.3 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 17/53 (32%), Positives = 30/53 (56%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 + EL +++ + + L++ + Q++VDK + D DGDG F+EF A V Sbjct: 30 KLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVA 82 Score = 26.1 bits (56), Expect = 7.8, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 26/39 (66%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 L E+++ +V +V++ D DG+GE DF+EF+ V+ + Sbjct: 48 LEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTT 86 >4NQG-A nrPDB Length = 197 Score = 39.9 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113 + DI D DGNG V E+I+ ++ + Q F D+D DG + E+ Sbjct: 115 WGDALFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQC-EATFAHCDLDGDGKLDVDEMT 173 Query: 114 Q 114 + Sbjct: 174 R 174 Score = 39.2 bits (90), Expect = 8e-04, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 59/157 (37%), Gaps = 29/157 (18%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSL--------PELQQNPLVQRVIDIFDTDGNGEVD 71 I R F LD++++G +++ E + + + + D G ++ Sbjct: 20 IARHKHMFNFLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVEDFFGGAGLE 79 Query: 72 FK------EFIEGVSQF-SVKGDKEQKLRFA---------FRIYDMDKDGYISNGELFQV 115 + E+IEG + + ++ K R F I D D +G +S E Q Sbjct: 80 YDKDTTWPEYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKDGNGSVSLDEWIQ- 138 Query: 116 LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 + Q + + T + D DGDG++ +E Sbjct: 139 ----YTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDE 171 Score = 28.0 bits (61), Expect = 2.3, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 32/87 (36%), Gaps = 16/87 (18%) Query: 4 EASYPLEMCSHFDADEIKRLGK------------RFKKLDLDNSGSLSVEEFMSLPE--- 48 +E E++R K F +D D +GS+S++E++ Sbjct: 85 TWPEYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKDGNGSVSLDEWIQYTHCAG 144 Query: 49 -LQQNPLVQRVIDIFDTDGNGEVDFKE 74 Q + D DG+G++D E Sbjct: 145 IQQSRGQCEATFAHCDLDGDGKLDVDE 171 >1KFU-L nrPDB Length = 699 Score = 39.9 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 25/153 (16%), Positives = 59/153 (38%), Gaps = 18/153 (11%) Query: 35 SGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRF 94 +++ E ++ +L + V F+ + +G+ + F E + + D+ + Sbjct: 462 DTFINLREVLNRFKLPPGEYI-LVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLE 520 Query: 95 AFRIYDMD--------------KDGYISNGELFQVLKMMVGNN---LKDTQLQQIVDKTI 137 F I + D +D IS EL +L+ ++ D + + Sbjct: 521 EFDISEDDIDDGVRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMV 580 Query: 138 INADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 D DG G++ +EF + + ++K+ ++ Sbjct: 581 DMLDSDGSGKLGLKEFYILWTKIQKYQKIYREI 613 Score = 36.1 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 13/104 (12%) Query: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 117 ++D+ D+DG+G++ KEF K QK + +R D+D+ G +++ E+ + L+ Sbjct: 579 MVDMLDSDGSGKLGLKEFYIL-------WTKIQKYQKIYREIDVDRSGTMNSYEMRKALE 631 Query: 118 MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 + + I+ D I F+ F + L+ Sbjct: 632 EAGFKMPCQ------LHQVIVARFADDQLIIDFDNFVRCLVRLE 669 >2HPS-A nrPDB Length = 186 Score = 39.5 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 32/155 (20%), Positives = 59/155 (38%), Gaps = 24/155 (15%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEE----------FMSLPELQQNPLVQRVIDIFDTDGNG 68 ++++ R +++D+ G +S E+ L + Q + + D G Sbjct: 12 HLRKMKTRMQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQLGLA 71 Query: 69 E---VDFKEFIEGVSQFSVKGDKEQKLRFA------FRIYDMDKDGYISNGELFQVLKMM 119 + +E + +K E+K + D DKDGY+S E L+ Sbjct: 72 PGVRISVEEAAVNATDSLLKMKGEEKAMAVIQSLIMYDCIDTDKDGYVSLPEFKAFLQA- 130 Query: 120 VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 VG +L D + D + +G+IS +EF Sbjct: 131 VGPDLTDDK----AITCFNTLDFNKNGQISRDEFL 161 Score = 34.9 bits (79), Expect = 0.016, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 30 LDLDNSGSLSVEEFMSLPELQQNPLVQR----VIDIFDTDGNGEVDFKEFIEGVSQFSVK 85 +D D G +S+ EF + + L + D + NG++ EF+ V+ F Sbjct: 111 IDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFLVTVNDFLF- 169 Query: 86 GDKEQKLRFAF 96 G +E L AF Sbjct: 170 GLEETALANAF 180 >4HRG-A nrPDB Length = 115 Score = 39.5 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 + + F F + DK GY++ +L +++ L++ + VDK + + D+ DG++ Sbjct: 11 ETMMFTFHKFAGDK-GYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKDLDQCRDGKVG 69 Query: 150 FEEFCAVVGGLDI 162 F+ F +++ GL I Sbjct: 70 FQSFFSLIAGLTI 82 >4FTG-A nrPDB Length = 96 Score = 39.2 bits (90), Expect = 8e-04, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 + + F F + DK GY++ +L +++ L++ + VDK + + D+ DG++ Sbjct: 9 ETMMFTFHKFAGDK-GYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKDLDQCRDGKVG 67 Query: 150 FEEFCAVVGGLDI 162 F+ F +++ GL I Sbjct: 68 FQSFFSLIAGLTI 80 >1F4Q-A nrPDB Length = 165 Score = 39.2 bits (90), Expect = 9e-04, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 50/135 (37%), Gaps = 23/135 (17%) Query: 35 SGSLSVEEFMS-LPELQQN--------PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVK 85 G + EE L + N + +I + D D G++ F F E + + Sbjct: 13 DGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNA- 71 Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD 145 + F D D G + + EL Q + ++G L L IV + N Sbjct: 72 ------WKENFMTVDQDGSGTVEHHELRQAIG-LMGYRLSPQTLTTIVKRYSKN------ 118 Query: 146 GRISFEEFCAVVGGL 160 GRI F+++ A L Sbjct: 119 GRIFFDDYVACCVKL 133 Score = 34.5 bits (78), Expect = 0.023, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 24/70 (34%), Gaps = 2/70 (2%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDT--DGNGEVDFKEFIE 77 + + F +D D SG++ E L L + + NG + F +++ Sbjct: 69 LNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA 128 Query: 78 GVSQFSVKGD 87 + D Sbjct: 129 CCVKLRALTD 138 >2FCE-A nrPDB Length = 70 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 34/66 (51%), Gaps = 5/66 (7%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 + AF+++D + G +S G+L +L + G L D + VD+ + + D +G I Sbjct: 5 EDFVKAFQVFDKESTGKVSVGDLRYMLTGL-GEKLTDAE----VDELLKGVEVDSNGEID 59 Query: 150 FEEFCA 155 +++F Sbjct: 60 YKKFIE 65 Score = 32.6 bits (73), Expect = 0.088, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDF 72 + + K F+ D +++G +SV + + L V ++ + D NGE+D+ Sbjct: 1 KAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDY 60 Query: 73 KEFIEGVSQ 81 K+FIE V + Sbjct: 61 KKFIEDVLR 69 >3DF0-A nrPDB Length = 714 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 26/152 (17%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPE--LQQNPLVQR----------VIDIFDTDGNGEV 70 + F +L +S E ++ L + ++ ++D+ D DG+G++ Sbjct: 534 FRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKL 592 Query: 71 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ 130 KEF K QK + +R D+D+ G +++ E+ + L+ G L Q Sbjct: 593 GLKEFYIL-------WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA-GFKLPCQLHQ 644 Query: 131 QIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 IV + D + I F+ F + L+I Sbjct: 645 VIVARF-----ADDELIIDFDNFVRCLVRLEI 671 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 39/94 (41%), Gaps = 10/94 (10%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL---VQRVIDIFDTDGNGEVDFKEFI 76 I++ K ++++D+D SG+++ E E L + +VI D +DF F+ Sbjct: 604 IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFV 663 Query: 77 EGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNG 110 + + + L F+ D + G I Sbjct: 664 RCLVRL-------EILFKIFKQLDPENTGTIQLD 690 Score = 