BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P55222 (214 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2OZ6-A nrPDB 421 e-118 3KCC-A nrPDB 281 2e-76 4I0B-A nrPDB 281 2e-76 3IWZ-A nrPDB 220 4e-58 4CYD-A nrPDB 80 8e-16 3I59-A nrPDB 77 7e-15 4EV0-A nrPDB 69 1e-12 2XKO-A nrPDB 66 1e-11 3LA7-A nrPDB 66 1e-11 3B02-A nrPDB 62 3e-10 2ZCW-A nrPDB 60 8e-10 3E6B-A nrPDB 56 1e-08 3DKW-A nrPDB 49 2e-06 3H3Z-A nrPDB 47 5e-06 1ZYB-A nrPDB 47 5e-06 3E97-A nrPDB 47 9e-06 1FT9-A nrPDB 46 1e-05 6CJQ-A nrPDB 45 2e-05 5E44-A nrPDB 45 2e-05 2GAU-A nrPDB 44 6e-05 5V4S-A nrPDB 42 1e-04 4I2O-A nrPDB 41 4e-04 5KBF-A nrPDB 41 4e-04 2N7G-A nrPDB 40 6e-04 4F8A-A nrPDB 40 6e-04 5VA1-A nrPDB 40 6e-04 5K7L-A nrPDB 40 8e-04 4CHV-A nrPDB 39 0.001 2FMY-A nrPDB 39 0.001 3DV8-A nrPDB 38 0.003 5FET-A nrPDB 38 0.004 5J3U-A nrPDB 37 0.007 5DYK-A nrPDB 36 0.015 5JAX-A nrPDB 35 0.021 4Z07-A nrPDB 35 0.025 4QX5-A nrPDB 35 0.028 6BYS-B nrPDB 35 0.029 3SHR-A nrPDB 34 0.039 5JON-A nrPDB 34 0.044 6FTF-B nrPDB 33 0.066 2QCS-B nrPDB 33 0.100 4DIN-B nrPDB 33 0.11 5H3O-A nrPDB 33 0.12 2XRN-A nrPDB 32 0.20 5U6P-A nrPDB 31 0.34 3UKN-A nrPDB 30 0.61 4L11-A nrPDB 30 0.93 3J4Q-B nrPDB 28 2.3 1E3H-A nrPDB 28 2.6 2QVS-B nrPDB 28 3.0 5A4J-A nrPDB 28 3.0 6BQ8-A nrPDB 28 3.2 3NRV-A nrPDB 28 3.5 1LJ9-A nrPDB 27 4.8 6QI9-D nrPDB 27 6.5 2CQA-A nrPDB 27 7.5 2GLX-A nrPDB 27 8.4 >2OZ6-A nrPDB Length = 207 Score = 421 bits (1081), Expect = e-118, Method: Compositional matrix adjust. Identities = 206/206 (100%), Positives = 206/206 (100%) Query: 9 KLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNS 68 KLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNS Sbjct: 2 KLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNS 61 Query: 69 GDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADR 128 GDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADR Sbjct: 62 GDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADR 121 Query: 129 LRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMV 188 LRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMV Sbjct: 122 LRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMV 181 Query: 189 GRVLKSLEEQGLVHVKGKTMVVFGTR 214 GRVLKSLEEQGLVHVKGKTMVVFGTR Sbjct: 182 GRVLKSLEEQGLVHVKGKTMVVFGTR 207 >3KCC-A nrPDB Length = 260 Score = 281 bits (718), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 134/202 (66%), Positives = 168/202 (83%), Gaps = 3/202 (1%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 L+ L+HCH +Y +KST+I+ G++ ETL++I+KGSV +LI+D++G+EMI+ YLN GDF Sbjct: 62 LEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFI 121 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKT 132 GELGLFE EG QERSAWVRAK CEVAEISY KFR+L Q + +IL L +QMA RL+ T Sbjct: 122 GELGLFE-EG--QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVT 178 Query: 133 TRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVL 192 + KVG+LAFL VTGR+A+TLL+L +QPDAMTHPDGMQIKITRQEIG+IVGCSRE VGR+L Sbjct: 179 SEKVGNLAFLLVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRIL 238 Query: 193 KSLEEQGLVHVKGKTMVVFGTR 214 K LE+Q L+ GKT+VV+GTR Sbjct: 239 KMLEDQNLISAHGKTIVVYGTR 260 >4I0B-A nrPDB Length = 222 Score = 281 bits (718), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 134/202 (66%), Positives = 168/202 (83%), Gaps = 3/202 (1%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 L+ L+HCH +Y +KST+I+ G++ ETL++I+KGSV +LI+D++G+EMI+ YLN GDF Sbjct: 24 LEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFI 83 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKT 132 GELGLFE EG QERSAWVRAK CEVAEISY KFR+L Q + +IL L +QMA RL+ T Sbjct: 84 GELGLFE-EG--QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVT 140 Query: 133 TRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVL 192 + KVG+LAFLDVTGR+A+TLL+L +QPDAMT PDGMQIKITRQEIG+IVGCSRE VGR+L Sbjct: 141 SEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTLPDGMQIKITRQEIGQIVGCSRETVGRIL 200 Query: 193 KSLEEQGLVHVKGKTMVVFGTR 214 K LE+Q L+ GKT+VV+GTR Sbjct: 201 KMLEDQNLISAHGKTIVVYGTR 222 >3IWZ-A nrPDB Length = 230 Score = 220 bits (560), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 101/207 (48%), Positives = 147/207 (71%), Gaps = 8/207 (3%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 +++ LAH HRRRY ++ + GD TL+++I GSV+I+ E+DD RE+++GY SG+F Sbjct: 27 IERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYFGSGEFV 86 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQD-----SEILYTLGSQMAD 127 GE+GLF + + R +R + +CE+AEISY + ++L Q ILY +G Q++ Sbjct: 87 GEMGLFIESDT---REVILRTRTQCELAEISYERLQQLFQTSLSPDAPRILYAIGVQLSK 143 Query: 128 RLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREM 187 RL TTRK LAFLDVT R+ RTL DL ++P+AM+HP G Q++++RQE+ R+VGCSREM Sbjct: 144 RLLDTTRKASRLAFLDVTDRIVRTLHDLSKEPEAMSHPQGTQLRVSRQELARLVGCSREM 203 Query: 188 VGRVLKSLEEQGLVHVKGKTMVVFGTR 214 GRVLK L+ GL+H +GKT+V++GTR Sbjct: 204 AGRVLKKLQADGLLHARGKTVVLYGTR 230 >4CYD-A nrPDB Length = 225 Score = 79.7 bits (195), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 59/206 (28%), Positives = 99/206 (48%), Gaps = 13/206 (6%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 ++ L+ R+ +TI G+ + L+ I G V + DGRE ++ + D F Sbjct: 20 VNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARHAPDGRENLLTIMGPSDMF 79 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKT 132 GEL +F+ R++ E A ++ R I L +A RLR+T Sbjct: 80 GELSIFDP----GPRTSSAVCVTEVHAATMNSDMLRNWVADHPAIAEQLLRVLARRLRRT 135 Query: 133 TRKVGDLAFLDVTGRVARTLLDLC-----QQPDAMTHPDGMQIKITRQEIGRIVGCSREM 187 + DL F DV GRVA+TLL L Q+ A+ + +T++EI ++VG SRE Sbjct: 136 NASLADLIFTDVPGRVAKTLLQLANRFGTQEAGALR----VNHDLTQEEIAQLVGASRET 191 Query: 188 VGRVLKSLEEQGLVHVKGKTMVVFGT 213 V + L + +G + ++GK++++ T Sbjct: 192 VNKALATFAHRGWIRLEGKSVLIVDT 217 >3I59-A nrPDB Length = 249 Score = 76.6 bits (187), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 56/185 (30%), Positives = 90/185 (48%), Gaps = 11/185 (5%) Query: 30 TIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSA 89 T+ G+ + L+ II G V I DGRE ++ + D FGEL +F+ R++ Sbjct: 61 TVFAEGEPGDRLYIIISGKVKIGRRAPDGRENLLTIMGPSDMFGELSIFDP----GPRTS 116 Query: 90 WVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVA 149 E + R EI L +A RLR+T + DL F DV GRVA Sbjct: 117 SATTITEVRAVSMDRDALRSWIADRPEISEQLLRVLARRLRRTNNNLADLIFTDVPGRVA 176 Query: 150 RTLLDLCQQPDAMTHPDGMQIKI----TRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKG 205 + LL L Q+ +G +++ T++EI ++VG SRE V + L +G + ++G Sbjct: 177 KQLLQLAQR---FGTQEGGALRVTHDLTQEEIAQLVGASRETVNKALADFAHRGWIRLEG 233 Query: 206 KTMVV 210 K++++ Sbjct: 234 KSVLI 238 >4EV0-A nrPDB Length = 216 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 60/207 (28%), Positives = 98/207 (47%), Gaps = 10/207 (4%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + H + +D L++ RR Y I Y GD + L+ + G V + G+E + Sbjct: 6 LFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQERTL 65 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 L G+ FGE+ L + E ERSA A + E+ + + L ++ + + L + Sbjct: 66 ALLGPGELFGEMSLLD----EGERSASAVAVEDTELLALFREDYLALIRRLPLVAHNLAA 121 Query: 124 QMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGC 183 +A RLR+ ++ L+F + RVA LL L +Q G +I E+ + G Sbjct: 122 LLARRLREADLELDLLSFEEARNRVAYALLKLLRQ------GLGPLFQIRHHELAALAGT 175 Query: 184 SREMVGRVLKSLEEQGLVHVKGKTMVV 210 SRE V RVL +L E+G+V + T+ V Sbjct: 176 SRETVSRVLHALAEEGVVRLGPGTVEV 202 >2XKO-A nrPDB Length = 222 Score = 65.9 bits (159), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 49/185 (26%), Positives = 88/185 (47%), Gaps = 5/185 (2%) Query: 30 TIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSA 89 TI + GD E ++ ++KG+V + + G E+ + L FG L L + S++ A Sbjct: 32 TIFFPGDPAERVYLLVKGAVKLSRVYESGEEITVALLRENSVFGVLSLLTGQRSDRFYHA 91 Query: 90 WVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVA 149 V+ I + + + L ++ E+ + ++ R+ +T + LA D+ R+ Sbjct: 92 VAFTPVQLFSVPIEFMQ-KALIER-PELANVMLQGLSSRILQTEMMIETLAHRDMGSRLV 149 Query: 150 RTLLDLCQQPDAMTHPDGMQI--KITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKT 207 LL LC+ + PDG+ I K++ Q I +G +R V R+L L E L+ + K Sbjct: 150 SFLLILCRD-FGIPSPDGITIDLKLSHQAIAEAIGSTRVTVTRLLGDLRESKLIAIHKKR 208 Query: 208 MVVFG 212 + VF Sbjct: 209 ITVFN 213 >3LA7-A nrPDB Length = 243 Score = 65.9 bits (159), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 58/223 (26%), Positives = 100/223 (44%), Gaps = 26/223 (11%) Query: 8 PKLKHL----DKLLAHCHRRRYTA-----------KSTIIYAGDRCETLFFIIKGSVTIL 52 P+ H+ DK LA+ R+ T TI + GD E ++F++KG+V + Sbjct: 16 PRGSHMIVTQDKALANVFRQMATGAFPPVVETFERNKTIFFPGDPAERVYFLLKGAVKLS 75 Query: 53 IEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQ 112 + G E+ + L FG L L S++ A VE A I + + + Sbjct: 76 RVYEAGEEITVALLRENSVFGVLSLLTGNKSDRFYHAVAFTPVELLSAPIE--QVEQALK 133 Query: 113 QDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQ---PDAMTHPDGMQ 169 ++ E+ + ++ R+ +T + LA D+ R+ LL LC+ P A DG+ Sbjct: 134 ENPELSMLMLRGLSSRILQTEMMIETLAHRDMGSRLVSFLLILCRDFGVPCA----DGIT 189 Query: 170 I--KITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVV 210 I K++ Q I +G +R V R+L L E+ ++ + K + V Sbjct: 190 IDLKLSHQAIAEAIGSTRVTVTRLLGDLREKKMISIHKKKITV 232 >3B02-A nrPDB Length = 195 Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 11/179 (6%) Query: 23 RRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEG 82 +R+ K TI G+ TL+ + +G V ++ DGR + + ++ GD+FGE L EG Sbjct: 2 KRFARKETIYLRGEEARTLYRLEEGLVRVVELLPDGRLITLRHVLPGDYFGEEAL---EG 58 Query: 83 SEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFL 142 +A A E V + E D E L+ + +A ++R+ L Sbjct: 59 KAYRYTA--EAMTEAVVQGL------EPRAMDHEALHRVARNLARQMRRVQAYEAHLQTG 110 Query: 143 DVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLV 201 ++ R+AR LL L P + G+ + ++ +EI RE V +VL L +GL+ Sbjct: 111 ELRARIARYLLFLADTPLSARDRQGIYVTVSHEEIADATASIRESVSKVLADLRREGLI 169 >2ZCW-A nrPDB Length = 202 Score = 59.7 bits (143), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 47/182 (25%), Positives = 80/182 (43%), Gaps = 20/182 (10%) Query: 25 YTAKSTIIYAG-----DRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFE 79 + A I+Y G DR + +++G V + D++G + + + G FFGE LF Sbjct: 10 FKAGDVILYPGVPGPRDRA---YRVLEGLVRLEAVDEEGNALTLRLVRPGGFFGEEALF- 65 Query: 80 KEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDL 139 QER + A + + + D E+L L ++ L + R++ L Sbjct: 66 ----GQERIYFAEAATDVRLEPLP-------ENPDPELLKDLAQHLSQGLAEAYRRIERL 114 Query: 140 AFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQG 199 A + R+A LL+L + P A + +K T E+ VG RE V +V+ L +G Sbjct: 115 ATQRLKNRMAAALLELSETPLAHEEEGKVVLKATHDELAAAVGSVRETVTKVIGELAREG 174 Query: 200 LV 201 + Sbjct: 175 YI 176 >3E6B-A nrPDB Length = 250 Score = 55.8 bits (133), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 39/195 (20%), Positives = 83/195 (42%), Gaps = 16/195 (8%) Query: 23 RRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGEL----GLF 78 R + S +I G+ ++ F+++G + + I +DG E ++ Y G+L Sbjct: 35 RDFAKGSAVIMPGEEITSMIFLVEGKIKLDIIFEDGSEKLLYYAGGNSLIGKLYPTGNNI 94 Query: 79 EKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGD 138 E R+ W K R + + D ++++ + ++ R+V + Sbjct: 95 YATAMEPTRTCWFSEK-----------SLRTVFRTDEDMIFEIFKNYLTKVAYYARQVAE 143 Query: 139 LAFLDVTGRVARTLLDLC-QQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEE 197 + + T R+ R +LC Q + + + ++++ IG I G V RVL SL+ Sbjct: 144 MNTYNPTIRILRLFYELCSSQGKRVGDTYEITMPLSQKSIGEITGVHHVTVSRVLASLKR 203 Query: 198 QGLVHVKGKTMVVFG 212 + ++ K ++V+ Sbjct: 204 ENILDKKKNKIIVYN 218 >3DKW-A nrPDB Length = 227 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 42/203 (20%), Positives = 87/203 (42%), Gaps = 13/203 (6%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 L +LLA + + G+ +++I G V I +G+E I+ N + F Sbjct: 25 LQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIYRLTPEGQEKILEVTNERNTF 84 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKT 132 E +F + A +A V ++ S + Q ++ + L ++++ RL + Sbjct: 85 AEAMMFMDTPN---YVATAQAVVPSQLFRFSNKAYLRQLQDNTPLALALLAKLSTRLHQR 141 Query: 133 TRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDG----MQIKITRQEIGRIVGCSREMV 188 ++ L+ + T RV R LL L H G ++I + +Q + + E Sbjct: 142 IDEIETLSLKNATHRVVRYLLTLA------AHAPGENCRVEIPVAKQLVAGHLSIQPETF 195 Query: 189 GRVLKSLEEQGLVHVKGKTMVVF 211 R++ L ++G++H+ G+ + + Sbjct: 196 SRIMHRLGDEGIIHLDGREISIL 218 >3H3Z-A nrPDB Length = 235 Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 45/190 (23%), Positives = 74/190 (38%), Gaps = 7/190 (3%) Query: 11 KHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGD 70 +H+D LL+ R Y T+ ++ + + +I G V + G E ++ G+ Sbjct: 23 QHVDALLSQAVWRSYDRGETLFLQEEKAQAIHVVIDGWVKLFRMTPTGSEAVVSVFTRGE 82 Query: 71 FFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLR 130 FGE + SA A CEV I F L ++D EI ++ + L Sbjct: 83 SFGEAVAL--RNTPYPVSA--EAVTPCEVMHIPSPVFVSLMRRDPEICISILATTFGHLH 138 Query: 131 KTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGR 190 ++ L RVA LL+LC D T + + + I +G E + R Sbjct: 139 SLVAQLEQLKAQTGAQRVAEFLLELC---DCDTGACEVTLPYDKMLIAGRLGMKPESLSR 195 Query: 191 VLKSLEEQGL 200 L+ G+ Sbjct: 196 AFSRLKAAGV 205 >1ZYB-A nrPDB Length = 232 Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 40/191 (20%), Positives = 83/191 (43%), Gaps = 10/191 (5%) Query: 21 HRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK 80 H ++ A TII +G+ C L F++KG ++I+ + +I + + LF Sbjct: 44 HFIKHKAGETIIKSGNPCTQLCFLLKGEISIVTNAKENIYTVIEQIEAPYLIEPQSLF-- 101 Query: 81 EGSEQERSAWVRAKVECEVAEISYA-KFRELSQQDSEILYTLGSQMADRLRKTTRKVGDL 139 G ++ A E IS A +L + D L + +++R + ++ D Sbjct: 102 -GMNTNYASSYVAHTEVHTVCISKAFVLSDLFRYDIFRLNYMNI-VSNRAQNLYSRLWDE 159 Query: 140 AFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQG 199 LD+ ++ R L C++P K+ ++ R + +R + + L L++ G Sbjct: 160 PTLDLKSKIIRFFLSHCEKPQG-----EKTFKVKMDDLARCLDDTRLNISKTLNELQDNG 214 Query: 200 LVHVKGKTMVV 210 L+ + K +++ Sbjct: 215 LIELHRKEILI 225 >3E97-A nrPDB Length = 231 Score = 46.6 bits (109), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 43/187 (22%), Positives = 77/187 (41%), Gaps = 7/187 (3%) Query: 23 RRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEG 82 R + ++ E L + G V + GRE ++G + + GE + Sbjct: 32 RNFQPDELVVEQDAEGEALHLVTTGVVRVSRVSLGGRERVLGDIYAPGVVGETAVL---- 87 Query: 83 SEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAF- 141 + QERSA VRA + F + ++ +L+ L +A R+ ++ +AF Sbjct: 88 AHQERSASVRALTPVRTLMLHREHFELILRRHPRVLWNLAEMLARRVTFLNDEL--IAFG 145 Query: 142 LDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLV 201 + + +L +Q A P + + Q+I SRE V RVLK LE ++ Sbjct: 146 QNTEAALTHVFANLYRQRLAAGVPQPEVLPLGTQDIMARTSSSRETVSRVLKRLEAHNIL 205 Query: 202 HVKGKTM 208 V +++ Sbjct: 206 EVSPRSV 212 >1FT9-A nrPDB Length = 222 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 43/187 (22%), Positives = 78/187 (41%), Gaps = 14/187 (7%) Query: 22 RRRYTAKSTIIYAGDRCET-LFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK 80 R + AK +++ G+ E +F ++ G + + + ++ RE+ + YL SGD F Sbjct: 24 RSKIHAKGSLVCTGEGDENGVFVVVDGRLRVYLVGEE-REISLFYLTSGDMFC------- 75 Query: 81 EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLA 140 V A EV F + Q + + L + + L R + DL Sbjct: 76 ----MHSGCLVEATERTEVRFADIRTFEQKLQTCPSMAWGLIAILGRALTSCMRTIEDLM 131 Query: 141 FLDVTGRVARTLLDLCQQPDAMTHPDGM-QIKITRQEIGRIVGCSREMVGRVLKSLEEQG 199 F D+ R+A +D T + + T +EI ++G SR+ L SL ++G Sbjct: 132 FHDIKQRIAGFFIDHANTTGRQTQGGVIVSVDFTVEEIANLIGSSRQTTSTALNSLIKEG 191 Query: 200 LVHVKGK 206 + +G+ Sbjct: 192 YISRQGR 198 >6CJQ-A nrPDB Length = 456 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 7/102 (6%) Query: 16 LLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGEL 75 ++ H Y II AG+ ++FI +GSV +L D+ R I L+ G FFGE+ Sbjct: 332 IILHLEPVIYGPGEYIIRAGEMGSDVYFINRGSVEVLSADEKTRYAI---LSEGQFFGEM 388 Query: 76 GLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEI 117 L + R+A VRA+ C++ + F + + EI Sbjct: 389 ALILR----APRTATVRARAFCDLYRLDKETFDRILSRYPEI 426 >5E44-A nrPDB Length = 259 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 46/211 (21%), Positives = 94/211 (44%), Gaps = 7/211 (3%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIY-AGDRCETLFFIIKGSVTILIEDDDGRE 60 + I T LD+L R++ K ++ AGD + L+ I G++ + G E Sbjct: 37 LCIPFTLNDSELDQLDEIIERKKPIQKGQELFKAGDELKCLYAIRSGTIKSYTITEQGDE 96 Query: 61 MIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYT 120 I + +GD G + +E + ++ +A V EI Y +LS + ++ Sbjct: 97 QITAFHLAGDLVGFDAI-----TEAQHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQ 151 Query: 121 LGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMT-HPDGMQIKITRQEIGR 179 + M++ ++ + L+ + R+A L +L + P ++ +TR +IG Sbjct: 152 IMRLMSNEIKGDQEMILLLSKKNAEERLAAFLYNLSTRFHQRGFSPREFRLTMTRGDIGN 211 Query: 180 IVGCSREMVGRVLKSLEEQGLVHVKGKTMVV 210 +G + E + R+L ++ ++ VKGK + + Sbjct: 212 YLGLTVETISRLLGRFQKTEMLTVKGKYITI 242 >2GAU-A nrPDB Length = 232 Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 4/178 (2%) Query: 29 STIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERS 88 ST+ GD LF++ +G + IL E GR I + G FFG F +E+ S Sbjct: 42 STVFSEGDIPNNLFYLYEGKIKILREGVYGRFHISRIVKPGQFFGMRPYF----AEETCS 97 Query: 89 AWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRV 148 + A +V I L + ++ +A L R+ L V GR+ Sbjct: 98 STAIAVENSKVLAIPVEAIEALLKGNTSFCRYFLKALAKELGYAERRTVTLTQKHVRGRL 157 Query: 149 ARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGK 206 A TLL L + + I ++R+E+ + + R L + + ++ + GK Sbjct: 158 AETLLILKENFGFENDGATLSIYLSREELATLSNMTVSNAIRTLSTFVSERMLALDGK 215 >5V4S-A nrPDB Length = 465 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 7/87 (8%) Query: 30 TIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSA 89 TI G++ + L+ + +GSV IL D D + +++ L G FFGEL L + RSA Sbjct: 371 TIFRRGEKGDDLYILSEGSVDIL--DSDEKTILLS-LQEGQFFGELALV----MDAPRSA 423 Query: 90 WVRAKVECEVAEISYAKFRELSQQDSE 116 VRA CE+ +S F + ++ S+ Sbjct: 424 TVRATTTCEIYTLSKTDFDNVLKRFSQ 450 >4I2O-A nrPDB Length = 243 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 45/185 (24%), Positives = 78/185 (42%), Gaps = 13/185 (7%) Query: 32 IYAGDR-CETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFG-ELGLFEKEGSEQERSA 89 IY D E ++ ++ G+V DGR I + GD FG E G + +E Sbjct: 51 IYGEDEPAEYVYQVVTGAVRSYKLLSDGRRQIGAFHLPGDVFGLESGPSHRLAAE----- 105 Query: 90 WVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVA 149 A ++ V + + + + D ++ L + A LR + L RVA Sbjct: 106 ---AIIDTSVRLVKRSSLEKAAGIDVQVARKLWAMTAGELRHAEDHMLLLGRKTAMERVA 162 Query: 150 RTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMV 209 LL++ ++ + M + ++R++IG +G + E V R L L QG++ G + Sbjct: 163 TFLLEMDRR---LAVAGMMALPMSRRDIGDYLGLTLETVSRALSQLHTQGILGFSGARQI 219 Query: 210 VFGTR 214 V R Sbjct: 220 VLRNR 224 >5KBF-A nrPDB Length = 301 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 14/121 (11%) Query: 4 ITHTPKLKHLDKL----LAHCHRRR-YTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDG 58 ++H LK +D +A C + + Y II G+ +T F +I G+ + D Sbjct: 167 LSHVNILKDMDPYERCKVADCLKSKSYNDGEIIIKEGEEGDTFFILIDGNA---VASKDN 223 Query: 59 REMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEIL 118 + +I GD+FGEL L + + R+A ++A+ C+V + F+ L +IL Sbjct: 224 K--VIKTYTKGDYFGELALLK----NKPRAATIKAQNFCQVVYLDRKSFKRLLGPIEDIL 277 Query: 119 Y 119 + Sbjct: 278 H 278 Score = 33.9 bits (76), Expect = 0.060, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Query: 30 TIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSA 89 II GD + L+ I +G V I ++ ++ ++ L S D FGEL L +R+A Sbjct: 75 NIINEGDYGDLLYVIDQGEVEIYKTKENNKKEVLTVLKSKDVFGELALL----YNSKRAA 130 Query: 90 WVRAKVECEVAEISYAKF 107 A +C + + F Sbjct: 131 TATALTKCHLWALDRESF 148 >2N7G-A nrPDB Length = 154 Score = 40.4 bits (93), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 19/103 (18%) Query: 30 TIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGE-LGLFEKEGSEQERS 88 T+++AGD L+FI +GS+ IL D +++ L D FGE L L+ + G + + Sbjct: 58 TLVHAGDLLTALYFISRGSIEILRGD-----VVVAILGKNDIFGEPLNLYARPG---KSN 109 Query: 89 AWVRAKVECEVAEIS----------YAKFRELSQQDSEILYTL 121 VRA C++ +I Y +F + EI + L Sbjct: 110 GDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNL 152 >4F8A-A nrPDB Length = 160 Score = 40.4 bits (93), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 26/79 (32%), Positives = 45/79 (56%), Gaps = 8/79 (10%) Query: 25 YTAKSTIIY-AGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGS 83 + A +IY AG+ ++L F++ GS+ + I+DD+ ++ L GD FG+ +F KE + Sbjct: 54 HCAPGDLIYHAGESVDSLCFVVSGSLEV-IQDDE----VVAILGKGDVFGD--VFWKEAT 106 Query: 84 EQERSAWVRAKVECEVAEI 102 + A VRA C++ I Sbjct: 107 LAQSCANVRALTYCDLHVI 125 >5VA1-A nrPDB Length = 795 Score = 40.4 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 28/111 (25%) Query: 12 HLDK-LLAHCHRRRYTAK------------------STIIYAGDRCETLFFIIKGSVTIL 52 HL++ LL HC R K T+++AGD L+FI +GS+ IL Sbjct: 491 HLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEIL 550 Query: 53 IEDDDGREMIIGYLNSGDFFGE-LGLFEKEGSEQERSAWVRAKVECEVAEI 102 D +++ L D FGE L L+ + G + + VRA C++ +I Sbjct: 551 RGD-----VVVAILGKNDIFGEPLNLYARPG---KSNGDVRALTYCDLHKI 593 >5K7L-A nrPDB Length = 857 Score = 40.0 bits (92), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 23/119 (19%) Query: 31 IIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSAW 90 I +AG+ ++L F++ GS+ + I+DD+ ++ L GD FG+ +F KE + + A Sbjct: 581 IYHAGESVDSLCFVVSGSLEV-IQDDE----VVAILGKGDVFGD--VFWKEATLAQSCAN 633 Query: 91 VRAKVECEVAEIS----------YAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDL 139 VRA C++ I Y F ++ + Y L R R RK+ D+ Sbjct: 634 VRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNL------RKRIVFRKISDV 686 >4CHV-A nrPDB Length = 361 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 11/95 (11%) Query: 23 RRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEG 82 R A + I G+ + +FF+++GSV++ + L G FFGE+ L E Sbjct: 254 RTVPAGAVICRIGEPGDRMFFVVEGSVSVATPNPV-------ELGPGAFFGEMALISGE- 305 Query: 83 SEQERSAWVRAKVECEVAEISYAKFRELSQQDSEI 117 RSA V A + + A F+ L EI Sbjct: 306 ---PRSATVSAATTVSLLSLHSADFQMLCSSSPEI 337 >2FMY-A nrPDB Length = 220 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 37/190 (19%), Positives = 82/190 (43%), Gaps = 17/190 (8%) Query: 16 LLAHCHRRRYTAKSTIIYAGDRCETLFFIIK-GSVTILIEDDDGREMIIGYLNSGDFFGE 74 +L +RY+ K+ I+Y + L F++K G V + + +D +E + L +GD F Sbjct: 23 VLKEFREQRYSKKA-ILYTPNTERNLVFLVKSGRVRVYLAYED-KEFTLAILEAGDIFC- 79 Query: 75 LGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTR 134 A+++A + + F+ + + + + D L+ + Sbjct: 80 ----------THTRAFIQAMEDTTILYTDIRNFQNIVVEFPAFSLNMVKVLGDLLKNSLT 129 Query: 135 KVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIK--ITRQEIGRIVGCSREMVGRVL 192 + L F D R+A L+ + P G++++ + +EI ++G +R+ V +L Sbjct: 130 IINGLVFKDARLRLAEFLVQ-AAMDTGLKVPQGIKLELGLNTEEIALMLGTTRQTVSVLL 188 Query: 193 KSLEEQGLVH 202 ++ G++ Sbjct: 189 NDFKKMGILE 198 >3DV8-A nrPDB Length = 220 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 49/207 (23%), Positives = 90/207 (43%), Gaps = 20/207 (9%) Query: 15 KLLAHCHRRRYTAKSTIIYAGDR-CETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFG 73 KL++ ++ K TII+ G+ C L + G + I D+GRE+ + L F Sbjct: 20 KLISDNLITQHVKKGTIIHNGNMDCTGLLLVKSGQLRTYILSDEGREITLYRL----FDM 75 Query: 74 ELGLFEKEGSEQERSAWVRAKVECE----VAEISYAKFRELSQQDSEILYTLGSQMADRL 129 ++ L S RS +E E + I ++ + + + + MA R Sbjct: 76 DMCLLS--ASCIMRSIQFEVTIEAEKDTDLWIIPAEIYKGIMKDSAPVANYTNELMATRF 133 Query: 130 RKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGM-QIKITRQEIGRIVGCSREMV 188 + + + + RVA LL+ T +G ++KIT + I +G RE++ Sbjct: 134 SDVMWLIEQIMWKSLDKRVASFLLE-------ETSIEGTNELKITHETIANHLGSHREVI 186 Query: 189 GRVLKSLEEQGLVHV-KGKTMVVFGTR 214 R+L+ + +GLV + +GK ++ R Sbjct: 187 TRMLRYFQVEGLVKLSRGKITILDSKR 213 >5FET-A nrPDB Length = 847 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 9/83 (10%) Query: 20 CHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFE 79 C + + TI+ GD + LF + +G T+ I D + R LN G +FGE L Sbjct: 186 CVIQMFKPGETIVKQGDYGDVLFILKEGKATVFINDKEIR-----VLNKGSYFGERALLY 240 Query: 80 KEGSEQERSAWVRAKVECEVAEI 102 E RSA + AK A I Sbjct: 241 DE----PRSATIIAKEPTACASI 259 >5J3U-A nrPDB Length = 261 Score = 37.0 bits (84), Expect = 0.007, Method: Compositional matrix adjust. Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 9/102 (8%) Query: 11 KHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTI--LIEDDDGREMIIGYLNS 68 K L+ ++ ++ A + +I GD E L+ + G + LI DG E ++ + Sbjct: 28 KDLNTVILAMQEKKIEASTCLIREGDDGECLYIVQSGELNCSKLI---DGEERVVKVVGP 84 Query: 69 GDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFREL 110 GD FGEL L R+A V + C++ E+ F + Sbjct: 85 GDAFGELALL----YNAPRAATVTSVSACDLWELGRDTFNAI 122 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 7/93 (7%) Query: 25 YTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDFFGELGLFEKEGS 83 +T + I+ G+ + + + +GS G+ I + +GD+FGEL L + Sbjct: 164 FTDGAYIVRQGELGDVFYIVEEGSAVATKSFGPGQPPIEVKKYQAGDYFGELALI----N 219 Query: 84 EQERSAWVRAKVECEVAEISYAKFREL--SQQD 114 E+ R+A V A C+VA + F+ L S QD Sbjct: 220 EEPRAANVIAHGICKVACLERKSFKRLMGSVQD 252 >5DYK-A nrPDB Length = 853 Score = 35.8 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 9/83 (10%) Query: 20 CHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFE 79 C + + + TI+ GD + L+ + +G T+ I D++ R L G +FGE L Sbjct: 192 CVIQNFKSGETIVKQGDYGDVLYILKEGKATVYINDEEIR-----VLEKGSYFGERALLY 246 Query: 80 KEGSEQERSAWVRAKVECEVAEI 102 E RSA + AK A I Sbjct: 247 DE----PRSATIIAKEPTACASI 265 >5JAX-A nrPDB Length = 135 Score = 35.0 bits (79), Expect = 0.021, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDF 71 L KL Y II G R +T F I KG+V + ED + + + L GD+ Sbjct: 29 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDW 88 Query: 72 FGELGL 77 FGE L Sbjct: 89 FGEKAL 94 >4Z07-A nrPDB Length = 262 Score = 35.0 bits (79), Expect = 0.025, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDF 71 L KL Y II G R +T F I KG+V + ED + + + L GD+ Sbjct: 156 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDW 215 Query: 72 FGELGL 77 FGE L Sbjct: 216 FGEKAL 221 >4QX5-A nrPDB Length = 153 Score = 34.7 bits (78), Expect = 0.028, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDF 71 L KL Y II G R +T F I KG+V + ED + + + L GD+ Sbjct: 29 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDW 88 Query: 72 FGELGL 77 FGE L Sbjct: 89 FGEKAL 94 >6BYS-B nrPDB Length = 379 Score = 34.7 bits (78), Expect = 0.029, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 5/89 (5%) Query: 31 IIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDFFGELGLFEKEGSEQERSA 89 I+ G+ + F I++GS +L + E + +G L D+FGE+ L + R+A Sbjct: 280 IVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALL----MNRPRAA 335 Query: 90 WVRAKVECEVAEISYAKFRELSQQDSEIL 118 V A+ + ++ +F + S+IL Sbjct: 336 TVVARGPLKCVKLDRPRFERVLGPCSDIL 364 Score = 26.6 bits (57), Expect = 8.3, Method: Compositional matrix adjust. Identities = 20/86 (23%), Positives = 37/86 (43%), Gaps = 9/86 (10%) Query: 25 YTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSE 84 + A T+I GD + + I +G + + + ++ + G FGEL L Sbjct: 156 FIAGETVIQQGDEGDNFYVIDQGEMDVYVNNE-----WATSVGEGGSFGELALIYG---- 206 Query: 85 QERSAWVRAKVECEVAEISYAKFREL 110 R+A V+AK ++ I +R + Sbjct: 207 TPRAATVKAKTNVKLWGIDRDSYRRI 232 >3SHR-A nrPDB Length = 299 Score = 34.3 bits (77), Expect = 0.039, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDF 71 L KL Y II G R +T F I KG V + ED + + + L GD+ Sbjct: 173 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGKVNVTREDSPNEDPVFLRTLGKGDW 232 Query: 72 FGELGL 77 FGE L Sbjct: 233 FGEKAL 238 >5JON-A nrPDB Length = 517 Score = 34.3 bits (77), Expect = 0.044, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 9/105 (8%) Query: 31 IIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSAW 90 II G + ++FI G V++L + + +EM L+ G +FGE+ L + R+A Sbjct: 421 IIREGTIGKKMYFIQHGVVSVLTKGN--KEM---KLSDGSYFGEICLL----TRGRRTAS 471 Query: 91 VRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRK 135 VRA C + +S F E+ ++ + + DRL + +K Sbjct: 472 VRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKK 516 >6FTF-B nrPDB Length = 304 Score = 33.5 bits (75), Expect = 0.066, Method: Compositional matrix adjust. Identities = 16/51 (31%), Positives = 27/51 (52%) Query: 25 YTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGEL 75 ++ II+ G+ E L+ I++G+V ++ D DG + GD GEL Sbjct: 186 FSPGEYIIHYGEEGEWLYIIMEGTVEVIGRDADGEPTKVCEFTQGDHIGEL 236 >2QCS-B nrPDB Length = 291 Score = 33.1 bits (74), Expect = 0.100, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Query: 31 IIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDFFGELGLF 78 I+ G+ + F I++GS +L + E + +G L D+FGE+ L Sbjct: 191 IVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALL 239 Score = 26.6 bits (57), Expect = 8.4, Method: Compositional matrix adjust. Identities = 20/86 (23%), Positives = 37/86 (43%), Gaps = 9/86 (10%) Query: 25 YTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSE 84 + A T+I GD + + I +G + + + ++ + G FGEL L Sbjct: 67 FIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATS-----VGEGGSFGELALIYG---- 117 Query: 85 QERSAWVRAKVECEVAEISYAKFREL 110 R+A V+AK ++ I +R + Sbjct: 118 TPRAATVKAKTNVKLWGIDRDSYRRI 143 >4DIN-B nrPDB Length = 381 Score = 32.7 bits (73), Expect = 0.11, Method: Compositional matrix adjust. Identities = 22/89 (24%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Query: 31 IIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDFFGELGLFEKEGSEQERSA 89 I+ G+ + + I +G+ ++L E + +G L D+FGE+ L + R+A Sbjct: 282 IVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALL----LNRPRAA 337 Query: 90 WVRAKVECEVAEISYAKFRELSQQDSEIL 118 V A+ + ++ +F + SEIL Sbjct: 338 TVVARGPLKCVKLDRPRFERVLGPCSEIL 366 >5H3O-A nrPDB Length = 738 Score = 32.7 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 5/83 (6%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 L +L+ + ++ I GD ++ + +G + ++ DDDG+++ + L G F Sbjct: 507 LAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV--DDDGKKVFVT-LQEGSVF 563 Query: 73 GELGLFEKEGSE--QERSAWVRA 93 GEL + GS+ R+A VR+ Sbjct: 564 GELSILNIAGSKNGNRRTANVRS 586 >2XRN-A nrPDB Length = 241 Score = 32.0 bits (71), Expect = 0.20, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 4/45 (8%) Query: 163 THPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKT 207 +HP G+ + I ++VG R V R++ +LEE+ LV G Sbjct: 17 SHPHGLSLA----AIAQLVGLPRSTVQRIINALEEEFLVEALGPA 57 >5U6P-A nrPDB Length = 660 Score = 31.2 bits (69), Expect = 0.34, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 9/105 (8%) Query: 31 IIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSAW 90 II G + ++FI G ++ + +EM L G +FGE+ L K R+A Sbjct: 502 IIREGAVGKKMYFIQHGVAGVITKS--SKEM---KLTDGSYFGEICLLTK----GRRTAS 552 Query: 91 VRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRK 135 VRA C + +S F E+ ++ + + DRL + +K Sbjct: 553 VRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKK 597 >3UKN-A nrPDB Length = 212 Score = 30.4 bits (67), Expect = 0.61, Method: Compositional matrix adjust. Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 7/80 (8%) Query: 31 IIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSAW 90 +I GD + ++F+ GS+ +L ++ ++ L GD G L +++ + +A Sbjct: 109 LIRQGDALQAIYFVCSGSMEVLKDN-----TVLAILGKGDLIGSDSLTKEQVIKT--NAN 161 Query: 91 VRAKVECEVAEISYAKFREL 110 V+A C++ IS RE+ Sbjct: 162 VKALTYCDLQYISLKGLREV 181 >4L11-A nrPDB Length = 204 Score = 29.6 bits (65), Expect = 0.93, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 5/44 (11%) Query: 31 IIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGE 74 +++ GD L+FI +GS+ IL +D +++ L D FGE Sbjct: 106 LVHKGDVLTYLYFIARGSIEILKDD-----VVMAILGKDDIFGE 144 >3J4Q-B nrPDB Length = 402 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 1/47 (2%) Query: 31 IIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGL 77 +I GD + + I +G+ IL+ D+ + Y N G FGEL L Sbjct: 164 VIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGS-FGELAL 209 >1E3H-A nrPDB Length = 757 Score = 28.1 bits (61), Expect = 2.6, Method: Compositional matrix adjust. Identities = 13/60 (21%), Positives = 33/60 (55%), Gaps = 8/60 (13%) Query: 152 LLDLCQQPDAMTH--PDGMQIKITRQEIGRIVGCSREMVGRVLK------SLEEQGLVHV 203 +++ PD M+ P + +KI +IG ++G R+M+ ++ + ++E+ G +++ Sbjct: 582 MMEAIDTPDEMSPNAPRIITVKIPVDKIGEVIGPKRQMINQIQEDTGAEITIEDDGTIYI 641 >2QVS-B nrPDB Length = 310 Score = 28.1 bits (61), Expect = 3.0, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 5/80 (6%) Query: 31 IIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSAW 90 +I GD + + I +G+ IL+ D+ + Y N G FGEL L R+A Sbjct: 72 VIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGS-FGELALM----YNTPRAAT 126 Query: 91 VRAKVECEVAEISYAKFREL 110 + A E + + FR + Sbjct: 127 IIATSEGSLWGLDRVTFRRI 146 >5A4J-A nrPDB Length = 559 Score = 28.1 bits (61), Expect = 3.0, Method: Compositional matrix adjust. Identities = 24/103 (23%), Positives = 40/103 (38%), Gaps = 7/103 (6%) Query: 116 EILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQ 175 EI G + A K + +L F +V +A+T L P + P G +I + Sbjct: 457 EIYGADGVEFAPAALKEINTLEELGFKNVPVCIAKTQYSLTDDPKLLGRPTGFKINVRNV 516 Query: 176 EIGRIVGCSREMVGRVL-------KSLEEQGLVHVKGKTMVVF 211 +I G + G ++ + E+ V V GK +F Sbjct: 517 KISAGAGFVVALTGAIMTMPGLPKRPAAEKIDVDVNGKIAGLF 559 >6BQ8-A nrPDB Length = 152 Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 8/78 (10%) Query: 25 YTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGRE--MIIGYLNSGDFFGELGLFEKEG 82 Y II G+ T F + KG V + + +G + +I L G++FGE L Sbjct: 41 YDKGDYIIREGEEGSTFFILAKGKVKV-TQSTEGHDQPQLIKTLQKGEYFGEKALI---- 95 Query: 83 SEQERSAWVRAKVECEVA 100 S+ RSA + A+ E +VA Sbjct: 96 SDDVRSANIIAE-ENDVA 112 >3NRV-A nrPDB Length = 148 Score = 27.7 bits (60), Expect = 3.5, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 175 QEIGRIVGCSREMVGRVLKSLEEQGLVHVKG 205 Q+I I+G + V R +K LEE+ + V G Sbjct: 58 QKISDILGLDKAAVSRTVKKLEEKKYIEVNG 88 >1LJ9-A nrPDB Length = 144 Score = 27.3 bits (59), Expect = 4.8, Method: Compositional matrix adjust. Identities = 13/51 (25%), Positives = 24/51 (47%), Gaps = 11/51 (21%) Query: 152 LLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVH 202 L+ +C+ P I +++I ++ R R +K LEEQG ++ Sbjct: 35 LVRVCENPG-----------IIQEKIAELIKVDRTTAARAIKRLEEQGFIY 74 >6QI9-D nrPDB Length = 463 Score = 26.9 bits (58), Expect = 6.5, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 16/80 (20%) Query: 87 RSAWVRAK-----VECEVAEISY--------AKFRELSQQDSEI--LYTLGSQMADRLRK 131 RS VR K +E EV EI +K +L+ + +E+ +Y LG++M + L K Sbjct: 125 RSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTK 184 Query: 132 TTRKVGDLAFLD-VTGRVAR 150 + GD+ +D TG++++ Sbjct: 185 DKVQAGDVITIDKATGKISK 204 >2CQA-A nrPDB Length = 95 Score = 26.6 bits (57), Expect = 7.5, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 38/67 (56%), Gaps = 11/67 (16%) Query: 95 VECEVAEI--------SYAKFRELSQQDSEI--LYTLGSQMADRLRKTTRKVGDLAFLD- 143 +E EV EI + +K +L+ + +E+ +Y LG++M + L K + GD+ +D Sbjct: 14 IEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDK 73 Query: 144 VTGRVAR 150 TG++++ Sbjct: 74 ATGKISK 80 >2GLX-A nrPDB Length = 332 Score = 26.6 bits (57), Expect = 8.4, Method: Compositional matrix adjust. Identities = 10/33 (30%), Positives = 20/33 (60%) Query: 155 LCQQPDAMTHPDGMQIKITRQEIGRIVGCSREM 187 LC++P AMT D ++ + +E G ++G + + Sbjct: 90 LCEKPLAMTLEDAREMVVAAREAGVVLGTNHHL 122 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2OZ6-A nrPDB 236 4e-63 3KCC-A nrPDB 221 1e-58 4I0B-A nrPDB 220 4e-58 3IWZ-A nrPDB 181 2e-46 4CYD-A nrPDB 174 4e-44 5E44-A nrPDB 167 3e-42 3I59-A nrPDB 165 1e-41 3LA7-A nrPDB 165 2e-41 2XKO-A nrPDB 159 1e-39 3H3Z-A nrPDB 157 2e-39 3DKW-A nrPDB 152 1e-37 4EV0-A nrPDB 149 1e-36 3E6B-A nrPDB 147 3e-36 2GAU-A nrPDB 144 2e-35 1ZYB-A nrPDB 139 1e-33 3E97-A nrPDB 135 1e-32 1FT9-A nrPDB 134 4e-32 4I2O-A nrPDB 133 5e-32 2ZCW-A nrPDB 129 1e-30 3B02-A nrPDB 125 9e-30 2FMY-A nrPDB 118 2e-27 6CJQ-A nrPDB 88 2e-18 5KBF-A nrPDB 83 7e-17 5K7L-A nrPDB 81 5e-16 5V4S-A nrPDB 79 2e-15 4CHV-A nrPDB 77 4e-15 4F8A-A nrPDB 76 9e-15 5VA1-A nrPDB 74 5e-14 2N7G-A nrPDB 72 1e-13 Sequences not found previously or not previously below threshold: 2H6C-A nrPDB 136 8e-33 1O5L-A nrPDB 91 3e-19 3DV8-A nrPDB 89 1e-18 5W5B-A nrPDB 79 1e-15 4DIN-B nrPDB 67 4e-12 5J3U-A nrPDB 67 5e-12 6BYS-B nrPDB 66 1e-11 2QCS-B nrPDB 65 3e-11 3J4Q-B nrPDB 64 3e-11 2QVS-B nrPDB 62 