BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P55084 (474 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5ZQZ-B nrPDB 980 0.0 3SS6-A nrPDB 212 3e-55 1ULQ-A nrPDB 204 8e-53 2IIK-A nrPDB 203 1e-52 4NZS-A nrPDB 203 2e-52 3GOA-A nrPDB 202 2e-52 5CBQ-A nrPDB 201 4e-52 4DD5-A nrPDB 201 5e-52 5LP7-H nrPDB 201 6e-52 4C2K-A nrPDB 201 6e-52 1WDK-C nrPDB 200 9e-52 4N44-A nrPDB 200 9e-52 6BN2-A nrPDB 196 2e-50 6ARG-A nrPDB 194 7e-50 4E1L-A nrPDB 193 2e-49 2IBU-A nrPDB 186 3e-47 1NL7-A nrPDB 185 3e-47 2C7Y-A nrPDB 178 5e-45 5XYJ-B nrPDB 174 6e-44 2WUA-A nrPDB 168 5e-42 1WL4-A nrPDB 166 2e-41 4WYS-A nrPDB 166 3e-41 4O9A-A nrPDB 162 2e-40 1PXT-A nrPDB 158 5e-39 6BJB-A nrPDB 155 2e-38 4UBW-A nrPDB 151 5e-37 3SVK-A nrPDB 140 1e-33 6BJA-A nrPDB 137 8e-33 4B3J-C nrPDB 131 5e-31 5LNQ-A nrPDB 49 4e-06 4YZO-A nrPDB 47 3e-05 4BI9-A nrPDB 47 3e-05 6ESQ-A nrPDB 42 8e-04 6HRV-A nrPDB 40 0.001 3KZU-A nrPDB 37 0.016 6QSP-A nrPDB 36 0.028 4U4E-A nrPDB 35 0.075 5M3K-C nrPDB 35 0.084 3E60-A nrPDB 35 0.084 2IWZ-A nrPDB 34 0.12 4JPF-A nrPDB 33 0.30 1J3N-A nrPDB 32 0.41 3PND-A nrPDB 32 0.84 4XGV-A nrPDB 31 0.97 4JGA-A nrPDB 30 1.9 6ET0-A nrPDB 30 2.1 3VWB-A nrPDB 30 2.5 4QAV-A nrPDB 30 2.6 2IX4-A nrPDB 30 2.7 4DDO-A nrPDB 30 2.9 3LGS-A nrPDB 29 3.9 3HHE-A nrPDB 29 4.0 2GP6-A nrPDB 29 4.2 1JPU-A nrPDB 29 5.2 5BQS-A nrPDB 29 5.4 3IL7-A nrPDB 29 5.6 1QN4-A nrPDB 28 6.8 4EWP-A nrPDB 28 9.6 >5ZQZ-B nrPDB Length = 474 Score = 980 bits (2533), Expect = 0.0, Method: Compositional matrix adjust. Identities = 474/474 (100%), Positives = 474/474 (100%) Query: 1 MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGV 60 MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGV Sbjct: 1 MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGV 60 Query: 61 RTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAA 120 RTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAA Sbjct: 61 RTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAA 120 Query: 121 LGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMR 180 LGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMR Sbjct: 121 LGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMR 180 Query: 181 KLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLE 240 KLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLE Sbjct: 181 KLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLE 240 Query: 241 QDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPY 300 QDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPY Sbjct: 241 QDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPY 300 Query: 301 GTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATP 360 GTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATP Sbjct: 301 GTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATP 360 Query: 361 KVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNW 420 KVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNW Sbjct: 361 KVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNW 420 Query: 421 GGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK 474 GGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK Sbjct: 421 GGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK 474 >3SS6-A nrPDB Length = 394 Score = 212 bits (539), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 150/428 (35%), Positives = 216/428 (50%), Gaps = 45/428 (10%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 + NVV+ VR+P G + K++ P +LA L + R V VD +I G IQ Sbjct: 4 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRT 63 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 +N AR AAL AGF D +T+ C S QA+ + I G +V+VAGGVE MS Sbjct: 64 DEANTARTAALAAGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGVEAMSS 123 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSL--ISKFRFNFLAPELPAVSEFSTSETMGHSAD 228 P ++ K + GQRL I + L + + MG +A+ Sbjct: 124 SP--YALKQHR----------WGQRLQHGEIRDTVWEVLEDPIHHI-------MMGETAE 164 Query: 229 RLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPG--KDTV-TKDNGIRPS 284 L + ++R EQDE ALRSH+LA KA + G D +VP + K+ V +KD R Sbjct: 165 NLVEQYEITREEQDEVALRSHTLALKAIESGYFDDQIVPITIKERRKEVVFSKDEHPRAD 224 Query: 285 -SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYV 343 + E++A LKPAF K G+VTA N+S L DG++ +++M+EEKA G +P A + + Sbjct: 225 ITAEKLAGLKPAFRKD-GSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVA 283 Query: 344 SQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYM 403 DPK + +GP A K LEK ++ D D E +EAF+ Q LA K +D D Sbjct: 284 GVDPK-IMGIGPAPAIRKGLEKVDWSLEDADLLEINEAFAAQYLAVEKELDLD------- 335 Query: 404 GRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQ 463 EK N G + LGHP G TG R+ ++ + L++ G + G+ + C GG Sbjct: 336 ----------REKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGI 385 Query: 464 GHAMIVEA 471 G A+ +EA Sbjct: 386 GVALFIEA 393 >1ULQ-A nrPDB Length = 401 Score = 204 bits (518), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 147/421 (34%), Positives = 222/421 (52%), Gaps = 34/421 (8%) Query: 56 VVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS-N 114 +V+ VRTP G + + P DL AL+ L+ R+ VPKE V+ + G Q + + N Sbjct: 6 IVEAVRTPIGKHGGALASVRPDDLLAHALSVLVDRSGVPKEEVEDVYAGCANQAGEDNRN 65 Query: 115 VAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIR 174 VAR A L AGF + TV C S +A+ I +G+ V + GVE MS P Sbjct: 66 VARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVESMSRAPYA 125 Query: 175 HSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAF 234 + R G + + + F+ P++ A +E+MG +A+ LA + Sbjct: 126 VPKPERGF--------PTGNLVMYDTTLGWRFVNPKMQA---LYGTESMGETAENLAEMY 174 Query: 235 AVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP-GKDT--VTKDNG-IRPSSLEQM 289 + R EQD +AL SH A +A +EG D VVP V GK+ V +D G R +SLE++ Sbjct: 175 GIRREEQDRFALLSHQKAVRAWEEGRFQDEVVPVPVKRGKEEILVEQDEGPRRDTSLEKL 234 Query: 290 AKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKD 349 A L+P F + GTVTA NSS L DGA+A+L+++++ A A G +P A +R + V+ P Sbjct: 235 AALRPVF-REGGTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVR-AIAVAGVPPR 292 Query: 350 QLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKV 409 + +GP AT K LE+AGL+ +D+ E +EAF+ Q LA + +W Sbjct: 293 IMGIGPVPATRKALERAGLSFSDLGLIELNEAFAAQALAVLR----EWSLSMED------ 342 Query: 410 GLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIV 469 ++ N GG+++LGHP GA+G R++ + +R+ Q+GL C GQG A++V Sbjct: 343 -----QRLNPNGGAIALGHPLGASGARILTTLVHEMRRRKVQFGLATMCIGVGQGIAVVV 397 Query: 470 E 470 E Sbjct: 398 E 398 >2IIK-A nrPDB Length = 418 Score = 203 bits (517), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 153/433 (35%), Positives = 221/433 (51%), Gaps = 59/433 (13%) Query: 53 NVVVVDGVRTPFLLSGTS-YKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVK 111 +VVVV G RT +G +KD P +L A +T +L ++ E + I G V+Q Sbjct: 31 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 90 Query: 112 TSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDV 171 + +AR A + + P TV C S QA+ + G I +G D+ +A GVE MS Sbjct: 91 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS-- 148 Query: 172 PIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLA 231 + D ++ RL K R + L P MG +++ +A Sbjct: 149 -----------LADRGNPGNITSRLMEKEKAR-DCLIP-------------MGITSENVA 183 Query: 232 AAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKD--------TVTKDNGIR 282 F +SR +QD +AL S A +AQ +G +++VP D TVT+D GIR Sbjct: 184 ERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIR 243 Query: 283 PS-SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFM 341 PS ++E +AKLKPAF K G+ TA NSS ++DGA+A+L+ KA +G LR + Sbjct: 244 PSTTMEGLAKLKPAF-KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYA 302 Query: 342 YVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAEN 401 V P D + +GP YA P L+KAGLT++D+D FE +EAF+ Q + + E Sbjct: 303 VVGV-PPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQ---------AAYCVE- 351 Query: 402 YMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQ-YGLVAACAA 460 K+ LPP EK N GG+++LGHP G TG R V+ N L++ G + YG+V+ C Sbjct: 352 ------KLRLPP-EKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIG 404 Query: 461 GGQGHAMIVEAYP 473 G G A + E YP Sbjct: 405 TGMGAAAVFE-YP 416 >4NZS-A nrPDB Length = 399 Score = 203 bits (516), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 151/425 (35%), Positives = 207/425 (48%), Gaps = 41/425 (9%) Query: 52 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQ-EV 110 R VVVV GVRT G S KD+ P +L + L R V + V +++FG VIQ E Sbjct: 8 REVVVVSGVRTAIGTFGGSLKDVAPAELGALVVREALARAQVSGDDVGHVVFGNVIQTEP 67 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 + + R AA+ G + PA TV C S QA+ + I G DV + GG E MS Sbjct: 68 RDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAESMSR 127 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 P L A G R+ + L A+ + MG +A+ + Sbjct: 128 APY------------LAPAARWGARMG-----DAGLVDMMLGALHDPFHRIHMGVTAENV 170 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---TVTKDNGIR-PSS 285 A + +SR +QDE AL SH A A G D +VP G+ T D +R ++ Sbjct: 171 AKEYDISRAQQDEAALESHRRASAAIKAGYFKDQIVPVVSKGRKGDVTFDTDEHVRHDAT 230 Query: 286 LEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQ 345 ++ M KL+P F+K GTVTA N+S L D A+A+++M +A G KP A L + + Sbjct: 231 IDDMTKLRPVFVKENGTVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGV 290 Query: 346 DPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGR 405 DPK + +GP AT LE+AGL ++D+D E +EAF+ Q A KA+ Sbjct: 291 DPK-AMGIGPVPATKIALERAGLQVSDLDVIEANEAFAAQACAVTKAL------------ 337 Query: 406 KTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGH 465 GL P K N G +SLGHP GATG + + A + L + G+Y LV C GGQG Sbjct: 338 ----GLDP-AKVNPNGSGISLGHPIGATGALITVKALHELNRVQGRYALVTMCIGGGQGI 392 Query: 466 AMIVE 470 A I E Sbjct: 393 AAIFE 397 >3GOA-A nrPDB Length = 387 Score = 202 bits (515), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 147/429 (34%), Positives = 215/429 (50%), Gaps = 53/429 (12%) Query: 51 IRNVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHRT-SVPKEVVDYIIFGTVIQ 108 + VV+VD +RTP S G +++++ DL+ + LL R S+ +D I +G V Q Sbjct: 1 MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQ 60 Query: 109 EVKTS-NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167 ++ N+AR AAL A PA TV C S+ QA+ +I +G V + GGVE Sbjct: 61 TLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEH 120 Query: 168 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227 M VP+ H L N AK+ G MG +A Sbjct: 121 MGHVPMSHGVDFHP-GLSRNVAKAAGM----------------------------MGLTA 151 Query: 228 DRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKDTVTK----DNGIR 282 + L+ +SR QD++A RSH+ A A G ++++P D V K D IR Sbjct: 152 EMLSRLHGISREMQDQFAARSHARAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIR 211 Query: 283 P-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFM 341 P +++E ++ L+PAF GTVTA SS L+DGA+AML+M+E +A +G KP+A +R Sbjct: 212 PETTVEALSTLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMA 271 Query: 342 YVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAEN 401 V DP + GP A+ L+KAGL+ +DID FE +EAF+ QIL K Sbjct: 272 VVGCDPS-IMGYGPVPASKLALKKAGLSASDIDVFEMNEAFAAQILPCIK---------- 320 Query: 402 YMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAG 461 +G ++ EK N GG+++LGHP G +G R+ N + ++ Q+GL C Sbjct: 321 DLGLMEQID----EKINLNGGAIALGHPLGCSGARISTTLINLMERKDAQFGLATMCIGL 376 Query: 462 GQGHAMIVE 470 GQG A + E Sbjct: 377 GQGIATVFE 385 >5CBQ-A nrPDB Length = 413 Score = 201 bits (512), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 150/432 (34%), Positives = 213/432 (49%), Gaps = 42/432 (9%) Query: 50 NIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQE 109 ++R+ V+ + VRTP G ++ L DL AL GLL RT + + V+ +I G Sbjct: 8 SMRDAVICEPVRTPIGRYGGMFRSLTAVDLGVTALKGLLERTGIAADQVEDVILGHCYPN 67 Query: 110 VKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 + + R AL AG P V C S QA+ + SG D++VAGG E MS Sbjct: 68 SEAPAIGRVVALDAGLPITVPGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAESMS 127 Query: 170 DVPIRHSRKMR----KLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGH 225 +V +S MR + + ++ + G R + KF +P M Sbjct: 128 NVAF-YSTDMRWGGARTGVQIHDGLARG-RTTAGGKFH------PVPG--------GMLE 171 Query: 226 SADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKV---PGKDTVTKDNGI 281 +A+ L + +SR EQDE A+RSH A AQ EG+L++ ++P V G++T++ D Sbjct: 172 TAENLRREYHISRTEQDELAVRSHQRAVAAQSEGVLAEEIIPVPVRTRDGEETISVDEHP 231 Query: 282 RP-SSLEQMAKLKPAFIK--PYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLR 338 R +++E +AKLKP +K P TVTA NSS D AS ++ EKA +G KP L Sbjct: 232 RADTTVEALAKLKPVLLKQDPEATVTAGNSSGQNDAASMCIVTTPEKAAELGLKPLVRLV 291 Query: 339 DFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWF 398 + P D + +GP AT L KAGLT+ DID E +EAF+ Q LA + +W Sbjct: 292 SWGSAGVAP-DLMGIGPVPATEVALAKAGLTLADIDLIELNEAFAAQALAVMR----EW- 345 Query: 399 AENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAAC 458 K G E+ N G +SLGHP GATG R++ A L + +YGL C Sbjct: 346 ---------KFGEADHERTNVRGSGISLGHPVGATGGRMLATLARELHRREARYGLETMC 396 Query: 459 AAGGQGHAMIVE 470 GGQG A + E Sbjct: 397 IGGGQGLAAVFE 408 >4DD5-A nrPDB Length = 396 Score = 201 bits (511), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 137/426 (32%), Positives = 222/426 (52%), Gaps = 40/426 (9%) Query: 50 NIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQE 109 N+R VV+ RT G ++K + +L A + R ++ +++D + G V+ Sbjct: 5 NMREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANITPDMIDESLLGGVLTA 64 Query: 110 VKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 N+AR+ ALGAG + PA T+ + C S ++++ LIA G D+++ GG E MS Sbjct: 65 GLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGAENMS 124 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 P L+ MG + S + +S+ + MG +A+ Sbjct: 125 MSPY--------LVPSARYGARMGDAAFVDSMIK--------DGLSDIFNNYHMGITAEN 168 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGK--DTVT-KDNGIRP-S 284 +A + ++R EQDE AL S + A+KAQ EG ++VP + G+ DTV KD I+P + Sbjct: 169 IAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEYIKPGT 228 Query: 285 SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS 344 ++E++AKL+PAF K GTVTA N+S + DGA+ +++MA+EKA +G +P A + + Sbjct: 229 TMEKLAKLRPAF-KKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAG 287 Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMG 404 DPK + GP AT K LE A +T+ DID E +EAF+ Q +A + ++ D Sbjct: 288 VDPK-IMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNID-------- 338 Query: 405 RKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQG 464 + K N GG++++GHP G +G R++ +++ + GL C GG G Sbjct: 339 ---------MNKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMG 389 Query: 465 HAMIVE 470 +IV+ Sbjct: 390 TTLIVK 395 >5LP7-H nrPDB Length = 393 Score = 201 bits (511), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 142/428 (33%), Positives = 216/428 (50%), Gaps = 41/428 (9%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 +R V+V RTPF G K++ +L + L + V + V+ + G V+Q Sbjct: 1 MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQQAGVSGDDVEGNVMGMVVQAG 60 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 +R+AA AG P+ T+ C S +A+T +I + D++VAGG+E MS+ Sbjct: 61 SGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGMESMSN 120 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 +P A G R+ + R + L + G++A Sbjct: 121 IPYAVP------------AGRWGARMG-DGELRDLMVYDGLTCAFDEVHMAVHGNTA--- 164 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGK----DTVTKDNGIR-PS 284 A +A+SR EQDE+ALRSH+ A KA DEG D +VP G+ + V KD IR + Sbjct: 165 AKEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRRDT 224 Query: 285 SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS 344 SL+Q+AKL P + G++TA N+ + DGA A ++M+EEKA +G +P A + F Sbjct: 225 SLDQLAKLAPIYASD-GSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFSTTG 283 Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMG 404 P +L P +A K+L+K GLT+ DID FE +EAF+ +L K + D Sbjct: 284 M-PAHELAAAPGFAINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFD-------- 334 Query: 405 RKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQG 464 LEK N GG+++LGHP GA+G R++M L++ GG G+ A C+ QG Sbjct: 335 ---------LEKVNVNGGAIALGHPIGASGARILMTLVYELKRRGGGLGVAAICSGAAQG 385 Query: 465 HAMIVEAY 472 A++V+ + Sbjct: 386 DAVLVQVH 393 >4C2K-A nrPDB Length = 417 Score = 201 bits (511), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 146/429 (34%), Positives = 214/429 (49%), Gaps = 45/429 (10%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 +R V VV RTPF G KD DL+ A L V E VD +I G V+Q Sbjct: 24 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 83 Query: 111 KTS-NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 + +AR L G +TPA T+ C S Q++ G I + +V++ GG E MS Sbjct: 84 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 143 Query: 170 DVP--IRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227 P +R+ R KL D+ S+ +SL + +LP M +A Sbjct: 144 QAPYCVRNVRFGTKLGSDIKLEDSL--WVSLTDQH------VQLP----------MAMTA 185 Query: 228 DRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP---GKDTVTKDNGIRP 283 + LA +SR E D+YAL+S K A D G +D + P +V GK T+ D RP Sbjct: 186 ENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARP 245 Query: 284 -SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMY 342 ++LEQ+ KL P F K GTVTA N+S + DGA A++I +E+ + P A + + Sbjct: 246 QTTLEQLQKLPPVF-KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFV 304 Query: 343 VSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENY 402 DP + +GP A L+KAGL++ D+D E +EAF+ Q LA +++D D Sbjct: 305 SGCDP-SIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLD------ 357 Query: 403 MGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGG 462 + K N GG+++LGHP G +G R+ + LR+ GG+Y + +AC GG Sbjct: 358 -----------ISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGG 406 Query: 463 QGHAMIVEA 471 QG A+I+++ Sbjct: 407 QGIAVIIQS 415 >1WDK-C nrPDB Length = 390 Score = 200 bits (509), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 152/436 (34%), Positives = 220/436 (50%), Gaps = 65/436 (14%) Query: 50 NIRNVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHRTSV--PKEVVDYIIFGTV 106 N R+VV+VD RTP S G +++ D++ ++ +L R S P EV D +I+G V Sbjct: 3 NPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVED-VIWGCV 61 Query: 107 IQEVKTS-NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGV 165 Q ++ N+AR A+L + A TV+ C S+ A+ T I +G DV V GGV Sbjct: 62 NQTLEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGV 121 Query: 166 ELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFST--SETM 223 E M V + H +D N P +S ++ S M Sbjct: 122 EHMGHVSMMHG-------VDPN------------------------PHMSLYAAKASGMM 150 Query: 224 GHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKDTVTK----D 278 G +A+ L +SR +QD +A+RSH LA KA EG D ++P + ++ K D Sbjct: 151 GLTAEMLGKMHGISREQQDAFAVRSHQLAHKATVEGKFKDEIIPMQGYDENGFLKIFDYD 210 Query: 279 NGIRP-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYL 337 IRP ++LE +A LKPAF GTVTA SS +TDGAS M++M+ ++A +G +P A + Sbjct: 211 ETIRPDTTLESLAALKPAFNPKGGTVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVI 270 Query: 338 RDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQ---ILANFKAMD 394 R DP + GP AT K L++AGL M DID E +EAF+ Q +L + K +D Sbjct: 271 RSMAVAGVDPA-IMGYGPVPATQKALKRAGLNMADIDFIELNEAFAAQALPVLKDLKVLD 329 Query: 395 SDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGL 454 K+ EK N GG+++LGHPFG +G R+ N +++ GG +GL Sbjct: 330 -------------KMN----EKVNLHGGAIALGHPFGCSGARISGTLLNVMKQNGGTFGL 372 Query: 455 VAACAAGGQGHAMIVE 470 C GQG A + E Sbjct: 373 STMCIGLGQGIATVFE 388 >4N44-A nrPDB Length = 400 Score = 200 bits (509), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 145/427 (33%), Positives = 220/427 (51%), Gaps = 44/427 (10%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 ++ VV+ VRT G S KD+ DL A+ + + + E V+ +I G V+Q Sbjct: 1 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAG 60 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 N AR+A+ AG + PA T+ C S + ++ +I +G DVI+AGG+E MS Sbjct: 61 LGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSR 120 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPEL-PAVSEFSTSETMGHSADR 229 P L G R+ +KF + L A +++ MG +A+ Sbjct: 121 APY------------LANNARWGYRMGN-AKFVDEMITDGLWDAFNDYH----MGITAEN 163 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGK--DTVTKDNGIRP--- 283 +A + +SR EQDE+AL S A++A G D +VP + G+ +TV D P Sbjct: 164 IAERWNISREEQDEFALASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVV-DTDEHPRFG 222 Query: 284 SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYV 343 S++E +AKLKPAF K GTVTA N+S L D A+ ++IM+ EKA +G KP A + + Sbjct: 223 STIEGLAKLKPAF-KKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSA 281 Query: 344 SQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYM 403 DP + GP YAT +EKAG T++++D E +EAF+ Q LA K + D Sbjct: 282 GVDPA-IMGYGPFYATKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFD------- 333 Query: 404 GRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQ 463 + K N GG+++LGHP GA+G R+++ + ++K + GL C GGQ Sbjct: 334 ----------MNKVNVNGGAIALGHPIGASGARILVTLVHAMQKRDAKKGLATLCIGGGQ 383 Query: 464 GHAMIVE 470 G A+++E Sbjct: 384 GTAILLE 390 >6BN2-A nrPDB Length = 401 Score = 196 bits (497), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 139/426 (32%), Positives = 213/426 (50%), Gaps = 42/426 (9%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSV-PKEVVDYIIFGTVIQE 109 ++ V +V VRTP S + L A+ G L + ++ P E+ D + G V+Q Sbjct: 9 MKEVFIVSAVRTPMGSFMGSLSGVPATQLGAVAIKGALDKINLNPAEIQD-VYMGNVLQA 67 Query: 110 VKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 + A++AALGAG + TP V C S +A+ + +G + IVAGG+E MS Sbjct: 68 GEGQAPAKQAALGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDVEAIVAGGMENMS 127 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 VP H R G +L I K + L L ++ + + MG+ A+ Sbjct: 128 QVP--HYIDGRN-----------GVKLGDI-KLQDGLLKDGL---TDVYSKQHMGNCAEL 170 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKD----TVTKDNGIRPS 284 A + ++R EQD +A++S+ + KA EG +VVP +P + +D + Sbjct: 171 CAKEYNITREEQDAFAIQSYERSAKAWSEGKFKEEVVPVSIPQRKGEPIIFAEDEEYKNV 230 Query: 285 SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS 344 +++ L F K GTVTAAN+S L DGASA+++M++EK ++G KP A + + + Sbjct: 231 KFDRIPTLPTVFQKENGTVTAANASTLNDGASALVLMSKEKMESLGLKPLAKIVSYADAA 290 Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMG 404 Q P + P A P L KA LT+NDID FEF+EAFS LAN K + D Sbjct: 291 QAP-EWFTTAPAKALPIALAKANLTINDIDFFEFNEAFSVVGLANNKILGLD-------- 341 Query: 405 RKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQG 464 K N GG+++LGHP G++G R+++ N L++ +YG A C GG Sbjct: 342 ---------AAKVNVNGGAVALGHPLGSSGSRIIVTLINVLKQNNAKYGAAAICNGGGGA 392 Query: 465 HAMIVE 470 A+++E Sbjct: 393 SAIVIE 398 >6ARG-A nrPDB Length = 399 Score = 194 bits (493), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 144/426 (33%), Positives = 207/426 (48%), Gaps = 45/426 (10%) Query: 54 VVVVDGVRTP---FLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 V +V RTP FL S +S P A A L + V + FG VI Sbjct: 8 VYIVSSARTPVGSFLGSLSSLT--APQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISAN 65 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 N AR+ ALGAG + T TV C S +A+ G I +G DV+VAGG E MS+ Sbjct: 66 VGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSN 125 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 P + +L G + SL+ + L ++ E MG A+ Sbjct: 126 AP--------HYLPNLRTGAKYGHQ-SLVDGIMKDGL-------TDAGKQELMGLQAEEC 169 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPG-----KDTVTKDNGIRPS 284 A SR +QDEYA+R++ A+ AQ GL ++ P ++PG TVT+D + Sbjct: 170 AQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNL 229 Query: 285 SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS 344 + E++ +KPAFI GTVTA NSS L DGA+A+++++E K + KP A + + + Sbjct: 230 NPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAA 289 Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMG 404 Q P + P A PK L+ AG+ + IDAFE +EAFS LAN K + Sbjct: 290 QQP-SKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLL----------- 337 Query: 405 RKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQG 464 G+P EK N GG++++GHP GA+G R++ L+ + G+ G C GG Sbjct: 338 -----GIPE-EKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGA 391 Query: 465 HAMIVE 470 A++VE Sbjct: 392 SALVVE 397 >4E1L-A nrPDB Length = 395 Score = 193 bits (490), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 138/426 (32%), Positives = 217/426 (50%), Gaps = 43/426 (10%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 +++VV+V VRTP G +K+ L A+ + R + +D +I G V+Q Sbjct: 4 MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLNLSEIDEVIIGNVLQTG 63 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 NVAR+ A+ AG + P++TV C S +++ I SG+ DV++AGG E MS Sbjct: 64 LGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTENMSQ 123 Query: 171 VP-IRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 P I + + M ++ SM LI F MG +A+ Sbjct: 124 APYIVPTARFGSKMGNITMVDSMLTD-GLIDAF----------------NQYHMGITAEN 166 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKA-QDEGLLSDVVPFKV---PGK-DTVTKDNGIRPS 284 +A F +R QD+ AL S + A+ A ++ ++VP V GK +T+ KD + Sbjct: 167 IATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDEYPKLG 226 Query: 285 -SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYV 343 + E ++KLKPAF K GTVTA N+S + DGA+ +++M+++KA +G +P A ++ + Sbjct: 227 MTFEGLSKLKPAF-KKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASA 285 Query: 344 SQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYM 403 +P + + GP AT K L+KAGL++NDID E +EAF+ Q LA + D Sbjct: 286 GVEP-EVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQIDS------ 338 Query: 404 GRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQ 463 K N GG+++LGHP GA+G R+++ ++K + GL C GGQ Sbjct: 339 -----------SKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQ 387 Query: 464 GHAMIV 469 G +M+V Sbjct: 388 GISMVV 393 >2IBU-A nrPDB Length = 395 Score = 186 bits (471), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 139/430 (32%), Positives = 206/430 (47%), Gaps = 45/430 (10%) Query: 47 AKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTV 106 +KP ++ VV+V RTP S L L A+ G + + +PKE V G V Sbjct: 3 SKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNV 62 Query: 107 IQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 +Q + R+A LGAG TP T+ C S +A+ + G DV+VAGG+E Sbjct: 63 LQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 122 Query: 167 LMSDVPIRHSRKMRKLMLDLNKAKSMGQRLS-LISKFRFNFLAPELPAVSEFSTSETMGH 225 MS+VP +R G +L LI K +++ MG Sbjct: 123 SMSNVPYVMNR---------GSTPYGGVKLEDLIVK----------DGLTDVYNKIHMGS 163 Query: 226 SADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGK---DTVTK-DNG 280 A+ A ++R EQD YA+ S++ +K A + G ++V+P V K D V K D Sbjct: 164 CAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEE 223 Query: 281 IRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDF 340 + ++ KLK F K GTVTAAN+S L DGA+A+++M + A + P A + F Sbjct: 224 YKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAF 283 Query: 341 MYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAE 400 + +P D + P YA VL+ GL DI +E +EAFS +LAN K ++ D Sbjct: 284 ADAAVEPID-FPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDP--- 339 Query: 401 NYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAA 460 +K N GG++SLGHP G +G R+V + L++ G+YGL + C Sbjct: 340 --------------QKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASICNG 383 Query: 461 GGQGHAMIVE 470 GG AM+++ Sbjct: 384 GGGASAMLIQ 393 >1NL7-A nrPDB Length = 392 Score = 185 bits (470), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 139/426 (32%), Positives = 214/426 (50%), Gaps = 45/426 (10%) Query: 53 NVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKT 112 ++V+ RT ++ + H+L ++ +L R V V+ +I G V+ + Sbjct: 4 SIVIASAARTAVGSFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVLPAGEG 63 Query: 113 SNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVP 172 N AR+AA+ AG + A + C S +A+ G+ IA+G +IVAGG+E MS P Sbjct: 64 QNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESMSMAP 123 Query: 173 IRHSRKMRK--LMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 H +R M D +M + L F + + MG +A+ + Sbjct: 124 --HCAHLRGGVKMGDFKMIDTM-IKDGLTDAF-YGY---------------HMGTTAENV 164 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---TVTKDNGIR-PSS 285 A + +SR EQD +A+ S + A+ AQ +G D +VPF V G+ TV D IR ++ Sbjct: 165 AKQWQLSRDEQDAFAVASQNKAEAAQKDGRFKDEIVPFIVKGRKGDITVDADEYIRHGAT 224 Query: 286 LEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQ 345 L+ MAKL+PAF K GTVTA N+S L DGA+A L+M+E +A G +P + + V Sbjct: 225 LDSMAKLRPAFDKE-GTVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGV 283 Query: 346 DPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGR 405 DPK + GP A+ K LE+AG + D+D E +EAF+ Q A K + D Sbjct: 284 DPK-VMGTGPIPASRKALERAGWKIGDLDLVEANEAFAAQACAVNKDLGWD--------- 333 Query: 406 KTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGH 465 P + N GG++++GHP GA+G R++ +++ G + GL C GG G Sbjct: 334 ------PSIVNVN--GGAIAIGHPIGASGARILNTLLFEMKRRGARKGLATLCIGGGMGV 385 Query: 466 AMIVEA 471 AM +E+ Sbjct: 386 AMCIES 391 >2C7Y-A nrPDB Length = 404 Score = 178 bits (451), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 142/438 (32%), Positives = 211/438 (48%), Gaps = 71/438 (16%) Query: 53 NVVVVDGVRTPFLLSGT-SYKDLMPHDLARAALTGLLHRTSV-PKEVVDYIIFGTVIQE- 109 +VV+V RTP S ++KD P DL L L+ +T++ P EV D I+ GTV+ Sbjct: 14 DVVIVAAHRTPLCKSKRGNFKDTYPDDLLAPVLRALIEKTNLNPSEVGD-IVVGTVLAPG 72 Query: 110 VKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 + ++ R AA AGF + TV C S QA+ I +G D+ + G+E M+ Sbjct: 73 SQRASECRMAAFYAGFPETVAVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMT 132 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSET----MGH 225 P+ + PAV +F+ ++ MG Sbjct: 133 TNPMAWEGSVN-------------------------------PAVKKFAQAQNCLLPMGV 161 Query: 226 SADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---------TV 275 +++ +A F VSR EQD+ A+ SH A A G D ++P K D TV Sbjct: 162 TSENVAQRFGVSRQEQDQAAVDSHRKAAAATAAGKFKDEIIPVKTKLVDPKTGDEKPITV 221 Query: 276 TKDNGIRP-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPK 334 + D+GIRP ++L + KLKP F K GT TA NSS ++DGA A+L+M A+ G Sbjct: 222 SVDDGIRPTTTLASLGKLKPVF-KKDGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPVL 280 Query: 335 AYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMD 394 R F V DP + +GP A P ++ AGL ++DID FE +EAF+ Q Sbjct: 281 GVFRTFAAVGVDPA-IMGIGPAVAIPAAVKAAGLELDDIDLFEINEAFASQ--------- 330 Query: 395 SDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEG--GQY 452 ++ + K+GL P EK N GG++++GHP GATG R V + +++ G ++ Sbjct: 331 -------FVYCRNKLGLDP-EKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRF 382 Query: 453 GLVAACAAGGQGHAMIVE 470 G+V+ C G G A + E Sbjct: 383 GVVSMCIGTGMGAAAVFE 400 >5XYJ-B nrPDB Length = 408 Score = 174 bits (442), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 136/430 (31%), Positives = 211/430 (49%), Gaps = 47/430 (10%) Query: 52 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPK----EVVDYIIFGTVI 107 +NV +V RTP S +L AL G L + VP+ + D IIFG V+ Sbjct: 13 QNVYIVSTARTPIGSFQGSLSSKTAVELGAVALKGALAK--VPELDASKDFDEIIFGNVL 70 Query: 108 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167 AR+ AL AG S+ A TV SA +A+ G I G DV+VAGG E Sbjct: 71 SANLGQAPARQVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVAGGCES 130 Query: 168 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227 M++ P M GQ + L+ + L ++ MG A Sbjct: 131 MTNAPY--------YMPAARAGAKFGQTV-LVDGVERDGLNDAYDGLA-------MGVHA 174 Query: 228 DRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPG----KDT-VTKDNGI 281 ++ A + ++R +QD +A+ S+ ++K+Q EG +++VP + G DT VTKD Sbjct: 175 EKCARDWDITREQQDNFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEP 234 Query: 282 RPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFM 341 +E++ + F K GTVTAAN+S + DGA+A+++++E+ KP A ++ + Sbjct: 235 ARLHVEKLRSARTVFQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWG 294 Query: 342 YVSQDPKDQLLLGPTYATPKVLEKAGLT-MNDIDAFEFHEAFSGQILANFKAMDSDWFAE 400 + P D P+ A PK L+ AG+ +N +D FEF+EAFS L N K + D Sbjct: 295 EAAHQPAD-FTWAPSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLD---- 349 Query: 401 NYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAA 460 P K N +GG+++LGHP G +G R+V+ + L++EGG+ G+ A C Sbjct: 350 ------------P-SKVNVYGGAVALGHPLGCSGARVVVTLLSILQQEGGKIGVAAICNG 396 Query: 461 GGQGHAMIVE 470 GG ++++E Sbjct: 397 GGGASSIVIE 406 >2WUA-A nrPDB Length = 440 Score = 168 bits (425), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 131/433 (30%), Positives = 203/433 (46%), Gaps = 61/433 (14%) Query: 53 NVVVVDGVRTPFLLSGTS-YKDLMPHDLARAALTGLLHRTSV-PKEVVDYIIFGTVIQEV 110 +VV+V R+P + KD P D+ L L+ +T++ P EV D ++ + Sbjct: 34 DVVIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEVGDIVVGSVLGAGS 93 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 + ++ R AA AGF + P TV C S QA+ I +G D+ + G+E M+ Sbjct: 94 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTA 153 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 P+ + K K+M Q + LP MG +++ + Sbjct: 154 NPMAWEGSVNP------KVKTMAQAQDCL-----------LP----------MGITSENV 186 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---------TVTKDNG 280 A F+++R EQD+ A+ SH A G D ++P K D T++ D+G Sbjct: 187 AQKFSITRQEQDQAAVGSHRKTAAATAAGRFKDEIIPIKTKIVDPKTGDEKPVTISVDDG 246 Query: 281 IRP-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRD 339 IRP +SL +AKLKP F K G+ TA SS ++DGA A+L+M AL G R Sbjct: 247 IRPGTSLADLAKLKPVFRKD-GSTTAGTSSQVSDGAGAVLLMKRSIALQKGLPILGVFRT 305 Query: 340 FMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFA 399 F V P + +GP A P ++ AGL ++DID FE +EAF+ Q + K ++ D Sbjct: 306 FAAVGV-PPSIMGIGPAVAIPAAVKAAGLQIDDIDLFEINEAFASQFVYCQKKLEIDP-- 362 Query: 400 ENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEG--GQYGLVAA 457 +K N GG++++GHP GATG R V + +++ G ++G+V+ Sbjct: 363 ---------------QKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGRDCRFGVVSM 407 Query: 458 CAAGGQGHAMIVE 470 C G G A + E Sbjct: 408 CIGTGMGAAAVFE 420 >1WL4-A nrPDB Length = 397 Score = 166 bits (421), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 135/423 (31%), Positives = 205/423 (48%), Gaps = 41/423 (9%) Query: 54 VVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS 113 VV+V RT + + DL + +L R +V E V +IFG V+ Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67 Query: 114 NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPI 173 N R+A++GAG PA + M C S +A+ V I G ++VAGG+E MS P Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAP- 126 Query: 174 RHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAA 233 H +R +G+ + L + L F MG +A+ +A Sbjct: 127 -HLAYLRT-------GVKIGE-MPLTDSILCDGL------TDAFHNCH-MGITAENVAKK 170 Query: 234 FAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVP---GKDTVTKDNGIR-PSSLEQ 288 + VSR +QD+ A+ S + + AQ G ++VP V G V D R S++E Sbjct: 171 WQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEA 230 Query: 289 MAKLKPAFIKP-YGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDP 347 M+KLKP F+ GTVT AN+S + DGA+A+++M + +A G P A + + V +P Sbjct: 231 MSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEP 290 Query: 348 KDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKT 407 + +GP A + + KAG ++ D+D FE +EAF+ A K Sbjct: 291 S-IMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVK---------------- 333 Query: 408 KVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAM 467 ++GL P EK N GG+++LGHP GA+GCR+++ + L + G G+ A C GG G AM Sbjct: 334 ELGLNP-EKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAM 392 Query: 468 IVE 470 V+ Sbjct: 393 CVQ 395 >4WYS-A nrPDB Length = 405 Score = 166 bits (419), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 139/429 (32%), Positives = 203/429 (47%), Gaps = 47/429 (10%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 ++N V+V VRT S DL + + R + + VD +I G V+Q Sbjct: 4 MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAG 63 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 N AR+A L +G ++ TV C S +++ I +GQ IVAGG+E MS Sbjct: 64 LGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSL 123 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 P +LD KA+S G RL + + A + MG +A+ + Sbjct: 124 AP---------YLLDA-KARS-GYRLGDGQVYDVILRDGLMCATHGYH----MGITAENV 168 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVP--------GKDTVTKDNGI 281 A + ++R QDE AL S A A + G + ++VP V +D K N Sbjct: 169 AKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKAN-- 226 Query: 282 RPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFM 341 S+ E + L+PAF K GTVTA N+S + DGA+A++IM E ALA G P A ++ + Sbjct: 227 --STAEALGALRPAFDKA-GTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYA 283 Query: 342 YVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAEN 401 P + +GP AT K L+ AGL + DID E +EAF+ Q LA K + D Sbjct: 284 S-GGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDS---- 338 Query: 402 YMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAG 461 EK N GG+++LGHP GA+G R+++ + ++ GL C G Sbjct: 339 -------------EKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGG 385 Query: 462 GQGHAMIVE 470 GQG AM++E Sbjct: 386 GQGIAMVIE 394 >4O9A-A nrPDB Length = 398 Score = 162 bits (411), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 132/424 (31%), Positives = 206/424 (48%), Gaps = 41/424 (9%) Query: 53 NVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKT 112 +VV+V RT G S + +L + L R V E V +I G V+ Sbjct: 8 DVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAGSG 67 Query: 113 SNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVP 172 N AR+AA+ AG PA T+ S +A+ I +G +++VAGG E MS P Sbjct: 68 QNPARQAAIKAGLPAMVPAMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAAP 127 Query: 173 IRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAA 232 H + + AK L+ + L + MG +A+ +A Sbjct: 128 --HVLPGSRDGFRMGDAK-------LVDTMIVDGL-------WDVYNQYHMGITAENVAK 171 Query: 233 AFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGK--DTVT--KDNGIRP-SSL 286 + ++R QDE+A+ S + A+ AQ G ++VP +P + D V D +R ++L Sbjct: 172 EYGITREAQDEFAVGSQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATL 231 Query: 287 EQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQD 346 + M+ LKPAF K GTVTAAN+S L DGA+A+++M+ KA +G P A ++ + D Sbjct: 232 DSMSGLKPAFDK-AGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVD 290 Query: 347 PKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRK 406 PK + +GP A+ + L +A T D+D E +EAF+ Q LA + M D Sbjct: 291 PK-VMGMGPVPASKRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWD---------- 339 Query: 407 TKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHA 466 K N GG++++GHP GA+GCR+++ + +++ + GL + C GG G A Sbjct: 340 -------TSKVNVNGGAIAIGHPIGASGCRILVTLLHEMKRRDAKKGLASLCIGGGMGVA 392 Query: 467 MIVE 470 + VE Sbjct: 393 LAVE 396 >1PXT-A nrPDB Length = 390 Score = 158 bits (400), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 123/376 (32%), Positives = 174/376 (46%), Gaps = 57/376 (15%) Query: 105 TVIQEVKTSNVA---------REAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASG 155 +I+EV NV R A L +G TP + C S A+ I G Sbjct: 56 NLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVG 115 Query: 156 QCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVS 215 Q D+ +A GVE M+ N K++ L +IS + EL Sbjct: 116 QIDIGLALGVESMT-----------------NNYKNV-NPLGMIS-------SEELQKNR 150 Query: 216 EFSTSET-MGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD 273 E MG + + +AA F +SR +QDE+A S+ A KA++EGL D ++P K+P Sbjct: 151 EAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGS 210 Query: 274 TVTKDNGIRPS-SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYK 332 D G RP+ + E ++ ++PAFIK GT TA N+S ++DG + +L+ A + Sbjct: 211 ICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLP 270 Query: 333 PKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKA 392 DF V P + + +GP YA PKVLE GL + DID FE +EAF+ Q L Sbjct: 271 VLGRYIDFQTVGV-PPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHK 329 Query: 393 MDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQY 452 + D L K N GG+++LGHP G TG R V L+K+ Q Sbjct: 330 LGID-----------------LNKVNPRGGAIALGHPLGCTGARQVATILRELKKD--QI 370 Query: 453 GLVAACAAGGQGHAMI 468 G+V+ C G G A I Sbjct: 371 GVVSMCIGTGMGAAAI 386 >6BJB-A nrPDB Length = 393 Score = 155 bits (393), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 132/426 (30%), Positives = 199/426 (46%), Gaps = 47/426 (11%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 I +VV V RTP +++ ++ L R AL G L +V +V G V+ Sbjct: 7 ITDVVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVVVPSN 66 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 AR+ LGAG T V S +A+ ++ +++VAGG+E MS Sbjct: 67 AGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGMESMSC 126 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELP--AVSEFSTSETMGHSAD 228 VP R G+ F L +P +++ MG AD Sbjct: 127 VPFYLPR---------------GE-----IPFGGTKLIDGIPRDGLNDVYNDILMGACAD 166 Query: 229 RLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVP-GKDTVT--KDNGIRPS 284 ++A FA++R EQD+YA+ S+ + A EG+ + +++P +V GK T+T +D + Sbjct: 167 KVAKQFAITREEQDKYAILSYKRSAAAWKEGIFAKEIIPLEVTQGKKTITVEEDEEYKKV 226 Query: 285 SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS 344 + E++ KLKPAF G+VTAAN+S L DGA+ +++ + A G KP A + + + Sbjct: 227 NFEKIPKLKPAFTSE-GSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAA 285 Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMG 404 P D + P PKVL+ AGL + DID +E +EAF+ L K + D Sbjct: 286 THPID-FGIAPASVIPKVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDE------- 337 Query: 405 RKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQG 464 K N GG++SLGHP G +G R+V + L+ GQ G A C GG Sbjct: 338 ----------SKVNIHGGAVSLGHPIGMSGARIVGHLVHTLKP--GQKGCAAICNGGGGA 385 Query: 465 HAMIVE 470 MI+E Sbjct: 386 GGMIIE 391 >4UBW-A nrPDB Length = 399 Score = 151 bits (382), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 127/432 (29%), Positives = 199/432 (46%), Gaps = 63/432 (14%) Query: 55 VVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEV----VDYIIFGTVIQ-E 109 V+V+ R+P L +L A ++ + + + V+ +I G V Q Sbjct: 13 VIVEATRSPIGKRNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGCVTQFG 72 Query: 110 VKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 +++N++R A L AG + A TV C S QA GLIA+G DV +A G+E MS Sbjct: 73 EQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACGIEAMS 132 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 V + + G SLI ++ +LP ++F +A+R Sbjct: 133 