BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P55809 (520 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3DLX-A nrPDB 989 0.0 1OOZ-A nrPDB 912 0.0 4KGB-A nrPDB 637 0.0 3RRL-A nrPDB 280 8e-76 3CDK-A nrPDB 274 8e-74 3CDK-B nrPDB 252 3e-67 3RRL-B nrPDB 242 3e-64 5DBN-B nrPDB 197 1e-50 1K6D-A nrPDB 161 5e-40 2AHV-A nrPDB 73 3e-13 6CO6-A nrPDB 51 1e-06 5MZW-A nrPDB 44 2e-04 1FMX-A nrPDB 34 0.18 4JO0-A nrPDB 31 1.0 3JB9-M nrPDB 31 1.1 2G39-A nrPDB 31 1.1 6EOT-A nrPDB 29 5.8 4XZC-A nrPDB 28 7.4 >3DLX-A nrPDB Length = 489 Score = 989 bits (2557), Expect = 0.0, Method: Compositional matrix adjust. Identities = 481/481 (100%), Positives = 481/481 (100%) Query: 40 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL 99 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL Sbjct: 2 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL 61 Query: 100 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT 159 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT Sbjct: 62 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT 121 Query: 160 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG 219 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG Sbjct: 122 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG 181 Query: 220 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI 279 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI Sbjct: 182 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI 241 Query: 280 ERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITV 339 ERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITV Sbjct: 242 ERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITV 301 Query: 340 HLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTML 399 HLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTML Sbjct: 302 HLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTML 361 Query: 400 GAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP 459 GAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP Sbjct: 362 GAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP 421 Query: 460 LTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIA 519 LTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIA Sbjct: 422 LTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIA 481 Query: 520 N 520 N Sbjct: 482 N 482 >1OOZ-A nrPDB Length = 475 Score = 912 bits (2357), Expect = 0.0, Method: Compositional matrix adjust. Identities = 440/479 (91%), Positives = 463/479 (96%), Gaps = 6/479 (1%) Query: 40 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL 99 TKFYTD VEAVKDIP+GATVLVGGFGLCGIPENLI ALLKTGVK LTAVSNNAGVDNFGL Sbjct: 1 TKFYTDAVEAVKDIPNGATVLVGGFGLCGIPENLIGALLKTGVKELTAVSNNAGVDNFGL 60 Query: 100 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT 159 GLLL+SKQIKRM+SSYVGENAEFERQYL+GELEVELTPQGTLAERIRAGGAGVPAFYT T Sbjct: 61 GLLLQSKQIKRMISSYVGENAEFERQYLAGELEVELTPQGTLAERIRAGGAGVPAFYTST 120 Query: 160 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG 219 GYGTLVQEGGSPIKYNKDGS+AIASKPREVREFNGQHFILEEAI GDFALVKAWKAD+AG Sbjct: 121 GYGTLVQEGGSPIKYNKDGSIAIASKPREVREFNGQHFILEEAIRGDFALVKAWKADQAG 180 Query: 220 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI 279 NV FRKSARNFNLPMCKAAETTVVEVEEIVDIG+FAPEDIHIP+IYVHRL+KGEKYEKRI Sbjct: 181 NVTFRKSARNFNLPMCKAAETTVVEVEEIVDIGSFAPEDIHIPKIYVHRLVKGEKYEKRI 240 Query: 280 ERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITV 339 ERLS+RKE S K GD+VRERIIKRAALEFEDGMYANLGIGIPLLASNFISPN+TV Sbjct: 241 ERLSVRKE------SGKLGDNVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNMTV 294 Query: 340 HLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTML 399 HLQSENG+LGLGPYP Q+E DADLINAGKETVT+LPGAS+FSSDESFAMIRGGHV+LTML Sbjct: 295 HLQSENGILGLGPYPLQNEVDADLINAGKETVTVLPGASYFSSDESFAMIRGGHVNLTML 354 Query: 400 GAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP 459 GAMQVSKYGDLANWMIPGK+VKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP Sbjct: 355 GAMQVSKYGDLANWMIPGKLVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP 414 Query: 460 LTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQI 518 LTGKQCVNRIITEKAVFDVD+KKGLTLIELWEGLTVDD++KSTGCDFAVSPKL+PMQQ+ Sbjct: 415 LTGKQCVNRIITEKAVFDVDRKKGLTLIELWEGLTVDDIKKSTGCDFAVSPKLIPMQQV 473 >4KGB-A nrPDB Length = 487 Score = 637 bits (1642), Expect = 0.0, Method: Compositional matrix adjust. Identities = 302/480 (62%), Positives = 382/480 (79%), Gaps = 2/480 (0%) Query: 41 KFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLG 100 K Y ++AV D+ DGA +L GGFG+CGIPE +I+AL + GVK +T VSNN GVD+ GLG Sbjct: 6 KIYESAIDAVADVQDGAQILFGGFGICGIPEKMINALKQKGVKNITGVSNNGGVDDTGLG 65 Query: 101 LLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTG 160 +L++ KQ+ +++ SYVGEN E RQYL GEL VELTPQGTLAE+IRAGGAG+PAFYTPTG Sbjct: 66 VLIKQKQVSKVIGSYVGENTELVRQYLEGELAVELTPQGTLAEKIRAGGAGIPAFYTPTG 125 Query: 161 YGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGN 220 Y TLVQEGG+PIKY+KDG V I+S+ + V+EFNG+++++EE+I DFA VKA KAD GN Sbjct: 126 YATLVQEGGAPIKYSKDGKVEISSEKKPVKEFNGKNYVMEESIFADFAFVKAQKADPLGN 185 Query: 221 VIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIE 280 ++F K+ARNFN PMC+AA+ TV EVEEIV IGA +P++IH+P IY++R+ KG Y KR+E Sbjct: 186 LVFNKAARNFNAPMCRAAKITVAEVEEIVPIGALSPDEIHVPGIYINRIFKGTNYNKRVE 245 Query: 281 RLSIRKEGD--GEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNIT 338 RL I + D A P +RERI +R ALEF DGMYANLGIGIP+L+SN+I + Sbjct: 246 RLRITEPKDPSKPAPPPNPAQVLRERIARRVALEFHDGMYANLGIGIPVLSSNYIPKGMN 305 Query: 339 VHLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTM 398 V LQSENG+LGLGP+P + + D DLINAGKE+VT++PGAS+F SD+SFAMIRGGHVD+T+ Sbjct: 306 VMLQSENGILGLGPFPTKDKVDPDLINAGKESVTVVPGASYFGSDDSFAMIRGGHVDITI 365 Query: 399 LGAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTL 458 LGAM+VS GDLANWMIPGK+VKGMGGAMDLV++ TKV++TMEH+A+ + KI++ C+L Sbjct: 366 LGAMEVSATGDLANWMIPGKLVKGMGGAMDLVAAPGTKVIITMEHNARDGSPKILDTCSL 425 Query: 459 PLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQI 518 PLTGK ++ II+EKAVF V+K GLTLIE+ EG TVDD+ STG F VSP L M QI Sbjct: 426 PLTGKGVIDMIISEKAVFTVEKGVGLTLIEVAEGYTVDDIIASTGAKFTVSPNLKKMGQI 485 >3RRL-A nrPDB Length = 235 Score = 280 bits (717), Expect = 8e-76, Method: Compositional matrix adjust. Identities = 139/247 (56%), Positives = 178/247 (72%), Gaps = 20/247 (8%) Query: 40 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL 99 K TD +A+ + DG T+LVGGFGLCGIPE ID + K G+K L VSNN GVD+FGL Sbjct: 5 NKVITDLDKALSALKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFGL 64 Query: 100 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT 159 G+LL KQIK++++SYVGEN FE Q L+GE+EV LTPQGTLAE + AGGAG+PA+YTPT Sbjct: 65 GILLEKKQIKKIIASYVGENKIFESQMLNGEIEVVLTPQGTLAENLHAGGAGIPAYYTPT 124 Query: 160 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG 219 G GTL+ +G +E REFNG+ +ILE AITGD+ L+KA+K+D G Sbjct: 125 GVGTLIAQG------------------KESREFNGKEYILERAITGDYGLIKAYKSDTLG 166 Query: 220 