1e-10 5JON-A nrPDB 62 2e-10 5DYK-A nrPDB 62 2e-10 3SHR-A nrPDB 61 4e-10 5H3O-A nrPDB 60 6e-10 4Z07-A nrPDB 60 6e-10 5U6P-A nrPDB 60 7e-10 5FET-A nrPDB 60 1e-09 6BQ8-A nrPDB 59 1e-09 3UKN-A nrPDB 59 1e-09 4QX5-A nrPDB 59 2e-09 4L11-A nrPDB 59 2e-09 5JAX-A nrPDB 59 2e-09 1CX4-A nrPDB 58 3e-09 4X6Q-B nrPDB 57 5e-09 6FTF-B nrPDB 57 8e-09 4ORF-A nrPDB 53 8e-08 4MGY-E nrPDB 50 5e-07 1O7F-A nrPDB 50 5e-07 4F7Z-A nrPDB 48 3e-06 4AVC-A nrPDB 45 2e-05 2D93-A nrPDB 32 0.14 5W1E-A nrPDB 32 0.16 4L5I-A nrPDB 32 0.16 2W48-A nrPDB 32 0.16 3E3M-A nrPDB 30 1.0 5TRD-A nrPDB 29 1.6 4C0Q-A nrPDB 29 1.8 1V4R-A nrPDB 29 2.0 3TGN-A nrPDB 29 2.0 5WHM-A nrPDB 29 2.1 2XRN-A nrPDB 28 3.1 5LOJ-A nrPDB 28 3.3 3F8M-A nrPDB 28 3.7 2DBB-A nrPDB 28 3.7 6J1O-A nrPDB 28 3.9 3H5O-A nrPDB 28 4.1 2B0L-A nrPDB 27 4.4 4L9V-A nrPDB 27 4.6 5E4R-A nrPDB 27 5.2 1QBJ-A nrPDB 27 5.5 4XDZ-A nrPDB 27 7.5 2UWM-A nrPDB 27 7.5 1UXV-A nrPDB 27 7.5 2L54-A nrPDB 27 7.6 2H09-A nrPDB 27 7.9 5TJJ-A nrPDB 27 8.1 4AIH-A nrPDB 27 8.4 1OSL-A nrPDB 27 8.6 >2OZ6-A nrPDB Length = 207 Score = 236 bits (603), Expect = 4e-63, Method: Composition-based stats. Identities = 206/207 (99%), Positives = 206/207 (99%) Query: 8 PKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLN 67 KLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLN Sbjct: 1 MKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLN 60 Query: 68 SGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMAD 127 SGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMAD Sbjct: 61 SGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMAD 120 Query: 128 RLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREM 187 RLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREM Sbjct: 121 RLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREM 180 Query: 188 VGRVLKSLEEQGLVHVKGKTMVVFGTR 214 VGRVLKSLEEQGLVHVKGKTMVVFGTR Sbjct: 181 VGRVLKSLEEQGLVHVKGKTMVVFGTR 207 >3KCC-A nrPDB Length = 260 Score = 221 bits (564), Expect = 1e-58, Method: Composition-based stats. Identities = 132/202 (65%), Positives = 167/202 (82%), Gaps = 3/202 (1%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 L+ L+HCH +Y +KST+I+ G++ ETL++I+KGSV +LI+D++G+EMI+ YLN GDF Sbjct: 62 LEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFI 121 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKT 132 GELGLFE+ QERSAWVRAK CEVAEISY KFR+L Q + +IL L +QMA RL+ T Sbjct: 122 GELGLFEE---GQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVT 178 Query: 133 TRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVL 192 + KVG+LAFL VTGR+A+TLL+L +QPDAMTHPDGMQIKITRQEIG+IVGCSRE VGR+L Sbjct: 179 SEKVGNLAFLLVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRIL 238 Query: 193 KSLEEQGLVHVKGKTMVVFGTR 214 K LE+Q L+ GKT+VV+GTR Sbjct: 239 KMLEDQNLISAHGKTIVVYGTR 260 >4I0B-A nrPDB Length = 222 Score = 220 bits (560), Expect = 4e-58, Method: Composition-based stats. Identities = 132/202 (65%), Positives = 167/202 (82%), Gaps = 3/202 (1%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 L+ L+HCH +Y +KST+I+ G++ ETL++I+KGSV +LI+D++G+EMI+ YLN GDF Sbjct: 24 LEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFI 83 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKT 132 GELGLFE+ QERSAWVRAK CEVAEISY KFR+L Q + +IL L +QMA RL+ T Sbjct: 84 GELGLFEE---GQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVT 140 Query: 133 TRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVL 192 + KVG+LAFLDVTGR+A+TLL+L +QPDAMT PDGMQIKITRQEIG+IVGCSRE VGR+L Sbjct: 141 SEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTLPDGMQIKITRQEIGQIVGCSRETVGRIL 200 Query: 193 KSLEEQGLVHVKGKTMVVFGTR 214 K LE+Q L+ GKT+VV+GTR Sbjct: 201 KMLEDQNLISAHGKTIVVYGTR 222 >3IWZ-A nrPDB Length = 230 Score = 181 bits (460), Expect = 2e-46, Method: Composition-based stats. Identities = 101/207 (48%), Positives = 147/207 (71%), Gaps = 8/207 (3%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 +++ LAH HRRRY ++ + GD TL+++I GSV+I+ E+DD RE+++GY SG+F Sbjct: 27 IERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYFGSGEFV 86 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQD-----SEILYTLGSQMAD 127 GE+GLF + + R +R + +CE+AEISY + ++L Q ILY +G Q++ Sbjct: 87 GEMGLFIESDT---REVILRTRTQCELAEISYERLQQLFQTSLSPDAPRILYAIGVQLSK 143 Query: 128 RLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREM 187 RL TTRK LAFLDVT R+ RTL DL ++P+AM+HP G Q++++RQE+ R+VGCSREM Sbjct: 144 RLLDTTRKASRLAFLDVTDRIVRTLHDLSKEPEAMSHPQGTQLRVSRQELARLVGCSREM 203 Query: 188 VGRVLKSLEEQGLVHVKGKTMVVFGTR 214 GRVLK L+ GL+H +GKT+V++GTR Sbjct: 204 AGRVLKKLQADGLLHARGKTVVLYGTR 230 >4CYD-A nrPDB Length = 225 Score = 174 bits (440), Expect = 4e-44, Method: Composition-based stats. Identities = 58/211 (27%), Positives = 97/211 (45%), Gaps = 5/211 (2%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 I ++ L+ R+ +TI G+ + L+ I G V + DGRE ++ Sbjct: 11 IFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARHAPDGRENLL 70 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 + D FGEL +F+ R++ E A ++ R I L Sbjct: 71 TIMGPSDMFGELSIFDP----GPRTSSAVCVTEVHAATMNSDMLRNWVADHPAIAEQLLR 126 Query: 124 QMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD-AMTHPDGMQIKITRQEIGRIVG 182 +A RLR+T + DL F DV GRVA+TLL L + + +T++EI ++VG Sbjct: 127 VLARRLRRTNASLADLIFTDVPGRVAKTLLQLANRFGTQEAGALRVNHDLTQEEIAQLVG 186 Query: 183 CSREMVGRVLKSLEEQGLVHVKGKTMVVFGT 213 SRE V + L + +G + ++GK++++ T Sbjct: 187 ASRETVNKALATFAHRGWIRLEGKSVLIVDT 217 >5E44-A nrPDB Length = 259 Score = 167 bits (423), Expect = 3e-42, Method: Composition-based stats. Identities = 46/211 (21%), Positives = 93/211 (44%), Gaps = 7/211 (3%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKST-IIYAGDRCETLFFIIKGSVTILIEDDDGRE 60 + I T LD+L R++ K + AGD + L+ I G++ + G E Sbjct: 37 LCIPFTLNDSELDQLDEIIERKKPIQKGQELFKAGDELKCLYAIRSGTIKSYTITEQGDE 96 Query: 61 MIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYT 120 I + +GD G + +E + ++ +A V EI Y +LS + ++ Sbjct: 97 QITAFHLAGDLVGFDAI-----TEAQHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQ 151 Query: 121 LGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMT-HPDGMQIKITRQEIGR 179 + M++ ++ + L+ + R+A L +L + P ++ +TR +IG Sbjct: 152 IMRLMSNEIKGDQEMILLLSKKNAEERLAAFLYNLSTRFHQRGFSPREFRLTMTRGDIGN 211 Query: 180 IVGCSREMVGRVLKSLEEQGLVHVKGKTMVV 210 +G + E + R+L ++ ++ VKGK + + Sbjct: 212 YLGLTVETISRLLGRFQKTEMLTVKGKYITI 242 >3I59-A nrPDB Length = 249 Score = 165 bits (418), Expect = 1e-41, Method: Composition-based stats. Identities = 57/211 (27%), Positives = 93/211 (44%), Gaps = 5/211 (2%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 I + + L + T+ G+ + L+ II G V I DGRE ++ Sbjct: 35 IFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGRRAPDGRENLL 94 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 + D FGEL +F+ R++ E + R EI L Sbjct: 95 TIMGPSDMFGELSIFDP----GPRTSSATTITEVRAVSMDRDALRSWIADRPEISEQLLR 150 Query: 124 QMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD-AMTHPDGMQIKITRQEIGRIVG 182 +A RLR+T + DL F DV GRVA+ LL L Q+ + +T++EI ++VG Sbjct: 151 VLARRLRRTNNNLADLIFTDVPGRVAKQLLQLAQRFGTQEGGALRVTHDLTQEEIAQLVG 210 Query: 183 CSREMVGRVLKSLEEQGLVHVKGKTMVVFGT 213 SRE V + L +G + ++GK++++ + Sbjct: 211 ASRETVNKALADFAHRGWIRLEGKSVLISDS 241 >3LA7-A nrPDB Length = 243 Score = 165 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 50/220 (22%), Positives = 95/220 (43%), Gaps = 18/220 (8%) Query: 7 TPKLKHL----DKLLAHCHRRR-----------YTAKSTIIYAGDRCETLFFIIKGSVTI 51 P+ H+ DK LA+ R+ + TI + GD E ++F++KG+V + Sbjct: 15 VPRGSHMIVTQDKALANVFRQMATGAFPPVVETFERNKTIFFPGDPAERVYFLLKGAVKL 74 Query: 52 LIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELS 111 + G E+ + L FG L L S++ A A E+ + + Sbjct: 75 SRVYEAGEEITVALLRENSVFGVLSLLTGNKSDRFYHA--VAFTPVELLSAPIEQVEQAL 132 Query: 112 QQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAM-THPDGMQI 170 +++ E+ + ++ R+ +T + LA D+ R+ LL LC+ + + Sbjct: 133 KENPELSMLMLRGLSSRILQTEMMIETLAHRDMGSRLVSFLLILCRDFGVPCADGITIDL 192 Query: 171 KITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVV 210 K++ Q I +G +R V R+L L E+ ++ + K + V Sbjct: 193 KLSHQAIAEAIGSTRVTVTRLLGDLREKKMISIHKKKITV 232 >2XKO-A nrPDB Length = 222 Score = 159 bits (401), Expect = 1e-39, Method: Composition-based stats. Identities = 46/190 (24%), Positives = 87/190 (45%), Gaps = 5/190 (2%) Query: 25 YTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSE 84 + TI + GD E ++ ++KG+V + + G E+ + L FG L L + S+ Sbjct: 27 FERGKTIFFPGDPAERVYLLVKGAVKLSRVYESGEEITVALLRENSVFGVLSLLTGQRSD 86 Query: 85 QERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDV 144 + A A ++ + ++ + E+ + ++ R+ +T + LA D+ Sbjct: 87 RFYHA--VAFTPVQLFSVPIEFMQKALIERPELANVMLQGLSSRILQTEMMIETLAHRDM 144 Query: 145 TGRVARTLLDLCQQPDAMTHPDGMQ--IKITRQEIGRIVGCSREMVGRVLKSLEEQGLVH 202 R+ LL LC+ + PDG+ +K++ Q I +G +R V R+L L E L+ Sbjct: 145 GSRLVSFLLILCRDF-GIPSPDGITIDLKLSHQAIAEAIGSTRVTVTRLLGDLRESKLIA 203 Query: 203 VKGKTMVVFG 212 + K + VF Sbjct: 204 IHKKRITVFN 213 >3H3Z-A nrPDB Length = 235 Score = 157 bits (398), Expect = 2e-39, Method: Composition-based stats. Identities = 43/197 (21%), Positives = 73/197 (37%), Gaps = 7/197 (3%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + + +H+D LL+ R Y T+ ++ + + +I G V + G E ++ Sbjct: 16 LIRSLPEQHVDALLSQAVWRSYDRGETLFLQEEKAQAIHVVIDGWVKLFRMTPTGSEAVV 75 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 G+ FGE A CEV I F L ++D EI ++ + Sbjct: 76 SVFTRGESFGEAVALR----NTPYPVSAEAVTPCEVMHIPSPVFVSLMRRDPEICISILA 131 Query: 124 QMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGC 183 L ++ L RVA LL+LC D T + + + I +G Sbjct: 132 TTFGHLHSLVAQLEQLKAQTGAQRVAEFLLELC---DCDTGACEVTLPYDKMLIAGRLGM 188 Query: 184 SREMVGRVLKSLEEQGL 200 E + R L+ G+ Sbjct: 189 KPESLSRAFSRLKAAGV 205 >3DKW-A nrPDB Length = 227 Score = 152 bits (383), Expect = 1e-37, Method: Composition-based stats. Identities = 41/209 (19%), Positives = 87/209 (41%), Gaps = 5/209 (2%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + L +LLA + + G+ +++I G V I +G+E I+ Sbjct: 16 LFEPLSPVQLQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIYRLTPEGQEKIL 75 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 N + F E +F + A +A V ++ S + Q ++ + L + Sbjct: 76 EVTNERNTFAEAMMFMDTPN---YVATAQAVVPSQLFRFSNKAYLRQLQDNTPLALALLA 132 Query: 124 QMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGC 183 +++ RL + ++ L+ + T RV R LL L A ++I + +Q + + Sbjct: 133 KLSTRLHQRIDEIETLSLKNATHRVVRYLLTLAA--HAPGENCRVEIPVAKQLVAGHLSI 190 Query: 184 SREMVGRVLKSLEEQGLVHVKGKTMVVFG 212 E R++ L ++G++H+ G+ + + Sbjct: 191 QPETFSRIMHRLGDEGIIHLDGREISILD 219 >4EV0-A nrPDB Length = 216 Score = 149 bits (375), Expect = 1e-36, Method: Composition-based stats. Identities = 60/207 (28%), Positives = 98/207 (47%), Gaps = 10/207 (4%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + H + +D L++ RR Y I Y GD + L+ + G V + G+E + Sbjct: 6 LFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQERTL 65 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 L G+ FGE+ L + E ERSA A + E+ + + L ++ + + L + Sbjct: 66 ALLGPGELFGEMSLLD----EGERSASAVAVEDTELLALFREDYLALIRRLPLVAHNLAA 121 Query: 124 QMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGC 183 +A RLR+ ++ L+F + RVA LL L +Q G +I E+ + G Sbjct: 122 LLARRLREADLELDLLSFEEARNRVAYALLKLLRQGL------GPLFQIRHHELAALAGT 175 Query: 184 SREMVGRVLKSLEEQGLVHVKGKTMVV 210 SRE V RVL +L E+G+V + T+ V Sbjct: 176 SRETVSRVLHALAEEGVVRLGPGTVEV 202 >3E6B-A nrPDB Length = 250 Score = 147 bits (372), Expect = 3e-36, Method: Composition-based stats. Identities = 39/203 (19%), Positives = 85/203 (41%), Gaps = 8/203 (3%) Query: 11 KHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGD 70 + L R + S +I G+ ++ F+++G + + I +DG E ++ Y Sbjct: 23 EKLRNYTQMGLIRDFAKGSAVIMPGEEITSMIFLVEGKIKLDIIFEDGSEKLLYYAGGNS 82 Query: 71 FFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLR 130 G+L G+ + A S R + + D ++++ + ++ Sbjct: 83 LIGKL---YPTGNNI----YATAMEPTRTCWFSEKSLRTVFRTDEDMIFEIFKNYLTKVA 135 Query: 131 KTTRKVGDLAFLDVTGRVARTLLDLCQ-QPDAMTHPDGMQIKITRQEIGRIVGCSREMVG 189 R+V ++ + T R+ R +LC Q + + + ++++ IG I G V