RVGL---------------GANAGPDRSLIRAQSWDI---DLP--NQF-------EAAER 165 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVPGKDT----------VTKD 278 +A ++R + D + L S A++A EG ++ P + P D V +D Sbjct: 166 IAKRRGITREDVDVFGLESQRRAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRD 225 Query: 279 NGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLR 338 G+R +++ + +LKP G TA SS ++DGA+A+L M E A A G P+A + Sbjct: 226 QGLRETTMAGLGELKPVL--EGGIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIV 283 Query: 339 DFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWF 398 V +P L GP +T KVLEKAG+ + DID E +EAF+ +L+ W Sbjct: 284 AQALVGAEPYYHLD-GPVQSTAKVLEKAGMKIGDIDIVEINEAFASVVLS--------W- 333 Query: 399 AENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAAC 458 +V P +++ N GG+++LGHP G TG RL+ A + L + L+ C Sbjct: 334 --------ARVHEPDMDRVNVNGGAIALGHPVGCTGSRLITTALHELERTDQSLALITMC 385 Query: 459 AAGGQGHAMIVE 470 A G I+E Sbjct: 386 AGGALSTGTIIE 397 >3SVK-A nrPDB Length = 407 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 117/383 (30%), Positives = 174/383 (45%), Gaps = 69/383 (18%) Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 + ++AR A L AG + T + C S +A+ T + SG D+++AGGVE MS Sbjct: 69 QGGDIARTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSR 128 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 VP+ + N +R F+ P+ G AD + Sbjct: 129 VPMGSDGGAWATDPETN--------------YRIGFV-PQ-------------GIGADLI 160 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFK-VPGKDTVTKDNGIRP-SSLE 287 A SR + D YALRS A A G + VVP + G + D +RP +++E Sbjct: 161 ATLEGFSREDVDAYALRSQQKAAAAWSGGYFAKSVVPVRDQNGLVILDHDEHMRPDTTME 220 Query: 288 QMAKLKPAF-------------IKPYGTV-------TAANSSFLTDGASAMLIMAEEKAL 327 +AKLK AF ++ Y V T NSS + DGA+ +L+ +E+ Sbjct: 221 GLAKLKTAFDGVGEMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGK 280 Query: 328 AMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQIL 387 + G P+A + DP +L GPT AT KVL++AGLT++DID FE +EAF+ +L Sbjct: 281 SQGLTPRARIVATATSGSDPV-IMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASVVL 339 Query: 388 ANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRK 447 K ++ P EK N GG++++GHP GATG + + L + Sbjct: 340 KFQKDLNI-----------------PDEKLNVNGGAIAMGHPLGATGAMITGTMVDELER 382 Query: 448 EGGQYGLVAACAAGGQGHAMIVE 470 + L+ C GG G A I+E Sbjct: 383 RNARRALITLCIGGGMGVATIIE 405 >6BJA-A nrPDB Length = 397 Score = 137 bits (346), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 113/425 (26%), Positives = 196/425 (46%), Gaps = 44/425 (10%) Query: 52 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVK 111 ++V ++ VRTP ++ L DL + R+ +P ++ I G V+ Sbjct: 9 KDVYILSAVRTPIASFRSTLTSLSAVDLGIVVTKEAIKRSLLPSSAIEETIVGNVLSAGL 68 Query: 112 TSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDV 171 N+AR+ ++ + + T+ C S+ +A+ G I G ++VA G E MS+ Sbjct: 69 GQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSESMSNA 128 Query: 172 PIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLA 231 P R ++ + QR L+ + + MG A++ Sbjct: 129 PFYVPRG--EIPFGGVQLVDALQRDGLMDSIEY----------------QPMGLCAEKTV 170 Query: 232 AAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVPGKD----TVTKDNGIRPSSL 286 +A +R + D YA+ S+ A+ A EG + +VVP VP K +T+D + Sbjct: 171 KDYAFTREQLDAYAIESYRKAEHAWKEGAFNKEVVPVSVPQKRGSKVVLTEDEEYKRLIP 230 Query: 287 EQMAKLKPAFIKP-YGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQ 345 E++ L PAF+K GT+TAAN+S + DGA+A ++ + E KP A + + Sbjct: 231 EKVPALHPAFLKDGSGTITAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGV 290 Query: 346 DPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGR 405 +P D + P A ++L ++GL I +E +EAFS LA K + D Sbjct: 291 EPID-FTVAPALAVKQLLSQSGLDEESIALWEINEAFSVTGLAFIKELRLD--------- 340 Query: 406 KTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGH 465 P ++ N GG+++LGHP GA+G R+V+ + L+ + + G+ A C GG+ Sbjct: 341 -------P-KRVNVRGGAVALGHPLGASGARIVVTLVHALKSD--ELGVAAICNGGGEAS 390 Query: 466 AMIVE 470 A++++ Sbjct: 391 AILIK 395 >4B3J-C nrPDB Length = 403 Score = 131 bits (330), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 114/383 (29%), Positives = 172/383 (44%), Gaps = 69/383 (18%) Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 + ++AR A L +G + + C S +A+ T + SG D+++AGGVE MS Sbjct: 65 QGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSR 124 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 VP+ + +MG L + + F+ + AD + Sbjct: 125 VPMG------------SDGGAMG--LDPATNYDVMFVPQSI--------------GADLI 156 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFK-VPGKDTVTKDNGIRPSSL-E 287 A SR + D YALRS A +A G + VVP + G + D +RP + E Sbjct: 157 ATIEGFSREDVDAYALRSQQKAAEAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKE 216 Query: 288 QMAKLKPAF-------------IKPYGTV-------TAANSSFLTDGASAMLIMAEEKAL 327 +AKLKPAF ++ Y V T NSS + DGA+ ++I + Sbjct: 217 GLAKLKPAFEGLAALGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGK 276 Query: 328 AMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQIL 387 G P+A + DP +L GPT AT KVL++AGLT++DID FE +EAF+ +L Sbjct: 277 LQGLTPRARIVATATSGADPV-IMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVL 335 Query: 388 ANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRK 447 K ++ P EK N GG++++GHP GATG ++ + L + Sbjct: 336 KFQKDLNI-----------------PDEKLNVNGGAIAMGHPLGATGAMILGTMVDELER 378 Query: 448 EGGQYGLVAACAAGGQGHAMIVE 470 + L+ C GG G A I+E Sbjct: 379 RNARRALITLCIGGGMGVATIIE 401 >5LNQ-A nrPDB Length = 457 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 44/187 (23%), Positives = 78/187 (41%), Gaps = 16/187 (8%) Query: 282 RPSSLEQMAKLKPAFIKPYGTVT------AANSSFLTDGASAMLIMAEEKALAMGYKP-- 333 R + EQ P+ +K G T + S ++DG + +++ EE MG P Sbjct: 242 RKLTFEQCNGEDPSNVKFLGNETYKEYLRMTDCSQVSDGGAGVVLANEEGLRKMGLSPND 301 Query: 334 ------KAYLRDFMYVSQDPKDQL-LLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQI 386 K+ + +DP D + A K L A + +D++ E H+ F+ Sbjct: 302 SRLVEIKSIACAVSNLYEDPDDACCMFTSRQAAQKALSMANIKPSDLNVAEVHDCFTIAE 361 Query: 387 LANFKAMD-SDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRL 445 + ++A+ +++ + R L N GG LS GHP GATG + +M ++ Sbjct: 362 MLMYEALGIAEYGHAKDLIRNGDTTLEGRIPVNTGGGLLSFGHPVGATGIKQIMEVYRQM 421 Query: 446 RKEGGQY 452 + + Y Sbjct: 422 KGQCEAY 428 >4YZO-A nrPDB Length = 373 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 48/175 (27%), Positives = 77/175 (44%), Gaps = 21/175 (12%) Query: 311 LTDGASAMLIMAEEKALAMGYKPKAYLRDF------MYVSQDPKDQLLLGPTYATPKVLE 364 ++DGA+A++++ E AL+ KP Y++ YVS+ L A+ K + Sbjct: 199 ISDGAAAVVMVRNEDALSYTSKP-VYIKGIGSSNYTAYVSEKEDFVTLPAVVEASRKAFK 257 Query: 365 KAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEK---FNNWG 421 KA + ID E H+ IL ++ D F + + GL L+ N G Sbjct: 258 KA--KVERIDFAELHDM--ATILEIIQSEDIGLFKKGEGWKAVMEGLTSLDGEIPINPSG 313 Query: 422 GSLSLGHPFGATGCRLVMAAANRLRKEGG-------QYGLVAACAAGGQGHAMIV 469 G S GHP GA+G + A +++R E G + GL + A G +I+ Sbjct: 314 GLNSKGHPIGASGVAQAVEAFSQIRNEAGNRQVKNARVGLSLSMAGYGNSATVII 368 >4BI9-A nrPDB Length = 454 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 41/180 (22%), Positives = 78/180 (43%), Gaps = 17/180 (9%) Query: 288 QMAKLKPAFI-----KPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKP--------K 334 Q + P F+ KP+ + + S ++DG +A+++ +EE +G P K Sbjct: 248 QASDKNPNFLGNEIYKPF--LRTTDCSQVSDGGAAVILASEEGLQKLGLSPNDNRLVEIK 305 Query: 335 AYLRDFMYVSQDPKDQLLLGPTYATPKV-LEKAGLTMNDIDAFEFHEAFSGQILANFKAM 393 + + +D D + + + L AG+ + E H+ F+ L ++A+ Sbjct: 306 SLASAAGNLYEDSPDLTRMTTSMVAARTALSMAGVKPEQLQVAEVHDCFTIAELLMYEAL 365 Query: 394 D-SDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQY 452 +++ + R L N GG LS GHP GATG + V+ +++ + G+Y Sbjct: 366 GIAEYGGAGALIRSGATALDGRIPVNTGGGLLSFGHPVGATGVKQVLEVYRQMKGQCGEY 425 >6ESQ-A nrPDB Length = 392 Score = 41.6 bits (96), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 39/128 (30%), Positives = 61/128 (47%), Gaps = 17/128 (13%) Query: 51 IRNVVVVDGVRTPF-LLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGT---- 105 +R+V ++ +T F L S++DL+ +A + +V +D + G Sbjct: 1 MRDVAIIGYGQTKFGELWEDSFRDLIVEAGVKA-----IKDANVDGGDIDAMYIGNMSGG 55 Query: 106 --VIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAG 163 V QE S +A A L + P V AC S + A+ + V +ASG DV++AG Sbjct: 56 LFVGQEHIASLIADHAGL-----NPVPCTRVEAACASGSLALRSAVLSVASGHHDVVLAG 110 Query: 164 GVELMSDV 171 GVE M+DV Sbjct: 111 GVEKMTDV 118 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 46/179 (25%), Positives = 76/179 (42%), Gaps = 22/179 (12%) Query: 284 SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKA-YLRDFMY 342 ++LEQ+ P P +T + S ++DGASA+++ +KA K + Y++ Sbjct: 186 TTLEQVMNASP-VADP---LTLMHCSPVSDGASALIVCDADKAEEFAPKDEIIYIKASTQ 241 Query: 343 VS-----QDPKDQLLLGPT-YATPKVLEKAGLTMNDIDAFEFHEAFS--GQILANFKAMD 394 S D +D L A+ K + A + ID E H+ F+ G IL D Sbjct: 242 ASDTIALHDREDMTTLNAAKVASEKAYKLAKIAPEKIDVAEVHDCFAINGLILVE----D 297 Query: 395 SDWFAENYMGR-----KTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKE 448 + + G+ K ++ N GG + GH GATG R V +L+++ Sbjct: 298 LGFCKKGDAGKVIDEGKIRIDYDDFVTVNPSGGLKAAGHALGATGIRQVGELYWQLKQD 356 >6HRV-A nrPDB Length = 421 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 93/421 (22%), Positives = 152/421 (36%), Gaps = 75/421 (17%) Query: 51 IRNVVVVDGV-RTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQE 109 +RN V V GV T F G +D+ D+A+ A L + + G V + Sbjct: 12 LRNRVFVIGVGMTKFEKPGA--RDIDYPDMAKEAGQRALADAGIKYSAIQQACVGYVYGD 69 Query: 110 VKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 A +LG P V C + + A+ G LI G D ++A G E M Sbjct: 70 STCGQRAIYHSLGL---SGIPIINVNNNCSTGSTALFMGRQLIQGGLADCVLALGFEKME 126 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 R S + + ++ M + + ++ R+ A +PA + G++ Sbjct: 127 ----RGSLSSKYM----DRTNPMDKHMEVMIN-RYGLAA--VPAAPQM-----FGNAG-- 168 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQM 289 R ++Y + AK A S P+ + +D SLEQ+ Sbjct: 169 --------REHMEKYGTKPEHFAKVAWKNHKHSTNNPY------SQFQDE----YSLEQV 210 Query: 290 AKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAY-------LRDFMY 342 + K + +T +DGA A ++ +E G + KA + D Sbjct: 211 IDSR----KVFEFLTLLQCCPTSDGAGAAVLASESFVRRNGLEKKAVEIVAQEMVTDLST 266 Query: 343 VSQDPKDQLLLG---PTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMD----- 394 ++ ++G A + + AG+ +D+D E H+ FS L ++A+ Sbjct: 267 TFEENSCMKMVGYDMTRLAAERCYDTAGVKPSDVDVIELHDCFSANELITYEALGLCPEG 326 Query: 395 -----SDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEG 449 D Y G+ N GG +S GHP GATG +LR E Sbjct: 327 KAGELIDRGDNTYGGKWV---------INPSGGLISKGHPLGATGLAQCAELCWQLRAEA 377 Query: 450 G 450 G Sbjct: 378 G 378 >3KZU-A nrPDB Length = 428 Score = 37.4 bits (85), Expect = 0.016, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 7/81 (8%) Query: 86 GLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAM 145 G R P+ + + I G +I + + +V+ + L + P H+V AC + A+ Sbjct: 133 GYTLRDKGPRRISPFFIPGRLIN-LASGHVSIKHKL------RGPNHSVVTACATGTHAI 185 Query: 146 TTGVGLIASGQCDVIVAGGVE 166 LIA G DV+VAGG E Sbjct: 186 GDAARLIAFGDADVMVAGGTE 206 >6QSP-A nrPDB Length = 406 Score = 36.2 bits (82), Expect = 0.028, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 30/53 (56%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKL 182 PA T++ AC S+++A+ +G LI G D + GG + +S +PI + L Sbjct: 166 PAFTLSTACSSSSRAIISGQRLIEMGLVDAAIVGGADTLSRMPINGFDSLESL 218 >4U4E-A nrPDB Length = 383 Score = 35.0 bits (79), Expect = 0.075, Method: Compositional matrix adjust. Identities = 42/182 (23%), Positives = 76/182 (41%), Gaps = 20/182 (10%) Query: 283 PSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYL----- 337 P ++E + +P + P+ + + +TD A ++ + E+A + P A L Sbjct: 183 PITIEDVLNSRP-IVWPFNLL---DCCLVTDAGGACVVTSIERARDLRQHPVAILGVGES 238 Query: 338 RDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDW 397 D +SQ P + + AG+T +DID +++F+ +L + + + Sbjct: 239 HDHSIISQMPS-LTSFAARRSGQAAFKMAGVTHDDIDLAMIYDSFTYTVLLSLEDLGFCA 297 Query: 398 FAEN---YMGRKTKVG--LPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQY 452 E G++T G P N GG LS HP G G ++ A +LR + Sbjct: 298 KGEGGAFVSGQRTAPGGDFP----MNTNGGGLSYTHP-GMYGMFAIIEAVRQLRHDYADQ 352 Query: 453 GL 454 G+ Sbjct: 353 GI 354 >5M3K-C nrPDB Length = 398 Score = 34.7 bits (78), Expect = 0.084, Method: Compositional matrix adjust. Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 12/124 (9%) Query: 52 RNVVVVDGVRTPFLLSG---TSYKDLMPHDLARAALTGLLHRTSVPKEV--VDYIIFGTV 106 R V +V TP S ++K+++ +A +H P+E+ V Y G Sbjct: 4 RRVAIVSAAYTPKPGSSRVRQTFKEMIVESAYKALKDAKMH----PREIQAVAYGYHGEG 59 Query: 107 IQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 I E ALG P T C S++ + G ++ASG+ D+++ GG E Sbjct: 60 ISEYGGLGPTISDALGI---SPAPTFMSTANCTSSSVSFQMGHQMVASGEYDIVLCGGFE 116 Query: 167 LMSD 170 M+D Sbjct: 117 KMTD 120 >3E60-A nrPDB Length = 424 Score = 34.7 bits (78), Expect = 0.084, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 22/39 (56%) Query: 128 KTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 + P H+V AC + A+ LIA G DV++AGG E Sbjct: 164 RGPNHSVVTACSTGAHAIGDAARLIALGDADVMLAGGTE 202 >2IWZ-A nrPDB Length = 438 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 21/39 (53%) Query: 128 KTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 K P H V+ AC + A+ IA G DV+VAGG + Sbjct: 178 KGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTD 216 >4JPF-A nrPDB Length = 436 Score = 33.1 bits (74), Expect = 0.30, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 94 PKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIA 153 P+ + + + G++I V L + P + +T AC + ++ IA Sbjct: 149 PRRISPFFVPGSIINMVS-------GFLSIHLGLQGPNYALTTACTTGTHSIGMAARNIA 201 Query: 154 SGQCDVIVAGGVEL 167 G+ DV+VAGG E+ Sbjct: 202 YGEADVMVAGGSEM 215 >1J3N-A nrPDB Length = 408 Score = 32.3 bits (72), Expect = 0.41, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 23/37 (62%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 P+ TV AC + A+ + + +I G+ D+++AGG E Sbjct: 153 PSSTVVTACATGADALGSALRMIQLGEADLVLAGGTE 189 >3PND-A nrPDB Length = 337 Score = 31.6 bits (70), Expect = 0.84, Method: Compositional matrix adjust. Identities = 32/135 (23%), Positives = 57/135 (42%), Gaps = 6/135 (4%) Query: 149 VGLIASGQCDVIVAGGVELMSDVPIRHSRKM-RKLMLDLNKAKSMGQRLSLISKFRFNFL 207 +G G D+ V V L P R + +D KAK+ Q L +I + FL Sbjct: 93 IGAKTDGAMDITVGPLVNLWGFGPDRQPLHIPTPAQIDAAKAKTGLQHLQVIDRAGHQFL 152 Query: 208 APELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPF 267 +LP + ++ G++AD LA +EQ+ A S+ G+ + P+ Sbjct: 153 QKDLPDLYVDLSTVGEGYAADHLA-----RLMEQEGIARYLVSVGGALSSRGMNAQGQPW 207 Query: 268 KVPGKDTVTKDNGIR 282 +V + ++N ++ Sbjct: 208 RVAIQKPTDRENAVQ 222 >4XGV-A nrPDB Length = 340 Score = 31.2 bits (69), Expect = 0.97, Method: Compositional matrix adjust. Identities = 30/135 (22%), Positives = 62/135 (45%), Gaps = 6/135 (4%) Query: 149 VGLIASGQCDVIVAGGVELMSDVPIRHSRKM-RKLMLDLNKAKSMGQRLSLISKFRFNFL 207 +G G D+ V V L P + ++ + +D KAK+ Q L++I++ +L Sbjct: 94 IGAKTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQHLTVINQSHQQYL 153 Query: 208 APELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPF 267 +LP + ++ G++AD LA +EQ+ + S+ G+ + +P+ Sbjct: 154 QKDLPDLYVDLSTVGEGYAADHLARL-----MEQEGISRYLVSVGGALNSRGMNGEGLPW 208 Query: 268 KVPGKDTVTKDNGIR 282 +V + K+N ++ Sbjct: 209 RVAIQKPTDKENAVQ 223 >4JGA-A nrPDB Length = 437 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 124 GFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 GFS P T AC + A+ + +I G DV++AGG E Sbjct: 173 GFS--GPNQTAVTACSTGAHAIGDAMRMIKHGYADVMIAGGAE 213 >6ET0-A nrPDB Length = 365 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 13/23 (56%), Positives = 16/23 (69%) Query: 358 ATPKVLEKAGLTMNDIDAFEFHE 380 A + LEKAGL +DID F FH+ Sbjct: 265 AMRRALEKAGLGSDDIDYFVFHQ 287 >3VWB-A nrPDB Length = 143 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 2/42 (4%) Query: 59 GVRTPFL-LSGTSYKDLMP-HDLARAALTGLLHRTSVPKEVV 98 G+ FL +SG SYKD+ +L+RA +T SVP+E++ Sbjct: 31 GIGLNFLKVSGMSYKDIAKKENLSRAKVTRAFQAASVPQEII 72 >4QAV-A nrPDB Length = 415 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 128 KTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 + P++ + AC + A+ LI G D++VAGG E Sbjct: 155 RGPSYGMVSACTTGAHAIGNSARLIKYGDADIMVAGGAE 193 >2IX4-A nrPDB Length = 431 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 P H AC + ++ +I G DV+VAGG E Sbjct: 171 PNHAAVTACATGAHSIGDATRMIQFGDADVMVAGGTE 207 >4DDO-A nrPDB Length = 451 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 24/43 (55%) Query: 128 KTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 + P AC ++ QA+ + +I +G+ DV++AGG E D Sbjct: 183 RGPLGCPVTACAASVQAIGDAMRMIRTGEADVVLAGGAEAAFD 225 >3LGS-A nrPDB Length = 267 Score = 29.3 bits (64), Expect = 3.9, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 12/94 (12%) Query: 100 YIIFGTVIQEVKTSNVA--REAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQC 157 ++++ V ++++ + V R+AALG PA +T A I QA+ + +I +G C Sbjct: 62 WVLYHGVHKDLRINVVCPGRDAALGIDSVGTVPASLITFASI---QALKPDI-IINAGTC 117 Query: 158 DVIVA-----GGVELMSDVPIRHSRKMRKLMLDL 186 G V L+SDV + H R++ M DL Sbjct: 118 GGFKVKGANIGDVFLVSDV-VFHDRRIPIPMFDL 150 >3HHE-A nrPDB Length = 255 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 11/116 (9%) Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSAD-- 228 VPI K+ +L LD++ A +G ++LI L ++ A S S M AD Sbjct: 88 VPISTLEKIPELDLDIDGADEIGPEMTLIKGGGGALLHEKIVA----SASRAMFVIADET 143 Query: 229 ---RLAAAFAVSRLEQDEYALRSHSLA-KKAQDEGLLSDVVPFKVPGKDTVTKDNG 280 + AFA+ +E + + + + +A +KA D LS + ++ G D D G Sbjct: 144 KMVKTLGAFALP-IEVNPFGIHATRIAIEKAADNLGLSGEITLRMNGDDPFKTDGG 198 >2GP6-A nrPDB Length = 434 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 119 AALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL-MSDVPIRHSR 177 AA+G K T AC S +A+ I G+ D + GGVE + VPI Sbjct: 168 AAVGLERHAKAGVMTPVSACASGAEAIARAWQQIVLGEADAAICGGVETRIEAVPIAGFA 227 Query: 178 KMRKLM 183 +MR +M Sbjct: 228 QMRIVM 233 >1JPU-A nrPDB Length = 370 Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Query: 84 LTGLLHRTSVPKEVVDYIIFG-TVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISAN 142 L G+ ++T V + + + I G T++ E+K N+A E + +G + + + A Sbjct: 27 LEGIGNKTVVIADEIVWKIAGHTIVNELKKGNIAAEEVVFSGEASRNEVERIANIARKAE 86 Query: 143 QAMTTGVG 150 A+ GVG Sbjct: 87 AAIVIGVG 94 >5BQS-A nrPDB Length = 323 Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust. Identities = 43/151 (28%), Positives = 64/151 (42%), Gaps = 11/151 (7%) Query: 78 DLARAALTGLLHRTSVPKEVVDYIIFGTVI-QEVKTSNVAR-EAALGAGFSDKTPAHTVT 135 DLA L+ + + + +D+II T+ + S AR +A +GA +K A +T Sbjct: 52 DLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGA---NKAFAFDLT 108 Query: 136 MACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQR 195 AC A++T IASG+ + G E +S R L D G Sbjct: 109 AACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGD-----GAGGV 163 Query: 196 LSLISKFRFNFLAPELPAVSEFSTSETMGHS 226 L L + + +FLA L + S T GHS Sbjct: 164 L-LEASEQEHFLAESLNSDGSRSECLTYGHS 193 >3IL7-A nrPDB Length = 313 Score = 28.9 bits (63), Expect = 5.6, Method: Compositional matrix adjust. Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 7/38 (18%) Query: 358 ATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDS 395 A+ +V+EKA LT +DID F H+ AN + M+S Sbjct: 217 ASTRVVEKANLTSDDIDLFIPHQ-------ANIRIMES 247 >1QN4-A nrPDB Length = 200 Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 26/57 (45%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 107 I+N+V V+ P L G +Y GL++R VPK V+ + G ++ Sbjct: 115 IQNIVGSCDVKFPIRLEGLAYSHAAFSSYEPELFPGLIYRMKVPKIVLLIFVSGKIV 171 >4EWP-A nrPDB Length = 350 Score = 28.1 bits (61), Expect = 9.6, Method: Compositional matrix adjust. Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 1/98 (1%) Query: 88 LHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTT 147 L R + +D +I TV T + A A G + PA+ V+ AC + Sbjct: 74 LERAGLQGSDLDAVIVSTVTFPHATPSAAALVAHEIGAT-PAPAYDVSAACAGYCYGVAQ 132 Query: 148 GVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLD 185 L+ SG ++ GVE +SDV R + L+ D Sbjct: 133 ADALVRSGTARHVLVVGVERLSDVVDPTDRSISFLLGD 170 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5ZQZ-B nrPDB 629 0.0 4N44-A nrPDB 481 e-136 4E1L-A nrPDB 467 e-132 4DD5-A nrPDB 461 e-130 3SS6-A nrPDB 451 e-127 1ULQ-A nrPDB 445 e-125 6BN2-A nrPDB 443 e-125 2IBU-A nrPDB 442 e-124 1NL7-A nrPDB 441 e-124 1WL4-A nrPDB 439 e-123 4NZS-A nrPDB 433 e-122 4O9A-A nrPDB 431 e-121 4C2K-A nrPDB 431 e-121 4WYS-A nrPDB 426 e-120 6ARG-A nrPDB 424 e-119 3GOA-A nrPDB 423 e-118 5LP7-H nrPDB 420 e-118 1WDK-C nrPDB 420 e-118 2IIK-A nrPDB 416 e-116 5CBQ-A nrPDB 416 e-116 5XYJ-B nrPDB 411 e-115 6BJB-A nrPDB 404 e-113 6BJA-A nrPDB 401 e-112 2C7Y-A nrPDB 397 e-111 2WUA-A nrPDB 392 e-109 1PXT-A nrPDB 381 e-106 4UBW-A nrPDB 366 e-101 3SVK-A nrPDB 361 e-100 4B3J-C nrPDB 354 7e-98 6HRV-A nrPDB 275 2e-74 5LNQ-A nrPDB 206 1e-53 6ESQ-A nrPDB 189 3e-48 4BI9-A nrPDB 173 2e-43 4YZO-A nrPDB 160 1e-39 Sequences not found previously or not previously below threshold: 5M3K-C nrPDB 100 9e-22 4U4E-A nrPDB 84 9e-17 4EWP-A nrPDB 54 2e-07 5AB6-A nrPDB 53 2e-07 4X0O-A nrPDB 52 7e-07 5BY7-A nrPDB 49 4e-06 4DFE-A nrPDB 49 5e-06 4YUC-A nrPDB 49 6e-06 1J3N-A nrPDB 49 7e-06 3O04-A nrPDB 47 1e-05 3IL7-A nrPDB 47 2e-05 4QAV-A nrPDB 47 2e-05 3E60-A nrPDB 47 2e-05 3KZU-A nrPDB 46 3e-05 6QSP-A nrPDB 46 3e-05 4V2P-A nrPDB 46 4e-05 4NHD-A nrPDB 46 4e-05 3H76-A nrPDB 46 5e-05 5W2O-A nrPDB 45 6e-05 2EBD-A nrPDB 45 7e-05 3GWE-A nrPDB 44 1e-04 2IX4-A nrPDB 44 1e-04 2GP6-A nrPDB 44 1e-04 1OXH-A nrPDB 44 2e-04 1MZJ-A nrPDB 44 2e-04 4RYB-A nrPDB 43 3e-04 4JPF-A nrPDB 43 3e-04 4DDO-A nrPDB 43 4e-04 5BQS-A nrPDB 42 5e-04 4R8E-A nrPDB 42 7e-04 4JRH-A nrPDB 42 7e-04 4JGA-A nrPDB 41 0.002 5ENY-A nrPDB 40 0.002 3IL4-A nrPDB 40 0.002 4LS7-A nrPDB 40 0.002 2AJ9-A nrPDB 40 0.003 2IWZ-A nrPDB 39 0.004 5YO9-A nrPDB 39 0.005 6ESQ-I nrPDB 38 0.009 3HO9-A nrPDB 38 0.009 4EFI-A nrPDB 37 0.014 4OQJ-A nrPDB 37 0.025 4JD3-A nrPDB 36 0.037 4XOX-A nrPDB 36 0.044 1PV9-A nrPDB 35 0.066 4YLT-A nrPDB 35 0.067 1WY2-A nrPDB 35 0.088 5BNS-A nrPDB 34 0.12 2BZ4-A nrPDB 34 0.13 2P1R-A nrPDB 34 0.13 1TQY-B nrPDB 34 0.14 1TQY-A nrPDB 34 0.16 3OA3-A nrPDB 34 0.16 1UB7-A nrPDB 34 0.17 1E5M-A nrPDB 34 0.22 6ET0-A nrPDB 33 0.28 2GQD-A nrPDB 32 0.52 2OEL-A nrPDB 32 0.68 3OYT-A nrPDB 32 0.74 4COG-A nrPDB 31 1.0 3VEW-A nrPDB 31 1.1 5N6R-A nrPDB 31 1.2 5MB9-A nrPDB 31 1.2 4KJD-A nrPDB 30 1.6 5LBT-A nrPDB 30 1.8 4HA6-A nrPDB 30 3.2 3U0E-A nrPDB 29 4.1 2IVO-A nrPDB 29 5.4 5X41-A nrPDB 28 9.5 >5ZQZ-B nrPDB Length = 474 Score = 629 bits (1622), Expect = 0.0, Method: Composition-based stats. Identities = 474/474 (100%), Positives = 474/474 (100%) Query: 1 MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGV 60 MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGV Sbjct: 1 MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGV 60 Query: 61 RTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAA 120 RTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAA Sbjct: 61 RTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAA 120 Query: 121 LGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMR 180 LGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMR Sbjct: 121 LGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMR 180 Query: 181 KLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLE 240 KLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLE Sbjct: 181 KLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLE 240 Query: 241 QDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPY 300 QDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPY Sbjct: 241 QDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPY 300 Query: 301 GTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATP 360 GTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATP Sbjct: 301 GTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATP 360 Query: 361 KVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNW 420 KVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNW Sbjct: 361 KVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNW 420 Query: 421 GGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK 474 GGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK Sbjct: 421 GGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK 474 >4N44-A nrPDB Length = 400 Score = 481 bits (1238), Expect = e-136, Method: Composition-based stats. Identities = 143/425 (33%), Positives = 215/425 (50%), Gaps = 40/425 (9%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 ++ VV+ VRT G S KD+ DL A+ + + + E V+ +I G V+Q Sbjct: 1 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAG 60 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 N AR+A+ AG + PA T+ C S + ++ +I +G DVI+AGG+E MS Sbjct: 61 LGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSR 120 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 P L G R+ +KF + L + MG +A+ + Sbjct: 121 APY------------LANNARWGYRMGN-AKFVDEMITDGL---WDAFNDYHMGITAENI 164 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---TVTKDNGIR-PSS 285 A + +SR EQDE+AL S A++A G D +VP + G+ V D R S+ Sbjct: 165 AERWNISREEQDEFALASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGST 224 Query: 286 LEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQ 345 +E +AKLKPAF K GTVTA N+S L D A+ ++IM+ EKA +G KP A + + Sbjct: 225 IEGLAKLKPAF-KKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGV 283 Query: 346 DPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGR 405 DP + GP YAT +EKAG T++++D E +EAF+ Q LA K + D Sbjct: 284 DPA-IMGYGPFYATKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFD--------- 333 Query: 406 KTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGH 465 + K N GG+++LGHP GA+G R+++ + ++K + GL C GGQG Sbjct: 334 --------MNKVNVNGGAIALGHPIGASGARILVTLVHAMQKRDAKKGLATLCIGGGQGT 385 Query: 466 AMIVE 470 A+++E Sbjct: 386 AILLE 390 >4E1L-A nrPDB Length = 395 Score = 467 bits (1201), Expect = e-132, Method: Composition-based stats. Identities = 131/425 (30%), Positives = 210/425 (49%), Gaps = 41/425 (9%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 +++VV+V VRTP G +K+ L A+ + R + +D +I G V+Q Sbjct: 4 MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLNLSEIDEVIIGNVLQTG 63 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 NVAR+ A+ AG + P++TV C S +++ I SG+ DV++AGG E MS Sbjct: 64 LGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTENMSQ 123 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 P G ++ I+ + + MG +A+ + Sbjct: 124 APYIVP------------TARFGSKMGNITMVDSMLT----DGLIDAFNQYHMGITAENI 167 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGK----DTVTKDNGIR-PS 284 A F +R QD+ AL S + A+ A ++VP V + +T+ KD + Sbjct: 168 ATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDEYPKLGM 227 Query: 285 SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS 344 + E ++KLKPAF K GTVTA N+S + DGA+ +++M+++KA +G +P A ++ + Sbjct: 228 TFEGLSKLKPAF-KKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAG 286 Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMG 404 +P + + GP AT K L+KAGL++NDID E +EAF+ Q LA + D Sbjct: 287 VEP-EVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQIDS------- 338 Query: 405 RKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQG 464 K N GG+++LGHP GA+G R+++ ++K + GL C GGQG Sbjct: 339 ----------SKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQG 388 Query: 465 HAMIV 469 +M+V Sbjct: 389 ISMVV 393 >4DD5-A nrPDB Length = 396 Score = 461 bits (1187), Expect = e-130, Method: Composition-based stats. Identities = 135/426 (31%), Positives = 220/426 (51%), Gaps = 40/426 (9%) Query: 50 NIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQE 109 N+R VV+ RT G ++K + +L A + R ++ +++D + G V+ Sbjct: 5 NMREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANITPDMIDESLLGGVLTA 64 Query: 110 VKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 N+AR+ ALGAG + PA T+ + C S ++++ LIA G D+++ GG E MS Sbjct: 65 GLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGAENMS 124 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 P L+ MG + S + +S+ + MG +A+ Sbjct: 125 MSPY--------LVPSARYGARMGDAAFVDSMIK--------DGLSDIFNNYHMGITAEN 168 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKD---TVTKDNGIRP-S 284 +A + ++R EQDE AL S + A+KAQ EG ++VP + G+ V KD I+P + Sbjct: 169 IAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEYIKPGT 228 Query: 285 SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS 344 ++E++AKL+PAF K GTVTA N+S + DGA+ +++MA+EKA +G +P A + + Sbjct: 229 TMEKLAKLRPAF-KKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAG 287 Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMG 404 DPK + GP AT K LE A +T+ DID E +EAF+ Q +A + ++ D Sbjct: 288 VDPK-IMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNID-------- 338 Query: 405 RKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQG 464 + K N GG++++GHP G +G R++ +++ + GL C GG G Sbjct: 339 ---------MNKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMG 389 Query: 465 HAMIVE 470 +IV+ Sbjct: 390 TTLIVK 395 >3SS6-A nrPDB Length = 394 Score = 451 bits (1161), Expect = e-127, Method: Composition-based stats. Identities = 147/428 (34%), Positives = 211/428 (49%), Gaps = 45/428 (10%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 + NVV+ VR+P G + K++ P +LA L + R V VD +I G IQ Sbjct: 4 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRT 63 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 +N AR AAL AGF D +T+ C S QA+ + I G +V+VAGGVE MS Sbjct: 64 DEANTARTAALAAGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGVEAMSS 123 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRL--SLISKFRFNFLAPELPAVSEFSTSETMGHSAD 228 P + GQRL I + L + + MG +A+ Sbjct: 124 SPYALKQH------------RWGQRLQHGEIRDTVWEVLEDPIHHI-------MMGETAE 164 Query: 229 RLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---TVTKDNGIR-P 283 L + ++R EQDE ALRSH+LA KA + G D +VP + + +KD R Sbjct: 165 NLVEQYEITREEQDEVALRSHTLALKAIESGYFDDQIVPITIKERRKEVVFSKDEHPRAD 224 Query: 284 SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYV 343 + E++A LKPAF K G+VTA N+S L DG++ +++M+EEKA G +P A + + Sbjct: 225 ITAEKLAGLKPAFRKD-GSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVA 283 Query: 344 SQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYM 403 DPK + +GP A K LEK ++ D D E +EAF+ Q LA K +D D Sbjct: 284 GVDPK-IMGIGPAPAIRKGLEKVDWSLEDADLLEINEAFAAQYLAVEKELDLD------- 335 Query: 404 GRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQ 463 EK N G + LGHP G TG R+ ++ + L++ G + G+ + C GG Sbjct: 336 ----------REKVNVNGSGVGLGHPIGCTGARITVSLIHELKRRGLEKGIASLCVGGGI 385 Query: 464 GHAMIVEA 471 G A+ +EA Sbjct: 386 GVALFIEA 393 >1ULQ-A nrPDB Length = 401 Score = 445 bits (1145), Expect = e-125, Method: Composition-based stats. Identities = 142/426 (33%), Positives = 216/426 (50%), Gaps = 34/426 (7%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 + +V+ VRTP G + + P DL AL+ L+ R+ VPKE V+ + G Q Sbjct: 1 MPEAWIVEAVRTPIGKHGGALASVRPDDLLAHALSVLVDRSGVPKEEVEDVYAGCANQAG 60 Query: 111 KTS-NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 + + NVAR A L AGF + TV C S +A+ I +G+ V + GVE MS Sbjct: 61 EDNRNVARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVESMS 120 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 P + R G + + + F+ P++ A+ +E+MG +A+ Sbjct: 121 RAPYAVPKPERGF--------PTGNLVMYDTTLGWRFVNPKMQAL---YGTESMGETAEN 169 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKDT---VTKDNGIRP-S 284 LA + + R EQD +AL SH A +A +EG +VVP V V +D G R + Sbjct: 170 LAEMYGIRREEQDRFALLSHQKAVRAWEEGRFQDEVVPVPVKRGKEEILVEQDEGPRRDT 229 Query: 285 SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS 344 SLE++A L+P F + GTVTA NSS L DGA+A+L+++++ A A G +P A +R Sbjct: 230 SLEKLAALRPVF-REGGTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAG 288 Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMG 404 P + +GP AT K LE+AGL+ +D+ E +EAF+ Q LA + Sbjct: 289 V-PPRIMGIGPVPATRKALERAGLSFSDLGLIELNEAFAAQALAVLREWSLSMED----- 342 Query: 405 RKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQG 464 ++ N GG+++LGHP GA+G R++ + +R+ Q+GL C GQG Sbjct: 343 ----------QRLNPNGGAIALGHPLGASGARILTTLVHEMRRRKVQFGLATMCIGVGQG 392 Query: 465 HAMIVE 470 A++VE Sbjct: 393 IAVVVE 398 >6BN2-A nrPDB Length = 401 Score = 443 bits (1140), Expect = e-125, Method: Composition-based stats. Identities = 133/425 (31%), Positives = 208/425 (48%), Gaps = 40/425 (9%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 ++ V +V VRTP S + L A+ G L + ++ + + G V+Q Sbjct: 9 MKEVFIVSAVRTPMGSFMGSLSGVPATQLGAVAIKGALDKINLNPAEIQDVYMGNVLQAG 68 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 + A++AALGAG + TP V C S +A+ + +G + IVAGG+E MS Sbjct: 69 EGQAPAKQAALGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDVEAIVAGGMENMSQ 128 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 VP +D +G K + L L ++ + + MG+ A+ Sbjct: 129 VPHY---------IDGRNGVKLG-----DIKLQDGLLKDGL---TDVYSKQHMGNCAELC 171 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKD----TVTKDNGIRPSS 285 A + ++R EQD +A++S+ + KA EG +VVP +P + +D + Sbjct: 172 AKEYNITREEQDAFAIQSYERSAKAWSEGKFKEEVVPVSIPQRKGEPIIFAEDEEYKNVK 231 Query: 286 LEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQ 345 +++ L F K GTVTAAN+S L DGASA+++M++EK ++G KP A + + +Q Sbjct: 232 FDRIPTLPTVFQKENGTVTAANASTLNDGASALVLMSKEKMESLGLKPLAKIVSYADAAQ 291 Query: 346 DPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGR 405 P + P A P L KA LT+NDID FEF+EAFS LAN K + D Sbjct: 292 AP-EWFTTAPAKALPIALAKANLTINDIDFFEFNEAFSVVGLANNKILGLD--------- 341 Query: 406 KTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGH 465 K N GG+++LGHP G++G R+++ N L++ +YG A C GG Sbjct: 342 --------AAKVNVNGGAVALGHPLGSSGSRIIVTLINVLKQNNAKYGAAAICNGGGGAS 393 Query: 466 AMIVE 470 A+++E Sbjct: 394 AIVIE 398 >2IBU-A nrPDB Length = 395 Score = 442 bits (1136), Expect = e-124, Method: Composition-based stats. Identities = 134/429 (31%), Positives = 203/429 (47%), Gaps = 43/429 (10%) Query: 47 AKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTV 106 +KP ++ VV+V RTP S L L A+ G + + +PKE V G V Sbjct: 3 SKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNV 62 Query: 107 IQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 +Q + R+A LGAG TP T+ C S +A+ + G DV+VAGG+E Sbjct: 63 LQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 122 Query: 167 LMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHS 226 MS+VP +R G +L + +++ MG Sbjct: 123 SMSNVPYVMNRGSTPYG---------GVKLEDLIVK---------DGLTDVYNKIHMGSC 164 Query: 227 ADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGK----DTVTKDNGI 281 A+ A ++R EQD YA+ S++ +K A + G ++V+P V K V +D Sbjct: 165 AENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEY 224 Query: 282 RPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFM 341 + ++ KLK F K GTVTAAN+S L DGA+A+++M + A + P A + F Sbjct: 225 KRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFA 284 Query: 342 YVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAEN 401 + +P D + P YA VL+ GL DI +E +EAFS +LAN K ++ D Sbjct: 285 DAAVEPID-FPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDP---- 339 Query: 402 YMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAG 461 +K N GG++SLGHP G +G R+V + L++ G+YGL + C G Sbjct: 340 -------------QKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASICNGG 384 Query: 462 GQGHAMIVE 470 G AM+++ Sbjct: 385 GGASAMLIQ 393 >1NL7-A nrPDB Length = 392 Score = 441 bits (1134), Expect = e-124, Method: Composition-based stats. Identities = 134/423 (31%), Positives = 208/423 (49%), Gaps = 41/423 (9%) Query: 54 VVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS 113 +V+ RT ++ + H+L ++ +L R V V+ +I G V+ + Sbjct: 5 IVIASAARTAVGSFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVLPAGEGQ 64 Query: 114 NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPI 173 N AR+AA+ AG + A + C S +A+ G+ IA+G +IVAGG+E MS P Sbjct: 65 NPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESMSMAPH 124 Query: 174 RHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAA 233 + M D +M + +++ MG +A+ +A Sbjct: 125 CAHLRGGVKMGDFKMIDTMIK-----------------DGLTDAFYGYHMGTTAENVAKQ 167 Query: 234 FAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---TVTKDNGIR-PSSLEQ 288 + +SR EQD +A+ S + A+ AQ +G D +VPF V G+ TV D IR ++L+ Sbjct: 168 WQLSRDEQDAFAVASQNKAEAAQKDGRFKDEIVPFIVKGRKGDITVDADEYIRHGATLDS 227 Query: 289 MAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPK 348 MAKL+PAF K GTVTA N+S L DGA+A L+M+E +A G +P + + V DPK Sbjct: 228 MAKLRPAFDKE-GTVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPK 286 Query: 349 DQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTK 408 + GP A+ K LE+AG + D+D E +EAF+ Q A K + D Sbjct: 287 -VMGTGPIPASRKALERAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSI--------- 336 Query: 409 VGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMI 468 N GG++++GHP GA+G R++ +++ G + GL C GG G AM Sbjct: 337 --------VNVNGGAIAIGHPIGASGARILNTLLFEMKRRGARKGLATLCIGGGMGVAMC 388 Query: 469 VEA 471 +E+ Sbjct: 389 IES 391 >1WL4-A nrPDB Length = 397 Score = 439 bits (1129), Expect = e-123, Method: Composition-based stats. Identities = 130/423 (30%), Positives = 203/423 (47%), Gaps = 41/423 (9%) Query: 54 VVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS 113 VV+V RT + + DL + +L R +V E V +IFG V+ Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67 Query: 114 NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPI 173 N R+A++GAG PA + M C S +A+ V I G ++VAGG+E MS P Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127 Query: 174 RHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAA 233 + L +G+ + L + L ++ + MG +A+ +A Sbjct: 128 ---------LAYLRTGVKIGE-MPLTDSILCDGL-------TDAFHNCHMGITAENVAKK 170 Query: 234 FAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKV---PGKDTVTKDNGIR-PSSLEQ 288 + VSR +QD+ A+ S + + AQ G ++VP V G V D R S++E Sbjct: 171 WQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEA 230 Query: 289 MAKLKPAFIKPY-GTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDP 347 M+KLKP F+ GTVT AN+S + DGA+A+++M + +A G P A + + V +P Sbjct: 231 MSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEP 290 Query: 348 KDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKT 407 + +GP A + + KAG ++ D+D FE +EAF+ A K + + Sbjct: 291 S-IMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNP---------- 339 Query: 408 KVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAM 467 EK N GG+++LGHP GA+GCR+++ + L + G G+ A C GG G AM Sbjct: 340 -------EKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAM 392 Query: 468 IVE 470 V+ Sbjct: 393 CVQ 395 >4NZS-A nrPDB Length = 399 Score = 433 bits (1114), Expect = e-122, Method: Composition-based stats. Identities = 149/425 (35%), Positives = 205/425 (48%), Gaps = 41/425 (9%) Query: 52 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQ-EV 110 R VVVV GVRT G S KD+ P +L + L R V + V +++FG VIQ E Sbjct: 8 REVVVVSGVRTAIGTFGGSLKDVAPAELGALVVREALARAQVSGDDVGHVVFGNVIQTEP 67 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 + + R AA+ G + PA TV C S QA+ + I G DV + GG E MS Sbjct: 68 RDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAESMSR 127 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 P L A G R+ + L A+ + MG +A+ + Sbjct: 128 APY------------LAPAARWGARMG-----DAGLVDMMLGALHDPFHRIHMGVTAENV 170 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---TVTKDNGIR-PSS 285 A + +SR +QDE AL SH A A G D +VP G+ T D +R ++ Sbjct: 171 AKEYDISRAQQDEAALESHRRASAAIKAGYFKDQIVPVVSKGRKGDVTFDTDEHVRHDAT 230 Query: 286 LEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQ 345 ++ M KL+P F+K GTVTA N+S L D A+A+++M +A G KP A L + + Sbjct: 231 IDDMTKLRPVFVKENGTVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGV 290 Query: 346 DPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGR 405 DPK + +GP AT LE+AGL ++D+D E +EAF+ Q A KA+ D Sbjct: 291 DPK-AMGIGPVPATKIALERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPA------- 342 Query: 406 KTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGH 465 K N G +SLGHP GATG + + A + L + G+Y LV C GGQG Sbjct: 343 ----------KVNPNGSGISLGHPIGATGALITVKALHELNRVQGRYALVTMCIGGGQGI 392 Query: 466 AMIVE 470 A I E Sbjct: 393 AAIFE 397 >4O9A-A nrPDB Length = 398 Score = 431 bits (1109), Expect = e-121, Method: Composition-based stats. Identities = 127/424 (29%), Positives = 203/424 (47%), Gaps = 41/424 (9%) Query: 53 NVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKT 112 +VV+V RT G S + +L + L R V E V +I G V+ Sbjct: 8 DVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAGSG 67 Query: 113 SNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVP 172 N AR+AA+ AG PA T+ S +A+ I +G +++VAGG E MS P Sbjct: 68 QNPARQAAIKAGLPAMVPAMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAAP 127 Query: 173 IRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAA 232 ++ MG + + + + + MG +A+ +A Sbjct: 128 --------HVLPGSRDGFRMGDAKLVDTMI--------VDGLWDVYNQYHMGITAENVAK 171 Query: 233 AFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKDT----VTKDNGIRP-SSL 286 + ++R QDE+A+ S + A+ AQ G ++VP +P + D +R ++L Sbjct: 172 EYGITREAQDEFAVGSQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATL 231 Query: 287 EQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQD 346 + M+ LKPAF K GTVTAAN+S L DGA+A+++M+ KA +G P A ++ + D Sbjct: 232 DSMSGLKPAFDK-AGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVD 290 Query: 347 PKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRK 406 PK + +GP A+ + L +A T D+D E +EAF+ Q LA + M D Sbjct: 291 PK-VMGMGPVPASKRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWD---------- 339 Query: 407 TKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHA 466 K N GG++++GHP GA+GCR+++ + +++ + GL + C GG G A Sbjct: 340 -------TSKVNVNGGAIAIGHPIGASGCRILVTLLHEMKRRDAKKGLASLCIGGGMGVA 392 Query: 467 MIVE 470 + VE Sbjct: 393 LAVE 396 >4C2K-A nrPDB Length = 417 Score = 431 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 139/427 (32%), Positives = 207/427 (48%), Gaps = 41/427 (9%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 +R V VV RTPF G KD DL+ A L V E VD +I G V+Q Sbjct: 24 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 83 Query: 111 KTS-NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 + +AR L G +TPA T+ C S Q++ G I + +V++ GG E MS Sbjct: 84 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 143 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 P + G +L K + ++++ M +A+ Sbjct: 144 QAPYCV------------RNVRFGTKLGSDIKLEDSLWV----SLTDQHVQLPMAMTAEN 187 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP---GKDTVTKDNGIRP-S 284 LA +SR E D+YAL+S K A D G +D + P +V GK T+ D RP + Sbjct: 188 LAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQT 247 Query: 285 SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS 344 +LEQ+ KL P F K GTVTA N+S + DGA A++I +E+ + P A + + Sbjct: 248 TLEQLQKLPPVF-KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG 306 Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMG 404 DP + +GP A L+KAGL++ D+D E +EAF+ Q LA +++D D Sbjct: 307 CDPS-IMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLD-------- 357 Query: 405 RKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQG 464 + K N GG+++LGHP G +G R+ + LR+ GG+Y + +AC GGQG Sbjct: 358 ---------ISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQG 408 Query: 465 HAMIVEA 471 A+I+++ Sbjct: 409 IAVIIQS 415 >4WYS-A nrPDB Length = 405 Score = 426 bits (1096), Expect = e-120, Method: Composition-based stats. Identities = 134/425 (31%), Positives = 199/425 (46%), Gaps = 39/425 (9%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 ++N V+V VRT S DL + + R + + VD +I G V+Q Sbjct: 4 MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAG 63 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 N AR+A L +G ++ TV C S +++ I +GQ IVAGG+E MS Sbjct: 64 LGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSL 123 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 P K R G RL + + A + MG +A+ + Sbjct: 124 APYLLDAKARS-----------GYRLGDGQVYDVILRDGLMCATHGY----HMGITAENV 168 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKD---TVTKDNGIR-PSS 285 A + ++R QDE AL S A A + G +++VP V + ++D + S+ Sbjct: 169 AKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANST 228 Query: 286 LEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQ 345 E + L+PAF K GTVTA N+S + DGA+A++IM E ALA G P A ++ + Sbjct: 229 AEALGALRPAFDK-AGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGV 287 Query: 346 DPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGR 405 P + +GP AT K L+ AGL + DID E +EAF+ Q LA K + D Sbjct: 288 -PPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDS-------- 338 Query: 406 KTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGH 465 EK N GG+++LGHP GA+G R+++ + ++ GL C GGQG Sbjct: 339 ---------EKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGI 389 Query: 466 AMIVE 470 AM++E Sbjct: 390 AMVIE 394 >6ARG-A nrPDB Length = 399 Score = 424 bits (1089), Expect = e-119, Method: Composition-based stats. Identities = 140/428 (32%), Positives = 203/428 (47%), Gaps = 41/428 (9%) Query: 50 NIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRT-SVPKEVVDYIIFGTVIQ 108 ++ V +V RTP S L L A+ L + + V + FG VI Sbjct: 4 SLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVIS 63 Query: 109 EVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELM 168 N AR+ ALGAG + T TV C S +A+ G I +G DV+VAGG E M Sbjct: 64 ANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESM 123 Query: 169 SDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSAD 228 S+ P + +L G SL+ + L ++ E MG A+ Sbjct: 124 SNAP--------HYLPNLRTGAKYG-HQSLVDGIMKDGL-------TDAGKQELMGLQAE 167 Query: 229 RLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPG-----KDTVTKDNGIR 282 A SR +QDEYA+R++ A+ AQ GL ++ P ++PG TVT+D + Sbjct: 168 ECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPK 227 Query: 283 PSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMY 342 + E++ +KPAFI GTVTA NSS L DGA+A+++++E K + KP A + + Sbjct: 228 NLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGD 287 Query: 343 VSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENY 402 +Q P P A PK L+ AG+ + IDAFE +EAFS LAN K + Sbjct: 288 AAQQPSK-FTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGI------- 339 Query: 403 MGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGG 462 P EK N GG++++GHP GA+G R++ L+ + G+ G C GG Sbjct: 340 ----------PEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGG 389 Query: 463 QGHAMIVE 470 A++VE Sbjct: 390 GASALVVE 397 >3GOA-A nrPDB Length = 387 Score = 423 bits (1087), Expect = e-118, Method: Composition-based stats. Identities = 146/429 (34%), Positives = 211/429 (49%), Gaps = 53/429 (12%) Query: 51 IRNVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHRT-SVPKEVVDYIIFGTVIQ 108 + VV+VD +RTP S G +++++ DL+ + LL R S+ +D I +G V Q Sbjct: 1 MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQ 60 Query: 109 EVKTS-NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167 ++ N+AR AAL A PA TV C S+ QA+ +I +G V + GGVE Sbjct: 61 TLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEH 120 Query: 168 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227 M VP+ H L N AK+ G MG +A Sbjct: 121 MGHVPMSHGVDFHP-GLSRNVAKAAG----------------------------MMGLTA 151 Query: 228 DRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVPGKDTVTK----DNGIR 282 + L+ +SR QD++A RSH+ A A G +++P D V K D IR Sbjct: 152 EMLSRLHGISREMQDQFAARSHARAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIR 211 Query: 283 P-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFM 341 P +++E ++ L+PAF GTVTA SS L+DGA+AML+M+E +A +G KP+A +R Sbjct: 212 PETTVEALSTLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMA 271 Query: 342 YVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAEN 401 V DP + GP A+ L+KAGL+ +DID FE +EAF+ QIL K + Sbjct: 272 VVGCDPS-IMGYGPVPASKLALKKAGLSASDIDVFEMNEAFAAQILPCIKDLGL------ 324 Query: 402 YMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAG 461 EK N GG+++LGHP G +G R+ N + ++ Q+GL C Sbjct: 325 --------MEQIDEKINLNGGAIALGHPLGCSGARISTTLINLMERKDAQFGLATMCIGL 376 Query: 462 GQGHAMIVE 470 GQG A + E Sbjct: 377 GQGIATVFE 385 >5LP7-H nrPDB Length = 393 Score = 420 bits (1080), Expect = e-118, Method: Composition-based stats. Identities = 141/428 (32%), Positives = 216/428 (50%), Gaps = 41/428 (9%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 +R V+V RTPF G K++ +L + L + V + V+ + G V+Q Sbjct: 1 MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQQAGVSGDDVEGNVMGMVVQAG 60 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 +R+AA AG P+ T+ C S +A+T +I + D++VAGG+E MS+ Sbjct: 61 SGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGMESMSN 120 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 +P A G R+ + R + L + G++A Sbjct: 121 IPYAVP------------AGRWGARMG-DGELRDLMVYDGLTCAFDEVHMAVHGNTA--- 164 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGK----DTVTKDNGIRP-S 284 A +A+SR EQDE+ALRSH+ A KA DEG ++VP G+ + V KD IR + Sbjct: 165 AKEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRRDT 224 Query: 285 SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS 344 SL+Q+AKL P + G++TA N+ + DGA A ++M+EEKA +G +P A + F Sbjct: 225 SLDQLAKLAPIYASD-GSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFSTTG 283 Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMG 404 P +L P +A K+L+K GLT+ DID FE +EAF+ +L K + D Sbjct: 284 M-PAHELAAAPGFAINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFD-------- 334 Query: 405 RKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQG 464 LEK N GG+++LGHP GA+G R++M L++ GG G+ A C+ QG Sbjct: 335 ---------LEKVNVNGGAIALGHPIGASGARILMTLVYELKRRGGGLGVAAICSGAAQG 385 Query: 465 HAMIVEAY 472 A++V+ + Sbjct: 386 DAVLVQVH 393 >1WDK-C nrPDB Length = 390 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 147/430 (34%), Positives = 211/430 (49%), Gaps = 53/430 (12%) Query: 50 NIRNVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHRTS-VPKEVVDYIIFGTVI 107 N R+VV+VD RTP S G +++ D++ ++ +L R S V V+ +I+G V Sbjct: 3 NPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVN 62 Query: 108 QEVKTS-NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 Q ++ N+AR A+L + A TV+ C S+ A+ T I +G DV V GGVE Sbjct: 63 QTLEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVE 122 Query: 167 LMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHS 226 M V + H M ++ S MG + Sbjct: 123 HMGHVSMMHGVDPNPHM-----------------------------SLYAAKASGMMGLT 153 Query: 227 ADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKDTVTK----DNGI 281 A+ L +SR +QD +A+RSH LA KA EG D ++P + ++ K D I Sbjct: 154 AEMLGKMHGISREQQDAFAVRSHQLAHKATVEGKFKDEIIPMQGYDENGFLKIFDYDETI 213 Query: 282 RP-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDF 340 RP ++LE +A LKPAF GTVTA SS +TDGAS M++M+ ++A +G +P A +R Sbjct: 214 RPDTTLESLAALKPAFNPKGGTVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSM 273 Query: 341 MYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAE 400 DP + GP AT K L++AGL M DID E +EAF+ Q L K + Sbjct: 274 AVAGVDPA-IMGYGPVPATQKALKRAGLNMADIDFIELNEAFAAQALPVLKDL------- 325 Query: 401 NYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAA 460 KV EK N GG+++LGHPFG +G R+ N +++ GG +GL C Sbjct: 326 -------KVLDKMNEKVNLHGGAIALGHPFGCSGARISGTLLNVMKQNGGTFGLSTMCIG 378 Query: 461 GGQGHAMIVE 470 GQG A + E Sbjct: 379 LGQGIATVFE 388 >2IIK-A nrPDB Length = 418 Score = 416 bits (1069), Expect = e-116, Method: Composition-based stats. Identities = 146/433 (33%), Positives = 212/433 (48%), Gaps = 59/433 (13%) Query: 53 NVVVVDGVRTPFLLSG-TSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVK 111 +VVVV G RT +G +KD P +L A +T +L ++ E + I G V+Q Sbjct: 31 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 90 Query: 112 TSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDV 171 + +AR A + + P TV C S QA+ + G I +G D+ +A GVE MS Sbjct: 91 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 150 Query: 172 PIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLA 231 D ++ RL K R + MG +++ +A Sbjct: 151 -------------DRGNPGNITSRLMEKEKARDCLIP--------------MGITSENVA 183 Query: 232 AAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVPGKD--------TVTKDNGIR 282 F +SR +QD +AL S A +AQ +G ++VP D TVT+D GIR Sbjct: 184 ERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIR 243 Query: 283 P-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFM 341 P +++E +AKLKPAF K G+ TA NSS ++DGA+A+L+ KA +G LR + Sbjct: 244 PSTTMEGLAKLKPAF-KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYA 302 Query: 342 YVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAEN 401 V P D + +GP YA P L+KAGLT++D+D FE +EAF+ Q + + Sbjct: 303 VVGV-PPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRL------ 355 Query: 402 YMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQ-YGLVAACAA 460 P EK N GG+++LGHP G TG R V+ N L++ G + YG+V+ C Sbjct: 356 -----------PPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIG 404 Query: 461 GGQGHAMIVEAYP 473 G G A + E YP Sbjct: 405 TGMGAAAVFE-YP 416 >5CBQ-A nrPDB Length = 413 Score = 416 bits (1068), Expect = e-116, Method: Composition-based stats. Identities = 142/428 (33%), Positives = 198/428 (46%), Gaps = 34/428 (7%) Query: 50 NIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQE 109 ++R+ V+ + VRTP G ++ L DL AL GLL RT + + V+ +I G Sbjct: 8 SMRDAVICEPVRTPIGRYGGMFRSLTAVDLGVTALKGLLERTGIAADQVEDVILGHCYPN 67 Query: 110 VKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 + + R AL AG P V C S QA+ + SG D++VAGG E MS Sbjct: 68 SEAPAIGRVVALDAGLPITVPGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAESMS 127 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 +V + G + + M +A+ Sbjct: 128 NVAFY------------STDMRWGGARTGVQIHDGLARGRTTAGGKFHPVPGGMLETAEN 175 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVP---GKDTVTKDNGIR-PS 284 L + +SR EQDE A+RSH A AQ EG+L +++P V G++T++ D R + Sbjct: 176 LRREYHISRTEQDELAVRSHQRAVAAQSEGVLAEEIIPVPVRTRDGEETISVDEHPRADT 235 Query: 285 SLEQMAKLKPAFIK--PYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMY 342 ++E +AKLKP +K P TVTA NSS D AS ++ EKA +G KP L + Sbjct: 236 TVEALAKLKPVLLKQDPEATVTAGNSSGQNDAASMCIVTTPEKAAELGLKPLVRLVSWGS 295 Query: 343 VSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENY 402 P D + +GP AT L KAGLT+ DID E +EAF+ Q LA + Sbjct: 296 AGVAP-DLMGIGPVPATEVALAKAGLTLADIDLIELNEAFAAQALAVMRE---------- 344 Query: 403 MGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGG 462 K G E+ N G +SLGHP GATG R++ A L + +YGL C GG Sbjct: 345 ----WKFGEADHERTNVRGSGISLGHPVGATGGRMLATLARELHRREARYGLETMCIGGG 400 Query: 463 QGHAMIVE 470 QG A + E Sbjct: 401 QGLAAVFE 408 >5XYJ-B nrPDB Length = 408 Score = 411 bits (1057), Expect = e-115, Method: Composition-based stats. Identities = 130/428 (30%), Positives = 204/428 (47%), Gaps = 43/428 (10%) Query: 52 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSV--PKEVVDYIIFGTVIQE 109 +NV +V RTP S +L AL G L + + D IIFG V+ Sbjct: 13 QNVYIVSTARTPIGSFQGSLSSKTAVELGAVALKGALAKVPELDASKDFDEIIFGNVLSA 72 Query: 110 VKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 AR+ AL AG S+ A TV SA +A+ G I G DV+VAGG E M+ Sbjct: 73 NLGQAPARQVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVAGGCESMT 132 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 + P M GQ + + R +++ MG A++ Sbjct: 133 NAPY--------YMPAARAGAKFGQTVLVDGVER--------DGLNDAYDGLAMGVHAEK 176 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKDT-----VTKDNGIRP 283 A + ++R +QD +A+ S+ ++K+Q EG +++VP + G VTKD Sbjct: 177 CARDWDITREQQDNFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEPAR 236 Query: 284 SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYV 343 +E++ + F K GTVTAAN+S + DGA+A+++++E+ KP A ++ + Sbjct: 237 LHVEKLRSARTVFQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEA 296 Query: 344 SQDPKDQLLLGPTYATPKVLEKAGLT-MNDIDAFEFHEAFSGQILANFKAMDSDWFAENY 402 + P D P+ A PK L+ AG+ +N +D FEF+EAFS L N K + D Sbjct: 297 AHQPAD-FTWAPSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDP----- 350 Query: 403 MGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGG 462 K N +GG+++LGHP G +G R+V+ + L++EGG+ G+ A C GG Sbjct: 351 ------------SKVNVYGGAVALGHPLGCSGARVVVTLLSILQQEGGKIGVAAICNGGG 398 Query: 463 QGHAMIVE 470 ++++E Sbjct: 399 GASSIVIE 406 >6BJB-A nrPDB Length = 393 Score = 404 bits (1037), Expect = e-113, Method: Composition-based stats. Identities = 130/430 (30%), Positives = 195/430 (45%), Gaps = 44/430 (10%) Query: 45 TLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFG 104 T ++P I +VV V RTP +++ ++ L R AL G L +V +V G Sbjct: 2 TGSRP-ITDVVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIG 60 Query: 105 TVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGG 164 V+ AR+ LGAG T V S +A+ ++ +++VAGG Sbjct: 61 VVVPSNAGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGG 120 Query: 165 VELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMG 224 +E MS VP R LI +++ MG Sbjct: 121 MESMSCVPFYLPRGEIPFGGTK-----------LIDGI-------PRDGLNDVYNDILMG 162 Query: 225 HSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKD---TVTKDNG 280 AD++A FA++R EQD+YA+ S+ + A EG+ +++P +V TV +D Sbjct: 163 ACADKVAKQFAITREEQDKYAILSYKRSAAAWKEGIFAKEIIPLEVTQGKKTITVEEDEE 222 Query: 281 IRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDF 340 + + E++ KLKPAF G+VTAAN+S L DGA+ +++ + A G KP A + + Sbjct: 223 YKKVNFEKIPKLKPAFTSE-GSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAY 281 Query: 341 MYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAE 400 + P D + P PKVL+ AGL + DID +E +EAF+ L K + D Sbjct: 282 GDAATHPID-FGIAPASVIPKVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDE--- 337 Query: 401 NYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAA 460 K N GG++SLGHP G +G R+V + L+ GQ G A C Sbjct: 338 --------------SKVNIHGGAVSLGHPIGMSGARIVGHLVHTLKP--GQKGCAAICNG 381 Query: 461 GGQGHAMIVE 470 GG MI+E Sbjct: 382 GGGAGGMIIE 391 >6BJA-A nrPDB Length = 397 Score = 401 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 112/425 (26%), Positives = 193/425 (45%), Gaps = 44/425 (10%) Query: 52 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVK 111 ++V ++ VRTP ++ L DL + R+ +P ++ I G V+ Sbjct: 9 KDVYILSAVRTPIASFRSTLTSLSAVDLGIVVTKEAIKRSLLPSSAIEETIVGNVLSAGL 68 Query: 112 TSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDV 171 N+AR+ ++ + + T+ C S+ +A+ G I G ++VA G E MS+ Sbjct: 69 GQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSESMSNA 128 Query: 172 PIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLA 231 P R + QR L+ + + MG A++ Sbjct: 129 PFYVPRGEIPFGG--VQLVDALQRDGLMDSIEY----------------QPMGLCAEKTV 170 Query: 232 AAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVPGKD----TVTKDNGIRPSSL 286 +A +R + D YA+ S+ A+ A EG + +VVP VP K +T+D + Sbjct: 171 KDYAFTREQLDAYAIESYRKAEHAWKEGAFNKEVVPVSVPQKRGSKVVLTEDEEYKRLIP 230 Query: 287 EQMAKLKPAFIKPY-GTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQ 345 E++ L PAF+K GT+TAAN+S + DGA+A ++ + E KP A + + Sbjct: 231 EKVPALHPAFLKDGSGTITAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGV 290 Query: 346 DPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGR 405 +P D + P A ++L ++GL I +E +EAFS LA K + D Sbjct: 291 EPID-FTVAPALAVKQLLSQSGLDEESIALWEINEAFSVTGLAFIKELRLDP-------- 341 Query: 406 KTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGH 465 ++ N GG+++LGHP GA+G R+V+ + L+ + + G+ A C GG+ Sbjct: 342 ---------KRVNVRGGAVALGHPLGASGARIVVTLVHALKSD--ELGVAAICNGGGEAS 390 Query: 466 AMIVE 470 A++++ Sbjct: 391 AILIK 395 >2C7Y-A nrPDB Length = 404 Score = 397 bits (1021), Expect = e-111, Method: Composition-based stats. Identities = 133/433 (30%), Positives = 200/433 (46%), Gaps = 61/433 (14%) Query: 53 NVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV- 110 +VV+V RTP S ++KD P DL L L+ +T++ V I+ GTV+ Sbjct: 14 DVVIVAAHRTPLCKSKRGNFKDTYPDDLLAPVLRALIEKTNLNPSEVGDIVVGTVLAPGS 73 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 + ++ R AA AGF + TV C S QA+ I +G D+ + G+E M+ Sbjct: 74 QRASECRMAAFYAGFPETVAVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTT 133 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 P+ + + +A++ MG +++ + Sbjct: 134 NPMAWEGSVNPAVKKFAQAQN---------------------------CLLPMGVTSENV 166 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---------TVTKDNG 280 A F VSR EQD+ A+ SH A A G D ++P K D TV+ D+G Sbjct: 167 AQRFGVSRQEQDQAAVDSHRKAAAATAAGKFKDEIIPVKTKLVDPKTGDEKPITVSVDDG 226 Query: 281 IRP-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRD 339 IRP ++L + KLKP F K GT TA NSS ++DGA A+L+M A+ G R Sbjct: 227 IRPTTTLASLGKLKPVF-KKDGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPVLGVFRT 285 Query: 340 FMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFA 399 F V DP + +GP A P ++ AGL ++DID FE +EAF+ Q + + D Sbjct: 286 FAAVGVDPA-IMGIGPAVAIPAAVKAAGLELDDIDLFEINEAFASQFVYCRNKLGLDP-- 342 Query: 400 ENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEG--GQYGLVAA 457 EK N GG++++GHP GATG R V + +++ G ++G+V+ Sbjct: 343 ---------------EKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGKDCRFGVVSM 387 Query: 458 CAAGGQGHAMIVE 470 C G G A + E Sbjct: 388 CIGTGMGAAAVFE 400 >2WUA-A nrPDB Length = 440 Score = 392 bits (1008), Expect = e-109, Method: Composition-based stats. Identities = 126/433 (29%), Positives = 200/433 (46%), Gaps = 61/433 (14%) Query: 53 NVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV- 110 +VV+V R+P + KD P D+ L L+ +T++ V I+ G+V+ Sbjct: 34 DVVIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEVGDIVVGSVLGAGS 93 Query: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 + ++ R AA AGF + P TV C S QA+ I +G D+ + G+E M+ Sbjct: 94 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTA 153 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRL 230 P+ + + + +A+ MG +++ + Sbjct: 154 NPMAWEGSVNPKVKTMAQAQD---------------------------CLLPMGITSENV 186 Query: 231 AAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---------TVTKDNG 280 A F+++R EQD+ A+ SH A G D ++P K D T++ D+G Sbjct: 187 AQKFSITRQEQDQAAVGSHRKTAAATAAGRFKDEIIPIKTKIVDPKTGDEKPVTISVDDG 246 Query: 281 IRP-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRD 339 IRP +SL +AKLKP F K G+ TA SS ++DGA A+L+M AL G R Sbjct: 247 IRPGTSLADLAKLKPVFRKD-GSTTAGTSSQVSDGAGAVLLMKRSIALQKGLPILGVFRT 305 Query: 340 FMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFA 399 F V P + +GP A P ++ AGL ++DID FE +EAF+ Q + K ++ D Sbjct: 306 FAAVGV-PPSIMGIGPAVAIPAAVKAAGLQIDDIDLFEINEAFASQFVYCQKKLEIDP-- 362 Query: 400 ENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEG--GQYGLVAA 457 +K N GG++++GHP GATG R V + +++ G ++G+V+ Sbjct: 363 ---------------QKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGRDCRFGVVSM 407 Query: 458 CAAGGQGHAMIVE 470 C G G A + E Sbjct: 408 CIGTGMGAAAVFE 420 >1PXT-A nrPDB Length = 390 Score = 381 bits (977), Expect = e-106, Method: Composition-based stats. Identities = 127/432 (29%), Positives = 189/432 (43%), Gaps = 53/432 (12%) Query: 46 LAKPNIRNVVVVDGVRTPFLL-SGTSYKDLMPHDLARAALTGLLHRTSVPK----EVVDY 100 L + +VV+V R+ ++KD+ L L + R P +++ Sbjct: 1 LLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEE 60 Query: 101 IIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVI 160 + G V+ + R A L +G TP + C S A+ I GQ D+ Sbjct: 61 VACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIG 120 Query: 161 VAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTS 220 +A GVE M++ + +G + EL E Sbjct: 121 LALGVESMTN--------------NYKNVNPLGM-----------ISSEELQKNREAKKC 155 Query: 221 -ETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKDTVTKD 278 MG + + +AA F +SR +QDE+A S+ A KA++EGL D ++P K+P D Sbjct: 156 LIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSD 215 Query: 279 NGIRP-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYL 337 G RP + E ++ ++PAFIK GT TA N+S ++DG + +L+ A + Sbjct: 216 EGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRY 275 Query: 338 RDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDW 397 DF V P + + +GP YA PKVLE GL + DID FE +EAF+ Q L + D Sbjct: 276 