NVIFRKSARNFNLPMCK-AAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKR 278 N++FRK+ARNFN P+C AA+ V EVEEIV G P++IH+P IYV + KGEK+EKR Sbjct: 167 NLVFRKTARNFN-PLCAMAAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKR 225 Query: 279 IERLSIR 285 IE+++ R Sbjct: 226 IEKITTR 232 >3CDK-A nrPDB Length = 241 Score = 274 bits (700), Expect = 8e-74, Method: Compositional matrix adjust. Identities = 141/254 (55%), Positives = 174/254 (68%), Gaps = 19/254 (7%) Query: 41 KFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLG 100 K + EA K I DG T++ GGFGLCGIPE LI ++ GVK LT VSNN GVD++GLG Sbjct: 6 KVLSSSKEAAKLIHDGDTLIAGGFGLCGIPEQLILSIRDQGVKDLTVVSNNCGVDDWGLG 65 Query: 101 LLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTG 160 LLL +KQIK+M++SYVGEN FERQ+LSGELEVEL PQGTLAERIRAGGAG+P FYT TG Sbjct: 66 LLLANKQIKKMIASYVGENKIFERQFLSGELEVELVPQGTLAERIRAGGAGIPGFYTATG 125 Query: 161 YGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGN 220 GT + EG +E + F G+ ++LE ITGD A+VKAWKAD GN Sbjct: 126 VGTSIAEG------------------KEHKTFGGRTYVLERGITGDVAIVKAWKADTMGN 167 Query: 221 VIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIE 280 +IFRK+ARNFN A + T+ E EEIV+ G P+ IH P IYV ++ G EKRIE Sbjct: 168 LIFRKTARNFNPIAAMAGKITIAEAEEIVEAGELDPDHIHTPGIYVQHVVLGASQEKRIE 227 Query: 281 RLSIRK-EGDGEAK 293 + ++++ G GEAK Sbjct: 228 KRTVQQASGKGEAK 241 >3CDK-B nrPDB Length = 219 Score = 252 bits (643), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 124/214 (57%), Positives = 163/214 (76%), Gaps = 2/214 (0%) Query: 300 DVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEA 359 + R+R++KRA E +DGM NLGIG+P L +N I + V LQSENG+LG+GPYP + Sbjct: 6 EARKRMVKRAVQEIKDGMNVNLGIGMPTLVANEIPDGVHVMLQSENGLLGIGPYPLEGTE 65 Query: 360 DADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKM 419 DADLINAGKET+T + GAS+F S ESFAMIRGGH+DL +LG M+VS+ GDLANWMIPGKM Sbjct: 66 DADLINAGKETITEVTGASYFDSAESFAMIRGGHIDLAILGGMEVSEQGDLANWMIPGKM 125 Query: 420 VKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVD 479 VKGMGGAMDLV+ AK ++VV MEH K K+ + C+LPLTG++ V+R+IT+ AVFD Sbjct: 126 VKGMGGAMDLVNGAK-RIVVIMEHVNKHGESKVKKTCSLPLTGQKVVHRLITDLAVFDFV 184 Query: 480 KKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLM 513 + +TL EL +G+T+++V + T DFAVS ++ Sbjct: 185 NGR-MTLTELQDGVTIEEVYEKTEADFAVSQSVL 217 >3RRL-B nrPDB Length = 207 Score = 242 bits (617), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 119/208 (57%), Positives = 159/208 (76%), Gaps = 3/208 (1%) Query: 301 VRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEAD 360 +RE IIKRAA E ++GMY NLGIG+P L +N +S + + QSENG+LG+G YP + D Sbjct: 1 MREAIIKRAAKELKEGMYVNLGIGLPTLVANEVS-GMNIVFQSENGLLGIGAYPLEGSVD 59 Query: 361 ADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMV 420 ADLINAGKET+T++PGASFF+S +SFAMIRGGH+DL +LG M+VS+ GDLANWMIP K++ Sbjct: 60 ADLINAGKETITVVPGASFFNSADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLI 119 Query: 421 KGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDK 480 KGMGGAMDLV AK KV+V MEH K K+ ++C+LPLTGK V+++IT+ AVF+ Sbjct: 120 KGMGGAMDLVHGAK-KVIVIMEHCNKYGESKVKKECSLPLTGKGVVHQLITDLAVFEFS- 177 Query: 481 KKGLTLIELWEGLTVDDVQKSTGCDFAV 508 + L+EL EG+++D V++ T +F V Sbjct: 178 NNAMKLVELQEGVSLDQVKEKTEAEFEV 205 >5DBN-B nrPDB Length = 223 Score = 197 bits (500), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 101/214 (47%), Positives = 141/214 (65%), Gaps = 7/214 (3%) Query: 300 DVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEA 359 D ++RI +R A E DG NLGIG+P + +N++ I + LQSENG LGLGP H Sbjct: 2 DAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTTAHP- 60 Query: 360 DADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKM 419 DL+NAG + +LPGA+ F S SFA+IRGGH+D +LG +QV + +LANW++PGKM Sbjct: 61 --DLVNAGGQPCGVLPGAAMFDSAMSFALIRGGHIDACVLGGLQVDEEANLANWVVPGKM 118 Query: 420 VKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFD-V 478 V GMGGAMDLV+ ++ KV++ MEH AK + KI+ +CT+PLT + V+ ++TE AVF + Sbjct: 119 VPGMGGAMDLVTGSR-KVIIAMEHCAKDGSAKILRRCTMPLTAQHAVHMLVTELAVFRFI 177 Query: 479 DKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKL 512 D K LT E+ +G + V+ T F V+ L Sbjct: 178 DGKMWLT--EIADGCDLATVRAKTEARFEVAADL 209 >1K6D-A nrPDB Length = 220 Score = 161 bits (408), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 81/220 (36%), Positives = 136/220 (61%), Gaps = 18/220 (8%) Query: 55 DGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSS 114 DG T++VGGF G P L++ALL++GV+ LT ++N+ + G+G L+ + +++++++S Sbjct: 17 DGMTIMVGGFMGIGTPSRLVEALLESGVRDLTLIANDTAFVDTGIGPLIVNGRVRKVIAS 76 Query: 115 YVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKY 174 ++G N E R+ +SGE++V L PQGTL E+IR GGAG+ F TPTG GT+V+EG Sbjct: 77 HIGTNPETGRRMISGEMDVVLVPQGTLIEQIRCGGAGLGGFLTPTGVGTVVEEG------ 130 Query: 175 NKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPM 234 ++ +G+ ++LE + D AL++A + D GN+ ++ SARNFN + Sbjct: 131 ------------KQTLTLDGKTWLLERPLRADLALIRAHRCDTLGNLTYQLSARNFNPLI 178 Query: 235 CKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEK 274 AA+ T+VE +E+V+ G P+ I P + +I ++ Sbjct: 179 ALAADITLVEPDELVETGELQPDHIVTPGAVIDHIIVSQE 218 >2AHV-A nrPDB Length = 531 Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 132/541 (24%), Positives = 216/541 (39%), Gaps = 117/541 (21%) Query: 48 EAVKDIPDGATVLVGGFGLCGIPE--NLIDALLK-----TGVKGLTAVSNNAGVD--NFG 98 EAV IPD AT+ V G G GI E LI AL + L+ +S D + G Sbjct: 20 EAVNYIPDEATLCVLGAG-GGILEATTLITALADKYKQTQTPRNLSIISPTGLGDRADRG 78 Query: 99 LGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTP 158 + L + +K + + G++ ++ PQG L + +RA A P + Sbjct: 79 ISPLAQEGLVKWALCGHWGQSPRISDLAEQNKIIAYNYPQGVLTQTLRAAAAHQPGIISD 138 Query: 159 TGYGTLV---QEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKA 215 G GT V Q+GG + K+ + + EF+ + ++ +AI D A ++A Sbjct: 139 IGIGTFVDPRQQGGKLNEVTKEDLIKLV-------EFDNKEYLYYKAIAPDIAFIRATTC 191 Query: 216 DRAGNVIFRKSARNFN-LPMCKAAET----TVVEVEEIVDIGAFAPEDIHIP-------- 262 D G F + L + +A +++V+++V P+ + IP Sbjct: 192 DSEGYATFEDEVMYLDALVIAQAVHNNGGIVMMQVQKMVKKATLHPKSVRIPGYLVDIVV 251 Query: 263 ------QIY----VHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDDVRERIIKRAALE 312 Q+Y V+R I G+ +LS+ + R+ + +RA E Sbjct: 252 VDPDQSQLYGGAPVNRFISGDFTLDDSTKLSLPL-------------NQRKLVARRALFE 298 Query: 313 FEDGMYANLGIGIPL----------LASNFISPNITVHLQSENGVLGLGPYPRQHEADAD 362 G N+G+GI A +FI +TV G+ G Sbjct: 299 MRKGAVGNVGVGIADGIGLVAREEGCADDFI---LTVETGPIGGITSQGI---------- 345 Query: 363 LINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMVKG 422 A T IL S F GG +D+ L +V ++G++ GK++ G Sbjct: 346 AFGANVNTRAILDMTS------QFDFYHGGGLDVCYLSFAEVDQHGNVGVHKFNGKIM-G 398 Query: 423 MGGAMDLVSSAKTKVVVTMEHSA----------------KGNAHK-IMEKCTLPLTGKQC 465 GG +D+ +++K K++ +A +G K I E + +GK Sbjct: 399 TGGFIDISATSK-KIIFCGTLTAGSLKTEIADGKLNIVQEGRVKKFIRELPEITFSGKIA 457 Query: 466 VN-----RIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKST--GCDF--AVSPKLMPMQ 516 + R ITE+AVF + K+ GL LIE+ G+ D+QK DF +SP+L M Sbjct: 