BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P55264 (361 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5KB6-A nrPDB 749 0.0 2I6B-A nrPDB 665 0.0 3LOO-A nrPDB 367 e-102 4N08-A nrPDB 260 7e-70 3UQ9-A nrPDB 239 2e-63 2AA0-A nrPDB 171 7e-43 4LC4-A nrPDB 81 8e-16 3UBO-A nrPDB 79 4e-15 1RK2-A nrPDB 64 8e-11 2C4E-A nrPDB 61 8e-10 6ILS-A nrPDB 56 2e-08 3H49-A nrPDB 50 1e-06 3HJ6-A nrPDB 50 1e-06 3RY7-A nrPDB 47 1e-05 2NWH-A nrPDB 46 2e-05 5ZWY-A nrPDB 45 5e-05 3LHX-A nrPDB 45 6e-05 1VM7-A nrPDB 43 2e-04 3KD6-A nrPDB 42 5e-04 5C40-A nrPDB 41 6e-04 2QHP-A nrPDB 40 0.001 1V1S-A nrPDB 40 0.002 4X8F-A nrPDB 39 0.002 3GBU-A nrPDB 39 0.004 1TYY-A nrPDB 38 0.007 2QCV-A nrPDB 37 0.018 3PL2-A nrPDB 36 0.020 4DU5-A nrPDB 35 0.055 6CW5-A nrPDB 35 0.065 3JUL-A nrPDB 34 0.082 5EYN-A nrPDB 34 0.11 2VAR-A nrPDB 33 0.21 4GM6-A nrPDB 32 0.31 3B1N-A nrPDB 32 0.40 3NCA-A nrPDB 31 1.0 4E84-A nrPDB 30 1.3 3DIN-A nrPDB 30 1.9 2RCM-A nrPDB 30 2.1 1U83-A nrPDB 29 2.8 3SBP-A nrPDB 29 3.1 6DEG-A nrPDB 29 3.3 4IDE-A nrPDB 29 3.9 4WJM-A nrPDB 28 4.3 2ABQ-A nrPDB 28 4.4 1POI-B nrPDB 28 5.2 3LJS-A nrPDB 28 5.9 3IQ0-A nrPDB 28 8.5 3AL6-A nrPDB 28 8.7 6C9R-A nrPDB 27 9.6 >5KB6-A nrPDB Length = 363 Score = 749 bits (1933), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/361 (100%), Positives = 361/361 (100%) Query: 1 MAAADEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDK 60 MAAADEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDK Sbjct: 3 MAAADEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDK 62 Query: 61 HKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAA 120 HKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAA Sbjct: 63 HKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAA 122 Query: 121 DAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARV 180 DAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARV Sbjct: 123 DAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARV 182 Query: 181 YYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNE 240 YYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNE Sbjct: 183 YYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNE 242 Query: 241 TEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPV 300 TEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPV Sbjct: 243 TEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPV 302 Query: 301 LDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF 360 LDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF Sbjct: 303 LDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF 362 Query: 361 H 361 H Sbjct: 363 H 363 >2I6B-A nrPDB Length = 345 Score = 665 bits (1717), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/343 (90%), Positives = 334/343 (97%) Query: 19 ALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHA 78 ++ EN+LFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHA Sbjct: 3 SVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHA 62 Query: 79 GGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGT 138 GGSTQNS+KVAQW+IQ+PHKAATFFGCIGIDKFGEILKRKAA+AHVDAHYYEQNEQPTGT Sbjct: 63 GGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGT 122 Query: 139 CAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKV 198 CAACITG NRSL+ANLAAANCYKKEKHLDLE+NW+LVEKARV YIAGFFLTVSPESVLKV Sbjct: 123 CAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKV 182 Query: 199 ARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIK 258 A +A+ENNR+FTLNLSAPFISQF+KE+LM VMPYVDILFGNETEAATFAREQGFETKDIK Sbjct: 183 AHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIK 242 Query: 259 EIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAF 318 EIAKK QALPK+NSKRQR VIFTQGRDDTI+A E++VTAF VLDQ+Q+EIIDTNGAGDAF Sbjct: 243 EIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAF 302 Query: 319 VGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDFH 361 VGGFLSQLVSDKPLTECIRAGHYAAS+IIRRTGCTFPEKPDFH Sbjct: 303 VGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH 345 >3LOO-A nrPDB Length = 365 Score = 367 bits (941), Expect = e-102, Method: Compositional matrix adjust. Identities = 175/345 (50%), Positives = 243/345 (70%), Gaps = 4/345 (1%) Query: 18 QALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYH 77 ++L + +L G+GNPLLDISAVV+KD L+KY ++PN+ ILAE+KH ++ EL++K++ EY Sbjct: 19 ESLRDGMLVGLGNPLLDISAVVEKDLLNKYDMQPNNAILAEEKHMPMYQELIEKYQAEYI 78 Query: 78 AGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTG 137 AGGS QNS++VAQW++Q P + A FFGC+G D++ IL+ +A V+ Y PTG Sbjct: 79 AGGSVQNSLRVAQWILQRP-RTAIFFGCVGQDEYARILEERATSNGVNVQYQRSATSPTG 137 Query: 138 TCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLK 197 TCA +TG RSL ANLAAAN + E HL + N ++ A+ +Y++GFF TVS ES L Sbjct: 138 TCAVLVTGTQRSLCANLAAANDFTPE-HLRSDGNRAYLQGAQFFYVSGFFFTVSFESALS 196 Query: 198 VARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDI 257 VA+ AA R+F +NLSAPF+ QF+K L ++ PYVD+LFGNETEA A+E + T+D+ Sbjct: 197 VAKEAAATGRMFMMNLSAPFVPQFYKNNLEEIFPYVDVLFGNETEAIALAKEFNYGTEDL 256 Query: 258 KEIAKKAQALPKVNSKRQRTVIFTQGRDDTIV--AAENDVTAFPVLDQNQEEIIDTNGAG 315 +EI K+ ALPK N KR+R VI TQG D ++ A ++V FPV E+++DTNGAG Sbjct: 257 REIGKRIAALPKENGKRKRIVIITQGSDPVLLIEAGTDNVREFPVQKLAPEQMVDTNGAG 316 Query: 316 DAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF 360 DAFVGGFL+QL+ + + CI+ G +AA II+R+GCTF +P F Sbjct: 317 DAFVGGFLAQLLQSRTVDVCIKCGIWAAREIIQRSGCTFEGEPSF 361 >4N08-A nrPDB Length = 348 Score = 260 bits (664), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 137/333 (41%), Positives = 197/333 (59%), Gaps = 4/333 (1%) Query: 30 NPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVA 89 NPLLD+SA V +FL KY L+ IL ++ K +FD++ K V Y GGS N +VA Sbjct: 16 NPLLDVSAHVSDEFLVKYGLERGTAILLSERQKGIFDDIEKMPNVRYVPGGSGLNVARVA 75 Query: 90 QWLIQEPHKA--ATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTCAACITGGN 147 QW+ Q+ +K T+ GCI D++G++LK A + + +G CA CITG Sbjct: 76 QWM-QQAYKGKFVTYVGCIADDRYGKVLKEAAEHEGIVMAVEHTTKAGSGACAVCITGKE 134 Query: 148 RSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNR 207 R+LVA+L AAN E H+ ++++R++Y +GF LTV VL+ R A E + Sbjct: 135 RTLVADLGAANHLSSE-HMRSPAVVRAMDESRIFYFSGFTLTVDVNHVLQACRKAREVDG 193 Query: 208 VFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQAL 267 +F +NLSAPFI QFF L +V+PY DI+ N EA FA ++T ++EIA++A + Sbjct: 194 LFMINLSAPFIMQFFSAQLGEVLPYTDIIVANRHEAKEFANMMKWDTDCVEEIARRAVSE 253 Query: 268 PKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLV 327 + R V+FT+ + T++A ++ V PV +Q+++ID NGAGDAF+GGFLS Sbjct: 254 VPYTGTKGRVVVFTRDIESTVLATKDGVETVPVPQLDQDKVIDMNGAGDAFMGGFLSAYA 313 Query: 328 SDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF 360 K L C GHY A +I+R GC+FPEKP F Sbjct: 314 VGKDLRRCCETGHYTAQEVIQRDGCSFPEKPSF 346 >3UQ9-A nrPDB Length = 372 Score = 239 bits (609), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 132/346 (38%), Positives = 207/346 (59%), Gaps = 8/346 (2%) Query: 20 LSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAG 79 LSE +FGMGNPLLDI D KY+LK ++ +LAE+KH ++DE+ KK K+ Y AG Sbjct: 24 LSEGYVFGMGNPLLDIIVDADDFMYRKYNLKKDNIVLAEEKHMTIYDEIQKKKKLNYIAG 83 Query: 80 GSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQP--TG 137 G+T N++K+ QW+IQ+P ++ GCIG D G+ +K + + + + E+P TG Sbjct: 84 GATLNTVKMIQWIIQKPF-VCSYVGCIGADIQGKYIKNDCSALDLVTEF-QIAEEPLMTG 141 Query: 138 TCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLK 197 A ++ RS+V L AA C H++ W LVEKA+VYYIAGF + E +LK Sbjct: 142 KVAVLVSEKLRSMVTYLGAA-CDLSLAHIEQPHVWSLVEKAQVYYIAGFVINTCYEGMLK 200 Query: 198 VARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDI 257 +A+++ EN ++F NLSAPF+SQF + + +++ Y +I+FGNE+EA + G + Sbjct: 201 IAKHSLENEKLFCFNLSAPFLSQFNTKEVDEMISYSNIVFGNESEAEAYGEVHGLLEDTV 260 Query: 258 KEIAKKAQALPKVNS-KRQRTVIFTQGRDDTIV--AAENDVTAFPVLDQNQEEIIDTNGA 314 A+ LP + KR+R VI T+G++ + ++++++ F V ++IIDTNGA Sbjct: 261 HATARYIADLPFADGKKRKRLVIITRGKNPLLYTDSSDSEIHQFMVEQFKDDQIIDTNGA 320 Query: 315 GDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF 360 GDAF GF++ + KP+ + A AA+ II R+G + + + Sbjct: 321 GDAFAAGFIADYIRGKPMITSLHAAVKAAAYIICRSGFSLGSRDSY 366 >2AA0-A nrPDB Length = 383 Score = 171 bits (432), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 116/366 (31%), Positives = 179/366 (48%), Gaps = 29/366 (7%) Query: 7 PKPKKLKVEAPQALSENV-LFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELF 65 P+ + V++ + + + +F +GNP+LD+ A V FLD++ LK D LA + ++ Sbjct: 16 PRGSHMAVDSSNSATGPMRVFAIGNPILDLVAEVPSSFLDEFFLKRGDATLATPEQMRIY 75 Query: 66 DELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVD 125 L +F GGS NS++V Q L+++P A + G IG D G++LK + Sbjct: 76 STL-DQFNPTSLPGGSALNSVRVVQKLLRKPGSAG-YMGAIGDDPRGQVLKELCDKEGLA 133 Query: 126 AHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWV-LVEKARVYYIA 184 + Q TG CA I R+L +L A ++ L +W A ++Y Sbjct: 134 TRFMVAPGQSTGVCAVLINEKERTLCTHLGACGSFR------LPEDWTTFASGALIFYAT 187 Query: 185 GFFLTVSPESVLKVARYA-AENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEA 243 + LT +P++ L+VA YA N +FTLNLSAPF + +K+A+ ++ + +ILFGNE E Sbjct: 188 AYTLTATPKNALEVAGYAHGIPNAIFTLNLSAPFCVELYKDAMQSLLLHTNILFGNEEEF 247 Query: 244 ATFAREQGF--ETKDIKEIAKKAQALPKV-----------NSKRQRTVIFTQGRDDTIVA 290 A A+ K A K A+ N+ + V+ T+G + I A Sbjct: 248 AHLAKVHNLVAAEKTALSTANKEHAVEVCTGALRLLTAGQNTSATKLVVMTRGHNPVIAA 307 Query: 291 AEN-DVTAFPVLDQNQ----EEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASV 345 + D T E+I+DTNGAGDAFVGGFL L K + +CI G+ A Sbjct: 308 EQTADGTVVVHEVGVPVVAAEKIVDTNGAGDAFVGGFLYALSQGKTVKQCIMCGNACAQD 367 Query: 346 IIRRTG 351 +I+ G Sbjct: 368 VIQHVG 373 >4LC4-A nrPDB Length = 352 Score = 80.9 bits (198), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 86/346 (24%), Positives = 152/346 (43%), Gaps = 43/346 (12%) Query: 18 QALSENVLFGMGNPLLDISAVVDKDFL-DKYSLKPNDQILAEDKHKELFDELVKKFKVEY 76 Q+++ + +GN ++DI + + FL D K ++ ++ + L+ + + Sbjct: 21 QSMTRFDVLTVGNAIVDIISRCNDQFLIDNQITKAAMNLIDAERAELLYSRMGPALEA-- 78 Query: 77 HAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQ-- 134 +GGS N+ A + KAA +FG + D+ G+I D +Y+ + Sbjct: 79 -SGGSAGNT---AAGVANLGGKAA-YFGNVAADQLGDIFTH---DIRAQGVHYQTKPKGA 130 Query: 135 --PTGTCAACIT-GGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLT-- 189 PT +T G RS+ L A E D+E + +V A+V Y G+ Sbjct: 131 FPPTARSMIFVTEDGERSMNTYLGACVELGPE---DVEAD--VVADAKVTYFEGYLWDPP 185 Query: 190 VSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPY--VDILFGNETEAATFA 247 + E++L AR A ++ R ++ LS F ++ +D+M VDI+F N EA + Sbjct: 186 RAKEAILDCARIAHQHGREMSMTLSDSFCVDRYRGEFLDLMRSGKVDIVFANRQEALSL- 244 Query: 248 REQGFETKDIKEIAKKAQALPKVN--SKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQ 305 ++T D +E + A K+ + + + +GR+ V A Sbjct: 245 ----YQTDDFEEALNRIAADCKIAAVTMSENGAVILKGRERYYVNA-----------IRI 289 Query: 306 EEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 E++DT GAGD F GFL + L +C + G AA ++I++ G Sbjct: 290 REVVDTTGAGDLFASGFLYGYTQGRSLEDCGKLGCLAAGIVIQQIG 335 >3UBO-A nrPDB Length = 354 Score = 78.6 bits (192), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 87/340 (25%), Positives = 147/340 (43%), Gaps = 51/340 (15%) Query: 28 MGNPLLDISAVVDKDFLDKYSL-KPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSM 86 +GN ++DI A D FL++ + K ++ D+ + L+ + + +GGS N+ Sbjct: 11 IGNAIVDIIARCDDSFLEENGIIKGAMNLINADRAELLYSRMGPAVEA---SGGSAGNTA 67 Query: 87 KVAQWLIQEPHKAATFFGCIGIDKFGEILKR--KAADAH-----VDAHYYEQNEQPTGTC 139 L A +FG + D+ GEI +A H +D H PT Sbjct: 68 AGVASL----GGRAAYFGKVADDQLGEIFTHDIRAQGVHFQTKPLDGH------PPTARS 117 Query: 140 AACIT-GGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLT--VSPESVL 196 +T G RS+ L A E D+E + +V +++V Y G+ + +++ Sbjct: 118 MIFVTEDGERSMNTYLGACVELGPE---DVEDD--VVAQSKVTYFEGYLWDPPRAKDAIR 172 Query: 197 KVARYAAENNRVFTLNLSAPFISQFFKEALMDVM--PYVDILFGNETEAATFAREQGFET 254 + AR A + R + LS F ++ +++M VDI+F N EA +ET Sbjct: 173 EAARIAHAHGRETAMTLSDSFCVHRYRSEFLELMRSGTVDIVFANRQEALAL-----YET 227 Query: 255 KDIK---EIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDT 311 +D E+ + L V + +V+ + AE VL+Q ++DT Sbjct: 228 EDFDRALELLARDCKLAAVTLSEEGSVV--------VRGAERVRVGASVLEQ----VVDT 275 Query: 312 NGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 GAGD + GFL S + L EC + G+ AA ++I + G Sbjct: 276 TGAGDLYAAGFLFGYTSGRSLEECSKLGNLAAGIVIGQIG 315 >1RK2-A nrPDB Length = 309 Score = 64.3 bits (155), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 70/254 (27%), Positives = 114/254 (44%), Gaps = 25/254 (9%) Query: 102 FFGCIGIDKFGEILKRKAADAHVDAHYYEQ-NEQPTGTCAACITGGNRSLVANLAAANCY 160 F C G D GE ++++ A ++D + TG + G +++ A AN Sbjct: 60 FIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVNGEGENVIGIHAGANAA 119 Query: 161 KKEKHLDLERNWVLVEKARVYYIAGFFLTV-SP-ESVLKVARYAAENNRVFTLNLSAPFI 218 L V ++ R+ + + + SP ESV+ A+ A +N + LN AP Sbjct: 120 -------LSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNKTIVALN-PAPA- 170 Query: 219 SQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTV 278 +E +++ VDI+ NETEA G ++ ++ AK AQ L + K RTV Sbjct: 171 ----RELPDELLALVDIITPNETEAEKLT---GIRVENDEDAAKAAQVL---HEKGIRTV 220 Query: 279 IFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRA 338 + T G + + P + + +DT AGD F G ++ L+ +KPL E IR Sbjct: 221 LITLGSRGVWASVNGEGQRVPGF---RVQAVDTIAAGDTFNGALITALLEEKPLPEAIRF 277 Query: 339 GHYAASVIIRRTGC 352 H AA++ + R G Sbjct: 278 AHAAAAIAVTRKGA 291 >2C4E-A nrPDB Length = 302 Score = 60.8 bits (146), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 65/281 (23%), Positives = 110/281 (39%), Gaps = 39/281 (13%) Query: 75 EYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKR--KAADAHVDAHYYEQN 132 +Y+ G + ++ + + + + C+G D +R K D ++ YY + Sbjct: 39 KYYGGAAANTAVGIKKLGVN-----SELLSCVGYDFKNSGYERYLKNLDINISKLYYSEE 93 Query: 133 EQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSP 192 E+ N+ AA YK+ + + +IA T P Sbjct: 94 EETPKAWIFTDKDNNQITFFLWGAAKHYKELNPPNFN--------TEIVHIA----TGDP 141 Query: 193 ESVLKVARYAAENNRV-FTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQG 251 E LK A+ A NN V F P Q+ KE L++++ + + LF N+ E + Sbjct: 142 EFNLKCAKKAYGNNLVSFDPGQDLP---QYSKEMLLEIIEHTNFLFMNKHEFERASNLLN 198 Query: 252 FETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDT 311 FE D E R +I T+G +++ ++ P + + +ID Sbjct: 199 FEIDDYLE--------------RVDALIVTKGSKGSVIYTKDKKIEIPCIKAGK--VIDP 242 Query: 312 NGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGC 352 GAGD++ GFLS V L +C G AS ++ GC Sbjct: 243 TGAGDSYRAGFLSAYVKGYDLEKCGLIGAATASFVVEAKGC 283 >6ILS-A nrPDB Length = 313 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 75/304 (24%), Positives = 123/304 (40%), Gaps = 62/304 (20%) Query: 78 AGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAAD----AHVDAHYYEQNE 133 AGG N L+ + F G +G D G+++ D H+D + N Sbjct: 38 AGGKGANQAACGAKLMYPTY----FVGRLGEDAHGKLIAEALGDDGCGVHLD-YVRSVNN 92 Query: 134 QPTGTCAACI-TGGNRSLV----ANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFL 188 +PTG + + G S++ AN+ A + L++ RN +V R Sbjct: 93 EPTGHAVVMLQSDGQNSIIIVGGANMKAWPEIMSDDDLEIVRNAGIVLLQREI------- 145 Query: 189 TVSPESV-LKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFA 247 P+S+ ++VA+ + L++ + L+D +DIL NETE + Sbjct: 146 ---PDSINIQVAKAVKKAGVPVILDVGG--MDTPIPNELLD---SIDILSPNETE---LS 194 Query: 248 REQGFETKDIKEIAKKA---------QALPKVNSKRQRTVIFTQGR---DDTIVAAENDV 295 R G T+ ++I++ Q L K+ SK + +F QG +I+ A Sbjct: 195 RLTGMPTETFEQISQAVAKCHKLGVKQVLVKLGSKG--SALFIQGEKPIQQSIIPAA--- 249 Query: 296 TAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFP 355 +++DT GAGD F F +V K EC+R AAS+ ++ G P Sbjct: 250 -----------QVVDTTGAGDTFTAAFAVAMVEGKSHEECLRFAAAAASLCVQVKG-AIP 297 Query: 356 EKPD 359 PD Sbjct: 298 SMPD 301 >3H49-A nrPDB Length = 325 