BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P56536 (239 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3X2T-A nrPDB 499 e-142 2KIN-A nrPDB 494 e-140 5HNZ-K nrPDB 473 e-134 4UXT-C nrPDB 451 e-127 3J8Y-K nrPDB 429 e-121 2Y5W-A nrPDB 366 e-102 1GOJ-A nrPDB 233 6e-62 4UXR-C nrPDB 165 1e-41 3ZFC-A nrPDB 162 2e-40 3B6U-A nrPDB 159 1e-39 2VVG-A nrPDB 156 6e-39 1T5C-A nrPDB 155 1e-38 5GSZ-A nrPDB 148 2e-36 3B6V-A nrPDB 146 9e-36 6A1Z-A nrPDB 145 2e-35 2XT3-A nrPDB 142 1e-34 3GBJ-A nrPDB 142 1e-34 2WBE-C nrPDB 141 3e-34 3WPN-A nrPDB 141 3e-34 3H4S-A nrPDB 140 4e-34 4BN2-A nrPDB 140 6e-34 3CNZ-A nrPDB 139 1e-33 2OWM-A nrPDB 137 4e-33 5WDE-A nrPDB 134 3e-32 4OZQ-A nrPDB 132 2e-31 5OAM-K nrPDB 128 2e-30 5M5O-C nrPDB 125 1e-29 6NJE-A nrPDB 125 2e-29 5MLV-G nrPDB 124 3e-29 5WDH-A nrPDB 123 7e-29 2GRY-A nrPDB 122 9e-29 3T0Q-A nrPDB 122 1e-28 5MM7-K nrPDB 122 1e-28 5MM4-K nrPDB 122 1e-28 5W3D-A nrPDB 122 2e-28 3NWN-A nrPDB 121 2e-28 3EDL-D nrPDB 119 1e-27 5XJA-A nrPDB 119 2e-27 3J2U-K nrPDB 118 2e-27 4UBF-A nrPDB 118 2e-27 5MIO-C nrPDB 117 6e-27 6B0I-K nrPDB 114 4e-26 4GKR-A nrPDB 112 1e-25 3DC4-A nrPDB 107 6e-24 4H1G-A nrPDB 103 4e-23 1F9T-A nrPDB 100 6e-22 1RY6-A nrPDB 100 1e-21 4ETP-A nrPDB 99 1e-21 5X3E-A nrPDB 90 9e-19 5ND7-C nrPDB 72 2e-13 5ZFQ-A nrPDB 36 0.016 5MUU-C nrPDB 31 0.40 4KT7-A nrPDB 31 0.43 3R8F-A nrPDB 31 0.57 2YW2-A nrPDB 30 1.2 1FOB-A nrPDB 29 1.8 1DDZ-A nrPDB 28 2.8 5A5T-C nrPDB 28 2.8 1G6H-A nrPDB 28 4.2 3J8B-C nrPDB 27 9.1 >3X2T-A nrPDB Length = 341 Score = 499 bits (1286), Expect = e-142, Method: Compositional matrix adjust. Identities = 239/239 (100%), Positives = 239/239 (100%) Query: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQE 60 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQE Sbjct: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQE 60 Query: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI Sbjct: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120 Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV Sbjct: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180 Query: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV Sbjct: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 >2KIN-A nrPDB Length = 238 Score = 494 bits (1273), Expect = e-140, Method: Compositional matrix adjust. Identities = 238/238 (100%), Positives = 238/238 (100%) Query: 2 ADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQ 61 ADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQ Sbjct: 1 ADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQ 60 Query: 62 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY 121 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY Sbjct: 61 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY 120 Query: 122 SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 181 SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVM Sbjct: 121 SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 180 Query: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV Sbjct: 181 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 238 >5HNZ-K nrPDB Length = 371 Score = 473 bits (1217), Expect = e-134, Method: Compositional matrix adjust. Identities = 228/232 (98%), Positives = 230/232 (99%), Gaps = 1/232 (0%) Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACA 67 +IKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI QGKPYVFDRVLPPNTTQEQVYNACA Sbjct: 24 NIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI-QGKPYVFDRVLPPNTTQEQVYNACA 82 Query: 68 KQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENL 127 KQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENL Sbjct: 83 KQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENL 142 Query: 128 EFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEG 187 EF IKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEG Sbjct: 143 EFAIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEG 202 Query: 188 KANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 K+NRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV Sbjct: 203 KSNRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 254 >4UXT-C nrPDB Length = 340 Score = 451 bits (1159), Expect = e-127, Method: Compositional matrix adjust. Identities = 212/234 (90%), Positives = 228/234 (97%), Gaps = 1/234 (0%) Query: 6 ECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNA 65 ECSIKV+CRFRPLN+AEILRGDKFIP F+G+++VVIG GKPYVFDRV PPNTTQEQVY+A Sbjct: 7 ECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVYHA 65 Query: 66 CAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDE 125 CA QIVKDVL GYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA DIF+HIYSMDE Sbjct: 66 CAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDE 125 Query: 126 NLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVID 185 NLEFHIKVSYFEIYLDKIRDLLDV+KTNL+VHEDKNRVP+VKGCTERFVSSPEE++DVID Sbjct: 126 NLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVID 185 Query: 186 EGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 EGK+NRHVAVTNMNEHSSRSHSIFLINIKQEN+ETE+KLSGKLYLVDLAGSEKV Sbjct: 186 EGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKV 239 >3J8Y-K nrPDB Length = 349 Score = 429 bits (1102), Expect = e-121, Method: Compositional matrix adjust. Identities = 203/239 (84%), Positives = 221/239 (92%), Gaps = 1/239 (0%) Query: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQE 60 MAD AE +IKVMCRFRPLNE+E+ RGDK+I KF+GE+TVVI KPY FDRV +T+QE Sbjct: 1 MADLAESNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIAS-KPYAFDRVFQSSTSQE 59 Query: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120 QVYN CAK+IVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP+ MGIIPRI DIF++I Sbjct: 60 QVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYI 119 Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNL+VHEDKNRVPYVKG TERFVSSP+EV Sbjct: 120 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEV 179 Query: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 MD IDEGK+NRHVAVTNMNEHSSRSHSIFLIN+KQEN +TE+KLSGKLYLVDLAGSEKV Sbjct: 180 MDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKV 238 >2Y5W-A nrPDB Length = 365 Score = 366 bits (940), Expect = e-102, Method: Compositional matrix adjust. Identities = 176/238 (73%), Positives = 202/238 (84%), Gaps = 2/238 (0%) Query: 4 PAECSIKVMCRFRPLNEAEILRGDKFIPKFKG--EETVVIGQGKPYVFDRVLPPNTTQEQ 61 PAE SIKV+CRFRPLN++E G KF+ KF EE + GK Y+FD+V PN +QE+ Sbjct: 8 PAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFDKVFKPNASQEK 67 Query: 62 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY 121 VYN AK IV DVL GYNGTIFAYGQTSSGKTHTMEG + D GIIPRI +DIF+HIY Sbjct: 68 VYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIY 127 Query: 122 SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 181 +M+ NLEFHIKVSY+EIY+DKIRDLLDVSK NL+VHEDKNRVPYVKG TERFVSSPE+V Sbjct: 128 AMEVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVF 187 Query: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 +VI+EGK+NRH+AVTNMNEHSSRSHS+FLIN+KQEN+E +KKLSGKLYLVDLAGSEKV Sbjct: 188 EVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKV 245 >1GOJ-A nrPDB Length = 355 Score = 233 bits (593), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 122/237 (51%), Positives = 156/237 (65%), Gaps = 6/237 (2%) Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI----GQGKPYVFDRVLPPNTTQEQVY 63 SIKV+ RFRP N EI G + I F+G +T + QG + FDRV + Q ++ Sbjct: 7 SIKVVARFRPQNRVEIESGGQPIVTFQGPDTCTVDSKEAQGS-FTFDRVFDMSCKQSDIF 65 Query: 64 NACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEG-KLHDPQLMGIIPRIAHDIFDHIYS 122 + K V D+L GYNGT+FAYGQT +GK++TM G + DP G+IPRI IF I S Sbjct: 66 DFSIKPTVDDILNGYNGTVFAYGQTGAGKSYTMMGTSIDDPDGRGVIPRIVEQIFTSILS 125 Query: 123 MDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMD 182 N+E+ ++VSY EIY+++IRDLL NL VHE+KNR YVKG E +VSS +EV + Sbjct: 126 SAANIEYTVRVSYMEIYMERIRDLLAPQNDNLPVHEEKNRGVYVKGLLEIYVSSVQEVYE 185 Query: 183 VIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 V+ G R VA TNMN+ SSRSHSIF+I I Q+NVET SG+L+LVDLAGSEKV Sbjct: 186 VMRRGGNARAVAATNMNQESSRSHSIFVITITQKNVETGSAKSGQLFLVDLAGSEKV 242 >4UXR-C nrPDB Length = 375 Score = 165 bits (418), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 101/257 (39%), Positives = 146/257 (56%), Gaps = 25/257 (9%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKP------YVFDRVLPPNTT 58 A S+KV R RP N E+ R K I + G T ++ +P + FD +T+ Sbjct: 8 AGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTS 67 Query: 59 QEQVYNACAKQIVKDV--------LEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIP 110 E + A KQ+ +D+ EGYN IFAYGQT +GK++TM GK Q GIIP Sbjct: 68 PEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQ-QGIIP 126 Query: 111 RIAHDIFDHIY-SMDENLEFHIKVSYFEIYLDKIRDLLD-VSKTNLAVHEDKNRVPYVKG 168 ++ D+F I + ++N+ + ++VSY EIY +++RDLL+ +K NL V E PYV+ Sbjct: 127 QLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVED 186 Query: 169 CTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE------NVETEK 222 ++ V+S ++ D++D G R VA TNMNE SSRSH++F I Q+ N+ TEK Sbjct: 187 LSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEK 246 Query: 223 KLSGKLYLVDLAGSEKV 239 K+ LVDLAGSE+ Sbjct: 247 --VSKISLVDLAGSERA 261 >3ZFC-A nrPDB Length = 350 Score = 162 bits (409), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 96/242 (39%), Positives = 139/242 (57%), Gaps = 16/242 (6%) Query: 9 IKVMCRFRPLNEAEILRGDK----FIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYN 64 ++V R RPL EI G + F+P GE VV+G K + +D V P+T QE+V+N Sbjct: 10 VRVALRCRPLVSKEIKEGCQTCLSFVP---GEPQVVVGNDKSFTYDFVFDPSTEQEEVFN 66 Query: 65 ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ----LMGIIPRIAHDIFDHI 120 ++K V +GYN T+ AYGQT SGKT++M G Q +G+IPR+ +F I Sbjct: 67 TAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEHDSAIGVIPRVIQLLFKEI 126 Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSK---TNLAVHEDKNRVPYVKGCTERFVSSP 177 + + EF +KVSY EIY ++I DLL S+ T + + ED + G TE+ V Sbjct: 127 -NKKSDFEFTLKVSYLEIYNEEILDLLCSSREKATQINIREDPKEGIKIVGLTEKTVLVA 185 Query: 178 EEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ-ENVETEKKLSGKLYLVDLAGS 236 + + +++G +R VA T MN SSRSH+IF I+I+Q + + KL+LVDLAGS Sbjct: 186 SDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGS 245 Query: 237 EK 238 E+ Sbjct: 246 ER 247 >3B6U-A nrPDB Length = 372 Score = 159 bits (402), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 103/245 (42%), Positives = 144/245 (58%), Gaps = 16/245 (6%) Query: 8 SIKVMCRFRPLNEAEILRG-DKFIP---KFKGEETVVIGQG------KPYVFDRVLPPNT 57 S++V+ R RP+N E DK + K G+ +V +G K + FD V N Sbjct: 22 SVRVVVRCRPMNGKEKAASYDKVVDVDVKL-GQVSVKNPKGTAHEMPKTFTFDAVYDWNA 80 Query: 58 TQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIF 117 Q ++Y+ + +V VL+G+NGTIFAYGQT +GKT+TMEG DP+ G+IP IF Sbjct: 81 KQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDHIF 140 Query: 118 DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKT-NLAVHEDKNRVPYVKGCTERFVSS 176 HI S +N ++ ++ SY EIY ++IRDLL +T L + E + YVK + S Sbjct: 141 THI-SRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKS 199 Query: 177 PEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENV--ETEKKLS-GKLYLVDL 233 +E+ V++ G NR V TNMNEHSSRSH+IF+I I+ V + E + GKL LVDL Sbjct: 200 VKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDL 259 Query: 234 AGSEK 238 AGSE+ Sbjct: 260 AGSER 264 >2VVG-A nrPDB Length = 350 Score = 156 bits (395), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 100/247 (40%), Positives = 138/247 (55%), Gaps = 20/247 (8%) Query: 8 SIKVMCRFRPLNEAE-------ILRGDKFI-------PKFKGEETVVIGQGKPYVFDRVL 53 +IKV+ R RPLN E I+R D+ P+ + T + + FD V Sbjct: 5 NIKVIVRCRPLNARETRENALNIIRMDEASAQVIVDPPEQEKSATQAKKVPRTFTFDAVY 64 Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113 + ++ A K ++ VLEG+N TIFAYGQT +GKT TM G +P G IP Sbjct: 65 DQTSCNYGIFQASFKPLIDAVLEGFNSTIFAYGQTGAGKTWTMGGNKEEP---GAIPNSF 121 Query: 114 HDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERF 173 +FD I S N F + SY E+Y ++IRDL+ + T L + EDK R YV G + Sbjct: 122 KHLFDAINSSSSNQNFLVIGSYLELYNEEIRDLIK-NNTKLPLKEDKTRGIYVDGLSMHR 180 Query: 174 VSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKL--SGKLYLV 231 V++ E+ ++D+G ANRHVA T MN+ SSRSHSIF++ I+ V K++ GKL LV Sbjct: 181 VTTAAELSALMDKGFANRHVAATQMNDTSSRSHSIFMVRIECSEVIENKEVIRVGKLNLV 240 Query: 232 DLAGSEK 238 DLAGSE+ Sbjct: 241 DLAGSER 247 >1T5C-A nrPDB Length = 349 Score = 155 bits (392), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 100/244 (40%), Positives = 135/244 (55%), Gaps = 15/244 (6%) Query: 6 ECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVV--IGQGKPYVFDRVLPPNTTQEQVY 63 E ++ V R RPLN E G+ +K + V+ + K + FDRV N T + VY Sbjct: 3 EGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNVY 62 Query: 64 NACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSM 123 A I+ ++GYNGTIFAYGQT+SGKT+TM G +G+IPR HDIF I Sbjct: 63 EEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMG---SEDHLGVIPRAIHDIFQKIKKF 119 Query: 124 DENLEFHIKVSYFEIYLDKIRDLLDVSKTN--LAVHEDKNRVPYVKGCTERFVSSPEEVM 181 + EF ++VSY EIY + I DLL ++ L + ED NR YV TE V + E + Sbjct: 120 PDR-EFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMAL 178 Query: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE------NVETEKKLSGKLYLVDLAG 235 I +G+ +RH T MN+ SSRSH+IF + ++ N E K+S L LVDLAG Sbjct: 179 KWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVS-HLNLVDLAG 237 Query: 236 SEKV 239 SE+ Sbjct: 238 SERA 241 >5GSZ-A nrPDB Length = 353 Score = 148 bits (374), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 88/257 (34%), Positives = 135/257 (52%), Gaps = 23/257 (8%) Query: 2 ADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI---------------GQGKP 46 D + + V R RP++ AE+ G I E+ VV+ + K Sbjct: 5 GDSKDQQLMVALRVRPISVAELEEGATLIAHKMDEQMVVLMDPMEDPDDILRAHRSREKS 64 Query: 47 YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106 Y+FD TQE VY A K +++ V+ GYN T+FAYG T GKT+TM G H+P Sbjct: 65 YLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEP--- 121 Query: 107 GIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYV 166 GI R +D+F I ++E+ + +SY EIY + IRDLL+ + L + ED V V Sbjct: 122 GIYVRTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPALGYLELREDSKGVIQV 181 Query: 167 KGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ----ENVETEK 222 G TE + +E+M ++ +G R T N+ SSRSH++ + ++Q +N+ E Sbjct: 182 AGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVKNILQEV 241 Query: 223 KLSGKLYLVDLAGSEKV 239 + G+L+++DLAGSE+ Sbjct: 242 R-QGRLFMIDLAGSERA 257 >3B6V-A nrPDB Length = 395 Score = 146 bits (368), Expect = 9e-36, Method: Compositional matrix adjust. Identities = 89/247 (36%), Positives = 139/247 (56%), Gaps = 14/247 (5%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFK---GEETVVIGQGKP------YVFDRVLPP 55 A ++KV+ R RPL+ E G + I G+ T+ + P + FD V Sbjct: 19 ASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDA 78 Query: 56 NTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHD 115 ++ Q +Y+ + ++ VL+G+NGT+FAYGQT +GKT+TM+G +P+L G+IP Sbjct: 79 SSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEH 138 Query: 116 IFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSK-TNLAVHEDKNRVPYVKGCTERFV 174 IF HI S +N ++ ++ SY EIY ++IRDLL L + E+ Y+K + Sbjct: 139 IFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVT 197 Query: 175 SSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK---LSGKLYLV 231 + +E+ V++ G R V T+MNE SSRSH+IF+I ++ ++ + GKL LV Sbjct: 198 KNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLV 257 Query: 232 DLAGSEK 238 DLAGSE+ Sbjct: 258 DLAGSER 264 >6A1Z-A nrPDB Length = 395 Score = 145 bits (365), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 93/263 (35%), Positives = 139/263 (52%), Gaps = 32/263 (12%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI----------GQGKPYVF----- 49 + +KV R RP+N EI K + + + ++ +G+P +F Sbjct: 2 GDSKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPINTNLSKGDARGQPKIFAYDHC 61 Query: 50 -----DRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ 104 + V Q+ V+ + I+++ +GYN IFAYGQT SGK++TM G P Sbjct: 62 FWSMDESVREKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP- 120 Query: 105 LMGIIPRIAHDIFDHIYSMDENLE--FHIKVSYFEIYLDKIRDLLD--VSKTNLAVHEDK 160 G+IPR+ +F+ +EN E F ++VSY EIY +K+RDLLD S+ L V E Sbjct: 121 --GLIPRLCSGLFERT-QKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHS 177 Query: 161 NRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVET 220 PYV G ++ V+S +++ ++ EG +R VA TNMNE SSRSH++F I + + Sbjct: 178 VLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDV 237 Query: 221 EKKLS----GKLYLVDLAGSEKV 239 + S GKL LVDLAGSE+ Sbjct: 238 KSGTSGEKVGKLSLVDLAGSERA 260 >2XT3-A nrPDB Length = 344 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 91/252 (36%), Positives = 137/252 (54%), Gaps = 23/252 (9%) Query: 6 ECSIKVMCRFRPLNEAEILRGDKFIPKFK-GEETVVIGQGKPYVFDRVLPPNTTQEQVYN 64 E ++V R RPL E+L G + + + G V +G+ + + F VL + QE VY Sbjct: 10 EAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQ 69 Query: 65 ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTM-----EGKLHDPQLMGIIPRIAHDIFDH 119 AC + +++ EG+N T+FAYGQT SGKT+TM L D Q GI+PR + F Sbjct: 70 ACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQ--GIVPRAMAEAFKL 127 Query: 120 IYSMDEN--LEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNRVPYVKGCTERFVS 175 I DEN L+ + VSY E+Y ++ RDLL+V + ++ + ED+ + G E V Sbjct: 128 I---DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVE 184 Query: 176 SPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEK--------KLSGK 227 +EV+ +++ G A RH T++N SSRSH++F + +KQ + L K Sbjct: 185 GLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLKQRGRAPSRLPRPAPGQLLVSK 244 Query: 228 LYLVDLAGSEKV 239 + VDLAGSE+V Sbjct: 245 FHFVDLAGSERV 256 >3GBJ-A nrPDB Length = 354 Score = 142 bits (358), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 93/259 (35%), Positives = 136/259 (52%), Gaps = 32/259 (12%) Query: 9 IKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI----------GQGKPYVF--------- 49 +KV R RP+N E K + + ++ +G+P VF Sbjct: 3 VKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCFWSM 62 Query: 50 -DRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGI 108 + V Q+ V+ + I+++ +GYN IFAYGQT SGK++TM G P G+ Sbjct: 63 DESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP---GL 119 Query: 109 IPRIAHDIFDHIYSMDENLE--FHIKVSYFEIYLDKIRDLLD--VSKTNLAVHEDKNRVP 164 IPR+ +F+ +EN E F ++VSY EIY +K+RDLLD S+ L V E P Sbjct: 120 IPRLCSGLFERT-QKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGP 178 Query: 165 YVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKL 224 YV G ++ V+S +++ ++ EG +R VA TNMNE SSRSH++F I + + + Sbjct: 179 YVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGT 238 Query: 225 S----GKLYLVDLAGSEKV 239 S GKL LVDLAGSE+ Sbjct: 239 SGEKVGKLSLVDLAGSERA 257 >2WBE-C nrPDB Length = 373 Score = 141 bits (355), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 92/252 (36%), Positives = 135/252 (53%), Gaps = 22/252 (8%) Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQG------KPYVFDRVLPPNTTQEQ 61 +I+V R RPLN E + G VV K + FDR P + Q Sbjct: 24 NIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDSKLTKKFTFDRSFGPESKQCD 83 Query: 62 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEG--------KLHDPQLMGIIPRIA 113 VY+ ++++VL GYN T+FAYGQT +GKTHTM G D +GIIPR Sbjct: 84 VYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIPRAL 143 Query: 114 HDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLL---DVSKTNLAVHEDKNRVPYVKGCT 170 +FD + M+ +E+ +++SY E+Y +++ DLL D +K + K ++G Sbjct: 144 SHLFDELRMME--VEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDSTKKGSVIIQGLE 201 Query: 171 ERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIF--LINIKQENVETEKKLS-GK 227 E V S ++V ++++GK R A T MN SSRSH++F +++I++ +E E L GK Sbjct: 202 EIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEGEDMLKIGK 261 Query: 228 LYLVDLAGSEKV 239 L LVDLAGSE V Sbjct: 262 LNLVDLAGSENV 273 >3WPN-A nrPDB Length = 382 Score = 141 bits (355), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 103/258 (39%), Positives = 141/258 (54%), Gaps = 29/258 (11%) Query: 8 SIKVMCRFRPLNEAEILRGDKFIPK---FKGEETVVIG------QGKPYVFDRVLPPNTT 58 +I+V+ R RP N AE I + + E +V G K Y FD V +T Sbjct: 24 NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTK 83 Query: 59 QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKL---------HDPQLMGII 109 Q VY + I+ +V+ GYN TIFAYGQT +GKT TMEG+ DP L GII Sbjct: 84 QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDP-LAGII 142 Query: 110 PRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLL----DVSKTNLAVHEDKN-RVP 164 PR H IF+ + D EF +KVS EIY +++ DLL DVS+ + +N R Sbjct: 143 PRTLHQIFEKL--TDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGV 200 Query: 165 YVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINI--KQENVETEK 222 +KG E V + +EV ++++G A R A T MN +SSRSHS+F + I K+ ++ E+ Sbjct: 201 IIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEE 260 Query: 223 KLS-GKLYLVDLAGSEKV 239 + GKL LVDLAGSE + Sbjct: 261 LVKIGKLNLVDLAGSENI 278 >3H4S-A nrPDB Length = 386 Score = 140 bits (354), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 84/238 (35%), Positives = 131/238 (55%), Gaps = 11/238 (4%) Query: 9 IKVMCRFRPLNEAEILRGDK----FIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYN 64 I+V CR RPLNE E +K + +F E + K +++DRV +Q+ ++ Sbjct: 15 IRVYCRIRPLNEKESSEREKQMLTTVDEFTVEHPWKDDKRKQHIYDRVFDMRASQDDIFE 74 Query: 65 ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMD 124 K +V+ ++GYN IFAYGQT SGKT T+ G +P G+ PR ++F+ + Sbjct: 75 DT-KYLVQSAVDGYNVCIFAYGQTGSGKTFTIYGHESNP---GLTPRATKELFNILKRDS 130 Query: 125 ENLEFHIKVSYFEIYLDKIRDLL---DVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 181 + F +K E+Y D + DLL + L + +D + +V+ T +S+ EE+ Sbjct: 131 KRFSFSLKAYMVELYQDTLVDLLLPKSARRLKLEIKKDSKGMVFVENVTTIPISTLEELR 190 Query: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 +++ G RHV+ TNMNE SSRSH I + I+ +++T+ GKL VDLAGSE+V Sbjct: 191 MILERGSERRHVSGTNMNEESSRSHLILSVVIESIDLQTQSAARGKLSFVDLAGSERV 248 >4BN2-A nrPDB Length = 361 Score = 140 bits (352), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 88/210 (41%), Positives = 118/210 (56%), Gaps = 22/210 (10%) Query: 45 KPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP- 103 K + FD V +TTQE V+ AK IV+ + GYNGTIFAYGQT SGKT TM G Sbjct: 54 KTFTFDHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDN 113 Query: 104 ---QLMGIIPRIAHDIFDHIYSM-DENLE-------FHIKVSYFEIYLDKIRDLLDVSKT 152 L G+IPR F++++S+ D E F K S+ EIY ++I DLLD + Sbjct: 114 FSHNLRGVIPR----SFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASA 169 Query: 153 NLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLIN 212 L + E + +V G E+ V+S E V+ G NR VA T+MN SSRSH++F I Sbjct: 170 GLYLREHIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTIT 229 Query: 213 IKQENVETEKKL----SGKLYLVDLAGSEK 238 I E++E ++ + L LVDLAGSE+ Sbjct: 230 I--ESMEKSNEIVNIRTSLLNLVDLAGSER 257 >3CNZ-A nrPDB Length = 369 Score = 139 bits (349), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 89/239 (37%), Positives = 128/239 (53%), Gaps = 13/239 (5%) Query: 9 IKVMCRFRPLNEAEILRGDK----FIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYN 64 I+V CR RPL E EI+ ++ + +F E + K +++DRV N TQ+ V+ Sbjct: 7 IRVYCRLRPLCEKEIIAKERNAIRSVDEFTVEHLWKDDKAKQHMYDRVFDGNATQDDVFE 66 Query: 65 ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMD 124 K +V+ ++GYN IFAYGQT SGKT T+ G +P G+ PR ++F I D Sbjct: 67 DT-KYLVQSAVDGYNVCIFAYGQTGSGKTFTIYGADSNP---GLTPRAMSELF-RIMKKD 121 Query: 125 EN-LEFHIKVSYFEIYLDKIRDLL---DVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180 N F +K E+Y D + DLL + L + +D + V+ T +S+ EE+ Sbjct: 122 SNKFSFSLKAYMVELYQDTLVDLLLPKQAKRLKLDIKKDSKGMVSVENVTVVSISTYEEL 181 Query: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 +I G RH T MNE SSRSH I + I+ N++T+ GKL VDLAGSE+V Sbjct: 182 KTIIQRGSEQRHTTGTLMNEQSSRSHLIVSVIIESTNLQTQAIARGKLSFVDLAGSERV 240 >2OWM-A nrPDB Length = 443 Score = 137 bits (345), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 86/225 (38%), Positives = 126/225 (56%), Gaps = 22/225 (9%) Query: 34 KGEETVVIGQGKPYVFDRVLPPN-------TTQEQVYNACAKQIVKDVLEGYNGTIFAYG 86 +G + + + K + FD+ + TQE VY++ ++ + EGY+ IFAYG Sbjct: 85 RGARSRRVLEEKSFTFDKSFWSHNTEDEHYATQEHVYDSLGEEFLDHNFEGYHTCIFAYG 144 Query: 87 QTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDE---NLEFHIKVSYFEIYLDKI 143 QT SGK++TM G P G+IPR D+F I S + N+ +++KVSYFE+Y + + Sbjct: 145 QTGSGKSYTMMGTPDQP---GLIPRTCEDLFQRIASAQDETPNISYNVKVSYFEVYNEHV 201 Query: 144 RDLLDVSKTN-----LAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNM 198 RDLL N L V E PYVK TE V EE++ + G +R VA T M Sbjct: 202 RDLLAPVVPNKPPYYLKVRESPTEGPYVKDLTEVPVRGLEEIIRWMRIGDGSRTVASTKM 261 Query: 199 NEHSSRSHSIFLINIKQ--ENVETE--KKLSGKLYLVDLAGSEKV 239 N+ SSRSH++F I +KQ ++ET+ + S ++ LVDLAGSE+ Sbjct: 262 NDTSSRSHAVFTIMLKQIHHDLETDDTTERSSRIRLVDLAGSERA 306 >5WDE-A nrPDB Length = 330 Score = 134 bits (338), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 84/241 (34%), Positives = 133/241 (55%), Gaps = 13/241 (5%) Query: 8 SIKVMCRFRPLN--EAEILRGDKFIPKFKGEETVV--IGQGKPYVF--DRVLPPNTTQEQ 61 +I+V+ R RP+ + E + +++++ + +GKP F D+V P +Q+ Sbjct: 5 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 64 Query: 62 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY 121 V+ + +V ++G+N IFAYGQT +GKT+TMEG +P GI R +F + Sbjct: 65 VFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFSEVQ 120 Query: 122 SMDENLEFHIKVSYFEIYLDKIRDLLD---VSKTNLAVHEDKNRVPYVKGCTERFVSSPE 178 + E+ I VS EIY + +RDLL K + + D + YV G TE V S + Sbjct: 121 EKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVD 180 Query: 179 EVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEK 238 ++ V + G NR TN+NEHSSRSH++ ++ ++ + T + +GKL LVDLAGSE+ Sbjct: 181 DINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSER 240 Query: 239 V 239 V Sbjct: 241 V 241 >4OZQ-A nrPDB Length = 720 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 88/254 (34%), Positives = 126/254 (49%), Gaps = 27/254 (10%) Query: 9 IKVMCRFRPLNEAEILRGDKFIPKFKGEETVV-----------IGQGKPYVFDRVLPPNT 57 + V R RP ++ E + GEE V I + FD P Sbjct: 376 VTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFIYDVSFWSFDECHPGYA 435 Query: 58 TQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIF 117 +Q VY A ++ EGYN +FAYGQT SGK++TM G +P GIIPR D+F Sbjct: 436 SQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGKSYTMMGLNEEP---GIIPRFCEDLF 492 Query: 118 DHIYSMDEN-LEFHIKVSYFEIYLDKIRDLLDVSKTN------LAVHEDKNRVPYVKGCT 170 I + + +H+++S+FE+Y +KI DLL N L E PYV+G + Sbjct: 493 AQIAKKQTSEVSYHLEMSFFEVYNEKIHDLLVCKGENGQRKQPLRAREHPVSGPYVEGLS 552 Query: 171 ERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIF---LINIKQENVETEK---KL 224 VSS ++ ++ G R A T MN+ SSRSHS+F + K E VE E+ ++ Sbjct: 553 MNVVSSYSDIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHRI 612 Query: 225 SGKLYLVDLAGSEK 238 + ++ LVDLAGSE+ Sbjct: 613 TSRINLVDLAGSER 626 >5OAM-K nrPDB Length = 377 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 98/262 (37%), Positives = 135/262 (51%), Gaps = 39/262 (14%) Query: 9 IKVMCRFRPLNEAEILRG--------DK----FIPK------FKGEET----VVIGQGK- 45 +KV+ R RP N E G DK F PK F G++T V+ Q K Sbjct: 15 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 74 Query: 46 -PYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ 104 +VFD V +TQ +V+ K I++ L GYN T+ AYG T +GKTHTM G +P Sbjct: 75 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPG 134 Query: 105 LMGIIPRIAHDIFDHIYS-MDENLEFHI---KVSYFEIYLDKIRDLLDVSKTNLAVHEDK 160 +M + H+Y MDE E I VSY E+Y ++IRDLL V+ LAV ED Sbjct: 135 VMYL-------TMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL-VNSGPLAVREDT 186 Query: 161 NRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVET 220 + V G T S EE++ ++D G NR T+MN SSRSH++F I ++Q++ Sbjct: 187 QKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTA 246 Query: 221 EKKLS---GKLYLVDLAGSEKV 239 + K+ L+DLAGSE+ Sbjct: 247 SINQNVRIAKMSLIDLAGSERA 268 >5M5O-C nrPDB Length = 369 Score = 125 bits (314), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 90/271 (33%), Positives = 134/271 (49%), Gaps = 37/271 (13%) Query: 3 DPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIG-QGKP--------YVFDRVL 53 D E +I V+ R R + E+ G + Q P Y FD+V Sbjct: 4 DENETNINVVVRVRGRTDQEVRDNSSLAVSTSGAMGAELAIQSDPSSMLVTKTYAFDKVF 63 Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD-----PQLMGI 108 P Q ++ +++ VL GYN TIFAYGQT +GKT+TM G L D + G+ Sbjct: 64 GPEADQLMLFENSVAPMLEQVLNGYNCTIFAYGQTGTGKTYTMSGDLSDSDGILSEGAGL 123 Query: 109 IPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLAVHEDKNRVPY 165 IPR + +F + + N E+ +K SY+E+Y ++IRDLL VS + V ED +R Sbjct: 124 IPRALYQLFSSLD--NSNQEYAVKCSYYELYNEEIRDLL-VSEELRKPARVFEDTSRRGN 180 Query: 166 V--KGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE------- 216 V G E ++ + + + ++ EG R VA T N+ SSRSHSIF I + ++ Sbjct: 181 VVITGIEESYIKNAGDGLRLLREGSHRRQVAATKCNDLSSRSHSIFTITLHRKVSSGMTD 240 Query: 217 -------NVETEKKL-SGKLYLVDLAGSEKV 239 N ++ L + KL++VDLAGSE + Sbjct: 241 ETNSLTINNNSDDLLRASKLHMVDLAGSENI 271 >6NJE-A nrPDB Length = 379 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 70/197 (35%), Positives = 108/197 (54%), Gaps = 11/197 (5%) Query: 47 YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106 Y FD +TQ+ +Y + I++ +LEG N ++ AYG T +GKTHTM G P+ Sbjct: 67 YQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLG---SPEQP 123 Query: 107 