34.2 bits (77), Expect = 0.033, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Query: 103 KDGYISNGELFQVLKMMVGNN---LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 +D IS EL +L+ ++ D + + D+DG G++ +EF + Sbjct: 544 EDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTK 603 Query: 160 LDIHKKMVVDV 170 + ++K+ ++ Sbjct: 604 IQKYQKIYREI 614 >2Y5I-A nrPDB Length = 99 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 29/57 (50%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S GEL ++L + + L + +V+K + + D + D + F EF +V L + Sbjct: 28 KLSKGELKELLNAELTDFLMSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVAALTV 84 Score = 27.6 bits (60), Expect = 2.9, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 24/39 (61%) Query: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 L + LV+++++ D++ + EVDF EF+ V+ +V Sbjct: 46 LMSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVAALTV 84 >4MSP-A nrPDB Length = 200 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 3/64 (4%) Query: 93 RFAFRIYDMDKDGYISNGELFQVLKMMV---GNNLKDTQLQQIVDKTIINADKDGDGRIS 149 +F+ D++ D +S E+ LK G + ++ +V+ D+D DG IS Sbjct: 130 HESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFIS 189 Query: 150 FEEF 153 EF Sbjct: 190 AREF 193 >1UHK-A nrPDB Length = 191 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 24/61 (39%), Gaps = 1/61 (1%) Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113 + DI D D NG + E+ + E FR+ D+D+ G + E+ Sbjct: 110 WGDALFDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDC-EETFRVCDIDESGQLDVDEMT 168 Query: 114 Q 114 + Sbjct: 169 R 169 Score = 38.0 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 33/159 (20%), Positives = 58/159 (36%), Gaps = 33/159 (20%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFM------SLPELQQNPL-VQRVIDIFDTDGNG---- 68 I R F LD++++G +S++E + + L P +R D + G Sbjct: 15 IGRHKHMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFFGGAGMK 74 Query: 69 ---EVDFKEFIEGVSQFSVKGDKEQKLRF------------AFRIYDMDKDGYISNGELF 113 E D+ +IEG + D+ +K F I D D++G I+ E Sbjct: 75 YGVETDWPAYIEG--WKKLATDELEKYAKNEPTLIRIWGDALFDIVDKDQNGAITLDEWK 132 Query: 114 QVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 K + ++T D D G++ +E Sbjct: 133 AYTKAAGIIQSSED-----CEETFRVCDIDESGQLDVDE 166 >4I5K-A nrPDB Length = 285 Score = 38.4 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 19/109 (17%), Positives = 45/109 (41%), Gaps = 7/109 (6%) Query: 10 EMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNP-LVQRVI-----DIFD 63 ++ +F + + +F +LD D+ +S + + + +++R+ Sbjct: 105 QITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKT 164 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 G + + +F+ + K + + + FR D+D DG +S EL Sbjct: 165 IQKEGRMSYADFVWFLISEEDKRNP-TSIEYWFRCMDVDGDGVLSMYEL 212 >2MJW-B nrPDB Length = 94 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 29/55 (52%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 ++ GEL +++ + L+ + + VDK + + D +GD ++ F EF V + Sbjct: 27 TLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAI 81 Score = 27.2 bits (59), Expect = 3.7, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 20/41 (48%) Query: 44 MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSV 84 L + V +++ D +G+ +VDF EFI V+ + Sbjct: 43 GFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAITS 83 >6MI5-X nrPDB Length = 117 Score = 37.6 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 26/101 (25%), Positives = 38/101 (37%), Gaps = 29/101 (28%) Query: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 I FD D +G +D KE + S AF D DKDG + EL Sbjct: 9 IAAFDPDKDGTIDLKEALAAGSA-------------AFDKLDPDKDGTLDAKELK----- 50 Query: 119 MVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159 + + L+++ D D DG + +E+ A V Sbjct: 51 ---GRVSEADLKKL--------DPDNDGTLDKKEYLAAVEA 80 Score = 37.2 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 32/87 (36%), Gaps = 20/87 (22%) Query: 26 RFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVK 85 F KLD D G+L +E + + D D +G +D KE++ V Sbjct: 32 AFDKLDPDKDGTLDAKELKGRVS-------EADLKKLDPDNDGTLDKKEYLAAV------ 78 Query: 86 GDKEQKLRFAFRIYDMDKDGYISNGEL 112 F+ + D DG I EL Sbjct: 79 -------EAQFKAANPDNDGTIDAREL 98 Score = 33.4 bits (75), Expect = 0.052, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 39/124 (31%), Gaps = 37/124 (29%) Query: 29 KLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDK 88 D D G++ ++E ++ D D D +G +D KE VS+ + Sbjct: 11 AFDPDKDGTIDLKEALAAGSA--------AFDKLDPDKDGTLDAKELKGRVSEADL---- 58 Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRI 148 + D D DG + E V+ A+ D DG I Sbjct: 59 --------KKLDPDNDGTLDKKEYLAA-----------------VEAQFKAANPDNDGTI 93 Query: 149 SFEE 152 E Sbjct: 94 DARE 97 >2MA2-A nrPDB Length = 81 Score = 37.6 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 8/61 (13%) Query: 52 NPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGE 111 +V+ V FD DG+G + +EF F AF D ++DG IS E Sbjct: 12 EKMVESVFRNFDVDGDGHISQEEFQIIRGNFP--------YLSAFGDLDQNQDGCISREE 63 Query: 112 L 112 + Sbjct: 64 M 64 Score = 35.3 bits (80), Expect = 0.012, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 21/51 (41%), Gaps = 3/51 (5%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 F+ D+D G +S EEF + P + D + +G + +E Sbjct: 16 ESVFRNFDVDGDGHISQEEFQIIR--GNFPYL-SAFGDLDQNQDGCISREE 63 Score = 35.3 bits (80), Expect = 0.013, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 28/67 (41%), Gaps = 12/67 (17%) Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRI 148 E+ + FR +D+D DG+IS E + + + D++ DG I Sbjct: 12 EKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLS------------AFGDLDQNQDGCI 59 Query: 149 SFEEFCA 155 S EE + Sbjct: 60 SREEMVS 66 Score = 34.5 bits (78), Expect = 0.022, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 18/30 (60%) Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAV 156 ++++V+ N D DGDG IS EEF + Sbjct: 9 EHIEKMVESVFRNFDVDGDGHISQEEFQII 38 >2KGR-A nrPDB Length = 111 Score = 37.6 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 38/84 (45%), Gaps = 7/84 (8%) Query: 79 VSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII 138 V++++V K R F +D G+++ + +L ++ + Q + Sbjct: 3 VAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTIL-------MQSSLPQAQLASIWN 55 Query: 139 NADKDGDGRISFEEFCAVVGGLDI 162 +D D DG+++ EEF + +D+ Sbjct: 56 LSDIDQDGKLTAEEFILAMHLIDV 79 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 27/60 (45%), Gaps = 2/60 (3%) Query: 22 RLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ--RVIDIFDTDGNGEVDFKEFIEGV 79 + + F D SG L+ + ++ P Q + ++ D D +G++ +EFI + Sbjct: 15 KYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAM 74 Score = 28.4 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 11/89 (12%), Positives = 31/89 (34%), Gaps = 7/89 (7%) Query: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 +++ + D +G + + + + +L + + D+D+DG ++ E Sbjct: 17 RQLFNSHDKTMSGHLTGP---QARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILA 73 Query: 116 L----KMMVGNNLKDTQLQQIVDKTIINA 140 + M G L + + + Sbjct: 74 MHLIDVAMSGQPLPPVLPPEYIPPSFRRV 102 Score = 26.8 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 15/34 (44%), Gaps = 3/34 (8%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM 44 M S ++ + D+D G L+ EEF+ Sbjct: 41 MQSSLPQAQLASIWN---LSDIDQDGKLTAEEFI 71 >1NP8-A nrPDB Length = 159 Score = 37.2 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 32/157 (20%), Positives = 66/157 (42%), Gaps = 