Sbjct: 136 YYARQVAEMNTYNPTIRILRLFYELCSSQGKRVGDTYEITMPLSQKSIGEITGVHHVTVS 195 Query: 190 RVLKSLEEQGLVHVKGKTMVVFG 212 RVL SL+ + ++ K ++V+ Sbjct: 196 RVLASLKRENILDKKKNKIIVYN 218 >2GAU-A nrPDB Length = 232 Score = 144 bits (363), Expect = 2e-35, Method: Composition-based stats. Identities = 43/196 (21%), Positives = 74/196 (37%), Gaps = 4/196 (2%) Query: 17 LAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELG 76 ST+ GD LF++ +G + IL E GR I + G FFG Sbjct: 30 DKEIQPFPCKKASTVFSEGDIPNNLFYLYEGKIKILREGVYGRFHISRIVKPGQFFGMRP 89 Query: 77 LFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKV 136 F +E+ S+ A +V I L + ++ +A L R+ Sbjct: 90 YF----AEETCSSTAIAVENSKVLAIPVEAIEALLKGNTSFCRYFLKALAKELGYAERRT 145 Query: 137 GDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLE 196 L V GR+A TLL L + + I ++R+E+ + + R L + Sbjct: 146 VTLTQKHVRGRLAETLLILKENFGFENDGATLSIYLSREELATLSNMTVSNAIRTLSTFV 205 Query: 197 EQGLVHVKGKTMVVFG 212 + ++ + GK + + Sbjct: 206 SERMLALDGKRIKIID 221 >1ZYB-A nrPDB Length = 232 Score = 139 bits (350), Expect = 1e-33, Method: Composition-based stats. Identities = 40/192 (20%), Positives = 83/192 (43%), Gaps = 10/192 (5%) Query: 20 CHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFE 79 H ++ A TII +G+ C L F++KG ++I+ + +I + + LF Sbjct: 43 LHFIKHKAGETIIKSGNPCTQLCFLLKGEISIVTNAKENIYTVIEQIEAPYLIEPQSLF- 101 Query: 80 KEGSEQERSAWVRAKVECEVAEISYA-KFRELSQQDSEILYTLGSQMADRLRKTTRKVGD 138 G ++ A E IS A +L + D L + +++R + ++ D Sbjct: 102 --GMNTNYASSYVAHTEVHTVCISKAFVLSDLFRYDIFRLNYMN-IVSNRAQNLYSRLWD 158 Query: 139 LAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQ 198 LD+ ++ R L C++P K+ ++ R + +R + + L L++ Sbjct: 159 EPTLDLKSKIIRFFLSHCEKPQG-----EKTFKVKMDDLARCLDDTRLNISKTLNELQDN 213 Query: 199 GLVHVKGKTMVV 210 GL+ + K +++ Sbjct: 214 GLIELHRKEILI 225 >2H6C-A nrPDB Length = 232 Score = 136 bits (342), Expect = 8e-33, Method: Composition-based stats. Identities = 40/195 (20%), Positives = 82/195 (42%), Gaps = 16/195 (8%) Query: 23 RRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGEL----GLF 78 R + S II G+ ++ F++ G + + I +DG E ++ Y S G L Sbjct: 35 REFAKGSAIIMPGEDTTSMIFLMDGKIKLDIIFEDGSEKLLYYAGSNSLIGRLYPTGNNI 94 Query: 79 EKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGD 138 EQ R+ W S R + + D ++++ + ++ R+V + Sbjct: 95 YATAMEQTRTCWF-----------SEECLRVIFRTDEDMIFEIFKNYLTKVAYYARQVAE 143 Query: 139 LAFLDVTGRVARTLLDLCQ-QPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEE 197 + + T R+ R +LC Q + + + ++++ IG I G V +VL L++ Sbjct: 144 INTYNPTIRILRLFYELCSSQGKRVGDTYEITMPLSQKSIGEITGAHHVTVSKVLACLKK 203 Query: 198 QGLVHVKGKTMVVFG 212 + ++ K +V+ Sbjct: 204 ENILDKKKNKFIVYN 218 >3E97-A nrPDB Length = 231 Score = 135 bits (341), Expect = 1e-32, Method: Composition-based stats. Identities = 42/197 (21%), Positives = 77/197 (39%), Gaps = 5/197 (2%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 + + L R + ++ E L + G V + GRE ++G + + Sbjct: 22 MREALKVVTERNFQPDELVVEQDAEGEALHLVTTGVVRVSRVSLGGRERVLGDIYAPGVV 81 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKT 132 GE + + QERSA VRA + F + ++ +L+ L +A R+ Sbjct: 82 GETAVL----AHQERSASVRALTPVRTLMLHREHFELILRRHPRVLWNLAEMLARRVTFL 137 Query: 133 TRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVL 192 ++ + + +L +Q A P + + Q+I SRE V RVL Sbjct: 138 NDELIAFG-QNTEAALTHVFANLYRQRLAAGVPQPEVLPLGTQDIMARTSSSRETVSRVL 196 Query: 193 KSLEEQGLVHVKGKTMV 209 K LE ++ V +++ Sbjct: 197 KRLEAHNILEVSPRSVT 213 >1FT9-A nrPDB Length = 222 Score = 134 bits (336), Expect = 4e-32, Method: Composition-based stats. Identities = 43/188 (22%), Positives = 78/188 (41%), Gaps = 14/188 (7%) Query: 21 HRRRYTAKSTIIYAGDRCET-LFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFE 79 R + AK +++ G+ E +F ++ G + + + ++ RE+ + YL SGD F Sbjct: 23 FRSKIHAKGSLVCTGEGDENGVFVVVDGRLRVYLVGEE-REISLFYLTSGDMFCM----- 76 Query: 80 KEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDL 139 V A EV F + Q + + L + + L R + DL Sbjct: 77 ------HSGCLVEATERTEVRFADIRTFEQKLQTCPSMAWGLIAILGRALTSCMRTIEDL 130 Query: 140 AFLDVTGRVARTLLDLCQQPDAMTHPDGM-QIKITRQEIGRIVGCSREMVGRVLKSLEEQ 198 F D+ R+A +D T + + T +EI ++G SR+ L SL ++ Sbjct: 131 MFHDIKQRIAGFFIDHANTTGRQTQGGVIVSVDFTVEEIANLIGSSRQTTSTALNSLIKE 190 Query: 199 GLVHVKGK 206 G + +G+ Sbjct: 191 GYISRQGR 198 >4I2O-A nrPDB Length = 243 Score = 133 bits (335), Expect = 5e-32, Method: Composition-based stats. Identities = 42/193 (21%), Positives = 74/193 (38%), Gaps = 10/193 (5%) Query: 22 RRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKE 81 Y I + E ++ ++ G+V DGR I + GD FG Sbjct: 42 EFSYRKDEEIYGEDEPAEYVYQVVTGAVRSYKLLSDGRRQIGAFHLPGDVFG-------L 94 Query: 82 GSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAF 141 S A ++ V + + + + D ++ L + A LR + L Sbjct: 95 ESGPSHRLAAEAIIDTSVRLVKRSSLEKAAGIDVQVARKLWAMTAGELRHAEDHMLLLGR 154 Query: 142 LDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLV 201 RVA LL++ ++ + M + ++R++IG +G + E V R L L QG++ Sbjct: 155 KTAMERVATFLLEMDRR---LAVAGMMALPMSRRDIGDYLGLTLETVSRALSQLHTQGIL 211 Query: 202 HVKGKTMVVFGTR 214 G +V R Sbjct: 212 GFSGARQIVLRNR 224 >2ZCW-A nrPDB Length = 202 Score = 129 bits (324), Expect = 1e-30, Method: Composition-based stats. Identities = 45/196 (22%), Positives = 82/196 (41%), Gaps = 14/196 (7%) Query: 21 HRRRYTAKSTIIYAGDRC--ETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLF 78 + A I+Y G + + +++G V + D++G + + + G FFGE LF Sbjct: 6 ETVSFKAGDVILYPGVPGPRDRAYRVLEGLVRLEAVDEEGNALTLRLVRPGGFFGEEALF 65 Query: 79 EKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGD 138 QER + A + + + D E+L L ++ L + R++ Sbjct: 66 -----GQERIYFAEAATDVRLEPLPE-------NPDPELLKDLAQHLSQGLAEAYRRIER 113 Query: 139 LAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQ 198 LA + R+A LL+L + P A + +K T E+ VG RE V +V+ L + Sbjct: 114 LATQRLKNRMAAALLELSETPLAHEEEGKVVLKATHDELAAAVGSVRETVTKVIGELARE 173 Query: 199 GLVHVKGKTMVVFGTR 214 G + + + + Sbjct: 174 GYIRSGYGKIQLLDLK 189 >3B02-A nrPDB Length = 195 Score = 125 bits (315), Expect = 9e-30, Method: Composition-based stats. Identities = 45/190 (23%), Positives = 81/190 (42%), Gaps = 11/190 (5%) Query: 23 RRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEG 82 +R+ K TI G+ TL+ + +G V ++ DGR + + ++ GD+FGE L Sbjct: 2 KRFARKETIYLRGEEARTLYRLEEGLVRVVELLPDGRLITLRHVLPGDYFGEEAL----- 56 Query: 83 SEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFL 142 + A E V + D E L+ + +A ++R+ L Sbjct: 57 EGKAYRYTAEAMTEAVVQGLEPRA------MDHEALHRVARNLARQMRRVQAYEAHLQTG 110 Query: 143 DVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVH 202 ++ R+AR LL L P + G+ + ++ +EI RE V +VL L +GL+ Sbjct: 111 ELRARIARYLLFLADTPLSARDRQGIYVTVSHEEIADATASIRESVSKVLADLRREGLIA 170 Query: 203 VKGKTMVVFG 212 + + + Sbjct: 171 TAYRRVYLLD 180 >2FMY-A nrPDB Length = 220 Score = 118 bits (296), Expect = 2e-27, Method: Composition-based stats. Identities = 33/202 (16%), Positives = 79/202 (39%), Gaps = 15/202 (7%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + + +L +RY+ K+ + +F + G V + + +D +E + Sbjct: 11 LLEVLNSEEYSGVLKEFREQRYSKKAILYTPNTERNLVFLVKSGRVRVYLAYED-KEFTL 69 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 L +GD F A+++A + + F+ + + + Sbjct: 70 AILEAGDIFC-----------THTRAFIQAMEDTTILYTDIRNFQNIVVEFPAFSLNMVK 118 Query: 124 QMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIK--ITRQEIGRIV 181 + D L+ + + L F D R+A L+ + P G++++ + +EI ++ Sbjct: 119 VLGDLLKNSLTIINGLVFKDARLRLAEFLVQ-AAMDTGLKVPQGIKLELGLNTEEIALML 177 Query: 182 GCSREMVGRVLKSLEEQGLVHV 203 G +R+ V +L ++ G++ Sbjct: 178 GTTRQTVSVLLNDFKKMGILER 199 >1O5L-A nrPDB Length = 213 Score = 91.3 bits (225), Expect = 3e-19, Method: Composition-based stats. Identities = 38/202 (18%), Positives = 80/202 (39%), Gaps = 9/202 (4%) Query: 12 HLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDF 71 L KLL + + + D E + +++G++ ++G+ + I + Sbjct: 14 DLKKLLPCGKVIVFRKGEIVKHQDDPIEDVLILLEGTLKTEHVSENGKTLEIDEIKPVQI 73 Query: 72 FGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRK 131 +F SE V A ++ I F +L +D E+L +++ R Sbjct: 74 IASGFIFS---SEPRFPVNVVAGENSKILSIPKEVFLDLLMKDRELLLFFLKDVSEHFRV 130 Query: 132 TTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRV 191 + K+ L + ++ L+ M + + +T +E+ R+ GC+R + RV Sbjct: 131 VSEKLFFLTTKTLREKLMNFLVRH------MNEKRELTLPVTLEELSRLFGCARPALSRV 184 Query: 192 LKSLEEQGLVHVKGKTMVVFGT 213 + LE +G + G+ + V Sbjct: 185 FQELEREGYIEKHGRRIKVLKN 206 >3DV8-A nrPDB Length = 220 Score = 89.4 bits (220), Expect = 1e-18, Method: Composition-based stats. Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 9/201 (4%) Query: 15 KLLAHCHRRRYTAKSTIIYAGDR-CETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFG 73 KL++ ++ K TII+ G+ C L + G + I D+GRE+ + L D Sbjct: 20 KLISDNLITQHVKKGTIIHNGNMDCTGLLLVKSGQLRTYILSDEGREITLYRLFDMDM-C 78 Query: 74 ELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTT 133 L S Q + A+ + ++ I ++ + + + + MA R Sbjct: 79 LLSASCIMRSIQF-EVTIEAEKDTDLWIIPAEIYKGIMKDSAPVANYTNELMATRFSDVM 137 Query: 134 RKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLK 193 + + + + RVA LL+ + ++KIT + I +G RE++ R+L+ Sbjct: 138 WLIEQIMWKSLDKRVASFLLE------ETSIEGTNELKITHETIANHLGSHREVITRMLR 191 Query: 194 SLEEQGLVHVKGKTMVVFGTR 214 + +GLV + + + ++ Sbjct: 192 YFQVEGLVKLSRGKITILDSK 212 >6CJQ-A nrPDB Length = 456 Score = 88.2 bits (217), Expect = 2e-18, Method: Composition-based stats. Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 7/127 (5%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM 61 V + + + ++ H Y II AG+ ++FI +GSV +L D+ R Sbjct: 318 VPLFKGAGEEFIRDIILHLEPVIYGPGEYIIRAGEMGSDVYFINRGSVEVLSADEKTRY- 376 Query: 62 IIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTL 121 L+ G FFGE+ L + R+A VRA+ C++ + F + + EI + Sbjct: 377 --AILSEGQFFGEMALILR----APRTATVRARAFCDLYRLDKETFDRILSRYPEIAAQI 430 Query: 122 GSQMADR 128 R Sbjct: 431 QELAVRR 437 >5KBF-A nrPDB Length = 301 Score = 83.2 bits (204), Expect = 7e-17, Method: Composition-based stats. Identities = 33/134 (24%), Positives = 59/134 (44%), Gaps = 14/134 (10%) Query: 4 ITHTPKLKHLDKL----LAHCHRRR-YTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDG 58 ++H LK +D +A C + + Y II G+ +T F +I G+ + D Sbjct: 167 LSHVNILKDMDPYERCKVADCLKSKSYNDGEIIIKEGEEGDTFFILIDGN---AVASKDN 223 Query: 59 REMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEIL 118 + +I GD+FGEL L + + R+A ++A+ C+V + F+ L +IL Sbjct: 224 K--VIKTYTKGDYFGELALLK----NKPRAATIKAQNFCQVVYLDRKSFKRLLGPIEDIL 277 Query: 119 YTLGSQMADRLRKT 132 + L + Sbjct: 278 HRNVENYKKVLNEL 291 Score = 72.4 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 48/132 (36%), Gaps = 4/132 (3%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + + K + ++ + II GD + L+ I +G V I ++ ++ ++ Sbjct: 49 LFNHLNKKEFEIIVNAFFDKNVEKGVNIINEGDYGDLLYVIDQGEVEIYKTKENNKKEVL 108 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 L S D FGEL L +R+A A +C + + F + + + Sbjct: 109 TVLKSKDVFGELALLY----NSKRAATATALTKCHLWALDRESFTYIIKDMVAKKRKMYE 164 Query: 124 QMADRLRKTTRK 135 + + Sbjct: 165 DILSHVNILKDM 176 >5K7L-A nrPDB Length = 857 Score = 80.5 bits (197), Expect = 5e-16, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 62/142 (43%), Gaps = 12/142 (8%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 L L I +AG+ ++L F++ GS+ ++ +D+ ++ L GD F Sbjct: 563 LRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDE-----VVAILGKGDVF 617 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQM----ADR 128 G+ +F KE + + A VRA C++ I +++ + + ++ + R Sbjct: 618 GD--VFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLR 675 Query: 129 LRKTTRKVGDLAFLDVTGRVAR 150 R RK+ D+ + R+ R Sbjct: 676 KRIVFRKISDVKREE-EERMKR 696 >5W5B-A nrPDB Length = 236 Score = 79.4 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 31/201 (15%), Positives = 72/201 (35%), Gaps = 14/201 (6%) Query: 12 HLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDF 71 + L + + + + +A + ++ + G + + R ++ L+ GD Sbjct: 41 DVSALAETLQVKEFAPGAVVFHADQTADGVWIVRHGLIEL-AVGSRRRRAVVNILHPGDV 99 Query: 72 FGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRK 131 G++ L E RA + + F L I S +A R+ Sbjct: 100 DGDIPLLL----EMPMVYTGRALTQATCLFLDRQAFERLLATHPAIARRWLSSVAQRVST 155 Query: 132 TTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRV 191 ++ + + +VA+ LLD +I++ ++ + ++G R + ++ Sbjct: 156 AQIRLMGMLGRPLPAQVAQLLLDEAIDA---------RIELAQRTLAAMLGAQRPSINKI 206 Query: 192 LKSLEEQGLVHVKGKTMVVFG 212 LK E L+ V + + Sbjct: 207 LKEFERDRLITVGYAVIEITD 227 >5V4S-A nrPDB Length = 465 Score = 79.0 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 7/114 (6%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 + L+ + TI G++ + L+ + +GSV IL D+ I+ L G FF Sbjct: 354 VTSLVFSMKPMIFLEGDTIFRRGEKGDDLYILSEGSVDILDSDEK---TILLSLQEGQFF 410 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMA 126 GEL L + RSA VRA CE+ +S F + ++ S+ + +A Sbjct: 411 GELALV----MDAPRSATVRATTTCEIYTLSKTDFDNVLKRFSQFRSAIEESVA 460 >4CHV-A nrPDB Length = 361 Score = 77.4 bits (189), Expect = 4e-15, Method: Composition-based stats. Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 11/127 (8%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM 61 V + L +++ R A + I G+ + +FF+++GSV++ + Sbjct: 233 VPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVVEGSVSVATPNPVE--- 289 Query: 62 IIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTL 121 L G FFGE+ L E RSA V A + + A F+ L EI Sbjct: 290 ----LGPGAFFGEMALISGE----PRSATVSAATTVSLLSLHSADFQMLCSSSPEIAEIF 341 Query: 122 GSQMADR 128 +R Sbjct: 342 RKTALER 348 >4F8A-A nrPDB Length = 160 Score = 76.3 bits (186), Expect = 9e-15, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 51/113 (45%), Gaps = 7/113 (6%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 L L I +AG+ ++L F++ GS+ ++ +D+ ++ L GD F Sbjct: 43 LRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDE-----VVAILGKGDVF 97 Query: 73 GELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQM 125 G+ +F KE + + A VRA C++ I +++ + + ++ + Sbjct: 98 GD--VFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNL 148 >5VA1-A nrPDB Length = 795 Score = 74.0 bits (180), Expect = 5e-14, Method: Composition-based stats. Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 28/134 (20%) Query: 12 HLDK-LLAHCHRRR------------------YTAKSTIIYAGDRCETLFFIIKGSVTIL 52 HL++ LL HC R T+++AGD L+FI +GS+ IL Sbjct: 491 HLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEIL 550 Query: 53 IEDDDGREMIIGYLNSGDFFGE-LGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELS 111 D +++ L D FGE L L+ + G + + VRA C++ +I E+ Sbjct: 551 RGD-----VVVAILGKNDIFGEPLNLYARPG---KSNGDVRALTYCDLHKIHRDDLLEVL 602 Query: 112 QQDSEILYTLGSQM 125 E S + Sbjct: 603 DMYPEFSDHFWSSL 616 >2N7G-A nrPDB Length = 154 Score = 72.4 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 33/134 (24%), Positives = 53/134 (39%), Gaps = 27/134 (20%) Query: 11 KHLDKLLAHCHRRR------------------YTAKSTIIYAGDRCETLFFIIKGSVTIL 52 + + LL HC R T+++AGD L+FI +GS+ IL Sbjct: 21 QSMRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEIL 80 Query: 53 IEDDDGREMIIGYLNSGDFFGE-LGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELS 111 D +++ L D FGE L L+ + G + + VRA C++ +I E+ Sbjct: 81 RGD-----VVVAILGKNDIFGEPLNLYARPG---KSNGDVRALTYCDLHKIHRDDLLEVL 132 Query: 112 QQDSEILYTLGSQM 125 E S + Sbjct: 133 DMYPEFSDHFWSSL 146 >4DIN-B nrPDB Length = 381 Score = 67.4 bits (163), Expect = 4e-12, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 44/102 (43%), Gaps = 5/102 (4%) Query: 20 CHRRRYTAKSTIIYAGDRCETLFFIIKGSVTIL-IEDDDGREMIIGYLNSGDFFGELGLF 78 ++ I+ G+ + + I +G+ ++L + + +G L D+FGE+ L Sbjct: 271 LEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALL 330 Query: 79 EKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYT 120 + R+A V A+ + ++ +F + SEIL Sbjct: 331 L----NRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKR 368 Score = 61.6 bits (148), Expect = 3e-10, Method: Composition-based stats. Identities = 19/131 (14%), Positives = 46/131 (35%), Gaps = 9/131 (6%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + + + A T+I G+ + + + +G V + + + + Sbjct: 137 LFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNGE-----WV 191 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 ++ G FGEL L R+A V+AK + ++ I +R + + + Sbjct: 192 TNISEGGSFGELALIYGT----PRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYE 247 Query: 124 QMADRLRKTTR 134 + ++ Sbjct: 248 EFLSKVSILES 258 >5J3U-A nrPDB Length = 261 Score = 67.0 bits (162), Expect = 5e-12, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 48/110 (43%), Gaps = 5/110 (4%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + ++ K L+ ++ ++ A + +I GD E L+ + G + DG E ++ Sbjct: 21 LFNSLDEKDLNTVILAMQEKKIEASTCLIREGDDGECLYIVQSGELNCSKLI-DGEERVV 79 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQ 113 + GD FGEL L R+A V + C++ E+ F + + Sbjct: 80 KVVGPGDAFGELALLY----NAPRAATVTSVSACDLWELGRDTFNAIVKD 125 Score = 58.2 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 5/100 (5%) Query: 20 CHRRRYTAKSTIIYAGDRCETLFFIIKGS-VTILIEDDDGREMIIGYLNSGDFFGELGLF 78 +T + I+ G+ + + + +GS V + + +GD+FGEL L Sbjct: 159 LRTEMFTDGAYIVRQGELGDVFYIVEEGSAVATKSFGPGQPPIEVKKYQAGDYFGELALI 218 Query: 79 EKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEIL 118 +E+ R+A V A C+VA + F+ L ++L Sbjct: 219 ----NEEPRAANVIAHGICKVACLERKSFKRLMGSVQDLL 254 >6BYS-B nrPDB Length = 379 Score = 66.3 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 24/107 (22%), Positives = 46/107 (42%), Gaps = 5/107 (4%) Query: 20 CHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDFFGELGLF 78 ++ I+ G+ + F I++GS +L + E + +G L D+FGE+ L Sbjct: 269 LEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALL 328 Query: 79 EKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQM 125 + R+A V A+ + ++ +F + S+IL Q Sbjct: 329 ----MNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 371 Score = 60.9 bits (146), Expect = 4e-10, Method: Composition-based stats. Identities = 23/143 (16%), Positives = 49/143 (34%), Gaps = 11/143 (7%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + + + A T+I GD + + I +G + + + ++ Sbjct: 135 LFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWA----- 189 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 + G FGEL L R+A V+AK ++ I +R + + + Sbjct: 190 TSVGEGGSFGELALIYGT----PRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYE 245 Query: 124 QMADR--LRKTTRKVGDLAFLDV 144 + + + ++ K L D Sbjct: 246 EFLSKVSILESLDKWERLTVADA 268 >2QCS-B nrPDB Length = 291 Score = 64.7 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 46/107 (42%), Gaps = 5/107 (4%) Query: 20 CHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDFFGELGLF 78 ++ I+ G+ + F I++GS +L + E + +G L D+FGE+ L Sbjct: 180 LEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALL 239 Query: 79 EKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQM 125 + ++A V A+ + ++ +F + S+IL Q Sbjct: 240 ----MNRPKAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 282 Score = 61.2 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 23/143 (16%), Positives = 49/143 (34%), Gaps = 11/143 (7%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + + + A T+I GD + + I +G + + + ++ Sbjct: 46 LFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWA----- 100 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 + G FGEL L R+A V+AK ++ I +R + + + Sbjct: 101 TSVGEGGSFGELALIYGT----PRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYE 156 Query: 124 QMADR--LRKTTRKVGDLAFLDV 144 + + + ++ K L D Sbjct: 157 EFLSKVSILESLDKWERLTVADA 179 >3J4Q-B nrPDB Length = 402 Score = 64.3 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 59/146 (40%), Gaps = 11/146 (7%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDD----- 56 V + + ++ K++ + Y II G++ ++ + I G V+ILI Sbjct: 257 VPLFKSLEMSERMKIVDVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKSNK 316 Query: 57 --DGREMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQD 114 +E+ I + + G +FGEL L + + R+A A + + + F L Sbjct: 317 NGGNQEVEIAHCHKGQYFGELALV----TNKPRAASAYAVGDVKCLVMDVQAFERLLGPC 372 Query: 115 SEILYTLGSQMADRLRKTTRKVGDLA 140 +I+ S ++L K DL Sbjct: 373 MDIMKRNISHYEEQLVKMFGSNLDLM 398 Score = 53.2 bits (126), Expect = 9e-08, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 46/122 (37%), Gaps = 5/122 (4%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM 61 + + + L ++L + +I GD + + I +G+ IL D + Sbjct: 135 ILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDIL-VTKDNQTR 193 Query: 62 IIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTL 121 +G ++ FGEL L R+A + A E + + FR + +++ + Sbjct: 194 SVGQYDNRGSFGELALMY----NTPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKM 249 Query: 122 GS 123 Sbjct: 250 FE 251 >2QVS-B nrPDB Length = 310 Score = 62.4 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 58/146 (39%), Gaps = 11/146 (7%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDD----- 56 V + + ++ K++ + Y II G++ ++ + I G V+ILI Sbjct: 165 VPLFKSLEMSERMKIVDVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKSNK 224 Query: 57 --DGREMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQD 114 +E+ I + + G +FGEL L + + R+A + + + F L Sbjct: 225 NGGNQEVEIAHCHKGQYFGELALV----TNKPRAASAYGVGDVKCLVMDVQAFERLLGPC 280 Query: 115 SEILYTLGSQMADRLRKTTRKVGDLA 140 +I+ S ++L K DL Sbjct: 281 MDIMKRNISHYEEQLVKMFGSNLDLM 306 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 46/122 (37%), Gaps = 5/122 (4%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM 61 + + + L ++L + +I GD + + I +G+ IL D + Sbjct: 43 ILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDIL-VTKDNQTR 101 Query: 62 IIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTL 121 +G ++ FGEL L R+A + A E + + FR + +++ + Sbjct: 102 SVGQYDNRGSFGELALMY----NTPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKM 157 Query: 122 GS 123 Sbjct: 158 FE 159 >5JON-A nrPDB Length = 517 Score = 62.4 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 28/126 (22%), Positives = 50/126 (39%), Gaps = 9/126 (7%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + + +L + II G + ++FI G V++L +EM + Sbjct: 394 LFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLT--KGNKEMKL 451 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 G +FGE+ L + R+A VRA C + +S F E+ ++ + + Sbjct: 452 SD---GSYFGEICLLTR----GRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFET 504 Query: 124 QMADRL 129 DRL Sbjct: 505 VAIDRL 510 >5DYK-A nrPDB Length = 853 Score = 62.4 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 27/119 (22%), Positives = 47/119 (39%), Gaps = 9/119 (7%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM 61 V++ + + C + + + TI+ GD + L+ + +G T+ I D++ Sbjct: 174 VSVFDMLTEAQKNMITNACVIQNFKSGETIVKQGDYGDVLYILKEGKATVYINDEE---- 229 Query: 62 IIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYT 120 I L G +FGE L E RSA + AK A I + +L+ Sbjct: 230 -IRVLEKGSYFGERALLYDE----PRSATIIAKEPTACASICRKLLNIVLGNLQVVLFR 283 Score = 60.1 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 33/147 (22%), Positives = 55/147 (37%), Gaps = 18/147 (12%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 I K + L+ RY II G+ + I G V I+ + + Sbjct: 418 IFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIVK-----NKKRL 472 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKV-ECEVAEISYAKFRELSQQDSEILYTLG 122 L D+FGE L E R+A V +KV E + + F ++ Q + Sbjct: 473 RTLGKNDYFGERALLYDE----PRTASVISKVNNVECWFVDKSVFLQIIQG------PML 522 Query: 123 SQMADRLRKTTRKVG--DLAFLDVTGR 147 + + +R++ KV +L + GR Sbjct: 523 AHLEERIKMQDTKVEMDELETERIIGR 549 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 40/107 (37%), Gaps = 9/107 (8%) Query: 7 TPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYL 66 T + L + + + + +I G++ F I G + + D + + Sbjct: 61 TLNDNEILTLSNYMQFFVFKSGNLVIKQGEKGSYFFIINSGKFDVYVNDKK-----VKTM 115 Query: 67 NSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQ 113 G FGE L +RSA + A+ + + + + FR +Q Sbjct: 116 GKGSSFGEAALIH----NTQRSATIIAETDGTLWGVQRSTFRATLKQ 158 >3SHR-A nrPDB Length = 299 Score = 60.9 bits (146), Expect = 4e-10, Method: Composition-based stats. Identities = 31/109 (28%), Positives = 41/109 (37%), Gaps = 5/109 (4%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMI-IGYLNSGDF 71 