GIIPRIAHDIFDHIYSMDENLE-----FHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKN 161 G+IPR D+ + +E E + +SY EIY +K+ DLLD + +L + ED Sbjct: 124 GVIPRALMDLLQ--LTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCR 181 Query: 162 RVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ-ENVET 220 + G +++ +SS + NR V T +N+ SSRSH++ L+ + Q E + Sbjct: 182 GNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAP 241 Query: 221 EKKLSGKLYLVDLAGSE 237 ++ GKLYL+DLAGSE Sbjct: 242 FRQREGKLYLIDLAGSE 258 >5MLV-G nrPDB Length = 432 Score = 124 bits (312), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 90/271 (33%), Positives = 134/271 (49%), Gaps = 37/271 (13%) Query: 3 DPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIG-QGKP--------YVFDRVL 53 D E +I V+ R R + E+ G + Q P Y FD+V Sbjct: 67 DENETNINVVVRVRGRTDQEVRDNSSLAVSTSGAMGAELAIQSDPSSMLVTKTYAFDKVF 126 Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD-----PQLMGI 108 P Q ++ +++ VL GYN TIFAYGQT +GKT+TM G L D + G+ Sbjct: 127 GPEADQLMLFENSVAPMLEQVLNGYNCTIFAYGQTGTGKTYTMSGDLSDSDGILSEGAGL 186 Query: 109 IPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLAVHEDKNRVPY 165 IPR + +F + + N E+ +K SY+E+Y ++IRDLL VS + V ED +R Sbjct: 187 IPRALYQLFSSLD--NSNQEYAVKCSYYELYNEEIRDLL-VSEELRKPARVFEDTSRRGN 243 Query: 166 V--KGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE------- 216 V G E ++ + + + ++ EG R VA T N+ SSRSHSIF I + ++ Sbjct: 244 VVITGIEESYIKNAGDGLRLLREGSHRRQVAATKCNDLSSRSHSIFTITLHRKVSSGMTD 303 Query: 217 -------NVETEKKL-SGKLYLVDLAGSEKV 239 N ++ L + KL++VDLAGSE + Sbjct: 304 ETNSLTINNNSDDLLRASKLHMVDLAGSENI 334 >5WDH-A nrPDB Length = 376 Score = 123 bits (308), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 92/263 (34%), Positives = 124/263 (47%), Gaps = 33/263 (12%) Query: 9 IKVMCRFRPL--NEAEILRGDKFIPKFKGEET----------------VVIGQGKP---- 46 I+V CR RP+ E G P G + + G P Sbjct: 24 IRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPPRH 83 Query: 47 -YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLH-DPQ 104 + FDRV PP + Q++V+ A +V+ L+GY IFAYGQT SGKT TMEG DPQ Sbjct: 84 DFSFDRVFPPGSGQDEVFEEIA-MLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQ 142 Query: 105 LMGIIPRIAHDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLAVHEDKN 161 L G+IPR +F + + + SY EIY + +RDLL K E + Sbjct: 143 LEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRR 202 Query: 162 RVPYVKGCT---ERFV--SSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE 216 P + T R+V S +EV ++ + NR VA T NE SSRSHS+F + I E Sbjct: 203 AGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGE 262 Query: 217 NVETEKKLSGKLYLVDLAGSEKV 239 + + L LVDLAGSE++ Sbjct: 263 HSSRGLQCGAPLSLVDLAGSERL 285 >2GRY-A nrPDB Length = 420 Score = 122 bits (307), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 93/255 (36%), Positives = 129/255 (50%), Gaps = 25/255 (9%) Query: 2 ADPA-ECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYV------------ 48 ADP E I V R RPLN+ E D + ++ V++ + K V Sbjct: 83 ADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFR 142 Query: 49 FDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTM----EGKLHDPQ 104 FD + E VY A+ +V+ + E T FAYGQT SGKTHTM GK D Sbjct: 143 FDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCS 202 Query: 105 LMGIIPRIAHDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRV 163 GI A D+F + + + LE + ++FEIY K+ DLL+ KT L V ED + Sbjct: 203 -KGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLN-RKTKLRVLEDGKQQ 260 Query: 164 PYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK 223 V G ER V E+V+ +ID G + R T+ N HSSRSH++F I ++++ K Sbjct: 261 VQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQIILRRKG-----K 315 Query: 224 LSGKLYLVDLAGSEK 238 L GK L+DLAG+E+ Sbjct: 316 LHGKFSLIDLAGNER 330 >3T0Q-A nrPDB Length = 349 Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 86/257 (33%), Positives = 135/257 (52%), Gaps = 33/257 (12%) Query: 8 SIKVMCRFRP--LNEAEILRGDKFIPKF---KGEETVVIGQGKPYV------FDRVLPPN 56 +I+V CR RP LNE + + I KF KG +++ I + + + FD + P+ Sbjct: 6 NIRVYCRVRPPLLNEPQDM-SHILIEKFNEAKGAQSLTINRNEGRILSYNFQFDMIFEPS 64 Query: 57 TTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDI 116 T ++++ +Q+V+ L+GYN IFAYGQT SGKT+TM G+IP I Sbjct: 65 HTNKEIFEEI-RQLVQSSLDGYNVCIFAYGQTGSGKTYTMLNAGD-----GMIPMTLSHI 118 Query: 117 FDHIYSMDE-NLEFHIKVSYFEIY----LDKIRD---------LLDVSKTNLAVHEDKNR 162 F ++ E + ++ Y EIY LD +RD +LD K ++ H+ + + Sbjct: 119 FKWTANLKERGWNYEMECEYIEIYNETILDLLRDFKSHDNIDEILDSQKHDIR-HDHEKQ 177 Query: 163 VPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEK 222 Y+ T ++S +V ++ + R A T NE SSRSHS+F+++I N+ T + Sbjct: 178 GTYITNVTRMKMTSTSQVDTILKKASKMRSTAATRSNERSSRSHSVFMVHINGRNLHTGE 237 Query: 223 KLSGKLYLVDLAGSEKV 239 GKL LVDLAGSE++ Sbjct: 238 TSQGKLNLVDLAGSERI 254 >5MM7-K nrPDB Length = 457 Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 79/222 (35%), Positives = 115/222 (51%), Gaps = 29/222 (13%) Query: 45 KPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD-- 102 K Y FD+V P Q VY I+++V+ GYN TIFAYGQT +GKTHTMEG L Sbjct: 140 KSYHFDQVFGPEADQGMVYQDVVGPILEEVMSGYNCTIFAYGQTGTGKTHTMEGDLTSQM 199 Query: 103 ---PQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN------ 153 GIIPR + +F H + + ++ +K ++ E+Y +++RDLL + + Sbjct: 200 GTYSSEAGIIPRSLYRLF-HTLELSKE-DYSVKATFIELYNEELRDLLSIDSSTSSAEPS 257 Query: 154 ------------LAVHED-KNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNE 200 L +++D + + ++G E + + V+ G R +A TN NE Sbjct: 258 SSATATKEPQHALRMYDDARGKGVVIQGLEEVALKDAAHGLSVLRRGSQKRQIAATNCNE 317 Query: 201 HSSRSHSIFLIN--IKQENVETEKKLS-GKLYLVDLAGSEKV 239 SSRSHS+F + IK + E L GKL LVDLAGSE + Sbjct: 318 QSSRSHSVFTMTVFIKDKGSRGEDVLKIGKLNLVDLAGSENI 359 >5MM4-K nrPDB Length = 385 Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 79/222 (35%), Positives = 115/222 (51%), Gaps = 29/222 (13%) Query: 45 KPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD-- 102 K Y FD+V P Q VY I+++V+ GYN TIFAYGQT +GKTHTMEG L Sbjct: 68 KSYHFDQVFGPEADQGMVYQDVVGPILEEVMSGYNCTIFAYGQTGTGKTHTMEGDLTSQM 127 Query: 103 ---PQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN------ 153 GIIPR + +F H + + ++ +K ++ E+Y +++RDLL + + Sbjct: 128 GTYSSEAGIIPRSLYRLF-HTLELSKE-DYSVKATFIELYNEELRDLLSIDSSTSSAEPS 185 Query: 154 ------------LAVHED-KNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNE 200 L +++D + + ++G E + + V+ G R +A TN NE Sbjct: 186 SSATATKEPQHALRMYDDARGKGVVIQGLEEVALKDAAHGLSVLRRGSQKRQIAATNCNE 245 Query: 201 HSSRSHSIFLIN--IKQENVETEKKLS-GKLYLVDLAGSEKV 239 SSRSHS+F + IK + E L GKL LVDLAGSE + Sbjct: 246 QSSRSHSVFTMTVFIKDKGSRGEDVLKIGKLNLVDLAGSENI 287 >5W3D-A nrPDB Length = 412 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 84/243 (34%), Positives = 127/243 (52%), Gaps = 18/243 (7%) Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGEETV----VIGQGKP------YVFDRVLPPNT 57 +I+V CR RP E+E R + E TV + Q K + FD+V P + Sbjct: 60 NIRVFCRIRPPLESEENRM-CCTWTYHDESTVELQSIDAQAKSKMGQQIFSFDQVFHPLS 118 Query: 58 TQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIF 117 +Q ++ + +++ L+GYN IFAYGQT SGKT+TM+G P+ +G+IPR +F Sbjct: 119 SQSDIFEMVSP-LIQSALDGYNICIFAYGQTGSGKTYTMDGV---PESVGVIPRTVDLLF 174 Query: 118 DHIYSM-DENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVP--YVKGCTERFV 174 D I + E+ IK ++ EIY + + DLL + ++ + KN YV TE V Sbjct: 175 DSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIYVSNITEETV 234 Query: 175 SSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLA 234 P + ++ K NR A T NE SSRSH++ + + + E ++ G + LVDLA Sbjct: 235 LDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIGRHAEKQEISVGSINLVDLA 294 Query: 235 GSE 237 GSE Sbjct: 295 GSE 297 >3NWN-A nrPDB Length = 359 Score = 121 bits (304), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 72/192 (37%), Positives = 109/192 (56%), Gaps = 10/192 (5%) Query: 56 NTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHD 115 + +Q+ VY AK +V L+GYNGTI YGQT +GKT+TM G + + GI+PR Sbjct: 82 DASQDLVYETVAKDVVSQALDGYNGTIMCYGQTGAGKTYTMMGATENYKHRGILPRALQQ 141 Query: 116 IFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDV------SKTNLAVHEDKNRVPYVKGC 169 +F I + ++VSY EIY + + DLL S T + + E+ V ++KG Sbjct: 142 VFRMIEERPTH-AITVRVSYLEIYNESLFDLLSTLPYVGPSVTPMTIVENPQGV-FIKGL 199 Query: 170 TERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIK--QENVETEKKLSGK 227 + S E+ ++ EG+ NR +A MN++SSRSH IF I ++ + EK ++ K Sbjct: 200 SVHLTSQEEDAFSLLFEGETNRIIASHTMNKNSSRSHCIFTIYLEAHSRTLSEEKYITSK 259 Query: 228 LYLVDLAGSEKV 239 + LVDLAGSE++ Sbjct: 260 INLVDLAGSERL 271 >3EDL-D nrPDB Length = 331 Score = 119 bits (297), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 86/247 (34%), Positives = 123/247 (49%), Gaps = 24/247 (9%) Query: 9 IKVMCRFRPLNEAEILRGDKFI-------------PKFKGEETVVIGQGKPYVFDRVLPP 55 I V R RPLN+ E+ + + + PK K + T + + + + FD Sbjct: 1 ICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYL-ENQAFCFDFAFDE 59 Query: 56 NTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL---MGIIPRI 112 + E VY A+ +V+ + EG T FAYGQT SGKTHTM G L GI Sbjct: 60 TASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKSQNASKGIYAMA 119 Query: 113 AHDIF-DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTE 171 + D+F NL + V++FEIY K+ DLL+ K L V ED + V G E Sbjct: 120 SRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLN-KKAKLRVLEDSRQQVQVVGLQE 178 Query: 172 RFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLV 231 V+ ++V+ +I+ G A R T N +SSRSH+ F I ++ T+ +L GK LV Sbjct: 179 YLVTCADDVIKMINMGSACRTSGQTFANSNSSRSHACFQILLR-----TKGRLHGKFSLV 233 Query: 232 DLAGSEK 238 DLAG+E+ Sbjct: 234 DLAGNER 240 >5XJA-A nrPDB Length = 426 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 90/259 (34%), Positives = 128/259 (49%), Gaps = 31/259 (11%) Query: 1 MADP-AECSIKVMCRFRPLNEAEILRGDKFI-------------PKFKGEETVVIGQGKP 46 + DP E I V R RPLN+ E+ + + + PK K + T + + + Sbjct: 80 VTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYL-ENQA 138 Query: 47 YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL- 105 + FD + E VY A+ +V+ + EG T FAYGQT SGKTHTM G L Sbjct: 139 FCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKSQN 198 Query: 106 --MGIIPRIAHDIF----DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHED 159 GI + D+F Y NL + V++FEIY K+ DLL+ K L V ED Sbjct: 199 ASKGIYAMASRDVFLLKNQPRY---RNLNLEVYVTFFEIYNGKVFDLLN-KKAKLRVLED 254 Query: 160 KNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVE 219 + V G E V+ ++V+ +I+ G A R T N +SSRSH+ F I ++ Sbjct: 255 SRQQVQVVGLQEYLVTCADDVIKMINMGSACRTSGQTFANSNSSRSHACFQILLR----- 309 Query: 220 TEKKLSGKLYLVDLAGSEK 238 T+ +L GK LVDLAG+E+ Sbjct: 310 TKGRLHGKFSLVDLAGNER 328 >3J2U-K nrPDB Length = 374 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 85/252 (33%), Positives = 123/252 (48%), Gaps = 22/252 (8%) Query: 4 PAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYV------------FDR 51 P+ SI V R RP++ E+ R + + ++ +++ + + V FD Sbjct: 33 PSSRSITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLTKFLENHKFRFDY 92 Query: 52 VLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTM----EGKLHDPQLMG 107 VY AK +VK + EG T FAYGQT SGKTHTM GK+ D + G Sbjct: 93 AFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCK-NG 151 Query: 108 IIPRIAHDIFDHI-YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYV 166 I A D+F + + + S+FEIY K+ DLL K L V ED + V Sbjct: 152 IYAMAAKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLS-DKQKLRVLEDGKQQVQV 210 Query: 167 KGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSG 226 G TE+ V EEV+ +I G A R T+ N +SSRSH++F I ++ + K+ G Sbjct: 211 VGLTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQG---STKIHG 267 Query: 227 KLYLVDLAGSEK 238 K +DLAG+E+ Sbjct: 268 KFSFIDLAGNER 279 >4UBF-A nrPDB Length = 387 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 90/259 (34%), Positives = 127/259 (49%), Gaps = 31/259 (11%) Query: 1 MADP-AECSIKVMCRFRPLNEAEILRGDKFI-------------PKFKGEETVVIGQGKP 46 M DP E I V R RPLN+ E+ + + + PK K + T + + + Sbjct: 44 MTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYL-ENQA 102 Query: 47 YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL- 105 + FD + E VY A+ +V+ + EG T FAYGQT SGKTHTM G L Sbjct: 103 FCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKAQN 162 Query: 106 --MGIIPRIAHDIF----DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHED 159 GI + D+F Y L + V++FEIY K+ DLL+ K L V ED Sbjct: 163 ASKGIYAMASRDVFLLKNQPCY---RKLGLEVYVTFFEIYNGKLFDLLN-KKAKLRVLED 218 Query: 160 KNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVE 219 + V G E V+S ++V+ +ID G A R T N +SSRSH+ F I ++ + Sbjct: 219 GKQQVQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSNSSRSHACFQIILRAKG-- 276 Query: 220 TEKKLSGKLYLVDLAGSEK 238 ++ GK LVDLAG+E+ Sbjct: 277 ---RMHGKFSLVDLAGNER 292 >5MIO-C nrPDB Length = 573 Score = 117 bits (292), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 90/259 (34%), Positives = 126/259 (48%), Gaps = 31/259 (11%) Query: 1 MADP-AECSIKVMCRFRPLNEAEILRGDKFI-------------PKFKGEETVVIGQGKP 46 M DP E I V R RPLN+ E+ + + + PK K + T + + + Sbjct: 37 MTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYL-ENQA 95 Query: 47 YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL- 105 + FD + E VY A +V+ + EG T FAYGQT SGKTHTM G L Sbjct: 96 FCFDFAFDETASNEVVYRFTAAPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKAQN 155 Query: 106 --MGIIPRIAHDIF----DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHED 159 GI + D+F Y L + V++FEIY K+ DLL+ K L V ED Sbjct: 156 ASKGIYAMASADVFLLKNQPCY---RKLGLEVYVTFFEIYNGKLFDLLN-KKAKLRVLED 211 Query: 160 KNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVE 219 + V G E V+S ++V+ +ID G A R T N +SSRSH+ F I ++ + Sbjct: 212 GKQQVQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSNSSRSHACFQIILRAKG-- 269 Query: 220 TEKKLSGKLYLVDLAGSEK 238 ++ GK LVDLAG+E+ Sbjct: 270 ---RMHGKFSLVDLAGNER 285 >6B0I-K nrPDB Length = 419 Score = 114 bits (285), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 83/247 (33%), Positives = 120/247 (48%), Gaps = 22/247 (8%) Query: 9 IKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYV------------FDRVLPPN 56 I V R RP++ E+ R + + ++ +++ + + V FD Sbjct: 83 ITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLTKFLENHKFRFDYAFNDT 142 Query: 57 TTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTM----EGKLHDPQLMGIIPRI 112 VY AK +VK + EG T FAYGQT SGKTHTM GK+ D + GI Sbjct: 143 CDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCK-NGIYAMA 201 Query: 113 AHDIFDHI-YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTE 171 A D+F + + + S+FEIY K+ DLL K L V ED + V G TE Sbjct: 202 AKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLS-DKQKLRVLEDGKQQVQVVGLTE 260 Query: 172 RFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLV 231 + V EEV+ +I G A R T+ N +SSRSH++F I ++ + K+ GK + Sbjct: 261 KVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQG---STKIHGKFSFI 317 Query: 232 DLAGSEK 238 DLAG+E+ Sbjct: 318 DLAGNER 324 >4GKR-A nrPDB Length = 371 Score = 112 bits (280), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 82/253 (32%), Positives = 128/253 (50%), Gaps = 27/253 (10%) Query: 8 SIKVMCRFRPL--NEAEILRGDKFIP--KFKGEETVVIGQGK----PYVFDRVLPPNTTQ 59 +I+V CR RP +E + + K P G++ + I +G P+ FD++ T Sbjct: 29 NIRVYCRIRPPLPHEDDNIEHIKVQPFDDDNGDQGMTINRGNSQVIPFKFDKIFDQQETN 88 Query: 60 EQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDH 119 ++++ Q+++ L+GYN IFAYGQT SGKT+TM +P GI+P + IF Sbjct: 89 DEIFKEVG-QLIQSSLDGYNVCIFAYGQTGSGKTYTM----LNPG-DGIVPATINHIFSW 142 Query: 120 IYSMD-ENLEFHIKVSYFEIYLDKIRDLL------------DVSKTNLAVHEDKNRVPYV 166 I + + + + EIY + I DLL + + H+ + + Y+ Sbjct: 143 IDKLAARGWSYKVSCEFIEIYNENIVDLLRSGAPSQENNDRNADSKHEIRHDQELKTTYI 202 Query: 167 KGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSG 226 T + S + V V+ R A T NEHSSRSHSIF+I+++ +N T +K G Sbjct: 203 TNITTCVLDSRDTVDKVLKRANKLRSTASTAANEHSSRSHSIFIIHLEGKNEGTGEKSQG 262 Query: 227 KLYLVDLAGSEKV 239 L LVDLAGSE++ Sbjct: 263 ILNLVDLAGSERL 275 >3DC4-A nrPDB Length = 344 Score = 107 bits (266), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 72/215 (33%), Positives = 117/215 (54%), Gaps = 20/215 (9%) Query: 31 PKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSS 90 P + +++++ Q + + FD P +Q+++Y A +V +LEG+ T AYGQT + Sbjct: 48 PPWSDGKSLIVDQNE-FHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGT 106 Query: 91 GKTHTM----EGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKV--SYFEIYLDKIR 144 GK+++M G++ P+ +GI+PR DIF+ + + EN + I+V S+ EIY +K Sbjct: 107 GKSYSMGMTPPGEI-LPEHLGILPRALGDIFERVTARQENNKDAIQVYASFIEIYNEKPF 165 Query: 145 DLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSR 204 DLL + V R CT + S ++ +++ G NR V TNMN +SSR Sbjct: 166 DLLGSTPHMPMVAARCQR------CTCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSR 219 Query: 205 SHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 SH+I I++K K ++ +VDLAGSE V Sbjct: 220 SHAIVTIHVK------SKTHHSRMNIVDLAGSEGV 248 >4H1G-A nrPDB Length = 715 Score = 103 bits (258), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 65/198 (32%), Positives = 107/198 (54%), Gaps = 11/198 (5%) Query: 47 YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106 ++FD++ + + V+ + Q+++ L+G N +FAYGQT SGKT TM + Sbjct: 432 FLFDKIFEREQSNDLVFEELS-QLIQCSLDGTNVCVFAYGQTGSGKTFTMSHPTN----- 485 Query: 107 GIIPRIAHDIFDHIYSMDE-NLEFHIKVSYFEIYLDKIRDLL----DVSKTNLAVHEDKN 161 G+IP IF+ I + E + ++ + EIY + I DLL D + H+D Sbjct: 486 GMIPLSLKKIFNDIEELKEKGWSYTVRGKFIEIYNEAIVDLLNPKIDPNTKYEIKHDDIA 545 Query: 162 RVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETE 221 V + + SPE+ + ++++ R A T N+HSSRSHSIF+I+++ N T+ Sbjct: 546 GKTTVTNVSTIDIKSPEQAITILNQANKKRSTAATKSNDHSSRSHSIFIIDLQGYNSLTK 605 Query: 222 KKLSGKLYLVDLAGSEKV 239 + G L L+DLAGSE++ Sbjct: 606 ESSYGTLNLIDLAGSERL 623 >1F9T-A nrPDB Length = 358 Score = 100 bits (249), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 85/258 (32%), Positives = 121/258 (46%), Gaps = 36/258 (13%) Query: 8 SIKVMCRFRP--------------LNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVL 53 +I+V CR RP +NE + G + + K + T Q + FD++ Sbjct: 15 NIRVYCRIRPALKNLENSDTSLINVNEFDDNSGVQSMEVTKIQNT---AQVHEFKFDKIF 71 Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113 T V+ Q+V+ L+GYN IFAYGQT SGKT TM +P GIIP Sbjct: 72 DQQDTNVDVFKEVG-QLVQSSLDGYNVCIFAYGQTGSGKTFTML----NPG-DGIIPSTI 125 Query: 114 HDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDLLDVSKTNLA---------VHEDKNRV 163 IF+ I + + ++ + + EIY + I DLL N + D+ Sbjct: 126 SHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRSDNNNKEDTSIGLKHEIRHDQETK 185 Query: 164 PYVKGCTERFVSSPEEVMDVIDEGKAN--RHVAVTNMNEHSSRSHSIFLINIKQENVETE 221 EE++++I + KAN R A T NEHSSRSHSIF+I++ N +T Sbjct: 186 TTTITNVTSCKLESEEMVEIILK-KANKLRSTASTASNEHSSRSHSIFIIHLSGSNAKTG 244 Query: 222 KKLSGKLYLVDLAGSEKV 239 G L LVDLAGSE++ Sbjct: 245 AHSYGTLNLVDLAGSERI 262 >1RY6-A nrPDB Length = 360 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 82/245 (33%), Positives = 118/245 (48%), Gaps = 19/245 (7%) Query: 9 IKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGK------------PYVFDRVLPPN 56 IKV+ R RPL+E E + D I K T+ I + + ++ D+V Sbjct: 2 IKVVVRKRPLSELEKKKKDSDIITVKNNCTLYIDEPRYKVDMTKYIERHEFIVDKVFDDT 61 Query: 57 TTQEQVYNACAKQIVKDVLE-GYNGTIFAYGQTSSGKTHTMEGKLHDPQ--LMGIIPRIA 113 VY K ++ D+ E G + FAYGQT SGKT+TM G Q GI A Sbjct: 62 VDNFTVYENTIKPLIIDLYENGCVCSCFAYGQTGSGKTYTMLGSQPYGQSDTPGIFQYAA 121 Query: 114 HDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERF 173 DIF + D++ I +S++EIY K+ DLL K A+ K V R Sbjct: 122 GDIFTFLNIYDKDNTKGIFISFYEIYCGKLYDLLQKRKMVAALENGKKEVVVKDLKILRV 181 Query: 174 VSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDL 233 ++ E ++ +ID G R + V + N+ SSRSH+I I++K N T GK+ +DL Sbjct: 182 LTKEELILKMID-GVLLRKIGVNSQNDESSRSHAILNIDLKDINKNTS---LGKIAFIDL 237 Query: 234 AGSEK 238 AGSE+ Sbjct: 238 AGSER 242 >4ETP-A nrPDB Length = 403 Score = 99.0 bits (245), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 74/210 (35%), Positives = 103/210 (49%), Gaps = 19/210 (9%) Query: 42 GQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLH 101 Q + FD++ T V+ Q+V+ L+GYN IFAYGQT SGKT TM Sbjct: 105 AQVHEFKFDKIFDQQDTNVDVFKEVG-QLVQSSLDGYNVAIFAYGQTGSGKTFTM----L 159 Query: 102 DPQLMGIIPRIAHDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDLLDVSKTNLA----- 155 +P GIIP IF+ I + + ++ + + EIY + I DLL N Sbjct: 160 NPG-DGIIPSTISHIFNWINKLKTKGWDYKVNAEFIEIYNENIVDLLRSDNNNKEDTSIG 218 Query: 156 ----VHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKAN--RHVAVTNMNEHSSRSHSIF 209 + D+ EE++++I + KAN R A T NEHSSRSHSIF Sbjct: 219 LKHEIRHDQETKTTTITNVTSVKLESEEMVEIILK-KANKLRSTASTASNEHSSRSHSIF 277 Query: 210 LINIKQENVETEKKLSGKLYLVDLAGSEKV 239 +I++ N +T G L LVDLAGSE++ Sbjct: 278 IIHLSGSNAKTGAHSYGTLNLVDLAGSERI 307 >5X3E-A nrPDB Length = 449 Score = 89.7 bits (221), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 83/312 (26%), Positives = 133/312 (42%), Gaps = 86/312 (27%) Query: 8 SIKVMCRFRP----------LNEAEILRGDKFIP--KFKGEETVVIGQGKPYVFDRVLPP 55 SI+V+CR P ++E I +P +F+ E + K + F RV Sbjct: 35 SIEVVCRLCPYTGSTPSLIAIDEGSI---QTVLPPAQFRRENAPQVE--KVFRFGRVFSE 89 Query: 56 NTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHD 115 N Q V+ + ++ ++L+G N +F YG T SGKT+TM GK + G++PR Sbjct: 90 NDGQATVFERTSVDLILNLLKGQNSLLFTYGVTGSGKTYTMTGKPTETG-TGLLPRTLDV 148 Query: 116 IFDHI----------------YSMDENLEFHIK--------------------------- 132 IF+ I + + L+ H+K Sbjct: 149 IFNSINNRVEKCIFYPSALNTFEIRATLDAHLKRHQMAADRLSTSREITDRYCEAIKLSG 208 Query: 133 ----------VSYFEIYLDKIRDLLDVSK----TNLAVHEDKNRVPYVKGCTERFVSSPE 178 V+Y EIY + DLL+ ++ T + D+ + YV G + VSS E Sbjct: 209 YNDDMVCSVFVTYVEIYNNYCYDLLEDARNGVLTKREIRHDRQQQMYVDGAKDVEVSSSE 268 Query: 179 EVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE-----------NVETEKKLSGK 227 E ++V G+ R V+ T +N+ SSRSHS+F I + +++ + + + Sbjct: 269 EALEVFCLGEERRRVSSTLLNKDSSRSHSVFTIKLVMAPRAYETKSVYPTMDSSQIIVSQ 328 Query: 228 LYLVDLAGSEKV 239 L LVDLAGSE+ Sbjct: 329 LCLVDLAGSERA 340 >5ND7-C nrPDB Length = 501 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 48/124 (38%), Positives = 70/124 (56%), Gaps = 8/124 (6%) Query: 122 SMDENLEFHIKVSYFEIYLDKIRDLLDV-----SKTNLAVHEDKNRVPYVKGCTERFVSS 176 S+ ++ F + +S+FEIY + + DLL+ + L + ED+N PYVK V Sbjct: 271 SVPADIRFSVWISFFEIYNELLYDLLEPPSHQHKRQTLRLCEDQNGNPYVKDLNWIHVRD 330 Query: 177 PEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETE--KKLSGKLYLVDLA 234 EE ++ G+ N+ A T+MN+ SSRSHSIF I I E + K+S +L L DLA Sbjct: 331 VEEAWKLLKVGRKNQSFASTHMNQQSSRSHSIFSIRILHLQGEGDIVPKIS-ELSLCDLA 389 Query: 235 GSEK 238 GSE+ Sbjct: 390 GSER 393 Score = 60.8 bits (146), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 21/130 (16%) Query: 9 IKVMCRFRPLNEAEILRG-DKFIPKFKGEETVV----------------IGQGK-PYVFD 50 +KV R RP +E+ R D+ + ET+V +GQ + F Sbjct: 44 VKVYLRIRPFLTSELDRQEDQGCVCIENTETLVLQAPKDSFALKSNERGVGQATHKFTFS 103 Query: 51 RVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIP 110 ++ P Q +N K++VKDVL+G N I+ YG T+SGKT+T++G D GI+P Sbjct: 104 QIFGPEVGQVAFFNLTMKEMVKDVLKGQNWLIYTYGVTNSGKTYTIQGTSKD---AGILP 160 Query: 111 RIAHDIFDHI 120 + IF+ + Sbjct: 161 QSLALIFNSL 170 >5ZFQ-A nrPDB Length = 390 Score = 35.8 bits (81), Expect = 0.016, Method: Compositional matrix adjust. Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 15/117 (12%) Query: 14 RFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNT-TQEQVYNACAKQIVK 72 +F NE ++ G K + +F+G V I +G RV+P T E++ +VK Sbjct: 88 KFEEANELDLSFGIKGLSRFRG--NVFIQRGAVAGVFRVIPYKILTFEELGLPV---VVK 142 Query: 73 DVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEF 129 ++ E G I G T SGK+ T L II +I + DHI ++++ +E+ Sbjct: 143 ELAEKPRGLILVTGPTGSGKSTT---------LAAIIDKINTERHDHIVTIEDPIEY 190 >5MUU-C nrPDB Length = 332 Score = 31.2 bits (69), Expect = 0.40, Method: Compositional matrix adjust. Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 8/77 (10%) Query: 78 YNGTIFAYGQTSSGKTHTMEGKLHDPQLM--GIIPRIAHDIFD---HIYSMDENLEFHIK 132 Y+G G T SGK+ T+ KL L+ G + A+D D HI ++DE L I Sbjct: 118 YSGVTALMGATGSGKSITLNEKLRPDVLIRWGEVAE-AYDELDTAVHISTLDEMLIVCIG 176 Query: 133 VSY--FEIYLDKIRDLL 147 + F + +D +R LL Sbjct: 177 LGALGFNVAVDSVRPLL 193 >4KT7-A nrPDB Length = 237 Score = 31.2 bits (69), Expect = 0.43, Method: Compositional matrix adjust. Identities = 18/37 (48%), Positives = 24/37 (64%), Gaps = 3/37 (8%) Query: 70 IVKDVLEGYNGTI-FAYGQTSSGKTHTMEG-KLHDPQ 104 I+KD+LE Y+G I + YG T+ + T EG K DPQ Sbjct: 67 IIKDILEKYDGNIRYVYGSTTR-ELSTFEGLKALDPQ 102 >3R8F-A nrPDB Length = 324 Score = 30.8 bits (68), Expect = 0.57, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 9/63 (14%) Query: 53 LPPNTTQEQVY----NACAKQIVKDVLEG----YNGTIFAYGQTSSGKTHTMEGKLHDPQ 104 L P T E N A ++VK+ LE YN IF YG +GKTH ++ ++ + Sbjct: 4 LNPKYTLENFIVGEGNRLAYEVVKEALENLGSLYN-PIFIYGSVGTGKTHLLQAAGNEAK 62 Query: 105 LMG 107 G Sbjct: 63 KRG 65 >2YW2-A nrPDB Length = 424 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 9/88 (10%) Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNG-TIFAYGQTSSGKTHTMEG--------KLHDPQ 104 P E+V ++IV+ V++G I+ G +G T EG +L DP+ Sbjct: 233 PTPVINEEVEKRIREEIVERVIKGLKEEGIYYRGFLYAGLMITKEGPKVLEFNVRLGDPE 292 Query: 105 LMGIIPRIAHDIFDHIYSMDENLEFHIK 132 I+ R+ +D + + + E + HIK Sbjct: 293 AQPILMRVKNDFLETLLNFYEGKDVHIK 320 >1FOB-A nrPDB Length = 334 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 2/53 (3%) Query: 91 GKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEF--HIKVSYFEIYLD 141 G+T +E L D + I R+ + D Y +D NLE +K + +YLD Sbjct: 27 GQTQALETILADAGINSIRQRVWVNPSDGSYDLDYNLELAKRVKAAGMSLYLD 79 >1DDZ-A nrPDB Length = 496 Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 19/73 (26%) Query: 49 FDRVLPPNTTQEQVYNACAKQIVKDVLEG-----YNGTIFAYGQTSSGKTHTMEGKLHDP 103 +R++ N EQ++N CA IV+D + G ++ G +GKL D Sbjct: 430 LNRLIEINVL-EQMHNVCATSIVQDAWDAGQELEVQGVVYGVG----------DGKLRD- 477 Query: 104 QLMGIIPRIAHDI 116 MG++ + DI Sbjct: 478 --MGVVAKANDDI 488 >5A5T-C nrPDB Length = 843 Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust. Identities = 13/43 (30%), Positives = 25/43 (58%) Query: 107 GIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDV 149 G+I +I +I +Y + NL ++K ++ LD I +L+D+ Sbjct: 299 GVIVKIKFNIIASLYDYNPNLATYMKPEMWQKCLDCINELMDI 341 >1G6H-A nrPDB Length = 257 Score = 27.7 bits (60), Expect = 4.2, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Query: 102 DPQLMGIIPRIAHDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDL 146 D + G+ P +AHDIF+H+ + + + F I +I L+ I L Sbjct: 178 DEPIAGVAPGLAHDIFNHVLELKAKGITFLIIEHRLDIVLNYIDHL 223 >3J8B-C nrPDB Length = 547 Score = 26.6 bits (57), Expect = 9.1, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 25/47 (53%) Query: 107 GIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN 153 G+I +I +I +Y + NL ++K + LD I +L+D+ N Sbjct: 44 GVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFAN 90 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3X2T-A nrPDB 388 e-109 2KIN-A nrPDB 386 e-108 5HNZ-K nrPDB 367 e-102 4UXT-C nrPDB 366 e-102 3J8Y-K nrPDB 361 e-100 2Y5W-A nrPDB 339 6e-94 1GOJ-A nrPDB 315 8e-87 3B6U-A nrPDB 299 1e-81 3B6V-A nrPDB 298 1e-81 4UXR-C nrPDB 295 1e-80 5MIO-C nrPDB 291 2e-79 4UBF-A nrPDB 290 3e-79 5XJA-A nrPDB 289 6e-79 3ZFC-A nrPDB 287 2e-78 6A1Z-A nrPDB 286 5e-78 2VVG-A nrPDB 285 7e-78 3EDL-D nrPDB 285 1e-77 1T5C-A nrPDB 284 2e-77 2GRY-A nrPDB 282 1e-76 3GBJ-A nrPDB 282 1e-76 4OZQ-A nrPDB 281 2e-76 2WBE-C nrPDB 277 2e-75 5GSZ-A nrPDB 275 1e-74 3J2U-K nrPDB 275 1e-74 6B0I-K nrPDB 274 3e-74 5WDE-A nrPDB 274 3e-74 3H4S-A nrPDB 273 6e-74 3WPN-A nrPDB 271 2e-73 4BN2-A nrPDB 269 7e-73 3CNZ-A nrPDB 268 2e-72 3T0Q-A nrPDB 266 5e-72 5W3D-A nrPDB 266 6e-72 4GKR-A nrPDB 264 2e-71 2XT3-A nrPDB 264 2e-71 5OAM-K nrPDB 259 1e-69 5MLV-G nrPDB 258 2e-69 5WDH-A nrPDB 257 2e-69 5M5O-C nrPDB 256 7e-69 2OWM-A nrPDB 256 7e-69 1F9T-A nrPDB 251 2e-67 6NJE-A nrPDB 247 2e-66 5MM7-K nrPDB 247 5e-66 4ETP-A nrPDB 245 9e-66 4H1G-A nrPDB 244 3e-65 5MM4-K nrPDB 243 6e-65 1RY6-A nrPDB 236 5e-63 3DC4-A nrPDB 235 2e-62 3NWN-A nrPDB 233 4e-62 5X3E-A nrPDB 206 7e-54 5ND7-C nrPDB 149 1e-36 Sequences not found previously or not previously below threshold: 5UJM-E nrPDB 32 0.29 5UJ7-E nrPDB 32 0.30 3R8F-A nrPDB 31 0.56 1C4O-A nrPDB 30 1.0 1D9Z-A nrPDB 30 1.1 4QTS-C nrPDB 29 1.5 2NMV-A nrPDB 29 1.5 4A2W-A nrPDB 28 3.0 4A2Q-A nrPDB 28 3.1 5O9J-A nrPDB 28 3.4 5N56-A nrPDB 28 3.7 4Q48-A nrPDB 28 3.8 4A36-A nrPDB 28 3.9 1A9V-A nrPDB 28 4.4 5MP4-A nrPDB 27 5.1 2QBY-A nrPDB 27 5.3 3WGO-A nrPDB 27 5.4 3L51-A nrPDB 27 5.9 1A7J-A nrPDB 27 9.3 3UGS-B nrPDB 27 9.8 CONVERGED! >3X2T-A nrPDB Length = 341 Score = 388 bits (998), Expect = e-109, Method: Composition-based stats. Identities = 239/239 (100%), Positives = 239/239 (100%) Query: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQE 60 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQE Sbjct: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQE 60 Query: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI Sbjct: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120 Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV Sbjct: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180 Query: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV Sbjct: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 >2KIN-A nrPDB Length = 238 Score = 386 bits (992), Expect = e-108, Method: Composition-based stats. Identities = 238/238 (100%), Positives = 238/238 (100%) Query: 2 ADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQ 61 ADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQ Sbjct: 1 ADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQ 60 Query: 62 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY 121 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY Sbjct: 61 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY 120 Query: 122 SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 181 SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVM Sbjct: 121 SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 180 Query: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV Sbjct: 181 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 238 >5HNZ-K nrPDB Length = 371 Score = 367 bits (944), Expect = e-102, Method: Composition-based stats. Identities = 228/233 (97%), Positives = 230/233 (98%), Gaps = 1/233 (0%) Query: 7 CSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNAC 66 +IKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI QGKPYVFDRVLPPNTTQEQVYNAC Sbjct: 23 GNIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI-QGKPYVFDRVLPPNTTQEQVYNAC 81 Query: 67 AKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDEN 126 AKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDEN Sbjct: 82 AKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDEN 141 Query: 127 LEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDE 186 LEF IKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDE Sbjct: 142 LEFAIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDE 201 Query: 187 GKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 GK+NRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV Sbjct: 202 GKSNRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 254 >4UXT-C nrPDB Length = 340 Score = 366 bits (939), Expect = e-102, Method: Composition-based stats. Identities = 212/235 (90%), Positives = 228/235 (97%), Gaps = 1/235 (0%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYN 64 ECSIKV+CRFRPLN+AEILRGDKFIP F+G+++VVIG GKPYVFDRV PPNTTQEQVY+ Sbjct: 6 NECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVYH 64 Query: 65 ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMD 124 ACA QIVKDVL GYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA DIF+HIYSMD Sbjct: 65 ACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMD 124 Query: 125 ENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVI 184 ENLEFHIKVSYFEIYLDKIRDLLDV+KTNL+VHEDKNRVP+VKGCTERFVSSPEE++DVI Sbjct: 125 ENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVI 184 Query: 185 DEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 DEGK+NRHVAVTNMNEHSSRSHSIFLINIKQEN+ETE+KLSGKLYLVDLAGSEKV Sbjct: 185 DEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKV 239 >3J8Y-K nrPDB Length = 349 Score = 361 bits (927), Expect = e-100, Method: Composition-based stats. Identities = 203/239 (84%), Positives = 221/239 (92%), Gaps = 1/239 (0%) Query: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQE 60 MAD AE +IKVMCRFRPLNE+E+ RGDK+I KF+GE+TVVI KPY FDRV +T+QE Sbjct: 1 MADLAESNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIA-SKPYAFDRVFQSSTSQE 59 Query: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120 QVYN CAK+IVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP+ MGIIPRI DIF++I Sbjct: 60 QVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYI 119 Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNL+VHEDKNRVPYVKG TERFVSSP+EV Sbjct: 120 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEV 179 Query: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 MD IDEGK+NRHVAVTNMNEHSSRSHSIFLIN+KQEN +TE+KLSGKLYLVDLAGSEKV Sbjct: 180 MDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKV 238 >2Y5W-A nrPDB Length = 365 Score = 339 bits (870), Expect = 6e-94, Method: Composition-based stats. Identities = 176/238 (73%), Positives = 202/238 (84%), Gaps = 2/238 (0%) Query: 4 PAECSIKVMCRFRPLNEAEILRGDKFIPKFKG--EETVVIGQGKPYVFDRVLPPNTTQEQ 61 PAE SIKV+CRFRPLN++E G KF+ KF EE + GK Y+FD+V PN +QE+ Sbjct: 8 PAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFDKVFKPNASQEK 67 Query: 62 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY 121 VYN AK IV DVL GYNGTIFAYGQTSSGKTHTMEG + D GIIPRI +DIF+HIY Sbjct: 68 VYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIY 127 Query: 122 SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 181 +M+ NLEFHIKVSY+EIY+DKIRDLLDVSK NL+VHEDKNRVPYVKG TERFVSSPE+V Sbjct: 128 AMEVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVF 187 Query: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 +VI+EGK+NRH+AVTNMNEHSSRSHS+FLIN+KQEN+E +KKLSGKLYLVDLAGSEKV Sbjct: 188 EVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKV 245 >1GOJ-A nrPDB Length = 355 Score = 315 bits (809), Expect = 8e-87, Method: Composition-based stats. Identities = 120/240 (50%), Positives = 155/240 (64%), Gaps = 4/240 (1%) Query: 4 PAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGK---PYVFDRVLPPNTTQE 60 + SIKV+ RFRP N EI G + I F+G +T + + + FDRV + Q Sbjct: 3 SSANSIKVVARFRPQNRVEIESGGQPIVTFQGPDTCTVDSKEAQGSFTFDRVFDMSCKQS 62 Query: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKL-HDPQLMGIIPRIAHDIFDH 119 +++ K V D+L GYNGT+FAYGQT +GK++TM G DP G+IPRI IF Sbjct: 63 DIFDFSIKPTVDDILNGYNGTVFAYGQTGAGKSYTMMGTSIDDPDGRGVIPRIVEQIFTS 122 Query: 120 IYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEE 179 I S N+E+ ++VSY EIY+++IRDLL NL VHE+KNR YVKG E +VSS +E Sbjct: 123 ILSSAANIEYTVRVSYMEIYMERIRDLLAPQNDNLPVHEEKNRGVYVKGLLEIYVSSVQE 182 Query: 180 VMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 V +V+ G R VA TNMN+ SSRSHSIF+I I Q+NVET SG+L+LVDLAGSEKV Sbjct: 183 VYEVMRRGGNARAVAATNMNQESSRSHSIFVITITQKNVETGSAKSGQLFLVDLAGSEKV 242 >3B6U-A nrPDB Length = 372 Score = 299 bits (765), Expect = 1e-81, Method: Composition-based stats. Identities = 99/247 (40%), Positives = 140/247 (56%), Gaps = 14/247 (5%) Query: 5 AECSIKVMCRFRPLNEAEILRG-DKFI--------PKFKGEETVVIGQGKPYVFDRVLPP 55 + S++V+ R RP+N E DK + K + K + FD V Sbjct: 19 SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDW 78 Query: 56 NTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHD 115 N Q ++Y+ + +V VL+G+NGTIFAYGQT +GKT+TMEG DP+ G+IP Sbjct: 79 NAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDH 138 Query: 116 IFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN-LAVHEDKNRVPYVKGCTERFV 174 IF HI S +N ++ ++ SY EIY ++IRDLL +T L + E + YVK + Sbjct: 139 IFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVT 197 Query: 175 SSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE--NVETEKKLS-GKLYLV 231 S +E+ V++ G NR V TNMNEHSSRSH+IF+I I+ ++ E + GKL LV Sbjct: 198 KSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLV 257 Query: 232 DLAGSEK 238 DLAGSE+ Sbjct: 258 DLAGSER 264 >3B6V-A nrPDB Length = 395 Score = 298 bits (764), Expect = 1e-81, Method: Composition-based stats. Identities = 89/247 (36%), Positives = 139/247 (56%), Gaps = 14/247 (5%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFK---GEETVVIGQ------GKPYVFDRVLPP 55 A ++KV+ R RPL+ E G + I G+ T+ + K + FD V Sbjct: 19 ASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDA 78 Query: 56 NTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHD 115 ++ Q +Y+ + ++ VL+G+NGT+FAYGQT +GKT+TM+G +P+L G+IP Sbjct: 79 SSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEH 138 Query: 116 IFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN-LAVHEDKNRVPYVKGCTERFV 174 IF HI S +N ++ ++ SY EIY ++IRDLL L + E+ Y+K + Sbjct: 139 IFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVT 197 Query: 175 SSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK---LSGKLYLV 231 + +E+ V++ G R V T+MNE SSRSH+IF+I ++ ++ + GKL LV Sbjct: 198 KNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLV 257 Query: 232 DLAGSEK 238 DLAGSE+ Sbjct: 258 DLAGSER 264 >4UXR-C nrPDB Length = 375 Score = 295 bits (755), Expect = 1e-80, Method: Composition-based stats. Identities = 96/255 (37%), Positives = 143/255 (56%), Gaps = 21/255 (8%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQ------GKPYVFDRVLPPN-- 56 A S+KV R RP N E+ R K I + G T ++ K + FD + Sbjct: 8 AGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTS 67 Query: 57 ------TTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIP 110 +Q+QVY +++++ EGYN IFAYGQT +GK++TM GK Q GIIP Sbjct: 68 PEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQ-GIIP 126 Query: 111 RIAHDIFDHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDVS-KTNLAVHEDKNRVPYVKG 168 ++ D+F I + ++N+ + ++VSY EIY +++RDLL+ K NL V E PYV+ Sbjct: 127 QLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVED 186 Query: 169 CTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS--- 225 ++ V+S ++ D++D G R VA TNMNE SSRSH++F I Q+ + E ++ Sbjct: 187 LSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEK 246 Query: 226 -GKLYLVDLAGSEKV 239 K+ LVDLAGSE+ Sbjct: 247 VSKISLVDLAGSERA 261 >5MIO-C nrPDB Length = 573 Score = 291 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 86/255 (33%), Positives = 123/255 (48%), Gaps = 23/255 (9%) Query: 1 MADP-AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGK------------PY 47 M DP E I V R RPLN+ E+ + + + + +++ + K + Sbjct: 37 MTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAF 96 Query: 48 VFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL-- 105 FD + E VY A +V+ + EG T FAYGQT SGKTHTM G L Sbjct: 97 CFDFAFDETASNEVVYRFTAAPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKAQNA 156 Query: 106 -MGIIPRIAHDIF-DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRV 163 GI + D+F L + V++FEIY K+ DLL+ K L V ED + Sbjct: 157 SKGIYAMASADVFLLKNQPCYRKLGLEVYVTFFEIYNGKLFDLLN-KKAKLRVLEDGKQQ 215 Query: 164 PYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK 223 V G E V+S ++V+ +ID G A R T N +SSRSH+ F I ++ + + Sbjct: 216 VQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSNSSRSHACFQIILRAKG-----R 270 Query: 224 LSGKLYLVDLAGSEK 238 + GK LVDLAG+E+ Sbjct: 271 MHGKFSLVDLAGNER 285 >4UBF-A nrPDB Length = 387 Score = 290 bits (744), Expect = 3e-79, Method: Composition-based stats. Identities = 86/255 (33%), Positives = 124/255 (48%), Gaps = 23/255 (9%) Query: 1 MADP-AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGK------------PY 47 M DP E I V R RPLN+ E+ + + + + +++ + K + Sbjct: 44 MTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAF 103 Query: 48 VFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL-- 105 FD + E VY A+ +V+ + EG T FAYGQT SGKTHTM G L Sbjct: 104 CFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKAQNA 163 Query: 106 -MGIIPRIAHDIF-DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRV 163 GI + D+F L + V++FEIY K+ DLL+ K L V ED + Sbjct: 164 SKGIYAMASRDVFLLKNQPCYRKLGLEVYVTFFEIYNGKLFDLLN-KKAKLRVLEDGKQQ 222 Query: 164 PYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK 223 V G E V+S ++V+ +ID G A R T N +SSRSH+ F I ++ + + Sbjct: 223 VQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSNSSRSHACFQIILRAKG-----R 277 Query: 224 LSGKLYLVDLAGSEK 238 + GK LVDLAG+E+ Sbjct: 278 MHGKFSLVDLAGNER 292 >5XJA-A nrPDB Length = 426 Score = 289 bits (741), Expect = 6e-79, Method: Composition-based stats. Identities = 86/255 (33%), Positives = 125/255 (49%), Gaps = 23/255 (9%) Query: 1 MADP-AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGK------------PY 47 + DP E I V R RPLN+ E+ + + + + +++ + K + Sbjct: 80 VTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAF 139 Query: 48 VFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL-- 105 FD + E VY A+ +V+ + EG T FAYGQT SGKTHTM G L Sbjct: 140 CFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKSQNA 199 Query: 106 -MGIIPRIAHDIF-DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRV 163 GI + D+F NL + V++FEIY K+ DLL+ K L V ED + Sbjct: 200 SKGIYAMASRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLN-KKAKLRVLEDSRQQ 258 Query: 164 PYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK 223 V G E V+ ++V+ +I+ G A R T N +SSRSH+ F I ++ T+ + Sbjct: 259 VQVVGLQEYLVTCADDVIKMINMGSACRTSGQTFANSNSSRSHACFQILLR-----TKGR 313 Query: 224 LSGKLYLVDLAGSEK 238 L GK LVDLAG+E+ Sbjct: 314 LHGKFSLVDLAGNER 328 >3ZFC-A nrPDB Length = 350 Score = 287 bits (736), Expect = 2e-78, Method: Composition-based stats. Identities = 94/240 (39%), Positives = 134/240 (55%), Gaps = 10/240 (4%) Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKF-KGEETVVIGQGKPYVFDRVLPPNTTQEQVYNAC 66 ++V R RPL EI G + F GE VV+G K + +D V P+T QE+V+N Sbjct: 9 PVRVALRCRPLVSKEIKEGCQTCLSFVPGEPQVVVGNDKSFTYDFVFDPSTEQEEVFNTA 68 Query: 67 AKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGK----LHDPQLMGIIPRIAHDIFDHIYS 122 ++K V +GYN T+ AYGQT SGKT++M G +G+IPR+ +F I Sbjct: 69 VAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEHDSAIGVIPRVIQLLFKEINK 128 Query: 123 MDENLEFHIKVSYFEIYLDKIRDLLDVSK---TNLAVHEDKNRVPYVKGCTERFVSSPEE 179 + EF +KVSY EIY ++I DLL S+ T + + ED + G TE+ V + Sbjct: 129 KS-DFEFTLKVSYLEIYNEEILDLLCSSREKATQINIREDPKEGIKIVGLTEKTVLVASD 187 Query: 180 VMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENV-ETEKKLSGKLYLVDLAGSEK 238 + +++G +R VA T MN SSRSH+IF I+I+Q + KL+LVDLAGSE+ Sbjct: 188 TVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGSER 247 >6A1Z-A nrPDB Length = 395 Score = 286 bits (733), Expect = 5e-78, Method: Composition-based stats. Identities = 90/262 (34%), Positives = 133/262 (50%), Gaps = 30/262 (11%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI------------GQGKPYVFDRV 52 + +KV R RP+N EI K + + + ++ GQ K + +D Sbjct: 2 GDSKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPINTNLSKGDARGQPKIFAYDHC 61 Query: 53 LPP--------NTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ 104 Q+ V+ + I+++ +GYN IFAYGQT SGK++TM G P Sbjct: 62 FWSMDESVREKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP- 120 Query: 105 LMGIIPRIAHDIFDHIYSM-DENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLAVHEDKN 161 G+IPR+ +F+ +E F ++VSY EIY +K+RDLLD + L V E Sbjct: 121 --GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSV 178 Query: 162 RVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE----N 217 PYV G ++ V+S +++ ++ EG +R VA TNMNE SSRSH++F I + Sbjct: 179 LGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVK 238 Query: 218 VETEKKLSGKLYLVDLAGSEKV 239 T + GKL LVDLAGSE+ Sbjct: 239 SGTSGEKVGKLSLVDLAGSERA 260 >2VVG-A nrPDB Length = 350 Score = 285 bits (731), Expect = 7e-78, Method: Composition-based stats. Identities = 98/250 (39%), Positives = 133/250 (53%), Gaps = 20/250 (8%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFI--------------PKFKGEETVVIGQGKPYVFD 50 + +IKV+ R RPLN E I P+ + T + + FD Sbjct: 2 SSDNIKVIVRCRPLNARETRENALNIIRMDEASAQVIVDPPEQEKSATQAKKVPRTFTFD 61 Query: 51 RVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIP 110 V + ++ A K ++ VLEG+N TIFAYGQT +GKT TM G +P G IP Sbjct: 62 AVYDQTSCNYGIFQASFKPLIDAVLEGFNSTIFAYGQTGAGKTWTMGGNKEEP---GAIP 118 