BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P55273 (166 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1BD8-A nrPDB 308 7e-85 1BLX-B nrPDB 288 6e-79 1G3N-B nrPDB 121 1e-28 1D9S-A nrPDB 104 2e-23 2A5E-A nrPDB 100 4e-22 5AQB-A nrPDB 88 2e-18 6MWQ-A nrPDB 84 4e-17 5AQA-A nrPDB 82 2e-16 5H76-A nrPDB 82 2e-16 5AQ9-A nrPDB 81 3e-16 5CBO-A nrPDB 75 1e-14 5MIO-C nrPDB 75 1e-14 6FES-A nrPDB 71 2e-13 5AQ7-A nrPDB 69 1e-12 5ET1-A nrPDB 67 4e-12 5GP7-A nrPDB 64 2e-11 4Z68-A nrPDB 63 6e-11 3EU9-A nrPDB 62 1e-10 3B7B-A nrPDB 56 8e-09 6BY9-A nrPDB 55 2e-08 6AUN-A nrPDB 55 2e-08 5JHQ-A nrPDB 55 2e-08 3T9K-A nrPDB 49 8e-07 5D68-A nrPDB 49 1e-06 2KXP-C nrPDB 49 1e-06 4NIK-A nrPDB 49 1e-06 2DWZ-A nrPDB 49 1e-06 5HKP-A nrPDB 46 7e-06 4O1O-A nrPDB 46 9e-06 5DND-A nrPDB 45 1e-05 4OAU-C nrPDB 44 2e-05 3ZKJ-A nrPDB 44 4e-05 6EMK-G nrPDB 44 5e-05 1WG0-A nrPDB 44 5e-05 4OT9-A nrPDB 42 1e-04 5UQE-A nrPDB 42 2e-04 3LJN-A nrPDB 42 2e-04 5U0J-A nrPDB 42 2e-04 6E2G-A nrPDB 38 0.002 5U0K-A nrPDB 37 0.005 5IRX-A nrPDB 36 0.010 2RFA-A nrPDB 35 0.012 6DMR-A nrPDB 34 0.023 2NYJ-A nrPDB 34 0.026 3DEO-A nrPDB 34 0.034 3UI2-A nrPDB 34 0.035 6CV9-A nrPDB 31 0.22 2ETB-A nrPDB 31 0.24 6BOA-A nrPDB 30 0.33 6BO5-A nrPDB 30 0.65 5HI9-A nrPDB 30 0.65 3W9G-A nrPDB 29 1.2 5UIL-A nrPDB 28 1.4 6CUD-A nrPDB 28 1.5 5V8F-9 nrPDB 28 2.3 2F37-A nrPDB 28 2.5 5IMY-A nrPDB 28 2.8 6DQP-A nrPDB 27 3.2 4Q1T-A nrPDB 27 3.4 3ERJ-A nrPDB 27 3.4 6MHW-A nrPDB 27 3.5 6DJS-A nrPDB 27 3.6 6OGN-A nrPDB 27 4.1 5C70-A nrPDB 26 8.7 >1BD8-A nrPDB Length = 156 Score = 308 bits (789), Expect = 7e-85, Method: Compositional matrix adjust. Identities = 156/156 (100%), Positives = 156/156 (100%) Query: 7 RAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGAS 66 RAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGAS Sbjct: 1 RAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGAS 60 Query: 67 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL Sbjct: 61 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 120 Query: 127 AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHM 162 AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHM Sbjct: 121 AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHM 156 >1BLX-B nrPDB Length = 166 Score = 288 bits (738), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 144/166 (86%), Positives = 154/166 (92%) Query: 1 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL 60 MLLEEV GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGS A+ALEL Sbjct: 1 MLLEEVCVGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALEL 60 Query: 61 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT 120 LKQGASPNVQD SGTSPVHDAARTGFLDTLKVLVEHGADVN D TG+LPIHLA++EGH+ Sbjct: 61 LKQGASPNVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHS 120 Query: 121 AVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL 166 +VVSFLA ESDLH RDA GLTPLELA QRGAQ+L+DILQGHM+ P+ Sbjct: 121 SVVSFLAPESDLHHRDASGLTPLELARQRGAQNLMDILQGHMMIPM 166 >1G3N-B nrPDB Length = 168 Score = 121 bits (303), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 68/155 (43%), Positives = 100/155 (64%), Gaps = 3/155 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPN 68 G+ L+ AAARGD++++ LL + FG+TALQVM G+ IA LL +GA+P+ Sbjct: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNG-FGRTALQVMKLGNPEIARRLLLRGANPD 64 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 128 ++D +G + +HDAAR GFLDTL+ L+E ADVN+ D G LP+HLA +EGH VV FL Sbjct: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 Query: 129 E--SDLHRRDARGLTPLELALQRGAQDLVDILQGH 161 S++ R+ +G T +LA G ++V ++Q + Sbjct: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 >1D9S-A nrPDB Length = 136 Score = 104 bits (259), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 61/120 (50%), Positives = 77/120 (64%), Gaps = 2/120 (1%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQD 71 L+ AAARG V+ VR+LL P+ALNRFG+ +QVMM GS +A LL GA PN D Sbjct: 16 LATAAARGQVETVRQLLEAG-ADPNALNRFGRRPIQVMMMGSAQVAELLLLHGAEPNCAD 74 Query: 72 TSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAES 130 + T PVHDAAR GFLDTL VL GA ++V D G LP+ LA ++GH + +L A + Sbjct: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIARYLHAAT 134 >2A5E-A nrPDB Length = 156 Score = 99.8 bits (247), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 61/122 (50%), Positives = 76/122 (62%), Gaps = 2/122 (1%) Query: 8 AGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASP 67 + D L+ AAARG V+EVR LL + P+A N +G+ +QVMM GS +A LL GA P Sbjct: 12 SADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARVAELLLLHGAEP 70 Query: 68 NVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 N D + T PVHDAAR GFLDTL VL GA ++V D G LP+ LA + GH V +L Sbjct: 71 NCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 Query: 127 AA 128 A Sbjct: 131 RA 132 >5AQB-A nrPDB Length = 428 Score = 87.8 bits (216), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 53/144 (36%), Positives = 80/144 (55%), Gaps = 1/144 (0%) Query: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGT 75 AAR + R+L +AL+ G T L + +G I LLK GA N D G Sbjct: 21 AARAGQDDECRILMANGADVNALDEVGWTPLHLAAWGHLEIVECLLKNGADVNAADIDGY 80 Query: 76 SPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLHR 134 +P+H AA +G L+ ++VL+++GADVN D G P+HLA GH +V L +D++ Sbjct: 81 TPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVNA 140 Query: 135 RDARGLTPLELALQRGAQDLVDIL 158 +D G TP +LA+ G +D+ ++L Sbjct: 141 QDKFGKTPRDLAIDNGNEDIAEVL 164 Score = 55.1 bits (131), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 2/118 (1%) Query: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASPNVQDTSG 74 AA G ++ V LL + +A + G T L + F G I LLK GA N D +G Sbjct: 54 AAWGHLEIVECLL-KNGADVNAADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAG 112 Query: 75 TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDL 132 +P+H AA G L+ ++VL+++GADVN D G P LA+ G+ + L + L Sbjct: 113 FTPLHLAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATL 170 Score = 30.4 bits (67), Expect = 0.40, Method: Compositional matrix adjust. Identities = 21/55 (38%), Positives = 25/55 (45%) Query: 50 MFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPD 104 +FG I LLK GA N QD G +P A G D +VL + V V D Sbjct: 121 IFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKD 175 >6MWQ-A nrPDB Length = 493 Score = 83.6 bits (205), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 58/153 (37%), Positives = 84/153 (54%), Gaps = 3/153 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVM-MFGSTAIALELLKQGASP 67 G +L AA G EVR L+ +AL+RFG T L + G I LLK GA Sbjct: 6 GKKLLEAARAGQDDEVRILMANG-ADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADV 64 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 N D G +P+H AA G L+ ++VL+++GADVN D G P+HL +GH +V L Sbjct: 65 NAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLL 124 Query: 128 AE-SDLHRRDARGLTPLELALQRGAQDLVDILQ 159 +D++ +D G T ++++ G +DL +ILQ Sbjct: 125 KHGADVNAQDKFGKTAFDISIDNGNEDLAEILQ 157 >5AQA-A nrPDB Length = 418 Score = 81.6 bits (200), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 41/100 (41%), Positives = 65/100 (65%), Gaps = 1/100 (1%) Query: 60 LLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGH 119 L+ GA N D +GT+P+H AA +G L+ ++VL++HGADV+ D G P+HLA GH Sbjct: 33 LMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGH 92 Query: 120 TAVVSFLAAE-SDLHRRDARGLTPLELALQRGAQDLVDIL 158 +V L +D++ D+ G+TPL LA + G +++V++L Sbjct: 93 LEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVL 132 Score = 64.7 bits (156), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 38/107 (35%), Positives = 59/107 (55%), Gaps = 1/107 (0%) Query: 23 EVRRLLHRELVHPDALNRFGKTALQVM-MFGSTAIALELLKQGASPNVQDTSGTSPVHDA 81 E+ +L + DA + FG T L + +G I LLK GA N D+ G +P+H A Sbjct: 61 EIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLA 120 Query: 82 ARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 128 A+ G+ + ++VL++ GADV+ D G P+ LA +GH + + L A Sbjct: 121 AKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVA 167 >5H76-A nrPDB Length = 201 Score = 81.6 bits (200), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 42/103 (40%), Positives = 65/103 (63%), Gaps = 1/103 (0%) Query: 60 LLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGH 119 L+ GA N D +GT+P+H AA +G L+ ++VL++HGADV+ D G P+HLA GH Sbjct: 25 LMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGH 84 Query: 120 TAVVSFLAAE-SDLHRRDARGLTPLELALQRGAQDLVDILQGH 161 +V L +D++ D+ G+TPL LA + G ++V++L H Sbjct: 85 LEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKH 127 Score = 77.4 bits (189), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 52/151 (34%), Positives = 79/151 (52%), Gaps = 2/151 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASP 67 G +L AA G EVR L+ +A + G T L + + G I LLK GA Sbjct: 7 GRKLLEAARAGQDDEVRILMANG-ADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV 65 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 + D G +P+H AA G L+ ++VL+++GADVN D G P+HLA + G+ +V L Sbjct: 66 DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLL 125 Query: 128 AESDLHRRDARGLTPLELALQRGAQDLVDIL 158 ++ +D G T ++++ G +DL IL Sbjct: 126 KHGAVNAQDKFGKTAFDISIDNGNEDLAQIL 156 >5AQ9-A nrPDB Length = 422 Score = 80.9 bits (198), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 42/103 (40%), Positives = 65/103 (63%), Gaps = 1/103 (0%) Query: 60 LLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGH 119 L+ GA N D +GT+P+H AA +G L+ ++VL++HGADV+ D G P+HLA GH Sbjct: 33 LMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGH 92 Query: 120 TAVVSFLAAE-SDLHRRDARGLTPLELALQRGAQDLVDILQGH 161 +V L +D++ D+ G+TPL LA + G ++V++L H Sbjct: 93 LEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKH 135 Score = 76.3 bits (186), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 55/153 (35%), Positives = 81/153 (52%), Gaps = 3/153 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASP 67 G +L AA G EVR L+ +A + G T L + + G I LLK GA Sbjct: 15 GRKLLEAARAGQDDEVRILMANG-ADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV 73 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 + D G +P+H AA G L+ ++VL+++GADVN D G P+HLA + G+ +V L Sbjct: 74 DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLL 133 Query: 128 AE-SDLHRRDARGLTPLELALQRGAQDLVDILQ 159 +D++ +D G TP +LA G D+ +LQ Sbjct: 134 KHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQ 166 Score = 67.4 bits (163), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 46/129 (35%), Positives = 68/129 (52%), Gaps = 2/129 (1%) Query: 23 EVRRLLHRELVHPDALNRFGKTALQVM-MFGSTAIALELLKQGASPNVQDTSGTSPVHDA 81 E+ +L + DA + FG T L + +G I LLK GA N D+ G +P+H A Sbjct: 61 EIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLA 120 Query: 82 ARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLT 141 A+ G+L+ ++VL++HGADVN D G P LA G+ V + L + + AR + Sbjct: 121 AKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAAADQLGAR-VG 179 Query: 142 PLELALQRG 150 +EL L G Sbjct: 180 YIELDLNSG 188 >5CBO-A nrPDB Length = 176 Score = 75.5 bits (184), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 37/100 (37%), Positives = 60/100 (60%), Gaps = 1/100 (1%) Query: 60 LLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGH 119 L+ GA N D G +P+H AA G + ++VL+++GADVN D TG P+HLA + G+ Sbjct: 22 LMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASDATGDTPLHLAAKWGY 81 Query: 120 TAVVS-FLAAESDLHRRDARGLTPLELALQRGAQDLVDIL 158 +V L +D++ +D G T ++++ G +DL +IL Sbjct: 82 LGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEIL 121 >5MIO-C nrPDB Length = 573 Score = 75.5 bits (184), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 55/153 (35%), Positives = 83/153 (54%), Gaps = 3/153 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVM-MFGSTAIALELLKQGASP 67 G +L AA G EVR L+ +A + G T L + +G I LLK GA Sbjct: 411 GKKLLEAARAGQDDEVRVLMANG-ADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADV 469 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVV-SFL 126 + D G++P+H AA G L+ ++VL++HGADVN D G P+ LA GH +V + L Sbjct: 470 SASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALL 529 Query: 127 AAESDLHRRDARGLTPLELALQRGAQDLVDILQ 159 +D++ +D G T + ++ G++DL +ILQ Sbjct: 530 KHGADVNAQDKFGKTAYDTSIDNGSEDLAEILQ 562 Score = 69.7 bits (169), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 46/122 (37%), Positives = 64/122 (52%), Gaps = 1/122 (0%) Query: 41 FGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADV 100 GK L+ G L+ GA N D SG +P+H AA G L+ ++VL++HGADV Sbjct: 410 LGKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADV 469 Query: 101 NVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLHRRDARGLTPLELALQRGAQDLVDILQ 159 + D G+ P+HLA GH +V L +D++ D G TPL LA G +V+ L Sbjct: 470 SASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALL 529 Query: 160 GH 161 H Sbjct: 530 KH 531 >6FES-A nrPDB Length = 367 Score = 70.9 bits (172), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 54/146 (36%), Positives = 73/146 (50%), Gaps = 3/146 (2%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASP 67 G +L AA G EVR LL + + G T L + + G I LLK GA Sbjct: 7 GKKLLEAARAGQDDEVRILLANG-ADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV 65 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 N D G +P+H AA TG L+ ++VL+++GA VN D G P+HLA GH +V L Sbjct: 66 NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLL 125 Query: 128 AE-SDLHRRDARGLTPLELALQRGAQ 152 +D +D G TP +LA G + Sbjct: 126 KNGADARAQDKFGKTPEDLARDNGYE 151 >5AQ7-A nrPDB Length = 418 Score = 68.6 bits (166), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 43/119 (36%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Query: 41 FGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADV 100 GK L+ G LL GA N D +G +P+H AA G L ++VL+++GADV Sbjct: 14 LGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV 73 Query: 101 NVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLHRRDARGLTPLELALQRGAQDLVDIL 158 N D G P+HLA GH +V L + ++ D G PL LA G +++V++L Sbjct: 74 NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVL 132 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 35/94 (37%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Query: 36 DALNRFGKTALQVMMF-GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLV 94 +A + G T L + + G I LLK GA N D GT+P+H AA G+ + ++VL+ Sbjct: 74 NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLL 133 Query: 95 EHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 128 + GADV+ D G P+ LA +GH + + L A Sbjct: 134 KAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVA 167 >5ET1-A nrPDB Length = 353 Score = 67.0 bits (162), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 52/141 (36%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQG-ASPNVQDT 72 AAA G + ++ LL + + G T L + FG + LL QG A+ + Sbjct: 78 AAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTD 137 Query: 73 SGTSPVHDAARTGFLDTLKVLVEHGAD-VNVPDGTGALPIHLAVQEGHTAVVSFLAAE-- 129 +G P+H AA G L +LK+LV H + VN GA P++LA QEGH V +L E Sbjct: 138 TGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECS 197 Query: 130 SDLHRRDARGLTPLELALQRG 150 +D H R G+TPL A Q G Sbjct: 198 ADPHLRAQDGMTPLHAAAQMG 218 Score = 50.4 bits (119), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 45/151 (29%), Positives = 68/151 (45%), Gaps = 11/151 (7%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQ-----GASPNV 69 AAA+GD+ ++ L+ +P+ +N + LE+ K A P++ Sbjct: 146 AAAKGDLPSLKLLVGH---YPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHL 202 Query: 70 QDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVP--DGTGALPIHLAVQEGHTAVVSFLA 127 + G +P+H AA+ G L LV ADV+ D GA +H A GHT V+S+L Sbjct: 203 RAQDGMTPLHAAAQMGHNPVLVWLVSF-ADVSFSEQDHDGATAMHFAASRGHTKVLSWLL 261 Query: 128 AESDLHRRDARGLTPLELALQRGAQDLVDIL 158 +D G TPL A + G + IL Sbjct: 262 LHGAEISQDLWGGTPLHDAAENGELECCQIL 292 Score = 44.3 bits (103), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 3/95 (3%) Query: 67 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDG-TGALPIHLAVQEGHTAVVSF 125 P+++D+ PVH AAR+G L L+ LVE A V GA P H A G+ + + + Sbjct: 30 PSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVSRARNGATPAHDAAATGYLSCLQW 89 Query: 126 LAAE--SDLHRRDARGLTPLELALQRGAQDLVDIL 158 L + + +D G T L LA + G D+V L Sbjct: 90 LLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWL 124 Score = 43.9 bits (102), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Query: 52 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPI 111 G T + LL GA + QD G +P+HDAA G L+ ++L +GA ++V D G Sbjct: 252 GHTKVLSWLLLHGAEIS-QDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAA 310 Query: 112 HLAVQEGHTAVVSFL 126 LA GHT +L Sbjct: 311 DLAEFNGHTHCSRYL 325 >5GP7-A nrPDB Length = 169 Score = 64.3 bits (155), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 42/134 (31%), Positives = 68/134 (50%), Gaps = 2/134 (1%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTS 73 AA +G + V++L E ++ T L + + + +A LL+ GA N QD Sbjct: 16 AAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKG 75 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDL 132 G P+H+AA G +D +L+++ VN D P+H A Q+G T + + L A +D Sbjct: 76 GLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 135 Query: 133 HRRDARGLTPLELA 146 ++ G TPL+LA Sbjct: 136 TMKNQEGQTPLDLA 149 Score = 60.5 bits (145), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 3/101 (2%) Query: 68 NVQDTSG--TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSF 125 N +DT G ++P+H AA L+ + L+EHGADVN D G +P+H A GH + + Sbjct: 35 NCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAAL 94 Query: 126 L-AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAP 165 L + ++ D TPL A Q+G L +L H P Sbjct: 95 LIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 135 Score = 40.0 bits (92), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 33/67 (49%) Query: 51 FGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALP 110 +G IA L+K N D +P+H+AA+ G +L+ HGAD + + G P Sbjct: 86 YGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTP 145 Query: 111 IHLAVQE 117 + LA + Sbjct: 146 LDLATAD 152 >4Z68-A nrPDB Length = 155 Score = 63.2 bits (152), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 44/147 (29%), Positives = 75/147 (51%), Gaps = 3/147 (2%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTS 73 AA GDV+ V++L + V+ + T L + ++ LL+ GA + +D Sbjct: 10 AAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG 69 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDL 132 G P+H+A G + ++LV+HGA VNV D P+H A +G + L +D Sbjct: 70 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 129 Query: 133 HRRDARGLTPLELALQRGAQDLVDILQ 159 +++ G TPL+L ++ G D+ D+L+ Sbjct: 130 TKKNRDGNTPLDL-VKDGDTDIQDLLR 155 Score = 38.5 bits (88), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 4/85 (4%) Query: 80 DAARTGFLDTLKVLVEHGADVNVPD--GTGALPIHLAVQEGHTAVVSFLAAE-SDLHRRD 136 +AA+ G ++T+K L + VN D G + P+H A +VV +L +D+H +D Sbjct: 9 EAAKAGDVETVKKLCTVQS-VNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKD 67 Query: 137 ARGLTPLELALQRGAQDLVDILQGH 161 GL PL A G ++ ++L H Sbjct: 68 KGGLVPLHNACSYGHYEVAELLVKH 92 >3EU9-A nrPDB Length = 240 Score = 62.0 bits (149), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 32/77 (41%), Positives = 48/77 (62%), Gaps = 1/77 (1%) Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDL 132 ++P+H A R G L + L+++GAD ++ DG G IHLA Q GHT++V++L A+ D+ Sbjct: 76 NSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 135 Query: 133 HRRDARGLTPLELALQR 149 D G+TPL A R Sbjct: 136 DMMDQNGMTPLMWAAYR 152 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 37/144 (25%), Positives = 64/144 (44%), Gaps = 36/144 (25%) Query: 52 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALP- 110 G ++ ++L+K GA P++ D G S +H AA+ G + L+ G DV++ D G P Sbjct: 87 GHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPL 146 Query: 111 ----------------------------------IHLAVQEGHTAVVS-FLAAESDLHRR 135 +H AV G+T V+S L A +++ + Sbjct: 147 MWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQ 206 Query: 136 DARGLTPLELALQRGAQDLVDILQ 159 + +G + L+LA QR +++ LQ Sbjct: 207 NIKGESALDLAKQRKNVWMINHLQ 230 Score = 29.6 bits (65), Expect = 0.57, Method: Compositional matrix adjust. Identities = 30/123 (24%), Positives = 44/123 (35%), Gaps = 35/123 (28%) Query: 71 DTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPD-----------------------GTG 107 D T + A + G + + LVE G DV PD G Sbjct: 6 DDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKG 65 Query: 108 AL-----------PIHLAVQEGH-TAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLV 155 A+ P+H A ++GH + VV + +D D G + + LA Q G +V Sbjct: 66 AIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIV 125 Query: 156 DIL 158 L Sbjct: 126 AYL 128 >3B7B-A nrPDB Length = 237 Score = 55.8 bits (133), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 2/109 (1%) Query: 52 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPI 111 G I L++ GA+ + +P+ +AA L+ +K L++ GA V+ D G+ + Sbjct: 22 GHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCL 81 Query: 112 HLAVQEGHTAVVSFLAA--ESDLHRRDARGLTPLELALQRGAQDLVDIL 158 HLA ++GH VV +L + + D++ +D G TP+ A + DLV +L Sbjct: 82 HLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLL 130 Score = 52.0 bits (123), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 37/137 (27%), Positives = 72/137 (52%), Gaps = 8/137 (5%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLK----QGASPNVQ 70 AA +G + V+ LL + + + G T M++ + ++L+K +G+ N++ Sbjct: 84 AAKKGHYEVVQYLLSNGQMDVNCQDDGGWTP---MIWATEYKHVDLVKLLLSKGSDINIR 140 Query: 71 DTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEG-HTAVVSFLAAE 129 D +H AA +G +D ++L+ D++ + G P+H+A +E + VV FL+ + Sbjct: 141 DNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRD 200 Query: 130 SDLHRRDARGLTPLELA 146 SD+ ++ G TPL+ A Sbjct: 201 SDVTLKNKEGETPLQCA 217 Score = 52.0 bits (123), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FL 126 N QD G +P+ A +D +K+L+ G+D+N+ D + +H A G + L Sbjct: 105 NCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILL 164 Query: 127 AAESDLHRRDARGLTPLELALQRGAQDLV 155 AA+ DLH + G +PL +A + D V Sbjct: 165 AAKCDLHAVNIHGDSPLHIAARENRYDCV 193 Score = 43.5 bits (101), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 1/84 (1%) Query: 76 SPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL-AAESDLHR 134 SP+H AA G +D +LV+ GA+++ P+ A + H V +L A + + Sbjct: 13 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 72 Query: 135 RDARGLTPLELALQRGAQDLVDIL 158 +DA G T L LA ++G ++V L Sbjct: 73 KDAEGSTCLHLAAKKGHYEVVQYL 96 >6BY9-A nrPDB Length = 328 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 2/109 (1%) Query: 52 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPI 111 G I L++ GA+ + +P+ +AA L+ +K L++ GA V+ D G+ + Sbjct: 113 GHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCL 172 Query: 112 HLAVQEGHTAVVSFLAA--ESDLHRRDARGLTPLELALQRGAQDLVDIL 158 HLA ++GH VV +L + + D++ +D G TP+ A + DLV +L Sbjct: 173 HLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLL 221 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 36/134 (26%), Positives = 68/134 (50%), Gaps = 2/134 (1%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTAL-QVMMFGSTAIALELLKQGASPNVQDTS 73 AA +G + V+ LL + + + G T + + + LL +G+ N++D Sbjct: 175 AAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNE 234 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEG-HTAVVSFLAAESDL 132 +H AA +G +D ++L+ D++ + G P+H+A +E + VV FL+ +SD+ Sbjct: 235 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDV 294 Query: 133 HRRDARGLTPLELA 146 ++ G TPL+ A Sbjct: 295 TLKNKEGETPLQCA 308 Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FL 126 N QD G +P+ A +D +K+L+ G+D+N+ D + +H A G + L Sbjct: 196 NCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILL 255 Query: 127 AAESDLHRRDARGLTPLELALQRGAQDLV 155 AA+ DLH + G +PL +A + D V Sbjct: 256 AAKCDLHAVNIHGDSPLHIAARENRYDCV 284 Score = 45.4 bits (106), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 32/104 (30%), Positives = 53/104 (50%), Gaps = 3/104 (2%) Query: 58 LELLKQGASPN--VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAV 115 L +L G PN ++ + SP+H AA G +D +LV+ GA+++ P+ A Sbjct: 84 LLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAA 143 Query: 116 QEGHTAVVSFL-AAESDLHRRDARGLTPLELALQRGAQDLVDIL 158 + H V +L A + + +DA G T L LA ++G ++V L Sbjct: 144 ENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYL 187 >6AUN-A nrPDB Length = 752 Score = 54.7 bits (130), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 33/94 (35%), Positives = 54/94 (57%), Gaps = 3/94 (3%) Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHG-ADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 + ++ G +P+H A R G + L LV++ A ++V D G H AVQ ++ V+ L Sbjct: 146 STENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLL 205 Query: 127 A--AESDLHRRDARGLTPLELALQRGAQDLVDIL 158 A + L++ + +GLTPL LA Q G Q++V +L Sbjct: 206 GKNASAGLNQVNKQGLTPLHLACQMGKQEMVRVL 239 Score = 47.8 bits (112), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 6/137 (4%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASP--NVQDT 72 A +GD + + L+ D + G+TA + G + L+LL + AS N + Sbjct: 159 ACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGLNQVNK 218 Query: 73 SGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA--ES 130 G +P+H A + G + ++VL+ A NV G PIH A++ + + S Sbjct: 219 QGLTPLHLACQMGKQEMVRVLLLCNARCNVM-GPSGFPIHTAMKFSQKGCAEMIISMDSS 277 Query: 131 DLHRRDAR-GLTPLELA 146 +H +D R G +PL A Sbjct: 278 QIHSKDPRYGASPLHWA 294 Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 5/121 (4%) Query: 40 RFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD 99 R+G + L + +A LLK+G + +G + +H A D + VL+ +GA+ Sbjct: 285 RYGASPLHWA--KNAEMARMLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGAN 342 Query: 100 VNVPDGTGALPIHLAVQEGHTAVV-SFLAAESDLHRRDARGLTPLELA--LQRGAQDLVD 156 P G P+HLA+ + + ++ + + +++ + G TP +A + + QDL+ Sbjct: 343 AGTPGEHGNTPLHLAISKDNMEMIKALIVFGAEVDTPNDFGETPAFMASKISKQLQDLMP 402 Query: 157 I 157 I Sbjct: 403 I 403 >5JHQ-A nrPDB Length = 482 Score = 54.7 bits (130), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 44/133 (33%), Positives = 56/133 (42%), Gaps = 22/133 (16%) Query: 51 FGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNV--PDGTGA 108 FG + LL QGA PN +D +P+H+AA G +D VL++HGAD N+ DG A Sbjct: 92 FGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSA 151 Query: 109 L----PIHLAVQEGHTAVVSFLAA----------------ESDLHRRDARGLTPLELALQ 148 L P AV G L A + H D R TPL LA Sbjct: 152 LDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAG 211 Query: 149 RGAQDLVDILQGH 161 +V +L H Sbjct: 212 YNRVRIVQLLLQH 224 Score = 52.0 bits (123), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 23/162 (14%) Query: 23 EVRRLLHRELVHPDALNRFGKTAL-QVMMFGSTAIALELLKQGASPNVQDTSGTSPVH-- 79 EV LL + P+A + + T L + + G + + LL+ GA PN+++T G S + Sbjct: 96 EVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 155 Query: 80 ------------------DAARTGFLDTLKVLVEH-GADVNVPDGTGALPIHLAVQEGHT 120 +AAR+G + L L+ + + DG + P+HLA Sbjct: 156 DPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 215 Query: 121 AVVSFLAAE-SDLHRRDARGLTPLELALQRGAQDLVDILQGH 161 +V L +D+H +D GL PL A G ++ ++L H Sbjct: 216 RIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKH 257 Score = 50.4 bits (119), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 39/134 (29%), Positives = 63/134 (47%), Gaps = 2/134 (1%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTS 73 A GDV V+RL+ V+ + + L FG + LL+ GA+ + +D Sbjct: 22 ACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDG 81 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAV-VSFLAAESDL 132 G P+H+A G + + +L+ GAD N D P+H A +G V + L +D Sbjct: 82 GLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP 141 Query: 133 HRRDARGLTPLELA 146 + R+ G + L+LA Sbjct: 142 NIRNTDGKSALDLA 155 Score = 45.4 bits (106), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 1/118 (0%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPN 68 D L AA G+ +++ LL V+ A + T L + + I LL+ GA + Sbjct: 170 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 229 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 +D G P+H+A G + ++L++HGA VN D P+H A + V S L Sbjct: 230 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 287 Score = 43.5 bits (101), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 3/121 (2%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVH---PDALNRFGKTALQVMMFGSTAIALELLKQGA 65 G L AA D+ +V++ L E+++ P + A+ + + LL++GA Sbjct: 323 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGA 382 Query: 66 SPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSF 125 + N ++ +P+H AA D ++VL +HGA +N D G +H A GH Sbjct: 383 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRL 442 Query: 126 L 126 L Sbjct: 443 L 443 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 5/116 (4%) Query: 22 QEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELL-KQGASPNVQDTSGTSPVHD 80 ++V LL R+ + + N+ T L V + +E+L K GA N DT G + +H Sbjct: 371 KQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHR 430 Query: 81 AARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRD 136 AA G L T ++L+ +G+D ++ G A Q G+ AV L+ + + D Sbjct: 431 AALAGHLQTCRLLLSYGSDPSIISLQG----FTAAQMGNEAVQQILSESTPIRTSD 482 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 80 DAARTGFLDTLKVLVEHGADVNVPD--GTGALPIHLAVQEGHTAVVS-FLAAESDLHRRD 136 +A R G + +K LV+ A+VN D G + P+H A G VV L +++H RD Sbjct: 21 EACRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARD 79 Query: 137 ARGLTPLELALQRGAQDLVDIL 158 GL PL A G ++V +L Sbjct: 80 DGGLIPLHNACSFGHAEVVSLL 101 Score = 37.0 bits (84), Expect = 0.004, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 32/64 (50%) Query: 51 FGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALP 110 +G + LLK GA N D +P+H+AA ++ +L+ HGAD + + G Sbjct: 245 YGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSA 304 Query: 111 IHLA 114 + +A Sbjct: 305 VDMA 308 >3T9K-A nrPDB Length = 390 Score = 49.3 bits (116), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 40/134 (29%), Positives = 63/134 (47%), Gaps = 15/134 (11%) Query: 27 LLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGF 86 LL R HP +L T + G+ + + A+P +Q T+ S Sbjct: 202 LLFRASGHPPSL----PTMADALAHGADVNWVNGGQDNATPLIQATAANS---------- 247 Query: 87 LDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FLAAESDLHRRDARGLTPLEL 145 L + L+++GA+VN D G P+H A GHT + FL +DL RD+ G PL + Sbjct: 248 LLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTI 307 Query: 146 ALQRGAQDLVDILQ 159 A++ D+V +L+ Sbjct: 308 AMETANADIVTLLR 321 >5D68-A nrPDB Length = 486 Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 3/98 (3%) Query: 52 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHG-ADVNVPDGTGALP 110 G + + LL + S N D+ +P+H A G ++ ++L+E G + N+ +G + P Sbjct: 49 GDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSP 108 Query: 111 IHLAVQEGHTAVVSFLA--AESDLHRRDARGLTPLELA 146 +H A GH +V L E+D H D +G +PL + Sbjct: 109 LHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNIC 146 Score = 30.8 bits (68), Expect = 0.33, Method: Compositional matrix adjust. Identities = 26/109 (23%), Positives = 50/109 (45%), Gaps = 10/109 (9%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTAL----QVMMFGSTAIALELLKQG-AS 66 L +A GD + + RLL ++N+ +G LL++G + Sbjct: 42 LHRSACEGDSELLSRLLSERF----SVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 97 Query: 67 PNVQDTSGTSPVHDAARTGFLDTLKVLVEH-GADVNVPDGTGALPIHLA 114 PN+ + +SP+H AA G + +++L+ H D ++ D G P+++ Sbjct: 98 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNIC 146 Score = 28.5 bits (62), Expect = 1.5, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 33/87 (37%), Gaps = 2/87 (2%) Query: 77 PVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRD 136 P+H +A G + L L+ VN D PIH A G L + + Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100 Query: 137 ARGL--TPLELALQRGAQDLVDILQGH 161 G +PL A G ++V IL H Sbjct: 101 LNGQLSSPLHFAAGGGHAEIVQILLNH 127 >2KXP-C nrPDB Length = 118 Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 1/83 (1%) Query: 63 QGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAV 122 +G N G P+H AA G L+ L+ L+ GAD+N PD P+ AV EGH + Sbjct: 24 KGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSC 83 Query: 123 VSFLAAE-SDLHRRDARGLTPLE 144 V L ++ +D + GLT LE Sbjct: 84 VKLLLSKGADKTVKGPDGLTALE 106 Score = 37.0 bits (84), Expect = 0.004, Method: Compositional matrix adjust. Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 1/79 (1%) Query: 81 AARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLHRRDARG 139 A + G LD +K V G DVN G P+H A G ++ FL + +D++ D Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHH 68 Query: 140 LTPLELALQRGAQDLVDIL 158 +TPL A+ G V +L Sbjct: 69 ITPLLSAVYEGHVSCVKLL 87 Score = 33.1 bits (74), Expect = 0.063, Method: Compositional matrix adjust. Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 10/101 (9%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLK----QGASPNVQ 70 A GD+ EV+ + + + +NR + + + + + LE+L+ +GA N Sbjct: 9 ALKNGDLDEVKDYVAK----GEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAP 64 Query: 71 DTSGTSPVHDAARTGFLDTLKVLVEHGADVNV--PDGTGAL 109 D +P+ A G + +K+L+ GAD V PDG AL Sbjct: 65 DKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAL 105 >4NIK-A nrPDB Length = 230 Score = 48.5 bits (114), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 1/108 (0%) Query: 52 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPI 111 G T I LL+ G N +D +G SP+H AA G + +K L+ GA VN + G P+ Sbjct: 55 GHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPL 114 Query: 112 HLAVQEG-HTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDIL 158 H A + H V L ++ +D T + A +G ++ IL Sbjct: 115 HYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 162 Score = 43.9 bits (102), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Query: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTAL-QVMMFGSTAIALELLKQGASPNVQDTSG 74 AA + E+ +L +PDA + + TA+ + G+ + LL AS N+QDT G Sbjct: 117 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 176 Query: 75 TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLA 114 +P+H A ++ K+LV GA + + + P+ +A Sbjct: 177 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 216 >2DWZ-A nrPDB Length = 231 Score = 48.5 bits (114), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 1/108 (0%) Query: 52 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPI 111 G T I LL+ G N +D +G SP+H AA G + +K L+ GA VN + G P+ Sbjct: 51 GHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPL 110 Query: 112 HLAVQEG-HTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDIL 158 H A + H V L ++ +D T + A +G +V IL Sbjct: 111 HYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHIL 158 Score = 43.1 bits (100), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 1/100 (1%) Query: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTAL-QVMMFGSTAIALELLKQGASPNVQDTSG 74 AA + E+ +L +PDA + + TA+ + G+ + LL AS N+QDT G Sbjct: 113 AASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEG 172 Query: 75 TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLA 114 +P+H A ++ K LV GA + + + P+ +A Sbjct: 173 NTPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVA 212 >5HKP-A nrPDB Length = 351 Score = 46.2 bits (108), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 3/121 (2%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVH---PDALNRFGKTALQVMMFGSTAIALELLKQGA 65 G L AA D+ +V++ L E+++ P + A+ + +A LL++GA Sbjct: 179 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGA 238 Query: 66 SPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSF 125 + N ++ +P+H AA D ++VL +HGA +N D G +H A GH Sbjct: 239 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRL 298 Query: 126 L 126 L Sbjct: 299 L 299 Score = 45.4 bits (106), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 1/118 (0%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPN 68 D L AA G+ +++ LL V+ A + T L + + I LL+ GA + Sbjct: 26 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 85 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 +D G P+H+A G + ++L++HGA VN D P+H A + V S L Sbjct: 86 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 143 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Query: 80 DAARTGFLDTLKVLVEH-GADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLHRRDA 137 +AAR+G + L L+ + + DG + P+HLA +V L +D+H +D Sbjct: 30 EAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDK 89 Query: 138 RGLTPLELALQRGAQDLVDILQGH 161 GL PL A G ++ ++L H Sbjct: 90 GGLVPLHNACSYGHYEVTELLLKH 113 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 32/64 (50%) Query: 51 FGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALP 110 +G + LLK GA N D +P+H+AA ++ +L+ HGAD + + G Sbjct: 101 YGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSA 160 Query: 111 IHLA 114 + +A Sbjct: 161 VDMA 164 Score = 36.6 bits (83), Expect = 0.005, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 5/116 (4%) Query: 22 QEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELL-KQGASPNVQDTSGTSPVHD 80 ++V LL R+ + + N+ T L V + +E+L K GA N D+ G + +H Sbjct: 227 KQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHR 286 Query: 81 AARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRD 136 AA G L T ++L+ +G+D ++ G A Q G+ AV L+ + + D Sbjct: 287 AALAGHLQTCRLLLSYGSDPSIISLQG----FTAAQMGNEAVQQILSESTPMRTSD 338 >4O1O-A nrPDB Length = 717 Score = 45.8 bits (107), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 49/168 (29%), Positives = 76/168 (45%), Gaps = 14/168 (8%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQ--VMMFGSTAIALELLKQGASPNV 69 L+ A D+++VR+LL R +G + L V M +AL LLK GA P + Sbjct: 12 LTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVAL-LLKHGADPCL 70 Query: 70 QDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL--- 126 + +G +P A TG + L++L+ + DVN D G A G + FL Sbjct: 71 RKRNGATPFIIAGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYEN 130 Query: 127 AAESDLHRRDAR--------GLTPLELALQRGAQDLVDILQGHMVAPL 166 A+ ++HR+ + G T L A ++G +V IL M A + Sbjct: 131 GADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEV 178 Score = 31.6 bits (70), Expect = 0.16, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 2/70 (2%) Query: 91 KVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAES--DLHRRDARGLTPLELALQ 148 ++L++HGADVNV P+ LAV+ + +V L + +++ D G T L LA++ Sbjct: 206 RLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVE 265 Query: 149 RGAQDLVDIL 158 +++ +L Sbjct: 266 LRLEEIAKLL 275 >5DND-A nrPDB Length = 588 Score = 45.4 bits (106), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 33/101 (32%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 +VQD S A G L+ L+ L+E G+D+ + D G +H+A + G VV+ L Sbjct: 416 SVQDAVMPSLALALAHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLL 475 Query: 128 AES-DLHRRDARGLTPLELALQRGAQDLVDILQ--GHMVAP 165 D++ RD GL+PL LA+Q ++ + +L+ G ++P Sbjct: 476 HRGMDVNARDRDGLSPLLLAVQGRHRECIRLLRKAGACLSP 516 Score = 39.7 bits (91), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%) Query: 60 LLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGH 119 L++ G+ ++D++G + +H AAR G + +L+ G DVN D G P+ LAVQ H Sbjct: 441 LMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGLSPLLLAVQGRH 500 Query: 120 TAVVSFLAAESDLHRRDARGLTPLEL 145 + L R+ L+P +L Sbjct: 501 RECIRLL-------RKAGACLSPQDL 519 >4OAU-C nrPDB Length = 699 Score = 44.3 bits (103), Expect = 2e-05, Method: Composition-based stats. Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 2/85 (2%) Query: 59 ELLKQGASPNVQDTSGT-SPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQE 117 +LL+ GA+ N Q+ G +P+H+A + D +++L+ HGAD + GA P LA Sbjct: 23 QLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFILAAIA 82 Query: 118 GHTAVVS-FLAAESDLHRRDARGLT 141 G ++ FL+ +D++ D G T Sbjct: 83 GSVKLLKLFLSKGADVNECDFYGFT 107 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 11/116 (9%) Query: 60 LLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGH 119 LL+ GA P ++ +G +P AA G + LK+ + GADVN D G A G Sbjct: 58 LLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGK 117 Query: 120 TAVVSFL---AAESDLHRRDAR--------GLTPLELALQRGAQDLVDILQGHMVA 164 + FL A +L R+ G T L A ++G +++ IL M A Sbjct: 118 VKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGA 173 Score = 39.7 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 2/69 (2%) Query: 92 VLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAES--DLHRRDARGLTPLELALQR 149 +L++HGADVNV G P+ LAV++ H +V L + +++ D+ G T L LA++ Sbjct: 204 LLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVEL 263 Query: 150 GAQDLVDIL 158 + + ++L Sbjct: 264 KLKKIAELL 272 Score = 35.8 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 39/139 (28%), Positives = 60/139 (43%), Gaps = 13/139 (9%) Query: 22 QEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL-LKQGASPNVQDTSGTSPVHD 80 +++ LL R P + G T + + L+L L +GA N D G + + Sbjct: 52 EDIVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFME 111 Query: 81 AARTGFLDTLKVLVEHGADVNVPDGT----------GALPIHLAVQEGHTAVVSFLAAE- 129 AA G + LK L + GA+VN+ T GA + A ++GH V+ L E Sbjct: 112 AAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEM 171 Query: 130 -SDLHRRDARGLTPLELAL 147 +D++ D G L AL Sbjct: 172 GADVNACDNMGRNALIHAL 190 >3ZKJ-A nrPDB Length = 261 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 28/100 (28%), Positives = 47/100 (47%) Query: 59 ELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEG 118 L+ QG + N+ SP+H+A G L +K+L++HGA VN P+ A G Sbjct: 21 NLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSG 80 Query: 119 HTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDIL 158 V+ L + ++ +P+ A +RG + V+ L Sbjct: 81 SWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVNSL 120 Score = 40.4 bits (93), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Query: 73 SGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SD 131 S SP+H+AA G +L+ L+ G VN+ P+H A GH + V L + Sbjct: 2 SDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQ 61 Query: 132 LHRRDARGLTPLELALQRGAQDLVDILQGH 161 ++ A TPL A G+ D V++L H Sbjct: 62 VNGVTADWHTPLFNACVSGSWDCVNLLLQH 91 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 5/109 (4%) Query: 52 GSTAIALELLKQGASPNVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALP 110 GS LL+ GAS VQ S SP+H+AAR G ++ + L+ +G +++ P Sbjct: 80 GSWDCVNLLLQHGAS--VQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTP 137 Query: 111 IHLAVQEGHTAVV-SFLAAESDLHRRDARGLTPLELALQRGAQDLVDIL 158 ++LA + A V L + +D+++ + +PL + +++L +L Sbjct: 138 LYLACENQQRACVKKLLESGADVNQGKGQD-SPLHAVARTASEELACLL 185 Score = 32.0 bits (71), Expect = 0.12, Method: Compositional matrix adjust. Identities = 29/103 (28%), Positives = 42/103 (40%), Gaps = 1/103 (0%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSG 74 AA RG V+ V L+ ++ G A +LL+ GA N Q Sbjct: 108 AARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVN-QGKGQ 166 Query: 75 TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQE 117 SP+H ART + +L++ GAD + G P+ L E Sbjct: 167 DSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELVPPE 209 >6EMK-G nrPDB Length = 426 Score = 43.5 bits (101), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 44/157 (28%), Positives = 71/157 (45%), Gaps = 12/157 (7%) Query: 11 RLSGAAARGDVQEVRRLLHRELVHPDALNRF----GKTALQVMMF-GSTAIALELLKQGA 65 RL A G++ V+RLL R +PD L G ++L + G I + L++ G Sbjct: 8 RLREAIIEGNLLIVKRLLRR---NPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGH 64 Query: 66 SPN--VQDTSGTSPVHDAARTGFLDTLKVLVEHGAD-VNVPDGTGALPIHLAVQEGHTAV 122 + ++ G + VH A G TL +L++ +N G PIH+A + Sbjct: 65 DKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQC 124 Query: 123 VSFL-AAESDLHRRDARGLTPLELALQRGAQDLVDIL 158 +S L +DL D G TPL + L+ G+ + +L Sbjct: 125 LSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKML 161 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 4/78 (5%) Query: 73 SGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDL 132 +G +P+H A + L +L+ GAD+ V D G P+H+ ++ G + + L E ++ Sbjct: 108 NGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEV 167 Query: 133 ----HRRDARGLTPLELA 146 + RD P+++A Sbjct: 168 SLDDNVRDKGNWKPIDVA 185 >1WG0-A nrPDB Length = 243 Score = 43.5 bits (101), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Query: 72 TSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA--AE 129 G + +H A + + + L+E+GA V + D +P+H A G ++ L + Sbjct: 105 NQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGK 164 Query: 130 SDLHRRDARGLTPLELALQRGAQD 153 S ++ +D +G TPL AL G D Sbjct: 165 SAVNWQDKQGWTPLFHALAEGHGD 188 Score = 34.3 bits (77), Expect = 0.026, Method: Compositional matrix adjust. Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 6/95 (6%) Query: 70 QDTSGTSPVHDAARTGFLDTLKVLVEHGADVNV---PDGTGALPIHLAVQEGHTAVVSFL 126 +D G P+H + + L+ +VN+ PD +G P H+A G+ VV L Sbjct: 32 KDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSL 91 Query: 127 A---AESDLHRRDARGLTPLELALQRGAQDLVDIL 158 + DL++ +G+T L LA+ + ++ L Sbjct: 92 YDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFL 126 >4OT9-A nrPDB Length = 359 Score = 42.0 bits (97), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 40/117 (34%), Positives = 62/117 (52%), Gaps = 8/117 (6%) Query: 43 KTALQVMMFGSTAIALELLK-QGASPNVQDTSGTSPVHDA---ARTGFLDTLKVLVEHGA 98 ++A ++ +G TA A LL Q QD +G +P+H A +T ++ + ++ H Sbjct: 50 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 109 Query: 99 DVNVPDGTGAL---PIHLAVQEGHTAVVSF-LAAESDLHRRDARGLTPLELALQRGA 151 D+ V + T L P+HLAV G T+VVSF L +D D G + + LAL+ GA Sbjct: 110 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGA 166 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 11/135 (8%) Query: 35 PDALNRFGKTALQVMM---FGSTAIALELLKQGASPNVQ-----DTSGTSPVHDAARTGF 86 P L+R G +A+ + + G+ + LL+ GA Q D G PVH A R Sbjct: 147 PALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARS 206 Query: 87 LDTLKVLVEHGADVNVPDGTGA-LPIHLAVQEGHTAVVSFLAAE--SDLHRRDARGLTPL 143 + L +LV+ GA+V + G +HLA + +V+ L + ++++ R G TPL Sbjct: 207 PECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPL 266 Query: 144 ELALQRGAQDLVDIL 158 LA G L +L Sbjct: 267 HLAAGLGYPTLTRLL 281 Score = 28.9 bits (63), Expect = 1.00, Method: Compositional matrix adjust. Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 20/114 (17%) Query: 62 KQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTA 121 K A+ N + +G +P+H AA G+ ++L++ GAD IH +E Sbjct: 250 KLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGAD-----------IHAENEEPLCP 298 Query: 122 VVSFLAAESDLH--------RRDARGLTPLELALQRGAQD-LVDILQGHMVAPL 166 + S ++SD R RG TPL+L + L++ Q M PL Sbjct: 299 LPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPL 352 >5UQE-A nrPDB Length = 520 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 2/85 (2%) Query: 81 AARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL--AAESDLHRRDAR 138 AA TG + L+ D+ D +H+A EGH VV FL A + + +D Sbjct: 424 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 483 Query: 139 GLTPLELALQRGAQDLVDILQGHMV 163 TP++ AL G D+ ILQ + V Sbjct: 484 NNTPMDEALHFGHHDVFKILQEYQV 508 >3LJN-A nrPDB Length = 364 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 71 DTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAES 130 D +H AAR G D ++ L+E G + + G +HLA + G +LA+ Sbjct: 17 DDENMEKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG 76 Query: 131 DLHRRDARGLTPLELALQRGAQDLV 155 ++H G P+ LA+ DLV Sbjct: 77 EVHSL-WHGQKPIHLAVMANKTDLV 100 Score = 39.3 bits (90), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Query: 52 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPI 111 G T L++ G SP +Q+ G + +H A + G +DT K L G ++ G PI Sbjct: 31 GQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVGEVHSL--WHGQKPI 88 Query: 112 HLAVQEGHTAVV 123 HLAV T +V Sbjct: 89 HLAVMANKTDLV 100 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSTAIALELLKQGASPN 68 +++ AA +G EVRRL+ V P NRFG TAL + FG A L G + Sbjct: 22 EKIHVAARKGQTDEVRRLIETG-VSPTIQNRFGCTALHLACKFGCVDTAKYLASVGEVHS 80 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVE 95 + G P+H A D + LVE Sbjct: 81 LW--HGQKPIHLAVMANKTDLVVALVE 105 Score = 32.3 bits (72), Expect = 0.099, Method: Compositional matrix adjust. Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 6/104 (5%) Query: 35 PDALNRFGKTALQVMMFGSTAIALELL------KQGASPNVQDTSGTSPVHDAARTGFLD 88 P A ++ +T L M AL+L+ K + + G S +H A + D Sbjct: 166 PTAKDKADETPLMRAMEFRNREALDLMMDTVPSKSSLRLDYANKQGNSHLHWAILINWED 225 Query: 89 TLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDL 132 VE G DVN+ D +P++L+V+ + L ++D+ Sbjct: 226 VAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLTKELLQKTDV 269 >5U0J-A nrPDB Length = 140 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 2/85 (2%) Query: 81 AARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL--AAESDLHRRDAR 138 AA TG + L+ D+ D +H+A EGH VV FL A + + +D Sbjct: 31 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 90 Query: 139 GLTPLELALQRGAQDLVDILQGHMV 163 TP++ AL G D+ ILQ + V Sbjct: 91 NNTPMDEALHFGHHDVFKILQEYQV 115 >6E2G-A nrPDB Length = 727 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 25/130 (19%) Query: 42 GKTALQVMMFGSTA-IALELLKQGASPNVQDTS-------------GTSPVHDAARTGFL 87 G+TAL + + + LL +GAS + + T G P+ AA G Sbjct: 117 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 176 Query: 88 DTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-----FLAAESDLHRR------D 136 + +++L+EHGAD+ D G +H+ + + + L+ + H + + Sbjct: 177 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPN 236 Query: 137 ARGLTPLELA 146 +GLTP +LA Sbjct: 237 NQGLTPFKLA 246 >5U0K-A nrPDB Length = 141 Score = 36.6 bits (83), Expect = 0.005, Method: Compositional matrix adjust. Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 81 AARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL--AAESDLHRRDAR 138 AA +G + L+ D+ D +H+A EGH VV FL A + + +D Sbjct: 32 AAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRW 91 Query: 139 GLTPLELALQRGAQDLVDILQGH 161 G PL+ A+Q ++V +LQ + Sbjct: 92 GNIPLDDAVQFNHLEVVKLLQDY 114 Score = 30.8 bits (68), Expect = 0.27, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 3/66 (4%) Query: 70 QDTSGTSPVHDAARTGFLDTLKVLVEHGADVN--VPDGTGALPIHLAVQEGHTAVVSFLA 127 +D + +H AA G ++ +K L+E VN D G +P+ AVQ H VV L Sbjct: 54 KDYDSRTALHVAAAEGHIEVVKFLIE-ACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLLQ 112 Query: 128 AESDLH 133 D + Sbjct: 113 DYQDSY 118 >5IRX-A nrPDB Length = 636 Score = 35.8 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 56/196 (28%), Positives = 76/196 (38%), Gaps = 51/196 (26%) Query: 7 RAGDRLS--GAAARGDVQEV-----------RRLLHRELVHPDALNRFGKTALQVMMFG- 52 R DR S A A+ + QE+ +RL E P+ GKT L M Sbjct: 5 RLYDRRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPET----GKTCLLKAMLNL 60 Query: 53 ----STAIALEL--------LKQGASPNVQDT--SGTSPVHDAARTGFLDTLKVLVEHGA 98 + IAL L LKQ + + D+ G + +H A + + +LVE+GA Sbjct: 61 HNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGA 120 Query: 99 DVNVPDGT--------------GALPIHLAVQEGHTAVVSFLAAES----DLHRRDARGL 140 DV G LP+ LA A+V FL S D+ RD+ G Sbjct: 121 DVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGN 180 Query: 141 TPLELALQRGAQDLVD 156 T L AL A + VD Sbjct: 181 TVLH-ALVEVADNTVD 195 >2RFA-A nrPDB Length = 232 Score = 35.4 bits (80), Expect = 0.012, Method: Compositional matrix adjust. Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 25/130 (19%) Query: 42 GKTALQVMMFGSTA-IALELLKQGASPNVQDT-------------SGTSPVHDAARTGFL 87 G+TAL + + + LL +GAS + + T G P+ AA G Sbjct: 75 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 134 Query: 88 DTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-----FLAAESDLHRR------D 136 + +++L+EHGAD+ D G +H+ + + + L+ + H + + Sbjct: 135 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPN 194 Query: 137 ARGLTPLELA 146 +GLTP +LA Sbjct: 195 NQGLTPFKLA 204 >6DMR-A nrPDB Length = 730 Score = 34.3 bits (77), Expect = 0.023, Method: Compositional matrix adjust. Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 26/131 (19%) Query: 42 GKTALQV-MMFGSTAIALELLKQGASPNVQDT-------------SGTSPVHDAARTGFL 87 G+TAL + +M + + LL +GAS + + T G P+ AA G Sbjct: 117 GQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSE 176 Query: 88 DTLKVLVEHGADVNVPDGTGALPIH-LAVQEGHTAVVSF--LAAESDLHRR--------- 135 + +++L+EHGAD+ D G +H L +Q T L D H Sbjct: 177 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVP 236 Query: 136 DARGLTPLELA 146 + +GLTP +LA Sbjct: 237 NHQGLTPFKLA 247 >2NYJ-A nrPDB Length = 273 Score = 34.3 bits (77), Expect = 0.026, Method: Compositional matrix adjust. Identities = 56/196 (28%), Positives = 76/196 (38%), Gaps = 51/196 (26%) Query: 7 RAGDRLS--GAAARGDVQEV-----------RRLLHRELVHPDALNRFGKTALQVMMFG- 52 R DR S A A+ + QE+ +RL E P+ GKT L M Sbjct: 10 RLYDRRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPET----GKTCLLKAMLNL 65 Query: 53 ----STAIALEL--------LKQGASPNVQDT--SGTSPVHDAARTGFLDTLKVLVEHGA 98 + IAL L LKQ + + D+ G + +H A + + +LVE+GA Sbjct: 66 HNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGA 125 Query: 99 DVNVPDG--------------TGALPIHLAVQEGHTAVVSFLAAES----DLHRRDARGL 140 DV G LP+ LA A+V FL S D+ RD+ G Sbjct: 126 DVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGN 185 Query: 141 TPLELALQRGAQDLVD 156 T L AL A + VD Sbjct: 186 TVLH-ALVEVADNTVD 200 >3DEO-A nrPDB Length = 183 Score = 33.9 bits (76), Expect = 0.034, Method: Compositional matrix adjust. Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 20/150 (13%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELLKQGASPNVQDT- 72 AA + D Q + +LL V DA++ G+TAL V GS L + GA + +D Sbjct: 51 AARKADEQALSQLLEDRDV--DAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMR 108 Query: 73 SGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDL 132 G + +H AA + ++ LVE GAD+ V D G + LA ++ Sbjct: 109 GGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA---------------REI 153 Query: 133 HRRDARGLTPLELALQRGAQDLVDILQGHM 162 + +G P++ + G + ++++L+G + Sbjct: 154 LKTTPKG-NPMQFGRRIGLEKVINVLEGQV 182 >3UI2-A nrPDB Length = 244 Score = 33.9 bits (76), Expect = 0.035, Method: Compositional matrix adjust. Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 20/150 (13%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELLKQGASPNVQDT- 72 AA + D Q + +LL V DA++ G+TAL V GS L + GA + +D Sbjct: 52 AARKADEQALSQLLEDRDV--DAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMR 109 Query: 73 SGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDL 132 G + +H AA + ++ LVE GAD+ V D G + LA ++ Sbjct: 110 GGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA---------------REI 154 Query: 133 HRRDARGLTPLELALQRGAQDLVDILQGHM 162 + +G P++ + G + ++++L+G + Sbjct: 155 LKTTPKG-NPMQFGRRIGLEKVINVLEGQV 183 >6CV9-A nrPDB Length = 842 Score = 31.2 bits (69), Expect = 0.22, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 8/85 (9%) Query: 80 DAARTGFLDTLKVLVE--HGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHR-RD 136 DAA G + ++ ++E H +VN D G + LAV H + L + +L R D Sbjct: 15 DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD 74 Query: 137 ARGLTPLELALQRGAQDLVDILQGH 161 A L LA+ +G +V+ + H Sbjct: 75 A-----LLLAISKGYVRIVEAILNH 94 >2ETB-A nrPDB Length = 256 Score = 31.2 bits (69), Expect = 0.24, Method: Compositional matrix adjust. Identities = 45/152 (29%), Positives = 61/152 (40%), Gaps = 35/152 (23%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALN-------RFGKTALQVMMF----GSTAIAL 58 DRL +RG +E+ LL + L GKT L + G A + Sbjct: 4 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 63 Query: 59 ELL---KQGASP----NVQDT----SGTSPVHDAARTGFLDTLKVLVEHGADVNVP---- 103 LL K +P N Q T G S +H A L +K+LVE+GADV++ Sbjct: 64 PLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 123 Query: 104 -----DGT----GALPIHLAVQEGHTAVVSFL 126 GT G LP+ LA VV++L Sbjct: 124 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYL 155 >6BOA-A nrPDB Length = 742 Score = 30.4 bits (67), Expect = 0.33, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 12/85 (14%) Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIH-LAVQEGHTAVVSF--LAAES 130 G P+ AA + +++L+EHGAD+ D G +H L +Q T L Sbjct: 163 GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 222 Query: 131 DLHRR---------DARGLTPLELA 146 D H + +GLTP +LA Sbjct: 223 DRHGDHLQPLDLVPNHQGLTPFKLA 247 >6BO5-A nrPDB Length = 695 Score = 29.6 bits (65), Expect = 0.65, Method: Composition-based stats. Identities = 45/152 (29%), Positives = 61/152 (40%), Gaps = 35/152 (23%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALN-------RFGKTALQVMMF----GSTAIAL 58 DRL +RG +E+ LL + L GKT L + G A + Sbjct: 38 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 97 Query: 59 ELL---KQGASP----NVQDT----SGTSPVHDAARTGFLDTLKVLVEHGADVNVP---- 103 LL K +P N Q T G S +H A L +K+LVE+GADV++ Sbjct: 98 PLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 157 Query: 104 -----DGT----GALPIHLAVQEGHTAVVSFL 126 GT G LP+ LA VV++L Sbjct: 158 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYL 189 >5HI9-A nrPDB Length = 770 Score = 29.6 bits (65), Expect = 0.65, Method: Composition-based stats. Identities = 45/152 (29%), Positives = 61/152 (40%), Gaps = 35/152 (23%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALN-------RFGKTALQVMMF----GSTAIAL 58 DRL +RG +E+ LL + L GKT L + G A + Sbjct: 78 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 137 Query: 59 ELL---KQGASP----NVQDT----SGTSPVHDAARTGFLDTLKVLVEHGADVNVP---- 103 LL K +P N Q T G S +H A L +K+LVE+GADV++ Sbjct: 138 PLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 197 Query: 104 -----DGT----GALPIHLAVQEGHTAVVSFL 126 GT G LP+ LA VV++L Sbjct: 198 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYL 229 >3W9G-A nrPDB Length = 260 Score = 28.9 bits (63), Expect = 1.2, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 18/88 (20%) Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNV--------PDGTGA------LPIHLAVQEGH 119 G + +H A +++LVE GADV+ P G LP+ LA Sbjct: 93 GQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 152 Query: 120 TAVVSFLA----AESDLHRRDARGLTPL 143 +V +L ++DL R+D+RG T L Sbjct: 153 PHIVHYLTENGHKQADLRRQDSRGNTVL 180 >5UIL-A nrPDB Length = 405 Score = 28.5 bits (62), Expect = 1.4, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 30/59 (50%) Query: 43 KTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVN 101 K L+ + + +L++ + ++ G SPV AA G ++ +K LV GA++N Sbjct: 280 KEILEACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGANIN 338 >6CUD-A nrPDB Length = 806 Score = 28.5 bits (62), Expect = 1.5, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 6/84 (7%) Query: 80 DAARTGFLDTLKVLVEHGA--DVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDA 137 DAA G + ++ ++E +VN D G + LAV H V L + +L A Sbjct: 33 DAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENL----A 88 Query: 138 RGLTPLELALQRGAQDLVDILQGH 161 R L LA+ +G +V+ + H Sbjct: 89 RIGDALLLAISKGYVRIVEAILNH 112 >5V8F-9 nrPDB Length = 513 Score = 27.7 bits (60), Expect = 2.3, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 3/74 (4%) Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 +V S + +++ FL T +L + VN+ GALP A E V++FLA Sbjct: 37 DVTPESSPEKLQFGSQSIFLRTKALLQKSSELVNLNSSDGALPARTAEYE---QVMNFLA 93 Query: 128 AESDLHRRDARGLT 141 HR D+ +T Sbjct: 94 KAISEHRSDSLYIT 107 >2F37-A nrPDB Length = 251 Score = 27.7 bits (60), Expect = 2.5, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 13/66 (19%) Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVP---------DGT----GALPIHLAVQEGHT 120 G S +H A L +K+LVE+GA+V+ GT G LP+ LA Sbjct: 95 GHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQW 154 Query: 121 AVVSFL 126 VVS+L Sbjct: 155 DVVSYL 160 >5IMY-A nrPDB Length = 490 Score = 27.7 bits (60), Expect = 2.8, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Query: 84 TGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDL 132 TG +DTLK L++ GA N+ + A+PI V+ L + SD Sbjct: 323 TGNIDTLKALIQEGA--NLSTSSPAVPIAYTTSFVKDNEVATLQSNSDY 369 >6DQP-A nrPDB Length = 190 Score = 27.3 bits (59), Expect = 3.2, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 3/61 (4%) Query: 76 SPVHDAARTGFLDTLKVLVEHGA---DVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDL 132 +PV+ AA +G L TL L+ A V +P TG HL + V+S L A+ L Sbjct: 74 TPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDALKPVLSALKAQEIL 133 Query: 133 H 133 H Sbjct: 134 H 134 >4Q1T-A nrPDB Length = 376 Score = 27.3 bits (59), Expect = 3.4, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 5/79 (6%) Query: 92 VLVEHGA-DVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELA---- 146 V+++ GA D G LPI + +G A +A +D R ARG+T A Sbjct: 287 VVIDAGAVDKLTAGGKSLLPIGVVAVQGVFARGEVIACVNDAGREVARGITNYSSAEAKL 346 Query: 147 LQRGAQDLVDILQGHMVAP 165 +QR ++ + G+M+ P Sbjct: 347 IQRKPSGEIEAVLGYMLEP 365 >3ERJ-A nrPDB Length = 123 Score = 27.3 bits (59), Expect = 3.4, Method: Compositional matrix adjust. Identities = 10/24 (41%), Positives = 16/24 (66%) Query: 112 HLAVQEGHTAVVSFLAAESDLHRR 135 LAVQ H A++ +L ++S L R+ Sbjct: 19 KLAVQVAHAAIIGYLKSDSSLRRK 42 >6MHW-A nrPDB Length = 826 Score = 27.3 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 14/96 (14%) Query: 74 GTSPVHDAARTGFLDTLKVLVEH-GADVNVPDGTGALPIH--LAVQEGHTAVVSFLAAES 130 G +P+ AA T + +++L+EH D+ D G +H + V E F+ Sbjct: 263 GETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMY 322 Query: 131 DL-----------HRRDARGLTPLELALQRGAQDLV 155 D+ R+ GLTPL+LA + G +++ Sbjct: 323 DMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEIL 358 >6DJS-A nrPDB Length = 676 Score = 27.3 bits (59), Expect = 3.6, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 6/84 (7%) Query: 80 DAARTGFLDTLKVLVEHGA--DVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDA 137 DAA G + ++ ++E +VN D G + LAV H V L + +L A Sbjct: 50 DAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENL----A 105 Query: 138 RGLTPLELALQRGAQDLVDILQGH 161 R L LA+ +G +V+ + H Sbjct: 106 RIGDALLLAISKGYVRIVEAILNH 129 >6OGN-A nrPDB Length = 692 Score = 26.9 bits (58), Expect = 4.1, Method: Composition-based stats. Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 6/35 (17%) Query: 77 PVHDAA-----RTGFLDTLKVLVEHGADVNV-PDG 105 P+ +AA R GF D +KV+ +H +V V PDG Sbjct: 98 PMAEAAVKIVERNGFSDKIKVINKHSTEVTVGPDG 132 >5C70-A nrPDB Length = 612 Score = 25.8 bits (55), Expect = 8.7, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 15/29 (51%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDAL 38 DR++ Q +R L+HR+ HP + Sbjct: 387 DRINNKTREAHAQAIRELIHRDKNHPSVV 415 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1BLX-B nrPDB 197 2e-51 5AQB-A nrPDB 190 2e-49 5MIO-C nrPDB 185 1e-47 6MWQ-A nrPDB 184 2e-47 1BD8-A nrPDB 183 3e-47 5AQ9-A nrPDB 180 2e-46 6FES-A nrPDB 175 1e-44 5AQA-A nrPDB 172 5e-44 5H76-A nrPDB 170 3e-43 5AQ7-A nrPDB 168 1e-42 4Z68-A nrPDB 151 2e-37 6EMK-G nrPDB 142 1e-34 4O1O-A nrPDB 141 2e-34 5GP7-A nrPDB 140 3e-34 5CBO-A nrPDB 139 4e-34 1G3N-B nrPDB 136 4e-33 6BY9-A nrPDB 131 2e-31 4OAU-C nrPDB 130 4e-31 5JHQ-A nrPDB 128 1e-30 5HKP-A nrPDB 127 2e-30 4NIK-A nrPDB 125 1e-29 5ET1-A nrPDB 123 3e-29 2DWZ-A nrPDB 121 1e-28 3B7B-A nrPDB 120 2e-28 3ZKJ-A nrPDB 115 9e-27 2A5E-A nrPDB 115 1e-26 1D9S-A nrPDB 112 7e-26 1WG0-A nrPDB 109 6e-25 6AUN-A nrPDB 108 1e-24 3EU9-A nrPDB 106 6e-24 5D68-A nrPDB 103 4e-23 3T9K-A nrPDB 100 5e-22 6E2G-A nrPDB 97 4e-21 5UQE-A nrPDB 93 5e-20 4OT9-A nrPDB 89 7e-19 5DND-A nrPDB 89 9e-19 2KXP-C nrPDB 88 2e-18 5U0J-A nrPDB 86 7e-18 3LJN-A nrPDB 82 1e-16 Sequences not found previously or not previously below threshold: 6DMR-A nrPDB 90 3e-19 5U0K-A nrPDB 86 7e-18 6BOA-A nrPDB 85 1e-17 2RFA-A nrPDB 85 1e-17 3EHQ-A nrPDB 75 1e-14 5AN8-A nrPDB 69 1e-12 3UI2-A nrPDB 68 1e-12 3DEO-A nrPDB 67 3e-12 5IRX-A nrPDB 67 3e-12 6OO7-A nrPDB 67 4e-12 6BO5-A nrPDB 66 9e-12 5HI9-A nrPDB 66 9e-12 2NYJ-A nrPDB 64 4e-11 4BSZ-B nrPDB 63 5e-11 6DVZ-A nrPDB 63 6e-11 3W9G-A nrPDB 61 3e-10 1DCQ-A nrPDB 60 4e-10 2ETB-A nrPDB 60 6e-10 3LVQ-E nrPDB 59 9e-10 4N5Q-A nrPDB 59 1e-09 6C8G-A nrPDB 59 1e-09 6BBJ-A nrPDB 59 1e-09 4DX2-A nrPDB 58 3e-09 2F37-A nrPDB 57 3e-09 5UIL-A nrPDB 57 4e-09 2B0O-E nrPDB 57 5e-09 6CV9-A nrPDB 52 9e-08 6MHW-A nrPDB 51 2e-07 6CUD-A nrPDB 49 8e-07 4XD0-A nrPDB 48 1e-06 6DJS-A nrPDB 47 4e-06 6G1K-A nrPDB 45 1e-05 5Z96-A nrPDB 35 0.014 5XE7-A nrPDB 31 0.23 4P98-A nrPDB 29 0.84 3NA5-A nrPDB 28 1.9 4CJ9-A nrPDB 28 2.3 1OH2-P nrPDB 27 3.3 1EV4-A nrPDB 27 3.7 5A9Q-4 nrPDB 26 5.4 2DI3-A nrPDB 26 5.7 2X7Q-A nrPDB 26 7.1 5KQW-A nrPDB 26 8.3 6NJ0-A nrPDB 26 9.4 >1BLX-B nrPDB Length = 166 Score = 197 bits (501), Expect = 2e-51, Method: Composition-based stats. Identities = 144/166 (86%), Positives = 154/166 (92%) Query: 1 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL 60 MLLEEV GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGS A+ALEL Sbjct: 1 MLLEEVCVGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALEL 60 Query: 61 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT 120 LKQGASPNVQD SGTSPVHDAARTGFLDTLKVLVEHGADVN D TG+LPIHLA++EGH+ Sbjct: 61 LKQGASPNVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHS 120 Query: 121 AVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL 166 +VVSFLA ESDLH RDA GLTPLELA QRGAQ+L+DILQGHM+ P+ Sbjct: 121 SVVSFLAPESDLHHRDASGLTPLELARQRGAQNLMDILQGHMMIPM 166 >5AQB-A nrPDB Length = 428 Score = 190 bits (483), Expect = 2e-49, Method: Composition-based stats. Identities = 56/151 (37%), Positives = 83/151 (54%), Gaps = 2/151 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPN 68 G +L AA G E R L+ +AL+ G T L + +G I LLK GA N Sbjct: 15 GKKLLEAARAGQDDECRILMANG-ADVNALDEVGWTPLHLAAWGHLEIVECLLKNGADVN 73 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 128 D G +P+H AA +G L+ ++VL+++GADVN D G P+HLA GH +V L Sbjct: 74 AADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLK 133 Query: 129 -ESDLHRRDARGLTPLELALQRGAQDLVDIL 158 +D++ +D G TP +LA+ G +D+ ++L Sbjct: 134 NGADVNAQDKFGKTPRDLAIDNGNEDIAEVL 164 Score = 94.6 bits (234), Expect = 2e-20, Method: Composition-based stats. Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 2/88 (2%) Query: 78 VHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVV-SFLAAESDLHRRD 136 + +AAR G D ++L+ +GADVN D G P+HLA GH +V L +D++ D Sbjct: 18 LLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAA-WGHLEIVECLLKNGADVNAAD 76 Query: 137 ARGLTPLELALQRGAQDLVDILQGHMVA 164 G TPL LA G ++V++L + Sbjct: 77 IDGYTPLHLAAFSGHLEIVEVLLKYGAD 104 Score = 78.5 bits (192), Expect = 1e-15, Method: Composition-based stats. Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 6/109 (5%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTS 73 AA G ++ V LL +A ++ G T L + FG I LLK GA N QD Sbjct: 86 AAFSGHLEIVEVLLKYG-ADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVNAQDKF 144 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAV 122 G +P A G D +VL + V V D L + G+ + Sbjct: 145 GKTPRDLAIDNGNEDIAEVLGKAATLVKVKDAADQ----LGARVGYIEL 189 >5MIO-C nrPDB Length = 573 Score = 185 bits (469), Expect = 1e-47, Method: Composition-based stats. Identities = 55/154 (35%), Positives = 82/154 (53%), Gaps = 3/154 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASP 67 G +L AA G EVR L+ +A + G T L + +G I LLK GA Sbjct: 411 GKKLLEAARAGQDDEVRVLMANG-ADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADV 469 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FL 126 + D G++P+H AA G L+ ++VL++HGADVN D G P+ LA GH +V L Sbjct: 470 SASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALL 529 Query: 127 AAESDLHRRDARGLTPLELALQRGAQDLVDILQG 160 +D++ +D G T + ++ G++DL +ILQ Sbjct: 530 KHGADVNAQDKFGKTAYDTSIDNGSEDLAEILQK 563 Score = 150 bits (379), Expect = 2e-37, Method: Composition-based stats. Identities = 46/126 (36%), Positives = 64/126 (50%), Gaps = 1/126 (0%) Query: 40 RFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD 99 GK L+ G L+ GA N D SG +P+H AA G L+ ++VL++HGAD Sbjct: 409 DLGKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGAD 468 Query: 100 VNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLHRRDARGLTPLELALQRGAQDLVDIL 158 V+ D G+ P+HLA GH +V L +D++ D G TPL LA G +V+ L Sbjct: 469 VSASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEAL 528 Query: 159 QGHMVA 164 H Sbjct: 529 LKHGAD 534 >6MWQ-A nrPDB Length = 493 Score = 184 bits (466), Expect = 2e-47, Method: Composition-based stats. Identities = 58/154 (37%), Positives = 84/154 (54%), Gaps = 3/154 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASP 67 G +L AA G EVR L+ +AL+RFG T L + G I LLK GA Sbjct: 6 GKKLLEAARAGQDDEVRILMANG-ADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADV 64 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 N D G +P+H AA G L+ ++VL+++GADVN D G P+HL +GH +V L Sbjct: 65 NAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLL 124 Query: 128 AE-SDLHRRDARGLTPLELALQRGAQDLVDILQG 160 +D++ +D G T ++++ G +DL +ILQ Sbjct: 125 KHGADVNAQDKFGKTAFDISIDNGNEDLAEILQK 158 Score = 145 bits (367), Expect = 7e-36, Method: Composition-based stats. Identities = 44/126 (34%), Positives = 63/126 (50%), Gaps = 1/126 (0%) Query: 40 RFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD 99 GK L+ G L+ GA N D G +P+H AA+ G L+ ++VL++ GAD Sbjct: 4 DLGKKLLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGAD 63 Query: 100 VNVPDGTGALPIHLAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQRGAQDLVDIL 158 VN D G P+HLA GH +V L +D++ D G TPL L G ++V++L Sbjct: 64 VNAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVL 123 Query: 159 QGHMVA 164 H Sbjct: 124 LKHGAD 129 >1BD8-A nrPDB Length = 156 Score = 183 bits (464), Expect = 3e-47, Method: Composition-based stats. Identities = 156/156 (100%), Positives = 156/156 (100%) Query: 7 RAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGAS 66 RAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGAS Sbjct: 1 RAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGAS 60 Query: 67 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL Sbjct: 61 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 120 Query: 127 AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHM 162 AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHM Sbjct: 121 AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHM 156 Score = 47.6 bits (112), Expect = 2e-06, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 33/88 (37%), Gaps = 1/88 (1%) Query: 78 VHDAARTGFLDTLKVLVEHG-ADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRD 136 + AA G + ++ L+ + + G + + + + L + + +D Sbjct: 6 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQD 65 Query: 137 ARGLTPLELALQRGAQDLVDILQGHMVA 164 G +P+ A + G D + +L H Sbjct: 66 TSGTSPVHDAARTGFLDTLKVLVEHGAD 93 >5AQ9-A nrPDB Length = 422 Score = 180 bits (458), Expect = 2e-46, Method: Composition-based stats. Identities = 56/158 (35%), Positives = 82/158 (51%), Gaps = 3/158 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASP 67 G +L AA G EVR L+ +A + G T L + + G I LLK GA Sbjct: 15 GRKLLEAARAGQDDEVRILMANG-ADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV 73 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 + D G +P+H AA G L+ ++VL+++GADVN D G P+HLA + G+ +V L Sbjct: 74 DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLL 133 Query: 128 AE-SDLHRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 +D++ +D G TP +LA G D+ +LQ A Sbjct: 134 KHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAAA 171 >6FES-A nrPDB Length = 367 Score = 175 bits (443), Expect = 1e-44, Method: Composition-based stats. Identities = 54/157 (34%), Positives = 78/157 (49%), Gaps = 3/157 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASP 67 G +L AA G EVR LL + + G T L + + G I LLK GA Sbjct: 7 GKKLLEAARAGQDDEVRILLANG-ADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV 65 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 N D G +P+H AA TG L+ ++VL+++GA VN D G P+HLA GH +V L Sbjct: 66 NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLL 125 Query: 128 A-ESDLHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 +D +D G TP +LA G + + + + ++ Sbjct: 126 KNGADARAQDKFGKTPEDLARDNGYESVARLARKEII 162 Score = 147 bits (372), Expect = 2e-36, Method: Composition-based stats. Identities = 43/126 (34%), Positives = 63/126 (50%), Gaps = 1/126 (0%) Query: 40 RFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD 99 GK L+ G LL GA N D +G +P+H AA G L ++VL+++GAD Sbjct: 5 DLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGAD 64 Query: 100 VNVPDGTGALPIHLAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQRGAQDLVDIL 158 VN D G P+HLA GH +V L + ++ D G PL LA G +++V++L Sbjct: 65 VNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVL 124 Query: 159 QGHMVA 164 + Sbjct: 125 LKNGAD 130 >5AQA-A nrPDB Length = 418 Score = 172 bits (437), Expect = 5e-44, Method: Composition-based stats. Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 3/155 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASP 67 G +L AA G EVR L+ +A + G T L + + G I LLK GA Sbjct: 15 GRKLLEAARAGQDDEVRILMANG-ADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV 73 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FL 126 + D G +P+H AA G L+ ++VL+++GADVN D G P+HLA + G+ +V L Sbjct: 74 DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLL 133 Query: 127 AAESDLHRRDARGLTPLELALQRGAQDLVDILQGH 161 A +D+ +D G PL LA +G ++ L Sbjct: 134 KAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Score = 155 bits (391), Expect = 1e-38, Method: Composition-based stats. Identities = 44/126 (34%), Positives = 70/126 (55%), Gaps = 1/126 (0%) Query: 40 RFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD 99 G+ L+ G L+ GA N D +GT+P+H AA +G L+ ++VL++HGAD Sbjct: 13 DLGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 72 Query: 100 VNVPDGTGALPIHLAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQRGAQDLVDIL 158 V+ D G P+HLA GH +V L +D++ D+ G+TPL LA + G +++V++L Sbjct: 73 VDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVL 132 Query: 159 QGHMVA 164 Sbjct: 133 LKAGAD 138 >5H76-A nrPDB Length = 201 Score = 170 bits (431), Expect = 3e-43, Method: Composition-based stats. Identities = 52/151 (34%), Positives = 79/151 (52%), Gaps = 2/151 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASP 67 G +L AA G EVR L+ +A + G T L + + G I LLK GA Sbjct: 7 GRKLLEAARAGQDDEVRILMANG-ADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV 65 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 + D G +P+H AA G L+ ++VL+++GADVN D G P+HLA + G+ +V L Sbjct: 66 DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLL 125 Query: 128 AESDLHRRDARGLTPLELALQRGAQDLVDIL 158 ++ +D G T ++++ G +DL IL Sbjct: 126 KHGAVNAQDKFGKTAFDISIDNGNEDLAQIL 156 Score = 148 bits (375), Expect = 9e-37, Method: Composition-based stats. Identities = 45/125 (36%), Positives = 70/125 (56%), Gaps = 1/125 (0%) Query: 40 RFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD 99 G+ L+ G L+ GA N D +GT+P+H AA +G L+ ++VL++HGAD Sbjct: 5 DLGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 64 Query: 100 VNVPDGTGALPIHLAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQRGAQDLVDIL 158 V+ D G P+HLA GH +V L +D++ D+ G+TPL LA + G ++V++L Sbjct: 65 VDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVL 124 Query: 159 QGHMV 163 H Sbjct: 125 LKHGA 129 Score = 96.6 bits (239), Expect = 4e-21, Method: Composition-based stats. Identities = 33/88 (37%), Positives = 49/88 (55%), Gaps = 1/88 (1%) Query: 78 VHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLHRRD 136 + +AAR G D +++L+ +GADVN D TG P+HLA GH +V L +D+ D Sbjct: 10 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASD 69 Query: 137 ARGLTPLELALQRGAQDLVDILQGHMVA 164 G TPL LA G ++V++L + Sbjct: 70 VFGYTPLHLAAYWGHLEIVEVLLKNGAD 97 >5AQ7-A nrPDB Length = 418 Score = 168 bits (425), Expect = 1e-42, Method: Composition-based stats. Identities = 55/155 (35%), Positives = 77/155 (49%), Gaps = 3/155 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASP 67 G +L AA G EVR LL + + G T L + + G I LLK GA Sbjct: 15 GKKLLEAARAGQDDEVRILLANG-ADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV 73 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FL 126 N D G +P+H AA TG L+ ++VL+++GA VN D G P+HLA G+ +V L Sbjct: 74 NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLL 133 Query: 127 AAESDLHRRDARGLTPLELALQRGAQDLVDILQGH 161 A +D+ +D G PL LA +G ++ L Sbjct: 134 KAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Score = 142 bits (357), Expect = 9e-35, Method: Composition-based stats. Identities = 43/126 (34%), Positives = 62/126 (49%), Gaps = 1/126 (0%) Query: 40 RFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD 99 GK L+ G LL GA N D +G +P+H AA G L ++VL+++GAD Sbjct: 13 DLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGAD 72 Query: 100 VNVPDGTGALPIHLAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQRGAQDLVDIL 158 VN D G P+HLA GH +V L + ++ D G PL LA G +++V++L Sbjct: 73 VNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVL 132 Query: 159 QGHMVA 164 Sbjct: 133 LKAGAD 138 >4Z68-A nrPDB Length = 155 Score = 151 bits (381), Expect = 2e-37, Method: Composition-based stats. Identities = 46/154 (29%), Positives = 78/154 (50%), Gaps = 3/154 (1%) Query: 8 AGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGAS 66 A +L AA GDV+ V++L + V+ + T L + ++ LL+ GA Sbjct: 3 ADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGAD 62 Query: 67 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 + +D G P+H+A G + ++LV+HGA VNV D P+H A +G + L Sbjct: 63 VHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLL 122 Query: 127 AAE-SDLHRRDARGLTPLELALQRGAQDLVDILQ 159 +D +++ G TPL+L ++ G D+ D+L+ Sbjct: 123 LQHGADPTKKNRDGNTPLDL-VKDGDTDIQDLLR 155 Score = 75.4 bits (184), Expect = 1e-14, Method: Composition-based stats. Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 4/89 (4%) Query: 78 VHDAARTGFLDTLKVLVEHGADVNVPDGTGA--LPIHLAVQEGHTAVVSFLAAE-SDLHR 134 + +AA+ G ++T+K L VN D G P+H A +VV +L +D+H Sbjct: 7 LLEAAKAGDVETVKKLC-TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHA 65 Query: 135 RDARGLTPLELALQRGAQDLVDILQGHMV 163 +D GL PL A G ++ ++L H Sbjct: 66 KDKGGLVPLHNACSYGHYEVAELLVKHGA 94 >6EMK-G nrPDB Length = 426 Score = 142 bits (357), Expect = 1e-34, Method: Composition-based stats. Identities = 44/161 (27%), Positives = 71/161 (44%), Gaps = 12/161 (7%) Query: 11 RLSGAAARGDVQEVRRLLHRELVHPDALNRF----GKTALQVMMF-GSTAIALELLKQGA 65 RL A G++ V+RLL R +PD L G ++L + G I + L++ G Sbjct: 8 RLREAIIEGNLLIVKRLLRR---NPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGH 64 Query: 66 SPN--VQDTSGTSPVHDAARTGFLDTLKVLVEHGAD-VNVPDGTGALPIHLAVQEGHTAV 122 + ++ G + VH A G TL +L++ +N G PIH+A + Sbjct: 65 DKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQC 124 Query: 123 VSFL-AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHM 162 +S L +DL D G TPL + L+ G+ + +L Sbjct: 125 LSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEG 165 >4O1O-A nrPDB Length = 717 Score = 141 bits (355), Expect = 2e-34, Method: Composition-based stats. Identities = 46/167 (27%), Positives = 74/167 (44%), Gaps = 12/167 (7%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQ 70 L+ A D+++VR+LL R +G + L + S + LLK GA P ++ Sbjct: 12 LTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLR 71 Query: 71 DTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL---A 127 +G +P A TG + L++L+ + DVN D G A G + FL Sbjct: 72 KRNGATPFIIAGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENG 131 Query: 128 AESDLHRRDAR--------GLTPLELALQRGAQDLVDILQGHMVAPL 166 A+ ++HR+ + G T L A ++G +V IL M A + Sbjct: 132 ADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEV 178 Score = 83.1 bits (204), Expect = 5e-17, Method: Composition-based stats. Identities = 45/171 (26%), Positives = 67/171 (39%), Gaps = 14/171 (8%) Query: 4 EEVRAG--DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTA-----I 56 E +R G L AA +G V V LLH DA + G+ AL + I Sbjct: 145 ERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAI 204 Query: 57 ALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGA-DVNVPDGTGALPIHLAV 115 LL GA NV+ +P+ A LD +++L+E +VN D G + LAV Sbjct: 205 TRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAV 264 Query: 116 QEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAP 165 + + L + + D + +A + DLV L+ H Sbjct: 265 ELRLEEIAKLLCHRGASTNCGDL-----VAIARRNYDSDLVKFLRLHKAGE 310 Score = 79.6 bits (195), Expect = 6e-16, Method: Composition-based stats. Identities = 41/201 (20%), Positives = 76/201 (37%), Gaps = 52/201 (25%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTA-LQVMMFGSTAIALELLKQGASPNV---- 69 A G+V + +LL + + + G TA ++ ++G L + GA N+ Sbjct: 82 AGITGNV-RLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKT 140 Query: 70 -QD-----TSGTSPVHDAARTGFLDTL--------------------------------- 90 QD G + + DAA G + + Sbjct: 141 KQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGK 200 Query: 91 -----KVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA--AESDLHRRDARGLTPL 143 ++L++HGADVNV P+ LAV+ + +V L + +++ D G T L Sbjct: 201 AKAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTAL 260 Query: 144 ELALQRGAQDLVDILQGHMVA 164 LA++ +++ +L + Sbjct: 261 LLAVELRLEEIAKLLCHRGAS 281 >5GP7-A nrPDB Length = 169 Score = 140 bits (352), Expect = 3e-34, Method: Composition-based stats. Identities = 46/153 (30%), Positives = 74/153 (48%), Gaps = 5/153 (3%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQ 70 L AA +G + V++L E ++ T L + + + +A LL+ GA N Q Sbjct: 13 LLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 72 Query: 71 DTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE- 129 D G P+H+AA G +D +L+++ VN D P+H A Q+G T + + L A Sbjct: 73 DKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHG 132 Query: 130 SDLHRRDARGLTPLELALQRGAQDLVDILQGHM 162 +D ++ G TPL+LA D+ +L M Sbjct: 133 ADPTMKNQEGQTPLDLATAD---DIRALLIDAM 162 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 26/60 (43%), Gaps = 2/60 (3%) Query: 107 GALPIHLAVQEGHTAVVSFLAAESDLHRRDARGL--TPLELALQRGAQDLVDILQGHMVA 164 G + A ++G A V L +++ RD +G TPL LA ++ + L H Sbjct: 9 GDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGAD 68 >5CBO-A nrPDB Length = 176 Score = 139 bits (351), Expect = 4e-34, Method: Composition-based stats. Identities = 41/123 (33%), Positives = 66/123 (53%), Gaps = 1/123 (0%) Query: 40 RFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD 99 GK L+ G L+ GA N D G +P+H AA G + ++VL+++GAD Sbjct: 2 DLGKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGAD 61 Query: 100 VNVPDGTGALPIHLAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQRGAQDLVDIL 158 VN D TG P+HLA + G+ +V L +D++ +D G T ++++ G +DL +IL Sbjct: 62 VNASDATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEIL 121 Query: 159 QGH 161 + Sbjct: 122 CKN 124 Score = 130 bits (328), Expect = 2e-31, Method: Composition-based stats. Identities = 41/122 (33%), Positives = 63/122 (51%), Gaps = 2/122 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASP 67 G +L AA G EVR L+ +A++ FG T L + +G I LLK GA Sbjct: 4 GKKLLEAAHAGQDDEVRILMANG-ADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADV 62 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 N D +G +P+H AA+ G+L ++VL+++GADVN D G +++ G+ + L Sbjct: 63 NASDATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILC 122 Query: 128 AE 129 Sbjct: 123 KN 124 Score = 100 bits (249), Expect = 3e-22, Method: Composition-based stats. Identities = 32/88 (36%), Positives = 49/88 (55%), Gaps = 1/88 (1%) Query: 78 VHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA-ESDLHRRD 136 + +AA G D +++L+ +GADVN D G P+HLA GH +V L +D++ D Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASD 66 Query: 137 ARGLTPLELALQRGAQDLVDILQGHMVA 164 A G TPL LA + G +V++L + Sbjct: 67 ATGDTPLHLAAKWGYLGIVEVLLKYGAD 94 Score = 32.2 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 9/82 (10%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSG 74 AA G + V LL +A ++FGKTA + + E+L + Q + Sbjct: 76 AAKWGYLGIVEVLLKYG-ADVNAQDKFGKTAFDISIDNGNEDLAEILCKN---KAQQAAF 131 Query: 75 TSPVH-----DAARTGFLDTLK 91 +H +A R GF+ +LK Sbjct: 132 YCILHMPNLNEAQRNGFIQSLK 153 >1G3N-B nrPDB Length = 168 Score = 136 bits (343), Expect = 4e-33, Method: Composition-based stats. Identities = 70/157 (44%), Positives = 103/157 (65%), Gaps = 3/157 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPN 68 G+ L+ AAARGD++++ LL + +A N FG+TALQVM G+ IA LL +GA+P+ Sbjct: 6 GNELASAAARGDLEQLTSLLQNNVNV-NAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 128 ++D +G + +HDAAR GFLDTL+ L+E ADVN+ D G LP+HLA +EGH VV FL Sbjct: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 Query: 129 E--SDLHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 S++ R+ +G T +LA G ++V ++Q + Sbjct: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 >6BY9-A nrPDB Length = 328 Score = 131 bits (329), Expect = 2e-31, Method: Composition-based stats. Identities = 42/160 (26%), Positives = 78/160 (48%), Gaps = 6/160 (3%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFG--KTALQVMM-FGSTAIALELLKQGAS 66 +L +A +G++Q+V L+ + + P+ ++ L G I L++ GA+ Sbjct: 69 KQLYFSARQGELQKV-LLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGAN 127 Query: 67 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 + +P+ +AA L+ +K L++ GA V+ D G+ +HLA ++GH VV +L Sbjct: 128 IDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYL 187 Query: 127 AAES--DLHRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 + D++ +D G TP+ A + DLV +L Sbjct: 188 LSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSD 227 Score = 118 bits (296), Expect = 1e-27, Method: Composition-based stats. Identities = 41/151 (27%), Positives = 67/151 (44%), Gaps = 4/151 (2%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGA-SPNV 69 L AA ++ V+ L+ + D + G T L + G + LL G N Sbjct: 139 LMEAAENNHLEAVKYLIKAGAL-VDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNC 197 Query: 70 QDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FLAA 128 QD G +P+ A +D +K+L+ G+D+N+ D + +H A G + LAA Sbjct: 198 QDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAA 257 Query: 129 ESDLHRRDARGLTPLELALQRGAQDLVDILQ 159 + DLH + G +PL +A + D V + Sbjct: 258 KCDLHAVNIHGDSPLHIAARENRYDCVVLFL 288 Score = 115 bits (287), Expect = 1e-26, Method: Composition-based stats. Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTS 73 AA +G + V+ LL + + + G T + + + LL +G+ N++D Sbjct: 175 AAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNE 234 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FLAAESDL 132 +H AA +G +D ++L+ D++ + G P+H+A +E V FL+ +SD+ Sbjct: 235 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDV 294 Query: 133 HRRDARGLTPLELALQRGAQD 153 ++ G TPL+ A Sbjct: 295 TLKNKEGETPLQCASLNSQVW 315 >4OAU-C nrPDB Length = 699 Score = 130 bits (326), Expect = 4e-31, Method: Composition-based stats. Identities = 45/173 (26%), Positives = 67/173 (38%), Gaps = 12/173 (6%) Query: 6 VRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQG 64 V L A DV V++LL G T L + I LL+ G Sbjct: 3 VEDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHG 62 Query: 65 ASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS 124 A P ++ +G +P AA G + LK+ + GADVN D G A G + Sbjct: 63 ADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALK 122 Query: 125 FL-AAESDLHRR----------DARGLTPLELALQRGAQDLVDILQGHMVAPL 166 FL ++++ R G T L A ++G +++ IL M A + Sbjct: 123 FLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADV 175 Score = 85.8 bits (211), Expect = 9e-18, Method: Composition-based stats. Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 19/170 (11%) Query: 13 SGAAARGDVQEVRRLLHRELVHPDA----------LNRFGKTAL-QVMMFGSTAIALELL 61 AA G V+ ++ L R + + L + G TAL G + LL Sbjct: 110 MEAAVYGKVKALKFLYKRG-ANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILL 168 Query: 62 -KQGASPNVQDTSGTSPVHDAARTGFLD----TLKVLVEHGADVNVPDGTGALPIHLAVQ 116 + GA N D G + + A + +L++HGADVNV G P+ LAV+ Sbjct: 169 DEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVE 228 Query: 117 EGHTAVVSFLA--AESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 + H +V L +++ D+ G T L LA++ + + ++L + Sbjct: 229 KKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRGAS 278 Score = 48.4 bits (114), Expect = 1e-06, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 7/113 (6%) Query: 20 DVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGA-SPNVQDTSGTSP 77 DV+ + LL + GKT L + + + LL+Q N D+ G + Sbjct: 197 DVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTA 256 Query: 78 VHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAES 130 + A ++L + GA + D + A + ++V L + Sbjct: 257 LLLAVELKLKKIAELLCKRGASTDCGDL-----VMTARRNYDHSLVKVLLSHG 304 Score = 42.6 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 6/88 (6%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQ 70 L A + + V+RLL +E + + + GKTAL + + IA L K+GAS + Sbjct: 223 LILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRGASTDCG 282 Query: 71 DTSGTSPVHDAARTGFLDTLKVLVEHGA 98 D V A R +KVL+ HGA Sbjct: 283 D-----LVMTARRNYDHSLVKVLLSHGA 305 >5JHQ-A nrPDB Length = 482 Score = 128 bits (321), Expect = 1e-30, Method: Composition-based stats. Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 2/139 (1%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPN 68 D L AA G+ +++ LL V+ A + T L + + I LL+ GA + Sbjct: 170 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 229 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 128 +D G P+H+A G + ++L++HGA VN D P+H A + V S L + Sbjct: 230 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 289 Query: 129 E-SDLHRRDARGLTPLELA 146 +D + G + +++A Sbjct: 290 HGADPTLVNCHGKSAVDMA 308 Score = 126 bits (316), Expect = 5e-30, Method: Composition-based stats. Identities = 40/139 (28%), Positives = 63/139 (45%), Gaps = 2/139 (1%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPN 68 L A GDV V+RL+ V+ + + L FG + LL+ GA+ + Sbjct: 17 RELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVH 76 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 128 +D G P+H+A G + + +L+ GAD N D P+H A +G V L Sbjct: 77 ARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ 136 Query: 129 E-SDLHRRDARGLTPLELA 146 +D + R+ G + L+LA Sbjct: 137 HGADPNIRNTDGKSALDLA 155 Score = 116 bits (290), Expect = 6e-27, Method: Composition-based stats. Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 8/154 (5%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVH---PDALNRFGKTALQVMMFGSTAIALELLKQGA 65 G L AA D+ +V++ L E+++ P + A+ + + LL++GA Sbjct: 323 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGA 382 Query: 66 SPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSF 125 + N ++ +P+H AA D ++VL +HGA +N D G +H A GH Sbjct: 383 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRL 442 Query: 126 LA-AESDLHRRDARGLTPLELALQRGAQDLVDIL 158 L SD +G T A Q G + + IL Sbjct: 443 LLSYGSDPSIISLQGFT----AAQMGNEAVQQIL 472 Score = 114 bits (285), Expect = 2e-26, Method: Composition-based stats. Identities = 50/205 (24%), Positives = 71/205 (34%), Gaps = 57/205 (27%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVM-MFGSTAIALELLKQGASPNVQDTS 73 AA G V LL + A + G L FG + LL QGA PN +D Sbjct: 56 AAGFGRKDVVEHLLQMG-ANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNW 114 Query: 74 GTSPVHDAARTGFLDTLKVLVEHG----------------ADVNVP-------------- 103 +P+H+AA G +D VL++HG AD + Sbjct: 115 NYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLE 174 Query: 104 ------------------------DGTGALPIHLAVQEGHTAVVSFLAAE-SDLHRRDAR 138 DG + P+HLA +V L +D+H +D Sbjct: 175 AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG 234 Query: 139 GLTPLELALQRGAQDLVDILQGHMV 163 GL PL A G ++ ++L H Sbjct: 235 GLVPLHNACSYGHYEVTELLLKHGA 259 Score = 113 bits (284), Expect = 3e-26, Method: Composition-based stats. Identities = 45/210 (21%), Positives = 74/210 (35%), Gaps = 57/210 (27%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELLKQGA----- 65 L A + G EV LL + P+A + + T L + G + + LL+ GA Sbjct: 86 LHNACSFGH-AEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIR 144 Query: 66 -----------------------------------------------SPNVQDTSG--TS 76 + N + G ++ Sbjct: 145 NTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKST 204 Query: 77 PVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESD-LHRR 135 P+H AA + +++L++HGADV+ D G +P+H A GH V L ++ Sbjct: 205 PLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAM 264 Query: 136 DARGLTPLELALQRGAQDLVDILQGHMVAP 165 D TPL A + ++ +L H P Sbjct: 265 DLWQFTPLHEAASKNRVEVCSLLLSHGADP 294 Score = 69.2 bits (168), Expect = 7e-13, Method: Composition-based stats. Identities = 35/178 (19%), Positives = 64/178 (35%), Gaps = 27/178 (15%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELLKQGASPNVQ 70 L A + G + V LL + +A++ + T L + LL GA P + Sbjct: 239 LHNACSYGHYE-VTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLV 297 Query: 71 DTSG-------TSP--------------VHDAARTGFLDTLKVLVEHGADVNVPDGTGAL 109 + G +P + AAR L +K + + Sbjct: 298 NCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHET 357 Query: 110 PIHLAVQEGH---TAVVSFLA-AESDLHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 +H AV H V L ++++ ++ +TPL +A +R D++++L H Sbjct: 358 ALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGA 415 >5HKP-A nrPDB Length = 351 Score = 127 bits (320), Expect = 2e-30, Method: Composition-based stats. Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 2/139 (1%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPN 68 D L AA G+ +++ LL V+ A + T L + + I LL+ GA + Sbjct: 26 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 85 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 128 +D G P+H+A G + ++L++HGA VN D P+H A + V S L + Sbjct: 86 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 145 Query: 129 E-SDLHRRDARGLTPLELA 146 +D + G + +++A Sbjct: 146 HGADPTLVNCHGKSAVDMA 164 Score = 117 bits (294), Expect = 2e-27, Method: Composition-based stats. Identities = 43/154 (27%), Positives = 69/154 (44%), Gaps = 8/154 (5%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVH---PDALNRFGKTALQVMMFGSTAIALELLKQGA 65 G L AA D+ +V++ L E+++ P + A+ + +A LL++GA Sbjct: 179 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGA 238 Query: 66 SPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSF 125 + N ++ +P+H AA D ++VL +HGA +N D G +H A GH Sbjct: 239 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRL 298 Query: 126 LA-AESDLHRRDARGLTPLELALQRGAQDLVDIL 158 L SD +G T A Q G + + IL Sbjct: 299 LLSYGSDPSIISLQGFT----AAQMGNEAVQQIL 328 Score = 73.1 bits (178), Expect = 6e-14, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Query: 78 VHDAARTGFLDTLKVLV-EHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLHRR 135 + +AAR+G + L L+ + + DG + P+HLA +V L +D+H + Sbjct: 28 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 87 Query: 136 DARGLTPLELALQRGAQDLVDILQGHMV 163 D GL PL A G ++ ++L H Sbjct: 88 DKGGLVPLHNACSYGHYEVTELLLKHGA 115 Score = 69.6 bits (169), Expect = 5e-13, Method: Composition-based stats. Identities = 35/178 (19%), Positives = 64/178 (35%), Gaps = 27/178 (15%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELLKQGASPNVQ 70 L A + G + V LL + +A++ + T L + LL GA P + Sbjct: 95 LHNACSYGHYE-VTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLV 153 Query: 71 DTSG-------TSP--------------VHDAARTGFLDTLKVLVEHGADVNVPDGTGAL 109 + G +P + AAR L +K + + Sbjct: 154 NCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHET 213 Query: 110 PIHLAVQEGH---TAVVSFLA-AESDLHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 +H AV H V L ++++ ++ +TPL +A +R D++++L H Sbjct: 214 ALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGA 271 >4NIK-A nrPDB Length = 230 Score = 125 bits (313), Expect = 1e-29, Method: Composition-based stats. Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 2/151 (1%) Query: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTALQVM-MFGSTAIALELLKQGASPNVQDTSG 74 A G ++E++ + + ++ +TAL G T I LL+ G N +D +G Sbjct: 18 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 77 Query: 75 TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAV-VSFLAAESDLH 133 SP+H AA G + +K L+ GA VN + G P+H A + + V L ++ Sbjct: 78 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 137 Query: 134 RRDARGLTPLELALQRGAQDLVDILQGHMVA 164 +D T + A +G ++ IL + + Sbjct: 138 AKDHYEATAMHRAAAKGNLKMIHILLYYKAS 168 Score = 115 bits (289), Expect = 7e-27, Method: Composition-based stats. Identities = 38/152 (25%), Positives = 66/152 (43%), Gaps = 3/152 (1%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTS 73 A + G + V LL V + + G + L + G I LL +GA N + + Sbjct: 51 ACSAGHTEIVEFLLQLG-VPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN 109 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA-AESDL 132 G +P+H AA + +L+E GA+ + D A +H A +G+ ++ L ++ Sbjct: 110 GCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAST 169 Query: 133 HRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 + +D G TPL LA + +L + Sbjct: 170 NIQDTEGNTPLHLACDEERVEEAKLLVSQGAS 201 Score = 88.5 bits (218), Expect = 1e-18, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 45/112 (40%), Gaps = 1/112 (0%) Query: 55 AIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLA 114 + +L + D + +H A G + ++ L++ G VN D G P+H+A Sbjct: 25 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 84 Query: 115 VQEGHTAVVS-FLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAP 165 G +V L + ++ + G TPL A + ++ +L P Sbjct: 85 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 136 Score = 78.5 bits (192), Expect = 1e-15, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 1/100 (1%) Query: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELLKQGASPNVQDTSG 74 AA + E+ +L +PDA + + TA+ G+ + LL AS N+QDT G Sbjct: 117 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 176 Query: 75 TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLA 114 +P+H A ++ K+LV GA + + + P+ +A Sbjct: 177 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 216 >5ET1-A nrPDB Length = 353 Score = 123 bits (310), Expect = 3e-29, Method: Composition-based stats. Identities = 52/143 (36%), Positives = 71/143 (49%), Gaps = 5/143 (3%) Query: 14 GAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQG-ASPNVQD 71 AAA G + ++ LL + + G T L + FG + LL QG A+ + Sbjct: 77 DAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITT 136 Query: 72 TSGTSPVHDAARTGFLDTLKVLVEHGAD-VNVPDGTGALPIHLAVQEGHTAVVSFLAAE- 129 +G P+H AA G L +LK+LV H + VN GA P++LA QEGH V +L E Sbjct: 137 DTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQEC 196 Query: 130 -SDLHRRDARGLTPLELALQRGA 151 +D H R G+TPL A Q G Sbjct: 197 SADPHLRAQDGMTPLHAAAQMGH 219 Score = 98.9 bits (245), Expect = 8e-22, Method: Composition-based stats. Identities = 46/148 (31%), Positives = 70/148 (47%), Gaps = 5/148 (3%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQ-GASPNVQDT 72 AAA+GD+ ++ L+ +A G T L + G + L+++ A P+++ Sbjct: 146 AAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQ 205 Query: 73 SGTSPVHDAARTGFLDTLKVLVEHGADVN--VPDGTGALPIHLAVQEGHTAVVSFLAAES 130 G +P+H AA+ G L LV ADV+ D GA +H A GHT V+S+L Sbjct: 206 DGMTPLHAAAQMGHNPVLVWLV-SFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHG 264 Query: 131 DLHRRDARGLTPLELALQRGAQDLVDIL 158 +D G TPL A + G + IL Sbjct: 265 AEISQDLWGGTPLHDAAENGELECCQIL 292 Score = 98.1 bits (243), Expect = 2e-21, Method: Composition-based stats. Identities = 40/152 (26%), Positives = 60/152 (39%), Gaps = 6/152 (3%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNV- 69 L A G ++ + L+ P + G T L G + + L+ A + Sbjct: 177 LYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSF-ADVSFS 235 Query: 70 -QDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 128 QD G + +H AA G L L+ HGA+++ D G P+H A + G LA Sbjct: 236 EQDHDGATAMHFAASRGHTKVLSWLLLHGAEIS-QDLWGGTPLHDAAENGELECCQILAV 294 Query: 129 -ESDLHRRDARGLTPLELALQRGAQDLVDILQ 159 + L RD G T +LA G L+ Sbjct: 295 NGAGLDVRDHDGYTAADLAEFNGHTHCSRYLR 326 Score = 88.9 bits (219), Expect = 9e-19, Method: Composition-based stats. Identities = 45/155 (29%), Positives = 67/155 (43%), Gaps = 5/155 (3%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELL-KQGASPNVQDT 72 AA G + +R L+ + + R G T G + LL + G +D Sbjct: 44 AARSGKLHCLRYLVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDN 103 Query: 73 SGTSPVHDAARTGFLDTLKVLV-EHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-- 129 SG + +H AAR G D +K L+ + GA+ + TGALPIH A +G + L Sbjct: 104 SGATVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYP 163 Query: 130 SDLHRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 ++ + G TPL LA Q G ++ L A Sbjct: 164 EGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSA 198 Score = 87.3 bits (215), Expect = 3e-18, Method: Composition-based stats. Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 5/154 (3%) Query: 13 SGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASPNV-Q 70 AA RGD+ +R L L+ P + + G L+++ A P V + Sbjct: 8 LQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVSR 67 Query: 71 DTSGTSPVHDAARTGFLDTLKVLV-EHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA- 128 +G +P HDAA TG+L L+ L+ + G V D +GA +HLA + GH VV +L Sbjct: 68 ARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQ 127 Query: 129 -ESDLHRRDARGLTPLELALQRGAQDLVDILQGH 161 ++ G P+ A +G + +L GH Sbjct: 128 GGANSAITTDTGALPIHYAAAKGDLPSLKLLVGH 161 Score = 26.8 bits (58), Expect = 5.0, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 19/54 (35%), Gaps = 2/54 (3%) Query: 114 AVQEGHTAVVSFLAAES--DLHRRDARGLTPLELALQRGAQDLVDILQGHMVAP 165 A + G V+ L A RD+ P+ A + G + L + P Sbjct: 10 AARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALP 63 >2DWZ-A nrPDB Length = 231 Score = 121 bits (305), Expect = 1e-28, Method: Composition-based stats. Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 2/151 (1%) Query: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTALQVM-MFGSTAIALELLKQGASPNVQDTSG 74 A G + E++ + + ++ +TAL G T I LL+ G N +D +G Sbjct: 14 AYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73 Query: 75 TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAV-VSFLAAESDLH 133 SP+H AA G + +K L+ GA VN + G P+H A + + V L ++ Sbjct: 74 WSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133 Query: 134 RRDARGLTPLELALQRGAQDLVDILQGHMVA 164 +D T + A +G +V IL + + Sbjct: 134 AKDHYDATAMHRAAAKGNLKMVHILLFYKAS 164 Score = 115 bits (287), Expect = 1e-26, Method: Composition-based stats. Identities = 39/152 (25%), Positives = 65/152 (42%), Gaps = 3/152 (1%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTS 73 A + G + V LL V + + G + L + G I LL +GA N + + Sbjct: 47 ACSAGHTEIVEFLLQLG-VPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQN 105 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA-AESDL 132 G +P+H AA + +L+E GA+ + D A +H A +G+ +V L ++ Sbjct: 106 GCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKAST 165 Query: 133 HRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 + +D G TPL LA + L + Sbjct: 166 NIQDTEGNTPLHLACDEERVEEAKFLVTQGAS 197 Score = 89.6 bits (221), Expect = 6e-19, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 45/113 (39%), Gaps = 1/113 (0%) Query: 54 TAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHL 113 + +L + D + +H A G + ++ L++ G VN D G P+H+ Sbjct: 20 DELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHI 79 Query: 114 AVQEGHTAVVS-FLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAP 165 A G +V L + ++ + G TPL A + ++ +L P Sbjct: 80 AASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132 Score = 78.5 bits (192), Expect = 1e-15, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Query: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELLKQGASPNVQDTSG 74 AA + E+ +L +PDA + + TA+ G+ + LL AS N+QDT G Sbjct: 113 AASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEG 172 Query: 75 TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLA 114 +P+H A ++ K LV GA + + + P+ +A Sbjct: 173 NTPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVA 212 >3B7B-A nrPDB Length = 237 Score = 120 bits (302), Expect = 2e-28, Method: Composition-based stats. Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 3/125 (2%) Query: 43 KTALQVMM-FGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVN 101 ++ L G I L++ GA+ + +P+ +AA L+ +K L++ GA V+ Sbjct: 12 RSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVD 71 Query: 102 VPDGTGALPIHLAVQEGHTAVVSFLAAES--DLHRRDARGLTPLELALQRGAQDLVDILQ 159 D G+ +HLA ++GH VV +L + D++ +D G TP+ A + DLV +L Sbjct: 72 PKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLL 131 Query: 160 GHMVA 164 Sbjct: 132 SKGSD 136 Score = 115 bits (288), Expect = 1e-26, Method: Composition-based stats. Identities = 41/151 (27%), Positives = 67/151 (44%), Gaps = 4/151 (2%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGA-SPNV 69 L AA ++ V+ L+ + D + G T L + G + LL G N Sbjct: 48 LMEAAENNHLEAVKYLIKAGAL-VDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNC 106 Query: 70 QDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FLAA 128 QD G +P+ A +D +K+L+ G+D+N+ D + +H A G + LAA Sbjct: 107 QDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAA 166 Query: 129 ESDLHRRDARGLTPLELALQRGAQDLVDILQ 159 + DLH + G +PL +A + D V + Sbjct: 167 KCDLHAVNIHGDSPLHIAARENRYDCVVLFL 197 Score = 112 bits (280), Expect = 9e-26, Method: Composition-based stats. Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTS 73 AA +G + V+ LL + + + G T + + + LL +G+ N++D Sbjct: 84 AAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNE 143 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FLAAESDL 132 +H AA +G +D ++L+ D++ + G P+H+A +E V FL+ +SD+ Sbjct: 144 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDV 203 Query: 133 HRRDARGLTPLELALQRGAQD 153 ++ G TPL+ A Sbjct: 204 TLKNKEGETPLQCASLNSQVW 224 Score = 102 bits (254), Expect = 7e-23, Method: Composition-based stats. Identities = 39/152 (25%), Positives = 66/152 (43%), Gaps = 3/152 (1%) Query: 13 SGAAARGDVQEVRRLLHRELVHPDALNRFGKTAL-QVMMFGSTAIALELLKQGASPNVQD 71 AAA ++ +L + + D + +T L + L+K GA + +D Sbjct: 15 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 74 Query: 72 TSGTSPVHDAARTGFLDTLKVLVEHG-ADVNVPDGTGALPIHLAVQEGHTAVVSFLA-AE 129 G++ +H AA+ G + ++ L+ +G DVN D G P+ A + H +V L Sbjct: 75 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 134 Query: 130 SDLHRRDARGLTPLELALQRGAQDLVDILQGH 161 SD++ RD L A G D+ +IL Sbjct: 135 SDINIRDNEENICLHWAAFSGCVDIAEILLAA 166 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 21/60 (35%), Gaps = 1/60 (1%) Query: 105 GTGALPIHLAVQEGHTAVVSFLA-AESDLHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 P+H A + GH + L A +++ TPL A + + V L Sbjct: 9 QNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGA 68 Score = 30.7 bits (68), Expect = 0.32, Method: Composition-based stats. Identities = 6/35 (17%), Positives = 11/35 (31%) Query: 129 ESDLHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 + +PL A + G D+ +L Sbjct: 1 HMNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGA 35 >3ZKJ-A nrPDB Length = 261 Score = 115 bits (288), Expect = 9e-27, Method: Composition-based stats. Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 1/122 (0%) Query: 43 KTALQ-VMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVN 101 + + + G L+ QG + N+ SP+H+A G L +K+L++HGA VN Sbjct: 4 WSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVN 63 Query: 102 VPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGH 161 P+ A G V+ L + ++ +P+ A +RG + V+ L + Sbjct: 64 GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVNSLIAY 123 Query: 162 MV 163 Sbjct: 124 GG 125 Score = 87.7 bits (216), Expect = 2e-18, Method: Composition-based stats. Identities = 40/153 (26%), Positives = 64/153 (41%), Gaps = 4/153 (2%) Query: 14 GAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFG-STAIALELLKQGASPNVQDT 72 AA G +R L+ + + + + L G + LLK GA N Sbjct: 9 EAAIHGHQLSLRNLISQGWA-VNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTA 67 Query: 73 SGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVV-SFLAAESD 131 +P+ +A +G D + +L++HGA V P+ A PIH A + GH V S +A + Sbjct: 68 DWHTPLFNACVSGSWDCVNLLLQHGASV-QPESDLASPIHEAARRGHVECVNSLIAYGGN 126 Query: 132 LHRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 + + + TPL LA + + V L Sbjct: 127 IDHKISHLGTPLYLACENQQRACVKKLLESGAD 159 Score = 81.9 bits (201), Expect = 1e-16, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 3/154 (1%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQD 71 L A G + V+ LL + + GS LL+ GAS + Sbjct: 40 LHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASV-QPE 98 Query: 72 TSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVV-SFLAAES 130 + SP+H+AAR G ++ + L+ +G +++ P++LA + A V L + + Sbjct: 99 SDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGA 158 Query: 131 DLHRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 D++ + +PL + +++L +L Sbjct: 159 DVN-QGKGQDSPLHAVARTASEELACLLMDFGAD 191 Score = 56.9 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 3/101 (2%) Query: 14 GAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALE-LLKQGASPNVQDT 72 AA RG V+ V L+ + D T L + ++ LL+ GA N Q Sbjct: 107 EAARRGHVECVNSLIAYGG-NIDHKISHLGTPLYLACENQQRACVKKLLESGADVN-QGK 164 Query: 73 SGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHL 113 SP+H ART + +L++ GAD + G P+ L Sbjct: 165 GQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVEL 205 >2A5E-A nrPDB Length = 156 Score = 115 bits (287), Expect = 1e-26, Method: Composition-based stats. Identities = 60/125 (48%), Positives = 77/125 (61%), Gaps = 2/125 (1%) Query: 8 AGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASP 67 + D L+ AAARG V+EVR LL + P+A N +G+ +QVMM GS +A LL GA P Sbjct: 12 SADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARVAELLLLHGAEP 70 Query: 68 NVQDTSGTS-PVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 N D + + PVHDAAR GFLDTL VL GA ++V D G LP+ LA + GH V +L Sbjct: 71 NCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 Query: 127 AAESD 131 A + Sbjct: 131 RAAAG 135 Score = 68.1 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 3/118 (2%) Query: 48 VMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTG 107 G LL+ GA PN ++ G P+ G ++L+ HGA+ N D Sbjct: 19 AAARGRVEEVRALLEAGALPNAPNSYGRRPIQV-MMMGSARVAELLLLHGAEPNCADPAT 77 Query: 108 AL-PIHLAVQEGHTAVVSFL-AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 P+H A +EG + L A + L RDA G P++LA + G +D+ L+ Sbjct: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAG 135 >1D9S-A nrPDB Length = 136 Score = 112 bits (280), Expect = 7e-26, Method: Composition-based stats. Identities = 60/121 (49%), Positives = 77/121 (63%), Gaps = 2/121 (1%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQD 71 L+ AAARG V+ VR+LL P+ALNRFG+ +QVMM GS +A LL GA PN D Sbjct: 16 LATAAARGQVETVRQLLEAG-ADPNALNRFGRRPIQVMMMGSAQVAELLLLHGAEPNCAD 74 Query: 72 TSGTS-PVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAES 130 + + PVHDAAR GFLDTL VL GA ++V D G LP+ LA ++GH + +L A + Sbjct: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIARYLHAAT 134 Query: 131 D 131 Sbjct: 135 G 135 Score = 69.2 bits (168), Expect = 9e-13, Method: Composition-based stats. Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 3/119 (2%) Query: 48 VMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTG 107 G +LL+ GA PN + G P+ G ++L+ HGA+ N D Sbjct: 19 AAARGQVETVRQLLEAGADPNALNRFGRRPIQV-MMMGSAQVAELLLLHGAEPNCADPAT 77 Query: 108 AL-PIHLAVQEGHTAVVSFL-AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 P+H A +EG + L A + L DA G P++LA ++G +D+ L Sbjct: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIARYLHAATGD 136 >1WG0-A nrPDB Length = 243 Score = 109 bits (272), Expect = 6e-25, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 69/173 (39%), Gaps = 8/173 (4%) Query: 1 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDA---LNRFGKTALQVM-MFGSTAI 56 +LL++ + G + E+ L ++ + + + G T + G+ + Sbjct: 28 LLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEV 87 Query: 57 ALELLKQ--GASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLA 114 L + N G + +H A + + + L+E+GA V + D +P+H A Sbjct: 88 VKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRA 147 Query: 115 VQEGHTAVVSFL--AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAP 165 G ++ L +S ++ +D +G TPL AL G D +L A Sbjct: 148 ASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAE 200 Score = 83.8 bits (206), Expect = 3e-17, Method: Composition-based stats. Identities = 41/162 (25%), Positives = 68/162 (41%), Gaps = 7/162 (4%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELLKQGASPNVQ 70 L A + +V+ LLH + ++ G+ L + F + I LL + + N+ Sbjct: 6 LHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLD 65 Query: 71 D---TSGTSPVHDAARTGFLDTLKVLV--EHGADVNVPDGTGALPIHLAVQEGHTAVVSF 125 D SG +P H A G L+ +K L D+N G +HLAV + V F Sbjct: 66 DYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQF 125 Query: 126 LAA-ESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL 166 L + + +D PL A G+ L+++L G + + Sbjct: 126 LIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAV 167 Score = 56.1 bits (134), Expect = 7e-09, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 5/94 (5%) Query: 77 PVHDAARTGFLDTLKVLVEHGADVNVP-DGTGALPIHLAVQEGHTAVVSFLAAES-DLHR 134 P+H A ++ L+ + + D G +P+H +V + SFL ++ +++ Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64 Query: 135 ---RDARGLTPLELALQRGAQDLVDILQGHMVAP 165 D G TP +A G ++V L + P Sbjct: 65 DDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKP 98 >6AUN-A nrPDB Length = 752 Score = 108 bits (270), Expect = 1e-24, Method: Composition-based stats. Identities = 41/166 (24%), Positives = 70/166 (42%), Gaps = 11/166 (6%) Query: 4 EEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQ 63 EE L A +GD + + L+ D + G+TA + G + L+LL + Sbjct: 150 EEGCTPLHL--ACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGK 207 Query: 64 GAS--PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTA 121 AS N + G +P+H A + G + ++VL+ A NV +G PIH A++ Sbjct: 208 NASAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGF-PIHTAMKFSQKG 266 Query: 122 VVSFLAA--ESDLHRRD-ARGLTPLELALQRGAQDLVDILQGHMVA 164 + + S +H +D G +PL A ++ +L Sbjct: 267 CAEMIISMDSSQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCD 309 Score = 100 bits (250), Expect = 2e-22, Method: Composition-based stats. Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHG-ADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 + ++ G +P+H A R G + L LV++ A ++V D G H AVQ ++ V+ L Sbjct: 146 STENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLL 205 Query: 127 AAE--SDLHRRDARGLTPLELALQRGAQDLVDILQ 159 + L++ + +GLTPL LA Q G Q++V +L Sbjct: 206 GKNASAGLNQVNKQGLTPLHLACQMGKQEMVRVLL 240 Score = 81.5 bits (200), Expect = 1e-16, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 3/108 (2%) Query: 40 RFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD 99 R+G + L + +A LLK+G + +G + +H A D + VL+ +GA+ Sbjct: 285 RYGASPLHWAK--NAEMARMLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGAN 342 Query: 100 VNVPDGTGALPIHLAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELA 146 P G P+HLA+ + + ++ L +++ + G TP +A Sbjct: 343 AGTPGEHGNTPLHLAISKDNMEMIKALIVFGAEVDTPNDFGETPAFMA 390 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 28/90 (31%), Gaps = 10/90 (11%) Query: 1 MLLEEVRAGDR--------LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFG 52 MLL+ D L A R V LL + G T L + + Sbjct: 302 MLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYG-ANAGTPGEHGNTPLHLAISK 360 Query: 53 ST-AIALELLKQGASPNVQDTSGTSPVHDA 81 + L+ GA + + G +P A Sbjct: 361 DNMEMIKALIVFGAEVDTPNDFGETPAFMA 390 Score = 34.2 bits (77), Expect = 0.029, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 5/87 (5%) Query: 83 RTGFLDTLKV-LVEHGADVNVPDGTGALPIHLAVQEGHTAVV--SFLAAESDLHRRDARG 139 + L V +++H +D+ + HLAV+ G S + + ++ + G Sbjct: 95 YESSVQVLHVEVLQHLSDL-IRSHPSWTVTHLAVELGIRECFHHSRIISCANSTE-NEEG 152 Query: 140 LTPLELALQRGAQDLVDILQGHMVAPL 166 TPL LA ++G +++ L + A + Sbjct: 153 CTPLHLACRKGDSEILVELVQYCHAQM 179 >3EU9-A nrPDB Length = 240 Score = 106 bits (264), Expect = 6e-24, Method: Composition-based stats. Identities = 34/153 (22%), Positives = 59/153 (38%), Gaps = 4/153 (2%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTS 73 AA + V+ + + + T L G ++ ++L+K GA P++ D Sbjct: 49 AAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGE 108 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGH-TAVVSFLAA-ESD 131 G S +H AA+ G + L+ G DV++ D G P+ A H L Sbjct: 109 GCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVS 168 Query: 132 LHRRDA-RGLTPLELALQRGAQDLVDILQGHMV 163 ++ D T L A+ G ++ +L Sbjct: 169 VNLGDKYHKNTALHWAVLAGNTTVISLLLEAGA 201 Score = 105 bits (261), Expect = 1e-23, Method: Composition-based stats. Identities = 40/154 (25%), Positives = 76/154 (49%), Gaps = 5/154 (3%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTS 73 A +G + V +L+ P ++ G + + + FG T+I L+ +G ++ D + Sbjct: 83 ATRQGHLSMVVQLMKYG-ADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQN 141 Query: 74 GTSPVHDAARTGF-LDTLKVLVEHGADVNVPDGTG-ALPIHLAVQEGHTAVVSFLA-AES 130 G +P+ AA +D ++L+ VN+ D +H AV G+T V+S L A + Sbjct: 142 GMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGA 201 Query: 131 DLHRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 ++ ++ +G + L+LA QR +++ LQ A Sbjct: 202 NVDAQNIKGESALDLAKQRKNVWMINHLQEARQA 235 Score = 93.9 bits (232), Expect = 3e-20, Method: Composition-based stats. Identities = 39/157 (24%), Positives = 61/157 (38%), Gaps = 36/157 (22%) Query: 39 NRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTS---------------------- 76 + ++ +G EL++ G D + Sbjct: 7 DYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGA 66 Query: 77 ------------PVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS 124 P+H A R G L + L+++GAD ++ DG G IHLA Q GHT++V+ Sbjct: 67 IVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVA 126 Query: 125 FLAAES-DLHRRDARGLTPLELALQRGA-QDLVDILQ 159 +L A+ D+ D G+TPL A R D +L Sbjct: 127 YLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLL 163 Score = 59.6 bits (143), Expect = 7e-10, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 36/87 (41%), Gaps = 2/87 (2%) Query: 81 AARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSF-LAAESDLHRRDAR- 138 A + G + + LVE G DV PD +H A +V + ++ + + + Sbjct: 16 ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDL 75 Query: 139 GLTPLELALQRGAQDLVDILQGHMVAP 165 TPL A ++G +V L + P Sbjct: 76 NSTPLHWATRQGHLSMVVQLMKYGADP 102 >5D68-A nrPDB Length = 486 Score = 103 bits (257), Expect = 4e-23, Method: Composition-based stats. Identities = 31/128 (24%), Positives = 58/128 (45%), Gaps = 7/128 (5%) Query: 45 ALQ-VMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHG-ADVNV 102 L G + + LL + S N D+ +P+H A G ++ ++L+E G + N+ Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100 Query: 103 PDGTGALPIHLAVQEGHTAVVSFLAAE--SDLHRRDARGLTPLELALQRGA---QDLVDI 157 +G + P+H A GH +V L +D H D +G +PL + + ++ + Sbjct: 101 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 160 Query: 158 LQGHMVAP 165 L+ + P Sbjct: 161 LKEAINKP 168 Score = 48.8 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 33/84 (39%), Gaps = 5/84 (5%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGA-SPNVQDT 72 A G V+ R LL + +P+ LN + L G I LL ++ D Sbjct: 78 ACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQ 137 Query: 73 SGTSPVHDA---ARTGFLDTLKVL 93 G SP++ + + + K+L Sbjct: 138 QGRSPLNICEENKQNNWEEAAKLL 161 >3T9K-A nrPDB Length = 390 Score = 99.6 bits (247), Expect = 5e-22, Method: Composition-based stats. Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 15/134 (11%) Query: 27 LLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGF 86 LL R HP +L T + G+ + + A +P+ A Sbjct: 202 LLFRASGHPPSL----PTMADALAHGADVNWVNGGQDNA----------TPLIQATAANS 247 Query: 87 LDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-FLAAESDLHRRDARGLTPLEL 145 L + L+++GA+VN D G P+H A GHT + FL +DL RD+ G PL + Sbjct: 248 LLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTI 307 Query: 146 ALQRGAQDLVDILQ 159 A++ D+V +L+ Sbjct: 308 AMETANADIVTLLR 321 Score = 48.8 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 29/74 (39%), Gaps = 3/74 (4%) Query: 94 VEHGADVNVPDG--TGALPIHLAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQRG 150 + HGADVN +G A P+ A FL +++++ D+ G PL A G Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279 Query: 151 AQDLVDILQGHMVA 164 L + Sbjct: 280 HTGLACLFLKRGAD 293 >6E2G-A nrPDB Length = 727 Score = 96.9 bits (240), Expect = 4e-21, Method: Composition-based stats. Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 25/144 (17%) Query: 42 GKTALQVMMFGSTA-IALELLKQGASPNVQDTS-------------GTSPVHDAARTGFL 87 G+TAL + + + LL +GAS + + T G P+ AA G Sbjct: 117 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 176 Query: 88 DTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-----FLAAESDLHRR------D 136 + +++L+EHGAD+ D G +H+ + + + L+ + H + + Sbjct: 177 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPN 236 Query: 137 ARGLTPLELALQRGAQDLVDILQG 160 +GLTP +LA G + L Sbjct: 237 NQGLTPFKLAGVEGNIVMFQHLMQ 260 Score = 61.5 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 52/142 (36%), Gaps = 21/142 (14%) Query: 44 TALQVMMFGSTAIALE-LLK-QGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD-- 99 + L + + AL LLK +G + + G + +H AA L+ VL+E + Sbjct: 47 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 106 Query: 100 ---VNVPDGTGALPIHLAVQEGHTAVVSFLAAESD--------------LHRRDARGLTP 142 + G +H+AV + +V L A H G P Sbjct: 107 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 166 Query: 143 LELALQRGAQDLVDILQGHMVA 164 L A G++++V +L H Sbjct: 167 LSFAACVGSEEIVRLLIEHGAD 188 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 25/62 (40%), Gaps = 2/62 (3%) Query: 102 VPDGTGALPIHLAVQEGHTA-VVSFLAAES-DLHRRDARGLTPLELALQRGAQDLVDILQ 159 P+ LA +E + ++ L E ++H++ A G T L +A + +L Sbjct: 40 QQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLM 99 Query: 160 GH 161 Sbjct: 100 EA 101 Score = 34.5 bits (78), Expect = 0.021, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 36/98 (36%), Gaps = 12/98 (12%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGST-----AIALELLKQG 64 LS AA G +E+ RLL A + G T L +++ + LL Sbjct: 165 HPLSFAACVG-SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223 Query: 65 ASPNVQ------DTSGTSPVHDAARTGFLDTLKVLVEH 96 +++ + G +P A G + + L++ Sbjct: 224 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK 261 >5UQE-A nrPDB Length = 520 Score = 93.1 bits (230), Expect = 5e-20, Method: Composition-based stats. Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 2/88 (2%) Query: 78 VHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA--AESDLHRR 135 + AA TG + L+ D+ D +H+A EGH VV FL + + + Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 480 Query: 136 DARGLTPLELALQRGAQDLVDILQGHMV 163 D TP++ AL G D+ ILQ + V Sbjct: 481 DRWNNTPMDEALHFGHHDVFKILQEYQV 508 Score = 54.6 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 3/95 (3%) Query: 4 EEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLK 62 + V++ L AA GDV +RR + + + +TAL V G + LL+ Sbjct: 413 QRVKSVINLLFAAYTGDVSALRRF-ALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE 471 Query: 63 -QGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEH 96 +P +D +P+ +A G D K+L E+ Sbjct: 472 ACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEY 506 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 28/82 (34%), Gaps = 1/82 (1%) Query: 46 LQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHG-ADVNVPD 104 L G + +D + +H AA G ++ +K L+E + D Sbjct: 422 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 481 Query: 105 GTGALPIHLAVQEGHTAVVSFL 126 P+ A+ GH V L Sbjct: 482 RWNNTPMDEALHFGHHDVFKIL 503 >6DMR-A nrPDB Length = 730 Score = 90.4 bits (223), Expect = 3e-19, Method: Composition-based stats. Identities = 36/146 (24%), Positives = 61/146 (41%), Gaps = 28/146 (19%) Query: 42 GKTALQVMMFGSTA-IALELLKQGASPNVQDTS-------------GTSPVHDAARTGFL 87 G+TAL + + + LL +GAS + + T G P+ AA G Sbjct: 117 GQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSE 176 Query: 88 DTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS----FLAA---ESDLHRR----- 135 + +++L+EHGAD+ D G +H+ + + + L + SD H + Sbjct: 177 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSD-HLQSLELV 235 Query: 136 -DARGLTPLELALQRGAQDLVDILQG 160 + +GLTP +LA G + L Sbjct: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQ 261 Score = 53.0 bits (126), Expect = 6e-08, Method: Composition-based stats. Identities = 35/181 (19%), Positives = 64/181 (35%), Gaps = 33/181 (18%) Query: 17 ARGDVQEVRRLL------------HRELVHPDALNRFGKTALQVMMFGSTAIALELLKQG 64 A+G ++++LL +R+ V+ R + L + L++L Sbjct: 8 AKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLN 67 Query: 65 ASPNVQDTS--GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGT-----GALPIHLAVQE 117 S + Q G + +H AA L+ +L+E ++ G +H+AV Sbjct: 68 QSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMN 127 Query: 118 GHTAVVSFLAAESD--------------LHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 + +V L A H G PL A G++++V +L H Sbjct: 128 QNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGA 187 Query: 164 A 164 Sbjct: 188 D 188 >4OT9-A nrPDB Length = 359 Score = 89.2 bits (220), Expect = 7e-19, Method: Composition-based stats. Identities = 44/161 (27%), Positives = 69/161 (42%), Gaps = 12/161 (7%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF---GSTAIALELLKQGAS----- 66 A G V LL P L+R G +A+ + + G+ + LL+ GA Sbjct: 128 AVITGQTSVVSFLLRVG-ADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQL 186 Query: 67 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTG-ALPIHLAVQEGHTAVVSF 125 ++ D G PVH A R + L +LV+ GA+V + G +HLA + +V+ Sbjct: 187 LHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTH 246 Query: 126 LAAE--SDLHRRDARGLTPLELALQRGAQDLVDILQGHMVA 164 L + ++++ R G TPL LA G L +L Sbjct: 247 LVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGAD 287 Score = 74.6 bits (182), Expect = 2e-14, Method: Composition-based stats. Identities = 36/160 (22%), Positives = 63/160 (39%), Gaps = 15/160 (9%) Query: 19 GDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALEL---LKQGAS---PNVQD 71 G + R LL + A + G T L + + G T++ ++ + N+ + Sbjct: 59 GVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTN 118 Query: 72 TSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLA--VQEGHTAVVSFLAAE 129 +P+H A TG + L+ GAD + D G +HLA G ++ L Sbjct: 119 HLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQS 178 Query: 130 SDL------HRRDARGLTPLELALQRGAQDLVDILQGHMV 163 H D GL P+ LA++ + + +D+L Sbjct: 179 GAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGA 218 Score = 52.6 bits (125), Expect = 8e-08, Method: Composition-based stats. Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 16 AARGDVQEVRRLLHRELVHPDALNR-FGKTALQVMM-FGSTAIALELL-KQGASPNVQDT 72 A R E LL +A R G+TAL + + L+ K A+ N + Sbjct: 201 AVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTF 260 Query: 73 SGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPI 111 +G +P+H AA G+ ++L++ GAD++ + P+ Sbjct: 261 AGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 299 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 31/73 (42%), Gaps = 7/73 (9%) Query: 100 VNVPDGTGALPIHLAVQEGHTAVVS---FLAAESD----LHRRDARGLTPLELALQRGAQ 152 + D G P+HLA+ G T+V+ ++ + ++ + TPL LA+ G Sbjct: 75 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 134 Query: 153 DLVDILQGHMVAP 165 +V L P Sbjct: 135 SVVSFLLRVGADP 147 >5DND-A nrPDB Length = 588 Score = 88.9 bits (219), Expect = 9e-19, Method: Composition-based stats. Identities = 31/97 (31%), Positives = 51/97 (52%), Gaps = 1/97 (1%) Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 +VQD S A G L+ L+ L+E G+D+ + D G +H+A + G VV+ L Sbjct: 416 SVQDAVMPSLALALAHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLL 475 Query: 128 A-ESDLHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 D++ RD GL+PL LA+Q ++ + +L+ Sbjct: 476 HRGMDVNARDRDGLSPLLLAVQGRHRECIRLLRKAGA 512 Score = 76.9 bits (188), Expect = 4e-15, Method: Composition-based stats. Identities = 33/147 (22%), Positives = 66/147 (44%), Gaps = 4/147 (2%) Query: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASPNVQDTSG 74 A G+++ ++ L+ + G+T L V G + LL +G N +D G Sbjct: 430 AHAGELEALQALMELGS-DLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDG 488 Query: 75 TSPVHDAARTGFLDTLKVLVEHGADVNVPDGT--GALPIHLAVQEGHTAVVSFLAAESDL 132 SP+ A + + +++L + GA ++ D G LA + + ++ A +DL Sbjct: 489 LSPLLLAVQGRHRECIRLLRKAGACLSPQDLKDAGTELCRLASRADMEGLQAWGQAGADL 548 Query: 133 HRRDARGLTPLELALQRGAQDLVDILQ 159 + G + L +A G Q+++ +L+ Sbjct: 549 QQPGYDGRSALCVAEAAGNQEVLALLR 575 Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 2/121 (1%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQ-GASP 67 G L AAR V +L + +A +R G + L + + G + LL++ GA Sbjct: 455 GQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGLSPLLLAVQGRHRECIRLLRKAGACL 514 Query: 68 NVQD-TSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 + QD + + A ++ L+ + GAD+ P G + +A G+ V++ L Sbjct: 515 SPQDLKDAGTELCRLASRADMEGLQAWGQAGADLQQPGYDGRSALCVAEAAGNQEVLALL 574 Query: 127 A 127 Sbjct: 575 R 575 >2KXP-C nrPDB Length = 118 Score = 87.7 bits (216), Expect = 2e-18, Method: Composition-based stats. Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 1/98 (1%) Query: 48 VMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTG 107 + G + + +G N G P+H AA G L+ L+ L+ GAD+N PD Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHH 68 Query: 108 ALPIHLAVQEGHTAVVSFLA-AESDLHRRDARGLTPLE 144 P+ AV EGH + V L +D + GLT LE Sbjct: 69 ITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALE 106 Score = 73.1 bits (178), Expect = 5e-14, Method: Composition-based stats. Identities = 25/103 (24%), Positives = 39/103 (37%), Gaps = 2/103 (1%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASPN 68 A GD+ EV+ + + + G+ L G I LL +GA N Sbjct: 4 KEFMWALKNGDLDEVKDYVAKGE-DVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADIN 62 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPI 111 D +P+ A G + +K+L+ GAD V G + Sbjct: 63 APDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAL 105 Score = 67.3 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 1/88 (1%) Query: 78 VHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA-AESDLHRRD 136 A + G LD +K V G DVN G P+H A G ++ FL +D++ D Sbjct: 6 FMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPD 65 Query: 137 ARGLTPLELALQRGAQDLVDILQGHMVA 164 +TPL A+ G V +L Sbjct: 66 KHHITPLLSAVYEGHVSCVKLLLSKGAD 93 >5U0J-A nrPDB Length = 140 Score = 86.2 bits (212), Expect = 7e-18, Method: Composition-based stats. Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 2/88 (2%) Query: 78 VHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA--AESDLHRR 135 + AA TG + L+ D+ D +H+A EGH VV FL + + + Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 87 Query: 136 DARGLTPLELALQRGAQDLVDILQGHMV 163 D TP++ AL G D+ ILQ + V Sbjct: 88 DRWNNTPMDEALHFGHHDVFKILQEYQV 115 Score = 50.0 bits (118), Expect = 5e-07, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 28/82 (34%), Gaps = 1/82 (1%) Query: 46 LQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHG-ADVNVPD 104 L G + +D + +H AA G ++ +K L+E + D Sbjct: 29 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 88 Query: 105 GTGALPIHLAVQEGHTAVVSFL 126 P+ A+ GH V L Sbjct: 89 RWNNTPMDEALHFGHHDVFKIL 110 Score = 49.2 bits (116), Expect = 8e-07, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLK-QGASPNV 69 L AA GDV +RR + + + +TAL V G + LL+ +P Sbjct: 28 LLFAAYTGDVSALRRF-ALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFP 86 Query: 70 QDTSGTSPVHDAARTGFLDTLKVLVEH 96 +D +P+ +A G D K+L E+ Sbjct: 87 KDRWNNTPMDEALHFGHHDVFKILQEY 113 >5U0K-A nrPDB Length = 141 Score = 86.2 bits (212), Expect = 7e-18, Method: Composition-based stats. Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 2/87 (2%) Query: 78 VHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL--AAESDLHRR 135 + AA +G + L+ D+ D +H+A EGH VV FL A + + + Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAK 88 Query: 136 DARGLTPLELALQRGAQDLVDILQGHM 162 D G PL+ A+Q ++V +LQ + Sbjct: 89 DRWGNIPLDDAVQFNHLEVVKLLQDYQ 115 Score = 59.2 bits (142), Expect = 8e-10, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 32/87 (36%), Gaps = 1/87 (1%) Query: 46 LQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHG-ADVNVPD 104 L G + +D + +H AA G ++ +K L+E + D Sbjct: 30 LFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKD 89 Query: 105 GTGALPIHLAVQEGHTAVVSFLAAESD 131 G +P+ AVQ H VV L D Sbjct: 90 RWGNIPLDDAVQFNHLEVVKLLQDYQD 116 Score = 43.4 bits (101), Expect = 4e-05, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 1/50 (2%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM-FGSTAIALEL 60 L AAA G ++ V+ L+ V+P A +R+G L + F + L Sbjct: 62 LHVAAAEGHIEVVKFLIEACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLL 111 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 21/54 (38%), Gaps = 1/54 (1%) Query: 111 IHLAVQEGHTAVVS-FLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 + A G + + F + D+ ++D T L +A G ++V L Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACK 82 >6BOA-A nrPDB Length = 742 Score = 85.4 bits (210), Expect = 1e-17, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 56/145 (38%), Gaps = 26/145 (17%) Query: 42 GKTALQVMMFGST-AIALELLKQGASPNVQDTS-------------GTSPVHDAARTGFL 87 G+TAL + + + LL + AS + + T G P+ AA Sbjct: 117 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 176 Query: 88 DTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSF---LAAESDLH---------RR 135 + +++L+EHGAD+ D G +H+ + + + L D H Sbjct: 177 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVP 236 Query: 136 DARGLTPLELALQRGAQDLVDILQG 160 + +GLTP +LA G + L Sbjct: 237 NHQGLTPFKLAGVEGNTVMFQHLMQ 261 Score = 55.3 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 50/142 (35%), Gaps = 21/142 (14%) Query: 44 TALQVMMFGSTAIALELLKQGAS--PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD-- 99 + L + + AL L + + + G + +H AA L+ VL+E + Sbjct: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106 Query: 100 ---VNVPDGTGALPIHLAVQEGHTAVVS-FLAAESDLHRRDA-------------RGLTP 142 + G +H+AV + +V LA + + R G P Sbjct: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166 Query: 143 LELALQRGAQDLVDILQGHMVA 164 L A ++++V +L H Sbjct: 167 LSFAACVNSEEIVRLLIEHGAD 188 Score = 37.2 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 23/62 (37%), Gaps = 2/62 (3%) Query: 102 VPDGTGALPIHLAVQEGHTAVVSFLAAESD--LHRRDARGLTPLELALQRGAQDLVDILQ 159 P+ LA ++ ++ L D +H+R A G T L +A + +L Sbjct: 40 QQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLM 99 Query: 160 GH 161 Sbjct: 100 EA 101 Score = 33.0 bits (74), Expect = 0.069, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 35/100 (35%), Gaps = 12/100 (12%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMM--FGSTAIA----LELLK 62 G+ AA + +E+ RLL A + G T L +++ T L L Sbjct: 163 GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 222 Query: 63 QGASPNVQ------DTSGTSPVHDAARTGFLDTLKVLVEH 96 ++Q + G +P A G + L++ Sbjct: 223 DRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262 >2RFA-A nrPDB Length = 232 Score = 85.0 bits (209), Expect = 1e-17, Method: Composition-based stats. Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 25/144 (17%) Query: 42 GKTALQVMMFGSTA-IALELLKQGASPNVQDTS-------------GTSPVHDAARTGFL 87 G+TAL + + + LL +GAS + + T G P+ AA G Sbjct: 75 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 134 Query: 88 DTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-----FLAAESDLHRR------D 136 + +++L+EHGAD+ D G +H+ + + + L+ + H + + Sbjct: 135 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPN 194 Query: 137 ARGLTPLELALQRGAQDLVDILQG 160 +GLTP +LA G + L Sbjct: 195 NQGLTPFKLAGVEGNIVMFQHLMQ 218 Score = 53.4 bits (127), Expect = 4e-08, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 49/144 (34%), Gaps = 20/144 (13%) Query: 41 FGKTALQVMMFGSTAIALELLK-QGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGAD 99 + L +LLK +G + + G + +H AA L+ VL+E + Sbjct: 3 WESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 62 Query: 100 -----VNVPDGTGALPIHLAVQEGHTAVVSFLAAESD--------------LHRRDARGL 140 + G +H+AV + +V L A H G Sbjct: 63 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 122 Query: 141 TPLELALQRGAQDLVDILQGHMVA 164 PL A G++++V +L H Sbjct: 123 HPLSFAACVGSEEIVRLLIEHGAD 146 Score = 29.9 bits (66), Expect = 0.54, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 36/98 (36%), Gaps = 12/98 (12%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGST-----AIALELLKQG 64 LS AA G +E+ RLL A + G T L +++ + LL Sbjct: 123 HPLSFAACVG-SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 181 Query: 65 ASPNVQ------DTSGTSPVHDAARTGFLDTLKVLVEH 96 +++ + G +P A G + + L++ Sbjct: 182 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK 219 >3LJN-A nrPDB Length = 364 Score = 81.9 bits (201), Expect = 1e-16, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 1/88 (1%) Query: 71 DTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAES 130 D +H AAR G D ++ L+E G + + G +HLA + G +LA+ Sbjct: 17 DDENMEKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG 76 Query: 131 DLHRRDARGLTPLELALQRGAQDLVDIL 158 ++H G P+ LA+ DLV L Sbjct: 77 EVHSL-WHGQKPIHLAVMANKTDLVVAL 103 Score = 66.9 bits (162), Expect = 4e-12, Method: Composition-based stats. Identities = 45/172 (26%), Positives = 66/172 (38%), Gaps = 30/172 (17%) Query: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQVM-MFGSTAIALELLKQGASPNVQDTS 73 AA +G EVRRL+ V P NRFG TAL + FG A L G ++ Sbjct: 27 AARKGQTDEVRRLIETG-VSPTIQNRFGCTALHLACKFGCVDTAKYLASVGEVHSL--WH 83 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGAD---------VNVPDG-------------TGALPI 111 G P+H A D + LVE GA +N D G + Sbjct: 84 GQKPIHLAVMANKTDLVVALVE-GAKERGQMPESLLNECDEREVNEIGSHVKHCKGQTAL 142 Query: 112 HLAVQEG--HTAVVSFLAA-ESDLHRRDARGLTPLELALQRGAQDLVDILQG 160 H V G + ++ L + +D TPL A++ ++ +D++ Sbjct: 143 HWCVGLGPEYLEMIKILVQLGASPTAKDKADETPLMRAMEFRNREALDLMMD 194 Score = 66.1 bits (160), Expect = 7e-12, Method: Composition-based stats. Identities = 36/154 (23%), Positives = 55/154 (35%), Gaps = 31/154 (20%) Query: 39 NRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHG 97 + + V G T L++ G SP +Q+ G + +H A + G +DT K L Sbjct: 17 DDENMEKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYL---- 72 Query: 98 ADVNVPDG--TGALPIHLAVQEGHTAVVSFLAAES----------------------DLH 133 A V G PIHLAV T +V L + H Sbjct: 73 ASVGEVHSLWHGQKPIHLAVMANKTDLVVALVEGAKERGQMPESLLNECDEREVNEIGSH 132 Query: 134 RRDARGLTPLELALQRG--AQDLVDILQGHMVAP 165 + +G T L + G +++ IL +P Sbjct: 133 VKHCKGQTALHWCVGLGPEYLEMIKILVQLGASP 166 Score = 48.4 bits (114), Expect = 1e-06, Method: Composition-based stats. Identities = 34/161 (21%), Positives = 62/161 (38%), Gaps = 20/161 (12%) Query: 20 DVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGAS------PNVQDTS 73 + E+ ++L + P A ++ +T L M AL+L+ + + Sbjct: 151 EYLEMIKILVQLGASPTAKDKADETPLMRAMEFRNREALDLMMDTVPSKSSLRLDYANKQ 210 Query: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLH 133 G S +H A + D VE G DVN+ D +P++L+V+ + L ++D+ Sbjct: 211 GNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLTKELLQKTDVF 270 Query: 134 ----RRDARGLTPLEL----------ALQRGAQDLVDILQG 160 G T L A Q+++ +LQ Sbjct: 271 LIQACPYHNGTTVLPDRVVWLDFVPAAADPSKQEVLQLLQE 311 >3EHQ-A nrPDB Length = 222 Score = 75.4 bits (184), Expect = 1e-14, Method: Composition-based stats. Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 2/99 (2%) Query: 67 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 126 Q S +P+H+AA+ G L L+ +++ VN D G+ ++ A GH +V L Sbjct: 66 VAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEML 125 Query: 127 --AAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMV 163 +L++++ G T L A +G D+V +L Sbjct: 126 FTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGA 164 Score = 71.5 bits (174), Expect = 1e-13, Method: Composition-based stats. Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 6/127 (4%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFG-STAIALELLKQ-GASP 67 + L AA RG++ +R L + + L++ G TAL G I L Q Sbjct: 75 NPLHEAAKRGNLSWLRECLDNRVG-VNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIEL 133 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 N Q+ G + +H AA G+ D +++L+ GA ++ + L +A + A S L Sbjct: 134 NQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMAT---NAACASLLK 190 Query: 128 AESDLHR 134 + Sbjct: 191 KKQGTDA 197 >5AN8-A nrPDB Length = 613 Score = 68.8 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 40/170 (23%), Positives = 65/170 (38%), Gaps = 37/170 (21%) Query: 33 VHPDALNRF--GKTALQVMMFGSTAIALELL-KQGASPNVQDTS-------------GTS 76 V+ + + G +AL + + + ++LL + GA+ + + G Sbjct: 76 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 135 Query: 77 PVHDAARTGFLDTLKVLVEH---GADVNVPDGTGALPIHLAVQ------EGHTAVVS--- 124 P+ AA T D + L+E+ A + D G +H V E VV Sbjct: 136 PLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYD 195 Query: 125 -FLAAESDL-------HRRDARGLTPLELALQRGAQDLVD-ILQGHMVAP 165 L A + L + GLTPL+LA + G ++ ILQ AP Sbjct: 196 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAP 245 Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 43/174 (24%), Positives = 62/174 (35%), Gaps = 39/174 (22%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKT-----------ALQVMMFGSTAIAL 58 DRL ARG+ +++ LL L T A+ + G A Sbjct: 1 DRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQ 60 Query: 59 ELLKQGAS-------PNVQDTS----GTSPVHDAARTGFLDTLKVLVEHGADVNVPD--- 104 LL+ N Q T G S +H A L +K+LVE+GA+V+ Sbjct: 61 PLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGH 120 Query: 105 ----------GTGALPIHLAVQEGHTAVVSFLAAE----SDLHRRDARGLTPLE 144 G LP+ LA VV++L + L +D+ G T L Sbjct: 121 FFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLH 174 >3UI2-A nrPDB Length = 244 Score = 68.4 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 4/103 (3%) Query: 14 GAAARGDVQEVRRLLHRELVHPDALNRFGKTAL-QVMMFGSTAIALELLKQGASPNVQD- 71 AA + D Q + +LL DA++ G+TAL V GS L + GA + +D Sbjct: 51 TAARKADEQALSQLLEDR--DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDM 108 Query: 72 TSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLA 114 G + +H AA + ++ LVE GAD+ V D G + LA Sbjct: 109 RGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 151 Score = 63.8 bits (154), Expect = 3e-11, Method: Composition-based stats. Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 2/107 (1%) Query: 44 TALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVP 103 T + AL L + + D +G + + A G +++L E GAD++ Sbjct: 47 TPWWTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHR 106 Query: 104 DGTGA-LPIHLAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQ 148 D G +H+A VV L +D+ D RGLT LELA + Sbjct: 107 DMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELARE 153 Score = 61.1 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 3/91 (3%) Query: 76 SPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA-AESDLHR 134 +P AAR L L+E DV+ D G + G V LA A +DL Sbjct: 47 TPWWTAARKADEQALSQLLED-RDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 105 Query: 135 RD-ARGLTPLELALQRGAQDLVDILQGHMVA 164 RD GLT L +A ++V+ L Sbjct: 106 RDMRGGLTALHMAAGYVRPEVVEALVELGAD 136 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALN-RFGKTALQVMM-FGSTAIALELLKQGASPNV 69 L A G + VR LL D + R G TAL + + + L++ GA V Sbjct: 81 LLFVAGLGSDKCVR-LLAEAGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEV 139 Query: 70 QDTSGTSPVHDA 81 +D G + + A Sbjct: 140 EDERGLTALELA 151 >3DEO-A nrPDB Length = 183 Score = 67.3 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 4/103 (3%) Query: 14 GAAARGDVQEVRRLLHRELVHPDALNRFGKTAL-QVMMFGSTAIALELLKQGASPNVQD- 71 AA + D Q + +LL DA++ G+TAL V GS L + GA + +D Sbjct: 50 TAARKADEQALSQLLEDR--DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDM 107 Query: 72 TSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLA 114 G + +H AA + ++ LVE GAD+ V D G + LA Sbjct: 108 RGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 150 Score = 63.0 bits (152), Expect = 6e-11, Method: Composition-based stats. Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 2/107 (1%) Query: 44 TALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVP 103 T + AL L + + D +G + + A G +++L E GAD++ Sbjct: 46 TPWWTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHR 105 Query: 104 DGTGA-LPIHLAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQ 148 D G +H+A VV L +D+ D RGLT LELA + Sbjct: 106 DMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELARE 152 Score = 60.0 bits (144), Expect = 4e-10, Method: Composition-based stats. Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 3/91 (3%) Query: 76 SPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA-AESDLHR 134 +P AAR L L+E DV+ D G + G V LA A +DL Sbjct: 46 TPWWTAARKADEQALSQLLED-RDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 104 Query: 135 RD-ARGLTPLELALQRGAQDLVDILQGHMVA 164 RD GLT L +A ++V+ L Sbjct: 105 RDMRGGLTALHMAAGYVRPEVVEALVELGAD 135 Score = 43.4 bits (101), Expect = 4e-05, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALN-RFGKTALQVMM-FGSTAIALELLKQGASPNV 69 L A G + VR LL D + R G TAL + + + L++ GA V Sbjct: 80 LLFVAGLGSDKCVR-LLAEAGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEV 138 Query: 70 QDTSGTSPVHDA 81 +D G + + A Sbjct: 139 EDERGLTALELA 150 >5IRX-A nrPDB Length = 636 Score = 67.3 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 38/160 (23%), Positives = 60/160 (37%), Gaps = 36/160 (22%) Query: 42 GKTALQVMMFGST-AIALELLKQGASPNVQDTS--------------GTSPVHDAARTGF 86 G+TAL + + + L++ GA G P+ AA T Sbjct: 96 GQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQ 155 Query: 87 LDTLKVLVEHG---ADVNVPDGTGALPIHLAVQE-----GHTAVV-----SFLAAESDLH 133 L +K L+++ AD++ D G +H V+ +T V L + LH Sbjct: 156 LAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLH 215 Query: 134 RR-------DARGLTPLELALQRGAQDLVD-ILQGHMVAP 165 + +GLTPL LA G ++ ILQ + P Sbjct: 216 PTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIHEP 255 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 46/155 (29%), Gaps = 34/155 (21%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNR--------------FGKTALQVMM-FGS 53 G A + LL A FG+ L + Sbjct: 96 GQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQ 155 Query: 54 TAIALELLKQG---ASPNVQDTSGTSPVHDAARTGF--LDTLKVL-------VEHGADV- 100 AI LL+ A + +D+ G + +H +D K + + GA + Sbjct: 156 LAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLH 215 Query: 101 ------NVPDGTGALPIHLAVQEGHTAVVSFLAAE 129 + + G P+ LA G V++++ Sbjct: 216 PTLKLEEITNRKGLTPLALAASSGKIGVLAYILQR 250 Score = 31.5 bits (70), Expect = 0.17, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 26/75 (34%), Gaps = 15/75 (20%) Query: 105 GTGALPIHLAVQE---GHTAVVSFLAAES----------DLHRRDAR--GLTPLELALQR 149 TG + A+ G ++ L + + D+ G T L +A++R Sbjct: 47 ETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIER 106 Query: 150 GAQDLVDILQGHMVA 164 LV +L + Sbjct: 107 RNMTLVTLLVENGAD 121 >6OO7-A nrPDB Length = 786 Score = 66.9 bits (162), Expect = 4e-12, Method: Composition-based stats. Identities = 40/170 (23%), Positives = 65/170 (38%), Gaps = 37/170 (21%) Query: 33 VHPDALNRF--GKTALQVMMFGSTAIALELL-KQGASPNVQDTS-------------GTS 76 V+ + + G +AL + + + ++LL + GA+ + + G Sbjct: 151 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 210 Query: 77 PVHDAARTGFLDTLKVLVEHG---ADVNVPDGTGALPIHLAVQ------EGHTAVVS--- 124 P+ AA T D + L+E+ A + D G +H V E VV Sbjct: 211 PLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYD 270 Query: 125 -FLAAESDL-------HRRDARGLTPLELALQRGAQDLVD-ILQGHMVAP 165 L A + L + GLTPL+LA + G ++ ILQ AP Sbjct: 271 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAP 320 Score = 50.3 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 43/174 (24%), Positives = 62/174 (35%), Gaps = 39/174 (22%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKT-----------ALQVMMFGSTAIAL 58 DRL ARG+ +++ LL L T A+ + G A Sbjct: 76 DRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQ 135 Query: 59 ELLKQGAS-------PNVQDTS----GTSPVHDAARTGFLDTLKVLVEHGADVNVPD--- 104 LL+ N Q T G S +H A L +K+LVE+GA+V+ Sbjct: 136 PLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGH 195 Query: 105 ----------GTGALPIHLAVQEGHTAVVSFLAAE----SDLHRRDARGLTPLE 144 G LP+ LA VV++L + L +D+ G T L Sbjct: 196 FFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLH 249 >6BO5-A nrPDB Length = 695 Score = 65.7 bits (159), Expect = 9e-12, Method: Composition-based stats. Identities = 37/170 (21%), Positives = 64/170 (37%), Gaps = 37/170 (21%) Query: 33 VHPDALNRF--GKTALQVMMFGSTAIALELL-KQGASPNVQDTS-------------GTS 76 V+ + F G +AL + + + ++LL + GA +++ G Sbjct: 113 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 172 Query: 77 PVHDAARTGFLDTLKVLVEHG---ADVNVPDGTGALPIHLAVQ----------------E 117 P+ AA T D + L+E+ A + D G +H V + Sbjct: 173 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 232 Query: 118 GHTAVVSFLAAESDLH-RRDARGLTPLELALQRGAQDLVD-ILQGHMVAP 165 G + + L L + +GLTPL+LA + G ++ ILQ P Sbjct: 233 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGP 282 Score = 51.1 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 39/174 (22%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKT-----------ALQVMMFGSTAIAL 58 DRL +RG +E+ LL + L T A+ + G A + Sbjct: 38 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 97 Query: 59 ELLKQGAS-------PNVQDTS----GTSPVHDAARTGFLDTLKVLVEHGADVNVPD--- 104 LL+ N Q T G S +H A L +K+LVE+GADV++ Sbjct: 98 PLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 157 Query: 105 ----------GTGALPIHLAVQEGHTAVVSFLAAE----SDLHRRDARGLTPLE 144 G LP+ LA VV++L + L D+ G T L Sbjct: 158 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLH 211 >5HI9-A nrPDB Length = 770 Score = 65.7 bits (159), Expect = 9e-12, Method: Composition-based stats. Identities = 37/170 (21%), Positives = 64/170 (37%), Gaps = 37/170 (21%) Query: 33 VHPDALNRF--GKTALQVMMFGSTAIALELL-KQGASPNVQDTS-------------GTS 76 V+ + F G +AL + + + ++LL + GA +++ G Sbjct: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212 Query: 77 PVHDAARTGFLDTLKVLVEHG---ADVNVPDGTGALPIHLAVQ----------------E 117 P+ AA T D + L+E+ A + D G +H V + Sbjct: 213 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 272 Query: 118 GHTAVVSFLAAESDLH-RRDARGLTPLELALQRGAQDLVD-ILQGHMVAP 165 G + + L L + +GLTPL+LA + G ++ ILQ P Sbjct: 273 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGP 322 Score = 51.1 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 39/174 (22%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKT-----------ALQVMMFGSTAIAL 58 DRL +RG +E+ LL + L T A+ + G A + Sbjct: 78 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 137 Query: 59 ELLKQGAS-------PNVQDTS----GTSPVHDAARTGFLDTLKVLVEHGADVNVPD--- 104 LL+ N Q T G S +H A L +K+LVE+GADV++ Sbjct: 138 PLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 197 Query: 105 ----------GTGALPIHLAVQEGHTAVVSFLAAE----SDLHRRDARGLTPLE 144 G LP+ LA VV++L + L D+ G T L Sbjct: 198 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLH 251 >2NYJ-A nrPDB Length = 273 Score = 63.8 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 38/160 (23%), Positives = 60/160 (37%), Gaps = 36/160 (22%) Query: 42 GKTALQVMMFGST-AIALELLKQGASPNVQDTS--------------GTSPVHDAARTGF 86 G+TAL + + + L++ GA G P+ AA T Sbjct: 101 GQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQ 160 Query: 87 LDTLKVLVEHG---ADVNVPDGTGALPIHLAVQE-----GHTAVV-----SFLAAESDLH 133 L +K L+++ AD++ D G +H V+ +T V L + LH Sbjct: 161 LAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLH 220 Query: 134 RR-------DARGLTPLELALQRGAQDLVD-ILQGHMVAP 165 + +GLTPL LA G ++ ILQ + P Sbjct: 221 PTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIHEP 260 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 46/155 (29%), Gaps = 34/155 (21%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNR--------------FGKTALQVMM-FGS 53 G A + LL A FG+ L + Sbjct: 101 GQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQ 160 Query: 54 TAIALELLKQG---ASPNVQDTSGTSPVHDAARTGF--LDTLKVL-------VEHGADV- 100 AI LL+ A + +D+ G + +H +D K + + GA + Sbjct: 161 LAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLH 220 Query: 101 ------NVPDGTGALPIHLAVQEGHTAVVSFLAAE 129 + + G P+ LA G V++++ Sbjct: 221 PTLKLEEITNRKGLTPLALAASSGKIGVLAYILQR 255 Score = 30.3 bits (67), Expect = 0.46, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 26/75 (34%), Gaps = 15/75 (20%) Query: 105 GTGALPIHLAVQE---GHTAVVSFLAAES----------DLHRRDAR--GLTPLELALQR 149 TG + A+ G ++ L + + D+ G T L +A++R Sbjct: 52 ETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIER 111 Query: 150 GAQDLVDILQGHMVA 164 LV +L + Sbjct: 112 RNMTLVTLLVENGAD 126 >4BSZ-B nrPDB Length = 202 Score = 63.4 bits (153), Expect = 5e-11, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 39/97 (40%), Gaps = 12/97 (12%) Query: 76 SPVHDAARTGFLDTLKVLVEHGAD----------VNVPDGTGALPIHLAVQEGHTAVVSF 125 + +H AA G ++T++ ++E + VN + TG +H A G VV Sbjct: 54 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKL 113 Query: 126 LA--AESDLHRRDARGLTPLELALQRGAQDLVDILQG 160 L E+D R+ G + A G +++ Sbjct: 114 LCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLK 150 Score = 56.5 bits (135), Expect = 5e-09, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 50/130 (38%), Gaps = 16/130 (12%) Query: 16 AARGDVQEVR----RLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELLK-------- 62 A GD+ ++ L+ EL+ + TAL G +L+ Sbjct: 22 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 81 Query: 63 --QGASPNVQDTSGTSPVHDAARTGFLDTLKVLV-EHGADVNVPDGTGALPIHLAVQEGH 119 A N + +G + +H A+ G LD +K+L E+ AD + + G I A G Sbjct: 82 EDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGK 141 Query: 120 TAVVSFLAAE 129 V ++ + Sbjct: 142 EEVETYFLKK 151 >6DVZ-A nrPDB Length = 791 Score = 63.0 bits (152), Expect = 6e-11, Method: Composition-based stats. Identities = 39/180 (21%), Positives = 66/180 (36%), Gaps = 40/180 (22%) Query: 20 DVQEVRRLLHRELVHPDALNRF-----------GKTALQVMM-FGSTAIALELLKQGASP 67 + +E+ R+L D L+RF G+TAL + + I L+ GA Sbjct: 182 NTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADV 241 Query: 68 NVQDTS--------------GTSPVHDAARTGFLDTLKVLVEH-GADVNVPDGTGALPIH 112 N G +P+ AA T + +++L+E+ D+ D G +H Sbjct: 242 NAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILH 301 Query: 113 LAVQEGHT-----AVVS-----FLAAESD---LHRRDARGLTPLELALQRGAQDLVDILQ 159 V V L + R+ GLTPL+LA + G +++ + Sbjct: 302 ALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYIL 361 Score = 46.9 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 25/154 (16%), Positives = 49/154 (31%), Gaps = 28/154 (18%) Query: 4 EEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNR--------------FGKTALQVM 49 EE G A ++ +L +A + FG+T L + Sbjct: 210 EEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALA 269 Query: 50 M-FGSTAIALELLKQ-GASPNVQDTSGTSPVHDAA-----RTGFLDTLK-----VLVEHG 97 I L++ QD+ G + +H D +K +L+ G Sbjct: 270 ACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSG 329 Query: 98 --ADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE 129 + + G P+ LA + G ++ ++ + Sbjct: 330 NWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 363 Score = 43.4 bits (101), Expect = 4e-05, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 63/182 (34%), Gaps = 58/182 (31%) Query: 15 AAARGDVQEVRRLLH---------RELVHPDALNRFGKTALQVMMFGSTAIALELLKQGA 65 A + G V+E+R LL R L PD L L G T + LL Sbjct: 126 AVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHK----LTASDTGKTCLMKALL--NI 179 Query: 66 SPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGT-----------GALPIHLA 114 +PN + + +++L+ + ++ D G +++A Sbjct: 180 NPNTK-----------------EIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIA 222 Query: 115 VQEGHTAVVSFL-AAESDLHRRDA--------------RGLTPLELALQRGAQDLVDILQ 159 ++ + + L AA +D++ G TPL LA ++V +L Sbjct: 223 IERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLM 282 Query: 160 GH 161 + Sbjct: 283 EN 284 >3W9G-A nrPDB Length = 260 Score = 60.7 bits (146), Expect = 3e-10, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 55/153 (35%), Gaps = 35/153 (22%) Query: 41 FGKTALQVMMFGS-TAIALELLKQGASPNVQDTS--------------GTSPVHDAARTG 85 G+TAL + + L+++GA + Q G P+ AA T Sbjct: 92 RGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 151 Query: 86 FLDTLKVLVEHG---ADVNVPDGTGALPIH--LAVQEGHTAVVSF--------------L 126 + L E+G AD+ D G +H +A+ + F L Sbjct: 152 QPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAKL 211 Query: 127 AAESDLHRR-DARGLTPLELALQRGAQDLVDIL 158 +++L + GL+PL +A + G + + Sbjct: 212 FPDTNLEALLNNDGLSPLMMAAKTGKIGIFQHI 244 >1DCQ-A nrPDB Length = 278 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 26/151 (17%), Positives = 53/151 (35%), Gaps = 13/151 (8%) Query: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGT 75 A + +L + FG LQ G L G P+ Sbjct: 120 ARKKHADTAAKLHSLCEA-VKTRDIFGL--LQAYADGVDLTEKIPLANGHEPD------E 170 Query: 76 SPVHDAARTGF---LDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SD 131 + +H A R+ L + LV++ +++ G G+ +H + + L + Sbjct: 171 TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKAS 230 Query: 132 LHRRDARGLTPLELALQRGAQDLVDILQGHM 162 + + G TPL++A + + ++L + Sbjct: 231 IEIANESGETPLDIAKRLKHEHCEELLTQAL 261 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 45/121 (37%), Gaps = 11/121 (9%) Query: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTA----IALELLKQGASP 67 L A A G + L PD TAL + + I L++ + Sbjct: 146 LLQAYADGVDLTEKIPLANGH-EPDE------TALHLAVRSVDRTSLHIVDFLVQNSGNL 198 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 + Q G++ +H T + LK+L+ A + + + +G P+ +A + H L Sbjct: 199 DKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLT 258 Query: 128 A 128 Sbjct: 259 Q 259 >2ETB-A nrPDB Length = 256 Score = 59.6 bits (143), Expect = 6e-10, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 61/164 (37%), Gaps = 36/164 (21%) Query: 33 VHPDALNRF--GKTALQVMMFGSTAIALELL-KQGASPNVQDTS-------------GTS 76 V+ + F G +AL + + + ++LL + GA +++ G Sbjct: 79 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 138 Query: 77 PVHDAARTGFLDTLKVLVEHG---ADVNVPDGTGALPIHLAVQ----------------E 117 P+ AA T D + L+E+ A + D G +H V + Sbjct: 139 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 198 Query: 118 GHTAVVSFLAAESDLH-RRDARGLTPLELALQRGAQDLVDILQG 160 G + + L L + +GLTPL+LA + G ++ + Sbjct: 199 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 242 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 39/174 (22%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKT-----------ALQVMMFGSTAIAL 58 DRL +RG +E+ LL + L T A+ + G A + Sbjct: 4 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 63 Query: 59 ELLKQGAS-------PNVQDTS----GTSPVHDAARTGFLDTLKVLVEHGADVNVPD--- 104 LL+ N Q T G S +H A L +K+LVE+GADV++ Sbjct: 64 PLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 123 Query: 105 ----------GTGALPIHLAVQEGHTAVVSFLAAE----SDLHRRDARGLTPLE 144 G LP+ LA VV++L + L D+ G T L Sbjct: 124 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLH 177 Score = 28.4 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 5/27 (18%), Positives = 14/27 (51%) Query: 138 RGLTPLELALQRGAQDLVDILQGHMVA 164 +G + L +A+++ + V +L + Sbjct: 89 QGHSALHIAIEKRSLQCVKLLVENGAD 115 >3LVQ-E nrPDB Length = 497 Score = 59.2 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 14/90 (15%), Positives = 36/90 (40%), Gaps = 4/90 (4%) Query: 78 VHDA---ARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLH 133 +H A A L + ++++G ++ G +H A + L + + Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 234 Query: 134 RRDARGLTPLELALQRGAQDLVDILQGHMV 163 + G T L++A ++ ++ ++L+ Sbjct: 235 TVNEAGETALDIARKKHHKECEELLEQAQA 264 Score = 54.2 bits (129), Expect = 2e-08, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 36/84 (42%) Query: 45 ALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPD 104 A++V S + +++ G + + G + +H AA D LK+L++ A V + Sbjct: 178 AVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVN 237 Query: 105 GTGALPIHLAVQEGHTAVVSFLAA 128 G + +A ++ H L Sbjct: 238 EAGETALDIARKKHHKECEELLEQ 261 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 33/85 (38%), Gaps = 7/85 (8%) Query: 30 RELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLD 88 + H DA G TAL + LLK A + +G + + A + + Sbjct: 195 QNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKE 254 Query: 89 TLKVLVEHGADVNVPDGTGALPIHL 113 ++L + A GT A P+H+ Sbjct: 255 CEELLEQAQA------GTFAFPLHV 273 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 28/72 (38%), Gaps = 5/72 (6%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPN 68 G+ AA + + +LL + +N G+TAL + ELL+Q Sbjct: 207 GNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQ----- 261 Query: 69 VQDTSGTSPVHD 80 Q + P+H Sbjct: 262 AQAGTFAFPLHV 273 >4N5Q-A nrPDB Length = 257 Score = 58.8 