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 68/297 (22%), Positives = 122/297 (41%), Gaps = 25/297 (8%) Query: 61 HKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAA 120 K +FD V + +E A + +++ A + + H+ A IG D G+ + Sbjct: 24 SKNIFD--VDSYPLERIAMTTGGDAINEATIISRLGHRTA-LMSRIGKDAAGQFILDHCR 80 Query: 121 DAHVDAHYYEQNEQ-PTGTCAACIT-GGNRSLVANLAAANCYKKEKHLDLERNWVLVEKA 178 ++D +Q+ T +T G R+ V N + +D R +A Sbjct: 81 KENIDIQSLKQDVSIDTSINVGLVTEDGERTFVTNRNGSLWKLNIDDVDFAR----FSQA 136 Query: 179 RVYYIAGFFLT--VSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDIL 236 ++ +A F + + +++ ++ A + ++ P +++ + + + + YVD L Sbjct: 137 KLLSLASIFNSPLLDGKALTEIFTQAKARQMIICADMIKPRLNETLDD-ICEALSYVDYL 195 Query: 237 FGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVT 296 F N EA G ET D EIA A +TV+ G+D + + Sbjct: 196 FPNFAEAKLLT---GKETLD--EIADCFLACG------VKTVVIKTGKDGCFIKRGDMTM 244 Query: 297 AFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCT 353 P + IDT GAGD F GF++ L+ K L EC R + A++ + G T Sbjct: 245 KVPAVAGITA--IDTIGAGDNFASGFIAALLEGKNLRECARFANATAAISVLSVGAT 299 >3HJ6-A nrPDB Length = 327 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 77/347 (22%), Positives = 131/347 (37%), Gaps = 47/347 (13%) Query: 21 SENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGG 80 E V+ G+ N +S K LD SL +IL + E + L + + H GG Sbjct: 3 GEGVIVGILNKNFSLS----KGDLDVVSLG---EILVDMISTEEVNSLSQSREYTRHFGG 55 Query: 81 STQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTCA 140 S N +A L + K A +G D FG L + +Q+++ T Sbjct: 56 SPAN---IAVNLSRLGKKVA-LISRLGADAFGNYLLDVLKGEQIITDGIQQDKERRTTIV 111 Query: 141 ACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSP--ESVLKV 198 A+ Y +E + E L+++++V++++ F L+ P ++ +K Sbjct: 112 YVSKSTRTPDWLPYREADMYLQEDDIIFE----LIKRSKVFHLSTFILSRKPARDTAIKA 167 Query: 199 ARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIK 258 YA E ++ + Y +L+ + A E +K Sbjct: 168 FNYAREQGKIVCFDPC-----------------YRKVLWPEGDDGAGVVEEIISRADFVK 210 Query: 259 EIAKKAQAL-----PKVNSKRQ-----RTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEI 308 A+ L P+ KR + VI T G + I + ++ P E+ Sbjct: 211 PSLDDARHLFGPDSPENYVKRYLELGVKAVILTLGEEGVIASDGEEIIRIPAF---SEDA 267 Query: 309 IDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFP 355 +D GAGDAF GF+ L+ + I+ G+ A+ IR G P Sbjct: 268 VDVTGAGDAFWSGFICGLLDGYTVKRSIKLGNGVAAFKIRGVGALSP 314 >3RY7-A nrPDB Length = 304 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 51/193 (26%), Positives = 81/193 (41%), Gaps = 30/193 (15%) Query: 180 VYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPF---ISQF--------------- 221 +Y G +T++PE V+ A+ A N L P IS F Sbjct: 109 IYVYGGANMTMTPEDVIN-AKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPA 167 Query: 222 -FKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIF 280 K +++ +DI+ NETEA + G + + + + A + K TV+ Sbjct: 168 PAKALPNELLSLIDIIVPNETEAELLS---GIKVTNEQSMKDNANYFLSIGIK---TVLI 221 Query: 281 TQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQL-VSDKPLTECIRAG 339 T G+ T A +N N IDT AGD F+G F+S+L S L + I G Sbjct: 222 TLGKQGTYFATKNQSQHIEAYKVNA---IDTTAAGDTFIGAFVSRLNKSQDNLADAIDFG 278 Query: 340 HYAASVIIRRTGC 352 + A+S+ +++ G Sbjct: 279 NKASSLTVQKHGA 291 >2NWH-A nrPDB Length = 317 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 15/132 (11%) Query: 222 FKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFT 281 K AL D+ DILF NE EA E +D I +KA V ++ V+ Sbjct: 176 LKAALGDI----DILFMNEAEARALTGETAENVRDWPNILRKAGLSGGVVTRGASEVVAF 231 Query: 282 QGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHY 341 G + I+ P L + E+ D GAGDA G+L+ + K + E +R G Sbjct: 232 NGTEKAIL--------HPPLIR---EVKDVTGAGDAMASGYLAAIAEGKTIREALRQGAA 280 Query: 342 AASVIIRRTGCT 353 AA++ ++ + T Sbjct: 281 AAAITVQSSFAT 292 >5ZWY-A nrPDB Length = 349 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 10/160 (6%) Query: 203 AENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAK 262 A + V+T+ SAP E + +PYV + NE EA G + D + Sbjct: 193 AHSRGVYTVFNSAPAPKPAEVEQIKPFLPYVSLFCPNEVEATLIT---GVKVTDTESAFS 249 Query: 263 KAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGF 322 +AL ++ R V+ T G V +EN V ++ + + DT GAGD FVG Sbjct: 250 AIKALQQLGV---RDVVITLGAAG-FVLSENGAEPVHVTGKHVKAV-DTTGAGDCFVGSM 304 Query: 323 LSQLVSDKPLTE-CIRAGHYAASVIIRR-TGCTFPEKPDF 360 + + + L E C RA AA + R+ T ++P + Sbjct: 305 VYFMSRGRNLLEACKRANECAAISVTRKGTQLSYPHPSEL 344 >3LHX-A nrPDB Length = 319 Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 1/83 (1%) Query: 276 RTVIFTQGRDDTIVA-AENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTE 334 + V+ +G D +V+ A + P + +E++IDT AGD+F G+L+ ++ Sbjct: 225 KEVVVKRGADSCLVSIAGEALVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGSAEN 284 Query: 335 CIRAGHYAASVIIRRTGCTFPEK 357 + GH AS +I+ G P + Sbjct: 285 AAKRGHLTASTVIQYRGAIIPRE 307 >1VM7-A nrPDB Length = 311 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 60/258 (23%), Positives = 104/258 (40%), Gaps = 31/258 (12%) Query: 97 HKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTCAACI--TGGNRSLVANL 154 K F CIG D + ++L + Y + PTG + TG NR ++ Sbjct: 66 EKGCRFVTCIGNDDYSDLLIENYEKLGITG--YIRVSLPTGRAFIEVDKTGQNRIII--F 121 Query: 155 AAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLS 214 AN K++ +D W + ++ + + + E+ L+ A+ R + + Sbjct: 122 PGANAELKKELID----WNTLSESDILLLQN---EIPFETTLECAK------RFNGIVIF 168 Query: 215 APFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKR 274 P +Q E ++ Y+D L NE E +++ E +++ A+K L N Sbjct: 169 DPAPAQGINE---EIFQYLDYLTPNEKEIEALSKDFFGEFLTVEKAAEKFLELGVKN--- 222 Query: 275 QRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTE 334 VI G ++ +N+ FP + + +DT AGD F G F L K E Sbjct: 223 ---VIVKLGDKGVLLVNKNEKKHFPTF---KVKAVDTTAAGDVFNGAFAVALSEGKNPEE 276 Query: 335 CIRAGHYAASVIIRRTGC 352 + G AA++ + R G Sbjct: 277 AVIFGTAAAAISVTRLGA 294 >3KD6-A nrPDB Length = 313 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 18/133 (13%) Query: 224 EALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQG 283 E L V+ VD+ N++EA + + + K A+ + ++ K T+I +G Sbjct: 160 EELKKVLARVDVFIVNDSEARLLSGD--------PNLVKTARIIREMGPK---TLIIKKG 208 Query: 284 RDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQL-----VSDKPLTECIRA 338 ++ +N + A P E I D GAGD F GGF+ L S+ + + + Sbjct: 209 EHGALLFTDNGIFAAPAF--PLESIYDPTGAGDTFAGGFIGHLARCGNTSEAEMRKAVLY 266 Query: 339 GHYAASVIIRRTG 351 G AS + + G Sbjct: 267 GSAMASFCVEQFG 279 >5C40-A nrPDB Length = 330 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 59/264 (22%), Positives = 111/264 (42%), Gaps = 30/264 (11%) Query: 106 IGIDKFGEILKRKAADAHVDAHY-YEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEK 164 +G D FG + + Y+ + TGT + + ++++ +A AN + Sbjct: 75 VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134 Query: 165 HLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFIS----Q 220 L N ++ +A+V L ++P + L+ A A + V TL AP I+ Q Sbjct: 135 DLRAAAN--VISRAKVMVCQ---LEITPATSLE-ALTMARRSGVKTLFNPAPAIADLDPQ 188 Query: 221 FFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIF 280 F+ + D+ NE+EA G + + A L K + + VI Sbjct: 189 FYTLS--------DVFCCNESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVII 234 Query: 281 TQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRA 338 T G + +V ++ + + + + + +DT GAGD+FVG F + L + + Sbjct: 235 TLGAEGCVVLSQTEPEPKHIPTE-KVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293 Query: 339 GHYAASVIIRRTGC--TFPEKPDF 360 ++ A+V ++ G ++P K D Sbjct: 294 SNFIAAVSVQAAGTQSSYPYKKDL 317 >2QHP-A nrPDB Length = 296 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 40/152 (26%), Positives = 71/152 (46%), Gaps = 12/152 (7%) Query: 207 RVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQA 266 ++F +NL F + KE L + +IL N+ E T +R G+ D+++ K Sbjct: 149 KIFDINLRQDF---YTKEVLRESFKRCNILKINDEELVTISRMFGYPGIDLQD--KCWIL 203 Query: 267 LPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQL 326 L K N K +I T G + + V V +F + + + DT GAGD+F F + + Sbjct: 204 LAKYNLK---MLILTCGINGSYVFTPG-VVSFQ--ETPKVPVADTVGAGDSFTAAFCASI 257 Query: 327 VSDKPLTECIRAGHYAASVIIRRTGCTFPEKP 358 ++ K + E + ++ + ++G PE P Sbjct: 258 LNGKSVPEAHKLAVEVSAYVCTQSG-AMPELP 288 >1V1S-A nrPDB Length = 309 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 78/297 (26%), Positives = 118/297 (39%), Gaps = 48/297 (16%) Query: 68 LVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAH 127 L K +E + GG+ N VA L + K F G +G D+ G +++ + VD Sbjct: 22 LRGKRLLEVYVGGAEVN---VAVALARLGVKVG-FVGRVGEDELGAMVEERLRAEGVDLT 77 Query: 128 YYEQNEQPTGTCAA--CITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAG 185 ++ + TG G R +A D + +E R +++G Sbjct: 78 HFRRAPGFTGLYLREYLPLGQGRVFYYRKGSAGSALAPGAFDPD----YLEGVRFLHLSG 133 Query: 186 FFLTVSPE----SVLKVARYAAENNRV-----FTLNLSAPFISQFFKEALMDVMPYVDIL 236 +SPE S+ + RV + L +P ++ F E +P VD+L Sbjct: 134 ITPALSPEARAFSLWAMEEAKRRGVRVSLDVNYRQTLWSPEEARGFLE---RALPGVDLL 190 Query: 237 FGNETEA-ATFAREQGFETKDIKEIAKKAQALPKVNSKR--QRTVIFTQGRDDTIVAAEN 293 F +E EA F R E A +A + P+V KR + F GR Sbjct: 191 FLSEEEAELLFGR---------VEEALRALSAPEVVLKRGAKGAWAFVDGR-------RV 234 Query: 294 DVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIR-AGHYAASVIIRR 349 + +AF V E +D GAGDAF G+L+ V P+ E +R A ASV R Sbjct: 235 EGSAFAV------EAVDPVGAGDAFAAGYLAGAVWGLPVEERLRLANLLGASVAASR 285 >4X8F-A nrPDB Length = 309 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 64/251 (25%), Positives = 96/251 (38%), Gaps = 21/251 (8%) Query: 102 FFGCIGIDKFG-EILKRKAADAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCY 160 F C+G D FG I + D A Q PTG ++ + + A AN Sbjct: 60 FIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANA- 118 Query: 161 KKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQ 220 K +E + + AR + L + +LK A+ A LN AP Sbjct: 119 -KLTAAAIEPDLAAIRDARYLLMQ---LETPLDGILKAAQEAKTAKTNVILN-PAPA--- 170 Query: 221 FFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIF 280 +E +++ VD++ NETEA G D + A AL + K VI Sbjct: 171 --RELPDELLKCVDLITPNETEAEVLT---GITVYDDSSAQQAADAL---HCKGIEIVII 222 Query: 281 TQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGH 340 T G ++ P + DT AGD F G ++ L+ + PL I+ H Sbjct: 223 TLGSKGVWLSQNGRGQRIPGF---VVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAH 279 Query: 341 YAASVIIRRTG 351 AA++ + R G Sbjct: 280 AAAAISVTRFG 290 >3GBU-A nrPDB Length = 313 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 60/260 (23%), Positives = 111/260 (42%), Gaps = 45/260 (17%) Query: 75 EYHAGGSTQN-SMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNE 133 E H GG+ N ++ V++ ++ ++ +G D FGE L + + +VD ++E Sbjct: 29 EKHPGGAPANVAVGVSRLGVK-----SSLISKVGNDPFGEYLIEELSKENVDTRGIVKDE 83 Query: 134 QP-TGTCAACITGGNRSLVANLAAANCYKKEKHLDL---ERNWVLVEKARVYYIAGFFLT 189 + TG + G + S + Y + ++ + NW +VE+A++ L Sbjct: 84 KKHTGIVFVQLKGASPSFL-------LYDDVAYFNMTLNDINWDIVEEAKIVNFGSVILA 136 Query: 190 VSP--ESVLKVARYAAENNRV-FTLNLSAPFI---SQFFKEALMDVMPYVDILFGNETEA 243 +P E+V+KV + ++ + F +NL + + L + + DI+ +E E Sbjct: 137 RNPSRETVMKVIKKIKGSSLIAFDVNLRLDLWRGQEEEMIKVLEESIKLADIVKASEEEV 196 Query: 244 ATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQ 303 + QG E K + PK F +++T+V DV ++ V Sbjct: 197 -LYLENQGVEVKG--SMLTAITLGPKG---------FRLIKNETVV----DVPSYNV--- 237 Query: 304 NQEEIIDTNGAGDAFVGGFL 323 +DT GAGDAF+ L Sbjct: 238 ---NPLDTTGAGDAFMAALL 254 >1TYY-A nrPDB Length = 339 Score = 37.7 bits (86), Expect = 0.007, Method: Compositional matrix adjust. Identities = 55/232 (23%), Positives = 84/232 (36%), Gaps = 25/232 (10%) Query: 102 FFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTC--AACITGGNRSLVANL-AAAN 158 F GC+G D G L++ D VD + + T G RS + A+ Sbjct: 69 FIGCLGDDDAGRFLRQVFQDNGVDVTFLRLDADLTSAVLIVNLTADGERSFTYLVHPGAD 128 Query: 159 CYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSP--ESVLKVARYAAENNR--VFTLNLS 214 Y + L R + +Y + LT P E+ L+ AR E +F +NL Sbjct: 129 TYVSPQDLPPFRQY------EWFYFSSIGLTDRPAREACLEGARRMREAGGYVLFDVNLR 182 Query: 215 APFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKR 274 + D +P L A+ + E + + A + Sbjct: 183 SKMWGN------TDEIPE---LIARSAALASICKVSADELCQLSGASHWQDARYYLRDLG 233 Query: 275 QRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQL 326 T I + G D ++ FP + +++DT GAGDAFVGG L L Sbjct: 234 CDTTIISLGADGALLITAEGEFHFPA---PRVDVVDTTGAGDAFVGGLLFTL 282 >2QCV-A nrPDB Length = 332 Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust. Identities = 43/190 (22%), Positives = 85/190 (44%), Gaps = 22/190 (11%) Query: 169 ERNWVLVEKARVYYIAGFFLTVSP--ESVLKVARYAAENNR--VFTLNLSAPFISQFFKE 224 E N + ++++ ++G L+ SP E+VLK R A N+ VF L+ P+ + +E Sbjct: 130 EVNEAYIRRSKLLLVSGTALSKSPSREAVLKAIRLAKRNDVKVVFELDYR-PYSWETPEE 188 Query: 225 ALMD---VMPYVDILFGNETEAATFAR--EQGFETKDIKEIAKKAQALPKVNSKRQRTVI 279 + V DI+ G E E+G + I+ + K + L + + + Sbjct: 189 TAVYYSLVAEQSDIVIGTREEFDVLENRTEKGDNDETIRYLFKHSPELIVIKHGVEGSFA 248 Query: 280 FTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAG 339 +T+ + A + +++ T GAGD++ FL L+S K + ++ G Sbjct: 249 YTKAGEAYRGYA------------YKTKVLKTFGAGDSYASAFLYALISGKGIETALKYG 296 Query: 340 HYAASVIIRR 349 +AS+++ + Sbjct: 297 SASASIVVSK 306 >3PL2-A nrPDB Length = 319 Score = 36.2 bits (82), Expect = 0.020, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 28/47 (59%) Query: 307 EIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCT 353 ++I+ GAGDAF G L+S+ PL + +R + A +++ R C+ Sbjct: 256 DVINGLGAGDAFGGALCHGLLSEWPLEKVLRFANTAGALVASRLECS 302 >4DU5-A nrPDB Length = 336 Score = 35.0 bits (79), Expect = 0.055, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 5/62 (8%) Query: 290 AAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRR 349 A V FPV E++DT GAGD F G +S L+ + E ++ G + + ++ Sbjct: 264 AGSGRVAGFPV-----AEVVDTVGAGDGFAVGVISALLDGLGVPEAVKRGAWIGARAVQV 318 Query: 350 TG 351 G Sbjct: 319 LG 320 >6CW5-A nrPDB Length = 332 Score = 34.7 bits (78), Expect = 0.065, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 25/47 (53%) Query: 305 QEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 Q + DT GAGD F G F++ L+S K L + ++ A + + G Sbjct: 270 QNPVKDTTGAGDCFAGYFVAGLMSGKSLQDALKTCLVACGICVENEG 316 >3JUL-A nrPDB Length = 320 Score = 34.3 bits (77), Expect = 0.082, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 28/43 (65%), Gaps = 1/43 (2%) Query: 313 GAGDAFVGGFLSQLVSDKPLTECIR-AGHYAASVIIRRTGCTF 354 GAGD FVG F++ L + P+TE ++ A +AS ++++ +F Sbjct: 250 GAGDVFVGAFIAGLAMNMPITETLKVATGCSASKVMQQDSSSF 292 >5EYN-A nrPDB Length = 323 Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust. Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 3/49 (6%) Query: 278 VIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQL 326 V+ T G +VA N ++ + IDT GAGDAFVGG L +L Sbjct: 231 VVVTLGAKGALVATPNSQQ---IVSGKAVKPIDTTGAGDAFVGGLLYRL 276 >2VAR-A nrPDB Length = 313 Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust. Identities = 65/287 (22%), Positives = 116/287 (40%), Gaps = 32/287 (11%) Query: 75 EYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGE-ILKRKAADAHVDAHYYEQNE 133 E H GS N +A + H + + +G D+FG+ I++ A +H NE Sbjct: 29 EKHVAGSELN-FCIA---VVRNHLSCSLIARVGNDEFGKNIIEYSRAQGIDTSHIKVDNE 84 Query: 134 QPTGTCAACITGG----NRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLT 189 TG I G +S + + + D+ N+V +R+ + G L Sbjct: 85 SFTGIY--FIQRGYPIPMKSELVYYRKGSAGSRLSPEDINENYV--RNSRLVHSTGITLA 140 Query: 190 VS---PESVLKVARYAAENNRVFTLNLSAPFISQF--FKEALMDVMPYVDILFGNETEAA 244 +S E+V+K A +R N+ S KE ++ ++ DI E Sbjct: 141 ISDNAKEAVIKAFELA--KSRSLDTNIRPKLWSSLEKAKETILSILKKYDI------EVL 192 Query: 245 TFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQN 304 + +TK + ++ +A K + +++ G I A +++V AF D Sbjct: 193 ITDPD---DTKILLDVTDPDEAYRKYKELGVKVLLYKLGSKGAI-AYKDNVKAFK--DAY 246 Query: 305 QEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 + + D GAGDA G F+S + K + + G A++++I G Sbjct: 247 KVPVEDPTGAGDAMAGTFVSLYLQGKDIEYSLAHGIAASTLVITVRG 293 >4GM6-A nrPDB Length = 351 Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust. Identities = 46/205 (22%), Positives = 82/205 (40%), Gaps = 31/205 (15%) Query: 158 NCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSP---ESVLKVARYAAENNR--VFTLN 212 + + + K +D + + L++ RV +++G + +S E V+K+ R A N F +N Sbjct: 132 SSFARHKSMDWDLS-ELLKGIRVLHVSGITIALSTFWLEMVVKIIREAKRNGIKISFDMN 190 Query: 213 LSAPFIS-QFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVN 271 A + K A ++P VD + +A F E ET D + ++ Sbjct: 191 YRAKLWELEAAKRAYQQLLPLVDYCSAGQMDAVAFF-EISSETTDYYQAMHDKYPNIELF 249 Query: 272 SKRQRTVI-----------FTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVG 320 +RTVI +TQG + +P I+D G GDA+ Sbjct: 250 YATKRTVISASHHLLQGHLWTQGE----CWESEEYAIYP--------IVDRVGGGDAYTA 297 Query: 321 GFLSQLVSDKPLTECIRAGHYAASV 345 L ++S+ E ++ AA + Sbjct: 298 AVLHGILSEWRPDETVKFATAAAGL 322 >3B1N-A nrPDB Length = 326 Score = 32.0 bits (71), Expect = 0.40, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 16/85 (18%) Query: 239 NETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAF 298 N+ EA + G+ EIA + QAL I T+G + + Sbjct: 192 NDYEAKLVCDKTGWSED---EIASRVQAL-----------IITRGEHGATIRHRDGTEQI 237 Query: 299 PVLDQNQEEIIDTNGAGDAFVGGFL 323 P + E +ID G GDAF GG L Sbjct: 238 PAV--RAERVIDPTGCGDAFRGGLL 260 >3NCA-A nrPDB Length = 313 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 61/304 (20%), Positives = 114/304 (37%), Gaps = 69/304 (22%) Query: 66 DELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEIL----KRKAAD 121 D ++ + GG+ NS V L+ P F G + + L +R+ D Sbjct: 42 DSEIRCLSQRWQRGGNASNSCTVLS-LLGAP---CAFMGSMAPGHVADFLVADFRRRGVD 97 Query: 122 AHVDAHYYEQNEQPTGTCAACITGGNRSLV---ANLAAANCYKKEKHLDLER-NWVLVEK 177 A + + + P+ C + GNR++V +L + EK +DL + W+ +E Sbjct: 98 VSQVA-WQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEK-VDLTQFKWIHIEG 155 Query: 178 ARVYYIAGFFLTVSPESVLKVARYAAENNRV-------FTLNLSAPFISQFFKEALMDVM 230 + E V + R A N R ++ + P +E L + Sbjct: 156 RN-----------ASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKP------REELFQLF 198 Query: 231 PYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFT--------- 281 Y D++F ++ A+ GF++ + +AL + + ++ + Sbjct: 199 GYGDVVFVSKD----VAKHLGFQSAE--------EALRGLYGRVRKGAVLVCAWAEEGAD 246 Query: 282 -QGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGH 340 G D ++ ++ AFP ++DT GAGD F + L + + E +R G Sbjct: 247 ALGPDGKLLHSD----AFP-----PPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGC 297 Query: 341 YAAS 344 A Sbjct: 298 QVAG 301 >4E84-A nrPDB Length = 352 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 12/46 (26%), Positives = 24/46 (52%) Query: 307 EIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGC 352 E+ D +GAGD + + L + PL + + + AA +++ + G Sbjct: 297 EVFDVSGAGDTVIATVATMLGAGVPLVDAVVLANRAAGIVVGKLGT 342 >3DIN-A nrPDB Length = 871 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 16/101 (15%) Query: 7 PKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKH----K 62 P KL +E Q E + F + L+++ V+DK YSL+ DQIL E + K Sbjct: 617 PMLSKL-IENIQKKVEGINFSIRKTLMEMDDVLDKQRRAVYSLR--DQILLEKDYDEYLK 673 Query: 63 ELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFF 103 ++F+++V E+ +G W I+ + +FF Sbjct: 674 DIFEDVVSTRVEEFCSG---------KNWDIESLKNSLSFF 705 >2RCM-A nrPDB Length = 495 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 3/47 (6%) Query: 7 PKPKKLKVEAPQALSENVLFGMGNPLLDISA--VVDKDFLDKYSLKP 51 P KLK +AP +++ VLF + +PLL I V+++ + +SL P Sbjct: 203 PADTKLKADAPGLITKWVLFNL-HPLLSIGLPRVIEEPLIHTFSLPP 248 >1U83-A nrPDB Length = 276 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 21/96 (21%), Positives = 43/96 (44%), Gaps = 5/96 (5%) Query: 12 LKVEAPQALSENVLFGMGNPLLDISAVVD--KDFLDKYSLKPNDQILAEDKHKELFDELV 69 ++ P+ +++L G PL + D++D +L +D +++ + Sbjct: 32 VRTNKPRETGQSILIDNGYPLQFFKDAIAGASDYIDFVKFGWGTSLLTKDLEEKI--STL 89 Query: 70 KKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGC 105 K+ + + GG T V+Q + E H+ T+FGC Sbjct: 90 KEHDITFFFGG-TLFEKYVSQKKVNEFHRYCTYFGC 124 >3SBP-A nrPDB Length = 638 Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 6/31 (19%) Query: 151 VANLAAANCYKKEKHLDL------ERNWVLV 175 AAA CY EK DL ER+WV+V Sbjct: 247 TGRFAAATCYNSEKAFDLGGMMRNERDWVVV 277 >6DEG-A nrPDB Length = 381 Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%) Query: 161 KKEKHL-DLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAP 216 K KHL D + + E+ R YY+ G + + + VLK+ A + +R+ +++ AP Sbjct: 143 SKLKHLLDCTQFAISTEETR-YYLNGIYFHIVHDDVLKLRLVATDGHRLAQVDMEAP 198 >4IDE-A nrPDB Length = 332 Score = 28.9 bits (63), Expect = 3.9, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 4/49 (8%) Query: 56 LAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFG 104 LA D KE F++L +KF V Y A G T ++K ++E K T G Sbjct: 222 LAIDYTKENFEDLPEKFDVVYDAVGETDKAVKA----VKEGGKVVTIVG 266 >4WJM-A nrPDB Length = 312 Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust. Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 16/93 (17%) Query: 276 RTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTE- 334 + V+ T+G + + P + + +++DT GAGD G L+ L S LT+ Sbjct: 218 KLVVITKGAHGAVAYTNHATVPVPGV---KVDVVDTVGAGDTVNAGILASLHSQGLLTKD 274 Query: 335 ------------CIRAGHYAASVIIRRTGCTFP 355 + G AA+V + R G P Sbjct: 275 ALANLSEDQIHSAVALGVRAAAVTVSRAGANPP 307 >2ABQ-A nrPDB Length = 306 Score = 28.5 bits (62), Expect = 4.4, Method: Compositional matrix adjust. Identities = 44/191 (23%), Positives = 75/191 (39%), Gaps = 33/191 (17%) Query: 155 AAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLK-VARYAAENNRVFTLNL 213 A KKE L +EK V +AG P+++ + + + A E ++ Sbjct: 103 GTAPLIKKEHVQALLEQLTELEKGDVLVLAGSVPQAMPQTIYRSMTQIAKERGAFVAVDT 162 Query: 214 SAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDI--KEIAKKAQALPKVN 271 S EAL +V+ +F + E ++ K IA A+P V Sbjct: 163 SG--------EALHEVL----------AAKPSFIKPNHHELSELVSKPIASIEDAIPHV- 203 Query: 272 SKRQRTVIFTQGRDDTIVAAENDVTAFPV------LDQNQEEIIDTNGAGDAFVGGFLSQ 325 QR + +G + +V+ D F ++ E+ ++ GAGD+ V GFL+ Sbjct: 204 ---QR--LIGEGIESILVSFAGDGALFASAEGMFHVNVPSGEVRNSVGAGDSVVAGFLAA 258 Query: 326 LVSDKPLTECI 336 L K L + + Sbjct: 259 LQEGKSLEDAV 269 >1POI-B nrPDB Length = 260 Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust. Identities = 13/51 (25%), Positives = 26/51 (50%) Query: 176 EKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEAL 226 EK + Y+A ++ T SPE VL+ + + ++ L P + + +E + Sbjct: 200 EKTKRMYLAAYYPTSSPEDVLENTGFDLDVSKAVELEAPDPAVIKLIREEI 250 >3LJS-A nrPDB Length = 338 Score = 28.1 bits (61), Expect = 5.9, Method: Compositional matrix adjust. Identities = 11/17 (64%), Positives = 14/17 (82%) Query: 307 EIIDTNGAGDAFVGGFL 323 ++ D+N AGDAFVGG L Sbjct: 253 QVQDSNAAGDAFVGGML 269 >3IQ0-A nrPDB Length = 330 Score = 27.7 bits (60), Expect = 8.5, Method: Compositional matrix adjust. Identities = 55/237 (23%), Positives = 94/237 (39%), Gaps = 44/237 (18%) Query: 105 CIGIDKFGEI-LKRKAADAHVDAHYYEQNEQPTGTCAACIT---GGNRSLVANLAAANCY 160 C+G D FG+I + R AAD + TG+ A +T G+R + N+ A C Sbjct: 59 CVGNDGFGDINIHRLAADGVDIRGISVLPLEATGS--AFVTYHNSGDRDFIFNIKNAACG 116 Query: 161 K-KEKHLDLERNWVLVEKARVYYIAG--FFLTVSPESVLKVARYAAENNRVFTLN----- 212 K +H+D +++ ++I G F ++V K N V + + Sbjct: 117 KLSAQHVDEN----ILKDCTHFHIMGSSLFSFHMVDAVKKAVTIVKANGGVISFDPNIRK 172 Query: 213 --LSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKV 270 L P + ++AL V+ DI +E E + E +A+ Sbjct: 173 EMLDIPEM----RDALHFVLELTDIYMPSEGEVLLLSPHSTPE-----------RAIAGF 217 Query: 271 NSKRQRTVIFTQGRDDTIVAAEND---VTAFPVLDQNQEEIIDTNGAGDAFVGGFLS 324 + + VI +G + N+ V ++PV E +D GAGD F G +++ Sbjct: 218 LEEGVKEVIVKRGNQGASYYSANEQFHVESYPV------EEVDPTGAGDCFGGAWIA 268 >3AL6-A nrPDB Length = 338 Score = 27.7 bits (60), Expect = 8.7, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 6/39 (15%) Query: 33 LDISAVVDKDFLDK---YSLKPNDQIL---AEDKHKELF 65 + ++AV DF+ K Y P DQ++ AE+KHKE F Sbjct: 83 IHVAAVAQMDFISKNFVYRTLPFDQLVQRAAEEKHKEFF 121 >6C9R-A nrPDB Length = 337 Score = 27.3 bits (59), Expect = 9.6, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 20/42 (47%) Query: 310 DTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 D G GDAF GFL+ + L + G A +++ TG Sbjct: 264 DPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTG 305 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5KB6-A nrPDB 494 e-140 2I6B-A nrPDB 462 e-130 3LOO-A nrPDB 402 e-112 4N08-A nrPDB 358 3e-99 3UQ9-A nrPDB 355 2e-98 2AA0-A nrPDB 314 3e-86 4LC4-A nrPDB 254 5e-68 3UBO-A nrPDB 237 4e-63 3HJ6-A nrPDB 226 1e-59 3H49-A nrPDB 211 4e-55 1VM7-A nrPDB 193 1e-49 2C4E-A nrPDB 190 1e-48 5C40-A nrPDB 181 4e-46 6ILS-A nrPDB 176 1e-44 5ZWY-A nrPDB 172 2e-43 1V1S-A nrPDB 168 4e-42 1RK2-A nrPDB 165 4e-41 3RY7-A nrPDB 148 3e-36 2QHP-A nrPDB 134 4e-32 3LHX-A nrPDB 122 2e-28 3KD6-A nrPDB 113 2e-25 2NWH-A nrPDB 112 3e-25 Sequences not found previously or not previously below threshold: 4X8F-A nrPDB 148 5e-36 1TYY-A nrPDB 119 2e-27 3GBU-A nrPDB 116 2e-26 2QCV-A nrPDB 110 9e-25 5EYN-A nrPDB 109 1e-24 2VAR-A nrPDB 108 3e-24 4DU5-A nrPDB 100 9e-22 3IQ0-A nrPDB 100 1e-21 4WJM-A nrPDB 95 6e-20 6CW5-A nrPDB 92 4e-19 1WYE-A nrPDB 90 2e-18 3PL2-A nrPDB 88 5e-18 3KZH-A nrPDB 86 3e-17 2AFB-A nrPDB 85 4e-17 2ABQ-A nrPDB 84 1e-16 4E69-A nrPDB 83 1e-16 3B1N-A nrPDB 83 1e-16 3NCA-A nrPDB 82 4e-16 2HW1-A nrPDB 81 7e-16 3I3Y-A nrPDB 77 1e-14 3LJS-A nrPDB 76 2e-14 6C9R-A nrPDB 76 2e-14 3N1C-A nrPDB 76 3e-14 3JUL-A nrPDB 74 9e-14 4GM6-A nrPDB 74 1e-13 2RBC-A nrPDB 72 3e-13 2AWD-A nrPDB 72 3e-13 4E84-A nrPDB 70 2e-12 3KTN-A nrPDB 69 3e-12 3BF5-A nrPDB 69 4e-12 2JG5-A nrPDB 67 1e-11 3GO6-A nrPDB 65 7e-11 2AJR-A nrPDB 64 8e-11 2Q5R-A nrPDB 57 1e-08 4S1M-A nrPDB 51 6e-07 2I5B-A nrPDB 48 9e-06 5YSQ-A nrPDB 47 1e-05 2DDM-A nrPDB 44 1e-04 3MBJ-A nrPDB 43 2e-04 3HYO-A nrPDB 40 0.002 5B6A-A nrPDB 39 0.003 5ZWB-B nrPDB 39 0.004 1YGJ-A nrPDB 39 0.004 4JJP-A nrPDB 39 0.004 2F7K-A nrPDB 37 0.013 1JXH-A nrPDB 36 0.023 4C5N-A nrPDB 35 0.039 3ZS7-A nrPDB 35 0.059 5TRW-A nrPDB 34 0.079 4XF7-A nrPDB 34 0.093 6AVO-A nrPDB 33 0.32 1POI-B nrPDB 32 0.40 5XGE-A nrPDB 31 0.60 2QEQ-A nrPDB 31 0.65 1UB0-A nrPDB 31 0.76 5TQI-A nrPDB 31 1.2 4BHD-A nrPDB 30 1.5 4QU2-A nrPDB 30 1.5 5AHK-A nrPDB 29 2.3 5U47-A nrPDB 29 2.6 3UNF-N nrPDB 29 3.6 1V59-A nrPDB 28 5.2 3LAD-A nrPDB 28 6.2 >5KB6-A nrPDB Length = 363 Score = 494 bits (1272), Expect = e-140, Method: Composition-based stats. Identities = 361/361 (100%), Positives = 361/361 (100%) Query: 1 MAAADEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDK 60 MAAADEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDK Sbjct: 3 MAAADEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDK 62 Query: 61 HKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAA 120 HKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAA Sbjct: 63 HKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAA 122 Query: 121 DAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARV 180 DAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARV Sbjct: 123 DAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARV 182 Query: 181 YYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNE 240 YYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNE Sbjct: 183 YYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNE 242 Query: 241 TEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPV 300 TEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPV Sbjct: 243 TEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPV 302 Query: 301 LDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF 360 LDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF Sbjct: 303 LDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF 362 Query: 361 H 361 H Sbjct: 363 H 363 >2I6B-A nrPDB Length = 345 Score = 462 bits (1188), Expect = e-130, Method: Composition-based stats. Identities = 312/343 (90%), Positives = 334/343 (97%) Query: 19 ALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHA 78 ++ EN+LFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHA Sbjct: 3 SVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHA 62 Query: 79 GGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGT 138 GGSTQNS+KVAQW+IQ+PHKAATFFGCIGIDKFGEILKRKAA+AHVDAHYYEQNEQPTGT Sbjct: 63 GGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGT 122 Query: 139 CAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKV 198 CAACITG NRSL+ANLAAANCYKKEKHLDLE+NW+LVEKARV YIAGFFLTVSPESVLKV Sbjct: 123 CAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKV 182 Query: 199 ARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIK 258 A +A+ENNR+FTLNLSAPFISQF+KE+LM VMPYVDILFGNETEAATFAREQGFETKDIK Sbjct: 183 AHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIK 242 Query: 259 EIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAF 318 EIAKK QALPK+NSKRQR VIFTQGRDDTI+A E++VTAF VLDQ+Q+EIIDTNGAGDAF Sbjct: 243 EIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAF 302 Query: 319 VGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDFH 361 VGGFLSQLVSDKPLTECIRAGHYAAS+IIRRTGCTFPEKPDFH Sbjct: 303 VGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH 345 >3LOO-A nrPDB Length = 365 Score = 402 bits (1032), Expect = e-112, Method: Composition-based stats. Identities = 176/356 (49%), Positives = 246/356 (69%), Gaps = 9/356 (2%) Query: 7 PKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFD 66 P+ + ++L + +L G+GNPLLDISAVV+KD L+KY ++PN+ ILAE+KH ++ Sbjct: 13 PRGSHM-----ESLRDGMLVGLGNPLLDISAVVEKDLLNKYDMQPNNAILAEEKHMPMYQ 67 Query: 67 ELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDA 126 EL++K++ EY AGGS QNS++VAQW++Q P + A FFGC+G D++ IL+ +A V+ Sbjct: 68 ELIEKYQAEYIAGGSVQNSLRVAQWILQRP-RTAIFFGCVGQDEYARILEERATSNGVNV 126 Query: 127 HYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGF 186 Y PTGTCA +TG RSL ANLAAAN + E HL + N ++ A+ +Y++GF Sbjct: 127 QYQRSATSPTGTCAVLVTGTQRSLCANLAAANDFTPE-HLRSDGNRAYLQGAQFFYVSGF 185 Query: 187 FLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATF 246 F TVS ES L VA+ AA R+F +NLSAPF+ QF+K L ++ PYVD+LFGNETEA Sbjct: 186 FFTVSFESALSVAKEAAATGRMFMMNLSAPFVPQFYKNNLEEIFPYVDVLFGNETEAIAL 245 Query: 247 AREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIV--AAENDVTAFPVLDQN 304 A+E + T+D++EI K+ ALPK N KR+R VI TQG D ++ A ++V FPV Sbjct: 246 AKEFNYGTEDLREIGKRIAALPKENGKRKRIVIITQGSDPVLLIEAGTDNVREFPVQKLA 305 Query: 305 QEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF 360 E+++DTNGAGDAFVGGFL+QL+ + + CI+ G +AA II+R+GCTF +P F Sbjct: 306 PEQMVDTNGAGDAFVGGFLAQLLQSRTVDVCIKCGIWAAREIIQRSGCTFEGEPSF 361 >4N08-A nrPDB Length = 348 Score = 358 bits (917), Expect = 3e-99, Method: Composition-based stats. Identities = 137/332 (41%), Positives = 195/332 (58%), Gaps = 2/332 (0%) Query: 30 NPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVA 89 NPLLD+SA V +FL KY L+ IL ++ K +FD++ K V Y GGS N +VA Sbjct: 16 NPLLDVSAHVSDEFLVKYGLERGTAILLSERQKGIFDDIEKMPNVRYVPGGSGLNVARVA 75 Query: 90 QWLIQE-PHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTCAACITGGNR 148 QW+ Q K T+ GCI D++G++LK A + + +G CA CITG R Sbjct: 76 QWMQQAYKGKFVTYVGCIADDRYGKVLKEAAEHEGIVMAVEHTTKAGSGACAVCITGKER 135 Query: 149 SLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRV 208 +LVA+L AAN E H+ ++++R++Y +GF LTV VL+ R A E + + Sbjct: 136 TLVADLGAANHLSSE-HMRSPAVVRAMDESRIFYFSGFTLTVDVNHVLQACRKAREVDGL 194 Query: 209 FTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALP 268 F +NLSAPFI QFF L +V+PY DI+ N EA FA ++T ++EIA++A + Sbjct: 195 FMINLSAPFIMQFFSAQLGEVLPYTDIIVANRHEAKEFANMMKWDTDCVEEIARRAVSEV 254 Query: 269 KVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVS 328 + R V+FT+ + T++A ++ V PV +Q+++ID NGAGDAF+GGFLS Sbjct: 255 PYTGTKGRVVVFTRDIESTVLATKDGVETVPVPQLDQDKVIDMNGAGDAFMGGFLSAYAV 314 Query: 329 DKPLTECIRAGHYAASVIIRRTGCTFPEKPDF 360 K L C GHY A +I+R GC+FPEKP F Sbjct: 315 GKDLRRCCETGHYTAQEVIQRDGCSFPEKPSF 346 >3UQ9-A nrPDB Length = 372 Score = 355 bits (910), Expect = 2e-98, Method: Composition-based stats. Identities = 133/359 (37%), Positives = 210/359 (58%), Gaps = 13/359 (3%) Query: 7 PKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFD 66 P+ + LSE +FGMGNPLLDI D KY+LK ++ +LAE+KH ++D Sbjct: 16 PRGSHM-----HDLSEGYVFGMGNPLLDIIVDADDFMYRKYNLKKDNIVLAEEKHMTIYD 70 Query: 67 ELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDA 126 E+ KK K+ Y AGG+T N++K+ QW+IQ+P ++ GCIG D G+ +K + + Sbjct: 71 EIQKKKKLNYIAGGATLNTVKMIQWIIQKPF-VCSYVGCIGADIQGKYIKNDCSALDLVT 129 Query: 127 HYYEQNEQP--TGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIA 184 + + E+P TG A ++ RS+V L AA C H++ W LVEKA+VYYIA Sbjct: 130 EF-QIAEEPLMTGKVAVLVSEKLRSMVTYLGAA-CDLSLAHIEQPHVWSLVEKAQVYYIA 187 Query: 185 GFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAA 244 GF + E +LK+A+++ EN ++F NLSAPF+SQF + + +++ Y +I+FGNE+EA Sbjct: 188 GFVINTCYEGMLKIAKHSLENEKLFCFNLSAPFLSQFNTKEVDEMISYSNIVFGNESEAE 247 Query: 245 TFAREQGFETKDIKEIAKKAQALPKVNS-KRQRTVIFTQGRDDTIV--AAENDVTAFPVL 301 + G + A+ LP + KR+R VI T+G++ + ++++++ F V Sbjct: 248 AYGEVHGLLEDTVHATARYIADLPFADGKKRKRLVIITRGKNPLLYTDSSDSEIHQFMVE 307 Query: 302 DQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDF 360 ++IIDTNGAGDAF GF++ + KP+ + A AA+ II R+G + + + Sbjct: 308 QFKDDQIIDTNGAGDAFAAGFIADYIRGKPMITSLHAAVKAAAYIICRSGFSLGSRDSY 366 >2AA0-A nrPDB Length = 383 Score = 314 bits (805), Expect = 3e-86, Method: Composition-based stats. Identities = 116/369 (31%), Positives = 179/369 (48%), Gaps = 29/369 (7%) Query: 7 PKPKKLKVEAPQALSENV-LFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELF 65 P+ + V++ + + + +F +GNP+LD+ A V FLD++ LK D LA + ++ Sbjct: 16 PRGSHMAVDSSNSATGPMRVFAIGNPILDLVAEVPSSFLDEFFLKRGDATLATPEQMRIY 75 Query: 66 DELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVD 125 L +F GGS NS++V Q L+++P A + G IG D G++LK + Sbjct: 76 STL-DQFNPTSLPGGSALNSVRVVQKLLRKPGSAG-YMGAIGDDPRGQVLKELCDKEGLA 133 Query: 126 AHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWV-LVEKARVYYIA 184 + Q TG CA I R+L +L A + L +W A ++Y Sbjct: 134 TRFMVAPGQSTGVCAVLINEKERTLCTHLGACGSF------RLPEDWTTFASGALIFYAT 187 Query: 185 GFFLTVSPESVLKVARYAA-ENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEA 243 + LT +P++ L+VA YA N +FTLNLSAPF + +K+A+ ++ + +ILFGNE E Sbjct: 188 AYTLTATPKNALEVAGYAHGIPNAIFTLNLSAPFCVELYKDAMQSLLLHTNILFGNEEEF 247 Query: 244 ATFAREQGF--ETKDIKEIAKKAQALPKV-----------NSKRQRTVIFTQGRDDTIVA 290 A A+ K A K A+ N+ + V+ T+G + I A Sbjct: 248 AHLAKVHNLVAAEKTALSTANKEHAVEVCTGALRLLTAGQNTSATKLVVMTRGHNPVIAA 307 Query: 291 AEND-----VTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASV 345 + V V E+I+DTNGAGDAFVGGFL L K + +CI G+ A Sbjct: 308 EQTADGTVVVHEVGVPVVAAEKIVDTNGAGDAFVGGFLYALSQGKTVKQCIMCGNACAQD 367 Query: 346 IIRRTGCTF 354 +I+ G + Sbjct: 368 VIQHVGFSL 376 >4LC4-A nrPDB Length = 352 Score = 254 bits (648), Expect = 5e-68, Method: Composition-based stats. Identities = 84/346 (24%), Positives = 147/346 (42%), Gaps = 43/346 (12%) Query: 18 QALSENVLFGMGNPLLDISAVVDKDFL-DKYSLKPNDQILAEDKHKELFDELVKKFKVEY 76 Q+++ + +GN ++DI + + FL D K ++ ++ + L+ + + Sbjct: 21 QSMTRFDVLTVGNAIVDIISRCNDQFLIDNQITKAAMNLIDAERAELLYSRMGPALEA-- 78 Query: 77 HAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNE--- 133 +GGS N+ A + KAA +FG + D+ G+I V +Y+ Sbjct: 79 -SGGSAGNT---AAGVANLGGKAA-YFGNVAADQLGDIFTHDIRAQGV---HYQTKPKGA 130 Query: 134 -QPTGTCAACIT-GGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLT-- 189 PT +T G RS+ L A E +V A+V Y G+ Sbjct: 131 FPPTARSMIFVTEDGERSMNTYLGACVELGPED-----VEADVVADAKVTYFEGYLWDPP 185 Query: 190 VSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPY--VDILFGNETEAATFA 247 + E++L AR A ++ R ++ LS F ++ +D+M VDI+F N EA + Sbjct: 186 RAKEAILDCARIAHQHGREMSMTLSDSFCVDRYRGEFLDLMRSGKVDIVFANRQEALSL- 244 Query: 248 REQGFETKDIKEIAKKAQALPKV--NSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQ 305 ++T D +E + A K+ + + + +GR+ V A Sbjct: 245 ----YQTDDFEEALNRIAADCKIAAVTMSENGAVILKGRERYYVNA-----------IRI 289 Query: 306 EEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 E++DT GAGD F GFL + L +C + G AA ++I++ G Sbjct: 290 REVVDTTGAGDLFASGFLYGYTQGRSLEDCGKLGCLAAGIVIQQIG 335 >3UBO-A nrPDB Length = 354 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 77/342 (22%), Positives = 143/342 (41%), Gaps = 39/342 (11%) Query: 20 LSENVLFGMGNPLLDISAVVDKDFLDKYSL-KPNDQILAEDKHKELFDELVKKFKVEYHA 78 +++ + +GN ++DI A D FL++ + K ++ D+ + L+ + + + Sbjct: 3 MAKYDVLTIGNAIVDIIARCDDSFLEENGIIKGAMNLINADRAELLYSRMGPAVEA---S 59 Query: 79 GGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNE----Q 134 GGS N+ L A +FG + D+ GEI V +++ Sbjct: 60 GGSAGNTAAGVASL----GGRAAYFGKVADDQLGEIFTHDIRAQGV---HFQTKPLDGHP 112 Query: 135 PTGTCAACIT-GGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLT--VS 191 PT +T G RS+ L A E D +V +++V Y G+ + Sbjct: 113 PTARSMIFVTEDGERSMNTYLGACVELGPEDVED-----DVVAQSKVTYFEGYLWDPPRA 167 Query: 192 PESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPY--VDILFGNETEAATFARE 249 +++ + AR A + R + LS F ++ +++M VDI+F N EA Sbjct: 168 KDAIREAARIAHAHGRETAMTLSDSFCVHRYRSEFLELMRSGTVDIVFANRQEALAL--- 224 Query: 250 QGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEII 309 +ET+D ++ ++ + T + ++V + E+++ Sbjct: 225 --YETEDFDRAL-------ELLARDCKLAAVTLSEEGSVVVRGAERVRVGASVL--EQVV 273 Query: 310 DTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 DT GAGD + GFL S + L EC + G+ AA ++I + G Sbjct: 274 DTTGAGDLYAAGFLFGYTSGRSLEECSKLGNLAAGIVIGQIG 315 >3HJ6-A nrPDB Length = 327 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 77/350 (22%), Positives = 131/350 (37%), Gaps = 47/350 (13%) Query: 21 SENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGG 80 E V+ G+ N +S K LD SL +IL + E + L + + H GG Sbjct: 3 GEGVIVGILNKNFSLS----KGDLDVVSLG---EILVDMISTEEVNSLSQSREYTRHFGG 55 Query: 81 STQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTCA 140 S N +A L + K A +G D FG L + +Q+++ T Sbjct: 56 SPAN---IAVNLSRLGKKVA-LISRLGADAFGNYLLDVLKGEQIITDGIQQDKERRTTIV 111 Query: 141 ACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSP--ESVLKV 198 A+ Y +E + E L+++++V++++ F L+ P ++ +K Sbjct: 112 YVSKSTRTPDWLPYREADMYLQEDDIIFE----LIKRSKVFHLSTFILSRKPARDTAIKA 167 Query: 199 ARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIK 258 YA E ++ + Y +L+ + A E +K Sbjct: 168 FNYAREQGKIVCFDPC-----------------YRKVLWPEGDDGAGVVEEIISRADFVK 210 Query: 259 EIAKKAQAL-----PKVNSKRQ-----RTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEI 308 A+ L P+ KR + VI T G + I + ++ P E+ Sbjct: 211 PSLDDARHLFGPDSPENYVKRYLELGVKAVILTLGEEGVIASDGEEIIRIPAF---SEDA 267 Query: 309 IDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKP 358 +D GAGDAF GF+ L+ + I+ G+ A+ IR G P Sbjct: 268 VDVTGAGDAFWSGFICGLLDGYTVKRSIKLGNGVAAFKIRGVGALSPVPS 317 >3H49-A nrPDB Length = 325 Score = 211 bits (537), Expect = 4e-55, Method: Composition-based stats. Identities = 68/317 (21%), Positives = 127/317 (40%), Gaps = 26/317 (8%) Query: 42 DFLDKYSLKPND-QILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAA 100 D LD + I + K +FD V + +E A + +++ A + + H+ A Sbjct: 4 DNLDVICIGAAIVDIPLQPVSKNIFD--VDSYPLERIAMTTGGDAINEATIISRLGHRTA 61 Query: 101 TFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQ-PTGTCAACIT-GGNRSLVANLAAAN 158 IG D G+ + ++D +Q+ T +T G R+ V N + Sbjct: 62 -LMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLVTEDGERTFVTNRNGSL 120 Query: 159 CYKKEKHLDLERNWVLVEKARVYYIAGFFLT--VSPESVLKVARYAAENNRVFTLNLSAP 216 +D R +A++ +A F + + +++ ++ A + ++ P Sbjct: 121 WKLNIDDVDFAR----FSQAKLLSLASIFNSPLLDGKALTEIFTQAKARQMIICADMIKP 176 Query: 217 FISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQR 276 +++ + + + + YVD LF N EA + + + EIA A + Sbjct: 177 RLNETLDD-ICEALSYVDYLFPNFAEAKLLTGK-----ETLDEIADCFLAC------GVK 224 Query: 277 TVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECI 336 TV+ G+D + + P + IDT GAGD F GF++ L+ K L EC Sbjct: 225 TVVIKTGKDGCFIKRGDMTMKVPAVAGIT--AIDTIGAGDNFASGFIAALLEGKNLRECA 282 Query: 337 RAGHYAASVIIRRTGCT 353 R + A++ + G T Sbjct: 283 RFANATAAISVLSVGAT 299 >1VM7-A nrPDB Length = 311 Score = 193 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 52/338 (15%) Query: 24 VLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQ 83 V+ +G+ +DI VD + KP E K ++ GG Sbjct: 16 VISVVGSSNIDIVLKVD------HFTKPG--------------ETQKAIEMNVFPGGKGA 55 Query: 84 NSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTCAACI 143 N A + + K F CIG D + ++L + Y + PTG + Sbjct: 56 NQ---AVTVAKIGEKGCRFVTCIGNDDYSDLLIENYEKLGITG--YIRVSLPTGRAFIEV 110 Query: 144 TGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAA 203 ++ + AN K++ +D W + ++ + + + E+ L+ A+ Sbjct: 111 DKTGQNRIIIFPGANAELKKELID----WNTLSESDILLLQN---EIPFETTLECAK--- 160 Query: 204 ENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKK 263 R + + P +Q E ++ Y+D L NE E +++ E +++ A+K Sbjct: 161 ---RFNGIVIFDPAPAQGINE---EIFQYLDYLTPNEKEIEALSKDFFGEFLTVEKAAEK 214 Query: 264 AQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFL 323 L N VI G ++ +N+ FP + + +DT AGD F G F Sbjct: 215 FLELGVKN------VIVKLGDKGVLLVNKNEKKHFPTF---KVKAVDTTAAGDVFNGAFA 265 Query: 324 SQLVSDKPLTECIRAGHYAASVIIRRTGC--TFPEKPD 359 L K E + G AA++ + R G + P + + Sbjct: 266 VALSEGKNPEEAVIFGTAAAAISVTRLGAQSSIPAREE 303 >2C4E-A nrPDB Length = 302 Score = 190 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 66/290 (22%), Positives = 110/290 (37%), Gaps = 38/290 (13%) Query: 66 DELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAA--DAH 123 + ++ + GG+ N+ + L + C+G D +R D + Sbjct: 29 NTSIQIPSARKYYGGAAANTAVGIKKL----GVNSELLSCVGYDFKNSGYERYLKNLDIN 84 Query: 124 VDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYI 183 + YY + E+ N+ AA YK+ + + +I Sbjct: 85 ISKLYYSEEEETPKAWIFTDKDNNQITFFLWGAAKHYKELNPPNFN--------TEIVHI 136 Query: 184 AGFFLTVSPESVLKVARYAAENNRV-FTLNLSAPFISQFFKEALMDVMPYVDILFGNETE 242 A T PE LK A+ A NN V F P Q+ KE L++++ + + LF N+ E Sbjct: 137 A----TGDPEFNLKCAKKAYGNNLVSFDPGQDLP---QYSKEMLLEIIEHTNFLFMNKHE 189 Query: 243 AATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLD 302 + FE D E R +I T+G +++ ++ P + Sbjct: 190 FERASNLLNFEIDDYLE--------------RVDALIVTKGSKGSVIYTKDKKIEIPCIK 235 Query: 303 QNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGC 352 ++ID GAGD++ GFLS V L +C G AS ++ GC Sbjct: 236 AG--KVIDPTGAGDSYRAGFLSAYVKGYDLEKCGLIGAATASFVVEAKGC 283 >5C40-A nrPDB Length = 330 Score = 181 bits (459), Expect = 4e-46, Method: Composition-based stats. Identities = 62/288 (21%), Positives = 112/288 (38%), Gaps = 26/288 (9%) Query: 78 AGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHY-YEQNEQPT 136 GG N A L +G D FG + + Y+ + T Sbjct: 51 FGGKGANQCVQAARLGAMTSMVC----KVGKDSFGNDYIENLKQNDISTEFTYQTKDAAT 106 Query: 137 GTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVL 196 GT + + ++++ +A AN + L N ++ +A+V L ++P + L Sbjct: 107 GTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAAN--VISRAKVMVCQ---LEITPATSL 161 Query: 197 KVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKD 256 + A A + V TL AP I+ D+ NE+EA G Sbjct: 162 E-ALTMARRSGVKTLFNPAPAIADLDP----QFYTLSDVFCCNESEAEILT---GLTVGS 213 Query: 257 IKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGD 316 + + A L K + + VI T G + +V ++ + + + + + +DT GAGD Sbjct: 214 AADAGEAALVLLK---RGCQVVIITLGAEGCVVLSQTEPEPKHIPTE-KVKAVDTTGAGD 269 Query: 317 AFVG--GFLSQLVSDKPLTECIRAGHYAASVIIRRTGC--TFPEKPDF 360 +FVG F + L + + ++ A+V ++ G ++P K D Sbjct: 270 SFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317 >6ILS-A nrPDB Length = 313 Score = 176 bits (446), Expect = 1e-44, Method: Composition-based stats. Identities = 70/318 (22%), Positives = 122/318 (38%), Gaps = 36/318 (11%) Query: 51 PNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDK 110 N I E + E + + AGG N L+ + F G +G D Sbjct: 11 ANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTY----FVGRLGEDA 66 Query: 111 FGEILKRKAADAHVDAH---YYEQNEQPTGTCAACI-TGGNRSLV----ANLAAANCYKK 162 G+++ D H N +PTG + + G S++ AN+ A Sbjct: 67 HGKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAWPEIMS 126 Query: 163 EKHLDLERNWVLVEKARVYYIAGFFLTVSPESV-LKVARYAAENNRVFTLNLSAPFISQF 221 + L++ RN +V R P+S+ ++VA+ + L++ Sbjct: 127 DDDLEIVRNAGIVLLQREI----------PDSINIQVAKAVKKAGVPVILDVGG-----M 171 Query: 222 FKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFT 281 +++ +DIL NETE +R G T+ ++I++ K+ K+ V+ Sbjct: 172 DTPIPNELLDSIDILSPNETE---LSRLTGMPTETFEQISQAVAKCHKLGVKQ---VLVK 225 Query: 282 QGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHY 341 G + + + + +++DT GAGD F F +V K EC+R Sbjct: 226 LGSKGSALFIQGEK-PIQQSIIPAAQVVDTTGAGDTFTAAFAVAMVEGKSHEECLRFAAA 284 Query: 342 AASVIIRRTGCTFPEKPD 359 AAS+ ++ G P PD Sbjct: 285 AASLCVQVKGA-IPSMPD 301 >5ZWY-A nrPDB Length = 349 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 72/363 (19%), Positives = 122/363 (33%), Gaps = 43/363 (11%) Query: 7 PKPKKL----KVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHK 62 P+ + V + + +G+ LD VD H Sbjct: 16 PRGSHMHRARNVRSHTGEYAPDILVVGSCFLDYVGYVD--------------------HM 55 Query: 63 ELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADA 122 E + GG N A + K A +G D G ++ Sbjct: 56 PQVGETMHSVSFHKGFGGKGANQ---AVAAGRLGAKVA-MVSMVGTDGDGSDYIKELERN 111 Query: 123 HVDAHY-YEQNEQPTGTCAACI--TGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKAR 179 VD Y + + TG + N +V A N + E N+ + Sbjct: 112 GVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHFTPELLRAQTNNYERILHTG 171 Query: 180 VYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGN 239 + Y+ + + L + A V+T+ SAP E + +PYV + N Sbjct: 172 LKYL-ICQNEIPLPTTLDTIKEAHSRG-VYTVFNSAPAPKPAEVEQIKPFLPYVSLFCPN 229 Query: 240 ETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFP 299 E EA G + D + +AL ++ R V+ T G V +EN Sbjct: 230 EVEATLIT---GVKVTDTESAFSAIKALQQLGV---RDVVITLGAAG-FVLSENGAEPVH 282 Query: 300 VLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGC--TFPEK 357 V ++ + +DT GAGD FVG + + + L E + + A++ + R G ++P Sbjct: 283 VTGKH-VKAVDTTGAGDCFVGSMVYFMSRGRNLLEACKRANECAAISVTRKGTQLSYPHP 341 Query: 358 PDF 360 + Sbjct: 342 SEL 344 >1V1S-A nrPDB Length = 309 Score = 168 bits (425), Expect = 4e-42, Method: Composition-based stats. Identities = 65/295 (22%), Positives = 108/295 (36%), Gaps = 41/295 (13%) Query: 68 LVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAH 127 L K +E + GG+ N VA L + K F G +G D+ G +++ + VD Sbjct: 22 LRGKRLLEVYVGGAEVN---VAVALARLGVKVG-FVGRVGEDELGAMVEERLRAEGVDLT 77 Query: 128 YYEQNEQPTGTCA--ACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAG 185 ++ + TG G R +A D + +E R +++G Sbjct: 78 HFRRAPGFTGLYLREYLPLGQGRVFYYRKGSAGSALAPGAFDPD----YLEGVRFLHLSG 133 Query: 186 FFLTVSPE----SVLKVARYAAENNRV-----FTLNLSAPFISQFFKEALMDVMPYVDIL 236 +SPE S+ + RV + L +P ++ F L +P VD+L Sbjct: 134 ITPALSPEARAFSLWAMEEAKRRGVRVSLDVNYRQTLWSPEEARGF---LERALPGVDLL 190 Query: 237 FGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVT 296 F +E EA E A +A + P+ V+ +G + Sbjct: 191 FLSEEEAELLFGRV--------EEALRALSAPE--------VVLKRGAKGAWAFVDGRRV 234 Query: 297 AFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 E +D GAGDAF G+L+ V P+ E +R + + + G Sbjct: 235 EGSAFA---VEAVDPVGAGDAFAAGYLAGAVWGLPVEERLRLANLLGASVAASRG 286 >1RK2-A nrPDB Length = 309 Score = 165 bits (416), Expect = 