BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P60843 (406 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3EIQ-A nrPDB 840 0.0 2HYI-C nrPDB 561 e-160 2VSX-A nrPDB 502 e-142 5ZBZ-A nrPDB 454 e-128 3BOR-A nrPDB 422 e-118 4BRW-A nrPDB 311 3e-85 5ANR-B nrPDB 284 5e-77 1QVA-A nrPDB 282 2e-76 6B4I-E nrPDB 280 6e-76 5IVL-B nrPDB 280 1e-75 3PEW-A nrPDB 275 2e-74 1XTI-A nrPDB 261 3e-70 3FHO-A nrPDB 258 3e-69 5SUQ-A nrPDB 251 3e-67 5SUP-A nrPDB 251 3e-67 1HV8-A nrPDB 249 2e-66 4NHO-A nrPDB 207 6e-54 3JCR-F nrPDB 203 1e-52 2I4I-A nrPDB 201 5e-52 6CZ5-A nrPDB 200 8e-52 5DTU-A nrPDB 196 2e-50 4D25-A nrPDB 193 9e-50 2DB3-A nrPDB 193 1e-49 4KBG-A nrPDB 190 1e-48 4W7S-A nrPDB 179 3e-45 5ZWN-y nrPDB 178 3e-45 6CB1-p nrPDB 177 1e-44 2Z0M-A nrPDB 170 8e-43 4LJY-A nrPDB 164 8e-41 2OXC-A nrPDB 160 1e-39 3I62-A nrPDB 158 4e-39 3SQW-A nrPDB 158 4e-39 5GJU-A nrPDB 155 3e-38 1VEC-A nrPDB 150 8e-37 1T6N-A nrPDB 148 4e-36 6AIC-A nrPDB 146 2e-35 3FHC-B nrPDB 140 8e-34 2KBE-A nrPDB 139 2e-33 3FMO-B nrPDB 139 2e-33 1WRB-A nrPDB 124 9e-29 2GXQ-A nrPDB 123 2e-28 1Q0U-A nrPDB 121 5e-28 3BER-A nrPDB 121 5e-28 5H1Y-A nrPDB 114 8e-26 5GVS-A nrPDB 113 1e-25 3LY5-A nrPDB 110 1e-24 4PX9-A nrPDB 106 2e-23 3FE2-A nrPDB 105 3e-23 2PL3-A nrPDB 101 6e-22 3IUY-A nrPDB 96 4e-20 3DKP-A nrPDB 84 1e-16 6CRM-A nrPDB 63 2e-10 1OYY-A nrPDB 58 9e-09 5LST-A nrPDB 55 4e-08 5V9X-A nrPDB 54 1e-07 4GL2-A nrPDB 48 7e-06 4Q48-A nrPDB 48 7e-06 1GM5-A nrPDB 47 1e-05 4CDG-A nrPDB 47 1e-05 5AGA-A nrPDB 47 2e-05 6G19-A nrPDB 46 3e-05 2WWY-A nrPDB 46 3e-05 5LBA-B nrPDB 44 1e-04 5LB8-A nrPDB 44 1e-04 5JCF-A nrPDB 43 3e-04 1D9Z-A nrPDB 43 3e-04 1WP9-A nrPDB 43 3e-04 2NMV-A nrPDB 42 4e-04 4A2W-A nrPDB 41 8e-04 4A2Q-A nrPDB 41 8e-04 5TNU-A nrPDB 41 9e-04 4A36-A nrPDB 41 0.001 1C4O-A nrPDB 40 0.003 2FWR-A nrPDB 39 0.004 4ON9-A nrPDB 39 0.006 3TBK-A nrPDB 38 0.007 4BPB-A nrPDB 37 0.011 5JBJ-A nrPDB 36 0.026 6QKC-A nrPDB 33 0.18 2ZJ8-A nrPDB 33 0.20 3TF5-A nrPDB 32 0.43 6BOG-A nrPDB 32 0.73 2VA8-A nrPDB 31 0.78 3AX1-A nrPDB 31 0.84 6BYQ-A nrPDB 31 1.1 5V8F-E nrPDB 31 1.1 6DCR-A nrPDB 31 1.3 5IDF-B nrPDB 30 1.9 4IE5-A nrPDB 30 2.0 5JXT-B nrPDB 29 3.7 4WTS-A nrPDB 29 4.8 4NL8-A nrPDB 28 5.4 5JXR-A nrPDB 28 5.8 6BQZ-A nrPDB 28 5.8 6FNP-B nrPDB 28 6.6 4U1Y-A nrPDB 28 7.1 >3EIQ-A nrPDB Length = 414 Score = 840 bits (2170), Expect = 0.0, Method: Compositional matrix adjust. Identities = 406/406 (100%), Positives = 406/406 (100%) Query: 1 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 60 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ Sbjct: 9 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 68 Query: 61 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 120 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV Sbjct: 69 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 128 Query: 121 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 180 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV Sbjct: 129 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 188 Query: 181 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE Sbjct: 189 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 248 Query: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 300 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS Sbjct: 249 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 308 Query: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI Sbjct: 309 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 368 Query: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI Sbjct: 369 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 414 >2HYI-C nrPDB Length = 413 Score = 561 bits (1446), Expect = e-160, Method: Compositional matrix adjust. Identities = 271/406 (66%), Positives = 328/406 (80%), Gaps = 1/406 (0%) Query: 1 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 60 M+ S +R R + M S ++ +FD M L E LLRGIYAYGFEKPSAIQQ Sbjct: 7 MATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQ 66 Query: 61 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 120 RAI IKG DVIAQ+QSGTGKTATF+IS+LQ +++ ++ TQAL+LAPTRELA QIQK + Sbjct: 67 RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126 Query: 121 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 180 +ALGDYM CHACIGGTNV +++KL H++ GTPGRVFDM+ RR L + IKM V Sbjct: 127 LALGDYMNVQCHACIGGTNVGEDIRKLDY-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLV 185 Query: 181 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240 LDEADEML++GFK+QIYD+++ L TQVVL+SAT+P ++LE+T KFM DPIRILVK++E Sbjct: 186 LDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDE 245 Query: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 300 LTLEGI+QF++ VEREEWK DTLCDLY+TLTITQAVIF NT+RKVDWLTEKM +FTVS Sbjct: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVS 305 Query: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360 +MHGDM QKER+ IM+EFRSG+SRVLI+TD+ ARG+DV QVSL+INYDLP NRE YIHRI Sbjct: 306 SMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI 365 Query: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406 GR GR+GRKGVAIN V +D R LRDIE +Y+T I+EMP+NVADLI Sbjct: 366 GRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411 >2VSX-A nrPDB Length = 395 Score = 502 bits (1292), Expect = e-142, Method: Compositional matrix adjust. Identities = 257/387 (66%), Positives = 317/387 (81%), Gaps = 2/387 (0%) Query: 20 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG 79 E I++N++++V FDDM L E+LLRG++ YGFE+PSAIQQRAI+P I+G+DV+AQAQSG Sbjct: 10 ESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSG 69 Query: 80 TGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 139 TGKT TF+I+ LQ+I+ +KA QAL+LAPTRELA QIQKVVMAL +M HACIGGT+ Sbjct: 70 TGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTS 129 Query: 140 VRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDI 199 + + L+ I+VGTPGRVFD + RR IKMF+LDEADEMLS GFK+QIY I Sbjct: 130 FVEDAEGLR--DAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQI 187 Query: 200 FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWK 259 F L TQVVLLSATMP+DVLEVT KFMR+P+RILVKK+ELTLEGI+QFY+NVE EE+K Sbjct: 188 FTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYK 247 Query: 260 LDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFR 319 + L DLY+++++TQAVIF NTRRKV+ LT K+ FTVSA++ D+ Q+ERD IM+EFR Sbjct: 248 YECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFR 307 Query: 320 SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE 379 SGSSR+LI+TDLLARGIDVQQVSLVINYDLP N+ENYIHRIGRGGRFGRKGVAIN VT E Sbjct: 308 SGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNE 367 Query: 380 DKRTLRDIETFYNTSIEEMPLNVADLI 406 D +R++E FY+T IEE+P ++A L+ Sbjct: 368 DVGAMRELEKFYSTQIEELPSDIATLL 394 >5ZBZ-A nrPDB Length = 220 Score = 454 bits (1168), Expect = e-128, Method: Compositional matrix adjust. Identities = 219/219 (100%), Positives = 219/219 (100%) Query: 20 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG 79 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG Sbjct: 2 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG 61 Query: 80 TGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 139 TGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN Sbjct: 62 TGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 121 Query: 140 VRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDI 199 VRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDI Sbjct: 122 VRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDI 181 Query: 200 FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK 238 FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK Sbjct: 182 FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK 220 >3BOR-A nrPDB Length = 237 Score = 422 bits (1085), Expect = e-118, Method: Compositional matrix adjust. Identities = 198/219 (90%), Positives = 213/219 (97%) Query: 21 GVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGT 80 GVIESNWNEIVD+FDDMNL ESLLRGIYAYGFEKPSAIQQRAI+PCIKGYDVIAQAQSGT Sbjct: 19 GVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGT 78 Query: 81 GKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNV 140 GKTATFAISILQQ+E++ K TQALVLAPTRELAQQIQKV++ALGDYMGA+CHACIGGTNV Sbjct: 79 GKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNV 138 Query: 141 RAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIF 200 R E+QKLQ EAPHI+VGTPGRVFDMLNRRYLSPK+IKMFVLDEADEMLSRGFKDQIY+IF Sbjct: 139 RNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIF 198 Query: 201 QKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKE 239 QKLN++ QVVLLSATMP+DVLEVTKKFMRDPIRILVKKE Sbjct: 199 QKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE 237 >4BRW-A nrPDB Length = 377 Score = 311 bits (798), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 165/371 (44%), Positives = 225/371 (60%), Gaps = 3/371 (0%) Query: 32 DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL 91 ++F+D L LL GI+ GFEKPS IQ+ AI I G D++A+A++GTGKTA F I L Sbjct: 1 NTFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTL 60 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEA 151 ++++ L QAL++ PTRELA Q +VV LG + G SC GGTN+R ++ +L E Sbjct: 61 EKVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHCGISCMVTTGGTNLRDDILRLN-ET 119 Query: 152 PHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL 211 HI+VGTPGRV D+ +R+ +F++DEAD+MLSR FK I I L Q +L Sbjct: 120 VHILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLPPTHQSLL 179 Query: 212 LSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLT 271 SAT P V E K + P I + EELTL+GI Q+Y VE E KL L L+ L Sbjct: 180 FSATFPLTVDEFMDKHLHKPYEINLM-EELTLKGITQYYAFVE-ERQKLHCLNTLFSKLQ 237 Query: 272 ITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDL 331 I QA+IF N+ +V+ L +K+ ++ H M Q+ER+ + EFR G R L+ +DL Sbjct: 238 INQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRTLVCSDL 297 Query: 332 LARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFY 391 L RGID+Q V++VIN+D P E Y+HRIGR GRFG G+AIN++ D+ L IE Sbjct: 298 LTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINWNDRFNLYKIEQEL 357 Query: 392 NTSIEEMPLNV 402 T I +P + Sbjct: 358 GTEIAAIPATI 368 >5ANR-B nrPDB Length = 378 Score = 284 bits (726), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 144/372 (38%), Positives = 232/372 (62%), Gaps = 4/372 (1%) Query: 32 DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL 91 + F+D L LL GI+ G+EKPS IQ+ +I + G D++A+A++GTGK+ + I +L Sbjct: 5 NEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL 64 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMG-ASCHACIGGTNVRAEVQKLQME 150 ++++L QA+V+ PTRELA Q+ ++ + + +MG A A GGTN+R ++ +L + Sbjct: 65 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLD-D 123 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV 210 H+++ TPGR+ D++ + +++M VLDEAD++LS+ F + DI L N Q++ Sbjct: 124 TVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQIL 183 Query: 211 LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 270 L SAT P V + ++ P I + EELTL+G+ Q+Y V E K+ L L+ L Sbjct: 184 LYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHCLNTLFSRL 241 Query: 271 TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330 I Q++IF N+ ++V+ L +K+ ++ +H M Q+ R+ + +FR+G R L+ TD Sbjct: 242 QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 301 Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETF 390 L RGID+Q V++VIN+D P E Y+HRIGR GRFG G+AIN++T +D+ L+ IE Sbjct: 302 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 361 Query: 391 YNTSIEEMPLNV 402 T I+ +P N+ Sbjct: 362 LGTEIKPIPSNI 373 >1QVA-A nrPDB Length = 223 Score = 282 bits (721), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 139/217 (64%), Positives = 169/217 (77%), Gaps = 2/217 (0%) Query: 20 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG 79 E I++N+ ++V FDDM L E LLRG++ YGFE+PSAIQQRAI+P I+G+DV+AQAQSG Sbjct: 9 ESQIQTNYQKVVYKFDDMELDEQLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSG 68 Query: 80 TGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 139 TGKT TF+I+ LQ+I+ +KA QAL+LAPTRELA QIQKVVMAL +M HACIGGT+ Sbjct: 69 TGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTS 128 Query: 140 VRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDI 199 + + L+ I+VGTPGRVFD + RR IKMF+LDEADEMLS GFK+QIY I Sbjct: 129 FVEDAEGLR--DAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQI 186 Query: 200 FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILV 236 F L TQVVLLSATMP+DVLEVT KFMR+P+RILV Sbjct: 187 FTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILV 223 >6B4I-E nrPDB Length = 430 Score = 280 bits (717), Expect = 6e-76, Method: Compositional matrix adjust. Identities = 155/380 (40%), Positives = 234/380 (61%), Gaps = 16/380 (4%) Query: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCI---KGYDVIAQAQSGTGKTATFA 87 V SF+++ L LL+G+YA GF +PS IQ+ A LP + ++IAQ+QSGTGKTA F Sbjct: 42 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENA-LPLMLAEPPQNLIAQSQSGTGKTAAFV 100 Query: 88 ISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKL 147 +++L Q+E K Q L L+PT ELA Q KV+ +G + A N QK+ Sbjct: 101 LAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKI 160 Query: 148 QMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEML-SRGFKDQIYDIFQKLNS 205 + I++GTPG V D ++ +++ PK IK+FVLDEAD M+ ++G +DQ I + L Sbjct: 161 ---SEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPR 217 Query: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265 N Q++L SAT V + +K + DP I +K+EE TL+ I+Q+Y+ + K LC+ Sbjct: 218 NCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCN 277 Query: 266 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRV 325 LY +TI QA+IF +TR+ WL ++ V+ + G+M ++R ++ FR G +V Sbjct: 278 LYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKV 337 Query: 326 LITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINMV-TE 378 L+TT++ ARGIDV+QVS+VIN+DLP ++ E Y+HRIGR GRFG++G+A+NMV ++ Sbjct: 338 LVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSK 397 Query: 379 EDKRTLRDIETFYNTSIEEM 398 L I+ +N IE + Sbjct: 398 HSMNILNRIQEHFNKKIERL 417 >5IVL-B nrPDB Length = 429 Score = 280 bits (715), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 140/366 (38%), Positives = 226/366 (61%), Gaps = 2/366 (0%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92 +F ++ LS+ +++ I GFE+ + IQ + I ++ DVI QAQ+GTGKTA F I I++ Sbjct: 3 TFQELGLSQEVMKAIERMGFEETTPIQAKTIPLSLQNKDVIGQAQTGTGKTAAFGIPIVE 62 Query: 93 QIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAP 152 ++++ A QALV+APTRELA Q+ + + +G GG ++ +++ L+ + P Sbjct: 63 KVDVKNGAIQALVVAPTRELAIQVSEELYKIGAVKRVRVLPIYGGQDIERQIRALK-KHP 121 Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLL 212 H+IVGTPGR+ D +NR L +++ VLDEADEML+ GF + I I + + Q +L Sbjct: 122 HVIVGTPGRIIDHINRGTLRLEHVHTVVLDEADEMLNMGFIEDIEAILSHVPAERQTLLF 181 Query: 213 SATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTI 272 SATMP + + ++FM +P + VK +E+T+ I+Q+Y+ V E+ K D L L + Sbjct: 182 SATMPDPIRRIAERFMNEPELVKVKAKEMTVPNIQQYYLEV-HEKKKFDILTRLLDIQAP 240 Query: 273 TQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLL 332 A++F T+R+VD L E ++ R + +HGD+ Q +R ++R+F+ G+ +L+ TD+ Sbjct: 241 ELAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLSQAKRLSVLRKFKEGAIEILVATDVA 300 Query: 333 ARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYN 392 ARG+D+ V+ V N+D+P + E+Y+HRIGR GR G+ GVA+ VT + L IE Sbjct: 301 ARGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGKTGVAMTFVTPREIGQLHHIERTTK 360 Query: 393 TSIEEM 398 +E M Sbjct: 361 RKMERM 366 >3PEW-A nrPDB Length = 395 Score = 275 bits (703), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 148/358 (41%), Positives = 229/358 (63%), Gaps = 16/358 (4%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCI---KGYDVIAQAQSGTGKTATFAIS 89 SFD++ L+ LL+GIYA F+KPS IQ+RA LP + ++IAQ+QSGTGKTA F+++ Sbjct: 6 SFDELGLAPELLKGIYAMKFQKPSKIQERA-LPLLLHNPPRNMIAQSQSGTGKTAAFSLT 64 Query: 90 ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQM 149 +L ++ + + QA+ LAP+RELA+Q +VV +G + + + + +K + Sbjct: 65 MLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDS-----FEKNKQ 119 Query: 150 EAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEML-SRGFKDQIYDIFQKLNSNTQ 208 +IVGTPG V D++ R+ + + IK+FVLDEAD ML +G DQ + + L +TQ Sbjct: 120 INAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQ 179 Query: 209 VVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYE 268 +VL SAT V + KK + + + ++ E+ ++ I+Q Y++ + E K D L +LY Sbjct: 180 LVLFSATFADAVRQYAKKIVPNANTLELQTNEVNVDAIKQLYMDCKNEADKFDVLTELYG 239 Query: 269 TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328 +TI ++IF+ T++ + L K+ + VS +HGD+ +ERD ++ +FR G S+VLIT Sbjct: 240 VMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLIT 299 Query: 329 TDLLARGIDVQQVSLVINYDLPT------NRENYIHRIGRGGRFGRKGVAINMVTEED 380 T++LARGID+ VS+V+NYDLPT + YIHRIGR GRFGRKGVAI+ V +++ Sbjct: 300 TNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAISFVHDKN 357 >1XTI-A nrPDB Length = 391 Score = 261 bits (668), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 139/370 (37%), Positives = 217/370 (58%), Gaps = 5/370 (1%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F D L LLR I GFE PS +Q I I G DV+ QA+SG GKTA F ++ LQQ Sbjct: 10 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 69 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAP 152 +E LV+ TRELA QI K YM GG +++ + + L+ P Sbjct: 70 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 129 Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQVVL 211 HI+VGTPGR+ + + L+ K+IK F+LDE D+ML + + + +IF+ QV++ Sbjct: 130 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 189 Query: 212 LSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVEREEWKLDTLCDLYETL 270 SAT+ ++ V +KFM+DP+ I V E +LTL G++Q+Y+ ++ E K L DL + L Sbjct: 190 FSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVL 248 Query: 271 TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330 Q VIF+ + ++ L + + ++F A+H M Q+ER ++F+ R+L+ T+ Sbjct: 249 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 308 Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE-DKRTLRDIET 389 L RG+D+++V++ NYD+P + + Y+HR+ R GRFG KG+AI V++E D + L D++ Sbjct: 309 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 368 Query: 390 FYNTSIEEMP 399 + +I E+P Sbjct: 369 RFEVNISELP 378 >3FHO-A nrPDB Length = 508 Score = 258 bits (659), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 146/355 (41%), Positives = 219/355 (61%), Gaps = 21/355 (5%) Query: 58 IQQRAILPCI---KGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQ 114 IQ++A LP + ++I Q+QSGTGKTA FA+++L +++ + QA+ LAP+RELA+ Sbjct: 145 IQEKA-LPLLLSNPPRNMIGQSQSGTGKTAAFALTMLSRVDASVPKPQAICLAPSRELAR 203 Query: 115 QIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPK 174 QI VV +G Y G ++ V K I++GTPG V D++ RR L + Sbjct: 204 QIMDVVTEMGKY--TEVKTAFG---IKDSVPKGAKIDAQIVIGTPGTVMDLMKRRQLDAR 258 Query: 175 YIKMFVLDEADEML-SRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIR 233 IK+FVLDEAD ML +G DQ I L NTQ+VL SAT V + ++F + Sbjct: 259 DIKVFVLDEADNMLDQQGLGDQSMRIKHLLPRNTQIVLFSATFSERVEKYAERFAPNANE 318 Query: 234 ILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH 293 I +K EEL++EGI+Q Y++ + EE K + L +LY LTI Q++IF + + + +M Sbjct: 319 IRLKTEELSVEGIKQLYMDCQSEEHKYNVLVELYGLLTIGQSIIFCKKKDTAEEIARRMT 378 Query: 294 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 353 A TV+ + G+++ +RD IM FR G+S+VL+TT+++ARGIDV QV+LV+NYD+P ++ Sbjct: 379 ADGHTVACLTGNLEGAQRDAIMDSFRVGTSKVLVTTNVIARGIDVSQVNLVVNYDMPLDQ 438 Query: 354 ------ENYIHRIGRGGRFGRKGVAINMVTEEDKRT---LRDIETFYNTSIEEMP 399 + Y+HRIGR GRFGR GV+IN V DK++ + I+ ++ I +P Sbjct: 439 AGRPDPQTYLHRIGRTGRFGRVGVSINFV--HDKKSWEEMNAIQEYFQRPITRVP 491 >5SUQ-A nrPDB Length = 446 Score = 251 bits (642), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 137/372 (36%), Positives = 217/372 (58%), Gaps = 7/372 (1%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F D L L R I GFE PS +QQ I I G DV+ QA+SG GKTA F +S LQQ Sbjct: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACI-GGTNVR--AEVQKLQME 150 ++ +V+ RELA QI+ + YM A GGT + AE+ K + Sbjct: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQV 209 APHI+V TPGR+ ++ +Y+ ++K FV+DE D++L + + +IF+ + QV Sbjct: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 Query: 210 VLLSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVEREEWKLDTLCDLYE 268 ++ SAT+ ++ + ++F+++P+ I V E +LTL G++Q+YI +E E K L L + Sbjct: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEERE-KNRKLAQLLD 302 Query: 269 TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328 L Q +IF+ + + + LT+ ++A +F +HG M Q+ER + F+ R+ ++ Sbjct: 303 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 362 Query: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV-TEEDKRTLRDI 387 TD+ RGID+++++L INYDL + Y+HR+GR GRFG KG+AI+ V ++ED+ L I Sbjct: 363 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 422 Query: 388 ETFYNTSIEEMP 399 + ++ I E P Sbjct: 423 QERFDVKIAEFP 434 >5SUP-A nrPDB Length = 390 Score = 251 bits (642), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 137/372 (36%), Positives = 217/372 (58%), Gaps = 7/372 (1%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F D L L R I GFE PS +QQ I I G DV+ QA+SG GKTA F +S LQQ Sbjct: 8 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 67 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACI-GGTNVR--AEVQKLQME 150 ++ +V+ RELA QI+ + YM A GGT + AE+ K + Sbjct: 68 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 127 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQV 209 APHI+V TPGR+ ++ +Y+ ++K FV+DE D++L + + +IF+ + QV Sbjct: 128 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 187 Query: 210 VLLSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVEREEWKLDTLCDLYE 268 ++ SAT+ ++ + ++F+++P+ I V E +LTL G++Q+YI +E E K L L + Sbjct: 188 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEERE-KNRKLAQLLD 246 Query: 269 TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328 L Q +IF+ + + + LT+ ++A +F +HG M Q+ER + F+ R+ ++ Sbjct: 247 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 306 Query: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV-TEEDKRTLRDI 387 TD+ RGID+++++L INYDL + Y+HR+GR GRFG KG+AI+ V ++ED+ L I Sbjct: 307 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 366 Query: 388 ETFYNTSIEEMP 399 + ++ I E P Sbjct: 367 QERFDVKIAEFP 378 >1HV8-A nrPDB Length = 367 Score = 249 bits (635), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 136/369 (36%), Positives = 217/369 (58%), Gaps = 10/369 (2%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAI-LPCIKGYDVIAQAQSGTGKTATFAISIL 91 +F+++NLS+++L I GFEKP+ IQ + I L Y+++AQA++G+GKTA+FAI ++ Sbjct: 7 NFNELNLSDNILNAIRNKGFEKPTDIQMKVIPLFLNDEYNIVAQARTGSGKTASFAIPLI 66 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEA 151 + + + +A++L PTRELA Q+ + +L GG + +++ L+ Sbjct: 67 ELVNEN-NGIEAIILTPTRELAIQVADEIESLKGNKNLKIAKIYGGKAIYPQIKALK--N 123 Query: 152 PHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL 211 +I+VGTPGR+ D +NR L+ K +K F+LDEADEML+ GF + I N + +++L Sbjct: 124 ANIVVGTPGRILDHINRGTLNLKNVKYFILDEADEMLNMGFIKDVEKILNACNKDKRILL 183 Query: 212 LSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLT 271 SATMP ++L + KK+M D I K I Q Y+ V E + + LC L + Sbjct: 184 FSATMPREILNLAKKYMGDYSFIKAKINA----NIEQSYVEVNENE-RFEALCRLLKNKE 238 Query: 272 ITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDL 331 ++F T+R L + F A+HGD+ Q +R+ ++R F+ R+LI TD+ Sbjct: 239 FY-GLVFCKTKRDTKELASMLRDIGFKAGAIHGDLSQSQREKVIRLFKQKKIRILIATDV 297 Query: 332 LARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFY 391 ++RGIDV ++ VINY LP N E+Y+HRIGR GR G+KG AI+++ + + LR IE Sbjct: 298 MSRGIDVNDLNCVINYHLPQNPESYMHRIGRTGRAGKKGKAISIINRREYKKLRYIERAM 357 Query: 392 NTSIEEMPL 400 I+++ Sbjct: 358 KLKIKKLKF 366 >4NHO-A nrPDB Length = 488 Score = 207 bits (527), Expect = 6e-54, Method: Compositional matrix adjust. Identities = 125/411 (30%), Positives = 210/411 (51%), Gaps = 40/411 (9%) Query: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90 + S+ D +L +L I G+++P+ IQ++AI ++ D+I A++G+GKTA F I + Sbjct: 58 IRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPL 117 Query: 91 L---------QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVR 141 L +IE + A++LAPTRELAQQI++ + G +G A IGG + Sbjct: 118 LVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISRE 177 Query: 142 AEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQ 201 + +L+M I++ TPGR+ D+L RYL VLDEAD M+ GF+ + I + Sbjct: 178 DQGFRLRMGC-EIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILE 236 Query: 202 KL--------------------------NSNTQVVLLSATMPSDVLEVTKKFMRDPIRIL 235 + + Q V+ +ATMP V + + ++R P + Sbjct: 237 HMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVY 296 Query: 236 VKKEELTLEGIRQ-FYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHA 294 + E + Q ++ E E+ K L + E +IF+N ++ D L + + Sbjct: 297 IGSAGKPHERVEQKVFLMSESEKRK--KLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEK 354 Query: 295 RDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRE 354 + +HG Q++R+ + ++G+ +L+ TD+ RGID+Q VS+V+NYD+ N E Sbjct: 355 MGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIE 414 Query: 355 NYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI-ETFYNTSIEEMPLNVAD 404 +YIHRIGR GR G+ GVAI +T+ED ++ + + + P +A+ Sbjct: 415 DYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELAN 465 >3JCR-F nrPDB Length = 820 Score = 203 bits (516), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 123/386 (31%), Positives = 201/386 (52%), Gaps = 39/386 (10%) Query: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90 + S+ D +L +L I G+++P+ IQ++AI ++ D+I A++G+GKTA F I + Sbjct: 390 IRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPL 449 Query: 91 L---------QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVR 141 L +IE + A++LAPTRELAQQI++ + G +G A IGG + Sbjct: 450 LVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISRE 509 Query: 142 AEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQ 201 + +L+M I++ TPGR+ D+L RYL VLDEAD M+ GF+ + I + Sbjct: 510 DQGFRLRMGC-EIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILE 568 Query: 202 KL--------------------------NSNTQVVLLSATMPSDVLEVTKKFMRDPIRIL 235 + + Q V+ +ATMP V + + ++R P + Sbjct: 569 HMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVY 628 Query: 236 VKKEELTLEGIRQ-FYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHA 294 + E + Q ++ E E+ K L + E +IF+N ++ D L + + Sbjct: 629 IGSAGKPHERVEQKVFLMSESEKRK--KLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEK 686 Query: 295 RDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRE 354 + +HG Q++R+ + ++G+ +L+ TD+ RGID+Q VS+V+NYD+ N E Sbjct: 687 MGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIE 746 Query: 355 NYIHRIGRGGRFGRKGVAINMVTEED 380 +YIHRIGR GR G+ GVAI +T+ED Sbjct: 747 DYIHRIGRTGRAGKSGVAITFLTKED 772 >2I4I-A nrPDB Length = 417 Score = 201 bits (511), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 127/398 (31%), Positives = 211/398 (53%), Gaps = 25/398 (6%) Query: 25 SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIK-GYDVIAQAQSGTGKT 83 +N ++SF D+ + E ++ I + +P+ +Q+ AI P IK D++A AQ+G+GKT Sbjct: 8 NNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAI-PIIKEKRDLMACAQTGSGKT 66 Query: 84 ATFAISILQQIELD-----LKATQ-------------ALVLAPTRELAQQIQKVVMALGD 125 A F + IL QI D L+A + +LVLAPTRELA QI + Sbjct: 67 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 126 Query: 126 YMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD 185 GG ++ +++ L+ H++V TPGR+ DM+ R + + K VLDEAD Sbjct: 127 RSRVRPCVVYGGADIGQQIRDLE-RGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEAD 185 Query: 186 EMLSRGFKDQIYDIFQK----LNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241 ML GF+ QI I ++ ++ SAT P ++ + + F+ + I + V + Sbjct: 186 RMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGS 245 Query: 242 TLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSA 301 T E I Q + VE + + L L T + ++F+ T++ D L + ++ + ++ Sbjct: 246 TSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTS 305 Query: 302 MHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIG 361 +HGD Q++R+ + +FRSG S +L+ T + ARG+D+ V VIN+DLP++ E Y+HRIG Sbjct: 306 IHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIG 365 Query: 362 RGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMP 399 R GR G G+A + E + +D+ + +E+P Sbjct: 366 RTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVP 403 >6CZ5-A nrPDB Length = 480 Score = 200 bits (509), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 127/398 (31%), Positives = 210/398 (52%), Gaps = 25/398 (6%) Query: 25 SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIK-GYDVIAQAQSGTGKT 83 +N ++SF D+ + E ++ I + +P+ +Q+ AI P IK D++A AQ+G GKT Sbjct: 46 NNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAI-PIIKEKRDLMACAQTGCGKT 104 Query: 84 ATFAISILQQIELD-----LKATQ-------------ALVLAPTRELAQQIQKVVMALGD 125 A F + IL QI D L+A + +LVLAPTRELA QI + Sbjct: 105 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 164 Query: 126 YMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD 185 GG ++ +++ L+ H++V TPGR+ DM+ R + + K VLDEAD Sbjct: 165 RSRVRPCVVYGGADIGQQIRDLE-RGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEAD 223 Query: 186 EMLSRGFKDQIYDIFQK----LNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241 ML GF+ QI I ++ ++ SAT P ++ + + F+ + I + V + Sbjct: 224 RMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGS 283 Query: 242 TLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSA 301 T E I Q + VE + + L L T + ++F+ T++ D L + ++ + ++ Sbjct: 284 TSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTS 343 Query: 302 MHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIG 361 +HGD Q++R+ + +FRSG S +L+ T + ARG+D+ V VIN+DLP++ E Y+HRIG Sbjct: 344 IHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIG 403 Query: 362 RGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMP 399 R GR G G+A + E + +D+ + +E+P Sbjct: 404 RTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVP 441 >5DTU-A nrPDB Length = 475 Score = 196 bits (498), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 119/402 (29%), Positives = 207/402 (51%), Gaps = 36/402 (8%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92 ++++ L LL +Y G+++P+ IQ+ AI ++ D+I A +G+GKTA F + +L Sbjct: 43 NWEESGLPRRLLDIVYRVGYDEPTPIQRAAIPIALQARDLIGVAVTGSGKTAAFLLPLLV 102 Query: 93 QIELDLKATQ--------ALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEV 144 I T+ AL+LAPTREL QQI+ D +G + + +GG ++ + Sbjct: 103 YISELPPLTEYNKNDGPYALILAPTRELVQQIESEARKFADPLGFTVVSIVGGHSLEEQA 162 Query: 145 QKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLN 204 L+ A IIV TPGR+ D + RR L ++DEAD M+ +GF++ + I L Sbjct: 163 FALRNGA-EIIVATPGRLVDCIERRLLVFSQCCYVIMDEADRMIDQGFEEPLTKILDALP 221 Query: 205 SNT-------------------------QVVLLSATMPSDVLEVTKKFMRDPIRILVKKE 239 + Q ++ +ATMP V ++ KK++R P + + Sbjct: 222 VSNEKPDTEDAENPQLMSRYLGGRDRYRQTMMYTATMPPTVEKIAKKYLRRPAIVTIGNA 281 Query: 240 ELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVI-FINTRRKVDWLTEKMHARDFT 298 ++ + Q + E+ + L ++ + +I F+N +R + + + + + F+ Sbjct: 282 GEAVDTVEQRVEFIAGEDKRKRRLQEILNSGQFKPPIIVFVNIKRNCEMVAKDIKSWGFS 341 Query: 299 VSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIH 358 +HG Q++R+ + R+G + +L+ TDL RGIDV VSLV+N+++P+ E Y H Sbjct: 342 TVTLHGSKTQEQREASLAALRNGQAHILVATDLAGRGIDVPDVSLVVNFNMPSTIEAYTH 401 Query: 359 RIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYN-TSIEEMP 399 RIGR GR G+ GVAI + ED + D++ + +SI ++P Sbjct: 402 RIGRTGRAGKSGVAITFLGNEDADVMYDLKQIISKSSISKVP 443 >4D25-A nrPDB Length = 434 Score = 193 bits (491), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 116/388 (29%), Positives = 200/388 (51%), Gaps = 16/388 (4%) Query: 26 NWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTAT 85 N ++SF+ NL + +L + G+ KP+ IQ+ AI + G D++ AQ+G+GKTA Sbjct: 44 NPPRPIESFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTGSGKTAA 103 Query: 86 FAISILQQIELDLK---------ATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIG 136 F + I+ + D K Q ++++PTREL QI G Sbjct: 104 FLVPIINMLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNEARKFSYGSVLKVAVAYG 163 Query: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 196 GT VR + + HI+V TPGR+ D + R +S ++ VLD+AD ML GF I Sbjct: 164 GTAVRHQGDNIA-RGCHILVATPGRLHDFVERNRVSFGSVRFVVLDQADCMLDMGFMPSI 222 Query: 197 YDIFQKLN----SNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYIN 252 + + Q ++ SAT P D+ + +F+ + + + V + Q +I Sbjct: 223 EKMMLHPTMVETTKRQTLMFSATFPEDIQHLAGRFLNNYLFVAVGIVGGASTDVEQIFIE 282 Query: 253 VEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERD 312 V + E K ++L L E + ++F+ T+R D++ + + S++HGD Q+ER+ Sbjct: 283 VTKYE-KRNSLKQLIEENDGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQRERE 341 Query: 313 VIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVA 372 ++ F+SG +L+ T + ARG+D++ V +V+NYDLP + + Y+HRIGR GR G +G A Sbjct: 342 EALQNFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRVGNRGKA 401 Query: 373 INMV-TEEDKRTLRDIETFYNTSIEEMP 399 ++ +++D + D+ + + +P Sbjct: 402 VSFYDSDQDLALVADLSKILRQADQSVP 429 >2DB3-A nrPDB Length = 434 Score = 193 bits (490), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 111/375 (29%), Positives = 204/375 (54%), Gaps = 14/375 (3%) Query: 19 PEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQS 78 P V S+ + + F +L + ++ + G++ P+ IQ+ +I G D++A AQ+ Sbjct: 43 PVKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQT 102 Query: 79 GTGKTATFAISILQQI-----ELDLKATQALVLAPTRELAQQI--QKVVMALGDYMGASC 131 G+GKTA F + IL ++ EL+L Q ++++PTRELA QI + A Y+ Sbjct: 103 GSGKTAAFLLPILSKLLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGI 162 Query: 132 HACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRG 191 GGT+ R + + + H+++ TPGR+ D ++R +++ + + VLDEAD ML G Sbjct: 163 --VYGGTSFRHQNECI-TRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMG 219 Query: 192 FKDQIYDIFQK--LNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQF 249 F + + I + Q ++ SAT P ++ + +F+++ + + + ++Q Sbjct: 220 FSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQT 279 Query: 250 YINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQK 309 V + + + L E T ++F+ T+R D+L + ++F +++HGD Q Sbjct: 280 IYEVNKYAKRSKLIEILSEQADGT--IVFVETKRGADFLASFLSEKEFPTTSIHGDRLQS 337 Query: 310 ERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRK 369 +R+ +R+F++GS +VLI T + +RG+D++ + VINYD+P+ ++Y+HRIGR GR G Sbjct: 338 QREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNN 397 Query: 370 GVAINMVTEEDKRTL 384 G A + E R + Sbjct: 398 GRATSFFDPEKDRAI 412 >4KBG-A nrPDB Length = 365 Score = 190 bits (482), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 110/334 (32%), Positives = 179/334 (53%), Gaps = 21/334 (6%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F D L +L ++ G P+ IQ A+ ++G D+I QA++GTGKT FA+ I ++ Sbjct: 3 FKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAER 62 Query: 94 IELDL---KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQME 150 + + +ALVL PTRELA Q+ + A+ ++ A GGT + + L + Sbjct: 63 LAPSQERGRKPRALVLTPTRELALQVASELTAVAPHL--KVVAVYGGTGYGKQKEAL-LR 119 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV 210 +V TPGR D L + L +++ VLDEADEMLS GF++++ + + Q + Sbjct: 120 GADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTL 179 Query: 211 LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVERE------EWKLDTLC 264 L SAT+PS + +++M++P+ I V K+E + E E +L+ L Sbjct: 180 LFSATLPSWAKRLAERYMKNPVLINVIKDE---------PVTYEEEAVPAPVRGRLEVLS 230 Query: 265 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 324 DL + +A++F T+ + + + + + A+HGD+ Q ER+ ++ FR G R Sbjct: 231 DLLYVASPDRAMVFTRTKAETEEIAQGLLRLGHPAQALHGDLSQGERERVLGAFRQGEVR 290 Query: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIH 358 VL+ TD+ ARG+D+ QV LV++Y LP E Y H Sbjct: 291 VLVATDVAARGLDIPQVDLVVHYRLPDRAEAYQH 324 >4W7S-A nrPDB Length = 463 Score = 179 bits (453), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 122/379 (32%), Positives = 199/379 (52%), Gaps = 37/379 (9%) Query: 52 FEKPSAIQQRAILP--C-IKGY-DVIAQAQSGTGKTATFAISILQQIELD---------L 98 F P+ IQ R +P C +K Y D + A +G+GKT F I IL ++ + Sbjct: 69 FPSPTPIQ-RITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPILIKMSRSPPRPPSLKII 127 Query: 99 KATQALVLAPTRELAQQIQKVVMALGD-YMGASCHAC-----IGGTNVRAEVQKLQMEAP 152 +AL+LAPTREL QQIQK + + S + C +GG ++ E+ E Sbjct: 128 DGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLE-EISFSLSEGC 186 Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT----- 207 I+V TPGR+ D L L K ++ VLDEAD+M+ GF+DQ+ +I K++ N Sbjct: 187 DILVATPGRLIDSLENHLLVMKQVETLVLDEADKMIDLGFEDQVTNILTKVDINADSAVN 246 Query: 208 -QVVLLSATMPSDVLEVTKKFMRDPIRILVKKE---ELTLEGIRQFYINVEREEWKLDTL 263 Q ++ +ATM + ++ +M+ P+ + E E ++ + ++ N E + KL + Sbjct: 247 RQTLMFTATMTPVIEKIAAGYMQKPVYATIGVETGSEPLIQQVVEYADNDEDKFKKLKPI 306 Query: 264 CDLYETLTITQAVIFINTRRKVDWLTEKMHAR-DFTVSAMHGDMDQKERDVIMREFRSGS 322 Y+ I IFIN ++ DWL EK + V+ +HG Q++R+ ++ FR+ Sbjct: 307 