26/157 (16%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSL--------PELQQN----PLVQRVIDIFDT 64 ++E ++ K F +L + +S E M++ P+L+ + + ++ + D+ Sbjct: 7 SEEERQFRKLFVQL-AGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDS 65 Query: 65 DGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNL 124 D G++ F+EF + +K + ++ +D D+ G I + EL + Sbjct: 66 DTTGKLGFEEF-------KYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAA----- 113 Query: 125 KDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD 161 L Q + II D G + F+ F + + LD Sbjct: 114 -GFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLD 149 Score = 34.2 bits (77), Expect = 0.030, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 10/84 (11%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF---DTDGNGEVDFKEFI 76 IK+ +K+ D D SG++ E E L Q + + +D G +DF FI Sbjct: 83 IKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFI 142 Query: 77 EGVSQFSVKGDKEQKLRFAFRIYD 100 + + + AFR D Sbjct: 143 SCLVRLDA-------MFRAFRSLD 159 >2SAS-A nrPDB Length = 185 Score = 36.5 bits (83), Expect = 0.005, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Query: 89 EQKLRFAFRIY-DMDKDGYISNGELFQVLKMMVGNN---LKDTQ-------LQQIVDKTI 137 +QK++F F + DM+ DG I + + ++ N L D L+ Sbjct: 7 KQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRDLK 66 Query: 138 INADKDGDGRISFEEFCAVVGGL 160 AD + D +S+EE+ A+ Sbjct: 67 GRADINKDDVVSWEEYLAMWEKT 89 Score = 32.2 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 23/140 (16%), Positives = 50/140 (35%), Gaps = 23/140 (16%) Query: 19 EIKRLGKRFKKL-DLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77 + +++ F D+++ GS+ +F + ++ + G + ++ Sbjct: 6 QKQKIKFTFDFFLDMNHDGSIQDNDF------------EDMMTRYKEVNKGSLSDADY-- 51 Query: 78 GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL----QQIV 133 S++ E + R D++KD +S E + + + L Q + Sbjct: 52 ----KSMQASLEDEWRDLKGRADINKDDVVSWEEYLAMWEKTIATCKSVADLPAWCQNRI 107 Query: 134 DKTIINADKDGDGRISFEEF 153 D GDG + EEF Sbjct: 108 PFLFKGMDVSGDGIVDLEEF 127 >6DS2-B nrPDB Length = 114 Score = 36.1 bits (82), Expect = 0.007, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 34/56 (60%), Gaps = 1/56 (1%) Query: 106 YISNGELFQVLKMMVGNNLK-DTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 ++ GE ++++ + N LK + + +++++ + + D + D ++SFEEF ++ L Sbjct: 31 TLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARL 86 Score = 28.8 bits (63), Expect = 1.1, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 32/68 (47%), Gaps = 12/68 (17%) Query: 37 SLSVEEFMSL----------PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKG 86 +L+ EF L E + +++ +++ DT+ + ++ F+EFI +++ + Sbjct: 31 TLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARLT--W 88 Query: 87 DKEQKLRF 94 +K+ Sbjct: 89 ASHEKMHE 96 >1KQV-A nrPDB Length = 79 Score = 35.7 bits (81), Expect = 0.009, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 18/29 (62%) Query: 133 VDKTIINADKDGDGRISFEEFCAVVGGLD 161 +D+ DK+GDG +SFEEF +V + Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKKIS 78 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 15/24 (62%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSL 46 L + F++LD + G +S EEF L Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVL 73 Score = 26.8 bits (58), Expect = 4.3, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 19/35 (54%) Query: 49 LQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFS 83 L+ + + + D +G+GEV F+EF V + S Sbjct: 44 LKGMSTLDELFEELDKNGDGEVSFEEFQVLVKKIS 78 >5LPU-C nrPDB Length = 104 Score = 35.7 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 24/53 (45%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 ++ EL ++L + + L + K + N D + D + F+E+C + Sbjct: 31 KLNKSELKELLTRELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYCVFLS 83 >6EAZ-A nrPDB Length = 379 Score = 35.7 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 18/112 (16%), Positives = 41/112 (36%), Gaps = 17/112 (15%) Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGE---LFQVLKMM 119 D G + + E++ + ++ AF++ D+D + I E L +++ Sbjct: 95 DLGDKGVISYTEYLFLL---TILTKPHSGFHVAFKMLDVDGNEMIERKEFVKLQKIISKQ 151 Query: 120 VGNNLKDTQLQQIVDKTIINADKD-----------GDGRISFEEFCAVVGGL 160 G T + D T+ + G+ ++ ++EF + L Sbjct: 152 DGFKTVKTNETEYQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFMENL 203 Score = 34.9 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 36/81 (44%) Query: 37 SLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAF 96 S+S++EF S + + + + V EF V + + + L F Sbjct: 256 SISLDEFKSFCHFTTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSDNLLDTVF 315 Query: 97 RIYDMDKDGYISNGELFQVLK 117 +I+D+D D +S+GE VLK Sbjct: 316 KIFDLDGDECLSHGEFLGVLK 336 Score = 28.0 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 21/49 (42%), Gaps = 4/49 (8%) Query: 110 GELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 E + +K+ G L D ++D D DGD +S EF V+ Sbjct: 292 AEFKRAVKVATGQELSDN----LLDTVFKIFDLDGDECLSHGEFLGVLK 336 Score = 26.8 bits (58), Expect = 4.7, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 37/96 (38%), Gaps = 23/96 (23%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQ----------------QNPLVQRV-------I 59 FK LD+D + + +EF+ L ++ Q+P V+ + Sbjct: 121 FHVAFKMLDVDGNEMIERKEFVKLQKIISKQDGFKTVKTNETEYQDPTVKEPGVNTTLQV 180 Query: 60 DIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFA 95 F G ++ +KEF + + + + L+F+ Sbjct: 181 RFFGKRGEKKLHYKEFRRFMENLQTEVQEMEFLQFS 216 >4CFQ-A nrPDB Length = 91 Score = 35.7 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 26/57 (45%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 ++ EL ++L + + L + K + N D + D + F+E+C + + + Sbjct: 31 KLNKSELKELLTRELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYCVFLSSIAM 87 >6DU8-A nrPDB Length = 805 Score = 35.3 bits (80), Expect = 0.013, Method: Composition-based stats. Identities = 10/68 (14%), Positives = 31/68 (45%), Gaps = 1/68 (1%) Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 G E+ F++F + + + +L F +D D + + E ++ + + + Sbjct: 612 GEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVA 671 Query: 126 -DTQLQQI 132 +T+++++ Sbjct: 672 LNTEIEKL 679 Score = 32.2 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 15/40 (37%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ 56 EI L F K D D + L +E + + + V Sbjct: 632 EHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVA 671 >5W1A-B nrPDB Length = 155 Score = 34.9 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 28/147 (19%), Positives = 60/147 (40%), Gaps = 9/147 (6%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVIDIFDTDGNGE--VDF 72 E++ + F+ + G + + L L NP + + + T E + Sbjct: 5 PKREVENVEFVFEVMGSPGEG-IDAVDLGDALRALNLNPTLALIEKLGGTKKRNEKKIKL 63 Query: 73 KEFIEGVSQFSVKGDK--EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ 130 EF+ SQ + ++ + ++YD +++G + EL L + G +L D Q++ Sbjct: 64 DEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLAL-GESLDDEQVE 122 Query: 131 QIVDKTIINADKDGDGRISFEEFCAVV 157 + + +D +G I + F A + Sbjct: 123 TLFADCMDP--EDDEGFIPYSPFLARM 147 >2AUC-A nrPDB Length = 126 Score = 34.9 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 46/109 (42%), Gaps = 8/109 (7%) Query: 47 PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGY 106 +L P I D G+ + +++++E ++ D ++L F +D + G+ Sbjct: 23 RKLGLAPSSTDEKKIRDLYGDS-LTYEQYLEYLTMCVHDRDNMEELIKMFSHFDNNSSGF 81 Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 ++ ++ +L G+ L + + ++ RI+++ FC Sbjct: 82 