4e-41, Method: Composition-based stats. Identities = 72/288 (25%), Positives = 119/288 (41%), Gaps = 30/288 (10%) Query: 74 VEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQ-N 132 + GG N A F C G D GE ++++ A ++D Sbjct: 36 YQVAFGGKGANQAVAAG----RSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIK 91 Query: 133 EQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTV-- 190 + TG + G +++ A AN ++ ++ R+ + + + Sbjct: 92 GESTGVALIFVNGEGENVIGIHAGANAALSPALVE-------AQRERIANASALLMQLES 144 Query: 191 SPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQ 250 ESV+ A+ A +N + LN AP +E +++ VDI+ NETEA Sbjct: 145 PLESVMAAAKIAHQNKTIVALN-PAPA-----RELPDELLALVDIITPNETEAEKLT--- 195 Query: 251 GFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIID 310 G ++ ++ AK AQ L + K RTV+ T G + + P + + +D Sbjct: 196 GIRVENDEDAAKAAQVL---HEKGIRTVLITLGSRGVWASVNGEGQRVPGF---RVQAVD 249 Query: 311 TNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKP 358 T AGD F G ++ L+ +KPL E IR H AA++ + R G P P Sbjct: 250 TIAAGDTFNGALITALLEEKPLPEAIRFAHAAAAIAVTRKGAQ-PSVP 296 >3RY7-A nrPDB Length = 304 Score = 148 bits (374), Expect = 3e-36, Method: Composition-based stats. Identities = 68/327 (20%), Positives = 121/327 (37%), Gaps = 38/327 (11%) Query: 28 MGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSMK 87 M N ++ + + FL + L ++ ++ F GG N Sbjct: 1 MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAF------------GGGKGANQAI 48 Query: 88 VAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYY-EQNEQPTGTCAACITGG 146 + TF IG D + + AH+D Y + E TG + Sbjct: 49 ATARM----QADTTFITKIGTDGVADFILEDFKVAHIDTSYIIKTAEAKTGQAFITVNAE 104 Query: 147 NRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENN 206 ++ + AN + + ++ ++ A L V +++ A + Sbjct: 105 GQNTIYVYGGANMTMTPEDVINAKDAII--NADFVVAQ---LEVPIPAIISAFEIAKAHG 159 Query: 207 RVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQA 266 V T+ AP K +++ +DI+ NETEA + G + + + + A Sbjct: 160 -VTTVLNPAPA-----KALPNELLSLIDIIVPNETEAELLS---GIKVTNEQSMKDNANY 210 Query: 267 LPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQL 326 + K TV+ T G+ T A +N N IDT AGD F+G F+S+L Sbjct: 211 FLSIGIK---TVLITLGKQGTYFATKNQSQHIEAYKVN---AIDTTAAGDTFIGAFVSRL 264 Query: 327 -VSDKPLTECIRAGHYAASVIIRRTGC 352 S L + I G+ A+S+ +++ G Sbjct: 265 NKSQDNLADAIDFGNKASSLTVQKHGA 291 >4X8F-A nrPDB Length = 309 Score = 148 bits (372), Expect = 5e-36, Method: Composition-based stats. Identities = 61/291 (20%), Positives = 106/291 (36%), Gaps = 27/291 (9%) Query: 72 FKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYE- 130 + GG N A + F C+G D FG ++ ++ + Sbjct: 34 RNYQVIPGGKGANQAVAAARM----QADVGFIACVGDDSFGINIRESFKLDGINTAGVKL 89 Query: 131 QNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTV 190 Q PTG ++ + + A AN + E + + AR + L Sbjct: 90 QPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAI--EPDLAAIRDARYLLMQ---LET 144 Query: 191 SPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQ 250 + +LK A+ A LN AP +E +++ VD++ NETEA Sbjct: 145 PLDGILKAAQEAKTAKTNVILN-PAPA-----RELPDELLKCVDLITPNETEAEVLTGIT 198 Query: 251 GFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIID 310 ++ ++ A ++ K VI T G ++ P + D Sbjct: 199 VYDDSSAQQAADA------LHCKGIEIVIITLGSKGVWLSQNGRGQRIPGF---VVKATD 249 Query: 311 TNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGC--TFPEKPD 359 T AGD F G ++ L+ + PL I+ H AA++ + R G + P + + Sbjct: 250 TTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAE 300 >2QHP-A nrPDB Length = 296 Score = 134 bits (338), Expect = 4e-32, Method: Composition-based stats. Identities = 57/283 (20%), Positives = 106/283 (37%), Gaps = 21/283 (7%) Query: 79 GGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGT 138 GG+ N A + Q + +G D+ G+ + + + E+ + PTGT Sbjct: 24 GGAPAN---FAYHVSQFGFD-SRVVSAVGNDELGDEIMEVFKEKQLKNQ-IERVDYPTGT 78 Query: 139 CAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESV--- 195 + + + D + L +A + VS ++ Sbjct: 79 VQVTLDDEGVP-CYEIKEGVAWDNIPFTDELKRLALNTRAVCFGSLAQRNEVSRATINRF 137 Query: 196 LKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETK 255 L ++F +NL F + KE L + +IL N+ E T +R G+ Sbjct: 138 LDTMPDIDGQLKIFDINLRQDF---YTKEVLRESFKRCNILKINDEELVTISRMFGYPGI 194 Query: 256 DIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAG 315 D+++ K L K N K +I T G + + V + + + DT GAG Sbjct: 195 DLQD--KCWILLAKYNLK---MLILTCGINGSYVFTPGV---VSFQETPKVPVADTVGAG 246 Query: 316 DAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKP 358 D+F F + +++ K + E + ++ + ++G PE P Sbjct: 247 DSFTAAFCASILNGKSVPEAHKLAVEVSAYVCTQSGA-MPELP 288 >3LHX-A nrPDB Length = 319 Score = 122 bits (306), Expect = 2e-28, Method: Composition-based stats. Identities = 53/300 (17%), Positives = 104/300 (34%), Gaps = 22/300 (7%) Query: 69 VKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHY 128 K V+ GG T N+ + + +G D F + + +VD Sbjct: 19 EKGADVKRGFGGDTLNTSVYIARQVDPAALTVHYVTALGTDSFSQQMLDAWHGENVDTSL 78 Query: 129 YEQNEQP-TGTCAA-CITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGF 186 ++ E G + G R+ A + Y++G Sbjct: 79 TQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLASEQSAAICEELANFDYLYLSGI 138 Query: 187 FLTV----SPESVLKVARYAAENNRVFTL-NLSAPFI---SQFFKEALMDVMPYVDILFG 238 L + S E +L + R N P + + ++ ++ DI F Sbjct: 139 SLAILSPTSREKLLSLLRECRAKGGKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFL 198 Query: 239 NETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVA-AENDVTA 297 + +Q +D+ + + ++ + V+ +G D +V+ A + Sbjct: 199 TLDDEDALWGQQ--PVEDV---------IARTHNAGVKEVVVKRGADSCLVSIAGEALVD 247 Query: 298 FPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEK 357 P + +E++IDT AGD+F G+L+ ++ + GH AS +I+ G P + Sbjct: 248 VPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGSAENAAKRGHLTASTVIQYRGAIIPRE 307 >1TYY-A nrPDB Length = 339 Score = 119 bits (299), Expect = 2e-27, Method: Composition-based stats. Identities = 60/313 (19%), Positives = 105/313 (33%), Gaps = 42/313 (13%) Query: 67 ELVKKFKVEYH--AGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHV 124 +LV + + Y GG++ N V + + + F GC+G D G L++ D V Sbjct: 36 DLVPEKQNSYLKCPGGASAN---VGVCVARLGGE-CGFIGCLGDDDAGRFLRQVFQDNGV 91 Query: 125 DAHYYEQNEQPTGTCAA--CITGGNRSL-VANLAAANCYKKEKHLDLERNWVLVEKARVY 181 D + + T G RS A+ Y + L + + Sbjct: 92 DVTFLRLDADLTSAVLIVNLTADGERSFTYLVHPGADTYVSPQDLPP------FRQYEWF 145 Query: 182 YIAGFFLTVSP--ESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYV----DI 235 Y + LT P E+ L+ AR E +++ + + +++ I Sbjct: 146 YFSSIGLTDRPAREACLEGARRMREAGGYVLFDVNLRSKMWGNTDEIPELIARSAALASI 205 Query: 236 LFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDV 295 + E + ++ + L T I + G D ++ Sbjct: 206 CKVSADELCQLSG-----ASHWQDARYYLRDL------GCDTTIISLGADGALLITAEGE 254 Query: 296 TAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKP-----LTECIRAGHYAASVIIRRT 350 FP + +++DT GAGDAFVGG L L L E I + ++ + Sbjct: 255 FHFPA---PRVDVVDTTGAGDAFVGGLLFTLSRANCWDHALLAEAISNANACGAMAVTAK 311 Query: 351 GC--TFPEKPDFH 361 G P + Sbjct: 312 GAMTALPFPDQLN 324 >3GBU-A nrPDB Length = 313 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 67/317 (21%), Positives = 118/317 (37%), Gaps = 41/317 (12%) Query: 54 QILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGE 113 ++L + E D L E H GG+ N VA + + K ++ +G D FGE Sbjct: 9 ELLIDLISVEEGD-LKDVRLFEKHPGGAPAN---VAVGVSRLGVK-SSLISKVGNDPFGE 63 Query: 114 ILKRKAADAHVDAHYYEQNEQP-TGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNW 172 L + + +VD ++E+ TG + G + S + A + NW Sbjct: 64 YLIEELSKENVDTRGIVKDEKKHTGIVFVQLKGASPSFLLYDDVAYFNMTLNDI----NW 119 Query: 173 VLVEKARVYYIAGFFLTVSP--ESVLKVARYAAENNRV-FTLNLSAPFISQFFKEA---L 226 +VE+A++ L +P E+V+KV + ++ + F +NL +E L Sbjct: 120 DIVEEAKIVNFGSVILARNPSRETVMKVIKKIKGSSLIAFDVNLRLDLWRGQEEEMIKVL 179 Query: 227 MDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDD 286 + + DI+ +E E V K T G Sbjct: 180 EESIKLADIVKASEEEVLYLEN-------------------QGVEVKGSMLTAITLGPKG 220 Query: 287 TIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQL--VSDKPLTECIRAGHYAAS 344 + V P + N +DT GAGDAF+ L + + L + + + A+ Sbjct: 221 FRLIKNETVVDVPSYNVNP---LDTTGAGDAFMAALLVGILKLKGLDLLKLGKFANLVAA 277 Query: 345 VIIRRTGC-TFPEKPDF 360 + ++ G + P K + Sbjct: 278 LSTQKRGAWSTPRKDEL 294 >3KD6-A nrPDB Length = 313 Score = 113 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 53/279 (18%), Positives = 96/279 (34%), Gaps = 36/279 (12%) Query: 82 TQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQ-NEQPTGTCA 140 +S +A + G +G D FG+ ++D + + T A Sbjct: 28 GGSSTYIALSASYFTDEPIRMVGVVGSD-FGKEHFDLLHAKNIDTRGIQVIEDGKTFRWA 86 Query: 141 A---CITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLK 197 +L L + ++ + + PE LK Sbjct: 87 GRYHYDMNTRDTLDTQLNVFAEFD-------PHVPQYYRDSKFVCLG----NIDPELQLK 135 Query: 198 VARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDI 257 V + V ++ F + E L V+ VD+ N++EA + + Sbjct: 136 VLDQIDDPKLVVCDTMN--FWIEGKPEELKKVLARVDVFIVNDSEARLLSGD-------- 185 Query: 258 KEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDA 317 + K A+ + ++ K T+I +G ++ +N + A P E I D GAGD Sbjct: 186 PNLVKTARIIREMGPK---TLIIKKGEHGALLFTDNGIFAAPAF--PLESIYDPTGAGDT 240 Query: 318 FVGGFLSQL-----VSDKPLTECIRAGHYAASVIIRRTG 351 F GGF+ L S+ + + + G AS + + G Sbjct: 241 FAGGFIGHLARCGNTSEAEMRKAVLYGSAMASFCVEQFG 279 >2NWH-A nrPDB Length = 317 Score = 112 bits (279), Expect = 3e-25, Method: Composition-based stats. Identities = 60/279 (21%), Positives = 104/279 (37%), Gaps = 27/279 (9%) Query: 78 AGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTG 137 AGG N+ + L + + G D GE++ A A V+ + ++ T Sbjct: 38 AGGGGFNAAR---NLSRLGFEV-RIIAPRGGDVTGEVVAEAARQAGVEDTPFTFLDRRTP 93 Query: 138 TCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFL---TVSPES 194 + A + ++ A L R + + F L + ++ Sbjct: 94 SYTAILERDGNLVI-----ALADMDLYKLFTPRRLKVRAVREAIIASDFLLCDANLPEDT 148 Query: 195 VLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFET 254 + + A + +P + K AL D+ DILF NE EA E Sbjct: 149 LTALGLIARACEKPLAAIAISPAKAVKLKAALGDI----DILFMNEAEARALTGETAENV 204 Query: 255 KDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGA 314 +D I +KA V ++ V+ G + I+ P L + E+ D GA Sbjct: 205 RDWPNILRKAGLSGGVVTRGASEVVAFNGTEKAIL--------HPPLIR---EVKDVTGA 253 Query: 315 GDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCT 353 GDA G+L+ + K + E +R G AA++ ++ + T Sbjct: 254 GDAMASGYLAAIAEGKTIREALRQGAAAAAITVQSSFAT 292 >2QCV-A nrPDB Length = 332 Score = 110 bits (275), Expect = 9e-25, Method: Composition-based stats. Identities = 62/344 (18%), Positives = 120/344 (34%), Gaps = 54/344 (15%) Query: 21 SENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDE-LVKKFKVEYHAG 79 E L +G +D++AV ++ + + + G Sbjct: 10 REFDLIAIGRACIDLNAV-------------------------EYNRPMEETMTFSKYVG 44 Query: 80 GSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQP--TG 137 GS N + + L A F G I D+ G ++ VD +++ TG Sbjct: 45 GSPANIVIGSSKL----GLKAGFIGKIADDQHGRFIESYMRGVGVDTSNLVVDQEGHKTG 100 Query: 138 TCAACITGGNR--SLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSP--E 193 I L+ A+ Y + E N + ++++ ++G L+ SP E Sbjct: 101 LAFTEIKSPEECSILMYRQDVADLYLSPE----EVNEAYIRRSKLLLVSGTALSKSPSRE 156 Query: 194 SVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYV----DILFGNETEAATFARE 249 +VLK R A N+ L S E V DI+ G E Sbjct: 157 AVLKAIRLAKRNDVKVVFELDYRPYSWETPEETAVYYSLVAEQSDIVIGTREEFDVLENR 216 Query: 250 QGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEII 309 + + + I + P++ ++ G + + + + +++ Sbjct: 217 T-EKGDNDETIRYLFKHSPEL-------IVIKHGVEGSFAYTKAG--EAYRGYAYKTKVL 266 Query: 310 DTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCT 353 T GAGD++ FL L+S K + ++ G +AS+++ + + Sbjct: 267 KTFGAGDSYASAFLYALISGKGIETALKYGSASASIVVSKHSSS 310 >5EYN-A nrPDB Length = 323 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 55/301 (18%), Positives = 104/301 (34%), Gaps = 41/301 (13%) Query: 78 AGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTG 137 GG+ N VA + + ++A FFG +G D FG +++ D VD + + Sbjct: 43 PGGAPAN---VAVAIARLSGRSA-FFGRVGNDPFGRFMQQTLTDEQVDCQHLHFDPVHRT 98 Query: 138 TCAACITG--GNRSL-VANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPE- 193 + G RS +A+ + + + +K ++ L P Sbjct: 99 STVVVDLDEHGERSFTFMVKPSADQFLQLSDIPS------FQKGEWLHVCSIALANQPSR 152 Query: 194 -SVLKVARYAAENNRVFTLNLSAPFIS----QFFKEALMDVMPYVDILFGNETEAATFAR 248 S E + + + Q + +M + D++ +E E Sbjct: 153 SSTFAAIAQMKEVGGYVSFDPNLREEVWSEPQELQATVMRAVGLADVVKFSEEELQFLTG 212 Query: 249 EQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEI 308 T+ I+E + V+ T G +VA N ++ + Sbjct: 213 -----TQSIEEGLQAIADFQ------IPLVVVTLGAKGALVATPNSQQ---IVSGKAVKP 258 Query: 309 IDTNGAGDAFVGGFLSQLV------SDKPLTECIRAGHYAASVIIRRTGC--TFPEKPDF 360 IDT GAGDAFVGG L +L + + + ++ + ++ + G P + Sbjct: 259 IDTTGAGDAFVGGLLYRLSVAQDWHNQATILDAVKWANGCGALATTQKGAMTALPNQAAL 318 Query: 361 H 361 + Sbjct: 319 Y 319 >2VAR-A nrPDB Length = 313 Score = 108 bits (270), Expect = 3e-24, Method: Composition-based stats. Identities = 52/287 (18%), Positives = 100/287 (34%), Gaps = 32/287 (11%) Query: 75 EYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQ 134 E H GS N H + + +G D+FG+ + + +D + + + + Sbjct: 29 EKHVAGSELNFCIAVV----RNHLSCSLIARVGNDEFGKNIIEYSRAQGIDTSHIKVDNE 84 Query: 135 P-TGTCAAC----ITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLT 189 TG I + + +A + + N V +R+ + G L Sbjct: 85 SFTGIYFIQRGYPIPMKSELVYYRKGSAGSRLSPEDI----NENYVRNSRLVHSTGITLA 140 Query: 190 VS---PESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDI--LFGNETEAA 244 +S E+V+K A + + + KE ++ ++ DI L + + Sbjct: 141 ISDNAKEAVIKAFELAKSRSLDTNIRPKLWSSLEKAKETILSILKKYDIEVLITDPDDTK 200 Query: 245 TFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQN 304 + D E +K + L + +++ G I +N Sbjct: 201 IL-----LDVTDPDEAYRKYKEL------GVKVLLYKLGSKGAIAYKDNVKAFKDAYKVP 249 Query: 305 QEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 E D GAGDA G F+S + K + + G A++++I G Sbjct: 250 VE---DPTGAGDAMAGTFVSLYLQGKDIEYSLAHGIAASTLVITVRG 293 >4DU5-A nrPDB Length = 336 Score = 100 bits (249), Expect = 9e-22, Method: Composition-based stats. Identities = 63/330 (19%), Positives = 110/330 (33%), Gaps = 36/330 (10%) Query: 44 LDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFF 103 LD + +L D+ E + VA L + K + Sbjct: 27 LDVITFGEAMMLLVADRP-------GPLEHAEAFHKRTAGAETNVAIGLARLGLKVG-WA 78 Query: 104 GCIGIDKFGEILKRKAADAHVD-AHYYEQNEQPTGTCA-ACITGGNRSLVANLAAANCYK 161 +G D G L A +D +H Q TG +T G+ V + Sbjct: 79 SRLGTDSMGRYLLAAMAAEGIDCSHVVCDATQKTGFQFKGKVTDGSDPPVEYHRKGSAAS 138 Query: 162 KEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARY------AAENNRVFTLNLSA 215 D++ W+L AR + G F +S + L AR AA + F NL Sbjct: 139 HMGVADIDEAWLL--SARHLHATGVFPAIS-ATTLPAARKTMDLMRAAGRSVSFDPNLRP 195 Query: 216 P--FISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSK 273 + ++A+ D+ D + E E + +A+ + L Sbjct: 196 TLWATPELMRDAINDLATRADWVLPGMEEGRFLTGE-----TTPEGVARFYRQL------ 244 Query: 274 RQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLT 333 + V+ G + E E++DT GAGD F G +S L+ + Sbjct: 245 GAKLVVVKLGAEGAYFDGEAGSGRVAGF--PVAEVVDTVGAGDGFAVGVISALLDGLGVP 302 Query: 334 ECIRAGHYAASVIIRRTGCT--FPEKPDFH 361 E ++ G + + ++ G + P + + + Sbjct: 303 EAVKRGAWIGARAVQVLGDSEGLPTRAELN 332 >3IQ0-A nrPDB Length = 330 Score = 100 bits (248), Expect = 1e-21, Method: Composition-based stats. Identities = 52/260 (20%), Positives = 94/260 (36%), Gaps = 26/260 (10%) Query: 100 ATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNE-QPTGTCAACI-TGGNRSLVANLAAA 157 C+G D FG+I + A VD + TG+ G+R + N+ A Sbjct: 54 CGIISCVGNDGFGDINIHRLAADGVDIRGISVLPLEATGSAFVTYHNSGDRDFIFNIKNA 113 Query: 158 NC-YKKEKHLDLERNWVLVEKARVYYI--AGFFLTVSPESVLKVARYAAENNRV--FTLN 212 C +H+D +++ ++I + F ++V K N V F N Sbjct: 114 ACGKLSAQHVD----ENILKDCTHFHIMGSSLFSFHMVDAVKKAVTIVKANGGVISFDPN 169 Query: 213 LSAPFIS-QFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVN 271 + + ++AL V+ DI +E E + E +A+ Sbjct: 170 IRKEMLDIPEMRDALHFVLELTDIYMPSEGEVLLLSPHSTPE-----------RAIAGFL 218 Query: 272 SKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKP 331 + + VI +G + N+ F V EE +D GAGD F G +++ Sbjct: 219 EEGVKEVIVKRGNQGASYYSANE--QFHVESYPVEE-VDPTGAGDCFGGAWIACRQLGFD 275 Query: 332 LTECIRAGHYAASVIIRRTG 351 ++ + ++ + R G Sbjct: 276 AHRALQYANACGALAVTRRG 295 >4WJM-A nrPDB Length = 312 Score = 94.6 bits (233), Expect = 6e-20, Method: Composition-based stats. Identities = 59/295 (20%), Positives = 102/295 (34%), Gaps = 36/295 (12%) Query: 77 HAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPT 136 AGGS N+ A L + FF I D FG++L+ A ++VD + + +PT Sbjct: 33 FAGGSVFNT---AIALGRLGVPTG-FFSGISSDFFGDVLRDTLARSNVDYSFAAISNRPT 88 Query: 137 GTCAA-CITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESV 195 + G R + A + + + E++ Sbjct: 89 TLAFVRLVDGQARYAFYDENTAGRMLSRNDMPYVDETISAMLFGCISLISEPCGSVYETL 148 Query: 196 LKVARYAAENNRVFTLNLSAPFISQFFKEA--LMDVMPYVDILFGNETEAATFAREQGFE 253 L AR A N+ A I+ + ++ DI+ ++ + F E Sbjct: 149 L--AREAPNRVMFLDPNIRANLITVRKTHLTRMKRMIALADIVKLSDEDLDWFG-----E 201 Query: 254 TKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNG 313 EIA + L + V+ T+G + + P + +++DT G Sbjct: 202 KGSHDEIAAEWLKLGP------KLVVITKGAHGAVAYTNHATVPVP---GVKVDVVDTVG 252 Query: 314 AGDAFVGGFLSQL-------------VSDKPLTECIRAGHYAASVIIRRTGCTFP 355 AGD G L+ L +S+ + + G AA+V + R G P Sbjct: 253 AGDTVNAGILASLHSQGLLTKDALANLSEDQIHSAVALGVRAAAVTVSRAGANPP 307 >6CW5-A nrPDB Length = 332 Score = 91.9 bits (226), Expect = 4e-19, Method: Composition-based stats. Identities = 55/306 (17%), Positives = 92/306 (30%), Gaps = 28/306 (9%) Query: 67 ELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDA 126 E + + AGG N G IG D G +K A V Sbjct: 37 ETISSTGLTKRAGGKGANQAFAVA----RAGGQVELDGAIGDD--GIWVKEMLESAGVGT 90 Query: 127 HYYE-QNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAG 185 + ++ TG + + A AN Y A ++ Sbjct: 91 DKLKIVKDEVTGRAVIQSAADGENSIVLHAGANYYLPSPTP-------TTSLATYTHLL- 142 Query: 186 FFLTVSPESVLKVARYAAENNRVFT-LNLSAPFISQFFKEALMDVMPYVDILFGNETE-- 242 V S L A +++ T + +P ++ ++ L NE E Sbjct: 143 VQNEVPLSSTLAYLTAAGQSSPPLTSVFNPSPMLTPAQLREFP--WKHLSWLIVNEGELG 200 Query: 243 ----AATFAREQGFETKDIKEIAKKAQALP---KVNSKRQRTVIFTQGRDDTIVAAENDV 295 A + G +D + A L + +I T G + Sbjct: 201 DLLLAFGSSANPGEAKEDELQAKASAGILELHENDYFSKNVGIICTLGAKGILCYEPGKE 260 Query: 296 TAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFP 355 + + Q + DT GAGD F G F++ L+S K L + ++ A + + G Sbjct: 261 VGYLPAAKLQNPVKDTTGAGDCFAGYFVAGLMSGKSLQDALKTCLVACGICVENEGA-ME 319 Query: 356 EKPDFH 361 P + Sbjct: 320 SVPTLN 325 >1WYE-A nrPDB Length = 311 Score = 89.5 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 54/288 (18%), Positives = 99/288 (34%), Gaps = 36/288 (12%) Query: 75 EYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQ 134 E H GS N ++ Q +G D+FG VD + + + Sbjct: 29 EKHVAGSEANY--CVAFIKQ--GNECGIIAKVGDDEFGYNAIEWLRGQGVDVSHMKIDPS 84 Query: 135 -PTGTCAAC----ITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLT 189 PTG + + S+ +A + +D E V+ A + + +G L Sbjct: 85 APTGIFFIQRHYPVPLKSESIYYRKGSAGSKLSPEDVDEE----YVKSADLVHSSGITLA 140 Query: 190 VS---PESVLKVARYAAENNRVFTLNLSAPF-ISQFFKEALMDVMP--YVDILFGNETEA 243 +S E+V K A +NR F N+ ++ K ++ ++ ++ L + ++ Sbjct: 141 ISSTAKEAVYKAFEIA--SNRSFDTNIRLKLWSAEEAKREILKLLSKFHLKFLITDTDDS 198 Query: 244 ATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQ 303 E D + AK ++ ++ G IV + Sbjct: 199 KIILGES-----DPDKAAKAFSDYAEI-------IVMKLGPKGAIVYYDGKKYYSSGYQV 246 Query: 304 NQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 E D GAGDA G FLS + + + A+++ + G Sbjct: 247 PVE---DVTGAGDALGGTFLSLYYKGFEMEKALDYAIVASTLNVMIRG 291 >3PL2-A nrPDB Length = 319 Score = 88.4 bits (217), Expect = 5e-18, Method: Composition-based stats. Identities = 48/260 (18%), Positives = 88/260 (33%), Gaps = 21/260 (8%) Query: 100 ATFFGCIGIDKFGEILKRKAADAHVDAHYYEQN---EQPTGTCAACITGGNRSLVANLAA 156 + +G D FGE L + VD Y + + P C Sbjct: 58 SALLSRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPK 117 Query: 157 ANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARY-AAENNRVFTLNLSA 215 A + D+ + V + + GF S + ++ A + +F L+ Sbjct: 118 APD-LNIESADVSLDDVREADILWFTLTGFSEEPSRGTHREILTTRANRRHTIFDLDYRP 176 Query: 216 PF--ISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSK 273 F + + + + + GN+ E E E A +A + Sbjct: 177 MFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGE------TEPERAGRALL-----ER 225 Query: 274 RQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLT 333 I QG + +++ P ++I+ GAGDAF G L+S+ PL Sbjct: 226 GVELAIVKQGPKGVMAMTKDETVEVPPFF---VDVINGLGAGDAFGGALCHGLLSEWPLE 282 Query: 334 ECIRAGHYAASVIIRRTGCT 353 + +R + A +++ R C+ Sbjct: 283 KVLRFANTAGALVASRLECS 302 >3KZH-A nrPDB Length = 328 Score = 85.7 bits (210), Expect = 3e-17, Method: Composition-based stats. Identities = 46/284 (16%), Positives = 97/284 (34%), Gaps = 22/284 (7%) Query: 74 VEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNE 133 V+ GG +N +A+ + + F +G D+ G+ + + E Sbjct: 37 VKISFGGVCRN---IAENMARVGVNT-NFMSILGNDEHGKSIVEHSKKIGYHMDDSMVIE 92 Query: 134 QPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPE 193 + I N +V+ +A ++ + E A + + E Sbjct: 93 GGSTPTYLAILDENGEMVSAIADMKSIGAMNTDFIDSKREIFENAEYTVLDSDNPEIM-E 151 Query: 194 SVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFE 253 +LK + F L+ + + + K + D + N EA A GF Sbjct: 152 YLLKNFKDKTN----FILDPVSAEKASWVKHLIKDFHT----IKPNRHEAEILA---GFP 200 Query: 254 TKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNG 313 D ++ K + + K+ V + D ND + + + ++ + G Sbjct: 201 ITDTDDLIKASNYFLGLGIKK---VFISLDADGIFY---NDGVSCGKIKATEVDVKNVTG 254 Query: 314 AGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEK 357 AGD+FV G ++ P+ + ++ +++ I P+ Sbjct: 255 AGDSFVAGLGYGYMNKMPIEDIVKFAMTMSNITISHEETIHPDM 298 >2AFB-A nrPDB Length = 351 Score = 85.3 bits (209), Expect = 4e-17, Method: Composition-based stats. Identities = 57/306 (18%), Positives = 105/306 (34%), Gaps = 29/306 (9%) Query: 56 LAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEIL 115 L+ HK +F F V Y GG+ N VA +L Q A F + + G+ Sbjct: 25 LSPPDHKRIFQT--DSFDVTY--GGAEAN---VAAFLAQMGLD-AYFVTKLPNNPLGDAA 76 Query: 116 KRKAADAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLV 175 V Y + G I R A+ E + ++ Sbjct: 77 AGHLRKFGVKTDYIARGGNRIGIYFLEIGASQRPSKVVYDRAHSAISEAKREDFDWEKIL 136 Query: 176 EKARVYYIAGFFLTVSPESVL---KVARYAAENNRVFTLNLSAPF---ISQFFKEALMDV 229 + AR ++ +G + E L + A E + +L+ + ++ ++ Sbjct: 137 DGARWFHFSGITPPLGKELPLILEDALKVANEKGVTVSCDLNYRARLWTKEEAQKVMIPF 196 Query: 230 MPYVDILFGNETEAATFAR--EQGFETKDIKEIAKKAQALPKVNSKRQ--RTVIFTQGRD 285 M YVD+L NE + +G + K K + + + +++ +TV T Sbjct: 197 MEYVDVLIANEEDIEKVLGISVEGLDLKTGKLNREAYAKIAEEVTRKYNFKTVGITLRES 256 Query: 286 DTIVAAENDVTAFPVLDQNQ--------EEIIDTNGAGDAFVGGFLSQLVSDKPLTECIR 337 ++A + + V + Q I+D GAGD+F G + + + Sbjct: 257 ---ISATVNYWSVMVFENGQPHFSNRYEIHIVDRVGAGDSFAGALIYGSLMGFDSQKKAE 313 Query: 338 AGHYAA 343 A+ Sbjct: 314 FAAAAS 319 >2ABQ-A nrPDB Length = 306 Score = 83.8 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 48/276 (17%), Positives = 87/276 (31%), Gaps = 26/276 (9%) Query: 78 AGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTG 137 GG N +V + L E G G ++ + + E Sbjct: 35 PGGKGINVSRVLKRLGHETKALGFLGG-----FTGAYVRNALEKEEIGLSFIEVEGDT-- 87 Query: 138 TCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESV-L 196 I G + + A KKE L +EK V +AG P+++ Sbjct: 88 RINVKIKGKQETELN--GTAPLIKKEHVQALLEQLTELEKGDVLVLAGSVPQAMPQTIYR 145 Query: 197 KVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKD 256 + + A E ++ S + + + N E + K Sbjct: 146 SMTQIAKERGAFVAVDTSGEALHEVLAAKP-------SFIKPNHHELSELVS------KP 192 Query: 257 IKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGD 316 I I + ++ + +++ + D + A+ + V E+ ++ GAGD Sbjct: 193 IASIEDAIPHVQRLIGEGIESILVSFAGDGALFASAEGMFHVNVPSG---EVRNSVGAGD 249 Query: 317 AFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGC 352 + V GFL+ L K L + + A S G Sbjct: 250 SVVAGFLAALQEGKSLEDAVPFAVAAGSATAFSDGF 285 >4E69-A nrPDB Length = 328 Score = 83.4 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 61/305 (20%), Positives = 100/305 (32%), Gaps = 28/305 (9%) Query: 67 ELVKKFKVEYHAGGSTQNSMKVAQWLIQE-PHKAATFFGCIGIDKFGEILKRKAADAHVD 125 EL + G ++ A +L + P ++F IG D + ++ + A +D Sbjct: 35 ELAPADLPGTYRLGFAGDTFNTAWYLARLRPESRISYFSAIGDDALSQQMRAAMSAAGID 94 Query: 126 AHYYEQNEQPT-GTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIA 184 T G + G RS +E D + + +A V Y + Sbjct: 95 GGGLRVIPGRTVGLYLITLEQGERSFAYWRG--QSAARELAGDADALAAAMARADVVYFS 152 Query: 185 GFFLTV----SPESVLKVARYAAENNRVFTLNLSA-PFISQFFKEALMDVMPY---VDIL 236 G L + ++L+ A R + + P + E +M DI Sbjct: 153 GITLAILDQCGRATLLRALAQARATGRTIAFDPNLRPRLWAGTGEMTETIMQGAAVSDIA 212 Query: 237 FGN-ETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDV 295 + E EAA F T D + R+V+ G + Sbjct: 213 LPSFEDEAAWFGDAGPDATAD------------RYARAGVRSVVVKNGPHAVHFLQDGRR 260 Query: 296 TAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFP 355 PV Q DT AGD+F G L +++ +PL I A A +++ G Sbjct: 261 GRVPVPPVAQVV--DTTAAGDSFNAGLLDSVLAGQPLETAIAAAAALAGQVVQGKGALV- 317 Query: 356 EKPDF 360 E P Sbjct: 318 EVPSL 322 >3B1N-A nrPDB Length = 326 Score = 83.4 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 52/298 (17%), Positives = 84/298 (28%), Gaps = 35/298 (11%) Query: 55 ILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEI 114 IL + H LV + GG N + + A G +G + Sbjct: 25 ILPDQVHLINLSFLVPT--MRREFGGCAGN----IAYALNLLGGDARMMGTLGAVD-AQP 77 Query: 115 LKRKAADAHVDAHYYEQNEQPTGTCAACITG-GNRSLVANLAAANCYKKEKHLDLERNWV 173 + + Y A T N + A A H Sbjct: 78 YLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNH-------- 129 Query: 174 LVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYV 233 +A+ +A + +++ A+ F + F L + Sbjct: 130 -AGEAKDIKLAIVGPDG-FQGMVQHTEELAQAGVPFIFDPGQGLPL-FDGATLRRSIELA 186 Query: 234 DILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAEN 293 + N+ EA + G+ EIA + QAL I T+G + + Sbjct: 187 TYIAVNDYEAKLVCDKTGWSED---EIASRVQAL-----------IITRGEHGATIRHRD 232 Query: 294 DVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 P + E +ID G GDAF GG L + R ++ I G Sbjct: 233 GTEQIPAV--RAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQG 288 >3NCA-A nrPDB Length = 313 Score = 81.8 bits (200), Expect = 4e-16, Method: Composition-based stats. Identities = 44/277 (15%), Positives = 89/277 (32%), Gaps = 25/277 (9%) Query: 79 GGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDA---HYYEQNEQP 135 GG+ NS V L F G + + L VD + + + P Sbjct: 55 GGNASNSCTVLSLL----GAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTP 110 Query: 136 TGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESV 195 + C + GNR++V + + ++ + + + +I G + + + Sbjct: 111 SSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVD-----LTQFKWIHIEGRNASEQVKML 165 Query: 196 LKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETK 255 ++ A + + + +E L + Y D++F ++ A + Sbjct: 166 QRI--DAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLG------FQ 217 Query: 256 DIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAG 315 +E + R+ V+ ++ A D ++DT GAG Sbjct: 218 SAEEALR-----GLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAG 272 Query: 316 DAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGC 352 D F + L + + E +R G A G Sbjct: 273 DTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGF 309 >2HW1-A nrPDB Length = 298 Score = 81.1 bits (198), Expect = 7e-16, Method: Composition-based stats. Identities = 42/277 (15%), Positives = 86/277 (31%), Gaps = 25/277 (9%) Query: 79 GGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHY--YEQNEQ-P 135 GG+ NS V L F G + + + VD Y ++ P Sbjct: 40 GGNASNSCTVLSLL----GAPCAFMGSMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVP 95 Query: 136 TGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESV 195 T G+R+++ + ++ + + + +I G + + + Sbjct: 96 IATVIINEASGSRTILYYDRSLPDVSATDFEKVD-----LTQFKWIHIEGRNASEQVKML 150 Query: 196 LKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETK 255 ++ A + + + +E L + Y D++F ++ A + Sbjct: 151 QRI--DAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLG------FQ 202 Query: 256 DIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAG 315 +E + R+ V+ ++ A D ++DT GAG Sbjct: 203 SAEEALR-----GLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAG 257 Query: 316 DAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGC 352 D F + L + + E +R G A G Sbjct: 258 DTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGF 294 >3I3Y-A nrPDB Length = 299 Score = 76.8 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 51/287 (17%), Positives = 91/287 (31%), Gaps = 48/287 (16%) Query: 79 GGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGT 138 GG N A L + + G D G ++++ + + Q + T Sbjct: 39 GGKGANQ---AIILSRCGIET-RLIAATGNDSNGAWIRQQIKNEPLMLLPDGHFNQHSDT 94 Query: 139 CAACIT-GGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLK 197 + G+ +++ AAA+ + ++ + V + F L + Sbjct: 95 SIILNSADGDNAIITTTAAADTFSLDEMI--PHMADAVAGDILLQQGNFSLDKT----RA 148 Query: 198 VARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDI 257 + +YA N S + P +DI NE+EA Sbjct: 149 LFQYARSRGMTTVFNPS------PVNPDFCHLWPLIDIAVVNESEAELL----------- 191 Query: 258 KEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDA 317 +T++ TQG + E P + E +DT GAGD Sbjct: 192 -------------QPYGVKTLVITQGAAGAWLVQEGQRQFCPAV---PAEALDTTGAGDT 235 Query: 318 FVGGFLS-QLVSD-KPLTECIRAGHYAASVIIRRTGC--TFPEKPDF 360 F+ L+ L+ P + AA++ + R G FP + Sbjct: 236 FLAVMLASALLRGVAPDALALAHASRAAAITVSRRGTLSAFPGSREL 282 >3LJS-A nrPDB Length = 338 Score = 76.4 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 58/328 (17%), Positives = 99/328 (30%), Gaps = 40/328 (12%) Query: 48 SLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIG 107 SLK E L LVKK + VA + + A F G +G Sbjct: 2 SLKKTILCFGEALIDMLAQPLVKKGMPRAFLQCAGGAPANVAVAVARLGG-AVQFVGMLG 60 Query: 108 IDKFGEILKRKAADAHVDAHYYEQNEQPTGTCAACITG--GNRSLVANLA-AANCYKKEK 164 D FG+ L A+A V + A G RS AA+ + + Sbjct: 61 SDMFGDFLFDSFAEAGVVTDGIVRTSTAKTALAFVALDAHGERSFSFYRPPAADLLFRVE 120 Query: 165 HLDLERNWVLVEKARVYYIAGFFLTVS--PESVLKVARYAAENNRVFTLNLSAPFISQFF 222 H A +++ +T + E + R A + + +L+ + Sbjct: 121 HFQDAS----FSDALIFHACSNSMTDADIAEVTFEGMRRAQAAGAIVSFDLNFRPMLWPN 176 Query: 223 KEA----LMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTV 278 E L + D++ + E A A + ++ R + + Sbjct: 177 GENPASRLWKGLSLADVVKLSSEELDYLANTL---------AADANAVIQQLWQGRAQLL 227 Query: 279 IFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSD--------- 329 + T P + ++ D+N AGDAFVGG L Sbjct: 228 LVTDAAGPVHWYTRTAGGEVPTF---RVQVQDSNAAGDAFVGGMLYTFAQQFDDAAALID 284 Query: 330 -----KPLTECIRAGHYAASVIIRRTGC 352 + + +R ++ + R G Sbjct: 285 FCHDPESIVSTLRFAAAVGALAVTRQGA 312 >6C9R-A nrPDB Length = 337 Score = 76.1 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 55/320 (17%), Positives = 108/320 (33%), Gaps = 33/320 (10%) Query: 35 ISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQ 94 ++ + D L ++ + ++Q+L E HK LV + H GG N +A + Sbjct: 18 VTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVD--DLVMHRGGVAGN---MAFAIGV 72 Query: 95 EPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTCAACITGGN--RSLVA 152 + A G G D + V+ + +E C T + + Sbjct: 73 LGGEVA-LVGAAGADF--ADYRDWLKARGVNCDHVLISETAHTARFTCTTDVDMAQIASF 129 Query: 153 NLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLN 212 A + + + L + K + I PE++ + F + Sbjct: 130 YPGAMSEARN---IKLADVVSAIGKPELVIIGA----NDPEAMFLHTEECRKLGLAFAAD 182 Query: 213 LSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNS 272 S +++ E + ++ LF N+ E + G+ D+ + +++ Sbjct: 183 PSQ-QLARLSGEEIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADV---------MAQIDL 232 Query: 273 KRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPL 332 + + T G + + T V + D G GDAF GFL+ + L Sbjct: 233 R-----VTTLGPKGVDLVEPDGTT-IHVGVVPETSQTDPTGVGDAFRAGFLTGRSAGLGL 286 Query: 333 TECIRAGHYAASVIIRRTGC 352 + G A +++ TG Sbjct: 287 ERSAQLGSLVAVLVLESTGT 306 >3N1C-A nrPDB Length = 309 Score = 75.7 bits (184), Expect = 3e-14, Method: Composition-based stats. Identities = 57/285 (20%), Positives = 101/285 (35%), Gaps = 25/285 (8%) Query: 78 AGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTG 137 GG N VA+ + A F G GE L AD +V E + Sbjct: 37 PGGGGIN---VARAIAHLGGSATAIFPAGG--ATGEHLVSLLADENVPVATVEAKDWTRQ 91 Query: 138 TCAACITGGNRSLVANLAAANCYKKEKHLD-LERNWVLVEKARVYYIAGFFLT-VSPESV 195 + + A E LE + +E + I+G V E + Sbjct: 92 NLHVHVEASGEQYRFVMPGA--ALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKL 149 Query: 196 LKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETK 255 ++ A + ++ S +S + ++++ N+ E + + + Sbjct: 150 TQLISAAQKQGIRCIVDSSGEALSAAL------AIGNIELVKPNQKELSALVNRELTQPD 203 Query: 256 DIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTI-VAAENDVTAFPVLDQNQEEIIDTNGA 314 D+++ A++ VNS + + V+ + G + V +EN + P ++Q T GA Sbjct: 204 DVRKAAQEI-----VNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQS----TVGA 254 Query: 315 GDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPD 359 GD+ VG +L + L E +R G A S G D Sbjct: 255 GDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDD 299 >3JUL-A nrPDB Length = 320 Score = 74.1 bits (180), Expect = 9e-14, Method: Composition-based stats. Identities = 55/310 (17%), Positives = 112/310 (36%), Gaps = 30/310 (9%) Query: 49 LKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGI 108 L P L + + + + K E+ GG + V L + K G G Sbjct: 9 LNPAIDRLLFIRGELEKRKTNRVIKTEFDCGGKGLHVSGV---LSKFGIKNEAL-GIAGS 64 Query: 109 DKFGEILKRKAADAHVDAHYYEQNEQPTGTCAACITG--GNRSLVANLAAANCYKKEKHL 166 D ++ + H++ + + T C ++ +++ + +L Sbjct: 65 DNLDKLYA-ILKEKHINHDFLVEAGTSTRECFVVLSDDTNGSTMIPEAGFTVSQTNKDNL 123 Query: 167 DLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEAL 226 L++ V+K + IAG + P L + + L ++ A+ Sbjct: 124 -LKQIAKKVKKEDMVVIAG---SPPPHYTLSDFKELLRTVKATGAFLGCDNSGEYLNLAV 179 Query: 227 MDVMPYVDILFGNETE-AATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRD 285 VD + NE E A + ++I+ +A+K L + + G Sbjct: 180 E---MGVDFIKPNEDEVIAILDEKTNSLEENIRTLAEKIPYL-----------VVSLGAK 225 Query: 286 DTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGH-YAAS 344 +I A + + + + GAGD FVG F++ L + P+TE ++ +AS Sbjct: 226 GSICAHNGKLYQV---IPPKVQERNDTGAGDVFVGAFIAGLAMNMPITETLKVATGCSAS 282 Query: 345 VIIRRTGCTF 354 ++++ +F Sbjct: 283 KVMQQDSSSF 292 >4GM6-A nrPDB Length = 351 Score = 73.7 bits (179), Expect = 1e-13, Method: Composition-based stats. Identities = 51/299 (17%), Positives = 97/299 (32%), Gaps = 34/299 (11%) Query: 74 VEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNE 133 ++ H GG+ N VA L + H + + G++ VD + + Sbjct: 51 LDIHIGGAEAN---VAVNLSKLGHPT-RIATVVPANPIGKMAVEHLWRHQVDTAFVVEAG 106 Query: 134 QPTGTCAA----------CITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYI 183 GT + S A + + E L++ RV ++ Sbjct: 107 DRLGTYYLESGTALKAPSVVYDRQHSSFARHKSMDWDLSE----------LLKGIRVLHV 156 Query: 184 AGFFLTVSP---ESVLKVARYAAENNRVFTLNLSAPF---ISQFFKEALMDVMPYVDILF 237 +G + +S E V+K+ R A N + +++ + K A ++P VD Sbjct: 157 SGITIALSTFWLEMVVKIIREAKRNGIKISFDMNYRAKLWELEAAKRAYQQLLPLVDYCS 216 Query: 238 GNETEAATFAREQGFETKDIKEIAKKA-QALPKVNSKRQRTVIFTQGRDDTIVAAENDVT 296 + +A F T + + K +KR + + Sbjct: 217 AGQMDAVAFFEISSETTDYYQAMHDKYPNIELFYATKRT---VISASHHLLQGHLWTQGE 273 Query: 297 AFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFP 355 + + I+D G GDA+ L ++S+ E ++ AA + G P Sbjct: 274 CWESEEYAIYPIVDRVGGGDAYTAAVLHGILSEWRPDETVKFATAAAGLKHSIHGDINP 332 >2RBC-A nrPDB Length = 343 Score = 72.2 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 47/276 (17%), Positives = 82/276 (29%), Gaps = 31/276 (11%) Query: 86 MKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGT--CAACI 143 A + + A+ +G +G D+ G + R +++ +D Sbjct: 69 ASSAAYAVHRMGGRASLWGAVGDDETGTRILRDLSESGIDTSGMTVAPGARSALSTIIID 128 Query: 144 TGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVS-PESVLKVARYA 202 G R +V L + + V PE L V A Sbjct: 129 NRGERLIV----------PFYDHRLHEKKRACTPEDIALFDAVLVDVRWPELALDVLTVA 178 Query: 203 AENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAK 262 + L+ + E L + P + +E A + +K++ Sbjct: 179 RALGKPAILDGDVAPV-----ETLEGLAPAATHIVFSEPAATRLTGL-----ETVKDM-- 226 Query: 263 KAQALPKVNSKRQRTVI-FTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGG 321 LP ++++ +T I T G +D T Q E +DT AGD F G Sbjct: 227 ----LPVLHARYPQTFIAVTAGPAGCWWTEADDPT-VHFQTTMQVEAVDTLAAGDIFHGT 281 Query: 322 FLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEK 357 F + +R AA++ G Sbjct: 282 FALAMAEGMQSRAAVRLSSVAAALKCTVFGGRIGAP 317 >2AWD-A nrPDB Length = 323 Score = 72.2 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 47/279 (16%), Positives = 90/279 (32%), Gaps = 22/279 (7%) Query: 66 DELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVD 125 D + + +V GG N +V L + G G + + A++ Sbjct: 25 DTVNRTSQVTKTPGGKGLNVTRVIHDLGGDVIATGVLGG-----FHGAFIANELKKANIP 79 Query: 126 AHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNW-VLVEKARVYYIA 184 + E+ + A G + L A E+ + N+ L+++A + I+ Sbjct: 80 QAFTSIKEETRDSIAILHEGNQTEI---LEAGPTVSPEEISNFLENFDQLIKQAEIVTIS 136 Query: 185 GFFLTVSP-ESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEA 243 G P + ++ + A L+ S + Q + + + N E Sbjct: 137 GSLAKGLPSDFYQELVQKAHAQEVKVLLDTSGDSLRQVLQGPWKPYL-----IKPNLEEL 191 Query: 244 ATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQ 303 + E +A AL K ++ + G+D I + Sbjct: 192 EGLLGQDFSE----NPLAAVQTALTKPMFAGIEWIVISLGKDGAIAKHHDQFYRV---KI 244 Query: 304 NQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYA 342 + + G+GDA + G L D P E ++ G A Sbjct: 245 PTIQAKNPVGSGDATIAGLAYGLAKDAPAAELLKWGMAA 283 >4E84-A nrPDB Length = 352 Score = 69.5 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 58/358 (16%), Positives = 112/358 (31%), Gaps = 31/358 (8%) Query: 5 DEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKEL 64 D P + L + L E V VV LD+Y D+I E + Sbjct: 25 DIPTTENLYFQGMNTLREVVPVPREQLARSRVLVVGDVMLDRYWFGNVDRISPEAPVPVV 84 Query: 65 FDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHV 124 + ++ G N + A L A +G D+ GE + + V Sbjct: 85 HVQRQEERL------GGAANVARNAVTL----GGQAGLLCVVGCDEPGERIVELLGSSGV 134 Query: 125 DAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIA 184 H PT + + L + A + + L R VL+ + V ++ Sbjct: 135 TPHLERDPALPTTIKLRVLARQQQLLRVDFEAMPTH-EVLLAGLARFDVLLPQHDVVLMS 193 Query: 185 GFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAA 244 + V + A + ++ +++ ++ N E Sbjct: 194 DYA-KGGLTHVTTMIEKARAAGKAVLVDPKGDDWARY---------RGASLITPNRAELR 243 Query: 245 TFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQN 304 + E +A+ ++ T+ + + + P L + Sbjct: 244 EVVGQWKSEDD------LRARVANLRAELDIDALLLTRSEEGMTLFSAGGELHAPALAR- 296 Query: 305 QEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG-CTFPEKPDFH 361 E+ D +GAGD + + L + PL + + + AA +++ + G T FH Sbjct: 297 --EVFDVSGAGDTVIATVATMLGAGVPLVDAVVLANRAAGIVVGKLGTATVDYDELFH 352 >3KTN-A nrPDB Length = 346 Score = 69.1 bits (167), Expect = 3e-12, Method: Composition-based stats. Identities = 50/324 (15%), Positives = 108/324 (33%), Gaps = 57/324 (17%) Query: 44 LDKYSLKPNDQILAEDKHKELFDELVKKFKVEYH--AGGSTQNSMKVA-QWLIQEPHKAA 100 L + +LA H +L L+ K AG + + ++ QW+ ++ Sbjct: 29 LRMNFVGTGVNLLANLAHFQLETALITKLPANRLGEAGKAALRKLGISDQWVGEKGDHIG 88 Query: 101 TFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCY 160 +FF +G G +T NR +A Sbjct: 89 SFFAEMGY----------------------------GIRPTQVTYQNR-----HQSAFGI 115 Query: 161 KKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLN------LS 214 + K D E V+ + I+ + ++ L +A+ A + + L+ Sbjct: 116 SEAKDYDFEAFLAEVDMVHICGISLSLTEKTRDAALILAQKAHAYQKKVCFDFNYRPSLN 175 Query: 215 APFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKR 274 + F ++ ++PY DI+FG+ + +D++ A++ + + + S+ Sbjct: 176 TANSALFMRQQYERILPYCDIVFGSRRDLVEL--LGFIPREDLEGEAQETELIQRFMSQY 233 Query: 275 QRTVIFTQGRDDT--------IVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQL 326 R + + +N+ ++ +D GAGDA+ G L Sbjct: 234 NLEWFAGTTRSHSQNQNYLSGYLYTQNEYQQ---SEKRPLLNLDRIGAGDAYAAGILYGY 290 Query: 327 VSDKPLTECIRAG--HYAASVIIR 348 + L + + + + I+ Sbjct: 291 SQNWSLEKAVTFATVNGVLAHTIQ 314 >3BF5-A nrPDB Length = 306 Score = 68.7 bits (166), Expect = 4e-12, Method: Composition-based stats. Identities = 48/278 (17%), Positives = 92/278 (33%), Gaps = 51/278 (18%) Query: 72 FKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQ 131 + GG+ N VAQ + P + +G+ E L ++ + E+ Sbjct: 49 KDLRPRFGGTAGNFAIVAQKF-RIPF---DLYSAVGMKTHREYLA-MIESMGINTGHVEK 103 Query: 132 NEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVS 191 E +G T G + + A + L ++ + + + Sbjct: 104 FEDESGPICYIATDGKKQVSFMHQGAMAAWAPQ---------LADEYEYVHFS------T 148 Query: 192 PESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDV--MPYVDILFGNETEAATFARE 249 + L +A+ + + I ++ K+ L + Y+ I N+ E F Sbjct: 149 GPNYLDMAKSIRSK----IIFDPSQEIHKYSKDELKKFHEISYMSIF--NDHEYRVFREM 202 Query: 250 QGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEII 309 G + PKV + I T G + + + FP + + Sbjct: 203 TGL-------------SSPKVTT------IVTNGERGSSLFMDGKKYDFPAIPSSG---- 239 Query: 310 DTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVII 347 DT GAGD+F G L + + + + + G A +I Sbjct: 240 DTVGAGDSFRAGLYLALYNRRSIEKGMIYGTIIAHHVI 277 >2JG5-A nrPDB Length = 306 Score = 67.2 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 46/278 (16%), Positives = 88/278 (31%), Gaps = 26/278 (9%) Query: 66 DELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVD 125 D L + AGG N +V + L E G G+ + ++ + Sbjct: 23 DGLNRATATYKFAGGKGINVSRVLKTLDVESTALGFAGG-----FPGKFIIDTLNNSAIQ 77 Query: 126 AHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAG 185 +++ E + + T TG + A + L + + +AG Sbjct: 78 SNFIEVD-EDTRINVKLKTGQETEINAP---GPHITSTQFEQLLQQIKNTTSEDIVIVAG 133 Query: 186 FFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILF-GNETEAA 244 + P A T A + KE V+PY + N+ E Sbjct: 134 SVPSSIPSD-------AYAQIAQITAQTGAKLVVDAEKELAESVLPYHPLFIKPNKDELE 186 Query: 245 TFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQN 304 ++ K + L K ++VI + G D I + Sbjct: 187 V---MFNTTVNSDADVIKYGRLLVD---KGAQSVIVSLGGDGAIYIDKEISIKA---VNP 237 Query: 305 QEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYA 342 Q ++++T G+GD+ V G ++ + S + + + Sbjct: 238 QGKVVNTVGSGDSTVAGMVAGIASGLSIEKAFQQAVAC 275 >3GO6-A nrPDB Length = 310 Score = 64.5 bits (155), Expect = 7e-11, Method: Composition-based stats. Identities = 47/282 (16%), Positives = 76/282 (26%), Gaps = 49/282 (17%) Query: 74 VEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNE 133 + GG N A F G G D L+ V Sbjct: 51 LTRTPGGKGANQAVAAA----RAGAQVQFSGAFGDDPAAAQLRAHLRANAVGLDRTVTVP 106 Query: 134 QPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPE 193 P+GT + + V AN + + VL+ + + P Sbjct: 107 GPSGTAIIVVDASAENTVLVAPGANAHLTPVPSAVANCDVLLTQLEI-----------PV 155 Query: 194 SVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFE 253 + A AA++ + ++P + +L D+ D++ NE EA Sbjct: 156 ATALAAARAAQSADAVVMVNASPAGQD--RSSLQDLAAIADVVIANEHEA---------- 203 Query: 254 TKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNG 313 D + T G + V P +DT G Sbjct: 204 -NDWPSPPTHF--------------VITLGVRGARYVGADGVFEVPAPTVTP---VDTAG 245 Query: 314 AGDAFVGGFLSQLVS--DKPLT--ECIRAGHYAASVIIRRTG 351 AGD F G + P +R A ++ +G Sbjct: 246 AGDVFAGVLAANWPRNPGSPAERLRALRRACAAGALATLVSG 287 >2AJR-A nrPDB Length = 331 Score = 64.1 bits (154), Expect = 8e-11, Method: Composition-based stats. Identities = 57/310 (18%), Positives = 96/310 (30%), Gaps = 26/310 (8%) Query: 52 NDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKF 111 + +I ED + K + GG N + +A + P A F G G Sbjct: 24 DREIFIEDFQVNRLYRINDLSKTQMSPGGKGIN-VSIALSKLGVPSVATGFVG--GY--M 78 Query: 112 GEILKRKAADAH--VDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLE 169 G+IL + + ++ + N + + + L Sbjct: 79 GKILVEELRKISKLITTNFVYVEGETRENIEIIDEKNKTITAINFPGPDVTDMDVNHFLR 138 Query: 170 RNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDV 229 R + + K I+G E + A VF P + + E Sbjct: 139 RYKMTLSKVDCVVISGSIPPGVNEGICNELVRLARERGVFVFVEQTPRLLERIYEGPE-- 196 Query: 230 MPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIV 289 F N + F D+K + K+ K Q +V+ + ++D + Sbjct: 197 -------FPNVVKPDLRGNHASFLGVDLKTFDDYVKLAEKLAEKSQVSVVSYEVKNDIVA 249 Query: 290 AAENDVTAFPVLDQNQEEIIDTN---GAGDAFVGGFLSQLVS-DKPLTECIRAGHYAASV 345 E V +E IDT+ GAGDA+V G + + E + G +A Sbjct: 250 TREG------VWLIRSKEEIDTSHLLGAGDAYVAGMVYYFIKHGANFLEMAKFGFASALA 303 Query: 346 IIRRTGCTFP 355 RR P Sbjct: 304 ATRRKEKYMP 313 >2Q5R-A nrPDB Length = 330 Score = 57.2 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 52/292 (17%), Positives = 104/292 (35%), Gaps = 25/292 (8%) Query: 66 DELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVD 125 D++ + +V AGG N +V + EP A+ F G + G+ + +K A + Sbjct: 43 DDVNRVQEVSKTAGGKGLNVTRVLAQVG-EPVLASGFIG----GELGQFIAKKLDHADIK 97 Query: 126 AHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAG 185 +Y + T C A + G ++ + +E ++ L+EK I+G Sbjct: 98 HAFYNIKGE-TRNCIAILHEGQQTEILEQGP-EIDNQEAAGFIKHFEQLLEKVEAVAISG 155 Query: 186 FFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVM--PYV-DILFGNETE 242 L YA R N P I L V+ PY ++ N +E Sbjct: 156 SLPKG-----LNQDYYAQIIER--CQNKGVPVILDCSGATLQTVLENPYKPTVIKPNISE 208 Query: 243 AATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLD 302 + + E K+A + P + +I + G F ++ Sbjct: 209 ---LYQLLNQPLDESLESLKQAVSQPLF--EGIEWIIVSLGAQGAFAKHN---HTFYRVN 260 Query: 303 QNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTF 354 +++ G+GD+ V G S +++ + + ++ + + + + Sbjct: 261 IPTISVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGY 312 >4S1M-A nrPDB Length = 287 Score = 51.4 bits (121), Expect = 6e-07, Method: Composition-based stats. Identities = 36/181 (19%), Positives = 65/181 (35%), Gaps = 17/181 (9%) Query: 181 YYIAGFFLTVS--PESVLKVARYAAENNRVFTLNLSAPFISQFFK--------EALMDVM 230 + + G+F + E++ +V R +N +V+ L P + K +++ +++ Sbjct: 78 FLVTGYFPSSDLVYETINRVKRI-KDNKKVY--FLCDPILGDNGKMYTKSEVQDSMKELI 134 Query: 231 PYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVA 290 Y DI+ N TE + G E + E K L + +G D ++ Sbjct: 135 KYADIITPNATE---LSFLTGLEVNSVSEAIKACHILHEQGIPVILVTSIKEGNDIILLC 191 Query: 291 AENDVTAFPVLDQNQEEII-DTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRR 349 + D I D G GD LS ++ PL + I+R Sbjct: 192 SFKDTLNNKNFTIKIPRIEGDFTGVGDTLTYILLSWIIKGIPLEHAVNRAISTLQTILRN 251 Query: 350 T 350 T Sbjct: 252 T 252 >2I5B-A nrPDB Length = 271 Score = 47.6 bits (111), Expect = 9e-06, Method: Composition-based stats. Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 16/144 (11%) Query: 216 PFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFET-KDIKEIAKKAQALPKVNSKR 274 P +Q +E L P ++ N EA+ + +T D+ E AKK AL Sbjct: 121 PEHAQALREQLA---PLATVITPNLFEASQLSGMDELKTVDDMIEAAKKIHAL------G 171 Query: 275 QRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDT---NGAGDAFVGGFLSQLVSDKP 331 + V+ T G A + + + + E+IDT +GAG F ++L Sbjct: 172 AQYVVITGGGKLKHEKAVDVLYDGETAEVLESEMIDTPYTHGAGCTFSAAVTAELAKGAE 231 Query: 332 LTECIRAGHYAASVIIRRTGCTFP 355 + E I + A I +FP Sbjct: 232 VKEAI---YAAKEFITAAIKESFP 252 >5YSQ-A nrPDB Length = 286 Score = 46.8 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 43/286 (15%), Positives = 82/286 (28%), Gaps = 35/286 (12%) Query: 80 GSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFG--EILKRKAADAHVDAHYYEQNEQPTG 137 G + V + + G I G + K V + ++ G Sbjct: 6 GHVSKDVNVVDGKREIAYGGGVVMGAITSSLLGVKTKVITKCTREDVSKFSFLRDN---G 62 Query: 138 TCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLK 197 + + + N ++ +E L + ++ + +I G + ++P + Sbjct: 63 VEVVFLKSPRTTSIENRYGSDPDTRESFLISAADP--FTESDLAFIEGEAVHINPLWYGE 120 Query: 198 VARYAAENNRVFTLNLSAPF-----------ISQFFKEALMDVMPYVDILFGNETEAATF 246 R + LSA + E + Y+D+ + EA T Sbjct: 121 FPEDLIPVLRRKVMFLSADAQGFVRVPENEKLVYRDWEMKEKYLKYLDLFKVDSREAETL 180 Query: 247 AREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQE 306 T D++E + ++ +I IV N F Sbjct: 181 TG-----TNDLRESCRIIRSFGAK-------IILATHASGVIVFDGN----FYEASFRSW 224 Query: 307 EIIDTNGAGDAFVGGFLSQLVSDK-PLTECIRAGHYAASVIIRRTG 351 + G GD FL V K + + + SV +R G Sbjct: 225 SLEGRTGRGDTCTAAFLVGFVFKKMSIEKATKFAAAVTSVKMRHPG 270 >2DDM-A nrPDB Length = 283 Score = 43.7 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 43/132 (32%), Gaps = 20/132 (15%) Query: 215 APFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKR 274 P + + +++ L+ + + N E G +D+ A++L K Sbjct: 138 KPDLPEAYRQYLLPLAQG---ITPNIFELEILT---GKNCRDLDSAIAAAKSLLSDTLK- 190 Query: 275 QRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEII-------DTNGAGDAFVGGFLSQLV 327 + EN V+ + +I D G GD F +S L+ Sbjct: 191 ---WVVVTSASG---NEENQEMQVVVVTADSVNVISHSRVKTDLKGTGDLFCAQLISGLL 244 Query: 328 SDKPLTECIRAG 339 K LT+ + Sbjct: 245 KGKALTDAVHRA 256 >3MBJ-A nrPDB Length = 291 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 40/243 (16%), Positives = 76/243 (31%), Gaps = 25/243 (10%) Query: 124 VDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYI 183 + + Q G +T ++ A K E D L ++ + Sbjct: 41 LPTAVLSNHTQYPGFSFLDLTDEMPKII-----AEWKKLEVQFDAIYTGYLGSPRQIQIV 95 Query: 184 AGFFLT-VSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETE 242 + F P+S++ +N R++T F + KE + ++ D++ N TE Sbjct: 96 SDFIKDFRQPDSLIVADPVLGDNGRLYT-----NFDMEMVKE-MRHLITKADVITPNLTE 149 Query: 243 AATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFT------QGRDDTIVAAENDVT 296 E +E+ + + L K + VI T + ++ A Sbjct: 150 LFYLLDEPYKADSTDEELKEYLRLLSD---KGPQVVIITSVPVHDEPHKTSVYAYNRQGN 206 Query: 297 AFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPE 356 + + G GD F L+ L + A I++ TF Sbjct: 207 RYWKVTCPYLPAHYP-GTGDTFTSVITGSLMQGDSLPMALDR---ATQFILQGIRATFGY 262 Query: 357 KPD 359 + D Sbjct: 263 EYD 265 >3HYO-A nrPDB Length = 282 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 36/219 (16%), Positives = 68/219 (31%), Gaps = 8/219 (3%) Query: 124 VDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYI 183 + A Y+ PT + +G V +L+ + R + ++A + Y+ Sbjct: 27 LTAMQYDVAALPTSLLSTHTSGYGTPAVVDLSTW---LPQVFAHWTRAQLHFDQALIGYV 83 Query: 184 AGFFLTVSPESVLKVARYAAENNRVFTLNLSAPF--ISQFFKEALMDVMPYVDILFGNET 241 L + L+ + +L + Q + A+ ++ D++ N T Sbjct: 84 GSVALCQQITTYLEQQTLSLLVVDPVLGDLGQLYQGFDQDYVAAMRQLIQQADVILPNTT 143 Query: 242 EAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVL 301 EAA T D++ I QA K + T + + E + Sbjct: 144 EAALLTGAPYQVTPDLEVILPALQAQLKTGAHAVITDVQRADQIGCAWLDEAGHVQYCGA 203 Query: 302 DQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGH 340 + NG GD L PL + + Sbjct: 204 RRLPGHY---NGTGDTLAAVIAGLLGRGYPLAPTLARAN 239 >5B6A-A nrPDB Length = 288 Score = 39.1 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 36/175 (20%), Positives = 56/175 (32%), Gaps = 32/175 (18%) Query: 198 VARYAAENNRVFTLNLSAPFISQFFKE----------ALMDVMPYVDILFGNETEAATFA 247 VAR N R L L P + K L + D L N+ E +F Sbjct: 99 VARIKQANPR--ALYLCDPVMGHPEKGCIVAPEVSDFLLEEAAAVADYLCPNQLELDSFC 156 Query: 248 REQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQ----GRDD------TIVAAENDVTA 297 Q D E+A+ A + R ++ G+ + A + Sbjct: 157 DRQPNSLADCVEMARSLLA------RGPRAILVKHLNYPGKAGDTFEMLLVAADQAWHLQ 210 Query: 298 FPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGC 352 P+L ++ + G GD G FLS+L+ L A ++ T Sbjct: 211 RPLLAFPRQPV----GVGDLASGLFLSRLLLGDDLRNAFEFTGAAVHEVLLETQA 261 >5ZWB-B nrPDB Length = 296 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 42/129 (32%), Gaps = 11/129 (8%) Query: 229 VMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQ--GRDD 286 ++P L N E + G + ++E AQ+L K V+ T G Sbjct: 154 LLPQAQGLTPNVFELEMLS---GKPCRTLEEAVAAAQSLLSDTLKW---VVITSAPGESL 207 Query: 287 TIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVI 346 + + + + G GD F +S +V K LT + + Sbjct: 208 ETITVAVVTAQVVEVFAHPRVATELKGTGDLFCAELVSGIVQGKKLTTAAKDAAQRVLEV 267 Query: 347 ---IRRTGC 352 ++ GC Sbjct: 268 MTWTQQCGC 276 >1YGJ-A nrPDB Length = 312 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 36/107 (33%), Gaps = 10/107 (9%) Query: 227 MDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNS---------KRQRT 277 V+P DI+ N+ EA + ++ E+ ++ R Sbjct: 138 EKVVPVADIITPNQFEAELLTGRKIHSQEEALEVMDMLHSMGPDTVVITSSNLLSPRGSD 197 Query: 278 VIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLS 324 + G T + VT ++ ++ + + G GD F L+ Sbjct: 198 YLMALGSQRTRAPDGSVVTQRIRMEMHKVDAV-FVGTGDLFAAMLLA 243 >4JJP-A nrPDB Length = 267 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 28/170 (16%), Positives = 56/170 (32%), Gaps = 15/170 (8%) Query: 191 SPESVLKVARYAAENNRVFTLNLSAPFISQFF--------KEALMDVMPYVDILFGNETE 242 SPE +L++ + N + + + + + ++P I+ N E Sbjct: 88 SPEIILEIVENLKKYNPKYLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPE 147 Query: 243 AATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGR-DDTIVAAENDVTAFPVL 301 A + D+K + ++ L + V+ G D V F V Sbjct: 148 AEEITGIKIHNVDDMKRVGEEILQLGP------KFVLMKGGHLDGEAVDILVGKNIFKVY 201 Query: 302 DQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 351 + + +T+G G S L +TE + + I+R+ Sbjct: 202 KSERIDKKNTHGTGCTLSSAITSYLALGYEITEAVNLSKIYITEAIKRSF 251 >2F7K-A nrPDB Length = 327 Score = 37.2 bits (84), Expect = 0.013, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 41/113 (36%), Gaps = 22/113 (19%) Query: 227 MDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFT----- 281 V+P DI+ N+ EA + G + +E + + ++S TV+ T Sbjct: 153 EKVVPLADIITPNQFEAELLS---GRKIHSQEEALR---VMDMLHSMGPDTVVITSSDLP 206 Query: 282 --QGRDDTIVAAENDVTAFPVLDQNQEEI------IDT--NGAGDAFVGGFLS 324 QG + IV + P E I +D G GD F L+ Sbjct: 207 SPQGSNYLIVL-GSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLA 258 >1JXH-A nrPDB Length = 288 Score = 36.0 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 26/158 (16%), Positives = 45/158 (28%), Gaps = 19/158 (12%) Query: 215 APFISQFFKEALM-DVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSK 273 P +S E L ++P V ++ N EAA T+ +E+ + +AL + Sbjct: 136 DPLLSPSAIETLRVRLLPQVSLITPNLPEAAALLDAPHARTE--QEMLAQGRALLAMG-- 191 Query: 274 RQRTVIFTQGR-----DDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLS---- 324 V+ G + F N + +T+G G + Sbjct: 192 -CEAVLMKGGHLEDAQSPDWLFTREGEQRFSAPRVNTK---NTHGTGCTLSAALAALRPR 247 Query: 325 QLVSDKPLTECIR-AGHYAASVIIRRTGCTFPEKPDFH 361 + + E A G FH Sbjct: 248 HRSWGETVNEAKAWLSAALAQADTLEVGKGIGPVHHFH 285 >4C5N-A nrPDB Length = 276 Score = 35.2 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 21/128 (16%), Positives = 46/128 (35%), Gaps = 10/128 (7%) Query: 224 EALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQG 283 + ++P ++ N EA + I+++ K A + K + VI G Sbjct: 124 AMIKYLLPKATVVTPNLFEAGQLSGLGKLN--SIEDMKKAATI---IFDKGAQHVIIKGG 178 Query: 284 R----DDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAG 339 + D + + T + + ++ + +GAG F + L + K E + + Sbjct: 179 KALDQDKSYDLYYDGQTFYQLTTDMFQQSYN-HGAGCTFAAATTAYLANGKSPKEAVISA 237 Query: 340 HYAASVII 347 + I Sbjct: 238 KAFVASAI 245 >3ZS7-A nrPDB Length = 300 Score = 34.8 bits (78), Expect = 0.059, Method: Composition-based stats. Identities = 27/184 (14%), Positives = 57/184 (30%), Gaps = 28/184 (15%) Query: 163 EKHLDLERNWVLVEKARVYYIAGFFLTVSP----ESVLKVARYAAENNRVFTLNLSAP-- 216 ++ ++ R + R Y + G+ V LK R E + P Sbjct: 62 DELMEGVRANNFLSNYR-YILTGYINNVDIIGRIRDTLKEVRELREKEDKKLTFICDPVM 120 Query: 217 ------FISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKV 270 + + +A +++P DI+ N EA+ + + +++ A Sbjct: 121 GDDGIMYCKKEVLDAYRELVPLADIVTPNYFEASLLSGV------TVNDLSSAILAADWF 174 Query: 271 NSKRQRTVIFTQGRDDT------IVAAENDVTAFPVLDQNQEEIIDT---NGAGDAFVGG 321 ++ VI R+ + + + + V + G GD F Sbjct: 175 HNCGVAHVIIKSFREQENPTHLRFLYSVKEGSEAAVRRFSGVVPYHEGRYTGTGDVFAAC 234 Query: 322 FLSQ 325 L+ Sbjct: 235 LLAF 238 >5TRW-A nrPDB Length = 296 Score = 34.5 bits (77), Expect = 0.079, Method: Composition-based stats. Identities = 31/186 (16%), Positives = 64/186 (34%), Gaps = 25/186 (13%) Query: 182 YIAGFFLTVSPE---SVLKVARYAAENN-------RVFTLNLSAPFISQFFKEALMDVMP 231 ++G+ +PE SVL++ + N +S + +E L+ MP Sbjct: 87 VLSGYL--GTPEQAQSVLEIVKAVKAANPRAWYFCDPVMGAVSGCKVEPGIQEFLVRTMP 144 Query: 232 YV-DILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFT------QGR 284 V D + N TE R G E + ++E A ++ ++ + V+ Sbjct: 145 GVADAMAPNHTE---LQRLVGREIETLEEA---VTACRELIARGPKLVLVKHLLDRNSPA 198 Query: 285 DDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAAS 344 D + + A+ G GD F+++ + + A + Sbjct: 199 DRFNMLVVTEREAWMGQRPLYPFARQPVGVGDLTSAVFVARTLLGDSIRAAFEHTLAAVN 258 Query: 345 VIIRRT 350 +++ T Sbjct: 259 AVVKAT 264 >4XF7-A nrPDB Length = 273 Score = 34.1 bits (76), Expect = 0.093, Method: Composition-based stats. Identities = 18/113 (15%), Positives = 35/113 (30%), Gaps = 3/113 (2%) Query: 238 GNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTA 297 E + K + + Q L + + ++ + G + Sbjct: 144 PGEIQYQPIDGSFLKGVKILHADLGEYQYLQGFSPEFVDVLLLSNGPEPGKAFLHGREYT 203 Query: 298 FPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRT 350 F + +E + GAGD F+G F + RA + A + R+ Sbjct: 204 FEPVHVGVDE---STGAGDVFLGAFTGFYSQCPFVQALKRAAAFTALFLKNRS 253 >6AVO-A nrPDB Length = 199 Score = 32.5 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 19/42 (45%), Gaps = 1/42 (2%) Query: 313 GAGDAFVGGFL-SQLVSDKPLTECIRAGHYAASVIIRRTGCT 353 G+G F+ G++ + EC R A ++ + R G + Sbjct: 128 GSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSS 169 >1POI-B nrPDB Length = 260 Score = 32.1 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 29/60 (48%) Query: 176 EKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDI 235 EK + Y+A ++ T SPE VL+ + + ++ L P + + +E + ++ + Sbjct: 200 EKTKRMYLAAYYPTSSPEDVLENTGFDLDVSKAVELEAPDPAVIKLIREEIDPGQAFIQV 259 >5XGE-A nrPDB Length = 568 Score = 31.4 bits (69), Expect = 0.60, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 32/80 (40%), Gaps = 4/80 (5%) Query: 46 KYSLKPNDQIL--AEDKHKELFDELVKKFKVEYHAGGSTQNSM-KVAQWLIQEPHKAATF 102 +Y L+ + L +H +F +L + V G + + + + L+Q+ + Sbjct: 157 EYRLQIALERLERNSGRHALMFLDLDQFKLVNDTCGHAAGDELLRQVCTLLQQGLREGDT 216 Query: 103 FGCIGIDKFGEILKRKAADA 122 +G D+FG IL Sbjct: 217 LARLGGDEFG-ILLENCPAE 235 >2QEQ-A nrPDB Length = 434 Score = 31.4 bits (69), Expect = 0.65, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 34/92 (36%), Gaps = 8/92 (8%) Query: 254 TKDIKEIAKKAQALPKVNS-KRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTN 312 T DI E+ +A ++S K + I T+G I+ + VTA + + + Sbjct: 223 TTDISEMGANFKASRVIDSRKSVKPTIITEGEGRVILGEPSAVTAASAAQRRGRTGRNPS 282 Query: 313 GAGDAFVGGFLSQLVSDKPLTECIRAGHYAAS 344 AGD + G + H+ + Sbjct: 283 QAGDEYCYG-------GHTNEDDSNCAHWTEA 307 >1UB0-A nrPDB Length = 258 Score = 31.0 bits (68), Expect = 0.76, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 43/114 (37%), Gaps = 14/114 (12%) Query: 228 DVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFT----QG 283 + P D++ N EA G + +KE + A+AL + K V+ +G Sbjct: 126 RLFPLADLVTPNRLEAEAL---LGRPIRTLKEAEEAAKALLALGPK---AVLLKGGHLEG 179 Query: 284 RDDT-IVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECI 336 + ++A V F + +T+G G + L +PL E + Sbjct: 180 EEAVDLLATRGGVLRFSAPRVHTR---NTHGTGCTLSAAIAALLAKGRPLAEAV 230 >5TQI-A nrPDB Length = 294 Score = 30.6 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 20/147 (13%), Positives = 44/147 (29%), Gaps = 23/147 (15%) Query: 214 SAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSK 273 P + +F + ++ D + N TE A G + + E + L K Sbjct: 130 PEPGVEEFI---VNEMPALADGMSPNHTELQKLA---GRRIETVAEAVDACRTLIARGPK 183 Query: 274 RQRTVIFTQGRDD----------TIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFL 323 ++ D + E + P+ + + G GD F+ Sbjct: 184 ---IILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPV----GVGDLTSAIFV 236 Query: 324 SQLVSDKPLTECIRAGHYAASVIIRRT 350 ++ + + A +++ T Sbjct: 237 ARRLRGDSVRAAFEHTLAAVHAVVKAT 263 >4BHD-A nrPDB Length = 428 Score = 30.2 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 25/72 (34%) Query: 269 KVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVS 328 ++N V ++ + FP + E GA A+ G + L++ Sbjct: 145 EMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIA 204 Query: 329 DKPLTECIRAGH 340 K + +R G Sbjct: 205 GKQFQDPLREGA 216 >4QU2-A nrPDB Length = 318 Score = 30.2 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 19/48 (39%) Query: 193 ESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNE 240 E+ L+ R A + +L+ P + + E + Y D + N Sbjct: 5 EAALEAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRDWVCPNR 52 >5AHK-A nrPDB Length = 588 Score = 29.5 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 33/88 (37%), Gaps = 12/88 (13%) Query: 29 GNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKE----------LFDELVKKFKVEYHA 78 G LLDI + + +D+ L N+ + E K + + ++L K Sbjct: 180 GPVLLDIPMDIQRADIDEALL--NNPMTPEPKVQRPSIAMSDLDFIINKLQNAKKPLLLI 237 Query: 79 GGSTQNSMKVAQWLIQEPHKAATFFGCI 106 GG NS +WL Q + + + Sbjct: 238 GGGAVNSSGFQKWLEQIELRGIPYVASL 265 >5U47-A nrPDB Length = 707 Score = 29.5 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 36/88 (40%), Gaps = 19/88 (21%) Query: 18 QALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYH 77 Q L ++ G+GN + +S K ++K N+QIL F EL + Sbjct: 611 QNLVHPIVLGVGNKIEKVSVDA------KENIKANEQIL---IMTNEFTELPDMY----- 656 Query: 78 AGGSTQNSMKVAQW----LIQEPHKAAT 101 G + +N A+W + + K+ T Sbjct: 657 -GWTKKNVETFAKWKGIKITYKGGKSGT 683 >3UNF-N nrPDB Length = 199 Score = 29.1 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 313 GAGDAFVGGFL-SQLVSDKPLTECIRAGHYAASVIIRRTGCT 353 G+G +++ G++ + EC R A ++ + R G + Sbjct: 128 GSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSS 169 >1V59-A nrPDB Length = 478 Score = 28.3 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 21/33 (63%) Query: 282 QGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGA 314 + IVA ++VT FP ++ ++E+I+ + GA Sbjct: 144 LDVKNIIVATGSEVTPFPGIEIDEEKIVSSTGA 176 >3LAD-A nrPDB Length = 476 Score = 27.9 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 18/36 (50%) Query: 281 TQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGD 316 ++ I+A+ + P +Q+ I+D+ GA D Sbjct: 140 VLDTENVILASGSKPVEIPPAPVDQDVIVDSTGALD 175 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.117 0.271 Lambda K H 0.267 0.0361 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,695,118 Number of Sequences: 36641 Number of extensions: 377868 Number of successful extensions: 1444 Number of sequences better than 10.0: 90 Number of HSP's better than 10.0 without gapping: 103 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 1220 Number of HSP's gapped (non-prelim): 151 length of query: 361 length of database: 10,336,785 effective HSP length: 98 effective length of query: 263 effective length of database: 6,745,967 effective search space: 1774189321 effective search space used: 1774189321 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.5 bits)