BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P57761 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5IY4-A nrPDB 530 e-151 4CS5-A nrPDB 421 e-118 4HK1-A nrPDB 392 e-110 6O09-C nrPDB 372 e-104 2ZVW-A nrPDB 371 e-103 5TUP-A nrPDB 300 5e-82 5CFK-A nrPDB 239 9e-64 6J0J-A nrPDB 223 5e-59 5ZUT-A nrPDB 201 2e-52 3K4X-A nrPDB 197 3e-51 4L60-A nrPDB 191 2e-49 3P91-A nrPDB 167 5e-42 3L0X-A nrPDB 133 7e-32 5A6D-A nrPDB 93 9e-20 5DA7-A nrPDB 91 5e-19 1ISQ-A nrPDB 90 9e-19 1UD9-A nrPDB 82 2e-16 1RXZ-A nrPDB 82 3e-16 2IX2-C nrPDB 80 8e-16 3IFV-A nrPDB 73 1e-13 2IO4-B nrPDB 71 4e-13 3AIZ-C nrPDB 70 8e-13 3PGE-A nrPDB 69 2e-12 3L0X-B nrPDB 69 2e-12 3LX2-A nrPDB 69 2e-12 6AIG-A nrPDB 67 9e-12 3L10-B nrPDB 63 1e-10 3AIZ-A nrPDB 56 2e-08 2HII-A nrPDB 33 0.12 6HUM-J nrPDB 29 2.5 4HJV-A nrPDB 28 2.8 6D46-A nrPDB 27 6.8 2AW5-A nrPDB 27 8.1 >5IY4-A nrPDB Length = 270 Score = 530 bits (1365), Expect = e-151, Method: Compositional matrix adjust. Identities = 257/261 (98%), Positives = 258/261 (98%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 MFEARLVQGSILKKVLEALKDLINEACWDISS GVNLQSMDSSHVSLVQLTLRSEGFDTY Sbjct: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD Sbjct: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI Sbjct: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLS TVTLSMS DVPLVVEYK Sbjct: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYK 240 Query: 241 ISDMGHLKYYLAPKIEDEEGS 261 I+DMGHLKYYLAPKIEDEEGS Sbjct: 241 IADMGHLKYYLAPKIEDEEGS 261 >4CS5-A nrPDB Length = 260 Score = 421 bits (1081), Expect = e-118, Method: Compositional matrix adjust. Identities = 191/259 (73%), Positives = 230/259 (88%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 MFEARLVQGS+LKKVLEA+KDL+NEA WD + G+ LQ+MD+SHVSLV L LR++GFD Y Sbjct: 1 MFEARLVQGSLLKKVLEAIKDLLNEASWDCADSGIQLQAMDNSHVSLVSLNLRAKGFDKY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRNL MG+NLTSMSKILKCA N+DIIT++A+DNADT+ +FE+PNQEKVSDYEMKLM+ Sbjct: 61 RCDRNLIMGMNLTSMSKILKCAANDDIITMKAQDNADTVTFMFESPNQEKVSDYEMKLMN 120 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 LD E LGIPE +Y+CV+K+PSGEFARICRDLS G+++VI+C K+GVKFSA+G++G NI Sbjct: 121 LDQEHLGIPETDYACVIKLPSGEFARICRDLSQFGESIVIACTKEGVKFSAAGDIGTANI 180 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 KL+QTS+VDKEEEAV IEM EPV LTFA RYLN FTKATPLSP V+LSMS DVPLVVEY Sbjct: 181 KLAQTSSVDKEEEAVVIEMQEPVTLTFACRYLNMFTKATPLSPQVSLSMSPDVPLVVEYA 240 Query: 241 ISDMGHLKYYLAPKIEDEE 259 I ++GH++Y+LAPKIEDE+ Sbjct: 241 IGEIGHIRYFLAPKIEDED 259 >4HK1-A nrPDB Length = 263 Score = 392 bits (1008), Expect = e-110, Method: Compositional matrix adjust. Identities = 182/259 (70%), Positives = 220/259 (84%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 MFEARL Q +ILKK+L+A+KDL+NEA +D S G+ LQ+MD+SHVSLV LTLRS+GFD + Sbjct: 4 MFEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKF 63 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRNL+MG+NL SM+KILKCA NED +T++A+DNADT+ ++FE+ NQEKVSDYEMKLM+ Sbjct: 64 RCDRNLSMGMNLGSMAKILKCANNEDNVTMKAQDNADTVTIMFESANQEKVSDYEMKLMN 123 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 LD E LGIPE ++SCVV+MP+ EFARICRDL+ ++VVI C K+GVKFSASG++G NI Sbjct: 124 LDQEHLGIPETDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANI 183 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 KL+QT +VDKEEEAV IEM EPV LTFA RYLN FTKATPLS V LSM DVPLVVEY Sbjct: 184 KLAQTGSVDKEEEAVIIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYA 243 Query: 241 ISDMGHLKYYLAPKIEDEE 259 I D+GH++YYLAPKIED E Sbjct: 244 IKDLGHIRYYLAPKIEDNE 262 >6O09-C nrPDB Length = 312 Score = 372 bits (955), Expect = e-104, Method: Compositional matrix adjust. Identities = 168/259 (64%), Positives = 221/259 (85%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M E RLVQGS+LKKVLE++KDL+N+A +D SS G +LQ+MDSSHV+LV L LRSEGF+ Y Sbjct: 50 MLELRLVQGSLLKKVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSEGFEHY 109 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRNL+MG+NL +MSK+LKCAGN+DIIT++A+D DT+ +FE+P Q+K++D+EMKLMD Sbjct: 110 RCDRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMD 169 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D E LGIP+ EY +V+MPS EF+RIC+DLS IGD VVIS K+GVKFS +G++G NI Sbjct: 170 IDSEHLGIPDAEYHSIVRMPSNEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANI 229 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 L Q + VDK E+A+ IEM EPV L+FALRY+N FTKATPLS TVT+S+S+++P+VVEYK Sbjct: 230 VLRQNTTVDKPEDAIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYK 289 Query: 241 ISDMGHLKYYLAPKIEDEE 259 +++MG+++YYLAPKIE+EE Sbjct: 290 VAEMGYIRYYLAPKIEEEE 308 >2ZVW-A nrPDB Length = 275 Score = 371 bits (953), Expect = e-103, Method: Compositional matrix adjust. Identities = 167/255 (65%), Positives = 220/255 (86%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M E RLVQGS+LKKVLEA+KDL+N+A +D S+ G +LQ+MDSSHV+LV L LRSEGF+ Y Sbjct: 21 MLELRLVQGSLLKKVLEAVKDLVNDANFDCSTTGFSLQAMDSSHVALVSLLLRSEGFEHY 80 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRNL+MG+NL +MSK+LKCAGN+DIIT++A+D +DT+ +FE+P Q+K++D+EMKLMD Sbjct: 81 RCDRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGSDTVTFMFESPTQDKIADFEMKLMD 140 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D E LGIP+ EY +V+MPSGEF+RIC+DLS IGD VVIS K+GVKFS +G++G NI Sbjct: 141 IDSEHLGIPDAEYHSIVRMPSGEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANI 200 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 L Q + VDK E+A+ IEMNEPV L+FALRY+N FTKATPLS TVT+S+S+++P+VVEYK Sbjct: 201 VLRQNTTVDKPEDAIVIEMNEPVSLSFALRYMNSFTKATPLSETVTISLSSELPVVVEYK 260 Query: 241 ISDMGHLKYYLAPKI 255 +++MG+++YYLAPKI Sbjct: 261 VAEMGYIRYYLAPKI 275 >5TUP-A nrPDB Length = 259 Score = 300 bits (767), Expect = 5e-82, Method: Compositional matrix adjust. Identities = 137/259 (52%), Positives = 201/259 (77%), Gaps = 1/259 (0%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EARL Q S+LK+V++A+KDL+ + +D + G+ LQ+MD+SHV+LV + L++EGF Y Sbjct: 2 MLEARLEQASLLKRVVDAIKDLVQDCNFDCNDSGIALQAMDNSHVALVSMLLKAEGFSPY 61 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRN+A+G+NL S++K+L+ A NEDI+TL+A+D+ D + L+FE+ +++S+Y++KLMD Sbjct: 62 RCDRNIALGINLVSLTKVLRAAQNEDILTLKADDSPDAVNLMFESAETDRISEYDIKLMD 121 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D E L IPE EY+ V+MPS EF RICRDL+ + ++VVI K+GVKFS G++G+G++ Sbjct: 122 IDQEHLAIPETEYAATVEMPSAEFQRICRDLNALSESVVIEATKEGVKFSCQGDIGSGSV 181 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 + Q ++VDK E+ V+I ++EPV LTF+L+YL F KAT LS VTL +S +VPL+VEY Sbjct: 182 TIRQHTSVDKPEQNVSIALSEPVALTFSLKYLVNFCKATSLSSKVTLCLSQEVPLLVEYG 241 Query: 241 ISDMGHLKYYLAPKIEDEE 259 + GHL++YLAPKI DEE Sbjct: 242 LGS-GHLRFYLAPKIGDEE 259 >5CFK-A nrPDB Length = 259 Score = 239 bits (610), Expect = 9e-64, Method: Compositional matrix adjust. Identities = 110/259 (42%), Positives = 175/259 (67%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA++ S+ K+++E + L+NEA +D + GG+++Q+MDSSHV+LV + LR + F Y Sbjct: 1 MLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 +C RN +G+NL S+SK+LK + D ++LR +D++D + L E P + + +Y++KL++ Sbjct: 61 QCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLE 120 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 ++ E +GIPE +Y V + S EFA+I RD+ GD V I+ +K+GVKFS+SG++G G Sbjct: 121 IEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYT 180 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 L D+ + V + M EP+ L+FALR++ F K + LS VTL + D P +VEY Sbjct: 181 FLQAAGVSDRSTKGVEVTMEEPITLSFALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYG 240 Query: 241 ISDMGHLKYYLAPKIEDEE 259 I ++G+L+YYLAPK++D E Sbjct: 241 IDNVGYLRYYLAPKVDDAE 259 >6J0J-A nrPDB Length = 302 Score = 223 bits (569), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 115/292 (39%), Positives = 179/292 (61%), Gaps = 33/292 (11%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA++ S+ K+++E + L+NEA +D + GG+++Q+MDSSHV+LV + LR + F Y Sbjct: 11 MLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKY 70 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 +C RN +G+NL S+SK+LK + D ++LR +D++D + L E P + + +Y++KL++ Sbjct: 71 QCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLE 130 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 ++ E +GIPE +Y V + S EFA+I RD+ GD V I+ +K+GVKFS+SG++G G Sbjct: 131 IEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYT 190 Query: 181 KL--------SQTSNV---------DKEEE----------------AVTIEMNEPVQLTF 207 L S S V D +EE V + M EP+ L+F Sbjct: 191 FLQAAGVSDRSTKSEVKAEVKAEARDDDEEPLSRKYGKADSSANAIGVEVTMEEPITLSF 250 Query: 208 ALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMGHLKYYLAPKIEDEE 259 ALR++ F K + LS VTL + D P +VEY I ++G+L+YYLAPK++D E Sbjct: 251 ALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYGIDNVGYLRYYLAPKVDDAE 302 >5ZUT-A nrPDB Length = 289 Score = 201 bits (512), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 93/260 (35%), Positives = 164/260 (63%), Gaps = 1/260 (0%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F Y Sbjct: 1 MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCD + +G++LTS+SKIL+C N D +TL A++ D++ L+FE ++++++Y +KLMD Sbjct: 61 RCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMD 120 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D + L I E +Y + +PS EF++I RDLS + D++ I K+ +KF A G++G+G++ Sbjct: 121 IDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSV 180 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 + +++ E ++ +EM++PV LTF +YL K + LS V + +S++ P + ++ Sbjct: 181 IIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFD 240 Query: 241 ISDMGHLKYYLAPKIEDEEG 260 + G L+++LAPK DEEG Sbjct: 241 LKS-GFLQFFLAPKFNDEEG 259 >3K4X-A nrPDB Length = 798 Score = 197 bits (502), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 91/258 (35%), Positives = 162/258 (62%), Gaps = 1/258 (0%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F Y Sbjct: 7 MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEY 66 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCD + +G++LTS+SKIL+C N D +TL A++ D++ L+FE ++++++Y +KLMD Sbjct: 67 RCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMD 126 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D + L I E +Y + +PS EF++I RDLS + D++ I K+ +KF A G++G+G++ Sbjct: 127 IDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSV 186 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 + +++ E ++ +EM++PV LTF +YL K + LS V + +S++ P + ++ Sbjct: 187 IIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFD 246 Query: 241 ISDMGHLKYYLAPKIEDE 258 + G L+++LAPK DE Sbjct: 247 LKS-GFLQFFLAPKFNDE 263 Score = 197 bits (501), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 91/257 (35%), Positives = 162/257 (63%), Gaps = 1/257 (0%) Query: 3 EARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRC 62 EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F YRC Sbjct: 543 EAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRC 602 Query: 63 DRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLD 122 D + +G++LTS+SKIL+C N D +TL A++ D++ L+FE ++++++Y +KLMD+D Sbjct: 603 DHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDID 662 Query: 123 VEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKL 182 + L I E +Y + +PS EF++I RDLS + D++ I K+ +KF A G++G+G++ + Sbjct: 663 ADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVII 722 Query: 183 SQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKIS 242 +++ E ++ +EM++PV LTF +YL K + LS V + +S++ P + ++ + Sbjct: 723 KPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLK 782 Query: 243 DMGHLKYYLAPKIEDEE 259 G L+++LAPK DEE Sbjct: 783 S-GFLQFFLAPKFNDEE 798 Score = 195 bits (496), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 90/256 (35%), Positives = 161/256 (62%), Gaps = 1/256 (0%) Query: 3 EARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRC 62 EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F YRC Sbjct: 276 EAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRC 335 Query: 63 DRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLD 122 D + +G++LTS+SKIL+C N D +TL A++ D++ L+FE ++++++Y +KLMD+D Sbjct: 336 DHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDID 395 Query: 123 VEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKL 182 + L I E +Y + +PS EF++I RDLS + D++ I K+ +KF A G++G+G++ + Sbjct: 396 ADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVII 455 Query: 183 SQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKIS 242 +++ E ++ +EM++PV LTF +YL K + LS V + +S++ P + ++ + Sbjct: 456 KPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLK 515 Query: 243 DMGHLKYYLAPKIEDE 258 G L+++LAPK DE Sbjct: 516 S-GFLQFFLAPKFNDE 530 >4L60-A nrPDB Length = 256 Score = 191 bits (485), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 89/257 (34%), Positives = 160/257 (62%), Gaps = 1/257 (0%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F Y Sbjct: 1 MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCD + +G++LTS+SKIL+ N D +TL A++ D++ L+FE ++++++Y +KLMD Sbjct: 61 RCDHPVTLGMDLTSLSKILRRGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMD 120 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D + L I E +Y + +PS EF++I RDLS + D++ I K+ +KF A G++G+G++ Sbjct: 121 IDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSV 180 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 + +++ E ++ +EM++PV LTF +YL K + LS V + +S++ P + ++ Sbjct: 181 IIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFD 240 Query: 241 ISDMGHLKYYLAPKIED 257 + G L+++LAPK D Sbjct: 241 LKS-GFLQFFLAPKFND 256 >3P91-A nrPDB Length = 265 Score = 167 bits (422), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 92/261 (35%), Positives = 158/261 (60%), Gaps = 9/261 (3%) Query: 2 FEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR 61 F A+ + ++ K+V+E+LK I++ +D S G+ +Q MD+SHVSLV L + ++ FD ++ Sbjct: 7 FHAKFKEAALFKRVVESLKSTIDKTNFDCSDAGIAVQCMDNSHVSLVSLLIETDAFDEFQ 66 Query: 62 CDRNLAMGVNLTSMSKILKCAGNED--IITLRAEDNADTLALVFEAPNQEKVSDYEMKLM 119 C + + +G+NLT +SKILK N+ I+ ++ D+A L++ E N K + + L+ Sbjct: 67 CLKPITLGINLTHLSKILKALDNDCGLILDVKKVDDA-VLSITSEGTN--KTMKFGLNLV 123 Query: 120 DLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIG-DAVVISCAKDGVKFSASGELGNG 178 D++ E + IPE + ++ + S EF +I +D S +G D++ I C K+ V + G + Sbjct: 124 DIEAESVEIPELQSDAIITLSSAEFLKITKDFSALGDDSITIGCTKNEVTLTTKGAMCET 183 Query: 179 NIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVE 238 + LS NVD + IE N+ V +FAL+ ++ F K+ PL+ V LS+S PL++E Sbjct: 184 CMTLSALENVDS--NGLQIEHNKDVTASFALKQISEFAKSAPLADNVKLSLSGQAPLIME 241 Query: 239 YKISDMGHLKYYLAPKIEDEE 259 +K + LK+YLAPK ++E+ Sbjct: 242 FK-GEACVLKFYLAPKFDEED 261 >3L0X-A nrPDB Length = 169 Score = 133 bits (335), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 60/160 (37%), Positives = 102/160 (63%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F Y Sbjct: 7 MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEY 66 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCD + +G++LTS+SKIL+C N D +TL A++ D++ L+FE ++++++Y +KLMD Sbjct: 67 RCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMD 126 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVI 160 +D + L I E +Y + +PS EF++I RDLS + D++ I Sbjct: 127 IDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINI 166 >5A6D-A nrPDB Length = 249 Score = 93.2 bits (230), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 66/237 (27%), Positives = 118/237 (49%), Gaps = 9/237 (3%) Query: 21 DLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILK 80 +LI+EA + I+ GV++++MD S V L+ L L F Y + +G+N+ KILK Sbjct: 22 NLIDEAAFKITEEGVSMRAMDPSRVVLIDLNLPESIFSKYEVEEPETIGINMDHFKKILK 81 Query: 81 CAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMP 140 ++D + LR D + L + FE + + + L+D++ +L +PE ++ V + Sbjct: 82 RGKSKDTLILRKGDE-NFLEITFEGTAKRT---FRLPLIDVEELELELPELPFTAKVVLL 137 Query: 141 SGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMN 200 +D S + D++ +D A GE IKL+ ++E + +E+ Sbjct: 138 GEVLKEAIKDASLVSDSLKFIAKEDEFTMKAEGETNEVEIKLTL-----EDEGLLDLEVE 192 Query: 201 EPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMGHLKYYLAPKIED 257 E + + + YL K + VTL T++PL ++Y I D G L + LAP++E+ Sbjct: 193 EETRSAYGISYLADMVKGIGKADEVTLRFGTEMPLQMDYFIRDEGKLTFLLAPRVEE 249 >5DA7-A nrPDB Length = 255 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 63/237 (26%), Positives = 116/237 (48%), Gaps = 9/237 (3%) Query: 21 DLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILK 80 +LI+EA + + G+++++MD S V L+ L L F Y + +G+N+ KILK Sbjct: 22 NLIDEAAFKFTEEGISMRAMDPSRVVLIDLNLPESIFSKYEVEEPETIGINMDQFKKILK 81 Query: 81 CAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMP 140 +D + LR