LTKNQMKNILTT-WGDALTEQEANDALNAFSSE------DRINYKLFCE 123 Score = 27.2 bits (59), Expect = 3.9, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 26/64 (40%), Gaps = 2/64 (3%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPEL-QQNPLVQRVIDIFDT-DGNGEVDFK 73 D D ++ L K F D ++SG L+ + ++ Q D + +++K Sbjct: 60 DRDNMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQEANDALNAFSSEDRINYK 119 Query: 74 EFIE 77 F E Sbjct: 120 LFCE 123 >4YBH-B nrPDB Length = 92 Score = 34.9 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 34/59 (57%), Gaps = 6/59 (10%) Query: 106 YISNGELFQVLKMMV--GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S EL ++++ + G+ L+D ++ ++++ D++ D ++F+E+ +G L + Sbjct: 30 TLSKKELKELIQKELTIGSKLQDAEIARLMEDL----DRNKDQEVNFQEYVTFLGALAL 84 >3NSO-A nrPDB Length = 101 Score = 34.5 bits (78), Expect = 0.020, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 23/58 (39%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 + EL ++L+ + + +K + D + D + F E+ + L ++ Sbjct: 28 KLCQAELKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSLACLCLY 85 >6AGH-A nrPDB Length = 339 Score = 34.2 bits (77), Expect = 0.026, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 34/81 (41%) Query: 37 SLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAF 96 S+S++EF S + + + + V EF V + + L F Sbjct: 253 SISLDEFKSFCHFTTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSNNILDTVF 312 Query: 97 RIYDMDKDGYISNGELFQVLK 117 +I+D+D D +S+ E VLK Sbjct: 313 KIFDLDGDECLSHEEFLGVLK 333 Score = 32.6 bits (73), Expect = 0.084, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 42/112 (37%), Gaps = 17/112 (15%) Query: 63 DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK----- 117 D G + + E++ + ++ AF++ D D + I E F++ K Sbjct: 92 DLGDKGLISYTEYLFLL---TILTKPHSGFHVAFKMLDTDGNEMIEKREFFKLQKIISKQ 148 Query: 118 -MMVGNNLKDTQLQQIVDK--------TIINADKDGDGRISFEEFCAVVGGL 160 ++ +T Q+ + K + K G ++ ++EF + L Sbjct: 149 DDLMTVKTNETGYQEAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFMENL 200 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 4/49 (8%) Query: 110 GELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 E + +K+ G L + I+D D DGD +S EEF V+ Sbjct: 289 AEFKRAVKVATGQELSNN----ILDTVFKIFDLDGDECLSHEEFLGVLK 333 >4NSC-A nrPDB Length = 401 Score = 34.2 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 24/48 (50%), Gaps = 3/48 (6%) Query: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 G + F ++I + S ++ AF+++D++ DG + E QV Sbjct: 127 GLISFSDYIFLTTVLS---TPQRNFEIAFKMFDLNGDGEVDMEEFEQV 171 Score = 29.9 bits (66), Expect = 0.53, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 14/30 (46%) Query: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAV 156 + Q+ + D +GDG + EEF V Sbjct: 142 STPQRNFEIAFKMFDLNGDGEVDMEEFEQV 171 Score = 29.9 bits (66), Expect = 0.58, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 20/36 (55%) Query: 26 RFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDI 61 F D D +G LS +EF+S+ + + +++ D+ Sbjct: 341 VFALFDCDGNGELSNKEFVSIMKQRLMRGLEKPKDM 376 Score = 29.1 bits (64), Expect = 0.84, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 15/32 (46%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL 54 FK DL+ G + +EEF + + ++ Sbjct: 148 FEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQT 179 Score = 28.8 bits (63), Expect = 1.1, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 36/108 (33%), Gaps = 6/108 (5%) Query: 11 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEV 70 A + ++L K F + G L+ +E + +N F + Sbjct: 263 QSKKLTAMQ-RQLKKHF----KEGKG-LTFQEVENFFTFLKNINDVDTALSFYHMAGASL 316 Query: 71 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 D + + + F ++D D +G +SN E ++K Sbjct: 317 DKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQ 364 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 45/132 (34%), Gaps = 20/132 (15%) Query: 35 SGSLSVEEFMSLP------ELQQNPLVQRVIDIFDTDGNGEV--DFKEFIEGVSQFSVKG 86 G ++ +F + + ++ +QR + +G G + + F + + Sbjct: 244 DGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVD 303 Query: 87 DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 A D + QV + + L D + D D DG+G Sbjct: 304 TALSFYHMAGASLDK--------VTMQQVARTVAKVELSDH----VCDVVFALFDCDGNG 351 Query: 147 RISFEEFCAVVG 158 +S +EF +++ Sbjct: 352 ELSNKEFVSIMK 363 >4DUQ-A nrPDB Length = 98 Score = 33.8 bits (76), Expect = 0.038, Method: Composition-based stats. Identities = 9/57 (15%), Positives = 31/57 (54%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S GE+ ++L + + + + ++ + K + + D++ D ++ F+E+ + + + Sbjct: 29 KLSKGEMKELLHKELPSFVGEKVDEEGLKKLMGSLDENSDQQVDFQEYAVFLALITV 85 >4AOM-A nrPDB Length = 146 Score = 33.4 bits (75), Expect = 0.054, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL 129 + +++++E +S D ++L F +D + GY++ ++ +L G+ L D + Sbjct: 64 LTYEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTT-WGDALTDQEA 122 Query: 130 QQIVDKTIINADKD 143 ++ + D Sbjct: 123 IDALNAFSSEDNID 136 Score = 27.2 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 26/64 (40%), Gaps = 2/64 (3%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPEL-QQNPLVQRVIDIFDT-DGNGEVDFK 73 D D ++ L K F D + +G L+ + ++ Q ID + +D+K Sbjct: 79 DKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDNIDYK 138 Query: 74 EFIE 77 F E Sbjct: 139 LFCE 142 >5HLO-A nrPDB Length = 94 Score = 33.4 bits (75), Expect = 0.057, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 21/50 (42%) Query: 113 FQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 LK ++ ++ D D + DG ++F+EF +V + + Sbjct: 32 RDDLKKLLETECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGV 81 >6AGI-A nrPDB Length = 382 Score = 33.0 bits (74), Expect = 0.065, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 31/80 (38%) Query: 38 LSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFR 97 ++ +EF S + N + + + EF V + + F+ Sbjct: 291 ITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFK 350 Query: 98 IYDMDKDGYISNGELFQVLK 117 I+D+DKD +S E ++K Sbjct: 351 IFDVDKDDQLSYKEFIGIMK 370 Score = 31.8 bits (71), Expect = 0.13, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 25/77 (32%), Gaps = 3/77 (3%) Query: 37 SLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAF 96 SLS +E + + G + + E++ + + R AF Sbjct: 55 SLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLL---CILTKPHAGFRIAF 111 Query: 97 RIYDMDKDGYISNGELF 113 ++D D + + E Sbjct: 112 NMFDTDGNEMVDKKEFL 128 Score = 31.5 bits (70), Expect = 0.19, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 21/52 (40%), Gaps = 4/52 (7%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 I E + + + G +V+ D D D ++S++EF ++ Sbjct: 323 IGQDEFKRAVYVATGLKFSPH----LVNTVFKIFDVDKDDQLSYKEFIGIMK 370 Score = 26.4 bits (57), Expect = 5.8, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 5/55 (9%) Query: 37 SLSVEEFMSL----PELQQNP-LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKG 86 S+ +EF L+ +P LV V IFD D + ++ +KEFI + +G Sbjct: 322 SIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRG 376 Score = 26.1 bits (56), Expect = 7.6, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 13/25 (52%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSLPE 48 FK D+D LS +EF+ + + Sbjct: 346 NTVFKIFDVDKDDQLSYKEFIGIMK 370 Score = 26.1 bits (56), Expect = 8.7, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 15/35 (42%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQR 57 F D D + + +EF+ L E+ + +R Sbjct: 107 FRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKR 141 >2JTT-A nrPDB Length = 90 Score = 33.0 bits (74), Expect = 0.073, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 34/59 (57%), Gaps = 6/59 (10%) Query: 106 YISNGELFQVLKMMV--GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S EL ++++ + G+ L+D ++ +++D D++ D ++F+E+ +G L + Sbjct: 28 TLSKKELKELIQKELTIGSKLQDAEIVKLMDDL----DRNKDQEVNFQEYITFLGALAM 82 >2VTG-A nrPDB Length = 150 Score = 32.6 bits (73), Expect = 0.078, Method: Composition-based stats. Identities = 8/66 (12%), Positives = 30/66 (45%), Gaps = 4/66 (6%) Query: 18 DEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDFK 73 +++ +++ + DL+N G + + + E P ++++I + + ++ Sbjct: 47 EKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYR 106 Query: 74 EFIEGV 79 +F+ + Sbjct: 107 DFVNMM 112 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 9/68 (13%), Positives = 31/68 (45%), Gaps = 5/68 (7%) Query: 92 LRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFE 151 + + +D++ +G I L ++++ + G ++++++ + IS+ Sbjct: 52 FKEKYMEFDLNNEGEIDLMSLKRMMEKL-GVPKTHLEMKKMISEVTGGV----SDTISYR 106 Query: 152 EFCAVVGG 159 +F ++ G Sbjct: 107 DFVNMMLG 114 >2MHH-A nrPDB Length = 96 Score = 31.8 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 29/71 (40%), Gaps = 3/71 (4%) Query: 53 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGEL 112 +Q + D + + +DF E+ + + +G + + F YD+D D + E Sbjct: 18 ADIQEALAHADANADQHLDFDEWRQ---ELKCRGHADADIEAVFAKYDVDGDRVLDAEEQ 74 Query: 113 FQVLKMMVGNN 123 ++ + G Sbjct: 75 MKMAHDLEGQK 85 >2G2B-A nrPDB Length = 150 Score = 31.8 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 33/71 (46%), Gaps = 7/71 (9%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR-I 148 + + + +D++ +G I L ++L+ + G +L++++ + G G Sbjct: 51 EGFKEKYMEFDLNGNGDIDIMSLKRMLEKL-GVPKTHLELKKLIGEV-----SSGSGETF 104 Query: 149 SFEEFCAVVGG 159 S+ +F ++ G Sbjct: 105 SYPDFLRMMLG 115 Score = 31.1 bits (69), Expect = 0.28, Method: Composition-based stats. Identities = 7/64 (10%), Positives = 27/64 (42%), Gaps = 4/64 (6%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDFKEF 75 ++ +++ + DL+ +G + + + E P ++++I + + +F Sbjct: 50 LEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDF 109 Query: 76 IEGV 79 + + Sbjct: 110 LRMM 113 >5C5V-A nrPDB Length = 342 Score = 31.8 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 36/68 (52%), Gaps = 8/68 (11%) Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDG-DGR 147 ++ + F +D+ GY++ ++ +V + + G N+ D ++ + A+ + DG Sbjct: 6 KKIMSRLFSAFDVTHLGYLTPDKVEEVCRYL-GRNMSDGDVKAM------KAEINAIDGH 58 Query: 148 ISFEEFCA 155 ++FE+F A Sbjct: 59 VTFEKFWA 66 >5NRM-B nrPDB Length = 66 Score = 31.8 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 28/57 (49%), Gaps = 5/57 (8%) Query: 100 DMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAV 156 D+D +G I++ + + ++G NLKD + + D +GD I+ +F + Sbjct: 4 DVDGNGSINSIDFALMRNYLLG-NLKDFPAEDDIK----AGDLNGDKSININDFAIM 55 >5CUY-A nrPDB Length = 414 Score = 31.5 bits (70), Expect = 0.18, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 36/68 (52%), Gaps = 8/68 (11%) Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDG-DGR 147 ++ + F +D+ GY++ ++ +V + + G N+ D ++ + A+ + DG Sbjct: 78 KKIMSRLFSAFDVTHLGYLTPDKVEEVCRYL-GRNMSDGDVKAM------KAEINAIDGH 130 Query: 148 ISFEEFCA 155 ++FE+F A Sbjct: 131 VTFEKFWA 138 >1C07-A nrPDB Length = 95 Score = 31.5 bits (70), Expect = 0.18, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 26/72 (36%), Gaps = 2/72 (2%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMS--LPELQQNPLVQRVIDIFDTDGNGEVDFK 73 E + + F K D D G +S E L + L+ + + DT G++ Sbjct: 5 SPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKLSKD 64 Query: 74 EFIEGVSQFSVK 85 +F S K Sbjct: 65 QFALAFHLISQK 76 Score = 26.4 bits (57), Expect = 6.9, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 27/67 (40%), Gaps = 7/67 (10%) Query: 88 KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR 147 ++ K F D D DG++S E+ ++ LK ++ D G+ Sbjct: 8 EKAKYDEIFLKTDKDMDGFVSGLEVREIF-------LKTGLPSTLLAHIWSLCDTKDCGK 60 Query: 148 ISFEEFC 154 +S ++F Sbjct: 61 LSKDQFA 67 >4C0K-A nrPDB Length = 423 Score = 31.5 bits (70), Expect = 0.21, Method: Composition-based stats. Identities = 35/151 (23%), Positives = 56/151 (37%), Gaps = 14/151 (9%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-PELQQNPLVQRVIDIF---------D 63 + K L + FK D+D L+ E PL +++D D Sbjct: 6 ELTSACKKSLVRIFKICDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVIQKNVPD 65 Query: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFA-FRIYDMDKDGYISNGELFQVLKMMVGN 122 N V K F+ F +G E +A R + + + L LK+ G+ Sbjct: 66 GIYNDAVTLKGFLFLHCLFIQRGRNET--TWAVLRRFGYNDQLEMCQEYLRPPLKIPPGS 123 Query: 123 NLK-DTQLQQIVDKTIINADKDGDGRISFEE 152 + + + QQ + D+DGDG +S EE Sbjct: 124 STELSHRGQQFLIAVFERYDRDGDGALSPEE 154 Score = 30.7 bits (68), Expect = 0.33, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 16/41 (39%) Query: 8 PLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPE 48 P + + L F++ D D G+LS EE L Sbjct: 120 PPGSSTELSHRGQQFLIAVFERYDRDGDGALSPEEHKMLFS 160 >5CUU-A nrPDB Length = 414 Score = 31.1 bits (69), Expect = 0.22, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 35/85 (41%), Gaps = 8/85 (9%) Query: 73 KEFIEGVSQFSVKGDKEQKLRFA--FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQ 130 EF +K A F +D+ + GY+ ++ + K + G + + ++ Sbjct: 59 TEFDLVAYGKDEFTLSMEKRVMARMFSAFDVTQLGYLEERKIEHMCKYL-GRVMNEDDVK 117 Query: 131 QIVDKTIINADKDGDGRISFEEFCA 155 Q+ + DG I+FE+F A Sbjct: 118 QMKSEINAI-----DGHITFEKFWA 137 >3A8R-A nrPDB Length = 179 Score = 31.1 bits (69), Expect = 0.22, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 25/72 (34%), Gaps = 12/72 (16%) Query: 22 RLGKRFKKLDLDNSGSLSVEEFMSLPELQQN------------PLVQRVIDIFDTDGNGE 69 RL F +D + G L+ EE + L + +++ D G Sbjct: 99 RLRTFFDMVDKNADGRLTAEEVKEIIALSASANKLSKIKERADEYTALIMEELDPTNLGY 158 Query: 70 VDFKEFIEGVSQ 81 ++ ++ + Q Sbjct: 159 IEMEDLEALLLQ 170 Score = 31.1 bits (69), Expect = 0.26, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 33/68 (48%), Gaps = 5/68 (7%) Query: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDK----TIINADKDG 144 + +LR F + D + DG ++ E+ +++ + N K +++++ D+ + D Sbjct: 97 DNRLRTFFDMVDKNADGRLTAEEVKEIIALSASAN-KLSKIKERADEYTALIMEELDPTN 155 Query: 145 DGRISFEE 152 G I E+ Sbjct: 156 LGYIEMED 163 Score = 29.5 bits (65), Expect = 0.72, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 19/52 (36%), Gaps = 5/52 (9%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVG 158 ++ EL L D + DK+ DGR++ EE ++ Sbjct: 79 LTKDELKDFY-----EQLTDQGFDNRLRTFFDMVDKNADGRLTAEEVKEIIA 125 >2JXC-A nrPDB Length = 100 Score = 31.1 bits (69), Expect = 0.23, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 23/54 (42%), Gaps = 7/54 (12%) Query: 104 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 +G++S ++ VL L I+ + +D D DG + +EF + Sbjct: 28 NGFLSGDKVKPVL-------LNSKLPVDILGRVWELSDIDHDGMLDRDEFAVAM 74 >1WY9-A nrPDB Length = 147 Score = 31.1 bits (69), Expect = 0.25, Method: Composition-based stats. Identities = 8/64 (12%), Positives = 26/64 (40%), Gaps = 4/64 (6%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDFKEF 75 ++ ++ + DL+ +G + + + E P ++R+I + + +F Sbjct: 47 LEAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSGSEETFSYSDF 106 Query: 76 IEGV 79 + + Sbjct: 107 LRMM 110 Score = 30.7 bits (68), Expect = 0.30, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 35/70 (50%), Gaps = 9/70 (12%) Query: 94 FAFRI----YDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 AF++ +D++ +G I L ++L+ + G +L++++ + +++ S Sbjct: 48 EAFKVKYMEFDLNGNGDIDIMSLKRMLEKL-GVPKTHLELKRLIREVSSGSEE----TFS 102 Query: 150 FEEFCAVVGG 159 + +F ++ G Sbjct: 103 YSDFLRMMLG 112 >5VP3-A nrPDB Length = 206 Score = 30.7 bits (68), Expect = 0.29, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 3/48 (6%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPE 48 +GN + +E ++RL KRF DLD G ++++E M P+ Sbjct: 17 VGNTWKFNVEDVHP---KMLERLYKRFDTFDLDTDGKMTMDEIMYWPD 61 >5KU1-A nrPDB Length = 424 Score = 30.3 bits (67), Expect = 0.43, Method: Composition-based stats. Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 16/146 (10%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN-PLVQRVIDIF---------DTDGNGE 69 IK L + FK D DN G+L+ E + N PL + ++ D + Sbjct: 10 IKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSG 69 Query: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRI-YDMDKDGYISNGELFQVLKM--MVGNNLKD 126 + K F+ + F +G E R YD D D ++ LF +LK+ L Sbjct: 70 LTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLD--LTPEYLFPLLKIPPDCTTELNH 127 Query: 127 TQLQQIVDKTIINADKDGDGRISFEE 152 + T D D D +S +E Sbjct: 128 HAY-LFLQSTFDKHDLDRDCALSPDE 152 Score = 29.5 bits (65), Expect = 0.79, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 25/55 (45%), Gaps = 1/55 (1%) Query: 23 LGKRFKKLDLDNSGSLSVEEFMSLPELQQN-PLVQRVIDIFDTDGNGEVDFKEFI 76 L F K DLD +LS +E L ++ P V + T+ G + ++ F+ Sbjct: 133 LQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFL 187 >5NRK-B nrPDB Length = 68 Score = 29.9 bits (66), Expect = 0.59, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 27/57 (47%), Gaps = 5/57 (8%) Query: 100 DMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAV 156 D+D +G I+ + + ++G NLKD + + D +GD I+ +F + Sbjct: 4 DVDGNGSININDFALMRNYLLG-NLKDFPAEDDIK----AGDLNGDKSINSLDFAIM 55 >1IQ3-A nrPDB Length = 110 Score = 29.9 bits (66), Expect = 0.60, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 28/68 (41%), Gaps = 4/68 (5%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLS---VEEFMSLPELQQNPLVQRVIDIFDTDGNGEV 70 ++ + +F+ L D S +S + F + +L P + + ++ D D +G + Sbjct: 15 RITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSI-PELSYIWELSDADCDGAL 73 Query: 71 DFKEFIEG 78 EF Sbjct: 74 TLPEFCAA 81 >5X2E-A nrPDB Length = 80 Score = 29.5 bits (65), Expect = 0.66, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 22/63 (34%), Gaps = 2/63 (3%) Query: 25 KRFKKLDLDNSGSLSVEEFMSLP--ELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQF 82 F +D D + +S E +V++ +FD D G + + F + Sbjct: 5 NIFVSIDKDGTNVISYPELEQYVAENNLDPSMVEKWKQLFDPDNTGSITLETFCSKLGLK 64 Query: 83 SVK 85 + Sbjct: 65 PAE 67 Score = 29.1 bits (64), Expect = 0.87, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 24/53 (45%), Gaps = 3/53 (5%) Query: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNG 110 + D DG + + E + V++ ++ +K + +++D D G I+ Sbjct: 6 IFVSIDKDGTNVISYPELEQYVAENNLDPSMVEKWK---QLFDPDNTGSITLE 55 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 7/63 (11%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 F D D IS EL Q + NNL + +V+K D D G I+ E FC+ Sbjct: 7 FVSIDKDGTNVISYPELEQYVAE---NNLDPS----MVEKWKQLFDPDNTGSITLETFCS 59 Query: 156 VVG 158 +G Sbjct: 60 KLG 62 Score = 27.2 bits (59), Expect = 3.6, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 24/44 (54%), Gaps = 3/44 (6%) Query: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ 56 ++ D +++ + F D DN+GS+++E F S L+ ++ Sbjct: 30 NNLDPSMVEKWKQLF---DPDNTGSITLETFCSKLGLKPAEIID 70 >2D58-A nrPDB Length = 107 Score = 29.5 bits (65), Expect = 0.70, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 33/71 (46%), Gaps = 7/71 (9%) Query: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR-I 148 + + + +D++ +G I L ++L+ + G +L++++ + G G Sbjct: 32 EGFKEKYMEFDLNGNGDIDIMSLKRMLEKL-GVPKTHLELKKLIGEV-----SSGSGETF 85 Query: 149 SFEEFCAVVGG 159 S+ +F ++ G Sbjct: 86 SYPDFLRMMLG 96 Score = 29.1 bits (64), Expect = 0.88, Method: Composition-based stats. Identities = 7/64 (10%), Positives = 27/64 (42%), Gaps = 4/64 (6%) Query: 20 IKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDFKEF 75 ++ +++ + DL+ +G + + + E P ++++I + + +F Sbjct: 31 LEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDF 90 Query: 76 IEGV 79 + + Sbjct: 91 LRMM 94 >2KHN-A nrPDB Length = 121 Score = 29.1 bits (64), Expect = 0.86, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 22/59 (37%), Gaps = 7/59 (11%) Query: 104 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 G+I+ + + Q ++ + AD + DGR+ EF + + + Sbjct: 46 SGFITGDQARNFF-------FQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKL 97 >4JB3-A nrPDB Length = 228 Score = 29.1 bits (64), Expect = 0.93, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 35/97 (36%), Gaps = 4/97 (4%) Query: 49 LQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKG--DKEQKLRFAFR--IYDMDKD 104 +N Q +I D G + + + V F G D + +L + I+ ++ Sbjct: 14 GTENLYFQSMIKNIVFDFGGVIVDIDRDKAVQAFIKLGLADADTRLDKYHQTGIFQELEE 73 Query: 105 GYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINAD 141 G +S E + L + G L + +Q D Sbjct: 74 GKLSADEFRKQLGDLCGRELTMEETKQAWLGFFNEVD 110 >5MKE-A nrPDB Length = 968 Score = 29.1 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 3/50 (6%) Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 G G+++F E + KG + ++ F YD D D ++ E Q+ Sbjct: 732 GGGKLNFDELRQ---DLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQM 778 Score = 27.2 bits (59), Expect = 3.9, Method: Composition-based stats. Identities = 6/36 (16%), Positives = 11/36 (30%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ 56 + F K D D L+ E + + + Sbjct: 753 AEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKERED 788 >1NUB-A nrPDB Length = 229 Score = 29.1 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 26/64 (40%), Gaps = 8/64 (12%) Query: 92 LRFAFRIYDMDK-DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + F D DGY+S+ EL + ++ ++ + D D D I+ Sbjct: 157 VHWQFGQLDQHPIDGYLSHTELAPLRAPLI-------PMEHCTTRFFETCDLDNDKYIAL 209 Query: 151 EEFC 154 +E+ Sbjct: 210 DEWA 213 >2CXJ-A nrPDB Length = 98 Score = 28.8 bits (63), Expect = 1.1, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 105 GYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 G ++ E ++ + + LKD +D+ + D + D + F E+ ++G L Sbjct: 31 GSLNINEFKELATQQLPHLLKDVGS---LDEKMKTLDVNQDSELRFSEYWRLIGEL 83 Score = 26.4 bits (57), Expect = 6.8, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Query: 34 NSGSLSVEEFMSLPELQQNPLVQRV------IDIFDTDGNGEVDFKEFIEGVSQFSVKGD 87 GSL++ EF L Q L++ V + D + + E+ F E+ + + + + Sbjct: 29 RKGSLNINEFKELATQQLPHLLKDVGSLDEKMKTLDVNQDSELRFSEYWRLIGELAKEVR 88 Query: 88 KEQKL 92 KE+ L Sbjct: 89 KEKAL 93 >6D1W-A nrPDB Length = 740 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 3/50 (6%) Query: 66 GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 G G+++F E + KG + ++ F YD D D ++ E Q+ Sbjct: 680 GGGKLNFDELRQ---DLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQM 726 Score = 26.8 bits (58), Expect = 4.4, Method: Composition-based stats. Identities = 6/36 (16%), Positives = 11/36 (30%) Query: 21 KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQ 56 + F K D D L+ E + + + Sbjct: 701 AEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKERED 736 >2JQ6-A nrPDB Length = 139 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 19/51 (37%), Gaps = 7/51 (13%) Query: 