Query: 111 RIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCT 170 +FD I S N F + SY E+Y ++IRDL+ + T L + EDK R YV G + Sbjct: 119 NSFKHLFDAINSSSSNQNFLVIGSYLELYNEEIRDLI-KNNTKLPLKEDKTRGIYVDGLS 177 Query: 171 ERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENV--ETEKKLSGKL 228 V++ E+ ++D+G ANRHVA T MN+ SSRSHSIF++ I+ V E GKL Sbjct: 178 MHRVTTAAELSALMDKGFANRHVAATQMNDTSSRSHSIFMVRIECSEVIENKEVIRVGKL 237 Query: 229 YLVDLAGSEK 238 LVDLAGSE+ Sbjct: 238 NLVDLAGSER 247 >3EDL-D nrPDB Length = 331 Score = 285 bits (730), Expect = 1e-77, Method: Composition-based stats. Identities = 83/246 (33%), Positives = 121/246 (49%), Gaps = 22/246 (8%) Query: 9 IKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGK------------PYVFDRVLPPN 56 I V R RPLN+ E+ + + + + +++ + K + FD Sbjct: 1 ICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDET 60 Query: 57 TTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL---MGIIPRIA 113 + E VY A+ +V+ + EG T FAYGQT SGKTHTM G L GI + Sbjct: 61 ASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKSQNASKGIYAMAS 120 Query: 114 HDIF-DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTER 172 D+F NL + V++FEIY K+ DLL+ K L V ED + V G E Sbjct: 121 RDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLN-KKAKLRVLEDSRQQVQVVGLQEY 179 Query: 173 FVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVD 232 V+ ++V+ +I+ G A R T N +SSRSH+ F I ++ T+ +L GK LVD Sbjct: 180 LVTCADDVIKMINMGSACRTSGQTFANSNSSRSHACFQILLR-----TKGRLHGKFSLVD 234 Query: 233 LAGSEK 238 LAG+E+ Sbjct: 235 LAGNER 240 >1T5C-A nrPDB Length = 349 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 99/245 (40%), Positives = 133/245 (54%), Gaps = 15/245 (6%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVV--IGQGKPYVFDRVLPPNTTQEQV 62 E ++ V R RPLN E G+ +K + V+ + K + FDRV N T + V Sbjct: 2 EEGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNV 61 Query: 63 YNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYS 122 Y A I+ ++GYNGTIFAYGQT+SGKT+TM G +G+IPR HDIF I Sbjct: 62 YEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSED---HLGVIPRAIHDIFQKIKK 118 Query: 123 MDENLEFHIKVSYFEIYLDKIRDLLDVSK--TNLAVHEDKNRVPYVKGCTERFVSSPEEV 180 + EF ++VSY EIY + I DLL ++ L + ED NR YV TE V + E Sbjct: 119 FPDR-EFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMA 177 Query: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE------NVETEKKLSGKLYLVDLA 234 + I +G+ +RH T MN+ SSRSH+IF + ++ N E K L LVDLA Sbjct: 178 LKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVK-VSHLNLVDLA 236 Query: 235 GSEKV 239 GSE+ Sbjct: 237 GSERA 241 >2GRY-A nrPDB Length = 420 Score = 282 bits (721), Expect = 1e-76, Method: Composition-based stats. Identities = 90/254 (35%), Positives = 127/254 (50%), Gaps = 23/254 (9%) Query: 2 ADP-AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKP------------YV 48 ADP E I V R RPLN+ E D + ++ V++ + K + Sbjct: 83 ADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFR 142 Query: 49 FDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL--- 105 FD + E VY A+ +V+ + E T FAYGQT SGKTHTM G Sbjct: 143 FDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCS 202 Query: 106 MGIIPRIAHDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVP 164 GI A D+F + + + LE + ++FEIY K+ DLL+ KT L V ED + Sbjct: 203 KGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLN-RKTKLRVLEDGKQQV 261 Query: 165 YVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKL 224 V G ER V E+V+ +ID G + R T+ N HSSRSH++F I ++++ KL Sbjct: 262 QVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQIILRRKG-----KL 316 Query: 225 SGKLYLVDLAGSEK 238 GK L+DLAG+E+ Sbjct: 317 HGKFSLIDLAGNER 330 >3GBJ-A nrPDB Length = 354 Score = 282 bits (721), Expect = 1e-76, Method: Composition-based stats. Identities = 89/260 (34%), Positives = 130/260 (50%), Gaps = 30/260 (11%) Query: 7 CSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI------------GQGKPYVFDRVLP 54 +KV R RP+N E K + + ++ GQ K + +D Sbjct: 1 SKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCFW 60 Query: 55 P--------NTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106 Q+ V+ + I+++ +GYN IFAYGQT SGK++TM G P Sbjct: 61 SMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP--- 117 Query: 107 GIIPRIAHDIFDHIYSM-DENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLAVHEDKNRV 163 G+IPR+ +F+ +E F ++VSY EIY +K+RDLLD + L V E Sbjct: 118 GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG 177 Query: 164 PYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE----NVE 219 PYV G ++ V+S +++ ++ EG +R VA TNMNE SSRSH++F I + Sbjct: 178 PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG 237 Query: 220 TEKKLSGKLYLVDLAGSEKV 239 T + GKL LVDLAGSE+ Sbjct: 238 TSGEKVGKLSLVDLAGSERA 257 >4OZQ-A nrPDB Length = 720 Score = 281 bits (719), Expect = 2e-76, Method: Composition-based stats. Identities = 86/258 (33%), Positives = 124/258 (48%), Gaps = 27/258 (10%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVV-----------IGQGKPYVFDRVL 53 + V R RP ++ E + GEE V I + FD Sbjct: 372 ENSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFIYDVSFWSFDECH 431 Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113 P +Q VY A ++ EGYN +FAYGQT SGK++TM G +P GIIPR Sbjct: 432 PGYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGKSYTMMGLNEEP---GIIPRFC 488 Query: 114 HDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDLL------DVSKTNLAVHEDKNRVPYV 166 D+F I + +H+++S+FE+Y +KI DLL K L E PYV Sbjct: 489 EDLFAQIAKKQTSEVSYHLEMSFFEVYNEKIHDLLVCKGENGQRKQPLRAREHPVSGPYV 548 Query: 167 KGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ------ENVET 220 +G + VSS ++ ++ G R A T MN+ SSRSHS+F + + Q E E Sbjct: 549 EGLSMNVVSSYSDIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEH 608 Query: 221 EKKLSGKLYLVDLAGSEK 238 + +++ ++ LVDLAGSE+ Sbjct: 609 DHRITSRINLVDLAGSER 626 >2WBE-C nrPDB Length = 373 Score = 277 bits (710), Expect = 2e-75, Method: Composition-based stats. Identities = 93/255 (36%), Positives = 136/255 (53%), Gaps = 22/255 (8%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQG------KPYVFDRVLPPNTT 58 + +I+V R RPLN E + G VV K + FDR P + Sbjct: 21 SNQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDSKLTKKFTFDRSFGPESK 80 Query: 59 QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEG--------KLHDPQLMGIIP 110 Q VY+ ++++VL GYN T+FAYGQT +GKTHTM G D +GIIP Sbjct: 81 QCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIP 140 Query: 111 RIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLAVHED--KNRVPYVK 167 R +FD + M+ +E+ +++SY E+Y +++ DLL T + + +D K ++ Sbjct: 141 RALSHLFDELRMME--VEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDSTKKGSVIIQ 198 Query: 168 GCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLI--NIKQENVETEKKLS 225 G E V S ++V ++++GK R A T MN SSRSH++F I +I++ +E E L Sbjct: 199 GLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEGEDMLK 258 Query: 226 -GKLYLVDLAGSEKV 239 GKL LVDLAGSE V Sbjct: 259 IGKLNLVDLAGSENV 273 >5GSZ-A nrPDB Length = 353 Score = 275 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 86/256 (33%), Positives = 133/256 (51%), Gaps = 21/256 (8%) Query: 2 ADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVI---------------GQGKP 46 D + + V R RP++ AE+ G I E+ VV+ + K Sbjct: 5 GDSKDQQLMVALRVRPISVAELEEGATLIAHKMDEQMVVLMDPMEDPDDILRAHRSREKS 64 Query: 47 YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106 Y+FD TQE VY A K +++ V+ GYN T+FAYG T GKT+TM G H+P Sbjct: 65 YLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEP--- 121 Query: 107 GIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYV 166 GI R +D+F I ++E+ + +SY EIY + IRDLL+ + L + ED V V Sbjct: 122 GIYVRTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPALGYLELREDSKGVIQV 181 Query: 167 KGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVET---EKK 223 G TE + +E+M ++ +G R T N+ SSRSH++ + ++Q + ++ Sbjct: 182 AGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVKNILQEV 241 Query: 224 LSGKLYLVDLAGSEKV 239 G+L+++DLAGSE+ Sbjct: 242 RQGRLFMIDLAGSERA 257 >3J2U-K nrPDB Length = 374 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 82/251 (32%), Positives = 121/251 (48%), Gaps = 20/251 (7%) Query: 4 PAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKP------------YVFDR 51 P+ SI V R RP++ E+ R + + ++ +++ + + + FD Sbjct: 33 PSSRSITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLTKFLENHKFRFDY 92 Query: 52 VLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM---GI 108 VY AK +VK + EG T FAYGQT SGKTHTM G+ + GI Sbjct: 93 AFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCKNGI 152 Query: 109 IPRIAHDIFDHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVK 167 A D+F + + + S+FEIY K+ DLL K L V ED + V Sbjct: 153 YAMAAKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLS-DKQKLRVLEDGKQQVQVV 211 Query: 168 GCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGK 227 G TE+ V EEV+ +I G A R T+ N +SSRSH++F I ++ + K+ GK Sbjct: 212 GLTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRP---QGSTKIHGK 268 Query: 228 LYLVDLAGSEK 238 +DLAG+E+ Sbjct: 269 FSFIDLAGNER 279 >6B0I-K nrPDB Length = 419 Score = 274 bits (700), Expect = 3e-74, Method: Composition-based stats. Identities = 80/249 (32%), Positives = 119/249 (47%), Gaps = 20/249 (8%) Query: 6 ECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKP------------YVFDRVL 53 + I V R RP++ E+ R + + ++ +++ + + + FD Sbjct: 80 DHQITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLTKFLENHKFRFDYAF 139 Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM---GIIP 110 VY AK +VK + EG T FAYGQT SGKTHTM G+ + GI Sbjct: 140 NDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCKNGIYA 199 Query: 111 RIAHDIFDHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGC 169 A D+F + + + S+FEIY K+ DLL K L V ED + V G Sbjct: 200 MAAKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLS-DKQKLRVLEDGKQQVQVVGL 258 Query: 170 TERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLY 229 TE+ V EEV+ +I G A R T+ N +SSRSH++F I ++ + K+ GK Sbjct: 259 TEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRP---QGSTKIHGKFS 315 Query: 230 LVDLAGSEK 238 +DLAG+E+ Sbjct: 316 FIDLAGNER 324 >5WDE-A nrPDB Length = 330 Score = 274 bits (700), Expect = 3e-74, Method: Composition-based stats. Identities = 84/244 (34%), Positives = 135/244 (55%), Gaps = 13/244 (5%) Query: 5 AECSIKVMCRFRPLNE--AEILRGDKFIPKFKGEETVV--IGQGKPYVF--DRVLPPNTT 58 ++ +I+V+ R RP+ + E + +++++ + +GKP F D+V P + Sbjct: 2 SKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQAS 61 Query: 59 QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFD 118 Q+ V+ + +V ++G+N IFAYGQT +GKT+TMEG +P GI R +F Sbjct: 62 QQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFS 117 Query: 119 HIYSMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLAVHEDKNRVPYVKGCTERFVS 175 + + E+ I VS EIY + +RDLL K + + D + YV G TE V Sbjct: 118 EVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQ 177 Query: 176 SPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAG 235 S +++ V + G NR TN+NEHSSRSH++ ++ ++ + T + +GKL LVDLAG Sbjct: 178 SVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAG 237 Query: 236 SEKV 239 SE+V Sbjct: 238 SERV 241 >3H4S-A nrPDB Length = 386 Score = 273 bits (698), Expect = 6e-74, Method: Composition-based stats. Identities = 84/240 (35%), Positives = 131/240 (54%), Gaps = 11/240 (4%) Query: 7 CSIKVMCRFRPLNEAEILRGDKF----IPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQV 62 I+V CR RPLNE E +K + +F E + K +++DRV +Q+ + Sbjct: 13 GKIRVYCRIRPLNEKESSEREKQMLTTVDEFTVEHPWKDDKRKQHIYDRVFDMRASQDDI 72 Query: 63 YNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYS 122 + K +V+ ++GYN IFAYGQT SGKT T+ G +P G+ PR ++F+ + Sbjct: 73 FEDT-KYLVQSAVDGYNVCIFAYGQTGSGKTFTIYGHESNP---GLTPRATKELFNILKR 128 Query: 123 MDENLEFHIKVSYFEIYLDKIRDLL---DVSKTNLAVHEDKNRVPYVKGCTERFVSSPEE 179 + F +K E+Y D + DLL + L + +D + +V+ T +S+ EE Sbjct: 129 DSKRFSFSLKAYMVELYQDTLVDLLLPKSARRLKLEIKKDSKGMVFVENVTTIPISTLEE 188 Query: 180 VMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 + +++ G RHV+ TNMNE SSRSH I + I+ +++T+ GKL VDLAGSE+V Sbjct: 189 LRMILERGSERRHVSGTNMNEESSRSHLILSVVIESIDLQTQSAARGKLSFVDLAGSERV 248 >3WPN-A nrPDB Length = 382 Score = 271 bits (693), Expect = 2e-73, Method: Composition-based stats. Identities = 100/262 (38%), Positives = 140/262 (53%), Gaps = 27/262 (10%) Query: 3 DPAECSIKVMCRFRPLNEAEILRGDKFIPK---FKGEETVVIG------QGKPYVFDRVL 53 + +I+V+ R RP N AE I + + E +V G K Y FD V Sbjct: 19 EEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVF 78 Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEG--------KLHDPQL 105 +T Q VY + I+ +V+ GYN TIFAYGQT +GKT TMEG + L Sbjct: 79 GASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPL 138 Query: 106 MGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLAVHEDK-- 160 GIIPR H IF+ + D EF +KVS EIY +++ DLL+ S L + +D Sbjct: 139 AGIIPRTLHQIFEKL--TDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRN 196 Query: 161 NRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIF--LINIKQENV 218 R +KG E V + +EV ++++G A R A T MN +SSRSHS+F I++K+ + Sbjct: 197 KRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTI 256 Query: 219 ETEKKLS-GKLYLVDLAGSEKV 239 + E+ + GKL LVDLAGSE + Sbjct: 257 DGEELVKIGKLNLVDLAGSENI 278 >4BN2-A nrPDB Length = 361 Score = 269 bits (688), Expect = 7e-73, Method: Composition-based stats. Identities = 95/255 (37%), Positives = 123/255 (48%), Gaps = 17/255 (6%) Query: 1 MADP--AECSIKVMCRFRPLNEAEILRG--DKFIPKFKGEETVVIG---QGKPYVFDRVL 53 M P +IKV R RP E ++ + + K + FD V Sbjct: 3 MGQPSNEGDAIKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLHSNPEPKTFTFDHVA 62 Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ----LMGII 109 +TTQE V+ AK IV+ + GYNGTIFAYGQT SGKT TM G L G+I Sbjct: 63 DVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVI 122 Query: 110 PRIAHDIFDHIYSMDE----NLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPY 165 PR +F I E F K S+ EIY ++I DLLD + L + E + + Sbjct: 123 PRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASAGLYLREHIKKGVF 182 Query: 166 VKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETE--KK 223 V G E+ V+S E V+ G NR VA T+MN SSRSH++F I I+ E Sbjct: 183 VVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEKSNEIVNI 242 Query: 224 LSGKLYLVDLAGSEK 238 + L LVDLAGSE+ Sbjct: 243 RTSLLNLVDLAGSER 257 >3CNZ-A nrPDB Length = 369 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 86/240 (35%), Positives = 126/240 (52%), Gaps = 11/240 (4%) Query: 7 CSIKVMCRFRPLNEAEILRGDK----FIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQV 62 I+V CR RPL E EI+ ++ + +F E + K +++DRV N TQ+ V Sbjct: 5 GKIRVYCRLRPLCEKEIIAKERNAIRSVDEFTVEHLWKDDKAKQHMYDRVFDGNATQDDV 64 Query: 63 YNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYS 122 + K +V+ ++GYN IFAYGQT SGKT T+ G +P G+ PR ++F + Sbjct: 65 FEDT-KYLVQSAVDGYNVCIFAYGQTGSGKTFTIYGADSNP---GLTPRAMSELFRIMKK 120 Query: 123 MDENLEFHIKVSYFEIYLDKIRDLL---DVSKTNLAVHEDKNRVPYVKGCTERFVSSPEE 179 F +K E+Y D + DLL + L + +D + V+ T +S+ EE Sbjct: 121 DSNKFSFSLKAYMVELYQDTLVDLLLPKQAKRLKLDIKKDSKGMVSVENVTVVSISTYEE 180 Query: 180 VMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKV 239 + +I G RH T MNE SSRSH I + I+ N++T+ GKL VDLAGSE+V Sbjct: 181 LKTIIQRGSEQRHTTGTLMNEQSSRSHLIVSVIIESTNLQTQAIARGKLSFVDLAGSERV 240 >3T0Q-A nrPDB Length = 349 Score = 266 bits (681), Expect = 5e-72, Method: Composition-based stats. Identities = 80/257 (31%), Positives = 128/257 (49%), Gaps = 31/257 (12%) Query: 7 CSIKVMCRFRPLNEAEILRGDKFIPKF----KGEETVVIGQGKP------YVFDRVLPPN 56 +I+V CR RP E + + KG +++ I + + + FD + P+ Sbjct: 5 GNIRVYCRVRPPLLNEPQDMSHILIEKFNEAKGAQSLTINRNEGRILSYNFQFDMIFEPS 64 Query: 57 TTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDI 116 T ++++ +Q+V+ L+GYN IFAYGQT SGKT+TM G+IP I Sbjct: 65 HTNKEIFEE-IRQLVQSSLDGYNVCIFAYGQTGSGKTYTMLNAGD-----GMIPMTLSHI 118 Query: 117 FDHIYSMDE-NLEFHIKVSYFEIYLDKIRDLL-------------DVSKTNLAVHEDKNR 162 F ++ E + ++ Y EIY + I DLL D K ++ H+ + + Sbjct: 119 FKWTANLKERGWNYEMECEYIEIYNETILDLLRDFKSHDNIDEILDSQKHDIR-HDHEKQ 177 Query: 163 VPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEK 222 Y+ T ++S +V ++ + R A T NE SSRSHS+F+++I N+ T + Sbjct: 178 GTYITNVTRMKMTSTSQVDTILKKASKMRSTAATRSNERSSRSHSVFMVHINGRNLHTGE 237 Query: 223 KLSGKLYLVDLAGSEKV 239 GKL LVDLAGSE++ Sbjct: 238 TSQGKLNLVDLAGSERI 254 >5W3D-A nrPDB Length = 412 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 84/244 (34%), Positives = 127/244 (52%), Gaps = 18/244 (7%) Query: 7 CSIKVMCRFRPLNEAEILRGDKFIPKFKGEETV----VIGQGKP------YVFDRVLPPN 56 +I+V CR RP E+E R + E TV + Q K + FD+V P Sbjct: 59 GNIRVFCRIRPPLESEENRMC-CTWTYHDESTVELQSIDAQAKSKMGQQIFSFDQVFHPL 117 Query: 57 TTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDI 116 ++Q ++ + +++ L+GYN IFAYGQT SGKT+TM+G P+ +G+IPR + Sbjct: 118 SSQSDIFEMVS-PLIQSALDGYNICIFAYGQTGSGKTYTMDGV---PESVGVIPRTVDLL 173 Query: 117 FDHIYS-MDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRV--PYVKGCTERF 173 FD I + E+ IK ++ EIY + + DLL + ++ + KN YV TE Sbjct: 174 FDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIYVSNITEET 233 Query: 174 VSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDL 233 V P + ++ K NR A T NE SSRSH++ + + + E ++ G + LVDL Sbjct: 234 VLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIGRHAEKQEISVGSINLVDL 293 Query: 234 AGSE 237 AGSE Sbjct: 294 AGSE 297 >4GKR-A nrPDB Length = 371 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 79/254 (31%), Positives = 122/254 (48%), Gaps = 27/254 (10%) Query: 7 CSIKVMCRFRPLNEAEILR----GDKFIPKFKGEETVVIGQGK----PYVFDRVLPPNTT 58 +I+V CR RP E + G++ + I +G P+ FD++ T Sbjct: 28 GNIRVYCRIRPPLPHEDDNIEHIKVQPFDDDNGDQGMTINRGNSQVIPFKFDKIFDQQET 87 Query: 59 QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFD 118 ++++ Q+++ L+GYN IFAYGQT SGKT+TM GI+P + IF Sbjct: 88 NDEIFKEVG-QLIQSSLDGYNVCIFAYGQTGSGKTYTMLNPGD-----GIVPATINHIFS 141 Query: 119 HIYSMD-ENLEFHIKVSYFEIYLDKIRDLL------------DVSKTNLAVHEDKNRVPY 165 I + + + + EIY + I DLL + + H+ + + Y Sbjct: 142 WIDKLAARGWSYKVSCEFIEIYNENIVDLLRSGAPSQENNDRNADSKHEIRHDQELKTTY 201 Query: 166 VKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS 225 + T + S + V V+ R A T NEHSSRSHSIF+I+++ +N T +K Sbjct: 202 ITNITTCVLDSRDTVDKVLKRANKLRSTASTAANEHSSRSHSIFIIHLEGKNEGTGEKSQ 261 Query: 226 GKLYLVDLAGSEKV 239 G L LVDLAGSE++ Sbjct: 262 GILNLVDLAGSERL 275 >2XT3-A nrPDB Length = 344 Score = 264 bits (675), Expect = 2e-71, Method: Composition-based stats. Identities = 86/249 (34%), Positives = 131/249 (52%), Gaps = 15/249 (6%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKF-KGEETVVIGQGKPYVFDRVLPPNTTQEQVY 63 E ++V R RPL E+L G + + G V +G+ + + F VL + QE VY Sbjct: 9 EEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVY 68 Query: 64 NACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD---PQLMGIIPRIAHDIFDHI 120 AC + +++ EG+N T+FAYGQT SGKT+TM GI+PR + F I Sbjct: 69 QACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEAFKLI 128 Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNRVPYVKGCTERFVSSPE 178 D L+ + VSY E+Y ++ RDLL+V + ++ + ED+ + G E V + Sbjct: 129 DENDL-LDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGLD 187 Query: 179 EVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETE--------KKLSGKLYL 230 EV+ +++ G A RH T++N SSRSH++F + +KQ + L K + Sbjct: 188 EVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLKQRGRAPSRLPRPAPGQLLVSKFHF 247 Query: 231 VDLAGSEKV 239 VDLAGSE+V Sbjct: 248 VDLAGSERV 256 >5OAM-K nrPDB Length = 377 Score = 259 bits (662), Expect = 1e-69, Method: Composition-based stats. Identities = 87/260 (33%), Positives = 128/260 (49%), Gaps = 31/260 (11%) Query: 7 CSIKVMCRFRPLNEAEILRG------------------DKFIPKFKGEET----VVIGQG 44 +KV+ R RP N E G + + F G++T V+ Q Sbjct: 13 HHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQN 72 Query: 45 K--PYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD 102 K +VFD V +TQ +V+ K I++ L GYN T+ AYG T +GKTHTM G + Sbjct: 73 KDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADE 132 Query: 103 PQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNR 162 P +M + ++ + + E VSY E+Y ++IRDLL V+ LAV ED + Sbjct: 133 PGVMYL---TMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL-VNSGPLAVREDTQK 188 Query: 163 VPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETE- 221 V G T S EE++ ++D G NR T+MN SSRSH++F I ++Q++ Sbjct: 189 GVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASI 248 Query: 222 --KKLSGKLYLVDLAGSEKV 239 K+ L+DLAGSE+ Sbjct: 249 NQNVRIAKMSLIDLAGSERA 268 >5MLV-G nrPDB Length = 432 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 84/270 (31%), Positives = 128/270 (47%), Gaps = 35/270 (12%) Query: 3 DPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIG---------QGKPYVFDRVL 53 D E +I V+ R R + E+ G + K Y FD+V Sbjct: 67 DENETNINVVVRVRGRTDQEVRDNSSLAVSTSGAMGAELAIQSDPSSMLVTKTYAFDKVF 126 Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD-----PQLMGI 108 P Q ++ +++ VL GYN TIFAYGQT +GKT+TM G L D + G+ Sbjct: 127 GPEADQLMLFENSVAPMLEQVLNGYNCTIFAYGQTGTGKTYTMSGDLSDSDGILSEGAGL 186 Query: 109 IPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLAVHED--KNRVP 164 IPR + +F + + N E+ +K SY+E+Y ++IRDLL + V ED + Sbjct: 187 IPRALYQLFSSLD--NSNQEYAVKCSYYELYNEEIRDLLVSEELRKPARVFEDTSRRGNV 244 Query: 165 YVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE-------- 216 + G E ++ + + + ++ EG R VA T N+ SSRSHSIF I + ++ Sbjct: 245 VITGIEESYIKNAGDGLRLLREGSHRRQVAATKCNDLSSRSHSIFTITLHRKVSSGMTDE 304 Query: 217 -------NVETEKKLSGKLYLVDLAGSEKV 239 N + + KL++VDLAGSE + Sbjct: 305 TNSLTINNNSDDLLRASKLHMVDLAGSENI 334 >5WDH-A nrPDB Length = 376 Score = 257 bits (658), Expect = 2e-69, Method: Composition-based stats. Identities = 91/265 (34%), Positives = 123/265 (46%), Gaps = 33/265 (12%) Query: 7 CSIKVMCRFRPLNEAEI--LRGDKFIPKFKGEET----------------VVIGQGKP-- 46 +I+V CR RP+ E G P G + + G P Sbjct: 22 GNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPP 81 Query: 47 ---YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLH-D 102 + FDRV PP + Q++V+ A +V+ L+GY IFAYGQT SGKT TMEG D Sbjct: 82 RHDFSFDRVFPPGSGQDEVFEEIAM-LVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGD 140 Query: 103 PQLMGIIPRIAHDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDLL--DVSKTNLAVHED 159 PQL G+IPR +F + + + SY EIY + +RDLL K E Sbjct: 141 PQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEI 200 Query: 160 KNRVPYVKGCTE-----RFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIK 214 + P + T VS +EV ++ + NR VA T NE SSRSHS+F + I Sbjct: 201 RRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQIS 260 Query: 215 QENVETEKKLSGKLYLVDLAGSEKV 239 E+ + L LVDLAGSE++ Sbjct: 261 GEHSSRGLQCGAPLSLVDLAGSERL 285 >5M5O-C nrPDB Length = 369 Score = 256 bits (654), Expect = 7e-69, Method: Composition-based stats. Identities = 84/270 (31%), Positives = 128/270 (47%), Gaps = 35/270 (12%) Query: 3 DPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIG---------QGKPYVFDRVL 53 D E +I V+ R R + E+ G + K Y FD+V Sbjct: 4 DENETNINVVVRVRGRTDQEVRDNSSLAVSTSGAMGAELAIQSDPSSMLVTKTYAFDKVF 63 Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD-----PQLMGI 108 P Q ++ +++ VL GYN TIFAYGQT +GKT+TM G L D + G+ Sbjct: 64 GPEADQLMLFENSVAPMLEQVLNGYNCTIFAYGQTGTGKTYTMSGDLSDSDGILSEGAGL 123 Query: 109 IPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLAVHED--KNRVP 164 IPR + +F + + N E+ +K SY+E+Y ++IRDLL + V ED + Sbjct: 124 IPRALYQLFSSLD--NSNQEYAVKCSYYELYNEEIRDLLVSEELRKPARVFEDTSRRGNV 181 Query: 165 YVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE-------- 216 + G E ++ + + + ++ EG R VA T N+ SSRSHSIF I + ++ Sbjct: 182 VITGIEESYIKNAGDGLRLLREGSHRRQVAATKCNDLSSRSHSIFTITLHRKVSSGMTDE 241 Query: 217 -------NVETEKKLSGKLYLVDLAGSEKV 239 N + + KL++VDLAGSE + Sbjct: 242 TNSLTINNNSDDLLRASKLHMVDLAGSENI 271 >2OWM-A nrPDB Length = 443 Score = 256 bits (654), Expect = 7e-69, Method: Composition-based stats. Identities = 88/255 (34%), Positives = 133/255 (52%), Gaps = 24/255 (9%) Query: 6 ECSIKVMCRFRPLNEAE--ILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPN------- 56 E + + + P E ++ + +G + + + K + FD+ + Sbjct: 55 ERNAECIVEMDPATERTSLLVPQETDFADARGARSRRVLEEKSFTFDKSFWSHNTEDEHY 114 Query: 57 TTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDI 116 TQE VY++ ++ + EGY+ IFAYGQT SGK++TM G P G+IPR D+ Sbjct: 115 ATQEHVYDSLGEEFLDHNFEGYHTCIFAYGQTGSGKSYTMMGTPDQP---GLIPRTCEDL 171 Query: 117 FDHIYSMDE---NLEFHIKVSYFEIYLDKIRDLLDVSKTN-----LAVHEDKNRVPYVKG 168 F I S + N+ +++KVSYFE+Y + +RDLL N L V E PYVK Sbjct: 172 FQRIASAQDETPNISYNVKVSYFEVYNEHVRDLLAPVVPNKPPYYLKVRESPTEGPYVKD 231 Query: 169 CTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETE----KKL 224 TE V EE++ + G +R VA T MN+ SSRSH++F I +KQ + + E + Sbjct: 232 LTEVPVRGLEEIIRWMRIGDGSRTVASTKMNDTSSRSHAVFTIMLKQIHHDLETDDTTER 291 Query: 225 SGKLYLVDLAGSEKV 239 S ++ LVDLAGSE+ Sbjct: 292 SSRIRLVDLAGSERA 306 >1F9T-A nrPDB Length = 358 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 79/258 (30%), Positives = 117/258 (45%), Gaps = 34/258 (13%) Query: 7 CSIKVMCRFRP--------------LNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRV 52 +I+V CR RP +NE + G + + K + T + + + FD++ Sbjct: 14 GNIRVYCRIRPALKNLENSDTSLINVNEFDDNSGVQSMEVTKIQNTAQVHE---FKFDKI 70 Query: 53 LPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRI 112 T V+ Q+V+ L+GYN IFAYGQT SGKT TM GIIP Sbjct: 71 FDQQDTNVDVFKEVG-QLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGD-----GIIPST 124 Query: 113 AHDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDLLDVSKTNLA---------VHEDKNR 162 IF+ I + + ++ + + EIY + I DLL N + D+ Sbjct: 125 ISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRSDNNNKEDTSIGLKHEIRHDQET 184 Query: 163 VPYVKGCTERFVSSPEEVMDV-IDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETE 221 EE++++ + + R A T NEHSSRSHSIF+I++ N +T Sbjct: 185 KTTTITNVTSCKLESEEMVEIILKKANKLRSTASTASNEHSSRSHSIFIIHLSGSNAKTG 244 Query: 222 KKLSGKLYLVDLAGSEKV 239 G L LVDLAGSE++ Sbjct: 245 AHSYGTLNLVDLAGSERI 262 >6NJE-A nrPDB Length = 379 Score = 247 bits (632), Expect = 2e-66, Method: Composition-based stats. Identities = 73/241 (30%), Positives = 115/241 (47%), Gaps = 13/241 (5%) Query: 7 CSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGK------PYVFDRVLPPNTTQE 60 ++V R RP + D + ++ I + Y FD +TQ+ Sbjct: 21 ARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQ 80 Query: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120 +Y + I++ +LEG N ++ AYG T +GKTHTM G P G+IPR D+ Sbjct: 81 DIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQP---GVIPRALMDLLQLT 137 Query: 121 YSMDEN---LEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSP 177 + +SY EIY +K+ DLLD + +L + ED + G +++ +SS Sbjct: 138 REEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSF 197 Query: 178 EEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQEN-VETEKKLSGKLYLVDLAGS 236 + NR V T +N+ SSRSH++ L+ + Q + ++ GKLYL+DLAGS Sbjct: 198 ADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGS 257 Query: 237 E 237 E Sbjct: 258 E 258 >5MM7-K nrPDB Length = 457 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 90/291 (30%), Positives = 128/291 (43%), Gaps = 55/291 (18%) Query: 2 ADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIG------------------- 42 +D E +I+V+ R R E R I G I Sbjct: 71 SDAGESNIQVVVRVRGQAPNEPKRTAPGILTTSGPRCQQIDVAIEAPQVSSSSAIASTSN 130 Query: 43 -------QGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHT 95 + K Y FD+V P Q VY I+++V+ GYN TIFAYGQT +GKTHT Sbjct: 131 LVQESATRQKSYHFDQVFGPEADQGMVYQDVVGPILEEVMSGYNCTIFAYGQTGTGKTHT 190 Query: 96 MEGKLHD-----PQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVS 150 MEG L GIIPR + +F + E+ + +K ++ E+Y +++RDLL + Sbjct: 191 MEGDLTSQMGTYSSEAGIIPRSLYRLFHTLELSKED--YSVKATFIELYNEELRDLLSID 248 Query: 151 ------------------KTNLAVHEDKNR-VPYVKGCTERFVSSPEEVMDVIDEGKANR 191 + L +++D ++G E + + V+ G R Sbjct: 249 SSTSSAEPSSSATATKEPQHALRMYDDARGKGVVIQGLEEVALKDAAHGLSVLRRGSQKR 308 Query: 192 HVAVTNMNEHSSRSHSIFLIN--IKQENVETEKKLS-GKLYLVDLAGSEKV 239 +A TN NE SSRSHS+F + IK + E L GKL LVDLAGSE + Sbjct: 309 QIAATNCNEQSSRSHSVFTMTVFIKDKGSRGEDVLKIGKLNLVDLAGSENI 359 >4ETP-A nrPDB Length = 403 Score = 245 bits (627), Expect = 9e-66, Method: Composition-based stats. Identities = 78/258 (30%), Positives = 116/258 (44%), Gaps = 34/258 (13%) Query: 7 CSIKVMCRFRP--------------LNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRV 52 +I+V R RP +NE + G + + K + T + + + FD++ Sbjct: 59 GNIRVYLRIRPALKNLENSDTSLINVNEFDDNSGVQSMEVTKIQNTAQVHE---FKFDKI 115 Query: 53 LPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRI 112 T V+ Q+V+ L+GYN IFAYGQT SGKT TM GIIP Sbjct: 116 FDQQDTNVDVFKEVG-QLVQSSLDGYNVAIFAYGQTGSGKTFTMLNPGD-----GIIPST 169 Query: 113 AHDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDLLDVSKTNLA---------VHEDKNR 162 IF+ I + + ++ + + EIY + I DLL N + D+ Sbjct: 170 ISHIFNWINKLKTKGWDYKVNAEFIEIYNENIVDLLRSDNNNKEDTSIGLKHEIRHDQET 229 Query: 163 VPYVKGCTERFVSSPEEVMDV-IDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETE 221 EE++++ + + R A T NEHSSRSHSIF+I++ N +T Sbjct: 230 KTTTITNVTSVKLESEEMVEIILKKANKLRSTASTASNEHSSRSHSIFIIHLSGSNAKTG 289 Query: 222 KKLSGKLYLVDLAGSEKV 239 G L LVDLAGSE++ Sbjct: 290 AHSYGTLNLVDLAGSERI 307 >4H1G-A nrPDB Length = 715 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 71/256 (27%), Positives = 125/256 (48%), Gaps = 29/256 (11%) Query: 7 CSIKVMCRFRPLNEAEILRGD---KFIPKFKGEETVVIGQGKP---------------YV 48 +I+V CR R ++ + + I +++ + + + ++ Sbjct: 374 GNIRVFCRIRNVSSSSSSSSSSSSEDIIQYEAPQDINDESKQELVITRNINNNFSNLRFL 433 