L KL Y II G R +T F I KG V + ED + + + L GD+ Sbjct: 173 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGKVNVTREDSPNEDPVFLRTLGKGDW 232 Query: 72 FGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYT 120 FGE L E R+A V A I F+ L ++ Sbjct: 233 FGEKAL----QGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNK 277 Score = 55.5 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 41/106 (38%), Gaps = 9/106 (8%) Query: 8 PKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLN 67 +L + +++ + Y S II GD ++ + G V + E + + Sbjct: 50 LELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVK-----LCTMG 104 Query: 68 SGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQ 113 G FGEL + R+A V+ V ++ I F+ + + Sbjct: 105 PGKVFGELAILY----NCTRTATVKTLVNVKLWAIDRQCFQTIMMR 146 >5H3O-A nrPDB Length = 738 Score = 60.5 bits (145), Expect = 6e-10, Method: Composition-based stats. Identities = 27/187 (14%), Positives = 65/187 (34%), Gaps = 8/187 (4%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFF 72 L +L+ + ++ I GD ++ + +G + + DDDG+ + L G F Sbjct: 507 LAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV--VDDDGK-KVFVTLQEGSVF 563 Query: 73 GELGLF--EKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLR 130 GEL + + R+A VR+ ++ +S ++ + L + Sbjct: 564 GELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPD-ARKLLLAKGREIL 622 Query: 131 KTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGR 190 K + + A + + + + + ++ + + EM+ + Sbjct: 623 KKDNLLDENAPEE--QKTVEEIAEHLNNAVKVLQTRMARLIVEHSSTEGKLMKRIEMLEK 680 Query: 191 VLKSLEE 197 L + Sbjct: 681 HLSRYKA 687 >4Z07-A nrPDB Length = 262 Score = 60.5 bits (145), Expect = 6e-10, Method: Composition-based stats. Identities = 31/109 (28%), Positives = 41/109 (37%), Gaps = 5/109 (4%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIED-DDGREMIIGYLNSGDF 71 L KL Y II G R +T F I KG+V + ED + + L GD+ Sbjct: 156 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDW 215 Query: 72 FGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYT 120 FGE L E R+A V A I F+ L ++ Sbjct: 216 FGEKAL----QGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNK 260 Score = 56.2 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 41/106 (38%), Gaps = 9/106 (8%) Query: 8 PKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLN 67 +L + +++ + Y S II GD ++ + G V + E + + Sbjct: 33 LELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVK-----LCTMG 87 Query: 68 SGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQ 113 G FGEL + R+A V+ V ++ I F+ + + Sbjct: 88 PGKVFGELAILY----NCTRTATVKTLVNVKLWAIDRQCFQTIMMR 129 >5U6P-A nrPDB Length = 660 Score = 60.1 bits (144), Expect = 7e-10, Method: Composition-based stats. Identities = 28/183 (15%), Positives = 65/183 (35%), Gaps = 20/183 (10%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 + + +L+ + II G + ++FI G ++ + + Sbjct: 475 LFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEMK--- 531 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDS-------- 115 L G +FGE+ L ++ R+A VRA C + +S F E+ ++ Sbjct: 532 --LTDGSYFGEICLL----TKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFET 585 Query: 116 ---EILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKI 172 + L +G + + L+K + + F + + + ++ ++ P + Sbjct: 586 VAIDRLDRIGKKNSILLQKFQKDLNTGVFNNQENEILKQIVKHDREMVQAALPRESSSVL 645 Query: 173 TRQ 175 Sbjct: 646 NTD 648 >5FET-A nrPDB Length = 847 Score = 59.7 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 9/119 (7%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM 61 V++ + + C + + TI+ GD + LF + +G T+ I D + Sbjct: 168 VSVFDMLTEAQKNMITNACVIQMFKPGETIVKQGDYGDVLFILKEGKATVFINDKE---- 223 Query: 62 IIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYT 120 I LN G +FGE L E RSA + AK A I + +L+ Sbjct: 224 -IRVLNKGSYFGERALLYDE----PRSATIIAKEPTACASICRKLLNIVLGNLQVVLFR 277 Score = 57.4 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 52/147 (35%), Gaps = 18/147 (12%) Query: 4 ITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMII 63 I + + L+ RY II G+ + I G V + + Sbjct: 412 IFRYLSEQQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEVTKNGKR-----L 466 Query: 64 GYLNSGDFFGELGLFEKEGSEQERSAWVRAK-VECEVAEISYAKFRELSQQDSEILYTLG 122 L D+FGE L E R+A + +K E + + F ++ Q + Sbjct: 467 RTLGKNDYFGERALLYDE----PRTASIISKATSVECWFVDKSVFLQIIQG------PML 516 Query: 123 SQMADRLRKTTRKVG--DLAFLDVTGR 147 + + +R++ KV +L + GR Sbjct: 517 THLEERIKMQDTKVEMHELETERIIGR 543 Score = 54.7 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 38/107 (35%), Gaps = 9/107 (8%) Query: 7 TPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYL 66 T + L + + +I G++ F I G + + D + + Sbjct: 55 TLNDNEILTLSNYMQFFVFKGGDLVIKQGEKGSYFFIINSGKFDVYVNDKK-----VKSM 109 Query: 67 NSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQ 113 G FGE L +RSA + A+ + + + + FR +Q Sbjct: 110 GKGSSFGEAALIH----NTQRSATIMAETDGTLWGVQRSTFRATLKQ 152 >6BQ8-A nrPDB Length = 152 Score = 59.3 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 30/136 (22%), Positives = 52/136 (38%), Gaps = 6/136 (4%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDD-GRE 60 V++ L K++ Y II G+ T F + KG V + + + Sbjct: 18 VSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQP 77 Query: 61 MIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKV-ECEVAEISYAKFRELSQQDSEILY 119 +I L G++FGE L S+ RSA + A+ + I F + E+ Sbjct: 78 QLIKTLQKGEYFGEKALI----SDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQK 133 Query: 120 TLGSQMADRLRKTTRK 135 L +A+ R ++ Sbjct: 134 YLEGYVANLNRDDEKR 149 >3UKN-A nrPDB Length = 212 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 46/110 (41%), Gaps = 7/110 (6%) Query: 26 TAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQ 85 +I GD + ++F+ GS+ +L ++ L GD G L +++ + Sbjct: 104 APGEFLIRQGDALQAIYFVCSGSMEVLK-----DNTVLAILGKGDLIGSDSLTKEQVIKT 158 Query: 86 ERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRK 135 +A V+A C++ IS RE+ + E S++ L R+ Sbjct: 159 --NANVKALTYCDLQYISLKGLREVLRLYPEYAQKFVSEIQHDLTYNLRE 206 >4QX5-A nrPDB Length = 153 Score = 58.9 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 31/109 (28%), Positives = 41/109 (37%), Gaps = 5/109 (4%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIED-DDGREMIIGYLNSGDF 71 L KL Y II G R +T F I KG+V + ED + + L GD+ Sbjct: 29 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDW 88 Query: 72 FGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYT 120 FGE L E R+A V A I F+ L ++ Sbjct: 89 FGEKAL----QGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNK 133 >4L11-A nrPDB Length = 204 Score = 58.9 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 40/92 (43%), Gaps = 7/92 (7%) Query: 26 TAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQ 85 +++ GD L+FI +GS+ IL +D +++ L D FGE + Sbjct: 101 PPGDILVHKGDVLTYLYFIARGSIEILKDD-----VVMAILGKDDIFGENPCIH--STLG 153 Query: 86 ERSAWVRAKVECEVAEISYAKFRELSQQDSEI 117 + ++ V+A C++ +I ++ E Sbjct: 154 KSNSNVKALTYCDLHKIHRDDLLDVLDLFPEF 185 >5JAX-A nrPDB Length = 135 Score = 58.6 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 31/109 (28%), Positives = 41/109 (37%), Gaps = 5/109 (4%) Query: 13 LDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIED-DDGREMIIGYLNSGDF 71 L KL Y II G R +T F I KG+V + ED + + L GD+ Sbjct: 29 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDW 88 Query: 72 FGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYT 120 FGE L E R+A V A I F+ L ++ Sbjct: 89 FGEKAL----QGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNK 133 >1CX4-A nrPDB Length = 305 Score = 58.2 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 42/111 (37%), Gaps = 10/111 (9%) Query: 25 YTAKSTIIYAGDRCETLFFIIKGSVTILIE------DDDGREMIIGYLNSGDFFGELGLF 78 Y II GD ++ F + G V I ++ ++ + I G +FGEL L Sbjct: 184 YNDGEQIIAQGDSADSFFIVESGEVRITMKRKGKSDIEENGAVEIARCLRGQYFGELALV 243 Query: 79 EKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRL 129 + + R+A A + + F L EI+ + ++L Sbjct: 244 ----TNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQL 290 Score = 53.9 bits (128), Expect = 5e-08, Method: Composition-based stats. Identities = 27/150 (18%), Positives = 54/150 (36%), Gaps = 18/150 (12%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM 61 + + + + ++L + +I GD + + I +G+ I ++ D Sbjct: 39 ILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRC 98 Query: 62 IIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTL 121 + Y N G FGEL L R+A + A + + FR + + Sbjct: 99 VGNYDNRGS-FGELALMY----NTPRAATITATSPGALWGLDRVTFRRI----------I 143 Query: 122 GSQMADRLRKTTRKVGDLAF---LDVTGRV 148 A + + + L F L+V+ R+ Sbjct: 144 VKNNAKKRKMYESFIESLPFLKSLEVSERL 173 >4X6Q-B nrPDB Length = 416 Score = 57.4 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 25/111 (22%), Positives = 41/111 (36%), Gaps = 10/111 (9%) Query: 25 YTAKSTIIYAGDRCETLFFIIKGSVTIL------IEDDDGREMIIGYLNSGDFFGELGLF 78 Y II GD ++ F + G V I E ++ + I G +FGEL L Sbjct: 295 YNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALV 354 Query: 79 EKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRL 129 + + R+A A + + F L EI+ + ++L Sbjct: 355 ----TNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQL 401 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 26/150 (17%), Positives = 54/150 (36%), Gaps = 18/150 (12%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM 61 + + + + ++L + +I GD + + I +G+ I ++ D Sbjct: 150 ILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRC 209 Query: 62 IIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTL 121 + Y N G FGEL L ++A + A + + FR + + Sbjct: 210 VGNYDNRGS-FGELALMY----NTPKAATITATSPGALWGLDRVTFRRI----------I 254 Query: 122 GSQMADRLRKTTRKVGDLAF---LDVTGRV 148 A + + + L F L+V+ R+ Sbjct: 255 VKNNAKKRKMYESFIESLPFLKSLEVSERL 284 >6FTF-B nrPDB Length = 304 Score = 56.6 bits (135), Expect = 8e-09, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 39/96 (40%), Gaps = 4/96 (4%) Query: 25 YTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSE 84 ++ II+ G+ E L+ I++G+V ++ D DG + GD GEL + Sbjct: 186 FSPGEYIIHYGEEGEWLYIIMEGTVEVIGRDADGEPTKVCEFTQGDHIGELEFL----NN 241 Query: 85 QERSAWVRAKVECEVAEISYAKFRELSQQDSEILYT 120 A V A A+++ F ++L Sbjct: 242 HRTVADVVATTHVITAKLNRRHFEMCLGPVIDVLKR 277 >4ORF-A nrPDB Length = 340 Score = 53.2 bits (126), Expect = 8e-08, Method: Composition-based stats. Identities = 22/129 (17%), Positives = 37/129 (28%), Gaps = 6/129 (4%) Query: 2 VAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM 61 + + L+ L + +I GD T I G V + DG + Sbjct: 22 LEFFTGCRPSALEPLATQLRPLKAEPGQVLIRQGDPALTFMLIESGRVQVSHAVADGPPI 81 Query: 62 IIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTL 121 ++ G GE+ L + ++A V A F + + L Sbjct: 82 VLDI-EPGLIIGEIALLR----DAPKTATVVAAEPVIGWVGDRDAFDTILH-LPGMFDRL 135 Query: 122 GSQMADRLR 130 RL Sbjct: 136 VRIARQRLA 144 >4MGY-E nrPDB Length = 694 Score = 50.5 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 45/117 (38%), Gaps = 15/117 (12%) Query: 4 ITHTPKLKHLDKLLAH------CHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDD 57 + H L HL + + + G+ + + I+KGSV ++I Sbjct: 34 LLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKG 93 Query: 58 GREMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVE-CEVAEISYAKFRELSQQ 113 ++ L+ GD FG+L L ++ R+A + + + C + F + + Sbjct: 94 ----VVCTLHEGDDFGQLALV----NDAPRAASIVLREDNCHFLRVDKEDFNRILRD 142 >1O7F-A nrPDB Length = 469 Score = 50.5 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 45/117 (38%), Gaps = 15/117 (12%) Query: 4 ITHTPKLKHLDKLLAH------CHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDD 57 + H L HL + + + G+ + + I+KGSV ++I Sbjct: 339 LLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKG 398 Query: 58 GREMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVE-CEVAEISYAKFRELSQQ 113 ++ L+ GD FG+L L ++ R+A + + + C + F + + Sbjct: 399 ----VVCTLHEGDDFGKLALV----NDAPRAASIVLREDNCHFLRVDKEDFNRILRD 447 Score = 47.4 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 35/102 (34%), Gaps = 7/102 (6%) Query: 24 RYTAKSTIIYAGDRCETLFFIIKGS--VTILIEDDDGREMIIGYLNSGDFFGELGLFEKE 81 T+ GD + ++ GS V + + I L