VAKYDPPII----IFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQREHSLQLFRTNK 362 Query: 323 SRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKR 382 +++I T++ ARG+D+ VSLV+N+ + ++YIHRIGR GR +G A++ V+ + Sbjct: 363 VQIMIATNVAARGLDIPNVSLVVNFQISKKMDDYIHRIGRTGRAANEGTAVSFVSAAEDE 422 Query: 383 TLRDIETFYNTSIEEMPLN 401 +L I Y + PLN Sbjct: 423 SL--IRELYKYVRKHDPLN 439 >5ZWN-y nrPDB Length = 588 Score = 178 bits (452), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 121/379 (31%), Positives = 198/379 (52%), Gaps = 37/379 (9%) Query: 52 FEKPSAIQQRAILPCI---KGY-DVIAQAQSGTGKTATFAISILQQIELD---------L 98 F P+ IQ R +P + K Y D + A +G+GKT F I IL ++ + Sbjct: 194 FPSPTPIQ-RITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPILIKMSRSPPRPPSLKII 252 Query: 99 KATQALVLAPTRELAQQIQKVVMALGD-YMGASCHAC-----IGGTNVRAEVQKLQMEAP 152 +AL+LAPTREL QQIQK + + S + C +GG ++ E+ E Sbjct: 253 DGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLE-EISFSLSEGC 311 Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT----- 207 I+V TPGR+ D L L K ++ VLDEAD+M+ GF+DQ+ +I K++ N Sbjct: 312 DILVATPGRLIDSLENHLLVMKQVETLVLDEADKMIDLGFEDQVTNILTKVDINADSAVN 371 Query: 208 -QVVLLSATMPSDVLEVTKKFMRDPIRILVKKE---ELTLEGIRQFYINVEREEWKLDTL 263 Q ++ +ATM + ++ +M+ P+ + E E ++ + ++ N E + KL + Sbjct: 372 RQTLMFTATMTPVIEKIAAGYMQKPVYATIGVETGSEPLIQQVVEYADNDEDKFKKLKPI 431 Query: 264 CDLYETLTITQAVIFINTRRKVDWLTEKMHAR-DFTVSAMHGDMDQKERDVIMREFRSGS 322 Y+ I IFIN ++ DWL EK + V+ +HG Q++R+ ++ FR+ Sbjct: 432 VAKYDPPII----IFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQREHSLQLFRTNK 487 Query: 323 SRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKR 382 +++I T++ ARG+D+ VSLV+N+ + ++YIHRIGR GR +G A++ V+ + Sbjct: 488 VQIMIATNVAARGLDIPNVSLVVNFQISKKMDDYIHRIGRTGRAANEGTAVSFVSAAEDE 547 Query: 383 TLRDIETFYNTSIEEMPLN 401 +L I Y + PLN Sbjct: 548 SL--IRELYKYVRKHDPLN 564 >6CB1-p nrPDB Length = 505 Score = 177 bits (448), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 118/388 (30%), Positives = 206/388 (53%), Gaps = 18/388 (4%) Query: 24 ESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKT 83 E V+ F+++ LS+ L+ I GF +++Q R I P + G DV+ A++G+GKT Sbjct: 34 EGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKT 93 Query: 84 ATF---AISILQQIELDLK-ATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 139 F AI +L ++ + T +V+ PTRELA QI V L ++ + IGG N Sbjct: 94 LAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGAN 153 Query: 140 VRAEVQKLQMEAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYD 198 R E +KL M+ ++++ TPGR+ D L N + K +K ++DEAD +L GF+D++ Sbjct: 154 RRQEAEKL-MKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQ 212 Query: 199 IFQKL-NSNTQVVLLSATMPSDVLEVTKKFMRDP---IRILVKKEELTLEGIRQFYINVE 254 I + L N + Q +L SAT + V ++ + +R I ++ + + T +G+ Q Y+ + Sbjct: 213 IIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCD 272 Query: 255 REEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVI 314 ++ L L + + ++F+++ V + E ++ D V +HG Q++R Sbjct: 273 SDKRFL-LLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNT 331 Query: 315 MREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR-KGVAI 373 EF + +LI TD+ ARG+D+ V +I +D P + +YIHR+GR R + KG ++ Sbjct: 332 FFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSL 391 Query: 374 NMVTEEDKRTLRDIETFYNTSIEEMPLN 401 +T + LR ++ ++PLN Sbjct: 392 MFLTPNELGFLRYLKA------SKVPLN 413 >2Z0M-A nrPDB Length = 337 Score = 170 bits (431), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 108/341 (31%), Positives = 184/341 (53%), Gaps = 18/341 (5%) Query: 39 LSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDL 98 ++E + + I GF+ + +Q + I ++G +V+ +A++G+GKTA +AI IL EL + Sbjct: 1 MNEKIEQAIREMGFKNFTEVQSKTIPLMLQGKNVVVRAKTGSGKTAAYAIPIL---ELGM 57 Query: 99 KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGT 158 K+ LV+ PTREL +Q+ + +G YM GG +A++ +++ I+V T Sbjct: 58 KS---LVVTPTRELTRQVASHIRDIGRYMDTKVAEVYGGMPYKAQINRVR--NADIVVAT 112 Query: 159 PGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPS 218 PGR+ D+ ++ + ++ ++DEAD M GF D I I + ++ L SAT+P Sbjct: 113 PGRLLDLWSKGVIDLSSFEIVIIDEADLMFEMGFIDDIKIILAQTSNRKITGLFSATIPE 172 Query: 219 DVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIF 278 ++ +V K F+ + I + + L + +++V +++W+ + L E ++F Sbjct: 173 EIRKVVKDFITNYEEI---EACIGLANVEHKFVHV-KDDWR-SKVQALRENKD-KGVIVF 226 Query: 279 INTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDV 338 + TR +V L + GD+ Q R+ + FR G +LITTD+ +RG+D+ Sbjct: 227 VRTRNRVAKLVRLFD----NAIELRGDLPQSVRNRNIDAFREGEYDMLITTDVASRGLDI 282 Query: 339 QQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE 379 V VIN+D P + YIHRIGR GR GRKG AI + E Sbjct: 283 PLVEKVINFDAPQDLRTYIHRIGRTGRMGRKGEAITFILNE 323 >4LJY-A nrPDB Length = 493 Score = 164 bits (414), Expect = 8e-41, Method: Compositional matrix adjust. Identities = 107/388 (27%), Positives = 193/388 (49%), Gaps = 41/388 (10%) Query: 25 SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTA 84 + W+++ S D M L L F + IQ +A+ + G DVI +++G+GKT Sbjct: 50 TKWSQLGLSTDTMVLITEKLH------FGSLTPIQSQALPAIMSGRDVIGISKTGSGKTI 103 Query: 85 TFAISILQQIELDLKATQ------ALVLAPTRELAQQIQKVVMALGDY---MGASCHACI 135 ++ + +L+Q++ ++ L+LAPTRELA QI + V + + + C C Sbjct: 104 SYLLPLLRQVKAQRPLSKHETGPMGLILAPTRELALQIHEEVTKFTEADTSIRSVC--CT 161 Query: 136 GGTNVRAEVQKLQMEAPHIIVGTPGRVFDML---NRRYLSPKYIKMFVLDEADEMLSRGF 192 GG+ ++ ++ L+ I+V TPGR D+L + + LS K I V+DEAD + GF Sbjct: 162 GGSEMKKQITDLK-RGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEADRLFDLGF 220 Query: 193 KDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYIN 252 + QI I + + + Q VL SAT P+ + + + PI I + + + E ++Q + Sbjct: 221 EPQITQIMKTVRPDKQCVLFSATFPNKLRSFAVRVLHSPISITINSKGMVNENVKQKFRI 280 Query: 253 VEREEWKLDTLCDLYETLTI--------------------TQAVIFINTRRKVDWLTEKM 292 E+ K D L L + +A+IF++++ D++++K+ Sbjct: 281 CHSEDEKFDNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKL 340 Query: 293 HARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTN 352 A+H +ER + + +F+ + +L+ T++L+RG++V +VSLVI Y+ Sbjct: 341 LNAGIVTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKT 400 Query: 353 RENYIHRIGRGGRFGRKGVAINMVTEED 380 Y+H GR R R G AI ++ ++ Sbjct: 401 FAQYVHTTGRTARGSRSGTAITLLLHDE 428 >2OXC-A nrPDB Length = 230 Score = 160 bits (404), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 86/200 (43%), Positives = 128/200 (64%), Gaps = 4/200 (2%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F+ + LS +L G+ A GFE+PS +Q +AI G D+I QA+SGTGKT F+ L Sbjct: 26 FESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDS 85 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAP 152 + L+ +TQ L+LAPTRE+A QI V+ A+G M G CH IGGT + + K +++ Sbjct: 86 LVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQD--KTRLKKC 143 Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRG-FKDQIYDIFQKLNSNTQVVL 211 HI VG+PGR+ ++ YL+P I++F+LDEAD++L G F++QI I+ L ++ Q++ Sbjct: 144 HIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLA 203 Query: 212 LSATMPSDVLEVTKKFMRDP 231 +SAT P + K+MRDP Sbjct: 204 VSATYPEFLANALTKYMRDP 223 >3I62-A nrPDB Length = 563 Score = 158 bits (399), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 116/389 (29%), Positives = 197/389 (50%), Gaps = 34/389 (8%) Query: 39 LSESLLRGIYAYGFEKPSAIQQRAILPCIKG--YDVIAQAQSGTGKTATFAISILQQI-- 94 L + + + I F + +QQ+ I P + +DVIA+A++GTGKT F I I Q + Sbjct: 79 LDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLIN 138 Query: 95 -ELDLK-ATQALVLAPTRELAQQIQKVVMALGDY-MGASCHACI---GGTNVRAEVQKLQ 148 + D + +A+++APTR+LA QI+ V + D G +AC+ GGT+ RA + K+ Sbjct: 139 TKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMN 198 Query: 149 MEAPHIIVGTPGRVFDMLNRRYLSPKYIKMF---VLDEADEMLSRGFKDQIYDIFQKLNS 205 P+I++ TPGR+ D+L + S K+ + VLDEAD +L GF+D + I LN Sbjct: 199 KLRPNIVIATPGRLIDVLEK--YSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNE 256 Query: 206 -------NTQVVLLSATMPSDVLEVTKKFMRDPIRILV----KKEELTLEGIRQFYINVE 254 N + +L SAT+ V ++ M + + K E E I Q + E Sbjct: 257 KNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISE 316 Query: 255 REEWKLDTLCD-----LYETLTITQAVIFINTRRKVDWLTEKMH---ARDFTVSAMHGDM 306 + + + + E + +A+IF T + +L + +D + HG + Sbjct: 317 KFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKI 376 Query: 307 DQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRF 366 Q +R +++ F+ S +L+ TD+ ARG+D V V+ +P+ NYIHRIGR R Sbjct: 377 TQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARS 436 Query: 367 GRKGVAINMVTEEDKRTLRDIETFYNTSI 395 G++G ++ + +++ +R++E N I Sbjct: 437 GKEGSSVLFICKDELPFVRELEDAKNIVI 465 >3SQW-A nrPDB Length = 579 Score = 158 bits (399), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 116/389 (29%), Positives = 197/389 (50%), Gaps = 34/389 (8%) Query: 39 LSESLLRGIYAYGFEKPSAIQQRAILPCIKG--YDVIAQAQSGTGKTATFAISILQQI-- 94 L + + + I F + +QQ+ I P + +DVIA+A++GTGKT F I I Q + Sbjct: 28 LDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLIN 87 Query: 95 -ELDLK-ATQALVLAPTRELAQQIQKVVMALGDY-MGASCHACI---GGTNVRAEVQKLQ 148 + D + +A+++APTR+LA QI+ V + D G +AC+ GGT+ RA + K+ Sbjct: 88 TKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMN 147 Query: 149 MEAPHIIVGTPGRVFDMLNRRYLSPKYIKMF---VLDEADEMLSRGFKDQIYDIFQKLNS 205 P+I++ TPGR+ D+L + S K+ + VLDEAD +L GF+D + I LN Sbjct: 148 KLRPNIVIATPGRLIDVLEK--YSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNE 205 Query: 206 -------NTQVVLLSATMPSDVLEVTKKFMRDPIRILV----KKEELTLEGIRQFYINVE 254 N + +L SAT+ V ++ M + + K E E I Q + E Sbjct: 206 KNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISE 265 Query: 255 REEWKLDTLCD-----LYETLTITQAVIFINTRRKVDWLTEKMH---ARDFTVSAMHGDM 306 + + + + E + +A+IF T + +L + +D + HG + Sbjct: 266 KFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKI 325 Query: 307 DQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRF 366 Q +R +++ F+ S +L+ TD+ ARG+D V V+ +P+ NYIHRIGR R Sbjct: 326 TQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARS 385 Query: 367 GRKGVAINMVTEEDKRTLRDIETFYNTSI 395 G++G ++ + +++ +R++E N I Sbjct: 386 GKEGSSVLFICKDELPFVRELEDAKNIVI 414 >5GJU-A nrPDB Length = 205 Score = 155 bits (392), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 81/200 (40%), Positives = 119/200 (59%), Gaps = 2/200 (1%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92 +F D+ L +L + G+EKPS IQ I + G DV+ AQ+G+GKTA F++ +LQ Sbjct: 2 TFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQ 61 Query: 93 QIELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEA 151 ++ +LKA Q LVLAPTRELA Q+ + + +M G + A GG +++ L+ + Sbjct: 62 NLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQLRALR-QG 120 Query: 152 PHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL 211 P I+VGTPGR+ D L R L + VLDEADEML GF + + I ++ Q L Sbjct: 121 PQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIPEGHQTAL 180 Query: 212 LSATMPSDVLEVTKKFMRDP 231 SATMP + +T++FM++P Sbjct: 181 FSATMPEAIRRITRRFMKEP 200 >1VEC-A nrPDB Length = 206 Score = 150 bits (380), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 75/204 (36%), Positives = 125/204 (61%), Gaps = 2/204 (0%) Query: 32 DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL 91 + F+D L LL GI+ G+EKPS IQ+ +I + G D++A+A++GTGK+ + I +L Sbjct: 3 NEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL 62 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQME 150 ++++L QA+V+ PTRELA Q+ ++ + + +M GA A GGTN+R ++ +L + Sbjct: 63 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLD-D 121 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV 210 H+++ TPGR+ D++ + +++M VLDEAD++LS+ F + DI L N Q++ Sbjct: 122 TVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQIL 181 Query: 211 LLSATMPSDVLEVTKKFMRDPIRI 234 L SAT P V + + P I Sbjct: 182 LYSATFPLSVQKFMNSHLEKPYEI 205 >1T6N-A nrPDB Length = 220 Score = 148 bits (374), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 81/205 (39%), Positives = 115/205 (56%), Gaps = 2/205 (0%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F D L LLR I GFE PS +Q I I G DV+ QA+SG GKTA F ++ LQQ Sbjct: 16 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 75 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAP 152 +E LV+ TRELA QI K YM GG +++ + + L+ P Sbjct: 76 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 135 Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQVVL 211 HI+VGTPGR+ + + L+ K+IK F+LDE D+ML + + + +IF+ QV++ Sbjct: 136 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 195 Query: 212 LSATMPSDVLEVTKKFMRDPIRILV 236 SAT+ ++ V +KFM+DP+ I V Sbjct: 196 FSATLSKEIRPVCRKFMQDPMEIFV 220 >6AIC-A nrPDB Length = 214 Score = 146 bits (368), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 73/202 (36%), Positives = 125/202 (61%), Gaps = 3/202 (1%) Query: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90 + +F ++ +S++ ++ + + GF++P+ IQ+ +I ++G D++ QAQ+GTGKT F I + Sbjct: 1 MQNFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPL 60 Query: 91 LQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQME 150 ++++ + + Q+L+LAPTRELA Q+ + + G GG + +++ L+ + Sbjct: 61 IEKV-VGKQGVQSLILAPTRELAMQVAEQLREFSRGQGVQVVTVFGGMPIERQIKALK-K 118 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNS-NTQV 209 P I+VGTPGRV D LNRR L I +LDEADEM++ GF D + I K+ + Q Sbjct: 119 GPQIVVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMMNMGFIDDMRFIMDKIPAVQRQT 178 Query: 210 VLLSATMPSDVLEVTKKFMRDP 231 +L SATMP + + ++FM+ P Sbjct: 179 MLFSATMPKAIQALVQQFMKSP 200 >3FHC-B nrPDB Length = 235 Score = 140 bits (354), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 9/215 (4%) Query: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCI---KGYDVIAQAQSGTGKTATFA 87 V SF+++ L LL+G+YA GF +PS IQ+ A LP + ++IAQ+QSGTGKTA F Sbjct: 24 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENA-LPLMLAEPPQNLIAQSQSGTGKTAAFV 82 Query: 88 ISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKL 147 +++L Q+E K Q L L+PT ELA Q KV+ +G + A N QK+ Sbjct: 83 LAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKI 142 Query: 148 QMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEML-SRGFKDQIYDIFQKLNS 205 + I++GTPG V D ++ +++ PK IK+FVLDEAD M+ ++G +DQ I + L Sbjct: 143 ---SEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPR 199 Query: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240 N Q++L SAT V + +K + DP I +K+EE Sbjct: 200 NCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREE 234 >2KBE-A nrPDB Length = 226 Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 82/200 (41%), Positives = 126/200 (63%), Gaps = 10/200 (5%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCI---KGYDVIAQAQSGTGKTATFAIS 89 SFD++ L+ LL+GIYA F+KPS IQ+RA LP + ++IAQ+QSGTGKTA F+++ Sbjct: 23 SFDELGLAPELLKGIYAMKFQKPSKIQERA-LPLLLHNPPRNMIAQSQSGTGKTAAFSLT 81 Query: 90 ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQM 149 +L ++ + + QA+ LAP+RELA+Q +VV +G + + + + + + Q+ Sbjct: 82 MLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDSFEKNK----QI 137 Query: 150 EAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEML-SRGFKDQIYDIFQKLNSNTQ 208 A +IVGTPG V D++ R+ + + IK+FVLDEAD ML +G DQ + + L +TQ Sbjct: 138 NA-QVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQ 196 Query: 209 VVLLSATMPSDVLEVTKKFM 228 +VL SAT V + KK + Sbjct: 197 LVLFSATFADAVRQYAKKIV 216 >3FMO-B nrPDB Length = 300 Score = 139 bits (350), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 87/214 (40%), Positives = 128/214 (59%), Gaps = 9/214 (4%) Query: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCI---KGYDVIAQAQSGTGKTATFA 87 V SF+++ L LL+G+YA GF +PS IQ+ A LP + ++IAQ+QSGTGKTA F Sbjct: 91 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENA-LPLMLAEPPQNLIAQSQSGTGKTAAFV 149 Query: 88 ISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKL 147 +++L Q+E K Q L L+PT ELA Q KV+ +G + A N QK+ Sbjct: 150 LAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKI 209 Query: 148 QMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEMLS-RGFKDQIYDIFQKLNS 205 + I++GTPG V D ++ +++ PK IK+FVLDEAD M++ +G +DQ I + L Sbjct: 210 ---SEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPR 266 Query: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKE 239 N Q++L SAT V + +K + DP I +K+E Sbjct: 267 NCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 300 >1WRB-A nrPDB Length = 253 Score = 124 bits (310), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 74/234 (31%), Positives = 129/234 (55%), Gaps = 18/234 (7%) Query: 30 IVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAIS 89 ++++FD++ L ++ I +++P+ IQ+ AI ++ D++A AQ+G+GKTA F I Sbjct: 21 VIENFDELKLDPTIRNNILLASYQRPTPIQKNAIPAILEHRDIMACAQTGSGKTAAFLIP 80 Query: 90 IL---------QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACI--GGT 138 I+ QQ + L+LAPTRELA QI + +C+ GG Sbjct: 81 IINHLVCQDLNQQRYSKTAYPKCLILAPTRELAIQILSESQKFS--LNTPLRSCVVYGGA 138 Query: 139 NVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYD 198 + ++++++QM H++V TPGR+ D + + +S ++ K VLDEAD ML GF+ QI Sbjct: 139 DTHSQIREVQMGC-HLLVATPGRLVDFIEKNKISLEFCKYIVLDEADRMLDMGFEPQIRK 197 Query: 199 IFQKLNS----NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQ 248 I ++ N N Q ++ SAT P ++ ++ F+ + I + V + T + I+Q Sbjct: 198 IIEESNMPSGINRQTLMFSATFPKEIQKLAADFLYNYIFMTVGRVGSTSDSIKQ 251 >2GXQ-A nrPDB Length = 207 Score = 123 bits (308), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 71/208 (34%), Positives = 115/208 (55%), Gaps = 6/208 (2%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F D L +L ++ G P+ IQ A+ ++G D+I QA++GTGKT FA+ I ++ Sbjct: 3 FKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAER 62 Query: 94 IELDL---KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQME 150 + + +ALVL PTRELA Q+ + A+ ++ A GGT + + L + Sbjct: 63 LAPSQERGRKPRALVLTPTRELALQVASELTAVAPHL--KVVAVYGGTGYGKQKEAL-LR 119 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV 210 +V TPGR D L + L +++ VLDEADEMLS GF++++ + + Q + Sbjct: 120 GADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTL 179 Query: 211 LLSATMPSDVLEVTKKFMRDPIRILVKK 238 L SAT+PS + +++M++P+ I V K Sbjct: 180 LFSATLPSWAKRLAERYMKNPVLINVIK 207 >1Q0U-A nrPDB Length = 219 Score = 121 bits (304), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 67/204 (32%), Positives = 114/204 (55%), Gaps = 9/204 (4%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F ++ I F KP+ IQ+R I ++G ++ Q+Q+GTGKT + + I+++ Sbjct: 6 FTRFPFQPFIIEAIKTLRFYKPTEIQERIIPGALRGESMVGQSQTGTGKTHAYLLPIMEK 65 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDY------MGASCHACIGGTNVRAEVQKL 147 I+ + QA++ APTRELA QI + + + + A C IGGT+ + ++KL Sbjct: 66 IKPERAEVQAVITAPTRELATQIYHETLKITKFCPKDRMIVARC--LIGGTDKQKALEKL 123 Query: 148 QMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT 207 ++ PHI++GTPGR+ D + + L + V+DEAD ML GF + I ++ + Sbjct: 124 NVQ-PHIVIGTPGRINDFIREQALDVHTAHILVVDEADLMLDMGFITDVDQIAARMPKDL 182 Query: 208 QVVLLSATMPSDVLEVTKKFMRDP 231 Q+++ SAT+P + KK+M +P Sbjct: 183 QMLVFSATIPEKLKPFLKKYMENP 206 >3BER-A nrPDB Length = 249 Score = 121 bits (304), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 70/209 (33%), Positives = 117/209 (55%), Gaps = 2/209 (0%) Query: 29 EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAI 88 E +F D+ +++ L G+ KP+ IQ AI ++G D+I A++G+GKT FA+ Sbjct: 40 EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFAL 99 Query: 89 SILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQ 148 IL + + ALVL PTRELA QI + ALG +G +GG + ++ L Sbjct: 100 PILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL- 158 Query: 149 MEAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT 207 + PHII+ TPGR+ D L N + + + +K V+DEAD +L+ F+ ++ I + + + Sbjct: 159 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 218 Query: 208 QVVLLSATMPSDVLEVTKKFMRDPIRILV 236 + L SATM V ++ + +++P++ V Sbjct: 219 KTFLFSATMTKKVQKLQRAALKNPVKCAV 247 >5H1Y-A nrPDB Length = 281 Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 66/222 (29%), Positives = 111/222 (50%), Gaps = 15/222 (6%) Query: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90 + SF +M ++LRG+ G P+ IQ + I + G D+I A +G+GKT F + + Sbjct: 51 IKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPV 110 Query: 91 L-----QQIELDL---KATQALVLAPTRELAQQIQKVVMALGDYMGAS------CHACIG 136 + Q+ L + L++ P+RELA+Q ++ + C CIG Sbjct: 111 IMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIG 170 Query: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 196 G +V+ +++ ++ H++V TPGR+ D+L ++ +S + LDEAD M+ GF+ I Sbjct: 171 GMSVKEQMETIR-HGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDI 229 Query: 197 YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK 238 IF Q +L SATMP + K + P+ I V + Sbjct: 230 RTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGR 271 >5GVS-A nrPDB Length = 231 Score = 113 bits (283), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 65/218 (29%), Positives = 109/218 (50%), Gaps = 15/218 (6%) Query: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90 + SF +M ++LRG+ G P+ IQ + I + G D+I A +G+GKT F + + Sbjct: 12 IKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPV 71 Query: 91 L-----QQIELDL---KATQALVLAPTRELAQQIQKVVMALGDYMGAS------CHACIG 136 + Q+ L + L++ P+RELA+Q ++ + C CIG Sbjct: 72 IMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIG 131 Query: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 196 G +V+ +++ ++ H++V TPGR+ D+L ++ +S + LDEAD M+ GF+ I Sbjct: 132 GMSVKEQMETIR-HGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDI 190 Query: 197 YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRI 234 IF Q +L SATMP + K + P+ I Sbjct: 191 RTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTI 228 >3LY5-A nrPDB Length = 262 Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 82/240 (34%), Positives = 126/240 (52%), Gaps = 21/240 (8%) Query: 14 PDGMEPEGVIESNWNEIVDSFDDMNLS-------ESLLRGIYAYGFEKPSAIQQRAILPC 66 PD E E + S + +F+D + + E+ L+ I GF + IQ ++I P Sbjct: 29 PDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPL 88 Query: 67 IKGYDVIAQAQSGTGKTATFAISILQQIE----LDLKATQALVLAPTRELAQQIQKVVMA 122 ++G D++A A++G+GKT F I ++ I + T L+L+PTRELA Q V+ Sbjct: 89 LEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTRELAMQTFGVLKE 148 Query: 123 LGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFD-MLNRRYLSPKYIKMFVL 181 L + + +GG+N AE QKL +IIV TPGR+ D M N K ++ V+ Sbjct: 149 LMTHHVHTYGLIMGGSNRSAEAQKLG-NGINIIVATPGRLLDHMQNTPGFMYKNLQCLVI 207 Query: 182 DEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241 DEAD +L GF++++ I + L + Q +L SAT T+K + D RI +KKE L Sbjct: 208 DEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQ-------TRK-VEDLARISLKKEPL 259 >4PX9-A nrPDB Length = 292 Score = 106 bits (264), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 76/237 (32%), Positives = 122/237 (51%), Gaps = 25/237 (10%) Query: 25 SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIK-GYDVIAQAQSGTGKT 83 +N ++SF D+ + E ++ I + +P+ +Q+ AI P IK D++A AQ+G+GKT Sbjct: 58 NNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAI-PIIKEKRDLMACAQTGSGKT 116 Query: 84 ATFAISILQQIELD-----LKATQ-------------ALVLAPTRELAQQIQKVVMALGD 125 A F + IL QI D L+A + +LVLAPTRELA QI + Sbjct: 117 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 176 Query: 126 YMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD 185 GG ++ +++ L+ H++V TPGR+ DM+ R + + K VLDEAD Sbjct: 177 RSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGRLVDMMERGKIGLDFCKYLVLDEAD 235 Query: 186 EMLSRGFKDQIYDIFQKLNSNTQVV----LLSATMPSDVLEVTKKFMRDPIRILVKK 238 ML GF+ QI I ++ + V + SAT P ++ + + F+ + I + V + Sbjct: 236 RMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGR 292 >3FE2-A nrPDB Length = 242 Score = 105 bits (263), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 72/228 (31%), Positives = 114/228 (50%), Gaps = 20/228 (8%) Query: 26 NWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTAT 85 N + V +F + N +++ I F +P+AIQ + + G D++ AQ+G+GKT + Sbjct: 23 NCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLS 82 Query: 86 FAISILQQIELDL-----KATQALVLAPTRELAQQIQKVVMALGDYMGASCHAC------ 134 + + + I LVLAPTRELAQQ+Q+V +Y C AC Sbjct: 83 YLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVA---AEY----CRACRLKSTC 135 Query: 135 -IGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFK 193 GG +++ L+ I + TPGR+ D L + + VLDEAD ML GF+ Sbjct: 136 IYGGAPKGPQIRDLE-RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFE 194 Query: 194 DQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241 QI I ++ + Q ++ SAT P +V ++ + F++D I I + EL Sbjct: 195 PQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALEL 242 >2PL3-A nrPDB Length = 236 Score = 101 bits (252), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 66/219 (30%), Positives = 117/219 (53%), Gaps = 8/219 (3%) Query: 26 NWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTAT 85 N NEI F D LS+ L+G+ + + IQ++ I ++G DV+ A++G+GKT Sbjct: 20 NVNEIT-RFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLA 78 Query: 86 FAISILQQI-ELDLKATQAL---VLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVR 141 F + +L+ + L +T L +++PTRELA Q +V+ +G S IGG +++ Sbjct: 79 FLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 138 Query: 142 AEVQKLQMEAPHIIVGTPGRVFDMLNRRY-LSPKYIKMFVLDEADEMLSRGFKDQIYDIF 200 E +++ +I+V TPGR+ ++ ++M VLDEAD +L GF D + + Sbjct: 139 HEAERIN--NINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVI 196 Query: 201 QKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKE 239 + L Q +L SAT V ++ + +++P + V ++ Sbjct: 197 ENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEK 235 >3IUY-A nrPDB Length = 228 Score = 95.5 bits (236), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 65/202 (32%), Positives = 102/202 (50%), Gaps = 12/202 (5%) Query: 43 LLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQ 102 LL+ I G KP+ IQ +A ++G D+I AQ+GTGKT ++ + I LD + Sbjct: 31 LLKSIIRVGILKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGF--IHLDSQPIS 88 Query: 103 --------ALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHI 154 LVL PTRELA ++ Y G GG N +++ + + I Sbjct: 89 REQRNGPGMLVLTPTRELALHVEAECSKYS-YKGLKSICIYGGRNRNGQIEDIS-KGVDI 146 Query: 155 IVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSA 214 I+ TPGR+ D+ ++ + I V+DEAD+ML F+ QI I + + Q V+ SA Sbjct: 147 IIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSA 206 Query: 215 TMPSDVLEVTKKFMRDPIRILV 236 T P V ++ +++DP+ + V Sbjct: 207 TWPDTVRQLALSYLKDPMIVYV 228 >3DKP-A nrPDB Length = 245 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 58/197 (29%), Positives = 102/197 (51%), Gaps = 7/197 (3%) Query: 36 DMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIE 95 + ++ LL+ I GF+ P+ IQ +AI + G +++A A +G+GKT F+I IL Q++ Sbjct: 33 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 92 Query: 96 LDL-KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHI 154 K +AL+++PTRELA QI + ++ + + G H + + I Sbjct: 93 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 152 Query: 155 IVGTPGRVFDMLNR--RYLSPKYIKMFVLDEADEML---SRGFKDQIYDIFQKLNSN-TQ 208 +V TP R+ +L + + ++ V+DE+D++ GF+DQ+ IF S+ + Sbjct: 153 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 212 Query: 209 VVLLSATMPSDVLEVTK 225 + SAT DV + K Sbjct: 213 RAMFSATFAYDVEQWCK 229 >6CRM-A nrPDB Length = 541 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 80/374 (21%), Positives = 153/374 (40%), Gaps = 53/374 (14%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 + L++ +L+ + Y +P Q I ++G D + +G GK+ + I L Sbjct: 27 YSQETLAKQVLQETFGYQQFRPG--QATIIDAVLEGRDCLVVMPTGGGKSLCYQIPAL-- 82 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPH 153 +K +V++P L + ++A G AC+ T R E Q Sbjct: 83 ----VKTGLTIVVSPLISLMKDQVDQLLANG-----VAAACLNSTQSREEQQA------- 126 Query: 154 IIVGTPGRVFDMLNRRYLSPKYI--------------KMFVLDEADEMLSRG--FKDQIY 197 ++ G +L Y++P+ + M +DEA + G F+ + Sbjct: 127 VLAGCRTGQVRLL---YIAPERLMMDNFIDTLGYWDLAMVAVDEAHCISQWGHDFRPEYA 183 Query: 198 DIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRIL------VKKEELTLEGIRQFYI 251 + Q V ++ T +D + T+ RD +R+L ++ IR Y+ Sbjct: 184 ALGQLRARFPAVPFMALTATAD--DTTR---RDIVRLLGLDDPLIEISSFDRPNIR--YM 236 Query: 252 NVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKER 311 +E+ + LD L + +I+ N+R KV+ ++ +R + +A H ++ + R Sbjct: 237 LMEKFK-PLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSRGISAAAYHAGLEHEVR 295 Query: 312 DVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGV 371 + +F+ ++++ T GI+ V V+++D+P N E+Y GR GR G Sbjct: 296 ASVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAE 355 Query: 372 AINMVTEEDKRTLR 385 A+ D LR Sbjct: 356 AMLFYDPADMAWLR 369 >1OYY-A nrPDB Length = 523 Score = 57.8 bits (138), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 28/111 (25%), Positives = 54/111 (48%) Query: 275 AVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLAR 334 +I+ N+R KV+ ++ ++ + +A H ++ R + +F+ ++++ T Sbjct: 239 GIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGM 298 Query: 335 GIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLR 385 GI+ V V+++D+P N E+Y GR GR G A+ D LR Sbjct: 299 GINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADMAWLR 349 >5LST-A nrPDB Length = 693 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 82/359 (22%), Positives = 142/359 (39%), Gaps = 46/359 (12%) Query: 59 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 118 Q+RA++ + G + +G GK+ + + L + LV++P L + Sbjct: 62 QERAVMRILSGISTLLVLPTGAGKSLCYQLPAL--LYSRRSPCLTLVVSPLLSL---MDD 116 Query: 119 VVMALGDYMGASC-HACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFD---MLNRRYLSPK 174 V L + A+C H+ + + +QK++ H+++ TP + + L P Sbjct: 117 QVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPP- 175 Query: 175 YIKMFVLDEADEM--LSRGFKDQIYDIFQKLNSNTQV---VLLSATMPSDVLEVTKKFMR 229 + +DEA + S F+ + + L V + L+AT T++ Sbjct: 176 -VAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTAT-------ATRRTAS 227 Query: 230 DPIRILVKKEELTLEGIR------QFYINVERE-EWKLDTLCDLYETLTITQAVIFIN-- 280 D + L EE L G ++++R+ + L TL + +I+ N Sbjct: 228 DVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRR 287 Query: 281 --TRRKVDWLTEKMHA----------RDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328 T R L +HA T A H M +ER + R F G RV++ Sbjct: 288 EDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVA 347 Query: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTE--EDKRTLR 385 T G+D V V++ LP + E+Y+ +GR GR G+ + ED R LR Sbjct: 348 TVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELR 406 >5V9X-A nrPDB Length = 877 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 84/398 (21%), Positives = 159/398 (39%), Gaps = 76/398 (19%) Query: 35 DDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKT-ATFAISI--- 90 D + +L R + F P+ Q A +G + + A +G+GKT A F +I Sbjct: 28 DPLGRFSALTREWFTTAFAAPTPAQADAWSAISEGNNTLVIAPTGSGKTLAAFLWAIDRL 87 Query: 91 LQQIELDLKATQALVLAPTRELAQQIQK-------VVMALGDYMGASCHA-CIG---GTN 139 + TQ L ++P + LA +++ + + + G + +G G Sbjct: 88 ADPAREPSQGTQVLYVSPLKALAVDVERNLRTPLTGITRVAERHGLPAPSITVGVRSGDT 147 Query: 140 VRAEVQKLQMEAPHIIVGTPGRVFDMLN---RRYLSPKYIKMFVLDEADEMLS--RG--F 192 + + + P +++ TP +F ML R L+ ++ ++DE + + RG Sbjct: 148 PPNQRRAMIANPPDVLITTPESLFLMLTSAARETLT--SVRTVIVDEVHAVAATKRGAHL 205 Query: 193 KDQIYDIFQKLNSNTQVVLLSATM--PSDVLEVTKKFM--RDPIRILVKKEELTLEGIRQ 248 + + Q L++ Q + LSAT+ P +V +F+ + P I+ T + Q Sbjct: 206 ALSLERLDQLLDTPAQRIGLSATVRPPEEV----ARFLSGQAPTTIVCPPAAKTFDLSVQ 261 Query: 249 FYI----NVEREEWKLDT---LCDLYETLTITQAVIFINTRRKVDWLTEKMH-------- 293 + N++ D + DL E +++F N+RR + LT +++ Sbjct: 262 VPVPDMANLDNNSIWPDVEERIVDLVEAHN--SSIVFANSRRLAERLTSRLNEIHAERSG 319 Query: 294 ---------------------------ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVL 326 A A HG + +++R + + +SG R + Sbjct: 320 IELPAGPNPEVGGGAPAHLMGSGQANGAPPLLARAHHGSVSKEQRAQVEDDLKSGRLRAV 379 Query: 327 ITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGG 364 + T L GID+ V LVI + P + + + R+GR G Sbjct: 380 VATSSLELGIDMGAVDLVIQVEAPPSVASGLQRVGRAG 417 >4GL2-A nrPDB Length = 699 Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 14/104 (13%) Query: 274 QAVIFINTRRKV----DWLTEKMHARDFTVSAMH----------GDMDQKERDVIMREFR 319 + +IF TR+ W+TE + V A H M Q E+ ++ +FR Sbjct: 402 RGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFR 461 Query: 320 SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG 363 +G +LI T + G+D+++ ++VI Y L TN + GR Sbjct: 462 TGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA 505 >4Q48-A nrPDB Length = 525 Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 25/98 (25%), Positives = 42/98 (42%) Query: 275 AVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLAR 334 +++ +R+ V+ + + A+ A H + ER+ + F + ++ T Sbjct: 239 GIVYCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLNEEGVIVCATVAFGM 298 Query: 335 GIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVA 372 GID V V + DLP + E Y GR GR G A Sbjct: 299 GIDKPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTA 336 >1GM5-A nrPDB Length = 780 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 4/94 (4%) Query: 296 DFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNREN 355 +F + MHG + Q+E+D +M EF G +L++T ++ GIDV + ++++ + Sbjct: 613 EFKLGLMHGRLSQEEKDRVMLEFAEGRYDILVSTTVIEVGIDVPRANVMVIENPERFGLA 672 Query: 356 YIH----RIGRGGRFGRKGVAINMVTEEDKRTLR 385 +H R+GRGG+ + + V EE LR Sbjct: 673 QLHQLRGRVGRGGQEAYCFLVVGDVGEEAMERLR 706 >4CDG-A nrPDB Length = 673 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 76/355 (21%), Positives = 134/355 (37%), Gaps = 34/355 (9%) Query: 50 YGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPT 109 +G Q AI + G D +G GK S+ Q+ + +V++P Sbjct: 30 FGLHNFRTNQLEAINAALLGEDCFILMPTGGGK------SLCYQLPACVSPGVTVVISPL 83 Query: 110 REL-AQQIQKVV-------MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 161 R L Q+QK+ GD + + + + KL P I + R Sbjct: 84 RSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICAS-NR 142 Query: 162 VFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLN------SNTQVVLLSAT 215 + L Y K + FV+DEA +S+ D D ++++N + V+ L+AT Sbjct: 143 LISTLENLY-ERKLLARFVIDEA-HCVSQWGHDFRQD-YKRMNMLRQKFPSVPVMALTAT 199 Query: 216 ----MPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLT 271 + D+L K +R V ++ + + + ++ D L + + Sbjct: 200 ANPRVQKDILTQLK-----ILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHP 254 Query: 272 ITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREF-RSGSSRVLITTD 330 +I+ +RR+ D + + + A H + RD + +++ +V+ T Sbjct: 255 YDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATI 314 Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLR 385 GID V VI+ LP + E Y GR GR G + T D L+ Sbjct: 315 AFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLK 369 >5AGA-A nrPDB Length = 830 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 90/428 (21%), Positives = 173/428 (40%), Gaps = 111/428 (25%) Query: 36 DMNLSESLLRGIYAYGFEKPSAIQQRAIL--PCIKGYDVIAQAQSGTGKTATFAISILQQ 93 + L +++L +++G +K Q +L ++G +++ A + GKT + IL++ Sbjct: 9 NWGLPKAVLEKYHSFGVKKMFEWQAECLLLGQVLEGKNLVYSAPTSAGKTLVAELLILKR 68 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPH 153 + L+++ +AL + P +A++ + + +L +G +G T+ L Sbjct: 69 V-LEMR-KKALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSLD----- 121 Query: 154 IIVGTPGRVFDMLNRRYLSPK--YIKMFVLDEADEMLS---RGFKDQIY----------- 197 I V T R ++NR K + M V+DE ML RG+ ++ Sbjct: 122 IAVCTIERANGLINRLIEENKMDLLGMVVVDEL-HMLGDSHRGYLLELLLTKICYITRKS 180 Query: 198 -----DIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRD--------PIRILVKKE----- 239 D+ L++ Q+V +SAT+P+ LE+ ++ P+ +L + Sbjct: 181 ASCQADLASSLSNAVQIVGMSATLPN--LELVASWLNAELYHTDFRPVPLLESVKVGNSI 238 Query: 240 -ELTLEGIRQF--YINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH--- 293 + +++ +R+F + V+ +E + +LC YET+ +V+ +K W EK+ Sbjct: 239 YDSSMKLVREFEPMLQVKGDEDHVVSLC--YETICDNHSVLLFCPSKK--W-CEKLADII 293 Query: 294 ARDF--------------------------------------------------TVSAMH 303 AR+F V+ H Sbjct: 294 AREFYNLHHQAEGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHH 353 Query: 304 GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTNRENYIHR 359 + +ERD+I FR G RVL T L+ G+++ ++I + P + Y Sbjct: 354 AGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQM 413 Query: 360 IGRGGRFG 367 +GR GR G Sbjct: 414 VGRAGRKG 421 >6G19-A nrPDB Length = 696 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 14/105 (13%) Query: 273 TQAVIFINTRRKV----DWLTEKMHARDFTVSAMH----------GDMDQKERDVIMREF 318 ++ +IF TR+ W+ E + V A H M Q E+ ++ +F Sbjct: 395 SRGIIFTKTRQSTYALSQWIMENAKFAEVGVKAHHLIGAGHSSEVKPMTQTEQKEVISKF 454 Query: 319 RSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG 363 R+G +LI T + G+D+++ ++VI Y L TN + GR Sbjct: 455 RTGEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA 499 >2WWY-A nrPDB Length = 591 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 20/91 (21%), Positives = 45/91 (49%) Query: 275 AVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLAR 334 +I+ +++ + +T + A H +++ +++ + R++ + +V++ T Sbjct: 270 GIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGM 329 Query: 335 GIDVQQVSLVINYDLPTNRENYIHRIGRGGR 365 GID V VI++ + + ENY GR GR Sbjct: 330 GIDKPDVRFVIHHSMSKSMENYYQESGRAGR 360 >5LBA-B nrPDB Length = 445 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 