Query: 49 FDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGI 108 FD++ + + V+ + Q+++ L+G N +FAYGQT SGKT TM + G+ Sbjct: 434 FDKIFEREQSNDLVFEELS-QLIQCSLDGTNVCVFAYGQTGSGKTFTMSHPTN-----GM 487 Query: 109 IPRIAHDIFDHIYSMDE-NLEFHIKVSYFEIYLDKIRDLL----DVSKTNLAVHEDKNRV 163 IP IF+ I + E + ++ + EIY + I DLL D + H+D Sbjct: 488 IPLSLKKIFNDIEELKEKGWSYTVRGKFIEIYNEAIVDLLNPKIDPNTKYEIKHDDIAGK 547 Query: 164 PYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK 223 V + + SPE+ + ++++ R A T N+HSSRSHSIF+I+++ N T++ Sbjct: 548 TTVTNVSTIDIKSPEQAITILNQANKKRSTAATKSNDHSSRSHSIFIIDLQGYNSLTKES 607 Query: 224 LSGKLYLVDLAGSEKV 239 G L L+DLAGSE++ Sbjct: 608 SYGTLNLIDLAGSERL 623 >5MM4-K nrPDB Length = 385 Score = 243 bits (620), Expect = 6e-65, Method: Composition-based stats. Identities = 89/288 (30%), Positives = 126/288 (43%), Gaps = 55/288 (19%) Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIG---------------------- 42 E +I+V+ R R E R I G I Sbjct: 2 GESNIQVVVRVRGQAPNEPKRTAPGILTTSGPRCQQIDVAIEAPQVSSSSAIASTSNLVQ 61 Query: 43 ----QGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEG 98 + K Y FD+V P Q VY I+++V+ GYN TIFAYGQT +GKTHTMEG Sbjct: 62 ESATRQKSYHFDQVFGPEADQGMVYQDVVGPILEEVMSGYNCTIFAYGQTGTGKTHTMEG 121 Query: 99 KLHD-----PQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVS--- 150 L GIIPR + +F + E+ + +K ++ E+Y +++RDLL + Sbjct: 122 DLTSQMGTYSSEAGIIPRSLYRLFHTLELSKED--YSVKATFIELYNEELRDLLSIDSST 179 Query: 151 ---------------KTNLAVHEDKNR-VPYVKGCTERFVSSPEEVMDVIDEGKANRHVA 194 + L +++D ++G E + + V+ G R +A Sbjct: 180 SSAEPSSSATATKEPQHALRMYDDARGKGVVIQGLEEVALKDAAHGLSVLRRGSQKRQIA 239 Query: 195 VTNMNEHSSRSHSIFLIN--IKQENVETEKKLS-GKLYLVDLAGSEKV 239 TN NE SSRSHS+F + IK + E L GKL LVDLAGSE + Sbjct: 240 ATNCNEQSSRSHSVFTMTVFIKDKGSRGEDVLKIGKLNLVDLAGSENI 287 >1RY6-A nrPDB Length = 360 Score = 236 bits (603), Expect = 5e-63, Method: Composition-based stats. Identities = 82/245 (33%), Positives = 120/245 (48%), Gaps = 19/245 (7%) Query: 9 IKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGK------------PYVFDRVLPPN 56 IKV+ R RPL+E E + D I K T+ I + + ++ D+V Sbjct: 2 IKVVVRKRPLSELEKKKKDSDIITVKNNCTLYIDEPRYKVDMTKYIERHEFIVDKVFDDT 61 Query: 57 TTQEQVYNACAKQIVKDVLE-GYNGTIFAYGQTSSGKTHTMEGKLHDPQ--LMGIIPRIA 113 VY K ++ D+ E G + FAYGQT SGKT+TM G Q GI A Sbjct: 62 VDNFTVYENTIKPLIIDLYENGCVCSCFAYGQTGSGKTYTMLGSQPYGQSDTPGIFQYAA 121 Query: 114 HDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERF 173 DIF + D++ I +S++EIY K+ DLL K A+ E+ + VK Sbjct: 122 GDIFTFLNIYDKDNTKGIFISFYEIYCGKLYDLLQKRKMVAAL-ENGKKEVVVKDLKILR 180 Query: 174 VSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDL 233 V + EE++ + +G R + V + N+ SSRSH+I I++K N T GK+ +DL Sbjct: 181 VLTKEELILKMIDGVLLRKIGVNSQNDESSRSHAILNIDLKDINKNTSL---GKIAFIDL 237 Query: 234 AGSEK 238 AGSE+ Sbjct: 238 AGSER 242 >3DC4-A nrPDB Length = 344 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 73/242 (30%), Positives = 120/242 (49%), Gaps = 24/242 (9%) Query: 7 CSIKVMCRFRP----LNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQV 62 ++++ R P L E P + +++++ Q + + FD P +Q+++ Sbjct: 22 SAVRIAVREAPYRQFLGRRE--PSVVQFPPWSDGKSLIVDQNE-FHFDHAFPATISQDEM 78 Query: 63 YNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD---PQLMGIIPRIAHDIFDH 119 Y A +V +LEG+ T AYGQT +GK+++M P+ +GI+PR DIF+ Sbjct: 79 YQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEILPEHLGILPRALGDIFER 138 Query: 120 IYSMDENLE--FHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSP 177 + + EN + + S+ EIY +K DLL + V R CT + S Sbjct: 139 VTARQENNKDAIQVYASFIEIYNEKPFDLLGSTPHMPMVAARCQR------CTCLPLHSQ 192 Query: 178 EEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSE 237 ++ +++ G NR V TNMN +SSRSH+I I++K K ++ +VDLAGSE Sbjct: 193 ADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVK------SKTHHSRMNIVDLAGSE 246 Query: 238 KV 239 V Sbjct: 247 GV 248 >3NWN-A nrPDB Length = 359 Score = 233 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 82/246 (33%), Positives = 124/246 (50%), Gaps = 21/246 (8%) Query: 12 MCRFRPLNE--------AEILRGDKFIPKFKGEETVVIGQGKPYVF--DRVLPPNTTQEQ 61 R +P ++ + R K VV Q + F D VL +Q+ Sbjct: 29 FVRVKPTDDFAHEMIRYGDDKRSIDIHLKKDIRRGVVNNQQTDWSFKLDGVLHD-ASQDL 87 Query: 62 VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY 121 VY AK +V L+GYNGTI YGQT +GKT+TM G + + GI+PR +F I Sbjct: 88 VYETVAKDVVSQALDGYNGTIMCYGQTGAGKTYTMMGATENYKHRGILPRALQQVFRMIE 147 Query: 122 SMDENLEFHIKVSYFEIYLDKIRDLLD------VSKTNLAVHEDKNRVPYVKGCTERFVS 175 + ++VSY EIY + + DLL S T + + E+ + ++KG + S Sbjct: 148 ERPTH-AITVRVSYLEIYNESLFDLLSTLPYVGPSVTPMTIVENP-QGVFIKGLSVHLTS 205 Query: 176 SPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIK--QENVETEKKLSGKLYLVDL 233 E+ ++ EG+ NR +A MN++SSRSH IF I ++ + EK ++ K+ LVDL Sbjct: 206 QEEDAFSLLFEGETNRIIASHTMNKNSSRSHCIFTIYLEAHSRTLSEEKYITSKINLVDL 265 Query: 234 AGSEKV 239 AGSE++ Sbjct: 266 AGSERL 271 >5X3E-A nrPDB Length = 449 Score = 206 bits (524), Expect = 7e-54, Method: Composition-based stats. Identities = 79/313 (25%), Positives = 129/313 (41%), Gaps = 80/313 (25%) Query: 4 PAECSIKVMCRFRPLNEAE-----ILRGDKFIP----KFKGEETVVIGQGKPYVFDRVLP 54 SI+V+CR P + I G +F+ E + K + F RV Sbjct: 31 EETDSIEVVCRLCPYTGSTPSLIAIDEGSIQTVLPPAQFRRENAPQV--EKVFRFGRVFS 88 Query: 55 PNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAH 114 N Q V+ + ++ ++L+G N +F YG T SGKT+TM GK + G++PR Sbjct: 89 ENDGQATVFERTSVDLILNLLKGQNSLLFTYGVTGSGKTYTMTGKPTETGT-GLLPRTLD 147 Query: 115 DIFDHIYSM--------------------------------------------------- 123 IF+ I + Sbjct: 148 VIFNSINNRVEKCIFYPSALNTFEIRATLDAHLKRHQMAADRLSTSREITDRYCEAIKLS 207 Query: 124 --DENLEFHIKVSYFEIYLDKIRDLLDVSK----TNLAVHEDKNRVPYVKGCTERFVSSP 177 ++++ + V+Y EIY + DLL+ ++ T + D+ + YV G + VSS Sbjct: 208 GYNDDMVCSVFVTYVEIYNNYCYDLLEDARNGVLTKREIRHDRQQQMYVDGAKDVEVSSS 267 Query: 178 EEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE-----------NVETEKKLSG 226 EE ++V G+ R V+ T +N+ SSRSHS+F I + +++ + + Sbjct: 268 EEALEVFCLGEERRRVSSTLLNKDSSRSHSVFTIKLVMAPRAYETKSVYPTMDSSQIIVS 327 Query: 227 KLYLVDLAGSEKV 239 +L LVDLAGSE+ Sbjct: 328 QLCLVDLAGSERA 340 >5ND7-C nrPDB Length = 501 Score = 149 bits (376), Expect = 1e-36, Method: Composition-based stats. Identities = 46/123 (37%), Positives = 67/123 (54%), Gaps = 6/123 (4%) Query: 122 SMDENLEFHIKVSYFEIYLDKIRDLLDV-----SKTNLAVHEDKNRVPYVKGCTERFVSS 176 S+ ++ F + +S+FEIY + + DLL+ + L + ED+N PYVK V Sbjct: 271 SVPADIRFSVWISFFEIYNELLYDLLEPPSHQHKRQTLRLCEDQNGNPYVKDLNWIHVRD 330 Query: 177 PEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS-GKLYLVDLAG 235 EE ++ G+ N+ A T+MN+ SSRSHSIF I I E + +L L DLAG Sbjct: 331 VEEAWKLLKVGRKNQSFASTHMNQQSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAG 390 Query: 236 SEK 238 SE+ Sbjct: 391 SER 393 Score = 115 bits (288), Expect = 2e-26, Method: Composition-based stats. Identities = 47/191 (24%), Positives = 79/191 (41%), Gaps = 31/191 (16%) Query: 6 ECSIKVMCRFRPLNEAEILRG-DKFIPKFKGEETVVIGQGK-----------------PY 47 +KV R RP +E+ R D+ + ET+V+ K + Sbjct: 41 SEKVKVYLRIRPFLTSELDRQEDQGCVCIENTETLVLQAPKDSFALKSNERGVGQATHKF 100 Query: 48 VFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMG 107 F ++ P Q +N K++VKDVL+G N I+ YG T+SGKT+T++G D G Sbjct: 101 TFSQIFGPEVGQVAFFNLTMKEMVKDVLKGQNWLIYTYGVTNSGKTYTIQGTSKD---AG 157 Query: 108 IIPRIAHDIFDHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYV 166 I+P+ IF+ + + + +S + I + + E K + Sbjct: 158 ILPQSLALIFNSLQGQLHPTPDLKPLLS-----NEVIW----LDSKQIRQEEMKKLSLLI 208 Query: 167 KGCTERFVSSP 177 G E +S+ Sbjct: 209 GGLQEEELSTS 219 >5UJM-E nrPDB Length = 435 Score = 31.7 bits (71), Expect = 0.29, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 35/92 (38%), Gaps = 5/92 (5%) Query: 81 TIFAYGQTSSGKTHTMEGKLHDPQLMGIIPR-----IAHDIFDHIYSMDENLEFHIKVSY 135 +IF YG T+SGKT+ + L +L + + + I + +L Sbjct: 32 SIFIYGHTASGKTYVTQTLLKTLELPHVFVNCVECFTLRLLLEQILNKLNHLSSSEDGCS 91 Query: 136 FEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVK 167 EI + D + + K K++ Y+ Sbjct: 92 TEITCETFNDFVRLFKQVTTAENLKDQTVYIV 123 >5UJ7-E nrPDB Length = 284 Score = 31.7 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 38/103 (36%), Gaps = 5/103 (4%) Query: 81 TIFAYGQTSSGKTHTMEGKLHDPQLMGIIPR-----IAHDIFDHIYSMDENLEFHIKVSY 135 +IF YG T+SGKT+ + L +L + + + I + +L Sbjct: 32 SIFIYGHTASGKTYVTQTLLKTLELPHVFVNCVECFTLRLLLEQILNKLNHLSSSEDGCS 91 Query: 136 FEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPE 178 EI + D + + K K++ Y+ ++ E Sbjct: 92 TEITCETFNDFVRLFKQVTTAENLKDQTVYIVLDKAEYLRDME 134 >3R8F-A nrPDB Length = 324 Score = 30.6 bits (68), Expect = 0.56, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Query: 65 ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMG 107 K+ ++++ YN IF YG +GKTH ++ ++ + G Sbjct: 24 EVVKEALENLGSLYNP-IFIYGSVGTGKTHLLQAAGNEAKKRG 65 >1C4O-A nrPDB Length = 664 Score = 29.8 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 42/106 (39%), Gaps = 17/106 (16%) Query: 86 GQTSSGKTHTMEGKLHDPQLMG-------IIPRIAHDIFDHIYSMDENLEFHIKVSYFEI 138 G T +GKT TM + I+ F ++ + +E+ +SY++ Sbjct: 35 GATGTGKTVTMAKVIEALGRPALVLAPNKILAAQLAAEFRELFP-ENAVEY--FISYYDY 91 Query: 139 YLDKIRDLLDVSKTNLAVHEDKNRVPYVKGC---TERFVSSPEEVM 181 Y + V +L + +D + P ++ T R + + +V+ Sbjct: 92 YQPEAY----VPGKDLYIEKDASINPEIERLRHSTTRSLLTRRDVI 133 >1D9Z-A nrPDB Length = 657 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 24/63 (38%), Gaps = 4/63 (6%) Query: 86 GQTSSGKTHTMEGKLHDPQLMGII----PRIAHDIFDHIYSMDENLEFHIKVSYFEIYLD 141 G T +GKT T+ + ++ +A ++ + + VSY++ Y Sbjct: 39 GATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQP 98 Query: 142 KIR 144 + Sbjct: 99 EAY 101 >4QTS-C nrPDB Length = 268 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 30/87 (34%), Gaps = 24/87 (27%) Query: 7 CSIKVMCRFRPLNEAEILRGDKFIPKFKGEETV----------------VIGQGKPYVFD 50 ++V+ R + E + D + K E T+ + G + F+ Sbjct: 122 EPVRVIVR-DAYLQPEENKKDYDYLEIKVENTIDRLKGTTIKGGIRNMERVVAGSKFKFE 180 Query: 51 RVLPPNTTQEQVYNACAKQIVKDVLEG 77 V +Y K+++K +EG Sbjct: 181 VVFN-------IYKESDKELIKKFIEG 200 >2NMV-A nrPDB Length = 661 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 24/63 (38%), Gaps = 4/63 (6%) Query: 86 GQTSSGKTHTMEGKLHDPQLMGII----PRIAHDIFDHIYSMDENLEFHIKVSYFEIYLD 141 G T +GKT T+ + + ++ +A ++ N VSY++ Y Sbjct: 39 GATGTGKTFTVSNLIKEVNKPTLVIAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQP 98 Query: 142 KIR 144 + Sbjct: 99 EAY 101 >4A2W-A nrPDB Length = 936 Score = 28.2 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 13/26 (50%), Gaps = 2/26 (7%) Query: 69 QIVKDVLEGYNGTIFAYGQTSSGKTH 94 ++ + + G N I A T SGKT Sbjct: 255 ELAQPAINGKNALICA--PTGSGKTF 278 >4A2Q-A nrPDB Length = 797 Score = 28.2 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 13/26 (50%), Gaps = 2/26 (7%) Query: 69 QIVKDVLEGYNGTIFAYGQTSSGKTH 94 ++ + + G N I A T SGKT Sbjct: 255 ELAQPAINGKNALICA--PTGSGKTF 278 >5O9J-A nrPDB Length = 184 Score = 28.2 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 19/44 (43%), Gaps = 9/44 (20%) Query: 169 CTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLIN 212 +E E+ +++ EG V VT RSHS+F I Sbjct: 68 VSEVSRHPVSEMFEIVVEGNKK--VRVT-------RSHSVFTIR 102 >5N56-A nrPDB Length = 199 Score = 27.9 bits (61), Expect = 3.7, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 39/98 (39%), Gaps = 20/98 (20%) Query: 144 RDLLDV--SKTNLAVHEDKNRVPYVKGC------TERFVSSPEEVMDVIDEGKAN----- 190 D L+ K + +H D++ YV T+ S EE++ +D AN Sbjct: 12 FDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANLDSVPANIQTAV 71 Query: 191 RHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKL 228 R+ ++N HS+F + N E + + K+ Sbjct: 72 RNNGGGHLN------HSLFW-ELLSPNSEEKGTVVEKI 102 >4Q48-A nrPDB Length = 525 Score = 27.9 bits (61), Expect = 3.8, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 14/31 (45%), Gaps = 2/31 (6%) Query: 63 YNACAKQIVKDVLEGYNGTIFAYGQTSSGKT 93 + +IV+ V EG N + T GK+ Sbjct: 25 FRGVQGEIVQQVAEGGNALVLM--PTGGGKS 53 >4A36-A nrPDB Length = 556 Score = 27.9 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 13/26 (50%), Gaps = 2/26 (7%) Query: 69 QIVKDVLEGYNGTIFAYGQTSSGKTH 94 ++ + + G N I A T SGKT Sbjct: 14 ELAQPAINGKNALICA--PTGSGKTF 37 >1A9V-A nrPDB Length = 129 Score = 27.9 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 22/49 (44%), Gaps = 5/49 (10%) Query: 29 FIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEG 77 +P G E +I +GKP+ + V N + AK +K ++G Sbjct: 17 LVPGCHGSEPCIIHRGKPFQLEAVFEANQNTK-----TAKIEIKASIDG 60 >5MP4-A nrPDB Length = 198 Score = 27.5 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 21/56 (37%), Gaps = 2/56 (3%) Query: 72 KDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGII--PRIAHDIFDHIYSMDE 125 K L G F T G T+ L GII P ++F + +MDE Sbjct: 100 KGALHGKVAGCFVSTGTGGGNEATIMNSLSTLAHHGIIFVPLGYKNVFAELTNMDE 155 >2QBY-A nrPDB Length = 386 Score = 27.5 bits (60), Expect = 5.3, Method: Composition-based stats. Identities = 8/12 (66%), Positives = 9/12 (75%) Query: 82 IFAYGQTSSGKT 93 IF YG T +GKT Sbjct: 48 IFIYGLTGTGKT 59 >3WGO-A nrPDB Length = 326 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 14/35 (40%), Gaps = 2/35 (5%) Query: 111 RIAHDIFDH--IYSMDENLEFHIKVSYFEIYLDKI 143 IF I +D N + +S E+Y D + Sbjct: 29 MELEAIFTRRDINKVDSNNSKLVHISRLELYKDTV 63 >3L51-A nrPDB Length = 161 Score = 27.5 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 172 RFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLV 231 V + ++++G+ R + +N+ S+R + + + Q N+ + L LV Sbjct: 47 VVVDTEVTAKKLLEKGELKRRYTIIPLNKISARCIAPETLRVAQ-NLVGPDNVHVALSLV 105 Query: 232 D 232 D Sbjct: 106 D 106 >1A7J-A nrPDB Length = 290 Score = 26.7 bits (58), Expect = 9.3, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 12/26 (46%) Query: 85 YGQTSSGKTHTMEGKLHDPQLMGIIP 110 YG+T G+T T + G+ P Sbjct: 87 YGETGQGRTRTYVHDDAEAARTGVAP 112 >3UGS-B nrPDB Length = 225 Score = 26.7 bits (58), Expect = 9.8, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 20/50 (40%), Gaps = 2/50 (4%) Query: 115 DIFDHIYSMDENLEFHIK-VSYFEIY-LDKIRDLLDVSKTNLAVHEDKNR 162 D+ + + F + SY EIY + + L + + E +NR Sbjct: 170 DLMLRVGNAKRLSNFLLWQCSYAEIYFSETLFPSLTKREFKRIIKEFRNR 219 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.159 0.510 Lambda K H 0.267 0.0485 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,862,179 Number of Sequences: 36641 Number of extensions: 462352 Number of successful extensions: 1792 Number of sequences better than 10.0: 73 Number of HSP's better than 10.0 without gapping: 114 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 1324 Number of HSP's gapped (non-prelim): 149 length of query: 239 length of database: 10,336,785 effective HSP length: 94 effective length of query: 145 effective length of database: 6,892,531 effective search space: 999416995 effective search space used: 999416995 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.7 bits)