BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P57740 (925 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5A9Q-4 nrPDB 1922 0.0 3CQC-A nrPDB 562 e-160 3CQG-A nrPDB 486 e-137 3IKO-C nrPDB 60 4e-09 1CIV-A nrPDB 31 2.0 4KSA-A nrPDB 31 2.4 2W4O-A nrPDB 31 2.5 3J2M-U nrPDB 30 3.8 3S27-A nrPDB 30 3.9 >5A9Q-4 nrPDB Length = 925 Score = 1922 bits (4979), Expect = 0.0, Method: Compositional matrix adjust. Identities = 925/925 (100%), Positives = 925/925 (100%) Query: 1 MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFR 60 MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFR Sbjct: 1 MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFR 60 Query: 61 QPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSG 120 QPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSG Sbjct: 61 QPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSG 120 Query: 121 LFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENI 180 LFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENI Sbjct: 121 LFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENI 180 Query: 181 CGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVF 240 CGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVF Sbjct: 181 CGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVF 240 Query: 241 AVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENT 300 AVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENT Sbjct: 241 AVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENT 300 Query: 301 LHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTE 360 LHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTE Sbjct: 301 LHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTE 360 Query: 361 EAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELF 420 EAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELF Sbjct: 361 EAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELF 420 Query: 421 NRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPR 480 NRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPR Sbjct: 421 NRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPR 480 Query: 481 EYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRN 540 EYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRN Sbjct: 481 EYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRN 540 Query: 541 NLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDL 600 NLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDL Sbjct: 541 NLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDL 600 Query: 601 AVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPAL 660 AVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPAL Sbjct: 601 AVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPAL 660 Query: 661 DTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSI 720 DTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSI Sbjct: 661 DTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSI 720 Query: 721 AEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQP 780 AEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQP Sbjct: 721 AEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQP 780 Query: 781 TFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDH 840 TFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDH Sbjct: 781 TFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDH 840 Query: 841 ERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKL 900 ERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKL Sbjct: 841 ERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKL 900 Query: 901 LQKLRESSLMLLDQGLDPLGYEIQL 925 LQKLRESSLMLLDQGLDPLGYEIQL Sbjct: 901 LQKLRESSLMLLDQGLDPLGYEIQL 925 >3CQC-A nrPDB Length = 270 Score = 562 bits (1449), Expect = e-160, Method: Compositional matrix adjust. Identities = 268/269 (99%), Positives = 269/269 (100%) Query: 657 APALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP 716 +PALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP Sbjct: 2 SPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP 61 Query: 717 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPAL 776 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPAL Sbjct: 62 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPAL 121 Query: 777 IPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA 836 IPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA Sbjct: 122 IPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA 181 Query: 837 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE 896 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE Sbjct: 182 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE 241 Query: 897 LRKLLQKLRESSLMLLDQGLDPLGYEIQL 925 LRKLLQKLRESSLMLLDQGLDPLGYEIQL Sbjct: 242 LRKLLQKLRESSLMLLDQGLDPLGYEIQL 270 >3CQG-A nrPDB Length = 246 Score = 486 bits (1251), Expect = e-137, Method: Compositional matrix adjust. Identities = 239/269 (88%), Positives = 240/269 (89%), Gaps = 24/269 (8%) Query: 657 APALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP 716 +PALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP Sbjct: 2 SPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP 61 Query: 717 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPAL 776 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVP Sbjct: 62 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPGGSG- 120 Query: 777 IPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA 836 G WKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA Sbjct: 121 -----------------------GSWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA 157 Query: 837 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE 896 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE Sbjct: 158 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE 217 Query: 897 LRKLLQKLRESSLMLLDQGLDPLGYEIQL 925 LRKLLQKLRESSLMLLDQGLDPLGYEIQL Sbjct: 218 LRKLLQKLRESSLMLLDQGLDPLGYEIQL 246 >3IKO-C nrPDB Length = 460 Score = 60.5 bits (145), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 70/311 (22%), Positives = 136/311 (43%), Gaps = 25/311 (8%) Query: 324 DPDAPIRQKMPLDDL-DREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWK 382 D D P+R+ + D+ D+E++ KY++ LI AG +EA K L G + Sbjct: 157 DLDFPLRENTNVLDVKDKEEDHIFFKYIYELILAGAIDEALEEAKLSDNISICMILCGIQ 216 Query: 383 LYHDPNVNG--GTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNL--KQL 438 Y +P ++ E +G +W+ + + +++ + YERAIY+ LSG + +++ Sbjct: 217 EYLNPVIDTQIANEFNTQQGIKKHSLWRRTVYSLSQQAGLDPYERAIYSYLSGAIPNQEV 276 Query: 439 LPVCDTWEDTVWAYFRVMVDSLVEQEI--QTSVATLDETEELPREYLGANWTLEKVFEEL 496 L D WE + + ++ + +E + V T + LP L L +V Sbjct: 277 LQYSD-WESDLHIHLNQILQTEIENYLLENNQVGTDELILPLPSHALTVQEVLNRV---- 331 Query: 497 QATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWL------SKSRNNL--PGHLLR 548 R E++ ++ +IL + ++ + L +++ N++ +LLR Sbjct: 332 ----ASRHPSESEHPIRVLMASVILDSLPSVIHSSVEMLLDVVKGTEASNDIIDKPYLLR 387 Query: 549 FMTHLILFFRTLGLQTKEEVS-IEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYAL 607 +THL + + + EEV +++ TYI LL + I Y L + + + Sbjct: 388 IVTHLAICLDIINPGSVEEVDKSKLITTYISLLKLQGLYENIPIYATFLNESDCLEACSF 447 Query: 608 FLESVTEFEQR 618 L S+ + + R Sbjct: 448 ILSSLEDPQVR 458 >1CIV-A nrPDB Length = 385 Score = 31.2 bits (69), Expect = 2.0, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 7/68 (10%) Query: 100 SMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTIS-AVMLREDDPGEAASMSMFSDF 158 S+VT + +W FS+ G++TN P+ I ED+ S + D E +F D+ Sbjct: 290 SLVTPTPEGDW---FST---GVYTNGNPYGIAEDIVFSMPCRSKGDGDYEFVKDVIFDDY 343 Query: 159 LQSFLKHS 166 L +K S Sbjct: 344 LSKKIKKS 351 >4KSA-A nrPDB Length = 453 Score = 31.2 bits (69), Expect = 2.4, Method: Compositional matrix adjust. Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 21/115 (18%) Query: 450 WAYF--RVMVDSLVEQEI---QTSVATLDETEELPREYLGANWTLEKVFEELQATDK--- 501 + +F R++ + L+ E+ + S A + +L RE + A+ VF + T + Sbjct: 217 YGFFHPRLVDEPLIFVEVALTKDSPAAIAPLLDLEREPIAASDATTAVFYSISNTQQGLA 276 Query: 502 ---------KRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLL 547 K+V+EE + VQ F+ L + G F+KWL + R+N LL Sbjct: 277 GISFGNFLIKQVVEEIKRELPNVQTFVTLSPVPG----FAKWLKRERDNPDSTLL 327 >2W4O-A nrPDB Length = 349 Score = 30.8 bits (68), Expect = 2.5, Method: Compositional matrix adjust. Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 6/95 (6%) Query: 565 KEEVSIEVLKTYIQLLIREKHTNLIAFYTC-HLPQDLAVAQYALFLESVTEFEQRHHCLE 623 K+ V ++++T I +L+R H N+I P ++ +L LE VT E +E Sbjct: 87 KKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEI-----SLVLELVTGGELFDRIVE 141 Query: 624 LAKEADLDVATITKTVVENIRKKDNGEFSHHDLAP 658 ++ D A K ++E + H DL P Sbjct: 142 KGYYSERDAADAVKQILEAVAYLHENGIVHRDLKP 176 >3J2M-U nrPDB Length = 659 Score = 30.4 bits (67), Expect = 3.8, Method: Compositional matrix adjust. Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 15/102 (14%) Query: 108 SNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSS 167 SNW A SS SGL ++ + +T S ++L E + EAA ++ DF + K+ Sbjct: 165 SNWTAEISSSSSGL---AAVITLGKIITDSGILLAEIENAEAAMTAV--DFQANLKKYGI 219 Query: 168 STVFDLVEEYENICGSQVNILSKIVSRATPGLQKFSKTASML 209 V L Y G ++ I +IVS+A ++K AS L Sbjct: 220 PGVVAL---YPGELGDKIEI--EIVSKA-----DYAKGASAL 251 >3S27-A nrPDB Length = 816 Score = 30.4 bits (67), Expect = 3.9, Method: Compositional matrix adjust. Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 449 VWAYFRVMVDSLVEQEIQTSVATLDETEELPREYLGANWTLEKVFEELQAT 499 VW Y RV + +LV +E+Q + L EEL N+TLE FE A+ Sbjct: 96 VWEYLRVNLHALVVEELQPA-EFLHFKEELVDGVKNGNFTLELDFEPFNAS 145 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5A9Q-4 nrPDB 1776 0.0 3CQC-A nrPDB 556 e-158 3CQG-A nrPDB 503 e-142 3IKO-C nrPDB 411 e-115 Sequences not found previously or not previously below threshold: 2X4F-A nrPDB 34 0.30 2W4O-A nrPDB 33 0.57 3LIJ-A nrPDB 32 0.86 4LGV-A nrPDB 32 0.90 1MHZ-B nrPDB 32 1.1 3J2M-U nrPDB 32 1.8 1CIV-A nrPDB 31 2.8 5HAX-A nrPDB 30 3.6 5HB1-A nrPDB 30 4.3 5JN2-A nrPDB 30 6.5 3MA6-A nrPDB 30 6.5 CONVERGED! >5A9Q-4 nrPDB Length = 925 Score = 1776 bits (4601), Expect = 0.0, Method: Composition-based stats. Identities = 925/925 (100%), Positives = 925/925 (100%) Query: 1 MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFR 60 MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFR Sbjct: 1 MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFR 60 Query: 61 QPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSG 120 QPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSG Sbjct: 61 QPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSG 120 Query: 121 LFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENI 180 LFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENI Sbjct: 121 LFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENI 180 Query: 181 CGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVF 240 CGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVF Sbjct: 181 CGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVF 240 Query: 241 AVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENT 300 AVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENT Sbjct: 241 AVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENT 300 Query: 301 LHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTE 360 LHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTE Sbjct: 301 LHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTE 360 Query: 361 EAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELF 420 EAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELF Sbjct: 361 EAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELF 420 Query: 421 NRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPR 480 NRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPR Sbjct: 421 NRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPR 480 Query: 481 EYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRN 540 EYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRN Sbjct: 481 EYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRN 540 Query: 541 NLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDL 600 NLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDL Sbjct: 541 NLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDL 600 Query: 601 AVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPAL 660 AVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPAL Sbjct: 601 AVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPAL 660 Query: 661 DTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSI 720 DTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSI Sbjct: 661 DTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSI 720 Query: 721 AEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQP 780 AEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQP Sbjct: 721 AEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQP 780 Query: 781 TFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDH 840 TFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDH Sbjct: 781 TFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDH 840 Query: 841 ERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKL 900 ERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKL Sbjct: 841 ERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKL 900 Query: 901 LQKLRESSLMLLDQGLDPLGYEIQL 925 LQKLRESSLMLLDQGLDPLGYEIQL Sbjct: 901 LQKLRESSLMLLDQGLDPLGYEIQL 925 >3CQC-A nrPDB Length = 270 Score = 556 bits (1434), Expect = e-158, Method: Composition-based stats. Identities = 268/269 (99%), Positives = 269/269 (100%) Query: 657 APALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP 716 +PALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP Sbjct: 2 SPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP 61 Query: 717 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPAL 776 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPAL Sbjct: 62 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPAL 121 Query: 777 IPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA 836 IPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA Sbjct: 122 IPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA 181 Query: 837 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE 896 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE Sbjct: 182 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE 241 Query: 897 LRKLLQKLRESSLMLLDQGLDPLGYEIQL 925 LRKLLQKLRESSLMLLDQGLDPLGYEIQL Sbjct: 242 LRKLLQKLRESSLMLLDQGLDPLGYEIQL 270 >3CQG-A nrPDB Length = 246 Score = 503 bits (1296), Expect = e-142, Method: Composition-based stats. Identities = 239/269 (88%), Positives = 240/269 (89%), Gaps = 24/269 (8%) Query: 657 APALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP 716 +PALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP Sbjct: 2 SPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIP 61 Query: 717 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPAL 776 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVP Sbjct: 62 QDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPGGSG- 120 Query: 777 IPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA 836 G WKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA Sbjct: 121 -----------------------GSWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDA 157 Query: 837 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE 896 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE Sbjct: 158 KEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEE 217 Query: 897 LRKLLQKLRESSLMLLDQGLDPLGYEIQL 925 LRKLLQKLRESSLMLLDQGLDPLGYEIQL Sbjct: 218 LRKLLQKLRESSLMLLDQGLDPLGYEIQL 246 >3IKO-C nrPDB Length = 460 Score = 411 bits (1056), Expect = e-115, Method: Composition-based stats. Identities = 70/311 (22%), Positives = 136/311 (43%), Gaps = 25/311 (8%) Query: 324 DPDAPIRQKMPLDDL-DREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWK 382 D D P+R+ + D+ D+E++ KY++ LI AG +EA K L G + Sbjct: 157 DLDFPLRENTNVLDVKDKEEDHIFFKYIYELILAGAIDEALEEAKLSDNISICMILCGIQ 216 Query: 383 LYHDPNVNG--GTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNL--KQL 438 Y +P ++ E +G +W+ + + +++ + YERAIY+ LSG + +++ Sbjct: 217 EYLNPVIDTQIANEFNTQQGIKKHSLWRRTVYSLSQQAGLDPYERAIYSYLSGAIPNQEV 276 Query: 439 LPVCDTWEDTVWAYFRVMVDSLVEQEI--QTSVATLDETEELPREYLGANWTLEKVFEEL 496 L D WE + + ++ + +E + V T + LP L L +V Sbjct: 277 LQYSD-WESDLHIHLNQILQTEIENYLLENNQVGTDELILPLPSHALTVQEVLNRV---- 331 Query: 497 QATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWL------SKSRNNL--PGHLLR 548 R E++ ++ +IL + ++ + L +++ N++ +LLR Sbjct: 332 ----ASRHPSESEHPIRVLMASVILDSLPSVIHSSVEMLLDVVKGTEASNDIIDKPYLLR 387 Query: 549 FMTHLILFFRTLGLQTKEEVS-IEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYAL 607 +THL + + + EEV +++ TYI LL + I Y L + + + Sbjct: 388 IVTHLAICLDIINPGSVEEVDKSKLITTYISLLKLQGLYENIPIYATFLNESDCLEACSF 447 Query: 608 FLESVTEFEQR 618 L S+ + + R Sbjct: 448 ILSSLEDPQVR 458 >2X4F-A nrPDB Length = 373 Score = 33.9 bits (76), Expect = 0.30, Method: Composition-based stats. Identities = 44/163 (26%), Positives = 65/163 (39%), Gaps = 15/163 (9%) Query: 557 FRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFE 616 +T G++ KEEV E I ++ + H NLI Y ++ V L +E V E Sbjct: 122 IKTRGMKDKEEVKNE-----ISVMNQLDHANLIQLYDAFESKNDIV----LVMEYVDGGE 172 Query: 617 QRHHCLELAKE-ADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVI 675 ++ + +LD K + E IR H DL P + D +I +I Sbjct: 173 LFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLKPE-NILCVNRDAKQIKII 231 Query: 676 DWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQD 718 D+ + + E LK N +FLA E FV P D Sbjct: 232 DFGLARRYKPREKLKV-NFGTPEFLAP---EVVNYDFVSFPTD 270 >2W4O-A nrPDB Length = 349 Score = 33.1 bits (74), Expect = 0.57, Method: Composition-based stats. Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 4/94 (4%) Query: 565 KEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLEL 624 K+ V ++++T I +L+R H N+I + +L LE VT E +E Sbjct: 87 KKTVDKKIVRTEIGVLLRLSHPNIIKLKEIF----ETPTEISLVLELVTGGELFDRIVEK 142 Query: 625 AKEADLDVATITKTVVENIRKKDNGEFSHHDLAP 658 ++ D A K ++E + H DL P Sbjct: 143 GYYSERDAADAVKQILEAVAYLHENGIVHRDLKP 176 >3LIJ-A nrPDB Length = 494 Score = 32.4 bits (72), Expect = 0.86, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 49/129 (37%), Gaps = 6/129 (4%) Query: 550 MTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFL 609 +TH+ + + + S L + +L H N++ Y + Y L + Sbjct: 60 VTHVERAIKIIRKTSVSTSSNSKLLEEVAVLKLLDHPNIMKLYDFFEDK----RNYYLVM 115 Query: 610 ESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPA-LDTGTTEED 668 E E + K ++D A I K V+ + H DL P L + E+D Sbjct: 116 ECYKGGELFDEIIHRMKFNEVDAAVIIKQVLSGVTYLHKHNIVHRDLKPENLLLESKEKD 175 Query: 669 RLKIDVIDW 677 L I ++D+ Sbjct: 176 AL-IKIVDF 183 >4LGV-A nrPDB Length = 490 Score = 32.4 bits (72), Expect = 0.90, Method: Composition-based stats. Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 4/92 (4%) Query: 381 WKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLP 440 L DP+ +L G+ + + S + + E YER +YAA +G+ +QL Sbjct: 374 IVLRIDPDPGMRLQLSAQVGDSWHDVHLDSSFAVDLGEPVRPYERLLYAAFNGD-RQLFA 432 Query: 441 VCDTWEDTVWAYFRVMVD--SLVEQEIQTSVA 470 D E+T W + ++D S + Q Q S Sbjct: 433 REDAIEET-WRIVQPVLDKPSRIHQYEQGSWG 463 >1MHZ-B nrPDB Length = 395 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 37/104 (35%), Gaps = 9/104 (8%) Query: 410 SCWRMAEDELFNRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSV 469 + + F + + G + L C + A+ R +++ E + +SV Sbjct: 273 TVYGDTLTPFFTAQSQTYFQTTRGAIDDLFVYCLANDSEFGAHNRTFLNAWTEHYLASSV 332 Query: 470 ATLDETEEL---------PREYLGANWTLEKVFEELQATDKKRV 504 A L + L + G + L++VF + + ++ Sbjct: 333 AALKDFVGLYAKVEKVAGATDSAGVSEALQRVFGDWKIDYADKI 376 >3J2M-U nrPDB Length = 659 Score = 31.6 bits (70), Expect = 1.8, Method: Composition-based stats. Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 15/102 (14%) Query: 108 SNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSS 167 SNW A SS SGL ++ + +T S ++L E + EAA ++ DF + K+ Sbjct: 165 SNWTAEISSSSSGLAAVI---TLGKIITDSGILLAEIENAEAAMTAV--DFQANLKKYGI 219 Query: 168 STVFDLVEEYENICGSQVNILSKIVSRATPGLQKFSKTASML 209 V L Y G ++ I +IVS+A ++K AS L Sbjct: 220 PGVVAL---YPGELGDKIEI--EIVSKA-----DYAKGASAL 251 >1CIV-A nrPDB Length = 385 Score = 30.8 bits (68), Expect = 2.8, Method: Composition-based stats. Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 7/68 (10%) Query: 100 SMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTIS-AVMLREDDPGEAASMSMFSDF 158 S+VT + +W FS+ G++TN P+ I ED+ S + D E +F D+ Sbjct: 290 SLVTPTPEGDW---FST---GVYTNGNPYGIAEDIVFSMPCRSKGDGDYEFVKDVIFDDY 343 Query: 159 LQSFLKHS 166 L +K S Sbjct: 344 LSKKIKKS 351 >5HAX-A nrPDB Length = 742 Score = 30.4 bits (67), Expect = 3.6, Method: Composition-based stats. Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 7/108 (6%) Query: 159 LQSFLKHSSSTVFDLVEEYENICGSQVNILSKIVSRATPGLQKF----SKTASMLWLLQQ 214 L++FL+ + ST+ L E + G Q +I ++ +A LQK S+ S + +L Sbjct: 635 LRNFLEANKSTIQGLAPPSERLFGRQEDIANQKEHQALHALQKLMESISEGISFVLMLFD 694 Query: 215 EMVT--WRLLASLYRDRIQSALEEESVFAVTAVNASEKTVVEALFQRD 260 E V+ + L ++ + +++ L E +F+ T K +V+A+ R+ Sbjct: 695 ERVSDIYARLDAVSQQQLKD-LTYEQLFSQTPGKELAKVLVKAIVNRN 741 >5HB1-A nrPDB Length = 830 Score = 30.0 bits (66), Expect = 4.3, Method: Composition-based stats. Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 7/108 (6%) Query: 159 LQSFLKHSSSTVFDLVEEYENICGSQVNILSKIVSRATPGLQKF----SKTASMLWLLQQ 214 L++FL+ + ST+ L E + G Q +I ++ +A LQK S+ S + +L Sbjct: 147 LRNFLEANKSTIQGLAPPSERLFGRQEDIANQKEHQALHALQKLMESISEGISFVLMLFD 206 Query: 215 EMVT--WRLLASLYRDRIQSALEEESVFAVTAVNASEKTVVEALFQRD 260 E V+ + L ++ + +++ L E +F+ T K +V+A+ R+ Sbjct: 207 ERVSDIYARLDAVSQQQLKD-LTYEQLFSQTPGKELAKVLVKAIVNRN 253 >5JN2-A nrPDB Length = 525 Score = 29.7 bits (65), Expect = 6.5, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 46/115 (40%), Gaps = 4/115 (3%) Query: 563 QTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCL 622 Q K++ E L +QLL + H N++ Y + + L E T E + Sbjct: 104 QVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKG----YFYLVGEVYTGGELFDEII 159 Query: 623 ELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDW 677 + +++D A I + V+ I + H DL P ++ I +ID+ Sbjct: 160 SRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDF 214 >3MA6-A nrPDB Length = 298 Score = 29.7 bits (65), Expect = 6.5, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 46/115 (40%), Gaps = 4/115 (3%) Query: 563 QTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCL 622 Q K++ E L +QLL + H N++ Y + + L E T E + Sbjct: 69 QVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKG----YFYLVGEVYTGGELFDEII 124 Query: 623 ELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDW 677 + +++D A I + V+ I + H DL P ++ I +ID+ Sbjct: 125 SRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDF 179 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.316 0.133 0.376 Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,533,243 Number of Sequences: 36641 Number of extensions: 1519968 Number of successful extensions: 4022 Number of sequences better than 10.0: 19 Number of HSP's better than 10.0 without gapping: 8 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 4000 Number of HSP's gapped (non-prelim): 40 length of query: 925 length of database: 10,336,785 effective HSP length: 106 effective length of query: 819 effective length of database: 6,452,839 effective search space: 5284875141 effective search space used: 5284875141 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.3 bits)