20/93 (21%), Positives = 40/93 (43%) Query: 276 VIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARG 335 +++ TR + L ++ R A H + ER ++ ++ V++ T G Sbjct: 255 IVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMG 314 Query: 336 IDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR 368 +D V V ++++ + Y GR GR G+ Sbjct: 315 VDKANVRFVAHWNIAKSMAGYYQESGRAGRDGK 347 >5LB8-A nrPDB Length = 518 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 20/94 (21%), Positives = 40/94 (42%) Query: 275 AVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLAR 334 +++ TR + L ++ R A H + ER ++ ++ V++ T Sbjct: 254 GIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGM 313 Query: 335 GIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR 368 G+D V V ++++ + Y GR GR G+ Sbjct: 314 GVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGK 347 >5JCF-A nrPDB Length = 701 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 20/120 (16%) Query: 261 DTLCDLYETLTITQAVIFINTRRKV----DWLTE---------KMHARDFTVSAMHGD-- 305 +TL + + + +IF TR+ W+ + K H F + A H Sbjct: 388 NTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAH---FLIGAGHNSET 444 Query: 306 --MDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG 363 M Q E+ ++ +FR GS +LI T + G+D+++ ++VI Y L TN + GR Sbjct: 445 KPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA 504 >1D9Z-A nrPDB Length = 657 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 19/102 (18%) Query: 280 NTRRKVDWLTEKMHARDFT---------VSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330 N R V LT+KM A D T V+ +H ++ ER I+R+ R G VL+ + Sbjct: 444 NERTLVTTLTKKM-AEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGIN 502 Query: 331 LLARGIDVQQVSLVINYDLPTNRENY-------IHRIGRGGR 365 LL G+D+ +VSLV D ++E + I IGR R Sbjct: 503 LLREGLDIPEVSLVAILD--ADKEGFLRSERSLIQTIGRAAR 542 >1WP9-A nrPDB Length = 494 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 50/181 (27%), Positives = 84/181 (46%), Gaps = 30/181 (16%) Query: 226 KFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLY-ETLTITQ---AVIFINT 281 K M+ I +LV+ +E+ L+ K+D L ++ E L Q ++F N Sbjct: 323 KRMKKAISLLVQAKEIGLD------------HPKMDKLKEIIREQLQRKQNSKIIVFTNY 370 Query: 282 R---RKV--DWLTEKMHARDFTVSAMHGD---MDQKERDVIMREFRSGSSRVLITTDLLA 333 R +K+ + + + + A+ F A + + Q+E+ +I+ EF G VL+ T + Sbjct: 371 RETAKKIVNELVKDGIKAKRFVGQASKENDRGLSQREQKLILDEFARGEFNVLVATSVGE 430 Query: 334 RGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNT 393 G+DV +V LV+ Y+ + I R GR GR V I M + RD E +Y + Sbjct: 431 EGLDVPEVDLVVFYEPVPSAIRSIQRRGRTGRHMPGRVIILMA-----KGTRD-EAYYWS 484 Query: 394 S 394 S Sbjct: 485 S 485 >2NMV-A nrPDB Length = 661 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 37/108 (34%), Positives = 53/108 (49%), Gaps = 19/108 (17%) Query: 274 QAVIFINTRRKVDWLTEKMHARDFT---------VSAMHGDMDQKERDVIMREFRSGSSR 324 QA I N R V LT+KM + D T V+ +H ++ ER I+R+ R G Sbjct: 439 QARIERNERVLVTTLTKKM-SEDLTDYLKEIGIKVNYLHSEIKTLERIEIIRDLRLGKYD 497 Query: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENY-------IHRIGRGGR 365 VL+ +LL G+D+ +VSLV D ++E + I IGR R Sbjct: 498 VLVGINLLREGLDIPEVSLVAILD--ADKEGFLRSERSLIQTIGRAAR 543 >4A2W-A nrPDB Length = 936 Score = 41.2 bits (95), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Query: 320 SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTE- 378 S +R+LI T + GID+ Q +LV+ Y+ N I GRG G K + + TE Sbjct: 692 SKDNRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSKCILVTSKTEV 751 Query: 379 -EDKRTLRDIETFYNTSIEEM 398 E+++ R E N ++E++ Sbjct: 752 VENEKCNRYKEEMMNKAVEKI 772 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 53/212 (25%), Positives = 85/212 (40%), Gaps = 33/212 (15%) Query: 20 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAI---------QQRAILPCIKGY 70 E +E++ ++ D NLSE+L G A G KP + Q P I G Sbjct: 207 EDCLEASMTYSEEAEPDDNLSENL--GSAAEGIGKPPPVYETKKARSYQIELAQPAINGK 264 Query: 71 DVIAQAQSGTGKTATFAISIL------QQIELDLKATQALVLAPTRELAQQIQKVVMALG 124 + + A +G+GKT +SIL Q + KA + + LA + +Q + V Sbjct: 265 NALICAPTGSGKT---FVSILICEHHFQNMPAGRKA-KVVFLATKVPVYEQQKNVFKHHF 320 Query: 125 DYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYI-KMFVLDE 183 + G S G V+K+ +E IIV TP + + L+ I + + DE Sbjct: 321 ERQGYSVQGISGENFSNVSVEKV-IEDSDIIVVTPQILVNSFEDGTLTSLSIFTLMIFDE 379 Query: 184 ADEMLSRGFKDQIYDIF------QKLNSNTQV 209 + Y++ QK NS +Q+ Sbjct: 380 CHNTTG----NHPYNVLMTRYLEQKFNSASQL 407 >4A2Q-A nrPDB Length = 797 Score = 41.2 bits (95), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Query: 320 SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTE- 378 S +R+LI T + GID+ Q +LV+ Y+ N I GRG G K + + TE Sbjct: 692 SKDNRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSKCILVTSKTEV 751 Query: 379 -EDKRTLRDIETFYNTSIEEM 398 E+++ R E N ++E++ Sbjct: 752 VENEKCNRYKEEMMNKAVEKI 772 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 53/212 (25%), Positives = 85/212 (40%), Gaps = 33/212 (15%) Query: 20 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAI---------QQRAILPCIKGY 70 E +E++ ++ D NLSE+L G A G KP + Q P I G Sbjct: 207 EDCLEASMTYSEEAEPDDNLSENL--GSAAEGIGKPPPVYETKKARSYQIELAQPAINGK 264 Query: 71 DVIAQAQSGTGKTATFAISIL------QQIELDLKATQALVLAPTRELAQQIQKVVMALG 124 + + A +G+GKT +SIL Q + KA + + LA + +Q + V Sbjct: 265 NALICAPTGSGKT---FVSILICEHHFQNMPAGRKA-KVVFLATKVPVYEQQKNVFKHHF 320 Query: 125 DYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYI-KMFVLDE 183 + G S G V+K+ +E IIV TP + + L+ I + + DE Sbjct: 321 ERQGYSVQGISGENFSNVSVEKV-IEDSDIIVVTPQILVNSFEDGTLTSLSIFTLMIFDE 379 Query: 184 ADEMLSRGFKDQIYDIF------QKLNSNTQV 209 + Y++ QK NS +Q+ Sbjct: 380 CHNTTG----NHPYNVLMTRYLEQKFNSASQL 407 >5TNU-A nrPDB Length = 459 Score = 41.2 bits (95), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 18/69 (26%), Positives = 37/69 (53%) Query: 294 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 353 ++ F + + D+ ER+ I+++FR G RV++ + + G+DV +L I + Sbjct: 361 SKTFLIPVVTYKTDKDEREEILQKFRDGEYRVIVASTVFDEGVDVPDATLAIVMGGYGTK 420 Query: 354 ENYIHRIGR 362 ++ R+GR Sbjct: 421 RQFLQRLGR 429 >4A36-A nrPDB Length = 556 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Query: 320 SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTE- 378 S +R+LI T + GID+ Q +LV+ Y+ N I GRG G K + + TE Sbjct: 451 SKDNRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSKCILVTSKTEV 510 Query: 379 -EDKRTLRDIETFYNTSIEEM 398 E+++ R E N ++E++ Sbjct: 511 VENEKCNRYKEEMMNKAVEKI 531 >1C4O-A nrPDB Length = 664 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 19/135 (14%) Query: 274 QAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLA 333 + ++ + T R + LT + +H ++D +R ++R+ R G L+ +LL Sbjct: 441 RTLVTVLTVRMAEELTSFLVEHGIRARYLHHELDAFKRQALIRDLRLGHYDCLVGINLLR 500 Query: 334 RGIDVQQVSLVINYDLPTNRENY-------IHRIGRGGRFGRKGV---------AINMVT 377 G+D+ +VSLV D ++E + I IGR R R V A+ Sbjct: 501 EGLDIPEVSLVAILD--ADKEGFLRSERSLIQTIGRAARNARGEVWLYADRVSEAMQRAI 558 Query: 378 EEDKRTLRDIETFYN 392 EE R R ++ YN Sbjct: 559 EETNRR-RALQEAYN 572 >2FWR-A nrPDB Length = 472 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 36/66 (54%) Query: 297 FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENY 356 F + A+ ++ER+ I+ FR+G R ++++ +L GIDV ++ + + Y Sbjct: 369 FLIPAITHRTSREEREEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREY 428 Query: 357 IHRIGR 362 I R+GR Sbjct: 429 IQRLGR 434 >4ON9-A nrPDB Length = 580 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 38/131 (29%), Positives = 55/131 (41%), Gaps = 17/131 (12%) Query: 256 EEWKLDTLC----DLYETLTITQAVIFINTRRKVD----WL--TEKMHARDFTVSAMHGD 305 E KL+ LC + Y T ++F+ TR VD W+ K+ + G Sbjct: 394 ENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGK 453 Query: 306 MDQK------ERDVIMREFR-SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIH 358 +Q + I+ F+ SG +LI T + GID+ Q +LVI Y+ N I Sbjct: 454 TNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQ 513 Query: 359 RIGRGGRFGRK 369 GRG G K Sbjct: 514 TRGRGRARGSK 524 >3TBK-A nrPDB Length = 555 Score = 38.1 bits (87), Expect = 0.007, Method: Compositional matrix adjust. Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 13/104 (12%) Query: 273 TQAVIFINTRRKVD----WLTEKMHARDFTVSAMHG--------DMDQKERDVIMREFR- 319 T+ ++F+ TR VD W+ E + G M + ++ FR Sbjct: 390 TKTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGRTNRATGMTLPAQKCVLEAFRA 449 Query: 320 SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG 363 SG + +LI T + GID+ + +LVI Y+ N I GRG Sbjct: 450 SGDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGRG 493 >4BPB-A nrPDB Length = 698 Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust. Identities = 38/133 (28%), Positives = 53/133 (39%), Gaps = 19/133 (14%) Query: 256 EEWKLDTLCDL----YETLTITQAVIFINTRRKVD----WLTEK----------MHARDF 297 E KL+ LC + Y T ++F+ TR VD W+ + R Sbjct: 378 ENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGK 437 Query: 298 TVSAMHGDMDQKERDVIMREFR-SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENY 356 T M + I+ F+ SG +LI T + GID+ Q +LVI Y+ N Sbjct: 438 TNQNTFFGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKM 497 Query: 357 IHRIGRGGRFGRK 369 I GRG G K Sbjct: 498 IQTRGRGRARGSK 510 >5JBJ-A nrPDB Length = 680 Score = 36.2 bits (82), Expect = 0.026, Method: Compositional matrix adjust. Identities = 24/105 (22%), Positives = 47/105 (44%), Gaps = 14/105 (13%) Query: 273 TQAVIFINTRRK----VDWL--TEKMHARDFTVSAMHGD--------MDQKERDVIMREF 318 ++ ++F TR+ + WL T + + + + G M Q E+ ++ F Sbjct: 372 SRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLF 431 Query: 319 RSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG 363 R G +L +T + G+D+ + ++V+ Y L TN + GR Sbjct: 432 RYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRA 476 >6QKC-A nrPDB Length = 915 Score = 33.5 bits (75), Expect = 0.18, Method: Compositional matrix adjust. Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 5/83 (6%) Query: 219 DVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIF 278 +V++ +K FM I I++KK + + G+ F + E W +C ++ + ++ + Sbjct: 509 EVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW----MCIVFAYIGVSVVLFL 564 Query: 279 INTRRKVDWLTEKM-HARDFTVS 300 ++ +W +E+ RD T S Sbjct: 565 VSRFSPYEWHSEEFEEGRDQTTS 587 >2ZJ8-A nrPDB Length = 720 Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust. Identities = 91/413 (22%), Positives = 160/413 (38%), Gaps = 91/413 (22%) Query: 35 DDMNLSESLLRGIYAYGFEKPSAIQQRAILPCI-KGYDVIAQAQSGTGKTATFAISILQQ 93 D++ + E + + G E Q A+ I +G + + + +GKT I+++ + Sbjct: 4 DELRVDERIKSTLKERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAMVHR 63 Query: 94 IELDLKATQALVLAPTRELA----QQIQ-------KVVMALGDYMGASCHACIGGTNVRA 142 I + +A+ + P + LA Q+ Q +V MA GDY S +G + Sbjct: 64 ILT--QGGKAVYIVPLKALAEEKFQEFQDWEKIGLRVAMATGDY--DSKDEWLGKYD--- 116 Query: 143 EVQKLQMEAPHIIVGTPGRVFDMLNRRYLSP-KYIKMFVLDEADEMLSRGFKDQIYDIFQ 201 II+ T + FD L R S K +K+ V DE + SR + I Sbjct: 117 -----------IIIATAEK-FDSLLRHGSSWIKDVKILVADEIHLIGSRDRGATLEVILA 164 Query: 202 KLNSNTQVVLLSATM--PSDVLE-VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEW 258 + Q++ LSAT+ P ++ E + + + R + + + +G V E+ Sbjct: 165 HMLGKAQIIGLSATIGNPEELAEWLNAELIVSDWRPVKLRRGVFYQGF------VTWEDG 218 Query: 259 KLDTLCD----LYETLTITQ-AVIFINTRR-----------KVDWLTEKMHARDFT---- 298 +D +Y+ + + A+IF+N RR KV L K R Sbjct: 219 SIDRFSSWEELVYDAIRKKKGALIFVNMRRKAERVALELSKKVKSLLTKPEIRALNELAD 278 Query: 299 ------------------VSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQ 340 V+ H + + ER ++ FR G + ++ T L+ GI+ Sbjct: 279 SLEENPTNEKLAKAIRGGVAFHHAGLGRDERVLVEENFRKGIIKAVVATPTLSAGINTPA 338 Query: 341 VSLVINYDLPTNRENYIHRI---------GRGGR--FGRKGVAINMVTEEDKR 382 ++I D+ + + RI GR GR + G I + T +D R Sbjct: 339 FRVIIR-DIWRYSDFGMERIPIIEVHQMLGRAGRPKYDEVGEGIIVSTSDDPR 390 >3TF5-A nrPDB Length = 493 Score = 32.3 bits (72), Expect = 0.43, Method: Compositional matrix adjust. Identities = 59/259 (22%), Positives = 101/259 (38%), Gaps = 57/259 (22%) Query: 154 IIVGTPGRVFDMLNRRYLSPKYIKM-------------FVLDEADEMLSRGFKDQIYDIF 200 I V TP + + M R KYI+ V +++ + + +I+D Sbjct: 87 ISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTPVRAAESIRRIFDAN 146 Query: 201 QKLNSNTQVVLLSATMPSDVLEVTK-KFMRDPIRILVKKEELTLEGIRQFYINVEREEWK 259 K N N QV+ + P + E T K +++P R+L+ +E T EG R Sbjct: 147 TKPNLNLQVL----SNPEFLAEGTAIKDLKNPDRVLIGGDE-TPEGQRA----------- 190 Query: 260 LDTLCDLYETLTITQAVIFINTRRKVDWLTE--KMHARDFTVSAMHGDMDQKERDVIMRE 317 + LC +YE + ++ NT W +E K+ A F + Sbjct: 191 VQALCAVYEHWVPREKILTTNT-----WSSELSKLAANAFLAQRI--------------- 230 Query: 318 FRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVT 377 SS I+ A G DV++V+ I D + +G GG +K V +N+V Sbjct: 231 ----SSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDV-LNLVY 285 Query: 378 EEDKRTLRDIETFYNTSIE 396 + L ++ ++ I+ Sbjct: 286 LCEALNLPEVARYWQQVID 304 >6BOG-A nrPDB Length = 968 Score = 31.6 bits (70), Expect = 0.73, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 2/72 (2%) Query: 299 VSAMHGDMDQKERDVIMREF--RSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENY 356 + H M ERD F ++VL+ +++ + G + Q S ++ +DLP N + Sbjct: 531 AAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLL 590 Query: 357 IHRIGRGGRFGR 368 RIGR R G+ Sbjct: 591 EQRIGRLDRIGQ 602 >2VA8-A nrPDB Length = 715 Score = 31.2 bits (69), Expect = 0.78, Method: Compositional matrix adjust. Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 11/94 (11%) Query: 299 VSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRE---- 354 V+ H + + RD+I FR +V++ T LA G+++ +++I N++ Sbjct: 315 VAYHHAGLSKALRDLIEEGFRQRKIKVIVATPTLAAGVNLPARTVIIGDIYRFNKKIAGY 374 Query: 355 -------NYIHRIGRGGRFGRKGVAINMVTEEDK 381 Y GR GR G + ++V DK Sbjct: 375 YDEIPIMEYKQMSGRAGRPGFDQIGESIVVVRDK 408 >3AX1-A nrPDB Length = 358 Score = 31.2 bits (69), Expect = 0.84, Method: Compositional matrix adjust. Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 21/127 (16%) Query: 273 TQAVIFINTRRKVDWLTEKMHARD-FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDL 331 TQ F NT ++ DWL K H + +V D+ QK + + +SG T DL Sbjct: 35 TQKRAFFNTHKEEDWLKNKYHPTNLLSVIERRNDLAQKVAKDFLLDLQSG------TLDL 88 Query: 332 LARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV----------TEEDK 381 G V ++ P N E+ +G+ R G G N + T + K Sbjct: 89 ---GPAVTALNKSGRTSEP-NSEDEAAGVGKRKRHGMGGAKENELLSAAPKAPSFTSDPK 144 Query: 382 RTLRDIE 388 R L D+E Sbjct: 145 RILTDVE 151 >6BYQ-A nrPDB Length = 410 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 63 ILPCIKGYDVIAQAQ----SGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 118 + P ++GYD +A G + + Q L Q+++ P E +QK Sbjct: 181 LYPLLQGYDSVAMGADIELGGNDQKFNLLVGRFLQRAYGLNKEQSIITMPLLEGLDGVQK 240 Query: 119 VVMALGDYMG 128 + +LG+Y+G Sbjct: 241 MSKSLGNYVG 250 >5V8F-E nrPDB Length = 479 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 35/140 (25%), Positives = 56/140 (40%), Gaps = 12/140 (8%) Query: 65 PCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALG 124 P I ++I Q SGTGKT T L + + L + L Q I + V Sbjct: 26 PDITPSNLILQGYSGTGKTYTLKKYFNANPNLHAVWLEPVELVSWKPLLQAIARTV---- 81 Query: 125 DYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEA 184 Y + + I T + LQ+E P ++V T +F + L K +LD Sbjct: 82 QYKLKTLYPNIPTT----DYDPLQVEEPFLLVKTLHNIF--VQYESLQEKTCLFLILDGF 135 Query: 185 DEMLSRGFKDQIYDIFQKLN 204 D + + +++ + KLN Sbjct: 136 DSL--QDLDAALFNKYIKLN 153 >6DCR-A nrPDB Length = 694 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 12/68 (17%) Query: 315 MREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTN------------RENYIHRIGR 362 + E G +R+LI T +LA+G V+LV D+ + Y GR Sbjct: 487 LAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSADFRSAERFAQLYTQVAGR 546 Query: 363 GGRFGRKG 370 GR G++G Sbjct: 547 AGRAGKQG 554 >5IDF-B nrPDB Length = 874 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 15/72 (20%), Positives = 35/72 (48%), Gaps = 4/72 (5%) Query: 219 DVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIF 278 +V++ +K FM I I++KK + + G+ F + E W +C ++ + ++ + Sbjct: 497 EVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW----MCIVFAYIGVSVVLFL 552 Query: 279 INTRRKVDWLTE 290 ++ +W E Sbjct: 553 VSRFSPYEWHLE 564 >4IE5-A nrPDB Length = 495 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 12/107 (11%) Query: 109 TRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR 168 + EL +++Q+ + L H C+ VR + + L I++G PG + LN Sbjct: 48 SEELHKEVQEAFLTLHK------HGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNT 101 Query: 169 RYLS-PKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSA 214 R + P +K + + ++ + F KLN Q+ + A Sbjct: 102 RLFTVPWPVKGSNIKHTEAEIAAAC-----ETFLKLNDYLQIETIQA 143 >5JXT-B nrPDB Length = 349 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 273 TQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREF-RSGSSRV--LITT 329 ++ +IF R +D L + R + + G ++R + E+ + GS + L+TT Sbjct: 102 SRVLIFSQMSRLLDILEDYCVFRGYKYCRIDGSTAHEDRIAAIDEYNKPGSDKFIFLLTT 161 Query: 330 DLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR 368 GI++ +VI YD N + + + R R G+ Sbjct: 162 RAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQ 200 >4WTS-A nrPDB Length = 298 Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust. Identities = 13/25 (52%), Positives = 16/25 (64%) Query: 80 TGKTATFAISILQQIELDLKATQAL 104 T + TFA+S+ Q L L ATQAL Sbjct: 66 TNRVRTFALSVCNQASLALAATQAL 90 >4NL8-A nrPDB Length = 747 Score = 28.5 bits (62), Expect = 5.4, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 34/85 (40%), Gaps = 16/85 (18%) Query: 305 DMDQKERDVIMREF----RSGSSRVLITTDLLARGIDVQQVSLVINYDLPTN-------- 352 D D R + E G +R+LI T +LA+G V+LV D+ Sbjct: 526 DRDTTSRKGALEEHLAAVHRGGARILIGTQMLAKGHHFPDVTLVSLLDVDGALFSADFRS 585 Query: 353 ----RENYIHRIGRGGRFGRKGVAI 373 + Y GR GR G++G I Sbjct: 586 AERFAQLYTQVSGRAGRAGKQGEVI 610 >5JXR-A nrPDB Length = 723 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 273 TQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREF-RSGSSRV--LITT 329 ++ +IF R +D L + R + + G ++R + E+ + GS + L+TT Sbjct: 427 SRVLIFSQMSRLLDILEDYCVFRGYKYCRIDGSTAHEDRIAAIDEYNKPGSDKFIFLLTT 486 Query: 330 DLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR 368 GI++ +VI YD N + + + R R G+ Sbjct: 487 RAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQ 525 >6BQZ-A nrPDB Length = 408 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 50 YGFEKPSAIQQRAILPCIKGYDVIA-QAQSGTGKT-ATFAISILQQIELDL-KATQALVL 106 Y +P AI + + P ++GYD IA +A G T TF + + + ++ + +Q + Sbjct: 163 YNNHQPIAIHE-FLYPLVQGYDSIALEADVELGGTDQTFNLLMGRTLQSRYGQESQVCIT 221 Query: 107 APTRELAQQIQKVVMALGDYMG 128 P E + K+ +LG+Y+G Sbjct: 222 VPILEGLDGVNKMSKSLGNYIG 243 >6FNP-B nrPDB Length = 300 Score = 28.1 bits (61), Expect = 6.6, Method: Compositional matrix adjust. Identities = 24/104 (23%), Positives = 40/104 (38%), Gaps = 26/104 (25%) Query: 112 LAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYL 171 +AQ + V MA DY + GG R + + P +I+ Sbjct: 142 VAQAVADVGMA--DYADSEPSNLSGGQKQRVAIAGILAVKPQVII--------------- 184 Query: 172 SPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSAT 215 LDE+ ML K+QI D+ +K+ + + ++S T Sbjct: 185 ---------LDESTSMLDPEGKEQILDLVRKIKEDNNLTVISIT 219 >4U1Y-A nrPDB Length = 819 Score = 28.1 bits (61), Expect = 7.1, Method: Compositional matrix adjust. Identities = 15/74 (20%), Positives = 36/74 (48%), Gaps = 4/74 (5%) Query: 219 DVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIF 278 +V++ +K FM I I++KK + + G+ F + E W + ++ + ++ + Sbjct: 480 EVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW----MAIVFAYILVSVVLFL 535 Query: 279 INTRRKVDWLTEKM 292 ++ +W TE+ Sbjct: 536 VSRFSPYEWHTEEF 549 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3EIQ-A nrPDB 571 e-163 2HYI-C nrPDB 522 e-149 2VSX-A nrPDB 460 e-130 4BRW-A nrPDB 446 e-126 5ANR-B nrPDB 439 e-123 6CZ5-A nrPDB 433 e-122 4NHO-A nrPDB 432 e-121 5IVL-B nrPDB 430 e-121 2I4I-A nrPDB 427 e-120 3JCR-F nrPDB 425 e-119 1XTI-A nrPDB 422 e-118 4D25-A nrPDB 418 e-117 2DB3-A nrPDB 410 e-115 6B4I-E nrPDB 409 e-114 5DTU-A nrPDB 407 e-114 1HV8-A nrPDB 405 e-113 5SUQ-A nrPDB 403 e-113 5SUP-A nrPDB 400 e-112 3PEW-A nrPDB 396 e-110 6CB1-p nrPDB 379 e-105 4KBG-A nrPDB 361 e-100 3FHO-A nrPDB 361 e-100 4LJY-A nrPDB 354 4e-98 5ZWN-y nrPDB 352 2e-97 4W7S-A nrPDB 351 4e-97 2Z0M-A nrPDB 339 2e-93 3SQW-A nrPDB 324 5e-89 3I62-A nrPDB 321 4e-88 5ZBZ-A nrPDB 311 3e-85 3BOR-A nrPDB 310 7e-85 4CDG-A nrPDB 279 2e-75 1QVA-A nrPDB 273 7e-74 1WRB-A nrPDB 266 9e-72 4PX9-A nrPDB 264 5e-71 6CRM-A nrPDB 263 8e-71 3FE2-A nrPDB 256 2e-68 5GJU-A nrPDB 255 3e-68 1T6N-A nrPDB 254 7e-68 5LST-A nrPDB 251 5e-67 1OYY-A nrPDB 248 3e-66 1VEC-A nrPDB 246 1e-65 2GXQ-A nrPDB 245 2e-65 5H1Y-A nrPDB 244 7e-65 5GVS-A nrPDB 239 2e-63 3BER-A nrPDB 239 2e-63 6AIC-A nrPDB 238 3e-63 3LY5-A nrPDB 237 7e-63 3FMO-B nrPDB 234 5e-62 3FHC-B nrPDB 234 6e-62 3IUY-A nrPDB 228 4e-60 2KBE-A nrPDB 226 2e-59 1Q0U-A nrPDB 222 2e-58 2PL3-A nrPDB 222 2e-58 2OXC-A nrPDB 219 2e-57 5V9X-A nrPDB 213 1e-55 3DKP-A nrPDB 210 7e-55 4Q48-A nrPDB 209 2e-54 5LBA-B nrPDB 203 1e-52 5LB8-A nrPDB 203 1e-52 2WWY-A nrPDB 202 3e-52 5AGA-A nrPDB 197 7e-51 1GM5-A nrPDB 132 2e-31 1WP9-A nrPDB 110 1e-24 5TNU-A nrPDB 101 4e-22 6G19-A nrPDB 100 1e-21 4GL2-A nrPDB 98 9e-21 5JCF-A nrPDB 97 1e-20 1D9Z-A nrPDB 95 7e-20 4A2W-A nrPDB 93 2e-19 4A2Q-A nrPDB 92 4e-19 4A36-A nrPDB 92 6e-19 2NMV-A nrPDB 89 3e-18 Sequences not found previously or not previously below threshold: 2P6R-A nrPDB 139 2e-33 2ZJ8-A nrPDB 129 2e-30 2VA8-A nrPDB 127 7e-30 6C90-A nrPDB 89 4e-18 5JBJ-A nrPDB 85 6e-17 3TBK-A nrPDB 85 8e-17 3P4X-A nrPDB 83 1e-16 2FWR-A nrPDB 83 3e-16 4ON9-A nrPDB 82 6e-16 4BPB-A nrPDB 82 7e-16 1C4O-A nrPDB 81 8e-16 6DCR-A nrPDB 78 5e-15 4XGT-A nrPDB 75 6e-14 6HEG-A nrPDB 72 7e-13 4NL8-A nrPDB 71 1e-12 5VHD-D nrPDB 70 2e-12 4A4Z-A nrPDB 68 1e-11 2OCA-A nrPDB 67 1e-11 6F4A-B nrPDB 67 1e-11 5WX1-A nrPDB 62 5e-10 5WSO-A nrPDB 61 9e-10 5N8S-A nrPDB 60 2e-09 5D0U-A nrPDB 60 2e-09 4CBI-A nrPDB 59 3e-09 5I8Q-A nrPDB 59 4e-09 5GM6-Y nrPDB 58 5e-09 6BOG-A nrPDB 58 7e-09 5FMF-1 nrPDB 57 1e-08 6I3O-A nrPDB 57 1e-08 5SVA-Z nrPDB 57 1e-08 3B6E-A nrPDB 56 3e-08 3RC8-A nrPDB 53 2e-07 3MWY-W nrPDB 53 3e-07 6ID1-V nrPDB 52 3e-07 3H1T-A nrPDB 52 3e-07 6FA9-A nrPDB 52 4e-07 6FTX-W nrPDB 52 4e-07 5K8T-A nrPDB 52 6e-07 3DIN-A nrPDB 52 6e-07 5XDR-A nrPDB 51 9e-07 5JXR-A nrPDB 51 1e-06 4OK6-A nrPDB 51 1e-06 5JXT-B nrPDB 51 1e-06 4B6E-A nrPDB 51 1e-06 2ZJO-A nrPDB 50 2e-06 2BMF-A nrPDB 50 2e-06 2QEQ-A nrPDB 50 2e-06 2Z83-A nrPDB 48 6e-06 5X0Y-O nrPDB 48 7e-06 2JLW-A nrPDB 48 8e-06 4UAQ-A nrPDB 48 9e-06 2WZQ-A nrPDB 47 1e-05 5HZR-A nrPDB 47 1e-05 1YKS-A nrPDB 47 1e-05 2V6J-A nrPDB 47 1e-05 2WV9-A nrPDB 47 2e-05 2V8O-A nrPDB 47 2e-05 5OQJ-7 nrPDB 46 3e-05 1RIF-A nrPDB 44 1e-04 5WDX-A nrPDB 43 2e-04 3BXZ-A nrPDB 43 2e-04 5GN1-A nrPDB 41 8e-04 1Z6A-A nrPDB 41 9e-04 1Z5Z-A nrPDB 41 0.001 1TF2-A nrPDB 41 0.001 5EUL-A nrPDB 41 0.001 4QQW-A nrPDB 40 0.002 2FZ4-A nrPDB 39 0.004 6FWS-A nrPDB 38 0.006 3LLM-A nrPDB 38 0.008 6EG3-A nrPDB 37 0.013 5H8W-A nrPDB 37 0.014 1Z3I-X nrPDB 37 0.016 1NLZ-A nrPDB 35 0.045 5K9T-A nrPDB 35 0.046 3A2B-A nrPDB 35 0.051 2FSI-A nrPDB 35 0.072 1NL3-A nrPDB 35 0.090 5FL3-A nrPDB 33 0.20 1EJE-A nrPDB 33 0.25 4B3F-X nrPDB 33 0.27 2V1U-A nrPDB 31 0.89 4ZCF-C nrPDB 31 0.92 1UB3-A nrPDB 31 0.95 3CRV-A nrPDB 31 1.2 1SXJ-C nrPDB 31 1.3 5O6D-A nrPDB 30 1.4 4LRY-C nrPDB 30 2.6 4HZU-A nrPDB 29 3.1 4XRF-A nrPDB 29 3.3 4B4H-A nrPDB 29 3.6 4ZWB-A nrPDB 29 3.7 6D00-1 nrPDB 29 3.9 3J7Y-f nrPDB 29 4.2 2Q6T-A nrPDB 29 4.4 4H1G-A nrPDB 29 4.5 6FES-A nrPDB 29 4.6 2Y4N-A nrPDB 29 4.7 6F5D-G nrPDB 29 4.9 3ACB-A nrPDB 28 5.4 2JGA-A nrPDB 28 5.5 4U00-A nrPDB 28 5.8 1Z7N-E nrPDB 28 6.0 1D5A-A nrPDB 28 8.4 >3EIQ-A nrPDB Length = 414 Score = 571 bits (1473), Expect = e-163, Method: Composition-based stats. Identities = 406/406 (100%), Positives = 406/406 (100%) Query: 1 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 60 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ Sbjct: 9 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 68 Query: 61 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 120 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV Sbjct: 69 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 128 Query: 121 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 180 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV Sbjct: 129 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 188 Query: 181 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE Sbjct: 189 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 248 Query: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 300 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS Sbjct: 249 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 308 Query: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI Sbjct: 309 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 368 Query: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI Sbjct: 369 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 414 >2HYI-C nrPDB Length = 413 Score = 522 bits (1346), Expect = e-149, Method: Composition-based stats. Identities = 271/406 (66%), Positives = 328/406 (80%), Gaps = 1/406 (0%) Query: 1 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 60 M+ S +R R + M S ++ +FD M L E LLRGIYAYGFEKPSAIQQ Sbjct: 7 MATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQ 66 Query: 61 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 120 RAI IKG DVIAQ+QSGTGKTATF+IS+LQ +++ ++ TQAL+LAPTRELA QIQK + Sbjct: 67 RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126 Query: 121 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 180 +ALGDYM CHACIGGTNV +++KL H++ GTPGRVFDM+ RR L + IKM V Sbjct: 127 LALGDYMNVQCHACIGGTNVGEDIRKLDY-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLV 185 Query: 181 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240 LDEADEML++GFK+QIYD+++ L TQVVL+SAT+P ++LE+T KFM DPIRILVK++E Sbjct: 186 LDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDE 245 Query: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 300 LTLEGI+QF++ VEREEWK DTLCDLY+TLTITQAVIF NT+RKVDWLTEKM +FTVS Sbjct: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVS 305 Query: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360 +MHGDM QKER+ IM+EFRSG+SRVLI+TD+ ARG+DV QVSL+INYDLP NRE YIHRI Sbjct: 306 SMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI 365 Query: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406 GR GR+GRKGVAIN V +D R LRDIE +Y+T I+EMP+NVADLI Sbjct: 366 GRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411 >2VSX-A nrPDB Length = 395 Score = 460 bits (1183), Expect = e-130, Method: Composition-based stats. Identities = 257/390 (65%), Positives = 317/390 (81%), Gaps = 2/390 (0%) Query: 17 MEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQA 76 E I++N++++V FDDM L E+LLRG++ YGFE+PSAIQQRAI+P I+G+DV+AQA Sbjct: 7 DIEESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQA 66 Query: 77 QSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIG 136 QSGTGKT TF+I+ LQ+I+ +KA QAL+LAPTRELA QIQKVVMAL +M HACIG Sbjct: 67 QSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIG 126 Query: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 196 GT+ + + L+ I+VGTPGRVFD + RR IKMF+LDEADEMLS GFK+QI Sbjct: 127 GTSFVEDAEGLR--DAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQI 184 Query: 197 YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVERE 256 Y IF L TQVVLLSATMP+DVLEVT KFMR+P+RILVKK+ELTLEGI+QFY+NVE E Sbjct: 185 YQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEE 244 Query: 257 EWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMR 316 E+K + L DLY+++++TQAVIF NTRRKV+ LT K+ FTVSA++ D+ Q+ERD IM+ Sbjct: 245 EYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMK 304 Query: 317 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV 376 EFRSGSSR+LI+TDLLARGIDVQQVSLVINYDLP N+ENYIHRIGRGGRFGRKGVAIN V Sbjct: 305 EFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFV 364 Query: 377 TEEDKRTLRDIETFYNTSIEEMPLNVADLI 406 T ED +R++E FY+T IEE+P ++A L+ Sbjct: 365 TNEDVGAMRELEKFYSTQIEELPSDIATLL 394 >4BRW-A nrPDB Length = 377 Score = 446 bits (1147), Expect = e-126, Method: Composition-based stats. Identities = 165/371 (44%), Positives = 225/371 (60%), Gaps = 3/371 (0%) Query: 32 DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL 91 ++F+D L LL GI+ GFEKPS IQ+ AI I G D++A+A++GTGKTA F I L Sbjct: 1 NTFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTL 60 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEA 151 ++++ L QAL++ PTRELA Q +VV LG + G SC GGTN+R ++ +L E Sbjct: 61 EKVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHCGISCMVTTGGTNLRDDILRLN-ET 119 Query: 152 PHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL 211 HI+VGTPGRV D+ +R+ +F++DEAD+MLSR FK I I L Q +L Sbjct: 120 VHILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLPPTHQSLL 179 Query: 212 LSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLT 271 SAT P V E K + P I + EELTL+GI Q+Y VE E KL L L+ L Sbjct: 180 FSATFPLTVDEFMDKHLHKPYEINLM-EELTLKGITQYYAFVE-ERQKLHCLNTLFSKLQ 237 Query: 272 ITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDL 331 I QA+IF N+ +V+ L +K+ ++ H M Q+ER+ + EFR G R L+ +DL Sbjct: 238 INQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRTLVCSDL 297 Query: 332 LARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFY 391 L RGID+Q V++VIN+D P E Y+HRIGR GRFG G+AIN++ D+ L IE Sbjct: 298 LTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINWNDRFNLYKIEQEL 357 Query: 392 NTSIEEMPLNV 402 T I +P + Sbjct: 358 GTEIAAIPATI 368 >5ANR-B nrPDB Length = 378 Score = 439 bits (1128), Expect = e-123, Method: Composition-based stats. Identities = 144/372 (38%), Positives = 232/372 (62%), Gaps = 4/372 (1%) Query: 32 DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL 91 + F+D L LL GI+ G+EKPS IQ+ +I + G D++A+A++GTGK+ + I +L Sbjct: 5 NEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL 64 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQME 150 ++++L QA+V+ PTRELA Q+ ++ + + +M GA A GGTN+R ++ +L + Sbjct: 65 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLD-D 123 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV 210 H+++ TPGR+ D++ + +++M VLDEAD++LS+ F + DI L N Q++ Sbjct: 124 TVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQIL 183 Query: 211 LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 270 L SAT P V + ++ P I + EELTL+G+ Q+Y V E K+ L L+ L Sbjct: 184 LYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHCLNTLFSRL 241 Query: 271 TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330 I Q++IF N+ ++V+ L +K+ ++ +H M Q+ R+ + +FR+G R L+ TD Sbjct: 242 QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 301 Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETF 390 L RGID+Q V++VIN+D P E Y+HRIGR GRFG G+AIN++T +D+ L+ IE Sbjct: 302 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 361 Query: 391 YNTSIEEMPLNV 402 T I+ +P N+ Sbjct: 362 LGTEIKPIPSNI 373 >6CZ5-A nrPDB Length = 480 Score = 433 bits (1113), Expect = e-122, Method: Composition-based stats. Identities = 123/412 (29%), Positives = 210/412 (50%), Gaps = 23/412 (5%) Query: 16 GMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQ 75 P +N ++SF D+ + E ++ I + +P+ +Q+ AI + D++A Sbjct: 37 DDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMAC 96 Query: 76 AQSGTGKTATFAISILQQIELD------------------LKATQALVLAPTRELAQQIQ 117 AQ+G GKTA F + IL QI D + +LVLAPTRELA QI Sbjct: 97 AQTGCGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIY 156 Query: 118 KVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIK 177 + GG ++ +++ L+ H++V TPGR+ DM+ R + + K Sbjct: 157 EEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGCHLLVATPGRLVDMMERGKIGLDFCK 215 Query: 178 MFVLDEADEMLSRGFKDQIYDIFQK--LNSN--TQVVLLSATMPSDVLEVTKKFMRDPIR 233 VLDEAD ML GF+ QI I ++ + ++ SAT P ++ + + F+ + I Sbjct: 216 YLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIF 275 Query: 234 ILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH 293 + V + T E I Q + VE + + L L T + ++F+ T++ D L + ++ Sbjct: 276 LAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLY 335 Query: 294 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 353 + +++HGD Q++R+ + +FRSG S +L+ T + ARG+D+ V VIN+DLP++ Sbjct: 336 HEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDI 395 Query: 354 ENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADL 405 E Y+HRIGR GR G G+A + E + +D+ + +E+P + ++ Sbjct: 396 EEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENM 447 >4NHO-A nrPDB Length = 488 Score = 432 bits (1112), Expect = e-121, Method: Composition-based stats. Identities = 124/417 (29%), Positives = 207/417 (49%), Gaps = 38/417 (9%) Query: 24 ESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKT 83 + S+ D +L +L I G+++P+ IQ++AI ++ D+I A++G+GKT Sbjct: 51 GGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKT 110 Query: 84 ATFAISIL---------QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHAC 134 A F I +L +IE + A++LAPTRELAQQI++ + G +G A Sbjct: 111 AAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAV 170 Query: 135 IGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKD 194 IGG + + +L+M I++ TPGR+ D+L RYL VLDEAD M+ GF+ Sbjct: 171 IGGISREDQGFRLRM-GCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEP 229 Query: 195 QIYDIFQKLN--------------------------SNTQVVLLSATMPSDVLEVTKKFM 228 + I + + Q V+ +ATMP V + + ++ Sbjct: 230 DVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYL 289 Query: 229 RDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWL 288 R P + + E + Q + + E K L + E +IF+N ++ D L Sbjct: 290 RRPAVVYIGSAGKPHERVEQK-VFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVL 348 Query: 289 TEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYD 348 + + + +HG Q++R+ + ++G+ +L+ TD+ RGID+Q VS+V+NYD Sbjct: 349 AKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYD 408 Query: 349 LPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI-ETFYNTSIEEMPLNVAD 404 + N E+YIHRIGR GR G+ GVAI +T+ED ++ + + + P +A+ Sbjct: 409 MAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELAN 465 >5IVL-B nrPDB Length = 429 Score = 430 bits (1106), Expect = e-121, Method: Composition-based stats. Identities = 140/370 (37%), Positives = 227/370 (61%), Gaps = 2/370 (0%) Query: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90 + +F ++ LS+ +++ I GFE+ + IQ + I ++ DVI QAQ+GTGKTA F I I Sbjct: 1 MTTFQELGLSQEVMKAIERMGFEETTPIQAKTIPLSLQNKDVIGQAQTGTGKTAAFGIPI 60 Query: 91 LQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQME 150 ++++++ A QALV+APTRELA Q+ + + +G GG ++ +++ L+ + Sbjct: 61 VEKVDVKNGAIQALVVAPTRELAIQVSEELYKIGAVKRVRVLPIYGGQDIERQIRALK-K 119 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV 210 PH+IVGTPGR+ D +NR L +++ VLDEADEML+ GF + I I + + Q + Sbjct: 120 HPHVIVGTPGRIIDHINRGTLRLEHVHTVVLDEADEMLNMGFIEDIEAILSHVPAERQTL 179 Query: 211 LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 270 L SATMP + + ++FM +P + VK +E+T+ I+Q+Y+ V E+ K D L L + Sbjct: 180 LFSATMPDPIRRIAERFMNEPELVKVKAKEMTVPNIQQYYLEVH-EKKKFDILTRLLDIQ 238 Query: 271 TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330 A++F T+R+VD L E ++ R + +HGD+ Q +R ++R+F+ G+ +L+ TD Sbjct: 239 APELAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLSQAKRLSVLRKFKEGAIEILVATD 298 Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETF 390 + ARG+D+ V+ V N+D+P + E+Y+HRIGR GR G+ GVA+ VT + L IE Sbjct: 299 VAARGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGKTGVAMTFVTPREIGQLHHIERT 358 Query: 391 YNTSIEEMPL 400 +E M Sbjct: 359 TKRKMERMKP 368 >2I4I-A nrPDB Length = 417 Score = 427 bits (1099), Expect = e-120, Method: Composition-based stats. Identities = 122/408 (29%), Positives = 210/408 (51%), Gaps = 23/408 (5%) Query: 20 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG 79 +N ++SF D+ + E ++ I + +P+ +Q+ AI + D++A AQ+G Sbjct: 3 VEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTG 62 Query: 80 TGKTATFAISILQQIELD------------------LKATQALVLAPTRELAQQIQKVVM 121 +GKTA F + IL QI D + +LVLAPTRELA QI + Sbjct: 63 SGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEAR 122 Query: 122 ALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVL 181 GG ++ +++ L+ H++V TPGR+ DM+ R + + K VL Sbjct: 123 KFSYRSRVRPCVVYGGADIGQQIRDLE-RGCHLLVATPGRLVDMMERGKIGLDFCKYLVL 181 Query: 182 DEADEMLSRGFKDQIYDIFQK--LNSN--TQVVLLSATMPSDVLEVTKKFMRDPIRILVK 237 DEAD ML GF+ QI I ++ + ++ SAT P ++ + + F+ + I + V Sbjct: 182 DEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVG 241 Query: 238 KEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDF 297 + T E I Q + VE + + L L T + ++F+ T++ D L + ++ + Sbjct: 242 RVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGY 301 Query: 298 TVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYI 357 +++HGD Q++R+ + +FRSG S +L+ T + ARG+D+ V VIN+DLP++ E Y+ Sbjct: 302 ACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYV 361 Query: 358 HRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADL 405 HRIGR GR G G+A + E + +D+ + +E+P + ++ Sbjct: 362 HRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENM 409 >3JCR-F nrPDB Length = 820 Score = 425 bits (1092), Expect = e-119, Method: Composition-based stats. Identities = 124/417 (29%), Positives = 207/417 (49%), Gaps = 38/417 (9%) Query: 24 ESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKT 83 + S+ D +L +L I G+++P+ IQ++AI ++ D+I A++G+GKT Sbjct: 383 GGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKT 442 Query: 84 ATFAISIL---------QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHAC 134 A F I +L +IE + A++LAPTRELAQQI++ + G +G A Sbjct: 443 AAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAV 502 Query: 135 IGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKD 194 IGG + + +L+M I++ TPGR+ D+L RYL VLDEAD M+ GF+ Sbjct: 503 IGGISREDQGFRLRM-GCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEP 561 Query: 195 QIYDIFQKLN--------------------------SNTQVVLLSATMPSDVLEVTKKFM 228 + I + + Q V+ +ATMP V + + ++ Sbjct: 562 DVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYL 621 Query: 229 RDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWL 288 R P + + E + Q + + E K L + E +IF+N ++ D L Sbjct: 622 RRPAVVYIGSAGKPHERVEQK-VFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVL 680 Query: 289 TEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYD 348 + + + +HG Q++R+ + ++G+ +L+ TD+ RGID+Q VS+V+NYD Sbjct: 681 AKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYD 740 Query: 349 LPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI-ETFYNTSIEEMPLNVAD 404 + N E+YIHRIGR GR G+ GVAI +T+ED ++ + + + P +A+ Sbjct: 741 MAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELAN 797 >1XTI-A nrPDB Length = 391 Score = 422 bits (1085), Expect = e-118, Method: Composition-based stats. Identities = 139/373 (37%), Positives = 218/373 (58%), Gaps = 5/373 (1%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F D L LLR I GFE PS +Q I I G DV+ QA+SG GKTA F ++ LQQ Sbjct: 10 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 69 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAP 152 +E LV+ TRELA QI K YM GG +++ + + L+ P Sbjct: 70 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 129 Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQVVL 211 HI+VGTPGR+ + + L+ K+IK F+LDE D+ML + + + +IF+ QV++ Sbjct: 130 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 189 Query: 212 LSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVEREEWKLDTLCDLYETL 270 SAT+ ++ V +KFM+DP+ I V E +LTL G++Q+Y+ ++ E K L DL + L Sbjct: 190 FSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVL 248 Query: 271 TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330 Q VIF+ + ++ L + + ++F A+H M Q+ER ++F+ R+L+ T+ Sbjct: 249 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 308 Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE-DKRTLRDIET 389 L RG+D+++V++ NYD+P + + Y+HR+ R GRFG KG+AI V++E D + L D++ Sbjct: 309 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 368 Query: 390 FYNTSIEEMPLNV 402 + +I E+P + Sbjct: 369 RFEVNISELPDEI 381 >4D25-A nrPDB Length = 434 Score = 418 bits (1076), Expect = e-117, Method: Composition-based stats. Identities = 116/394 (29%), Positives = 201/394 (51%), Gaps = 16/394 (4%) Query: 20 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG 79 V N ++SF+ NL + +L + G+ KP+ IQ+ AI + G D++ AQ+G Sbjct: 38 VKVSGENPPRPIESFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTG 97 Query: 80 TGKTATFAISILQQIELDLK---------ATQALVLAPTRELAQQIQKVVMALGDYMGAS 130 +GKTA F + I+ + D K Q ++++PTREL QI Sbjct: 98 SGKTAAFLVPIINMLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNEARKFSYGSVLK 157 Query: 131 CHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR 190 GGT VR + + HI+V TPGR+ D + R +S ++ VLD+AD ML Sbjct: 158 VAVAYGGTAVRHQGDNI-ARGCHILVATPGRLHDFVERNRVSFGSVRFVVLDQADCMLDM 216 Query: 191 GFKDQIYDIFQKLN----SNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGI 246 GF I + + Q ++ SAT P D+ + +F+ + + + V + Sbjct: 217 GFMPSIEKMMLHPTMVETTKRQTLMFSATFPEDIQHLAGRFLNNYLFVAVGIVGGASTDV 276 Query: 247 RQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDM 306 Q +I V + E + ++L L E + ++F+ T+R D++ + + S++HGD Sbjct: 277 EQIFIEVTKYEKR-NSLKQLIEENDGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDR 335 Query: 307 DQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRF 366 Q+ER+ ++ F+SG +L+ T + ARG+D++ V +V+NYDLP + + Y+HRIGR GR Sbjct: 336 MQREREEALQNFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRV 395 Query: 367 GRKGVAINMV-TEEDKRTLRDIETFYNTSIEEMP 399 G +G A++ +++D + D+ + + +P Sbjct: 396 GNRGKAVSFYDSDQDLALVADLSKILRQADQSVP 429 >2DB3-A nrPDB Length = 434 Score = 410 bits (1055), Expect = e-115, Method: Composition-based stats. Identities = 112/392 (28%), Positives = 206/392 (52%), Gaps = 11/392 (2%) Query: 16 GMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQ 75 P V S+ + + F +L + ++ + G++ P+ IQ+ +I G D++A Sbjct: 40 NNIPVKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMAC 99 Query: 76 AQSGTGKTATFAISILQQI-----ELDLKATQALVLAPTRELAQQIQKVVMALGDYMGAS 130 AQ+G+GKTA F + IL ++ EL+L Q ++++PTRELA QI Sbjct: 100 AQTGSGKTAAFLLPILSKLLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLK 159 Query: 131 CHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR 190 GGT+ R + + + H+++ TPGR+ D ++R +++ + + VLDEAD ML Sbjct: 160 IGIVYGGTSFRHQNECI-TRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDM 218 Query: 191 GFKDQIYDIFQK--LNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQ 248 GF + + I + Q ++ SAT P ++ + +F+++ + + + ++Q Sbjct: 219 GFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQ 278 Query: 249 FYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQ 308 V + + + L E T ++F+ T+R D+L + ++F +++HGD Q Sbjct: 279 TIYEVNKYAKRSKLIEILSEQADGT--IVFVETKRGADFLASFLSEKEFPTTSIHGDRLQ 336 Query: 309 KERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR 368 +R+ +R+F++GS +VLI T + +RG+D++ + VINYD+P+ ++Y+HRIGR GR G Sbjct: 337 SQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGN 396 Query: 369 KGVAINMVTEE-DKRTLRDIETFYNTSIEEMP 399 G A + E D+ D+ S + +P Sbjct: 397 NGRATSFFDPEKDRAIAADLVKILEGSGQTVP 428 >6B4I-E nrPDB Length = 430 Score = 409 bits (1051), Expect = e-114, Method: Composition-based stats. Identities = 158/403 (39%), Positives = 239/403 (59%), Gaps = 17/403 (4%) Query: 10 RDNGPDGMEPEGVIESNWNEI---VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPC 66 R N D V++ + N V SF+++ L LL+G+YA GF +PS IQ+ A+ Sbjct: 18 RSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLM 77 Query: 67 I--KGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALG 124 + ++IAQ+QSGTGKTA F +++L Q+E K Q L L+PT ELA Q KV+ +G Sbjct: 78 LAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMG 137 Query: 125 DYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDE 183 + A N QK+ I++GTPG V D ++ +++ PK IK+FVLDE Sbjct: 138 KFYPELKLAYAVRGNKLERGQKISE---QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDE 194 Query: 184 ADEML-SRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELT 242 AD M+ ++G +DQ I + L N Q++L SAT V + +K + DP I +K+EE T Sbjct: 195 ADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEET 254 Query: 243 LEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAM 302 L+ I+Q+Y+ + K LC+LY +TI QA+IF +TR+ WL ++ V+ + Sbjct: 255 LDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALL 314 Query: 303 HGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLP------TNRENY 356 G+M ++R ++ FR G +VL+TT++ ARGIDV+QVS+VIN+DLP + E Y Sbjct: 315 SGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETY 374 Query: 357 IHRIGRGGRFGRKGVAINMV-TEEDKRTLRDIETFYNTSIEEM 398 +HRIGR GRFG++G+A+NMV ++ L I+ +N IE + Sbjct: 375 LHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERL 417 >5DTU-A nrPDB Length = 475 Score = 407 bits (1045), Expect = e-114, Method: Composition-based stats. Identities = 116/418 (27%), Positives = 205/418 (49%), Gaps = 36/418 (8%) Query: 20 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG 79 + + ++++ L LL +Y G+++P+ IQ+ AI ++ D+I A +G Sbjct: 30 ISTKGGSIPNPMRNWEESGLPRRLLDIVYRVGYDEPTPIQRAAIPIALQARDLIGVAVTG 89 Query: 80 TGKTATFAISILQQIEL--------DLKATQALVLAPTRELAQQIQKVVMALGDYMGASC 131 +GKTA F + +L I AL+LAPTREL QQI+ D +G + Sbjct: 90 SGKTAAFLLPLLVYISELPPLTEYNKNDGPYALILAPTRELVQQIESEARKFADPLGFTV 149 Query: 132 HACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRG 191 + +GG ++ + L+ IIV TPGR+ D + RR L ++DEAD M+ +G Sbjct: 150 VSIVGGHSLEEQAFALR-NGAEIIVATPGRLVDCIERRLLVFSQCCYVIMDEADRMIDQG 208 Query: 192 FKDQIYDIFQKLN-------------------------SNTQVVLLSATMPSDVLEVTKK 226 F++ + I L Q ++ +ATMP V ++ KK Sbjct: 209 FEEPLTKILDALPVSNEKPDTEDAENPQLMSRYLGGRDRYRQTMMYTATMPPTVEKIAKK 268 Query: 227 FMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQ-AVIFINTRRKV 285 ++R P + + ++ + Q + E+ + L ++ + ++F+N +R Sbjct: 269 YLRRPAIVTIGNAGEAVDTVEQRVEFIAGEDKRKRRLQEILNSGQFKPPIIVFVNIKRNC 328 Query: 286 DWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVI 345 + + + + + F+ +HG Q++R+ + R+G + +L+ TDL RGIDV VSLV+ Sbjct: 329 EMVAKDIKSWGFSTVTLHGSKTQEQREASLAALRNGQAHILVATDLAGRGIDVPDVSLVV 388 Query: 346 NYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFY-NTSIEEMPLNV 402 N+++P+ E Y HRIGR GR G+ GVAI + ED + D++ +SI ++P + Sbjct: 389 NFNMPSTIEAYTHRIGRTGRAGKSGVAITFLGNEDADVMYDLKQIISKSSISKVPEEL 446 >1HV8-A nrPDB Length = 367 Score = 405 bits (1041), Expect = e-113, Method: Composition-based stats. Identities = 135/369 (36%), Positives = 217/369 (58%), Gaps = 10/369 (2%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCI-KGYDVIAQAQSGTGKTATFAISIL 91 +F+++NLS+++L I GFEKP+ IQ + I + Y+++AQA++G+GKTA+FAI ++ Sbjct: 7 NFNELNLSDNILNAIRNKGFEKPTDIQMKVIPLFLNDEYNIVAQARTGSGKTASFAIPLI 66 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEA 151 + + + +A++L PTRELA Q+ + +L GG + +++ L+ Sbjct: 67 ELVN-ENNGIEAIILTPTRELAIQVADEIESLKGNKNLKIAKIYGGKAIYPQIKALK--N 123 Query: 152 PHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL 211 +I+VGTPGR+ D +NR L+ K +K F+LDEADEML+ GF + I N + +++L Sbjct: 124 ANIVVGTPGRILDHINRGTLNLKNVKYFILDEADEMLNMGFIKDVEKILNACNKDKRILL 183 Query: 212 LSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLT 271 SATMP ++L + KK+M D I K I Q Y+ V E + + LC L + Sbjct: 184 FSATMPREILNLAKKYMGDYSFIKAKINA----NIEQSYVEVNENE-RFEALCRLLKNKE 238 Query: 272 ITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDL 331 ++F T+R L + F A+HGD+ Q +R+ ++R F+ R+LI TD+ Sbjct: 239 FY-GLVFCKTKRDTKELASMLRDIGFKAGAIHGDLSQSQREKVIRLFKQKKIRILIATDV 297 Query: 332 LARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFY 391 ++RGIDV ++ VINY LP N E+Y+HRIGR GR G+KG AI+++ + + LR IE Sbjct: 298 MSRGIDVNDLNCVINYHLPQNPESYMHRIGRTGRAGKKGKAISIINRREYKKLRYIERAM 357 Query: 392 NTSIEEMPL 400 I+++ Sbjct: 358 KLKIKKLKF 366 >5SUQ-A nrPDB Length = 446 Score = 403 bits (1035), Expect = e-113, Method: Composition-based stats. Identities = 134/372 (36%), Positives = 215/372 (57%), Gaps = 7/372 (1%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F D L L R I GFE PS +QQ I I G DV+ QA+SG GKTA F +S LQQ Sbjct: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQME-- 150 ++ +V+ RELA QI+ + YM GGT + + + L+ + Sbjct: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQV 209 APHI+V TPGR+ ++ +Y+ ++K FV+DE D++L + + +IF+ + QV Sbjct: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 Query: 210 VLLSATMPSDVLEVTKKFMRDPIRILVKKEE-LTLEGIRQFYINVEREEWKLDTLCDLYE 268 ++ SAT+ ++ + ++F+++P+ I V E LTL G++Q+YI +E E K L L + Sbjct: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLE-EREKNRKLAQLLD 302 Query: 269 TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328 L Q +IF+ + + + LT+ ++A +F +HG M Q+ER + F+ R+ ++ Sbjct: 303 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 362 Query: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV-TEEDKRTLRDI 387 TD+ RGID+++++L INYDL + Y+HR+GR GRFG KG+AI+ V ++ED+ L I Sbjct: 363 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 422 Query: 388 ETFYNTSIEEMP 399 + ++ I E P Sbjct: 423 QERFDVKIAEFP 434 >5SUP-A nrPDB Length = 390 Score = 400 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 134/372 (36%), Positives = 215/372 (57%), Gaps = 7/372 (1%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F D L L R I GFE PS +QQ I I G DV+ QA+SG GKTA F +S LQQ Sbjct: 8 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 67 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQME-- 150 ++ +V+ RELA QI+ + YM GGT + + + L+ + Sbjct: 68 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 127 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQV 209 APHI+V TPGR+ ++ +Y+ ++K FV+DE D++L + + +IF+ + QV Sbjct: 128 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 187 Query: 210 VLLSATMPSDVLEVTKKFMRDPIRILVKKEE-LTLEGIRQFYINVEREEWKLDTLCDLYE 268 ++ SAT+ ++ + ++F+++P+ I V E LTL G++Q+YI +E E K L L + Sbjct: 188 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLE-EREKNRKLAQLLD 246 Query: 269 TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328 L Q +IF+ + + + LT+ ++A +F +HG M Q+ER + F+ R+ ++ Sbjct: 247 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 306 Query: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV-TEEDKRTLRDI 387 TD+ RGID+++++L INYDL + Y+HR+GR GRFG KG+AI+ V ++ED+ L I Sbjct: 307 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 366 Query: 388 ETFYNTSIEEMP 399 + ++ I E P Sbjct: 367 QERFDVKIAEFP 378 >3PEW-A nrPDB Length = 395 Score = 396 bits (1017), Expect = e-110, Method: Composition-based stats. Identities = 149/381 (39%), Positives = 237/381 (62%), Gaps = 16/381 (4%) Query: 32 DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIK--GYDVIAQAQSGTGKTATFAIS 89 SFD++ L+ LL+GIYA F+KPS IQ+RA+ + ++IAQ+QSGTGKTA F+++ Sbjct: 5 KSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSLT 64 Query: 90 ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQM 149 +L ++ + + QA+ LAP+RELA+Q +VV +G + + + +K + Sbjct: 65 MLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIV-----PDSFEKNKQ 119 Query: 150 EAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQ 208 +IVGTPG V D++ R+ + + IK+FVLDEAD ML + G DQ + + L +TQ Sbjct: 120 INAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQ 179 Query: 209 VVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYE 268 +VL SAT V + KK + + + ++ E+ ++ I+Q Y++ + E K D L +LY Sbjct: 180 LVLFSATFADAVRQYAKKIVPNANTLELQTNEVNVDAIKQLYMDCKNEADKFDVLTELYG 239 Query: 269 TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328 +TI ++IF+ T++ + L K+ + VS +HGD+ +ERD ++ +FR G S+VLIT Sbjct: 240 VMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLIT 299 Query: 329 TDLLARGIDVQQVSLVINYDLPT------NRENYIHRIGRGGRFGRKGVAINMVTEEDK- 381 T++LARGID+ VS+V+NYDLPT + YIHRIGR GRFGRKGVAI+ V +++ Sbjct: 300 TNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAISFVHDKNSF 359 Query: 382 RTLRDIETFY-NTSIEEMPLN 401 L I+ ++ + + +P + Sbjct: 360 NILSAIQKYFGDIEMTRVPTD 380 >6CB1-p nrPDB Length = 505 Score = 379 bits (973), Expect = e-105, Method: Composition-based stats. Identities = 121/421 (28%), Positives = 213/421 (50%), Gaps = 28/421 (6%) Query: 1 MSASQDSRSRDNG--PDGMEPEGVI--------ESNWNEIVDSFDDMNLSESLLRGIYAY 50 M+ + RSRD+ + + E E V+ F+++ LS+ L+ I Sbjct: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM 60 Query: 51 GFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIEL----DLKATQALVL 106 GF +++Q R I P + G DV+ A++G+GKT F I ++ + T +V+ Sbjct: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 Query: 107 APTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDML 166 PTRELA QI V L ++ + IGG N R E +KL M+ ++++ TPGR+ D L Sbjct: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKL-MKGVNMLIATPGRLLDHL 179 Query: 167 NR-RYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLN-SNTQVVLLSATMPSDVLEVT 224 + K +K ++DEAD +L GF+D++ I + L + Q +L SAT + V ++ Sbjct: 180 QNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLA 239 Query: 225 KKFMRD-PIRILV--KKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINT 281 + +R P+ I V + + T +G+ Q Y+ + ++ + L + + ++F+++ Sbjct: 240 RISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDK-RFLLLFSFLKRNQKKKIIVFLSS 298 Query: 282 RRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQV 341 V + E ++ D V +HG Q++R EF + +LI TD+ ARG+D+ V Sbjct: 299 CNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAV 358 Query: 342 SLVINYDLPTNRENYIHRIGRGGRFGR-KGVAINMVTEEDKRTLRDIETFYNTSIEEMPL 400 +I +D P + +YIHR+GR R + KG ++ +T + LR ++ ++PL Sbjct: 359 DWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKA------SKVPL 412 Query: 401 N 401 N Sbjct: 413 N 413 >4KBG-A nrPDB Length = 365 Score = 361 bits (928), Expect = e-100, Method: Composition-based stats. Identities = 119/369 (32%), Positives = 195/369 (52%), Gaps = 9/369 (2%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92 F D L +L ++ G P+ IQ A+ ++G D+I QA++GTGKT FA+ I + Sbjct: 2 EFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAE 61 Query: 93 QIELDL---KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQM 149 ++ + +ALVL PTRELA Q+ + A+ ++ A GGT + + L + Sbjct: 62 RLAPSQERGRKPRALVLTPTRELALQVASELTAVAPHL--KVVAVYGGTGYGKQKEAL-L 118 Query: 150 EAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQV 209 +V TPGR D L + L +++ VLDEADEMLS GF++++ + + Q Sbjct: 119 RGADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQT 178 Query: 210 VLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYET 269 +L SAT+PS + +++M++P+ I V K+E V +L+ L DL Sbjct: 179 LLFSATLPSWAKRLAERYMKNPVLINVIKDEPVTYEEEAVPAPV---RGRLEVLSDLLYV 235 Query: 270 LTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITT 329 + +A++F T+ + + + + + A+HGD+ Q ER+ ++ FR G RVL+ T Sbjct: 236 ASPDRAMVFTRTKAETEEIAQGLLRLGHPAQALHGDLSQGERERVLGAFRQGEVRVLVAT 295 Query: 330 DLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIET 389 D+ ARG+D+ QV LV++Y LP E Y HR GR GR GR G + + ++R + +E Sbjct: 296 DVAARGLDIPQVDLVVHYRLPDRAEAYQHRSGRTGRAGRGGRVVLLYGPRERRDVEALER 355 Query: 390 FYNTSIEEM 398 + + Sbjct: 356 AVGRRFKRV 364 >3FHO-A nrPDB Length = 508 Score = 361 bits (927), Expect = e-100, Method: Composition-based stats. Identities = 142/355 (40%), Positives = 215/355 (60%), Gaps = 15/355 (4%) Query: 57 AIQQRAILPCIK--GYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQ 114 IQ++A+ + ++I Q+QSGTGKTA FA+++L +++ + QA+ LAP+RELA+ Sbjct: 144 KIQEKALPLLLSNPPRNMIGQSQSGTGKTAAFALTMLSRVDASVPKPQAICLAPSRELAR 203 Query: 115 QIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPK 174 QI VV +G Y I + V K I++GTPG V D++ RR L + Sbjct: 204 QIMDVVTEMGKYTEVKTAFGI-----KDSVPKGAKIDAQIVIGTPGTVMDLMKRRQLDAR 258 Query: 175 YIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIR 233 IK+FVLDEAD ML + G DQ I L NTQ+VL SAT V + ++F + Sbjct: 259 DIKVFVLDEADNMLDQQGLGDQSMRIKHLLPRNTQIVLFSATFSERVEKYAERFAPNANE 318 Query: 234 ILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH 293 I +K EEL++EGI+Q Y++ + EE K + L +LY LTI Q++IF + + + +M Sbjct: 319 IRLKTEELSVEGIKQLYMDCQSEEHKYNVLVELYGLLTIGQSIIFCKKKDTAEEIARRMT 378 Query: 294 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLP--- 350 A TV+ + G+++ +RD IM FR G+S+VL+TT+++ARGIDV QV+LV+NYD+P Sbjct: 379 ADGHTVACLTGNLEGAQRDAIMDSFRVGTSKVLVTTNVIARGIDVSQVNLVVNYDMPLDQ 438 Query: 351 ---TNRENYIHRIGRGGRFGRKGVAINMVTEEDK-RTLRDIETFYNTSIEEMPLN 401 + + Y+HRIGR GRFGR GV+IN V ++ + I+ ++ I +P + Sbjct: 439 AGRPDPQTYLHRIGRTGRFGRVGVSINFVHDKKSWEEMNAIQEYFQRPITRVPTD 493 >4LJY-A nrPDB Length = 493 Score = 354 bits (909), Expect = 4e-98, Method: Composition-based stats. Identities = 104/408 (25%), Positives = 191/408 (46%), Gaps = 32/408 (7%) Query: 16 GMEPEGVIESNWNEIVDSFDDMNLSESLLRGI-YAYGFEKPSAIQQRAILPCIKGYDVIA 74 ++ + + + V + + LS + I F + IQ +A+ + G DVI Sbjct: 34 SLDNIKIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSLTPIQSQALPAIMSGRDVIG 93 Query: 75 QAQSGTGKTATFAISILQQIELDLK------ATQALVLAPTRELAQQIQKVVMALGDY-M 127 +++G+GKT ++ + +L+Q++ L+LAPTRELA QI + V + Sbjct: 94 ISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGLILAPTRELALQIHEEVTKFTEADT 153 Query: 128 GASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDML---NRRYLSPKYIKMFVLDEA 184 C GG+ ++ ++ L+ I+V TPGR D+L + + LS K I V+DEA Sbjct: 154 SIRSVCCTGGSEMKKQITDLK-RGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEA 212 Query: 185 DEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLE 244 D + GF+ QI I + + + Q VL SAT P+ + + + PI I + + + E Sbjct: 213 DRLFDLGFEPQITQIMKTVRPDKQCVLFSATFPNKLRSFAVRVLHSPISITINSKGMVNE 272 Query: 245 GIRQFYINVEREEWKLDTLCDLYETLT--------------------ITQAVIFINTRRK 284 ++Q + E+ K D L L + +A+IF++++ Sbjct: 273 NVKQKFRICHSEDEKFDNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNI 332 Query: 285 VDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLV 344 D++++K+ A+H +ER + + +F+ + +L+ T++L+RG++V +VSLV Sbjct: 333 CDFISKKLLNAGIVTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLV 392 Query: 345 INYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYN 392 I Y+ Y+H GR R R G AI ++ ++ + Sbjct: 393 IIYNAVKTFAQYVHTTGRTARGSRSGTAITLLLHDELSGAYILSKAMR 440 >5ZWN-y nrPDB Length = 588 Score = 352 bits (903), Expect = 2e-97, Method: Composition-based stats. Identities = 119/405 (29%), Positives = 199/405 (49%), Gaps = 31/405 (7%) Query: 24 ESNWNEIVDSFDDMNL-SESLLRGIY-AYGFEKPSAIQQRAILPCI---KGYDVIAQAQS 78 + +++++N+ LLR I F P+ IQ+ I + D + A + Sbjct: 164 GGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVAST 223 Query: 79 GTGKTATFAISILQQIELDL---------KATQALVLAPTRELAQQIQKVVMALGD---- 125 G+GKT F I IL ++ +AL+LAPTREL QQIQK + Sbjct: 224 GSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSK 283 Query: 126 --YMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDE 183 + +GG ++ E+ E I+V TPGR+ D L L K ++ VLDE Sbjct: 284 ESNYDCKVISIVGGHSL-EEISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLDE 342 Query: 184 ADEMLSRGFKDQIYDIFQKLN------SNTQVVLLSATMPSDVLEVTKKFMRDPIRILVK 237 AD+M+ GF+DQ+ +I K++ N Q ++ +ATM + ++ +M+ P+ + Sbjct: 343 ADKMIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVYATIG 402 Query: 238 KEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHAR-D 296 E + I+Q + +E K L + +IFIN ++ DWL EK + Sbjct: 403 VETGSEPLIQQVVEYADNDEDKFKKLKPIVAKY-DPPIIIFINYKQTADWLAEKFQKETN 461 Query: 297 FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENY 356 V+ +HG Q++R+ ++ FR+ +++I T++ ARG+D+ VSLV+N+ + ++Y Sbjct: 462 MKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDY 521 Query: 357 IHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLN 401 IHRIGR GR +G A++ V+ + +L I Y + PLN Sbjct: 522 IHRIGRTGRAANEGTAVSFVSAAEDESL--IRELYKYVRKHDPLN 564 >4W7S-A nrPDB Length = 463 Score = 351 bits (900), Expect = 4e-97, Method: Composition-based stats. Identities = 119/405 (29%), Positives = 199/405 (49%), Gaps = 31/405 (7%) Query: 24 ESNWNEIVDSFDDMNL-SESLLRGIY-AYGFEKPSAIQQRAILPCI---KGYDVIAQAQS 78 + +++++N+ LLR I F P+ IQ+ I + D + A + Sbjct: 39 GGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVAST 98 Query: 79 GTGKTATFAISILQQIELDL---------KATQALVLAPTRELAQQIQKVVMALGD---- 125 G+GKT F I IL ++ +AL+LAPTREL QQIQK + Sbjct: 99 GSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSK 158 Query: 126 --YMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDE 183 + +GG ++ E+ E I+V TPGR+ D L L K ++ VLDE Sbjct: 159 ESNYDCKVISIVGGHSL-EEISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLDE 217 Query: 184 ADEMLSRGFKDQIYDIFQKLN------SNTQVVLLSATMPSDVLEVTKKFMRDPIRILVK 237 AD+M+ GF+DQ+ +I K++ N Q ++ +ATM + ++ +M+ P+ + Sbjct: 218 ADKMIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVYATIG 277 Query: 238 KEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHAR-D 296 E + I+Q + +E K L + +IFIN ++ DWL EK + Sbjct: 278 VETGSEPLIQQVVEYADNDEDKFKKLKPIVAKY-DPPIIIFINYKQTADWLAEKFQKETN 336 Query: 297 FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENY 356 V+ +HG Q++R+ ++ FR+ +++I T++ ARG+D+ VSLV+N+ + ++Y Sbjct: 337 MKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDY 396 Query: 357 IHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLN 401 IHRIGR GR +G A++ V+ + +L I Y + PLN Sbjct: 397 IHRIGRTGRAANEGTAVSFVSAAEDESL--IRELYKYVRKHDPLN 439 >2Z0M-A nrPDB Length = 337 Score = 339 bits (869), Expect = 2e-93, Method: Composition-based stats. Identities = 103/341 (30%), Positives = 179/341 (52%), Gaps = 18/341 (5%) Query: 39 LSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDL 98 ++E + + I GF+ + +Q + I ++G +V+ +A++G+GKTA +AI IL+ Sbjct: 1 MNEKIEQAIREMGFKNFTEVQSKTIPLMLQGKNVVVRAKTGSGKTAAYAIPILEL----- 55 Query: 99 KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGT 158 ++LV+ PTREL +Q+ + +G YM GG +A++ +++ I+V T Sbjct: 56 -GMKSLVVTPTRELTRQVASHIRDIGRYMDTKVAEVYGGMPYKAQINRVR--NADIVVAT 112 Query: 159 PGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPS 218 PGR+ D+ ++ + ++ ++DEAD M GF D I I + ++ L SAT+P Sbjct: 113 PGRLLDLWSKGVIDLSSFEIVIIDEADLMFEMGFIDDIKIILAQTSNRKITGLFSATIPE 172 Query: 219 DVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIF 278 ++ +V K F+ + I + + L + +++V+ ++W+ ++F Sbjct: 173 EIRKVVKDFITNYEEI---EACIGLANVEHKFVHVK-DDWRSK--VQALRENKDKGVIVF 226 Query: 279 INTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDV 338 + TR +V L + GD+ Q R+ + FR G +LITTD+ +RG+D+ Sbjct: 227 VRTRNRVAKLVRLFDN----AIELRGDLPQSVRNRNIDAFREGEYDMLITTDVASRGLDI 282 Query: 339 QQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE 379 V VIN+D P + YIHRIGR GR GRKG AI + E Sbjct: 283 PLVEKVINFDAPQDLRTYIHRIGRTGRMGRKGEAITFILNE 323 >3SQW-A nrPDB Length = 579 Score = 324 bits (830), Expect = 5e-89, Method: Composition-based stats. Identities = 116/395 (29%), Positives = 200/395 (50%), Gaps = 34/395 (8%) Query: 35 DDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKG--YDVIAQAQSGTGKTATFAISILQ 92 ++ L + + + I F + +QQ+ I P + +DVIA+A++GTGKT F I I Q Sbjct: 24 EEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQ 83 Query: 93 QI---ELDLKA-TQALVLAPTRELAQQIQKVVMALGD-YMGASCHACI---GGTNVRAEV 144 + + D + +A+++APTR+LA QI+ V + D G +AC+ GGT+ RA + Sbjct: 84 HLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAM 143 Query: 145 QKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMF---VLDEADEMLSRGFKDQIYDIFQ 201 K+ P+I++ TPGR+ D+L + S K+ + VLDEAD +L GF+D + I Sbjct: 144 NKMNKLRPNIVIATPGRLIDVLEK--YSNKFFRFVDYKVLDEADRLLEIGFRDDLETISG 201 Query: 202 KLNS-------NTQVVLLSATMPSDVLEVTKKFMRDPIRILV----KKEELTLEGIRQFY 250 LN N + +L SAT+ V ++ M + + K E E I Q Sbjct: 202 ILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSV 261 Query: 251 INVEREEWKLDTLCD-----LYETLTITQAVIFINTRRKVDWLTEKMH---ARDFTVSAM 302 + E+ + + + E + +A+IF T + +L + +D + Sbjct: 262 VISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEF 321 Query: 303 HGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 362 HG + Q +R +++ F+ S +L+ TD+ ARG+D V V+ +P+ NYIHRIGR Sbjct: 322 HGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGR 381 Query: 363 GGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEE 397 R G++G ++ + +++ +R++E N I + Sbjct: 382 TARSGKEGSSVLFICKDELPFVRELEDAKNIVIAK 416 >3I62-A nrPDB Length = 563 Score = 321 bits (823), Expect = 4e-88, Method: Composition-based stats. Identities = 117/436 (26%), Positives = 212/436 (48%), Gaps = 44/436 (10%) Query: 6 DSRSRDNGPDGMEPEGVIESNWNEIVDS--------------FDDMNLSESLLRGIYAYG 51 +SR R + + ++ +++++ ++ L + + + I Sbjct: 32 NSRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRME 91 Query: 52 FEKPSAIQQRAILPCIKG--YDVIAQAQSGTGKTATFAISILQQI---ELDLKA-TQALV 105 F + +QQ+ I P + +DVIA+A++GTGKT F I I Q + + D + +A++ Sbjct: 92 FPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVI 151 Query: 106 LAPTRELAQQIQKVVMALGD-YMGASCHACI---GGTNVRAEVQKLQMEAPHIIVGTPGR 161 +APTR+LA QI+ V + D G +AC+ GGT+ RA + K+ P+I++ TPGR Sbjct: 152 VAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATPGR 211 Query: 162 VFDMLNRRYLSP-KYIKMFVLDEADEMLSRGFKDQIYDIFQKLNS-------NTQVVLLS 213 + D+L + +++ VLDEAD +L GF+D + I LN N + +L S Sbjct: 212 LIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFS 271 Query: 214 ATMPSDVLEVTKKFMRDPIRILV----KKEELTLEGIRQFYINVEREEWKLDTLCD---- 265 AT+ V ++ M + + K E E I Q + E+ + + Sbjct: 272 ATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISEKFANSIFAAVEHIKK 331 Query: 266 -LYETLTITQAVIFINTRRKVDWLTEKMH---ARDFTVSAMHGDMDQKERDVIMREFRSG 321 + E + +A+IF T + +L + +D + HG + Q +R +++ F+ Sbjct: 332 QIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKD 391 Query: 322 SSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDK 381 S +L+ TD+ ARG+D V V+ +P+ NYIHRIGR R G++G ++ + +++ Sbjct: 392 ESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDEL 451 Query: 382 RTLRDIETFYNTSIEE 397 +R++E N I + Sbjct: 452 PFVRELEDAKNIVIAK 467 >5ZBZ-A nrPDB Length = 220 Score = 311 bits (797), Expect = 3e-85, Method: Composition-based stats. Identities = 219/219 (100%), Positives = 219/219 (100%) Query: 20 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG 79 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG Sbjct: 2 EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSG 61 Query: 80 TGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 139 TGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN Sbjct: 62 TGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 121 Query: 140 VRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDI 199 VRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDI Sbjct: 122 VRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDI 181 Query: 200 FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK 238 FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK Sbjct: 182 FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK 220 >3BOR-A nrPDB Length = 237 Score = 310 bits (794), Expect = 7e-85, Method: Composition-based stats. Identities = 198/219 (90%), Positives = 213/219 (97%) Query: 21 GVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGT 80 GVIESNWNEIVD+FDDMNL ESLLRGIYAYGFEKPSAIQQRAI+PCIKGYDVIAQAQSGT Sbjct: 19 GVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGT 78 Query: 81 GKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNV 140 GKTATFAISILQQ+E++ K TQALVLAPTRELAQQIQKV++ALGDYMGA+CHACIGGTNV Sbjct: 79 GKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNV 138 Query: 141 RAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIF 200 R E+QKLQ EAPHI+VGTPGRVFDMLNRRYLSPK+IKMFVLDEADEMLSRGFKDQIY+IF Sbjct: 139 RNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIF 198 Query: 201 QKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKE 239 QKLN++ QVVLLSATMP+DVLEVTKKFMRDPIRILVKKE Sbjct: 199 QKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE 237 >4CDG-A nrPDB Length = 673 Score = 279 bits (714), Expect = 2e-75, Method: Composition-based stats. Identities = 71/372 (19%), Positives = 139/372 (37%), Gaps = 25/372 (6%) Query: 32 DSFDDMNLS--ESLLRGIYA-YGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAI 88 + F ++ + +++ + +G Q AI + G D +G GK+ + + Sbjct: 9 ERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQL 68 Query: 89 SILQQIELDLKATQALVLAPTREL-AQQIQKVV-------MALGDYMGASCHACIGGTNV 140 + +V++P R L Q+QK+ GD + + Sbjct: 69 PAC------VSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSK 122 Query: 141 RAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRG--FKDQIYD 198 + + KL P I + R+ L Y K + FV+DEA + G F+ Sbjct: 123 KDPIIKLLYVTPEKICAS-NRLISTLENLY-ERKLLARFVIDEAHCVSQWGHDFRQDYKR 180 Query: 199 I--FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVERE 256 + ++ + V+ L+AT V + ++ +R V ++ + + + + Sbjct: 181 MNMLRQKFPSVPVMALTATANPRVQKDILTQLK-ILRPQVFSMSFNRHNLKYYVLPKKPK 239 Query: 257 EWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMR 316 + D L + + +I+ +RR+ D + + + A H + RD + + Sbjct: 240 KVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQ 299 Query: 317 EF-RSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINM 375 ++ +V+ T GID V VI+ LP + E Y GR GR G + Sbjct: 300 KWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLF 359 Query: 376 VTEEDKRTLRDI 387 T D L+ + Sbjct: 360 YTYHDVTRLKRL 371 >1QVA-A nrPDB Length = 223 Score = 273 bits (699), Expect = 7e-74, Method: Composition-based stats. Identities = 139/220 (63%), Positives = 169/220 (76%), Gaps = 2/220 (0%) Query: 17 MEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQA 76 E I++N+ ++V FDDM L E LLRG++ YGFE+PSAIQQRAI+P I+G+DV+AQA Sbjct: 6 DIEESQIQTNYQKVVYKFDDMELDEQLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQA 65 Query: 77 QSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIG 136 QSGTGKT TF+I+ LQ+I+ +KA QAL+LAPTRELA QIQKVVMAL +M HACIG Sbjct: 66 QSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIG 125 Query: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 196 GT+ + + L+ I+VGTPGRVFD + RR IKMF+LDEADEMLS GFK+QI Sbjct: 126 GTSFVEDAEGLR--DAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQI 183 Query: 197 YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILV 236 Y IF L TQVVLLSATMP+DVLEVT KFMR+P+RILV Sbjct: 184 YQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILV 223 >1WRB-A nrPDB Length = 253 Score = 266 bits (681), Expect = 9e-72, Method: Composition-based stats. Identities = 73/248 (29%), Positives = 129/248 (52%), Gaps = 16/248 (6%) Query: 16 GMEPEGVIESNWN--EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVI 73 P V +++ ++++FD++ L ++ I +++P+ IQ+ AI ++ D++ Sbjct: 5 DSIPVSVTGPDYSATNVIENFDELKLDPTIRNNILLASYQRPTPIQKNAIPAILEHRDIM 64 Query: 74 AQAQSGTGKTATFAISILQQI---------ELDLKATQALVLAPTRELAQQIQKVVMALG 124 A AQ+G+GKTA F I I+ + + L+LAPTRELA QI Sbjct: 65 ACAQTGSGKTAAFLIPIINHLVCQDLNQQRYSKTAYPKCLILAPTRELAIQILSESQKFS 124 Query: 125 DYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEA 184 GG + ++++++QM H++V TPGR+ D + + +S ++ K VLDEA Sbjct: 125 LNTPLRSCVVYGGADTHSQIREVQM-GCHLLVATPGRLVDFIEKNKISLEFCKYIVLDEA 183 Query: 185 DEMLSRGFKDQIYDIFQKLNS----NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240 D ML GF+ QI I ++ N N Q ++ SAT P ++ ++ F+ + I + V + Sbjct: 184 DRMLDMGFEPQIRKIIEESNMPSGINRQTLMFSATFPKEIQKLAADFLYNYIFMTVGRVG 243 Query: 241 LTLEGIRQ 248 T + I+Q Sbjct: 244 STSDSIKQ 251 >4PX9-A nrPDB Length = 292 Score = 264 bits (675), Expect = 5e-71, Method: Composition-based stats. Identities = 71/245 (28%), Positives = 118/245 (48%), Gaps = 23/245 (9%) Query: 16 GMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQ 75 P +N ++SF D+ + E ++ I + +P+ +Q+ AI + D++A Sbjct: 49 DDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMAC 108 Query: 76 AQSGTGKTATFAISILQQIELD------------------LKATQALVLAPTRELAQQIQ 117 AQ+G+GKTA F + IL QI D + +LVLAPTRELA QI Sbjct: 109 AQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIY 168 Query: 118 KVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIK 177 + GG ++ +++ L+ H++V TPGR+ DM+ R + + K Sbjct: 169 EEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGCHLLVATPGRLVDMMERGKIGLDFCK 227 Query: 178 MFVLDEADEMLSRGFKDQIYDIFQK--LNSN--TQVVLLSATMPSDVLEVTKKFMRDPIR 233 VLDEAD ML GF+ QI I ++ + ++ SAT P ++ + + F+ + I Sbjct: 228 YLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIF 287 Query: 234 ILVKK 238 + V + Sbjct: 288 LAVGR 292 >6CRM-A nrPDB Length = 541 Score = 263 bits (673), Expect = 8e-71, Method: Composition-based stats. Identities = 79/365 (21%), Positives = 149/365 (40%), Gaps = 33/365 (9%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 + L++ +L+ + Y +P Q I ++G D + +G GK+ + I L Sbjct: 27 YSQETLAKQVLQETFGYQQFRPG--QATIIDAVLEGRDCLVVMPTGGGKSLCYQIPAL-- 82 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEA-- 151 +K +V++P L + ++A G AC+ T R E Q + Sbjct: 83 ----VKTGLTIVVSPLISLMKDQVDQLLANG-----VAAACLNSTQSREEQQAVLAGCRT 133 Query: 152 --PHIIVGTPGRVFDMLNR--RYLSPKYIKMFVLDEADEMLSRG--FKDQIYDIFQKLNS 205 ++ P R+ M++ L + M +DEA + G F+ + + Q Sbjct: 134 GQVRLLYIAPERL--MMDNFIDTLGYWDLAMVAVDEAHCISQWGHDFRPEYAALGQLRAR 191 Query: 206 NTQV--VLLSATMPSDVLEVTKKFM--RDPIRILVKKEELTLEGIRQFYINVEREEWKLD 261 V + L+AT + + DP L++ IR Y+ +E+ + LD Sbjct: 192 FPAVPFMALTATADDTTRRDIVRLLGLDDP---LIEISSFDRPNIR--YMLMEKFKP-LD 245 Query: 262 TLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSG 321 L + +I+ N+R KV+ ++ +R + +A H ++ + R + +F+ Sbjct: 246 QLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSRGISAAAYHAGLEHEVRASVQEKFQRD 305 Query: 322 SSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDK 381 ++++ T GI+ V V+++D+P N E+Y GR GR G A+ D Sbjct: 306 DLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADM 365 Query: 382 RTLRD 386 LR Sbjct: 366 AWLRR 370 >3FE2-A nrPDB Length = 242 Score = 256 bits (653), Expect = 2e-68, Method: Composition-based stats. Identities = 69/229 (30%), Positives = 111/229 (48%), Gaps = 6/229 (2%) Query: 18 EPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQ 77 + V N + V +F + N +++ I F +P+AIQ + + G D++ AQ Sbjct: 15 KEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQ 74 Query: 78 SGTGKTATFAISILQQIELDL-----KATQALVLAPTRELAQQIQKVVMALGDYMGASCH 132 +G+GKT ++ + + I LVLAPTRELAQQ+Q+V Sbjct: 75 TGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKST 134 Query: 133 ACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGF 192 GG +++ L+ I + TPGR+ D L + + VLDEAD ML GF Sbjct: 135 CIYGGAPKGPQIRDLE-RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGF 193 Query: 193 KDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241 + QI I ++ + Q ++ SAT P +V ++ + F++D I I + EL Sbjct: 194 EPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALEL 242 >5GJU-A nrPDB Length = 205 Score = 255 bits (651), Expect = 3e-68, Method: Composition-based stats. Identities = 81/205 (39%), Positives = 121/205 (59%), Gaps = 2/205 (0%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92 +F D+ L +L + G+EKPS IQ I + G DV+ AQ+G+GKTA F++ +LQ Sbjct: 2 TFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQ 61 Query: 93 QIELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEA 151 ++ +LKA Q LVLAPTRELA Q+ + + +M G + A GG +++ L+ + Sbjct: 62 NLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQLRALR-QG 120 Query: 152 PHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL 211 P I+VGTPGR+ D L R L + VLDEADEML GF + + I ++ Q L Sbjct: 121 PQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIPEGHQTAL 180 Query: 212 LSATMPSDVLEVTKKFMRDPIRILV 236 SATMP + +T++FM++P + + Sbjct: 181 FSATMPEAIRRITRRFMKEPQEVRI 205 >1T6N-A nrPDB Length = 220 Score = 254 bits (648), Expect = 7e-68, Method: Composition-based stats. Identities = 81/205 (39%), Positives = 115/205 (56%), Gaps = 2/205 (0%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F D L LLR I GFE PS +Q I I G DV+ QA+SG GKTA F ++ LQQ Sbjct: 16 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 75 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAP 152 +E LV+ TRELA QI K YM GG +++ + + L+ P Sbjct: 76 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 135 Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQVVL 211 HI+VGTPGR+ + + L+ K+IK F+LDE D+ML + + + +IF+ QV++ Sbjct: 136 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 195 Query: 212 LSATMPSDVLEVTKKFMRDPIRILV 236 SAT+ ++ V +KFM+DP+ I V Sbjct: 196 FSATLSKEIRPVCRKFMQDPMEIFV 220 >5LST-A nrPDB Length = 693 Score = 251 bits (641), Expect = 5e-67, Method: Composition-based stats. Identities = 89/421 (21%), Positives = 158/421 (37%), Gaps = 61/421 (14%) Query: 13 GPDGMEPEGVIESNWN-EIVDSFDDMNLS--------------ESLLRGIYAYGFEKPSA 57 GP + PE ++ S V S D L + + + G + Sbjct: 1 GPMAVGPEPLVPSPQPVPEVPSLDPTVLPLYSLGPSGQLAETPAEVFQALEQLGHQAFRP 60 Query: 58 IQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQ 117 Q+RA++ + G + +G GK+ + + L + LV++P L + Sbjct: 61 GQERAVMRILSGISTLLVLPTGAGKSLCYQLPAL--LYSRRSPCLTLVVSPLLSL---MD 115 Query: 118 KVVMALGDYMGASC-HACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFD---MLNRRYLSP 173 V L + A+C H+ + + +QK++ H+++ TP + + L P Sbjct: 116 DQVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPP 175 Query: 174 KYIKMFVLDEADEM--LSRGFKDQIYDIFQKLNSNTQV---VLLSATMPSDVLEVTKKFM 228 + +DEA + S F+ + + L V + L+AT T++ Sbjct: 176 --VAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTAT-------ATRRTA 226 Query: 229 RDPIRILVKKEELTLEGIR------QFYINVERE-EWKLDTLCDLYETLTITQAVIFINT 281 D + L EE L G ++++R+ + L TL + +I+ N Sbjct: 227 SDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNR 286 Query: 282 RRKVDWLTEKMH--------------ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLI 327 R + + + A T A H M +ER + R F G RV++ Sbjct: 287 REDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVV 346 Query: 328 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTE--EDKRTLR 385 T G+D V V++ LP + E+Y+ +GR GR G+ + ED R LR Sbjct: 347 ATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELR 406 Query: 386 D 386 Sbjct: 407 R 407 >1OYY-A nrPDB Length = 523 Score = 248 bits (634), Expect = 3e-66, Method: Composition-based stats. Identities = 71/357 (19%), Positives = 142/357 (39%), Gaps = 29/357 (8%) Query: 40 SESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLK 99 ++ +L+ + Y +P Q+ I + G D + +G GK+ + I L L Sbjct: 13 AKQVLQETFGYQQFRPG--QEEIIDTVLSGRDCLVVMPTGGGKSLCYQIPAL------LL 64 Query: 100 ATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKL----QMEAPHII 155 +V++P L + + A G AC+ T R + ++ + ++ Sbjct: 65 NGLTVVVSPLISLMKDQVDQLQANG-----VAAACLNSTQTREQQLEVMTGCRTGQIRLL 119 Query: 156 VGTPGRVFDMLNRRYLSPKYIK--MFVLDEADEMLSRG--FKDQIYDIFQKLNSNT--QV 209 P R+ ML+ + + +DEA + G F+ + + Q Sbjct: 120 YIAPERL--MLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRPEYAALGQLRQRFPTLPF 177 Query: 210 VLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYET 269 + L+AT + + + L++ IR Y+ +E+ + LD L + Sbjct: 178 MALTATADDTTRQDIVRLLG-LNDPLIQISSFDRPNIR--YMLMEKFKP-LDQLMRYVQE 233 Query: 270 LTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITT 329 +I+ N+R KV+ ++ ++ + +A H ++ R + +F+ ++++ T Sbjct: 234 QRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVAT 293 Query: 330 DLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRD 386 GI+ V V+++D+P N E+Y GR GR G A+ D LR Sbjct: 294 VAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADMAWLRR 350 >1VEC-A nrPDB Length = 206 Score = 246 bits (628), Expect = 1e-65, Method: Composition-based stats. Identities = 75/205 (36%), Positives = 125/205 (60%), Gaps = 2/205 (0%) Query: 32 DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL 91 + F+D L LL GI+ G+EKPS IQ+ +I + G D++A+A++GTGK+ + I +L Sbjct: 3 NEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL 62 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQME 150 ++++L QA+V+ PTRELA Q+ ++ + + +M GA A GGTN+R ++ +L + Sbjct: 63 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLD-D 121 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV 210 H+++ TPGR+ D++ + +++M VLDEAD++LS+ F + DI L N Q++ Sbjct: 122 TVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQIL 181 Query: 211 LLSATMPSDVLEVTKKFMRDPIRIL 235 L SAT P V + + P I Sbjct: 182 LYSATFPLSVQKFMNSHLEKPYEIN 206 >2GXQ-A nrPDB Length = 207 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 70/207 (33%), Positives = 114/207 (55%), Gaps = 6/207 (2%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92 F D L +L ++ G P+ IQ A+ ++G D+I QA++GTGKT FA+ I + Sbjct: 2 EFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAE 61 Query: 93 QIELDL---KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQM 149 ++ + +ALVL PTRELA Q+ + A+ ++ A GGT + + L + Sbjct: 62 RLAPSQERGRKPRALVLTPTRELALQVASELTAVAPHL--KVVAVYGGTGYGKQKEAL-L 118 Query: 150 EAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQV 209 +V TPGR D L + L +++ VLDEADEMLS GF++++ + + Q Sbjct: 119 RGADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQT 178 Query: 210 VLLSATMPSDVLEVTKKFMRDPIRILV 236 +L SAT+PS + +++M++P+ I V Sbjct: 179 LLFSATLPSWAKRLAERYMKNPVLINV 205 >5H1Y-A nrPDB Length = 281 Score = 244 bits (622), Expect = 7e-65, Method: Composition-based stats. Identities = 66/241 (27%), Positives = 114/241 (47%), Gaps = 15/241 (6%) Query: 22 VIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTG 81 V + SF +M ++LRG+ G P+ IQ + I + G D+I A +G+G Sbjct: 42 VEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSG 101 Query: 82 KTATFAISIL-------QQIELDLK-ATQALVLAPTRELAQQIQKVVMALGDYMG----- 128 KT F + ++ +++ + L++ P+RELA+Q ++ + Sbjct: 102 KTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSP 161 Query: 129 -ASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEM 187 C CIGG +V+ +++ ++ H++V TPGR+ D+L ++ +S + LDEAD M Sbjct: 162 LLRCALCIGGMSVKEQMETIR-HGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRM 220 Query: 188 LSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIR 247 + GF+ I IF Q +L SATMP + K + P+ I V + + Sbjct: 221 IDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVI 280 Query: 248 Q 248 Q Sbjct: 281 Q 281 >5GVS-A nrPDB Length = 231 Score = 239 bits (609), Expect = 2e-63, Method: Composition-based stats. Identities = 65/230 (28%), Positives = 111/230 (48%), Gaps = 15/230 (6%) Query: 22 VIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTG 81 V + SF +M ++LRG+ G P+ IQ + I + G D+I A +G+G Sbjct: 3 VEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSG 62 Query: 82 KTATFAISIL-------QQIELDLK-ATQALVLAPTRELAQQIQKVVMALGDYMG----- 128 KT F + ++ +++ + L++ P+RELA+Q ++ + Sbjct: 63 KTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSP 122 Query: 129 -ASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEM 187 C CIGG +V+ +++ ++ H++V TPGR+ D+L ++ +S + LDEAD M Sbjct: 123 LLRCALCIGGMSVKEQMETIR-HGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRM 181 Query: 188 LSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVK 237 + GF+ I IF Q +L SATMP + K + P+ I V Sbjct: 182 IDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVG 231 >3BER-A nrPDB Length = 249 Score = 239 bits (609), Expect = 2e-63, Method: Composition-based stats. Identities = 71/227 (31%), Positives = 119/227 (52%), Gaps = 3/227 (1%) Query: 14 PDGMEP-EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDV 72 + P E E +F D+ +++ L G+ KP+ IQ AI ++G D+ Sbjct: 24 EEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDI 83 Query: 73 IAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCH 132 I A++G+GKT FA+ IL + + ALVL PTRELA QI + ALG +G Sbjct: 84 IGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSA 143 Query: 133 ACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEMLSRG 191 +GG + ++ L + PHII+ TPGR+ D L + + + +K V+DEAD +L+ Sbjct: 144 VIVGGIDSMSQSLAL-AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMD 202 Query: 192 FKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK 238 F+ ++ I + + + + L SATM V ++ + +++P++ V Sbjct: 203 FETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSS 249 >6AIC-A nrPDB Length = 214 Score = 238 bits (608), Expect = 3e-63, Method: Composition-based stats. Identities = 74/210 (35%), Positives = 126/210 (60%), Gaps = 3/210 (1%) Query: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90 + +F ++ +S++ ++ + + GF++P+ IQ+ +I ++G D++ QAQ+GTGKT F I + Sbjct: 1 MQNFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPL 60 Query: 91 LQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQME 150 ++++ + + Q+L+LAPTRELA Q+ + + G GG + +++ L+ + Sbjct: 61 IEKV-VGKQGVQSLILAPTRELAMQVAEQLREFSRGQGVQVVTVFGGMPIERQIKALK-K 118 Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNS-NTQV 209 P I+VGTPGRV D LNRR L I +LDEADEM++ GF D + I K+ + Q Sbjct: 119 GPQIVVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMMNMGFIDDMRFIMDKIPAVQRQT 178 Query: 210 VLLSATMPSDVLEVTKKFMRDPIRILVKKE 239 +L SATMP + + ++FM+ P I Sbjct: 179 MLFSATMPKAIQALVQQFMKSPKIIKTMNN 208 >3LY5-A nrPDB Length = 262 Score = 237 bits (605), Expect = 7e-63, Method: Composition-based stats. Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 13/230 (5%) Query: 13 GPDGMEPEGVIESNWNEIVDSFDDMNLS-------ESLLRGIYAYGFEKPSAIQQRAILP 65 PD E E + S + +F+D + + E+ L+ I GF + IQ ++I P Sbjct: 28 KPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRP 87 Query: 66 CIKGYDVIAQAQSGTGKTATFAISILQQIE----LDLKATQALVLAPTRELAQQIQKVVM 121 ++G D++A A++G+GKT F I ++ I + T L+L+PTRELA Q V+ Sbjct: 88 LLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTRELAMQTFGVLK 147 Query: 122 ALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFV 180 L + + +GG+N AE QKL +IIV TPGR+ D + K ++ V Sbjct: 148 ELMTHHVHTYGLIMGGSNRSAEAQKL-GNGINIIVATPGRLLDHMQNTPGFMYKNLQCLV 206 Query: 181 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRD 230 +DEAD +L GF++++ I + L + Q +L SAT V ++ + ++ Sbjct: 207 IDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQTRKVEDLARISLKK 256 >3FMO-B nrPDB Length = 300 Score = 234 bits (598), Expect = 5e-62, Method: Composition-based stats. Identities = 90/237 (37%), Positives = 134/237 (56%), Gaps = 10/237 (4%) Query: 10 RDNGPDGMEPEGVIESNWNEI---VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPC 66 R N D V++ + N V SF+++ L LL+G+YA GF +PS IQ+ A+ Sbjct: 67 RSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLM 126 Query: 67 I--KGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALG 124 + ++IAQ+QSGTGKTA F +++L Q+E K Q L L+PT ELA Q KV+ +G Sbjct: 127 LAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMG 186 Query: 125 DYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDE 183 + A N QK+ I++GTPG V D ++ +++ PK IK+FVLDE Sbjct: 187 KFYPELKLAYAVRGNKLERGQKISE---QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDE 243 Query: 184 ADEML-SRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKE 239 AD M+ ++G +DQ I + L N Q++L SAT V + +K + DP I +K+E Sbjct: 244 ADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 300 >3FHC-B nrPDB Length = 235 Score = 234 bits (597), Expect = 6e-62, Method: Composition-based stats. Identities = 89/234 (38%), Positives = 133/234 (56%), Gaps = 10/234 (4%) Query: 15 DGMEPEGVIESNWNEI---VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCI--KG 69 D V++ + N V SF+++ L LL+G+YA GF +PS IQ+ A+ + Sbjct: 5 DNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPP 64 Query: 70 YDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGA 129 ++IAQ+QSGTGKTA F +++L Q+E K Q L L+PT ELA Q KV+ +G + Sbjct: 65 QNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPE 124 Query: 130 SCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEML 188 A N QK+ I++GTPG V D ++ +++ PK IK+FVLDEAD M+ Sbjct: 125 LKLAYAVRGNKLERGQKISE---QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMI 181 Query: 189 -SRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241 ++G +DQ I + L N Q++L SAT V + +K + DP I +K+EE Sbjct: 182 ATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE 235 >3IUY-A nrPDB Length = 228 Score = 228 bits (581), Expect = 4e-60, Method: Composition-based stats. Identities = 64/216 (29%), Positives = 103/216 (47%), Gaps = 9/216 (4%) Query: 28 NEIVDSFDD-MNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATF 86 + F D LL+ I G KP+ IQ +A ++G D+I AQ+GTGKT ++ Sbjct: 15 PKPTCRFKDAFQQYPDLLKSIIRVGILKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSY 74 Query: 87 AISILQQIELDL------KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNV 140 + ++ LVL PTRELA ++ Y G GG N Sbjct: 75 LMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYS-YKGLKSICIYGGRNR 133 Query: 141 RAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIF 200 +++ + + II+ TPGR+ D+ ++ + I V+DEAD+ML F+ QI I Sbjct: 134 NGQIEDI-SKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL 192 Query: 201 QKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILV 236 + + Q V+ SAT P V ++ +++DP+ + V Sbjct: 193 LDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYV 228 >2KBE-A nrPDB Length = 226 Score = 226 bits (575), Expect = 2e-59, Method: Composition-based stats. Identities = 79/225 (35%), Positives = 129/225 (57%), Gaps = 8/225 (3%) Query: 17 MEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIK--GYDVIA 74 + ++ SFD++ L+ LL+GIYA F+KPS IQ+RA+ + ++IA Sbjct: 7 LADIQADPNSPLYSAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIA 66 Query: 75 QAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHAC 134 Q+QSGTGKTA F++++L ++ + + QA+ LAP+RELA+Q +VV +G + + Sbjct: 67 QSQSGTGKTAAFSLTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLI 126 Query: 135 IGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLS-RGFK 193 + +K + +IVGTPG V D++ R+ + + IK+FVLDEAD ML +G Sbjct: 127 V-----PDSFEKNKQINAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLG 181 Query: 194 DQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK 238 DQ + + L +TQ+VL SAT V + KK + + + ++ Sbjct: 182 DQCIRVKRFLPKDTQLVLFSATFADAVRQYAKKIVPNANTLELQT 226 >1Q0U-A nrPDB Length = 219 Score = 222 bits (567), Expect = 2e-58, Method: Composition-based stats. Identities = 66/207 (31%), Positives = 113/207 (54%), Gaps = 5/207 (2%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F ++ I F KP+ IQ+R I ++G ++ Q+Q+GTGKT + + I+++ Sbjct: 6 FTRFPFQPFIIEAIKTLRFYKPTEIQERIIPGALRGESMVGQSQTGTGKTHAYLLPIMEK 65 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMG----ASCHACIGGTNVRAEVQKLQM 149 I+ + QA++ APTRELA QI + + + IGGT+ + ++KL + Sbjct: 66 IKPERAEVQAVITAPTRELATQIYHETLKITKFCPKDRMIVARCLIGGTDKQKALEKLNV 125 Query: 150 EAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQV 209 + PHI++GTPGR+ D + + L + V+DEAD ML GF + I ++ + Q+ Sbjct: 126 Q-PHIVIGTPGRINDFIREQALDVHTAHILVVDEADLMLDMGFITDVDQIAARMPKDLQM 184 Query: 210 VLLSATMPSDVLEVTKKFMRDPIRILV 236 ++ SAT+P + KK+M +P + V Sbjct: 185 LVFSATIPEKLKPFLKKYMENPTFVHV 211 >2PL3-A nrPDB Length = 236 Score = 222 bits (566), Expect = 2e-58, Method: Composition-based stats. Identities = 64/220 (29%), Positives = 114/220 (51%), Gaps = 8/220 (3%) Query: 26 NWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTAT 85 N NEI F D LS+ L+G+ + + IQ++ I ++G DV+ A++G+GKT Sbjct: 20 NVNEITR-FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLA 78 Query: 86 FAISILQQIE----LDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVR 141 F + +L+ + L+++PTRELA Q +V+ +G S IGG +++ Sbjct: 79 FLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 138 Query: 142 AEVQKLQMEAPHIIVGTPGRVFDMLNRRY-LSPKYIKMFVLDEADEMLSRGFKDQIYDIF 200 E +++ +I+V TPGR+ ++ ++M VLDEAD +L GF D + + Sbjct: 139 HEAERI--NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVI 196 Query: 201 QKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240 + L Q +L SAT V ++ + +++P + V ++ Sbjct: 197 ENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKA 236 >2OXC-A nrPDB Length = 230 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 86/207 (41%), Positives = 130/207 (62%), Gaps = 4/207 (1%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93 F+ + LS +L G+ A GFE+PS +Q +AI G D+I QA+SGTGKT F+ L Sbjct: 26 FESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDS 85 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAP 152 + L+ +TQ L+LAPTRE+A QI V+ A+G M G CH IGGT + + K +++ Sbjct: 86 LVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQD--KTRLKKC 143 Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRG-FKDQIYDIFQKLNSNTQVVL 211 HI VG+PGR+ ++ YL+P I++F+LDEAD++L G F++QI I+ L ++ Q++ Sbjct: 144 HIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLA 203 Query: 212 LSATMPSDVLEVTKKFMRDPIRILVKK 238 +SAT P + K+MRDP + + Sbjct: 204 VSATYPEFLANALTKYMRDPTFVRLNS 230 >5V9X-A nrPDB Length = 877 Score = 213 bits (543), Expect = 1e-55, Method: Composition-based stats. Identities = 86/441 (19%), Positives = 165/441 (37%), Gaps = 73/441 (16%) Query: 35 DDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKT-ATFAISI--- 90 D + +L R + F P+ Q A +G + + A +G+GKT A F +I Sbjct: 28 DPLGRFSALTREWFTTAFAAPTPAQADAWSAISEGNNTLVIAPTGSGKTLAAFLWAIDRL 87 Query: 91 LQQIELDLKATQALVLAPTRELAQQIQK-------VVMALGDYMGASCHACIG----GTN 139 + TQ L ++P + LA +++ + + + G + G Sbjct: 88 ADPAREPSQGTQVLYVSPLKALAVDVERNLRTPLTGITRVAERHGLPAPSITVGVRSGDT 147 Query: 140 VRAEVQKLQMEAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEML--SRG--FKD 194 + + + P +++ TP +F ML + + ++ ++DE + RG Sbjct: 148 PPNQRRAMIANPPDVLITTPESLFLMLTSAARETLTSVRTVIVDEVHAVAATKRGAHLAL 207 Query: 195 QIYDIFQKLNSNTQVVLLSATM--PSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYI- 251 + + Q L++ Q + LSAT+ P +V + P I+ T + Q + Sbjct: 208 SLERLDQLLDTPAQRIGLSATVRPPEEVARFLSG--QAPTTIVCPPAAKTFDLSVQVPVP 265 Query: 252 ---NVEREEWKLDT---LCDLYETLTITQAVIFINTRRKVDWLTEKMH------------ 293 N++ D + DL E +++F N+RR + LT +++ Sbjct: 266 DMANLDNNSIWPDVEERIVDLVEAH--NSSIVFANSRRLAERLTSRLNEIHAERSGIELP 323 Query: 294 -----------------------ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330 A A HG + +++R + + +SG R ++ T Sbjct: 324 AGPNPEVGGGAPAHLMGSGQANGAPPLLARAHHGSVSKEQRAQVEDDLKSGRLRAVVATS 383 Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGG-RFGRKGVAINMVTEED--KRTLRDI 387 L GID+ V LVI + P + + + R+GR G + G + + Sbjct: 384 SLELGIDMGAVDLVIQVEAPPSVASGLQRVGRAGHQVGEISQGVLFPKHRTDLIGCAVTV 443 Query: 388 ETFYNTSIE--EMPLNVADLI 406 + IE +P N D++ Sbjct: 444 QRMQTGDIETLRVPANPLDVL 464 >3DKP-A nrPDB Length = 245 Score = 210 bits (536), Expect = 7e-55, Method: Composition-based stats. Identities = 61/237 (25%), Positives = 114/237 (48%), Gaps = 11/237 (4%) Query: 16 GMEPEGVIESNWNEIVDSFD----DMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYD 71 V ++ + + +F + ++ LL+ I GF+ P+ IQ +AI + G + Sbjct: 9 NKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRE 68 Query: 72 VIAQAQSGTGKTATFAISILQQIE-LDLKATQALVLAPTRELAQQIQKVVMALGDYMGAS 130 ++A A +G+GKT F+I IL Q++ K +AL+++PTRELA QI + ++ + + G Sbjct: 69 LLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFR 128 Query: 131 CHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR--RYLSPKYIKMFVLDEADEML 188 H + + I+V TP R+ +L + + ++ V+DE+D++ Sbjct: 129 IHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLF 188 Query: 189 S---RGFKDQIYDIFQKLNSNT-QVVLLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241 GF+DQ+ IF S+ + + SAT DV + K + + I + + Sbjct: 189 EDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNS 245 >4Q48-A nrPDB Length = 525 Score = 209 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 63/350 (18%), Positives = 119/350 (34%), Gaps = 16/350 (4%) Query: 42 SLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKAT 101 LL+ I+ G+ +Q + +G + + +G GK+ + + L L+ Sbjct: 14 HLLQTIW--GYPAFRGVQGEIVQQVAEGGNALVLMPTGGGKSLCYQLPSL------LRPG 65 Query: 102 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 161 +V++P L + + G + R L ++ P R Sbjct: 66 TGIVVSPLIALMKDQVDTLRQNGVRAAFLNSTLLP-HEAREVEDALLRGDLDLLYVAPER 124 Query: 162 VFDMLNRRYLSPKYIKMFVLDEADEMLSRG--FKDQIYD--IFQKLNSNTQVVLLSATMP 217 + L + +F +DEA + G F+ + + + V L+AT Sbjct: 125 LLMPRTLDLLERAPVALFAIDEAHCVSQWGHDFRPEYQQLSVLAERFPELPRVALTATAD 184 Query: 218 SDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVI 277 K +R I+ ++ K L + E ++ Sbjct: 185 ERTRADIKSVLR-LEDAPQFVSSFDRPNIQYRVGL--KDSPKTQLLHFIREEHPGDAGIV 241 Query: 278 FINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGID 337 + +R+ V+ + + A+ A H + ER+ + F + ++ T GID Sbjct: 242 YCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLNEEGVIVCATVAFGMGID 301 Query: 338 VQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387 V V + DLP + E Y GR GR G A + D +R + Sbjct: 302 KPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTAWMVYGLSDVVNVRRM 351 >5LBA-B nrPDB Length = 445 Score = 203 bits (517), Expect = 1e-52, Method: Composition-based stats. Identities = 70/380 (18%), Positives = 141/380 (37%), Gaps = 39/380 (10%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKG-YDVIAQAQSGTGKTATFAISIL 91 S D S L+ ++ + K + +Q+ A + +KG DV +G GK+ + + L Sbjct: 1 SMDPERRVRSTLKKVFGFDSFK-TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL 59 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEA 151 L +V++P L Q ++ L +S ++ + + + L+ E Sbjct: 60 ------LAKGITIVVSPLIALIQDQVDHLLTL-KVRVSSLNSKLSAQERKELLADLEREK 112 Query: 152 PH--IIVGTPG---------RVFDMLNRRYLSPKYIKMFVLDEADEMLSRG--FKDQIYD 198 P I+ TP + +++R LS V+DEA + G F+ Sbjct: 113 PQTKILYITPEMAASSSFQPTLNSLVSRHLLS-----YLVVDEAHCVSQWGHDFRPDYLR 167 Query: 199 IFQKLNS--NTQVVLLSATMPSDVLE--VTKKFMRDPIRIL---VKKEELTLEGIRQFYI 251 + + + V L+AT V E ++ P+ I + L + ++ + Sbjct: 168 LGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYD-VQFKEL 226 Query: 252 NVEREEW-KLDTLCDLYETLTITQ---AVIFINTRRKVDWLTEKMHARDFTVSAMHGDMD 307 + K L L + +++ TR + L ++ R A H + Sbjct: 227 ISDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLK 286 Query: 308 QKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFG 367 ER ++ ++ V++ T G+D V V ++++ + Y GR GR G Sbjct: 287 ASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDG 346 Query: 368 RKGVAINMVTEEDKRTLRDI 387 + + D+ + + Sbjct: 347 KPSWCRLYYSRNDRDQVSFL 366 >5LB8-A nrPDB Length = 518 Score = 203 bits (517), Expect = 1e-52, Method: Composition-based stats. Identities = 70/380 (18%), Positives = 141/380 (37%), Gaps = 39/380 (10%) Query: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKG-YDVIAQAQSGTGKTATFAISIL 91 S D S L+ ++ + K + +Q+ A + +KG DV +G GK+ + + L Sbjct: 1 SMDPERRVRSTLKKVFGFDSFK-TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL 59 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEA 151 L +V++P L Q ++ L +S ++ + + + L+ E Sbjct: 60 ------LAKGITIVVSPLIALIQDQVDHLLTL-KVRVSSLNSKLSAQERKELLADLEREK 112 Query: 152 PH--IIVGTPG---------RVFDMLNRRYLSPKYIKMFVLDEADEMLSRG--FKDQIYD 198 P I+ TP + +++R LS V+DEA + G F+ Sbjct: 113 PQTKILYITPEMAASSSFQPTLNSLVSRHLLS-----YLVVDEAHCVSQWGHDFRPDYLR 167 Query: 199 IFQKLNS--NTQVVLLSATMPSDVLE--VTKKFMRDPIRIL---VKKEELTLEGIRQFYI 251 + + + V L+AT V E ++ P+ I + L + ++ + Sbjct: 168 LGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYD-VQFKEL 226 Query: 252 NVEREEW-KLDTLCDLYETLTITQ---AVIFINTRRKVDWLTEKMHARDFTVSAMHGDMD 307 + K L L + +++ TR + L ++ R A H + Sbjct: 227 ISDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLK 286 Query: 308 QKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFG 367 ER ++ ++ V++ T G+D V V ++++ + Y GR GR G Sbjct: 287 ASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDG 346 Query: 368 RKGVAINMVTEEDKRTLRDI 387 + + D+ + + Sbjct: 347 KPSWCRLYYSRNDRDQVSFL 366 >2WWY-A nrPDB Length = 591 Score = 202 bits (513), Expect = 3e-52, Method: Composition-based stats. Identities = 67/378 (17%), Positives = 141/378 (37%), Gaps = 37/378 (9%) Query: 41 ESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKA 100 + +L+ ++ EK +Q I + G +V +G GK+ + + L Sbjct: 33 KDILQNVFK--LEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPAL------CSD 84 Query: 101 TQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPH------I 154 LV+ P L + V+ LG + ++ + V+ + E + + Sbjct: 85 GFTLVICPLISLMEDQLMVLKQLGI-----SATMLNASSSKEHVKWVHAEMVNKNSELKL 139 Query: 155 IVGTPGRV------FDMLNRRYLSPKYIKMFVLDEADEMLSRG--FKDQIYD--IFQKLN 204 I TP ++ L + Y + ++ ++ V DE G F+ I ++ Sbjct: 140 IYVTPEKIAKSKMFMSRLEKAYEARRFTRIAV-DEVHCCSQWGHDFRPDYKALGILKRQF 198 Query: 205 SNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEG----IRQFYINVEREEWKL 260 N ++ L+AT + VL +K + + +RQ N E + Sbjct: 199 PNASLIGLTATATNHVLTDAQKILC-IEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDI 257 Query: 261 DTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRS 320 L + +I+ +++ + +T + A H +++ +++ + R++ + Sbjct: 258 VKLINGRYKGQ--SGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSA 315 Query: 321 GSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEED 380 +V++ T GID V VI++ + + ENY GR GR K I D Sbjct: 316 NEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGD 375 Query: 381 KRTLRDIETFYNTSIEEM 398 + + N +++ Sbjct: 376 IFRISSMVVMENVGQQKL 393 >5AGA-A nrPDB Length = 830 Score = 197 bits (501), Expect = 7e-51, Method: Composition-based stats. Identities = 85/440 (19%), Positives = 168/440 (38%), Gaps = 107/440 (24%) Query: 36 DMNLSESLLRGIYAYGFEKPSAIQQRAIL--PCIKGYDVIAQAQSGTGKTATFAISILQQ 93 + L +++L +++G +K Q +L ++G +++ A + GKT + IL++ Sbjct: 9 NWGLPKAVLEKYHSFGVKKMFEWQAECLLLGQVLEGKNLVYSAPTSAGKTLVAELLILKR 68 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPH 153 + K +AL + P +A++ + + +L +G +G T+ L Sbjct: 69 VLEMRK--KALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSL-----D 121 Query: 154 IIVGTPGRVFDMLNRRYLSPK--YIKMFVLDEADEMLS---RGFKDQI------------ 196 I V T R ++NR K + M V+DE ML RG+ ++ Sbjct: 122 IAVCTIERANGLINRLIEENKMDLLGMVVVDELH-MLGDSHRGYLLELLLTKICYITRKS 180 Query: 197 ----YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIR----- 247 D+ L++ Q+V +SAT+P+ LE+ ++ + + LE ++ Sbjct: 181 ASCQADLASSLSNAVQIVGMSATLPN--LELVASWLNAELYHTDFRPVPLLESVKVGNSI 238 Query: 248 -----------QFYINVEREEWKLDTLCDLYETLTITQAV-IFINTRRKVDWLTEKMHAR 295 + + V+ +E + +LC YET+ +V +F +++ + L + + Sbjct: 239 YDSSMKLVREFEPMLQVKGDEDHVVSLC--YETICDNHSVLLFCPSKKWCEKLADIIARE 296 Query: 296 DFT-------------------------------------------------VSAMHGDM 306 + V+ H + Sbjct: 297 FYNLHHQAEGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGL 356 Query: 307 DQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTNRENYIHRIGR 362 +ERD+I FR G RVL T L+ G+++ ++I + P + Y +GR Sbjct: 357 TFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGR 416 Query: 363 GGRFG--RKGVAINMVTEED 380 GR G G +I + + Sbjct: 417 AGRKGVDTVGESILICKNSE 436 >2P6R-A nrPDB Length = 702 Score = 139 bits (351), Expect = 2e-33, Method: Composition-based stats. Identities = 74/386 (19%), Positives = 139/386 (36%), Gaps = 60/386 (15%) Query: 47 IYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVL 106 + G E+ Q A+ G +++ + GKT ++ + + +K ++L + Sbjct: 18 LKEEGIEELFPPQAEAVEKVFSGKNLLLAMPTAAGKTL---LAEMAMVREAIKGGKSLYV 74 Query: 107 APTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDML 166 P R LA + + + +G G R E + IIV T + ++ Sbjct: 75 VPLRALAGEKYESFKKW-EKIGLRIGISTGDYESRDE----HLGDCDIIVTTSEKADSLI 129 Query: 167 NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDI----FQKLNSNTQVVLLSATMPSDVLE 222 R K + V+DE +L + +I +++N +V+ LSAT P+ V E Sbjct: 130 RNRASWIKAVSCLVVDEIH-LLDSEKRGATLEILVTKMRRMNKALRVIGLSATAPN-VTE 187 Query: 223 VTKKFMRDPI----RILVKKEELTLEGIRQFY--INVEREEWKLDTLCDLYETLTITQAV 276 + + D R + E + EG + + K + L + + Sbjct: 188 IAEWLDADYYVSDWRPVPLVEGVLCEGTLELFDGAFSTSRRVKFEELVEEC-VAENGGVL 246 Query: 277 IFINTRRKVDWLTEKMHA--------RDF----------------------TVSAMHGDM 306 +F +TRR + K+ A + H + Sbjct: 247 VFESTRRGAEKTAVKLSAITAKYVENEGLEKAILEENEGEMSRKLAECVRKGAAFHHAGL 306 Query: 307 DQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVIN-------YDLPTNRENYIHR 359 +R V+ FR G+ +V++ T LA G+++ +++ Y Y Sbjct: 307 LNGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPARRVIVRSLYRFDGYSKRIKVSEYKQM 366 Query: 360 IGRGGRFG--RKGVAINMVTEEDKRT 383 GR GR G +G AI +V + D+ Sbjct: 367 AGRAGRPGMDERGEAIIIVGKRDREI 392 >1GM5-A nrPDB Length = 780 Score = 132 bits (333), Expect = 2e-31, Method: Composition-based stats. Identities = 63/336 (18%), Positives = 131/336 (38%), Gaps = 35/336 (10%) Query: 68 KGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYM 127 K + + Q G+GKT ++IL E Q + PT LA Q + + Sbjct: 388 KPMNRLLQGDVGSGKTVVAQLAILDNYEA---GFQTAFMVPTSILAIQHYRRTVESFSKF 444 Query: 128 GASCHACIGGTNVRAEVQ---KLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEA 184 IG T + + L+ +++GT ++ + K + + ++DE Sbjct: 445 NIHVALLIGATTPSEKEKIKSGLRNGQIDVVIGT----HALIQED-VHFKNLGLVIIDEQ 499 Query: 185 DEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLE 244 F + + +++SAT + F D ++ + + Sbjct: 500 HR-----FGVKQREALMNKGKMVDTLVMSAT--PIPRSMALAFYGDLDVTVIDEMPPGRK 552 Query: 245 GIRQFYINVEREEWKLDTLCDLYETLTITQA-VIF----------INTRRKVDWLTEKMH 293 ++ + ++R + + E + QA +++ + + ++ K Sbjct: 553 EVQTMLVPMDRVNEVYEFVRQ--EVMRGGQAFIVYPLIEESDKLNVKSAVEMYEYLSKEV 610 Query: 294 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 353 +F + MHG + Q+E+D +M EF G +L++T ++ GIDV + ++++ + Sbjct: 611 FPEFKLGLMHGRLSQEEKDRVMLEFAEGRYDILVSTTVIEVGIDVPRANVMVIENPERFG 670 Query: 354 ENYIH----RIGRGGRFGRKGVAINMVTEEDKRTLR 385 +H R+GRGG+ + + V EE LR Sbjct: 671 LAQLHQLRGRVGRGGQEAYCFLVVGDVGEEAMERLR 706 >2ZJ8-A nrPDB Length = 720 Score = 129 bits (325), Expect = 2e-30, Method: Composition-based stats. Identities = 65/379 (17%), Positives = 142/379 (37%), Gaps = 59/379 (15%) Query: 35 DDMNLSESLLRGIYAYGFEKPSAIQQRAILP-CIKGYDVIAQAQSGTGKTATFAISILQQ 93 D++ + E + + G E Q A+ ++G + + + +GKT I+++ + Sbjct: 4 DELRVDERIKSTLKERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAMVHR 63 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPH 153 I + +A+ + P + LA++ + + +G G + + E + Sbjct: 64 IL--TQGGKAVYIVPLKALAEEKFQEFQDW-EKIGLRVAMATGDYDSKDEW----LGKYD 116 Query: 154 IIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLS 213 II+ T + +L K +K+ V DE + SR + I + Q++ LS Sbjct: 117 IIIATAEKFDSLLRHGSSWIKDVKILVADEIHLIGSRDRGATLEVILAHMLGKAQIIGLS 176 Query: 214 ATM--PSDVLEV--TKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYET 269 AT+ P ++ E + + D + +++ + F + + + +L Sbjct: 177 ATIGNPEELAEWLNAELIVSDWRPVKLRRGVF----YQGFVTWEDGSIDRFSSWEELVYD 232 Query: 270 LTITQ--AVIFINTRRKVDWLTEKMHAR-------------------------------- 295 + A+IF+N RRK + + ++ + Sbjct: 233 AIRKKKGALIFVNMRRKAERVALELSKKVKSLLTKPEIRALNELADSLEENPTNEKLAKA 292 Query: 296 -DFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVIN-------Y 347 V+ H + + ER ++ FR G + ++ T L+ GI+ ++I + Sbjct: 293 IRGGVAFHHAGLGRDERVLVEENFRKGIIKAVVATPTLSAGINTPAFRVIIRDIWRYSDF 352 Query: 348 DLPTNRENYIH-RIGRGGR 365 + +H +GR GR Sbjct: 353 GMERIPIIEVHQMLGRAGR 371 >2VA8-A nrPDB Length = 715 Score = 127 bits (320), Expect = 7e-30, Method: Composition-based stats. Identities = 68/431 (15%), Positives = 153/431 (35%), Gaps = 70/431 (16%) Query: 35 DDMNLSESLLRGIYAYGFEKPSAIQQRAIL-PCIKGYDVIAQAQSGTGKTATFAISILQQ 93 +D+ L +++ I G +K + Q A+ ++G ++ + +G+GKT + I+ Sbjct: 11 EDLKLPSNVIEIIKKRGIKKLNPPQTEAVKKGLLEGNRLLLTSPTGSGKTLIAEMGIISF 70 Query: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPH 153 + +A+ + P R L + + + + +G G + K Sbjct: 71 LL--KNGGKAIYVTPLRALTNE-KYLTFKDWELIGFKVAMTSGDYDTDDAWLK----NYD 123 Query: 154 IIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLS 213 II+ T ++ + R + FVLDE + + + ++ LS Sbjct: 124 IIITTYEKLDSLWRHRPEWLNEVNYFVLDELHYLNDPERGPVVESV-TIRAKRRNLLALS 182 Query: 214 ATMP--SDVLEV--TKKFMRD--PIRILVKKEELTLEGIRQFYINVEREEWKLD----TL 263 AT+ + + + + P+ ++ + I + K+ + Sbjct: 183 ATISNYKQIAKWLGAEPVATNWRPVPLIEGVIYPERKKKEYNVIFKDNTTKKVHGDDAII 242 Query: 264 CDLYETLTIT-QAVIFINTRRKVDWLTEKM-HARDF------------------------ 297 ++L+ Q ++F N+R+ + K+ + +F Sbjct: 243 AYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDENALSEILKQLDDIEEGGSD 302 Query: 298 -----------TVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVI- 345 V+ H + + RD+I FR +V++ T LA G+++ +++I Sbjct: 303 EKELLKSLISKGVAYHHAGLSKALRDLIEEGFRQRKIKVIVATPTLAAGVNLPARTVIIG 362 Query: 346 -NYDLPTNRENYI---------HRIGRGGRFG--RKGVAINMVTEEDKRTLRDIETFYNT 393 Y Y GR GR G + G +I +V +++ R + + + Sbjct: 363 DIYRFNKKIAGYYDEIPIMEYKQMSGRAGRPGFDQIGESIVVVRDKED-VDRVFKKYVLS 421 Query: 394 SIEEMPLNVAD 404 +E + + Sbjct: 422 DVEPIESKLGS 432 >1WP9-A nrPDB Length = 494 Score = 110 bits (274), Expect = 1e-24, Method: Composition-based stats. Identities = 44/187 (23%), Positives = 79/187 (42%), Gaps = 30/187 (16%) Query: 223 VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDL----YETLTITQAVIF 278 + K M+ I +LV+ +E+ L+ K+D L ++ + ++ ++F Sbjct: 320 FSDKRMKKAISLLVQAKEIGLD------------HPKMDKLKEIIREQLQRKQNSKIIVF 367 Query: 279 INTRRKVDWLTEKMHARDFTVSAMHG--------DMDQKERDVIMREFRSGSSRVLITTD 330 N R + ++ G + Q+E+ +I+ EF G VL+ T Sbjct: 368 TNYRETAKKIVNELVKDGIKAKRFVGQASKENDRGLSQREQKLILDEFARGEFNVLVATS 427 Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETF 390 + G+DV +V LV+ Y+ + I R GR GR V I M + RD E + Sbjct: 428 VGEEGLDVPEVDLVVFYEPVPSAIRSIQRRGRTGRHMPGRVIILM-----AKGTRD-EAY 481 Query: 391 YNTSIEE 397 Y +S ++ Sbjct: 482 YWSSRQK 488 Score = 68.1 bits (165), Expect = 7e-12, Method: Composition-based stats. Identities = 43/212 (20%), Positives = 82/212 (38%), Gaps = 6/212 (2%) Query: 58 IQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQ 117 I Q I K + + +G GKT ++ + L + L+LAPT+ L Q Sbjct: 12 IYQEVIYAKCKETNCLIVLPTGLGKTLIAM--MIAEYRLTKYGGKVLMLAPTKPLVLQHA 69 Query: 118 KVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIK 177 + L + A G + + +IV TP + + L +S + + Sbjct: 70 ESFRRLFNLPPEKIVALTGEKSPEERSKA--WARAKVIVATPQTIENDLLAGRISLEDVS 127 Query: 178 MFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVK 237 + V DEA + I +++ N V+ L+A+ S ++ + I + Sbjct: 128 LIVFDEAHRAVGNYAYVFIAREYKRQAKNPLVIGLTASPGSTPEKIMEVINNLGIEHIEY 187 Query: 238 KEELTLEGIRQFYINVEREEWKLDTLCDLYET 269 + E + + + Y+ R EW L ++Y+ Sbjct: 188 RSENSPD--VRPYVKGIRFEWVRVDLPEIYKE 217 >5TNU-A nrPDB Length = 459 Score = 101 bits (253), Expect = 4e-22, Method: Composition-based stats. Identities = 62/386 (16%), Positives = 139/386 (36%), Gaps = 98/386 (25%) Query: 59 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 118 Q A+ +K I +G GKT A+ I+ ++ L++ PT +L Q ++ Sbjct: 93 QAEAVKAWLKEKRGIIVLPTGAGKTQV-ALKIVSIMK-----VATLIVVPTIDLITQWKE 146 Query: 119 VVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKM 178 + Y+ GG + + + ++ + R ++ N+ + Sbjct: 147 ---RINKYLDFDPGIIGGGEDSLKGITVITYDSAY------TRAEELGNK-------FPL 190 Query: 179 FVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSAT-------------------MPSD 219 + DE + S G+ I +L ++ + L+AT Sbjct: 191 LIFDEVHHLPSEGY-----SIMAQLFASPYRLGLTATPERDDGKHELYPILVGPIVYRKS 245 Query: 220 VLEVTKKF-----------------------MRDPIRILVKKEELTLEGIRQFYINVE-- 254 V E+ K+ +R ++ + L L+ + F+ V+ Sbjct: 246 VEELAGKYIAKYKIKKLYVSLTNEEKKRYDGLRKKLKDFLSSRGLKLQNLDDFHRLVKLA 305 Query: 255 ---------------------REEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH 293 + K++ L ++ + + ++F + + Sbjct: 306 AKDKEAREALLAWHESLNIAVNSQSKIEKLREILQEYKNEKIIVFTRDTQMAYRI----- 360 Query: 294 ARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 353 ++ F + + D+ ER+ I+++FR G RV++ + + G+DV +L I + Sbjct: 361 SKTFLIPVVTYKTDKDEREEILQKFRDGEYRVIVASTVFDEGVDVPDATLAIVMGGYGTK 420 Query: 354 ENYIHRIGRGGRFG-RKGVAINMVTE 378 ++ R+GR R ++ + I +VT+ Sbjct: 421 RQFLQRLGRILRKKDKEALLIEIVTK 446 >6G19-A nrPDB Length = 696 Score = 100 bits (249), Expect = 1e-21, Method: Composition-based stats. Identities = 35/167 (20%), Positives = 65/167 (38%), Gaps = 17/167 (10%) Query: 249 FYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKV----DWLTEKMHARDFTVSAMH- 303 Y N + + + L + ++ +IF TR+ W+ E + V A H Sbjct: 371 KYENEKLIKLRNTILEQFTRSEESSRGIIFTKTRQSTYALSQWIMENAKFAEVGVKAHHL 430 Query: 304 ---------GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRE 354 M Q E+ ++ +FR+G +LI T + G+D+++ ++VI Y L TN Sbjct: 431 IGAGHSSEVKPMTQTEQKEVISKFRTGEINLLIATTVAEEGLDIKECNIVIRYGLVTNEI 490 Query: 355 NYIHRIGRGGRFGRKGVAINMVTE--EDKRTLRDI-ETFYNTSIEEM 398 + GR V + ++ + D E +I + Sbjct: 491 AMVQARGRARADESTYVLVTSSGSGVTEREIVNDFREKMMYKAINRV 537 Score = 51.9 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 23/146 (15%), Positives = 53/146 (36%), Gaps = 22/146 (15%) Query: 56 SAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI---LQQIELDLKATQALVLAPTREL 112 Q P + G ++I +G+GKT L + + ++ + +VL L Sbjct: 4 RPYQMEVAQPALDGKNIIICLPTGSGKTRVAVYITKDHLDKKKQASESGKVIVLVNKVML 63 Query: 113 AQQIQKVVMALGDYMG--ASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRY 170 A+Q+ + Y+ G T ++ ++ +++ +I+ T +L Sbjct: 64 AEQLFR--KEFNPYLKKWYRIIGLSGDTQLKISFPEV-VKSYDVIIST----AQILENSL 116 Query: 171 LSPKY----------IKMFVLDEADE 186 L+ + + ++DE Sbjct: 117 LNLESGDDDGVQLSDFSLIIIDECHH 142 >4GL2-A nrPDB Length = 699 Score = 97.7 bits (242), Expect = 9e-21, Method: Composition-based stats. Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 14/131 (10%) Query: 250 YINVEREEWKLDTLCDLYETLTITQAVIFINTRRKV----DWLTEKMHARDFTVSAMH-- 303 Y N + + + + T + +IF TR+ W+TE + V A H Sbjct: 378 YENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLI 437 Query: 304 --------GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNREN 355 M Q E+ ++ +FR+G +LI T + G+D+++ ++VI Y L TN Sbjct: 438 GAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIA 497 Query: 356 YIHRIGRGGRF 366 + GR Sbjct: 498 MVQARGRARAD 508 Score = 53.8 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 37/255 (14%), Positives = 84/255 (32%), Gaps = 40/255 (15%) Query: 56 SAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLK---ATQALVLAPTREL 112 Q P ++G ++I +G GKT ++ K + +VL L Sbjct: 9 RPYQMEVAQPALEGKNIIICLPTGCGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLL 68 Query: 113 AQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTP----GRVFDMLNR 168 +Q+ + G T ++ ++ +++ II+ T + ++ N Sbjct: 69 VEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEV-VKSCDIIISTAQILENSLLNLENG 127 Query: 169 R--YLSPKYIKMFVLDEADEMLSRGFKDQIYD--IFQKLNSNT------------QVVLL 212 + + ++DE + I + QKL +N Q++ L Sbjct: 128 EDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIPLPQILGL 187 Query: 213 S-------ATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIR-QFYINVER--------E 256 + AT + E K + +K + L+ ++ Q ++ E Sbjct: 188 TASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKFAIADATRE 247 Query: 257 EWKLDTLCDLYETLT 271 + + L ++ + Sbjct: 248 DPFKEKLLEIMTRIQ 262 >5JCF-A nrPDB Length = 701 Score = 97.0 bits (240), Expect = 1e-20, Method: Composition-based stats. Identities = 40/184 (21%), Positives = 71/184 (38%), Gaps = 28/184 (15%) Query: 244 EGIRQFYINVEREEWKL----DTLCDLYETLTITQAVIFINTRRKV----DWLTEKMHAR 295 + +++ E + KL +TL + + + +IF TR+ W+ + Sbjct: 367 KQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFE 426 Query: 296 DFTVSAM----------HGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVI 345 + + A M Q E+ ++ +FR GS +LI T + G+D+++ ++VI Sbjct: 427 EVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVI 486 Query: 346 NYDLPTNRENYIHRIGRGGRFGRKGVAINM-----VTEEDKRTLRDIETFYNTSI---EE 397 Y L TN + GR + V ED R E +I +E Sbjct: 487 RYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFR--ENMMYKAIRRVQE 544 Query: 398 MPLN 401 MP Sbjct: 545 MPPE 548 Score = 44.2 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 24/179 (13%), Positives = 58/179 (32%), Gaps = 25/179 (13%) Query: 59 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLK---ATQALVLAPTRELAQQ 115 Q P + G ++I +G+GKT ++ K + +VL L +Q Sbjct: 12 QMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQ 71 Query: 116 -IQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTP-----GRVFDMLNRR 169 ++K + G + ++ ++ ++ +I+ T + Sbjct: 72 HLRKEFNPFLKHW-YQVIGLSGDSELKISFPEV-VKRYDVIICTAQILENSLLNATEEDE 129 Query: 170 YLSPKYIKMFVLDEADEMLSRGFKDQIYDIF--------------QKLNSNTQVVLLSA 214 + + ++D+ G + I + + L Q++ L+A Sbjct: 130 SVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKENKPLIPQPQILGLTA 188 >1D9Z-A nrPDB Length = 657 Score = 94.6 bits (234), Expect = 7e-20, Method: Composition-based stats. Identities = 54/281 (19%), Positives = 104/281 (37%), Gaps = 49/281 (17%) Query: 158 TPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV---LLSA 214 TP + D +L ++DE+ L Q+ ++ + QV+ Sbjct: 320 TPYTLLDYFPDDFL-------IIVDESHVTL-----PQLRGMYNGDRARKQVLVDHGFRL 367 Query: 215 TMPSDVLEVT-KKFMRDPIRILVKKEELTLEGIRQFY----------------INVEREE 257 D +T ++F + +I+ + I+V + Sbjct: 368 PSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTK 427 Query: 258 WKLDTLC-DLYETLTIT-QAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIM 315 ++D L ++ E + + ++ T++ + LT+ + V+ +H ++ ER I+ Sbjct: 428 GQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEII 487 Query: 316 REFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPT-----NRENYIHRIGRGGRFGRKG 370 R+ R G VL+ +LL G+D+ +VSLV D + + I IGR R G Sbjct: 488 RDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAN-G 546 Query: 371 VAINMVTE---------EDKRTLRDIETFYNTSIEEMPLNV 402 I ++ + R I+ YN +P V Sbjct: 547 HVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTV 587 Score = 31.5 bits (70), Expect = 0.63, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 21/58 (36%), Gaps = 6/58 (10%) Query: 78 SGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACI 135 +GTGKT T + + + LV+A + LA Q+ + + Sbjct: 41 TGTGKTFT-----ISNVIAQVNKP-TLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSY 92 >4A2W-A nrPDB Length = 936 Score = 92.7 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 23/193 (11%) Query: 221 LEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFIN 280 +T KF ++ ++ T E + + L D Y T+ ++F Sbjct: 588 QHLTAKFQEKEPELIALSKDETNENPKLEELVC--------ILDDAYRYNPQTRTLLFAK 639 Query: 281 TRRKVDWLTEKMHARDF------TVSAMHGDMDQK------ERDVIMREFR-SGSSRVLI 327 TR V L + M V G DQ + ++ F+ S +R+LI Sbjct: 640 TRALVSALKKCMEENPILNYIKPGVLMGRGRRDQTTGMTLPSQKGVLDAFKTSKDNRLLI 699 Query: 328 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTE--EDKRTLR 385 T + GID+ Q +LV+ Y+ N I GRG G K + + TE E+++ R Sbjct: 700 ATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSKCILVTSKTEVVENEKCNR 759 Query: 386 DIETFYNTSIEEM 398 E N ++E++ Sbjct: 760 YKEEMMNKAVEKI 772 Score = 60.8 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 71/385 (18%), Positives = 134/385 (34%), Gaps = 57/385 (14%) Query: 9 SRDNGPDGMEPEGVIESNWNEIVDSFDDM-----NLSESLLRGIYAYGFEKPSAI----- 58 DN D + E ++ + NLSE+L G A G KP + Sbjct: 191 REDNAKDVDSEMTDASEDCLEASMTYSEEAEPDDNLSENL--GSAAEGIGKPPPVYETKK 248 Query: 59 ----QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ---QIELDLKATQALVLA---P 108 Q P I G + + A +G+GKT +I I + Q + + + LA P Sbjct: 249 ARSYQIELAQPAINGKNALICAPTGSGKTFV-SILICEHHFQNMPAGRKAKVVFLATKVP 307 Query: 109 TRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR 168 E Q + V + G S G V+K+ +E IIV TP + + Sbjct: 308 VYE---QQKNVFKHHFERQGYSVQGISGENFSNVSVEKV-IEDSDIIVVTPQILVNSFED 363 Query: 169 RYL-SPKYIKMFVLDEAD--------EMLSRGFKDQIYDIFQKLNSNTQVVLLSATM--- 216 L S + + DE +L + +Q ++ +L Q++ L+A++ Sbjct: 364 GTLTSLSIFTLMIFDECHNTTGNHPYNVLMTRYLEQKFNSASQLP---QILGLTASVGVG 420 Query: 217 -PSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQA 275 ++ E + + ++ E I++ + + E + + A Sbjct: 421 NAKNIEETIEHICSLCSYLDIQAISTVRENIQELQRFMNKPEIDVRLVKR--RIHNPFAA 478 Query: 276 VI---------FINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREF--RSGSSR 324 +I + T VD L++ +DF + +R + + + SR Sbjct: 479 IISNLMSETEALMRTIAYVDTLSQN-SKKDFGTQNYEHWIVVTQRKCRLLQLEDKEEESR 537 Query: 325 VLITTDLLARGIDVQQVSLVINYDL 349 + + + +L+I+ D Sbjct: 538 ICRALFICTEHLRKYNDALIISEDA 562 >4A2Q-A nrPDB Length = 797 Score = 92.3 bits (228), Expect = 4e-19, Method: Composition-based stats. Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 23/193 (11%) Query: 221 LEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFIN 280 +T KF ++ ++ T E + + L D Y T+ ++F Sbjct: 588 QHLTAKFQEKEPELIALSKDETNENPKLEELVC--------ILDDAYRYNPQTRTLLFAK 639 Query: 281 TRRKVDWLTEKMHARDF------TVSAMHGDMDQK------ERDVIMREFR-SGSSRVLI 327 TR V L + M V G DQ + ++ F+ S +R+LI Sbjct: 640 TRALVSALKKCMEENPILNYIKPGVLMGRGRRDQTTGMTLPSQKGVLDAFKTSKDNRLLI 699 Query: 328 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTE--EDKRTLR 385 T + GID+ Q +LV+ Y+ N I GRG G K + + TE E+++ R Sbjct: 700 ATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSKCILVTSKTEVVENEKCNR 759 Query: 386 DIETFYNTSIEEM 398 E N ++E++ Sbjct: 760 YKEEMMNKAVEKI 772 Score = 60.0 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 71/385 (18%), Positives = 134/385 (34%), Gaps = 57/385 (14%) Query: 9 SRDNGPDGMEPEGVIESNWNEIVDSFDDM-----NLSESLLRGIYAYGFEKPSAI----- 58 DN D + E ++ + NLSE+L G A G KP + Sbjct: 191 REDNAKDVDSEMTDASEDCLEASMTYSEEAEPDDNLSENL--GSAAEGIGKPPPVYETKK 248 Query: 59 ----QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ---QIELDLKATQALVLA---P 108 Q P I G + + A +G+GKT +I I + Q + + + LA P Sbjct: 249 ARSYQIELAQPAINGKNALICAPTGSGKTFV-SILICEHHFQNMPAGRKAKVVFLATKVP 307 Query: 109 TRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR 168 E Q + V + G S G V+K+ +E IIV TP + + Sbjct: 308 VYE---QQKNVFKHHFERQGYSVQGISGENFSNVSVEKV-IEDSDIIVVTPQILVNSFED 363 Query: 169 RYL-SPKYIKMFVLDEAD--------EMLSRGFKDQIYDIFQKLNSNTQVVLLSATM--- 216 L S + + DE +L + +Q ++ +L Q++ L+A++ Sbjct: 364 GTLTSLSIFTLMIFDECHNTTGNHPYNVLMTRYLEQKFNSASQLP---QILGLTASVGVG 420 Query: 217 -PSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQA 275 ++ E + + ++ E I++ + + E + + A Sbjct: 421 NAKNIEETIEHICSLCSYLDIQAISTVRENIQELQRFMNKPEIDVRLVKR--RIHNPFAA 478 Query: 276 VI---------FINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREF--RSGSSR 324 +I + T VD L++ +DF + +R + + + SR Sbjct: 479 IISNLMSETEALMRTIYSVDTLSQN-SKKDFGTQNYEHWIVVTQRKCRLLQLEDKEEESR 537 Query: 325 VLITTDLLARGIDVQQVSLVINYDL 349 + + + +L+I+ D Sbjct: 538 ICRALFICTEHLRKYNDALIISEDA 562 >4A36-A nrPDB Length = 556 Score = 91.6 bits (226), Expect = 6e-19, Method: Composition-based stats. Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 23/193 (11%) Query: 221 LEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFIN 280 +T KF ++ ++ T E + + L D Y T+ ++F Sbjct: 347 QHLTAKFQEKEPELIALSKDETNENPKLEELVC--------ILDDAYRYNPQTRTLLFAK 398 Query: 281 TRRKVDWLTEKMHARDF------TVSAMHGDMDQK------ERDVIMREFR-SGSSRVLI 327 TR V L + M V G DQ + ++ F+ S +R+LI Sbjct: 399 TRALVSALKKCMEENPILNYIKPGVLMGRGRRDQTTGMTLPSQKGVLDAFKTSKDNRLLI 458 Query: 328 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTE--EDKRTLR 385 T + GID+ Q +LV+ Y+ N I GRG G K + + TE E+++ R Sbjct: 459 ATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSKCILVTSKTEVVENEKCNR 518 Query: 386 DIETFYNTSIEEM 398 E N ++E++ Sbjct: 519 YKEEMMNKAVEKI 531 Score = 54.6 bits (130), Expect = 7e-08, Method: Composition-based stats. Identities = 57/328 (17%), Positives = 118/328 (35%), Gaps = 35/328 (10%) Query: 49 AYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ---QIELDLKATQALV 105 A +K + Q P I G + + A +G+GKT +I I + Q + + + Sbjct: 2 AMETKKARSYQIELAQPAINGKNALICAPTGSGKTFV-SILICEHHFQNMPAGRKAKVVF 60 Query: 106 LAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDM 165 LA + +Q + V + G S G V+K+ +E IIV TP + + Sbjct: 61 LATKVPVYEQQKNVFKHHFERQGYSVQGISGENFSNVSVEKV-IEDSDIIVVTPQILVNS 119 Query: 166 LNRRYL-SPKYIKMFVLDEAD--------EMLSRGFKDQIYDIFQKLNSNTQVVLLSATM 216 L S + + DE +L + +Q ++ +L Q++ L+A++ Sbjct: 120 FEDGTLTSLSIFTLMIFDECHNTTGNHPYNVLMTRYLEQKFNSASQLP---QILGLTASV 176 Query: 217 ----PSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTI 272 ++ E + + ++ E I++ + + E + + Sbjct: 177 GVGNAKNIEETIEHICSLCSYLDIQAISTVRENIQELQRFMNKPEIDVRLVKR--RIHNP 234 Query: 273 TQAVI---------FINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREF--RSG 321 A+I + T VD L++ +DF + +R + + + Sbjct: 235 FAAIISNLMSETEALMRTIYSVDTLSQN-SKKDFGTQNYEHWIVVTQRKCRLLQLEDKEE 293 Query: 322 SSRVLITTDLLARGIDVQQVSLVINYDL 349 SR+ + + +L+I+ D Sbjct: 294 ESRICRALFICTEHLRKYNDALIISEDA 321 >2NMV-A nrPDB Length = 661 Score = 88.9 bits (219), Expect = 3e-18, Method: Composition-based stats. Identities = 56/282 (19%), Positives = 102/282 (36%), Gaps = 51/282 (18%) Query: 158 TPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV------L 211 TP + D + M V+DE+ + Q+ +F + QV+ L Sbjct: 321 TPYTLLDYFPDDF-------MIVVDESHVTI-----PQVRGMFNGDQARKQVLVDHGFRL 368 Query: 212 LSA--TMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLY-- 267 SA P E +K M + + + +E + + R LD L D+ Sbjct: 369 PSALDNRPLRFEEF-EKHMHNIVYVSATPGPYEIEHTDEMVEQIIRPTGLLDPLIDVRPI 427 Query: 268 -------------ETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVI 314 + ++ T++ + LT+ + V+ +H ++ ER I Sbjct: 428 EGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIKTLERIEI 487 Query: 315 MREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPT-----NRENYIHRIGRGGRFGRK 369 +R+ R G VL+ +LL G+D+ +VSLV D + + I IGR R + Sbjct: 488 IRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNA-E 546 Query: 370 GVAINMVTE---------EDKRTLRDIETFYNTSIEEMPLNV 402 G I + + + R+ + +N P + Sbjct: 547 GRVIMYADKITKSMEIAINETKRRREQQERFNEEHGITPKTI 588 Score = 28.4 bits (62), Expect = 5.6, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 20/58 (34%), Gaps = 6/58 (10%) Query: 78 SGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACI 135 +GTGKT T + + ++ LV+A + LA Q+ Sbjct: 41 TGTGKTFT-----VSNLIKEVNKP-TLVIAHNKTLAGQLYSEFKEFFPNNAVEYFVSY 92 >6C90-A nrPDB Length = 734 Score = 88.9 bits (219), Expect = 4e-18, Method: Composition-based stats. Identities = 64/437 (14%), Positives = 125/437 (28%), Gaps = 111/437 (25%) Query: 37 MNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIEL 96 + L + + Y F A Q+ AI V+ A + GKT +I + Sbjct: 56 LPLKPRVGKAAKEYPF-ILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALRE 114 Query: 97 DLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIV 156 + + +P + L+ Q + + +G +V Sbjct: 115 KQR---VIFTSPIKALSNQKYREMYEEFQDVGLMTGDVT------------INPTASCLV 159 Query: 157 GTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATM 216 T + ML R + + + DE M + L N V LSAT+ Sbjct: 160 MTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATI 219 Query: 217 PSDVLEVTK---------------KFMRDPIRILVKKEEL-------------------T 242 P+ + + + P++ + T Sbjct: 220 PNA-RQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNT 278 Query: 243 LEGIRQFYINVEREEWK-----------LDTLCDLYETLTITQAVIFINTRRKVDWLTEK 291 + + ++ + + K + + + +IF +++ + + Sbjct: 279 AMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQ 338 Query: 292 MHARDFT---------------------------------------VSAMHGDMDQKERD 312 M DF + HG + ++ Sbjct: 339 MTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKE 398 Query: 313 VIMREFRSGSSRVLITTDLLARGIDVQQVSLVI----NYDLPT----NRENYIHRIGRGG 364 I F G + L T+ A GI++ +++ +D + YI GR G Sbjct: 399 TIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAG 458 Query: 365 RFG--RKGVAINMVTEE 379 R G +G+ I MV E+ Sbjct: 459 RRGMDDRGIVILMVDEK 475 >5JBJ-A nrPDB Length = 680 Score = 84.6 bits (208), Expect = 6e-17, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 50/126 (39%), Gaps = 18/126 (14%) Query: 256 EEWKLDTLCDLYETLTIT----QAVIFINTRRKVDWLTEKMHA------RDFTVSAMHG- 304 E +L L ++ + + ++F TR+ L + + + + G Sbjct: 351 ENPRLSKLEEILQEHFQPPGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGS 410 Query: 305 -------DMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYI 357 M Q E+ ++ FR G +L +T + G+D+ + ++V+ Y L TN + Sbjct: 411 GHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMV 470 Query: 358 HRIGRG 363 GR Sbjct: 471 QAQGRA 476 Score = 58.8 bits (141), Expect = 4e-09, Method: Composition-based stats. Identities = 35/239 (14%), Positives = 72/239 (30%), Gaps = 37/239 (15%) Query: 59 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQ-IQ 117 Q A+ P ++G + I +G GKT A+ + ++ + + VL L QQ ++ Sbjct: 13 QLEAVAPALRGRNSIVWLPTGAGKTRA-AVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLE 71 Query: 118 KVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTP----GRVFDMLNRRYLSP 173 K L D + + G + + +++ T + + Sbjct: 72 KEFHVLRDAFKVTAVS---GDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVEL 128 Query: 174 KYIKMFVLDEADE----------MLSRGFKDQIYDIFQKLNSNTQVVLLSA--------T 215 + V+DE MLS + Q++ L+A + Sbjct: 129 TDFSLLVIDECHHTQKEAVYNKIMLSY-----LQKKLSGQRDLPQILGLTASPGTGGETS 183 Query: 216 MPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQ 274 V + + ++ +E ++ + LC E Q Sbjct: 184 FEGAVEHILQICANLDTEVIASAQEHAQHLQSHVPQPTKQYD-----LCQEREQDPFGQ 237 >3TBK-A nrPDB Length = 555 Score = 84.6 bits (208), Expect = 8e-17, Method: Composition-based stats. Identities = 41/200 (20%), Positives = 72/200 (36%), Gaps = 23/200 (11%) Query: 214 ATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTIT 273 A E+T++F + + + E + L + Y T Sbjct: 339 AAFDETERELTRRFEEKLEELEKVSRDPSNENPK--------LRDLYLVLQEEYHLKPET 390 Query: 274 QAVIFINTRRKVDWLTEKMHARD----FTVSAMHG--------DMDQKERDVIMREFR-S 320 + ++F+ TR VD L + + + G M + ++ FR S Sbjct: 391 KTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGRTNRATGMTLPAQKCVLEAFRAS 450 Query: 321 GSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG-GRFGRKGVAINMVTE- 378 G + +LI T + GID+ + +LVI Y+ N I GRG R + + + Sbjct: 451 GDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGRGRARDSKCFLLTSSADVI 510 Query: 379 EDKRTLRDIETFYNTSIEEM 398 E ++ E N SI + Sbjct: 511 EKEKANMIKEKIMNESILRL 530 Score = 70.0 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 43/253 (16%), Positives = 95/253 (37%), Gaps = 13/253 (5%) Query: 54 KPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIE--LDLKATQALVLAPTRE 111 KP Q LP KG + I A +G GKT + ++ + + + A Sbjct: 4 KPRNYQLELALPAKKGKNTIICAPTGCGKTFVSLLICEHHLKKFPCGQKGKVVFFANQIP 63 Query: 112 LAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYL 171 + +Q V + +G + + G T+ VQ + + II+ TP + + LN + Sbjct: 64 VYEQQATVFSRYFERLGYNIASISGATSDSVSVQHIIEDN-DIIILTPQILVNNLNNGAI 122 Query: 172 -SPKYIKMFVLDEADEML------SRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVT 224 S + + DE F+ + + + + QVV L+A++ + Sbjct: 123 PSLSVFTLMIFDECHNTSKNHPYNQIMFRYLDHKLGESRDPLPQVVGLTASVGVGDAKTA 182 Query: 225 KKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTIT--QAVIFINTR 282 ++ M+ ++ + + +R +E+ +K + + T + +I Sbjct: 183 EEAMQHICKLCAALDASVIATVRDNVAELEQVVYKPQKISRKVASRTSNTFKCII-SQLM 241 Query: 283 RKVDWLTEKMHAR 295 ++ + L + + Sbjct: 242 KETEKLAKDVSEE 254 >3P4X-A nrPDB Length = 413 Score = 83.5 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 66/332 (19%), Positives = 115/332 (34%), Gaps = 49/332 (14%) Query: 66 CIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGD 125 ++G A +G GKT TF ++ + L K ++ ++ PT L +Q + + L D Sbjct: 32 IVQGKSFTMVAPTGVGKT-TFG--MMTALWLARKGKKSALVFPTVTLVKQTLERLQKLAD 88 Query: 126 YMGASCHACIGGTNVRAEVQKLQMEAP---HIIV-----GTPGRVFDMLNRRYLSPKYIK 177 + + + HI+V + R R Sbjct: 89 E-KVKIFGFYSSMKKEEKEKFEKSFEEDDYHILVFSTQFVSKNREKLSQKRFDFVFVDDV 147 Query: 178 MFVLDEA---DEMLSR-GFKDQIYD----------IFQKLNSNTQVVLL--SATM-PSDV 220 VL + D +L G ++I I+++ + +L+ SAT P + Sbjct: 148 DAVLKASRNIDTLLMMVGIPEEIIRKAFSTIKQGKIYERPKNLKPGILVVSSATAKPRGI 207 Query: 221 LEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFIN 280 + RD + V + I I+ +E L +L E + +IF Sbjct: 208 RPLL---FRDLLNFTVGRLVSVARNITHVRISSRSKEK----LVELLE-IFRDGILIFAQ 259 Query: 281 TRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDL----LARGI 336 T + L E + F V E + +F+ G +LI L RG+ Sbjct: 260 TEEEGKELYEYLKRFKFNVGE-----TWSEFEKNFEDFKVGKINILIGVQAYYGKLTRGV 314 Query: 337 DVQQ-VSLVINYDLP--TNRENYIHRIGRGGR 365 D+ + + VI + P + YI GR R Sbjct: 315 DLPERIKYVIFWGTPSGPDVYTYIQASGRSSR 346 >2FWR-A nrPDB Length = 472 Score = 82.7 bits (203), Expect = 3e-16, Method: Composition-based stats. Identities = 26/114 (22%), Positives = 53/114 (46%), Gaps = 5/114 (4%) Query: 255 REEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVI 314 + K+ L ++ E + +IF V +++ F + A+ ++ER+ I Sbjct: 332 NSKNKIRKLREILERHRKDKIIIFTRHNELVYRISKV-----FLIPAITHRTSREEREEI 386 Query: 315 MREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR 368 + FR+G R ++++ +L GIDV ++ + + YI R+GR R + Sbjct: 387 LEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREYIQRLGRILRPSK 440 >4ON9-A nrPDB Length = 580 Score = 81.6 bits (200), Expect = 6e-16, Method: Composition-based stats. Identities = 44/201 (21%), Positives = 72/201 (35%), Gaps = 23/201 (11%) Query: 213 SATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTI 272 +A ++T++F + + + E + E L + Y Sbjct: 363 AAGFDEIEQDLTQRFEEKLQELESVSRDPSNENPK--------LEDLCFILQEEYHLNPE 414 Query: 273 TQAVIFINTRRKVDWLTE------KMHARDFTVSAMHGDMDQK------ERDVIMREFR- 319 T ++F+ TR VD L K+ + G +Q + I+ F+ Sbjct: 415 TITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPAQKCILDAFKA 474 Query: 320 SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTE- 378 SG +LI T + GID+ Q +LVI Y+ N I GRG G K + Sbjct: 475 SGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLTSNAGV 534 Query: 379 -EDKRTLRDIETFYNTSIEEM 398 E ++ E N SI + Sbjct: 535 IEKEQINMYKEKMMNDSILRL 555 Score = 76.9 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 42/252 (16%), Positives = 90/252 (35%), Gaps = 15/252 (5%) Query: 53 EKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIE--LDLKATQALVLAPTR 110 KP Q LP +KG + I A +G GKT + ++ + + + A Sbjct: 28 FKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQI 87 Query: 111 ELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRY 170 + +Q + V + G G T V+++ II+ TP + + L + Sbjct: 88 PVYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENN-DIIILTPQILVNNLKKGT 146 Query: 171 L-SPKYIKMFVLDEAD--------EMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVL 221 + S + + DE M+ + DQ + QV+ L+A++ Sbjct: 147 IPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQ--KLGGSSGPLPQVIGLTASVGVGDA 204 Query: 222 EVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYE-TLTITQAVIFIN 280 + T + + ++ + + ++ +E+ +K E ++ I Sbjct: 205 KNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQ 264 Query: 281 TRRKVDWLTEKM 292 R + L +++ Sbjct: 265 LMRDTESLAKRI 276 >4BPB-A nrPDB Length = 698 Score = 81.6 bits (200), Expect = 7e-16, Method: Composition-based stats. Identities = 44/203 (21%), Positives = 72/203 (35%), Gaps = 25/203 (12%) Query: 213 SATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTI 272 +A ++T++F + + + E + E L + Y Sbjct: 347 AAGFDEIEQDLTQRFEEKLQELESVSRDPSNENPK--------LEDLCFILQEEYHLNPE 398 Query: 273 TQAVIFINTRRKVDWLTE------KMHARDFTVSAMHGDMDQK--------ERDVIMREF 318 T ++F+ TR VD L K+ + G +Q + I+ F Sbjct: 399 TITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTFFGMTLPAQKCILDAF 458 Query: 319 R-SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVT 377 + SG +LI T + GID+ Q +LVI Y+ N I GRG G K + Sbjct: 459 KASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLTSNA 518 Query: 378 E--EDKRTLRDIETFYNTSIEEM 398 E ++ E N SI + Sbjct: 519 GVIEKEQINMYKEKMMNDSILRL 541 Score = 77.3 bits (189), Expect = 1e-14, Method: Composition-based stats. Identities = 42/252 (16%), Positives = 90/252 (35%), Gaps = 15/252 (5%) Query: 53 EKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIE--LDLKATQALVLAPTR 110 KP Q LP +KG + I A +G GKT + ++ + + + A Sbjct: 12 FKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQI 71 Query: 111 ELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRY 170 + +Q + V + G G T V+++ II+ TP + + L + Sbjct: 72 PVYEQNKSVFSKYFERHGYRVTGISGATAENVPVEQIVENN-DIIILTPQILVNNLKKGT 130 Query: 171 L-SPKYIKMFVLDEAD--------EMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVL 221 + S + + DE M+ + DQ + QV+ L+A++ Sbjct: 131 IPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQ--KLGGSSGPLPQVIGLTASVGVGDA 188 Query: 222 EVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYE-TLTITQAVIFIN 280 + T + + ++ + + ++ +E+ +K E ++ I Sbjct: 189 KTTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQ 248 Query: 281 TRRKVDWLTEKM 292 R + L +++ Sbjct: 249 LMRDTESLAKRI 260 >1C4O-A nrPDB Length = 664 Score = 81.2 bits (199), Expect = 8e-16, Method: Composition-based stats. Identities = 44/205 (21%), Positives = 80/205 (39%), Gaps = 24/205 (11%) Query: 192 FKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYI 251 F++ + + +QVV +SAT L + + + IR G+ + Sbjct: 373 FEEFLERV-------SQVVFVSATPGPFELAHSGRVVEQIIRPT---------GLLDPLV 416 Query: 252 NVEREEWKLDTLCDLYETL--TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQK 309 V+ E ++ L + + ++ + T R + LT + +H ++D Sbjct: 417 RVKPTENQILDLMEGIRERAARGERTLVTVLTVRMAEELTSFLVEHGIRARYLHHELDAF 476 Query: 310 ERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPT-----NRENYIHRIGRGG 364 +R ++R+ R G L+ +LL G+D+ +VSLV D + + I IGR Sbjct: 477 KRQALIRDLRLGHYDCLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAA 536 Query: 365 RFGRKGVAINMVTEEDKRTLRDIET 389 R R G + R IE Sbjct: 537 RNAR-GEVWLYADRVSEAMQRAIEE 560 Score = 32.6 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 13/84 (15%) Query: 49 AYGFEKPSAI--QQRAILPCIKG-YD----VIAQAQSGTGKTATFAISILQQIELDLKAT 101 + + PS Q +AI ++ D V +GTGKT T + ++ L Sbjct: 1 TFRYRGPSPKGDQPKAIAGLVEALRDGERFVTLLGATGTGKTVT-----MAKVIEALGRP 55 Query: 102 QALVLAPTRELAQQIQKVVMALGD 125 ALVLAP + LA Q+ L Sbjct: 56 -ALVLAPNKILAAQLAAEFRELFP 78 >6DCR-A nrPDB Length = 694 Score = 78.5 bits (192), Expect = 5e-15, Method: Composition-based stats. Identities = 77/471 (16%), Positives = 146/471 (30%), Gaps = 117/471 (24%) Query: 10 RDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKG 69 R P P+ + S E F D + ++ E Q A+ Sbjct: 125 RQGRPAANAPDIDLASETPE----FSDWRTNYAVSGERLRLNTE-----QATAVGAIHSA 175 Query: 70 YDV----IAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGD 125 D + +G+GKT + +S+L+ + + QALV+ P L Q + + Sbjct: 176 ADTFSAWLLAGVTGSGKTEVY-LSVLENVLA--QGKQALVMVPEIGLTPQT---IARFRE 229 Query: 126 YMGASCHACIGGTNVRAEVQ---KLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLD 182 A G N + K + I++GT +F K + + V+D Sbjct: 230 RFNAPVEVLHSGLNDSERLSAWLKAKNGEAAIVIGTRSALF-------TPFKNLGVIVID 282 Query: 183 EADEML---SRGFKDQIYDIFQKLNSNTQ--VVLLSATMPSDVLEVTKKFMRDPIRILVK 237 E + G++ D+ + Q ++L SAT + + + + + Sbjct: 283 EEHDSSYKQQEGWRYHARDLAVYRAHSEQIPIILGSAT--PALETLCNVQQKKYRLLRLT 340 Query: 238 KEELTLEGIRQFYINVEREEWKLDTLCDLYET-----LTITQAVIFINTR--------RK 284 + Q ++++ ++ + L Q ++F+N R Sbjct: 341 RRAGNARPAIQHVLDLKGQKVQAGLAPALITRMRQHLQADNQVILFLNRRGFAPALLCHD 400 Query: 285 VDWLTEK--------MHARDFTVSAMHGD-----------------------MDQKER-- 311 W+ E +H + H D +Q E+ Sbjct: 401 CGWIAECPRCDHYYTLHQAQHHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTL 460 Query: 312 -----------------------DVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYD 348 + + E G +R+LI T +LA+G V+LV D Sbjct: 461 APLFPGVPISRIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLD 520 Query: 349 L------------PTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387 + + Y GR GR G++G + + L+ + Sbjct: 521 VDGALFSADFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTL 571 >4XGT-A nrPDB Length = 993 Score = 75.0 bits (183), Expect = 6e-14, Method: Composition-based stats. Identities = 63/430 (14%), Positives = 124/430 (28%), Gaps = 123/430 (28%) Query: 57 AIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQI 116 Q ++ + V+ A + GKT +I Q ++ K + + +P + L+ Q Sbjct: 70 PFQALSVASIEREESVLVSAHTSAGKTVVAEYAIAQCLK---KNQRVIYTSPIKALSNQK 126 Query: 117 QKVVMA-LGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKY 175 + A GD G + L V T + ML R + Sbjct: 127 YRDFQAEFGD-----VGLMTGDVTINPTASCL--------VMTTEILRSMLYRGSEIMRE 173 Query: 176 IKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMP------SDVLEVTKKF-- 227 + V DE M + + L + V LSAT+P + ++ ++ Sbjct: 174 VAWVVFDEIHYMRDKIRGVVWEETIILLPDKVRYVFLSATIPNAFQFAEWIAKIHRQACH 233 Query: 228 ----------MRDPIR------ILVKKEELTL---EGIRQFYINVER------------- 255 +++ IL+ +E Q +E Sbjct: 234 VVYTDFRPTPLQNYFFPAGGKGILLIVDEKGNFKENNFNQAMAMIEEKKGTDSNDWSAKQ 293 Query: 256 -----------------EEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFT 298 E+ + + + ++F ++R+ + + + F Sbjct: 294 KGKGKNKKTNKGGEAADEKADIAKIIKMILKKNFQPVIVFNFSKRECEQMALASSSMKFN 353 Query: 299 V---------------------------------------SAMHGDMDQKERDVIMREFR 319 H + ++ I F+ Sbjct: 354 APDEENMVNKVFENALASLSEDDKNLPQISNILPLLRKGIGVHHSGLLPILKETIEILFQ 413 Query: 320 SGSSRVLITTDLLARGIDVQQVSLVI--------NYDLPTNRENYIHRIGRGGRFGR--K 369 G +VL T+ + G+++ ++V P YI GR GR G + Sbjct: 414 EGLIKVLFATETFSIGLNMPARTVVFTQVTKWDGQQRRPLTSSEYIQMAGRAGRRGLDDR 473 Query: 370 GVAINMVTEE 379 G+ I MV ++ Sbjct: 474 GIVIMMVDDK 483 >6HEG-A nrPDB Length = 809 Score = 71.5 bits (174), Expect = 7e-13, Method: Composition-based stats. Identities = 58/354 (16%), Positives = 136/354 (38%), Gaps = 47/354 (13%) Query: 60 QRAILPCIKGYDV----IAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQ 115 + + D + A +G GK+ LQ + + ++L P R LA Sbjct: 7 AAVLPELLTALDCAPQVLLSAPTGAGKS---TWLPLQLLAHPGINGKIILLEP-RRLAA- 61 Query: 116 IQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKY 175 + V L + + +G R Q + V T G + M+ R Sbjct: 62 -RNVAQRLAELLNEKPGDTVG---YRMRAQNCVGPNTRLEVVTEGVLTRMIQRDP-ELSG 116 Query: 176 IKMFVLDEADE--MLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIR 233 + + +LDE E + + + D+ Q L + +++++SAT+ +D L+ P Sbjct: 117 VGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLDNDRLQQML-----PEA 171 Query: 234 ILVKKEELTLEGIRQFYINV---EREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTE 290 +V E + + + Y+ + +R + + ++F+ ++ + E Sbjct: 172 PVVISEGRSFP-VERRYLPLPAHQRFDDAVAVATAEMLRQESGSLLLFLPGVGEIQRVQE 230 Query: 291 KMHAR---DFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVI-- 345 ++ +R D + ++G + ++ + G +V++ T++ + ++ + LV+ Sbjct: 231 QLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAETSLTIEGIRLVVDC 290 Query: 346 ------NYDLPT----------NRENYIHRIGRGGRFGRKGVAINMVTEEDKRT 383 +D T ++ + R GR GR G++++++ +E Sbjct: 291 AQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRL-EPGISLHLIAKEQAER 343 >4NL8-A nrPDB Length = 747 Score = 70.8 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 68/399 (17%), Positives = 128/399 (32%), Gaps = 104/399 (26%) Query: 78 SGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGG 137 +G+GKT + +S+L+ + + QALV+ P L Q + A G Sbjct: 241 TGSGKTEVY-LSVLENVLA--QGRQALVMVPEIGLTPQT---IARFRQRFNAPVEVLHSG 294 Query: 138 TNVRAEVQ---KLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEML---SRG 191 N + K + I++GT +F K + + V+DE + G Sbjct: 295 LNDSERLSAWLKAKNGEAAIVIGTRSSLF-------TPFKDLGVIVIDEEHDSSYKQQEG 347 Query: 192 FKDQIYDIFQKLNSNTQ--VVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQF 249 ++ D+ + Q ++L SAT + L ++ ++ + K +Q Sbjct: 348 WRYHARDLAVWRAHSEQIPIILGSATPALETLHNVRQ--GKYRQLTLSKRAGNARPAQQH 405 Query: 250 YINVEREEWKLDTLCDLYET-----LTITQAVIFINTR--------RKVDWLTEK----- 291 ++++ + + L Q ++F+N R W+ E Sbjct: 406 VLDLKGQPLQAGLSPALISRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDS 465 Query: 292 ---MHARDFTVSAMHGD-----------------------MDQKER-------------- 311 +H + H D +Q E+ Sbjct: 466 YYTLHQAQHHLRCHHCDSQRPIPRQCPSCGSTHLVPVGIGTEQLEQALAPLFPEVPISRI 525 Query: 312 -----------DVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----------- 349 + + G +R+LI T +LA+G V+LV D+ Sbjct: 526 DRDTTSRKGALEEHLAAVHRGGARILIGTQMLAKGHHFPDVTLVSLLDVDGALFSADFRS 585 Query: 350 -PTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387 + Y GR GR G++G I + L+ + Sbjct: 586 AERFAQLYTQVSGRAGRAGKQGEVILQTHHPEHPLLQTL 624 >5VHD-D nrPDB Length = 870 Score = 69.6 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 79/498 (15%), Positives = 154/498 (30%), Gaps = 108/498 (21%) Query: 8 RSRDNGPDGMEPEGVIESNWNEIVDS--FDDMNLSESLLRGIYAYGFEKPSA---IQQRA 62 R RD D + E+ + +D +D+ ++ LR I F + +Q+ Sbjct: 10 RIRDKYIDRDSEYLLQENEPDATLDQQLLEDLQKKKTDLRYIEMQRFREKLPSYGMQKEL 69 Query: 63 ILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLA--PTRELAQQIQKVV 120 + + ++G GKT IL K + ++ P R A + + V Sbjct: 70 VNMIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERV 129 Query: 121 MALGDYMGASCHACIGGTNVRAEVQ---KLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIK 177 A +C G + +++ +L + I+ T G + L + Sbjct: 130 AA------ERAESCGNGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDP-HLSSVS 182 Query: 178 MFVLDEAD-EMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSD----------------- 219 VLDE L + + +VVL+SAT+ ++ Sbjct: 183 HIVLDEIHERNLQSDVLMTVVKDLLSYRPDLKVVLMSATLNAEKFSEYFGNCPMIHIPGF 242 Query: 220 ----VLEVTKKFMRDPIRILVKKE------------------------------ELTLEG 245 V + + + + +KE L Sbjct: 243 TFPVVEYLLEDIIEKIRYVPEQKEHRSQFKKGFMQGHVNRQEKYYYEAIYKERWPGYLRE 302 Query: 246 IRQFY--------INVEREEWKLDTLCDLYE----TLTITQAVIFINTRRKVDWLTEKM- 292 +RQ Y ++ E+ L+ + L ++F+ + L + + Sbjct: 303 LRQRYSASTVDVVEMMDDEKVDLNLIAALIRYIVLEEEDGAILVFLPGWDNISTLHDLLM 362 Query: 293 -----HARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVI-- 345 + F + +H M + + + G +++I T++ I + V VI Sbjct: 363 SQVMFKSDKFIIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDG 422 Query: 346 ------NYDLPTNRENY----------IHRIGRGGRFGRKGVAINMVTEEDKRTLRDIE- 388 ++D N R GR GR + G ++ L D + Sbjct: 423 GKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRV-QPGHCYHLYNSLRASLLDDYQL 481 Query: 389 -TFYNTSIEEMPLNVADL 405 T +EE+ L + L Sbjct: 482 PEILRTPLEELCLQIKIL 499 >4A4Z-A nrPDB Length = 997 Score = 67.7 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 46/266 (17%), Positives = 101/266 (37%), Gaps = 40/266 (15%) Query: 13 GPDGMEPEGVIESNWNEI---VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKG 69 GPD M P ++ ++ +++FD++ + + ++ FE + Q+ A+ +G Sbjct: 1 GPDSMVPVKKEWAHVVDLNHKIENFDELIPNPA-----RSWPFELDT-FQKEAVYHLEQG 54 Query: 70 YDVIAQAQSGTGKT--ATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYM 127 V A + GKT A +AI++ + T+ + +P + L+ Q + D Sbjct: 55 DSVFVAAHTSAGKTVVAEYAIAMAHR-----NMTKTIYTSPIKALSNQKFRDFKETFD-- 107 Query: 128 GASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEM 187 + G + + L + T + ML R + ++ + DE + Sbjct: 108 DVNIGLITGDVQINPDANCL--------IMTTEILRSMLYRGADLIRDVEFVIFDEVHYV 159 Query: 188 LSRGFKDQIYDIFQKLNSNTQVVLLSATMPS--DVLEVTKKFMRD------------PIR 233 + ++ L + + +LLSAT+P+ + + + P+ Sbjct: 160 NDQDRGVVWEEVIIMLPQHVKFILLSATVPNTYEFANWIGRTKQKNIYVISTPKRPVPLE 219 Query: 234 ILVKKEELTLEGIRQFYINVEREEWK 259 I + ++ + I Q +E K Sbjct: 220 INIWAKKELIPVINQNSEFLEANFRK 245 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 26/200 (13%), Positives = 55/200 (27%), Gaps = 51/200 (25%) Query: 245 GIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDF------- 297 R+F+ + + + + V+F+ ++++ + + + +F Sbjct: 309 NKRKFFTQDGPSKKTWPEIVNYLRKRELLPMVVFVFSKKRCEEYADWLEGINFCNNKEKS 368 Query: 298 --------------------------------TVSAMHGDMDQKERDVIMREFRSGSSRV 325 ++ HG + +++I F G +V Sbjct: 369 QIHMFIEKSITRLKKEDRDLPQILKTRSLLERGIAVHHGGLLPIVKELIEILFSKGFIKV 428 Query: 326 LITTDLLARGIDVQQVSLVINYDLPT---------NRENYIHRIGRGGRFG--RKGVAIN 374 L T+ A G+++ VI + + GR GR G G I Sbjct: 429 LFATETFAMGLNLPT-RTVIFSSIRKHDGNGLRELTPGEFTQMAGRAGRRGLDSTGTVIV 487 Query: 375 MVTEEDKRTLRDIETFYNTS 394 M E Sbjct: 488 MAYNSPLSIATFKEVTMGVP 507 >2OCA-A nrPDB Length = 510 Score = 67.3 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 56/371 (15%), Positives = 120/371 (32%), Gaps = 45/371 (12%) Query: 32 DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL 91 FD+ + G +P Q+ A+ + I + G++ ++L Sbjct: 94 KDFDEWLSKLEIYSGNKRI---EPHWYQKDAVFEGLVNRRRILNLPTSAGRSL--IQALL 148 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEA 151 + L+ + L++ PT L Q+ + + A GG + + Sbjct: 149 ARYYLENYEGKILIIVPTTALTTQMADDFVDYRLFSHAMIKKIGGGASKDDKY----KND 204 Query: 152 PHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD----------------EMLSRGFKDQ 195 ++VGT V + M + DE M G Sbjct: 205 APVVVGTWQTVV---KQPKEWFSQFGMMMNDECHLATGKSISSIISGLNNCMFKFGLSGS 261 Query: 196 IYD----IFQKL--------NSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTL 243 + D I Q + T ++ + L++ F+R P K + T Sbjct: 262 LRDGKANIMQYVGMFGEIFKPVTTSKLMEDGQVTE--LKINSIFLRYPDEFTTKLKGKTY 319 Query: 244 EGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMH 303 + + + + + L V+F + + + V + Sbjct: 320 QEEIKIITGLSKRNKWIAKLAIKLAQKDENAFVMF-KHVSHGKAIFDLIKNEYDKVYYVS 378 Query: 304 GDMDQKERDVIMREFRSGSSRVLITT-DLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 362 G++D + R+++ +G +++ + + + GI V+ + V+ ++ + IGR Sbjct: 379 GEVDTETRNIMKTLAENGKGIIIVASYGVFSTGISVKNLHHVVLAHGVKSKIIVLQTIGR 438 Query: 363 GGR-FGRKGVA 372 R G K +A Sbjct: 439 VLRKHGSKTIA 449 >6F4A-B nrPDB Length = 644 Score = 66.9 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 65/395 (16%), Positives = 137/395 (34%), Gaps = 71/395 (17%) Query: 30 IVDSFDDMNLSESLL---------RGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGT 80 ++ S+ D L++ ++ +++ F P+ A I+ + ++ + + Sbjct: 113 LLSSYYDCILNQEIIPSMLNTGTDDSVHSVDFSNPAEWFPEA--RKIRRHIIMHVGPTNS 170 Query: 81 GKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNV 140 GKT LQ+++ + A P R LA+++ + + C+ G Sbjct: 171 GKTFR----SLQKLKAADRGYYA---GPLRLLAREVYEK----FKHENVRCNLLTG---- 215 Query: 141 RAEVQKLQMEA--PHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEM--LSRGFKDQI 196 ++ L ++ GT +M+ + + VLDE M L RG+ Sbjct: 216 