G FGE L Sbjct: 69 NLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESIL---- 124 Query: 82 GSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 R A + + E+ I F+ L ++ + + L + Sbjct: 125 -DNTPRHATIVTRESSELLRIEQEDFKALWEKYRQYMAGLLA 165 >4F7Z-A nrPDB Length = 999 Score = 47.8 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 35/102 (34%), Gaps = 7/102 (6%) Query: 24 RYTAKSTIIYAGDRCETLFFIIKGS--VTILIEDDDGREMIIGYLNSGDFFGELGLFEKE 81 T+ GD + ++ GS V + + I L G FGE L Sbjct: 69 NLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESIL---- 124 Query: 82 GSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGS 123 R A + + E+ I F+ L ++ + + L + Sbjct: 125 -DNTPRHATIVTRESSELLRIEQEDFKALWEKYRQYMAGLLA 165 Score = 47.4 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 21/117 (17%), Positives = 44/117 (37%), Gaps = 15/117 (12%) Query: 4 ITHTPKLKHLDKLLAH------CHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDD 57 + H L HL + + + G+ + + I+KGSV ++I Sbjct: 339 LLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKG 398 Query: 58 GREMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVE-CEVAEISYAKFRELSQQ 113 ++ L+ GD FG+L L ++ R+A + + + C + + + Sbjct: 399 ----VVCTLHEGDDFGKLALV----NDAPRAASIVLREDNCHFLRVDKEDGNRILRD 447 >4AVC-A nrPDB Length = 333 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 35/115 (30%), Gaps = 6/115 (5%) Query: 16 LLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGEL 75 L A R A ++ G+ + I GS + DDG +I L G GE+ Sbjct: 32 LAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEVSHVGDDGVAIIARAL-PGMIVGEI 90 Query: 76 GLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLR 130 L + RSA V F + + L RL Sbjct: 91 ALLR----DSPRSATVTTIEPLTGWTGGRGAFATMVHI-PGVGERLLRTARQRLA 140 >2D93-A nrPDB Length = 134 Score = 32.4 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 37/88 (42%), Gaps = 10/88 (11%) Query: 26 TAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEKEGSEQ 85 A + I+ G ++ + I+ G+V I DG+ + L G+ FG +K+ Sbjct: 46 QAGAIILEDGQELDSWYVILNGTVEIS--HPDGK---VENLFMGNSFGITPTLDKQYM-- 98 Query: 86 ERSAWVRAKV-ECEVAEISYAKFRELSQ 112 VR KV +C+ I+ + + Sbjct: 99 --HGIVRTKVDDCQFVCIAQQDYWRILN 124 >5W1E-A nrPDB Length = 526 Score = 32.4 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Query: 160 DAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVV 210 +T DG + ++ + R G +R V R+ +L G V + G+ +V+ Sbjct: 28 GRLTGADGGTLSLS--ALERTTGLARSTVDRLTATLARMGYVRLDGRDVVL 76 >4L5I-A nrPDB Length = 318 Score = 32.4 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 20/33 (60%) Query: 172 ITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVK 204 +T+ EI +G +R V R+L+ + G++ V+ Sbjct: 32 LTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQ 64 >2W48-A nrPDB Length = 315 Score = 32.4 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 20/33 (60%) Query: 171 KITRQEIGRIVGCSREMVGRVLKSLEEQGLVHV 203 +T+ +I R +G R + R+LK EQG+V + Sbjct: 21 DMTQAQIARELGIYRTTISRLLKRGREQGIVTI 53 >3E3M-A nrPDB Length = 355 Score = 29.7 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 8/24 (33%), Positives = 13/24 (54%) Query: 171 KITRQEIGRIVGCSREMVGRVLKS 194 +T +++ + G SR V R LK Sbjct: 12 PVTMRDVAKAAGVSRMTVSRALKK 35 >5TRD-A nrPDB Length = 230 Score = 28.9 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 18/33 (54%) Query: 171 KITRQEIGRIVGCSREMVGRVLKSLEEQGLVHV 203 +T ++ ++G S++ R++ LE+ G + Sbjct: 27 YLTSSKLADMLGISQQSASRIIIDLEKNGYITR 59 >4C0Q-A nrPDB Length = 923 Score = 28.9 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 22/53 (41%), Gaps = 1/53 (1%) Query: 116 EILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQ-QPDAMTHPDG 167 EI + ++ + L KT +V F R+ L CQ +PD P+ Sbjct: 340 EISFNFWYRLGEHLYKTNDEVIHGIFKAYIQRLLHALARHCQLEPDHEGVPEE 392 >1V4R-A nrPDB Length = 102 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 20/47 (42%), Gaps = 1/47 (2%) Query: 165 PDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVF 211 G + + +I G + + V R L L+ +GLV +G V Sbjct: 30 APGDTLP-SVADIRAQFGVAAKTVSRALAVLKSEGLVSSRGALGTVV 75 >3TGN-A nrPDB Length = 146 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 28/64 (43%), Gaps = 6/64 (9%) Query: 150 RTLLDLCQQPDAMTHPDGMQI------KITRQEIGRIVGCSREMVGRVLKSLEEQGLVHV 203 L+ C A+T+ + +T E+ R + S+ V + +KSL ++G++ Sbjct: 24 EILIGHCTSEVALTNTQEHILMLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLET 83 Query: 204 KGKT 207 + Sbjct: 84 SKDS 87 >5WHM-A nrPDB Length = 267 Score = 28.5 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 9/55 (16%), Positives = 20/55 (36%) Query: 150 RTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVK 204 + + L + + + + + QEI G + V R+ +L G + Sbjct: 21 QFVTALARGLEVLRCFTPTENTLGNQEIAHKTGLPKPTVSRLTHTLVRLGYLRQD 75 >2XRN-A nrPDB Length = 241 Score = 28.1 bits (61), Expect = 3.1, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 172 ITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKG 205 ++ I ++VG R V R++ +LEE+ LV G Sbjct: 22 LSLAAIAQLVGLPRSTVQRIINALEEEFLVEALG 55 >5LOJ-A nrPDB Length = 263 Score = 28.1 bits (61), Expect = 3.3, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 20/43 (46%), Gaps = 5/43 (11%) Query: 177 IGRIVGCSREMVGRVLKSLEEQGLVH-----VKGKTMVVFGTR 214 I VG +R ++ L+ LE G++ +KG + V + Sbjct: 205 IADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNNK 247 >3F8M-A nrPDB Length = 248 Score = 27.7 bits (60), Expect = 3.7, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 3/61 (4%) Query: 154 DLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGT 213 +L + D M D +EI +RE V + L+ L G V +G+T VV Sbjct: 22 ELDRMLDGMRIGDPFP---AEREIAEQFEVARETVRQALRELLIDGRVERRGRTTVVARP 78 Query: 214 R 214 + Sbjct: 79 K 79 >2DBB-A nrPDB Length = 151 Score = 27.7 bits (60), Expect = 3.7, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 20/33 (60%) Query: 171 KITRQEIGRIVGCSREMVGRVLKSLEEQGLVHV 203 ++T +E+ I+ +R+ + R + L++ G++ Sbjct: 23 RLTYRELADILNTTRQRIARRIDKLKKLGIIRK 55 >6J1O-A nrPDB Length = 387 Score = 27.7 bits (60), Expect = 3.9, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 18/31 (58%) Query: 171 KITRQEIGRIVGCSREMVGRVLKSLEEQGLV 201 + +E+ +GC RE++ R+L+ + +V Sbjct: 75 PQSAEELADHLGCGRELMSRLLRYMASVRMV 105 >3H5O-A nrPDB Length = 339 Score = 27.7 bits (60), Expect = 4.1, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 13/27 (48%) Query: 168 MQIKITRQEIGRIVGCSREMVGRVLKS 194 M + +T ++ + G S V RVL Sbjct: 1 MSLGVTMHDVAKAAGVSAITVSRVLNQ 27 >2B0L-A nrPDB Length = 102 Score = 27.4 bits (59), Expect = 4.4, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 20/43 (46%), Gaps = 5/43 (11%) Query: 177 IGRIVGCSREMVGRVLKSLEEQGLVH-----VKGKTMVVFGTR 214 I VG +R ++ L+ LE G++ +KG + V + Sbjct: 49 IADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNNK 91 >4L9V-A nrPDB Length = 145 Score = 27.4 bits (59), Expect = 4.6, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 32/83 (38%), Gaps = 13/83 (15%) Query: 120 TLGSQMADRLRK-TTRKVGDLAFLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIG 178 L ++ +++ +K+ L + G L Q +T+ +I Sbjct: 7 YLFRMISHEMKQKADQKLEQLDITNEQGHTLGYLYAHQQDG------------LTQNDIA 54 Query: 179 RIVGCSREMVGRVLKSLEEQGLV 201 + + + V +L++LE + L+ Sbjct: 55 KALQRTGPTVSNLLRNLERKKLI 77 >5E4R-A nrPDB Length = 490 Score = 27.4 bits (59), Expect = 5.2, Method: Composition-based stats. Identities = 25/164 (15%), Positives = 61/164 (37%), Gaps = 10/164 (6%) Query: 60 EMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILY 119 E D FGE + E ++++ E E++Y + + +++Y Sbjct: 181 ESTFKEETETDLFGEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIY 240 Query: 120 T-----LGSQMADRLRKTTRKVGD-LAFLDVTGRVARTLLDLCQQPDAMTH---PDGMQI 170 + ++D + VG + V ++ + +L+ + + + Sbjct: 241 EKGLTGMLRAVSDTAKYGGITVGKFIIDKSVRDKM-KIVLERIRSGEFAREWIKEYERGM 299 Query: 171 KITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR 214 +E+ + G + E VGR L+ + +G+ + +FG + Sbjct: 300 PTVFKELSELEGSTIETVGRKLREMMFRGMKQISSHETDLFGEQ 343 >1QBJ-A nrPDB Length = 81 Score = 27.4 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 28/67 (41%), Gaps = 11/67 (16%) Query: 141 FLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGL 200 + D R+ + L +L + H ++ +G ++ + RVL SL ++G Sbjct: 8 YQDQEQRILKFLEELGEGKATTAH-----------DLSGKLGTPKKEINRVLYSLAKKGK 56 Query: 201 VHVKGKT 207 + + T Sbjct: 57 LQKEAGT 63 >4XDZ-A nrPDB Length = 343 Score = 26.6 bits (57), Expect = 7.5, Method: Composition-based stats. Identities = 23/150 (15%), Positives = 56/150 (37%), Gaps = 10/150 (6%) Query: 60 EMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILY 119 E D FGE + E ++++ E E++Y + + +++Y Sbjct: 181 ESTFKEETETDLFGEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIY 240 Query: 120 T-----LGSQMADRLRKTTRKVGD-LAFLDVTGRVARTLLDLCQQPDAMTH---PDGMQI 170 + ++D + VG + V ++ + +L+ + + + Sbjct: 241 EKGLTGMLRAVSDTAKYGGITVGKFIIDKSVRDKM-KIVLERIRSGEFAREWIKEYERGM 299 Query: 171 KITRQEIGRIVGCSREMVGRVLKSLEEQGL 200 +E+ + G + E VGR L+ + +G+ Sbjct: 300 PTVFKELSELEGSTIETVGRKLREMMFRGM 329 >2UWM-A nrPDB Length = 258 Score = 26.6 bits (57), Expect = 7.5, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 40/105 (38%), Gaps = 6/105 (5%) Query: 94 KVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLL 153 +VE ++ IS +++ Q + L S+ R ++ F + RV + LL Sbjct: 51 RVENDLYAISTERYQAWWQAVTRALEEFHSRYPLRPGLAREELRSRYFSRLPARVYQALL 110 Query: 154 DLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQ 198 + + + Q+ + E ++LK LE++ Sbjct: 111 EEWSREGRL------QLAANTVALAGFTPSFSETQKKLLKDLEDK 149 >1UXV-A nrPDB Length = 501 Score = 26.6 bits (57), Expect = 7.5, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 19/45 (42%) Query: 155 LCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQG 199 L + ++ I I +++ SRE V R L L ++G Sbjct: 23 LAGEWGGSGQEIEVKSPIDLATIAKVISPSREEVERTLDVLFKRG 67 >2L54-A nrPDB Length = 63 Score = 26.6 bits (57), Expect = 7.6, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 28/67 (41%), Gaps = 11/67 (16%) Query: 141 FLDVTGRVARTLLDLCQQPDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGL 200 + D R+ + L +L + H ++ +G ++ + RVL SL ++G Sbjct: 1 YQDQEQRILKFLEELGEGKATTAH-----------DLSGKLGTPKKEIARVLASLAKKGK 49 Query: 201 VHVKGKT 207 + + T Sbjct: 50 LQKEAGT 56 >2H09-A nrPDB Length = 155 Score = 26.6 bits (57), Expect = 7.9, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 16/28 (57%) Query: 176 EIGRIVGCSREMVGRVLKSLEEQGLVHV 203 ++ +G S+ V ++LK L GL+ + Sbjct: 59 DMAARLGVSQPTVAKMLKRLATMGLIEM 86 >5TJJ-A nrPDB Length = 260 Score = 26.6 bits (57), Expect = 8.1, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 17/32 (53%) Query: 176 EIGRIVGCSREMVGRVLKSLEEQGLVHVKGKT 207 EI +G ++ RVL++LE + V ++ Sbjct: 33 EIAERLGVNKTTCLRVLRTLEREDFVSYDPQS 64 >4AIH-A nrPDB Length = 151 Score = 26.6 bits (57), Expect = 8.4, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 30/66 (45%), Gaps = 8/66 (12%) Query: 147 RVARTLLDLCQQPDAMTHPDGMQIK--------ITRQEIGRIVGCSREMVGRVLKSLEEQ 198 RV R L+D +P +T + + ++ ++ + +G + + R L LEE+ Sbjct: 14 RVWRALIDHRLKPLELTQTHWVTLYNINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEK 73 Query: 199 GLVHVK 204 GL+ Sbjct: 74 GLITRH 79 >1OSL-A nrPDB Length = 62 Score = 26.6 bits (57), Expect = 8.6, Method: Composition-based stats. Identities = 6/24 (25%), Positives = 11/24 (45%) Query: 171 KITRQEIGRIVGCSREMVGRVLKS 194 +T ++ G S + V RV+ Sbjct: 3 PVTLYDVAEYAGVSYQTVSRVVNQ 26 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.316 0.132 0.297 Lambda K H 0.267 0.0403 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,370,788 Number of Sequences: 36641 Number of extensions: 218220 Number of successful extensions: 1100 Number of sequences better than 10.0: 113 Number of HSP's better than 10.0 without gapping: 135 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 829 Number of HSP's gapped (non-prelim): 205 length of query: 214 length of database: 10,336,785 effective HSP length: 93 effective length of query: 121 effective length of database: 6,929,172 effective search space: 838429812 effective search space used: 838429812 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 57 (26.6 bits)