D + L + FE + + + L+D++ +L +PE ++ V + Sbjct: 82 RGKAKDTLILRKGDE-NFLEITFEGTAK---RTFRLPLIDVEELELELPELPFTAKVVLL 137 Query: 141 SGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMN 200 +D S + DA+ ++ A GE I+L+ ++E + +E+ Sbjct: 138 GEVLKEGIKDASLVSDAIKFIAKENEFTMKAEGETNEVEIRLTL-----EDEGLLDLEVE 192 Query: 201 EPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMGHLKYYLAPKIED 257 E + + +RYL+ K + V L ++PL +EY I D G L + LAP++E+ Sbjct: 193 EETKSAYGIRYLSDMVKGIGKADEVILRFGNEMPLQMEYMIRDEGRLTFLLAPRVEE 249 >1ISQ-A nrPDB Length = 249 Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 62/237 (26%), Positives = 116/237 (48%), Gaps = 11/237 (4%) Query: 22 LINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKC 81 LI+EA + ++ G+++++MD S V L+ L L S F Y +GVNL + KILK Sbjct: 23 LIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSKYEVVEPETIGVNLDHLKKILKR 82 Query: 82 AGNEDIITL-RAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMP 140 +D + L + E+N + + A + + L+D++ ++ +PE ++ V + Sbjct: 83 GKAKDTLILKKGEENFLEITIQGTATRT-----FRVPLIDVEEMEVDLPELPFTAKVVVL 137 Query: 141 SGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMN 200 +D S + D++ ++ A GE IKL+ ++E + IE+ Sbjct: 138 GEVLKDAVKDASLVSDSIKFIARENEFIMKAEGETQEVEIKLTL-----EDEGLLDIEVQ 192 Query: 201 EPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMGHLKYYLAPKIED 257 E + + + YL+ K + VT+ ++P+ +EY I D G L + LAP++E+ Sbjct: 193 EETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLTFLLAPRVEE 249 >1UD9-A nrPDB Length = 245 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 58/244 (23%), Positives = 115/244 (47%), Gaps = 10/244 (4%) Query: 12 LKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVN 71 LK +++AL L++EA +DI G+ L ++D +H+SL+++ L E F Y G N Sbjct: 11 LKAIIQALLKLVDEALFDIKPEGIQLVAIDKAHISLIKIELPKEMFKEYDVPEEFKFGFN 70 Query: 72 LTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQ 131 MSK+LK A ++ I + A D+ + + L + ++++ +V ++ + Sbjct: 71 TQYMSKLLKAAKRKEEIIIDA-DSPEVVKLTLSGALNRVFNVNNIEVLPPEVPEVNL--- 126 Query: 132 EYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKE 191 E+ + + +++ + D ++IS ++ V GE ++ S+ + Sbjct: 127 EFDIKATINASGLKNAIGEIAEVADTLLISGNEEKVVVKGEGE-NKVEVEFSKDTG---- 181 Query: 192 EEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMGHLKYYL 251 IE N+ + + YLN T LS V ++ + P+ +E+ + G + Y L Sbjct: 182 -SLADIEFNKESSSAYDVEYLNDIISLTKLSDYVKVAFADQKPMQLEFNMEGGGKVTYLL 240 Query: 252 APKI 255 APK+ Sbjct: 241 APKL 244 >1RXZ-A nrPDB Length = 245 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 63/257 (24%), Positives = 125/257 (48%), Gaps = 20/257 (7%) Query: 6 LVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRN 65 ++ G +LK V A+ L++EA G++ +++D ++V++V + + + F+ Y D Sbjct: 5 IMTGELLKTVTRAIVALVSEARIHFLEKGLHSRAVDPANVAMVIVDIPKDSFEVYNIDEE 64 Query: 66 LAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDV-- 123 +GV++ + I K +D++ L ED + TL + F + +Y++ L+D Sbjct: 65 KTIGVDMDRIFDISKSISTKDLVELIVEDES-TLKVKFGS------VEYKVALIDPSAIR 117 Query: 124 EQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLS 183 ++ IPE E + M +GEF + I D V+ K+G + A G++ + ++ Sbjct: 118 KEPRIPELELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMT 177 Query: 184 QTSNVDKEEEAVTIEMN-EPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK-I 241 +T IE N + F++ YL F K +T+ + T+ P+ + ++ + Sbjct: 178 ETE---------LIEFNGGEARSMFSVDYLKEFCKVAGSGDLLTIHLGTNYPVRLVFELV 228 Query: 242 SDMGHLKYYLAPKIEDE 258 ++Y LAP+IE E Sbjct: 229 GGRAKVEYILAPRIESE 245 >2IX2-C nrPDB Length = 259 Score = 80.1 bits (196), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 60/247 (24%), Positives = 115/247 (46%), Gaps = 14/247 (5%) Query: 11 ILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGV 70 +LK +++AL L++EA V L ++D +H+SL+ + L E F Y + G Sbjct: 25 VLKDIIQALARLVDEAVLKFKQDSVELVALDRAHISLISVNLPREMFKEYDVNDEFKFGF 84 Query: 71 NLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPE 130 N + KILK A ++ I + +E + + + N+ E + +L+V + IPE Sbjct: 85 NTQYLMKILKVAKRKEAIEIASESPDSVIINIIGSTNR------EFNVRNLEVSEQEIPE 138 Query: 131 --QEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNV 188 ++ + S F ++S + D VV+ +D + A GE ++ S+ + Sbjct: 139 INLQFDISATISSDGFKSAISEVSTVTDNVVVEGHEDRILIKAEGE-SEVEVEFSKDTGG 197 Query: 189 DKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMGHLK 248 ++ +E ++ + +++ YL+ T LS V +S PL + + + G + Sbjct: 198 LQD-----LEFSKESKNSYSAEYLDDVLSLTKLSDYVKISFGNQKPLQLFFNMEGGGKVT 252 Query: 249 YYLAPKI 255 Y LAPK+ Sbjct: 253 YLLAPKV 259 >3IFV-A nrPDB Length = 247 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 60/261 (22%), Positives = 129/261 (49%), Gaps = 21/261 (8%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 MF+A +V + L+ L+++ L++E ++ ++++++D ++V +V LTL + F++Y Sbjct: 1 MFKA-IVSAATLRDALDSVSVLVDECKIRLNEESLSIRAVDPANVGMVDLTLDAAAFESY 59 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 + +GVNL+ + ++ AG D+I L ++ L + + + Y + L+D Sbjct: 60 EAHGGV-IGVNLSRLEEVAGMAGAGDLIHLTLDEETRKLNIRIDGLS------YTLALID 112 Query: 121 LDV--EQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISC--AKDGVKFSASGELG 176 D ++ IP+ + + + + R + + D + + A++ A G+ Sbjct: 113 PDSIRQEPDIPDLDLAANIVLEGTHLDRGIKAADMVSDHIRLRVDGAEETFHIEAEGDTD 172 Query: 177 NGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLV 236 + ++ L + ++IE L F+L YL KA P VT+ + + P+ Sbjct: 173 DVDLSLPPA-------DLISIEAGAADSL-FSLDYLKDMNKAIPTDAEVTVELGEEFPVK 224 Query: 237 VEYKISD-MGHLKYYLAPKIE 256 + Y+I++ MG + Y LAP+I+ Sbjct: 225 LHYQIAEGMGTITYMLAPRIQ 245 >2IO4-B nrPDB Length = 246 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 55/255 (21%), Positives = 116/255 (45%), Gaps = 12/255 (4%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M +A+++ +L + D ++EA + ++ G+ + +D S V + + L S F+ + Sbjct: 1 MMKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGF 60 Query: 61 RCDRNL-AMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLM 119 + +G L ++ ILK +D + L + N L L F+ E +E+ L+ Sbjct: 61 EVSQEKEIIGFKLEDVNDILKRVLKDDTLILSS--NESKLTLTFDG---EFTRSFELPLI 115 Query: 120 DLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGN 179 ++ Q E+ ++ + FA I +LS +G+ + I ++ + F G+L Sbjct: 116 QVESTQPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKENKLYFEVIGDLSTAK 175 Query: 180 IKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEY 239 ++LS + E V ++ + Y+ TK S ++ L + +PL + + Sbjct: 176 VELSTDNGTLLEASGAD------VSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRF 229 Query: 240 KISDMGHLKYYLAPK 254 K+ G+ +Y+AP+ Sbjct: 230 KLPQEGYGDFYIAPR 244 >3AIZ-C nrPDB Length = 246 Score = 70.5 bits (171), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 50/253 (19%), Positives = 113/253 (44%), Gaps = 11/253 (4%) Query: 5 RLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDR 64 +++ + L++ I+E D +S G+ ++ +D S V+ + + + + F+ Y ++ Sbjct: 4 KVIDADAFSYIFRTLEEFIDEITLDFTSDGLKIRGIDPSRVTFIDILIPAGYFEEYNVEK 63 Query: 65 NLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVE 124 +GV L + +LK D + L ++N + + + + + + + +++ Sbjct: 64 EEKVGVKLEDFTDVLKTVTKNDSLYLETDENQN-IKVTLDGVYERTFTFPSIVASEIETP 122 Query: 125 QLGIPEQEYSCVVKMPSGEFARICRDLSHI-GDAVVISCAKDGVKFSASGELGNGNIKLS 183 L + E+ K + F I ++ I GD++ + SA+ ++G+ I+LS Sbjct: 123 NLNL---EFPFKAKALTVTFTDIIDEIEDIGGDSITFKAEGGKLYLSANSDMGSSTIELS 179 Query: 184 QTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISD 243 + E E E + L Y+ +K S TV ++ + +PL + Y + Sbjct: 180 TENGGLLESEGGDAES------VYGLEYVVNTSKMRKPSDTVEIAFGSQIPLKLRYNLPQ 233 Query: 244 MGHLKYYLAPKIE 256 G+ +Y+AP+ E Sbjct: 234 GGYADFYIAPRAE 246 >3PGE-A nrPDB Length = 200 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 32/100 (32%), Positives = 61/100 (61%), Gaps = 1/100 (1%) Query: 160 ISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKAT 219 I + +KF A G++G+G++ + +++ E ++ +EM++PV LTF +YL K + Sbjct: 102 IGGGGETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGS 161 Query: 220 PLSPTVTLSMSTDVPLVVEYKISDMGHLKYYLAPKIEDEE 259 LS V + +S++ P + ++ + G L+++LAPK DEE Sbjct: 162 SLSDRVGIRLSSEAPALFQFDLKS-GFLQFFLAPKFNDEE 200 >3L0X-B nrPDB Length = 94 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 31/93 (33%), Positives = 59/93 (63%), Gaps = 1/93 (1%) Query: 167 VKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVT 226 +KF A G++G+G++ + +++ E ++ +EM++PV LTF +YL K + LS V Sbjct: 3 IKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVG 62 Query: 227 LSMSTDVPLVVEYKISDMGHLKYYLAPKIEDEE 259 + +S++ P + ++ + G L+++LAPK DEE Sbjct: 63 IRLSSEAPALFQFDLKS-GFLQFFLAPKFNDEE 94 >3LX2-A nrPDB Length = 259 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 49/250 (19%), Positives = 115/250 (46%), Gaps = 16/250 (6%) Query: 12 LKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVN 71 + ++ L+ +EA + ++ G+ ++++D S V LV L L F Y + A+ + Sbjct: 13 FESLIATLEKFFDEAVFQVNMEGIQMRAIDPSRVVLVDLNLPEMLFSKYSVESEEAIAFD 72 Query: 72 LTSMSKILKCAGNEDIITLR-AEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPE 130 L K+LK A + D + LR +N + L+ ++ + +++ L+D + ++ IP Sbjct: 73 LKRFLKVLKLARSRDTLVLRKGGENFLEVGLL-----GDENTWFKLPLIDANTPEIEIPS 127 Query: 131 QEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDK 190 ++ + +G R + + D++ + + F A G S+ V Sbjct: 128 LPWTVKAVVLAGALKRAVKAAKLVSDSIYFMATPEKLTFKAEG-------NDSEVRTVLT 180 Query: 191 EEEAVTIEMNEPV---QLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMGHL 247 E+ +++ + + + + YL ++ + V + D+PL+++Y + D G + Sbjct: 181 MEDPGLLDLEHKMTKAKSAYGVAYLEDILRSLADADEVIIRFGFDIPLLLKYMVRDAGEV 240 Query: 248 KYYLAPKIED 257 + +AP++E+ Sbjct: 241 SFLIAPRVEE 250 >6AIG-A nrPDB Length = 263 Score = 67.0 bits (162), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 57/261 (21%), Positives = 115/261 (44%), Gaps = 36/261 (13%) Query: 8 QGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGF-DTYRCD--R 64 + + K++++++ +++E + I+ G+ L+ MD + V+LV + + S F D Y Sbjct: 21 EAKVFKELVDSVSKILDEGLFIITGEGLRLRGMDPARVALVDIEIPSSSFFDFYMAGDVE 80 Query: 65 NLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEA--------PNQEKVSDYEM 116 + +GVN+ ++ ++ A D + +R + D + + E+ PN E + D Sbjct: 81 RVELGVNMETLKGVVARAKKGDQLEVRVRE--DKVLFIVESVVLRRYLLPNLEVIVD--- 135 Query: 117 KLMDLDVEQLGIPEQ---EYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASG 173 +PE E+ + + + RD+ +GD V +D + + G Sbjct: 136 -----------VPEDISLEFDATATVIADVVKKTLRDVELVGDIVEFDAGEDYLSIRSVG 184 Query: 174 -ELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTD 232 E +L++ S + +E+ EP + + YL ++ ++ LS STD Sbjct: 185 PERRRVETRLTRESPA-----LIDLEVKEPATSRYDVGYLKRMLGVAKIAESIELSFSTD 239 Query: 233 VPLVVEYKISDMGHLKYYLAP 253 PL + +K D + Y LAP Sbjct: 240 KPLKMVFKSPDGSRVTYLLAP 260 >3L10-B nrPDB Length = 169 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 56/89 (62%), Gaps = 1/89 (1%) Query: 167 VKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVT 226 +KF A G++G+G++ + +++ E ++ +EM++PV LTF +YL K + LS V Sbjct: 81 IKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVG 140 Query: 227 LSMSTDVPLVVEYKISDMGHLKYYLAPKI 255 + +S++ P + ++ + G L+++LAPK Sbjct: 141 IRLSSEAPALFQFDLKS-GFLQFFLAPKF 168 >3AIZ-A nrPDB Length = 248 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 55/255 (21%), Positives = 106/255 (41%), Gaps = 7/255 (2%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M +A +L L + +E + + + + + V +V + E + Y Sbjct: 1 MIKATYSSAKDFYSLLSGLLKVTDEIILNFTEDSIFSRYLTDDKVLMVIFKIPKEYLEDY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 D+ L + +N+ + KIL A ++ T+ E+ L + S+ +K Sbjct: 61 TIDKPLGIKININDLKKILGKAKSKSA-TVTLEETEAGLKVTVRDEKTGTRSNIYIKGEK 119 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 ++QL P+ S I RDLS +G+ V IS ++ V S E G Sbjct: 120 TSIDQLTEPKVNLSVTFTTDGDVLKDIARDLSLVGEEVEISADENTVTLSTE-EAGRTYK 178 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 L + DK +++ +E P + +++ L K T +S VT+ ++P+ +E Sbjct: 179 SLLKQ---DKPLKSLNVE--SPSKAVYSIEVLKDVFKVTSISQNVTVGFGNNIPMKIEVP 233 Query: 241 ISDMGHLKYYLAPKI 255 G L +++AP++ Sbjct: 234 TDSGGQLIFWIAPRL 248 >2HII-A nrPDB Length = 257 Score = 33.1 bits (74), Expect = 0.12, Method: Compositional matrix adjust. Identities = 45/246 (18%), Positives = 107/246 (43%), Gaps = 18/246 (7%) Query: 16 LEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSM 75 + ++ ++ + + + G+ + + V + + + + Y D ++ ++++S+ Sbjct: 16 INSITNVTDSIILNFTEDGIFSRHLTEDKVLMAIMRIPKDVLSEYSIDSPTSVKLDVSSV 75 Query: 76 SKIL-KCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYS 134 KIL K + + I L D+ L ++ S +K VEQL P+ + Sbjct: 76 KKILSKASSKKATIELTETDSG--LKIIIRDEKSGAKSTIYIKAEKGQVEQLTEPKVNLA 133 Query: 135 CVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEA 194 I D++ +G+ + IS +D +K A GE G + DK + Sbjct: 134 VNFTTDESVLNVIAADVTLVGEEMRISTEEDKIKIEA-GEEGKRYVAFLMK---DKPLKE 189 Query: 195 VTIEMNEPVQLTF-----ALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMGHLKY 249 ++I+ + + A++ L F+ +PT+ +S ++P+ ++ + GH+ + Sbjct: 190 LSIDTSASSSYSAEMFKDAVKGLRGFS-----APTM-VSFGENLPMKIDVEAVSGGHMIF 243 Query: 250 YLAPKI 255 ++AP++ Sbjct: 244 WIAPRL 249 >6HUM-J nrPDB Length = 168 Score = 28.9 bits (63), Expect = 2.5, Method: Compositional matrix adjust. Identities = 25/124 (20%), Positives = 55/124 (44%), Gaps = 12/124 (9%) Query: 3 EARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRC 62 EA +V+ + ++L++ + D S GV + +D + V TL ++GF+ RC Sbjct: 6 EAPIVEAGPVGRLLQSQNLSVESLGRDAS--GVEMIKVDRDRLLAVCQTLYADGFNYLRC 63 Query: 63 D--RNLAMGVNLTSMSKILKCAGNED--------IITLRAEDNADTLALVFEAPNQEKVS 112 + G +L S ++K + N D + R + ++ +++ + ++ Sbjct: 64 QAAYDSGPGQDLVSTYHLIKLSDNADRPPEVRIKVFVPRDDPRVPSVYWIWKTADWQERE 123 Query: 113 DYEM 116 Y+M Sbjct: 124 SYDM 127 >4HJV-A nrPDB Length = 203 Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust. Identities = 29/118 (24%), Positives = 48/118 (40%), Gaps = 25/118 (21%) Query: 30 ISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR---------------CDRNLAMGVNLTS 74 I SGG S+ + L+QL + G D YR +RN++MG + Sbjct: 63 IESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLN 122 Query: 75 MSKILKCAGNEDIITLR------AEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQL 126 + + AG ED L+ + A L F + ++ +S K+ DLD ++ Sbjct: 123 ILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAIS----KINDLDADEF 176 >6D46-A nrPDB Length = 389 Score = 27.3 bits (59), Expect = 6.8, Method: Compositional matrix adjust. Identities = 15/56 (26%), Positives = 27/56 (48%), Gaps = 1/56 (1%) Query: 55 EGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEK 110 E F Y CD +L +G N + +LK A +++ L D + + ++ + P K Sbjct: 325 ESFYEYNCDESLVIGFNPQYLEDVLK-AVKSNLVELYFSDISASAPVLIKFPQNPK 379 >2AW5-A nrPDB Length = 575 Score = 26.9 bits (58), Expect = 8.1, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 10/76 (13%) Query: 112 SDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIG--------DAVVISCA 163 SD E + + +G+ Q+YS V + P G F I D HI D + Sbjct: 103 SDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITI-HDRGHIASVLNAWPEDVIKAIVV 161 Query: 164 KDGVKFSASGELG-NG 178 DG + G+LG NG Sbjct: 162 TDGERILGLGDLGCNG 177 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5IY4-A nrPDB 344 2e-95 4CS5-A nrPDB 333 4e-92 4HK1-A nrPDB 328 2e-90 6O09-C nrPDB 324 3e-89 2ZVW-A nrPDB 315 2e-86 5TUP-A nrPDB 307 3e-84 5CFK-A nrPDB 290 4e-79 5ZUT-A nrPDB 287 3e-78 3K4X-A nrPDB 283 7e-77 4L60-A nrPDB 277 3e-75 6J0J-A nrPDB 270 3e-73 1ISQ-A nrPDB 246 1e-65 3P91-A nrPDB 239 1e-63 5DA7-A nrPDB 237 4e-63 5A6D-A nrPDB 233 9e-62 2IO4-B nrPDB 223 8e-59 3AIZ-C nrPDB 220 6e-58 3LX2-A nrPDB 219 1e-57 1UD9-A nrPDB 210 6e-55 2IX2-C nrPDB 209 1e-54 3AIZ-A nrPDB 204 4e-53 1RXZ-A nrPDB 195 1e-50 3IFV-A nrPDB 193 6e-50 6AIG-A nrPDB 184 4e-47 3L0X-A nrPDB 182 1e-46 3L10-B nrPDB 105 2e-23 3PGE-A nrPDB 105 2e-23 3L0X-B nrPDB 102 1e-22 Sequences not found previously or not previously below threshold: 2HII-A nrPDB 134 3e-32 5W7Z-A nrPDB 39 0.003 6D46-A nrPDB 37 0.007 3A1J-A nrPDB 36 0.017 6MAN-A nrPDB 34 0.095 5NNN-A nrPDB 31 0.54 4WED-A nrPDB 28 2.9 4TR8-A nrPDB 28 5.6 3T6Z-A nrPDB 27 6.3 5GAF-i nrPDB 27 8.1 5U8T-C nrPDB 27 9.2 >5IY4-A nrPDB Length = 270 Score = 344 bits (883), Expect = 2e-95, Method: Composition-based stats. Identities = 257/261 (98%), Positives = 258/261 (98%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 MFEARLVQGSILKKVLEALKDLINEACWDISS GVNLQSMDSSHVSLVQLTLRSEGFDTY Sbjct: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD Sbjct: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI Sbjct: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLS TVTLSMS DVPLVVEYK Sbjct: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYK 240 Query: 241 ISDMGHLKYYLAPKIEDEEGS 261 I+DMGHLKYYLAPKIEDEEGS Sbjct: 241 IADMGHLKYYLAPKIEDEEGS 261 >4CS5-A nrPDB Length = 260 Score = 333 bits (855), Expect = 4e-92, Method: Composition-based stats. Identities = 191/259 (73%), Positives = 230/259 (88%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 MFEARLVQGS+LKKVLEA+KDL+NEA WD + G+ LQ+MD+SHVSLV L LR++GFD Y Sbjct: 1 MFEARLVQGSLLKKVLEAIKDLLNEASWDCADSGIQLQAMDNSHVSLVSLNLRAKGFDKY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRNL MG+NLTSMSKILKCA N+DIIT++A+DNADT+ +FE+PNQEKVSDYEMKLM+ Sbjct: 61 RCDRNLIMGMNLTSMSKILKCAANDDIITMKAQDNADTVTFMFESPNQEKVSDYEMKLMN 120 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 LD E LGIPE +Y+CV+K+PSGEFARICRDLS G+++VI+C K+GVKFSA+G++G NI Sbjct: 121 LDQEHLGIPETDYACVIKLPSGEFARICRDLSQFGESIVIACTKEGVKFSAAGDIGTANI 180 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 KL+QTS+VDKEEEAV IEM EPV LTFA RYLN FTKATPLSP V+LSMS DVPLVVEY Sbjct: 181 KLAQTSSVDKEEEAVVIEMQEPVTLTFACRYLNMFTKATPLSPQVSLSMSPDVPLVVEYA 240 Query: 241 ISDMGHLKYYLAPKIEDEE 259 I ++GH++Y+LAPKIEDE+ Sbjct: 241 IGEIGHIRYFLAPKIEDED 259 >4HK1-A nrPDB Length = 263 Score = 328 bits (841), Expect = 2e-90, Method: Composition-based stats. Identities = 182/259 (70%), Positives = 220/259 (84%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 MFEARL Q +ILKK+L+A+KDL+NEA +D S G+ LQ+MD+SHVSLV LTLRS+GFD + Sbjct: 4 MFEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKF 63 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRNL+MG+NL SM+KILKCA NED +T++A+DNADT+ ++FE+ NQEKVSDYEMKLM+ Sbjct: 64 RCDRNLSMGMNLGSMAKILKCANNEDNVTMKAQDNADTVTIMFESANQEKVSDYEMKLMN 123 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 LD E LGIPE ++SCVV+MP+ EFARICRDL+ ++VVI C K+GVKFSASG++G NI Sbjct: 124 LDQEHLGIPETDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANI 183 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 KL+QT +VDKEEEAV IEM EPV LTFA RYLN FTKATPLS V LSM DVPLVVEY Sbjct: 184 KLAQTGSVDKEEEAVIIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYA 243 Query: 241 ISDMGHLKYYLAPKIEDEE 259 I D+GH++YYLAPKIED E Sbjct: 244 IKDLGHIRYYLAPKIEDNE 262 >6O09-C nrPDB Length = 312 Score = 324 bits (830), Expect = 3e-89, Method: Composition-based stats. Identities = 168/261 (64%), Positives = 222/261 (85%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M E RLVQGS+LKKVLE++KDL+N+A +D SS G +LQ+MDSSHV+LV L LRSEGF+ Y Sbjct: 50 MLELRLVQGSLLKKVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSEGFEHY 109 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRNL+MG+NL +MSK+LKCAGN+DIIT++A+D DT+ +FE+P Q+K++D+EMKLMD Sbjct: 110 RCDRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMD 169 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D E LGIP+ EY +V+MPS EF+RIC+DLS IGD VVIS K+GVKFS +G++G NI Sbjct: 170 IDSEHLGIPDAEYHSIVRMPSNEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANI 229 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 L Q + VDK E+A+ IEM EPV L+FALRY+N FTKATPLS TVT+S+S+++P+VVEYK Sbjct: 230 VLRQNTTVDKPEDAIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYK 289 Query: 241 ISDMGHLKYYLAPKIEDEEGS 261 +++MG+++YYLAPKIE+EE + Sbjct: 290 VAEMGYIRYYLAPKIEEEEDT 310 >2ZVW-A nrPDB Length = 275 Score = 315 bits (806), Expect = 2e-86, Method: Composition-based stats. Identities = 167/255 (65%), Positives = 220/255 (86%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M E RLVQGS+LKKVLEA+KDL+N+A +D S+ G +LQ+MDSSHV+LV L LRSEGF+ Y Sbjct: 21 MLELRLVQGSLLKKVLEAVKDLVNDANFDCSTTGFSLQAMDSSHVALVSLLLRSEGFEHY 80 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRNL+MG+NL +MSK+LKCAGN+DIIT++A+D +DT+ +FE+P Q+K++D+EMKLMD Sbjct: 81 RCDRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGSDTVTFMFESPTQDKIADFEMKLMD 140 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D E LGIP+ EY +V+MPSGEF+RIC+DLS IGD VVIS K+GVKFS +G++G NI Sbjct: 141 IDSEHLGIPDAEYHSIVRMPSGEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANI 200 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 L Q + VDK E+A+ IEMNEPV L+FALRY+N FTKATPLS TVT+S+S+++P+VVEYK Sbjct: 201 VLRQNTTVDKPEDAIVIEMNEPVSLSFALRYMNSFTKATPLSETVTISLSSELPVVVEYK 260 Query: 241 ISDMGHLKYYLAPKI 255 +++MG+++YYLAPKI Sbjct: 261 VAEMGYIRYYLAPKI 275 >5TUP-A nrPDB Length = 259 Score = 307 bits (787), Expect = 3e-84, Method: Composition-based stats. Identities = 137/259 (52%), Positives = 201/259 (77%), Gaps = 1/259 (0%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EARL Q S+LK+V++A+KDL+ + +D + G+ LQ+MD+SHV+LV + L++EGF Y Sbjct: 2 MLEARLEQASLLKRVVDAIKDLVQDCNFDCNDSGIALQAMDNSHVALVSMLLKAEGFSPY 61 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCDRN+A+G+NL S++K+L+ A NEDI+TL+A+D+ D + L+FE+ +++S+Y++KLMD Sbjct: 62 RCDRNIALGINLVSLTKVLRAAQNEDILTLKADDSPDAVNLMFESAETDRISEYDIKLMD 121 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D E L IPE EY+ V+MPS EF RICRDL+ + ++VVI K+GVKFS G++G+G++ Sbjct: 122 IDQEHLAIPETEYAATVEMPSAEFQRICRDLNALSESVVIEATKEGVKFSCQGDIGSGSV 181 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 + Q ++VDK E+ V+I ++EPV LTF+L+YL F KAT LS VTL +S +VPL+VEY Sbjct: 182 TIRQHTSVDKPEQNVSIALSEPVALTFSLKYLVNFCKATSLSSKVTLCLSQEVPLLVEYG 241 Query: 241 ISDMGHLKYYLAPKIEDEE 259 + GHL++YLAPKI DEE Sbjct: 242 LGS-GHLRFYLAPKIGDEE 259 >5CFK-A nrPDB Length = 259 Score = 290 bits (742), Expect = 4e-79, Method: Composition-based stats. Identities = 110/259 (42%), Positives = 175/259 (67%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA++ S+ K+++E + L+NEA +D + GG+++Q+MDSSHV+LV + LR + F Y Sbjct: 1 MLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 +C RN +G+NL S+SK+LK + D ++LR +D++D + L E P + + +Y++KL++ Sbjct: 61 QCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLE 120 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 ++ E +GIPE +Y V + S EFA+I RD+ GD V I+ +K+GVKFS+SG++G G Sbjct: 121 IEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYT 180 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 L D+ + V + M EP+ L+FALR++ F K + LS VTL + D P +VEY Sbjct: 181 FLQAAGVSDRSTKGVEVTMEEPITLSFALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYG 240 Query: 241 ISDMGHLKYYLAPKIEDEE 259 I ++G+L+YYLAPK++D E Sbjct: 241 IDNVGYLRYYLAPKVDDAE 259 >5ZUT-A nrPDB Length = 289 Score = 287 bits (735), Expect = 3e-78, Method: Composition-based stats. Identities = 93/260 (35%), Positives = 164/260 (63%), Gaps = 1/260 (0%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F Y Sbjct: 1 MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCD + +G++LTS+SKIL+C N D +TL A++ D++ L+FE ++++++Y +KLMD Sbjct: 61 RCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMD 120 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D + L I E +Y + +PS EF++I RDLS + D++ I K+ +KF A G++G+G++ Sbjct: 121 IDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSV 180 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 + +++ E ++ +EM++PV LTF +YL K + LS V + +S++ P + ++ Sbjct: 181 IIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFD 240 Query: 241 ISDMGHLKYYLAPKIEDEEG 260 + G L+++LAPK DEEG Sbjct: 241 LKS-GFLQFFLAPKFNDEEG 259 >3K4X-A nrPDB Length = 798 Score = 283 bits (723), Expect = 7e-77, Method: Composition-based stats. Identities = 91/258 (35%), Positives = 162/258 (62%), Gaps = 1/258 (0%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F Y Sbjct: 7 MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEY 66 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCD + +G++LTS+SKIL+C N D +TL A++ D++ L+FE ++++++Y +KLMD Sbjct: 67 RCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMD 126 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D + L I E +Y + +PS EF++I RDLS + D++ I K+ +KF A G++G+G++ Sbjct: 127 IDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSV 186 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 + +++ E ++ +EM++PV LTF +YL K + LS V + +S++ P + ++ Sbjct: 187 IIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFD 246 Query: 241 ISDMGHLKYYLAPKIEDE 258 + G L+++LAPK DE Sbjct: 247 LKS-GFLQFFLAPKFNDE 263 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 91/258 (35%), Positives = 162/258 (62%), Gaps = 1/258 (0%) Query: 2 FEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR 61 EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F YR Sbjct: 542 LEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYR 601 Query: 62 CDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDL 121 CD + +G++LTS+SKIL+C N D +TL A++ D++ L+FE ++++++Y +KLMD+ Sbjct: 602 CDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDI 661 Query: 122 DVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIK 181 D + L I E +Y + +PS EF++I RDLS + D++ I K+ +KF A G++G+G++ Sbjct: 662 DADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVI 721 Query: 182 LSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKI 241 + +++ E ++ +EM++PV LTF +YL K + LS V + +S++ P + ++ + Sbjct: 722 IKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDL 781 Query: 242 SDMGHLKYYLAPKIEDEE 259 G L+++LAPK DEE Sbjct: 782 KS-GFLQFFLAPKFNDEE 798 Score = 280 bits (715), Expect = 5e-76, Method: Composition-based stats. Identities = 90/257 (35%), Positives = 161/257 (62%), Gaps = 1/257 (0%) Query: 2 FEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR 61 EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F YR Sbjct: 275 LEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYR 334 Query: 62 CDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDL 121 CD + +G++LTS+SKIL+C N D +TL A++ D++ L+FE ++++++Y +KLMD+ Sbjct: 335 CDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDI 394 Query: 122 DVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIK 181 D + L I E +Y + +PS EF++I RDLS + D++ I K+ +KF A G++G+G++ Sbjct: 395 DADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVI 454 Query: 182 LSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKI 241 + +++ E ++ +EM++PV LTF +YL K + LS V + +S++ P + ++ + Sbjct: 455 IKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDL 514 Query: 242 SDMGHLKYYLAPKIEDE 258 G L+++LAPK DE Sbjct: 515 KS-GFLQFFLAPKFNDE 530 >4L60-A nrPDB Length = 256 Score = 277 bits (709), Expect = 3e-75, Method: Composition-based stats. Identities = 89/257 (34%), Positives = 160/257 (62%), Gaps = 1/257 (0%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F Y Sbjct: 1 MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCD + +G++LTS+SKIL+ N D +TL A++ D++ L+FE ++++++Y +KLMD Sbjct: 61 RCDHPVTLGMDLTSLSKILRRGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMD 120 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 +D + L I E +Y + +PS EF++I RDLS + D++ I K+ +KF A G++G+G++ Sbjct: 121 IDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSV 180 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 + +++ E ++ +EM++PV LTF +YL K + LS V + +S++ P + ++ Sbjct: 181 IIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFD 240 Query: 241 ISDMGHLKYYLAPKIED 257 + G L+++LAPK D Sbjct: 241 LKS-GFLQFFLAPKFND 256 >6J0J-A nrPDB Length = 302 Score = 270 bits (691), Expect = 3e-73, Method: Composition-based stats. Identities = 110/292 (37%), Positives = 175/292 (59%), Gaps = 33/292 (11%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA++ S+ K+++E + L+NEA +D + GG+++Q+MDSSHV+LV + LR + F Y Sbjct: 11 MLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKY 70 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 +C RN +G+NL S+SK+LK + D ++LR +D++D + L E P + + +Y++KL++ Sbjct: 71 QCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLE 130 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 ++ E +GIPE +Y V + S EFA+I RD+ GD V I+ +K+GVKFS+SG++G G Sbjct: 131 IEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYT 190 Query: 181 KLSQTSNVDKEEE---------------------------------AVTIEMNEPVQLTF 207 L D+ + V + M EP+ L+F Sbjct: 191 FLQAAGVSDRSTKSEVKAEVKAEARDDDEEPLSRKYGKADSSANAIGVEVTMEEPITLSF 250 Query: 208 ALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMGHLKYYLAPKIEDEE 259 ALR++ F K + LS VTL + D P +VEY I ++G+L+YYLAPK++D E Sbjct: 251 ALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYGIDNVGYLRYYLAPKVDDAE 302 >1ISQ-A nrPDB Length = 249 Score = 246 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 62/256 (24%), Positives = 121/256 (47%), Gaps = 9/256 (3%) Query: 2 FEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR 61 FE ++++ LI+EA + ++ G+++++MD S V L+ L L S F Y Sbjct: 3 FEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSKYE 62 Query: 62 CDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDL 121 +GVNL + KILK +D + L+ + + L + + + + L+D+ Sbjct: 63 VVEPETIGVNLDHLKKILKRGKAKDTLILKKGEE-NFLEITIQGTATRT---FRVPLIDV 118 Query: 122 DVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIK 181 + ++ +PE ++ V + +D S + D++ ++ A GE IK Sbjct: 119 EEMEVDLPELPFTAKVVVLGEVLKDAVKDASLVSDSIKFIARENEFIMKAEGETQEVEIK 178 Query: 182 LSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKI 241 L+ ++E + IE+ E + + + YL+ K + VT+ ++P+ +EY I Sbjct: 179 LT-----LEDEGLLDIEVQEETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYI 233 Query: 242 SDMGHLKYYLAPKIED 257 D G L + LAP++E+ Sbjct: 234 RDEGRLTFLLAPRVEE 249 >3P91-A nrPDB Length = 265 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 90/260 (34%), Positives = 155/260 (59%), Gaps = 7/260 (2%) Query: 2 FEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR 61 F A+ + ++ K+V+E+LK I++ +D S G+ +Q MD+SHVSLV L + ++ FD ++ Sbjct: 7 FHAKFKEAALFKRVVESLKSTIDKTNFDCSDAGIAVQCMDNSHVSLVSLLIETDAFDEFQ 66 Query: 62 CDRNLAMGVNLTSMSKILKCAGNEDIITLRAED-NADTLALVFEAPNQEKVSDYEMKLMD 120 C + + +G+NLT +SKILK N+ + L + + L++ E N K + + L+D Sbjct: 67 CLKPITLGINLTHLSKILKALDNDCGLILDVKKVDDAVLSITSEGTN--KTMKFGLNLVD 124 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIG-DAVVISCAKDGVKFSASGELGNGN 179 ++ E + IPE + ++ + S EF +I +D S +G D++ I C K+ V + G + Sbjct: 125 IEAESVEIPELQSDAIITLSSAEFLKITKDFSALGDDSITIGCTKNEVTLTTKGAMCETC 184 Query: 180 IKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEY 239 + LS NVD + IE N+ V +FAL+ ++ F K+ PL+ V LS+S PL++E+ Sbjct: 185 MTLSALENVD--SNGLQIEHNKDVTASFALKQISEFAKSAPLADNVKLSLSGQAPLIMEF 242 Query: 240 KISDMGHLKYYLAPKIEDEE 259 K + LK+YLAPK ++E+ Sbjct: 243 K-GEACVLKFYLAPKFDEED 261 >5DA7-A nrPDB Length = 255 Score = 237 bits (604), Expect = 4e-63, Method: Composition-based stats. Identities = 65/256 (25%), Positives = 120/256 (46%), Gaps = 9/256 (3%) Query: 2 FEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR 61 FE ++ +LI+EA + + G+++++MD S V L+ L L F Y Sbjct: 3 FEVVFDGAKEFADLIATASNLIDEAAFKFTEEGISMRAMDPSRVVLIDLNLPESIFSKYE 62 Query: 62 CDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDL 121 + +G+N+ KILK +D + LR D + L + FE + + + L+D+ Sbjct: 63 VEEPETIGINMDQFKKILKRGKAKDTLILRKGDE-NFLEITFEGTAKRT---FRLPLIDV 118 Query: 122 DVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIK 181 + +L +PE ++ V + +D S + DA+ ++ A GE I+ Sbjct: 119 EELELELPELPFTAKVVLLGEVLKEGIKDASLVSDAIKFIAKENEFTMKAEGETNEVEIR 178 Query: 182 LSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKI 241 L+ ++E + +E+ E + + +RYL+ K + V L ++PL +EY I Sbjct: 179 LT-----LEDEGLLDLEVEEETKSAYGIRYLSDMVKGIGKADEVILRFGNEMPLQMEYMI 233 Query: 242 SDMGHLKYYLAPKIED 257 D G L + LAP++E+ Sbjct: 234 RDEGRLTFLLAPRVEE 249 >5A6D-A nrPDB Length = 249 Score = 233 bits (593), Expect = 9e-62, Method: Composition-based stats. Identities = 68/256 (26%), Positives = 122/256 (47%), Gaps = 9/256 (3%) Query: 2 FEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR 61 FE ++ +LI+EA + I+ GV++++MD S V L+ L L F Y Sbjct: 3 FEIVFDGAKEFADLIATASNLIDEAAFKITEEGVSMRAMDPSRVVLIDLNLPESIFSKYE 62 Query: 62 CDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDL 121 + +G+N+ KILK ++D + LR D + L + FE + + + L+D+ Sbjct: 63 VEEPETIGINMDHFKKILKRGKSKDTLILRKGDE-NFLEITFEGTAKRT---FRLPLIDV 118 Query: 122 DVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIK 181 + +L +PE ++ V + +D S + D++ +D A GE IK Sbjct: 119 EELELELPELPFTAKVVLLGEVLKEAIKDASLVSDSLKFIAKEDEFTMKAEGETNEVEIK 178 Query: 182 LSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKI 241 L+ ++E + +E+ E + + + YL K + VTL T++PL ++Y I Sbjct: 179 LT-----LEDEGLLDLEVEEETRSAYGISYLADMVKGIGKADEVTLRFGTEMPLQMDYFI 233 Query: 242 SDMGHLKYYLAPKIED 257 D G L + LAP++E+ Sbjct: 234 RDEGKLTFLLAPRVEE 249 >2IO4-B nrPDB Length = 246 Score = 223 bits (567), Expect = 8e-59, Method: Composition-based stats. Identities = 55/257 (21%), Positives = 117/257 (45%), Gaps = 12/257 (4%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M +A+++ +L + D ++EA + ++ G+ + +D S V + + L S F+ + Sbjct: 1 MMKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGF 60 Query: 61 RCDRN-LAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLM 119 + +G L ++ ILK +D + L + N L L F+ E +E+ L+ Sbjct: 61 EVSQEKEIIGFKLEDVNDILKRVLKDDTLILSS--NESKLTLTFDG---EFTRSFELPLI 