458 LERGLDVRYITERAVFTL-KEDGLHLIEIAPGV---DLQKDILDKMDFTPVISPELKLMD 513 Query: 517 Q 517 + Sbjct: 514 E 514 >6CO6-A nrPDB Length = 308 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 54/209 (25%), Positives = 90/209 (43%), Gaps = 17/209 (8%) Query: 48 EAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQ 107 +AV ++ G T+ +GG+G P L+ ALL++ V LT V+ G D LGLL + + Sbjct: 25 DAVGELRSGMTIGIGGWGSRRKPMALVRALLRSDVTDLTVVTYG-GPD---LGLLCSAGK 80 Query: 108 IKRMVSSYVGENAE------FERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGY 161 + + +V ++ F + +GE+ V +G + + A A +P + P Sbjct: 81 VTKAYYGFVSLDSAPFYDPWFAKARTAGEIAVREMDEGMVKCGLEAAAARLP--FLPIRA 138 Query: 162 GTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNV 221 G GS ++ + + P + I A+ D ALV D+ GN Sbjct: 139 GL-----GSDVRRFWGDELRTVTSPYPDASGKSETLIAMPALNLDAALVHLNLGDKHGNA 193 Query: 222 IFRKSARNFNLPMCKAAETTVVEVEEIVD 250 + F+ C AAE V VE +V+ Sbjct: 194 AYTGVDPYFDDLYCAAAEKRFVSVERVVE 222 >5MZW-A nrPDB Length = 265 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 58/214 (27%), Positives = 78/214 (36%), Gaps = 35/214 (16%) Query: 48 EAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVK--GLTAVSNNAGVDNFGLGLLLRS 105 EAV IPDGA++ GGF L P L+ L+ G + GL ++ N + G L Sbjct: 11 EAVASIPDGASLATGGFMLGRAPMALVMELIAQGKRDLGLISLPNPLPAEFLVAGGCLAR 70 Query: 106 KQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLA----------ERIRAGGAGVPAF 155 +I S G L +E QGTLA +R+RA G+P Sbjct: 71 LEIAFGALSLQGRVRPM--PCLKRAME-----QGTLAWREHDGYRVVQRLRAASMGLPFI 123 Query: 156 YTPTGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKA 215 P + G P F G +E A D AL+ A A Sbjct: 124 PAPDA--------------DVSGLARTEPPPTVEDPFTGLRVAVEPAFYPDVALLHARAA 169 Query: 216 DRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIV 249 D GN+ +L + AA + VEE V Sbjct: 170 DERGNLYMEDP--TTDLLVAGAAARVIATVEERV 201 >1FMX-A nrPDB Length = 329 Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust. Identities = 26/75 (34%), Positives = 31/75 (41%), Gaps = 5/75 (6%) Query: 68 GIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYL 127 G P +L TG L SN G L L SK SSY EF QY Sbjct: 22 GTPPQNFKVILDTGSSNLWVPSNECG----SLACFLHSKYDHEASSSYKANGTEFAIQYG 77 Query: 128 SGELEVELTPQGTLA 142 +G LE ++ Q TL+ Sbjct: 78 TGSLEGYIS-QDTLS 91 >4JO0-A nrPDB Length = 534 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 31/98 (31%), Positives = 38/98 (38%), Gaps = 24/98 (24%) Query: 25 YKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGV-- 82 Y G C F+ HR T F DPV + P GA F +PE ID LL T Sbjct: 257 YVGHACVFAR--HRGTTFLVDPVLSYSGYPGGAE---NRFTFADLPER-IDHLLITHNHQ 310 Query: 83 ----------------KGLTAVSNNAGVDNFGLGLLLR 104 + L S NA + + GLG +LR Sbjct: 311 DHMLFETLLRIRHRVGRVLVPKSTNASLVDPGLGGILR 348 >3JB9-M nrPDB Length = 557 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 1/92 (1%) Query: 367 GKETVTILPGASFFSSDESFAMIRGGHVDLTMLGA-MQVSKYGDLANWMIPGKMVKGMGG 425 +E +ILP F +E + H D +G + YG W G GG Sbjct: 5 SEELSSILPNPDFDDEEEDYVERETSHADERQIGVKFHIPPYGQRKGWFPSSPEDFGDGG 64 Query: 426 AMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCT 457 A + A+ + + + SAK + + + T Sbjct: 65 AFPEIHVAQYPLDMGRKRSAKSAGNTLALQVT 96 >2G39-A nrPDB Length = 497 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/79 (24%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Query: 401 AMQVSKYGDLANWMIPG-KMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP 459 A++ YG++ + + G KM+ G+GG+ D +A + VT + GN ++ + Sbjct: 357 ALEFDIYGNVNSTHVGGTKMMNGIGGSGDFARNAHLAIFVTKSIAKGGNISSVVPMVSHV 416 Query: 460 LTGKQCVNRIITEKAVFDV 478 + V+ ++TE+ + D+ Sbjct: 417 DHTEHDVDILVTEQGLADL 435 >6EOT-A nrPDB Length = 898 Score = 28.9 bits (63), Expect = 5.8, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 21/38 (55%) Query: 141 LAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDG 178 L ER R G G+ ++ G GT + + GS I + KDG Sbjct: 155 LRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDG 192 >4XZC-A nrPDB Length = 483 Score = 28.5 bits (62), Expect = 7.4, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 441 MEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQK 500 ME+ K N K ++ P K + ++T A F D L++ E+ GL DD +K Sbjct: 1 MENQIKANTKKEYDEWFKPYAEKTHLKSVLTNSASF-CDALPDLSIFEVKMGLATDDREK 59 Query: 501 ST 502 + Sbjct: 60 DS 61 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3DLX-A nrPDB 736 0.0 1OOZ-A nrPDB 709 0.0 4KGB-A nrPDB 651 0.0 2AHV-A nrPDB 405 e-113 3RRL-A nrPDB 309 1e-84 3CDK-B nrPDB 309 2e-84 3CDK-A nrPDB 302 2e-82 3RRL-B nrPDB 296 1e-80 5DBN-B nrPDB 289 2e-78 1K6D-A nrPDB 251 8e-67 6CO6-A nrPDB 208 6e-54 5MZW-A nrPDB 177 1e-44 Sequences not found previously or not previously below threshold: 6CON-A nrPDB 179 3e-45 1POI-A nrPDB 89 6e-18 1POI-B nrPDB 54 1e-07 3GK7-A nrPDB 50 2e-06 3EH7-A nrPDB 50 2e-06 3D3U-A nrPDB 48 9e-06 2HJ0-A nrPDB 44 1e-04 1XR4-A nrPDB 43 3e-04 2OAS-A nrPDB 39 0.004 2G39-A nrPDB 35 0.084 5VVW-A nrPDB 34 0.14 5N1Q-B nrPDB 34 0.15 3B0X-A nrPDB 32 0.51 2DZD-A nrPDB 32 0.71 4OTD-A nrPDB 31 1.2 4CRS-A nrPDB 31 1.4 5MDH-A nrPDB 30 2.5 1H76-A nrPDB 29 4.1 6DVI-A nrPDB 29 4.9 3RV0-A nrPDB 29 5.1 5TWA-A nrPDB 29 5.4 1TQY-A nrPDB 29 7.3 >3DLX-A nrPDB Length = 489 Score = 736 bits (1899), Expect = 0.0, Method: Composition-based stats. Identities = 481/481 (100%), Positives = 481/481 (100%) Query: 40 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL 99 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL Sbjct: 2 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL 61 Query: 100 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT 159 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT Sbjct: 62 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT 121 Query: 160 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG 219 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG Sbjct: 122 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG 181 Query: 220 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI 279 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI Sbjct: 182 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI 241 Query: 280 ERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITV 339 ERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITV Sbjct: 242 ERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITV 301 Query: 340 HLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTML 399 HLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTML Sbjct: 302 HLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTML 361 Query: 400 GAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP 459 GAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP Sbjct: 362 GAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP 421 Query: 460 LTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIA 519 LTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIA Sbjct: 422 LTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIA 481 Query: 520 N 520 N Sbjct: 482 