IDFQTVGV-PPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGID- 333 Query: 398 FAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAA 457 L K N GG+++LGHP G TG R V L+K+ Q G+V+ Sbjct: 334 ----------------LNKVNPRGGAIALGHPLGCTGARQVATILRELKKD--QIGVVSM 375 Query: 458 CAAGGQGHAMIV 469 C G G A I Sbjct: 376 CIGTGMGAAAIF 387 >4UBW-A nrPDB Length = 399 Score = 366 bits (939), Expect = e-101, Method: Composition-based stats. Identities = 124/432 (28%), Positives = 190/432 (43%), Gaps = 63/432 (14%) Query: 55 VVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVP----KEVVDYIIFGTVIQEV 110 V+V+ R+P L +L A ++ + + V+ +I G V Q Sbjct: 13 VIVEATRSPIGKRNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGCVTQFG 72 Query: 111 KT-SNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 + +N++R A L AG + A TV C S QA GLIA+G DV +A G+E MS Sbjct: 73 EQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACGIEAMS 132 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 V + G SLI ++ P +A+R Sbjct: 133 RV---------------GLGANAGPDRSLIRAQSWDIDLPNQF------------EAAER 165 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVPGKDT----------VTKD 278 +A ++R + D + L S A++A EG ++ P + P D V +D Sbjct: 166 IAKRRGITREDVDVFGLESQRRAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRD 225 Query: 279 NGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLR 338 G+R +++ + +LKP G TA SS ++DGA+A+L M E A A G P+A + Sbjct: 226 QGLRETTMAGLGELKPVL--EGGIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIV 283 Query: 339 DFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWF 398 V +P L GP +T KVLEKAG+ + DID E +EAF+ +L+ Sbjct: 284 AQALVGAEPYYHLD-GPVQSTAKVLEKAGMKIGDIDIVEINEAFASVVLS---------- 332 Query: 399 AENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAAC 458 +V P +++ N GG+++LGHP G TG RL+ A + L + L+ C Sbjct: 333 -------WARVHEPDMDRVNVNGGAIALGHPVGCTGSRLITTALHELERTDQSLALITMC 385 Query: 459 AAGGQGHAMIVE 470 A G I+E Sbjct: 386 AGGALSTGTIIE 397 >3SVK-A nrPDB Length = 407 Score = 361 bits (926), Expect = e-100, Method: Composition-based stats. Identities = 126/445 (28%), Positives = 191/445 (42%), Gaps = 72/445 (16%) Query: 52 RNVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHR-TSVPKEVVDYIIFGTVIQE 109 + + +RTP S ++ P +L + L R + + ++ +I G V Sbjct: 7 EEAFIYEAIRTPRGKQKNGSLTEVKPLNLVVGLVDELRRRYPDLDETLISDMILGVVSPV 66 Query: 110 V-KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELM 168 + ++AR A L AG + T + C S +A+ T + SG D+++AGGVE M Sbjct: 67 GDQGGDIARTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESM 126 Query: 169 SDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSAD 228 S VP+ + N +R F+ G AD Sbjct: 127 SRVPMGSDGGAWATDPETN--------------YRIGFVPQ--------------GIGAD 158 Query: 229 RLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFK-VPGKDTVTKDNGIRP-SS 285 +A SR + D YALRS A A G VVP + G + D +RP ++ Sbjct: 159 LIATLEGFSREDVDAYALRSQQKAAAAWSGGYFAKSVVPVRDQNGLVILDHDEHMRPDTT 218 Query: 286 LEQMAKLKPAFI--------------------KPYGTVTAANSSFLTDGASAMLIMAEEK 325 +E +AKLK AF K T NSS + DGA+ +L+ +E+ Sbjct: 219 MEGLAKLKTAFDGVGEMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKA 278 Query: 326 ALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQ 385 + G P+A + DP +L GPT AT KVL++AGLT++DID FE +EAF+ Sbjct: 279 GKSQGLTPRARIVATATSGSDPV-IMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASV 337 Query: 386 ILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRL 445 +L K ++ P EK N GG++++GHP GATG + + L Sbjct: 338 VLKFQKDLNI-----------------PDEKLNVNGGAIAMGHPLGATGAMITGTMVDEL 380 Query: 446 RKEGGQYGLVAACAAGGQGHAMIVE 470 + + L+ C GG G A I+E Sbjct: 381 ERRNARRALITLCIGGGMGVATIIE 405 >4B3J-C nrPDB Length = 403 Score = 354 bits (907), Expect = 7e-98, Method: Composition-based stats. Identities = 124/445 (27%), Positives = 190/445 (42%), Gaps = 72/445 (16%) Query: 52 RNVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHR-TSVPKEVVDYIIFGTVIQE 109 + + +RTP S ++ P L + L R + + ++ +I G V Sbjct: 3 EEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLIDELRKRHPDLDENLISDVILGCVSPV 62 Query: 110 V-KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELM 168 + ++AR A L +G + + C S +A+ T + SG D+++AGGVE M Sbjct: 63 GDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESM 122 Query: 169 SDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSAD 228 S VP+ + +MG L + + F+ AD Sbjct: 123 SRVPMG------------SDGGAMG--LDPATNYDVMFVPQS--------------IGAD 154 Query: 229 RLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFK-VPGKDTVTKDNGIRP-SS 285 +A SR + D YALRS A +A G VVP + G + D +RP ++ Sbjct: 155 LIATIEGFSREDVDAYALRSQQKAAEAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPDTT 214 Query: 286 LEQMAKLKPAF--------------------IKPYGTVTAANSSFLTDGASAMLIMAEEK 325 E +AKLKPAF K T NSS + DGA+ ++I + Sbjct: 215 KEGLAKLKPAFEGLAALGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAA 274 Query: 326 ALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQ 385 G P+A + DP +L GPT AT KVL++AGLT++DID FE +EAF+ Sbjct: 275 GKLQGLTPRARIVATATSGADPV-IMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASV 333 Query: 386 ILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRL 445 +L K ++ P EK N GG++++GHP GATG ++ + L Sbjct: 334 VLKFQKDLNI-----------------PDEKLNVNGGAIAMGHPLGATGAMILGTMVDEL 376 Query: 446 RKEGGQYGLVAACAAGGQGHAMIVE 470 + + L+ C GG G A I+E Sbjct: 377 ERRNARRALITLCIGGGMGVATIIE 401 >6HRV-A nrPDB Length = 421 Score = 275 bits (704), Expect = 2e-74, Method: Composition-based stats. Identities = 93/438 (21%), Positives = 154/438 (35%), Gaps = 61/438 (13%) Query: 51 IRNVVVVDGV-RTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQE 109 +RN V V GV T F G +D+ D+A+ A L + + G V + Sbjct: 12 LRNRVFVIGVGMTKFEKPGA--RDIDYPDMAKEAGQRALADAGIKYSAIQQACVGYVYGD 69 Query: 110 VKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 A +LG P V C + + A+ G LI G D ++A G E M Sbjct: 70 STCGQRAIYHSLGL---SGIPIINVNNNCSTGSTALFMGRQLIQGGLADCVLALGFEKME 126 Query: 170 DVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADR 229 S + + ++ M + + ++ P P + G++ Sbjct: 127 R----GSLSSKYM----DRTNPMDKHMEVMINRYGLAAVPAAP--------QMFGNAG-- 168 Query: 230 LAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQM 289 R ++Y + AK A S P+ + +D SLEQ+ Sbjct: 169 --------REHMEKYGTKPEHFAKVAWKNHKHSTNNPY------SQFQDEY----SLEQV 210 Query: 290 AKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAY-------LRDFMY 342 + F +T +DGA A ++ +E G + KA + D Sbjct: 211 IDSRKVF----EFLTLLQCCPTSDGAGAAVLASESFVRRNGLEKKAVEIVAQEMVTDLST 266 Query: 343 VSQDPKDQLLLG---PTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDS-DWF 398 ++ ++G A + + AG+ +D+D E H+ FS L ++A+ Sbjct: 267 TFEENSCMKMVGYDMTRLAAERCYDTAGVKPSDVDVIELHDCFSANELITYEALGLCPEG 326 Query: 399 AENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGL---- 454 + + N GG +S GHP GATG +LR E G + Sbjct: 327 KAGELIDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRAEAGPRQVPGAK 386 Query: 455 VAACAAGGQGHAMIVEAY 472 +A G G A++V Y Sbjct: 387 LALQHNIGLGGAVVVTLY 404 >5LNQ-A nrPDB Length = 457 Score = 206 bits (525), Expect = 1e-53, Method: Composition-based stats. Identities = 88/439 (20%), Positives = 154/439 (35%), Gaps = 81/439 (18%) Query: 54 VVVVDGVRTPFLLSGTSY------------KDLMPHDLARAALTGLLHRTSVPK--EVVD 99 V +V G TPF+ G+ K++ ++ + G + + + +VD Sbjct: 31 VFIVGGHITPFVGKGSPLFIDKKHPDFGKKKNMTLEEILATTVQGTMEHSGLSGREGIVD 90 Query: 100 YIIFGTVIQEVKTSN----VAREAALGAGFSDKT------PAHTVTMACISANQAMTTGV 149 ++ G + E+ +S A +L G + PA V A S A+ + + Sbjct: 91 QVVVGNFLGELFSSQGHLGPAAIGSLTYGQAGSKNPLMYKPAMRVEGAAASGGLAVISAM 150 Query: 150 GLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAP 209 + SG D+ +A GVE+ + R D QR + F F L Sbjct: 151 NALKSGSADITLAVGVEVQTTASARVGGDYLARAADY-------QRQRQLDDFTFPCLFA 203 Query: 210 ELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKV 269 + TM +A +A KA G + + Sbjct: 204 KRMKYIAEHNHFTMEDTA----------------------RVAAKAYANGNKNPLAHM-- 239 Query: 270 PGKDTVTKDNGIRPSSLEQMAKLKPAFIKPYGTVT------AANSSFLTDGASAMLIMAE 323 R + EQ P+ +K G T + S ++DG + +++ E Sbjct: 240 ----------HTRKLTFEQCNGEDPSNVKFLGNETYKEYLRMTDCSQVSDGGAGVVLANE 289 Query: 324 EKALAMGYKP--------KAYLRDFMYVSQDPKDQL-LLGPTYATPKVLEKAGLTMNDID 374 E MG P K+ + +DP D + A K L A + +D++ Sbjct: 290 EGLRKMGLSPNDSRLVEIKSIACAVSNLYEDPDDACCMFTSRQAAQKALSMANIKPSDLN 349 Query: 375 AFEFHEAFSGQILANFKAMDS-DWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGAT 433 E H+ F+ + ++A+ ++ + R L N GG LS GHP GAT Sbjct: 350 VAEVHDCFTIAEMLMYEALGIAEYGHAKDLIRNGDTTLEGRIPVNTGGGLLSFGHPVGAT 409 Query: 434 GCRLVMAAANRLRKEGGQY 452 G + +M +++ + Y Sbjct: 410 GIKQIMEVYRQMKGQCEAY 428 >6ESQ-A nrPDB Length = 392 Score = 189 bits (479), Expect = 3e-48, Method: Composition-based stats. Identities = 86/435 (19%), Positives = 148/435 (34%), Gaps = 77/435 (17%) Query: 51 IRNVVVVDGVRTPFL-LSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGT---- 105 +R+V ++ +T F L S++ DL A + +V +D + G Sbjct: 1 MRDVAIIGYGQTKFGELWEDSFR-----DLIVEAGVKAIKDANVDGGDIDAMYIGNMSGG 55 Query: 106 --VIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAG 163 V QE S +A A L + P V AC S + A+ + V +ASG DV++AG Sbjct: 56 LFVGQEHIASLIADHAGL-----NPVPCTRVEAACASGSLALRSAVLSVASGHHDVVLAG 110 Query: 164 GVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETM 223 GVE M+DV + S + F P++ M Sbjct: 111 GVEKMTDV-----------------EDATAAIASASDQEWEAFFGATFPSLYAMMARRYM 153 Query: 224 GHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRP 283 + ++ E +++ +H A K + Sbjct: 154 --------YQYGLTIEELSMWSVIAHENATKNKYA--------------------QFGFK 185 Query: 284 SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYV 343 ++LEQ+ P +T + S ++DGASA+++ +KA K + Sbjct: 186 TTLEQVMNASPVADP----LTLMHCSPVSDGASALIVCDADKAEEFAPKDEIIYIKASTQ 241 Query: 344 SQD-------PKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDS- 395 + D L A+ K + A + ID E H+ F+ L + + Sbjct: 242 ASDTIALHDREDMTTLNAAKVASEKAYKLAKIAPEKIDVAEVHDCFAINGLILVEDLGFC 301 Query: 396 --DWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRK-EGGQY 452 + K ++ N GG + GH GATG R V +L++ + + Sbjct: 302 KKGDAGKVIDEGKIRIDYDDFVTVNPSGGLKAAGHALGATGIRQVGELYWQLKQDKECKD 361 Query: 453 GLVAACAAGGQGHAM 467 G + Sbjct: 362 RQATIKNGYGIAANV 376 >4BI9-A nrPDB Length = 454 Score = 173 bits (437), Expect = 2e-43, Method: Composition-based stats. Identities = 91/478 (19%), Positives = 166/478 (34%), Gaps = 101/478 (21%) Query: 43 KKTLAKPNIRNVVVVDGVRTPFLLSGTSY------------KDLMPHDLARAALTGLLHR 90 ++T + + + V VV G T F+ G+ ++ +L ++ G L Sbjct: 19 RRTSSTFSAKRVFVVGGHITTFVGKGSPLFIDKKHPDFGKKENKTLEELLAESINGALQN 78 Query: 91 TSV---PKEVVDYIIFGTVIQEVKTSN----VAREAALGAGFSD---KTPAHTVTMACIS 140 T + +VD ++ G + E+ +S A +L S PA V AC S Sbjct: 79 TGLHDGRAALVDKLVVGNFLGELFSSQGHLGPAAVGSLSGSNSSAFLNKPAVRVEGACAS 138 Query: 141 ANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLIS 200 A+ + + +G + +A GVE+ + V ++ D + +R + Sbjct: 139 GGLAVQSAWEALLAGTSQIALAVGVEVQTTV-------SARVGGDYLARAAHYKRQRQLD 191 Query: 201 KFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGL 260 F F L +A K Q+ G Sbjct: 192 DFTFPCL------------------------------------FA----RRMKAIQEAGH 211 Query: 261 LS------DVVPFKVPGKDTVTKDNGIRPSSLE---QMAKLKPAFI-----KPYGTVTAA 306 + G R +L+ Q + P F+ KP+ + Sbjct: 212 FTMEDAAYVAAKAYASGNRNPLAHMHARKVTLDFCTQASDKNPNFLGNEIYKPF--LRTT 269 Query: 307 NSSFLTDGASAMLIMAEEKALAMGYKP--------KAYLRDFMYVSQDPKDQLLLGPTY- 357 + S ++DG +A+++ +EE +G P K+ + +D D + + Sbjct: 270 DCSQVSDGGAAVILASEEGLQKLGLSPNDNRLVEIKSLASAAGNLYEDSPDLTRMTTSMV 329 Query: 358 ATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDS-DWFAENYMGRKTKVGLPPLEK 416 A L AG+ + E H+ F+ L ++A+ ++ + R L Sbjct: 330 AARTALSMAGVKPEQLQVAEVHDCFTIAELLMYEALGIAEYGGAGALIRSGATALDGRIP 389 Query: 417 FNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQY------GLVAACAAGGQGHAMI 468 N GG LS GHP GATG + V+ +++ + G+Y G+ A GG + Sbjct: 390 VNTGGGLLSFGHPVGATGVKQVLEVYRQMKGQCGEYQMKNIPGIGATLNMGGDDKTAV 447 >4YZO-A nrPDB Length = 373 Score = 160 bits (404), Expect = 1e-39, Method: Composition-based stats. Identities = 91/433 (21%), Positives = 156/433 (36%), Gaps = 83/433 (19%) Query: 54 VVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS 113 V +VD T F + DL + LL +DY+I Sbjct: 2 VAIVDVGITKFGKRKENI-----FDLVKEVTEKLLK------YDIDYVIVSNSYSGEFNQ 50 Query: 114 NVAREAALGAGFS-DKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVP 172 + + + D P+ V S A+ L+ S + + ++ GVE MS Sbjct: 51 TSGLSSLITTYLNLDYVPSLRVDNTSGSGGSAILVAKSLLESKEANTVLVVGVEKMS--- 107 Query: 173 IRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAA 232 +K R++ ++ +R++ LP+++ S E M Sbjct: 108 ---EKKTREVTKIISSLLPFEERIA------------SLPSLASISAIEYM--------R 144 Query: 233 AFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKL 292 F R S+A+ A + PF + +LE++ Sbjct: 145 KFNAPRE----------SIAQVAVKNHYNGSLNPFAHIQ----------KRVTLEEVLNS 184 Query: 293 KPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDF------MYVSQD 346 P +P + + ++DGA+A++++ E AL+ KP Y++ YVS+ Sbjct: 185 -PVISEP---LRLYEYTPISDGAAAVVMVRNEDALSYTSKP-VYIKGIGSSNYTAYVSEK 239 Query: 347 PKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRK 406 L A+ K +KA + ID E H+ IL ++ D F + + Sbjct: 240 EDFVTLPAVVEASRKAFKKA--KVERIDFAELHDM--ATILEIIQSEDIGLFKKGEGWKA 295 Query: 407 TKVGLPPLE---KFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGG-------QYGLVA 456 GL L+ N GG S GHP GA+G + A +++R E G + GL Sbjct: 296 VMEGLTSLDGEIPINPSGGLNSKGHPIGASGVAQAVEAFSQIRNEAGNRQVKNARVGLSL 355 Query: 457 ACAAGGQGHAMIV 469 + A G +I+ Sbjct: 356 SMAGYGNSATVII 368 >5M3K-C nrPDB Length = 398 Score = 100 bits (250), Expect = 9e-22, Method: Composition-based stats. Identities = 76/450 (16%), Positives = 139/450 (30%), Gaps = 91/450 (20%) Query: 52 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVK 111 R V +V TP G+S ++ + L + + + +G Sbjct: 4 RRVAIVSAAYTP--KPGSSRVRQTFKEMIVESAYKALKDAKMHPREIQAVAYGY-----H 56 Query: 112 TSNVAREAALGAGFSD-----KTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 ++ LG SD P T C S++ + G ++ASG+ D+++ GG E Sbjct: 57 GEGISEYGGLGPTISDALGISPAPTFMSTANCTSSSVSFQMGHQMVASGEYDIVLCGGFE 116 Query: 167 LMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHS 226 M+D N A+ +G + + A++ + Sbjct: 117 KMTD--------------HFNYAEYIGSSTECEYDYFLGISHTDAFALA----------T 152 Query: 227 ADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSL 286 A+ F + E D A + AQ+ P + ++ S Sbjct: 153 AEYF-QKFGYAGREADVLATFGRQMRIYAQN-------TPTATRYGQPIPSLEVLKNS-- 202 Query: 287 EQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQD 346 E + + +S +++AE A KP ++R Y Sbjct: 203 EACGSM----------LAWGEASG------CAILVAEHLAHKYTDKP-VFVRGCAYTGVS 245 Query: 347 -----------------PKDQLLLGPTYAT---PKVLEKAGLTMNDIDAFEFHEAFSGQI 386 PKD + + +KAG+T DID + ++ Sbjct: 246 HYFGTRFHNPTLHHPGLPKDVGMAVSANSIACAEIAYKKAGITAKDIDVAQVYDLLGA-G 304 Query: 387 LANFKAMDS-DWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRL 445 L ++M + + L N GG++ GH G G + +L Sbjct: 305 LIQMESMGICGKGQAGDFVLEGGIALDGQLPLNTDGGNIGRGHASGCDGILHITELFRQL 364 Query: 446 RKE------GGQYGLVAACAAGGQGHAMIV 469 R E G + G+ +++IV Sbjct: 365 RGESDNQVKGARIGVSQNLGGYAAHNSVIV 394 >4U4E-A nrPDB Length = 383 Score = 84.4 bits (207), Expect = 9e-17, Method: Composition-based stats. Identities = 58/392 (14%), Positives = 115/392 (29%), Gaps = 63/392 (16%) Query: 69 TSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDK 128 D L A L + VD ++ + + E + G + Sbjct: 20 GKVPDKPAIALHAEAALNALEEAGLTLRDVDGLLTAGISPLELGEYLGIEPSYTDGTAVG 79 Query: 129 TPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNK 188 + + + I +G+C V + I H R + Sbjct: 80 GSSFVIH---------LAHAAAAIVTGRCSVAL-----------ITHGESGRS---RVGM 116 Query: 189 AKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRS 248 + SL +F + P + S M A + ++ + E A+ + Sbjct: 117 PPRVPAPDSLRGQFEDPYGLPTPVGAYALACSRHM--------AEYGTTKEQLAEIAVAT 168 Query: 249 HSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPYGTVTAANS 308 + + D P ++E + +P + Sbjct: 169 -RKWAMLNPKAYMRD-------------------PITIEDVLNSRPIVWPFN----LLDC 204 Query: 309 SFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDP-----KDQLLLGPTYATPKVL 363 +TD A ++ + E+A + P A + + Sbjct: 205 CLVTDAGGACVVTSIERARDLRQHPVA-ILGVGESHDHSIISQMPSLTSFAARRSGQAAF 263 Query: 364 EKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLE-KFNNWGG 422 + AG+T +DID +++F+ +L + + + E + P + N GG Sbjct: 264 KMAGVTHDDIDLAMIYDSFTYTVLLSLEDLGFCAKGEGGAFVSGQRTAPGGDFPMNTNGG 323 Query: 423 SLSLGHPFGATGCRLVMAAANRLRKEGGQYGL 454 LS HP G G ++ A +LR + G+ Sbjct: 324 GLSYTHP-GMYGMFAIIEAVRQLRHDYADQGI 354 >4EWP-A nrPDB Length = 350 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 32/129 (24%), Positives = 50/129 (38%), Gaps = 1/129 (0%) Query: 61 RTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAA 120 RT + + + +A A L R + +D +I TV T + A A Sbjct: 47 RTGIVTRQRATAEETVPVMAVGAAREALERAGLQGSDLDAVIVSTVTFPHATPSAAALVA 106 Query: 121 LGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMR 180 G + PA+ V+ AC + L+ SG ++ GVE +SDV R + Sbjct: 107 HEIG-ATPAPAYDVSAACAGYCYGVAQADALVRSGTARHVLVVGVERLSDVVDPTDRSIS 165 Query: 181 KLMLDLNKA 189 L+ D A Sbjct: 166 FLLGDGAGA 174 >5AB6-A nrPDB Length = 425 Score = 53.2 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 68/439 (15%), Positives = 114/439 (25%), Gaps = 101/439 (23%) Query: 54 VVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS 113 V +V RT S +LA +AL L ++ + + +I + + Sbjct: 22 VRIVGVGRTGIGKLHKS-----VDELAASALKCALVDANMKQCDLQALIAVPSLASPQFM 76 Query: 114 NVAREAALGAGFSDKTP---AHTVTMACISANQAMTTGVGLIASGQCD---VIVAGGVEL 167 A A AG TV A+ V L+ + + VI A V Sbjct: 77 Q-AHHIATVAGLFPTKGKFIVRTVDTGGAGPITALGMAVDLVRTRCAETVAVIAADAVLS 135 Query: 168 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227 M S S R P +P + M Sbjct: 136 MGSGAFA--------------------ERSNASLRRSGLPEPCIPHGYDRYAQWYM---- 171 Query: 228 DRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLE 287 + + + R + + +A+ + + K D V + P + Sbjct: 172 ----SRYGLKREQLAMVPVLMSKMAE------RHPEAMCQKAYTLDEVLHSRCVAPVT-- 219 Query: 288 QMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAM------------GYKPKA 335 + DGA A+++ E G KP Sbjct: 220 ----------------NLLECARRADGAVALIVSGEAHYAEHFAQGKQEQRHLGGSKPI- 262 Query: 336 YLRDFMYVSQDPKDQLLLGP-----------TYATPKVLEKAGLTMNDIDAFEFHEAFSG 384 V++ G +A A L + DI F ++ F Sbjct: 263 ----IASVAEASGPLFPPGSSDDIVPDIFSCRHAARDAFLSANLNVGDIHFFGLYDCFPI 318 Query: 385 QILANFKAMDSDWFAEN---------YMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGC 435 ++ +A+ + M V P N GG G P+ Sbjct: 319 CLIQAVEAVGLCPEGKGGEFMETAYNEMLNNGGVLDPSKFPINTHGGLQCFGAPWEVPAM 378 Query: 436 RLVMAAANRLRKEGGQYGL 454 + A +L +E G L Sbjct: 379 YNITEAIAQLSEEAGDRQL 397 >4X0O-A nrPDB Length = 362 Score = 51.7 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 36/211 (17%), Positives = 60/211 (28%), Gaps = 32/211 (15%) Query: 61 RTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAA 120 RT S+ + DLA A + V E +D II T + N+A Sbjct: 39 RTGIEQRRISHVNTS--DLATVAAQHAIACAGVSVEEIDLIIVATCSPDSLIPNIASRVQ 96 Query: 121 LGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS----------D 170 G A + AC + T L+ + + G E +S Sbjct: 97 QNLGIP-SAAAFDLNAACTGFLYGLETATRLMQASHYRHALVIGAERLSFYLDWTKRDTA 155 Query: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSET-------- 222 V L K ++ ++ R P+ + ++ Sbjct: 156 VLFGDGAGAVVLSKTEQKVGLQDAQIGCDAQGRDILAVPKFGTAMDRFDADNGYWAFDFV 215 Query: 223 -----------MGHSADRLAAAFAVSRLEQD 242 MG +A ++ A +S E D Sbjct: 216 GKEIFKRAVRGMGAAAQQVLARSGLSTEEID 246 >5BY7-A nrPDB Length = 360 Score = 49.4 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 33/87 (37%), Gaps = 1/87 (1%) Query: 78 DLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMA 137 DLA A + L V E VD ++ GT + A A G D PA+ + Sbjct: 83 DLAHQAGSRALDAAGVTPEEVDLVVLGTATPDRLMPTTATVVADRLGI-DGVPAYQLQSG 141 Query: 138 CISANQAMTTGVGLIASGQCDVIVAGG 164 C A QA+ L+ G + G Sbjct: 142 CSGAVQALAVTRSLLLGGTARTALVLG 168 >4DFE-A nrPDB Length = 333 Score = 49.0 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 37/112 (33%) Query: 60 VRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREA 119 RT + D+ DLA A + + + +D II T + + A Sbjct: 49 ARTGIHARYFAEPDVTTSDLAFIASQRAIEAADIDPQSIDLIIVATSTPDFVFPSTACLL 108 Query: 120 ALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDV 171 G + A V C A+ T I SGQ + G E S + Sbjct: 109 QNKLGIRNHGAAFDVQAVCSGFAYAVATADSFIRSGQHRTALVIGAETFSRI 160 >4YUC-A nrPDB Length = 335 Score = 48.6 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 30/85 (35%), Gaps = 3/85 (3%) Query: 68 GTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYII--FGTVIQEVKTSNVAREAALGAGF 125 KD + A + + E +D II G+ Q V + LG G Sbjct: 50 RRWVKDETASFMGAEAAKEAVRDAGLKLEDIDLIINASGSPEQAVPDGGPLVQRELGLGR 109 Query: 126 SDKTPAHTVTMACISANQAMTTGVG 150 S P+ TV +C+S A+ Sbjct: 110 S-GVPSITVNASCLSFFVALDVAAN 133 Score = 31.6 bits (70), Expect = 0.83, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 25/65 (38%), Gaps = 8/65 (12%) Query: 317 AMLIMAEEKALAMGYKP-----KAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMN 371 A ++++ + P K +R+ +V + + A + + AGL + Sbjct: 22 ADVVLSSDLEKKYDLPPGWCVEKQGIRERRWVKDETASFMG---AEAAKEAVRDAGLKLE 78 Query: 372 DIDAF 376 DID Sbjct: 79 DIDLI 83 >1J3N-A nrPDB Length = 408 Score = 48.6 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 31/204 (15%), Positives = 53/204 (25%), Gaps = 33/204 (16%) Query: 82 AALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS--------------NVAR---------- 117 A L + E +D GT++ R Sbjct: 77 IAAQLALEDAGLKPEDLDPERVGTLVGTGIGGMETWEAQSRVFLERGPNRISPFFIPMMI 136 Query: 118 ------EAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDV 171 A+ GF P+ TV AC + A+ + + +I G+ D+++AGG E + Sbjct: 137 ANMASAHIAMRYGF--TGPSSTVVTACATGADALGSALRMIQLGEADLVLAGGTEA-AIT 193 Query: 172 PIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLA 231 P+ L + + + + A A Sbjct: 194 PMAIGAFAVMRALSTRNEEPEKASRPFTLSRDGFVMGEGAGVLVLEAYEHAKKRGARIYA 253 Query: 232 AAFAVSRLEQDEYALRSHSLAKKA 255 R + H K A Sbjct: 254 ELVGFGRSADAHHITEPHPEGKGA 277 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 28/168 (16%), Positives = 50/168 (29%), Gaps = 25/168 (14%) Query: 282 RPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFM 341 R E+ + +P + G V + +GA +++ A E A G + A L F Sbjct: 209 RNEEPEKAS--RPFTLSRDGFV-------MGEGAGVLVLEAYEHAKKRGARIYAELVGFG 259 Query: 342 YVS----QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDW 397 + G A + L+ AG+ + H + Sbjct: 260 RSADAHHITEPHPEGKGAALAMARALKDAGIAPEQVGYINAHGTSTPV------------ 307 Query: 398 FAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRL 445 + +V ++ +GH GA G +A L Sbjct: 308 GDRAEVLAIKRVFGDHAKRLMVSSTKSMIGHLLGAAGAVEAIATVQAL 355 >3O04-A nrPDB Length = 413 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 25/129 (19%), Positives = 40/129 (31%), Gaps = 18/129 (13%) Query: 311 LTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGP-----TYATPKVLEK 365 + +GA +++ E A A G K A + + D P A ++ Sbjct: 231 IGEGAGIVILEEYEHAKARGAKIYAEIVGYGATG-DAYHITAPAPNGEGAARAMKMAIDD 289 Query: 366 AGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLS 425 AGLT + +D H + + E V +K Sbjct: 290 AGLTPDKVDYINAH------------GTSTPYNDEYETQAIKTVFGEHAKKLAISSTKSM 337 Query: 426 LGHPFGATG 434 GH GA+G Sbjct: 338 TGHTLGASG 346 >3IL7-A nrPDB Length = 313 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 34/191 (17%), Positives = 58/191 (30%), Gaps = 22/191 (11%) Query: 73 DLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAA--LGAGFSDKTP 130 D DLA A + + E +D II T ++ VA LG G K Sbjct: 48 DQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTG---KVA 104 Query: 131 AHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAK 190 + AC +M T + SG I+ G + +S + R L D A Sbjct: 105 SMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAV 164 Query: 191 SMGQRLSLISKFRFNFLAPELPAVSEF-----------------STSETMGHSADRLAAA 233 +G+ + + + MG ++ R+ Sbjct: 165 IIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEK 224 Query: 234 FAVSRLEQDEY 244 ++ + D + Sbjct: 225 ANLTSDDIDLF 235 Score = 31.3 bits (69), Expect = 0.93, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 13/82 (15%) Query: 313 DGASAMLIMAEEKAL-----AMGY-----KPKAYLRDFMYVSQDPKDQLLLGPTY---AT 359 DGA A++I + MG K +D + + ++ A+ Sbjct: 159 DGAGAVIIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDAS 218 Query: 360 PKVLEKAGLTMNDIDAFEFHEA 381 +V+EKA LT +DID F H+A Sbjct: 219 TRVVEKANLTSDDIDLFIPHQA 240 >4QAV-A nrPDB Length = 415 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 29/72 (40%), Gaps = 4/72 (5%) Query: 311 LTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLL---GPTYATPKVLEKAG 367 + +GA +++ E A G K A + F S D GP A + L+ AG Sbjct: 233 IGEGAGILVLEELEHAKKRGAKIYAEIVGFGMSS-DAYHITAPNEEGPALAVTRALKDAG 291 Query: 368 LTMNDIDAFEFH 379 + D+D H Sbjct: 292 INPEDVDYVNAH 303 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 21/116 (18%), Positives = 31/116 (26%), Gaps = 29/116 (25%) Query: 80 ARAALTGLLHRTSVPK-EVVDYIIFGTVIQEVKTSNVAREAALGAGF--------SDKTP 130 AA + + + E +D G I + E A P Sbjct: 78 GIAAALQAIADSGLDDVENLDKDRIGVNIGSGIGGLPSIEVTGKAVIEGGARKINPFFIP 137 Query: 131 AHTVT--------------------MACISANQAMTTGVGLIASGQCDVIVAGGVE 166 + AC + A+ LI G D++VAGG E Sbjct: 138 GSLINLISGHVTILKGYRGPSYGMVSACTTGAHAIGNSARLIKYGDADIMVAGGAE 193 Score = 28.6 bits (62), Expect = 6.0, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 64 FLLSGTSYKDLMPHDLA-RAALTGLLHRTSVPKEVVDYI 101 F +S +Y P++ A+T L + E VDY+ Sbjct: 262 FGMSSDAYHITAPNEEGPALAVTRALKDAGINPEDVDYV 300 >3E60-A nrPDB Length = 424 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 16/38 (42%), Positives = 21/38 (55%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167 P H+V AC + A+ LIA G DV++AGG E Sbjct: 166 PNHSVVTACSTGAHAIGDAARLIALGDADVMLAGGTES 203 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 16/102 (15%), Positives = 38/102 (37%), Gaps = 13/102 (12%) Query: 282 RPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFM 341 R E+ + +P + G V + +GA+ +++ E A G + A + + Sbjct: 223 RNDDPERAS--RPYDVDRDGFV-------MGEGAAIVVLEELEHAKKRGARIYAEIIGYG 273 Query: 342 YVS----QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFH 379 + G + L++A + ++++D H Sbjct: 274 LSGDAYHITAPSESGEGAQRSMMAALKRAQVNVSELDYINAH 315 >3KZU-A nrPDB Length = 428 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 1/67 (1%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL-MSDVPIRHSRKMRKLMLDLNK 188 P H+V AC + A+ LIA G DV+VAGG E +S + + + L + N Sbjct: 170 PNHSVVTACATGTHAIGDAARLIAFGDADVMVAGGTESPVSRISLAGFAACKALSTERND 229 Query: 189 AKSMGQR 195 + R Sbjct: 230 DPTAASR 236 Score = 36.7 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 34/94 (36%), Gaps = 11/94 (11%) Query: 290 AKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS----Q 345 A +P G V + +GA +++ E ALA G K A + + Sbjct: 233 AASRPYDEDRDGFV-------MGEGAGIVVLEELEHALARGAKIYAEVIGYGMSGDAFHI 285 Query: 346 DPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFH 379 + G L++AG+ ++ID H Sbjct: 286 TAPTESGEGAQRCMVAALKRAGIVPDEIDYINAH 319 Score = 28.2 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 16/40 (40%), Gaps = 3/40 (7%) Query: 65 LLSGTSYKDLMPHDLARAALT---GLLHRTSVPKEVVDYI 101 +SG ++ P + A L R + + +DYI Sbjct: 277 GMSGDAFHITAPTESGEGAQRCMVAALKRAGIVPDEIDYI 316 >6QSP-A nrPDB Length = 406 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 113 SNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVP 172 + +R A + + PA T++ AC S+++A+ +G LI G D + GG + +S +P Sbjct: 151 GDPSRFLARY--LAIEGPAFTLSTACSSSSRAIISGQRLIEMGLVDAAIVGGADTLSRMP 208 Query: 173 IRHSRKMRKLMLDL 186 I + L L Sbjct: 209 INGFDSLESLSPTL 222 >4V2P-A nrPDB Length = 351 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 29/85 (34%), Gaps = 3/85 (3%) Query: 68 GTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYII--FGTVIQEVKTSNVAREAALGAGF 125 K + A + + +D II G+ Q V + LG G Sbjct: 66 RRWVKGETAAFMGAEAAKEAVRDAGLQLSDIDLIISASGSPQQAVPDGGPLVQRELGLGR 125 Query: 126 SDKTPAHTVTMACISANQAMTTGVG 150 S TPA TV +C+S A+ Sbjct: 126 S-GTPAITVNASCLSFFVALEVASN 149 >4NHD-A nrPDB Length = 319 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 27/135 (20%), Positives = 45/135 (33%), Gaps = 1/135 (0%) Query: 60 VRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREA 119 RT + + D+A A ++ + K +D II T + A + Sbjct: 38 ARTGIRERRIAADNETVADMAFFAAQNAINMAGIDKHDIDMIIVATTSASHTFPSAACQV 97 Query: 120 ALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKM 179 G PA + AC A++ + SG C ++ G + +S R Sbjct: 98 QGKLGI-KGCPAFDLAAACSGFMYALSIADQHVKSGMCKHVLVIGADALSKTCDPTDRST 156 Query: 180 RKLMLDLNKAKSMGQ 194 L D A +G Sbjct: 157 IILFGDGAGAVVVGA 171 >3H76-A nrPDB Length = 359 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 29/189 (15%), Positives = 53/189 (28%), Gaps = 8/189 (4%) Query: 36 PAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPK 95 P Q + + N + +V+ RT + L A + + Sbjct: 36 PKRQVSNHDLVGRINTSDEFIVE--RTGVRTRYHVEPEQAVSALMVPAARQAIEAAGLLP 93 Query: 96 EVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASG 155 E +D ++ T+ + + A G P + C + G I +G Sbjct: 94 EDIDLLLVNTLSPDHHDPSQACLIQPLLGL-RHIPVLDIRAQCSGLLYGLQMARGQILAG 152 Query: 156 QCD-VIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAV 214 V+V G E++S R R L + G + + + L Sbjct: 153 LARHVLVVCG-EVLSK---RMDCSDRGRNLSILLGDGAGAVVVSAGESLEDGLLDLRLGA 208 Query: 215 SEFSTSETM 223 M Sbjct: 209 DGNYFDLLM 217 Score = 34.3 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 15/35 (42%) Query: 345 QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFH 379 +P+ + A + +E AGL DID + Sbjct: 68 VEPEQAVSALMVPAARQAIEAAGLLPEDIDLLLVN 102 >5W2O-A nrPDB Length = 439 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 31/141 (21%), Positives = 44/141 (31%), Gaps = 25/141 (17%) Query: 313 DGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTY-------ATPKVLEK 365 + + MLI EE A A G KP A L ++ P A + LE Sbjct: 264 EAGALMLIETEEHAKARGAKPLARLLG---AGITSDAFHMVAPAADGVRAGRAMTRSLEL 320 Query: 366 AGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLS 425 AGL+ DID H + + ++ + + Sbjct: 321 AGLSPADIDHVNAH---------------GTATPIGDAAEANAIRVAGCDQAAVYAPKSA 365 Query: 426 LGHPFGATGCRLVMAAANRLR 446 LGH GA G + LR Sbjct: 366 LGHSIGAVGALESVLTVLTLR 386 Score = 41.7 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 25/72 (34%), Gaps = 6/72 (8%) Query: 95 KEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIAS 154 V + ++ + + + AG A C S ++A+ I Sbjct: 157 PRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVSA------CSSGSEAIAHAWRQIVM 210 Query: 155 GQCDVIVAGGVE 166 G DV V GGVE Sbjct: 211 GDADVAVCGGVE 222 >2EBD-A nrPDB Length = 309 Score = 45.1 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 65/199 (32%), Gaps = 12/199 (6%) Query: 60 VRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVA--R 117 RT K+ +A A L ++ E +D II T+ + + + A Sbjct: 35 TRTGI-KERRIAKEETITYMATQAAKEALREANLSPEELDLIILATLTPQKRFPSTACLV 93 Query: 118 EAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSR 177 +A L A A ++ AC A+ I SG+ ++ G E +S+ R Sbjct: 94 QAQLKA---KGVYAFDISAACSGFIYALDIADSFIKSGKAKNVLVIGAEKLSEAVDWEDR 150 Query: 178 KMRKLMLDLNKA----KSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAA 233 L D A +S + L ++ EL G ++A Sbjct: 151 STCVLFGDGAGAVVVTRSEDKSDILATRMYAEGSLEELLHADNCGYIRMKGRELFKVAVR 210 Query: 234 --FAVSRLEQDEYALRSHS 250 V R ++ ++ Sbjct: 211 SMEEVCREVLEKAGVKPEE 229 >3GWE-A nrPDB Length = 365 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 33/206 (16%), Positives = 56/206 (27%), Gaps = 27/206 (13%) Query: 43 KKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYII 102 +K LAK IR + T DLA A L + +V + VD++I Sbjct: 60 EKILAKTGIRERRIAAPRET-------------AADLAYEAARKLFAQGAVGADQVDFVI 106 Query: 103 F-----GTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQC 157 V+ R G A V + C ++ GL+ +G Sbjct: 107 LCTQAPDYVLPTSACMLQHR-----LGIPTHAGALDVNLGCSGYVYGLSLAKGLVETGAA 161 Query: 158 DVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEF 217 ++ + S H L + A + R Sbjct: 162 RCVLLLTADTYSK--YLHPLDKSVRTLFGDGASATAVIAEHGELERIGPFVFGTDGRGAP 219 Query: 218 STSETMGHSADRLAAAFAVSRLEQDE 243 + G + + +R +D Sbjct: 220 NLIVKAGLFRE--PKSADSAREHEDA 243 >2IX4-A nrPDB Length = 431 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 42/134 (31%), Gaps = 24/134 (17%) Query: 311 LTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS-----QDPKDQLLLGPTYATPKVLEK 365 + +G+ +++ E A G K A L + P + G A + L + Sbjct: 248 IGEGSGVIVLEEYEHAKRRGAKIYAELCGYGMSGDAHHITQPPED-GKGAVLAMTRALRQ 306 Query: 366 AGLTMNDIDAFEFHEAFS----GQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWG 421 +GL N ID H + K + S+ + + G Sbjct: 307 SGLCPNQIDYVNAHATSTPIGDAVEARAIKTVFSEHATSGTLAFSSTKG----------- 355 Query: 422 GSLSLGHPFGATGC 435 + GH GA G Sbjct: 356 ---ATGHLLGAAGA 366 Score = 41.7 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 20/52 (38%), Gaps = 6/52 (11%) Query: 118 EAALGAGF--SDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167 ++ GF + C + ++ +I G DV+VAGG E Sbjct: 161 HVSMKYGFQGPNHAAVTA----CATGAHSIGDATRMIQFGDADVMVAGGTES 208 >2GP6-A nrPDB Length = 434 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 41/130 (31%), Gaps = 24/130 (18%) Query: 313 DGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTY-------ATPKVLEK 365 +G + +LI EE A A G A + S ++ P A + ++ Sbjct: 258 EGGALLLIETEEHAKARGANILARIMGASITS---DGFHMVAPDPNGERAGHAITRAIQL 314 Query: 366 AGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLS 425 AGL DID H + + N +G P + Sbjct: 315 AGLAPGDIDHVNAHATGTQVG-----DLAEGRAINNALGGNRPAVYAPKS---------A 360 Query: 426 LGHPFGATGC 435 LGH GA G Sbjct: 361 LGHSVGAVGA 370 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 3/105 (2%) Query: 119 AALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL-MSDVPIRHSR 177 AA+G K T AC S +A+ I G+ D + GGVE + VPI Sbjct: 168 AAVGLERHAKAGVMTPVSACASGAEAIARAWQQIVLGEADAAICGGVETRIEAVPIAGFA 227 Query: 178 KMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSET 222 +MR +M N + R + R F+ E A+ T E Sbjct: 228 QMRIVMSTNNDDPAGACR--PFDRDRDGFVFGEGGALLLIETEEH 270 >1OXH-A nrPDB Length = 430 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 37/245 (15%), Positives = 70/245 (28%), Gaps = 21/245 (8%) Query: 131 AHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLN-KA 189 ++ AC S+N A+ I G DV++ GG E S P + L Sbjct: 176 CKSINTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEA-SITPFAIAGFQALTALSTTEDP 234 Query: 190 KSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRS- 248 + + +E G + + + D Y + S Sbjct: 235 TRASIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNT---CDAYHMTSP 291 Query: 249 HSLAKKAQDEGLL----SDVVP-----FKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKP 299 H + A L +++ P G T + G + + + K P Sbjct: 292 HPEGQGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPV---- 347 Query: 300 YGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYAT 359 + T + + L A A+ + +A+ + P + + G Sbjct: 348 --SSTKSFTGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEI 405 Query: 360 PKVLE 364 P + Sbjct: 406 PYAIS 410 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 28/193 (14%), Positives = 51/193 (26%), Gaps = 30/193 (15%) Query: 258 EGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASA 317 G + + PF + G +T S+ E + F K +G+ Sbjct: 208 GGTEASITPFAIAGFQALTA-----LSTTEDPTRASIPFDKDRNGFVMG------EGSGM 256 Query: 318 MLIMAEEKALAMGYKPKAYLRDFMYV----SQDPKDQLLLGPTYATPKVLEKAGLTMNDI 373 +++ + E A G A + + G A LE+A ++ + Sbjct: 257 LVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEGQGAIKAIKLALEEAEISPEQV 316 Query: 374 DAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGAT 433 H N G + ++ GH GA Sbjct: 317 AYVNAH---------------GTSTPANEKGESGAIVAVLGKEVPVSSTKSFTGHLLGAA 361 Query: 434 GCRLVMAAANRLR 446 G + +R Sbjct: 362 GAVEAIVTIEAMR 374 >1MZJ-A nrPDB Length = 339 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 31/137 (22%), Positives = 48/137 (35%), Gaps = 5/137 (3%) Query: 60 VRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS--NVAR 117 RT + D + AA L V +D ++ T+ V T +VA Sbjct: 44 TRTGIRSRRIAEPDETIQVMGVAASRRALEHAGVDPAEIDLVVVSTMTNFVHTPPLSVAI 103 Query: 118 EAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSR 177 LGA D ++ AC A++ + SG ++ E M+DV R Sbjct: 104 AHELGA---DNAGGFDLSAACAGFCHALSIAADAVESGGSRHVLVVATERMTDVIDLADR 160 Query: 178 KMRKLMLDLNKAKSMGQ 194 + L D A +G Sbjct: 161 SLSFLFGDGAGAAVVGP 177 Score = 29.3 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 16/31 (51%) Query: 346 DPKDQLLLGPTYATPKVLEKAGLTMNDIDAF 376 +P + + + A+ + LE AG+ +ID Sbjct: 55 EPDETIQVMGVAASRRALEHAGVDPAEIDLV 85 >4RYB-A nrPDB Length = 320 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 30/80 (37%) Query: 92 SVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGL 151 + +D II T +++ + A G ++ PA V C A+TT Sbjct: 68 GLDSGEIDLIIVATATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANAY 127 Query: 152 IASGQCDVIVAGGVELMSDV 171 I SG + G E S + Sbjct: 128 IKSGMAKNALVIGAETFSRI 147 >4JPF-A nrPDB Length = 436 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 46/158 (29%), Gaps = 33/158 (20%) Query: 287 EQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS-- 344 E +P G V L+DG+ A+++ E A A G + A L F Sbjct: 237 EPTRASRPWDRDRDGFV-------LSDGSGALVLEELEHARARGARIYAELVGFGMSGDA 289 Query: 345 ---QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFH----EAFSGQILANFKAMDSDW 397 P + G L AGL +D H A +A K++ + Sbjct: 290 FHMTAPPED-GAGAARCMKNALRDAGLDPRQVDYINAHGTSTPAGDIAEIAAVKSVFGEH 348 Query: 398 FAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGC 435 M + GH GA G Sbjct: 349 AHALSMSSTKSMT----------------GHLLGAAGA 370 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 28/66 (42%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKA 189 P + +T AC + ++ IA G+ DV+VAGG E+ + + + N Sbjct: 178 PNYALTTACTTGTHSIGMAARNIAYGEADVMVAGGSEMAACGLGLGGFGAARALSTRNDE 237 Query: 190 KSMGQR 195 + R Sbjct: 238 PTRASR 243 >4DDO-A nrPDB Length = 451 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 24/155 (15%), Positives = 45/155 (29%), Gaps = 28/155 (18%) Query: 287 EQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQD 346 E + +P G V + +GA+ +++ + + ALA G +P A + + + Sbjct: 245 EPVRASRPFDRDRDGFV-------MGEGAAMVVVESLDHALARGARPIAEIIGYGTTAD- 296 Query: 347 PKDQLLLGP------TYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAE 400 + GP A L + +D H A + + Sbjct: 297 -AYHMTAGPDDGSGAMRAMKLALRMGDVAPEQVDYVNAH----ATSTPVGDAGEIEALKT 351 Query: 401 NYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGC 435 + + GH GA G Sbjct: 352 VFGVGAGPAISSTKS---------ATGHLLGAAGA 377 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 21/31 (67%) Query: 137 ACISANQAMTTGVGLIASGQCDVIVAGGVEL 167 AC ++ QA+ + +I +G+ DV++AGG E Sbjct: 192 ACAASVQAIGDAMRMIRTGEADVVLAGGAEA 222 >5BQS-A nrPDB Length = 323 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 62/273 (22%), Positives = 101/273 (36%), Gaps = 41/273 (15%) Query: 78 DLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAR--EAALGAGFSDKTPAHTVT 135 DLA L+ + + + +D+II T+ + + A +A +GA +K A +T Sbjct: 52 DLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGA---NKAFAFDLT 108 Query: 136 MACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQR 195 AC A++T IASG+ + G E +S R L D + G Sbjct: 109 AACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGD----GAGGVL 164 Query: 196 LSLISKFRFNFLAPELPAV-SEFSTSETMGHSADRLAAAFAVSRLEQD-----EYALRSH 249 L + F + SE T G + A S L+ D ++A+R Sbjct: 165 LEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVFDFAIRDV 224 Query: 250 SLAKKAQDEGLLSDVVPFKVPGKDTVT--------KDNGIRPSSLEQMAKLKPAFIKPYG 301 + + K D P +V D + D R +++ AKL PA + YG Sbjct: 225 AKSIKQTI-----DESPIEVTDLDYLLLHQANDRILDKMARKIGVDR-AKL-PANMMEYG 277 Query: 302 TVTAANSSFLTDGASAMLIMAEEKALAMGYKPK 334 +A AS ++++E G P Sbjct: 278 NTSA---------ASIPILLSECV--EQGLIPL 299 >4R8E-A nrPDB Length = 413 Score = 41.7 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 35/129 (27%), Gaps = 16/129 (12%) Query: 311 LTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS----QDPKDQLLLGPTYATPKVLEKA 366 L DGA M++ E A G K A + F S + G A L A Sbjct: 232 LGDGAGMMVLEEYEHAKKRGAKIYAEVVGFGMSSDAYHMTSPPEDGSGAALAMVNALRDA 291 Query: 367 GLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSL 426 G+T + I H + + V K Sbjct: 292 GITTSQIGYINAH------------GTSTPAGDKAETQAVKSVFGEDAYKVMVSSTKSMT 339 Query: 427 GHPFGATGC 435 GH GA G Sbjct: 340 GHLLGAAGA 348 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 23/62 (37%), Gaps = 1/62 (1%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKA 189 P+ ++ AC S + +IA DV+VAGG E S P+ L Sbjct: 156 PSISIATACTSGVHNIGHAARIIAYNDADVMVAGGAEKAST-PLGVGGFGAARALSTRND 214 Query: 190 KS 191 Sbjct: 215 NP 216 >4JRH-A nrPDB Length = 417 Score = 41.7 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 23/140 (16%), Positives = 36/140 (25%), Gaps = 29/140 (20%) Query: 80 ARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS----NVAREAALGAG----FSDKTPA 131 AA L + + + G I +A + G P+ Sbjct: 81 GIAAGIQALEDSGLEVNEENAARIGVAIGSGIGGLELIETGHQALIEKGPRKVSPFFVPS 140 Query: 132 HTVTMA--------------------CISANQAMTTGVGLIASGQCDVIVAGGVELMSDV 171 V M C + + +IA G D +VAGG E S Sbjct: 141 TIVNMIAGNLSIMRGLRGPNIAISTACTTGLHNIGHAARMIAYGDADAMVAGGAEKAST- 199 Query: 172 PIRHSRKMRKLMLDLNKAKS 191 P+ + L + Sbjct: 200 PLGMAGFGAAKALSTRNDEP 219 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 29/143 (20%), Positives = 43/143 (30%), Gaps = 19/143 (13%) Query: 311 LTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS----QDPKDQLLLGPTYATPKVLEKA 366 L DGA M++ E A A G K A + F + G A + A Sbjct: 235 LGDGAGIMVLEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDA 294 Query: 367 GLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSL 426 G+T I H + G K +G ++ Sbjct: 295 GVTGEQIGYVNAHGTSTPAG-----------DVAEVKGIKRALGEAGTKQVLVSSTKSMT 343 Query: 427 GHPFGATGCRL----VMAAANRL 445 GH GA G VM+ +++ Sbjct: 344 GHLLGAAGSVEAIITVMSLVDQM 366 >4JGA-A nrPDB Length = 437 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 23/58 (39%), Gaps = 5/58 (8%) Query: 115 VAREAALGAGFSD-----KTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167 A L +G P T AC + A+ + +I G DV++AGG E Sbjct: 157 PASLINLLSGLVSIKYGFSGPNQTAVTACSTGAHAIGDAMRMIKHGYADVMIAGGAEA 214 Score = 37.8 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 36/127 (28%), Gaps = 16/127 (12%) Query: 313 DGASAMLIMAEEKALAMGYKPKAYLRDFMYVS----QDPKDQLLLGPTYATPKVLEKAGL 368 +GA +++ E AL G K + + G A + A + Sbjct: 256 EGAGVVVLEEYEHALNRGAKVYGEVIGYGSTGDAYHMTAPHPEGRGAYRAMRDAMLDATI 315 Query: 369 TMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGH 428 T + ID H + + K+ L K S+GH Sbjct: 316 TPDMIDYINAH------------GTSTTLGDGIELAAVQKLFLEANPKVLMSSTKSSIGH 363 Query: 429 PFGATGC 435 GA G Sbjct: 364 LLGAAGS 370 >5ENY-A nrPDB Length = 764 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 21/170 (12%), Positives = 48/170 (28%), Gaps = 16/170 (9%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE---------LMSDVPIRHSRKMR 180 PA + AC S+ + + + D+ + GGV M + + Sbjct: 334 PAIPIDTACSSSLVGTHLARQALINKEIDMALVGGVSLYLTPESYMSMCEAGMLSPDGQC 393 Query: 181 KLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETM-------GHSADRLAAA 233 K + G+ + R + + + G +A + Sbjct: 394 KAFDNGANGFVPGEGAGALVLKRLKDAEADRDHIYGIIIGSGINQDGKTNGITAPSAKSQ 453 Query: 234 FAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRP 283 + R + Y + S++ P ++ TV ++ + Sbjct: 454 MDLERDIYETYGIHPESISYVEMHGTGTKQGDPIELEALSTVFQEKTDKK 503 >3IL4-A nrPDB Length = 320 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 1/93 (1%) Query: 78 DLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMA 137 DL LL ++ +D+I+ TV + +VA + G ++ A ++ A Sbjct: 53 DLCHQVAKQLLEKSGKQASEIDFILVATVTPDFNMPSVACQVQGAIGATEAF-AFDISAA 111 Query: 138 CISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170 C A++ L+ SG+ + G E S Sbjct: 112 CSGFVYALSMAEKLVLSGRYQTGLVIGGETFSK 144 >4LS7-A nrPDB Length = 426 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 35/100 (35%), Gaps = 11/100 (11%) Query: 284 SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYV 343 ++ + +P G V + +GA +++ E ALA G K + + Sbjct: 224 TNPDPKTASRPFDKNRDGFV-------MGEGAGIIVLEELEHALARGAKIYGEIVGYGST 276 Query: 344 S----QDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFH 379 Q G A + ++ AG+ +ID H Sbjct: 277 GDAYHITAPAQDGEGGARAMQEAIKDAGIAPEEIDYINAH 316 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 30/176 (17%), Positives = 55/176 (31%), Gaps = 21/176 (11%) Query: 118 EAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL----MSDVPI 173 + ++ G + + TVT AC + ++ +I G DV+V GG E MS Sbjct: 159 QISIALG-AKGVNSCTVT-ACATGTNSIGDAFKVIQRGDADVMVTGGTEAPLTRMSFAGF 216 Query: 174 RHSRKMRKLMLDLNKAKSMGQRL-------SLISKFRFNFLAPELPAVSEFSTSETMGHS 226 ++ + ++ + + G + Sbjct: 217 SANKALSTNPDPKTASRPFDKNRDGFVMGEGAGIIVLEELEHALARGAKIYGEIVGYGST 276 Query: 227 ADRLAAAFAVSRLEQD-EYALRSHSLAKKAQDEGLL-SDVVPFKVPGKDTVTKDNG 280 D A+ ++ QD E R+ A K D G+ ++ G T D Sbjct: 277 GD----AYHITAPAQDGEGGARAMQEAIK--DAGIAPEEIDYINAHGTSTYYNDKY 326 Score = 31.3 bits (69), Expect = 0.95, Method: Composition-based stats. Identities = 8/40 (20%), Positives = 15/40 (37%), Gaps = 3/40 (7%) Query: 65 LLSGTSYKDLMPH---DLARAALTGLLHRTSVPKEVVDYI 101 +G +Y P + A+ + + E +DYI Sbjct: 274 GSTGDAYHITAPAQDGEGGARAMQEAIKDAGIAPEEIDYI 313 >2AJ9-A nrPDB Length = 356 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 23/139 (16%), Positives = 42/139 (30%), Gaps = 7/139 (5%) Query: 59 GVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIF---GTVIQEVKTSNV 115 RT + D +A A L + +D +I +Q + Sbjct: 65 YTRTGIKTRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPAA-P 123 Query: 116 AREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRH 175 A+LGA ++ C A+ +I G ++ G E +S + Sbjct: 124 MVAASLGA---KGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLSPTIDMY 180 Query: 176 SRKMRKLMLDLNKAKSMGQ 194 + D A +G+ Sbjct: 181 DAGNCFIFADGAAAVVVGE 199 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 41/114 (35%), Gaps = 23/114 (20%) Query: 305 AANSSFLTDGASAMLIMA-------EEKALAMGYKPKAYL--RDFMYVSQDP----KDQL 351 A N DGA+A+++ A + G + A D++ +Q+P Sbjct: 182 AGNCFIFADGAAAVVVGETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFVR 241 Query: 352 LLGPTY----------ATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDS 395 L GP + ++ AG+ + ID F H+A S K + Sbjct: 242 LEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINELLVKNLQL 295 >2IWZ-A nrPDB Length = 438 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 37/200 (18%), Positives = 59/200 (29%), Gaps = 31/200 (15%) Query: 242 DEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKL--KPAFIKP 299 D + +H A G S + P + G R S KL +P K Sbjct: 197 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFS------RARALSTNSDPKLACRPFHPKR 250 Query: 300 YGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVS----QDPKDQLLLGP 355 G V + +GA+ +++ E A+ + A + + D G Sbjct: 251 DGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGA 303 Query: 356 TYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLE 415 L+ AG+ +I H A + D + K L Sbjct: 304 LRCMAAALKDAGVQPEEISYINAH--------ATSTPLG-DAAENKAIKHLFKDHAYALA 354 Query: 416 KFNNWGGSLSLGHPFGATGC 435 + G + GH GA G Sbjct: 355 VSSTKG---ATGHLLGAAGA 371 Score = 37.0 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 20/38 (52%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167 P H V+ AC + A+ IA G DV+VAGG + Sbjct: 180 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 217 >5YO9-A nrPDB Length = 371 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 30/85 (35%), Gaps = 2/85 (2%) Query: 78 DLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMA 137 + A + V E +D +I ++ + A + + + A+ + +A Sbjct: 100 EWGVIAAKQAMENAGVTAEDIDVVILAC--SNMQRAYPAVAIEIQSALGIQGYAYDMNVA 157 Query: 138 CISANQAMTTGVGLIASGQCDVIVA 162 +A + I SG V++ Sbjct: 158 ASAATFGLKQAADAIRSGARRVLLV 182 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 16/45 (35%), Gaps = 5/45 (11%) Query: 356 TYATPKVLEKAGLTMNDIDAF-----EFHEAFSGQILANFKAMDS 395 A + +E AG+T DID A+ + A+ Sbjct: 103 VIAAKQAMENAGVTAEDIDVVILACSNMQRAYPAVAIEIQSALGI 147 >6ESQ-I nrPDB Length = 349 Score = 38.2 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 36/106 (33%), Gaps = 5/106 (4%) Query: 72 KDLMPHD-----LARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFS 126 K + D +A A + R + E + + G+ + A G + Sbjct: 43 KSVPSPDEDTATIAVEAARNAVKRAGINAEKIGAVYVGSESHPYAVKPTSATVAEAIGAT 102 Query: 127 DKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVP 172 A + AC + + +GL+ SG + +A G + P Sbjct: 103 PDLTAADLEFACKAGTAGIQMCMGLVGSGLIEYGMAIGADTAQGAP 148 >3HO9-A nrPDB Length = 427 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 25/81 (30%), Gaps = 1/81 (1%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKA 189 P+ ++ A S + +IA G DV+VAGG E S P+ L Sbjct: 170 PSISIATAATSGVHNIGHAARIIAYGDADVMVAGGAEKAST-PLGVGGFGAARALSTRND 228 Query: 190 KSMGQRLSLISKFRFNFLAPE 210 + L Sbjct: 229 NPQAASRPWDKERDGFVLGDG 249 >4EFI-A nrPDB Length = 354 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 30/117 (25%), Positives = 44/117 (37%), Gaps = 9/117 (7%) Query: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 +R+VV + GV + DL R A LL + +D +IF V Q Sbjct: 45 VRDVVKMIGV----NRRRWADAQTSAGDLCRKAGEKLLAGLGWQADSIDALIF--VSQTP 98 Query: 111 KTSNVAREAALGAGF--SDKTPAHTVTMACISANQAMTTGVGLIASGQCD-VIVAGG 164 A L A A + + C QA+ G+ LI +G V++A G Sbjct: 99 NYRLPATAFVLQAELDLPASCLALDINLGCSGYPQALWLGMNLIQTGAAKRVLLAVG 155 >4OQJ-A nrPDB Length = 845 Score = 36.7 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 40/130 (30%), Gaps = 17/130 (13%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGV-------------ELMSDVPIRHS 176 P+ + AC ++ A+ + SG C + +AG E M P H Sbjct: 185 PSVSTNTACSTSLVAVHLACLSLLSGDCTMALAGAAHIQADQGEGYLHHEGMIFSPDGHC 244 Query: 177 RKMRKLMLDLNKAKSMG----QRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAA 232 R +G +RLS A S+ G++A + Sbjct: 245 RAFDAKAQGTVIGNGVGAVVLKRLSDALADGDTVHAVIKGTAVNNDGSDKTGYTAPSVQG 304 Query: 233 AFAVSRLEQD 242 AV Q+ Sbjct: 305 QAAVVAEAQE 314 >4JD3-A nrPDB Length = 353 Score = 35.9 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 29/96 (30%), Gaps = 7/96 (7%) Query: 62 TPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAAL 121 T F + + + DL AL G L ++ +D I TV S AR A Sbjct: 63 TDFGDANEIFIE-KAVDLGVEALLGALDDANLRPSDIDMIATATVTGVAVPSLDARIAGR 121 Query: 122 GAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQC 157 D V + ++ G+ Sbjct: 122 LGLRPD------VRRMPLFGLGSVAGAAGVARLRDY 151 >4XOX-A nrPDB Length = 404 Score = 35.9 bits (81), Expect = 0.044, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 36/111 (32%), Gaps = 28/111 (25%) Query: 84 LTGLLHRTSVPKEVVDY----IIFGTVIQEVKTSNVA----REAALGAGFSDKTPAH--- 132 L + + E V I+ G+ + +A RE + P Sbjct: 79 LEQAIADAGLTPEQVSNDRTGIVAGSGGASSENQVIAVDTQREKGVKRVGPYMVPRTMSS 138 Query: 133 -----------------TVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 +++ AC ++ + V LI G+ D++ AGG E Sbjct: 139 TVSACLATPFKIRGVNYSISSACATSAHCIGNAVELIQLGKQDIVFAGGGE 189 >1PV9-A nrPDB Length = 348 Score = 35.1 bits (79), Expect = 0.066, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 44/131 (33%), Gaps = 13/131 (9%) Query: 134 VTMACISANQAMTTGVGLIASGQCDVIVAGGVE---LMSDV--PIRHSRKMRKLMLDLNK 188 + AC A++A+ + I G+ + VA VE M+ P + L Sbjct: 133 IEKACEIADKAVMAAIEEITEGKREREVAAKVEYLMKMNGAEKPAFDTIIASGHRSALPH 192 Query: 189 AKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRS 248 + +R+ + A S+ + + +G ++ + + L + Sbjct: 193 GVASDKRIERGDLVVIDLGALYNHYNSDITRTIVVGSPNEKQREIYEI--------VLEA 244 Query: 249 HSLAKKAQDEG 259 A +A G Sbjct: 245 QKRAVEAAKPG 255 >4YLT-A nrPDB Length = 316 Score = 35.1 bits (79), Expect = 0.067, Method: Composition-based stats. Identities = 28/158 (17%), Positives = 50/158 (31%), Gaps = 4/158 (2%) Query: 38 VQTKTKKTLAK-PNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKE 96 VQ ++ L K + + +V RT + D + A L + K+ Sbjct: 14 VQVRSNADLEKMVDTSDEWIV--TRTGIRERRIAGLDETVATMGFQAAEKALEMAGIDKD 71 Query: 97 VVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQ 156 + II T + A + G + + AC A++ + SG Sbjct: 72 DIGLIIVATTSSSHAFPSSACQVQRMLGI-KDAASFDLAAACAGFTYALSVADQYVKSGA 130 Query: 157 CDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQ 194 + G +++S R L D A +G Sbjct: 131 VKHAIVIGSDVLSRALDPEDRGTIILFGDGAGAVVLGA 168 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 16/52 (30%), Gaps = 5/52 (9%) Query: 357 YATPKVLEKAGLTMNDIDAFEF-----HEAFSGQILANFKAMDSDWFAENYM 403 A K LE AG+ +DI AF + + A + Sbjct: 57 QAAEKALEMAGIDKDDIGLIIVATTSSSHAFPSSACQVQRMLGIKDAASFDL 108 >1WY2-A nrPDB Length = 351 Score = 34.7 bits (78), Expect = 0.088, Method: Composition-based stats. Identities = 20/120 (16%), Positives = 43/120 (35%), Gaps = 6/120 (5%) Query: 134 VTMACISANQAMTTGVGLIASGQCDVIVAGGVE---LMSDV--PIRHSRKMRKLMLDLNK 188 + AC A++A+ + I G+ + VA VE M+ P + L Sbjct: 136 IEKACEIADKAVMAAIEEITEGKKEREVAAKVEYLMKMNGAEKPAFDTIIASGYRSALPH 195 Query: 189 AKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRS 248 + +R+ + A S+ + + +G ++ + + Q + A+ S Sbjct: 196 GVASDKRIERGDLVVIDLGALYQHYNSDITRTIVVGSPNEKQKEIYEIVLEAQKK-AVES 254 >5BNS-A nrPDB Length = 317 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 18/105 (17%), Positives = 32/105 (30%), Gaps = 1/105 (0%) Query: 60 VRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREA 119 RT + + + A T + + K+ + I+ T + A + Sbjct: 35 TRTGIRERHIAAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQI 94 Query: 120 ALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGG 164 G PA V AC A++ + SG + G Sbjct: 95 QSMLGI-KGCPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVG 138 >2BZ4-A nrPDB Length = 418 Score = 34.3 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 23/48 (47%) Query: 119 AALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 A L F ++++ AC ++ + V I G+ D++ AGG E Sbjct: 156 ACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGE 203 >2P1R-A nrPDB Length = 299 Score = 34.0 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 49/136 (36%), Gaps = 23/136 (16%) Query: 258 EGLLSDVVPFKVPGKDTVTKDNGIR---PSSLEQMAKLKPAFIKPY---GTVTAANSSF- 310 G +D P + T+ +D GI+ + E+ + TV A Sbjct: 12 NGKSADNQPLR--EAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVETVIAGGGDGT 69 Query: 311 LTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEK--AGL 368 + + ++A++ + + A A+G P DF + P A K L+ AG Sbjct: 70 INEVSTALIQIRDGVAPALGLLPLGTANDFATSAGIP---------EALDKALKLAIAGN 120 Query: 369 TMNDIDAFEFHE--AF 382 M ID ++ F Sbjct: 121 AME-IDMAMVNDKTCF 135 >1TQY-B nrPDB Length = 415 Score = 34.0 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 19/83 (22%), Gaps = 4/83 (4%) Query: 77 HDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAAL---GAGFSDKTPAHT 133 A+ L+ E VD + + AR G P T Sbjct: 278 PAGLERAIRLALNDAGTGPEDVDVVFADGAGVPELDAAEARAIGRVFGREGVPVTVPKTT 337 Query: 134 VTMA-CISANQAMTTGVGLIASG 155 + T + + G Sbjct: 338 TGRLYSGGGPLDVVTALMSLREG 360 >1TQY-A nrPDB Length = 424 Score = 34.0 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 15/34 (44%) Query: 130 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAG 163 P V+ C S ++ V I G DV+ AG Sbjct: 161 PVTMVSTGCTSGLDSVGNAVRAIEEGSADVMFAG 194 >3OA3-A nrPDB Length = 288 Score = 34.0 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 40/115 (34%), Gaps = 19/115 (16%) Query: 66 LSGTSYKDLMPHDLAR--AALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVARE----- 118 ++D+ LA A L +L + + D II G V+ + ++ + Sbjct: 156 RYTDVFQDIRAVRLAAKDAILKVILETSQLTA---DEIIAGCVLSSLAGADYVKTSTGFN 212 Query: 119 --------AALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGV 165 +L + D + T A + + V ++ +G + + GV Sbjct: 213 GPGASIENVSLMSAVCDSLQSETRVKASG-GIRTIEDCVKMVRAGAERLGASAGV 266 >1UB7-A nrPDB Length = 322 Score = 34.0 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 34/161 (21%), Positives = 60/161 (37%), Gaps = 3/161 (1%) Query: 60 VRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREA 119 RT + +D DLA A+ LL R E VD +I T + + A A Sbjct: 34 TRTGIKERRVAAEDEYTSDLAFKAVEDLLRRHPGALEGVDAVIVATNTPDALFPDTA--A 91 Query: 120 ALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKM 179 + A F K A+ + C A+ L+ +G ++A G E +S + I + + Sbjct: 92 LVQARFGLKAFAYDLLAGCPGWIYALAQAHALVEAGLAQKVLAVGAEALSKI-IDWNDRA 150 Query: 180 RKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTS 220 ++ ++ ++ FR L + E + Sbjct: 151 TAVLFGDGGGAAVVGKVREGYGFRSFVLGADGTGAKELYHA 191 Score = 30.1 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 16/40 (40%), Positives = 21/40 (52%) Query: 358 ATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDW 397 AT + +EKAGLT DI F H+A I A + + W Sbjct: 225 ATLEAIEKAGLTPEDIRLFVPHQANLRIIDAARERLGLPW 264 >1E5M-A nrPDB Length = 416 Score = 33.6 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 25/72 (34%), Gaps = 5/72 (6%) Query: 121 LGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMR 180 LGA + C + + A+ L+ +G ++ GG E + P+ ++ Sbjct: 154 LGAKGPNNCTVTA----CAAGSNAIGDAFRLVQNGYAKAMICGGTEA-AITPLSYAGFAS 208 Query: 181 KLMLDLNKAKSM 192 L + Sbjct: 209 ARALSFRNDDPL 220 >6ET0-A nrPDB Length = 365 Score = 33.2 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 30/81 (37%), Gaps = 4/81 (4%) Query: 332 KPKAYLRDFMYVSQDPKDQLLLGPTY-ATPKVLEKAGLTMNDIDAFEFHEAFSGQILANF 390 KP+ Y F Q+ + A + LEKAGL +DID F FH+ L Sbjct: 239 KPRLYFSLFSD-GQNKMASFVPTNVPIAMRRALEKAGLGSDDIDYFVFHQ--PAPFLVKA 295 Query: 391 KAMDSDWFAENYMGRKTKVGL 411 A E Y G+ Sbjct: 296 WAEGIGARPEQYQLTMGDTGV 316 >2GQD-A nrPDB Length = 437 Score = 32.0 bits (71), Expect = 0.52, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 22/64 (34%), Gaps = 8/64 (12%) Query: 121 LGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE----LMSDVPIRHS 176 LGA + C + ++ ++ G D ++ GG E M+ S Sbjct: 175 LGAKGPNGATVTA----CATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSAS 230 Query: 177 RKMR 180 R + Sbjct: 231 RALS 234 >2OEL-A nrPDB Length = 413 Score = 31.6 bits (70), Expect = 0.68, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 31/108 (28%), Gaps = 23/108 (21%) Query: 344 SQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYM 403 + P + + P+ K+L AG D F + L +A+ + Sbjct: 270 AVTPSEFYGVAPSLWLGKLLRLAG-----ADFVLFPSPYGSVALEREQALGIARALTDDQ 324 Query: 404 GRKTKVGLPPLEKFNNW-----------------GGSLSLGHPFGATG 434 + P + GG + GHP GA G Sbjct: 325 EPFARAFPVPSAGIHPGLVPLIIRDFGLDTIVNAGGGIH-GHPDGAIG 371 >3OYT-A nrPDB Length = 410 Score = 31.6 bits (70), Expect = 0.74, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 25/48 (52%) Query: 119 AALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 A L F K ++++ AC ++ + + LI G+ D++ AGG E Sbjct: 148 ACLATPFKIKGVNYSISSACATSAHCIGHALELIQLGKQDIVFAGGGE 195 >4COG-A nrPDB Length = 215 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 26/61 (42%) Query: 314 GASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDI 373 GA+ ++ A+ +A G P+ LR + + + D T +L G+ + I Sbjct: 87 GAAPVVRPADVEAALDGVPPRVLLRTYARAAVEQWDSNFCAVAPDTVDLLAAHGVKLIGI 146 Query: 374 D 374 D Sbjct: 147 D 147 >3VEW-A nrPDB Length = 576 Score = 30.9 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 353 LGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAE 400 P A L +AGLT++D+DA AF + A ++ W Sbjct: 50 TAPVQAAAFCLAQAGLTVDDLDAV----AFGWDLPAMYRERLGGWPHS 93 >5N6R-A nrPDB Length = 218 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 38/93 (40%) Query: 172 PIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLA 231 P++ + + +L + +++ ++ + + F P V ++S + +G +LA Sbjct: 42 PLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLA 101 Query: 232 AAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDV 264 + V R D Y + K Q +++ Sbjct: 102 SQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEI 134 >5MB9-A nrPDB Length = 590 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 13/96 (13%), Positives = 24/96 (25%), Gaps = 21/96 (21%) Query: 60 VRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREA 119 RT F + + + + VD +I ++ A Sbjct: 332 ARTVFEGFNR-------------LVESAVKKAGLDPLDVDEVIM----SGGTSNTPRIAA 374 Query: 120 ALGAGFSDKT----PAHTVTMACISANQAMTTGVGL 151 F + T P+ + S QA + Sbjct: 375 NFRYIFPESTRILAPSTDPSALNPSELQARGAALQA 410 >4KJD-A nrPDB Length = 488 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 29/143 (20%), Positives = 50/143 (34%), Gaps = 22/143 (15%) Query: 126 SDKTPAHTVTM-------ACISANQAMT--TGVGLIASGQCDVIVAGGVELM---SDVPI 173 T AHTV SA Q LI++ DVI+ GG + M Sbjct: 156 PAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDP 215 Query: 174 RHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPEL-PAVSEFSTSETMGHSADRLAA 232 + + + L+ + + L+ R+ + +L A + + + MG + Sbjct: 216 EYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLF-EPTEM 274 Query: 233 AFAVSRL--------EQDEYALR 247 + V+R E E A+R Sbjct: 275 KYDVNRNASADPSLAEMTEVAVR 297 >5LBT-A nrPDB Length = 237 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 22/58 (37%), Gaps = 4/58 (6%) Query: 52 RNVVVVDGVRTPFLLSGTSYKDLMPHDL---ARAALTGLLHRTSVPKEVVDYIIFGTV 106 + V++V + P S K++ +L L+ ++ D I GT+ Sbjct: 4 KKVLIVYAHQEP-KSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL 60 >4HA6-A nrPDB Length = 508 Score = 29.7 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 37/109 (33%), Gaps = 10/109 (9%) Query: 64 FLLSGTS--YKDLMPHDLARAALTGLLHRTSVPKEVV-DYIIFGTVIQEVKTSNVAREAA 120 G++ + D + LL R+ + V D G +I ++ Sbjct: 234 VGRQGSAEVFADQIVLCAGALESPALLMRSGIGPHDVLDAAGVGCLIDMPDIGRNLQDHL 293 Query: 121 LGAG----FSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGV 165 LGAG P + S + A A+GQ +++V GV Sbjct: 294 LGAGNLYAARKPVPPSRLQH---SESMAYMRADSFTAAGQPEIVVGCGV 339 >3U0E-A nrPDB Length = 428 Score = 29.3 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 27/150 (18%), Positives = 48/150 (32%), Gaps = 22/150 (14%) Query: 300 YGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYAT 359 G V A GA +++ E ALA G K + + S D D + A Sbjct: 246 DGFVIAG-------GAGVLVLEDLETALARGAKIYGEIVGYGATS-DGYDMVAPSGEGAI 297 Query: 360 PKVLEKAGLTM-NDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFN 418 ++ A T+ + ID H A + + + + + + Sbjct: 298 R-CMKMALSTVTSKIDYINPH----ATSTPAGDAPEIEAIRQIFGAGDVCPPIAATKSLT 352 Query: 419 NWGGSLSLGHPFGATGCRLVMAAANRLRKE 448 GH GATG + + + ++ Sbjct: 353 --------GHSLGATGVQEAIYSLLMMQNN 374 Score = 28.6 bits (62), Expect = 7.1, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 42/114 (36%), Gaps = 28/114 (24%) Query: 81 RAALTGLLHRTSVPKEVVDY----IIFGTVIQEVK----TSNVARE-------------- 118 A+ + + +E V II G+ + ++++ RE Sbjct: 97 HIAMDQAIADAGLTEEEVSNERTGIIMGSGGPSTRTIVDSADITREKGPKRVGPFAVPKA 156 Query: 119 ------AALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 A L F K ++++ AC ++N + +I G+ D + AGG E Sbjct: 157 MSSTASATLATFFKIKGINYSISSACATSNHCIGNAYEMIQYGKQDRMFAGGCE 210 >2IVO-A nrPDB Length = 330 Score = 29.0 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 10/27 (37%), Positives = 15/27 (55%), Gaps = 4/27 (14%) Query: 357 YATPKVLEKAGLTMNDIDAFEFHEAFS 383 K L +AG++++DID AFS Sbjct: 53 PLLRKALSEAGVSLDDIDVI----AFS 75 >5X41-A nrPDB Length = 280 Score = 27.8 bits (60), Expect = 9.5, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 23/61 (37%), Gaps = 3/61 (4%) Query: 311 LTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVL--EKAGL 368 L +GA+ ++ + +P + D +++D P T L + AG Sbjct: 219 LAEGAAEAVLSDRATLAKVALRPPLVI-DLALLARDHGLLAPEAPLPKTRDALAAQMAGW 277 Query: 369 T 369 T Sbjct: 278 T 278 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.127 0.349 Lambda K H 0.267 0.0395 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,466,603 Number of Sequences: 36641 Number of extensions: 672927 Number of successful extensions: 2549 Number of sequences better than 10.0: 112 Number of HSP's better than 10.0 without gapping: 136 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 1961 Number of HSP's gapped (non-prelim): 279 length of query: 474 length of database: 10,336,785 effective HSP length: 101 effective length of query: 373 effective length of database: 6,636,044 effective search space: 2475244412 effective search space used: 2475244412 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)