EEVIKDLDEMGNEANLTSGT----IEMIPLN----QNFDVVVLDEIQMMADLDRGWA-WT 266 Query: 197 YDIFQKLNSNTQVVLLSATMP--SDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVE 254 + ++T+P ++E+T + + K + VE Sbjct: 267 NALLGAKAKEVHCCGEASTIPLIKKIVEMTGDKLTINEYERMGK------------LVVE 314 Query: 255 REEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVI 314 E L Y +L V+ + + +D E + + ++G + + R Sbjct: 315 EE-----ALTKGYHSLKKGDCVVAFSKKAILDLKLEIEKKTELKAAVIYGSLPPETRVKQ 369 Query: 315 MREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI--------GRGGRF 366 F SG +LI +D + G+++ +V + + + GR GRF Sbjct: 370 ANLFNSGEFDILIASDAIGMGLNLSIDRVVFTTSKKFDGRDMVDMTSSAIKQIGGRAGRF 429 Query: 367 G-----RKGVAINMVTEEDKRTLRDIETFYNTSIE 396 + + +T L+ + N IE Sbjct: 430 KQNIHDNGELPVGYITAVKPNVLKAVREAINAPIE 464 >5WX1-A nrPDB Length = 733 Score = 61.9 bits (149), Expect = 5e-10, Method: Composition-based stats. Identities = 50/313 (15%), Positives = 106/313 (33%), Gaps = 56/313 (17%) Query: 78 SGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGG 137 +G GKT S++++I + + LVL P R A+ + + + + + + IG Sbjct: 278 TGAGKTTELPRSVIEEIG---RHKRVLVLIPLRAAAESVYQYMRQ--KHPSIAFNLRIGE 332 Query: 138 TNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIY 197 + + P + + LDE + Sbjct: 333 MKEGDMATGITYASYGYFCQMP------QPKLRAAMVEYSFIFLDEYHCA-----TPEQL 381 Query: 198 DIFQKLNS---NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVE 254 I K++ N +VV ++AT V +K PI + E + E + Y+++ Sbjct: 382 AIMGKIHRFSENLRVVAMTATPAGTVTTTGQKH---PIEEFIAPEVMKGEDLGSEYLDIA 438 Query: 255 REEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVI 314 + ++ + + ++F+ TR +K+ A+ + + E Sbjct: 439 GLKIPVEEMK--------SNMLVFVPTRNMAVETAKKLKAKGYNSGYYYSG----EDPSN 486 Query: 315 MREFRSGSSRVLITTDLLARGIDVQQVSLVINYD----------------------LPTN 352 +R S S V++ T+ + G+ + + +V++ + Sbjct: 487 LRVVTSQSPYVVVATNAIESGVTLPDLDVVVDTGLKCEKRIRLSSKMPFIVTGLKRMAVT 546 Query: 353 RENYIHRIGRGGR 365 R GR GR Sbjct: 547 IGEQAQRRGRVGR 559 >5WSO-A nrPDB Length = 476 Score = 61.1 bits (147), Expect = 9e-10, Method: Composition-based stats. Identities = 52/312 (16%), Positives = 112/312 (35%), Gaps = 54/312 (17%) Query: 78 SGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGG 137 +G GKT +++++I + + LVL P R A+ + + + + S + IG Sbjct: 21 TGAGKTTELPKAVIEEIG---RHKRVLVLIPLRAAAESVYQYMRL--KHPSISFNLRIGD 75 Query: 138 TNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIY 197 + + P + + LDE +Q+ Sbjct: 76 MKEGDMATGITYASYGYFCQMP------QPKLRAAMVEYSYIFLDEYHCATP----EQLA 125 Query: 198 DIFQ--KLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVER 255 I + + + + +VV ++AT V +K PI + E + E + ++++ Sbjct: 126 IIGKIHRFSESIRVVAMTATPAGSVTTTGQKH---PIEEFIAPEVMKGEDLGSQFLDIAG 182 Query: 256 EEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIM 315 + +D + ++F+ TR + +K+ A+ + + E + Sbjct: 183 LKIPVDEMK--------GNMLVFVPTRNMAVEVAKKLKAKGYNSGYYYSG----EDPANL 230 Query: 316 REFRSGSSRVLITTDLLARGIDVQQVSLVINYDL-------PTNRENYI----------- 357 R S S V++ T+ + G+ + + VI+ L +++ +I Sbjct: 231 RVVTSQSPYVIVATNAIESGVTLPDLDTVIDTGLKCEKRVRVSSKIPFIVTGLKRMAVTV 290 Query: 358 ----HRIGRGGR 365 R GR GR Sbjct: 291 GEQAQRRGRVGR 302 >5N8S-A nrPDB Length = 944 Score = 59.6 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 81/432 (18%), Positives = 142/432 (32%), Gaps = 95/432 (21%) Query: 61 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQI--ELDLKATQALVLAPTRELAQQIQK 118 I + ++ +G GKT +L + + + P R A I + Sbjct: 161 DIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQPRRISAIAIAE 220 Query: 119 -VVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIK 177 V + +G S G +R E +K + I T G + L L + Sbjct: 221 WVSYERCESLGNSV-----GYQIRLESRKARER-ASITYCTTGVLLQQLQSDPL-MHNLS 273 Query: 178 MFVLDEAD-EMLSRGFKDQIYDIFQKLNSNTQVVLLSAT--------------------- 215 + +LDE + + + + +V+L+SAT Sbjct: 274 VLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSATVREQDFCDYFNNCPMFRIEGV 333 Query: 216 -MP------SDVLEVT---------KKFMRDPIRILVKKE---ELTLEGIRQFYIN---- 252 P DVL T ++ RDP +K E E L IR Y + Sbjct: 334 MFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNSYDSRVLD 393 Query: 253 ---------VEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARD------- 296 E ++ D + + E ++F+ K+ L + Sbjct: 394 KLRLPESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPKTSKGQRW 453 Query: 297 ---FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVI-------- 345 V +H M E+ + R +G +V+I+T + + + V VI Sbjct: 454 RDHMAVFPLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKAT 513 Query: 346 NYDLPTNRENY----------IHRIGRGGRFGRKGVAINMVTEEDKRTLRDI--ETFYNT 393 NYD+ TN ++ R GR GR R G+ N+ + + + DI + Sbjct: 514 NYDIETNIQSLDEVWVTKANTQQRRGRAGRV-RPGICYNLFSRAREDRMDDIPTPEILRS 572 Query: 394 SIEEMPLNVADL 405 +E + L++ L Sbjct: 573 KLESIILSLKLL 584 >5D0U-A nrPDB Length = 714 Score = 59.6 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 50/353 (14%), Positives = 115/353 (32%), Gaps = 58/353 (16%) Query: 72 VIAQAQSGTGKTATFAIS--ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGA 129 ++ ++G+GKT I +L P R A V + D + Sbjct: 57 LVFVGETGSGKTT--QIPQYVLYDELPHQTGKLIACTQPRRVAAM---SVAQRVADELDV 111 Query: 130 SCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD-EML 188 +G + + T G++ +LDEA L Sbjct: 112 KLGEEVG---YSIRFENKTSSKTLLKYMTDGQLLREAMHDR-DMSRYSCIILDEAHERTL 167 Query: 189 SRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQ 248 + + + + +++++SAT+ D + F P+ + + + Sbjct: 168 ATDILMALLKQLSERRKDLKIIVMSATL--DAQKFQSYFFNAPLLAVPGR----THPVEI 221 Query: 249 FYINVEREEW---KLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMH-----------A 294 FY ++ + T+ ++ ++F+ +++ ++ A Sbjct: 222 FYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDACRRISLEVDEMIRESDA 281 Query: 295 RDFTVSAMHGDMDQKERDVIMRE----FRSGSS---RVLITTDLLARGIDVQQVSLVI-- 345 +V ++G + ++ I + FR G + ++ T++ + + + V+ Sbjct: 282 GPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVYVVDP 341 Query: 346 ------NYDL----------PTNRENYIHRIGRGGRFGRKGVAINMVTEEDKR 382 Y+ P ++ + R GR GR R G + TEE + Sbjct: 342 GFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGR-TRPGKCFRLYTEEAFK 393 >4CBI-A nrPDB Length = 516 Score = 59.2 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 50/315 (15%), Positives = 108/315 (34%), Gaps = 60/315 (19%) Query: 78 SGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGG 137 +G GKT S++++I + + LVL P R A+ + + + + + + IG Sbjct: 53 TGAGKTTELPRSVIEEIG---RHKRVLVLIPLRAAAESVYQYMRQ--KHPSIAFNLRIGE 107 Query: 138 TNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKM--FVLDEADEMLSRGFKDQ 195 + + +++ L ++ LDE + Sbjct: 108 MKEGDMATGITYASYGYFC--------QMSQPKLRAAMVEYSFIFLDEYHCA-----TPE 154 Query: 196 IYDIFQKLNS---NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYIN 252 I K++ N +VV ++AT V +K PI + E + E + Y++ Sbjct: 155 QLAIMGKIHRFSENLRVVAMTATPAGTVTTTGQKH---PIEEFIAPEVMKGEDLGSEYLD 211 Query: 253 VEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERD 312 + + ++ + ++F+ TR +K+ A+ + + E Sbjct: 212 IAGLKIPVEEMK--------NNMLVFVPTRNMAVEAAKKLKAKGYNSGYYYSG----EDP 259 Query: 313 VIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYD----------------------LP 350 +R S S V++ T+ + G+ + + +V++ + Sbjct: 260 SNLRVVTSQSPYVVVATNAIESGVTLPDLDVVVDTGLKCEKRIRLSPKMPFIVTGLKRMA 319 Query: 351 TNRENYIHRIGRGGR 365 R GR GR Sbjct: 320 VTIGEQAQRRGRVGR 334 >5I8Q-A nrPDB Length = 767 Score = 58.8 bits (141), Expect = 4e-09, Method: Composition-based stats. Identities = 62/407 (15%), Positives = 136/407 (33%), Gaps = 66/407 (16%) Query: 18 EPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIA-QA 76 + + ++ F + + I E P Q+ L + ++ Sbjct: 58 TSAEEAQKLEDGKINPFTGREFTPKYVD-ILKIRRELPVHAQRDEFLKLYQNNQIMVFVG 116 Query: 77 QSGTGKTATFAIS--ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHAC 134 ++G+GKT I +L L+ TQ P R A V + + M Sbjct: 117 ETGSGKTT--QIPQFVLFDEMPHLENTQVACTQPRRVAAM---SVAQRVAEEMDVKLGEE 171 Query: 135 IGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEM-----LS 189 +G + + T G + + +LDEA E + Sbjct: 172 VG---YSIRFENKTSNKTILKYMTDGMLLREAMEDH-DLSRYSCIILDEAHERTLATDIL 227 Query: 190 RGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQF 249 G Q+ + +++++SAT+ D + + F P+ + + + + Sbjct: 228 MGLLKQVVK----RRPDLKIIIMSATL--DAEKFQRYFNDAPLLAVPGRTYP----VELY 277 Query: 250 YINVEREEW---KLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARD---------- 296 Y + ++ + T+ ++ T ++F+ +++ K+ Sbjct: 278 YTPEFQRDYLDSAIRTVLQIHATEEAGDILLFLTGEDEIEDAVRKISLEGDQLVREEGCG 337 Query: 297 -FTVSAMHGDMDQKERDVIMR---EFRSGS--SRVLITTDLLARGIDVQQVSLVI----- 345 +V ++G + ++ I E +G +V+I+T++ + + + V+ Sbjct: 338 PLSVYPLYGSLPPHQQQRIFEPAPESHNGRPGRKVVISTNIAETSLTIDGIVYVVDPGFS 397 Query: 346 ---NYDL----------PTNRENYIHRIGRGGRFGRKGVAINMVTEE 379 Y+ P ++ + R GR GR R G + TEE Sbjct: 398 KQKVYNPRIRVESLLVSPISKASAQQRAGRAGR-TRPGKCFRLYTEE 443 >5GM6-Y nrPDB Length = 876 Score = 58.4 bits (140), Expect = 5e-09, Method: Composition-based stats. Identities = 60/363 (16%), Positives = 132/363 (36%), Gaps = 57/363 (15%) Query: 72 VIAQAQSGTGKTATFAIS--ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGA 129 +I ++G+GKT + +++ D Q + P R A V + D M Sbjct: 242 LIIMGETGSGKTT--QLPQYLVEDGFTDQGKLQIAITQPRRVAAT---SVAARVADEMN- 295 Query: 130 SCHACIGGTNVRAEVQKLQMEAPHIIVG---TPGRVFD-MLNRRYLSPKYIKMFVLDEAD 185 + G V +++ P+ V T G + L LS M +DEA Sbjct: 296 ----VVLGKEVGYQIRFEDKTTPNKTVLKYMTDGMLLREFLTDSKLSKYSCIM--IDEAH 349 Query: 186 -EMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLE 244 L+ + ++++ SATM + + ++ F PI + + Sbjct: 350 ERTLATDILIGLLKDILPQRPTLKLLISSATM--NAKKFSEFFDNCPIFNVPGRRYPVD- 406 Query: 245 GIRQFYINVERE--EWKLDTLCDLYETLTITQAV-IFI-------NTRRKVDWLTEKM-- 292 + + E + T+ ++ T ++ + +F+ T+ K++ + K+ Sbjct: 407 --IHYTLQPEANYIHAAITTIFQIHTTQSLPGDILVFLTGQEEIERTKTKLEEIMSKLGS 464 Query: 293 HARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVIN------ 346 + ++ ++ ++ Q+++ I + +V++ T++ + + + VI+ Sbjct: 465 RTKQMIITPIYANLPQEQQLKIFQPTPENCRKVVLATNIAETSLTIDGIRYVIDPGFVKE 524 Query: 347 ------------YDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTS 394 +P +R + R GR GR G G + T+ L ++E Sbjct: 525 NSYVPSTGMTQLLTVPCSRASVDQRAGRAGRVG-PGKCFRIFTK--WSYLHELELMPKPE 581 Query: 395 IEE 397 I Sbjct: 582 ITR 584 >6BOG-A nrPDB Length = 968 Score = 58.1 bits (139), Expect = 7e-09, Method: Composition-based stats. Identities = 35/183 (19%), Positives = 71/183 (38%), Gaps = 12/183 (6%) Query: 191 GF-KDQIYDIFQKLNSNTQVVL-LSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQ 248 GF K +++ I L + Q + +S M + + RD + +E + Sbjct: 427 GFPKRELHTIKLPLPTQYQTAIKVSGIM--GARKSAEDRARDMLYPERIYQEFEGDNATW 484 Query: 249 FYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHAR-DFTVSAMHGDMD 307 + + +++ L + + ++ L + + R + H M Sbjct: 485 W-----NFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMS 539 Query: 308 QKERDVIMREFRSGS--SRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGR 365 ERD F ++VL+ +++ + G + Q S ++ +DLP N + RIGR R Sbjct: 540 IIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDR 599 Query: 366 FGR 368 G+ Sbjct: 600 IGQ 602 Score = 36.1 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 35/202 (17%), Positives = 65/202 (32%), Gaps = 34/202 (16%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G GKT + IL Q L A + L++ P Q + ++ + Sbjct: 180 GLGKTIEAGM-ILHQQLLSGAAERVLIIVPE---TLQ-HQWLVEMLRRFNLRFALFDDER 234 Query: 139 NVRAEVQKLQ-MEAPHIIVGTPGRVFDMLNRRYLSPKYIK-----MFVLDEADEMLSRGF 192 A+ + +++ + D R +++ + V+DEA ++ Sbjct: 235 YAEAQHDAYNPFDTEQLVICS----LDFARRSKQRLEHLCEAEWDLLVVDEAHHLV--WS 288 Query: 193 KD----QIYDIFQKLNSNTQVVLLSATMPSDV---LEVTKKFMRDPIRILVKKEELTLEG 245 +D + I Q V+LL+AT P + + + DP R Sbjct: 289 EDAPSREYQAIEQLAEHVPGVLLLTAT-PEQLGMESHFARLRLLDPNR---------FHD 338 Query: 246 IRQFYINVEREEWKLDTLCDLY 267 QF + D + L Sbjct: 339 FAQFVEEQKNYRPVADAVAMLL 360 >5FMF-1 nrPDB Length = 492 Score = 57.3 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 50/361 (13%), Positives = 112/361 (31%), Gaps = 55/361 (15%) Query: 56 SAIQQRAILPCI---KGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTREL 112 Q++++ + I G GKT + + +VL + Sbjct: 70 RPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKS------VIVLCTSSVS 123 Query: 113 AQQIQKVVMALGDYMGASCHACIGGTNVRAEVQK-LQMEAPHIIVGTPGRVFDMLN-RRY 170 Q ++ + +C + + L + ++ T R D + Sbjct: 124 VMQWRQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDF 183 Query: 171 LSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVT------ 224 L+ + +LDE + + F+ + I + L+AT+ + ++ Sbjct: 184 LTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAK-----LGLTATLVREDDKIGDLNFLI 238 Query: 225 ------KKFM---RDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDL--------- 266 +M + V+ E+ +FY RE + L + Sbjct: 239 GPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQAC 298 Query: 267 -----YETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFR-S 320 Y + ++F + + KM ++G Q+ER I++ F+ + Sbjct: 299 QFLIQYHERRGDKIIVFSDNVYALQEYALKMGKP-----FIYGSTPQQERMNILQNFQYN 353 Query: 321 GSSRVLITTDLLARGIDVQQVSLVI----NYDLPTNRENYIHRIGRGGRFGRKGVAINMV 376 + + + ID+ + + +I +Y + RI R R +G Sbjct: 354 DQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFY 413 Query: 377 T 377 + Sbjct: 414 S 414 >6I3O-A nrPDB Length = 677 Score = 57.3 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 66/353 (18%), Positives = 127/353 (35%), Gaps = 53/353 (15%) Query: 61 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLA--PTRELAQQIQK 118 + I +I ++G+GKT + Q + ++ P R A + K Sbjct: 20 QIIQAVKDNQILIVVGETGSGKT----TQVTQYLAEAGFTKYGMIGCTQPRRVAAVSVAK 75 Query: 119 -VVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYL---SPK 174 V +G +G I +V + K++ ML R L K Sbjct: 76 RVAEEVGCQLGQEVGYTIRFEDVTSPATKIKYMTD-----------GMLQREILMDPDLK 124 Query: 175 YIKMFVLDEAD-EMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIR 233 + +LDEA ++ + K + +V++ SAT+ D + ++ F PI Sbjct: 125 RYSVIMLDEAHERTIATDVLFALLKKTVKRRPDLKVIVTSATL--DAEKFSEYFNSCPIF 182 Query: 234 ILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRK----VDWLT 289 + + +E + + E L T+ ++ T ++F+ + + + L Sbjct: 183 TIPGRT-FPVEILYSREPEPDYLEAALTTVMQIHLTEPPGDILVFLTGQEEIDTACEILY 241 Query: 290 EKMHARDFTVSA-----MHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLV 344 E+M A +V ++ + + + I GS +V+I T++ I + + V Sbjct: 242 ERMKALGPSVPELIILPIYSALPSEMQSRIFEPAPPGSRKVVIATNIAETSITIDYIYYV 301 Query: 345 IN--------YDL----------PTNRENYIHRIGRGGRFGRKGVAINMVTEE 379 ++ YD P ++ R GR GR G G + TE Sbjct: 302 VDPGFVKQNAYDPKLGMDSLVVTPISQAQANQRAGRAGRTG-PGKCFRLYTEA 353 >5SVA-Z nrPDB Length = 843 Score = 57.3 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 50/361 (13%), Positives = 112/361 (31%), Gaps = 55/361 (15%) Query: 56 SAIQQRAILPCI---KGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTREL 112 Q++++ + I G GKT + + +VL + Sbjct: 363 RPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKS------VIVLCTSSVS 416 Query: 113 AQQIQKVVMALGDYMGASCHACIGGTNVRAEVQK-LQMEAPHIIVGTPGRVFDMLN-RRY 170 Q ++ + +C + + L + ++ T R D + Sbjct: 417 VMQWRQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDF 476 Query: 171 LSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVT------ 224 L+ + +LDE + + F+ + I + L+AT+ + ++ Sbjct: 477 LTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAK-----LGLTATLVREDDKIGDLNFLI 531 Query: 225 ------KKFM---RDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDL--------- 266 +M + V+ E+ +FY RE + L + Sbjct: 532 GPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQAC 591 Query: 267 -----YETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFR-S 320 Y + ++F + + KM ++G Q+ER I++ F+ + Sbjct: 592 QFLIQYHERRGDKIIVFSDNVYALQEYALKMGKP-----FIYGSTPQQERMNILQNFQYN 646 Query: 321 GSSRVLITTDLLARGIDVQQVSLVI----NYDLPTNRENYIHRIGRGGRFGRKGVAINMV 376 + + + ID+ + + +I +Y + RI R R +G Sbjct: 647 DQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFY 706 Query: 377 T 377 + Sbjct: 707 S 707 >3B6E-A nrPDB Length = 216 Score = 56.1 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 21/140 (15%), Positives = 49/140 (35%), Gaps = 10/140 (7%) Query: 56 SAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLK---ATQALVLAPTREL 112 Q P ++G ++I +G+GKT ++ K + +VL L Sbjct: 35 RPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLL 94 Query: 113 AQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTP----GRVFDMLNR 168 +Q+ + G T ++ ++ +++ II+ T + ++ N Sbjct: 95 VEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEV-VKSCDIIISTAQILENSLLNLENG 153 Query: 169 R--YLSPKYIKMFVLDEADE 186 + + ++DE Sbjct: 154 EDAGVQLSDFSLIIIDECHH 173 >3RC8-A nrPDB Length = 677 Score = 53.0 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 24/154 (15%), Positives = 58/154 (37%), Gaps = 20/154 (12%) Query: 260 LDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFR 319 LD + + L ++ ++ + ++ ++ R + ++G + + ++F Sbjct: 309 LDHALESLDNLRPGDCIV-CFSKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQAKKFN 367 Query: 320 --SGSSRVLITTDLLARGIDVQQVSLVINYDL--------------PTNRENYIHRIGRG 363 + ++L+ TD + G+++ + +I Y L P + GR Sbjct: 368 DPNDPCKILVATDAIGMGLNLS-IRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRA 426 Query: 364 GRFGRKGV--AINMVTEEDKRTLRDIETFYNTSI 395 GRF + + + ED L++I I Sbjct: 427 GRFSSRFKEGEVTTMNHEDLSLLKEILKRPVDPI 460 >3MWY-W nrPDB Length = 800 Score = 52.7 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 59/152 (38%), Gaps = 12/152 (7%) Query: 259 KLDTLCDLYETLTIT--QAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMR 316 K+ L L L + +IF R +D L + + + + G + +R + + Sbjct: 557 KMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRISID 616 Query: 317 EFRSGSSR---VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAI 373 F S S L++T GI++ V+ +D N + + + R R G+K + Sbjct: 617 HFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKNHVM 676 Query: 374 NM--VTEEDKRTLRDIETFYNTSIEEMPLNVA 403 V+++ E + ++M L A Sbjct: 677 VYRLVSKDTVE-----EEVLERARKKMILEYA 703 >6ID1-V nrPDB Length = 795 Score = 52.3 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 53/400 (13%), Positives = 139/400 (34%), Gaps = 59/400 (14%) Query: 25 SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPS-AIQQRAILPCIKGYDVIAQAQSGTGKT 83 ++ + ++ F ++ + I + P + R ++ + ++G+GKT Sbjct: 109 TSLPQCINPFTNLPHTPRYYD-ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKT 167 Query: 84 ATFAIS--ILQQIELDLKATQAL-VLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNV 140 I ++ + + + P R A V + D M +G + Sbjct: 168 T--QIPQWCVEYMRSLPGPKRGVACTQPRRVAAM---SVAQRVADEMDVMLGQEVGYSIR 222 Query: 141 RAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD-EMLSRGFKDQIYDI 199 + + ++ T G + L + + +LDEA L+ + Sbjct: 223 FEDCSSAKTILKYM---TDGMLLREAMNDPL-LERYGVIILDEAHERTLATDILMGVLKE 278 Query: 200 FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWK 259 + S+ +V+++SAT+ D + F P+ + + + FY ++ Sbjct: 279 VVRQRSDLKVIVMSATL--DAGKFQIYFDNCPLLTIPGR----THPVEIFYTPEPERDYL 332 Query: 260 LDTLCDLYETL----TITQAVIFINTRRKVDWLTEKMHAR---------DFTVSAMHGDM 306 + + + ++F+ + ++D +++ D + ++ + Sbjct: 333 EAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTL 392 Query: 307 DQKERDVIMR----EFRSGSS--RVLITTDLLARGIDVQQVSLVINYDLPT--------- 351 +++ I + ++G+ +V+++T++ + + V VI+ Sbjct: 393 PPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIR 452 Query: 352 ---------NRENYIHRIGRGGRFGRKGVAINMVTEEDKR 382 ++ + R GR GR R G + TE+ + Sbjct: 453 VESLLVTAISKASAQQRAGRAGR-TRPGKCFRLYTEKAYK 491 >3H1T-A nrPDB Length = 590 Score = 52.3 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 63/423 (14%), Positives = 131/423 (30%), Gaps = 83/423 (19%) Query: 15 DGMEPEGVIESNWNEIVDSFD----DMNLSES----LLRGIYAYGFEKPSAIQQRAILPC 66 D E + S + + F D + + LL + P QQ AI Sbjct: 131 DYTTGEEQLLSRFPTPDELFKRLCGDEGIKDEDLDTLLSPYHHVSGYSPRYYQQIAINRA 190 Query: 67 ----IKG--YDVIAQAQSGTGKTA-TFAIS-----ILQQIELDLKATQALVLAPTRELAQ 114 ++G +I A +GTGKT F IS D + + L LA L Sbjct: 191 VQSVLQGKKRSLITMA-TGTGKTVVAFQISWKLWSARWNRTGDYRKPRILFLADRNVLVD 249 Query: 115 QIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPK 174 + G + H GG V++ + + + R + Sbjct: 250 DPKD---KTFTPFGDARHKIEGGKVVKSREIYFAIYQS---IASDERRPGLYKE--FPQD 301 Query: 175 YIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRI 234 + + ++DE +R +I + Q+ ++AT + T ++ +PI Sbjct: 302 FFDLIIIDECHRGSARD-NSNWREILEYFEPAFQI-GMTATPLREDNRDTYRYFGNPIYT 359 Query: 235 LVKKEELTLEGIRQFYIN------------------------------VEREEWKLDTLC 264 ++ + + + ++ ++ ++ L Sbjct: 360 YSLRQGIDDGFLAPYRVHRVISEVDAAGWRPSKGDVDRFGREIPDGEYQTKDFERVIALK 419 Query: 265 D------------LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMH----GDMDQ 308 + T + ++F + D + ++ + +S H + Sbjct: 420 ARTDAFAKHLTDFMKRTDRFAKTIVFCVDQEHADEMRRALNNLNSDLSRKHPDYVARVTS 479 Query: 309 KE------RDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 362 +E +E + + +L T+ LL G+D V+ + + + +GR Sbjct: 480 EEGKIGKGHLSRFQELETSTPVILTTSQLLTTGVDAPTCKNVVLARVVNSMSEFKQIVGR 539 Query: 363 GGR 365 G R Sbjct: 540 GTR 542 >6FA9-A nrPDB Length = 655 Score = 52.3 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 56/343 (16%), Positives = 116/343 (33%), Gaps = 54/343 (15%) Query: 72 VIAQAQSGTGKTATFAIS-ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGAS 130 +I ++G+GKT I L + + P R A V + D MG Sbjct: 50 LILVGETGSGKTT--QIPQYLHEAGYTKGNRKIACTQPRRVAAM---SVAARVADEMGVR 104 Query: 131 CHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR 190 +G + E + T G + + ++DEA E Sbjct: 105 LGHEVG---YSIRFEDCTSEKTILKYMTDGMLLREMVT-SPDLADYSCIMIDEAHE--RT 158 Query: 191 GFKDQIYDIFQKLNSNTQVVLL---SATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIR 247 D + + + L + L SAT+ + + + F PI + + + + Sbjct: 159 VHTDILLALIKDLTRARPELRLIISSATL--NAEKFSAYFDDAPIFNVPGR----VHPVE 212 Query: 248 QFYINVERE---EWKLDTLCDLYETLTITQAVIFI-------NTRRKVDWLTEKMHAR-- 295 +Y + E L T+ ++ T ++F+ +V+ + K+ R Sbjct: 213 VYYTSAPESNYLEAALVTVFQIHATQPEGDILVFLTGQEEIERACERVEEIRRKLGKRVP 272 Query: 296 DFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYD------- 348 + ++ +M + + I G+ +V+ +T++ + + + VI+ Sbjct: 273 EIIALPIYSNMPSEMQAKIFEPTPPGARKVVFSTNIAETSLTIDGIVYVIDSGYVKENTF 332 Query: 349 -------------LPTNRENYIHRIGRGGRFGRKGVAINMVTE 378 +P +R R+GR GR + G + T+ Sbjct: 333 SPVGTTGQSTLAVVPCSRAAANQRMGRAGRV-KPGKCFRLYTK 374 >6FTX-W nrPDB Length = 878 Score = 51.9 bits (123), Expect = 4e-07, Method: Composition-based stats. Identities = 31/169 (18%), Positives = 63/169 (37%), Gaps = 19/169 (11%) Query: 244 EGIRQFYINVER-------EEWKLDTLCDLYETLTIT--QAVIFINTRRKVDWLTEKMHA 294 E + Q ++ E K+ L L L + +IF R +D L + + Sbjct: 479 ERVLQKFMTRENVLRGLIMSSGKMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSI 538 Query: 295 RDFTVSAMHGDMDQKERDVIMREFRSGSSR---VLITTDLLARGIDVQQVSLVINYDLPT 351 + + G + +R + + F S S L++T GI++ V+ +D Sbjct: 539 KGINFQRLDGTVPSAQRRISIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDW 598 Query: 352 NRENYIHRIGRGGRFGRKGVAINM--VTEEDKRTLRDIETFYNTSIEEM 398 N + + + R R G+K + V+++ E + ++M Sbjct: 599 NPQADLQAMARAHRIGQKNHVMVYRLVSKDTVE-----EEVLERARKKM 642 >5K8T-A nrPDB Length = 458 Score = 51.5 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 49/310 (15%), Positives = 106/310 (34%), Gaps = 67/310 (21%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALG-DYMGASCHACIGG 137 G GKT + + + E + ++LAPTR +A ++++ + L YM + + G Sbjct: 34 GAGKTRR-VLPEIVR-EAIKTRLRTVILAPTRVVAAEMEEALRGLPVRYMTTAVNVTHSG 91 Query: 138 TNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD-----EMLSRGF 192 T + + H + R+ + + +++DEA + +RG+ Sbjct: 92 TEIVDLM-------CHATFTS--RLLQPIRVPNYNL-----YIMDEAHFTDPSSIAARGY 137 Query: 193 KDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYIN 252 ++ + + ++AT P T+ D ++ E Sbjct: 138 ISTRVEMGEA-----AAIFMTATPPG-----TRDAFPDSNSPIMDTE------------- 174 Query: 253 VEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERD 312 VE E + D + V F+ + R + + + V + + E Sbjct: 175 VEVPERAWSSGFDWVTDHSGK-TVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETE-- 231 Query: 313 VIMREFRSGSSRVLITTDLLARGIDVQQVSLV--------INYD---------LPTNREN 355 ++ + ++TTD+ G + + ++ + D +P + Sbjct: 232 --FQKTKHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHAS 289 Query: 356 YIHRIGRGGR 365 R GR GR Sbjct: 290 AAQRRGRIGR 299 >3DIN-A nrPDB Length = 871 Score = 51.5 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 25/135 (18%), Positives = 54/135 (40%), Gaps = 12/135 (8%) Query: 257 EWKLDTLCDLYET--LTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVI 314 + K + + + E ++ + K + L+ + + ++ +KE +++ Sbjct: 457 KEKYEKIVEEIEKRYKKGQPVLVGTTSIEKSELLSSMLKKKGIPHQVLNAKYHEKEAEIV 516 Query: 315 MREFRSGSSRVLITTDLLARGIDV---QQVS-----LVINYDLPTNRENYIHRIGRGGRF 366 + + G V I T++ RG D+ V+ +I + +R GR GR Sbjct: 517 AKAGQKGM--VTIATNMAGRGTDIKLGPGVAELGGLCIIGTERHESRRIDNQLRGRAGRQ 574 Query: 367 GRKGVAINMVTEEDK 381 G G +I ++ ED Sbjct: 575 GDPGESIFFLSLEDD 589 Score = 34.2 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 22/57 (38%), Gaps = 5/57 (8%) Query: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90 F+ L R +P +Q + +G +A+ ++G GKT + I Sbjct: 58 FEAFALVREAARRTLGM---RPFDVQVMGGIALHEGK--VAEMKTGEGKTLAATMPI 109 >5XDR-A nrPDB Length = 690 Score = 51.1 bits (121), Expect = 9e-07, Method: Composition-based stats. Identities = 53/397 (13%), Positives = 137/397 (34%), Gaps = 59/397 (14%) Query: 28 NEIVDSFDDMNLSESLLRGIYAYGFEKPS-AIQQRAILPCIKGYDVIAQAQSGTGKTATF 86 + ++ F ++ + I + P + R ++ + ++G+GKT Sbjct: 7 PQCINPFTNLPHTPRYYD-ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTT-- 63 Query: 87 AIS--ILQQIELDLKATQAL-VLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAE 143 I ++ + + + P R A V + D M +G + + Sbjct: 64 QIPQWCVEYMRSLPGPKRGVACTQPRRVAAM---SVAQRVADEMDVMLGQEVGYSIRFED 120 Query: 144 VQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD-EMLSRGFKDQIYDIFQK 202 + ++ T G + L + + +LDEA L+ + + Sbjct: 121 CSSAKTILKYM---TDGMLLREAMNDPL-LERYGVIILDEAHERTLATDILMGVLKEVVR 176 Query: 203 LNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDT 262 S+ +V+++SAT+ D + F P+ + + + FY ++ Sbjct: 177 QRSDLKVIVMSATL--DAGKFQIYFDNCPLLTIPGR----THPVEIFYTPEPERDYLEAA 230 Query: 263 LCDLYETL----TITQAVIFINTRRKVDWLTEKMHAR---------DFTVSAMHGDMDQK 309 + + + ++F+ + ++D +++ D + ++ + + Sbjct: 231 IRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQ 290 Query: 310 ERDVIMR----EFRSGSS--RVLITTDLLARGIDVQQVSLVINYDLPT------------ 351 ++ I + ++G+ +V+++T++ + + V VI+ Sbjct: 291 QQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVES 350 Query: 352 ------NRENYIHRIGRGGRFGRKGVAINMVTEEDKR 382 ++ + R GR GR R G + TE+ + Sbjct: 351 LLVTAISKASAQQRAGRAGR-TRPGKCFRLYTEKAYK 386 >5JXR-A nrPDB Length = 723 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 59/153 (38%), Gaps = 12/153 (7%) Query: 256 EEWKLDTLCDLYETLT--ITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDV 313 K+ L L + + ++ +IF R +D L + R + + G ++R Sbjct: 408 NAGKMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYKYCRIDGSTAHEDRIA 467 Query: 314 IMREFR---SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKG 370 + E+ S L+TT GI++ +VI YD N + + + R R G+ Sbjct: 468 AIDEYNKPGSDKFIFLLTTRAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQTK 527 Query: 371 VAIN--MVTEEDKRTLRDIETFYNTSIEEMPLN 401 + VT+ E + +++ L+ Sbjct: 528 QVVVYRFVTDNAIE-----EKVLERAAQKLRLD 555 >4OK6-A nrPDB Length = 464 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 52/269 (19%), Positives = 92/269 (34%), Gaps = 64/269 (23%) Query: 76 AQSGTGKT----ATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASC 131 A +G+GK+ A +A + + LVL P+ + G YM + Sbjct: 38 APTGSGKSTKVPAAYA----------AQGYKVLVLNPS-------VAATLGFGAYM-SKA 79 Query: 132 HACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADE----- 186 H N+R V+ + +P I T G+ L S + + DE Sbjct: 80 HGV--DPNIRTGVRTITTGSP-ITYSTYGK---FLADGGCSGGAYDIIICDECHSTDATS 133 Query: 187 MLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGI 246 +L G + VVL +AT P ++ I Sbjct: 134 ILGIGTVLD----QAETAGARLVVLATATPP-------------------GSVTVSHPNI 170 Query: 247 RQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDM 306 + ++ E L E + + +IF ++++K D L K+ A A + + Sbjct: 171 EEVALSTTGEIPFYGKAIPL-EVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYRGL 229 Query: 307 DQKERDVIMREFRSGSSRVLITTDLLARG 335 D ++ +G V+++TD L G Sbjct: 230 D----VSVIPT--NGDV-VVVSTDALMTG 251 >5JXT-B nrPDB Length = 349 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 59/153 (38%), Gaps = 12/153 (7%) Query: 256 EEWKLDTLCDLYETLT--ITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDV 313 K+ L L + + ++ +IF R +D L + R + + G ++R Sbjct: 83 NAGKMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYKYCRIDGSTAHEDRIA 142 Query: 314 IMREFR---SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKG 370 + E+ S L+TT GI++ +VI YD N + + + R R G+ Sbjct: 143 AIDEYNKPGSDKFIFLLTTRAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQTK 202 Query: 371 VAIN--MVTEEDKRTLRDIETFYNTSIEEMPLN 401 + VT+ E + +++ L+ Sbjct: 203 QVVVYRFVTDNAIE-----EKVLERAAQKLRLD 230 >4B6E-A nrPDB Length = 683 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 51/269 (18%), Positives = 87/269 (32%), Gaps = 64/269 (23%) Query: 76 AQSGTGKT----ATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASC 131 A +G+GK+ A +A + + LVL P+ + G YM + Sbjct: 239 APTGSGKSTKVPAAYA----------AQGYKVLVLNPS-------VAATLGFGAYM-SKA 280 Query: 132 HACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADE----- 186 H N+R V+ + AP + T G+ L S + + DE Sbjct: 281 HGI--DPNIRTGVRTITTGAP-VTYSTYGK---FLADGGCSGGAYDIIICDECHSTDSTT 334 Query: 187 MLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGI 246 +L G + VVL +AT P + I Sbjct: 335 ILGIGTVLD----QAETAGARLVVLATATPP-------------------GSVTVPHPNI 371 Query: 247 RQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDM 306 + ++ E + E + + +IF ++++K D L K+ A + + Sbjct: 372 EEVALSNTGEIPFYGKAIPI-EAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRGL 430 Query: 307 DQKERDVIMREFRSGSSRVLITTDLLARG 335 D I G V++ TD L G Sbjct: 431 DVSVIPTI------GDV-VVVATDALMTG 452 >2ZJO-A nrPDB Length = 482 Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 54/269 (20%), Positives = 92/269 (34%), Gaps = 64/269 (23%) Query: 76 AQSGTGKT----ATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASC 131 A +G+GK+ A +A + + LVL P+ + G YM + Sbjct: 49 APTGSGKSTKVPAAYA----------AQGYKVLVLNPS-------VAATLGFGAYM-SKA 90 Query: 132 HACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADE----- 186 H N+R V+ + AP I T G+ L S + + DE Sbjct: 91 HGV--DPNIRTGVRTITTGAP-ITYSTYGK---FLADGGCSGGAYDIIMCDECHSTDSTT 144 Query: 187 MLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGI 246 +L G + VVL +AT P + I Sbjct: 145 ILGIGTVLD----QAETAGARLVVLATATPP-------------------GSVTVPHPNI 181 Query: 247 RQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDM 306 + ++ E + ET+ + +IF ++++K D L K+ A A + + Sbjct: 182 EEIALSNTGEIPFYGKAIPI-ETIKGGRHLIFCHSKKKCDELAAKLSALGIHAVAYYRGL 240 Query: 307 DQKERDVIMREFRSGSSRVLITTDLLARG 335 D ++ SG+ V++ TD L G Sbjct: 241 D----VSVIPA--SGNV-VVVATDALMTG 262 >2BMF-A nrPDB Length = 451 Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 48/320 (15%), Positives = 107/320 (33%), Gaps = 85/320 (26%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G GKT + + + + E + + L+LAPTR +A ++++ + G Sbjct: 29 GAGKTKRY-LPAIVR-EAIKRGLRTLILAPTRVVAAEMEEALR---------------GL 71 Query: 139 NVRAEVQKLQMEAPHIIVGTPGR-VFDMLNRRYLSPKYIK--------MFVLDEAD---- 185 +R + ++ E GR + D++ + + + + ++DEA Sbjct: 72 PIRYQTPAIRAEHT-------GREIVDLMCHATFTMRLLSPIRVPNYNLIIMDEAHFTDP 124 Query: 186 -EMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLE 244 + +RG+ ++ + + ++AT P + I+ ++ E+ Sbjct: 125 ASIAARGYISTRVEMGEA-----AGIFMTATPPGSRDPFPQSNAP----IMDEEREIPER 175 Query: 245 GIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHG 304 + V + K V F+ + + + + + V + Sbjct: 176 SWNSGHEWVTDFKGK---------------TVWFVPSIKAGNDIAACLRKNGKKVIQLSR 220 Query: 305 DMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSL---------VINYD------- 348 E + R+ ++TTD+ G + + + VI D Sbjct: 221 KTFDSE----YIKTRTNDWDFVVTTDISEMGANFKAERVIDPRRCMKPVILTDGEERVIL 276 Query: 349 ---LPTNRENYIHRIGRGGR 365 +P + R GR GR Sbjct: 277 AGPMPVTHSSAAQRRGRVGR 296 >2QEQ-A nrPDB Length = 434 Score = 49.6 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 48/314 (15%), Positives = 100/314 (31%), Gaps = 73/314 (23%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G GKT I++ E + + VLAPTR +A ++ + + L S A Sbjct: 12 GAGKTRRILPQIIK--EAINRRLRTAVLAPTRVVAAEMAEALRGLPIRYQTSAVA----- 64 Query: 139 NVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYI---KMFVLDEAD-----EMLSR 190 ++ H T L R +SP + +FV+DEA + +R Sbjct: 65 -REHNGNEIVDVMCH---AT-------LTHRLMSPHRVPNYNLFVMDEAHFTDPASIAAR 113 Query: 191 GFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFY 250 G+ ++ + + ++AT P + + + Sbjct: 114 GYISTRVELGEA-----AAIFMTATPPGTSDPF------------PESNAPISDLQTEIP 156 Query: 251 INVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKE 310 + + E I + V F+ + + + + + V ++ + E Sbjct: 157 -----DRAWNSGYEWITEY--IGKTVWFVPSVKMGNEIALCLQRAGKKVIQLNRKSYETE 209 Query: 311 RDVIMREFRSGSSRVLITTDLLARGIDVQQVSLV-----------------INYDLPT-- 351 + ++ ++TTD+ G + + ++ + P+ Sbjct: 210 ----YPKCKNDDWDFVVTTDISEMGANFKASRVIDSRKSVKPTIITEGEGRVILGEPSAV 265 Query: 352 NRENYIHRIGRGGR 365 + R GR GR Sbjct: 266 TAASAAQRRGRTGR 279 >2Z83-A nrPDB Length = 459 Score = 48.0 bits (113), Expect = 6e-06, Method: Composition-based stats. Identities = 52/314 (16%), Positives = 100/314 (31%), Gaps = 73/314 (23%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G+GKT I++ + + + VLAPTR +A ++ + + L S Sbjct: 31 GSGKTRKILPQIIK--DAIQQRLRTAVLAPTRVVAAEMAEALRGLPVRYQTSAV------ 82 Query: 139 NVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYI---KMFVLDEAD-----EMLSR 190 + ++ H T L R +SP + +FV+DEA + +R Sbjct: 83 QREHQGNEIVDVMCH---AT-------LTHRLMSPNRVPNYNLFVMDEAHFTDPASIAAR 132 Query: 191 GFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFY 250 G+ ++ + + ++AT P I ++E+ Y Sbjct: 133 GYIATKVELGEA-----AAIFMTATPPGTTDPFPDSNAP----IHDLQDEIPDRAWSSGY 183 Query: 251 INVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKE 310 + K V F+ + + + + + V ++ E Sbjct: 184 EWITEYAGK---------------TVWFVASVKMGNEIAMCLQRAGKKVIQLNRKSYDTE 228 Query: 311 RDVIMREFRSGSSRVLITTDLLARGIDVQQVSL------------------VINYDL-PT 351 + ++G +ITTD+ G + + VI + P Sbjct: 229 ----YPKCKNGDWDFVITTDISEMGANFGASRVIDCRKSVKPTILEEGEGRVILGNPSPI 284 Query: 352 NRENYIHRIGRGGR 365 + R GR GR Sbjct: 285 TSASAAQRRGRVGR 298 >5X0Y-O nrPDB Length = 735 Score = 48.0 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 46/116 (39%), Gaps = 5/116 (4%) Query: 259 KLDTLCDLYETL--TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMR 316 K + L + L T + +IF + +D + + + + + G ER ++R Sbjct: 423 KFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLR 482 Query: 317 EFRSGSSRVLI---TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRK 369 F + S L +T G+++Q VI +D N + R R G+K Sbjct: 483 LFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQK 538 >2JLW-A nrPDB Length = 451 Score = 47.7 bits (112), Expect = 8e-06, Method: Composition-based stats. Identities = 47/313 (15%), Positives = 98/313 (31%), Gaps = 71/313 (22%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G GKT + + + E + + L+LAPTR +A ++++ + L Sbjct: 29 GAGKTKR-ILPSIVR-EALKRRLRTLILAPTRVVAAEMEEALRGLPIRYQTPAVK----- 81 Query: 139 NVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD-----EMLSRGFK 193 +++ H T R+ + V+DEA + +RG+ Sbjct: 82 -SDHTGREIVDLMCHATFTT--RLLSSTRVPNYNL-----IVMDEAHFTDPCSVAARGYI 133 Query: 194 DQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINV 253 ++ + + ++AT P + + +E I Sbjct: 134 STRVEMGEA-----AAIFMTATPPGSIDPFPQS-------------NSPIEDIE------ 169 Query: 254 EREEWKLDTLCDLYETLTITQA--VIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKER 311 E + ++ +T Q V F+ + + + + + V + E Sbjct: 170 --REIPERSWNTGFDWITDYQGKTVWFVPSIKAGNDIANCLRKSGKRVIQLSRKTFDTE- 226 Query: 312 DVIMREFRSGSSRVLITTDLLARGIDVQQVSL---------VINYD----------LPTN 352 + + ++TTD+ G + + + VI D +P Sbjct: 227 ---YPKTKLTDWDFVVTTDISEMGANFRAGRVIDPRRCLKPVILTDGPERVILAGPIPVT 283 Query: 353 RENYIHRIGRGGR 365 + R GR GR Sbjct: 284 PASAAQRRGRIGR 296 >4UAQ-A nrPDB Length = 778 Score = 47.7 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 41/259 (15%), Positives = 95/259 (36%), Gaps = 39/259 (15%) Query: 147 LQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR---GFKDQIYDIFQKL 203 ++ +A H+I + GR+ + P ++ V EA E + G + + Sbjct: 321 VRDDAVHLINASRGRIAQLQRW----PDGLQAAV--EAKEGIETTETGEVLDTITVQALI 374 Query: 204 NSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQ------FYINVEREE 257 N V ++ T + +R ++ V IR+ + + + Sbjct: 375 NRYATVCGMTGTA-----LAAGEQLRQFYQLGVSPIPPNKPNIREDEADRVYITTAAKND 429 Query: 258 WKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMRE 317 ++ + ++++ ++ + + L E++ R ++ D +E VI Sbjct: 430 GIVEHITEVHQRGQ--PVLVGTRDVAESEELHERLVRRGVPAVVLNAKNDAEEARVIAEA 487 Query: 318 FRSGSSRVLITTDLLARGIDVQ----------QVSLVINYDLPTNRENYIHR-----IGR 362 + G+ V ++T + RG D++ +V+ + + ++ R GR Sbjct: 488 GKYGA--VTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGR 545 Query: 363 GGRFGRKGVAINMVTEEDK 381 GR G G ++ + ED Sbjct: 546 AGRQGDPGSSVFFSSWEDD 564 Score = 28.4 