N 482 >1OOZ-A nrPDB Length = 475 Score = 709 bits (1830), Expect = 0.0, Method: Composition-based stats. Identities = 440/479 (91%), Positives = 463/479 (96%), Gaps = 6/479 (1%) Query: 40 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL 99 TKFYTD VEAVKDIP+GATVLVGGFGLCGIPENLI ALLKTGVK LTAVSNNAGVDNFGL Sbjct: 1 TKFYTDAVEAVKDIPNGATVLVGGFGLCGIPENLIGALLKTGVKELTAVSNNAGVDNFGL 60 Query: 100 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT 159 GLLL+SKQIKRM+SSYVGENAEFERQYL+GELEVELTPQGTLAERIRAGGAGVPAFYT T Sbjct: 61 GLLLQSKQIKRMISSYVGENAEFERQYLAGELEVELTPQGTLAERIRAGGAGVPAFYTST 120 Query: 160 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG 219 GYGTLVQEGGSPIKYNKDGS+AIASKPREVREFNGQHFILEEAI GDFALVKAWKAD+AG Sbjct: 121 GYGTLVQEGGSPIKYNKDGSIAIASKPREVREFNGQHFILEEAIRGDFALVKAWKADQAG 180 Query: 220 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI 279 NV FRKSARNFNLPMCKAAETTVVEVEEIVDIG+FAPEDIHIP+IYVHRL+KGEKYEKRI Sbjct: 181 NVTFRKSARNFNLPMCKAAETTVVEVEEIVDIGSFAPEDIHIPKIYVHRLVKGEKYEKRI 240 Query: 280 ERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITV 339 ERLS+RKE S K GD+VRERIIKRAALEFEDGMYANLGIGIPLLASNFISPN+TV Sbjct: 241 ERLSVRKE------SGKLGDNVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNMTV 294 Query: 340 HLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTML 399 HLQSENG+LGLGPYP Q+E DADLINAGKETVT+LPGAS+FSSDESFAMIRGGHV+LTML Sbjct: 295 HLQSENGILGLGPYPLQNEVDADLINAGKETVTVLPGASYFSSDESFAMIRGGHVNLTML 354 Query: 400 GAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP 459 GAMQVSKYGDLANWMIPGK+VKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP Sbjct: 355 GAMQVSKYGDLANWMIPGKLVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLP 414 Query: 460 LTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQI 518 LTGKQCVNRIITEKAVFDVD+KKGLTLIELWEGLTVDD++KSTGCDFAVSPKL+PMQQ+ Sbjct: 415 LTGKQCVNRIITEKAVFDVDRKKGLTLIELWEGLTVDDIKKSTGCDFAVSPKLIPMQQV 473 >4KGB-A nrPDB Length = 487 Score = 651 bits (1678), Expect = 0.0, Method: Composition-based stats. Identities = 301/480 (62%), Positives = 382/480 (79%), Gaps = 2/480 (0%) Query: 41 KFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLG 100 K Y ++AV D+ DGA +L GGFG+CGIPE +I+AL + GVK +T VSNN GVD+ GLG Sbjct: 6 KIYESAIDAVADVQDGAQILFGGFGICGIPEKMINALKQKGVKNITGVSNNGGVDDTGLG 65 Query: 101 LLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTG 160 +L++ KQ+ +++ SYVGEN E RQYL GEL VELTPQGTLAE+IRAGGAG+PAFYTPTG Sbjct: 66 VLIKQKQVSKVIGSYVGENTELVRQYLEGELAVELTPQGTLAEKIRAGGAGIPAFYTPTG 125 Query: 161 YGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGN 220 Y TLVQEGG+PIKY+KDG V I+S+ + V+EFNG+++++EE+I DFA VKA KAD GN Sbjct: 126 YATLVQEGGAPIKYSKDGKVEISSEKKPVKEFNGKNYVMEESIFADFAFVKAQKADPLGN 185 Query: 221 VIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIE 280 ++F K+ARNFN PMC+AA+ TV EVEEIV IGA +P++IH+P IY++R+ KG Y KR+E Sbjct: 186 LVFNKAARNFNAPMCRAAKITVAEVEEIVPIGALSPDEIHVPGIYINRIFKGTNYNKRVE 245 Query: 281 RLSIRKEGDGEAKSAKP--GDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNIT 338 RL I + D + P +RERI +R ALEF DGMYANLGIGIP+L+SN+I + Sbjct: 246 RLRITEPKDPSKPAPPPNPAQVLRERIARRVALEFHDGMYANLGIGIPVLSSNYIPKGMN 305 Query: 339 VHLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTM 398 V LQSENG+LGLGP+P + + D DLINAGKE+VT++PGAS+F SD+SFAMIRGGHVD+T+ Sbjct: 306 VMLQSENGILGLGPFPTKDKVDPDLINAGKESVTVVPGASYFGSDDSFAMIRGGHVDITI 365 Query: 399 LGAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTL 458 LGAM+VS GDLANWMIPGK+VKGMGGAMDLV++ TKV++TMEH+A+ + KI++ C+L Sbjct: 366 LGAMEVSATGDLANWMIPGKLVKGMGGAMDLVAAPGTKVIITMEHNARDGSPKILDTCSL 425 Query: 459 PLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQI 518 PLTGK ++ II+EKAVF V+K GLTLIE+ EG TVDD+ STG F VSP L M QI Sbjct: 426 PLTGKGVIDMIISEKAVFTVEKGVGLTLIEVAEGYTVDDIIASTGAKFTVSPNLKKMGQI 485 >2AHV-A nrPDB Length = 531 Score = 405 bits (1041), Expect = e-113, Method: Composition-based stats. Identities = 131/544 (24%), Positives = 215/544 (39%), Gaps = 117/544 (21%) Query: 45 DPVEAVKDIPDGATVLVGGFGLCGIPEN--LIDALLK-----TGVKGLTAVSNNAGVD-- 95 EAV IPD AT+ V G G GI E LI AL + L+ +S D Sbjct: 17 SAQEAVNYIPDEATLCVLGAG-GGILEATTLITALADKYKQTQTPRNLSIISPTGLGDRA 75 Query: 96 NFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAF 155 + G+ L + +K + + G++ ++ PQG L + +RA A P Sbjct: 76 DRGISPLAQEGLVKWALCGHWGQSPRISDLAEQNKIIAYNYPQGVLTQTLRAAAAHQPGI 135 Query: 156 YTPTGYGTLV---QEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKA 212 + G GT V Q+GG + K+ + + EF+ + ++ +AI D A ++A Sbjct: 136 ISDIGIGTFVDPRQQGGKLNEVTKEDLIKLV-------EFDNKEYLYYKAIAPDIAFIRA 188 Query: 213 WKADRAGNVIFRKSARNFN-LPMCKAAE----TTVVEVEEIVDIGAFAPEDIHIPQ---- 263 D G F + L + +A +++V+++V P+ + IP Sbjct: 189 TTCDSEGYATFEDEVMYLDALVIAQAVHNNGGIVMMQVQKMVKKATLHPKSVRIPGYLVD 248 Query: 264 ----------IY----VHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDDVRERIIKRA 309 +Y V+R I G+ +LS+ + R+ + +RA Sbjct: 249 IVVVDPDQSQLYGGAPVNRFISGDFTLDDSTKLSLPL-------------NQRKLVARRA 295 Query: 310 ALEFEDGMYANLGIGIPL----------LASNFISPNITVHLQSENGVLGLGPYPRQHEA 359 E G N+G+GI A +FI +TV G+ G Sbjct: 296 LFEMRKGAVGNVGVGIADGIGLVAREEGCADDFI---LTVETGPIGGITSQGI------- 345 Query: 360 DADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKM 419 A T IL S F GG +D+ L +V ++G++ GK+ Sbjct: 346 ---AFGANVNTRAILDMTS------QFDFYHGGGLDVCYLSFAEVDQHGNVGVHKFNGKI 396 Query: 420 VKGMGGAMDLVSSAKTKVVVTMEHSA----------------KGNAHK-IMEKCTLPLTG 462 + G GG +D+ +++K K++ +A +G K I E + +G Sbjct: 397 M-GTGGFIDISATSK-KIIFCGTLTAGSLKTEIADGKLNIVQEGRVKKFIRELPEITFSG 454 Query: 463 KQCVN-----RIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKST--GCDF--AVSPKLM 513 K + R ITE+AVF + K+ GL LIE+ G+ D+QK DF +SP+L Sbjct: 455 KIALERGLDVRYITERAVFTL-KEDGLHLIEIAPGV---DLQKDILDKMDFTPVISPELK 510 Query: 514 PMQQ 517 M + Sbjct: 511 LMDE 514 >3RRL-A nrPDB Length = 235 Score = 309 bits (792), Expect = 1e-84, Method: Composition-based stats. Identities = 137/249 (55%), Positives = 175/249 (70%), Gaps = 18/249 (7%) Query: 40 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL 99 K TD +A+ + DG T+LVGGFGLCGIPE ID + K G+K L VSNN GVD+FGL Sbjct: 5 NKVITDLDKALSALKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFGL 64 Query: 100 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT 159 G+LL KQIK++++SYVGEN FE Q L+GE+EV LTPQGTLAE + AGGAG+PA+YTPT Sbjct: 65 GILLEKKQIKKIIASYVGENKIFESQMLNGEIEVVLTPQGTLAENLHAGGAGIPAYYTPT 124 Query: 160 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG 219 G GTL+ +G +E REFNG+ +ILE AITGD+ L+KA+K+D G Sbjct: 125 GVGTLIAQG------------------KESREFNGKEYILERAITGDYGLIKAYKSDTLG 166 Query: 220 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI 279 N++FRK+ARNFN AA+ V EVEEIV G P++IH+P IYV + KGEK+EKRI Sbjct: 167 NLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRI 226 Query: 280 ERLSIRKEG 288 E+++ R Sbjct: 227 EKITTRSTK 235 >3CDK-B nrPDB Length = 219 Score = 309 bits (791), Expect = 2e-84, Method: Composition-based stats. Identities = 124/219 (56%), Positives = 164/219 (74%), Gaps = 2/219 (0%) Query: 295 AKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYP 354 + + R+R++KRA E +DGM NLGIG+P L +N I + V LQSENG+LG+GPYP Sbjct: 1 SNAMKEARKRMVKRAVQEIKDGMNVNLGIGMPTLVANEIPDGVHVMLQSENGLLGIGPYP 60 Query: 355 RQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWM 414 + DADLINAGKET+T + GAS+F S ESFAMIRGGH+DL +LG M+VS+ GDLANWM Sbjct: 61 LEGTEDADLINAGKETITEVTGASYFDSAESFAMIRGGHIDLAILGGMEVSEQGDLANWM 120 Query: 415 IPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKA 474 IPGKMVKGMGGAMDLV+ AK ++VV MEH K K+ + C+LPLTG++ V+R+IT+ A Sbjct: 121 IPGKMVKGMGGAMDLVNGAK-RIVVIMEHVNKHGESKVKKTCSLPLTGQKVVHRLITDLA 179 Query: 475 VFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLM 513 VFD + +TL EL +G+T+++V + T DFAVS ++ Sbjct: 180 VFDFVNGR-MTLTELQDGVTIEEVYEKTEADFAVSQSVL 217 >3CDK-A nrPDB Length = 241 Score = 302 bits (773), Expect = 2e-82, Method: Composition-based stats. Identities = 141/254 (55%), Positives = 174/254 (68%), Gaps = 19/254 (7%) Query: 41 KFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLG 100 K + EA K I DG T++ GGFGLCGIPE LI ++ GVK LT VSNN GVD++GLG Sbjct: 6 KVLSSSKEAAKLIHDGDTLIAGGFGLCGIPEQLILSIRDQGVKDLTVVSNNCGVDDWGLG 65 Query: 101 LLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTG 160 LLL +KQIK+M++SYVGEN FERQ+LSGELEVEL PQGTLAERIRAGGAG+P FYT TG Sbjct: 66 LLLANKQIKKMIASYVGENKIFERQFLSGELEVELVPQGTLAERIRAGGAGIPGFYTATG 125 Query: 161 YGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGN 220 GT + EG +E + F G+ ++LE ITGD A+VKAWKAD GN Sbjct: 126 VGTSIAEG------------------KEHKTFGGRTYVLERGITGDVAIVKAWKADTMGN 167 Query: 221 VIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIE 280 +IFRK+ARNFN A + T+ E EEIV+ G P+ IH P IYV ++ G EKRIE Sbjct: 168 LIFRKTARNFNPIAAMAGKITIAEAEEIVEAGELDPDHIHTPGIYVQHVVLGASQEKRIE 227 Query: 281 RLSIRK-EGDGEAK 293 + ++++ G GEAK Sbjct: 228 KRTVQQASGKGEAK 241 >3RRL-B nrPDB Length = 207 Score = 296 bits (758), Expect = 1e-80, Method: Composition-based stats. Identities = 119/208 (57%), Positives = 159/208 (76%), Gaps = 3/208 (1%) Query: 301 VRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEAD 360 +RE IIKRAA E ++GMY NLGIG+P L +N +S + + QSENG+LG+G YP + D Sbjct: 1 MREAIIKRAAKELKEGMYVNLGIGLPTLVANEVS-GMNIVFQSENGLLGIGAYPLEGSVD 59 Query: 361 ADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMV 420 ADLINAGKET+T++PGASFF+S +SFAMIRGGH+DL +LG M+VS+ GDLANWMIP K++ Sbjct: 60 ADLINAGKETITVVPGASFFNSADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLI 119 Query: 421 KGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDK 480 KGMGGAMDLV AK KV+V MEH K K+ ++C+LPLTGK V+++IT+ AVF+ Sbjct: 120 KGMGGAMDLVHGAK-KVIVIMEHCNKYGESKVKKECSLPLTGKGVVHQLITDLAVFEFS- 177 Query: 481 KKGLTLIELWEGLTVDDVQKSTGCDFAV 508 + L+EL EG+++D V++ T +F V Sbjct: 178 NNAMKLVELQEGVSLDQVKEKTEAEFEV 205 >5DBN-B nrPDB Length = 223 Score = 289 bits (739), Expect = 2e-78, Method: Composition-based stats. Identities = 101/214 (47%), Positives = 140/214 (65%), Gaps = 7/214 (3%) Query: 300 DVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEA 359 D ++RI +R A E DG NLGIG+P + +N++ I + LQSENG LGLGP H Sbjct: 2 DAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTTAHP- 60 Query: 360 DADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKM 419 DL+NAG + +LPGA+ F S SFA+IRGGH+D +LG +QV + +LANW++PGKM Sbjct: 61 --DLVNAGGQPCGVLPGAAMFDSAMSFALIRGGHIDACVLGGLQVDEEANLANWVVPGKM 118 Query: 420 VKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDV- 478 V GMGGAMDLV+ ++ KV++ MEH AK + KI+ +CT+PLT + V+ ++TE AVF Sbjct: 119 VPGMGGAMDLVTGSR-KVIIAMEHCAKDGSAKILRRCTMPLTAQHAVHMLVTELAVFRFI 177 Query: 479 DKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKL 512 D K LT E+ +G + V+ T F V+ L Sbjct: 178 DGKMWLT--EIADGCDLATVRAKTEARFEVAADL 209 >1K6D-A nrPDB Length = 220 Score = 251 bits (640), Expect = 8e-67, Method: Composition-based stats. Identities = 85/235 (36%), Positives = 141/235 (60%), Gaps = 19/235 (8%) Query: 40 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL 99 TK T +A DG T++VGGF G P L++ALL++GV+ LT ++N+ + G+ Sbjct: 3 TKLMT-LQDATGFFRDGMTIMVGGFMGIGTPSRLVEALLESGVRDLTLIANDTAFVDTGI 61 Query: 100 GLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT 159 G L+ + +++++++S++G N E R+ +SGE++V L PQGTL E+IR GGAG+ F TPT Sbjct: 62 GPLIVNGRVRKVIASHIGTNPETGRRMISGEMDVVLVPQGTLIEQIRCGGAGLGGFLTPT 121 Query: 160 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG 219 G GT+V+EG ++ +G+ ++LE + D AL++A + D G Sbjct: 122 GVGTVVEEG------------------KQTLTLDGKTWLLERPLRADLALIRAHRCDTLG 163 Query: 220 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEK 274 N+ ++ SARNFN + AA+ T+VE +E+V+ G P+ I P + +I ++ Sbjct: 164 NLTYQLSARNFNPLIALAADITLVEPDELVETGELQPDHIVTPGAVIDHIIVSQE 218 >6CO6-A nrPDB Length = 308 Score = 208 bits (528), Expect = 6e-54, Method: Composition-based stats. Identities = 53/233 (22%), Positives = 97/233 (41%), Gaps = 18/233 (7%) Query: 45 DPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLR 104 +AV ++ G T+ +GG+G P L+ ALL++ V LT V+ LGLL Sbjct: 22 SLDDAVGELRSGMTIGIGGWGSRRKPMALVRALLRSDVTDLTVVTYGGP----DLGLLCS 77 Query: 105 SKQIKRMVSSYVGENAE------FERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTP 158 + ++ + +V ++ F + +GE+ V +G + + A A +P + P Sbjct: 78 AGKVTKAYYGFVSLDSAPFYDPWFAKARTAGEIAVREMDEGMVKCGLEAAAARLP--FLP 135 Query: 159 TGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRA 218 G GS ++ + + P + I A+ D ALV D+ Sbjct: 136 IRAGL-----GSDVRRFWGDELRTVTSPYPDASGKSETLIAMPALNLDAALVHLNLGDKH 190 Query: 219 GNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIK 271 GN + F+ C AAE V VE +V+ + + + + ++R++ Sbjct: 191 GNAAYTGVDPYFDDLYCAAAEKRFVSVERVVETEELV-KTVPLQNLILNRMMV 242 >6CON-A nrPDB Length = 305 Score = 179 bits (453), Expect = 3e-45, Method: Composition-based stats. Identities = 52/234 (22%), Positives = 89/234 (38%), Gaps = 18/234 (7%) Query: 44 TDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLL 103 T +AV + G T+ + G+G P + A+L++ V LT V+ LGLL Sbjct: 19 TALDDAVAQLRSGMTIGIAGWGSRRKPMAFVRAILRSDVTDLTVVTYGGP----DLGLLC 74 Query: 104 RSKQIKRMVSSYVGENAE------FERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYT 157 + ++KR+ +V ++ F SG +E +G L ++A +P + Sbjct: 75 SAGKVKRVYYGFVSLDSPPFYDPWFAHARTSGAIEAREMDEGMLRCGLQAAAQRLP--FL 132 Query: 158 PTGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADR 217 P G GS + G + + P + I A+ D A D Sbjct: 133 PIRAGL-----GSSVPQFWAGELQTVTSPYPAPGGGYETLIAMPALRLDAAFAHLNLGDS 187 Query: 218 AGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIK 271 GN + F+ AAE + VE IV + + + V+R++ Sbjct: 188 HGNAAYTGIDPYFDDLFLMAAERRFLSVERIVATEELV-KSVPPQALLVNRMMV 240 >5MZW-A nrPDB Length = 265 Score = 177 bits (448), Expect = 1e-44, Method: Composition-based stats. Identities = 57/233 (24%), Positives = 81/233 (34%), Gaps = 25/233 (10%) Query: 45 DPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGL--TAVSNNAGVDNFGLGLL 102 EAV IPDGA++ GGF