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 39/180 (21%), Positives = 66/180 (36%), Gaps = 40/180 (22%) Query: 20 DVQEVRRLLHRELVHPDALNRF-----------GKTALQVMM-FGSTAIALELLKQGASP 67 + +E+ R+L D L+RF G+TAL + + I L+ GA Sbjct: 66 NTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADV 125 Query: 68 NVQDTS--------------GTSPVHDAARTGFLDTLKVLVEH-GADVNVPDGTGALPIH 112 N G +P+ AA T + +++L+E+ D+ D G +H Sbjct: 126 NAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILH 185 Query: 113 LAVQEGHT-----AVVS-----FLAAESD---LHRRDARGLTPLELALQRGAQDLVDILQ 159 V V L + R+ GLTPL+LA + G +++ + Sbjct: 186 ALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYIL 245 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 25/154 (16%), Positives = 49/154 (31%), Gaps = 28/154 (18%) Query: 4 EEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNR--------------FGKTALQVM 49 EE G A ++ +L +A + FG+T L + Sbjct: 94 EEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALA 153 Query: 50 M-FGSTAIALELLKQ-GASPNVQDTSGTSPVHDAA-----RTGFLDTLK-----VLVEHG 97 I L++ QD+ G + +H D +K +L+ G Sbjct: 154 ACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSG 213 Query: 98 --ADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE 129 + + G P+ LA + G ++ ++ + Sbjct: 214 NWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 247 Score = 42.2 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 37/191 (19%), Positives = 67/191 (35%), Gaps = 58/191 (30%) Query: 6 VRAGDRLSGAAARGDVQEVRRLLH---------RELVHPDALNRFGKTALQVMMFGSTAI 56 +R R+ A + G V+E+R LL R L PD L L G T + Sbjct: 1 MRLKKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHK----LTASDTGKTCL 56 Query: 57 ALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGT---------- 106 LL +PN + + +++L+ + ++ D Sbjct: 57 MKALL--NINPNTK-----------------EIVRILLAFAEENDILDRFINAEYTEEAY 97 Query: 107 -GALPIHLAVQEGHTAVVSFL-AAESDLHRRDA--------------RGLTPLELALQRG 150 G +++A++ + + L AA +D++ G TPL LA Sbjct: 98 EGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTN 157 Query: 151 AQDLVDILQGH 161 ++V +L + Sbjct: 158 QPEIVQLLMEN 168 >6C8G-A nrPDB Length = 675 Score = 58.8 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 52/153 (33%), Gaps = 35/153 (22%) Query: 41 FGKTALQVMMFGS-TAIALELLKQGASPNVQDTS--------------GTSPVHDAARTG 85 G+TAL + + L+++GA + Q G P+ AA T Sbjct: 102 RGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 161 Query: 86 FLDTLKVLVEHG---ADVNVPDGTGALPIH--LAVQEGHTAVVSFLAAESDL-------- 132 D + L E+ AD+ D G +H +A+ + F+ DL Sbjct: 162 QPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKL 221 Query: 133 -------HRRDARGLTPLELALQRGAQDLVDIL 158 + ++PL +A + G + + Sbjct: 222 YPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHI 254 >6BBJ-A nrPDB Length = 868 Score = 58.8 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 52/153 (33%), Gaps = 35/153 (22%) Query: 41 FGKTALQVMMFGS-TAIALELLKQGASPNVQDTS--------------GTSPVHDAARTG 85 G+TAL + + L+++GA + Q G P+ AA T Sbjct: 233 RGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 292 Query: 86 FLDTLKVLVEHG---ADVNVPDGTGALPIH--LAVQEGHTAVVSFLAAESDL-------- 132 D + L E+ AD+ D G +H +A+ + F+ DL Sbjct: 293 QPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKL 352 Query: 133 -------HRRDARGLTPLELALQRGAQDLVDIL 158 + ++PL +A + G + + Sbjct: 353 YPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHI 385 >4DX2-A nrPDB Length = 259 Score = 57.7 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 32/153 (20%), Positives = 53/153 (34%), Gaps = 35/153 (22%) Query: 41 FGKTALQVMMFGS-TAIALELLKQGASPNVQDTS--------------GTSPVHDAARTG 85 G+TAL + + L+ QGA + Q G P+ AA T Sbjct: 90 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 149 Query: 86 FLDTLKVLVEH---GADVNVPDGTGALPIH--LAVQEGHTAVVSF--------------L 126 + L E+ AD+ D G +H +A+ + F L Sbjct: 150 QPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARL 209 Query: 127 AAESDLHR-RDARGLTPLELALQRGAQDLVDIL 158 +S+L + GL+PL +A + G + + Sbjct: 210 FPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHI 242 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 34/103 (33%), Gaps = 19/103 (18%) Query: 12 LSGAAARGDVQEVRRLLHREL--VHPDALNRFGKTALQVMMFGSTAIALE---------- 59 LS AA V L + G T L ++ + Sbjct: 142 LSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDL 201 Query: 60 LLKQGA----SPNVQ---DTSGTSPVHDAARTGFLDTLKVLVE 95 LL + A N++ + G SP+ AA+TG + + ++ Sbjct: 202 LLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIR 244 >2F37-A nrPDB Length = 251 Score = 57.3 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 34/164 (20%), Positives = 64/164 (39%), Gaps = 36/164 (21%) Query: 33 VHPDALNRF--GKTALQVMMFGSTAIALELL-KQGASPNVQDTS-------------GTS 76 V+ + + G +AL + + + ++LL + GA+ + + G Sbjct: 84 VNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGEL 143 Query: 77 PVHDAARTGFLDTLKVLVEHG---ADVNVPDGTGALPIHLAVQ-----EGHTAVVS---- 124 P+ AA T D + L+E+ A + D G +H V + A+V+ Sbjct: 144 PLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYD 203 Query: 125 -FLAAESDL-------HRRDARGLTPLELALQRGAQDLVDILQG 160 L A + L R+ + LTPL+LA + G ++ + Sbjct: 204 GLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQ 247 Score = 34.5 bits (78), Expect = 0.020, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 26/73 (35%), Gaps = 14/73 (19%) Query: 107 GALPIHLAVQEGHTAVVSFLAA-ESDLHRRD-------------ARGLTPLELALQRGAQ 152 G +H+A+++ V L +++H R G PL LA Sbjct: 95 GHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQW 154 Query: 153 DLVDILQGHMVAP 165 D+V L + P Sbjct: 155 DVVSYLLENPHQP 167 Score = 26.8 bits (58), Expect = 4.5, Method: Composition-based stats. Identities = 6/26 (23%), Positives = 14/26 (53%) Query: 138 RGLTPLELALQRGAQDLVDILQGHMV 163 RG + L +A+++ + V +L + Sbjct: 94 RGHSALHIAIEKRSLQCVKLLVENGA 119 >5UIL-A nrPDB Length = 405 Score = 56.9 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 54/124 (43%), Gaps = 6/124 (4%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASPN 68 + A D + + +L+ + + N +G + + V + G+ + L+ +GA+ N Sbjct: 280 KEILEACKYSDSKYIAKLIRAKSI-LFEKNIYGWSPVIVAAYHGNIELIKWLVSKGANIN 338 Query: 69 VQDTSGTSPVH----DAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS 124 ++ GT+ ++G LK+L++ G D+ + D + G+ ++ Sbjct: 339 DRNYKGTTVAMYFKDYMLKSGDYSGLKMLIDLGLDLTLTDYKDYTVFDYLEKSGNKNLLQ 398 Query: 125 FLAA 128 ++ A Sbjct: 399 YMMA 402 Score = 43.0 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 51/123 (41%), Gaps = 5/123 (4%) Query: 46 LQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDG 105 L+ + + +L++ + ++ G SPV AA G ++ +K LV GA++N + Sbjct: 283 LEACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGANINDRNY 342 Query: 106 TGALPIH----LAVQEGHTAVVSFLAA-ESDLHRRDARGLTPLELALQRGAQDLVDILQG 160 G ++ G + + L DL D + T + + G ++L+ + Sbjct: 343 KGTTVAMYFKDYMLKSGDYSGLKMLIDLGLDLTLTDYKDYTVFDYLEKSGNKNLLQYMMA 402 Query: 161 HMV 163 M Sbjct: 403 FMK 405 Score = 33.0 bits (74), Expect = 0.070, Method: Composition-based stats. Identities = 10/71 (14%), Positives = 31/71 (43%), Gaps = 1/71 (1%) Query: 72 TSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL-AAES 130 + +A + + L+ + + + G P+ +A G+ ++ +L + + Sbjct: 276 KDNFKEILEACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGA 335 Query: 131 DLHRRDARGLT 141 +++ R+ +G T Sbjct: 336 NINDRNYKGTT 346 >2B0O-E nrPDB Length = 301 Score = 56.9 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 14/90 (15%), Positives = 36/90 (40%), Gaps = 4/90 (4%) Query: 78 VHDA---ARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLH 133 +H A A L + ++++G ++ G +H A + L + + Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 253 Query: 134 RRDARGLTPLELALQRGAQDLVDILQGHMV 163 + G T L++A ++ ++ ++L+ Sbjct: 254 TVNEAGETALDIARKKHHKECEELLEQAQA 283 Score = 52.3 bits (124), Expect = 9e-08, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 36/84 (42%) Query: 45 ALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPD 104 A++V S + +++ G + + G + +H AA D LK+L++ A V + Sbjct: 197 AVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVN 256 Query: 105 GTGALPIHLAVQEGHTAVVSFLAA 128 G + +A ++ H L Sbjct: 257 EAGETALDIARKKHHKECEELLEQ 280 Score = 37.2 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 26/70 (37%), Gaps = 1/70 (1%) Query: 30 RELVHPDALNRFGKTALQVMM-FGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLD 88 + H DA G TAL + LLK A + +G + + A + + Sbjct: 214 QNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKE 273 Query: 89 TLKVLVEHGA 98 ++L + A Sbjct: 274 CEELLEQAQA 283 Score = 31.1 bits (69), Expect = 0.26, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 28/72 (38%), Gaps = 5/72 (6%) Query: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPN 68 G+ AA + + +LL + +N G+TAL + ELL+Q Sbjct: 226 GNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQ----- 280 Query: 69 VQDTSGTSPVHD 80 Q + P+H Sbjct: 281 AQAGTFAFPLHV 292 >6CV9-A nrPDB Length = 842 Score = 52.3 bits (124), Expect = 9e-08, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 6/84 (7%) Query: 80 DAARTGFLDTLKVLVE--HGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDA 137 DAA G + ++ ++E H +VN D G + LAV H + L + +L R Sbjct: 15 DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVG- 73 Query: 138 RGLTPLELALQRGAQDLVDILQGH 161 L LA+ +G +V+ + H Sbjct: 74 ---DALLLAISKGYVRIVEAILNH 94 Score = 49.6 bits (117), Expect = 6e-07, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 59/162 (36%), Gaps = 26/162 (16%) Query: 10 DRLSGAAARGDVQEVRRLLHREL-VHPDALNRFGKTALQVMMFG-STAIALELLKQGASP 67 +R AA G++ VR++L ++ + ++ G+ ALQ+ + I LLK+ Sbjct: 11 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLS 70 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLA 127 V D + A G++ ++ ++ H A LA + Sbjct: 71 RVGDA-----LLLAISKGYVRIVEAILNHPAFAEGK--------RLATSPSQSE-----L 112 Query: 128 AESDLHRRDARGL------TPLELALQRGAQDLVDILQGHMV 163 + D + D G TP+ LA ++V L Sbjct: 113 QQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGA 154 >6MHW-A nrPDB Length = 826 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 14/100 (14%) Query: 74 GTSPVHDAARTGFLDTLKVLVEH-GADVNVPDGTGALPIHLAVQEGHT-----AVVS--- 124 G +P+ AA T + +++L+EH D+ D G +H V V Sbjct: 263 GETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMY 322 Query: 125 --FLAAESD---LHRRDARGLTPLELALQRGAQDLVDILQ 159 L + R+ GLTPL+LA + G +++ + Sbjct: 323 DMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYIL 362 Score = 42.6 bits (99), Expect = 8e-05, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 37/103 (35%), Gaps = 14/103 (13%) Query: 41 FGKTALQVMM-FGSTAIALELLKQ-GASPNVQDTSGTSPVHDAA-----RTGFLDTLK-- 91 FG+T L + I L++ +D+ G + +H D +K Sbjct: 262 FGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRM 321 Query: 92 ---VLVEHG--ADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE 129 +L+ G + G P+ LA + G ++ ++ + Sbjct: 322 YDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSR 364 Score = 30.3 bits (67), Expect = 0.37, Method: Composition-based stats. Identities = 20/138 (14%), Positives = 44/138 (31%), Gaps = 32/138 (23%) Query: 53 STAIALELLKQGASPNVQDTSGTSPVHDAART---GFLDTLKVLVEHGADVNVPDGT--- 106 + L +G + + A + +++L+ + ++ Sbjct: 151 HDEDVPDFLMH---KLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINA 207 Query: 107 --------GALPIHLAV---QEGHTAVVSFLAAESDLHRRDAR------------GLTPL 143 G +++A+ Q A++ A+ + H + A G TPL Sbjct: 208 EYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPL 267 Query: 144 ELALQRGAQDLVDILQGH 161 LA ++V +L H Sbjct: 268 ALAACTNQPEIVQLLMEH 285 >6CUD-A nrPDB Length = 806 Score = 49.2 bits (116), Expect = 8e-07, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%) Query: 80 DAARTGFLDTLKVLVE--HGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDA 137 DAA G + ++ ++E +VN D G + LAV H V L + +L Sbjct: 33 DAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLA---R 89 Query: 138 RGLTPLELALQRGAQDLVDILQGH 161 G L LA+ +G +V+ + H Sbjct: 90 IGD-ALLLAISKGYVRIVEAILNH 112 Score = 46.1 bits (108), Expect = 7e-06, Method: Composition-based stats. Identities = 23/142 (16%), Positives = 51/142 (35%), Gaps = 33/142 (23%) Query: 46 LQVMMFGSTAIALELLKQGA--SPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVP 103 L +G+ + ++L++ + N D G + + A L+ ++L++ + Sbjct: 32 LDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIG 91 Query: 104 DGTGALPIHLAVQEGHTAVVSFL--------------------AAESDLHRRDARGL--- 140 D + LA+ +G+ +V + + D + D G Sbjct: 92 D-----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFS 146 Query: 141 ---TPLELALQRGAQDLVDILQ 159 TP+ LA ++V +L Sbjct: 147 PDITPIILAAHCQKYEVVHMLL 168 Score = 45.3 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 53/148 (35%), Gaps = 32/148 (21%) Query: 10 DRLSGAAARGDVQEVRRLLHRE-LVHPDALNRFGKTALQVMMFG-STAIALELLKQGASP 67 +R AA G++ VR++L ++ + ++ G+ ALQ+ + + LLK+ Sbjct: 29 ERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLA 88 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEH---GADVNVP----------------DGTGA 108 + D + A G++ ++ ++ H A + D G Sbjct: 89 RIGDA-----LLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGT 143 Query: 109 ------LPIHLAVQEGHTAVVSFLAAES 130 PI LA VV L + Sbjct: 144 RFSPDITPIILAAHCQKYEVVHMLLMKG 171 >4XD0-A nrPDB Length = 417 Score = 48.4 bits (114), Expect = 1e-06, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 49/122 (40%), Gaps = 6/122 (4%) Query: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGASPN 68 D + A + + +LL E + N G + + + + G+ + L+ +G + N Sbjct: 293 DEILTACEDKSPEFISKLLKTENI-LFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNIN 351 Query: 69 VQDTSGTSPVH----DAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS 124 ++ GT+ R+G L+ L+ G D+ + D G + + + + Sbjct: 352 DRNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIELFN 411 Query: 125 FL 126 F+ Sbjct: 412 FM 413 Score = 46.1 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 44/111 (39%), Gaps = 5/111 (4%) Query: 53 STAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIH 112 S +LLK ++ G SP+ AA G +D ++ LV G ++N + G Sbjct: 303 SPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRNYKGTTVAM 362 Query: 113 L-----AVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDIL 158 +T + + + DL +D GL+ + + +L + + Sbjct: 363 YFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIELFNFM 413 >6DJS-A nrPDB Length = 676 Score = 46.9 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%) Query: 80 DAARTGFLDTLKVLVE--HGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDA 137 DAA G + ++ ++E +VN D G + LAV H V L + +L Sbjct: 50 DAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLA---R 106 Query: 138 RGLTPLELALQRGAQDLVDILQGH 161 G L LA+ +G +V+ + H Sbjct: 107 IGD-ALLLAISKGYVRIVEAILNH 129 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 23/142 (16%), Positives = 51/142 (35%), Gaps = 33/142 (23%) Query: 46 LQVMMFGSTAIALELLKQGA--SPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVP 103 L +G+ + ++L++ + N D G + + A L+ ++L++ + Sbjct: 49 LDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIG 108 Query: 104 DGTGALPIHLAVQEGHTAVVSFL--------------------AAESDLHRRDARGL--- 140 D + LA+ +G+ +V + + D + D G Sbjct: 109 D-----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFS 163 Query: 141 ---TPLELALQRGAQDLVDILQ 159 TP+ LA ++V +L Sbjct: 164 PDITPIILAAHCQKYEVVHMLL 185 Score = 42.2 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 30/171 (17%), Positives = 58/171 (33%), Gaps = 32/171 (18%) Query: 10 DRLSGAAARGDVQEVRRLLHRE-LVHPDALNRFGKTALQVMMFG-STAIALELLKQGASP 67 +R AA G++ VR++L ++ + ++ G+ ALQ+ + + LLK+ Sbjct: 46 ERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLA 105 Query: 68 NVQDTSGTSPVHDAARTGFLDTLKVLVEH---GADVNVP----------------DGTGA 108 + D + A G++ ++ ++ H A + D G Sbjct: 106 RIGDA-----LLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGT 160 Query: 109 ------LPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQD 153 PI LA VV L + R +++ D Sbjct: 161 RFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHD 211 >6G1K-A nrPDB Length = 921 Score = 45.3 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 24/139 (17%), Positives = 48/139 (34%), Gaps = 25/139 (17%) Query: 10 DRLSGAAARGDVQEVRRLLHRELV----HPDALNRFGKTALQVMMFG-STAIALELLKQG 64 A +GD V+ L + + + ++ G+TAL + + + I LL Sbjct: 34 KSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFN 93 Query: 65 ASPNVQDTSGTSPVHDAARTGFLDTLKVLVEH-------GADVNVPDGTGA------LPI 111 G + +H A R + +++L+ H + D + PI Sbjct: 94 VYV------GDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPI 146 Query: 112 HLAVQEGHTAVVSFLAAES 130 LA + ++ L + Sbjct: 147 ILAAHTNNYEIIKMLVQKG 165 Score = 36.9 bits (84), Expect = 0.004, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 37/86 (43%), Gaps = 11/86 (12%) Query: 81 AARTGFLDTLKVLVEHGA-----DVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRR 135 A G ++K+ +E ++N D G + +A++ + ++ L + +++ Sbjct: 39 AVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLS-FNVYVG 97 Query: 136 DARGLTPLELALQRGAQDLVDILQGH 161 D L A+++ V++L H Sbjct: 98 D-----ALLHAIRKEVVGAVELLLNH 118 >5Z96-A nrPDB Length = 755 Score = 35.3 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 22/135 (16%), Positives = 48/135 (35%), Gaps = 23/135 (17%) Query: 13 SGAAARGDVQEVRRLLHRELV----HPDALNRFGKTALQVMMFGSTAIALELLKQGASPN 68 A +GD V++ L + + + ++ G+TAL + + +E + Sbjct: 37 LNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIE-----LLLS 91 Query: 69 VQDTSGTSPVHDAARTGFLDTLKVLVEH-------GADVNVPDGTGA------LPIHLAV 115 G + +H A R + +++L+ H + D + PI LA Sbjct: 92 FNVYVGDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAA 150 Query: 116 QEGHTAVVSFLAAES 130 + ++ L + Sbjct: 151 HTNNYEIIKLLVQKG 165 >5XE7-A nrPDB Length = 312 Score = 31.1 bits (69), Expect = 0.23, Method: Composition-based stats. Identities = 26/114 (22%), Positives = 36/114 (31%), Gaps = 8/114 (7%) Query: 21 VQEVRRLLHRELVHPDA-----LNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGT 75 Q V +LH P A L A Q+ A+ + P+ Sbjct: 122 DQRVAFVLHDGFAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDPDPAHNEVV 181 Query: 76 SPVHDAARTGFLDTLKVLVEHGADVNVP-DGTGALPIHLAVQEGHTAVVSFLAA 128 + A G LDT+ L+ DV D G P + G VV F+ Sbjct: 182 GRLMAAMAAGDLDTVVSLLH--PDVTFTGDSNGKAPTAVRAVRGSDKVVRFILG 233 Score = 29.2 bits (64), Expect = 0.88, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 11 RLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELL 61 RL A A GD+ V LLH ++ N TA++ + GS + +L Sbjct: 183 RLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVR-AVRGSDKVVRFIL 232 >4P98-A nrPDB Length = 317 Score = 29.2 bits (64), Expect = 0.84, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 26/73 (35%), Gaps = 1/73 (1%) Query: 32 LVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLK 91 +P A T + A LL +GA V G + AA G + T+ Sbjct: 169 AANPRASYEETYTGRFYDLQKEQEAARGLLDKGAQLLVATDDGRG-LGQAAVAGDVPTIG 227 Query: 92 VLVEHGADVNVPD 104 V GAD+ + Sbjct: 228 VSAAAGADIKAVN 240 >3NA5-A nrPDB Length = 570 Score = 28.0 bits (61), Expect = 1.9, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 16/32 (50%) Query: 79 HDAARTGFLDTLKVLVEHGADVNVPDGTGALP 110 H + F+ L+VL +G DV V + G P Sbjct: 112 HALSEPAFISVLEVLAANGVDVIVQENNGFTP 143 >4CJ9-A nrPDB Length = 794 Score = 27.6 bits (60), Expect = 2.3, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 40/99 (40%) Query: 52 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPI 111 G +L+ G + N + + T V AA +G LK ++EHG + + + Sbjct: 656 GGAQALKAVLEHGPTLNERGFNLTDIVEMAANSGGAQALKAVLEHGPTLRQRGLSLIDIV 715 Query: 112 HLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRG 150 +A G A+ + L L + + +A +RG Sbjct: 716 EIASNGGAQALKAVLKYGPVLMQAGRSNEEIVHVAARRG 754 >1OH2-P nrPDB Length = 413 Score = 27.2 bits (59), Expect = 3.3, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 41/118 (34%), Gaps = 20/118 (16%) Query: 36 DALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVE 95 +++ + T G + + L+ + +D++G DAA TG + L+ Sbjct: 170 NSVQNYILTMNHFA--GPLQMMVSGLRAKDNDERKDSNGNLAKGDAANTG----VHALLG 223 Query: 96 HGAD--VNVPDGTGALPIHLAVQEGHTAVVSF--------LAAESDLHRRDARGLTPL 143 D + DG+ + GH L +D R + G TPL Sbjct: 224 LHNDSFYGLRDGSSKTAL----LYGHGLGAEVKGIGSDGALRPGADTWRIASYGTTPL 277 >1EV4-A nrPDB Length = 221 Score = 27.2 bits (59), Expect = 3.7, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 15/39 (38%) Query: 107 GALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLEL 145 G +H G + FL A + + + +P +L Sbjct: 2 GKPVLHYFNARGRMECIRFLLAAAGVEFDEKFIQSPEDL 40 >5A9Q-4 nrPDB Length = 925 Score = 26.5 bits (57), Expect = 5.4, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 14/44 (31%) Query: 4 EEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQ 47 +EVR L G +E +RL R A G Sbjct: 342 DEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYH 385 >2DI3-A nrPDB Length = 239 Score = 26.5 bits (57), Expect = 5.7, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 12/28 (42%) Query: 138 RGLTPLELALQRGAQDLVDILQGHMVAP 165 G L + +RG D+ + L M P Sbjct: 106 EGWAALHSSAERGDWDVAEALLEKMDDP 133 >2X7Q-A nrPDB Length = 321 Score = 26.1 bits (56), Expect = 7.1, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 33/83 (39%), Gaps = 10/83 (12%) Query: 76 SPVHDAARTGF-------LDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 128 +P+ A + G+ ++ +KV G +N+ + + +A+ + Sbjct: 28 TPLFFAQQQGYYKAHDLSIEFVKVPEGSGRLINLLNSNE---VDIAIGLTEAFIADIAKG 84 Query: 129 ESDLHRRDARGLTPLELALQRGA 151 ++H D +PL A+ G+ Sbjct: 85 NENIHVLDTYVKSPLLWAVSTGS 107 >5KQW-A nrPDB Length = 479 Score = 26.1 bits (56), Expect = 8.3, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 31/83 (37%), Gaps = 15/83 (18%) Query: 76 SPVHDAARTGFLDTLKV--LVEHGADV------NVPDGTGALPIHLAVQEGHTAVVSFLA 127 P+ AA LD L+ L + ADV + + G P+ G V LA Sbjct: 349 HPICAAAALANLDILERENLTGNAADVGAYLQQRLRETFGGHPL-----VGEVRGVGMLA 403 Query: 128 AESDLHRRDARGLTPLELALQRG 150 + D TP + AL+ G Sbjct: 404 --ALEFMADKDARTPFDPALKVG 424 >6NJ0-A nrPDB Length = 451 Score = 25.7 bits (55), Expect = 9.4, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 33/92 (35%), Gaps = 9/92 (9%) Query: 47 QVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGT 106 + T + L G++ + T H A+ G L L+ G + D Sbjct: 127 HAATWQPTRLCSMTLTSGSTGLPKAAVHTYQAHLASAQGVLS----LIPFG---DHDDWL 179 Query: 107 GALPIHLAVQEGHTAVVSFLAAESDLHRRDAR 138 +LP+ G + +L A + + RD + Sbjct: 180 LSLPLFH--VSGQGIMWRWLYAGARMTVRDKQ 209 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.145 0.396 Lambda K H 0.267 0.0443 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,574,500 Number of Sequences: 36641 Number of extensions: 259524 Number of successful extensions: 1899 Number of sequences better than 10.0: 90 Number of HSP's better than 10.0 without gapping: 129 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 760 Number of HSP's gapped (non-prelim): 459 length of query: 166 length of database: 10,336,785 effective HSP length: 90 effective length of query: 76 effective length of database: 7,039,095 effective search space: 534971220 effective search space used: 534971220 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 55 (25.7 bits)