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 13/36 (36%) Query: 282 RRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMRE 317 RR +W+ + A TV + D ER Sbjct: 144 RRDAEWMGPLLDAMGLTVGWITADSTPDERRTAYDR 179 >2WZQ-A nrPDB Length = 619 Score = 47.3 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 47/313 (15%), Positives = 97/313 (30%), Gaps = 71/313 (22%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G GKT + + + E + + L+LAPTR +A ++++ + L Sbjct: 197 GAGKTKR-ILPSIVR-EALKRRLRTLILAPTRVVAAEMEEALRGLPIRYQTPAVK----- 249 Query: 139 NVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD-----EMLSRGFK 193 +++ H T R+ + V+DEA + +RG+ Sbjct: 250 -SDHTGREIVDLMCHATFTT--RLLSSTRVPNYNL-----IVMDEAHFTDPCSVAARGYI 301 Query: 194 DQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINV 253 ++ + + ++AT P + +E I Sbjct: 302 STRVEMGEA-----AAIFMTATPPGSTDPFPQS-------------NSPIEDIE------ 337 Query: 254 EREEWKLDTLCDLYETLTITQA--VIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKER 311 E + ++ +T Q V F+ + + + + + V + E Sbjct: 338 --REIPERSWNTGFDWITDYQGKTVWFVPSIKAGNDIANCLRKSGKRVIQLSRKTFDTE- 394 Query: 312 DVIMREFRSGSSRVLITTDLLARGIDVQQVSL---------VINYD----------LPTN 352 + + ++TTD+ G + + + VI D +P Sbjct: 395 ---YPKTKLTDWDFVVTTDISEMGANFRAGRVIDPRRCLKPVILTDGPERVILAGPIPVT 451 Query: 353 RENYIHRIGRGGR 365 + R GR GR Sbjct: 452 PASAAQRRGRIGR 464 >5HZR-A nrPDB Length = 732 Score = 47.3 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 46/116 (39%), Gaps = 5/116 (4%) Query: 259 KLDTLCDLY--ETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMR 316 K + L + T + ++F +D + + + R + G ++R ++R Sbjct: 430 KFELLDRILPKYKATGHRVLMFFQMTAIMDIMEDFLRFRGLHYLRLDGTTKSEDRSELLR 489 Query: 317 EFRSGSSR---VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRK 369 +F S L++T G+++Q VI YD N + R R G+K Sbjct: 490 QFNQPDSPYFMFLLSTRAGGLGLNLQTADTVIIYDSDWNPHQDLQAQDRAHRIGQK 545 >1YKS-A nrPDB Length = 440 Score = 46.9 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 50/311 (16%), Positives = 98/311 (31%), Gaps = 68/311 (21%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G GKT F IL E + + LVLAPTR + ++++ L + G Sbjct: 18 GAGKTRRFLPQIL--AECARRRLRTLVLAPTRVVLSEMKEAFHGLDVKFHTQAFSAHGSG 75 Query: 139 NVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD-----EMLSRGFK 193 R + + + P RV + ++ ++DEA + +RG+ Sbjct: 76 --REVIDAMCHATLTYRMLEPTRVVNW-----------EVIIMDEAHFLDPASIAARGW- 121 Query: 194 DQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINV 253 + + + +L++AT P +E + Sbjct: 122 ----AAHRARANESATILMTATPPGT------------------SDEFPHSNGEIEDVQT 159 Query: 254 E-REEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERD 312 + E + T F+ + R + + + +V + + ER+ Sbjct: 160 DIPSEPWNTGHDWILADKRPTAW--FLPSIRAANVMAASLRKAGKSVVVL--NRKTFERE 215 Query: 313 VIMREFRSGSSRVLITTDLLARGID--VQQV----------------SLVINYDLPTNRE 354 + ++ TD+ G + V++V + I L + Sbjct: 216 --YPTIKQKKPDFILATDIAEMGANLCVERVLDCRTAFKPVLVDEGRKVAIKGPLRISAS 273 Query: 355 NYIHRIGRGGR 365 + R GR GR Sbjct: 274 SAAQRRGRIGR 284 >2V6J-A nrPDB Length = 431 Score = 46.9 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 49/316 (15%), Positives = 102/316 (32%), Gaps = 80/316 (25%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G GKT + L + E K + ++LAPTR +A + + + G Sbjct: 12 GAGKTRR-VLPQLVR-EAVKKRLRTVILAPTRVVASETYEALR---------------GE 54 Query: 139 NVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMF--------VLDEAD----- 185 +R +Q E T + D + + K ++ ++DEA Sbjct: 55 PIRYMTPAVQSER------TGNEIVDFMCHSTFTMKLLQGVRVPNYNLYIMDEAHFLDPA 108 Query: 186 EMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEG 245 + +RG+ + + + + ++AT P P + EE + Sbjct: 109 SVAARGYIETRVSMG-----DAGAIFMTATPPGTTEAF------PPSNSPIIDEETRIP- 156 Query: 246 IRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGD 305 ++ + E + V F+++ ++ + + V ++ Sbjct: 157 ----------DKAWNSGYEWITEF--DGRTVWFVHSIKQGAEIGTCLQKAGKKVLYLNRK 204 Query: 306 MDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLV--------INYD--------L 349 + E + +S +ITTD+ G + + ++ I D + Sbjct: 205 TFESE----YPKCKSEKWDFVITTDISEMGANFKADRVIDPRKTIKPILLDGRVSMQGPI 260 Query: 350 PTNRENYIHRIGRGGR 365 + R GR GR Sbjct: 261 AITPASAAQRRGRIGR 276 >2WV9-A nrPDB Length = 673 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 44/312 (14%), Positives = 91/312 (29%), Gaps = 69/312 (22%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G GKT I++ + K + VLAPTR +A ++ + + G Sbjct: 251 GAGKTRRILPQIIK--DAIQKRLRTAVLAPTRVVAAEMAEALR------GLPVRYLTPAV 302 Query: 139 NVRAEVQKLQMEAPHIIVGTPG-RVFDMLNRRYLSPKYIKMFVLDEAD-----EMLSRGF 192 ++ H T R+ L + FV+DEA + +RG+ Sbjct: 303 QREHSGNEIVDVMCH---ATLTHRLMSPLRVPNYNL-----FVMDEAHFTDPASIAARGY 354 Query: 193 KDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYIN 252 + + ++AT P + Sbjct: 355 IAT-----RVEAGEAAAIFMTATPPGTSDPF-----------------PDTNSPVHDVSS 392 Query: 253 VEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERD 312 + + + + V F+ + + + + + + V ++ E Sbjct: 393 EIPDRAWSSGFEWITDYA--GKTVWFVASVKMSNEIAQCLQRAGKRVIQLNRKSYDTE-- 448 Query: 313 VIMREFRSGSSRVLITTDLLARGIDVQQVSLV-----------------INYDLPT--NR 353 + ++G +ITTD+ G + ++ + +P+ Sbjct: 449 --YPKCKNGDWDFVITTDISEMGANFGASRVIDCRKSVKPTILDEGEGRVILSVPSAITS 506 Query: 354 ENYIHRIGRGGR 365 + R GR GR Sbjct: 507 ASAAQRRGRVGR 518 >2V8O-A nrPDB Length = 444 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 44/312 (14%), Positives = 91/312 (29%), Gaps = 69/312 (22%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G GKT I++ + K + VLAPTR +A ++ + + G Sbjct: 22 GAGKTRRILPQIIK--DAIQKRLRTAVLAPTRVVAAEMAEALR------GLPVRYLTPAV 73 Query: 139 NVRAEVQKLQMEAPHIIVGTPG-RVFDMLNRRYLSPKYIKMFVLDEAD-----EMLSRGF 192 ++ H T R+ L + FV+DEA + +RG+ Sbjct: 74 QREHSGNEIVDVMCH---ATLTHRLMSPLRVPNYNL-----FVMDEAHFTDPASIAARGY 125 Query: 193 KDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYIN 252 + + ++AT P + Sbjct: 126 IAT-----RVEAGEAAAIFMTATPPGTSDPF-----------------PDTNSPVHDVSS 163 Query: 253 VEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERD 312 + + + + V F+ + + + + + + V ++ E Sbjct: 164 EIPDRAWSSGFEWITDYA--GKTVWFVASVKMSNEIAQCLQRAGKRVIQLNRKSYDTE-- 219 Query: 313 VIMREFRSGSSRVLITTDLLARGIDVQQVSLV-----------------INYDLPT--NR 353 + ++G +ITTD+ G + ++ + +P+ Sbjct: 220 --YPKCKNGDWDFVITTDISEMGANFGASRVIDCRKSVKPTILDEGEGRVILSVPSAITS 277 Query: 354 ENYIHRIGRGGR 365 + R GR GR Sbjct: 278 ASAAQRRGRVGR 289 >5OQJ-7 nrPDB Length = 843 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 35/234 (14%), Positives = 76/234 (32%), Gaps = 44/234 (18%) Query: 178 MFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVT------------K 225 +LDE + + F+ + I + L+AT+ + ++ Sbjct: 484 FIILDEVHVVPAAMFRRVVSTIAAHAK-----LGLTATLVREDDKIGDLNFLIGPKLYEA 538 Query: 226 KFM---RDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDL--------------YE 268 +M + V+ E+ +FY RE + L + Y Sbjct: 539 NWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQYH 598 Query: 269 TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFR-SGSSRVLI 327 + ++F + + KM ++G Q+ER I++ F+ + + Sbjct: 599 ERRGDKIIVFSDNVYALQEYALKMGKP-----FIYGSTPQQERMNILQNFQYNDQINTIF 653 Query: 328 TTDLLARGIDVQQVSLVI----NYDLPTNRENYIHRIGRGGRFGRKGVAINMVT 377 + + ID+ + + +I +Y + RI R R +G + Sbjct: 654 LSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFYS 707 >1RIF-A nrPDB Length = 282 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 25/154 (16%), Positives = 50/154 (32%), Gaps = 12/154 (7%) Query: 32 DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL 91 FD+ + G +P Q+ A+ + I + G++ ++L Sbjct: 94 KDFDEWLSKLEIYSGNKRI---EPHWYQKDAVFEGLVNRRRILNLPTSAGRSL--IQALL 148 Query: 92 QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEA 151 + L+ + L++ PT L Q+ + + A GG + + Sbjct: 149 ARYYLENYEGKILIIVPTTALTTQMADDFVDYRLFSHAMIKKIGGGASKDDKY----KND 204 Query: 152 PHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD 185 ++VGT V + M + DE Sbjct: 205 APVVVGTWQTVV---KQPKEWFSQFGMMMNDECH 235 >5WDX-A nrPDB Length = 649 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 44/265 (16%), Positives = 78/265 (29%), Gaps = 56/265 (21%) Query: 76 AQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACI 135 A +G+GK+ + + + LVL P+ + G Y+ + H Sbjct: 222 APTGSGKS------TKVPVAYAAQGYKVLVLNPS-------VAATLGFGAYL-SKAHGI- 266 Query: 136 GGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADE-----MLSR 190 + M I T G+ L + + + DE +L Sbjct: 267 --NPNIRTGVRTVMTGEAITYSTYGK---FLADGGCASGAYDIIICDECHAVDATSILGI 321 Query: 191 GFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFY 250 G + VL +AT P V D + + +E Sbjct: 322 GTVLD----QAETAGVRLTVLATATPPGSV----TTPHPDIEEVGLGREGE--------- 364 Query: 251 INVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKE 310 I L + + +IF ++++K D L + A + +D Sbjct: 365 IPFYGRAIPLSCI-------KGGRHLIFCHSKKKCDELAAALRGMGLNAVAYYRGLD--- 414 Query: 311 RDVIMREFRSGSSRVLITTDLLARG 335 I+ G V++ TD L G Sbjct: 415 -VSIIPA--QGDV-VVVATDALMTG 435 >3BXZ-A nrPDB Length = 471 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 43/292 (14%), Positives = 101/292 (34%), Gaps = 41/292 (14%) Query: 72 VIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASC 131 IA+ ++G GKT T + + +V LAQ+ + L +++G + Sbjct: 100 CIAEMRTGEGKTLTATLPA--YLNALTGKGVHVVTVNDY-LAQRDAENNRPLFEFLGLTV 156 Query: 132 HACIGGTNVRAEVQKLQMEAPHIIVGTPGRV-FDMLNRRYL------SPKYIKMFVLDEA 184 + G A+ + A I GT FD L + + ++DE Sbjct: 157 GINLPGMPAPAKREA---YAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEV 213 Query: 185 DEMLSRGFKDQIYDIFQKLNSNTQVV----------------LLSATMPSDVLEVTKKFM 228 D +L D+ ++ Q + ++ T ++ E + + Sbjct: 214 DSIL----IDEARTPL-IISGANQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYK 268 Query: 229 RDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTIT--QAVIFINTRRKVD 286 D + + + + + Y+ E K+ + + + T ++ + K + Sbjct: 269 LDTVVVPTNRPMIRKDLPDLVYMT---EAEKIQAIIEDIKERTAKGQPVLVGTISIEKSE 325 Query: 287 WLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDV 338 ++ ++ + ++ E ++ + + V I T++ RG D+ Sbjct: 326 LVSNELTKAGIKHNVLNAKFHANEAAIVAQA--GYPAAVTIATNMAGRGTDI 375 >5GN1-A nrPDB Length = 366 Score = 41.1 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 25/131 (19%), Positives = 53/131 (40%), Gaps = 7/131 (5%) Query: 259 KLDTLCDLYETLTITQ---AVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIM 315 K+D L L +T+ + + +IF + +D L + D+ + G +R +++ Sbjct: 186 KIDALKKLLKTIIVDKQEKVLIFSLFTQVLDILEMVLSTLDYKFLRLDGSTQVNDRQLLI 245 Query: 316 REFRSGS-SRVLI-TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVA- 372 +F + I +T GI++ + VI +D N + R R G+ Sbjct: 246 DKFYEDKDIPIFILSTKAGGFGINLVCANNVIIFDQSFNPHDDRQAADRAHRVGQTKEVN 305 Query: 373 -INMVTEEDKR 382 ++T++ Sbjct: 306 ITTLITKDSIE 316 >1Z6A-A nrPDB Length = 500 Score = 41.1 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 50/124 (40%), Gaps = 5/124 (4%) Query: 255 REEWKLDTLCDLYET--LTITQAVIFINTRRKVDWLTEKMHAR-DFTVSAMHGDMDQKER 311 R K+ ++ E + IF + + + V ++G++ +KER Sbjct: 322 RRSGKMIRTMEIIEEALDEGDKIAIFTQFVDMGKIIRNIIEKELNTEVPFLYGELSKKER 381 Query: 312 DVIMREFRSGSSR--VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRK 369 D I+ +F++ S ++++ GI++ + VI++D N R R G+ Sbjct: 382 DDIISKFQNNPSVKFIVLSVKAGGFGINLTSANRVIHFDRWWNPAVEDQATDRVYRIGQT 441 Query: 370 GVAI 373 I Sbjct: 442 RNVI 445 >1Z5Z-A nrPDB Length = 271 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 50/124 (40%), Gaps = 5/124 (4%) Query: 255 REEWKLDTLCDLYET--LTITQAVIFINTRRKVDWLTEKMHAR-DFTVSAMHGDMDQKER 311 R K+ ++ E + IF + + + V ++G++ +KER Sbjct: 93 RRSGKMIRTMEIIEEALDEGDKIAIFTQFVDMGKIIRNIIEKELNTEVPFLYGELSKKER 152 Query: 312 DVIMREFRSGSSR--VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRK 369 D I+ +F++ S ++++ GI++ + VI++D N R R G+ Sbjct: 153 DDIISKFQNNPSVKFIVLSVKAGGFGINLTSANRVIHFDRWWNPAVEDQATDRVYRIGQT 212 Query: 370 GVAI 373 I Sbjct: 213 RNVI 216 >1TF2-A nrPDB Length = 844 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 56/142 (39%), Gaps = 17/142 (11%) Query: 55 PSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRE-LA 113 P +Q + G IA+ ++G GKT T + + L+ + + + E LA Sbjct: 84 PFKVQLMGGVALHDGN--IAEMKTGEGKTLTSTLP----VYLNALTGKGVHVVTVNEYLA 137 Query: 114 QQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRV-FDMLN----- 167 + + + + +++G + + + + + A I T + FD L Sbjct: 138 SRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREA---YAADITYSTNNELGFDYLRDNMVL 194 Query: 168 -RRYLSPKYIKMFVLDEADEML 188 + + + + V+DE D +L Sbjct: 195 YKEQMVQRPLHFAVIDEVDSIL 216 Score = 38.8 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 26/181 (14%), Positives = 62/181 (34%), Gaps = 15/181 (8%) Query: 211 LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYET- 269 ++ T ++ E + + I + + + Y +E K + + Sbjct: 372 GMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEG---KFKAVAEDVAQR 428 Query: 270 -LTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328 +T ++ + +++ + + ++ ++E +I + G+ V I Sbjct: 429 YMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGA--VTIA 486 Query: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHR--------IGRGGRFGRKGVAINMVTEED 380 T++ RG D++ V H GR GR G G+ ++ ED Sbjct: 487 TNMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMED 546 Query: 381 K 381 + Sbjct: 547 E 547 >5EUL-A nrPDB Length = 836 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 56/142 (39%), Gaps = 17/142 (11%) Query: 55 PSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRE-LA 113 P +Q + G IA+ ++G GKT T + + L+ + + + E LA Sbjct: 81 PFKVQLMGGVALHDGN--IAEMKTGEGKTLTSTLP----VYLNALTGKGVHVVTVNEYLA 134 Query: 114 QQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRV-FDMLN----- 167 + + + + +++G + + + + + A I T + FD L Sbjct: 135 SRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREA---YAADITYSTNNELGFDYLRDNMVL 191 Query: 168 -RRYLSPKYIKMFVLDEADEML 188 + + + + V+DE D +L Sbjct: 192 YKEQMVQRPLHFAVIDEVDSIL 213 Score = 38.4 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 26/181 (14%), Positives = 62/181 (34%), Gaps = 15/181 (8%) Query: 211 LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYET- 269 ++ T ++ E + + I + + + Y +E K + + Sbjct: 369 GMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEG---KFKAVAEDVAQR 425 Query: 270 -LTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328 +T ++ + +++ + + ++ ++E +I + G+ V I Sbjct: 426 YMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGA--VTIA 483 Query: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHR--------IGRGGRFGRKGVAINMVTEED 380 T++ RG D++ V H GR GR G G+ ++ ED Sbjct: 484 TNMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMED 543 Query: 381 K 381 + Sbjct: 544 E 544 >4QQW-A nrPDB Length = 964 Score = 40.3 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 65/407 (15%), Positives = 122/407 (29%), Gaps = 114/407 (28%) Query: 72 VIAQAQSGTGKT-ATFAIS-ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGA 129 V+ A G GKT A + ++ +L + AL PT A Q+ + Y Sbjct: 321 VLITAPMGEGKTEAAYHVADLLGKATGRPGRFLAL---PTMATADQMHTRLKEYARYRVE 377 Query: 130 --------------------------------SCHACIGGTNVRAEVQKLQMEAPHII-- 155 + +G + A L ++ Sbjct: 378 NTDLPRSSTLALLHSMAWLNPDYAPADLPGVSKVLSNLGHRDPFAATDWLMGRKRGLLAP 437 Query: 156 --VGTPG-RVFDMLNRRYLSPKYI----KMFVLDEADEMLSRGFKDQIYDIFQKLNS-NT 207 VGT + +L ++ + + K+ V+DEA + + + + + L + + Sbjct: 438 WAVGTIDQALMAVLRAKHNALRLFGLAGKVVVVDEAHAV-DPYMQVLLEQLLRWLGTLDV 496 Query: 208 QVVLLSATMPSDVL----------------------------------------EVTKKF 227 VVLLSAT+ + +VT+ Sbjct: 497 PVVLLSATLHHSIANSLVKAYLEGARGRRWNRSEPQPVSEVSYPGWLHVDARIGKVTRSS 556 Query: 228 MRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL--TITQAVIFINTRRKV 285 DP+ I + + + E + L L A I T + Sbjct: 557 DVDPLPIATTPRKPLEVRLVDVPVK-EGALNRSTVLAKELTPLVKQGGCAAIICTTVAEA 615 Query: 286 DWLTEKMHARDFTVSA-------MHGDMDQKERDV----IMREF---------RSGSSRV 325 + + + T+ +H ++R I+ F R V Sbjct: 616 QGVYDLLSQWFATLGEDAPDLYLLHSRFPNRQRTEITATIVDLFGKEGAQSGRRPTRGAV 675 Query: 326 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVA 372 L+ T ++ + +D+ V L+I+ P + + R GR R G+ Sbjct: 676 LVATQVVEQSLDL-DVDLMISDLAPVSLL--LQRAGRCWRHEHLGII 719 >2FZ4-A nrPDB Length = 237 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 24/161 (14%), Positives = 59/161 (36%), Gaps = 27/161 (16%) Query: 59 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 118 Q++A+ + +G+GKT A++ + ++ L++ PT LA+Q ++ Sbjct: 98 QEKALERWLVDKRGCIVLPTGSGKTHV-AMAAINELSTP-----TLIVVPTLALAEQWKE 151 Query: 119 VVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKM 178 + G+ G + ++ ++ N L +++ + Sbjct: 152 RLGIFGEEY---VGEFSGRIKELKPLTVSTYDSAYV------------NAEKLGNRFM-L 195 Query: 179 FVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSD 219 + DE + + I Q ++ + L+AT + Sbjct: 196 LIFDEVHHLP----AESYVQIAQ-MSIAPFRLGLTATFERE 231 >6FWS-A nrPDB Length = 716 Score = 38.4 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 10/67 (14%) Query: 55 PSAIQQRAI------LPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAP 108 P A Q++ I L +G + +A +G GKT ++ I + + K LV++ Sbjct: 27 PRAPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQK---TLVVS- 82 Query: 109 TRELAQQ 115 T +A Q Sbjct: 83 TANVALQ 89 >3LLM-A nrPDB Length = 235 Score = 37.6 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 46/219 (21%), Positives = 83/219 (37%), Gaps = 18/219 (8%) Query: 18 EPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQ 77 PE + NE++ + + +++L+ +K + + + VI + Sbjct: 28 TPEQISMDLKNELMYQLEQDHDLQAILQERELLPVKKF---ESEILEAISQNSVVIIRGA 84 Query: 78 SGTGKTATFAISILQQIELDLKATQA--LVLAPTRELAQQIQK-VVMALGDYMGASCHAC 134 +G GKT IL + +A + +V P R A + + V G+ G SC Sbjct: 85 TGCGKTTQVPQFILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSC--- 141 Query: 135 IGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD-EMLSRGFK 193 G +VR E L I+ T G + L + I ++DE ++ F Sbjct: 142 --GYSVRFESI-LPRPHASIMFCTVGVLLRKLEAGI---RGISHVIVDEIHERDINTDFL 195 Query: 194 DQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPI 232 + + ++VL+SAT+ D + F PI Sbjct: 196 LVVLRDVVQAYPEVRIVLMSATI--DTSMFCEYFFNCPI 232 >6EG3-A nrPDB Length = 621 Score = 37.3 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 38/111 (34%), Gaps = 8/111 (7%) Query: 79 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 138 G GKT I +E L++ P L + + GT Sbjct: 418 GLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTL----SNWTYEFDKWAPSVVKISYKGT 473 Query: 139 N--VRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEM 187 R+ V +L+ ++++ T + ++ L+ K ++DE M Sbjct: 474 PAMRRSLVPQLRSGKFNVLLTTYEYIIK--DKHILAKIRWKYMIVDEGHRM 522 >5H8W-A nrPDB Length = 597 Score = 37.3 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 26/65 (40%), Gaps = 2/65 (3%) Query: 76 AQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACI 135 + +G+GKT S LQ + + L L T +Q+ K + +L M Sbjct: 11 SPTGSGKTIMALKSALQ--YSSERKLKVLYLVRTNSQEEQVIKELRSLSSTMKIRAIPMQ 68 Query: 136 GGTNV 140 G N+ Sbjct: 69 GRVNM 73 >1Z3I-X nrPDB Length = 644 Score = 36.9 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 49/116 (42%), Gaps = 3/116 (2%) Query: 260 LDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFR 319 LD + + T T + V+ N + +D + R + + G M K+R I+ F Sbjct: 404 LDYILAMTRTTTSDKVVLVSNYTQTLDLFEKLCRNRRYLYVRLDGTMSIKKRAKIVERFN 463 Query: 320 SGSSR---VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVA 372 + SS ++++ G+++ + ++ +D N N + R R G+K Sbjct: 464 NPSSPEFIFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTC 519 >1NLZ-A nrPDB Length = 330 Score = 35.3 bits (80), Expect = 0.045, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 37/92 (40%), Gaps = 8/92 (8%) Query: 48 YAYGFEKPSAIQQRAILPCIKG----YDVIAQAQSGTGKTATFAISILQQIELDLKATQA 103 GF +++AI G +VI +G+GKT T+ SI++ I K + Sbjct: 146 EEQGFYNLLDNKEQAISAIKDGIAIGKNVIVCGGTGSGKT-TYIKSIMEFI---PKEERI 201 Query: 104 LVLAPTRELAQQIQKVVMALGDYMGASCHACI 135 + + T E+ + K L + C+ Sbjct: 202 ISIEDTEEIVFKHHKNYTQLFFGGNITSADCL 233 >5K9T-A nrPDB Length = 578 Score = 35.3 bits (80), Expect = 0.046, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 46/124 (37%), Gaps = 13/124 (10%) Query: 72 VIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASC 131 IA+ ++G GKT T + + +V LAQ+ + L +++G + Sbjct: 86 CIAEMRTGEGKTLTATLPA--YLNALTGKGVHVVTVNDY-LAQRDAENNRPLFEFLGLTV 142 Query: 132 HACIGGTNVRAEVQKLQMEAPHIIVGTPGRV-FDMLNRRYL------SPKYIKMFVLDEA 184 + G A+ + A I GT FD L + + ++DE Sbjct: 143 GINLPGMPAPAKREA---YAADITYGTNNEYGFDYLRDNMAFSPAARVQRKLHYALVDEV 199 Query: 185 DEML 188 D +L Sbjct: 200 DSIL 203 >3A2B-A nrPDB Length = 398 Score = 35.3 bits (80), Expect = 0.051, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 41/111 (36%), Gaps = 12/111 (10%) Query: 191 GFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFY 250 GF D+ L N + V+ SA+M + T K + +++ E +E Sbjct: 250 GFVAGDADVIDFLKHNARSVMFSASMTPASVASTLKALE-----IIQNEPEHIEK----- 299 Query: 251 INVEREEWKLDTLCDLYETLTITQAV--IFINTRRKVDWLTEKMHARDFTV 299 + + K L ++ + IFI + K W+T+ + V Sbjct: 300 LWKNTDYAKAQLLDHGFDLGATESPILPIFIRSNEKTFWVTKMLQDDGVFV 350 >2FSI-A nrPDB Length = 853 Score = 34.6 bits (78), Expect = 0.072, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 46/124 (37%), Gaps = 13/124 (10%) Query: 72 VIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASC 131 IA+ ++G GKT T + + +V LAQ+ + L +++G + Sbjct: 90 CIAEMRTGEGKTLTATLPA--YLNALTGKGVHVVTVNDY-LAQRDAENNRPLFEFLGLTV 146 Query: 132 HACIGGTNVRAEVQKLQMEAPHIIVGTPGRV-FDMLNRRYL------SPKYIKMFVLDEA 184 + G A+ + A I GT FD L + + ++DE Sbjct: 147 GINLPGMPAPAKREA---YAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEV 203 Query: 185 DEML 188 D +L Sbjct: 204 DSIL 207 >1NL3-A nrPDB Length = 922 Score = 34.6 bits (78), Expect = 0.090, Method: Composition-based stats. Identities = 24/143 (16%), Positives = 46/143 (32%), Gaps = 15/143 (10%) Query: 53 EKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTREL 112 ++P +Q G +A+ ++G GKT T + + +V L Sbjct: 110 QRPFDVQVMGAAALHLGN--VAEMKTGEGKTLTCVLPA--YLNALAGNGVHIVTVNDY-L 164 Query: 113 AQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRV-FDMLNRRYL 171 A++ + + + ++G + I GT FD L Sbjct: 165 AKRDSEWMGRVHRFLGLQVGVILATMTPDERRVA---YNADITYGTNNEFGFDYLRDNMA 221 Query: 172 -SPKYI-----KMFVLDEADEML 188 S + ++DE D +L Sbjct: 222 HSLDDLVQRGHHYAIVDEVDSIL 244 Score = 34.2 bits (77), Expect = 0.099, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 45/115 (39%), Gaps = 6/115 (5%) Query: 228 MRDPIRILVKKEELTLEGIR--QFYINVEREEWKLDTLCDLYETL--TITQAVIFINTRR 283 + + ++ V + IR Q + + EE K + D +I + Sbjct: 412 LHEIYKLGVVSIPTNMPMIREDQSDLIYKTEEAKYIAVVDDVAERYAKGQPVLIGTTSVE 471 Query: 284 KVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDV 338 + ++L+ + R + ++ ++E +I R G V + T++ RG D+ Sbjct: 472 RSEYLSRQFTKRRIPHNVLNAKYHEQEATIIAVAGRRG--GVTVATNMAGRGTDI 524 >5FL3-A nrPDB Length = 368 Score = 33.4 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 42/243 (17%), Positives = 81/243 (33%), Gaps = 48/243 (19%) Query: 27 WNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGK--TA 84 +E++ SF+ + L ++ + A +R + ++ +G+GK T Sbjct: 108 VSEVIPSFEALGLPREVMESLAAK---------ERGL--------ILVTGPTGSGKSTTL 150 Query: 85 TFA------------ISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCH 132 I+I IE K ++LV+ RE+ L + Sbjct: 151 AALIDHINLHYAKNIITIEDPIEFLHKHKKSLVVQ--REVGLDTDSFYTGLKYALRQDPD 208 Query: 133 ACIGGTNVRAEVQK---LQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLS 189 + G E + + + H+++ T L+ + I F L E + Sbjct: 209 VIMVGEMRDRETVEAALMAAQTGHLVLST----LHTLDAWRTINRIIDFFPLHE-HRQVR 263 Query: 190 RGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQF 249 + + I Q +L A VL + +R L+K EE T I++ Sbjct: 264 VLLAESLLGILS------QRLLPKADGQGRVLALEILIATPYVRELLKDEEKT-PQIKEA 316 Query: 250 YIN 252 + Sbjct: 317 MME 319 >1EJE-A nrPDB Length = 192 Score = 33.0 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 26/78 (33%), Gaps = 14/78 (17%) Query: 183 EADEMLSRGFKDQIYDIFQKLNSNTQVVL--------------LSATMPSDVLEVTKKFM 228 +A M+S F+D + ++ + V+ S TMP + F Sbjct: 3 QAAHMMSMDFEDFPVESAHRILTPRPTVMVTTVDEEGNINAAPFSFTMPVSIDPPVVAFA 62 Query: 229 RDPIRILVKKEELTLEGI 246 P + E T E + Sbjct: 63 SAPDHHTARNIESTHEFV 80 >4B3F-X nrPDB Length = 646 Score = 33.0 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 4/52 (7%) Query: 59 QQRAILPCIKGYDV-IAQAQSGTGKTATFAISILQQIELDLKATQALVLAPT 109 Q+ A+L + ++ I GTGKT T ILQ ++ + + L AP+ Sbjct: 194 QKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVK---QGLKVLCCAPS 242 >2V1U-A nrPDB Length = 387 Score = 31.1 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 32/149 (21%), Positives = 60/149 (40%), Gaps = 30/149 (20%) Query: 60 QRAILPCIKGY---DVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQI 116 + P ++G + + +GTGKTA + +L+++E + LV P A+ Sbjct: 32 AEVLAPALRGEKPSNALLYGLTGTGKTAVARL-VLRRLEARASSLGVLV-KPIYVNARHR 89 Query: 117 Q---KVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSP 173 + +V A+ + +G G +V ++L +R Sbjct: 90 ETPYRVASAIAEAVGVRVP--FTGLSVGEVYERLV-------------------KRLSRL 128 Query: 174 KYIKMFVLDEADEMLSR-GFKDQIYDIFQ 201 + I + VLDE D + R G +D +Y I + Sbjct: 129 RGIYIIVLDEIDFLPKRPGGQDLLYRITR 157 >4ZCF-C nrPDB Length = 970 Score = 31.1 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 37/108 (34%), Gaps = 3/108 (2%) Query: 74 AQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHA 133 ++GTGKT T+ +I + + +++ PT + + D + Sbjct: 82 VSMETGTGKTYTYIKTIFD-LNKSFGINKFIIIVPTLSIKAGTVNFLK--SDALKEHFRD 138 Query: 134 CIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVL 181 V+ + + P + D + + KYI + V+ Sbjct: 139 DYKRELRTYVVESQKNAGKNTKSYMPQAIHDFVEASNFNKKYIHVLVI 186 >1UB3-A nrPDB Length = 220 Score = 31.1 bits (69), Expect = 0.95, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 41/102 (40%), Gaps = 4/102 (3%) Query: 40 SESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFA--ISILQQIELD 97 +++L+ I G+ P I + A G D + + +G G +++L ++ Sbjct: 117 PQAVLKVILETGYFSPEEIARLAEAAIRGGADFLKTS-TGFGPRGASLEDVALLVRVAQG 175 Query: 98 LKATQALVLAPTRELAQQIQK-VVMALGDYMGASCHACIGGT 138 +A RE A ++ K LG G + A GGT Sbjct: 176 RAQVKAAGGIRDRETALRMLKAGASRLGTSSGVALVAGEGGT 217 >3CRV-A nrPDB Length = 551 Score = 30.7 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 49/342 (14%), Positives = 108/342 (31%), Gaps = 100/342 (29%) Query: 54 KPSAIQQRAILPCIKG--YDVIAQ--AQSGTGKTATFAISILQQIELDLKATQALVLAPT 109 K Q++ I+G + + A +G+GKT S+L +E+ + L + T Sbjct: 3 KLRDWQEKLKDKVIEGLRNNFLVALNAPTGSGKTL---FSLLVSLEVK---PKVLFVVRT 56 Query: 110 RELAQQIQKVVMALGDYMGASCHACIGG------TNVRAEVQKLQMEAPH-----IIVGT 158 I + + + + + +G AE + + + + V T Sbjct: 57 HNEFYPIYRDLTKIREKRNITFSFLVGKPSSCLYAEKGAESEDIPCKYCELKGSIVEVKT 116 Query: 159 ---PGRVFDMLNRRYLSPKYIK-------------------------------------M 178 P + L + L K+ M Sbjct: 117 DDSPLSLVKKLKKDGLQDKFCPYYSLLNSLYKADVIALTYPYFFIDRYREFIDIDLREYM 176 Query: 179 FVLDEADEM-------------------LSRGFKDQIYDIF-QKLNSNTQVVLLSATMPS 218 V+DEA + + + ++ I + LN +VVL P Sbjct: 177 IVIDEAHNLDKVNELEERSLSEITIQMAIKQSKSEESRRILSKLLNQLREVVL-----PD 231 Query: 219 D----VLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQ 274 + V V K + + E++ + ++Q + + + ++ + L+I Sbjct: 232 EKYIKVENVPKLSKEELEILADDYEDIRKDSLKQGKV----NKIHIGSILRFFSLLSIGS 287 Query: 275 AVIFINTRRKV------DWLTEKMHARDFTVSAMHGDMDQKE 310 + F ++R V + ++ + ++ M G + +E Sbjct: 288 FIPFSYSKRLVIKNPEISYYLNLLNDNELSIILMSGTLPPRE 329 >1SXJ-C nrPDB Length = 340 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 20/45 (44%), Gaps = 3/45 (6%) Query: 143 EVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEM 187 E+ ++ ++ D + R + K K+ +LDEAD M Sbjct: 81 ELNASDDRGIDVV---RNQIKDFASTRQIFSKGFKLIILDEADAM 122 >5O6D-A nrPDB Length = 545 Score = 30.3 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 54/153 (35%), Gaps = 24/153 (15%) Query: 56 SAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQ 115 S Q+ I G+++ +GTGK+ +L+++ LK RE Sbjct: 3 SKEQESIIKLAENGHNIFYTGSAGTGKSI-----LLREMIKVLKGIYG------RENVAV 51 Query: 116 IQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKY 175 +A + G + H+ G + + KL + + + Sbjct: 52 TASTGLAACNIGGITIHSFAGIGLGKGDADKLYKK------------VRRSRKHLRRWEN 99 Query: 176 IKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQ 208 I V+DE ML D++ I +K+ N Q Sbjct: 100 IGALVVDEI-SMLDAELLDKLDFIARKIRKNHQ 131 >4LRY-C nrPDB Length = 318 Score = 29.5 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 17/34 (50%) Query: 170 YLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKL 203 Y++P+ +F+LDE +LSR Q L Sbjct: 67 YMAPRECALFILDETACILSRNGDPQTLQQLSAL 100 >4HZU-A nrPDB Length = 279 Score = 29.2 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 27/159 (16%), Positives = 59/159 (37%), Gaps = 23/159 (14%) Query: 78 SGTGK-TATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGD-----YMGASC 131 +G+GK T ++ L + L P E Q+++ + + ++GA+ Sbjct: 42 NGSGKSTLAKSLDGLLPFTQGSVTVGGITLTP--ETVWQVREQIGMIFQNPDNQFVGATV 99 Query: 132 --HACIG----GTNVRAEVQKLQMEAPHIIVGT-----PGRVFDMLNRRYLSPKYI---- 176 G + V ++Q + + + P + +R + Sbjct: 100 EDDVAFGLENRQISRDEMVPRVQAALAQVGMTSFAQREPSSLSGGQKQRVALAGIVAIAP 159 Query: 177 KMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSAT 215 K+ +LDEA ML + ++ I ++L + ++S T Sbjct: 160 KILILDEATSMLDPQGRIEMLAIVRQLRQQQNLTVISIT 198 >4XRF-A nrPDB Length = 142 Score = 29.2 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 263 LCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGS 322 L + Y + VI T++ + E M AR+ ++ ++ +ER+ ++R F Sbjct: 76 LVERYHDKDDRRVVIIELTKKGKARVEEAMTARNEHIAKYFSHLELQEREDLLRLF-EKL 134 Query: 323 SRVLITT 329 ++ T Sbjct: 135 ETIICGT 141 >4B4H-A nrPDB Length = 420 Score = 29.2 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 26/63 (41%), Gaps = 6/63 (9%) Query: 17 MEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQA 76 ++ G IE N + S M L + L + G P IQ ++ + G D A A Sbjct: 40 LDRIGAIEGNDSPTTGS---MGLRDHLEEAVRQSG-GDPLTIQ--VVIYNLPGRDCAALA 93 Query: 77 QSG 79 +G Sbjct: 94 SNG 96 >4ZWB-A nrPDB Length = 518 Score = 29.2 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 23/144 (15%), Positives = 48/144 (33%), Gaps = 21/144 (14%) Query: 217 PSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAV 276 ++ + F P + E R IN + EE L L+ T ++Q + Sbjct: 202 SEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDI 261 Query: 277 IFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRV-LITTDLLARG 335 ++M M Q+++ ++ FR S R +I + +L Sbjct: 262 -------------QEMKDES-------ARMSQEKQVTVLELFRVSSYRQPIIISIVLQLS 301 Query: 336 IDVQQVSLVINYDLPTNRENYIHR 359 + ++ V Y ++ + Sbjct: 302 QQLSGINAVFYYSTGIFKDAGVQE 325 >6D00-1 nrPDB Length = 883 Score = 28.8 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 24/185 (12%), Positives = 55/185 (29%), Gaps = 31/185 (16%) Query: 59 QQRAILPC----------IKGYD-----VIAQAQSGTGKTATFAISILQQIELDLKATQA 103 Q AI ++ + + +G GKT + + A Sbjct: 575 QDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLC----VKELAAFLFNDPGA 630 Query: 104 LVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVF 163 +V + + + G + ++ + P+ +V +F Sbjct: 631 IV-------RIDMSEYMEKHAVSRLVGAPPGYIGHDEGGQLTEAVRRRPYTVV-----LF 678 Query: 164 DMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEV 223 D + + + + + +LD+ S+G + + + SN L V + Sbjct: 679 DEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLGADLFELDEGDKVSQA 738 Query: 224 TKKFM 228 TK + Sbjct: 739 TKNAV 743 >3J7Y-f nrPDB Length = 211 Score = 28.8 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 26/56 (46%) Query: 183 EADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK 238 E ++ +G K + + Q+ LSAT LE+ + + + +R+ VK+ Sbjct: 133 EVLQLQDQGSKMLLDSVLTTHERVVQISGLSATFAEIFLEIIQSSLPEGVRLSVKE 188 >2Q6T-A nrPDB Length = 444 Score = 28.8 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 19/52 (36%) Query: 108 PTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTP 159 P REL + + + AL G G + + L + +II P Sbjct: 158 PMRELVHETFEHIEALFQNKGEVAGVRTGFKELDQLIGTLGPGSLNIIAARP 209 >4H1G-A nrPDB Length = 715 Score = 28.8 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 37/97 (38%), Gaps = 16/97 (16%) Query: 14 PDGMEPEGVIESNWNEIVDS-FDDMNLSESLLRGIYAYG------FEKPSAIQQRAILPC 66 P + E E +++ F ++ L I+ FE+ S + I Sbjct: 406 PQDINDESKQELVITRNINNNFSNLRF---LFDKIFEREQSNDLVFEELS----QLIQCS 458 Query: 67 IKGYDVIAQA--QSGTGKTATFAISILQQIELDLKAT 101 + G +V A Q+G+GKT T + I L LK Sbjct: 459 LDGTNVCVFAYGQTGSGKTFTMSHPTNGMIPLSLKKI 495 >6FES-A nrPDB Length = 367 Score = 28.8 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 47/117 (40%), Gaps = 21/117 (17%) Query: 161 RVFDMLNRRYLSPKY-IKMFV-----LDEADEML---------SRGFKDQIYDIFQKLNS 205 R+ D++ L+ + IKM V L EA +L F + IY + + Sbjct: 253 RLLDLMVDPNLNEEQYIKMVVDALKILIEAVNVLIKMVEKNPEDMEFWNLIYRLVHVMKE 312 Query: 206 NTQVVLLS--ATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKL 260 T+ + S A + ++ + K + I+I ++ +++ V RE K+ Sbjct: 313 VTETMGFSSVAKVLHTIMNLVDKMLNSEIKIT----SDLIDKVKKKLDMVTRELDKM 365 >2Y4N-A nrPDB Length = 437 Score = 28.8 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 20/42 (47%), Gaps = 3/42 (7%) Query: 135 IGGTNVRAEVQKLQMEAPHIIVGTPG---RVFDMLNRRYLSP 173 GG +VQ +Q P II+ TP + D + R+ L P Sbjct: 166 FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEIERQGLDP 207 >6F5D-G nrPDB Length = 304 Score = 28.8 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 15/138 (10%), Positives = 51/138 (36%), Gaps = 6/138 (4%) Query: 246 IRQFYINVEREEWKLDTLCDLYETLTITQAVIFI--NTRRKVDWLTEKMHARDFTVSAMH 303 + + V ++ + + + + + + + ++ + + + L + + + + Sbjct: 142 VIENAYEVSKDADRYQVIFNRFVSAGVQRNAVYNIPSYEKWKEDLADAASSDNQKNRYLF 201 Query: 304 GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIG-- 361 + Q E + ++R+F + + + + + Q LV TN + R Sbjct: 202 ANALQNEEEQLIRDFFDFHAALAVLNAVGENELSEQAARLVAVEGQLTNISSLQQRTSSL 261 Query: 362 --RGGRFGRKGVAINMVT 377 + +FG I +++ Sbjct: 262 YNKTRQFGITAALIEILS 279 >3ACB-A nrPDB Length = 181 Score = 28.4 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 4/71 (5%) Query: 67 IKGYDVIAQAQ-SGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGD 125 I G DVI TG T ++ + L+ + AL+ P+R +Q++ + LG Sbjct: 93 IHGRDVIVVEDIVDTGLTLSYLLDYLEARKPASVRVAALLSKPSR---RQVEVPIHYLGF 149 Query: 126 YMGASCHACIG 136 + + G Sbjct: 150 EIEDAYVYGYG 160 >2JGA-A nrPDB Length = 292 Score = 28.4 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 24/140 (17%), Positives = 54/140 (38%), Gaps = 10/140 (7%) Query: 164 DMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEV 223 +L ++ L +K V E+D ML G+++ + Q + V + SA + + EV Sbjct: 114 GLLVQQALPKAKLKEIVA-ESDVMLKEGYENFFDKLQQH---SIPVFIFSAGIGDVLEEV 169 Query: 224 TKKF-MRDPIRILVKK-----EELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVI 277 ++ + P +V E L+G + I+V + + + L +I Sbjct: 170 IRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALRNTEYFNQLKDNSNII 229 Query: 278 FINTRRKVDWLTEKMHARDF 297 + + + + + + Sbjct: 230 LLGDSQGDLRMADGVANVEH 249 >4U00-A nrPDB Length = 244 Score = 28.4 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 31/190 (16%), Positives = 72/190 (37%), Gaps = 28/190 (14%) Query: 68 KGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYM 127 G ++ SG+GK+ I + ++E D + + +V L+ + + + + Sbjct: 29 PGEKLVIIGPSGSGKST--LIRTINRLE-DFQEGEVVVDG----LSVKDDRALREI---- 77 Query: 128 GASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLS--PKYIKMF-VLDEA 184 N+ + L+ + P RV + + ++ +LD+A Sbjct: 78 RREVGMVFQQFNLFPHMTVLEN-----VTLAPMRVRRWPREKAEKKALELLERVGILDQA 132 Query: 185 DEMLSR--GFKDQIYDIFQKLNSNTQVVLL----SATMPS---DVLEVTKKFMRDPIRIL 235 + ++ G + Q I + L +++L SA P +VL+V + + + ++ Sbjct: 133 RKYPAQLSGGQQQRVAIARALAMEPKIMLFDEPTSALDPEMVGEVLDVMRDLAQGGMTMV 192 Query: 236 VKKEELTLEG 245 V E+ Sbjct: 193 VVTHEMGFAR 202 >1Z7N-E nrPDB Length = 208 Score = 28.4 bits (62), Expect = 6.0, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 26/70 (37%), Gaps = 3/70 (4%) Query: 116 IQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKY 175 IQK V L + + N+ E+Q + II G P V L + + Sbjct: 11 IQKQVTKLLENADYDVEPIL---NLGRELQIKTKDDLQIIFGKPNDVITFLEHGIVDIGF 67 Query: 176 IKMFVLDEAD 185 + LDE D Sbjct: 68 VGKDTLDEND 77 >1D5A-A nrPDB Length = 733 Score = 28.0 bits (61), Expect = 8.4, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 35/82 (42%), Gaps = 6/82 (7%) Query: 164 DMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMP----SD 219 R + K K V+DE D++ +RG + + + ++ TQ +L A + + Sbjct: 581 GFYRRGFFVTKK-KYAVIDEEDKITTRGLE-IVRRDWSEIAKETQARVLEAILKHGDVEE 638 Query: 220 VLEVTKKFMRDPIRILVKKEEL 241 + + K+ R V E+L Sbjct: 639 AVRIVKEVTEKLSRHEVPPEKL 660 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.143 0.379 Lambda K H 0.267 0.0436 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,892,475 Number of Sequences: 36641 Number of extensions: 599274 Number of successful extensions: 2659 Number of sequences better than 10.0: 180 Number of HSP's better than 10.0 without gapping: 200 Number of HSP's successfully gapped in prelim test: 84 Number of HSP's that attempted gapping in prelim test: 1938 Number of HSP's gapped (non-prelim): 371 length of query: 406 length of database: 10,336,785 effective HSP length: 99 effective length of query: 307 effective length of database: 6,709,326 effective search space: 2059763082 effective search space used: 2059763082 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.6 bits)