L P L+ L+ G + L ++ N + G Sbjct: 8 SLEEAVASIPDGASLATGGFMLGRAPMALVMELIAQGKRDLGLISLPNPLPAEFLVAGGC 67 Query: 103 LRSKQIKRMVSSYVGENAEF---ERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT 159 L +I S G +R G L + +R+RA G+P P Sbjct: 68 LARLEIAFGALSLQGRVRPMPCLKRAMEQGTLAWREHDGYRVVQRLRAASMGLPFIPAPD 127 Query: 160 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAG 219 + G P F G +E A D AL+ A AD G Sbjct: 128 A--------------DVSGLARTEPPPTVEDPFTGLRVAVEPAFYPDVALLHARAADERG 173 Query: 220 NVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKG 272 N+ +L + AA + VEE V P +P V R++ Sbjct: 174 NLYMED--PTTDLLVAGAAARVIATVEERVAK---LPRAT-LPGFQVDRIVLA 220 >1POI-A nrPDB Length = 317 Score = 88.7 bits (218), Expect = 6e-18, Method: Composition-based stats. Identities = 50/244 (20%), Positives = 91/244 (37%), Gaps = 15/244 (6%) Query: 40 TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGL 99 +K T K + G + +GGF P + +L+ G+ LT + AG D Sbjct: 1 SKVMTLKDAIAKYVHSGDHIALGGFTTDRKPYAAVFEILRQGITDLTGLGGAAGGDW--- 57 Query: 100 GLLLRSKQIKRMVSSYVGE------NAEFERQYLSGELEVELTPQGTLAERIRAGGAGVP 153 +L+ + ++K ++ Y + F + + +G+L +E Q + A G+P Sbjct: 58 DMLIGNGRVKAYINCYTANSGVTNVSRRFRKWFEAGKLTMEDYSQDVIYMMWHAAALGLP 117 Query: 154 AFYTPT--GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFN-GQHFILEEAITGDFALV 210 G G + G S V F G+ + D A++ Sbjct: 118 FLPVTLMQGSGLTDEWGISKEVRKTLDKVPDDKFKYIDNPFKPGEKVVAVPVPQVDVAII 177 Query: 211 KAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAF--APEDIHIPQIYVHR 268 A +A G V + ++ + +AA+ T+V EEI+ P IP + V Sbjct: 178 HAQQASPDGTVRIWG-GKFQDVDIAEAAKYTIVTCEEIISDEEIRRDPTKNDIPGMCVDA 236 Query: 269 LIKG 272 ++ Sbjct: 237 VVLA 240 >1POI-B nrPDB Length = 260 Score = 54.4 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 45/237 (18%), Positives = 92/237 (38%), Gaps = 33/237 (13%) Query: 302 RERIIKRAALEFEDGMYANLGIGIPLLASNFI----SPNITVHLQSENGVLGLGPYPRQH 357 +E A + ++G +G G+PL+ ++ +P+ + + E+G++ P Sbjct: 8 KEMQAVTIAKQIKNGQVVTVGTGLPLIGASVAKRVYAPDCHIIV--ESGLMDCSPVEVPR 65 Query: 358 EADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDL-----AN 412 A + F E + + + +G Q+ YG++ + Sbjct: 66 SVGDLRFMAH---CGCIWPNVRFVGFEINEYLHKANRLIAFIGGAQIDPYGNVNSTSIGD 122 Query: 413 WMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKI--------------MEKCTL 458 + P G GGA + + + T ++ M+H + +KI E+ L Sbjct: 123 YHHPKTRFTGSGGANGIATYSNT--IIMMQHEKRRFMNKIDYVTSPGWIDGPGGRERLGL 180 Query: 459 PLTGKQCVNRIITEKAVFDVDKK-KGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMP 514 P G ++T+K + D+K K + L + + +DV ++TG D VS + Sbjct: 181 P--GDVGPQLVVTDKGILKFDEKTKRMYLAAYYPTSSPEDVLENTGFDLDVSKAVEL 235 >3GK7-A nrPDB Length = 448 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 63/312 (20%), Positives = 109/312 (34%), Gaps = 58/312 (18%) Query: 236 KAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSA 295 K+A+ + EV + V P +Y + + +K +E S G K Sbjct: 146 KSAKIVLAEVNDQV------------PVVYGDTFVHVSEIDKFVET-SHPLPEIGLPKIG 192 Query: 296 KPGDDVRERIIKRAALEFEDGMYANLGIG-IPLLASNFISPNITVHLQSENGVLGLGPYP 354 +V I K A EDG LGIG IP + + + + SE ++ G Sbjct: 193 ----EVEAAIGKHCASLIEDGSTLQLGIGAIPDAVLSQLKDKKHLGIHSE--MISDGVVD 246 Query: 355 RQHEADADL----INAGKETVTILPGAS-FFSSDESFAMIRGGHVD-------------- 395 D I+ GK +T L G + + + VD Sbjct: 247 LYEAGVIDCSQKSIDKGKMAITFLMGTKRLYDFAANNPKVELKPVDYINHPSVVAQCSKM 306 Query: 396 LTMLGAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSA------KTKVVVTMEHSAKGNA 449 + + +QV G + + I K G+GG +D V A K K ++ M AK Sbjct: 307 VCINACLQVDFMGQIVSDSIGTKQFSGVGGQVDFVRGASMSIDGKGKAIIAMPSVAKKKD 366 Query: 450 HKIMEKCTLPL--------TGKQCVNRIITEKAVFDVDKK----KGLTLIELWEGLTVDD 497 ++ K +P T + + ++TE + ++ K + LI + D+ Sbjct: 367 GSMISKI-VPFIDHGAAVTTSRNDADYVVTEYGIAEMKGKSLQDRARALINIAHPDFKDE 425 Query: 498 VQKSTGCDFAVS 509 ++ F + Sbjct: 426 LKAEFEKRFNAA 437 >3EH7-A nrPDB Length = 434 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 63/339 (18%), Positives = 124/339 (36%), Gaps = 58/339 (17%) Query: 203 ITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPED-IHI 261 + D A+V+ D G F + +++ P ++A + E+ + ++ IHI Sbjct: 118 LHIDVAIVQLSMPDENGYCSF-GVSCDYSKPAAESAHLVIGEINRQMPY--VHGDNLIHI 174 Query: 262 PQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANL 321 ++ ++ + S+ K GE V E I + A EDG L Sbjct: 175 SKL--DYIVMADYPI-----YSLAKPKIGE---------VEEAIGRNCAELIEDGATLQL 218 Query: 322 GIG-IPLLASNFISP----NITVHLQSEN--GVLGLGPYPRQHEADADLINAGKETVTIL 374 GIG IP A F+ I + S+ ++ G + + ++ GK T L Sbjct: 219 GIGAIPDAALLFLKDKKDLGIHTEMFSDGVVELVRSGVITGKKKT----LHPGKMVATFL 274 Query: 375 PGAS----FFSSDESFAMIRGGHVD-----------LTMLGAMQVSKYGDLANWMIPGKM 419 G+ F + + +V+ +++ +++ G + + I K Sbjct: 275 MGSEDVYHFIDKNPDVELYPVDYVNDPRVIAQNDNMVSINSCIEIDLMGQVVSECIGSKQ 334 Query: 420 VKGMGGAMDLVSSA----KTKVVVTMEHSAKGNAHK----IMEKCTLPLTGKQCVNRIIT 471 G GG +D V A K ++ + +AK I+ + T + V+ ++T Sbjct: 335 FSGTGGQVDYVRGAAWSKNGKSIMAIPSTAKNGTASRIVPIIAEGAAVTTLRNEVDYVVT 394 Query: 472 EKAVFDVDKK----KGLTLIELWEGLTVDDVQKSTGCDF 506 E + + K + LI + +++ K F Sbjct: 395 EYGIAQLKGKSLRQRAEALIAIAHPDFREELTKHLRKRF 433 >3D3U-A nrPDB Length = 439 Score = 48.2 bits (113), Expect = 9e-06, Method: Composition-based stats. Identities = 63/331 (19%), Positives = 111/331 (33%), Gaps = 62/331 (18%) Query: 198 ILEEAITG-DFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAP 256 + + D A+V+ + G F S + A V EV + + Sbjct: 109 LFRQGFFPLDVAVVQVSTPNEEGYCSFGVSCDYTKA-AAECAPVVVAEVNKQMP------ 161 Query: 257 EDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKS--AKPGDDVRERIIKRAALEFE 314 G + I +L+ E D G D+ RI + A + Sbjct: 162 -------------FIGGENLIHISKLTHIIEVDEPIAEVLPPAGSDLELRIGQNCASLIK 208 Query: 315 DGMYANLGI-GIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKETV-- 371 DG LGI GIP + + + + +E G+ R+ +IN K+T+ Sbjct: 209 DGDTLQLGIGGIPDAVLRALEGHKDLGIHTEMFTDGVMRMIRKG-----IINGKKKTLHP 263 Query: 372 TILPGASFFSSDESFAMIRGGHVDLTML--------------------GAMQVSKYGDLA 411 + + F S E + + V +++ G A Sbjct: 264 EKVVTSLIFGSKELYDFVNNNPVIECYPVDYINNPDVIGKNDRMVSINSCLEMDLMGQAA 323 Query: 412 NWMIPGKMVKGMGGAMDLVSSAKTK----VVVTMEHSAKGNAHK----IMEKCTLPLTGK 463 + I + G GG +D + AK ++ +AK I+++ TG+ Sbjct: 324 SESIGYEQFSGSGGQVDFLRGAKRSKGGISIMAFPSTAKKGTESRIVPILKEGACVTTGR 383 Query: 464 QCVNRIITEKAVFDVDKKKGLTLIELWEGLT 494 V+ ++TE V + +G TL + E LT Sbjct: 384 NEVDYVVTEYGVARL---RGATLRQRAEALT 411 >2HJ0-A nrPDB Length = 519 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 65/349 (18%), Positives = 120/349 (34%), Gaps = 50/349 (14%) Query: 160 GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQ-HFILEEAITGDFALVKAWKADRA 218 G T + G K S I P +R G+ I + I D A + A +D Sbjct: 116 GVVTNITSSGLRDKVGAAISEGIMENPVIIRSHGGRARAIATDDIHIDVAFLGAPSSDAY 175 Query: 219 GNVIFRKSARN-----FNLPMCKAAETTVVEVEEIVDIGAFAPED-IHIPQIYVHRLIKG 272 GN + + + K A+ V+ + +V P I IPQ V ++ Sbjct: 176 GNANGTRGKTTCGSLGYAMIDAKYADQVVIVTDTLVP----YPNTPISIPQTDVDYIVVV 231 Query: 273 EKYEKRIERLSIRKEGDGEAKSAKPGDDVRERIIKRAALE-------FEDGMYANLGIGI 325 + +I + + + +E +I A + +++G G G Sbjct: 232 D---------AIGDPEGIAKGATRYTKNPKELLIAEYAAKVITSSPYYKEGFSFQTGTGG 282 Query: 326 PLLA---------------SNFISPNIT---VHLQSENGVLGLGPYPRQHEADADLINAG 367 LA +NF IT V L E V + A ++ Sbjct: 283 ASLAVTRFMREQMIKDDIKANFALGGITNAMVELLEEGLVDKILDVQDFDHPSAVSLDRN 342 Query: 368 KETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMVKG-MGGA 426 E + + S ++I +D+ +L A++V ++ +++G GG Sbjct: 343 AEKHYEIDANMYASPLSKGSVIN--QLDICVLSALEVDTNFNVNVMTGSDGVIRGASGGH 400 Query: 427 MDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAV 475 D +AK +V+ +G ++K +T V+ ++TE + Sbjct: 401 CDTAFAAKMSLVI--SPLVRGRIPTFVDKVNTVITPGTSVDVVVTEVGI 447 >1XR4-A nrPDB Length = 509 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 83/482 (17%), Positives = 162/482 (33%), Gaps = 113/482 (23%) Query: 33 STSAHRHTKFYTDPVEAV--KDIPDGATVLVG-GFGLCGIPENLIDA-LLKTGVKGLTAV 88 S + R K EA+ + +G T+ F N++ A L + G + LT Sbjct: 36 SETEKRRRKICDSLEEAIRRSGLKNGMTISFHHAFRGGDKVVNMVMAKLAEMGFRDLTLA 95 Query: 89 SNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAG 148 S++ ++ L +++ ++++ +S + +G L E I AG Sbjct: 96 SSSLIDAHWPLIEHIKNGVVRQIYTSGL---------------------RGKLGEEISAG 134 Query: 149 GAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFA 208 P + G +K + G + I D A Sbjct: 135 LMENP---------VQIHSHGGRVKLIQSGELNI-----------------------DVA 162 Query: 209 LVKAWKADRAGNVI-FRKSARNFNLPMCKA----AETTVVEVEEIVDIGAFAPEDIHIPQ 263 + D GN F +R +L + A+ V+ EE V+ + P I Q Sbjct: 163 FLGVPCCDEFGNANGFSGKSRCGSLGYAQVDAQYAKCVVLLTEEWVEFPNY-PASIAQDQ 221 Query: 264 IYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDDVRERIIKRAALE-------FEDG 316 V +++ ++ A + + + RE +I R A F DG Sbjct: 222 --VDLIVQVDEVGD---------PEKITAGAIRLSSNPRELLIARQAANVIEHSGYFCDG 270 Query: 317 MYANLGIGIPLLA-SNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKETVTILP 375 G G LA + F+ + H + + LG + LI A +T + Sbjct: 271 FSLQTGTGGASLAVTRFLEDKMRRHNITASFGLGGITGTMVDLHEKGLIKALLDTQS--- 327 Query: 376 GASFFSSDESFAMIRGGH---------------------VDLTMLGAMQVSKYGDLANWM 414 F D + ++ + H +++ ML A+++ ++ Sbjct: 328 ----FDGDAARSLAQNPHHIEISTNQYANPASKGAACERLNVVMLSALEIDVNFNVNVMT 383 Query: 415 IPGKMVKG-MGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEK 473 +++G GG D + A ++ +G ++EK +T V+ ++T+ Sbjct: 384 GSNGVLRGASGGHSDTAAGADLTIITA--PLVRGRIPCVVEKVLTTVTPGASVDVLVTDH 441 Query: 474 AV 475 + Sbjct: 442 GI 443 >2OAS-A nrPDB Length = 436 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 58/321 (18%), Positives = 102/321 (31%), Gaps = 60/321 (18%) Query: 206 DFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQ-- 263 D A+++ D+ G S L C+ A + + P+ Sbjct: 112 DTAIIQVSPPDKHGMCSLGISVEAT-LAACQVAGKIIAHI---------NPQMPRTHGDG 161 Query: 264 -IYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLG 322 I++ R YE + S GD V I + A DG +G Sbjct: 162 FIHIDRF--AAVYE---------QSASLPIHSFATGDAVSLAIGQHVAELVRDGDCLQMG 210 Query: 323 IG-IPL----LASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGA 377 IG IP + + L S+ G+L L + T L Sbjct: 211 IGAIPDAVLSCLTGHKDLGVHTELFSD-GILQLVEKGVINNTKKRFYPGKLVTGFALGSQ 269 Query: 378 SFFSSDES--------------FAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMVKGM 423 + + ++IR + + A+QV G + I K+ G+ Sbjct: 270 KLYDYVDDNPAVIFMDIEQVNDTSIIRKNPNVMAINSALQVDLTGQVCADSIGTKIYSGV 329 Query: 424 GGAMDLVSSA----KTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQC------VNRIITEK 473 GG MD + A + V+ + +A G +I ++ G V+ I+TE Sbjct: 330 GGQMDFIRGAGLSEGGRSVIALPSTAAGG--RISRIASVLSPGAGVVTTRAHVHYIVTEY 387 Query: 474 AVFDVD----KKKGLTLIELW 490 ++ +++ LI + Sbjct: 388 GAANLKGRSLRERAQALINIA 408 >2G39-A nrPDB Length = 497 Score = 35.1 bits (79), Expect = 0.084, Method: Composition-based stats. Identities = 87/482 (18%), Positives = 160/482 (33%), Gaps = 107/482 (22%) Query: 45 DPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLR 104 EA I DG TV + GF G + + AL + +S G Sbjct: 17 SAAEAADLIQDGMTVGMSGFTRAGEAKAVPQALAMRAKERPLRISLMTGAS--------- 67 Query: 105 SKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTL 164 L +L+ +LT G LA R+ P + Sbjct: 68 ----------------------LGNDLDKQLTEAGVLARRM------------PFQVDST 93 Query: 165 VQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFR 224 +++ + + + V + L D A+++A G+++ Sbjct: 94 LRKAINAGEVMFIDQHLSET----VEQLRNHQLKL-----PDIAVIEAAAITEQGHIVPT 144 Query: 225 KSARNFNLPMCKAAETTVVEVE----------EIVDIGAFAPEDIHIPQIYVHRLIKGEK 274 S N + A+ +VE+ + I + P IP V I Sbjct: 145 TSVGN-SASFAIFAKQVIVEINLAHSTNLEGLHDIYIPTYRPTRTPIPLTRVDDRIGSTA 203 Query: 275 YEKRIERLSIRKEGDGEAKSAK--PGDDVRERIIKRAA----LEFEDGMYAN------LG 322 E++ D + P D + I E + G +N G Sbjct: 204 IPIPPEKIVAIVINDQPDSPSTVLPPDGETQAIANHLIDFFKREVDAGRMSNSLGPLQAG 263 Query: 323 IGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGK------ETVTILP- 375 IG +N + + + EN L + Q DLI+AGK ++T+ P Sbjct: 264 IG---SIANAVMCGL-IESPFEN--LTMYSEVLQDST-FDLIDAGKLRFASGSSITLSPR 316 Query: 376 -GASFFSSDESF---------------AMIRGGHVDLTMLGAMQVSKYGDLANWMIPG-K 418 A F + E + ++R + + + A++ YG++ + + G K Sbjct: 317 RNADVFGNLERYKDKLVLRPQEISNHPEVVRRLGI-IGINTALEFDIYGNVNSTHVGGTK 375 Query: 419 MVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDV 478 M+ G+GG+ D +A + VT + GN ++ + + V+ ++TE+ + D+ Sbjct: 376 MMNGIGGSGDFARNAHLAIFVTKSIAKGGNISSVVPMVSHVDHTEHDVDILVTEQGLADL 435 Query: 479 DK 480 Sbjct: 436 RG 437 >5VVW-A nrPDB Length = 315 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 33/166 (19%), Positives = 58/166 (34%), Gaps = 15/166 (9%) Query: 59 VLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLL------RSKQIKRMV 112 V +GG G+CGI E L++ + L A + ++ FG + + +V Sbjct: 14 VGIGGAGMCGIAEVLLNLGYEVSGSDLKASAVTERLEKFGAQIFIGHQAENADGADVLVV 73 Query: 113 SSYVGENAEFERQYLSGELEVELTPQGTLAERIR----AGGAGVPAFYTPTG-YGTLVQE 167 SS + L + V + LAE +R AG T T ++ Sbjct: 74 SSAINRANPEVASALERRIPVVPRAE-MLAELMRYRHGIAVAGTHGKTTTTSLIASVFAA 132 Query: 168 GGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAW 213 GG + G + A + +++ EA D + + Sbjct: 133 GGLDPTFVIGGRLNAAGT---NAQLGASRYLVAEADESDASFLHLQ 175 >5N1Q-B nrPDB Length = 443 Score = 34.0 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 63/164 (38%), Gaps = 8/164 (4%) Query: 226 SARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIR 285 R +LP+ + AE + EVE+I+ I P+D + + G++ ++ + Sbjct: 70 PGRTLDLPIVENAEAIMDEVEKILRI---TPDD----DTQLRAINDGKQLVVQVPSKRLE 122 Query: 286 KEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGI-GIPLLASNFISPNITVHLQSE 344 + ++E IIK ++ DG + I G +++ NI L + Sbjct: 123 VAAEYSVSMLNTAMALKEAIIKTFDVDLFDGSTIHAAIVGRYPQVMDYMGGNIASLLGAP 182 Query: 345 NGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAM 388 + + GLG R + + K + + AS F M Sbjct: 183 SNMEGLGYALRNIMVNHYVATTKKNLMNAVAFASIMEQTAMFEM 226 >3B0X-A nrPDB Length = 575 Score = 32.4 bits (72), Expect = 0.51, Method: Composition-based stats. Identities = 57/273 (20%), Positives = 102/273 (37%), Gaps = 33/273 (12%) Query: 74 IDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEV 133 I+ + + G + L + G+G L K ++ + + V ++ E R+ G LEV Sbjct: 44 IEEIAEKGKEALMELP--------GVGPDLAEKILEFLRTGKVRKHEELSRKVPRGVLEV 95 Query: 134 ELTPQ-GTLAERIRAGGAGVPAF-----YTPTGYGTLVQE-GGSPIKYNKDG--SVAIAS 184 P G R+ G G+ + G T ++ G + ++G A Sbjct: 96 MEVPGVGPKTARLLYEGLGIDSLEKLKAALDRGDLTRLKGFGPKRAERIREGLALAQAAG 155 Query: 185 KPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMC-----KAAE 239 K R + L EAI + +A A ++ + + + + +A E Sbjct: 156 KRRPLGAVLSLARSLLEAIRALPGVERAELCGSARR--YKDTVGDLDFLVASREGERAVE 213 Query: 240 --TTVVEVEEIVDIGAFAPEDIHIPQIYVH-RLIKGEKYEKRIERL------SIRKEGDG 290 + +V+E+ G + V R++ E Y ++ L SIR Sbjct: 214 GFVRLPQVKEVYAKGKERATVFLKNGLQVDLRVVPPESYGAGLQYLTGSAAHSIRLRALA 273 Query: 291 EAKSAKPGDDVRERIIKRAALEFEDGMYANLGI 323 + K K + R KR A E E+ +YA LG+ Sbjct: 274 QEKGLKLSEYGVFRGEKRIAGETEEEVYAALGL 306 >2DZD-A nrPDB Length = 461 Score = 32.0 bits (71), Expect = 0.71, Method: Composition-based stats. Identities = 36/219 (16%), Positives = 69/219 (31%), Gaps = 37/219 (16%) Query: 113 SSYVGENAEFERQYLSGELEVELTPQGTL-------AERIRAGGAGVPAFYTPTGYGTLV 165 ++ EN +F ++ + + L R A AG+P G Sbjct: 87 YGFLSENIQFAKRCREEGIIFIGPNENHLDMFGDKVKARHAAVNAGIPVIPGSDG----- 141 Query: 166 QEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRK 225 DG + + E +G I++ A+ G ++ ++ F + Sbjct: 142 ---------PVDGLEDVVAF----AEAHGYPIIIKAALGGGGRGMRIVRSKSEVKEAFER 188 Query: 226 SARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIP--QIYVHRLIKGEKYEKRIERLS 283 + A+ E V+ P+ I + Y ++ YE+ Sbjct: 189 AK--------SEAKAAFGSDEVYVEKLIENPKHIEVQILGDYEGNIV--HLYERDCSVQR 238 Query: 284 IRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLG 322 ++ A S D++R+RI + A Y N G Sbjct: 239 RHQKVVEVAPSVSLSDELRQRICEAAVQLMRSVGYVNAG 277 >4OTD-A nrPDB Length = 341 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 48/236 (20%), Positives = 68/236 (28%), Gaps = 61/236 (25%) Query: 22 ATWYKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVLVGGFGLC-------------- 67 A +Y CV H H Y D + V + FGLC Sbjct: 116 AIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFC 175 Query: 68 GIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQI----------KRMVSSYVG 117 G PE L + LT S VD +GLG+LL + + + S V Sbjct: 176 GTPEFLAPEV-------LTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVN 228 Query: 118 ENAEFERQYLSGELEV-----ELTPQGTLAERIRAG------------------GAGVPA 154 + + R + + + P+ L R +P Sbjct: 229 DEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPP 288 Query: 155 FYTPTGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALV 210 + PT G + S G S PR+ R E+A DF V Sbjct: 289 PFVPTLSG---RTDVSNFDEEFTGEAPTLSPPRDARPLT----AAEQAAFLDFDFV 337 >4CRS-A nrPDB Length = 341 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 26/101 (25%), Positives = 34/101 (33%), Gaps = 21/101 (20%) Query: 22 ATWYKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVLVGGFGLC-------------- 67 A +Y CV H H Y D + V + FGLC Sbjct: 116 AVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFC 175 Query: 68 GIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQI 108 G PE L + LT S VD +GLG+L+ + Sbjct: 176 GTPEFLAPEV-------LTETSYTRAVDWWGLGVLIYEMLV 209 >5MDH-A nrPDB Length = 333 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 31/82 (37%), Gaps = 9/82 (10%) Query: 418 KMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFD 477 K+ K G A+D + KV+V + ++P C+ R+ Sbjct: 106 KIFKCQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRL-------- 157 Query: 478 VDKKKGLTLIELWEGLTVDDVQ 499 D + I L G+T DDV+ Sbjct: 158 -DHNRAKAQIALKLGVTSDDVK 178 >1H76-A nrPDB Length = 696 Score = 29.3 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%) Query: 253 AFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDDVRERIIKRAALE 312 +P+ V G + ++ + SI G E SA+ +D +I+K A Sbjct: 333 EISPDSSKNECKKVRWCAIGHEETQKCDAWSINSGGKIECVSAENTEDCIAKIVKGEADA 392 Query: 313 FE-DGMY----ANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLIN-A 366 DG Y G+ +P+LA N+ + E G L + + D + N Sbjct: 393 MSLDGGYIYIAGKCGL-VPVLAENYKTEGENCVNTPEKGYLAVAVVKKSSGPDLNWNNLK 451 Query: 367 GKETV 371 GK++ Sbjct: 452 GKKSC 456 >6DVI-A nrPDB Length = 394 Score = 29.0 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 28/171 (16%), Positives = 46/171 (26%), Gaps = 23/171 (13%) Query: 63 GFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEF 122 G GL G+ L + A+ G +++ + G Sbjct: 13 GQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRM 72 Query: 123 ERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSVAI 182 +L VEL + A P F+ P G L + G + S Sbjct: 73 LMAATERDLSVELWGKTWAA----------PMFFAPIGVIALCAQDGHGDAASAQASART 122 Query: 183 ----------ASKPREVREFNGQHFILEEAITG---DFALVKAWKADRAGN 220 S ++R+ G + D A +A+ AG Sbjct: 123 GVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGY 173 >3RV0-A nrPDB Length = 341 Score = 29.0 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 36/81 (44%) Query: 433 AKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEG 492 AK+ +V E K +++ E + G + R +TE F V+ K G L++ EG Sbjct: 241 AKSSQMVIKEPLNKNAKNELAELLQINKLGHKLHYRKLTEMPPFRVEVKIGDILLDEAEG 300 Query: 493 LTVDDVQKSTGCDFAVSPKLM 513 ++ + + + +L+ Sbjct: 301 NSIREAEHRAAMKVLENDELL 321 >5TWA-A nrPDB Length = 187 Score = 29.0 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 34/122 (27%), Gaps = 1/122 (0%) Query: 115 YVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKY 174 Y E A G E E AER+ A AG P + G Sbjct: 41 YWREPASTVGAASDGLSEEERRTAADAAERMTAVIAGTPGIAVERNVRDFRRGGWDVTPD 100 Query: 175 NKDGSVAIASKPREVREFNGQHFILEEAITGDF-ALVKAWKADRAGNVIFRKSARNFNLP 233 N + + + I A + F A V + D +F + R N Sbjct: 101 NVESEFREVERRTFSDGVHWGRVIAFLAFSMSFAAYVNSRGIDGGAYSVFNWTLRVLNDS 160 Query: 234 MC 235 + Sbjct: 161 LA 162 >1TQY-A nrPDB Length = 424 Score = 28.6 bits (62), Expect = 7.3, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 47/134 (35%) Query: 75 DALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVE 134 +A +G+ T GV S + + ++ S G + E + +LS + Sbjct: 83 EAFAASGLDPDTLDPARVGVSLGSAVAAATSLEREYLLLSDSGRDWEVDAAWLSRHMFDY 142 Query: 135 LTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNG 194 L P AE A GA P TG + + G+ ++ ++GS + Sbjct: 143 LVPSVMPAEVAWAVGAEGPVTMVSTGCTSGLDSVGNAVRAIEEGSADVMFAGAADTPITP 202 Query: 195 QHFILEEAITGDFA 208 +AI A Sbjct: 203 IVVACFDAIRATTA 216 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.126 0.313 Lambda K H 0.267 0.0387 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,610,589 Number of Sequences: 36641 Number of extensions: 681771 Number of successful extensions: 2050 Number of sequences better than 10.0: 38 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 1955 Number of HSP's gapped (non-prelim): 69 length of query: 520 length of database: 10,336,785 effective HSP length: 101 effective length of query: 419 effective length of database: 6,636,044 effective search space: 2780502436 effective search space used: 2780502436 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.2 bits)