115 Query: 120 DLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGN 179 ++ Q E+ ++ + FA I +LS +G+ + I ++ + F G+L Sbjct: 116 QVESTQPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKENKLYFEVIGDLSTAK 175 Query: 180 IKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEY 239 ++LS + E V ++ + Y+ TK S ++ L + +PL + + Sbjct: 176 VELSTDNGTLLEASGAD------VSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRF 229 Query: 240 KISDMGHLKYYLAPKIE 256 K+ G+ +Y+AP+ + Sbjct: 230 KLPQEGYGDFYIAPRAD 246 >3AIZ-C nrPDB Length = 246 Score = 220 bits (560), Expect = 6e-58, Method: Composition-based stats. Identities = 50/256 (19%), Positives = 112/256 (43%), Gaps = 11/256 (4%) Query: 2 FEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR 61 +++ + L++ I+E D +S G+ ++ +D S V+ + + + + F+ Y Sbjct: 1 MRVKVIDADAFSYIFRTLEEFIDEITLDFTSDGLKIRGIDPSRVTFIDILIPAGYFEEYN 60 Query: 62 CDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDL 121 ++ +GV L + +LK D + L ++N + + + + + + + ++ Sbjct: 61 VEKEEKVGVKLEDFTDVLKTVTKNDSLYLETDENQN-IKVTLDGVYERTFTFPSIVASEI 119 Query: 122 DVEQLGIPEQEYSCVVKMPSGEFARICRDLSHI-GDAVVISCAKDGVKFSASGELGNGNI 180 + L E+ K + F I ++ I GD++ + SA+ ++G+ I Sbjct: 120 ETPNLN---LEFPFKAKALTVTFTDIIDEIEDIGGDSITFKAEGGKLYLSANSDMGSSTI 176 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 +LS + E E E + L Y+ +K S TV ++ + +PL + Y Sbjct: 177 ELSTENGGLLESEGGDAE------SVYGLEYVVNTSKMRKPSDTVEIAFGSQIPLKLRYN 230 Query: 241 ISDMGHLKYYLAPKIE 256 + G+ +Y+AP+ E Sbjct: 231 LPQGGYADFYIAPRAE 246 >3LX2-A nrPDB Length = 259 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 50/258 (19%), Positives = 115/258 (44%), Gaps = 12/258 (4%) Query: 2 FEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR 61 FE + ++ L+ +EA + ++ G+ ++++D S V LV L L F Y Sbjct: 3 FEIVFDSAREFESLIATLEKFFDEAVFQVNMEGIQMRAIDPSRVVLVDLNLPEMLFSKYS 62 Query: 62 CDRNLAMGVNLTSMSKILKCAGNEDIITLR-AEDNADTLALVFEAPNQEKVSDYEMKLMD 120 + A+ +L K+LK A + D + LR +N + L+ ++ + +++ L+D Sbjct: 63 VESEEAIAFDLKRFLKVLKLARSRDTLVLRKGGENFLEVGLL-----GDENTWFKLPLID 117 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 + ++ IP ++ + +G R + + D++ + + F A G Sbjct: 118 ANTPEIEIPSLPWTVKAVVLAGALKRAVKAAKLVSDSIYFMATPEKLTFKAEGNDSEVRT 177 Query: 181 KLSQTSNVDKEEEAVTIEMN-EPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEY 239 L+ ++ + +E + + + YL ++ + V + D+PL+++Y Sbjct: 178 VLT-----MEDPGLLDLEHKMTKAKSAYGVAYLEDILRSLADADEVIIRFGFDIPLLLKY 232 Query: 240 KISDMGHLKYYLAPKIED 257 + D G + + +AP++E+ Sbjct: 233 MVRDAGEVSFLIAPRVEE 250 >1UD9-A nrPDB Length = 245 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 58/250 (23%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Query: 6 LVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRN 65 LK +++AL L++EA +DI G+ L ++D +H+SL+++ L E F Y Sbjct: 5 YDDVRDLKAIIQALLKLVDEALFDIKPEGIQLVAIDKAHISLIKIELPKEMFKEYDVPEE 64 Query: 66 LAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQ 125 G N MSK+LK A ++ I + A D+ + + L + ++++ +V + Sbjct: 65 FKFGFNTQYMSKLLKAAKRKEEIIIDA-DSPEVVKLTLSGALNRVFNVNNIEVLPPEVPE 123 Query: 126 LGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQT 185 + E+ + + +++ + D ++IS ++ V GE ++ S+ Sbjct: 124 VN---LEFDIKATINASGLKNAIGEIAEVADTLLISGNEEKVVVKGEGE-NKVEVEFSKD 179 Query: 186 SNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMG 245 + IE N+ + + YLN T LS V ++ + P+ +E+ + G Sbjct: 180 TG-----SLADIEFNKESSSAYDVEYLNDIISLTKLSDYVKVAFADQKPMQLEFNMEGGG 234 Query: 246 HLKYYLAPKI 255 + Y LAPK+ Sbjct: 235 KVTYLLAPKL 244 >2IX2-C nrPDB Length = 259 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 60/256 (23%), Positives = 115/256 (44%), Gaps = 14/256 (5%) Query: 2 FEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYR 61 + +LK +++AL L++EA V L ++D +H+SL+ + L E F Y Sbjct: 16 MKVVYDDVRVLKDIIQALARLVDEAVLKFKQDSVELVALDRAHISLISVNLPREMFKEYD 75 Query: 62 CDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDL 121 + G N + KILK A ++ I + +E + + + N+ E + +L Sbjct: 76 VNDEFKFGFNTQYLMKILKVAKRKEAIEIASESPDSVIINIIGSTNR------EFNVRNL 129 Query: 122 DVEQLGIPE--QEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGN 179 +V + IPE ++ + S F ++S + D VV+ +D + A GE Sbjct: 130 EVSEQEIPEINLQFDISATISSDGFKSAISEVSTVTDNVVVEGHEDRILIKAEGE-SEVE 188 Query: 180 IKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEY 239 ++ S+ + + +E ++ + +++ YL+ T LS V +S PL + + Sbjct: 189 VEFSKDTGGLQ-----DLEFSKESKNSYSAEYLDDVLSLTKLSDYVKISFGNQKPLQLFF 243 Query: 240 KISDMGHLKYYLAPKI 255 + G + Y LAPK+ Sbjct: 244 NMEGGGKVTYLLAPKV 259 >3AIZ-A nrPDB Length = 248 Score = 204 bits (518), Expect = 4e-53, Method: Composition-based stats. Identities = 55/255 (21%), Positives = 106/255 (41%), Gaps = 7/255 (2%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M +A +L L + +E + + + + + V +V + E + Y Sbjct: 1 MIKATYSSAKDFYSLLSGLLKVTDEIILNFTEDSIFSRYLTDDKVLMVIFKIPKEYLEDY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 D+ L + +N+ + KIL A ++ T+ E+ L + S+ +K Sbjct: 61 TIDKPLGIKININDLKKILGKAKSKSA-TVTLEETEAGLKVTVRDEKTGTRSNIYIKGEK 119 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 ++QL P+ S I RDLS +G+ V IS ++ V S E G Sbjct: 120 TSIDQLTEPKVNLSVTFTTDGDVLKDIARDLSLVGEEVEISADENTVTLSTE-EAGRTYK 178 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYK 240 L + DK +++ +E P + +++ L K T +S VT+ ++P+ +E Sbjct: 179 SLLKQ---DKPLKSLNVE--SPSKAVYSIEVLKDVFKVTSISQNVTVGFGNNIPMKIEVP 233 Query: 241 ISDMGHLKYYLAPKI 255 G L +++AP++ Sbjct: 234 TDSGGQLIFWIAPRL 248 >1RXZ-A nrPDB Length = 245 Score = 195 bits (496), Expect = 1e-50, Method: Composition-based stats. Identities = 63/257 (24%), Positives = 124/257 (48%), Gaps = 20/257 (7%) Query: 6 LVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRN 65 ++ G +LK V A+ L++EA G++ +++D ++V++V + + + F+ Y D Sbjct: 5 IMTGELLKTVTRAIVALVSEARIHFLEKGLHSRAVDPANVAMVIVDIPKDSFEVYNIDEE 64 Query: 66 LAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDV-- 123 +GV++ + I K +D++ L ED TL + F + +Y++ L+D Sbjct: 65 KTIGVDMDRIFDISKSISTKDLVELIVEDE-STLKVKFGS------VEYKVALIDPSAIR 117 Query: 124 EQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLS 183 ++ IPE E + M +GEF + I D V+ K+G + A G++ + ++ Sbjct: 118 KEPRIPELELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMT 177 Query: 184 QTSNVDKEEEAVTIEMN-EPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKI- 241 +T IE N + F++ YL F K +T+ + T+ P+ + +++ Sbjct: 178 ETE---------LIEFNGGEARSMFSVDYLKEFCKVAGSGDLLTIHLGTNYPVRLVFELV 228 Query: 242 SDMGHLKYYLAPKIEDE 258 ++Y LAP+IE E Sbjct: 229 GGRAKVEYILAPRIESE 245 >3IFV-A nrPDB Length = 247 Score = 193 bits (491), Expect = 6e-50, Method: Composition-based stats. Identities = 58/263 (22%), Positives = 128/263 (48%), Gaps = 21/263 (7%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 MF+A +V + L+ L+++ L++E ++ ++++++D ++V +V LTL + F++Y Sbjct: 1 MFKA-IVSAATLRDALDSVSVLVDECKIRLNEESLSIRAVDPANVGMVDLTLDAAAFESY 59 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 + +GVNL+ + ++ AG D+I L ++ L + + + Y + L+D Sbjct: 60 EAHGGV-IGVNLSRLEEVAGMAGAGDLIHLTLDEETRKLNIRIDGLS------YTLALID 112 Query: 121 LDV--EQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCA--KDGVKFSASGELG 176 D ++ IP+ + + + + R + + D + + ++ A G+ Sbjct: 113 PDSIRQEPDIPDLDLAANIVLEGTHLDRGIKAADMVSDHIRLRVDGAEETFHIEAEGDTD 172 Query: 177 NGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLV 236 + ++ L + ++IE L F+L YL KA P VT+ + + P+ Sbjct: 173 DVDLSLP-------PADLISIEAGAADSL-FSLDYLKDMNKAIPTDAEVTVELGEEFPVK 224 Query: 237 VEYKISDM-GHLKYYLAPKIEDE 258 + Y+I++ G + Y LAP+I+ + Sbjct: 225 LHYQIAEGMGTITYMLAPRIQSD 247 >6AIG-A nrPDB Length = 263 Score = 184 bits (466), Expect = 4e-47, Method: Composition-based stats. Identities = 53/250 (21%), Positives = 115/250 (46%), Gaps = 14/250 (5%) Query: 8 QGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGF-DTYRCD--R 64 + + K++++++ +++E + I+ G+ L+ MD + V+LV + + S F D Y Sbjct: 21 EAKVFKELVDSVSKILDEGLFIITGEGLRLRGMDPARVALVDIEIPSSSFFDFYMAGDVE 80 Query: 65 NLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVE 124 + +GVN+ ++ ++ A D + +R + D + + E+ + Y + +++ V+ Sbjct: 81 RVELGVNMETLKGVVARAKKGDQLEVRVRE--DKVLFIVESVVLRR---YLLPNLEVIVD 135 Query: 125 QLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASG-ELGNGNIKLS 183 E+ + + + RD+ +GD V +D + + G E +L+ Sbjct: 136 VPEDISLEFDATATVIADVVKKTLRDVELVGDIVEFDAGEDYLSIRSVGPERRRVETRLT 195 Query: 184 QTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISD 243 + S + +E+ EP + + YL ++ ++ LS STD PL + +K D Sbjct: 196 RESPAL-----IDLEVKEPATSRYDVGYLKRMLGVAKIAESIELSFSTDKPLKMVFKSPD 250 Query: 244 MGHLKYYLAP 253 + Y LAP Sbjct: 251 GSRVTYLLAP 260 >3L0X-A nrPDB Length = 169 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 60/163 (36%), Positives = 102/163 (62%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 M EA+ + S+ K++++ KD + + G+ Q++D S V LV L + E F Y Sbjct: 7 MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEY 66 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 RCD + +G++LTS+SKIL+C N D +TL A++ D++ L+FE ++++++Y +KLMD Sbjct: 67 RCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMD 126 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCA 163 +D + L I E +Y + +PS EF++I RDLS + D++ I Sbjct: 127 IDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMIT 169 >2HII-A nrPDB Length = 257 Score = 134 bits (338), Expect = 3e-32, Method: Composition-based stats. Identities = 40/258 (15%), Positives = 103/258 (39%), Gaps = 8/258 (3%) Query: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTY 60 MF+ + ++ ++ + + + G+ + + V + + + + Y Sbjct: 1 MFKIVYPNAKDFFSFINSITNVTDSIILNFTEDGIFSRHLTEDKVLMAIMRIPKDVLSEY 60 Query: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120 D ++ ++++S+ KIL A ++ T+ + L ++ S +K Sbjct: 61 SIDSPTSVKLDVSSVKKILSKASSKKA-TIELTETDSGLKIIIRDEKSGAKSTIYIKAEK 119 Query: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180 VEQL P+ + I D++ +G+ + IS +D +K A GE G + Sbjct: 120 GQVEQLTEPKVNLAVNFTTDESVLNVIAADVTLVGEEMRISTEEDKIKIEA-GEEGKRYV 178 Query: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKA-TPLSPTVTLSMSTDVPLVVEY 239 + K++ + ++ +++ K S +S ++P+ ++ Sbjct: 179 AF-----LMKDKPLKELSIDTSASSSYSAEMFKDAVKGLRGFSAPTMVSFGENLPMKIDV 233 Query: 240 KISDMGHLKYYLAPKIED 257 + GH+ +++AP++ + Sbjct: 234 EAVSGGHMIFWIAPRLLE 251 >3L10-B nrPDB Length = 169 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 32/159 (20%), Positives = 76/159 (47%), Gaps = 3/159 (1%) Query: 100 ALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARI-CRDLSHIGDAV 158 + E + + + + + K+ D + ++ + + S + + Sbjct: 12 TITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVL 71 Query: 159 VISCAK-DGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTK 217 + + +KF A G++G+G++ + +++ E ++ +EM++PV LTF +YL K Sbjct: 72 RLRGGGGETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIK 131 Query: 218 ATPLSPTVTLSMSTDVPLVVEYKISDMGHLKYYLAPKIE 256 + LS V + +S++ P + ++ + G L+++LAPK Sbjct: 132 GSSLSDRVGIRLSSEAPALFQFDLKS-GFLQFFLAPKFN 169 >3PGE-A nrPDB Length = 200 Score = 105 bits (261), Expect = 2e-23, Method: Composition-based stats. Identities = 32/100 (32%), Positives = 61/100 (61%), Gaps = 1/100 (1%) Query: 160 ISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKAT 219 I + +KF A G++G+G++ + +++ E ++ +EM++PV LTF +YL K + Sbjct: 102 IGGGGETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGS 161 Query: 220 PLSPTVTLSMSTDVPLVVEYKISDMGHLKYYLAPKIEDEE 259 LS V + +S++ P + ++ + G L+++LAPK DEE Sbjct: 162 SLSDRVGIRLSSEAPALFQFDLKS-GFLQFFLAPKFNDEE 200 >3L0X-B nrPDB Length = 94 Score = 102 bits (255), Expect = 1e-22, Method: Composition-based stats. Identities = 31/95 (32%), Positives = 60/95 (63%), Gaps = 1/95 (1%) Query: 165 DGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPT 224 + +KF A G++G+G++ + +++ E ++ +EM++PV LTF +YL K + LS Sbjct: 1 ETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDR 60 Query: 225 VTLSMSTDVPLVVEYKISDMGHLKYYLAPKIEDEE 259 V + +S++ P + ++ + G L+++LAPK DEE Sbjct: 61 VGIRLSSEAPALFQFDLKS-GFLQFFLAPKFNDEE 94 >5W7Z-A nrPDB Length = 387 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 53 RSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVS 112 E F Y D +LA+G N + +LK + D++ L D + + + F ++ Sbjct: 323 DKESFYEYNSDESLAIGFNPQYLEDVLKAVKS-DVVELYFSDVSAPVLIKFPENPKDIFV 381 Query: 113 DYEMKL 118 +K+ Sbjct: 382 VMPVKV 387 >6D46-A nrPDB Length = 389 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 53 RSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVS 112 E F Y CD +L +G N + +LK + ++ L D + + ++ + P K Sbjct: 323 DKESFYEYNCDESLVIGFNPQYLEDVLKAVKSN-LVELYFSDISASAPVLIKFPQNPKDI 381 Query: 113 DYEMKL 118 M + Sbjct: 382 FVIMPV 387 >3A1J-A nrPDB Length = 266 Score = 35.8 bits (81), Expect = 0.017, Method: Composition-based stats. Identities = 37/239 (15%), Positives = 77/239 (32%), Gaps = 20/239 (8%) Query: 10 SILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRN---- 65 +L K + +L + +E + G++L++++SS + F Y+ Sbjct: 11 KVLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQYQAATPGQDL 70 Query: 66 LAMGVNLTSMSKI------LKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLM 119 L + + S + L+ + I+L + + L + + Sbjct: 71 LRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQL---HCKFGVRKTHNLSFQ 127 Query: 120 DLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKF--SASGELGN 177 D + Q +++ P+ S V + + S E + Sbjct: 128 DCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEVTLGIGRGRRVILRSYHEEEAD 187 Query: 178 GNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMS--TDVP 234 K T EE+ ++ E V +TF L F + + L++S D P Sbjct: 188 STAKAMVTEMCLGEEDFQQLQAQEGVAITFC---LKEFRGLLSFAESANLNLSIHFDAP 243 >6MAN-A nrPDB Length = 387 Score = 33.5 bits (75), Expect = 0.095, Method: Composition-based stats. Identities = 17/120 (14%), Positives = 46/120 (38%), Gaps = 8/120 (6%) Query: 6 LVQGSILKKVLEALKDLINE----ACWDISSGGVNLQSMDSSH---VSLVQLTLRSEGFD 58 ++ I +E + + E +S + + ++ + ++ + +E F Sbjct: 269 VINRKIFADTIERIAIITVEKFRAVKLSLSGEALEISAIGEARGNAKEVINSSKETENFY 328 Query: 59 TYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKL 118 Y + NL +G N + +LK + D++ L + + + F ++ +K+ Sbjct: 329 EYSGETNLDIGFNPQYLEDVLKAIKS-DLVELYFSSVSAPVLIKFPESPKDIFVVMPVKV 387 >5NNN-A nrPDB Length = 315 Score = 30.8 bits (68), Expect = 0.54, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 42/125 (33%), Gaps = 18/125 (14%) Query: 42 SSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLAL 101 SHV V R++ ++ + + +GV + IL+ L Sbjct: 14 KSHVLSVTQFTRADLHLLFQIAQEMRLGVQREGVLDILR---------------GKVLCT 58 Query: 102 VFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVIS 161 +F P+ + ++ + L + I + S R L++ DA+V+ Sbjct: 59 LFYEPSTRTSASFDAAMQRLGGRTIPI---QTSTSSVQKGETLQDTLRTLANYSDAIVLR 115 Query: 162 CAKDG 166 + Sbjct: 116 HPDEK 120 >4WED-A nrPDB Length = 525 Score = 28.5 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 27/56 (48%), Gaps = 8/56 (14%) Query: 32 SGGVNLQS------MDSSHVSLVQLTLR--SEGFDTYRCDRNLAMGVNLTSMSKIL 79 G L++ +D +V+LV +E + + +++G++ ++SK+L Sbjct: 254 EEGKQLEAAGFNVVVDPGNVTLVMAFNPDRAEPLKDPQVRKAVSIGIDRAAISKVL 309 >4TR8-A nrPDB Length = 383 Score = 27.7 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 19/37 (51%) Query: 63 DRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTL 99 NL +G N++ + +L G E + + ++ N+ L Sbjct: 329 GGNLEIGFNVSYLLDVLGVIGTEQVRFILSDSNSSAL 365 >3T6Z-A nrPDB Length = 495 Score = 27.3 bits (59), Expect = 6.3, Method: Composition-based stats. Identities = 6/37 (16%), Positives = 9/37 (24%) Query: 198 EMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVP 234 E + + VT+ TD P Sbjct: 410 ESASNSTSNYDDPIWRDVVSIGGVGDNVTIRFCTDNP 446 >5GAF-i nrPDB Length = 398 Score = 27.0 bits (58), Expect = 8.1, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 35 VNLQSMDSSHVSLVQLTLRSEGFDTYRCDRN----LAMGVNLTSMSKILKCAGNEDIITL 90 ++++ + + + + ++E + + DR L MG +L + L+ N+D + + Sbjct: 260 LSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILGMGFDLNDFLEQLRQMKNDDKVLV 319 Query: 91 RAE 93 R E Sbjct: 320 RME 322 >5U8T-C nrPDB Length = 194 Score = 27.0 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 6/19 (31%), Positives = 11/19 (57%) Query: 230 STDVPLVVEYKISDMGHLK 248 T+ P +Y I +G+L+ Sbjct: 13 GTEFPCKFQYDIPGLGYLE 31 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.134 0.312 Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,262,921 Number of Sequences: 36641 Number of extensions: 289107 Number of successful extensions: 941 Number of sequences better than 10.0: 44 Number of HSP's better than 10.0 without gapping: 64 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 790 Number of HSP's gapped (non-prelim): 86 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (26.9 bits)