104 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 +G I+ + +K ++ K AD D DG + EEF Sbjct: 64 NGKITGANAKK-------EMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFA 107 >1YUT-A nrPDB Length = 98 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 27/54 (50%), Gaps = 3/54 (5%) Query: 107 ISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 +S E +++ + + LKD +D+ + + D + D + F E+ ++G L Sbjct: 33 LSVNEFKELVTQQLPHLLKDVGS---LDEKMKSLDVNQDSELKFNEYWRLIGEL 83 >2KAY-A nrPDB Length = 92 Score = 28.4 bits (62), Expect = 1.5, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 26/57 (45%), Gaps = 3/57 (5%) Query: 106 YISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDI 162 +S EL +++K + + +D + + DK+ D I F+E+ + L + Sbjct: 28 TLSRKELKELIKKEL---CLGEMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCM 81 >2KFH-A nrPDB Length = 105 Score = 28.4 bits (62), Expect = 1.5, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 19/51 (37%), Gaps = 7/51 (13%) Query: 104 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 +G I+ + +K ++ K AD D DG + EEF Sbjct: 30 NGKITGANAKK-------EMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFA 73 >3VSL-A nrPDB Length = 646 Score = 28.4 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 16/29 (55%), Gaps = 2/29 (6%) Query: 16 DADEIKRLGKRFKKL--DLDNSGSLSVEE 42 EIK++ + FK D D +G +S ++ Sbjct: 537 TEKEIKQIQEGFKMAFNDKDGTGYVSFKD 565 >4TX3-A nrPDB Length = 404 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 16/112 (14%), Positives = 36/112 (32%), Gaps = 21/112 (18%) Query: 42 EFMSLPELQQNPLVQRVIDIFDTDGNGE---VDFKEFIEGVSQFSVKGDKEQKLRFAFRI 98 E + +P Q +Q D + + F + + K+ Sbjct: 160 ELIGVPRDDQAMFLQLCHRHLDASLSARKRAAAGEAFARYLVAMMARERKDP-------- 211 Query: 99 YDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 DG+I + + G+ + D +L+ + + ++ D + G I Sbjct: 212 ----GDGFIGS------IVAEHGDTITDEELRGVCVQLMLAGDDNVSGMIGL 253 >4MN0-A nrPDB Length = 208 Score = 28.0 bits (61), Expect = 2.0, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 3/48 (6%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPE 48 +GN+ + +E + RL KRF DLD+ G + ++E + P+ Sbjct: 19 VGNQWQFNVED---LHPKMLSRLYKRFDTFDLDSDGKMEMDEVLYWPD 63 >5MVF-A nrPDB Length = 523 Score = 28.0 bits (61), Expect = 2.1, Method: Composition-based stats. Identities = 32/127 (25%), Positives = 48/127 (37%), Gaps = 27/127 (21%) Query: 36 GSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFA 95 G +S EE M++P FD G F +G + + +G E++ A Sbjct: 380 GLISQEE-MNMPTQMVQG------GAFDGTTEGP-----FNQGYGEGAKEGADEEEWVVA 427 Query: 96 FRIYDMDK--------DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGR 147 D+ +G IS K MV + L ++ L +I AD D DG Sbjct: 428 KDKPVYDELFYTLSPINGKISG---VNAKKEMVTSKLPNSVLGKIWKL----ADCDCDGM 480 Query: 148 ISFEEFC 154 + EEF Sbjct: 481 LDEEEFA 487 >4U3S-B nrPDB Length = 184 Score = 28.0 bits (61), Expect = 2.3, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 24/50 (48%), Gaps = 8/50 (16%) Query: 103 KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 +DG I+ ++ ++ K G + D + Q + D + DG IS E+ Sbjct: 128 QDGAINLEDILEICKAF-GTSSTDAKYQ-------VGLDLNRDGAISLED 169 >4GFT-A nrPDB Length = 69 Score = 28.0 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 25/59 (42%), Gaps = 1/59 (1%) Query: 85 KGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKD 143 D ++L F +D + GY++ ++ +L G+ L D + ++ + D Sbjct: 2 DKDNVEELIKMFAHFDNNSTGYLTKSQMKNILTT-WGDALTDQEAIDALNAFSSEDNID 59 Score = 26.4 bits (57), Expect = 6.2, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 27/64 (42%), Gaps = 2/64 (3%) Query: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPEL-QQNPLVQRVIDIFDT-DGNGEVDFK 73 D D ++ L K F D +++G L+ + ++ Q ID + +D+K Sbjct: 2 DKDNVEELIKMFAHFDNNSTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDNIDYK 61 Query: 74 EFIE 77 F E Sbjct: 62 LFCE 65 >2JMM-A nrPDB Length = 156 Score = 27.6 bits (60), Expect = 2.8, Method: Composition-based stats. Identities = 7/12 (58%), Positives = 8/12 (66%) Query: 100 DMDKDGYISNGE 111 D D +GYIS E Sbjct: 90 DKDGNGYISAAE 101 >1DJX-A nrPDB Length = 624 Score = 27.6 bits (60), Expect = 2.9, Method: Composition-based stats. Identities = 6/72 (8%), Positives = 23/72 (31%), Gaps = 4/72 (5%) Query: 28 KKLDLDNSGSLSVEEFMSLPELQQNP----LVQRVIDIFDTDGNGEVDFKEFIEGVSQFS 83 +K D + ++ +E + +++ D ++ +E + Sbjct: 18 RKADKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQTDSLEDEEIETFYKMLT 77 Query: 84 VKGDKEQKLRFA 95 + + ++ A Sbjct: 78 QRAEIDRAFEEA 89 Score = 26.4 bits (57), Expect = 6.4, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 27/81 (33%), Gaps = 12/81 (14%) Query: 85 KGDKEQKL----RFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA 140 D+ QKL R D +KD ++ EL LK + + D K Sbjct: 2 SMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKEL-NIQVDD----GYARKIFREC 56 Query: 141 DKDGDGRISFEE---FCAVVG 158 D + EE F ++ Sbjct: 57 DHSQTDSLEDEEIETFYKMLT 77 Score = 26.1 bits (56), Expect = 7.3, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Query: 54 LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113 + + D + + +++FKE + + + +++ D + R FR D + + + E+ Sbjct: 12 WIHSCLRKADKNKDNKMNFKELKDFLKELNIQVD-DGYARKIFRECDHSQTDSLEDEEIE 70 Query: 114 QVLKMMVGNNLKDTQLQQ 131 KM+ D ++ Sbjct: 71 TFYKMLTQRAEIDRAFEE 88 >4F4Z-B nrPDB Length = 361 Score = 27.6 bits (60), Expect = 3.0, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 24/50 (48%), Gaps = 3/50 (6%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDT 64 D +E+KRL + D+ G+++ E+ +L N LV + FD Sbjct: 166 IDDEEVKRLIRELDIADVPGIGNITAEKLK---KLGINKLVDTLSIEFDK 212 >5EX6-C nrPDB Length = 434 Score = 27.2 bits (59), Expect = 3.2, Method: Composition-based stats. Identities = 16/115 (13%), Positives = 35/115 (30%), Gaps = 27/115 (23%) Query: 42 EFMSLPELQQNPLVQRVIDIFDTDGNGEVD------FKEFIEGVSQFSVKGDKEQKLRFA 95 E + +P + +Q D +G F ++ + K Sbjct: 190 ELLGVPRDDRAMFLQLCHRHLDASLSGRRRAAAGEAFSRYLVTMVARERKDP-------- 241 Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 DG I ++ G+ + D +L+ + + ++ D + G I Sbjct: 242 -------GDGLIG------MVVAEHGDTVTDEELRGVCVQMMLAGDDNISGMIGL 283 >4PCW-A nrPDB Length = 94 Score = 27.2 bits (59), Expect = 3.3, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 124 LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160 LK+ +VD + + D D + +I F EF +V L Sbjct: 47 LKNPDDPDMVDVFMDHLDIDHNKKIDFTEFLLMVFKL 83 >6IBE-A nrPDB Length = 286 Score = 27.2 bits (59), Expect = 3.3, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 31/81 (38%), Gaps = 2/81 (2%) Query: 17 ADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 76 +++I R + D SG L F++L L VQ + +D D G EF Sbjct: 93 SEDITRYYLCLQLRDDIVSGRLPCS-FVTLALLGSY-TVQSELGDYDPDECGSDYISEFR 150 Query: 77 EGVSQFSVKGDKEQKLRFAFR 97 + DK +L + R Sbjct: 151 FAPNHTKELEDKVIELHKSHR 171 >1PHK-A nrPDB Length = 298 Score = 27.2 bits (59), Expect = 3.4, Method: Composition-based stats. Identities = 16/108 (14%), Positives = 44/108 (40%), Gaps = 31/108 (28%) Query: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFK 73 F A+E++ L + +++E L ++ +P + ++ D ++T+ Sbjct: 57 SFSAEEVQELREA------------TLKEVDILRKVSGHPNIIQLKDTYETN-------- 96 Query: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYD-MDKDGYISNGELFQVLKMMV 120 F V KG+ ++D + + +S E ++++ ++ Sbjct: 97 TFFFLVFDLMKKGE----------LFDYLTEKVTLSEKETRKIMRALL 134 >2UVV-A nrPDB Length = 358 Score = 27.2 bits (59), Expect = 3.9, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 24/50 (48%), Gaps = 3/50 (6%) Query: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDT 64 D +E+KRL + D+ G+++ E+ +L N LV + FD Sbjct: 172 IDDEEVKRLIRELDIADVPGIGNITAEKLK---KLGINKLVDTLSIEFDK 218 >4CJ1-A nrPDB Length = 625 Score = 26.8 bits (58), Expect = 4.2, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 24/54 (44%), Gaps = 13/54 (24%) Query: 100 DMDKDGYISNGEL----FQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRIS 149 D++ DG +++ +L VLK + + NAD + DGR++ Sbjct: 561 DVNDDGKVNSTDLTLLKRYVLKAVSTLPSSKAE---------KNADVNRDGRVN 605 >2QPT-A nrPDB Length = 550 Score = 26.4 bits (57), Expect = 5.8, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 7/51 (13%) Query: 104 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154 DG +S + MVG L ++ L +I +D D DG + EEF Sbjct: 471 DGKLSGS---KAKTWMVGTKLPNSVLGRIWKL----SDVDRDGMLDDEEFA 514 >1NKS-A nrPDB Length = 194 Score = 26.4 bits (57), Expect = 6.3, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 46 LPELQQNPLVQRVIDIFDTDG--NGEVDFKEFIEGVSQFSVKGDKEQKLRF 94 +P + ++ ++ +V +I D G N +++ +F+ + ++R Sbjct: 9 IPGVGKSTVLAKVKEILDNQGINNKIINYGDFMLATALKLGYAKDRDEMRK 59 >4WI0-B nrPDB Length = 156 Score = 26.4 bits (57), Expect = 6.4, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 24/50 (48%), Gaps = 8/50 (16%) Query: 103 KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 +DG I+ ++ ++ K ++ D + Q + D + DG IS E+ Sbjct: 100 QDGAINLEDILEICKAFNTSS-TDAKYQ-------VGLDLNRDGAISLED 141 >4N9F-U nrPDB Length = 311 Score = 26.4 bits (57), Expect = 6.6, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 29/72 (40%), Gaps = 1/72 (1%) Query: 35 SGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEV-DFKEFIEGVSQFSVKGDKEQKLR 93 L EE +L L+ V + + N V FKE I Q +K ++ +KL Sbjct: 225 DAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLH 284 Query: 94 FAFRIYDMDKDG 105 F + D +G Sbjct: 285 LMFSLMDKVPNG 296 >1FI6-A nrPDB Length = 92 Score = 26.4 bits (57), Expect = 6.6, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 26/60 (43%), Gaps = 7/60 (11%) Query: 96 FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 F+ D +G+I + L+ + + ++ +D D DG ++ +EFCA Sbjct: 15 FKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWEL-------SDFDKDGALTLDEFCA 67 >2Y3N-B nrPDB Length = 71 Score = 26.4 bits (57), Expect = 6.9, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 25/53 (47%), Gaps = 8/53 (15%) Query: 100 DMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEE 152 D++ DG I+ ++ +L G + + + + AD + DG I+ ++ Sbjct: 8 DLNGDGVINMADVM-ILAQSFGKAIGNPGVNE-------KADLNNDGVINSDD 52 >1SRA-A nrPDB Length = 151 Score = 26.1 bits (56), Expect = 7.1, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 26/64 (40%), Gaps = 8/64 (12%) Query: 92 LRFAFRIYDMDK-DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISF 150 + + F D DGY+S+ EL + ++ ++ + D D D I+ Sbjct: 79 VHWQFGQLDQHPIDGYLSHTELAPLRAPLI-------PMEHCTTRFFETCDLDNDKYIAL 131 Query: 151 EEFC 154 +E+ Sbjct: 132 DEWA 135 >4AQI-A nrPDB Length = 109 Score = 26.1 bits (56), Expect = 7.6, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 2/60 (3%) Query: 103 KDGYISNGELFQVLKMMVGNNLKDTQLQQI--VDKTIINADKDGDGRISFEEFCAVVGGL 160 +DG I L ++K N L + I + DK+ D +I F EF +++G + Sbjct: 28 RDGKIEKPSLLTMMKENFPNFLSACDKKGIHYLATVFEKKDKNEDKKIDFSEFLSLLGDI 87 >4JGH-D nrPDB Length = 378 Score = 26.1 bits (56), Expect = 7.9, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 40/114 (35%), Gaps = 11/114 (9%) Query: 35 SGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEV-DFKEFIEGVSQFSVKGDKEQKLR 93 L EE +L L+ V + + N V FKE I Q +K ++ +KL Sbjct: 226 DAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLH 285 Query: 94 FAFRIYDMDKDG----------YISNGELFQVLKMMVGNNLKDTQLQQIVDKTI 137 F + D +G +I + L ++ + ++ +D Sbjct: 286 LMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYREQLDTLF 339 >1EUC-B nrPDB Length = 396 Score = 26.1 bits (56), Expect = 8.1, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 37/96 (38%), Gaps = 7/96 (7%) Query: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNG 68 L + AD+IK+L F K+D + V F PE Q ++ + D N Sbjct: 178 LGPLQNQAADQIKKLYNLFLKIDAT---QVEVNPFGETPEGQVVCFDAKI----NFDDNA 230 Query: 69 EVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKD 104 E K+ + + + + ++ + +D + Sbjct: 231 EFRQKDIFAMDDKSENEPIENEAAKYDLKYIGLDGN 266 >3ICE-A nrPDB Length = 422 Score = 26.1 bits (56), Expect = 8.2, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 29/65 (44%), Gaps = 5/65 (7%) Query: 24 GKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFS 83 + F +D + SG+ E + ELQ+ +++++I GE+D EF+ + Sbjct: 355 KRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPM-----GEIDAMEFLINKLAMT 409 Query: 84 VKGDK 88 D Sbjct: 410 KTNDD 414 >5J6D-A nrPDB Length = 307 Score = 26.1 bits (56), Expect = 8.3, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 15/32 (46%), Gaps = 1/32 (3%) Query: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDL 32 M + P+ F +EIK G F++L+ Sbjct: 52 MNYKHGDPIPKV-EFTEEEIKTWGTVFQELNK 82 >3OZ6-A nrPDB Length = 388 Score = 26.1 bits (56), Expect = 8.6, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 34/83 (40%), Gaps = 3/83 (3%) Query: 19 EIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF--DTDGNGEVDFKEFI 76 E+ + K F + E M L EL + + ++++ D D + + F +++ Sbjct: 35 EVVAVKKIFDAFQNSTDAQRTFREIMILTELSGHENIVNLLNVLRADNDRDVYLVF-DYM 93 Query: 77 EGVSQFSVKGDKEQKLRFAFRIY 99 E ++ + + + + +Y Sbjct: 94 ETDLHAVIRANILEPVHKQYVVY 116 >6EM8-A nrPDB Length = 818 Score = 26.1 bits (56), Expect = 9.2, Method: Composition-based stats. Identities = 12/85 (14%), Positives = 37/85 (43%), Gaps = 6/85 (7%) Query: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGY---ISNGE 111 +++ I+ + + V +EF + + E++ A + ++G +S + Sbjct: 416 IEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNAQNGMSTSLSEED 475 Query: 112 LFQVLKMMVGNNLK---DTQLQQIV 133 + +V+ G L +T+ ++++ Sbjct: 476 IAEVIAGWTGIPLTKINETESEKLL 500 >1OHZ-B nrPDB Length = 60 Score = 26.1 bits (56), Expect = 9.2, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 19/46 (41%), Gaps = 2/46 (4%) Query: 31 DLDNSGSLSVEEFMSLPE--LQQNPLVQRVIDIFDTDGNGEVDFKE 74 D++ G+++ + L L+ L D D NG ++ + Sbjct: 3 DVNGDGTINSTDLTMLKRSVLRAITLTDDAKARADVDKNGSINSTD 48 >6G18-t nrPDB Length = 475 Score = 25.7 bits (55), Expect = 9.7, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 34/82 (41%), Gaps = 1/82 (1%) Query: 31 DLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQ 90 D D++G LS E+ MS+P + + + + ++ + + ++ Sbjct: 203 DYDSAGLLSDEDCMSVPGKTHRAIADHLFWS-EETKSRFTEYSMTSSVMRRNEQLTLHDE 261 Query: 91 KLRFAFRIYDMDKDGYISNGEL 112 + + YD D+ G + N EL Sbjct: 262 RFEKFYEQYDDDEIGALDNAEL 283 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.145 0.389 Lambda K H 0.267 0.0446 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,346,755 Number of Sequences: 36641 Number of extensions: 297422 Number of successful extensions: 4698 Number of sequences better than 10.0: 363 Number of HSP's better than 10.0 without gapping: 497 Number of HSP's successfully gapped in prelim test: 118 Number of HSP's that attempted gapping in prelim test: 1284 Number of HSP's gapped (non-prelim): 1558 length of query: 170 length of database: 10,336,785 effective HSP length: 90 effective length of query: 80 effective length of database: 7,039,095 effective search space: 563127600 effective search space used: 563127600 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 56 (26.1 bits)